Sample records for jet system ss

  1. Relativistic jets in SS 433

    NASA Astrophysics Data System (ADS)

    Margon, B.

    1982-01-01

    A variety of recent optical, radio, and X-ray observations have confirmed the hypothesis that the peculiar star SS 433 is ejecting two narrow, opposed, highly collimated jets of matter at one-quarter the speed of light. This unique behavior is probably driven by mass exchange between a relatively normal star and a compact companion, either a neutron star or a black hole. However, numerous details regarding the energetics, radiation, acceleration, and collimation of the jets remain to be understood. This phenomenon may well be a miniature example of similar collimated ejection of gas by active extragalactic objects such as quasars and radio galaxies.

  2. Multi-scale virtual view on the precessing jet SS433

    NASA Astrophysics Data System (ADS)

    Monceau-Baroux, R.; Porth, O.; Meliani, Z.; Keppens, R.

    2014-07-01

    Observations of SS433 infer how an X-ray binary gives rise to a corkscrew patterned relativistic jet. XRB SS433 is well known on a large range of scales for wich we realize 3D simulation and radio mappings. For our study we use relativistic hydrodynamic in special relativity using a relativistic effective polytropic index. We use parameters extracted from observations to impose thermodynamical conditions of the ISM and jet. We follow the kinetic and thermal energy content, of the various ISM and jet regions. Our simulation follows simultaneously the evolution of the population of electrons which are accelerated by the jet. The evolving spectrum of these electrons, together with an assumed equipartition between dynamic and magnetic pressure, gives input for estimating the radio emission from our simulation. Ray tracing according to a direction of sight then realizes radio mappings of our data. Single snapshots are realised to compare with VLA observation as in Roberts et al. 2008. A radio movie is realised to compare with the 41 days movie made with the VLBA instrument. Finaly a larger scale simulation explore the discrepancy of opening angle between 10 and 20 degree between the large scale observation of SS433 and its close in observation.

  3. Nuclear processes in the jets of SS 433

    NASA Technical Reports Server (NTRS)

    Ramaty, R.; Kozlovsky, B.; Lingenfelter, R. E.

    1984-01-01

    The very narrow gamma-ray lines observed at 1.495 and 6.695 MeV from SS 433 which are blueshifted 1.369 and 6.129 emissions from deexcitations of (24)Mg-asterisk and (16)O-asterisk in grains moving with the jets and inelastically excited by interactions with the ambient medium are discussed. Energetic particle interactions in grains produce very narrow gamma ray lines from deexcitation of nuclear levels whose lifetimes are long enough that the excited nuclei stop before deexcitation. The presence of grains in the jets resolves hitherto discussed difficulties of inelastic excitation models for gamma ray production in SS 433, the very narrow widths of the observed lines and the absence of other strong lines, expected from abundant elements. A model is proposed which could be distinguished from a previously proposed fusion model by gamma ray line observations.

  4. Nuclear processes in the jets of SS433

    NASA Technical Reports Server (NTRS)

    Ramaty, R.; Kozlovsky, B.; Lingenfelter, R. E.

    1984-01-01

    The very narrow gamma-ray lines observed at 1.495 and 6.695 MeV from SS433 which are blueshifted 1.369 and 6.129 emissions from deexcitations of (24)Mg* and (16)O* in grains moving with the jets and inelastically excited by interactions with the ambient medium are discussed. Energetic particle interactions in grains produce very narrow gamma ray lines from deexcitation of nuclear levels whose lifetimes are long enough that the excited nuclei stop before deexcitation. The presence of grains in the jets resolves hitherto discussed difficulties of inelastic excitation models for gamma ray production in SS433, the very narrow widths of the observed lines and the absence of other strong lines, expected from abundant elements. A model is proposed which could be distinguished from a previously proposed fusion model by gamma ray line observations.

  5. Simulation of kinematics of SS 433 radio jets that interact with the ambient medium

    NASA Astrophysics Data System (ADS)

    Panferov, A.

    2014-02-01

    Context. The mildly relativistic jets of SS 433 are believed to inflate the surrounding supernova remnant W 50, possibly depositing more than 99% of their kinetic energy in the remnant expansion. Where and how this transformation of the energy occurs is as yet unknown. We can learn from this that the jets decelerate and that this deceleration is non-dissipative. Aims: We uncover the deviation of the arcsecond-scale precessing radio jets of SS 433 from the ballistic locus described by the kinematic model as a signature of the dynamics issuing from the interaction of the jets with the ambient medium. Methods: To do this, we simulated the kinematics of these jets, taking into account the ram pressure on the jets, which we estimated from the profile of brightness of synchrotron radiation along the radio jets, assuming pressure balance in the jets. Results: We found that to fit an observable locus in all scales the radio jets need to be decelerated and twisted in addition to the precession torsion, mostly within the first one-fifth of the precession period, and subsequently they extend in a way that imitates ballistic jets. This jet kinematics implies a smaller distance to SS 433 than the currently accepted 5.5 kpc. The physical parameters of the jet model, which links jets dynamics with radiation, are physically reliable and characteristic for the SS 433 jets. The model proposes that beyond the radio-brightening zone, the jet clouds expand because they are in pressure balance with the intercloud medium, and heat up with distance according to the law T = 2 × 104(r/1015 cm)1.5 K. Conclusions: This model naturally explains and agrees with, the observed properties of the radio jets: a) the shock-pressed morphology; b) the brightness profile; c) the ~10% deflections of the jet kinematics from the standard kinematic model - a magnitude of the jet speed decrement in our simulation; d) the precession-phase deviations from the standard kinematic model predictions; e) the

  6. Symmetry in the Changing Jets of SS 433 and Its True Distance from Us

    NASA Astrophysics Data System (ADS)

    Blundell, Katherine M.; Bowler, Michael G.

    2004-12-01

    We present the deepest yet radio image of the Galactic jet source SS 433, which reveals over two full precession cycles (>2×163 days) of the jet axis. Systematic and identifiable deviations from the traditional kinematical model for the jets are found: variations in jet speed, lasting for as long as tens of days, are necessary to match the detailed structure of each jet. It is remarkable that these variations are equal and opposite, matching the two jets simultaneously. This explains certain features of the correlated redshift residuals found in fits to the kinematic model of SS 433 reported in the literature. Asymmetries in the image caused by light-travel time enabled us to measure the jet speeds of particular points to be within a range from 0.24c to 0.28c, consistent with, yet determined independently from, the speeds derived from the famous moving optical emission lines. Taken together with the angular periodicity of the zigzag/corkscrew structure projected on the plane of the sky (produced by the precession of the jet axis), these measurements determine beyond all reasonable doubt the distance to SS 433 to be 5.5+/-0.2 kpc, significantly different from the distance most recently inferred using neutral hydrogen measurements together with the current rotation model for the Galaxy.

  7. Rapid variability of the arcsec-scale X-ray jets of SS 433

    NASA Astrophysics Data System (ADS)

    Migliari, S.; Fender, R. P.; Blundell, K. M.; Méndez, M.; van der Klis, M.

    2005-04-01

    We present X-ray images of all the available Chandra observations of the galactic jet source SS 433. We have studied the morphology of the X-ray images and inspected the evolution of the arcsec X-ray jets, recently found to be manifestations of in situ reheating of the relativistic gas downstream in the jets. The Chandra images reveal that the arcsec X-ray jets are not steady long-term structures; the structure varies, indicating that the reheating processes have no preference for a particular precession phase or distance from the binary core. Three observations made within about five days in 2001 May, and a 60-ks observation made in 2003 July, show that the variability of the jets can be very rapid, from time-scales of days to (possibly) hours. The three 2001 May images show two resolved knots in the east jet getting brighter one after the other, suggesting that a common phenomenon might be at the origin of the sequential reheatings of the knots. We discuss possible scenarios and propose a model to interpret these brightenings in terms of a propagating shock wave, revealing a second, faster outflow in the jet.

  8. Pulsar-driven Jets In Sne, Grbs, Lmxbs, Ss 433, And The Universe

    NASA Astrophysics Data System (ADS)

    Middleditch, John

    2011-05-01

    The model of pulsar emission through superluminally induced polarization currents, (SLIP), predicts that pulsations produced by such currents at many light cylinder radii by a rotating, magnetized body, will drive pulsations close to the axis of rotation. In SN 1987A, the possible Rosetta Stone for 99% of SNe, GRBs, ms pulsars, and SS 433, such highly collimated (>1 in 10,000) 2.14 ms pulsations, and the similarly collimated jets of particles which they drove, including 1e-6 solar masses with velocities 0.95 c, were responsible for its very early light curve (days 3-20), its "Mystery Spot," observed slightly later (0.5 to 0.3 c, at days 30-50 and after), and still later, in less collimated form, its bipolarity. The axially driven pulsations enforce a toroidal geometry onto all early SNRs, rendering even SNe Ia unsuitable as standard candles. The numbers for Sco X-1's jet are identical, while those for SS 433 are lower (0.26 c), because of the absence of velocity "boosting" via collisions of heavy elements with lighter ones, due to the nearly pure hydrogen content of the supercritical accretion. SLIP also drives positrons from SNe to high energies, possibly accounting for the excess seen by PAMELA at scores of GeV, and predicts that almost all pulsars with very sharp single pulses have been detected because the Earth is in a favored direction where their fluxes diminish only as 1/distance, and this has been verified in the laboratory as well as for the Parkes Multibeam Survey. SLIP also predicts that GRB afterglows will be 100% pulsed at 500 Hz in their proper frame. Finally, SLIP jets from SNe of the first stars may allow galaxies to form without the need for dark matter. This work was supported in part by the Department of Energy through the Los Alamos Directed Research Grant DR20080085.

  9. XTE Proposal #20102--"SS 433's High Energy Spectrum"

    NASA Technical Reports Server (NTRS)

    Band, David L.; Blanco, P.; Rothschild, R.; Kawai, N.; Kotani, T.; Oka, T.; Wagner, R. M.; Hjellming, R.; Rupen, M.; Brinkmann, W.

    1999-01-01

    We observed the jet-producing compact binary system SS 433 with RXTE during three multiwavelength campaigns, the first in conjunction with ASCA observations, the second simultaneous with a VLA-VLBA-MERLIN campaign, and the third associated with a Nobeyama millimeter-band campaign. All these campaigns included optical observations. Occurring at different jet precession and binary phases, the observations also monitored the system during a radio flare. The data provide SS 433's X-ray spectrum over more than an energy decade, and track the spectral variations as the X-ray source was partially eclipsed. The continuum can be modeled as a power law with an exponential cutoff, which can be detected to approximately 50 keV. Strong line emission is evident in the 5-10 keV range which can be modeled as a broad line whose energy is precession independent and a narrow line whose energy does vary with jet precession phase; this line model is clearly an over simplification since the PCA does not have sufficient energy resolution to detect the lines ASCA observed. The eclipses are deeper at high energy and at jet precession phases when the jets are more inclined towards and away from us. A large radio flare occurred between two sets of X-ray monitoring observations; an X-ray observation at the peak of the flare found a softer spectrum with a flux approximately 1/3 that of the quiescent level.

  10. Pulsar-driven Jets In Supernovae, LMXBs, SS 433, And The Universe

    NASA Astrophysics Data System (ADS)

    Middleditch, John

    2011-01-01

    The model of pulsar emission through superluminally induced polarization currents (SLIP) predicts that pulsations produced by such currents, induced at many light cylinder radii by a rotating, magnetized body, as would be the case for a neutron star born within any star of more than 1.4 solar masses, will drive pulsations close to the axis of rotation. In SN 1987A, such highly collimated (<1 in 10,000) 2.14 ms pulsations, and the similarly collimated jets of particles which they drove, including 1e-6 solar masses with velocities of up to 0.95 c, were responsible for the features of its very early light (days 3 - 20), its "Mystery Spot," observed slightly later (0.5 to 0.3 c, at days 30 - 50 and after), and still later, in less collimated form, its bipolarity. The kinematics of the jets in Sco X-1 are nearly identical, while those for SS 433 are lower (0.26 c), because of the absence of velocity "boosting" via collisions of heavy elements with lighter ones, due to the nearly pure hydrogen content of the supercritical accretion. SLIP also predicts that almost all pulsars with very sharp single pulses have been detected because the Earth is in a favored direction where their fluxes diminish only as 1/distance, and this has been verified in the laboratory as well as for the Parkes Multibeam Survey. The axially driven pulsations enforce a toroidal geometry onto all early SNRs, rendering even SNe Ia unsuitable as standard candles. SLIP also specifically predicts that gamma-ray-burst afterglows will be essentially 100% pulsed at 500 Hz in their proper frame. Finally, SLIP jets from SNe of the first stars may allow galaxies to form without the need for dark matter. This work was supported in part by the Department of Energy through the Los Alamos Directed Research Grant DR20080085.

  11. Constraints on particle acceleration in SS433/W50 from MAGIC and H.E.S.S. observations

    NASA Astrophysics Data System (ADS)

    MAGIC Collaboration; Ahnen, M. L.; Ansoldi, S.; Antonelli, L. A.; Arcaro, C.; Babić, A.; Banerjee, B.; Bangale, P.; Barres de Almeida, U.; Barrio, J. A.; Becerra González, J.; Bednarek, W.; Bernardini, E.; Berti, A.; Biasuzzi, B.; Biland, A.; Blanch, O.; Bonnefoy, S.; Bonnoli, G.; Borracci, F.; Carosi, R.; Carosi, A.; Chatterjee, A.; Colin, P.; Colombo, E.; Contreras, J. L.; Cortina, J.; Covino, S.; Cumani, P.; da Vela, P.; Dazzi, F.; de Angelis, A.; de Lotto, B.; de Oña Wilhelmi, E.; di Pierro, F.; Doert, M.; Domínguez, A.; Dominis Prester, D.; Dorner, D.; Doro, M.; Einecke, S.; Eisenacher Glawion, D.; Elsaesser, D.; Engelkemeier, M.; Fallah Ramazani, V.; Fernández-Barral, A.; Fidalgo, D.; Fonseca, M. V.; Font, L.; Fruck, C.; Galindo, D.; García López, R. J.; Garczarczyk, M.; Gaug, M.; Giammaria, P.; Godinović, N.; Gora, D.; Griffiths, S.; Guberman, D.; Hadasch, D.; Hahn, A.; Hassan, T.; Hayashida, M.; Herrera, J.; Hose, J.; Hrupec, D.; Hughes, G.; Ishio, K.; Konno, Y.; Kubo, H.; Kushida, J.; Kuveždić, D.; Lelas, D.; Lindfors, E.; Lombardi, S.; Longo, F.; López, M.; López-Oramas, A.; Majumdar, P.; Makariev, M.; Maneva, G.; Manganaro, M.; Mannheim, K.; Maraschi, L.; Mariotti, M.; Martínez, M.; Mazin, D.; Menzel, U.; Minev, M.; Mirzoyan, R.; Moralejo, A.; Moreno, V.; Moretti, E.; Munar-Adrover, P.; Neustroev, V.; Niedzwiecki, A.; Nievas Rosillo, M.; Nilsson, K.; Nishijima, K.; Noda, K.; Nogués, L.; Paiano, S.; Palacio, J.; Paneque, D.; Paoletti, R.; Paredes, J. M.; Paredes-Fortuny, X.; Pedaletti, G.; Peresano, M.; Perri, L.; Persic, M.; Prada Moroni, P. G.; Prandini, E.; Puljak, I.; Garcia, J. R.; Reichardt, I.; Rhode, W.; Ribó, M.; Rico, J.; Saito, T.; Satalecka, K.; Schroeder, S.; Schweizer, T.; Shore, S. N.; Sillanpää, A.; Sitarek, J.; Šnidarić, I.; Sobczynska, D.; Stamerra, A.; Strzys, M.; Surić, T.; Takalo, L.; Tavecchio, F.; Temnikov, P.; Terzić, T.; Tescaro, D.; Teshima, M.; Torres, D. F.; Torres-Albà, N.; Treves, A.; Vanzo, G.; Vazquez Acosta, M.; Vovk, I.; Ward, J. E.; Will, M.; Wu, M. H.; Zarić, D.; H.E.S.S. Collaboration; Abdalla, H.; Abramowski, A.; Aharonian, F.; Ait Benkhali, F.; Akhperjanian, A. G.; Andersson, T.; Angüner, E. O.; Arakawa, M.; Arrieta, M.; Aubert, P.; Backes, M.; Balzer, A.; Barnard, M.; Becherini, Y.; Becker Tjus, J.; Berge, D.; Bernhard, S.; Bernlöhr, K.; Blackwell, R.; Böttcher, M.; Boisson, C.; Bolmont, J.; Bordas, P.; Bregeon, J.; Brun, F.; Brun, P.; Bryan, M.; Büchele, M.; Bulik, T.; Capasso, M.; Carr, J.; Casanova, S.; Cerruti, M.; Chakraborty, N.; Chalme-Calvet, R.; Chaves, R. C. G.; Chen, A.; Chevalier, J.; Chrétien, M.; Coffaro, M.; Colafrancesco, S.; Cologna, G.; Condon, B.; Conrad, J.; Cui, Y.; Davids, I. D.; Decock, J.; Degrange, B.; Deil, C.; Devin, J.; Dewilt, P.; Dirson, L.; Djannati-Ataï, A.; Domainko, W.; Donath, A.; Drury, L. O.'c.; Dutson, K.; Dyks, J.; Edwards, T.; Egberts, K.; Eger, P.; Ernenwein, J.-P.; Eschbach, S.; Farnier, C.; Fegan, S.; Fernandes, M. V.; Fiasson, A.; Fontaine, G.; Förster, A.; Funk, S.; Füßling, M.; Gabici, S.; Gajdus, M.; Gallant, Y. A.; Garrigoux, T.; Giavitto, G.; Giebels, B.; Glicenstein, J. F.; Gottschall, D.; Goyal, A.; Grondin, M.-H.; Hahn, J.; Haupt, M.; Hawkes, J.; Heinzelmann, G.; Henri, G.; Hermann, G.; Hervet, O.; Hinton, J. A.; Hofmann, W.; Hoischen, C.; Holler, M.; Horns, D.; Ivascenko, A.; Iwasaki, H.; Jacholkowska, A.; Jamrozy, M.; Janiak, M.; Jankowsky, D.; Jankowsky, F.; Jingo, M.; Jogler, T.; Jouvin, L.; Jung-Richardt, I.; Kastendieck, M. A.; Katarzyński, K.; Katsuragawa, M.; Katz, U.; Kerszberg, D.; Khangulyan, D.; Khélifi, B.; Kieffer, M.; King, J.; Klepser, S.; Klochkov, D.; Kluźniak, W.; Kolitzus, D.; Komin, Nu.; Kosack, K.; Krakau, S.; Kraus, M.; Krüger, P. P.; Laffon, H.; Lamanna, G.; Lau, J.; Lees, J.-P.; Lefaucheur, J.; Lefranc, V.; Lemière, A.; Lemoine-Goumard, M.; Lenain, J.-P.; Leser, E.; Lohse, T.; Lorentz, M.; Liu, R.; López-Coto, R.; Lypova, I.; Marandon, V.; Marcowith, A.; Mariaud, C.; Marx, R.; Maurin, G.; Maxted, N.; Mayer, M.; Meintjes, P. J.; Meyer, M.; Mitchell, A. M. W.; Moderski, R.; Mohamed, M.; Mohrmann, L.; Morå, K.; Moulin, E.; Murach, T.; Nakashima, S.; de Naurois, M.; Niederwanger, F.; Niemiec, J.; Oakes, L.; O'Brien, P.; Odaka, H.; Öttl, S.; Ohm, S.; Ostrowski, M.; Oya, I.; Padovani, M.; Panter, M.; Parsons, R. D.; Pekeur, N. W.; Pelletier, G.; Perennes, C.; Petrucci, P.-O.; Peyaud, B.; Piel, Q.; Pita, S.; Poon, H.; Prokhorov, D.; Prokoph, H.; Pühlhofer, G.; Punch, M.; Quirrenbach, A.; Raab, S.; Reimer, A.; Reimer, O.; Renaud, M.; de Los Reyes, R.; Richter, S.; Rieger, F.; Romoli, C.; Rowell, G.; Rudak, B.; Rulten, C. B.; Safi-Harb, S.; Sahakian, V.; Saito, S.; Salek, D.; Sanchez, D. A.; Santangelo, A.; Sasaki, M.; Schlickeiser, R.; Schüssler, F.; Schulz, A.; Schwanke, U.; Schwemmer, S.; Seglar-Arroyo, M.; Settimo, M.; Seyffert, A. S.; Shafi, N.; Shilon, I.; Simoni, R.; Sol, H.; Spanier, F.; Spengler, G.; Spies, F.; Stawarz, Ł.; Steenkamp, R.; Stegmann, C.; Stycz, K.; Sushch, I.; Takahashi, T.; Tavernet, J.-P.; Tavernier, T.; Taylor, A. M.; Terrier, R.; Tibaldo, L.; Tiziani, D.; Tluczykont, M.; Trichard, C.; Tsuji, N.; Tuffs, R.; Uchiyama, Y.; van der Walt, D. J.; van Eldik, C.; van Rensburg, C.; van Soelen, B.; Vasileiadis, G.; Veh, J.; Venter, C.; Viana, A.; Vincent, P.; Vink, J.; Voisin, F.; Völk, H. J.; Vuillaume, T.; Wadiasingh, Z.; Wagner, S. J.; Wagner, P.; Wagner, R. M.; White, R.; Wierzcholska, A.; Willmann, P.; Wörnlein, A.; Wouters, D.; Yang, R.; Zabalza, V.; Zaborov, D.; Zacharias, M.; Zanin, R.; Zdziarski, A. A.; Zech, A.; Zefi, F.; Ziegler, A.; Zywucka, N.

    2018-04-01

    Context. The large jet kinetic power and non-thermal processes occurring in the microquasar SS 433 make this source a good candidate for a very high-energy (VHE) gamma-ray emitter. Gamma-ray fluxes above the sensitivity limits of current Cherenkov telescopes have been predicted for both the central X-ray binary system and the interaction regions of SS 433 jets with the surrounding W50 nebula. Non-thermal emission at lower energies has been previously reported, indicating that efficient particle acceleration is taking place in the system. Aim. We explore the capability of SS 433 to emit VHE gamma rays during periods in which the expected flux attenuation due to periodic eclipses (Porb 13.1 days) and precession of the circumstellar disk (Ppre 162 days) periodically covering the central binary system is expected to be at its minimum. The eastern and western SS 433/W50 interaction regions are also examined using the whole data set available. We aim to constrain some theoretical models previously developed for this system with our observations. Methods: We made use of dedicated observations from the Major Atmospheric Gamma Imaging Cherenkov telescopes (MAGIC) and High Energy Spectroscopic System (H.E.S.S.) of SS 433 taken from 2006 to 2011. These observation were combined for the first time and accounted for a total effective observation time of 16.5 h, which were scheduled considering the expected phases of minimum absorption of the putative VHE emission. Gamma-ray attenuation does not affect the jet/medium interaction regions. In this case, the analysis of a larger data set amounting to 40-80 h, depending on the region, was employed. Results: No evidence of VHE gamma-ray emission either from the central binary system or from the eastern/western interaction regions was found. Upper limits were computed for the combined data set. Differential fluxes from the central system are found to be ≲ 10-12-10-13 TeV-1 cm-2 s-1 in an energy interval ranging from few × 100 Ge

  12. Magnetic field analysis of the bow and terminal shock of the SS 433 jet

    NASA Astrophysics Data System (ADS)

    Sakemi, Haruka; Machida, Mami; Akahori, Takuya; Nakanishi, Hiroyuki; Akamatsu, Hiroki; Kurahara, Kohei; Farnes, Jamie

    2018-03-01

    We report a polarization analysis of the eastern region of W 50, observed with the Australia Telescope Compact Array (ATCA) at 1.4-3.0 GHz. In order to study the physical structures in the region where the SS 433 jet and W 50 interact, we obtain an intrinsic magnetic field vector map of that region. We find that the orientation of the intrinsic magnetic field vectors are aligned along the total intensity structures, and that there are characteristic, separate structures related to the jet, the bow shock, and the terminal shock. The Faraday rotation measures (RMs), and the results of Faraday tomography suggest that a high-intensity, filamentary structure in the north-south direction of the eastern-edge region can be separated into at least two parts to the north and south. The results of Faraday tomography also show that there are multiple components along the line of sight and/or within the beam area. In addition, we analyze the X-ray ring-like structure observed with XMM-Newton. While the possibility still remains that this X-ray ring is "real", it seems that the structure is not ring-like at radio wavelengths. Finally, we suggest that the structure is a part of the helical structure that coils the eastern ear of W 50.

  13. The Power of SS 433's Jets

    NASA Technical Reports Server (NTRS)

    Band, David F.

    1999-01-01

    We observed SS 433 for the third time with RXTE, this time simultaneously with a Nobeyama millimeter band monitoring campaign. These observations extended the RXTE coverage of SS 433's precession phases. and once again monitored the source during a binary eclipse. Our AO-2 campaign of a joint RXTE-VLBA-VLA-MERLIN observation was delayed to little more than a month before the AO-3 observations. We also had an AO-1 observation of SS 433. In each case we observed an eclipse of the compact ob'ect by the companion star, and had contemporaneous optical observations. We are analyzing all three sets of observations together. A publication is in preparation; Its completion will be supported by the remaining AO-2 funds. Here I will summarize the general results and point out the relevant features of the AO-3 observations. The spectrum is detected to approx. 50 keV, which is entirely within the PCA energy band. We find that the HEXTE data do not add significantly to the spectrum, and most of our fits are without HEXTE. We find that the continuum can be fit with a power law with an exponential cutoff; the photon index is usually approx. 1.4. A line at approx. 6.4 keV is definitely required, and the fits improve significant, if we add a second line, also with an energy in the iron K(alpha) complex, and an absorption edge. The edge usually has an energy of approx. 5.8 keV, which does not correspond to any known physical feature. and may be an instrumental artifact. This is under further investigation.

  14. AtlasT4SS: a curated database for type IV secretion systems.

    PubMed

    Souza, Rangel C; del Rosario Quispe Saji, Guadalupe; Costa, Maiana O C; Netto, Diogo S; Lima, Nicholas C B; Klein, Cecília C; Vasconcelos, Ana Tereza R; Nicolás, Marisa F

    2012-08-09

    The type IV secretion system (T4SS) can be classified as a large family of macromolecule transporter systems, divided into three recognized sub-families, according to the well-known functions. The major sub-family is the conjugation system, which allows transfer of genetic material, such as a nucleoprotein, via cell contact among bacteria. Also, the conjugation system can transfer genetic material from bacteria to eukaryotic cells; such is the case with the T-DNA transfer of Agrobacterium tumefaciens to host plant cells. The system of effector protein transport constitutes the second sub-family, and the third one corresponds to the DNA uptake/release system. Genome analyses have revealed numerous T4SS in Bacteria and Archaea. The purpose of this work was to organize, classify, and integrate the T4SS data into a single database, called AtlasT4SS - the first public database devoted exclusively to this prokaryotic secretion system. The AtlasT4SS is a manual curated database that describes a large number of proteins related to the type IV secretion system reported so far in Gram-negative and Gram-positive bacteria, as well as in Archaea. The database was created using the RDBMS MySQL and the Catalyst Framework based in the Perl programming language and using the Model-View-Controller (MVC) design pattern for Web. The current version holds a comprehensive collection of 1,617 T4SS proteins from 58 Bacteria (49 Gram-negative and 9 Gram-Positive), one Archaea and 11 plasmids. By applying the bi-directional best hit (BBH) relationship in pairwise genome comparison, it was possible to obtain a core set of 134 clusters of orthologous genes encoding T4SS proteins. In our database we present one way of classifying orthologous groups of T4SSs in a hierarchical classification scheme with three levels. The first level comprises four classes that are based on the organization of genetic determinants, shared homologies, and evolutionary relationships: (i) F-T4SS, (ii) P-T4SS, (iii

  15. First Optical observation of a microquasar at sub-milliarsec scale: SS 433 resolved by VLTI/GRAVITY

    NASA Astrophysics Data System (ADS)

    Petrucci, P.; Waisberg, I.; Lebouquin, J.; Dexter, J.; Dubus, G.; Perraut, K.; Kervella, P.; Gravity Collaboration

    2017-10-01

    We present the first Optical observation at sub-milliarcsec (mas) scale of the famous microquasar SS 433 obtained with the GRAVITY instrument on the VLTI interferometer. This observation reveals the SS 433 inner regions with unprecedent details: The K-band continuum emitting region is dominated by a marginally resolved point source (< 1 mas) embedded inside a diffuse background accounting for 10% of the total flux. The significant visibility drop across the jet lines present in the K-band spectrum, together with the small and nearly identical phases for all baselines, point toward a jet that is offset by < 0.5 mas from the continuum source and resolved in the direction of propagation, with a size of ˜2 mas. Jet emission so close to the central binary system implies that line locking, if relevant to explain the 0.26c jet velocity, operates on elements heavier than hydrogen. Concerning The Brγ line, it is better resolved than the continuum and the S-shape phase signal present across the line suggests an East-West oriented geometry alike the jet direction and supporting a (polar) disk wind origin. This observation show the potentiality of Optical interferometry to constrain the inner regions of high energy sources like microquasars.

  16. Periodicity Analysis of X-ray Light Curves of SS 433

    NASA Astrophysics Data System (ADS)

    Wang, Jun-yi; Lu, Xiang-long; Zhao, Qiu-wen; Dong, Dian-qiao; Lao, Bao-qiang; Lu, Yang; Wei, Yan-heng; Wu, Xiao-cong; An, Tao

    2017-01-01

    SS 433 is sofar the unique X-ray binary that has the simultaneously detected orbital period, super-orbital period, and nutation period, as well as a bidirectional spiral jet. The study on its X-ray light variability is helpful for understanding the dynamic process of the system, and the correlations between the different wavebands. In this paper, two time-series analysis techniques, i.e., the Lomb-Scargle periodogram and weighted wavelet Z-transform, are employed to search for the periods in the Swift/BAT (Burst Alert Telescope) (15-50 keV) and RXTE/ASM (Rose X-ray Timing Explorer/All Sky Monitor) (1.5-3, 3- 4, and 5-12 keV) light curves of SS 433, and the Monte Carlo simulation is performed for the obtained periodical components. For the 15-50 keV energy band, five significant periodical components are detected, which are P1(∼6.29 d), P2 (∼6.54 d), P3 (∼13.08 d), P4 (∼81.50 d), and P5 (∼162.30 d). For the 3-5 and 5-12 keV energy bands, the periodical components P3 (∼13 d) and P5 (∼162 d) are detected in both energy bands. However, for the 1.5-3 keV energy band, no significant periodic signal is detected. P5 is the strongest periodic signal in the power spectrum for all the energy bands of 3-5, 5-12, and 15-50 keV, and it is consistent with the previous result obtained from the study of optical light curves. Furthermore, in combination with the radio spiral jet of SS 433, it is suggested that the X-ray and optical variability of P5 (∼162 d) is probably related to the precession of its relativistic jet. The high correlation between the X-ray and optical light curves may also imply that the X-ray and optical radiations are of the same physical origin. P3 shows a good agreement with the orbital period (∼13.07 d) obtained by the previous study, and P2 and P4 are respectively the high-frequency harmonics of P3 and P5. P1 is detected only in the power spectrum of the 15-50 keV energy band, and it is consistent with the nutation period of the system. As

  17. Jets Spout Far Closer to Black Hole Than Thought, Scientists Say

    NASA Astrophysics Data System (ADS)

    2004-01-01

    Scientists at the Massachusetts Institute of Technology, taking advantage of multiple unique views of black hole particle jets over the course of a year with NASA's Chandra X-ray Observatory, have assembled a "picture" of the region that has revealed several key discoveries. They have found that the jets may be originating five times closer to the black hole than previously thought; they see in better detail how these jets change with time and distance from the black hole; and they could use this information as a new technique to measure black hole mass. Presented today in a press conference at the meeting of the American Astronomical Society in Atlanta, the observation will ultimately help solve the mystery of the great cosmic contradiction, in which black holes, notorious for pulling matter in, somehow manage to also shoot matter away in particle jets moving close to the speed of light. The observation is of a familiar source named SS 433 -- a binary star system within our Galaxy in the constellation Aquila, the Eagle, about 16,000 light years away. The black hole and its companion are about two-thirds closer to each other than the planet Mercury is to the Sun. The jets shoot off at 175 million miles per hour, 26 percent of light speed. "The high-speed jets in nearby SS 433 may be caused by the same mechanisms as the powerful outflows in the most distant and much more massive black holes, such as quasars," said Laura Lopez, an undergraduate student at MIT and lead author on a paper about the result. "SS 433 provides a nice local laboratory to study the formation of and conditions in relativistic jets." Dr. Herman Marshall, Ms. Lopez's research supervisor, led the investigation. Matter from the companion star pours into the black hole via a swirling accretion disk, much like water down a drain. Black hole particles jets are thought to be produced as some of the matter encounters strong magnetic fields close to the black hole. SS 433 is angled in such a way that

  18. SS 433: Total Coverage of 162-Day Precession Phase in Four Years

    NASA Technical Reports Server (NTRS)

    Band, David L.

    1997-01-01

    The observations prior to AO-4 covered a number of precession phases, leaving a gap at phase 0.8. In addition, ASCA and previous observations of SS 433 did not observe the spectrum above approx. 10 keV, and consequently the continuum underlying the spectral lines was poorly constrained. Therefore RXTE observations were scheduled for April 1997 to extend the observed spectrum to higher energies; these observations were planned to sample the X-ray lightcurve during the 13.08 day binary period, concentrating on the eclipse of the compact object which emits the jets. We proposed and were awarded ASCA observations simultaneous with the RXTE observations; the purpose of the ASCA observations was to provide greater spectral resolution at the low end of the spectrum observed by RXTE, and to complete the phase coverage of SS 433. As a result of scheduling difficulties early in the mission the RXTE observations were confined to a much shorter time range than originally planned, April 18-91 1997. Optical observations of SS 433 were performed at a number of observatories. The ASCA observations occurred from April 18 13:10 (UT) to April 21 13:20 (UT) for a total effective exposure of 120 ks. The continuum X-ray light curve shows that the ASCA observations started shortly before the ingress into the X-ray partial eclipse, and ended approximately at the time of the egress. Light curves were also obtained for the prominent Fe emission lines in the blue-shifted frame (approaching jet), red-shifted frame (receding jet), and the stationary frame (fluorescent line from the ambient matter). Through the eclipse mapping technique using the light curves, the parameters of the jet emission model were constrained, showing that the kinetic power in the jet exceeds 104? erg s-l. If the energy source is gravitational accretion, as is commonly believed, the derived l;inetic power implies extremely supercritical accretion even for a black; hole with 10M. These results will be described more

  19. Study of advanced communications satellite systems based on SS-FDMA

    NASA Technical Reports Server (NTRS)

    Kiesling, J.

    1980-01-01

    A satellite communication system based on the use of a multiple, contiguous beam satellite antenna and frequency division multiple access (FDMA) is studied. Emphasis is on the evaluation of the feasibility of SS (satellite switching) FDMA technology, particularly the multiple, contiguous beam antenna, the onboard switch and channelization, and on methods to overcome the effects of severe Ka band fading caused by precipitation. This technology is evaluated and plans for technology development and evaluation are given. The application of SS-FDMA to domestic satellite communications is also evaluated. Due to the potentially low cost Earth stations, SS-FDMA is particularly attractive for thin route applications up to several hundred kilobits per second, and offers the potential for competing with terrestrial facilities at low data rates and over short routes. The onboard switch also provides added route flexibility for heavy route systems. The key beneficial SS-FDMA strategy is to simplify and thus reduce the cost of the direct access Earth station at the expense of increased satellite complexity.

  20. Monitoring of Northern dwarf novae for radio jets campaign

    NASA Astrophysics Data System (ADS)

    Waagen, Elizabeth O.

    2014-10-01

    Ms. Deanne Coppejans (PhD candidate, Radboud University Nijmegen (Netherlands) and University of Cape Town) and colleagues have requested AAVSO observer assistance in monitoring nine Northern dwarf novae in support of their campaign to observe them in outburst with the Very Large Array (VLA) to search for radio jets. They will observe 5 targets from the following list: U Gem*, EX Dra, Z Cam*, RX And*, EM Cyg, AB Dra, SY Cnc, SU UMa*, and YZ Cnc*. Stars with an asterisk (*) will be given higher priority. The campaign will begin now, starting with monitoring of RX And and EM Cyg, and run through September 2015, or until all five VLA triggers have been used. This campaign is similar to previous AAVSO campaigns, namely the 2007 campaign to monitor a sample of 10 dwarf novae (AAVSO Alert Notice 345), which resulted in the first detection of a radio jet in a dwarf nova system (Koerding et al. 2008, Science, 320, 1318), and the ones carried out at the request of Dr. James Miller-Jones and colleagues on SS Cyg in 2010-2011 (AAVSO Special Notices #204, #206, Alert Notice 445). The latter resulted in an accurate distance determination to SS Cyg, thereby reconciling its behavior with our understanding of accretion disc theory in accreting compact objects (Miller-Jones et al. 2013, Science, 340, 950). Ms. Coppejans writes: "The relation between accretion and outflow is one of the basic problems in modern astrophysics. It has long been thought that CVs are the only accreting systems that do not produce jets, and this notion has even been used to constrain jet models. However, there are now some indications that CVs do show jets, possibly allowing a universal link between accretion and ejection. Radio observations provide the best unambiguous tracer of the corresponding jet or directed outflow, but there are only two clear detections. By observing a more extensive sample of cataclysmic variables in outburst we will determine the existence of jets or other outflows in these

  1. The Symbiotic System SS73 17 seen with Suzaku

    NASA Technical Reports Server (NTRS)

    Smith, Randall K.; Mushotzky, Richard; Kallman, Tim; Tueller, Jack; Mukai, Koji; Markwardt, Craig

    2007-01-01

    We observed with Suzaku the symbiotic star SS73 17, motivated by the discovery by the INTEGRAL satellite and the Swift BAT survey that it emits hard X-rays. Our observations showed a highly-absorbed X-ray spectrum with NH > loz3 emp2, equivalent to Av > 26, although the source has B magnitude 11.3 and is also bright in UV. The source also shows strong, narrow iron lines including fluorescent Fe K as well as Fe xxv and Fe XXVI. The X-ray spectrum can be fit with a thermal model including an absorption component that partially covers the source. Most of the equivalent width of the iron fluorescent line in this model can be explained as a combination of reprocessing in a dense absorber plus reflection off a white dwarf surface, but it is likely that the continuum is partially seen in reflection as well. Unlike other symbiotic systems that show hard X-ray emission (CH Cyg, RT Cru, T CrB, GX1+4), SS73 17 is not known to have shown nova-like optical variability, X-ray flashes, or pulsations, and has always shown faint soft X-ray emission. As a result, although it is likely a white dwarf, the nature of the compact object in SS73 17 is still uncertain. SS73 17 is probably an extreme example of the recently discovered and relatively small class of hard X-ray emitting symbiotic systems.

  2. Periodicity Analysis of X-ray Light Curves of SS 433

    NASA Astrophysics Data System (ADS)

    Wang, J. Y.; Lu, X. L.; Zhao, Q. W.; Dong, D. Q.; Lao, B. Q.; Lu, Y.; Wei, Y. H.; Wu, X. C.; An, T.

    2016-03-01

    soft X-ray), less periodicities are detected, which provides an evidence that the emission from high energy band (hard X-ray) comes primarily from jets, and the emission from low energy band (soft X-ray) may originate from the medium around binary systems. The multiple X-ray periods obtained from the present studies provide the necessary basis for the analysis of multi-wavelength data and the dynamics of the central engine system of SS 433.

  3. Flow cytometer jet monitor system

    DOEpatents

    Van den Engh, Ger

    1997-01-01

    A direct jet monitor illuminates the jet of a flow cytometer in a monitor wavelength band which is substantially separate from the substance wavelength band. When a laser is used to cause fluorescence of the substance, it may be appropriate to use an infrared source to illuminate the jet and thus optically monitor the conditions within the jet through a CCD camera or the like. This optical monitoring may be provided to some type of controller or feedback system which automatically changes either the horizontal location of the jet, the point at which droplet separation occurs, or some other condition within the jet in order to maintain optimum conditions. The direct jet monitor may be operated simultaneously with the substance property sensing and analysis system so that continuous monitoring may be achieved without interfering with the substance data gathering and may be configured so as to allow the front of the analysis or free fall area to be unobstructed during processing.

  4. T Pyxidis: The First Cataclysmic Variable with a Collimated Jet

    NASA Technical Reports Server (NTRS)

    Shahbaz, T.; Livio, M.; Southwell, K. A.; Charles, P. A.

    1997-01-01

    We present the first observational evidence for a collimated jet in a cataclysmic variable system; the recurrent nova T Pyxidis. Optical spectra show bipolar components of H(alpha) with velocities approx. 1400 km/s, very similar to those observed in the supersoft X-ray sources and in SS 433. We argue that a key ingredient of the formation of jets in the supersoft X-ray sources and T Pyx (in addition to an accretion disk threaded by a vertical magnetic field), is the presence of nuclear burning on the surface of the white dwarf.

  5. BER analysis of SS-WDM based FSO system for Vellore weather conditions

    NASA Astrophysics Data System (ADS)

    Prabu, K.; Charanya, S.; Jain, Mehul; Guha, Debapriya

    2017-11-01

    Spectrum Slicing Wavelength Division Multiplexing (SS-WDM) has been advanced to boost the long distance communication in FSO channel which assists immense bit rate due to its high capacity and efficiency. It is a substitute to WDM systems having multiple coherent lasers with different wavelengths which is expensive. This paper is subjected to investigate the characteristics and quality of communication links of data rate 1.56 GB/s and wavelength of 1550 nm. The SS-WDM technique has been inspected for 4, 8 and 16 channels to increase the performance of communication under various weather conditions. The proposed model is susceptible to system degradation due to turbulences where wind velocity, refractive index and height of buildings have been majorly focused. A case study has been experimented on how the height of buildings around VIT, Vellore campus interfere the transmission of light in free space. Based on the above study, the results shows that the benefits of spectrum slicing wavelength division multiplexing (SS-WDM) have been worked up on for the climatic conditions which enhance performance of system. Moreover, the graphs plotted against bit error rate (BER), attenuation and distance makes the analysis better which highlights the characteristic features of SS-WDM.

  6. Pulsar-driven Jets in Supernovae, Gamma-ray Bursts, and SS 433

    NASA Astrophysics Data System (ADS)

    Middleditch, John

    2010-05-01

    The model of pulsar emission through superluminally induced polarization currents (SLIP) predicts that pulsations produced by such currents, induced at many light cylinder radii by a rotating, magnetized body, as would be the case for a neutron star born within any star of more than 1.4 solar masses, will drive pulsations close to the axis of rotation. In SN 1987A, such highly collimated (less than 1 in 10,000) 2.14 ms pulsations, and the similarly collimated jets of particles which they drove, including 1e-6 solar masses with velocities of up to 0.95 c, were responsible for the features of its very early light (days 3 - 20), its "Mystery Spot," observed slightly later (days 30 - 50 and after), and still later, in less collimated form, its bipolarity. SLIP also explains why the 2.14 ms pulsations were more or less consistently observed between years 5.0 and 6.5, and why they eventually disappeared after year 9.0. There is no reason to suggest that this mechanism is not universally applicable to all SNe with gaseous remnants remaining, and thus SN 1987A is the Rosetta Stone for 99% of SNe, gamma-ray bursts, and millisecond pulsars, and possibly SS 433. The axially driven pulsations enforce a toroidal geometry onto all early SNRs, rendering even Ia's unsuitable as standard candles. SLIP predicts that almost all pulsars with very sharp single pulses have been detected because the Earth is in a favored direction where their fluxes diminish only as 1/distance, and this has been verified in the laboratory as well as for the Parkes Multibeam Survey. SLIP also specifically predicts that gamma-ray-burst afterglows will be essentially 100% pulsed at 500 Hz in their proper frame. This work was supported in part by the Department of Energy through the Los Alamos Directed Research Grant DR20080085.

  7. Jet-impingement heat transfer in gas turbine systems.

    PubMed

    Han, B; Goldstein, R J

    2001-05-01

    A review of jet-impingement heat transfer in gas turbine systems is presented. Characteristics of the different flow regions for submerged jets--free jet, stagnation flow, and wall jet--are reviewed. Heat transfer characteristics of both single and multiple jets are discussed with consideration of the effects of important parameters relevant to gas turbine systems including curvature of surfaces, crossflow, angle of impact, and rotation.

  8. Relativistic baryonic jets from an ultraluminous supersoft X-ray source.

    PubMed

    Liu, Ji-Feng; Bai, Yu; Wang, Song; Justham, Stephen; Lu, You-Jun; Gu, Wei-Min; Liu, Qing-Zhong; Di Stefano, Rosanne; Guo, Jin-Cheng; Cabrera-Lavers, Antonio; Álvarez, Pedro; Cao, Yi; Kulkarni, Shri

    2015-12-03

    The formation of relativistic jets by an accreting compact object is one of the fundamental mysteries of astrophysics. Although the theory is poorly understood, observations of relativistic jets from systems known as microquasars (compact binary stars) have led to a well established phenomenology. Relativistic jets are not expected to be produced by sources with soft or supersoft X-ray spectra, although two such systems are known to produce relatively low-velocity bipolar outflows. Here we report the optical spectra of an ultraluminous supersoft X-ray source (ULS) in the nearby galaxy M81 (M81 ULS-1; refs 9, 10). Unexpectedly, the spectra show blueshifted, broad Hα emission lines, characteristic of baryonic jets with relativistic speeds. These time-variable emission lines have projected velocities of about 17 per cent of the speed of light, and seem to be similar to those from the prototype microquasar SS 433 (refs 11, 12). Such relativistic jets are not expected to be launched from white dwarfs, and an origin from a black hole or a neutron star is hard to reconcile with the persistence of M81 ULS-1's soft X-rays. Thus the unexpected presence of relativistic jets in a ULS challenges canonical theories of jet formation, but might be explained by a long-speculated, supercritically accreting black hole with optically thick outflows.

  9. Jet pump-drive system for heat removal

    NASA Technical Reports Server (NTRS)

    French, J. R. (Inventor)

    1985-01-01

    A jet pump, in combination with a TEMP, is employed to assure safe cooling of a nuclear reactor after shutdown. A TEMP, responsive to the heat from the coolant in the secondary flow path, automatically pumps the withdrawn coolant to a higher pressure and thus higher velocity compared to the main flow. The high velocity coolant is applied as a driver flow for the jet pump which has a main flow chamber located in the main flow circulation pump. Upon nuclear shutdown and loss of power for the main reactor pumping system, the TEMP/jet pump combination continues to boost the coolant flow in the direction it is already circulating. During the decay time for the nuclear reactor, the jet pump keeps running until the coolant temperature drops to a lower and safe temperature. At this lower temperature, the TEMP/jet jump combination ceases its circulation boosting operation. The TEMP/jet pump combination is automatic, self-regulating and provides an emergency pumping system free of moving parts.

  10. Alterations in hypothalamic KiSS-1 system in experimental diabetes: early changes and functional consequences.

    PubMed

    Castellano, J M; Navarro, V M; Roa, J; Pineda, R; Sánchez-Garrido, M A; García-Galiano, D; Vigo, E; Dieguez, C; Aguilar, E; Pinilla, L; Tena-Sempere, M

    2009-02-01

    Using long-term streptozotocin (STZ)-treated male rats, we recently proposed that defective function of hypothalamic KiSS-1 system is mechanistically relevant for central hypogonadotropism of uncontrolled diabetes. However, the temporal pattern of such defects and its potential contribution to disturbed gonadotropin secretion in the diabetic female remain so far unexplored. To cover these issues, expression analyses and hormonal tests were conducted in diabetic male (1 wk after STZ; short term) and female (4 wk after STZ; long term) rats. Short-term diabetic males had lower basal testosterone levels and decreased gonadotropin responses to orchidectomy (ORX), which associated with significantly attenuated post-ORX rises of hypothalamic KiSS-1 mRNA. Yet kisspeptin administration to diabetic males was able to acutely elicit supramaximal LH and testosterone responses and normalize post-ORX gonadotropin secretion. Long-term diabetic females showed persistent anestrus and significantly decreased basal gonadotropin levels as well as blunted LH responses to ovariectomy; changes that were linked to lowering of basal and postovariectomy expression of hypothalamic KiSS-1 mRNA. Moreover, despite prevailing gonadotropin suppression, LH responses to acute kisspeptin administration were fully preserved, and even enhanced after its repeated injection, in diabetic females. In sum, our present findings further define the temporal course and mechanistic relevance of altered hypothalamic KiSS-1 system in the hypogonadotropic state of uncontrolled diabetes. Furthermore, our data provide the basis for the potential therapeutic intervention of the KiSS-1 system as adjuvant in the management of disturbed gonadotropin secretion of type 1 diabetes in the female.

  11. Jet pump-drive system for heat removal

    NASA Technical Reports Server (NTRS)

    French, James R. (Inventor)

    1987-01-01

    The invention does away with the necessity of moving parts such as a check valve in a nuclear reactor cooling system. Instead, a jet pump, in combination with a TEMP, is employed to assure safe cooling of a nuclear reactor after shutdown. A main flow exists for a reactor coolant. A point of withdrawal is provided for a secondary flow. A TEMP, responsive to the heat from said coolant in the secondary flow path, automatically pumps said withdrawn coolant to a higher pressure and thus higher velocity compared to the main flow. The high velocity coolant is applied as a driver flow for the jet pump which has a main flow chamber located in the main flow circulation pump. Upon nuclear shutdown and loss of power for the main reactor pumping system, the TEMP/jet pump combination continues to boost the coolant flow in the direction it is already circulating. During the decay time for the nuclear reactor, the jet pump keeps running until the coolant temperature drops to a lower and safe temperature where the heat is no longer a problem. At this lower temperature, the TEMP/jet pump combination ceases its circulation boosting operation. When the nuclear reactor is restarted and the coolant again exceeds the lower temperature setting, the TEMP/jet pump automatically resumes operation. The TEMP/jet pump combination is thus automatic, self-regulating and provides an emergency pumping system free of moving parts.

  12. X-ray variability of SS 433: Evidence for supercritical accretion

    NASA Astrophysics Data System (ADS)

    Atapin, K. E.; Fabrika, S. N.

    2016-08-01

    We study the X-ray variability of SS 433 based on data from the ASCA observatory and the MAXI and RXTE/ASM monitoring missions. Based on the ASCA data, we have constructed the power spectrum of SS 433 in the frequency range from 10-6 to 0.1 Hz, which confirms the presence of a flat portion in the spectrum at frequencies 3 × 10-5-10-3 Hz. The periodic variability (precession, nutation, eclipses) begins to dominate significantly over the stochastic variability at lower frequencies, which does not allow the stochastic variability to be studied reliably. The model in which the flat portion extends to 9.5 × 10-6 Hz, while a power-law rise with an index of 2.6 occurs below provides the best agreement with the observations. The nutational oscillations of the jets with a period of about three days suggests that the time for the passage of material through the disk is less than this value. At frequencies below 4 × 10-6 Hz, the shape of the power spectrum probably does not reflect the disk structure but is determined by external factors, for example, by a change in the amount of material supplied by the donor. The flat portion can arise from a rapid decrease in the viscous time in the supercritical or radiative disk zones. The flat spectrum is associated with the variability of the X-ray jets that are formed in the supercritical disk region.

  13. Radio-emitting component kinematics in SS433

    NASA Astrophysics Data System (ADS)

    Stirling, A. M.; Jowett, F. H.; Spencer, R. E.; Paragi, Z.; Ogley, R. N.; Cawthorne, T. V.

    2002-12-01

    SS433 is a galactic X-ray binary source, variable across most wavelengths of observation. On arcsecond-scales the radio emission is composed of a bright core and the famous bipolar `corkscrew' radio jets. A series of MERLIN observations at 5 GHz were taken in 1991 December and 1992 January. The emission from the radio jet was categorized by replacing discrete features with Gaussian flux-density profiles. These fitted components were used to derive proper motions, ejection position-angles and ejection dates for evolving features in the jets. The observed component position-angles and ejection dates were compared to those predicted by the kinematic model of epoch 1989. The position-angle of the precession cone was refined to . A discrepancy was discovered in the observed precessional phase which was leading that of the kinematic model by 7-10 d. This observed discrepancy was in agreement with a transient deviation in precessional phase as measured by the redshifts of optical bullets at a similar time. Analysis of the proper motions of all the fitted components leads to a distance measurement of 4.61 +/- 0.35 pc. A pair of symmetrically ejected knots with a velocity much lower than 0.26c were also discovered. Their ejection time overlapped with a period of unusual Doppler shift residuals and fragmentation of optical bullets. These events may represent the first evidence for an interaction between radio components and optical bullets.

  14. Implications of Upwells as Hydrodynamic Jets in a Pulse Jet Mixed System

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pease, Leonard F.; Bamberger, Judith A.; Minette, Michael J.

    This report evaluates the physics of the upwell flow in pulse jet mixed systems in the Hanford Tank Waste Treatment and Immobilization Plant (WTP). Although the initial downward flow and radial flow from jets characteristic of pulse jet mixers (PJMs) has been analyzed, the upwells have received considerably less attention despite having significant implications for vessel mixing. Do the upwells behave like jets? How do the upwells scale? When will the central upwell break through? What proportion of the vessel is blended by the upwells themselves? Indeed, how the physics of the central upwell is affected by multiple PJMs (e.g.,more » six in the proposed mixing vessels), non-Newtonian rheology, and significant multicomponent solids loadings remain unexplored.« less

  15. Bithermal Low-Cycle Fatigue Evaluation of Automotive Exhaust System Alloy SS409

    NASA Technical Reports Server (NTRS)

    Lu, Gui-Ying; Behling, Mike B.; Halford, Gary R.

    2000-01-01

    This investigation provides, for the first time, cyclic strainrange-controlled, thermomechanical fatigue results for the ferritic stainless steel alloy SS409. The alloy has seen extensive application for automotive exhaust system components. The data were generated to calibrate the Total Strain Version of the Strainrange Partitioning (TS-SRP) method for eventual application to the design and durability assessment of automotive exhaust systems. The thermomechanical cyclic lifetime and cyclic stress-strain constitutive behavior for alloy SS409 were measured using bithermal tests cycling between isothermal extremes of 400 and 800 C. Lives ranged up to 10,000 cycles to failure with hold-times of 0.33 to 2.0 minutes. The bithermal fatigue behavior is compared to isothermal, strain-controlled fatigue behavior at both 400 and 800 C. Thermomechanical cycling was found to have a profound detrimental influence on the fatigue failure resistance of SS409 compared to isothermal cycling. Supplementary bithermal cyclic stress-strain constitutive tests with hold-times ranging from 40 seconds up to 1.5 hours were conducted to calibrate the TS-SRP equation for extrapolation to longer lifetime predictions. Observed thermomechanical (bithermal) fatigue lives correlated well with lives calculated using the calibrated TS-SRP equations: 70% of the bithermal fatigue data fall within a factor of 1.2 of calculated life; 85% within a factor of 1.4; and 100% within a factor of 1.8.

  16. X-ray Jets in the CH Cyg Symbiotic System

    NASA Astrophysics Data System (ADS)

    Karovska, Margarita; Gaetz, T.; Lee, N.; Raymond, J.; Hack, W.; Carilli, C.

    2009-09-01

    Symbiotic binaries are interacting systems in which a compact stellar source accretes matter from the wind of the cool evolved companion. There are a few hundred symbiotic systems known today, but jet activity has been detected in only a few of them, including in CH Cyg. CH Cyg is a symbiotic system that has shown significant activity since the mid 1960s. Jets have been detected in optical and radio since 1984, and more recently in 2001 in X-rays using Chandra observations.In 2008 we carried out coordinated multi-wavelength observations of the CH Cyg system with Chandra, HST, and the VLA, in order to study the propagation and interaction with the circumbinary medium of the jet detected in 2001. We report here on the detection of the 2001 SE jet which has expanded in seven years from ˜350AU to ˜1400 AU. The apex of the loop delineating the region of interaction with the circumbinary matter is moving with a speed of ˜700 km/s. Assuming a linear expansion, the jet was launched during the 1999-2000 active phase. We also report on a detection of a powerful new jet in the SW direction, observed in X-ray, optical and radio wavelengths. The new jet has a multi-component structure including an inner jet and counter jet, and a SW component ending in several clumps extending up to a distance of about 750AU.

  17. 21 CFR 876.4650 - Water jet renal stone dislodger system.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Water jet renal stone dislodger system. 876.4650... (CONTINUED) MEDICAL DEVICES GASTROENTEROLOGY-UROLOGY DEVICES Surgical Devices § 876.4650 Water jet renal stone dislodger system. (a) Identification. A water jet renal stone dislodger system is a device used to...

  18. 21 CFR 876.4650 - Water jet renal stone dislodger system.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Water jet renal stone dislodger system. 876.4650... (CONTINUED) MEDICAL DEVICES GASTROENTEROLOGY-UROLOGY DEVICES Surgical Devices § 876.4650 Water jet renal stone dislodger system. (a) Identification. A water jet renal stone dislodger system is a device used to...

  19. [Study and development of a new automatic suction system (SS) of intratracheal sputum in order to improve QOL of many patients with tracheostomy mechanical ventilation (TMV) and their family members by this new autonomic SS].

    PubMed

    Hokezu, Youichi; Yamamoto, Makoto; Tokunaga, Syuichi; Niikura, Makoto; Nagamatsu, Keiji; Kira, Jun-ichi; Fukunaga, Toshihide; Shima, Kouji; Kikuchi, Seiji; Kimura, Itaru; Kondo, Kiyohiko; Mori, Teruhiko; Goto, Katumasa; Takigami, Shigeru; Shioya, Keiichi; Uehara, Minako

    2009-11-01

    In Japan, many patients equipped with TMV are under medical treatment at home after 1990. These patients can't put out sputa in trachea, so that these patient's family members must suck these patient's intratracheal sputa all days. Mr Yamamoto and Mr Tokunaga, main researchers of this study, began the study on the automatic SS of itratracheal sputa from 1999. In first stage, They developed the intermittent SS in detaining the suction tube within tracheal cannula, monitering the intratracheal pressure, but this system takes the ventilation away from the patient. Hypoventilation caused by this SS may cause the serious accident in patient. Therefore, we remodel the SS from intermittent SS to rollerpomp-type SS continuing to suck the itratracheal sputa with low volume from 2004, and thereafter we made up the SS of piston pomp type-SS finally at 2007. We developed the tracheal cannula with double suction holes of inner and lower hole in the lower part of its cannula together with the suction machine. We think that the practical use of this automatic SS will bring these patients with TMV and their family members great benefits. We desire that the practical use of this SS will be realized as soon as possible.

  20. Lighting system with thermal management system having point contact synthetic jets

    DOEpatents

    Arik, Mehmet; Weaver, Stanton Earl; Kuenzler, Glenn Howard; Wolfe, Jr., Charles Franklin; Sharma, Rajdeep

    2013-12-10

    Lighting system having unique configurations are provided. For instance, the lighting system may include a light source, a thermal management system and driver electronics, each contained within a housing structure. The light source is configured to provide illumination visible through an opening in the housing structure. The thermal management system includes a plurality of synthetic jets. The synthetic jets are arranged within the lighting system such that they are secured at contact points.

  1. Lighting system with thermal management system having point contact synthetic jets

    DOEpatents

    Arik, Mehmet; Weaver, Stanton Earl; Kuenzler, Glenn Howard; Wolfe, Jr, Charles Franklin; Sharma, Rajdeep

    2016-08-30

    Lighting systems having unique configurations are provided. For instance, the lighting system may include a light source, a thermal management system and driver electronics, each contained within a housing structure. The light source is configured to provide illumination visible through an opening in the housing structure. The thermal management system includes a plurality of synthetic jets. The synthetic jets are arranged within the lighting system such that they are secured at contact points.

  2. Lighting system with thermal management system having point contact synthetic jets

    DOEpatents

    Arik, Mehmet; Weaver, Stanton Earl; Kuenzler, Glenn Howard; Wolfe, Jr., Charles Franklin; Sharma, Rajdeep

    2016-08-23

    Lighting systems having unique configurations are provided. For instance, the lighting system may include a light source, a thermal management system and driver electronics, each contained within a housing structure. The light source is configured to provide illumination visible through an opening in the housing structure. The thermal management system includes a plurality of synthetic jets. The synthetic jets are arranged within the lighting system such that they are secured at contact points.

  3. Spectroscopic monitoring of SS 433: A search for long-term variations of kinematic model parameters

    NASA Astrophysics Data System (ADS)

    Davydov, V. V.; Esipov, V. F.; Cherepashchuk, A. M.

    2008-06-01

    Between 1994 and 2006, we obtained uniform spectroscopic observations of SS 433 in the region of H α. We determined Doppler shifts of the moving emission lines, H α + and H α -, and studied various irregularities in the profiles for the moving emission lines. The total number of Doppler shifts measured in these 13 years is 488 for H α - and 389 for H α +. We have also used published data to study possible long-term variations of the SS 433 system, based on 755 Doppler shifts for H α - and 630 for H α + obtained over 28 years. We have derived improved kinematic model parameters for the precessing relativistic jets of S S 433 using five-and eight-parameter models. On average, the precession period was stable during the 28 years of observations (60 precession cycles), at 162.250d ± 0.003d. Phase jumps of the precession period and random variations of its length with amplitudes of ≈6% and ≈1%, respectively, were observed, but no secular changes in the precession period were detected. The nutation period, P nut = 6.2876d ± 0.00035d, and its phase were stable during 28 years (more than 1600 nutation cycles). We find no secular variations of the nutation cycle. The ejection speed of the relativistic jets, v, was, on average, constant during the 28 years, β = v/c = 0.2561 ± 0.0157. No secular variation of β is detected. In general, S S 433 demonstrates remarkably stable long-term characteristics of its precession and nutation, as well as of the central “engine” near the relativistic object that collimates the plasma in the jets and accelerates it to v = 0.2561 c. Our results support a model with a “slaved” accretion disk in S S 433, which follows the precession of the optical star’s rotation axis.

