Sample records for jens jkel ronny

  1. Evolution of the carboxylate Jen transporters in fungi.

    PubMed

    Lodi, Tiziana; Diffels, Julie; Goffeau, André; Baret, Philippe V

    2007-08-01

    Synteny analysis is combined with sequence similarity and motif identification to trace the evolution of the putative monocarboxylate (lactate/pyruvate) transporters Jen1p and the dicarboxylate (succinate/fumarate/malate) transporters Jen2p in Hemiascomycetes yeasts and Euascomycetes fungi. It is concluded that a precursor form of Jen1p, named here preJen1p, arose by the duplication of an ancestral Jen2p, during the speciation of Yarrowia lipolytica, which was transferred into a new syntenic context. The Jen1p transporters differentiated from preJen1p in Kluyveromyces lactis, before the Whole Genome Duplication (WGD), and are conserved as a single copy in the Saccharomyces species. In contrast, the ancestral Jen2p was definitively lost just prior to the WGD and is absent in Saccharomyces.

  2. Report on Sabbatical activities - Dr. Ronnie Shepherd - 05/25/2014 to 08/21/2014

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Shepherd, Ronnie

    2014-10-09

    The sabbatical performed by Dr. Ronnie Shepherd from 05/25/2014 to 08/21/2014 had two central goals: 1) write three proposals for future collaborative experiments at Ecole Polytechnique (and possibly LLNL) 2) if laser time was granted (based on the proposal), perform a preliminary experiment in preparation for the campaign of laser time based on proposal submission.

  3. 'Diamond Jenness': Before the Grind

    NASA Technical Reports Server (NTRS)

    2004-01-01

    This microscopic imager mosaic of the rock called 'Diamond Jenness' was snapped on sol 177 before NASA's Mars Exploration Rover Opportunity ground into the surface with its rock abrasion tool, or 'Rat.'

    Opportunity has bored nearly a dozen holes into the inner walls of 'Endurance Crater.' On sols 177 and 178 (July 23 and July 24, 2004), the rover worked double-duty on Diamond Jenness. Surface debris and the bumpy shape of the rock resulted in a shallow and irregular hole, only about 2 millimeters (0.08 inch) deep. The final depth was not enough to remove all the bumps and leave a neat hole with a smooth floor. This extremely shallow depression was then examined by the rover's alpha particle X-ray spectrometer. On Sol 178, Opportunity's 'robotic rodent' dined on Diamond Jenness once again, grinding almost an additional 5 millimeters (about 0.2 inch). The rover then applied its Moessbauer spectrometer to the deepened hole. This double dose of Diamond Jenness enabled the science team to examine the rock at varying layers. Results from those grindings are currently being analyzed.

    The image mosaic is about 6 centimeters (2.4 inches) across.

  4. 'Diamond Jenness': A Tough Grind

    NASA Technical Reports Server (NTRS)

    2004-01-01

    This microscopic imager mosaic of the target area called 'Diamond Jenness' was taken after NASA's Mars Exploration Rover Opportunity ground into the surface with its rock abrasion tool for a second time.

    Opportunity has bored nearly a dozen holes into the inner walls of 'Endurance Crater.' On sols 177 and 178 (July 23 and July 24, 2004), the rover worked double-duty on Diamond Jenness. Surface debris and the bumpy shape of the rock resulted in a shallow and irregular hole, only about 2 millimeters (0.08 inch) deep. The final depth was not enough to remove all the bumps and leave a neat hole with a smooth floor. This extremely shallow depression was then examined by the rover's alpha particle X-ray spectrometer.

    On Sol 178, Opportunity's 'robotic rodent' dined on Diamond Jenness once again, grinding almost an additional 5 millimeters (about 0.2 inch). The rover then applied its Moessbauer spectrometer to the deepened hole. This double dose of Diamond Jenness enabled the science team to examine the rock at varying layers. Results from those grindings are currently being analyzed.

    The image mosaic is about 6 centimeters (2.4 inches) across.

  5. Safe at School: An Interview with Kevin Jennings

    ERIC Educational Resources Information Center

    Richardson, Joan

    2010-01-01

    This article presents an interview with Assistant Deputy Secretary of Education Kevin Jennings on his ideas about school safety. In this interview, Jennings describes his plans for making schools safer for students and for developing a way to measure school climate that can drive such changes. Bullied in school, Jennings now devotes his life to…

  6. 'Diamond Jenness': Before the Grind

    NASA Image and Video Library

    2004-08-03

    This microscopic imager mosaic of the rock called "Diamond Jenness" was snapped on sol 177 before NASA's Mars Exploration Rover Opportunity ground into the surface with its rock abrasion tool, or "Rat." Opportunity has bored nearly a dozen holes into the inner walls of "Endurance Crater." On sols 177 and 178 (July 23 and July 24, 2004), the rover worked double-duty on Diamond Jenness. Surface debris and the bumpy shape of the rock resulted in a shallow and irregular hole, only about 2 millimeters (0.08 inch) deep. The final depth was not enough to remove all the bumps and leave a neat hole with a smooth floor. This extremely shallow depression was then examined by the rover's alpha particle X-ray spectrometer. On Sol 178, Opportunity's "robotic rodent" dined on Diamond Jenness once again, grinding almost an additional 5 millimeters (about 0.2 inch). The rover then applied its Moessbauer spectrometer to the deepened hole. This double dose of Diamond Jenness enabled the science team to examine the rock at varying layers. Results from those grindings are currently being analyzed. The image mosaic is about 6 centimeters (2.4 inches) across. http://photojournal.jpl.nasa.gov/catalog/PIA06748

  7. 'Diamond Jenness': After the Grind

    NASA Technical Reports Server (NTRS)

    2004-01-01

    This microscopic imager mosaic taken by NASA's Mars Exploration Rover Opportunity shows the rock dubbed 'Diamond Jenness.' It was taken on sol 177 (July 23, 2004) after the rover first ground into the rock with its rock abrasion tool, or 'Rat.' The rover later ground into the rock a second time. A sliced spherule, or 'blueberry,' is visible in the upper left corner of the hole.

    Opportunity has bored nearly a dozen holes into the inner walls of 'Endurance Crater.' On sols 177 and 178 (July 23 and July 24, 2004), the rover worked double-duty on Diamond Jenness. Surface debris and the bumpy shape of the rock resulted in a shallow and irregular hole, only about 2 millimeters (0.08 inch) deep. The final depth was not enough to remove all the bumps and leave a neat hole with a smooth floor. This extremely shallow depression was then examined by the rover's alpha particle X-ray spectrometer.

    On Sol 178, Opportunity's 'robotic rodent' dined on Diamond Jenness once again, grinding almost an additional 5 millimeters (about 0.2 inch). The rover then applied its Moessbauer spectrometer to the deepened hole. This double dose of Diamond Jenness enabled the science team to examine the rock at varying layers. Results from those grindings are currently being analyzed.

    The image mosaic is about 6 centimeters (2.4 inches) across.

  8. Meet Jen Kurtz | NREL

    Science.gov Websites

    Denver. But truthfully, the group manager in NREL's hydrogen and fuel cells systems engineering group --are successful." Jen says that one of the biggest things in the mission space is that research around hydrogen infrastructure will help enable more than one advancement. "We want to increase

  9. PREFACE: Festschrift to mark the sixtieth birthday of Professor Jens Lothe

    NASA Astrophysics Data System (ADS)

    Jøssang, Torstein; Barnett, David M.

    1992-01-01

    The collection of papers in this Festschrift represents the proceedings of a symposium held at the Norwegian Academy of Science and Letters on November 25-26, 1991, marking the occasion of the sixtieth birthday of Professor Jens Lothe. The symposium organizers attempted to invite contributors, either written, oral, or both, from a group of international scientists who have either collaborated with Jens in the past or whose work has had a significant impact in one of three areas in which Jens has focussed his own research interests, namely, statistical physics, elasticity and elastic waves, and the theory of dislocations in crystalline solids. The extent to which we have succeeded in obtaining a proper spectrum of contributors and contributions must be judged by the readers of this volume. It is rather rare in modern times to encounter a physicist such as Jens who has made seminal contributions in fields as diverse as the three included in this Festschrift. For this reason it is both historically interesting and instructive to follow the path that Jens Lothe's research career has taken him, since doing so clearly points out the international nature of the scientific endeavor and the fact that the search for scientific truth transcends national borders and governmental ideologies. Jens' postdoctoral studies at the University of Bristol in the late 1950s brought him in contact with an American postdoctoral student, John Hirth, who had worked on nucleation theory and condensation under the late Professor G M Pound at Carnegie-Mellon University. (Alex Maradudin, one of the contributors to the surface wave session of this symposium was also a postdoctoral fellow at Bristol at this time.) Both Lothe and Hirth had come to Bristol to acquaint themselves with dislocation theory; their first joint paper on double-kink nucleation theory was followed by numerous joint efforts, including their now-classic book Theory of Dislocations. Clearly, their interaction jelled. As legend

  10. AntiJen: a quantitative immunology database integrating functional, thermodynamic, kinetic, biophysical, and cellular data

    PubMed Central

    Toseland, Christopher P; Clayton, Debra J; McSparron, Helen; Hemsley, Shelley L; Blythe, Martin J; Paine, Kelly; Doytchinova, Irini A; Guan, Pingping; Hattotuwagama, Channa K; Flower, Darren R

    2005-01-01

    AntiJen is a database system focused on the integration of kinetic, thermodynamic, functional, and cellular data within the context of immunology and vaccinology. Compared to its progenitor JenPep, the interface has been completely rewritten and redesigned and now offers a wider variety of search methods, including a nucleotide and a peptide BLAST search. In terms of data archived, AntiJen has a richer and more complete breadth, depth, and scope, and this has seen the database increase to over 31,000 entries. AntiJen provides the most complete and up-to-date dataset of its kind. While AntiJen v2.0 retains a focus on both T cell and B cell epitopes, its greatest novelty is the archiving of continuous quantitative data on a variety of immunological molecular interactions. This includes thermodynamic and kinetic measures of peptide binding to TAP and the Major Histocompatibility Complex (MHC), peptide-MHC complexes binding to T cell receptors, antibodies binding to protein antigens and general immunological protein-protein interactions. The database also contains quantitative specificity data from position-specific peptide libraries and biophysical data, in the form of diffusion co-efficients and cell surface copy numbers, on MHCs and other immunological molecules. The uses of AntiJen include the design of vaccines and diagnostics, such as tetramers, and other laboratory reagents, as well as helping parameterize the bioinformatic or mathematical in silico modeling of the immune system. The database is accessible from the URL: . PMID:16305757

  11. JEN-1 Reactor Control System; SISTEMA DE CONTROL DEL REACTOR JEN-1

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cantillo, M.F.; Nuno, C.M.; Andreu, J.L.M.

    1963-01-01

    ABS>The JEN-1 3Mw power swimming pool reactor electrical control circuits are described. Start-up, power generation in the core, and shutdown are controlled by the reactor control system. This control system guarantees in each moment the safety conditions during reactor operation. Each circuit was represented by a scheme, complemented with a description of its function, components, and operation theory. Components described include: scram circuit; fission counter control circuit; servo control circuit; control circuit of safety sheets; control circuits of primary, secondary, and clean-up pump motors and tower fan motor; primary valve motor circuit; center cubicle alarm circuit; and process alarm circuit.more » (auth)« less

  12. Levey-Jennings Analysis Uncovers Unsuspected Causes of Immunohistochemistry Stain Variability.

    PubMed

    Vani, Kodela; Sompuram, Seshi R; Naber, Stephen P; Goldsmith, Jeffrey D; Fulton, Regan; Bogen, Steven A

    Almost all clinical laboratory tests use objective, quantitative measures of quality control (QC), incorporating Levey-Jennings analysis and Westgard rules. Clinical immunohistochemistry (IHC) testing, in contrast, relies on subjective, qualitative QC review. The consequences of using Levey-Jennings analysis for QC assessment in clinical IHC testing are not known. To investigate this question, we conducted a 1- to 2-month pilot test wherein the QC for either human epidermal growth factor receptor 2 (HER-2) or progesterone receptor (PR) in 3 clinical IHC laboratories was quantified and analyzed with Levey-Jennings graphs. Moreover, conventional tissue controls were supplemented with a new QC comprised of HER-2 or PR peptide antigens coupled onto 8 μm glass beads. At institution 1, this more stringent analysis identified a decrease in the HER-2 tissue control that had escaped notice by subjective evaluation. The decrement was due to heterogeneity in the tissue control itself. At institution 2, we identified a 1-day sudden drop in the PR tissue control, also undetected by subjective evaluation, due to counterstain variability. At institution 3, a QC shift was identified, but only with 1 of 2 controls mounted on each slide. The QC shift was due to use of the instrument's selective reagent drop zones dispense feature. None of these events affected patient diagnoses. These case examples illustrate that subjective QC evaluation of tissue controls can detect gross assay failure but not subtle changes. The fact that QC issues arose from each site, and in only a pilot study, suggests that immunohistochemical stain variability may be an underappreciated problem.

  13. Wirtgen Remixer surface recycling U.S. 90 Jennings, LA. : construction report.

    DOT National Transportation Integrated Search

    1991-02-01

    This report documents the surface recycling of 7.4 miles of route U.S. 90 from the junction of La 99 to Jennings, Louisiana. The specialized recycling equipment was provided and operated by Remixer Contracting Co., Inc. of Austin, Texas. Roadway prod...

  14. The Ronnie Gardiner Rhythm and Music Method - a feasibility study in Parkinson's disease.

    PubMed

    Pohl, Petra; Dizdar, Nil; Hallert, Eva

    2013-01-01

    To assess the feasibility of the novel intervention, Ronnie Gardiner Rhythm and Music (RGRM™) Method compared to a control group for patients with Parkinson's disease (PD). Eighteen patients, mean age 68, participating in a disability study within a neurological rehabilitation centre, were randomly allocated to intervention group (n = 12) or control group (n = 6). Feasibility was assessed by comparing effects of the intervention on clinical outcome measures (primary outcome: mobility as assessed by two-dimensional motion analysis, secondary outcomes: mobility, cognition, quality of life, adherence, adverse events and eligibility). Univariable analyses showed no significant differences between groups following intervention. However, analyses suggested that patients in the intervention group improved more on mobility (p = 0.006), cognition and quality of life than patients in the control group. There were no adverse events and a high level of adherence to therapy was observed. In this disability study, the use of the RGRM™ Method showed promising results in the intervention group and the adherence level was high. Our results suggest that most assessments chosen are eligible to use in a larger randomized controlled study for patients with PD. The RGRM™ Method appeared to be a useful and safe method that showed promising results in both motor and cognitive functions as well as quality of life in patients with moderate PD. The RGRM™ Method can be used by physiotherapists, occupational, speech and music therapists in neurological rehabilitation. Most measurements were feasible except for Timed-Up-and-Go.

  15. [Jennings Randolph Forum (3rd, Washington, District of Columbia, May 20-22, 1984).

    ERIC Educational Resources Information Center

    CAC Citizenship Education News, 1984

    1984-01-01

    This overview of the third annual Jennings Randolph Forum focuses on the role that election campaigns and the political process are capable of playing in citizenship education. Council for the Advancement of Citizenship (CAC) testimony on citizenship education follows a general overview of the conference proceedings. A set of mandates for…

  16. William Jennings Bryan: Boy Orator, Broken Man and the "Evolution" of America's Public Philosophy

    ERIC Educational Resources Information Center

    Murphy, Troy A.

    2002-01-01

    Perhaps more than any other figure in American history, William Jennings Bryan is remembered for specific and identifiable moments of rhetorical action: the much-revered 1896 "Cross of gold" speech and the much-maligned Scopes "monkey trial" of 1925. The dissonance between these two events, at least with respect to the ways in…

  17. Toward a Pragmatist Epistemology: Arthur O. Lovejoy's and H. S. Jennings's Biophilosophical Responses to Neovitalism, 1909-1914.

    PubMed

    Russell, Doug

    2015-01-01

    The sustained interdisciplinary debate about neovitalism between two Johns Hopkins University colleagues, philosopher Arthur O. Lovejoy and experimental geneticist H. S. Jennings, in the period 1911-1914, was the basis for their theoretical reconceptualization of scientific knowledge as contingent and necessarily incomplete in its account of nature. Their response to Hans Driesch's neovitalist concept of entelechy, and his challenge to the continuity between biology and the inorganic sciences, resulted in a historically significant articulation of genetics and philosophy. This study traces the debate's shift of problem-focus away from neovitalism's threat to the unity of science - "organic autonomy," as Lovejoy put it - and toward the potential for development of a nonmechanististic, nonrationalist theory of scientific knowledge. The result was a new pragmatist epistemology, based on Lovejoy's and Jennings's critiques of the inadequacy of pragmatism's account of scientific knowledge. The first intellectual move, drawing on naturalism and pragmatism, was based on a reinterpretation of science as organized experience. The second, sparked by Henri Bergson's theory of creative evolution, and drawing together elements of Dewey's and James's pragmatisms, produced a new account of the contingency and necessary incompleteness of scientific knowledge. Prompted by the neovitalists' mix of a priori concepts and, in Driesch's case, and adherence to empiricism, Lovejoy's and Jennings's developing pragmatist epistemologies of science explored the interrelation between rationalism and empiricism.

  18. Reflecting on Jens Rasmussen's legacy (2) behind and beyond, a 'constructivist turn'.

    PubMed

    Le Coze, Jean-Christophe

    2017-03-01

    This article is the second part of a study on the legacy of Jens Rasmussen. The first article, subtitled 'A Strong Program for a Hard Problem', looks back on his 30 years of scientific contribution, from 1969 to 2000. This second article explores and investigates some of the intellectual roots which influenced his thinking, using them as a basis to understand some limits and move forward. Indeed, historically oriented studies such as this one are not only tributes to researchers, but a way to differentiate and contrast our present situation with the past in order to integrate contemporary trends, be they theoretical or empirical, or oriented towards research and new models. In the first section of this article, I offer a synthesis of the background covered in the previous article, but I use a tree here as a graphical complement. Branches of the tree show the many fruitful directions opened by Jens Rasmussen, directions which inspired many researchers. In the second part, I address what I believe to be behind this wealth of engineering legacy: cybernetics. I contend that cybernetics has had a profound influence on his thinking and provided him key principles for his inspiring and successful models. To develop the tree image, one might say that cybernetics is the trunk of the tree. Finally, in the third part, I take the opportunity to explore the relevance of extending and sensitising his program to constructivist discourses. After an introduction to this discourse, identifying four types of constructivisms (cognitive, social, epistemological and anthropological), I characterise this move as a 'constructivist turn'. Copyright © 2015 Elsevier Ltd. All rights reserved.

  19. The effect of some organic substances on the mycelium of the fungus Ustilago nuda (Jens.) Rostr.

    PubMed

    Krátká, J

    1976-01-01

    Research was performed for studying the effect of some organic compounds, considered by many authors as the products ob barley seed metabolism generated after anaerobic seed treatment, on the mycelium of the fungus Ustilago nuda (Jens.) Rostr. The author examined the effectiveness of ethylacohol, acetaldehyde, acetic acid, succinic acid, lactic acid, and hydroquinone in concentrations from 1 M to 10(-6) M, and the effectiveness of extracts from disinfected seeds in doses from 10 g to 0.001 g/l. The effect of the mentioned solutions was examined as exerted on the growth of dicaryotic mycelium and on the growth of the haploid promycelium of the fungus. The dicaryotic mycelium of Ustilago nuda (Jens.) Rostr. was cultivated on potato agar with benzoic acid. The presence of the acid prevents mitosis, and the chlamydospores germinate on the nutritive medium with two fibres having binuclear cells. The haploid promycelium was cultivated on potato agar; chlamydospores germinated with one four-cell fibre, and individual cells are mononuclear and haploid. Only later, a dicarytic mycelium is created in a complex process. In all the substances used, the concentration of 1 M was found to stop further growth of mycelium. The concentration of 10(-1) M of acetic acid and hydroquinone also stopped growth, the same concentration of acetaldehyde, lactic acid, succinic acid, ethylacohol stimulated mycelium growth in comparison with the control. The concentration of 10(-6) M stimulated mycelium growth in a majority of cases. Extracts from disinfected seeds did not influence mycelium growth significantly in all cases in comparison with the control. The results were similar in the two types of mycelium.

  20. Materials Research in Support of Superconducting Machinery V

    DTIC Science & Technology

    1976-04-01

    GTAW , EB, GMAW), brazing, and soldering from 4-300 K. Properties include tensile, notched tensile, fracture toughness, and fatigue crack growth...include: aluminum alloys 1100, 2014, 2219; a nicke1- chromium -iron alloy; iron-47.5 nickel; and the composite materials boron/aluminum, boron/epoxy, S...nickel" by H. M. Ledbetter and D. T. Read. (3) N. jkel- chromium -iron-molybdenum alloy. There is an accompanying reprint of our previously described

  1. Supporting the human life-raft in confronting the juggernaut of technology: Jens Rasmussen, 1961-1986.

    PubMed

    Kant, Vivek

    2017-03-01

    Jens Rasmussen's contribution to the field of human factors and ergonomics has had a lasting impact. Six prominent interrelated themes can be extracted from his research between 1961 and 1986. These themes form the basis of an engineering epistemology which is best manifested by his abstraction hierarchy. Further, Rasmussen reformulated technical reliability using systems language to enable a proper human-machine fit. To understand the concept of human-machine fit, he included the operator as a central component in the system to enhance system safety. This change resulted in the application of a qualitative and categorical approach for human-machine interaction design. Finally, Rasmussen's insistence on a working philosophy of systems design as being a joint responsibility of operators and designers provided the basis for averting errors and ensuring safe and correct system functioning. Copyright © 2016 Elsevier Ltd. All rights reserved.

  2. Multi-INT and Information Operations Simulation and Training Technologies (MIISTT)

    DTIC Science & Technology

    2010-11-01

    Communications Ronnie F. Silber Lockheed Martin Raymond T. Tillman L-3 Communications November 2010 Final Report DISTRIBUTION A. Approved...of information, including suggestions for reducing this burden to Department of Defense, Washington Headquarters Services , Directorate for...Michelle Caisse, Ronnie F. Silber , Raymond T. Tillman 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 2830HXA1 7. PERFORMING

  3. National Dam Inspection Program. Jennings Pond Dam (NDI I.D. PA-0891 DER I.D. 066-012) Susquehanna River Basin, Little Mehoopany Creek, Wyoming County, Pennsylvania. Phase I Inspection Report,

    DTIC Science & Technology

    1981-03-19

    Area 7.9 square miles(1) b. Discharge at Dam Site ( cfs ) Maximum known flood at dam site Unknown Outlet conduit at maximum pool Unknown Gated spillway...700 cfs , based on the available 2.4-foot freeboard relative to the low spot on the left abutment. b. Experience Data. As previously stated, Jennings...in Appendix D. The inflow hydrograph for one-half PMF was found to have a peak flow of 6835 cfs . Computer input and summary of computer output are

  4. Graphical and statistical techniques for cardiac cycle time (phase) dependent changes in interbeat interval: problems with the Jennings et al. (1991) proposals.

    PubMed

    Barry, R J

    1993-01-01

    Two apparently new effects in human cardiac responding, "primary bradycardia" and "vagal inhibition", were first described by the Laceys. These effects have been considered by some researchers to reflect differential cardiac innervation, analogous to similar effects observed in animal preparations with direct vagal stimulation. However, it has been argued that such effects arise merely from the data-analytic techniques introduced by the Laceys, and hence are not genuine cardiac cycle effects. Jennings, van der Molen, Somsen and Ridderinkhoff (Psychophysiology, 28 (1991) 596-606) recently proposed a plotting technique and statistical procedure in an attempt to resolve this issue. The present paper demonstrates that the plotting technique fails to achieve their stated aim, since it identifies data from identical cardiac responses as showing cardiac-cycle effects. In addition, the statistical procedure is shown to be reducible to a trivial test of response occurrence. The implication of these demonstrations, in the context of other work, is that this area of investigation has reached a dead end.

  5. Jens Esmark's Christiania (Oslo) meteorological observations 1816-1838: the first long-term continuous temperature record from the Norwegian capital homogenized and analysed

    NASA Astrophysics Data System (ADS)

    Hestmark, Geir; Nordli, Øyvind

    2016-11-01

    In 2010 we rediscovered the complete set of meteorological observation protocols made by Jens Esmark (1762-1839) during his years of residence in the Norwegian capital of Oslo (then Christiania). From 1 January 1816 to 25 January 1839, Esmark at his house in Øvre Voldgate in the morning, early afternoon and late evening recorded air temperature with state-of-the-art thermometers. He also noted air pressure, cloud cover, precipitation and wind directions, and experimented with rain gauges and hygrometers. From 1818 to the end of 1838 he twice a month provided weather tables to the official newspaper Den Norske Rigstidende, and thus acquired a semi-official status as the first Norwegian state meteorologist. This paper evaluates the quality of Esmark's temperature observations and presents new metadata, new homogenization and analysis of monthly means. Three significant shifts in the measurement series were detected, and suitable corrections are proposed. The air temperature in Oslo during this period is shown to exhibit a slow rise from 1816 towards 1825, followed by a slighter fall again towards 1838.

  6. Carboxylic acids permeases in yeast: two genes in Kluyveromyces lactis.

    PubMed

    Lodi, Tiziana; Fontanesi, Flavia; Ferrero, Iliana; Donnini, Claudia

    2004-09-15

    Two new genes KlJEN1 and KlJEN2 were identified in Kluyveromyces lactis. The deduced structure of their products is typical of membrane-bound carriers and displays high similarity to Jen1p, the monocarboxylate permease of Saccharomyces cerevisiae. Both KlJEN1 and KlJEN2 are under the control of glucose repression mediated by FOG1 and FOG2, corresponding to S. cerevisiae GAL83 and SNF1 respectively, and KlCAT8, proteins involved in glucose signalling cascade in K. lactis. KlJEN1, but not KlJEN2, is induced by lactate. KlJEN2 in contrast is expressed at high level in ethanol and succinate. The physiological characterization of null mutants showed that KlJEN1 is the functional homologue of ScJEN1, whereas KlJEN2 encodes a dicarboxylic acids transporter. In fact, KlJen1p [transporter classification (TC) number: 2.A.1.12.2.] is required for lactate uptake and therefore for growth on lactate. KlJen2p is required for succinate transport, as demonstrated by succinate uptake experiments and by inability of Kljen2 mutant to grow on succinate. This carrier appears to transport also malate and fumarate because the Kljen2 mutant cannot grow on these substrates and the succinate uptake is competed by these carboxylic acids. We conclude that KlJEN2 is the first yeast gene shown to encode a dicarboxylic acids permease.

  7. 75 FR 27623 - Qualification of Drivers; Exemption Applications; Vision

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-17

    .... Askin, Paul J. Bannon, Ernie E. Black, Ronnie F. Bowman, Gary O. Brady, Stephen H. Goldcamp, Steven F. Grass, Wai F. King, Dennis E. Krone, Richard J. McKenzie, Jr., Christopher J. Meerten, Craig W. Miller...

  8. 75 FR 38603 - Qualification of Drivers; Exemption Renewals; Vision

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-02

    ... James C. Askin, Paul J. Bannon, Ernie E. Black, Ronnie F. Bowman, Gary O. Brady, Stephen H. Goldcamp, Steven F. Grass, Wai F. King, Dennis E. Krone, Richard J. McKenzie, Jr., Christopher J. Meerten, Craig W...

  9. Correction to: Applicability and accuracy of pretest probability calculations implemented in the NICE clinical guideline for decision making about imaging in patients with chest pain of recent onset.

    PubMed

    Roehle, Robert; Wieske, Viktoria; Schuetz, Georg M; Gueret, Pascal; Andreini, Daniele; Meijboom, Willem Bob; Pontone, Gianluca; Garcia, Mario; Alkadhi, Hatem; Honoris, Lily; Hausleiter, Jörg; Bettencourt, Nuno; Zimmermann, Elke; Leschka, Sebastian; Gerber, Bernhard; Rochitte, Carlos; Schoepf, U Joseph; Shabestari, Abbas Arjmand; Nørgaard, Bjarne; Sato, Akira; Knuuti, Juhani; Meijs, Matthijs F L; Brodoefel, Harald; Jenkins, Shona M M; Øvrehus, Kristian Altern; Diederichsen, Axel Cosmus Pyndt; Hamdan, Ashraf; Halvorsen, Bjørn Arild; Rodriguez, Vladimir Mendoza; Wan, Yung Liang; Rixe, Johannes; Sheikh, Mehraj; Langer, Christoph; Ghostine, Said; Martuscelli, Eugenio; Niinuma, Hiroyuki; Scholte, Arthur; Nikolaou, Konstantin; Ulimoen, Geir; Zhang, Zhaoqi; Mickley, Hans; Nieman, Koen; Kaufmann, Philipp A; Buechel, Ronny Ralf; Herzog, Bernhard A; Clouse, Melvin; Halon, David A; Leipsic, Jonathan; Bush, David; Jakamy, Reda; Sun, Kai; Yang, Lin; Johnson, Thorsten; Laissy, Jean-Pierre; Marcus, Roy; Muraglia, Simone; Tardif, Jean-Claude; Chow, Benjamin; Paul, Narinder; Maintz, David; Hoe, John; de Roos, Albert; Haase, Robert; Laule, Michael; Schlattmann, Peter; Dewey, Marc

    2018-06-01

    The original version of this article, published on 19 March 2018, unfortunately contained a mistake. The following correction has therefore been made in the original: The names of the authors Philipp A. Kaufmann, Ronny Ralf Buechel and Bernhard A. Herzog were presented incorrectly.

  10. Students.edu: Guidelines for Online Education Programs.

    ERIC Educational Resources Information Center

    Lane-Maher, Maureen; Ashar, Hanna

    2001-01-01

    Suggests that higher education administrators can learn from the emerging practices of electronic commerce. Adapting a model laid out by Patricia Seybold with Ronni Marshak in "Customers.com," provides administrative guidelines for online education programs that combine sound business practice with information technology to make it easy for…

  11. 75 FR 60861 - Qualification of Drivers; Exemption Renewals; Vision

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-01

    ..., Riche Ford, Kelly L. Foster, Kevin J. Friedel, Donald W. Garner, Paul W. Goebel, Jr., Ronnie L. Hanback... J. Lewis, Velmer L. McClelland, Larry McCoy, Sr., Robert W. McMillian, Danny W. Nuckles, Richard A..., Robert M. Stewart, John L. Stone, Nils S. Thornberg, Daniel W. Toppings, Kenneth E. Valentine...

  12. 75 FR 44050 - Qualification of Drivers; Exemption Applications; Vision

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-27

    ..., Donald W. Garner, Paul W. Goebel, Jr., Ronnie L. Hanback, Steven G. Harter, Michael C. Hensley, George F..., Andrew C. Kelly, Jason W. King, James T. Leek, Billy J. Lewis, Velmer L. McClelland, Larry McCoy, Sr.... Thornberg, Daniel W. Toppings, Kenneth E. Valentine, Christopher R. Whitson, and George L. Young. The...

  13. 76 FR 34127 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-10

    ... diabetic retinopathy. He holds a Class A Commercial Drivers License from Illinois. Ronnie E. Combs, Jr. Mr... have diabetic retinopathy. He holds a Class A CDL from Kentucky. Barbara A. Farrell Ms. Farrell, 42... have diabetic retinopathy. She holds a Class A CDL from Washington. Tony D. Gayles Mr. Gayles, 50, has...

  14. KSC-04PD-2637

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. Kennedys Deputy Director Woodrow Whitlow Jr. presents Ronny Goodin an award for a winning entry in the NASA Values essay contest. The award was presented during the One NASA Leader-Led Workshop, which presented senior leadership in the Agency talking about ongoing Transformation activities and Kennedys role in the Vision for Space Exploration.

  15. The α-Arrestin Bul1p Mediates Lactate Transporter Endocytosis in Response to Alkalinization and Distinct Physiological Signals.

    PubMed

    Talaia, Gabriel; Gournas, Christos; Saliba, Elie; Barata-Antunes, Cláudia; Casal, Margarida; André, Bruno; Diallinas, George; Paiva, Sandra

    2017-11-24

    Eukaryotic α-arrestins connect environmental or stress signaling pathways to the endocytosis of plasma membrane transporters or receptors. The Saccharomyces cerevisiae lactate transporter Jen1p has been used as a model cargo for elucidating the mechanisms underlying endocytic turnover in response to carbon sources. Here, we discover a novel pathway of Jen1p endocytosis mediated by the α-arrestin Bul1p in response to the presence of cycloheximide or rapamycin, or prolonged growth in lactate. While cycloheximide or rapamycin modify cells pleiotropically, the major effect of prolonged growth in lactate was shown to be external pH alkalinization. Importantly, employment of specific inactive Jen1p versions showed that Bul1p-dependent endocytosis requires lactate transport, according to the signal imposed. Our results support a model where conformational changes of Jen1p, associated with substrate/H + symport, are critical for the efficiency of Bul1p-dependent Jen1p turnover. Copyright © 2017 Elsevier Ltd. All rights reserved.

  16. KENNEDY SPACE CENTER, FLA. - The Honorable Toni Jennings (left), lieutenant governor of the state of Florida, and Frank T. Brogan, president of Florida Atlantic University, receive a briefing on the research that will be conducted in the Space Life Sciences Lab from Dr. Robert J. Ferl (right), director of Space Agriculture Biotechnology Research and Education (SABRE), University of Florida. Jennings and Brogan are speaking at a dedication and ribbon-cutting ceremony for the lab hosted by NASA-Kennedy Space Center and the state of Florida at the new lab. Completed in August, the facility encompasses more than 100,000 square feet and was formerly known as the Space Experiment Research and Processing Laboratory or SERPL. The state, through the Florida Space Authority, built the research lab which is host to NASA, NASA’s Life Sciences Services contractor Dynamac Corp., Bionetics Corp., and researchers from the University of Florida. Dynamac Corp. leases the facility. The Florida Space Research Institute is responsible for gaining additional tenants from outside the NASA community.

    NASA Image and Video Library

    2003-11-19

    KENNEDY SPACE CENTER, FLA. - The Honorable Toni Jennings (left), lieutenant governor of the state of Florida, and Frank T. Brogan, president of Florida Atlantic University, receive a briefing on the research that will be conducted in the Space Life Sciences Lab from Dr. Robert J. Ferl (right), director of Space Agriculture Biotechnology Research and Education (SABRE), University of Florida. Jennings and Brogan are speaking at a dedication and ribbon-cutting ceremony for the lab hosted by NASA-Kennedy Space Center and the state of Florida at the new lab. Completed in August, the facility encompasses more than 100,000 square feet and was formerly known as the Space Experiment Research and Processing Laboratory or SERPL. The state, through the Florida Space Authority, built the research lab which is host to NASA, NASA’s Life Sciences Services contractor Dynamac Corp., Bionetics Corp., and researchers from the University of Florida. Dynamac Corp. leases the facility. The Florida Space Research Institute is responsible for gaining additional tenants from outside the NASA community.

  17. The Fundamental Chemistry and Physics of Munitions under Extreme Conditions

    DTIC Science & Technology

    2011-02-01

    I. I. Oleynik, S. V. Zybin, and C. T. White, “Density Functional Theory Calculations of Solid Nitromethane under Hydrostatic and Uniaxial...White (NRL), Ivan Oleynik (USF): anisotropic nonlinear elasticity and equations of states of crystalline EM (PETN, RDX, HMX, TATB, nitromethane ...and nitromethane ;  Aidan Thompson (SNL): shock-to-detonation transition in PETN and CL-20;  Ronnie Kosloff (Hebrew University of Jerusalem

  18. Dictionary of Cancer Terms

    MedlinePlus

    ... causes the cancer cells to grow. Also called AR. androgen receptor positive listen (AN-droh-jen reh- ... binding and actions of androgen hormones. Also called AR+. androgen suppression listen (AN-droh-jen suh-PREH- ...

  19. Development of Efficient Charge-Selective Materials for Bulk Heterojunction Polymer Solar Cells

    DTIC Science & Technology

    2015-01-15

    Cho, D. S. Ginger and A. K. Y. Jen, Advanced Materials, 2014, 26, 6262-6267. 17. N. Cho, C.-Z. Li, H.-L. Yip and A. K. Y. Jen, Energy...Solar Cells”, Adv. Funct. Mater. 2015, ASAP. 4. J. H. Kim, P. W. Liang, S. T. Williams, N. C. Cho, C. C. Chueh, M. S. Glaz, D. S. Ginger , A. K.-Y...Kim, P. W. Liang, S. T. Williams, N. C. Cho, C. C. Chueh, M. S. Glaz, D. S. Ginger , A. K.-Y. Jen, 2015, ASAP. 7. P. W. Liang, C. C. Chueh, X. K

  20. Survey of Small Business Barriers to Department of Defense Contracts

    DTIC Science & Technology

    2017-01-01

    Survey of SMALL BUSINESS BARRIERS to DEPARTMENT of DEFENSE CONTRACTS Ronnie Schilling, Thomas A. Mazzuchi, and Shahram Sarkani A key tenet of...success in retaining small businesses and meeting small business contracting goals. Results of a survey given to 681 small business leaders show many...2017, Vol. 24 No. 1 : 2–29 Survey of Small Business Barriers to DoD Contracts http://www.dau.mil Creating more than half of this country’s gross

  1. Defense Acquisition Research Journal. Volume 24, Number 1, Issue 80

    DTIC Science & Technology

    2017-01-01

    aol.com. ISSUE 80 JANUARY 2017 VOL. 24 NO. 1 1 We’re on the Web at: http://www.dau.mil/publications/DefenseARJ/default.aspx and http...central website that would help facilitate teaming among complementary small businesses. • For technical proposals, use white papers as an initial screen...Engineering from The University of Alabama in Huntsville. (E-mail address: ronnie.schilling@mda.mil) Dr. Thomas A . Mazzuchi is cha ir of the Department

  2. Cognitive Work Analysis: Foundations, Extensions, and Challenges

    DTIC Science & Technology

    2011-11-01

    1 . Introduction A quarter of a century has passed since Jens Rasmussen published his first...achievements is the development of the cognitive work analysis framework itself, which has its origins in the work of Jens Rasmussen and his colleagues...intentionally blank UNCLASSIFIED DSTO-GD-0680 Contents 1 . INTRODUCTION

  3. Edward W. Jennings | NREL

    Science.gov Websites

    practices promoting a safe and supportive working environment. His research interests include environmental, safety, and health (ESH) and facility issues, he is responsible for implementing safe work plan; working directly with awardees by performing on-site validations to collect and analyze enzyme

  4. Late Bilinguals Share Syntax Unsparingly between L1 and L2: Evidence from Crosslinguistically Similar and Different Constructions

    ERIC Educational Resources Information Center

    Hwang, Heeju; Shin, Jeong-Ah; Hartsuiker, Robert J.

    2018-01-01

    Languages often use different constructions to convey the same meaning. For example, the meaning of a causative construction in English ("Jen had her computer fixed") is conveyed using an active structure in Korean ("Jen-NOM her computer-ACC fixed"), and yet little is known about how bilinguals represent and process such…

  5. Are Right Wing Extremists in Scandinavia a Threat to Government Personnel and the Societal Mainstream? A Prognosis.

    DTIC Science & Technology

    2001-04-12

    football teams and pop groups make appeals in order to awaken the politicians and the public to the threat. Moreover, numerous episodes from the...Öhman, was killed by a handful of immigrants, and almost at the same time neo-Nazis killed a punk , Ronny Landin. The persons convicted of killing the...terms the person killing the neo-Nazi, while doing the opposite concerning the neo-Nazi killing the punk . In other words, in one case the perpetrators

  6. Integrated control of transporter endocytosis and recycling by the arrestin-related protein Rod1 and the ubiquitin ligase Rsp5.

    PubMed

    Becuwe, Michel; Léon, Sébastien

    2014-11-07

    After endocytosis, membrane proteins can recycle to the cell membrane or be degraded in lysosomes. Cargo ubiquitylation favors their lysosomal targeting and can be regulated by external signals, but the mechanism is ill-defined. Here, we studied the post-endocytic trafficking of Jen1, a yeast monocarboxylate transporter, using microfluidics-assisted live-cell imaging. We show that the ubiquitin ligase Rsp5 and the glucose-regulated arrestin-related trafficking adaptors (ART) protein Rod1, involved in the glucose-induced internalization of Jen1, are also required for the post-endocytic sorting of Jen1 to the yeast lysosome. This new step takes place at the trans-Golgi network (TGN), where Rod1 localizes dynamically upon triggering endocytosis. Indeed, transporter trafficking to the TGN after internalization is required for their degradation. Glucose removal promotes Rod1 relocalization to the cytosol and Jen1 deubiquitylation, allowing transporter recycling when the signal is only transient. Therefore, nutrient availability regulates transporter fate through the localization of the ART/Rsp5 ubiquitylation complex at the TGN.

  7. A Qualitative Look at Leisure Benefits for Taiwanese Nursing Students

    ERIC Educational Resources Information Center

    Hsieh, Shwu-Ching; Spaulding, Angela; Riney, Mark

    2004-01-01

    The purpose of this study was to determine attitudes of first year nursing students toward leisure participation at the Jen-Te Junior College of Medicine Nursing and Management in Miao-Li, Taiwan. The three research questions used for this study were: What types of leisure activities do first year nursing students at Jen-Te Junior College…

  8. Where Violence Lives: Notes for a Pedagogy of Aftermath

    ERIC Educational Resources Information Center

    Jennings, Willie James

    2015-01-01

    In this article Willie James Jennings opens this discussion by noting that he lives in the midst of a North Carolina gun culture, the intensity of which is quite overwhelming. He asks how we might educate against the specific seductive powers of the weapon and especially the gun? As an educator, Jennings believes that clearly, the unmaking of…

  9. Expected Position Error for an Onboard Satellite GPS Receiver

    DTIC Science & Technology

    2015-03-01

    Committee Membership: Dr. Alan Jennings, PhD Chairman Dr. Eric D. Swenson, Ph.D. Member Dr. Marshall E. Haker , Ph.D. Member AFIT-ENY-MS-15-M-029 Abstract...acknowledge both Dr. Jennings and Maj Haker for taking on the role of being my advisor and as well as committee member at various times during this

  10. Mitochondrial Genomics and Northwestern Atlantic Population Genetics of Marine Annelids

    DTIC Science & Technology

    2005-09-01

    surfclams , Spisula solidissima, in the western North Atlantic based on mitochondrial and nuclear DNA sequences. Marine Biology, 146: 707-716. Hayden BP...Science 1930 and Engineering DOCTORAL DISSERTATION Mitochondrial Genomics and Northwestern Atlantic Population Genetics of Marine Annelids by Robert M...Jennings September 2005 MITIWHOI 2005-15 Mitochondrial Genomics and Northwestern Atlantic Population Genetics of Marine Annelids by Robert M. Jennings

  11. Using a Tracking System to Improve Prostate Cancer Screening and Follow-up in a Small Urban Community

    DTIC Science & Technology

    2001-05-01

    clinical practice, attention is directed toward informing the general public about them. In the late 1980 ’s, the Prostate Cancer Education Council...impact of abnormal mammograms on psychosocial outcomes and subsequent screening. PsychoOncology, 9, 402-410. Myers, R.E., Hyslop T., Jennings-Dozier, K...impact of abnormal mammograms on psychosocial outcomes and subsequent screening. PsychoOncology, 9, 402- 410. Myers, R.E., Hyslop T., Jennings-Dozier, K

  12. Nine Years of Cooperation: The US-German Memorandum of Understanding (MoU) on Helicopter Aeromechanics 2003-2012

    DTIC Science & Technology

    2013-12-01

    Hamers , Mario, Lantzsch, Robin, Wolfram, Jens: First Control System Evalua- tion of the Research Helicopter FHS, 33rd European Rotorcraft Forum, Kazan...62nd Annual Forum of the AHS, Phoenix, AZ, 2006 [65] Brenner, Hanno, Hamers , Mario: Preparatory Activities for CH-53 Flight Tests with a Slung...Wolfram, Jens, Hamers , Mario: Increasing Handling Qualities and Flight Control Performance using an Air Resonance Controller. 64th Annual Forum of

  13. Jen Gustetic visits Swamp Works

    NASA Image and Video Library

    2016-10-28

    Jenn Gustetic, NASA's Small Business Innovation Research Program executive, talks with Rob Mueller, senior technologist and co-founder of Kennedy Space Center's Swamp Works. Gustetic met team members and viewed many of the pioneering technologies and innovations in development at Kennedy. Swamp Works is a hands-on, lean development environment for innovation following the philosophies pioneered in Kelly Johnson's Skunk Works and Werner von Braun's development shops. The Swamp Works establishes rapid, innovative and cost-effective exploration mission solutions through a highly collaborative, "no walls" approach, leveraging partnerships across NASA, industry and academia.

  14. 'Diamond' in 3-D

    NASA Technical Reports Server (NTRS)

    2004-01-01

    This 3-D, microscopic imager mosaic of a target area on a rock called 'Diamond Jenness' was taken after NASA's Mars Exploration Rover Opportunity ground into the surface with its rock abrasion tool for a second time.

    Opportunity has bored nearly a dozen holes into the inner walls of 'Endurance Crater.' On sols 177 and 178 (July 23 and July 24, 2004), the rover worked double-duty on Diamond Jenness. Surface debris and the bumpy shape of the rock resulted in a shallow and irregular hole, only about 2 millimeters (0.08 inch) deep. The final depth was not enough to remove all the bumps and leave a neat hole with a smooth floor. This extremely shallow depression was then examined by the rover's alpha particle X-ray spectrometer.

    On Sol 178, Opportunity's 'robotic rodent' dined on Diamond Jenness once again, grinding almost an additional 5 millimeters (about 0.2 inch). The rover then applied its Moessbauer spectrometer to the deepened hole. This double dose of Diamond Jenness enabled the science team to examine the rock at varying layers. Results from those grindings are currently being analyzed.

    The image mosaic is about 6 centimeters (2.4 inches) across.

  15. Detection of Human Fatigue

    DTIC Science & Technology

    2005-08-05

    research (Lacey, 1974; Jennings, 1992; van der Molen , 2000; Somsen, 2004) using principally fixed foreperiod reaction time tasks demonstrated that in...U.S. Department of Transportation DOT/FAA/AM-99/28. Somsen R.J., Jennings J.R., Van der Molen M.W. (Nov 2004). The cardiac cycle time effect revisited...Temporal dynamics of the central-vagal modulation of heart rate in human reaction time tasks. Psychophysiology. 41(6), pp. 941-953. Van der Molen , M

  16. KENNEDY SPACE CENTER, FLA. - NASA leaders discuss the Agency’s One NASA initiative with selected employees at the KSC Visitor Complex IMAX Theater®. From left are KSC Director Jim Kennedy; James Jennings, NASA’s associate deputy administrator for institutions and asset management; Ed Weiler, associate administrator for Space Science; Kevin Peterson, Dryden Flight Research Center director; incoming KSC Deputy Director Woodrow Whitlow; and implementation team lead Johnny Stevenson. Glenn Research Center Director Dr. Julian Earls gave a motivational speech during the luncheon held at the Visitor Complex Debus Conference Center.

    NASA Image and Video Library

    2003-08-20

    KENNEDY SPACE CENTER, FLA. - NASA leaders discuss the Agency’s One NASA initiative with selected employees at the KSC Visitor Complex IMAX Theater®. From left are KSC Director Jim Kennedy; James Jennings, NASA’s associate deputy administrator for institutions and asset management; Ed Weiler, associate administrator for Space Science; Kevin Peterson, Dryden Flight Research Center director; incoming KSC Deputy Director Woodrow Whitlow; and implementation team lead Johnny Stevenson. Glenn Research Center Director Dr. Julian Earls gave a motivational speech during the luncheon held at the Visitor Complex Debus Conference Center.

  17. From the Orbital Implementation of the Kinetic Theory to the Polarization Propagator Method in the Study of Energy Deposition Problems

    NASA Astrophysics Data System (ADS)

    Cabrera-Trujillo, R.; Cruz, S. A.; Soullard, J.

    The energy deposited by swift atomic-ion projectiles when colliding with a given target material has been a topic of special scientific interest for the last century due to the variety of applications of ion beams in modern materials technology as well as in medical physics. In this work, we summarize our contributions in this field as a consequence of fruitful discussions and enlightening ideas put forward by one of the main protagonists in stopping power theory during the last three decades: Jens Oddershede. Our review, mainly motivated by Jens' work, evolves from the extension of the orbital implementation of the kinetic theory of stopping through the orbital local plasma approximation, its use in studies of orbital and total mean excitation energies for the study of atomic and molecular stopping until the advances on generalized oscillator strength and sum rules in the study of stopping cross sections. Finally, as a tribute to Jens' work on the orbital implementation of the kinetic theory of stopping, in this work we present new results on the use of the Thomas-Fermi-Dirac-Weizsäcker density functional for the calculation of orbital and total atomic mean excitation energies. The results are applied to free-atoms and and extension is done to confined atoms - taking Si as an example - whereby target pressure effects on stopping are derived. Hence, evidence of the far-yield of Jens' ideas is given.

  18. Black pepper powder microbiological quality improvement using DBD systems in atmospheric pressure

    NASA Astrophysics Data System (ADS)

    Grabowski, Maciej; Hołub, Marcin; Balcerak, Michał; Kalisiak, Stanisław; Dąbrowski, Waldemar

    2015-07-01

    Preliminary results are given regarding black pepper powder decontamination using dielectric barrier discharge (DBD) plasma in atmospheric pressure. Three different DBD reactor constructions were investigated, both packaged and unpackaged material was treated. Due to potential, industrial applications, in addition to microbiological results, water activity, loss of mass and the properties of packaging material, regarding barrier properties were investigated. Argon based treatment of packed pepper with DBD reactor configuration is proposed and satisfactory results are presented for treatment time of 5 min or less. Contribution to the topical issue "The 14th International Symposium on High Pressure Low Temperature Plasma Chemistry (HAKONE XIV)", edited by Nicolas Gherardi, Ronny Brandenburg and Lars Stollenwark

  19. KSC-03pd1114

    NASA Image and Video Library

    2003-04-09

    KENNEDY SPACE CENTER, FLA. -- Space Gateway Support Security Officer Jeff Ellison signs in a worker at the Nacogdoches site. In the background, NASA site lead Ronnie Lawson (left) speaks with his United Space Alliance counterpart George Odom. Kennedy Space Center workers are participating in the Columbia Recovery efforts at the Lufkin (Texas) Command Center, four field sites in East Texas, and the Barksdale, La., hangar site. KSC is working with representatives from other NASA Centers and with those from a number of federal, state and local agencies in the recovery effort. KSC provides vehicle technical expertise in the field to identify, collect and return Shuttle hardware to KSC.

  20. Governor Bush makes first phone call to KSC using new area code

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the videoconference room at Headquarters, key representatives of KSC contractors, along with KSC directorates, fill the room during an early morning phone call from Florida Governor Jeb Bush (seen on the video screen) in Tallahassee, Fla. The call is to inaugurate the change of KSC's area code from 407 to 321, effective today. Deputy Director for Business Operations Jim Jennings (fourth from right) received the call. Next to Jennings (at his right) is seated Robert Osband, Florida Space Institute, who suggested the 3-2-1 sequence to reflect the importance of the space industry to Florida's space coast.

  1. KSC-04pd2017

    NASA Image and Video Library

    2004-09-21

    KENNEDY SPACE CENTER, FLA. - Jim Jennings, deputy associate administrator for Institutions and Asset Management at NASA Headquarters, signs an autograph for a student at Gainesville Elementary School, a NASA Explorer School in Gainesville, Ga. Jennings visited to the school to share the new vision for space exploration with the next generation of explorers. Accompanying him was KSC Deputy Director Dr. Woodrow Whitlow Jr., who talked with students about our destiny as explorers, NASA’s stepping stone approach to exploring Earth, the Moon, Mars and beyond, how space impacts our lives, and how people and machines rely on each other in space.

  2. Cigarette quitlines, taxes, and other tobacco control policies: a state-level analysis.

    PubMed

    Brown, Henry Shelton; Karson, Steve

    2013-06-01

    This paper estimates monthly quitline calls using panel data at the state level from January 2005 to June 2010. Calls to state quitline numbers (or 1-800-QUITNOW) were measured per million adult smokers in each state. The policies considered include excise taxes, workplace and public smoking bans, and a Peter Jennings television-based program warning of the health risks of smoking. We found that people anticipating increases in prices begin attempting to quit by calling quitlines. Finally, the Peter Jennings media campaign was highly correlated with quitline calls. Copyright © 2012 John Wiley & Sons, Ltd.

  3. KSC-2010-4576

    NASA Image and Video Library

    2010-09-05

    ORLANDO, Fla. -- During the 2010 Tom Joyner Family Reunion, Jim Jennings talks to attendees at the Gaylord Palms Convention Center in Orlando, Fla. To encourage student attendees to focus on pursuing careers in science, technology, engineering and mathematics (STEM), NASA featured some of its greatest legends and trailblazers during a panel discussion at the reunion event. Other panel members included NASA astronaut Leland Melvin, Christine Darden, Lew Braxton, Robyn Gordon, Jim Jennings, and space activist and actress Nichelle Nichols. NASA's Education Office sponsored the panel discussion and educational activities as part of the agency's "Summer of Innovation" initiative and the federal "Educate to Innovate" campaign. Photo credit: NASA/Amanda Diller

  4. KSC-04pd2005

    NASA Image and Video Library

    2004-09-21

    KENNEDY SPACE CENTER, FLA. - Jim Jennings, deputy associate administrator for Institutions and Asset Management at NASA Headquarters, talks to students at Gainesville Elementary School, a NASA Explorer School in Gainesville, Ga. Jennings visited the school to share the new vision for space exploration with the next generation of explorers. Also visiting the school was astronaut Leland Melvin and KSC Deputy Director Dr. Woodrow Whitlow Jr., seated at right. Whitlow talked with students about our destiny as explorers, NASA’s stepping stone approach to exploring Earth, the Moon, Mars and beyond, how space impacts our lives, and how people and machines rely on each other in space.

  5. KSC-04pd2000

    NASA Image and Video Library

    2004-09-21

    KENNEDY SPACE CENTER, FLA. - KSC Deputy Director Dr. Woodrow Whitlow Jr. (left) talks with staff members of Gainesville Elementary School, a NASA Explorer School in Gainesville, Ga. In the background are Bruce Buckingham (left) , NASA KSC News Chief, and Jim Jennings, deputy associate administrator for Institutions and Asset Management at NASA Headquarters. Jennings shared the new vision for space exploration with this next generation of explorers. Whitlow talked with students about our destiny as explorers, NASA’s stepping stone approach to exploring Earth, the Moon, Mars and beyond, how space impacts our lives, and how people and machines rely on each other in space.

  6. KENNEDY SPACE CENTER, FLA. - NASA and government officials are gathered to hear about the assets of the Central Florida Research Park, near Orlando, as the site of NASA’s new Shared Services Center. Seated at right are Lisa Malone, director of KSC External Affairs, and Joel Wells, with the Government Relations Office. Fourth from right is Jim Jennings, NASA deputy associate administrator for institutions and asset management. Six sites around the U.S. are under consideration for the center, which would centralize NASA’s payroll, accounting, human resources, facilities and procurement offices that are now handled at each field center. The consolidation is part of the One NASA focus.

    NASA Image and Video Library

    2004-02-19

    KENNEDY SPACE CENTER, FLA. - NASA and government officials are gathered to hear about the assets of the Central Florida Research Park, near Orlando, as the site of NASA’s new Shared Services Center. Seated at right are Lisa Malone, director of KSC External Affairs, and Joel Wells, with the Government Relations Office. Fourth from right is Jim Jennings, NASA deputy associate administrator for institutions and asset management. Six sites around the U.S. are under consideration for the center, which would centralize NASA’s payroll, accounting, human resources, facilities and procurement offices that are now handled at each field center. The consolidation is part of the One NASA focus.

  7. KENNEDY SPACE CENTER, FLA. - KSC Director Jim Kennedy (left) and incoming KSC Deputy Director Woodrow Whitlow talk about One NASA during the rollout of the Agency initiative at KSC. They were joined at the IMAX Theater® by other NASA leaders James Jennings, NASA’s associate deputy administrator for institutions and asset management; Ed Weiler, associate administrator for Space Science; Kevin Peterson, Dryden Flight Research Center director; and implementation team lead Johnny Stevenson to explain how their respective centers contribute to One NASA. Glenn Research Center Director Dr. Julian Earls gave a motivational speech during the luncheon held at the Visitor Complex Debus Conference Center.

    NASA Image and Video Library

    2003-08-20

    KENNEDY SPACE CENTER, FLA. - KSC Director Jim Kennedy (left) and incoming KSC Deputy Director Woodrow Whitlow talk about One NASA during the rollout of the Agency initiative at KSC. They were joined at the IMAX Theater® by other NASA leaders James Jennings, NASA’s associate deputy administrator for institutions and asset management; Ed Weiler, associate administrator for Space Science; Kevin Peterson, Dryden Flight Research Center director; and implementation team lead Johnny Stevenson to explain how their respective centers contribute to One NASA. Glenn Research Center Director Dr. Julian Earls gave a motivational speech during the luncheon held at the Visitor Complex Debus Conference Center.

  8. KENNEDY SPACE CENTER, FLA. - NASA’s Ed Weiler, associate administrator for Space Science, speaks to employees and guests during the rollout at KSC of the Agency initiative One NASA . The event was held at the IMAX Theater®. Explaining how their respective centers contribute to One NASA, along with Weiler, were KSC Director Jim Kennedy; James Jennings, NASA’s associate deputy administrator for institutions and asset management; Kevin Peterson, Dryden Flight Research Center director; incoming KSC Deputy Director Woodrow Whitlow; and implementation team lead Johnny Stevenson. Glenn Research Center Director Dr. Julian Earls gave a motivational speech during the luncheon held at the Visitor Complex Debus Conference Center.

    NASA Image and Video Library

    2003-08-20

    KENNEDY SPACE CENTER, FLA. - NASA’s Ed Weiler, associate administrator for Space Science, speaks to employees and guests during the rollout at KSC of the Agency initiative One NASA . The event was held at the IMAX Theater®. Explaining how their respective centers contribute to One NASA, along with Weiler, were KSC Director Jim Kennedy; James Jennings, NASA’s associate deputy administrator for institutions and asset management; Kevin Peterson, Dryden Flight Research Center director; incoming KSC Deputy Director Woodrow Whitlow; and implementation team lead Johnny Stevenson. Glenn Research Center Director Dr. Julian Earls gave a motivational speech during the luncheon held at the Visitor Complex Debus Conference Center.

  9. Distribution and contamination status of chromium in surface sediments of northern Kaohsiung Harbor, Taiwan.

    PubMed

    Dong, Cheng-Di; Chen, Chiu-Wen; Chen, Chih-Feng

    2013-07-01

    The distribution, enrichment, accumulation, and potential ecological risk of chromium (Cr) in the surface sediments of northern Kaohsiung Harbor, Taiwan, China were investigated. Sediment samples from ten locations located between the river mouths and harbor entrance of northern Kaohsiung Harbor were collected quarterly in 2011 and characterized for Cr, aluminum, water content, organic matter, total nitrogen, total phosphorous, total grease, and grain size. Results showed that the Cr concentrations varied from 27.0 to 361.9 mg/kg with an average of (113.5 +/- 87.0) mg/kg. High Cr concentration was observed near the Jen-Gen River mouth. The mean Cr concentration was high at 255.5 mg/kg, which was at least 2 to 7 times than that of other sites. This might imply significant Cr contribution from upstream receiving tanneries wastewater into the Jen-Gen River. The spatial distribution of Cr reveals relatively high in the river mouth region, especially in Jen-Gen River, and gradually diminishes toward the harbor entrance region. This indicates that the major sources of Cr pollution from upstream industrial and municipal wastewaters discharged along the river bank; and Cr may drift with sea current and be dispersed into open sea. Moreover, Cr concentrations correlated closely to the physical-chemical properties of the sediments, which suggested the influence of industrial and municipal wastewaters discharged from the neighboring industrial parks and river basins. Results from the enrichment factor and geo-accumulation index analyses imply that the Jen-Gen River sediments can be characterized as moderate enrichment and none to medium accumulation of Cr, respectively. However, results of potential ecological risk index indicate that the sediment has low ecological potential risk. The results can provide valuable information to developing future strategies for the management of river mouth and harbor.

  10. Governor Bush makes first phone call to KSC using new area code

    NASA Technical Reports Server (NTRS)

    1999-01-01

    At 8 a.m. in the videoconference room at Headquarters, Deputy Director for Business Operations Jim Jennings (center) makes the connection for a phone call from Florida Governor Jeb Bush and Center Director Roy Bridges in Tallahassee, Fla. The call is to inaugurate the change of KSC's area code from 407 to 321, effective today. Key representatives of KSC contractors, along with KSC directorates, fill the room where the phone call is being received. Seated next to Jennings are Robert Osband (left), Florida Space Institute, and Col. Stephan Duresky (right), vice commander, 45th Space Wing. Osband is the one who suggested the 3-2-1 sequence to reflect the importance of the space industry to Florida's space coast.

  11. Governor Bush makes first phone call to KSC using new area code

    NASA Technical Reports Server (NTRS)

    1999-01-01

    At 8 a.m. in the videoconference room at Headquarters, Deputy Director for Business Operations Jim Jennings (center) waits for a phone call from Florida Governor Jeb Bush and Center Director Roy Bridges in Tallahassee, Fla. The call is to inaugurate the change of KSC's area code from 407 to 321, effective today. Key representatives of KSC contractors, along with KSC directorates, fill the room where the phone call is being received. Seated next to Jennings are Robert Osband (left), Florida Space Institute, and Col. Stephan Duresky (right), vice commander, 45th Space Wing. Osband is the one who suggested the 3-2-1 sequence, to reflect the importance of the space industry to Florida's space coast.

  12. 78 FR 9724 - Endangered and Threatened Wildlife and Plants; Receipt of Application for Incidental Take Permit...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-11

    ...: Dawn Jennings, Acting Field Supervisor, Jacksonville Ecological Services Field Office, Attn: Permit... their habitats, and (2) minor or negligible effects on other environmental values or resources. Next...

  13. Ronnie, Millie, Lila--Women's History for Games: A Manifesto and a Way Forward

    ERIC Educational Resources Information Center

    Kocurek, Carly

    2017-01-01

    The author discusses how, in practice, historians often obscure the effect of women's lives, work, and contributions on their topic, and she takes special note of video game history. Using both history and film studies as examples, she argues that games historians can and should adopt feminist viewpoints to help ensure a fuller, more diverse…

  14. 78 FR 20689 - Endangered and Threatened Wildlife and Plants; Receipt of Application for Renewal of Incidental...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-05

    ... Jennings, Acting Field Supervisor, Jacksonville Ecological Services Field Office, Attn: Permit number... effects on other environmental values or resources. Next Steps We will evaluate the HCP and comments we...

  15. KSC-04PD-2008

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. Astronaut Leland Melvin talks and interacts with students at Gainesville Elementary School, a NASA Explorer School in Gainesville, Ga. Melvin joined Jim Jennings, deputy associate administrator for Institutions and Asset Management at NASA Headquarters, on the visit to the school to share the new vision for space exploration with the next generation of explorers. Also accompanying Jennings was KSC Deputy Director Dr. Woodrow Whitlow Jr., who talked with students about our destiny as explorers, NASAs stepping stone approach to exploring Earth, the Moon, Mars and beyond, how space impacts our lives, and how people and machines rely on each other in space. Melvin talked about the importance of teamwork and what it takes for mission success.

  16. KSC-04PD-2011

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. Almost hidden in the center amid the sea of students at Gainesville Elementary School, a NASA Explorer School in Gainesville, Ga., are Jim Jennings, deputy associate administrator for Institutions and Asset Management at NASA Headquarters; Dr. Woodrow Whitlow Jr., KSC deputy director; and astronaut Leland Melvin. Whitlow and Melvin accompanied Jennings on the visit to the school to share the new vision for space exploration with the next generation of explorers. Whitlow talked about our destiny as explorers, NASAs stepping stone approach to exploring Earth, the Moon, Mars and beyond, how space impacts our lives, and how people and machines rely on each other in space. Melvin talked about the importance of teamwork and what it takes for mission success.

  17. KSC-04PD-2007

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. Astronaut Leland Melvin talks and interacts with students at Gainesville Elementary School, a NASA Explorer School in Gainesville, Ga. Melvin joined Jim Jennings, deputy associate administrator for Institutions and Asset Management at NASA Headquarters, on the visit to the school to share the new vision for space exploration with the next generation of explorers. Also accompanying Jennings was KSC Deputy Director Dr. Woodrow Whitlow Jr., who talked with students about our destiny as explorers, NASAs stepping stone approach to exploring Earth, the Moon, Mars and beyond, how space impacts our lives, and how people and machines rely on each other in space. Melvin talked about the importance of teamwork and what it takes for mission success.

  18. 7 CFR 301.50-3 - Quarantined areas.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    .... Jennings County. The entire county. Johnson County. The entire county. Kosciusko County. The entire county.... Pennsylvania The entire State. Rhode Island The entire State Vermont The entire State. Virginia Clarke County...

  19. 7 CFR 301.50-3 - Quarantined areas.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    .... Jennings County. The entire county. Johnson County. The entire county. Kosciusko County. The entire county.... Pennsylvania The entire State. Rhode Island The entire State Vermont The entire State. Virginia Clarke County...

  20. 7 CFR 301.50-3 - Quarantined areas.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    .... Jennings County. The entire county. Johnson County. The entire county. Kosciusko County. The entire county.... Pennsylvania The entire State. Rhode Island The entire State Vermont The entire State. Virginia Clarke County...

