1. Historic American Buildings Survey James F. and Jean B. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. Historic American Buildings Survey James F. and Jean B. O'Gorman, Photographers October 1963 EXTERIOR FROM THE SOUTHEAST Gift of James F. and Jean B. O'Gorman - Stephen Higginson Jr. House, 7 Kirkland Street, Cambridge, Middlesex County, MA

2. Historic American Buildings Survey James F. and Jean B. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. Historic American Buildings Survey James F. and Jean B. O'Gorman, Photographers October 1963 EXTERIOR FROM THE SOUTHWEST Gift of James F. and Jean B. O'Gorman - Stephen Higginson Jr. House, 7 Kirkland Street, Cambridge, Middlesex County, MA

Jeans stability in collisional quantum dusty magnetoplasmas

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jamil, M.; Asif, M.; Mir, Zahid

2014-09-15

Jeans instability is examined in detail in uniform dusty magnetoplasmas taking care of collisional and non-zero finite thermal effects in addition to the quantum characteristics arising through the Bohm potential and the Fermi degenerate pressure using the quantum hydrodynamic model of plasmas. It is found that the presence of the dust-lower-hybrid wave, collisional effects of plasma species, thermal effects of electrons, and the quantum mechanical effects of electrons have significance over the Jeans instability. Here, we have pointed out a new class of dissipative instability in quantum plasma regime.

3. Historic American Buildings Survey James F. and Jean B. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

3. Historic American Buildings Survey James F. and Jean B. O'Gorman, Photographers October 1963 ORIGINAL MANTELPIECE AND WINDOW SHUTTERS, FIRST FLOOR Gift of James F. and Jean B. O'Gorman - Stephen Higginson Jr. House, 7 Kirkland Street, Cambridge, Middlesex County, MA

4. Historic American Buildings Survey James F. and Jean B. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

4. Historic American Buildings Survey James F. and Jean B. O'Gorman, Photographers October 1963 LATE 19th-CENTURY MANTELPIECE IN FIRST FLOOR ROOM Gift of James F. and Jean B. O'Gorman - Stephen Higginson Jr. House, 7 Kirkland Street, Cambridge, Middlesex County, MA

Jean Francheteau (1943-2010)

NASA Astrophysics Data System (ADS)

Sclater, John; Le Pichon, Xavier

2010-12-01

Jean Francheteau, pioneering marine geologist and geophysicist, AGU Fellow, and emeritus professor at the University of Brest (Université de Bretagne Occidentale), died on 21 July in St-Renan, Brittany, France, at the age of 67 after a long illness. With his passing, the field of Earth sciences lost a major contributor to the development of a definitive theory of plate tectonics and one of the first to make visual geological observations on the deep seafloor. Such scientific accomplishments, coupled with his personal charm and the ability to collaborate with researchers from many institutions, ensured that he had a huge influence not only on the world of research but also on teaching and the application of ethics to science. Jean arrived at Scripps Institution of Oceanography in La Jolla, Calif., in 1966 after obtaining a diploma in mining engineering at the prestigious Éole Nationale Supérieure de la Métallurgie et de l'Industrie des Mines in Nancy, France. He chose Victor Vacquier as his thesis supervisor and began working in Vic's lab with John Sclater, ostensibly on heat flow measurements.

The birth of the most important 18th century dental text: Pierre Fauchard's Le Chirurgien Dentiste.

PubMed

Spielman, Andrew I

2007-10-01

Pierre Fauchard (1678-1761) is considered the father of modern dentistry. His seminal book, Le Chirurgien Dentiste, ou Traité des Dents (1728), is the discipline's first complete work. During the five years preceding its publication (1723-1728), Pierre Fauchard sought the opinions, contributions, and "approbation" (approval) of 19 of his colleagues: six physicians, 12 surgeons, and one dentist. The first and most important contributor to the manuscript was Jean Devaux, surgeon and mentor to Fauchard. The next six reviewers were illustrious physicians and scientists of the time: Philippe Hecquet, Jean-Claude Adrien Helvetius, Jean Baptiste Silva, Antoine DeJussieu, Raymond Jacob Finot, and Antoine Benignus Winslow. The subsequent 12 reviewers were all sworn-surgeons (certified by St. Côme), including a lone dentist, Laudumiey, surgeon-dentist to His Majesty, Philip V, King of Spain. Fauchard knew that for dentistry to be regarded as a learned profession, and perhaps for Fauchard to be recognized as its leader, he needed the support and approval of the establishment before publishing his book. This is an account of how he attained this endorsement.

Demonic possession by Jean Lhermitte.

PubMed

Drouin, E; Péréon, T; Péréon, Y

2017-08-01

The name of the French neurologist and psychiatrist Jean Lhermitte (1877-1959) is most often associated with the sign he described back in 1927 in three patients with multiple sclerosis. We are reporting unpublished handwritten notes by Jean Lhermitte about 'demonic possession', which date from the 1950s. Drawing from his experiences in neuropsychiatry, Lhermitte gathered notable case reviews as well as individual case histories. For him, cases of demonic possession are of a psychiatric nature with social background exerting a strong influence. Like Freud did earlier, Lhermitte believes that the majority of those possessed people have been subjected to sexual trauma with scruples, often linked to religion. Demonic possession cases were not so rare in the 1950s but their number has nowadays declined substantially with the development of modern psychiatry. Copyright © 2017 L'Encéphale, Paris. Published by Elsevier Masson SAS. All rights reserved.

THERMALLY DRIVEN ATMOSPHERIC ESCAPE: TRANSITION FROM HYDRODYNAMIC TO JEANS ESCAPE

DOE Office of Scientific and Technical Information (OSTI.GOV)

Volkov, Alexey N.; Johnson, Robert E.; Tucker, Orenthal J.

2011-03-10

Thermally driven escape from planetary atmospheres changes in nature from an organized outflow (hydrodynamic escape) to escape on a molecule-by-molecule basis (Jeans escape) with increasing Jeans parameter, {lambda}, the ratio of the gravitational to thermal energy of the atmospheric molecules. This change is described here for the first time using the direct simulation Monte Carlo method. When heating is predominantly below the lower boundary of the simulation region, R{sub 0}, and well below the exobase of a single-component atmosphere, the nature of the escape process changes over a surprisingly narrow range of Jeans parameters, {lambda}{sub 0}, evaluated at R{sub 0}.more » For an atomic gas, the transition occurs over {lambda}{sub 0} {approx} 2-3, where the lower bound, {lambda}{sub 0} {approx} 2.1, corresponds to the upper limit for isentropic, supersonic outflow. For {lambda}{sub 0} > 3 escape occurs on a molecule-by-molecule basis and we show that, contrary to earlier suggestions, for {lambda}{sub 0} > {approx}6 the escape rate does not deviate significantly from the familiar Jeans rate. In a gas composed of diatomic molecules, the transition shifts to {lambda}{sub 0} {approx} 2.4-3.6 and at {lambda}{sub 0} > {approx}4 the escape rate increases a few tens of percent over that for the monatomic gas. Scaling by the Jeans parameter and the Knudsen number, these results can be applied to thermally induced escape of the major species from solar and extrasolar planets.« less

"Dancing Cannot Start Too Soon": Spiritual Education in the Thought of Jean Paul Friedrich Richter

ERIC Educational Resources Information Center

Pridmore, John

2004-01-01

Johann Paul Friedrich Richter (1763-1825) adopted the pen-name "Jean Paul" in honour of Jean Jaques Rousseau. His "Levana or the doctrine of education" ("Levana oder Erziehlehre") was once a standard text and required reading in teacher education. Outside Germany the name of Jean Paul is now little known and the…

Impact of porosity on Jeans instability in viscous quantum magnetoplasma

NASA Astrophysics Data System (ADS)

Prajapat, V.; Sutar, D. L.; Pensia, R. K.

2018-05-01

This paper treats the Jeans instability improved at the theoretical investigation of the presence of viscosity and resistivity in the porous medium. Following the normal mode analysis using the QMHD model, the dispersion relation is discussed for wave propagation in longitudinal and transverse direction. The Jeans criteria of instability are affected by the presence of porosity. The graphical presentation shows that porosity has a stabilizing effect while resistivity has destabilizing effect in the system.

Jeans instability with exchange effects in quantum dusty magnetoplasmas

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jamil, M., E-mail: jamil.gcu@gmail.com; Rasheed, A.; Rozina, Ch.

2015-08-15

Jeans instability is examined in magnetized quantum dusty plasmas using the quantum hydrodynamic model. The quantum effects are considered via exchange-correlation potential, recoil effect, and Fermi degenerate pressure, in addition to thermal effects of plasma species. It is found that the electron exchange and correlation potential have significant effects over the threshold value of wave vector and Jeans instability. The presence of electron exchange and correlation effect shortens the time of dust sound that comparatively stabilizes the self gravitational collapse. The results at quantum scale are helpful in understanding the collapse of the self-gravitating dusty plasma systems.

Jeans instability in collisional strongly coupled dusty plasma with radiative condensation and polarization force

DOE Office of Scientific and Technical Information (OSTI.GOV)

Prajapati, R. P., E-mail: prajapati-iter@yahoo.co.in; Bhakta, S.; Chhajlani, R. K.

2016-05-15

The influence of dust-neutral collisions, polarization force, and electron radiative condensation is analysed on the Jeans (gravitational) instability of partially ionized strongly coupled dusty plasma (SCDP) using linear perturbation (normal mode) analysis. The Boltzmann distributed ions, dynamics of inertialess electrons, charged dust and neutral particles are considered. Using the plane wave solutions, a general dispersion relation is derived which is modified due to the presence of dust-neutral collisions, strong coupling effect, polarization force, electron radiative condensation, and Jeans dust/neutral frequencies. In the long wavelength perturbations, the Jeans instability criterion depends upon strong coupling effect, polarization interaction parameter, and thermal loss,more » but it is independent of dust-neutral collision frequency. The stability of the considered configuration is analysed using the Routh–Hurwitz criterion. The growth rates of Jeans instability are illustrated, and stabilizing influence of viscoelasticity and dust-neutral collision frequency while destabilizing effect of electron radiative condensation, polarization force, and Jeans dust-neutral frequency ratio is observed. This work is applied to understand the gravitational collapse of SCDP with dust-neutral collisions.« less

The effect of spin induced magnetization on Jeans instability of viscous and resistive quantum plasma

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sharma, Prerana, E-mail: preranaiitd@rediffmail.com; Chhajlani, R. K.

2014-03-15

The effect of spin induced magnetization and electrical resistivity incorporating the viscosity of the medium is examined on the Jeans instability of quantum magnetoplasma. Formulation of the system is done by using the quantum magnetohydrodynamic model. The analysis of the problem is carried out by normal mode analysis theory. The general dispersion relation is derived from set of perturbed equations to analyse the growth rate and condition of self-gravitational Jeans instability. To discuss the influence of resistivity, magnetization, and viscosity parameters on Jeans instability, the general dispersion relation is reduced for both transverse and longitudinal mode of propagations. In themore » case of transverse propagation, the gravitating mode is found to be affected by the viscosity, magnetization, resistivity, and magnetic field strength whereas Jeans criterion of instability is modified by the magnetization and quantum parameter. In the longitudinal mode of propagation, the gravitating mode is found to be modified due to the viscosity and quantum correction in which the Jeans condition of instability is influenced only by quantum parameter. The other non-gravitating Alfven mode in this direction is affected by finite electrical resistivity, spin induced magnetization, and viscosity. The numerical study for the growth rate of Jeans instability is carried out for both in the transverse and longitudinal direction of propagation to the magnetic field. The effect of various parameters on the growth rate of Jeans instability in quantum plasma is analysed.« less

Jeans instability of rotating magnetized quantum plasma: Influence of radiation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Joshi, H., E-mail: hjoshi8525@yahoo.com; Pensia, R. K.

2015-07-31

The effect of radiative heat-loss function and rotation on the Jeans instability of quantum plasma is investigated. The basic set of equations for this problem is constructed by considering quantum magnetohydrodynamic (QMHD) model. Using normal mode analysis, the general dispersion relation is obtained. This dispersion relation is studied in both, longitudinal and transverse direction of propagations. In both case of longitudinal and transverse direction of propagation, the Jeans instability criterion is modified due to presence of radiative heat-loss function and quantum correction.

Quark Matter 2011 (QM11) Quark Matter 2011 (QM11)

NASA Astrophysics Data System (ADS)

2011-12-01

International Advisory Committee Antinori, FedericoPaic, Guy Braun-Munzinger, PeterPajares, Carlos Cifarelli, LuisaPeitzmann, Thomas Erazmus, BarbaraRedlich, Krzysztof Eskola, KariRiccati, Lodovico Gaardhøje, Jens JørgenRoland, Gunther Gale, CharlesRoy, Christelle Gelis, FrancoisSchukraft, Jürgen Giubellino, PaoloSinha, Bikash Greiner, CarstenSrivastava, Dinesh Gyulassy, MiklosStachel, Johanna Harris, JohnSteinberg, Peter Hatsuda, TetsuoStroth, Joachim Heinz, UlrichSugitate, Toru Jacak, BarbaraTserruya, Itzhak Karsch, FrithjofVelkovska, Julia Kharzeev, DimaWang, Enke Kodama, TakeshiWang, Xin, Nian Lévai, PéterWessels, Johannes Manko, VladislavXu, Nu Müller, BerndtZajc, William Ollitrault, Jean-Yves Organizing Committee Arleo, FrancoisDupieux, Pascal Bastid, NicoleFurget, Christophe Bourgeois, Marie-LaureGranier de Cassagnac, Raphael Bregant, MarcoGuernane, Rachid Carminati, FedericoHervet, Carnita Castillo, JavierKuhn, Christian Cheynis, BrigitteOlivier, Nathalie Conesa, DelValle, Zaida Connor, MichelleRenshall, Lucy Crochet, PhilippeSuire, Christophe Delagrange, HuguesTihinen, Ulla Program Committee Schutz, Yves (Chair)Baldisseri, Alberto Wiedemann, Urs (co-Chair)Safarik, Karel Aurenche, Patrick

Kinetic theory of Jeans instability of a dusty plasma.

PubMed

Pandey, B P; Lakhina, G S; Krishan, V

1999-12-01

A kinetic theory of the Jeans instability of a dusty plasma has been developed in the present work. The effect of grain charge fluctuations due to the attachment of electrons and ions to the grain surface has been considered in the framework of Krook's collisional model. We demonstrate that the grain charge fluctuations alter the growth rate of the gravitational collapse of the dusty plasma. The Jeans length has been derived under limiting cases, and its dependence on the attachment frequency is shown. In the absence of gravity, we see that the damping rate of the dust acoustic mode is proportional to the electron-dust collision frequency.

Jean Piaget's Debt to John Dewey

ERIC Educational Resources Information Center

Tanner, Daniel

2016-01-01

Jean Piaget became a veritable institution unto himself in education and psychology, largely as the result of his developmental-stage theory advanced over the second quarter of the twentieth century. Not until Piaget was 73 did he make mention of John Dewey's work at Dewey's laboratory school, founded in 1894 at the University of Chicago. But here…

Jeans, Sir James Hopwood (1877-1946)

NASA Astrophysics Data System (ADS)

Murdin, P.

2000-11-01

Astrophysicist, born in Ormskirk, Lancashire, England, worked at Cambridge, Princeton and Mount Wilson Observatory, and retired early to devote himself to research. Like CHANDRASEKHAR, Jeans worked on physical problems such as thermodynamics, applying the physics to astronomy, and writing lucid accounts of the whole field in books such as The Dynamical Theory of Gases (1904), Theoretical Mechanic...

The Method of Jean Louis Nicolet

ERIC Educational Resources Information Center

Gattegno, Caleb

2007-01-01

Jean Louis Nicolet is a Swiss teacher of mathematics who found his subject so fascinating that he was puzzled as to why so many pupils could not share this enjoyment in their studies. He came to a conclusion which is now supported by the results of psychological research into the learning process: he suggested that the mind does not spontaneously…

Jeans instability of magnetized quantum plasma: Effect of viscosity, rotation and finite Larmor radius corrections

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jain, Shweta, E-mail: jshweta09@gmail.com; Sharma, Prerana; Chhajlani, R. K.

2015-07-31

The Jeans instability of self-gravitating quantum plasma is examined considering the effects of viscosity, finite Larmor radius (FLR) corrections and rotation. The analysis is done by normal mode analysis theory with the help of relevant linearized perturbation equations of the problem. The general dispersion relation is obtained using the quantum magneto hydrodynamic model. The modified condition of Jeans instability is obtained and the numerical calculations have been performed to show the effects of various parameters on the growth rate of Jeans instability.

Jeans self gravitational instability of strongly coupled quantum plasma

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sharma, Prerana, E-mail: preranaiitd@rediffmail.com; Chhajlani, R. K.

2014-07-15

The Jeans self-gravitational instability is studied for quantum plasma composed of weakly coupled degenerate electron fluid and non-degenerate strongly coupled ion fluid. The formulation for such system is done on the basis of two fluid theory. The dynamics of weakly coupled degenerate electron fluid is governed by inertialess momentum equation. The quantum forces associated with the quantum diffraction effects and the quantum statistical effects act on the degenerate electron fluid. The strong correlation effects of ion are embedded in generalized viscoelastic momentum equation including the viscoelasticity and shear viscosities of ion fluid. The general dispersion relation is obtained using themore » normal mode analysis technique for the two regimes of propagation, i.e., hydrodynamic and kinetic regimes. The Jeans condition of self-gravitational instability is also obtained for both regimes, in the hydrodynamic regime it is observed to be affected by the ion plasma oscillations and quantum parameter while in the kinetic regime in addition to ion plasma oscillations and quantum parameter, it is also affected by the ion velocity which is modified by the viscosity generated compressional effects. The Jeans critical wave number and corresponding critical mass are also obtained for strongly coupled quantum plasma for both regimes.« less

The effect of suspended particles on Jean's criterion for gravitational instability

NASA Technical Reports Server (NTRS)

Wollkind, David J.; Yates, Kemble R.

1990-01-01

The effect that the proper inclusion of suspended particles has on Jeans' criterion for the self-gravitational instability of an unbounded nonrotating adiabatic gas cloud is examined by formulating the appropriate model system, introducing particular physically plausible equations of state and constitutive relations, performing a linear stability analysis of a uniformly expanding exact solution to these governing equations, and exploiting the fact that there exists a natural small material parameter for this problem given by N sub 1/n sub 1, the ratio of the initial number density for the particles to that for the gas. The main result of this investigation is the derivation of an altered criterion which can substantially reduce Jeans' original critical wavelength for instability. It is then shown that the existing discrepancy between Jeans' theoretical prediction using and actual observational data relevant to the Andromeda nebula M31 can be accounted for by this new criterion of assuming suspended particles of a reasonable grain size and distribution to be present.

Jean-Baptiste Labat and the buccaneer barbecue in seventeenth-century Martinique.

PubMed

Toczyski, Suzanne

2010-01-01

If, as the sociologist Pierre L. van den Berghe has suggested, cuisine is a significant expression of man's sociability, one might say that the seventeenth-century missionary Jean-Baptiste Labat was the single most social animal in the Caribbean islands in the 1690s. Although his primary responsibility on the island of Martinique was to serve the island's multiethnic population as a spiritual leader, le père Labat's memoirs chronicle the diverse culinary experiences of the missionary as he literally eats his way around the island, learning to prepare such delicacies as cocoa confit, roasted manatee, lizard en brochette, and parakeet en daube. Positing his unbridled interest in the culinary arts as a mark of his “obedience” to the duties assigned him as missionary, Labat's taxonomy of island delicacies and exotic tastes no doubt titillated the curiosity of his mainland readers while nevertheless grounding itself strongly in the values of order, authenticity, and industry so essential to Labat's apostolic mission. This article focuses on two “buccaneer barbecues” as examples of gastronomical experiences through which Labat was able to construct and negotiate new social, cultural, and symbolic meanings, exploring identity politics through the frame of the culinary arts in seventeenth-century Martinique.

[Fatal diseases and "imaginary" suffering. "Hypochondria" and "consumption" in the correspondence between Jean Paul and Johann Bernhard Hermann, with a perspective on Jean Paul's literature and aesthetics].

PubMed

Meier, Monika

2007-01-01

The German writerJean Paul (Johann Paul Friedrich Richter, 1763-1825) and his friendJohann Bernhard Hermann (1761-1790) became acquainted with the thoughts of late Enlightenment at the University of Leipzig. They particularly appreciated the anthropology of Ernst Platner, who taught philosophy and aesthetics as well as medicine. Their confidential correspondence contains reflections on their respective situation and well being. Both write about feeling ill and label their illness "hypochondria". In the course of the correspondence Jean Paul's understanding of hypochondria evolves from an illness of the entrails as he follows Hermann, who supports the modern concept of hypochondria as an illness of the nerves. Two important themes from this correspondence recur in Jean Paul's novels and tales: firstly, his way of expressing comfort is related to his aesthetics, and secondly, the satirical way of portraying at least certain aspects of illness as imaginary reappears in his first successful novel "The Invisible Lodge" (1793).

West Europe Report

DTIC Science & Technology

1987-05-27

Helios, Syracuse II Satellite Programs Detailed ( Jean -Paul Croize; LE FIGARO, 3 Feb 87) "* Increased Competition, New Markets for Weapons Sales...LIBERATION, 7-8 Mar 87) Problems, Advantages _ South East Asian Market, by Jean Guisnel °" Socialist Policy Shift, Editorial by Pierre Briancon...12466 CSO: 3554/118 73 MILITARY FRANCE HELIOS, SYRACUSE II SATELLITE PROGRAMS DETAILED Paris LE FIGARO in French 3 Feb 87 p 10 ^TLrticle by Jean

Jean-Antoine Nollet: The father of experimental electrospray.

PubMed

Dumont, Quentin; Cole, Richard B

2014-01-01

The development of electrospray ionization mass spectrometry (ESI-MS) was a 20th century occurrence that underwent rapid acceleration especially in the 1990's. However, long prior to its coupling with mass spectrometry, the electrification of liquids had been studied in a variety of contexts. Although initial reports describing cone formation upon electrification of water drops came out of England, the first true experiments investigating the electrospray phenomenon were performed in the middle of the 18th century by Abbé Jean-Antoine Nollet. The current report, associated with the French Regional Issue of Mass Spectrometry Reviews, examines the contributions of Abbé Nollet to the earliest understanding of the electrospray phenomenon. A description of his accomplishments is placed in the context of the societal and scientific developments of the "Age of Enlightenment" out of which Jean-Antoine Nollet arose. © 2013 Wiley Periodicals, Inc.

Jeans instability in a viscoelastic fluid

DOE Office of Scientific and Technical Information (OSTI.GOV)

Janaki, M. S.; Chakrabarti, N.; Banerjee, D.

2011-01-15

The well known Jeans instability is studied for a viscoelastic gravitational fluid using generalized hydrodynamic equations of motions. It is found that the threshold for the onset of instability appears at higher wavelengths in a viscoelastic medium. Elastic effects playing a role similar to thermal pressure are found to lower the growth rate of the gravitational instability. Such features may manifest themselves in matter constituting dense astrophysical objects.

Des premiers travaux de Le Verrier à la découverte de Neptune

NASA Astrophysics Data System (ADS)

Laskar, Jacques

2017-11-01

Urbain-Jean-Joseph Le Verrier was born in Saint-Lô on March 11, 1811. He entered the "École polytechnique" in 1831, from which he was to emerge eighth of his class two years later. After first devoting himself to chemistry, in 1836 he obtained a position as an astronomy assistant at the "École polytechnique". This choice will decide his future career, which culminates with the discovery of Neptune in 1846. Le Verrier wrote more than 200 contributions to the Comptes rendus de l'Académie des sciences. These contributions are very varied: some original articles, but also reports on publications published elsewhere, sometimes even simple notes of a single page. The whole set gives a very vivid vision of the development of the science of the 19th century. At that time, the Comptes rendus are really a reflection of the debates of the sessions of the Academy. They are published very quickly, and leave a large freedom of speech to the authors. They are therefore a snapshot of the sometimes lively polemics that animated the sessions of the French Academy of Sciences. In this limited essay, we will mainly look at the first years of the career of Le Verrier until the discovery of Neptune.

Design jeans for recycling: a supply chain case study in The Netherlands.

PubMed

van Bommel, Harrie; Goorhuis, Maarten

2014-11-01

Because the insight is raising that waste prevention needs an integral product chain approach, a product chain project was awarded with an International Solid Waste Association grant. The project decided to focus on jeans because of the large environmental impacts of cotton and the low recycling rates. The project used an open innovative approach by involving many actors from the different phases of the chain and included student and applied researchers. In a 'design jeans for recycling' students' workshop, prototypes of jeans that are easier to recycle have been developed. Integrating the new generation from different disciplines in the project proved to be very successful. The results show that an open innovation process can lead to very creative ideas and that lessons learned from this project could be used to develop new chain projects for other products. An important condition is that key actors are willing to cooperate in an open innovation approach. © The Author(s) 2014.

From past to current tectonics: Thematic issue dedicated to Jean-François Stéphan (1949-2013)

NASA Astrophysics Data System (ADS)

Manighetti, Isabelle

2016-01-01

This thematic issue of Comptes rendus Geoscience has been assembled to honor the memory of our late colleague and friend Jean-François Stéphan. Jean-François was a great scientist, specialized in tectonics, and a great colleague who devoted his time for his community. His work and actions deeply imprinted both the French and the International Earth Science communities. This volume brings together contributions of colleagues of Jean-François, who were also close friends or colleagues who knew and deeply appreciated him. Naturally, tectonics is the common theme of these contributions. Some of the papers presented here focus on tectonic questions and/or regions Jean-François worked on during his career; other papers present studies Jean-François motivated or encouraged in one way or another; other papers are simply tectonic studies he would have liked. Taken together, the nine papers of this thematic issue take the reader on a beautiful trip, from past to current tectonics.

J. Jeans' idealism about space and its influences on E.A. Milne at the dawn of modern cosmology

NASA Astrophysics Data System (ADS)

Macchia, Giovanni

2014-05-01

This paper deals with two important English scientists of the first half of the twentieth century: Edward Arthur Milne and James Hopwood Jeans. It examines the philosophical reasons that, in 1932, induced Milne to devote himself to the newborn modern cosmology. Among those reasons, it is argued that the most important ones were some of Jeans' philosophical statements regarding the new relativistic view of the expanding universe. In particular, Milne reacted to some confusing idealist opinions expressed by Jeans in the London newspaper The Times, in May 1932, in a debate on the expansion of the universe. Actually, as it will be shown, Jeans received many criticisms about the philosophical reasonings present in all of his popularizing works.

Staff - Jean A. Riordan | Alaska Division of Geological & Geophysical

Science.gov Websites

Penland Pkwy Anchorage, AK 99508 Phone: (907)754-3596 Fax: (907)696-0078 Email: jean.riordan@alaska.gov , Fairbanks, AK 99709 Phone: (907) 451-5000 Fax: (907) 451-5050 Contact DGGS Privacy Copyright State of Alaska

Conceptual Development: Piaget's Legacy. Jean Piaget Symposium Series.

ERIC Educational Resources Information Center

Scholnick, Ellin K., Ed.; Nelson, Katherine, Ed.; Gelman, Susan A., Ed.; Miller, Patricia H., Ed.

Based on the papers presented at the 1996 Symposium of the Jean Piaget Society and highlighting the extent to which Piaget's ideas have served to scaffold contemporary thinking about every aspect of conceptual development, this volume examines the nature of conceptual development, its foundations, and the sources of its novelties. The chapters…

Jean-Baptiste Belley-Mars: The Obscure Life, the Authentic Legacy.

ERIC Educational Resources Information Center

Fikes, Robert Jr.

1982-01-01

Describes how Jean-Baptiste Belley-Mars, a former slave, influenced Haitian history through his role in arguing for the abolition of slavery in the French colonies at the 1794 Paris National Convention. (MJL)

Physical interpretation of Jeans instability in quantum plasmas

DOE Office of Scientific and Technical Information (OSTI.GOV)

Akbari-Moghanjoughi, M.; International Centre for Advanced Studies in Physical Sciences and Institute for Theoretical Physics, Ruhr University Bochum, D-44780 Bochum

2014-08-15

In this paper, we use the quantum hydrodynamics and its hydrostatic limit to investigate the newly posed problem of Jeans instability in quantum plasmas from a different point of view in connection with the well-known Chandrasekhar mass-limit on highly collapsed degenerate stellar configurations. It is shown that the hydrodynamic stability of a spherically symmetric uniform quantum plasma with a given fixed mass is achieved by increase in its mass-density or decrease in the radius under the action of gravity. It is also remarked that for masses beyond the limiting Jeans-mass, the plasma becomes completely unstable and the gravitational collapse wouldmore » proceed forever. This limiting mass is found to depend strongly on the composition of the quantum plasma and the atomic-number of the constituent ions, where it is observed that heavier elements rather destabilize the quantum plasma hydrodynamically. It is also shown that the Chandrasekhar mass-limit for white dwarf stars can be directly obtained from the hydrostatic limit of our model.« less

West Europe Report.

DTIC Science & Technology

1984-08-10

Arbessier, Alexandre Astruc, Jean -Marie Benoist, Roberto Benzi, Gen de Boissieu, Claudie and Jacques Broyelle, Louis Cane, Jean -Paul Carrere, Jean ...Huyghe, Eugene Ionesco, Lucien Israel, Alain Laurent, Jacques Lautman, Emmanuel Le Roy Ladurie, Alain Malraux, Maria Mauban, Gen Guy Mery, Jean Negroni...several meetings between regional elected officials and Mr Jean - Jacques Servan-Schreiber. But one also dictated by experience. Fashionable "Boussois

A New Method to Directly Measure the Jeans Scale of the Intergalactic Medium Using Close Quasar Pairs

NASA Astrophysics Data System (ADS)

Rorai, Alberto; Hennawi, Joseph F.; White, Martin

2013-10-01

Although the baryons in the intergalactic medium (IGM) trace dark matter fluctuations on megaparsec scales, on smaller scales ~100 kpc, fluctuations are suppressed because the finite temperature gas is pressure supported against gravity, analogous to the classical Jeans argument. This Jeans filtering scale, which quantifies the small-scale structure of the IGM, has fundamental cosmological implications. First, it provides a thermal record of heat injected by ultraviolet photons during cosmic reionization events, and thus constrains the thermal and reionization history of the universe. Second, the Jeans scale determines the clumpiness of the IGM, a critical ingredient in models of cosmic reionization. Third, it sets the minimum mass scale for gravitational collapse from the IGM, and hence plays a pivotal role in galaxy formation. Unfortunately, it is extremely challenging to measure the Jeans scale via the standard technique of analyzing purely longitudinal Lyα forest spectra, because the thermal Doppler broadening of absorption lines along the line-of-sight, is highly degenerate with Jeans smoothing. In this work, we show that the Jeans filtering scale can be directly measured by characterizing the coherence of correlated Lyα forest absorption in close quasar pairs, with separations small enough ~100 kpc to resolve it. We present a novel technique for this purpose, based on the probability density function (PDF) of phase angle differences of homologous longitudinal Fourier modes in close quasar pair spectra. A Bayesian formalism is introduced based on the phase angle PDF, and Markov Chain Monte Carlo techniques are used to characterize the precision of a hypothetical Jeans scale measurement, and explore degeneracies with other thermal parameters governing the IGM. A semi-analytical model of the Lyα forest is used to generate a large grid (500) of thermal models from a dark matter only simulation. Our full parameter study indicates that a realistic sample of only

A NEW METHOD TO DIRECTLY MEASURE THE JEANS SCALE OF THE INTERGALACTIC MEDIUM USING CLOSE QUASAR PAIRS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rorai, Alberto; Hennawi, Joseph F.; White, Martin

2013-10-01

Although the baryons in the intergalactic medium (IGM) trace dark matter fluctuations on megaparsec scales, on smaller scales ∼100 kpc, fluctuations are suppressed because the finite temperature gas is pressure supported against gravity, analogous to the classical Jeans argument. This Jeans filtering scale, which quantifies the small-scale structure of the IGM, has fundamental cosmological implications. First, it provides a thermal record of heat injected by ultraviolet photons during cosmic reionization events, and thus constrains the thermal and reionization history of the universe. Second, the Jeans scale determines the clumpiness of the IGM, a critical ingredient in models of cosmic reionization.more » Third, it sets the minimum mass scale for gravitational collapse from the IGM, and hence plays a pivotal role in galaxy formation. Unfortunately, it is extremely challenging to measure the Jeans scale via the standard technique of analyzing purely longitudinal Lyα forest spectra, because the thermal Doppler broadening of absorption lines along the line-of-sight, is highly degenerate with Jeans smoothing. In this work, we show that the Jeans filtering scale can be directly measured by characterizing the coherence of correlated Lyα forest absorption in close quasar pairs, with separations small enough ∼100 kpc to resolve it. We present a novel technique for this purpose, based on the probability density function (PDF) of phase angle differences of homologous longitudinal Fourier modes in close quasar pair spectra. A Bayesian formalism is introduced based on the phase angle PDF, and Markov Chain Monte Carlo techniques are used to characterize the precision of a hypothetical Jeans scale measurement, and explore degeneracies with other thermal parameters governing the IGM. A semi-analytical model of the Lyα forest is used to generate a large grid (500) of thermal models from a dark matter only simulation. Our full parameter study indicates that a realistic

Cocteau on the Film; Conversations with Jean Cocteau.

ERIC Educational Resources Information Center

Fraigneau, Andre, Ed.

This book is the text of an interview with the French film-maker, Jean Cocteau. It is the corrected edition, with a new introduction by George Amberg, of the English translation of the early 1950 conversation in French. Cocteau discusses the aesthetics, creative aspects, and production processes of his own films and films in general. His approach…

Jean-Martin Charcot Pathologist, Neurologist, Psychiatrist and Physician

PubMed Central

Pandey, Sanjay

2012-01-01

Jean-Martin Charcot is known as father of modern neurology. Before him, neurology was only limited to select disorders like chorea. His contributions were not limited to neurology only, as he was instrumental in many new developments in the field of pathology, psychiatry, and internal medicine. Even after 100 years, Charcot`s clinical methods remain the pillar of modern neurology. PMID:23349597

Effect of polarization force on the Jeans instability in collisional dusty plasmas

NASA Astrophysics Data System (ADS)

A, ABBASI; M, R. RASHIDIAN VAZIRI

2018-03-01

The Jeans instability in collisional dusty plasmas has been analytically investigated by considering the polarization force effect. Instabilities due to dust-neutral and ion-neutral drags can occur in electrostatic waves of collisional dusty plasmas with self-gravitating particles. In this study, the effect of gravitational force on heavy dust particles is considered in tandem with both the polarization and electrostatic forces. The theoretical framework has been developed and the dispersion relation and instability growth rate have been derived, assuming the plane wave approximation. The derived instability growth rate shows that, in collisional dusty plasmas, the Jeans instability strongly depends on the magnitude of the polarization force.

Wise, Holistic Thinking: An Interview with Jean Sunde Peterson

ERIC Educational Resources Information Center

Henshon, Suzanna E.

2012-01-01

This article presents an interview with Jean Sunde Peterson, professor and director of school-counselor preparation in the Department of Educational Studies at Purdue University. She is a licensed mental health counselor and a national certified counselor, planning to return to clinical work with gifted children and adolescents and their families…

36 CFR 7.37 - Jean Lafitte National Historical Park.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 36 Parks, Forests, and Public Property 1 2011-07-01 2011-07-01 false Jean Lafitte National Historical Park. 7.37 Section 7.37 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF... to be taken; and (iii) Will not have an adverse effect on the ecosystem. (3) Violation of established...

36 CFR 7.37 - Jean Lafitte National Historical Park.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 36 Parks, Forests, and Public Property 1 2013-07-01 2013-07-01 false Jean Lafitte National Historical Park. 7.37 Section 7.37 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF... to be taken; and (iii) Will not have an adverse effect on the ecosystem. (3) Violation of established...

36 CFR 7.37 - Jean Lafitte National Historical Park.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 36 Parks, Forests, and Public Property 1 2012-07-01 2012-07-01 false Jean Lafitte National Historical Park. 7.37 Section 7.37 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF... to be taken; and (iii) Will not have an adverse effect on the ecosystem. (3) Violation of established...

36 CFR 7.37 - Jean Lafitte National Historical Park.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 36 Parks, Forests, and Public Property 1 2014-07-01 2014-07-01 false Jean Lafitte National Historical Park. 7.37 Section 7.37 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF... to be taken; and (iii) Will not have an adverse effect on the ecosystem. (3) Violation of established...

36 CFR 7.37 - Jean Lafitte National Historical Park.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 36 Parks, Forests, and Public Property 1 2010-07-01 2010-07-01 false Jean Lafitte National Historical Park. 7.37 Section 7.37 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF... to be taken; and (iii) Will not have an adverse effect on the ecosystem. (3) Violation of established...

Hannah Arendt & Jean Baudrillard: Pedagogy in the Consumer Society

ERIC Educational Resources Information Center

Norris, Trevor

2006-01-01

This paper considers the place of education within our "consumers' society", beginning with Hannah Arendt's account of the rise of consumerism to a position of political dominance and the resulting eclipse of public life. Connections are then made between Arendt's account of this rise and Jean Baudrillard's account of the postmodern proliferation…

Performing the Narrators in Jean Stafford's "The Hope Chest."

ERIC Educational Resources Information Center

JoAnn Niehaus, Sister

"The Hope Chest," a short story by Jean Stafford, offers a challenge to the oral interpreter of literature because it demands that the performer demonstrate its complex narrative levels. There are five distinct facets in the personality of the central character, Miss Bellamy: a lonely, fearful old lady; a shrewd, hospitable mistress of…

Official portrait of STS-65 backup Payload Specialist Jean-Jacques Favier

NASA Image and Video Library

1993-09-30

Official portrait of STS-65 International Microgravity Laboratory 2 (IML-2) backup Payload Specialist Jean-Jacques Favier. Favier is a member of the Centre National D'Etudes Spatiales (CNES), the French space agency.

Effect of rotation on Jeans instability of magnetized radiative quantum plasma

NASA Astrophysics Data System (ADS)

Joshi, H.; Pensia, R. K.

2017-03-01

The influence of rotation on the Jeans instability of homogeneous magnetized radiative quantum plasma is investigated. The basic equations of the problem are constructed and linearized by using the Quantum Magnetohydrodynamics (QMHD) model. The general dispersion relation is obtained by using the normal mode analysis technique, which is reduced for both the transverse and the longitudinal mode of propagations and further it is reduced for the axis of rotation parallel and perpendicular to the magnetic field. We found that the stabilizing effects of rotation are decreases for a strong magnetic field which is shown in the graphical representation. We also found that the quantum correction modified the condition of Jeans instability in both modes of propagation. The stabilizing effect of rotation is more increased in the presence of quantum correction.

Karl Popper and Jean Piaget: A Rationale for Constructivism

ERIC Educational Resources Information Center

Harlow, Steve; Cummings, Rhoda; Aberasturi, Suzanne M.

2006-01-01

The current faddish use of the term constructivism has taken on as many different definitions as the number of people attempting to define it. This essay clarifies the meaning of constructivism through an examination of Karl Popper's and Jean Piaget's theories. The authors provide a rationale for the use of Popper's paradigm of "Three Worlds" and…

In Touch with Kids: A Conversation with Jean Marzollo.

ERIC Educational Resources Information Center

Spodek, Bernard; Barrera, Rosalinda B.; Harris, Violet J.

2002-01-01

Interviews Jean Marzollo about her past, present, and future work in children's literature. Notes that her body of writing (more than 100 books of prose and poetry for young readers) transcends the boundaries of genre and disciplines, and is infused with a strong emphasis on rhyme and rhythm intended to capture the ears and minds of emergent and…

The effect of finite Larmor radius corrections on Jeans instability of quantum plasma

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sharma, Prerana; Chhajlani, R. K.

2013-09-15

The influence of finite Larmor radius (FLR) effects on the Jeans instability of infinitely conducting homogeneous quantum plasma is investigated. The quantum magnetohydrodynamic (QMHD) model is used to formulate the problem. The contribution of FLR is incorporated to the QMHD set of equations in the present analysis. The general dispersion relation is obtained analytically using the normal mode analysis technique which is modified due to the contribution of FLR corrections. From general dispersion relation, the condition of instability is obtained and it is found that Jeans condition is modified due to quantum effect. The general dispersion relation is reduced formore » both transverse and longitudinal mode of propagations. The condition of gravitational instability is modified due to the presence of both FLR and quantum corrections in the transverse mode of propagation. In longitudinal case, it is found to be unaffected by the FLR effects but modified due to the quantum corrections. The growth rate of Jeans instability is discussed numerically for various values of quantum and FLR corrections of the medium. It is found that the quantum parameter and FLR effects have stabilizing influence on the growth rate of instability of the system.« less

Tribute to Jean-Marie Mariotti

NASA Astrophysics Data System (ADS)

Lena, Pierre J.

2003-02-01

Jean-Marie Mariotti (1955 - 1998) prematurely passed away after too short a career of optician and astronomer. With his students, his contributions to the nascent field of high angular resolution at optical wavelengths, and especially to interferometry, both on the ground and in space, have been remarkable. Pioneering the use of single-mode optical fibers and integrated optics, he pushed the accuracy of visibility (amplitude) measurements to a fraction of a percent. His vision of a Mauna Kea kilometric interferometer using the existing giant telescopes is now becoming a reality with the 'OHANA project. His role in the emergence of the Very Large Telescope Interferometer (VLTI) and in the birth of the space mission DARWIN for exoplanets studies has been essential.

Home - Jean Mayer USDA Human Nutrition Research Center on Aging

Science.gov Websites

Jean Mayer USDA Human Nutrition Research Center on Aging Open Menu Close Menu Open Search Close Study #2965 Nutrition and Genetics Study ADAPT Study Bone material strength in normoglycemic and Resources My Plate for Older Adults Tufts Nutrition Magazine Calculating Calories and Nutrients in Meals

Ensaio de Pedagogia Comparada: Jean Jacques Rousseau (1712-1778) X Immanuel Kant (1724-1804) (Essay on Compared Pedagogy: Jean Jacques Rousseau (1712-1778) X Immanuel Kant (1724-1804).

ERIC Educational Resources Information Center

Fontanella, Francisco Cock

2000-01-01

Finds that, although the thought of Jean Jacques Rousseau is frequently cited as an influence on Immanuel Kant, this has no basis regarding pedagogical influence. Compares the "Projecto" and "Emilio" of Rousseau with Kant's "Pedagogia." (BT)

PREFACE: Nanosafe 2012: International Conferences on Safe Production and Use of Nanomaterials

NASA Astrophysics Data System (ADS)

Tardif, François

2013-04-01

, FR) Co-chair: Georgios KATALAGARIANAKIS (EC, BE) Mélanie AUFFAN (CEREGE, FR) Jorge BOCZKOWSKI (INSERM, FR) Jean-Yves BOTTERO (CEREGE, FR) Jacques BOUILLARD (INERIS, FR) Derk BROUWER (TNO, NL) Marie CARRIERE (CEA, FR) Claude EMOND (U. MONTREAL, CA) Cassandra ENGEMAN (UCSB, USA) Eric GAFFET (CNRS, FR) François GENSDARMES (IRSN, FR) Alexei GRINBAUM (CEA, FR) Antje GROBE (U.STUTTGART, DE) Peter HOET (KUL, BE) Eric QUEMENEUR (CEA, FR) Olivier LE BIHAN (INERIS, FR) Robert MUIR (NANEUM, UK) Tinh NGUYEN (NIST, USA) Bernd NOWACK (EMPA, CH) Günter OBERDÖRSTER (U. ROCHESTER, USA) David PUI (U. MINNESOTA, USA) Michael RIEDIKER (IST, CH) Yves SAMSON (CEA, FR) Ken TAKEDA (U. TOKYO, JP) Olivier WITSCHGER (INRS, FR) The PDF contains a list of sponsor logos, the conference programme and planning documents.

Can You Hear Me Now? Jean-Jacques Rousseau on Listening Education

ERIC Educational Resources Information Center

Laverty, Megan J.

2011-01-01

In this essay Megan J. Laverty argues that Jean-Jacques Rousseau's conception of humane communication and his proposal for teaching it have implications for our understanding of the role of listening in education. She develops this argument through a close reading of Rousseau's most substantial work on education, "Emile: Or, On Education". Laverty…

A Return to Love in William James and Jean-Luc Marion

ERIC Educational Resources Information Center

Rocha, Samuel

2009-01-01

In this essay Samuel Rocha primarily addresses, and challenges, the modern conception of reason and the lowly place of intuition, feeling, and love in what has become traditional philosophy and education. Drawing upon the rich thought of William James and Jean-Luc Marion, Rocha introduces the reader to a certain harmony between their ideas, most…

Jean-Louis Petit (1674-1750): a pioneer anatomist and surgeon and his contribution to orthopaedic surgery and trauma surgery.

PubMed

Markatos, Konstantinos; Androutsos, Georgios; Karamanou, Marianna; Tzagkarakis, Georgios; Kaseta, Maria; Mavrogenis, Andreas

2018-05-11

The purpose of this review is to summarize the life and work of Jean-Louis Petit, his inventions, his discoveries, and his impact on the evolution of surgery of his era. A thorough search of the literature was undertaken in PubMed and Google Scholar as well as in physical books in libraries to summarize current and classic literature on Petit. Jean-Louis Petit (1674-1750) was an eminent anatomist and surgeon of his era with an invaluable contribution to clinical knowledge, surgical technique, and instrumentation as well as innovative therapeutic modalities and basic scientific discoveries. Jean-Louis Petit was an innovative anatomist and surgeon as well as an excellent clinician of his era. He revolutionized the surgical technique of his era with a significant contribution to what would later become orthopaedic surgery.

Astronaut Jean-Francois Clervoy in white room on launch pad 39B

NASA Technical Reports Server (NTRS)

1994-01-01

In the white room at Launch Pad 39B, STS-66 mission specialist Jean-Francois Clervoy is assisted with his partial pressure launch/entry suit by close-out crew members Travis Thompson and Danny Wyatt (background) before entering the Space Shuttle Atlantis for its November 3 launch.

Documenting Reproduction and Inequality: Revisiting Jean Anyon's "Social Class and School Knowledge"

ERIC Educational Resources Information Center

Luke, Allan

2010-01-01

Jean Anyon's (1981) "Social Class and School Knowledge" was a landmark work in North American educational research. It provided a richly detailed qualitative description of differential, social class-based constructions of knowledge and epistemological stance. This essay situates Anyon's work in two parallel traditions of critical educational…

A Study of Displacement in Jean Rhys' Novel "Wide Sargasso Sea"

ERIC Educational Resources Information Center

Jamal, Inna Malissa bte Che; Singh, Hardev Kaur A/P Jujar; Mani, Manimangai

2014-01-01

"Wide Sargasso Sea," by Jean Rhys, is a novel filled with tragedy; two characters in conflict meet in circumstances not in their best interests but rather for other people. This novel is an illustration of the mad woman in the novel "Jane Eyre," by Charlotte Bronte, as the story of her life before madness is told in the novel…

The Right College: As Comfortable as Your Favorite Pair of Jeans

ERIC Educational Resources Information Center

Martin, Elizabeth Jean

2009-01-01

There is one thing on every shopping list that any student will be sure to choose accurately: the perfect pair of jeans. Indeed, this ubiquitous wardrobe staple is an important purchase requiring a variety of considerations, many of which correspond to another even more significant decision most students will make in the coming weeks, months or…

Astronaut Jean-Francois Clervoy in middeck during launch/entry training

NASA Technical Reports Server (NTRS)

1994-01-01

Astronaut Jean-Francois Clervoy, STS-66 international mission specialist, sits securely on a collapsible seat on the middeck of a shuttle trainer during a rehearsal of procedures to be followed during launch and entry phases of the scheduled November flight of STS-66. This rehearsal, held in the crew compartment trainer (CCT) of JSC's Shuttle mockup and integration laboratory, was followed by a training session on emergency egress procedures.

Developmental patterns of emission of scent compounds and related gene expression in roses of the cultivar Rosa x hybrida cv. 'Yves Piaget'.

PubMed

Chen, Xiaomin; Baldermann, Susanne; Cao, Shuyan; Lu, Yao; Liu, Caixia; Hirata, Hiroshi; Watanabe, Naoharu

2015-02-01

2-Phenylethanol (2PE) and 3,5-dimethoxytoluene (DMT) are characteristic scent compounds in specific roses such as Rosa x hybrida cv. 'Yves Piaget'. We analyzed the endogenous concentrations and emission of 2PE and DMT during the unfurling process in different floral organs, as well as changes in transcript levels of the two key genes, PAR and OOMT2. The emission of both 2PE and DMT increased during floral development to reach peaks at the fully unfurled stage. The relative transcripts of PAR and OOMT2 also increased during floral development. Whereas the maximum for OOMT2 was found at the fully unfurled stage (stage 4), similar expression levels of PAR were detected at stage 4 and the senescence stage (stage 6). The results demonstrate a positive correlation between the expression levels of PAR and OOMT2 and the emission of 2PE and DMT. In addition, endogenous volatiles and relative transcripts showed tissue- and development-specific patterns. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

The Autodidact in Defense of Himself: Jean-Jacques Rousseau and Knut Hamsun.

ERIC Educational Resources Information Center

Buttry, Dolores

1980-01-01

Describes Jean-Jacques Rousseau and Knut Hamsun as self-educated men who never ceased to warn of the evils of formal education. Quoting from their works, considers their feelings toward education as revealed in Rousseau's "Emile," with its description of ideal education, and in the ill effects of education on Hamsun's characters. (AYC)

Jean Piaget and Rudolf Steiner: Stages of Child Development and Implications for Pedagogy.

ERIC Educational Resources Information Center

Ginsburg, Iona H.

1982-01-01

The views of Jean Piaget and Rudolf Steiner concerning children's stages of development are compared and related to present-day instructional practices used in the Waldorf schools, which employ Steiner's ideas. Educational principles and practices used at the elementary school level are discussed. (PP)

Bidensmeyeri (Asteraceae, Coreopsideae): a new critically endangered species from Rapa, Austral Islands.

PubMed

Funk, Vicki A; Wood, Kenneth R

2014-01-01

Bidensmeyeri (Asteraceae/Compositae) is described and illustrated from Rapa, Austral Islands, (French Polynesia). This new species is presumed to be most closely related to Bidenssaint-johniana from nearby Marotiri Island. Bidensmeyeri may be distinguished from Bidenssaint-johniana based on the length of the peduncle (3 cm versus 10 cm), apex of the inner involucral bracts (glabrous vs. puberulent), smaller leaves (2.0-2.3 cm vs. 5-6 cm), and the general smaller size of the new species. Known from less than 50 individuals and restricted to one remote location, Bidensmeyeri falls into the IUCN Critically Endangered (CR) category. The new species is named in honor of Dr. Jean-Yves Meyer, Délégation à la Recherche, Polynésie Française.

West Europe Report, No. 2153

DTIC Science & Technology

1983-06-06

SEMAINE DE L’ENERGIE, 22 Mar 83) ...... ............. 10 Geothermal Energy Extracted From 5,000 Meters Below Surface ( Jean -Pierre Reillac; LES ECHOS...Unions Decry Lack of Anti-Unemployment Measures in New Plan ( Jean -Pierre Dumont; LE MONDE, 3-4 Apr 83) 34 GREECE Economic, Technical Cooperation...GEOTHERMAL ENERGY EXTRACTED FROM 5,000 METERS BELOW SURFACE Paris LES ECHOS in French 11 Apr 83 p 12 [Article by Jean -Pierre Reillac: "Limousin

[Mural paintings of Jean Coquet at the Desgenette Hospital in Lyon].

PubMed

Chauvin, Frédéric; Fischer, Louis-Paul

2010-01-01

René Nicolas Dufriche Desgenettes (1762-1837) became famous through two historical events: the first and most famous one is where he proved his courage by inoculating himself with the plague during the Syrian campaign in 1799; the second one, rarely represented in paintings, happened during the Russian retreat in 1812 when he was freed thanks to his reputation. Two wide fresco paintings facing each other in the hall of Desgenettes, a hospital built during World War Two, are witnesses of these two major events. Jean Coquet (1907-1990), a decorator, painter and glassblower, who worked at the Beaux-Arts School of Lyon, first as a decoration teacher than as its director, painted these two works of art. In 1946, he inserted them into an ornamental group constituted of ironworks, furniture, stained glass and ceramics. Two paintings from Antoine-Jean Gros (1771-1835) inspired these works: Bonaparte visiting the plague-stricken of Jaffa (1804) and Napoleon on the battlefield of Eylau (1808). With their academic composition and daring stylization those two frescoes represent in a modern and original way Desgenettes' life style, an archetype of what the military doctor is.

Astronaut Jean-Francois Clervoy in middeck during launch/entry training

NASA Technical Reports Server (NTRS)

1994-01-01

Wearing a training version of a partial pressure suit, Astronaut Jean-Francois Clervoy, STS-66 international mission specialist, secures himself on a collapsible seat on the middeck of a shuttle trainer during a rehearsal of procedures to be followed during launch and entry phases of the scheduled November flight of STS-66. This rehearsal, held in the crew compartment trainer (CCT) of JSC's Shuttle mockup and integration laboratory, was followed by a training session on emergency egress procedures.

Re-examining Distal Facies of the Grand Bay Ignimbrite at Fond St. Jean, Dominica

NASA Astrophysics Data System (ADS)

Ebner, N.; Frey, H. M.; Wirth, K. R.; Waters, L. E.; Manon, M. R. F.

2017-12-01

The Grand Bay ignimbrite in southern Dominica is a relatively young (43 ± 13 ka by U-Th of zircon), voluminous (0-.5-1 km3 on-land) and laterally extensive pyroclastic flow deposit spanning over 20 km2 that has been associated with the Micotrin volcanic center or Plat Pays complex. The Grand Bay ignimbrite typically occurs as a massive valley fill facies, approximately 9-14 meters thick, exposed on the southern coastal road, rich in white-light gray, relatively crystal rich (25-31%) andesitic (62-63.5 wt% SiO2, 16.7 wt% Al2O3, 6.5 wt % Fe2O3) pumice, whose mineral assemblage is dominated by plagioclase (22-25%), orthopyroxene (3-4%), and clinopyroxene (1-1.5%), in an unconsolidated gray ashy matrix. In the literature, distal facies of the Grand Bay ignimbrite have been proposed at Fond St. Jean (FSJ), but this supposition has recently been called into question. The 9 m thick stratified Fond St. Jean ignimbrite, (38,890 k.a. ± 600 B.P. by14C), is weathered yellow orange and overlies a 4 m thick lithified beach deposit on a sharp contact. Andesitic pumice clasts (60.5-64.5 wt% SiO2, 18 wt% Al2O3, 5.5 wt % Fe2O3) from the base of the FSJ ignimbrite contain similar mineral assemblages to Grand Bay clasts, however, FSJ pumices are relatively less crystal-rich (16-19%), contain significantly less plagioclase (13-16%), opx (1.0-1.5%), cpx (0.1 - 0.6%), and, most strikingly, up to 1% hornblende, which was not present in any Grand Bay samples. The lowermost three meters of the FSJ ignimbrite sequence is composed of meter thick sections of clast (5-7 cm pumice and ≤1 cm lithics) supported beds (70 cm), grading upwards into 30 cm of ash laminations and small pumice clasts (1-3 cm). Following a 40 cm bed of massive ash containing 1-3 cm clasts of pumice, the initial sequence repeats itself for 5 meters, with 30-40 cm lithic blocks in the uppermost unit. In addition to the stark stratigraphic and petrographic differences from the Grand Bay Beach exposure, Fe-Ti oxide

West Europe Report No. 2156

DTIC Science & Technology

1983-06-10

Then there is Jean - Jacques Servan-Schreiber who is said to favor this protectionist policy, behind the shelter of customs barriers. There are also...SANOMAT, 8 May 83 ) 89 FRANCE PCF’s Jerome on His Activities, 20th Soviet Congress, Solidarity ( Jean Jerome Interview; LE MATIN, 21 Apr 83...meeting place on bicycles, on foot and only in moderate numbers by car. Plaid shirts and jeans gave a somewhat [word missing] impres- sion of the youth

West Europe Report

DTIC Science & Technology

1987-01-21

BELGIUM Gol Criticizes CVP on Regional Financing Issues ( Jean Gol Interview; LE SOIR, 14 Nov 86) 52 FINLAND SPAIN Nordic Economic Unity Needs...FLNKS PLANS Paris ROUGE in French 27 Nov-3 Dec 86 p 15 [Interview with FLNKS President Jean -Marie Tjibaou by Alain Krivine in France; date not...given] [Text] Jean -Marie Tjibaou has just paid a visit to France. Chirac, noting his mistrust of the Kanaks, refused to see him. The president of the

Le pompage optique naturel dans le milieu astrophysique

NASA Astrophysics Data System (ADS)

Pecker, J.-C.

The title of this lecture abstracts only a part of it : the importance in astrophysics of the study of non-LTE situations has become considerable, as well in the stellar atmospheres as, still more, in the study of fortuitous coincidences as a mechanism of formation of emission line nebular spectra, or of molecular interstellar « masers ». Another part of this talk underlines the role of Kastler in his time, and describes his warm personality through his public reactions in front of the nuclear armement, of the Viet-Nam and Algerian wars, of the problems of political refugees... Kastler was a great scientist ; he was also a courageous humanist. 1976 : Les accords nucléaires du Brésil : allocution d'ouverture (19 mars). Colloque sur le sujet ci-dessus. 1976 : La promotion de la culture dans le nouvel ordre économique international, allocution à l'occasion d'une table ronde sur ce thème par l'UNESCO (23-27 juin 1976) ; « Sciences et Techniques », octobre 1976. 1979 : La bête immonde (avec J.-C. Pecker), « Le Matin », 20 mars. 1979 : Appel à nos ministres (avec J.-C. Pecker), « Le Monde », 13 décembre. 1979 : Le flou, le ténébreux, l'irrationnel (avec J.-C. Pecker), « Le Monde », 14 septembre. 1980 : Education à la paix, Préface, in : Publ. UNESCO. 1981 : Le vrai danger, « Le Monde », 6 août 1981. 1982 : Nucléaire civil et militaire, « Le Monde », 1er juin 1982. 1982 : Les scientifiques face à la perspective d'holocauste nucléaire (texte inédit). Le titre de cette communication en résume seulement une partie : l'importance prise en astrophysique par l'analyse des situations hors ETL est devenue considérable, qu'il s'agisse des atmosphères stellaires, ou plus encore, des coïncidences fortuites de la formation des spectres d'émission nébulaires, ou des « masers » moléculaires interstellaires. Une autre partie de cet exposé souligne le rôle de Kastler dans son époque, et décrit sa personnalité généreuse à travers ses r

Modified jeans instability for dust grains in a plasma.

PubMed

Delzanno, G L; Lapenta, G

2005-05-06

An investigation of the properties of linear stability is conducted for a system consisting of particles having mass m and charge q, interacting through the gravitational and electrostatic force (Jeans instability). However, in light of recent works showing that dust particles in a plasma can have a Lennard-Jones-like shielding potential, a new set of equations has been derived, where the electrostatic interaction among the dust particles is Lennard-Jones-like instead of Coulomb-like. A new condition for the gravitational instability is derived, showing a broader spectrum of unstable modes with faster growth rates.

The early evolution of Jean Piaget's clinical method.

PubMed

Mayer, Susan Jean

2005-11-01

This article analyzes the early evolution of Jean Piaget's renowned "clinical method" in order to investigate the method's strikingly original and generative character. Throughout his 1st decade in the field, Piaget frequently discussed and justified the many different approaches to data collection he used. Analysis of his methodological progression during this period reveals that Piaget's determination to access the genuine convictions of children eventually led him to combine 3 distinct traditions in which he had been trained-naturalistic observation, psychometrics, and the psychiatric clinical examination. It was in this amalgam, first evident in his 4th text, that Piaget discovered the clinical dynamic that would drive the classic experiments for which he is most well known.

Jean-Martin Charcot's Role in the 19th Century Study of Music Aphasia

ERIC Educational Resources Information Center

Johnson, Julene K.; Lorch, Marjorie; Nicolas, Serge; Graziano, Amy

2013-01-01

Jean-Martin Charcot (1825-93) was a well-known French neurologist. Although he is widely recognized for his discovery of several neurological disorders and his research into aphasia, Charcot's ideas about how the brain processes music are less well known. Charcot discussed the music abilities of several patients in the context of his "Friday…

Jean Vigo's "Zéro De Conduite" and the Spaces of Revolt

ERIC Educational Resources Information Center

Vanobbergen, Bruno; Grosvenor, Ian; Simon, Frank

2014-01-01

In this article we will contribute to the contemporary theoretical debate about film by considering, from a history-of-education perspective, the film "Zéro de conduite" by Jean Vigo (1905--1934). This film is classified under the umbrella of "poetic realism": a product of "cinéma de gauche" and an avant-gardist,…

Jeans Instability of the Self-Gravitating Viscoelastic Ferromagnetic Cylinder with Axial Nonuniform Rotation and Magnetic Field

NASA Astrophysics Data System (ADS)

Dhiman, Joginder Singh; Sharma, Rajni

2017-12-01

The effects of nonuniform rotation and magnetic field on the instability of a self gravitating infinitely extending axisymmetric cylinder of viscoelastic ferromagnetic medium have been studied using the Generalised Hydrodynamic (GH) model. The non-uniform magnetic field and rotation are acting along the axial direction of the cylinder and the propagation of the wave is considered along the radial direction, while the ferrofluid magnetization is taken collinear with the magnetic field. A general dispersion relation representing magnetization, magnetic permeability and viscoelastic relaxation time parameters is obtained using the normal mode analysis method in the linearized perturbation equation system. Jeans criteria which represent the onset of instability of self gravitating medium are obtained under the limits; when the medium behaves like a viscous liquid (strongly coupled limit) and a Newtonian liquid (weakly coupled limit). The effects of various parameters on the Jeans instability criteria and on the growth rate of self gravitating viscoelastic ferromagnetic medium have been discussed. It is found that the magnetic polarizability due to ferromagnetization of medium marginalizes the effect of non-uniform magnetic field on the Jeans instability, whereas the viscoelasticity of the medium has the usual stabilizing effect on the instability of the system. Further, it is found that the cylindrical geometry is more stable than the Cartesian one. The variation of growth rate against the wave number and radial distance has been depicted graphically.

Gravity or turbulence? - III. Evidence of pure thermal Jeans fragmentation at ˜0.1 pc scale

NASA Astrophysics Data System (ADS)

Palau, Aina; Ballesteros-Paredes, Javier; Vázquez-Semadeni, Enrique; Sánchez-Monge, Álvaro; Estalella, Robert; Fall, S. Michael; Zapata, Luis A.; Camacho, Vianey; Gómez, Laura; Naranjo-Romero, Raúl; Busquet, Gemma; Fontani, Francesco

2015-11-01

We combine previously published interferometric and single-dish data of relatively nearby massive dense cores that are actively forming stars to test whether their `fragmentation level' is controlled by turbulent or thermal support. We find no clear correlation between the fragmentation level and velocity dispersion, nor between the observed number of fragments and the number of fragments expected when the gravitationally unstable mass is calculated including various prescriptions for `turbulent support'. On the other hand, the best correlation is found for the case of pure thermal Jeans fragmentation, for which we infer a core formation efficiency around 13 per cent, consistent with previous works. We conclude that the dominant factor determining the fragmentation level of star-forming massive dense cores at 0.1 pc scale seems to be thermal Jeans fragmentation.

An Interview with Mark Ahlness and Jean Carmody about the Earth Day Groceries Project.

ERIC Educational Resources Information Center

Strangman, Nicole

2002-01-01

Outlines an interview with Mark Ahlness, a third-grade teacher at Arbor Heights Elementary School in Seattle, Washington, and Jean Carmody, an art teacher at two elementary schools in Cranston, Rhode Island. Describes their collaborative project called the Earth Day Groceries Project. Explains that in this Internet project, students decorate…

Jean Piaget: Images of a life and his factory.

PubMed

Burman, Jeremy Trevelyan

2012-08-01

In this article, I use a new book about Jean Piaget to introduce a new historical method: examining "psychological factories." I also discuss some of the ways that "Great Men" are presented in the literature, as well as opportunities for new projects if one approaches the history of the discipline differently and examines the conditions that made that greatness possible. To that end, the article includes many details about Piaget that have never before been discussed in English. Attention is drawn, in particular, to Piaget's collaborators: the hundreds of workers at his factory in Geneva, many of whom were women. (PsycINFO Database Record (c) 2012 APA, all rights reserved).

Un cosmologiste oublié: Jean Henri Lambert

NASA Astrophysics Data System (ADS)

Débarbat, Suzanne; Lévy, Jacques

Si les travaux de Kepler ont eu une large influence sure les progrès réalisés en astronomie au cours du 17e siècle, le Siècle de lumières a vu apparaître de nouvelles conceptions. La court vie de J.H. lambert s'inscrit dans le 18e siècle. Il s'agit d'un nom bien connu dans différents domaines (photométrie, projections cartographiques, mathématiques appliquées, etc.); mais il n'est guàre mentionné en cosmologie, alors que Lambert y a fourni une contribution originale offrant quelques suprenantes anticipations...

The Enunciation of the Subject: Sharing Jean-Luc Nancy's Singular Plural in the Classroom

ERIC Educational Resources Information Center

Collins, Ashok

2015-01-01

This article seeks to explore the implications of Jean-Luc Nancy's reading of the subject for educational philosophy by connecting his re-interpretation of Descartes to his later thinking on what he names the ontological singular plural. Nancy's re-imagining of the Cogito coalesces around the figure of the mouth ("la bouche") through…

[Jean-Martin Charcot in German neurology].

PubMed

Lehmann, H C; Hartung, H-P; Kieseier, B C

2004-02-01

Jean-Martin Charcot (1825-1893), well known as the founder of modern neurology, was the most celebrated neurologist in the nineteenth century. His international success stemmed not only from mastery descriptions of various neurological disorders but also from his many contacts with scientists all over the world. The aim of this article is to review Charcot's ambivalent relationship to German neuropsychiatry of the time and to examine the German reception of his personality and work. Wilhelm Erb, Ludwig Hirt, Ernst von Leyden, Max Nonne, Adolph Strümpell, and other German physicians cultivated -to varying degrees - professional contacts with Charcot and, based on the fascination of his personality and significance of his work, were long and intensively influenced by the Salpêtrière school. The extent of their admiration became apparent in 1882 by the award of an honorary doctorate to Charcot by the University of Würzburg. Along with increasingly severe criticism of Charcot's research on hysteria and hypnosis, most German neuropsychiatrists became estranged, without neglecting his importance to the development of neurology in Germany.

LeEix1 functions as a decoy receptor to attenuate LeEix2 signaling.

PubMed

Bar, Maya; Sharfman, Miya; Avni, Adi

2011-03-01

The receptors for the fungal elicitor EIX (LeEix1 and LeEix2) belong to a class of leucine-rich repeat cell-surface glycoproteins with a signal for receptor-mediated endocytosis. Both receptors are able to bind the EIX elicitor while only the LeEix2 receptor mediates defense responses. We show that LeEix1 acts as a decoy receptor and attenuates EIX induced internalization and signaling of the LeEix2 receptor. We demonstrate that BAK1 binds LeEix1 but not LeEix2. In plants where BAK1 was silenced, LeEix1 was no longer able to attenuate plant responses to EIX, indicating that BAK1 is required for this attenuation. We suggest that LeEix1 functions as a decoy receptor for LeEix2, a function which requires the kinase activity of BAK1.

Profiles of international archives: Les archives Jean Piaget, University of Geneva, Switzerland.

PubMed

Burman, Jeremy Trevelyan

2013-05-01

This research report provides a look behind closed doors at the Jean Piaget Archives in Geneva, Switzerland. It situates the potential visitor, contextualizes the Archives in its own history, and then describes what scholars can expect to find. New details about Piaget's views on Equal Rights and Equal Pay are also provided, including a look at how they affected the women who worked his factory (esp. Bärbel Inhelder). (PsycINFO Database Record (c) 2013 APA, all rights reserved).

Jean Rotz and the Marine Chart, 1542

NASA Astrophysics Data System (ADS)

Taylor, E. G. R.

This paper was first published in the Journal in 1954 (Vol. 7, p. 138). It is followed by comments from Michael Richey.At the time (1542) when Jean Rotz presented Henry VIII with a variation compass, and an accompanying treatise on its making and use, the question of magnetic variation was an acute one. It formed part of a wider controversy concerning the general validity of the sea-chart which had been raised among seamen. As to this, Dr Pedro Nunez, writing a treatise in 1537 addressed to his friend and pupil the Infante Dom Luys of Portugal, said that there were skilled pilots who derided the chart and declared it to be - the falsest thing in the world. Hastening to its defence, Nunez dealt at length with the navigating errors introduced by ignoring the convergence of the meridians, and showed besides that a rhumb, or line of constant bearing was a spiral curve on the globe.