  4. Type-IVC Secretion System: A Novel Subclass of Type IV Secretion System (T4SS) Common Existing in Gram-Positive Genus Streptococcus

    PubMed Central

    Chen, Chen; Gao, George F.

    2012-01-01

    A growing number of pathogens are being found to possess specialized secretion systems which they use in various ways to subvert host defenses. Type IV secretion system (T4SS) is one of versatile secretion systems essential for the virulence and even survival of some bacteria species, and they enable the secretion of protein and DNA substrates across the cell envelope. T4SS was once believed to be present only in Gram-negative bacteria. In this study, we present evidence of a new subclass of T4SS, Type-IVC secretion system and indicate its common existence in the Gram-positive bacterial genus Streptococcus. We further identified that VirB1, VirB4, VirB6 and VirD4 are the minimal key components of this system. Using genome comparisons and evolutionary relationship analysis, we proposed that Type-IVC secretion system is movable via transposon factors and mediates the conjugative transfer of DNA, enhances bacterial pathogenicity, and could cause large-scale outbreaks of infections in humans. PMID:23056296

  5. Spectroscopic Observations of the Mass Donor Star in SS 433

    NASA Astrophysics Data System (ADS)

    Hillwig, T. C.; Gies, D. R.

    2008-03-01

    The microquasar SS 433 is an interacting massive binary consisting of an evolved mass donor and a compact companion that ejects relativistic jets. The mass donor was previously identified through spectroscopic observations of absorption lines in the blue part of the spectrum that showed Doppler shifts associated with orbital motion and strength variations related to the orbital modulation of the star-to-disk flux ratio and to disk obscuration. However, subsequent observations revealed other absorption features that lacked these properties and that were probably formed in the disk gas outflow. We present follow-up observations of SS 433 at orbital and precession phases identical to those from several previous studies, with the goals of confirming the detection of the mass donor spectrum and providing more reliable masses for the two system components. We show that the absorption features present as well as those previously observed almost certainly belong to the mass donor star, and find revised masses of 12.3 ± 3.3 and 4.3 ± 0.8 M⊙ for the mass donor and compact object, respectively. Based on observations obtained at the Gemini Observatory, which is operated by the Association of Universities for Research in Astronomy, Inc., under a cooperative agreement with the NSF on behalf of the Gemini partnership: the National Science Foundation (US), the Science and Technology Facilities Council (UK), the National Research Council (Canada), CONICYT (Chile), the Australian Research Council (Australia), CNPq (Brazil), and SECYT (Argentina).

  6. System identification of jet engines

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sugiyama, N.

    2000-01-01

    System identification plays an important role in advanced control systems for jet engines, in which controls are performed adaptively using data from the actual engine and the identified engine. An identification technique for jet engine using the Constant Gain Extended Kalman Filter (CGEKF) is described. The filter is constructed for a two-spool turbofan engine. The CGEKF filter developed here can recognize parameter change in engine components and estimate unmeasurable variables over whole flight conditions. These capabilities are useful for an advanced Full Authority Digital Electric Control (FADEC). Effects of measurement noise and bias, effects of operating point and unpredicted performancemore » change are discussed. Some experimental results using the actual engine are shown to evaluate the effectiveness of CGEKF filter.« less

  7. Role of jet spacing and strut geometry on the formation of large scale structures and mixing characteristics

    NASA Astrophysics Data System (ADS)

    Soni, Rahul Kumar; De, Ashoke

    2018-05-01

    The present study primarily focuses on the effect of the jet spacing and strut geometry on the evolution and structure of the large-scale vortices which play a key role in mixing characteristics in turbulent supersonic flows. Numerically simulated results corresponding to varying parameters such as strut geometry and jet spacing (Xn = nDj such that n = 2, 3, and 5) for a square jet of height Dj = 0.6 mm are presented in the current study, while the work also investigates the presence of the local quasi-two-dimensionality for the X2(2Dj) jet spacing; however, the same is not true for higher jet spacing. Further, the tapered strut (TS) section is modified into the straight strut (SS) for investigation, where the remarkable difference in flow physics is unfolded between the two configurations for similar jet spacing (X2: 2Dj). The instantaneous density and vorticity contours reveal the structures of varying scales undergoing different evolution for the different configurations. The effect of local spanwise rollers is clearly manifested in the mixing efficiency and the jet spreading rate. The SS configuration exhibits excellent near field mixing behavior amongst all the arrangements. However, in the case of TS cases, only the X2(2Dj) configuration performs better due to the presence of local spanwise rollers. The qualitative and quantitative analysis reveals that near-field mixing is strongly affected by the two-dimensional rollers, while the early onset of the wake mode is another crucial parameter to have improved mixing. Modal decomposition performed for the SS arrangement sheds light onto the spatial and temporal coherence of the structures, where the most dominant structures are found to be the von Kármán street vortices in the wake region.

  8. Kidney Disease among Patients with Sickle Cell Disease, Hemoglobin SS and SC

    PubMed Central

    Drawz, Paul; Ayyappan, Sabarish; Nouraie, Mehdi; Saraf, Santosh; Gordeuk, Victor; Hostetter, Thomas; Gladwin, Mark T.

    2016-01-01

    Background and objectives Sickle cell disease (SCD) is an inherited anemia that afflicts millions worldwide. Kidney disease is a major contributor to its morbidity and mortality. We examined contemporary and historical SCD populations to understand how renal disease behaved in hemoglobin SS (HbSS) compared with HbSC. Design, setting, participants, & measurements Kidney function was examined in the multicentered Treatment of Pulmonary Hypertension and Sickle Cell Disease with Sildenafil Therapy (Walk-PHaSST) Trial (HbSS=463; HbSC=127; years 2007–2009) and historical comparator populations from the Cooperative Study of Sickle Cell Disease (CSSCD; HbSS=708) and the Multicenter Study of Hydroxyurea in Sickle Cell Disease (MSH; HbSS=299). Results In adults with SCD, eGFR was lower among older individuals: −1.78 ml/min per 1.73 m2 per year of age (95% confidence interval [95% CI], −2.06 to −1.50; Walk-PHaSST Trial), −1.75 ml/min per 1.73 m2 per year of age (95% CI, −2.05 to −1.44; MSH), and −1.69 ml/min per 1.73 m2 per year of age (95% CI, −2.00 to −1.38; CSSCD) in HbSS compared with −1.09 ml/min per 1.73 m2 per year of age (95% CI, −1.39 to −0.75) in HbSC (Walk-PHaSST Trial). Macroalbuminuria was seen in 20% of participants with SCD (HbSS or HbSC; P=0.45; Walk-PHaSST Trial), but microalbuminuria was more prevalent in HbSS (44% versus 23% in HbSC; P<0.002). In the Walk-PHaSST Trial, albuminuria was associated with hemolysis (higher lactate dehydrogenase, P<0.001; higher absolute reticulocyte count, P<0.02; and lower Hb, P=0.07) and elevated systolic BP (P<0.001) in HbSS. One half of all participants with HbSS (20 of 39) versus one fifth without (41 of 228) elevated tricuspid regurgitant jet velocity (≥3 m/s; adverse prognostic indicator in SCD) had macroalbuminuria (P<0.001). In the CSSCD, overt proteinuria, detected (less sensitively) by urine dipstick, associated with higher 3-year mortality (odds ratio, 2.48; 95% CI, 1.07 to 5.77). Serum

  9. The Type IX Secretion System (T9SS): Highlights and Recent Insights into Its Structure and Function

    PubMed Central

    Lasica, Anna M.; Ksiazek, Miroslaw; Madej, Mariusz; Potempa, Jan

    2017-01-01

    Protein secretion systems are vital for prokaryotic life, as they enable bacteria to acquire nutrients, communicate with other species, defend against biological and chemical agents, and facilitate disease through the delivery of virulence factors. In this review, we will focus on the recently discovered type IX secretion system (T9SS), a complex translocon found only in some species of the Bacteroidetes phylum. T9SS plays two roles, depending on the lifestyle of the bacteria. It provides either a means of movement (called gliding motility) for peace-loving environmental bacteria or a weapon for pathogens. The best-studied members of these two groups are Flavobacterium johnsoniae, a commensal microorganism often found in water and soil, and Porphyromonas gingivalis, a human oral pathogen that is a major causative agent of periodontitis. In P. gingivalis and some other periodontopathogens, T9SS translocates proteins, especially virulence factors, across the outer membrane (OM). Proteins destined for secretion bear a conserved C-terminal domain (CTD) that directs the cargo to the OM translocon. At least 18 proteins are involved in this still enigmatic process, with some engaged in the post-translational modification of T9SS cargo proteins. Upon translocation across the OM, the CTD is removed by a protease with sortase-like activity and an anionic LPS is attached to the newly formed C-terminus. As a result, a cargo protein could be secreted into the extracellular milieu or covalently attached to the bacterial surface. T9SS is regulated by a two-component system; however, the precise environmental signal that triggers it has not been identified. Exploring unknown systems contributing to bacterial virulence is exciting, as it may eventually lead to new therapeutic strategies. During the past decade, the major components of T9SS were identified, as well as hints suggesting the possible mechanism of action. In addition, the list of characterized cargo proteins is

  10. SynBioSS-aided design of synthetic biological constructs.

    PubMed

    Kaznessis, Yiannis N

    2011-01-01

    We present walkthrough examples of using SynBioSS to design, model, and simulate synthetic gene regulatory networks. SynBioSS stands for Synthetic Biology Software Suite, a platform that is publicly available with Open Licenses at www.synbioss.org. An important aim of computational synthetic biology is the development of a mathematical modeling formalism that is applicable to a wide variety of simple synthetic biological constructs. SynBioSS-based modeling of biomolecular ensembles that interact away from the thermodynamic limit and not necessarily at steady state affords for a theoretical framework that is generally applicable to known synthetic biological systems, such as bistable switches, AND gates, and oscillators. Here, we discuss how SynBioSS creates links between DNA sequences and targeted dynamic phenotypes of these simple systems. Copyright © 2011 Elsevier Inc. All rights reserved.

  11. Cavitating Jet Method and System for Oxygenation of Liquids

    NASA Technical Reports Server (NTRS)

    Chahine, Georges L.

    2012-01-01

    Reclamation and re-use of water is critical for space-based life support systems. A number of functions must be performed by any such system including removal of various contaminants and oxygenation. For long-duration space missions, this must be done with a compact, reliable system that requires little or no use of expendables and minimal power. DynaJets cavitating jets can oxidize selected organic compounds with much greater energy efficiency than ultrasonic devices typically used in sonochemistry. The focus of this work was to develop cavitating jets to simultaneously accomplish the functions of oxygenation and removal of contaminants of importance to space-structured water reclamation systems. The innovation is a method to increase the concentration of dissolved oxygen or other gasses in a liquid. It utilizes a particular form of novel cavitating jet operating at low to moderate pressures to achieve a high-efficiency means of transporting and mixing the gas into the liquid. When such a jet is utilized to simultaneously oxygenate the liquid and to oxidize organic compounds within the liquid, such as those in waste water, the rates of contaminant removal are increased. The invention is directed toward an increase in the dissolved gas content of a liquid, in general, and the dissolved oxygen content of a liquid in particular.

  12. Molecular determinants of the interactions between proteins and ssDNA.

    PubMed

    Mishra, Garima; Levy, Yaakov

    2015-04-21

    ssDNA binding proteins (SSBs) protect ssDNA from chemical and enzymatic assault that can derail DNA processing machinery. Complexes between SSBs and ssDNA are often highly stable, but predicting their structures is challenging, mostly because of the inherent flexibility of ssDNA and the geometric and energetic complexity of the interfaces that it forms. Here, we report a newly developed coarse-grained model to predict the structure of SSB-ssDNA complexes. The model is successfully applied to predict the binding modes of six SSBs with ssDNA strands of lengths of 6-65 nt. In addition to charge-charge interactions (which are often central to governing protein interactions with nucleic acids by means of electrostatic complementarity), an essential energetic term to predict SSB-ssDNA complexes is the interactions between aromatic residues and DNA bases. For some systems, flexibility is required from not only the ssDNA but also, the SSB to allow it to undergo conformational changes and the penetration of the ssDNA into its binding pocket. The association mechanisms can be quite varied, and in several cases, they involve the ssDNA sliding along the protein surface. The binding mechanism suggests that coarse-grained models are appropriate to study the motion of SSBs along ssDNA, which is expected to be central to the function carried out by the SSBs.

  13. Collisional-radiative simulations of a supersonic and radiatively cooled aluminum plasma jet

    NASA Astrophysics Data System (ADS)

    Espinosa, G.; Gil, J. M.; Rodriguez, R.; Rubiano, J. G.; Mendoza, M. A.; Martel, P.; Minguez, E.; Suzuki-Vidal, F.; Lebedev, S. V.; Swadling, G. F.; Burdiak, G.; Pickworth, L. A.; Skidmore, J.

    2015-12-01

    A computational investigation based on collisional-radiative simulations of a supersonic and radiatively cooled aluminum plasma jet is presented. The jet, both in vacuum and in argon ambient gas, was produced on the MAGPIE (Mega Ampere Generator for Plasma Implosion Experiments) generator and is formed by ablation of an aluminum foil driven by a 1.4 MA, 250 ns current pulse in a radial foil Z-pinch configuration. In this work, population kinetics and radiative properties simulations of the jet in different theoretical approximations were performed. In particular, local thermodynamic equilibrium (LTE), non-LTE steady state (SS) and non-LTE time dependent (TD) models have been considered. This study allows us to make a convenient microscopic characterization of the aluminum plasma jet.

  14. Mathematical Model of the Jet Engine Fuel System

    NASA Astrophysics Data System (ADS)

    Klimko, Marek

    2015-05-01

    The paper discusses the design of a simplified mathematical model of the jet (turbo-compressor) engine fuel system. The solution will be based on the regulation law, where the control parameter is a fuel mass flow rate and the regulated parameter is the rotational speed. A differential equation of the jet engine and also differential equations of other fuel system components (fuel pump, throttle valve, pressure regulator) will be described, with respect to advanced predetermined simplifications.

  15. Baseband processor development/test performance for 30/20 GHz SS-TDMA communication system

    NASA Technical Reports Server (NTRS)

    Brown, L.; Sabourin, D.; Attwood, S.

    1984-01-01

    The baseband processor (BBP) development for the 30/20 GHz Satellite Communication System is described. The SS-TDMA concept for future satellite communications is reviewed, describing the overall system, the satellite payload, and the frequency plan. A brief general description of the BBP is given, and the proof-of-concept model of the BBP is summarized. Key technologies and custom LSI developed for the BBP are listed. Finally, key technology developments and test data are reported for the BBP.

  16. The 113 GHz ECRH system for JET

    NASA Astrophysics Data System (ADS)

    Verhoeven, A. G. A.; Bongers, W. A.; Elzendoorn, B. S. Q.; Graswinckel, M.; Hellingman, P.; Kamp, J. J.; Kooijman, W.; Kruijt, O. G.; Maagdenberg, J.; Ronden, D.; Stakenborg, J.; Sterk, A. B.; Tichler, J.; Alberti, S.; Goodman, T.; Henderson, M.; Hoekzema, J. A.; Oosterbeek, J. W.; Fernandez, A.; Likin, K.; Bruschi, A.; Cirant, S.; Novak, S.; Piosczyk, B.; Thumm, M.; Bindslev, H.; Kaye, A.; Fleming, C.; Zohm, H.

    2003-02-01

    An ECRH (Electron Cyclotron Resonance Heating) system has been designed for JET in the framework of the JET Enhanced-Performance project (JET-EP) under the European Fusion Development Agreement (EFDA). Due to financial constraints it has recently been decided not to implement this project. Nevertheless, the design work conducted from April 2000 to January 2002 shows a number of features that can be relevant in preparation of future ECRH systems, e.g., for ITER. The ECRH system was foreseen to comprise 6 gyrotrons, 1 MW each, in order to deliver 5 MW into the plasma [1]. The main aim was to enable the control of neo-classical tearing modes (NTM). The paper will concentrate on: • The power-supply and modulation system, including series IGBT switches, to enable independent control of each gyrotron and an all-solid-state body power supply to stabilise the gyrotron output power and to enable fast modulations up to 10 kHz. • A plug-in launcher, that is steerable in both toroidal and poloidal angle, and able to handle 8 separate mm-wave beams. Four steerable launching mirrors were foreseen to handle two mm-wave beams each. Water cooling of all the mirrors was a particularly ITER relevant feature.

  17. The design of an ECRH system for JET-EP

    NASA Astrophysics Data System (ADS)

    Verhoeven, A. G. A.; Bongers, W. A.; Elzendoorn, B. S. Q.; Graswinckel, M.; Hellingman, P.; Kooijman, W.; Kruijt, O. G.; Maagdenberg, J.; Ronden, D.; Stakenborg, J.; Sterk, A. B.; Tichler, J.; Alberti, S.; Goodman, T.; Henderson, M.; Hoekzema, J. A.; Oosterbeek, J. W.; Fernandez, A.; Likin, K.; Bruschi, A.; Cirant, S.; Novak, S.; Piosczyk, B.; Thumm, M.; Bindslev, H.; Kaye, A.; Fleming, C.; Zohm, H.

    2003-11-01

    An electron cyclotron resonance heating (ECRH) system has been designed for JET in the framework of the JET enhanced performance project (JET-EP) under the European fusion development agreement. Due to financial constraints it has been decided not to implement this project. Nevertheless, the design work conducted from April 2000 to January 2002 shows a number of features that can be relevant in preparation of future ECRH systems, e.g. for ITER. The ECRH system was foreseen to comprise six gyrotrons, 1 MW each, in order to deliver 5 MW into the plasma (Verhoeven A.G.A. et al 2001 The ECRH system for JET 26th Int. Conf. on Infrared and Millimeter Waves (Toulouse, 10 14 September 2001) p 83; Verhoeven A.G.A. et al 2003 The 113 GHz ECRH system for JET Proc. 12th Joint Workshop on ECE and ECRH (13 16 May 2002) ed G. Giruzzi (Aix-en-Provence: World Scientific) pp 511 16). The main aim was to enable the control of neo-classical tearing modes. The paper will concentrate on: the power-supply and modulation system, including series IGBT switches, to enable independent control of each gyrotron and an all-solid-state body power supply to stabilize the gyrotron output power and to enable fast modulations up to 10 kHz and a plug-in launcher that is steerable in both toroidal and poloidal angles and able to handle eight separate mm-wave beams. Four steerable launching mirrors were foreseen to handle two mm-wave beams each. Water cooling of all the mirrors was a particularly ITER-relevant feature.

  18. Implications of Upwells as Hydrodynamic Jets in a Pulse Jet Mixed System

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pease, Leonard F.; Bamberger, Judith A.; Minette, Michael J.

    2015-08-01

    This report evaluates the physics of the upwell flow in pulse jet mixed systems in the Hanford Tank Waste Treatment and Immobilization Plant (WTP). Although the initial downward flow and radial flow from pulse jet mixers (PJMs) has been analyzed in some detail, the upwells have received considerably less attention despite having significant implications for vessel mixing. Do the upwells behave like jets? How do the upwells scale? When will the central upwell breakthrough? What proportion of the vessel is blended by the upwells themselves? Indeed, how the physics of the central upwell is affected by multiple PJMs (e.g., sixmore » in the proposed mixing vessels), non-Newtonian rheology, and significant multicomponent solids loadings remain unexplored. The central upwell must satisfy several criteria to be considered a free jet. First, it must travel for several diameters in a nearly constant direction. Second, its velocity must decay with the inverse of elevation. Third, it should have an approximately Gaussian profile. Fourth, the influence of surface or body forces must be negligible. A combination of historical data in a 12.75 ft test vessel, newly analyzed data from the 8 ft test vessel, and conservation of momentum arguments derived specifically for PJM operating conditions demonstrate that the central upwell satisfies these criteria where vigorous breakthrough is achieved. An essential feature of scaling from one vessel to the next is the requirement that the underlying physics does not change adversely. One may have confidence in scaling if (1) correlations and formulas capture the relevant physics; (2) the underlying physics does not change from the conditions under which it was developed to the conditions of interest; (3) all factors relevant to scaling have been incorporated, including flow, material, and geometric considerations; and (4) the uncertainty in the relationships is sufficiently narrow to meet required specifications. Although the central

  19. Lear jet telescope system

    NASA Technical Reports Server (NTRS)

    Erickson, E. F.; Goorvitch, D.; Dix, M. G.; Hitchman, M. J.

    1974-01-01

    The telescope system was designed as a multi-user facility for observations of celestial objects at infrared wavelengths, where ground-based observations are difficult or impossible due to the effects of telluric atmospheric absorption. The telescope is mounted in a Lear jet model 24B which typically permits 70 min. of observing per flight at altitudes in excess of 45,000 ft (13 km). Telescope system installation is discussed, along with appropriate setup and adjustment procedures. Operation of the guidance system is also explained, and checklists are provided which pertain to the recommended safe operating and in-flight trouble-shooting procedures for the equipment.

  20. The Chemistry of Protostellar Jet-Disk Systems

    NASA Astrophysics Data System (ADS)

    Codella, Claudio

    2017-11-01

    The birth of a Sun-like star is a complex game played by several participants whose respective roles are not yet entirely clear. On the one hand, the star-to-be accretes matter from a collapsing envelope. The gravitational energy released in the process heats up the material surrounding the protostar, creating warm regions enriched by interstellar complex organic molecules (iCOMs, at least 6 atoms) called hot-corinos. On the other hand, the presence of angular momentum and magnetic fields leads to two consequences: (i) the formation of circumstellar disks; and (ii) substantial episodes of matter ejection, as e.g. collimated jets. Thanks to the combination of the high-sensitivities and high-angular resolu- tions provided by the advent of new telescopes such as ALMA and NOEMA, it is now possible to image in details the earliest stages of the Sun-like star formation, thus inspecting the inner ( < 50 AU from the protostar) jet. at these spatial scales a proper study of jets has to take into account also the effects connected with the accreting disk. In other words, it is time to study the protostellar jet-disk system as a whole. Several still unanswered questions can be addressed. What is the origin of the chemically enriched hot corinos: are they jet-driven shocked regions? What is the origin of the ejections: are they due to disk or stellar winds? Shocks are precious tool to attack these questions, given they enrich the gas phase with the species deposited onto the dust mantles and/or locked in the refractory dust cores. Basically, we have to deal with two kind of shocks: (i) high-velocity shocks produced by protostellar jets, and (ii) slow accretion shocks located close to the centrifugal barrier of the accretion disks. Both shocks are factories of iCOMs, which can be then efficiently used to follow both the kinematics and the chemistry of the inner protostellar systems. With this in mind, we will discuss recent results obtained in the framework of different

  1. 21 CFR 876.4650 - Water jet renal stone dislodger system.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Water jet renal stone dislodger system. 876.4650 Section 876.4650 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GASTROENTEROLOGY-UROLOGY DEVICES Surgical Devices § 876.4650 Water jet renal stone dislodger system. (a) Identification....

  2. Succession of splicing regulatory elements determines cryptic 5΄ss functionality

    PubMed Central

    Brillen, Anna-Lena; Schöneweis, Katrin; Walotka, Lara; Hartmann, Linda; Müller, Lisa; Ptok, Johannes; Kaisers, Wolfgang; Poschmann, Gereon; Stühler, Kai; Buratti, Emanuele

    2017-01-01

    Abstract A critical step in exon definition is the recognition of a proper splice donor (5΄ss) by the 5’ end of U1 snRNA. In the selection of appropriate 5΄ss, cis-acting splicing regulatory elements (SREs) are indispensable. As a model for 5΄ss recognition, we investigated cryptic 5΄ss selection within the human fibrinogen Bβ-chain gene (FGB) exon 7, where we identified several exonic SREs that simultaneously acted on up- and downstream cryptic 5΄ss. In the FGB exon 7 model system, 5΄ss selection iteratively proceeded along an alternating sequence of U1 snRNA binding sites and interleaved SREs which in principle supported different 3’ exon ends. Like in a relay race, SREs either suppressed a potential 5΄ss and passed the splicing baton on or splicing actually occurred. From RNA-Seq data, we systematically selected 19 genes containing exons with silent U1 snRNA binding sites competing with nearby highly used 5΄ss. Extensive SRE analysis by different algorithms found authentic 5΄ss significantly more supported by SREs than silent U1 snRNA binding sites, indicating that our concept may permit generalization to a model for 5΄ss selection and 3’ exon end definition. PMID:28039323

  3. A cognitive robotics system: the symbolic and sub-symbolic robotic intelligence control system (SS-RICS)

    NASA Astrophysics Data System (ADS)

    Kelley, Troy D.; Avery, Eric

    2010-04-01

    This paper will detail the progress on the development of the Symbolic and Subsymbolic Robotics Intelligence Control System (SS-RICS). The system is a goal oriented production system, based loosely on the cognitive architecture, the Adaptive Control of Thought-Rational (ACT-R) some additions and changes. We have found that in order to simulate complex cognition on a robot, many aspects of cognition (long term memory (LTM), perception) needed to be in place before any generalized intelligent behavior can be produced. In working with ACT-R, we found that it was a good instantiation of working memory, but that we needed to add other aspects of cognition including LTM and perception to have a complete cognitive system. Our progress to date will be noted and the challenges that remain will be addressed.

  4. The JET diagnostic fast central acquisition and trigger system (abstract)

    NASA Astrophysics Data System (ADS)

    Edwards, A. W.; Blackler, K.

    1995-01-01

    Most plasma physics diagnostics sample at a fixed frequency that is normally matched to available memory limits. This technique is not appropriate for long pulse machines such as JET where sampling frequencies of hundreds of kHz are required to diagnose very fast events. As a result of work using real-time event selection within the previous JET soft x-ray diagnostic, a single data acquisition and event triggering system for all suitable fast diagnostics, the fast central acquisition and trigger system (Fast CATS), has been developed for JET. The front-end analog-to-digital conversion (ADC) part samples all channels at 250 kHz, with a 100 kHz pass band and a stop band of 125 kHz. The back-end data collection system is based around Texas Instruments TMS320C40 microprocessors. Within this system, two levels of trigger algorithms are able to evaluate data. The first level typically analyzes data on a per diagnostic and individual channel basis. The second level looks at the data from one or more diagnostics in a window around the time of interest flagged by the first level system. Selection criteria defined by the diagnosticians are then imposed on the results from the second level to decide whether that data should be kept. The use of such a system involving intelligent real time trigger algorithms and fast data analysis will improve both the quantity and quality of JET diagnostic data, while providing valuable input to the design of data acquisition systems for very long pulse machines such as ITER. This paper will give an overview of the various elements of this new system. In addition, first results from this system following the restart of JET operation will be presented.

  5. Characterization of systemic disease in primary Sjögren's syndrome: EULAR-SS Task Force recommendations for articular, cutaneous, pulmonary and renal involvements.

    PubMed

    Ramos-Casals, Manuel; Brito-Zerón, Pilar; Seror, Raphaèle; Bootsma, Hendrika; Bowman, Simon J; Dörner, Thomas; Gottenberg, Jacques-Eric; Mariette, Xavier; Theander, Elke; Bombardieri, Stefano; De Vita, Salvatore; Mandl, Thomas; Ng, Wan-Fai; Kruize, Aike; Tzioufas, Athanasios; Vitali, Claudio

    2015-12-01

    To reach a European consensus on the definition and characterization of the main organ-specific extraglandular manifestations in primary SS. The EULAR-SS Task Force Group steering committee agreed to approach SS-related systemic involvement according to the EULAR SS Disease Activity Index (ESSDAI) classification and proposed the preparation of four separate manuscripts: articular, cutaneous, pulmonary and renal ESSDAI involvement; muscular, peripheral nervous system, CNS and haematological ESSDAI involvement; organs not included in the ESSDAI classification; and lymphoproliferative disease. Currently available evidence was obtained by a systematic literature review focused on SS-related systemic features. The following information was summarized for articular, cutaneous, pulmonary and renal involvement: a clear, consensual definition of the clinical feature, a brief epidemiological description including an estimate of the prevalence reported in the main clinical series and a brief list of the key clinical and diagnostic features that could help physicians clearly identify these features. Unfortunately we found that the body of evidence relied predominantly on information retrieved from individual cases, and the scientific information provided was heterogeneous. The analysis of types of involvement was biased due to the unbalanced reporting of severe cases over non-severe cases, although the main sources of bias were the heterogeneous definitions of organ involvement (or even the lack of definition in some studies) and the heterogeneous diagnostic approach used in studies to investigate involvment of each organ. The proposals included in this article are a first step to developing an optimal diagnostic approach to systemic involvement in primary SS and may pave the way for further development of evidence-based diagnostic and therapeutic guidelines. © The Author 2015. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights

  6. Twin Jet

    NASA Technical Reports Server (NTRS)

    Henderson, Brenda; Bozak, Rick

    2010-01-01

    Many subsonic and supersonic vehicles in the current fleet have multiple engines mounted near one another. Some future vehicle concepts may use innovative propulsion systems such as distributed propulsion which will result in multiple jets mounted in close proximity. Engine configurations with multiple jets have the ability to exploit jet-by-jet shielding which may significantly reduce noise. Jet-by-jet shielding is the ability of one jet to shield noise that is emitted by another jet. The sensitivity of jet-by-jet shielding to jet spacing and simulated flight stream Mach number are not well understood. The current experiment investigates the impact of jet spacing, jet operating condition, and flight stream Mach number on the noise radiated from subsonic and supersonic twin jets.

  7. SS-mPMG and SS-GA: tools for finding pathways and dynamic simulation of metabolic networks.

    PubMed

    Katsuragi, Tetsuo; Ono, Naoaki; Yasumoto, Keiichi; Altaf-Ul-Amin, Md; Hirai, Masami Y; Sriyudthsak, Kansuporn; Sawada, Yuji; Yamashita, Yui; Chiba, Yukako; Onouchi, Hitoshi; Fujiwara, Toru; Naito, Satoshi; Shiraishi, Fumihide; Kanaya, Shigehiko

    2013-05-01

    Metabolomics analysis tools can provide quantitative information on the concentration of metabolites in an organism. In this paper, we propose the minimum pathway model generator tool for simulating the dynamics of metabolite concentrations (SS-mPMG) and a tool for parameter estimation by genetic algorithm (SS-GA). SS-mPMG can extract a subsystem of the metabolic network from the genome-scale pathway maps to reduce the complexity of the simulation model and automatically construct a dynamic simulator to evaluate the experimentally observed behavior of metabolites. Using this tool, we show that stochastic simulation can reproduce experimentally observed dynamics of amino acid biosynthesis in Arabidopsis thaliana. In this simulation, SS-mPMG extracts the metabolic network subsystem from published databases. The parameters needed for the simulation are determined using a genetic algorithm to fit the simulation results to the experimental data. We expect that SS-mPMG and SS-GA will help researchers to create relevant metabolic networks and carry out simulations of metabolic reactions derived from metabolomics data.

  8. Preliminary Study Using Forward Reaction Control System Jets During Space Shuttle Entry

    NASA Technical Reports Server (NTRS)

    Restrepo, Carolina; Valasek, John

    2006-01-01

    Failure or degradation of the flight control system, or hull damage, can lead to loss of vehicle control during entry. Possible failure scenarios are debris impact and wing damage that could result in a large aerodynamic asymmetry which cannot be trimmed out without additional yaw control. Currently the space shuttle uses aerodynamic control surfaces and Reaction Control System jets to control attitude. The forward jets are used for orbital maneuvering only, while the aft jets are used for yaw control during entry. This paper develops a controller for using the forward reaction control system jets as an additional control during entry, and assesses its value and feasibility during failure situations. Forward-aft jet blending logic is created, and implemented on a simplified model of the space shuttle entry flight control system. The model is validated and verified on the nonlinear, six degree-of-freedom Shuttle Engineering Simulator. A rudimentary human factors study was undertaken using the forward cockpit simulator at Johnson Space Center, to assess flying qualities of the new system and pilot workload. Results presented in the paper show that the combination of forward and aft jets provides useful additional yaw control, in addition to potential fuel savings and the ability to balance the use of the fuel in the forward and aft tanks to meet availability constraints of both forward and aft fuel tanks. Piloted simulation studies indicated that using both sets of jets while flying a damaged space shuttle reduces pilot workload, and makes the vehicle more responsive.

  9. Experimental measurement of stationary SS 304, SS 316L and 8630 GTA weld pool surface temperatures

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kraus, H.G.

    1989-07-01

    The optical spectral radiometric/laser reflectance experimental method, previously developed by the author, was extended to obtain high-resolution surface temperature maps of stationary GTA molten weld pools using thick-plate SS 304, SS316L, and 8630 steel. Increasing the welding current from 50 to 200 A resulted in peak pool surface temperatures from 1050{sup 0} to 2400{sup 0}C for the SS 304. At a constant welding current of 150 A, the SS 304 and various heats of SS 316L and 8630 resulted in peak weld pool temperatures from 2300{sup 0} to 2700{sup 0}C. Temperature contour plots of all the welds made are given.more » Surface temperature maps are classified into types that are believed to be indicative of the convective circulation patterns present in the weld pools.« less

  10. Identification of the Vibrio parahaemolyticus type III secretion system 2-associated chaperone VocC for the T3SS2-specific effector VopC.

    PubMed

    Akeda, Yukihiro; Kodama, Toshio; Saito, Kazunobu; Iida, Tetsuya; Oishi, Kazunori; Honda, Takeshi

    2011-11-01

    The enteropathogen Vibrio parahaemolyticus possesses two sets of type III secretion systems, T3SS1 and T3SS2. Effector proteins secreted by these T3SSs are delivered into host cells, leading to cell death or diarrhea. However, it is not known how specific effectors are secreted through a specific T3SS when both T3SSs are expressed within bacteria. One molecule thought to determine secretion specificity is a T3SS-associated chaperone; however, no T3SS2-specific chaperone has been identified. Therefore, we screened T3SS2 chaperone candidates by a pull-down assay using T3SS2 effectors fused with glutathione-S-transferase. A secretion assay revealed that the newly identified cognate chaperone VocC for the T3SS2-specific effector VopC was required for the efficient secretion of the substrate through T3SS2. Further experiments determined the chaperone-binding domain and the amino-terminal secretion signal of the cognate effector. These findings, in addition to the previously identified T3SS1-specific chaperone, VecA, provide a strategy to clarify the specificity of effector secretion through T3SSs of V. parahaemolyticus. 2011 Federation of European Microbiological Societies. Published by Blackwell Publishing Ltd. All rights reserved.

  11. Corkscrew Structures and Precessing Jets

    NASA Astrophysics Data System (ADS)

    Sahai, Raghvendra

    2005-07-01

    Collimated jets are one of the most intriguing, yet poorly understood phenomena in astrophysics. Jets have been found in a wide variety of object classes which include AGNs, YSOs, massive X-ray binaries {e.g. SS433}, black hole X-ray transients, symbiotic stars, supersoft X-ray sources, and finally, planetary and preplanetary nebulae {PNs & PPNs}. In the case of PNs and PPNs, we have propsoed that wobbling collimated jets are the universal mechanism which can shape the wide variety of bipolar and multipolar morphologies seen in these objects. Most of our knowledge of post-AGB jets is indirectly inferred from their effects on the circumstellar envelopes of the progenitor AGB stars and, for that reason, these jets remain very poorly understood. Thus the mechanism that powers and collimates these jet-like post-AGB outflows remains as one of the most important, unsolved issues in post-AGB evolution. We propose an archival study of two bipolar PPNs, motivated by two recent discoveries which indicate that precessing jets are likely to be operational in them, and that the properties of the jets and the bipolar lobes produced by them, may be directly measured. One of these is IRAS16342-3814 {IRAS1634}, previously imaged with WPFC2, in which new Adaptive Optics {AO} observations at near-IR wavelengths show a remarkable corkscrew-shaped structure, the tell-tale signature of a precessing jet. Inspection of WFPC2 images of another PPN, OH231.8+4.2 in which we have recently discovered a A-type companion to the central mass-losing star, shows a sinuous nebulosity in a broad-band continuum image, resembling a corkscrew structure. We will use the latter to constrain the phsyical properties of the jet {precession period, opening angle, jet beam diameter, temporal history} in OH231.8. Using the multi-wavelength data on both sources, we will build models of the density distribution of the lobes and their interiors. In the case of IRAS1634, these models will be used to investigate the

  12. Hydrodynamic Stability Analysis of Multi-jet Effects in Swirling Jet Combustors

    NASA Astrophysics Data System (ADS)

    Emerson, Benjamin; Lieuwen, Tim

    2016-11-01

    Many practical combustion devices use multiple swirling jets to stabilize flames. However, much of the understanding of swirling jet dynamics has been generated from experimental and computational studies of single reacting, swirling jets. A smaller body of literature has begun to explore the effects of multi-jet systems and the role of jet-jet interactions on the macro-system dynamics. This work uses local temporal and spatio-temporal stability analyses to isolate the hydrodynamic interactions of multiple reacting, swirling jets, characterized by jet diameter, D, and spacing, L. The results first identify the familiar helical modes in the single jet. Comparison to the multi-jet configuration reveals these same familiar modes simultaneously oscillating in each of the jets. Jet-jet interaction is mostly limited to a spatial synchronization of each jet's oscillations at the jet spacing values analyzed here (L/D =3.5). The presence of multiple jets vs a single jet has little influence on the temporal and absolute growth rates. The biggest difference between the single and multi-jet configurations is the presence of nearly degenerate pairs of hydrodynamic modes in the multi-jet case, with one mode dominated by oscillations in the inner jet, and the other in the outer jets. The close similarity between the single and multi-jet hydrodynamics lends insight into experiments from our group.

  13. Validation of Robotic Surgery Simulator (RoSS).

    PubMed

    Kesavadas, Thenkurussi; Stegemann, Andrew; Sathyaseelan, Gughan; Chowriappa, Ashirwad; Srimathveeravalli, Govindarajan; Seixas-Mikelus, Stéfanie; Chandrasekhar, Rameella; Wilding, Gregory; Guru, Khurshid

    2011-01-01

    Recent growth of daVinci Robotic Surgical System as a minimally invasive surgery tool has led to a call for better training of future surgeons. In this paper, a new virtual reality simulator, called RoSS is presented. Initial results from two studies - face and content validity, are very encouraging. 90% of the cohort of expert robotic surgeons felt that the simulator was excellent or somewhat close to the touch and feel of the daVinci console. Content validity of the simulator received 90% approval in some cases. These studies demonstrate that RoSS has the potential of becoming an important training tool for the daVinci surgical robot.

  14. Unsteady jet in designing innovative drug delivery system

    NASA Astrophysics Data System (ADS)

    Wang, Cong; Mazur, Paul; Cosse, Julia; Rider, Stephanie; Gharib, Morteza

    2014-11-01

    Micro-needle injections, a promising pain-free drug delivery method, is constrained by its limited penetration depth. This deficiency can be overcome by implementing fast unsteady jet that can penetrate sub-dermally. The development of a faster liquid jet would increase the penetration depth and delivery volume of micro-needles. In this preliminary work, the nonlinear transient behavior of an elastic tube balloon in providing fast discharge is analyzed. A physical model that combines the Mooney Rivlin Material model and Young-Lapalce's Law was developed and used to investigate the fast discharging dynamic phenomenon. A proof of concept prototype was constructed to demonstrate the feasibility of a simple thumb-sized delivery system to generate liquid jet with desired speed in the range of 5-10 m/s. This work is supported by ZCUBE Corporation.

  15. Rewetting of hot vertical rod during jet impingement surface cooling

    NASA Astrophysics Data System (ADS)

    Agrawal, Chitranjan; Kumar, Ravi; Gupta, Akhilesh; Chatterjee, Barun

    2016-06-01

    A stainless steel (SS-316) vertical rod of 12 mm diameter at 800 ± 10 °C initial temperature was cooled by normal impinging round water jet. The surface rewetting phenomenon was investigated for a range of jet diameter 2.5-4.8 mm and jet Reynolds number 5000-24,000 using a straight tube type nozzle. The investigation were made from the stagnation point to maximum 40 mm downstream locations, simultaneously for both upside and downside directions. The cooling performance of the vertical rod was evaluated on the basis of rewetting parameters i.e. rewetting temperature, wetting delay, rewetting velocity and the maximum surface heat flux. Two separate Correlations have been proposed for the dimensionless rewetting velocity in terms of rewetting number and the maximum surface heat flux that predicts the experimental data within an error band of ±20 and ±15 % respectively.

  16. Jet plume injection and combustion system for internal combustion engines

    DOEpatents

    Oppenheim, A.K.; Maxson, J.A.; Hensinger, D.M.

    1993-12-21

    An improved combustion system for an internal combustion engine is disclosed wherein a rich air/fuel mixture is furnished at high pressure to one or more jet plume generator cavities adjacent to a cylinder and then injected through one or more orifices from the cavities into the head space of the cylinder to form one or more turbulent jet plumes in the head space of the cylinder prior to ignition of the rich air/fuel mixture in the cavity of the jet plume generator. The portion of the rich air/fuel mixture remaining in the cavity of the generator is then ignited to provide a secondary jet, comprising incomplete combustion products which are injected into the cylinder to initiate combustion in the already formed turbulent jet plume. Formation of the turbulent jet plume in the head space of the cylinder prior to ignition has been found to yield a higher maximum combustion pressure in the cylinder, as well as shortening the time period to attain such a maximum pressure. 24 figures.

  17. Jet plume injection and combustion system for internal combustion engines

    DOEpatents

    Oppenheim, Antoni K.; Maxson, James A.; Hensinger, David M.

    1993-01-01

    An improved combustion system for an internal combustion engine is disclosed wherein a rich air/fuel mixture is furnished at high pressure to one or more jet plume generator cavities adjacent to a cylinder and then injected through one or more orifices from the cavities into the head space of the cylinder to form one or more turbulent jet plumes in the head space of the cylinder prior to ignition of the rich air/fuel mixture in the cavity of the jet plume generator. The portion of the rich air/fuel mixture remaining in the cavity of the generator is then ignited to provide a secondary jet, comprising incomplete combustion products which are injected into the cylinder to initiate combustion in the already formed turbulent jet plume. Formation of the turbulent jet plume in the head space of the cylinder prior to ignition has been found to yield a higher maximum combustion pressure in the cylinder, as well as shortening the time period to attain such a maximum pressure.

  18. Active control of continuous air jet with bifurcated synthetic jets

    NASA Astrophysics Data System (ADS)

    Dančová, Petra; Vít, Tomáš; Jašíková, Darina; Novosád, Jan

    The synthetic jets (SJs) have many significant applications and the number of applications is increasing all the time. In this research the main focus is on the primary flow control which can be used effectively for the heat transfer increasing. This paper deals with the experimental research of the effect of two SJs worked in the bifurcated mode used for control of an axisymmetric air jet. First, the control synthetic jets were measured alone. After an adjustment, the primary axisymmetric jet was added in to the system. For comparison, the primary flow without synthetic jets control was also measured. All experiments were performed using PIV method whereby the synchronization between synthetic jets and PIV system was necessary to do.

  19. Serotoninergic neuronal systems and ethanol sensitivity in long-sleep (LS) and short-sleep (SS) mice

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    French, T.A.; Weiner, N.

    LS and SS mice selectively bred for differences in CNS sensitivity to ethanol (EtOH) exhibit markedly different sleep times (LS = 120 min; SS = 13 min) and differ considerably in hypothermic response following EtOH< 4 g/kg i.p. Basal levels of serotonin (5HT), 5-hydroxyindole acetic acid and 5HT turnover (defined as 5-hydroxy-tryptophan accumulation after inhibition of aromatic L-amino acid decarboxylase) in 6 brain regions (hypthalamus (HYP), dorsal raphe (DR), pontine-medullary raphe (PMR), striatum (STR), hippocampus (HIP) and cortex (CTX)) differ minimally between the two lines. 5 HT turnover in STR, HIP, CTX and PMR of either LS or SS micemore » or in HYP or DR of SS mice was not altered at either 20 or 120 min after EtOH, 4 g/kg. However, in LS mice, 5HT turnover was decreased 23% in HYP at 20 min and 30-34% in HYP and DR at 120 min. LS mice become 1.2 and 2.2/sup 0/ more hypothermic than SS mice at 20 and 120 min after EtOH, 4 g/kg. When approximately equi-effective hypothermic doses of EtOH were administered to LS (3.5 g/kg) and SS (5.0 g/kg) mice, differences in 5HT turnover were still apparent. Pentobarbital administration (65 mg/kg) both decreased brain 5HT turnover 30-60% and produced comparable degrees of hypothermia in LS and SS mice. These data suggest that the apparent increase in sensitivity to inhibition by EtOH of 5HT neurons of HYP and DR of LS mice may contribute to the greater degree of hypothermia induced in this line.« less

  20. Chitin-induced T6SS in Vibrio cholerae is dependent on ChiS activation.

    PubMed

    Chourashi, Rhishita; Das, Suman; Dhar, Debarpan; Okamoto, Keinosuke; Mukhopadhyay, Asish K; Chatterjee, Nabendu Sekhar

    2018-05-01

    Vibrio cholerae regularly colonizes the chitinous exoskeleton of crustacean shells in the aquatic region. The type 6 secretion system (T6SS) in V. cholerae is an interbacterial killing device. This system is thought to provide a competitive advantage to V. cholerae in a polymicrobial community of the aquatic region under nutrient-poor conditions. V. cholerae chitin sensing is known to be initiated by the activation of a two-component sensor histidine kinase ChiS in the presence of GlcNAc2 (N,N'-diacetylchitobiose) residues generated by the action of chitinases on chitin. It is known that T6SS in V. cholerae is generally induced by chitin. However, the effect of ChiS activation on T6SS is unknown. Here, we found that ChiS inactivation resulted in impaired bacterial killing and reduced expression of T6SS genes. Active ChiS positively affected T6SS-mediated natural transformation in V. cholerae. ChiS depletion or inactivation also resulted in reduced colonization on insoluble chitin surfaces. Therefore, we have shown that V. cholerae colonization on chitinous surfaces activates ChiS, which promotes T6SS-dependent bacterial killing and horizontal gene transfer. We also highlight the importance of chitinases in T6SS upregulation.

  1. New jet-aeration system using 'Supercavitation'.

    PubMed

    Schmid, Andreas

    2010-03-01

    A newly developed fine bubble aeration system, by which air is transferred under supercavitation conditions, shows a clearly better performance than traditional, well-known aerators that rely on the jet-pump principle and its performance can be compared to oxygen transfer rates achieved in membrane and foil plate aerators. A prototype supercavitation aerator installed at a sewage treatment plant revealed an air input rate, which was about one third lower than that of the jet-pump system, which it replaced. In spite of this low air input rate, the daily demand of pure oxygen for the additionally installed membrane aeration system went down by approximately 49%, from the original level of about 1,200 m(3)/day to about 600 m(3)/day-and this over a test period of more than 7 months. The observed high oxygen transfer rates cannot be explained by traditional mass transfer mechanisms. It is assumed that a large amount of water being transferred into the gas phase by supercavitation contacting directly oxygen also in the gas phase and thereby overcoming mass transfer hindrances which might be favoured by hydroxyl radicals. With this new aerator, during the first 3 months of test phase, already more than 10,000 Euros had been saved because of the reduced pure oxygen demand.

  2. Battery-Powered RF Pre-Ionization System for the Caltech Magnetohydrodynamically-Driven Jet Experiment: RF Discharge Properties and MHD-Driven Jet Dynamics

    NASA Astrophysics Data System (ADS)

    Chaplin, Vernon H.

    This thesis describes investigations of two classes of laboratory plasmas with rather different properties: partially ionized low pressure radiofrequency (RF) discharges, and fully ionized high density magnetohydrodynamically (MHD)-driven jets. An RF pre-ionization system was developed to enable neutral gas breakdown at lower pressures and create hotter, faster jets in the Caltech MHD-Driven Jet Experiment. The RF plasma source used a custom pulsed 3 kW 13.56 MHz RF power amplifier that was powered by AA batteries, allowing it to safely float at 4-6 kV with the cathode of the jet experiment. The argon RF discharge equilibrium and transport properties were analyzed, and novel jet dynamics were observed. Although the RF plasma source was conceived as a wave-heated helicon source, scaling measurements and numerical modeling showed that inductive coupling was the dominant energy input mechanism. A one-dimensional time-dependent fluid model was developed to quantitatively explain the expansion of the pre-ionized plasma into the jet experiment chamber. The plasma transitioned from an ionizing phase with depressed neutral emission to a recombining phase with enhanced emission during the course of the experiment, causing fast camera images to be a poor indicator of the density distribution. Under certain conditions, the total visible and infrared brightness and the downstream ion density both increased after the RF power was turned off. The time-dependent emission patterns were used for an indirect measurement of the neutral gas pressure. The low-mass jets formed with the aid of the pre-ionization system were extremely narrow and collimated near the electrodes, with peak density exceeding that of jets created without pre-ionization. The initial neutral gas distribution prior to plasma breakdown was found to be critical in determining the ultimate jet structure. The visible radius of the dense central jet column was several times narrower than the axial current channel

  3. Water Jetting

    NASA Technical Reports Server (NTRS)

    1985-01-01

    Hi-Tech Inc., a company which manufactures water jetting equipment, needed a high pressure rotating swivel, but found that available hardware for the system was unsatisfactory. They were assisted by Marshall, which had developed water jetting technology to clean the Space Shuttles. The result was a completely automatic water jetting system which cuts rock and granite and removes concrete. Labor costs have been reduced; dust is suppressed and production has been increased.

  4. Type 3 Secretion System (T3SS) of Bradyrhizobium sp. DOA9 and Its Roles in Legume Symbiosis and Rice Endophytic Association.

    PubMed

    Songwattana, Pongpan; Noisangiam, Rujirek; Teamtisong, Kamonluck; Prakamhang, Janpen; Teulet, Albin; Tittabutr, Panlada; Piromyou, Pongdet; Boonkerd, Nantakorn; Giraud, Eric; Teaumroong, Neung

    2017-01-01

    The Bradyrhizobium sp. DOA9 strain isolated from a paddy field has the ability to nodulate a wide spectrum of legumes. Unlike other bradyrhizobia, this strain has a symbiotic plasmid harboring nod , nif , and type 3 secretion system (T3SS) genes. This T3SS cluster contains all the genes necessary for the formation of the secretory apparatus and the transcriptional activator (TtsI), which is preceded by a nod -box motif. An in silico search predicted 14 effectors putatively translocated by this T3SS machinery. In this study, we explored the role of the T3SS in the symbiotic performance of DOA9 by evaluating the ability of a T3SS mutant (Ω rhcN ) to nodulate legumes belonging to Dalbergioid, Millettioid, and Genistoid tribes. Among the nine species tested, four ( Arachis hypogea , Vigna radiata , Crotalaria juncea , and Macroptilium atropurpureum ) responded positively to the rhcN mutation (ranging from suppression of plant defense reactions, an increase in the number of nodules and a dramatic improvement in nodule development and infection), one ( Stylosanthes hamata ) responded negatively (fewer nodules and less nitrogen fixation) and four species ( Aeschynomene americana , Aeschynomene afraspera , Indigofera tinctoria , and Desmodium tortuosum ) displayed no phenotype. We also tested the role of the T3SS in the ability of the DOA9 strain to endophytically colonize rice roots, but detected no effect of the T3SS mutation, in contrast to what was previously reported in the Bradyrhizobium SUTN9-2 strain. Taken together, these data indicate that DOA9 contains a functional T3SS that interferes with the ability of the strain to interact symbiotically with legumes but not with rice.

  5. PLIF Study of Mars Science Laboratory Capsule Reaction Control System Jets

    NASA Technical Reports Server (NTRS)

    Johansen, C. T.; Danehy, P. M.; Ashcraft, S. W.; Bathel, B. F.; Inman, J. A.; Jones, S. B.

    2011-01-01

    Nitric-oxide planar laser-induced fluorescence (NO PLIF) was used to visualize the flow in the wake of a Mars Science Lab (MSL) entry capsule with activated reaction control system (RCS) jets in NASA Langley Research Center s 31-Inch Mach 10 Air Tunnel facility. Images were processed using the Virtual Diagnostics Interface (ViDI) method, which brings out the three-dimensional nature of the flow visualization data while showing the relative location of the data with respect to the model. Comparison of wind-on and wind-off results illustrates the effect that the hypersonic crossflow has on the trajectory and structure of individual RCS jets. The visualization and comparison of both single and multiple activated RCS jets indicate low levels of jet-jet interaction. Quantitative streamwise velocity was also obtained via NO PLIF molecular tagging velocimetry (MTV).

  6. PLIF Study of Mars Science Laboratory Capsule Reaction Control System Jets

    NASA Technical Reports Server (NTRS)

    Johansen, C. T.; Danehy, P. M.; Ashcraft, S. W.; Bathel, B. F.; Inman, J. A.; Jones, S. B.

    2011-01-01

    Nitric-oxide planar laser-induced fluorescence (NO PLIF) was used to visualize the flow in the wake of a Mars Science Lab (MSL) entry capsule with activated reaction control system (RCS) jets in NASA Langley Research Center's 31-Inch Mach 10 Air Tunnel facility. Images were processed using the Virtual Diagnostics Interface (ViDI) method, which brings out the three-dimensional nature of the flow visualization data while showing the relative location of the data with respect to the model. Comparison of wind-on and wind-off results illustrates the effect that the hypersonic crossflow has on the trajectory and structure of individual RCS jets. The visualization and comparison of both single and multiple activated RCS jets indicate low levels of jet-jet interaction. Quantitative streamwise velocity was also obtained via NO PLIF molecular tagging velocimetry (MTV).

  7. Evolutionarily Conserved nodE, nodO, T1SS, and Hydrogenase System in Rhizobia of Astragalus membranaceus and Caragana intermedia.

    PubMed

    Yan, Hui; Xie, Jian Bo; Ji, Zhao Jun; Yuan, Na; Tian, Chang Fu; Ji, Shou Kun; Wu, Zhong Yu; Zhong, Liang; Chen, Wen Xin; Du, Zheng Lin; Wang, En Tao; Chen, Wen Feng

    2017-01-01

    Mesorhizobium species are the main microsymbionts associated with the medicinal or sand-fixation plants Astragalus membranaceus and Caragana intermedia (AC) in temperate regions of China, while all the Mesorhizobium strains isolated from each of these plants could nodulate both of them. However, Rhizobium yanglingense strain CCBAU01603 could nodulate AC plants and it's a high efficiency symbiotic and competitive strain with Caragana . Therefore, the common features shared by these symbiotic rhizobia in genera of Mesorhizobium and Rhizobium still remained undiscovered. In order to study the genomic background influencing the host preference of these AC symbiotic strains, the whole genomes of two ( M. silamurunense CCBAU01550, M. silamurunense CCBAU45272) and five representative strains ( M. septentrionale CCBAU01583, M. amorphae CCBAU01570, M. caraganae CCBAU01502, M. temperatum CCBAU01399, and R. yanglingense CCBAU01603) originally isolated from AC plants were sequenced, respectively. As results, type III secretion systems (T3SS) of AC rhizobia evolved in an irregular pattern, while an evolutionarily specific region including nodE, nodO , T1SS, and a hydrogenase system was detected to be conserved in all these AC rhizobia. Moreover, nodO was verified to be prevalently distributed in other AC rhizobia and was presumed as a factor affecting the nodule formation process. In conclusion, this research interpreted the multifactorial features of the AC rhizobia that may be associated with their host specificity at cross-nodulation group, including nodE, nodZ , T1SS as the possible main determinants; and nodO , hydrogenase system, and T3SS as factors regulating the bacteroid formation or nitrogen fixation efficiency.

  8. Mechanochemical regulations of RPA's binding to ssDNA

    NASA Astrophysics Data System (ADS)

    Chen, Jin; Le, Shimin; Basu, Anindita; Chazin, Walter J.; Yan, Jie

    2015-03-01

    Replication protein A (RPA) is a ubiquitous eukaryotic single-stranded DNA (ssDNA) binding protein that serves to protect ssDNA from degradation and annealing, and as a template for recruitment of many downstream factors in virtually all DNA transactions in cell. During many of these transactions, DNA is tethered and is likely subject to force. Previous studies of RPA's binding behavior on ssDNA were conducted in the absence of force; therefore the RPA-ssDNA conformations regulated by force remain unclear. Here, using a combination of atomic force microscopy imaging and mechanical manipulation of single ssDNA tethers, we show that force mediates a switch of the RPA bound ssDNA from amorphous aggregation to a much more regular extended conformation. Further, we found an interesting non-monotonic dependence of the binding affinity on monovalent salt concentration in the presence of force. In addition, we discovered that zinc in micromolar concentrations drives ssDNA to a unique, highly stiff and more compact state. These results provide new mechanochemical insights into the influences and the mechanisms of action of RPA on large single ssDNA.

  9. Type 3 Secretion System (T3SS) of Bradyrhizobium sp. DOA9 and Its Roles in Legume Symbiosis and Rice Endophytic Association

    PubMed Central

    Songwattana, Pongpan; Noisangiam, Rujirek; Teamtisong, Kamonluck; Prakamhang, Janpen; Teulet, Albin; Tittabutr, Panlada; Piromyou, Pongdet; Boonkerd, Nantakorn; Giraud, Eric; Teaumroong, Neung

    2017-01-01

    The Bradyrhizobium sp. DOA9 strain isolated from a paddy field has the ability to nodulate a wide spectrum of legumes. Unlike other bradyrhizobia, this strain has a symbiotic plasmid harboring nod, nif, and type 3 secretion system (T3SS) genes. This T3SS cluster contains all the genes necessary for the formation of the secretory apparatus and the transcriptional activator (TtsI), which is preceded by a nod-box motif. An in silico search predicted 14 effectors putatively translocated by this T3SS machinery. In this study, we explored the role of the T3SS in the symbiotic performance of DOA9 by evaluating the ability of a T3SS mutant (ΩrhcN) to nodulate legumes belonging to Dalbergioid, Millettioid, and Genistoid tribes. Among the nine species tested, four (Arachis hypogea, Vigna radiata, Crotalaria juncea, and Macroptilium atropurpureum) responded positively to the rhcN mutation (ranging from suppression of plant defense reactions, an increase in the number of nodules and a dramatic improvement in nodule development and infection), one (Stylosanthes hamata) responded negatively (fewer nodules and less nitrogen fixation) and four species (Aeschynomene americana, Aeschynomene afraspera, Indigofera tinctoria, and Desmodium tortuosum) displayed no phenotype. We also tested the role of the T3SS in the ability of the DOA9 strain to endophytically colonize rice roots, but detected no effect of the T3SS mutation, in contrast to what was previously reported in the Bradyrhizobium SUTN9-2 strain. Taken together, these data indicate that DOA9 contains a functional T3SS that interferes with the ability of the strain to interact symbiotically with legumes but not with rice. PMID:28979252

  10. Consolidated Laser-Induced Fluorescence Diagnostic Systems for the NASA Ames Arc Jet Facilities

    NASA Technical Reports Server (NTRS)

    Grinstead, Jay H.; Wilder, Michael C.; Porter, Barry J.; Brown, Jeffrey D.; Yeung, Dickson; Battazzo, Stephen J.; Brubaker, Timothy R.

    2016-01-01

    The spectroscopic diagnostic technique of two photon absorption laser-induced fluorescence (TALIF) of atomic species for non-intrusive arc jet flow property measurement was first implemented at NASA Ames in the mid-1990s. Use of TALIF expanded at NASA Ames and to NASA Johnson's arc jet facility in the late 2000s. In 2013-2014, NASA combined the agency's large-scale arc jet test capabilities at NASA Ames. Concurrent with that effort, the agency also sponsored a project to establish two comprehensive LIF diagnostic systems for the Aerodynamic Heating Facility (AHF) and Interaction Heating Facility (IHF) arc jets. The scope of the project enabled further engineering development of the existing IHF LIF system as well as the complete reconstruction of the original AHF LIF system. The updated LIF systems are identical in design and capability. They represent the culmination of over 20 years of development experience in transitioning a specialized laboratory research tool into a measurement system for large-scale, high-demand test facilities. This paper documents the overall system design from measurement requirements to implementation. Representative data from the redeveloped AHF and IHF LIF systems are also presented.

  11. Consolidated Laser-Induced Fluorescence Diagnostic Systems for the NASA Ames Arc Jet Facilities

    NASA Technical Reports Server (NTRS)

    Grinstead, Jay; Wilder, Michael C.; Porter, Barry; Brown, Jeff; Yeung, Dickson; Battazzo, Steve; Brubaker, Tim

    2016-01-01

    The spectroscopic diagnostic technique of two photon absorption laser-induced fluorescence (TALIF) of atomic species for non-intrusive arc jet flow property measurement was first implemented at NASA Ames in the mid-1990s. Use of TALIF expanded at NASA Ames and to NASA Johnsons arc jet facility in the late 2000s. In 2013-2014, NASA combined the agency's large-scale arc jet test capabilities at NASA Ames. Concurrent with that effort, the agency also sponsored a project to establish two comprehensive LIF diagnostic systems for the Aerodynamic Heating Facility (AHF) and Interaction Heating Facility (IHF) arc jets. The scope of the project enabled further engineering development of the existing IHF LIF system as well as the complete reconstruction of the original AHF LIF system. The updated LIF systems are identical in design and capability. They represent the culmination of over 20 years of development experience in transitioning a specialized laboratory research tool into a measurement system for large-scale, high-demand test facilities. This paper documents the overall system design from measurement requirements to implementation. Representative data from the redeveloped AHF and IHF LIF systems are also presented.

  12. NASA Jet Noise Research

    NASA Technical Reports Server (NTRS)

    Henderson, Brenda

    2016-01-01

    The presentation highlights NASA's jet noise research for 2016. Jet-noise modeling efforts, jet-surface interactions results, acoustic characteristics of multi-stream jets, and N+2 Supersonic Aircraft system studies are presented.