  1. 7 CFR 301.50-3 - Quarantined areas.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    .... Jennings County. The entire county. Johnson County. The entire county. Kosciusko County. The entire county.... Pennsylvania The entire State. Rhode Island The entire State Vermont The entire State. Virginia Clarke County...

  2. 7 CFR 301.50-3 - Quarantined areas.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    .... Jennings County. The entire county. Johnson County. The entire county. Kosciusko County. The entire county.... Pennsylvania The entire State. Rhode Island The entire State Vermont The entire State. Virginia Clarke County...

  3. Patient safety initiatives from around the world.

    PubMed

    Tingle, John

    2017-05-25

    John Tingle, Reader in Health Law at Nottingham Trent University, and Jen Minford, Junior Doctor Co-ordinator, Nottingham University Hospitals NHS Trust, discuss initiatives presented at a global summit on patient safety.

  4. 78 FR 61352 - Change in Bank Control Notices; Acquisitions of Shares of a Bank or Bank Holding Company

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-03

    ... shares of FirstSecure Bank and Trust Company, Palos Hill, IL. B. Federal Reserve Bank of Minneapolis..., Julie Jennings, Lone Tree, Colorado, and R. Will Isham, Gordon, Nebraska, in their individual capacities...

  5. 10. Historic American Buildings Survey CFA Staff, Photographer, 1972 FIRST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. Historic American Buildings Survey CFA Staff, Photographer, 1972 FIRST- SECOND- FLOOR PLAN J. L. S. Jennings, Jr., Delineator - Edward H. Everett House, 1606 Twenty-third Street Northwest, Washington, District of Columbia, DC

  6. KENNEDY SPACE CENTER, FLA. - KSC Director Jim Kennedy and Glenn Research Center Director Dr. Julian Earls share the stage during the rollout of the One NASA initiative at KSC. Earls gave a motivational speech during the luncheon held at the Visitor Complex Debus Conference Center. The event was held at the IMAX Theater® where NASA leaders discussed One NASA with selected employees. Explaining how their respective centers contribute to One NASA, along with Kennedy and Earls, were James Jennings, NASA’s associate deputy administrator for institutions and asset management; Ed Weiler, associate administrator for Space Science; Kevin Peterson, Dryden Flight Research Center director; incoming KSC Deputy Director Woodrow Whitlow; and implementation team lead Johnny Stevenson.

    NASA Image and Video Library

    2003-08-20

    KENNEDY SPACE CENTER, FLA. - KSC Director Jim Kennedy and Glenn Research Center Director Dr. Julian Earls share the stage during the rollout of the One NASA initiative at KSC. Earls gave a motivational speech during the luncheon held at the Visitor Complex Debus Conference Center. The event was held at the IMAX Theater® where NASA leaders discussed One NASA with selected employees. Explaining how their respective centers contribute to One NASA, along with Kennedy and Earls, were James Jennings, NASA’s associate deputy administrator for institutions and asset management; Ed Weiler, associate administrator for Space Science; Kevin Peterson, Dryden Flight Research Center director; incoming KSC Deputy Director Woodrow Whitlow; and implementation team lead Johnny Stevenson.

  7. KENNEDY SPACE CENTER, FLA. - Dryden Flight Research Center Director Kevin Peterson talks about One NASA during the rollout of the Agency initiative at KSC. The event was held at the IMAX Theater® where NASA leaders discussed One NASA with selected employees. Explaining how their respective centers contribute to One NASA, along with Peterson, were KSC Director Jim Kennedy, James Jennings, NASA’s associate deputy administrator for institutions and asset management; Ed Weiler, associate administrator for Space Science; Kevin Peterson, Dryden Flight Research Center director; incoming KSC Deputy Director Woodrow Whitlow; and implementation team lead Johnny Stevenson. Glenn Research Center Director Dr. Julian Earls gave a motivational speech during the luncheon held at the Visitor Complex Debus Conference Center.

    NASA Image and Video Library

    2003-08-20

    KENNEDY SPACE CENTER, FLA. - Dryden Flight Research Center Director Kevin Peterson talks about One NASA during the rollout of the Agency initiative at KSC. The event was held at the IMAX Theater® where NASA leaders discussed One NASA with selected employees. Explaining how their respective centers contribute to One NASA, along with Peterson, were KSC Director Jim Kennedy, James Jennings, NASA’s associate deputy administrator for institutions and asset management; Ed Weiler, associate administrator for Space Science; Kevin Peterson, Dryden Flight Research Center director; incoming KSC Deputy Director Woodrow Whitlow; and implementation team lead Johnny Stevenson. Glenn Research Center Director Dr. Julian Earls gave a motivational speech during the luncheon held at the Visitor Complex Debus Conference Center.

  8. KENNEDY SPACE CENTER, FLA. - KSC’s incoming Deputy Director Woodrow Whitlow speaks to employees and guests during the rollout at KSC of the Agency initiative One NASA . The event was held at the IMAX Theater® where NASA leaders discussed One NASA with selected employees. Explaining how their respective centers contribute to One NASA, along with Whitlow, were KSC Director Jim Kennedy; James Jennings, NASA’s associate deputy administrator for institutions and asset management; Ed Weiler, associate administrator for Space Science; Kevin Peterson, Dryden Flight Research Center director; and implementation team lead Johnny Stevenson. Glenn Research Center Director Dr. Julian Earls gave a motivational speech during the luncheon held at the Visitor Complex Debus Conference Center.

    NASA Image and Video Library

    2003-08-20

    KENNEDY SPACE CENTER, FLA. - KSC’s incoming Deputy Director Woodrow Whitlow speaks to employees and guests during the rollout at KSC of the Agency initiative One NASA . The event was held at the IMAX Theater® where NASA leaders discussed One NASA with selected employees. Explaining how their respective centers contribute to One NASA, along with Whitlow, were KSC Director Jim Kennedy; James Jennings, NASA’s associate deputy administrator for institutions and asset management; Ed Weiler, associate administrator for Space Science; Kevin Peterson, Dryden Flight Research Center director; and implementation team lead Johnny Stevenson. Glenn Research Center Director Dr. Julian Earls gave a motivational speech during the luncheon held at the Visitor Complex Debus Conference Center.

  9. Human Robotic Study at Houghton Crater - virtual reality study from NASA Ames (FFC) Future Fight

    NASA Technical Reports Server (NTRS)

    2002-01-01

    Human Robotic Study at Houghton Crater - virtual reality study from NASA Ames (FFC) Future Fight Central simulator tower L-R: Dr Geoffrey Briggs; Jen Jasper (seated); Dr Jan Akins and Mr. Tony Gross, Ames

  10. Detail of Bright Angel stone vault, containing condenser, Hoffman condensation ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail of Bright Angel stone vault, containing condenser, Hoffman condensation pump, Jennings vacuum heating pump, and misc. pipes and valves. - Grand Canyon Village Utilities, Grand Canyon National Park, Grand Canyon Village, Coconino County, AZ

  11. 11. Historic American Buildings Survey Photocopy Commission of Fine Arts ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. Historic American Buildings Survey Photocopy Commission of Fine Arts Staff, 1972 FIRST-FLOOR PLAN J. L. S. Jennings, Jr., Delineator, Aug. 1972 - Walsh-Mclean House, 2020 Massachusetts Avenue Northwest, Washington, District of Columbia, DC

  12. Asthma in Children: MedlinePlus Health Topic

    MedlinePlus

    ... and Research) Treating Asthma with Inhaled Steroids (Consumers Union of U.S.) - PDF What If My Child Doesn' ... Study Helps Jeff Long Battle Illness Outrunning Asthma: Football Player Rashad Jennings Battled Childhood Asthma with Exercise ...

  13. Wheelchairs

    MedlinePlus

    ... Others have disabilities due to muscular dystrophy or cerebral palsy . In some cases, kids have wheelchairs but don' ... Therapist In the Band: Jens' Story Spina Bifida Cerebral Palsy View more About Us Contact Us Partners Editorial ...

  14. Steep cut slope composting : field trials and evaluation : project summary report.

    DOT National Transportation Integrated Search

    2011-04-01

    This project is a continuation of earlier work performed by Montana State University (Jennings et al. 2007) evaluating compost application on, and incorporation into, soils on steep cut slopes for the Montana Department of Transportation (MDT). The e...

  15. BASF confirms plans for world-scale cracker on the Gulf Coast

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wood, A.

    BASF Corp. has confirmed plans that it will build a world-scale cracker on the Gulf Coast. The company has completed preliminary work, and {open_quotes}the results of our project analysis have been extremely encouraging,{close_quotes} says chemicals president Carl A. Jennings. {open_quotes}We`ll proceed with high priority to have the cracker ready for startup in second-half 2000.{close_quotes} The company says it will select a location for the project by mid-1977. In addition to considering its sites at Geismar, LA; Freeport, TX; and Altamira, Mexico, BASF says that {open_quotes}cooperative arrangements{close_quotes} are being looked at. That could include locating the project at a different site,more » adjacent to a feedstock source, according to Jennings. He says the project could also include joint venture partners.« less

  16. Bridenstine Sworn In As NASA Administrator

    NASA Image and Video Library

    2018-04-23

    NASA Associate Administrator for the Office of Communications Jen Rae Wang introduces Jim Bridenstine prior to his swearing-in as the 13th NASA Administrator, Monday, April 23, 2018 at NASA Headquarters in Washington. Photo Credit: (NASA/Joel Kowsky)

  17. Can teaching hospitals use serial formative OSCEs to improve student performance?

    PubMed

    Lien, Heng-Hui; Hsu, Sang-Feng; Chen, Shu-Chen; Yeh, Jiann-Horng

    2016-10-14

    We report on interns' clinical competence and experiences of an objective structured clinical examination (OSCE) training program over 3 years. We aimed to determine whether repeated formative OSCEs allow teaching hospitals to improve the effectiveness of clinical training and help interns to achieve high scores in the national summative OSCE. This study included 207 participants, among whom 82 were interns who had completed four mock OSCEs and a national OSCE at the clinical center of Cathay General Hospital (CGH). The other 125 participants were final-year medical students from Fu-Jen University who had completed the national OSCE between 2013 and 2015 at one of four teaching hospitals (including CGH). CGH interns were categorized into three groups according to the medical school attended and Fu-Jen University students were grouped according to their training hospitals. CGH held four mock OSCEs (30 stations), whereas each of the four training hospitals for Fu-Jen students each held one or two OSCEs (6-12 stations) annually. Differences in the mean OSCE scores among groups were analyzed. The medical school attended, pre-internship OSCE experience and the frequency of mock OSCEs held by training hospitals were independent factors in this study. The cumulative mean scores for five OSCEs among three groups of students trained at CGH tended to increase from the first OSCE (OSCE1) to the fifth (OSCE5). The mean score of the students who attended Fu-Jen Medical School was higher than that of students who graduated from foreign medical schools in all five OSCEs; however, the differences were significant only for OSCE2 (P = 0.022) and OSCE3 (P = 0.027). The mean national OSCE scores of FJU students showed no statistically significant differences among the four training hospitals for 2013; however, students training at CGH had significantly higher mean scores in the 2014 (P = 0.001) and 2015 (P = 0.005) OSCEs compared with students training at the other three

  18. Moisture Monitoring at Area G, Technical Area 54, Los Alamos National Laboratory, 2016 Status Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Levitt, Daniel Glenn; Birdsell, Kay Hanson; Jennings, Terry L.

    Hydrological characterization and moisture monitoring activities provide data required for evaluating the transport of subsurface contaminants in the unsaturated and saturated zones beneath Area G, and for the Area G Performance Assessment and Composite Analysis. These activities have been ongoing at Area G, Technical Area 54 of the Los Alamos National Laboratory since waste disposal operations began in 1957. This report summarizes the hydrological characterization and moisture monitoring activities conducted at Area G. It includes moisture monitoring data collected from 1986 through 2016 from numerous boreholes and access tubes with neutron moisture meters, as well as data collected by automatedmore » dataloggers for water content measurement sensors installed in a waste disposal pit cover, and buried beneath the floor of a waste disposal pit. This report is an update of a nearly identical report by Levitt et al., (2015) that summarized data collected through early 2015; this report includes additional moisture monitoring data collected at Pit 31 and the Pit 38 extension through December, 2016. It also includes information from the Jennings and French (2009) moisture monitoring report and includes all data from Jennings and French (2009) and the Draft 2010 Addendum moisture monitoring report (Jennings and French, 2010). For the 2015 version of this report, all neutron logging data, including neutron probe calibrations, were investigated for quality and pedigree. Some data were recalculated using more defensible calibration data. Therefore, some water content profiles are different from those in the Jennings and French (2009) report. All of that information is repeated in this report for completeness. Monitoring and characterization data generally indicate that some areas of the Area G vadose zone are consistent with undisturbed conditions, with water contents of less than five percent by volume in the top two layers of the Bandelier tuff at Area G. These data

  19. Diamond in 3-D

    NASA Image and Video Library

    2004-08-20

    This 3-D, microscopic imager mosaic of a target area on a rock called Diamond Jenness was taken after NASA Mars Exploration Rover Opportunity ground into the surface with its rock abrasion tool for a second time. 3D glasses are necessary.

  20. LOCATION OF ACYL GROUPS ON TWO PARTLY ACYLATED GLYCOLIPIDS FROM STRAINS OF USTILAGO (SMUT FUNGI),

    DTIC Science & Technology

    erythritol from Ustilago sp. (probably U. nuda (Jens.) Rostr. = U. tritici (Pers.) Rostr.) PRL-627 were acetalated with methyl vinyl ether, deacylated...Partly acylated ustilagic acids 8 (from Ustilago maydis (DC) Corda (= U. zeae Unger) PRL-119), consisting of partially esterified beta-cellobiosyl

  1. Resistance in School and Society: Public and Pedagogical Debates about Eugenics, 1900-1947.

    ERIC Educational Resources Information Center

    Selden, Steven

    1988-01-01

    This article reviews positions of scientists, educators and publicists who resisted eugenics and determinism. The nature nurture controversy is discussed, as well as the impact of eugenics on American classrooms. Specific attention is given to four resisters: Dewey, Bagley, Jennings, and Lippmann. (IAH)

  2. KENNEDY SPACE CENTER, FLA. - At the rollout of the One NASA initiative at KSC, Glenn Research Center Director Dr. Julian Earls embraces implementation team lead Johnny Stevenson while KSC Director Jim Kennedy (left) applauds. Earls gave a motivational speech during the luncheon held at the Visitor Complex Debus Conference Center. The event was held at the IMAX Theater® where NASA leaders discussed One NASA with selected employees. Explaining how their respective centers contribute to One NASA, along with Kennedy and Earls, were James Jennings, NASA’s associate deputy administrator for institutions and asset management; Ed Weiler, associate administrator for Space Science; Kevin Peterson, Dryden Flight Research Center director; incoming KSC Deputy Director Woodrow Whitlow; and implementation team lead Johnny Stevenson.

    NASA Image and Video Library

    2003-08-20

    KENNEDY SPACE CENTER, FLA. - At the rollout of the One NASA initiative at KSC, Glenn Research Center Director Dr. Julian Earls embraces implementation team lead Johnny Stevenson while KSC Director Jim Kennedy (left) applauds. Earls gave a motivational speech during the luncheon held at the Visitor Complex Debus Conference Center. The event was held at the IMAX Theater® where NASA leaders discussed One NASA with selected employees. Explaining how their respective centers contribute to One NASA, along with Kennedy and Earls, were James Jennings, NASA’s associate deputy administrator for institutions and asset management; Ed Weiler, associate administrator for Space Science; Kevin Peterson, Dryden Flight Research Center director; incoming KSC Deputy Director Woodrow Whitlow; and implementation team lead Johnny Stevenson.

  3. Delta Pi Epsilon National Conference Book of Readings (1999).

    ERIC Educational Resources Information Center

    Delta Pi Epsilon Society, Little Rock, AR.

    This publication contains 22 refereed research papers, 4 refereed action research and classroom application papers, and 3 research training papers from a national conference on promoting excellence in research and teaching for business. The research papers are "Analysis of Executives' Written Documents" (Jennings, Vice); "Assessment…

  4. Bridenstine Sworn In As NASA Administrator

    NASA Image and Video Library

    2018-04-23

    NASA Associate Administrator for the Office of Communications Jen Rae Wang introduces Jim Bridenstine and Vice President Mike Pence ahead of Bridenstine being sworn in as the 13th NASA Administrator, Monday, April 23, 2018 at NASA Headquarters in Washington. Photo Credit: (NASA/Bill Ingalls)

  5. Projected Costs of U.S. Nuclear Forces, 2014 to 2023

    DTIC Science & Technology

    2013-12-01

    uranium and pluto- nium, and also includes several large construction projects for new facilities to support that mission); $12 billion is for...contributed to the analysis with guidance from Sarah Jennings. Justin Falk of CBO provided helpful comments on the report, as did Russell Rumbaugh

  6. Growth in DoD’s Budget From 2000 to 2014

    DTIC Science & Technology

    2014-11-01

    Julie Topoleski and Michael Simpson contributed to the analysis. Christina Hawley Anthony, Kent Christensen, Sarah Jennings, David Newman...and Maureen Costantino prepared it for publication. An electronic version is available on CBO’s website (www.cbo.gov/publication/ 49764). Douglas W . Elmendorf DirectorCBO

  7. Outcomes in pediatric neurology: a review of conceptual issues and recommendationsThe 2010 Ronnie Mac Keith Lecture.

    PubMed

    Ronen, Gabriel M; Fayed, Nora; Rosenbaum, Peter L

    2011-04-01

    This paper discusses how to evaluate whether, and in what ways, treatments affect the lives of children with neurological conditions and their families. We argue that professionals should incorporate perspectives from patients and families to help them make decisions about what 'outcomes' are important, and we discuss how those outcomes might be assessed. A case vignette illustrates the differences and complementarity between the perspectives of clinicians and those of children and their parents. We recommend methods for expanding the range of relevant health outcomes in child neurology to include those that reflect the ways patients and families view their conditions and our interventions. We explore the added value of a 'non-categorical' approach to the choice of outcomes. The International Classification of Functioning, Disability and Health is a useful biopsychosocial framework to 'rule in' relevant aspects of child and family issues to create a dynamic system of possible influences on outcomes. We examine the meaning of 'health', 'health-related quality of life', and 'quality of life' as related but conceptually distinct outcomes. Specific issues are discussed about the construction, validation, and appraisal of outcome measures, as well as practical recommendations on how to select outcome measures in the clinical setting and research. © The Authors. Developmental Medicine & Child Neurology © 2011 Mac Keith Press.

  8. Bridenstine Sworn In As NASA Administrator

    NASA Image and Video Library

    2018-04-23

    NASA Associate Administrator for the Office of Communications Jen Rae Wang greets Vice President Mike Pence after introducing him prior to the swearing-in of Jim Bridenstine as the 13th NASA Administrator, Monday, April 23, 2018 at NASA Headquarters in Washington. Photo Credit: (NASA/Joel Kowsky)

  9. Catalyst. Volume 11, Number 2, Spring 2010

    ERIC Educational Resources Information Center

    Ryan, Barbara E., Ed.

    2010-01-01

    "Catalyst" is a publication of the U.S. Department of Education's Higher Education Center for Alcohol and Other Drug Abuse and Violence Prevention. This issue contains the following articles: (1) Redefining Resources For Prevention; (2) Message From Kevin Jennings, OSDFS Assistant Deputy Secretary; (3) Environmental Management…

  10. 76 FR 35010 - Notice of Inventory Completion: Colorado Historical Society (History Colorado), Denver, CO

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-15

    ... remains representing a minimum of 10 individuals were removed from Pock's Garden Site (5MT.10851), in.... Jennings, the Colorado State University (CSU) Field School, investigated and transferred the individuals to... and under the direction of Mona Charles, Director of the Archaeological Field School. The site is...

  11. A Ministry of Enthusiasm: Centenary Essays on the Workers' Educational Association.

    ERIC Educational Resources Information Center

    Roberts, Stephen K., Ed.

    This collection of scholarly essays marks the centenary of the Workers' Educational Association (WEA), the largest voluntary provider of adult education in the United Kingdom. The chapters are as follows: "Introduction" (Roberts); "The WEA The Foundation and the Founder" (Jennings); "Battersea and the Formation of the…

  12. A Hundred Years Ago: Crusaders vs. Conservatives in a Furious Campaign.

    ERIC Educational Resources Information Center

    Social Education, 1996

    1996-01-01

    Investigates the issues, candidates, and political climate of the 1896 presidential election. The Democratic Party candidate, William Jennings Bryan, espoused a Populist platform attacking big business, protectionism, and the gold standard. William McKinley, the Republican Party, pro-business candidate easily won the election. Includes cartoons…

  13. Outrunning Asthma - Rashad Jennings | NIH MedlinePlus the Magazine

    MedlinePlus

    ... More MedlinePlus: Asthma National Institute of Environmental Health Sciences National Institute of Allergy and Infectious Diseases National Heart, Lung, and Blood Institute NIBIB-Supported Study NHALES Study Allergy and Asthma Foundation of America Fall 2017 Issue: Volume 12 Number ...

  14. Light curves of flat-spectrum radio sources (Jenness+, 2010)

    NASA Astrophysics Data System (ADS)

    Jenness, T.; Robson, E. I.; Stevens, J. A.

    2010-05-01

    Calibrated data for 143 flat-spectrum extragalactic radio sources are presented at a wavelength of 850um covering a 5-yr period from 2000 April. The data, obtained at the James Clerk Maxwell Telescope using the Submillimetre Common-User Bolometer Array (SCUBA) camera in pointing mode, were analysed using an automated pipeline process based on the Observatory Reduction and Acquisition Control - Data Reduction (ORAC-DR) system. This paper describes the techniques used to analyse and calibrate the data, and presents the data base of results along with a representative sample of the better-sampled light curves. A re-analysis of previously published data from 1997 to 2000 is also presented. The combined catalogue, comprising 10493 flux density measurements, provides a unique and valuable resource for studies of extragalactic radio sources. (2 data files).

  15. Research and Clinical Center for Child Development Annual Report, 1996-1997, No. 20.

    ERIC Educational Resources Information Center

    Chen, Shing-Jen, Ed.; Furutsuka, Takashi, Ed.; Shirotani, Yukari

    This annual report discusses several topics related to the work of the Clinical Center for Child Development at Hokkaido University in Sapporo, Japan. The articles are: (1) "Other's Voice/Own Voice: (Re)production of Other's Voice and Its Apprenticeship in Japanese Young Children" (Shing-Jen Chen); (2) "Intersubjectivity during…

  16. 76 FR 31884 - Reducing Regulatory Burden; Retrospective Review Under E.O. 13563

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-02

    ...: Submit comments to http://www.regulations.gov , or e-mail comments to [email protected]nasa.gov . FOR FURTHER INFORMATION CONTACT: Nanette Jennings, 202-358-0819, [email protected]nasa.gov.... NASA's plan is accessible on its Open Government Web site at http://www.nasa.gov/open/ . Submit...

  17. Presidents, Congress, and the Public Schools: The Politics of Education Reform

    ERIC Educational Resources Information Center

    Jennings, Jack

    2015-01-01

    April 2015 marks the fiftieth anniversary of the Elementary and Secondary Education Act (ESEA), the landmark legislation that has provided the foundation of federal education policy in the United States. In "Presidents, Congress, and the Public Schools," longtime policy analyst Jack Jennings examines the evolution of federal education…

  18. Examining the Relationship between Physiological Measurements and Self-Reports of Stress and Well-Being in Middle School Teachers over One School Year

    ERIC Educational Resources Information Center

    Katz, Deirdre A.; Harris, Alexis R.; Abenavoli, Rachel M.; Greenberg, Mark T.

    2013-01-01

    Educators are exposed to a variety of stressors, which can lead to poorer teaching performance, burnout, and increased student misbehavior (Jennings & Greenberg, 2009). Although self-report measures of stress are most commonly used in education research, physiological measures of stress may also contribute to the understanding of educators'…

  19. The Trial

    ERIC Educational Resources Information Center

    Bryant, Jen

    2004-01-01

    Growing up in Flemington, New Jersey, put Jen Bryant in the heart of the lore behind the Lindbergh baby kidnapping. Family stories of the events of the day and extensive research led to "The Trial," a novel in verse. The first several parts of this novel are included here.

  20. Reducing Poverty through Preschool Interventions

    ERIC Educational Resources Information Center

    Duncan, Greg J.; Ludwig, Jens; Magnuson, Katherine A.

    2007-01-01

    Greg Duncan, Jens Ludwig, and Katherine Magnuson explain how providing high-quality care to disadvantaged preschool children can help reduce poverty. In early childhood, they note, children's cognitive and socioemotional skills develop rapidly and are sensitive to "inputs" from parents, home learning environments, child care settings, and the…

  1. The Changing Politics of School Finance. Third Annual Yearbook of the American Education Finance Association.

    ERIC Educational Resources Information Center

    Cambron-McCabe, Nelda H., Ed.; Odden, Allan, Ed.

    Nine chapters focus on major areas and issues in educational finance. Chapter 1, "Turning-Point Election Periods in the Politics of Education" by Laurence Innaccone, reports on research on changes in the national political context. John F. Jennings in chapter 2, "Politics of Federal Aid," discusses social, economic, and…

  2. The Australian endemic woodwasp genus Austrocyrta Riek (Hymenoptera: Xiphydriidae)

    Treesearch

    J.T. Jennings; A.D. Austin; N.M. Schiff

    2009-01-01

    The Australian xiphydriid woodwasp genus, previously known only from a single species, A. australiensis Riek, is revised. A second distinctive species from Carnarvon National Park in southcentral Queensland, A. fasciculata Jennings & Austin, sp. nov., is described, and a key to separate the males of the two species is provided.

  3. 76 FR 43893 - Special Local Regulations; Port Huron to Mackinac Island Sail Race

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-22

    ... the vicinity of the race's starting point and to provide for the safety of the general boating public... ``Search.'' This material is also available for inspection or copying at the Docket Management Facility (M...-mail Mr. Frank Jennings, Jr., Auxiliary and Boating Safety Branch, Ninth Coast Guard District, via e...

  4. Gamer Girls, Gold Farmers, and Activism "In Real Life"

    ERIC Educational Resources Information Center

    Musgrave, Megan L.

    2016-01-01

    This essay analyzes the graphic novel "In Real Life" as an example of Cory Doctorow and Jen Wang's intention to raise young people's awareness about gender and economic disparities within the gaming industry. Broadly, "In Real Life" combats the pervasive cultural anxiety that Jane McGonigal challenges in her book "Reality…

  5. Catalyst. Volume 12, Number 1, Winter 2011

    ERIC Educational Resources Information Center

    Higher Education Center for Alcohol, Drug Abuse, and Violence Prevention, 2011

    2011-01-01

    "Catalyst" is a publication of the U.S. Department of Education's Higher Education Center for Alcohol and Drug Abuse and Violence Prevention. This issue contains the following articles: (1) What Science Tells Us About Impaired Driving Behavior And Consequences Among U.S. College Students; (2) Message From Kevin Jennings, OSDFS Assistant…

  6. Prepaying & Saving for College: Opportunities and Issues. Policy Perspectives No. 3.

    ERIC Educational Resources Information Center

    Jennings, Barbara M.; Olivas, Michael A.

    This publication provides an overview and discusses underlying issues of the college savings and prepaid tuition plans that are emerging in the states. Two papers offer different vantage points on college savings and prepaid plans in financing postsecondary education. The first paper, "The Evolution of State Plans" (Barbara M. Jennings),…

  7. 75 FR 78093 - Endangered and Threatened Wildlife and Plants; 12-Month Finding on a Petition To List the Sonoran...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-14

    ..., and Review of One Species'' (50 FR 13054, April 2, 1985); ``Review of Vertebrate Wildlife'' (50 FR... United States, and also includes the Mexican State of Sonora into the northern portion of Sinaloa. One... less of rain annually (Fritts and Jennings 1994, p. 53). One question about the distribution of the...

  8. FlyEyes: A CCD-Based Wavefront Sensor for PUEO, the CFHT Curvature AO System

    DTIC Science & Technology

    2010-09-28

    Charles Cuillandre, Kevin K.Y. Ho, Marc Baril , Tom Benedict, Jeff Ward, Jim Thomas, Derrick Salmon, Chueh-Jen Lin, Shiang-Yu Wang, Gerry Luppino...sensor for PUEO, the CFHT curvature AO system Olivier Lai, Jean-Charles Cuillandre , Kevin K.Y. Ho, lVIarc Baril , Tom Benedict, Jeff ’Varel, Jim Thomas

  9. Family Background of Beginning Education Students: Implications for Teacher Educators

    ERIC Educational Resources Information Center

    Stewart, Roger A.; Coll, Kenneth M.; Osguthorpe, Richard

    2013-01-01

    Teacher education has not historically focused on the social and emotional development of teachers even though there is evidence that such variables influence student success (Jennings & Greenberg, 2009). We believe such a focus is important and we explored variables in teacher education students' families of origin that underpin social and…

  10. A Nationwide Population-Based Approach to Study Health-Related and Psychosocial Aspects of Neurofibromatosis Type 1

    DTIC Science & Technology

    2016-07-31

    the relatively narrow focus on Wechsler’s IQ test (WAIS-IV) – a test chosen primarily due to budget constraints. Thus, to meet the requests from the...consultants allows us to re-allocate financial resources to address the limitations of our study 7 raised by the reviewers. Jens Richardt Møllegaard

  11. Are Television Commercials Still Achievement Scripts for Women?

    ERIC Educational Resources Information Center

    Yoder, Janice D.; Christopher, Jessica; Holmes, Jeffrey D.

    2008-01-01

    Content analyses of television advertising document the ubiquity of traditional images of women, yet few studies have explored their impact. One noteworthy exception is the experiment by Geis, Brown, Jennings, and Porter (1984). These researchers found that the achievement aspirations of controls and women exposed to traditional images were lower…

  12. Our People | NREL

    Science.gov Websites

    Our People Our People NRELians are scientists, research technicians, engineers, analysts, managers clerical/administrative support specialists. Meet some of our research staff below or read about them in the news. NREL researcher shown half in the laboratory and half in downtown Denver. Meet Jen

  13. The Relationship between Shared Leadership, Teacher Self-Efficacy, and Student Achievement

    ERIC Educational Resources Information Center

    Zinke, Anjanette Fuller

    2013-01-01

    Decisions about ways to improve student achievement have been of concern over the years (Reeves, 2011). Multiple reforms have been attempted (Evers, 2000; Marzano, 2000), but researchers have differed in viewpoints on their effectiveness (Jennings & Rentner, 2006; Rose, 20 I 0). State test scores in Mississippi have not risen to levels…

  14. Rhysacephala novacaledonica sp. nov. (Hymenoptera: Xiphydriidae), the first xiphydriid woodwasp from New Calendonia

    Treesearch

    John T. Jennings; Andrew D. Austin; Natham M. Schiff

    2007-01-01

    Xiphydriid woodwasps have been very rarely collected in Australasia although they are widely distributed in the region. Species have been described from the Aru, Ambon and Buru Islands, Indonesia, eastern mainland Australia, Papua New Guinea, and New Zealand. Here Rhysacephala novacaledonica Jennings & Austin, sp. nov., is described, which is the...

  15. Reflections on Urban Science Teacher-Student Self-Efficacy Dynamics

    ERIC Educational Resources Information Center

    Hagiwara, Sumi; Maulucci, Maria S. Rivera; Ramos, S. Lizette

    2011-01-01

    This forum article consists of commentaries--authored by Sumi Hagiwara, Maria S. Rivera Maulucci and Lizette Ramos--on the feature article by Virginia Jennings Bolshakova, Carla C. Johnson, and Charlene M. Czerniak. We reflect on a series of questions that take retrospective, introspective, and prospective views of self-efficacy in science…

  16. 75 FR 23608 - Final Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-04

    ... Jewett +88 Town of White Springs Street. Approximately 600 feet +109 upstream of 1st Street. Timber Lake... Hamilton Avenue, Jennings, FL 32053 Town of White Springs Maps are available for inspection at the Town Hall, 10363 Bridge Street, White Springs, FL 32096 Unincorporated Areas of Hamilton County Maps are...

  17. Mode Deactivation Therapy (MDT): A Theoretical Case Analysis on a Suicidal Adolescent

    ERIC Educational Resources Information Center

    Apsche, Jack A.; Siv, Alexander M.

    2005-01-01

    This case study presents a case study of the effectiveness of Mode deactivation therapy (MDT) (Apsche, Bass, Jennings, Murphy, Hunter, and Siv, 2005) with an adolescent male, with reactive conduct disorder, PTSD and 8 lethal suicide attempts. The youngster was hospitalized four times for suicide attempts, three previous placements in residential…

  18. Treatment Strategies for Human Arboviral Infections Applicable to Veterinary Medicine

    DTIC Science & Technology

    1992-06-16

    16. MORILL , J. C., G. B. JENNINGS, T. M. COSGRIFF, P. H. GIBBS & C. J. PETERS. 1989. Prevention of Rift Valley fever in rhesus monkeys with interferon...alpha. Rev. Infect. Dis. 2(Suppl. 4): 815. 17. MORILL , J. C., C. W. CZARNECKI & C. J. PETERS. 1991. Recombinant human interferon- gamma modulates

  19. Summary Report for the Army Research Organization (ARO) Workshop on Social Trust Computing

    DTIC Science & Technology

    2010-09-14

    5 2.5 Munindar Singh . . . . . . . . . . . . . . . . . . . . . . . . . . 5 2.6 Ugur Kuter...12 2 1 Attendees • Jen Golbeck (UMD) • Ugur Kuter (UMD) • Jim Hendler (RPI) • John O’Donnovan (UCSB...social computing applications, such as those involving personal, communal, organizational, and contractual relationships. 2.6 Ugur Kuter Every day, people

  20. Straight Talk

    ERIC Educational Resources Information Center

    Stainburn, Samantha

    2005-01-01

    Recognizing gay students remains an emotional, politically charged issue. But Kevin Jennings, the 42-year-old executive director of the Gay, Lesbian, and Straight Education Network (GLSEN), is not out to provoke shouting matches. Instead, he is quietly turning students into activists capable of changing schools on their own. Along with advocating…

  1. Fundamental Studies in the Molecular Basis of Laser Induced Retinal Damage.

    DTIC Science & Technology

    1983-09-01

    Mandel, P. (1977) Exp. Eye Res. 25, 163-169. 19. Schwabe, U., Puchstein, C. Hannemann , H. and Sochtig, E. (1979) Nature 277, 143-145. 20. Richards, J...Hagins, W. A. and Jennings , W. H. (1959) Discussion Faraday Soc. 27, 180-190. 19. Borwein, B. (1983) Anat. Rec. 205, 363-373. 20. Yoshikami, S

  2. "Culture" and the Intergenerational Transmission of Poverty: The Prevention Paradox

    ERIC Educational Resources Information Center

    Ludwig, Jens; Mayer, Susan

    2006-01-01

    Many U.S. policymakers support changing the "culture" of poor parents to encourage marriage, work, and religion as a means to end the intergenerational transmission of poverty. In this article Jens Ludwig and Susan Mayer review and evaluate research on how parental work, marriage, and religion affect children's socioeconomic status…

  3. Developing the New Infostructure

    DTIC Science & Technology

    2003-12-01

    Engineering Physics and Applied Mathematics from Cornell, and a post-doc in neurophysiology from University of Mississippi Medical School. Dr. Jens G...transport you about 6,000 miles here to England, I’ve been doing some work with, I found it, this is kind of enlightening , in England, they don’t, this

  4. National Issues in Education: The Past Is Prologue.

    ERIC Educational Resources Information Center

    Jennings, John F., Ed.

    Presenting diverse perspectives on current major education issues at the national level, this book addresses issues that have played out and will play out in the legislative process in the U.S. Congress. After the "Preface" (Jack Kosoy and Michael D. Usdan) and "Introduction" (John F. Jennings), the book is divided into four…

  5. Getting the Pipeline Flowing

    ERIC Educational Resources Information Center

    Gray, Katti

    2011-01-01

    The diagonal line in Arkansas separating academic and economic strivers from those less likely to make the grade--and then land a decent job--runs roughly from Texarkana in the southwest to Blytheville in northeast. "The wealthiest people live above that line," said Dr. James Jennings, a history professor and education department…

  6. U.S. EPA, Pesticide Product Label, D.Z.N DIAZINON 50W INSECTICIDE, 04/11/1988

    EPA Pesticide Factsheets

    2011-04-13

    ... i\\ll!Jl'i 1'; I flllt:n.lilt ;:)rl,/ 1 It). I: ;Je,:-n ,Ji 1/.1 f):)!) J~'; ,J\\'~' ;1)·;. j')r-:;ldrd (>11 <)[ ,~ J.l1';. ;\\I;,"T l'lT t '/1)" ()II :"'t l()(j '11: ()f 'vI,lt ··r. j , \\j , -10- ...

  7. Occupational exposure to ionising radiation and mortality among workers of the former Spanish Nuclear Energy Board.

    PubMed Central

    Rodríguez Artalejo, F; Castaño Lara, S; de Andrés Manzano, B; García Ferruelo, M; Iglesias Martín, L; Calero, J R

    1997-01-01

    OBJECTIVES: Firstly, to ascertain whether mortality among workers of the former Spanish Nuclear Energy Board (Junta de Energía Nuclear-JEN) was higher than that for the Spanish population overall; and secondly, if this were so, to ascertain whether this difference was associated with exposure to ionising radiation. METHODS: A retrospective follow up of a cohort of 5657 workers was carried out for the period 1954-92. Cohort mortality was compared with that for the Spanish population overall, with standardised mortality ratios (SMRs) adjusted for sex, age, and calendar period. Also, Poisson models were used to analyse mortality from lung cancer in the cohort by level of exposure to ionising radiation. RESULTS: Workers' median and mean cumulative exposures were 4.04 and 11.42 mSv, respectively. Mean annual exposure was 1.33 mSv. Excess mortality due to bone tumours was found for the cohort as a whole (six deaths observed; SMR 2.95; 95% confidence interval (95% CI) 1.08 to 6.43). Among miners, excess mortality was found for non-malignant respiratory diseases (SMR 2.94; 95% CI 2.27 to 3.75), and for lung cancer bordering on statistical significance (SMR 1.50; 95% CI 0.96 to 2.23; P = 0.055). Relative risks of dying of lung cancer from ionising radiation in the dose quartiles 2, 3, and 4 versus the lowest dose quartile, were 1.00, 1.64, and 0.94, respectively. CONCLUSIONS: Excess mortality from lung cancer was found among JEN miners. Nevertheless, no clear relation was found between mortality from lung cancer and level of exposure to ionising radiation in the JEN cohort. Continued follow up of the cohort is required to confirm excess mortality from bone tumours. PMID:9155782

  8. Occupational exposure to ionising radiation and mortality among workers of the former Spanish Nuclear Energy Board.

    PubMed

    Rodríguez Artalejo, F; Castaño Lara, S; de Andrés Manzano, B; García Ferruelo, M; Iglesias Martín, L; Calero, J R

    1997-03-01

    Firstly, to ascertain whether mortality among workers of the former Spanish Nuclear Energy Board (Junta de Energía Nuclear-JEN) was higher than that for the Spanish population overall; and secondly, if this were so, to ascertain whether this difference was associated with exposure to ionising radiation. A retrospective follow up of a cohort of 5657 workers was carried out for the period 1954-92. Cohort mortality was compared with that for the Spanish population overall, with standardised mortality ratios (SMRs) adjusted for sex, age, and calendar period. Also, Poisson models were used to analyse mortality from lung cancer in the cohort by level of exposure to ionising radiation. Workers' median and mean cumulative exposures were 4.04 and 11.42 mSv, respectively. Mean annual exposure was 1.33 mSv. Excess mortality due to bone tumours was found for the cohort as a whole (six deaths observed; SMR 2.95; 95% confidence interval (95% CI) 1.08 to 6.43). Among miners, excess mortality was found for non-malignant respiratory diseases (SMR 2.94; 95% CI 2.27 to 3.75), and for lung cancer bordering on statistical significance (SMR 1.50; 95% CI 0.96 to 2.23; P = 0.055). Relative risks of dying of lung cancer from ionising radiation in the dose quartiles 2, 3, and 4 versus the lowest dose quartile, were 1.00, 1.64, and 0.94, respectively. Excess mortality from lung cancer was found among JEN miners. Nevertheless, no clear relation was found between mortality from lung cancer and level of exposure to ionising radiation in the JEN cohort. Continued follow up of the cohort is required to confirm excess mortality from bone tumours.

  9. Do Facilitated Online Dual Credit Classes Result in Deep Learning?

    ERIC Educational Resources Information Center

    Stark Education Partnership, 2015

    2015-01-01

    This study, with funding from the Jennings Foundation, sought to answer the following broad research question: Do facilitated online dual credit courses result in deep learning? The answer to this question is key to addressing barriers many students face in bridging from high school to college. This report includes a descriptive case study that…

  10. A Content Analytic Study of "People's Daily" in Its Socialization Process: A Case in Cross-Cultural Communication.

    ERIC Educational Resources Information Center

    Marr, Theodore J.

    The author outlines a study comparing the modes of communication in two newspapers: "Jen Min Jih Pao" (People's Daily) and the Des Moines"Register." He applies a content-category system, based on Hayakawa's trichotomy of sentence types, to the reporting of these two newspapers on five major international events: the 1967 Arab-Israeli conflict, the…

  11. Economic Analysis of the Greenland Inland Traverse (GrIT)

    DTIC Science & Technology

    2016-06-01

    Weale of CRREL and that Randy Olsen, Gary Eells, Jen Mer- cer, and Scot Arnold provided on behalf of NSF-PLR. COL Bryan S. Green was Commander of ERDC...pontoons as lightweight, compliant suspensions be- tween HMW-PE sheets and wood -framed cargo decks. In 2012, GrIT de- ployed several tube-in-pouch ARCS

  12. The Creative Child

    ERIC Educational Resources Information Center

    Leader, Wendy

    2012-01-01

    Jen and Michael agreed that it felt like a mixed blessing when the kindergarten teacher told them she thought their daughter was "very creative." The teacher had commented on Allison's love of dramatic and imaginative play, her bold and expressive artwork, her knack for solving problems with numbers and shapes, and her delight in finding…

  13. Making Education Markets through Global Trade Agreements

    ERIC Educational Resources Information Center

    Robertson, Susan L.

    2017-01-01

    This paper uses the global trade negotiations and agreements, which include education sectors as potentially tradable services, to show the complex processes at work in making global education markets. Drawing on the work of Jens Beckert and others, I focus on the micro-processes of making capitalist orders and the challenges at hand in bringing…

  14. Aping Humanity--Scopes: A Tale of Two Titans of Law.

    ERIC Educational Resources Information Center

    Larson, Edward J.

    1999-01-01

    Describes the John Scopes case of 1925 in which he was tried and convicted for teaching evolution. Gives background on the two famous attorneys for the case: William Jennings Bryan and Clarence Darrow. Explains that the case turned into a media sensation because of the profound issues and oratory skills of the attorneys. (CMK)

  15. You're the Principal! Now What? Strategies and Solutions for New School Leaders

    ERIC Educational Resources Information Center

    Schwanke, Jen

    2016-01-01

    A principal's job is astonishingly complex, and its competing demands can be overwhelming, especially in the first few years. In this book, Jen Schwanke, a principal herself, provides a mentor's guidance to steer new principals through the period of adjustment and set the foundation for a long and rewarding career. The topics you wish your…

  16. Chicago's Columbus Park: The Prairie Idealized. Teaching with Historic Places.

    ERIC Educational Resources Information Center

    Bachrach, Julia Sniderman; Nathan, Jo Ann

    Twenty-four year old Jens Jensen came to the United States, settled in Chicago (Illinois), and promptly fell in love with the Midwest's prairie landscape. Although some thought that prairie was boring, monotonous, and ordinary, Jensen saw great beauty in the tree-filled groves, long winding rivers, natural rock formations and waterfalls, and the…

  17. KSC-98pc413

    NASA Image and Video Library

    1998-03-11

    KENNEDY SPACE CENTER, FLA. -- Ingo Ronny Wortmann (left) and Dr. Dirk Voeste, scientists with Ruhr-University of Bochum, Germany, examine swordtail fish (Xiphophorus helleri), like those that are part of the Neurolab payload on Space Shuttle Mission STS-90, in their holding tanks in the Operations and Checkout Building. The fish will fly in the Closed Equilibrated Biological Aquatic System (CEBAS) Minimodule, a middeck locker-sized freshwater habitat, designed to allow the controlled incubation of aquatic species in a self-stabilizing, artifical ecosystem for up to three weeks under space conditions. Investigations during the Neurolab mission will focus on the effects of microgravity on the nervous system. The crew of STS-90, slated for launch April 16 at 2:19 p.m. EDT, include Commander Richard Searfoss, Pilot Scott Altman, Mission Specialists Richard Linnehan, D.V.M., Dafydd (Dave) Williams, M.D., and Kathryn (Kay) Hire, and Payload Specialists Jay Buckey, M.D., and James Pawelczyk, Ph.D

  18. Swordtail fish fly on STS-90 as part of Neurolab

    NASA Technical Reports Server (NTRS)

    1998-01-01

    Ingo Ronny Wortmann (left) and Dr. Dirk Voeste, scientists with Ruhr-University of Bochum, Germany, examine swordtail fish (Xiphophorus helleri), like those that are part of the Neurolab payload on Space Shuttle Mission STS-90, in their holding tanks in the Operations and Checkout Building. The fish will fly in the Closed Equilibrated Biological Aquatic System (CEBAS) Minimodule, a middeck locker-sized freshwater habitat, designed to allow the controlled incubation of aquatic species in a self-stabilizing, artifical ecosystem for up to three weeks under space conditions. Investigations during the Neurolab mission will focus on the effects of microgravity on the nervous system. The crew of STS- 90, slated for launch April 16 at 2:19 p.m. EDT, include Commander Richard Searfoss, Pilot Scott Altman, Mission Specialists Richard Linnehan, D.V.M., Dafydd (Dave) Williams, M.D., and Kathryn (Kay) Hire, and Payload Specialists Jay Buckey, M.D., and James Pawelczyk, Ph.D.

  19. Slashes to Medicaid pose threat to PWAs.

    PubMed

    1995-01-01

    Congressional proposals are calling for cuts in Medicaid of up to $180 billion over the next 7 years. Because Medicaid is the largest source of health insurance for people living with HIV, the AIDS Action Council is educating policy makers about what is at stake. The Council's work has included testimony before the House Commerce Committee Subcommittee on Health and Environment and participation in a White House briefing on Medicaid sponsored by National AIDS Policy Director, Patsy Fleming, and Clinton's Special Assistant on Health Policy, Chris Jennings. At the briefing, Jennings assured participants that the President pledges to preserve Medicaid's entitlement status and keep cuts well under the Republicans' proposed cut of $182 billion. AIDS Action also prepared fact sheets for 10 states that detail the reliance of the HIV/AIDS community on Medicaid in each of those states. They are also supporting a postcard and telephone campaign organized by the Save Our Security Coalition (SOS), spearheaded by the health policy group Families USA. The postcards oppose Medicare and Medicaid cuts and ask the President to veto any such cuts.

  20. KSC-03PD-3146

    NASA Technical Reports Server (NTRS)

    2003-01-01

    KENNEDY SPACE CENTER, FLA. The Honorable Toni Jennings (left), lieutenant governor of the state of Florida, and Frank T. Brogan, president of Florida Atlantic University, receive a briefing on the research that will be conducted in the Space Life Sciences Lab from Dr. Robert J. Ferl (right), director of Space Agriculture Biotechnology Research and Education (SABRE), University of Florida. Jennings and Brogan are speaking at a dedication and ribbon-cutting ceremony for the lab hosted by NASA-Kennedy Space Center and the state of Florida at the new lab. Completed in August, the facility encompasses more than 100,000 square feet and was formerly known as the Space Experiment Research and Processing Laboratory or SERPL. The state, through the Florida Space Authority, built the research lab which is host to NASA, NASAs Life Sciences Services contractor Dynamac Corp., Bionetics Corp., and researchers from the University of Florida. Dynamac Corp. leases the facility. The Florida Space Research Institute is responsible for gaining additional tenants from outside the NASA community.

  1. Carboxylic Acids Plasma Membrane Transporters in Saccharomyces cerevisiae.

    PubMed

    Casal, Margarida; Queirós, Odília; Talaia, Gabriel; Ribas, David; Paiva, Sandra

    2016-01-01

    This chapter covers the functionally characterized plasma membrane carboxylic acids transporters Jen1, Ady2, Fps1 and Pdr12 in the yeast Saccharomyces cerevisiae, addressing also their homologues in other microorganisms, as filamentous fungi and bacteria. Carboxylic acids can either be transported into the cells, to be used as nutrients, or extruded in response to acid stress conditions. The secondary active transporters Jen1 and Ady2 can mediate the uptake of the anionic form of these substrates by a H(+)-symport mechanism. The undissociated form of carboxylic acids is lipid-soluble, crossing the plasma membrane by simple diffusion. Furthermore, acetic acid can also be transported by facilitated diffusion via Fps1 channel. At the cytoplasmic physiological pH, the anionic form of the acid prevails and it can be exported by the Pdr12 pump. This review will highlight the mechanisms involving carboxylic acids transporters, and the way they operate according to the yeast cell response to environmental changes, as carbon source availability, extracellular pH and acid stress conditions.

  2. [Mutagenic evaluation of the urine of rats treated with oils implicated in the toxic oil syndrome using bacterial tests].

    PubMed

    Barrueco, C; Sladek, F; Canga, C; Valcarce, E; de la Peña, E; Alia, M; Laborda, E

    1983-01-01

    The mutagenic activity of the urine of pregnant rats treated with toxic oil syndrome-related rape seed oil or with edible oil was evaluated by means of the Ames and Green tests. It was found that the urine of the pregnant rats treated with "Jen" oil, that was related to the toxic oil syndrome, was mutagenic.

  3. Fundamental Studies in the Molecular Basis of Laser Induced Retinal Damage.

    DTIC Science & Technology

    1984-09-01

    C. Hannemann , H. and Sochtig, E. (1979) Nature 277, 143-145. 25. Richards, J. M. and Swislocki, N. 1. (1979) J. Biol. Chem. 254, 6857-6860. 26...and Yamada, E. (1981) Biomedical Res. 2, 177-193. 51. Roof, D. J. and Heuser, J. E. (1982) J. Cell Biol. 95, 487-500. 52. Hagins, W. A. and Jennings , W

  4. Fundamental Studies in the Molecular Basis of Laser Induced Retinal Damage.

    DTIC Science & Technology

    1985-04-01

    J. -169. 25, 163-169. 24. Schwabe, U., Puchstein, C. Hannemann , H. and Sochtig, E. (1979) Nature 277, 143-145. 25. Richards, J. M. and Swislocki, N...Roof, D. J. and Heuser, J. E. (1982) J. Cell Biol. 95, 487-500. 52. Hagins, W. A. and Jennings , W. H. (1959) Discussion Faraday Soc. 27, 180-190. 53

  5. Taiwan-U.S. Political Relations: New Strains and Changes

    DTIC Science & Technology

    2006-10-10

    and KMT Representatives . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18 FAPA ... FAPA ), September 20, 2006. 12 Tkacik, John, “Strategy Deficit: America’s Security in the Pacific and Its Stake in Taiwan,” from a manuscript yet... FAPA , September 20, 2006. 58 Since 2000, the heads of the TECRO office in Washington have been C. J. (Chien-jen) Chen and David (Tawei) Li

  6. Emergency Nursing Review Questions: July 2017.

    PubMed

    Shaw, Tracy

    2017-07-01

    The review questions that are featured in each of issue of JEN are based on the Emergency Nursing Core Curriculum and other pertinent resources to emergency nursing practice, pediatric and adult. These questions offer emergency nurses an opportunity to test their knowledge about their practice. Copyright © 2017 Emergency Nurses Association. Published by Elsevier Inc. All rights reserved.

  7. Sweet Conclusion

    ERIC Educational Resources Information Center

    Shirley, Britt M.; Wooldridge, Barbara Ross; Camp, Kerri M.

    2012-01-01

    Jen Harrington is the owner and pastry chef of Sweet Conclusion, a bakery in Tampa, Florida. Most of Harrington's business comes from baking wedding cakes, but she has been attempting to attract customers to her retail bakery, where she sells cupcakes, pies, ice cream, and coffee. Nearly four years she opened Sweet Conclusion, the retail part of…

  8. Symposium on Molecular Spectroscopy (41st) Held in Columbus, Ohio on 16-20 June 1986.

    DTIC Science & Technology

    1986-06-21

    AND DIODE LASER SPECTROSCOPY OF GASES . ................................................................... 10 min.(8:30) . " NO D. E. JENNINGS, G. W...COLLISIONAL VELOCITY CHANGES ON LINE SHAPES OF HF BROADENED BY FOREIGN GASES ...............................................................15 m.(11:28...Facolta di Chimica Industriale , Universita di Venezia, Calle Larga S. Marta 2137, 1-30123 Venice, Italy; and H. REISENAUER, Institut fUr Organische

  9. On Staying with Our Students

    ERIC Educational Resources Information Center

    Jennings, Marianne

    2009-01-01

    This paper describes the author's experience and strategy in teaching business law and ethics. Jennings shares how business scandals have changed her three decades of teaching and describes how she has found a way of connecting with students by introducing some cognitive dissonance that stays with them when they are asked to do something in their…

  10. Evolution and Friendship

    ERIC Educational Resources Information Center

    Mena-Werth, Jose

    2005-01-01

    In 1925, Williams Jennings Bryan, a former congressman from Nebraska and a former Secretary of State under Woodrow Wilson, spent two agonizing weeks defending his religious faith that cost him his life a month after. Bryan was a prosecutor of high school teacher John Scopes, who had violated Tennessee state law by teaching the theory of evolution.…

  11. 1.3 micrometers Wavelength Vertical Cavity Surface Emitting Laser Fabricated by Orientation-Mismatched Wafer Bonding: A Prospect for Polarization Control

    DTIC Science & Technology

    2005-06-01

    mismatched wafer bonding: A prospect for polarization control Yae L. Okuno,a) Jon Geske , Kian-Giap Gan, Yi-Jen Chiu, Steven P. DenBaars, and John E. Bowers...Uomi, M. Aoki, and T. Tsuchiya, IEEE J. Quantum Electron. 33, 959 ~1997!. 20 Y. L. Okuno, J. Geske , Y.-J. Chiu, S. P. DenBaars, and J. E. Bowers, Proc

  12. Training Needs in Gerontology. Hearings, Special Committee on Aging, United States Senate. Part 1.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. Senate Special Committee on Aging.

    Two days of hearings on training needs in gerontology were opened by Senator Lawton Chiles. Statements were made by Senators Frank Church, Harrison A. Williams, Jr., Jennings Randolph, and Edward Kennedy. Witnesses for the first day were J. E. Wilson, III, with George Ebra and Maeve H. Foster; Walter M. Beattie; Percil Stanford; Clavin Fields with…

  13. The Ecological Domain of Warfare

    DTIC Science & Technology

    2004-06-01

    of military performance in terms of e.g., unpredictability, nonlinearity and self organized criticality. [4] The issues of complex interactions...WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Kockums AB,SE-371 82 Karlskrona,Sweden, , 8. PERFORMING ORGANIZATION REPORT...by the architechture for Open Computational Systems itself [Alberts & Hayes (2003)] Author: Jens-Olof Lindh, Security class: UNCLASSIFIED Status

  14. 75 FR 3455 - Union Electric Company dba Ameren/UE; Notice of Application for Amendment of License and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-21

    ... located at the Ozark Yacht Club near mile marker 0.8+0.6 in Jennings Branch Cove on the Lake of the Ozarks... of Request: The licensee requests approval to permit Ozark Yacht Club to construct a new 4-slip boat... for use by patrons of the Ozark Yacht Club. l. Locations of the Application: A copy of the application...

  15. Publisher Correction: Random access quantum information processors using multimode circuit quantum electrodynamics.

    PubMed

    Naik, R K; Leung, N; Chakram, S; Groszkowski, Peter; Lu, Y; Earnest, N; McKay, D C; Koch, Jens; Schuster, D I

    2018-01-09

    In the original version of this Article, the affiliation details for Peter Groszkowski and Jens Koch were incorrectly given as 'Department of Physics, University of Chicago, Chicago, IL, 60637, USA', instead of the correct 'Department of Physics and Astronomy, Northwestern University, Evanston, Illinois 60208, USA'. This has now been corrected in both the PDF and HTML versions of the Article.

  16. Preliminary digital geologic maps of the Mariposa, Kingman, Trona, and Death Valley Sheets, California

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    D`Agnese, F.A.; Faunt, C.C.; Turner, A.K.

    1995-10-01

    Parts of four 1:250,000-scale geologic maps by the California Department of Natural Resources, Division of Mines and Geology have been digitized for use in hydrogeologic characterization. These maps include the area of California between lat. 35{degree}N; Long. 115{degree}W and lat. 38{degree}N, long. 118{degree}W of the Kingman Sheet (Jennings, 1961), Trona Sheet (Jennings and others, 1962), Mariposa Sheet (Strand, 1967), and Death Valley Sheet (Streitz and Stinson, 1974). These digital maps are being released by the US Geological Survey in the ARC/INFO Version 6.1 Export format. The digitized data include geologic unit boundaries, fault traces, and identity of geologic units. Themore » procedure outlined in US Geological Survey Circular 1054 (Soller and others, 1990) was sued during the map construction. The procedure involves transferring hard-copy data into digital format by scanning manuscript maps, manipulating the digital map data, and outputting the data. Most of the work was done using Environmental Systems Research Institute`s ARC/INFO software. The digital maps are available in ARC/INFO Rev. 6.1 Export format, from the USGS, Yucca Mountain Project, in Denver, Colorado.« less

  17. Enhanced, Partially Redundant Emergency Notification System

    NASA Technical Reports Server (NTRS)

    Pounds, Clark D.

    2005-01-01

    The Johnson Space Center Emergency Notification System (JENS) software utilizes pre-existing computation and communication infrastructure to augment a prior variable-tone, siren-based, outdoor alarm system, in order to enhance the ability to give notice of emergencies to employees working in multiple buildings. The JENS software includes a component that implements an administrative Web site. Administrators can grant and deny access to the administrative site and to an originator Web site that enables authorized individuals to quickly compose and issue alarms. The originator site also facilitates maintenance and review of alarms already issued. A custom client/server application program enables an originator to notify every user who is logged in on a Microsoft Windows-based desktop computer by means of a pop-up message that interrupts, but does not disrupt, the user s work. Alternatively or in addition, the originator can send an alarm message to recipients on an e-mail distribution list and/or can post the notice on an internal Web site. An alarm message can consist of (1) text describing the emergency and suggesting a course of action and (2) a replica of the corresponding audible outdoor alarm.

  18. A practical tool for monitoring the performance of measuring systems in a laboratory network: report of an ACB Working Group.

    PubMed

    Ayling, Pete; Hill, Robert; Jassam, Nuthar; Kallner, Anders; Khatami, Zahra

    2017-11-01

    Background A logical consequence of the introduction of robotics and high-capacity analysers has seen a consolidation to larger units. This requires new structures and quality systems to ensure that laboratories deliver consistent and comparable results. Methods A spreadsheet program was designed to accommodate results from up to 12 different instruments/laboratories and present IQC data, i.e. Levey-Jennings and Youden plots and comprehensive numerical tables of the performance of each item. Input of data was made possible by a 'data loader' by which IQC data from the individual instruments could be transferred to the spreadsheet program on line. Results A set of real data from laboratories is used to populate the data loader and the networking software program. Examples are present from the analysis of variance components, the Levey-Jennings and Youden plots. Conclusions This report presents a software package that allows the simultaneous management and detailed monitoring of the performance of up to 12 different instruments/laboratories in a fully interactive mode. The system allows a quality manager of networked laboratories to have a continuous updated overview of the performance. This software package has been made available at the ACB website.

  19. The Geomorphic System and the Effects of Human Interference at Gold Coast Beach in Tainan, Taiwan

    NASA Astrophysics Data System (ADS)

    Lin, Tsung-Yi

    2017-04-01

    The Gold Coast beach in Tainan, Taiwan, located between Anping harbor and Ur-Jen river mouth, is the subject of this study, which characterizes the beach's geomorphic system through the analysis of information such as sediment grain size, mineral composition, and periodic measurements of morphological changes of the beach. Based upon such characterizations, further analysis is conducted on the effects that human activities of the last 15 years have upon the geomorphic changes within the Gold Coast beach. The study shows that the median grain size of the Gold Coast beach's sediment is medium sand. The mineral composition includes mainly slate fragments and quartz grains, with small amounts of feldspar, sandstone and shell fragments. Based on a comprehensive study of the longshore distribution of beach sediment size and mineral composition of southwestern coast of Taiwan, as well as, the long-term, monitored data of waves, tides, and currents in this region, we conclude that the main process responsible for the sand accumulation at Gold Coast beach is the prevailing longshore sand transport from south to north. The southern breakwater of Anping harbor plays a role in intercepting the longshore transport sand and helps form the beach. Since the Ur-Jen river flows through a mudstone region, the suspended sediment plume during the flood season does not provide much sediment source to the sandy beach. A monthly beach profile survey project conducted between the years 1999 to 2000 revealed that the beach elevation and width had experienced an obvious seasonal change. The beach widened during the winter, but narrowed in the summer due to typhoon wave erosion. When the subaerial beach was eroded, a submerged longshore bar that was oriented almost parallel to the shoreline had formed at a distance about 400-600 meter away. With this observation, we can conclude that beach morphology is also influenced by various seasonal wave actions that affect onshore and offshore sand

  20. Doppler Imaging with FUSE: The Partially Eclipsing Binary VW Cep

    NASA Technical Reports Server (NTRS)

    Sonneborn, George (Technical Monitor); Brickhouse, Nancy

    2003-01-01

    This report covers the FUSE Guest Observer program. This project involves the study of emission line profiles for the partially eclipsing, rapidly rotating binary system VW Cep. Active regions on the surface of the star(s) produce observable line shifts as the stars move with respect to the observer. By studying the time-dependence of the line profile changes and centroid shifts, one can determine the location of the activity. FUSE spectra were obtained by the P.I. 27 Sept 2002 and data reduction is in progress. Since we are interested in line profile analysis, we are now investigating the wavelength scale calibration in some detail. We have also obtained and are analyzing Chandra data in order to compare the X-ray velocities with the FUV velocities. A complementary project comparing X-ray and Far UltraViolet (FUV) emission for the similar system 44i Boo is also underway. Postdoctoral fellow Ronnie Hoogerwerf has joined the investigation team and will perform the data analysis, once the calibration is optimized.

  1. Lineaments and fracture traces, Jennings County and Jefferson Proving Ground, Indiana

    USGS Publications Warehouse

    Greeman, T.K.

    1981-01-01

    Well placement is important in this area, as fractures are a principal source of water to wells. In areas of fractured bedrock, the most productive well locations are at the intersections of two or more mapped lineaments or fracture traces and at the lowest local altitude. Use of the lineament and fracture-trace map will not guarantee a sufficent supply of ground water but will minimize the chance of drilling an inadequate well.