Jeans that fit: weighing the mass of the Milky Way analogues in the ΛCDM universe

NASA Astrophysics Data System (ADS)

Kafle, Prajwal R.; Sharma, Sanjib; Robotham, Aaron S. G.; Elahi, Pascal J.; Driver, Simon P.

2018-04-01

The spherical Jeans equation is a widely used tool for dynamical study of gravitating systems in astronomy. Here, we test its efficacy in robustly weighing the mass of Milky Way analogues, given they need not be in equilibrium or even spherical. Utilizing Milky Way stellar haloes simulated in accordance with Λ cold dark matter (ΛCDM) cosmology by Bullock and Johnston and analysing them under the Jeans formalism, we recover the underlying mass distribution of the parent galaxy, within distance r/kpc ∈ [10, 100], with a bias of ˜ 12 per cent and a dispersion of ˜ 14 per cent. Additionally, the mass profiles of triaxial dark matter haloes taken from the SURFS simulation, within scaled radius 0.2 < r/rmax < 3, are measured with a bias of ˜ - 2.4 per cent and a dispersion of ˜ 10 per cent. The obtained dispersion is not because of Poisson noise due to small particle numbers as it is twice the later. We interpret the dispersion to be due to the inherent nature of the ΛCDM haloes, for example being aspherical and out-of-equilibrium. Hence, the dispersion obtained for stellar haloes sets a limit of about 12 per cent (after adjusting for random uncertainty) on the accuracy with which the mass profiles of the Milky Way-like galaxies can be reconstructed using the spherical Jeans equation. This limit is independent of the quantity and quality of the observational data. The reason for a non-zero bias is not clear, hence its interpretation is not obvious at this stage.

The copy of the Essays of Jean Rey, used by Bayen and Gobet, at the BIU Sante, pole Pharmacie.

PubMed

Lafont, Olivier

2016-06-01

The copy of the innovative book written by Jean Rey in 1630, entitied : The Essays on the reasons why the weight of stain and lead increased when they were burnt, which is nowadays kept in the BIU Sante, pole Pharmacie, proved to be the authentic copy which had been used by Pierre Bayer when he rediscovered Jean Rey's Works. It was also the same copy that Gobey used when he real- ized his new edition of the Essays in 1777. This copy first belonged to M. de Villars from La Rochelle, and then was acquired by M. de Villiers, who accepted to lend it to Bayen. The probes for this identification were detailed in the article.

When the Jeans Do Not Fit: How Stellar Feedback Drives Stellar Kinematics and Complicates Dynamical Modeling in Low-mass Galaxies

DOE Office of Scientific and Technical Information (OSTI.GOV)

El-Badry, Kareem; Quataert, Eliot; Wetzel, Andrew R.

In low-mass galaxies, stellar feedback can drive gas outflows that generate non-equilibrium fluctuations in the gravitational potential. Using cosmological zoom-in baryonic simulations from the Feedback in Realistic Environments project, we investigate how these fluctuations affect stellar kinematics and the reliability of Jeans dynamical modeling in low-mass galaxies. We find that stellar velocity dispersion and anisotropy profiles fluctuate significantly over the course of galaxies’ starburst cycles. We therefore predict an observable correlation between star formation rate and stellar kinematics: dwarf galaxies with higher recent star formation rates should have systemically higher stellar velocity dispersions. This prediction provides an observational test ofmore » the role of stellar feedback in regulating both stellar and dark-matter densities in dwarf galaxies. We find that Jeans modeling, which treats galaxies as virialized systems in dynamical equilibrium, overestimates a galaxy’s dynamical mass during periods of post-starburst gas outflow and underestimates it during periods of net inflow. Short-timescale potential fluctuations lead to typical errors of ∼20% in dynamical mass estimates, even if full three-dimensional stellar kinematics—including the orbital anisotropy—are known exactly. When orbital anisotropy is not known a priori, typical mass errors arising from non-equilibrium fluctuations in the potential are larger than those arising from the mass-anisotropy degeneracy. However, Jeans modeling alone cannot reliably constrain the orbital anisotropy, and problematically, it often favors anisotropy models that do not reflect the true profile. If galaxies completely lose their gas and cease forming stars, fluctuations in the potential subside, and Jeans modeling becomes much more reliable.« less

STS-84 Mission Specialist Jean-Francois Clervoy in white room

NASA Technical Reports Server (NTRS)

1997-01-01

KENNEDY SPACE CENTER, FLA. -- STS-84 Mission Specialist Jean- Francois Clervoy prepares to enter the Space Shuttle Atlantis at Launch Pad 39A with help from white room closeout crew members. The fourth Shuttle mission of 1997 will be the sixth docking of the Space Shuttle with the Russian Space Station Mir. The commander is Charles J. Precourt. The pilot is Eileen Marie Collins. The five mission specialists are C. Michael Foale, Carlos I. Noriega, Edward Tsang Lu, Jean-Francois Clervoy of the European Space Agency and Elena V. Kondakova of the Russian Space Agency. The planned nine-day mission will include the exchange of Foale for U.S. astronaut and Mir 23 crew member Jerry M. Linenger, who has been on Mir since Jan. 15. Linenger transferred to Mir during the last docking mission, STS-81; he will return to Earth on Atlantis. Foale is slated to remain on Mir for about four months until he is replaced in September by STS-86 Mission Specialist Wendy B. Lawrence. During the five days Atlantis is scheduled to be docked with the Mir, the STS-84 crew and the Mir 23 crew, including two Russian cosmonauts, Commander Vasily Tsibliev and Flight Engineer Alexander Lazutkin, will participate in joint experiments. The STS-84 mission also will involve the transfer of more than 7,300 pounds of water, logistics and science equipment to and from the Mir. Atlantis is carrying a nearly 300-pound oxygen generator to replace one of two Mir units which have experienced malfunctions. The oxygen it generates is used for breathing by the Mir crew.

Evolution of the phase-space density and the Jeans scale for dark matter derived from the Vlasov-Einstein equation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Piattella, O.F.; Rodrigues, D.C.; Fabris, J.C.

2013-11-01

We discuss solutions of Vlasov-Einstein equation for collisionless dark matter particles in the context of a flat Friedmann universe. We show that, after decoupling from the primordial plasma, the dark matter phase-space density indicator Q = ρ/(σ{sub 1D}{sup 2}){sup 3/2} remains constant during the expansion of the universe, prior to structure formation. This well known result is valid for non-relativistic particles and is not ''observer dependent'' as in solutions derived from the Vlasov-Poisson system. In the linear regime, the inclusion of velocity dispersion effects permits to define a physical Jeans length for collisionless matter as function of the primordial phase-spacemore » density indicator: λ{sub J} = (5π/G){sup 1/2}Q{sup −1/3}ρ{sub dm}{sup −1/6}. The comoving Jeans wavenumber at matter-radiation equality is smaller by a factor of 2-3 than the comoving wavenumber due to free-streaming, contributing to the cut-off of the density fluctuation power spectrum at the lowest scales. We discuss the physical differences between these two scales. For dark matter particles of mass equal to 200 GeV, the derived Jeans mass is 4.3 × 10{sup −6}M{sub ⊙}.« less

Astronaut Jean-Francois Clervoy in middeck during launch/entry training

NASA Image and Video Library

1994-06-23

S94-40074 (23 June 1994) --- Astronaut Jean-Francois Clervoy, STS-66 international mission specialist, sits securely on a collapsible seat on the middeck of a Shuttle trainer during a rehearsal of procedures to be followed during launch and entry phases of his scheduled November flight. This rehearsal, held in the crew compartment trainer of the Johnson Space Center's (JSC) Shuttle Mockup and Integration Laboratory, was followed by a training session on emergency egress procedures. Clervoy, a European astronaut, will join five NASA astronauts for a week and a half aboard the Space Shuttle Atlantis in Earth-orbit in support of the Atmospheric Laboratory for Applications and Science (ATLAS-3).

Le ciment brûle toujours

PubMed Central

Lebreton, T.; Fontaine, M.; Le Floch, R.

2017-01-01

Summary Les brûlures chimiques par ciment représentent une cause fréquente de corrosion cutanée en France. Elles nécessitent fréquemment un traitement chirurgical. Notre étude rétrospective concerne tous les patients admis pour une brûlure par ciment dans le service entre 2004 et 2016. Quarante-neuf patients âgés de 21 à 71 ans ont été pris en charge dans le centre des brûlés du Centre Hospitalier Saint Joseph Saint Luc à Lyon entre 2004 et 2016. La population concernée était majoritairement masculine, relativement jeune (44 ans en moyenne) et professionnellement active. Les brûlures survenaient principalement dans le cadre d’accidents domestiques (78%). Elles étaient profondes et atteignaient majoritairement les membres inférieurs, de façon bilatérale. La surface brûlée représentait 3% de la surface cutanée totale. Presque tous les patients (98%) ont nécessité une prise en charge chirurgicale pour excision et autogreffe de peau mince. Un seul patient a bénéficié d’une cicatrisation dirigée. Le délai moyen entre la brûlure et la chirurgie était de 13 jours et la durée moyenne d’hospitalisation de 8 jours. Sept patients ont nécessité une prise en charge en centre de rééducation à leur sortie du service. Cette étude confirme la sévérité des brûlures chimiques par ciment. Elle met également en avant l’impact que peut avoir ce type de brûlure en terme de retentissement socio-économique dans une population de patients majoritairement jeune et active. Elle insiste sur le fait que des mesures doivent être prises afin d’informer cette population rarement professionnelle sur les risques encourus lors du mésusage du ciment. La réglementation actuelle, classant le ciment comme irritant, ne prend pas en compte son caractère corrosif et devrait être amendée. PMID:28592929

A model for the construction of elementary concepts

NASA Astrophysics Data System (ADS)

von Glasersfeld, Ernst

1999-03-01

In his paper Les épistémologies constructivistes: Un nouveau commencement (Sciences de la Société, n°40, 1997), Jean-Louis Le Moigne poses the question: "Le rêve d'une connaissance autoréférentielle se fondant sur elle-même, est sans doute fascinant … Mais est-il scientifiquement raisonnable?". Building on the work of Jean Piaget, I shall try to show through a developmental analysis of elementary, scientifically relevant concepts, such as `change', `object permanence', `space', and `time', that the notion of the thinking subject's construction of knowledge constitutes a more reasonable foundation for science than the traditional belief in the representation of objective reality.

Jean C. Zenklusen, M.S., Ph.D., Discusses the NCI Genomics Data Commons at AACR 2014 - TCGA

Cancer.gov

At the AACR 2014 meeting, Dr. Jean C. Zenklusen, Director of The Cancer Genome Atlas Program Office, highlights the Genomics Data Commons, a harmonized data repository that will allow simultaneous access and analysis of NCI genomics data, including The Ca

Illness as the saturated phenomenon: the contribution of Jean-Luc Marion.

PubMed

Grīnfelde, Māra

2018-05-24

During the last few decades, many thinkers have advocated for the importance of the phenomenological approach in developing the understanding of the lived experience of illness. In their attempts, they have referred to ideas found in the history of phenomenology, most notably, in the works of Edmund Husserl, Martin Heidegger, Maurice Merleau-Ponty and Jean-Paul Sartre. The aim of this paper is to sketch out an interpretation of illness based on a yet unexplored conceptual framework of the phenomenology of French thinker Jean-Luc Marion. Focusing on concepts of the saturated phenomenon and flesh, the paper develops an interpretation of illness as the saturated phenomenon, which highlights a variety of dimensions of illness already elaborated within the phenomenology of medicine, such as the affective dimension of illness, the disruptive dimension of illness, the transformed perception of the self in illness, mineness of flesh in illness and the inexpressible and hermeneutical dimension of illness. In addition to that, the paper explores some of the consequences the proposed interpretation of illness offers regarding the nature of illness and health. It is argued that illness in its essence is very similar to the experience of other saturated phenomena, suggesting that the difference between them does not lie within the character of the affective givenness, but rather within the dynamic relationship between the affective givenness and its conceptualization. It is also shown that the experience of health is compatible with the experience of saturation and thus is not limited to the tacit and harmonious background state.

A Comparison of Workers Employed in Hazardous Jobs in Terms of Job Satisfaction, Perceived Job Risk and Stress: Turkish Jean Sandblasting Workers, Dock Workers, Factory Workers and Miners

ERIC Educational Resources Information Center

Sunal, Ayda Buyuksahin; Sunal, Onur; Yasin, Fatma

2011-01-01

The purpose of this study is to compare job satisfaction, perception of job risk, stress symptoms and vulnerability to stress of miners, dock workers, jean sandblasting workers and factory workers. A job satisfaction scale and stress audit scale were applied to 220 workers. Results revealed that dock and jean sandblasting workers perceived their…

[Armand-Jean de Mauvillain (1620-1685), Molière's friend and counsellor, Dean of the Faculté de médecine de Paris (1666-1668)].

PubMed

Warolin, Christian

2005-01-01

Armand-Jean de Mauvillain was Marguerite Cardinal's and Jean de Mauvillain's son. Jean de Mauvillain was successively the King's and Gaston d'Orléans surgeon. His ancestors were native of the Poitou region. The Mauvillains' genealogy has been documented. Armand-Jean de Mauvillain completed his medical studies in Paris and graduated on May 19, 1649. He was appointed "Docteur-régent" on Februrary 3, 1650 and professor of botany in 1655. He was dismissed from his position at the Faculté de médecine for four years due to a quarrel with the Dean Antoine Blondel. Then he resumed his former position and was elected Dean in 1666. In 1650, he married Gemme Cornuty the daughter of the "Docteur-régent" Jacques Cornuty and Anne Bergeret. Jacques Cornuty was the son of Georges Cornuty, a former Dean of the Faculté de médecine (1608-1610). Mauvillain and his wife had four children: Armand-Jean, also future "Docteur-régent", Guillaume, Nicolas and Louise-Angélique.His property inventory enables us to discover his living conditions, his collection of books and the value of his belongings. His role as Molière's counsellor is disputable. The actual date of his first meeting with the famous comedian has not been ascertained. The geneaology of de Mauvillain's family has been documented from the end of the sixteenth century to the middle of the eighteenth century. Its members counted a surgeon, a priest, physicians and lawyers. These commendable activities were in accordance with those traditionally practised by the Ancien Regime middle class members.

A Biographic Comparison Tracing the Similarities in the Lives of Jean Piaget and Lev Vygotsky.

ERIC Educational Resources Information Center

Pass, Susan

This paper focuses on similarities in the lives of Jean Piaget and Lev Vygotsky to enlighten study of their pedagogies and to provide some information for current classroom techniques. Neither man had a great deal to say about his early life, although Piaget published an autobiography. A number of primary sources were used to construct the…

A Biographic Comparison Tracing the Origin of Their Ideas of Jean Piaget and Lev Vygotsky.

ERIC Educational Resources Information Center

Pass, Susan

This paper compares the early life, background, and education of Jean Piaget and Lev Vygotsky. It makes the case that an adaptation of the curve developed by C. Quigley can be used to trace the motivations of both Piaget and Vygotsky in creating their respective theories. The analysis also reveals the adversity that each man faced. Although they…

The Role of Trustworthiness in Teaching: An Examination of "The Prime of Miss Jean Brodie"

ERIC Educational Resources Information Center

Katz, Michael S.

2014-01-01

The purpose of this paper is to examine the role that trustworthiness plays in the ability of teachers to function as moral role models. Through exploration of Muriel Spark's novel, "The Prime of Miss Jean Brodie," I explain some of the central features of trustworthiness as a moral virtue and suggest how these features are critical…

Astronaut Jean-Francois Clervoy in middeck during launch/entry training

NASA Image and Video Library

1994-06-23

S94-40081 (23 June 1994) --- Wearing a training version of a partial pressure suit, Jean-Francois Clervoy, STS-66 international mission specialist, secures himself on a collapsible seat on the middeck of a Shuttle trainer during a rehearsal of procedures to be followed during launch and entry phases of his scheduled November flight. This rehearsal, held in the Crew Compartment Trainer (CCT) of the Johnson Space Center's (JSC) Shuttle Mockup and Integration Laboratory, was followed by a training session on emergency egress procedures. Clervoy, a European astronaut, will join five NASA astronauts for a week and a half aboard the Space Shuttle Atlantis in Earth-orbit in support of the Atmospheric Laboratory for Applications and Science (ATLAS-3).

Reevaluation of Chalcophora angulicollis (LeConte) and Chalcophora virginiensis (Drury) with a review and key to the North American species of Chalcophora DeJean (Coleoptera: Buprestidae)

Treesearch

Crystal A. Maier; Michael A. Ivie

2013-01-01

Chalcophora angulicollis (LeConte) and Chalcophora virginiensis (Drury) are shown to be valid allopatric species in the western and eastern forests of North America, respectively. The historic uncertainty regarding their status is reviewed, and new characters of the aedeagus, penultimate maxillary palpomere, and elytral serrations are utilized for their identification...

A Portrait of the Teacher as Friend and Artist: The Example of Jean-Jacques Rousseau

ERIC Educational Resources Information Center

McEwan, Hunter

2011-01-01

The following is a reflection on the possibility of teaching by example, and especially as the idea of teaching by example is developed in the work of Jean-Jacques Rousseau. My thesis is that Rousseau created a literary version of himself in his writings as an embodiment of his philosophy, rather in the same way and with the same purpose that…

Near East/South Asia Report.

DTIC Science & Technology

1985-09-10

enclosed in parentheses. Words or names preceded by a ques - tion mark and enclosed in parentheses were hot clear in the original but have been supplied äs...Discussed (Jean de la Gueriviere; LE MONDE, 20 Jul 85) .. Motives of Algerian Human Rights League Questioned (ALGERIE ACTUALITE, 18-24 Jul 85...pp 1, 4 [Article by Algiers correspondent Jean de la Gueriviere: "Algeria or the Dif- ficult Serenity"] ;. [Text] Algeria, apparently wanting to

Le sevrage de l’allaitement

PubMed Central

Grueger, Barbara

2013-01-01

RÉSUMÉ L’allaitement exclusif assure une alimentation optimale aux nourrissons jusqu’à l’âge de six mois. Par la suite, les nourrissons ont besoin d’aliments complémentaires pour répondre à leurs besoins nutritionnels. C’est alors que le sevrage commence. Le sevrage désigne le processus graduel d’introduction d’aliments complémentaires au régime du nourrisson, tout en poursuivant l’allaitement. Il n’y a pas de moment universellement accepté ou scientifiquement démontré pour mettre un terme à l’allaitement. Le moment et le processus de sevrage doivent être adaptés par la mère et l’enfant. Le sevrage peut être soudain ou graduel, prendre plusieurs semaines ou plusieurs mois, être dirigé par l’enfant ou par la mère. Les médecins doivent orienter et soutenir les mères tout au long du processus de sevrage. Le présent document remplace le document de principes sur le sevrage qu’a publié la Société canadienne de pédiatrie en 2004.

Elementary Teachers' Application of Jean Piaget's Theories of Cognitive Development during Social Studies Curriculum Debates in Arizona

ERIC Educational Resources Information Center

Hinde, Elizabeth R.; Perry, Nancy

2007-01-01

In this article we explore educators' use of Jean Piaget's theories concerning cognitive development to refute proposed social studies standards in Arizona. We describe the work of Piaget as well as the National Association for the Education of Young Children's developmentally appropriate practices as they apply to primary-grade children's…

Jean-Jacques Rousseau on Adult Education and Revolution. Paradigma of Radical, Pedagogical Thought. 2nd Revised Edition.

ERIC Educational Resources Information Center

Dame, Frederick William

This book explores Jean-Jacques Rousseau's educational philosophy, as expressed in his key works, and applies that philosophy to adult education and revolution. The titles and topics of the book's seven chapters are as follows: (1) "L'Invitation: Raison d'Etre" (prelude, statement, significance, the process, assumptions and limitations);…

Le bégaiement

PubMed Central

Perez, Hector R.; Stoeckle, James H.

2016-01-01

Résumé Objectif Fournir une mise à jour sur l’épidémiologie, l’hérédité, la physiopathologie, le diagnostic et le traitement du bégaiement développemental. Qualité des données Une recherche d’études récentes ou non portant sur l’épidémiologie, l’hérédité, la physiopathologie, le diagnostic et le traitement du bégaiement développemental a été effectuée dans les bases de données MEDLINE et Cochrane. La plupart des recommandations s’appuient sur des études de petite envergure, des données probantes de qualité limitée ou des consensus. Message principal Le bégaiement est un trouble d’élocution fréquent chez les personnes de tous âges, il altère la fluidité verbale normale et l’enchaînement du discours. Le bégaiement a été lié à des différences de l’anatomie, du fonctionnement et de la régulation dopaminergique du cerveau qui seraient de source génétique. Il importe de poser le diagnostic avec attention et de faire les recommandations qui conviennent chez les enfants, car de plus en plus, le consensus veut que l’intervention précoce par un traitement d’orthophonie soit cruciale chez les enfants bègues. Chez les adultes, le bégaiement est lié à une morbidité psychosociale substantielle, dont l’anxiété sociale et une piètre qualité de vie. Les traitements pharmacologiques ont soulevé l’intérêt depuis quelques années, mais les données cliniques sont limitées. Le traitement des enfants et des adultes repose sur l’orthophonie. Conclusion De plus en plus de recherches ont tenté de lever le voile sur la physiopathologie du bégaiement. La meilleure solution pour les enfants et les adultes bègues demeure la recommandation à un traitement d’orthophonie.

Man with a Mission: Jean-Dominique Cassini

NASA Astrophysics Data System (ADS)

Belkora, Leila

2004-03-01

Jean-Dominique Cassini, for whom the Cassini mission to Saturn is named, is best known for his early understanding of that planet's rings. This article is an overview of his influential career in astronomy and other scientific fields.= Born in Italy in1625 and formally educated at an early age, he was a professor of astronomy at the University of Bologna, a leading center of learning in Europe of the time. He was an early observer of Jupiter, Mars, and Venus. He is best known for constructing a giant pinhole camera in a cathedral that he used with a meridian line on the floor to track the Sun's image through the year, thus providing the Catholic Church with a reliable calendar. Cassini also used the pinhole camera observations to calculate the variation in the distance between the Sun and Earth, thus lending support to the Copernican (Sun-centered) view of the solar system. Cassini moved to Paris at the request of King Louis XIV, originally to oversee the surveying needed for a new map system of France, but ultimately he took over as the director of the Paris Observatory. Cassini's descendants ran the observatory there for the following century.

[Jean-Louis-Paul Denucé (1824-1889): A forgotten pioneer of plastic surgery].

PubMed

Marck, K W; Martin, D

2016-02-01

The authors propose to define as main characterization of plastic reconstructive surgery the conceptual thinking that leads to a rational choice of an operative treatment. Conceptual thinking in plastic surgery started halfway the nineteenth century with the first schematic representations of the operative procedures available at that time, in which Von Ammon and Baumgarten, Szymanowski and Denucé played a prominent role. These four authors and their works are presented with special attention for the less known of them, Jean-Paul Denucé, surgeon in Bordeaux. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

[Albert-Jean-Louis Brun, pharmacist of Geneva and vulcanologist].

PubMed

Chaigneau, M

1996-01-01

Albert-Jean-Louis Brun (1851-1929), was chemist of the University of Bern (Switzerland) and "licencié ès sciences" of the University of Sorbonne (France). In Paris he was a faithful follower of Charles Friedel. In Coutance (Genève), where he was working in his own chemistry, he realised all his researchs. After a trip to Stromboli in 1901, he studied the volcanic phenomena as a chemist, as a mineralogist and as a geophysicist. His researchs brought him till the mediterranean volcanos--Vesuve, Etna, Santorin--, till Java and Krakatoa, then Canarian islands, and the lava lake of Kilauea, etc. The results of his works are collected in a big book called "Recherches sur l'exhalaison volcanique": he presents a theory which was the subject of a polemic with the professor Henri Gautier of the professor Henri Gautier of the Faculty of Pharmacy of Paris.

Le Laboratoire de Mécanique Appliquée Raymond Chaléat a 40 ans !

NASA Astrophysics Data System (ADS)

Comité D'Organisation Du Colloque Ime 2002, Le

2002-12-01

Le LMARC a été créé par Raymond Chaléat dans les locaux de l'École Nationale d'Horlogerie (a présent Lycée Technique Jules Haag).L'équipe de recherche était alors constituée de 2 enseignants-chercheurs (Raymond Chaléat et Gérard Lallement) et d'un technicien (Bernard Prêtre). Les travaux de recherche se situaient naturellement dans le domaine de la chronométrie et en particulier dans la mécanique non linéaire analytique inhérente à la montre en fonctionnement. En effet, Raymond Chaléat fut l'élève, puis le collaborateur du Professeur Jules Haag, mathématicien et mécanicien, lui-même élève de Poincarré.Le LMARC a étendu ses activités avec l'arrivée de Claude Oudet, puis de Claude Oytana à la rhéologie des matériaux solides qui est devenue plus tard l'Équipe Propriétés Mécaniques des Matériaux. En parallèle, G. Lallement a créé une équipe Vibrations devenue à ce jour Dynamique des Structures. À ce jour, le Laboratoire compte plus de 110 personnes dont 40 doctorants.Il a depuis diversifié ses activités avec 3 nouvelles équipes tournées vers la Modélisation et la Mise en Forme des Matériaux, les Micromachines et la Biomécanique et les Mécanismes. Il a su également prendre toute sa place au sein de l'Institut des Microtechniques de Franche-Comté en contribuant à plusieurs thèmes.Notre Laboratoire a été l'un des premiers laboratoires associé au CNRS (4ème) et a toujours été rattaché à l'Université de Franche-Comté (Présidence par C. Oytana de 1996 a 2001) par l'entremise de I'UFR Sciences et Techniques. Il a toujours maintenu des liens forts avec I'ENSMM (École Nationale Supérieure de Mécanique et des Microtechniques) d'une part par ses enseignants-chercheurs et d'autre part deux de ses directeurs, Raymond Chaléat et actuellement Jean-Claude Gelin.En plus de ses relations constantes avec l'industrie régionale, le LMARC a développé des actions contractuelles avec de grands groupes tels que EDF

Profile of a leader. Alena Jean MacMaster: administrator, educator, professional activist and community advocate.

PubMed

Gautreau, G; Winans, P

1999-01-01

This paper profiles Alena Jean MacMaster, an extraordinary nurse leader, activist, visionary and humanitarian from New Brunswick. Her determination and drive were instrumental in fostering the development and progression of health care, nursing education and nursing services at the local, provincial, federal and international levels. "First, loyalty to the institution in which you serve. The patient is the most important person in the entire institution," was Miss MacMaster's guiding principle throughout her career.

Historical Bibliography of Sea Mine Warfare

DTIC Science & Technology

1976-01-01

Sept. 1877. pp. 531-601. Auphan, Paul and Jacques Mordal; The French Navy in World War IT; U.S. Naval 14. Institute, 1959; Annapolis, Maryland. The...Queen Elizabeth; Time, Vol. XXXV, No. 12, Mar. 18, 1940; New York. pg. 27. 3. De Gouy, Jean Baptiste and C. R. Mathieu; Le Guerre Sous-AMarine de 1917...Payot and Co., 1918; Paris. 4. De Gouy, Jean Baptiste and C. R. Mathieu; Pour en Finir Avec les Souo- Marines; Payot and Co., 1918; Paris. 5

Jeans instability of inhomogeneous dusty plasma with polarization force, ionization and recombination

NASA Astrophysics Data System (ADS)

Jain, Shweta; Sharma, Prerana; Chhajlani, R. K.

2017-05-01

The self-gravitational Jeans instability has been studied in dusty plasma containing significant background of neutral pressure and recombination of ions and electrons on the dust surface. The full dynamics of charged dust grains, ions and neutral species are employed considering the electrons as Maxwellian. We have derived the general dispersion relation for collisional dusty plasma with ionization, recombination and polarization force. The general dispersion relation describes the effects of considered parameters which are solved in different dusty plasma situations. Further, the dispersion relation is solved numerically. The present work is applicable to understand the structure formation of interstellar molecular clouds in astrophysical plasma.

[Jean Martin Charcot and his controversial research on hysteria].

PubMed

von Plessen, K

1996-12-10

Jean Martin Charcot (1825-1893) is known as the founder of neurology in France and was one of the most versatile medical researchers of his times. At the climax of his career in the Salpêtrière in Paris he began to study the phenomenon of hysteria. Hysterical symptoms were very common in the late nineteenth century in Europe and were looked upon as a challenge to medical science. By means of accurate observation, Charcot managed to describe the distinct features of hysteria. The disease became an accepted medical entity and patients were less often regarded as simulators. Charcot presumed that the disease had a physical cause, and tried to prove this by means of patho-anatomical studies and later by experiment, with help of hypnosis. Charcot's despotic personality, the extraordinary circumstances at the Salpêtrière and the hysteric patients formed a fascinating setting that gives exemplary insight into the non-linear progress of medical science.

Impact de la varicocèle sur le volume testiculaire et les paramètres spermatiques

PubMed Central

Benazzouz, Mohamed Hicham; Essatara, Younes; El Sayegh, Hachem; Iken, Ali; Benslimane, Lounis; Nouini, Yassine

2014-01-01

Introduction La varicocèle est une pathologie masculine fréquente dont l'incidence est encore plus importante dans dans la population des hommes infertiles. Si ses mécanismes sont à ce jour incomplètement expliqués il semble acquis que la varicocèle peut être associée a une dysfonction testiculaire avec diminution du volume testiculaire et de la concentration en spermatozoïde de l’éjaculat. Méthodes Dans un premier temps nous exposons les résultats d'une étude rétrospective sur 5 ans (de Mars 2009 à Mars 2014), réalisée au service d'urologie A de l'hôpital Ibn Sina de Rabat et ayant comme objectif d’évaluer l'impact de la varicocèle palpable sur le volume testiculaire et les paramètres spermatiques. Tous les patients inclus dans notre étude avaient une varicocèle palpable. Dans un deuxième temps, et à travers une revue de la littérature nous discutons l'impact du traitement de la varicocèle sur la fertilité. Résultats 39 patients ont été inclus dans notre étude. L’âge moyen était de 29,71 ans et la varicocèle siégeait dans 89,74% des cas du coté gauche. Une atrophie testiculaire homolatérale à la varicocèle était retrouvée dans 7% des cas alors que des anomalies du spermogramme se voyaient dans 69,23% des cas. Conclusion L'impact de la varicocèle sur l'altération des paramètres spermatiques a été clairement établi bien que sa physio pathogénie ne soit pas bien élucidée. Le traitement chirurgical de la varicocèle semble indiqué chez les hommes infertiles présentant une varicocèle clinique et une altération significative du sperme. PMID:25918574

Beware of ligand efficiency (LE): understanding LE data in modeling structure-activity and structure-economy relationships.

PubMed

Polanski, Jaroslaw; Tkocz, Aleksandra; Kucia, Urszula

2017-09-11

On the one hand, ligand efficiency (LE) and the binding efficiency index (BEI), which are binding properties (B) averaged versus the heavy atom count (HAC: LE) or molecular weight (MW: BEI), have recently been declared a novel universal tool for drug design. On the other hand, questions have been raised about the mathematical validity of the LE approach. In fact, neither the critics nor the advocates are precise enough to provide a generally understandable and accepted chemistry of the LE metrics. In particular, this refers to the puzzle of the LE trends for small and large molecules. In this paper, we explain the chemistry and mathematics of the LE type of data. Because LE is a weight metrics related to binding per gram, its hyperbolic decrease with an increasing number of heavy atoms can be easily understood by its 1/MW dependency. Accordingly, we analyzed how this influences the LE trends for ligand-target binding, economic big data or molecular descriptor data. In particular, we compared the trends for the thermodynamic ∆G data of a series of ligands that interact with 14 different target classes, which were extracted from the BindingDB database with the market prices of a commercial compound library of ca. 2.5 mln synthetic building blocks. An interpretation of LE and BEI that clearly explains the observed trends for these parameters are presented here for the first time. Accordingly, we show that the main misunderstanding of the chemical meaning of the BEI and LE parameters is their interpretation as molecular descriptors that are connected with a single molecule, while binding is a statistical effect in which a population of ligands limits the formation of ligand-receptor complexes. Therefore, LE (BEI) should not be interpreted as a molecular (physicochemical) descriptor that is connected with a single molecule but as a property (binding per gram). Accordingly, the puzzle of the surprising behavior of LE is explained by the 1/MW dependency. This effect

European National Society Cardiovascular Journals

PubMed Central

Alfonso, F.; Ambrosio, G.; Pinto, F.J.; van der Wall, E.E.

2008-01-01

Anesti Kondili MD, Djamaleddine Nibouche MD, Karlen Adamyan MD, Kurt Huber MD, Hugo Ector MD, Izet Masic MD, Rumiana Tarnovska MD, Mario Ivanusa MD, Vladimír Stane˘k MD, Jørgen Videbæk MD, Mohamed Hamed MD, Alexandras Laucevicius MD, Pirjo Mustonen MD, Jean-Yves Artigou MD, Ariel Cohen MD, Mamanti Rogava MD, Michael Böhm MD, Eckart Fleck MD, Gerd Heusch MD, Rainer Klawki MD, Panos Vardas MD, Christodoulos Stefanadis MD, József Tenczer MD, Massimo Chiariello MD, Aleksandras Laucevicius MD, Joseph Elias MD, Halima Benjelloun MD, Olaf Rødevand MD, Piotr Kul/akowski MD, Edvard Apetrei MD, Victor A. Lusov MD, Rafael G. Oganov MD, Velibor Obradovic MD, Gabriel Kamensky MD, Miran F. Kenda MD, Christer Höglund MD, Thomas F. Lüscher MD, René Lerch MD, Moufid Jokhadar MD, Habib Haouala MD, Vedat Sansoy MD, Valentin Shumakov MD, Adam Timmis MD. (European National Society Cardiovascular Journals Editors, see Appendix for complete affiliations) PMID:18665206

Jean Baptiste Paulin Trolard (1842-1910): his life and contributions to neuroanatomy.

PubMed

Loukas, Marios; Shea, Misha; Shea, Cory; Lutter-Hoppenheim, Martine; Zand, Paula; Tubbs, R Shane; Cohen-Gadol, Aaron A

2010-06-01

One hundred years after his death, Jean Baptiste Paulin Trolard's name endures in the medical literature primarily because of his work on the anastomotic veins of the cerebral circulation. Specifically, and known to all neurosurgeons, the great anastomotic vein, or the vein of Trolard, underscores a portion of Trolard's contribution to neuroanatomy. The country of Algeria has also remembered this influential colonist because of his life's work as a physician, professor, humanitarian, environmentalist, and French nationalist. Trolard fought deforestation, injustice, epidemics, and bureaucracy in northern Africa and tragically died in the midst of these struggles. In this historical vignette, the authors review the life and contributions of this pioneer of early neuroanatomy.

Energy levels, wavelengths, and radiative transition probabilities for the Na-like ions with 38 [le] Z [le] 45

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ying Zhang; Qiren Zhu; Shoufu Pan

1992-11-01

The investigation by Z.-Q Zhang et al. (Acta Optica Sinica 11, 193, 1991) shows that it is possible to realize soft X-ray lasing in the water window 23.3-43.8 [Angstrom] with the Na-like recombination scheme, which requires a lower pumping power at a high-power laser facility than that with other schemes. The fine-structure levels with n [le] 15 and l [le] 6 in Na-like ions with 38 [le] Z [le] 45 and the probabilities for radiative transitions between these levels are calculated using the multiconfiguration Dirac-Fock approach. The calculations show that the wavelengths of the anticipated laser transitions 6 f-4d andmore » 6g-4f in the Na-like ions with 38 [le] Z [le] 43 and 5f-4d and 5g-4f in the Na-like ions with 40 [le] Z [le] 45 lie in the region of the water window.« less

Cooperation or Competition? The American and French Foreign Policies in Africa (Cooperation ou concurrence? La politique africaine de la France et des Etats-Unis en Afrique sub-saharienne)

DTIC Science & Technology

2005-07-26

Villepin, appelle « des conflits ancestraux >>, c’est-di-dire des conflits pour le contr6le de ressources primaires , ou de territoire, ou pour des diff~rends...traduira par une plus grande attention portde aux sujets africains et aussi d la part du budget pour l’Afrique. Le facteur religieux Les missionnaires en...grands avions de transport ou celles des soldats 6tablissant des centres de soins m6dicaux avec les ONG. Comme Jean-Paul Ngoupand6 l’a exprim6: << On

Biomechanical considerations for distraction of the monobloc, Le Fort III, and Le Fort I segments.

PubMed

Figueroa, Alvaro A; Polley, John W; Figueroa, Aaron D

2010-09-01

Distraction osteogenesis is effective for correction of severe maxillary and midface hypoplasia. The vectors controlling the segment to be moved must be planned. This requires knowledge of the physical characteristics of the osteotomized bone segment, including the location of the center of mass (free body) and the center of resistance (restrained body). The purpose of this study was to determine the center of mass of the osteotomized monobloc, Le Fort III, and Le Fort I bone segments. A dry human skull was used to sequentially isolate three bone segments: monobloc, Le Fort III, and Le Fort I. Each segment was suspended from three different points, and digital photographs were obtained from each suspension. The photographs were digitally superimposed. The center of mass was determined by calculating the intersection of the suspension lines. The center of mass for the monobloc segment was located at a point 43.5 percent of the total height from the occlusal plane to the superior edge of the frontal bone supraorbital osteotomy. For the Le Fort III, it was located 38 percent of the total height from the occlusal plane to the superior edge of the osteotomized base of the nasal bones. For the Le Fort I, it was 53 percent of the total height from the occlusal plane to the superior edge of the osteotomized maxillary bone. Knowledge of the location of the center of mass in the monobloc, Le Fort III, and Le Fort I segments provides a starting point for the clinician when planning vectors for advancement with distraction.

Jean Marian Purdy remembered - the hidden life of an IVF pioneer.

PubMed

Gosden, Roger

2018-06-01

Jean Purdy is almost forgotten as one of the British trio that introduced clinical IVF to the world. An unlikely pioneer, she qualified as a nurse but through indefatigable effort and unstinting loyalty to a programme that faced vitriolic opposition she became the clinical embryologist for the first IVF baby. In 1980, she helped to launch fertility services as the 'Technical Director' of Bourn Hall Clinic, near Cambridge. Although Robert Edwards and Patrick Steptoe generously credited her role in research and clinical care, a premature death in 1985 at age 39 robbed her of the reward of witnessing the blossoming of assisted reproductive technologies for patients around the world. This commentary seeks to recognize her contribution and bring her name to the attention of professionals in reproductive medicine and the patients they care for.

[Jean-Martin Charcot (1825-1893): a physician with multiple facets].

PubMed

Lellouch, Alain

2013-12-01

This work is registered in the year (2013) commemorating the 120 years since Jean-Martin Charcot's (1825-1893) death. Presently, the event takes place during 2013, in France, in Paris, at Hôpital de la Salpêtrière where Charcot practiced as medical chief of l'Hospice de la Vieillesse-Femmes, from 1862 until he died in 1893. The aim of the research is to show, from various examples and sources (printed and handwritten: fonds d'archives Charcot de la Salpêtrière) how talented Charcot was as a clinician, pathologist and microscopist, researcher and experimenter, teacher, artist, designer, cartoonist, polyglot and traveller), how varied his medical career was and how innovative his scientific method was. All this permitted Charcot to make an impressive number of medical discoveries in various fields which are today known as geriatrics and rheumatology, internal medicine, cardiology, neurology, psychiatry and paranormal processes.

Jean Langlais (1907-91): an historical case of a blind organist with stroke-induced aphasia and Braille alexia but without amusia.

PubMed

Fisher, C A H; Larner, A J

2008-11-01

The subject of a prior report of a blind organist with aphasia and Braille alexia without amusia, published in French, has been identified as Jean Langlais. His artistic and medical history is presented, the latter via translation of the original 1987 paper.

Cosmological implications of a stellar initial mass function that varies with the Jeans mass in galaxies

NASA Astrophysics Data System (ADS)

Narayanan, Desika; Davé, Romeel

2012-07-01

Observations of star-forming galaxies at high z have suggested discrepancies in the inferred star formation rates (SFRs) either between data and models or between complementary measures of the SFR. These putative discrepancies could all be alleviated if the stellar initial mass function (IMF) is systematically weighted towards more high-mass star formation in rapidly star-forming galaxies. Here, we explore how the IMF might vary under the central assumption that the turnover mass in the IMF, ?, scales with the Jeans mass in giant molecular clouds (GMCs), ?. We employ hydrodynamic simulations of galaxies coupled with radiative transfer models to predict how the typical GMC Jeans mass, and hence the IMF, varies with galaxy properties. We then study the impact of such an IMF on the star formation law, the SFR-M* relation, sub-millimetre galaxies (SMGs) and the cosmic SFR density. Our main results are: the H2 mass-weighted Jeans mass in a galaxy scales well with the SFR when the SFR is greater than a few M⊙ yr-1. Stellar population synthesis modelling shows that this results in a non-linear relation between SFR and Lbol, such that SFR ?. Using this model relation, the inferred SFR of local ultraluminous infrared galaxies decreases by a factor of ˜2, and that of high-z SMGs decreases by a factor of ˜3-5. At z˜ 2, this results in a lowered normalization of the SFR-M* relation in better agreement with models, a reduced discrepancy between the observed cosmic SFR density and stellar mass density evolution, and SMG SFRs that are easier to accommodate in current hierarchical structure formation models. It further results in a Kennicutt-Schmidt star formation law with a slope of ˜1.6 when utilizing a physically motivated form for the CO-H2 conversion factor that varies with galaxy physical property. While each of the discrepancies considered here could be alleviated without appealing to a varying IMF, the modest variation implied by assuming ? is a plausible solution

CONSTRAINTS ON THE SHAPE OF THE MILKY WAY DARK MATTER HALO FROM JEANS EQUATIONS APPLIED TO SLOAN DIGITAL SKY SURVEY DATA

DOE Office of Scientific and Technical Information (OSTI.GOV)

Loebman, Sarah R.; Ivezic, Zeljko; Quinn, Thomas R.

2012-10-10

We search for evidence of dark matter in the Milky Way by utilizing the stellar number density distribution and kinematics measured by the Sloan Digital Sky Survey (SDSS) to heliocentric distances exceeding {approx}10 kpc. We employ the cylindrically symmetric form of Jeans equations and focus on the morphology of the resulting acceleration maps, rather than the normalization of the total mass as done in previous, mostly local, studies. Jeans equations are first applied to a mock catalog based on a cosmologically derived N-body+SPH simulation, and the known acceleration (gradient of gravitational potential) is successfully recovered. The same simulation is alsomore » used to quantify the impact of dark matter on the total acceleration. We use Galfast, a code designed to quantitatively reproduce SDSS measurements and selection effects, to generate a synthetic stellar catalog. We apply Jeans equations to this catalog and produce two-dimensional maps of stellar acceleration. These maps reveal that in a Newtonian framework, the implied gravitational potential cannot be explained by visible matter alone. The acceleration experienced by stars at galactocentric distances of {approx}20 kpc is three times larger than what can be explained by purely visible matter. The application of an analytic method for estimating the dark matter halo axis ratio to SDSS data implies an oblate halo with q{sub DM} = 0.47 {+-} 0.14 within the same distance range. These techniques can be used to map the dark matter halo to much larger distances from the Galactic center using upcoming deep optical surveys, such as LSST.« less

La Vie Politique sous la Restauration a Travers ’Le Rouge et le Noir’ de Stendahl (The Political Life during the Restauration as Depicted in Le Rouge et le Noir by Stendahl)

DTIC Science & Technology

1989-01-01

de la classe dirigeante est le clerg6. M. le vicaire de Frilair est le bras droit de l ’&veque dle Besangon et...sympathique effort de recherche ;la documentation contribue bien A 6clairer lanalyse. INTERPRETATION: L 𔄀tude des aspects de la vie politique sous la...References Ouvrages consultes AXccesion For NTIS CRA&I DTIC TA9 El Unanno ’-,’ 1 : By 442.-. - L -- A, _ojes Aof -d/or * A- Dans l’L*tude des

Le continu contre l'espace

NASA Astrophysics Data System (ADS)

Salanskis, Jean-Michel

Disons pour conclure que, en tout état de cause, la façon de concevoir philosophiquement le conflit du continu et de l'espace que nous avons trouvée chez Hegel n'est pas homogène avec le style et les modalités de la pensée mathématique: 1) d'une part, le lien classique, le lien de référence entre continu et espace en mathématiques n'est pas que l'espace serait premier et privé de pensée, et le continu second, venant dissoudre l'espace en apportant la qualité, l'infini et la pensée, mais tout au contraire, il consiste en ce que l'espace est fondé sur l'abîme infinitaire du continu ; 2) d'autre part, l'éventuel divorce entre l'espace et le continu dans l'aire mathématique n'est pas celui d'une réflexivité purement conceptuelle du continu avec un positivisme géométrique, n'équivaut pas à une rupture disciplinaire ; il est plutôt le symptôme de la dérive d'une herméneutique à l'égard d'une autre, au sein d'un continent juridique commun définissant la discipline (la mathématique ensembliste), cette dérive pouvant, à la limite, induire une refonte de ce sol juridique, sans que jamais il soit question pour autant de nier l'unité des mathématiques, à comprendre ici comme l'unité ultime de responsabilité de la communauté mathématique à l'égard des trois questions Qu'est-ce que l'espace?”, “Qu'est-ce que le continu?” et “Qu'est-ce que l'infini?”.

Analysis of Jeans instability of optically thick quantum plasma under the effect of modified Ohms law

NASA Astrophysics Data System (ADS)

Pensia, R. K.; Sutar, D. L.; Sharma, S.

2018-05-01

The Jeans instability of self-gravitating optically thick quantum plasma is reanalyzed in the framework of viscosity, black body radiation and modify ohms law. The usual magnetohydrodynamic (MHD) equation is used for the present configuration with black body radiation, viscosity, electrical resistivity and quantum corrections. A general dispersion relation is obtained with the help of linearized perturbation equations. It is found that the quantum correction has stabilizing effect on the system. The instability of system is discussed for various cases as our interest.

Le rôle de l’omalizumab dans le traitement de l’asthme allergique grave

PubMed Central

Chapman, Kenneth R; Cartier, André; Hébert, Jacques; McIvor, R Andrew; Schellenberg, R Robert

2006-01-01

CONTEXTE : Un nouveau traitement anti-immunoglobuline E (anti-IgE) contre l’asthme, l’omalizumab, a été approuvé au Canada. OBJECTIF : Passer en revue les données fondamentales et cliniques sur l’omalizumab et examiner le rôle possible de ce médicament dans la prise en charge de l’asthme au Canada. MÉTHODOLOGIE : Une recherche documentaire a été effectuée dans MEDLINE afin de repérer les études menées de 1960 à 2006 sur l’omalizumab. La recherche a également porté sur les résumés de réunions scientifiques récentes dans le domaine des maladies respiratoires et des allergies; par ailleurs, toute donnée non publiée a été demandée au fabricant. Après avoir revu et résumé les données, un comité mixte constitué de spécialistes des maladies respiratoires et des allergies a rédigé un ensemble de recommandations relatives à l’utilisation de l’omalizumab. RÉSULTATS : L’omalizumab est un anticorps monoclonal humanisé qui se lie au domaine C epsilon 3 de la molécule d’IgE pour former des complexes immuns solubles qui sont éliminés par le système réticulo-endothélial. L’administration d’injections sous-cutanées espacées de deux ou de quatre semaines à la dose recommandée entraîne une diminution rapide des taux d’IgE circulantes libres. Lors de deux essais cliniques de phase III menés auprès de 1 405 adultes et adolescents atteints d’asthme modéré à grave qui recevaient des doses moyennes stables de corticostéroïdes en inhalation (CSI), l’omalizumab a diminué les taux d’exacerbation par rapport au placebo et a été associé à une amélioration des symptômes ainsi qu’à une épargne plus importante des corticostéroïdes. Dans un essai mené auprès de 419 patients atteints d’asthme grave non maîtrisé malgré l’utilisation de doses élevées de CSI et de la prise concomitante d’agonistes bêta-2 à action prolongée, les exacerbations graves étaient de 50 % moins fréquentes chez

Human rights assessment in Parc Jean Marie Vincent, Port-au-Prince, Haiti.

PubMed

Cullen, Kimberly A; Ivers, Louise C

2010-12-15

Months after a 7.0 magnitude earthquake hit Port-au-Prince, Haiti, over one million remain homeless and living in spontaneous internally displaced person (IDP) camps. Billions of dollars from aid organizations and government agencies have been pledged toward the relief effort, yet many basic human needs, including food, shelter, and sanitation, continue to be unmet. The Sphere Project, "Humanitarian Charter and Minimum Standards in Disaster Response," identifies the minimum standards to be attained in disaster response. From a human rights perspective and utilizing key indicators from the Sphere Project as benchmarks, this article reports on an assessment of the living conditions approximately 12 weeks after the earthquake in Parc Jean Marie Vincent, a spontaneous IDP camp in Port-au-Prince. A stratified random sample of households in the camp, proportionate to the number of families living in each sector, was selected. Interview questions were designed to serve as "key indicators" for the Sphere Project minimum standards. A total of 486 interviews were completed, representing approximately 5% of households in each of the five sectors of the camp. Our assessment identified the relative achievements and shortcomings in the provision of relief services in Parc Jean Marie Vincent. At the time of this survey, the Sphere Project minimum standards for access to health care and quantity of water per person per day were being met. Food, shelter, sanitation, and security were below minimum accepted standard and of major concern. The formal assessment reported here was completed by September 2010, and is necessarily limited to conditions in Haiti before the cholera outbreak in October. Copyright © 2010 Cullen and Ivers. This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any

NOMENCLATURAL NOTES ON THE EURYTOMIDS (CHALCIDOIDEA: EURYTOMIDAE) DESCRIBED BY JEAN BRÈTHES HOUSED IN MUSEO ARGENTINO DE CIENCIAS NATURALES “BERNARDINO RIVADAVIA”

USDA-ARS?s Scientific Manuscript database

Nine species parasitic eurytomid wasps described by Jean Brèthes and deposited in the National Insect Collection of Argentina, Buenos Aires are treated and their nomenclature stabilized. The condition of the type material is described. Lectotypes are designated for Prodecatoma parodii, Eudecatoma o...

Cavitation erosion in blocked flow with a ducted ice-class propeller

DOE Office of Scientific and Technical Information (OSTI.GOV)

Doucet, J.M.; Bose, N.; Walker, D.

1996-12-31

Ships that operate in ice often encounter momentary increased propeller cavitation because ice pieces block the flow into the propeller. For ducted propellers, this additional cavitation is more significant than it is for open propellers; ice pieces may become lodged against and within the duct and subject the propeller to longer periods of increased cavitation due to the blocked flow. Associated with this blocked flow is the possibility of cavitation erosion on the propeller. An erosion study, using paint films, was conducted in a cavitation tunnel with a model propeller of the type fitted to the Canadian Marine Drilling Ltd.more » vessel MV Robert LeMeur. A simulated ice blockage was installed ahead of the propeller model and within the duct. Tests were carried out over a range of advance coefficients for various test conditions. The resulting types of cavitation were documented, the erosion patterns were photographed and comparisons between each test were made.« less

From poolside, astronaut candidates Jean-Francois Clervoy (left) and Koichi Wakata watch as an

NASA Technical Reports Server (NTRS)

1996-01-01

1992 ASCAN TRAINING --- From poolside, astronaut candidates Jean-Francois Clervoy (left) and Koichi Wakata watch as an instructor (out of view) conducts a demonstration during a water survival training course at the Pensacola Naval Air Station in Florida. Clervoy (European Space Agency) and Wakata (Japan's National Space Development Agency) are among seven international mission specialist candidates who joined 19 United States astronaut candidates for the three-day parachute/survival training school at the Oklahoma Base. EDITORS NOTE: Since this photograph was taken, Clervoy has been named as mission specialist for STS-66 and Wakata has assigned duty as mission specialist for the STS-72 mission.

"I would eagerly leave Neuchâtel ..." A 1912 letter by Jean Piaget with an introduction and notes.

PubMed

Vidal, F

1986-01-01

A 1912 letter from fifteen-year-old Jean Piaget (1896-1980) to the director of the Museum of Natural History of Geneva illustrates Piaget's precocious integration into a community of professional naturalists, and reveals his hitherto unknown plan to study medicine. It is not certain whether he actually intended to realize that plan. An essential biographical fact, however, is that he finally left natural history by turning to philosophy rather than to medicine.

Le LHC, un tunnel cosmique

DOE Office of Scientific and Technical Information (OSTI.GOV)

Binetruy, Pierre

2009-09-17

Et si la lumière au bout du tunnel du LHC était cosmique ? En d’autres termes, qu’est-ce que le LHC peut nous apporter dans la connaissance de l’Univers ? Car la montée en énergie des accélérateurs de particules nous permet de mieux appréhender l’univers primordial, chaud et dense. Mais dans quel sens dit-on que le LHC reproduit des conditions proches du Big bang ? Quelles informations nous apporte-t-il sur le contenu de l’Univers ? La matière noire est-elle détectable au LHC ? L’énergie noire ? Pourquoi l’antimatière accumulée au CERN est-elle si rare dans l’Univers ? Et si le CERNmore » a bâti sa réputation sur l’exploration des forces faibles et fortes qui opèrent au sein des atomes et de leurs noyaux, est-ce que le LHC peut nous apporter des informations sur la force gravitationnelle qui gouverne l’évolution cosmique ? Depuis une trentaine d’années, notre compréhension de l’univers dans ses plus grandes dimensions et l’appréhension de son comportement aux plus petites distances sont intimement liées : en quoi le LHC va-t-il tester expérimentalement cette vision unifiée ? Tout public, entrée libre / Réservations au +41 (0)22 767 76 76« less

L'astronomie dans le monde

NASA Astrophysics Data System (ADS)

Manfroid, J.

2008-09-01

Fragmentation et astéroïdes binaires; Astéroïde géocroiseur triple; Rosetta sort de son hibernation; Messenger; Transit lunaire vu par Deep Impact; Titan; Phobos; Phoenix; Einstein avait raison; Le ballet des taches rouges; Le poids des lentilles;

Entrevue avec le Dr Charley Zeanah

PubMed Central

2013-01-01

Le Dr Charles Zeanah est titulaire de la chaire de psychiatrie Mary K. Sellars-Polchow, professeur de pédiatrie clinique et vice-président de la pédopsychiatrie au département de psychiatrie et des sciences du comportement de la faculté de médecine de l’Université Tulane, à la Nouvelle-Orléans. Il est également directeur général de l’institut de la santé mentale des nourrissons et des jeunes enfants de Tulane. Il est récipiendaire de nombreux prix, notamment le prix de prévention Irving Phillips (AACAP), la mention élogieuse présidentielle pour sa recherche et son leadership exceptionnels en santé mentale des nourrissons (American Orthopsychiatric Association), le prix d’excellence clinique Sarah Haley Memorial (International Society for Traumatic Stress Studies), le prix de recherche en pédopsychiatrie Blanche F. Ittelson (APA), et le prix Serge Lebovici Award soulignant les contributions internationales à la santé mentale des nourrissons (World Association for Infant Mental Health). Le Dr Zeanah est fellow distingué de l’AACAP, fellow distingué de l’APA et membre du conseil d’administration de Zero to Three. Il est l’éditeur scientifique de Handbook of Infant Mental Health (3e édition) qui est considéré comme étant le manuel de pointe et la référence de base du domaine de la santé mentale des nourrissons.

Transitory Connections: The Reception and Rejection of Jean Piaget's Psychology in the Nursery School Movement in the 1920s and 1930s

ERIC Educational Resources Information Center

Beatty, Barbara

2009-01-01

In 1927, nursery school educator Lucy Sprague Mitchell heralded Jean Piaget's psychology as of "outstanding interest" and wrote in "Progressive Education" that it should be of "immense service" to psychologists, teachers, and parents. In 1929, psychologist Lois Meek praised Piaget's research in the National Society for the Study of Education's…

Antoine-Marie Chambeyron (1797-1851): a forgotten disciple of Jean-Etienne Esquirol (1772-1840).

PubMed

Walusinski, Olivier

2017-09-01

Antoine-Marie Chambeyron (1797-1851) was a disciple of Jean-Etienne Esquirol (1772-1840) that history forgot, undoubtedly because he made no original contribution to psychiatric nosography. In 1827, his interest in the medical-legal status of the insane led him to translate into French and annotate the first medical-legal psychiatric treatise ever published, which was the work of the German philosopher Johann Christoph Hoffbauer (1766-1827). His translation played a role in shaping the French Law of 1838, the first piece of modern legislation aimed at protecting the rights of mental patients and limiting the State's power to confine them arbitrarily. Chambeyron is among the least-cited contributors to the prestigious work of nineteenth-century French alienists.

Simultaneous transgenic suppression of LePG and LeExp1 influences fruit texture and juice viscosity in a fresh market tomato variety.

PubMed

Powell, Ann L T; Kalamaki, Mary S; Kurien, Philip A; Gurrieri, Sergio; Bennett, Alan B

2003-12-03

Tomatoes are grown for fresh consumption or for processing of the fruit. Some ripening-associated processes of the fruit can either contribute to or degrade attributes associated with both fresh and processing quality. For example, cell wall disassembly is associated with loss of fresh fruit firmness as well as with loss of processed tomato product viscosity. Several enzymes contribute to cell wall polysaccharide disassembly. Polygalacturonase (PG, poly[1,4-alpha-d-galactouronide] glucanohydrolase, EC 3.2.1.15) is among the most abundant polysaccharide hydrolases in ripening tomato fruit and is the major contributor to pectin depolymerization. Expansin (LeExp1) is also abundant in ripening fruit and is proposed to contribute to cell wall disassembly by nonhydrolytic activity, possibly by increasing substrate accessibility to other enzymes. Suppression of either LePG or LeExp1 expression alone results in altered softening and/or shelf life characteristics. To test whether simultaneous suppression of both LePG and LeExp1 expression influences fruit texture in additive or synergistic ways, transgenic Lycopersicon esculentum var. Ailsa Craig lines with reduced expression of either LePG or LeExp1 were crossed. Fruits from the third generation of progeny, homozygous for both transgenic constructs, were analyzed for firmness and other quality traits during ripening on or off the vine. In field-grown transgenic tomato fruit, suppression of LeExp1 or LePG alone did not significantly increase fruit firmness. However, fruits suppressed for both LePG and LeExp1 expression were significantly firmer throughout ripening and were less susceptible to deterioration during long-term storage. Juice prepared from the transgenic tomato fruit with reduced LePG and LeExp1 expression was more viscous than juice prepared from control fruit.

Jean Baudrillard's Radical Thinking, and Its Potential Contribution to the Sociology of Higher Education Illustrated by Debates about "World-Class" Universities

ERIC Educational Resources Information Center

Blanco Ramírez, Gerardo

2016-01-01

This article presents an argument for re-reading Jean Baudrillard's ideas considering their potential contribution to the sociology of higher education, particularly in relation to contemporary debates about "world-class" universities. In order to apply Baudrillard's ideas, China's commitment to the development of "world-class"…

Le Laser A Argon Ionise : Applications Therapeutiques

NASA Astrophysics Data System (ADS)

Brunetaud, J. M.; Mosquet, L.; Mordon, S.; Rotteleur, G.

1984-03-01

Le laser a argon ionise est un laser a emission continue, reglee en general en multiraies de 487 a 544 nm. Le rayonnement de ce laser est bien absorbe par les tissus vivants, avec une action preferentielle au niveau des pigments rouges (hemoglobine, myoglobine) et noirs (melanine). Le laser a argon est princi-palement utilise en therapeutique pour ses effets thermiques : en fonction du choix des parametres (puissance optique, surface exposee, temps d'exposition) on peut obtenir une coagulation (temperature optimale au niveau des tissus 60° - 80°) ou une volatisation (temperature superieure a 100°). Si la zone volatilisee est tres etroite (inferieure a 0,5 mm) on obtient un effet de coupe. Par rapport aux deux autres lasers egalement utilises pour leurs effets thermiques (CO2 et Nd. YAG) l'argon a des effets intermediaires : la coagulation sera plus superficielle qu'avec le Nd. YAG et la volatisation plus profonde qu'avec le CO2. Lors de la coupe, la necrose sur les berges sera egalement plus importante qu'avec le CO2.

Le Fort Fractures: A Collective Review

PubMed Central

Phillips, Bradley J.; Turco, Lauren M.

2017-01-01

Le Fort fractures constitute a pattern of complex facial injury that occurs secondary to blunt facial trauma.  The most common mechanisms of injury for these fractures, which are frequently associated with drug and alcohol use, include motor vehicle collisions, assault, and falls. A thorough search of the world’s literature following PRISMA guidelines was conducted through PubMed and EBSCO databases. Search terms included “Le Fort fracture”, “facial”, “craniofacial”, and “intracranial.”  Articles were selected based on relevance and examined regarding etiology, epidemiology, diagnosis, treatment, complications, and outcomes in adults. The analyzed studies were published between 1980 and 2016. Initial data search yielded 186 results. The search was narrowed to exclude articles lacking in specificity for Le Fort fractures.  Fifty-one articles were selected, the majority of which were large case studies, and collectively reported that Le Fort fractures are most commonly due to high-velocity MVC and that the severity of fracture type sustained occurred with increasing frequency.  It was also found that there is a general lack of published Level I, Level II, and Level III studies regarding Le Fort fracture management, surgical management, and outcomes. The limitation of this study, similar to all PRISMA-guided review articles, is the dependence on previously published research and availability of references as outlined in our methodology. While mortality rates for Le Fort fractures are low, these complex injuries seldom occur in isolation and are associated with other severe injuries to the head and neck. Quick and accurate diagnosis of Le Fort fractures and associated injuries is crucial to the successful management of blunt head trauma. PMID:29177168

Dissociative identity disorder: a feminist approach to inpatient treatment using Jean Baker Miller's Relational Model.

PubMed

Riggs, S R; Bright, M A

1997-08-01

Women diagnosed with Dissociative Identity Disorder (DID) may experience episodic crises characterized by intense states of disconnection from self and others. Crises which result in potential harm to self/others may require inpatient treatment. With economic emphasis on shorter lengths of stay, a treatment program or model which focuses on the DID patient's sense of connectedness to self and others can enhance treatment efforts during brief inpatient hospitalizations. The Relational Model of Jean Baker Miller uses mutuality and empowerment within the therapeutic relationship and inpatient mileu to move the patient beyond therapeutic impasse/crisis toward a state of greater connectedness to self and others.

Le syndrome d’alcoolisme foetal

PubMed Central

2002-01-01

L’alcool est un tératogène physique et comportemental. Le syndrome d’alcoolisme foetal (SAF) est un trouble courant mais encore sous-diagnostiqué découlant de la consommation d’alcool par la mère pendant la grossesse. Bien qu’il puisse être prévenu, le SAF est également invalidant. Même si le SAF est présent dans tous les groupes socioéconomiques du Canada, sa prévalence est élevée dans certaines communautés inuites et des Premières nations du Canada. Le présent énoncé porte sur la prévention, le diagnostic, le dépistage précoce et la prise en charge du SAF par les professionnels de la santé. La prévention du SAF doit s’effectuer à deux échelons. La prévention primaire consiste à éliminer le SAF par une formation en classe ou dans la collectivité et à inciter les femmes à éviter de consommer de l’alcool avant la conception et pendant la grossesse. La prévention secondaire consiste à repérer les femmes qui boivent pendant leur grossesse et à réduire leur consommation. Le présent énoncé décrit plusieurs stratégies de dépistage, dont la stratégie T-ACE (tolérance-agacement, réduction, éveil). Les dispensateurs de soins devraient recommander l’abstinence dès la première visite prénatale. Un envoi rapide en consultation en vue de traiter l’alcoolisme est recommandé pour les femmes enceintes incapables d’arrêter de boire. Le présent énoncé décrit le diagnostic de SAF, de SAF partiel ou atypique, d’anomalies congénitales et de troubles neurodéveloppementaux reliés à l’alcool. En cas d’exposition à l’alcool in utero, un diagnostic de SAF devrait être envisagé en présence d’un retard de croissance courant ou antérieur, de certaines anomalies faciales touchant la lèvre supérieure et les yeux et d’anomalies neurodéveloppementales. Ces caractéristiques sont mieux quantifiées au moyen d’une méthode diagnostique à quatre chiffres. Des stratégies de dépistage précoce des

Preface: Phonons 2007

NASA Astrophysics Data System (ADS)

Perrin, Bernard

2007-06-01

range using coloured picosecond ultrasonics). Both prizes were offered by C'Nano IdF (Centre de Compétence NanoSciences Ile-de-France/Paris District Competence Center in Nanosciences). I want also to point out the strong support given by three institutions: CNRS (Centre National de la Recherche Scientifique), INSP (Institut des NanoSciences de Paris) and SFA (Socitété Française d'Acoustique). Finally, I would like to thank the members of the different committees who helped for the organization of this conference. I am particularly indebted to Bernard Bonello, Arnaud Devos, Jean-Yves Duquesne, Jean-Yves Prieur and Clément Rossignol for their invaluable help. I appreciated the kindness and efficiency of Armelle Guilloux ('Ellipse & Co'). I want also to express my thanks to close collaborators: Catherine Dematteis, Agnès Huynh and Emmanuel Péronne. During the conference, I appreciated the valuable assistance of Sandrine Guit, Béatrice Desoudin and of the student team. The edition of these proceedings could not have been possible without the tremendous amount of work performed by Jean-Yves Duquesne and the valuable help of Jean-Yves Prieur. I hope that the delegates of PHONONS 2007 enjoyed the program and will be willing to attend the 13th conference which will be chaired by Professor Chi Kuang Sun in Taiwan in 2010. Bernard Perrin, Chairman of PHONONS 2007 Institut des NanoSciences de Paris, Paris, November 2007 Copyright: CNRS Photo - Nicole TIGET. The PDF contains the lists of committee members, sponsors and participants.

Le LHC, un tunnel cosmique

ScienceCinema

None

2017-12-09

Et si la lumière au bout du tunnel du LHC était cosmique ? En d’autres termes, qu’est-ce que le LHC peut nous apporter dans la connaissance de l’Univers ? Car la montée en énergie des accélérateurs de particules nous permet de mieux appréhender l’univers primordial, chaud et dense. Mais dans quel sens dit-on que le LHC reproduit des conditions proches du Big bang ? Quelles informations nous apporte-t-il sur le contenu de l’Univers ? La matière noire est-elle détectable au LHC ? L’énergie noire ? Pourquoi l’antimatière accumulée au CERN est-elle si rare dans l’Univers ? Et si le CERN a bâti sa réputation sur l’exploration des forces faibles et fortes qui opèrent au sein des atomes et de leurs noyaux, est-ce que le LHC peut nous apporter des informations sur la force gravitationnelle qui gouverne l’évolution cosmique ? Depuis une trentaine d’années, notre compréhension de l’univers dans ses plus grandes dimensions et l’appréhension de son comportement aux plus petites distances sont intimement liées : en quoi le LHC va-t-il tester expérimentalement cette vision unifiée ? Tout public, entrée libre / Réservations au +41 (0)22 767 76 76

Le patrimoine astronomique provençal

NASA Astrophysics Data System (ADS)

Rous, M.; Figon, P.; Guyot, S.

2012-12-01

L'OSU OAMP/Institut Pythéas porte les missions de conservation, inventaire et valorisation du patrimoine. Suite à la fusion de l'Observatoire de Marseille et du Laboratoire d'Astronomie Spatiale en 2000 pour créer le Laboratoire d'Astrophysique de Marseille, le déménagement des équipes sur le site de Château-Gombert en 2008 a soulevé le problème du devenir des collections des deux sites d'origine. Nous ferons le bilan des actions passées en matière de conservation et de valorisation de ce riche patrimoine : versement à l'inventaire général du Ministère de la Culture, classement de 22 instruments au titre des Monuments Historiques, inventaire et numérisation des archives anciennes, montage d'expositions et réalisation du catalogue Telescopium, 400 ans de lunettes et de télescopes. Nous présenterons les actions en cours: mesures de conservation préventive, inventaire des archives et des instruments. Nous parlerons enfin des projets: création d'un espace d'exposition permanente, participation à des expositions temporaires.

Continuous Dependence on Modeling in the Cauchy Problem for Nonlinear Elliptic Equations.