  13. INFRARED SPECTROSCOPY OF SYMBIOTIC STARS. X. ORBITS FOR THREE S-TYPE SYSTEMS: V1044 CENTAURI, HEN 3-1213, AND SS 73-96

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fekel, Francis C.; Hinkle, Kenneth H.; Joyce, Richard R.

    Employing new infrared radial velocities, we have computed orbits of the cool giants in three southern S-type symbiotic systems. The orbit for V1044 Cen, an M5.5 giant, has a period of 985 days and a modest eccentricity of 0.16. Hen 3-1213 is a K4 giant, yellow symbiotic with an orbital period of 533 days and a similar eccentricity of 0.18. For the M2 giant SS 73-96 the orbital period is 828 days, and this system has a somewhat larger eccentricity of 0.26. Measurement of the H i Paschen δ emission lines, which may at least partially reflect the motion ofmore » the secondary in SS 73-96, results in a mass ratio of 2.4 for the M giant relative to the presumed white dwarf. The estimated orbital inclinations of V1044 Cen and Hen 3-1213 are low, about 40°. However, for SS 73-96 the predicted inclination is 90°, and so an ephemeris for eclipses of the secondary or the hot nebula surrounding it is provided. A search of the orbital velocity residuals of V1044 Cen and SS 73-96 for pulsation periods produced no realistic or convincing period for either star.« less

  14. Methods and system for subsurface stabilization using jet grouting

    DOEpatents

    Loomis, Guy G.; Weidner, Jerry R.; Farnsworth, Richard K.; Gardner, Bradley M.; Jessmore, James J.

    1999-01-01

    Methods and systems are provided for stabilizing a subsurface area such as a buried waste pit for either long term storage, or interim storage and retrieval. A plurality of holes are drilled into the subsurface area with a high pressure drilling system provided with a drill stem having jet grouting nozzles. A grouting material is injected at high pressure through the jet grouting nozzles into a formed hole while the drill stem is withdrawn from the hole at a predetermined rate of rotation and translation. A grout-filled column is thereby formed with minimal grout returns, which when overlapped with other adjacent grout-filled columns encapsulates and binds the entire waste pit area to form a subsurface agglomeration or monolith of grout, soil, and waste. The formed monolith stabilizes the buried waste site against subsidence while simultaneously providing a barrier against contaminate migration. The stabilized monolith can be left permanently in place or can be retrieved if desired by using appropriate excavation equipment. The jet grouting technique can also be utilized in a pretreatment approach prior to in situ vitrification of a buried waste site. The waste encapsulation methods and systems are applicable to buried waste materials such as mixed waste, hazardous waste, or radioactive waste.

  15. Multiwavelength Study of Powerful New Jet Activity in the Symbiotic Binary System R Aqr

    NASA Astrophysics Data System (ADS)

    Karovska, Margarita

    2016-09-01

    We propose to carry out coordinated high-spatial resolution Chandra ACIS-S and HST/WFC3 observations of R Aqr, a very active symbiotic interacting binary system. Our main goal is to study the physical characteristics of multi-scale components of the powerful jet; from near the central binary (within a few AU) to the jet-circumbinary material interaction region (2500 AU) and beyond , and especially of the recently discovered inner jet, to gain insight on early jet formation and propagation, such as jet kinematics and precession.

  16. Fluidized Bed Opposed Jet Mill System for Processing Inorganic Materials

    NASA Astrophysics Data System (ADS)

    Al-Nuzal, S. M. D.; Mohammed, M. I.

    2017-08-01

    A jet mill system was built aiming to give values for processing inorganic materials, to be used for different industry. The milling housing of the system is composed of; milling chamber, compressed air nozzles which deliver compressed air in the milling chamber to accelerate sample particles. The classifier wheel is composed of two concentric pieces welded together under argon and coupled to a AC Motor, 0 - 9000 rpm, 2 kW, with AC frequencies convertor. The performances of this jet mill system were tried on five cheap locally available materials, viz. white sand, glass, iron oxide, black carbon and alum. It is possible to get particle sizes of less than 1 μm with narrow distribution of particle sizes.

  17. Multiwavelength Study of Powerful New Jet Activity in the Symbiotic System R AQR

    NASA Astrophysics Data System (ADS)

    Karovska, Margarita

    2016-10-01

    We propose to carry out coordinated high-spatial resolution Chandra ACIS-S and multiwavelength (UV-Optical) HST/WFC3 observations of R Aqr, a very active symbiotic interacting binary system. Our main goal is to study the physical characteristics of the multi-scale components of the powerful jet; from the vicinity of the central binary (within a few AU) to the jet-circumbinary material interaction region (2500 AU) and beyond, and especially of the recently discovered new component of the inner jet (likely due to recent ejection of material). Our main goal is to gain new insight on early jet formation and propagation, including jet kinematics and precession.

  18. Exhaust turbine and jet propulsion systems

    NASA Technical Reports Server (NTRS)

    Leist, Karl; Knornschild, Eugen

    1951-01-01

    DVL experimental and analytical work on the cooling of turbine blades by using ram air as the working fluid over a sector or sectors of the turbine annulus area is summarized. The subsonic performance of ram-jet, turbo-jet, and turbine-propeller engines with both constant pressure and pulsating-flow combustion is investigated. Comparison is made with the performance of a reciprocating engine and the advantages of the gas turbine and jet-propulsion engines are analyzed. Nacelle installation methods and power-level control are discussed.

  19. SWIFT Observations of a Far UV Luminosity Component in SS433

    NASA Technical Reports Server (NTRS)

    Cannizzo, J. K.; Boyd, P. T.; Dolan, J. F.

    2007-01-01

    SS433 is a binary system showing relativistic Doppler shifts in its two sets of emission lines. The origin of its UV continuum is not well established. We observed SS433 to determine the emission mechanism responsible for its far UV spectrum. The source was observed at several different phases of both its 13 d orbital period and 162.5 d precession period using the UVOT and XRT detector systems on Swift. The far UV spectrum down to 1880 Angstrom lies significantly above the spectral flux distribution predicted by extrapolating the reddened blackbody continuum that fits the spectrum above 3500 Angstroms. The intensity of the far UV flux varies over a period of days and the variability is correlated with the variability of the soft X-ray flux from the source. An emission mechanism in addition to those previously detected in the optical and X-ray regions must exist in the far UV spectrum of SS433.

  20. Electrochemical studies on the performance of SS316L electrode in electrokinetics

    NASA Astrophysics Data System (ADS)

    Choi, Jeong-Hee; Maruthamuthu, Sundaram; Lee, Hyun-Goo; Ha, Tae-Hyun; Bae, Jeong-Hyo

    2009-10-01

    Organic and trace metal pollutants are removed by employing various electrodes in an electrokinetic (EK) process. Stainless steel was used either as an anode or a cathode by various investigators in electroremediation systems. In the present study, the role of SS316L as an anode and cathode in EK system was studied by the measurements of pH, conductivity of electrolyte, and potential of the anode and cathode at different current densities. The weight loss of the anode and cathode and the leaching of chromium, iron, and nickel at different current densities were measured and discussed with an electroosmosis process. The electrochemical behavior of SS316L electrode in neutral, acidic and alkaline pH in soil environment was studied by an electrochemical technique viz. polarization study. Surface analysis of SS316L after EK was done by XPS and SEM. The higher conductivity was noticed at anolyte when compared to catholyte. The weight loss of the anode was in the following order 0.615 > 0.307 > 0.123 mA/cm2 and the cathode corrosion rate was vice versa. Peroxide production was also noticed at the anolyte, which may encourage the degradation of the total organic content (TOC) in the soil. The OCP (open circuit potential) of SS316L was about +75 mV vs SCE in the soil extract; while adding acetic acid, the potential shifted to the positive side, to about +380 mV vs SCE. The breakdown potential and the range of passivation potential were higher in acetic acid added system when compared to other systems. Pitting was observed on both the anode and cathode within 48 h during the EK process. The present study concludes that SS is not a proper electrode material for the EK process.

  1. MIX and match: mobile T6SS MIX-effectors enhance bacterial fitness

    PubMed Central

    Salomon, Dor

    2016-01-01

    ABSTRACT Protein secretion systems that mediate interbacterial competition secret a wide repertoire of antibacterial toxins. A major player in these competitions is the newly discovered bacterial type VI secretion system (T6SS). We recently found that a subset of polymorphic MIX-effectors, which are a widespread class of effectors secreted by T6SSs, are horizontally shared between marine bacteria and are used to diversify their T6SS effector repertoires, thus enhancing their environmental fitness. In this commentary, I expand on the ideas that were introduced in the previous report, and further speculate on the possible mobility of other MIX-effectors. In addition, I discuss the possible role of horizontal gene transfer in the dissemination of MIX-effectors through bacterial genomes, as well as its possible role in diversifying the T6SS effector repertoire. PMID:27066305

  2. SS/RCS surface tension propellant acquisition/expulsion tankage technology program

    NASA Technical Reports Server (NTRS)

    1974-01-01

    An evaluation of published propellant physical property data together with bubble point tests of fine-mesh screen in propellants, was conducted. The effort consisted of: (1) the collection and evaluation of pertinent physical property data for hydrazine (N2H4), monomethylhydrazine (MMH), and nitrogen tetroxide (N2O4); (2) testing to determine the effect of dissolved pressurant gas, temperature, purity, and system cleanliness or contamination on system bubble point, and (3) the compilation and publishing of both the literature and test results. The space shuttle reaction control system (SS/RCS) is a bipropellant system using N2O4 and MMH, while the auxiliary power system (SS/APU) employs monopropellant N2H4. Since both the RCS and the APU use a surface tension device for propellant acquisition, the propellant properties of interest are those which impact the design and operation of surface tension systems. Information on propellant density, viscosity, surface tension, and contact angle was collected, compiled, and evaluated.

  3. Consolidated Laser-Induced Fluorescence Diagnostic Systems for the NASA Ames Arc Jet Facilities

    NASA Technical Reports Server (NTRS)

    Grinstead, Jay H.; Wilder, Michael C.; Porter, Barry J.; Brown, Jeffrey D.; Yeung, Dickson; Battazzo, Stephen J.; Brubaker, Timothy R.

    2016-01-01

    The spectroscopic diagnostic technique of two photon absorption laser-induced fluorescence (LIF) of atomic species for non-intrusive arc jet flow property measurement was first implemented at NASA Ames in the mid-1990s. In 2013-2014, NASA combined the agency's large-scale arc jet test capabilities at NASA Ames. Concurrent with that effort, the agency also sponsored a project to establish two comprehensive LIF diagnostic systems for the Aerodynamic Heating Facility (AHF) and Interaction Heating Facility (IHF) arc jets. The scope of the project enabled further engineering development of the existing IHF LIF system as well as the complete reconstruction of the AHF LIF system. The updated LIF systems are identical in design and capability. They represent the culmination of over 20 years of development experience in transitioning a specialized laboratory research tool into a measurement system for large-scale, high-demand test facilities. This paper will document the latest improvements of the LIF system design and demonstrations of the redeveloped AHF and IHF LIF systems.

  4. Study of Jet-Propulsion System Comprising Blower, Burner, and Nozzle

    NASA Technical Reports Server (NTRS)

    Hall, Eldon W

    1944-01-01

    A study was made of the performance of a jet-propulsion system composed of an engine-driven blower, a combustion chamber, and a discharge nozzle. A simplified analysis is made of this system for the purpose of showing in concise form the effect of the important design variables and operating conditions on jet thrust, thrust horsepower, and fuel consumption. Curves are presented that permit a rapid evaluation of the performance of this system for a range of operating conditions. The performance for an illustrative case of a power plant of the type under consideration id discussed in detail. It is shown that for a given airplane velocity the jet thrust horsepower depends mainly on the blower power and the amount of fuel burned in the jet; the higher the thrust horsepower is for a given blower power, the higher the fuel consumption per thrust horsepower. Within limits the amount of air pumped has only a secondary effect on the thrust horsepower and efficiency. A lower limit on air flow for a given fuel flow occurs where the combustion-chamber temperature becomes excessive on the basis of the strength of the structure. As the air-flow rate is increased, an upper limit is reached where, for a given blower power, fuel-flow rate, and combustion-chamber size, further increase in air flow causes a decrease in power and efficiency. This decrease in power is caused by excessive velocity through the combustion chamber, attended by an excessive pressure drop caused by momentum changes occurring during combustion.

  5. A Functional Description of a Digital Flight Test System for Navigation and Guidance Research in the Terminal Area

    NASA Technical Reports Server (NTRS)

    Hegarty, D. M.

    1974-01-01

    A guidance, navigation, and control system, the Simulated Shuttle Flight Test System (SS-FTS), when interfaced with existing aircraft systems, provides a research facility for studying concepts for landing the space shuttle orbiter and conventional jet aircraft. The SS-FTS, which includes a general-purpose computer, performs all computations for precisely following a prescribed approach trajectory while properly managing the vehicle energy to allow safe arrival at the runway and landing within prescribed dispersions. The system contains hardware and software provisions for navigation with several combinations of possible navigation aids that have been suggested for the shuttle. The SS-FTS can be reconfigured to study different guidance and navigation concepts by changing only the computer software, and adapted to receive different radio navigation information through minimum hardware changes. All control laws, logic, and mode interlocks reside solely in the computer software.

  6. Effectiveness of bomber deployed autonomous airborne vehicles in finding rail mobile SS-24s

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Abey, A.E.; Erickson, S.A.; Norquist, P.D.

    1990-08-01

    Computer simulation predictions of the effectiveness of autonomous airborne vehicles in finding rail mobile SS-24s are presented. Effectiveness is discussed for several autonomous airborne vehicle endurances and survivabilities for the search area southwest of Moscow. The effect of where the Soviets place the SS-24s on the rail network was also investigated. The simulation predicts significant variations in the ability of a multi-autonomous airborne vehicle system to find SS-24s with these parameters. 12 figs., 1 tab.

  7. A Universal Scaling for the Energetics of Relativistic Jets From Black Hole Systems

    NASA Technical Reports Server (NTRS)

    Nemmen, R. S.; Georganopoulos, M.; Guiriec, S.; Meyer, E. T.; Gehrels, N.; Sambruna, R. M.

    2013-01-01

    Black holes generate collimated, relativistic jets which have been observed in gamma-ray bursts (GRBs), microquasars, and at the center of some galaxies (active galactic nuclei; AGN). How jet physics scales from stellar black holes in GRBs to the supermassive ones in AGNs is still unknown. Here we show that jets produced by AGNs and GRBs exhibit the same correlation between the kinetic power carried by accelerated particles and the gamma-ray luminosity, with AGNs and GRBs lying at the low and high-luminosity ends, respectively, of the correlation. This result implies that the efficiency of energy dissipation in jets produced in black hole systems is similar over 10 orders of magnitude in jet power, establishing a physical analogy between AGN and GRBs.

  8. A universal scaling for the energetics of relativistic jets from black hole systems.

    PubMed

    Nemmen, R S; Georganopoulos, M; Guiriec, S; Meyer, E T; Gehrels, N; Sambruna, R M

    2012-12-14

    Black holes generate collimated, relativistic jets, which have been observed in gamma-ray bursts (GRBs), microquasars, and at the center of some galaxies [active galactic nuclei (AGN)]. How jet physics scales from stellar black holes in GRBs to the supermassive ones in AGN is still unknown. Here, we show that jets produced by AGN and GRBs exhibit the same correlation between the kinetic power carried by accelerated particles and the gamma-ray luminosity, with AGN and GRBs lying at the low- and high-luminosity ends, respectively, of the correlation. This result implies that the efficiency of energy dissipation in jets produced in black hole systems is similar over 10 orders of magnitude in jet power, establishing a physical analogy between AGN and GRBs.

  9. The Data Acquisition and Control Systems of the Jet Noise Laboratory at the NASA Langley Research Center

    NASA Technical Reports Server (NTRS)

    Jansen, B. J., Jr.

    1998-01-01

    The features of the data acquisition and control systems of the NASA Langley Research Center's Jet Noise Laboratory are presented. The Jet Noise Laboratory is a facility that simulates realistic mixed flow turbofan jet engine nozzle exhaust systems in simulated flight. The system is capable of acquiring data for a complete take-off assessment of noise and nozzle performance. This paper describes the development of an integrated system to control and measure the behavior of model jet nozzles featuring dual independent high pressure combusting air streams with wind tunnel flow. The acquisition and control system is capable of simultaneous measurement of forces, moments, static and dynamic model pressures and temperatures, and jet noise. The design concepts for the coordination of the control computers and multiple data acquisition computers and instruments are discussed. The control system design and implementation are explained, describing the features, equipment, and the experiences of using a primarily Personal Computer based system. Areas for future development are examined.

  10. Escherichia coli type III secretion system 2: a new kind of T3SS?

    PubMed

    Zhou, Mingxu; Guo, Zhiyan; Duan, Qiangde; Hardwidge, Philip R; Zhu, Guoqiang

    2014-03-19

    Type III secretion systems (T3SSs) are employed by Gram-negative bacteria to deliver effector proteins into the cytoplasm of infected host cells. Enteropathogenic Escherichia coli use a T3SS to deliver effector proteins that result in the creation of the attaching and effacing lesions. The genome sequence of the Escherichia coli pathotype O157:H7 revealed the existence of a gene cluster encoding components of a second type III secretion system, the E. coli type III secretion system 2 (ETT2). Researchers have revealed that, although ETT2 may not be a functional secretion system in most (or all) strains, it still plays an important role in bacterial virulence. This article summarizes current knowledge regarding the E. coli ETT2, including its genetic characteristics, prevalence, function, association with virulence, and prospects for future work.

  11. Promotion of plant growth by Pseudomonas fluorescens strain SS101 via novel volatile organic compounds.

    PubMed

    Park, Yong-Soon; Dutta, Swarnalee; Ann, Mina; Raaijmakers, Jos M; Park, Kyungseok

    2015-05-29

    Volatile organic compounds (VOCs) from plant growth-promoting rhizobacteria (PGPR) play key roles in modulating plant growth and induced systemic resistance (ISR) to pathogens. Despite their significance, the physiological functions of the specific VOCs produced by Pseudomonas fluorescens SS101 (Pf.SS101) have not been precisely elucidated. The effects of Pf.SS101 and its VOCs on augmentation of plant growth promotion were investigated in vitro and in planta. A significant growth promotion was observed in plants exposed Pf.SS101 under both conditions, suggesting that its VOCs play a key role in promoting plant growth. Solid-phase micro-extraction (SPME) and a gas chromatography-mass spectrophotometer (GC-MS) system were used to characterize the VOCs emitted by Pf.SS101 and 11 different compounds were detected in samples inoculated this bacterium, including 13-Tetradecadien-1-ol, 2-butanone and 2-Methyl-n-1-tridecene. Application of these compounds resulted in enhanced plant growth. This study suggests that Pf.SS101 promotes the growth of plants via the release of VOCs including 13-Tetradecadien-1-ol, 2-butanone and 2-Methyl-n-1-tridecene, thus increasing understanding of the role of VOCs in plant-bacterial inter-communication. Copyright © 2015 Elsevier Inc. All rights reserved.

  12. Deriving the Generalized Power and Efficiency Equations for Jet Propulsion Systems

    NASA Astrophysics Data System (ADS)

    Lee, Hsing-Juin; Chang, Chih-Luong

    The kinetic power and efficiency equations for general jet propulsion systems are classically given in a much cursory, incomplete, and ununified format. This situation prohibits the propulsion designer from seeing the panorama of interrelated propulsion parameters and effects. And in some cases, it may lead to an energy-inefficient propulsion system design, or induce significant offset in propulsion performance as demonstrated in this study. Thus, herein we attempt to clarify some related concepts and to rigorously derive the associated generalized equations with a complete spectrum of physical parameters to be manipulated in quest of better performance. By a highly efficient interweaved transport scheme, we have derived the following equations for general jet propulsion systems: i.e., generalized total kinetic power, generalized kinetic power delivered to the jet propulsion system, generalized thrust power, generalized available propulsion power, and relevant generalized propulsive, thermal, and overall efficiency equations. Further, the variants of these equations under special conditions are also considered. For taking advantage of the above propulsion theories, we also illustrate some novel propulsion strategies in the final discussion, such as the dive-before-climb launch of rocket from highland mountain on eastbound rail, with perhaps minisatellites as the payloads.

  13. Twin Jet Effects on Noise of Round and Rectangular Jets: Experiment and Model

    NASA Technical Reports Server (NTRS)

    Bozak, Rick

    2014-01-01

    Many subsonic and supersonic aircraft concepts proposed by NASA's Fundamental Aeronautics Program have asymmetric, integrated propulsion systems. The asymmetries in the exhaust of these propulsion systems create an asymmetric acoustic field. The asymmetries investigated in the current study are from twin jets and rectangular nozzles. Each effect produces its own variation of the acoustic field. An empirical model was developed to predict the acoustic field variation from round twin jets with twin jet spacing from 2.6 to 5.6, where s is the center-to-center spacing over the jet diameter. The model includes parameters to account for the effects of twin jet spacing, jet static temperature ratio, flight Mach number, frequency, and observer angle (both polar and azimuthal angles). The model was then applied to twin 2:1 and 8:1 aspect ratio nozzles to determine the impact of jet aspect ratio. For the round and rectangular jets, the use of the model reduces the average magnitude of the error over all frequencies, observation angles, and jet spacings by approximately 0.5dB when compared against the assumption of adding two jets incoherently.

  14. Spiral jet

    NASA Astrophysics Data System (ADS)

    Istomin, Ya N.

    2018-05-01

    We show that a quasi-cylindrical configuration of a jet in the central region, where direct electric current flows, is confined in a radial equilibrium by a spiral wave at the periphery of a jet. A spiral wave means that in a coordinate system moving with the velocity of the matter along the axis of the jet, all quantities are proportional to exp {ik∥z + imϕ}, z is the longitudinal coordinate, and ϕ is the azimuthal angle. The luminosity of such a jet corresponds to observations. It is also shown that the jet slowly expands with distance z from its base by the power law, R(z) ∝ zk, where the exponent k varies from ≃0.5 to ≃1.

  15. Methodology for Flight Relevant Arc-Jet Testing of Flexible Thermal Protection Systems

    NASA Technical Reports Server (NTRS)

    Mazaheri, Alireza; Bruce, Walter E., III; Mesick, Nathaniel J.; Sutton, Kenneth

    2013-01-01

    A methodology to correlate flight aeroheating environments to the arc-jet environment is presented. For a desired hot-wall flight heating rate, the methodology provides the arcjet bulk enthalpy for the corresponding cold-wall heating rate. A series of analyses were conducted to examine the effects of the test sample model holder geometry to the overall performance of the test sample. The analyses were compared with arc-jet test samples and challenges and issues are presented. The transient flight environment was calculated for the Hypersonic Inflatable Aerodynamic Decelerator (HIAD) Earth Atmospheric Reentry Test (HEART) vehicle, which is a planned demonstration vehicle using a large inflatable, flexible thermal protection system to reenter the Earth's atmosphere from the International Space Station. A series of correlations were developed to define the relevant arc-jet test environment to properly approximate the HEART flight environment. The computed arcjet environments were compared with the measured arc-jet values to define the uncertainty of the correlated environment. The results show that for a given flight surface heat flux and a fully-catalytic TPS, the flight relevant arc-jet heat flux increases with the arc-jet bulk enthalpy while for a non-catalytic TPS the arc-jet heat flux decreases with the bulk enthalpy.

  16. Hydrodynamic stability of jets produced by mass accreting systems

    NASA Technical Reports Server (NTRS)

    Hardee, P. E.

    1982-01-01

    The existing model for pulsed X-ray emission from the source Hercules X-1 is reviewed. A necessary part of this model is a processing accretion disk which turns the source on and off with 35 day cycle. It is usually assumed that precession of the primary star in this binary system, Hz Hercules, slaves the disk to its precession rate. This model can account for the system behavior in a qualitative manner. Precession of Hz Hercules with 35 day period requires precession of the binary orbit. Pulse arrival times from Herc X-1 have been analyzed for orbital precession. The inclusion of precession does not significantly improve the results obtained assuming a non-precessing orbit. The fluid dynamical stability of extra-galactic jets and the possible consequences of Kelvin-Helmholtz instability at the jet surface external medium interface are considered.

  17. Jet fuel-induced immunotoxicity.

    PubMed

    Harris, D T; Sakiestewa, D; Titone, D; Robledo, R F; Young, R S; Witten, M

    2000-09-01

    Chronic exposure to jet fuel has been shown to cause human liver dysfunction, emotional dysfunction, abnormal electroencephalograms, shortened attention spans, and to decrease sensorimotor speed (3-5). Exposure to potential environmental toxicants such as jet fuel may have significant effects on host systems beyond those readily visible (e.g., physiology, cardiology, respiratory, etc.), e.g., the immune system. Significant changes in immune function, even if short-lived, may have serious consequences for the exposed host that may impinge affect susceptibility to infectious agents. Major alterations in immune function that are long lasting may result in an increased likelihood of development and/or progression of cancer, as well as autoimmune diseases. In the current study mice were exposed 1 h/day for 7 days to a 1000-mg/m3 concentration of aerosolized jet fuel obtained from various sources (JP-8, JP-8+100 and Jet A1) and of differing compositions to simulate occupational exposures. Twenty-four hours after the last exposure the mice were analyzed for effects on the immune system. It was observed that exposure to all jet fuel sources examined had detrimental effects on the immune system. Decreases in viable immune cell numbers and immune organ weights were found. Jet fuel exposure resulted in differential losses of immune cell populations in the thymus. Further, jet fuel exposure resulted in significantly decreased immune function, as analyzed by mitogenesis assays. Suppressed immune function could not be overcome by the addition of exogenous growth factors known to stimulate immune function. Thus, short-term, low-concentration exposure of mice to aerosolized jet fuel, regardless of source or composition, caused significant deleterious effects on the immune system.

  18. Validation of a reduced-order jet model for subsonic and underexpanded hydrogen jets

    DOE PAGES

    Li, Xuefang; Hecht, Ethan S.; Christopher, David M.

    2016-01-01

    Much effort has been made to model hydrogen releases from leaks during potential failures of hydrogen storage systems. A reduced-order jet model can be used to quickly characterize these flows, with low computational cost. Notional nozzle models are often used to avoid modeling the complex shock structures produced by the underexpanded jets by determining an “effective” source to produce the observed downstream trends. In our work, the mean hydrogen concentration fields were measured in a series of subsonic and underexpanded jets using a planar laser Rayleigh scattering system. Furthermore, we compared the experimental data to a reduced order jet modelmore » for subsonic flows and a notional nozzle model coupled to the jet model for underexpanded jets. The values of some key model parameters were determined by comparisons with the experimental data. Finally, the coupled model was also validated against hydrogen concentrations measurements for 100 and 200 bar hydrogen jets with the predictions agreeing well with data in the literature.« less

  19. Simultaneous IUE and Ground Based Observations of SS Cygni and HL Canis Majoris

    NASA Astrophysics Data System (ADS)

    Mansperger, C. S.; Kaitchuck, R. H.; Garnavich, P.; Dinshaw, N.

    1993-05-01

    SS Cyg and HL CMa were observed by IUE for three consecutive nights in November of 1992. During the first two nights, simultaneous photometric ground based observations of SS Cyg were made at the Ball State University Observatory. SS Cyg and HL CMa were observed simultaneously with the 90-inch telescope at the Steward Observatory on the last two nights of this run. These spectroscopic observations covered the wavelength range of 4100 Angstroms to 5000 Angstroms, while the spectra taken with the short wavelength camera on IUE resulted in wavelength coverage from 1150 Angstroms to 1980 Angstroms. SS Cyg is a U Gem type dwarf nova with an orbital period of 6.6 hours. Good simultaneous UV and optical orbital coverage was obtained for this system. HL CMa is a Z Cam type dwarf nova with an outburst period of 18 days. The AAVSO reports that this system was in outburst 4 days after the observing run. Therefore, HL CMa may have been in a preoutburst state during these observations. The C IV and H \\beta emission lines appeared to have weakened during this time.

  20. A Precessing Jet in the CH Cyg Symbiotic System

    NASA Astrophysics Data System (ADS)

    Karovska, Margarita; Gaetz, Terrance J.; Carilli, Christopher L.; Hack, Warren; Raymond, John C.; Lee, Nicholas P.

    2010-02-01

    Jets have been detected in only a few symbiotic binaries to date, and CH Cyg is one of them. In 2001, a non-relativistic jet was detected in CH Cyg for the first time in X-rays. We carried out coordinated Chandra, Hubble Space Telescope (HST), and VLA observations in 2008 to study the propagation of this jet and its interaction with the circumbinary medium. We detected the jet with Chandra and HST and determined that the apex has expanded to the south from ~300 AU to ~1400 AU, with the shock front propagating with velocity <100 km s-1. The shock front has significantly slowed down since 2001. Unexpectedly, we also discovered a powerful jet in the NE-SW direction, in the X-ray, optical and radio. This jet has a multi-component structure, including an inner jet and a counterjet at ~170 AU, and a SW component ending in several clumps extending out to ~750 AU. The structure of the jet and the curvature of the outer portion of the SW jet suggest an episodically powered precessing jet or a continuous precessing jet with occasional mass ejections or pulses. We carried out detailed spatial mapping of the X-ray emission and correlation with the optical and radio emission. X-ray spectra were extracted from the central source, inner NE counterjet, and the brightest clump at a distance of ~500 AU from the central source. We discuss the initial results of our analyses, including the multi-component spectral fitting of the jet components and of the central source.

  1. Investigation of Impact Jets Flow in Heat Sink Device of Closed-Circuit Cooling Systems

    NASA Astrophysics Data System (ADS)

    Tokarev, D. A.; Yenivatov, V. V.; Sokolov, S. S.; Erofeev, V. L.

    2018-03-01

    The flow simulations of impact jets in the heat sink device of the closed-circuit cooling systems are presented. The analysis of the rate of fluid flow in the heat sink device with the jet supply coolant is given.

  2. Feasibility of AN Ecrh System for Jet:. Plant Layout, Auxiliaries and Services

    NASA Astrophysics Data System (ADS)

    Lennholm, M.; Bouquey, F.; Braune, H.; Farthing, J.; Garavaglia, S.; Giruzzi, G.; Granucci, G.; Jennison, M.; Parkin, A.

    2011-02-01

    A study conducted over the last year to asses the desirability and feasibility of installing an ECRH system on the JET tokamak has concluded that such a system is indeed both desirable and feasible. Details of physics studies, launcher and transmission line design, and power supplies are presented elsewhere in these proceedings. This paper concentrates on the logistical implications of installing this system at JET. The paper addresses issues such as port allocation and plant location. The study has concluded that a new building will be needed to house the ECRH plant. Building layout proposals are presented together with considerations regarding the required auxiliary equipment.

  3. THE RADIO JET ASSOCIATED WITH THE MULTIPLE V380 ORI SYSTEM

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rodríguez, Luis F.; Yam, J. Omar; Carrasco-González, Carlos

    The giant Herbig–Haro object 222 extends over ∼6′ in the plane of the sky, with a bow shock morphology. The identification of its exciting source has remained uncertain over the years. A non-thermal radio source located at the core of the shock structure was proposed to be the exciting source. However, Very Large Array studies showed that the radio source has a clear morphology of radio galaxy and a lack of flux variations or proper motions, favoring an extragalactic origin. Recently, an optical–IR study proposed that this giant HH object is driven by the multiple stellar system V380 Ori, locatedmore » about 23′ to the SE of HH 222. The exciting sources of HH systems are usually detected as weak free–free emitters at centimeter wavelengths. Here, we report the detection of an elongated radio source associated with the Herbig Be star or with its close infrared companion in the multiple V380 Ori system. This radio source has the characteristics of a thermal radio jet and is aligned with the direction of the giant outflow defined by HH 222 and its suggested counterpart to the SE, HH 1041. We propose that this radio jet traces the origin of the large scale HH outflow. Assuming that the jet arises from the Herbig Be star, the radio luminosity is a few times smaller than the value expected from the radio–bolometric correlation for radio jets, confirming that this is a more evolved object than those used to establish the correlation.« less

  4. A new prototype of an electronic jet-ventilator and its humidification system

    PubMed Central

    Kraincuk, Paul; Kepka, Anton; Ihra, Gerald; Schabernig, Christa; Aloy, Alexander

    1999-01-01

    Background: Adequate humidification in long-term jet ventilation is a critical aspect in terms of clinical safety. Aim: To assess a prototype of an electronic jet-ventilator and its humidification system. Methods: Forty patients with respiratory insufficiency were randomly allocated to one of four groups. The criterion for inclusion in this study was respiratory insufficiency exhibiting a Murray score above 2. The four groups of patients were ventilated with three different respirators and four different humidification systems. Patients in groups A and B received superimposed high-frequency jet ventilation (SHFJV) by an electronic jet-ventilator either with (group A) or without (group B) an additional humidification system. Patients in group C received high-frequency percussive ventilation (HFPV) by a pneumatic high-frequency respirator, using a hot water humidifier for warming and moistening the inspiration gas. Patients in group D received conventional mechanical ventilation using a standard intensive care unit respirator with a standard humidification system. SHFJV and HFPV were used for a period of 100 h (4days). Results: A significantly low inspiration gas temperature was noted in patients in group B, initially (27.2 ± 2.5°C) and after 2 days (28.0 ± 1.6°C) (P < 0.05). The percentage of relative humidity of the inspiration gas in patients in group B was also initially significantly low (69.8 ± 4.1%; P < 0.05) but rose to an average of 98 ± 2.8% after 2 h. The average percentage across all four groups amounted to 98 ± 0.4% after 2 h. Inflammation of the tracheal mucosa was found in patients in group B and the mucosal injury score (MIS) was significantly higher than in all the other groups. Patients in groups A, C and D showed no severe evidence of airway damage, exhibiting adequate values of relative humidity and temperature of the inspired gas. Conclusion: The problems of humidification associated with jet ventilation can be fully prevented by using

  5. KiSS-1 and reproduction: focus on its role in the metabolic regulation of fertility.

    PubMed

    Tena-Sempere, Manuel

    2006-01-01

    Unraveling of the master role of kisspeptins, the products of the KiSS-1 gene, and their receptor, GPR54, in the control of reproduction has been a major breakthrough in contemporary neuroendocrinology. Indeed, since the disclosure of their reproductive dimension in late 2003, an ever-growing number of genetic, molecular, physiologic and pharmacological studies have defined the crucial role of KiSS-1 neurons as central processors for the dynamic regulation of the gonadotropic axis and its full activation at puberty. Yet, the potential role of the hypothalamic KiSS-1 system as an intermediary factor for the well-known interplay between energy status and reproduction initially received little attention. Recent data, however, strongly suggest a prominent role of KiSS-1 in the metabolic control of fertility, as expression of KiSS-1 gene at the hypothalamus is down-regulated in conditions of negative energy balance and kisspeptin administration is capable of overcoming the hypogonadotropic state observed in undernutrition and disturbed metabolic conditions. Leptin, the adipocyte hormone signaling the size of body energy stores, is likely to play a pivotal role in the metabolic control of the KiSS-1 system, since kisspeptin neurons express leptin receptors and leptin is able to normalize defective KiSS-1 gene expression in models of impaired gonadotropin secretion linked to hypoleptinemia, such as the ob/ob mouse and streptozotocin-induced diabetic rat. In sum, these data provide strong evidence for a central role of kisspeptins and GPR54 as molecular conduits for the metabolic regulation of reproductive function - a phenomenon with potential physiopathologic and therapeutic implications.

  6. Effect of surface thickness on the wetting front velocity during jet impingement surface cooling

    NASA Astrophysics Data System (ADS)

    Agrawal, Chitranjan; Gotherwal, Deepesh; Singh, Chandradeep; Singh, Charan

    2017-02-01

    A hot stainless steel (SS-304) surface of 450 ± 10 °C initial temperature is cooled with a normally impinging round water jet. The experiments have been performed for the surface of different thickness e.g. 1, 2, 3 mm and jet Reynolds number in the range of Re = 26,500-48,000. The cooling performance of the hot test surface is evaluated on the basis of wetting front velocity. The wetting front velocity is determined for 10-40 mm downstream spatial locations away from the stagnation point. It has been observed that the wetting front velocity increase with the rise in jet flow rate, however, diminishes towards the downstream spatial location and with the rise in surface thickness. The proposed correlation for the dimensionless wetting front velocity predicts the experimental data well within the error band of ±30 %, whereas, 75 % of experimental data lies within the range of ±20 %.

  7. Binary system and jet precession and expansion in G35.20-0.74N

    NASA Astrophysics Data System (ADS)

    Beltrán, M. T.; Cesaroni, R.; Moscadelli, L.; Sánchez-Monge, Á.; Hirota, T.; Kumar, M. S. N.

    2016-09-01

    Context. Atacama Large Millimeter/submillimeter Array (ALMA) observations of the high-mass star-forming region G35.20-0.74N have revealed the presence of a Keplerian disk in core B rotating about a massive object of 18 M⊙, as computed from the velocity field. The luminosity of such a massive star would be comparable to (or higher than) the luminosity of the whole star-forming region. To solve this problem it has been proposed that core B could harbor a binary system. This could also explain the possible precession of the radio jet associated with this core, which has been suggested by its S-shaped morphology. Aims: We establish the origin of the free-free emission from core B and investigate the existence of a binary system at the center of this massive core and the possible precession of the radio jet. Methods: We carried out VLA continuum observations of G35.20-0.74N at 2 cm in the B configuration and at 1.3 cm and 7 mm in the A and B configurations. The bandwidth at 7 mm covers the CH3OH maser line at 44.069 GHz. Continuum images at 6 and 3.6 cm in the A configuration were obtained from the VLA archive. We also carried out VERA observations of the H2O maser line at 22.235 GHz. Results: The observations have revealed the presence of a binary system of UC/HC Hii regions at the geometrical center of the radio jet in G35.20-0.74N. This binary system, which is associated with a Keplerian rotating disk, consists of two B-type stars of 11 and 6 M⊙. The S-shaped morphology of the radio jet has been successfully explained as being due to precession produced by the binary system. The analysis of the precession of the radio jet has allowed us to better interpret the IR emission in the region, which would be not tracing a wide-angle cavity open by a single outflow with a position angle of ~55°, but two different flows: a precessing one in the NE-SW direction associated with the radio jet, and a second one in an almost E-W direction. Comparison of the radio jet images

  8. Strong circumstantial proofs about the intermediate polar nature of the cataclysmic variable SS Cygni

    NASA Astrophysics Data System (ADS)

    Giovannelli, Franco; Sabau-Graziati, Lola

    This paper is the updated version of that published in the proceedings of the Integral/Bart Workshop 2011 (Giovannelli & Sabau-Graziati, 2012a). SS Cyg is a cataclysmic variable usually classified as dwarf nova, a subclass of the non-magnetic cataclysmic variables. The goal of this paper is to demonstrate -- on the basis of the many arguments and circumstantial proofs derived from the numerous multifrequency data obtained from the SS Cyg binary system -- that such classification is wrong and that the intermediate polar nature of SS Cyg is the most probable. We derive the magnetic field intensity at the surface of the white dwarf in SS Cyg as B ≃ 1.6 ± 0.7 MG. This value is in complete agreement with the evaluation made by Fabbiano et al. (1981) (B< 1.9 MG) using simultaneous X-ray, UV, and optical data.

  9. A solenoid failure detection system for cold gas attitude control jet valves

    NASA Technical Reports Server (NTRS)

    Johnston, P. A.

    1970-01-01

    The development of a solenoid valve failure detection system is described. The technique requires the addition of a radioactive gas to the propellant of a cold gas jet attitude control system. Solenoid failure is detected with an avalanche radiation detector located in the jet nozzle which senses the radiation emitted by the leaking radioactive gas. Measurements of carbon monoxide leakage rates through a Mariner type solenoid valve are presented as a function of gas activity and detector configuration. A cylindrical avalanche detector with a factor of 40 improvement in leak sensitivity is proposed for flight systems because it allows the quantity of radioactive gas that must be added to the propellant to be reduced to a practical level.

  10. A New Generation of Real-Time Systems in the JET Tokamak

    NASA Astrophysics Data System (ADS)

    Alves, Diogo; Neto, Andre C.; Valcarcel, Daniel F.; Felton, Robert; Lopez, Juan M.; Barbalace, Antonio; Boncagni, Luca; Card, Peter; De Tommasi, Gianmaria; Goodyear, Alex; Jachmich, Stefan; Lomas, Peter J.; Maviglia, Francesco; McCullen, Paul; Murari, Andrea; Rainford, Mark; Reux, Cedric; Rimini, Fernanda; Sartori, Filippo; Stephen, Adam V.; Vega, Jesus; Vitelli, Riccardo; Zabeo, Luca; Zastrow, Klaus-Dieter

    2014-04-01

    Recently, a new recipe for developing and deploying real-time systems has become increasingly adopted in the JET tokamak. Powered by the advent of x86 multi-core technology and the reliability of JET's well established Real-Time Data Network (RTDN) to handle all real-time I/O, an official Linux vanilla kernel has been demonstrated to be able to provide real-time performance to user-space applications that are required to meet stringent timing constraints. In particular, a careful rearrangement of the Interrupt ReQuests' (IRQs) affinities together with the kernel's CPU isolation mechanism allows one to obtain either soft or hard real-time behavior depending on the synchronization mechanism adopted. Finally, the Multithreaded Application Real-Time executor (MARTe) framework is used for building applications particularly optimised for exploring multi-core architectures. In the past year, four new systems based on this philosophy have been installed and are now part of JET's routine operation. The focus of the present work is on the configuration aspects that enable these new systems' real-time capability. Details are given about the common real-time configuration of these systems, followed by a brief description of each system together with results regarding their real-time performance. A cycle time jitter analysis of a user-space MARTe based application synchronizing over a network is also presented. The goal is to compare its deterministic performance while running on a vanilla and on a Messaging Real time Grid (MRG) Linux kernel.

  11. Dichotomy of Solar Coronal Jets: Standard Jets and Blowout Jets

    NASA Technical Reports Server (NTRS)

    Moore, R. L.; Cirtain, J. W.; Sterling, A. C.; Falconer, D. A.

    2010-01-01

    By examining many X-ray jets in Hinode/XRT coronal X-ray movies of the polar coronal holes, we found that there is a dichotomy of polar X-ray jets. About two thirds fit the standard reconnection picture for coronal jets, and about one third are another type. We present observations indicating that the non-standard jets are counterparts of erupting-loop H alpha macrospicules, jets in which the jet-base magnetic arch undergoes a miniature version of the blowout eruptions that produce major CMEs. From the coronal X-ray movies we present in detail two typical standard X-ray jets and two typical blowout X-ray jets that were also caught in He II 304 Angstrom snapshots from STEREO/EUVI. The distinguishing features of blowout X-ray jets are (1) X-ray brightening inside the base arch in addition to the outside bright point that standard jets have, (2) blowout eruption of the base arch's core field, often carrying a filament of cool (T 10(exp 4) - 10(exp 5) K) plasma, and (3) an extra jet-spire strand rooted close to the bright point. We present cartoons showing how reconnection during blowout eruption of the base arch could produce the observed features of blowout X-ray jets. We infer that (1) the standard-jet/blowout-jet dichotomy of coronal jets results from the dichotomy of base arches that do not have and base arches that do have enough shear and twist to erupt open, and (2) there is a large class of spicules that are standard jets and a comparably large class of spicules that are blowout jets.

  12. True logarithmic amplification of frequency clock in SS-OCT for calibration

    PubMed Central

    Liu, Bin; Azimi, Ehsan; Brezinski, Mark E.

    2011-01-01

    With swept source optical coherence tomography (SS-OCT), imprecise signal calibration prevents optimal imaging of biological tissues such as coronary artery. This work demonstrates an approach using a true logarithmic amplifier to precondition the clock signal, with the effort to minimize the noises and phase errors for optimal calibration. This method was validated and tested with a high-speed SS-OCT. The experimental results manifest its superior ability on optimization of the calibration and improvement of the imaging performance. Particularly, this hardware-based approach is suitable for real-time calibration in a high-speed system where computation time is constrained. PMID:21698036

  13. Construction, characterization and evaluation of the protective efficacy of the Streptococcus suis double mutant strain ΔSsPep/ΔSsPspC as a live vaccine candidate in mice.

    PubMed

    Hu, Jin; You, Wujin; Wang, Bin; Hu, Xueying; Tan, Chen; Liu, Jinlin; Chen, Huanchun; Bei, Weicheng

    2015-01-01

    Streptococcus suis serotype 2 (S. suis 2) causes sepsis and meningitis in piglets and humans, and results in one of the most serious bacterial diseases affecting the production of commercial pigs around the world. Due to the failure of the current inactivated vaccine to protect against the disease, development of a new attenuated live vaccine against S. suis 2 by deleting essential virulence factors is urgently needed. We have previously reported the construction and characterization of an SsPep single gene deletion mutant strain ΔSsPep based on S. suis 2. Our previous results have shown that SsPep plays a critical role in the pathogenesis of S. suis 2. In this study, a precisely defined double-deletion mutant ΔSsPep/ΔSsPspC of S. suis 2 without antibiotic-resistance markers was constructed based on ΔSsPep, and the levels of virulence of the wild-type (WT) and ΔSsPep/ΔSsPspC were compared in a mouse experimental infection model. We demonstrated that the double mutant ΔSsPep/ΔSsPspC was less virulent than the WT, and could induce a noticeable antibody response. Analysis of IgG subclasses (IgG1 and IgG2a) indicated that both Th1 and Th2 responses were induced by ΔSsPep/ΔSsPspC, although the IgG2a (Th1) response predominated over the IgG1 (Th2) response. Moreover, ΔSsPep/ΔSsPspC could confer 90% protective efficacy against challenge with a lethal dose of fully virulent S. suis 2. Taken together, these data demonstrate that ΔSsPep/ΔSsPspC can be used as an effective live vaccine and provide a novel strategy against infection of S. suis 2. Copyright © 2014 Elsevier GmbH. All rights reserved.

  14. High-sensitivity survey of a pole-on disk-jet system around high mass YSOs

    NASA Astrophysics Data System (ADS)

    Motogi, Kazuhito; Walsh, Andrew; Hirota, Tomoya; Niinuma, Kotaro; Sugiyama, Koichiro; Fujisawa, Kenta; Yonekura, Yoshinori; Honma, Mareki; Sorai, Kazuo

    2013-10-01

    Recent theoretical works have suggested that detailed evolution of a high mass protostellar object highly depends on effective accretion rate and exact accretion geometry. Observational studies of the innermost accretion properties are, thus, an essential task in the ALMA era. High mass protostellar objects with a pole-on disk-jet system are, hence, excellent targets for such a study, since an outflow cavity reduces the total optical depth along the line-of-sight. Our previous studies have shown that some singular water maser sources called dominant blue-shifted masers (DBSMs) are plausible candidates of pole-on disk jet systems. There are, however, still two major problems as follows, (1) Some DBSMs can be a "fake", because of the significant variability of water masers. (2) It is difficult to verify the sources are really in pole-on geometry. The first problems can be checked with the thermal counterparts, and the second problem can be tested by morphologies of the class II CH3OH maser sources. We propose a high-sensitivity survey of real “pole-on” disk-jet systems towards the southern ten DBSMs. This new survey consists of multi-band observations between C/X/K/W bands. We will start from the C/X-continuum survey in this semester. Scientific goals in this semester are, (1) surveying radio jet activities with the C/X continuum emission, (2) estimating the inclination angle of disk-jet systems based on the morphologies of the CH3OH maser spots. (3) determining the exact positions of driving sources.

  15. Polyhedral Interpolation for Optimal Reaction Control System Jet Selection

    NASA Technical Reports Server (NTRS)

    Gefert, Leon P.; Wright, Theodore

    2014-01-01

    An efficient algorithm is described for interpolating optimal values for spacecraft Reaction Control System jet firing duty cycles. The algorithm uses the symmetrical geometry of the optimal solution to reduce the number of calculations and data storage requirements to a level that enables implementation on the small real time flight control systems used in spacecraft. The process minimizes acceleration direction errors, maximizes control authority, and minimizes fuel consumption.

  16. Deformations of free jets

    NASA Astrophysics Data System (ADS)

    Paruchuri, Srinivas

    This thesis studies three different problems. First we demonstrate that a flowing liquid jet can be controllably split into two separate subfilaments through the applications of a sufficiently strong tangential stress to the surface of the jet. In contrast, normal stresses can never split a liquid jet. We apply these results to observations of uncontrolled splitting of jets in electric fields. The experimental realization of controllable jet splitting would provide an entirely novel route for producing small polymeric fibers. In the second chapter we present an analytical model for the bending of liquid jets and sheets from temperature gradients, as recently observed by Chwalek et al. [Phys. Fluids, 14, L37 (2002)]. The bending arises from a local couple caused by Marangoni forces. The dependence of the bending angle on experimental parameters is presented, in qualitative agreement with reported experiments. The methodology gives a simple framework for understanding the mechanisms for jet and sheet bending. In chapter 4 we address the discrepancy between hydrodynamic theory of liquid jets, and the snap-off of narrow liquid jets observed in molecular dynamics (MD) simulations [23]. This has been previously attributed to the significant role of thermal fluctuations in nanofluidic systems. We argue that hydrodynamic description of such systems should include corrections to the Laplace pressure which result from the failure of the sharp interface assumption when the jet diameter becomes small enough. We show that this effect can in principle give rise to jet shapes similar to those observed in MD simulations, even when thermal fluctuations are completely neglected. Finally we summarize an algorithm developed to simulate droplet impact on a smooth surface.

  17. 30 CFR 56.7801 - Jet drills.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Jet drills. 56.7801 Section 56.7801 Mineral... HEALTH SAFETY AND HEALTH STANDARDS-SURFACE METAL AND NONMETAL MINES Drilling and Rotary Jet Piercing Rotary Jet Piercing § 56.7801 Jet drills. Jet piercing drills shall be provided with— (a) A system to...

  18. 30 CFR 56.7801 - Jet drills.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Jet drills. 56.7801 Section 56.7801 Mineral... HEALTH SAFETY AND HEALTH STANDARDS-SURFACE METAL AND NONMETAL MINES Drilling and Rotary Jet Piercing Rotary Jet Piercing § 56.7801 Jet drills. Jet piercing drills shall be provided with— (a) A system to...

  19. 30 CFR 56.7801 - Jet drills.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Jet drills. 56.7801 Section 56.7801 Mineral... HEALTH SAFETY AND HEALTH STANDARDS-SURFACE METAL AND NONMETAL MINES Drilling and Rotary Jet Piercing Rotary Jet Piercing § 56.7801 Jet drills. Jet piercing drills shall be provided with— (a) A system to...

  20. 30 CFR 56.7801 - Jet drills.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Jet drills. 56.7801 Section 56.7801 Mineral... HEALTH SAFETY AND HEALTH STANDARDS-SURFACE METAL AND NONMETAL MINES Drilling and Rotary Jet Piercing Rotary Jet Piercing § 56.7801 Jet drills. Jet piercing drills shall be provided with— (a) A system to...

  1. 30 CFR 56.7801 - Jet drills.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Jet drills. 56.7801 Section 56.7801 Mineral... HEALTH SAFETY AND HEALTH STANDARDS-SURFACE METAL AND NONMETAL MINES Drilling and Rotary Jet Piercing Rotary Jet Piercing § 56.7801 Jet drills. Jet piercing drills shall be provided with— (a) A system to...

  2. Lactic acid bacteria increase antiallergic effect of Artemisia princeps pampanini SS-1.

    PubMed

    Lee, Seung-Hoon; Shin, Yong-Wook; Bae, Eun-Ah; Lee, Bomi; Min, Sungwon; Baek, Nam-In; Chung, Hae-Gon; Kim, Nam-Jae; Kim, Dong-Hyun

    2006-09-01

    Artemisia princeps Pampanini, which is called Ssajuarissuk in Korean (SS-1), was fermented with lactic acid bacteria (LAB) and their passive cutaneous anaphylaxis reaction-inhibitory activity was investigated. Of these fermented agents, SS-1 extract fermented with Bifidobacterium infantis K-525 (F-SS-1) most effectively inhibited the release of P-hexosamindase from RBL-2H3 cells induced IgE. In IgE-induced RBL-2H3 cells, F-SS-1 inhibited proinflammatory cytokines IL-6 and TNF-alpha mRNA expression. Oral administration of SS-1 and F-SS-1 to mice inhibited passive cutaneous anaphylaxis (PCA) reaction induced by IgE and scratching behaviors induced by compound 48/80. The inhibitory activity of F-SS-1 against scratching behaviors was more effective than that of SS-1. These findings suggest that the fermentation of SS-1 with LAB can increase its antiallergic activity.

  3. INTEGRAL SPI Observations of Cygnus X-1 in the Soft State: What about the Jet Contribution in Hard X-Rays?

    NASA Astrophysics Data System (ADS)

    Jourdain, E.; Roques, J. P.; Chauvin, M.

    2014-07-01

    During the first 7 yr of the INTEGRAL mission (2003-2009), Cyg X-1 has essentially been detected in its hard state (HS), with some incursions in intermediate HSs. This long, spectrally stable period allowed in particular the measurement of the polarization of the high-energy component that has long been observed above 200 keV in this peculiar object. This result strongly suggests that here we see the contribution of the jet, known to emit a strong synchrotron radio emission. In 2010 June, Cyg X-1 underwent a completed transition toward a soft state (SS). It gave us the unique opportunity to study in detail the corona emission in this spectral state, and to investigate in particular the behavior of the jet contribution. Indeed, during the SS, the hard X-ray emission decreases drastically, with its maximum energy shifted toward lower energy and its flux divided by a factor of ~5-10. Interestingly, the radio emission follows a similar drop, supporting the correlation between the jet emission and the hard component, even though the flux is too low to quantify the polarization characteristics. Based on observations with INTEGRAL, an ESA project with instruments and science data center funded by ESA member states (especially the PI countries: Denmark, France, Germany, Italy, Spain, and Switzerland), the Czech Republic and Poland with the participation of Russia and USA.

  4. Radiation from Relativistic Jets

    NASA Technical Reports Server (NTRS)

    Nishikawa, K.-I.; Mizuno, Y.; Hardee, P.; Sol, H.; Medvedev, M.; Zhang, B.; Nordlund, A.; Frederiksen, J. T.; Fishman, G. J.; Preece, R.

    2008-01-01

    Nonthermal radiation observed from astrophysical systems containing relativistic jets and shocks, e.g., gamma-ray bursts (GRBs), active galactic nuclei (AGNs), and Galactic microquasar systems usually have power-law emission spectra. Recent PIC simulations of relativistic electron-ion (electron-positron) jets injected into a stationary medium show that particle acceleration occurs within the downstream jet. In the presence of relativistic jets, instabilities such as the Buneman instability, other two-streaming instability, and the Weibel (filamentation) instability create collisionless shocks, which are responsible for particle (electron, positron, and ion) acceleration. The simulation results show that the Weibel instability is responsible for generating and amplifying highly nonuniform, small-scale magnetic fields. These magnetic fields contribute to the electron's transverse deflection behind the jet head. The 'jitter' radiation from deflected electrons in small-scale magnetic fields has different properties than synchrotron radiation which is calculated in a uniform magnetic field. This jitter radiation, a case of diffusive synchrotron radiation, may be important to understand the complex time evolution and/or spectral structure in gamma-ray bursts, relativistic jets, and supernova remnants.

  5. Mechanisms for RNA capture by ssDNA viruses: grand theft RNA.

    PubMed

    Stedman, Kenneth

    2013-06-01

    Viruses contain three common types of packaged genomes; double-stranded DNA (dsDNA), RNA (mostly single and occasionally double stranded) and single-stranded DNA (ssDNA). There are relatively straightforward explanations for the prevalence of viruses with dsDNA and RNA genomes, but the evolutionary basis for the apparent success of ssDNA viruses is less clear. The recent discovery of four ssDNA virus genomes that appear to have been formed by recombination between co-infecting RNA and ssDNA viruses, together with the high mutation rate of ssDNA viruses provide possible explanations. RNA-DNA recombination allows ssDNA viruses to access much broader sequence space than through nucleotide substitution and DNA-DNA recombination alone. Multiple non-exclusive mechanisms, all due to the unique replication of ssDNA viruses, are proposed for this unusual RNA capture. RNA capture provides an explanation for the evolutionary success of the ssDNA viruses and may help elucidate the mystery of integrated RNA viruses in viral and cellular DNA genomes.

  6. DICHOTOMY OF SOLAR CORONAL JETS: STANDARD JETS AND BLOWOUT JETS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Moore, Ronald L.; Cirtain, Jonathan W.; Sterling, Alphonse C.

    2010-09-01

    By examining many X-ray jets in Hinode/X-Ray Telescope coronal X-ray movies of the polar coronal holes, we found that there is a dichotomy of polar X-ray jets. About two thirds fit the standard reconnection picture for coronal jets, and about one third are another type. We present observations indicating that the non-standard jets are counterparts of erupting-loop H{alpha} macrospicules, jets in which the jet-base magnetic arch undergoes a miniature version of the blowout eruptions that produce major coronal mass ejections. From the coronal X-ray movies we present in detail two typical standard X-ray jets and two typical blowout X-ray jetsmore » that were also caught in He II 304 A snapshots from STEREO/EUVI. The distinguishing features of blowout X-ray jets are (1) X-ray brightening inside the base arch in addition to the outside bright point that standard jets have, (2) blowout eruption of the base arch's core field, often carrying a filament of cool (T {approx} 10{sup 4} - 10{sup 5} K) plasma, and (3) an extra jet-spire strand rooted close to the bright point. We present cartoons showing how reconnection during blowout eruption of the base arch could produce the observed features of blowout X-ray jets. We infer that (1) the standard-jet/blowout-jet dichotomy of coronal jets results from the dichotomy of base arches that do not have and base arches that do have enough shear and twist to erupt open, and (2) there is a large class of spicules that are standard jets and a comparably large class of spicules that are blowout jets.« less

  7. Numerical optimization of a multi-jet cooling system for the blown film extrusion

    NASA Astrophysics Data System (ADS)

    Janas, M.; Wortberg, J.

    2015-05-01

    The limiting factor for every extrusion process is the cooling. For the blown film process, this task is usually done by means of a single or dual lip air ring. Prior work has shown that two major effects are responsible for a bad heat transfer. The first one is the interaction between the jet and the ambient air. It reduces the velocity of the jet and enlarges the straight flow. The other one is the formation of a laminar boundary layer on the film surface due to the fast flowing cooling air. In this case, the boundary layer isolates the film and prevents an efficient heat transfer. To improve the heat exchange, a novel cooling approach is developed, called Multi-Jet. The new cooling system uses several slit nozzles over the whole tube formation zone for cooling the film. In contrast to a conventional system, the cooling air is guided vertically on the film surface in different heights to penetrate the boundary sublayer. Simultaneously, a housing of the tube formation zone is practically obtained to reduce the interaction with the ambient air. For the numerical optimization of the Multi-Jet system, a new procedure is developed. First, a prediction model identifies a worth considering cooling configuration. Therefore, the prediction model computes a film curve using the formulation from Zatloukal-Vlcek and the energy balance for the film temperature. Thereafter, the optimized cooling geometry is investigated in detail using a process model for the blown film extrusion that is able to compute a realistic bubble behavior depending on the cooling situation. In this paper, the Multi-Jet cooling system is numerically optimized for several different process states, like mass throughputs and blow-up ratios using one slit nozzle setting. For each process condition, the best cooling result has to be achieved. Therefore, the height of any nozzle over the tube formation zone is adjustable. The other geometrical parameters of the cooling system like the nozzle diameter or the

  8. Jet in jet in M87

    NASA Astrophysics Data System (ADS)

    Sob'yanin, Denis Nikolaevich

    2017-11-01

    New high-resolution Very Long Baseline Interferometer observations of the prominent jet in the M87 radio galaxy show a persistent triple-ridge structure of the transverse 15-GHz profile with a previously unobserved ultra-narrow central ridge. This radio structure can reflect the intrinsic structure of the jet, so that the jet as a whole consists of two embedded coaxial jets. A relativistic magnetohydrodynamic model is considered in which an inner jet is placed inside a hollow outer jet and the electromagnetic fields, pressures and other physical quantities are found. The entire jet is connected to the central engine that plays the role of a unipolar inductor generating voltage between the jets and providing opposite electric currents, and the charge neutrality and current closure together with the electromagnetic fields between the jets can contribute to the jet stabilization. The constant voltage is responsible for the similar widening laws observed for the inner and outer jets. This jet-in-jet structure can indicate simultaneous operation of two different jet-launching mechanisms, one relating to the central supermassive black hole and the other to the surrounding accretion disc. An inferred magnetic field of 80 G at the base is sufficient to provide the observed jet luminosity.

  9. Novel Immunocytokine IL12-SS1 (Fv) Inhibits Mesothelioma Tumor Growth in Nude Mice

    PubMed Central

    Kim, Heungnam; Gao, Wei; Ho, Mitchell

    2013-01-01

    Mesothelin is a glycosylphosphatidylinositol-anchored glycoprotein that is highly expressed on the cell surface of malignant mesothelioma. Monoclonal antibodies against mesothelin are being evaluated for the treatment of mesothelioma. Immunocytokines represent a novel class of armed antibodies. To provide an alternative approach to current mesothelin-targeted antibody therapies, we have developed a novel immunocytokine based on interleukin-12 (IL12) and the SS1 Fv specific for mesothelin. IL12 possesses potent anti-tumor activity in a wide variety of solid tumors. The newly-developed recombinant immunocytokine, IL12-SS1 (Fv), was produced in insect cells using a baculovirus-insect cell expression system. The SS1 single-chain Fv was fused to the C terminus of the p35 subunit of IL12 through a short linker (GSADGG). The single-chain IL12-SS1 (Fv) immunocytokine bound native mesothelin proteins on malignant mesothelioma (NCI-H226) and ovarian (OVCAR-3) cells as well as recombinant mesothelin on A431/H9 cells. The immunocytokine retained sufficient bioactivity of IL12 and significantly inhibited human malignant mesothelioma (NCI-H226) grown in the peritoneal cavity of nude mice and showed comparable anti-tumor activity to that of the SS1P immunotoxin. IL12-SS1 (Fv) is the first reported immunocytokine to mesothelin-positive tumors and may be an attractive addition to mesothelin-targeted cancer therapies. PMID:24260587

  10. Synthesis and characterization of PEG-P(MAA-SS-VCL) nanoparticles

    NASA Astrophysics Data System (ADS)

    Yu, L. L.; Yang, K.; Mu, R. H.; Zhang, N.; Su, L.