  2. Donkey in Disguise: Jack Jennings and the Center on Education Policy

    ERIC Educational Resources Information Center

    Forster, Greg

    2006-01-01

    With the passage of the No Child Left Behind Act (NCLB), the proliferation of high school exit exams, the success of school choice initiatives, and a dozen other smaller if more bitter battles, education has become one of the hottest policy topics in Washington. That means there is a booming market for education experts, especially those who claim…

  3. Characterizing and Targeting Replication Stress Response Defects in Breast Cancer

    DTIC Science & Technology

    2015-08-01

    1 AD_________________ Award Number: W81XWH-10-1-0558 TITLE: Characterizing and Targeting Replication Stress Response Defects in Breast Cancer ...PRINCIPAL INVESTIGATOR: Shiaw-Yih Lin, Ph.D. CONTRACTING ORGANIZATION: University of Texas M. D. Anderson Cancer Center Houston, TX 77030 REPORT...Response Defects in Breast Cancer 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Betty Diamond 5d. PROJECT NUMBER Chun-Jen Lin, Hui Dai

  4. Transformation and Transition: DARPA’s Role in Fostering an Emerging Revolution in Military Affairs. Volume 2- Detailed Assessments

    DTIC Science & Technology

    2003-11-01

    the basis of the overall assessment. The authors wish to thank John Jennings, the DARPA task manager for this project, for his detailed review and...comments on all of the chapters in this volume. His review led to greatly improved clarity on our part in both depicting the flow of technology...are solely those of the authors and not the contributors, reviewers , or current DARPA management. v CONTENTS Preface

  5. Bridenstine Sworn In As NASA Administrator

    NASA Image and Video Library

    2018-04-23

    Jen Rae Wang, NASA Associate Administrator for NASA’s Office of Communications, left, NASA Administrator Jim Bridenstine, and Vice President Mike Pence, talk with NASA astronauts Scott Tingle, Andrew Feustel, and Ricky Arnold who are onboard the International Space Station, Monday, April 23, 2018 at NASA Headquarters in Washington. Bridenstine was just sworn in by the Vice President as NASA's 13th Administrator. Photo Credit: (NASA/Joel Kowsky)

  6. NUCLEAR ENERGY COMMISSION, HIGHER COUNCIL OF RESEARCH, AND THE CENTER OF RESEARCH IN PHYSICS IN MADRID, SPAIN.

    DTIC Science & Technology

    and controls essentially all aspects of scientific research in Spain, and the Centro de Investigaciones Fisicas (CIF) ’Leonardo Torres Quevedo,’ a...Commission; the Consejo Superior de Investigaciones Cientificas (CSIC) or Higher Council of Scientific Research, which is the governing body that administers...The report gives an account of a liasion visit to three institutions in Madrid: the Junta de la Energia Nuclear (JEN), Spain’s Nuclear Energy

  7. Chemotherapy of Rodent Malaria. Part 1.

    DTIC Science & Technology

    1986-09-01

    r-.-n r ri it ,i n’ reat u i m t. i u r , o , eck f ’ aIny b: e interfe r e ,r.r Orn t tn. - References: 1. Mii l , * ii,? ta’,on . . .. (1d85) rd . i...Center (DTIC) ATTN: DTIC-DDAC Cameron Station Alexandria, VA 22304-6145 copy jen .cf ool of Miedicine ninformed Servies Univercit, of the H,-1it

  8. A Model for the Evaluation of Offsets in International Arms Transfers.

    DTIC Science & Technology

    1982-01-01

    8tefan a. Robock and Kenneth Sizmonds, International Business and Multinational Entergrises (Wamewood, Illinois: Richard D. Irwin, Inc., 1973)., pp. 70-73...individual voter is socialized into his political attitudes, not, as Sir Ivor Jennings suggested, on casting his first vote, nor at the moment of birth...N.J.: Prentice-Hall, 1974. Branson , William H. Macroeconomic Theory and Policy. New York: Harper and Row Publishers, 1972. Carlton, David and Carlo

  9. Aerial Refueling For NATO’s Smart Defence Initiative

    DTIC Science & Technology

    2012-04-01

    Rome: NATO Defense College, 2012, 148. 40 David A. Brown , "NATO Studying Development of Dedicated Refueling Unit Similar to Early Warning Force...accessed March 1, 2012). Brown , David A. "NATO Studying Development of Dedicated Refueling Unit Similar to Early Warning Force." Aviation Week...Aircraft. Coulsdon, Surrey: IHS Global Limited, 2011. Jennings, Gareth . "Nations Pool for NATO C-17A Fleet." Jane’s Defence Weekly, October 2008

  10. Optimizing Airborne Networking Performance with Cross-Layer Design Approach

    DTIC Science & Technology

    2009-06-01

    Schiavone , L.J.; “Airborne Networking –Approaches and Challenges,” Military Communications Conference IEEE, Oct 31 – Nov 3, 2004, Vol. 1, pp. 404...www.ccny.cuny.edu/cint/ [5] John Seguí and Esther Jennings,’’ Delay Tolerant Networking – Bundle Protocol Simulation’’ [6] DTNRG website...throughput route selection in multi-rate ad hoc wireless networks,” Technical report, Johns Hopkins CS Dept, March 2003. v 2. [15] R. Draves, J

  11. Annotated Bibliography for Lake Erie. Volume I. Biological,

    DTIC Science & Technology

    1974-10-01

    varieties of naiades from I Lake Erie . Nautilus. 32(l):9-12. Three new varieties of naiades collected at Presque Isle , Pennsylvania are carefully...E. 1909. A botanical survey of Presque Isle , Erie County, Pennsylvania . Annals Carnegie Mus. Pittsburgh, Penn. Pub. 53. 5(l):2 9-421. This study...of vegetation on Presque Isle . (SM) 401. Jennings, Otto E. 1930. A survey of the phytoplankton at Erie , Pennsylvania . Science. 71(1848):560-61. A

  12. An Evolving Joint Acquisition Force

    DTIC Science & Technology

    2004-03-19

    COVERED - 4. TITLE AND SUBTITLE An Evolving Joint Acquisition Force 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR( S ...Theodore Jennings 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME( S ) AND ADDRESS(ES) U.S. Army War...College,Carlisle Barracks,Carlisle,PA,17013-5050 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY NAME( S ) AND ADDRESS(ES) 10

  13. Identification and Pathological Characterization of Persistent Asymptomatic Ebola Virus infection in Rhesus Monkeys

    DTIC Science & Technology

    2017-05-12

    and Use of Laboratory Animals, National 508 Research Council, 2011. 509 Author contributions 510 X.Z. conceived and designed the experiments. X.Z...Dye 1 , Sina Bavari 1 , 5 Gustavo Palacios 1 , Jens H. Kuhn 2 , Mei G. Sun 1 6 7 1 United States Army Medical Research Institute of Infectious...Diseases, 1425 Porter 8 Street, Fort Detrick, Frederick, Maryland 21702, USA; 2 Integrated Research Facility at 9 Fort Detrick, National Institute of

  14. Let Slip the Dogs of (CYBER) War: Progressing Towards a Warfighting U.S. Cyber Command

    DTIC Science & Technology

    2013-04-01

    Accelerating Cyberweapon Reseach ,” Washington Post , 18 March 2012. 20 Federal Bureau of Investigation, “What we Investigate - Cyber Crime,” http...on- uk-police-s-anti-terror-hotline (accessed 2 January 2013). 18 Jen Lin-Liu, “Huawei-Cisco Tests China’s Respect for Property Rights,” IEEE... designated as critical infrastructure (CI).19 Securing this CI will be a challenge: most is privately vice publicly owned, and there is limited incentive

  15. Enemies within: Christian Extremism, a Threat to the Homeland

    DTIC Science & Technology

    2016-06-10

    the time of his death, the movement vigorously developed in California, and clearly separated itself from its English roots. By the 1990s, two new...Mr. Jennings for their dedicated commitment to the development of this thesis. Your cumulative experience, knowledge and mentorship proved vital and...privileged to have developed this thesis under the tutelage of such wise leaders and thank you sincerely for a product that will serve as a changing

  16. Correlations Between Micromagnetic, Microstructural and Microchemical Properties in Ultrathin Epitaxial Magnetic Structures

    DTIC Science & Technology

    1993-12-31

    substrates. 2-17,19- 24-17-34 These films possess corn- temperature. It is the complexity of both the structural and plec two-dimensional magnetic...free energy differences, diffusion lengths,were taken to ensure that these measurements represent su~ rt tepraue and deposition rates. At room tern...Arnion, G. Jennings, and Rt F. Willis, Surface taneous multilayered growth made due to the lack of Science 192, LS43 (1987). breaks in the normalized MWV

  17. An Archeological Overview and Management Plan for Tooele Army Depot North and South

    DTIC Science & Technology

    1984-03-29

    1978, Heizer and Krieger 1956, Heizer and Harper 1970, and Warren and Ranere 1968). Over the years, Jennings (1974) has modified his Desert Culture...received special supernatural power that would capture the animals’ souls, rendering them docile and stupid (Steward 1970:34). Other large game was present...nomination Form: "Great Basin Style rock art is primarily a petroglyph style, originally defined by Julian Steward (1929) and aescribed in detail by Heizer

  18. Optical Computing. Organization of the 1993 Photonics Science Topical Meetings Held in Palm Springs, California on March 16 - 19, 1993. Technical Digest Series, Volume 7

    DTIC Science & Technology

    1993-03-19

    network Implementation using 9:20 am asymmetric Fabry-Perot modulators, Andrew Jennings, Brian OWA3 Multiwavelength optical half adder, Pochi Yeh... multiwavelength optical half adder. (p. 68) nects. (p. 96) 9:40 am 2:50 pm OWA4 Wavelength multiplexed computer-generated volume OWC3 Content addramble...ATMOS and OSCAR are RACE projects, mentioned in the text shape this into new systems architectures, ("optical ether"). Broadly speaking, this has led to

  19. Simulation of Locking Space Truss Deployments for a Large Deployable Sparse Aperture Reflector

    DTIC Science & Technology

    2015-03-01

    Dr. Alan Jennings, for his unending patience with my struggles through this entire process . Without his expertise, guidance, and trust I would have...engineer since they are not automatically meshed. Fortunately, the mesh process is quite swift. Figure 13 shows both a linear hexahedral element as well...less than that of the serial process . Therefore, COMSOL’s partially parallelized algorithms will not be sped up as a function of cores added and is

  20. An Analysis of the Navy’s Fiscal Year 2012 Shipbuilding Plan

    DTIC Science & Technology

    2011-06-01

    Documentation Page Form ApprovedOMB No. 0704-0188 Public reporting burden for the collection of information is estimated to average 1 hour per response...penalty for failing to comply with a collection of information if it does not display a currently valid OMB control number. 1 . REPORT DATE JUN 2011 2...Raymond Hall of CBO’s Budget Analysis Division produced the cost estimates under the general supervision of Sarah Jennings . Bernard Kempinski

  1. Jenner-predict server: prediction of protein vaccine candidates (PVCs) in bacteria based on host-pathogen interactions

    PubMed Central

    2013-01-01

    Background Subunit vaccines based on recombinant proteins have been effective in preventing infectious diseases and are expected to meet the demands of future vaccine development. Computational approach, especially reverse vaccinology (RV) method has enormous potential for identification of protein vaccine candidates (PVCs) from a proteome. The existing protective antigen prediction software and web servers have low prediction accuracy leading to limited applications for vaccine development. Besides machine learning techniques, those software and web servers have considered only protein’s adhesin-likeliness as criterion for identification of PVCs. Several non-adhesin functional classes of proteins involved in host-pathogen interactions and pathogenesis are known to provide protection against bacterial infections. Therefore, knowledge of bacterial pathogenesis has potential to identify PVCs. Results A web server, Jenner-Predict, has been developed for prediction of PVCs from proteomes of bacterial pathogens. The web server targets host-pathogen interactions and pathogenesis by considering known functional domains from protein classes such as adhesin, virulence, invasin, porin, flagellin, colonization, toxin, choline-binding, penicillin-binding, transferring-binding, fibronectin-binding and solute-binding. It predicts non-cytosolic proteins containing above domains as PVCs. It also provides vaccine potential of PVCs in terms of their possible immunogenicity by comparing with experimentally known IEDB epitopes, absence of autoimmunity and conservation in different strains. Predicted PVCs are prioritized so that only few prospective PVCs could be validated experimentally. The performance of web server was evaluated against known protective antigens from diverse classes of bacteria reported in Protegen database and datasets used for VaxiJen server development. The web server efficiently predicted known vaccine candidates reported from Streptococcus pneumoniae and

  2. C2 Failures: A Taxonomy and Analysis

    DTIC Science & Technology

    2013-06-01

    2, pp. 171-199. Huber, Reiner, Tor Langsaeter, Petra Eggenhofer, Fernando Freire, Antonio Grilo, Anne-Marie Grisogono, Jose Martine , Jens Roemer... Martin (2012). Mission Command White Paper. Washington, D.C.: U.S. Department of Defense, Office of the Chairman of the Joint Chiefs of Staff. http...e1352384704110.jpeg?w=625&h=389 The Punchline “What we’ve got here, is failure to communicate” Strother Martin as “The Captain,” Cool Hand Luke, (Warner

  3. Boeing Michigan Aeronautical Research Center (BOMARC) Missile Shelters and Bunkers Scoping Survey Report

    DTIC Science & Technology

    2009-06-01

    support for surveys – Capt Annheng Jen, SSgt Shayne Miller, SSgt Delaney Green, SSgt Amanda Aldaco, SSgt Ashlie Steele, SrA Jasmine Rosario, A1C...removable fraction considered, this same condition will exists for a 2.4 % removable fraction. In essence , for the 239+240Pu and 241Am surface contaminant...SrA Jasmine Rosario Survey Time: 12:00 to 13:47 Shelter Number: 205 Survey Instruments: 1) Ludlum 2224 (S/N 125659) 1) Ludlum 43-89

  4. U.S.-China Military Contacts: Issues for Congress

    DTIC Science & Technology

    2010-12-14

    of Defense Dick Cheney, alleging that “several dozen” American military personnel captured in the Korean War (1950- 1953 ) were sent to a camp in the...agreed to look into the U.S. request to access the archives .103 In March 2003, DPMO Director Jerry Jennings visited China and said that PRC records ...its archives on the PRC’s foreign relations from 1949 to 1955. However, this step apparently excluded wartime records , and General Myers did not

  5. U.S.-China Military Contacts: Issues for Congress

    DTIC Science & Technology

    2010-07-22

    then Secretary of Defense Dick Cheney, alleging that “several dozen” American military personnel captured in the Korean War (1950- 1953 ) were sent...U.S. request to access the archives .97 In March 2003, DPMO Director Jerry Jennings visited China and said that PRC records likely hold “the key...files in its archives on the PRC’s foreign relations from 1949 to 1955. However, this step apparently excluded wartime records , and General Myers did not

  6. U.S.-China Military Contacts: Issues for Congress

    DTIC Science & Technology

    2010-07-06

    of Defense Dick Cheney, alleging that “several dozen” American military personnel captured in the Korean War (1950- 1953 ) were sent to a camp in the...request to access the archives .96 In March 2003, DPMO Director Jerry Jennings visited China and said that PRC records likely hold “the key” to...China finally agreed to allow access to the PLA archives on the Korean War. However, the PLA did not grant direct access to the records , as asked

  7. International Symposium on Analysis and Detection of Explosives (4th) Held in Jerusalem, Israel on September 7 - 10, 1992. Programs and Abstracts

    DTIC Science & Technology

    1992-09-01

    chromatography. * DI EXPLOSIVE ANALYSIS USING CAPILLARY ELECTROPHORESIS Bruce R . McCord., Forensic Science Research Unit, FBI Academy, Quantico, VA...gel and emulsion explosives E. Bender, R . Strobel, and C.R. Midkiff. Ir, Bureau of ATF, Rockville, MD, USA 11.05 D3 The analysis of the explosives of...organic substrates . . - r __ A.D. Wright, K.R. Jennings and R . Peters, University of Warwick, Coventry, U.K. 16:40 F2 GC/MS analysis of PETN and NG

  8. Some Optical Properties of Blowing Snow.

    DTIC Science & Technology

    1981-06-01

    TR-0058, May 1980. 130. Heaps, Melvin G., Robert 0. Olsen, Warren Berning, John Cross, and Arthur Gilcrease, 񓟛 Solar Eclipse, Part I - Atmospheric...Near-Millimeter Wave (NMMW) 9ronacation Measurements," ASL-T.-OC63, August 1980. 135. Bruce, Charles W., Young Paul Yee, and S. G. Jennings, "In Situ...Measurement of the Ratio of Aerosol Absorption to Extinction Coefficient," ASL-TR-0064, August 1980. 136. Yee, Young Paul , Charles W. Bruce, and Ralph J

  9. Targeted Silver Nanoparticles for Dual-Energy Breast X-Ray Imaging

    DTIC Science & Technology

    2013-03-01

    imaging parameters. In addition, Ag performs better than I when imaging at the optimal conditions for I. For example, using a rhodium filter, the...Laboratory. XCOM: Photon Cross Sections Database. Retrieved December 10, 2011 2. Boone J.M. , Fewell, T.R., Jennings, R.J. Molybdenum, rhodium , and tungsten...and a 27 kVp low-energy beam with rhodium filtration, at a dose distribution of 50:50. This low-energy technique is a classic example of an

  10. An Investigation of the Effects of Discrete Wing Tip Jets on Wake Vortex Roll Up.

    DTIC Science & Technology

    1983-08-01

    failure of these devices does not mean that the vortex structure cannot be altered such as to reduce rolling moment. On the contrary, Yuan and Bloom (43...which has demonstrated a capabilitv, to e:ra induced rolling moment - the downward blowing jet of .𔄁, ,and Bloom (43)- was also the only jet...eliminated the large vortex excursions associated with close approaches. Bloom and Jen (83) used the method of Kuwahara and Takami to calculate vortex roll up

  11. Aircraft Observations for Improved Physical Parameterization for Seasonal Prediction

    DTIC Science & Technology

    2013-09-30

    platform is ready for use in air-sea interaction research projects. RELATED PROJECTS None PUBLICATIONS Gerber H., G. Frick, S. Malinowski ... Malinowski , S. P., H. Gerber, I. Jen-LaPlante, M. K. Kopec, W. Kumala, K. Nurowska, P. Y. Chuang, K. E. Haman, D. D. Khelif, S. K. Krueger, and H. H. Jonsson...Haman, K. E., Kopec, M. K., Khelif, D., and Malinowski , S. P.: Modified ultrafast thermometer UFT-M and temperature measurements during Physics of

  12. Translations of JEN-MIN JIH-PAO Articles on Sociological and Economic Subjects

    DTIC Science & Technology

    1960-06-23

    atmosphere filled, with fiery enthusiasm and the spirit of realism . kchie ver/ients At fcributabie_to_Poli^ios^SBjirning Taking for example the...but also gradually achieved good -quality. The stage play is different from the cinematic film. At the beginning of its performance, there might...forward the combination of revolutionary realism with revolutionary romaticism, &t-<x this is a creative method’which is in keeping with the spirt

  13. Space Shuttle Program

    NASA Image and Video Library

    2012-09-12

    Ronnie Rigney (r), chief of the Propulsion Test Office in the Project Directorate at Stennis Space Center, stands with agency colleagues to receive the prestigious American Institute of Aeronautics and Astronautics George M. Low Space Transportation Award on Sept. 12. Rigney accepted the award on behalf of the NASA and contractor team at Stennis for their support of the Space Shuttle Program that ended last summer. From 1975 to 2009, Stennis Space Center tested every main engine used to power 135 space shuttle missions. Stennis continued to provide flight support services through the end of the Space Shuttle Program in July 2011. The center also supported transition and retirement of shuttle hardware and assets through September 2012. The 2012 award was presented to the space shuttle team 'for excellence in the conception, development, test, operation and retirement of the world's first and only reusable space transportation system.' Joining Rigney for the award ceremony at the 2012 AIAA Conference in Pasadena, Calif., were: (l to r) Allison Zuniga, NASA Headquarters; Michael Griffin, former NASA administrator; Don Noah, Johnson Space Center in Houston; Steve Cash, Marshall Space Flight Center in Huntsville, Ala.; and Pete Nickolenko, Kennedy Space Center in Florida.

  14. Habitat Preference, Dispersal, and Population Trends of Three Species of Invasive Asian Carps in Tributaries of the La Grange Reach of the Illinois River

    DTIC Science & Technology

    2012-07-01

    Open circles represent sampling sites. Closed black circles indicate sampling sites at which Asian carp were collected. Closed brown circles...steelhead trout . Ecology 82(5):1247–1259. Kolar, C. S., D. C. Chapman, W. R. Courtenay, Jr., C. M. Housel, J. D. Williams, and D. P. Jennings. 2005...Resh, V. H., A. V. Brown , A. P. Covich, M. E. Gurtz, H. W. Li, G. W. Minshall, S. R. Reice, A. L. Shelden, J. B. Wallace, and R. C. Wissmar. 1988. The

  15. Characterizing and Targeting Replication Stress Response Defects in Breast Cancer

    DTIC Science & Technology

    2014-08-01

    NUMBER Shiaw-Yih Lin , Chun-Jen Lin, Lili Gong, Hui Dai, Ju-Seog Lee 5e. TASK NUMBER E-Mail: sylin@mdanderson.org The University of...the mammary fat pads of female nude mice. We closely monitored tumor formation in the mice. Notably, tumors began to form in 3 of 10 mice injected...and two independent TUSC4-knockdown MCF-10A cell lines (TUSC4 #1 and TUSC4 #4) were injected per mouse into mammary fat pads of 6-week-old female nude

  16. KAM Torus Orbit Prediction from Two Line Element Sets

    DTIC Science & Technology

    2014-03-01

    should be addressed. KAM Theory, SGP4 and TLE, Periodic Orbit, Floquet Problem, Non-linear Least Squares U U U UU 138 Dr William E. Wiesel Jr . (ENY) (937) 255-3636 x4312 william.wielsel@afit.edu ...UNIVERSITY AIR FORCE INSTITUTE OF TECHNOLOGY Wright- Patterson Air Force Base, Ohio DISTRIBUTION STATEMENT A APPROVED FOR PUBLIC RELEASE; DISTRIBUTION...ABAY, BS 1st Lieutenant, TURAF Approved: //signed// Feb 28, 2014 William E. Wiesel, PhD (Chairman) Date //signed// Feb 28, 2014 Alan L. Jennings, PhD

  17. Joint Summer Research Conferences in the Mathematical Sciences, Held at Seattle, Washington on 22 June-2 August 1991

    DTIC Science & Technology

    1991-08-02

    1991 Budget total $38,000.00 Committed funds 38,688.20 (688.20) Participant Attend Subsistence Travel Total Check Jorgensen, Leif K. yes 0 Jung , Heinz A...Korach, Ephraim yes 529.20 529.20 Kratochvil, Jan yes 550.00 550.00 $530 Kung, Joseph P. yes 0 Kuo , Yueh-er no 0 L.agergren, Jens yes 0 Lai, Hong-Jian...Seress, Akos yes 529.20 529.20 Seymour, Paul yes 0 Wang, Shang-Zhi yes 451.20 451.20 Shih , Ching-Hsien no 0 Simpson, Stephen yes Siran, Josef yes

  18. In Situ Soil Venting - Full Scale Test Hill AFB, Guidance Document, Literature Review. Volume 1

    DTIC Science & Technology

    1991-08-01

    AD-A254 924 1’) VOL I IN SITU SOIL VENTING - FULL SCALE TEST HILL AFB, GUIDANCE DOCUMENT, LITERATURE REVIEW D. W. DEPAO, S. E. HERBES, J. H . WILSON...D. K. SOLOMON, AND H . L. JENNINGS MARTIN-MARIETTA ENERGY SYSTEMS OAK RIDGE NATIONAL LABORATORY P. O. BOX 2008 OAK RIDGE TN 37831 OTI AUGUST 1991 S...sificat,cn) (U) In Situ Soil Ver.ting - Full Scale Test Hill AFB, Guidance Document, Literature Review 2 PERSO’.AL AUTH-O’.S, a W ApP li- S_ T’.- erber:. H

  19. Live from Antarctica: Then and now

    NASA Astrophysics Data System (ADS)

    This real-time educational video series, featuring Camille Jennings from Maryland Public Television, includes information from Antarctic scientists and interactive discussion between the scientists and school children from both Maryland and Hawaii. This is part of a 'Passport to Knowledge Special' series. In this part of the four part Antarctic series, the history of Antarctica from its founding to the present, its mammals, plants, and other life forms are shown and discussed. The importance of Antarctica as a research facility is explained, along with different experiments and research that the facilities there perform.

  20. Live from Antarctica: Then and Now

    NASA Technical Reports Server (NTRS)

    1994-01-01

    This real-time educational video series, featuring Camille Jennings from Maryland Public Television, includes information from Antarctic scientists and interactive discussion between the scientists and school children from both Maryland and Hawaii. This is part of a 'Passport to Knowledge Special' series. In this part of the four part Antarctic series, the history of Antarctica from its founding to the present, its mammals, plants, and other life forms are shown and discussed. The importance of Antarctica as a research facility is explained, along with different experiments and research that the facilities there perform.

  1. Energy Storage As Heat-of-Fusion in Containerized Salts.

    DTIC Science & Technology

    1980-06-27

    4 ) LuZ 0: 1 W Lu w OL~u 0 r 00 -: o - 0 0 4 zz = 0 . (J 074)o w V > b Lu 0 w 0- > 0 -J 12E- x NRL MEMORANDUM REPORT 4267 superheater functions. These...las mezclas terfenili- cas comerciales,* J.E.N. 123 DQ/137. (Junta de Energia Nuclear, Ciudad Universitaria, Madrid, Spain) F2. Rhone-Poulenc...ael itself will be contained in thin wall sltel cns of 105 mm diameter and 4) Unlike sit that sol in dry nitrogen, the 18.tmc cycled •-yet.unpeciled

  2. Signatures of the electron saddle swaps mechanism in the photon spectra following charge-exchange collisions

    NASA Astrophysics Data System (ADS)

    Otranto, Sebastian

    2014-10-01

    During the last few years, several experimental and theoretical studies have focused on state selective charge exchange processes between charged ions and alkali metals. These data are of particular importance for the tokamak nuclear fusion reactor program, since diagnostics on the plasma usually rely on charge-exchange spectroscopy. In this sense, alkali metals, have been proposed as potential alternatives to excited hydrogen/deuterium for which laboratory experiments are not feasible at present. In this talk, we present our recent work involving ion collisions with alkali metals. Oscillatory structures in the angular differential charge-exchange cross sections obtained using the MOTRIMS technique are correctly described by classical trajectory Monte Carlo simulations. These oscillations are found to originate from the number of swaps the electron undergoes around the projectile-target potential saddle before capture takes place and are very prominent at impact energies below 10 keV/amu. Moreover, cross sections of higher order of differentiability also indicate that the swaps leave distinctive signatures in the (n,l)-state selective cross sections and in the photon line emission cross sections. Oscillatory structures for the x-ray hardness ratio parameter are also predicted. In collaboration with Ronnie Hoekstra, Zernike Institute for Advanced Materials, University of Groningen and Ronald Olson, Department of Physics, Missouri University of Science and Technology.

  3. 'National Hero and Very Queer Fish': Empire, Sexuality and the British Remembrance of General Gordon, 1918-72.

    PubMed

    Jones, Max

    2015-01-01

    This article presents the first detailed study of General Gordon's remembrance in Britain between 1918 and 1972. Previous scholars have exaggerated the impact of Lytton Strachey's Eminent Victorians (1918). Strachey damaged Gordon's reputation, but part one reveals how several commentators forcefully rebutted Eminent Victorians; official commemorations, books, radio plays, and films celebrated Gordon in the 1930s, as empire featured prominently in mass culture. Didactic uses of his example by the state diminished after 1945, but parts 2 and 3 show how writers used Gordon's story to engage with new debates about Britain's role in the world, immigration and sexuality. The article reveals how a fascination with the sexuality of heroes inspired men as diverse as Viscount Robin Maugham and East End gangster Ronnie Kray to identify with Gordon. Maugham's works and the feature film Khartoum (1966) expressed nostalgia for empire during decolonization, but American screenwriter Robert Ardrey also drew on his experiences in the Congo to present a dark vision of African savagery in Khartoum, a vision performed at Pinewood studios by black immigrants from London's slums. The article questions Edward Berenson's emphasis on the 'charismatic aura' of heroes, emphasizing instead the diversity of engagements inspired through different genre.

  4. DRREP: deep ridge regressed epitope predictor.

    PubMed

    Sher, Gene; Zhi, Degui; Zhang, Shaojie

    2017-10-03

    The ability to predict epitopes plays an enormous role in vaccine development in terms of our ability to zero in on where to do a more thorough in-vivo analysis of the protein in question. Though for the past decade there have been numerous advancements and improvements in epitope prediction, on average the best benchmark prediction accuracies are still only around 60%. New machine learning algorithms have arisen within the domain of deep learning, text mining, and convolutional networks. This paper presents a novel analytically trained and string kernel using deep neural network, which is tailored for continuous epitope prediction, called: Deep Ridge Regressed Epitope Predictor (DRREP). DRREP was tested on long protein sequences from the following datasets: SARS, Pellequer, HIV, AntiJen, and SEQ194. DRREP was compared to numerous state of the art epitope predictors, including the most recently published predictors called LBtope and DMNLBE. Using area under ROC curve (AUC), DRREP achieved a performance improvement over the best performing predictors on SARS (13.7%), HIV (8.9%), Pellequer (1.5%), and SEQ194 (3.1%), with its performance being matched only on the AntiJen dataset, by the LBtope predictor, where both DRREP and LBtope achieved an AUC of 0.702. DRREP is an analytically trained deep neural network, thus capable of learning in a single step through regression. By combining the features of deep learning, string kernels, and convolutional networks, the system is able to perform residue-by-residue prediction of continues epitopes with higher accuracy than the current state of the art predictors.

  5. KSC-04pd2019

    NASA Image and Video Library

    2004-09-21

    KENNEDY SPACE CENTER, FLA. - KSC Deputy Director Dr. Woodrow Whitlow Jr. signs autographs for students at Gainesville Elementary School, a NASA Explorer School in Gainesville, Ga. Whitlow accompanied Jim Jennings, deputy associate administrator for Institutions and Asset Management at NASA Headquarters, who visited the school to share the new vision for space exploration with the next generation of explorers. Whitlow talked with students about our destiny as explorers, NASA’s stepping stone approach to exploring Earth, the Moon, Mars and beyond, how space impacts our lives, and how people and machines rely on each other in space.

  6. Requirements and Sizing Investigation for the Constellation Space Suit Portable Life Support System Trace Contaminant Control

    NASA Technical Reports Server (NTRS)

    Jennings, Mallory A.; Paul, Heather L.; Waguespack, Glenn M.

    2010-01-01

    This presentation summarized the results of a trade study that evaluated whether trace contaminant control within the Constellation Spacesuit PLSS could be achieved without a Trace Contaminant Control System (TCCS) by relying on suit leakage, ullage loss from the carbon dioxide and humidity control system, and other factors. Mallory Jennings and Dr. Glenn Waguespack studied trace contaminant generation rates to verify that values reflected the latest designs for Constellation spacesuit system pressure garment materials and PLSS hardware. They also calculated TCCS sizing and conducted a literature survey to review the latest developments in trace contaminant technologies.

  7. From the Holocene Thermal Maximum to the Little Ice Age: 11000 years of high resolution marine and terrestrial paleoclimate reconstruction using biomarkers

    NASA Astrophysics Data System (ADS)

    Moossen, H. M.; Abell, R.; Quillmann, U.; Andrews, J. T.; Bendle, J. A.

    2011-12-01

    Holocene climate change is of significantly smaller amplitude than the Pleistocene Glacial-Interglacial cycles, but climatic variations have affected humans over at least the last 4000 years. Studying Holocene climate variations is important to disentangle climate change caused by anthropogenic influences from natural climate change. Sedimentary records stemming from fjords afford the opportunity to study marine and terrestrial paleo-climatic changes and linking the two together. Typically high sediment accumulation rates of fjordic environments facilitate resolution of rapid climate change (RCC) events. The fjords of Northwest Iceland are ideal for studying Holocene climate change as they receive warm water from the Irminger current, but are also influenced by the east Greenland current which brings polar waters to the region (Jennings et al., 2011). In the Holocene, Nordic Seas and the Arctic have been sensitive to climate change. The 8.2 ka event, a cool interval, highlights the sensitivity of that region. Recent climate variations such as the Little Ice Age have been detected in sedimentary records around Iceland (Sicre et al., 2008). We reconstruct Holocene marine and terrestrial climate change producing high resolution (1sample/ 30 years) records from 10700 cal a BP to 300 cal a BP using biomarkers. Alkenones, terrestrial leaf wax components, GDGTs and C/N ratios from a sediment core (MD99-2266) from the mouth of the Ìsafjardardjúp fjord were studied. For more information on the core and evolution of the fjord during the Holocene consult Quillmann et al., (2010) The average chain length (ACL) of terrestrial n-alkanes indicates changes in aridity, and the alkenone unsaturation index represents changes in sea surface temperature. These independent records exhibit similar trends over the studied time period. Our alkenone derived SST record shows the Holocene Thermal Maximum, Holocene Neoglaciation as well as climate change associated with the Medieval Warm

  8. In memory of Eugene (Jenő) von Gothard: a pioneering nineteenth century Hungarian astrophysicist

    NASA Astrophysics Data System (ADS)

    Vincze, Ildikő J.; Jankovics, István

    2012-07-01

    Eugene von Gothard was a Hungarian engineer/scientist, instrument-maker and astrophysicist who founded the Herény Astrophysical Observatory in 1881 and carried out pioneering work in astronomical photography and spectroscopy. In this paper we provide biographical material about von Gothard and describe his observatory, before discussing his astronomical observations and the contribution that hemade to the early development of astrophysics.

  9. Selections from JEN-MIN JIH-PAO, Peiping, on Geology, Exploration, Weather Forecasting, and Cartography.

    DTIC Science & Technology

    1961-03-06

    and area of cultivation land. Otherwise, we cannot keep an accurate account of land and Water, and in the straight - line planning there will be...of production. If we let the masses possess a production direction map and the straight - line planning method, and at the same time formulate them...supplies needed, we not only can use these as the basis for straight - line planning, but we also can list the results attained by straight - line planning

  10. A case of basilar artery aneurysm rupture from 1836: lessons in clinical observation and the natural history of the disease.

    PubMed

    Demetriades, Andreas K; Horiguchi, Takashi; Goodrich, James T; Kawase, Takeshi

    2014-11-01

    Although credit is given to Sir William Gull for highlighting the clinical picture of subarachnoid hemorrhage in 1859, we discuss a case presented by Mr. Egerton A. Jennings, Fellow of the Linnaean Society, published 23 years earlier in the 1836 edition of the Transactions of the Provincial Medical and Surgical Association. This case, probably the first reported in the English language of a basilar aneurysm rupture, is of medico-historical interest. Jennings provided a remarkably accurate and detailed description of the patient, who experienced coma as a result of the severity of subarachnoid hemorrhage. The detailed clinical observations on initial assessment and the description of the patient's deterioration to the time of death are a succinct representation of the natural history of this disease. The author's discussion provides evidence of a philosophy committed to medical education and progress at the time based on principles of rational observation, meticulous clinical acumen, insight into experimental physiology, and the awareness of ethical boundaries. In provincial 1836 England, similar to most of Europe, cerebral localization was elementary. Nonetheless, this case report highlights the attempt at linking structure to function by means of observation on the effects of lesioning. It provides evidence of an established thought process already in progress in England in the 19th century. It is characteristic that this thought process came from a surgical practitioner. The cultivation of practical observation in British surgical culture would allow the late 19th century surgeon scientists to match the contributions of British neurologists with landmark steps in the development and establishment of neurosurgery. Copyright © 2014 Elsevier Inc. All rights reserved.

  11. Seasonal evolution of Titan’s stratosphere near the poles from Cassini/CIRS data

    NASA Astrophysics Data System (ADS)

    Coustenis, Athena; Jennings, Donald E.; Achterberg, Richard K.; Bampasidis, Georgios; Cottini, Valeria; Nixon, Conor A.; Flasar, F. Michael

    2017-10-01

    We report on the monitoring of the seasonal evolution near Titan’s poles. Since 2010, we observe at Titan’s south pole a strong temperature decrease and the onset of a dramatic enhancement of several trace species such as complex hydrocarbons and nitriles (HC3N and C6H6 in particular) previously observed only at high northern latitudes (Coustenis et al. 2016 and references therein). This is due to the transition of Titan’s seasons from northern winter in 2002 to northern summer in 2017 and, at the same time, the advent of winter in the south pole, during which time species with longer chemical lifetimes remain in the north for a little longer undergoing slow photochemical destruction, while those with shorter lifetimes disappear, reappearing in the south. An opposite effect has been expected in the North, but not observed with any significant certainty until 2016. We present here an analysis of nadir spectra acquired by Cassini/CIRS (Jennings et al., 2017) at high resolution in the past years and describe the newly observed decrease in chemical abundances of the components in the North. From 2013 until 2016, the Northern polar region has shown a temperature increase of 10 K, while the South had shown a more significant decrease in a similar period of time. The chemical content in the North is finally showing a clear depletion for most molecules since 2015 (Coustenis et al., 2017).References: Coustenis et al., 2016, Icarus 270, 409-420 ; Coustenis et al., 2017, in preparation; Jennings et al., 2017, Applied Optics 56, no 18, 5274-5294.

  12. A novel Python program for implementation of quality control in the ELISA.

    PubMed

    Wetzel, Hanna N; Cohen, Cinder; Norman, Andrew B; Webster, Rose P

    2017-09-01

    The use of semi-quantitative assays such as the enzyme-linked immunosorbent assay (ELISA) requires stringent quality control of the data. However, such quality control is often lacking in academic settings due to unavailability of software and knowledge. Therefore, our aim was to develop methods to easily implement Levey-Jennings quality control methods. For this purpose, we created a program written in Python (a programming language with an open-source license) and tested it using a training set of ELISA standard curves quantifying the Fab fragment of an anti-cocaine monoclonal antibody in mouse blood. A colorimetric ELISA was developed using a goat anti-human anti-Fab capture method. Mouse blood samples spiked with the Fab fragment were tested against a standard curve of known concentrations of Fab fragment in buffer over a period of 133days stored at 4°C to assess stability of the Fab fragment and to generate a test dataset to assess the program. All standard curves were analyzed using our program to batch process the data and to generate Levey-Jennings control charts and statistics regarding the datasets. The program was able to identify values outside of two standard deviations, and this identification of outliers was consistent with the results of a two-way ANOVA. This program is freely available, which will help laboratories implement quality control methods, thus improving reproducibility within and between labs. We report here successful testing of the program with our training set and development of a method for quantification of the Fab fragment in mouse blood. Copyright © 2017 Elsevier B.V. All rights reserved.

  13. Ultrafast pulse lasers jump to macro applications

    NASA Astrophysics Data System (ADS)

    Griebel, Martin; Lutze, Walter; Scheller, Torsten

    2016-03-01

    Ultrafast Lasers have been proven for several micro applications, e.g. stent cutting, for many years. Within its development of applications Jenoptik has started to use ultrafast lasers in macro applications in the automotive industry. The JenLas D2.fs-lasers with power output control via AOM is an ideal tool for closed loop controlled material processing. Jenoptik enhanced his well established sensor controlled laser weakening process for airbag covers to a new level. The patented process enables new materials using this kind of technology. One of the most sensitive cover materials is genuine leather. As a natural product it is extremely inhomogeneous and sensitive for any type of thermal load. The combination of femtosecond pulse ablation and closed loop control by multiple sensor array opens the door to a new quality level of defined weakening. Due to the fact, that the beam is directed by scanning equipment the process can be split in multiple cycles additionally reducing the local energy input. The development used the 5W model as well as the latest 10W release of JenLas D2.fs and achieved amazing processing speeds which directly fulfilled the requirements of the automotive industry. Having in mind that the average cycle time of automotive processes is about 60s, trials had been done of processing weakening lines in genuine leather of 1.2mm thickness. Parameters had been about 15 cycles with 300mm/s respectively resulting in an average speed of 20mm/s and a cycle time even below 60s. First samples had already given into functional and aging tests and passed successfully.

  14. On the fundamental relation of laser schlieren deflectometry for temperature measurements in filamentary plasmas

    NASA Astrophysics Data System (ADS)

    Schäfer, Jan; Bonaventura, Zdeněk; Foest, Rüdiger

    2015-07-01

    Recently, laser schlieren deflectometry (LSD) had been successfully employed as a temperature measurement method to reveal the heat convection generated by micro filaments of a self-organized non-thermal atmospheric plasma jet. Based on the theory of the temperature measurements using LSD, in this work, three approaches for an application of the method are introduced: (i) a hyperbolic-like model of refractive index is applied which allows an analytical theory for the evaluation of the deflection angle to be developed, (ii) a Gaussian shape model for the filament temperature is implemented which is analyzed numerically and (iii) an experimental calibration of the laser deflection with a gas mixture of helium and argon is performed. Thus, these approaches demonstrate that a universal relation between the relative maximum temperature of the filament core (T1/T0) and a the maximum deflection angle δ1 of the laser beam can be written as T1/T0=(1 - δ1/δ0)-1, where δ0 is a parameter that is defined by the configuration of the experiment and by the assumed model for the shape of the temperature profile. Contribution to the topical issue "The 14th International Symposium on High Pressure Low Temperature Plasma Chemistry (HAKONE XIV)", edited by Nicolas Gherardi, Ronny Brandenburg and Lars Stollenwark

  15. KSC-04PD-0263

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. NASA and government officials are gathered to hear about the assets of the Central Florida Research Park, near Orlando, as the site of NASAs new Shared Services Center. Seated at right are Lisa Malone, director of KSC External Affairs, and Joel Wells, with the Government Relations Office. Fourth from right is Jim Jennings, NASA deputy associate administrator for institutions and asset management. Six sites around the U.S. are under consideration for the center, which would centralize NASAs payroll, accounting, human resources, facilities and procurement offices that are now handled at each field center. The consolidation is part of the One NASA focus.

  16. Biogeochemistry of Framvaren, A permanently Anoxic Fjord

    NASA Astrophysics Data System (ADS)

    Millero, Frank J.

    Recently (May 28-30, 1986), a workshop was held in Farsund, Norway, to discuss the biogeochemistry of an anoxic fjord called Framvaren. In the last 7 years a group of marine scientists from Norway, Sweden, Canada, and the United States has been studying this fjord. The workshop was held to discuss the recent findings of this international effort. A new expedition is planned in February 1987 (provided that the ice is thick enough) and in June 1988. Marine chemists, microbiologists, or geologists interested in participating in this study should contact Jens Skei (Norwegian Institute of Water Research, PB Box 333, Blindern, Oslo 3, Norway), who is coordinating the investigations.

  17. Experiments on the Filtration of Solution of Sodium Uranate with Nitric Acid; ENSAYOS DE FILTRACION DE SOLUCIONES DE DISOLUCION DE URANATO SODICO CON ACIDO NITRICO

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Clement, J.M.; Luina, A.P.; Jodra, L.G.

    1957-01-01

    In the recovery of uraniuma from leach solutions, the pilot plant of the J.E.N, does not clarify the solution and the sodium uranate carries with it a high proportion of impurities. Therefore, a study was made to determine the optimum conditions for the filtration of sodium uranate from nitric acid solution and to establish modifications in the dissolution processes at present in use for the concentrates. The effects of pressure, addition of CaSO/sub 4/ and Kieselgur, pH, and temperature were investigated The modifications made to the pilot plant as a result of these studies are briefly described. (J.S.R.)

  18. KSC-01pp1575

    NASA Image and Video Library

    2001-09-27

    KENNEDY SPACE CENTER, Fla. -- Maria Lopez-Tellado (center) and Rey N. Diaz (right) display the plaques they received at the annual Hispanic Heritage Month Celebration, held at the Kurt Debus Conference Facility at KSC. The two were recognized for their efforts as chairs of the event, which featuraed a luncheon and comments by Deputy Center Director Jim Jennings and Miguel Rodriquez, chief, Integration Office, of the Joint Performance Management Office. Joseph Tellado (left), International Space Station/Payload Processing, led the pledge of allegiance and invocation. The Merrit Island High School ROTC provided the color guard. The event was sponsored by the Hispanic Employment Program Working Group at KSC

  19. KSC-2010-4578

    NASA Image and Video Library

    2010-09-05

    ORLANDO, Fla. -- During the 2010 Tom Joyner Family Reunion, space activist and actress Nichelle Nichols talks to attendees at the Gaylord Palms Convention Center in Orlando, Fla. To encourage student attendees to focus on pursuing careers in science, technology, engineering and mathematics (STEM), NASA featured some of its greatest legends and trailblazers during a panel discussion at the reunion event. Other panel members included NASA astronaut Leland Melvin, Christine Darden, Lew Braxton, Robyn Gordon and Jim Jennings. NASA's Education Office sponsored the panel discussion and educational activities as part of the agency's "Summer of Innovation" initiative and the federal "Educate to Innovate" campaign. Photo credit: NASA/Amanda Diller

  20. KSC-2010-4577

    NASA Image and Video Library

    2010-09-05

    ORLANDO, Fla. -- During the 2010 Tom Joyner Family Reunion, NASA astronaut Leland Melvin talks to attendees at the Gaylord Palms Convention Center in Orlando, Fla. To encourage student attendees to focus on pursuing careers in science, technology, engineering and mathematics (STEM), NASA featured some of its greatest legends and trailblazers during a panel discussion at the reunion event. Panel members, sitting from left, are Christine Darden, Lew Braxton, Robyn Gordon, Jim Jennings, and space activist and actress Nichelle Nichols. NASA's Education Office sponsored the panel discussion and educational activities as part of the agency's "Summer of Innovation" initiative and the federal "Educate to Innovate" campaign. Photo credit: NASA/Amanda Diller

  1. Upon Further Review: V. An Examination of Previous Lightcurve Analysis from the Palmer Divide Observatory

    NASA Astrophysics Data System (ADS)

    Warner, Brian D.

    2011-01-01

    Updated results are given for nine asteroids previously reported from the Palmer Divide Observatory (PDO). The original images were re-measured to obtain new data sets using the latest version of MPO Canopus photometry software, analysis tools, and revised techniques for linking multiple observing runs covering several days to several weeks. Results that were previously not reported or were moderately different were found for 1659 Punkajarju, 1719 Jens, 1987 Kaplan, 2105 Gudy, 2961 Katsurahama, 3285 Ruth Wolfe, 3447 Burckhalter, 7816 Hanoi, and (34817) 2000 SE116. This is one in a series of papers that will examine results obtained during the initial years of the asteroid lightcurve program at PDO.

  2. [Selecting methods of controls concentration for internal quality control and continuity of control chart between different reagent lots for HBsAg qualitative detection].

    PubMed

    Li, Jin-ming; Zheng, Huai-jing; Wang, Lu-nan; Deng, Wei

    2003-04-01

    To establish a model for one choosing controls with a suitable concentration for internal quality control (IQC) with qualitative ELISA detection, and a consecutive plotting method on Levey-Jennings control chart when reagent kit lot is changed. First, a series of control serum with 0.2, 0.5, 1.0, 2.0 and 5.0ng/ml HBsAg respectively were assessed for within-run and between-run precision according to NCCLs EP5 document. Then, a linear regression equation (y=bx + a) with best correlation coefficient (r > 0.99) was established based on S/CO values of the series of control serum. Finally, one could choose controls with S/CO value calculated from the equation (y = bx + a) minus the product of the S/CO value multiplying three-fold between-run CV to be still more than 1.0 for IQC use. For consecutive plotting on Levey-Jennings control chart when ELISA kit lot was changed, the new lot kits were used to detect the same series of HBsAg control serum as above. Then, a new linear regression equation (y2 = b2x2 + a2) with best correlation coefficient was obtained. The old one (y1 =b1x1 + a1) could be obtained based on the mean values from above precision assessment. The S/CO value of a control serum detected by new lot kit could be changed to that detected by old kit lot based on the factor of y2/y1. Therefore, the plotting on primary Levey-Jennings control chart could be continued. The within-run coefficient of variation CV of the ELISA method for control serum with 0.2, 0.5, 1.0, 2.0 and 5.0ng/ml HBsAg were 11.08%, 9.49%, 9.83%, 9.18% and 7.25%, respectively, and between-run CV were 13.25%, 14.03%, 15.11%, 13.29% and 9.92%. The linear regression equation with best correlation coefficient from a test at random was y = 3.509x + 0.180. The suitable concentration of control serum for IQC could be 0.5ng/ml or 1.0ng/ml. The linear regression equation from the old lot and other two new lots of the ELISA kits were y1 = 3.550(x1) + 0.226, y2 = 3.238(x2) +0.388, and y3 =3.428(x3) + 0

  3. AgeFactDB--the JenAge Ageing Factor Database--towards data integration in ageing research.

    PubMed

    Hühne, Rolf; Thalheim, Torsten; Sühnel, Jürgen

    2014-01-01

    AgeFactDB (http://agefactdb.jenage.de) is a database aimed at the collection and integration of ageing phenotype data including lifespan information. Ageing factors are considered to be genes, chemical compounds or other factors such as dietary restriction, whose action results in a changed lifespan or another ageing phenotype. Any information related to the effects of ageing factors is called an observation and is presented on observation pages. To provide concise access to the complete information for a particular ageing factor, corresponding observations are also summarized on ageing factor pages. In a first step, ageing-related data were primarily taken from existing databases such as the Ageing Gene Database--GenAge, the Lifespan Observations Database and the Dietary Restriction Gene Database--GenDR. In addition, we have started to include new ageing-related information. Based on homology data taken from the HomoloGene Database, AgeFactDB also provides observation and ageing factor pages of genes that are homologous to known ageing-related genes. These homologues are considered as candidate or putative ageing-related genes. AgeFactDB offers a variety of search and browse options, and also allows the download of ageing factor or observation lists in TSV, CSV and XML formats.

  4. AgeFactDB—the JenAge Ageing Factor Database—towards data integration in ageing research

    PubMed Central

    Hühne, Rolf; Thalheim, Torsten; Sühnel, Jürgen

    2014-01-01

    AgeFactDB (http://agefactdb.jenage.de) is a database aimed at the collection and integration of ageing phenotype data including lifespan information. Ageing factors are considered to be genes, chemical compounds or other factors such as dietary restriction, whose action results in a changed lifespan or another ageing phenotype. Any information related to the effects of ageing factors is called an observation and is presented on observation pages. To provide concise access to the complete information for a particular ageing factor, corresponding observations are also summarized on ageing factor pages. In a first step, ageing-related data were primarily taken from existing databases such as the Ageing Gene Database—GenAge, the Lifespan Observations Database and the Dietary Restriction Gene Database—GenDR. In addition, we have started to include new ageing-related information. Based on homology data taken from the HomoloGene Database, AgeFactDB also provides observation and ageing factor pages of genes that are homologous to known ageing-related genes. These homologues are considered as candidate or putative ageing-related genes. AgeFactDB offers a variety of search and browse options, and also allows the download of ageing factor or observation lists in TSV, CSV and XML formats. PMID:24217911

  5. Susan Parker Bodine, Letter to Brian Jennings of American Coalition for Ethanol, November 7, 2006

    EPA Pesticide Factsheets

    This letter responds to correspondence concerning the applicability of EPA's Facility Response Plan (FRP) regulations to ethanol production and storage facilities and whether denatured ethanol is an oil.

  6. What Does Titan's Atmosphere Look Like Near The Poles At The End Of The Cassini Mission ?

    NASA Astrophysics Data System (ADS)

    Nixon, C. A.; Coustenis, A.; Jennings, D. E.; Achterberg, R. K.; Bampasidis, G.; Cottini, V.; Flasar, F. M.; Lavvas, P.

    2017-12-01

    The Cassini mission ends on Sept. 15, 2017, after - among other - 127 targeted Titan flybys. We have monitored the seasonal evolution near Titan's poles during the mission. Titan's North pole had been enhanced in chemical species since the beginning of the observations, but since 2010, we observe at Titan's south pole a strong temperature decrease and the onset of a dramatic enhancement of several trace species such as complex hydrocarbons and nitriles (HC3N and C6H6 in particular) previously observed only at high northern latitudes (Coustenis et al. 2016 and references therein). This is due to the transition of Titan's seasons from northern winter in 2002 to northern summer in 2017 and, at the same time, the advent of winter in the south pole, during which time species with longer chemical lifetimes remain in the north for a little longer undergoing slow photochemical destruction, while those with shorter lifetimes disappear, reappearing in the south. An opposite effect has been expected in the North, but not observed with any significant certainty until 2016. We present here an analysis of nadir spectra acquired by Cassini/CIRS (Jennings et al., 2017) at high resolution in the past years and describe the newly observed decrease in chemical abundances of the components in the North. From 2013 until 2016, the Northern polar region has shown a temperature increase of 10 K, while the South had shown a more significant decrease in a similar period of time. The chemical content in the North is finally showing a clear depletion for most molecules since 2015 (Coustenis et al., 2017). References: Coustenis et al., 2016, Icarus 270, 409-420 ; Coustenis et al., 2017, submitted; Jennings et al., 2017, Applied Optics 56, no 18, 5274-5294.

  7. Titan's Surface Temperatures Maps from Cassini - CIRS Observations

    NASA Astrophysics Data System (ADS)

    Cottini, Valeria; Nixon, C. A.; Jennings, D. E.; Anderson, C. M.; Samuelson, R. E.; Irwin, P. G. J.; Flasar, F. M.

    2009-09-01

    The Cassini Composite Infrared Spectrometer (CIRS) observations of Saturn's largest moon, Titan, are providing us with the ability to detect the surface temperature of the planet by studying its outgoing radiance through a spectral window in the thermal infrared at 19 μm (530 cm-1) characterized by low opacity. Since the first acquisitions of CIRS Titan data the instrument has gathered a large amount of spectra covering a wide range of latitudes, longitudes and local times. We retrieve the surface temperature and the atmospheric temperature profile by modeling proper zonally averaged spectra of nadir observations with radiative transfer computations. Our forward model uses the correlated-k approximation for spectral opacity to calculate the emitted radiance, including contributions from collision induced pairs of CH4, N2 and H2, haze, and gaseous emission lines (Irwin et al. 2008). The retrieval method uses a non-linear least-squares optimal estimation technique to iteratively adjust the model parameters to achieve a spectral fit (Rodgers 2000). We show an accurate selection of the wide amount of data available in terms of footprint diameter on the planet and observational conditions, together with the retrieved results. Our results represent formal retrievals of surface brightness temperatures from the Cassini CIRS dataset using a full radiative transfer treatment, and we compare to the earlier findings of Jennings et al. (2009). In future, application of our methodology over wide areas should greatly increase the planet coverage and accuracy of our knowledge of Titan's surface brightness temperature. References: Irwin, P.G.J., et al.: "The NEMESIS planetary atmosphere radiative transfer and retrieval tool" (2008). JQSRT, Vol. 109, pp. 1136-1150, 2008. Rodgers, C. D.: "Inverse Methods For Atmospheric Sounding: Theory and Practice". World Scientific, Singapore, 2000. Jennings, D.E., et al.: "Titan's Surface Brightness Temperatures." Ap. J. L., Vol. 691, pp. L103-L

  8. Transport and cytotoxicity of the anticancer drug 3-bromopyruvate in the yeast Saccharomyces cerevisiae.

    PubMed

    Lis, Paweł; Zarzycki, Marek; Ko, Young H; Casal, Margarida; Pedersen, Peter L; Goffeau, Andre; Ułaszewski, Stanisław

    2012-02-01

    We have investigated the cytotoxicity in Saccharomyces cerevisiae of the novel antitumor agent 3-bromopyruvate (3-BP). 3-BP enters the yeast cells through the lactate/pyruvate H(+) symporter Jen1p and inhibits cell growth at minimal inhibitory concentration of 1.8 mM when grown on non-glucose conditions. It is not submitted to the efflux pumps conferring Pleiotropic Drug Resistance in yeast. Yeast growth is more sensitive to 3-BP than Gleevec (Imatinib methanesulfonate) which in contrast to 3-BP is submitted to the PDR network of efflux pumps. The sensitivity of yeast to 3-BP is increased considerably by mutations or chemical treatment by buthionine sulfoximine that decrease the intracellular concentration of glutathione.

  9. Remarks on non-maximal integral elements of the Cartan plane in jet spaces

    NASA Astrophysics Data System (ADS)

    Bächtold, M.; Moreno, G.

    2014-11-01

    There is a natural filtration on the space of degree-k homogeneous polynomials in n independent variables with coefficients in the algebra of smooth functions on the Grassmannian Gr (n,s), determined by the tautological bundle. In this paper we show that the space of s-dimensional integral elements of a Cartan plane on J(E,n), with dimE=n+m, has an affine bundle structure modeled by the so-obtained bundles over Gr (n,s), and we study a natural distribution associated with it. As an example, we show that a third-order nonlinear PDE of Monge-Ampère type is not contact-equivalent to a quasi-linear one.

  10. KSC-03pd0296

    NASA Image and Video Library

    2003-02-07

    KENNEDY SPACE CENTER, FLA. - A Columbia Crew Memorial Service is held at the Shuttle Landing Facility for KSC employees and invited guests. NASA Associate Deputy Administrator for Institutions and Asset Management James L. Jennings is at the podium. The Columbia and her crew of seven were lost on Feb. 1, 2003, over East Texas as they returned to Earth after a 16-day research mission. Taking part in the service were NASA Administrator Sean O’Keefe, former KSC Director Robert Crippen, astronaut Jim Halsell, several employees, area clergymen, and members of Patrick Air Force Base. The service concluded with a “Missing Man Formation Fly Over” by NASA T-38 jet aircraft.

  11. KSC-04PD-2015

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. Astronaut Leland Melvin talks to students in the cafeteria at Gainesville Elementary School, a NASA Explorer School in Gainesville, Ga. Melvin joined Jim Jennings, deputy associate administrator for Institutions and Asset Management at NASA Headquarters, on the visit to the school to share the new vision for space exploration with the next generation of explorers. Melvin talked about the importance of teamwork and what it takes for mission success. Also visiting was KSC Deputy Director Woodrow Whitlow Jr., who talked with students about our destiny as explorers, NASAs stepping stone approach to exploring Earth, the Moon, Mars and beyond, how space impacts our lives, and how people and machines rely on each other in space.

  12. KSC-04PD-1127

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. -- A KSC employee asks a question of the panel conducting the Culture Change Process All Hands Meeting in the Training Auditorium. The purpose of the meeting was for employees to gain further insight into the Agencys Vision for Space Exploration and the direction cultural change will take at KSC in order to assume its role within this vision. Panel members included James W. Kennedy, KSC director; Jim Jennings, Deputy Associate Administrator for Institutions and Asset Management; Lynn Cline, Deputy Associate Administrator for Space Flight; Bob Sieck, former Director of Space Shuttle Processing at KSC; and Jim Wetherbee, astronaut and Technical Assistant to the Director of Safety and Mission Assurance at the Johnson Space Center.

  13. KSC-04PD-2018

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. Astronaut Leland Melvin signs autographs for students at Gainesville Elementary School, a NASA Explorer School in Gainesville, Ga. Melvin joined Jim Jennings, deputy associate administrator for Institutions and Asset Management at NASA Headquarters, on the visit to the school to share the new vision for space exploration with the next generation of explorers. Melvin talked about the importance of teamwork and what it takes for mission success. Also visiting was KSC Deputy Director Woodrow Whitlow Jr., who talked with students about our destiny as explorers, NASAs stepping stone approach to exploring Earth, the Moon, Mars and beyond, how space impacts our lives, and how people and machines rely on each other in space.

  14. KSC-04PD-2014

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. Astronaut Leland Melvin joins students in the cafeteria at Gainesville Elementary School, a NASA Explorer School in Gainesville, Ga. Melvin joined Jim Jennings, deputy associate administrator for Institutions and Asset Management at NASA Headquarters, on the visit to the school to share the new vision for space exploration with the next generation of explorers. Melvin talked about the importance of teamwork and what it takes for mission success. Also visiting was KSC Deputy Director Woodrow Whitlow Jr., who talked with students about our destiny as explorers, NASAs stepping stone approach to exploring Earth, the Moon, Mars and beyond, how space impacts our lives, and how people and machines rely on each other in space.

  15. Displacement current phenomena in the magnetically insulated transmission lines of the refurbished Z accelerator

    NASA Astrophysics Data System (ADS)

    McBride, R. D.; Jennings, C. A.; Vesey, R. A.; Rochau, G. A.; Savage, M. E.; Stygar, W. A.; Cuneo, M. E.; Sinars, D. B.; Jones, M.; Lechien, K. R.; Lopez, M. R.; Moore, J. K.; Struve, K. W.; Wagoner, T. C.; Waisman, E. M.

    2010-12-01

    Experimental data is presented that illustrates important displacement current phenomena in the magnetically insulated transmission lines (MITLs) of the refurbished Z accelerator [D. V. Rose , Phys. Rev. ST Accel. Beams 13, 010402 (2010)PRABFM1098-440210.1103/PhysRevSTAB.13.010402]. Specifically, we show how displacement current in the MITLs causes significant differences between the accelerator current measured at the vacuum-insulator stack (at a radial position of about 1.6 m from the Z axis of symmetry) and the accelerator current measured at the load (at a radial position of about 6 cm from the Z axis of symmetry). The importance of accounting for these differences was first emphasized by Jennings et al. [C. A. Jennings , IEEE Trans. Plasma Sci. 38, 529 (2010)ITPSBD0093-381310.1109/TPS.2010.2042971], who calculated them using a full transmission-line-equivalent model of the four-level MITL system. However, in the data presented by Jennings et al., many of the interesting displacement current phenomena were obscured by parasitic current losses that occurred between the vacuum-insulator stack and the load (e.g., electron flow across the anode-cathode gap). By contrast, the data presented herein contain very little parasitic current loss, and thus for these low-loss experiments we are able to demonstrate that the differences between the current measured at the stack and the current measured at the load are due primarily to the displacement current that results from the shunt capacitance of the MITLs (about 8.41 nF total). Demonstrating this is important because displacement current is an energy storage mechanism, where energy is stored in the MITL electric fields and can later be used by the system. Thus, even for higher-loss experiments, the differences between the current measured at the stack and the current measured at the load are often largely due to energy storage and subsequent release, as opposed to being due solely to some combination of measurement

  16. KSC-03PD-3139

    NASA Technical Reports Server (NTRS)

    2003-01-01

    KENNEDY SPACE CENTER, FLA. The Honorable Toni Jennings, lieutenant governor of the state of Florida, speaks at a dedication and ribbon-cutting ceremony for the Space Life Sciences Lab hosted by NASA-Kennedy Space Center and the state of Florida at the new lab. Completed in August, the facility encompasses more than 100,000 square feet and was formerly known as the Space Experiment Research and Processing Laboratory or SERPL. The state, through the Florida Space Authority, built the research lab which is host to NASA, NASAs Life Sciences Services contractor Dynamac Corp., Bionetics Corp., and researchers from the University of Florida. Dynamac Corp. leases the facility. The Florida Space Research Institute is responsible for gaining additional tenants from outside the NASA community.

  17. KSC-04pd1118

    NASA Image and Video Library

    2004-05-10

    KENNEDY SPACE CENTER, FLA. -- Bob Sieck, former Director of Space Shuttle Processing at KSC addresses KSC employees assembled in the Training Auditorium for a Culture Change Process All Hands Meeting. The purpose of the meeting was for employees to gain further insight into the Agency’s Vision for Space Exploration and the direction cultural change will take at KSC in order to assume its role within this vision. Other participants included James W. Kennedy, KSC director; Jim Jennings, Deputy Associate Administrator for Institutions and Asset Management; Lynn Cline, Deputy Associate Administrator for Space Flight; and Jim Wetherbee, astronaut and Technical Assistant to the Director of Safety and Mission Assurance at Johnson Space Center. Following their remarks, members of the panel entertained questions and comments from the audience.

  18. KSC-04pd1120

    NASA Image and Video Library

    2004-05-10

    KENNEDY SPACE CENTER, FLA. -- Jim Wetherbee, astronaut and Technical Assistant to the Director of Safety and Mission Assurance at Johnson Space Center addresses KSC employees assembled in the Training Auditorium for a Culture Change Process All Hands Meeting. The purpose of the meeting was for employees to gain further insight into the Agency’s Vision for Space Exploration and the direction cultural change will take at KSC in order to assume its role within this vision. Other participants included James W. Kennedy, KSC director; Jim Jennings, Deputy Associate Administrator for Institutions and Asset Management; Lynn Cline, Deputy Associate Administrator for Space Flight; and Bob Sieck, former Director of Space Shuttle Processing at KSC. Following their remarks, members of the panel entertained questions and comments from the audience.

  19. KSC-04pd1115

    NASA Image and Video Library

    2004-05-10

    KENNEDY SPACE CENTER, FLA. -- Jim Jennings, Deputy Associate Administrator for Institutions and Asset Management addresses KSC employees assembled in the Training Auditorium for a Culture Change Process All Hands Meeting. The purpose of the meeting was for employees to gain further insight into the Agency’s Vision for Space Exploration and the direction cultural change will take at KSC in order to assume its role within this vision. Other participants included James W. Kennedy, KSC director; Lynn Cline, Deputy Associate Administrator for Space Flight; Bob Sieck, former Director of Space Shuttle Processing at KSC; and Jim Wetherbee, astronaut and Technical Assistant to the Director of Safety and Mission Assurance at Johnson Space Center. Following their remarks, members of the panel entertained questions and comments from the audience.

  20. KSC-04pd1119

    NASA Image and Video Library

    2004-05-10

    KENNEDY SPACE CENTER, FLA. -- Jim Wetherbee, astronaut and Technical Assistant to the Director of Safety and Mission Assurance at Johnson Space Center addresses KSC employees assembled in the Training Auditorium for a Culture Change Process All Hands Meeting. The purpose of the meeting was for employees to gain further insight into the Agency’s Vision for Space Exploration and the direction cultural change will take at KSC in order to assume its role within this vision. Other participants included James W. Kennedy, KSC director; Jim Jennings, Deputy Associate Administrator for Institutions and Asset Management; Lynn Cline, Deputy Associate Administrator for Space Flight; and Bob Sieck, former Director of Space Shuttle Processing at KSC. Following their remarks, members of the panel entertained questions and comments from the audience.

  1. KSC-04pd1122

    NASA Image and Video Library

    2004-05-10

    KENNEDY SPACE CENTER, FLA. -- The panel members participating in the Culture Change Process All Hands Meeting entertain questions and comments from the audience assembled in the Training Auditorium. From left, they are James W. Kennedy, KSC director; Jim Jennings, Deputy Associate Administrator for Institutions and Asset Management; Lynn Cline, Deputy Associate Administrator for Space Flight; Bob Sieck, former Director of Space Shuttle Processing at KSC; and Jim Wetherbee, astronaut and Technical Assistant to the Director of Safety and Mission Assurance at Johnson Space Center. The purpose of the meeting was for employees to gain further insight into the Agency’s Vision for Space Exploration and the direction cultural change will take at KSC in order to assume its role within this vision.

  2. KSC-04pd1113

    NASA Image and Video Library

    2004-05-10

    KENNEDY SPACE CENTER, FLA. -- KSC employees assemble in the Training Auditorium for a Culture Change Process All Hands Meeting. The purpose of the meeting was for employees to gain further insight into the Agency’s Vision for Space Exploration and the direction cultural change will take at KSC in order to assume its role within this vision. Panel members included James W. Kennedy, KSC director; Jim Jennings, Deputy Associate Administrator for Institutions and Asset Management; Lynn Cline, Deputy Associate Administrator for Space Flight; Bob Sieck, former Director of Space Shuttle Processing at KSC; and Jim Wetherbee, astronaut and Technical Assistant to the Director of Safety and Mission Assurance at the Johnson Space Center. Following their remarks, members of the panel entertained questions and comments from the audience.