DTIC Science & Technology

1987-04-01

problema di Cauchy per le equazione di tipo ellitico, Ann. Mat. Pura Appl., 46 (1958), pp. 131-153 [18] P. W. Schaefer, On the Cauchy problem for an...Continued) PP 438 PP 448 Fletcher, Jean W. Supply Problems in the Naval Reserve, Cymrot, Donald J., Military Retiremnt and Social Security: A 14 pp

Three-dimensional modeling of n+-nu-n+ and p+-pi-p+ semiconducting devices for analog ULSI microelectronics

NASA Astrophysics Data System (ADS)

Gillet, Jean-Numa; Degorce, Jean-Yves; Belisle, Jonathan; Meunier, Michel

2004-03-01

Three-dimensional modeling of n^+-ν -n^+ and p^+-π -p^+ semiconducting devices for analog ULSI microelectronics Jean-Numa Gillet,^a,b Jean-Yves Degorce,^a Jonathan Bélisle^a and Michel Meunier.^a,c ^a École Polytechnique de Montréal, Dept. of Engineering Physics, CP 6079, Succ. Centre-vile, Montréal, Québec H3C 3A7, Canada. ^b Corresponding author. Email: Jean-Numa.Gillet@polymtl.ca ^c Also with LTRIM Technologies, 140-440, boul. A.-Frappier, Laval, Québec H7V 4B4, Canada. We present for the first time three-dimensional (3-D) modeling of n^+-ν -n^+ and p^+-π -p^+ semiconducting resistors, which are fabricated by laser-induced doping in a gateless MOSFET and present significant applications for analog ULSI microelectronics. Our modeling software is made up of three steps. The two first concerns modeling of a new laser-trimming fabrication process. With the molten-silicon temperature distribution obtained from the first, we compute in the second the 3-D dopant distribution, which creates the electrical link through the device gap. In this paper the emphasis is on the third step, which concerns 3-D modeling of the resistor electronic behavior with a new tube multiplexing algorithm (TMA). The device current-voltage (I-V) curve is usually obtained by solving three coupled partial differential equations with a finite-element method. A 3-D device as our resistor cannot be modeled with this classical method owing to its prohibitive computational cost in three dimensions. This problem is however avoided by our TMA, which divides the 3-D device into one-dimensional (1-D) multiplexed tubes. In our TMA 1-D systems of three ordinary differential equations are solved to determine the 3-D device I-V curve, which substantially increases computation speed compared with the classical method. Numerical results show a good agreement with experiments.

Le contrôle des infections au cabinet du pédiatre

PubMed Central

2008-01-01

RÉSUMÉ La transmission des infections au cabinet du pédiatre est de plus en plus préoccupante. Le présent document expose les voies de transmission des infections et les principes sous-jacents aux mesures actuelles pour contrôler les infections. Pour prévenir les infections, il faut bien concevoir le cabinet et adopter des politiques administratives et de triage convenables, de même que des pratiques de base pour les soins de tous les patients (p. ex., hygiène des mains, port de gants, de masques, de lunettes de protection et d’une blouse d’hôpital pour des interventions précises; nettoyage, désinfection et stérilisation convenables des surfaces et du matériel, y compris les jouets, et techniques d’asepsie en cas d’interventions effractives) et des précautions additionnelles en cas d’infections précises. Le personnel doit avoir reçu les vaccins pertinents, et les personnes infectées doivent respecter les politiques de restriction au travail.

Transitions de phase dans le oxyde de yttrium vanadium

NASA Astrophysics Data System (ADS)

Roberge, Benoit

Dans le mémoire qui suit, les ordres structural, magnétiques et orbital dans le YVO3 sont étudiés avec l'aide de la diffraction des rayons X,de la spectroscopie Raman et de la technique de la cavité résonnante hyperfréquence. L'objectif premier consiste à observer l'évolution de ces ordres en fonction de la température. Le mémoire met ensuite en évidence le couplage entre les différents ordres cohabitants dans le YVO3 . Les mesures effectuées par la diffraction des rayons X permettent de mesurer le caractère polycrystallin des échantillons du YVO 3. Une comparaison de nos mesures avec des mesures de diffraction des rayons X faites sur la poudre de YVO3 indique la faible présence de maclage. Les mesures effectuées avec la technique de résonnance hyperfréquence permettent de suivre l'évolution de la constante diélectrique en fonction de la température. Les changements impliquant l'ordre orbital se manifestent de manière évidente dans la constante diélectrique à 200 K et à 77 K. La transition diélectrique détectée à 77 K est une transition de premier ordre. Un couplage entre les propriétés diélectriques et magnétiques est observable à la température de Néel à 114 K. L'effet d'un champ magnétique fixe sur la température de transition de l'ordre orbital survenant à 77 K est également remarquable. Cela indique un couplage magnétodiélectrique démontrant ainsi le caractère multiferroïque du YVO 3. Finalement, l'observation d'un mécanisme de relaxation pouvant être modélisé par le modèle d'Havriliak-Negami est observé en dessous de 77 K. En utilisant le modèle d'Arrhénius et le modèle d'Havriliak-Negami, on peut caractériser le mécanisme avec son énergie d'activation et son temps de relaxation. Les mesures effectuées en spectroscopie Raman permettent de suivre l'évolution de la structure du YVO3 en fonction de la température. Les deux changements structuraux survenant à 200 K et 77 K sont observés. Le

Sparking controversy: Jean Antoine Nollet and medical electricity south of the Alps.

PubMed

Bertucci, Paola

2005-01-01

The paper considers a significant episode in the history of eighteenth-century electricity: the controversy over the "medicated tubes". Invented by the Italian erudite Gianfrancesco Pivati, the tubes were said to produce instantaneous cures. Jean Antoine Nollet was one of the main actors of the controversy. In 1749, after touring Italy to see for himself the Italian tubes and their effects, he published a report, discrediting Pivati's accounts. This study shows that the report, which has since been the main source for interpretations of the controversy, hides the key role of the Bologna Istituto delle Scienze in promoting Pivati's invention. Relying on manuscript sources, I propose a change of perspective on the controversy that illuminates the world of Italian experimental philosophy during the Enlightenment and its place in the Republic of Letters. I also analyze the reasons for Nollet's silence over the involvement of the Istituto delle Scienze in the controversy and the relevance of medical electricity in the wider context of contemporary electrical experimental philosophy.

Profil anatomopathologique du cancer du sein dans le cap bon tunisien

PubMed Central

Sahraoui, Ghada; Khanchel, Fatma; Chelbi, Emna

2017-01-01

Le cancer du sein est le cancer le plus fréquent de la femme en Tunisie et dans le monde. Dans le Cap Bon tunisien, les particularités anatomopathologiques de ce cancer n'ont pas été précisées auparavant. Leur connaissance est nécessaire pour l'adaptation des systèmes de prévention et de soins dans la région. Le but de notre étude était de déterminer le profil anatomopathologique des carcinomes mammaires dans l'unique laboratoire d'anatomie pathologique publique de la région. Il s'agissait d'une étude descriptive rétrospective des carcinomes mammaires diagnostiqués chez 116 malades dans notre laboratoire sur une période de 5 ans de Juillet 2010 à Juillet 2015. Notre étude a inclus 116 patientes. L'âge moyen était de 51 ans. La taille tumorale histologique moyenne était de 31 mm. Le diagnostic initial était posé sur pièce de tumorectomie dans 83% des cas. Le carcinome infiltrant de type non spécifique était le type histologique le plus fréquent. Le grade SBR III était majoritaire. L'invasion lympho-vasculaire était présente dans 33% des cas. Le curage axillaire était positif dans 72% des cas. Les récepteurs hormonaux étaient positifs dans 73% des cas. Les récepteurs de l'Her2-Neu étaient surexprimés dans 19% des cas. Le ki67 était ≥ 14% dans 38%. Le sous-type moléculaire le plus fréquent était le luminal A. Le carcinome mammaire dans la région du Cap Bon se caractérise par sa survenue à un âge jeune, son importante taille tumorale et la fréquence de facteurs histopronostiques péjoratifs. PMID:28450990

Le pôle de métrologie de SOLEIL

NASA Astrophysics Data System (ADS)

Idir, M.; Brochet, S.; Delmotte, A.; Lagarde, B.; Mercere, P.; Moreno, T.; Polack, F.; Thomasset, M.

2006-12-01

Le Pôle de METROLOGIE de SOLEIL a pour objet de créer sur le synchrotron SOLEIL, une plateforme constituée : - une ligne de lumière utilisant le rayonnement synchrotron (métrologie dite à la longueur d'onde) - d'un laboratoire de métrologie associé (métrologie dite ll classique gg ) Ces deux types de Métrologie sont l'une et l'autre indispensables pour soutenir l'activité de recherche instrumentale en optique X et X-UV. Ce projet de pôle de METROLOGIE ne répondra pas seulement aux besoins des groupes chargés de l'équipement du synchrotron SOLEIL en optiques et détecteurs mais aussi pour préparer, tester et mettre au point les postes expérimentaux, ce qui concerne déjà une large communauté d'utilisateurs. Il sera aussi largement ouvert, dès sa mise en service, à l'ensemble de la communauté scientifique concernée par l'instrumentation X et XUV en Ile de France, en France, voire même en Europe si la demande continue de croître plus vite que l'offre dans ce domaine. Ligne de lumière Métrologie à la longueur d'onde La ligne de lumière sera équipée de plusieurs stations permettant de mesurer, dans la plus grande partie du spectre couvert par le synchrotron, les paramètres photométriques qui caractérisent les éléments optiques, tels que : la réflectivité de surfaces, l'efficacité de diffraction des réseaux, la diffusion des surfaces ou l'efficacité des détecteurs X et X-UV et la calibration absolue. Cette installation pourra servir également à développer des instruments et des diagnostics nécessaires à la caractérisation des faisceaux de rayons X (intensité, taille, degré de cohérence, polarisation etc.) Métrologie Classique La métrologie des surfaces optiques est devenue une nécessité critique pour les laboratoires et les industries qui utilisent les photons X et X-UV (synchrotrons, centres laser, etc. .). En effet, les progrès de calcul et de conception des systèmes optiques pour ces longueurs d'onde (optiques

[Baron Dominique-Jean Larrey: the founder of urological traumatology].

PubMed

Hatzinger, M; Ameijenda, C; Lent, V; Sohn, M

2012-12-01

Dominique-Jean Larrey (1766-1842) was Surgeon-in-Chief of the Grande Army under Napoleon Bonaparte (1769-1821) and personal physician of the Emperor. Against the opposition of the traditionalists he introduced the "ambulances volantes", the so-called flying ambulances. The aim was the medical treatment of the injured soldiers immediately on the battlefield. This revolutionary treatment led to a benefit not only for the own soldiers, but also for the wounded enemies. His innovation in the field of immediate assistance of wounded persons, together with Larreys' outstanding medical competence, saved thousands of soldiers lives on the battlefield of the Napoleonic wars. His memories concerning the military campaigns, have been even up to the 20th century one of the standard works of modern military surgery. He had as well great interest in urolological injuries of the urinary system and their conservative and operative care. Up to these days, his work shows a surprising actuality and perfect anatomic understanding. In a time without anaesthetics, antibiotics and under primitive circumstances, Larrey and his collegues accomplished surgical feats. Larreys flying ambulances were copied by many different countries. The American Mobile Army Surgical Hospital (M.A.S.H) is clearly based on his thoughts and ideals. In our opinion he is the father of the modern war surgery as well the urological traumatology. Georg Thieme Verlag KG Stuttgart · New York.

Jean-Jacques Rousseau's copy of Albrecht von Haller's Historia stirpium indigenarum Helvetiae inchoata (1768).

PubMed

Cook, A

2003-04-01

Jean-Jacques Rousseau sold his botanical texts to Daniel Malthus (father of Thomas Malthus) about 1775. Two of these are now in the Old Library, Jesus College, Cambridge, but all the rest have long been thought lost. However, a copy of Albrecht von Haller's Historia stirpium indigenarum Helvetiae inchoata (1768) in the Lindley Library, Royal Horticultural Society, London, bears Rousseau's name and seems to have been annotated by him. The volume contains the bookplate of Jane Dalton, a cousin to whom Malthus willed "all[his] Botanical Books in which the name of Rousseau is written". Haller was well-known to Rousseau, who while in exile in the Swiss Jura (1763-1765), studied under one of Haller's collaborators, Abraham Gagnebin. Rousseau cited Haller's entry 762 when describing a species of Seseli to the Duchess of Portland.

LA SAFE and Isle de Jean Charles: Regional Adaptation and Community Resettlement Planning

NASA Astrophysics Data System (ADS)

Sanders, M.

2017-12-01

LA SAFE, or Louisiana's Strategic Adaptations for Future Environments, is a strategic framework for community development utilizing future projections of coastal land loss and flood risk as a determining factor in regional growth management and local planning initiatives along a 10, 25, and 50 year timeline. LA SAFE utilizes the input of passionate local citizen leaders and organizations committed to enabling community members to take proactive steps towards mitigating risk and increasing resilience against coastal issues. The project aims to acknowledge that adaptation and restoration must go hand-in-hand with addressing community growth and contraction, as well as realizing Louisiana's most vulnerable coastal communities will need to contemplate resettlement over the next 50 years. The project's outlook is to become a global leader for adaptation and cultural design and restoration. Connecting a global interest with the project and offering extensive ways for people to learn about the issues and get involved will provide an immense amount of support necessary for future coastal environments around the world. This presentation will focus on the output of a year-long planning effort across a six-parish target area encompassing several vulnerable coastal Louisiana locales. The Resettlement of Isle de Jean Charles is a federally-funded and first-of-its kind initiative marking Louisiana's first attempt to relocate a vulnerable coastal community at-scale and as a group. Due to a myriad of environmental factors, the Island has experienced 98 percent land loss since 1955, leading to many of the Island's historical inhabitants to retreat to higher, drier landscapes. In moving the community at-scale, the project seeks to inject new life into the community and its residents in relocating the community to higher, safer ground, while also developing the new community in such a way that it maximizes economic development, job training, and educational opportunities and can be a

Environmental Assessment: Reevaluation of the Le Claire Base Construction Storage Yard, Le Claire, Iowa

DTIC Science & Technology

1988-06-01

RUYWAT~POF TU LZ CM AU1 CCRSTCTION STOIAGE YARD TS OF CONENT 3. Pupobe wA X 4 for Action EA- I 11. Project DescriptioO EA- 2 III. Alternatives EA- 4 IV...r W - - 3ENVIRONMENTAL ASSESSMENT REEVALUATION OF THE LE CLAIRE BASE CONSTRUCTION STORAGE YARD LE CLAIRE, IOWA I . PURPOSE AND NEED FOR...IDNR) boat ramp and the Corps storage yard will be relocated to the downstream (western) end of the new storage yard (see plate I ). The new road

Facteurs de risque de l'infection par le VIH dans le district de santé de Meyomessala au Cameroun

PubMed Central

Mbopi-Keou, Francois-Xavier; Nguefack-Tsague, Georges; Kalla, Ginette Claude Mireille; Abessolo, Stéphanie Abo'o; Angwafo, Fru; Muna, Walinjom

2014-01-01

Introduction L'objectif de ce travail était de déterminer les facteurs de risque de l'infection par le VIH dans le district de santé de Meyomessala (Région du Sud) au Cameroun. Méthodes Il s'agissait d'une étude transversale, descriptive et analytique qui s'est déroulée de Février à Mai 2011. Pour cette étude, nous avons obtenu une clairance éthique. Résultats L’échantillon était constitué de 315 participants dont 181 (57,46%) hommes et 134 (42,54%) femmes. L’âge moyen était de 24,5±8ans (extrême: 15-45ans). Quarante personnes (40) étaient séropositifs, soit une prévalence de l'infection par le VIH de 12,7%. Cette prévalence augmentait significativement (p = 0) avec le nombre de partenaires occasionnels au cours des douze derniers mois, allant de 2,7% chez ceux n'ayant eu aucun partenaire occasionnel à 21,25% chez ceux ayant plus de trois partenaires occasionnels (RC = 9,72; IC = 1,27-74,14; P = 0,03). le fait d’être âgé entre 20 et 24 ans (RC = 4,88; IC = 1,74-13,67; p = 0), avoir plus de trois partenaires sexuels au cours des douze derniers mois (RC = 9,72; IC = 1,27-74,14; p = 0,03), avoir les rapports sexuels avec les prostitués (RC = 2,86; IC = 1,42-5,76; p = 0), avoir eu le chlamydia (RC = 3,00; IC = 1,07-8,39; p = 0,04), avoir eu la syphilis (RC = 3,35; IC = 1,57-7,14; p = 0), avoir des avantages sociaux lors du premier rapport sexuel (RC = 2,57; IC = 1,03-6,43; p = 0,04) constituaient des potentiels facteurs de risque du VIH. Conclusion Il apparait urgent d'intensifier les campagnes de sensibilisation au risque d'infection par le VIH et les maladies sexuellement transmissibles dans le district de santé de Meyomessala PMID:25419299

LeMAPK1, LeMAPK2, and LeMAPK3 are associated with nitric oxide-induced defense response against Botrytis cinerea in the Lycopersicon esculentum fruit.

PubMed

Zheng, Yanyan; Hong, Hui; Chen, Lin; Li, Jingyuan; Sheng, Jiping; Shen, Lin

2014-02-12

Nitric oxide (NO) and mitogen-activated protein kinases (MAPKs) are signal molecules involved in the disease resistance of plants. To investigate the role of tomato MAPKs in the NO-mediated defense response, mature green tomatoes (Lycopersicon esculentum Mill. cv. Qian-xi) were treated with a MAPKs inhibitor (1,4-diamino-2,3-dicyano-1,4-bis(o-amino-phenylmercapto) butadiene (U0126)), NO donor sodium nitroprusside (SNP), and SNP plus U0126. Treatment with U0126 increased the incidence of disease and size of lesion areas in the tomato fruits after being inoculated with Botrytis cinerea. NO enhanced the resistance of the tomato fruits against Botrytis cinerea invasion and the activities of nitric oxide synthase, Chitinase, β-1,3-glucanase, polyphenol oxidase, and phenylalanine ammonia-lyase. However, the effects of NO on disease resistance were weakened by the MAPKs inhibitor. Meanwhile, the relative expression of LeMAPK1, LeMAPK2, and LeMAPK3 in the (SNP + U0126)-treated fruits was lower than that in the SNP-treated fruits. The results suggest that LeMAPK1/2/3 are involved in NO-induced disease resistance of tomato fruits against Botrytis cinerea.

Searching the animal psyche with Charles Le Brun.

PubMed

Cohen, Sarah R

2010-07-01

Around 1670 the French court painter and Academician Charles Le Brun produced a series of drawings featuring naturalistic animal heads, as well as imaginary heads in which he refashioned various nonhuman animal species to make humanoid physiognomies. What were the purpose and significance of these unusual works? I argue that they show Le Brun's interest in what we today would call animal psychology: focusing upon the sensory organs and their connections with the animal's brain, Le Brun studied his animals as conscious protagonists of the natural realm. One source that may have served him in this project was Marin Cureau de La Chambre's De la Connoissance des bestes of 1645, in which the physician argued that animals possess a conscious soul grounded in the senses. However, Le Brun's animal-humans have no clear place in the artist's taxonomy--nor, indeed, in any seventeenth-century understandings of species. It is rather John Locke, at his most skeptical, who offers the best parallel in the realm of natural philosophy to Le Brun's unsettling animal-humans. Probably without meaning to, Le Brun demonstrated through his eerie, boundary-crossing creatures the limits of visual classification.

Le Chatelier's principle in replicator dynamics

NASA Astrophysics Data System (ADS)

Allahverdyan, Armen E.; Galstyan, Aram

2011-10-01

The Le Chatelier principle states that physical equilibria are not only stable, but they also resist external perturbations via short-time negative-feedback mechanisms: a perturbation induces processes tending to diminish its results. The principle has deep roots, e.g., in thermodynamics it is closely related to the second law and the positivity of the entropy production. Here we study the applicability of the Le Chatelier principle to evolutionary game theory, i.e., to perturbations of a Nash equilibrium within the replicator dynamics. We show that the principle can be reformulated as a majorization relation. This defines a stability notion that generalizes the concept of evolutionary stability. We determine criteria for a Nash equilibrium to satisfy the Le Chatelier principle and relate them to mutualistic interactions (game-theoretical anticoordination) showing in which sense mutualistic replicators can be more stable than (say) competing ones. There are globally stable Nash equilibria, where the Le Chatelier principle is violated even locally: in contrast to the thermodynamic equilibrium a Nash equilibrium can amplify small perturbations, though both types of equilibria satisfy the detailed balance condition.

Le Chatelier's principle in replicator dynamics.

PubMed

Allahverdyan, Armen E; Galstyan, Aram

2011-10-01

The Le Chatelier principle states that physical equilibria are not only stable, but they also resist external perturbations via short-time negative-feedback mechanisms: a perturbation induces processes tending to diminish its results. The principle has deep roots, e.g., in thermodynamics it is closely related to the second law and the positivity of the entropy production. Here we study the applicability of the Le Chatelier principle to evolutionary game theory, i.e., to perturbations of a Nash equilibrium within the replicator dynamics. We show that the principle can be reformulated as a majorization relation. This defines a stability notion that generalizes the concept of evolutionary stability. We determine criteria for a Nash equilibrium to satisfy the Le Chatelier principle and relate them to mutualistic interactions (game-theoretical anticoordination) showing in which sense mutualistic replicators can be more stable than (say) competing ones. There are globally stable Nash equilibria, where the Le Chatelier principle is violated even locally: in contrast to the thermodynamic equilibrium a Nash equilibrium can amplify small perturbations, though both types of equilibria satisfy the detailed balance condition.

Le syndrome d'embolie graisseuse post traumatique

PubMed Central

Berdai, Adnane Mohamed; Shimi, Abdelkarim; Khatouf, Mohammed

2014-01-01

Le syndrome d'embolie graisseuse est une complication grave des fractures des os longs, il est la conséquence de la dissémination des particules graisseuses dans la microcirculation. L'objectif de ce travail est de déterminer le profil épidémiologique, la présentation clinique et paraclinique de ce syndrome et sa prise en charge thérapeutique. Notre étude porte sur 11 cas de syndrome d'embolie graisseuse colligés au service de réanimation A1 au centre hospitalier universitaire Hassan II de Fès, de Janvier 2009 à Juin 2012. Le diagnostic positif est basé sur les critères de Gurd. Les cas collectés se caractérisent par la prédominance du sexe masculin, d'un âge inférieur à 40 ans, présentant une fracture fémorale. Ce syndrome survient souvent dans les 72 heures après le traumatisme. La présentation clinique est dominée par l'hypoxémie et les troubles de conscience. Sur le plan biologique: l'anémie et la thrombopénie sont les manifestations les plus fréquentes. La prise en charge est symptomatique, 63% des patients ont nécessité l'intubation et la ventilation. L’évolution n'est pas toujours bénigne. Nos résultats confirme le polymorphisme de la présentation clinique et paraclinique du syndrome d'embolie graisseuse. Le diagnostic de ce syndrome se base sur des critères cliniques, mais reste essentiellement un diagnostic d’élimination. La prise en charge est symptomatique. La prévention de ce syndrome est essentielle et se base sur une fixation précoce des fractures des os longs. PMID:25452829

Le consentement libre et éclairé aux soins en psychiatrie

PubMed Central

Neilson, Grainne; Chaimowitz, Gary

2015-01-01

Résumé Le patient a le droit d’être informé sur les soins de santé qui lui sont proposés et de participer activement à la prise de décisions relativement à ces soins. Le respect de la dignité et de l’autonomie de la personne passe par le respect de son droit de prendre des décisions à propos de ses soins psychiatriques, notamment de refuser un traitement, pour autant qu’elle soit apte à prendre des décisions. Il importe que le psychiatre connaisse les fondements éthiques du consentement libre et éclairé et les exigences prévues par le droit en cette matière, y compris la jurisprudence. Le consentement n’est pas immuable, pouvant changer avec le temps, au fil de l’évolution des conditions et des circonstances. Par conséquent, le consentement doit être un processus continu.

In memoriam: Jean Blancou, DVM, 1936-2010. World authority on rabies, historian and former Director General of the World Organisation for Animal Health (Office International des Épizooties: OIE).

PubMed

2011-01-01

Jean-Marie Blancou was born in Bangui on 28 August 1936 and passed away in Paris on 10 November 2010 at the age of 74. After studying at the Pierre de Fermat Lycée in Toulouse, Jean Blancou graduated from the Toulouse Veterinary School in 1960. He continued his studies in tropical veterinary medicine in Paris until 1963, extending his knowledge of immunology, microbiology, biochemistry and zoology, at the Institut Pasteur. He obtained his doctorate in biological sciences at the University of Nancy in 1982. Jean Blancou commenced his career as technical adviser to the Veterinary Services of Ethiopia where he directed a campaign against rinderpest in the south of the county. From 1965 to 1967 he was deputy director of the national veterinary laboratory in Niamey where he was responsible for the diagnosis of animal diseases and the production of veterinary vaccines. In 1967, he moved to the central livestock laboratory in Madagascar, where he commenced research on the diagnosis and control of dermatophilosis, bovine tuberculosis and other bacterial and parasitic diseases. In August 1968 he married Geneviève Orue. In 1975 he was appointed as head of the national veterinary laboratory in Senegal, where he remained until 1977. Initially deputy director, and then director of Research on rabies and wildlife diseases, at the World Health Organization collaborating centre in Nancy, he remained in this position until 1990. Jean Blancou was recognised as a world authority on rabies. He conducted research into the diagnosis, aetiology, epidemiology and control of rabies during his time in Nancy. Between 1988 and 1990, Dr Blancou also headed the animal health and protection department of the Centre national d'études vétérinaires et animales (CNEVA) in Maisons-Alfort. On 1 January 1991, he was appointed director general of the World Organisation for Animal Health (Office International des Épizooties: OIE) and was re-elected in 1995 for a further five-year term, until he

Jean-Louis Brachet (1789-1858). A forgotten contributor to early 19th century neurology.

PubMed

Walusinski, O

2015-10-01

Specialists of the history of hysteria know the name of Jean-Louis Brachet (1789-1858), but few realise the influence of this physician and surgeon from Lyon, a city in the southeastern part of France. Not only a clinician, he was also a neurophysiology researcher in the early 19th century. Along with his descriptions of meningoencephalitis, including hydrocephalus and meningoencephalitis, he elucidated the functioning of the vegetative nervous system and described its activity during emotional states. He also helped describe the different forms of epilepsy and sought to understand their aetiologies, working at the same time as the better-known Louis-Florentin Calmeil (1798-1895). We present a biography of this forgotten physician, a prolific writer, keen clinical observer and staunch devotee of a rigorous scientific approach. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

Jean-Anthelme Brillat-Savarin's 1825 treatise on the mouth and ingestion.

PubMed

Chong, Gabriel Tse Feng

2012-12-01

This article quotes and discusses Jean-Anthelme Brillat-Savarin's musings on the mouth and ingestion as described in his book The Physiology of Taste. The book was first published in France in December 1825, and is still widely read as a key work in Gastronomy today. The mouth is intimately related to the acts of chewing, swallowing and eating and it would be interesting to report an early 19th century epicurean's views on the mouth. Passages from Brillat-Savarin's book describing the functions of the teeth and tongue and the acts of tasting, chewing, and swallowing are quoted in full. Anecdotes also include one on the horrifying punishment of having one's tongue removed and another illustrating the poor oral health found among Europeans of that era. His work offers a unique glimpse into how a 19th century gastronome viewed the oral cavity and its gastronomical functions. While some of his writings may appear archaic and antediluvian to the modern reader; others relating to, for example chewing and swallowing, are surprisingly accurate by contemporary standards. Nonetheless, the gastronomic savant seemed to know a lot right about modern stomatology! Copyright © 2012. Published by Elsevier B.V.

"To afford the wounded speedy assistance": Dominique Jean Larrey and Napoleon.

PubMed

Skandalakis, Panagiotis N; Lainas, Panagiotis; Zoras, Odyseas; Skandalakis, John E; Mirilas, Petros

2006-08-01

Dominique Jean Larrey (1766-1842) has been described as the father of modern military surgery and is considered even today as the model military surgeon. He developed a plan of rapid evacuation of wounded soldiers from the battlefield during combat, using flexible medical units which he named ambulances volantes ("flying ambulances"). He won the admiration of Napoleon Bonaparte (1769-1821), who was amazed by the results of Larrey's sanitary system. Larrey spent almost 18 years with Napoleon, accompanying him in 25 campaigns, 60 battles, and more than 400 engagements. Napoleon's enormous military success was due not only to his strategy and skill but also to the medical services provided by Larrey. The surgeon became a master of wound management and limb amputation. In his vivid battlefield journals, Larrey documented the course of tetanus, the pathophysiology of cold injury, the effective control of hemorrhage, the drainage of empyema and hemothorax, the aspiration of pericardial effusion or hemopericardium, and the packing of sucking chest wounds. Larrey established a categorical rule for the triage of war casualties, treating the wounded according to the observed gravity of their injuries and the urgency for medical care, regardless of their rank or nationality.

Effets du stress familial lié au diabète sur le contrôle glycémique chez les jeunes diabétiques de type 1

PubMed Central

Tsiouli, Elina; Alexopoulos, Evangelos C.; Stefanaki, Charikleia; Darviri, Christina; Chrousos, George P.

2013-01-01

Objectif Examiner la façon dont le stress familial influence le contrôle glycémique chez les patients diabétiques de moins de 18 ans. Sources des données Une recherche des études pertinentes publiées depuis 1990 a été réalisée dans PubMed et Scopus à l'aide des mots-clés suivants en anglais: diabetes type 1, glycemic control, family stress, family conflict et family function. Sélection des études La recension initiale a permis de cerner un total de 1 478 articles. La synthèse finale portrait sur 6 études de cohortes, 3 études transversales et 1 étude qualitative dans lesquelles le stress familial était évalué à l'aide d'instruments de mesure des conflits spécifiquement reliés au diabète et le contrôle glycémique était mesuré en fonction de l'hémoglobine glycosylée. Synthèse Dans la plupart des études, il existait une corrélation négative entre le stress familial et le contrôle glycémique des patients. Le bon fonctionnement familial était fortement relié à un bon contrôle glycémique des patients, tandis que les conflits familiaux étaient associés à un mauvais contrôle glycémique. Les familles dont la situation socioéconomique était défavorisée, celles ayant des adolescents atteints de diabète et les familles monoparentales étaient plus enclines à vivre un stress relié au diabète et étaient, par conséquent, plus susceptibles de connaître un moins bon contrôle glycémique. Conclusion Les interventions psychologiques thérapeutiques et les programmes éducatifs peuvent aider à atténuer le stress familial relié au diabète et amélioreront probablement le contrôle glycémique.

Agression sexuelle et violence dans les relations amoureuses : Le rôle médiateur du stress post-traumatique

PubMed Central

Hébert, Martine; Daspe, Marie-Ève; Blais, Martin; Lavoie, Francine; Guerrier, Mireille

2017-01-01

Résumé Cette étude vise à documenter le rôle médiateur des symptômes de stress post-traumatique (SSPT) dans le lien entre l’agression sexuelle et différentes formes de victimisation vécues dans le contexte de relations amoureuses. L’étude se fonde sur l’Enquête sur les parcours amoureux des jeunes (PAJ), réalisée au sein de 34 écoles secondaires du Québec. Les jeunes ont rempli un questionnaire portant sur leurs expériences de victimisation, y compris l’agression sexuelle vécue pendant l’enfance et la violence psychologique, physique et sexuelle vécue au sein de leurs relations amoureuses dans les 12 derniers mois. Les SSPT ont été évalués à l’aide du UCLA PTSD Index. Sur un total de 8 194 adolescents, 15% des filles et 4% des garçons ont rapporté avoir vécu une agression sexuelle. Les résultats des analyses acheminatoires semblent indiquer que le fait d’avoir été victime d’agression sexuelle est associé à davantage de SSPT et qu’en retour, les SSPT sont positivement associés à la violence psychologique, physique et sexuelle subie de la part d’un partenaire amoureux. Cette étude comporte des implications pratiques pour la prévention et l’intervention sur le plan de la violence dans les relations amoureuses chez les victimes d’agression sexuelle. PMID:29321695

Quatrième conférence consensuelle sur le diagnostic et le traitement de la démence

PubMed Central

Moore, Ainsley; Patterson, Christopher; Lee, Linda; Vedel, Isabelle; Bergman, Howard

2014-01-01

Résumé Objectif Revoir les stratégies diagnostiques de la maladie d’Alzheimer, actualiser les recommandations concernant le traitement des symptômes de démence et proposer une approche thérapeutique à la démence d’apparition précoce et d’évolution rapide. Composition du comité Des spécialistes et des délégués de diverses régions du Canada et représentant diverses disciplines pertinentes ont discuté et se sont mis d’accord sur les révisions à apporter aux lignes directrices de 2006. Méthodologie On a eu recours au système GRADE (grading of recommendations, assessment, development, and evaluation) pour évaluer le consensus concernant les recommandations, lequel était défini comme suit : lorsque 80 % ou plus des participants ont voté en faveur de la recommandation. La cote des données probantes est rapportée lorsque cela est possible. Rapport important pour les médecins de famille, malgré les progrès effectués dans les domaines des biomarqueurs liquidiens et de la neuro-imagerie, le diagnostic de démence au Canada demeure fondamentalement clinique. De nouveaux critères cliniques essentiels de diagnostic de la maladie d’Alzheimer en reconnaissent dorénavant les formes moins fréquentes et non amnestiques. La démence précoce, une affection rare, mais importante, devrait inciter les médecins à aiguiller les patients vers un spécialiste ayant accès à des conseillers en génétique. La démence d’évolution rapide, mal définie dans la littérature, faciliterait le dépistage de cette affection rare, mais importante. Les inhibiteurs de la cholinestérase sont maintenant indiqués pour le traitement d’affections autres que la maladie d’Alzheimer. Des lignes directrices concernant l’arrêt du traitement, lesquelles n’existaient pas auparavant, sont également apparues. De nouvelles données probantes sur le recours à la mémantine, aux antidépresseurs et à d’autres agents psychotropes dans le traitement de la

The Hawthorne experiments and the introduction of Jean Piaget in American industrial psychology, 1929-1932.

PubMed

Hsueh, Yeh

2002-05-01

The Hawthorne interview program between 1929 and 1932 was one of the most significant industrial studies in the United States. The Hawthorne researchers applied Jean Piaget's clinical method in their extensive interviews with tens of thousands of workers. Chiefly responsible for the program's methodology was Elton Mayo, an Australian who saw interviewing as a means to promote social cooperation. Previous discussions of the Hawthorne experiments have ignored the influence of Piaget in the social sciences. This article provides an account of Mayo's and the Hawthorne researchers' efforts to fuse Piaget's innovation with burgeoning American industrial psychology. The endeavor was not an isolated event but rather drew on the theories and practice of Janet-Piaget psychology, on the support of the Laura Spelman Rockefeller Memorial Foundation, and on the discourse among social scientists about Piaget's work.

New data on Jean-Étienne Guettard's journey to Poland in the years 1760-1762

NASA Astrophysics Data System (ADS)

Tarkowski, Radosław

2004-10-01

This paper presents new information on the journey of the French geologist Jean-Étienne Guettard to Poland in the years 1760-1762. Search in the Archives of the Academy of Sciences in Paris, especially a review of his biographic dossier and collections of documents reports delivered at the meetings of the Academy, made it possible to find rich material (letters, reports, notes from field studies, drafts of lectures and others), a large part of which refers to this journey. This hitherto overlooked material well supplements our knowledge of the journey and casts some new light on the scope and extent and results of geological and meteorological studies carried out by J.-É. Guettard during his stay in Poland. To cite this article: R. Tarkowski, C. R. Geoscience 336 (2004).

Le surpoids, l’obésité et le contrôle glycémique chez les diabétiques du centre de référence provincial de diabète (CRD), Kénitra, Maroc

PubMed Central

Lotfi, Zeghari; Aboussaleh, Youssef; Sbaibi, Rachid; Achouri, Imane; Benguedour, Rachid

2017-01-01

Introduction Le diabète est définit comme un trouble de l'assimilation, de l'utilisation et du stockage des sucres apportés par l'alimentation, sa prise en charge est assurée par le suivi du surpoids et l'obésité et le contrôle glycémique régulier. L'objectif de ce travail était l'étude du surpoids, l'obésité et le contrôle glycémique chez 2227 diabétiques de différent type (type 1, 2 et gestationnel), consultants le centre de référence provincial de diabète (CRD), Kénitra-Maroc. Méthodes L'étude s'est déroulée sur une période d'une année du mois janvier au mois décembre 2015, L'évaluation du surpoids et l'obésité a été effectuée par le calcul de l'Indice de Masse Corporelle (IMC=Poids/Taille2 (Kg/m2)), elles sont définit respectivement par IMC > 25 Kg/m2, et IMC > 30 Kg/m2, le poids et la taille ont été mesurés selon les recommandations de l'organisation mondiale de santé (OMS), Le contrôle glycémique a été effectué par l'analyse sanguine de l'Hémoglobine glycosylée et de la Glycémie à jeun. Les normes sont 7% pour l'Hémoglobine glycosylée et 0,70g/l à 1,10g/l pour la Glycémie à jeun. Résultats L'intervalle d'âges des patients est compris entre 8 mois et 80 ans, avec une dominance des diabétiques provenant du milieu urbain (74%) par rapport à ceux provenant du milieu rural (26%). Le surpoids touche l'ensemble de cette population. L'IMC moyen des femmes tends vers l'obésité (IMC≈30): (29,21 Kg/m2 ± 3,1) pour le diabète gestationnel et (29,15 Kg/m2 ± 3,2) pour le diabète de type 2. Les valeurs du contrôle glycémique sont supérieures aux normes: avec 8,5% ± 2,6 > 7% pour l'hémoglobine glycosylée et 1,5 g/l ± 1,3 > 1,10g/l pour la Glycémie à jeun. La différence entre les valeurs de l'hémoglobine glycosylée entre les hommes (8,5 7% ± 2,6) et les femmes (8,1% ± 2,3) n'est pas significative (P > 0,05), même chose pour la Glycémie capillaire à jeun: pour les hommes (1,44 g/l ± 1,1) et les

Le genre Tunga Jarocki, 1838 (Siphonaptera : Tungidae). I – Taxonomie, phylogénie, écologie, rôle pathogène

PubMed Central

Beaucournu, J.-C.; Degeilh, B.; Mergey, T.; Muñoz-Leal, S.; González-Acuña, D.

2012-01-01

Pour la première fois, les 12 espèces actuellement décrites dans le genre Tunga sont étudiées sur le plan de la taxonomie et de la répartition. Divers aspects de leur biologie et leur rôle pathogène sont également envisagés, et en particulier leur phylogénie, leur chorologie, leur phénologie, leur sexe-ratio et leurs dermecos. PMID:23193514

Infiltration into soils: Conceptual approaches and solutions

NASA Astrophysics Data System (ADS)

Assouline, Shmuel

2013-04-01

Infiltration is a key process in aspects of hydrology, agricultural and civil engineering, irrigation design, and soil and water conservation. It is complex, depending on soil and rainfall properties and initial and boundary conditions within the flow domain. During the last century, a great deal of effort has been invested to understand the physics of infiltration and to develop quantitative predictors of infiltration dynamics. Jean-Yves Parlange and Wilfried Brutsaert have made seminal contributions, especially in the area of infiltration theory and related analytical solutions to the flow equations. This review retraces the landmark discoveries and the evolution of the conceptual approaches and the mathematical solutions applied to the problem of infiltration into porous media, highlighting the pivotal contributions of Parlange and Brutsaert. A historical retrospective of physical models of infiltration is followed by the presentation of mathematical methods leading to analytical solutions of the flow equations. This review then addresses the time compression approximation developed to estimate infiltration at the transition between preponding and postponding conditions. Finally, the effects of special conditions, such as the presence of air and heterogeneity in soil properties, on infiltration are considered.

Chinese vegetative materia medica in a venereological treatise by Jean Astruc from 1740.

PubMed

Drobnik, Jacek

2016-07-01

Historical medical sources can be still queried for forgotten cures and remedies. Traditional Chinese medicine has dealt with lues venerea (syphilis) since the Five Dynasties period (10th century). Chinese indigenous materia medica and remedies recorded, studied or imported by the Europeans can reveal known or quite unknown medicinal plants. The studied Jean Astruc's work is a published ethnopharmacological survey carried out in Beijing in the 1730s and it deserves a modern interpretation. This is the first proposal to identify historical Chinese medicinal plants listed in a scarcely known medical treatise De Morbis venereis… ('On venereal diseases…') by Jean Astruc from 1740. I searched for the current uses and position of the taxonomically identified herbal stock in both traditional Chinese and official medical knowledge, with special attention to syphilis. Chinese names of drugs and their botanical identities (originally expressed by means of pre-Linnaean polynomials, and now interpreted as accepted binomials) were independently cross-checked with younger till most recent taxonomical and ethnopharmacological sources. Plants and drugs identified this way were queried for their modern applications in traditional Chinese and official medicine with special attention to sexually transmitted diseases (STD) and other uses which are similar to the 18th-century understanding of venereology. For 24 items of medicinal stock, 34 medicinal plants have been identified or suspected: Acacia catechu, Achyranthes bidentata, Akebia quinata, Angelica dahurica, A. sinensis, Aquilaria sinensis, Aralia cordata, Aristolochia fangchi, Chaenomeles sinensis, Ch. speciosa, Clematis vitalba, Coix lacryma-jobi, Commiphora myrrha, Cydonia oblonga, Daemonorops draco, D. jenkinsiana, Dictamnus dasycarpus, Dryobalanops sumatrensis, Forsythia suspensa, Glycyrrhiza uralensis, Lonicera confusa, L. hypoglauca, L. japonica, Ligusticum striatum (=L. chuanxiong), Piper kadsura, Pterocarpus

Environment-Mediated Drug Resistance in Neuroblastoma

DTIC Science & Technology

2014-10-01

Neuroblastoma PRINCIPAL INVESTIGATOR: Yves A. DeClerck CONTRACTING ORGANIZATION... Neuroblastoma 5a. CONTRACT NUMBER 5b. GRANT NUMBER W81XWH-12-1-0571 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) DE CLERCK, YVES 5d. PROJECT...experiments have demonstrated that monocytes collaborate with MSC in inducing STAT3-dependent drug resistance in neuroblastoma . Further

[The market at the heart of the invention of the museum ? : Jean-Baptiste-Pierre Lebrun at the Louvre (1792-1802)].

PubMed

Guichard, Charlotte

2011-01-01

Before Vivant Denon, the dealer Jean-Baptiste-Pierre Lebrun played a crucial role in the creation of the Louvre collections, despite the revolutionary discourse which opposed the market to the museum. Lebrun's position as a polemicist is interpreted here as a strategy of self-presentation which made possible the controversial birth of the figure of the museum expert. With Lebrun, the Louvre imposed itself as a public space of artistic expertise, where values imported from the market - such as attributionism, materiality, and authenticity - became prominent in the evaluation of paintings.

[Jean-Jacques Rosseau the vitalist. The moralization of medical hygiene between diet and ethical food].

PubMed

Menin, Marco

2012-01-01

The historiographical prejudice that sees in Jean-Jacques Rousseau an implacable opponent of scientific knowledge has long prevented an objective evaluation of the important influence that medical thought exerted over his philosophy. The aim of this paper is to show not only Rousseau's familiarity with the most important expressions of eighteenth-century medical literature, but also his willingness to incorporate some medical suggestions in his philosophical and literary production. In the first part of this article, I try to show how Rousseau's sensibility theory presupposes precise medical ideals, related to Montpellier School of vitalism. In the second part, I stress how Rousseau's philosophy of alimentation (which has clear anthropological and political implications) can be regarded as a genuine application of an ambition typical of vitalism: to use medical hygiene, also and above all, for moral purpose.

Thermal Jeans Fragmentation within ∼1000 au in OMC-1S

NASA Astrophysics Data System (ADS)

Palau, Aina; Zapata, Luis A.; Román-Zúñiga, Carlos G.; Sánchez-Monge, Álvaro; Estalella, Robert; Busquet, Gemma; Girart, Josep M.; Fuente, Asunción; Commerçon, Benoit

2018-03-01

We present subarcsecond 1.3 mm continuum ALMA observations toward the Orion Molecular Cloud 1 South (OMC-1S) region, down to a spatial resolution of 74 au, which reveal a total of 31 continuum sources. We also present subarcsecond 7 mm continuum VLA observations of the same region, which allow further study of fragmentation down to a spatial resolution of 40 au. By applying a method of “mean surface density of companions” we find a characteristic spatial scale at ∼560 au, and we use this spatial scale to define the boundary of 19 “cores” in OMC-1S as groupings of millimeter sources. We find an additional characteristic spatial scale at ∼2800 au, which is the typical scale of the filaments in OMC-1S, suggesting a two-level fragmentation process. We measured the fragmentation level within each core and find a higher fragmentation toward the southern filament. In addition, the cores of the southern filament are also the densest cores (within 1100 au) in OMC-1S. This is fully consistent with previous studies of fragmentation at spatial scales one order of magnitude larger, and suggests that fragmentation down to 40 au seems to be governed by thermal Jeans processes in OMC-1S.

Ivan Djaja (Jean Giaja)1 and the Belgrade School of Physiology

PubMed Central

Andjus, Pavle R.; Stojilkovic, Stanko S.; Cvijic, Gordana

2016-01-01

Summary The founder of physiology studies in the Balkans and the pioneer of research on hypothermia, Ivan Djaja (Jean Giaja) was born 1884 in L’Havre. Giaja gained his PhD at the Sorbonne in 1909. In 1910 he established the first Chair of Physiology in the Balkans and organized the first Serbian Institute for Physiology at the School of Philosophy of the University of Belgrade. He led this Institute for more than 40 subsequent years. His most notable papers were in the field of thermoregulation and bioenergetics. Djaja became member of the Serbian and Croatian academies of science and doctor honoris causa of Sorbonne. In 1952 for the seminal work on the behaviour of deep cooled warm blooded animals he becane associate member of the National Medical Academy in Paris. In 1955 the French Academy of Sciences elected him as associate member in place of deceased Sir Alexander Fleming. Djaja died in 1957 during a congress held in his honour. He left more than 200 scientific and other papers and the golden DaVincian credo “Nulla dies sine experimento”. His legacy was continued by several generations of researchers, the most prominent among them being Stefan Gelineo, Radoslav Andjus and Vojislav Petrović. PMID:21777022

La prévention des infections par le virus respiratoire syncytial

PubMed Central

Robinson, JL

2011-01-01

RÉSUMÉ L’infection par le virus respiratoire syncytial (VRS) est la principale cause d’infections des voies respiratoires inférieures chez les jeunes enfants. Le palivizumab, un anticorps monoclonal anti-VRS, réduit le taux d’hospitalisation des enfants à haut risque mais est très coûteux. Le présent document de principes remplace les trois précédents documents de principes de la Société canadienne de pédiatrie sur le sujet et est mis à jour principalement pour traiter des récentes modifications aux lignes directrices de l’American Academy of Pediatrics dans le contexte canadien. Il contient une analyse des publications ainsi que des recommandations au sujet de l’utilisation du palivizumab chez les enfants à haut risque

Nutrient status of the lowbush blueberry, Lac-Saint-Jean area, Quebec, Canada. [Vaccinium angustifolium

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bouchard, A.R.; Gagnon, M.J.

1987-01-01

The lowbush blueberry (Vaccinium angustifolium Ait.) is an important commercial crop of the Lac-Saint-Jean area (Quebec, Canada). The major blueberry fields are located on sandy soils relatively poor in available mineral nutrients. The nutrients originate from a thin organic layer found on the top of these sandy soils. The leaf mineral contents (N, P, K, Mg, Ca, Mn, Fe, Cu, Zn and B) were measured in five blueberry fields during 1984 and 1985. Soil pH and soil available P, K, and Mg were also assessed. The results show that the leaf mineral contents are generally adequate. However, K and Znmore » might be occasionally deficient when compared to the actual established standards. The available Mg in soil was significantly correlated with the leaf Mg concentration. The data also suggest that the influence of the pH following the burn pruning seems to influence the nutrition of this species.« less

Le stéréorestituteur Kelsh

USGS Publications Warehouse

Kelsh, H.T.

1949-01-01

Le ste??re??orestituteur Kelsh est un appareil de restitution a?? double projection base?? sur le principe des anaglyphes, comme le Multiplex par exemple, mais il a une plus grande pre??cision que ce dernier, vu que les ne??gatifs sont utilise??s directement pour la restitution, sans que l'on soit oblige?? de les re??duire au pre??alable. Une telle solution devient possible lorsque l'e??chelle de l'image plastique (mode??le) est au moins 7 fois plus grande que celle des cliche??s. L'appareil comprend un support reposant par 4 pieds sur la table a?? dessin. Sa partie supe??rieure porte, par l'interme??diaire de trois vis calantes, un cadre dans lequel les deux chambres de projection sont suspendues. Des leviers de commande, agissant sur les chambres, permettent d'introduire la base, le de??versement et les inclinaisons transversale et longitudinale. Les cliche??s conjugue??s ou des diapositifs sont directement place??s dans les chambres de projection munies d'objectifs. En projetant les deux cliche??s au moyen de couleurs comple??mentaires, l'observateur - muni de lunettes a?? verres colore??s (couleurs comple??mentaires) - observe l'image plastique audessus de la table a?? dessin, l'orientation relative des chambres ayant e??te?? e??tablie au pre??alable. Pour le report des points de l'image plastique sur la minute, l'ope??rateur dispose d'une tablette amovible a?? marque-repe??re lumineuse qu'il de??place a?? la main et dont la hauteur au-dessus de la table a?? dessin peut e??tre commande??e par une molette. Pour e??tablir l'orientation absolue de l'image plastique, il suffit d'incliner convenablement le cadre de suspension a?? l'aide des vis calantes, l'orientation relative n'e??tant pas de??truite par cette ope??ration. Les deux cliche??s sont e??claire??s par des projecteurs munis d'une suspension a?? la cardan et relie??s a?? la tablette de restitution par des tiges te??lescopiques. Moyennant ce dispositif, l'e??clairage est concentre?? sur deux petites re

Causes de décès des patients infectés par le VIH dans le Centre tunisien

PubMed Central

Chelli, Jihène; Bellazreg, Foued; Aouem, Abir; Hattab, Zouhour; Mesmia, Hèla; Lasfar, Nadia Ben; Hachfi, Wissem; Masmoudi, Tasnim; Chakroun, Mohamed; Letaief, Amel

2016-01-01

La trithérapie antirétrovirale a contribué à une baisse considérable de la mortalité liée au VIH. Les causes de décès sont dominées par les infections opportunistes dans les pays en voie de développement et par les maladies cardiovasculaires et les cancers dans les pays développés. L’objectif était de déterminer les causes et les facteurs de risque de décès des patients infectés par le VIH dans le Centre Tunisien. Une étude transversale auprès des patients infectés par le VIH âgés de plus de 15 ans suivis à Sousse et à Monastir entre 2000 et 2014. Le décès était considéré lié au VIH si la cause était un évènement classant SIDA ou s’il était la conséquence d’une infection opportuniste d’étiologie indéterminée avec des CD4 < 50/mm3, non lié au VIH si la cause n’était pas un évènement classant SIDA, et de cause inconnue si aucune information n’était disponible. Deux cents treize patients, 130 hommes (61%) et 83 femmes (39%), d’âge moyen 40±11 ans ont été inclus. Cinquante quatre patients sont décédés, avec une mortalité de 5,4/100 patients-années. La mortalité annuelle a baissé de 5,8% en 2000-2003 à 2,3% en 2012-2014. La survie était de 72% à 5 ans et de 67% à 10 ans. Les décès étaient liés au VIH dans 70,4% des cas. Les causes de décès les plus fréquentes étaient la pneumocystose pulmonaire et la cryptococcose neuroméningée dans 6 cas (11%) chacune. Les facteurs de risque de décès étaient les antécédents d’infections opportunistes, la durée de la trithérapie antirétrovirale < 12 mois et le tabagisme. Le renforcement du dépistage, l’initiation précoce de la trithérapie antirétrovirale, et la lutte contre le tabagisme sont nécessaires afin de réduire la mortalité chez les patients infectés par le VIH en Tunisie. PMID:28292068

Le Châtelier reciprocal relations and the mechanical analog

NASA Astrophysics Data System (ADS)

Gilmore, Robert

1983-08-01

Le Châtelier's principle is discussed carefully in terms of two sets of simple thermodynamic examples. The principle is then formulated quantitatively for general thermodynamic systems. The formulation is in terms of a perturbation-response matrix, the Le Châtelier matrix [L]. Le Châtelier's principle is contained in the diagonal elements of this matrix, all of which exceed one. These matrix elements describe the response of a system to a perturbation of either its extensive or intensive variables. These response ratios are inverses of each other. The Le Châtelier matrix is symmetric, so that a new set of thermodynamic reciprocal relations is derived. This quantitative formulation is illustrated by a single simple example which includes the original examples and shows the reciprocities among them. The assumptions underlying this new quantitative formulation of Le Châtelier's principle are general and applicable to a wide variety of nonthermodynamic systems. Le Châtelier's principle is formulated quantitatively for mechanical systems in static equilibrium, and mechanical examples of this formulation are given.

Le Figaro. Revised.

ERIC Educational Resources Information Center

Crawford, Linda

These instructional materials are designed for students with some French reading skills and vocabulary in late beginning or early intermediate senior high school French. The objectives are to introduce students to a French newspaper, "Le Figaro," and develop reading skills for skimming, gathering specific information, and relying on cognates. The…

Rectification of thermal fluctuations in ideal gases.

PubMed

Meurs, P; Van den Broeck, C; Garcia, A

2004-11-01

We calculate the systematic average speed of the adiabatic piston and a thermal Brownian motor, introduced by C. Van den Broeck, R, Kawai and P. Meurs [Phys. Rev. Lett. 93, 090601 (2004)], by an expansion of the Boltzmann equation and compare with the exact numerical solution.

Reduction of forecast uncertainty in the context of hydropower production: a case study for two catchment in Lac-St-Jean, Canada

NASA Astrophysics Data System (ADS)

Brisson, Cathy; Boucher, Marie-Amélie; Latraverse, Marco

2014-05-01

locations (intermediate location and downstream) leads to improved forecasts, as measured by the Nash-Sutcliffe efficiency criterion. The parameter sets thus determined best represent the phenomena of exchange and runoff in the watershed. Second, this study aims at reducing the uncertainty associated to the evacuation function for the Bonnard channel as well as the time delay related to this transfer. Instead of using a fixed 2-day time delay for the transfer, it was attempted to represent the channel in the hydrological model CEQUEAU and compute the time delay from this model. The results show that hydrological modelling does not improve the results and that the 2-day time delay is adequate, especially for first days of opening and few days after closure of the gate. In addition, this research shows that the evacuation function of Bonnard spillway is inexact for large streamflows. It is considered the main source of uncertainty for the prediction of inflows to the reservoirs. We also show that the evacuated streamflows can be successfully corrected by hydrological modelling. This case study shows that a careful revision of the inflow forecasting process for those important watersheds can help reduce predictive uncertainty. Although the application is specific to the Lac-St-Jean area, we believe that our experience could serve other users and water managers with similar issues regarding inflow uncertainty. Reference Morin, G., J.-P. Fortin, J.-P. Lardeau, W. Sochanska and S. Paquette. 1981. Modèle CEQUEAU : Manuel d'utilisation. Rapport de recherche no R-93, INRS-Eau, Sainte-Foy

Spondylodiscite granulomateuse: surtout la tuberculose mais ne pas omettre le lymphome

PubMed Central

Zinebi, Ali; Rkiouak, Adil; Akhouad, Yousef; Reggad, Ahmed; Kasmy, Zohour; Boudlal, Mostafa; Lho, Abdelhamid Nait; Rabhi, Moncef; Sinaa, Mohamed; Ennibi, Khalid; Chaari, Jilali

2016-01-01

Les douleurs lombaires relèvent d'étiologies multiples dont le diagnostic peut être source de grandes difficultés. Le lymphome rachidien primitif est rare et son diagnostic nécessite une biopsie souvent scanoguidée. Un homme de 30 ans, était hospitalisé pour lombalgies inflammatoires évoluant dans un contexte d'altération de l'état général avec à l'examen des douleurs à la palpation des apophyses épineux L2L3, sans syndrome tumoral périphérique. Le bilan biologique montrait un syndrome inflammatoire. Le bilan morphologique était en faveur d'une spondylodiscite. La première biopsie montrait une ostéite granulomateuse. L'aggravation clinique et radiologique sous anti bacillaire a mené à reconsidérer le diagnostic et la deuxième biopsie confirme le diagnostic du lymphome. Le diagnostic de tuberculose osseuse en particulier vertébrale nécessite une confirmation bactériologique et ou histologique pour ne pas méconnaître un lymphome osseux primitif. PMID:28292061

Anatomy of the Le Fort I segment: Are arterial variations a potential risk factor for avascular bone necrosis in Le Fort I osteotomies?

PubMed

Bruneder, Simon; Wallner, Jürgen; Weiglein, Andreas; Kmečová, Ĺudmila; Egger, Jan; Pilsl, Ulrike; Zemann, Wolfgang

2018-05-02

Osteotomies of the Le Fort I segment are routine operations with low complication rates. Ischemic complications are rare, but can have severe consequences that may lead to avascular bone necrosis of the Le Fort I segment. Therefore the aim of this study was to investigate the blood supply and special arterial variants of the Le Fort I segment responsible for arterial hypoperfusion or ischemic avascular necrosis after surgery. The arterial anatomy of the Le Fort I segment's blood supply using 30 halved human cadaver head specimens was analyzed after complete dissection until the submicroscopic level. In all specimens the arterial variants of the Le Fort I segment and also the arterial diameters measured at two points were evaluated. The typical known vascularization pattern was apparent in 90% of all specimens, in which the ascending palatine (D1: 1,2 mm ± 0,34 mm; D2: 0,8 mm ± 0,34 mm) and ascending pharyngeal artery (D1: 1,3 mm ± 0,58 mm; D2: <0,4 mm) were both supplying the Le Fort I segment. However in 10% of all specimens, the Le Fort I segment was dependent on the ascending pharyngeal artery alone and the missing ascending palatine artery was replaced with the anterior branch of the ascending pharyngeal artery (D1: 1,9 mm ± 0,32; D2: 1,0 mm ± 0,3 mm). This study is the first description of a special type of arterial variation of the Le Fort I segment. The type of this arterial variation, its clinical relevance and potential consequences are explained. Individuals with this special arterial anatomy may clinically be at a high risk for hypoperfusion and avascular segment necrosis after surgery. An individualized operation plan may prevent ischemic complications in at-risk patients. Copyright © 2018 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.

Les fluctuations supraconductrices dans le compose praseodyme-cerium-oxyde de cuivre

NASA Astrophysics Data System (ADS)

Renaud, Jacques

Ce travail etudie les fluctuations supraconductrices dans le compose supraconducteur a haute temperature critique dope aux electrons Pr2-xCe xCuO4+delta. La technique utilisee pour sonder ces fluctuations est le transport electrique DC dans le plan ab. Il s'agit, a notre connaissance, de la premiere etude de ce type dans la classe generale des supraconducteurs a haute temperature critique dopes aux electrons et, plus particulierement, dans Pr2-xCe xCuO4+delta. De plus, l'etude est effectuee pour trois regimes de dopage, soit sous-dope x = 0.135, dopage optimal x = 0.15 et surdope x = 0.17. Les echantillons etudies sont des couches minces d'epaisseur plus grande que 100 nm crues par ablation laser. Les mesures electriques DC effectuees dans ce travail sont la resistance en reponse lineaire et les courbes IV en reponse non lineaire en fonction de la temperature. La mise en oeuvre experimentale de ces mesures a necessite une grande attention au filtrage et aux effets de chauffage a haut courant. Nous montrons que, sans cette attention, les donnees experimentales sont toujours erronees dans le regime pertinent pour nos echantillons. Les resultats pour le dopage optimal x = 0.15 sont expliques de facon tres convaincante dans le cadre de fluctuations purement 2D. D'abord, le regime des fluctuations gaussiennes est tres bien decrit par le modele d'Aslamazov-Larkin en deux dimensions. Ensuite, le regime de fluctuations critiques, se trouvant a plus basse temperature que le regime gaussien, est tres bien decrit par la physique 2D de Kosterlitz-Thouless. Dans cette analyse, les deux regimes ont des temperatures critiques coherentes entre elles, ce qui semble confirmer ce scenario 2D. Une analyse des donnees dans le cadre de fluctuations 3D est exploree mais donne des conclusions incoherentes. Les resultats pour les autres dopages sont qualitativement equivalents avec le dopage optimal et permettent donc une explication purement 2D. Par contre, contrairement au dopage optimal

Les Hemorragies Gastroduodenales de Stress Chez le Brule Grave

PubMed Central

Siah, S.; Fouadi, F.E.; Ababou, K.; Nassim Sabah, T.; Ihrai, I.

2008-01-01

Summary Les Auteurs rapportent trois observations d'hémorragies gastroduodénales de stress chez le brûlé grave. Ils rappellent l'importance des mesures thérapeutiques qui doivent être prises chez le brûlé grave, comme le traitement du choc, du sepsis, des plaies et de la douleur, la nutrition entérale précoce et l'oxygénothérapie. Tout cela permet de réduire les facteurs de risque de survenue d'une hémorragie gastroduodénale de stress. PMID:21991137

Automated Verification of Design Patterns with LePUS3

NASA Technical Reports Server (NTRS)

Nicholson, Jonathan; Gasparis, Epameinondas; Eden, Ammon H.; Kazman, Rick

2009-01-01

Specification and [visual] modelling languages are expected to combine strong abstraction mechanisms with rigour, scalability, and parsimony. LePUS3 is a visual, object-oriented design description language axiomatized in a decidable subset of the first-order predicate logic. We demonstrate how LePUS3 is used to formally specify a structural design pattern and prove ( verify ) whether any JavaTM 1.4 program satisfies that specification. We also show how LePUS3 specifications (charts) are composed and how they are verified fully automatically in the Two-Tier Programming Toolkit.

Le Fort I Maxillary Advancement Using Distraction Osteogenesis

PubMed Central

Combs, Patrick D.; Harshbarger, Raymond J.

2014-01-01

Treatment of maxillary hypoplasia has traditionally involved conventional Le Fort I osteotomies and advancement. Advancements of greater than 10 mm risk significant relapse. This risk is greater in the cleft lip and palate population, whose anatomy and soft tissue scarring from prior procedures contributes to instability of conventional maxillary advancement. Le Fort I advancement with distraction osteogenesis has emerged as viable, stable treatment modality correction of severe maxillary hypoplasia in cleft, syndromic, and noncleft patients. In this article, the authors provide a review of current data and recommendations concerning Le Fort I advancement with distraction osteogenesis. In addition, they outline their technique for treating severe maxillary hypoplasia with distraction osteogenesis using internal devices. PMID:25383054

Specific role of LeMAN2 in the control of seed germination exposed by overexpression of the LeMAN3 gene in tomato plants.

PubMed

Belotserkovsky, Harel; Berger, Yael; Shahar, Ron; Wolf, Shmuel

2007-12-01

Endo-beta-mannanase is one of the key enzymes involved in the hydrolysis of the mannan-rich cell walls of tomato (Solanum lycopersicon) seeds. Two isoforms of endo-beta-mannanase have been characterized in tomato seeds: LeMAN2 is active in the micropylar area prior to germination and LeMAN1 is active after germination in all endosperm cells surrounding the cotyledons. To explore whether general mannanase activity in the endosperm cap is sufficient to promote germination, the gene encoding LeMAN3 was inserted into transgenic tomato plants under the control of a CaMV-35S promoter. Expression of LeMAN3 was evident in the endosperm cap and in the lateral endosperm of the transgenic seeds 10 min after imbibition. An activity test indicated increased activity of endo-beta-mannanase in the transgenic lines relative to the control line in all seed parts, during the first 20 h of imbibition. However, overexpression of LeMAN3 in transgenic seeds inhibited seed germination at both optimal and suboptimal temperatures. Detailed RT-PCR analyses revealed the transcription patterns of the genes encoding the various mannanase isoforms, and indicated a delay in LeMAN2 transcription in the endosperm cap of the transgenic seeds. Interestingly, tissue-print assays indicated similar mannanase activity in the micropylar areas for both transgenic and control seeds. These results indicate that overexpression of active endo-beta-mannanase in the endosperm cap is not sufficient to enable hydrolysis of the cell walls or to promote germination of tomato seeds. Cell-wall hydrolysis in these endosperm cells is under tight control and requires the specific activity of LeMAN2.

The scope of the LeChatelier Principle

NASA Astrophysics Data System (ADS)

George M., Lady; Quirk, James P.

2007-07-01

LeChatelier [Comptes Rendus 99 (1884) 786; Ann. Mines 13 (2) (1888) 157] showed that a physical system's “adjustment” to a disturbance to its equilibrium tended to be smaller as constraints were added to the adjustment process. Samuelson [Foundations of Economic Analysis, Harvard University Press, Cambridge, 1947] applied this result to economics in the context of the comparative statics of the actions of individual agents characterized as the solutions to optimization problems; and later (1960), extended the application of the Principle to a stable, multi-market equilibrium and the case of all commodities gross substitutes [e.g., L. Metzler, Stability of multiple markets: the hicks conditions. Econometrica 13 (1945) 277-292]. Refinements and alternative routes of derivation have appeared in the literature since then, e.g., Silberberg [The LeChatelier Principle as a corollary to a generalized envelope theorem, J. Econ. Theory 3 (1971) 146-155; A revision of comparative statics methodology in economics, or, how to do comparative statics on the back of an envelope, J. Econ. Theory 7 (1974) 159-172], Milgrom and Roberts [The LeChatelier Principle, Am. Econ. Rev. 86 (1996) 173-179], W. Suen, E. Silberberg, P. Tseng [The LeChatelier Principle: the long and the short of it, Econ. Theory 16 (2000) 471-476], and Chavas [A global analysis of constrained behavior: the LeChatelier Principle ‘in the large’, South. Econ. J. 72 (3) (2006) 627-644]. In this paper, we expand the scope of the Principle in various ways keyed to Samuelson's proposed means of testing comparative statics results (optimization, stability, and qualitative analysis). In the optimization framework, we show that the converse LeChatelier Principle also can be found in constrained optimization problems and for not initially “conjugate” sensitivities. We then show how the Principle and its converse can be found through the qualitative analysis of any linear system. In these terms, the Principle and

Ultrafast intramolecular charge transfer with N-(4-cyanophenyl)carbazole. Evidence for a LE precursor and dual LE + ICT fluorescence.

PubMed

Galievsky, Victor A; Druzhinin, Sergey I; Demeter, Attila; Mayer, Peter; Kovalenko, Sergey A; Senyushkina, Tamara A; Zachariasse, Klaas A

2010-12-09

The photophysics of N-(4-cyanophenyl)carbazole (NP4CN) was investigated by using absorption and fluorescence spectra, picosecond fluorescence decays, and femtosecond transient absorption. In the nonpolar n-hexane as well as in the polar solvent acetonitrile (MeCN), a locally excited (LE) state is detected, as a precursor for the intramolecular charge transfer (ICT) state. A LE → ICT reaction time τ(2) at 22 °C of 0.95 ps in ethyl cyanide (EtCN) and 0.32 ps in MeCN is determined from the decay of the LE excited state absorption (ESA) maximum around 620 nm. In the ESA spectrum of NP4CN in n-hexane at a pump-probe delay time of 100 ps, an important contribution of the LE band remains alongside the ICT band, in contrast to what is observed in EtCN and MeCN. This shows that a LE ⇄ ICT equilibrium is established in this solvent and the ICT reaction time of 0.5 ps is equal to the reciprocal of the sum of the forward and backward ICT rate constants 1/(k(a) + k(d)). In the photostationary S(0) → S(n) absorption spectrum of NP4CN in n-hexane and MeCN, an additional CT absorption band appears, absent in the sum of the spectra of its electron donor (D) and acceptor (A) subgroups carbazole and benzonitrile. This CT band is located at an energy of ∼4000 cm(-1) lower than for N-phenylcarbazole (NPC), due to the larger electron affinity of the benzonitrile moiety of NP4CN than the phenyl subunit of NPC. The fluorescence spectrum of NP4CN in n-hexane at 25 °C mainly consists of a structured LE emission, with a small ICT admixture, indicating that a LE → ICT reaction just starts to occur under these conditions. In di-n-pentyl ether (DPeE) and di-n-butyl ether (DBE), a LE emission is found upon cooling at the high-energy edge of the ICT fluorescence band, caused by the onset of dielectric solvent relaxation. This is not the case in more polar solvents, such as diethyl ether (DEE) and MeCN, in which a structureless ICT emission band fully overlaps the strongly quenched LE

Le schwannome malin du nerf grand sciatique chez l'enfant

PubMed Central

Lechqar, Maryem; Elbiache, Imad; Atarraf, Karima; Bouabdellah, Youssef; Afifi, My Abderahman

2012-01-01

Le schwannome malin est une tumeur très rare chez l'enfant (1 à 2% des tumeurs des tissus mous), elle se développe au dépend des cellules de schwanne. Dans ce travail, les auteurs rapportent un cas de schwannome malin développé au dépend du nerf grand sciatique. La radiographie de la cuisse de face et de profil était normale. L'imagerie par résonance magnétique a identifié une lésion le long du trajet du nerf grand sciatique. La tumeur a été réséquée en totalité emportant le nerf grand sciatique. L'examen anatomo-pathologique a confirmé le diagnostic. PMID:23133710

Le conflit fémoro-acétabulaire et la coxarthrose

PubMed Central

Zhang, Charlie; Li, Linda; Forster, Bruce B.; Kopec, Jacek A.; Ratzlaff, Charles; Halai, Lalji; Cibere, Jolanda; Esdaile, John M.