    2016-07-01

    The PEG-P(MAA-SS-VCL) nanoparticles were obtained using disulfide containing dimethacrylate (SS) as cross-linking agent, using polyethylene glycol methyl acrylate (PEGMA), N-Vinyl-ε-caprolactam (VCL), and methacrylic acid (MAA) as monomers via homogeneous polymerization in aqueous. The PEG-P(MAA-SS-VCL) nanoparticles were characterized by FT-IR and TGA. The particle size and morphology variation in different environments were detected by dynamic light scattering (DLS) and scanning electron microscopy (SEM). It is the very method that PEG-P(MAA-SS-VCL) nanoparticles can be obtained in this study.

  11. Computational Analysis of Ares I Roll Control System Jet Interaction Effects on Rolling Moment

    NASA Technical Reports Server (NTRS)

    Deere, Karen A.; Pao, S. Paul; Abdol-Hamid, Khaled S.

    2011-01-01

    The computational flow solver USM3D was used to investigate the jet interaction effects from the roll control system on the rolling moment of the Ares I full protuberance configuration at wind tunnel Reynolds numbers. Solutions were computed at freestream Mach numbers from M = 0.5 to M = 5 at the angle of attack 0deg, at the angle of attack 3.5deg for a roll angle of 120deg, and at the angle of attack 7deg for roll angles of 120deg and 210deg. Results indicate that the RoCS housing provided a beneficial jet interaction effect on vehicle rolling moment for M > or = 0.9. Most of the components downstream of the roll control system housing contributed to jet interaction penalties on vehicle rolling moment.

  12. Parametric effects on pinch-off modes in liquid/liquid jet systems

    NASA Astrophysics Data System (ADS)

    Milosevic, Ilija N.

    Many industries rely on liquid/liquid extraction systems, where jet pinch off occurs on a regular basis. Inherent short time and length scales make analytical and numerical simulation of the process very challenging. A main objective of this work was to document the details of various pinch-off modes at different length scales using Laser Induced Fluorescence and Particle Image Velocimetry. A water glycerine mixture was injected into ambient either silicone oil or 1-octanol. The resultant viscosity ratios, inner to outer fluid, were 1.6 and 2.8, respectively. Ohnesorge numbers were 0.013 for ambient silicone oil and 0.08 for ambient 1-octanol. Reynolds and Strouhal numbers ranged from 30 to 100 and 0.5 to 3.5, respectively. Decreasing the Strouhal number increased the number of drops formed per forcing. Increasing the Reynolds number suppressed satellite formation, and in some cases the number of drops decreased from two to one per cycle. Increasing the Ohnesorge number to 0.08 suppressed the pinch off yielding a longer jet with three-dimensional threads. At Ohnesorge number 0.013, increasing the forcing amplitude shortened the jet, and eventually led to a dripping mode. High-resolution measurements of pinch-off angles were compared to results from similarity theory. Two modes were investigated: drops breaking from the jet (jet/drop) and, one drop splitting into two (splitting drop). The jet/drop mode angle measurements agreed with similarity predictions. The splitting drop mode converged towards smaller angles. Scaling analysis showed that a Stokesian similarity regime applied for a neck radius of 6 microns or less. The smallest radius observed in experiments was 15 microns. Therefore, it is not known whether splitting drop mode might still converge to same behavior.

  13. A thermodynamic analysis of a solar-powered jet refrigeration system

    NASA Technical Reports Server (NTRS)

    Lansing, F. L.; Chai, V. W.

    1980-01-01

    The article describes and analyzes a method of using solar energy to drive a jet refrigeration system. A new technique is presented in the form of a performance nomogram combining the energy and momentum equations to determine the performance characteristics. A numerical example, using water as the working fluid, is given to illustrate the nomogram procedure. The resulting coefficient of performance was found comparable with other refrigeration systems such as the solar-absorption system or the solar-Rankine turbocompressor system.

  14. Vehicle-scale investigation of a fluorine jet-pump liquid hydrogen tank pressurization system

    NASA Technical Reports Server (NTRS)

    Cady, E. C.; Kendle, D. W.

    1972-01-01

    A comprehensive analytical and experimental program was performed to evaluate the performance of a fluorine-hydrogen jet-pump injector for main tank injection (MTI) pressurization of a liquid hydrogen (LH2) tank. The injector performance during pressurization and LH2 expulsion was determined by a series of seven tests of a full-scale injector and MTI pressure control system in a 28.3 cu m (1000 cu ft) flight-weight LH2 tank. Although the injector did not effectively jet-pump LH2 continuously, it showed improved pressurization performance compared to straight-pipe injectors tested under the same conditions in a previous program. The MTI computer code was modified to allow performance prediction for the jet-pump injector.

  15. APOBEC3G Interacts with ssDNA by Two Modes: AFM Studies

    NASA Astrophysics Data System (ADS)

    Shlyakhtenko, Luda S.; Dutta, Samrat; Banga, Jaspreet; Li, Ming; Harris, Reuben S.; Lyubchenko, Yuri L.

    2015-10-01

    APOBEC3G (A3G) protein has antiviral activity against HIV and other pathogenic retroviruses. A3G has two domains: a catalytic C-terminal domain (CTD) that deaminates cytidine, and a N-terminal domain (NTD) that binds to ssDNA. Although abundant information exists about the biological activities of A3G protein, the interplay between sequence specific deaminase activity and A3G binding to ssDNA remains controversial. We used the topographic imaging and force spectroscopy modalities of Atomic Force Spectroscopy (AFM) to characterize the interaction of A3G protein with deaminase specific and nonspecific ssDNA substrates. AFM imaging demonstrated that A3G has elevated affinity for deaminase specific ssDNA than for nonspecific ssDNA. AFM force spectroscopy revealed two distinct binding modes by which A3G interacts with ssDNA. One mode requires sequence specificity, as demonstrated by stronger and more stable complexes with deaminase specific ssDNA than with nonspecific ssDNA. Overall these observations enforce prior studies suggesting that both domains of A3G contribute to the sequence specific binding of ssDNA.

  16. APOBEC3G Interacts with ssDNA by Two Modes: AFM Studies.

    PubMed

    Shlyakhtenko, Luda S; Dutta, Samrat; Banga, Jaspreet; Li, Ming; Harris, Reuben S; Lyubchenko, Yuri L

    2015-10-27

    APOBEC3G (A3G) protein has antiviral activity against HIV and other pathogenic retroviruses. A3G has two domains: a catalytic C-terminal domain (CTD) that deaminates cytidine, and a N-terminal domain (NTD) that binds to ssDNA. Although abundant information exists about the biological activities of A3G protein, the interplay between sequence specific deaminase activity and A3G binding to ssDNA remains controversial. We used the topographic imaging and force spectroscopy modalities of Atomic Force Spectroscopy (AFM) to characterize the interaction of A3G protein with deaminase specific and nonspecific ssDNA substrates. AFM imaging demonstrated that A3G has elevated affinity for deaminase specific ssDNA than for nonspecific ssDNA. AFM force spectroscopy revealed two distinct binding modes by which A3G interacts with ssDNA. One mode requires sequence specificity, as demonstrated by stronger and more stable complexes with deaminase specific ssDNA than with nonspecific ssDNA. Overall these observations enforce prior studies suggesting that both domains of A3G contribute to the sequence specific binding of ssDNA.

  17. APOBEC3G Interacts with ssDNA by Two Modes: AFM Studies

    PubMed Central

    Shlyakhtenko, Luda S.; Dutta, Samrat; Banga, Jaspreet; Li, Ming; Harris, Reuben S.; Lyubchenko, Yuri L.

    2015-01-01

    APOBEC3G (A3G) protein has antiviral activity against HIV and other pathogenic retroviruses. A3G has two domains: a catalytic C-terminal domain (CTD) that deaminates cytidine, and a N-terminal domain (NTD) that binds to ssDNA. Although abundant information exists about the biological activities of A3G protein, the interplay between sequence specific deaminase activity and A3G binding to ssDNA remains controversial. We used the topographic imaging and force spectroscopy modalities of Atomic Force Spectroscopy (AFM) to characterize the interaction of A3G protein with deaminase specific and nonspecific ssDNA substrates. AFM imaging demonstrated that A3G has elevated affinity for deaminase specific ssDNA than for nonspecific ssDNA. AFM force spectroscopy revealed two distinct binding modes by which A3G interacts with ssDNA. One mode requires sequence specificity, as demonstrated by stronger and more stable complexes with deaminase specific ssDNA than with nonspecific ssDNA. Overall these observations enforce prior studies suggesting that both domains of A3G contribute to the sequence specific binding of ssDNA. PMID:26503602

  18. Computational fluid dynamics (CFD) in the design of a water-jet-drive system

    NASA Technical Reports Server (NTRS)

    Garcia, Roberto

    1994-01-01

    NASA/Marshall Space Flight Center (MSFC) has an ongoing effort to transfer to industry the technologies developed at MSFC for rocket propulsion systems. The Technology Utilization (TU) Office at MSFC promotes these efforts and accepts requests for assistance from industry. One such solicitation involves a request from North American Marine Jet, Inc. (NAMJ) for assistance in the design of a water-jet-drive system to fill a gap in NAMJ's product line. NAMJ provided MSFC with a baseline axial flow impeller design as well as the relevant working parameters (rpm, flow rate, etc.). This baseline design was analyzed using CFD, and significant deficiencies identified. Four additional analyses were performed involving MSFC changes to the geometric and operational parameters of the baseline case. Subsequently, the impeller was redesigned by NAMJ and analyzed by MSFC. This new configuration performs significantly better than the baseline design. Similar cooperative activities are planned for the design of the jet-drive inlet.

  19. A preliminary study of a new endodontic irrigation system: Clean Jet Endo.

    PubMed

    Nouioua, F; Slimani, A; Levallois, B; Camps, J; Tassery, H; Cuisinier, F; Bukiet, F

    2015-03-01

    The purpose of the present study was to assess the irrigant penetration and cleaning ability of a new irrigation system, the Clean Jet Endo (Produits Dentaires SA, Switzerland) in comparison to conventional irrigation followed or not by sonic activation. Irrigant penetration was evaluated on resin blocks simulators by measuring the methylene blue absorbance thanks to a UV/visible spectrophotometer and cleaning ability was assessed in an ex vivo experiment according to the debris score in an artificial canal extension before and after the final irrigation protocol. A statistical analysis was carried out in order to highlight the significant differences between the irrigation techniques. Clean Jet Endo permitted to better eliminate the methylene blue into the simulated canals. A significant difference between the 2 techniques was observed in the middle third (p = 0.005) as well as in the apical third (p < 0.2). An additional microscope observation (16X) confirmed that Clean Jet Endo@ usage led to a better penetration of irrigant within the lateral canals of the simulators. Likewise, this irrigating system permitted to better eliminate the debris in the lateral groove than the other techniques. In conclusion, our findings implied the potential of this new irrigation system to enhance root canal debridement and disinfection.

  20. Design, Fabrication, and Testing of an Auxiliary Cooling System for Jet Engines

    NASA Technical Reports Server (NTRS)

    Leamy, Kevin; Griffiths, Jim; Andersen, Paul; Joco, Fidel; Laski, Mark; Balser, Jeffrey (Technical Monitor)

    2001-01-01

    This report summarizes the technical effort of the Active Cooling for Enhanced Performance (ACEP) program sponsored by NASA. It covers the design, fabrication, and integrated systems testing of a jet engine auxiliary cooling system, or turbocooler, that significantly extends the use of conventional jet fuel as a heat sink. The turbocooler is designed to provide subcooled cooling air to the engine exhaust nozzle system or engine hot section. The turbocooler consists of three primary components: (1) a high-temperature air cycle machine driven by engine compressor discharge air, (2) a fuel/ air heat exchanger that transfers energy from the hot air to the fuel and uses a coating to mitigate fuel deposits, and (3) a high-temperature fuel injection system. The details of the turbocooler component designs and results of the integrated systems testing are documented. Industry Version-Data and information deemed subject to Limited Rights restrictions are omitted from this document.

  1. Structure/property (constitutive and dynamic strength/damage) characterization of additively manufactured 316L SS

    NASA Astrophysics Data System (ADS)

    Gray, G. T., III; Livescu, V.; Rigg, P. A.; Trujillo, C. P.; Cady, C. M.; Chen, S. R.; Carpenter, J. S.; Lienert, T. J.; Fensin, S.

    2015-09-01

    For additive manufacturing (AM), the certification and qualification paradigm needs to evolve as there exists no "ASTM-type" additive manufacturing certified process or AM-material produced specifications. Accordingly, utilization of AM materials to meet engineering applications requires quantification of the constitutive properties of these evolving materials in comparison to conventionally-manufactured metals and alloys. Cylinders of 316L SS were produced using a LENS MR-7 laser additive manufacturing system from Optomec (Albuquerque, NM) equipped with a 1kW Yb-fiber laser. The microstructure of the AM-316L SS is detailed in both the as-built condition and following heat-treatments designed to obtain full recrystallization. The constitutive behavior as a function of strain rate and temperature is presented and compared to that of nominal annealed wrought 316L SS plate. The dynamic damage evolution and failure response of all three materials was probed using flyer-plate impact driven spallation experiments at a peak stress of 4.5 GPa to examine incipient spallation response. The spall strength of AM-produced 316L SS was found to be very similar for the peak shock stress studied to that of annealed wrought or AM-316L SS following recrystallization. The damage evolution as a function of microstructure was characterized using optical metallography.

  2. SS 383: A NEW S-TYPE YELLOW SYMBIOTIC STAR?

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Baella, N. O.; Pereira, C. B.; Miranda, L. F.

    Symbiotic stars are key objects in understanding the formation and evolution of interacting binary systems, and are probably the progenitors of Type Ia supernovae. However, the number of known symbiotic stars is much lower than predicted. We aim to search for new symbiotic stars, with particular emphasis on the S-type yellow symbiotic stars, in order to determine their total population, evolutionary timescales, and physical properties. The Two Micron All Sky Survey (2MASS) (J – H) versus (H – K {sub s}) color-color diagram has been previously used to identify new symbiotic star candidates and show that yellow symbiotics are locatedmore » in a particular region of that diagram. Candidate symbiotic stars are selected on the basis of their locus in the 2MASS (J – H) versus (H – K {sub s}) diagram and the presence of Hα line emission in the Stephenson and Sanduleak Hα survey. This diagram separates S-type yellow symbiotic stars from the rest of the S-type symbiotic stars, allowing us to select candidate yellow symbiotics. To establish the true nature of the candidates, intermediate-resolution spectroscopy is obtained. We have identified the Hα emission line source SS 383 as an S-type yellow symbiotic candidate by its position in the 2MASS color-color diagram. The optical spectrum of SS 383 shows Balmer, He I, He II, and [O III] emission lines, in combination with TiO absorption bands that confirm its symbiotic nature. The derived electron density (≅10{sup 8-9} cm{sup –3}), He I emission line intensity ratios, and position in the [O III] λ5007/Hβ versus [O III] λ4363/Hγ diagram indicate that SS 383 is an S-type symbiotic star, with a probable spectral type of K7-M0 deduced for its cool component based on TiO indices. The spectral type and the position of SS 383 (corrected for reddening) in the 2MASS color-color diagram strongly suggest that SS 383 is an S-type yellow symbiotic. Our result points out that the 2MASS color-color diagram is a powerful

  3. The near infrared imaging system for the real-time protection of the JET ITER-like wall

    NASA Astrophysics Data System (ADS)

    Huber, A.; Kinna, D.; Huber, V.; Arnoux, G.; Balboa, I.; Balorin, C.; Carman, P.; Carvalho, P.; Collins, S.; Conway, N.; McCullen, P.; Jachmich, S.; Jouve, M.; Linsmeier, Ch; Lomanowski, B.; Lomas, P. J.; Lowry, C. G.; Maggi, C. F.; Matthews, G. F.; May-Smith, T.; Meigs, A.; Mertens, Ph; Nunes, I.; Price, M.; Puglia, P.; Riccardo, V.; Rimini, F. G.; Sergienko, G.; Tsalas, M.; Zastrow, K.-D.; contributors, JET

    2017-12-01

    This paper describes the design, implementation and operation of the near infrared (NIR) imaging diagnostic system of the JET ITER-like wall (JET-ILW) plasma experiment and its integration into the existing JET protection architecture. The imaging system comprises four wide-angle views, four tangential divertor views, and two top views of the divertor covering 66% of the first wall and up to 43% of the divertor. The operation temperature ranges which must be observed by the NIR protection cameras are, for the materials used on JET: Be 700 °C-1400 °C W coating 700 °C-1370 °C W bulk 700 °C-1400 °C. The Real-Time Protection system operates routinely since 2011 and successfully demonstrated its capability to avoid the overheating of the main chamber beryllium wall as well as of the divertor W and W-coated carbon fibre composite (CFC) tiles. During this period, less than 0.5% of the terminated discharges were aborted by a malfunction of the system. About 2%-3% of the discharges were terminated due to the detection of actual hot spots.

  4. Free compressible jet investigation

    NASA Astrophysics Data System (ADS)

    De Gregorio, Fabrizio

    2014-03-01

    The nozzle pressure ratio (NPR) effect on a supersonic turbulent jet was investigated. A dedicated convergent/divergent nozzle together with a flow feeding system was designed and manufactured. A nozzle Mach exit of M j = 1.5 was selected in order to obtain a convective Mach number of M c = 0.6. The flow was investigated for over-expanded, correctly expanded and under-expanded jet conditions. Mach number, total temperature and flow velocity measurements were carried out in order to characterise the jet behaviour. The inlet conditions of the jet flow were monitored in order to calculate the nozzle exit speed of sound and evaluate the mean Mach number distribution starting from the flow velocity data. A detailed analysis of the Mach results obtained by a static Pitot probe and by a particle image velocimetry measurement system was carried out. The mean flow velocity was investigated, and the axial Mach decay and the spreading rate were associated with the flow structures and with the compressibility effects. Aerodynamics of the different jet conditions was evaluated, and the shock cells structures were detected and discussed correlating the jet structure to the flow fluctuation and local turbulence. The longitudinal and radial distribution of the total temperature was investigated, and the temperature profiles were analysed and discussed. The total temperature behaviour was correlated to the turbulent phenomena and to the NPR jet conditions. Self-similarity condition was encountered and discussed for the over-expanded jet. Compressibility effects on the local turbulence, on the turbulent kinetic energy and on the Reynolds tensor were discussed.

  5. Real-Time Processing System for the JET Hard X-Ray and Gamma-Ray Profile Monitor Enhancement

    NASA Astrophysics Data System (ADS)

    Fernandes, Ana M.; Pereira, Rita C.; Neto, André; Valcárcel, Daniel F.; Alves, Diogo; Sousa, Jorge; Carvalho, Bernardo B.; Kiptily, Vasily; Syme, Brian; Blanchard, Patrick; Murari, Andrea; Correia, Carlos M. B. A.; Varandas, Carlos A. F.; Gonçalves, Bruno

    2014-06-01

    The Joint European Torus (JET) is currently undertaking an enhancement program which includes tests of relevant diagnostics with real-time processing capabilities for the International Thermonuclear Experimental Reactor (ITER). Accordingly, a new real-time processing system was developed and installed at JET for the gamma-ray and hard X-ray profile monitor diagnostic. The new system is connected to 19 CsI(Tl) photodiodes in order to obtain the line-integrated profiles of the gamma-ray and hard X-ray emissions. Moreover, it was designed to overcome the former data acquisition (DAQ) limitations while exploiting the required real-time features. The new DAQ hardware, based on the Advanced Telecommunication Computer Architecture (ATCA) standard, includes reconfigurable digitizer modules with embedded field-programmable gate array (FPGA) devices capable of acquiring and simultaneously processing data in real-time from the 19 detectors. A suitable algorithm was developed and implemented in the FPGAs, which are able to deliver the corresponding energy of the acquired pulses. The processed data is sent periodically, during the discharge, through the JET real-time network and stored in the JET scientific databases at the end of the pulse. The interface between the ATCA digitizers, the JET control and data acquisition system (CODAS), and the JET real-time network is provided by the Multithreaded Application Real-Time executor (MARTe). The work developed allowed attaining two of the major milestones required by next fusion devices: the ability to process and simultaneously supply high volume data rates in real-time.

  6. The Discovery of a Disk-Jet System Directly Exposed to Strong Ultraviolet Fields in the Rosette Nebula

    NASA Astrophysics Data System (ADS)

    Li, Jin Zeng; Rector, Travis A.

    2004-01-01

    We report on the discovery of an optical jet with a striking morphology in the Rosette Nebula. It could be the most extreme case known of an accretion disk and jet system directly exposed to strong ionization fields that impose strong effects on disk evolution. Unlike typical optical flows, this jet system is found to have a high excitation nature mainly due to disruptive interaction with the violent environment. As a result, the extension of the highly collimated jet and possible former episodes of the degenerated counterjet all show bow-shocked structures. Our results provide implications on how incipience of massive stars in giant molecular clouds prevents further generations of low-mass star formation, and possibly also how isolated substellar/planetary-mass objects in regions of massive star formation are formed.

  7. Controllable g5p-Protein-Directed Aggregation of ssDNA-Gold Nanoparticles

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lee, S.; Maye, M; Zhang, Y

    We assembled single-stranded DNA (ssDNA) conjugated nanoparticles using the phage M13 gene 5 protein (g5p) as the molecular glue to bind two antiparallel noncomplementary ssDNA strands. The entire process was controlled tightly by the concentration of the g5p protein and the presence of double-stranded DNA. The g5p-ssDNA aggregate was disintegrated by hybridization with complementary ssDNA (C-ssDNA) that triggers the dissociation of the complex. Polyhistidine-tagged g5p was bound to nickel nitrilotriacetic acid (Ni2+-NTA) conjugated nanoparticles and subsequently used to coassemble the ssDNA-conjugated nanoparticles into multiparticle-type aggregates. Our approach offers great promise for designing biologically functional, controllable protein/nanoparticle composites.

  8. Submerged jet mixing in nuclear waste tanks: a correlation for jet velocity

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Daas, M.; Srivastava, R.; Roelant, D.

    2007-07-01

    Experimental studies were carried out in jet-stirred slurry tanks to correlate the influence of nozzle diameter, initial jet flow velocity, submerged depth of jet, tank diameter and slurry properties on the jet axial velocity. The tanks used in the experimental work had diameters of 0.3 m (1-ft) and 2.13 m (7-ft). The fluids emerged from nozzles of 0.003 m and 0.01 m in diameter, 1/8-inch and 3/8-inch respectively. The examined slurries were non-Newtonian and contained 5 weight percent total insoluble solids. The axial velocities along the centerline of a submerged jet stream were measured at different jet flow rates andmore » at various distances from the nozzle orifice (16 to 200 nozzle diameters) utilizing electromagnetic velocity meter. A new simplified correlation was developed to describe the jet axial velocity in submerged jet stirred tanks utilizing more than 350 data points. The Buckingham Pi theorem and non-linear regression method of multivariate approximation, in conjunction with the Gauss-Jordan elimination method, were used to develop the new correlation. The new correlation agreed well with the experimental data obtained from the current study. Good agreement was also possible with literature data except at large distances from the nozzle as the model slightly overestimated the jet axial velocity. The proposed correlation incorporates the contributions of system geometry, fluid properties, and external forces. Furthermore, it provides reasonable estimates of jet axial velocity. (authors)« less

  9. The jet-disk symbiosis without maximal jets: 1D hydrodynamical jets revisited

    NASA Astrophysics Data System (ADS)

    Crumley, Patrick; Ceccobello, Chiara; Connors, Riley M. T.; Cavecchi, Yuri

    2017-05-01

    In this work we discuss the recent criticism by Zdziarski (2016, A&A, 586, A18) of the maximal jet model derived in Falcke & Biermann (1995, A&A, 293, 665). We agree with Zdziarski that in general a jet's internal energy is not bounded by its rest-mass energy density. We describe the effects of the mistake on conclusions that have been made using the maximal jet model and show when a maximal jet is an appropriate assumption. The maximal jet model was used to derive a 1D hydrodynamical model of jets in agnjet, a model that does multiwavelength fitting of quiescent/hard state X-ray binaries and low-luminosity active galactic nuclei. We correct algebraic mistakes made in the derivation of the 1D Euler equation and relax the maximal jet assumption. We show that the corrections cause minor differences as long as the jet has a small opening angle and a small terminal Lorentz factor. We find that the major conclusion from the maximal jet model, the jet-disk symbiosis, can be generally applied to astrophysical jets. We also show that isothermal jets are required to match the flat radio spectra seen in low-luminosity X-ray binaries and active galactic nuclei, in agreement with other works.

  10. Self-similar semi-analytical RMHD jet model: first steps towards a more comprehensive jet modelling for data fitting

    NASA Astrophysics Data System (ADS)

    Markoff, Sera; Ceccobello, Chiara; Heemskerk, Martin; Cavecchi, Yuri; Polko, Peter; Meier, David

    2017-08-01

    Jets are ubiquitous and reveal themselves at different scales and redshifts, showing an extreme diversity in energetics, shapes and emission. Indeed jets are found to be characteristic features of black hole systems, such as X-ray binaries (XRBs) and active galactic nuclei (AGN), as well as of young stellar objects (YSOs) and gamma-ray bursts (GRBs). Observations suggest that jets are an energetically important component of the system that hosts them, because the jet power appears to be comparable to the accretion power. Significant evidence has been found of the impact of jets not only in the immediate proximity of the central object, but as well on their surrounding environment, where they deposit the energy extracted from the accretion flow. Moreover, the inflow/outflow system produces radiation over the entire electromagnetic spectrum, from radio to X-rays. Therefore it is a compelling problem to be solved and deeply understood. I present a new integration scheme to solve radial self-similar, stationary, axisymmetric relativistic magneto-hydro-dynamics (MHD) equations describing collimated, relativistic outflows crossing smoothly all the singular points (the Alfvén point and the modified slow/fast points). For the first time, the integration can be performed all the way from the disk mid-plane to downstream of the modified fast point. I will discuss an ensemble of jet solutions showing diverse jet dynamics (jet Lorentz factor ~ 1-10) and geometric properties (i.e. shock height ~ 103 - 107 gravitational radii), which makes our model suitable for application to many different systems where a relativistic jet is launched.

  11. Redox-sensitive micelles assembled from amphiphilic mPEG-PCL-SS-DTX conjugates for the delivery of docetaxel.

    PubMed

    Zhang, Huiyuan; Wang, Kaiming; Zhang, Pei; He, Wenxiu; Song, Aixin; Luan, Yuxia

    2016-06-01

    Docetaxel (DTX) can produce anti-tumor effects by inhibiting cell growth and inducing apoptosis. However, the poor solubility of DTX restricts its application and its clinical formulation has caused serious adverse reaction due to the use of Tween-80. In the present study, DTX was conjugated to an amphiphilic di-block polymer to solve these problems. Methoxy poly(ethylene glycol)-poly(ε-caprolactone) (mPEG-PCL) was selected as the polymer skeleton and a redox sensitive disulfide bond was used as the linker between DTX and mPEG-PCL. The synthesized mPEG-PCL-SS-DTX conjugates were characterized by (1)H-nuclear magnetic resonance ((1)H NMR) and Fourier transform infrared spectroscopy (FTIR). Interestingly, the mPEG-PCL-SS-DTX conjugates could self-assemble into micelles in aqueous solution. The critical micelle concentration (CMC) of mPEG-PCL-SS-DTX micelles was about 2.3mgL(-1) determined using pyrene molecule fluorescent probe method while the size of mPEG-PCL-SS-DTX micelles was determined to be ca. 17.6nm and 116.0nm with a bimodal distribution by dynamic light scattering (DLS). The in vitro release results indicated that the as-prepared micelles exhibited a sustained release profile with good redox sensitive properties. In particular, the hemolytic toxicity test indicated the as-prepared mPEG-PCL-SS-DTX micelles had negligible hemolytic activity, demonstrating their safety in drug delivery system. Cytotoxicity assay of the mPEG-PCL-SS-DTX micelles verified their highly enhanced cytotoxicity to MCF-7/A and A549 cells. These results thus demonstrated that the present redox-sensitive mPEG-PCL-SS-DTX micelle was an efficient and safe sustained drug delivery system in the biomedical area. Copyright © 2016 Elsevier B.V. All rights reserved.

  12. Pinching solutions of slender cylindrical jets

    NASA Technical Reports Server (NTRS)

    Papageorgiou, Demetrios T.; Orellana, Oscar

    1993-01-01

    Simplified equations for slender jets are derived for a circular jet of one fluid flowing into an ambient second fluid, the flow being confined in a circular tank. Inviscid flows are studied which include both surface tension effects and Kelvin-Helmholtz instability. For slender jets a coupled nonlinear system of equations is found for the jet shape and the axial velocity jump across it. The equations can break down after a finite time and similarity solutions are constructed, and studied analytically and numerically. The break-ups found pertain to the jet pinching after a finite time, without violation of the slender jet ansatz. The system is conservative and admissible singular solutions are those which conserve the total energy, mass, and momentum. Such solutions are constructed analytically and numerically, and in the case of vortex sheets with no surface tension certain solutions are given in closed form.

  13. An arc control and protection system for the JET lower hybrid antenna based on an imaging system

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Figueiredo, J., E-mail: joao.figueiredo@jet.efda.org; Mailloux, J.; Kirov, K.

    Arcs are the potentially most dangerous events related to Lower Hybrid (LH) antenna operation. If left uncontrolled they can produce damage and cause plasma disruption by impurity influx. To address this issue an arc real time control and protection imaging system for the Joint European Torus (JET) LH antenna has been implemented. The LH system is one of the additional heating systems at JET. It comprises 24 microwave generators (klystrons, operating at 3.7 GHz) providing up to 5 MW of heating and current drive to the JET plasma. This is done through an antenna composed of an array of waveguidesmore » facing the plasma. The protection system presented here is based primarily on an imaging arc detection and real time control system. It has adapted the ITER like wall hotspot protection system using an identical CCD camera and real time image processing unit. A filter has been installed to avoid saturation and spurious system triggers caused by ionization light. The antenna is divided in 24 Regions Of Interest (ROIs) each one corresponding to one klystron. If an arc precursor is detected in a ROI, power is reduced locally with subsequent potential damage and plasma disruption avoided. The power is subsequently reinstated if, during a defined interval of time, arcing is confirmed not to be present by image analysis. This system was successfully commissioned during the restart phase and beginning of the 2013 scientific campaign. Since its installation and commissioning, arcs and related phenomena have been prevented. In this contribution we briefly describe the camera, image processing, and real time control systems. Most importantly, we demonstrate that an LH antenna arc protection system based on CCD camera imaging systems works. Examples of both controlled and uncontrolled LH arc events and their consequences are shown.« less

  14. An arc control and protection system for the JET lower hybrid antenna based on an imaging system.

    PubMed

    Figueiredo, J; Mailloux, J; Kirov, K; Kinna, D; Stamp, M; Devaux, S; Arnoux, G; Edwards, J S; Stephen, A V; McCullen, P; Hogben, C

    2014-11-01

    Arcs are the potentially most dangerous events related to Lower Hybrid (LH) antenna operation. If left uncontrolled they can produce damage and cause plasma disruption by impurity influx. To address this issue an arc real time control and protection imaging system for the Joint European Torus (JET) LH antenna has been implemented. The LH system is one of the additional heating systems at JET. It comprises 24 microwave generators (klystrons, operating at 3.7 GHz) providing up to 5 MW of heating and current drive to the JET plasma. This is done through an antenna composed of an array of waveguides facing the plasma. The protection system presented here is based primarily on an imaging arc detection and real time control system. It has adapted the ITER like wall hotspot protection system using an identical CCD camera and real time image processing unit. A filter has been installed to avoid saturation and spurious system triggers caused by ionization light. The antenna is divided in 24 Regions Of Interest (ROIs) each one corresponding to one klystron. If an arc precursor is detected in a ROI, power is reduced locally with subsequent potential damage and plasma disruption avoided. The power is subsequently reinstated if, during a defined interval of time, arcing is confirmed not to be present by image analysis. This system was successfully commissioned during the restart phase and beginning of the 2013 scientific campaign. Since its installation and commissioning, arcs and related phenomena have been prevented. In this contribution we briefly describe the camera, image processing, and real time control systems. Most importantly, we demonstrate that an LH antenna arc protection system based on CCD camera imaging systems works. Examples of both controlled and uncontrolled LH arc events and their consequences are shown.

  15. Investigation of blown boundary layers with an improved wall jet system

    NASA Technical Reports Server (NTRS)

    Saripalli, K. R.; Simpson, R. L.

    1980-01-01

    Measurements were made in a two dimensional incompressible wall jet submerged under a thick upstream boundary layer with a zero pressure gradient and an adverse pressure gradient. The measurements included mean velocity and Reynolds stresses profiles, skin friction, and turbulence spectra. The measurements were confined to practical ratios (less than 2) of the jet velocity to the free stream velocity. The wall jet used in the experiments had an asymmetric velocity profile with a relatively higher concentration of momentum away from the wall. An asymmetric jet velocity profile has distinct advantages over a uniform jet velocity profile, especially in the control of separation. Predictions were made using Irwin's (1974) method for blown boundary layers. The predictions clearly show the difference in flow development between an asymmetric jet velocity profile and a uniform jet velocity profile.

  16. Loop system for creating jet fuel vapor standards used in the calibration of infrared spectrophotometers and gas chromatographs.

    PubMed

    Reboulet, James; Cunningham, Robert; Gunasekar, Palur G; Chapman, Gail D; Stevens, Sean C

    2009-02-01

    A whole body inhalation study of mixed jet fuel vapor and its aerosol necessitated the development of a method for preparing vapor only standards from the neat fuel. Jet fuel is a complex mixture of components which partitions between aerosol and vapor when aspirated based on relative volatility of the individual compounds. A method was desired which could separate the vapor portion from the aerosol component to prepare standards for the calibration of infrared spectrophotometers and a head space gas chromatography system. A re-circulating loop system was developed which provided vapor only standards whose composition matched those seen in an exposure system. Comparisons of nominal concentrations in the exposure system to those determined by infrared spectrophotometry were in 92-95% agreement. Comparison of jet fuel vapor concentrations determined by infrared spectrophotometry compared to head space gas chromatography yielded a 93% overall agreement in trial runs. These levels of agreement show the loop system to be a viable method for creating jet fuel vapor standards for calibrating instruments.

  17. Description of Jet Breakup

    NASA Technical Reports Server (NTRS)

    Papageorgiou, Demetrios T.

    1996-01-01

    In this article we review recent results on the breakup of cylindrical jets of a Newtonian fluid. Capillary forces provide the main driving mechanism and our interest is in the description of the flow as the jet pinches to form drops. The approach is to describe such topological singularities by constructing local (in time and space) similarity solutions from the governing equations. This is described for breakup according to the Euler, Stokes or Navier-Stokes equations. It is found that slender jet theories can be applied when viscosity is present, but for inviscid jets the local shape of the jet at breakup is most likely of a non-slender geometry. Systems of one-dimensional models of the governing equations are solved numerically in order to illustrate these differences.

  18. Clinical characteristics of RA patients with secondary SS and association with joint damage.

    PubMed

    Brown, Lindsay E; Frits, Michelle L; Iannaccone, Christine K; Weinblatt, Michael E; Shadick, Nancy A; Liao, Katherine P

    2015-05-01

    Secondary SS (sSS) is a common extra-articular manifestation of RA. There are conflicting data regarding the association of sSS with worse joint damage. This study aims to characterize sSS patients in an RA cohort and study the association between sSS and joint damage. We conducted a cross-sectional study of RA patients with ≥1 year of follow-up at a large academic centre. Subjects with co-morbid diseases that can also result in sicca symptoms were excluded from the analysis. Subjects were considered to have sSS if they were reported as having sSS by their rheumatologist at recruitment into the cohort and had the diagnosis confirmed by chart review. The primary outcome was Sharp score using bilateral hand radiographs at recruitment. We constructed a linear regression model to determine the association of sSS status and Sharp score adjusted by age, gender, disease duration and ACPA and RF status. We studied 829 RA subjects, mean age 57 years, 83% female, mean RA duration 13 years, 74% seropositive; 85 subjects (10.3%) had sSS. We observed a female predominance (95.3%), longer mean disease duration (16.9 years) and higher frequency of RF or ACPA positive among patients with sSS and RA. Having sSS at baseline was associated with higher Sharp scores (P = 0.03), independent of age, gender, RA disease duration and seropositive disease. In our RA cohort, RA subjects with sSS had worse joint damage, suggesting that sSS is a marker of more aggressive disease. © The Author 2014. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  19. Network Management and FDIR for SpaceWire Networks (N-MaSS)

    NASA Astrophysics Data System (ADS)

    Montano, Giuseppe; Jameux, David; Cook, Barry; Peel, Rodger; McCormick, Ecaterina; Walker, Paul; Kollias, Vangelis; Pogkas, Nikos

    2014-08-01

    The SpaceWire network management layer, which manages network topology and routing, is not yet standardised. This paper presents the European Space Agency (ESA) N-MaSS study, which focuses on implementation and standardisation of Fault Detection, Isolation and Recovery (FDIR) functions within the SpaceWire network management layer. N-MaSS provides an autonomous FDIR solution. It is defined at the SpaceWire network layer in order to achieve efficient re-use for heterogeneous missions, allowing for the incorporation of legacy equipment. The N-MaSS FDIR functions identify SpaceWire link and node failures and provide recovery using redundant nodes.This paper provides an overview of the overall N- MaSS study. In particular, the following topics are discussed: (a) how user requirements have been captured from the industry, SpaceWire Working Group and ESA; (b) how the N-MaSS architecture was organically shaped on the basis of the requirements captured; (c) how the N-MaSS concept is currently being implemented in a demonstrator and verified.

  20. The KIzSS network, a sentinel surveillance system for infectious diseases in day care centers: study protocol.

    PubMed

    Enserink, Remko; Noel, Harold; Friesema, Ingrid H M; de Jager, Carolien M; Kooistra-Smid, Anna M D; Kortbeek, Laetitia M; Duizer, Erwin; van der Sande, Marianne A B; Smit, Henriette A; Pelt, Wilfrid van

    2012-10-15

    Day care-associated infectious diseases are widely recognized as a public health problem but rarely studied. Insights into their dynamics and their association with the day care setting are important for effective decision making in management of infectious disease control. This paper describes the purpose, design and potential of our national multi-center, day care-based sentinel surveillance network for infectious diseases (the KIzSS network). The aim of the KIzSS network is to acquire a long-term insight into the syndromic and microbiological aspects of day care-related infectious diseases and associated disease burden and to model these aspects with day care setting characteristics. The KIzSS network applies a prospective cohort design, following day care centers rather than individual children or staff members over time. Data on infectious disease symptoms and related morbidity (children and staff), medical consumption, absenteeism and circulating enteric pathogens (children) are collected on a daily, weekly or monthly basis. Every two years, a survey is performed to assess the characteristics of participating day care centers. The KIzSS network offers a unique potential to study infectious disease dynamics in the day care setting over a sustained period of time. The created (bio)databases will help us to assess day care-related disease burden of infectious diseases among attending children and staff and their relation with the day care setting. This will support the much needed development of evidence-based and pragmatic guidelines for infectious disease control in day care centers.

  1. 21 CFR 876.4650 - Water jet renal stone dislodger system.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... dislodge stones from renal calyces (recesses of the pelvis of the kidney) by means of a pressurized stream of water through a conduit. The device is used in the surgical removal of kidney stones. (b... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Water jet renal stone dislodger system. 876.4650...

  2. 21 CFR 876.4650 - Water jet renal stone dislodger system.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... dislodge stones from renal calyces (recesses of the pelvis of the kidney) by means of a pressurized stream of water through a conduit. The device is used in the surgical removal of kidney stones. (b... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Water jet renal stone dislodger system. 876.4650...

  3. Aerodynamic Interactions of Propulsive Deceleration and Reaction Control System Jets on Mars-Entry Aeroshells

    NASA Astrophysics Data System (ADS)

    Alkandry, Hicham

    Future missions to Mars, including sample-return and human-exploration missions, may require alternative entry, descent, and landing technologies in order to perform pinpoint landing of heavy vehicles. Two such alternatives are propulsive deceleration (PD) and reaction control systems (RCS). PD can slow the vehicle during Mars atmospheric descent by directing thrusters into the incoming freestream. RCS can provide vehicle control and steering by inducing moments using thrusters on the hack of the entry capsule. The use of these PD and RCS jets, however, involves complex flow interactions that are still not well understood. The fluid interactions induced by PD and RCS jets for Mars-entry vehicles in hypersonic freestream conditions are investigated using computational fluid dynamics (CFD). The effects of central and peripheral PD configurations using both sonic and supersonic jets at various thrust conditions are examined in this dissertation. The RCS jet is directed either parallel or transverse to the freestream flow at different thrust conditions in order to examine the effects of the thruster orientation with respect to the center of gravity of the aeroshell. The physical accuracy of the computational method is also assessed by comparing the numerical results with available experimental data. The central PD configuration decreases the drag force acting on the entry capsule due to a shielding effect that prevents mass and momentum in the hypersonic freestream from reaching the aeroshell. The peripheral PD configuration also decreases the drag force by obstructing the flow around the aeroshell and creating low surface pressure regions downstream of the PD nozzles. The Mach number of the PD jets, however, does not have a significant effect on the induced fluid interactions. The reaction control system also alters the flowfield, surface, and aerodynamic properties of the aeroshell, while the jet orientation can have a significant effect on the control effectiveness

  4. Vapor condensation on liquid surface due to laminar jet-induced mixing: The effects of system parameters

    NASA Technical Reports Server (NTRS)

    Lin, Chin-Shun; Hasan, Mohammad M.

    1989-01-01

    The effects of system parameters on the interface condensation rate in a laminar jet induced mixing tank are numerically studied. The physical system consists of a partially filled cylindrical tank with a slightly subcooled jet discharged from the center of the tank bottom toward the liquid-vapor interface which is at a saturation temperature corresponding to the constant tank pressure. Liquid is also withdrawn from the outer part of the tank bottom to maintain the constant liquid level. The jet velocity is selected to be low enough such that the free surface is approximately flat. The effect of vapor superheat is assumed to be negligible. Therefore, the interface condensation rate can be determined from the resulting temperature field in the liquid region alone. The nondimensional form of the steady state conservation equations are solved by a finite difference method for various system parameters including liquid height to tank diameter ratio, tank to jet diameter ratio, liquid inflow to outflow area ratio, and a heat leak parameter which characterizes the uniform wall heat flux. Detailed analyses based on the numerical solutions are performed and simplified equations are suggested for the prediction of condensation rate.

  5. Symbolic and Sub-Symbolic Robotic Intelligence Control System (SS-RICS) Users Manual

    DTIC Science & Technology

    2017-10-01

    platform and simulators via either a serial or Transmission Control Protocol (TCP)/IP connection. The implementation of SS-RICS was designed and...box 4.2 SubSim Config Dialog This interface (Fig. 22) is designed to provide execution and property control of all of the subsimprocessors... post fixed with a “_” to designate the end of the variable (e.g., $Line1_memory was found). Example: rTestDollarSign { (* $LookType Distance

  6. Research on thermal protection mechanism of forward-facing cavity and opposing jet combinatorial thermal protection system

    NASA Astrophysics Data System (ADS)

    Lu, Hai-Bo; Liu, Wei-Qiang

    2014-04-01

    Validated by the correlated experiments, a nose-tip with forward-facing cavity/opposing jet/the combinatorial configuration of forward-facing cavity and opposing jet thermal protection system (TPS) are investigated numerically. The physical mechanism of these TPS is discussed, and the cooling efficiency of them is compared. The combinatorial system is more suitable to be the TPS for the high speed vehicles which need fly under various flow conditions with long-range and long time.

  7. Stanford SsTO Mission to Mars: A Realistic, Safe and Cost Effective Approach to Human Mars Exploration Using the Stanford SsTO Launch System

    NASA Astrophysics Data System (ADS)

    Osborne, Robert D.

    1999-06-01

    In recent years, a lot of time and energy has been spent exploring possible mission scenarios for a human mission to Mars. NASA along with the privately funded Mars Society and a number of universities have come up with many options that could place people on the surface of Mars in a relatively short period of time at a relatively low cost. However, a common theme among all or at least most of these missions is that they require heavy lift vehicles such as the Russian Energia or the NASA proposed Magnum 100MT class vehicle to transport large payloads from the surface of Earth into a staging orbit about Earth. However, there is no current budget or any signs for a future budget to review the Russian Energia, the US made Saturn V, or to design and build a new heavy lift vehicle. However, there is a lot of interest and many companies looking into the possibility of "space planes". These vehicles will have the capability to place a payload into orbit without throwing any parts of the vehicle away. The concept of a space plane is basically that the plane is transported to a given altitude either by it's own power or on the back of another air worthy vehicle before the rocket engines are ignited. From this altitude, a Single Step to Orbit (SsTO) vehicle with a significant payload is possible. This report looks at the possibility of removing the requirement of a heavy lift vehicle by using the Stanford designed Single Step to Orbit.(SsTO) Launch Vehicle. The SsTO would eliminate the need for heavy lift vehicles and actually reduce the cost of the mission because of the very low costs involved with each SSTO launch. Although this scenario may add a small amount of risk assembling transfer vehicles in Earth orbit, it should add no additional risk to the crew.

  8. VLBA "Movie" Gives Scientists New Insights On Workings of Mysterious Microquasars

    NASA Astrophysics Data System (ADS)

    2004-01-01

    Astronomers have made a 42-day movie showing unprecedented detail of the inner workings of a strange star system that has puzzled scientists for more than two decades. Their work is providing new insights that are changing scientists' understanding of the enigmatic stellar pairs known as microquasars. SS 433 Frame from SS 433 Movie: End to end is some 200 billion miles. CREDIT: Mioduszewski et al., NRAO/AUI/NSF Image Files Single Frame Overall Jet View (above image) VLBA Movie (animated gif, 2.3 MB) Animated graphic of SS 433 System (18MB) (Created using software by Robert Hynes, U.Texas) Annotated brightening graphic Unannotated brightening Frame 1 Unannotated brightening Frame 2 "This once-a-day series of exquisitely-detailed images is the best look anyone has ever had at a microquasar, and already has made us change our thinking about how these things work," said Amy Mioduszewski, of the National Radio Astronomy Observatory (NRAO), in Socorro, New Mexico. The astronomers used the National Science Foundation's Very Long Baseline Array (VLBA), a system of radio telescopes stretching from Hawaii to the Caribbean, to follow daily changes in a binary-star system called SS 433, some 15,000 light-years from Earth in the constellation Aquila. Mioduszewski worked with Michael Rupen, Greg Taylor and Craig Walker, all of NRAO. They reported their findings to the American Astronomical Society's meeting in Atlanta, Georgia. SS 433 consists of a neutron star or black hole orbited by a "normal" companion star. The powerful gravity of the neutron star or black hole is drawing material from the stellar wind of its companion into an accretion disk of material tightly circling the dense, central object prior to being pulled onto that object. This disk propels jets of subatomic particles outward from its poles. In SS 433, the particles in the jets move at 26 percent of the speed of light; in other microquasars, the jet material moves at 90-95 percent of light speed. The disk in SS

  9. Jet Fuel, Noise, and the Central Auditory Nervous System: A Literature Review.

    PubMed

    Warner, Rachelle; Fuente, Adrian; Hickson, Louise

    2015-09-01

    Prompted by the continued prevalence of hearing related disabilities accepted as eligible for compensation and treatment under Australian Department of Veterans' Affairs legislation, a review of recent literature regarding possible causation mechanisms and thus, possible prevention strategies, is timely. The emerging thoughts on the effects of a combination of jet fuel and noise exposure on the central auditory nervous system (CANS) have relevance in the military aviation context because of the high exposures to solvents (including fuels) and unique noise hazards related to weapons systems and military aircraft. This literature review aimed to identify and analyze the current knowledge base of the effects of combined exposure to JP-8 jet fuel (or its aromatic solvent components) and noise on the CANS in human populations. We reviewed articles examining electrophysiological and behavioral measurement of the CANS following combined exposures to jet fuel (or its aromatic constituents) and noise. A total of 6 articles met the inclusion criteria for the review and their results are summarized. The articles considered in this review indicate that assessment of the CANS should be undertaken as part of a comprehensive test battery for military members exposed to both noise and solvents in the workplace. Reprint & Copyright © 2015 Association of Military Surgeons of the U.S.

  10. Space Segment (SS) and the Navigation User Segment (US) Interface Control Document (ICD)

    DOT National Transportation Integrated Search

    1993-10-10

    This Interface Control Document (ICD) defines the requirements related to the interface between the Space Segment (SS) of the Global Positioning System (GPS) and the Navigation Users Segment of the GPS. 2880k, 154p.

  11. French validation of the Maslach Burnout Inventory-Student Survey (MBI-SS).

    PubMed

    Faye-Dumanget, Christine; Carré, Julie; Le Borgne, Margaux; Boudoukha, Pr Abdel Halim

    2017-12-01

    Several international studies have been conducted on student burnout. To contribute to the clinical examination as well as research on the mental health of students, the MBI-SS (Maslach Burnout Inventory-Student Survey) has been validated and used in different countries but not in French. The aim of this study is to examine the validity of the 3-dimensional model of the French version of the MBI-SS, which is characterized by emotional "Emotional Exhaustion" (EE); "Cynicism" (CY); and low scores in "Academic Efficacy" (AE). A total of 667 university students were questioned to study the 3-dimensional structure of the French translation of the MBI-SS. The results validate the 3-dimensional structure of the MBI-SS and indicate satisfactory psychometric values. It is concluded that the MBI-SS can be used to assess burnout in French students. © 2017 John Wiley & Sons, Ltd.

  12. The KIzSS network, a sentinel surveillance system for infectious diseases in day care centers: study protocol

    PubMed Central

    2012-01-01

    Background Day care-associated infectious diseases are widely recognized as a public health problem but rarely studied. Insights into their dynamics and their association with the day care setting are important for effective decision making in management of infectious disease control. This paper describes the purpose, design and potential of our national multi-center, day care-based sentinel surveillance network for infectious diseases (the KIzSS network). The aim of the KIzSS network is to acquire a long-term insight into the syndromic and microbiological aspects of day care-related infectious diseases and associated disease burden and to model these aspects with day care setting characteristics. Methods/design The KIzSS network applies a prospective cohort design, following day care centers rather than individual children or staff members over time. Data on infectious disease symptoms and related morbidity (children and staff), medical consumption, absenteeism and circulating enteric pathogens (children) are collected on a daily, weekly or monthly basis. Every two years, a survey is performed to assess the characteristics of participating day care centers. Discussion The KIzSS network offers a unique potential to study infectious disease dynamics in the day care setting over a sustained period of time. The created (bio)databases will help us to assess day care-related disease burden of infectious diseases among attending children and staff and their relation with the day care setting. This will support the much needed development of evidence-based and pragmatic guidelines for infectious disease control in day care centers. PMID:23066727

  13. MODELING SUPERSONIC-JET DEFLECTION IN THE HERBIG–HARO 110-270 SYSTEM WITH HIGH-POWER LASERS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yuan, Dawei; Li, Yutong; Lu, Xin

    Herbig–Haro (HH) objects associated with newly born stars are typically characterized by two high Mach number jets ejected in opposite directions. However, HH 110 appears to only have a single jet instead of two. Recently, Kajdi et al. measured the proper motions of knots in the whole system and noted that HH 110 is a continuation of the nearby HH 270. It has been proved that the HH 270 collides with the surrounding mediums and is deflected by 58°, reshaping itself as HH 110. Although the scales of the astrophysical objects are very different from the plasmas created in themore » laboratory, similarity criteria of physical processes allow us to simulate the jet deflection in the HH 110/270 system in the laboratory with high power lasers. A controllable and repeatable laboratory experiment could give us insight into the deflection behavior. Here we show a well downscaled experiment in which a laser-produced supersonic-jet is deflected by 55° when colliding with a nearby orthogonal side-flow. We also present a two-dimensional hydrodynamic simulation with the Euler program, LARED-S, to reproduce the deflection. Both are in good agreement. Our results show that the large deflection angle formed in the HH 110/270 system is probably due to the ram pressure from a flow–flow collision model.« less

  14. Inhalation of Hydrocarbon Jet Fuel Suppress Central Auditory Nervous System Function.

    PubMed

    Guthrie, O'neil W; Wong, Brian A; McInturf, Shawn M; Reboulet, James E; Ortiz, Pedro A; Mattie, David R

    2015-01-01

    More than 800 million L/d of hydrocarbon fuels is used to power cars, boats, and jet airplanes. The weekly consumption of these fuels necessarily puts the public at risk for repeated inhalation exposure. Recent studies showed that exposure to hydrocarbon jet fuel produces lethality in presynaptic sensory cells, leading to hearing loss, especially in the presence of noise. However, the effects of hydrocarbon jet fuel on the central auditory nervous system (CANS) have not received much attention. It is important to investigate the effects of hydrocarbons on the CANS in order to complete current knowledge regarding the ototoxic profile of such exposures. The objective of the current study was to determine whether inhalation exposure to hydrocarbon jet fuel might affect the functions of the CANS. Male Fischer 344 rats were randomly divided into four groups (control, noise, fuel, and fuel + noise). The structural and functional integrity of presynaptic sensory cells was determined in each group. Neurotransmission in both peripheral and central auditory pathways was simultaneously evaluated in order to identify and differentiate between peripheral and central dysfunctions. There were no detectable effects on pre- and postsynaptic peripheral functions. However, the responsiveness of the brain was significantly depressed and neural transmission time was markedly delayed. The development of CANS dysfunctions in the general public and the military due to cumulative exposure to hydrocarbon fuels may represent a significant but currently unrecognized public health issue.

  15. Jet angularity measurements for single inclusive jet production

    NASA Astrophysics Data System (ADS)

    Kang, Zhong-Bo; Lee, Kyle; Ringer, Felix

    2018-04-01

    We study jet angularity measurements for single-inclusive jet production at the LHC. Jet angularities depend on a continuous parameter a allowing for a smooth interpolation between different traditional jet shape observables. We establish a factorization theorem within Soft Collinear Effective Theory (SCET) where we consistently take into account in- and out-of-jet radiation by making use of semi-inclusive jet functions. For comparison, we elaborate on the differences to jet angularities measured on an exclusive jet sample. All the necessary ingredients for the resummation at next-to-leading logarithmic (NLL) accuracy are presented within the effective field theory framework. We expect semiinclusive jet angularity measurements to be feasible at the LHC and we present theoretical predictions for the relevant kinematic range. In addition, we investigate the potential impact of jet angularities for quark-gluon discrimination.

  16. CPV cells cooling system based on submerged jet impingement: CFD modeling and experimental validation

    NASA Astrophysics Data System (ADS)

    Montorfano, Davide; Gaetano, Antonio; Barbato, Maurizio C.; Ambrosetti, Gianluca; Pedretti, Andrea

    2014-09-01

    Concentrating photovoltaic (CPV) cells offer higher efficiencies with regard to the PV ones and allow to strongly reduce the overall solar cell area. However, to operate correctly and exploit their advantages, their temperature has to be kept low and as uniform as possible and the cooling circuit pressure drops need to be limited. In this work an impingement water jet cooling system specifically designed for an industrial HCPV receiver is studied. Through the literature and by means of accurate computational fluid dynamics (CFD) simulations, the nozzle to plate distance, the number of jets and the nozzle pitch, i.e. the distance between adjacent jets, were optimized. Afterwards, extensive experimental tests were performed to validate pressure drops and cooling power simulation results.

  17. An elevation of 0.1 light-seconds for the optical jet base in an accreting Galactic black hole system

    NASA Astrophysics Data System (ADS)

    Gandhi, P.; Bachetti, M.; Dhillon, V. S.; Fender, R. P.; Hardy, L. K.; Harrison, F. A.; Littlefair, S. P.; Malzac, J.; Markoff, S.; Marsh, T. R.; Mooley, K.; Stern, D.; Tomsick, J. A.; Walton, D. J.; Casella, P.; Vincentelli, F.; Altamirano, D.; Casares, J.; Ceccobello, C.; Charles, P. A.; Ferrigno, C.; Hynes, R. I.; Knigge, C.; Kuulkers, E.; Pahari, M.; Rahoui, F.; Russell, D. M.; Shaw, A. W.

    2017-12-01

    Relativistic plasma jets are observed in many systems that host accreting black holes. According to theory, coiled magnetic fields close to the black hole accelerate and collimate the plasma, leading to a jet being launched1-3. Isolating emission from this acceleration and collimation zone is key to measuring its size and understanding jet formation physics. But this is challenging because emission from the jet base cannot easily be disentangled from other accreting components. Here, we show that rapid optical flux variations from an accreting Galactic black-hole binary are delayed with respect to X-rays radiated from close to the black hole by about 0.1 seconds, and that this delayed signal appears together with a brightening radio jet. The origin of these subsecond optical variations has hitherto been controversial4-8. Not only does our work strongly support a jet origin for the optical variations but it also sets a characteristic elevation of ≲103 Schwarzschild radii for the main inner optical emission zone above the black hole9, constraining both internal shock10 and magnetohydrodynamic11 models. Similarities with blazars12,13 suggest that jet structure and launching physics could potentially be unified under mass-invariant models. Two of the best-studied jetted black-hole binaries show very similar optical lags8,14,15, so this size scale may be a defining feature of such systems.

  18. Microscopic Processes in Relativistic Jets

    NASA Technical Reports Server (NTRS)

    Nishikawa, K.-I.; Hardee, P.; Mizuno, Y.; Medvedev, M.; Zhang, B.; Nordlund, A.; Fredricksen, J.; Sol, H.; Niemiec, J.; Lyubarsky, Y.; hide

    2008-01-01

    Nonthermal radiation observed from astrophysical systems containing relativistic jets and shocks, e.g., gamma-ray bursts (GRBs), active galactic nuclei (AGNs), and Galactic microquasar systems usually have power-law emission spectra. Recent PIC simulations of relativistic electron-ion (electro-positron) jets injected into a stationary medium show that particle acceleration occurs within the downstream jet. In the collisionless relativistic shock particle acceleration is due to plasma waves and their associated instabilities (e.g., the Buneman instability, other two-streaming instability, and the Weibel (filamentation) instability) created in the shocks are responsible for particle (electron, positron, and ion) acceleration. The simulation results show that the Weibel instability is responsible for generating and amplifying highly nonuniform, small-scale magnetic fields. These magnetic fields contribute to the electron's transverse deflection behind the jet head. The 'jitter' radiation from deflected electrons has different properties than synchrotron radiation which is calculated in a uniform magnetic field. This jitter radiation may be important to understanding the complex time evolution and/or spectral structure in gamma-ray bursts, relativistic jets, and supernova remnants.

  19. Protostellar Jets: The Revolution with ALMA

    NASA Astrophysics Data System (ADS)

    Podio, Linda

    2017-11-01

    Fast and collimated molecular jets as well as slower wide-angle outflows are observed since the earliest stages of the formation of a new star, when the protostellar embryo accretes most of its final mass from the dense parental envelope. Early theoretical studies suggested that jets have a key role in this process as they can transport away angular momentum thus allowing the star to form without reaching its break-up speed. However, an observational validation of these theories is still challenging as it requires to investigate the interface between jets and disks on scales of fractions to tens of AUs. For this reason, many questions about the origin and feedback of protostellar jets remain unanswered, e.g. are jets ubiquitous at the earliest stages of star formation? Are they launched by a magneto-centrifugal mechanism as suggested by theoretical models? Are they able to remove (enough) angular momentum? What is the jet/outflow feedback on the forming star-disk system in terms of transported mass/momentum and shock-induced chemical alterations? The advent of millimetre interferometers such as NOEMA and ALMA with their unprecedented combination of angular resolution and sensitivity are now unraveling the core of pristine jet-disk systems. While NOEMA allows to obtain the first statistically relevant surveys of protostellar jet properties and ubiquity, recent ALMA observations provide the first solid signatures of jet rotation and new insight on the chemistry of the protostellar region. I will review the most recent and exciting results obtained in the field and show how millimetre interferometry is revolutionising our comprehension of protostellar jets.

  20. EuroPhenome and EMPReSS: online mouse phenotyping resource

    PubMed Central

    Mallon, Ann-Marie; Hancock, John M.

    2008-01-01

    EuroPhenome (http://www.europhenome.org) and EMPReSS (http://empress.har.mrc.ac.uk/) form an integrated resource to provide access to data and procedures for mouse phenotyping. EMPReSS describes 96 Standard Operating Procedures for mouse phenotyping. EuroPhenome contains data resulting from carrying out EMPReSS protocols on four inbred laboratory mouse strains. As well as web interfaces, both resources support web services to enable integration with other mouse phenotyping and functional genetics resources, and are committed to initiatives to improve integration of mouse phenotype databases. EuroPhenome will be the repository for a recently initiated effort to carry out large-scale phenotyping on a large number of knockout mouse lines (EUMODIC). PMID:17905814

  1. EuroPhenome and EMPReSS: online mouse phenotyping resource.

    PubMed

    Mallon, Ann-Marie; Blake, Andrew; Hancock, John M

    2008-01-01

    EuroPhenome (http://www.europhenome.org) and EMPReSS (http://empress.har.mrc.ac.uk/) form an integrated resource to provide access to data and procedures for mouse phenotyping. EMPReSS describes 96 Standard Operating Procedures for mouse phenotyping. EuroPhenome contains data resulting from carrying out EMPReSS protocols on four inbred laboratory mouse strains. As well as web interfaces, both resources support web services to enable integration with other mouse phenotyping and functional genetics resources, and are committed to initiatives to improve integration of mouse phenotype databases. EuroPhenome will be the repository for a recently initiated effort to carry out large-scale phenotyping on a large number of knockout mouse lines (EUMODIC).