  3. KSC-04pd1114

    NASA Image and Video Library

    2004-05-10

    KENNEDY SPACE CENTER, FLA. -- Jim Jennings, Deputy Associate Administrator for Institutions and Asset Management addresses KSC employees assembled in the Training Auditorium for a Culture Change Process All Hands Meeting. The purpose of the meeting was for employees to gain further insight into the Agency’s Vision for Space Exploration and the direction cultural change will take at KSC in order to assume its role within this vision. Other participants included James W. Kennedy, KSC director; Lynn Cline, Deputy Associate Administrator for Space Flight; Bob Sieck, former Director of Space Shuttle Processing at KSC; and Jim Wetherbee, astronaut and Technical Assistant to the Director of Safety and Mission Assurance at Johnson Space Center. Following their remarks, members of the panel entertained questions and comments from the audience.

  4. KSC-04pd1112

    NASA Image and Video Library

    2004-05-10

    KENNEDY SPACE CENTER, FLA. -- KSC employees assemble in the Training Auditorium for a Culture Change Process All Hands Meeting. The purpose of the meeting was for employees to gain further insight into the Agency’s Vision for Space Exploration and the direction cultural change will take at KSC in order to assume its role within this vision. Panel members included James W. Kennedy, KSC director; Jim Jennings, Deputy Associate Administrator for Institutions and Asset Management; Lynn Cline, Deputy Associate Administrator for Space Flight; Bob Sieck, former Director of Space Shuttle Processing at KSC; and Jim Wetherbee, astronaut and Technical Assistant to the Director of Safety and Mission Assurance at the Johnson Space Center. Following their remarks, members of the panel entertained questions and comments from the audience.

  5. KSC-04pd1117

    NASA Image and Video Library

    2004-05-10

    KENNEDY SPACE CENTER, FLA. -- Bob Sieck, former Director of Space Shuttle Processing at KSC addresses KSC employees assembled in the Training Auditorium for a Culture Change Process All Hands Meeting. The purpose of the meeting was for employees to gain further insight into the Agency’s Vision for Space Exploration and the direction cultural change will take at KSC in order to assume its role within this vision. Other participants included James W. Kennedy, KSC director; Jim Jennings, Deputy Associate Administrator for Institutions and Asset Management; Lynn Cline, Deputy Associate Administrator for Space Flight; and Jim Wetherbee, astronaut and Technical Assistant to the Director of Safety and Mission Assurance at Johnson Space Center. Following their remarks, members of the panel entertained questions and comments from the audience.

  6. KSC-04pd1121

    NASA Image and Video Library

    2004-05-10

    KENNEDY SPACE CENTER, FLA. -- The panel members participating in the Culture Change Process All Hands Meeting entertain questions and comments from the audience assembled in the Training Auditorium. From left, they are James W. Kennedy, KSC director; Jim Jennings, Deputy Associate Administrator for Institutions and Asset Management; Lynn Cline, Deputy Associate Administrator for Space Flight; Bob Sieck, former Director of Space Shuttle Processing at KSC; and Jim Wetherbee, astronaut and Technical Assistant to the Director of Safety and Mission Assurance at Johnson Space Center. The purpose of the meeting was for employees to gain further insight into the Agency’s Vision for Space Exploration and the direction cultural change will take at KSC in order to assume its role within this vision.

  7. KSC-04pd1110

    NASA Image and Video Library

    2004-05-10

    KENNEDY SPACE CENTER, FLA. -- Center Director James W. Kennedy addresses KSC employees assembled in the Training Auditorium for a Culture Change Process All Hands Meeting. The purpose of the meeting was for employees to gain further insight into the Agency’s Vision for Space Exploration and the direction cultural change will take at KSC in order to assume its role within this vision. Other participants included Jim Jennings, Deputy Associate Administrator for Institutions and Asset Management; Lynn Cline, Deputy Associate Administrator for Space Flight; Bob Sieck, former Director of Space Shuttle Processing at KSC; and Jim Wetherbee, astronaut and Technical Assistant to the Director of Safety and Mission Assurance at Johnson Space Center. Following their remarks, members of the panel entertained questions and comments from the audience.

  8. KSC-04pd1111

    NASA Image and Video Library

    2004-05-10

    KENNEDY SPACE CENTER, FLA. -- Center Director James W. Kennedy addresses KSC employees assembled in the Training Auditorium for a Culture Change Process All Hands Meeting. The purpose of the meeting was for employees to gain further insight into the Agency’s Vision for Space Exploration and the direction cultural change will take at KSC in order to assume its role within this vision. Other participants included Jim Jennings, Deputy Associate Administrator for Institutions and Asset Management; Lynn Cline, Deputy Associate Administrator for Space Flight; Bob Sieck, former Director of Space Shuttle Processing at KSC; and Jim Wetherbee, astronaut and Technical Assistant to the Director of Safety and Mission Assurance at Johnson Space Center. Following their remarks, members of the panel entertained questions and comments from the audience.

  9. KSC-04pd1116

    NASA Image and Video Library

    2004-05-10

    KENNEDY SPACE CENTER, FLA. -- Lynn Cline, Deputy Associate Administrator for Space Flight addresses KSC employees assembled in the Training Auditorium for a Culture Change Process All Hands Meeting. The purpose of the meeting was for employees to gain further insight into the Agency’s Vision for Space Exploration and the direction cultural change will take at KSC in order to assume its role within this vision. Other participants included James W. Kennedy, KSC director; Jim Jennings, Deputy Associate Administrator for Institutions and Asset Management; Bob Sieck, former Director of Space Shuttle Processing at KSC; and Jim Wetherbee, astronaut and Technical Assistant to the Director of Safety and Mission Assurance at Johnson Space Center. Following their remarks, members of the panel entertained questions and comments from the audience.

  10. Bufo canorus Camp 1916, Yosemite Toad.

    USGS Publications Warehouse

    Davidson, Carlos; Fellers, Gary M.; Lannoo, Michael

    2005-01-01

    Yosemite toads (Bufo canorus) are endemic to the Sierra Nevada, California, from Ebbetts Pass, Alpine County to the Spanish Mountain area, Fresno County (Karlstrom 1962, 1973; Stebbins 1966; unpublished Sierra National Forest survey data, 1995, 2002). Sites occur from 1,950–3,444 m elevation, with the majority of sites between 2,590–3,048 m (Karlstrom, 1962). Jennings and Hayes (1994a) estimate that populations have disappeared from 50% of historically reported sites, although the overall range of the species may have only contracted in the far north and in western Fresno County. Disappearances have been concentrated at lower elevation sites on the western edge of the range, with greater persistence at higher elevation sites (Davidson et al., 2002).

  11. KSC-04PD-2009

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. KSC Deputy Director Dr. Woodrow Whitlow Jr. (far right) asks students questions at Gainesville Elementary School, a NASA Explorer School in Gainesville, Ga. Whitlow and astronaut Leland Melvin (center) accompanied Jim Jennings (at left), deputy associate administrator for Institutions and Asset Management at NASA Headquarters, on the visit to the school to share the new vision for space exploration with the next generation of explorers. Whitlow talked with students about our destiny as explorers, NASAs stepping stone approach to exploring Earth, the Moon, Mars and beyond, how space impacts our lives, and how people and machines rely on each other in space. Melvin talked about the importance of teamwork and what it takes for mission success.

  12. KSC-04PD-1118

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. -- Bob Sieck, former Director of Space Shuttle Processing at KSC addresses KSC employees assembled in the Training Auditorium for a Culture Change Process All Hands Meeting. The purpose of the meeting was for employees to gain further insight into the Agencys Vision for Space Exploration and the direction cultural change will take at KSC in order to assume its role within this vision. Other participants included James W. Kennedy, KSC director; Jim Jennings, Deputy Associate Administrator for Institutions and Asset Management; Lynn Cline, Deputy Associate Administrator for Space Flight; and Jim Wetherbee, astronaut and Technical Assistant to the Director of Safety and Mission Assurance at Johnson Space Center. Following their remarks, members of the panel entertained questions and comments from the audience.

  13. KSC-04PD-1126

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. -- Jim Jennings (left), Deputy Associate Administrator for Institutions and Asset Management, looks on as Lynn Cline, Deputy Associate Administrator for Space Flight, responds to a question asked by a member of the audience attending the Culture Change Process All Hands Meeting in the Training Auditorium. The purpose of the meeting was for employees to gain further insight into the Agencys Vision for Space Exploration and the direction cultural change will take at KSC in order to assume its role within this vision. Other panel members were James W. Kennedy, KSC director; Bob Sieck, former Director of Space Shuttle Processing at KSC; and Jim Wetherbee, astronaut and Technical Assistant to the Director of Safety and Mission Assurance at Johnson Space Center.

  14. KSC-04PD-1117

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. -- Bob Sieck, former Director of Space Shuttle Processing at KSC addresses KSC employees assembled in the Training Auditorium for a Culture Change Process All Hands Meeting. The purpose of the meeting was for employees to gain further insight into the Agencys Vision for Space Exploration and the direction cultural change will take at KSC in order to assume its role within this vision. Other participants included James W. Kennedy, KSC director; Jim Jennings, Deputy Associate Administrator for Institutions and Asset Management; Lynn Cline, Deputy Associate Administrator for Space Flight; and Jim Wetherbee, astronaut and Technical Assistant to the Director of Safety and Mission Assurance at Johnson Space Center. Following their remarks, members of the panel entertained questions and comments from the audience.

  15. KSC-04PD-1112

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. -- KSC employees assemble in the Training Auditorium for a Culture Change Process All Hands Meeting. The purpose of the meeting was for employees to gain further insight into the Agencys Vision for Space Exploration and the direction cultural change will take at KSC in order to assume its role within this vision. Panel members included James W. Kennedy, KSC director; Jim Jennings, Deputy Associate Administrator for Institutions and Asset Management; Lynn Cline, Deputy Associate Administrator for Space Flight; Bob Sieck, former Director of Space Shuttle Processing at KSC; and Jim Wetherbee, astronaut and Technical Assistant to the Director of Safety and Mission Assurance at the Johnson Space Center. Following their remarks, members of the panel entertained questions and comments from the audience.

  16. KSC-04PD-1111

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. -- Center Director James W. Kennedy addresses KSC employees assembled in the Training Auditorium for a Culture Change Process All Hands Meeting. The purpose of the meeting was for employees to gain further insight into the Agencys Vision for Space Exploration and the direction cultural change will take at KSC in order to assume its role within this vision. Other participants included Jim Jennings, Deputy Associate Administrator for Institutions and Asset Management; Lynn Cline, Deputy Associate Administrator for Space Flight; Bob Sieck, former Director of Space Shuttle Processing at KSC; and Jim Wetherbee, astronaut and Technical Assistant to the Director of Safety and Mission Assurance at Johnson Space Center. Following their remarks, members of the panel entertained questions and comments from the audience.

  17. KSC-04PD-1120

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. -- Jim Wetherbee, astronaut and Technical Assistant to the Director of Safety and Mission Assurance at Johnson Space Center addresses KSC employees assembled in the Training Auditorium for a Culture Change Process All Hands Meeting. The purpose of the meeting was for employees to gain further insight into the Agencys Vision for Space Exploration and the direction cultural change will take at KSC in order to assume its role within this vision. Other participants included James W. Kennedy, KSC director; Jim Jennings, Deputy Associate Administrator for Institutions and Asset Management; Lynn Cline, Deputy Associate Administrator for Space Flight; and Bob Sieck, former Director of Space Shuttle Processing at KSC. Following their remarks, members of the panel entertained questions and comments from the audience.

  18. KSC-04PD-1113

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. -- KSC employees assemble in the Training Auditorium for a Culture Change Process All Hands Meeting. The purpose of the meeting was for employees to gain further insight into the Agencys Vision for Space Exploration and the direction cultural change will take at KSC in order to assume its role within this vision. Panel members included James W. Kennedy, KSC director; Jim Jennings, Deputy Associate Administrator for Institutions and Asset Management; Lynn Cline, Deputy Associate Administrator for Space Flight; Bob Sieck, former Director of Space Shuttle Processing at KSC; and Jim Wetherbee, astronaut and Technical Assistant to the Director of Safety and Mission Assurance at the Johnson Space Center. Following their remarks, members of the panel entertained questions and comments from the audience.

  19. KSC-04PD-1122

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. -- The panel members participating in the Culture Change Process All Hands Meeting entertain questions and comments from the audience assembled in the Training Auditorium. From left, they are James W. Kennedy, KSC director; Jim Jennings, Deputy Associate Administrator for Institutions and Asset Management; Lynn Cline, Deputy Associate Administrator for Space Flight; Bob Sieck, former Director of Space Shuttle Processing at KSC; and Jim Wetherbee, astronaut and Technical Assistant to the Director of Safety and Mission Assurance at Johnson Space Center. The purpose of the meeting was for employees to gain further insight into the Agencys Vision for Space Exploration and the direction cultural change will take at KSC in order to assume its role within this vision.

  20. KSC-04PD-1115

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. -- Jim Jennings, Deputy Associate Administrator for Institutions and Asset Management addresses KSC employees assembled in the Training Auditorium for a Culture Change Process All Hands Meeting. The purpose of the meeting was for employees to gain further insight into the Agencys Vision for Space Exploration and the direction cultural change will take at KSC in order to assume its role within this vision. Other participants included James W. Kennedy, KSC director; Lynn Cline, Deputy Associate Administrator for Space Flight; Bob Sieck, former Director of Space Shuttle Processing at KSC; and Jim Wetherbee, astronaut and Technical Assistant to the Director of Safety and Mission Assurance at Johnson Space Center. Following their remarks, members of the panel entertained questions and comments from the audience.

  1. KSC-04PD-1116

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. -- Lynn Cline, Deputy Associate Administrator for Space Flight addresses KSC employees assembled in the Training Auditorium for a Culture Change Process All Hands Meeting. The purpose of the meeting was for employees to gain further insight into the Agencys Vision for Space Exploration and the direction cultural change will take at KSC in order to assume its role within this vision. Other participants included James W. Kennedy, KSC director; Jim Jennings, Deputy Associate Administrator for Institutions and Asset Management; Bob Sieck, former Director of Space Shuttle Processing at KSC; and Jim Wetherbee, astronaut and Technical Assistant to the Director of Safety and Mission Assurance at Johnson Space Center. Following their remarks, members of the panel entertained questions and comments from the audience.

  2. KSC-04PD-1121

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. -- The panel members participating in the Culture Change Process All Hands Meeting entertain questions and comments from the audience assembled in the Training Auditorium. From left, they are James W. Kennedy, KSC director; Jim Jennings, Deputy Associate Administrator for Institutions and Asset Management; Lynn Cline, Deputy Associate Administrator for Space Flight; Bob Sieck, former Director of Space Shuttle Processing at KSC; and Jim Wetherbee, astronaut and Technical Assistant to the Director of Safety and Mission Assurance at Johnson Space Center. The purpose of the meeting was for employees to gain further insight into the Agencys Vision for Space Exploration and the direction cultural change will take at KSC in order to assume its role within this vision.

  3. KSC-04PD-1114

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. -- Jim Jennings, Deputy Associate Administrator for Institutions and Asset Management addresses KSC employees assembled in the Training Auditorium for a Culture Change Process All Hands Meeting. The purpose of the meeting was for employees to gain further insight into the Agencys Vision for Space Exploration and the direction cultural change will take at KSC in order to assume its role within this vision. Other participants included James W. Kennedy, KSC director; Lynn Cline, Deputy Associate Administrator for Space Flight; Bob Sieck, former Director of Space Shuttle Processing at KSC; and Jim Wetherbee, astronaut and Technical Assistant to the Director of Safety and Mission Assurance at Johnson Space Center. Following their remarks, members of the panel entertained questions and comments from the audience.

  4. KSC-04PD-1110

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. -- Center Director James W. Kennedy addresses KSC employees assembled in the Training Auditorium for a Culture Change Process All Hands Meeting. The purpose of the meeting was for employees to gain further insight into the Agencys Vision for Space Exploration and the direction cultural change will take at KSC in order to assume its role within this vision. Other participants included Jim Jennings, Deputy Associate Administrator for Institutions and Asset Management; Lynn Cline, Deputy Associate Administrator for Space Flight; Bob Sieck, former Director of Space Shuttle Processing at KSC; and Jim Wetherbee, astronaut and Technical Assistant to the Director of Safety and Mission Assurance at Johnson Space Center. Following their remarks, members of the panel entertained questions and comments from the audience.

  5. KSC-04PD-1119

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. -- Jim Wetherbee, astronaut and Technical Assistant to the Director of Safety and Mission Assurance at Johnson Space Center addresses KSC employees assembled in the Training Auditorium for a Culture Change Process All Hands Meeting. The purpose of the meeting was for employees to gain further insight into the Agencys Vision for Space Exploration and the direction cultural change will take at KSC in order to assume its role within this vision. Other participants included James W. Kennedy, KSC director; Jim Jennings, Deputy Associate Administrator for Institutions and Asset Management; Lynn Cline, Deputy Associate Administrator for Space Flight; and Bob Sieck, former Director of Space Shuttle Processing at KSC. Following their remarks, members of the panel entertained questions and comments from the audience.

  6. KSC-2010-4575

    NASA Image and Video Library

    2010-09-05

    ORLANDO, Fla. -- During the 2010 Tom Joyner Family Reunion, space activist and actress Nichelle Nichols talks to attendees at the Gaylord Palms Convention Center in Orlando, Fla. To encourage student attendees to focus on pursuing careers in science, technology, engineering and mathematics (STEM), NASA featured some of its greatest legends and trailblazers during a panel discussion at the reunion event. In the 1960s, Nichols played communications officer Lieutenant Uhura in the Star Trek television series. Other panel members included NASA astronaut Leland Melvin, Christine Darden, Lew Braxton, Robyn Gordon and Jim Jennings. NASA's Education Office sponsored the panel discussion and educational activities as part of the agency's "Summer of Innovation" initiative and the federal "Educate to Innovate" campaign. Photo credit: NASA/Amanda Diller

  7. KSC00pp1241

    NASA Image and Video Library

    2000-09-06

    KSC Director Roy Bridges (right) views the new Checkout and Launch Control System (CLCS) at the Hypergolic Maintenance Facility (HMF). Looking on (left to right)are NASA Associate Administrator for Space Flight Joseph Rothenberg, United Space Alliance Lead IPT Frank Norris, KSC Deputy Center Director Jim Jennings, and Deputy Director of External Relations & Business Development Joe Gordon (behind Bridges). At the controls is Charles Novak, HMF programmer, United Space Alliance. The CLCS was declared operational in a ribbon cutting ceremony earlier. The new control room will be used to process the Orbital Maneuvering System pods and Forward Reaction Control System modules at the HMF. This hardware is removed from Space Shuttle orbiters and routinely taken to the HMF for checkout and servicing

  8. KSC-00pp1241

    NASA Image and Video Library

    2000-09-06

    KSC Director Roy Bridges (right) views the new Checkout and Launch Control System (CLCS) at the Hypergolic Maintenance Facility (HMF). Looking on (left to right)are NASA Associate Administrator for Space Flight Joseph Rothenberg, United Space Alliance Lead IPT Frank Norris, KSC Deputy Center Director Jim Jennings, and Deputy Director of External Relations & Business Development Joe Gordon (behind Bridges). At the controls is Charles Novak, HMF programmer, United Space Alliance. The CLCS was declared operational in a ribbon cutting ceremony earlier. The new control room will be used to process the Orbital Maneuvering System pods and Forward Reaction Control System modules at the HMF. This hardware is removed from Space Shuttle orbiters and routinely taken to the HMF for checkout and servicing

  9. KENNEDY SPACE CENTER, FLA. - Officials of the NASA-Kennedy Space Center and the state of Florida pose for a group portrait at a dedication and ribbon-cutting ceremony for the Space Life Sciences Lab at the new lab. From left are Capt. Winston Scott, executive director of the Florida Space Authority; Dr. Robert J. Ferl, director of Space Agriculture Biotechnology Research and Education (SABRE), University of Florida; Charlie Quincy, chief of the Biological Sciences Office, Kennedy Space Center; Jose Perez-Morales, NASA Project Manager for the Space Life Sciences Lab; Jim Kennedy, director of the Kennedy Space Center; The Honorable Toni Jennings, lieutenant governor of the state of Florida; Frank T. Brogan, president of the Florida Atlantic University; and Dr. Samuel Durrance, executive director of the Florida Space Research Institute. Completed in August, the facility encompasses more than 100,000 square feet and was formerly known as the Space Experiment Research and Processing Laboratory or SERPL. The state, through the Florida Space Authority, built the research lab which is host to NASA, NASA’s Life Sciences Services contractor Dynamac Corp., Bionetics Corp., and researchers from the University of Florida. Dynamac Corp. leases the facility. The Florida Space Research Institute is responsible for gaining additional tenants from outside the NASA community.

    NASA Image and Video Library

    2003-11-19

    KENNEDY SPACE CENTER, FLA. - Officials of the NASA-Kennedy Space Center and the state of Florida pose for a group portrait at a dedication and ribbon-cutting ceremony for the Space Life Sciences Lab at the new lab. From left are Capt. Winston Scott, executive director of the Florida Space Authority; Dr. Robert J. Ferl, director of Space Agriculture Biotechnology Research and Education (SABRE), University of Florida; Charlie Quincy, chief of the Biological Sciences Office, Kennedy Space Center; Jose Perez-Morales, NASA Project Manager for the Space Life Sciences Lab; Jim Kennedy, director of the Kennedy Space Center; The Honorable Toni Jennings, lieutenant governor of the state of Florida; Frank T. Brogan, president of the Florida Atlantic University; and Dr. Samuel Durrance, executive director of the Florida Space Research Institute. Completed in August, the facility encompasses more than 100,000 square feet and was formerly known as the Space Experiment Research and Processing Laboratory or SERPL. The state, through the Florida Space Authority, built the research lab which is host to NASA, NASA’s Life Sciences Services contractor Dynamac Corp., Bionetics Corp., and researchers from the University of Florida. Dynamac Corp. leases the facility. The Florida Space Research Institute is responsible for gaining additional tenants from outside the NASA community.

  10. Citations Prize 2013

    NASA Astrophysics Data System (ADS)

    Cherry, Simon; Ruffle, Jon

    2014-06-01

    Physics in Medicine and Biology (PMB) awards its 'Citations Prize' to the authors of the original research paper that has received the most citations in the preceding five years (according to the Institute for Scientific Information (ISI)). The lead author of the winning paper is presented with the Rotblat Medal (named in honour of Professor Sir Joseph Rotblat, a Nobel Prize winner who also was the second—and longest serving—Editor of PMB, from 1961-1972). The winner of the 2013 Citations Prize for the paper which has received the most citations in the previous five years (2008-2012) is Figure. Figure. Four of the prize winning authors. From left to right: Thomas Istel (Philips), Jens-Peter Schlomka (with medal, MorphoDetection), Ewald Roessl (Philips), and Gerhard Martens (Philips). Title: Experimental feasibility of multi-energy photon-counting K-edge imaging in pre-clinical computed tomography Authors: Jens Peter Schlomka1, Ewald Roessl1, Ralf Dorscheid2, Stefan Dill2, Gerhard Martens1, Thomas Istel1, Christian Bäumer3, Christoph Herrmann3, Roger Steadman3, Günter Zeitler3, Amir Livne4 and Roland Proksa1 Institutions: 1 Philips Research Europe, Sector Medical Imaging Systems, Hamburg, Germany 2 Philips Research Europe, Engineering & Technology, Aachen, Germany 3 Philips Research Europe, Sector Medical Imaging Systems, Aachen, Germany 4 Philips Healthcare, Global Research and Advanced Development, Haifa, Israel Reference: Schlomka et al 2008 Phys. Med. Biol. 53 4031-47 This paper becomes the first to win both this citations prize and also the PMB best paper prize (The Roberts Prize), which it won for the year 2008. Discussion of the significance of the winning paper can be found in this medicalphysicsweb article from the time of the Roberts Prize win (http://medicalphysicsweb.org/cws/article/research/39907). The author's enthusiasm for their prototype spectral CT system has certainly been reflected in the large number of citations the paper subsequently has

  11. Bathythermal distribution, maturity, and growth of lake trout strains stocked in U.S. waters of Lake Ontario, 1978-1993

    USGS Publications Warehouse

    Elrod, Joseph H.; O'Gorman, Robert; Schneider, Clifford P.

    1996-01-01

    Bathythermal distributions, sexual maturity, and growth of lake trout (Salvelinus namaycush) strains stocked in Lake Ontario were determined for fish collected with trawls and gill nets in 1978-93. The purpose was to augment the basis for deciding which strains to continue stocking in an effort to reestablish a self-sustaining population. The Clearwater Lake (CWL) strain was found in shallower, warmer water than all other strains; the Seneca Lake (SEN) strain was usually shallower than the Jenny Lake (JEN) and Lake Superior (SUP) strains at ages 1 and 2 but was usually deeper at age 3 and older. Depth distribution of the 'Ontario strain'--from gametes of several strains that survived to maturity in Lake Ontario-- was similar to that of the SEN and SUP strains. About half the males matured at age 4 and half the females at age 5; males < 500 mm and females < 600 mm long were rarely mature. Least-sqaures mean lengths and weights of the CWL strain were greater than those of all other strains through age 4. At age 7 and older, CWL and JEN fish were generally smaller than all other strains. Means lengths and weights of males and females of the same age and strain frequently differed at age 4 and older. Growth in weight at age 4 and older was not associated with biomass indices of prey fishes. Differences in growth rates among strains were associated with bathythermal distribution which is a heritable trait. Weight-length regressions differed by year, sex, and stage of maturity but were rarely different among strains. Competition for space appeared to affect condition of large lake trout. Growth rates and maturity schedules provide little basis for recommending stocking one strain in preference to another. Depth ranges of strains overlapped widely, but lake trout occupied only about one-fourth of available bottom habitat. Stocking several strains should be continued to maximize use of sustainable habitat.

  12. [Roald Amundsen--a study of personality].

    PubMed

    Albretsen, C S

    1996-12-10

    Roald Amundsen is the most famous of the Norwegian polar explorers. His ancestors came from a group of islands south-east of the Oslofjord. From being fishermen and sailors, they progressed to becoming captains and shipowners in the course of two generations. Amundsen's father, Jens, stayed at sea until his ship went down with all the crew. Roald was 14 years of age at the time, the youngest of four competing brothers. Jens had left the close-knit local family community before that, and bought a flat in the capital, Oslo, so that his sons could get a better education. Roald's mother wanted him to study medicine. He did as she wished for a time, but was not at all interested. When his mother died, he abruptly left the university and went to sea, which had been the tradition in his family for decades. As a young boy he was an admirer of Sir John Franklin and his explorers of the Northwest Passage. Fridtjof Nansen became his ideal. The biographies about Roald Amundsen are very diverging--some hold him a hero, others reflect a strongly critical attitude. Here, the author tries to define his personality and places him firmly within the narcissistic domain. His tendency to seek the company of married women, but to take immediate flight when they really became interested reflects an Oedipus complex from before puberty. The tragic death of his father, the sea captain, may have been a supposition; puberty can be seen as a period of coping with ambivalence towards an earlier idealized father. His genius combined ambitious goals with a sharp eye for details as regards the equipment used in his expeditions. In his travels in the Arctic and the Antartic he was driven forward by the energy of the nation. His heroic death, trying to save his earlier "enemy", Nobile, was probably caused by an urge for self-destruction.

  13. ICI bites demerger bullet, Zeneca guns for [Brit pounds]1. 3-billion rights issue

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jackson, D.; Alperowicz, N.

    1993-03-03

    Any lingering doubts as to ICI's (London) intentions to follow through its demerger proposals were dispelled last week. The company will hive off its bioscience business into Zeneca Group plc, which will make a [Brit pounds]1.3-billion ($1.9 billion) rights issue in June 1993. Shareholders, whose approval for the historic move will be sought in late May, will receive one fully paid Zeneca share for each ICI share. Proceeds from the rights issue will be used to reduce Zeneca's indebtedness to ICI by about 70%. Acknowledging that ICI had spread the jam too thinly' during its expansion in the 1980s, chiefmore » executive Ronnie Hampel says the new ICI will be a cost-conscious, no-frills' organization and that businesses that failed to perform would be restructured or closed. He is not expecting any help from the economy' in 1993. Of ICI's remaining petrochemicals and plastics businesses, Hampel says that despite stringent measures to reduce the cost base[hor ellipsis]it is clear they will not reach a return on capital that will justify reinvestment by ICI.' He does not see them as closure candidates but as 'businesses that will require further restructuring.' Hampel notes a dozen clearly identified areas for expansion,' including paints, catalysts, titanium dioxide, and chlorofluorocarbon replacements. Losses in materials, where substantial rationalization has failed to halt the slide, will be reduced on completion of the DuPont deal - expected by midyear. Further measures' would be necessary for the residual bit of advanced materials in the US,' he says.« less

  14. KSC-03pd0312

    NASA Image and Video Library

    2003-02-07

    KENNEDY SPACE CENTER, FLA. - A Columbia Crew Memorial Service is held at the Shuttle Landing Facility for KSC employees and invited guests. Florida Gov. Jeb Bush is at the podium. Seated to his right are NASA Associate Deputy Administrator for Institutions & Asset Management James L. Jennings, NASA Administrator Sean O'Keefe, and Columbia's first pilot and former KSC Director Robert Crippen. The Columbia and her crew of seven were lost on Feb. 1, 2003, over East Texas as they returned to Earth after a 16-day research mission. Taking part in the service were NASA Administrator Sean O’Keefe, former KSC Director Robert Crippen, astronaut Jim Halsell, several employees, area clergymen, and members of Patrick Air Force Base. The service concluded with a “Missing Man Formation Fly Over” by NASA T-38 jet aircraft.

  15. KSC-03pd0288

    NASA Image and Video Library

    2003-02-07

    KENNEDY SPACE CENTER, FLA. - A Columbia Crew Memorial Service is held at the Shuttle Landing Facility for KSC employees and invited guests, including (from left) NASA Associate Deputy Administrator for Institutions and Asset Management James L. Jennings, Florida Gov. Jeb Bush, NASA Administrator Sean O'Keefe, and Columbia's first pilot and former KSC Director Robert Crippen. The Columbia and her crew of seven were lost on Feb. 1, 2003, over East Texas as they returned to Earth after a 16-day research mission. Taking part in the service were NASA Administrator Sean O’Keefe, former KSC Director Robert Crippen, astronaut Jim Halsell, several employees, area clergymen, and members of Patrick Air Force Base. The service concluded with a “Missing Man Formation Fly Over” by NASA T-38 jet aircraft.

  16. Study of network resource allocation based on market and game theoretic mechanism

    NASA Astrophysics Data System (ADS)

    Liu, Yingmei; Wang, Hongwei; Wang, Gang

    2004-04-01

    We work on the network resource allocation issue concerning network management system function based on market-oriented mechanism. The scheme is to model the telecommunication network resources as trading goods in which the various network components could be owned by different competitive, real-world entities. This is a multidisciplinary framework concentrating on the similarity between resource allocation in network environment and the market mechanism in economic theory. By taking an economic (market-based and game theoretic) approach in routing of communication network, we study the dynamic behavior under game-theoretic framework in allocating network resources. Based on the prior work of Gibney and Jennings, we apply concepts of utility and fitness to the market mechanism with an intention to close the gap between experiment environment and real world situation.

  17. Information systems as a quality management tool in clinical laboratories

    NASA Astrophysics Data System (ADS)

    Schmitz, Vanessa; Rosecler Bez el Boukhari, Marta

    2007-11-01

    This article describes information systems as a quality management tool in clinical laboratories. The quality of laboratory analyses is of fundamental importance for health professionals in aiding appropriate diagnosis and treatment. Information systems allow the automation of internal quality management processes, using standard sample tests, Levey-Jennings charts and Westgard multirule analysis. This simplifies evaluation and interpretation of quality tests and reduces the possibility of human error. This study proposes the development of an information system with appropriate functions and costs for the automation of internal quality control in small and medium-sized clinical laboratories. To this end, it evaluates the functions and usability of two commercial software products designed for this purpose, identifying the positive features of each, so that these can be taken into account during the development of the proposed system.

  18. Live from Antarctica: the Coldest, Windiest Place on Earth

    NASA Technical Reports Server (NTRS)

    1994-01-01

    In this first part of a four part 'Passport to Knowledge Special', hosted by Camille Jennings from Maryland Public Television, children from Maryland and Texas schools had the opportunity to directly interact with and ask questions of scientists and researchers in Antarctica live. The physical characteristics of Antarctica are featured, along with their effects on the human and microbiological organisms living in the region. The reasons behind the clothing worn in the Antarctic and the importance of the meteorological station are featured. Interviews with Professor Ian Dolziel (U of Texas) and Lt. commander John Joseph, NSFA (the head of the Navy Meteorology Center) occur with the school children, along with actual video footage of the surrounding geological features and geography. The 'Weatherops' is located at McMurdo Station, Antarctica.

  19. Live from Antarctica: The coldest, windiest place on Earth

    NASA Astrophysics Data System (ADS)

    In this first part of a four part 'Passport to Knowledge Special', hosted by Camille Jennings from Maryland Public Television, children from Maryland and Texas schools had the opportunity to directly interact with and ask questions of scientists and researchers in Antarctica live. The physical characteristics of Antarctica are featured, along with their effects on the human and microbiological organisms living in the region. The reasons behind the clothing worn in the Antarctic and the importance of the meteorological station are featured. Interviews with Professor Ian Dolziel (U of Texas) and Lt. commander John Joseph, NSFA (the head of the Navy Meteorology Center) occur with the school children, along with actual video footage of the surrounding geological features and geography. The 'Weatherops' is located at McMurdo Station, Antarctica.

  20. Mortality in a teaching hospital during junior doctor changeover: a regional and national comparison.

    PubMed

    Sharma, Vijay; Proctor, Ian; Winstanley, Alison

    2013-03-01

    Concerns about whether the junior doctor changeover in the UK is associated with an increased risk of death have been reawakened by a retrospective study (Jen et al, 2009). Examination of overall mortality data has consistently failed to demonstrate any increase in mortality during the changeover. However, regional and national trends may mask this increase, so a study was undertaken to compare mortality in a busy London teaching hospital with regional and national trends. No evidence of an increase in mortality in August was found for any of the time periods examined, even after comparison with regional and national trends. The authors conclude that examination of overall mortality data is a blunt and impractical instrument for settling the question of whether an increase in morbidity and mortality occurs. Preventable morbidity and mortality should be audited.

  1. Alvin expeditionary hotline

    NASA Astrophysics Data System (ADS)

    This note is call for dive requests, coordinated to the extent practical, from those scientists interested in opportunities for an Alvin/Atlantis II expedition to some remote area. In an effort to facilitate planning for Alvin and to help focus the attention of investigators with diverse scientific interests in remote areas, Feenan Jennings of Texas A & M University, College Station, who chairs the University-National Oceanographic Laboratory System's (UNOLS') Alvin Review Committee (ARC), has announced establishment of an Alvin planning bulletin board on electronic mail. The bulletin board, ALVIN.PLANNING, is to help inform potential users of community interest in conducting Alvin/Atlantis II research projects, especially those involving expeditions to remote areas. ALVIN.PLANNING will be implemented early in 1990. Notice and further details will be broadcast throughout the ocean community.

  2. 78 FR 12346 - Jennings Low-Effect Habitat Conservation Plan for the Morro Shoulderband Snail, Community of Los...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-22

    ... Fish and Wildlife Office, U.S. Fish and Wildlife Service, 2493 Portola Road, Suite B, Ventura, CA 93003... the following activities: ``to harass, harm, pursue, hunt, shoot, wound, kill, trap, capture, or... located at 460 Los Osos Valley Road in western portion of Los Osos, an unincorporated community of San...

  3. Selections from Kung-Jen JIH-PAO (Source Span: 25 May-16 July 1961 Number 9 Communist China

    DTIC Science & Technology

    1961-08-31

    Social Science Research Council. The contents of this material in no way renr-orents the policies, views, or attitudes of the U. S. ’Government or...advance the . awareness and correct the attitude toward production in advancing the quality of products,’ Since April, the quality of the principal...the principal one was the workers1 recognition of and attitude towards product quality, ■ ■ When this plant was established in 1958, the condition

  4. Selections From Kung-Jen JIH-PAO (Source Span: 9 May-30 June 1961) Number 7 -Communist China.

    DTIC Science & Technology

    1961-08-17

    sulphate Ammonium hydrogen carbonate Sodium borate Titaniüm-iron powder Sodium fluoride Silicon dioxide Barium chloride beryllium carbonate ...Vinzenstrasse, 22a :■ P. 0. Box 3521 Aachen, Germany Washington 7> B.C. , Institute de Sociologie Solvay Rue du Chatelain, k9 Brussels, Belgium State... Sodium nitrite Specifications Pure n industrial Boric Acid " A^ua ammonia " Magnesium sulphate Industrial Manganese tedroxide Pure

  5. KSC-03pd0300

    NASA Image and Video Library

    2003-02-07

    KENNEDY SPACE CENTER, FLA. - A Columbia Crew Memorial Service is held at the Shuttle Landing Facility for KSC employees and invited guests. Columbia's first pilot and former KSC Director Robert Crippen is at the podium. Seated to his right are NASA Associate Deputy Administrator for Institutions and Asset Management James L. Jennings, Florida Gov. Jeb Bush, and NASA Administrator Sean O'Keefe. The Columbia and her crew of seven were lost on Feb. 1, 2003, over East Texas as they returned to Earth after a 16-day research mission. Taking part in the service were NASA Administrator Sean O’Keefe, former KSC Director Robert Crippen, astronaut Jim Halsell, several employees, area clergymen, and members of Patrick Air Force Base. The service concluded with a “Missing Man Formation Fly Over” by NASA T-38 jet aircraft.

  6. KSC-03pd0299

    NASA Image and Video Library

    2003-02-07

    KENNEDY SPACE CENTER, FLA. - A Columbia Crew Memorial Service is held at the Shuttle Landing Facility for KSC employees and invited guests. NASA Administrator Sean O'Keefe is at the podium. Seated to his right are NASA Associate Deputy Administrator for Institutions and Asset Management James L. Jennings, Florida Gov. Jeb Bush, and Columbia's first pilot and former KSC Director Robert Crippen. The Columbia and her crew of seven were lost on Feb. 1, 2003, over East Texas as they returned to Earth after a 16-day research mission. Taking part in the service were NASA Administrator Sean O’Keefe, former KSC Director Robert Crippen, astronaut Jim Halsell, several employees, area clergymen, and members of Patrick Air Force Base. The service concluded with a “Missing Man Formation Fly Over” by NASA T-38 jet aircraft.

  7. KSC-03pd0298

    NASA Image and Video Library

    2003-02-07

    KENNEDY SPACE CENTER, FLA. - A Columbia Crew Memorial Service is held at the Shuttle Landing Facility for KSC employees and invited guests. NASA Administrator Sean O'Keefe is at the podium. Seated to his right are NASA Associate Deputy Administrator for Institutions and Asset Management James L. Jennings, Florida Gov. Jeb Bush, and Columbia's first pilot and former KSC Director Robert Crippen. The Columbia and her crew of seven were lost on Feb. 1, 2003, over East Texas as they returned to Earth after a 16-day research mission. Taking part in the service were NASA Administrator Sean O’Keefe, former KSC Director Robert Crippen, astronaut Jim Halsell, several employees, area clergymen, and members of Patrick Air Force Base. The service concluded with a “Missing Man Formation Fly Over” by NASA T-38 jet aircraft.

  8. KSC-04PD-2010

    NASA Technical Reports Server (NTRS)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. At Gainesville Elementary School, a NASA Explorer School in Gainesville, Ga., astronaut Leland Melvin hands a patch to a student for answering a question. Melvin joined Jim Jennings, deputy associate administrator for Institutions and Asset Management at NASA Headquarters, on the visit to the school to share the new vision for space exploration with the next generation of explorers. Melvin talked about the importance of teamwork and what it takes for mission success. Also visiting was KSC Deputy Director Woodrow Whitlow Jr., who talked with students about our destiny as explorers, NASAs stepping stone approach to exploring Earth, the Moon, Mars and beyond, how space impacts our lives, and how people and machines rely on each other in space. Melvin talked about the importance of teamwork and what it takes for mission success.

  9. Flu, Floods, and Fire: Ethical Public Health Preparedness.

    PubMed

    Phelan, Alexandra L; Gostin, Lawrence O

    2017-05-01

    Even as public health ethics was developing as a field, major incidents such as 9/11 and the SARS epidemic propelled discourse around public health emergency preparedness and response. Policy and practice shifted to a multidisciplinary approach, recognizing the broad range of potential threats to public health, including biological, physical, radiological, and chemical threats. This propelled the development of surveillance systems to detect incidents, laboratory capacities to rapidly test for potential threats, and therapeutic and social countermeasures to prepare for and respond to a range of hazards. In bringing public health ethics and emergency preparedness together, Emergency Ethics: Public Health Preparedness and Response adds depth and complexity to both fields. As global threats continue to emerge, the book, edited by Bruce Jennings, John D. Arras, Drue H. Barrett, and Barbara A. Ellis, will offer a vital compass. © 2017 The Hastings Center.

  10. Experimental Quantum Randomness Processing Using Superconducting Qubits

    NASA Astrophysics Data System (ADS)

    Yuan, Xiao; Liu, Ke; Xu, Yuan; Wang, Weiting; Ma, Yuwei; Zhang, Fang; Yan, Zhaopeng; Vijay, R.; Sun, Luyan; Ma, Xiongfeng

    2016-07-01

    Coherently manipulating multipartite quantum correlations leads to remarkable advantages in quantum information processing. A fundamental question is whether such quantum advantages persist only by exploiting multipartite correlations, such as entanglement. Recently, Dale, Jennings, and Rudolph negated the question by showing that a randomness processing, quantum Bernoulli factory, using quantum coherence, is strictly more powerful than the one with classical mechanics. In this Letter, focusing on the same scenario, we propose a theoretical protocol that is classically impossible but can be implemented solely using quantum coherence without entanglement. We demonstrate the protocol by exploiting the high-fidelity quantum state preparation and measurement with a superconducting qubit in the circuit quantum electrodynamics architecture and a nearly quantum-limited parametric amplifier. Our experiment shows the advantage of using quantum coherence of a single qubit for information processing even when multipartite correlation is not present.

  11. Study protocol: evaluation of 'JenMe', a commercially-delivered weight management program for adolescents: a randomised controlled trial.

    PubMed

    Dordevic, Aimee L; Bonham, Maxine P; Ware, Robert S; Brennan, Leah; Truby, Helen

    2015-06-19

    Early lifestyle intervention with overweight and obese adolescents could help to avoid serious health events in early adulthood, ultimately alleviating some of the strain on the public health system due to obesity-related morbidity. Commercial weight loss programs have wide reach into the community setting, and have demonstrated success in long term weight management in adults, beyond that of current public health care. Commercial weight-management programs have not been evaluated as a method of delivery for overweight and obese adolescents. This study aims to evaluate the efficacy of a new adolescent weight management program in a commercial environment. One hundred and forty adolescents, 13 to 17 years old, will be randomised to either a weight management program intervention or a wait-listed group for 12 weeks. The commercial program will consist of a combined dietary and lifestyle approach targeting improved health behaviours for weight-loss or weight-stability. Participants will be overweight or obese (above the 85(th) percentile for BMI) and without existing co-morbidities. Outcome measures will be assessed at baseline and after 12 weeks. Primary outcome measures will be changes in BMI Z-score and waist-height ratio. Secondary outcome measures will include changes in behaviour, physical activity and psychosocial wellbeing. Intervention participants will be followed up at 6 months following completion of the initial program. Ethics approval has been granted from the Monash University Human Research Ethics Committee (CF11/3687-2011001940). This independent evaluation of a weight management program for adolescents, delivered in a commercial setting, will provide initial evidence for the effectiveness of such programs; which may offer adolescents an avenue of weight-management with ongoing support prior to the development of obesity related co-morbidities. The protocol for this study is registered with the International Clinical Trials Registry ISRCTN13602313.

  12. Pressurized Slot Testing to Determine Thermo-Mechanical Properties of Lithophysal Tuff at Yucca Mountain Nevada.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    George, James T.; Sobolik, Steven R.; Lee, Moo Y.

    The study described in this report involves heated and unheated pressurized slot testing to determine thermo-mechanical properties of the Tptpll (Tertiary, Paintbrush, Topopah Spring Tuff Formation, crystal poor, lower lithophysal) and Tptpul (upper lithophysal) lithostratigraphic units at Yucca Mountain, Nevada. A large volume fraction of the proposed repository at Yucca Mountain may reside in the Tptpll lithostratigraphic unit. This unit is characterized by voids, or lithophysae, which range in size from centimeters to meters, making a field program an effective method of measuring bulk thermal-mechanical rock properties (thermal expansion, rock mass modulus, compressive strength, time-dependent deformation) over a range ofmore » temperature and rock conditions. The field tests outlined in this report provide data for the determination of thermo-mechanical properties of this unit. Rock-mass response data collected during this field test will reduce the uncertainty in key thermal-mechanical modeling parameters (rock-mass modulus, strength and thermal expansion) for the Tptpll lithostratigraphic unit, and provide a basis for understanding thermal-mechanical behavior of this unit. The measurements will be used to evaluate numerical models of the thermal-mechanical response of the repository. These numerical models are then used to predict pre- and post-closure repository response. ACKNOWLEDGEMENTS The authors would like to thank David Bronowski, Ronnie Taylor, Ray E. Finley, Cliff Howard, Michael Schuhen (all SNL) and Fred Homuth (LANL) for their work in the planning and implementation of the tests described in this report. This is a reprint of SAND2004-2703, which was originally printed in July 2004. At that time, it was printed for a restricted audience. It has now been approved for unlimited release.« less

  13. Toward the prediction of class I and II mouse major histocompatibility complex-peptide-binding affinity: in silico bioinformatic step-by-step guide using quantitative structure-activity relationships.

    PubMed

    Hattotuwagama, Channa K; Doytchinova, Irini A; Flower, Darren R

    2007-01-01

    Quantitative structure-activity relationship (QSAR) analysis is a cornerstone of modern informatics. Predictive computational models of peptide-major histocompatibility complex (MHC)-binding affinity based on QSAR technology have now become important components of modern computational immunovaccinology. Historically, such approaches have been built around semiqualitative, classification methods, but these are now giving way to quantitative regression methods. We review three methods--a 2D-QSAR additive-partial least squares (PLS) and a 3D-QSAR comparative molecular similarity index analysis (CoMSIA) method--which can identify the sequence dependence of peptide-binding specificity for various class I MHC alleles from the reported binding affinities (IC50) of peptide sets. The third method is an iterative self-consistent (ISC) PLS-based additive method, which is a recently developed extension to the additive method for the affinity prediction of class II peptides. The QSAR methods presented here have established themselves as immunoinformatic techniques complementary to existing methodology, useful in the quantitative prediction of binding affinity: current methods for the in silico identification of T-cell epitopes (which form the basis of many vaccines, diagnostics, and reagents) rely on the accurate computational prediction of peptide-MHC affinity. We have reviewed various human and mouse class I and class II allele models. Studied alleles comprise HLA-A*0101, HLA-A*0201, HLA-A*0202, HLA-A*0203, HLA-A*0206, HLA-A*0301, HLA-A*1101, HLA-A*3101, HLA-A*6801, HLA-A*6802, HLA-B*3501, H2-K(k), H2-K(b), H2-D(b) HLA-DRB1*0101, HLA-DRB1*0401, HLA-DRB1*0701, I-A(b), I-A(d), I-A(k), I-A(S), I-E(d), and I-E(k). In this chapter we show a step-by-step guide into predicting the reliability and the resulting models to represent an advance on existing methods. The peptides used in this study are available from the AntiJen database (http://www.jenner.ac.uk/AntiJen). The PLS method

  14. Diurnal Variations of Titan's Surface Temperatures From Cassini -CIRS Observations

    NASA Astrophysics Data System (ADS)

    Cottini, Valeria; Nixon, Conor; Jennings, Don; Anderson, Carrie; Samuelson, Robert; Irwin, Patrick; Flasar, F. Michael

    The Cassini Composite Infrared Spectrometer (CIRS) observations of Saturn's largest moon, Titan, are providing us with the ability to detect the surface temperature of the planet by studying its outgoing radiance through a spectral window in the thermal infrared at 19 m (530 cm-1) characterized by low opacity. Since the first acquisitions of CIRS Titan data the in-strument has gathered a large amount of spectra covering a wide range of latitudes, longitudes and local times. We retrieve the surface temperature and the atmospheric temperature pro-file by modeling proper zonally averaged spectra of nadir observations with radiative transfer computations. Our forward model uses the correlated-k approximation for spectral opacity to calculate the emitted radiance, including contributions from collision induced pairs of CH4, N2 and H2, haze, and gaseous emission lines (Irwin et al. 2008). The retrieval method uses a non-linear least-squares optimal estimation technique to iteratively adjust the model parameters to achieve a spectral fit (Rodgers 2000). We show an accurate selection of the wide amount of data available in terms of footprint diameter on the planet and observational conditions, together with the retrieved results. Our results represent formal retrievals of surface brightness temperatures from the Cassini CIRS dataset using a full radiative transfer treatment, and we compare to the earlier findings of Jennings et al. (2009). The application of our methodology over wide areas has increased the planet coverage and accuracy of our knowledge of Titan's surface brightness temperature. In particular we had the chance to look for diurnal variations in surface temperature around the equator: a trend with slowly increasing temperature toward the late afternoon reveals that diurnal temperature changes are present on Titan surface. References: Irwin, P.G.J., et al.: "The NEMESIS planetary atmosphere radiative transfer and retrieval tool" (2008). JQSRT, Vol. 109, pp

  15. ``Dual Society Ever Precedes through Trevor SWAN & Wassily Leontief''

    NASA Astrophysics Data System (ADS)

    Maksoed, Wh-

    ``Dual Society'' introduced by E.F. Schumacher are classified as non-stabile society who easy to shakes by politics uncertainties.in Robert J. Barro & X. Sala-i-Martin: ``Convergence''states: `` a key economic issue is whether poor countries or regions tend to grow faster than rich ones''.For growth models from Roy Forbes Herrod & EvseyDomar, three assumptions described by Eduardo Ley are?[U+2639]i). output is proportional to capital,(ii). Investment ex anteequals saving & (iii) saving proportional to output. Underlines Trevor SWAN, developing countries differ significantly among themselves. Economic growth models comprises Herrod-Domar growth model, Solow growth model & endogenous growth model.Further, for five stages of economic groeth from Rostov of Leontief technology, ever retrieves the Jens Beckert:''Institutional Isomorphism revisited: Convergence & Divergence in Institutional Change''instead Frumkin's ``Institutional Isomorphism & Public Sector Organizations''. Acknowledgment devotes to theLates HE. Mr. BrigadierGeneral-TNI[rtd].Prof. Ir. HANDOJO.

  16. Joseph Lovell, MD (1788-1836): First US army surgeon general.

    PubMed

    Craig, Stephen C

    2016-08-01

    Joseph Lovell, trained in medicine at Harvard and in military medicine/surgery by the War of 1812, became the first Surgeon General to sit on the reorganised army staff at the tender age of 29 in 1818. With a keen intellect, medical acumen, and wartime experiences for his tools and a close supporting relationship with Commanding General Jacob Jennings Brown and Secretary of War John C Calhoun (1728-1850), Lovell constructed an efficient and effective organisational and administrative framework for the new Medical Department of the US Army. Moreover, he not only redefined the role of the American military physician but also established the professional dignity, respectability and value of the medical officer among line officers and staff. Lovell's 18-year tenure came to an abrupt end, but the operational framework he created became both foundation and legacy for his successors. © Author(s) 2016.

  17. Closing ceremonies of the FIRST Southeast Regional robotics competition

    NASA Technical Reports Server (NTRS)

    2000-01-01

    At the conclusion of the FIRST (For Inspiration and Recognition of Science and Technology) Southeast Regional competition held at the KSC Visitor Complex, KSC Deputy Director for Business Operations Jim Jennings speaks to the teams and other attendees. At left is Gregg Gale, with Walt Disney World, which is the site of the national competition (at EPCOT) April 6-8. Teams of high school students from all over the country tested the limits of their imagination using robots they designed, with the support of business and engineering professionals and corporate sponsors, to compete in a technological battle against other schools' robots. Of the 30 high school teams competing at the Southeast Regional event, 16 were Florida teams co-sponsored by NASA and KSC contractors. Local high schools participating are Astronaut, Bayside, Cocoa Beach, Eau Gallie, Melbourne, Melbourne Central Catholic, Palm Bay, Rockledge, Satellite, and Titusville.

  18. KSC-00pp0344

    NASA Image and Video Library

    2000-03-11

    At the conclusion of the FIRST (For Inspiration and Recognition of Science and Technology) Southeast Regional competition held at the KSC Visitor Complex, KSC Deputy Director for Business Operations Jim Jennings speaks to the teams and other attendees. At left is Gregg Gale, with Walt Disney World, which is the site of the national competition (at EPCOT) April 6-8. Teams of high school students from all over the country tested the limits of their imagination using robots they designed, with the support of business and engineering professionals and corporate sponsors, to compete in a technological battle against other schools' robots. Of the 30 high school teams competing at the Southeast Regional event, 16 were Florida teams co-sponsored by NASA and KSC contractors. Local high schools participating are Astronaut, Bayside, Cocoa Beach, Eau Gallie, Melbourne, Melbourne Central Catholic, Palm Bay, Rockledge, Satellite, and Titusville

  19. KSC00pp0344

    NASA Image and Video Library

    2000-03-11

    At the conclusion of the FIRST (For Inspiration and Recognition of Science and Technology) Southeast Regional competition held at the KSC Visitor Complex, KSC Deputy Director for Business Operations Jim Jennings speaks to the teams and other attendees. At left is Gregg Gale, with Walt Disney World, which is the site of the national competition (at EPCOT) April 6-8. Teams of high school students from all over the country tested the limits of their imagination using robots they designed, with the support of business and engineering professionals and corporate sponsors, to compete in a technological battle against other schools' robots. Of the 30 high school teams competing at the Southeast Regional event, 16 were Florida teams co-sponsored by NASA and KSC contractors. Local high schools participating are Astronaut, Bayside, Cocoa Beach, Eau Gallie, Melbourne, Melbourne Central Catholic, Palm Bay, Rockledge, Satellite, and Titusville

  20. Generation of ozone foam and its application for disinfection

    NASA Astrophysics Data System (ADS)

    Hiragaki, Keisuke; Ishimaru, Tomiya; Nakanishi, Masaru; Muraki, Ryouji; Nieda, Masanori; Yamabe, Chobei

    2015-07-01

    Generated ozone foam was applied to the disinfection of Pseudomonas fluorescens. The effect of disinfection has been confirmed experimentally and new equipment for the disinfection of hands using this ozone foam has been put on the market for the practical use. The ozone foam was produced in the foam generator after mixing the water including surfactant (30 mL/min) and air including ozone (1000 ppm = 2.14 g/m3 ~ 1600 ppm = 3.4 g/m3, 300 mL/min). The liquid-to-gas ratio is 100 L/m3. The concentration of dissolved ozone in the thin liquid films of the bubbles was about 3 mg/L which was measured by the chemical method of the KI absorption and titration of sodium thiosulfate solution. The disinfection test samples were prepared using the PET disk on which Pseudomonas fluorescens of its number of more than 108 were attached. Test sample was inserted into ozone foam set on the glass plate for one to 6 min. The survival rate log (N/N0 decreased with time and its value of about-2.6 (i.e., ~1/400) was obtained at 6 min (2 min × 3 times repeated). It was also confirmed that the ozone foam was useful for the disinfection of hands. For more effective disinfection (in case of taking a long time for foam melting), the ozone foam was broken by force and changed into ozone water by which the survival rate decreased ×4 (i.e., N/N0 = 1/10 000) at 4 ~ 6 min. Contribution to the topical issue "The 14th International Symposium on High Pressure Low Temperature Plasma Chemistry (HAKONE XIV)", edited by Nicolas Gherardi, Ronny Brandenburg and Lars Stollenwark

  1. Reflections on urban science teacher-student self-efficacy dynamics

    NASA Astrophysics Data System (ADS)

    Hagiwara, Sumi; Maulucci, Maria S. Rivera; Ramos, S. Lizette

    2011-12-01

    This forum article consists of commentaries—authored by Sumi Hagiwara, Maria S. Rivera Maulucci and Lizette Ramos—on the feature article by Virginia Jennings Bolshakova, Carla C. Johnson, and Charlene M. Czerniak. We reflect on a series of questions that take retrospective, introspective, and prospective views of self-efficacy in science education. We review selected studies that explore some of the historical developments and methodological approaches in the literature and examine a teacher-student self-efficacy system model that shows the ways in which teachers' and students' self-efficacy judgments are based upon multiple individual and shared components, such as identity and social interaction within the classroom and school. We close with a call for the design of measures of teacher-student self-efficacy systems, so that we can begin to tailor professional development experiences to the goals and motivations of individual and collective groups of teachers and students in ways that accommodate the unique cultural features of their classrooms and foster student self-efficacy.

  2. Automated technical validation--a real time expert system for decision support.

    PubMed

    de Graeve, J S; Cambus, J P; Gruson, A; Valdiguié, P M

    1996-04-15

    Dealing daily with various machines and various control specimens provides a lot of data that cannot be processed manually. In order to help decision-making we wrote specific software coping with the traditional QC, with patient data (mean of normals, delta check) and with criteria related to the analytical equipment (flags and alarms). Four machines (3 Ektachem 700 and 1 Hitachi 911) analysing 25 common chemical tests are controlled. Every day, three different control specimens and one more once a week (regional survey) are run on the various pieces of equipment. The data are collected on a 486 microcomputer connected to the central computer. For every parameter the standard deviation is compared with the published acceptable limits and the Westgard's rules are computed. The mean of normals is continuously monitored. The final decision induces either an alarm sound and the print-out of the cause of rejection or, if no alarms happen, the daily print-out of recorded data, with or without the Levey Jennings graphs.

  3. Sampling Melt Ponds

    NASA Image and Video Library

    2017-12-08

    On July 10, 2011, Jens Ehn of Scripps Institution of Oceanography (left), and Christie Wood of Clark University (right), scooped water from melt ponds on sea ice in the Chukchi Sea. The water was later analyzed from the Healy's onboard science lab. The ICESCAPE mission, or "Impacts of Climate on Ecosystems and Chemistry of the Arctic Pacific Environment," is a NASA shipborne investigation to study how changing conditions in the Arctic affect the ocean's chemistry and ecosystems. The bulk of the research took place in the Beaufort and Chukchi seas in summer 2010 and 2011. Credit: NASA/Kathryn Hansen NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

  4. Quark Matter 2011 (QM11) Quark Matter 2011 (QM11)

    NASA Astrophysics Data System (ADS)

    2011-12-01

    International Advisory Committee Antinori, FedericoPaic, Guy Braun-Munzinger, PeterPajares, Carlos Cifarelli, LuisaPeitzmann, Thomas Erazmus, BarbaraRedlich, Krzysztof Eskola, KariRiccati, Lodovico Gaardhøje, Jens JørgenRoland, Gunther Gale, CharlesRoy, Christelle Gelis, FrancoisSchukraft, Jürgen Giubellino, PaoloSinha, Bikash Greiner, CarstenSrivastava, Dinesh Gyulassy, MiklosStachel, Johanna Harris, JohnSteinberg, Peter Hatsuda, TetsuoStroth, Joachim Heinz, UlrichSugitate, Toru Jacak, BarbaraTserruya, Itzhak Karsch, FrithjofVelkovska, Julia Kharzeev, DimaWang, Enke Kodama, TakeshiWang, Xin, Nian Lévai, PéterWessels, Johannes Manko, VladislavXu, Nu Müller, BerndtZajc, William Ollitrault, Jean-Yves Organizing Committee Arleo, FrancoisDupieux, Pascal Bastid, NicoleFurget, Christophe Bourgeois, Marie-LaureGranier de Cassagnac, Raphael Bregant, MarcoGuernane, Rachid Carminati, FedericoHervet, Carnita Castillo, JavierKuhn, Christian Cheynis, BrigitteOlivier, Nathalie Conesa, DelValle, Zaida Connor, MichelleRenshall, Lucy Crochet, PhilippeSuire, Christophe Delagrange, HuguesTihinen, Ulla Program Committee Schutz, Yves (Chair)Baldisseri, Alberto Wiedemann, Urs (co-Chair)Safarik, Karel Aurenche, Patrick

  5. Representing energy efficiency diagnosis strategies in cognitive work analysis.

    PubMed

    Hilliard, Antony; Jamieson, Greg A

    2017-03-01

    This article describes challenges encountered in applying Jens Rasmussen's Cognitive Work Analysis (CWA) framework to the practice of energy efficiency Monitoring & Targeting (M&T). Eight theoretic issues encountered in the analysis are described with respect to Rasmussen's work and the modeling solutions we adopted. We grappled with how to usefully apply Work Domain Analysis (WDA) to analyze categories of domains with secondary purposes and no ideal grain of decomposition. This difficulty encouraged us to pursue Control Task (ConTA) and Strategies (StrA) analysis, which are under-explored as bases for interface design. In ConTA we found M&T was best represented by two interlinked work functions; one controlling energy, the other maintaining knowledge representations. From StrA, we identified a popular representation-dependent strategy and inferred information required to diagnose faults in system performance and knowledge representation. This article presents and discusses excerpts from our analysis, and outlines their application to diagnosis support tools. Copyright © 2015 Elsevier Ltd. All rights reserved.

  6. KSC-06pd0470

    NASA Image and Video Library

    2006-03-10

    KENNEDY SPACE CENTER, FLA. - Florida's Lt. Governor Toni Jennings speaks during the V.I.P. luncheon at the 2006 FIRST Robotics Regional Competition held March 9-11 at the University of Central Florida in Orlando. The FIRST Robotics Competition challenges teams of young people and their mentors to solve a common problem in a six-week timeframe using a standard "kit of parts" and a common set of rules. Teams build robots from the parts and enter them in a series of competitions. FIRST, which is based on "For Inspiration and Recognition of Science and Technology," redefines winning for these students. Teams are rewarded for excellence in design, demonstrated team spirit, gracious professionalism and maturity, and ability to overcome obstacles. Scoring the most points is a secondary goal. Winning means building partnerships that last. NASA and the University of Central Florida are co-sponsors of the regional event, which this year included more than 50 teams. Photo credit: NASA/Kim Shiflett

  7. First Lady Hillary Clinton is greeted by NASA Administrator Goldin

    NASA Technical Reports Server (NTRS)

    1999-01-01

    First Lady Hillary Rodham Clinton and her daughter, Chelsea, are greeted by NASA Administrator Daniel S. Goldin upon their arrival at the Skid Strip at Cape Canaveral Air Station. Next to Gold are (from left) Deputy Director for Business Operations Jim Jennings and Mrs. Goldin. Mrs. Clinton and Chelsea are here to view the launch of Space Shuttle mission STS-93, scheduled for 12:36 a.m. EDT July 20. Much attention has been generated over the launch due to Commander Eileen M. Collins, the first woman to serve as commander of a Shuttle mission. The primary payload of the five- day mission is the Chandra X-ray Observatory, which will allow scientists from around the world to study some of the most distant, powerful and dynamic objects in the universe. The new telescope is 20 to 50 times more sensitive than any previous X- ray telescope and is expected to unlock the secrets of supernovae, quasars and black holes.

  8. Recollection training and transfer effects in older adults: successful use of a repetition-lag procedure.

    PubMed

    Jennings, Janine M; Webster, Lauren M; Kleykamp, Bethea A; Dagenbach, Dale

    2005-09-01

    We examined an approach aimed at training consciously-controlled recollection, introduced by Jennings and Jacoby (2003) , for its ability to replicate and generalize. A continuous recognition task, requiring recollection to identify the occurrence of repeated items over gradually increasing lag intervals (number of intervening items between the first and second presentation of a repeated word), was given to a group of older adults twice a week for three weeks. Pre-and-post training performance was assessed on multiple measures and compared with a recognition practice and no contact control group. Recollection training proved successful; accurate identification of repeated items increased across a lag interval of 2 to 18 intervening items. Post-training gains following recollection training were found on n-back, self-ordered pointing, source discrimination and digit symbol substitution, but not with reading span or the CVLT-II. No changes were identified in the other groups. Gains from recollection training seem to transfer successfully in older adults.

  9. KSC-99pp0888

    NASA Image and Video Library

    1999-07-19

    First Lady Hillary Rodham Clinton and her daughter, Chelsea, are greeted by NASA Administrator Daniel S. Goldin upon their arrival at the Skid Strip at Cape Canaveral Air Station. Next to Gold are (from left) Deputy Director for Business Operations Jim Jennings and Mrs. Goldin. Mrs. Clinton and Chelsea are here to view the launch of Space Shuttle mission STS-93, scheduled for 12:36 a.m. EDT July 20. Much attention has been generated over the launch due to Commander Eileen M. Collins, the first woman to serve as commander of a Shuttle mission. The primary payload of the five-day mission is the Chandra X-ray Observatory, which will allow scientists from around the world to study some of the most distant, powerful and dynamic objects in the universe. The new telescope is 20 to 50 times more sensitive than any previous X-ray telescope and is expected to unlock the secrets of supernovae, quasars and black holes

  10. KSC-03PD-0811

    NASA Technical Reports Server (NTRS)

    2003-01-01

    KENNEDY SPACE CENTER, FLA. - NASA/Kennedy Space Center Director Roy Bridges (background) observes as Florida Lt. Gov. Toni Jennings interacts with students at a display of space structures built from Lego blocks at the 2003 Southeastern Regional FIRST Robotic Competition. The competition is being held at the University of Central Florida (UCF) in Orlando, March 20-23. Forty student teams from around the country are participating in the event that pits team-built gladiator robots against each other in an athletic-style competition. The teams are sponsored by NASA/Kennedy Space Center, The Boeing Company/Brevard Community College, and Lockheed Martin Space Operations/Mission Systems for the nonprofit organization For Inspiration and Recognition of Science and Technology, known as FIRST. The vision of FIRST is to inspire in the youth of our nation an appreciation of science and technology and an understanding that mastering these disciplines can enrich the lives of all mankind.