2015-01-01

Objectif Expliquer la présentation clinique, les observations à l’examen physique, les critères diagnostiques et les options de prise en charge du conflit fémoroacétabulaire (CFA). Sources des données Une recherche documentaire a été effectuée dans PubMed pour trouver des articles pertinents sur la pathogenèse, le diagnostic, le traitement et le pronostic du CFA. Message principal Depuis les dernières années, on reconnaît de plus en plus que le CFA est un précurseur potentiel et une étiologie importante des douleurs à la hanche dans la population adulte et de la coxarthrose idiopathique plus tard dans la vie. Le conflit fémoro-acétabulaire désigne un ensemble d’anomalies morphologiques osseuses de l’articulation de la hanche qui se traduit par un contact anormal durant le mouvement. Le CFA par effet came concerne une proéminence osseuse non sphérique du col fémoral proximal ou de la jonction tête-col. Le CFM par effet tenaille désigne une couverture acétabulaire excessive par-dessus la tête du fémur, qui peut se produire en raison de diverses variantes morphologiques. Les patients qui ont un CFA présentent une douleur inguinale antérieure chronique, profonde ou lancinante, le plus souvent en position assise, durant ou après une activité. Les patients peuvent aussi ressentir des douleurs occasionnelles aiguës durant l’activité. Il faut procéder à une anamnèse approfondie portant notamment sur l’incidence de traumatismes ou la fréquence de l’exercice. Il faut aussi faire un examen physique complet des hanches, de la région lombaire et de l’abdomen pour évaluer d’autres causes de douleurs inguinales antérieures. Le diagnostic de CFA est confirmé par radiographie. Le conflit fémoro-acétabulaire peut être pris en charge selon une approche conservatrice comportant du repos, la modification des activités, des médicaments et de la physiothérapie ou encore être traité par intervention chirurgicale. Conclusion

[The Gang of Six Demands more Freedom. Juvenile Offenders Interned in Saint-Jean-de-Dieu, Mid-20th Century].

PubMed

Desmeules, Martin; Thifault, Marie-Claude

In recent years, we have worked with many psychiatric records kept by the Archive Services of the Institut universitaire en santé mentale de Montréal (IUSMM). The proposed article is focused on the February 12th 1959 document Assemblée des médecins located within the records of six illegitimate children admitted to the Hôpital Saint-Jean-de-Dieu in the late 1950s. Our study, inspired by the work of historian Roy Porter and his approach from below, contributes to the historical discourse seeking to incorporate patient's voices, in this case, a gang of young offenders identified by a life course shaped by repeated institutional experience.

SCRaMbLE generates designed combinatorial stochastic diversity in synthetic chromosomes.

PubMed

Shen, Yue; Stracquadanio, Giovanni; Wang, Yun; Yang, Kun; Mitchell, Leslie A; Xue, Yaxin; Cai, Yizhi; Chen, Tai; Dymond, Jessica S; Kang, Kang; Gong, Jianhui; Zeng, Xiaofan; Zhang, Yongfen; Li, Yingrui; Feng, Qiang; Xu, Xun; Wang, Jun; Wang, Jian; Yang, Huanming; Boeke, Jef D; Bader, Joel S

2016-01-01

Synthetic chromosome rearrangement and modification by loxP-mediated evolution (SCRaMbLE) generates combinatorial genomic diversity through rearrangements at designed recombinase sites. We applied SCRaMbLE to yeast synthetic chromosome arm synIXR (43 recombinase sites) and then used a computational pipeline to infer or unscramble the sequence of recombinations that created the observed genomes. Deep sequencing of 64 synIXR SCRaMbLE strains revealed 156 deletions, 89 inversions, 94 duplications, and 55 additional complex rearrangements; several duplications are consistent with a double rolling circle mechanism. Every SCRaMbLE strain was unique, validating the capability of SCRaMbLE to explore a diverse space of genomes. Rearrangements occurred exclusively at designed loxPsym sites, with no significant evidence for ectopic rearrangements or mutations involving synthetic regions, the 99% nonsynthetic nuclear genome, or the mitochondrial genome. Deletion frequencies identified genes required for viability or fast growth. Replacement of 3' UTR by non-UTR sequence had surprisingly little effect on fitness. SCRaMbLE generates genome diversity in designated regions, reveals fitness constraints, and should scale to simultaneous evolution of multiple synthetic chromosomes. © 2016 Shen et al.; Published by Cold Spring Harbor Laboratory Press.

SCRaMbLE generates designed combinatorial stochastic diversity in synthetic chromosomes

PubMed Central

Shen, Yue; Stracquadanio, Giovanni; Wang, Yun; Yang, Kun; Mitchell, Leslie A.; Xue, Yaxin; Cai, Yizhi; Chen, Tai; Dymond, Jessica S.; Kang, Kang; Gong, Jianhui; Zeng, Xiaofan; Zhang, Yongfen; Li, Yingrui; Feng, Qiang; Xu, Xun; Wang, Jun; Wang, Jian; Yang, Huanming; Boeke, Jef D.; Bader, Joel S.

2016-01-01

Synthetic chromosome rearrangement and modification by loxP-mediated evolution (SCRaMbLE) generates combinatorial genomic diversity through rearrangements at designed recombinase sites. We applied SCRaMbLE to yeast synthetic chromosome arm synIXR (43 recombinase sites) and then used a computational pipeline to infer or unscramble the sequence of recombinations that created the observed genomes. Deep sequencing of 64 synIXR SCRaMbLE strains revealed 156 deletions, 89 inversions, 94 duplications, and 55 additional complex rearrangements; several duplications are consistent with a double rolling circle mechanism. Every SCRaMbLE strain was unique, validating the capability of SCRaMbLE to explore a diverse space of genomes. Rearrangements occurred exclusively at designed loxPsym sites, with no significant evidence for ectopic rearrangements or mutations involving synthetic regions, the 99% nonsynthetic nuclear genome, or the mitochondrial genome. Deletion frequencies identified genes required for viability or fast growth. Replacement of 3′ UTR by non-UTR sequence had surprisingly little effect on fitness. SCRaMbLE generates genome diversity in designated regions, reveals fitness constraints, and should scale to simultaneous evolution of multiple synthetic chromosomes. PMID:26566658

Structure post-flambée pour la locomotion d'un microrobot intratubulaire: comparaison modèle-expérience de l'effort de serrage dans le tube

NASA Astrophysics Data System (ADS)

Libersa, C.; Arsicault, M.; Lallemand, J.-P.

2002-12-01

Ces travaux entrent dans le cadre des études nécessaires à la mise au point d'une structure déformable actionnée par fils en alliage à mémoire de forme. L'application visée est son utilisation comme module de locomotion d'un microrobot intratubulaire autonome de type “ lombric ”. Un module est constitué d'un cadre élastique carré forcé en post-flambement sur un squelette rigide, de manière à obtenir deux configurations symétriques d'équilibre stable correspondant au premier mode de flambage. Le passage d'un état d'équilibre à l'autre est obtenu par la contraction de fils AMF éduqués disposés sur le cadre post-flambé. Un assemblage par juxtaposition de cinq modules identiques compose le corps du microrobot. Suivant un cycle de locomotion adéquat, chacun de ces actionneurs “ tout ou rien ” permet la prise d'appui sur les parois du tube ou l'allongement local nécessaire à l'avance du microrobot. Nous présentons ici les résultats obtenus lors d'un chargement transversal d'un module, et en particulier les courbes reliant l'effort de réaction et le déplacement du point en contact avec le tube. L'influence du serrage subit par le module sur le maintien du microrobot dans un tube vertical est déterminée. Les résultats expérimentaux obtenus sont comparés avec les résultats numériques.

Weighing the galactic disc using the Jeans equation: lessons from simulations

NASA Astrophysics Data System (ADS)

Candlish, G. N.; Smith, R.; Moni Bidin, C.; Gibson, B. K.

2016-03-01

Using three-dimensional stellar kinematic data from simulated galaxies, we examine the efficacy of a Jeans equation analysis in reconstructing the total disk surface density, including the dark matter, at the `Solar' radius. Our simulation data set includes galaxies formed in a cosmological context using state-of-the-art high-resolution cosmological zoom simulations, and other idealized models. The cosmologically formed galaxies have been demonstrated to lie on many of the observed scaling relations for late-type spirals, and thus offer an interesting surrogate for real galaxies with the obvious advantage that all the kinematical data are known perfectly. We show that the vertical velocity dispersion is typically the dominant kinematic quantity in the analysis, and that the traditional method of using only the vertical force is reasonably effective at low heights above the disk plane. At higher heights the inclusion of the radial force becomes increasingly important. We also show that the method is sensitive to uncertainties in the measured disk parameters, particularly the scalelengths of the assumed double exponential density distribution, and the scalelength of the radial velocity dispersion. In addition, we show that disk structure and low number statistics can lead to significant errors in the calculated surface densities. Finally, we examine the implications of our results for previous studies of this sort, suggesting that more accurate measurements of the scalelengths may help reconcile conflicting estimates of the local dark matter density in the literature.

How Do Le Fort-Type Fractures Present in a Pediatric Cohort?

PubMed

Macmillan, Alexandra; Lopez, Joseph; Luck, J D; Faateh, Muhammad; Manson, Paul; Dorafshar, Amir H

2018-05-01

Le Fort-type fractures are very rare in children, and there is a paucity of literature presenting their frequency and characteristics. The purpose of this study was to determine the etiology, frequency, and fracture patterns of children with severe facial trauma associated with pterygoid plate fractures in a pediatric cohort. We performed a retrospective cohort study of all children aged younger than 16 years with pterygoid plate and facial fractures who presented to our institute between 1990 and 2010. Patient charts and radiologic records were reviewed for demographic and fracture characteristics. Patients were categorized into 2 groups as per facial fracture pattern: non-Le Fort-type fractures (group A) and Le Fort-type fractures (group B). Other variables including dentition age, frontal sinus development, mechanism of injury, injury severity, and concomitant injuries were recorded. Univariate methods were used to compare groups. We identified 24 children; 25% were girls, and 20.8% were of nonwhite race. Most presented with Le Fort-type fracture patterns (group B, 66.7%). Age was significantly different between group A and group B (mean, 5.9 years and 9.9 years, respectively; P = .009). No significant differences in Injury Severity Score, rate of operative repair, and length of stay were found between groups. Most children with severe facial fractures and pterygoid plate fractures presented with Le Fort-type fracture patterns in our cohort. The mean age of children with Le Fort-type fractures was greater than in those with non-Le Fort-type patterns. However, Le Fort-type fractures did occur in younger children with deciduous and mixed dentition. Copyright © 2017 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.

La tuberculose pulmonaire et le tabac: à propos de 100 cas

PubMed Central

Janah, Hicham; Souhi, Hicham; Kouissmi, Hatim; Marc, Karima; Zahraoui, Rachida; Benamor, Jouda; Soualhi, Mona; Bourkadi, Jamal Eddine

2014-01-01

Le tabagisme et la tuberculose sont deux enjeux majeurs de santé publique au niveau mondial, en particulier dans les pays émergents. Pour déterminer les particularités cliniques, radiologiques, bactériologiques et thérapeutiques de la tuberculose pulmonaire chez les sujets tabagiques nous avons mené une étude prospective au service de phtisiologie de l'hôpital Moulay Youssef sur une période de 10 mois, portant sur 100 nouveaux cas de tuberculose pulmonaire, répartis en 2 groupes, 50 patients tabagiques: Groupe A et 50 patients non tabagiques: Groupe B. Tous nos patients étaient de sexe masculin, l’âge moyen était de 41 ans ± 12 chez le groupe A et de 36 ans ± 16 chez le groupe B. Le délai de consultation était plus long chez les tabagiques, la médiane était de 60j (30; 98) contre 40j (30; 60), la symptomatologie clinique était variable chez les deux groupes, dominée par les expectorations chez les tabagiques 96% contre 60%. Les lésions radiologiques étaient similaires chez les deux groupes ainsi que la charge bacillaire. Tous les patients ont été mis sous traitement antituberculeux. Après un mois du traitement, la Bacilloscopie était négative chez 50% du groupe A contre 66% chez le groupe B. la régression des lésions radiologiques était similaire chez les deux groupes. Le retard diagnostique et le retard de négativation des frottis sont les principales particularités de la tuberculose pulmonaire du sujet tabagique. Le sevrage tabagique doit faire partie intégrante de la prise en charge des patients atteints de tuberculose. PMID:25821545

La Recherche du Quark Top dans le Canal $e$ + Jets a D0 (in French)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lebrat, Jean-Francois

1996-05-01

Le travail de thèse qui est résumé ici a débuté en 1993, alors que l'existence du quark top n'avait pas encore été mise en évidence expérimentalement. Il se concentre sur la recherche du top dans l'un de ses modes de désintégration, le canal e + jets, et utilise l'ensemble des outils d'identication des particules et d'analyse développés par la collaboration DØ. L'analyse présentée ici est la première à utiliser le TRD (le Détecteur à Rayonnement de Transition, qui a été mis au point et fabriqué à Saclay) pour une meilleure identication de l'électron.Nous présenterons tout d'abord le quark top, enmore » décrivant la place qu'il occupe dans le modèle utilisé par les physiciens des particules, le Modèle Standard. Nous montrerons ainsi que l'existence du quark top était prédite par le modèle bien avant sa découverte, et indiquerons ainsi les raisons qui ont motivé notre analyse....« less

Primary Attraction of Ips latidens (LeConte) and Hylastes Gracilis LeConte (Coleoptera: Scolytidae) to High-Girdled Lodgepole Pine, Pinus Contorta var. Latifolia Engelmann

Treesearch

D.R. Miller; J.L. Madden; J.H. Borden

1986-01-01

In the absence of secondary attraction, 2 species of Scolytidae, Ips latidens (LeConte) and Hylastes gracilis LeConte, showed significant preference while in flight for high-girdled over non-girdled lodgepole pines, Pinus contorta var. latifolia Engelmann. In contrast, beetles in 2 genera...

[The film library of Sandoz].

PubMed

Lefebvre, Thierry

2014-10-01

During nearly forty years, the Cinémathèque Sandoz helped the initial formation of students and the training of doctors and pharmacists. Half a century after the produc tion of one of his most memorable films, Le Horla (Jean-Daniel Pollet), the author provides a brief history of those cultural sponsorship activites. It presents the main leaders of the cinémathèque et some of its iconic projets.

Insights: Simple Models for Teaching Equilibrium and Le Chatelier's Principle.

ERIC Educational Resources Information Center

Russell, Joan M.

1988-01-01

Presents three models that have been effective for teaching chemical equilibrium and Le Chatelier's principle: (1) the liquid transfer model, (2) the fish model, and (3) the teeter-totter model. Explains each model and its relation to Le Chatelier's principle. (MVL)

BOOK REVIEW: Jean-Charles Houzeau et son temps

NASA Astrophysics Data System (ADS)

Sterken, C.; Verhas, P.

2002-12-01

This is a wonderful book. It describes the life and work of Belgian astronomer Jean-Charles Houzeau (1820-1888) and, as the last three words of the title indicate, it has a broader focus including the social, industrial and scientific context of the second part of the 19th century. This is set in a very broad international social context including social revolutions in Belgium and France, and the abolition of slavery in the United States. The biography clearly shows that this hard-working man was driven by science and justice, by individualism and generosity, by humor and sentiment. The book is divided in four parts, each part is placed in its own historical context. The first part "The apprentice, the master and his disciples" describes Houzeau's childhood and young years, his early scientific career at the Observatory in Brussels, and his relationship with Adolphe Quetelet. The evolution of this relationship is very well documented: the turbulent revolutionary Houzeau versus cool, moderated and diplomatic royalist Quetelet, the observer versus the mathematician theorist. But both were very dedicated teachers: Quetelet established public courses and after the Revolution of 1830 he contributed to the foundation of the University of Brussels; Houzeau was the peripatetic teacher wherever place he was, also after his return to Belgium. The second part is "The politician" and deals with Houzeau's political ideas and revolutionary attitudes and their consequences. His revolutionary ideas, though, were not confined to politics only: he also severely criticised the paucity of high-precision observations collected at the Royal Observatory in his days. Because he participated at revolutionary meetings, Houzeau was fired from his position at the Observatory by the Minister of Interior Affairs Charles Rogier. Thus started his peripathetic life, covering observational work in astronomy, geography, geodesy and natural sciences in many places in Belgium and abroad. The third

Detection de la fin de la compaction des anodes par le son

NASA Astrophysics Data System (ADS)

Sanogo, Bazoumana

L'objectif de ce projet etait de developper un outil de controle en temps reel du temps de compaction en se servant du son genere par le vibrocompacteur pendant le formage des anodes crues. Ainsi, une application a ete developpee pour l'analyse des sons enregistres. Des essais ont ete realises avec differents microphones pour une meilleure qualite des mesures et un a ete choisi pour la suite du projet. De meme, differents tests ont ete realises sur des anodes de laboratoire ainsi que des anodes a l'echelle industrielle afin de mettre en place une methode pour la detection du temps optimal necessaire au formage des anodes. Les travaux au laboratoire de carbone a l'Universite du Quebec a Chicoutimi (UQAC) ont consiste a l'enregistrement de son des anodes fabriquees sur place avec differentes configurations; et a la caracterisation de certaines anodes de l'usine. Les anodes fabriquees au laboratoire sont reparties en deux groupes. Le premier regroupe les anodes pour la validation de notre methode. Ce sont des anodes produites avec des temps de compaction differents. Le laboratoire de carbone a l'UQAC est unique et il est possible de produire des anodes avec les memes proprietes que celles des anodes industrielles. Par consequent, la validation initialement prevue a l'usine a ete effectuee avec les anodes de laboratoire. Le deuxieme groupe a servi a etudier les effets des matieres premieres sur le temps de compaction. Le type de coke et le type de brai ont constitue les differentes variations dans ce deuxieme groupe. Quant aux tests et mesures a l'usine, ils ont ete realises en trois campagnes de mesure. La premiere campagne en juin 2014 a servi a standardiser et a trouver le meilleur positionnement des appareils pour les mesures, a regler le logiciel et a faire les premieres mesures. Une deuxieme campagne en mai 2015 a fait l'objet d'enregistrement de son en classant les anodes selon differents temps de compaction. La troisieme et derniere campagne en decembre 2015 a

Le domaine des co-infections et des maladies concomitantes du Réseau canadien pour les essais VIH des IRSC : lignes directrices canadiennes pour la prise en charge et le traitement de la co-infection par le VIH et l’hépatite C chez les adultes

PubMed Central

Hull, Mark; Giguère, Pierre; Klein, Marina; Shafran, Stephen; Tseng, Alice; Côté, Pierre; Poliquin, Marc; Cooper, Curtis

2014-01-01

HISTORIQUE : De 20 % à 30 % des Canadiens qui vivent avec le VIH sont co-infectés par le virus de l’hépatite C (VHC), lequel est responsable d’une morbidité et d’une mortalité importantes. La prise en charge du VIH et du VHC est plus complexe en raison de l’évolution accélérée de la maladie hépatique, du choix et des critères d’initiation de la thérapie antirétrovirale et du traitement anti-VHC, de la prise en charge de la santé mentale et des toxicomanies, des obstacles socioéconomiques et des interactions entre les nouvelles thérapies antivirales à action directe du VHC et les antirétroviraux OBJECTIF : Élaborer des normes nationales de prise en charge des adultes co-infectés par le VHC et le VIH dans le contexte canadien. MÉTHODOLOGIE : Le Réseau canadien pour les essais VIH des Instituts de recherche en santé du Canada a réuni un groupe d’experts possédant des compétences cliniques en co-infection par le VIH et le VHC pour réviser les publications à jour ainsi que les lignes directrices et les protocoles en place. Après une vaste sollicitation afin d’obtenir des points de vue, le groupe de travail a approuvé des recommandations consensuelles, qu’il a caractérisées au moyen d’une échelle de qualité des preuves fondée sur la classe (bienfaits par rapport aux préjudices) et sur la catégorie (degré de certitude). RÉSULTATS : Toutes les personnes co-infectées par le VIH et le VHC devraient subir une évaluation en vue de recevoir un traitement du VHC. Les personnes qui ne sont pas en mesure d’entreprendre un traitement du VHC devraient être soignées pour le VIH afin de ralentir l’évolution de la maladie hépatique. La norme de traitement du VHC de génotype 1 est un régime comprenant de l’interféron pégylé et de la ribavirine dosée en fonction du poids, associés à un inhibiteur de la protéase du VHC. Pour les génotypes 2 ou 3, une bithérapie classique est recommandée pendant 24 semaines s�

Rôle de l'hydrogène dans le procédé de purification du silicium par plasma thermique inductif

NASA Astrophysics Data System (ADS)

Erin, J.; Morvan, D.; Amouroux, J.

1993-03-01

The use of the thermal process for purification of silicon led to a material with the chemical purity required for phototovoltaic applications. In this paper, the various properties of ArH2 plasma mixtures are briefly reviewed and the effect of hydrogen percentage in an argon plasma used for melting and purifying silicon is pointed out. Physico-chemical analysis of the purified silicon showed that hydrogen diffused in the material and could passivate crystal defects by formation of stable chemical bonds such as Si-H. La technique de purification du silicium sous plasma thermique permet d'aboutir à un matériau de pureté chimique requise pour l'industrie photovoltaïque. Dans ce travail, nous soulignerons le rôle de l'hydrogène intervenant dans les propriétés du plasma en rappelant les caractéristiques des plasmas Ar-H2 utilisés pour fondre et purifier le silicium. Les caractéristiques physico-chimiques du silicium purifié montrent que l'hydrogène diffuse dans le matériau et est en mesure de cicatriser les défauts cristallins par formation de liaisons chimiques stables de type Si-H.

La prise en charge d’une clientèle

PubMed Central

Roy, Andréanne; Breton, Mylaine; Loslier, Julie

2016-01-01

Résumé Objectif Analyser les facteurs qui incitent les médecins de famille nouvellement autorisés à faire de la prise en charge d’une clientèle en première ligne. Type d’étude Devis mixte séquentiel : questionnaire en ligne auto-administré auprès de médecins de famille, suivi d’entrevues individuelles. Contexte La Montérégie, qui est la deuxième région la plus populeuse du Québec, et qui présente des zones rurales et urbaines. Participants Tous les médecins de famille détenant un poste en Montérégie et ayant moins de 10 années d’expérience ont été sollicités, soit 366 médecins. Parmi eux, 118 ont complété le questionnaire en ligne (taux de réponse de 32,2 %). Parmi les répondants, 10 médecins ayant des profils de prise en charge variés ont été sélectionnés pour les entrevues individuelles. Principaux paramètres à l’étude Le pourcentage de temps de travail consacré à la prise en charge, analysé en parallèle avec différents facteurs facilitants et barrières à la prise en charge aux niveaux contextuel, organisationnel, du médecin de famille et de la clientèle. Résultats Les principaux facteurs facilitant la prise en charge sont la relation médecin-patient, l’intérêt pour les activités cliniques liées à la prise en charge, les modèles de rôles positifs, la collaboration avec une infirmière et l’accès adéquat aux ressources, notamment en santé mentale. Les principales barrières sont l’ampleur des tâches administratives, l’intérêt pour une pratique polyvalente, l’expérience négative de la prise en charge lors de la formation, un sentiment n’inaptitude à l’égard de la prise en charge, la lourdeur de la clientèle et le manque de soutien en début de pratique. Conclusion Certaines pistes de solution pour inciter les nouveaux médecins de famille à prendre en charge une clientèle sont proposées. Des points d’amélioration au niveau de la formation médicale, du soutien

Retour vers le futur: l'expérience des patients et le lien avec la qualité, la sécurité et le rendement financier.

PubMed

Cochrane, Bonnie S; Hagins, Mitch; King, John A; Picciano, Gino; McCafferty, Maureen M; Nelson, Brian

2015-11-01

Au Canada, l'amélioration de l'expérience des patients est devenue une priorité des politiques de santé. Le perfectionnement et la normalisation des outils et systèmes pour surveiller les mesures de l'expérience des patients augmentent, tandis que la tendance vers une plus grande reddition de compte sur des améliorations durables et abordables se confirme. Pour de nombreux professionnels de la santé, ce phénomène fait foi d'un intérêt renouvelé pour les besoins et priorités fondamentaux des patients, après des décennies où les changements structurels et technologiques ont dominé les programmes de santé. Pour les leaders en santé canadiens, l'amélioration de l'expérience des patients comporte actuellement de grands défis et de belles possibilités. À cet égard, l'expérience des organisations partenaires du groupe Studer au Canada est à la fois pertinente et instructive. Ces organisations ont adopté un modèle, du nom de Evidence-Based Leadership (EBL, ou leadership fondé sur des données probantes), qui favorise et soutient l'harmonisation de l'ensemble des activités et des comportements, conformément à des objectifs organisationnels précis, y compris des améliorations mesurables de l'expérience des patients. Le présent article expose des études de cas d'organisations qui ont adopté l'EBL. Ces organisations ont réalisé des progrès rapides en matière d'indicateurs de l'expérience des patients, ainsi que dans des secteurs essentiels comme les résultats cliniques, la sécurité et le rendement financier. Les données émergentes sur les facteurs et processus qui sous-tendent ces améliorations sont également abordées. © 2015 Collège canadien des leaders en santé

Generalized Jeans' Escape of Pick-Up Ions in Quasi-Linear Relaxation

NASA Technical Reports Server (NTRS)

Moore, T. E.; Khazanov, G. V.

2011-01-01

Jeans escape is a well-validated formulation of upper atmospheric escape that we have generalized to estimate plasma escape from ionospheres. It involves the computation of the parts of particle velocity space that are unbound by the gravitational potential at the exobase, followed by a calculation of the flux carried by such unbound particles as they escape from the potential well. To generalize this approach for ions, we superposed an electrostatic ambipolar potential and a centrifugal potential, for motions across and along a divergent magnetic field. We then considered how the presence of superthermal electrons, produced by precipitating auroral primary electrons, controls the ambipolar potential. We also showed that the centrifugal potential plays a small role in controlling the mass escape flux from the terrestrial ionosphere. We then applied the transverse ion velocity distribution produced when ions, picked up by supersonic (i.e., auroral) ionospheric convection, relax via quasi-linear diffusion, as estimated for cometary comas [1]. The results provide a theoretical basis for observed ion escape response to electromagnetic and kinetic energy sources. They also suggest that super-sonic but sub-Alfvenic flow, with ion pick-up, is a unique and important regime of ion-neutral coupling, in which plasma wave-particle interactions are driven by ion-neutral collisions at densities for which the collision frequency falls near or below the gyro-frequency. As another possible illustration of this process, the heliopause ribbon discovered by the IBEX mission involves interactions between the solar wind ions and the interstellar neutral gas, in a regime that may be analogous [2].

Could Jean-Dominique Cassini see the famous division in Saturn's rings?

NASA Astrophysics Data System (ADS)

Lozi, Julien; Reess, Jean-Michel; Semery, Alain; Lhomé, Emilie; Jacquinod, Sophie; Combes, Michel; Bernardi, Pernelle; Andretta, Rémi; Motisi, Maxime; Bobis, Laurence; Kaftan, Emilie

2013-09-01

Nowadays, astronomers want to observe gaps in exozodiacal disks to confirm the presence of exoplanets, or even make actual images of these companions. Four hundred and fifty years ago, Jean-Dominique Cassini did a similar study on a closer object: Saturn. After joining the newly created Observatoire de Paris in 1671, he discovered 4 of Saturn's satellites (Iapetus, Rhea, Tethys and Dione), and also the gap in its rings. He made these discoveries observing through the best optics at the time, made in Italy by famous opticians like Giuseppe Campani or Eustachio Divini. But was he really able to observe this black line in Saturn's rings? That is what a team of optical scientists from Observatoire de Paris - LESIA with the help of Onera and Institut d'Optique tried to find out, analyzing the lenses used by Cassini, and still preserved in the collection of the observatory. The main difficulty was that even if the lenses have diameters between 84 and 239 mm, the focal lengths are between 6 and 50 m, more than the focal lengths of the primary mirrors of future ELTs. The analysis shows that the lenses have an exceptionally good quality, with a wavefront error of approximately 50 nm rms and 200 nm peak-to-valley, leading to Strehl ratios higher than 0.8. Taking into account the chromaticity of the glass, the wavefront quality and atmospheric turbulence, reconstructions of his observations tend to show that he was actually able to see the division named after him.

Sur la modélisation des supraconducteurs : le ``modèle de l'état critique'' de Bean, en trois dimensions

NASA Astrophysics Data System (ADS)

Bossavit, A.

1993-03-01

Macroscopic modelling of superconductors demands a substitution of some nonlinear behavior law for Ohm's law. For this, a version of Bean's “critical state” model, derived from the setting of a convex functional of the current density field, valid in dimension 3 without any previous assumption about the direction of currents, is proposed. It is shown how two standard three-dimensional finite element methods (“h-formulation” and “e-formulation”), once fitted with this model, can deal with situations were superconductors are present. La modélisation macroscopique des supraconducteurs suppose le remplacement de la loi d'Ohm par une loi de comportement non linéaire adéquate. On présente à cet effet une version du “modèle de Bean”, ou modèle de l'état critique, basée sur la construction d'une certaine fonctionnelle convexe du champ des densités de courant, qui est valable en dimension 3 sans hypothèses préalables sur la direction des courants. On montre comment adapter deux méthodes standards de calcul de courants de Foucault par élérnents finis en trois dimensions (“en h” et “en e”) à la présence de supraconducteurs, en incorporant ce modèle.

Amphibians and Reptiles of the state of Nuevo León, Mexico.

PubMed

Lemos-Espinal, Julio A; Smith, Geoffrey R; Cruz, Alexander

2016-01-01

We compiled a check list of the herpetofauna of Nuevo León. We documented 132 species (23 amphibians, 109 reptiles), representing 30 families (11 amphibians, 19 reptiles) and 73 genera (17 amphibians, 56 reptiles). Only two species are endemic to Nuevo León. Nuevo León contains a relatively high richness of lizards in the genus Sceloporus. Overlap in the herpetofauna of Nuevo León and states it borders is fairly extensive. Of 130 native species, 102 are considered species of Least Concern in the IUCN red list, four are listed as Vulnerable, five are listed as Near Threatened, and four are listed as Endangered. According to SEMARNAT, 78 species are not of conservation concern, 25 are subject to Special Protection, 27 are Threatened, and none are listed as in Danger of Extinction. Given current threats to the herpetofauna, additional efforts to understand the ecology and status of populations in Nuevo León are needed.

Amphibians and Reptiles of the state of Nuevo León, Mexico

PubMed Central

Lemos-Espinal, Julio A.; Smith, Geoffrey R.; Cruz, Alexander

2016-01-01

Abstract We compiled a check list of the herpetofauna of Nuevo León. We documented 132 species (23 amphibians, 109 reptiles), representing 30 families (11 amphibians, 19 reptiles) and 73 genera (17 amphibians, 56 reptiles). Only two species are endemic to Nuevo León. Nuevo León contains a relatively high richness of lizards in the genus Sceloporus. Overlap in the herpetofauna of Nuevo León and states it borders is fairly extensive. Of 130 native species, 102 are considered species of Least Concern in the IUCN red list, four are listed as Vulnerable, five are listed as Near Threatened, and four are listed as Endangered. According to SEMARNAT, 78 species are not of conservation concern, 25 are subject to Special Protection, 27 are Threatened, and none are listed as in Danger of Extinction. Given current threats to the herpetofauna, additional efforts to understand the ecology and status of populations in Nuevo León are needed. PMID:27408562

Cranial nerve injury after Le Fort I osteotomy.

PubMed

Kim, J-W; Chin, B-R; Park, H-S; Lee, S-H; Kwon, T-G

2011-03-01

A Le Fort I osteotomy is widely used to correct dentofacial deformity because it is a safe and reliable surgical method. Although rare, various complications have been reported in relation to pterygomaxillary separation. Cranial nerve damage is one of the serious complications that can occur after Le Fort I osteotomy. In this report, a 19-year-old man with unilateral cleft lip and palate underwent surgery to correct maxillary hypoplasia, asymmetry and mandibular prognathism. After the Le Fort I maxillary osteotomy, the patient showed multiple cranial nerve damage; an impairment of outward movement of the eye (abducens nerve), decreased vision (optic nerve), and paraesthesia of the frontal and upper cheek area (ophthalmic and maxillary nerve). The damage to the cranial nerve was related to an unexpected sphenoid bone fracture and subsequent trauma in the cavernous sinus during the pterygomaxillary osteotomy. Copyright © 2010 International Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

Le syndrome des enfants battus: aspects cliniques et radiologiques

PubMed Central

Jlalia, Zied; Znaigui, Talel; Smida, Mahmoud

2016-01-01

La maltraitance physique des enfants ou le syndrome des enfants battus est responsable de plus de 75.000 décès par an en France. Ce problème de santé publique reste sous diagnostiqué en Tunisie et dans le monde. Le chemin a été laborieux pour la reconnaissance du syndrome des enfants battus dans certaines sociétés même occidentales. Nous avons voulus exposer ce problème aux praticiens afin qu'il soit mieux diagnostiqué et pris en charge. La maltraitance physique des enfants est appelée à tort syndrome de Silverman qui ne regroupe en fait que les lésions squelettiques chez ces enfants tels que les fractures. Mots clés: Fracture, maltraitance, enfant, neuro-radiologie PMID:27642408

Nutrition chez le brûlé

PubMed Central

Perro, G.

2016-01-01

Summary La nutrition est un challenge chez le brûlé, paradigme de l’agressé. Les points importants sont les apports entéraux précoces par sonde gastrique voire post pyloriques, la position proclive > 30°, la surveillance du transit et sa régulation par gastro ou entéro-kinétiques, la surveillance du poids, la quantification des apports avec supplémentation parentérale en cas de retard protéino énergétique. Chez l’enfant, l’adhésion à l’alimentation est difficile, de même que chez le senior, où une évaluation nutritionnelle initiale dépiste souvent une dénutrition préexistante. Les compléments alimentaires seront largement prescrits chez les patients de gravité intermédiaire. Les obèses bénéficieront d’un régime hypocalorique et hyperprotidique. Chez l’insuffisant rénal non dialysé il convient de limiter les apports en potassium. En cas brûlure périnéale, on peut proposer soit une constipation de courte durée, soit la mise en place d’un entéro-collecteur, les indications de colostomie étant devenues rares. Les apports entéraux sont difficiles à gérer en cas de décubitus ventral pour SDRA. Chez le brûlé grave de réanimation, l’accent doit plus être mis sur la qualité des nutriments que sur leur quantité. Les anciennes formules d’estimation calorique conduisaient à une surnutrition difficile à administrer et en général mal tolérée; la quantification mesurée par calorimétrie indirecte ou estimée par la formule de Toronto est bien plus adaptée. Plus récemment, l’instauration d’une immunonutrition (supplémentation en vitamines et oligo-éléments, glutamine, arginine, acide Ω 3 et contrôle raisonné de la glycémie) a été proposée pour réduire le stress oxydatif et l’inflammation provoqués par l’accident. PMID:27857647

Historical sources about diseases, death and embalming regarding the family of Jean Antoine Michel Agar, Minister of Finance of Gioacchino Murat.

PubMed

Marinozzi, S; Gazzaniga, V; Giuffra, V; Fornaciari, G

2011-06-01

Among the mummies preserved in the Basilica of San Domenico Maggiore in Naples, there are the bodies of the wife and three children of Jean Antoine Michel Agar, Minister of Finance of Naple's Kingdom during the Monarchy of Joachim Murat (1808-1815). Between 1983 and 1987 paleopathological analyses were performed; in particular, X-ray examination allowed investigation of the health status of the Agar family members and reconstruction of the embalming processes used to preserve the bodies. In addition, an analysis of the historical and archival documents was carried out, to formulate hypotheses about the causes of death, demonstrating how these sources could become important instruments to obtain diagnoses and pathological histories.

CoLeMo: A Collaborative Learning Environment for UML Modelling

ERIC Educational Resources Information Center

Chen, Weiqin; Pedersen, Roger Heggernes; Pettersen, Oystein

2006-01-01

This paper presents the design, implementation, and evaluation of a distributed collaborative UML modelling environment, CoLeMo. CoLeMo is designed for students studying UML modelling. It can also be used as a platform for collaborative design of software. We conducted formative evaluations and a summative evaluation to improve the environment and…

Le(x) glycan mediates homotypic adhesion of embryonal cells independently from E-cadherin: a preliminary note.

PubMed

Handa, Kazuko; Takatani-Nakase, Tomoka; Larue, Lionel; Stemmler, Marc P; Kemler, Rolf; Hakomori, Sen-itiroh

2007-06-22

Le(x) glycan and E-cadherin (Ecad) are co-expressed at embryonal stem (ES) cells and embryonal carcinoma (EC) cells. While the structure and function of Ecad mediating homotypic adhesion of these cells have been well established, evidence that Le(x) glycan also mediates such adhesion is weak, despite the fact that Le(x) oligosaccharide inhibits the compaction process. To provide stronger evidence, we knocked out Ecad gene in EC and ES cells to establish F9 Ecad (-/-) and D3M Ecad (-/-) cells, which highly express Le(x) glycan but do not express Ecad at all. Both F9 Ecad (-/-) and D3M Ecad (-/-) cells displayed strong autoaggregation in the presence of Ca(2+), while PYS-2 cells, which express trace amount of Ecad and undetectable level of Le(x) glycan, did not display autoaggregation. In addition, F9 Ecad (-/-) and D3M Ecad (-/-) cells displayed strong adhesion to plates coated with Le(x) glycosphingolipid (III(3)FucnLc4Cer), in dose-dependent manner, in the presence of Ca(2+). Thus, ES or EC cells display autoaggregation and strong adhesion to Le(x)-coated plates in the absence of Ecad, further supporting the notion of Le(x) self-recognition (i.e., Le(x)-to-Le(x) interaction) in cell adhesion.

Conductivite dans le modele de Hubbard bi-dimensionnel a faible couplage

NASA Astrophysics Data System (ADS)

Bergeron, Dominic

Le modele de Hubbard bi-dimensionnel (2D) est souvent considere comme le modele minimal pour les supraconducteurs a haute temperature critique a base d'oxyde de cuivre (SCHT). Sur un reseau carre, ce modele possede les phases qui sont communes a tous les SCHT, la phase antiferromagnetique, la phase supraconductrice et la phase dite du pseudogap. Il n'a pas de solution exacte, toutefois, plusieurs methodes approximatives permettent d'etudier ses proprietes de facon numerique. Les proprietes optiques et de transport sont bien connues dans les SCHT et sont donc de bonne candidates pour valider un modele theorique et aider a comprendre mieux la physique de ces materiaux. La presente these porte sur le calcul de ces proprietes pour le modele de Hubbard 2D a couplage faible ou intermediaire. La methode de calcul utilisee est l'approche auto-coherente a deux particules (ACDP), qui est non-perturbative et inclue l'effet des fluctuations de spin et de charge a toutes les longueurs d'onde. La derivation complete de l'expression de la conductivite dans l'approche ACDP est presentee. Cette expression contient ce qu'on appelle les corrections de vertex, qui tiennent compte des correlations entre quasi-particules. Pour rendre possible le calcul numerique de ces corrections, des algorithmes utilisant, entre autres, des transformees de Fourier rapides et des splines cubiques sont developpes. Les calculs sont faits pour le reseau carre avec sauts aux plus proches voisins autour du point critique antiferromagnetique. Aux dopages plus faibles que le point critique, la conductivite optique presente une bosse dans l'infrarouge moyen a basse temperature, tel qu'observe dans plusieurs SCHT. Dans la resistivite en fonction de la temperature, on trouve un comportement isolant dans le pseudogap lorsque les corrections de vertex sont negligees et metallique lorsqu'elles sont prises en compte. Pres du point critique, la resistivite est lineaire en T a basse temperature et devient

No 129-L'exercice physique pendant la grossesse et le postpartum.

PubMed

Davies, Gregory A L; Wolfe, Larry A; Mottola, Michelle F; MacKinnon, Catherine

2018-02-01

Énoncer une directive canadienne visant à informer les fournisseurs de soins obstétricaux des répercussions, pour la mère, le fœtus et le nouveau-né, des exercices de conditionnement aerobique et musculaire pendant la grossesse. RéSULTATS ATTENDUS: Effets sur la morbidité maternelle, fœtale et néonatale et mesures de la forme physique maternelle. Une recherche sur MEDLINE des articles, publiés en anglais de 1966 à 2002, appartenant aux catégories suivantes : études sur le conditionnement aérobique et musculaire chez des femmes ne faisant pas jusque-là d'exercice et chez des femmes actives avant leur grossesse, ainsi que des études sur les répercussions du conditionnement aérobique et musculaire sur les issues précoces et tardives de la grossesse ou sur les issues néonatales; rapports de synthèse et méta-analyses portant sur l'exercice pendant la grossesse. Les résultats recueillis ont été revus par la Société des obstétriciens et gynécologues du Canada (Comité de la pratique clinique - obstétrique), avec la participation de la Société canadienne de physiologie de l'exercice, et ils ont été classés suivant les critères d'évaluation des preuves établis par le Groupe de travail canadien sur l'examen de santé périodique. VALIDATION: Cette directive a été approuvée par le Comité de pratique clinique - obstétrique de la SOGC, par le Comité exécutif et par le Conseil de la SOGC, ainsi que par le Conseil d'administration de la Société canadienne de physiologie de l'exercice. PARRAINé PAR: la Société des obstétriciens et gynécologues du Canada et par la Société canadienne de physiologie de l'exercice. Copyright © 2018. Published by Elsevier Inc.

Jan Potocki et le "Gothic Novel"

ERIC Educational Resources Information Center

Finne, Jacques

1970-01-01

Establishes a parallel between the supernatural and fantastic qualities of Le Comte Jan Potocki's literary works, and the English gothic novels by comparing the elements of terror, mysterious atmosphere, and the supernatural beings involved. (DS)

Le Chatelier--Right or Wrong?

ERIC Educational Resources Information Center

Helfferich, Friedrich G.

1985-01-01

Presents a class exercise designed to find out how well students understand the nature and consequences of the mass action law and Le Chatelier's principle as applied to chemical equilibria. The exercise relates to a practical situation and provides simple relations for maximizing equilibrium quantities not found in standard textbooks. (JN)

Le Planetaire (Around the World)

ERIC Educational Resources Information Center

Rebouillet, Andre; And Others

1977-01-01

This section, "Le Planetaire," contains an interview with Anne Slack on the American Association of Teachers of French and contemporary French culture, a review of a dictionary of familiar French for students, dates to remember, events of interest to French teachers and a general bibliography. (Text is in French.) (AMH)

LeChâtelier's Principle in the Sciences

NASA Astrophysics Data System (ADS)

Thomsen, Volker B. E.

2000-02-01

LeChâtelier's principle of chemical equilibrium is actually a very general statement about systems in equilibrium and their behavior when subjected to external force or stress. Although one almost never finds mention of his name or law in other sciences, analogous principles and concepts do exist. In this note we examine some of the similar forms taken by this chemical principle in the fields of physics, geology, biology, and economics. Lenz's law in physics is an example of electromagnetic equilibrium and the geological principle of isostatic uplift concerns mechanical equilibrium. Both are strictly consequences of conservation of energy. LeChâtelier's principle deals with thermodynamic equilibrium and involves both the first and second laws of thermodynamics. The concept of homeostasis in biology and the economic law of supply and demand are both equilibrium-like principles, but involve systems in the steady state. However, all these principles involve the stability of the system under consideration and the analogies presented may be useful in the teaching of LeChâtelier's principle.

Health monitoring of the Saint-Jean bridge of Bordeaux, France using fiber Bragg grating extensometers

NASA Astrophysics Data System (ADS)

Magne, Sylvain; Boussoir, Jonathan; Rougeault, Stephane; Marty-Dewynter, Veronique; Ferdinand, Pierre; Bureau, Lionel

2003-07-01

Most civil engineering structures have been built in the 50's and 60's and reach similar level of degradation accelerated by loading conditions and corrosion. In Europe, National Authorities and the European Commission promote Health Monitoring concepts, instrumentation of existing structures and help in the design of new durable structures of higher performance. In this context, the CEA-List has achieved a non-exclusive industrial transfer of its Bragg grating sensing technology for civil engineering applications to Hydrolog (French SME), supported by the European Community and the french ministry of Industry. In order to check the reliability and user-friendliness of this instrumentation, eleven spectrally-multiplexed Bragg grating-based extensometers, four FBG temperature sensors and an acquisition unit have been installed into the Saint-Jean bridge in Bordeaux, France with the help of the Infrastructure Regional Direction (DRE-Aquitaine) and the Bordeaux Authority (Communaute Urbaine de Bordeaux). A standardized loading of the bridge has been performed on October 29, 1001, with the purpose of correlating its mechanical reaction to loading conditions. Moreover, the equipment has been operating for one year to take into account the winter-summer cycle.

Transgenic studies reveal the positive role of LeEIL-1 in regulating shikonin biosynthesis in Lithospermum erythrorhizon hairy roots.

PubMed

Fang, Rongjun; Zou, Ailan; Zhao, Hua; Wu, Fengyao; Zhu, Yu; Zhao, Hu; Liao, Yonghui; Tang, Ren-Jie; Pang, Yanjun; Yang, Rongwu; Wang, Xiaoming; Qi, Jinliang; Lu, Guihua; Yang, Yonghua

2016-05-26

The phytohormone ethylene (ET) is a key signaling molecule for inducing the biosynthesis of shikonin and its derivatives, which are secondary metabolites in Lithospermum erythrorhizon. Although ETHYLENE INSENSITIVE3 (EIN3)/EIN3-like proteins (EILs) are crucial transcription factors in ET signal transduction pathway, the possible function of EIN3/EIL1 in shikonin biosynthesis remains unknown. In this study, by targeting LeEIL-1 (L. erythrorhizon EIN3-like protein gene 1) at the expression level, we revealed the positive regulatory effect of LeEIL-1 on shikonin formation. The mRNA level of LeEIL-1 was significantly up-regulated and down-regulated in the LeEIL-1-overexpressing hairy root lines and LeEIL-1-RNAi hairy root lines, respectively. Specifically, LeEIL-1 overexpression resulted in increased transcript levels of the downstream gene of ET signal transduction pathway (LeERF-1) and a subset of genes for shikonin formation, excretion and/or transportation (LePAL, LeC4H-2, Le4CL-1, HMGR, LePGT-1, LeDI-2, and LePS-2), which was consistent with the enhanced shikonin contents in the LeEIL-1-overexpressing hairy root lines. Conversely, LeEIL-1-RNAi dramatically repressed the expression of the above genes and significantly reduced shikonin production. The results revealed that LeEIL-1 is a positive regulator of the biosynthesis of shikonin and its derivatives in L. erythrorhizon hairy roots. Our findings gave new insights into the molecular regulatory mechanism of ET in shikonin biosynthesis. LeEIL-1 could be a crucial target gene for the genetic engineering of shikonin biosynthesis.

Le modele de Hubbard bidimensionnel a faible couplage: Thermodynamique et phenomenes critiques

NASA Astrophysics Data System (ADS)

Roy, Sebastien

Une etude systematique du modele de Hubbard en deux dimensions a faible couplage a l'aide de la theorie Auto-Coherente a Deux Particules (ACDP) dans le diagramme temperature-dopage-interaction-sauts permet de mettre en evidence l'influence des fluctuations magnetiques sur les proprietes thermodynamiques du systeme electronique sur reseau. Le regime classique renormalise a temperature finie pres du dopage nul est marque par la grandeur de la longueur de correlation de spin comparee a la longueur thermique de de Broglie et est caracterisee par un accroissement drastique de la longueur de correlation de spin. Cette croissance exponentielle a dopage nul marque la presence d'un pic de chaleur specifique en fonction de la temperature a basse temperature. Une temperature de crossover est alors associee a la temperature a laquelle la longueur de correlation de spin est egale a la longueur thermique de de Broglie. C'est a cette temperature caracteristique, ou est observee l'ouverture du pseudogap dans le poids spectral, que se situe le maximum du pic de chaleur specifique. La presence de ce pic a des consequences sur l'evolution du potentiel chimique avec le dopage lorsque l'uniformite thermodynamique est respectee. Les contraintes imposees par les lois de la thermodynamique font en sorte que l'evolution du potentiel chimique avec le dopage est non triviale. On demontre entre autres que le potentiel chimique est proportionnel a la double occupation qui est reliee au moment local. Par ailleurs, une derivation de la fonction de mise a l'echelle de la susceptibilite de spin a frequence nulle au voisinage d'un point critique marque sans equivoque la presence d'un point critique quantique en dopage pour une valeur donnee de l'interaction. Ce point critique, associe a une transition de phase magnetique en fonction du dopage a temperature nulle, induit un comportement non trivial sur les proprietes physiques du systeme a temperature finie. L'approche quantitative ACDP permet de

[LE cells in synovial fluid: prevalence and diagnostic usefulness in rheumatic diseases].

PubMed

Puszczewicz, Mariusz; Białkowska-Puszczewicz, Grazyna

2010-01-01

This study was undertaken to determine the prevalence of LE cells in synovial fluid and their importance for the diagnosis of rheumatic disease. Synovial fluid was obtained from 631 patients: 31 with systemic lupus erythematosus (SLE), 337 with rheumatoid arthritis (RA), 4 with Still's disease, 9 with systemic scleroderma (SS), 27 with the overlap syndrome (RA/SLE), 132 with ankylosing spondylitis (AS), 57 with Reiter's syndrome, and 34 with psoriatic arthritis (PA). The fluid was centrifuged, precipitate smears were done and were May-Grünwald-Giemsa stained for cytologic assessment. The supernatant was collected for antinuclear antibody (ANA) testing. Physicochemical and serologic properties of the synovial fluid were routinely determined. All synovial fluids demonstrated signs of inflammation. The presence of LE cells was ascertained in five patients with SLE and nine patients with the overlap syndrome. In these cases, LE cells were accompanied by ANA. In addition, hematoxylin bodies were revealed in SLE patients. LE cells were observed in 2.6% of patients with RA but were not accompanied by ANA. Patients with SS, Still's disease, AS, Reiter's syndrome, and PA tested negative for LE cells. It appears from these results that LE cells are rarely present in the synovial fluid of patients with rheumatic diseases. In contrast, they occur in more than 40% of patients with the overlap syndrome and may thus be regarded as important for the diagnosis of this condition.

Helen Primrose LeVesconte: occupational therapy clinician, educator, and maker of history.

PubMed

Friedland, Judith; Rais, Hadassah

2005-06-01

The Canadian history of our profession is not well known and our identity is thought to suffer as a result. Helen Primrose LeVesconte (7896-1982) is one pioneer in our development whose story has not been told. Our purpose is to explore LeVesconte's life and work in order to expand knowledge of our roots and thereby strengthen our identity. Using interpretive biography methods we draw on LeVesconte's own writings, articles written about her, and archival documents to describe turning point moments in her life and to display meaningful patterns in her work. LeVesconte's work as a clinician and her role and reputation as an educator, show her to have been a strong and visionary leader. Her views on the client's role, the importance of the therapist-client relationship, prevention, community-based programs, and vocational rehabilitation are of particular interest. Because LeVesconte educated over 1,850 students while director of the occupational therapy program at the University of Toronto, her influence has been felt throughout the country. Her perspective is compared to current practice; and questions are raised as to aspects of her legacy and philosophy that might now be reconsidered.

Suivi après le traitement du cancer du sein

PubMed Central

Sisler, Jeffrey; Chaput, Geneviève; Sussman, Jonathan; Ozokwelu, Emmanuel

2016-01-01

Résumé Objectif Offrir aux médecins de famille un résumé des recommandations fondées sur les données probantes pour guider les soins aux survivantes traitées pour le cancer du sein. Qualité des données Une recherche documentaire a été effectuée dans MEDLINE entre 2000 et 2016 à l’aide des mots-clés anglais suivants : breast cancer, survivorship, follow-up care, aftercare, guidelines et survivorship care plans, en se concentrant sur la revue des lignes directrices publiées récemment par les organismes nationaux de cancérologie. Les données étaient de niveaux I à III. Message principal Les soins aux survivantes comportent 4 facettes : surveillance et dépistage, prise en charge des effets à long terme, promotion de la santé et coordination des soins. La surveillance des récidives ne se traduit que par une mammographie annuelle, et le dépistage d’autres cancers doit suivre les lignes directrices basées sur la population. La prise en charge des effets à long terme du cancer et de son traitement aborde des problèmes courants tels la douleur, la fatigue, le lymphœdème, la détresse et les effets indésirables des médicaments, de même que les préoccupations à long terme comme la santé du cœur et des os. La promotion de la santé met en relief les bienfaits de l’activité chez les survivantes du cancer, avec l’accent mis sur l’activité physique. Les soins aux survivantes sont de meilleure qualité lorsque divers services et professionnels de la santé participent aux soins, et le médecin de famille joue un rôle important dans la coordination des soins. Conclusion Les médecins de famille sont de plus en plus souvent les principaux fournisseurs de soins de suivi après le traitement du cancer du sein. Le cancer du sein doit être considéré comme une affection médicale chronique, même chez les femmes en rémission, et les patientes profitent de la même approche que celle utilisée pour les autres affections chroniques en

Endocytosis in the Shiitake Mushroom Lentinula edodes and Involvement of GTPase LeRAB7▿

PubMed Central

Lee, Ming Tsung; Szeto, Carol Ying Ying; Ng, Tak Pan; Kwan, Hoi Shan

2007-01-01

Endocytosis is the process by which substrates enter a cell without passing through the plasma membrane but rather invaginate the cell membrane and form intracellular vesicles. Rab7 regulates endocytic trafficking between early and late endosomes and between late endosomes and lysosomes. LeRab7 in Lentinula edodes is strongly homologous to Rab7 in Homo sapiens. Receptors for activated C kinase-1 (LeRACK1) and Rab5 GTPase (LeRAB5) were isolated as interacting partners of LeRab7, and the interactions were confirmed by in vivo and in vitro protein interaction assays. The three genes showed differential expression in the various developmental stages of the mushroom. In situ hybridization showed that the three transcripts were localized in regions of active growth, such as the outer region of trama cells, and the subhymenium of the hymenophore of mature fruiting bodies and the prehymenophore of young fruiting bodies. The existence of endocytosis in the mycelium and hymenophores was confirmed by the internalization of FM4-64. LeRAB7 was partially colocalized with the AM4-64 and was located in the late endocytic pathway. This is the first report of the presence of endocytosis in homobasidiomycetes. LeRAB7, LeRAB5, and LeRACK1 may contribute to the growth of L. edodes and cell differentiation in hymenophores. PMID:17921351

Culpabilité chez les enfants victimes d’agression sexuelle : Le rôle médiateur des stratégies d’évitement sur l’anxiété et l’estime de soi

PubMed Central

Gauthier-Duchesne, Amélie; Hébert, Martine; Daspe, Marie-Ève

2017-01-01

Résumé Des études antérieures relèvent que le sentiment de culpabilité est un facteur associé aux répercussions de l’agression sexuelle (AS) chez les survivants adultes (Cantón-Cortés, Cantón, Justicia et Cortés, 2011). Toutefois, très peu d’études ont exploré le rôle potentiel du sentiment de culpabilité sur les symptômes chez les enfants victimes. L’objectif de cette recherche est d’étudier le rôle médiateur de l’évitement dans la relation entre le sentiment de culpabilité et les symptômes associés à l’AS (anxiété et estime de soi). L’échantillon est composé de 447 enfants victimes d'AS (319 filles et 128 garçons), âgés de 6 à 12 ans. Les résultats des analyses acheminatoires indiquent que les enfants révélant davantage de culpabilité par rapport à la situation d’AS présentent un niveau plus élevé d’anxiété et une plus faible estime d’eux-mêmes. Un effet indirect a également été observé et montre que le sentiment de culpabilité est lié à l’utilisation de stratégies d’évitement, qui en retour exacerbent les symptômes d’anxiété et contribuent à une plus faible estime de soi. Le modèle, qui s’ajuste aux données de manière équivalente pour les filles et les garçons, permet d’expliquer 24,4 % de la variance des symptômes d’anxiété et 11,2 % de la variance de l’estime de soi. Ces résultats laissent entendre que le sentiment de culpabilité pourrait constituer une cible d’intervention pertinente pour les enfants victimes d’AS. PMID:29445251

La prévention de l’infection par le virus respiratoire syncytial

PubMed Central

Samson, L

2009-01-01

L’infection par le virus respiratoire syncytial (VRS) est la principale cause d’infection des voies respiratoires inférieures chez les jeunes enfants et pour cette raison, bon nombre des prématurés et des enfants présentant d’autres facteurs de risque doivent être hospitalisés chaque année au Canada. Le palivizumab, un anticorps monoclonal anti-VRS, peut réduire le taux d’hospitalisation et la gravité de la maladie d’un petit groupe de prématurés ou de nourrissons à haut risque pendant leur première saison de VRS. Le présent document de principes contient une analyse des publications ainsi que des recommandations à l’intention des médecins canadiens au sujet de son utilisation chez les prématurés et les autres nourrissons à risque.

Involvement of LeMDR, an ATP-binding cassette protein gene, in shikonin transport and biosynthesis in Lithospermum erythrorhizon.

PubMed

Zhu, Yu; Lu, Gui-Hua; Bian, Zhuo-Wu; Wu, Feng-Yao; Pang, Yan-Jun; Wang, Xiao-Ming; Yang, Rong-Wu; Tang, Cheng-Yi; Qi, Jin-Liang; Yang, Yong-Hua

2017-11-13

Shikonin is a naphthoquinone secondary metabolite with important medicinal value and is found in Lithospermum erythrorhizon. Considering the limited knowledge on the membrane transport mechanism of shikonin, this study investigated such molecular mechanism. We successfully isolated an ATP-binding cassette protein gene, LeMDR, from L. erythrorhizon. LeMDR is predominantly expressed in L. erythrorhizon roots, where shikonin accumulated. Functional analysis of LeMDR by using the yeast cell expression system revealed that LeMDR is possibly involved in the shikonin efflux transport. The accumulation of shikonin is lower in yeast cells transformed with LeMDR-overexpressing vector than that with empty vector. The transgenic hairy roots of L. erythrorhizon overexpressing LeMDR (MDRO) significantly enhanced shikonin production, whereas the RNA interference of LeMDR (MDRi) displayed a reverse trend. Moreover, the mRNA expression level of LeMDR was up-regulated by treatment with shikonin and shikonin-positive regulators, methyl jasmonate and indole-3-acetic acid. There might be a relationship of mutual regulation between the expression level of LeMDR and shikonin biosynthesis. Our findings demonstrated the important role of LeMDR in transmembrane transport and biosynthesis of shikonin.

Approximation auto-coherente a deux particules, pseudogap et supraconductivite dans le modele de Hubbard attractif

NASA Astrophysics Data System (ADS)

Allen, Steve

2000-10-01

Dans cette these nous presentons une nouvelle methode non perturbative pour le calcul des proprietes d'un systeme de fermions. Notre methode generalise l'approximation auto-coherente a deux particules proposee par Vilk et Tremblay pour le modele de Hubbard repulsif. Notre methode peut s'appliquer a l'etude du comportement pre-critique lorsque la symetrie du parametre d'ordre est suffisamment elevee. Nous appliquons la methode au probleme du pseudogap dans le modele de Hubbard attractif. Nos resultats montrent un excellent accord avec les donnees Monte Carlo pour de petits systemes. Nous observons que le regime ou apparait le pseudogap dans le poids spectral a une particule est un regime classique renormalise caracterise par une frequence caracteristique des fluctuations supraconductrices inferieure a la temperature. Une autre caracteristique est la faible densite de superfluide de cette phase demontrant que nous ne sommes pas en presence de paires preformees. Les resultats obtenus semblent montrer que la haute symetrie du parametre d'ordre et la bidimensionalite du systeme etudie elargissent le domaine de temperature pour lequel le regime pseudogap est observe. Nous argumentons que ce resultat est transposable aux supraconducteurs a haute temperature critique ou le pseudogap apparait a des' temperatures beaucoup plus grandes que la temperature critique. La forte symetrie dans ces systemes pourraient etre reliee a la theorie SO(5) de Zhang. En annexe, nous demontrons un resultat tout recent qui permettrait d'assurer l'auto-coherence entre les proprietes a une et a deux particules par l'ajout d'une dynamique au vertex irreductible. Cet ajout laisse entrevoir la possibilite d'etendre la methode au cas d'une forte interaction.

Use of Mobile Testing System PeLe for Developing Language Skills

ERIC Educational Resources Information Center

Titova, Svetlana

2015-01-01

One of the objectives of this paper is to investigate the pedagogical impact of both the mobile testing system PeLe (Norway, HiST) and the enquiry-based learning approach on language skills development in the context of mobile-assisted learning. The research aims to work out a methodological framework of PeLe implementation into the language…

Pertinence de l'implantation de la filiere granule de bois pour le Quebec

NASA Astrophysics Data System (ADS)

Tremblay, Stephan

Les spécialistes avancent que le marché mondial de l'énergie en forte demande et en offre limitée nécessitera bientôt toutes les formes d'énergie disponibles. Le granulé de bois est une forme de bioénergie principalement utilisée pour le chauffage des bâtiments et pourrait être davantage considéré dans l'offre énergétique du Québec. Comme le Québec est un territoire où il fait froid et donc susceptible de pouvoir se tourner vers cette forme d'énergie, l'objectif de ce mémoire est d'en analyser les avantages. Pour ce faire, nous commencerons par démontrer la croissance des besoins énergétiques sur les plans national et international et dresser un portrait des différentes formes d'énergies consommées au Québec. Puisque la majorité des Québécois chauffent leurs bâtiments à l'hydroélectricité, nous analyserons à travers le plan d'approvisionnement d'Hydro-Québec le portrait de la production et de la consommation de cette forme d'énergie renouvelable. Cela nous permettra de constater le défi face à la gestion de surplus importants, sauf pendant la période hivernale, et ce faisant, l'obligation de la société d'État d'utiliser davantage ses centrales au gaz ou de se tourner vers l'importation de l'électricité. Dans la même lignée, un regard sera porté sur les perspectives d'utilisation de l'hydroélectricité sur les plans de la production d'aluminium, de l'exportation et de l'utilisation dans l'électrification des transports au Québec. Cette analyse se fera dans l'objectif de s'interroger sur la pertinence d'utiliser cette source d'énergie dans le chauffage plutôt que dans des secteurs plus créateurs de richesse. Nous poserons ensuite l'hypothèse que le granulé de bois pourrait être un bon substitut à une autre forme d'énergie utilisée dans le chauffage, soit le mazout. Avant de dresser un portrait de ce combustible fossile, nous ferons celui de la production et de la consommation de granulés sur les plans r

Connecting Instructional and Cognitive Aspects of an LE: A Study of the Global Seminar Project

ERIC Educational Resources Information Center

Savelyeva, Tamara

2012-01-01

My research problem is based on the lack of unifying conceptual cohesion between the discourses concerning cognitive and instructional aspects of learning environments (LE). I contrast that lack with practical developments of LE studies connected at the level of practical implementation and evaluation. Next, I briefly review the LE boundaries,…

Is subcranial Le Fort III plus Le Fort I osteotomy stable?

PubMed

Boos Lima, Fernanda Brasil Daura Jorge; Hochuli Vieira, Eduardo; Juergens, Philipp; Lima Junior, Sergio Monteiro

2017-12-01

The purpose of this study was to test whether associated subcranial Le Fort III (sLF III) and Le Fort I (LF I) osteotomies are stable after large advancements of the middle third of the face and maxilla. The authors designed a retrospective study and enrolled a sample of consecutive patients with midface hypoplasia treated with associated sLF III and LF I osteotomies in this IRB-approved study between September 2013 and February 2015. To test whether the long-term stability was satisfactory, the authors compared cephalometric changes from immediately after surgery to 18 months after surgery taken from multi-slice computed tomography using two different third-party imaging software programs. Statistical significance was set as P ≤ 0.05. The sample comprised 11 patients (mean age 23.84 ± 4.17 yr; 54% men). The mean advancement of the upper incisor immediately after surgery was 10.03 ± 1.6 mm. After 18 months, the position of the upper incisor did not vary significantly (10.18 ± 2.35 mm). All other cephalometric landmarks did not present statistically significant differences between immediately after and 18 months after surgery, with horizontal and vertical variations of less than one millimetre. This study supports that sLF III and LF I osteotomies are effective in maintaining stable horizontal and vertical skeletal positioning after surgery. Copyright © 2017 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.

Teaching Civilization with "Le Petit Nicholas."

ERIC Educational Resources Information Center

Pinet, Christopher

1983-01-01

Discusses the notions and concepts presented in "Le Petit Nicholas." Examines (1) how Goscinny presents his assimilation and understanding of French life to French children and adults and (2) how the books can be used as an introduction to French civilization at the intermediate level. (EKN)

In vitro DNA SCRaMbLE.

PubMed

Wu, Yi; Zhu, Rui-Ying; Mitchell, Leslie A; Ma, Lu; Liu, Rui; Zhao, Meng; Jia, Bin; Xu, Hui; Li, Yun-Xiang; Yang, Zu-Ming; Ma, Yuan; Li, Xia; Liu, Hong; Liu, Duo; Xiao, Wen-Hai; Zhou, Xiao; Li, Bing-Zhi; Yuan, Ying-Jin; Boeke, Jef D

2018-05-22

The power of synthetic biology has enabled the expression of heterologous pathways in cells, as well as genome-scale synthesis projects. The complexity of biological networks makes rational de novo design a grand challenge. Introducing features that confer genetic flexibility is a powerful strategy for downstream engineering. Here we develop an in vitro method of DNA library construction based on structural variation to accomplish this goal. The "in vitro SCRaMbLE system" uses Cre recombinase mixed in a test tube with purified DNA encoding multiple loxPsym sites. Using a β-carotene pathway designed for expression in yeast as an example, we demonstrate top-down and bottom-up in vitro SCRaMbLE, enabling optimization of biosynthetic pathway flux via the rearrangement of relevant transcription units. We show that our system provides a straightforward way to correlate phenotype and genotype and is potentially amenable to biochemical optimization in ways that the in vivo system cannot achieve.

Pictorial Format Display Evaluation

DTIC Science & Technology

1984-05-01

FIGR) under- Contract No. F33615-81-C-3610. Dr. John M. Reising served as Project Manager .with Capt. Carole Jean Kopala and, later, Major James S...Typo (SAM or AAA) Mode (Seahr, trac or launch) Air or Troak or Treat Type (MIG 21, MIK 23. SAM. or AAA" aa le Iunc Mode (Sara, trock or- lmxch) Clock...presentation (l pilot). Should come up automatically (I pilot). Airplane this smart should be able to fix these problems and just announce fix (1 pilot

Conception, fabrication et validation d'une presse a injection basse pression pour le procede des poudres metalliques =

NASA Astrophysics Data System (ADS)

Lamarre, Simon G.