  2. Subsonic Round and Rectangular Twin Jet Flow Effects

    NASA Technical Reports Server (NTRS)

    Bozak, Rick; Wernet, Mark

    2014-01-01

    Subsonic and supersonic aircraft concepts proposed by NASAs Fundamental Aeronautics Program have integrated propulsion systems with asymmetric nozzles. The asymmetry in the exhaust of these propulsion systems creates asymmetric flow and acoustic fields. The flow asymmetries investigated in the current study are from two parallel round, 2:1, and 8:1 aspect ratio rectangular jets at the same nozzle conditions. The flow field was measured with streamwise and cross-stream particle image velocimetry (PIV). A large dataset of single and twin jet flow field measurements was acquired at subsonic jet conditions. The effects of twin jet spacing and forward flight were investigated. For round, 2:1, and 8:1 rectangular twin jets at their closest spacings, turbulence levels between the two jets decreased due to enhanced jet mixing at near static conditions. When the flight Mach number was increased to 0.25, the flow around the twin jet model created a velocity deficit between the two nozzles. This velocity deficit diminished the effect of forward flight causing an increase in turbulent kinetic energy relative to a single jet. Both of these twin jet flow field effects decreased with increasing twin jet spacing relative to a single jet. These variations in turbulent kinetic energy correlate with changes in far-field sound pressure level.

  3. Demonstration and Optimization of BNFL's Pulsed Jet Mixing and RFD Sampling Systems Using NCAW Simulant

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    JR Bontha; GR Golcar; N Hannigan

    2000-08-29

    The BNFL Inc. flowsheet for the pretreatment and vitrification of the Hanford High Level Tank waste includes the use of several hundred Reverse Flow Diverters (RFDs) for sampling and transferring the radioactive slurries and Pulsed Jet mixers to homogenize or suspend the tank contents. The Pulsed Jet mixing and the RFD sampling devices represent very simple and efficient methods to mix and sample slurries, respectively, using compressed air to achieve the desired operation. The equipment has no moving parts, which makes them very suitable for mixing and sampling highly radioactive wastes. However, the effectiveness of the mixing and sampling systemsmore » are yet to be demonstrated when dealing with Hanford slurries, which exhibit a wide range of physical and theological properties. This report describes the results of the testing of BNFL's Pulsed Jet mixing and RFD sampling systems in a 13-ft ID and 15-ft height dish-bottomed tank at Battelle's 336 building high-bay facility using AZ-101/102 simulants containing up to 36-wt% insoluble solids. The specific objectives of the work were to: Demonstrate the effectiveness of the Pulsed Jet mixing system to thoroughly homogenize Hanford-type slurries over a range of solids loading; Minimize/optimize air usage by changing sequencing of the Pulsed Jet mixers or by altering cycle times; and Demonstrate that the RFD sampler can obtain representative samples of the slurry up to the maximum RPP-WTP baseline concentration of 25-wt%.« less

  4. Downregulation of SS18-SSX1 expression in synovial sarcoma by small interfering RNA enhances the focal adhesion pathway and inhibits anchorage-independent growth in vitro and tumor growth in vivo.

    PubMed

    Takenaka, Satoshi; Naka, Norifumi; Araki, Nobuhito; Hashimoto, Nobuyuki; Ueda, Takafumi; Yoshioka, Kiyoko; Yoshikawa, Hideki; Itoh, Kazuyuki

    2010-04-01

    Synovial sarcoma (SS) is an aggressive soft-tissue malignancy characterized by a unique t(X;18) translocation resulting in expression of SS18-SSX fusion protein. In order to investigate the biological function of this fusion protein and to develop a novel therapeutic option, we examined downregulation of SS18-SSX1 expression by small interfering RNA targeting SS18-SSX1 in three human SS cell lines. Microarray analysis comparing SS18-SSX1-silenced cells with control cells in three SS cell lines showed that SS18-SSX1 mainly affected the focal adhesion pathway. In accord with the array data, silencing of SS18-SSX1 enhances adhesion to the extracellular matrix through the induction of expression of myosin light-chain kinase. Furthermore, the silencing of SS18-SSX1 inhibits anchorage-independent growth in vitro and systemic delivery of siRNA against SS18-SSX1 using a nanoparticle system inhibited tumor growth in a nude mouse xenograft model. Our results demonstrate that siRNA targeting of SS18-SSX1 has therapeutic potential for the treatment of SS.

  5. Studies of supersonic, radiative plasma jet interaction with gases at the Prague Asterix Laser System facility

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nicolaie, Ph.; Stenz, C.; Tikhonchuk, V.

    2008-08-15

    The interaction of laser driven jets with gas puffs at various pressures is investigated experimentally and is analyzed by means of numerical tools. In the experiment, a combination of two complementary diagnostics allowed to characterize the main structures in the interaction zone. By changing the gas composition and its density, the plasma cooling time can be controlled and one can pass from a quasiadiabatic outflow to a strongly radiation cooling jet. This tuning yields hydrodynamic structures very similar to those seen in astrophysical objects; the bow shock propagating through the gas, the shocked materials, the contact discontinuity, and the Machmore » disk. From a dimensional analysis, a scaling is made between both systems and shows the study relevance for the jet velocity, the Mach number, the jet-gas density ratio, and the dissipative processes. The use of a two-dimensional radiation hydrodynamic code, confirms the previous analysis and provides detailed structure of the interaction zone and energy repartition between jet and surrounding gases.« less

  6. Ink-jet printing of silver metallization for photovoltaics

    NASA Technical Reports Server (NTRS)

    Vest, R. W.

    1986-01-01

    The status of the ink-jet printing program at Purdue University is described. The drop-on-demand printing system was modified to use metallo-organic decomposition (MOD) inks. Also, an IBM AT computer was integrated into the ink-jet printer system to provide operational functions and contact pattern configuration. The integration of the ink-jet printing system, problems encountered, and solutions derived were described in detail. The status of ink-jet printing using a MOD ink was discussed. The ink contained silver neodecanate and bismuth 2-ethylhexanoate dissolved in toluene; the MOD ink decomposition products being 99 wt% AG, and 1 wt% Bi.

  7. Control of ROS and RNS productions in liquid in atmospheric pressure plasma-jet system

    NASA Astrophysics Data System (ADS)

    Uchida, Giichiro; Ito, Taiki; Takenaka, Kosuke; Ikeda, Junichiro; Setsuhara, Yuichi

    2016-09-01

    Non-thermal plasma jets are of current interest in biomedical applications such as wound disinfection and even treatment of cancer tumors. Beneficial therapeutic effects in medical applications are attributed to excited species of oxygen and nitrogen from air. However, to control the production of these species in the plasma jet is difficult because their production is strongly dependent on concentration of nitrogen and oxygen from ambient air into the plasma jet. In this study, we analyze the discharge characteristics and the ROS and RNS productions in liquid in low- and high-frequency plasma-jet systems. Our experiments demonstrated the marked effects of surrounding gas near the plasma jet on ROS and RNS productions in liquid. By controlling the surround gas, the O2 and N2 main plasma jets are selectively produced even in open air. We also show that the concentration ratio of NO2- to H2O2 in liquid is precisely tuned from 0 to 0.18 in deionized water by changing N2 gas ratio (N2 / (N2 +O2)) in the main discharge gas, where high NO2- ratio is obtained at N2 gas ratio at N2 / (N2 +O2) = 0 . 8 . The low-frequency plasma jet with controlled surrounding gas is an effective plasma source for ROS and RNS productions in liquid, and can be a useful tool for biomedical applications. This study was partly supported by a Grant-in-Aid for Scientific Research on Innovative Areas ``Plasma Medical Innovation'' (24108003) from the Ministry of Education, Culture, Sports, Science and Technology, Japan (MEXT).

  8. Measurement of diabetic wounds with optical coherence tomography-based air-jet indentation system and a material testing system.

    PubMed

    Choi, M-C; Cheung, K-K; Ng, G Y-F; Zheng, Y-P; Cheing, G L-Y

    2015-11-01

    Material testing system is a conventional but destructive method for measuring the biomechanical properties of wound tissues in basic research. The recently developed optical coherence tomography-based air-jet indentation system is a non-destructive method for measuring these properties of soft tissues in a non-contact manner. The aim of the study was to examine the correlation between the biomechanical properties of wound tissues measured by the two systems. Young male Sprague-Dawley rats with streptozotocin-induced diabetic were wounded by a 6 mm biopsy punch on their hind limbs. The biomechanical properties of wound tissues were assessed with the two systems on post-wounding days 3, 7, 10, 14, and 21. Wound sections were stained with picro-sirius red for analysis on the collagen fibres. Data obtained on the different days were charted to obtain the change in biomechanical properties across the time points, and then pooled to examine the correlation between measurements made by the two devices. Qualitative analysis to determine any correlation between indentation stiffness measured by the air-jet indentation system and the orientation of collagen fibres. The indentation stiffness is significantly negatively correlated to the maximum load, maximum tensile stress, and Young's modulus by the material testing system (all p<0.05). The orientation of collagen changes with the indentation stiffness over time. Our findings support the use of optical coherence tomography-based air-jet indentation system to evaluate the biomechanical properties of wounds in a non-contact manner. It is a potential clinical device to examine the biomechanical properties of chronic wounds in vivo in a repeatable manner.

  9. Jet engine nozzle exit configurations and associated systems and methods

    NASA Technical Reports Server (NTRS)

    Mengle, Vinod G. (Inventor)

    2011-01-01

    Nozzle exit configurations and associated systems and methods are disclosed. An aircraft system in accordance with one embodiment includes a jet engine exhaust nozzle having an internal flow surface and an exit aperture, with the exit aperture having a perimeter that includes multiple projections extending in an aft direction. Aft portions of individual neighboring projections are spaced apart from each other by a gap, and a geometric feature of the multiple can change in a monotonic manner along at least a portion of the perimeter.

  10. Jet Engine Nozzle Exit Configurations and Associated Systems and Methods

    NASA Technical Reports Server (NTRS)

    Mengle, Vinod G. (Inventor)

    2013-01-01

    Nozzle exit configurations and associated systems and methods are disclosed. An aircraft system in accordance with one embodiment includes a jet engine exhaust nozzle having an internal flow surface and an exit aperture, with the exit aperture having a perimeter that includes multiple projections extending in an aft direction. Aft portions of individual neighboring projections are spaced apart from each other by a gap, and a geometric feature of the multiple can change in a monotonic manner along at least a portion of the perimeter.

  11. An evaluation of the relative fire hazards of jet A and jet B for commercial flight

    NASA Technical Reports Server (NTRS)

    Hibbard, R. R.; Hacker, P. T.

    1973-01-01

    The relative fire hazards of Jet A and Jet B aircraft fuels are evaluated. The evaluation is based on a consideration of the presence of and/or the generation of flammable mixtures in fuel systems, the ignition characteristics, and the flame propagation rates for the two fuel types. Three distinct aircraft operating regimes where fuel type may be a factor in fire hazards are considered. These are: (1) ground handling and refueling, (2) flight, and (3) crash. The evaluation indicates that the overall fire hazards for Jet A are less than for Jet B fuel.

  12. Immunotoxicity evaluation of jet a jet fuel in female rats after 28-day dermal exposure.

    PubMed

    Mann, Cynthia M; Peachee, Vanessa L; Trimmer, Gary W; Lee, Ji-Eun; Twerdok, Lorraine E; White, Kimber L

    2008-01-01

    The potential for jet fuel to modulate immune functions has been reported in mice following dermal, inhalation, and oral routes of exposure; however, a functional evaluation of the immune system in rats following jet fuel exposure has not been conducted. In this study potential effects of commercial jet fuel (Jet A) on the rat immune system were assessed using a battery of functional assays developed to screen potential immunotoxic compounds. Jet A was applied to the unoccluded skin of 6- to 7-wk-old female Crl:CD (SD)IGS BR rats at doses of 165, 330, or 495 mg/kg/d for 28 d. Mineral oil was used as a vehicle to mitigate irritation resulting from repeated exposure to jet fuel. Cyclophosphamide and anti-asialo GM1 were used as positive controls for immunotoxic effects. In contrast to reported immunotoxic effects of jet fuel in mice, dermal exposure of rats to Jet A did not result in alterations in spleen or thymus weights, splenic lymphocyte subpopulations, immunoglobulin (Ig) M antibody-forming cell response to the T-dependent antigen, sheep red blood cells (sRBC), spleen cell proliferative response to anti-CD3 antibody, or natural killer (NK) cell activity. In each of the immunotoxicological assays conducted, the positive control produced the expected results, demonstrating the assay was capable of detecting an effect if one had occurred. Based on the immunological parameters evaluated under the experimental conditions of the study, Jet A did not adversely affect immune responses of female rats. It remains to be determined whether the observed difference between this study and some other studies reflects a difference in the immunological response of rats and mice or is the result of other factors.

  13. Deflection of jets induced by jet-cloud and jet-galaxy interactions

    NASA Astrophysics Data System (ADS)

    Mendoza, S.; Longair, M. S.

    2001-06-01

    The model first introduced by Raga & Cantó in which astrophysical jets are deflected on passing through an isothermal high-density region is generalized by taking into account gravitational effects on the motion of the jet as it crosses the high-density cloud. The problem is also generalized for relativistic jets in which gravitational effects induced by the cloud are neglected. Two further cases, classical and relativistic, are discussed for the cases in which the jet is deflected on passing through the interstellar gas of a galaxy in which a dark matter halo dominates the gravitational potential. The criteria for the stability of jets due to the formation of internal shocks are also discussed.

  14. Gigantic Cosmic Corkscrew Reveals New Details About Mysterious Microquasar

    NASA Astrophysics Data System (ADS)

    2004-10-01

    Image of SS 433: Red-and-Blue Line Shows Path of Constant-Speed Jets. Note Poor Match of Path to Image. CREDIT: Blundell & Bowler, NRAO/AUI/NSF SS 433 Same Image, With Colored Beads Representing Particle Ejections at Different Speeds. Particle Path Now Matches. CREDIT: Blundell & Bowler, NRAO/AUI/NSF Click Here for Page of Full-Sized Graphics The new VLA image shows two full turns of the jets' corkscrew on both sides of the core. Analyzing the image showed that if material came from the core at a constant speed, the jet paths would not accurately match the details of the image. "By simulating ejections at varying speeds, we were able to produce an exact match to the observed structure," Blundell explained. The scientists first did their match to one of the jets. "We then were stunned to see that the varying speeds that matched the structure of one jet also exactly reproduced the other jet's path," Blundell said. Matching the speeds in the two jets reproduced the observed structure even allowing for the fact that, because one jet is moving more nearly away from us than the other, it takes light longer to reach us from it, she added. The astrophysicists speculate that the changes in ejection speed may be caused by changes in the rate at which material is transferred from the companion star onto the accretion disk. The detailed new VLA image also allowed the astrophysicists to determine that SS 433 is nearly 18,000 light-years distant from Earth. Earlier estimates had the object, in the constellation Aquila, as near as 10,000 light-years. An accurate distance, the scientists said, now allows them to better determine the age of the shell of debris blown out by the supernova explosion that created the dense, compact object in the microquasar. Knowing the distance accurately also allows them to measure the actual brightness of the microquasar's components, and this, they said, improves their understanding of the physical processes at work in the system. The breakthrough image

  15. Vessel thermal map real-time system for the JET tokamak

    NASA Astrophysics Data System (ADS)

    Alves, D.; Felton, R.; Jachmich, S.; Lomas, P.; McCullen, P.; Neto, A.; Valcárcel, D. F.; Arnoux, G.; Card, P.; Devaux, S.; Goodyear, A.; Kinna, D.; Stephen, A.; Zastrow, K.-D.

    2012-05-01

    The installation of international thermonuclear experimental reactor-relevant materials for the plasma facing components (PFCs) in the Joint European Torus (JET) is expected to have a strong impact on the operation and protection of the experiment. In particular, the use of all-beryllium tiles, which deteriorate at a substantially lower temperature than the formerly installed carbon fiber composite tiles, imposes strict thermal restrictions on the PFCs during operation. Prompt and precise responses are therefore required whenever anomalous temperatures are detected. The new vessel thermal map real-time application collects the temperature measurements provided by dedicated pyrometers and infrared cameras, groups them according to spatial location and probable offending heat source, and raises alarms that will trigger appropriate protective responses. In the context of the JET global scheme for the protection of the new wall, the system is required to run on a 10 ms cycle communicating with other systems through the real-time data network. In order to meet these requirements a commercial off-the-shelf solution has been adopted based on standard x86 multicore technology. Linux and the multithreaded application real-time executor (MARTe) software framework were respectively the operating system of choice and the real-time framework used to build the application. This paper presents an overview of the system with particular technical focus on the configuration of its real-time capability and the benefits of the modular development approach and advanced tools provided by the MARTe framework.

  16. Is PiSS Alpha-1 Antitrypsin Deficiency Associated with Disease?

    PubMed

    McGee, Dawn; Schwarz, Laura; McClure, Rebecca; Peterka, Lauren; Rouhani, Farshid; Brantly, Mark; Strange, Charlie

    2010-01-01

    Background. Alpha-1 antitrypsin deficiency (AAT) is an inherited condition that predisposes to lung and/or liver disease. Objective. The current study examined the clinical features of the PiSS genotype. Methods. Nineteen study participants (PiSS) and 29 matched control participants (PiMM) were telephone interviewed using a standardized questionnaire. Demographic features, cigarette smoking, vocation, medication history, and clinical diagnoses were compared. Statistical analysis was performed. Finally, a comprehensive literature review was performed by two investigators. Results. 12/19 (63.2%) study participants reported the presence of lung and/or liver disease compared to 12/29 (41.4%) control participants. There trended toward having a higher frequency of medication allergies in the study population (42.11% versus 20.69%). Conclusions. The PiSS genotype was associated with a similar incidence of obstructive lung disease to controls. Selective bias intrinsic in testing for AAT deficiency and the rarity of the PiSS genotype will make future study of this association dependent on population-based tests.

  17. Is PiSS Alpha-1 Antitrypsin Deficiency Associated with Disease?

    PubMed Central

    McGee, Dawn; Schwarz, Laura; McClure, Rebecca; Peterka, Lauren; Rouhani, Farshid; Brantly, Mark; Strange, Charlie

    2010-01-01

    Background. Alpha-1 antitrypsin deficiency (AAT) is an inherited condition that predisposes to lung and/or liver disease. Objective. The current study examined the clinical features of the PiSS genotype. Methods. Nineteen study participants (PiSS) and 29 matched control participants (PiMM) were telephone interviewed using a standardized questionnaire. Demographic features, cigarette smoking, vocation, medication history, and clinical diagnoses were compared. Statistical analysis was performed. Finally, a comprehensive literature review was performed by two investigators. Results. 12/19 (63.2%) study participants reported the presence of lung and/or liver disease compared to 12/29 (41.4%) control participants. There trended toward having a higher frequency of medication allergies in the study population (42.11% versus 20.69%). Conclusions. The PiSS genotype was associated with a similar incidence of obstructive lung disease to controls. Selective bias intrinsic in testing for AAT deficiency and the rarity of the PiSS genotype will make future study of this association dependent on population-based tests. PMID:21687342

  18. Performance Analysis of HF Band FB-MC-SS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hussein Moradi; Stephen Andrew Laraway; Behrouz Farhang-Boroujeny

    Abstract—In a recent paper [1] the filter bank multicarrier spread spectrum (FB-MC-SS) waveform was proposed for wideband spread spectrum HF communications. A significant benefit of this waveform is robustness against narrow and partial band interference. Simulation results in [1] demonstrated good performance in a wideband HF channel over a wide range of conditions. In this paper we present a theoretical analysis of the bit error probably for this system. Our analysis tailors the results from [2] where BER performance was analyzed for maximum ration combining systems that accounted for correlation between subcarriers and channel estimation error. Equations are give formore » BER that closely match the simulated performance in most situations.« less

  19. ssDNA damage dependence from singlet oxygen concentration at photodynamic interaction

    NASA Astrophysics Data System (ADS)

    Klimenko, V. V.; Kaydanov, N. E.; Emelyanov, A. K.; Bogdanov, A. A.

    2017-11-01

    Single stranded DNA damage at photodynamic treatment with Radachlorin photosensitizer was investigated. Chemical trap method was used to evaluate generation of singlet oxygen in water solution. Interaction of singlet oxygen with ssDNA resulted into decrease of the replication activity of ssDNA. DNA stopped replicating during PCR at irradiation doses greater than 15 J/cm2 and concentration of photosensitizer [PS] = 3.8 μM. The dependence of replication activity of ssDNA on generated singlet oxygen concentration was identified.

  20. Chandra enables study of x-ray jets

    PubMed Central

    Schwartz, Daniel

    2010-01-01

    The exquisite angular resolution of the Chandra x-ray telescope has enabled the detection and study of resolved x-ray jets in a wide variety of astronomical systems. Chandra has detected extended jets in our galaxy from protostars, symbiotic binaries, neutron star pulsars, black hole binaries, extragalactic jets in radio sources, and quasars. The x-ray data play an essential role in deducing the emission mechanism of the jets, in revealing the interaction of jets with the intergalactic or intracluster media, and in studying the energy generation budget of black holes. PMID:20378839

  1. Hypothalamic expression of KiSS-1 system and gonadotropin-releasing effects of kisspeptin in different reproductive states of the female Rat.

    PubMed

    Roa, J; Vigo, E; Castellano, J M; Navarro, V M; Fernández-Fernández, R; Casanueva, F F; Dieguez, C; Aguilar, E; Pinilla, L; Tena-Sempere, M

    2006-06-01

    Kisspeptins, products of the KiSS-1 gene with ability to bind G protein-coupled receptor 54 (GPR54), have been recently identified as major gatekeepers of reproductive function with ability to potently activate the GnRH/LH axis. Yet, despite the diversity of functional states of the female gonadotropic axis, pharmacological characterization of this effect has been mostly conducted in pubertal animals or adult male rodents, whereas similar studies have not been thoroughly conducted in the adult female. In this work, we evaluated maximal LH and FSH secretory responses to kisspeptin-10, as well as changes in sensitivity and hypothalamic expression of KiSS-1 and GPR54 genes, in different physiological and experimental models in the adult female rat. Kisspeptin-10 (1 nmol, intracerebroventricular) was able to elicit robust LH bursts at all phases of the estrous cycle, with maximal responses at estrus; yet, in diestrus LH, responses to kisspeptin were detected at doses as low as 0.1 pmol. In contrast, high doses of kisspeptin only stimulated FSH secretion at diestrus. Removal of ovarian sex steroids did not blunt the ability of kisspeptin to further elicit stimulated LH and FSH secretion, but restoration of maximal responses required replacement with estradiol and progesterone. Finally, despite suppressed basal levels, LH and FSH secretory responses to kisspeptin were preserved in pregnant and lactating females, although the magnitude of LH bursts and the sensitivity to kisspeptin were much higher in pregnant dams. Interestingly, hypothalamic KiSS-1 gene expression significantly increased during pregnancy, whereas GPR54 mRNA levels remained unaltered. In summary, our current data document for the first time the changes in hypothalamic expression of KiSS-1 system and the gonadotropic effects (maximal responses and sensitivity) of kisspeptin in different functional states of the female reproductive axis. The present data may pose interesting implications in light of the

  2. Benchmark studies of thermal jet mixing in SFRs using a two-jet model

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Omotowa, O. A.; Skifton, R.; Tokuhiro, A.

    To guide the modeling, simulations and design of Sodium Fast Reactors (SFRs), we explore and compare the predictive capabilities of two numerical solvers COMSOL and OpenFOAM in the thermal jet mixing of two buoyant jets typical of the outlet flow from a SFR tube bundle. This process will help optimize on-going experimental efforts at obtaining high resolution data for V and V of CFD codes as anticipated in next generation nuclear systems. Using the k-{epsilon} turbulence models of both codes as reference, their ability to simulate the turbulence behavior in similar environments was first validated for single jet experimental datamore » reported in literature. This study investigates the thermal mixing of two parallel jets having a temperature difference (hot-to-cold) {Delta}T{sub hc}= 5 deg. C, 10 deg. C and velocity ratios U{sub c}/U{sub h} = 0.5, 1. Results of the computed turbulent quantities due to convective mixing and the variations in flow field along the axial position are presented. In addition, this study also evaluates the effect of spacing ratio between jets in predicting the flow field and jet behavior in near and far fields. (authors)« less

  3. Ejector Noise Suppression with Auxiliary Jet Injection

    NASA Technical Reports Server (NTRS)

    Berman, Charles H.; Andersen, Otto P., Jr.

    1997-01-01

    An experimental program to reduce aircraft jet turbulence noise investigated the interaction of small auxiliary jets with a larger main jet. Significant reductions in the far field jet noise were obtained over a range of auxiliary jet pressures and flow rates when used in conjunction with an acoustically lined ejector. While the concept is similar to that of conventional ejector suppressors that use mechanical mixing devices, the present approach should improve thrust and lead to lower weight and less complex noise suppression systems since no hardware needs to be located in the main jet flow. A variety of auxiliary jet and ejector configurations and operating conditions were studied. The best conditions tested produced peak to peak noise reductions ranging from 11 to 16 dB, depending on measurement angle, for auxiliary jet mass flows that were 6.6% of the main jet flow with ejectors that were 8 times the main jet diameter in length. Much larger reductions in noise were found at the original peak frequencies of the unsuppressed jet over a range of far field measurement angles.

  4. ssDNA-dsRNAs are cleaved at the next to its chimera-junction point by an unknown RNase activity.

    PubMed

    Mochizuki, Shinichi; Higuchi, Sadaharu; Sakurai, Kazuo

    2012-11-30

    We found that there is an unknown aspect in serum RNases that cleaves ssDNA-dsRNA and ssRNA-dsRNA. In the first step, RNase cleaves the phosphodiester linkage between the first and second RNA, where the first one is connected to the single stranded RNA or DNA. In the second step, the ssRNA overhang attached siRNA is cleaved. When the 2' hydroxyl of the first RNA was replaced with methoxy, the cleavage did not occur. This RNase activity can be considered related to defense system against exogenous genetic materials. Copyright © 2012 Elsevier Inc. All rights reserved.

  5. Analysis of High Speed Jets Produced by a Servo Tube Driven Liquid Jet Injector

    NASA Astrophysics Data System (ADS)

    Portaro, Rocco; Ng, Hoi Dick

    2017-11-01

    In today's healthcare environment many types of medication must be administered through the use of hypodermic needles. Although this practice has been in use for many years, drawbacks such as accidental needle stick injuries, transmission of deadly viruses and bio-hazardous waste are still present. This study focuses on improving a needle free technology known as liquid jet injection, through the implementation of a linear servo tube actuator for the construction of a fully closed loop liquid jet injection system. This device has the ability to deliver both micro- and macro- molecules, high viscosity fluids whilst providing real time control of the jet pressure profile for accurate depth and dispersion control. The experiments are conducted using a prototype that consists of a 3 kW servo tube actuator, coupled to a specially designed injection head allowing nozzle size and injection volume to be varied. The device is controlled via a high speed servo amplifier and FPGA. The high speed jets emanating from the injector are assessed via high speed photography and through the use of a force transducer. Preliminary results indicate that the system allows for accurate shaping of the jet pressure profile, making it possible to target different tissue depths/types accurately.

  6. An atlas of H-alpha-emitting regions in M33: A systematic search for SS433 star candidates

    NASA Technical Reports Server (NTRS)

    Calzetti, Daniela; Kinney, Anne L.; Ford, Holland; Doggett, Jesse; Long, Knox S.

    1995-01-01

    We report finding charts and accurate positions for 432 compact H-alpha emitting regions in the Local Group galaxy M 33 (NGC 598), in an effort to isolate candidates for an SS433-like stellar system. The objects were extracted from narrow band images, centered in the rest-frame H-alpha (lambda 6563 A) and in the red continuum at 6100 A. The atlas is complete down to V approximately equal to 20 and includes 279 compact HII regions and 153 line emitting point-like sources. The point-like sources undoubtedly include a variety of objects: very small HII regions, early type stars with intense stellar winds, and Wolf-Rayet stars, but should also contain objects with the characteristics of SS433. This extensive survey of compact H-alpha regions in M 33 is a first step towards the identification of peculiar stellar systems like SS433 in external galaxies.

  7. Key steps in type III secretion system (T3SS) towards translocon assembly with potential sensor at plant plasma membrane.

    PubMed

    Ji, Hongtao; Dong, Hansong

    2015-09-01

    Many plant- and animal-pathogenic Gram-negative bacteria employ the type III secretion system (T3SS) to translocate effector proteins from bacterial cells into the cytosol of eukaryotic host cells. The effector translocation occurs through an integral component of T3SS, the channel-like translocon, assembled by hydrophilic and hydrophobic proteinaceous translocators in a two-step process. In the first, hydrophilic translocators localize to the tip of a proteinaceous needle in animal pathogens, or a proteinaceous pilus in plant pathogens, and associate with hydrophobic translocators, which insert into host plasma membranes in the second step. However, the pilus needs to penetrate plant cell walls in advance. All hydrophilic translocators so far identified in plant pathogens are characteristic of harpins: T3SS accessory proteins containing a unitary hydrophilic domain or an additional enzymatic domain. Two-domain harpins carrying a pectate lyase domain potentially target plant cell walls and facilitate the penetration of the pectin-rich middle lamella by the bacterial pilus. One-domain harpins target plant plasma membranes and may play a crucial role in translocon assembly, which may also involve contrapuntal associations of hydrophobic translocators. In all cases, sensory components in the target plasma membrane are indispensable for the membrane recognition of translocators and the functionality of the translocon. The conjectural sensors point to membrane lipids and proteins, and a phosphatidic acid and an aquaporin are able to interact with selected harpin-type translocators. Interactions between translocators and their sensors at the target plasma membrane are assumed to be critical for translocon assembly. © 2014 BSPP AND JOHN WILEY & SONS LTD.

  8. Pseudomonas aeruginosa uses T3SS to inhibit diabetic wound healing

    PubMed Central

    Goldufsky, Josef; Wood, Stephen J.; Jayaraman, Vijayakumar; Majdobeh, Omar; Chen, Lin; Qin, Shanshan; Zhang, Chunxiang; DiPietro, Luisa A.; Shafikhani, Sasha H.

    2015-01-01

    Diabetic foot ulcers are responsible for more hospitalizations than any other complication of diabetes. Bacterial infection is recognized as an important factor associated with impaired healing in diabetic ulcers. Pseudomonas aeruginosa is the most frequently detected Gram-negative pathogen in diabetic ulcers. P. aeruginosa infection has been shown to impair healing in diabetic wounds in a manner that correlates with its ability to form biofilm. While the majority of infections in diabetic ulcers are biofilm associated, 33% of infections are nonbiofilm in nature. P. aeruginosa is the most prevalent Gram-negative pathogen in all diabetic wound types, which suggests that the deleterious impact of P. aeruginosa on healing in diabetic wounds goes beyond its ability to form biofilm and likely involves other factors. The Type III Secretion System (T3SS) virulence structure is required for the pathogenesis of all P. aeruginosa clinical isolates, suggesting that it may also play a role in the inhibition of wound repair in diabetic skin ulcers. We evaluated the role of T3SS in mediating P. aeruginosa–induced tissue damage in the wounds of diabetic mice. Our data demonstrate that P. aeruginosa establishes a robust and persistent infection in diabetic wounds independent of its ability to form biofilm and causes severe wound damage in a manner that primarily depends on its T3SS. PMID:25912785

  9. Pseudomonas aeruginosa uses T3SS to inhibit diabetic wound healing.

    PubMed

    Goldufsky, Josef; Wood, Stephen J; Jayaraman, Vijayakumar; Majdobeh, Omar; Chen, Lin; Qin, Shanshan; Zhang, Chunxiang; DiPietro, Luisa A; Shafikhani, Sasha H

    2015-01-01

    Diabetic foot ulcers are responsible for more hospitalizations than any other complication of diabetes. Bacterial infection is recognized as an important factor associated with impaired healing in diabetic ulcers. Pseudomonas aeruginosa is the most frequently detected Gram-negative pathogen in diabetic ulcers. P. aeruginosa infection has been shown to impair healing in diabetic wounds in a manner that correlates with its ability to form biofilm. While the majority of infections in diabetic ulcers are biofilm associated, 33% of infections are nonbiofilm in nature. P. aeruginosa is the most prevalent Gram-negative pathogen in all diabetic wound types, which suggests that the deleterious impact of P. aeruginosa on healing in diabetic wounds goes beyond its ability to form biofilm and likely involves other factors. The Type III Secretion System (T3SS) virulence structure is required for the pathogenesis of all P. aeruginosa clinical isolates, suggesting that it may also play a role in the inhibition of wound repair in diabetic skin ulcers. We evaluated the role of T3SS in mediating P. aeruginosa-induced tissue damage in the wounds of diabetic mice. Our data demonstrate that P. aeruginosa establishes a robust and persistent infection in diabetic wounds independent of its ability to form biofilm and causes severe wound damage in a manner that primarily depends on its T3SS. © 2015 by the Wound Healing Society.

  10. TIMES-SS--recent refinements resulting from an industrial skin sensitisation consortium.

    PubMed

    Patlewicz, G; Kuseva, C; Mehmed, A; Popova, Y; Dimitrova, G; Ellis, G; Hunziker, R; Kern, P; Low, L; Ringeissen, S; Roberts, D W; Mekenyan, O

    2014-01-01

    The TImes MEtabolism Simulator platform for predicting Skin Sensitisation (TIMES-SS) is a hybrid expert system, first developed at Bourgas University using funding and data from a consortium of industry and regulators. TIMES-SS encodes structure-toxicity and structure-skin metabolism relationships through a number of transformations, some of which are underpinned by mechanistic 3D QSARs. The model estimates semi-quantitative skin sensitisation potency classes and has been developed with the aim of minimising animal testing, and also to be scientifically valid in accordance with the OECD principles for (Q)SAR validation. In 2007 an external validation exercise was undertaken to fully address these principles. In 2010, a new industry consortium was established to coordinate research efforts in three specific areas: refinement of abiotic reactions in the skin (namely autoxidation) in the skin, refinement of the manner in which chemical reactivity was captured in terms of structure-toxicity rules (inclusion of alert reliability parameters) and defining the domain based on the underlying experimental data (study of discrepancies between local lymph node assay Local Lymph Node Assay (LLNA) and Guinea Pig Maximisation Test (GPMT)). The present paper summarises the progress of these activities and explains how the insights derived have been translated into refinements, resulting in increased confidence and transparency in the robustness of the TIMES-SS predictions.

  11. Architecture and ssDNA interaction of the Timeless-Tipin-RPA complex

    PubMed Central

    Witosch, Justine; Wolf, Eva; Mizuno, Naoko

    2014-01-01

    The Timeless-Tipin (Tim-Tipin) complex, also referred to as the fork protection complex, is involved in coordination of DNA replication. Tim-Tipin is suggested to be recruited to replication forks via Replication Protein A (RPA) but details of the interaction are unknown. Here, using cryo-EM and biochemical methods, we characterized complex formation of Tim-Tipin, RPA and single-stranded DNA (ssDNA). Tim-Tipin and RPA form a 258 kDa complex with a 1:1:1 stoichiometry. The cryo-EM 3D reconstruction revealed a globular architecture of the Tim-Tipin-RPA complex with a ring-like and a U-shaped domain covered by a RPA lid. Interestingly, RPA in the complex adopts a horse shoe-like shape resembling its conformation in the presence of long ssDNA (>30 nucleotides). Furthermore, the recruitment of the Tim-Tipin-RPA complex to ssDNA is modulated by the RPA conformation and requires RPA to be in the more compact 30 nt ssDNA binding mode. The dynamic formation and disruption of the Tim-Tipin-RPA-ssDNA complex implicates the RPA-based recruitment of Tim-Tipin to the replication fork. PMID:25348395

  12. Further Characterization of a Type III Secretion System (T3SS) and of a New Effector Protein from a Clinical Isolate of Aeromonas Hydrophila - Part I

    EPA Science Inventory

    A type III secretion system (T3SS)-associated cytotoxin, AexT, with ADP-ribosyltransferase activity and homology to Pseudomonas aeruginosa bifuncational toxins ExoT/S, was recently identified from a fish pathogen Aeromonas salmonicida. In this study, we reported the molecular cha...

  13. Fuzzy jets

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mackey, Lester; Nachman, Benjamin; Schwartzman, Ariel

    Collimated streams of particles produced in high energy physics experiments are organized using clustering algorithms to form jets . To construct jets, the experimental collaborations based at the Large Hadron Collider (LHC) primarily use agglomerative hierarchical clustering schemes known as sequential recombination. We propose a new class of algorithms for clustering jets that use infrared and collinear safe mixture models. These new algorithms, known as fuzzy jets , are clustered using maximum likelihood techniques and can dynamically determine various properties of jets like their size. We show that the fuzzy jet size adds additional information to conventional jet tagging variablesmore » in boosted topologies. Furthermore, we study the impact of pileup and show that with some slight modifications to the algorithm, fuzzy jets can be stable up to high pileup interaction multiplicities.« less

  14. Fuzzy jets

    DOE PAGES

    Mackey, Lester; Nachman, Benjamin; Schwartzman, Ariel; ...

    2016-06-01

    Collimated streams of particles produced in high energy physics experiments are organized using clustering algorithms to form jets . To construct jets, the experimental collaborations based at the Large Hadron Collider (LHC) primarily use agglomerative hierarchical clustering schemes known as sequential recombination. We propose a new class of algorithms for clustering jets that use infrared and collinear safe mixture models. These new algorithms, known as fuzzy jets , are clustered using maximum likelihood techniques and can dynamically determine various properties of jets like their size. We show that the fuzzy jet size adds additional information to conventional jet tagging variablesmore » in boosted topologies. Furthermore, we study the impact of pileup and show that with some slight modifications to the algorithm, fuzzy jets can be stable up to high pileup interaction multiplicities.« less

  15. MUFOLD-SS: New deep inception-inside-inception networks for protein secondary structure prediction.

    PubMed

    Fang, Chao; Shang, Yi; Xu, Dong

    2018-05-01

    Protein secondary structure prediction can provide important information for protein 3D structure prediction and protein functions. Deep learning offers a new opportunity to significantly improve prediction accuracy. In this article, a new deep neural network architecture, named the Deep inception-inside-inception (Deep3I) network, is proposed for protein secondary structure prediction and implemented as a software tool MUFOLD-SS. The input to MUFOLD-SS is a carefully designed feature matrix corresponding to the primary amino acid sequence of a protein, which consists of a rich set of information derived from individual amino acid, as well as the context of the protein sequence. Specifically, the feature matrix is a composition of physio-chemical properties of amino acids, PSI-BLAST profile, and HHBlits profile. MUFOLD-SS is composed of a sequence of nested inception modules and maps the input matrix to either eight states or three states of secondary structures. The architecture of MUFOLD-SS enables effective processing of local and global interactions between amino acids in making accurate prediction. In extensive experiments on multiple datasets, MUFOLD-SS outperformed the best existing methods and other deep neural networks significantly. MUFold-SS can be downloaded from http://dslsrv8.cs.missouri.edu/~cf797/MUFoldSS/download.html. © 2018 Wiley Periodicals, Inc.

  16. [Kelvin-Helmholtz instability in protostellar jets

    NASA Technical Reports Server (NTRS)

    Stone, James; Hardee, Philip

    1996-01-01

    NASA grant NAG 5 2866, funded by the Astrophysics Theory Program, enabled the study the Kelvin-Helmholtz instability in protostellar jets. In collaboration with co-investigator Philip Hardee, the PI derived the analytic dispersion relation for the instability in including a cooling term in the energy equation which was modeled as one of two different power laws. Numerical solutions to this dispersion relation over a wide range of perturbation frequencies, and for a variety of parameter values characterizing the jet (such as Mach number, and density ratio) were found It was found that the growth rates and wavelengths associated with unstable roots of the dispersion relation in cooling jets are significantly different than those associated with adiabatic jets, which have been studied previously. In collaboration with graduate student Jianjun Xu (funded as a research associate under this grant), hydrodynamical simulations were used to follow the growth of the instability into the nonlinear regime. It was found that asymmetric surface waves lead to large amplitude, sinusoidal distortions of the jet, and ultimately to disruption Asymmetric body waves, on the other hand, result in the formation of shocks in the jet beam in the nonlinear regime. In cooling jets, these shocks lead to the formation of dense knots and filaments of gas within the jet. For sufficiently high perturbation frequencies, however, the jet cannot respond and it remains symmetric. Applying these results to observed systems, such as the Herbig-Haro jets HH34, HH111 and HH47 which have been observed with the Hubble Space Telescope, we predicted that some of the asymmetric structures observed in these systems could be attributed to the K-H modes, but that perturbations on timescales associated with the inner disk (about 1 year) would be too rapid to cause disruption. Moreover, it was discovered that weak shock 'spurs' in the ambient gas produced by ripples in the jet surface due to nonlinear, modes of

  17. Numerical investigation on properties of attack angle for an opposing jet thermal protection system

    NASA Astrophysics Data System (ADS)

    Lu, Hai-Bo; Liu, Wei-Qiang

    2012-08-01

    The three-dimensional Navier—Stokes equation and the k-in viscous model are used to simulate the attack angle characteristics of a hemisphere nose-tip with an opposing jet thermal protection system in supersonic flow conditions. The numerical method is validated by the relevant experiment. The flow field parameters, aerodynamic forces, and surface heat flux distributions for attack angles of 0°, 2°, 5°, 7°, and 10° are obtained. The detailed numerical results show that the cruise attack angle has a great influence on the flow field parameters, aerodynamic force, and surface heat flux distribution of the supersonic vehicle nose-tip with an opposing jet thermal protection system. When the attack angle reaches 10°, the heat flux on the windward generatrix is close to the maximal heat flux on the wall surface of the nose-tip without thermal protection system, thus the thermal protection has failed.

  18. Damage Analysis of Tensile Deformation of Co-rolled SMATed 304SS

    NASA Astrophysics Data System (ADS)

    Guo, X.; Leung, A. Y. T.; Chen, A.; Ruan, H.; Lu, J.

    2010-05-01

    One of recent experimental progresses in strengthening and toughening metals simultaneously is to adopt techniques of surface mechanical attrition treatment (SMAT) and warm co-rolling to 304 stainless steel (SS). To capture deformation behavior and associated damage initiation/evolution process in the co-rolled SMATed 304SS, cohesive finite element method (CFEM) is employed in this paper and simulation results are in agreement with experimental results. Both strengthening effect due to high yield stress of the nanograin layer and toughening effect due to non-localized damage in the nanograin layer are captured. Effect of energy release rate of nanograin layer on failure strain of layered co-rolled SMATed 304SS is investigated. It is found that the more brittle the nanograin layer is, the more potential necking sites in the nanograin layer are, and the more ductile the layered co-rolled SMATed 304SS is.

  19. Heat convection in a micro impinging jet system

    NASA Astrophysics Data System (ADS)

    Mai, John Dzung Hoang

    2000-10-01

    This thesis covers the development of an efficient micro impinging jet heat exchanger, using MEMS technology, to provide localized cooling for present and next generation microelectronic computer chips. Before designing an efficient localized heat exchanger, it is necessary to investigate fluid dynamics and heat transfer in the micro scale. MEMS technology has been used in this project because it is the only tool currently available that can provide a large array of batch-fabricated, micro-scale nozzles for localized cooling. Our investigation of potential MEMS heat exchanger designs begins with experiments that measure the pressure drops and temperature changes in a micro scale tubing system that will be necessary to carry fluid to the impingement point. Our basic MEMS model is a freestanding micro channel with integrated temperature microsensors. The temperature distribution along the channel in a vacuum is measured. The measured flow rates are compared with an analytical model developed for capillary flow that accounts for 2-D, slip and compressibility effects. The work is focused on obtaining correlations in the form of the Nussult number, the Reynolds number and a H/d geometric factor. A set of single MEMS nozzles have been designed to test heat transfer effectiveness as a function of nozzle diameter, ranging from 1.0 mm to 250 um. In addition, nozzle and slot array MEMS devices have been fabricated. In order to obtain quantitative measurements from these micron scale devices, a series of target temperature sensor chips were custom made and characterized for these experiments. The heat transfer characteristics of various MEMS nozzle configurations operating at various steady inlet pressures, at different heights above the heated substrate, have been characterized. These steady results showed that the average heat transfer coefficient, averaged over a 1 cm2 test area, was usually less than 0.035 W/cm 2K for any situation. However, the local heat transfer

  20. Architecture and ssDNA interaction of the Timeless-Tipin-RPA complex.

    PubMed

    Witosch, Justine; Wolf, Eva; Mizuno, Naoko

    2014-11-10

    The Timeless-Tipin (Tim-Tipin) complex, also referred to as the fork protection complex, is involved in coordination of DNA replication. Tim-Tipin is suggested to be recruited to replication forks via Replication Protein A (RPA) but details of the interaction are unknown. Here, using cryo-EM and biochemical methods, we characterized complex formation of Tim-Tipin, RPA and single-stranded DNA (ssDNA). Tim-Tipin and RPA form a 258 kDa complex with a 1:1:1 stoichiometry. The cryo-EM 3D reconstruction revealed a globular architecture of the Tim-Tipin-RPA complex with a ring-like and a U-shaped domain covered by a RPA lid. Interestingly, RPA in the complex adopts a horse shoe-like shape resembling its conformation in the presence of long ssDNA (>30 nucleotides). Furthermore, the recruitment of the Tim-Tipin-RPA complex to ssDNA is modulated by the RPA conformation and requires RPA to be in the more compact 30 nt ssDNA binding mode. The dynamic formation and disruption of the Tim-Tipin-RPA-ssDNA complex implicates the RPA-based recruitment of Tim-Tipin to the replication fork. © The Author(s) 2014. Published by Oxford University Press on behalf of Nucleic Acids Research.

  1. Identification of microorganisms isolated from jet fuel systems.

    PubMed

    Edmonds, P; Cooney, J J

    1967-03-01

    Seventy-two samples from jet aircraft fuel systems were examined for microbial contamination. Ten contaminated samples yielded 43 microorganisms which were classified into nine genera of bacteria and three genera of fungi. The predominant types, comprising about 37% of the isolated cultures, were identified as Bacillus spp. The remaining cultures were distributed among 11 genera, each of which represented 2 to 9% of the total isolates. Four cultures could not be assigned to a genus on the basis of the diagnostic criteria used. Only five isolates, in the genera Pseudomonas and Hormodendrum (Cladosporium), grew abundantly in a mineral salts solution with JP-4 fuel as the sole source of carbon. The presence of fuel utilizers in a fuel system may be a better index to potential problems that have been correlated with microbial contamination than the presence of aerobic sporeforming bacilli.

  2. Magnetically driven jets and winds

    NASA Technical Reports Server (NTRS)

    Lovelace, R. V. E.; Berk, H. L.; Contopoulos, J.

    1991-01-01

    Four equations for the origin and propagation of nonrelativistic jets and winds are derived from the basic conservation laws of ideal MHD. The axial current density is negative in the vicinity of the axis and positive at larger radii; there is no net current because this is energetically favored. The magnetic field is essential for the jet solutions in that the zz-component of the magnetic stress acts, in opposition to gravity, to drive matter through the slow magnetosonic critical point. For a representative self-consistent disk/jet solution relevant to a protostellar system, the reaction of the accreted mass expelled in the jets is 0.1, the ratio of the power carried by the jets to the disk luminosity is 0.66, and the ratio of the boundary layer to disk luminosities is less than about 0.13. The star's rotation rate decreases with time even for rotation rates much less than the breakup rate.

  3. Influence of membrane fouling reducers (MFRs) on filterability of disperse mixed liquor of jet loop bioreactors.

    PubMed

    Koseoglu-Imer, Derya Yuksel; Dizge, Nadir; Karagunduz, Ahmet; Keskinler, Bulent

    2011-07-01

    The effects of membrane fouling reducers (MFRs) (the cationic polyelectrolyte (CPE) and FeCI(3)) on membrane fouling were studied in a lab-scale jet loop submerged membrane bioreactor (JL-SMBR) system. The optimum dosages of MFRs (CPE dosage=20 mg g(-1)MLSS, FeCI(3) dosage=14 mg g(-1)MLSS) were continuously fed to JL-SMBR system. The soluble and bound EPS concentrations as well as MLSS concentration in the mixed liquor of JL-SMBR were not changed substantially by the addition of MFRs. However, significant differences were observed in particle size and relative hydrophobicity. Filtration tests were performed by using different membrane types (polycarbonate (PC) and nitrocellulose mixed ester (ME)) and various pore sizes (0.45-0.22-0.1 μm). The steady state fluxes (J(ss)) of membranes increased at all membranes after MFRs addition to JL-SMBR. The filtration results showed that MFRs addition was an effective approach in terms of improvement in filtration performance for both membrane types. Copyright © 2011 Elsevier Ltd. All rights reserved.

  4. RPA homologs and ssDNA processing during meiotic recombination.

    PubMed

    Ribeiro, Jonathan; Abby, Emilie; Livera, Gabriel; Martini, Emmanuelle

    2016-06-01

    Meiotic homologous recombination is a specialized process that involves homologous chromosome pairing and strand exchange to guarantee proper chromosome segregation and genetic diversity. The formation and repair of DNA double-strand breaks (DSBs) during meiotic recombination differs from those during mitotic recombination in that the homologous chromosome rather than the sister chromatid is the preferred repair template. The processing of single-stranded DNA (ssDNA) formed on intermediate recombination structures is central to driving the specific outcomes of DSB repair during meiosis. Replication protein A (RPA) is the main ssDNA-binding protein complex involved in DNA metabolism. However, the existence of RPA orthologs in plants and the recent discovery of meiosis specific with OB domains (MEIOB), a widely conserved meiosis-specific RPA1 paralog, strongly suggest that multiple RPA complexes evolved and specialized to subdivide their roles during DNA metabolism. Here we review ssDNA formation and maturation during mitotic and meiotic recombination underlying the meiotic specific features. We describe and discuss the existence and properties of MEIOB and multiple RPA subunits in plants and highlight how they can provide meiosis-specific fates to ssDNA processing during homologous recombination. Understanding the functions of these RPA homologs and how they interact with the canonical RPA subunits is of major interest in the fields of meiosis and DNA repair.

  5. Effect of reaction control system jet-flow field interactions on a 0.015 scale model space shuttle orbiter aerodynamic characteristics

    NASA Technical Reports Server (NTRS)

    Monta, W. J.; Rausch, J. R.

    1973-01-01

    The effects of the reaction control system (RCS) jet-flow field interactions on the space shuttle orbiter system during entry are discussed. The primary objective of the test program was to obtain data for the shuttle orbiter configuration to determine control amplification factors resulting from jet interaction between the RCS plumes and the external flow over the vehicle. A secondary objective was to provide data for comparison and improvement of analytic jet interaction prediction techniques. The test program was divided into two phases; (1) force and moment measurements were made with and without RCS blowing, investigating environment parameters (R sub e, Alpha, Beta), RCS plume parameters (Jet pressure ratio, momentum ratio and thrust level), and geometry parameters (RCS pod locations) on the orbiter model, (2) oil flow visualization tests were conducted on a dummy balance at the end of the test.

  6. Very high resolution observations of SS433 at 10.65 GHz

    NASA Technical Reports Server (NTRS)

    Geldzahler, B. J.; Downes, A. J. B.; Shaffer, D. B.

    1981-01-01

    Observations of SS433 made on June 12, 1979, from West Germany, Massachusetts, and West Virginia are discussed. It is noted that SS433 did not show fringes on any baseline although all the calibration sources were seen at their expected strengths. The measured total flux density of SS433 was found to be approximately 0.5 Jy, consistent with previous observations. The source was observed by on-offs at each telescope, which indicates that they were all pointed properly during the observations. The absence of fringes is not attributed to poor observing conditions or instrumental difficulties. It is concluded that if all the 10.65 GHz radiation emanates from a single component, then that component is at least 0.005 arcsec (approximately 10 to the 14th cm) in size. The measurements made on more sensitive intercontinental baselines indicate that there is no component of SS433 smaller than 0.001 arcsec emitting 10.65 GHz radiation above a level of 50 mJy.

  7. Nuclear Thermal Rocket - Arc Jet Integrated System Model

    NASA Technical Reports Server (NTRS)

    Taylor, Brian D.; Emrich, William

    2016-01-01

    In the post-shuttle era, space exploration is moving into a new regime. Commercial space flight is in development and is planned to take on much of the low earth orbit space flight missions. With the development of a heavy lift launch vehicle, the Space Launch, System, NASA has become focused on deep space exploration. Exploration into deep space has traditionally been done with robotic probes. More ambitious missions such as manned missions to asteroids and Mars will require significant technology development. Propulsion system performance is tied to the achievability of these missions and the requirements of other developing technologies that will be required. Nuclear thermal propulsion offers a significant improvement over chemical propulsion while still achieving high levels of thrust. Opportunities exist; however, to build upon what would be considered a standard nuclear thermal engine to attain improved performance, thus further enabling deep space missions. This paper discuss the modeling of a nuclear thermal system integrated with an arc jet to further augment performance. The performance predictions and systems impacts are discussed.

  8. An improved DNA force field for ssDNA interactions with gold nanoparticles

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jiang, Xiankai; Huai, Ping; Fan, Chunhai

    The widespread applications of single-stranded DNA (ssDNA) conjugated gold nanoparticles (AuNPs) have spurred an increasing interest in the interactions between ssDNA and AuNPs. Despite extensive studies using the most sophisticated experimental techniques, the detailed molecular mechanisms still remain largely unknown. Large scale molecular dynamics (MD) simulations can thus be used to supplement experiments by providing complementary information about ssDNA-AuNP interactions. However, up to now, all modern force fields for DNA were developed based on the properties of double-stranded DNA (dsDNA) molecules, which have hydrophilic outer backbones “protecting” hydrophobic inner nucleobases from water. Without the double-helix structure of dsDNA and thusmore » the “protection” by the outer backbone, the nucleobases of ssDNA are directly exposed to solvent, and their behavior in water is very different from that of dsDNA, especially at the interface with nanoparticles. In this work, we have improved the force field of ssDNA for use with nanoparticles, such as AuNPs, based on recent experimental results and quantum mechanics calculations. With the new improved force field, we demonstrated that a poly(A) sequence adsorbed on a AuNP surface is much more stable than a poly(T) sequence, which is consistent with recent experimental observations. On the contrary, the current standard force fields, including AMBER03, CHARMM27, and OPLSAA, all gave erroneous results as compared to experiments. The current improved force field is expected to have wide applications in the study of ssDNA with nanomaterials including AuNPs, which might help promote the development of ssDNA-based biosensors and other bionano-devices.« less

  9. An improved DNA force field for ssDNA interactions with gold nanoparticles

    NASA Astrophysics Data System (ADS)

    Jiang, Xiankai; Gao, Jun; Huynh, Tien; Huai, Ping; Fan, Chunhai; Zhou, Ruhong; Song, Bo

    2014-06-01

    The widespread applications of single-stranded DNA (ssDNA) conjugated gold nanoparticles (AuNPs) have spurred an increasing interest in the interactions between ssDNA and AuNPs. Despite extensive studies using the most sophisticated experimental techniques, the detailed molecular mechanisms still remain largely unknown. Large scale molecular dynamics (MD) simulations can thus be used to supplement experiments by providing complementary information about ssDNA-AuNP interactions. However, up to now, all modern force fields for DNA were developed based on the properties of double-stranded DNA (dsDNA) molecules, which have hydrophilic outer backbones "protecting" hydrophobic inner nucleobases from water. Without the double-helix structure of dsDNA and thus the "protection" by the outer backbone, the nucleobases of ssDNA are directly exposed to solvent, and their behavior in water is very different from that of dsDNA, especially at the interface with nanoparticles. In this work, we have improved the force field of ssDNA for use with nanoparticles, such as AuNPs, based on recent experimental results and quantum mechanics calculations. With the new improved force field, we demonstrated that a poly(A) sequence adsorbed on a AuNP surface is much more stable than a poly(T) sequence, which is consistent with recent experimental observations. On the contrary, the current standard force fields, including AMBER03, CHARMM27, and OPLSAA, all gave erroneous results as compared to experiments. The current improved force field is expected to have wide applications in the study of ssDNA with nanomaterials including AuNPs, which might help promote the development of ssDNA-based biosensors and other bionano-devices.

  10. An improved DNA force field for ssDNA interactions with gold nanoparticles.

    PubMed

    Jiang, Xiankai; Gao, Jun; Huynh, Tien; Huai, Ping; Fan, Chunhai; Zhou, Ruhong; Song, Bo

    2014-06-21

    The widespread applications of single-stranded DNA (ssDNA) conjugated gold nanoparticles (AuNPs) have spurred an increasing interest in the interactions between ssDNA and AuNPs. Despite extensive studies using the most sophisticated experimental techniques, the detailed molecular mechanisms still remain largely unknown. Large scale molecular dynamics (MD) simulations can thus be used to supplement experiments by providing complementary information about ssDNA-AuNP interactions. However, up to now, all modern force fields for DNA were developed based on the properties of double-stranded DNA (dsDNA) molecules, which have hydrophilic outer backbones "protecting" hydrophobic inner nucleobases from water. Without the double-helix structure of dsDNA and thus the "protection" by the outer backbone, the nucleobases of ssDNA are directly exposed to solvent, and their behavior in water is very different from that of dsDNA, especially at the interface with nanoparticles. In this work, we have improved the force field of ssDNA for use with nanoparticles, such as AuNPs, based on recent experimental results and quantum mechanics calculations. With the new improved force field, we demonstrated that a poly(A) sequence adsorbed on a AuNP surface is much more stable than a poly(T) sequence, which is consistent with recent experimental observations. On the contrary, the current standard force fields, including AMBER03, CHARMM27, and OPLSAA, all gave erroneous results as compared to experiments. The current improved force field is expected to have wide applications in the study of ssDNA with nanomaterials including AuNPs, which might help promote the development of ssDNA-based biosensors and other bionano-devices.

  11. Discrimination against RNA Backbones by a ssDNA Binding Protein.

    PubMed

    Lloyd, Neil R; Wuttke, Deborah S

    2018-05-01

    Pot1 is the shelterin component responsible for the protection of the single-stranded DNA (ssDNA) overhang at telomeres in nearly all eukaryotic organisms. The C-terminal domain of the DNA-binding domain, Pot1pC, exhibits non-specific ssDNA recognition, achieved through thermodynamically equivalent alternative binding conformations. Given this flexibility, it is unclear how specificity for ssDNA over RNA, an activity required for biological function, is achieved. Examination of the ribose-position specificity of Pot1pC shows that ssDNA specificity is additive but not uniformly distributed across the ligand. High-resolution structures of several Pot1pC complexes with RNA-DNA chimeric ligands reveal Pot1pC discriminates against RNA by utilizing non-compensatory binding modes that feature significant rearrangement of the binding interface. These alternative conformations, accessed through both ligand and protein flexibility, recover much, but not all, of the binding energy, leading to the observed reduction in affinities. These findings suggest that intermolecular interfaces are remarkably sophisticated in their tuning of specificity toward flexible ligands. Copyright © 2018 Elsevier Ltd. All rights reserved.

  12. Karl Blumenreuter (1881-1969): Himmler's chief pharmacist and medical supply quartermaster of the SS.

    PubMed

    Schmidt, M; Gross, D; Westemeier, J

    2018-04-02

    The present article elucidates the role and function of SS Gruppenführer Karl Blumenreuter (1881-1969), the leading pharmacist of the SS. The aim is to clarify how he participated in the crimes of the Nazi Party and especially the SS during the "Third Reich" and the extent to which he was brought to justice after 1945. Central elements of the study are based on researched archival primary sources. The latter were compared with each other and supplemented with the currently available secondary literature on the subject. It can be established that Blumenreuter was a zealous National Socialist with marked career ambitions who advanced within the SS to the rank of SS Gruppenführer and Lieutenant General of the Waffen SS (Generalleutnant der Waffen SS). He supplied pre-measured phenol ampoules for the murder of prisoners in the concentration camps. Blumenreuter furthermore organised equipment and material supplies for various experiments on humans. After 1945 he succeeded in playing down his participation in the crimes in the time of National Socialism. Blumenreuter died in 1969 without having being brought to justice by the judiciary and without having reflected self-critically on his role in the "Third Reich".

  13. Characterization of Three-Stream Jet Flow Fields

    NASA Technical Reports Server (NTRS)

    Henderson, Brenda S.; Wernet, Mark P.

    2016-01-01

    Flow-field measurements were conducted on single-, dual- and three-stream jets using two-component and stereo Particle Image Velocimetry (PIV). The flow-field measurements complimented previous acoustic measurements. The exhaust system consisted of externally-plugged, externally-mixed, convergent nozzles. The study used bypass-to-core area ratios equal to 1.0 and 2.5 and tertiary-to-core area ratios equal to 0.6 and 1.0. Axisymmetric and offset tertiary nozzles were investigated for heated and unheated high-subsonic conditions. Centerline velocity decay rates for the single-, dual- and three-stream axisymmetric jets compared well when axial distance was normalized by an equivalent diameter based on the nozzle system total exit area. The tertiary stream had a greater impact on the mean axial velocity for the small bypass-to-core area ratio nozzles than for large bypass-to-core area ratio nozzles. Normalized turbulence intensities were similar for the single-, dual-, and three-stream unheated jets due to the small difference (10 percent) in the core and bypass velocities for the dual-stream jets and the low tertiary velocity (50 percent of the core stream) for the three-stream jets. For heated jet conditions where the bypass velocity was 65 percent of the core velocity, additional regions of high turbulence intensity occurred near the plug tip which were not present for the unheated jets. Offsetting the tertiary stream moved the peak turbulence intensity levels upstream relative to those for all axisymmetric jets investigated.