  11. KSC-03pd0811

    NASA Image and Video Library

    2003-03-21

    KENNEDY SPACE CENTER, FLA. - NASA/Kennedy Space Center Director Roy Bridges (background) observes as Florida Lt. Gov. Toni Jennings interacts with students at a display of space structures built from Lego blocks at the 2003 Southeastern Regional FIRST Robotic Competition. The competition is being held at the University of Central Florida (UCF) in Orlando, March 20-23. Forty student teams from around the country are participating in the event that pits team-built gladiator robots against each other in an athletic-style competition. The teams are sponsored by NASA/Kennedy Space Center, The Boeing Company/Brevard Community College, and Lockheed Martin Space Operations/Mission Systems for the nonprofit organization For Inspiration and Recognition of Science and Technology, known as FIRST. The vision of FIRST is to inspire in the youth of our nation an appreciation of science and technology and an understanding that mastering these disciplines can enrich the lives of all mankind.

  12. Prediction of B-cell linear epitopes with a combination of support vector machine classification and amino acid propensity identification.

    PubMed

    Wang, Hsin-Wei; Lin, Ya-Chi; Pai, Tun-Wen; Chang, Hao-Teng

    2011-01-01

    Epitopes are antigenic determinants that are useful because they induce B-cell antibody production and stimulate T-cell activation. Bioinformatics can enable rapid, efficient prediction of potential epitopes. Here, we designed a novel B-cell linear epitope prediction system called LEPS, Linear Epitope Prediction by Propensities and Support Vector Machine, that combined physico-chemical propensity identification and support vector machine (SVM) classification. We tested the LEPS on four datasets: AntiJen, HIV, a newly generated PC, and AHP, a combination of these three datasets. Peptides with globally or locally high physicochemical propensities were first identified as primitive linear epitope (LE) candidates. Then, candidates were classified with the SVM based on the unique features of amino acid segments. This reduced the number of predicted epitopes and enhanced the positive prediction value (PPV). Compared to four other well-known LE prediction systems, the LEPS achieved the highest accuracy (72.52%), specificity (84.22%), PPV (32.07%), and Matthews' correlation coefficient (10.36%).

  13. The 12C/ 13C isotopic ratio in Titan hydrocarbons from Cassini/CIRS infrared spectra

    NASA Astrophysics Data System (ADS)

    Nixon, C. A.; Achterberg, R. K.; Vinatier, S.; Bézard, B.; Coustenis, A.; Irwin, P. G. J.; Teanby, N. A.; de Kok, R.; Romani, P. N.; Jennings, D. E.; Bjoraker, G. L.; Flasar, F. M.

    2008-06-01

    We have analyzed infrared spectra of Titan recorded by the Cassini Composite Infrared Spectrometer (CIRS) to measure the isotopic ratio 12C/ 13C in each of three chemical species in Titan's stratosphere: CH 4, C 2H 2 and C 2H 6. This is the first measurement of 12C/ 13C in any C 2 molecule on Titan, and the first measurement of 12CH 4/ 13CH 4 (non-deuterated) on Titan by remote sensing. Our spectra cover five widely-spaced latitudes, 65° S to 71° N and we have searched for both latitude variability of 12C/ 13C within a given species, and also for differences between the 12C/ 13C in the three gases. For CH 4 alone, we find C12/C13=76.6±2.7 (1- σ), essentially in agreement with the 12CH 4/ 13CH 4 measured by the Huygens Gas Chromatograph/Mass Spectrometer instrument (GCMS) [Niemann, H.B., and 17 colleagues, 2005. Nature 438, 779-784]: 82.3±1.0, and also with measured values in H 13CN and 13CH 3D by CIRS at lower precision [Bézard, B., Nixon, C., Kleiner, I., Jennings, D., 2007. Icarus 191, 397-400; Vinatier, S., Bézard, B., Nixon, C., 2007. Icarus 191, 712-721]. For the C 2 species, we find C12/C13=84.8±3.2 in C 2H 2 and 89.8±7.3 in C 2H 6, a possible trend of increasingly value with molecular mass, although these values are both compatible with the Huygens GCMS value to within error bars. There are no convincing trends in latitude. Combining all fifteen measurements, we obtain a value of C12/C13=80.8±2.0, also compatible with GCMS. Therefore, the evidence is mounting that 12C/ 13C is some 8% lower on Titan than on the Earth (88.9, inorganic standard), and lower than typical for the outer planets ( 88±7 [Sada, P.V., McCabe, G.H., Bjoraker, G.L., Jennings, D.E., Reuter, D.C., 1996. Astrophys. J. 472, 903-907]). There is no current model for this enrichment, and we discuss several mechanisms that may be at work.

  14. Novel homologous lactate transporter improves L-lactic acid production from glycerol in recombinant strains of Pichia pastoris.

    PubMed

    de Lima, Pollyne Borborema Almeida; Mulder, Kelly Cristina Leite; Melo, Nadiele Tamires Moreira; Carvalho, Lucas Silva; Menino, Gisele Soares; Mulinari, Eduardo; de Castro, Virgilio H; Dos Reis, Thaila F; Goldman, Gustavo Henrique; Magalhães, Beatriz Simas; Parachin, Nádia Skorupa

    2016-09-15

    Crude glycerol is the main byproduct of the biodiesel industry. Although it can have different applications, its purification is costly. Therefore, in this study a biotechnological route has been proposed for further utilization of crude glycerol in the fermentative production of lactic acid. This acid is largely utilized in food, pharmaceutical, textile, and chemical industries, making it the hydroxycarboxylic acid with the highest market potential worldwide. Currently, industrial production of lactic acid is done mainly using sugar as the substrate. Thus here, for the first time, Pichia pastoris has been engineered for heterologous L-lactic acid production using glycerol as a single carbon source. For that, the Bos taurus lactate dehydrogenase gene was introduced into P. pastoris. Moreover, a heterologous and a novel homologous lactate transporter have been evaluated for L-lactic acid production. Batch fermentation of the P. pastoris X-33 strain producing LDHb allowed for lactic acid production in this yeast. Although P. pastoris is known for its respiratory metabolism, batch fermentations were performed with different oxygenation levels, indicating that lower oxygen availability increased lactic acid production by 20 %, pushing the yeast towards a fermentative metabolism. Furthermore, a newly putative lactate transporter from P. pastoris named PAS has been identified by search similarity with the lactate transporter from Saccharomyces cerevisiae Jen1p. Both heterologous and homologous transporters, Jen1p and PAS, were evaluated in one strain already containing LDH activity. Fed-batch experiments of P. pastoris strains carrying the lactate transporter were performed with the batch phase at aerobic conditions followed by an aerobic oxygen-limited phase where production of lactic acid was favored. The results showed that the strain containing PAS presented the highest lactic acid titer, reaching a yield of approximately 0.7 g/g. We showed that P. pastoris has a

  15. PREFACE: 7th International Conference on Applied Electrostatics (ICAES-2012)

    NASA Astrophysics Data System (ADS)

    Li, Jie

    2013-03-01

    ICAES is an important conference organized every four years by the Committee on Electrostatics of the Chinese Physical Society, which serves as a forum for scientists, educators and engineers interested in the fundamentals, applications, disasters and safety of electrostatics, etc. In recent years, new techniques, applications and fundamental theories on electrostatics have developed considerably. ICAES-7, held in Dalian, China, from 17-19 September 2012, aimed to provide a forum for all scholars to report the newest developments in electrostatics, to probe the questions that scholars faced and to discuss fresh ideas related to electrostatics. ICAES-7 was co-organized and hosted by Dalian University of Technology, and was sponsored by the Ministry of Education of China, the National Natural Science Foundation of China, Dalian University of Technology, Nanjing Suman Electronics Co. Ltd (Suman, China), Shekonic (Yangzhou Shuanghong, China) Electric/Mechanical Co. Ltd, and Suzhou TA&A Ultra Clean Technology Co. Ltd. (China). On behalf of the organizing committee of ICAES-7, I express my great appreciation for their support of the conference. Over 160 scholars and engineers from many countries including Croatia, The Czech Republic, D.P.R. Korea, Germany, Japan, Malaysia, Poland, Russia, the United States of America, China attended ICAES-7, and the conference collected and selected 149 papers for publication. The subjects of those papers cover the fundamentals of electrostatics, electrostatic disaster and safety, and electrostatic application (e.g. precipitation, pollutant control, biological treatment, mixture separation and food processing, etc). I cordially thank all authors and attendees for their support, and my appreciation is also given to the conference honorary chair, the organizing committee and advisory committee, and the conference secretaries for their hard work. ICAES-7 is dedicated to the memory of Professor Jen-Shih Chang (professor emeritus in the

  16. A perspective on quantum integrability in many-body-localized and Yang-Baxter systems

    NASA Astrophysics Data System (ADS)

    Moore, Joel E.

    2017-10-01

    Two of the most active areas in quantum many-particle dynamics involve systems with an unusually large number of conservation laws. Many-body-localized systems generalize ideas of Anderson localization by disorder to interacting systems. While localization still exists with interactions and inhibits thermalization, the interactions between conserved quantities lead to some dramatic differences from the Anderson case. Quantum integrable models such as the XXZ spin chain or Bose gas with delta-function interactions also have infinite sets of conservation laws, again leading to modifications of conventional thermalization. A practical way to treat the hydrodynamic evolution from local equilibrium to global equilibrium in such models is discussed. This paper expands upon a presentation at a discussion meeting of the Royal Society on 7 February 2017. The work described was carried out with a number of collaborators, including Jens Bardarson, Vir Bulchandani, Roni Ilan, Christoph Karrasch, Siddharth Parameswaran, Frank Pollmann and Romain Vasseur. This article is part of the themed issue 'Breakdown of ergodicity in quantum systems: from solids to synthetic matter'.

  17. KSC-99pp0929

    NASA Image and Video Library

    1999-07-21

    Entering the Banana Creek viewing site, First Lady Hillary Rodham Clinton is joined by NASA Administrator Daniel Goldin (right), and in the background, Deputy Director of Business Operations Jim Jennings (far left) and Director of Installation Operations Marv Jones (right, behind Goldin). Mrs. Clinton and others are at the site to watch the second launch attempt of STS-93. Moments before the first scheduled launch, July 20, STS-93 was scrubbed at the T-7 second mark in the countdown due to an indication of a high concentration of hydrogen in an aft engine compartment. The reading proved to be a false alarm. The launch was rescheduled for July 22 at 12:28 a.m. Much attention has been generated over STS-93 due to Commander Eileen M. Collins, the first woman to serve as commander of a Shuttle mission. The primary payload of the five-day mission is the Chandra X-ray Observatory, which will allow scientists from around the world to study some of the most distant, powerful and dynamic objects in the universe

  18. Understanding nocturnal enuresis and its treatments.

    PubMed

    Potter, D C; Wogoman, H A; Nietch, P

    1999-09-01

    Nocturnal enuresis is a condition that touches the lives of many children around the world. Affected children and their parents may experience feelings of guilt, frustration, and anxiety because of their lack of control over the situation. Nurses can play an important role in providing education to families in regards to the causes and treatment of enuresis. It is important for nurses to understand the problem of bedwetting thoroughly so they can assist the family in making an informed decision about the various options currently available. Nocturnal enuresis (bedwetting) is a common disorder that frequently results in frustration and stress on not only the children that experience it, but their parents as well. Scharf, Pravda, Jennings, Kauffman, and Ringel (1987) note that an estimated five to seven million children in America experience enuresis. Enuresis has family and psychosocial aspects, along with financial concerns. Therefore, it is important for nurses to be aware of the causes of enuresis, how it affects the family, and the current treatments that are available.

  19. Human embryonic stem cell research debates: a Confucian argument

    PubMed Central

    Tsai, D

    2005-01-01

    The author proposes that the "gradualist" position is more plausible than the other two positions. Confucius's moral principle of jen, which proposes a unique theory of "love of gradation", and the principle of yi, which advocates "due treatment for persons", are then explored. The author then argues that our moral obligations to do good to other living organisms, persons, and our families are different. Putting together the "gradualist" position on the human embryo, and Confucius's theories of "love of gradation" and "due treatment for persons", the author concludes that the early embryo has less ethical significance than the later fetus and adult human. The moral obligation we have toward persons is clearer and stronger than that which we have toward human embryos. Embryo research is justifiable if it brings enormous welfare to human persons that cannot be otherwise achieved. The "love of gradation" requires us, however, to extend love and respect towards other entities according to their different status. We should therefore be very cautious in using human embryos for research, acknowledging the gradualist nature of their moral status. PMID:16269558

  20. Modeling a Large Heterogeneous Set of CIRS Spectra of Titan: The ν4 band of 12C2HD

    NASA Astrophysics Data System (ADS)

    Boyle, Robert J.; Jennings, Donald, Dr.; Bjoraker, Gordon, Dr.

    2018-01-01

    A technique has been developed which allows global average abundances of trace species to be derived from large heterogeneous data sets using the Spectral Synthsis Program [SSP] originally developed by Kunde & McGuire (1974). The method was applied to a large average of 24,000 individual spectra of Titan from the Composite Infrared Spectrometer (CIRS) on Cassini. The spectra were centered on the 581.6 cm‑1 ν4 band of 12C2HD and were taken in order to obtain a global average abundance for this species. The spectra covered a wide range of planetary latitudes and emission angles. The results obtained are generally in agreement with those derived by Coustenis et al. (2008) derived from their analysis of the ν5 band of this species at 678 cm‑1.ReferencesCoustenis, A., Jennings, D. E., Jolly, A., Bnilan, Y., Nixon, C. A., Vinatier, S., Gautier, D., Bjoraker, G. L., Romani, P. N., Carlson, R. C., & Flasar, F. 2008, Icarus, 197, 539-548.Kunde, V. G. & Maguire, W. C. 1974, JQSRT, 14, 803-817

  1. Classification and reduction of pilot error

    NASA Technical Reports Server (NTRS)

    Rogers, W. H.; Logan, A. L.; Boley, G. D.

    1989-01-01

    Human error is a primary or contributing factor in about two-thirds of commercial aviation accidents worldwide. With the ultimate goal of reducing pilot error accidents, this contract effort is aimed at understanding the factors underlying error events and reducing the probability of certain types of errors by modifying underlying factors such as flight deck design and procedures. A review of the literature relevant to error classification was conducted. Classification includes categorizing types of errors, the information processing mechanisms and factors underlying them, and identifying factor-mechanism-error relationships. The classification scheme developed by Jens Rasmussen was adopted because it provided a comprehensive yet basic error classification shell or structure that could easily accommodate addition of details on domain-specific factors. For these purposes, factors specific to the aviation environment were incorporated. Hypotheses concerning the relationship of a small number of underlying factors, information processing mechanisms, and error types types identified in the classification scheme were formulated. ASRS data were reviewed and a simulation experiment was performed to evaluate and quantify the hypotheses.

  2. First Lady Hillary Clinton returns to KSC for second launch attempt

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Entering the Banana Creek viewing site, First Lady Hillary Rodham Clinton is joined by NASA Administrator Daniel Goldin (right), and in the background, Deputy Director of Business Operations Jim Jennings (far left) and Director of Installation Operations Marv Jones (right, behind Goldin). Mrs. Clinton and others are at the site to watch the second launch attempt of STS-93. Moments before the first scheduled launch, July 20, STS-93 was scrubbed at the T-7 second mark in the countdown due to an indication of a high concentration of hydrogen in an aft engine compartment. The reading proved to be a false alarm. The launch was rescheduled for July 22 at 12:28 a.m. Much attention has been generated over STS-93 due to Commander Eileen M. Collins, the first woman to serve as commander of a Shuttle mission. The primary payload of the five-day mission is the Chandra X-ray Observatory, which will allow scientists from around the world to study some of the most distant, powerful and dynamic objects in the universe.

  3. Live from Antarctica, Volume 4

    NASA Technical Reports Server (NTRS)

    1994-01-01

    In this fourth video of a four part 'Passport to Knowledge Special', hosted by Camille Moody Jennings from Maryland Public Television, children from Maryland and Alaska public schools had the opportunity to directly interact with and ask questions of scientists and researchers from the Antarctic, and learn about the different geological and meteorological research going on in the Antarctic and McMurdo Base at McMurdo Sound. The scientists questioned included: Donal Manahan (biologist from Un. of So. California), who described some of the geological features from Hut Point, the historic hut built by Capt. Scott in 1902; Sridar Anandakrishnan (Penn State Un.) whose research includes ice plate movement of the central ice sheet and earthquakes and how they affect the sheet; and Lt. j.g. Kate McNitt, who spends her winters investigating the trace gases, aerosols, CFC's and ozone levels over the Antarctic area that are affecting the seasonal ozone hole that appears in that region. Historical film footage of Capt. Scott's exploration of the Antarctic is included.

  4. Live from Antarctica, volume 4

    NASA Astrophysics Data System (ADS)

    In this fourth video of a four part 'Passport to Knowledge Special', hosted by Camille Moody Jennings from Maryland Public Television, children from Maryland and Alaska public schools had the opportunity to directly interact with and ask questions of scientists and researchers from the Antarctic, and learn about the different geological and meteorological research going on in the Antarctic and McMurdo Base at McMurdo Sound. The scientists questioned included: Donal Manahan (biologist from Un. of So. California), who described some of the geological features from Hut Point, the historic hut built by Capt. Scott in 1902; Sridar Anandakrishnan (Penn State Un.) whose research includes ice plate movement of the central ice sheet and earthquakes and how they affect the sheet; and Lt. j.g. Kate McNitt, who spends her winters investigating the trace gases, aerosols, CFC's and ozone levels over the Antarctic area that are affecting the seasonal ozone hole that appears in that region. Historical film footage of Capt. Scott's exploration of the Antarctic is included.

  5. Subjective Ratings of Beauty and Aesthetics: Correlations With Statistical Image Properties in Western Oil Paintings

    PubMed Central

    Lehmann, Thomas; Redies, Christoph

    2017-01-01

    For centuries, oil paintings have been a major segment of the visual arts. The JenAesthetics data set consists of a large number of high-quality images of oil paintings of Western provenance from different art periods. With this database, we studied the relationship between objective image measures and subjective evaluations of the images, especially evaluations on aesthetics (defined as artistic value) and beauty (defined as individual liking). The objective measures represented low-level statistical image properties that have been associated with aesthetic value in previous research. Subjective rating scores on aesthetics and beauty correlated not only with each other but also with different combinations of the objective measures. Furthermore, we found that paintings from different art periods vary with regard to the objective measures, that is, they exhibit specific patterns of statistical image properties. In addition, clusters of participants preferred different combinations of these properties. In conclusion, the results of the present study provide evidence that statistical image properties vary between art periods and subject matters and, in addition, they correlate with the subjective evaluation of paintings by the participants. PMID:28694958

  6. CONFERENCE NOTE: European Optical Society, Topical Meeting Optical Metrology and Nanotechnology, Engelberg, Switzerland, 27 30 March 1994

    NASA Astrophysics Data System (ADS)

    1993-01-01

    This meeting, organized by the Paul Scherrer Institute's Department of Applied Solid State Physics, will be held from 27 30 March 1994 at the Hotel Regina-Titlis, Engelberg, Switzerland. The aim is to bring together scientists from two important fields of current research and increasing industrial relevance. Optical metrology is a traditional discipline of applied optics which reached the nanometre scale a long time ago. Nanotechnology is setting new limits and represents a major challenge to metrology, as well as offering new opportunities to optics. The meeting is intended to help define a common future for optical metrology and nanotechnology. Topics to be covered include: nanometre position control and measuring techniques ultrahigh precision interferometry scanning probe microscopy (AFM, SNOM, etc.) surface modification by scanning probe methods precision surface fabrication and characterization nanolithography micro-optics, diffractive optics components, including systems and applications subwavelength optical structures synthetic optical materials structures and technologies for X-ray optics. For further information please contact: Jens Gobrecht (Secretary), Paul Scherrer Institute, CH-5232 Villigen-PSI, Switzerland.Tel. (41)56992529; Fax (41) 5698 2635.

  7. Respiratory Sinus Arrhythmia: A Potential Indicator of Cholinergic Toxicosis in Rhesus Monkeys (Macaca mulatta)

    DTIC Science & Technology

    1990-01-01

    n \\0 .0A0 m M 0 N NLn w LaL w x 0%0 N eft0 d O 0r.I’ 0 N a’%.AO0O m I ~ *C P- CO - 0en0 11 _r 0 N 0IAIAOOOIAO CYfn O Q 90 II * 0 0O A - IA I M*l- 0l 0...8217% 0 ) O 0%InC" P. r- m _n-"M f.- MOn -c OA)mCPJP 4 as In r- -M D0mCM0 ff,\\ . *%0 0 m c n N %0W Te- 0M0r l nt)chi 0C -% \\ % NLN :940 a 0% n-O0 CO Y c-r...0 -Ten f-)( . 0 0 ellN~jen Nln )~ 0 ŕr-WmNCŘ\\ M-0 r - 1 I.0 r * l C \\ nae 0f.;oenor%o 0_ * ~ 4o Yo, M0 " 0 \\m=%r- 0% P~- C o \\0 %0o- \\0 n NY CjCjM

  8. Dynamics in a ratio-dependent predator-prey model with predator harvesting

    NASA Astrophysics Data System (ADS)

    Xiao, Dongmei; Li, Wenxia; Han, Maoan

    2006-12-01

    The objective of this paper is to study systematically the dynamical properties of a ratio-dependent predator-prey model with nonzero constant rate predator harvesting. It is shown that the model has at most two equilibria in the first quadrant and can exhibit numerous kinds of bifurcation phenomena, including the bifurcation of cusp type of codimension 2 (i.e., Bogdanov-Takens bifurcation), the subcritical and supercritical Hopf bifurcations. These results reveal far richer dynamics compared to the model with no harvesting and different dynamics compared to the model with nonzero constant rate prey harvesting in [D. Xiao, L. Jennings, Bifurcations of a ratio-dependent predator-prey system with constant rate harvesting, SIAM Appl. Math. 65 (2005) 737-753]. Biologically, it is shown that nonzero constant rate predator harvesting can prevent mutual extinction as a possible outcome of the predator prey interaction, and remove the singularity of the origin, which was regarded as "pathological behavior" for a ratio-dependent predator prey model in [P. Yodzis, Predator-prey theory and management of multispecies fisheries, Ecological Applications 4 (2004) 51-58].

  9. New particle formation from sulfuric acid and amines: Similarities and differences between mono-, di-, and trimethylamines

    NASA Astrophysics Data System (ADS)

    Olenius, Tinja; Halonen, Roope; Kurtén, Theo; Henschel, Henning; Kupiainen-Määttä, Oona; Ortega, Ismael K.; Vehkamäki, Hanna; Riipinen, Ilona

    2017-04-01

    Amines are organic base species that are emitted to the atmosphere from both anthropogenic and natural sources. Both theoretical and laboratory studies suggest that mono-, di-, and trimethylamines (MMA, DMA, and TMA, respectively) are capable of enhancing the initial steps of sulfuric acid-driven aerosol particle formation much more strongly than ammonia (Kurtén et al., 2008; Jen et al., 2014). Despite the potential importance for atmospheric new particle formation, quantitative estimates on the emissions and thermochemical properties of amines remain relatively uncertain. Because of this and also due to computational reasons, recent large-scale modeling studies have treated sulfuric acid-amine nucleation by introducing a single surrogate amine species, the total emissions of which combine together MMA, DMA and TMA but which resembles DMA or TMA in its various properties (e.g. Bergman et al., 2015). On the other hand, there are likely to be differences in the potentials of the three amines to enhance particle formation, causing uncertainties to the lumping approach. Systematic comparisons are needed to evaluate how to treat these species in atmospheric models and to assess what level of simplification is justifiable. In this work, we study the differences and similarities of MMA, DMA and TMA by modeling nanoparticle formation from sulfuric acid, water, and each of the three amines. We simulate molecular cluster concentrations and formation rates at boundary layer conditions with a dynamic cluster population model using quantum chemistry-based cluster evaporation rates, and study the dependence of particle formation rate on precursor vapor concentrations, temperature and relative humidity. The results suggest that for the three amines, there are differences in the nucleation mechanism and hygroscopicity of molecular clusters. However, for DMA and TMA, formation of nanometer-sized particles and its dependence on ambient conditions is roughly similar: both

  10. Monitoring Antarctic ice sheet surface melting with TIMESAT algorithm

    NASA Astrophysics Data System (ADS)

    Ye, Y.; Cheng, X.; Li, X.; Liang, L.

    2011-12-01

    Antarctic ice sheet contributes significantly to the global heat budget by controlling the exchange of heat, moisture, and momentum at the surface-atmosphere interface, which directly influence the global atmospheric circulation and climate change. Ice sheet melting will cause snow humidity increase, which will accelerate the disintegration and movement of ice sheet. As a result, detecting Antarctic ice sheet melting is essential for global climate change research. In the past decades, various methods have been proposed for extracting snowmelt information from multi-channel satellite passive microwave data. Some methods are based on brightness temperature values or a composite index of them, and others are based on edge detection. TIMESAT (Time-series of Satellite sensor data) is an algorithm for extracting seasonality information from time-series of satellite sensor data. With TIMESAT long-time series brightness temperature (SSM/I 19H) is simulated by Double Logistic function. Snow is classified to wet and dry snow with generalized Gaussian model. The results were compared with those from a wavelet algorithm. On this basis, Antarctic automatic weather station data were used for ground verification. It shows that this algorithm is effective in ice sheet melting detection. The spatial distribution of melting areas(Fig.1) shows that, the majority of melting areas are located on the edge of Antarctic ice shelf region. It is affected by land cover type, surface elevation and geographic location (latitude). In addition, the Antarctic ice sheet melting varies with seasons. It is particularly acute in summer, peaking at December and January, staying low in March. In summary, from 1988 to 2008, Ross Ice Shelf and Ronnie Ice Shelf have the greatest interannual variability in amount of melting, which largely determines the overall interannual variability in Antarctica. Other regions, especially Larsen Ice Shelf and Wilkins Ice Shelf, which is in the Antarctic Peninsula

  11. Seismic Strong Motion Array Project (SSMAP) to Record Future Large Earthquakes in the Nicoya Peninsula area, Costa Rica

    NASA Astrophysics Data System (ADS)

    Simila, G.; Lafromboise, E.; McNally, K.; Quintereo, R.; Segura, J.

    2007-12-01

    The seismic strong motion array project (SSMAP) for the Nicoya Peninsula in northwestern Costa Rica is composed of 10 - 13 sites including Geotech A900/A800 accelerographs (three-component), Ref-Teks (three- component velocity), and Kinemetric Episensors. The main objectives of the array are to: 1) record and locate strong subduction zone mainshocks [and foreshocks, "early aftershocks", and preshocks] in Nicoya Peninsula, at the entrance of the Nicoya Gulf, and in the Papagayo Gulf regions of Costa Rica, and 2) record and locate any moderate to strong upper plate earthquakes triggered by a large subduction zone earthquake in the above regions. Our digital accelerograph array has been deployed as part of our ongoing research on large earthquakes in conjunction with the Earthquake and Volcano Observatory (OVSICORI) at the Universidad Nacional in Costa Rica. The country wide seismographic network has been operating continuously since the 1980's, with the first earthquake bulletin published more than 20 years ago, in 1984. The recording of seismicity and strong motion data for large earthquakes along the Middle America Trench (MAT) has been a major research project priority over these years, and this network spans nearly half the time of a "repeat cycle" (~ 50 years) for large (Ms ~ 7.5- 7.7) earthquakes beneath the Nicoya Peninsula, with the last event in 1950. Our long time co- collaborators include the seismology group OVSICORI, with coordination for this project by Dr. Ronnie Quintero and Mr. Juan Segura. The major goal of our project is to contribute unique scientific information pertaining to a large subduction zone earthquake and its related seismic activity when the next large earthquake occurs in Nicoya. We are now collecting a database of strong motion records for moderate sized events to document this last stage prior to the next large earthquake. A recent event (08/18/06; M=4.3) located 20 km northwest of Samara was recorded by two stations (Playa Carrillo

  12. DLRS: gene tree evolution in light of a species tree.

    PubMed

    Sjöstrand, Joel; Sennblad, Bengt; Arvestad, Lars; Lagergren, Jens

    2012-11-15

    PrIME-DLRS (or colloquially: 'Delirious') is a phylogenetic software tool to simultaneously infer and reconcile a gene tree given a species tree. It accounts for duplication and loss events, a relaxed molecular clock and is intended for the study of homologous gene families, for example in a comparative genomics setting involving multiple species. PrIME-DLRS uses a Bayesian MCMC framework, where the input is a known species tree with divergence times and a multiple sequence alignment, and the output is a posterior distribution over gene trees and model parameters. PrIME-DLRS is available for Java SE 6+ under the New BSD License, and JAR files and source code can be downloaded from http://code.google.com/p/jprime/. There is also a slightly older C++ version available as a binary package for Ubuntu, with download instructions at http://prime.sbc.su.se. The C++ source code is available upon request. joel.sjostrand@scilifelab.se or jens.lagergren@scilifelab.se. PrIME-DLRS is based on a sound probabilistic model (Åkerborg et al., 2009) and has been thoroughly validated on synthetic and biological datasets (Supplementary Material online).

  13. General physiology, experimental psychology, and evolutionism. Unicellular organisms as objects of psychophysiological research, 1877-1918.

    PubMed

    Schloegel, Judy Johns; Schmidgen, Henning

    2002-12-01

    This essay aims to shed new light on the relations between physiology and psychology in the late nineteenth and early twentieth centuries by focusing on the use of unicellular organisms as research objects during that period. Within the frameworks of evolutionism and monism advocated by Ernst Haeckel, protozoa were perceived as objects situated at the borders between organism and cell and individual and society. Scholars such as Max Verworn, Alfred Binet, and Herbert Spencer Jennings were provoked by these organisms to undertake experimental investigations situated between general physiology and psychology that differed from the physiological psychology advocated by Wilhelm Wundt. Some of these investigations sought to locate psychological properties in the molecular structure of protoplasm; others stressed the existence of organic and psychological individuality in protozoa. In the following decades, leading philosophers such as Friedrich Nietzsche, Charles Sanders Peirce, and Henri Bergson, as well as psychological researchers like Sigmund Freud, integrated the results of these investigations into their reflections on such problems as the nature of the will, the structure of the ego, and the holistic nature of the reactions of organisms to their environment.

  14. Dietary whole grain–microbiota interactions: insights into mechanisms for human health.

    PubMed

    Keim, Nancy L; Martin, Roy J

    2014-09-01

    This article summarizes the presentations from the “Dietary Whole Grain–Microbiota Interactions: Insights into Mechanisms for Human Health” symposium held at the ASN Scientific Sessions and Annual Meeting at Experimental Biology 2014 in San Diego, CA, on 28 April 2014. The symposium focused on the interactive effects of whole grains and nondigestible carbohydrates with the gut microbiota with the goal of identifying the benefits of whole grains that are mediated through their effects on the gut microbiome. This theme was addressed by 4 speakers, each with their own unique perspective. Dr. Michael Lefevre reviewed the impact of whole grains on markers of subclinical inflammation, drawing examples from epidemiologic literature, clinical trials, and animal experiments. Dr. Knud Erik Bach Knudsen discussed data from studies he conducted to identify specific carbohydrates that enhance colonic butyrate production. Dr. Michael Keenan presented a chronology of his research program devoted to understanding the mechanisms underlying the metabolic effects of resistant starch, particularly high-amylose maize. Dr. Jens Walter emphasized that whole grains can impact gut microbial ecology by increasing microbial diversity and inducing compositional alterations, some of which are considered to have beneficial effects on the host.

  15. Current developments in clinical multiphoton tomography

    NASA Astrophysics Data System (ADS)

    König, Karsten; Weinigel, Martin; Breunig, Hans Georg; Gregory, Axel; Fischer, Peter; Kellner-Höfer, Marcel; Bückle, Rainer

    2010-02-01

    Two-photon microscopy has been introduced in 1990 [1]. 13 years later, CE-marked clinical multiphoton systems for 3D imaging of human skin with subcellular resolution have been launched by the JenLab company with the tomograph DermaInspectTM. In 2010, the second generation of clinical multiphoton tomographs was introduced. The novel mobile multiphoton tomograph MPTflexTM, equipped with a flexible articulated optical arm, provides an increased flexibility and accessibility especially for clinical and cosmetical examinations. The multiphoton excitation of fluorescent biomolecules like NAD(P)H, flavins, porphyrins, elastin, and melanin as well as the second harmonic generation of collagen is induced by picojoule femtosecond laser pulses from an tunable turn-key near infrared laser system. The ability for rapid highquality image acquisition, the user-friendly operation of the system, and the compact and flexible design qualifies this system to be used for melanoma detection, diagnostics of dermatological disorders, cosmetic research, and skin aging measurements as well as in situ drug monitoring and animal research. So far, more than 1,000 patients and volunteers have been investigated with the multiphoton tomographs in Europe, Asia, and Australia.

  16. A Multi-proxy Approach to Using Cave Sediment Carbon Isotopes for Late Holocene Paleoenvironmental Reconstruction in Florida

    NASA Astrophysics Data System (ADS)

    Polk, J. S.; van Beynen, P.

    2007-12-01

    Carbon isotopes from cave sediments collected from Jennings Cave in Marion County, Florida were analyzed using a multi-proxy approach. Fulvic acids (FAs), humic acids (HAs), black carbon, phytoliths, and bulk organic matter were extracted from the sediments for carbon isotope analysis to determine periods of vegetation change caused by climatic influences during the Late Holocene (~\\ 2,800 years BP). The carbon isotope record ranges from -35‰ to -14‰, exhibiting variability of ~\\ -21‰, within the different proxies, which indicates changes between C3 and C4 vegetation. This likely indicates changes between a sub-tropical forested environment and more arid, grassy plains conditions. These changes in plant assemblages were in response to changes in available water resources, with increased temperatures and evapotranspiration leading to arid conditions and a shift toward less C3 vegetation (increased C4 vegetation) during the MWP. The cave sediment fulvic acid cabon isotopes record agrees well with ä13C values from a speleothem collected nearby that covers the same time period. Prolonged migration of the NAO and ITCZ affects precipitation in Florida and likely caused vegetation changes during these climatic shifts.

  17. 'Remixing Rasmussen': The evolution of Accimaps within systemic accident analysis.

    PubMed

    Waterson, Patrick; Jenkins, Daniel P; Salmon, Paul M; Underwood, Peter

    2017-03-01

    Throughout Jens Rasmussen's career there has been a continued emphasis on the development of methods, techniques and tools for accident analysis and investigation. In this paper we focus on the evolution and development of one specific example, namely Accimaps and their use for accident analysis. We describe the origins of Accimaps followed by a review of 27 studies which have applied and adapted Accimaps over the period 2000-2015 to a range of domains and types of accident. Aside from demonstrating the versatility and popularity of the method, part of the motivation for the review of the use of Accimaps is to address the question of what constitutes a sound, usable, valid and reliable approach to systemic accident analysis. The findings from the review demonstrate continuity with the work carried out by Rasmussen, as well as significant variation (e.g., changes to the Accimap, used of additional theoretical and practice-oriented perspectives on safety). We conclude the paper with some speculations regarding future extension and adaptation of the Accimap approach including the possibility of using hybrid models for accident analysis. Copyright © 2016 Elsevier Ltd. All rights reserved.

  18. Cornea surgery with nanojoule femtosecond laser pulses

    NASA Astrophysics Data System (ADS)

    Koenig, Karsten; Wang, Bagui; Riemann, Iris; Kobow, Jens

    2005-04-01

    We report on a novel optical method for (i) flap-generation in LASIK procedures as well as (ii) for flap-free intrastromal refractive surgery based on nanojoule femtosecond laser pulses. The near infrared 200 fs pulses for multiphoton ablation have been provided by ultracompact turn-key MHz laser resonators. LASIK flaps and intracorneal cavities have been realized with high precision within living New Zealand rabbits using the system FemtoCutO (JenLab GmbH, Jena, Germany) at 800 nm laser wavelength. Using low-energy sub-2 nJ laser pulses, collateral damage due to photodisruptive and self-focusing effects was avoided. The laser ablation system consists of fast galvoscanners, focusing optics of high numerical aperture as well as a sensitive imaging system and provides also the possibility of 3D multiphoton imaging of fluorescent cellular organelles and SHG signals from collagen. Multiphoton tomography of the cornea was used to determine the exact intratissue beam position and to visualize intraocular post-laser effects. The wound healing process has been investigated up to 90 days after instrastromal laser ablation by histological analysis. Regeneration of damaged collagen structures and the migration of inflammation cells have been detected.

  19. Y-chromosome lineage determines cardiovascular organ T-cell infiltration in the stroke-prone spontaneously hypertensive rat.

    PubMed

    Khan, Shanzana I; Andrews, Karen L; Jackson, Kristy L; Memon, Basimah; Jefferis, Ann-Maree; Lee, Man K S; Diep, Henry; Wei, Zihui; Drummond, Grant R; Head, Geoffrey A; Jennings, Garry L; Murphy, Andrew J; Vinh, Antony; Sampson, Amanda K; Chin-Dusting, Jaye P F

    2018-05-01

    The essential role of the Y chromosome in male sex determination has largely overshadowed the possibility that it may exert other biologic roles. Here, we show that Y-chromosome lineage is a strong determinant of perivascular and renal T-cell infiltration in the stroke-prone spontaneously hypertensive rat, which, in turn, may influence vascular function and blood pressure (BP). We also show, for the first time to our knowledge, that augmented perivascular T-cell levels can directly instigate vascular dysfunction, and that the production of reactive oxygen species that stimulate cyclo-oxygenase underlies this. We thus provide strong evidence for the consideration of Y-chromosome lineage in the diagnosis and treatment of male hypertension, and point to the modulation of cardiovascular organ T-cell infiltration as a possible mechanism that underpins Y- chromosome regulation of BP.-Khan, S. I., Andrews, K. L., Jackson, K. L., Memon, B., Jefferis, A.-M., Lee, M. K. S., Diep, H., Wei, Z., Drummond, G. R., Head, G. A., Jennings, G. L., Murphy, A. J., Vinh, A., Sampson, A. K., Chin-Dusting, J. P. F. Y-chromosome lineage determines cardiovascular organ T-cell infiltration in the stroke-prone spontaneously hypertensive rat.

  20. Reduced Fatalism and Increased Prevention Behavior After Two High-Profile Lung Cancer Events

    PubMed Central

    PORTNOY, DAVID B.; LEACH, CORINNE R.; KAUFMAN, ANNETTE R.; MOSER, RICHARD P.; ALFANO, CATHERINE M.

    2015-01-01

    The positive impact of media coverage of high-profile cancer events on cancer prevention behaviors is well-established. However, less work has focused on potential adverse psychological reactions to such events, such as fatalism. Conducting 3 studies, the authors explored how the lung cancer death of Peter Jennings and diagnosis of Dana Reeve in 2005 related to fatalism. Analysis of a national media sample in Study 1 found that media coverage of these events often focused on reiterating the typical profile of those diagnosed with lung cancer; 38% of the media mentioned at least 1 known risk factor for lung cancer, most often smoking. Data from a nationally representative survey in Study 2 found that respondents reported lower lung cancer fatalism, after, compared with before, the events (OR = 0.16, 95% CI [0.03, 0.93]). A sustained increase in call volume to the national tobacco Quitline after these events was found in Study 3. These results suggest that there is a temporal association between high-profile cancer events, the subsequent media coverage, psychological outcomes, and cancer prevention behaviors. These results suggest that high-profile cancer events could be leveraged as an opportunity for large-scale public heath communication campaigns through the dissemination of cancer prevention messages and services. PMID:24274730

  1. Molecular modeling and in-silico engineering of Cardamom mosaic virus coat protein for the presentation of immunogenic epitopes of Leptospira LipL32.

    PubMed

    Kumar, Vikram; Damodharan, S; Pandaranayaka, Eswari P J; Madathiparambil, Madanan G; Tennyson, Jebasingh

    2016-01-01

    Expression of Cardamom mosaic virus (CdMV) coat protein (CP) in E. coli forms virus-like particles. In this study, the structure of CdMV CP was predicted and used as a platform to display epitopes of the most abundant surface-associated protein, LipL32 of Leptospira at C, N, and both the termini of CdMV CP. In silico, we have mapped sequential and conformational B-cell epitopes from the crystal structure of LipL32 of Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 using IEDB Elipro, ABCpred, BCPRED, and VaxiJen servers. Our results show that the epitopes displayed at the N-terminus of CdMV CP are promising vaccine candidates as compared to those displayed at the C-terminus or at both the termini. LipL32 epitopes, EP2, EP3, EP4, and EP6 are found to be promising B-cell epitopes for vaccine development. Based on the type of amino acids, length, surface accessibility, and docking energy with CdMV CP model, the order of antigenicity of the LipL32 epitopes was found to be EP4 > EP3 > EP2 > EP6.

  2. Curiosity ChemCam Finds High-Silica Mars Rocks

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Frydenvang, Jens

    A team of scientists, including one from Los Alamos National Laboratory, has found much higher concentrations of silica at some sites the Curiosity rover has investigated in the past seven months than anywhere else it has visited since landing on Mars 40 months ago. The first discovery was as Curiosity approached the area “Marias Pass,” where a lower geological unit contacts an overlying one. ChemCam, the rover’s laser-firing instrument for checking rock composition from a distance, detected bountiful silica in some targets the rover passed along the way to the contact zone. The ChemCam instrument was developed at Los Alamosmore » in partnership with the French IRAP laboratory in Toulouse and the French Space Agency. “The high silica was a surprise,” said Jens Frydenvang of Los Alamos National Laboratory and the University of Copenhagen, also a Curiosity science team member. “While we’re still working with multiple hypotheses on how the silica got so enriched, these hypotheses all require considerable water activity, and on Earth high silica deposits are often associated with environments that provide excellent support for microbial life. Because of this, the science team agreed to make a rare backtrack to investigate it more.”« less

  3. KSC-03PD-3145

    NASA Technical Reports Server (NTRS)

    2003-01-01

    KENNEDY SPACE CENTER, FLA. Officials of the NASA-Kennedy Space Center and the state of Florida pose for a group portrait at a dedication and ribbon-cutting ceremony for the Space Life Sciences Lab at the new lab. From left are Capt. Winston Scott, executive director of the Florida Space Authority; Dr. Robert J. Ferl, director of Space Agriculture Biotechnology Research and Education (SABRE), University of Florida; Charlie Quincy, chief of the Biological Sciences Office, Kennedy Space Center; Jose Perez-Morales, NASA Project Manager for the Space Life Sciences Lab; Jim Kennedy, director of the Kennedy Space Center; The Honorable Toni Jennings, lieutenant governor of the state of Florida; Frank T. Brogan, president of the Florida Atlantic University; and Dr. Samuel Durrance, executive director of the Florida Space Research Institute. Completed in August, the facility encompasses more than 100,000 square feet and was formerly known as the Space Experiment Research and Processing Laboratory or SERPL. The state, through the Florida Space Authority, built the research lab which is host to NASA, NASAs Life Sciences Services contractor Dynamac Corp., Bionetics Corp., and researchers from the University of Florida. Dynamac Corp. leases the facility. The Florida Space Research Institute is responsible for gaining additional tenants from outside the NASA community.

  4. California spotted owls: Chapter 5 in Managing Sierra Nevada forests

    USGS Publications Warehouse

    Roberts, Suzanne C.; Brooks, Matthew L.

    2012-01-01

    California spotted owls (Strix occidentalis occidentalis) are habitat specialists that are strongly associated with late-successional forests. For nesting and roosting, they require large trees and snags embedded in a stand with a complex forest structure (Blakesley et al. 2005, Gutiérrez et al. 1992, Verner et al. 1992b). In mixedconifer forests of the Sierra Nevada, California spotted owls typically nest and roost in stands with high canopy closure (≥75 percent) [Note: when citing studies, we use terminology consistent with Jennings et al. (1999), however, not all studies properly distinguish between canopy cover and closure and often use the terms interchangeably (see chapter 14 for clarification)] and an abundance of large trees (>24 in (60 cm) diameter at breast height [d.b.h.]) (Bias and Gutiérrez 1992, Gutiérrez et al. 1992, LaHaye et al. 1997, Moen and Gutiérrez 1997, Verner et al. 1992a). The California spotted owl guidelines (Verner et al. 1992b) effectively summarized much of the information about nesting and roosting habitat. Since that report, research on the California spotted owl has continued with much of the new information concentrated in five areas: population trends, barred owl (Strix varia) invasion, climate effects, foraging habitat, and owl response to fire.

  5. Reduced fatalism and increased prevention behavior after two high-profile lung cancer events.

    PubMed

    Portnoy, David B; Leach, Corinne R; Kaufman, Annette R; Moser, Richard P; Alfano, Catherine M

    2014-01-01

    The positive impact of media coverage of high-profile cancer events on cancer prevention behaviors is well-established. However, less work has focused on potential adverse psychological reactions to such events, such as fatalism. Conducting 3 studies, the authors explored how the lung cancer death of Peter Jennings and diagnosis of Dana Reeve in 2005 related to fatalism. Analysis of a national media sample in Study 1 found that media coverage of these events often focused on reiterating the typical profile of those diagnosed with lung cancer; 38% of the media mentioned at least 1 known risk factor for lung cancer, most often smoking. Data from a nationally representative survey in Study 2 found that respondents reported lower lung cancer fatalism, after, compared with before, the events (OR = 0.16, 95% CI [0.03, 0.93]). A sustained increase in call volume to the national tobacco Quitline after these events was found in Study 3. These results suggest that there is a temporal association between high-profile cancer events, the subsequent media coverage, psychological outcomes, and cancer prevention behaviors. These results suggest that high-profile cancer events could be leveraged as an opportunity for large-scale public heath communication campaigns through the dissemination of cancer prevention messages and services.

  6. Clinical studies of pigmented lesions in human skin by using a multiphoton tomograph

    NASA Astrophysics Data System (ADS)

    Balu, Mihaela; Kelly, Kristen M.; Zachary, Christopher B.; Harris, Ronald M.; Krasieva, Tatiana B.; König, Karsten; Tromberg, Bruce J.

    2013-02-01

    In vivo imaging of pigmented lesions in human skin was performed with a clinical multiphoton microscopy (MPM)-based tomograph (MPTflex, JenLab, Germany). Two-photon excited fluorescence was used for visualizing endogenous fluorophores such as NADH/FAD, keratin, melanin in the epidermal cells and elastin fibers in the dermis. Collagen fibers were imaged by second harmonic generation. Our study involved in vivo imaging of benign melanocytic nevi, atypical nevi and melanoma. The goal of this preliminary study was to identify in vivo the characteristic features and their frequency in pigmented lesions at different stages (benign, atypical and malignant) and to evaluate the ability of in vivo MPM to distinguish atypical nevi from melanoma. Comparison with histopathology was performed for the biopsied lesions. Benign melanocytic nevi were characterized by the presence of nevus cell nests at the epidermal-dermal junction. In atypical nevi, features such as lentiginous hyperplasia, acanthosis and architectural disorder were imaged. Cytological atypia was present in all the melanoma lesions imaged, showing the strongest correlation with malignancy. The MPM images demonstrated very good correlation with corresponding histological images, suggesting that MPM could be a promising tool for in vivo non-invasive pigmented lesion diagnosis, particularly distinguishing atypical nevi from melanoma.

  7. SAM Team Celebrates Landing

    NASA Image and Video Library

    2012-11-30

    Who Should Be TIME's Person of the Year 2012? - The Mars Rover! VOTE here: ti.me/YxJU1i Caption - SAM Team celebrates a picture perfect landing! Pictured from left to rights: Mehdi Benna, Laurie Leshin, Chris Webster, Will Brinckerhoff, Paul Mahaffy, Pan Conrad, Florence Tan, and Jen Eigenbrode. Credit: NASA ----- The Curiosity rover bristles with multiple cameras and instruments, including Goddard's Sample Analysis at Mars (SAM) instrument suite. By looking for evidence of water, carbon, and other important building blocks of life in the Martian soil and atmosphere, SAM will help discover whether Mars ever had the potential to support life. Curiosity was delivered to Gale crater, a 96-mile-wide crater that contains a record of environmental changes in its sedimentary rock, in August 2012. Related links: www.nasa.gov/mission_pages/msl/index.html science.gsfc.nasa.gov/699/marsSAM.shtml mars.jpl.nasa.gov/msl/ NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

  8. Seismic Strong Motion Array Project (SSMAP) to Record Future Large Earthquakes in the Nicoya Peninsula area, Costa Rica

    NASA Astrophysics Data System (ADS)

    Simila, G.; McNally, K.; Quintero, R.; Segura, J.

    2006-12-01

    The seismic strong motion array project (SSMAP) for the Nicoya Peninsula in northwestern Costa Rica is composed of 10 13 sites including Geotech A900/A800 accelerographs (three-component), Ref-Teks (three- component velocity), and Kinemetric Episensors. The main objectives of the array are to: 1) record and locate strong subduction zone mainshocks [and foreshocks, "early aftershocks", and preshocks] in Nicoya Peninsula, at the entrance of the Nicoya Gulf, and in the Papagayo Gulf regions of Costa Rica, and 2) record and locate any moderate to strong upper plate earthquakes triggered by a large subduction zone earthquake in the above regions. Our digital accelerograph array has been deployed as part of our ongoing research on large earthquakes in conjunction with the Earthquake and Volcano Observatory (OVSICORI) at the Universidad Nacional in Costa Rica. The country wide seismographic network has been operating continuously since the 1980's, with the first earthquake bulletin published more than 20 years ago, in 1984. The recording of seismicity and strong motion data for large earthquakes along the Middle America Trench (MAT) has been a major research project priority over these years, and this network spans nearly half the time of a "repeat cycle" (50 years) for large (Ms 7.5- 7.7) earthquakes beneath the Nicoya Peninsula, with the last event in 1950. Our long time co-collaborators include the seismology group OVSICORI, with coordination for this project by Dr. Ronnie Quintero and Mr. Juan Segura. Numerous international investigators are also studying this region with GPS and seismic stations (US, Japan, Germany, Switzerland, etc.). Also, there are various strong motion instruments operated by local engineers, for building purposes and mainly concentrated in the population centers of the Central Valley. The major goal of our project is to contribute unique scientific information pertaining to a large subduction zone earthquake and its related seismic activity when

  9. Cognitive Style and Mobile E-Learning in Emergent Otorhinolaryngology-Head and Neck Surgery Disorders for Millennial Undergraduate Medical Students: Randomized Controlled Trial.

    PubMed

    Lee, Li-Ang; Chao, Yi-Ping; Huang, Chung-Guei; Fang, Ji-Tseng; Wang, Shu-Ling; Chuang, Cheng-Keng; Kang, Chung-Jan; Hsin, Li-Jen; Lin, Wan-Ni; Fang, Tuan-Jen; Li, Hsueh-Yu

    2018-02-13

    -9 vs 6, IQR=4-7, P=.01) compared with the PPS group. Using Friedman's two-way nonparametric analysis of variance, cognitive styles (field-independent, field-intermediate, or field-dependent classification) and learning modules (IM or PPS) had significant effects on both knowledge gain (both adjusted P<.001) and satisfaction (both adjusted P<.001). Mobile e-learning is an effective modality to improve knowledge of emergent ORL-HNS in millennial undergraduate medical students. Our findings suggest the necessity of developing various modules for undergraduate medical students with different cognitive styles. Clinicaltrials.gov NCT02971735; https://clinicaltrials.gov/ct2/show/NCT02971735 (Archived by WebCite at http://www.webcitation.org/6waoOpCEV). ©Li-Ang Lee, Yi-Ping Chao, Chung-Guei Huang, Ji-Tseng Fang, Shu-Ling Wang, Cheng-Keng Chuang, Chung-Jan Kang, Li-Jen Hsin, Wan-Ni Lin, Tuan-Jen Fang, Hsueh-Yu Li. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 13.02.2018.

  10. Some aspects of water quality in a polluted lowland river in relation to the intracellular chemical levels in planktonic and epilithic diatoms.

    PubMed

    Tien, Chien-Jung

    2004-04-01

    Changes in elemental concentrations of diatoms and river water from the river Erh-Jen were determined using scanning electron microscopy energy-dispersive X-ray microanalysis and inductively coupled plasma mass spectrometry. Relatively large amounts of copper and lead found in both planktonic and epilithic diatoms implied these algae might play an important role in biogeochemical cycles and in the transfer of those elements to higher trophic levels in the aquatic environment. Changes in elemental concentrations within diatom cells were found to vary with other elements within cells and the same or different elements in water. Planktonic and epilithic cells showed different correlation patterns. For epilithic diatoms, negative correlations were found between concentrations of total phosphorus and phosphate in water and those of phosphorus within cells, and between concentrations of lead in water and in cells. Concentrations of chromium and mercury within planktonic cells and those of phosphorus, manganese and lead within epilithic ones were found to be easily influenced by other elements in river water, indicating appearance of the competitive manner on uptake of such elements by algal cells. Relatively high concentration factors (CFs) for cadmium, mercury and lead by diatoms in this study suggested they are good accumulators for these heavy metals. Significant negative corrections were found between the CFs of diatoms and the concentrations of elements in river water.

  11. Metabolic engineering and adaptive evolution for efficient production of D-lactic acid in Saccharomyces cerevisiae.

    PubMed

    Baek, Seung-Ho; Kwon, Eunice Y; Kim, Yong Hwan; Hahn, Ji-Sook

    2016-03-01

    There is an increasing demand for microbial production of lactic acid (LA) as a monomer of biodegradable poly lactic acid (PLA). Both optical isomers, D-LA and L-LA, are required to produce stereocomplex PLA with improved properties. In this study, we developed Saccharomyces cerevisiae strains for efficient production of D-LA. D-LA production was achieved by expressing highly stereospecific D-lactate dehydrogenase gene (ldhA, LEUM_1756) from Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 in S. cerevisiae lacking natural LA production activity. D-LA consumption after glucose depletion was inhibited by deleting DLD1 encoding D-lactate dehydrogenase and JEN1 encoding monocarboxylate transporter. In addition, ethanol production was reduced by deleting PDC1 and ADH1 genes encoding major pyruvate decarboxylase and alcohol dehydrogenase, respectively, and glycerol production was eliminated by deleting GPD1 and GPD2 genes encoding glycerol-3-phosphate dehydrogenase. LA tolerance of the engineered D-LA-producing strain was enhanced by adaptive evolution and overexpression of HAA1 encoding a transcriptional activator involved in weak acid stress response, resulting in effective D-LA production up to 48.9 g/L without neutralization. In a flask fed-batch fermentation under neutralizing condition, our evolved strain produced 112.0 g/L D-LA with a yield of 0.80 g/g glucose and a productivity of 2.2 g/(L · h).

  12. Curiosity ChemCam Finds High-Silica Mars Rocks

    ScienceCinema

    Frydenvang, Jens

    2018-01-16

    A team of scientists, including one from Los Alamos National Laboratory, has found much higher concentrations of silica at some sites the Curiosity rover has investigated in the past seven months than anywhere else it has visited since landing on Mars 40 months ago. The first discovery was as Curiosity approached the area “Marias Pass,” where a lower geological unit contacts an overlying one. ChemCam, the rover’s laser-firing instrument for checking rock composition from a distance, detected bountiful silica in some targets the rover passed along the way to the contact zone. The ChemCam instrument was developed at Los Alamos in partnership with the French IRAP laboratory in Toulouse and the French Space Agency. “The high silica was a surprise,” said Jens Frydenvang of Los Alamos National Laboratory and the University of Copenhagen, also a Curiosity science team member. “While we’re still working with multiple hypotheses on how the silica got so enriched, these hypotheses all require considerable water activity, and on Earth high silica deposits are often associated with environments that provide excellent support for microbial life. Because of this, the science team agreed to make a rare backtrack to investigate it more.”

  13. PREFACE: Fourth International Workshop on Inelastic Ion-Surface Collisions

    NASA Astrophysics Data System (ADS)

    Sigmund, Peter

    1983-01-01

    . All papers have undergone a normal, and occasionally extensive, refereeing procedure. In the midst of the editing process, I received the news that one of the invited speakers, Morton Traum of Bell Laboratories, had died at age 41 on 1 December, 1982 in Stoughton, Wisconsin. Mort had delivered a superb talk on Desorption and Sputtering by Electronic Processes and had been one of the most active participants and perhaps the most broadly oriented one of the workshop. His intense curiosity and serene charm, combined with a solid background in all parts of surface science, contributed stimulating ideas to most of the topics discussed. In preparing the workshop, I got much useful advice and constructive criticism from the members of the international committee. The assistance of the members of the local committee, Nils Andersen, Flemming Besenbacher, Jens Nørskov and Jens Onsgaard, as well as Erling Hartmann, Tove Nyberg and my wife Pia was instrumental at various stages before, during and after the workshop. Generous funding was received from the Office of Naval Research, the Danish Natural Science Research Council, NORDITA, the Nordic Accelerator Committee, the Research Foundation of Odense University and the Danish Provincial Bank. It is a pleasure to acknowledge the professional service of the Hindsgavl Conference Center and the smooth cooperation with Dr N R Nilsson, executive editor of Physica Scripta.

  14. COMMITTEES: Quark Matter 2008 Organising and International Advisory Committees

    NASA Astrophysics Data System (ADS)

    2008-10-01

    Organising Committee Madan M Aggarwal (Chandigarh) Jan-e Alam (Kolkata) Convener Arup Bandyopadhyay (Kolkata) Debades Bandyopadhyay (Kolkata) Rahul Basu (Chennai) Rakesh K Bhandari (Kolkata) Anju Bhasin (Jammu) Subhasis Chattopadhyay (Kolkata) Convener Sukalyan Chattopadhyay (Kolkata) Asis Chaudhuri (Kolkata) Premomoy Ghosh (Kolkata) Sanjay Ghosh (Kolkata) Sourendu Gupta (Mumbai) Muhammad Irfan (Aligarh) Durga P Mahapatra (Bhubaneswar) DAmruta Mishra (New Delhi) Ajit K Mohanty (Mumbai) Bedangadas Mohanty (Kolkata) Vaisali Naik (Kolkata) Tapan K Nayak (Kolkata) Convener Sudhir Raniwala (Jaipur) Sourav Sarkar (Kolkata) Bikash Sinha (Kolkata) Chair Dinesh Srivastava (Kolkata) Raghava Varma (Mumbai) Yogendra P Viyogi (Bhubaneswar)Co-chair International Advisory Committee R Aymar,Switzerland Jean Paul Blaizot, France Peter Braun Münzinger, Germany Igor M Dremin, Russia Kari Eskola, Finland Jens Jorgen Gaardhoje,Denmark Rajiv V Gavai, India Hans-Ake Gustaffson, Sweden Hans Gutbrod, Germany Miklos Gyulassy, USA Timothy Hallman, USA Hideki Hamagaki, Japan Tetsuo Hatsuda, Japan Huan-Zhong Huang, USA Barbara Jacak, USA Peter Jenni, Switzerland Taka Kajino, Japan Takeshi Kodama, Brazil T D Lee, USA Peter Levai, Hungary Luciano Maiani, Italy Larry McLerran, USA Berndt Müller, USA Guy Paic, Mexico Sibaji Raha, India Lodovico Riccati, Italy Hans Georg Ritter, USA Helmut Satz, Germany Jurgen Schukraft, Switzerland Yves Schutz, France Edward V Shuryak, USA Johanna Stachel, Germany Horst Stöcker, Germany Itzhak Tserruya, Israel Xin-Nian Wang, USA Bolek Wyslouch, USA Glenn R Young, USA William A Zajc, USA Wen-Long Zhan, China

  15. Ensuring due process in the IACUC and animal welfare setting: considerations in developing noncompliance policies and procedures for institutional animal care and use committees and institutional officials.

    PubMed

    Hansen, Barbara C; Gografe, Sylvia; Pritt, Stacy; Jen, Kai-Lin Catherine; McWhirter, Camille A; Barman, Susan M; Comuzzie, Anthony; Greene, Molly; McNulty, Justin A; Michele, Daniel Eugene; Moaddab, Naz; Nelson, Randall J; Norris, Karen; Uray, Karen D; Banks, Ron; Westlund, Karin N; Yates, Bill J; Silverman, Jerald; Hansen, Kenneth D; Redman, Barbara

    2017-10-01

    Every institution that is involved in research with animals is expected to have in place policies and procedures for the management of allegations of noncompliance with the Animal Welfare Act and the U.S. Public Health Service Policy on the Humane Care and Use of Laboratory Animals. We present here a model set of recommendations for institutional animal care and use committees and institutional officials to ensure appropriate consideration of allegations of noncompliance with federal Animal Welfare Act regulations that carry a significant risk or specific threat to animal welfare. This guidance has 3 overarching aims: 1 ) protecting the welfare of research animals; 2 ) according fair treatment and due process to an individual accused of noncompliance; and 3 ) ensuring compliance with federal regulations. Through this guidance, the present work seeks to advance the cause of scientific integrity, animal welfare, and the public trust while recognizing and supporting the critical importance of animal research for the betterment of the health of both humans and animals.-Hansen, B. C., Gografe, S., Pritt, S., Jen, K.-L. C., McWhirter, C. A., Barman, S. M., Comuzzie, A., Greene, M., McNulty, J. A., Michele, D. E., Moaddab, N., Nelson, R. J., Norris, K., Uray, K. D., Banks, R., Westlund, K. N., Yates, B. J., Silverman, J., Hansen, K. D., Redman, B. Ensuring due process in the IACUC and animal welfare setting: considerations in developing noncompliance policies and procedures for institutional animal care and use committees and institutional officials. © FASEB.

  16. [Reference values for the blood coagulation tests in Mexico: usefulness of the pooled plasma from blood donors].

    PubMed

    Calzada-Contreras, Adriana; Moreno-Hernández, Manuel; Castillo-Torres, Noemi Patricia; Souto-Rosillo, Guadalupe; Hernández-Juárez, Jesús; Ricardo-Moreno, María Tania; Sánchez-Fernández, Maria Guadalupe de Jesús; García-González, América; Majluf-Cruz, Abraham

    2012-01-01

    The blood coagulation system maintains the blood in a liquid state and bleeding and thrombosis are the manifestations of its malfunction. Blood coagulation laboratory evaluates the physiology of this system. To establish both, the reference values for several tests performed at the blood coagulation laboratory as well as the utility of the pooled plasma to perform these assays. MATERIAL AND: In this descriptive, cross-sectional, randomized study, we collected plasma from Mexican Mestizos. Each pooled plasma was prepared with the plasma from at least 20 blood donors. We performed screening and special tests and the Levey-Jennings graphs were built and interpreted after each pass. Results of the tests were analyzed and their distribution was established using the Kolmogorov-Smirnov test. To establish the reference values we used 95% confidence intervals. We collected 72 pooled plasmas. The distribution for PT, APTT, and TT tests was abnormal. Although the PT test showed a bimodal distribution it was normal for factor VII. The reference values for the hemostatic, anticoagulant, and fibrinolytic factors were different from those suggested by the manufacturers. We established the reference values for the blood coagulation tests in the adult Mexican population. We have shown that the pooled plasma must be used for the screening tests. We suggest that each clinical laboratory should establish its own reference values (at least for the screening tests). To reach this objective, we encourage the use of the pooled plasma.

  17. In vivo multiphoton tomography and fluorescence lifetime imaging of human brain tumor tissue.

    PubMed

    Kantelhardt, Sven R; Kalasauskas, Darius; König, Karsten; Kim, Ella; Weinigel, Martin; Uchugonova, Aisada; Giese, Alf

    2016-05-01

    High resolution multiphoton tomography and fluorescence lifetime imaging differentiates glioma from adjacent brain in native tissue samples ex vivo. Presently, multiphoton tomography is applied in clinical dermatology and experimentally. We here present the first application of multiphoton and fluorescence lifetime imaging for in vivo imaging on humans during a neurosurgical procedure. We used a MPTflex™ Multiphoton Laser Tomograph (JenLab, Germany). We examined cultured glioma cells in an orthotopic mouse tumor model and native human tissue samples. Finally the multiphoton tomograph was applied to provide optical biopsies during resection of a clinical case of glioblastoma. All tissues imaged by multiphoton tomography were sampled and processed for conventional histopathology. The multiphoton tomograph allowed fluorescence intensity- and fluorescence lifetime imaging with submicron spatial resolution and 200 picosecond temporal resolution. Morphological fluorescence intensity imaging and fluorescence lifetime imaging of tumor-bearing mouse brains and native human tissue samples clearly differentiated tumor and adjacent brain tissue. Intraoperative imaging was found to be technically feasible. Intraoperative image quality was comparable to ex vivo examinations. To our knowledge we here present the first intraoperative application of high resolution multiphoton tomography and fluorescence lifetime imaging of human brain tumors in situ. It allowed in vivo identification and determination of cell density of tumor tissue on a cellular and subcellular level within seconds. The technology shows the potential of rapid intraoperative identification of native glioma tissue without need for tissue processing or staining.