Le moulage par injection a basse pression de poudre metallique est une technique de mise en forme de pieces de formes complexes. La poudre metallique est melangee avec des polymeres basse viscosite (ex. : cire) pour former un melange homogene a une temperature superieure a la temperature de fusion des polymeres. Pour faciliter l'injection dans la cavite du moule, la composition des melanges est ajustee pour diminuer la viscosite. D'une part, les melanges peu visqueux possedent une bonne moulabilite. D'autre part, le phenomene de la segregation se manifeste rapidement avec les melanges peu visqueux. Les machines commerciales sont munies d'un canal d'injection et d'une valve qui relient le reservoir de melange et la cavite du moule. Le melange reste stationnaire dans ces composantes entre deux sequences d'injection, ce qui le rend propice a la segregation. Plusieurs brevets tentent de resoudre ce probleme en utilisant des pompes et des canaux de recirculation. Ces composantes sont difficiles a nettoyer en raison de leur complexite. Une machine a injection basse pression a ete concue et fabriquee pour l'etude de l'aptitude au moulage des melanges de tres faible viscosite (ex. : 0.1 Pa˙s), qui tient compte du phenomene de segregation et des contraintes de nettoyage. Un piston d'injection puise le volume desire d'un reservoir. Ensuite, un mouvement lateral cisaille le melange a l'intersection entre le reservoir et le cylindre et bouche l'orifice de sortie du reservoir. Le cylindre est degage et peut recevoir le moule. A la suite de l'injection, le piston retourne a la position du reservoir et entre dans son orifice de sortie. Le melange residuel est retourne dans le reservoir, melange et desaere a nouveau. L'appareil a ete valide par des essais d'injectabilite avec un melange de poudre d'acier inoxydable et de liants a basse viscosite. Des essais d'injection ont montre que le melange contenant l'acide stearique a parcouru la plus grande distance dans le moule de forme

LE135, a retinoid acid receptor antagonist, produces pain through direct activation of TRP channels.

PubMed

Yin, Shijin; Luo, Jialie; Qian, Aihua; Yu, Weihua; Hu, Hongzhen

2014-03-01

Retinoids, through their activation of retinoic acid receptors (RARs) and retinoid X receptors, regulate diverse cellular processes, and pharmacological intervention in their actions has been successful in the treatment of skin disorders and cancers. Despite the many beneficial effects, administration of retinoids causes irritating side effects with unknown mechanisms. Here, we demonstrate that LE135 [4-(7,8,9,10-tetrahydro-5,7,7,10,10-pentamethyl-5H-benzo[e]naphtho[2,3-b][1,4]diazepin-13-yl)benzoic acid], a selective antagonist of RARβ , is a potent activator of the capsaicin (TRPV1) and wasabi (TRPA1) receptors, two critical pain-initiating cation channels. We performed to investigate the excitatory effects of LE135 on TRPV1 and TRPA1 channels expressed in HEK293T cells and in dorsal root ganglia neurons with calcium imaging and patch-clamp recordings. We also used site-directed mutagenesis of the channels to determine the structural basis of LE135-induced activation of TRPV1 and TRPA1 channels and behavioural testing to examine if pharmacological inhibition and genetic deletion of the channels affected LE135-evoked pain-related behaviours. LE135 activated both the capsaicin receptor (TRPV1) and the allyl isothiocyanate receptor (TRPA1) heterologously expressed in HEK293T cells and endogenously expressed by sensory nociceptors. Mutations disrupting the capsaicin-binding site attenuated LE135 activation of TRPV1 channels and a single mutation (K170R) eliminated TRPA1 activity evoked by LE135. Intraplantar injection of LE135 evoked pain-related behaviours. Both TRPV1 and TRPA1 channels were involved in LE135-elicited pain-related responses, as shown by pharmacological and genetic ablation studies. This blocker of retinoid acid signalling also exerted non-genomic effects through activating the pain-initiating TRPV1 and TRPA1 channels. © 2013 The British Pharmacological Society.

What to expect from dynamical modelling of galactic haloes - II. The spherical Jeans equation

NASA Astrophysics Data System (ADS)

Wang, Wenting; Han, Jiaxin; Cole, Shaun; More, Surhud; Frenk, Carlos; Schaller, Matthieu

2018-06-01

The spherical Jeans equation (SJE) is widely used in dynamical modelling of the Milky Way (MW) halo potential. We use haloes and galaxies from the cosmological Millennium-II simulation and hydrodynamical APOSTLE (A Project of Simulations of The Local Environment) simulations to investigate the performance of the SJE in recovering the underlying mass profiles of MW mass haloes. The best-fitting halo mass and concentration parameters scatter by 25 per cent and 40 per cent around their input values, respectively, when dark matter particles are used as tracers. This scatter becomes as large as a factor of 3 when using star particles instead. This is significantly larger than the estimated statistical uncertainty associated with the use of the SJE. The existence of correlated phase-space structures that violate the steady-state assumption of the SJE as well as non-spherical geometries is the principal source of the scatter. Binary haloes show larger scatter because they are more aspherical in shape and have a more perturbed dynamical state. Our results confirm that the number of independent phase-space structures sets an intrinsic limiting precision on dynamical inferences based on the steady-state assumption. Modelling with a radius-independent velocity anisotropy, or using tracers within a limited outer radius, result in significantly larger scatter, but the ensemble-averaged measurement over the whole halo sample is approximately unbiased.

"He sees the development of children's concepts upon a background of sociology": Jean Piaget's honorary degree at Harvard University in 1936.

PubMed

Hsueh, Yeh

2004-02-01

In the recent memory, Jean Piaget has been known as a cognitive developmental psychologist. But in 1936 when Harvard gave him his first honorary degree, he was recognized mainly as a sociologist. Why did Harvard honor him in 1936? Who knew his work well enough to nominate him? This article will address these questions by exploring archival documents from different sources. Evidence draws our attention to a broad social and intellectual endeavor in philanthropy, other social sciences, and especially industrial research that brought Piaget across the water. This article also attempts to interpret the circumstances of the nomination process inside and outside of Harvard University by using a theory of institutional design. It suggests that embodied in Harvard's honor of Piaget in 1936 was an idealistic act in social designing for a future society.

Nomenclatural notes on the Eurytomids (Chalcidoidea: Eurytomidae) described by Jean Brèthes housed in Museo Argentino de Ciencias Naturales "Bernardino Rivadavia".

PubMed

Gates, Michael W

2014-04-16

Ten Eurytomidae (Hymenoptera) parasitic wasp species described by Jean Brèthes and deposited in the Museo Argentino de Ciencias Naturales in Buenos Aires are treated and their nomenclature stabilized. The condition of the type material is described. Lectotypes are designated for Decatoma cecidosiphaga Brèthes, Prodecatoma parodii Brèthes, Eudecatoma opposita Brèthes, and Eurytoma caridei Brèthes. One new generic synonymy, Xanthosomodes Brèthes with Tetramesa Walker, n. syn., and five new combinations are proposed: Tetramesa albiangulata (Brèthes), n. comb.; Phylloxeroxenus caridei (Brèthes), n. comb.; Aximopsis vulgata (Brèthes), n. comb.; Proseurytoma parodii (Brèthes), n. comb.; and Bruchophagus opposita (Brèthes), n. comb. Sycophila paranensis Brèthes is declared incertae sedis.

Les bisphosphonates dans le traitement de l’ostéoporose

PubMed Central

Brown, Jacques P.; Morin, Suzanne; Leslie, William; Papaioannou, Alexandra; Cheung, Angela M.; Davison, Kenneth S.; Goltzman, David; Hanley, David Arthur; Hodsman, Anthony; Josse, Robert; Jovaisas, Algis; Juby, Angela; Kaiser, Stephanie; Karaplis, Andrew; Kendler, David; Khan, Aliya; Ngui, Daniel; Olszynski, Wojciech; Ste-Marie, Louis-Georges; Adachi, Jonathan

2014-01-01

Résumé Objectif Exposer l’efficacité et les risques du traitement par les bisphosphonates dans la prise en charge de l’ostéoporose et décrire les patients qui seraient de bons candidats aux congés thérapeutiques. Qualité des données Une recherche dans MEDLINE (PubMed, jusqu’au 31 décembre 2012) a permis de relever les publications pertinentes pour l’inclusion. La plupart des données probantes citées sont de niveau II (tirées d’essais non randomisés, de cohorte et d’autres essais comparatifs). Message principal L’efficacité des bisphosphonates de premier recours homologués pour la prévention des fractures a été éprouvée dans le cadre d’essais cliniques randomisés et contrôlés. Cependant, l’usage clinique répandu et prolongé des bisphosphonates a donné lieu à des rapports de manifestations indésirables rares, mais graves. L’ostéonécrose maxillaire et les fractures atypiques sous-trochantériennes ou diaphysaires du fémur seraient liées à l’emploi des bisphosphonates dans le traitement de l’ostéoporose, mais ces manifestations sont extrêmement rares et lorsqu’elles surviennent, elles sont accompagnées d’autres comorbidités ou de l’emploi concomitant de médicaments. Les congés thérapeutiques ne peuvent être envisagés que chez les patients à faible risque et dans un groupe restreint de patients dont le risque de fracture est modéré après un traitement de 3 à 5 ans. Conclusion Lorsque les bisphosphonates sont prescrits à des patients dont le risque de fracture est élevé, leur effet de prévention des fractures l’emporte de loin sur leurs torts potentiels. Chez les patients qui prennent des bisphosphonates depuis 3 à 5 ans, il faut réévaluer le besoin de poursuivre le traitement.

Architectural Kansei of ‘Wall’ in The Façade Design by Le Corbusier

NASA Astrophysics Data System (ADS)

Sendai, Shoichiro

The purpose of this paper is to discuss the modern architect Le Corbusier's architectural Kansei (sensibility) on wall in site environment through the analysis of his façade design, using Œuvres complètes (1910-1965, 8 vols., Les éditions d'architecture, Artemis, Zurich) and Le Corbusier Archives (1982-1984, 32 vols., Garland Publishing, Inc. and Fondation Le Corbusier, New York, London, Paris). At first, I arrange five façade types, according to the explanation by Le Corbusier ; ‘fenêtre en longueur (strip window)’, ‘pan de verre (glass wall)’, ‘brise-soleil (sun-breaker)’, ‘loggia’ and ‘claustra’. Through the analysis of the relationship between these types and the design process of each building, we find that Le Corbusier's façade design includes the affirmation and the negation of the ‘wall’ at the same time. In fact, the nature of façade modification during design process is divers: increase in transparency, decrease in transparency and spatialization of façade. That means, Le Corbusier studied the environmental condition by these façade types, and tried to realize the phenomenal openness. This trial bases on the function of architectural Kansei as correspondence between body and environment beyond the physical design.

Le kyste hydatique du cordon spermatique: une localisation exceptionnelle

PubMed Central

Hamdane, Mohamed Moncef; Bougrine, Fethi; Msakni, Issam; Dhaoui-Ghozzi, Amen; Bouziani, Ammar

2011-01-01

L’ hydatidose est une anthropo-zoonose due au développement chez l'homme de la forme larvaire du taenia Echinococcus granulosis. La plupart des kystes hydatiques se localisent dans le foie et les poumons. Le kyste hydatique du cordon spermatique est extrêmement rare avec seulement 4 cas rapportés dans la littérature. Les auteurs rapportent dans cet article un nouveau cas d'hydatidose du cordon spermatique. Il s'agissait d'un homme de 40 ans qui consultait pour des douleurs scrotales évoluant depuis huit mois. L'examen clinique a mis en évidence une tuméfaction mobile, inguino-scrotale, droite. L’échographie testiculaire a objectivé une hernie inguinale droite associée à deux kystes épididymaires bilatéraux. Le patient a été opéré pour cure de son hernie avec découverte en per-opératoire d'un kyste du cordon spermatique qui a été réséqué. L'examen anatomopathologique a conclu à une hydatidose du cordon spermatique. PMID:22384304

Involvement of LeMRP, an ATP-binding cassette transporter, in shikonin transport and biosynthesis in Lithospermum erythrorhizon.

PubMed

Zhu, Y; Chu, S-J; Luo, Y-L; Fu, J-Y; Tang, C-Y; Lu, G-H; Pang, Y-J; Wang, X-M; Yang, R-W; Qi, J-L; Yang, Y-H

2018-03-01

Shikonin and its derivatives are important medicinal secondary metabolites accumulating in roots of Lithospermum erythrorhizon. Although some membrane proteins have been identified as transporters of secondary metabolites, the mechanisms underlying shikonin transport and accumulation in L. erythrorhizon cells still remain largely unknown. In this study, we isolated a cDNA encoding LeMRP, an ATP-binding cassette transporter from L. erythrorhizon, and further investigated its functions in the transport and biosynthesis of shikonin using the yeast transformation and transgenic hairy root methods, respectively. Real-time PCR was applied for expression analyses of LeMRP and shikonin biosynthetic enzyme genes. Functional analysis of LeMRP using the heterologous yeast cell expression system showed that LeMRP could be involved in shikonin transport. Transgenic hairy roots of L. erythrorhizon demonstrated that LeMRP overexpressing hairy roots produced more shikonin than the empty vector (EV) control. Real-time PCR results revealed that the enhanced shikonin biosynthesis in the overexpression lines was mainly caused by highly up-regulated expression of genes coding key enzymes (LePAL, HMGR, Le4CL and LePGT) involved in shikonin biosynthesis. Conversely, LeMRP RNAi decreased the accumulation of shikonin and effectively down-regulated expression level of the above genes. Typical inhibitors of ABC proteins, such as azide and buthionine sulphoximine, dramatically inhibited accumulation of shikonin in hairy roots. Our findings provide evidence for the important direct or indirect role of LeMRP in transmembrane transport and biosynthesis of shikonin. © 2017 German Society for Plant Sciences and The Royal Botanical Society of the Netherlands.

Rôle de la radiothérapie dans le traitement de l'améloblastome: à propos de deux cas

PubMed Central

El Mazghi, Abderrahman; Bouhafa, Touria; El Kacemi, Hanan; Loukili, Kaoutar; Chbani, Laila; Kebdani, Taieb; Hassouni, Khalid

2014-01-01

L'améloblastome est une tumeur odontogène bénigne mais à pouvoir agressif et invasif local important. C'est une tumeur rare, elle représente 1% des tumeurs des maxillaires. Le rôle de la radiothérapie dans son traitement est actuellement démontré pour les tumeurs inopérables. Nous rapportons 2 cas d'améloblastomes mandibulaires chez deux patients qui ont bénéficié d'une radiothérapie externe à la dose de 60 Gy. L’évolution a été marquée par une rémission complète de la maladie dans les deux cas avec un recul de 2 et 5 ans. PMID:25722762

The Earth Summit: a vision shared. An interview with Jean-Claude Faby.

PubMed

Hoeffel, P H

1992-01-01

Interviewed by Development Forum, the director of UNCED's New York office, Jean-Claude Faby, who has been intimately involved in the negotiations preceding the Earth Summit, discusses his view of the process and expectations of global meeting. Faby explains that during the preparatory process, nongovernmental organizations (NGOs) have played an instrumental role. For example, women have raised issues concerning women, and their efforts are reflected in Agenda 21, the action plan of the Rio Declaration. Although describing the NGOs' critical assessment of the process as a health impatience, Faby notes that the issues to be confronted in Rio are some of the most complicated and vexing environmental and development problems facing the world community. Faby explains that the business community, an important player in the issues at hand, has also taken an active role in the negotiations. Faby acknowledges that the negotiations have witnessed a rift between North and South over the language of the document, a debate that will probably continue during the summit itself. Some of the issues of contention are military spending (a particularly concern of NGOs) and the North's high level of consumption, which the South insists must be addressed. Faby also discusses the issue of implementation and funding following the conclusion of the summit. Although implementation would require some $125 billion (a relatively modest figure), Faby expects that no neat funding package will emerge from Rio. In fact, funding will be one of the primary concerns of the Rio follow-up. Concerning the institutional follow-up of the summit, some are calling for the formation of a new institution, while others oppose such a move.

Microscopic Description of Le Chatelier's Principle

ERIC Educational Resources Information Center

Novak, Igor

2005-01-01

A simple approach that "demystifies" Le Chatelier's principle (LCP) and simulates students to think about fundamental physical background behind the well-known principles is presented. The approach uses microscopic descriptors of matter like energy levels and populations and does not require any assumption about the fixed amount of substance being…

Modelisation frequentielle de la permittivite du beton pour le controle non destructif par georadar

NASA Astrophysics Data System (ADS)

Bourdi, Taoufik

Le georadar (Ground Penetrating Radar (GPR)) constitue une technique de controle non destructif (CND) interessante pour la mesure des epaisseurs des dalles de beton et la caracterisation des fractures, en raison de ses caracteristiques de resolution et de profondeur de penetration. Les equipements georadar sont de plus en plus faciles a utiliser et les logiciels d'interpretation sont en train de devenir plus aisement accessibles. Cependant, il est ressorti dans plusieurs conferences et ateliers sur l'application du georadar en genie civil qu'il fallait poursuivre les recherches, en particulier sur la modelisation et les techniques de mesure des proprietes electriques du beton. En obtenant de meilleures informations sur les proprietes electriques du beton aux frequences du georadar, l'instrumentation et les techniques d'interpretation pourraient etre perfectionnees plus efficacement. Le modele de Jonscher est un modele qui a montre son efficacite dans le domaine geophysique. Pour la premiere fois, son utilisation dans le domaine genie civil est presentee. Dans un premier temps, nous avons valide l'application du modele de Jonscher pour la caracterisation de la permittivite dielectrique du beton. Les resultats ont montre clairement que ce modele est capable de reproduire fidelement la variation de la permittivite de differents types de beton sur la bande de frequence georadar (100 MHz-2 GHz). Dans un deuxieme temps, nous avons montre l'interet du modele de Jonscher en le comparant a d'autres modeles (Debye et Debye-etendu) deja utilises dans le domaine genie civil. Nous avons montre aussi comment le modele de Jonscher peut presenter une aide a la prediction de l'efficacite de blindage et a l'interpretation des ondes de la technique GPR. Il a ete determine que le modele de Jonscher permet de donner une bonne presentation de la variation de la permittivite du beton dans la gamme de frequence georadar consideree. De plus, cette modelisation est valable pour differents

LeRC in-house experimental research

NASA Technical Reports Server (NTRS)

Lyons, Valerie J.

1992-01-01

The topics covered include the following: LeRC in-house experimental research; combustion concepts; schedule for in-house experiments; lean premixed prevaporized combustion; comparisons of low NO(x) lean premixed/prevaporized data; rich burn/quick quench/lean burn (RQL); RQL combustion; fuel rich catalytic combustion; advanced diagnostics; and ceramic matrix liner test rig.

Standardissimo. Les limitations théoriques du Modèle Standard. Quelles réponses y apporter?

NASA Astrophysics Data System (ADS)

Renard, F. M.

Nous présentons I 'état du Modèle Standard des interactions fortes, faibles et électromagnétiques. Après une description rapide de ses 3 secteurs, secteur de jauge (radiation), secteur fermionique (matière) et secteur scalaire (génération des masses), nous insistons sur le grand nombre de paramètres libres et sur les choix arbitraires qu'il a fallu faire dans l'élaboration du modèle. Nous faisons ressortir les problèmes techniques non résolus et nous dressons la liste des questions fondamentales restées sans réponses. Nous passons ensuite en revue les idées et méthodes proposées pour répondre à ces questions. Elles utilisent essentiellement 3 voies différentes. La première consiste à requérir plus de symétrie (extension du modèle, symétrie Gauche-Droite, Grandes Unifications, Supersymétrie,...). La seconde contient les diverses alternatives au Modèle Standard impliquant des modifications dans certains secteurs (par exemple le secteur scalaire avec le modèle de la Technicouleur) ou de façon plus violente l'hypothèse d'une sous-structure des leptons, des quarks et des bosons W et Z eux-mêmes. Une dernière voie cherche à justifier les particularités du Modèle Standard et relier ses paramètres libres en se basant sur des principes de cohérence interne du modèle. Les conséquences observables de ces diverses approches sont dans chaque cas mentionnées.

LeCPK1, a Calcium-Dependent Protein Kinase from Tomato. Plasma Membrane Targeting and Biochemical Characterization1

PubMed Central

Rutschmann, Frank; Stalder, Urs; Piotrowski, Markus; Oecking, Claudia; Schaller, Andreas

2002-01-01

The cDNA of LeCPK1, a calcium-dependent protein kinase, was cloned from tomato (Lycopersicon esculentum Mill.). LeCPK1 was expressed in Escherichia coli and purified from bacterial extracts. The recombinant protein was shown to be a functional protein kinase using a synthetic peptide as the substrate (syntide-2, Km = 85 μm). Autophosphorylation of LeCPK1 was observed on threonine and serine residues, one of which was identified as serine-439. Kinase activity was shown to be Ca2+ dependent and required the C-terminal, calmodulin-like domain of LeCPK1. Two classes of high- and low-affinity Ca2+-binding sites were observed, exhibiting dissociation constants of 0.6 and 55 μm, respectively. LeCPK1 was found to phosphorylate the regulatory C-terminal domain of the plasma membrane H+-ATPase in vitro. A potential role in the regulation of proton pump activity is corroborated by the apparent colocalization of the plasma membrane H+-ATPase and LeCPK1 in vivo. Upon transient expression in suspension-cultured cells, a C-terminal fusion of LeCPK1 with the green fluorescent protein was targeted to the plasma membrane. Myristoylation of the LeCPK1 N terminus was found to be required for plasma membrane targeting. PMID:12011347

Performance du GeneXpert MTB/RIF® dans le diagnostic de la tuberculose extra-pulmonaire à Dakar: 2010-2015

PubMed Central

Diallo, Awa Ba; Kollo, Abdoulkader Issifi; Camara, Makhtar; Lo, Seynabou; Ossoga, Gedeon Walbang; Mbow, Moustapha; Karam, Farba; Niang, Mame Yacine Fall; Thiam, Aliou; Diawara, Awa Ndiaye; Mboup, Souleymane; Diallo, Aissatou Gaye

2016-01-01

Introduction Le défi des pays en voie de développement est la disponibilité de méthodes de diagnostic rapide et précis pour le management de la tuberculose. Des techniques moléculaires offrent cet avantage et nous avons utilisé le test GeneXpert MTB/RIF dans le diagnostic de la tuberculose extra-pulmonaire pour évaluer sa performance par rapport aux méthodes conventionnelles. Méthodes Entre 2010 et 2015, 544 échantillons cliniques extra-pulmonaires ont été recueillis et traitées par la microscopie, la culture et le GeneXpert. L'étude de la sensibilité aux antituberculeux a été effectué avec le MGIT 960. Le Génotype MTBDRplus a été utilisé pour confirmer les cas de résistance à la rifampicine détectés par le système GX. Résultats La population d'étude de 544 patients incluait 55,15% d'hommes et 44,85% de femmes. L'âge des patients variait entre 1 à 92 avec la majorité dans le groupe d'âge 18-45 ans. La sensibilité et la spécificité globale de la microscopie étaient de 43,86% et 98,36%, et pour le GeneXpert® 94,74% et 97,95% respectivement avec 95% IC. Deux résultats de résistance à la rifampicine discordants ont été trouvées entre le test GeneXpert et la méthode phénotypique. Les résultats du test MTBDRplus ont montré une concordance de 100% avec ceux du MGIT 960 pour les cas discordants de résistance à la rifampicine. Conclusion Cette étude a montré que le test GeneXpert a une plus grande sensibilité pour le diagnostic de routine de la tuberculose extra-pulmonaire et devrait être utilisé à la place de la microscopie. Les cas de résistance à la rifampicine détectés par le GeneXpert doivent être confirmés par d'autres tests moléculaires avant d'initier un traitement. PMID:28292091

LE135, a retinoid acid receptor antagonist, produces pain through direct activation of TRP channels

PubMed Central

Yin, Shijin; Luo, Jialie; Qian, Aihua; Yu, Weihua; Hu, Hongzhen

2014-01-01

Background and PurposeRetinoids, through their activation of retinoic acid receptors (RARs) and retinoid X receptors, regulate diverse cellular processes, and pharmacological intervention in their actions has been successful in the treatment of skin disorders and cancers. Despite the many beneficial effects, administration of retinoids causes irritating side effects with unknown mechanisms. Here, we demonstrate that LE135 [4-(7,8,9,10-tetrahydro-5,7,7,10,10-pentamethyl-5H-benzo[e]naphtho[2,3-b][1,4]diazepin-13-yl)benzoic acid], a selective antagonist of RARβ, is a potent activator of the capsaicin (TRPV1) and wasabi (TRPA1) receptors, two critical pain-initiating cation channels. Experimental ApproachWe performed to investigate the excitatory effects of LE135 on TRPV1 and TRPA1 channels expressed in HEK293T cells and in dorsal root ganglia neurons with calcium imaging and patch-clamp recordings. We also used site-directed mutagenesis of the channels to determine the structural basis of LE135-induced activation of TRPV1 and TRPA1 channels and behavioural testing to examine if pharmacological inhibition and genetic deletion of the channels affected LE135-evoked pain-related behaviours. Key ResultsLE135 activated both the capsaicin receptor (TRPV1) and the allyl isothiocyanate receptor (TRPA1) heterologously expressed in HEK293T cells and endogenously expressed by sensory nociceptors. Mutations disrupting the capsaicin-binding site attenuated LE135 activation of TRPV1 channels and a single mutation (K170R) eliminated TRPA1 activity evoked by LE135. Intraplantar injection of LE135 evoked pain-related behaviours. Both TRPV1 and TRPA1 channels were involved in LE135-elicited pain-related responses, as shown by pharmacological and genetic ablation studies. Conclusions and ImplicationsThis blocker of retinoid acid signalling also exerted non-genomic effects through activating the pain-initiating TRPV1 and TRPA1 channels. PMID:24308840

Rôle et limitations de la plasmonique pour le photovoltaïque solaire

NASA Astrophysics Data System (ADS)

Collin, Stéphane; Cattoni, Andrea

2018-02-01

À la fin des années 2000, la plasmonique a connu un engouement considérable au sein de la communauté photovoltaïque (PV) : le confinement de la lumière à l'échelle nanométrique devait offrir de nouveaux degrés de liberté dans la conception des cellules solaires, avec l'espoir de diminuer les coûts et d'augmenter les rendements des cellules solaires. Petit bilan après une décennie de recherches intensives.

Committees and supporting organizations

NASA Astrophysics Data System (ADS)

2011-09-01

Advisory Committee:Organizing Committee: Marcello Baldo (Catania)Takaharu Otsuka (Tokyo), co-chair George Bertsch (Seattle)Michael Urban (Orsay), co-chair Jean-Paul Blaizot (Saclay)Taiichi Yamada (Yokohama) Michel Girod (Bruyères-le-Châtel)Nguyen van Giai (Orsay) Hisashi Horiuchi (Osaka)Shinichiro Fujii (Tokyo) Umberto Lombardo (Catania)Jérôme Margueron (Orsay) Gerd Röpke (Rostock)Kouichi Hagino (Sendai) Hiroyuki Sagawa (Aizu)Yoshiko Kanada-En'yo (Kyoto) Piet Van Isacker (Caen) Enrico Vigezzi (Milano) IPN logo　　　　EFES logo　　　　CNRS logo　　　　ihp logo

Troubles psychotiques précipités par le mariage : étude de trois observations

PubMed Central

Jaweher, Masmoudi; Kammoun, Mohamed Faouzi; Inès, Feki; Imen, Baati; Rim, Sallami; Abdelaziz, Jaoua

2013-01-01

Le mariage est un évènement très investi dans notre culture arabo-musulmane. Il présente une situation à grande charge émotionnelle et ayant un vécu stressant. C'est ainsi qu'il peut être à l'origine de la décompensation de certains troubles psychiatriques. Ce moment particulier de déclenchement de la pathologie peut altérer significativement l'adaptation familiale et sociale du patient en question, le rendant dépendant en partie ou en totalité à une institution. Dans ce travail, nous proposons d’étudier certains facteurs psychiques, sociaux et culturels pouvant aboutir à la précipitation des manifestations psychotiques par le mariage. Il s'agit de l’étude de trois observations cliniques, deux hommes et une femme, hospitalisés dans le service de psychiatrie A du CHU Hédi Chaker de Sfax et qui ont développés des manifestations psychotiques de façon concomitante à leur mariage. La durée moyenne de survenue des crises a été de vingt ans, le diagnostic retenu a été celui de trouble bipolaire dans deux cas et d'une schizophrénie indifférenciée chez le troisième patient. L’évolution s'est faite vers une chronicisation de deux malades et une dépendance institutionnelle dans le troisième cas. La précipitation des troubles psychotiques par le mariage, reste un phénomène en relation intime avec les composantes culturelles, elles-mêmes sont déterminantes dans la prise en charge ultérieure de ces patients. PMID:23785551

Airborne pollen and spores of León (Spain)

NASA Astrophysics Data System (ADS)

Fernández-González, Delia; Suarez-Cervera, María; Díaz-González, Tomás; Valencia-Barrera, Rosa María

1993-06-01

A qualitative and quantitative analysis of airborne pollen and spores was carried out over 2 years (from September 1987 to August 1989) in the city of León. Slides were prepared daily using a volumetric pollen trap, which was placed on the Faculty of Veterinary Science building (University of León) 12m above ground-level. Fifty-one pollen types were observed; the most important of these were: Cupressaceae during the winter, Pinus and Quercus in spring, and Poaceae, Leguminosae and Chenopodiaceae in the summer. The results also showed the existence of a rich mould spore assemblage in the atmosphere. The group of Amerospores ( Penicillium, Aspergillus and Cladosporium) as well as Dictyospores ( Alternaria) were the most abundant; Puccinia was common in the air in August. Fluctuations in the total pollen and spores m3 of air were compared with meteorological parameters (temperature, relative humidity and rainfall). From the daily sampling of the atmosphere of León, considering the maximum and minimum temperature and duration of rainfall, the start of the pollen grain season was observed generally to coincide with a rise in temperature in the absence of rain.

Une fistule recto-vaginale rentrant dans le cadre d'un syndrome de Currarino

PubMed Central

Idrissi, Mounia Lakhdar; Babakhoya, Abdeladim; Bouabdellah, Youssef; Hida, Mostapha

2011-01-01

Le syndrome de Currarino (SC) est défini par une triade rassemblant une malformation ano-rectale, une agénésie sacrée et une tumeur pré-sacrée. Nous rapportons le cas d'une fille de 4 ans et demi ayant été admise en consultation de gastro-entérologie pédiatrique pour constipation avec issue de selle à travers un orifice vulvaire. La radiographie du rachis avait montré une agénésie sacrée. Le fistulo-scanner a mis en évidence une fistule recto-vaginale et l'IRM pelvienne a confirmé l'agénésie sacrée et a retrouvé une méningocèle antérieure. La découverte d'une malformation ano-rectale doit faire chercher une autre anomalie de la triade de Currarino. Cette affection, rare, nécessite une prise en charge médico-chirurgicale assez complexe. PMID:22384297

Considérations nosographiques sur le délire d'infestation parasitaire à travers trois observations cliniques

PubMed Central

Berhili, Nabil; Bout, Amine; Hlal, Hayat; Aarab, Chadya; Aalouane, Rachid; Rammouz, Ismail

2016-01-01

Le syndrome d'Ekbom, ou délire d'infestation parasitaire, est une pathologie rare, caractérisée par la conviction inébranlable d'avoir une peau infestée d'insectes ou de parasites. Il s'agit d'un délire monothématique à mécanisme hallucinatoire qui touche typiquement les femmes d’âge avancé. Nous rapportons les cas de trois patients qui présentent un délire d'infestation parasitaire dans des contextes cliniques différents. Le premier patient souffre d'un délire d'infestation isolé correspondant à la forme décrite par Karl Ekbom. Le deuxième cas présente un délire d'infestation secondaire, s'inscrivant dans le cadre d'une leuco-encéphalopathie de type CADASIL. Enfin, le troisième patient se présente dans un tableau évocateur d'un épisode dépressif avec une caractéristique psychotique qui intègre le délire d'infestation. Ces trois vignettes cliniques illustrent parfaitement le caractère trans-nosographique de ce syndrome ainsi que les difficultés de prise en charge de ces patients, tant au niveau de l'alliance thérapeutique que sur le plan des choix en matière de traitement pharmacologiques. PMID:27642468

La plastie en rail dans le traitement des brides rétractiles du creux poplite

PubMed Central

Achbouk, A.; Khales, A.; Bourra, K.; Tourabi, K.; Ababou, K.; Ihrai, H.

2011-01-01

Summary Les Auteurs décrivent le cas d’un patient âgé de 45 ans atteint de brûlures thermiques par flammes suite à la déflagration d’une bonbonne de gaz. Les lésions initiales intéressaient les quatre membres (en particulier, le genou) et le tronc. La prise en charge initiale a consisté en une excision-greffe précoce des membres. L’évolution a été marquée par la survenue de cicatrices hypertrophiques au niveau des zones non greffées et à la bordure de la greffe ainsi que la survenue de brides rétractiles. Devant l’handicap fonctionnel engendré par la bride à cause de la limitation importante de l’extension, le patient a été admis pour cure chirurgicale. Grâce à la technique en rail décrite, le patient a pu récupérer une fonction normale du genou. Les suites ont été simples avec une durée d’hospitalisation d’un mois. Le résultat esthétique est relativement satisfaisant. La technique en rail est un moyen parmi l’arsenal thérapeutique qui permet de traiter la bride du creux poplité. Sa simplicité, sa facilité technique et son résultat satisfaisant ainsi que ses suites simples permettent de la rendre une technique très prisée dans le traitement de ce type de bride. PMID:21991240

"Mathematics made no contribution to the public weal": why Jean Fernel (1497-1558) became a physician.

PubMed

Henry, John

2011-01-01

This paper offers a caution that emphasis upon the importance of mathematics in recent historiography is in danger of obscuring the historical fact that, for the most part, mathematics was not seen as important in the pre-modern period. The paper proceeds by following a single case study, and in so doing offers the first account of the mathematical writings of Jean Fernel (1497-1558), better known as a leading medical innovator of the 16th century. After establishing Fernel's early commitment to mathematics, and attempt to forge a career as a cosmographer, it goes on to explain his abandonment of mathematics for a career in medicine. The 'mathematization of the world picture' is usually explained in terms of the perceived usefulness of mathematics, but Fernel's case shows that for many pre-modern thinkers, mathematics was not regarded as a useful pursuit. The paper should serve as a reminder, therefore, that the take-up of mathematics by natural philosophers was by no means inevitable, but had to be carefully managed by early modern mathematical practitioners. The case of Fernel indicates that perhaps he was not the only would-be mathematical practitioner to abandon mathematics in favor of a calling that was more appreciated by contemporaries.

Jean-Martin Charcot and art: relationship of the "founder of neurology" with various aspects of art.

PubMed

Bogousslavsky, Julien; Boller, François

2013-01-01

Jean-Martin Charcot (1825-1893), the "father of neurology" in France and much beyond, was also the man who established academic psychiatry in Paris, differentiating it from clinical alienism. In his teaching, he used artistic representations from previous centuries to illustrate the historical developments of hysteria, mainly with the help of his pupil Paul Richer. Charcot liked to draw portraits (in particular, sketches of colleagues during boring faculty meetings and students' examinations), caricatures of himself and others, church sculptures, landscapes, soldiers, etc. He also used this skill in his clinical and scientific work; he drew histological or anatomic specimens, as well as patients' features and demeanor. His most daring artistic experiments were drawing under the influence of hashish. Charcot's tastes in art were conservative; he displayed no affinity for the avant-gardes of his time, including impressionism, or for contemporary musicians, such as César Franck or Hector Berlioz. Léon Daudet, son of Charcot's former friend and famous writer Alphonse Daudet, described Charcot's home as a pseudo-gothic kitsch accumulation of heteroclite pieces of furniture and materials. However, as Henry Meige wrote a few years after his mentor's death, Charcot the artist remains "inseparable from Charcot the physician." © 2013 Elsevier B.V. All rights reserved.

Microscopic Description of Le Châtelier's Principle

NASA Astrophysics Data System (ADS)

Novak, Igor

2005-08-01

The analysis based on microscopic descriptors (energy levels and their populations) is given that provides visualization of free energies and conceptual rationalization of Le Châtelier's principle. The misconception "nature favors equilibrium" is highlighted.

Etude thermo-hydraulique de l'ecoulement du moderateur dans le reacteur CANDU-6

NASA Astrophysics Data System (ADS)

Mehdi Zadeh, Foad

Etant donne la taille (6,0 m x 7,6 m) ainsi que le domaine multiplement connexe qui caracterisent la cuve des reacteurs CANDU-6 (380 canaux dans la cuve), la physique qui gouverne le comportement du fluide moderateur est encore mal connue de nos jours. L'echantillonnage de donnees dans un reacteur en fonction necessite d'apporter des changements a la configuration de la cuve du reacteur afin d'y inserer des sondes. De plus, la presence d'une zone intense de radiations empeche l'utilisation des capteurs courants d'echantillonnage. En consequence, l'ecoulement du moderateur doit necessairement etre etudie a l'aide d'un modele experimental ou d'un modele numerique. Pour ce qui est du modele experimental, la fabrication et la mise en fonction de telles installations coutent tres cher. De plus, les parametres de la mise a l'echelle du systeme pour fabriquer un modele experimental a l'echelle reduite sont en contradiction. En consequence, la modelisation numerique reste une alternative importante. Actuellement, l'industrie nucleaire utilise une approche numerique, dite de milieu poreux, qui approxime le domaine par un milieu continu ou le reseau des tubes est remplace par des resistances hydrauliques distribuees. Ce modele est capable de decrire les phenomenes macroscopiques de l'ecoulement, mais ne tient pas compte des effets locaux ayant un impact sur l'ecoulement global, tel que les distributions de temperatures et de vitesses a proximite des tubes ainsi que des instabilites hydrodynamiques. Dans le contexte de la surete nucleaire, on s'interesse aux effets locaux autour des tubes de calandre. En effet, des simulations faites par cette approche predisent que l'ecoulement peut prendre plusieurs configurations hydrodynamiques dont, pour certaines, l'ecoulement montre un comportement asymetrique au sein de la cuve. Ceci peut provoquer une ebullition du moderateur sur la paroi des canaux. Dans de telles conditions, le coefficient de reactivite peut varier de maniere

Caracterisation des melanges developpes pour le moulage basse pression des poudres metalliques (LPIM) =

NASA Astrophysics Data System (ADS)

Fareh, Fouad

Le moulage par injection basse pression des poudres metalliques est une technique de fabrication qui permet de fabriquer des pieces possedant la complexite des pieces coulees mais avec les proprietes mecaniques des pieces corroyees. Cependant, l'optimisation des etapes de deliantage et de frittage a ete jusqu'a maintenant effectuee a l'aide de melange pour lesquels la moulabilite optimale n'a pas encore ete demontree. Ainsi, la comprehension des proprietes rheologiques et de la segregation des melanges est tres limitee et cela presente le point faible du processus de LPIM. L'objectif de ce projet de recherche etait de caracteriser l'influence des liants sur le comportement rheologique des melanges en mesurant la viscosite et la segregation des melanges faible viscosite utilises dans le procede LPIM. Afin d'atteindre cet objectif, des essais rheologiques et thermogravimetriques ont ete conduits sur 12 melanges. Ces melanges ont ete prepares a base de poudre d'Inconel 718 de forme spherique (chargement solide constant a 60%) et de cires, d'agents surfactants ou epaississants. Les essais rheologiques ont ete utilises entre autre pour calculer l'indice d'injectabilite ?STV des melanges, tandis que les essais thermogravimetriques ont permis d'evaluer precisement la segregation des poudres dans les melanges. Il a ete demontre que les trois (3) melanges contenant de la cire de paraffine et de l'acide stearique presentent des indices alpha STV plus eleves qui sont avantageux pour le moulage par injection des poudres metalliques (MIM), mais segregent beaucoup trop pour que la piece fabriquee produise de bonnes caracteristiques mecaniques. A l'oppose, le melange contenant de la cire de paraffine et de l'ethylene-vinyle acetate ainsi que le melange contenant seulement de la cire de carnauba segregent peu voire pas du tout, mais possedent de tres faibles indices alphaSTV : ils sont donc difficilement injectables. Le meilleur compromis semble donc etre les melanges contenant de

Le Chatelier's Principle, Temperature Effects, and Entropy.

ERIC Educational Resources Information Center

Campbell, J. Arthur

1985-01-01

One of the most useful methods of understanding chemical equilibria is provided by Le Chatelier's principle. The relationships between this principle, temperature, and entropy are discussed. Tables with thermodynamic data for some net reactions commonly used to illustrate the principle and for reactions involving gases are included. (JN)

Hemoglobin Le Lamentin in the province of Albacete, Spain: Discovery of 32 cases.

PubMed

Martínez-López, Rosalina; Ropero, Paloma; Ballesteros Gallar, Cristina; Romero Román, Carlos; de la Fuente-Gonzalo, Félix; M Nieto, Jorge; Navarro Casado, Laura; González, Fernando A

2017-03-01

Hemoglobin Le Lamentin (α20(B1)His→Gln) is a ubiquitous variant that has been previously described in a small number of isolated patients. We report the incidental observation of Hb Le Lamentin in a large population from the province of Albacete, in southeastern Spain. Our study investigates possible reasons for the elevated number of carriers of this variant and its implications for the management of diabetes in our region. The subjects are 32 diabetic patients whose hemoglobin displayed an unusual peak while they were being tested for glycated hemoglobin at the laboratory of the University General Hospital of Albacete over a 3-year period. Measurements were made by high performance liquid chromatography using a Variant™ II Turbo Kit-2.0, and subsequently the samples of the 32 patients with anomalous peaks were sent to the Hospital Clínico San Carlos (Madrid, Spain) for molecular characterization of any Hb variants. Molecular studies revealed 31 out of 32 patients heterozygous for Le Lamentin, and in one of them, Hb City of Hope was associated with Hb Le Lamentin. The remaining patient was homozygous for the Le Lamentin mutation. Additionally, most patients were native to the northeastern half of the province of Albacete and were unrelated. Our study describes the largest finding to date of hemoglobin Le Lamentin in a sample of patients. The fact that our region has been perpetually depopulated, with a population that has remained stable in small localities over the centuries, may have favored the survival of the mutation. Since the presence of this variant underestimates the true value of glycated hemoglobin measured by HPLC, it is necessary to systematically review chromatograms. Copyright © 2016 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.

Modèle tridimensionnel pour coupler les équations magnétiques et électriques dans le cas de la magnétostatique

NASA Astrophysics Data System (ADS)

Piriou, F.; Razek, A.

1991-03-01

In this paper a 3D model for coupling of magnetic and electric equations is presented. The magnetic equations are solved with the help of finite element method using the magnetic vector potential formulation. To take into account the effects of magnetic saturation we use the Newton-Raphson algorithm. We develop the analysis permitting the coupling of magnetic and electric equations to obtain a difrerential system equations which can be solved with numerical integration. As example we model an iron core coil and the validity of our model is verified by a comparison of the obtained results with an analytical solution and a 2D code calculation. Dans cet article est présenté un modèle 3D qui permet de coupler les équations magnétiques et électriques. Les équations magnétiques sont résolues à l'aide de la méthode des éléments finis en utilisant une formulation en potentiel vecteur magnétique. Dans le modèle proposé les effets de la saturation du circuit magnétique sont pris en compte en utilisant l'algorithme de Newton-Raphson. On montre comment relier les équations magnétiques avec celles du circuit électrique pour aboutir à un système d'équations différentielles que l'on résout avec une intégration numérique. A titre d'exemple on modélise une bobine à noyau ferromagnétique et pour montrer la validité du modèle on compare les résultats obtenus avec une solution analytique et un code de calcul 2D.

Urban Planning by Le Corbusier According to Praxeological Knowledge

NASA Astrophysics Data System (ADS)

Dzwierzynska, Jolanta; Prokopska, Aleksandra

2017-12-01

The city is formed as a mosaic of various elements which affect its attractiveness. These elements range from location attributes, through economic opportunities, to social aspects. Therefore, urbanity and urban planning should be considered in a multi-dimensional context. In the paper we address the problem of urban planning by Le Corbusier according to praxeological and system knowledge. From praxeological point of view an active human being takes his/her choice between various possibilities by preferring one of these possibilities to the others, and by manifesting it by her actions. The same applies to the design process. Due to this fact, the scientific design process can be treated as a systematic rational reconstruction of the designer’s behaviour. Such a reconstruction requires previous reflection on designer’s work, as well as some consideration and design experience, thus know-how knowledge based on methodological knowledge. In the paper several city visions of Le Corbusier, as well as the characteristics and organisation of his design process are analysed. Le Corbusier’s innovative design ideas resulted from industrialisation changes and motorisation accelerating progress, which gave foundation to a new urban array. This array based on strict geometric forms, regularity and repetition determining standard. Thanks to his theories, Le Corbusier established principles of modern city construction and planning. Although some doubts were expressed as to the scale of centralisation of the cities designed by him and his class-based conception, he was awarded that overall welfare of the individual living in a city was the quality of built environment. Therefore, his designed creations were not only functional but they also produced emotions. The analysis of his prolific design activities allows us to state that the organisation of his architectural and urban planning process was very efficient and complex. The city concepts proposed by him were the subject

Ursula LeGuin's Magical World of Earthsea.

ERIC Educational Resources Information Center

Griffin, Jan M.

1996-01-01

Discusses how Ursula LeGuin's Earthsea Trilogy reflects her belief in Taoist philosophy as well as her skill in telling stories of magic and adventure. Notes that the three books can be described as coming-of-age novels in which three separate individuals struggle to become mature, responsible, whole adults. (RS)

A learned artisan debates the system of the world: Le Clerc versus Mallemant de Messange.

PubMed

Rabinovitch, Oded

2017-12-01

Sébastien Le Clerc (1637-1714) was the most renowned engraver of Louis XIV's France. For the history of scientific publishing, however, Le Clerc represents a telling paradox. Even though he followed a traditional route based on classic artisanal training, he also published extensively on scientific topics such as cosmology and mathematics. While contemporary scholarship usually stresses the importance of artisanal writing as a direct expression of artisanal experience and know-how, Le Clerc's publications, and specifically the work on cosmology in his Système du monde (1706-1708), go far beyond this. By reconstructing the debate between Le Clerc and the professor Mallemant de Messange on the authorship of this 'system of the world', this article argues that Le Clerc's involvement in publishing ventures shaped his identity both as an artisan and as a scientific author. Whereas the Scientific Revolution supposedly heralded a change from the world of 'more or less' to the 'world of precision', this article shows how an artisan could be more 'precise' than the learned scholar whose claims he disputed, and points to the importance of the literary field as a useful lens for observing the careers of early modern scientific practitioners.

Le syndrome d’Usher: à propos d’une observation

PubMed Central

Daoudi, Chama; boutimzine, Noureddine; Haouzi, Samia El; Lezrek, Omar; Tachfouti, Samira; Lezrek, Mounir; Laghmari, Mina; Daoudi, Rajae

2017-01-01

Résumé Le syndrome d'Usher est une maladie génétique comportant une double atteinte sensorielle (auditive et visuelle) appelée surdicécité. Nous rapportons l'observation d'un patient de 50 ans, issue d'un mariage consanguin présentant une surdité congénitale avec une fonction vestibulaire normale et une rétinopathie pigmentaire responsable d'une baisse bilatérale de l'acuité visuelle apparue vers l'âge de 16 ans. Cette association compose le type 2 du syndrome d'Usher, affection rare de transmission autosomique récessive. La chirurgie de la cataracte a permis une amélioration de l'acuité visuelle chez ce patient. PMID:28979619

Ensemble des troubles causés par l'alcoolisation fœtale : lignes directrices canadiennes concernant le diagnostic

PubMed Central

Chudley, Albert E.; Conry, Julianne; Cook, Jocelynn L.; Loock, Christine; Rosales, Ted; LeBlanc, Nicole

2005-01-01

Résumé LE DIAGNOSTIC DE L'ENSEMBLE DES TROUBLES CAUSÉS PAR L'ALCOOLISATION FÉTALE (ETCAF) est complexe et l'élaboration de lignes directrices concernant le diagnostic est justifiée. Un sous-comité du Comité consultatif national de l'Agence de santé publique du Canada sur l'Ensemble des troubles causés par l'alcoolisation fœtale a examiné, analysé et intégré les méthodes de diagnostic actuelles afin de parvenir à une méthode de diagnostic normalisée faisant le consensus au Canada. L'objet du présent document est d'examiner et de clarifier l'utilisation des systèmes de diagnostic actuels et de formuler des recommandations quant à leur application pour le diagnostic des déficiences liées à l'ETCAF chez des individus de tous les âges. Les lignes directrices sont fondées sur un vaste consensus de praticiens et d'autres intervenants spécialisés dans le domaine. Ces lignes directrices ont été organisées en sept catégories, soit le dépistage et l'orientation vers les spécialistes, l'examen physique et le diagnostic différentiel, l'évaluation du comportement neurologique, le traitement et le suivi, les antécédents de consommation d'alcool de la mère pendant la grossesse, les critères du diagnostic pour le syndrome d'alcoolisation fœtale (SAF), SAF partiel et troubles neurologiques du développement liés à l'alcool, l'harmonisation de l'Institute of Medicine (IOM) et des approches du Code diagnostique à 4 chiffres. Le diagnostic exige une évaluation complète des antécédents, ainsi qu'un examen physique et du comportement neurologique, tout en recourant à une approche multidisciplinaire. Les présentes lignes directrices pour le diagnostic du syndrome d'alcoolisation fœtale et des déficiences qui y sont associées sont les premières à avoir été élaborées au Canada et elles sont fondées sur la consultation d'un grand éventail de spécialistes du diagnostic.

Overexpression of the tomato pollen receptor kinase LePRK1 rewires pollen tube growth to a blebbling mode

USDA-ARS?s Scientific Manuscript database

The tubular growth of a pollen tube cell is crucial for the sexual reproduction of flowering plants. LePRK1 is a pollen-specific and plasma membrane–localized receptor-like kinase from tomato (Solanum lycopersicum). LePRK1 interacts with another receptor, LePRK2, and with KINASE PARTNER PROTEIN (KPP...

COMMITTEES: Quark Matter 2008 Organising and International Advisory Committees

NASA Astrophysics Data System (ADS)

2008-10-01

Organising Committee Madan M Aggarwal (Chandigarh) Jan-e Alam (Kolkata) Convener Arup Bandyopadhyay (Kolkata) Debades Bandyopadhyay (Kolkata) Rahul Basu (Chennai) Rakesh K Bhandari (Kolkata) Anju Bhasin (Jammu) Subhasis Chattopadhyay (Kolkata) Convener Sukalyan Chattopadhyay (Kolkata) Asis Chaudhuri (Kolkata) Premomoy Ghosh (Kolkata) Sanjay Ghosh (Kolkata) Sourendu Gupta (Mumbai) Muhammad Irfan (Aligarh) Durga P Mahapatra (Bhubaneswar) DAmruta Mishra (New Delhi) Ajit K Mohanty (Mumbai) Bedangadas Mohanty (Kolkata) Vaisali Naik (Kolkata) Tapan K Nayak (Kolkata) Convener Sudhir Raniwala (Jaipur) Sourav Sarkar (Kolkata) Bikash Sinha (Kolkata) Chair Dinesh Srivastava (Kolkata) Raghava Varma (Mumbai) Yogendra P Viyogi (Bhubaneswar)Co-chair International Advisory Committee R Aymar,Switzerland Jean Paul Blaizot, France Peter Braun Münzinger, Germany Igor M Dremin, Russia Kari Eskola, Finland Jens Jorgen Gaardhoje,Denmark Rajiv V Gavai, India Hans-Ake Gustaffson, Sweden Hans Gutbrod, Germany Miklos Gyulassy, USA Timothy Hallman, USA Hideki Hamagaki, Japan Tetsuo Hatsuda, Japan Huan-Zhong Huang, USA Barbara Jacak, USA Peter Jenni, Switzerland Taka Kajino, Japan Takeshi Kodama, Brazil T D Lee, USA Peter Levai, Hungary Luciano Maiani, Italy Larry McLerran, USA Berndt Müller, USA Guy Paic, Mexico Sibaji Raha, India Lodovico Riccati, Italy Hans Georg Ritter, USA Helmut Satz, Germany Jurgen Schukraft, Switzerland Yves Schutz, France Edward V Shuryak, USA Johanna Stachel, Germany Horst Stöcker, Germany Itzhak Tserruya, Israel Xin-Nian Wang, USA Bolek Wyslouch, USA Glenn R Young, USA William A Zajc, USA Wen-Long Zhan, China

Mise à jour sur le nouveau vaccin 9-valent pour la prévention du virus du papillome humain

PubMed Central

Yang, David Yi; Bracken, Keyna

2016-01-01

Résumé Objectif Informer les médecins de famille quant à l’efficacité, à l’innocuité, aux effets sur la santé publique et à la rentabilité du vaccin 9-valent contre le virus du papillome humain (VPH). Qualité des données Des articles pertinents publiés dans PubMed jusqu’en mai 2015 ont été examinés et analysés. La plupart des données citées sont de niveau I (essais randomisés et contrôlés et méta-analyses) ou de niveau II (études transversales, cas-témoins et épidémiologiques). Des rapports et recommandations du gouvernement sont aussi cités en référence. Message principal Le vaccin 9-valent contre le VPH, qui offre une protection contre les types 6, 11, 16, 18, 31, 33, 45, 52 et 58 du VPH, est sûr et efficace et réduira encore plus l’incidence des infections à VPH, de même que les cas de cancer lié au VPH. Il peut également protéger indirectement les personnes non immunisées par l’entremise du phénomène d’immunité collective. Un programme d’immunisation efficace peut prévenir la plupart des cancers du col de l’utérus. Les analyses montrent que la rentabilité du vaccin 9-valent chez les femmes est comparable à celle du vaccin quadrivalent original contre le VPH (qui protège contre les types 6, 11, 16 et 18 du VPH) en usage à l’heure actuelle. Toutefois, il faut investiguer plus en profondeur l’utilité d’immuniser les garçons avec le vaccin 9-valent contre le VPH. Conclusion en plus d’être sûr, le vaccin 9-valent protège mieux contre le VPH que le vaccin quadrivalent. Une analyse coûtefficacité en favorise l’emploi, du moins chez les adolescentes. Ainsi, les médecins devraient recommander le vaccin 9-valent à leurs patients plutôt que le vaccin quadrivalent contre le VPH.

Déclenchement du travail à terme par le misoprostol: expérience d'une maternité tunisienne

PubMed Central

Ouerdiane, Nadia; Tlili, Nihel; Othmani, Kaouther; Daaloul, Walid; Masmoudi, Abdelwaheb; Hamouda, Sonia Ben; Bouguerra, Badreddine

2016-01-01

Evaluer l'efficacité et l'innocuité de l'utilisation du misoprostol par voie vaginale pour le déclenchement du travail à terme. Etude prospective réalisée au service de gynécologie obstétrique B de l'hôpital Charles Nicolle de Tunis sur une durée de 4 mois. La population sélectionnée concernait les patientes à terme devant bénéficier d'une maturation cervicale. Le misoprostol à la dose de 50 µg par voie vaginale toutes les 12 h était utilisé. Les paramètres étudiés étaient les anomalies contractiles, les anomalies du RCF, le mode d'accouchement, le délai d'accouchement et l’état néonatal. 44 patientes ont bénéficié d'une maturation cervicale par misoprostol. Le terme moyen était de 40 SA. Le taux de nullipare était de 23/44 (52%). Le taux d'accouchement par voie basse était de 31/44 (70.4%). 84% des patientes ont reçu une seule dose de misoprostol. Les anomalies du RCF ont été notées dans 14/44 (32%). Le taux de liquides méconiaux était de 12/44 (27%). Un score d'Apgar à 5 mn inférieur à 7 était noté chez 7/44 (16%). Un cas de rupture utérine était survenue chez une primipare et ce après une seule prise de misoprostol. Nos résultats sont décevants en raison de la survenue d'une rupture utérine et d'une morbidité néonatale importante. D'autres études prospectives multicentriques restent utiles pour mieux s'assurer de l'efficacité mais surtout de l'innocuité du misoprostol à dose faible pour le déclenchement du travail à terme. PMID:27583092

Not Just Playing Around: The MoLeNET Experience of Using Games Technologies to Support Teaching and Learning

ERIC Educational Resources Information Center

Petley, Rebecca; Attewell, Jill; Savill-Smith, Carol

2011-01-01

MoLeNET is a unique collaborative initiative, currently in its third year, which encourages and enables the introduction of mobile learning in English post 14 education via supported shared-cost projects. Mobile learning in MoLeNET is defined by MoLeNET as "The exploitation of ubiquitous handheld technologies, together with wireless and…

LeCTR2, a CTR1-like protein kinase from tomato, plays a role in ethylene signalling, development and defence

PubMed Central

Lin, Zhefeng; Alexander, Lucy; Hackett, Rachel; Grierson, Don

2008-01-01

Arabidopsis AtCTR1 is a Raf-like protein kinase that interacts with ETR1 and ERS and negatively regulates ethylene responses. In tomato, several CTR1-like proteins could perform this role. We have characterized LeCTR2, which has similarity to AtCTR1 and also to EDR1, a CTR1-like Arabidopsis protein involved in defence and stress responses. Protein–protein interactions between LeCTR2 and six tomato ethylene receptors indicated that LeCTR2 interacts preferentially with the subfamily I ETR1-type ethylene receptors LeETR1 and LeETR2, but not the NR receptor or the subfamily II receptors LeETR4, LeETR5 and LeETR6. The C-terminus of LeCTR2 possesses serine/threonine kinase activity and is capable of auto-phosphorylation and phosphorylation of myelin basic protein in vitro. Overexpression of the LeCTR2 N-terminus in tomato resulted in altered growth habit, including reduced stature, loss of apical dominance, highly branched inflorescences and fruit trusses, indeterminate shoots in place of determinate flowers, and prolific adventitious shoot development from the rachis or rachillae of the leaves. Expression of the ethylene-responsive genes E4 and chitinase B was upregulated in transgenic plants, but ethylene production and the level of mRNA for the ethylene biosynthetic gene ACO1 was unaffected. The leaves and fruit of transgenic plants also displayed enhanced susceptibility to infection by the fungal pathogen Botrytis cinerea, which was associated with much stronger induction of pathogenesis-related genes such as PR1b1 and chitinase B compared with the wild-type. The results suggest that LeCTR2 plays a role in ethylene signalling, development and defence, probably through its interactions with the ETR1-type ethylene receptors of subfamily I. PMID:18346193

EAARL Topography - Jean Lafitte National Historical Park and Preserve 2006

USGS Publications Warehouse

Nayegandhi, Amar; Brock, John C.; Wright, C. Wayne; Segura, Martha; Yates, Xan

2008-01-01

These remotely sensed, geographically referenced elevation measurements of Lidar-derived first surface (FS) and bare earth (BE) topography were produced as a collaborative effort between the U.S. Geological Survey (USGS), Florida Integrated Science Center (FISC), St. Petersburg, FL; the National Park Service (NPS), Gulf Coast Network, Lafayette, LA; and the National Aeronautics and Space Administration (NASA), Wallops Flight Facility, VA. This project provides highly detailed and accurate datasets of the Jean Lafitte National Historical Park and Preserve in Louisiana, acquired on September 22, 2006. The datasets are made available for use as a management tool to research scientists and natural resource managers. An innovative airborne Lidar instrument originally developed at the NASA Wallops Flight Facility, and known as the Experimental Advanced Airborne Research Lidar (EAARL), was used during data acquisition. The EAARL system is a raster-scanning, waveform-resolving, green-wavelength (532-nanometer) Lidar designed to map near-shore bathymetry, topography, and vegetation structure simultaneously. The EAARL sensor suite includes the raster-scanning, water-penetrating full-waveform adaptive Lidar, a down-looking red-green-blue (RGB) digital camera, a high-resolution multi-spectral color infrared (CIR) camera, two precision dual-frequency kinematic carrier-phase GPS receivers, and an integrated miniature digital inertial measurement unit, which provide for submeter georeferencing of each laser sample. The nominal EAARL platform is a twin-engine Cessna 310 aircraft, but the instrument may be deployed on a range of light aircraft. A single pilot, a Lidar operator, and a data analyst constitute the crew for most survey operations. This sensor has the potential to make significant contributions in measuring sub-aerial and submarine coastal topography within cross-environmental surveys. Elevation measurements were collected over the survey area using the EAARL system

Unsupervised classification of lidar-based vegetation structure metrics at Jean Lafitte National Historical Park and Preserve

USGS Publications Warehouse

Kranenburg, Christine J.; Palaseanu-Lovejoy, Monica; Nayegandhi, Amar; Brock, John; Woodman, Robert

2012-01-01

Traditional vegetation maps capture the horizontal distribution of various vegetation properties, for example, type, species and age/senescence, across a landscape. Ecologists have long known, however, that many important forest properties, for example, interior microclimate, carbon capacity, biomass and habitat suitability, are also dependent on the vertical arrangement of branches and leaves within tree canopies. The objective of this study was to use a digital elevation model (DEM) along with tree canopy-structure metrics derived from a lidar survey conducted using the Experimental Advanced Airborne Research Lidar (EAARL) to capture a three-dimensional view of vegetation communities in the Barataria Preserve unit of Jean Lafitte National Historical Park and Preserve, Louisiana. The EAARL instrument is a raster-scanning, full waveform-resolving, small-footprint, green-wavelength (532-nanometer) lidar system designed to map coastal bathymetry, topography and vegetation structure simultaneously. An unsupervised clustering procedure was then applied to the 3-dimensional-based metrics and DEM to produce a vegetation map based on the vertical structure of the park's vegetation, which includes a flotant marsh, scrub-shrub wetland, bottomland hardwood forest, and baldcypress-tupelo swamp forest. This study was completed in collaboration with the National Park Service Inventory and Monitoring Program's Gulf Coast Network. The methods presented herein are intended to be used as part of a cost-effective monitoring tool to capture change in park resources.

Le niobate de lithium a haute temperature pour les applications ultrasons =

NASA Astrophysics Data System (ADS)

De Castilla, Hector

L'objectif de ce travail de maitrise en sciences appliquees est de trouver puis etudier un materiau piezoelectrique qui est potentiellement utilisable dans les transducteurs ultrasons a haute temperature. En effet, ces derniers sont actuellement limites a des temperatures de fonctionnement en dessous de 300°C a cause de l'element piezoelectrique qui les compose. Palier a cette limitation permettrait des controles non destructifs par ultrasons a haute temperature. Avec de bonnes proprietes electromecaniques et une temperature de Curie elevee (1200°C), le niobate de lithium (LiNbO 3) est un bon candidat. Mais certaines etudes affirment que des processus chimiques tels que l'apparition de conductivite ionique ou l'emergence d'une nouvelle phase ne permettent pas son utilisation dans les transducteurs ultrasons au-dessus de 600°C. Cependant, d'autres etudes plus recentes ont montre qu'il pouvait generer des ultrasons jusqu'a 1000°C et qu'aucune conductivite n'etait visible. Une hypothese a donc emerge : une conductivite ionique est presente dans le niobate de lithium a haute temperature (>500°C) mais elle n'affecte que faiblement ses proprietes a hautes frequences (>100 kHz). Une caracterisation du niobate de lithium a haute temperature est donc necessaire afin de verifier cette hypothese. Pour cela, la methode par resonance a ete employee. Elle permet une caracterisation de la plupart des coefficients electromecaniques avec une simple spectroscopie d'impedance electrochimique et un modele reliant de facon explicite les proprietes au spectre d'impedance. Il s'agit de trouver les coefficients du modele permettant de superposer au mieux le modele avec les mesures experimentales. Un banc experimental a ete realise permettant de controler la temperature des echantillons et de mesurer leur impedance electrochimique. Malheureusement, les modeles actuellement utilises pour la methode par resonance sont imprecis en presence de couplages entre les modes de vibration. Cela

MODeLeR: A Virtual Constructivist Learning Environment and Methodology for Object-Oriented Design

ERIC Educational Resources Information Center

Coffey, John W.; Koonce, Robert

2008-01-01

This article contains a description of the organization and method of use of an active learning environment named MODeLeR, (Multimedia Object Design Learning Resource), a tool designed to facilitate the learning of concepts pertaining to object modeling with the Unified Modeling Language (UML). MODeLeR was created to provide an authentic,…

Histoire d’un itinéraire épidémiologique entre le Burkina Faso et la Côte d’Ivoire : le cas des foyers de maladie du sommeil de Koudougou

PubMed Central

Kiendrébéogo, D.; Kambiré, R.; Jamonneau, V.; Lingué, K.; Solano, P.; Courtin, F.

2012-01-01

Dans la première moitié du XXème siècle, alors que la Haute-Volta (actuel Burkina Faso) subissait une terrible épidémie de maladie du sommeil, l’administration coloniale française a orchestré des déplacements massifs de populations de la Haute-Volta vers la Côte d’Ivoire, pour exploiter le territoire. Cela a conduit à la mise en place de villages de colonisation Mossi en zone forestière ivoirienne, comme ceux de Koudougou, issus de l’une des régions les plus peuplées de Haute-Volta, mais aussi l’une des plus touchées par la maladie du sommeil. Depuis 2000, au Burkina Faso, c’est dans le district sanitaire de Koudougou que sont dépistés passivement le plus grand nombre de trypanosomés en provenance de Côte d’Ivoire. Qui sont-ils ? Où habitent-ils au Burkina Faso ? D’où viennent-ils de Côte d’Ivoire ? Après avoir retracé l’histoire épidémiologique des villages de Koudougou au Burkina Faso et en Côte d’Ivoire, nous avons recherché les trypanosomés dépistés passivement depuis 2000 dans le district sanitaire de Koudougou au Burkina Faso. Au total, dix trypanosomés ont été enquêtés. Le processus de propagation de la maladie du sommeil dans l’espace ivoiro-burkinabé a été mis en évidence et des zones à risque de la maladie identifiées dans ce même espace. PMID:23193525

National Dam Inspection Program. Lake Jean Dam. (NDI I.D. Number PA-00570 PennDER I.D. Number 40-16) Susquehanna River Basin, Branch of Kitchen Creek, Luzerne County, Pennsylvania. Phase I Inspection Report,

DTIC Science & Technology

1980-07-01

ANALYSES APPENDIX E - FIGURES APPENDIX F - GEOLOGY 1 v~i I LI PHASE I INSPECTION REPORT NATIONAL DAM INSPECTION PROGRAM LAKE JEAN DAM NDI# PA-00570...Red Rock, Pennsylvania, U.S.G.S. 7.5 minute topographic quadrangle (see Figure 1, Appendix E ). The coordinates of the dam are N41* 21.1’ and W76 0...3.1. e ). e . Ownership. Commonwealth of Pennsylvania Office of Resources Management Department of Environmental Resources P.O. Box 1467 Harrisburg

Le TERS, ou comment obtenir une signature chimique à l'échelle nanométrique

NASA Astrophysics Data System (ADS)

Hsia, Patrick; Chaigneau, Marc

2018-02-01

Le TERS pour tip enhanced raman scattering, est une technique de pointe (dans tous les sens du terme) basée sur l'amplification du signal Raman relative à la résonance de plasmons de surface. Cette technique non-destructive, qui ne nécessite pas de marquage particulier, permet de caractériser un échantillon à l'échelle nanométrique. Le TERS s'impose aujourd'hui pour sonder les propriétés physico-chimiques des nanomatériaux et participer ainsi au développement de nouvelles applications dans le domaine des nanotechnologies.

Le don après un décès d'origine cardiocirculatoire au Canada

PubMed Central

Shemie, Sam D.; Baker, Andrew J.; Knoll, Greg; Wall, William; Rocker, Graeme; Howes, Daniel; Davidson, Janet; Pagliarello, Joe; Chambers-Evans, Jane; Cockfield, Sandra; Farrell, Catherine; Glannon, Walter; Gourlay, William; Grant, David; Langevin, Stéphan; Wheelock, Brian; Young, Kimberly; Dossetor, John

2006-01-01

Résumé Ces recommandations sont le fruit d'un processus multidisciplinaire national ayant duré un an et visant à déterminer si et comment l'on pourrait procéder au don d'organes après un décès d'origine cardiocirculatoire («don après le décès cardiocirculatoire», ou DDC) au Canada. Le forum national organisé en février 2005 a permis aux participants de discuter et d'élaborer des recommandations sur les principes, interventions et pratiques se rapportant au DDC. Les aspects éthiques et juridiques ont été abordés dans les discussions. À la fin du Forum, la majorité des participants ont été favorables à l'implantation de programmes de DDC au Canada. Les participants du Forum ont également convenu qu'il fallait formuler et prôner des valeurs fondamentales pour orienter l'élaboration de programmes et de protocoles basés sur le cadre médical, éthique et juridique établi lors de cette réunion. Même si la possibilité d'un don d'organes et de tissus doit faire partie intégrante des soins de fin de vie, il faut insister sur le fait que le devoir de diligence envers les patients mourants et leurs familles doit demeurer la priorité des équipes soignantes. La complexité et les répercussions profondes du décès sont reconnues et doivent être respectées, de même que les différences personnelles, ethnoculturelles et religieuses face à la mort et au don d'organes. Les décisions d'arrêter le traitement de maintien des fonctions vitales, la prise en charge des derniers moments de la vie et le diagnostic de décès selon des critères cardiocirculatoires doivent être distincts et indépendants des processus de don et transplantation. Ce rapport contient des recommandations destinées aux gestionnaires de program, aux autorités sanitaires régionales et aux instances appelés à élaborer les protocoles de DDC. Les programmes doivent être conçus en fonction des éléments suivants : direction et planification locales, éducation et

Characterization of LeMir, a Root-Knot Nematode-Induced Gene in Tomato with an Encoded Product Secreted from the Root1

PubMed Central

Brenner, Eric D.; Lambert, Kris N.; Kaloshian, Isgouhi; Williamson, Valerie M.