  14. Characterization of Three-Stream Jet Flow Fields

    NASA Technical Reports Server (NTRS)

    Henderson, Brenda S.; Wernet, Mark P.

    2016-01-01

    Flow-field measurements were conducted on single-, dual- and three-stream jets using two-component and stereo Particle Image Velocimetry (PIV). The flow-field measurements complimented previous acoustic measurements. The exhaust system consisted of externally-plugged, externally-mixed, convergent nozzles. The study used bypass-to-core area ratios equal to 1.0 and 2.5 and tertiary-to-core area ratios equal to 0.6 and 1.0. Axisymmetric and offset tertiary nozzles were investigated for heated and unheated high-subsonic conditions. Centerline velocity decay rates for the single-, dual- and three-stream axisymmetric jets compared well when axial distance was normalized by an equivalent diameter based on the nozzle system total exit area. The tertiary stream had a greater impact on the mean axial velocity for the small bypass-to-core area ratio nozzles than for large bypass-to-core area ratio nozzles. Normalized turbulence intensities were similar for the single-, dual-, and three-stream unheated jets due to the small difference (10%) in the core and bypass velocities for the dual-stream jets and the low tertiary velocity (50% of the core stream) for the three-stream jets. For heated jet conditions where the bypass velocity was 65% of the core velocity, additional regions of high turbulence intensity occurred near the plug tip which were not present for the unheated jets. Offsetting the tertiary stream moved the peak turbulence intensity levels upstream relative to those for all axisymmetric jets investigated.

  15. Assuring SS7 dependability: A robustness characterization of signaling network elements

    NASA Astrophysics Data System (ADS)

    Karmarkar, Vikram V.

    1994-04-01

    Current and evolving telecommunication services will rely on signaling network performance and reliability properties to build competitive call and connection control mechanisms under increasing demands on flexibility without compromising on quality. The dimensions of signaling dependability most often evaluated are the Rate of Call Loss and End-to-End Route Unavailability. A third dimension of dependability that captures the concern about large or catastrophic failures can be termed Network Robustness. This paper is concerned with the dependability aspects of the evolving Signaling System No. 7 (SS7) networks and attempts to strike a balance between the probabilistic and deterministic measures that must be evaluated to accomplish a risk-trend assessment to drive architecture decisions. Starting with high-level network dependability objectives and field experience with SS7 in the U.S., potential areas of growing stringency in network element (NE) dependability are identified to improve against current measures of SS7 network quality, as per-call signaling interactions increase. A sensitivity analysis is presented to highlight the impact due to imperfect coverage of duplex network component or element failures (i.e., correlated failures), to assist in the setting of requirements on NE robustness. A benefit analysis, covering several dimensions of dependability, is used to generate the domain of solutions available to the network architect in terms of network and network element fault tolerance that may be specified to meet the desired signaling quality goals.

  16. Solar-thermal jet pumping for irrigation

    NASA Astrophysics Data System (ADS)

    Clements, L. D.; Dellenback, P. A.; Bell, C. A.

    1980-01-01

    This paper describes a novel concept in solar powered irrigation pumping, gives measured performance data for the pump unit, and projected system performance. The solar-thermal jet pumping concept is centered around a conventional jet eductor pump which is commercially available at low cost. The jet eductor pump is powered by moderate temperature, moderate pressure Refrigerant-113 vapor supplied by a concentrating solar collector field. The R-113 vapor is direct condensed by the produced water and the two fluids are separated at the surface. The water goes on to use and the R-113 is repressurized and returned to the solar field. The key issue in the solar-thermal jet eductor concept is the efficiency of pump operation. Performance data from a small scale experimental unit which utilizes an electrically heated boiler in place of the solar field is presented. The solar-thermal jet eductor concept is compared with other solar irrigation concepts and optimal application situations are identified. Though having lower efficiencies than existing Rankine cycle solar-thermal irrigation systems, the mechanical and operational simplicity of this concept make it competitive with other solar powered irrigation schemes.

  17. Jetting Through the Primordial Universe

    NASA Astrophysics Data System (ADS)

    Kunnawalkam Elayavalli, Raghav

    Collisions of heavy ion nuclei at relativistic speeds (close to the speed of light), sometimes referred to as the "little bang", can recreate conditions similar to the early universe. This high temperature and very dense form of matter, now known to consist of de-confined quarks and gluons is named the quark gluon plasma (QGP). An early signature of the QGP, both theorized and seen in experiments, was the aspect of "jet quenching" and understanding that phenomenon will be the main focus of this thesis. The concept behind quenching is that a high energetic quark or gluon jet undergoes significant energy loss due to the overall structure modifications related to its fragmentation and radiation patterns as it traverses the medium. The term jet, parameterized by a fixed lateral size or the jet radius, represents the collimated spray of particles arising from an initial parton. In this thesis, Run1 experimental data from pp and heavy ion collisions at the CERN LHC is analyzed with the CMS detector. Analysis steps involved in the measurement of the inclusive jet cross section in pp, pPb and PbPb systems are outlined in detail. The pp jet cross section is compared with next to leading order theoretical calculations supplemented with non perturbative corrections for three different jet radii highlighting better comparisons for larger radii jets. Measurement of the jet yield followed by the nuclear modification factors in proton-lead at 5.02 TeV and lead-lead collisions at 2.76 TeV are presented. Since pp data at 5.02 TeV was not available in Run1, an extrapolation method is performed to derive a reference pp spectra. A new data driven technique is introduced to estimate and correct for the fake jet contribution in PbPb for low transverse momenta jets. The nuclear modification factors studied in this thesis show jet quenching to be attributed to final state effects, have a strong correlation to the event centrality, a weak inverse correlation to the jet transverse momenta

  18. Jet Precession Driven by a Supermassive Black Hole Binary System in the BL Lac Object PG 1553+113

    NASA Astrophysics Data System (ADS)

    Caproni, Anderson; Abraham, Zulema; Motter, Juliana Cristina; Monteiro, Hektor

    2017-12-01

    The recent discovery of a roughly simultaneous periodic variability in the light curves of the BL Lac object PG 1553+113 at several electromagnetic bands represents the first case of such odd behavior reported in the literature. Motivated by this, we analyzed 15 GHz interferometric maps of the parsec-scale radio jet of PG 1553+113 to verify the presence of a possible counterpart of this periodic variability. We used the Cross-entropy statistical technique to obtain the structural parameters of the Gaussian components present in the radio maps of this source. We kinematically identified seven jet components formed coincidentally with flare-like features seen in the γ-ray light curve. From the derived jet component positions in the sky plane and their kinematics (ejection epochs, proper motions, and sky position angles), we modeled their temporal changes in terms of a relativistic jet that is steadily precessing in time. Our results indicate a precession period in the observer’s reference frame of 2.24 ± 0.03 years, compatible with the periodicity detected in the light curves of PG 1553+113. However, the maxima of the jet Doppler boosting factor are systematically delayed relative to the peaks of the main γ-ray flares. We propose two scenarios that could explain this delay, both based on the existence of a supermassive black hole binary system in PG 1553+113. We estimated the characteristics of this putative binary system that also would be responsible for driving the inferred jet precession.

  19. Small Subunits of Serine Palmitoyltransferase (ssSPTs) and Their Physiological Roles

    DTIC Science & Technology

    2014-02-12

    showing that organisms also have unique sphingoid base chain lengths. In insects, such as Drosophila melanogaster , the predominant chain lengths of the ... Drosophila melanogaster mutant defective in male meiotic cytokinesis (‘Ghiberti’) has a mutation in a gene with low homology to the ssSPT subunits of...INTRODUCTION: Sphingolipid metabolism in Drosophila melanogaster (fly) is an active area of research. It is a good model system to study the roles of

  20. Middle Level SS&C Energy Series.

    ERIC Educational Resources Information Center

    Crow, Linda W.; Aldridge, Bill G.

    The project on Scope Sequence and Coordination of Secondary School Science (SS&C) was initiated by the National Science Teachers Association (NSTA) and recommends that all students study science every year and advocates carefully sequenced, well-coordinated instruction in biology, chemistry, earth/space science, and physics. This document…

  1. Spa47 is an oligomerization-activated type three secretion system (T3SS) ATPase from Shigella flexneri.

    PubMed

    Burgess, Jamie L; Jones, Heather B; Kumar, Prashant; Toth, Ronald T; Middaugh, C Russell; Antony, Edwin; Dickenson, Nicholas E

    2016-05-01

    Gram-negative pathogens often use conserved type three secretion systems (T3SS) for virulence. The Shigella type three secretion apparatus (T3SA) penetrates the host cell membrane and provides a unidirectional conduit for injection of effectors into host cells. The protein Spa47 localizes to the base of the apparatus and is speculated to be an ATPase that provides the energy for T3SA formation and secretion. Here, we developed an expression and purification protocol, producing active Spa47 and providing the first direct evidence that Spa47 is a bona fide ATPase. Additionally, size exclusion chromatography and analytical ultracentrifugation identified multiple oligomeric species of Spa47 with the largest greater than 8 fold more active for ATP hydrolysis than the monomer. An ATPase inactive Spa47 point mutant was then engineered by targeting a conserved Lysine within the predicted Walker A motif of Spa47. Interestingly, the mutant maintained a similar oligomerization pattern as active Spa47, but was unable to restore invasion phenotype when used to complement a spa47 null S. flexneri strain. Together, these results identify Spa47 as a Shigella T3SS ATPase and suggest that its activity is linked to oligomerization, perhaps as a regulatory mechanism as seen in some related pathogens. Additionally, Spa47 catalyzed ATP hydrolysis appears to be essential for host cell invasion, providing a strong platform for additional studies dissecting its role in virulence and providing an attractive target for anti-infective agents. © 2016 The Protein Society.

  2. Jet Surface Interaction Scrubbing Noise from High Aspect-Ratio Rectangular Jets

    NASA Technical Reports Server (NTRS)

    Khavaran, Abbas; Bozak, Richard F.

    2015-01-01

    Concepts envisioned for the future of civil air transport consist of unconventional propulsion systems in the close proximity of the airframe. Distributed propulsion system with exhaust configurations that resemble a high aspect ratio rectangular jet are among geometries of interest. Nearby solid surfaces could provide noise shielding for the purpose of reduced community noise. Interaction of high-speed jet exhaust with structure could also generate new sources of sound as a result of flow scrubbing past the structure, and or scattered noise from sharp edges. The present study provides a theoretical framework to predict the scrubbing noise component from a high aspect ratio rectangular exhaust in proximity of a solid surface. The analysis uses the Greens function (GF) to the variable density Pridmore-Brown equation in a transversely sheared mean flow. Sources of sound are defined as the auto-covariance function of second-rank velocity fluctuations in the jet plume, and are modeled using a RANS-based acoustic analogy approach. Acoustic predictions are presented in an 8:1 aspect ratio rectangular exhaust at three subsonic Mach numbers. The effect of nearby surface on the scrubbing noise component is shown on both reflected and shielded sides of the plate.

  3. Previously unknown and highly divergent ssDNA viruses populate the oceans.

    PubMed

    Labonté, Jessica M; Suttle, Curtis A

    2013-11-01

    Single-stranded DNA (ssDNA) viruses are economically important pathogens of plants and animals, and are widespread in oceans; yet, the diversity and evolutionary relationships among marine ssDNA viruses remain largely unknown. Here we present the results from a metagenomic study of composite samples from temperate (Saanich Inlet, 11 samples; Strait of Georgia, 85 samples) and subtropical (46 samples, Gulf of Mexico) seawater. Most sequences (84%) had no evident similarity to sequenced viruses. In total, 608 putative complete genomes of ssDNA viruses were assembled, almost doubling the number of ssDNA viral genomes in databases. These comprised 129 genetically distinct groups, each represented by at least one complete genome that had no recognizable similarity to each other or to other virus sequences. Given that the seven recognized families of ssDNA viruses have considerable sequence homology within them, this suggests that many of these genetic groups may represent new viral families. Moreover, nearly 70% of the sequences were similar to one of these genomes, indicating that most of the sequences could be assigned to a genetically distinct group. Most sequences fell within 11 well-defined gene groups, each sharing a common gene. Some of these encoded putative replication and coat proteins that had similarity to sequences from viruses infecting eukaryotes, suggesting that these were likely from viruses infecting eukaryotic phytoplankton and zooplankton.

  4. Shaping planetary nebulae with jets in inclined triple stellar systems

    NASA Astrophysics Data System (ADS)

    Akashi, Muhammad; Soker, Noam

    2017-10-01

    We conduct three-dimensional hydrodynamical simulations of two opposite jets launched obliquely to the orbital plane around an asymptotic giant branch (AGB) star and within its dense wind, and demonstrate the formation of a `messy' planetary nebula (PN), namely, a PN lacking any type of symmetry (highly irregular). In building the initial conditions we assume that a tight binary system orbits the AGB star, and that the orbital plane of the tight binary system is inclined to the orbital plane of binary system and the AGB star. We further assume that the accreted mass onto the tight binary system forms an accretion disk around one of the stars, and that the plane of the disk is in between the two orbital planes. The highly asymmetrical lobes that we obtain support the notion that messy PNe might be shaped by triple stellar systems.

  5. Toward Active Control of Noise from Hot Supersonic Jets

    DTIC Science & Technology

    2012-07-24

    1.5 heated jet simulated by way of LES. spreading angles of the jet which were determined from prelimi- nary LES computations performed by CRAFT Tech...system allowed time-resolved and high dynamic range measurements to be ob- tained for a heated , supersonic jet. Each component of the system is...independently operated, temporal spacing between frames is variable and can be set in an asynchronous fashion. Such flexibility even allows eight

  6. Experimental evidence of multimaterial jet formation with lasers

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nicolaie, Ph.; Stenz, C.; Tikhonchuk, V.

    2010-11-15

    Laser-produced multimaterial jets have been investigated at the Prague Asterix Laser System laser [K. Jungwirth et al., Phys. Plasmas 8, 2495 (2001)]. The method of jet production is based on the laser-plasma ablation process and proved to be easy to set up and robust. The possibility of multimaterial laboratory jet production is demonstrated and complex hydrodynamic flows in the jet body are obtained. Two complementary diagnostics in the optical ray and x-ray ranges provide detailed information about jet characteristics. The latter are in agreement with estimates and two-dimensional radiation hydrodynamic simulation results. The experiment provides a proof of principle thatmore » a velocity field could be produced and controlled in the jet body. It opens a possibility of astrophysical jet structure modeling in laboratory.« less

  7. The Impact of Subsonic Twin Jets on Airport Noise

    NASA Technical Reports Server (NTRS)

    Bozak, Richard, F.

    2012-01-01

    Subsonic and supersonic aircraft concepts proposed through NASA s Fundamental Aeronautics Program have multiple engines mounted near one another. Engine configurations with multiple jets introduce an asymmetry to the azimuthal directivity of the jet noise. Current system noise predictions add the jet noise from each jet incoherently, therefore, twin jets are estimated by adding 3 EPNdB to the far-field noise radiated from a single jet. Twin jet effects have the ability to increase or decrease the radiated noise to different azimuthal observation locations. Experiments have shown that twin jet effects are reduced with forward flight and increasing spacings. The current experiment investigates the impact of spacing, and flight effects on airport noise for twin jets. Estimating the jet noise radiated from twin jets as that of a single jet plus 3 EPNdB may be sufficient for horizontal twin jets with an s/d of 4.4 and 5.5, where s is the center-to-center spacing and d is the jet diameter. However, up to a 3 EPNdB error could be present for jet spacings with an s/d of 2.6 and 3.2.

  8. Experimental study of elliptical jet from sub to supercritical conditions

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Muthukumaran, C. K.; Vaidyanathan, Aravind, E-mail: aravind7@iist.ac.in

    2014-04-15

    The jet mixing at supercritical conditions involves fluid dynamics as well as thermodynamic phenomena. All the jet mixing studies at critical conditions to the present date have focused only on axisymmetric jets. When the liquid jet is injected into supercritical environment, the thermodynamic transition could be well understood by considering one of the important fluid properties such as surface tension since it decides the existence of distinct boundary between the liquid and gaseous phase. It is well known that an elliptical liquid jet undergoes axis-switching phenomena under atmospheric conditions due to the presence of surface tension. The experimental investigations weremore » carried out with low speed elliptical jet under supercritical condition. Investigation of the binary component system with fluoroketone jet and N{sub 2} gas as environment shows that the surface tension force dominates for a large downstream distance, indicating delayed thermodynamic transition. The increase in pressure to critical state at supercritical temperature is found to expedite the thermodynamic transition. The ligament like structures has been observed rather than droplets for supercritical pressures. However, for the single component system with fluoroketone jet and fluoroketone environment shows that the jet disintegrates into droplets as it is subjected to the chamber conditions even for the subcritical pressures and no axis switching phenomenon is observed. For a single component system, as the pressure is increased to critical state, the liquid jet exhibits gas-gas like mixing behavior and that too without exhibiting axis-switching behavior.« less

  9. Far Noise Field of Air Jets and Jet Engines

    NASA Technical Reports Server (NTRS)

    Callaghan, Edmund E; Coles, Willard D

    1957-01-01

    An experimental investigation was conducted to study and compare the acoustic radiation of air jets and jet engines. A number of different nozzle-exit shapes were studied with air jets to determine the effect of exit shape on noise generation. Circular, square, rectangular, and elliptical convergent nozzles and convergent-divergent and plug nozzles were investigated. The spectral distributions of the sound power for the engine and the air jet were in good agreement for the case where the engine data were not greatly affected by reflection or jet interference effects. Such power spectra for a subsonic or slightly choked engine or air jet show that the peaks of the spectra occur at a Strouhal number of 0.3.

  10. Flow-field characteristics of high-temperature annular buoyant jets and their development laws influenced by ventilation system.

    PubMed

    Wang, Yi; Huang, Yanqiu; Liu, Jiaping; Wang, Hai; Liu, Qiuhan

    2013-01-01

    The flow-field characteristics of high-temperature annular buoyant jets as well as the development laws influenced by ventilation system were studied using numerical methods to eliminate the pollutants effectively in this paper. The development laws of high-temperature annular buoyant jets were analyzed and compared with previous studies, including radial velocity distribution, axial velocity and temperature decay, reattachment position, cross-section diameter, volumetric flow rate, and velocity field characteristics with different pressures at the exhaust hood inlet. The results showed that when the ratio of outer diameter to inner diameter of the annulus was smaller than 5/2, the flow-field characteristics had significant difference compared to circular buoyant jets with the same outer diameter. For similar diameter ratios, reattachment in this paper occurred further downstream in contrast to previous study. Besides, the development laws of volumetric flow rate and cross-section diameter were given with different initial parameters. In addition, through analyzing air distribution characteristics under the coupling effect of high-temperature annular buoyant jets and ventilation system, it could be found that the position where maximum axial velocity occurred was changing gradually when the pressure at the exhaust hood inlet changed from 0 Pa to -5 Pa.

  11. Flow-Field Characteristics of High-Temperature Annular Buoyant Jets and Their Development Laws Influenced by Ventilation System

    PubMed Central

    Liu, Jiaping; Wang, Hai; Liu, Qiuhan

    2013-01-01

    The flow-field characteristics of high-temperature annular buoyant jets as well as the development laws influenced by ventilation system were studied using numerical methods to eliminate the pollutants effectively in this paper. The development laws of high-temperature annular buoyant jets were analyzed and compared with previous studies, including radial velocity distribution, axial velocity and temperature decay, reattachment position, cross-section diameter, volumetric flow rate, and velocity field characteristics with different pressures at the exhaust hood inlet. The results showed that when the ratio of outer diameter to inner diameter of the annulus was smaller than 5/2, the flow-field characteristics had significant difference compared to circular buoyant jets with the same outer diameter. For similar diameter ratios, reattachment in this paper occurred further downstream in contrast to previous study. Besides, the development laws of volumetric flow rate and cross-section diameter were given with different initial parameters. In addition, through analyzing air distribution characteristics under the coupling effect of high-temperature annular buoyant jets and ventilation system, it could be found that the position where maximum axial velocity occurred was changing gradually when the pressure at the exhaust hood inlet changed from 0 Pa to −5 Pa. PMID:24000278

  12. Characterization of Circular ssDNA Viruses within the Echinoderm Nanobiome

    NASA Astrophysics Data System (ADS)

    Jackson, E.; Bistolas, K. S.; Hewson, I.

    2016-02-01

    Viral metagenomics has revealed a great diversity and presence of circular single-stranded(ss) DNA viruses most similar to the viral family Circoviridae in various environments both ambient and host. These viruses are an emerging paradigm in viral discovery amongst aquatic invertebrates mainly from the sub-phlya Crustacea and to a lesser extent the phylum Echinodermata. This parasite-host relationship is furthered here with the discovery of circo-like viruses extracted from the tissue of members from the family Holothuroidea (sea cucumbers). Verification and presence of these viruses within the tissue of the host was confirmed through rigorous genome architecture screening and PCR amplification of the rep gene from unamplified viral DNA extracts. Phylogenetic analysis of the rep gene reveals high similarity to circular ssDNA viruses from environmental metagenomic surveys of marine habitats. The significance of these findings is changing the perception and understanding of circular ssDNA viruses by broadening the known host range and blurring certain defining characteristics established by their pathogenic counterparts. Aside from discover and characterization, the potential ecological impacts of ssDNA viruses upon their host remains relatively unknown and further investigations should aim to determine the pathology, route of infection, and ecological implications of viral infection.

  13. Impact of the Arizona NExSS Winter School on Interdisciplinary Knowledge and Attitudes

    NASA Astrophysics Data System (ADS)

    Huff, Cierra; Burnam-Fink, Michael; Desch, Steven; Apai, Dániel

    2018-01-01

    The Nexus for Exoplanet System Science (NExSS) is a NASA-funded research coordination network whose focus is on investigating exoplanet diversity and devising strategies for searching for life on exoplanets. The fields of exoplanets and astrobiology are inherently highly interdisciplinary. Progress in these fields demands that researchers with various scientific backgrounds understand the issues and techniques of allied fields of study, including the tools and approaches used to solve different problems, as well as their limitations.In 2016, the NExSS teams at Arizona State University (ASU) and University of Arizona (UA) hosted 32 graduate students and postdoctoral researchers from various scientific backgrounds for one week at the Arizona NExSS Winter School. To bridge the gaps between fields and promote interdisciplinarity, students participated in lessons, field trips, hands-on activities, and a capstone proposal-writing activity. To assess the impact of the School on knowledge and attitudes about other fields, we administered a pre- and post-School questionnaire designed using the Impact Analysis Method of Davis & Scalice (2015).The results show that all participants gained knowledge at the School, especially in areas outside their primary field of study. The questionnaire revealed interesting differences in attitudes as well. When asked whether the geochemistry of Earth without life is predictable, planetary scientists were more likely than average to say yes, and geologists were more likely than average to say no. Their attitudes had converged after participation in the School. These results demonstrate that the Arizona NExSS Winter School was impactful not just in the knowledge gained, but in the interdisciplinary attitudes of students.

  14. Coordinated X-ray, ultraviolet and optical observations of AM Herculis, U Geminorum, and SS Cygni

    NASA Technical Reports Server (NTRS)

    Fabbiano, G.; Hartmann, L.; Raymond, J.; Branduardi-Raymont, G.; Matilsky, T.; Steiner, J.

    1981-01-01

    Simultaneous and quasi-simultaneous optical, UV and X-ray observations of the accreting degenerate dwarf stars AM Herculis, U Geminorum and SS Cygni are reported. The observations were obtained in March 1979, by instruments on board the Einstein Observatory and the IUE satellite, and optical properties were monitored on the ground. AM Her was found to be in a high state at the time of the observations, while SS Cyg and U Gem appeared to be in the optical low state. The presence of a strong UV excess is found in SS Cyg, U Gem and AM Her, which most likely originates from the boundary of the accretion disk in U Gem. The observed excess, with a blackbody component greater than 10 eV, is noted to be inconsistent with standard accretion disk and column models. It is suggested that nuclear burning at the surface of the white dwarf may be responsible for the excess UV flux in the three systems, with differences in spectral distributions resulting from different levels of magnetic field intensity and accretion rate.

  15. GPR54 and KiSS-1: role in the regulation of puberty and reproduction.

    PubMed

    Kuohung, Wendy; Kaiser, Ursula B

    2006-12-01

    The finding of inactivating mutations in GPR54 in IHH patients and the lack of reproductive maturation of the GPR54 null mouse have uncovered a previously unrecognized role for GPR54 and KiSS-1 in the physiologic regulation of puberty and reproduction. This newly identified function for GPR54 and its cognate ligand, kisspeptin, has led to additional studies that have localized GPR54 and KiSS-1 mRNA in the hypothalamus, colocalized GPR54 in GnRH neurons, demonstrated GnRH-dependent activation of LH and FSH release by kisspeptin, and shown increased hypothalamic KiSS-1 and GPR54 mRNA levels at the time of puberty. Taken together, these findings establish the role of the kisspeptin-GPR54 system in the stimulation of GnRH neurons during puberty. The mechanisms by which kisspeptin activates GnRH release, as well as the trigger for this pathway at the onset of puberty, are yet to be elucidated. In the future, modulators of GPR54 activity, including kisspeptin, may prove valuable in clinical applications in the fields of both cancer therapy and reproductive medicine.

  16. Combining metric episodes with semantic event concepts within the Symbolic and Sub-Symbolic Robotics Intelligence Control System (SS-RICS)

    NASA Astrophysics Data System (ADS)

    Kelley, Troy D.; McGhee, S.

    2013-05-01

    This paper describes the ongoing development of a robotic control architecture that inspired by computational cognitive architectures from the discipline of cognitive psychology. The Symbolic and Sub-Symbolic Robotics Intelligence Control System (SS-RICS) combines symbolic and sub-symbolic representations of knowledge into a unified control architecture. The new architecture leverages previous work in cognitive architectures, specifically the development of the Adaptive Character of Thought-Rational (ACT-R) and Soar. This paper details current work on learning from episodes or events. The use of episodic memory as a learning mechanism has, until recently, been largely ignored by computational cognitive architectures. This paper details work on metric level episodic memory streams and methods for translating episodes into abstract schemas. The presentation will include research on learning through novelty and self generated feedback mechanisms for autonomous systems.

  17. Linearized unsteady jet analysis

    NASA Technical Reports Server (NTRS)

    Viets, H.; Piatt, M.

    1979-01-01

    The introduction of a time dependency into a jet flow to change the rate at which it mixes with a coflowing stream or ambient condition is investigated. The advantages and disadvantages of the unsteady flow are discussed in terms of steady state mass and momentum transfer. A linear system which is not limited by frequency constraints and evolves through a simplification of the equations of motion is presented for the analysis of the unsteady flow field generated by the time dependent jet.

  18. Stretched Inertial Jets

    NASA Astrophysics Data System (ADS)

    Ghabache, Elisabeth; Antkowiak, Arnaud; Seon, Thomas; Villermaux, Emmanuel

    2015-11-01

    Liquid jets often arise as short-lived bursting liquid flows. Cavitation or impact-driven jets, bursting champagne bubbles, shaped-charge jets, ballistospores or drop-on-demand inkjet printing are a few examples where liquid jets are suddenly released. The trademark of all these discharge jets is the property of being stretched, due to the quenching injection. the present theoretical and experimental investigation, the structure of the jet flow field will be unraveled experimentally for a few emblematic occurrences of discharge jets. Though the injection markedly depends on each flow configuration, the jet velocity field will be shown to be systematically and rapidly attracted to the universal stretching flow z/t. The emergence of this inertial attractor actually only relies on simple kinematic ingredients, and as such is fairly generic. The universality of the jet velocity structure will be discussed.

  19. Supersonic Injection of Aerated Liquid Jet

    NASA Astrophysics Data System (ADS)

    Choudhari, Abhijit; Sallam, Khaled

    2016-11-01

    A computational study of the exit flow of an aerated two-dimensional jet from an under-expanded supersonic nozzle is presented. The liquid sheet is operating within the annular flow regime and the study is motivated by the application of supersonic nozzles in air-breathing propulsion systems, e.g. scramjet engines, ramjet engines and afterburners. The simulation was conducted using VOF model and SST k- ω turbulence model. The test conditions included: jet exit of 1 mm and mass flow rate of 1.8 kg/s. The results show that air reaches transonic condition at the injector exit due to the Fanno flow effects in the injector passage. The aerated liquid jet is alternately expanded by Prandtl-Meyer expansion fan and compressed by oblique shock waves due to the difference between the back (chamber) pressure and the flow pressure. The process then repeats itself and shock (Mach) diamonds are formed at downstream of injector exit similar to those typical of exhaust plumes of propulsion system. The present results, however, indicate that the flow field of supersonic aerated liquid jet is different from supersonic gas jets due to the effects of water evaporation from the liquid sheet. The contours of the Mach number, static pressure of both cases are compared to the theory of gas dynamics.

  20. Shaping planetary nebulae with jets in inclined triple stellar systems

    NASA Astrophysics Data System (ADS)

    Akashi, Muhammad; Soker, Noam

    2017-08-01

    We conduct three-dimensional hydrodynamical simulations of two opposite jets launched obliquely to the orbital plane around an asymptotic giant branch (AGB) star and within its dense wind, and demonstrate the formation of a 'messy' planetary nebula (PN), namely a PN lacking any type of symmetry (I.e. highly irregular). In building the initial conditions, we assume that a tight binary system orbits the AGB star and that the orbital plane of the tight binary system is inclined to the orbital plane of the binary system and the AGB star (the triple system plane). We further assume that the accreted mass on to the tight binary system forms an accretion disc around one of the stars and that the plane of the disc is tilted to the orbital plane of the triple system. The highly asymmetrical and filamentary structures that we obtain support the notion that messy PNe might be shaped by triple stellar systems.

  1. Plasma Jet Simulations Using a Generalized Ohm's Law

    NASA Technical Reports Server (NTRS)

    Ebersohn, Frans; Shebalin, John V.; Girimaji, Sharath S.

    2012-01-01

    Plasma jets are important physical phenomena in astrophysics and plasma propulsion devices. A currently proposed dual jet plasma propulsion device to be used for ISS experiments strongly resembles a coronal loop and further draws a parallel between these physical systems [1]. To study plasma jets we use numerical methods that solve the compressible MHD equations using the generalized Ohm s law [2]. Here, we will discuss the crucial underlying physics of these systems along with the numerical procedures we utilize to study them. Recent results from our numerical experiments will be presented and discussed.

  2. Liquid and gelled sprays for mixing hypergolic propellants using an impinging jet injection system

    NASA Astrophysics Data System (ADS)

    James, Mark D.

    The characteristics of sprays produced by liquid rocket injectors are important in understanding rocket engine ignition and performance. The includes, but is not limited to, drop size distribution, spray density, drop velocity, oscillations in the spray, uniformity of mixing between propellants, and the spatial distribution of drops. Hypergolic ignition and the associated ignition delay times are also important features in rocket engines, providing high reliability and simplicity of the ignition event. The ignition delay time is closely related to the level and speed of mixing between a hypergolic fuel and oxidizer, which makes the injection method and conditions crucial in determining the ignition performance. Although mixing and ignition of liquid hypergolic propellants has been studied for many years, the processes for injection, mixing, and ignition of gelled hypergolic propellants are less understood. Gelled propellants are currently under investigation for use in rocket injectors to combine the advantages of solid and liquid propellants, although not without their own difficulties. A review of hypergolic ignition has been conducted for selected propellants, and methods for achieving ignition have been established. This research is focused on ignition using the liquid drop-on-drop method, as well as the doublet impinging jet injector. The events leading up to ignition, known as pre-ignition stage are discussed. An understanding of desirable ignition and combustion performance requires a study of the effects of injection, temperature, and ambient pressure conditions. A review of unlike-doublet impinging jet injection mixing has also been conducted. This includes mixing factors in reactive and non-reactive sprays. Important mixing factors include jet momentum, jet diameter and length, impingement angle, mass distribution, and injector configuration. An impinging jet injection system is presented using an electro-mechanically driven piston for injecting liquid

  3. LoCuSS: Testing hydrostatic equilibrium in galaxy clusters

    NASA Astrophysics Data System (ADS)

    Smith, G. P.; Mazzotta, P.; Okabe, N.; Ziparo, F.; Mulroy, S. L.; Babul, A.; Finoguenov, A.; McCarthy, I. G.; Lieu, M.; Bahé, Y. M.; Bourdin, H.; Evrard, A. E.; Futamase, T.; Haines, C. P.; Jauzac, M.; Marrone, D. P.; Martino, R.; May, P. E.; Taylor, J. E.; Umetsu, K.

    2016-02-01

    We test the assumption of hydrostatic equilibrium in an X-ray luminosity selected sample of 50 galaxy clusters at 0.15 < z < 0.3 from the Local Cluster Substructure Survey (LoCuSS). Our weak-lensing measurements of M500 control systematic biases to sub-4 per cent, and our hydrostatic measurements of the same achieve excellent agreement between XMM-Newton and Chandra. The mean ratio of X-ray to lensing mass for these 50 clusters is β_X= 0.95± 0.05, and for the 44 clusters also detected by Planck, the mean ratio of Planck mass estimate to LoCuSS lensing mass is β_P= 0.95± 0.04. Based on a careful like-for-like analysis, we find that LoCuSS, the Canadian Cluster Comparison Project, and Weighing the Giants agree on β_P ≃ 0.9-0.95 at 0.15 < z < 0.3. This small level of hydrostatic bias disagrees at ˜5σ with the level required to reconcile Planck cosmology results from the cosmic microwave background and galaxy cluster counts.

  4. AGN feedback compared: jets versus radiation

    NASA Astrophysics Data System (ADS)

    Cielo, Salvatore; Bieri, Rebekka; Volonteri, Marta; Wagner, Alexander Y.; Dubois, Yohan

    2018-06-01

    Feedback by active galactic nuclei (AGNs) is often divided into quasar and radio mode, powered by radiation or radio jets, respectively. Both are fundamental in galaxy evolution, especially in late-type galaxies, as shown by cosmological simulations and observations of jet-ISM (interstellar medium) interactions in these systems. We compare AGN feedback by radiation and by collimated jets through a suite of simulations, in which a central AGN interacts with a clumpy, fractal galactic disc. We test AGNs of 1043 and 1046 erg s-1, considering jets perpendicular or parallel to the disc. Mechanical jets drive the more powerful outflows, exhibiting stronger mass and momentum coupling with the dense gas, while radiation heats and rarefies the gas more. Radiation and perpendicular jets evolve to be quite similar in outflow properties and effect on the cold ISM, while inclined jets interact more efficiently with all the disc gas, removing the densest 20 {per cent} in 20 Myr, and thereby reducing the amount of cold gas available for star formation. All simulations show small-scale inflows of 0.01-0.1 M⊙ yr-1, which can easily reach down to the Bondi radius of the central supermassive black hole (especially for radiation and perpendicular jets), implying that AGNs modulate their own duty cycle in a feedback/feeding cycle.

  5. Factorization for jet radius logarithms in jet mass spectra at the LHC

    DOE PAGES

    Kolodrubetz, Daniel W.; Pietrulewicz, Piotr; Stewart, Iain W.; ...

    2016-12-14

    To predict the jet mass spectrum at a hadron collider it is crucial to account for the resummation of logarithms between the transverse momentum of the jet and its invariant mass m J . For small jet areas there are additional large logarithms of the jet radius R, which affect the convergence of the perturbative series. We present an analytic framework for exclusive jet production at the LHC which gives a complete description of the jet mass spectrum including realistic jet algorithms and jet vetoes. It factorizes the scales associated with m J , R, and the jet veto, enablingmore » in addition the systematic resummation of jet radius logarithms in the jet mass spectrum beyond leading logarithmic order. We discuss the factorization formulae for the peak and tail region of the jet mass spectrum and for small and large R, and the relations between the different regimes and how to combine them. Regions of experimental interest are classified which do not involve large nonglobal logarithms. We also present universal results for nonperturbative effects and discuss various jet vetoes.« less

  6. Multiphase flow of miscible liquids: jets and drops

    NASA Astrophysics Data System (ADS)

    Walker, Travis W.; Logia, Alison N.; Fuller, Gerald G.

    2015-05-01

    Drops and jets of liquids that are miscible with the surrounding bulk liquid are present in many processes from cleaning surfaces with the aid of liquid soaps to the creation of biocompatible implants for drug delivery. Although the interactions of immiscible drops and jets show similarities to miscible systems, the small, transient interfacial tension associated with miscible systems create distinct outcomes such as intricate droplet shapes and breakup resistant jets. Experiments have been conducted to understand several basic multiphase flow problems involving miscible liquids. Using high-speed imaging of the morphological evolution of the flows, we have been able to show that these processes are controlled by interfacial tensions. Further multiphase flows include investigating miscible jets, which allow the creation of fibers from inelastic materials that are otherwise difficult to process due to capillary breakup. This work shows that stabilization from the diminishing interfacial tensions of the miscible jets allows various elongated morphologies to be formed.

  7. Python based integration of GEM detector electronics with JET data acquisition system

    NASA Astrophysics Data System (ADS)

    Zabołotny, Wojciech M.; Byszuk, Adrian; Chernyshova, Maryna; Cieszewski, Radosław; Czarski, Tomasz; Dalley, Simon; Hogben, Colin; Jakubowska, Katarzyna L.; Kasprowicz, Grzegorz; Poźniak, Krzysztof; Rzadkiewicz, Jacek; Scholz, Marek; Shumack, Amy

    2014-11-01

    This paper presents the system integrating the dedicated measurement and control electronic systems for Gas Electron Multiplier (GEM) detectors with the Control and Data Acquisition system (CODAS) in the JET facility in Culham, England. The presented system performs the high level procedures necessary to calibrate the GEM detector and to protect it against possible malfunctions or dangerous changes in operating conditions. The system also allows control of the GEM detectors from CODAS, setting of their parameters, checking their state, starting the plasma measurement and to reading the results. The system has been implemented using the Python language, using the advanced libraries for implementation of network communication protocols, for object based hardware management and for data processing.

  8. Synergistic Protective Effects of Mitochondrial Division Inhibitor 1 and Mitochondria-Targeted Small Peptide SS31 in Alzheimer's Disease.

    PubMed

    Reddy, P Hemachandra; Manczak, Maria; Yin, XiangLing; Reddy, Arubala P

    2018-01-01

    The purpose of our study was to determine the synergistic protective effects of mitochondria-targeted antioxidant SS31 and mitochondria division inhibitor 1 (Mdivi1) in Alzheimer's disease (AD). Using biochemical methods, we assessed mitochondrial function by measuring the levels of hydrogen peroxide, lipid peroxidation, cytochrome c oxidase activity, mitochondrial ATP, and GTPase Drp1 enzymatic activity in mutant AβPP cells. Using biochemical methods, we also measured cell survival and apoptotic cell death. Amyloid-β (Aβ) levels were measured using sandwich ELISA, and using real-time quantitative RT-PCR, we assessed mtDNA (mtDNA) copy number in relation to nuclear DNA (nDNA) in all groups of cells. We found significantly reduced levels of Aβ40 and Aβ42 in mutant AβPP cells treated with SS31, Mdivi1, and SS31+Mdivi1, and the reduction of Aβ42 levels were much higher in SS31+Mdivi1 treated cells than individual treatments of SS31 and Mdivi1. The levels of mtDNA copy number and cell survival were significantly increased in SS31, Mdivi1, and SS31+Mdivi1 treated mutant AβPP cells; however, the increased levels of mtDNA copy number and cell survival were much higher in SS31+Mdivi1 treated cells than individual treatments of SS31 and Mdivi1. Mitochondrial dysfunction is significantly reduced in SS31, Mdivi1, and SS31+Mdivi1 treated mutant AβPP cells; however, the reduction is much higher in cells treated with both SS31+Mdvi1. Similarly, GTPase Drp1 activity is reduced in all treatments, but reduced much higher in SS31+Mdivi1 treated cells. These observations strongly suggest that combined treatment of SS31+Mdivi1 is effective than individual treatments of SS31 and Mdivi1. Therefore, we propose that combined treatment of SS31+Mdivi1 is a better therapeutic strategy for AD. Ours is the first study to investigate combined treatment of mitochondria-targeted antioxidant SS31 and mitochondrial division inhibitor 1 in AD neurons.

  9. Fabrication of micro/nano-structures by electrohydrodynamic jet technique

    NASA Astrophysics Data System (ADS)

    Wang, Dazhi; Zhao, Xiaojun; Lin, Yigao; Ren, Tongqun; Liang, Junsheng; Liu, Chong; Wang, Liding

    2017-12-01

    Electrohydrodynamic jet (E-Jet) is an approach to the fabrication of micro/nano-structures by the use of electrical forces. In this process, the liquid is subjected to electrical and mechanical forces to form a liquid jet, which is further disintegrated into droplets. The major advantage of the E-Jet technique is that the sizes of the jet formed can be at the nanoscale far smaller than the nozzle size, which can realize high printing resolution with less risk of nozzle blockage. The E-Jet technique, which mainly includes E-Jet deposition and E-Jet printing, has a wide range of applications in the fabrication of micro/nano-structures for micro/nano-electromechanical system devices. This technique is also considered a micro/nano-fabrication method with a great potential for commercial use. This study mainly reviews the E-Jet deposition/printing fundamentals, fabrication process, and applications.

  10. Evaporation system and method for gas jet deposition of thin film materials

    DOEpatents

    Schmitt, J.J.; Halpern, B.L.

    1994-10-18

    A method and apparatus are disclosed for depositing thin films of materials such as metals, oxides and nitrides at low temperature relies on a supersonic free jet of inert carrier gas to transport vapor species generated from an evaporation source to the surface of a substrate. Film deposition vapors are generated from solid film precursor materials, including those in the form of wires or powders. The vapor from these sources is carried downstream in a low pressure supersonic jet of inert gas to the surface of a substrate where the vapors deposit to form a thin film. A reactant gas can be introduced into the gas jet to form a reaction product with the evaporated material. The substrate can be moved from the gas jet past a gas jet containing a reactant gas in which a discharge has been generated, the speed of movement being sufficient to form a thin film which is chemically composed of the evaporated material and reactant gases. 8 figs.

  11. Evaporation system and method for gas jet deposition of thin film materials

    DOEpatents

    Schmitt, Jerome J.; Halpern, Bret L.

    1994-01-01

    A method and apparatus for depositing thin films of materials such as metals, oxides and nitrides at low temperature relies on a supersonic free jet of inert carrier gas to transport vapor species generated from an evaporation source to the surface of a substrate. Film deposition vapors are generated from solid film precursor materials, including those in the form of wires or powders. The vapor from these sources is carried downstream in a low pressure supersonic jet of inert gas to the surface of a substrate where the vapors deposit to form a thin film. A reactant gas can be introduced into the gas jet to form a reaction product with the evaporated material. The substrate can be moved from the gas jet past a gas jet containing a reactant gas in which a discharge has been generated, the speed of movement being sufficient to form a thin film which is chemically composed of the evaporated material and reactant gases.

  12. New Techniques For The Improvement Of The ICRH System ELM Tolerance On JET

    NASA Astrophysics Data System (ADS)

    Monakhov, I.; Blackman, T.; Walden, A.; Nightingale, M.; Whitehurst, A.; Durodie, F.; Jet Efda Contributors

    2003-12-01

    Two complementary improvements to the ELM tolerance of the existing A2 antennas on JET are being assessed. The use of external conjugate-T matching of straps of adjacent antenna arrays could reduce the VSWR levels at RF amplifier output during fast load perturbations. The scheme under consideration uses coaxial line-stretchers (trombones) for tuning the conjugate-T to low resistive impedance (3-6 Ohm) with subsequent stub/trombone circuit impedance transformation to 30 Ohms. Another technique is to modify the RF plant protection system logic to reduce the high VSWR trip duration to an absolute minimum corresponding to a typical ELM response (˜1-2ms) without compromising the plant safety. Both projects are presently being tested and could increase the average power delivered by RF plant into ELMy plasmas at JET.

  13. SynBioSS designer: a web-based tool for the automated generation of kinetic models for synthetic biological constructs

    PubMed Central

    Weeding, Emma; Houle, Jason

    2010-01-01

    Modeling tools can play an important role in synthetic biology the same way modeling helps in other engineering disciplines: simulations can quickly probe mechanisms and provide a clear picture of how different components influence the behavior of the whole. We present a brief review of available tools and present SynBioSS Designer. The Synthetic Biology Software Suite (SynBioSS) is used for the generation, storing, retrieval and quantitative simulation of synthetic biological networks. SynBioSS consists of three distinct components: the Desktop Simulator, the Wiki, and the Designer. SynBioSS Designer takes as input molecular parts involved in gene expression and regulation (e.g. promoters, transcription factors, ribosome binding sites, etc.), and automatically generates complete networks of reactions that represent transcription, translation, regulation, induction and degradation of those parts. Effectively, Designer uses DNA sequences as input and generates networks of biomolecular reactions as output. In this paper we describe how Designer uses universal principles of molecular biology to generate models of any arbitrary synthetic biological system. These models are useful as they explain biological phenotypic complexity in mechanistic terms. In turn, such mechanistic explanations can assist in designing synthetic biological systems. We also discuss, giving practical guidance to users, how Designer interfaces with the Registry of Standard Biological Parts, the de facto compendium of parts used in synthetic biology applications. PMID:20639523

  14. VMD-SS: A graphical user interface plug-in to calculate the protein secondary structure in VMD program.

    PubMed

    Yahyavi, Masoumeh; Falsafi-Zadeh, Sajad; Karimi, Zahra; Kalatarian, Giti; Galehdari, Hamid

    2014-01-01

    The investigation on the types of secondary structure (SS) of a protein is important. The evolution of secondary structures during molecular dynamics simulations is a useful parameter to analyze protein structures. Therefore, it is of interest to describe VMD-SS (a software program) for the identification of secondary structure elements and its trajectories during simulation for known structures available at the Protein Data Bank (PDB). The program helps to calculate (1) percentage SS, (2) SS occurrence in each residue, (3) percentage SS during simulation, and (4) percentage residues in all SS types during simulation. The VMD-SS plug-in was designed using TCL script and stride to calculate secondary structure features. The database is available for free at http://science.scu.ac.ir/HomePage.aspx?TabID=13755.

  15. FAR-TECH's Nanoparticle Plasma Jet System and its Application to Disruptions, Deep Fueling, and Diagnostics

    NASA Astrophysics Data System (ADS)

    Thompson, J. R.; Bogatu, I. N.; Galkin, S. A.; Kim, J. S.

    2012-10-01

    Hyper-velocity plasma jets have potential applications in tokamaks for disruption mitigation, deep fueling and diagnostics. Pulsed power based solid-state sources and plasma accelerators offer advantages of rapid response and mass delivery at high velocities. Fast response is critical for some disruption mitigation scenario needs, while high velocity is especially important for penetration into tokamak plasma and its confining magnetic field, as in the case of deep fueling. FAR-TECH is developing the capability of producing large-mass hyper-velocity plasma jets. The prototype solid-state source has produced: 1) >8.4 mg of H2 gas only, and 2) >25 mg of H2 and >180 mg of C60 in a H2/C60 gas mixture. Using a coaxial plasma gun coupled to the source, we have successfully demonstrated the acceleration of composite H/C60 plasma jets, with momentum as high as 0.6 g.km/s, and containing an estimated C60 mass of ˜75 mg. We present the status of FAR-TECH's nanoparticle plasma jet system and discuss its application to disruptions, deep fueling, and diagnostics. A new TiH2/C60 solid-state source capable of generating significantly higher quantities of H2 and C60 in <0.5 ms will be discussed.

  16. ICRH system performance during ITER-Like Wall operations at JET and the outlook for DT campaign

    NASA Astrophysics Data System (ADS)

    Monakhov, Igor; Blackman, Trevor; Dumortier, Pierre; Durodié, Frederic; Jacquet, Philippe; Lerche, Ernesto; Noble, Craig

    2017-10-01

    Performance of JET ICRH system since installation of the metal ITER-Like Wall (ILW) has been assessed statistically. The data demonstrate steady increase of the RF power coupled to plasmas over recent years with the maximum pulse-average and peak values exceeding respectively 6MW and 8MW in 2016. Analysis and extrapolation of power capabilities of conventional JET ICRH antennas is provided and key performance-limiting factors are discussed. The RF plant operational frequency options are presented highlighting the issues of efficient ICRH application within a foreseeable range of DT plasma scenarios.

  17. Resonant ion acceleration by plasma jets: Effects of jet breaking and the magnetic-field curvature.

    PubMed

    Artemyev, A V; Vasiliev, A A

    2015-05-01

    In this paper we consider resonant ion acceleration by a plasma jet originating from the magnetic reconnection region. Such jets propagate in the background magnetic field with significantly curved magnetic-field lines. Decoupling of ion and electron motions at the leading edge of the jet results in generation of strong electrostatic fields. Ions can be trapped by this field and get accelerated along the jet front. This mechanism of resonant acceleration resembles surfing acceleration of charged particles at a shock wave. To describe resonant acceleration of ions, we use adiabatic theory of resonant phenomena. We show that particle motion along the curved field lines significantly influences the acceleration rate. The maximum gain of energy is determined by the particle's escape from the system due to this motion. Applications of the proposed mechanism to charged-particle acceleration in the planetary magnetospheres and the solar corona are discussed.

  18. Synthetic Jets in Cross-flow. Part 1; Round Jet

    NASA Technical Reports Server (NTRS)

    Zaman, K. B. M. Q.; Milanovic, Ivana M.

    2003-01-01

    Results of an experimental investigation on synthetic jets from round orifices with and without cross-flow are presented. Jet Reynolds number up to 46,000 with a fully turbulent approach boundary layer, and Stokes number up to 400. are covered. The threshold of stroke length for synthetic jet formation. in the absence of the cross-flow, is found to be Lo /D approximately 0.5. Above Lo /D is approximately 10, the profiles of normalized centerline mean velocity appear to become invariant. It is reasoned that the latter threshold may be related to the phenomenon of saturation of impulsively generated vortices. In the presence of the cross-flow, the penetration height of a synthetic jet is found to depend on the momentum- flux ratio . When this ratio is defined in terms of the maximum jet velocity and the cross-flow velocity. not only all data collapse but also the jet trajectory is predicted well by correlation equation available for steady jets-in-cross-flow. Distributions of mean velocity, streamwise vorticity as well as turbulence intensity for a synthetic jet in cross-flow are found to be similar to those of a steady jet-in-cross-flow. A pair of counter-rotating streamwise vortices, corresponding to the bound vortex pair of the steady case, is clearly observed. Mean velocity distribution exhibits a dome of low momentum fluid pulled up from the boundary layer, and the entire domain is characterized by high turbulence.

  19. Multiple jet study data correlations. [data correlation for jet mixing flow of air jets

    NASA Technical Reports Server (NTRS)

    Walker, R. E.; Eberhardt, R. G.

    1975-01-01

    Correlations are presented which allow determination of penetration and mixing of multiple cold air jets injected normal to a ducted subsonic heated primary air stream. Correlations were obtained over jet-to-primary stream momentum flux ratios of 6 to 60 for locations from 1 to 30 jet diameters downstream of the injection plane. The range of geometric and operating variables makes the correlations relevant to gas turbine combustors. Correlations were obtained for the mixing efficiency between jets and primary stream using an energy exchange parameter. Also jet centerplane velocity and temperature trajectories were correlated and centerplane dimensionless temperature distributions defined. An assumption of a Gaussian vertical temperature distribution at all stations is shown to result in a reasonable temperature field model. Data are presented which allow comparison of predicted and measured values over the range of conditions specified above.

  20. The copolymer P(HEMA-co-SS) binds gluten and reduces immune response in gluten-sensitized mice and human tissues.

    PubMed

    Pinier, Maud; Fuhrmann, Gregor; Galipeau, Heather J; Rivard, Nathalie; Murray, Joseph A; David, Chella S; Drasarova, Hana; Tuckova, Ludmila; Leroux, Jean-Christophe; Verdu, Elena F

    2012-02-01

    Copolymers of hydroxyethyl methacrylate and styrene sulfonate complex with isolated gliadin (the toxic fraction of gluten) and prevent damage to the intestinal barrier in HLA-HCD4/DQ8 mice. We studied the activity toward gluten and hordein digestion and biologic effects of poly(hydroxyethyl methacrylate-co-styrene sulfonate (P(HEMA-co-SS)). We also investigated the effect of gliadin complex formation in intestinal biopsy specimens from patients with celiac disease. We studied the ability of P(HEMA-co-SS) to reduce digestion of wheat gluten and barley hordein into immunotoxic peptides using liquid chromatography-mass spectrometry. The biodistribution and pharmacokinetic profile of orally administered P(HEMA-co-SS) was established in rodents using tritium-labeled polymer. We assessed the capacity of P(HEMA-co-SS) to prevent the immunologic and intestinal effects induced by a gluten-food mixture in gluten-sensitized HLA-HCD4/DQ8 mice after short-term and long-term administration. We measured the effects of gliadin complex formation on cytokine release ex vivo using intestinal biopsy specimens from patients with celiac disease. P(HEMA-co-SS) reduced digestion of wheat gluten and barley hordein in vitro, thereby decreasing formation of toxic peptides associated with celiac disease. After oral administration to rodents, P(HEMA-co-SS) was predominantly excreted in feces, even in the presence of low-grade mucosal inflammation and increased intestinal permeability. In gluten-sensitized mice, P(HEMA-co-SS) reduced paracellular permeability, normalized anti-gliadin immunoglobulin A in intestinal washes, and modulated the systemic immune response to gluten in a food mixture. Furthermore, incubation of P(HEMA-co-SS) with mucosal biopsy specimens from patients with celiac disease showed that secretion of tumor necrosis factor-α was reduced in the presence of partially digested gliadin. The copolymer P(HEMA-co-SS) reduced digestion of wheat gluten and barley hordein and

  1. Fuzzy Evaluating Customer Satisfaction of Jet Fuel Companies

    NASA Astrophysics Data System (ADS)

    Cheng, Haiying; Fang, Guoyi

    Based on the market characters of jet fuel companies, the paper proposes an evaluation index system of jet fuel company customer satisfaction from five dimensions as time, business, security, fee and service. And a multi-level fuzzy evaluation model composing with the analytic hierarchy process approach and fuzzy evaluation approach is given. Finally a case of one jet fuel company customer satisfaction evaluation is studied and the evaluation results response the feelings of the jet fuel company customers, which shows the fuzzy evaluation model is effective and efficient.

  2. Nodding motions of accretion rings and disks - A short-term period in SS 433

    NASA Technical Reports Server (NTRS)

    Katz, J. I.; Anderson, S. F.; Grandi, S. A.; Margon, B.

    1982-01-01

    It is pointed out that accretion disks and rings in mass transfer binaries have been observed spectroscopically and calculated theoretically for many years. The present investigation is partly based on the availability of several years of spectroscopic observations of the Doppler shifts of the moving lines in SS433. A formalism is presented to compute frequencies and amplitudes of short-term 'nodding' motions in precessing accretion disks in close binary systems. This formalism is applied to an analysis of the moving-line Doppler shifts in SS433. The 35d X-ray cycle of Hercules X-1 is also discussed. In the considered model, the companion star exerts a gravitational torque on the disk rim. Averaged over the binary orbit, this yields a steady torque which results in the mean driven counterprecession of the disk.

  3. Boosting jet power in black hole spacetimes.

    PubMed

    Neilsen, David; Lehner, Luis; Palenzuela, Carlos; Hirschmann, Eric W; Liebling, Steven L; Motl, Patrick M; Garrett, Travis

    2011-08-02

    The extraction of rotational energy from a spinning black hole via the Blandford-Znajek mechanism has long been understood as an important component in models to explain energetic jets from compact astrophysical sources. Here we show more generally that the kinetic energy of the black hole, both rotational and translational, can be tapped, thereby producing even more luminous jets powered by the interaction of the black hole with its surrounding plasma. We study the resulting Poynting jet that arises from single boosted black holes and binary black hole systems. In the latter case, we find that increasing the orbital angular momenta of the system and/or the spins of the individual black holes results in an enhanced Poynting flux.

  4. Active Region Jets II: Triggering and Evolution of Violent Jets

    NASA Astrophysics Data System (ADS)

    Sterling, Alphonse C.; Moore, Ronald L.; Falconer, David; Panesar, Navdeep K.; Martinez, Francisco

    2017-08-01

    We study a series of X-ray-bright, rapidly evolving active-region coronal jets outside the leading sunspot of AR 12259, using Hinode/XRT, SDO/AIA and HMI, and IRIS/SJ data. The detailed evolution of such rapidly evolving “violent” jets remained a mystery after our previous investigation of active region jets (Sterling et al. 2016, ApJ, 821, 100). The jets we investigate here erupt from three localized subregions, each containing a rapidly evolving (positive) minority-polarity magnetic-flux patch bathed in a (majority) negative-polarity magnetic-flux background. At least several of the jets begin with eruptions of what appear to be thin (thickness ˜<2‧‧) miniature-filament (minifilament) “strands” from a magnetic neutral line where magnetic flux cancelation is ongoing, consistent with the magnetic configuration presented for coronal-hole jets in Sterling et al. (2015, Nature, 523, 437). For some jets strands are difficult/ impossible to detect, perhaps due to their thinness, obscuration by surrounding bright or dark features, or the absence of erupting cool-material minifilaments in those jets. Tracing in detail the flux evolution in one of the subregions, we find bursts of strong jetting occurring only during times of strong flux cancelation. Averaged over seven jetting episodes, the cancelation rate was ~1.5×10^19 Mx/hr. An average flux of ~5×10^18 Mx canceled prior to each episode, arguably building up ~10^28—10^29 ergs of free magnetic energy per jet. From these and previous observations, we infer that flux cancelation is the fundamental process responsible for the pre-eruption buildup and triggering of at least many jets in active regions, quiet regions, and coronal holes.

  5. A Pseudomonas T6SS effector recruits PQS-containing outer membrane vesicles for iron acquisition

    PubMed Central

    Lin, Jinshui; Zhang, Weipeng; Cheng, Juanli; Yang, Xu; Zhu, Kaixiang; Wang, Yao; Wei, Gehong; Qian, Pei-Yuan; Luo, Zhao-Qing; Shen, Xihui

    2017-01-01

    Iron sequestration by host proteins contributes to the defence against bacterial pathogens, which need iron for their metabolism and virulence. A Pseudomonas aeruginosa mutant lacking all three known iron acquisition systems retains the ability to grow in media containing iron chelators, suggesting the presence of additional pathways involved in iron uptake. Here we screen P. aeruginosa mutants defective in growth in iron-depleted media and find that gene PA2374, proximal to the type VI secretion system H3 (H3-T6SS), functions synergistically with known iron acquisition systems. PA2374 (which we have renamed TseF) appears to be secreted by H3-T6SS and is incorporated into outer membrane vesicles (OMVs) by directly interacting with the iron-binding Pseudomonas quinolone signal (PQS), a cell–cell signalling compound. TseF facilitates the delivery of OMV-associated iron to bacterial cells by engaging the Fe(III)-pyochelin receptor FptA and the porin OprF. Our results reveal links between type VI secretion, cell–cell signalling and classic siderophore receptors for iron acquisition in P. aeruginosa. PMID:28348410

  6. The Effect of Jetting Parameters on the Performance of Droplet Formation for Ink-Jet Rapid Prototyping

    NASA Technical Reports Server (NTRS)

    Helmer, Wayne

    1998-01-01

    Heinzl et al. (1985) reports that experiments in ink-jets to produce drawings or signals occurred as early as 1930. Various companies such as IBM and Pitney-Bowes have conducted extensive studies on these devices for many years. Many such reports are available in such journals as the IBM Journal of Research and Development. While numerous articles have been published on the jetting characteristics of ink and water, the literature is rather limited on fluids such as waxes (Gao & Sonin 1994) or non-water based fluids (Passow, et al. 1993). This present study extends the knowledge base to determine the performance of molten waxes in "ink-jet" type printers for rapid prototyping. The purpose of this research was to qualitatively and quantitatively study the droplet formation of a drop-on-demand ink-jet type nozzle system for rapid prototyping.

  7. Design of experimental setup for supercritical CO2 jet under high ambient pressure conditions

    NASA Astrophysics Data System (ADS)

    Shi, Huaizhong; Li, Gensheng; He, Zhenguo; Wang, Haizhu; Zhang, Shikun

    2016-12-01

    With the commercial extraction of hydrocarbons in shale and tight reservoirs, efficient methods are needed to accelerate developing process. Supercritical CO2 (SC-CO2) jet has been considered as a potential way due to its unique fluid properties. In this article, a new setup is designed for laboratory experiment to research the SC-CO2 jet's characteristics in different jet temperatures, pressures, standoff distances, ambient pressures, etc. The setup is composed of five modules, including SC-CO2 generation system, pure SC-CO2 jet system, abrasive SC-CO2 jet system, CO2 recovery system, and data acquisition system. Now, a series of rock perforating (or case cutting) experiments have been successfully conducted using the setup about pure and abrasive SC-CO2 jet, and the results have proven the great perforating efficiency of SC-CO2 jet and the applications of this setup.

  8. Design of experimental setup for supercritical CO2 jet under high ambient pressure conditions.

    PubMed

    Shi, Huaizhong; Li, Gensheng; He, Zhenguo; Wang, Haizhu; Zhang, Shikun

    2016-12-01

    With the commercial extraction of hydrocarbons in shale and tight reservoirs, efficient methods are needed to accelerate developing process. Supercritical CO 2 (SC-CO 2 ) jet has been considered as a potential way due to its unique fluid properties. In this article, a new setup is designed for laboratory experiment to research the SC-CO 2 jet's characteristics in different jet temperatures, pressures, standoff distances, ambient pressures, etc. The setup is composed of five modules, including SC-CO 2 generation system, pure SC-CO 2 jet system, abrasive SC-CO 2 jet system, CO 2 recovery system, and data acquisition system. Now, a series of rock perforating (or case cutting) experiments have been successfully conducted using the setup about pure and abrasive SC-CO 2 jet, and the results have proven the great perforating efficiency of SC-CO 2 jet and the applications of this setup.