  18. One-stage Revision ACL reconstruction with hamstring autograft results in satisfactory outcome

    PubMed Central

    Kejriwal, Ritwik; Buelow, Jens

    2017-01-01

    Objectives: Revision anterior cruciate ligament (ACL) reconstruction is associated with poorer outcomes and higher rerupture rates when compared to primary ACL reconstruction. There is also a significant heterogeneity in surgical technique, number of stages, and graft options. We report a large single surgeon case series with hamstring autograft as a graft option. Methods: Observational series of revision ACL reconstructions performed by the senior author between 2005 and 2015 was carried out. Chart reviews and clinic follow-ups were performed with the following recorded – re-rupture rate, radiographic grading of osteoarthritis, KT-1000 arthrometer test, IKDC outcome scores and knee range of motion. All patients underwent single bundle four-strand hamstring autograft performed in one stage with use of new tunnels in majority of the cases. Results: 66 patients underwent hamstring autograft one-stage revision ACL reconstruction by Dr Jens Buelow. Chart review was carried out on all patients, and 26 (39%) were followed up in clinic and/or by phone with a mean follow up of 4.7 years. Outcomes included re-rupture rate of 4.5%, reoperation rate of 12%, mean visual analogue scale score of 7.6, mean side-to-side difference of 2.6 mm for KT-1000 arthrometer test, and mean IKDC score of 79. Of the 17 patients with radiographs, 40% had moderate osteoarthritis (grade 2 or 3) at follow-up. Conclusion: Revision ACL reconstruction can result in a satisfactory outcome when performed with a hamstring autograft in one stage.

  19. Cell mediated immunity cross-reactions of mycobacteria: polymorphism of target bacterial antigens.

    PubMed Central

    Kulkarni, S; Hattikudur, S; Kamat, R S

    1986-01-01

    Swiss white mice were immunized with different mycobacteria and delayed type hypersensitivity (DTH) responses were studied by the foot-pad swelling technique of Gray and Jennings (1955). Extensive cross-reactions in DTH, outside the limits of Runyon's groups were observed. As a general trend slow growing mycobacteria showed greater cross-reactivity with slow growers than with rapid growers and vice versa. The implied cross-protective significance of DTH cross-reactions was further confirmed by demonstration of the ability of DTH cross-reacting sonicates to generate activated macrophages in M. avium immunized mice. An antiserum was raised against the earlier reported DTH eliciting antigen of M. tuberculosis H37Rv (DTH-H37Rv). The sero-reactivity of anti-DTH-H37Rv against the sonicates of different mycobacteria was studied with the objective of investigating the molecular basis of DTH cross-reactivity. Immunoprecipitation reactions of different mycobacterial sonicates with anti-DTH-H37Rv showed that the antigen was shared by all the mycobacteria tested irrespective of their cross-reactivity in a DTH response. All of the slow growers showed reactions of total identity with DTH-H37Rv. However with rapid growers DTH-H37Rv showed only a partial identity. From these data it was concluded that an antigen participating in DTH response is shared by all mycobacteria and that it is polymorphous, having genus specific and group specific (as slow and rapid grower groups) determinants. Images Fig. 2 PMID:3082545

  20. Mobile Geochemistry Instrument Package Facility (MGIPF) for In Situ Mineralogical and Chemical Analysis of Planetary Surface Material

    NASA Astrophysics Data System (ADS)

    Klingelhöfer, G.; Romstedt, J.; Henkel, H.; Michaelis, H.; Brückner, J.; D'Uston, C.

    A first order requirement for any spacecraft mission to land on a solid planetary or moon surface is instrumentation for in-situ mineralogical and chemical analysis 2 Such analysis provide data needed for primary classification and characterization of surface materials present We will discuss a mobile instrument package we have developed for in-situ investigations under harsh environmental conditions like on Mercury or Mars This Geochemistry Instrument Package Facility is a compact box also called payload cab containing three small advanced geochemistry mineralogy instruments the chemical spectrometer APXS the mineralogical M o ssbauer spectrometer MIMOS II 3 and a textural imager close-up camera The payload cab is equipped with two actuating arms with two degrees of freedom permitting precision placement of all instruments at a chosen sample This payload cab is the central part of the small rover Nanokhod which has the size of a shoebox 1 The Nanokhod rover is a tethered system with a typical operational range of sim 100 m Of course the payload cab itself can be attached by means of its arms to any deployment device of any other rover or deployment device 1 Andre Schiele Jens Romstedt Chris Lee Sabine Klinkner Rudi Rieder Ralf Gellert G o star Klingelh o fer Bodo Bernhardt Harald Michaelis The new NANOKHOD Engineeering model for extreme cold environments 8th International symposium on Artificial Intelligence Robotics and Automation in Space 5 - 9 September 2005

  1. Imaging bio-distribution of a topically applied dermatological cream on minipig skin using fluorescence lifetime imaging microscopy (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Alex, Aneesh; Chaney, Eric J.; Criley, Jennifer M.; Spillman, Darold R.; Hutchison, Phaedra B.; Li, Joanne; Marjanovic, Marina; Frey, Steve; Cook, Steven; Boppart, Stephen A.; Arp, Zane A.

    2017-02-01

    Currently there is a lack of in vivo techniques to evaluate the spatial bio-distribution of dermal drugs over time without the need to take multiple serial biopsies. To address this gap, we investigated the use of multi-photon optical imaging methods to non-invasively track drug distribution on miniature pig (Species: Sus scrofa, Strain: Göttingen) skin in vivo. Minipig skin is the standard comparative research model to human skin, and is anatomically and functionally similar. We employed fluorescence lifetime imaging microscopy (FLIM) to visualize the spatial distribution and residency time of a topically applied experimental dermatological cream. This was made possible by the endogenous fluorescent optical properties of the experimental drug (fluorescence lifetime > 3000 ps). Two different drug formulations were applied on 2 minipigs for 7 consecutive days, with the control creams applied on the contralateral side, followed by 7 days of post-application monitoring using a multi-modal optical imaging system (MPTflex-CARS, JenLab, Germany). FLIM images were obtained from the treated regions 24 hr post-application from day 1 to day 14 that allowed visualization of cellular and sub-cellular features associated with different dermal layers non-invasively to a depth of 200 µm. Five punch biopsies per animal were obtained from the corresponding treated regions between days 8 and 14 for bioanalytical analysis and comparison with results obtained using FLIM. In conclusion, utilization of non-invasive optical biopsy methods for dermal drug evaluation can provide true longitudinal monitoring of drug spatial distribution, remove sampling limitations, and be more time-efficient compared to traditional methods.

  2. The mechanistic basis for psoriasis immunopathogenesis: translating genotype to phenotype. Report of a workshop, Venice, 2012.

    PubMed

    Bachelez, H; Viguier, M; Tebbey, P W; Lowes, M; Suárez-Fariñas, M; Costanzo, A; Nestle, F O

    2013-08-01

    The International Psoriasis Council, a global nonprofit organization dedicated to advancing psoriasis research and treatment, led an initiative to better define the pathogenic mechanisms that constitute psoriasis. In September 2012, a workshop was held at the 42nd Annual European Society for Dermatological Research in Venice, Italy. By assembling a panel of global dermatology and immunology experts, the objective was to evaluate the current status of the science explaining the mechanism of disease in psoriasis, e.g. dysregulation of the skin immune system and perturbations of epidermal homeostasis. The workshop consisted of four oral presentations, which addressed key topics in psoriasis, delivered by Hervé Bachelez (Paris, France), Antonio Costanzo (Rome, Italy), Michelle Lowes (New York, NY, U.S.A.) and Frank Nestle (London, U.K.). A global expert panel was assembled to stimulate dialogue and debate: Kevin Cooper (Cleveland, OH, U.S.A.), Michel Gilliet (Lausanne, Switzerland), Joerg Prinz (Munich, Germany), Martin Röcken (Tubingen, Germany), Jens Schroeder (Kiel, Germany), Manuelle Viguier (Paris, France), Mayte Suárez-Fariñas (New York, NY, U.S.A.) and Cristina Zielinski (Berlin, Germany). Collectively, the presentations demonstrated the significant advances in understanding immune regulation that have occurred over the past decade by virtue of the study of psoriasis subtypes, phenotypic manifestations and genetic associations. Elucidating the pathogenic and genetic basis of psoriasis holds the promise of a complete understanding of disease mechanisms, predictors of treatment response, novel drug development strategies and customized therapeutic regimens for the individual patient. © 2013 The Authors BJD © 2013 British Association of Dermatologists.

  3. Ethology and the origins of behavioral endocrinology.

    PubMed

    Marler, Peter

    2005-04-01

    The neurosciences embrace many disciplines, some long established, others of more recent origin. Behavioral endocrinology has only recently been fully acknowledged as a branch of neuroscience, distinctive for the determination of some of its exponents to remain integrative in the face of the many pressures towards reductionism that so dominate modern biology. One of its most characteristic features is a commitment to research at the whole-animal level on the physiological basis of complex behaviors, with a particular but by no means exclusive focus on reproductive behavior in all its aspects. The search for rigorously defined principles of behavioral organization that apply across species and the hormonal and neural mechanisms that sustain them underlies much of the research. Their aims are much like those put forth in the classical ethology of Lorenz and Tinbergen, one of the roots from which behavioral endocrinology has sprung. But there are others that can be traced back a century or more. Antecedents can be found in the work of such pioneers as Jakob von Uexküll, Jacques Loeb, Herbert Spencer Jennings, and particularly Charles Otis Whitman who launched a tradition that culminated in the classical contributions of Robert Hinde and Daniel Lehrman. William C. Young was another pioneer. His studies revolutionized thinking about the physiological mechanisms by which hormones influence behavior. An earlier potent influence was Karl Lashley who helped to shape the career of Frank Ambrose Beach who, more than anyone, has played a leading role in launching this new field.

  4. Time is muscle: translation into practice.

    PubMed

    Antman, Elliott M

    2008-10-07

    In the future, advances in the care of patients with ST-segment elevation myocardial infarction (STEMI) will not come from the analysis of trials that do not reflect current practice in an effort to rationalize extending the percutaneous coronary intervention (PCI)-related delay time. We must move beyond such arguments and find ways to shorten total ischemic time. With the launching of the American College of Cardiology's D2B Alliance and the American Heart Association's Mission: Lifeline programs, the focus is now on systems improvement for reperfusion in patients with STEMI. The D2B Alliance was developed to focus on improvement in door-to-balloon times for patients with STEMI who are undergoing primary PCI. The American Heart Association Mission: Lifeline program is a broad, comprehensive national initiative to improve the quality of care and outcomes of patients with STEMI by improving health care system readiness and response to STEMI. Improvements in access to timely care for patients with STEMI will require a multifaceted approach involving patient education, improvements in the Emergency Medical Services and emergency department components of care, the establishment of networks of STEMI-referral hospitals (not PCI capable) and STEMI-receiving hospitals (PCI capable), as well as coordinated advocacy efforts to work with payers and policy makers to implement a much-needed health care system redesign. By focusing now on system efforts for improvements in timely care for STEMI, we will complete the cycle of research initiated by Reimer and Jennings 30 years ago. Time is muscle ... we must translate that into practice.

  5. LISA 8 Science Organizing Committee and Local Organizing Committee LISA 8 Science Organizing Committee and Local Organizing Committee

    NASA Astrophysics Data System (ADS)

    2011-05-01

    Science Organising Committee (SOC) Tom Abel, Stanford University Odylio Aguiar, Instituto Nacional de Pesquisas Espaciais Tal Alexander, Wizemann Institute Peter Bender, University of Colorado Pierre Binetruy, APC - College de France Sasha Buchman, Stanford University Robert Byer, Stanford University Manuela Campanelli, University of Texas Joan Centrella, NASA/Goddard Massimo Cerdonio, University of Padova Eugenio Coccia, University of Roma-2 Neil Cornish, Montana State University Michael Cruise, University of Birmingham Curt Cutler, NASA/JPL Karsten Danzmann, University of Hannover Sam Finn, Penn State University Jens Gundlach, NPL Gerhard Heinzel, Max-Planck-Institut fuer Gravitationsphysik Craig Hogan, University of Washington Jim Hough, University of Glasgow Scott Hughes, MIT Oliver Jennrich, ESTEC Philippe Jetzer, University Zurich Seiji Kawamura, National Observatory, Japan Alberto Lobo, ICE-CSIC and IEEC Avi Loeb, Harvard University Piero Madau, Lick Observatory Yannick Mellier, IAP, Paris Peter Michelson, Stanford University Guido Mueller, University of Florida Sterl Phinney, Caltech Tom Prince, NASA/JPL Doug Richstone, University of Michigan Bernard Schutz, AEI Potsdam Tuck Stebbins, NASA/Goddard Tim Sumner, Imperial College, London Ke-Xun Sun, Stanford University Kip Thorne, Caltech Michele Vallisneri, NASA/JPL Alberto Vecchio, University of Birmingham Jean-Yves Vinet, OCA, Nice Stefano Vitale, University of Trento Rai Weiss, MIT Nick White, NASA/Goddard Local Organising Committee (LOC) Sasha Buchman (Stanford University) Robert Byer (Stanford University) Sara Charbonneau-Lefort (Stanford University) Nancy Christianson (Stanford University) John Conklin (Stanford University) Dan DeBra (Stanford University) Jan Goebel (Stanford University) Vivian Drew (Stanford University) Ke-Xun Sun (Stanford University) Lucy Zhou (Stanford University) Andrea Zoellner (Stanford University)

  6. Fine mapping and identification of a candidate gene for the barley Un8 true loose smut resistance gene.

    PubMed

    Zang, Wen; Eckstein, Peter E; Colin, Mark; Voth, Doug; Himmelbach, Axel; Beier, Sebastian; Stein, Nils; Scoles, Graham J; Beattie, Aaron D

    2015-07-01

    The candidate gene for the barley Un8 true loose smut resistance gene encodes a deduced protein containing two tandem protein kinase domains. In North America, durable resistance against all known isolates of barley true loose smut, caused by the basidiomycete pathogen Ustilago nuda (Jens.) Rostr. (U. nuda), is under the control of the Un8 resistance gene. Previous genetic studies mapped Un8 to the long arm of chromosome 5 (1HL). Here, a population of 4625 lines segregating for Un8 was used to delimit the Un8 gene to a 0.108 cM interval on chromosome arm 1HL, and assign it to fingerprinted contig 546 of the barley physical map. The minimal tilling path was identified for the Un8 locus using two flanking markers and consisted of two overlapping bacterial artificial chromosomes. One gene located close to a marker co-segregating with Un8 showed high sequence identity to a disease resistance gene containing two kinase domains. Sequence of the candidate gene from the parents of the segregating population, and in an additional 19 barley lines representing a broader spectrum of diversity, showed there was no intron in alleles present in either resistant or susceptible lines, and fifteen amino acid variations unique to the deduced protein sequence in resistant lines differentiated it from the deduced protein sequences in susceptible lines. Some of these variations were present within putative functional domains which may cause a loss of function in the deduced protein sequences within susceptible lines.

  7. Implementing self sustained quality control procedures in a clinical laboratory.

    PubMed

    Khatri, Roshan; K C, Sanjay; Shrestha, Prabodh; Sinha, J N

    2013-01-01

    Quality control is an essential component in every clinical laboratory which maintains the excellence of laboratory standards, supplementing to proper disease diagnosis, patient care and resulting in overall strengthening of health care system. Numerous quality control schemes are available, with combinations of procedures, most of which are tedious, time consuming and can be "too technical" whereas commercially available quality control materials can be expensive especially for laboratories in developing nations like Nepal. Here, we present a procedure performed at our centre with self prepared control serum and use of simple statistical tools for quality assurance. The pooled serum was prepared as per guidelines for preparation of stabilized liquid quality control serum from human sera. Internal Quality Assessment was performed on this sample, on a daily basis which included measurement of 12 routine biochemical parameters. The results were plotted on Levey-Jennings charts and analysed with quality control rules, for a period of one month. The mean levels of biochemical analytes in self prepared control serum were within normal physiological range. This serum was evaluated every day along with patients' samples. The results obtained were plotted on control charts and analysed using common quality control rules to identify possible systematic and random errors. Immediate mitigation measures were taken and the dispatch of erroneous reports was avoided. In this study we try to highlight on a simple internal quality control procedure which can be performed by laboratories, with minimum technology, expenditure, and expertise and improve reliability and validity of the test reports.

  8. COMMITTEES: LISA 7 Science Organizing Committee and Local Organizing Committee LISA 7 Science Organizing Committee and Local Organizing Committee

    NASA Astrophysics Data System (ADS)

    2009-05-01

    Science Organising Committee (SOC) Pierre Binetruy, APC - College de France Massimo Cerdonio, University of Padova Karsten Danzmann, AEI/University of Hannover Mike Cruise, University of Birmingham Jim Hough, University of Glasgow Oliver Jennrich, ESTEC Philippe Jetzer, University Zurich Alberto Lobo (Chair), ICE-CSIC and IEEC Yannick Mellier, IAP, Paris Bernard Schutz, AEI Potsdam Tim Sumner, Imperial College, London Jean-Yves Vinet, OCA, Nice Stefano Vitale, University of Trento Peter Bender, University of Colorado Sasha Buchman, Stanford University Joan Centrella, NASA/Goddard Neil Cornish, Montana State University Curt Cutler, NASA/JPL Sam Finn, Penn State University Jens Gundlach, NPL Craig Hogan, University of Washington Scott Hughes, MIT Piero Madau, Lick Observatory Tom Prince, NASA/JPL Sterl Phinney, Caltech Doug Richstone, University of Michigan Tuck Stebbins, NASA/Goddard Kip Thorne, Caltech Roger Blandford, Stanford University Eugenio Coccia, University of Roma-2 Carlos F Sopuerta,ICE-CSIC and IEEC Enrique Garcia-Berro, Universitat Politècnica de Catalunya, Barcelona Seiji Kawamura, National Observatory, Japan Jay Marx, LIGO Laboratory Stephen Merkowitz, NASA/Goddard Benoit Mours, Laboratoire d'Annec Gijs Nelemans, IMAPP, Nijmegen Enric Verdaguer, University of Barcelona Clifford M Will, Washington University, St Louis Local Organising Committee (LOC) Anna Bertolín (IEEC) Priscilla Cañizares (ICE-CSIC and IEEC) Carlos F Sopuerta (ICE-CSIC and IEEC) Ivan Lloro (ICE-CSIC and IEEC),Chair Alberto Lobo (ICE-CSIC and IEEC) Nacho Mateos (ICE-CSIC and IEEC) Pilar Montes (IEEC) Miquel Nofrarias (IEEC) Juan Ramos-Castro (Universitat Politècnica de Catalunya) Josep Sanjuán (IEEC)

  9. Along the Rainfall-Runoff Chain: From Scaling of Greatest Point Rainfall to Global Change Attribution

    NASA Astrophysics Data System (ADS)

    Fraedrich, K.

    2014-12-01

    Processes along the continental rainfall-runoff chain cover a wide range of time and space scales which are presented here combining observations (ranging from minutes to decades) and minimalist concepts. (i) Rainfall, which can be simulated by a censored first-order autoregressive process (vertical moisture fluxes), exhibits 1/f-spectra if presented as binary events (tropics), while extrema world wide increase with duration according to Jennings' scaling law. (ii) Runoff volatility (Yangtze) shows data collapse which, linked to an intra-annual 1/f-spectrum, is represented by a single function not unlike physical systems at criticality and the short and long return times of extremes are Weibull-distributed. Atmospheric and soil moisture variabilities are also discussed. (iii) Soil moisture (in a bucket), whose variability is interpreted by a biased coinflip Ansatz for rainfall events, adds an equation of state to energy and water flux balances comprising Budyko's frame work for quasi-stationary watershed analysis. Eco-hydrologic state space presentations in terms of surface flux ratios of energy excess (loss by sensible heat over supply by net radiation) versus water excess (loss by discharge over gain by precipitation) allow attributions of state change to external (or climate) and internal (or anthropogenic) causes. Including the vegetation-greenness index (NDVI) as an active tracer extends the eco-hydrologic state space analysis to supplement the common geographical presentations. Two examples demonstrate the approach combining ERA and MODIS data sets: (a) global geobotanic classification by combining first and second moments of the dryness ratio (net radiation over precipitation) and (b) regional attributions (Tibetan Plateau) of vegetation changes.

  10. Which resilience of the continental rainfall-runoff chain?

    NASA Astrophysics Data System (ADS)

    Fraedrich, Klaus

    2015-04-01

    Processes along the continental rainfall-runoff chain are extremely variable over a wide range of time and space scales. A key societal question is the multiscale resilience of this chain. We argue that the adequate framework to tackle this question can be obtained by combining observations (ranging from minutes to decades) and minimalist concepts: (i) Rainfall exhibits 1/f-spectra if presented as binary events (tropics) and extrema world wide increase with duration according to Jennings' scaling law as simulated by a censored first-order autoregressive process representing vertical moisture fluxes. (ii) Runoff volatility (Yangtze) shows data collapse which, linked to an intra-annual 1/f-spectrum, is represented by a single function (Gumbel) not unlike physical systems at criticality, while short and long return times of extremes are Weibull-distributed. (iii) Soil moisture, interpreted by a biased coinflip Ansatz for rainfall events, provides an equation of state to the surface energy and water flux balances comprising Budyko's framework for quasi-stationary watershed analysis. (iv) Vegetation-greenness (NDVI), included as an active tracer extends Budyko's eco-hydrologic state space analysis, supplements the common geographical presentations, and it may be linked to a minimalist biodiversity concept. (v) Finally, attributions of change to external (or climate) and internal (or anthropogenic) causes are determined by eco-hydrologic state space trajectories using surface flux ratios of energy excess (loss by sensible heat over supply by net radiation) versus water excess (loss by discharge over gain by precipitation). Risk-estimates (by GCM-emulators) and possible policy advice mechanisms enter the outlook.

  11. Effectiveness of an Internet- and App-Based Intervention for College Students With Elevated Stress: Randomized Controlled Trial.

    PubMed

    Harrer, Mathias; Adam, Sophia Helen; Fleischmann, Rebecca Jessica; Baumeister, Harald; Auerbach, Randy; Bruffaerts, Ronny; Cuijpers, Pim; Kessler, Ronald C; Berking, Matthias; Lehr, Dirk; Ebert, David Daniel

    2018-04-23

    depression. Internet- and mobile-based interventions could be an effective and cost-effective approach to reduce consequences of college-related stress and might potentially attract students with clinically relevant depression who would not otherwise seek help. German Clinical Trial Register DRKS00010212; http://www.drks.de/drks_web/navigate.do? navigationId=trial.HTML&TRIAL_ID=DRKS00010212 (Archived by WebCite at http://www.webcitation.org/6w55Ewhjd). ©Mathias Harrer, Sophia Helen Adam, Rebecca Jessica Fleischmann, Harald Baumeister, Randy Auerbach, Ronny Bruffaerts, Pim Cuijpers, Ronald C Kessler, Matthias Berking, Dirk Lehr, David Daniel Ebert. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 23.04.2018.

  12. Looking for a Symphony: A Sort of Essay with a Perspective on Activity Theories and the Ontology of Psychology: Learning from Danish and Russian Experiences by Jens Mammen & Irina Mironenko.

    PubMed

    Neumann, Asger

    2016-06-01

    As a perspective on Mammen and Miroenkos the article is reflecting on the possibility of Activity Theory being a foundation on which Psychology could be integrated. Mammen and Miroenkos point that directed activity not only is towards objects "defined as a sum of qualities, but by individual reference" is a starting point. As a specific example the phenomenon Love, as "significant object relations", is related to the concept "choice categories". It is stated that relations of affection and love can't be understood independent of history of common activity, and that this makes the concept "choice categories" central in a psychological understanding of what love is.

  13. Atrial Fibrillation Screening in Nonmetropolitan Areas Using a Telehealth Surveillance System With an Embedded Cloud-Computing Algorithm: Prospective Pilot Study.

    PubMed

    Chen, Ying-Hsien; Hung, Chi-Sheng; Huang, Ching-Chang; Hung, Yu-Chien; Hwang, Juey-Jen; Ho, Yi-Lwun

    2017-09-26

    Atrial fibrillation (AF) is a common form of arrhythmia that is associated with increased risk of stroke and mortality. Detecting AF before the first complication occurs is a recognized priority. No previous studies have examined the feasibility of undertaking AF screening using a telehealth surveillance system with an embedded cloud-computing algorithm; we address this issue in this study. The objective of this study was to evaluate the feasibility of AF screening in nonmetropolitan areas using a telehealth surveillance system with an embedded cloud-computing algorithm. We conducted a prospective AF screening study in a nonmetropolitan area using a single-lead electrocardiogram (ECG) recorder. All ECG measurements were reviewed on the telehealth surveillance system and interpreted by the cloud-computing algorithm and a cardiologist. The process of AF screening was evaluated with a satisfaction questionnaire. Between March 11, 2016 and August 31, 2016, 967 ECGs were recorded from 922 residents in nonmetropolitan areas. A total of 22 (2.4%, 22/922) residents with AF were identified by the physician's ECG interpretation, and only 0.2% (2/967) of ECGs contained significant artifacts. The novel cloud-computing algorithm for AF detection had a sensitivity of 95.5% (95% CI 77.2%-99.9%) and specificity of 97.7% (95% CI 96.5%-98.5%). The overall satisfaction score for the process of AF screening was 92.1%. AF screening in nonmetropolitan areas using a telehealth surveillance system with an embedded cloud-computing algorithm is feasible. ©Ying-Hsien Chen, Chi-Sheng Hung, Ching-Chang Huang, Yu-Chien Hung, Juey-Jen Hwang, Yi-Lwun Ho. Originally published in JMIR Mhealth and Uhealth (http://mhealth.jmir.org), 26.09.2017.

  14. Astrophysically relevant radiatively cooled hypersonic bow shocks in nested wire arrays

    NASA Astrophysics Data System (ADS)

    Ampleford, David

    2009-11-01

    We have performed laboratory experiments which introduce obstructions into hypersonic plasma flows to study the formation of shocks. Astrophysical observations have demonstrated many examples of equivalent radiatively cooled bow shocks, for example the head of protostellar jets or supernova remnants passing through the interstellar medium or between discrete clumps in jets. Wire array z-pinches allow us to study quasi-planar radiatively cooled flows in the laboratory. The early stage of a wire array z-pinch implosion consists of a steady flow of the wire material towards the axis. Given a high rate of radiative cooling, these flows reach high sonic- Mach numbers, typically up to 5. The 2D nature of this configuration allows the insertion of obstacles into the flow, such as a concentric ``inner'' wire array, as has previously been studied for ICF research. Here we study the application of such a nested array to laboratory astrophysics where the inner wires act as obstructions perpendicular to the flow, and induce bow shocks. By varying the wire array material (W/Al), the significance of radiative cooling on these shocks can be controlled, and is shown to change the shock opening angle. As multiple obstructions are present, the experiments show the interaction of multiple bow shocks. It is also possible to introduce a magnetic field around the static object, increasing the opening angle of the shocks. Further experiments can be designed to control the flow density, magnetic field structure and obstruction locations. In collaboration with: S.V. Lebedev, M.E. Cuneo, C.A. Jennings, S.N. Bland, J.P. Chittenden, A. Ciardi, G.N. Hall, S.C. Bott, M. Sherlock, A. Frank, E. Blackman

  15. Development of consistent hazard controls for DOE transuranic waste operations

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Woody, W.J.

    2007-07-01

    This paper describes the results of a re-engineering initiative undertaken with the Department of Energy's (DOE) Office of Environmental Management (EM) in order to standardize hazard analysis assumptions and methods and resulting safety controls applied to multiple transuranic (TRU) waste operations located across the United States. A wide range of safety controls are historically applied to transuranic waste operations, in spite of the fact that these operations have similar operational characteristics and hazard/accident potential. The re-engineering effort supported the development of a DOE technical standard with specific safety controls designated for accidents postulated during waste container retrieval, staging/storage, venting, onsitemore » movements, and characterization activities. Controls cover preventive and mitigative measures; include both hardware and specific administrative controls; and provide protection to the facility worker, onsite co-located workers and the general public located outside of facility boundaries. The Standard development involved participation from all major DOE sites conducting TRU waste operations. Both safety analysts and operations personnel contributed to the re-engineering effort. Acknowledgment is given in particular to the following individuals who formed a core working group: Brenda Hawks, (DOE Oak Ridge Office), Patrice McEahern (CWI-Idaho), Jofu Mishima (Consultant), Louis Restrepo (Omicron), Jay Mullis (DOE-ORO), Mike Hitchler (WSMS), John Menna (WSMS), Jackie East (WSMS), Terry Foppe (CTAC), Carla Mewhinney (WIPP-SNL), Stephie Jennings (WIPP-LANL), Michael Mikolanis (DOESRS), Kraig Wendt (BBWI-Idaho), Lee Roberts (Fluor Hanford), and Jim Blankenhorn (WSRC). Additional acknowledgment is given to Dae Chung (EM) and Ines Triay (EM) for leadership and management of the re-engineering effort. (authors)« less

  16. Update from the Analysis of High Resolution Propane Spectra and the Interpretation of Titan's Infrared Spectra

    NASA Technical Reports Server (NTRS)

    Klavans, V.; Nixon, C.; Hewagama, T.; Jennings, D. E.

    2012-01-01

    Titan has an extremely thick atmosphere dominated by nitrogen, but includes a range of trace species such as hydrocarbons and nitriles. One such hydrocarbon is propane (C3H8). Propane has 21 active IR bands covering broad regions of the mid-infrared. Therefore, its ubiquitous signature may potentially mask weaker signatures of other undetected species with important roles in Titan's chemistry. Cassini's Composite Infrared Spectrometer (CIRS) observations of Titan's atmosphere hint at the presence of such molecules. Unfortunately, C3H8 line atlases for the vibration bands V(sub 8), V(sub 21), V(sub 20), and V(sub 7) (869, 922, 1054, and 1157 per centimeter, respectively) are not currently available for subtracting the C3H8 signal to reveal, or constrain, the signature of underlying chemical species. Using spectra previously obtained by Jennings, D. E., et al. at the McMath-Pierce FTIR at Kitt Peak, AZ, as the source and automated analysis utilities developed for this application, we are compiling an atlas of spectroscopic parameters for propane that characterize the ro-vibrational transitions in the above bands. In this paper, we will discuss our efforts for inspecting and fitting the aforementioned bands, present updated results for spectroscopic parameters including absolute line intensities and transition frequencies in HITRAN and GEISA formats, and show how these optical constants will be used in searching for other trace chemical species in Titan's atmosphere. Our line atlas for the V(sub 21) band contains a total number of 2971 lines. The band integrated strength calculated for the V(sub 21) band is 1.003 per centimeter per (centimeter-atm).

  17. Screening of Genes Involved in Isooctane Tolerance in Saccharomyces cerevisiae by Using mRNA Differential Display

    PubMed Central

    Miura, Shigenori; Zou, Wen; Ueda, Mitsuyoshi; Tanaka, Atsuo

    2000-01-01

    A Saccharomyces cerevisiae strain, KK-211, isolated by the long-term bioprocess of stereoselective reduction in isooctane, showed extremely high tolerance to the solvent, which is toxic to yeast cells, but, in comparison with its wild-type parent, DY-1, showed low tolerance to hydrophilic organic solvents, such as dimethyl sulfoxide and ethanol. In order to detect the isooctane tolerance-associated genes, mRNA differential display (DD) was employed using mRNAs isolated from strains DY-1 and KK-211 cultivated without isooctane, and from strain KK-211 cultivated with isooctane. Thirty genes were identified as being differentially expressed in these three types of cells and were classified into three groups according to their expression patterns. These patterns were further confirmed and quantified by Northern blot analysis. On the DD fingerprints, the expression of 14 genes, including MUQ1, PRY2, HAC1, AGT1, GAC1, and ICT1 (YLR099c) was induced, while the expression of the remaining 16 genes, including JEN1, PRY1, PRY3, and KRE1, was decreased, in strain KK-211 cultivated with isooctane. The genes represented by HAC1, PRY1, and ICT1 have been reported to be associated with cell stress, and AGT1 and GAC1 have been reported to be involved in the uptake of trehalose and the production of glycogen, respectively. MUQ1 and KRE1, encoding proteins associated with cell surface maintenance, were also detected. Based on these results, we concluded that alteration of expression levels of multiple genes, not of a single gene, might be the critical determinant for isooctane tolerance in strain KK-211. PMID:11055939

  18. Vertical profile, contamination assessment, and source apportionment of heavy metals in sediment cores of Kaohsiung Harbor, Taiwan.

    PubMed

    Chen, Chih-Feng; Ju, Yun-Ru; Chen, Chiu-Wen; Dong, Cheng-Di

    2016-12-01

    Six sediment cores collected at the Kaohsiung Harbor of Taiwan were analyzed to evaluate their vertical profiles, enrichments, accumulations, and source apportionments of heavy metals. This was performed to investigate any potential ecological risks posed by heavy metals. Results indicated that the mean heavy metal content (mg kg -1 ) in the six sediment cores was as follows: Hg (0.4-6.4), Cd (<0.05-2.4), Cr (18-820), Cu (16-760), Pb (31-140), and Zn (76-1900). The patterns of heavy metal content in the sediment cores differed substantially among the four river mouths. However, the vertical profiles of metals were relatively stable, indicating that wastewater has the constant characteristics and has been discharged into the rivers for a long period of time. Results of pollution assessment of enrichment factor, geo-accumulation index, and pollution load index revealed that river mouths experience severe enrichment, strong accumulation, and high contamination from the primary heavy metals. It was not consistent in the assessment results of mean effect range median quotient, potential ecological risk index, and total toxic unit method. Potential ecological risks caused by Hg in the sediments at Canon River and Love River mouths on aquatic organisms were extremely high. The estimates derived from the receptor modeling of multiple linear regression of the absolute principal component scores indicated that the contributions of the composite heavy metals derived from the Canon River and the Love River on the potential toxicity and risks to the water environment of Kaohsiung Harbor were highest, followed by those derived from Salt River and Jen-Gen River. Copyright © 2016 Elsevier Ltd. All rights reserved.

  19. Sleep and Obesity: A focus on animal models

    PubMed Central

    Mavanji, Vijayakumar; Billington, Charles J.; Kotz, Catherine M.; Teske, Jennifer A.

    2012-01-01

    The rapid rise in obesity prevalence in the modern world parallels a significant reduction in restorative sleep (Agras et al., 2004; Dixon et al., 2007; Dixon et al., 2001; Gangwisch and Heymsfield, 2004; Gupta et al., 2002; Sekine et al., 2002; Vioque et al., 2000; Wolk et al., 2003). Reduced sleep time and quality increases the risk for obesity, but the underlying mechanisms remain unclear (Gangwisch et al., 2005; Hicks et al., 1986; Imaki et al., 2002; Jennings et al., 2007; Moreno et al., 2006). A majority of the theories linking human sleep disturbances and obesity rely on self-reported sleep. However, studies with objective measurements of sleep/wake parameters suggest a U-shaped relationship between sleep and obesity. Studies in animal models are needed to improve our understanding of the association between sleep disturbances and obesity. Genetic and experimenter-induced models mimicking characteristics of human obesity are now available and these animal models will be useful in understanding whether sleep disturbances determine propensity for obesity, or result from obesity. These models exhibit weight gain profiles consistently different from control animals. Thus a careful evaluation of animal models will provide insight into the relationship between sleep disturbances and obesity in humans. In this review we first briefly consider the fundamentals of sleep and key sleep disturbances, such as sleep fragmentation and excessive daytime sleepiness (EDS), observed in obese individuals. Then we consider sleep deprivation studies and the role of circadian alterations in obesity. We describe sleep/wake changes in various rodent models of obesity and obesity resistance. Finally, we discuss possible mechanisms linking sleep disturbances with obesity. PMID:22266350

  20. A systemic analysis of South Korea Sewol ferry accident - Striking a balance between learning and accountability.

    PubMed

    Kee, Dohyung; Jun, Gyuchan Thomas; Waterson, Patrick; Haslam, Roger

    2017-03-01

    The South Korea Sewol ferry accident in April 2014 claimed the lives of over 300 passengers and led to criminal charges of 399 personnel concerned including imprisonment of 154 of them as of Oct 2014. Blame and punishment culture can be prevalent in a more hierarchical society like South Korea as shown in the aftermath of this disaster. This study aims to analyse the South Korea ferry accident using Rasmussen's risk management framework and the associated AcciMap technique and to propose recommendations drawn from an AcciMap-based focus group with systems safety experts. The data for the accident analysis were collected mainly from an interim investigation report by the Board of Audit and Inspection of Korea and major South Korean and foreign newspapers. The analysis showed that the accident was attributed to many contributing factors arising from front-line operators, management, regulators and government. It also showed how the multiple factors including economic, social and political pressures and individual workload contributed to the accident and how they affected each other. This AcciMap was presented to 27 safety researchers and experts at 'the legacy of Jens Rasmussen' symposium adjunct to ODAM2014. Their recommendations were captured through a focus group. The four main recommendations include forgive (no blame and punishment on individuals), analyse (socio-technical system-based), learn (from why things do not go wrong) and change (bottom-up safety culture and safety system management). The findings offer important insights into how this type of accident should be understood, analysed and the subsequent response. Copyright © 2016 Elsevier Ltd. All rights reserved.

  1. Physician-assisted suicide and euthanasia: German Protestantism, conscience, and the limits of purely ethical reflection.

    PubMed

    Bartmann, Peter

    2003-01-01

    In this essay I shall describe and analyse the current debate on physician assisted suicide in contemporary German Protestant church and theology. It will be shown that the Protestant (mainly Lutheran) Church in Germany together with her Roman Catholic sister church has a specific and influential position in the public discussion: The two churches counting the majority of the population in Germany among their members tend to "organize" a social and political consensus on end-of-life questions. This cooperation is until now very successful: Speaking with one voice on end-of-life questions, the two churches function as the guardians of a moral consensus which is appreciated even by many non-believers. Behind this joint service to society the lines of the theological debate have to be ree-discovered. First it will be argued that a Protestant reading of the joint memoranda has to be based on the concept of individual conscience. The crucial questions are then: Whose conscience has the authority to decide? and: Can the physician assisted suicide be desired faithfully? Prominent in the current debate are Ulrich Eibach as a strict defender of the sanctity of life, and on the other side Walter Jens and Hans Kung, who argue for a right to physician assisted suicide under extreme conditions. I shall argue that it will be necessary to go beyond this actual controversy to the works of Gerhard Ebeling and Karl Barth for a clear and instructive account of conscience and a theological analysis of the concepts of life and suicide. On the basis of their considerations, a conscience-related approach to physician assisted suicide is developed.

  2. A novel flexible clinical multiphoton tomograph for early melanoma detection, skin analysis, testing of anti-age products, and in situ nanoparticle tracking

    NASA Astrophysics Data System (ADS)

    Weinigel, Martin; Breunig, Hans Georg; Gregory, Axel; Fischer, Peter; Kellner-Höfer, Marcel; Bückle, Rainer; König, Karsten

    2010-02-01

    High-resolution 3D microscopy based on multiphoton induced autofluorescence and second harmonic generation have been introduced in 1990. 13 years later, CE-marked clinical multiphoton systems for 3D imaging of human skin with subcellular resolution have first been launched by JenLab company with the tomography DermaInspect®. This year, the second generation of clinical multiphoton tomographs was introduced. The novel multiphoton tomograph MPTflex, equipped with a flexible articulated optical arm, provides an increased flexibility and accessibility especially for clinical and cosmetical examinations. Improved image quality and signal to noise ratio (SNR) are achieved by a very short source-drain spacing, by larger active areas of the detectors and by single photon counting (SPC) technology. Shorter image acquisition time due to improved image quality reduces artifacts and simplifies the operation of the system. The compact folded optical design and the light-weight structure of the optical head eases the handling. Dual channel detectors enable to distinguish between intratissue elastic fibers and collagenous structures simultaneously. Through the use of piezo-driven optics a stack of optical cross-sections (optical sectioning) can be acquired and 3D imaging can be performed. The multiphoton excitation of biomolecules like NAD(P)H, flavins, porphyrins, elastin, and melanin is done by picojoule femtosecond laser pulses from an tunable turn-key femtosescond near infrared laser system. The ability for rapid high-quality image acquisition, the user-friendly operation of the system and the compact and flexible design qualifies this system to be used for melanoma detection, diagnostics of dermatological disorders, cosmetic research and skin aging measurements as well as in situ drug monitoring and animal research.

  3. Geologic map of the East of Grotto Hills Quadrangle, California: a digital database

    USGS Publications Warehouse

    Nielson, Jane E.; Bedford, David R.

    1999-01-01

    The East of Grotto Hills 1:24,000-scale quadrangle of California lies west of the Colorado River about 30 km southwest of Searchlight, Nevada, near the boundary between the northern and southern parts of the Basin and Range Province. The quadrangle includes the eastern margin of Lanfair Valley, the southernmost part of the Castle Mountains, and part of the northwest Piute Range. The generally north-trending Piute Range aligns with the Piute and Dead Mountains of California and the Newberry and Eldorado Mountains and McCullough Range of Nevada. The southern part of the Piute Range adjoins Homer Mountain (Spencer and Turner, 1985) near Civil War-era Fort Piute. Adjacent 1:24,000-scale quadrangles include Castle Peaks, Homer Mountain, and Signal Hill, Calif.; also Hart Peak, Tenmile Well, and West of Juniper Mine, Calif. and Nev. The mapped area contains Tertiary (Miocene) volcanic and sedimentary rocks, interbedded with and overlain by Tertiary and Quaternary surficial deposits. Miocene intrusions mark conduits that served as feeders for the Miocene volcanic rocks, which also contain late magma pulses that cut the volcanic section. Upper Miocene conglomerate deposits interfinger with the uppermost volcanic flows. Canyons and intermontane valleys contain dissected Quaternary alluvial-fan deposits, mantled by active alluvial-fan deposits and detritus of active drainages. The alluvial materials were derived largely from Early Proterozoic granite and gneiss complexes, intruded by Mesozoic granite, dominate the heads of Lanfair Valley drainages in the New York Mountains and Mid Hills (fig. 1; Jennings, 1961). Similar rocks also underlie Tertiary deposits in the Castle Peaks, Castle Mountains, and eastern Piute Range.

  4. Alchemy, Chinese versus Greek, an etymological approach: a rejoinder.

    PubMed

    Mahdihassan, S

    1988-01-01

    The theory generally accepted maintains that Alchemy arose at Alexandria as a child of Greek culture. It has two names, Chemeia as the earlier and Chumeia as the later. There is another theory that Alchemy arose in China. Its founder was the aged ascetic who longed after drugs of longevity. He first tried jade, next gold and cinnabar, but the ideal was a drug which was red like cinnabar and fire-proof like gold. But what was actually prepared was red colloidal gold or "calcined gold," by grinding gold granules in a decoction of an herb of longevity. It was called Chin-I; Chin = gold and I = plant juice. In Fukin dialect Chin-I = Kim-Iya. This was Arabicized, by pre-Islamic Arabs trading in silk with China, as Kimiya, whence arose Al-Kimiya and finally Al-chemy. It was first accepted by Bucharic speaking Copts in Egypt who transliterated Kimiya = Chemeia, pronouncing it as the Arabs did. With the increase of trade in silk the Chinese also went to Alexandria and helped the Greeks to translate Chin-I as Chrusozomion meaning, gold (making) ferment, instead of gold making plant juice. Consistent with this origin of the word Chemeia is the fact that the earlier Alchemists were not Greeks but probably Bucharic speaks Copts or Egyptians. The consumer of Chin-I or Chemeia became "a drug-made immortal" called Chin-Jen, Golden-Man. This was translated into Greek as Chrusanthropos. Thus the etymoloogy of two Greek words Chrusozomion and Chrusanthropos support the origin of the loan word, Chemeia as Chinese. To save space it is not proposed to discuss the origin of Chumeia.

  5. Status and trends in suspended-sediment discharges, soil erosion, and conservation tillage in the Maumee River basin--Ohio, Michigan, and Indiana

    USGS Publications Warehouse

    Myers, Donna N.; Metzker, Kevin D.; Davis, Steven

    2000-01-01

    fields in the Maumee River Basin from 1993-98. Conservation tillage was used at relatively higher rates in areas draining to the lower main stem from Defiance to Waterville, Ohio and at relatively lower rates in the St. Marys and Auglaize River Basins, and in areas draining to the main stem between New Haven, Ind. and Defiance, Ohio. The areas that were identified as the most important sediment-source areas in the basin were characterized by some of the lowest rates of conservation tillage. The increased use of conservation tillage was found to correspond to decreases in suspended-sediment discharge over time at two locations in the Maumee River Basin. A 49.8 percent decrease in suspended-sediment discharge was detected when data from 1970-74 were compared to data from 1996-98 for the Auglaize River near Ft. Jennings, Ohio. A decrease in suspended-sediment discharge of 11.2 percent was detected from 1970?98 for the Maumee River at Waterville, Ohio. No trends in streamflow at either site were detected over the period 1970-98. The lower rate of decline in suspended-sediment discharge for the Maumee River at Waterville, Ohio compared to the Auglaize River near Ft. Jennings, may be due to resuspension and export of stored sediments from drainage ditches, stream channels, and flood plains in the large drainage basin upstream from Waterville. Similar findings by other investigators about the capacity of drainage networks to store sediment are supported by this investigation. These findings go undetected when soil loss estimates are used alone to evaluate the effectiveness of conservation tillage. Water-quality data in combination with soil-loss estimates were needed to draw these conclusions. These findings provide information to farmers and soil conservation agents about the ability of conservation tillage to reduce soil erosion and suspended-sediment discharge from the Maumee River Basin.

  6. The Effect of Agricultural Growing Season Change on Market Prices in Africa

    NASA Technical Reports Server (NTRS)

    deBeurs, K.M.; Brown, M. E.

    2013-01-01

    Local agricultural production is a key element of food security in many agricultural countries in Africa. Climate change and variability is likely to adversely affect these countries, particularly as they affect the ability of smallholder farmers to raise enough food to feed themselves. Seasonality influences farmers' decisions about when to sow and harvest, and ultimately the success or failure of their crops. At a 2009 conference in the United Kingdom hosted by the Institute of Development Studies, Jennings and Magrath (2009) described farmer reports from East Asia, South Asia, Southern Africa, East Africa and Latin America. Farmers indicate significant changes in the timing of rainy seasons and the pattern of rains within seasons, including: More erratic rainfall, coming at unexpected times in and out of season; Extreme storms and unusually intense rainfall are punctuated by longer dry spells within the rainy season; Increasing uncertainty as to the start of rainy seasons in many areas; Short or transitional second rainy seasons are becoming stronger than normal or are disappearing altogether. These farmer perceptions of change are striking in that they are geographically widespread and are remarkably consistent across diverse regions (Jennings and Magrath, 2009). The impact of these changes on farmers with small plots and few resources is large. Farming is becoming riskier because of heat stress, lack of water, pests and diseases that interact with ongoing pressures on natural resources. Lack of predictability in the start and length of the growing season affects the ability of farmers to invest in appropriate fertilizer levels or improved, high yielding varieties. These changes occur at the same time as the demand for food is rising and is projected to continue to rise for the next fifty years (IAASTD, 2008). Long-term data records derived from satellite remote sensing can be used to verify these reports, providing necessary analysis and documentation required

  7. "Culture" and the intergenerational transmission of poverty: the prevention paradox.

    PubMed

    Ludwig, Jens; Mayer, Susan

    2006-01-01

    Many U.S. policymakers support changing the "culture" of poor parents to encourage marriage, work, and religion as a means to end the intergenerational transmission of poverty. In this article Jens Ludwig and Susan Mayer review and evaluate research on how parental work, marriage, and religion affect children's socioeconomic status as adults, as well as on the likelihood that changing these indicators of parental behavior will reduce poverty in the next generation. They conclude that even if policymakers were able to ensure that all children had married, working, and religious parents, the result would be a far smaller reduction in poverty among the children's generation than many people believe. The explanation for this "poverty-prevention paradox," say Ludwig and Mayer, is that the poverty rate in the children's generation depends not only on how many poor children grow up to be poor adults, but also on how many nonpoor children grow up to be poor adults. Reducing the chances that poor children become poor adults will dramatically lower future poverty rates only if most poor adults begin life as poor children. But most poor adults grow up as nonpoor children in the type of "pro-social" households that policymakers are pushing to attain. Moreover, little good evidence supports the idea that such parental behaviors as marriage, work, and religious adherence have strong causal effects on children's long-term economic success. The authors argue that encouraging positive social behaviors in the parents of poor children is a worthwhile goal in its own right. But they stress that policymakers should recognize the limits of this strategy for reducing poverty among future generations. There may be no substitute for a system of social insurance and income transfers for those children who do wind up poor as adults.

  8. Sequence and Analysis of the Genome of the Pathogenic Yeast Candida orthopsilosis

    PubMed Central

    Riccombeni, Alessandro; Vidanes, Genevieve; Proux-Wéra, Estelle; Wolfe, Kenneth H.; Butler, Geraldine

    2012-01-01

    Candida orthopsilosis is closely related to the fungal pathogen Candida parapsilosis. However, whereas C. parapsilosis is a major cause of disease in immunosuppressed individuals and in premature neonates, C. orthopsilosis is more rarely associated with infection. We sequenced the C. orthopsilosis genome to facilitate the identification of genes associated with virulence. Here, we report the de novo assembly and annotation of the genome of a Type 2 isolate of C. orthopsilosis. The sequence was obtained by combining data from next generation sequencing (454 Life Sciences and Illumina) with paired-end Sanger reads from a fosmid library. The final assembly contains 12.6 Mb on 8 chromosomes. The genome was annotated using an automated pipeline based on comparative analysis of genomes of Candida species, together with manual identification of introns. We identified 5700 protein-coding genes in C. orthopsilosis, of which 5570 have an ortholog in C. parapsilosis. The time of divergence between C. orthopsilosis and C. parapsilosis is estimated to be twice as great as that between Candida albicans and Candida dubliniensis. There has been an expansion of the Hyr/Iff family of cell wall genes and the JEN family of monocarboxylic transporters in C. parapsilosis relative to C. orthopsilosis. We identified one gene from a Maltose/Galactoside O-acetyltransferase family that originated by horizontal gene transfer from a bacterium to the common ancestor of C. orthopsilosis and C. parapsilosis. We report that TFB3, a component of the general transcription factor TFIIH, undergoes alternative splicing by intron retention in multiple Candida species. We also show that an intein in the vacuolar ATPase gene VMA1 is present in C. orthopsilosis but not C. parapsilosis, and has a patchy distribution in Candida species. Our results suggest that the difference in virulence between C. parapsilosis and C. orthopsilosis may be associated with expansion of gene families. PMID:22563396

  9. Thermal Infrared Frontiers

    NASA Astrophysics Data System (ADS)

    Jennings, D. E.

    2002-05-01

    The solar spectrum between 5 and 28 microns has a rich diagnostic potential that is only now being realized. The ATST will have instrumentation specialized for this ``thermal" infrared region that will go well beyond present capabilities for solar magnetic field research. In particular, the MgI emission lines near 12 microns offer advantages for polarimetry. The Zeeman splittings in these lines are completely resolved at field strengths of a few hundred gauss. These lines are formed in the upper photosphere and, when used with data from the visible and near-infrared, produce three-dimensional pictures of the magnetic field. During the past two years, a team from Goddard Space Flight Center has been mapping vector fields in Stokes IQUV using a cryogenic grating spectrometer and a 12-micron polarization analyzer at the McMath-Pierce Telescope. On 24 April 2001 active region NOAA 9433 was mapped just before an M2 flare, revealing opposite polarity fields of 2700 and 1000 G within a single 2 arcsec pixel and implying a very high 5 G/km horizontal field gradient prior to the flare (1). In addition to polarimetry, there are advantages for imaging in the thermal infrared. The continuum brightness is a direct measure of temperature, and probes heights from 50 to 250 km at progressively longer wavelengths. The ATST will take advantage of the low light scattering and negligible instrumental polarization in the infrared, and will minimize thermal background. The large aperture of the ATST will produce unprecedented diffraction-limited spatial resolution at infrared wavelengths. This work is supported in part by NASA's Solar and Heliospheric Physics Program. (1) Jennings, D.E., Deming, D., McCabe, G., Sada, P.V., and Moran, T. 2002, ApJ, 568, April 1, to be published.

  10. Negatively-chirped laser enables nonlinear excitation and nanoprocessing with sub-20-fs pulses

    NASA Astrophysics Data System (ADS)

    Uchugonova, A.; Müller, J.; Bückle, R.; Tempea, G.; Isemann, A.; Stingl, A.; König, K.

    2008-02-01

    It has long been considered that the advantages emerging from employing chirp pre-compensation in nonlinear microscopy were overweighed by the complexity of prism- or grating-based compressors. These concerns were refuted with the advent of dispersive-mirrors-based compressors that are compact, user-friendly and sufficiently accurate to support sub-20-fs pulse delivery. Recent advances in the design of dispersive multilayer mirrors resulted in improved bandwidth (covering now as much as half of the gain bandwidth of Ti:Sapphire) and increased dispersion per bounce (one reflection off a state-of-the-art dispersive mirror pre-compensates the dispersion corresponding to >10mm of glass). The compressor built with these mirrors is sufficiently compact to be integrated in the housing of a sub-12-fs Ti:Sapphire oscillator. A complete scanning nonlinear microscope (FemtOgene, JenLab GmbH) equipped with highly-dispersive, large-NA objectives (Zeiss EC Plan-Neofluoar 40x/1.3, Plan-Neofluar 63x/1,25 Oil) was directly seeded with this negatively chirped laser. The pulse duration was measured at the focus of the objectives by inserting a scanning autocorrelator in the beam path between the laser and the microscope and recording the second order interferometric autocorrelation traces with the detector integrated in the microscope. Pulse durations <20fs were measured with both objectives. The system has been applied for two-photon imaging, transfection and optical manipulation of stem cells. Here we report on the successful transfection of human stem cells by transient optoporation of the cell membrane with a low mean power of < 7 mW and a short μs beam dwell time. Optically transfected cells were able to reproduce. The daughter cell expressed also green fluorescent proteins (GFP) indicating the successful modification of the cellular DNA.

  11. In-vivo multiphoton microscopy (MPM) of laser-induced optical breakdown (LIOB) in human skin (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Balu, Mihaela; Lentsch, Griffin; Korta, Dorota; Konig, Karsten; Kelly, Kristen M.; Tromberg, Bruce J.; Zachary, Christopher B.

    2017-02-01

    We use a multiphoton microscopy (MPM)-based clinical microscope (MPTflex, JenLab, Germany) to describe changes in human skin following treatment with a fractional non-ablative laser (PicoWay, Candela). The treatment was based on a fractionated picosecond Nd:YAG laser (1064 and 532nm, 3mJ and 1.5mJ (no attenuation), respectively maximum energy/pulse, 100 microbeams/6mmx6mm). Improvements in skin appearance resulting from treatment with this laser have been noted but optimizing the efficacy depends on a thorough understanding of the specific skin response to treatment. MPM is a nonlinear laser scanning microscopy technique that features sub-cellular resolution and label-free molecular contrast. MPM contrast in skin is derived from second-harmonic generation of collagen and two-photon excited fluorescence of NADH/FAD+, elastin, keratin, melanin. In this pilot study, two areas on the arm of a volunteer (skin type II) were treated with the picoWay laser (1064nm, 3mJ; 532nm, 1.5mJ; 1pass). The skin response to treatment was imaged in-vivo at 8 time points over the following 4 weeks. MPM revealed micro-injuries present in epidermis. Damaged individual cells were distinguished after 3h and 24h from treatment with both wavelengths. Pigmented cells were particularly damaged in the process, suggesting that melanin is the main absorber and the primary target for laser induced optical breakdown. At later time points, clusters of cellular necrotic debris were imaged across the treated epidermis. These results represent the groundwork for future longitudinal studies on expanded number of subjects to understand the response to treatment in different skin types at different laser parameters, critical factors in optimizing treatment outcomes.

  12. A new reference global instrumental earthquake catalogue (1900-2009)

    NASA Astrophysics Data System (ADS)

    Di Giacomo, D.; Engdahl, B.; Bondar, I.; Storchak, D. A.; Villasenor, A.; Bormann, P.; Lee, W.; Dando, B.; Harris, J.

    2011-12-01

    For seismic hazard studies on a global and/or regional scale, accurate knowledge of the spatial distribution of seismicity, the magnitude-frequency relation and the maximum magnitudes is of fundamental importance. However, such information is normally not homogeneous (or not available) for the various seismically active regions of the Earth. To achieve the GEM objectives (www.globalquakemodel.org) of calculating and communicating earthquake risk worldwide, an improved reference global instrumental catalogue for large earthquakes spanning the entire 100+ years period of instrumental seismology is an absolute necessity. To accomplish this task, we apply the most up-to-date techniques and standard observatory practices for computing the earthquake location and magnitude. In particular, the re-location procedure benefits both from the depth determination according to Engdahl and Villaseñor (2002), and the advanced technique recently implemented at the ISC (Bondár and Storchak, 2011) to account for correlated error structure. With regard to magnitude, starting from the re-located hypocenters, the classical surface and body-wave magnitudes are determined following the new IASPEI standards and by using amplitude-period data of phases collected from historical station bulletins (up to 1970), which were not available in digital format before the beginning of this work. Finally, the catalogue will provide moment magnitude values (including uncertainty) for each seismic event via seismic moment, via surface wave magnitude or via other magnitude types using empirical relationships. References Engdahl, E.R., and A. Villaseñor (2002). Global seismicity: 1900-1999. In: International Handbook of Earthquake and Engineering Seismology, eds. W.H.K. Lee, H. Kanamori, J.C. Jennings, and C. Kisslinger, Part A, 665-690, Academic Press, San Diego. Bondár, I., and D. Storchak (2011). Improved location procedures at the International Seismological Centre, Geophys. J. Int., doi:10.1111/j

  13. The Atmospheres of Titan and Saturn in the Infrared from Cassini: The Interplay Between Observation and Laboratory Studies

    NASA Technical Reports Server (NTRS)

    Jennings, D. E.; Nixon, C. A.; Flasar, F. M.; Kunde, V. G.; Coustenis, A.

    2011-01-01

    The Composite Infrared Spectrometer (CIRS) aboard the Cassini spacecraft has been recording spectra of Saturn and Titan since its arrival in the Saturn system in 2004. CIRS, a Fourier transform spectrometer, observes the thermal infrared spectrum of both atmospheres from 10 to 1500/cm with resolutions up to 0.5/cm (Flasar et al. 2004). From these data CIRS provides global coverage of the molecular composition of the stratosphere and troposphere, as well as maps of temperature and winds. From such studies CIRS helps reveal the chemistry and evolutionary history of Saturn and Titan and their relationships to other Solar System bodies. The Cassini mission is continuing until 2017, permitting CIRS to search for atmospheric changes during more than a Saturnian season. By combining with results from Voyager (1980, 1981) the baseline becomes more than one Saturnian year (Coustenis et al. 2011). CIRS spectroscopy of the atmospheres of Saturn and Titan has raised a variety of questions that require new laboratory studies. A complete understanding of the CIRS high-resolution atmospheric spectra cannot be fully achieved without new or improved line positions and intensities for some trace molecules (e.g., Nixon et al. 2009). Isotopic variants of some of the more abundant species often need improved line parameters in order to derive isotopic ratios (e.g., Coustenis et al. 2008 and Fletcher et a!. 2009). Isotopic ratios contain information about the history of an atmosphere if experimental fractionation rates are available (Jennings et al. 2009). Some aerosol and haze features continue to defy identification and will not be explained without better knowledge of how these materials are formed and until we obtain their laboratory spectra. The interaction between CIRS investigations and laboratory research has been productive and has already led to new discoveries.

  14. Involvement of aquaporin NIP1;1 in the contrasting tolerance response to root hypoxia in Prunus rootstocks.

    PubMed

    Mateluna, Patricio; Salvatierra, Ariel; Solis, Simón; Nuñez, Gabriel; Pimentel, Paula

    2018-05-12

    Prunus species have been classified as moderately sensitive to root hypoxia, but with a certain intrageneric tolerance degree to oxygen deficiency. Previously, RNA-seq analysis described the transcriptomic reconfiguration of two Prunus rootstocks contrasting to root hypoxia, which included the shift from aerobic to anaerobic metabolism. Here, we studied the relationship between lactate accumulation and the functionality of an aquaporin differentially expressed in 'Mariana 2624', a plum-based (Prunus cerasifera x Prunus munsoniana) rootstock tolerant to root hypoxia stress, and 'Mazzard F12/1', a cherry-based (Prunus avium) rootstock sensitive to root hypoxia stress. In the root hypoxia-sensitive rootstock, higher levels of lactate and LDH1 gene expression were found in roots exposed to oxygen deprivation. Concomitantly, we detected an increase in the mRNA abundance of Prunus spp. NIP1;1, a putative lactic acid transporter. Intriguingly, the high expression of PruavNIP1;1 is not linked to a lower lactic acid content in the roots of 'Mazzard F12/1'. To study this phenomenon, we calculated the force required for the transit of a lactic acid molecule through Prunus spp. NIP1;1 channels. Comparing the calculated forces, we identified steric hindrances in PruavNIP1;1 given by the residues Phe107 and Trp88 in the NPA region and ar/R filter, respectively. The functionality of both channels was corroborated by the restoration of the lactic acid transport and the differential lactic acid sensitive-phenotypes of the yeast strain Δjen1 complemented with PruavNIP1;1 and PrucxmNIP1;1. Our findings provide new insights into the mechanisms involved in determining hypoxia tolerance between closely related species, such as plum and cherry. Copyright © 2018 Elsevier GmbH. All rights reserved.

  15. Google Earth Grand Tour Themes

    NASA Astrophysics Data System (ADS)

    De Paor, D. G.; Whitmeyer, S. J.; Bentley, C.; Dordevic, M. M.

    2014-12-01

    As part of an NSF TUES Type 3 project entitled "Google Earth for Onsite and Distance Education (GEODE)," we are assembling a "Grand Tour" of locations on Earth and other terrestrial bodies that every geoscience student should know about and visit at least in virtual reality. Based on feedback from colleagues at previous meetings, we have identified nine Grand Tour themes: "Plates and Plumes," "Rocks and Regions," "Geology Through Time," "The Mapping Challenge*," "U.S. National Parks*," "The Magical Mystery Tour*," "Resources and Hazards," "Planets and Moons," and "Top of the Pops." Themes marked with an asterisk are most developed at this stage and will be demonstrated in real time. The Mapping Challenge invites students to trace geological contacts, measure bedding strike and dip and the plunge, trend, and facing of a fold. There is an advanced tool for modeling periclinal folds. The challenge is presented in a game-like format with an emphasis on puzzle-solving that will appeal to students regardless of gender. For the tour of U.S. national parks, we divided the most geologically important parks into four groups—Western Pacific, West Coast, Rockies, and East Coast. We are combining our own team's GigaPan imagery with imagery already available on the Internet. There is a great deal of imagery just waiting to be annotated for geological education purposes. The Magical Mystery Tour takes students to Google Streetview locations selected by instructors. Students are presented with questions or tasks and are given automatic feedback. Other themes are under development. Within each theme, we are crowd-sourcing contributions from colleagues and inviting colleagues to vote for or against proposed locations and student interactions. The GEODE team includes the authors and: Heather Almquist, Stephen Burgin, Cinzia Cervato, Gene Cooper, Paul Karabinos, Terry Pavlis, Jen Piatek, Bill Richards, Jeff Ryan, Ron Schott, Kristen St. John, and Barb Tewksbury.