1998-01-01

A tomato gene that is induced early after infection of tomato (Lycopersicon esculentum Mill.) with root-knot nematodes (Meloidogyne javanica) encodes a protein with 54% amino acid identity to miraculin, a flavorless protein that causes sour substances to be perceived as sweet. This gene was therefore named LeMir (L. esculentum miraculin). Sequence similarity places the encoded protein in the soybean trypsin-inhibitor family (Kunitz). LeMir mRNA is found in root, hypocotyl, and flower tissues, with the highest expression in the root. Rapid induction of expression upon nematode infection is localized to root tips. In situ hybridization shows that LeMir is expressed constitutively in the root-cap and root-tip epidermis. The LeMir protein product (LeMir) was produced in the yeast Pichia pastoris for generation of antibodies. Western-blot analysis showed that LeMir expression is up-regulated by nematode infection and by wounding. LeMir is also expressed in tomato callus tissue. Immunoprint analysis revealed that LeMir is expressed throughout the seedling root, but that levels are highest at the root/shoot junction. Analysis of seedling root exudates revealed that LeMir is secreted from the root into the surrounding environment, suggesting that it may interact with soil-borne microorganisms. PMID:9733543

Upscaling mixing in porous media from an experimental quantification of pore scale Lagrangian deformation statistics

NASA Astrophysics Data System (ADS)

Turuban, R.; Jimenez-Martinez, J.; De Anna, P.; Tabuteau, H.; Meheust, Y.; Le Borgne, T.

2014-12-01

As dissolved chemical elements are transported in the subsurface, their mixing with other compounds and potential reactivity depends on the creation of local scale chemical gradients, which ultimately drive diffusive mass transfer and reaction. The distribution of concentration gradients is in turn shaped by the spatial gradients of flow velocity arising from the random distribution of solid grains. We present an experimental investigation of the relationship between the microscale flow stretching properties and the effective large scale mixing dynamics in porous media. We use a flow cell that models a horizontal quasi two-dimensional (2D) porous medium, the grains of which are cylinders randomly positioned between two glass plates [de Anna et al. 2013]. In this setup, we perform both non diffusive and diffusive transport tests, by injecting respectively microsphere solid tracers and a fluorescent dye. While the dye front propagates through the medium, it undergoes in time a kinematic stretching that is controlled by the flow heterogeneity, as it encounters stagnation zones and high velocity channels between the grains. The spatial distribution of the dye can then be described as a set of stretched lamellae whose rate of diffusive smoothing is locally enhanced by kinematic stretching [Le Borgne et al., 2013]. We show that this representation allows predicting the temporal evolution of the mixing rate and the probability distribution of concentration gradients for a range of Peclet numbers. This upscaling framework hence provides a quantification of the dynamics of effective mixing from the microscale Lagrangian velocity statistics. References:[1] P. de Anna, J. Jimenez-Martinez, H. Tabuteau, R. Turuban, T. Le Borgne, M. Derrien,and Yves Méheust, Mixing and reaction kinetics in porous media : an experimental pore scale quantification, Environ. Sci. Technol. 48, 508-516, 2014. [2] Le Borgne, T., M. Dentz, E. Villermaux, Stretching, coalescence and mixing in porous

Stratigraphy and Geochemistry of a Fond St. Jean Cinder Cone, Dominica

NASA Astrophysics Data System (ADS)

Isenburg, T.; Frey, H. M.; Waters, L. E.; Dunn, S.; Manon, M. R. F.

2017-12-01

Current geologic maps of Dominica generally classify the south-eastern portion of the island surrounding the Foundland stratovolcano as "mafic breccias and thin lava flows of Foundland center" (Smith et al. 2013). A detailed survey of the stratigraphy of a road cut at Fond St. Jean provides evidence for a mafic cinder cone on the flanks of Foundland. The 39 m thick stratigraphic sequence, dipping 60˚ north, includes a basal unit of scoria overlain by a meter of basaltic breccia and repeating layers of massive and rubbly flows, which range from 1 to 10 m in thickness. These flows transition into an additional, 2 m thick scoria deposit capped by a meter of massive basalt, which sits beneath another 3-4 m scoria deposit. Another layer of massive flow then transitions to three units of alternating air fall and ash lenses. Air fall units are 0.5 m in thickness but pinch and swell regularly, and ash lenses are roughly 10 cm thick. All units contain plagioclase + olivine + clinopyroxene + orthopyroxene + titanomagnetite. Though the phase assemblage is consistent between basaltic units, different crystal morphologies serve to define individual massive flows. Variations in the texture of materials deposited by the cinder cone provides evidence for cyclic explosive and effusive episodes. Massive samples at the bottom of the stratigraphic section contain abundant, large olivine and tabular, elongate plagioclase. Plagioclase compositions between individual stratigraphic units span a similar range in composition. Massive flows throughout the column contain similar, weakly zoned plagioclase cores (An84-94) with 10-30 µm sodic rims (An58-78; most rims are 68). Plagioclase microlites (long axes ≤100µm) span a wide range of compositions (An50-90). Three different air fall units contain plagioclase rims ranging in composition from An58-86 and cores ranging from An84-92, with the exception of a single core that has a composition of An61. Olivine in most units ranges in

Deriving fractional rate of degradation of logistic-exponential (LE) model to evaluate early in vitro fermentation.

PubMed

Wang, M; Sun, X Z; Tang, S X; Tan, Z L; Pacheco, D

2013-06-01

Water-soluble components of feedstuffs are mainly utilized during the early phase of microbial fermentation, which could be deemed an important determinant of gas production behavior in vitro. Many studies proposed that the fractional rate of degradation (FRD) estimated by fitting gas production curves to mathematical models might be used to characterize the early incubation for in vitro systems. In this study, the mathematical concept of FRD was developed on the basis of the Logistic-Exponential (LE) model, with initial gas volume being zero (LE0). The FRD of the LE0 model exhibits a continuous increase from initial (FRD 0) toward final asymptotic value (FRD F) with longer incubation time. The relationships between the FRD and gas production at incubation times 2, 4, 6, 8, 12 and 24 h were compared for four models, in addition to LE0, Generalization of the Mitscherlich (GM), c th order Michaelis-Menten (MM) and Exponential with a discrete LAG (EXPLAG). A total of 94 in vitro gas curves from four subsets with a wide range of feedstuffs from different laboratories and incubation periods were used for model testing. Results indicated that compared with the GM, MM and EXPLAG models, the FRD of LE0 model consistently had stronger correlations with gas production across the four subsets, especially at incubation times 2, 4, 6, 8 and 12 h. Thus, the LE0 model was deemed to provide a better representation of the early fermentation rates. Furthermore, the FRD 0 also exhibited strong correlations (P < 0.05) with gas production at early incubation times 2, 4, 6 and 8 h across all four subsets. In summary, the FRD of LE0 model provides an alternative to quantify the rate of early stage incubation, and its initial value could be an important starting parameter of rate.

Contrôle du marché informel à l’heure de la mondialisation des échanges. Le cas des antirétroviraux au Chili

PubMed Central

Brousselle, Astrid; Morales, Cristián

2013-01-01

Résumé Les nouveaux médicaments pour le VIH/sida ont créé des besoins d’accessibilité aux traitements que les gouvernements n’ont pas toujours réussi à couvrir. Il en résulte l’émergence d’un marché informel des ARV. Par l’analyse de la situation au Chili, nous traitons des différents créneaux d’approvisionnement, des conséquences de l’existence d’un tel marché, ainsi que des moyens envisageables pour réduire les effets indésirables. Les aspects tant microéconomiques que macroéconomiques concernant le marché et l’accessibilité aux médicaments sont abordés. PMID:23997580

Dynamique des ressources naturelles dans le Parc national de Manda: Cartographie et analyse pour le Développement durable

NASA Astrophysics Data System (ADS)

Ballah Solkam, Rosalie; Médard, Ndoutorlengar

2018-05-01

Au Tchad, le réseau d'aires protégées couvre près de 10,2% de la surface du pays et reste globalement représentatif de toute la diversité des écosystèmes de la région. Cependant, ce réseau n'est pas constitué d'écosystèmes intacts car de nombreuses altérations y ont été apportés (certaines espèces sont déjà au seuil critique d'extinction (Addax, gazelle dama, lamantin), voire ont disparu (Rhinocéros noir et blanc, Oryx)) surtout dans les parcs nationaux. Ce qui nous amène à nous interroger sur la dynamique des ressources naturelles et le degré de conservation du parc national de Manda? Une évaluation de la diversité biologique et des ressources hydrographiques de 1951 à 1999 sur la base de la bibliographie existante, de la carte topographique de 1956, des images satellitaires Landsat 5 et 7 TM et ETM+ de 2 périodes (1986, 1999), complétée par des interviews semi-structurés et des transects sur le terrain, permettra de mieux appréhender la dynamique des ressources et les actions de conservation de la biodiversité réalisées à cet effet. Les résultats montrent une dynamique progressive de la faune de 1951 à 1970, puis une dynamique régressive de 1970 à 1989. Après cette tumultueuse période, un repeuplement du parc s'opère de 1989 à 2002. Par contre, la flore est relativement bien conservée avec quelques cours d'eau, des mares, champs et plantations. Et cela grâce aux multiples projets de conservation de la biodiversité. La promotion de l'écotourisme serait une alternative au développement durable de ce parc.

STIL, a peculiar molecule from styles, specifically dephosphorylates the pollen receptor kinase LePRK2 and stimulates pollen tube growth in vitro

USDA-ARS?s Scientific Manuscript database

BACKGROUND: LePRK1 and LePRK2 are two pollen receptor kinases localized to the plasma membrane, where they are present in a high molecular weight complex (LePRK complex). LePRK2 is phosphorylated in mature and germinated pollen, but is dephosphorylated when pollen membranes are incubated with tomato...

Genome Sequence of Novosphingobium lindaniclasticum LE124T, Isolated from a Hexachlorocyclohexane Dumpsite

PubMed Central

Saxena, Anjali; Nayyar, Namita; Sangwan, Naseer; Kumari, Rashmi; Khurana, J. P.

2013-01-01

Novosphingobium lindaniclasticum LE124T is a hexachlorocyclohexane (HCH)-degrading bacterium isolated from a high-dosage-point HCH dumpsite (450 mg HCH/g soil) located in Lucknow, India (27°00′N and 81°09′E). Here, we present the annotated draft genome sequence of strain LE124T, which has an estimated size of 4.86 Mb and is comprised of 4,566 coding sequences. PMID:24029761

Le traumatisme du colon: l'expérience du CHU Hassan II de Fès

PubMed Central

Benjelloun, El Bachir; Hafid, Hasnai; Karim, Ibnmajdoub; Ousadden, Abdelmalek; Mazaz, Khalid; Taleb, Kahlid Ait

2012-01-01

Introduction Les traumatismes du colon sont associés à un risque majeur de complications septiques et de mortalité. Le but de notre étude est d’évaluer les circonstances, la prise en charge, le suivi et les facteurs pronostic de morbidité postopératoire des malades victimes d'un traumatisme colique. Méthodes Il s'agit d'une étude rétrospective sur une série de 49 patients opérés pour des plaies coliques aux services de chirurgie viscérale du CHU HASSAN II de Fès sur une période de 8 ans de juillet 2003 à juillet 2011. Résultats L’âge moyen de nos patients était de 25ans (16-70) avec une nette prédominance masculine (93.8%). Les plaies coliques secondaires à un traumatisme par arme blanche représentent 85% des cas (42 patients), suivi par les plaies iatrogènes au cours d'une coloscopie chez 6 patients (13%), puis les contusions abdominales chez 1 patient (2%). Les parties du cadre colique les plus touchées étaient le colon transverse chez 19 patients (38%) et le colon descendant chez 12 patients (24, 5%). Le colon sigmoïde était le segment le plus touché au cours d'une coloscopie4/6. Quarante-deux patients (85%) ont eu une suture primaire des plaies coliques, six patients (13%) une diversion fécale et un patient (2%) une résection-anastomose. Deux patients (4%) sont décédés suite à un choc septique. La morbidité globale était de 38,7% dominé essentiellement par l'infection de la paroi chez 14 patients et une péritonite post opératoire chez 3 patients. L'analyse univarié a montré une différence significatif en terme d'infection de la paroi entre le groupe colostomie versus suture simple (50% vs 20,9% p<0,05). L'atteinte du colon gauche et la réalisation d'une colostomie sont associés à un risque plus élevés de complications postopératoires. Conclusion La suture primaire peut être effectuée avec un faible taux de complications postopératoire chez la majorité des patients suite à un traumatisme du colon. PMID

LeMYC2 acts as a negative regulator of blue light mediated photomorphogenic growth, and promotes the growth of adult tomato plants

PubMed Central

2014-01-01

Background Arabidopsis ZBF1/MYC2bHLH transcription factor is a repressor of photomorphogenesis, and acts as a point of cross talk in light, abscisic acid (ABA) and jasmonic acid (JA) signaling pathways. MYC2 also functions as a positive regulator of lateral root development and flowering time under long day conditions. However, the function of MYC2 in growth and development remains unknown in crop plants. Results Here, we report the functional analyses of LeMYC2 in tomato (Lycopersicon esculentum). The amino acid sequence of LeMYC2 showed extensive homology with Arabidopsis MYC2, containing the conserved bHLH domain. To study the function of LeMYC2 in tomato, overexpression and RNA interference (RNAi) LeMYC2 tomato transgenic plants were generated. Examination of seedling morphology, physiological responses and light regulated gene expression has revealed that LeMYC2 works as a negative regulator of blue light mediated photomorphogenesis. Furthermore, LeMYC2 specifically binds to the G-box of LeRBCS-3A promoter. Overexpression of LeMYC2 has led to increased root length with more number of lateral roots. The tomato plants overexpressing LeMYC2 have reduced internode distance with more branches, and display the opposite morphology to RNAi transgenic lines. Furthermore, this study shows that LeMYC2 promotes ABA and JA responsiveness. Conclusions Collectively, this study highlights that working in light, ABA and JA signaling pathways LeMYC2 works as an important regulator for growth and development in tomato plants. PMID:24483714

Conception et calibration d'un sonoreacteur pour l'oxydation de la cellulose par le systeme TEMPO/NaOCl/NaBr

NASA Astrophysics Data System (ADS)

Paquin, Michel

Avec le contexte economique actuel dans le domaine des pates et papiers au Canada, l'industrie se doit de diversifier ses produits mis en marche. La fermeture de plus de 20 usines depuis 2005, une baisse du PIB de l'industrie de 1,4 milliard CAD entre 1999--2008, une baisse de la demande de 2,4 %, une diminution du prix de la pate de 20,9 % depuis juillet 2009. La delocalisation du secteur vers l'Asie et l'hemisphere sud sont autant de raisons pour laquelle l'industrie se doit d'etre a l'avant plan de nouvelle technologie a base de fibre de bois. Pour augmenter leur rentabilite, l'industrie se doit de diversifier ses produits dans d'autres secteurs que le simple fabricant de papier impression-ecriture. Sa diversification passe par l'elaboration de nouveaux papiers a valeur ajoutee (papier conducteur, papier bioactif, etc.), par l'utilisation de la biomasse forestiere pour la production d'energie, par l'utilisation de la biomasse forestiere pour l'elaboration d'une plateforme de chimie verte, par l'utilisation de la lignine pour le developpement de polymeres et par l'utilisation de la fibre cellulosique pour la fabrication de nanomateriaux. La fabrication de nanofibrille de cellulose peut devenir un des produits qui servira a diversifier la production des usines de pates et papiers. Les nanofibrilles de cellulose possedent des proprietes mecaniques et chimiques exceptionnelles. Les nanofibrilles de cellulose sont fabriquees a partir d'une oxydation selective de la pate kraft de feuillu avec le systeme TEMPO-NaOCl-NaBr. L'oxydation selective de l'alcool primaire en C6 du monomere de glucose sous forme de carboxylates engendre une modification chimique de la cellulose qui accroit l'hydrophilicite des fibrilles. Suite a cette oxydation, nous devons effectuer une desintegration mecanique de la fibre kraft de feuillu oxydee pour separer les fibrilles. Le processus d'oxydation de la fibre par le systeme TEMPO-NaOCl-NaBr et sa defibrillation par la suite engendre une

Programmable lithography engine (ProLE) grid-type supercomputer and its applications

NASA Astrophysics Data System (ADS)

Petersen, John S.; Maslow, Mark J.; Gerold, David J.; Greenway, Robert T.

2003-06-01

There are many variables that can affect lithographic dependent device yield. Because of this, it is not enough to make optical proximity corrections (OPC) based on the mask type, wavelength, lens, illumination-type and coherence. Resist chemistry and physics along with substrate, exposure, and all post-exposure processing must be considered too. Only a holistic approach to finding imaging solutions will accelerate yield and maximize performance. Since experiments are too costly in both time and money, accomplishing this takes massive amounts of accurate simulation capability. Our solution is to create a workbench that has a set of advanced user applications that utilize best-in-class simulator engines for solving litho-related DFM problems using distributive computing. Our product, ProLE (Programmable Lithography Engine), is an integrated system that combines Petersen Advanced Lithography Inc."s (PAL"s) proprietary applications and cluster management software wrapped around commercial software engines, along with optional commercial hardware and software. It uses the most rigorous lithography simulation engines to solve deep sub-wavelength imaging problems accurately and at speeds that are several orders of magnitude faster than current methods. Specifically, ProLE uses full vector thin-mask aerial image models or when needed, full across source 3D electromagnetic field simulation to make accurate aerial image predictions along with calibrated resist models;. The ProLE workstation from Petersen Advanced Lithography, Inc., is the first commercial product that makes it possible to do these intensive calculations at a fraction of a time previously available thus significantly reducing time to market for advance technology devices. In this work, ProLE is introduced, through model comparison to show why vector imaging and rigorous resist models work better than other less rigorous models, then some applications of that use our distributive computing solution are shown

78 FR 16565 - Culturally Significant Objects Imported for Exhibition Determinations: “Le Corbusier: An Atlas of...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-15

... DEPARTMENT OF STATE [Public Notice 8239] Culturally Significant Objects Imported for Exhibition Determinations: ``Le Corbusier: An Atlas of Modern Landscapes'' SUMMARY: Notice is hereby given of the following... ``Le Corbusier: An Atlas of Modern Landscapes,'' imported from abroad for temporary exhibition within...

Extended Le Chatelier's formula for carbon dioxide dilution effect on flammability limits.

PubMed

Kondo, Shigeo; Takizawa, Kenji; Takahashi, Akifumi; Tokuhashi, Kazuaki

2006-11-02

Carbon dioxide dilution effect on the flammability limits was measured for various flammable gases. The obtained values were analyzed using the extended Le Chatelier's formula developed in a previous study. As a result, it has been found that the flammability limits of methane, propane, propylene, methyl formate, and 1,1-difluoroethane are adequately explained by the extended Le Chatelier's formula using a common set of parameter values. Ethylene, dimethyl ether, and ammonia behave differently from these compounds. The present result is very consistent with what was obtained in the case of nitrogen dilution.

SCaLeM: A Framework for Characterizing and Analyzing Execution Models

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chavarría-Miranda, Daniel; Manzano Franco, Joseph B.; Krishnamoorthy, Sriram

2014-10-13

As scalable parallel systems evolve towards more complex nodes with many-core architectures and larger trans-petascale & upcoming exascale deployments, there is a need to understand, characterize and quantify the underlying execution models being used on such systems. Execution models are a conceptual layer between applications & algorithms and the underlying parallel hardware and systems software on which those applications run. This paper presents the SCaLeM (Synchronization, Concurrency, Locality, Memory) framework for characterizing and execution models. SCaLeM consists of three basic elements: attributes, compositions and mapping of these compositions to abstract parallel systems. The fundamental Synchronization, Concurrency, Locality and Memory attributesmore » are used to characterize each execution model, while the combinations of those attributes in the form of compositions are used to describe the primitive operations of the execution model. The mapping of the execution model’s primitive operations described by compositions, to an underlying abstract parallel system can be evaluated quantitatively to determine its effectiveness. Finally, SCaLeM also enables the representation and analysis of applications in terms of execution models, for the purpose of evaluating the effectiveness of such mapping.« less

"Panic": the impact of Le Bon's crowd psychology on U.S. military thought.

PubMed

Bendersky, Joseph W

2007-01-01

The controversial crowd psychology of Gustave Le Bon has been both praised as an incisive contribution to social theory and also condemned as a doctrine of irrationality and mass manipulation associated with fascism. New archival documentation now demonstrates that Le Bon exercised significant influence on U.S. military thinking and practice through World War II. Army writings and officer training on morale, leadership, and battlefield psychology rested substantially on his theory of crowds, particularly regarding races and panic. Le Bon's racial psychology took on additional importance when the African-American 92 nd Infantry Division panicked during combat in Italy. This new evidence offers an excellent case study of the direct and enduring impact of a peculiar type of social psychology on the institutional culture of the army from the classrooms at the Army War College to the battlefield itself. (c) 2007 Wiley Periodicals, Inc.

Syndrome métabolique chez les patients hypertendus dans le service cardiologie du CHU Yalgado Ouedraogo de Ouagadougou, Burkina Faso

PubMed Central

Millogo, Georges Rosario Christian; Samandoulougou, André; Yaméogo, Nobila Valentin; Yaméogo, Aristide Relwendé; Kologo, Koudougou Jonas; Toguyeni, Jean Yves; Zabsonré, Patrice

2014-01-01

Introduction Le syndrome métabolique constitue de nos jours un véritable problème de santé publique. Le syndrome métabolique est le moteur d'une double épidémie mondiale de diabète type II et de maladies cardiovasculaires. L'objectif de notre étude est de décrire les aspects épidémiologiques, cliniques, para cliniques et évolutifs chez les hypertendus dans le service de Cardiologie du CHU Yalgado Ouédraogo. Méthodes Il s'agissait d'une étude rétrospective sur une période de deux ans dans le service de cardiologie chez les patients hypertendus ayant un syndrome métabolique. Résultats La fréquence du syndrome métabolique était de 17,5% des patients hypertendus. Le sex ratio était de 1,2. L’âge moyen des patients étaient de 56,1 ±10,7 ans. Les patients connus hypertendus étaient de 92,1% avec une durée moyenne d’évolution de l'HTA qui était de 8,7 ± 5,9 ans. Le suivi était irrégulier dans 60% cas et une rupture du traitement dans 37,1% des cas. La dyslipidémie était notée dans 84,2% des cas et le diabète dans 60,5% des cas. La PAS moyenne était de 184,3 ± 47,3 mmHg et la PAD moyenne était de 110,7 ± 27,7 mmHg. L'HTA était sévère dans 63,2% des cas. La glycémie moyenne était de 8,3 ± 4,3 mmol/L, le LDL cholestérol moyen était de 3,5 ± 1,0 mmol/L et le taux des triglycérides moyen était de 1,6 ± 1,1 mmol/L. L'HVG électrique était notée chez 76,3% des patients et échographique dans 58,8% des cas. Les atteintes viscérales étaient neurologique dans 44,5%, rénale dans 55,3% et cardiaque dans 31,2% des cas. Le nombre moyen d'antihypertenseurs était de 3,0 ± 1,0 et 76,3% ont reçu au moins une trithérapie antihypertensive. Le taux de mortalité était de 5,3%. Conclusion Le syndrome métabolique est une pathologie qui pose la problématique de la définition qui n'est pas consensuelle d'une part et d'autre part du contrôle de ses éléments constitutifs surtout l'HTA. PMID:25883718

Le HELLP syndrome: à propos de 61 cas et revue de la littérature

PubMed Central

Mamouni, Nisrine; Bougern, Hakima; Derkaoui, Ali; Bendahou, Karima; Fakir, Samira; Bouchikhi, Chehrazad; Chaara, Hikmat; Banani, Abdelaziz; Abdelilah, Moulay Melhouf

2012-01-01

Introduction L’objectif de ce travail etait d’étudier et comparer les paramètres épidémiologiques, cliniques, paracliniques et évolutifs des patientes présentant un HELLP syndrome complet et incomplet. (Hemolysis, Elevated Liver enzymes, Low Platelets count). Méthodes Une enquête rétrospective sur la période du 1er janvier 2005 au 31octobre 2008 et incluant tous les cas de HELLP syndrome colligés au service de Gynécologie obstétrique du CHU HASSAN II de Fès, incluant toutes les patientes ayant présenté un HELLP syndrome. Les patientes ont été classées en deux groupes en fonction de la forme du HELLP syndrome (complète ou incomplète). Résultats 61 patientes ont été incluses, dont 29 ont présenté un HELLP syndrome complet (groupe 1) et 32 ont présenté une forme incomplète de ce syndrome (groupe 2). La moyenne d’âge était de 29,7 ± 7 ans pour le groupe 1 et de 28,5 ± 7 ans pour le groupe 2.La gestité moyenne était de 2,8, Pour le groupe 1et de 2,5 pour le groupe 2.Les complications maternelles ont été notées chez 68,9% des patientes avec HELLP complet et 53% avec HELLP incomplet. On a recensés trois cas de décès maternel dans le groupe HELLP complet contre aucun cas dans la forme incomplète. Conclusion D’après les résultats de notre étude, le HELLP complet n’expose pas les patientes à un risque plus élevé de complications maternelles que dans la forme incomplète. PMID:22514764

Snow in Castile-León: trends and variability

NASA Astrophysics Data System (ADS)

Merino, A.; Campos, L.; López, L.; García-Ortega, E.; Sánchez, J. L.; Marcos, J. L.; Guerrero-Higueras, A. M.

2012-04-01

The location of Castile and León, inside the Iberian Peninsula, in the Northwestern quadrant, determines, in large measure, the climatic conditions of its territory, granting it very characteristic traits, mostly in the mountainous areas. It is important to note that during a large part of the year, the region is under the influence of Jet Stream, and thus, gives way to very diverse dynamic situations, which turn into different and heterogeneous types of weather. So, in many areas of the region, especially in the most elevated areas, these synoptic and mesoscale situations generate snow precipitation. We should point out that snowfall is one of the principal meteorological risks of Castile and León. Thus, on average, in some mountainous areas there are more than 40 events of snowfall registered annually, with the month of January being the month in which the highest frequency of snowfall appears. The social repercussions of this snowfall are represented in the isolation of places, essentially mountainous, highways being blocked, increase in traffic accidents, etc. As proof of this, it is this type of episode that receives ample coverage by the media, which has a linear relationship with the social perception of risk. As such, the objective of the current work is to analyze the annual trend of days with snow in the different meteorological stations pertaining to AEMET placed in the Community. The period of study is from 1960-2010. Additionally, we have also evaluated trends in annual days of freezing temperature and annual absolute minimum temperature, with the objective of facilitating a meteorological interpretation of the trends obtained on days with snowfall. Finally, the results show that in the majority of stations, a significant negative trend in days with snowfall and annual days with freezing temperatures, and a positive trend in annual absolute minimum temperatures. However, we observed variability in the different regions in the area of study

L’évaluation et le traitement du nourrisson exposé au virus d’immunodéficience humaine de type 1

PubMed Central

2004-01-01

RÉSUMÉ Dans les pays industrialisés, des soins et un traitement sont offerts aux femmes enceintes et aux nourrissons, afin de faire chuter à 2 % ou moins le taux d’infection périnatale au virus d’immunodéficience humaine de type 1 (VIH-1). Le pédiatre joue un rôle de premier plan dans la prévention de la transmission du VIH-1 de la mère à l’enfant par le dépistage des nourrissons exposés au VIH dont l’infection au VIH de la mère n’a pas été diagnostiquée avant l’accouchement. Il prescrit une prophylaxie antirétrovirale à ces nourrissons, afin de réduire le risque d’acquisition de l’infection au VIH-1 et d’en éviter le plus possible la transmission par le lait maternel. De plus, le pédiatre peut soigner les nourrissons exposés au VIH-1 en les surveillant pour obtenir un dépistage précoce de l’infection au VIH-1 et évaluer les toxicités à court et à long terme de l’exposition aux antirétroviraux, assurer une chimioprophylaxie de la pneumonie à Pneumocystis et soutenir les familles qui vivent avec une infection au VIH-1, grâce à des conseils thérapeutiques aux parents ou aux soignants.

Developement of the Potassium-Argon Laser Experiment (KArLE) for In Situ Geochronology

NASA Technical Reports Server (NTRS)

Cohen, Barbara A.

2012-01-01

Absolute dating of planetary samples is an essential tool to establish the chronology of geological events, including crystallization history, magmatic evolution, and alteration. Thus far, radiometric geochronology of planetary samples has only been accomplishable in terrestrial laboratories on samples from dedicated sample return missions and meteorites. In situ instruments to measure rock ages have been proposed, but none have yet reached TRL 6, because isotopic measurements with sufficient resolution are challenging. We have begun work under the NASA Planetary Instrument Definition and Development Program (PIDDP) to develop the Potassium (K) - Argon Laser Experiment (KArLE), a novel combination of several flight-proven components that will enable accurate KAr isochron dating of planetary rocks. KArLE will ablate a rock sample, measure the K in the plasma state using laser-induced breakdown spectroscopy (LIBS), measure the liberated Ar using quadrupole mass spectrometry (QMS), and relate the two by measuring the volume of the abated pit using a optical methods such as a vertical scanning interferometer (VSI). Our preliminary work indicates that the KArLE instrument will be capable of determining the age of several kinds of planetary samples to 100 Myr, sufficient to address a wide range of geochronology problems in planetary science. Additional benefits derive from the fact that each KArLE component achieves analyses common to most planetary surface missions.

Fibre optique à la maison en Pays de Gex et de Bellegarde

ScienceCinema

None

2017-12-09

Le Syndicat Intercommunal d’Electricité de l’Ain(SIEA) déploie un réseau FTTH (Fiber To The Home) de fibres optiques dans le département de l’Ain vers l’ensemble des habitations. Le déploiement sur la zone pilote du Pays de Gex et du Bassin Bellegardien arrive dans la phase terminale vers les habitations. Le SIEA présentera ses activités, l’état du développement du réseau, les implications d’une connexion fibre optique et les procédures d’abonnement. La présentation sera donnée en Français. -------------------------------------------------------------------------------------------------------------------------------Public conference "Optical fiber To The Home in Pays de Gex et de Bellegarde" Michel Chanel et Jean Paul Goy (SIEA) Wednesday, 19th May at 11.30 hrs., Council Chamber, CERN The ‘’ Syndicat Intercommunal d’Electricité de l’Ain’’(SIEA) is deploying an optical fiber network FTTH (Fiber To The Home) in the Ain department towards the ensemble of houses. The installation on the pilot areas of Pays de Gex and Bassin Bellegardien is arriving in the phase of connecting houses. The SIEA will show its activities, the state of the network development, the implications of an optical fiber connection and the contract procedures. The presentation will be given in French

Fibre optique à la maison en Pays de Gex et de Bellegarde

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

2010-05-19

Le Syndicat Intercommunal d’Electricité de l’Ain(SIEA) déploie un réseau FTTH (Fiber To The Home) de fibres optiques dans le département de l’Ain vers l’ensemble des habitations. Le déploiement sur la zone pilote du Pays de Gex et du Bassin Bellegardien arrive dans la phase terminale vers les habitations. Le SIEA présentera ses activités, l’état du développement du réseau, les implications d’une connexion fibre optique et les procédures d’abonnement. La présentation sera donnée en Français. -------------------------------------------------------------------------------------------------------------------------------Public conference "Optical fiber To The Home in Pays de Gex et de Bellegarde" Michel Chanel et Jean Paul Goy (SIEA) Wednesday, 19th May at 11.30more » hrs., Council Chamber, CERN The ‘’ Syndicat Intercommunal d’Electricité de l’Ain’’(SIEA) is deploying an optical fiber network FTTH (Fiber To The Home) in the Ain department towards the ensemble of houses. The installation on the pilot areas of Pays de Gex and Bassin Bellegardien is arriving in the phase of connecting houses. The SIEA will show its activities, the state of the network development, the implications of an optical fiber connection and the contract procedures. The presentation will be given in French« less

Frequency Assignment, Sharing and Conservation in Systems (Aerospace). (l’Attribution, le partage et la conservation des frequences pour les systemes aeronautiques et spatiales)

DTIC Science & Technology

1999-01-01

que pour les installations et le personnel mis ä sa disposition. T- l Technical Evaluation Report of the RTO...radiocommunications sur le radar, on peut mettre en oeuvre des techniques de Formation de Faisceau par le Calcul qui permettent d’augmenter encore le niveau...plus 6loign6s pouvant fonctionner sur les mSmes canaux de frequence que le radar sans g£ne mutuelle1. equipements de radiocommunication

Le Chatelier's Principle and the Prediction Temperature on Solubilities.

ERIC Educational Resources Information Center

Fernandez-Prini, R.

1982-01-01

Discusses Le Chatelier's Principle from a thermodynamic perspective and applies it to the effect of temperature on the solubility of gases in liquids. Rationale of this discussion is to evaluate data in a previous article claimed to be contradictory to the Principle. (Author/JN)

Gravity in the Century of Light: The Gravitation Theory of Georges-Louis Le Sage

NASA Astrophysics Data System (ADS)

Evans, James

2006-05-01

Each generation of physicists, or natural philosophers, has sought to place universal gravitation in the context of its own worldview. Often this has entailed an effort to reduce gravitation to something more fundamental. But what is deemed fundamental has, of course, changed with time. Each generation attacked the problem of universal gravitation with the tools of its day and brought to bear the concepts of its own standard model. The most successful eighteenth-century attempt to provide a mechanical explanation of gravity was that of Georges-Louis Le Sage (1724-1803) of Geneva. Le Sage postulated a sea of ultramundane corpuscles, streaming in all directions and characterized by minute mass, great velocity, and complete inelasticity. Mostly these corpuscles just pass through gross bodies such as apples or planets, but a few are absorbed, leading to all the phenomena of attraction. In a voluminous correspondence with nearly all the savants of the day, Le Sage constantly reshaped his arguments for his system in order to appeal to metaphysicians, mechanicians and Newtonians of several varieties. Le Sage's theory is an especially interesting one, for several reasons. First, it serves as the prototype of a dynamical explanation of Newtonian gravity. Second, the theory came quite close to accomplishing its aim. Third, the theory had a long life and attracted comment by the leading physical thinkers of several successive generations, including Laplace, Kelvin, Maxwell and Feynman. Le Sage's theory therefore provides an excellent opportunity for the study of the evolution of attitudes toward physical explanation. The effects of national style in science and generational change take on a new clarity.

Maxillary distraction osteogenesis at Le Fort-I level induces bone apposition at infraorbital rim.

PubMed

Rattan, Vidya; Jena, Ashok Kumar; Singh, Satinder Pal; Utreja, Ashok Kumar

2014-09-01

The aim of this study is to evaluate whether there is any remodeling of bone at infraorbital rim following maxillary distraction osteogenesis (DO) at Le Fort-I level. Twelve adult subjects in the age range of 17-21 years with complete unilateral cleft lip and palate underwent advancement of the maxilla by DO. The effect of maxillary DO on the infraorbital rim remodeling was evaluated from lateral cephalograms recorded prior to the DO (T0), at the end of DO (T1), and at least 2-years after the DO (T2) by Walker's analysis. The ANOVA and two-tailed t test were used and probability value (P value) 0.05 was considered as statistically significant level. There was anterior movement of maxilla by 9.22 ± 3.27 mm and 7.67 ± 3.99 mm at the end of immediate (T1) and long-term (T2) follow-up of maxillary DO, respectively. The Walker's analysis showed 1.49 ± 1.22 mm and 2.31 ± 1.81 mm anterior movement of the infraorbital margin (Orbitale point) at the end of T1 and T2, respectively (P < 0.01). This apposition of bone at the infraorbital rim region further improved the facial profile of these patients. The advancement of maxilla by distraction osteogenesis at Le Fort-I level induced significant bone apposition at infraorbital rim. Patients with mild midface hypoplasia who would otherwise may be candidates for osteotomy at Le Fort-II or Le Fort-III level may benefit from maxillary distraction at Le Fort-I level.

Smoking and polymorphisms of fucosyltransferase gene Le affect success of H. pylori eradication with lansoprazole, amoxicillin, and clarithromycin.

PubMed Central

Matsuo, K.; Hamajima, N.; Ikehara, Y.; Suzuki, T.; Nakamura, T.; Matsuura, A.; Tajima, K.; Tominaga, S.

2003-01-01

Identification of factors influencing success of Helicobacter pylori (HP) eradication is important for clinical practice. We have prospectively conducted an HP eradication study in the Aichi Cancer Center with a total of 142 patients available for analysis. The overall success rate was 61.3% (95% confidence interval 52.7-69.3%). Smoking during the medication for eradication significantly decreased the success rate (42.9%), whereas smoking cessation during the treatment was associated with a similar rate as for non-smokers (66.7%). We also examined links between an eradication outcome and polymorphisms of Le, Se, IL1A, IL1B, IL1RN and MPO genes, but with one exception none showed any association. The non-functional le allele of Le polymorphisms, leading to decreased expression of Le(b) antigen to which HP attaches with adhesin, showed a beneficial effect for success. Although further clarification is necessary, our study indicated that smoking cessation and Le gene polymorphisms may affect the success rate of HP eradication. PMID:12729191

The Potassium-Argon Laser Experiment (KarLE): In Situ Geochronology for Mars and Beyond

NASA Technical Reports Server (NTRS)

Cohen, Barbara A.

2014-01-01

The search for life in the solar system depends upon discovering the right moments in planetary evolution: when habitable environments existed, when they declined, and when geologic processes operated to preserve traces of life after death. However, an incomplete knowledge of absolute Martian geochronology limits our ability to understand the timing of Martian evolutionary milestones, major climate changes, and stratigraphic epochs [1, 2]. Absolute dating relates these habitability markers to planetarywide geologic, atmospheric, and climate history places, and ties their occurrence to the history of the solar system, especially the Earth-Moon system and the timescale of evolution of life on Earth. KArLE is being developed to anchor the relative timeline of geological events to an absolute chronology that puts Mars into a wider solar system context. KArLE makes its measurements on rock samples that can be obtained by landers or rovers and inserted into a small, mechanically simple chamber. KArLE interrogates the samples using laser-induced breakdown spectrocopy (LIBS), mass spectrometry, and optical imaging. The KArLE experiment is flexible enough to accommodate any partner providing these instrument components, a creative approach that extends the ability of mission payloads to accomplish an additional highly-desirable science measurement for low cost and risk and minimal extra hardware.

"We Must Have Writers": An Introduction to the Narrative Rhetorical Theory of Meridel LeSueur.

ERIC Educational Resources Information Center

Allen, Julia M.

This paper examines the life and works of Meridel LeSueur, a colleague of Kenneth Burke, and herself a radical writer during the 1920s and 1930s. The paper states that LeSueur's primary aim was to establish an indigenous working-class culture to support working-class action. It notes that her arguments about writing build upon the rhetorical…

Tomato Prenylated RAB Acceptor Protein 1 Modulates Trafficking and Degradation of the Pattern Recognition Receptor LeEIX2, Affecting the Innate Immune Response

PubMed Central

Pizarro, Lorena; Leibman-Markus, Meirav; Schuster, Silvia; Bar, Maya; Meltz, Tal; Avni, Adi

2018-01-01

Plants recognize microbial/pathogen associated molecular patterns (MAMP/PAMP) through pattern recognition receptors (PRRs) triggering an immune response against pathogen progression. MAMP/PAMP triggered immune response requires PRR endocytosis and trafficking for proper deployment. LeEIX2 is a well-known Solanum lycopersicum RLP-PRR, able to recognize and respond to the fungal MAMP/PAMP ethylene-inducing xylanase (EIX), and its function is highly dependent on intracellular trafficking. Identifying protein machinery components regulating LeEIX2 intracellular trafficking is crucial to our understanding of LeEIX2 mediated immune responses. In this work, we identified a novel trafficking protein, SlPRA1A, a predicted regulator of RAB, as an interactor of LeEIX2. Overexpression of SlPRA1A strongly decreases LeEIX2 endosomal localization, as well as LeEIX2 protein levels. Accordingly, the innate immune responses to EIX are markedly reduced by SlPRA1A overexpression, presumably due to a decreased LeEIX2 availability. Studies into the role of SlPRA1A in LeEIX2 trafficking revealed that LeEIX2 localization in multivesicular bodies/late endosomes is augmented by SlPRA1A. Furthermore, inhibiting vacuolar function prevents the LeEIX2 protein level reduction mediated by SlPRA1A, suggesting that SlPRA1A may redirect LeEIX2 trafficking to the vacuole for degradation. Interestingly, SlPRA1A overexpression reduces the amount of several RLP-PRRs, but does not affect the protein level of receptor-like kinase PRRs, suggesting a specific role of SlPRA1A in RLP-PRR trafficking and degradation. PMID:29545816

4. Historic American Buildings Survey, Arthur W. LeBoeuf, Photographer, 1937 ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

4. Historic American Buildings Survey, Arthur W. LeBoeuf, Photographer, 1937 DETAIL OF WINDOW BREAKING INTO PEDIMENT. - First Congregational Church, 301 Benefit Street, Providence, Providence County, RI

Repenser ensemble le concept d'autonomie alimentaire.

PubMed

Bélisle, Micheline; Labarthe, Jenni; Moreau, Cynthia; Landry, Elise; Adam, Gracia; Bourque Bouliane, Mijanou; Dupéré, Sophie

2017-03-01

C'est au cœur du projet de recherche-action participative « Vers une autonomie alimentaire pour tou-te-s : agir et vivre ensemble le changement » (VAATAVEC) que s'est élaborée une définition nouvelle et évolutive de l'autonomie alimentaire. De ce projet regroupant des personnes en situation de pauvreté, chercheurs et intervenants, a émergé une conceptualisation résultant à la fois d'une méthode de réflexion collective et d'un processus d'analyse collective, inspiré de la théorisation ancrée et de l'analyse conceptualisante de Paillé et Mucchielli (2003). Le recours à l'expertise des personnes en situation de pauvreté, expertes du vécu de l'insécurité alimentaire, a contribué à ancrer cette définition dans les causes structurelles de l'insécurité alimentaire dans une perspective de développement d'un pouvoir d'agir collectif, de toutes les personnes concernées. Il en résulte une définition de l'autonomie alimentaire d'où ressort une contribution surtout méthodologique et théorique.

MoLeNET Mobile Learning Conference 2009: Research Papers

ERIC Educational Resources Information Center

Guy Parker, Ed.

2010-01-01

The Mobile Learning Network (MoLeNET) is a unique collaborative approach to encouraging, supporting, expanding and promoting mobile learning, primarily in English post-14 education and training, via supported shared cost mobile learning projects. Collaboration at national level involves participating institutions and the Learning and Skills…

FOREWORD: International Conference on Heavy Ion Collisions in the LHC Era

NASA Astrophysics Data System (ADS)

Arleo, Francois; Salgado, Carlos A.; Tran Thanh Van, Jean

2013-03-01

The International Conference on Heavy Ion Collisions in the LHC Era was held in Quy Nhon, Vietnam, on 16-20 July 2012. The series Rencontres du Vietnam, created by Jean Tran Thanh Van in 1993, consists of international meetings aimed to stimulate the development of advanced research in Vietnam and more generally in South East Asia, and to establish collaborative research networks with Western scientific communities. This conference, as the whole series, also supports the International Center for Interdisciplinary Science Education being built in Quy Nhon. The articles published in this volume present the latest results from the heavy-ion collision programs of RHIC and LHC as well as the corresponding theoretical interpretation and future perspectives. Lower energy nuclear programs were also reviewed, providing a rather complete picture of the state-of-the-art in the field. We wish to thank the sponsors of the Conference on Heavy Ion Collisions in the LHC Era: the European Research Council; Xunta de Galicia (Spain); EMMI (Germany) and Agence Nationale de la Recherche (France) François Arleo (Laboratoire d'Annecy-le-Vieux de Physique Théorique, France) Francois Arleo, Carlos A Salgado and Jean Tran Thanh Van Conference photograph

In Situ Geochronology on the Mars 2020 Rover with KArLE (Potassium-Argon Laser Experiment)

NASA Technical Reports Server (NTRS)

Cohen, B. A.; Swindle, T. D.; Roark, S. E.

2014-01-01

If extinct and/or extant life is discovered on Mars, knowledge of the chronology of the biosphere will be of paramount importance. KArLE will provide absolute ages of Mars 2020 rocks, which will allow us to understand them in the context of Mars' geologic history, connect them to other landing sites, and compare Martian epochs of habitability with the Earth's history and evolution of life. KArLE significantly enhances the ability of Mars 2020 to meet its science objectives by performing in situ age dating on key lithologies, enabling targeted searches for ancient biosignatures and increasing the chances of identifying evidence for Martian microbial life. The KArLE investigation makes its measurements on a core sample obtained with the rover drill, inserted into a small, mechanically simple chamber, followed by interrogation by laser-induced breakdown spectroscopy (LIBS), mass spectrometry, and optical imaging. The KArLE experiment is flexible enough to accommodate any partner providing these instrument components, a creative approach that extends the ability of the Mars 2020 payload to accomplish an additional highly-desirable science measurement for low cost and risk and minimal extra hardware.

Some special features of the le chatelier-braun principle

NASA Astrophysics Data System (ADS)

Nesis, E. I.; Skibin, Yu. N.

2000-07-01

The relaxation reaction of a system that follows from the Le Chatelier-Braun principle and weakens the result of an external influence turns out to be more intense under a complex action. A method for quantitative determination of the weakening effect for simple and complex actions is suggested.

Surgical management of patients with a history of early Le Fort III advancement after they have attained skeletal maturity.

PubMed

Caterson, E J; Shetye, Pradip R; Grayson, Barry H; McCarthy, Joseph G

2013-10-01

The classic Le Fort III procedure was recommended in syndromic craniosynostotic children to reduce exorbitism, improve airway function, and decrease dysmorphism. This study reports on a cohort of syndromic craniosynostosis patients who have undergone early primary subcranial (classic Tessier) Le Fort III advancement and who have been followed longitudinally through skeletal maturity and beyond. In this study, the Le Fort III advancements all occurred between the ages of 3 to 5 years, with a mean age of 4.6 years. Subsequently, these early Le Fort III patients were followed throughout development with longitudinal dental, medical, radiographic, and photographic evaluations conducted through skeletal maturity and beyond. For study inclusion, the patients had to have preoperative medical photographs and cephalometric studies at 6 months and 1, 5, and 10 years postoperatively after the primary Le Fort III advancement as well as cephalometric documentation 6 months and 1 year after the secondary midface advancement after skeletal maturity. After early or primary Le Fort III advancement, there was no evidence of relapse and only minimal anterior or horizontal postoperative growth of the midface. However, there was also a return of occlusal disharmony from "anticipated" mandibular growth, approaching a maximum at skeletal maturity. The dysmorphic concave facial profile and malocclusion, and airway and ocular considerations, provided the impetus for secondary midface surgery after skeletal maturity was attained. The data demonstrate that early Le Fort III advancement performed before the age of mixed dentition does not obviate the need for a secondary advancement after skeletal maturity is reached. Therapeutic, IV.

Influence of third molars in Le Fort 1 osteotomy

PubMed Central

Balaji, S. M.

2011-01-01

Background: The influence of maxillary third molar (M3) on the outcomes of Le Fort 1 osteotomy is not deeply investigated. Aim: To investigate the influence of M3 on Le Fort 1 osteotomies. Setting: Tertiary Referral Center, operated by a single surgeon, prospective study. Period: January 2005 to December 2010. Patients: Consecutive Le Fort 1 osteotomy patients with both M3. Predictor Variable: Gender, position, M3 root morphology, and degree of impaction. Outcome Variable: Time taken after all osteotomy cuts to point of time when maxilla is placed in predetermined plane. Result: A total of 658 M3 in line of cut were studied. Of all M3, 312 were impacted, 28.9% were partially impacted and 23.7% were erupted. Of all the M3, 2.9% had their cuspal tips above the horizontal cut, 13.8% along the line of cut, and in 20.7% below the line but not erupted. Buccoverted tooth took shortest time (7.74 minutes), while palatoversion required more time (8.44 minutes) (P = 0.000). When the cuspal tip of M3 was located above the horizontal line of cut, the mean time required to achieve the planned position was 7 minutes, while the completely erupted teeth took a mean of 8.24 minutes (P = 0.000). Conclusion: When the M3 is placed higher, it takes lesser time to prepare basal bone to receive the maxilla at its predetermined level. Angulation of M3 influences the outcome. Deeply placed M3 reduces the manipulation of the greater pterygoid palatine vessels in the area thereby minimizing the bleeding in the surgical field. PMID:23482647

Le premier examen gynécologique idéal imaginé par les jeunes filles

PubMed Central

Freyens, Anne; Dejeanne, Mélanie; Fabre, Elise; Rouge-Bugat, Marie-Eve; Oustric, Stéphane

2017-01-01

Résumé Objectif Explorer les représentations sur l’examen gynécologique (EG) et identifier les critères nécessaires à son bon déroulement chez des adolescentes n’ayant pas encore vécu cet examen. Type d’étude Enquête qualitative par entrevues semi-dirigées. Contexte Midi-Pyrénées (France) et Auvergne (France). Participants Jeunes filles de 15 à 19 ans qui n’ayant pas vécu l’EG. Méthodes Le mode de recrutement de l’échantillon a été double : sélection des jeunes filles par la technique boule-de-neige et sélection par la technique d’échantillonnage ciblé jusqu’à l’obtention de la saturation des données tout en cherchant la variation maximale dans les profils des sujets. Les questions ouvertes portaient sur les sources d’informations, les connaissances, les critères de bon déroulement et l’imaginaire autour de l’EG. Le verbatim a fait l’objet d’une analyse longitudinale immédiate rassemblant le contexte (notes des chercheurs) et les idées principales de l’entretien. Une analyse transversale thématique a été réalisée. Principales constatations Une méconnaissance générale des jeunes filles sur l’EG entretenait l’imaginaire autour de cet examen perçu comme obligatoire. L’EG idéal, selon les jeunes filles interrogées, aurait lieu chez une jeune fille qui se sentirait prête, informée préalablement, pouvant être accompagnée selon son souhait. Cet examen se déroulerait dans un environnement chaleureux et confortable afin de diminuer le sentiment de vulnérabilité. La qualité du lien avec le médecin conditionnerait l’acceptation de cet examen par les jeunes filles. Conclusion Une consultation dédiée à l’information, préalable à la consultation où a lieu l’EG, permettrait de diminuer les appréhensions, d’améliorer les connaissances des jeunes filles et de favoriser le bon déroulement du futur premier EG tant pour le médecin que pour la patiente. PMID:28807971

LeCTR1, a Tomato CTR1-Like Gene, Demonstrates Ethylene Signaling Ability in Arabidopsis and Novel Expression Patterns in Tomato1

PubMed Central

Leclercq, Julie; Adams-Phillips, Lori C.; Zegzouti, Hicham; Jones, Brian; Latché, Alain; Giovannoni, James J.; Pech, Jean-Claude; Bouzayen, Mondher

2002-01-01

LeCTR1 was initially isolated by both differential display reverse transcriptase-polymerase chain reaction screening for tomato (Lycopersicon esculentum) fruit ethylene-inducible genes and through homology with the Arabidopsis CTR1 cDNA. LeCTR1 shares strong nucleotide sequence homology with Arabidopsis CTR1, a gene acting downstream of the ethylene receptor and showing similarity to the Raf family of serine/threonine protein kinases. The length of the LeCTR1 transcribed region from ATG to stop codon (12,000 bp) is more than twice that of Arabidopsis CTR1 (4,700 bp). Structural analysis reveals perfect conservation of both the number and position of introns and exons in LeCTR1 and Arabidopsis CTR1. The introns in LeCTR1 are much longer, however. To address whether this structural conservation is indicative of functional conservation of the corresponding proteins, we expressed LeCTR1 in the Arabidopsis ctr1-1 (constitutive triple response 1) mutant under the direction of the 35S promoter. Our data clearly show that ectopic expression of LeCTR1 in the Arabidopsis ctr1-1 mutant can restore normal ethylene signaling. The recovery of normal ethylene sensitivity upon heterologous expression of LeCTR1 was also confirmed by restored glucose sensitivity absent in the Arabidopsis ctr1-1 mutant. Expression studies confirm ethylene responsiveness of LeCTR1 in various tissues, including ripening fruit, and may suggest the evolution of alternate regulatory mechanisms in tomato versus Arabidopsis. PMID:12427980

A Multistep Equilibria-Redox-Complexation Demonstration to Illustrate Le Chatelier's Principle.

ERIC Educational Resources Information Center

Berger, Tomas G.; Mellon, Edward K.

1996-01-01

Describes a process that can be used to illustrate a number of chemical principles including Le Chatelier's principle, redox chemistry, equilibria versus steady state situations, and solubility of species. (JRH)

Nitric oxide modulates Lycopersicon esculentum C-repeat binding factor 1 (LeCBF1) transcriptionally as well as post-translationally by nitrosylation.

PubMed

Kashyap, Prakriti; Sehrawat, Ankita; Deswal, Renu

2015-11-01

Nitric oxide (NO) production increases in the cold stress. This cold enhanced NO manifests its effect either by regulating the gene expression or by modulating proteins by NO based post-translational modifications (PTMs) including S-nitrosylation. CBF (C-repeat binding factor) dependent cold stress signaling is most studied cold stress-signaling pathway in plants. SNP (sodium nitroprusside, a NO donor) treatment to tomato seedlings showed four fold induction of LeCBF1 (a cold inducible CBF) transcript in cold stress. S-nitrosylation as PTM of CBF has not been analyzed till date. In silico analysis using GPS-SNO 1.0 software predicted Cys 68 as the probable site for nitrosylation in LeCBF1. The 3D structure and motif prediction showed it to be present in the beta hairpin loop and hence available for S-nitrosylation. LeCBF1 was cloned and expressed in Escherichia coli. LeCBF1 accumulated in the inclusion bodies, which were solubilized under denaturing conditions and purified after on column refolding by Ni-NTA His tag affinity chromatography. Purified LeCBF1 resolved as a 34 kDa spot with a slightly basic pI (8.3) on a 2-D gel. MALDI-TOF mass spectrometry identified it as LeCBF1 and western blotting using anti-LeCBF1 antibodies confirmed its purification. Biotin switch assay and neutravidin affinity chromatography showed LeCBF1 to be S-nitrosylated in presence of GSNO (NO donor) as well as endogenously (without donor) in cold stress treated tomato seedlings. Dual regulation of LeCBF1 by NO at both transcriptional as well as post-translational level (by S-nitrosylation) is shown for the first time. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

Séroprévalence de l’AgHBs chez la femme enceinte dans le centre du Maroc

PubMed Central

Sbiti, Mohammed; Khalki, Hanane; Benbella, Imane; louzi, Lhoussaine

2016-01-01

La transmission materno-fœtale du virus de l'hépatite B (VHB) est un problème qui préoccupe toujours les autorités sanitaires à travers le monde et suscite la mise en place de mesures préventives renforcées. Le statut réplicatif du virus chez la mère séropositive, évalué par la positivité de l'AgHbe et le taux de la charge virale, conditionne le risque de contamination qui est plus important en période péri-natale. Les mères porteuses chroniques du VHB constituent un véritable réservoir de la transmission verticale de cette infection. Nous avons étudié, à travers cette enquête sur 1120 femmes enceintes Marocaines, la séroprévalence de l'AgHBs qui était de 2,35%, dans le but d'alimenter les données nationales sur ce sujet. Parmi ces femmes séropositives pour l'AgHBs, 79,1% avaient un AgHBe négatif et ont bénéficié d'une recherche moléculaire qui s'est révélée positive dans 89,4% des cas. La vaccination de la femme en âge de procréer est l'un des piliers majeurs de la prévention de la transmission verticale du VHB, seulement 2,4% de nos patientes étaient vaccinées. Ceci relève l'intérêt du dépistage au cours de la grossesse, qui doit se focaliser sur la sensibilisation à la vaccination de femmes séronégatives, et le suivi par biologie moléculaire des mères séropositives dans le but d'instaurer un traitement prophylactique adéquat. PMID:27795784

Les enfants et le theatre (Children and the Theater).

ERIC Educational Resources Information Center

Ferrari, Josephine

1980-01-01

Describes a project involving the presentation of "Le petit prince" as an exercise in dramatics by children in a French-Italian bilingual education class. Two steps in the process are discussed: (1) the study of the text, and (2) the activities involved in getting the play ready for performance. (AMH)

1. Historic American Buildings Survey, Arthur W. LeBoeuf, Photographer, 1937 ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. Historic American Buildings Survey, Arthur W. LeBoeuf, Photographer, 1937 DETAIL OF MANTEL. - John Mason House (Mantel), Weybosset Street (moved to Rhode Island School of Design), Providence, Providence County, RI

Appendicite aigue non compliquée: y a-t- il une place pour le traitement conservateur

PubMed Central

El Khader, Ahmed; Lahkim, Mohamed; El Barni, Rachid; Achour, Abdessamad

2015-01-01

Le but de cette étude a été d’évaluer l'efficacité de l'antibiothérapie seule dans le traitement des appendicites aigues non compliquées. C'est une étude prospective, intéressant 68 patients ayant eu une appendicite aigue simple, de confirmation radiologique, traités par l'amoxicilline associée à l'acide clavulanique pendant 10 jours. L'appendicectomie a été réalisée en cas d'aggravation ou en cas de non amélioration au bout de 48heures de traitement. Le traitement conservateur a été efficace dans 82,35% avec une résolution complète des symptômes chez 56 patients. Les 12 cas restants (17,65%) ont subit une appendicectomie. l'appendicite a été gangréneuse dans 8 cas et phlegmoneuse dans 4 cas. Cinq des 56 patients, qui ont bien évolué sous traitement conservateur, ont été réadmis et opérés pour récidive, soit 8,9%. Deux cas ont eu une appendicite compliquée. L'appendicectomie reste le traitement de référence pour l'appendicite aigue, mais le traitement antibiotique peut être proposé en première intension à des patients présentant une appendicite aigue non compliquée. PMID:26327981

The LE1 Bacteriophage Replicates as a Plasmid within Leptospira biflexa: Construction of an L. biflexa-Escherichia coli Shuttle Vector

PubMed Central

Girons, Isabelle Saint; Bourhy, Pascale; Ottone, Catherine; Picardeau, Mathieu; Yelton, David; Hendrix, Roger W.; Glaser, Philippe; Charon, Nyles

2000-01-01

We have discovered that LE1, one of the plaque-forming phages previously described as lytic for the Leptospira biflexa saprophytic spirochete (I. Saint Girons, D. Margarita, P. Amouriaux, and G. Baranton, Res. Microbiol. 141:1131–1138, 1990), was indeed temperate. LE1 was found to be unusual, as Southern blot analysis indicated that it is one of the few phages to replicate in the prophage state as a circular plasmid. The unavailability of such small endogenous replicons has hindered genetic experimentation in Leptospira. We have developed a shuttle vector with DNA derived from LE1. Random LE1 DNA fragments were cloned into a pGEM 7Zf(+) derivative devoid of most of the bla gene but carrying a kanamycin resistance marker from the gram-positive bacterium Enterococcus (Streptococcus) faecalis. These constructs were transformed into L. biflexa strain Patoc 1 by electroporation, giving rise to kanamycin-resistant transformants. A 2.2-kb fragment from LE1 was responsible for replication of the vector in L. biflexa. However, a larger region including an intact parA gene homologue was necessary for the stability of the shuttle vector. Direct repeats and AT-rich regions characterized the LE1 origin of replication. Our data indicate that the replicon derived from the LE1 leptophage, together with the kanamycin resistance gene, is a promising tool with which to develop the genetics of Leptospira species. PMID:11004167

LISA 8 Science Organizing Committee and Local Organizing Committee LISA 8 Science Organizing Committee and Local Organizing Committee

NASA Astrophysics Data System (ADS)

2011-05-01

Science Organising Committee (SOC) Tom Abel, Stanford University Odylio Aguiar, Instituto Nacional de Pesquisas Espaciais Tal Alexander, Wizemann Institute Peter Bender, University of Colorado Pierre Binetruy, APC - College de France Sasha Buchman, Stanford University Robert Byer, Stanford University Manuela Campanelli, University of Texas Joan Centrella, NASA/Goddard Massimo Cerdonio, University of Padova Eugenio Coccia, University of Roma-2 Neil Cornish, Montana State University Michael Cruise, University of Birmingham Curt Cutler, NASA/JPL Karsten Danzmann, University of Hannover Sam Finn, Penn State University Jens Gundlach, NPL Gerhard Heinzel, Max-Planck-Institut fuer Gravitationsphysik Craig Hogan, University of Washington Jim Hough, University of Glasgow Scott Hughes, MIT Oliver Jennrich, ESTEC Philippe Jetzer, University Zurich Seiji Kawamura, National Observatory, Japan Alberto Lobo, ICE-CSIC and IEEC Avi Loeb, Harvard University Piero Madau, Lick Observatory Yannick Mellier, IAP, Paris Peter Michelson, Stanford University Guido Mueller, University of Florida Sterl Phinney, Caltech Tom Prince, NASA/JPL Doug Richstone, University of Michigan Bernard Schutz, AEI Potsdam Tuck Stebbins, NASA/Goddard Tim Sumner, Imperial College, London Ke-Xun Sun, Stanford University Kip Thorne, Caltech Michele Vallisneri, NASA/JPL Alberto Vecchio, University of Birmingham Jean-Yves Vinet, OCA, Nice Stefano Vitale, University of Trento Rai Weiss, MIT Nick White, NASA/Goddard Local Organising Committee (LOC) Sasha Buchman (Stanford University) Robert Byer (Stanford University) Sara Charbonneau-Lefort (Stanford University) Nancy Christianson (Stanford University) John Conklin (Stanford University) Dan DeBra (Stanford University) Jan Goebel (Stanford University) Vivian Drew (Stanford University) Ke-Xun Sun (Stanford University) Lucy Zhou (Stanford University) Andrea Zoellner (Stanford University)

COMMITTEES: LISA 7 Science Organizing Committee and Local Organizing Committee LISA 7 Science Organizing Committee and Local Organizing Committee

NASA Astrophysics Data System (ADS)

2009-05-01

Science Organising Committee (SOC) Pierre Binetruy, APC - College de France Massimo Cerdonio, University of Padova Karsten Danzmann, AEI/University of Hannover Mike Cruise, University of Birmingham Jim Hough, University of Glasgow Oliver Jennrich, ESTEC Philippe Jetzer, University Zurich Alberto Lobo (Chair), ICE-CSIC and IEEC Yannick Mellier, IAP, Paris Bernard Schutz, AEI Potsdam Tim Sumner, Imperial College, London Jean-Yves Vinet, OCA, Nice Stefano Vitale, University of Trento Peter Bender, University of Colorado Sasha Buchman, Stanford University Joan Centrella, NASA/Goddard Neil Cornish, Montana State University Curt Cutler, NASA/JPL Sam Finn, Penn State University Jens Gundlach, NPL Craig Hogan, University of Washington Scott Hughes, MIT Piero Madau, Lick Observatory Tom Prince, NASA/JPL Sterl Phinney, Caltech Doug Richstone, University of Michigan Tuck Stebbins, NASA/Goddard Kip Thorne, Caltech Roger Blandford, Stanford University Eugenio Coccia, University of Roma-2 Carlos F Sopuerta,ICE-CSIC and IEEC Enrique Garcia-Berro, Universitat Politècnica de Catalunya, Barcelona Seiji Kawamura, National Observatory, Japan Jay Marx, LIGO Laboratory Stephen Merkowitz, NASA/Goddard Benoit Mours, Laboratoire d'Annec Gijs Nelemans, IMAPP, Nijmegen Enric Verdaguer, University of Barcelona Clifford M Will, Washington University, St Louis Local Organising Committee (LOC) Anna Bertolín (IEEC) Priscilla Cañizares (ICE-CSIC and IEEC) Carlos F Sopuerta (ICE-CSIC and IEEC) Ivan Lloro (ICE-CSIC and IEEC),Chair Alberto Lobo (ICE-CSIC and IEEC) Nacho Mateos (ICE-CSIC and IEEC) Pilar Montes (IEEC) Miquel Nofrarias (IEEC) Juan Ramos-Castro (Universitat Politècnica de Catalunya) Josep Sanjuán (IEEC)

Cloning, Characterization and Effect of TmPGRP-LE Gene Silencing on Survival of Tenebrio Molitor against Listeria monocytogenes Infection

PubMed Central

Tindwa, Hamisi; Patnaik, Bharat Bhusan; Kim, Dong Hyun; Mun, Seulgi; Jo, Yong Hun; Lee, Bok Luel; Lee, Yong Seok; Kim, Nam Jung; Han, Yeon Soo

2013-01-01

Peptidoglycan recognition proteins (PGRPs) are a family of innate immune molecules that recognize bacterial peptidoglycan. PGRP-LE, a member of the PGRP family, selectively binds to diaminopimelic acid (DAP)-type peptidoglycan to activate both the immune deficiency (Imd) and proPhenoloxidase (proPO) pathways in insects. A PGRP-LE-dependent induction of autophagy to control Listeria monocytogenes has also been reported. We identified and partially characterized a novel PGRP-LE homologue, from Tenebrio molitor and analyzed its functional role in the survival of the insect against infection by a DAP-type PGN containing intracellular pathogen, L. monocytogenes. The cDNA is comprised of an open reading frame (ORF) of 990 bp and encodes a polypeptide of 329 residues. TmPGRP-LE contains one PGRP domain, but lacks critical residues for amidase activity. Quantitative RT-PCR analysis showed a broad constitutive expression of the transcript at various stages of development spanning from larva to adult. RNAi mediated knockdown of the transcripts, followed by a challenge with L. monocytogenes, showed a significant reduction in survival rate of the larvae, suggesting a putative role of TmPGRP-LE in sensing and control of L. monocytogenes infection in T. molitor. These results implicate PGRP-LE as a defense protein necessary for survival of T. molitor against infection by L. monocytogenes. PMID:24240808

Cloning, characterization and effect of TmPGRP-LE gene silencing on survival of Tenebrio molitor against Listeria monocytogenes infection.

PubMed

Tindwa, Hamisi; Patnaik, Bharat Bhusan; Kim, Dong Hyun; Mun, Seulgi; Jo, Yong Hun; Lee, Bok Luel; Lee, Yong Seok; Kim, Nam Jung; Han, Yeon Soo

2013-11-14

Peptidoglycan recognition proteins (PGRPs) are a family of innate immune molecules that recognize bacterial peptidoglycan. PGRP-LE, a member of the PGRP family, selectively binds to diaminopimelic acid (DAP)-type peptidoglycan to activate both the immune deficiency (Imd) and proPhenoloxidase (proPO) pathways in insects. A PGRP-LE-dependent induction of autophagy to control Listeria monocytogenes has also been reported. We identified and partially characterized a novel PGRP-LE homologue, from Tenebrio molitor and analyzed its functional role in the survival of the insect against infection by a DAP-type PGN containing intracellular pathogen, L. monocytogenes. The cDNA is comprised of an open reading frame (ORF) of 990 bp and encodes a polypeptide of 329 residues. TmPGRP-LE contains one PGRP domain, but lacks critical residues for amidase activity. Quantitative RT-PCR analysis showed a broad constitutive expression of the transcript at various stages of development spanning from larva to adult. RNAi mediated knockdown of the transcripts, followed by a challenge with L. monocytogenes, showed a significant reduction in survival rate of the larvae, suggesting a putative role of TmPGRP-LE in sensing and control of L. monocytogenes infection in T. molitor. These results implicate PGRP-LE as a defense protein necessary for survival of T. molitor against infection by L. monocytogenes.