  9. Intra-jet shocks in two counter-streaming, weakly collisional plasma jets

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ryutov, D. D.; Kugland, N. L.; Park, H.-S.

    2012-07-15

    Counterstreaming laser-generated plasma jets can serve as a test-bed for the studies of a variety of astrophysical phenomena, including collisionless shock waves. In the latter problem, the jet's parameters have to be chosen in such a way as to make the collisions between the particles of one jet with the particles of the other jet very rare. This can be achieved by making the jet velocities high and the Coulomb cross-sections correspondingly low. On the other hand, the intra-jet collisions for high-Mach-number jets can still be very frequent, as they are determined by the much lower thermal velocities of themore » particles of each jet. This paper describes some peculiar properties of intra-jet hydrodynamics in such a setting: the steepening of smooth perturbations and shock formation affected by the presence of the 'stiff' opposite flow; the role of a rapid electron heating in shock formation; ion heating by the intrajet shock. The latter effect can cause rapid ion heating which is consistent with recent counterstreaming jet experiments by Ross et al.[Phys. Plasmas 19, 056501 (2012)].« less

  10. Rapid Confined Mixing Using Transverse Jets Part 2: Multiple Jets

    NASA Astrophysics Data System (ADS)

    Forliti, David; Salazar, David

    2012-11-01

    An experimental study has been conducted at the Air Force Research Laboratory at Edwards Air Force Base to investigate the properties of confined mixing devices that employ transverse jets. The experiment considers the mixing of water with a mixture of water and fluorescein, and planar laser induced fluorescence was used to measure instantaneous mixture fraction distributions in the cross section view. Part one of this study presents the scaling law development and results for a single confined transverse jet. Part two will describe the results of configurations including multiple transverse jets. The different regimes of mixing behavior, ranging from under to overpenetration of the transverse jets, are characterized in terms of a new scaling law parameter presented in part one. The level of unmixedness, a primary metric for mixing device performance, is quantified for different jet diameters, number of jets, and relative flow rates. It is apparent that the addition of a second transverse jet provides enhanced scalar uniformity in the main pipe flow cross section compared to a single jet. Three and six jet configurations also provide highly uniform scalar distributions. Turbulent scalar fluctuation intensities, spectral features, and spatial eigenfunctions using the proper orthogonal decomposition will be presented. Distribution A: Public Release, Public Affairs Clearance Number: 12656.

  11. Turbulence measurements in axisymmetric jets of air and helium. I - Air jet. II - Helium jet

    NASA Technical Reports Server (NTRS)

    Panchapakesan, N. R.; Lumley, J. L.

    1993-01-01

    Results are presented of measurements on turbulent round jets of air and of helium of the same nozzle momentum efflux, using, for the air jets, x-wire hot-wire probes mounted on a moving shuttle and, for He jets, a composite probe consisting of an interference probe of the Way-Libby type and an x-probe. Current models for scalar triple moments were evaluated. It was found that the performance of the model termed the Full model, which includes all terms except advection, was very good for both the air and the He jets.

  12. First observations of Gigantic Jets from Monsoon Thunderstorms over India

    NASA Astrophysics Data System (ADS)

    Singh, Rajesh; Maurya, Ajeet; Chanrion, Olivier; Neubert, Torsten; Cummer, Steven; Mlynarczyk, Janusz; Bór, József; Siingh, Devendraa; Cohen, Morris; Kumar, Sushil

    2016-04-01

    Gigantic Jets are electric discharges from thunderstorm cloud tops to the bottom of the ionosphere at ~80 km altitude. After their first discovery in 2001, relatively few observations have been reported. Most of these are from satellites at large distances and a few tens from the ground at higher spatial resolution. Here we report the first Gigantic Jets observed in India from two thunderstorm systems that developed over the land surface from monsoon activity, each storm producing two Gigantic Jets. The jets were recorded by a video camera system at standard video rate (20 ms exposure) at a few hundred km distance. ELF measurements suggest that the jets are of the usual negative polarity and that they develop in less than 40 ms, which is faster than most jets reported in the past. The jets originate from the leading edge of a slowly drifting convective cloud complex close to the highest regions of the clouds and carry ~25 Coulomb of charge to the ionosphere. One jet has a markedly horizontal displacement that we suggest is caused by a combination of close-range cloud electric fields at inception, and longer-range cloud fields at larger distances during full development. The Gigantic Jets are amongst the few that have been observed over land.

  13. Infrared imaging results of an excited planar jet

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Farrington, R.B.

    1991-12-01

    Planar jets are used for many applications including heating, cooling, and ventilation. Generally such a jet is designed to provide good mixing within an enclosure. In building applications, the jet provides both thermal comfort and adequate indoor air quality. Increased mixing rates may lead to lower short-circuiting of conditioned air, elimination of dead zones within the occupied zone, reduced energy costs, increased occupant comfort, and higher indoor air quality. This paper discusses using an infrared imaging system to show the effect of excitation of a jet on the spread angle and on the jet mixing efficiency. Infrared imaging captures amore » large number of data points in real time (over 50,000 data points per image) providing significant advantages over single-point measurements. We used a screen mesh with a time constant of approximately 0.3 seconds as a target for the infrared camera to detect temperature variations in the jet. The infrared images show increased jet spread due to excitation of the jet. Digital data reduction and analysis show change in jet isotherms and quantify the increased mixing caused by excitation. 17 refs., 20 figs.« less

  14. Control of Jet Noise Through Mixing Enhancement

    NASA Technical Reports Server (NTRS)

    Bridges, James; Wernet, Mark; Brown, Cliff

    2003-01-01

    The idea of using mixing enhancement to reduce jet noise is not new. Lobed mixers have been around since shortly after jet noise became a problem. However, these designs were often a post-design fix that rarely was worth its weight and thrust loss from a system perspective. Recent advances in CFD and some inspired concepts involving chevrons have shown how mixing enhancement can be successfully employed in noise reduction by subtle manipulation of the nozzle geometry. At NASA Glenn Research Center, this recent success has provided an opportunity to explore our paradigms of jet noise understanding, prediction, and reduction. Recent advances in turbulence measurement technology for hot jets have also greatly aided our ability to explore the cause and effect relationships of nozzle geometry, plume turbulence, and acoustic far field. By studying the flow and sound fields of jets with various degrees of mixing enhancement and subsequent noise manipulation, we are able to explore our intuition regarding how jets make noise, test our prediction codes, and pursue advanced noise reduction concepts. The paper will cover some of the existing paradigms of jet noise as they relate to mixing enhancement for jet noise reduction, and present experimental and analytical observations that support these paradigms.

  15. Multiplicities of Hadrons Within Jets at STAR

    NASA Astrophysics Data System (ADS)

    Wheeler, Suzanne; Drachenberg, Jim; STAR Collaboration

    2017-09-01

    Jet measurements have long been tools used to understand QCD phenomena. There is still much to be learned from the production of hadrons inside of jets. In particular, hadron yields within jets from proton-proton collisions have been proposed as a way to unearth more information on gluon fragmentation functions. In 2011, the STAR experiment at RHIC collected 23 pb-1 of data from proton-proton collisions at √{ s} = 500 GeV. The jets of most interest for gluon fragmentation functions are those with transverse momentum around 6-15 GeV/c. Large acceptance charged particle tracking and electromagnetic calorimetry make STAR an excellent jet detector. Time-of-flight and specific energy loss in the tracking system allow particle identification on the various types of hadrons within the jets, e.g., distinguishing pions from kaons and protons. An integral part of analyzing the data collected is understanding how the finite resolutions of the various detector subsystems influence the measured jet and hadron kinematics. For this reason, Monte Carlo simulations can be used to track the shifting of the hadron and jet kinematics between the generator level and the detector reconstruction level. The status of this analysis will be presented. We would like to acknowledge the Ronald E. McNair program for supporting this research.

  16. 32 CFR Appendix E to Part 246 - Stars and Stripes (S&S) Board of Directors

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 2 2013-07-01 2013-07-01 false Stars and Stripes (S&S) Board of Directors E... DEFENSE (CONTINUED) MISCELLANEOUS STARS AND STRIPES (S&S) NEWSPAPER AND BUSINESS OPERATIONS Pt. 246, App. E Appendix E to Part 246—Stars and Stripes (S&S) Board of Directors A. Organization and Management...

  17. 32 CFR Appendix E to Part 246 - Stars and Stripes (S&S) Board of Directors

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 2 2014-07-01 2014-07-01 false Stars and Stripes (S&S) Board of Directors E... DEFENSE (CONTINUED) MISCELLANEOUS STARS AND STRIPES (S&S) NEWSPAPER AND BUSINESS OPERATIONS Pt. 246, App. E Appendix E to Part 246—Stars and Stripes (S&S) Board of Directors A. Organization and Management...

  18. 32 CFR Appendix E to Part 246 - Stars and Stripes (S&S) Board of Directors

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 2 2012-07-01 2012-07-01 false Stars and Stripes (S&S) Board of Directors E... DEFENSE (CONTINUED) MISCELLANEOUS STARS AND STRIPES (S&S) NEWSPAPER AND BUSINESS OPERATIONS Pt. 246, App. E Appendix E to Part 246—Stars and Stripes (S&S) Board of Directors A. Organization and Management...

  19. Implementation of QoSS (Quality-of-Security Service) for NoC-Based SoC Protection

    NASA Astrophysics Data System (ADS)

    Sepúlveda, Johanna; Pires, Ricardo; Strum, Marius; Chau, Wang Jiang

    Many of the current electronic systems embedded in a SoC (System-on-Chip) are used to capture, store, manipulate and access critical data, as well as to perform other key functions. In such a scenario, security is considered as an important issue. The Network-on-chip (NoC), as the foreseen communication structure of next-generation SoC devices, can be used to efficiently incorporate security. Our work proposes the implementation of QoSS (Quality of Security Service) to overcome present SoC vulnerabilities. QoSS is a novel concept for data protection that introduces security as a dimension of QoS. In this paper, we present the implementation of two security services (access control and authentication), that may be configured to assume one from several possible levels, the implementation of a technique to avoid denial-of-service (DoS) attacks, evaluate their effectiveness and estimate their impact on NoC performance.

  20. On the Nature of the Compact Object in SS 433: Observational Evidence of X-ray Photon Index Saturation

    NASA Astrophysics Data System (ADS)

    Seifina, Elena; Titarchuk, Lev

    2010-10-01

    We present an analysis of the X-ray spectral properties observed from the black hole candidate (BHC) binary SS 433. We have analyzed Rossi X-ray Timing Explorer data from this source, coordinated with Green Bank Interferometer/RATAN-600. We show that SS 433 undergoes an X-ray spectral transition from the low hard state to the intermediate state (IS). We show that the X-ray broadband energy spectra during all spectral states are well fitted by a sum of the so-called bulk motion Comptonization (BMC) component and by two (broad and narrow) Gaussians for the continuum and line emissions, respectively. In addition to these spectral model components, we also find a strong feature that we identify as a "blackbody-like (BB)" component in which the color temperature is in the range of 4-5 keV in 24 IS spectra during the radio outburst decay in SS 433. Our observational results on the "high-temperature BB" bump lead us to suggest the presence of gravitationally redshifted annihilation line emission in this source. In fact, this spectral feature has been recently reproduced in Monte Carlo simulations by Laurent & Titarchuk. We have also established the photon index saturation at about 2.3 in index versus mass accretion correlation. This index-mass accretion correlation allows us to evaluate the low limit of the black hole (BH) mass of the compact object in SS 433, M_{{bh}}≳ 2 solar masses, using the scaling method using BHC GX 339 - 4 as a reference source. Our estimate of the BH mass in SS 433 is consistent with the recent BH mass measurement using the radial velocity measurements of the binary system by Hillwig & Gies, who find that Mx = (4.3 ± 0.8) solar masses. This is the smallest BH mass found up to now among all BH sources. Moreover, the index saturation effect versus mass accretion rate revealed in SS 433, as in a number of other BH candidates, is strong observational evidence for the presence of a BH in SS 433.

  1. On the Nature of the Compact Object in SS 433. Observational Evidence of X-Ray Photon Index Saturation

    NASA Technical Reports Server (NTRS)

    Seifina, Elena; Titarchuk, Lev

    2010-01-01

    We present an analysis of the X-ray spectral properties observed from black hole , candidate (BHC) binary SS 433. We have analyzed Rossi X-ray Time Explorer (RXTE) data from this source, coordinated with Green Bank Interferometer/RATAN-600. We show that SS 433 undergoes a X-ray spectral transition from the low hard state (LHS) to the intermediate state (IS). We show that the X-ray broad-band energy spectra during all spectral states are well fit by a sum of so called "Bulk Motion Comptonization (BMC) component" and by two (broad and narrow) Gaussians for the continuum and line emissions respectively. In addition to these spectral model components we also find a strong feature that we identify as a" blackbody-like (BB)" component which color temperature is in the range of 4-5 keV in 24 IS spectra during the radio outburst decay in SS 433. Our observational results on the "high temperature BB" bump leads us to suggest the presence of gravitationally redshifted annihilation line emission in this source. In fact this spectral feature has been recently reproduced in Monte Carlo simulations by Laurent and Titarchuk. We have also established the photon index saturation at about 2.3 in index vs mass accretion correlation. This index-mass accretion correlation allows us to evaluate the low limit of black hole (BH) mass of compact object in SS 433, M(sub bh) approximately > 2 solar masses, using the scaling method using BHC GX 339-4 as a reference source. Our estimate of the BH mass in SS 433 is consistent with recent BH mass measurement using the radial-velocity measurements of the binary system by Hillwig & Gies who find that M(sub x)( = (4.3 +/- 0.8) solar masses. This is the smallest BH mass found up to now among all BH sources. Moreover, the index saturation effect versus mass accretion rate revealed in SS 433, like in a number of other BH candidates, is the strong observational evidence for the presence of a BH in SS 433.

  2. Atmospheric-pressure plasma jet system for silicon etching without fluorocarbon gas feed

    NASA Astrophysics Data System (ADS)

    Ohtsu, Yasunori; Nagamatsu, Kenta

    2018-01-01

    We developed an atmospheric-pressure plasma jet (APPJ) system with a tungsten rod electrode coated with C2F4 particles of approximately 0.3 µm diameter for the surface treatment of a silicon wafer. The APPJ was generated by dielectric barrier discharge with a driving frequency of 22 kHz using a He gas flow. The characteristics of the APPJ were examined under various experimental conditions. The plasma jet length increased proportionally to the electric field. It was found that the treatment area of the silicon wafer was approximately 1 mm in diameter. By atomic force microscopy analysis, minute irregularities with a maximum length of about 600 nm and part of a ring-shaped trench were observed. A Si etching rate of approximately 400 nm/min was attained at a low power of 6 W and a He flow rate of 1 L/min without introducing molecular gas including F atoms.

  3. Disinfection of gram-negative and gram-positive bacteria using DynaJets® hydrodynamic cavitating jets.

    PubMed

    Loraine, Gregory; Chahine, Georges; Hsiao, Chao-Tsung; Choi, Jin-Keun; Aley, Patrick

    2012-05-01

    Cavitating jet technologies (DynaJets®) were investigated as a means of disinfection of gram-negative Escherichia coli, Klebsiellapneumoniae, Pseudomonas syringae, and Pseudomonas aeruginosa, and gram-positive Bacillus subtilis. The hydrodynamic cavitating jets were found to be very effective in reducing the concentrations of all of these species. In general, the observed rates of disinfection of gram-negative species were higher than for gram-positive species. However, different gram-negative species also showed significant differences (P. syringae 6-log(10) reduction, P. aeruginosa 2-log(10) reduction) under the same conditions. Disinfection of E. coli repeatedly showed five orders of magnitude reduction in concentration within 45-60-min at low nozzle pressure (2.1 bar). Optimization of nozzle design and operating pressures increased disinfection rates per input energy by several orders of magnitude. The power efficiencies of the hydrodynamic cavitating jets were found to be 10-100 times greater than comparable ultrasonic systems. Copyright © 2011 Elsevier B.V. All rights reserved.

  4. Experimental and theoretical study of combustion jet ignition

    NASA Technical Reports Server (NTRS)

    Chen, D. Y.; Ghoniem, A. F.; Oppenheim, A. K.

    1983-01-01

    A combustion jet ignition system was developed to generate turbulent jets of combustion products containing free radicals and to discharge them as ignition sources into a combustible medium. In order to understand the ignition and the inflammation processes caused by combustion jets, the studies of the fluid mechanical properties of turbulent jets with and without combustion were conducted theoretically and experimentally. Experiments using a specially designed igniter, with a prechamber to build up and control the stagnation pressure upstream of the orifice, were conducted to investigate the formation processes of turbulent jets of combustion products. The penetration speed of combustion jets has been found to be constant initially and then decreases monotonically as turbulent jets of combustion products travel closer to the wall. This initial penetration speed to combustion jets is proportional to the initial stagnation pressure upstream of the orifice for the same stoichiometric mixture. Computer simulations by Chorin's Random Vortex Method implemented with the flame propagation algorithm for the theoretical model of turbulent jets with and without combustion were performed to study the turbulent jet flow field. In the formation processes of the turbulent jets, the large-scale eddy structure of turbulence, the so-called coherent structure, dominates the entrainment and mixing processes. The large-scale eddy structure of turbulent jets in this study is constructed by a series of vortex pairs, which are organized in the form of a staggered array of vortex clouds generating local recirculation flow patterns.

  5. Enceladus Jet Orientations: Effects of Surface Structure

    NASA Astrophysics Data System (ADS)

    Helfenstein, P.; Porco, C.; DiNino, D.

    2013-12-01

    Jetting activity across the South Polar Terrain (SPT) of Enceladus is now known to erupt directly from tiger-stripe rifts and associated fracture systems. However, details of the vent conduit geometry are hidden below the icy surface. The three-dimensional orientations of the erupting jets may provide important clues. Porco et al. (2013, Lunar Planet. Sci. Conf. 44th, p.1775) surveyed jet locations and orientations as imaged at high resolution (< 1.3 km/pixel) by Cassini ISS from 2005 through May 2012. Ninety-eight (98) jets were identified either on the main trunks or branches of the 4 tiger-stripes. The azimuth angles of the jets are seen to vary across the SPT. Here, we use histogram analysis of the survey data to test if the jet azimuths are influenced by their placement relative to surface morphology and tectonic structures. Azimuths are measured positive counterclockwise with zero pointing along the fracture in the direction of the sub-Saturn hemisphere, and rosette histograms were binned in 30° increments. Overall, the jet azimuths are not random and only about 11% of them are co-aligned with the tiger stripe valley. There are preferred diagonal orientations between 105°-165° and again between 255°-345°. These trends are dominant along the Damascus and Baghdad tiger-stripes where more than half of the jets are found. Histograms for Cairo and Alexandria show less-distinct trends, fewer jets being measured there, but combining data from both suggests a different pattern of preferred orientations; from 45°-75° and 265°-280°. Many possible factors could affect the orientations of jets, for example, the conduit shape, the presence of obstacles like narrow medial ridges called 'shark-fins' along tiger-stripe valleys, the possibility that jets may breach the surface at some point other than the center of a tiger-stripe, and the presence of structural fabrics or mechanical weaknesses, such as patterns of cross-cutting fractures. The dominance of diagonally

  6. Immunization with the recombinant antigen Ss-IR induces protective immunity to infection with Strongyloides stercoralis in mice.

    PubMed

    Abraham, David; Hess, Jessica A; Mejia, Rojelio; Nolan, Thomas J; Lok, James B; Lustigman, Sara; Nutman, Thomas B

    2011-10-19

    Human intestinal infections with the nematode Strongyloides stercoralis remain a significant problem worldwide and a vaccine would be a useful addition to the tools available to prevent and control this infection. The goal of this study was to test single antigens for their efficacy in a vaccine against S. stercoralis larvae in mice. Alum was used as the adjuvant in these studies and antigens selected for analysis were either recognized by protective human IgG (Ss-TMY-1, Ss-EAT-6, and Ss-LEC-5) or were known to be highly immunogenic in humans (Ss-NIE-1 and Ss-IR). Only mice immunized with the Ss-IR antigen demonstrated a significant decrease of approximately 80% in the survival of larval parasites in the challenge infection. Antibodies, recovered from mice with protective immunity to S. stercoralis after immunization with Ss-IR, were used to locate the antigen in the larvae. Confocal microscopy revealed that IgG from mice immunized with Ss-IR bound to the surface of the parasites and observations by electron microscopy indicated that IgG bound to granules in the glandular esophagus. Serum collected from mice immunized with Ss-IR passively transferred immunity to naïve mice. These studies demonstrate that Ss-IR, in combination with alum, induces high levels of protective immunity through an antibody dependent mechanism and may therefore be suitable for further development as a vaccine against human strongyloidiasis. Copyright © 2011 Elsevier Ltd. All rights reserved.

  7. Integrated Composite Stiffener Structure (ICoSS) Concept for Planetary Entry Vehicles

    NASA Technical Reports Server (NTRS)

    Kellas, Sotiris

    2016-01-01

    Results from the design, manufacturing, and testing of a lightweight Integrated Composite Stiffened Structure (ICoSS) concept, intended for multi-mission planetary entry vehicles are presented. Tests from both component and full-scale tests for a typical Earth Entry Vehicle forward shell manufactured using the ICoSS concept are presented and advantages of the concept for the particular application of passive Earth Entry Vehicles over other structural concepts are discussed.

  8. Improved Stirling engine performance using jet impingement

    NASA Technical Reports Server (NTRS)

    Johnson, D. C.; Britt, E. J.; Thieme, L. G.

    1982-01-01

    Of the many factors influencing the performance of a Stirling engine, that of transferring the combustion gas heat into the working fluid is crucial. By utilizing the high heat transfer rates obtainable with a jet impingement heat transfer system, it is possible to reduce the flame temperature required for engine operation. Also, the required amount of heater tube surface area may be reduced, resulting in a decrease in the engine nonswept volume and a related increase in engine efficiency. A jet impingement heat transfer system was designed by Rasor Associates, Inc., and tested in the GPU-3 Stirling engine at the NASA Lewis Research Center. For a small penalty in pumping power (less than 0.5% of engine output) the jet impingement heat transfer system provided a higher combustion-gas-side heat transfer coefficient and a smoothing of heater temperature profiles resulting in lower combustion system temperatures and a 5 to 8% increase in engine power output and efficiency.

  9. Brucella Rough Mutant Induce Macrophage Death via Activating IRE1α Pathway of Endoplasmic Reticulum Stress by Enhanced T4SS Secretion

    PubMed Central

    Li, Peng; Tian, Mingxing; Bao, Yanqing; Hu, Hai; Liu, Jiameng; Yin, Yi; Ding, Chan; Wang, Shaohui; Yu, Shengqing

    2017-01-01

    Brucella is a Gram-negative facultative intracellular pathogen that causes the worldwide zoonosis, known as brucellosis. Brucella virulence relies mostly on its ability to invade and replicate within phagocytic cells. The type IV secretion system (T4SS) and lipopolysaccharide are two major Brucella virulence factors. Brucella rough mutants reportedly induce the death of infected macrophages, which is T4SS dependent. However, the underlying molecular mechanism remains unclear. In this study, the T4SS secretion capacities of Brucella rough mutant and its smooth wild-type strain were comparatively investigated, by constructing the firefly luciferase fused T4SS effector, BPE123 and VceC. In addition, quantitative real-time PCR and western blotting were used to analyze the T4SS expression. The results showed that T4SS expression and secretion were enhanced significantly in the Brucella rough mutant. We also found that the activity of the T4SS virB operon promoter was notably increased in the Brucella rough mutant, which depends on quorum sensing-related regulators of VjbR upregulation. Cell infection and cell death assays revealed that deletion of vjbR in the Brucella rough mutant absolutely abolished cytotoxicity within macrophages by downregulating T4SS expression. This suggests that up-regulation of T4SS promoted by VjbR in rough mutant ΔrfbE contribute to macrophage death. In addition, we found that the Brucella rough mutant induce macrophage death via activating IRE1α pathway of endoplasmic reticulum stress. Taken together, our study provide evidence that in comparison to the Brucella smooth wild-type strain, VjbR upregulation in the Brucella rough mutant increases transcription of the virB operon, resulting in overexpression of the T4SS gene, accompanied by the over-secretion of effecter proteins, thereby causing the death of infected macrophages via activating IRE1α pathway of endoplasmic reticulum stress, suggesting novel insights into the molecular

  10. Brucella Rough Mutant Induce Macrophage Death via Activating IRE1α Pathway of Endoplasmic Reticulum Stress by Enhanced T4SS Secretion.

    PubMed

    Li, Peng; Tian, Mingxing; Bao, Yanqing; Hu, Hai; Liu, Jiameng; Yin, Yi; Ding, Chan; Wang, Shaohui; Yu, Shengqing

    2017-01-01

    Brucella is a Gram-negative facultative intracellular pathogen that causes the worldwide zoonosis, known as brucellosis. Brucella virulence relies mostly on its ability to invade and replicate within phagocytic cells. The type IV secretion system (T4SS) and lipopolysaccharide are two major Brucella virulence factors. Brucella rough mutants reportedly induce the death of infected macrophages, which is T4SS dependent. However, the underlying molecular mechanism remains unclear. In this study, the T4SS secretion capacities of Brucella rough mutant and its smooth wild-type strain were comparatively investigated, by constructing the firefly luciferase fused T4SS effector, BPE123 and VceC. In addition, quantitative real-time PCR and western blotting were used to analyze the T4SS expression. The results showed that T4SS expression and secretion were enhanced significantly in the Brucella rough mutant. We also found that the activity of the T4SS virB operon promoter was notably increased in the Brucella rough mutant, which depends on quorum sensing-related regulators of VjbR upregulation. Cell infection and cell death assays revealed that deletion of vjbR in the Brucella rough mutant absolutely abolished cytotoxicity within macrophages by downregulating T4SS expression. This suggests that up-regulation of T4SS promoted by VjbR in rough mutant Δ rfbE contribute to macrophage death. In addition, we found that the Brucella rough mutant induce macrophage death via activating IRE1α pathway of endoplasmic reticulum stress. Taken together, our study provide evidence that in comparison to the Brucella smooth wild-type strain, VjbR upregulation in the Brucella rough mutant increases transcription of the virB operon, resulting in overexpression of the T4SS gene, accompanied by the over-secretion of effecter proteins, thereby causing the death of infected macrophages via activating IRE1α pathway of endoplasmic reticulum stress, suggesting novel insights into the molecular

  11. Rapid Confined Mixing with Transverse Jets Part 1: Single Jet

    NASA Astrophysics Data System (ADS)

    Salazar, David; Forliti, David

    2012-11-01

    Transverse jets have been studied extensively due to their relevance and efficiency in fluid mixing applications. Gas turbine burners, film cooling, and chemical reactors are some examples of rapid transverse jet mixing. Motivated by a lack of universal scaling laws for confined and unconfined transverse jets, a newly developed momentum transfer parameter was found to improve correlation of literature data. Jet column drag and entrainment arguments for momentum transfer are made to derive the parameter. A liquid-phase mixing study was conducted to investigate confined mixing for a low number of jets. Planar laser induced fluorescence was implemented to measure mixture fraction for a single confined transverse jet. Time-averaged cross-sectional images were taken with a light sheet located three diameters downstream of transverse injection. A mixture of water and sodium fluorescein was used to distinguish jet fluid from main flow fluid for the test section images. Image data suggest regimes for under- and overpenetration of jet fluid into the main flow. The scaling parameter is found to correlate optimum unmixedness for multiple diameter ratios at a parameter value of 0.75. Distribution A: Public Release, Public Affairs Clearance Number: 12655.

  12. Ink jet printing of silver metallization for photovoltaics

    NASA Technical Reports Server (NTRS)

    Vest, R. W.

    1985-01-01

    Progress was made in the continuing development of the ink jet printing system for thick film circuits. The unit being used is a prototype ink jet printer. One of the first tasks completed was the complete documentation of this ink jet printing system as it existed. It was determined that this was an essential step in deciding what modifications were needed to the system and how these modifications would be implemented. Design modification studies were started for electronic, mechanical, and programming aspects of the ystem. The areas needeing improvement were discussed and applicable changes decided upon. Some improvments were completed. Although the general areas needing improving were identified and some changes decided upon, the exact details of how other changes can be implemented are yet been decided.

  13. Vortex diode jet

    DOEpatents

    Houck, Edward D.

    1994-01-01

    A fluid transfer system that combines a vortex diode with a jet ejector to transfer liquid from one tank to a second tank by a gas pressurization method having no moving mechanical parts in the fluid system. The vortex diode is a device that has a high resistance to flow in one direction and a low resistance to flow in the other.

  14. End-to-End Information System design at the NASA Jet Propulsion Laboratory

    NASA Technical Reports Server (NTRS)

    Hooke, A. J.

    1978-01-01

    Recognizing a pressing need of the 1980s to optimize the two-way flow of information between a ground-based user and a remote space-based sensor, an end-to-end approach to the design of information systems has been adopted at the Jet Propulsion Laboratory. The objectives of this effort are to ensure that all flight projects adequately cope with information flow problems at an early stage of system design, and that cost-effective, multi-mission capabilities are developed when capital investments are made in supporting elements. The paper reviews the End-to-End Information System (EEIS) activity at the Laboratory, and notes the ties to the NASA End-to-End Data System program.

  15. Understanding jet noise.

    PubMed

    Karabasov, S A

    2010-08-13

    Jets are one of the most fascinating topics in fluid mechanics. For aeronautics, turbulent jet-noise modelling is particularly challenging, not only because of the poor understanding of high Reynolds number turbulence, but also because of the extremely low acoustic efficiency of high-speed jets. Turbulent jet-noise models starting from the classical Lighthill acoustic analogy to state-of-the art models were considered. No attempt was made to present any complete overview of jet-noise theories. Instead, the aim was to emphasize the importance of sound generation and mean-flow propagation effects, as well as their interference, for the understanding and prediction of jet noise.

  16. Endoscope system with plasma flushing and coaxial round jet nozzle for off-pump cardiac surgery.

    PubMed

    Horiuchi, Tetsuya; Masamune, Ken; Iwase, Yuki; Ymashita, Hiromasa; Tsukihara, Hiroyuki; Motomura, Noboru; Ohta, Yuji; Dohi, Takeyoshi

    2011-07-01

    To develop a new endoscope for performing simple surgical tasks inside the blood-filled cardiac atrium/chamber, that is, "off-pump" cardiac surgeries. We developed the endoscope system with plasma flushing and coaxial round jet nozzle. The "plasma flushing" system was invented to observe the interior of the blood-filled heart by displacing blood cells in front of the endoscope tip. However, some areas could not be observed with simple flushing of the liquid because the flushed liquid mixed with blood. Further, a large amount of liquid had to be flushed, which posed a risk of cardiac damage caused by excess volume. Therefore, to safely capture high-resolution images of the interior of the heart, an endoscope with a coaxial round jet nozzle through which plasma is flushed has been developed. And to reduce the volume of flushed liquid, the synchronization system of heartbeat and the endoscope system with plasma flushing has been developed. We conducted an in vivo experiment to determine whether we could observe intracardiac tissues in swine without the use of a heart-lung machine. As a result, we successfully observed intracardiac tissues without using a heart-lung machine. By using a coaxial nozzle, we could even observe the tricuspid valve. Moreover, we were able to save up to 30% of the flushed liquid by replacing the original system with a synchronization system. And we evaluated the performance of the endoscope with the coaxial round jet nozzle by conducting fluid analysis and an in vitro experiment. We successfully observed intracardiac tissues without using a heart-lung machine. By using a coaxial nozzle, we could even observe the tricuspid valve. And by replacing an original system to a synchronization system, we were able to save up to 30% of the flushed liquid. As a follow-up study, we plan to create a surgical flexible device for valve disease that can grasp, staple, and repair cardiac valves by endoscopic visualization.

  17. Acute toxicity evaluation of JP-8 jet fuel and JP-8 jet fuel containing additives. Final report, November 1995-February 1996

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wolfe, R.E.; Kinead, E.R.; Feldmann, M.L.

    1996-11-01

    To reduce fuel fouling in current U.S Navy and Air Force aircraft systems and to provide additional heat sink and thermal stability for future systems, the Air Force is developing an improved JP-8 jet fuel (JP-8 + 100). Two companies (Betz and Mobil) have developed additive packages that are currently being tested in aircraft systems. To determine if the additive packages will produce health effects for flightline personnel, acute testing was performed on JP-8 and the two JP-8 + 100 jet fuels. A single oral dose at 5 mg jet fuel/kg body weight to five male and five female F-344more » rats, and a single dermal application of 2 g jet fuel/kg body weight applied to five male and five female NZW rabbits resulted in no deaths. No signs of toxic stress were observed, and all animals gained weight over the 14-day observation periods. Single treatment of 0.5 mL neat jet fuel to rabbit skin produced negative results for skin irritation. Guinea pigs tailed to elicit a sensitization response following repeated applications of the jet fuels. Inhalation vapor exposure to JP-8, JP-8 + 100 (Betz), and JP-8 (Mobil) were determined to be >3.43, >3.52, and >3.57 mg/L, respectively. LD% values for aerosol exposure to JP-8, JP-8 + 100 (Betz), and JP-8 + 100 (Mobil) were >4.44, >4.39, and >4.54 mg/L, respectively. Under the conditions of these tests, the additive packages did not potentiate the acute effects normally associated with JP-8 jet fuel exposures.« less

  18. Demonstration of a Packaged Capacitive Pressure Sensor System Suitable for Jet Turbofan Engine Health Monitoring

    NASA Technical Reports Server (NTRS)

    Scardelletti, Maximilian C.; Jordan, Jennifer L.; Meredith, Roger D.; Harsh, Kevin; Pilant, Evan; Usrey, Michael W.; Beheim, Glenn M.; Hunter, Gary W.; Zorman, Christian A.

    2016-01-01

    In this paper, the development and characterization of a packaged pressure sensor system suitable for jet engine health monitoring is demonstrated. The sensing system operates from 97 to 117 MHz over a pressure range from 0 to 350 psi and a temperature range from 25 to 500 deg. The sensing system consists of a Clapp-type oscillator that is fabricated on an alumina substrate and is comprised of a Cree SiC MESFET, MIM capacitors, a wire-wound inductor, chip resistors and a SiCN capacitive pressure sensor. The pressure sensor is located in the LC tank circuit of the oscillator so that a change in pressure causes a change in capacitance, thus changing the resonant frequency of the sensing system. The chip resistors, wire-wound inductors and MIM capacitors have all been characterized at temperature and operational frequency, and perform with less than 5% variance in electrical performance. The measured capacitive pressure sensing system agrees very well with simulated results. The packaged pressure sensing system is specifically designed to measure the pressure on a jet turbofan engine. The packaged system can be installed by way of borescope plug adaptor fitted to a borescope port exposed to the gas path of a turbofan engine.

  19. In vivo fate of 125I SS-B (La) injected into mice.

    PubMed Central

    Schrieber, L; Erhardt, C C; Melsom, R D; Venables, P J; McCarthy, D A; Mumford, P A; Horsfall, A C; Maini, R N

    1983-01-01

    The fate of the radiolabelled soluble cellular antigen SS-B (La) was compared with that of other 125I-labelled proteins of known molecular weight (MW) and electrostatic charge, following i.v. injection into BALB/c mice. The plasma half-life of 125I-SS-B was 3 min, while that of 125I-bovine serum albumin (similar MW and electrostatic charge) was 270 min. 125I-heat-aggregated IgG (MW greater than 1 x 10(6)) and 125I-7S human IgG (MW 168,000) had plasma half-lives of 40 min and greater than 300 min, respectively. Liver and kidney showed preferential uptake of 125I-SS-B, followed by a rapid decrease in radioactivity. During this time low MW, trichloroacetic acid (TCA) soluble, material appeared in urine. This suggests a specific uptake mechanism followed by a catabolic phase. These studies demonstrate that normal mice remove 125I-SS-B rapidly from the circulation and then degrade it. This rapid antigen elimination may protect against the induction of potentially harmful autoantibody responses. PMID:6832805

  20. Corrosion studies of DC reactive magnetron sputtered alumina coating on 304 SS

    NASA Astrophysics Data System (ADS)

    Thangaraj, Baskar; Mahadevan, Krishnan

    2017-12-01

    Aluminum oxide films on SS 304 deposited by DC reactive magnetron sputtering technique were studied with respect to the composition of the sputter gas (Ar:O2), gas pressure, substrate temperature, current etc. to achieve good insulating films with high corrosion resistance. The films were characterized by XRD and SEM techniques. Potentiodynamic polarization and electrochemical impedance spectroscopy measurements were made under static conditions in order to evaluate the corrosion performance of the alumina-coated SS 304 for various immersion durations in 0.5 M and 1 M NaCl solution. Alumina-coated SS 304 has low corrosion value of 0.4550 and 1.1090MPY for 24 h immersion time in both solutions. The impedance plots for the alumina coated SS 304 in 1 M NaCl solution at different durations are slightly different to when compared to its immersion in 0.5 M NaCl solutions and are composed of two depressed semi circles. For the alumina coated film, the impedance spectrum decreased, when immersion time increased.

  1. Boosting jet power in black hole spacetimes

    PubMed Central

    Neilsen, David; Lehner, Luis; Palenzuela, Carlos; Hirschmann, Eric W.; Liebling, Steven L.; Motl, Patrick M.; Garrett, Travis

    2011-01-01

    The extraction of rotational energy from a spinning black hole via the Blandford–Znajek mechanism has long been understood as an important component in models to explain energetic jets from compact astrophysical sources. Here we show more generally that the kinetic energy of the black hole, both rotational and translational, can be tapped, thereby producing even more luminous jets powered by the interaction of the black hole with its surrounding plasma. We study the resulting Poynting jet that arises from single boosted black holes and binary black hole systems. In the latter case, we find that increasing the orbital angular momenta of the system and/or the spins of the individual black holes results in an enhanced Poynting flux. PMID:21768341

  2. Improved Phased Array Imaging of a Model Jet

    NASA Technical Reports Server (NTRS)

    Dougherty, Robert P.; Podboy, Gary G.

    2010-01-01

    An advanced phased array system, OptiNav Array 48, and a new deconvolution algorithm, TIDY, have been used to make octave band images of supersonic and subsonic jet noise produced by the NASA Glenn Small Hot Jet Acoustic Rig (SHJAR). The results are much more detailed than previous jet noise images. Shock cell structures and the production of screech in an underexpanded supersonic jet are observed directly. Some trends are similar to observations using spherical and elliptic mirrors that partially informed the two-source model of jet noise, but the radial distribution of high frequency noise near the nozzle appears to differ from expectations of this model. The beamforming approach has been validated by agreement between the integrated image results and the conventional microphone data.

  3. Design of a new abrasive slurry jet generator

    NASA Astrophysics Data System (ADS)

    Wang, F. C.; Shi, L. L.; Guo, C. W.

    2017-12-01

    With the advantages of a low system working pressure, good jet convergence and high cutting quality, abrasive slurry jet (ASJ) has broad application prospects in material cutting and equipment cleaning. Considering that the generator plays a crucial role in ASJ system, the paper designed a new type ASJ generator using an electric oil pump, a separate plunger cylinder, and a spring energized seal. According to the determining of structure shape, size and seal type, a new ASJ generator has been manufactured out and tested by a series of experiments. The new generator separates the abrasive slurry from the dynamic hydraulic oil, which can improve the service life of the ASJ system. And the new ASJ system can reach 40 MPa and has good performance in jet convergence, which deserves to popularization and application in materials machining.

  4. Environmental Assessment: Installation of Thermally Stable Jet Fuel (JPTS) Above Ground Storage System Westover Air Reserve Base, Chicopee, Massachusetts

    DTIC Science & Technology

    2004-06-30

    gasoline fuels is a result ofleaking USTs in the Aqua System Site (SS-19) to the north. Volatile petroleum hydrocarbon ( VPH ) contamination from the...in- situ enhanced bioremediation plan wilJ be implemented to reduce the concentrations of VPH that are present in soils in the groundwater saturated

  5. An Ss Model with Adverse Selection.

    ERIC Educational Resources Information Center

    House, Christopher L.; Leahy, John V.

    2004-01-01

    We present a model of the market for a used durable in which agents face fixed costs of adjustment, the magnitude of which depends on the degree of adverse selection in the secondary market. We find that, unlike typical models, the sS bands in our model contract as the variance of the shock increases. We also analyze a dynamic version of the model…

  6. Control of jet noise

    NASA Technical Reports Server (NTRS)

    Schreck, Stefan

    1993-01-01

    This reports describes experiments conducted at the High-Speed Jet Facility at the University of Southern California on supersonic jets. The goal of the study was to develop methods for controlling the noise emitted from supersonic jets by passive and/or active means. Work by Seiner et al (1991) indicates that eddy Mach wave radiation is the dominant noise source in a heated high speed jet. Eddy Mach radiation is caused by turbulent eddies traveling at supersonic speed in the shear layer of the jet. The convection velocity of the eddies decays with increasing distance from the nozzle exit due to the mixing of the jet stream with the ambient fluid. Once the convection speed reaches subsonic velocities, eddy Mach wave radiation ceases. To control noise, a rapid decay of the convection velocity is desired. This may be accomplished by enhanced mixing in the jet. In this study, small aspect ratio rectangular jet nozzles were tested. A flapping mode was noticed in the jets. By amplifying screech components of the jets and destabilizing the jet columns with a collar device, the flapping mode was excited. The result was a rapid decay of the jet velocity. A reduction in eddy Mach radiation in rectangular supersonic jets may be achieved with this device.

  7. Project ExPreSS: Social studies and science remediation program for the Georgia High School Graduation Test

    NASA Astrophysics Data System (ADS)

    Shearouse, Randy

    Over half of the states now require students to pass a high stakes exit exam before being allowed to graduate from high school. No Child Left Behind requires that standardized testing be included to determine whether or not a school makes Adequate Yearly Progress (AYP). The purpose of this study is to examine the results of the Georgia High School Graduation Test (GHSGT) of students who participated in the remedial program Project ExPreSS with those students who did not participate. Using a quantitative research design, the question that will be answered is whether Project ExPreSS makes a difference in passing the GHSGT in science and social studies among three groups: all Georgia students, African American students in one Georgia school system, and all students in one Georgia school system. A chi-square test was conducted and a determination was made that there is a statistically significant relationship between project participation and pass-fail status in all but one area. The majority of students in this study were 17--18 years of age and were taking the science or social studies section of the GHSGT for the second time. The findings of this study will be important not only for Georgia and the school system examined, but also for other states and systems that give High Stakes Exit Exams (HSEEs). The results indicate that highly focused remedial programs like Project ExPreSS make a difference for students who may not be successful on their first attempt at passing a HSEE.

  8. Differential biotin labelling of the cell envelope proteins in lipopolysaccharidic diderm bacteria: Exploring the proteosurfaceome of Escherichia coli using sulfo-NHS-SS-biotin and sulfo-NHS-PEG4-bismannose-SS-biotin.

    PubMed

    Monteiro, Ricardo; Chafsey, Ingrid; Leroy, Sabine; Chambon, Christophe; Hébraud, Michel; Livrelli, Valérie; Pizza, Mariagrazia; Pezzicoli, Alfredo; Desvaux, Mickaël

    2018-06-15

    Surface proteins are the major factor for the interaction between bacteria and its environment, playing an important role in infection, colonisation, virulence and adaptation. However, the study of surface proteins has proven difficult mainly due to their hydrophobicity and/or relatively low abundance compared with cytoplasmic proteins. To overcome these issues new proteomic strategies have been developed, such as cell-surface protein labelling using biotinylation reagents. Sulfo-NHS-SS-biotin is the most commonly used reagent to investigate the proteins expressed at the cell surface of various organisms but its use in lipopolysaccharidic diderm bacteria (archetypical Gram-negative bacteria) remains limited to a handful of species. While generally pass over in silence, some periplasmic proteins, but also some inner membrane lipoproteins, integral membrane proteins and cytoplasmic proteins (cytoproteins) are systematically identified following this approach. To limit cell lysis and diffusion of the sulfo-NHS-SS-biotin through the outer membrane, biotin labelling was tested over short incubation times and proved to be as efficient for 1 min at room temperature. To further limit labelling of protein located below the outer membrane, the use of high-molecular weight sulfo-NHS-PEG4-bismannose-SS-biotin appeared to recover differentially cell-envelope proteins compared to low-molecular weight sulfo-NHS-SS-biotin. Actually, the sulfo-NHS-SS-biotin recovers at a higher extent the proteins completely or partly exposed in the periplasm than sulfo-NHS-PEG4-bismannose-SS-biotin, namely periplasmic and integral membrane proteins as well as inner membrane and outer membrane lipoproteins. These results highlight that protein labelling using biotinylation reagents of different sizes provides a sophisticated and accurate way to differentially explore the cell envelope proteome of lipopolysaccharidic diderm bacteria. While generally pass over in silence, some periplasmic proteins

  9. Exotic interactions among C-jets and Pb-jets

    NASA Technical Reports Server (NTRS)

    1985-01-01

    The C-jets and Pb-jets were surveyed on the part of Chacaltaya emulsion chamber No.19 amounting to an exposure of 28.8 sq m yr. It is shown that the adopted events make up an unbiased sample of C-jets for sigma sub E gamma TeV. Mini-Centauro interaction gives the most natural explanation for the eight pinaught-less C-jets with three or more constituent shower core. Out of the eight double-cored pinaught-less events, three are found to have visible invariant masses 1.8 GeV/c. Three Pb-jets-lower are composed of double cores whose respective visible transverse momenta are greater than 0.5 GeV/c, suggesting that they are of Geminion origin or chiron origin. The energies of the parent particles are estimated to be 100 to 200 TeV for all three kinds of events. The implications of this energy estimate and the frequency of observed exotic events are discussed.

  10. Forward-facing cavity and opposing jet combined thermal protection system

    NASA Astrophysics Data System (ADS)

    Lu, H. B.; Liu, W. Q.

    2012-12-01

    This paper focuses on the design of a forward-facing cavity and opposing jet combined configuration for thermal protection system (TPS) of hypersonic vehicles. The cooling efficiency of the combined TPS was investigated numerically, and the numerical method was validated by the related experiment in the open literature. The flow field parameters, aerodynamic force, and surface heat flux distribution were obtained. The detailed numerical results show that this kind of combined TPS has an excellent impact on cooling the nose-tip, and it is suitable for the thermal protection of hypersonic vehicles which require long-range and time to cruise.

  11. Blowout Jets: Hinode X-Ray Jets that Don't Fit the Standard Model

    NASA Technical Reports Server (NTRS)

    Moore, Ronald L.; Cirtain, Jonathan W.; Sterling, Alphonse C.; Falconer, David A.

    2010-01-01

    Nearly half of all H-alpha macrospicules in polar coronal holes appear to be miniature filament eruptions. This suggests that there is a large class of X-ray jets in which the jet-base magnetic arcade undergoes a blowout eruption as in a CME, instead of remaining static as in most solar X-ray jets, the standard jets that fit the model advocated by Shibata. Along with a cartoon depicting the standard model, we present a cartoon depicting the signatures expected of blowout jets in coronal X-ray images. From Hinode/XRT movies and STEREO/EUVI snapshots in polar coronal holes, we present examples of (1) X-ray jets that fit the standard model, and (2) X-ray jets that do not fit the standard model but do have features appropriate for blowout jets. These features are (1) a flare arcade inside the jet-base arcade in addition to the small flare arcade (bright point) outside that standard jets have, (2) a filament of cool (T is approximately 80,000K) plasma that erupts from the core of the jetbase arcade, and (3) an extra jet strand that should not be made by the reconnection for standard jets but could be made by reconnection between the ambient unipolar open field and the opposite-polarity leg of the filament-carrying flux-rope core field of the erupting jet-base arcade. We therefore infer that these non-standard jets are blowout jets, jets made by miniature versions of the sheared-core-arcade eruptions that make CMEs

  12. Velocity field near the jet orifice of a round jet in a crossflow

    NASA Technical Reports Server (NTRS)

    Fearn, R. L.; Benson, J. P.

    1979-01-01

    Experimentally determined velocities at selected locations near the jet orifice are presented and analyzed for a round jet in crossflow. Jet-to-crossflow velocity ratios of four and eight were studied experimentally for a round subsonic jet of air exhausting perpendicularly through a flat plate into a subsonic crosswind of the same temperature. Velocity measurements were made in cross sections to the jet plume located from one to four jet diameters from the orifice. Jet centerline and vortex properties are presented and utilized to extend the results of a previous study into the region close to the jet orifice.

  13. Rosetta Comet Spreads its Jets

    NASA Image and Video Library

    2014-10-24

    This image was taken by the Optical, Spectroscopic, and Infrared Remote Imaging System, Rosetta main onboard scientific imaging system, on Sept. 10, 2014. Jets of cometary activity can be seen along almost the entire body of the comet.

  14. Trapezium Systems and Stellar Jets in 30 Doradus

    NASA Astrophysics Data System (ADS)

    Walborn, Nolan

    1999-07-01

    30 Doradus is the nearest and best resolved extragalactic starburst, hence a paradigm for the phenomenon. Recent NICMOS observations of the new stellar generation being triggered by the outflows from R136 establish 30 Dor as a prime region for investigation of massive-star formation as well. Since 1" already subtends 50, 000 AU at 50 kpc, HST makes unique contributions to the study of 30 Dor. A recent groundbased spectral-classification study has provided new insights into the stellar content of 30 Dor, but many of the targets are resolved into multiple systems in the available WFPC2 images. We propose to obtain spatially resolved STIS blue spectroscopy of some of the newly found multiple systems, which is essential to determine accurate stellar tempertures and masses. Several systems each in the new and previous stellar generations are included. The HST spatial resolution also reduces the contamination of t he stellar spectra by the nebula r emission lines, which is a critical advantage. We also propose dithered PC nebular-line images of the young Trapezium systems Knots 1-3, which interact strongly with the surrounding interstellar medium, forming several parsec-scale jets. Finally, we shall do two WFPC2 pointings with continuum filters, to complete the coverage of the field, which currently limits the search for multiple systems and the illuminating comparisons with IR and other data.

  15. Excessive Counterion Condensation on Immobilized ssDNA in Solutions of High Ionic Strength

    PubMed Central

    Rant, Ulrich; Arinaga, Kenji; Fujiwara, Tsuyoshi; Fujita, Shozo; Tornow, Marc; Yokoyama, Naoki; Abstreiter, Gerhard

    2003-01-01

    We present experiments on the bias-induced release of immobilized, single-stranded (ss) 24-mer oligonucleotides from Au-surfaces into electrolyte solutions of varying ionic strength. Desorption is evidenced by fluorescence measurements of dye-labeled ssDNA. Electrostatic interactions between adsorbed ssDNA and the Au-surface are investigated with respect to 1), a variation of the bias potential applied to the Au-electrode; and 2), the screening effect of the electrolyte solution. For the latter, the concentration of monovalent salt in solution is varied from 3 to 1600 mM. We find that the strength of electric interaction is predominantly determined by the effective charge of the ssDNA itself and that the release of DNA mainly occurs before the electrochemical double layer has been established at the electrolyte/Au interface. In agreement with Manning's condensation theory, the measured desorption efficiency (ηrel) stays constant over a wide range of salt concentrations; however, as the Debye length is reduced below a value comparable to the axial charge spacing of the DNA, ηrel decreases substantially. We assign this effect to excessive counterion condensation on the DNA in solutions of high ionic strength. In addition, the relative translational diffusion coefficient of ssDNA in solution is evaluated for different salt concentrations. PMID:14645075

  16. Excessive counterion condensation on immobilized ssDNA in solutions of high ionic strength.

    PubMed

    Rant, Ulrich; Arinaga, Kenji; Fujiwara, Tsuyoshi; Fujita, Shozo; Tornow, Marc; Yokoyama, Naoki; Abstreiter, Gerhard

    2003-12-01

    We present experiments on the bias-induced release of immobilized, single-stranded (ss) 24-mer oligonucleotides from Au-surfaces into electrolyte solutions of varying ionic strength. Desorption is evidenced by fluorescence measurements of dye-labeled ssDNA. Electrostatic interactions between adsorbed ssDNA and the Au-surface are investigated with respect to 1), a variation of the bias potential applied to the Au-electrode; and 2), the screening effect of the electrolyte solution. For the latter, the concentration of monovalent salt in solution is varied from 3 to 1600 mM. We find that the strength of electric interaction is predominantly determined by the effective charge of the ssDNA itself and that the release of DNA mainly occurs before the electrochemical double layer has been established at the electrolyte/Au interface. In agreement with Manning's condensation theory, the measured desorption efficiency (etarel) stays constant over a wide range of salt concentrations; however, as the Debye length is reduced below a value comparable to the axial charge spacing of the DNA, etarel decreases substantially. We assign this effect to excessive counterion condensation on the DNA in solutions of high ionic strength. In addition, the relative translational diffusion coefficient of ssDNA in solution is evaluated for different salt concentrations.

  17. Transverse jet shear layer instabilities and their control

    NASA Astrophysics Data System (ADS)

    Karagozian, Ann

    2013-11-01

    The jet in crossflow, or transverse jet, is a canonical flowfield that has relevance to engineering systems ranging from dilution jets and film cooling for gas turbine engines to thrust vector control and fuel injection in high speed aerospace vehicles to environmental control of effluent from chimney and smokestack plumes. Over the years, our UCLA Energy and Propulsion Research Lab's studies on this flowfield have focused on the dynamics of the vorticity associated with equidensity and variable density jets in crossflow, including the stability characteristics of the jet's upstream shear layer. A range of different experimental diagnostics have been used to study the jet's upstream shear layer, whereby a transition from convectively unstable behavior at high jet-to-crossflow momentum flux ratios to absolutely unstable flow at low momentum flux and/or density ratios is identified. These differences in shear layer stability characteristics have a profound effect on how one employs external excitation to control jet penetration, spread, and mixing, depending on the flow regime and specific engineering application. These control strategies, and challenges for future research directions, will be identified in this presentation.

  18. Inclusive production of small radius jets in heavy-ion collisions

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kang, Zhong-Bo; Ringer, Felix; Vitev, Ivan

    Here, we develop a new formalism to describe the inclusive production of small radius jets in heavy-ion collisions, which is consistent with jet calculations in the simpler proton–proton system. Only at next-to-leading order (NLO) and beyond, the jet radius parameter R and the jet algorithm dependence of the jet cross section can be studied and a meaningful comparison to experimental measurements is possible. We are able to consistently achieve NLO accuracy by making use of the recently developed semi-inclusive jet functions within Soft Collinear Effective Theory (SCET). Additionally, single logarithms of the jet size parameter αmore » $$n\\atop{s}$$ln nR leading logarithmic (NLL R) accuracy in proton–proton collisions. The medium modified semi-inclusive jet functions are obtained within the framework of SCET with Glauber gluons that describe the interaction of jets with the medium. We also present numerical results for the suppression of inclusive jet cross sections in heavy ion collisions at the LHC and the formalism developed here can be extended directly to corresponding jet substructure observables.« less

  19. Inclusive production of small radius jets in heavy-ion collisions

    DOE PAGES

    Kang, Zhong-Bo; Ringer, Felix; Vitev, Ivan

    2017-03-31

    Here, we develop a new formalism to describe the inclusive production of small radius jets in heavy-ion collisions, which is consistent with jet calculations in the simpler proton–proton system. Only at next-to-leading order (NLO) and beyond, the jet radius parameter R and the jet algorithm dependence of the jet cross section can be studied and a meaningful comparison to experimental measurements is possible. We are able to consistently achieve NLO accuracy by making use of the recently developed semi-inclusive jet functions within Soft Collinear Effective Theory (SCET). Additionally, single logarithms of the jet size parameter αmore » $$n\\atop{s}$$ln nR leading logarithmic (NLL R) accuracy in proton–proton collisions. The medium modified semi-inclusive jet functions are obtained within the framework of SCET with Glauber gluons that describe the interaction of jets with the medium. We also present numerical results for the suppression of inclusive jet cross sections in heavy ion collisions at the LHC and the formalism developed here can be extended directly to corresponding jet substructure observables.« less

  20. Formation of Bipolar Lobes by Jets

    NASA Astrophysics Data System (ADS)

    Soker, Noam

    2002-04-01

    I conduct an analytical study of the interaction of jets, or a collimated fast wind (CFW), with a previously blown asymptotic giant branch (AGB) slow wind. Such jets (or CFWs) are supposedly formed when a compact companion, a main-sequence star, or a white dwarf accretes mass from the AGB star, forms an accretion disk, and blows two jets. This type of flow, which I think shapes bipolar planetary nebulae (PNs), requires three-dimensional gasdynamical simulations, which are limited in the parameter space they can cover. By imposing several simplifying assumptions, I derive simple expressions which reproduce some basic properties of lobes in bipolar PNs and which can be used to guide future numerical simulations. I quantitatively apply the results to two proto-PNs. I show that the jet interaction with the slow wind can form lobes which are narrow close to, and far away from, the central binary system, and which are wider somewhere in between. Jets that are recollimated and have constant cross section can form cylindrical lobes with constant diameter, as observed in several bipolar PNs. Close to their source, jets blown by main-sequence companions are radiative; only further out they become adiabatic, i.e., they form high-temperature, low-density bubbles that inflate the lobes.

  1. Toxicity of Neurons Treated with Herbicides and Neuroprotection by Mitochondria-Targeted Antioxidant SS31

    PubMed Central

    Reddy, Tejaswini P.; Manczak, Maria; Calkins, Marcus J.; Mao, Peizhong; Reddy, Arubala P.; Shirendeb, Ulziibat; Park, Byung; Reddy, P. Hemachandra

    2011-01-01

    The purpose of this study was to determine the neurotoxicity of two commonly used herbicides: picloram and triclopyr and the neuroprotective effects of the mitochondria-targeted antioxidant, SS31. Using mouse neuroblastoma (N2a) cells and primary neurons from C57BL/6 mice, we investigated the toxicity of these herbicides, and protective effects of SS1 peptide against picloram and triclopyr toxicity. We measured total RNA content, cell viability and mRNA expression of peroxiredoxins, neuroprotective genes, mitochondrial-encoded electron transport chain (ETC) genes in N2a cells treated with herbicides and SS31. Using primary neurons from C57BL/6 mice, neuronal survival was studied in neurons treated with herbicides, in neurons pretreated with SS31 plus treated with herbicides, neurons treated with SS31 alone, and untreated neurons. Significantly decreased total RNA content, and cell viability in N2a cells treated with picloram and triclopyr were found compared to untreated N2a cells. Decreased mRNA expression of neuroprotective genes, and ETC genes in cells treated with herbicides was found compared to untreated cells. Decreased mRNA expression of peroxiredoxins 1–6 in N2a cells treated with picloram was found, suggesting that picloram affects the antioxidant enzymes in N2a cells. Immunofluorescence analysis of primary neurons revealed that decreased neuronal branching and degenerating neurons in neurons treated with picloram and triclopyr. However, neurons pretreated with SS31 prevented degenerative process caused by herbicides. Based on these results, we propose that herbicides—picloram and triclopyr appear to damage neurons, and the SS31 peptide appears to protect neurons from herbicide toxicity. PMID:21318024

  2. Three-Dimensional Modeling of Quasi-Homologous Solar Jets

    NASA Technical Reports Server (NTRS)

    Pariat, E.; Antiochos, S. K.; DeVore, C. R.

    2010-01-01

    Recent solar observations (e.g., obtained with Hinode and STEREO) have revealed that coronal jets are a more frequent phenomenon than previously believed. This higher frequency results, in part, from the fact that jets exhibit a homologous behavior: successive jets recur at the same location with similar morphological features. We present the results of three-dimensional (31)) numerical simulations of our model for coronal jets. This study demonstrates the ability of the model to generate recurrent 3D untwisting quasi-homologous jets when a stress is constantly applied at the photospheric boundary. The homology results from the property of the 3D null-point system to relax to a state topologically similar to its initial configuration. In addition, we find two distinct regimes of reconnection in the simulations: an impulsive 3D mode involving a helical rotating current sheet that generates the jet, and a quasi-steady mode that occurs in a 2D-like current sheet located along the fan between the sheared spines. We argue that these different regimes can explain the observed link between jets and plumes.

  3. Development of a temperature measurement system with application to a jet in a cross flow experiment

    NASA Technical Reports Server (NTRS)

    Wark, C.; Foss, J. F.

    1985-01-01

    A temperature measurement system, which allows the simultaneous sampling of up to 80 separate thermocouples, was developed. The minimum resolution for the system corresponds to + or - 0.16 C per least significant bit of the A/D converter. The time constant values lambda, for each of the 64 thermocouples, were determined experimentally at 7 mps. Software routines were used to correct the measured temperatures for the effect of lambda for each thermocouple. The temperature measurement system was utilized to study the thermal field of a heated jet discharging perpendicularly into a low and a high disturbance level cross stream for a given momentum flux ratio and for three overheated values. The peak instantaneous temperatures reveal that strong molecular diffusion was operative. Various measures of the thermal field, for the disturbed case, suggest that the jet column remains relatively compact while being buffeted by the ambient turbulence field and that its penetration, into the cross wind, is inhibited by the presence of the strong disturbance field.

  4. Dynamic interaction of a downward plane jet and a cough jet with respect to particle transmission: An analytical and experimental study.