  16. Fifty Years of THERP and Human Reliability Analysis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ronald L. Boring

    2012-06-01

    In 1962 at a Human Factors Society symposium, Alan Swain presented a paper introducing a Technique for Human Error Rate Prediction (THERP). This was followed in 1963 by a Sandia Laboratories monograph outlining basic human error quantification using THERP and, in 1964, by a special journal edition of Human Factors on quantification of human performance. Throughout the 1960s, Swain and his colleagues focused on collecting human performance data for the Sandia Human Error Rate Bank (SHERB), primarily in connection with supporting the reliability of nuclear weapons assembly in the US. In 1969, Swain met with Jens Rasmussen of Risø Nationalmore » Laboratory and discussed the applicability of THERP to nuclear power applications. By 1975, in WASH-1400, Swain had articulated the use of THERP for nuclear power applications, and the approach was finalized in the watershed publication of the NUREG/CR-1278 in 1983. THERP is now 50 years old, and remains the most well known and most widely used HRA method. In this paper, the author discusses the history of THERP, based on published reports and personal communication and interviews with Swain. The author also outlines the significance of THERP. The foundations of human reliability analysis are found in THERP: human failure events, task analysis, performance shaping factors, human error probabilities, dependence, event trees, recovery, and pre- and post-initiating events were all introduced in THERP. While THERP is not without its detractors, and it is showing signs of its age in the face of newer technological applications, the longevity of THERP is a testament of its tremendous significance. THERP started the field of human reliability analysis. This paper concludes with a discussion of THERP in the context of newer methods, which can be seen as extensions of or departures from Swain’s pioneering work.« less

  17. Investigation of trailing mass in Z-pinch implosions and comparison to experiment

    NASA Astrophysics Data System (ADS)

    Yu, Edmund

    2007-11-01

    Wire-array Z pinches represent efficient, high-power x-ray sources with application to inertial confinement fusion, high energy density plasmas, and laboratory astrophysics. The first stage of a wire-array Z pinch is described by a mass ablation phase, during which stationary wires cook off material, which is then accelerated radially inwards by the JxB force. The mass injection rate varies axially and azimuthally, so that once the ablation phase concludes, the subsequent implosion is highly 3D in nature. In particular, a network of trailing mass and current is left behind the imploding plasma sheath, which can significantly affect pinch performance. In this work we focus on the implosion phase, electing to model the mass ablation via a mass injection scheme. Such a scheme has a number of injection parameters, but this freedom also allows us to gain understanding into the nature of the trailing mass network. For instance, a new result illustrates the role of azimuthal correlation. For an implosion which is 100% azimuthally correlated (corresponding to an azimuthally symmetric 2D r-z problem), current is forced to flow on the imploding plasma sheath, resulting in strong Rayleigh-Taylor (RT) growth. If, however, the implosion is not azimuthally symmetric, the additional azimuthal degree of freedom opens up new conducting paths of lower magnetic energy through the trailing mass network, effectively reducing RT growth. Consequently the 3D implosion experiences lower RT growth than the 2D r-z equivalent, and actually results in a more shell-like implosion. A second major goal of this work is to constrain the injection parameters by comparison to a well-diagnosed experimental data set, in which array mass was varied. In collaboration with R. Lemke, M. Desjarlais, M. Cuneo, C. Jennings, D. Sinars, E. Waisman

  18. Field trial of a pulsed limestone diversion well

    USGS Publications Warehouse

    Sibrell, Philip L.; Denholm, C.; Dunn, Margaret

    2013-01-01

    The use of limestone diversion wells to treat acid mine drainage (AMD) is well-known, but in many cases, acid neutralization is not as complete as would be desired. Reasons for this include channeling of the water through the limestone bed, and the slow reaction rate of the limestone gravel. A new approach to improve the performance of the diversion well was tested in the field at the Jennings Environmental Education Center, near Slippery Rock, PA. In this approach, a finer size distribution of limestone was used so as to allow fluidization of the limestone bed, thus eliminating channeling and increasing particle surface area for faster reaction rates. Also, water flow was regulated through the use of a dosing siphon, so that consistent fluidization of the limestone sand could be achieved. Testing began late in the summer of 2010, and continued through November of 2011. Initial system performance during the 2010 field season was good, with the production of net alkaline water, but hydraulic problems involving air release and limestone sand retention were observed. In the summer of 2011, a finer size of limestone sand was procured for use in the system. This material fluidized more readily, but acid neutralization tapered off after several days. Subsequent observations indicated that the hydraulics of the system was compromised by the formation of iron oxides in the pipe leading to the limestone bed, which affected water distribution and flow through the bed. Although results from the field trial were mixed, it is believed that without the formation of iron oxides and plugging of the pipe, better acid neutralization and treatment would have occurred. Further tests are being considered using a different hydraulic configuration for the limestone sand fluidized bed.

  19. Results of continuous monitoring of the performance of rubella virus IgG and hepatitis B virus surface antibody assays using trueness controls in a multicenter trial.

    PubMed

    Kruk, Tamara; Ratnam, Sam; Preiksaitis, Jutta; Lau, Allan; Hatchette, Todd; Horsman, Greg; Van Caeseele, Paul; Timmons, Brian; Tipples, Graham

    2012-10-01

    We conducted a multicenter trial in Canada to assess the value of using trueness controls (TC) for rubella virus IgG and hepatitis B virus surface antibody (anti-HBs) serology to determine test performance across laboratories over time. TC were obtained from a single source with known international units. Seven laboratories using different test systems and kit lots included the TC in routine assay runs of the analytes. TC measurements of 1,095 rubella virus IgG and 1,195 anti-HBs runs were plotted on Levey-Jennings control charts for individual laboratories and analyzed using a multirule quality control (MQC) scheme as well as a single three-standard-deviation (3-SD) rule. All rubella virus IgG TC results were "in control" in only one of the seven laboratories. Among the rest, "out-of-control" results ranged from 5.6% to 10% with an outlier at 20.3% by MQC and from 1.1% to 5.6% with an outlier at 13.4% by the 3-SD rule. All anti-HBs TC results were "in control" in only two laboratories. Among the rest, "out-of-control" results ranged from 3.3% to 7.9% with an outlier at 19.8% by MQC and from 0% to 3.3% with an outlier at 10.5% by the 3-SD rule. In conclusion, through the continuous monitoring of assay performance using TC and quality control rules, our trial detected significant intra- and interlaboratory, test system, and kit lot variations for both analytes. In most cases the assay rejections could be attributable to the laboratories rather than to kit lots. This has implications for routine diagnostic screening and clinical practice guidelines and underscores the value of using an approach as described above for continuous quality improvement in result reporting and harmonization for these analytes.

  20. A single mutation near the C-terminus in alpha/beta hydrolase fold protein family causes a defect in protein processing.

    PubMed

    De Jaco, Antonella; Kovarik, Zrinka; Comoletti, Davide; Jennings, Lori L; Gaietta, Guido; Ellisman, Mark H; Taylor, Palmer

    2005-12-15

    An Arg to Cys mutation in the extracellular domain of neuroligin-3 (NL3) was recently found in a twin set with autism [S. Jamain, H. Quach, C. Betancur, M. Rastam, C. Colineaux, I.C. Gillberg, H. Soderstrom, B. Giros, M. Leboyer, C. Gillberg, T. Bourgeron, Paris Autism Research International Sibpair Study, mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism, Nat. Genet. 34 (2003) 27-29]. The Cys substitution in NL3 causes altered intracellular protein trafficking, intracellular retention and diminished association with its cognate partner, beta-neurexin [D. Comoletti, A. De Jaco, L.L. Jennings, R.E. Flynn, G. Gaietta, I. Tsigelny, M.H. Ellisman, P. Taylor, The R451C-neuroligin-3 mutation associated with autism reveals a defect in protein processing, J. Neurosci. 24 (2004) 4889-4893]. NL3, butyrylcholinesterase (BuChE), and acetylcholinesterase (AChE), as members of the (/(-hydrolase fold family of proteins, share over 30% of amino acid identity in their extracellular domains. In particular, Arg451 in NL3 is conserved in the alpha/beta-hydrolase fold family being homologous to Arg386 in BuChE and Arg395 in AChE. A Cys substitution at the homologous Arg in the BuChE was found studying post-succinylcholine apnea in an Australian population [T. Yen, B.N. Nightingale, J.C. Burns, D.R. Sullivan, P.M. Stewart, Butyrylcholinesterase (BCHE) genotyping for post-succinylcholine apnea in an Australian population, Clin. Chem. 49 (2003) 1297-308]. We have made the homologous mutation in the mouse AChE and BuChE genes and showed that the Arg to Cys mutations resulted in identical alterations in the cellular phenotype for the various members of the alpha/beta-hydrolase fold family proteins.

  1. Enhancing the Meaningfulness of Work for Astronauts on Long Duration Space Exploration Missions.

    PubMed

    Britt, Thomas W; Sytine, Anton; Brady, Ashley; Wilkes, Russ; Pittman, Rebecca; Jennings, Kristen; Goguen, Kandice

    2017-08-01

    Numerous authors have identified the stressors likely to be encountered on long duration space exploration missions (e.g., to Mars), including the possibility of significant crises, separation from family, boredom/monotony, and interpersonal conflict. Although many authors have noted that meaningful work may be beneficial for astronauts on these missions, none have detailed the sources of meaningful work for astronauts and how these sources may differ between astronauts. The present article identifies how engagement in meaningful work during long duration missions may mitigate the adverse effects of demands and increase the potential for benefits resulting from the missions. Semistructured interviews were conducted with nine NASA personnel, including astronauts, flight directors, and flight surgeons. Questions addressed sources of meaning for astronauts, characteristics of tasks that enhance vs. detract from meaning, and recommendations for enhancing meaning. Personnel mentioned contributing to humanity and the next generation, contributing to the mission, and exploration as the most meaningful aspects of their work. Characteristics of tasks that enhanced meaning included using a variety of skills, feeling personal control over their schedule, autonomy in the execution of tasks, and understanding the importance of the experiments conducted on the mission. Top recommendations to sustain meaning were insuring social needs were met through such activities as the strategic use of social media, giving astronauts autonomy as well as structure, and conducting training during transit. Implications are addressed for tailoring meaning-based interventions for astronauts participating on long duration missions and assessing the effectiveness of these interventions.Britt TW, Sytine A, Brady A, Wilkes R, Pittman R, Jennings K, Goguen K. Enhancing the meaningfulness of work for astronauts on long duration space exploration missions. Aerosp Med Hum Perform. 2017; 88(8):779-783.

  2. Large ground surface temperature changes of the last three centuries inferred from borehole temperatures in the Southern Canadian Prairies, Saskatchewan

    NASA Astrophysics Data System (ADS)

    Majorowicz, Jacek A.; Safanda, Jan; Harris, Robert N.; Skinner, Walter R.

    1999-05-01

    New temperature logs in wells located in the grassland ecozone in the Southern Canadian Prairies in Saskatchewan, where surface disturbance is considered minor, show a large curvature in the upper 100 m. The character of this curvature is consistent with ground surface temperature (GST) warming in the 20th century. Repetition of precise temperature logs in southern Saskatchewan (years 1986 and 1997) shows the conductive nature of warming of the subsurface sediments. The magnitude of surface temperature change during that time (11 years) is high (0.3-0.4°C). To assess the conductive nature of temperature variations at the grassland surface interface, several precise air and soil temperature time series in the southern Canadian Prairies (1965-1995) were analyzed. The combined anomalies correlated at 0.85. Application of the functional space inversion (FSI) technique with the borehole temperature logs and site-specific lithology indicates a warming to date of approximately 2.5°C since a minimum in the late 18th century to mid 19th century. This warming represents an approximate increase from 4°C around 1850 to 6.5°C today. The significance of this record is that it suggests almost half of the warming occurred prior to 1900, before dramatic build up of atmospheric green house gases. This result correlates well with the proxy record of climatic change further to the north, beyond the Arctic Circle [Overpeck, J., Hughen, K., Hardy, D., Bradley, R., Case, R., Douglas, M., Finney, B., Gajewski, K., Jacoby, G., Jennings, A., Lamourex, S., Lasca, A., MacDonald, G., Moore, J., Retelle, M., Smith, S., Wolfe, A., Zielinski, G., 1997. Arctic environmental change of the last four centuries, Science 278, 1251-1256.].

  3. Leveraging Google Geo Tools for Interactive STEM Education: Insights from the GEODE Project

    NASA Astrophysics Data System (ADS)

    Dordevic, M.; Whitmeyer, S. J.; De Paor, D. G.; Karabinos, P.; Burgin, S.; Coba, F.; Bentley, C.; St John, K. K.

    2016-12-01

    Web-based imagery and geospatial tools have transformed our ability to immerse students in global virtual environments. Google's suite of geospatial tools, such as Google Earth (± Engine), Google Maps, and Street View, allow developers and instructors to create interactive and immersive environments, where students can investigate and resolve common misconceptions in STEM concepts and natural processes. The GEODE (.net) project is developing digital resources to enhance STEM education. These include virtual field experiences (VFEs), such as an interactive visualization of the breakup of the Pangaea supercontinent, a "Grand Tour of the Terrestrial Planets," and GigaPan-based VFEs of sites like the Canadian Rockies. Web-based challenges, such as EarthQuiz (.net) and the "Fold Analysis Challenge," incorporate scaffolded investigations of geoscience concepts. EarthQuiz features web-hosted imagery, such as Street View, Photo Spheres, GigaPans, and Satellite View, as the basis for guided inquiry. In the Fold Analysis Challenge, upper-level undergraduates use Google Earth to evaluate a doubly-plunging fold at Sheep Mountain, WY. GEODE.net also features: "Reasons for the Seasons"—a Google Earth-based visualization that addresses misconceptions that abound amongst students, teachers, and the public, many of whom believe that seasonality is caused by large variations in Earth's distance from the Sun; "Plate Euler Pole Finder," which helps students understand rotational motion of tectonic plates on the globe; and "Exploring Marine Sediments Using Google Earth," an exercise that uses empirical data to explore the surficial distribution of marine sediments in the modern ocean. The GEODE research team includes the authors and: Heather Almquist, Cinzia Cervato, Gene Cooper, Helen Crompton, Terry Pavlis, Jen Piatek, Bill Richards, Jeff Ryan, Ron Schott, Barb Tewksbury, and their students and collaborating colleagues. We are supported by NSF DUE 1323419 and a Google Geo

  4. Applying the AcciMap methodology to investigate the tragic Sewol Ferry accident in South Korea.

    PubMed

    Lee, Samuel; Moh, Young Bo; Tabibzadeh, Maryam; Meshkati, Najmedin

    2017-03-01

    This study applies the AcciMap methodology, which was originally proposed by Professor Jens Rasmussen (1997), to the analysis of the tragic Sewol Ferry accident in South Korea on April 16, 2014, which killed 304 mostly young people and is considered as a national disaster in that country. This graphical representation, by incorporating associated socio-technical factors into an integrated framework, provides a big-picture to illustrate the context in which an accident occurred as well as the interactions between different levels of the studied system that resulted in that event. In general, analysis of past accidents within the stated framework can define the patterns of hazards within an industrial sector. Such analysis can lead to the definition of preconditions for safe operations, which is a main focus of proactive risk management systems. In the case of the Sewol Ferry accident, a lot of the blame has been placed on the Sewol's captain and its crewmembers. However, according to this study, which relied on analyzing all available sources published in English and Korean, the disaster is the result of a series of lapses and disregards for safety across different levels of government and regulatory bodies, Chonghaejin Company, and the Sewol's crewmembers. The primary layers of the AcciMap framework, which include the political environment and non-proactive governmental body; inadequate regulations and their lax oversight and enforcement; poor safety culture; inconsideration of human factors issues; and lack of and/or outdated standard operating and emergency procedures were not only limited to the maritime industry in South Korea, and the Sewol Ferry accident, but they could also subject any safety-sensitive industry anywhere in the world. Copyright © 2016 Elsevier Ltd. All rights reserved.

  5. National Program of Inspection of Non-Federal Dams, Tennessee. Jennings Creek Watershed Dam Number 15 (Inventory Number TN 08705), Cumberland River Basin, near North Springs, Jackson County, Tennessee. Phase I Investigation Report,

    DTIC Science & Technology

    1981-06-01

    acres (0.766 mi2 ). Major soil types in the watershed include Bodine, Mountview, Delrose, Dickson, and Mimosa . The drainage area is mountainous and...Bodine, Mountview, Delrose, Dickson, Mimosa c. Average slope - 40% d. Land use - Woods, pasture, few roads, and isolated structures e. Runoff from...490 acres (0.766 mi2) B. Average Channel Slope 2% C. Average Land Slope 40% D. Hydrologic Soil Group 90% C (Dickson, Mimosa ) E. Time of Concentration

  6. Reply to "Comment on 'Cosmic-ray-driven reaction and greenhouse effect of halogenated molecules: Culprits for atmospheric ozone depletion and global climate change' by Rolf Müller and Jens-Uwe Grooß"

    NASA Astrophysics Data System (ADS)

    Lu, Q.-B.

    2014-04-01

    In their Comment, Müller and Grooß continuously use problematic "observed data" and misleading arguments to make a case against our CRE mechanism of the ozone hole and CFC-warming mechanism of global climate change. They make the groundless assertion that the CRE theory cannot be considered as an independent process for ozone loss in the polar stratosphere. Their claim that the impact of the CRE mechanism on polar chlorine activation and ozone loss in the stratosphere would be limited does not agree with the observed data over the past decades. They also make many contradictory and fact-distorting arguments that "There is no polar ozone loss in darkness, there is no apparent 11-year periodicity in polar total ozone measurements, the age of air in the polar lower stratosphere is much older than 1-2 years, and the reported detection of a pronounced recovery (by about 20-25%) in Antarctic total ozone measurements by the year 2010 is in error." These assertions ignore and contradict a great deal of robust observed data from both laboratory and field measurements reported in the literature including their own publications. Their new argument for the photodissociation of CFCs on PSCs also contradicts their previous extraordinary efforts including the use of fabricated "ACE-FTS satellite data" to argue for no physical/chemical loss of CFCs in the winter lower polar stratosphere. Finally, they do not provide any scientific evidence to support their criticism for the no physical basis of the CFC-warming theory and its conclusions. In summary, their misleading arguments and false "data" do not change the convincing conclusion reached by robust observations in my recent paper that both the CRE mechanism and the CFC-warming mechanism not only provide new fundamental understandings of the O3 hole and global climate change but have superior predictive capabilities, compared with the conventional models.

  7. New Line Lists for planetological applications: HC3N and C4H2

    NASA Astrophysics Data System (ADS)

    Jolly, A.; Benilan, Y.; Fayt, A.

    2009-04-01

    The Composite Infrared Spectrometer (CIRS) on-board Cassini, after four years of operation in Saturnian orbit with over thirty close fly-bys of Titan, has obtained spectra in the far and mid-infrared with a spectral resolution of 0.5 cm-1. Mismatch between observed spectra and model spectra obtained from the available line lists has led us to study the bending bands of HC3N and C4H2, the longest carbon chains observed on Titan. Our experimental study for HC3N (Jolly et al. 2007, J.Mol.Spec) has shown that band intensities had to be revised and that including hot bands with lower level as high as 1300 cm-1 was necessary to model our experimental spectra at 0.5 cm-1 resolution. A new extended line list could be obtained by fitting high resolution data with the help of a global analysis. This line list was made available to the astronomers of the CIRS team and will be included in the next version of the GEISA data base. Thanks to the precision of the new spectroscopic data, 13C isotopologues of HC3N have been detected and quantified for the first time in the atmosphere of Titan (Jennings et al. 2008, ApJL). Search for the 15N isotopologues of HC3N will also be presented. The proportion of hot bands is even more important for C4H2 than for HC3N and a new extended line list was absolutely necessary to improve the CIRS spectral analysis. We will present a new line list and show comparison between synthetic spectra and experimental spectra of C4H2 obtained between 193 and 296 K at 0.1 and 0.5 cm-1 resolution. Comparison of model spectra to CIRS observations of C4H2 at 220 and 630 cm-1 will also be presented. Detections of hot bands and isotopes in cold environments such as Titan will be emphasized.

  8. PREFACE: Beyond Kyoto - the necessary road

    NASA Astrophysics Data System (ADS)

    Margrethe Basse, Ellen

    2009-03-01

    The Beyond Kyoto conference in Aarhus March 2009 was organised in collaboration with other knowledge institutions, businesses and authorities. It brought together leading scientists, policy-makers, authorities, intergovernmental organisations, NGO's, business stakeholders and business organisations. The conference was a joint interdisciplinary project involving many academic areas and disciplines. These conference proceedings are organised in central and recurring themes that cut across many debates on climate change, the climatic challenges as well as the solutions. In the front there is a short presentation of the conference concept. Part I of the proceedings focuses on issues related to the society - covering climate policy, law, market based instruments, financial structure, behaviour and consumption, public participation, media communication and response from indigenous peoples etc. Part II of the proceedings concerns the scientific knowledge base on climate related issues - covering climate change processes per se, the potential impacts of projected climate change on biodiversity and adaptation possibilities, the interplay between climate, agriculture and biodiversity, emissions, agricultural systems, increasing pressure on the functioning of agriculture and natural areas, vulnerability to extreme weather events and risks in respect to sea-level rise etc. The conference proceedings committee consists of four professors from Aarhus University: Jens-Christian Svenning, Jørgen E Olesen, Mads Forchhammer and Ellen Margrethe Basse. Aarhus University's Climate Secretariat has had the overall responsibility for coordinating the many presentations, as well as the practical side of arranging the conference and supporting the publication of papers. As Head of the Climate Secretariat and Chair of Aarhus University's Climate Panel, I would like to thank everyone for their contribution. This applies both to the scientific and the practical efforts. Special thanks to

  9. Illness, medical expenditure and household consumption: observations from Taiwan

    PubMed Central

    2013-01-01

    Background Illness conditions lead to medical expenditure. Even with various types of medical insurance, there can still be considerable out-of-pocket costs. Medical expenditure can affect other categories of household consumptions. The goal of this study is to provide an updated empirical description of the distributions of illness conditions and medical expenditure and their associations with other categories of household consumptions. Methods A phone-call survey was conducted in June and July of 2012. The study was approved by ethics review committees at Xiamen University and FuJen Catholic University. Data was collected using a Computer-Assisted Telephone Survey System (CATSS). “Household” was the unit for data collection and analysis. Univariate and multivariate analyses were conducted, examining the distributions of illness conditions and the associations of illness and medical expenditure with other household consumptions. Results The presence of chronic disease and inpatient treatment was not significantly associated with household characteristics. The level of per capita medical expenditure was significantly associated with household size, income, and household head occupation. The presence of chronic disease was significantly associated with levels of education, insurance and durable goods consumption. After adjusting for confounders, the associations with education and durable goods consumption remained significant. The presence of inpatient treatment was not associated with consumption levels. In the univariate analysis, medical expenditure was significantly associated with all other consumption categories. After adjusting for confounding effects, the associations between medical expenditure and the actual amount of entertainment expenses and percentages of basic consumption, savings, and insurance (as of total consumption) remained significant. Conclusion This study provided an updated description of the distributions of illness conditions and

  10. A hydraulic-photosynthetic model based on extended HLH and its application to Coast redwood (Sequoia sempervirens).

    PubMed

    Du, Ning; Fan, Jintu; Chen, Shuo; Liu, Yang

    2008-07-21

    Although recent investigations [Ryan, M.G., Yoder, B.J., 1997. Hydraulic limits to tree height and tree growth. Bioscience 47, 235-242; Koch, G.W., Sillett, S.C.,Jennings, G.M.,Davis, S.D., 2004. The limits to tree height. Nature 428, 851-854; Niklas, K.J., Spatz, H., 2004. Growth and hydraulic (not mechanical) constraints govern the scaling of tree height and mass. Proc. Natl Acad. Sci. 101, 15661-15663; Ryan, M.G., Phillips, N., Bond, B.J., 2006. Hydraulic limitation hypothesis revisited. Plant Cell Environ. 29, 367-381; Niklas, K.J., 2007. Maximum plant height and the biophysical factors that limit it. Tree Physiol. 27, 433-440; Burgess, S.S.O., Dawson, T.E., 2007. Predicting the limits to tree height using statistical regressions of leaf traits. New Phytol. 174, 626-636] suggested that the hydraulic limitation hypothesis (HLH) is the most plausible theory to explain the biophysical limits to maximum tree height and the decline in tree growth rate with age, the analysis is largely qualitative or based on statistical regression. Here we present an integrated biophysical model based on the principle that trees develop physiological compensations (e.g. the declined leaf water potential and the tapering of conduits with heights [West, G.B., Brown, J.H., Enquist, B.J., 1999. A general model for the structure and allometry of plant vascular systems. Nature 400, 664-667]) to resist the increasing water stress with height, the classical HLH and the biochemical limitations on photosynthesis [von Caemmerer, S., 2000. Biochemical Models of Leaf Photosynthesis. CSIRO Publishing, Australia]. The model has been applied to the tallest trees in the world (viz. Coast redwood (Sequoia sempervirens)). Xylem water potential, leaf carbon isotope composition, leaf mass to area ratio at different heights derived from the model show good agreements with the experimental measurements of Koch et al. [2004. The limits to tree height. Nature 428, 851-854]. The model also well explains the

  11. Assessment of the expression and role of the α1-nAChR subunit in efferent cholinergic function during the development of the mammalian cochlea.

    PubMed

    Roux, Isabelle; Wu, Jingjing Sherry; McIntosh, J Michael; Glowatzki, Elisabeth

    2016-08-01

    Hair cell (HC) activity in the mammalian cochlea is modulated by cholinergic efferent inputs from the brainstem. These inhibitory inputs are mediated by calcium-permeable nicotinic acetylcholine receptors (nAChRs) containing α9- and α10-subunits and by subsequent activation of calcium-dependent potassium channels. Intriguingly, mRNAs of α1- and γ-nAChRs, subunits of the "muscle-type" nAChR have also been found in developing HCs (Cai T, Jen HI, Kang H, Klisch TJ, Zoghbi HY, Groves AK. J Neurosci 35: 5870-5883, 2015; Scheffer D, Sage C, Plazas PV, Huang M, Wedemeyer C, Zhang DS, Chen ZY, Elgoyhen AB, Corey DP, Pingault V. J Neurochem 103: 2651-2664, 2007; Sinkkonen ST, Chai R, Jan TA, Hartman BH, Laske RD, Gahlen F, Sinkkonen W, Cheng AG, Oshima K, Heller S. Sci Rep 1: 26, 2011) prompting proposals that another type of nAChR is present and may be critical during early synaptic development. Mouse genetics, histochemistry, pharmacology, and whole cell recording approaches were combined to test the role of α1-nAChR subunit in HC efferent synapse formation and cholinergic function. The onset of α1-mRNA expression in mouse HCs was found to coincide with the onset of the ACh response and efferent synaptic function. However, in mouse inner hair cells (IHCs) no response to the muscle-type nAChR agonists (±)-anatoxin A, (±)-epibatidine, (-)-nicotine, or 1,1-dimethyl-4-phenylpiperazinium iodide (DMPP) was detected, arguing against the presence of an independent functional α1-containing muscle-type nAChR in IHCs. In α1-deficient mice, no obvious change of IHC efferent innervation was detected at embryonic day 18, contrary to the hyperinnervation observed at the neuromuscular junction. Additionally, ACh response and efferent synaptic activity were detectable in α1-deficient IHCs, suggesting that α1 is not necessary for assembly and membrane targeting of nAChRs or for efferent synapse formation in IHCs.

  12. Assessment of the expression and role of the α1-nAChR subunit in efferent cholinergic function during the development of the mammalian cochlea

    PubMed Central

    Wu (武靜靜), Jingjing Sherry; McIntosh, J. Michael; Glowatzki, Elisabeth

    2016-01-01

    Hair cell (HC) activity in the mammalian cochlea is modulated by cholinergic efferent inputs from the brainstem. These inhibitory inputs are mediated by calcium-permeable nicotinic acetylcholine receptors (nAChRs) containing α9- and α10-subunits and by subsequent activation of calcium-dependent potassium channels. Intriguingly, mRNAs of α1- and γ-nAChRs, subunits of the “muscle-type” nAChR have also been found in developing HCs (Cai T, Jen HI, Kang H, Klisch TJ, Zoghbi HY, Groves AK. J Neurosci 35: 5870–5883, 2015; Scheffer D, Sage C, Plazas PV, Huang M, Wedemeyer C, Zhang DS, Chen ZY, Elgoyhen AB, Corey DP, Pingault V. J Neurochem 103: 2651–2664, 2007; Sinkkonen ST, Chai R, Jan TA, Hartman BH, Laske RD, Gahlen F, Sinkkonen W, Cheng AG, Oshima K, Heller S. Sci Rep 1: 26, 2011) prompting proposals that another type of nAChR is present and may be critical during early synaptic development. Mouse genetics, histochemistry, pharmacology, and whole cell recording approaches were combined to test the role of α1-nAChR subunit in HC efferent synapse formation and cholinergic function. The onset of α1-mRNA expression in mouse HCs was found to coincide with the onset of the ACh response and efferent synaptic function. However, in mouse inner hair cells (IHCs) no response to the muscle-type nAChR agonists (±)-anatoxin A, (±)-epibatidine, (−)-nicotine, or 1,1-dimethyl-4-phenylpiperazinium iodide (DMPP) was detected, arguing against the presence of an independent functional α1-containing muscle-type nAChR in IHCs. In α1-deficient mice, no obvious change of IHC efferent innervation was detected at embryonic day 18, contrary to the hyperinnervation observed at the neuromuscular junction. Additionally, ACh response and efferent synaptic activity were detectable in α1-deficient IHCs, suggesting that α1 is not necessary for assembly and membrane targeting of nAChRs or for efferent synapse formation in IHCs. PMID:27098031

  13. Theoretical investigation on iodine oxides formation and their role in the production of atmospheric aerosols

    NASA Astrophysics Data System (ADS)

    Galvez, Óscar; Gomez, Pedro C.; Gomez-Martin, Juan C.; Saiz-Lopez, Alfonso; Pacios, Luis F.

    2013-04-01

    Atmospheric iodine has received considerable attention in the past two decades due to both its potential role in the catalytic destruction of ozone (1) and its contribution to the formation of ultrafine particles (2). Seaweeds, marine phytoplankton, and abiotic processes release iodocarbons and I2 to the atmosphere, which are photo-oxidized giving iodine oxides that polymerize to finally form iodine oxide particles (IOPs). In the last years, some laboratory studies have been carried out to investigate this process (see e.g. (3)), however the complete mechanism of formation of such particles and the role of water, and other condensable vapors, in this process have not yet been elucidated. In this context, quantum calculations could help to unravel essential steps of these processes and to evaluate relevant physicochemical properties that can be incorporated into atmospheric models. In this contribution, we show results of a theoretical study on different reactions that iodine oxides, in the presence of water, can undergo to form IOPs. Thermodynamic and kinetic properties of these reactions have been obtained at high level ab initio correlated calculations that included relativistic corrections. In these calculations, we have used a relativistic effective potential (REP) and REP-optimized basis sets for iodine atom developed in our group, which have previously been employed in a theoretical study about several iodinated species (4). (1) Saiz-Lopez, A.; Mahajan, A.S.; Salmon, R.A.; Bauguitte, J.B.; Jones, A.E.; Roscoe, H.K.; Plane, J.M.C. Science 2007, 317, 348-351 (2) O'Dowd, C.D.; Jimenez, J.L.; Bahreini, R.; Flagan, R.C.; Seinfeld, J.H.; Hämeri, K.; Pirjola, L.; Kulmala, M.; Jennings, S.G.; Hoffmann, T. Nature, 2002, 417, 632-636. (3) Saunders, R.W.; Kumar, R.; Gómez Martin, J.C.; Mahajan, A.S.; Murray, B.J.; Plane, J.M.C. Z. Phys. Chem. 2010, 224, 1095-1117. (4) Pacios, L.F.; Gálvez, O. J. Chem. Theory Comput., 2010, 6, 1738-1752.

  14. Quantum chemical investigation on the catalytic mechanism of vanadium iodoperoxidase and the iodination of common organic compounds

    NASA Astrophysics Data System (ADS)

    Gálvez, Óscar; Pacios, Luis F.

    2010-05-01

    , L.; Kulmala, M.; Jennings, S.G.; Hoffmann, T. Nature, 2002, 417, 632-636.

  15. Effects of Using Child Personas in the Development of a Digital Peer Support Service for Childhood Cancer Survivors.

    PubMed

    Wärnestål, Pontus; Svedberg, Petra; Lindberg, Susanne; Nygren, Jens M

    2017-05-18

    purposes. ©Pontus Wärnestål, Petra Svedberg, Susanne Lindberg, Jens M Nygren. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 18.05.2017.

  16. Shaping Civic Values in a Technological Age: Public and Private Challenges. Toward a National Dialogue. Conference Report and Discussion Guide on the Jennings Randolph Forum (2nd, Washington, District of Columbia, May 8-10, 1983).

    ERIC Educational Resources Information Center

    Eisenberg, Diane U., Ed.

    Designed as a resource for community program planners and teachers, this publication reports the highlights of a national conference on civic values in the technological age and provides guidelines for planning community discussions on the topic. Following an introduction, four sections of conference highlights are presented in a uniform format:…

  17. EDITORIAL: Focus on Quantum Information and Many-Body Theory

    NASA Astrophysics Data System (ADS)

    Eisert, Jens; Plenio, Martin B.

    2010-02-01

    and F Verstraete SIMULATION AND DYNAMICS A quantum differentiation of k-SAT instances B Tamir and G Ortiz Classical Ising model test for quantum circuits Joseph Geraci and Daniel A Lidar Exact matrix product solutions in the Heisenberg picture of an open quantum spin chain S R Clark, J Prior, M J Hartmann, D Jaksch and M B Plenio Exact solution of Markovian master equations for quadratic Fermi systems: thermal baths, open XY spin chains and non-equilibrium phase transition Tomaž Prosen and Bojan Žunkovič Quantum kinetic Ising models R Augusiak, F M Cucchietti, F Haake and M Lewenstein ENTANGLEMENT AND SPECTRAL PROPERTIES Ground states of unfrustrated spin Hamiltonians satisfy an area law Niel de Beaudrap, Tobias J Osborne and Jens Eisert Correlation density matrices for one-dimensional quantum chains based on the density matrix renormalization group W Münder, A Weichselbaum, A Holzner, Jan von Delft and C L Henley The invariant-comb approach and its relation to the balancedness of multipartite entangled states Andreas Osterloh and Jens Siewert Entanglement scaling of fractional quantum Hall states through geometric deformations Andreas M Läuchli, Emil J Bergholtz and Masudul Haque Entanglement versus gap for one-dimensional spin systems Daniel Gottesman and M B Hastings Entanglement spectra of critical and near-critical systems in one dimension F Pollmann and J E Moore Macroscopic bound entanglement in thermal graph states D Cavalcanti, L Aolita, A Ferraro, A García-Saez and A Acín Entanglement at the quantum phase transition in a harmonic lattice Elisabeth Rieper, Janet Anders and Vlatko Vedral Multipartite entanglement and frustration P Facchi, G Florio, U Marzolino, G Parisi and S Pascazio Entropic uncertainty relations—a survey Stephanie Wehner and Andreas Winter Entanglement in a spin system with inverse square statistical interaction D Giuliano, A Sindona, G Falcone, F Plastina and L Amico APPLICATIONS Time-dependent currents of one-dimensional bosons

  18. Non-native species impacts on pond occupancy by an anuran

    USGS Publications Warehouse

    Adams, Michael J.; Pearl, Christopher A.; Galvan, Stephanie; McCreary, Brome

    2011-01-01

    Non-native fish and bullfrogs (Lithobates catesbeianus; Rana catesbeiana) are frequently cited as factors contributing to the decline of ranid frogs in the western United States (Bradford 2005). This hypothesis is supported by studies showing competition with or predation by these introduced species (Kupferberg 1997, Kiesecker and Blaustein 1998, Lawler et al. 1999, Knapp et al. 2001) and studies suggesting a deficit of native frogs at sites occupied by bullfrogs or game fish (Hammerson 1982, Schwalbe and Rosen 1988, Fisher and Shaffer 1996, Adams 1999). Conversely, other studies failed to find a negative association between native ranids and bullfrogs and point out that presence of non-native species correlates with habitat alterations that could also contribute to declines of native species (Hayes and Jennings 1986; Adams 1999, 2000; Pearl et al. 2005). A criticism of these studies is that they may not detect an effect of non-native species if the process of displacement is at an early stage. We are not aware of any studies that have monitored a set of native frog populations to determine if non-native species predict population losses. Our objective was to study site occupancy trends in relation to non-native species for northern red-legged frogs (Rana aurora) on federal lands in the southern Willamette Valley, Oregon. We conducted a 5-yr monitoring study to answer the following questions about the status and trends of the northern red-legged frog: 1) What is the rate of local extinction (how often is a site that is occupied in year t unoccupied in year t+1) and what factors predict variation in local extinction? and 2) What is the rate of colonization (how often is a site that is unoccupied in year t occupied in year t+1) and what factors predict variation in colonization? The factors we hypothesized for local extinction were: 1) bullfrog presence, 2) bullfrogs mediated by wetland vegetation, 3) non-native fish (Centrarchidae), 4) non-native fish mediated by

  19. Titan's Carbon Isotopic Ratio: A Clue To Atmospheric Evolution?

    NASA Astrophysics Data System (ADS)

    Nixon, C. A.; Jennings, D. E.; Romani, P. N.; Jolly, A.; Teanby, N. A.; Irwin, P. G.; Bézard, B.; Vinatier, S.; Coustenis, A.; Flasar, F. M.

    2009-12-01

    In this presentation we describe the latest results to come from Cassini CIRS and ground-based telescopic measurements of Titan's 12C/13C ratio in atmospheric molecules, focusing on hydrocarbons. Previously, the Huygens GCMS instrument measured 12CH4/13CH4 to be 82±1 (Niemann et al., Nature, 438, 779-784, 2005), substantially and significantly lower than the VPDB inorganic Earth standard of 89.4. It is also at odds with measurements for the giant planets. Cassini CIRS infrared spectra have confirmed this enhancement in 13CH4, but also revealed that the ratio in ethane, the major photochemical product of methane photolysis, does not appear enhanced (90±7) (Nixon et al.. Icarus, 195, 778-791, 2008) and is compatible with the terrestrial and combined giant planet value (88±7, Sada et al., Ap. J., 472, p. 903-907, 1996). Recently-published results from spectroscopy using the McMath-Pierce telescope at Kitt Pitt (Jennings et al., JCP, 2009, in press) have confirmed this deviation between methane and ethane, and an explanation has been proposed. This invokes a kinetic isotope effect (KIE) in the abstraction of methane by ethynyl, a major ethane formation pathway, to preferentially partition 12C into ethane and leave an enhancement in atmospheric 13CH4 relative to the incoming flux from the reservoir. Modeling shows that a steady-state solution exists where the 12C/13C methane is decreased from the reservoir value by exactly the KIE factor (the ratio of 12CH4 to 13CH4 abstraction reaction rates): which is plausibly around 1.08, very close to the observed amount. However, a second solution exists in which we are observing Titan about ~1 methane lifetime after a major injection of methane into the atmosphere which is rapidly being eliminated. Updated measurements by Cassini CIRS of both the methane and ethane 12C/13C ratios will be presented, along with progress in interpreting this ratio. In addition, we summarize the 12C/13C measurements by CIRS in multiple other Titan

  20. Titan's methane clock

    NASA Astrophysics Data System (ADS)

    Nixon, C. A.; Jennings, D. E.; Romani, P. N.; Teanby, N. A.; Irwin, P. G. J.; Flasar, F. M.

    2010-04-01

    Measurements of the 12C/13C and D/H isotopic ratios in Titan's methane show intriguing differences from the values recorded in the giant planets. This implies that either (1) the atmosphere was differently endowed with material at the time of formation, or (2) evolutionary processes are at work in the moon's atmosphere - or some combination of the two. The Huygens Gas Chromatograph Mass Spectrometer Instrument (GCMS) found 12CH4/13CH4 = 82 +/- 1 (Niemann et al. 2005), some 7% lower than the giant planets' value of 88 +/- 7 (Sada et al. 1996), which closely matches the terrestrial inorganic standard of 89. The Cassini Composite Infrared Spectrometer (CIRS) has previously reported 12CH4/13CH4 of 77 +/-3 based on nadir sounding, which we now revise upwards to 80 +/- 4 based on more accurate limb sounding. The CIRS and GCMS results are therefore in agreement about an overall enrichment in 13CH4 of ~10%. The value of D/H in Titan's CH4 has long been controversial: historical measurements have ranged from about 8-15 x 10-5 (e.g. Coustenis et al. 1989, Coustenis et al. 2003). A recent measurement based on CIRS limb data by Bezard et al. (2007) puts the D/H in CH4 at (13 +/- 1) x 10-5, very much greater than in Jupiter and Saturn, ~2 x 10-5 (Mahaffy et al. 1998, Fletcher et al. 2009). To add complexity, the 12C/13C and D/H vary among molecules in Titan atmosphere, typically showing enhancement in D but depletion in 13C in the daughter species (H2, C2H2, C2H6), relative to the photochemical progenitor, methane. Jennings et al. (2009) have sought to interpret the variance in carbon isotopes as a Kinetic Isotope Effect (KIE), whilst an explanation for the D/H in all molecules remains elusive (Cordier et al. 2008). In this presentation we argue that evolution of isotopic ratios in Titan's methane over time forms a ticking 'clock', somewhat analogous to isotopic ratios in geochronology. Under plausible assumptions about the initial values and subsequent replenishment, various

  1. Titan's Gas Behavior During the South Pole Fall

    NASA Astrophysics Data System (ADS)

    Cottini, Valeria; Nixon, Conor A.; Achterberg, Richard K.; Jennings, Donald E.; Gorius, Nicolas; Irwin, Patrick G. J.

    2015-11-01

    Titan’s southern middle atmosphere has been showing several changes since the start of fall season in 2009. In 2012 a large cloud appeared [1], [2], [3], temperatures became very low and condensation and gas concentration at the South Pole increased [3], [4].In this work we will show the results of gas abundances retrievals in the South Pole and their latitudinal variation changes as the cold season evolved with time.We analyzed several Cassini Composite InfraRed Spectrometer (CIRS [5]) mid-infrared observations of the South Pole acquired during 2013-2014. The data coordinates were converted in order to be centered on the atmospheric pole and refer to the 1 mbar level and not to the surface. We first determine stratospheric temperatures from the same data and latitudes from the n4 band of methane centered around 1300 cm-1. We retrieve the temperature profiles applying a radiative transfer forward model combined with a non-linear optimal estimation inversion method [6]. We then retrieve the main gases abundances and track their variation with latitude using the same method.Latitudinal changes of the main Titan’s gases - HC3N, C4H2, C6H6, C2H2, C2H4, C3H8 and HCN - show different trends in the Southern polar regions over 2014, when winter was getting closer. We observe a ring-shape in some of the gas abundance distributions, with a local maximum peak around -75 deg of latitude. We also observe an increase of abundance of most of the gases toward the south pole, as seen previously in the North during the winter. The observed increase of benzene over the South Pole is definitely evident and strong. References: [1] West, R. A. et al. (2013) BAAS, 45, 305.03. [2] Jennings, D. E. et al. (2012) ApJ, 754, L3. [3] de Kok, R. et al. (2014), Nature, 514, 7520, 65-67. [4] Vinatier S. et al. (2015) Icarus, Volume 250, p. 95-115. [5] Flasar et al. (2004) Space Sci. Rev., 115, 169-297. [6] Irwin, P.G.J. et al. (2008) J. Quant. Spectrosc. Radiat. Trans., 109, 1136-1150.

  2. Exploring external time-dependent sources of H2O into Titan's atmosphere

    NASA Astrophysics Data System (ADS)

    Lara, Luisa-Maria; Lellouch, Emmanuel; González, Marta; Moreno, Raphael; Rengel, Miriam

    2014-05-01

    Recent observations (Cottini et al., 2012, and Moreno et al., 2012) and steady-state photochemical modelling (Moreno et al., 2012; Dobrijevic et al., 2014) indicate that the amounts of CO2 and H2O in Titan's stratosphere imply relatively inconsistent values of the OH/H2O input flux. Moreno et al. (2012) proposed that the oxygen source is time-variable, whereas Dobrijevic et al. (2014) arrived to the same conclusion of Moreno et al. (2012) that the HSO (Herschel Space Observatory) measured H2O profile is'inconsistent" with the CO2 abundance. Furthermore, Dobrijevic et al. (2014) also found that reconciliation was possible if abundances reported by Cottini et al. (2012) are correct instead, though in this situation and for an Enceladus source, their model tended to overpredict the thermospheric abundance of H2O , compared to the upper limit by Cui et al. (2009). We attempt to reconcile the H2O and CO2 observed profiles in Titan's atmosphere by considering several time-dependent scenarios for the infux/evolution of oxygen species. To explore this, we use a time-dependent photochemical model of Titan's atmosphere to calculate effective lifetimes and the response of Titan's oxygen compounds to changes in the oxygen input flux. We consider a time-variable Enceladus source, as well as the evolution of material delivered by a cometary impact. We will show results on effective H2O and CO2 effective lifetimes, on the feasibility of time-variable Enceladus source, and on an additional H2O loss-to-the-haze. Regarding CO2, we will analyse its production following a cometary impact. A summary on viable scenarios to explain the H2O / CO2 puzzle will be given. References Moreno, R., Lellouch, E., Lara, L. M., et al. 2012, Icarus, 221, 753. Cottini, V., Nixon, C. A., Jennings, D. E., et al. 2012, Icarus, 220, 855. Cui, J., Yelle, R. V., Vuitton, V., et al. 2009, Icarus, 200, 581. Dobrijevic, M., Hébrard, E., Loison, J., and Hickson, K. 2014, Icarus, 228, 324.

  3. Analysis of River Profiles in northwestern Bhutan

    NASA Astrophysics Data System (ADS)

    de Palézieux, Larissa; Leith, Kerry; Loew, Simon

    2017-04-01

    With large alluvial plains, narrow gorges, prominent knick points, and chains of terraces or cut-off ridges, the deeply-incised valleys in Bhutan reflect an environment of diverse erosional activity. Topography ranges from 97 m to 7570 m, with characteristic postglacial landscapes typically located above ca 4200 m. The lower latitudes below ca 3000 m show high relief and terraced or linear hillslopes indicative of a fluvial origin. Although full channel analyses in the region suggest significant local tectonic contributions to longitudinal river profiles (Adams et al., 2016), we develop a method to isolate rivers in an apparently homogeneous tectonic block in the mid- to upper- elevations. Profiles of rivers in this region show a consistent pattern with a marked topographic step covering 2000 m of elevation change within 10 km. Field observations of knick points, terraces and cut-off ridges associated with the step suggest a regionally consistent signal resulting from changes in relative uplift or erosion rate. Chi plots correlate well for all channels when the base level is chosen to isolate rivers below the main alluvial plain, suggesting similar fluvial erosion histories in upstream regions. Employing third order topographic derivatives (Minár et al., 2013), we identify low angle slope sections/plateaus corresponding to terraces and/or extrapolated ridges that project onto former valley floor levels. Employing similar methods as those used to correlate fluvial knickpoints, these will be used to test for regionally consistent changes in fluvial and hillslope activity that may be tied to major tectonic or climatic changes. REFERENCES Adams, B., Whipple, K. X., Hodges, K. V. & Heimsath, A. M. 2016: In situ development of high-elevation, low-relief landscapes via duplex deformation in the Eastern Himalayan hinterland, Bhutan, in Journal of Geophysical Research: Earth Surface, 925-938. Minár, J., Jenčo, M., Evans, I. S., Minár, J., Kadlec, M., Krcho, J., Pacina

  4. Cogenerating fluency in urban science classrooms

    NASA Astrophysics Data System (ADS)

    Lavan, Sarah-Kate

    This critical ethnographic study employed the use of cogenerative dialogue (Roth & Tobin, 2002) as a means to allow participants of a science classroom to reflect on and transform classroom structures while at the same time create opportunities for all stakeholders to develop collective responsibility for teaching and learning. The research was situated in a science classroom in an inner city charter high school that was both a challenging place for the teacher (Jen Beers) and an oppressive place for the students as all struggled to reconcile issues related to power hierarchies and significant differences in social and cultural histories. As a result, cultural misinterpretations and the undervaluing of students' cultural capital served as a foundation for learning. This study examined the various fields and forms of practice that created opportunities for refining teaching practices and at the same time afforded the development of collective responsibility by addressing the roles, identities and agency of all classroom participants. Specifically, I asked the following questions: (1) How can co-generative dialogue can be used to involve all classroom participants in creating a learning community? (2) How does this shape the identities and roles of the participants who were involved? and (3) How do the changed roles and practices lead toward science fluency? The framework of cultural sociology, specifically the dialectical relationship of structure and agency, interaction ritual theory (Collins, 2003) and research on dispositions (Boykin, 1986), provided analytic tools to investigate the practices of the various stakeholders and the classroom structures as well as the historical and cultural contexts surrounding them. Multiple data resources such as field notes, videotape, interviews and artifacts were drawn on from two fields (the science classroom and cogenerative dialogues) to elicit and support findings at micro, meso and macroscopic levels. The major findings of

  5. A Test of the Optimality Approach to Modelling Canopy gas Exchange by Natural Vegetation

    NASA Astrophysics Data System (ADS)

    Schymanski, S. J.; Sivapalan, M.; Roderick, M. L.; Beringer, J.; Hutley, L. B.

    2005-12-01

    Journal of Wildland Fire 12(3-4): 333-340. - Cowan, I. R. and G. D. Farquhar (1977). Stomatal Function in Relation to Leaf Metabolism and Environment. Integration of activity in the higher plant. D. H. Jennings. Cambridge, Cambridge University Press: 471-505. - von Caemmerer, S. (2000). Biochemical Models of Leaf Photosynthesis. Collingwood, CSIRO Publishing.

  6. Effect of Exposure to Atmospheric Ultrafine Particles on Production of Free Fatty Acids and Lipid Metabolites in the Mouse Small Intestine

    PubMed Central

    Li, Rongsong; Navab, Kaveh; Hough, Greg; Daher, Nancy; Zhang, Min; Mittelstein, David; Lee, Katherine; Pakbin, Payam; Saffari, Arian; Bhetraratana, May; Sulaiman, Dawoud; Beebe, Tyler; Wu, Lan; Jen, Nelson; Wine, Eytan; Tseng, Chi-Hong; Araujo, Jesus A.; Fogelman, Alan; Sioutas, Constantinos; Navab, Mohamed

    2014-01-01

    Background: Exposure to ambient ultrafine particulate matter (UFP) is a well-recognized risk factor for cardiovascular and respiratory diseases. However, little is known about the effects of air pollution on gastrointestinal disorders. Objective: We sought to assess whether exposure to ambient UFP (diameter < 180 nm) increased free fatty acids and lipid metabolites in the mouse small intestine. Methods: Ldlr-null mice were exposed to filtered air (FA) or UFP collected at an urban Los Angeles, California, site that was heavily affected by vehicular emissions; the exposure was carried out for 10 weeks in the presence or absence of D-4F, an apolipoprotein A-I mimetic peptide with antioxidant and anti-inflammation properties on a high-fat or normal chow diet. Results: Compared with FA, exposure to UFP significantly increased intestinal hydroxyeicosatetraenoic acids (HETEs), including 15-HETE, 12-HETE, 5-HETE, as well as hydroxyoctadecadienoic acids (HODEs), including 13-HODE and 9-HODE. Arachidonic acid (AA) and prostaglandin D2 (PGD2) as well as some of the lysophosphatidic acids (LPA) in the small intestine were also increased in response to UFP exposure. Administration of D-4F significantly reduced UFP-mediated increase in HETEs, HODEs, AA, PGD2, and LPA. Although exposure to UFP further led to shortened villus length accompanied by prominent macrophage and neutrophil infiltration into the intestinal villi, administration of D-4F mitigated macrophage infiltration. Conclusions: Exposure to UFP promotes lipid metabolism, villus shortening, and inflammatory responses in mouse small intestine, whereas administration of D-4F attenuated these effects. Our findings provide a basis to further assess the mechanisms underlying UFP-mediated lipid metabolism in the digestive system with clinical relevance to gut homeostasis and diseases. Citation: Li R, Navab K, Hough G, Daher N, Zhang M, Mittelstein D, Lee K, Pakbin P, Saffari A, Bhetraratana M, Sulaiman D, Beebe T, Wu L, Jen

  7. Quality control, analysis and secure sharing of Luminex® immunoassay data using the open source LabKey Server platform

    PubMed Central

    2013-01-01

    Background Immunoassays that employ multiplexed bead arrays produce high information content per sample. Such assays are now frequently used to evaluate humoral responses in clinical trials. Integrated software is needed for the analysis, quality control, and secure sharing of the high volume of data produced by such multiplexed assays. Software that facilitates data exchange and provides flexibility to perform customized analyses (including multiple curve fits and visualizations of assay performance over time) could increase scientists’ capacity to use these immunoassays to evaluate human clinical trials. Results The HIV Vaccine Trials Network and the Statistical Center for HIV/AIDS Research and Prevention collaborated with LabKey Software to enhance the open source LabKey Server platform to facilitate workflows for multiplexed bead assays. This system now supports the management, analysis, quality control, and secure sharing of data from multiplexed immunoassays that leverage Luminex xMAP® technology. These assays may be custom or kit-based. Newly added features enable labs to: (i) import run data from spreadsheets output by Bio-Plex Manager™ software; (ii) customize data processing, curve fits, and algorithms through scripts written in common languages, such as R; (iii) select script-defined calculation options through a graphical user interface; (iv) collect custom metadata for each titration, analyte, run and batch of runs; (v) calculate dose–response curves for titrations; (vi) interpolate unknown concentrations from curves for titrated standards; (vii) flag run data for exclusion from analysis; (viii) track quality control metrics across runs using Levey-Jennings plots; and (ix) automatically flag outliers based on expected values. Existing system features allow researchers to analyze, integrate, visualize, export and securely share their data, as well as to construct custom user interfaces and workflows. Conclusions Unlike other tools tailored for

  8. Olivine-hosted melt inclusions record efficient mixing of mantle melts in continental flood basalt provinces

    NASA Astrophysics Data System (ADS)

    Jennings, E. S.; Gibson, S. A.; Maclennan, J.; Heinonen, J. S.

    2017-12-01

    the deepest, hottest and lowest viscosity magma of all the samples considered. [1] Jennings E. S., Gibson S. A., Maclennan J. and Heinonen J. S. (2017) Deep mixing of mantle melts beneath continental flood basalt provinces: Constraints from olivine-hosted melt inclusions in primitive magmas. Geochimica et Cosmochimica Acta 196, 36-57.

  9. Reaching the Next Generation of College Students via Their Digital Devices.

    NASA Astrophysics Data System (ADS)

    Whitmeyer, S. J.; De Paor, D. G.; Bentley, C.

    2015-12-01

    Cooper, Mladen Dordevic, Marissa Dudek, Brandon Fitzwater, Bridget Gomez, Tyler Hansen, Paul Karabinos, Terry Pavlis, Jen Piatek, Alan Pitts, Robin Rohrback, Bill Richards, Caroline Robinson, Jeff Rollins, Jeff Ryan, Ron Schott, Kristen St. John, and Barb Tewksbury. Supported by NSF DUE 1323419 and by Google Geo Curriculum Awards.

  10. Hydrologic data for urban studies in the Houston, Texas, metropolitan area, 1979

    USGS Publications Warehouse

    Liscum, Fred; Weigel, Jay F.; Bruchmiller, J.P.

    1982-01-01

    Hydrologic investigations of urban watersheds in Texas were begun by the U.S. Geological Survey in 1954. Studies are now in progress in Austin, Houston, and San Antonio.The U.S. Geological Survey, in cooperation with the city of Houston, began studies in the Houston metropolitan area in 1964. The program was expanded in 1968 to include collection of water-quality data. The objectives of the Houston urban-hydrology study are as follows:To determine, on the basis of historical data and hydro!ogic analyses, the magnitude and frequency of flood peaks and flood volumes.To determine the effect of urban development on flood peaks and volumes.To ascertain the variation in water quality for different flow conditions and different seasons.This report, the sixteenth in a series of reports to be published annually, is primarily applicable to objective 2. The report presents hydro!ogic data collected in the Houston urban area for the 1979 water year (October 1, 1978 to September 30, 1979).A report by Johnson and Sayre (1973) utilized records collected from 1965 to 1969 to make a study of the effects of urbanization on floods in the Houston area. The report also summarizes various basin parameters. A report by Waddell, Massey, and Jennings (1979) presents data on computed runoff from the Houston area and computed concentrations and loads of selected waterquality constituents combined in the inflow to Galveston Bay. The study utilized a variation of the "STORM" model developed by the Hydro!ogic Engineering Center of the U.S. Army Corps of Engineers. A report prepared by Li scum and Massey (1980) presents a technique for estimating the magnitude and frequency of floods in the Houston area from drainage areas, bank-full conveyance, and percentage of urban development.A definition of terms related to streamflow, water quality, and other hydrologic data, as used in this report, are defined in "U.S. Geological Survey, Water-resources data for Texas, volume 2, 1979."To facilitate the

  11. Mitochondria-localized caveolin in adaptation to cellular stress and injury

    PubMed Central

    Fridolfsson, Heidi N.; Kawaraguchi, Yoshitaka; Ali, Sameh S.; Panneerselvam, Mathivadhani; Niesman, Ingrid R.; Finley, J. Cameron; Kellerhals, Sarah E.; Migita, Michael Y.; Okada, Hideshi; Moreno, Ana L.; Jennings, Michelle; Kidd, Michael W.; Bonds, Jacqueline A.; Balijepalli, Ravi C.; Ross, Robert S.; Patel, Piyush M.; Miyanohara, Atsushi; Chen, Qun; Lesnefsky, Edward J.; Head, Brian P.; Roth, David M.; Insel, Paul A.; Patel, Hemal H.

    2012-01-01

    We show here that the apposition of plasma membrane caveolae and mitochondria (first noted in electron micrographs >50 yr ago) and caveolae-mitochondria interaction regulates adaptation to cellular stress by modulating the structure and function of mitochondria. In C57Bl/6 mice engineered to overexpress caveolin specifically in cardiac myocytes (Cav-3 OE), localization of caveolin to mitochondria increases membrane rigidity (4.2%; P<0.05), tolerance to calcium, and respiratory function (72% increase in state 3 and 23% increase in complex IV activity; P<0.05), while reducing stress-induced generation of reactive oxygen species (by 20% in cellular superoxide and 41 and 28% in mitochondrial superoxide under states 4 and 3, respectively; P<0.05) in Cav-3 OE vs. TGneg. By contrast, mitochondrial function is abnormal in caveolin-knockout mice and Caenorhabditis elegans with null mutations in caveolin (60% increase free radical in Cav-2 C. elegans mutants; P<0.05). In human colon cancer cells, mitochondria with increased caveolin have a 30% decrease in apoptotic stress (P<0.05), but cells with disrupted mitochondria-caveolin interaction have a 30% increase in stress response (P<0.05). Targeted gene transfer of caveolin to mitochondria in C57Bl/6 mice increases cardiac mitochondria tolerance to calcium, enhances respiratory function (increases of 90% state 4, 220% state 3, 88% complex IV activity; P<0.05), and decreases (by 33%) cardiac damage (P<0.05). Physical association and apparently the transfer of caveolin between caveolae and mitochondria is thus a conserved cellular response that confers protection from cellular damage in a variety of tissues and settings.—Fridolfsson, H. N., Kawaraguchi, Y., Ali, S. S., Panneerselvam, M., Niesman, I. R., Finley, J. C., Kellerhals, S. E., Migita, M. Y., Okada, H., Moreno, A. L., Jennings, M., Kidd, M. W., Bonds, J. A., Balijepalli, R. C., Ross, R. S., Patel, P. M., Miyanohara, A., Chen, Q., Lesnefsky, E. J., Head, B. P., Roth, D

  12. Quality control, analysis and secure sharing of Luminex® immunoassay data using the open source LabKey Server platform.

    PubMed

    Eckels, Josh; Nathe, Cory; Nelson, Elizabeth K; Shoemaker, Sara G; Nostrand, Elizabeth Van; Yates, Nicole L; Ashley, Vicki C; Harris, Linda J; Bollenbeck, Mark; Fong, Youyi; Tomaras, Georgia D; Piehler, Britt

    2013-04-30

    Immunoassays that employ multiplexed bead arrays produce high information content per sample. Such assays are now frequently used to evaluate humoral responses in clinical trials. Integrated software is needed for the analysis, quality control, and secure sharing of the high volume of data produced by such multiplexed assays. Software that facilitates data exchange and provides flexibility to perform customized analyses (including multiple curve fits and visualizations of assay performance over time) could increase scientists' capacity to use these immunoassays to evaluate human clinical trials. The HIV Vaccine Trials Network and the Statistical Center for HIV/AIDS Research and Prevention collaborated with LabKey Software to enhance the open source LabKey Server platform to facilitate workflows for multiplexed bead assays. This system now supports the management, analysis, quality control, and secure sharing of data from multiplexed immunoassays that leverage Luminex xMAP® technology. These assays may be custom or kit-based. Newly added features enable labs to: (i) import run data from spreadsheets output by Bio-Plex Manager™ software; (ii) customize data processing, curve fits, and algorithms through scripts written in common languages, such as R; (iii) select script-defined calculation options through a graphical user interface; (iv) collect custom metadata for each titration, analyte, run and batch of runs; (v) calculate dose-response curves for titrations; (vi) interpolate unknown concentrations from curves for titrated standards; (vii) flag run data for exclusion from analysis; (viii) track quality control metrics across runs using Levey-Jennings plots; and (ix) automatically flag outliers based on expected values. Existing system features allow researchers to analyze, integrate, visualize, export and securely share their data, as well as to construct custom user interfaces and workflows. Unlike other tools tailored for Luminex immunoassays, LabKey Server

  13. New SI-traceable reference gas mixtures for sulfur hexafluoride (SF6) at the pmol/mol level using static and dynamic preparation methods and comparison to existing scales

    NASA Astrophysics Data System (ADS)

    Wyss, Simon A.; Guillevic, Myriam; Vicar, Martin; Nieuwenkamp, Gerard; Vollmer, Martin K.; Pascale, Céline; Reimann, Stefan; Niederhauser, Bernhard; Emmenegger, Lukas

    2017-04-01

    near-ambient amount fraction for SF6, without extensive static dilutions. [1] Benjamin R. Miller, Ray F. Weiss, Peter K. Salameh, Toste Tanhua, Brian R. Greally, Jens Mühle, Peter G. Simmonds, Anal. Chem., 2008, 80, 1536.

  14. Physiology-Based Modeling May Predict Surgical Treatment Outcome for Obstructive Sleep Apnea

    PubMed Central

    Li, Yanru; Ye, Jingying; Han, Demin; Cao, Xin; Ding, Xiu; Zhang, Yuhuan; Xu, Wen; Orr, Jeremy; Jen, Rachel; Sands, Scott; Malhotra, Atul; Owens, Robert

    2017-01-01

    Apnea Treatment on Physiology Traits in Chinese Patients With Obstructive Sleep Apnea; Identifier: NCT02696629; URL: https://clinicaltrials.gov/show/NCT02696629 Citation: Li Y, Ye J, Han D, Cao X, Ding X, Zhang Y, Xu W, Orr J, Jen R, Sands S, Malhotra A, Owens R. Physiology-based modeling may predict surgical treatment outcome for obstructive sleep apnea. J Clin Sleep Med. 2017;13(9):1029–1037. PMID:28818154

  15. In Silico Analysis of Six Known Leishmania major Antigens and In Vitro Evaluation of Specific Epitopes Eliciting HLA-A2 Restricted CD8 T Cell Response

    PubMed Central

    Seyed, Negar; Zahedifard, Farnaz; Safaiyan, Shima; Gholami, Elham; Doustdari, Fatemeh; Azadmanesh, Kayhan; Mirzaei, Maryam; Saeedi Eslami, Nasir; Khadem Sadegh, Akbar; Eslami far, Ali; Sharifi, Iraj; Rafati, Sima

    2011-01-01

    Background As a potent CD8+ T cell activator, peptide vaccine has found its way in vaccine development against intracellular infections and cancer, but not against leishmaniasis. The first step toward a peptide vaccine is epitope mapping of different proteins according to the most frequent HLA types in a population. Methods and Findings Six Leishmania (L.) major-related candidate antigens (CPB,CPC,LmsTI-1,TSA,LeIF and LPG-3) were screened for potential CD8+ T cell activating 9-mer epitopes presented by HLA-A*0201 (the most frequent HLA-A allele). Online software including SYFPEITHI, BIMAS, EpiJen, Rankpep, nHLApred, NetCTL and Multipred were used. Peptides were selected only if predicted by almost all programs, according to their predictive scores. Pan-A2 presentation of selected peptides was confirmed by NetMHCPan1.1. Selected peptides were pooled in four peptide groups and the immunogenicity was evaluated by in vitro stimulation and intracellular cytokine assay of PBMCs from HLA-A2+ individuals recovered from L. major. HLA-A2− individuals recovered from L. major and HLA-A2+ healthy donors were included as control groups. Individual response of HLA-A2+ recovered volunteers as percent of CD8+/IFN-γ+ T cells after in vitro stimulation against peptide pools II and IV was notably higher than that of HLA-A2− recovered individuals. Based on cutoff scores calculated from the response of HLA-A2− recovered individuals, 31.6% and 13.3% of HLA-A2+ recovered persons responded above cutoff in pools II and IV, respectively. ELISpot and ELISA results confirmed flow cytometry analysis. The response of HLA-A2− recovered individuals against peptide pools I and III was detected similar and even higher than HLA-A2+ recovered individuals. Conclusion Using in silico prediction we demonstrated specific response to LmsTI-1 (pool II) and LPG-3- (pool IV) related peptides specifically presented in HLA-A*0201 context. This is among the very few reports mapping L. major epitopes for

  16. Reinstatement after human feature-positive discrimination learning.

    PubMed

    Franssen, Mathijs; Claes, Nathalie; Vervliet, Bram; Beckers, Tom; Hermans, Dirk; Baeyens, Frank

    2017-04-01

    In two experiments, using an online conditioned suppression task, we investigated the possibility of reinstatement of extinguished feature-target compound presentations after sequential feature-positive discrimination training in humans. Furthermore, given a hierarchical account of Pavlovian modulation (e.g., Bonardi, 1998; Bonardi and Jennings, 2009), we predicted A-US reinstatement to be stronger than US-only reinstatement. In Experiment 1, participants learned a sequential feature-positive discrimination (X→A + |A - ), which was subsequently extinguished (X→A - ). During the following reinstatement phase, group US-only received US-only presentations (not signalled), group A-US received A-US presentations, and the Control group received exposure to the context, but no CSs or USs, for an equal amount of time. Reinstatement of differential X→A/A responding was observed in the US-only group but not in the Control or A-US groups. Although differential X→A/A responding was not significant in group A-US, responding to the X→A compound was significantly stronger compared to that in group US-only. Hence, it could be the case the group A-US showed stronger reinstatement, but that differential responding was abolished due to excitation gained by A. Experiment 2 was set up to circumvent the acquired excitation of A by testing transfer of the feature after A-US reinstatement to a different target, B. Participants acquired two discriminations, X→A/A and Y→B/B, of which X→A was then extinguished. Subsequently, group A-US received reinforced presentations of A during a reinstatement phase while group Control received exposure to the context. Final testing of the novel X→B compound was hypothesized to show higher responding in group A-US than in group Control, but findings of this approach were limited due to acquired equivalence and/or perceptual factors causing a secondary extinction effect. We conclude to have obtained clear evidence in favour of

  17. [The establishment and application of internal quality control system for real-time quantitative PCR detection of BCR-ABL (P210) transcript levels].