Analyse de L'ancrage des Vortex Intergrains pour le Yttrium BARYUM(2) CUIVRE(3) OXYGENE(7) Polycristallin

NASA Astrophysics Data System (ADS)

Fournier, Patrick

Le Modele de l'Etat Critique Generalise (MECG) est utilise pour decrire les proprietes magnetiques et de transport du YBa_2Cu_3O _7 polycristallin. Ce modele empirique permet de relier la densite de courant critique a la densite de lignes de flux penetrant dans la region intergrain. Deux techniques de mesures sont utilisees pour caracteriser nos materiaux. La premiere consiste a mesurer le champ au centre d'un cylindre creux en fonction du champ magnetique applique pour des temperatures comprises entre 20 et 85K. En variant l'epaisseur de la paroi du cylindre creux, il est possible de suivre l'evolution des cycles d'hysteresis et de determiner des champs caracteristiques qui varient en fonction de cette dimension. En utilisant un lissage des resultats experimentaux, nous determinons J _{co}, H_ {o} et n, les parametres du MECG. La forme des cylindres, avec une longueur comparable au diametre externe, entrai ne la presence d'un champ demagnetisant qui peut etre inclus dans le modele theorique. Ceci nous permet d'evaluer la fraction du volume ecrante, f _{g}, ainsi que le facteur demagnetisant N. Nous trouvons que J_{ co}, H_{o} et f_{g} dependent de la temperature, tandis que n et N (pour une epaisseur de paroi fixe) n'en dependent pas. La deuxieme technique consiste a mesurer le courant critique de lames minces en fonction du champ applique pour differentes temperatures. Nous utilisons un montage que nous avons developpe permettant d'effectuer ces mesures en contact direct avec le liquide refrigerant, i.e. dans l'azote liquide. Nous varions la temperature du liquide en variant la pression du gaz au-dessus du bain d'azote. Cette methode nous permet de balayer des temperatures entre 65K et la temperature critique du materiau ({~ }92K). Nous effectuons le lissage des courbes de courant critique en fonction du champ applique encore a l'aide du MECG, pour a nouveau obtenir ses parametres. Pour trois echantillons avec des traitements thermiques differents, les parametres

Intraday LeBaron effects

PubMed Central

Bianco, Simone; Corsi, Fulvio; Renò, Roberto

2009-01-01

We study the relation at intraday level between serial correlation and volatility of the Standard and Poor (S&P) 500 stock index futures returns. At daily and weekly levels, serial correlation and volatility forecasts have been found to be negatively correlated (LeBaron effect). After finding a significant attenuation of the original effect over time, we show that a similar but more pronounced effect holds by using intraday measures, by such as realized volatility and variance ratio. We also test the impact of unexpected volatility, defined as the part of volatility which cannot be forecasted, on the presence of intraday serial correlation in the time series by employing a model for realized volatility based on the heterogeneous market hypothesis. We find that intraday serial correlation is negatively correlated to volatility forecasts, whereas it is positively correlated to unexpected volatility.

The Center for Learning Technologies in Urban Schools (LeTUS) Program[R]. What Works Clearinghouse Intervention Report

ERIC Educational Resources Information Center

What Works Clearinghouse, 2012

2012-01-01

The "LeTUS" program is a three-year, project-based, technology-integrated middle school science curriculum for grades 6-8. The "LeTUS" program is composed of multiple units, each lasting between eight and ten weeks. Topics include global warming, water and air quality, force and motion, communicable diseases, and ecological…

Le rôle du soutien parental dans la relation entre la victimisation homophobe, l’homophobie intériorisée et la détresse psychologique chez les jeunes de minorités sexuelles (JMS) : une approche de médiation modérée

PubMed Central

Bergeron, Félix-Antoine; Blais, Martin; Hébert, Martine

2016-01-01

Résumé Cet article explore le rôle modérateur du soutien parental dans les relations entre la victimisation homophobe, l’homophobie intériorisée et la détresse psychologique chez des jeunes de minorités sexuelles (JMS), que l’on dit aussi lesbiennes, gais, bisexuels ou en questionnement. Il vise à 1) documenter la prévalence des différentes formes de victimisation homophobe vécue par les JMS, et ce, selon le genre et l’âge et 2) à explorer l’effet modérateur du soutien parental dans la relation entre la victimisation homophobe, l’homophobie intériorisée et la détresse psychologique. Un échantillon de 228 JMS âgés de 14 à 22 ans, non exclusivement hétérosexuels, recrutés en milieu communautaire dans le cadre de l’enquête sur le Parcours Amoureux des Jeunes (PAJ) du Québec a été analysé. L’impact de la victimisation homophobe, du soutien parental, de l’homophobie intériorisée sur la détresse psychologique est exploré par un modèle de régression linéaire avec effets de médiation modérée. Le rôle modérateur du soutien parental est confirmé dans la relation entre la victimisation homophobe et la détresse psychologique. Ces variables peuvent constituer des leviers pour prévenir les effets négatifs des préjudices homophobes sur la santé mentale des JMS. PMID:26966851

Etudes optiques de nouveaux materiaux laser: Des orthosilicates dopes a l'ytterbium: Le yttrium (lutetium,scandium) pentoxide de silicium

NASA Astrophysics Data System (ADS)

Denoyer, Aurelie

La decouverte et l'elaboration de nouveaux materiaux laser solides suscitent beaucoup d'interet parmi la communaute scientifique. En particulier les lasers dans la gamme de frequence du micron debouchent sur beaucoup d'applications, en telecommunication, en medecine, dans le domaine militaire, pour la, decoupe des metaux (lasers de puissance), en optique non lineaire (doublage de frequence, bistabilite optique). Le plus couramment utilise actuellement est le Nd:YAG dans cette famille de laser, mais des remplacants plus performants sont toujours recherches. Les lasers a base d'Yb3+ possedent beaucoup d'avantages compares aux lasers Nd3+ du fait de leur structure electronique simple et de leur deterioration moins rapide. Parmi les matrices cristallines pouvant accueillir l'ytterbium, les orthosilicates Yb:Y 2SiO5, Yb:Lu2SiO5 et Yb:Sc2SiO 5 se positionnent tres bien, du fait de leur bonne conductivite thermique et du fort eclatement de leur champ cristallin necessaire a l'elaboration de lasers quasi-3 niveaux. De plus l'etude fine et systematique des proprietes microscopiques de nouveaux materiaux s'avere toujours tres interessante du point de vue de la recherche fondamentale, c'est ainsi que de nouveaux modeles sont concus (par exemple pour le champ cristallin) ou que de nouvelles proprietes inhabituelles sont decouvertes, menant a de nouvelles applications. Ainsi d'autres materiaux dopes a l'ytterbium sont connus pour leurs proprietes de couplage electron-phonon, de couplage magnetique, d'emission cooperative ou encore de bistabilite optique, mais ces proprietes n'ont encore jamais ete mises en evidence dans Yb:Y 2SiO5, Yb:Lu2SiO5 et Yb:Sc2SiO 5. Ainsi, cette these a pour but l'etude des proprietes optiques et des interactions microscopiques dans Yb:Y2SiO 5, Yb:Lu2SiO5 et Yb:Sc2SiO5. Nous utilisons principalement les techniques d'absorption IR et de spectroscopie Raman pour determiner les excitations du champ cristallin et les modes de vibration dans le materiau

Rôle des forêts plantées dans l’économie forestière mondiale

Treesearch

Joseph Buongiorno; Shushuai Zhu

2013-01-01

Les forets plantees, constituees par pl antati on ou ensemencemen t, jouen t un role de plus en plus important dans l'economie foresti ere mondia le, dans I a conservation des ressources, et dans Ia lu tte contre le changement cli matique. Au nivea u mondial , elles occupent 258 million d'ha, soit 6% de Ia co u verture forestiere...

Update on Development of the Potassium-Argon Laser Experiment (KArLE) Instrument for In Situ Geochronology

NASA Technical Reports Server (NTRS)

Cohen, Barbara A.; Li, Z.-H.; Miller, J. S.; Brinckerhoff, W. B.; Clegg, S. M.; Mahaffy, P. R.; Swindle, T. D.; Wiens, R. C.

2013-01-01

Absolute dating of planetary samples is an essential tool to establish the chronology of geological events, including crystallization history, magmatic evolution, and alteration. We are addressing this challenge by developing the Potassium (K) -- Argon Laser Experiment (KArLE), building on previous work to develop a K-Ar in situ instrument. KArLE ablates a rock sample, determines the K in the plasma state using laser-induced breakdown spectroscopy (LIBS), measures the liberated Ar using quadrupole mass spectrometry (QMS), and relates the two by the volume of the ablated pit using laser confocal microscopy (LCM). Our goal is for the KArLE instrument to be capable of determining the age of several kinds of planetary samples to address a wide range of geochronolgy problems in planetary science.

Le potentiel de l'asteroseismologie pour les etoiles sous-naines de type B

NASA Astrophysics Data System (ADS)

Charpinet, Stephane

L'objectif principal de cette thèse consiste à évaluer les possibilités que les étoiles sous naines de type B, aussi appelées sdB, puissent développer des variations de luminosité engendrées par des phénomènes de pulsations. Dans la mesure où, au commencement de cette étude, les sdB ne sont pas connues pour montrer ce type de comportement, notre approche s'effectue exclusivement sur des bases théoriques visant à déterminer, par le calcul, si ces étoiles ont le potentiel pour devenir instables. Le cas échéant, il s'agira d'évaluer quels sont les résultats susceptibles d'émerger d'un sondage de la structure interne de ces étoiles avec les méthodes de l'astéroséismologie. Après avoir introduit le contexte et les outils théoriques nécessaires à ce projet (théorie des pulsations stellaires et modèles d'étoiles sous-naines de type B), la démarche passe obligatoirement par une étude exhaustive des propriétés des modes de pulsation dans ces étoiles. Nous l'avons entreprise de manière systématique afin d'évaluer et de comprendre les comportements des oscillations en fonction des différents paramètres physiques qui caractérisent une sdB. Par souci de complétude, nous étudions également les rapports qu'entretiennent évolution et périodes de pulsation au cours de la phase sdB. Par la suite, fort des connaissances nouvellement acquises, nous nous lançons dans l'étude de la stabilité des modes d'oscillation, l'objectif étant d'identifier, le cas échéant, un mécanisme capable de déstabiliser, dans certaines conditions, une fraction de ces étoiles. Par cette approche, nous déterminons qu'un mécanisme κ associé à une région d'ionisation partielle de l'élément fer agit efficacement dans l'enveloppe des sdB si, toutefois, le fer y est présent en quantités extra- solaires. Nous montrons alors que des processus de diffusion, déjà fortement suspectes d'exister dans ces étoiles, sont en mesure d'accumuler des quantit

Crystallization and preliminary X-ray crystallographic analysis of the extracellular domain of LePRK2 from Lycopersicon esculentum.

PubMed

Xu, Anbi; Huang, Laiqiang

2014-02-01

The tomato (Lycopersicon esculentum) pollen-specific receptor kinase 2 (LePRK2) is a member of the large receptor-like kinase (RLK) family and is expressed specifically in mature pollen and pollen tubes in L. esculentum. Like other RLKs, LePRK2 contains a characteristic N-terminal leucine-rich repeat (LRR) extracellular domain, the primary function of which is in protein-protein interactions. The LePRK2 LRR is likely to bind candidate ligands from the external environment, leading to a signal transduction cascade required for successful pollination. LePRK2-LRR was purified using an insect-cell secretion expression system and was crystallized using the vapour-diffusion method. The crystals diffracted to a resolution of 2.50 Å and belonged to space group I4(1)22, with unit-cell parameters a = b = 93.94, c = 134.44 Å and one molecule per asymmetric unit.

Le conte: Mille et une facons de dire... (The Story: A Thousand and One Ways to Say...).

ERIC Educational Resources Information Center

Cazaux, Henri

1996-01-01

A teacher/storyteller recommends story creation by students to encourage creativity and pleasure in developing language skills. Suggested exercises include combining random nouns (e.g., "le fer et le bois") and creating a proverb about them, creating a story using names of consumer products, and developing a story using only body-language idioms…

Books reconsidered: Emile Durkheim, Le Suicide.

PubMed

Robertson, Michael

2006-12-01

To reappraise Emile Durkheim's taxonomy of suicide in Le Suicide in the light of recent experience. While Durkheim's scientific method and argument are fundamentally flawed, some of his concepts have instrumental value in attempting to understand the complex origins of suicidal behaviour. Durkheim's baseless dismissal of mental illness as a key determinant of suicidal behaviour weakens his thesis significantly. However, his conceptualization of anomic, egoistic and altruistic suicide provides a means of comprehending recent trends in suicidal behaviour in the former Soviet states and a possible window into the psyche of the suicides of religious and political extremists.

Restorative Justice Scripts in Ursula K. Le Guin's "Voices"

ERIC Educational Resources Information Center

Oziewicz, Marek C.

2011-01-01

This essay examines restorative justice scripting in "Voices", the second volume of Ursula K. Le Guin's "Annals of the Western Shore." Narrated by a rape-child, "Voices" is the story of an occupied city-state and of how the conquered and the conquerors negotiate a formula for peaceful coexistence. They are able to do…

Tested Demonstrations: Thermodynamic Changes, Kinetics, Equilibrium, and LeChatelier's Principle.

ERIC Educational Resources Information Center

Gilbert, George L., Ed.

1984-01-01

Procedures for demonstrating thermodynamic changes, kinetics and reaction mechanisms, equilibrium, and LeChatelier's principle are presented. The only materials needed for these demonstrations are beakers, water, assorted wooden blocks of varying thickness, assorted rubber tubing, and a sponge. The concepts illustrated in each demonstration are…

Humoral response against sialyl-Le(a) glycosylated protein species in esophageal cancer: Insights for immunoproteomic studies.

PubMed

Fernandes, Elisabete; Peixoto, Andreia; Neves, Manuel; Afonso, Luís Pedro; Santos, Lúcio Lara; Ferreira, José Alexandre

2015-12-01

Esophageal cancers (ECs) show poor prognosis and decreased overall survival due to late diagnosis and ineffective therapeutics, urging the introduction of novel biomarkers to aid disease management. The levels of sialyl-Lewis(a) antigen (sLe(a) ) are frequently increased in digestive tumours, which has been explored in serological non-invasive prognostication (CA19-9 test); however, with low sensitivity and specificity. Autoantibodies against cancer antigens are considered the next generation biomarkers, as they are present in circulation long before tumour-associated proteins. Based on these observations we have mined the serum of EC patients (n = 7) for antibodies against sLe(a) -glycosylated protein species. All EC were positive for sLe(a) , irrespectively of their histological nature but only two patients showed elevated CA19-9. Moreover, IgG titers, with emphasis on IgG1, were elevated in EC patients in comparison to the control group. SLe(a) -glycoproteins were then extracted from tumours of patients with negative CA19-9, isolated by immunoprecipitation and blotted with patients IgG. Autoantibodies against sLe(a) -glycosylated proteins were detected in all cases. Different SLe(a) -glycoproteins were observed for tumours of distinct histological natures, which now require identification and validation in larger patient sets. This preliminary data suggests that antoantibodies against sLe(a) glycosylated proteins hold potential for non-invasive diagnosis in CA19-9 negative cases and sets the rational for future immunoproteomic studies envisaging highly specific EC biomarkers. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

[Some remarks on the theory of sets by Richard Dedekind and Stanisław Leśniewski].

PubMed

Obojska, Lidia

2014-01-01

Mereology, is a part-whole theory, also called the theory of collective sets. It was founded in 1916 by Stanisław Leśniewski and this is an alternative theory versus the classical set theory by Georg Cantor. These two theories are usually teamed up together as Leśniewski himself was referring to the concept of the set by Cantor and Cantor is considered the "main" ideologist of the set theory. However, when analyzing the original texts of various authors, it seems that the very concept of a collective set is closer to the idea of Richard Dedekind rather than that of Georg Cantor. It is known that Cantor borrowed some concepts on the notion of set from Dedekind, whose ideas were also known to Leśniewski, however, there is no study on this topic. This work is therefore an attempt to compare some set-theoretical concepts of both of these authors, i.e. S. Leśiewski and R. Dedekind and the presentation of their convergence.

Antibakterielle In-vitro-Wirksamkeit ätherischer Öle gegen veterinärmedizinisch relevante Keime klinischer Isolate von Hunden, Katzen und Pferden.

PubMed

Bismarck, Doris; Schneider, Marianne; Müller, Elisabeth

Einleitung: Ätherische Öle sind die Grundlage der Aromatherapie. Unter anderem wird ihnen eine antibakterielle Wirkung zugeschrieben. In dieser Studie sollte die In-vitro-Wirksamkeit ätherischer Öle gegen ein breites Spektrum veterinärmedizinisch relevanter Erreger getestet werden. Methoden: Die antibakterielle Aktivität von 16 ätherischen Ölen wurde mittels Agardiffusionstest bestimmt. Getestet wurden grampositive und gramnegative Erreger, die aus klinischen Isolaten von Hunden, Katzen und Pferden aus der veterinärmedizinischen Routinediagnostik stammten. Die Einteilung der Wirksamkeit in nicht, gering-, mittel- und hochgradig wirksam erfolgte anhand der Größe der Hemmhofradien des Bakterienwachstums. Ergebnisse: Generell zeigten sich sowohl grampositive als auch gramnegative Erreger empfindlich gegen einige der getesteten ätherischen Öle. Nicht nur gegen Staphylokokken, sondern auch gegen Methicillin-resistente Stämme der Staphylokokken wiesen die ätherischen Öle in vitro eine nicht zu vernachlässigende Wirkung auf. Pasteurella multocida stellte sich als eher sensibler Keim heraus, während Pseudomonas aeruginosa als vollkommen resistenter Keim eine Ausnahme bildete. Teebaum-, Oregano-, und Bergbohnenkrautöl waren die potentesten Öle. Zusätzlich zeigten sich bei den grampositiven Erregern Lemongrasöl und bei den gramnegativen Erregern Thymianöl als gut wirksam. Schlussfolgerung: Ätherische Öle verfügen in vitro über eine antibakterielle Aktivität gegen klinische Isolate von Hunden, Katzen und Pferden. Diese Studie bietet eine Grundlage für die Anwendung ätherischer Öle in der Veterinärmedizin. Es zeichneten sich Tendenzen im Wirkspektrum einzelner ätherischer Öle bzw. im Grad der Wirksamkeit ätherischer Öle hinsichtlich einzelner Erregerspezies ab, allerdings lässt sich keine sichere Vorhersage über ihre Wirksamkeit gegen einen spezifischen Keim eines individuellen Patienten treffen. Deswegen sollte vor einer Therapie mit �

Le traitement chirurgical des fractures du cotyle: à propos de 22 cas

PubMed Central

Mahdane, Hicham; Elghazi, Amine; Shimi, Mohamed; Elibrahimi, Abdelhalim; Elmrini, Abdelmajid

2014-01-01

Vingt deux patients présentant une fracture incongruente de l'acétabulum ont été opérés et revues avec un recul moyen de 2 ans. Le but de cette étude est d'analyser les résultats fonctionnels et radiologiques des fractures de l'acétabulum après traitement chirurgical. La population était constituée de 17 hommes et 5 femmes, avec un âge moyen de 42,5 ans. Les fractures de l'acétabulum étaient répertoriées selon la classification de Judet et Letournel: 11 fractures de la paroi postérieure, une fracture de la colonne postérieure, six fractures transversales, quatre fractures transversales associées à une paroi postérieure, et une seule fracture de la colonne postérieure avec fracture de la paroi postérieure. Quatre patients présentaient des lésions associées du bassin, sept patients avaient une luxation postérieur de la hanche, deux une luxation centrale et deux avaient un traumatisme crânien associée. Deux voies d'abords ont été utilisées dans ce travail: la voie de Kocher Langenbeck (19 cas), et la voie de Dana Mears (4 cas). A partir du bilan radiologique initial (bassin face, ¾ alaire, ¾ obturateur et tomodensitomértie) on évaluer le déplacement, la congruence, tête/toit et tête/acétabulum ainsi que le degré de comminution. La qualité de réduction était évaluée selon les critères de Matta et les résultats fonctionnels selon la cotation de Merle D'Aubigné. Sur le Plan radiologique nous avons obtenu 56,52% de réduction anatomique, alors que sur le plan fonctionnel 78% patient avaient de bons et très bon résultats. Parmi les complications postopératoires, on a noté un seul cas d'infection cutanée superficielle, cinq ossifications héterotopiques. A distance un cas d'ostéonécrose aseptique de la tête fémorale et un cas de coxarthrose. PMID:25374628

Computer Assisted Instruction: The Game "Le Choc des Multinationales."

ERIC Educational Resources Information Center

Cramer, Hazel

"Le Choc de Multinationales" is a microcomputer game for students in an upper-level commercial French couse, to be played by two opponents, one of whom may be another student or the computer itself as a direct business competitor. The game's requirements for language use and knowledge of business and economics theory and principles are moderate,…

Decolonizing the Choctaws: Teaching LeAnne Howe's "Shell Shaker"

ERIC Educational Resources Information Center

Hollrah, Patrice

2004-01-01

"Shell Shaker" (2001) by LeAnne Howe (Choctaw) is a novel that gives students an opportunity to learn that the history and culture of the Choctaw Nation of Oklahoma are alive today. Winner of the Before Columbus Foundation American Book Award in 2002, the novel deals with two parallel stories that converge in the present, one about the eighteenth…

Homogeneous purification and characterization of LePGT1--a membrane-bound aromatic substrate prenyltransferase involved in secondary metabolism of Lithospermum erythrorhizon.

PubMed

Ohara, Kazuaki; Mito, Koji; Yazaki, Kazufumi

2013-06-01

Membrane-bound type prenyltransferases for aromatic substrates play crucial roles in the biosynthesis of various natural compounds. Lithospermum erythrorhizon p-hydroxybenzoate: geranyltransferase (LePGT1), which contains multiple transmembrane α-helices, is involved in the biosynthesis of a red naphthoquinone pigment, shikonin. Taking LePGT1 as a model membrane-bound aromatic substrate prenyltransferase, we utilized a baculovirus-Sf9 expression system to generate a high yield LePGT1 polypeptide, reaching ~ 1000-fold higher expression level compared with a yeast expression system. Efficient solubilization procedures and biochemical purification methods were developed to extract LePGT1 from the membrane fraction of Sf9 cells. As a result, 80 μg of LePGT1 was purified from 150 mL culture to almost homogeneity as judged by SDS/PAGE. Using purified LePGT1, enzymatic characterization, e.g. substrate specificity, divalent cation requirement and kinetic analysis, was done. In addition, inhibition experiments revealed that aromatic compounds having two phenolic hydroxyl groups effectively inhibited LePGT1 enzyme activity, suggesting a novel recognition mechanism for aromatic substrates. As the first example of solubilization and purification of this membrane-bound protein family, the methods established in this study will provide valuable information for the precise biochemical characterization of aromatic prenyltransferases as well as for crystallographic analysis of this novel enzyme family. © 2013 The Authors Journal compilation © 2013 FEBS.

Molecular cloning and expression analysis of jasmonic acid dependent but salicylic acid independent LeWRKY1.

PubMed

Lu, M; Wang, L F; Du, X H; Yu, Y K; Pan, J B; Nan, Z J; Han, J; Wang, W X; Zhang, Q Z; Sun, Q P

2015-11-30

Various plant genes can be activated or inhibited by phytohormones under conditions of biotic and abiotic stress, especially in response to jasmonic acid (JA) and salicylic acid (SA). Interactions between JA and SA may be synergistic or antagonistic, depending on the stress condition. In this study, we cloned a full-length cDNA (LeWRKY1, GenBank accession No. FJ654265) from Lycopersicon esculentum by rapid amplification of cDNA ends. Sequence analysis showed that this gene is a group II WRKY transcription factor. Analysis of LeWRKY1 mRNA expression in various tissues by qRT-PCR showed that the highest and lowest expression occurred in the leaves and stems, respectively. In addition, LeWRKY1 expression was induced by JA and Botrytis cinerea Pers., but not by SA.

Encyclopédie scientifique de l'universe: les étoiles - le système solaire.

NASA Astrophysics Data System (ADS)

This book is a revised, extended and updated edition of the volume published in 1979 (27.003.156).Contents: Première partie - le système solaire: 1. Astronomie des positions (J. Lévy). 2. Le système des constantes astronomiques; les données fondamentales (A. Bec-Borsenberger, F. Chollet). 3. Mécanique du système solaire (B. Morando). 4. Relief et structure des planètes telluriques et des satellites (A. Cazenave, P. Masson, P. Thomas). 5. Physique des atmosphères planétaires denses (D. Gautier, M. Combes,G. Moreels, J. P. Parisot, O. Tallagrand). 6. Les anneaux entourant les planètes (N. Borderies, A. Dollfus). 7. Les comètes et les météorites (A. Levasseur-Regourd). 8. L'environnement du Soleil et de la Terre (J.-L. Steinberg, J.-P. Bibring, A. Boischot, P. Couturier, R. Dumont, T. Encrenaz, P. Lamy).Deuxième partie - le Soleil et les bases de la physique stellaire: 9. Théorie des atmosphères du Soleil et des étoiles (R. Michard). 10. Physique de l'atmosphère solaire {non perturbée} (P. Mein). 11. Les centres actifs (J.-C. Hénoux, J.-C. Vial). 12. Éruptions solaires et phénomènes transitoires (J.-C. Hénoux, M. Pick, G. Trottet). 13. Le cycle solaire (J. Latour, P. Simon).Troisième partie - physique des étoiles: 14. Acquisition des données fondamentales (F. Spite). 15. Les étoiles doubles (R. Bouigue, P. Muller). 16. Les étoiles variables (M. Auvergne, A. Baglin, D. Ducatel, J.-M. Le Contel, J. C. Valtier). 17. Structure interne et évolution des étoiles (J.-P. Zahn). 18. Les familles physiques d'étoiles (G. Cayrel).

Developpement d'un montage simulant l'erosion par la pluie pour l'evaluation des revetements glaciophobes dans le domaine aerospatial

NASA Astrophysics Data System (ADS)

Tremblay, Sarah-Eve

Ce memoire presente le developpement d’un montage simulant l’erosion par la pluie afin d’effectuer l’evaluation de differents revetements glaciophobes dans le domaine aerospatial. Bien que plusieurs revetements presentent une bonne efficacite a reduire l’adherence et/ou l’accumulation de glace, ils ne repondent pas necessairement aux normes de resistance a l’erosion simulee par les gouttes de pluie les frappant a grande vitesse. Il n’existe qu’une installation en Amerique du Nord offrant un service d’essai qui evalue la resistance a l’erosion par la pluie suivant les normes aerospatiales. Etant l’unique institution pouvant faire la certification de peintures utilisees sur les avions en ce qui a trait a l’erosion par la pluie, ce service est donc difficile d’acces et couteux. Le laboratoire international des materiaux antigivre (LIMA) a developpe un essai plus rapide et moins couteux, facilitant ainsi le developpement de revetements glaciophobes devant resister a l’erosion par la pluie. Dans cette etude, le developpement du montage d’erosion par la pluie effectue au laboratoire des materiaux antigivre (LIMA) est presente. En particulier, des essais sur quatre (4) revetements dont la resistance a l’erosion est connue, et sur trois revetements industriels, ont ete effectues afin d’ajuster les differents parametres du montage comme la pression et la temperature de l’eau ainsi que la robustesse du montage. Ensuite, des essais de sensibilite et de reproductibilite des resultats ont egalement ete effectues pour fin de validation du montage et du protocole experimental. Pour ce faire, le montage de type jet d’eau developpe consiste principalement en une pompe a haute pression qui projette un jet d’eau continu passant par les orifices d’un disque tournant. Cette operation permet de generer une goutte de pluie simulee qui est projetee sur un echantillon de revetement statique. L’essai est base sur la norme standard ASTM (Liquid

Curtis E. LeMay: A Great Warrior

DTIC Science & Technology

1984-04-01

Continue On F& Veta . sid~ e Of necessary and Identify hr block number) - Roview, analysis and comparison of Curtis E.Lemay’s strategy ir Europe and the...000 AIR COMMAND AND STAFF COLLEGE STUDENT REPORT, . CURTIS E . LE-MAY A GREAT WARRIORi’ l MAVO IAN . ROBINSON 84,-2190 -AUG 1 0 1984 • "’insights into...tomorrow" E ,,=IL i ’,’ ....... -" -- 84 08 08 03 ~032 DISCLAIMER The views and conclusions expressed in this document are those of the author. They

Mucocèle appendiculaire: à propos d'un cas observé à Lubumbashi

PubMed Central

Wakunga, Eric; Mukuku, Olivier; Bugeme, Marcellin; Tshiband, Moïse; Kipili, Audifax; Mobambo, Pitchou; Arung, Willy; Wakunga, Warach

2014-01-01

La mucocèle appendiculaire est une entité pathologique rare, mais potentiellement dangereuse, elle se présente sous différentes formes cliniques. Nous rapportons ici un cas d'une patiente âgée de 49 ans sans antécédents chirurgicaux chez qui nous avons découvert d'une façon fortuite cette affection. La clinique était celle d'un syndrome appendiculaire aigu patent et elle révélait une masse dans la fosse iliaque droite. Les examens de laboratoire ont montré une hyperleucocytose et une vitesse de sédimentation augmentée. L’échographie a démontré une masse kystique péricaecal. La patiente a subi une appendicectomie avec cæcectomie partielle et la pièce opératoire appendiculaire mesurait 153 mm de longueur et 64 mm de diamètre. L'analyse anatomopathologique de celle-ci a confirmé le diagnostic de mucocèle appendiculaire sans cellules de malignité. Les suites opératoires ont été simples et la patiente est sortie au cinquième jour postopératoire. PMID:25368725

Ponction biopsies rénales dans le Service de Néphrologie de Fès: indications et résultats: à propos de 522 cas

PubMed Central

Mbarki, Houda; Belghiti, Khadija Alaoui; Harmouch, Taoufiq; Najdi, Adil; Arrayhani, Mohamed; Sqalli, Tarik

2016-01-01

L'apport de la ponction biopsie rénale (PBR) dans le diagnostic, le choix thérapeutique et l’évaluation pronostique des néphropathies est considérable. Aucune étude marocaine n'a évalué la pratique et l'apport de la PBR. Notre objectif est d’étudier les indications de la PBR, déterminer la fréquence des maladies rénales identifiées par PBR dans notre région et de faire une confrontation entre les données clinico-biologiques et le diagnostic historique. Notre étude menée entre Janvier 2009 et Décembre 2012, est rétrospective. Nous avons inclus tous les patients du service de Néphrologie du CHU Hassan II de Fès ayant bénéficié d'une biopsie de reins natifs. 522 PBR ont été réalisées. Nous avons exclu 8 biopsies devant le manque de renseignements et avons donc retenu 514. L’âge moyen des patients au moment de la PBR est de 39 ±17 ans (3-82 ans). Le sex ratio est de 0,9. Le syndrome néphrotique est le diagnostic clinique le plus fréquent à tous les âges (58,2%). Les néphropathies glomérulaires représentent 94,2% des maladies rénales diagnostiquées, leur distribution varie selon l’âge des patients. La PBR a confirmé le premier diagnostic suspecté cliniquement dans 40,65% des cas, alors qu'elle a révélé un diagnostic inattendu chez 22,5% d'entre eux. Le diagnostic syndromique permet d'orienter vers la maladie rénale la plus probable et de guider les thérapeutiques urgentes en attendant les résultats de la PBR. Mais il ne peut en aucun remplacer la PBR qui reste le gold standard. PMID:27583085

Le syndrome du canal d’Alcock ou névralgie pudendale : un diagnostic à ne pas méconnaître

PubMed Central

Ziouziou, Imad; Bennani, Hassan; Zizi, Mohamed; Karmouni, Tarik; Khader, Khalid El; Koutani, Abdellatif; Andaloussi, Ahmed Iben Attya

2013-01-01

Résumé Le syndrome du canal d’Alcock – ou névralgie pudendale – est lié à la compression chronique du nerf pudendal dans la fossette ischiorectale ou au niveau du ligament sacroépineux. Le diagnostic du syndrome d’Alcock est surtout clinique. Les examens complémentaires sont dominés par les explorations électrophysiologiques et le test de bloc anesthésique. Le diagnostic repose sur des critères bien précis, soit les critères de Nantes. La prise en charge doit être globale, comprenant un traitement médicamenteux, des infiltrations, des techniques de neuromodulation, et dans les cas graves ou résistants, un traitement chirurgical qui consiste à libérer le nerf pudendal. Les névralgies pudendales peuvent être rencontrées après traitement d’une incontinence urinaire d’effort par bande-lettes sous-urétrales (TVT). Ce syndrome motive des consultations en urologie, car la douleur intéresse le territoire du périnée et des organes génitaux. Des signes urinaires peuvent aussi accompagner cette douleur. Il est donc judicieux de connaître cette pathologie. PMID:23914265

Approches pour la reduction de l'impact de defaut dans le transport d'energie du parc eolien offshore via VSC-HVDC =

NASA Astrophysics Data System (ADS)

Benadja, Mounir

Dans ce travail est presente un systeme de generation d'energie d'un parc eolien offshore et un systeme de transport utilisant les stations VSC-HVDC connectees au reseau principal AC onshore. Trois configurations ont ete etudiees, modelisees et validees par simulation. Dans chacune des configurations, des contributions ameliorant les cotes techniques et economiques sont decrites ci-dessous : La premiere contribution concerne un nouvel algorithme MPPT (Maximum Power Point Tracking) utilise pour l'extraction de la puissance maximale disponible dans les eoliennes des parcs offshores. Cette technique d'extraction du MPPT ameliore le rendement energetique de la chaine de conversion des energies renouvelables notamment l'energie eolienne a petite et a grande echelles (parc eolien offshore) qui constitue un probleme pour les constructeurs qui se trouvent confrontes a developper des dispositifs MPPT simples, moins couteux, robustes, fiables et capable d'obtenir un rendement energetique maximal. La deuxieme contribution concerne la reduction de la taille, du cout et de l'impact des defauts electriques (AC et DC) dans le systeme construit pour transporter l'energie d'un parc eolien offshore (OWF) vers le reseau principal AC onshore via deux stations 3L-NPC VSCHVDC. La solution developpee utilise des observateurs non-lineaires bases sur le filtre de Kalman etendu (EKF). Ce filtre permet d'estimer la vitesse de rotation et la position du rotor de chacune des generatrices du parc eolien offshore et de la tension du bus DC de l'onduleur DC-AC offshore et des deux stations 3L-NPC-VSC-HVDC (offshore et onshore). De plus, ce developpement du filtre de Kalman etendu a permis de reduire l'impact des defauts AC et DC. Deux commandes ont ete utilisees, l'une (commande indirect dans le plan abc) avec EKF integre destinee pour controler le convertisseur DC-AC offshore et l'autre (commande d-q) avec EKF integre pour controler les convertisseurs des deux stations AC-DC et DC-AC tout en

Ethylene and cold participate in the regulation of LeCBF1 gene expression in postharvest tomato fruits.

PubMed

Zhao, Danying; Shen, Lin; Fan, Bei; Yu, Mengmeng; Zheng, Yang; Lv, Shengnan; Sheng, Jiping

2009-10-20

C-repeat/dehydration-responsive element binding factor (CBF) is a transcription factor regulating cold response in plants, of which little is known in fruits. We showed a double-peak expression pattern of Lycopersicon esculentum putative transcriptional activator CBF1 (LeCBF1) in mature green fruit. The peaks appeared at 2 and 16 h after subjection to cold storage (2 degrees C). The second peak was coincident with, and thus caused by a peak in endogenous ethylene production. We showed that LeCBF1 expression was regulated by exogenous ethylene and 1-methylcyclopropene, and was not expressed without cold induction. LeCBF1 expression was different in the five maturation stages of fruits, but expression peaked at 2 h at all stages.

Appel pour une allocation intelligente dans le financement du système de santé au Cameroun

PubMed Central

Sieleunou, Isidore

2011-01-01

Le Cameroun utilise un système de budgétisation historique et une approche «top-down» pour allouer ses ressources de santé publique. Cependant, le pays compte 175 districts de santé dont les fortes disparités de nature épidémiologique, économique, géographique et culturelle, devraient être prises en compte pour réduire les iniquités en matière de sante publique. Comment comprendre alors que dans ces conditions, le budget des administrations publiques alloué aux différents districts de santé au Cameroun soit quasi identique alors que les défis sont si différents? L'inefficience allocative (mauvaise attribution du budget) générée par un tel système conduit vraisemblablement à une inefficience technique (mauvaise utilisation du budget). Pour la marche vers l'atteinte des objectifs du millénaire en matière de sante, il est impératif et urgent que les décideurs du secteur de la santé allouent de manière intelligente les ressources dans le système de santé. PMID:22355420

Le Conte's sparrows breeding in Conservation Reserve Program fields: precipitation and patterns of population change

USGS Publications Warehouse

Igl, Lawrence D.; Johnson, Douglas H.

1999-01-01

The climate of the North American Great Plains is highly dynamic, with great year-to-year variability in precipitation and periodic, often extreme, wet and dry cycles (Bragg 1995). Drought is a major force of ecological disturbance on the Great Plains and has played a key role in directing the evolution of the grassland biota of this region (Knopf and Samson 1997). Although grassland birds may differ in their responses to enviromenental variations (Rotenberry and Wiens 1991), climatic variability and concomitant unpredictability of resources strongly influence populations of grassland birds across space and time (Wiens 1974, 1986; Cody 1985). Not surprisingly, breeding bird populations on the Great Plains are highly dynamic, exhibiting considerable annual variation in composition, abundance, and distribution (Johnson and Grier 1988, George et al. 1992, Zimmerman 1992, Igl and Johnson 1997). Recently, interest in grassland birds has increased with the recognition that many species are declining both continentally (Droege and Sauer 1994) and globally (Goriup 1988). Identification of the specific factors associated with grassland bird declines in North America, however, remains largely enigmatic (Herkert 1997), and it is complicated by the considerable annual fluctuations in grassland bird distribution and abundance (Igl and Johnson 1997). Although there is evidence that land-use changes on the breeding grounds may have contributed to grassland bird declines (e.g., Igl and Johnson 1997), there also is an indication that long-term drought conditions may have influenced recent population changes of some breeding birds on the Great Plains (Droege and Sauer 1989, Peterjohn and Sauer 1993, Bethke and Nudds 1995, Igl and Johnson 1997). Le Conte's Sparrow (Ammodramus leconteii) is a secretive grassland bird that breeds in central and southern Canada and the northcentral United States (Murray 1969). It winters primarily in the southern United States (Peterson 1980, 1990

Le Chatelier's Principle Applied to the Temperature Dependence of Solubility.

ERIC Educational Resources Information Center

Treptow, Richard S.

1984-01-01

One effect of temperature is its influence on solubility, and that effect is used as a common example when teaching Le Chatelier's principle. Attempts to clarify the question of whether the principle holds in the case of the solubility of ionic compounds in water by investigating the literature data in detail. (JN)

Geomorphic evolution of the Le Sueur River, Minnesota, USA, and implications for current sediment loading

USGS Publications Warehouse

Gran, K.B.; Belmont, P.; Day, S.S.; Jennings, C.; Johnson, Aaron H.; Perg, L.; Wilcock, P.R.

2009-01-01

There is clear evidence that the Minnesota River is the major sediment source for Lake Pepin and that the Le Sueur River is a major source to the Minnesota River. Turbidity levels are high enough to require management actions. We take advantage of the well-constrained Holocene history of the Le Sueur basin and use a combination of remote sensing, fi eld, and stream gauge observations to constrain the contributions of different sediment sources to the Le Sueur River. Understanding the type, location, and magnitude of sediment sources is essential for unraveling the Holocene development of the basin as well as for guiding management decisions about investments to reduce sediment loads. Rapid base-level fall at the outlet of the Le Sueur River 11,500 yr B.P. triggered up to 70 m of channel incision at the mouth. Slope-area analyses of river longitudinal profi les show that knickpoints have migrated 30-35 km upstream on all three major branches of the river, eroding 1.2-2.6 ?? 109 Mg of sediment from the lower valleys in the process. The knick zones separate the basin into an upper watershed, receiving sediment primarily from uplands and streambanks, and a lower, incised zone, which receives additional sediment from high bluffs and ravines. Stream gauges installed above and below knick zones show dramatic increases in sediment loading above that expected from increases in drainage area, indicating substantial inputs from bluffs and ravines.

Occurrence of dsRNA Mycovirus (LeV-FMRI0339) in the Edible Mushroom Lentinula edodes and Meiotic Stability of LeV-FMRI0339 among Monokaryotic Progeny

PubMed Central

Kim, Jung-Mi; Yun, Suk-Hyun; Park, Seung-Moon; Ko, Han-Gyu; Kim, Dae-Hyuk

2013-01-01

dsRNA was found in malformed cultures of Lentinula edodes strain FMRI0339, one of the three most popular sawdust cultivated commercial strains of shiitake, and was also found in healthy-looking fruiting bodies and actively growing mycelia. Cloning of the partial genome of the dsRNA revealed the presence of the RdRp sequence of a novel L. edodes mycovirus (LeV), and sequence comparison of the cloned amplicon showed identical sequences sequence to known RNA-dependent RNA polymerase genes of LeV found in strain HKA. The meiotic stability of dsRNA was examined by measuring the ratio of the presence of dsRNA among sexual monokaryotic progeny. More than 40% of the monokaryotic progeny still contained the dsRNA, indicating the persistence of dsRNA during sexual reproduction. Comparing the mycelia growth of monokaryotic progeny suggested that there appeared to be a tendency toward a lower frequency of virus incidence in actively growing progeny. PMID:25288977

The world of LeGoo assessed: a short systematic and critical review.

PubMed

Shalhoub, J; Hinchliffe, R J; Powell, J T

2013-01-01

It is very difficult to identify whether the use of the thermosensitive polymer LeGoo offers advantages over the use of clamps or clampless techniques for infra-inguinal bypass. This issue of the journal provides much additional information about the use of LeGoo. We have summarised all the available evidence. In a very heterogeneous patient population, with heterogeneous graft type and location, the primary technical success rate remains high at 90% [95%CI 83-99], the 3 months secondary graft patency is 71 [95%CI 58-84]% and limb salvage is 78% [95%CI 68-89]%. These promising early results need to be followed by extended follow up of the patients and standardised outcome reporting in the future. Copyright © 2012 European Society for Vascular Surgery. Published by Elsevier Ltd. All rights reserved.

Le syndrome néphrotique idiopathique (SNI) de l’enfant à Dakar: à propos de 40 cas

PubMed Central

Keita, Younoussa; Lemrabott, Ahmed Tall; Sylla, Assane; Niang, Babacar; Ka, El Hadji Fary; Dial, Chérif Mohamed; Ndongo, Aliou Abdoulaye; Sow, Amadou; Moreira, Claude; Niang, Abdou; Ndiaye, Ousmane; Diouf, Boucar; Sall, Mouhamadou Guélaye

2017-01-01

Introduction L’objectif de ce travail était d’analyser les caractéristiques diagnostiques, thérapeutiques et évolutives de l’enfant atteint de néphrose dans un service de pédiatrie de Dakar. Méthodes L’étude était réalisée au service de pédiatrie de l’hôpital Aristide Le Dantec. Il s’agissait d’une étude rétrospective sur une période de 03 ans allant du 1er janvier 2012 au 31 décembre 2014. Ont été inclus tous les patients âgés de 02 ans à 12 ans présentant un tableau de Syndrome néphrotique idiopathique. Résultats Quarante cas de néphrose étaient colligés soit une prévalence de 23% parmi les néphropathies prises en charge dans le service. L’âge moyen était de 7,11± 3,14 ans. Le syndrome néphrotique était pur chez 72,5% (n=29) des patients. Les œdèmes des membres inférieurs étaient présents chez 100% des patients, l’oligurie dans 55% (n=22) et l’HTA dans 5% (n=2) des cas. La protéinurie moyenne était de 145,05 ± 85,54 mg/kg/24heures. La protidémie moyenne était de 46,42 ±7,88 g/L et l’albuminémie moyenne de 17,90 ± 7,15 g/L. Trente-neuf patients avaient reçu une corticothérapie à base de prednisone. La corticosensibilité était retenue chez 77% (n=30) des patients et la corticorésistance chez 13% (n=5) des cas. Le facteur de mauvaise réponse à la corticothérapie était un niveau de protéinurie initiale supérieure à 150 mg/kg/jour (p = 0,024). La biopsie rénale était réalisée chez 18% (n=7) des patients et retrouvait dans 57,2% (n=4) des cas une hyalinose segmentaire et focale. Le cyclophosphamide et l’azathioprine étaient associés aux corticoïdes dans 10% (n=4) des cas chacun. Le taux de rémission globale était de 89,8%. L’évolution vers l’insuffisance rénale chronique était notée chez trois (03) des patients. Conclusion La néphrose représentait près du quart des néphropathies prises en charge dans notre service. Le taux de rémission globale était élevé. Le

Offset fémoral et le fonctionnement de la hanche dans la prothèse totale de la hanche

PubMed Central

Rachid, Abdelillah; Moncef, Erraji; Najib, Abbassi; Abdeljaouad, Najib; Abdelkarim, Daudi; Hicham, Yacoubi

2014-01-01

L'offset fémoral est l’élément pronostic le plus important dans l'arthroplastie de la hanche. Sa restauration est devenue de plus en plus une obligation. Toute modification de la valeur native de l'offset retenti sur la qualité du fonctionnement clinique de la hanche. Le but de notre travail était d’évaluer le fonctionnement clinique de la hanche en fonction de la valeur de l'offset fémoral après une arthroplastie. C'est une étude rétrospective effectuée entre 2010 et 2013, comportant 27 patients ayant bénéficiés d'une arthroplastie totale de la hanche. Les patients ayant eu un geste chirurgicale antérieur sur la même hanche ou sur la hanche controlatérale ont été exclus. Les mesures ont été effectuées sur des radiographies standards de la hanche en rotation interne d'environ 15°, avec un agrandissement à 100%. Les résultats cliniques étaient évalués au moyen du score de WOMAC qui était en moyenne de 15,2 points, et le score de Merle d'Aubigné-Postel avec une moyenne de 15 points. Deux autres tests ont été évalués dans notre étude qui sont le step et le hop test. Les meilleurs résultats fonctionnels ont été obtenus chez les patients ayant eu une latéralisation de la tige fémoral avec un offset augmenté. PMID:25400835

6. Historic American Buildings Survey, Pierre LeBoutillier and Trusten M. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

6. Historic American Buildings Survey, Pierre LeBoutillier and Trusten M. Baldwin, Photographers, April, 1960 NORTHWEST ROOM SHOWING COOK FIREPLACE, ORIGINAL MANTEL, CRANE AND OPENING FOR BAKE OVEN. - King of Prussia Inn, U.S. Route 202 (Upper Merion Township), King of Prussia, Montgomery County, PA

10. VIEW TOWARD PORT BOW IN THE FOC'S'LE OF THE ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

10. VIEW TOWARD PORT BOW IN THE FOC'S'LE OF THE EVELINA M. GOULART. OBJECT IN THE FOREGROUND IS A FOLDING MESS TABLE LOCATED BETWEEN THE TIERS OF BUNKS. - Auxiliary Fishing Schooner "Evelina M. Goulart", Essex Shipbuilding Museum, 66 Main Street, Essex, Essex County, MA

Developpement d'outils quantitatifs pour le suivi par imagerie TEP/TDM de la reponse a la chimiotherapie et de sa toxicite

NASA Astrophysics Data System (ADS)

Croteau, Etienne

L'objectif de ce projet de doctorat est de developper des outils quantitatifs pour le suivi des traitements de chimiotherapie pour le cancer du sein et de leurs effets cardiotoxiques a l'aide de l'imagerie TEP dynamique. L'analyse cinetique en TEP dynamique permet l'evaluation de parametres biologiques in vivo. Cette analyse peut etre utilise pour caracteriser la reponse tumorale a la chimiotherapie et les effets secondaires nefastes qui peuvent en resulter. Le premier article de cette these decrit la mise au point des techniques d'analyse cinetique qui utilisent la fonction d'entree d'un radiotraceur derive de l'image dynamique. Des corrections de contamination radioactive externe (epanchement) et de l'effet de volume partiel ont ete necessaires pour standardiser l'analyse cinetique et la rendre quantitative. Le deuxieme article porte sur l'evaluation d'un nouveau radiotraceur myocardique. Le 11C-acetoacetate, un nouveau radiotraceur base sur un corps cetonique, a ete compare au 11C-acetate, couramment utilise en imagerie cardiaque TEP. L'utilisation de 3H-acetate et 14C-acetoacetate ont permis d'elucider la cinetique de ces traceurs depuis la fonction d'entree et la captation par les mitochondries cardiaques qui reflete la consommation en oxygene, jusqu'a la liberation de leurs principaux metabolites reciproques (3H20 et 14CO2). Le troisieme et dernier article de cette these presente l'integration d'un modele qui evalue la reserve cardiaque de perfusion et de consommation en oxygene. Un modele de cardiomyopathie a ete etabli a l'aide d'un agent chimiotherapeutique contre le cancer du sein, la doxorubicine, reconnu comme etant cardiotoxique. Un protocole de repos/effort a permis d'evaluer la capacite d'augmentation de perfusion et de consommation en oxygene par le coeur. La demonstration d'une reserve cardiaque reduite caracterise la cardiotoxicite. La derniere contribution de cette these porte sur la mise au point de methodes peu invasives pour mesurer la

Le cannabis et les enfants et adolescents canadiens

PubMed Central

Grant, Christina N; Bélanger, Richard E

2017-01-01

Résumé L’usage du cannabis, la drogue illicite la plus consommée dans le monde, est fréquent chez les adolescents canadiens. La consommation de cannabis à l’adolescence peut provoquer des modifications fonctionnelles et structurelles du cerveau en développement et induire une atteinte cérébrale. Dans ce groupe d’âge, la consommation de marijuana s’associe fortement à la dépendance au cannabis et à d’autres troubles de l’usage d’une substance, à l’adoption et au maintien du tabagisme, à l’augmentation des troubles de santé mentale, y compris la dépression, l’anxiété et la psychose, à une perturbation du développement neurologique et à un déclin cognitif ainsi qu’à une diminution de la performance scolaire et des réalisations au cours de la vie. Le taux de soins médicaux aigus et d’hospitalisations chez les jeunes enfants qui ont consommé involontairement du cannabis est en hausse. Compte tenu du débat en cours sur la réglementation du cannabis au Canada, l’examen attentif des preuves de ses effets sur la santé et la mise en place de mécanismes de protection deviennent des priorités absolues en santé publique.

2010 Coalition Battle Management Language Workshop (Atelier 2010 sur le langage de gestion du champ de bataille pour les operations en coalition)

DTIC Science & Technology

2010-02-01

Feb 2010 2010 Coalition Battle Management Language Workshop (Atelier 2010 sur le langage de gestion du champ de bataille pour les opérations en...RTO MEETING PROCEEDINGS MP-MSG-079 2010 Coalition Battle Management Language Workshop (Atelier 2010 sur le langage de gestion du champ de ...RTO-MP-MSG-079 ES - 3 Atelier 2010 sur le langage de gestion du champ de bataille pour les opérations en coalition (RTO-MP-MSG-079

Effects of Le Fort I Osteotomy on the Nasopharyngeal Airway-6-Month Follow-Up.

PubMed

Almuzian, Mohammed; Almukhtar, Anas; Ju, Xiangyang; Al-Hiyali, Ali; Benington, Philip; Ayoub, Ashraf

2016-02-01

The literature discussing the impact of a single Le Fort I osteotomy on nasopharyngeal airways is limited. This study assessed the volumetric changes in the nasopharyngeal airway after a single Le Fort I osteotomy and explored the correlation between these changes and 3-dimensional surgical movements of the upper jaw. This retrospective study was conducted in 40 patients who had undergone a single Le Fort I (maxillary advancement with or without impaction) to correct Class III malocclusion with maxillary hypoplasia. Preoperative (T1) and 6-month postoperative (T2) cone-beam computed tomographic (CBCT) scans of these patients were used for analysis. Maxillary surgical movements and volumetric changes in the nasopharyngeal airway were measured. The reproducibility of the measurements was evaluated using paired t tests and intraclass correlation coefficients. The Wilcoxon test and Pearson correlation coefficient were applied to evaluate the volumetric changes in the nasopharyngeal airway space and assess the correlations of these changes to the maxillary surgical movements. Six patients were excluded from the study owing to major differences (>5°) in their head and neck posture between the T1 and T2 CBCT scans. The errors of the repeated measurements were insignificant (P > .05), with a high level of agreement (r = 0.99; P < .05) between the repeated digitization of the landmarks. There was a statistically significant impact of a Le Fort I osteotomy on the right maxillary sinus (decreased by 17.8%) and the lower retropalatal space (expanded by 17.3%; P < .05). The correlation between the change in airway volume and the magnitude of surgical maxillary movements was moderate (r = .4). Similarly, there was a moderate correlation between changes in the upper nasopharynx and those in the hypopharynx. The single Le Fort I osteotomy was found to increase the retroglossal airway volume. This could be important for the treatment of obstructive sleep apnea in patients with

Development of the Potassium-Argon Laser Experiment (KArLE) Instrument for In Situ Geochronology

NASA Technical Reports Server (NTRS)

Cohen, Barbara A.; Li, Z.-H.; Miller, J. S.; Brinckerhoff, W. B.; Clegg, S. M.; Mahaffy, P. R.; Swindle, T. D.; Wiens, R. C.

2012-01-01

Absolute dating of planetary samples is an essential tool to establish the chronology of geological events, including crystallization history, magmatic evolution, and alteration. Traditionally, geochronology has only been accomplishable on samples from dedicated sample return missions or meteorites. The capability for in situ geochronology is highly desired, because it will allow one-way planetary missions to perform dating of large numbers of samples. The success of an in situ geochronology package will not only yield data on absolute ages, but can also complement sample return missions by identifying the most interesting rocks to cache and/or return to Earth. In situ dating instruments have been proposed, but none have yet reached TRL 6 because the required high-resolution isotopic measurements are very challenging. Our team is now addressing this challenge by developing the Potassium (K) - Argon Laser Experiment (KArLE) under the NASA Planetary Instrument Definition and Development Program (PIDDP), building on previous work to develop a K-Ar in situ instrument [1]. KArLE uses a combination of several flight-proven components that enable accurate K-Ar isochron dating of planetary rocks. KArLE will ablate a rock sample, determine the K in the plasma state using laser-induced breakdown spectroscopy (LIBS), measure the liberated Ar using quadrupole mass spectrometry (QMS), and relate the two by the volume of the ablated pit using an optical method such as a vertical scanning interferometer (VSI). Our preliminary work indicates that the KArLE instrument will be capable of determining the age of several kinds of planetary samples to +/-100 Myr, sufficient to address a wide range of geochronology problems in planetary science.

PACD 2006

DTIC Science & Technology

2007-05-01

American Institute of Aeronautics and Astronautics 1 PACD 2006 Yves de Lassat de Pressigny * Centre d’Essais en Vol, FR Richard Benney† US...Army Natick Soldier Research, Development and Engineering Center Mick Vallance ‡ Joint Air Transportation Evaluation Unit, UK Jan-Henrik Wintgens

Information Manpower Forecasting. Papers Presented at the FID/ET Seminar (Espoo, Finland, August 24-27, 1988).

ERIC Educational Resources Information Center

Dosa, Marta L., Ed.; Froehlich, Thomas J., Ed.

This collection contains 20 papers written by educators, administrators and information scientists who had conducted manpower surveys in the library and information fields: (1) "Background and Evolution of Educational Planning and Forecasting for Information Manpower" (Yves Courrier); (2) "Indicators for the Emerging Information…

Tuberculose chez le personnel de santé du secteur public au Burundi: fréquence et facteurs de risque

PubMed Central

Mukuku, Olivier; Ruhindiza, Bienvenu Mukuku; Mupepe, Alexis Kumba; Sawadogo, Michel

2013-01-01

Introduction Le but de cette étude était de déterminer la fréquence de la tuberculose (TB) chez le personnel de santé du secteur public en charge des patients tuberculeux et d’évaluer les facteurs de risque de contracter la tuberculose chez ce personnel au Burundi. Méthodes Il s’agit d’une étude transversale à visée analytique réalisée auprès de 300 travailleurs prestant dans 30 centres de dépistage et de traitement de la TB (CDT) au Burundi du 16 octobre au 15 novembre 2012. Les paramètres sociodémographiques et professionnels ainsi que l’antécédent de vaccination BCG de travailleurs ayant été touché par la TB ont été analysé et comparé à ceux de travailleurs qui ne l’ont pas été. Le seuil de signification a été fixé à p < 0,05. Résultats La fréquence de la TB chez le personnel de santé est de 15%. Le risque de souffrir de la TB est de près de 4 fois chez les travailleurs âgés d’au moins 50 ans (OR=3,73; 1,53-9,08), chez ceux qui n’ont jamais reçu de vaccin de BCG (OR=3,73; 1,24-11,03), chez ceux qui n’ont pas de cicatrice vaccinale de BCG (OR=3,80; 1,67-8,62) et chez ceux qui travaillent depuis au moins 6 ans dans un CDT (OR=3,79; 1,44-9,96); ce risque est de 9 fois chez ceux qui sont mariés (OR=9,42; 1,26-70,23), de 8 fois chez ceux qui n’aèrent pas leurs salles de travail (OR=8,20; 1,48-48,23) et de 6 fois chez ceux qui ont comme profession nettoyeur ou aide-soignant (OR=6,12; 2,92-12,82). Par contre, aucune corrélation statistiquement significative n’a été observée entre le fait de souffrir de la TB et le sexe mais aussi le nombre d’heures de contact d’un travailleur avec un patient tuberculeux (p>0,05). Conclusion L’âge, l’antécédent de vaccination de BCG ainsi que la majorité de paramètres professionnels sont en association avec la maladie TB des travailleurs de CDT. D’où, la maîtrise de certains facteurs de risque s’avère important pour faire face au fardeau de la TB parmi

Les conseils des cliniciens canadiens en matière de commotion dans le sport sont-ils cohérents?

PubMed Central

Carson, James D.; Rendely, Alexandra; Garel, Alisha; Meaney, Christopher; Stoller, Jacqueline; Kaicker, Jatin; Hayden, Leigh; Moineddin, Rahim; Frémont, Pierre

2016-01-01

Résumé Objectif Comparer les connaissances et l’utilisation des recommandations concernant la prise en charge de la commotion dans le sport (CDS) démontrées par les spécialistes de la médecine du sport et de l’exercice (SMSE) et les urgentologues afin d’évaluer la réussite du transfert des connaissances sur la CDS au Canada. Conception Un sondage à choix multiples envoyé par courriel et autoadministré par des SMSE et des urgentologues. La validité du contenu du sondage a fait l’objet d’une évaluation. Contexte Canada. Participants Le sondage a été complété entre mai et juillet 2012 par des SMSE qui ont réussi l’examen menant au diplôme de l’Académie canadienne de la médecine du sport et de l’exercice et des urgentologues qui n’avaient pas ce diplôme. Principaux paramètres à l’étude La connaissance et l’identification des sources d’information sur la prise en charge des commotions, l’utilisation des stratégies de diagnostic de la commotion et l’utilisation d’une terminologie courante et cohérente dans l’explication des stratégies de repos aux patients après une CDS. Résultats Le taux de réponse était de 28 % (305 sur 1085). Les taux de réponse par les SMSE et les urgentologues se situaient respectivement à 41 % (147 sur 360) et 22 % (158 sur 725). Parmi les répondants, 41 % des urgentologues et 3 % des SMSE n’étaient pas au courant de l’existence de déclarations consensuelles sur la commotion dans le sport; 74 % des SMSE utilisaient « habituellement ou toujours » la version 2 de l’Outil d’évaluation de la commotion dans le sport (SCAT2), tandis que 88 % des urgentologues n’utilisaient jamais le SCAT2. Aucune réponse uniforme n’a été documentée à la question visant à connaître les meilleurs modes de repos cognitif. Conclusion Nous avons cerné des différences et un manque d’uniformité chez les SMSE et les urgentologues dans la mise en application des recommandations

Taxonomic synopsis of invasive and native Spartina (Poaceae, Chloridoideae) in the Pacific Northwest (British Columbia, Washington and Oregon), including the first report of Spartina ×townsendii for British Columbia, Canada

PubMed Central

Saarela, Jeffery M.

2012-01-01

Abstract Five species of the grass genus Spartina are invading salt marshes along the Pacific coast of North America, of which three have been documented in British Columbia, Canada, in only the last decade. A taxonomic synopsis of the two native (Spartina gracilis, Spartina pectinata) and five introduced Spartina taxa (Spartina anglica, Spartina alterniflora, Spartina densiflora, Spartina patens, Spartina ×townsendii) in the Pacific Northwest is presented to facilitate their identification, including nomenclature, a new taxonomic key, new descriptions for a subset of taxa, and representative specimens. Spartina ×townsendii is newly reported for the flora of British Columbia. The non-coastal species Spartina pectinata is reported from an urban site in British Columbia, the first confirmed report of the taxon for the province. Lectotypes are newly designated for Spartina anglica C.E. Hubb., Spartina maritima subvar. fallax St.-Yves, and Spartina cynosuroides f. major St.-Yves. PMID:22461730

LE[superscript 3]AD Academy Builds Professionalism in Vocational Students

ERIC Educational Resources Information Center

Hall, Candace

2012-01-01

Principal David Wheeler of Southeastern Regional Vocational-Technical High School founded LE[superscript 3]AD Academy--an innovative program that gives students the opportunity to build and run their own town in teams and with guidance from teachers. The program started in the spring of 2011, and it is innovative in many ways. The students' main…

Lentiviral gene ontology (LeGO) vectors equipped with novel drug-selectable fluorescent proteins: new building blocks for cell marking and multi-gene analysis.

PubMed

Weber, K; Mock, U; Petrowitz, B; Bartsch, U; Fehse, B

2010-04-01

Vector-encoded fluorescent proteins (FPs) facilitate unambiguous identification or sorting of gene-modified cells by fluorescence-activated cell sorting (FACS). Exploiting this feature, we have recently developed lentiviral gene ontology (LeGO) vectors (www.LentiGO-Vectors.de) for multi-gene analysis in different target cells. In this study, we extend the LeGO principle by introducing 10 different drug-selectable FPs created by fusing one of the five selection marker (protecting against blasticidin, hygromycin, neomycin, puromycin and zeocin) and one of the five FP genes (Cerulean, eGFP, Venus, dTomato and mCherry). All tested fusion proteins allowed both fluorescence-mediated detection and drug-mediated selection of LeGO-transduced cells. Newly generated codon-optimized hygromycin- and neomycin-resistance genes showed improved expression as compared with their ancestors. New LeGO constructs were produced at titers >10(6) per ml (for non-concentrated supernatants). We show efficient combinatorial marking and selection of various cells, including mesenchymal stem cells, simultaneously transduced with different LeGO constructs. Inclusion of the cytomegalovirus early enhancer/chicken beta-actin promoter into LeGO vectors facilitated robust transgene expression in and selection of neural stem cells and their differentiated progeny. We suppose that the new drug-selectable markers combining advantages of FACS and drug selection are well suited for numerous applications and vector systems. Their inclusion into LeGO vectors opens new possibilities for (stem) cell tracking and functional multi-gene analysis.

The NASA LeRC regenerative fuel cell system testbed program for goverment and commercial applications

NASA Astrophysics Data System (ADS)

Maloney, Thomas M.; Prokopius, Paul R.; Voecks, Gerald E.

1995-01-01

The Electrochemical Technology Branch of the NASA Lewis Research Center (LeRC) has initiated a program to develop a renewable energy system testbed to evaluate, characterize, and demonstrate fully integrated regenerative fuel cell (RFC) system for space, military, and commercial applications. A multi-agency management team, led by NASA LeRC, is implementing the program through a unique international coalition which encompasses both government and industry participants. This open-ended teaming strategy optimizes the development for space, military, and commercial RFC system technologies. Program activities to date include system design and analysis, and reactant storage sub-system design, with a major emphasis centered upon testbed fabrication and installation and testing of two key RFC system components, namely, the fuel cells and electrolyzers. Construction of the LeRC 25 kW RFC system testbed at the NASA-Jet Propulsion Labortory (JPL) facility at Edwards Air Force Base (EAFB) is nearly complete and some sub-system components have already been installed. Furthermore, planning for the first commercial RFC system demonstration is underway.

Le Chatelier's principle with multiple relaxation channels

NASA Astrophysics Data System (ADS)

Gilmore, R.; Levine, R. D.

1986-05-01

Le Chatelier's principle is discussed within the constrained variational approach to thermodynamics. The formulation is general enough to encompass systems not in thermal (or chemical) equilibrium. Particular attention is given to systems with multiple constraints which can be relaxed. The moderation of the initial perturbation increases as additional constraints are removed. This result is studied in particular when the (coupled) relaxation channels have widely different time scales. A series of inequalities is derived which describes the successive moderation as each successive relaxation channel opens up. These inequalities are interpreted within the metric-geometry representation of thermodynamics.

Muon pair production at 52 GeV le radical s le 57 GeV using the AMY Detector at TRISTAN

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bacala, A.M.

1989-01-01

The reaction e{sup +}e{sup {minus}} {yields} {mu}{sup +}{mu}{sup {minus}} has been observed by the AMY Detector at 52 GeV {le} {radical}s {le} 57 GeV at the TRISTAN storage ring in Tsukuba, Japan. With an integrated luminosity of 18.6 pb{sup {minus}1}, this presents a new test of the standard model of the electroweak interactions in this previously unexplored energy region. The forward-backward charge asymmetry and the cross-section calculated at the various energies show agreement with the standard model predictions. The products of the vector and the axial-vector coupling constants of the electron and muon extracted from these measurements are also consistentmore » with theory. The data were combined at the average energy of {radical}s = 55.2 GeV. The measured asymmetry and cross-section are -34.4 {+-} 7.7% and 29.7 {+-} 2.1 pb respectively. This is in agreement with the standard model prediction of -28.3% for the asymmetry and 29.5 pb for the cross-section. The product of the axial couplings, g{sup e}{sub A}g{sup {mu}}{sub A} = 0.29 {+-} 0.07, and the product of the vector couplings, g{sup e}{sub V}g{sup {mu}}{sub V} = 0.01 {+-} 0.06, agree with the standard model predictions of 0.25 and .002 for these respective constants.« less

Le Fort III Distraction With Internal vs External Distractors: A Cephalometric Analysis.

PubMed

Robertson, Kevin J; Mendez, Bernardino M; Bruce, William J; McDonnell, Brendan D; Chiodo, Michael V; Patel, Parit A

2018-05-01

This study compares the change in midface position following Le Fort III advancement using either rigid external distraction (group 1) or internal distraction (group 2). We hypothesized that, with reference to right-facing cephalometry, internal distraction would result in increased clockwise rotation and inferior displacement of the midface. Le Fort III osteotomies and standardized distraction protocols were performed on 10 cadaveric specimens per group. Right-facing lateral cephalograms were traced and compared across time points to determine change in position at points orbitale, anterior nasal spine (ANS), A-point, and angle ANB. Institutional. Twenty cadaveric head specimens. Standard subcranial Le Fort III osteotomies were performed from a coronal approach and adequately mobilized. The specified distraction mechanism was applied and advanced by 15 mm. Changes of position were calculated at various skeletal landmarks: orbitale, ANS, A-point, and ANB. Group 1 demonstrated relatively uniform x-axis advancement with minimal inferior repositioning at the A-point, ANS, and orbitale. Group 2 demonstrated marked variation in x-axis advancement among the 3 points, along with a significant inferior repositioning and clockwise rotation of the midface ( P < .0001). External distraction resulted in more uniform advancement of the midface, whereas internal distraction resulted in greater clockwise rotation and inferior displacement. External distraction appears to provide increased vector control of the midface, which is important in creating a customized distraction plan based on the patient's individual occlusal and skeletal needs.

LeERF-1, a novel AP2/ERF family gene within the B3 subcluster, is down-regulated by light signals in Lithospermum erythrorhizon.

PubMed

Zhang, W; Zou, A; Miao, J; Yin, Y; Tian, R; Pang, Y; Yang, R; Qi, J; Yang, Y

2011-03-01

We previously showed that ethylene might be involved in the process of shikonin biosynthesis regulated by light signals. Here, we cloned a full-length cDNA of LeERF-1, a putative ethylene response factor gene, from Lithospermum erythrorhizon using the RACE (rapid amplification of cDNA ends) method. Phylogenetic analysis revealed that LeERF-1 was classified in the B3 subfamily, together with ERF1 and ORA59 of Arabidopsis. Heterologous expression of LeERF-1 in Arabidopsis showed that LeERF-1:eGFP fusion protein was precisely localised to the nucleus, implying that it might function as a transcription factor. Detailed expression analysis with real-time PCR showed that LeERF-1 was significantly down-regulated by white, blue and red light, although the inhibitory effect of red light was relatively weak compared to other light conditions. Tissue-specific expression analysis also indicated that LeERF-1 was dominantly expressed in the roots, which grow in soil in darkness. These patterns are all consistent with the effects of different light signals on regulating formation of shikonin and its derivatives, indicating that LeERF-1 might be a crucial positive regulator, like other B3 subfamily proteins (such as ORCA3 and ORA59), in regulating biosynthesis of secondary metabolites. © 2010 German Botanical Society and The Royal Botanical Society of the Netherlands.