    PubMed

    Zhong, C Q; He, N; Hua, M Q; Wei, X D; Ma, D X; Ji, C Y

    2016-09-14

    Objective: To set internal quality control system of BCR-ABL (P210) transcript levels for real-time quantitative PCR (RQ-PCR). Methods: Using K562 cells and HL-60 cells, we prepared high- and low-level BCR-ABL internal quality control substance. The BCR-ABL (P210) transcript levels of internal quality control substance have been determined for 184 times together with clinical samples from August 2013 to October 2015. The slope rate, intercept and correlation coefficient of standard curve were calculated according to different reagent lots (lots number 20130303, 20131212, 20140411 and 20150327 are called R1、R2、R3 and R4 for short respectively), and the detection results of quality control substance were calculated according to different reagent lots and quality control substance lots (lots number 20130725, 20140611 are called Q1、Q2 for short respectively). Then the results were analyzed by Levey-Jennings quality control chart combined with Westgard multi-rules theory. Results: ①We analyzed the slope rate and intercept of standard curve. Fifty-three times of the R1 reagent detection, 80 times of the R3 reagent detection and 14 times of the R4 reagent detection were all under control. For 37 times detection of R2 reagent, the slope rate was out of control for 6 times. It was lower than x - s for the 2-8 tests and upper the average for the 12-37 tests. The intercept was out of control for 9 times, upper the x + s for the 1-8 tests and lower the average for the 12-37 tests. ② According to the detection results of quality control substance, for Q1 quality control substance, 49 tests by R1 reagent were under control, and 1 out of 23 tests by R2 reagent was out of control. For Q2 quality control substance, 14 tests by R2 reagent detection, 72 tests by R3 reagent detection and 14 tests by R4 reagent were all under control. Conclusion: The preparation of high- and low-level quality control substance using K562 and HL-60 cells was convenient and the detection

  18. Water on the Early M Supergiant Stars α Orionis and μ Cephei

    NASA Astrophysics Data System (ADS)

    Tsuji, T.

    2000-08-01

    We reanalyze the spectra of α Ori (M2 Iab) and μ Cep (M2 Ia) observed with the balloon-borne telescope Stratoscope II more than 35 years ago, and we confirm the presence of water in these early M supergiant stars. This identification was first proposed by the Stratoscope observers themselves (Woolf, Schwarzschild, and Rose in 1964; and Danielson, Woolf, and Gaustad in 1965), but this important discovery was overlooked for a long time without any follow-up observation. Consequently, this finding has so far had little influence on the theory of the atmosphere of red supergiant stars. A reason for this may be due to an early criticism by Wing and Spinrad, who suggested CN instead of H2O for the spectral features observed by Stratoscope II. This alternative proposition has more easily been accepted since CN has widely been observed from the Sun to red supergiants, while H2O has been observed only in very cool stars such as Mira variables. In fact, we confirm that the self-consistent photospheric model of the early M supergiants shows CN bands but no H2O band in the near-infrared. Nevertheless, we find that the contribution of CN is only minor and that H2O should be the dominant absorber for the 1.4 and 1.9 μm features on the Stratoscope spectra of α Ori and μ Cep, a conclusion opposite to that of Wing and Spinrad. The observed spectra can best be interpreted by the water gas with the column density of the order of 1020 cm-2 and temperature about 1500+/-500 K, but they cannot be originating in the photosphere. We suggest a possible presence of a gaseous component not as hot as the chromosphere but warmer than the cool expanding envelope. On the other hand, we notice that the mid-infrared pure-rotation lines of H2O recently discovered on Betelgeuse (α Ori) and Antares (α Sco) by Jennings and Sada may partly be originating in the photosphere, even though the larger part should again be nonphotospheric in origin. Thus, the presence of water possibly originating in

  19. General Practitioners' Perspective on eHealth and Lifestyle Change: Qualitative Interview Study.

    PubMed

    Brandt, Carl Joakim; Søgaard, Gabrielle Isidora; Clemensen, Jane; Sndergaard, Jens; Nielsen, Jesper Bo

    2018-04-17

    optimize processes and not hinder other treatments. Looking ahead, education of GPs and recognizing patients' ability and preference to use eHealth with regard to a healthy living are needed. ©Carl Joakim Brandt, Gabrielle Isidora Søgaard, Jane Clemensen, Jens Sndergaard, Jesper Bo Nielsen. Originally published in JMIR Mhealth and Uhealth (http://mhealth.jmir.org), 17.04.2018.

  20. Uranium in surface soils: an easy-and-quick assay combining X-ray diffraction and fluorescence qualitative data

    NASA Astrophysics Data System (ADS)

    Figueiredo, M. O.; Silva, T. P.; Batista, M. J.; Leote, J.; Ferreira, M. L.; Limpo, V.

    2009-04-01

    discovery and valorisation (in Portuguese). Internal Rept., JEN, 20 pp. [3] http://www.naturtejo.com [4] J.A. Davis et al. (2006) Processes affecting transport of uranium in a suboxic aquifer. Phys. Chem. of the Earth 31, 548-555. [5] Y. Arai et al. (2007) Spectroscopic evidence for uranium bearing precipitates in Vadose zone sediments at the Hanford 300-Area site. Environ. Sci. Technol. 41, 4633-4639. [6] A. Kremleva, S. Krüger & N. Rösch (2008) Density functional model studies of uranyl adsorption on (001) surfaces of kaolinite. Langmuir 24, 9515-9524.

  1. Domiciliary VR-Based Therapy for Functional Recovery and Cortical Reorganization: Randomized Controlled Trial in Participants at the Chronic Stage Post Stroke.

    PubMed

    Ballester, Belén Rubio; Nirme, Jens; Camacho, Irene; Duarte, Esther; Rodríguez, Susana; Cuxart, Ampar; Duff, Armin; Verschure, Paul F M J

    2017-08-07

    findings suggest that, in chronic stages, remote delivery of customized VR-based motor training promotes functional gains that are accompanied by neuroplastic changes. International Standard Randomized Controlled Trial Number NCT02699398 (Archived by ClinicalTrials.gov at https://clinicaltrials.gov/ct2/show/NCT02699398?term=NCT02699398&rank=1). ©Belén Rubio Ballester, Jens Nirme, Irene Camacho, Esther Duarte, Susana Rodríguez, Ampar Cuxart, Armin Duff, Paul F.M.J. Verschure. Originally published in JMIR Serious Games (http://games.jmir.org), 07.08.2017.

  2. Effects of Microbial and Phosphate Amendments on the Bioavailability of Lead (Pb) in Shooting Range Soil

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Brigmon, Robin; Wilson, Christina; Knox, Anna

    Heavy metals including lead (Pb) are released continually into the environment as a result of industrial, recreational, and military activities. Lead ranked number two on the CERCLA Priority List of Hazardous Substances and was identified as a major hazardous chemical found on 47% of USEPA's National Priorities List sites (Hettiarachchi and Pierzynski 2004). In-situ remediation of lead (Pb) contaminated soils may be accomplished by changing the soil chemistry and structure with the application of microbial and phosphate amendments. Soil contaminated with lead bullets was collected from the surface of the berm at Savannah River Site (SRS) Small Arms Training Academymore » (SATA) in Aiken, SC. While uncontaminated soils typically have Pb levels ranging from 2 to 200 mg/kg (Berti et al. 1998), previous analysis show Pb levels of the SATA berm to reach 8,673 mg/kg. Biosurfactants are surface-active compounds naturally produced by soil bacteria that can bind metals. Biosurfactants have a wide variety of chemical structures that reduce interfacial surface tensions (Jennings and Tanner 2000) and have demonstrated efficient metal complexion (Lin 1996). Biosurfactants also have the potential to change the availability of natural organic matter (Strong-Gunderson 1995). Two types of bacteria, Alcaligenes piechaudii and Pseudomonas putida, were employed as amendments based on their ability to produce biosurfactants and survive in metal-contaminated soils. Apatites (calcium phosphate compounds) are important in the formation of Pb phosphates. Pb phosphates form rapidly when phosphate is available and are the most stable environmental form of lead in soil (Ruby et al.1998). Pyromorphites in particular remain insoluble under a wide range of environmental conditions (Zhang et al. 1998). The three apatites evaluated in the current study were North Carolina apatite (NCA), Florida apatite (FA), and biological apatite (BA). BA is ground fish bone that has few impurities such as As

  3. Water vapor on Titan: the stratospheric vertical profile from Cassini/CIRS infrared spectra

    NASA Astrophysics Data System (ADS)

    Cottini, V.; Jennings, D. E.; Nixon, C. A.; Anderson, C. M.; Gorius, N.; Bjoraker, G. L.; Coustenis, A.; Achterberg, R. K.; Teanby, N. A.; de Kok, R.; Irwin, P. G. J.; Bézard, B.; Lellouch, E.; Flasar, F. M.; Bampasidis, G.

    2012-04-01

    Water vapor in Titan’s middle atmosphere has previously been detected only by disk-average observations from the Infrared Space Observatory (Coustenis et al., 1998). We report here the successful detection of stratospheric water vapor using the Cassini Composite Infrared Spectrometer (CIRS, Flasar et al., 2004) following an earlier null result (de Kok et al., 2007a). CIRS senses water emissions in the far-infrared spectral region near 50 microns, which we have modeled using two independent radiative transfer and inversion codes (NEMESIS, Irwin et al 2008 and ART, Coustenis et al., 2010). From the analysis of nadir spectra we have derived a mixing ratio of (0.14 ± 0.05) ppb at 100 km, corresponding to a column abundance of approximately (3.7 ± 1.3) × 10^14 mol/cm2. Using limb observations, we obtained mixing ratios of (0.13 ± 0.04) ppb at 125 km and (0.45 ± 0.15) ppb at 225 km of altitude, confirming that the water abundance has a positive vertical gradient as predicted by photochemical models. In the latitude range (80˚S - 30˚N) we see no evidence for latitudinal variations in these abundances within the error bars. References: Coustenis, A.; Salama, A.; Lellouch, E.; Encrenaz, Th.; Bjoraker, G. L.; Samuelson, R. E.; de Graauw, Th.; Feuchtgruber, H.; Kessler, M. F., 1998. Evidence for water vapor in Titan's atmosphere from ISO/SWS data. Astronomy and Astrophysics, v.336, p.L85-L89 Coustenis, A.; Jennings, D. E.; Nixon, C. A.; Achterberg, R. K.; Lavvas, P.; Vinatier, S.; Teanby, N. A.; Bjoraker, G. L.; Carlson, R. C.; Piani, L.; Bampasidis, G.; Flasar, F. M.; Romani, P. N., 2010. Titan trace gaseous composition from CIRS at the end of the Cassini-Huygens prime mission. Icarus, Volume 207, Issue 1, p. 461-476. de Kok, R.; Irwin, P. G. J.; Teanby, N. A.; Lellouch, E.; Bézard, B.; Vinatier, S.; Nixon, C. A.; Fletcher, L.; Howett, C.; Calcutt, S. B.; Bowles, N. E.; Flasar, F. M.; Taylor, F. W. , 2007a. Oxygen compounds in Titan's stratosphere as observed by

  4. PREFACE: The IX Mexican Workshop on Particles and Fields

    NASA Astrophysics Data System (ADS)

    Amore, Paolo; Aranda, Alfredo; Bashir, Adnan; Mondragón, Myriam; Raya, Alfredo

    2006-05-01

    The IX Mexican Workshop on Particles and Fields was held in the beautiful city of Colima, in the South-West of Mexico, from 17-22 November 2003. The proceedings of the Workshop were delayed due to problems with a previous publisher, we are very grateful that Journal of Physics: Conference Series kindly agreed to publish the proceedings rapidly at this late stage. The Workshop aimed to cover, through invited lectures delivered by internationally known experts, the most recent developments in the field. There was also a series of short seminars as well as a poster session, which allowed the whole community to participate with their most recent research results. A special session was dedicated to awarding the Division Medal to Professor Benjamin Grinstein, from The University of California, San Diego, for his outstanding contributions to the field. This volume contains the written version of the material presented at the Workshop. The Workshop was attended by more than 100 participants, including faculty members, postdocs and graduate students. It was organized by the Particles and Fields Division of the Mexican Physical Society, and generously sponsored by several institutions: Universidad de Colima, Universidad Nacional Autónoma de México, Universidad Michoacana de San Nicolás Hidalgo, Centro de Investigaciones y Estudios Avanzados del IPN (CINVESTAV), Consejo Nacional de Ciencia y Tecnología (Conacyt). The Local Organizing Committee was integrated by Paolo Amore, Alfredo Aranda, Carlos Moisés Hernóndez Suórez (Director of the Physics Faculty), Arturo Gonzólez Larios, Enrique Farías Martínez, and Myriam Cruz Calvario, all from the University of Colima. The members of the National Organizing Committee were Adnan Bashir (IFM-UMSHN), Jens Erler (IF-UNAM), Heriberto Castilla Valdés (CINVESTAV-U.Zacatenco), Gabriel López Castro (CINVESTAV-U.Zacatenco), Myriam Mondragón (IF-UNAM) and Luis Villaseñ or (IFM-UMSHN). We gratefully acknowledge the help given by

  5. "The role of different stigma perceptions in treatment seeking and dropout among active duty military personnel": Correction to Britt et al. (2015).

    PubMed

    Britt, Thomas W; Jennings, Kristen S; Cheung, Janelle H; Pury, Cynthia L S; Zinzow, Heidi M

    2015-12-01

    Reports an error in "The role of different stigma perceptions in treatment seeking and dropout among active duty military personnel" by Thomas W. Britt, Kristen S. Jennings, Janelle H. Cheung, Cynthia L. S. Pury and Heidi M. Zinzow (Psychiatric Rehabilitation Journal, 2015[Jun], Vol 38[2], 142-149). Six participants were included in the sample for the treatment-seeking analyses who scored 50 or above on the PTSD Checklist, but did not meet the specific criteria on the three PTSD subscales. Of these six participants, four screened positive for another problem. Removing the two participants who did not screen positive for another problem did not affect the significance of any of the predictors in the analyses. (The following abstract of the original article appeared in record 2015-12033-001.) Many military personnel with mental health problems do not seek treatment from mental health professionals, and if they do seek treatment, they drop out of treatment before receiving the recommended number of sessions. The present study examined the role of 4 different stigma perceptions on these outcomes: perceived stigma to career, perceived stigma of differential treatment, self-stigma from seeking treatment, and stigmatizing perceptions of soldiers who seek treatment. One thousand three hundred twenty-four active duty soldiers completed a self-report survey assessment that included measures of the 4 different stigma perceptions, indices of mental health symptoms, receipt of mental health treatment, and whether they had dropped out of treatment before it was completed. Participants screening positive for a mental health problem reported higher scores on all 4 stigma perceptions. All 4 stigma perceptions were each associated with a reduced likelihood of treatment seeking when considered individually, but only stigmatizing beliefs about those who seek treatment were uniquely associated with treatment seeking. Perceived stigma for one's career and differential treatment from

  6. User Participation in Coproduction of Health Innovation: Proposal for a Synergy Project.

    PubMed

    Nygren, Jens; Zukauskaite, Elena; Westberg, Niklas

    2018-05-09

    coproduction, but different regarding, for example, context and target groups. At the synergy level, the framework methodology will be used to handle and analyze the vast amount of information generated within the subprojects. The project period is from July 1, 2018 to June 30, 2022. By addressing the objective of this project, we will create new knowledge on how to manage challenges to health innovation associated with the coproduction process, the positioning of solutions, and realization. ©Jens Nygren, Elena Zukauskaite, Niklas Westberg. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 09.05.2018.

  7. Reconstruction of the coastal morphodynamics of the Fulong-beach dune field in north-eastern Taiwan

    NASA Astrophysics Data System (ADS)

    Dörschner, Nina; Böse, Margot; Frechen, Manfred

    2010-05-01

    . References: LIN, J.C., PETLEY, D., JEN, C.-H. & HSU, M.-L. (2006): Slope movement in a dynamic environment - A case study of Tachia River, Central Taiwan. In: Quaternary International 147, p. 103-112. MURRAY, A.S., OLLEY, J.M. & CAITCHEON, G.G. (1995): Measurement of equivalent doses in quartz from contemporary water-lain sediments using optically stimulated luminescence. In: Quaternary Science Reviews 14, p. 365-371.

  8. High Resolution Infrared Heterodyne Spectroscopy: Ethylene bands at 10.5 MU m.

    NASA Astrophysics Data System (ADS)

    Morozhenko, V.; Kostiuk, T.; Buhl, D.; Hewagama, T.; Livengood, T. A.; Kollyukh, A.

    1998-09-01

    an NAS/NRC Resident Research Associateship. References: [1] Kostiuk, T., Infrared Phys.Technol. 35, 243, (1994). [2] Goldstein, J. J., M. J. Mumma, T. Kostiuk, D. Deming, F. Espenak, and D. Zipoy, \\ Icarus, 94, 45-63, (1991). [3] Kostiuk, T., R.Romani, F.Espenak, T.Livengood, J.J.Goldstein, J.of Geophys. Research, 98, 18823 (1993). [4] Hillman, J.J., D.C.Reuter, J.M.Sirota, W.E.Blass, S.J.Daunt, L.R.Senesac, A.C.Ewing, L.W. Jennings, M.C.Weber, J.S.Hager, S.L.Mahan, A.Fayt, Laboratory Space Science Workshop, Boston, April 01-03 (1998).

  9. Improving Neuromuscular Monitoring and Reducing Residual Neuromuscular Blockade With E-Learning: Protocol for the Multicenter Interrupted Time Series INVERT Study.

    PubMed

    Thomsen, Jakob Louis Demant; Mathiesen, Ole; Hägi-Pedersen, Daniel; Skovgaard, Lene Theil; Østergaard, Doris; Engbaek, Jens; Gätke, Mona Ring

    2017-10-06

    -learning module was implemented in 6 anesthesia departments on 21 November 2016. Currently, we are collecting postintervention data. The final dataset will include data from more than 10,000 anesthesia procedures. We expect to publish the results in late 2017 or early 2018. With a dataset consisting of thousands of general anesthesia procedures, the INVERT study will assess whether an e-learning module can increase anesthetists' use of neuromuscular monitoring. Clinicaltrials.gov NCT02925143; https://clinicaltrials.gov/ct2/show/NCT02925143 (Archived by WebCite® at http://www.webcitation.org/6s50iTV2x). ©Jakob Louis Demant Thomsen, Ole Mathiesen, Daniel Hägi-Pedersen, Lene Theil Skovgaard, Doris Østergaard, Jens Engbaek, Mona Ring Gätke. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 06.10.2017.

  10. The San Andreas Fault System, California

    USGS Publications Warehouse

    Wallace, Robert E.

    1990-01-01

    Maps of northern and southern California printed on flyleaf inside front cover and on adjacent pages show faults that have had displacement within the past 2 million years. Those that have had displacement within historical time are shown in red. Bands of red tint emphasize zones of historical displacement; bands of orange tint emphasize major faults that have had Quaternary displacement before historical time. Faults are dashed where uncertain, dotted where covered by sedimentary deposits, and queried when doubtful. Arrows indicate direction of relative movement; sawteeth on upper plate of thrust fault. These maps are reproductions, in major part, of selected plates from the "Fault Map of California," published in 1975 by the California Division of Mines and Geology at a scale of 1:750,000; the State map was compiled and data interpreted by Charles W. Jennings. New data about faults, not shown on the 1975 edition, required modest revisions, primarily additions however, most of the map was left unchanged because the California Division of Mines and Geology is currently engaged in a major revision and update of the 1975 edition. Because of the reduced scale here, names of faults and places were redrafted or omitted. Faults added to the reduced map are not as precise as on the original State map, and the editor of this volume selected certain faults and omitted others. Principal regions for which new information was added are the region north of the San Francisco Bay area and the offshore regions.Many people have contributed to the present map, but the editor is solely responsible for any errors and omissions. Among those contributing informally, but extensively, and the regions to which each contributed were G.A. Carver, onland region north of lat 40°N.; S.H. Clarke, offshore region north of Cape Mendocino; R.J. McLaughlin, onland region between lat 40°00' and 40°30' N. and long 123°30' and 124°30' W.; D.S. McCulloch offshore region between lat 35° and 40° N

  11. Artificial Intelligence Learning Semantics via External Resources for Classifying Diagnosis Codes in Discharge Notes.

    PubMed

    Lin, Chin; Hsu, Chia-Jung; Lou, Yu-Sheng; Yeh, Shih-Jen; Lee, Chia-Cheng; Su, Sui-Lung; Chen, Hsiang-Cheng

    2017-11-06

    extracted enough concepts to predict the diagnosis codes. Word embedding combined with a CNN showed outstanding performance compared with traditional methods, needing very little data preprocessing. This shows that future studies will not be limited by incomplete dictionaries. A large amount of unstructured information from free-text medical writing will be extracted by automated approaches in the future, and we believe that the health care field is about to enter the age of big data. ©Chin Lin, Chia-Jung Hsu, Yu-Sheng Lou, Shih-Jen Yeh, Chia-Cheng Lee, Sui-Lung Su, Hsiang-Cheng Chen. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 06.11.2017.

  12. Short- and medium-term response to storms on three Mediterranean coarse-grained beaches

    NASA Astrophysics Data System (ADS)

    Grottoli, Edoardo; Bertoni, Duccio; Ciavola, Paolo

    2017-10-01

    variations after the storm on mixed sand and gravel beaches do not necessarily mean a slower recovery of surface topography and shoreline position. Considering that all the three beaches were recently nourished with gravel, it emerged that the differences between the nourishment and the native material, in terms of size and composition, seem to have an important influence on the dynamics of the sediment stock. Considering that recent studies have remarked the high abrasion rate of gravel, further understanding of the evolution of nourishment material with time is needed. The peculiar behaviour of gravel material artificially added to an originally sandy beach suggests the need to modify the widely used classification of Jennings and Shulmeister (2002) adding a fourth additional beach typology, which could represent human-altered beaches.

  13. Validation of a single-platform method for hematopoietic CD34+ stem cells enumeration according to accreditation procedure.

    PubMed

    Massin, Frédéric; Huili, Cai; Decot, Véronique; Stoltz, Jean-François; Bensoussan, Danièle; Latger-Cannard, Véronique

    2015-01-01

    Stem cells for autologous and allogenic transplantation are obtained from several sources including bone marrow, peripheral blood or cord blood. Accurate enumeration of viable CD34+ hematopoietic stem cells (HSC) is routinely used in clinical settings, especially to monitor progenitor cell mobilization and apheresis. The number of viable CD34+ HSC has also been shown to be the most critical factor in haematopoietic engraftment. The International Society for Cellular Therapy actually recommends the use of single-platform flow cytometry system using 7-AAD as a viability dye. In a way to move routine analysis from a BD FACSCaliburTM instrument to a BD FACSCantoTM II, according to ISO 15189 standard guidelines, we define laboratory performance data of the BDTM Stem Cell Enumeration (SCE) kit on a CE-IVD system including a BD FACSCanto II flow cytometer and the BD FACSCantoTM Clinical Software. InterQCTM software, a real time internet laboratory QC management system developed by VitroTM and distributed by Becton DickinsonTM, was also tested to monitor daily QC data, to define the internal laboratory statistics and to compare them to external laboratories. Precision was evaluated with BDTM Stem Cell Control (high and low) results and the InterQC software, an internet laboratory QC management system by Vitro. This last one drew Levey-Jennings curves and generated numeral statistical parameters allowing detection of potential changes in the system performances as well as interlaboratory comparisons. Repeatability, linearity and lower limits of detection were obtained with routine samples from different origins. Agreement evaluation between BD FACSCanto II system versus BD FACSCalibur system was tested on fresh peripheral blood, freeze-thawed apheresis, fresh bone marrow and fresh cord blood samples. Instrument's measure and staining repeatability clearly evidenced acceptable variability on the different samples tested. Intra- and inter-laboratory CV in CD34+ cell absolute

  14. Rare Diseases on the Internet: An Assessment of the Quality of Online Information.

    PubMed

    Pauer, Frédéric; Litzkendorf, Svenja; Göbel, Jens; Storf, Holger; Zeidler, Jan; Graf von der Schulenburg, Johann-Matthias

    2017-01-18

    ), medical institution (P=.009), and other associations and sponsoring bodies (P=.001) as well. Overall, the quality of information on the Internet about rare diseases is low. Quality certificates are rarely used and important quality criteria are often not fulfilled completely. Additionally, some information categories are underrepresented (eg, information about psychosocial counseling, social-legal advice, and family planning). Nevertheless, due to the high amount of information provided by support groups, this study shows that these are extremely valuable sources of information for patients suffering from a rare disease and their relatives. ©Frédéric Pauer, Svenja Litzkendorf, Jens Göbel, Holger Storf, Jan Zeidler, Johann-Matthias Graf von der Schulenburg. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 18.01.2017.

  15. EMSO: European Multidisciplinary Seafloor Observatory

    NASA Astrophysics Data System (ADS)

    Favali, Paolo

    2010-05-01

    Waldmann); IMI-Irish Marine Institute (Ireland, ref. Michael Gillooly); UTM-CSIC-Unidad de Tecnologia Marina - Consejo Superior de Investigaciones Cientificas (Spain, ref. Juan Jose Danobeitia); UGOT-Goteborgs Universitet (Sweden, ref. Per Hall); HCMR-Hellenic Centre for Marine Research (Greece, ref. Vasilios Likousis); NOCS-National Oceanography Centre Southampton (United Kingdom, ref. Henry A. Ruhl); UiT-University of Tromsø (Norway, ref. Jürgen Mienert); FCT-Fundação para a Ciência e a Tecnologia (Portugal, ref. Jorge Miguel Alberto de Miranda); ITU-Istanbul Teknik Universitesi (Turkey, ref. Namik Çagatay); NIOZ-Stichting Koninklijk Nederlands Instituut voor Onderzoek der Zee (The Netherlands, ref. Jens Greinert).

  16. Seismic stratigraphic architecture of the Disko Bay trough-mouth fan system, West Greenland

    NASA Astrophysics Data System (ADS)

    Hofmann, Julia C.; Knutz, Paul C.

    2015-04-01

    succession has been divided into five seismic units, each representing different stages in the progradational accumulation of the TMF system. This poster and ongoing study will discuss how the ice-stream flow switching is linked to changes in depocentres of sedimentary sequences and further investigate the major controls, e.g. ice-sheet dynamics, ocean-climate changes, tectonic forcing and subglacial geology, that determined the evolution of the Disko Bay TMF. Essencial bibliography Mitchum, R.M. Jr., Vail, P.R., Sangree, J.B., 1977. Seismic stratigraphy and global changes of sea level, Part 6: Stratigraphic interpretation of seismic reflection patterns in depositional sequences. AAPG Memoir 26, 117-133. Ó Cofaigh, C., Andrews, J.T., Jennings, A.E., Dowdeswell, J.A., Hogan, K.A., Kilfeather, A.A., Sheldon, C., 2013. Glacimarine lithofacies, provenance and depositional processes on a West Greenland trough-mouth fan. Journal of Quaternary Science, 28(1), 13-26.

  17. Combined terrestrial and marine biomarker records from an Icelandic fjord: insights into Holocene climate drivers and marine/ terrestrial responses

    NASA Astrophysics Data System (ADS)

    Moossen, H. M.; Seki, O.; Quillmann, U.; Andrews, J. T.; Bendle, J. A.

    2012-12-01

    Holocene, while air temperatures were influenced by high solar insolation. The central Holocene climate is mainly driven by decreasing northern hemisphere insolation, while the lateral transport of energy from the equator into the North Atlantic region drives climate change in the late Holocene. D'Andrea, W.J., Huang, Y., Fritz, S.C., Anderson, N.J., (2011) Abrupt Holocene climate change as an important factor for human migration in West Greenland. Proceedings of the National Academy of Sciences of the United States of America, 108(24), 9765-9769. Hurrell, J.W., (1995) Decadal trends in the North Atlantic Oscillation - Regional temperatures and precipitation. Science, 269(5224), 676-679. Quillmann, U., Jennings, A., Andrews, J., (2010) Reconstructing Holocene palaeoclimate and palaeoceanography in Isafjaroardjup, northwest Iceland, from two fjord records overprinted by relative sea-level and local hydrographic changes. Journal of Quaternary Science, 25(7), 1144-1159.

  18. Conceptualization and Implementation of the Central Information Portal on Rare Diseases: Protocol for a Qualitative Study.

    PubMed

    Litzkendorf, Svenja; Hartz, Tobias; Göbel, Jens; Storf, Holger; Pauer, Frédéric; Babac, Ana; Lührs, Verena; Bruckner-Tuderman, Leena; Schauer, Franziska; Schmidtke, Jörg; Biehl, Lisa; Wagner, Tof; Graf von der Schulenburg, J-Matthias; Frank, Martin

    2018-05-11

    privacy, enabling links with high-quality information. Moreover, 19 users tested all the developed routines based on usability and comprehensibility. Subsequently, we improved the visual presentation of search results and other important search functions. The implemented information portal, ZIPSE, provides high-quality information on rare diseases from a central point of access. By integrating the targeted groups as well as different experts on medical information during the construction, the website can assure an improved search for information for users. ZIPSE can also serve as a model for other Web-based information systems in the field of rare diseases. RR1-10.2196/7425. ©Svenja Litzkendorf, Tobias Hartz, Jens Göbel, Holger Storf, Frédéric Pauer, Ana Babac, Verena Lührs, Leena Bruckner-Tuderman, Franziska Schauer, Jörg Schmidtke, Lisa Biehl, TOF Wagner, J-Matthias Graf von der Schulenburg, Martin Frank. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 11.05.2018.

  19. Water vapor in Titan's atmosphere observed by Cassini/CIRS data

    NASA Astrophysics Data System (ADS)

    Cottini, V.; Nixon, C. A.; Jennings, D. E.; Teanby, N. A.; Anderson, C. M.; Irwin, P. G.; Flasar, F. M.

    2011-12-01

    altitude.These results will be compared to existing photochemical models of Titan's oxygen species, and we will conclude with a discussion of future plans by the CIRS team for improving knowledge of the water abundance in Titan's atmosphere. References [3] Cottini, V., Nixon, C.A., Jennings, D.E., de Kok, R., Teanby, N.A., Irwin, P.G.J. and Flasar F.M., 2011. Spatial and temporal variations in Titan's surface temperatures from Cassini CIRS observations. Planetary and Space Science, doi:10.1016/j.pss.2011.03.015 [1] Coustenis, A., and 8 colleagues, 1998. Evidence for water vapor in Titan's atmosphere from ISO/SWS data. Astronomy and Astrophysics, v.336, p.L85-L89 [2] Flasar, F. M., and 44 colleagues, 2004. Exploring the Saturn system in the thermal infrared: The Composite Infrared Spectrometer. Space Sci. Rev. 115, 169 - 297

  20. Leslie Peltier, Amateur Astronomer and Observer Extraordinaire

    NASA Astrophysics Data System (ADS)

    Corbin, B. G.

    2003-12-01

    Leslie Copus Peltier, (Jan. 2, 1900-May 10, 1980) was called "the world's greatest non-professional astronomer" by none other than Harlow Shapley, and also referred to as the "the world's greatest living amateur astronomer". He began observing variable stars on March 1, 1918 with an observation of R. Leonis and at the time of his death had made a total of 132,123 observations of variable stars. These were reported to the AAVSO on a consecutive monthly basis stretching from 1918 to his death in 1980. As of October 2003, he was still on AAVSO's list of the top 25 observers in its history. Born on a farm near Delphos, Ohio, his parents were well read and their home was filled with books on different subjects, including nature guides. As a young man he studied the flora and fauna of the area and in 1915 began his study of the heavens with Vega being the first star he identified. After the purchase of a 2-inch spyglass, his observations of variable stars began to be noticed by professional astronomers and the AAVSO loaned him a 4-inch Mogey refractor; shortly thereafter Henry Norris Russell of Princeton loaned him via the AAVSO a 6-inch refractor, a comet seeker of short focus. He discovered 12 comets, 10 of which carry his name, and 6 novae or recurring novae. His design of the "Merry-Go-Round Observatory" was a novel approach with the whole observatory revolving around the observer while seated in his observing chair. Miami University (Ohio) later donated to him their 12-inch Clark refractor with its dome. His first book, Starlight Nights: The Adventures of a Star-Gazer, appeared in 1965. This autobiography, an ode to the joys of observing both the night sky and nature, was written in beautifully descriptive language that helped lead countless readers into astronomy. Departing from astronomy, in 1977 he published The Place on Jennings Creek. Written in the style of the 19th century naturalist, the book was devoted to his family's home, Brookhaven, and its natural

  1. Applying STOPP Guidelines in Primary Care Through Electronic Medical Record Decision Support: Randomized Control Trial Highlighting the Importance of Data Quality.

    PubMed

    Price, Morgan; Davies, Iryna; Rusk, Raymond; Lesperance, Mary; Weber, Jens

    2017-06-15

    prescribing workflows. Many of the STOPP criteria can be implemented in EMRs using simple logic. However, data quality in EMRs continues to be a challenge and was a limiting step in the effectiveness of the decision support in this study. This is important as decision makers continue to fund implementation and adoption of EMRs with the expectation of the use of advanced tools (such as decision support) without ongoing review of data quality and improvement. Clinicaltrials.gov NCT02130895; https://clinicaltrials.gov/ct2/show/NCT02130895 (Archived by WebCite at http://www.webcitation.org/6qyFigSYT). ©Morgan Price, Iryna Davies, Raymond Rusk, Mary Lesperance, Jens Weber. Originally published in JMIR Medical Informatics (http://medinform.jmir.org), 15.06.2017.

  2. PREFACE: The Science of Making Torque from Wind 2014 (TORQUE 2014)

    NASA Astrophysics Data System (ADS)

    Mann, Jakob; Bak, Christian; Bechmann, Andreas; Bingöl, Ferhat; Dellwik, Ebba; Dimitrov, Nikolay; Giebel, Gregor; Hansen, Martin O. L.; Jensen, Dorte Juul; Larsen, Gunner; Aagaard Madsen, Helge; Natarajan, Anand; Rathmann, Ole; Sathe, Ameya; Nørkær Sørensen, Jens; Nørkær Sørensen, Niels

    2014-06-01

    O L Hansen, Dorte Juul Jensen, Gunner Larsen, Helge Aagaard Madsen, Jakob Mann, Anand Natarajan, Ole Rathmann, Ameya Sathe, Jens Nørkær Sørensen and Niels Nørkær Sørensen, who are all co-editors of these proceedings. The resources provided by the Center for Computational Wind Turbine Aerodynamics and Atmospheric Turbulence funded by the Danish Council for Strategic Research grant no. 09-067216 and the Danish Ministry of Science, Innovation and Higher Education Technology and Production, grant no. 11- 117018 are gratefully acknowledged. We are also immensely indebted to the very responsive help and support from the editorial team at IoP, especially Sarah Toms and Anete Ashton, during the reviewing process of these proceedings. We are looking forward to meeting you in Copenhagen and also to Torque 2016, which will take place at the Technical University of Munich, Germany. Roskilde, Denmark, June 2014 Ebba Dellwik, Ameya Sathe and Jakob Mann Technical University of Denmark EAWE DTU

  3. A MATLAB based Distributed Real-time Simulation of Lander-Orbiter-Earth Communication for Lunar Missions

    NASA Astrophysics Data System (ADS)

    Choudhury, Diptyajit; Angeloski, Aleksandar; Ziah, Haseeb; Buchholz, Hilmar; Landsman, Andre; Gupta, Amitava; Mitra, Tiyasa

    communication. The DRTS setup thus developed serves as an important and inexpensive test bench for trying out remote controlled applications on the rover, for example, from an earth station. The simulation is modular and the system is composable. Each of the processes can be aug-mented with relevant simulation modules that handle the events to simulate specific function-alities. With stringent energy saving requirements on most rovers, such a simulation set up, for example, can be used to design optimal rover movement control strategies from the orbiter in conjunction with autonomous systems on the rover itself. References 1. Lunar and Planetary Department, Moscow University, Lunokhod 1, "http://selena.sai.msu.ru/Home/Spa 2. NASA History Office, Guidelines for Advanced Manned Space Vehicle Program, "http://history.nasa.gov 35ann/AMSVPguidelines/top.htm" 3. Consultative Committee For Space Data Systems, "Proximity-1 Space Link Protocol" CCSDS 211.0-B-1 Blue Book. October 2002. 4. Segui, J. and Jennings, E., "Delay Tolerant Networking-Bundle Protocol Simulation", in Proceedings of the 2nd IEEE International Conference on Space Mission Challenges for Infor-mation Technology, 2006.

  4. What to Build for Middle-Agers to Come? Attractive and Necessary Functions of Exercise-Promotion Mobile Phone Apps: A Cross-Sectional Study.

    PubMed

    Liao, Gen-Yih; Chien, Yu-Tai; Chen, Yu-Jen; Hsiung, Hsiao-Fang; Chen, Hsiao-Jung; Hsieh, Meng-Hua; Wu, Wen-Jie

    2017-05-25

    with 14 design features, medium level with 6 features, whereas low-level participants are recommended with 1 feature. The analysis suggests that the implementation of demanded features could be low, as the average prevalence of demanded design features is 20% (4.3/21). Surprisingly, social comparison and social support, most implemented features in current apps, were categorized into the indifferent category. The magnitude of effect is larger for MPSE because it effects quality perception of more design features than PA. Delving into the 52 regression models revealed that high MPSE more likely induces attractive or one- dimensional categorization, suggesting the importance of technological self-efficacy on eHealth care promotion. This study is the first to propose middle-agers' needs in relation to mobile phone exercise-promotion. In addition to the tailor-made recommendations, suggestions are offered to app designers to enhance the performance of persuasive features. An interesting finding on change of quality perception attributed to MPSE is proposed as future research. ©Gen-Yih Liao, Yu-Tai Chien, Yu-Jen Chen, Hsiao-Fang Hsiung, Hsiao-Jung Chen, Meng-Hua Hsieh, Wen-Jie Wu. Originally published in JMIR Mhealth and Uhealth (http://mhealth.jmir.org), 25.05.2017.

  5. A comparison of modifications of the McMaster method for the enumeration of Ascaris suum eggs in pig faecal samples.

    PubMed

    Pereckiene, A; Kaziūnaite, V; Vysniauskas, A; Petkevicius, S; Malakauskas, A; Sarkūnas, M; Taylor, M A

    2007-10-21

    The comparative efficacies of seven published McMaster method modifications for faecal egg counting were evaluated on pig faecal samples containing Ascaris suum eggs. Comparisons were made as to the number of samples found to be positive by each of the methods, the total egg counts per gram (EPG) of faeces, the variations in EPG obtained in the samples examined, and the ease of use of each of the methods. Each method was evaluated after the examination of 30 samples of faeces. The positive samples were identified by counting A. suum eggs in one, two and three sections of newly designed McMaster chamber. In the present study compared methods were reported by: I-Henriksen and Aagaard [Henriksen, S.A., Aagaard, K.A., 1976. A simple flotation and McMaster method. Nord. Vet. Med. 28, 392-397]; II-Kassai [Kassai, T., 1999. Veterinary Helminthology. Butterworth-Heinemann, Oxford, 260 pp.]; III and IV-Urquhart et al. [Urquhart, G.M., Armour, J., Duncan, J.L., Dunn, A.M., Jennings, F.W., 1996. Veterinary Parasitology, 2nd ed. Blackwell Science Ltd., Oxford, UK, 307 pp.] (centrifugation and non-centrifugation methods); V and VI-Grønvold [Grønvold, J., 1991. Laboratory diagnoses of helminths common routine methods used in Denmark. In: Nansen, P., Grønvold, J., Bjørn, H. (Eds.), Seminars on Parasitic Problems in Farm Animals Related to Fodder Production and Management. The Estonian Academy of Sciences, Tartu, Estonia, pp. 47-48] (salt solution, and salt and glucose solution); VII-Thienpont et al. [Thienpont, D., Rochette, F., Vanparijs, O.F.J., 1986. Diagnosing Helminthiasis by Coprological Examination. Coprological Examination, 2nd ed. Janssen Research Foundation, Beerse, Belgium, 205 pp.]. The number of positive samples by examining single section ranged from 98.9% (method I), to 51.1% (method VII). Only with methods I and II, there was a 100% positivity in two out of three of the chambers examined, and FEC obtained using these methods were significantly (p<0.01) higher

  6. EDITORIAL: Focus on Quantum Control

    NASA Astrophysics Data System (ADS)

    Rabitz, Herschel

    2009-10-01

    Control of quantum phenomena has grown from a dream to a burgeoning field encompassing wide-ranging experimental and theoretical activities. Theoretical research in this area primarily concerns identification of the principles for controlling quantum phenomena, the exploration of new experimental applications and the development of associated operational algorithms to guide such experiments. Recent experiments with adaptive feedback control span many applications including selective excitation, wave packet engineering and control in the presence of complex environments. Practical procedures are also being developed to execute real-time feedback control considering the resultant back action on the quantum system. This focus issue includes papers covering many of the latest advances in the field. Focus on Quantum Control Contents Control of quantum phenomena: past, present and future Constantin Brif, Raj Chakrabarti and Herschel Rabitz Biologically inspired molecular machines driven by light. Optimal control of a unidirectional rotor Guillermo Pérez-Hernández, Adam Pelzer, Leticia González and Tamar Seideman Simulating quantum search algorithm using vibronic states of I2 manipulated by optimally designed gate pulses Yukiyoshi Ohtsuki Efficient coherent control by sequences of pulses of finite duration Götz S Uhrig and Stefano Pasini Control by decoherence: weak field control of an excited state objective Gil Katz, Mark A Ratner and Ronnie Kosloff Multi-qubit compensation sequences Y Tomita, J T Merrill and K R Brown Environment-invariant measure of distance between evolutions of an open quantum system Matthew D Grace, Jason Dominy, Robert L Kosut, Constantin Brif and Herschel Rabitz Simplified quantum process tomography M P A Branderhorst, J Nunn, I A Walmsley and R L Kosut Achieving 'perfect' molecular discrimination via coherent control and stimulated emission Stephen D Clow, Uvo C Holscher and Thomas C Weinacht A convenient method to simulate and visually

  7. Mobile Technology in E-Learning for Undergraduate Medical Education on Emergent Otorhinolaryngology-Head and Neck Surgery Disorders: Pilot Randomized Controlled Trial.

    PubMed

    Lee, Li-Ang; Wang, Shu-Ling; Chao, Yi-Ping; Tsai, Ming-Shao; Hsin, Li-Jen; Kang, Chung-Jan; Fu, Chia-Hsiang; Chao, Wei-Chieh; Huang, Chung-Guei; Li, Hsueh-Yu; Chuang, Cheng-Keng

    2018-03-08

    significantly higher scores of satisfaction (difference 2, 95% CI 2-4; P=.01), pragmatic quality (difference 1.7, 95% CI 0.1-2.7; P=.03), and hedonic stimulation (difference 1.9, 95% CI 0.3-3.1; P=.01) compared with the PPS group. Qualitative feedback indicated that the various games in the IM module attracted the participants' attention but that the nonlinearly arranged materials affected their learning. Using M-TEL for undergraduate medical education on emergent ORL-HNS disorders, an IM module seems to be useful for gaining knowledge, but competency may need to occur elsewhere. While the small sample size reduces the statistical power of our results, its design seems to be appropriate to determine the effects of M-TEL using a larger group. ClinicalTrials.gov NCT02971735; https://clinicaltrials.gov/ct2/show/NCT02971735 (Archived by WebCite at http://www.webcitation.org/6waoOpCEV). ©Li-Ang Lee, Shu-Ling Wang, Yi-Ping Chao, Ming-Shao Tsai, Li-Jen Hsin, Chung-Jan Kang, Chia-Hsiang Fu, Wei-Chieh Chao, Chung-Guei Huang, Hsueh-Yu Li, Cheng-Keng Chuang. Originally published in JMIR Medical Education (http://mededu.jmir.org), 08.03.2018.

  8. Development of an Agent-Based Model to Investigate the Impact of HIV Self-Testing Programs on Men Who Have Sex With Men in Atlanta and Seattle.

    PubMed

    Luo, Wei; Katz, David A; Hamilton, Deven T; McKenney, Jennie; Jenness, Samuel M; Goodreau, Steven M; Stekler, Joanne D; Rosenberg, Eli S; Sullivan, Patrick S; Cassels, Susan

    2018-06-29

    % in Atlanta and Seattle, respectively. Previous studies provided sufficient data to estimate the model parameters representing nuanced HIV testing patterns and HIV self-test distribution. We calibrated the models to simulate the epidemics representing Atlanta and Seattle, including matching the expected stable HIV prevalence. The revised model facilitated the estimation of changes in 10-year HIV incidence based on counterfactual scenarios of HIV self-test distribution strategies and their impact on testing behaviors. We demonstrated that the extension of an existing agent-based HIV transmission model was sufficient to simulate the HIV epidemics among MSM in Atlanta and Seattle, to accommodate a more nuanced depiction of HIV testing behaviors than previous models, and to serve as a platform to investigate how HIV self-tests might impact testing and HIV transmission patterns among MSM in Atlanta and Seattle. In our future studies, we will use the model to test how different HIV self-test distribution strategies might affect HIV incidence among MSM. ©Wei Luo, David A Katz, Deven T Hamilton, Jennie McKenney, Samuel M Jenness, Steven M Goodreau, Joanne D Stekler, Eli S Rosenberg, Patrick S Sullivan, Susan Cassels. Originally published in JMIR Public Health and Surveillance (http://publichealth.jmir.org), 29.06.2018.

  9. Internet-Delivered Cognitive Behavioral Therapy for Children With Pain-Related Functional Gastrointestinal Disorders: Feasibility Study.

    PubMed

    Lalouni, Maria; Ljótsson, Brjánn; Bonnert, Marianne; Hedman-Lagerlöf, Erik; Högström, Jens; Serlachius, Eva; Olén, Ola

    2017-08-10

    parent reported that the symptoms had worsened. We observed a large within-group effect size on the primary outcome measure, child-rated gastrointestinal symptoms from pretreatment to posttreatment (Cohen d=1.14, P<.001, 95% CI 0.69-1.61), and this effect size was maintained at 6-month follow-up (Cohen d=1.40, P<.001, 95% CI 1.04-1.81). We also observed significant improvements from pretreatment to posttreatment on a wide range of child- and parent-rated measures including quality of life, pain intensity, anxiety, depression, and school absence. All results remained stable or were further improved at 6-month follow-up. This study shows that children with longstanding P-FGIDs, and their parents, perceive exposure-based Internet-CBT as a helpful and feasible treatment. The included children improved significantly despite a long duration of abdominal symptoms before the intervention. The treatment shows potential to be highly effective for P-FGIDs. The results need to be confirmed in a randomized controlled trial (RCT). ©Maria Lalouni, Brjánn Ljótsson, Marianne Bonnert, Erik Hedman-Lagerlöf, Jens Högström, Eva Serlachius, Ola Olén. Originally published in JMIR Mental Health (http://mental.jmir.org), 10.08.2017.

  10. PREFACE: Wake Conference 2015

    NASA Astrophysics Data System (ADS)

    Barney, Andrew; Nørkær Sørensen, Jens; Ivanell, Stefan

    2015-06-01

    at scientists and PhD students working in the field of wake dynamics. The conference covers the following subject areas: Wake and vortex dynamics, instabilities in trailing vortices and wakes, simulation and measurements of wakes, analytical approaches for modeling wakes, wake interaction and other wind farm investigations. Many people have been involved in producing the 2015 Wake Conference proceedings. The work by the more than 60 reviewers ensuring the quality of the papers is greatly appreciated. The timely evaluation and coordination of the reviews would not have been possible without the work of the section editors: Christian Masson, ÉTS, Fernando Porté-Agel, EPFL, Gerard Schepers, ECN Wind Energy, Gijs Van Kuik, Delft University, Gunner Larsen, DTU Wind Energy, Jakob Mann, DTU Wind Energy, Javier Sanz Rodrigo, CENER, Johan Meyers, KU Leuven, Rebecca Barthelmie, Cornell University, Sandrine Aubrun-Sanches, Université d'Orléans and Thomas Leweke, IRPHE-CNRS. We are also immensely indebted to the very responsive support from the editorial team at IOP Publishing, especially Sarah Toms, during the review process of these proceedings. Visby, Sweden, June 2015 Andrew Barney, Jens Nørkær Sørensen and Stefan Ivanell Uppsala University - Campus Gotland

  11. Assessing the Efficacy of an App-Based Method of Family Planning: The Dot Study Protocol.

    PubMed

    Simmons, Rebecca G; Shattuck, Dominick C; Jennings, Victoria H

    2017-01-18

    assess pregnancy status over time. This paper outlines the protocol for this efficacy trial, following the Standard Protocol Items: Recommendations for Intervention Trials checklist, to provide an overview of the rationale, methodology, and analysis plan. Participants will be asked to provide daily sexual history data and periodically answer surveys administered through a call center or directly on their phone. Funding for the study was provided in 2013 under the United States Agency for International Development Fertility Awareness for Community Transformation project. Recruitment for the study will begin in January of 2017. The study is expected to last approximately 18 months, depending on recruitment. Findings on the study's primary outcomes are expected to be finalized by September 2018. Reproducibility and transparency, important aspects of all research, are particularly critical in developing new approaches to research design. This protocol outlines the first study to prospectively test both the efficacy (correct use) and effectiveness (actual use) of a pregnancy prevention app. This protocol and the processes it describes reflect the dynamic integration of mobile technologies, a call center, and Health Insurance Portability and Accountability Act-compliant study procedures. Future fertility app studies can build on our approaches to develop methodologies that can contribute to the evidence base around app-based methods of contraception. ClinicalTrials.gov NCT02833922; https://clinicaltrials.gov/ct2/show/NCT02833922 (Archived be WebCite at http://www.webcitation.org/6nDkr0e76). ©Rebecca G Simmons, Dominick C Shattuck, Victoria H Jennings. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 18.01.2017.

  12. [Reasons for the construction of Bispebjerg Hospital--a hospital with light, air and freedom of nature].

    PubMed

    Permin, Henrik; Wagner, Peter

    2009-01-01

    Since the 1850ies the city of Copenhagen changed, ramparts were removed or remodelled as parks, industries were established. The new factories and wharfs expanded, labourers were needed; many country people moved into the city to find work and thus the population increased immensely. In Copenhagen a few hospitals only were present around 1850; The Royal Frederik Hospital (now the Museum of applied Arts) was the only hospital in the modern sense of the word. Other institutions with "hospital" as part of their name as e.g. General Hospital (Almindelig Hospital) or Ladegaarden were a mixture of hospital and workhouse and The Royal Maternity Hospital founded in 1750. The wealthy and the upper middle class citizens were nursed or cured at home. At the end of the nineteenth century medical doctors could successfully cure some diseases, and surgeons could after the introduction of the anesthetic and aseptic treatment carry out operations with diminished risks of complications. Copenhagen's first modern hospital, Municipal Hospital (Kommunehospitalet) opened 1863, but in a very short time it was permanently overcrowded. Although two small hospitals Blegdam Hospital (isolation hospital) and the Oresund Hospital (quarantine station) were established a large new hospital was needed. Although the financial situation of the city of Copenhagen was strained due to the expenditures caused by the rapidly growing population within the city itself and the villages incorporated into it, the first social democratic mayor Jens Jensen wanted to secure his voters the same care and treatment as citizens of better means. As this view was accepted by the majority of the city council a hospital in the then modern and functional pavilion system (ascribed to Florence Nightingale) with buildings surrounded by gardens was planned. The architect Martin Nyrop (1849-1921) who had just completed the monumental and beautiful Copenhagen City Hall along with the engineer AC Karsten (1857-1931) and

  13. Snow Radar Derived Surface Elevations and Snow Depths Multi-Year Time Series over Greenland Sea-Ice During IceBridge Campaigns

    NASA Astrophysics Data System (ADS)

    Perkovic-Martin, D.; Johnson, M. P.; Holt, B.; Panzer, B.; Leuschen, C.

    2012-12-01

    land surveyed areas of Thule and Sondrestrom air bases. The radar measurements were compared against the ATM and the GPS measurements that were located in the estimated radar footprints, which resulted in an overall error of ~ 0.3 m between the radar and ATM. The agreement between ATM and GPS survey is within +/- 0.1 m. References: [1] http://www.nasa.gov/mission_pages/icebridge/ [2] Panzer, B. et. al, "An ultra-wideband, microwave radar for measuring snow thickness on sea ice and mapping near-surface internal layers in polar firn," Submitted to J. of Glaciology Instr. and Tech., July 23, 2012. [3] Krabill, William B. 2009 and 2011, updated current year. IceBridge ATM L1B Qfit Elevation and Return Strength. Boulder, Colorado USA: National Snow and Ice Data Center. Digital media. [4] Chih-Chung Chang and Chih-Jen Lin. "Libsvm: a library for support vector machines", ACM Transactions on Intelligent Systems and Technology, 2:2:27:1-27:27, 2011. [5] Krabill, William B. 2009 and 2011, updated current year. IceBridge CAMBOT L1B Geolocated Images, [2009-04-25, 2011-04-15]. Boulder, Colorado USA: National Snow and Ice Data Center. Digital media. [6] Dominguez, Roseanne. 2011, updated current year. IceBridge DMS L1B Geolocated and Orthorectified Images. Boulder, Colorado USA: National Snow and Ice Data Center. Digital media

  14. Use of stable carbon and nitrogen isotope ratios in size segregated aerosol particles for the O/I penetration evaluation

    NASA Astrophysics Data System (ADS)

    Garbaras, Andrius; Garbariene, Inga; Masalaite, Agne; Ceburnis, Darius; Krugly, Edvinas; Kvietkus, Kestutis; Remeikis, Vidmantas; Martuzevicius, Dainius

    2015-04-01

    particles penetrates from outside to inside. Observed isotope ratio depletion indicates that information about aerosol sources can be lost if measurements are performed only inside house. Using carbon and nitrogen isotope ratios data set, we were able to identify and distinguish main aerosol sources (traffic, heating activities) and penetration of aerosol particles from outdoor to indoor. Acknowledgment This work was supported by Research Council of Lithuania under grant "Pollution Control in Biomass Combustion: from Pollutant Formation to Human Exposure" (BioMassPoll), Project no. ATE05/2012. EPA Ireland is acknowledged for the fellowship grant of D. Ceburnis 1. Garbaras, A. Masalaite, I. Garbariene, D. Ceburnis, E. Krugly V. Remeikis, E. Puida K. Kvietkus, D. Martuzevicius, Stable carbon fractionation in size-segregated aerosol particles produced by controlled biomass burning, Journal of Aerosol Science, Vol. 79, p. 86-96 (2015); 2. D. Ceburnis, A. Garbaras, S. Szidat, M. Rinaldi, S. Fahrni, N. Perron, L. Wacker, S. Leinert, V. Remeikis, M. C. Facchini, A. S. H. Prevot, S. G. Jennings, and C. D. O'Dowd, Quantification of the carbonaceous matter origin in submicron marine aerosol particles by dual carbon isotope analysis, Atmospheric Chemistry and Physics, Vol 11, pp. 8593-8606 (2011); 3. V. Ulevicius, S. Bycenkiene, V. Remeikis, A. Garbaras, S. Kecorius, J. Andriejauskiene, D. Jasineviciene, G. Mocnik, Characterization of pollution events in the East Baltic region affected by regional biomass fire emissions, Atmospheric Research, Vol. 98 (2-4), pp. 190-200 (2010).

  15. PREFACE: The XI Mexican School on Particles and Fields

    NASA Astrophysics Data System (ADS)

    2005-01-01

    Veracruz. We acknowledge the help of our colleagues in the Organizing Committee: Norma Bagatella Flores (FFIA-U. Veracruzana), Heriberto Castilla Valdés (CINVESTAV-U. Zacatenco), Lorenzo Díz Cruz (FCFM-BUAP), Juan José Godina Nava (CINVESTAV-U. Zacatenco), Gerardo Herrera Corral (CINVESTAV-U. Zacatenco), German Mandujano Vallejo (FFIA-U. Veracruzana), Miguel Ángel Pérez Angón (CINVESTAV-U. Zacatenco), Efraín Rojas Marcial (FFIA-U. Veracruzana) and Carlos Vargas Madrazo (FFIA-U Veracruzana). Many thanks also to our Conference Secretaries Patricia Carranza and Soledad López for the efficiency with which they carried out their job and their dedication. Special thanks go to María Guadalupe Colorado Hernández and Javier Ignacio Fragoso Tizapan, whose help in carrying out the School was essential, without their collaboration this School would not have been the same. We take this opportunity to thank most warmly all the speakers for delivering excellent lectures which made this event a success. Moreover, to our utmost delight, the students participated very enthusiastically and we hope that this school will contribute considerably towards their academic development. The future of scientific endeavour always depends upon the students. Adnan Bashir (IFM-UMSNH) Jens Erler (IF-UNAM) Rául Hernández (FFIA-UV) Myriam Mondragón (IF-UNAM) Luis Villaseñor (IFM-UMSNH)

  16. PREFACE: Preface

    NASA Astrophysics Data System (ADS)

    Luo, Qingming; Wang, Lihong V.; Tuchin, Valery V.

    2011-02-01

    Qingming LuoLihong V WangValery V TuchinConference Chairs 9th International Conference on Photonics and Imaging in Biology and Medicine (PIBM 2010)2-5 November 2010Wuhan, China EditorsQingming Luo, Huazhong University of Science and Technology (China)Lihong V Wang , Washington University in St. Louis (USA)Valery V Tuchin, Saratov State University (Russia) Sponsored and Organized byHuazhong University of Science and Technology (China)Wuhan National Laboratory for Optoelectronics (China)Britton Chance Center for Biomedical Photonics (China) Technical Co-sponsored byIBOS-International Biomedical Optics SocietyThe Chinese Optical SocietyThe Biophysical Society of China Co-organized byKey Laboratory of Biomedical Photonics, Ministry of Education (China)Virtual Research Center of Biomedical Photonics, Ministry of Education (China)Hubei Bioinformatics and Molecular Imaging Key Laboratory (China) CONFERENCE COMMITTEES Honorary ChairsBritton Chance, University of Pennsylvania (USA)Bingkun Zhou, Tsinghua University (China) Conference ChairsQingming Luo, Huazhong University of Science and Technology (China)Lihong V Wang , Washington University in St. Louis (USA)Valery V Tuchin, Saratov State University (Russia) Advisory CommitteeSydney Brenner, The Salk Institute in La Jolla, California (USA)Howard Chen, K&L Gates (USA)Jing Cheng, Tsinghua University (China)Shu Chien, University of California, San Diego (USA)Paul Ching-Wu Chu, University of Houston (USA)Aaron Ciechanover, Technion-Israel Institute of Technology, Haifa (Israel)A Stephen Dahms, Alfred E Mann Foundation for Biomedical Engineering (USA)Da Hsuan Feng, National Cheng Kung University (Taiwan, China)Steven R Goodman, SUNY Upstate Medical University (USA)Barry Halliwell, National University of Singapore (Singapore)John Hart, The University of Texas at Dallas (USA)George Radda, Agency for Science, Technology and Research (A*STAR) (Singapore)Zihe Rao, Nankai University (China)Brian M Salzberg, University of Pennsylvania (USA)Ruey-Jen

  17. PREFACE: Seventh International Conference on Dissociative Recombination: Theory, Experiments and Applications

    NASA Astrophysics Data System (ADS)

    van der Zande, Wim J.

    2009-09-01

    Hamberg55. Peet Hickman 16. Daan Schram36. Oldrich Novotny56. Christiaan Jungen 17. Dahbia Talbi37. Matthias Danielson57. Jozef Varju 18. Steven Guberman38. Radek Plasil58. Juraj Glosik 19. Mats Larsson39. Richard Thomas 20. Åsa Larson40. Andreas Wolf Absent from the picture: Detlev Reiter, Brian Mitchell, Jens Hoffmann and Dave Parker

  18. The dimensionality reduction at surfaces as a playground for many-body and correlation effects

    NASA Astrophysics Data System (ADS)

    Tejeda, A.; Michel, E. G.; Mascaraque, A.

    2013-03-01

    antiferromagnetic surfaces. Ortega reports on the gap of molecular layers on metal systems, where the metal-organic interaction affects the organic gap through correlation effects. Finally, Cazalilla presents a study of the phase diagram of one-dimensional atoms or molecules displaying a Kondo-exchange interaction with the substrate. Acknowledgments The editors are grateful to all the invited contributors to this special section of Journal of Physics: Condensed Matter. We also thank the IOP Publishing staff for handling the administrative matters and the refereeing process. Correlation and many-body effects at surfaces contents The dimensionality reduction at surfaces as a playground for many-body and correlation effectsA Tejeda, E G Michel and A Mascaraque Electron-phonon coupling in quasi-free-standing grapheneJens Christian Johannsen, Søren Ulstrup, Marco Bianchi, Richard Hatch, Dandan Guan, Federico Mazzola, Liv Hornekær, Felix Fromm, Christian Raidel, Thomas Seyller and Philip Hofmann Exploring highly correlated materials via electron pair emission: the case of NiO/Ag(100)F O Schumann, L Behnke, C H Li and J Kirschner Coherent excitations and electron-phonon coupling in Ba/EuFe2As2 compounds investigated by femtosecond time- and angle-resolved photoemission spectroscopyI Avigo, R Cortés, L Rettig, S Thirupathaiah, H S Jeevan, P Gegenwart, T Wolf, M Ligges, M Wolf, J Fink and U Bovensiepen Understanding the insulating nature of alkali-metal/Si(111):B interfacesY Fagot-Revurat, C Tournier-Colletta, L Chaput, A Tejeda, L Cardenas, B Kierren, D Malterre, P Le Fèvre, F Bertran and A Taleb-Ibrahimi What about U on surfaces? Extended Hubbard models for adatom systems from first principlesPhilipp Hansmann, Loïg Vaugier, Hong Jiang and Silke Biermann Influence of on-site Coulomb interaction U on properties of MnO(001)2 × 1 and NiO(001)2 × 1 surfacesA Schrön, M Granovskij and F Bechstedt On the organic energy gap problemF Flores, E Abad, J I Martínez, B Pieczyrak and J Ortega

  19. PREFACE: The Science of Making Torque from Wind

    NASA Astrophysics Data System (ADS)

    Sørensen, Jens N.; Hansen, Martin O. L.; Hansen, Kurt S.

    2007-06-01

    conference to bring together scientists and engineers working in the fields of aerodynamics, aeroelasticity, aeroacoustics, aeroelastic control, wind conditions and wind farms. The first conference entitled `The Science of making Torque from Wind' was organized by DUWIND and held at Delft University, 19-21 April 2004. Owing to the great success of this conference where more than 60 papers were presented, we decided to follow it with a similar conference at the Technical University of Denmark (DTU) in Lyngby. It is our hope that others will take up the idea and continue this series of conferences. An explicit objective of the conference is to meet the high standards applied in several other branches of science and technology. The EAWE has the responsibility for the scientific quality of the content. All papers presented at the conference have had an abstract review as well as a full paper review by at least two reviewers. Out of the approximately 120 submitted abstracts, 86 papers were finally approved to be presented at the conference. It is expected that many of the papers will subsequently be published in scientific journals. Toward that end, the editors of Wind Energy and Journal of Solar Energy Engineering have expressed their interest in letting the most promising papers be subjected to a second review, for the purpose of having them published as journal papers. The EWEA staff is thanked for organizing the PR on the conference and the EAWE board members for valuable help in the reviewing process and for delivering session chairmen. Staff members at the Department of Mechanical Engineering at DTU and Risø were responsible for the organization. Special thanks go to DTU for providing lecture and meeting rooms, and to LM Glasfiber, Vestas Wind Systems and Siemens Wind Power for financial support. Jens Nørkær Sørensen, Conference Chairman 21 June 2007

  20. Ex vivo culture of human fetal gonads: manipulation of meiosis signalling by retinoic acid treatment disrupts testis development.

    PubMed

    Jørgensen, A; Nielsen, J E; Perlman, S; Lundvall, L; Mitchell, R T; Juul, A; Rajpert-De Meyts, E

    2015-10-01

    '-deoxyuridine (BrdU) incorporation assay. A novel ex vivo 'hanging-drop' culture model for human fetal gonads was successfully established. Continued proliferation of cells without signs of increased apoptosis was observed after 2 weeks of culture. In cultured fetal ovaries treated with RA, an increased number of meiotic germ cells (P < 0.05) and DMRT1-positive oogonia initiating meiosis (P < 0.05) was observed, which is in agreement with a previous study. In fetal testes, RA-treatment resulted in a decreased number of gonocytes (P < 0.05), a reduced percentage of proliferating gonocytes (P < 0.05), altered expression pattern of the somatic cell markers AMH and COUP-TFII, as well as disrupted seminiferous cord structure and testis morphology. The number of samples included in this study was relatively small due to the limited availability of human fetal tissue. The hanging-drop culture, similarly to other organ culture approaches, allows studies of germ cell-somatic niche interactions and determination of effects after manipulating specific signalling pathways. Our novel finding of disrupted fetal testis development after treatment with RA indicates that abnormal meiosis regulation can potentially cause gonadal dysgenesis. Further studies will elucidate the exact mechanisms and timing of observed effects. This work was supported in part by an ESPE Research Fellowship, sponsored by Novo Nordisk A/S to A.Jø. Additional funding for this project was obtained from The Research Council of the Capital Region of Denmark (E.R.-D.M.), The Research Fund at Rigshospitalet (A.Ju. and J.E.N.), Familien Erichssens Fund (A.Jø.), Dagmar Marshalls Fund (A.Jø.) and Aase & Ejnar Danielsens Fund (A.Jø.). The authors have no conflicts of interest. © The Author 2015. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

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