Long-term follow-up after LeFort colpocleisis: patient satisfaction, regret rate, and pelvic symptoms.

PubMed

Song, Xiaochen; Zhu, Lan; Ding, Jing; Xu, Tao; Lang, Jinghe

2016-06-01

The aim of the study was to evaluate long-term patient satisfaction, regret rate, and pelvic symptoms in older women who underwent LeFort colpocleisis. A retrospective cohort study of women who underwent LeFort colpocleisis at least 3 years before was conducted. Records were reviewed for participant characteristics, comorbid conditions, and complications. The Patient Global Impression of Change (PGI-C) questionnaire and the Chinese version of the Pelvic Floor Distress Inventory-short form 20 (PFDI-20) were used to evaluate self-perceived quality of life. Regret was assessed by one additional question: "Do you regret choosing to have vaginal closure surgery for prolapse (Yes/No)?" LeFort colpocleisis accounted for 7.3% (42/572) of all the prolapse surgeries. Thirty-five of the women (83.3%) who responded were considered for statistical evaluation. Twenty-nine (82.9%) had at least one comorbid condition. After a median 5-year (range 3-7) follow-up period, no woman had experienced prolapse recurrence requiring a second surgery. No woman regretted having had the surgery. The satisfaction rate was 94.3%, with postoperative overactive bladder syndrome accounting for one "neither satisfied nor dissatisfied" woman and vaginal hematoma for another. Pelvic symptoms improved significantly from baseline (PFDI-20, preoperative 60.5 ± 29.5) to postoperative (14.1 ± 20.0, P < 0.001). After long-term follow-up, LeFort colpocleisis still had a high satisfaction rate, a low regret rate, and a positive impact on pelvic symptoms.

Le diverticule de l'urètre féminin: à propos de 18 cas

PubMed Central

Statoua, Mouad; El Ghanmi, Jihad; Karmouni, Tarik; El Khader, Khalid; Koutani, Abdellatif; Attya, Ahmed Iben

2014-01-01

Le diverticule de l'urètre ou poche sous urétrale est une affection rare, d’étiopathogénie non clairement établie, le diagnostique est clinique confirmé par l'urétrocystographie et le traitement est principalement chirurgicale consistant en une diverticulectomie par voie transvaginale. Nous rapportons l'expérience de notre service dans la prise en charge de cette affection en présentons une étude rétrospective sur une durée de 14 ans (entre 2000 et 2014) où on a pris en charge 18 patientes qui présentait un diverticule de l'urètre, l’âge moyen était de 36 ans, une symptomatologie urinaire ramenait les patientes à consulter où le diagnostic de DU a été posé par examen clinique confirmé en précisant ses caractéristiques en urétrocystographie, la prise en charge était chirurgicale et consistait en une diverticulectomie par voie transvaginale. Les suites post-opératoire était simples, la sonde vésicale retirée en moyenne 5,8 jours après l'intervention, on n'a noté aucune complication chez toute nos patientes, hormis un cas de récidives repris. Devant des troubles mictionnels récidivants de la femme, il est indispensable de rechercher un diverticule uréthral à l'examen clinique. La diverticulectomie transvaginale est l'intervention de choix offrant les meilleurs résultats. PMID:25400845

Immunogenicity and efficacy of a bivalent DNA vaccine containing LeIF and TSA genes against murine cutaneous leishmaniasis.

PubMed

Maspi, Nahid; Ghaffarifar, Fatemeh; Sharifi, Zohreh; Dalimi, Abdolhossein; Dayer, Mohammad Saaid

2017-03-01

There is no effective vaccine for the prevention and elimination of leishmaniasis. For this reason, we assessed the protective effects of DNA vaccines containing LeIF, TSA genes alone, or LeIF-TSA fusion against cutaneous leishmaniasis pEGFP-N1 plasmid (empty vector) and phosphate buffer saline (PBS) were used as control groups. Therefore, cellular and humoral immune responses were evaluated before and after the challenge with Leishmania major. Lesion diameter was also measured 3-12 weeks after challenge. All immunized mice with plasmid DNA encoding Leishmania antigens induced the partial immunity characterized by increased IFN-γ and IgG2a levels compared with control groups (p < 0.001). Furthermore, the immunized mice showed significant reduction in mean lesion sizes compared with mice in empty vector and PBS groups (p < 0.05). The reduction in lesion diameter was 29.3%, 34.1%, and 46.2% less in groups vaccinated with LeIF, TSA, and LeIF-TSA, respectively, than in PBS group at 12th week post infection. IFN/IL-4 and IgG2a/IgG1 ratios indicated that group receiving LeIF-TSA fusion had the highest IFN-γ and IgG2a levels. In this study, DNA immunization promoted Th1 immune response characterized by higher IFN-γ and IgG2a levels and also reduction in lesion size. These results showed that a bivalent vaccine containing two distinct antigens may induce more potent immune responses against leishmaniasis. © 2017 APMIS. Published by John Wiley & Sons Ltd.

Pour Une Poesie Chretienne a L'age Baroque: Mysticisme, Heroisme et Feminisme Chez Pierre Le Moyne 1602-1671

ERIC Educational Resources Information Center

Fares, Laila

2012-01-01

The study constituting the object of this research on one of the best French poets of the 17th century, yet one of the least known, Pierre Le Moyne, aims at restoring this great French poet in his right place, preparing and clearing the way in order to allow further research and stimulate future interest in his works. Pierre Le Moyne is not only…

Dermatomyosite du sujet âgé: étude de 4 observations dans le sud tunisien

PubMed Central

Frikha, Faten; Snoussi, Mouna; Salah, Raida Ben; Saidi, Noura; Kaddour, Neila; Bahloul, Zouhir

2012-01-01

La dermatomyosite (DM) touche essentiellement l’adolescent et l’adulte jeune, elle est très rare chez le sujet âgé, le plus souvent associée à des complications iatrogènes et à une pathologie cancéreuse. Nous avons étudié les caractéristiques de la DM du sujet âgé à travers une étude rétrospective dans laquelle nous avons comparé 4 patients âgés de plus de 65 ans au début de la myosite avec 40 sujets jeunes. PMID:23308331

List processing software for the LeCroy 1821 Segment Manager Interface

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dorries, T.; Moore, C.; Pordes, R.

1987-05-01

Many experiments at Fermilab now include some FASTBUS electronics in their data readout. The software reported in this paper provides general support for the LeCroy 1821 interface. The list processing device drivers allow FASTBUS data to be read out efficiently into the Fermilab Computing Department supported data acquisition systems.

News from Front (of the Solar System): the problem with Mercury, the Vulcan hypothesis, and General Relativity's first astronomical triumph

NASA Astrophysics Data System (ADS)

Sheehan, William

2016-01-01

The discovery of the outer planet Neptune in 1846, based on the calculated position published by Urbain Jean Joseph Le Verrier, has been hailed as the "zenith of Newtonian mechanics." An attempt by Le Verrier to further extend the dominion of Newton's gravitational theory to the innermost known planet of the Solar System, Mercury, seemingly came to grief with the discovery of a small unexplained discrepancy in the precession of the perihelion of Mercury, whose value was later calculated as 43".0 per century. Le Verrier proposed that it could be explained on the basis of Newtonian theory by assuming the existence of an intra-mercurial planet ("Vulcan") or ring of debris. Efforts to confirm this hypothesis, culminating in high drama on the plains of the western United States at the great North American solar eclipse of July 1878, proved futile; by 1908, W. W. Campbell and C.D. Perrine of Lick Observatory, who had carried out exhaustive photographic searches at three eclipses (1901, 1905, and 1908) could declare that Vulcan did not exist. The theoretical problem it was invoked to explain remained until November 1915, when Albert Einstein used the recently discovered generally covariant gravitational equations to put the problem to rest. "Perihelion motions explained quantitatively … you will be astonished," he wrote to his friend Michael Besso.

Expression of the le Mutation in Young Ovaries of Pisum sativum and Its Effect on Fruit Development.

PubMed Central

Santes, C. M.; Hedden, P.; Sponsel, V. M.; Reid, J. B.; Garcia-Martinez, J. L.

1993-01-01

The effect of the le mutation on the growth and gibberellin (GA) content of developing fruits was investigated using the near-isogenic lines of Pisum sativum L. 205+ (LeLe) and 205- (lele). Although stem elongation is known to be reduced in 205- plants by approximately 65%, the growth of pods and seeds was unaffected by the le mutation. GA1, GA3, and GA20 stimulated parthenocarpic development of unpollinated ovaries on both 205+ and 205- plants. GA20 was less active on 205- ovaries than on 205+, whereas GA1 had similar, high activity in both lines. The activity of GA3 was even higher than that of GA1 in both lines. Decapitation of 205+ plants induced parthenocarpic development of unpollinated ovaries, but this treatment was much less effective on 205- plants. The contents of GA1 and GA8 in entire ovaries 6 d after anthesis, as well as in the pod and fertilized ovules, were substantially lower in 205- than in 205+ plants, whereas the reverse was true for the levels of GA20 and GA29. These results suggest that 3[beta]-hydroxylation of GA20 to GA1 is reduced in ovaries as well as in vegetative tissues. Thus, the le mutation appears to be expressed in young reproductive organs of the 205- line, even though it does not affect the fruit phenotype. Because the content of GA3 in the ovary was similar in the two lines, one explanation for the normal fruit size in the 205- line is that GA3 is the native regulator of pod growth. Alternatively, sufficient GA1 may still be produced in 205- fruits to maintain normal pod growth. PMID:12231727

A Novel Dark-Inducible Protein, LeDI-2, and Its Involvement in Root-Specific Secondary Metabolism in Lithospermum erythrorhizon1

PubMed Central

Yazaki, Kazufumi; Matsuoka, Hideaki; Shimomura, Koichiro; Bechthold, Andreas; Sato, Fumihiko

2001-01-01

Lithospermum erythrorhizon produces red naphthoquinone pigments that are shikonin derivatives. They are accumulated exclusively in the roots of this plant. The biosynthesis of shikonin is strongly inhibited by light, even though other environmental conditions are optimized. Thus, L. erythrorhizon dark-inducible genes (LeDIs) were isolated to investigate the regulatory mechanism of shikonin biosynthesis. LeDI-2, showing the strict dark-specific expression, was further characterized by use of cell suspension cultures and hairy root cultures as model systems. Its mRNA accumulation showed a similar pattern with that of shikonin. In the intact plants LeDI-2 expression was observed solely in the root, and the longitudinal distribution of its mRNA was also in accordance to that of shikonin. LeDI-2 encoded a very hydrophobic polypeptide of 114 amino acids that shared significant similarities with some root-specific polypeptides such as ZRP3 (maize) and RcC3 (rice). Reduction of LeDI-2 expression by its antisense DNA in hairy roots of L. erythrorhizon decreased the shikonin accumulation, whereas other biosynthetic enzymes, e.g. p-hydroxybenzoic acid:geranyltransferase, which catalyzed a critical biosynthetic step, showed similar activity as the wild-type clone. This is the first report of the gene that is involved in production of secondary metabolites without affecting biosynthetic enzyme activities. PMID:11299363

Le carcinome neuro-endocrine cutané primitif: à propos d'un nouveau cas et revue de la littérature

PubMed Central

Boukind, Samira; Elatiqi, Oumkeltoum; Dlimi, Meriem; Elamrani, Driss; Benchamkha, Yassine; Ettalbi, Saloua

2015-01-01

Le carcinome neuro- endocrine cutané primitif (CNEC) est une tumeur cutanée rare et agressive du sujet âgé, favorisée par le soleil et l'immunodépression. Elle est caractérisée par une évolution agressive avec un fort taux de récidive, une évolution ganglionnaire régionale et un risque de métastases à distance. Nous rapportons un cas de cette tumeur chez un patient âgé de 67 ans sous forme d'un placard nodulaire hémorragique mesurant 16 /14 cm. Le patient a bénéficié d'une exérèse chirurgicale large avec couverture de la perte de substance par un lambeau musculo-cutané du muscle grand dorsal, un curage ganglionnaire axillaire et une radiothérapie adjuvante. Après un recul de 2 ans et 2 mois, le patient est toujours vivant sans métastase ni récidive. La littérature étant pauvre, la prise en charge diagnostique et thérapeutique est controversée et donc hétérogène. Globalement le pronostic est mauvais, et certains paramètres corrélés au pronostic sont précisés. PMID:26185585

Through Ecofeminist Eyes: Le Guin's "The Ones Who Walk Away from Omelas"

ERIC Educational Resources Information Center

Bennett, Barbara

2005-01-01

Barbara Bennett explains the tenets behind ecofeminism and why it is a useful and appropriate method of literary analysis for today's world. By applying the theory to Le Guin's story, she helps her students relate the issues of ecofeminism to their American lifestyle.

Le rôle médiateur du fonctionnement familial dans la relation entre l’adversité familiale et l’adaptation sociale des enfants d’âge préscolaire1

PubMed Central

Felli, M. C.; Parent, S.; Zelazo, P. D.; Tremblay, R. E.; Séguin, J. R.

2017-01-01

Résumé À la petite enfance, l’adaptation sociale de l’enfant dépend en partie des risques auxquels il est exposé dans son environnement. Toutefois, les mécanismes par lesquels les facteurs de risque opèrent leurs influences sur l’adaptation sociale de l’enfant sont peu documentés. Ainsi, cette étude examine dans un premier temps l’effet principal de l’adversité familiale, un cumul de facteurs de risque, sur les problèmes de comportement intériorisés et extériorisés, ainsi que sur la sécurité d’attachement des enfants d’âge préscolaire. Dans un deuxième temps, elle évalue le rôle médiateur du fonctionnement familial dans le lien entre l’adversité familiale et les problèmes de comportement de même qu’entre l’adversité familiale et la sécurité d’attachement des enfants d’âge préscolaire. Les 572 participants à l’étude (n=572) sont âgés entre cinq et 42 mois lors des mesures de l’adversité familiale et de 42 mois lors de la mesure des problèmes de comportement et du fonctionnement familial. Quatre-vingt d’entre eux (n=80) ont fait l’objet d’une mesure de sécurité d’attachement à 48 mois. Les résultats indiquent, d’abord, un effet principal de l’adversité familiale sur les problèmes de comportement intériorisés et extériorisés. Un effet médiateur significatif du fonctionnement familial est ensuite rapporté dans le lien entre l’adversité familiale et les problèmes de comportement intériorisés et extériorisés. Aucun effet significatif n’est observé pour la sécurité d’attachement des enfants de 48 mois. PMID:28567062

Isolation, characterization, and expression of Le-msx, a maternally expressed member of the msx gene family from the glossiphoniid leech, Helobdella.

PubMed

Master, V A; Kourakis, M J; Martindale, M Q

1996-12-01

The msx gene family is one of the most highly conserved of the nonclustered homeobox-containing genes. We have isolated an msx homolog (Le-msx) from the glossiphoniid leech, Helobdella robusta, and characterized its pattern of expression by whole mount in situ hybridization. In situ expression and reverse transcription polymerase chain reaction (RT-PCR) data results show that Le-msx is a maternal transcript initially uniformly distributed in the cortex of immature oocytes that becomes asymmetrically localized to the polar regions of the uncleaved zygote. This is the earliest reported expression for the msx gene family and the first maternally expressed homeodomain-containing transcription factor reported in annelids. During embryonic development, Le-msx is expressed in all 10 embryonic stem cells and their segmental founder cell descendants. At midembryonic stages, Le-msx is expressed in the expanding germinal plate. Le-msx is confined to the central nervous system and nephridia at late (stage 9) stages and subsequently disappears from nephridia. In addition, we present a phylogenetic hypothesis for the evolution of the msx gene family, including the identification of a putative C. elegans msx homolog and the realignment of the sponge msx homolog to the NK class of homeodomain genes.

Le Pseudomonas: Experience du Centre des Brules D’Annaba et Revue de la Litterature

PubMed Central

Chaibdraa, A.; Medjellekh, M.S.; Saouli, A.; Bentakouk, M.C.

2008-01-01

Summary Le Pseudomonasest un agent pathogène à l'origine d'infections nosocomiales graves dans les centres des brûlés. Son opportunisme et sa virulence en font une préoccupation majeure. Ce travail se propose d'évaluer la place de cette bactérie dans l'écologie bactérienne locale et d'en apprécier la sensibilité aux antibiotiques. Cette étude rétrospective préliminaire porte sur la période de juin 2003 à décembre 2005. Elle intéresse l'ensemble des prélèvements bactériologiques ayant pu être réalisés au centre des brûlés d'Annaba. L'effectif est de 633 micro-organismes isolés dont 128 Pseudomonas (20,2%): 127 aeruginosa (99,2%), 1 fluorescens (0,8%); distribution selon le site de prélèvement: écouvillon (87,5%), prélèvement trachéobronchique (4,6%), hémoculture (3,1%), cathéters (1,6%), urine (1,6%) et sonde urinaire (1,6%). Le pyocyanique se situe après le staphylocoque pour les prélèvements précoces et repasse en tête après un séjour supérieur à une semaine, où 89% des pyocyaniques sont identifiés. Il est en première position dans les pneumopathies sous ventilation assistée invasive. Il se classe troisième dans les hémocultures et les cultures de cathéters. Dans les infections urinaires il est devancé par Candida et la flore périnéale. Les 128 antibiogrammes regroupent 314 réponses sensibles. La sensibilité à plus de deux antibiotiques est de 68%, à deux antibiotiques 24% et à un antibiotique 8%. Seules quatre molécules restent actives: ciprofloxacine > péfloxacine > pipéracilline > ceftazidime. Une résistance absolue est retrouvée pour trois Pseudomonas (2,4%). Le pronostic sévère des infections nosocomiales à pyocyanique et les risques d'options thérapeutiques très limitées font toute leur gravité, d'où l'intérêt de respecter des règles strictes de prescription des antibiotiques et des mesures de prévention. PMID:21991140

Effet paradoxal du type d’excision sur la prise et le délai de cicatrisation des greffes expansées pour le traitement des brûlures aiguës: a propos de 1129 cas

PubMed Central

Guibert, M.; Chaouat, M.; Boccara, D.; Marco, O.; Lavocat, R.; Alameri, O.; Deslandes, E.; Montlahuc, C.; Mimoun, M.

2016-01-01

Summary La greffe de peau mince expansée est très employée dans le traitement des brûlures aiguës. Nous avons étudié l’influence de la préparation du sous-sol sur le taux de prise et le délai de cicatrisation des greffes expansées. Nous avons analysé rétrospectivement les 1 129 greffes expansées réalisées dans notre service entre 1995 et 2005 pour le traitement des brûlures aiguës. Leur taux de prise a été significativement meilleur après une préparation du sous-sol par avulsion (82%) par rapport à une préparation du sous-sol par excision tangentielle (75%). Ce taux était meilleur lorsque l’avulsion était pratiquée dans les 7 jours suivant la brûlure (83% vs 73%). Pour une prise en charge entre 7 et 21 jours, ce taux a semblé être meilleur après excision tangentielle, mais de façon non significative. La durée d’évolution jusqu’à cicatrisation était significativement raccourcie pour une préparation du sous-sol par excision tangentielle par rapport à une préparation du sous-sol par avulsion. Ces résultats montrent, paradoxalement, qu’une préparation du sous-sol par avulsion favorise la prise des greffes expansées mais rallonge leur délai de cicatrisation au contraire de l’excision tangentielle. PMID:28149235

The Adverse Effects of Le Châtelier's Principle on Teacher Understanding of Chemical Equilibrium

NASA Astrophysics Data System (ADS)

Cheung, Derek

2009-04-01

Although the scientific inadequacy of Le Châtelier's principle has long been documented in the literature, the principle is still treated as a central concept of chemical equilibrium by textbook writers and teachers in many countries. In the past, researchers' interest has focused on student misconceptions about chemical equilibrium and has neglected teacher misconceptions. This study aimed to determine how Le Châtelier's principle adversely affects teachers' ability to solve chemical equilibrium problems. This area of research is critically important because teachers cannot help their students understand what they themselves do not understand. In this study, a misconception test was developed and administered to a sample of 33 secondary chemistry teachers in Hong Kong. The test consisted of three open-ended chemical equilibrium questions. Analysis of teacher responses revealed that most of the 33 teachers failed the test as they relied on Le Châtelier's principle rather than the equilibrium law to tackle the three chemical equilibrium problems. Teachers' misconceptions about chemical equilibrium were categorized. Implications of these findings for chemistry teacher education and selection of curriculum content for school chemistry are discussed.

A multicolor panel of novel lentiviral "gene ontology" (LeGO) vectors for functional gene analysis.

PubMed

Weber, Kristoffer; Bartsch, Udo; Stocking, Carol; Fehse, Boris

2008-04-01

Functional gene analysis requires the possibility of overexpression, as well as downregulation of one, or ideally several, potentially interacting genes. Lentiviral vectors are well suited for this purpose as they ensure stable expression of complementary DNAs (cDNAs), as well as short-hairpin RNAs (shRNAs), and can efficiently transduce a wide spectrum of cell targets when packaged within the coat proteins of other viruses. Here we introduce a multicolor panel of novel lentiviral "gene ontology" (LeGO) vectors designed according to the "building blocks" principle. Using a wide spectrum of different fluorescent markers, including drug-selectable enhanced green fluorescent protein (eGFP)- and dTomato-blasticidin-S resistance fusion proteins, LeGO vectors allow simultaneous analysis of multiple genes and shRNAs of interest within single, easily identifiable cells. Furthermore, each functional module is flanked by unique cloning sites, ensuring flexibility and individual optimization. The efficacy of these vectors for analyzing multiple genes in a single cell was demonstrated in several different cell types, including hematopoietic, endothelial, and neural stem and progenitor cells, as well as hepatocytes. LeGO vectors thus represent a valuable tool for investigating gene networks using conditional ectopic expression and knock-down approaches simultaneously.

The NASA LeRC regenerative fuel cell system testbed program for goverment and commercial applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Maloney, T.M.; Prokopius, P.R.; Voecks, G.E.

1995-01-25

The Electrochemical Technology Branch of the NASA Lewis Research Center (LeRC) has initiated a program to develop a renewable energy system testbed to evaluate, characterize, and demonstrate fully integrated regenerative fuel cell (RFC) system for space, military, and commercial applications. A multi-agency management team, led by NASA LeRC, is implementing the program through a unique international coalition which encompasses both government and industry participants. This open-ended teaming strategy optimizes the development for space, military, and commercial RFC system technologies. Program activities to date include system design and analysis, and reactant storage sub-system design, with a major emphasis centered upon testbedmore » fabrication and installation and testing of two key RFC system components, namely, the fuel cells and electrolyzers. Construction of the LeRC 25 kW RFC system testbed at the NASA-Jet Propulsion Labortory (JPL) facility at Edwards Air Force Base (EAFB) is nearly complete and some sub-system components have already been installed. Furthermore, planning for the first commercial RFC system demonstration is underway. {copyright} {ital 1995} {ital American} {ital Institute} {ital of} {ital Physics}« less

Is Le Fort I Osteotomy Associated With Maxillary Sinusitis?

PubMed

Nocini, Pier Francesco; D'Agostino, Antonio; Trevisiol, Lorenzo; Favero, Vittorio; Pessina, Mattia; Procacci, Pasquale

2016-02-01

The purpose of the present study was to investigate the association between Le Fort I osteotomy and the anatomic, radiologic, and symptomatic modifications of the maxillary sinus. Subjects who had undergone Le Fort I osteotomy from January 2008 to December 2013 were enrolled in a retrospective cohort study. The eligibility criteria were the availability of a cone beam computed tomography (CBCT) scan taken before and 12 to 24 months after the procedure. The exclusion criteria were the unavailability of CBCT scans, the use of tobacco, and previous orthognathic procedures. The primary predictor variable was time (pre-vs postoperative). The primary outcome variables were the sinus volume, mucosal thickening, iatrogenic alterations in the sinus anatomy, and rhinosinusitis symptoms, evaluated using the Sino-Nasal Outcome 20-item Test (SNOT-20). Descriptive statistics were computed for each variable, and paired analyses were used to compare the pre- and postoperative values. The data from 64 subjects (mean age 27; 59.4% were female; median follow-up 32.4 months, range 13 to 66 months) were studied. Postoperatively, 1.6% of the sample (0% preoperatively) had moderate-to-severe and 15.6% (3.1% preoperatively) had mild-to-moderate sinusitis symptoms. The rest of the sample presented with mild to no symptoms. The increase in the SNOT scores after surgery was statistically significant (P = .016). Radiologic evidence of postoperative inflammatory processes affecting the paranasal sinuses was found in 27.3% of the sinuses (9.4% preoperatively). The postoperative Lund-Mackay scores were significantly greater (P = .0005). A 19% decrease was found in the mean postoperative sinus volume, with a 37% incidence of iatrogenic injury. The study results indicate that Le Fort I osteotomies can have an important impact on sinus health. The postoperative radiologic evidence of maxillary sinus inflammatory processes and the incidence of rhinosinusitis symptoms and iatrogenic damage in these

Infection par le VIH chez les patientes atteintes de cancer du sein en Guinée (Afrique de l'Ouest)

PubMed Central

Traore, Bangaly; Diane, Solomana; Sow, Mamadou Saliou; Keita, Mamady; Conde, Mamoudou; Traore, Fodé Amara; Kourouma, Tidiane

2015-01-01

L'objectif était de déterminer la prévalence de l'infection à VIH chez les patientes atteintes de cancer du sein et de comparer les caractéristiques anatomocliques et thérapeutiques de ces cancers du sein par rapports aux patientes non infectées par le VIH. Il s'agissait d'une étude rétrospective et analytique comparant les dossiers de patientes atteintes de cancers du sein histologiquement confirmés, infectées ou non par le VIH à l'unité de chirurgie oncologique de Donka, CHU de Conakry, de 2007 à 2012. Nous avons colligé 278 patientes présentant un cancer du sein dont 14 (5,0%) infectées par le VIH et 264 (95,0%) non infectées par le VIH. Les différences observées entre ces deux groupes de patientes étaient respectivement: âge médian (36,8 vs 49,0 ans), la ménopause (21,4% vs 53,4%), le nombre des patientes traitées (50,0% contre 77,1%) et la survenue de décès (78,6% vs 50,8%). Aucune différence n'a été notée dans la présentation clinique, histologique et le retard de consultation. Dans notre étude, la prévalence de l'infection à VIH chez les patients atteints de cancer du sein est élevée. L’âge jeune des patients, la faible accessibilité au traitement et la mortalité élevée doivent être confirmés par une étude sur un échantillon plus large. PMID:26523196

Etude des interdiffusions en phase solide dans le contact Er/GaAs

NASA Astrophysics Data System (ADS)

Députier, S.; Guivarc'h, A.; Caulet, J.; Minier, M.; Guérin, R.

1994-05-01

de mettre en évidence, en fonction de la température de recuit, plusieurs étapes successives d'interaction correspondant à des mélanges de phases, essentiellement des binaires. Elles dépendent fortement de l'orientation du substrat de GaAs, en particulier l'étape finale des interactions. Sur GaAs (001), seules deux étapes ont été observées : avant 600 ^{circ}C, il n'y a pas d'interaction visible de l'erbium avec le substrat ; celle-ci ne s'amorce qu'à 600 ^{circ}C pour n'évoluer ensuite que faiblement et conduire, à 800 ^{circ}C, à une composition nominale " Er{10}GaAs ", mélange des phases Er5Ga3 + Er + ErAs. Sur GaAs (111), plusieurs étapes d'interaction sont observées : l'erbium réagit avec le substrat dès 400 ^{circ}C (mélange des phases Er5Ga3 + Er), puis l'interaction se poursuit à 600 ^{circ}C (mélange Er5Ga3 + Er + ErAs) avant d'atteindre à 800 ^{circ}C la composition nominale " Er{1,5}GaAs ", constituée d'un mélange de grains des trois binaires ErAs + ErGa2 + Er3Ga5. Il faut noter que le recuit à 800 ^{circ}C n'est pas suffisant pour atteindre le mélange de phases Ga + ErAs qui, selon le diagramme ternaire, devrait être le stade ultime de l'interaction Er/GaAs. L'analyse des interdiffusions Er/GaAs montre que ErAs est le composé " clé " autour duquel pivote l'interaction Er/GaAs. Ce composé apparaît comme un candidat idéal pour la réalisation d'hétérostructures épitaxiées ErAs/GaAs.

Characterization and remediation of Soil Contaminated with Explosives: Development of Practical Technologies

DTIC Science & Technology

2001-07-06

Chemistry Agnes Renoux, Ph.D. Ecotoxicology Bernard Lachance, Ph. D. Ecotoxicology Ping Gong, Ph. D. Ecotoxicology Pierre-Yves Robidoux, Ph.D... Ecotoxicology Tamara Sheremata, Ph. D. Env. Engineering Diane Fournier, Ph.D. Microbiology Annamaria Halasz, M.Sc. Chemistry Louise Paquet, B.Sc...12 Chapter 4: Applied Ecotoxicology

Le point sur les amas de galaxies

NASA Astrophysics Data System (ADS)

Pierre, M.

galaxies jouent donc un rôle de premier plan dans toute étude cosmologique et par conséquent, sont indispensables à notre compréhension globale de l'univers. Dans l'introduction générale, nous détaillons cet aspect fondamental en montrant comment l'étude des amas peut contribuer à contraindre les scénarios cosmologiques. Une fois le contexte scientifique délimité, les chapitres suivants s'attachent à présenter les diverses propriétés des amas et leur évolution cosmique observée dans diverses longueurs d'onde principalement dans les domaines visible (galaxies), X (gaz) et radio (gaz et particules). Nous verrons que l'étude détaillée d'un amas implique celle de l'interaction entre ses différentes composantes et est un passage obligé pour remonter au paramètre ultime (ou premier) qu'est sa masse. Loin d'être un détour ennuyeux, ceci sera l'occasion d'aborder des phénomènes physiques extrêmement variés tel l'aspect multi-phases du milieu intra-amas, les sursauts de formation d'étoiles et l'évolution morphologique des galaxies capturées par les amas, ou bien encore, l'interaction entre le plasma intra-amas et les particules relativistes accélérées lors de la fusion entre deux amas. Bien sûr, pour chaque longueur d'onde, nous ne manquerons pas de décrire simplement les techniques d'observation et d'analyse mises en oeuvre ; celles-ci sont particulièrement intéressantes dans le cas de l'instrumentation spatiale. Nous terminerons en présentant des projets d'observatoires pour l'horizon 2010 et leur impact prévu sur l'étude des amas de galaxies.

Le risque de détresse morale dans la pratique contemporaine des soins de santé.

PubMed

Austin, Wendy

2016-05-01

Les professionnels de la santé sont des agents moraux dont la relation fiduciaire avec le public est animée par la responsabilité et la promesse de puiser dans leurs connaissances et leurs habiletés pour aider les personnes sous leurs soins. Lorsque leur capacité à tenir cette promesse est freinée ou compromise, ils risquent de souffrir de détresse morale. Le concept de détresse morale est défini et mis en contexte dans le milieu de la santé. Les contraintes et les facteurs qui en sont à l'origine sont présentés, de même que les moyens utilisés par les professionnels de la santé et les organisations de santé pour la soulager. Un changement transformateur s'impose pour vaincre la culture du silence et maintenir un système de santé où il est possible de vivre avec sa conscience. © 2016 The Canadian College of Health Leaders.

Le satellite Encelade source d'ions N+ dans la magnétosphère de Saturne

NASA Astrophysics Data System (ADS)

Bouhram, Mehdi; Berthelier, Jean-Jacques; Illiano, Jean-Marie; Smith, Howard T.; Sittler, Edward C.; Crary, Frank J.; Young, Dave T.

2005-12-01

xml:lang="fr">RésuméLe premier passage de la sonde Cassini dans l'environnement de Saturne, au dessus de l'anneau E, a mis en évidence l'existence d'un plasma composé d'un mélange d'ions issus des produits de l'eau (H+, O+, OH+, H2O+) avec une faible composante en ions N+ (3 %). A partir d'un modèle simple du transport des ions dans la magnétosphère, nous montrons que la source de ces ions N+ coïncide avec le satellite Encelade. Un tel résultat peut s'expliquer par la présence de composés volatiles tels que l'ammoniac NH3 sur ce satellite de glace, supposé encore actif géologiquement, ou par la présence d'ions N+ d'origine externe préalablement implantés sur sa surface. Pour citer cet article : M. Bouhram et al., C. R. Physique 6 (2005).

The Discovery of an 1862 Drawing of M 51, the Whirlpool Nebula

NASA Astrophysics Data System (ADS)

Holberg, Jay B.; Tobin, W.

2006-12-01

An early drawing of the spiral galaxy Messier 51 in Canes Venatici has recently come to light. The drawing was made on 25 April 1862 by Jean Chacornac (1823-1873), at the Paris Observatory, using Léon Foucault’s then newly completed 80-cm silvered-glass reflector. Chacornac’s observation of M 51 was among the first results from the new telescope announced to the Académie des Sciences by observatory director Urbain Verrier in 1862. Although the existence of the drawing was known from Le Verrier’s description, the original had never been located. The circumstances surrounding the origin and the discovery of this drawing will be discussed and a brief comparison will be made with other nineteenth century drawings and photographs of M 51.

Who invented the mule deer (Odocoileus hemionus)? On the authorship of the fraudulent 1812 journal of Charles Le Raye

USGS Publications Warehouse

Woodman, Neal

2015-01-01

The captivity journal of Charles Le Raye was first published in 1812 as a chapter in A topographical description of the state of Ohio, Indiana Territory, and Louisiana, a volume authored anonymously by a late officer in the U. S. Army. Le Raye was purported to be a French Canadian fur trader who, as a captive of the Sioux, had travelled across broad portions of the Missouri and Yellowstone river drainages a few years before the Lewis and Clark expedition (1804-1806), and his account of the land, its people, and its natural resources was relied upon as a primary source by generations of natural historians, geographers, and ethnographers. Based directly on descriptions of animals in the published journal, the naturalist Constantine S. Rafinesque named seven new species of North American mammals, including what are currently recognized as the mule deer (Odocoileus hemionus) and a Great Plains subspecies of white-tailed deer (O. virginianus macrourus). Unfortunately, Le Raye never existed, and historical, geographical, and ethnographical evidence indicates that the journal is fraudulent. Determining the author of this work is relevant to identifying the sources used to construct it, which may help us to understand the real animals upon which Rafinesque's species are based. Traditionally, authorship of the volume was attributed to Jervis Cutler, but his role in composing the fraudulent Le Raye journal has been called into question. In this paper, I present additional evidence supporting the hypothesis that Jervis Cutler bears primary responsibility for the Le Raye journal and that he had the background, opportunity, and potential motive to author it.

Etude par Imagerie à faible Niveau dans le proche Infrarouge d'une Emission de la haute Atmosphère

NASA Astrophysics Data System (ADS)

Pautet, Pierre-Dominique

2000-12-01

Le travail effectué a eu pour but la mise en place d'un protocole d'observation et de traitement des images, ainsi que les outils appropriés, visant à l'étude d'une émission de la haute atmosphère terrestre dans le proche infrarouge. Il existe actuellement des télescopes comme le VLT (Very Large Telescope), installé au Chili, qui permettent d'observer des astres et des galaxies distants de plusieurs millions de parsecs. A cause de l'expansion de l'Univers, des objets situés aussi loin s'éloignent très rapidement de nous. Le spectre de leur émission qui nous parvient alors est décalé vers le rouge ou l'infrarouge, du fait de l'effet Doppler. Il faut donc observer ces objets dans des longueurs d'onde appropriées. Malheureusement, l'atmosphère terrestre qui nous sépare d'eux est aussi le siège de nombreuses émissions qui peuvent venir perturber les mesures. De toutes ces émissions, la principale est due au radical OH dont les raies de rotation-vibration couvrent tout le spectre entre 0,7 et 2,5 microns. Cette émission a lieu au niveau d'une couche assez fine de la haute atmosphère appelée mésopause et située à environ 85 kilomètres d'altitude. Le travail effectué a eu pour but de mettre en évidence les principales caractéristiques de cette émission qui n'est pas uniforme et constante dans le temps. Un programme d'observations dans le proche infrarouge a été élaboré. Plusieurs algorithmes de traitement d'image ont été développés. Un programme d'inversion de perspective a été mis au point pour une utilisation en temps réel sur le terrain. Les caractéristiques des images peuvent être ensuite analysées. La première partie du mémoire comporte une description des différentes émissions lumineuses que l'on peut observer la nuit lorsque l'on regarde la voûte céleste. Ces émissions peuvent avoir deux origines: astronomique ou atmosphérique. Le problème de l'absorption atmosphérique et plus précisément les conditions

Assessment of pterygomaxillary separation in Le Fort I Osteotomy in class III patients.

PubMed

Ueki, Koichiro; Hashiba, Yukari; Marukawa, Kohei; Okabe, Katsuhiko; Alam, Shamiul; Nakagawa, Kiyomasa; Yamamoto, Etsuhide

2009-04-01

To examine the separation of the pterygomaxillary region at the posterior nasal spine level after Le Fort I osteotomy in Class III patients. The study group consisted of 37 Japanese patients with mandibular prognathism and asymmetry, with maxillary retrognathism or asymmetry. A total of 74 sides were examined. Le Fort I osteotomy was performed without a pterygoid osteotome, with an ultrasonic curette used to remove interference at the pterygomaxillary region. Postoperative computed tomography (CT) was analyzed for all patients. The separation of the pterygomaxillary region and the location of the descending palatine artery were assessed. Although acceptable separation between the maxilla and pterygoid plates was achieved in all patients, an exact separation of the pterygomaxillary junction at the posterior nasal spine level was found in only 18 of 74 sides (24%). In 29 of 74 sides (39.2%), the separation occurred anterior to the descending palatine artery. In 29 of 74 sides (39.2%), complete separation between the maxilla and lateral and/or medial pterygoid plate was not achieved, but lower level separation of the maxilla and pterygoid plate was always complete. The maxillary segments could be moved to the postoperative ideal position in all cases. Le Fort I osteotomy without an osteotome does not always induce an exact separation at the pterygomaxillary junction at the posterior nasal spine level, but the ultrasonic bone curette can remove the interference between maxillary segment and pterygoid plates more safely.

Traumatic Brain Injury in a Military Operational Setting (Le traumatisme cranien dans un cadre militaire operationnel)

DTIC Science & Technology

2015-01-01

la gestion du TCCL lié à un déploiement. Les objectifs de ce rapport étaient de : 1) Décrire la pratique clinique... de la projection de débris et à l’accélération/décélération ou rotation. L’impact sur la santé publique du TCCL lié à un déploiement sur tout...montré que le cours clinique du TCCL provoqué par une déflagration présente de forts parallèles avec ce qu’on constate dans la littérature sur le

The raft of the Saint-Jean River, Gaspé (Québec, Canada): A dynamic feature trapping most of the wood transported from the catchment

NASA Astrophysics Data System (ADS)

Boivin, Maxime; Buffin-Bélanger, Thomas; Piégay, Hervé

2015-02-01

The rivers of the Gaspé Peninsula, Québec (Canada), a coastal drainage system of the St. Lawrence River, receive and transport vast quantities of large wood. The rapid rate of channel shifting caused by high-energy flows and noncohesive banks allows wood recruitment that in turn greatly influences river dynamics. The delta of the Saint-Jean River has accumulated wood since 1960, leading to frequent avulsions over that time period. The wood raft there is now more than 3-km in length, which is unusual but natural. This jam configuration allows a unique opportunity to estimate a wood budget at the scale of a long river corridor and to better understand the dynamics of large wood (LW) in rivers. A wood budget includes the evaluation of wood volumes (i) produced by bank erosion (input), (ii) still in transit in the river corridor (deposited on sand bars or channel edges), and (iii) accumulated in the delta (output). The budget is based on an analysis of aerial photos dating back to 1963 as well as surveys carried out in 2010, all of which were used to locate and describe large wood accumulations along a 60-km river section. The main results of this paper show that the raft formation in the delta is dynamic and can be massive, but it is a natural process. Considering the estimated wood volume trapped in the delta from 1963 to 2013 (≈ 25,000 m3), two important points are revealed by the quantification of the wood recruitment volume from 1963 to 2004 (≈ 27,000 m3 ± 400 m3) and of the wood volume stored on the bars in 2010 (≈ 5950 m3). First, the recruitment of large wood from lateral migration for the 40-year period can account for the volume of large wood in the delta and in transit. Second, the excess wood volume produced by lateral migration and avulsion represents a minimum estimation of the large wood trapped on the floodplain owing to wood volume that has decomposed and large wood that exited the river system. Rafts are major trapping structures that provide

Interet du Lambeau Hypogastrique Dans le Traitement des Sequelles de Brulure de la Face Dorsale de la Main

PubMed Central

Tourabi, K.; Moussaoui, A.; Ribag, Y.; Ihrai, H.

2010-01-01

Summary Le lambeau hypogastrique est un lambeau cutané axial, vascularisé par le pédicule épigastrique inférieur superficiel. Il constitue un des moyens efficaces pour la couverture de la face postérieure de la main et du poignet. Quatre patients ont bénéficié de la couverture de la perte de substance après que l’excision du placard cicatriciel a fait appel au lambeau hypogastrique sevré au 21ème jour. Les résultats esthétiques et fonctionnels étaient plutôt satisfaisants. Ce lambeau constitue une technique de choix dans le traitement des séquelles de brûlures de la main avec exposition des éléments nobles; de dissection facile, donne peu de complications, et nécessite des retouches à distance pour obtenir un résultat optimal. PMID:21991214

Anti-Le-Chatelet behavior driven by strong natural light

NASA Astrophysics Data System (ADS)

Antonyuk, B. P.

2007-01-01

We show that strong incoherent broad band light causes positive feedback in response to a static electric field in random media: electric current flows in opposite to a voltage drop direction; static polarization is induced in opposition to an applied electric field. This type of the electron motion amplifies the external action revealing anti-Le-Chatelet behavior. The applied static electric field is amplified up to the domain of optical damage of a silica glass ≈10 7 V/cm.

Molecular and cellular characterization of the tomato pollen profilin, LePro1

USDA-ARS?s Scientific Manuscript database

Profilin is an actin-binding protein involved in the dynamic turnover and restructuring of the actin cytoskeleton in all eukaryotic cells. We previously cloned a profilin gene, designated as LePro1 from tomato pollen. To investigate its biological role, in the present study, We investigated the tem...

75 FR 9028 - Quarterly Publication of Individuals, Who Have Chosen To Expatriate, as Required by Section 6039G

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-26

... ANWAR MELISSA M. S. ARMSTRONG ERIK BENTUNG ARTZ CHARLES EDWARD ASHER HANNIBAL DAVID AU ALICE MIU HING AU... BAUMBERGER YVES BELL CHARLES HENRY BERKES ROBERT A BERLIN LOUISE BHATTAL JASJIT SINGH BIEHLER SANDRA ANN... CHRISTIAN FREDERIK ALEXANDER BUCKLEY ARLENE CAMPBELL VIRGINIA ELLEN CARR RODERICK JAMES CHAN CHARLES TSUN...

Strategic Studies Quarterly. Volume 7, Number 2, Summer 2013

DTIC Science & Technology

2013-01-01

Handbook of Asian Regionalism Edited by: Mark Beeson and Richard Stubbs Reviewed by: Yves Laberge Maritime Challenges and Priorities in Asia...and Steven E. Miller (Cambridge, MA: MIT Press, 1993), 200-2. Van Evera in particular has opined that Europe has become "primed for peace" because

NREL Researchers Receive Award for Excellence in Technology Transfer

Science.gov Websites

. Department of Energy's National Renewable Energy Laboratory were honored May 10 with a Year 2000 Federal as applied in geothermal power plants. Award recipients are Desikan Bharathan, who developed the condenser technology, and the geothermal research team including Vahab Hassani, Yves Parent, Federica

Le lupus systémique juvénile familial: à propos de deux familles

PubMed Central

Krich, Sanaa; Inani, Kawtar; Meziane, Mariame; Souilmi, Fatima Zohta; Atmani, Samir; Hida, Mustapha; Harmouch, Taoufik; Amarti, Afaf; Mernissi, Fatima Zohra

2015-01-01

Le lupus érythémateux systémique (LES) juvénile est une connectivite rare, d’évolution plus sévère que chez l'adulte. Les cas familiaux sont exceptionnels. Il s'agissait de deux familles (5 patients atteints), chez qui on a objectivé un LES juvénile chez deux sæurs âgées de 14 ans et 6 ans respectivement chez la première famille, deux frères, âgés de 20 ans et 6 ans respectivement plus une sæur âgée de 10 ans chez la deuxième famille. Dans tout les cas le diagnostic de lupus systémique a été posé selon les nouveaux critères du groupe du SLICC (Systemic Lupus International Collaborating Clinics). Tous les patients ont été mis sous photoprotection, dermocorticoïdes et antipaludéens de synthèse sauf dans deux cas où la corticothérapie a été administrée. L’évolution a été favorable après le traitement dans la majorité des cas. Nous rapportons ces cas afin de discuter les particularités épidémiologiques, physiopathologiques, cliniques, paracliniques et thérapeutiques. PMID:26301023

Le transfert de connaissances entre les mathematiques et les sciences. Une etude exploratoire aupres d'eleves de 4e secondaire

NASA Astrophysics Data System (ADS)

Samson, Ghislain

2003-06-01

Au moment ou dans plusieurs pays on travaille a refondre les programmes d'etudes, tant au primaire qu'au secondaire, l'interet pour le transfert renait. Un des concepts fondamentaux en apprentissage consiste en l'habilete a reutiliser de facon consciente et efficace un acquis d'une situation a une autre situation. Cette recherche emane de preoccupations professionnelles au moment ou le chercheur etait enseignant au secondaire. Au cours de ces annees, il lui a ete possible de constater que plusieurs eleves percevaient difficilement les liens presents entre les disciplines mathematiques et scientifiques. Des travaux en psychologie cognitive et plus particulierement selon une perspective du traitement de l'information ont servi de cadre de reference pour evaluer et analyser les capacites de transfert aupres d'eleves de 4e secondaire. Ce cadre de reference permet de formuler le principal objectif qui est de mieux comprendre le processus de transfert chez des eleves en situation de resolution de problemes scientifiques. Cette these s'interesse donc au transfert en tant que phenomene important du processus d'apprentissage au sens de l'integration. La methode de recherche choisie, de nature qualitative, est principalement axee sur l'evaluation de la capacite a transferer des connaissances lors d'une epreuve et d'un entretien. Pour evaluer ce potentiel de transfert, nous avons elabore deux outils: une epreuve en mathematiques et en sciences et un guide d'entretien. Pour la passation de l'epreuve, le chercheur a pu compter sur la collaboration de 130 sujets provenant de deux ecoles. L'entretien complete la prise de donnees avec 13 sujets ayant accepte de poursuivre l'etude. Les donnees recueillies par ces instruments font ensuite l'objet d'une analyse de contenu. En premier lieu, les verbatims de l'epreuve et de l'entretien ont ete transcrits, puis codifies. La correction des reponses fournies pour les problemes resolus s'est faite a partir d'une grille d

Aspects épidémiologiques, diagnostiques et thérapeutiques des ostéosarcomes de l'enfant au CHU Aristide le Dantec de Dakar: à propos de 16 cas

PubMed Central

Ndour, Oumar; Alumeti, Desire Munyali; Fall, Mbaye; Fall, Aimée Faye; Diouf, Cheikh; Ndoye, Ndeye Aby; Ngom, Gabriel; Ndoye, Mamadou

2013-01-01

Le but de cette étude était de décrire les aspects épidémiologiques, diagnostiques et thérapeutiques des ostéosarcomes de l'enfant. Il s'agissait d'une étude rétrospective sur dix ans qui a colligé 16 dossiers d'ostéosarcome pris en charge au service de Chirurgie Pédiatrique de l'hôpital Aristide Le Dantec de Dakar. Les paramètres étudiés étaient le niveau d'instruction et le niveau socioprofessionnel des parents, l'origine géographique, l’âge, le sexe, les antécédents particuliers, le délai de consultation, les motifs de consultation, les signes physiques, les signes radiologiques, la biologie, les modalités thérapeutiques et l’évolution. Tous les patients avaient bénéficié d'un examen anatomopathologique qui a confirmé le diagnostic d'ostéosarcome. Pour la majeure partie de nos patients (58% des cas) les parents avaient un niveau d'instruction bas. L’âge moyen était de 11ans. Une prédominance masculine était retrouvée avec un sex-ratio de 3,25:1. Le délai de consultation moyen était de 16 mois. Le principal motif de consultation était la tuméfaction (10 cas). Huit patients avaient bénéficié d'un traitement traditionnel. La taille de la tumeur était supérieure à 10cm dans 14 cas. La localisation la plus fréquente était le genou (14 cas). La radiographie standard retrouvait dans 15 cas des images d'ostéolyse. Le bilan d'extension n'avait pas retrouvé de métastases. Les options thérapeutiques étaient dominées par l'amputation seule (43,75% des cas). La survie à 2 ans était de 17%. L'ostéosarcome atteint le plus souvent le garçon après l’âge de 10 ans. Sa prise en charge au Sénégal se heurte à d’énormes difficultés liées au retard diagnostique. La solution repose essentiellement sur une collaboration pluridisciplinaire. PMID:23720705

Nowcasting of meteorological risks during the winter season using the "Integrated Meteorological Observation Network in Castilla y León, (Spain)"

NASA Astrophysics Data System (ADS)

Guerrero-Higueras, Ángel Manuel; López, Laura; Merino, Andrés; Sánchez, José Luis; Matía, Pedro; Lorente, José Manuel; Hermida, Lucía; Nafría, David; Ortiz de Galisteo, José Pablo; Marcos, José Luis; García-Ortega, Eduardo

2013-04-01

The location of Castilla y León within the Iberian Peninsula and its territorial extension make its meteorological risks diverse. The integration of various observation networks, both public and private, in the Observation Network of Castilla y León, allows us to follow the risks in real-time. One of the most frequent risks in the winter season is snow precipitation. In the present paper, we compared WRF numerical model predictions of snowfall for Castilla y León with data from the meteorological observation network and observations from the MSG satellite. Furthermore, frosts were more frequent in the area, to the point that there are parts of the study area with frost during the entire year. Thus, the data from the network allows us to determine the area where frost was registered. Finally, the situations with fog, especially with advective and radiative characteristics, are frequent in the center and south of the plateau, especially in the winter season. Additionally, the Observation Network allows us to know the areas with fog in real-time. The Observation Network is managed using a new platform, developed by Group for Atmospheric Physics, known as MeteoNet, which allows for the prompt extraction of a concrete parameter in a specific location, or, the spatial representation of a parameter determined for the entire study area. Furthermore, the management system developed for the data allows for the total representation of data from the WRF prediction model, with satellite images, observation network, radar data, etc., which is converted into a very useful tool for following risks and validating algorithms in Castilla y León. Acknowledgements The authors would like to thank the Regional Government of Castilla y León for its financial support through the project LE220A11-2.

Connaissances des médecins généralistes de Mohammedia (Maroc) concernant le dépistage du cancer du sein

PubMed Central

Zine, Karima; Nani, Samira; Lahmadi, Imad Ait; Maaroufi, Abderrahmane

2016-01-01

Introduction Le cancer du sein représente un problème de santé publique majeur au Maroc. C'est le premier cancer chez la femme. L'objectif de ce travail était d'évaluer les connaissances des médecins généralistes (MG) en matière de dépistage du cancer du sein dans la préfecture de Mohammedia Maroc. Méthodes Nous avons mené une étude transversale, descriptive, exhaustive incluant les 97 MG exerçant dans les établissements de soins de santé de base du secteur public et privé de la province de Mohammedia. Résultats Le taux de participation était de 87%. L'âge moyen des MG était de 49,6 ± 8,1. Quatre-vingt pour cent (n=55) des MG ont donné une incidence incorrecte, 77,6% (n=85) ont reconnu l'existence d'un plan national de prévention et de contrôle du cancer (PNPCC) au Maroc, et 67,1 des MG ont rapporté l'existence d'un registre du cancer au Maroc. Le secteur d'activité était associé significativement avec les connaissances des MG sur le PNPCC et sur l'existence d'un guide de détection précoce du cancer du sein avec respectivement (p=0,003 et p=0,001). Une association significative entre l'ancienneté et l'existence d'un guide de détection précoce du cancer du sein et d'un registre du cancer du sein a été retrouvée avec (respectivement p=0,005 et p=0.002). Conclusion À la lumière de ces résultats il faudra renforcer les connaissances et les pratiques des MG par la promotion de la formation initiale et continue sur le dépistage. PMID:27800098

Technique distribuee de gestion de la charge sur le reseau electrique et ring-tree: Un nouveau systeme de communication P2P

NASA Astrophysics Data System (ADS)

Ayoub, Simon

Le reseau de distribution et de transport de l'electricite se modernise dans plusieurs pays dont le Canada. La nouvelle generation de ce reseau que l'on appelle smart grid, permet entre autre l'automatisation de la production, de la distribution et de la gestion de la charge chez les clients. D'un autre cote, des appareils domestiques intelligents munis d'une interface de communication pour des applications du smart grid commencent a apparaitre sur le marche. Ces appareils intelligents pourraient creer une communaute virtuelle pour optimiser leurs consommations d'une facon distribuee. La gestion distribuee de ces charges intelligentes necessite la communication entre un grand nombre d'equipements electriques. Ceci represente un defi important a relever surtout si on ne veut pas augmenter le cout de l'infrastructure et de la maintenance. Lors de cette these deux systemes distincts ont ete concus : un systeme de communication peer-to-peer, appele Ring-Tree, permettant la communication entre un nombre important de noeuds (jusqu'a de l'ordre de grandeur du million) tel que des appareils electriques communicants et une technique distribuee de gestion de la charge sur le reseau electrique. Le systeme de communication Ring-Tree inclut une nouvelle topologie reseau qui n'a jamais ete definie ou exploitee auparavant. Il inclut egalement des algorithmes pour la creation, l'exploitation et la maintenance de ce reseau. Il est suffisamment simple pour etre mis en oeuvre sur des controleurs associes aux dispositifs tels que des chauffe-eaux, chauffage a accumulation, bornes de recharges electriques, etc. Il n'utilise pas un serveur centralise (ou tres peu, seulement lorsqu'un noeud veut rejoindre le reseau). Il offre une solution distribuee qui peut etre mise en oeuvre sans deploiement d'une infrastructure autre que les controleurs sur les dispositifs vises. Finalement, un temps de reponse de quelques secondes pour atteindre 1'ensemble du reseau peut etre obtenu, ce qui est

Systeme microfluidique d'analyse sanguine en temps reel pour l'imagerie moleculaire chez le petit animal

NASA Astrophysics Data System (ADS)

Convert, Laurence

De nouveaux radiotraceurs sont continuellement développés pour améliorer l'efficacité diagnostique en imagerie moléculaire, principalement en tomographie d'émission par positrons (TEP) et en tomographie d'émission monophotonique (TEM) dans les domaines de l'oncologie, de la cardiologie et de la neurologie. Avant de pouvoir être utilisés chez les humains, ces radiotraceurs doivent être caractérisés chez les petits animaux, principalement les rats et les souris. Pour cela, de nombreux échantillons sanguins doivent être prélevés et analysés (mesure de radioactivité, séparation de plasma, séparation d'espèces chimiques), ce qui représente un défi majeur chez les rongeurs à cause de leur très faible volume sanguin (˜1,4 ml pour une souris). Des solutions fournissant une analyse partielle sont présentées dans la littérature, mais aucune ne permet d'effectuer toutes les opérations dans un même système. Les présents travaux de recherche s'insèrent dans le contexte global d'un projet visant à développer un système microfluidique d'analyse sanguine complète en temps réel pour la caractérisation des nouveaux radiotraceurs TEP et TEM. Un cahier des charges a tout d'abord été établi et a permis de fixer des critères quantitatifs et qualitatifs à respecter pour chacune des fonctions de la puce. La fonction de détection microfluidique a ensuite été développée. Un état de l'art des travaux ayant déjà combiné la microfluidique et la détection de radioactivité a permis de souligner qu'aucune solution existante ne répondait aux critères du projet. Parmi les différentes technologies disponibles, des microcanaux en résine KMPR fabriqués sur des détecteurs semiconducteurs de type p-i-n ont été identifiés comme une solution technologique pour le projet. Des détecteurs p-i-n ont ensuite été fabriqués en utilisant un procédé standard. Les performances encourageantes obtenues ont mené à initier un projet de ma

8. VIEW FORWARD IN CREW'S QUARTERS (FOC'S'LE) SHOWING DOUBLE TIER ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

8. VIEW FORWARD IN CREW'S QUARTERS (FOC'S'LE) SHOWING DOUBLE TIER OF BUNKS IN THE EVELINA M. GOULART. KINGPOST IS AT CENTER OF PHOTOGRAPH WITH FORE PEAK IN BACKGROUND. A FOLDING MESS TABLE IS AT LOWER LEFT OF PHOTOGRAPH. NOTE BENCH SEAT BELOW LOWEST TIER OF BUNKS. - Auxiliary Fishing Schooner "Evelina M. Goulart", Essex Shipbuilding Museum, 66 Main Street, Essex, Essex County, MA

The Potassium-Argon Laser Experiment (KArLE): In Situ Geochronology for Planetary Robotic Missions

NASA Technical Reports Server (NTRS)

Cohen, Barbara

2016-01-01

The Potassium (K) - Argon (Ar) Laser Experiment (KArLE) will make in situ noble-gas geochronology measurements aboard planetary robotic landers and roverss. Laser-Induced Breakdown Spectroscopy (LIBS) is used to measure the K abun-dance in a sample and to release its noble gases; the evolved Ar is measured by mass spectrometry (MS); and rela-tive K content is related to absolute Ar abundance by sample mass, determined by optical measurement of the ablated volume. KArLE measures a whole-rock K-Ar age to 10% or better for rocks 2 Ga or older, sufficient to resolve the absolute age of many planetary samples. The LIBS-MS approach is attractive because the analytical components have been flight proven, do not require further technical development, and provide complementary measurements as well as in situ geochronology.

Structures, thermal expansion properties and phase transitions of Er{sub x}Fe{sub 2-x}(MoO{sub 4}){sub 3} (0.0 {le} x {le} 2.0).

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cheng, Y. Z.; Wu, M. M.; Peng, J.

2007-05-03

Structures, thermal expansion properties and phase transitions of Er{sub x}Fe{sub 2-x}(MoO{sub 4}){sub 3} (0.0 {le} x {le} 2.0) have been investigated by X-ray diffraction and differential thermal analysis. The partial substitution of Er{sup 3+} for Fe{sup 3+} induces pronounced decreases in the phase transition temperature from monoclinic to orthorhombic structure. Rietveld analysis of the XRD data shows that both the monoclinic and orthorhombic Fe{sub 2}(MoO{sub 4}){sub 3}, as well as the orthorhombic Er{sub x}Fe{sub 2-x}(MoO{sub 4}){sub 3} (x {le} 0.8) have positive thermal expansion coefficients. However, the linear thermal expansion coefficients of Er{sub x}Fe{sub 2-x}(MoO{sub 4}){sub 3} (x = 0.6-2.0)more » decrease with increasing content of Er{sup 3+} and for x {ge} 1.0, compounds Er{sub x}Fe{sub 2-x}(MoO{sub 4}){sub 3} show negative thermal expansion properties. Attempts for making zero thermal expansion coefficient materials result in that very low negative thermal expansion coefficient of -0.60 x 10{sup -6} C in Er{sub 1.0}Fe{sub 1.0}(MoO{sub 4}){sub 3} is observed in the temperature range of 180-400 C, and zero thermal expansion is observed in Er{sub 0.8}Fe{sub 1.2}(MoO{sub 4}){sub 3} in the temperature range of 350-450 C. In addition, anisotropic thermal expansions are found for all the orthorhombic Er{sub x}Fe{sub 2-x}(MoO{sub 4}){sub 3} compounds, with negative thermal expansion coefficients along the a axes.« less

Controle optique de qubits lies a des centres isoelectroniques d'azote dans le GaAs

NASA Astrophysics Data System (ADS)

Ethier-Majcher, Gabriel

Le traitement de l'information quantique est un domaine de recherche actuellement en pleine effervescence car il laisse entrevoir une revolution dans notre facon de traiter et d'echanger de l'information. D'une part, l'ordinateur quantique promet de resoudre des problemes comme la factorisation d'un polynome de facon beaucoup plus efficace qu'un ordinateur classique. D'autre part, les communications quantiques promettent l'echange d'information de facon fondamentalement inviolable. Afin de tirer pleinement profit de ces nouvelles technologies, il sera avantageux de construire des reseaux quantiques. Dans un tel reseau, des processeurs quantiques, les noeuds, seront connectes par des photons voyageant dans des fibres optiques. Les reseaux quantiques permettront de deployer les communications quantiques a grande echelle et de creer des super-ordinateurs quantiques. La realisation de reseaux quantiques necessitera des interfaces optiques pouvant echanger l'information de facon coherente entre un qubit (bit d'information quantique) et un photon. L'implementation de telles interfaces dans un systeme physique s'avere un important defi scientifique et technologique. Or, les systemes actuellement envisages a cette fin souffrent d'un faible couplage avec la lumiere ou encore de grandes inhomogeneites, constituant des obstacles a la realisation de reseaux a grande echelle. Dans cette these, le potentiel des centres isoelectroniques pour realiser des interfaces optiques est evalue. Deux types de qubits lies a des paires d'azote dans le GaAs sont consideres : les qubits excitoniques et les qubits de spin electronique, controlables par l'intermediaire d'excitons charges. Le controle optique complet des qubits excitoniques est demontre, ce qui constitue la premiere realisation du genre dans les centres isoelectroniques. L'observation d'excitons charges dans ce systeme, liant a la fois des trous lourds et des trous legers, laisse entrevoir de nouvelles possibilites afin de

Mécanismes et traitement de l’anémie aiguë chez le brûlé grave

PubMed Central

Siah, S.; El Khatib, K.; Messaoudi, N.

2016-01-01

Summary Les brûlés graves présentent souvent, au cours de la phase aiguë, des anémies plus au moins profondes pouvant nécessiter des transfusions. L’anémie du brûlé a deux origines principales: le saignement péri-opératoire (des stratégies doivent être mises en place pour le réduire) et l’anémie de réanimation (que l’on peut en partie réduire en évitant les bilans inutiles) chez un patient ayant des troubles de l’hématopoïèse. Le traitement, chez ces patients à l’hématopoïèse altérée, repose sur la transfusion. Celle-ci n’est pas dénuée d’effets secondaires et une stratégie transfusionnelle restrictive doit être appliquée. PMID:28149231

Theater in professor Charcot's galaxy.

PubMed

Poirier, Jacques; Philippon, Jacques

2013-01-01

Jean-Martin Charcot, famous professor of the Chair of Clinic for Diseases of the Nervous System at Salpêtrière Hospital in Paris, was himself an artist, surrounded by artists, and adored the theater. His close colleague Charles Brown-Séquard was ridiculed by Georges Feydeau in a brief freakish monologue recited by Coquelin Cadet, from the Comédie-Française, concerning his claims to rejuvenate himself and others with animal testicle extracts. His friend and patient Alphonse Daudet had written many novels, short stories, and plays. Léon Daudet, Alphonse Daudet's son (and friend of Jean-Baptiste Charcot, the son of the professor), after having abandoned his medical studies, became a writer whose novel Les morticoles was a cruel satire of the medical profession. Among Charcot's pupils, Alfred Binet, Gilbert Ballet, Édouard Brissaud, and Joseph Babinski were particularly involved in the theater. Gilbert Ballet wrote the foreword to La folie au théâtre (Madness in Theatre) by André de Latour. Édouard Brissaud wrote a satiric play Le chèque (The Check), and Joseph Babinski, under the pseudonym of Olaf, was the coauthor with Palau of the drama Les détraquées (The Deranged Women). However, when all is said and done, perhaps the greatest actor in his entourage was Charcot himself. Copyright © 2013 S. Karger AG, Basel.

On violations of Le Chatelier's principle for a temperature change in small systems observed for short times

NASA Astrophysics Data System (ADS)

Dasmeh, Pouria; Searles, Debra J.; Ajloo, Davood; Evans, Denis J.; Williams, Stephen R.

2009-12-01

Le Chatelier's principle states that when a system is disturbed, it will shift its equilibrium to counteract the disturbance. However for a chemical reaction in a small, confined system, the probability of observing it proceed in the opposite direction to that predicted by Le Chatelier's principle, can be significant. This work gives a molecular level proof of Le Chatelier's principle for the case of a temperature change. Moreover, a new, exact mathematical expression is derived that is valid for arbitrary system sizes and gives the relative probability that a single experiment will proceed in the endothermic or exothermic direction, in terms of a microscopic phase function. We show that the average of the time integral of this function is the maximum possible value of the purely irreversible entropy production for the thermal relaxation process. Our result is tested against computer simulations of the unfolding of a polypeptide. We prove that any equilibrium reaction mixture on average responds to a temperature increase by shifting its point of equilibrium in the endothermic direction.

Apport de la tomodensitométrie dans le diagnostic de la tuberculose vertébrale à propos de 496 cas à Abidjan

PubMed Central

Gbané-Koné, Mariam; Ouattara, Baly; Diomandé, Mohamed; Sessou, Viva; Kaboré, Fulgence; Djoko, Kouadio Flore; Traoré, Moriba; Eti, Edmond; Kouakou, N'zué Marcel

2015-01-01

Introduction Le mal de Pott est la forme la plus fréquente des tuberculoses ostéo articulaires, le diagnostic de certitude reste difficile. L'imagerie tient une place indéniable dans le diagnostic. L'objectif de cette étude était de déterminer la prévalence de la tuberculose vertébrale et l'apport de la TDM dans le diagnostic. Méthodes Nous avons mené une étude rétrospective sur dossiers de tuberculose vertébrale dans le service de Rhumatologie du CHU de Cocody de Janvier 2006 à Décembre 2013. N'ont pas été inclus dans l’étude, tous les dossiers ne comportant pas d'imagerie. Resultats La prévalence hospitalière de la tuberculose vertébrale était de 10,95%, elle représentait 90,2% de la tuberculose ostéoarticulaire. Elle concernait les 2 sexes, l’âge moyen était de 43,27 ans (4-88ans). L'atteinte dorsolombaire était la localisation la plus fréquente (95,13%). L'atteinte du rachis cervical était rare. La spondylodiscite était fréquente (92,14%). La spondylite (6%) et l'atteinte de l'arc postérieur (0,86%) étaient rares. La spondylodiscite était unique le plus souvent (70,05%), les formes multiétagées ont été notées dans 28,65% des cas, les atteintes mutifocales ont été notées dans14, 63% des cas. Les localisations inhabituelles étaient: atteinte sous occipitale (n=3), atteinte concomitante des 3 segments rachidiens (n=3), atteinte du sacrum (n=1), abcès isolés du psoas (n=4). La prévalence des abcès était de 85,91%, celle des épidurites était de 80,17%. La ponction scannoguidée des abcès a été réalisée dans 20 cas, la recherche de BAAR était positive dans 15 cas. Il existait une tuberculose viscérale évolutive dans 20% des cas. Conclusion La TDM est indéniable dans le diagnostic positif et lésionnel de la tuberculose vertébrale. Le retard au diagnostic explique l’étendue des lésions. PMID:26113932

High School Geography Project. Legacy for the Seventies. An Analysis of the High School Geography Project in Relation to New Developments in Geographic Education Worldwide.

ERIC Educational Resources Information Center

Gunn, Angus M., Ed.

Nine articles by geographers and educators analyze the High School Geography Project (HSGP). A project overview by Angus Gunn presents essential ideas and content of six units and several preliminary reactions. The question of "HSGP exportability" to France and Germany is examined in articles by Maurice Saint-Yves and Robert Geipel…

Life History and Biology of Ips latidens (LeConte) (Coleoptera: Scolytidae)\\t

Treesearch

D.R. Miller; J.H. Borden

1985-01-01

The life history and biology of Ips latidens (LeConte) were investigated using bark-sandwich and whole-log rearing methods. In contrast with other Ips spp., some females initiated galleries under conditions of female-biased sex ratios, and sometimes 2 or more males were present in a gallery. In general, however, I....

Reflections on "Petit Battement sur le Cou de Pied": Is It Still Relevant?

ERIC Educational Resources Information Center

Paskevska, Anna

2007-01-01

This article presents multiple perspectives of "petit battement sur le cou de pied". These perspectives include historical, biomechanical, and pedagogic points of view. The article offers useful information for ballet specialists and applied research studies aimed at ballet pedagogy. (Contains 2 tables and 5 figures.)