    PubMed

    Cao, Guangyu; Liu, Shichao; Boor, Brandon E; Novoselac, Atila

    2017-08-01

    A cough jet can travel beyond the breathing zone of the source person, and thus, infectious viral- and bacterial-laden particles can be transported from the source person to others in close proximity. To reduce the interpersonal transmission of coughed particles, the objective of this study was to analytically and experimentally investigate the performance of downward plane jets with various discharge velocities. Chamber measurements were conducted to examine the interaction between a transient cough jet (discharge velocities of 12 m/sec and 16 m/sec) and a steady downward plane jet (discharge velocities from 1.0-8.5 m/sec) with respect to the transport of and human exposure to coughed particles. The results show that a relatively high-speed cough can easily penetrate a downward plane jet with a discharge velocity of less than 6 m/sec. A downward plane jet with a discharge velocity of 8.5 m/sec can bend the cough jet to a certain extent. In this study, momentum comparison of the cough jet and the downward plane jet shows that the value of personal exposure to coughed particles depends on the ratio of jet momentums. The results show that when the two momentums are equivalent or if the downward plane jet has a greater momentum, the cough jet is deflected downward and does not reach the breathing zone of the target thermal dummy. Using the ratio of the two momentums, it may be estimated whether the transmission of a cough jet can be controlled. A trajectory model was developed based on the ratio of the two momentums of a cough jet and a downward jet and was validated using the experimental data. In addition, the predicted trajectory of the cough jet agreed well with the results from smoke visualization experiments. This model can be used to guide the design of downward plane jet systems for protection of occupants from coughed particles.

  5. A performance application study of a jet-flap helicopter rotor

    NASA Technical Reports Server (NTRS)

    Sullivan, R. J.; Laforge, S.; Holchin, B. W.

    1972-01-01

    A performance study was made of the application of a jet-flap to a reaction-drive rotor for a heavy-lift helicopter mission and for a high-speed-helicopter maneuverability (200 knots, 2g) mission. The results of the study are as follows: As a result of the increase in maximum airfoil lift coefficient achieved by the jet-flap, rotor solidity is reduced with the jet-flap to approximately 59% of a nonjet-flap rotor. As a result of the saving in rotor solidity, and hence in rotor weight, the jet-flap configuration had a 21% higher productivity than a nonjet-flap configuration. Of the three propulsion systems studied utilizing a jet-flap (hot cycle, warm cycle, cold cycle) the hot cycle gave the largest increase in productivity. The 200 knot 2g mission is performed best with a warm cycle propulsion system. The jet-flap permits designing for a rotor blade loading coefficient C sub T/sigma = .170 at 2g without encountering blade stall. The jet-flap rotor permits a 200 knot 2g maneuver without suffering the penalty of an unreasonable rotor solidity that would be required by a nonjet-flap rotor.

  6. A novel protein elicitor (SsCut) from Sclerotinia sclerotiorum induces multiple defense responses in plants.

    PubMed

    Zhang, Huajian; Wu, Qun; Cao, Shun; Zhao, Tongyao; Chen, Ling; Zhuang, Peitong; Zhou, Xiuhong; Gao, Zhimou

    2014-11-01

    In this study, we report the cloning of the SsCut gene encoding cutinase from Sclerotinia sclerotiorum. We isolated a 609-bp cDNA encoding a polypeptide of 202 amino acids with a molecular weight of 20.4 kDa. Heterologous expression of SsCut in Escherichia coli (His-SsCut) caused the formation of lesions in tobacco that closely resembled hypersensitive response lesions. Mutational analysis identified the C-terminal-half peptide and the same amino acids indispensable for both enzyme and elicitor activity. His-SsCut was caused cell death in Arabidopsis, soybean (Glycine max), oilseed rape (Brassica napus), rice (Oryza sativa), maize (Zea mays), and wheat (Triticum aestivum), indicating that both dicot and monocot species are responsive to the elicitor. Furthermore, the elicitation of tobacco was effective in the induction of the activities of hydrogen peroxide, phenylalanine ammonia-lyase, peroxides, and polyphenol oxidase. His-SsCut-treated plants exhibited enhanced resistance as indicated by a significant reduction in the number and size of S. sclerotiorum, Phytophthora sojae, and P. nicotianae lesions on leaves relative to controls. Real-time PCR results indicated that the expression of defense-related genes and genes involved in signal transduction were induced by His-SsCut. Our results demonstrate that SsCut is an elicitor that triggers defense responses in plants and will help to clarify its relationship to downstream signaling pathways that induce defense responses.

  7. System and method for crystalline sheet growth using a cold block and gas jet

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kellerman, Peter L.; Mackintosh, Brian; Carlson, Frederick M.

    A crystallizer for growing a crystalline sheet from a melt may include a cold block having a cold block surface that faces an exposed surface of the melt, the cold block configured to generate a cold block temperature at the cold block surface that is lower than a melt temperature of the melt at the exposed surface. The system may also include a nozzle disposed within the cold block and configured to deliver a gas jet to the exposed surface, wherein the gas jet and the cold block are interoperative to generate a process zone that removes heat from themore » exposed surface at a first heat removal rate that is greater than a second heat removal rate from the exposed surface in outer regions outside of the process zone.« less

  8. Validity of Automated Choroidal Segmentation in SS-OCT and SD-OCT.

    PubMed

    Zhang, Li; Buitendijk, Gabriëlle H S; Lee, Kyungmoo; Sonka, Milan; Springelkamp, Henriët; Hofman, Albert; Vingerling, Johannes R; Mullins, Robert F; Klaver, Caroline C W; Abràmoff, Michael D

    2015-05-01

    To evaluate the validity of a novel fully automated three-dimensional (3D) method capable of segmenting the choroid from two different optical coherence tomography scanners: swept-source OCT (SS-OCT) and spectral-domain OCT (SD-OCT). One hundred eight subjects were imaged using SS-OCT and SD-OCT. A 3D method was used to segment the choroid and quantify the choroidal thickness along each A-scan. The segmented choroidal posterior boundary was evaluated by comparing to manual segmentation. Differences were assessed to test the agreement between segmentation results of the same subject. Choroidal thickness was defined as the Euclidian distance between Bruch's membrane and the choroidal posterior boundary, and reproducibility was analyzed using automatically and manually determined choroidal thicknesses. For SS-OCT, the average choroidal thickness of the entire 6- by 6-mm2 macular region was 219.5 μm (95% confidence interval [CI], 204.9-234.2 μm), and for SD-OCT it was 209.5 μm (95% CI, 197.9-221.0 μm). The agreement between automated and manual segmentations was high: Average relative difference was less than 5 μm, and average absolute difference was less than 15 μm. Reproducibility of choroidal thickness between repeated SS-OCT scans was high (coefficient of variation [CV] of 3.3%, intraclass correlation coefficient [ICC] of 0.98), and differences between SS-OCT and SD-OCT results were small (CV of 11.0%, ICC of 0.73). We have developed a fully automated 3D method for segmenting the choroid and quantifying choroidal thickness along each A-scan. The method yielded high validity. Our method can be used reliably to study local choroidal changes and may improve the diagnosis and management of patients with ocular diseases in which the choroid is affected.

  9. Coherence resonance in low-density jets

    NASA Astrophysics Data System (ADS)

    Zhu, Yuanhang; Gupta, Vikrant; Li, Larry K. B.

    2017-11-01

    Coherence resonance is a phenomenon in which the response of a stable nonlinear system to noise exhibits a peak in coherence at an intermediate noise amplitude. We report the first experimental evidence of coherence resonance in a purely hydrodynamic system, a low-density jet whose variants can be found in many natural and engineering systems. This evidence comprises four parts: (i) the jet's response amplitude increases as the Reynolds number approaches the instability boundary under a constant noise amplitude; (ii) as the noise amplitude increases, the amplitude distribution of the jet response first becomes unimodal, then bimodal, and finally unimodal again; (iii) a distinct peak emerges in the coherence factor at an intermediate noise amplitude; and (iv) for a subcritical Hopf bifurcation, the decay rate of the autocorrelation function exhibits a maximum at an intermediate noise amplitude, but for a supercritical Hopf bifurcation, the decay rate decreases monotonically with increasing noise amplitude. It is clear that coherence resonance can provide valuable information about a system's nonlinearity even in the unconditionally stable regime, opening up new possibilities for its use in system identification and flow control. This work was supported by the Research Grants Council of Hong Kong (Project No. 16235716 and 26202815).

  10. The free jet as a simulator of forward velocity effects on jet noise

    NASA Technical Reports Server (NTRS)

    Ahuja, K. K.; Tester, B. J.; Tanna, H. K.

    1978-01-01

    A thorough theoretical and experimental study of the effects of the free-jet shear layer on the transmission of sound from a model jet placed within the free jet to the far-field receiver located outside the free-jet flow was conducted. The validity and accuracy of the free-jet flight simulation technique for forward velocity effects on jet noise was evaluated. Transformation charts and a systematic computational procedure for converting measurements from a free-jet simulation to the corresponding results from a wind-tunnel simulation, and, finally, to the flight case were provided. The effects of simulated forward flight on jet mixing noise, internal noise and shock-associated noise from model-scale unheated and heated jets were established experimentally in a free-jet facility. It was illustrated that the existing anomalies between full-scale flight data and model-scale flight simulation data projected to the flight case, could well be due to the contamination of flight data by engine internal noise.

  11. Buoyancy Effects in Turbulent Jet Flames in Crossflow

    NASA Astrophysics Data System (ADS)

    Boxx, Isaac; Idicheria, Cherian; Clemens, Noel

    2003-11-01

    The aim of this study is to investigate the effects of buoyancy on the structure of turbulent, non-premixed hydrocarbon jet-flames in crossflow (JFICF). This was accomplished using a small jet-in-crossflow facility which can be oriented at a variety of angles with respect to the gravity vector. This facility enables us to alter the relative influence of buoyancy on the JFICF without altering the jet-exit Reynolds number, momentum flux ratio or the geometry of the system. Results are compared to similar, but non-buoyant, JFICF studied in microgravity. Departures of jet-centerline trajectory from the well-known power-law scaling of turbulent JFICF were used to explore the transition from a buoyancy-influenced regime to a momentum dominated one. The primary diagnostic was CCD imaging of soot-luminosity. We present results on ethylene jet flames with jet-exit Reynolds numbers of 1770 to 8000 and momentum flux ratios of 5 to 13.

  12. Supersonic cruise vehicle research/business jet

    NASA Technical Reports Server (NTRS)

    Kelly, R. J.

    1980-01-01

    A comparison study of a GE-21 variable propulsion system with a Multimode Integrated Propulsion System (MMIPS) was conducted while installed in small M = 2.7 supersonic cruise vehicles with military and business jet possibilities. The 1984 state of the art vehicles were sized to the same transatlantic range, takeoff distance, and sideline noise. The results indicate the MMIPS would result in a heavier vehicle with better subsonic cruise performance. The MMIPS arrangement with one fan engine and two satellite turbojet engines would not be appropriate for a small supersonic business jet because of design integration penalties and lack of redundancy.

  13. Safe and effective error rate monitors for SS7 signaling links

    NASA Astrophysics Data System (ADS)

    Schmidt, Douglas C.

    1994-04-01

    This paper describes SS7 error monitor characteristics, discusses the existing SUERM (Signal Unit Error Rate Monitor), and develops the recently proposed EIM (Error Interval Monitor) for higher speed SS7 links. A SS7 error monitor is considered safe if it ensures acceptable link quality and is considered effective if it is tolerant to short-term phenomena. Formal criteria for safe and effective error monitors are formulated in this paper. This paper develops models of changeover transients, the unstable component of queue length resulting from errors. These models are in the form of recursive digital filters. Time is divided into sequential intervals. The filter's input is the number of errors which have occurred in each interval. The output is the corresponding change in transmit queue length. Engineered EIM's are constructed by comparing an estimated changeover transient with a threshold T using a transient model modified to enforce SS7 standards. When this estimate exceeds T, a changeover will be initiated and the link will be removed from service. EIM's can be differentiated from SUERM by the fact that EIM's monitor errors over an interval while SUERM's count errored messages. EIM's offer several advantages over SUERM's, including the fact that they are safe and effective, impose uniform standards in link quality, are easily implemented, and make minimal use of real-time resources.

  14. Exhaust-gas measurements from NASAs HYMETS arc jet.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Miller, Paul Albert

    Arc-jet wind tunnels produce conditions simulating high-altitude hypersonic flight such as occurs upon entry of space craft into planetary atmospheres. They have traditionally been used to study flight in Earth's atmosphere, which consists mostly of nitrogen and oxygen. NASA is presently using arc jets to study entry into Mars' atmosphere, which consists of carbon dioxide and nitrogen. In both cases, a wide variety of chemical reactions take place among the gas constituents and with test articles placed in the flow. In support of those studies, we made measurements using a residual gas analyzer (RGA) that sampled the exhaust stream ofmore » a NASA arc jet. The experiments were conducted at the HYMETS arc jet (Hypersonic Materials Environmental Test System) located at the NASA Langley Research Center, Hampton, VA. This report describes our RGA measurements, which are intended to be used for model validation in combination with similar measurements on other systems.« less

  15. Binding of antibodies to the extractable nuclear antigens SS-A/Ro and SS-B/La is induced on the surface of human keratinocytes by ultraviolet light (UVL): Implications for the pathogenesis of photosensitive cutaneous lupus

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Furukawa, F.; Kashihara-Sawami, M.; Lyons, M.B.

    1990-01-01

    Autoantibodies to the non-histone nucleoprotein antigens SS-A/Ro, SS-B/La, and RNP are highly associated with photosensitive cutaneous lupus erythematosus (LE). In order to better understand the potential mechanisms of ultraviolet (UV) light on photosensitivity in patients with cutaneous LE, we designed immunopathologic in vitro and in vivo experiments to evaluate the effects of UV on the binding of such autoantibodies to the surface of human keratinocytes, one major target of immunologic damage in photosensitive LE. Short-term 2% paraformaldehyde fixation of suspensions of cultured human keratinocytes previously incubated with monospecific antiserum probes enabled the detection of ENA expression on the cell surfacemore » by flow-cytometry analysis. UVB light (280-320 nm) induced the binding of monospecific antibody probes for SS-A/Ro and SS-B/La on keratinocytes in a dose-dependent pattern with maximal induction observed at the dose of 200 mJ/cm2 UVB. Binding of SS-A/Ro, SS-B/La, and RNP antibody was augmented strongly, but binding of anti-Sm was very weak. In contrast, UVA (320-400 nm) light had no effect on the induction of binding of these antibody probes. Identical results were seen by standard immunofluorescence techniques. Hydroxyurea-treated keratinocytes showed similar induction of those antigens by UVB irradiation, which suggested that ENA expression on cultured keratinocytes by UVB were cell-cycle independent. Tunicamycin, an inhibitor of glycosylation of proteins, reduced UVB light effect on the SS-A/Ro and SS-B/La antigen's expression. These in vitro FACS analyses revealed that ENA augmentation on the keratinocyte cell surface was dose dependent, UVB dependent, glycosylation dependent, and cell-cycle independent. In vivo ENA augmentation on the keratinocyte surface was examined in suction blister epidermal roofs.« less

  16. A Physics-driven Neural Networks-based Simulation System (PhyNNeSS) for multimodal interactive virtual environments involving nonlinear deformable objects

    PubMed Central

    De, Suvranu; Deo, Dhannanjay; Sankaranarayanan, Ganesh; Arikatla, Venkata S.

    2012-01-01

    Background While an update rate of 30 Hz is considered adequate for real time graphics, a much higher update rate of about 1 kHz is necessary for haptics. Physics-based modeling of deformable objects, especially when large nonlinear deformations and complex nonlinear material properties are involved, at these very high rates is one of the most challenging tasks in the development of real time simulation systems. While some specialized solutions exist, there is no general solution for arbitrary nonlinearities. Methods In this work we present PhyNNeSS - a Physics-driven Neural Networks-based Simulation System - to address this long-standing technical challenge. The first step is an off-line pre-computation step in which a database is generated by applying carefully prescribed displacements to each node of the finite element models of the deformable objects. In the next step, the data is condensed into a set of coefficients describing neurons of a Radial Basis Function network (RBFN). During real-time computation, these neural networks are used to reconstruct the deformation fields as well as the interaction forces. Results We present realistic simulation examples from interactive surgical simulation with real time force feedback. As an example, we have developed a deformable human stomach model and a Penrose-drain model used in the Fundamentals of Laparoscopic Surgery (FLS) training tool box. Conclusions A unique computational modeling system has been developed that is capable of simulating the response of nonlinear deformable objects in real time. The method distinguishes itself from previous efforts in that a systematic physics-based pre-computational step allows training of neural networks which may be used in real time simulations. We show, through careful error analysis, that the scheme is scalable, with the accuracy being controlled by the number of neurons used in the simulation. PhyNNeSS has been integrated into SoFMIS (Software Framework for Multimodal

  17. Characterization of 316L(N)-IG SS joint produced by hot isostatic pressing technique

    NASA Astrophysics Data System (ADS)

    Nakano, J.; Miwa, Y.; Tsukada, T.; Kikuchi, M.; Kita, S.; Nemoto, Y.; Tsuji, H.; Jitsukawa, S.

    2002-12-01

    Type 316L(N) stainless steel of the international thermonuclear experimental reactor grade (316L(N)-IG SS) is being considered for the first wall/blanket module. Hot isostatic pressing (HIP) technique is expected for the fabrication of the module. To evaluate the integrity and susceptibility to stress corrosion cracking (SCC) of HIPed 316L(N)-IG SS, tensile tests in vacuum and slow strain rate tests in high temperature water were performed. Specimen with the HIPed joint had similar tensile properties to specimens of 316L(N)-IG SS, and did not show susceptibility to SCC in oxygenated water at 423 K. Thermally sensitized specimen was low susceptible to SCC even in the creviced condition. It is concluded that the tensile properties of HIPed SS are as high as those of the base alloy and the HIP process caused no deleterious effects.

  18. An optical coherence tomography (OCT)-based air jet indentation system for measuring the mechanical properties of soft tissues

    PubMed Central

    Huang, Yan-Ping; Zheng, Yong-Ping; Wang, Shu-Zhe; Chen, Zhong-Ping; Huang, Qing-Hua; He, Yong-Hong

    2010-01-01

    A novel noncontact indentation system with the combination of an air jet and optical coherence tomography (OCT) was presented in this paper for the quantitative measurement of the mechanical properties of soft tissues. The key idea of this method is to use a pressure-controlled air jet as an indenter to compress the soft tissue in a noncontact way and utilize the OCT signals to extract the deformation induced. This indentation system provides measurement and mapping of tissue elasticity for small specimens with high scanning speed. Experiments were performed on 27 silicone tissue-mimicking phantoms with different Young’s moduli, which were also measured by uniaxial compression tests. The regression coefficient of the indentation force to the indentation depth (N mm−1) was used as an indicator of the stiffness of tissue under air jet indentation. Results showed that the stiffness coefficients measured by the current system correlated well with the corresponding Young’s moduli obtained by conventional mechanical testing (r = 0.89, p < 0.001). Preliminary in vivo tests also showed that the change of soft tissue stiffness with and without the contraction of the underlying muscles in the hand could be differentiated by the current measurement. This system may have broad applications in tissue assessment and characterization where alterations of mechanical properties are involved, in particular with the potential of noncontact micro-indentation for tissues. PMID:20463843

  19. Immunotoxicological effects of JP-8 jet fuel exposure.

    PubMed

    Harris, D T; Sakiestewa, D; Robledo, R F; Witten, M

    1997-01-01

    Chronic exposure to jet fuel has been shown to have adverse effects on human liver function, to cause emotional dysfunction, to cause abnormal electroencephalograms, to cause shortened attention spans, and to decrease sensorimotor speed (3-5). Due to the decision by the United States Air Force to implement the widespread use of JP-8 jet fuel in its operations, a thorough understanding of its potential effects upon exposed personnel is both critical and necessary. Exposure to potential environmental toxicants such as JP-8 may have significant effects on host systems beyond those readily visible (e.g., physiology, cardiology, respiratory, etc.); e.g., the immune system. Significant changes in immune consequences, even if short-lived, may have serious consequences for the exposed host that may impinge affect susceptibility to infectious agents. Major alterations in immune function that are long-lasting may result in an increased likelihood of development and/or progression of cancer, as well as autoimmune diseases. In the current study mice were exposed for 1h/day for 7 days to varying concentrations of aerosolized JP-8 jet fuel to simulate occupational exposures. Twenty-four hours after the last exposure the mice were analyzed for effects on their immune systems. It was observed that even at exposure concentrations as low as 100 mg/m3 detrimental effects on the immune system occurred. Decreases in viable immune cell numbers and immune organ weights were found. Jet fuel exposure resulted in losses of different immune cell subpopulations depending upon the immune organ being examined. Further, JP-8 exposure resulted in significantly decreased immune function, as analyzed by mitogenesis assays. Suppressed immune function could not be overcome by the addition of exogenous growth factors known to stimulate immune function. Thus, short-term, low concentration exposure of mice to JP-8 jet fuel caused significant toxicological effects on the immune system. It appears that

  20. Cosmic jets

    NASA Technical Reports Server (NTRS)

    Rees, M. J.

    1986-01-01

    The evidence that active galactic nuclei produce collimated plasma jets is summarised. The strongest radio galaxies are probably energised by relativistic plasma jets generated by spinning black holes interacting with magnetic fields attached to infalling matter. Such objects can produce e(+)-e(-) plasma, and may be relevant to the acceleration of the highest-energy cosmic ray primaries. Small-scale counterparts of the jet phenomenon within our own galaxy are briefly reviewed.

  1. Interaction of argon and helium plasma jets and jets arrays with account for gravity

    NASA Astrophysics Data System (ADS)

    Babaeva, Natalia Yu.; Naidis, George V.; Panov, Vladislav A.; Wang, Ruixue; Zhao, Yong; Shao, Tao

    2018-06-01

    In this paper, we discuss results from an experimental and computational study of the properties of a single jet and two-tube jet arrays operating in argon and helium. The jets are positioned horizontally. It was shown in experiments that the helium plasma plume bends upward and the plumes in the two-tubes jet array tend to divert due to the jet-jet interaction. To investigate these potential interactions, a computational study was performed of one- and two-tube argon and helium jet arrays having variable spacing. The effects of buoyancy forces on the jet-to-jet interaction of the plasma plumes are also investigated. Velocities of ionization waves inside and outside the tubes are estimated and compared for the argon and helium ionization waves. We show that in helium jet-jet interactions primarily depend on the spacing between the tubes and on the buoyancy forces. The helium plumes tend to merge into one single stream before dissipating, while the argon plasma plumes are less sensitive to the spacing of the jet tubes.

  2. Jets in Planetary Atmospheres

    NASA Astrophysics Data System (ADS)

    Dowling, Tim

    2018-05-01

    Jet streams, "jets" for short, are remarkably coherent streams of air found in every major atmosphere. They have a profound effect on a planet's global circulation, and have been an enigma since the belts and zones of Jupiter were discovered in the 1600s. The study of jets, including what processes affect their size, strength, direction, shear stability, and predictability, are active areas of research in geophysical fluid dynamics. Jet research is multidisciplinary and global, involving collaborations between observers, experimentalists, numerical modelers, and applied mathematicians. Jets in atmospheres have strong analogies with shear instability in nonneutral plasmas, and these connections are highlighted throughout the article. The article begins with a description of four major challenges that jet researchers face: nonlinearity, non-intuitive wave physics, non-constant-coefficients, and copious nondimensional numbers. Then, two general fluid-dynamical tenets, the practice of rendering expressions dimensionally homogeneous (nondimensional), and the universal properties of shocks are applied to the open question of what controls the on-off switch of shear instability. The discussion progresses to how the physics of jets varies in equatorial, midlatitude, and polar regions, and how jets are observed to behave in each of these settings. The all-in-one conservation law of potential vorticity (PV), which combines the conservation laws of mass, momentum, and thermal energy into a single expression, is the common language of jet research. Earth and Uranus have weak retrograde equatorial jets, but most planets exhibit super-rotating equatorial jets, which require eddies to transport momentum up gradient in a non-intuitive manner. Jupiter and Saturn exhibit multiple alternating jets in their midlatitudes. The theory for why jets are invariably zonal (east-west orientated) is reviewed, and the particular challenges that Jupiter's sharp westward jets present to existing

  3. Fast Ss-Ilm a Computationally Efficient Algorithm to Discover Socially Important Locations

    NASA Astrophysics Data System (ADS)

    Dokuz, A. S.; Celik, M.

    2017-11-01

    Socially important locations are places which are frequently visited by social media users in their social media lifetime. Discovering socially important locations provide several valuable information about user behaviours on social media networking sites. However, discovering socially important locations are challenging due to data volume and dimensions, spatial and temporal calculations, location sparseness in social media datasets, and inefficiency of current algorithms. In the literature, several studies are conducted to discover important locations, however, the proposed approaches do not work in computationally efficient manner. In this study, we propose Fast SS-ILM algorithm by modifying the algorithm of SS-ILM to mine socially important locations efficiently. Experimental results show that proposed Fast SS-ILM algorithm decreases execution time of socially important locations discovery process up to 20 %.

  4. Jet noise suppression

    NASA Astrophysics Data System (ADS)

    Gliebe, P. R.; Brausch, J. F.; Majjigi, R. K.; Lee, R.

    1991-08-01

    The objectives of this chapter are to review and summarize the jet noise suppression technology, to provide a physical and theoretical model to explain the measured jet noise suppression characteristics of different concepts, and to provide a set of guidelines for evolving jet noise suppression designs. The underlying principle for all jet noise suppression devices is to enhance rapid mixing (i.e., diffusion) of the jet plume by geometric and aerothermodynamic means. In the case of supersonic jets, the shock-cell broadband noise reduction is effectively accomplished by the elimination or mitigation of the shock-cell structure. So far, the diffusion concepts have predominantly concentrated on jet momentum and energy (kinetic and thermal) diffusion, in that order, and have yielded better noise reduction than the simple conical nozzles. A critical technology issue that needs resolution is the effect of flight on the noise suppression potential of mechanical suppressor nozzles. A more thorough investigation of this mechanism is necessary for the successful development and design of an acceptable noise suppression device for future high-speed civil transports.

  5. Control of jet noise

    NASA Technical Reports Server (NTRS)

    Schreck, Stefan

    1992-01-01

    To investigate the possibility of active control of jet noise, knowledge of the noise generation mechanisms in natural jets is essential. Once these mechanisms are determined, active control can be used to manipulate the noise production processes. We investigated the evolution of the flow fields and the acoustic fields of rectangular and circular jets. A predominant flapping mode was found in the supersonic rectangular jets. We hope to increase the spreading of supersonic jets by active control of the flapping mode found in rectangular supersonic jets.

  6. Combinatorial gene editing in mammalian cells using ssODNs and TALENs

    NASA Astrophysics Data System (ADS)

    Strouse, Bryan; Bialk, Pawel; Niamat, Rohina A.; Rivera-Torres, Natalia; Kmiec, Eric B.

    2014-01-01

    The regulation of gene editing is being elucidated in mammalian cells and its potential as well as its limitations are becoming evident. ssODNs carry out gene editing by annealing to their complimentary sequence at the target site and acting as primers for replication fork extension. To effect a genetic change, a large amount of ssODN molecules must be introduced into cells and as such induce a Reduced Proliferation Phenotype (RPP), a phenomenon in which corrected cells do not proliferate. To overcome this limitation, we have used TAL-Effector Nucleases (TALENs) to increase the frequency, while reducing the amount of ssODN required to direct gene correction. This strategy resolves the problem and averts the serious effects of RPP. The efficiency of gene editing can be increased significantly if cells are targeted while they progress through S phase. Our studies define new reaction parameters that will help guide experimental strategies of gene editing.

  7. Protein dynamics during presynaptic complex assembly on individual ssDNA molecules

    PubMed Central

    Gibb, Bryan; Ye, Ling F.; Kwon, YoungHo; Niu, Hengyao; Sung, Patrick; Greene, Eric C.

    2014-01-01

    Homologous recombination is a conserved pathway for repairing double–stranded breaks, which are processed to yield single–stranded DNA overhangs that serve as platforms for presynaptic complex assembly. Here we use single–molecule imaging to reveal the interplay between Saccharomyce cerevisiae RPA, Rad52, and Rad51 during presynaptic complex assembly. We show that Rad52 binds RPA–ssDNA and suppresses RPA turnover, highlighting an unanticipated regulatory influence on protein dynamics. Rad51 binding extends the ssDNA, and Rad52–RPA clusters remain interspersed along the presynaptic complex. These clusters promote additional binding of RPA and Rad52. Together, our work illustrates the spatial and temporal progression of RPA and Rad52 association with the presynaptic complex, and reveals a novel RPA–Rad52–Rad51–ssDNA intermediate, which has implications for understanding how the activities of Rad52 and RPA are coordinated with Rad51 during the later stages recombination. PMID:25195049

  8. MeSS: A novel prognostic scale specific for pediatric well-differentiated thyroid cancer: a population-based, SEER outcomes study.

    PubMed

    Shayota, Brian J; Pawar, Shonali C; Chamberlain, Ronald S

    2013-09-01

    High-risk prognostic factors for adults with well-differentiated thyroid cancer (WDTC) have been well established, but the same is not true for pediatric patients. This study sought to determine whether validated adult prognostic systems are applicable to pediatric patients and to develop a novel prognostic scale that may better reflect outcomes in pediatric subgroups. We queried 62,007 cases of WDTC from the Surveillance, Epidemiology, and End Results (SEER) database (1973-2009) to identify 895 patients <20 years of age with WDTC. Data abstracted included age, gender, race, histology type, primary tumor size, cancer stage, and mortality. Odds ratio and 95% confidence intervals were set and data were analyzed with SAS version 9.2. Among 895 pediatric WDTC patients, the overall cause-specific mortality was 0.8%. The presence of distant metastasis was associated with the worst prognosis (P = .0045) followed by larger primary tumor size (P = .0135) and male gender (P = .0162). When classified into low-, moderate-, and high-risk categories according to the distant metastasis (Me), larger primary tumor size (S), and male sex (S) (MeSS) algorithm, mortality rates were 0%, 2.7%, and 23%, respectively. Commonly used prognostic indices for WDTC in adults do not reliably predict poor outcomes among pediatric patients. Rather, a system based on MeSS is more applicable to pediatric patients. Patients who exhibit a high MeSS score have a significantly worse overall survival than those who do not express any MeSS characteristics. Copyright © 2013 Mosby, Inc. All rights reserved.

  9. Mechanism of the formation of the RecA-ssDNA nucleoprotein filament structure: a coarse-grained approach.

    PubMed

    Mukherjee, Goutam; Pal, Arumay; Levy, Yaakov

    2017-11-21

    In prokaryotes, the RecA protein catalyzes the repair and strand exchange of double-stranded DNA. RecA binds to single-stranded DNA (ssDNA) and forms a presynaptic complex in which the protein polymerizes around the ssDNA to form a right-handed helical nucleoprotein filament structure. In the present work, the mechanism for the formation of the RecA-ssDNA filament structure is modeled using coarse-grained molecular dynamics simulations. Information from the X-ray structure was used to model the protein itself but not its interactions; the interactions between the protein and the ssDNA were modeled solely by electrostatic, aromatic, and repulsive energies. For the present study, the monomeric, dimeric, and trimeric units of RecA and 4, 8, and 11 NT-long ssDNA, respectively, were studied. Our results indicate that monomeric RecA is not sufficient for nucleoprotein filament formation; rather, dimeric RecA is the elementary binding unit, with higher multimeric units of RecA facilitating filament formation. Our results reveal that loop region flexibility at the primary binding site of RecA is essential for it to bind the incoming ssDNA, that the aromatic residues present in the loop region play an important role in ssDNA binding, and that ATP may play a role in guiding the ssDNA by changing the electrostatic potential of the RecA protein.

  10. Optimisation of a polygon mirror-based spectral filter for swept source optical coherence tomography (SS-OCT)

    NASA Astrophysics Data System (ADS)

    Everson, Michael; Duma, Virgil-Florin; Dobre, George

    2018-03-01

    Medical imaging using Optical Coherence Tomography (OCT) provides clinicians with 3D, high resolution reconstructions of microscopic structures, in depth. It has been initially developed for ophthalmology, in order to scan the retinas of patients to diagnose illness. The quality of the images depends upon their axial and lateral resolutions and the properties of the light being used. Research using a polygon mirror (PM) as a spectral filter in Swept Source OCT (SS-OCT) has resulted in a variety of different experimental arrangements. Although the application of PM-based SS-OCT sources has been successfully demonstrated, the combination of their components' fundamental properties and the overall impact they have on imaging performance is rarely reported. A more detailed examination of these properties would lead to a full description of their operation and to the best methods to employ if system performance is to be maximised. This work presents our current findings of on-going research into the optimisation of PM-based SS-OCT systems. A swept source spectral filter, consisting of a collimator, a transmission grating, a two-lens telescope and an off-axis PM with an end reflector mirror has been evaluated experimentally and compared with theoretical predictions. The system's performance has been compared for two different fibre collimators. Although the beam width on the grating is different for each of the two collimators, the spot size at the PM facet is made the same by selecting appropriate focal lengths. An improvement in the signal roll-off at the interferometer output of 1.0 dB/mm was obtained when using a 3.4 mm collimator compared to a 1.5 mm collimator.

  11. NExSS/NAI Joint ExoPAG SAG 16 Report on Remote Biosignatures for Exoplanets

    NASA Technical Reports Server (NTRS)

    Kiang, Nancy Y.; Parenteau, Mary Nicole; Domagal-Goldman, Shawn

    2017-01-01

    Future exoplanet observations will soon focus on the search for life beyond the Solar System. Exoplanet biosignatures to be sought are those with global, potentially detectable, impacts on a planet. Biosignatures occur in an environmental context in which geological, atmospheric, and stellar processes and interactions may work to enhance, suppress or mimic these biosignatures. Thus biosignature scienceis inherently interdisciplinary. Its advance is necessary to inform the design of the next flagship missions that will obtain spectra of habitable extrasolar planets. The NExSS NAI Joint Exoplanet Biosignatures Workshop Without Walls brought together the astrobiology, exoplanet, and mission concept communities to review, discuss, debate, and advance the science of remote detection of planetary biosignatures. The multi-meeting workshop began in June 2016, and was a process that engaged a broad range of experts across the interdisciplinary reaches of NASA's Nexus for Exoplanet System Science (NExSS) program, the NASA Astrobiology Institute (NAI), NASAs Exoplanet Exploration Program (ExEP), and international partners, such as the European Astrobiology Network Association (EANA) and Japans Earth Life Science Institute (ELSI). These groups spanned expertise in astronomy, planetary science, Earth sciences, heliophysics, biology, instrument mission development, and engineering.

  12. Parsec-scale jets and tori in seyfert galaxies

    NASA Astrophysics Data System (ADS)

    Roy, A. L.; Wrobel, J. M.; Wilson, A. S.; Ulvestad, J. S.; Norris, R. P.; Mundell, C. G.; Krichbaum, T. P.; Falcke, H.; Colbert, E. J. M.

    2001-01-01

    H. Falcke, T.P. Krichbaum, C.G. Mundell, J.S. Ulvestad, A.S. Wilson, J.M. Wrobel Active galaxies tend to be powerful or weak radio sources, and we still do not understand the underlying cause. Perhaps the engine is the same in both systems and the jet gets disrupted by dense interstellar medium in radio-quiet objects, or else the difference is intrinsic with jet power scaling with black hole spin. To distinguish, one can look for signs of interaction between the jet and the narrow-line region, and to measure the jet speed close to the jet base, before environmental effects become important. We find one-sided parsec-scale jet structures in Mrk 348, Mrk 231, NGC 4151, and NGC 5506 using VLBI, and we measure low jet speeds (typically <= 0.25 c). The one-sidedness probably is not due to Doppler boosting, but rather is probably free-free absorption. Plasma conditions required to produce the absorption are Ne >= 2 × 105 cm-3 assuming a path length of 0.1 pc, typical of that expected at the inner edge of the obscuring torus.

  13. Multi-specie isothermal flow calculations of widely-spaced co-axial jets in a confined sudden expansion, with the central jet dominant

    NASA Astrophysics Data System (ADS)

    Sturgess, G. J.; Syed, S. A.

    1982-06-01

    A numerical simulation is made of the flow in the Wright Aeronautical Propulsion Laboratory diffusion flame research combustor operating with a strong central jet of carbon dioxide in a weak and removed co-axial jet of air. The simulation is based on a finite difference solution of the time-average, steady-state, elliptic form of the Reynolds equations. Closure for these equations is provided by a two-equation turbulence model. Comparisons between measurements and predictions are made for centerline axial velocities and radial profiles of CO2 concentration. Earlier findings for a single specie, constant density, single jet flow that a large expansion ratio confined jet behaves initially as if it were unconfined, are confirmed for the multiple-specie, variable density, multiple-jet system. The lack of universality in the turbulence model constants and the turbulent Schmidt/Prandtl number is discussed.

  14. PIV Measurements of Supersonic Internally-Mixed Dual-Stream Jets

    NASA Technical Reports Server (NTRS)

    Bridges, James E.; Wernet, Mark P.

    2012-01-01

    While externally mixed, or separate flow, nozzle systems are most common in high bypass-ratio aircraft, they are not as attractive for use in lower bypass-ratio systems and on aircraft that will fly supersonically. The noise of such propulsion systems is also dominated by jet noise, making the study and noise reduction of these exhaust systems very important, both for military aircraft and future civilian supersonic aircraft. This paper presents particle image velocimetry of internally mixed nozzle with different area ratios between core and bypass, and nozzles that are ideally expanded and convergent. Such configurations independently control the geometry of the internal mixing layer and of the external shock structure. These allow exploration of the impact of shocks on the turbulent mixing layers, the impact of bypass ratio on broadband shock noise and mixing noise, and the impact of temperature on the turbulent flow field. At the 2009 AIAA/CEAS Aeroacoustics Conference the authors presented data and analysis from a series of tests that looked at the acoustics of supersonic jets from internally mixed nozzles. In that paper the broadband shock and mixing noise components of the jet noise were independently manipulated by holding Mach number constant while varying bypass ratio and jet temperature. Significant portions of that analysis was predicated on assumptions regarding the flow fields of these jets, both shock structure and turbulence. In this paper we add to that analysis by presenting particle image velocimetry measurements of the flow fields of many of those jets. In addition, the turbulent velocity data documented here will be very useful for validation of computational flow codes that are being developed to design advanced nozzles for future aircraft.

  15. PREFACE: The 4th Symposium on the Mechanics of Slender Structures (MoSS2013)

    NASA Astrophysics Data System (ADS)

    Cao, Dengqing; Kaczmarczyk, Stefan

    2013-07-01

    This volume of Journal of Physics: Conference Series contains papers presented at the 4th Symposium on the Mechanics of Slender Structures (MoSS2013) run under the auspices of the Institute of Physics Applied Mechanics Group and hosted by Harbin Institute of Technology (China) from 7-9 January 2013. The conference has been organized in collaboration with the Technical Committee on Vibration and Sound of the American Society of Mechanical Engineers and follows a one day seminar on Ropes, Cables, Belts and Chains: Theory and Applications and the MoSS2006 symposium held at the University of Northampton (UK) in 2004 and 2006, respectively, the MoSS2008 symposium held at the University of Maryland Baltimore County (USA) in 2008 and the MoSS2010 symposium hosted by Mondragon University and held in San Sebastian (Spain) in 2010. The remit of the Symposium on the Mechanics of Slender Structures series involves a broad range of scientific areas. Applications of slender structures include terrestrial, marine and space systems. Moving elastic elements such as ropes, cables, belts and tethers are pivotal components of many engineering systems. Their lengths often vary when the system is in operation. The applications include vertical transportation installations and, more recently, space tether propulsion systems. Traction drive elevator installations employ ropes and belts of variable length as a means of suspension, and also for the compensation of tensile forces over the traction sheave. In cranes and mine hoists, cables and ropes are subject to length variation in order to carry payloads. Tethers experiencing extension and retraction are important components of offshore and marine installations, as well as being proposed for a variety of different space vehicle propulsion systems based on different applications of momentum exchange and electrodynamic interactions with planetary magnetic fields. Furthermore, cables and slender rods are used extensively in civil engineering

  16. Jet multiplicity in the proto-binary system NGC 1333-IRAS4A. The detailed CALYPSO IRAM-PdBI view

    NASA Astrophysics Data System (ADS)

    Santangelo, G.; Codella, C.; Cabrit, S.; Maury, A. J.; Gueth, F.; Maret, S.; Lefloch, B.; Belloche, A.; André, Ph.; Hennebelle, P.; Anderl, S.; Podio, L.; Testi, L.

    2015-12-01

    Context. Owing to the paucity of sub-arcsecond (sub)mm observations required to probe the innermost regions of newly forming protostars, several fundamental questions are still being debated, such as the existence and coevality of close multiple systems. Aims: We study the physical and chemical properties of the jets and protostellar sources in the NGC 1333-IRAS4A proto-binary system using continuum emission and molecular tracers of shocked gas. Methods: We observed NGC 1333-IRAS4A in the SiO(6-5), SO(65-54), and CO(2-1) lines and the continuum emission at 1.3, 1.4, and 3 mm using the IRAM Plateau de Bure Interferometer in the framework of the CALYPSO large program. Results: We clearly disentangle for the first time the outflow emission from the two sources A1 and A2. The two protostellar jets have very different properties: the A1 jet is faster, has a short dynamical timescale (≲103 yr), and is associated with H2 shocked emission, whereas the A2 jet, which dominates the large-scale emission, is associated with diffuse emission, bends, and emits at slower velocities. The observed bending of the A2 jet is consistent with the change of propagation direction observed at large scale and suggests jet precession on very short timescales (~200-600 yr). In addition, a chemically rich spectrum with emission from several complex organic molecules (e.g. HCOOH, CH3OCHO, CH3OCH3) is only detected towards A2. Finally, very high-velocity shocked emission (~50 km s-1) is observed along the A1 jet. An LTE analysis shows that SiO, SO, and H2CO abundances in the gas phase are enhanced up to (3-4)×10-7, (1.4-1.7)×10-6, and (3-7.9)×10-7, respectively. Conclusions: The intrinsic different properties of the jets and driving sources in NGC 1333-IRAS4A suggest different evolutionary stages for the two protostars, with A1 being younger than A2, in a very early stage of star formation previous to the hot-corino phase. Based on observations carried out with the IRAM Plateau de Bure

  17. Aeroacoustic Experiments with Twin Jets

    NASA Technical Reports Server (NTRS)

    Bozak, Richard F.; Henderson, Brenda S.

    2012-01-01

    While the noise produced by a single jet is azimuthally symmetric, multiple jets produce azimuthally varying far-field noise. The ability of one jet to shield another reduces the noise radiated in the plane of the jets, while often increasing the noise radiated out of the plane containing the jets. The present study investigates the shielding potential of twin jet configurations over subsonic and over-expanded supersonic jet conditions with simulated forward flight. The experiments were conducted with 2 in. throat diameter nozzles at four jet spacings from 2.6d to 5.5d in center-to-center distance, where d is the nozzle throat diameter. The current study found a maximum of 3 dB reduction in overall sound pressure level relative to two incoherent jets in the peak jet noise direction in the plane containing the jets. However, an increase of 3 dB was found perpendicular to the plane containing the jets. In the sideline direction, shielding is observed for all jet spacings in this study.

  18. Effects of in utero JP-8 jet fuel exposure on the immune systems of pregnant and newborn mice.

    PubMed

    Harris, D T; Sakiestewa, D; He, X; Titone, D; Witten, M

    2007-10-01

    The US Air Force has implemented the widespread use of JP-8 jet fuel in its operations, although a thorough understanding of its potential effects upon exposed personnel is unclear. Previous work has reported that JP-8 exposure is immunosuppressive. In the present study, the effects of in-utero JP-8 jet fuel exposure in mice were examined to ascertain any potential effects of jet fuel exposure on female personnel and their offspring. Exposure by the aerosol route (at 1000 mg/m3 for 1 h/day; similar to exposures incurred by flight line personnel) commencing during the first (d7 to birth) or last (d15 to birth) trimester of pregnancy was analyzed. It was observed that even 6-8 weeks after the last jet fuel exposure that the immune system of the dams (mother of newborn mice) was affected (in accordance with previous reports on normal mice). That is, thymus organ weights and viable cell numbers were decreased, and immune function was depressed. A decrease in viable male offspring was found, notably more pronounced when exposure started during the first trimester of pregnancy. Regardless of when jet fuel exposure started, all newborn mice (at 6-8 weeks after birth) reported significant immunosuppression. That is, newborn pups displayed decreased immune organ weights, decreased viable immune cell numbers and suppressed immune function. When the data were analyzed in relation to the respective mothers of the pups the data were more pronounced. Although all jet fuel-exposed pups were immunosuppressed as compared with control pups, male offspring were more affected by jet fuel exposure than female pups. Furthermore, the immune function of the newborn mice was directly correlated to the immune function of their respective mothers. That is, mothers showing the lowest immune function after JP-8 exposure gave birth to pups displaying the greatest effects of jet fuel exposure on immune function. Mothers who showed the highest levels of immune function after in-utero JP-8

  19. Studies of jet mass in dijet and W/Z + jet events

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chatrchyan, S.; Khachatryan, V.; Sirunyan, A. M.

    Invariant mass spectra for jets reconstructed using the anti-kt and Cambridge-Aachen algorithms are studied for different jet "grooming" techniques in data corresponding to an integrated luminosity of 5 inverse femtobarns, recorded with the CMS detector in proton-proton collisions at the LHC at a center-of-mass energy of 7 TeV. Leading-order QCD predictions for inclusive dijet and W/Z+jet production combined with parton-shower Monte Carlo models are found to agree overall with the data, and the agreement improves with the implementation of jet grooming methods used to distinguish merged jets of large transverse momentum from softer QCD gluon radiation.

  20. Solar Active Region Coronal Jets. II. Triggering and Evolution of Violent Jets

    NASA Astrophysics Data System (ADS)

    Sterling, Alphonse C.; Moore, Ronald L.; Falconer, David A.; Panesar, Navdeep K.; Martinez, Francisco

    2017-07-01

    We study a series of X-ray-bright, rapidly evolving active region coronal jets outside the leading sunspot of AR 12259, using Hinode/X-ray telescope, Solar Dynamics Observatory (SDO)/Atmospheric Imaging Assembly (AIA) and Helioseismic and Magnetic Imager (HMI), and Interface Region Imaging Spectrograph (IRIS) data. The detailed evolution of such rapidly evolving “violent” jets remained a mystery after our previous investigation of active region jets. The jets we investigate here erupt from three localized subregions, each containing a rapidly evolving (positive) minority-polarity magnetic-flux patch bathed in a (majority) negative-polarity magnetic-flux background. At least several of the jets begin with eruptions of what appear to be thin (thickness ≲ 2\\prime\\prime ) miniature-filament (minifilament) “strands” from a magnetic neutral line where magnetic flux cancelation is ongoing, consistent with the magnetic configuration presented for coronal-hole jets in Sterling et al. (2016). Some jets strands are difficult/impossible to detect, perhaps due to, e.g., their thinness, obscuration by surrounding bright or dark features, or the absence of erupting cool-material minifilaments in those jets. Tracing in detail the flux evolution in one of the subregions, we find bursts of strong jetting occurring only during times of strong flux cancelation. Averaged over seven jetting episodes, the cancelation rate was ˜ 1.5× {10}19 Mx hr-1. An average flux of ˜ 5× {10}18 Mx canceled prior to each episode, arguably building up ˜1028-1029 erg of free magnetic energy per jet. From these and previous observations, we infer that flux cancelation is the fundamental process responsible for the pre-eruption build up and triggering of at least many jets in active regions, quiet regions, and coronal holes.

  1. Tangential synthetic jets for separation control

    NASA Astrophysics Data System (ADS)

    Esmaeili Monir, H.; Tadjfar, M.; Bakhtian, A.

    2014-02-01

    A numerical study of separation control has been made to investigate aerodynamic characteristics of a NACA23012 airfoil with a tangential synthetic jet. Simulations are carried out at the chord Reynolds number of Re=2.19×106. The present approach relies on solving the Unsteady Reynolds-Averaged Navier-Stokes (URANS) equations. The turbulence model used in the present computation is the Spalart-Allmaras one-equation model. All computations are performed with a finite volume based code. Stall characteristics are significantly improved by controlling the formation of separation vortices in the flow. We placed the synthetic jet at the 12% chord, xj=0.12c, where we expected the separation to occur. Two distinct jet oscillating frequencies: Fj+=0.159 and Fj+=1 were considered. We studied the effect of blowing ratio, Vj/U∞, where it was varied from 0 to 5. The inclined angle of the synthetic jet was varied from αj=0° up to αj=83°. For the non-zero inclined angles, the local maximum in the aerodynamic performance, Cl/Cd, of 6.89 was found for the inclined angle of about 43°. In the present method, by means of creating a dent on the airfoil, linear momentum is transferred to the flow system in tangential direction to the airfoil surface. Thus the absolute maximum of 11.19 was found for the tangential synthetic jet at the inclined angle of the jet of 0°. The mechanisms involved for a tangential jet appear to behave linearly, as by multiplying the activation frequency of the jet by a factor produces the same multiplication factor in the resulting frequency in the flow. However, the mechanisms involved in the non-zero inclined angle cases behave nonlinearly when the activation frequency is multiplied.

  2. Simulations of Solar Jets Confined by Coronal Loops

    NASA Technical Reports Server (NTRS)

    Wyper, P. F.; De Vore, C. R.

    2016-01-01

    Coronal jets are collimated, dynamic events that occur over a broad range of spatial scales in the solar corona. In the open magnetic field of coronal holes, jets form quasi-radial spires that can extend far out into the heliosphere, while in closed-field regions the jet outflows are confined to the corona. We explore the application of the embedded-bipole model to jets occurring in closed coronal loops. In this model, magnetic free energy is injected slowly by footpoint motions that introduce twist within the closed dome of the jet source region, and is released rapidly by the onset of an ideal kink-like instability. Two length scales characterize the system: the width (N) of the jet source region and the footpoint separation (L) of the coronal loop that envelops the jet source. We find that both the conditions for initiation and the subsequent dynamics are highly sensitive to the ratio L/N. The longest-lasting and most energetic jets occur along long coronal loops with large L/N ratios, and share many of the features of open-field jets, while smaller L/N ratios produce shorter-duration, less energetic jets that are affected by reflections from the far-loop footpoint. We quantify the transition between these behaviors and show that our model replicates key qualitative and quantitative aspects of both quiet Sun and active-region loop jets. We also find that there connection between the closed dome and surrounding coronal loop is very extensive: the cumulative reconnected flux at least matches the total flux beneath the dome for small L/N, and is more than double that value for large L/N.

  3. SIMULATIONS OF SOLAR JETS CONFINED BY CORONAL LOOPS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wyper, P. F.; DeVore, C. R., E-mail: peter.f.wyper@nasa.gov, E-mail: c.richard.devore@nasa.gov

    Coronal jets are collimated, dynamic events that occur over a broad range of spatial scales in the solar corona. In the open magnetic field of coronal holes, jets form quasi-radial spires that can extend far out into the heliosphere, while in closed-field regions the jet outflows are confined to the corona. We explore the application of the embedded-bipole model to jets occurring in closed coronal loops. In this model, magnetic free energy is injected slowly by footpoint motions that introduce twist within the closed dome of the jet source region, and is released rapidly by the onset of an idealmore » kink-like instability. Two length scales characterize the system: the width (N) of the jet source region and the footpoint separation (L) of the coronal loop that envelops the jet source. We find that both the conditions for initiation and the subsequent dynamics are highly sensitive to the ratio L/N. The longest-lasting and most energetic jets occur along long coronal loops with large L/N ratios, and share many of the features of open-field jets, while smaller L/N ratios produce shorter-duration, less energetic jets that are affected by reflections from the far-loop footpoint. We quantify the transition between these behaviors and show that our model replicates key qualitative and quantitative aspects of both quiet Sun and active-region loop jets. We also find that the reconnection between the closed dome and surrounding coronal loop is very extensive: the cumulative reconnected flux at least matches the total flux beneath the dome for small L/N, and is more than double that value for large L/N.« less

  4. Multiple jet study

    NASA Technical Reports Server (NTRS)

    Walker, R. E.; Kors, D. L.

    1973-01-01

    Test data is presented which allows determination of jet penetration and mixing of multiple cold air jets into a ducted subsonic heated mainstream flow. Jet-to-mainstream momentum flux ratios ranged from 6 to 60. Temperature profile data is presented at various duct locations up to 24 orifice diameters downstream of the plane of jet injection. Except for two configurations, all geometries investigated had a single row of constant diameter orifices located transverse to the main flow direction. Orifice size and spacing between orifices were varied. Both of these were found to have a significant effect on jet penetration and mixing. The best mixing of the hot and cold streams was achieved with duct height.

  5. Jet simulations and gamma-ray burst afterglow jet breaks

    NASA Astrophysics Data System (ADS)

    van Eerten, H. J.; Meliani, Z.; Wijers, R. A. M. J.; Keppens, R.

    2011-01-01

    The conventional derivation of the gamma-ray burst afterglow jet break time uses only the blast wave fluid Lorentz factor and therefore leads to an achromatic break. We show that in general gamma-ray burst afterglow jet breaks are chromatic across the self-absorption break. Depending on circumstances, the radio jet break may be postponed significantly. Using high-accuracy adaptive mesh fluid simulations in one dimension, coupled to a detailed synchrotron radiation code, we demonstrate that this is true even for the standard fireball model and hard-edged jets. We confirm these effects with a simulation in two dimensions. The frequency dependence of the jet break is a result of the angle dependence of the emission, the changing optical depth in the self-absorbed regime and the shape of the synchrotron spectrum in general. In the optically thin case the conventional analysis systematically overestimates the jet break time, leading to inferred opening angles that are underestimated by a factor of ˜1.3 and explosion energies that are underestimated by a factor of ˜1.7, for explosions in a homogeneous environment. The methods presented in this paper can be applied to adaptive mesh simulations of arbitrary relativistic fluid flows. All analysis presented here makes the usual assumption of an on-axis observer.

  6. Mixing augmentation of transverse hydrogen jet by injection of micro air jets in supersonic crossflow

    NASA Astrophysics Data System (ADS)

    Anazadehsayed, A.; Barzegar Gerdroodbary, M.; Amini, Y.; Moradi, R.

    2017-08-01

    In this study, the influences of the micro air jet on the mixing of the sonic transverse hydrogen through micro-jets subjected to a supersonic crossflow are investigated. A three-dimensional numerical study has been performed to reveal the affects of micro air jet on mixing of the hydrogen jet in a Mach 4.0 crossflow with a global equivalence ratio of 0.5. Parametric studies were conducted on the various air jet conditions by using the Reynolds-averaged Navier-Stokes equations with Menter's Shear Stress Transport (SST) turbulence model. Complex jet interactions were found in the downstream region with a variety of flow features depending upon the angle of micro air jet. These flow features were found to have subtle effects on the mixing of hydrogen jets. Results indicate a different flow structure as air jet is presented in the downstream of the fuel jet. According to the results, without air, mixing occurs at a low rate. When the air jet is presented in the downstream of fuel jet, significant increase (up to 300%) occurs in the mixing performance of the hydrogen jet at downstream. In multi fuel jets, the mixing performance of the fuel jet is increased more than 200% when the micro air jet is injected. Consequently, an enhanced mixing zone occurs downstream of the injection slots which leads to flame-holding.

  7. The oblique impingement of an axisymmetric jet. [flow characteristics of jet flow over flat plates

    NASA Technical Reports Server (NTRS)

    Foss, J. F.; Kleis, S. J.

    1976-01-01

    The mechanics of the oblique impingement of an axisymmetric jet on a plane surface are examined in detail. The stagnation point is discussed. A schematic drawing of the problem and coordinate system used to describe the flow field are given. The kinematic features of the flow above the plate are examined in the context of the conservation of mass, the vorticity of the jet, and the vorticity introduced by the jetplate interaction. The dynamic features of the flow are examined in terms of the surface pressure distribution and the cause-effect relationships which exist between the pressure and velocity/vorticity distributions. Flow calculations performed are given. The investigation is relevant to the flow resulting from the interaction of the propulsion jet with the main airfoil (STOL aircraft), and is appropriate to an over- or under- wing configuration.

  8. Relativistic jets without large-scale magnetic fields

    NASA Astrophysics Data System (ADS)

    Parfrey, K.; Giannios, D.; Beloborodov, A.

    2014-07-01

    The canonical model of relativistic jets from black holes requires a large-scale ordered magnetic field to provide a significant magnetic flux through the ergosphere--in the Blandford-Znajek process, the jet power scales with the square of the magnetic flux. In many jet systems the presence of the required flux in the environment of the central engine is questionable. I will describe an alternative scenario, in which jets are produced by the continuous sequential accretion of small magnetic loops. The magnetic energy stored in these coronal flux systems is amplified by the differential rotation of the accretion disc and by the rotating spacetime of the black hole, leading to runaway field line inflation, magnetic reconnection in thin current layers, and the ejection of discrete bubbles of Poynting-flux-dominated plasma. For illustration I will show the results of general-relativistic force-free electrodynamic simulations of rotating black hole coronae, performed using a new resistivity model. The dissipation of magnetic energy by coronal reconnection events, as demonstrated in these simulations, is a potential source of the observed high-energy emission from accreting compact objects.

  9. Rosetta Comet Spreads its Jets

    NASA Image and Video Library

    2014-10-24

    This image was taken by the Optical, Spectroscopic, and Infrared Remote Imaging System, Rosetta main onboard scientific imaging system, on Sept. 10, 2014. Jets of cometary activity can be seen along almost the entire body of the comet. http://photojournal.jpl.nasa.gov/catalog/PIA18886

  10. Supramolecular order following binding of the dichroic birefringent sulfonic dye Ponceau SS to collagen fibers.

    PubMed

    Vidal, B C; Mello, M L S

    2005-06-15

    The optical anisotropies (linear dichroism or LD and birefringence) of crystalline aggregates of the sulfonic azo-dye Ponceau SS and of dye complexed with chicken tendon collagen fibers were investigated in order to assess their polarizing properties and similarity to liquid crystals. In some experiments, the staining was preceded by treatment with picric acid. Crystalline fibrous aggregates of the dye had a negative LD, and their electronic transitions were oriented perpendicular to the filamentary structures. The binding of Ponceau SS molecules to the collagen fibers altered the LD signal, with variations in the fiber orientation affecting the resulting dichroic ratios. The long axis of the rod-like dye molecule was assumed to be bound in register, parallel to the collagen fiber. Picric acid did not affect the oriented binding of the azo dye to collagen fibers. There were differences in the optical anisotropy of Ponceau SS-stained tendons from 21-day-old and 41-day-old chickens, indicating that Ponceau SS was able to distinguish between different ordered states of macromolecular aggregation in chicken tendon collagen fibers. In the presence of dichroic rod-like azo-dye molecules such as Ponceau SS, collagen also formed structures with a much higher degree of orientation. The presence of LD in the Ponceau SS-collagen complex even in unpolarized light indicated that this complex can act as a polarizer. Copyright 2005 Wiley Periodicals, Inc.

  11. Hydrodynamical Simulations of the Jet in the Symbiotic Star MWC 560. 3; Application to X-ray Jets in Symbiotic Stars

    NASA Technical Reports Server (NTRS)

    Stute, Matthias; Sahai, Raghvendra

    2007-01-01

    In Papers I and II in this series, we presented hydrodynamical simulations of jet models with parameters representative of the symbiotic system MWC 560. These were simulations of a pulsed, initially underdense jet in a high-density ambient medium. Since the pulsed emission of the jet creates internal shocks and since the jet velocity is very high, the jet bow shock and the internal shocks are heated to high temperatures and should therefore emit X-ray radiation. In this paper, we investigate in detail the X-ray properties of the jets in our models. We have focused our study on the total X-ray luminosity and its temporal variability, the resulting spectra, and the spatial distribution of the emission. Temperature and density maps from our hydrodynamical simulations with radiative cooling presented in the second paper are used, together with emissivities calculated with the atomic database ATOMDB. The jets in our models show extended and variable X-ray emission, which can be characterized as a sum of hot and warm components with temperatures that are consistent with observations of CH Cyg and R Aqr. The X-ray spectra of our model jets show emission-line features that correspond to observed features in the spectra of CH Cyg. The innermost parts of our pulsed jets show iron line emission in the 6.4-6.7 keV range, which may explain such emission from the central source in R Aqr. We conclude that MWC 560 should be detectable with Chandra or XMM-Newton, and such X-ray observations will prove crucial for understanding jets in symbiotic stars.

  12. Jet production in high Q 2 deep-inelastic ep scattering at HERA

    NASA Astrophysics Data System (ADS)

    Derrick, M.; Krakauer, D.; Magill, S.; Mikunas, D.; Musgrave, B.; Repond, J.; Stanek, R.; Talaga, R. L.; Zhang, H.; Avad, R.; Bari, G.; Basile, M.; Bellagamba, L.; Boscherini, D.; Bruni, A.; Bruni, G.; Bruni, P.; Romeo, G. Cara; Castellini, G.; Chiarini, M.; Cifarelli, L.; Cindolo, F.; Contin, A.; Corradi, M.; Gialas, I.; Giusti, P.; Iacobucci, G.; Laurenti, G.; Levi, G.; Margotti, A.; Massam, T.; Nania, R.; Nemoz, C.; Palmonari, E.; Polini, A.; Sartorelli, G.; Timellini, R.; Garcia, Y. Zamora; Zichichi, A.; Bargende, A.; Crittenden, J.; Desch, K.; Diekmann, B.; Doeker, T.; Eckert, M.; Feld, L.; Frey, A.; Geerts, M.; Geitz, G.; Grothe, M.; Haas, T.; Hartmann, H.; Haun, D.; Heinloth, K.; Hilger, E.; Jakob, H.-P.; Katz, U. F.; Mari, S. M.; Mass, A.; Mengel, S.; Mollen, J.; Paul, E.; Rembser, Ch.; Schattevoy, R.; Schramm, D.; Stamm, J.; Wedemeyer, R.; Campbell-Robson, S.; Cassidy, A.; Dyce, N.; Foster, B.; George, S.; Gilmore, R.; Heath, G. P.; Heath, H. F.; Llewellyn, T. J.; Morgado, C. J. S.; Norman, D. J. P.; O'Mara, J. A.; Tapper, R. I.; Wilson, S. S.; Yoshida, R.; Rau, R. R.; Arneodo, M.; Iannotti, L.; Schioppa, M.; Susinno, G.; Bernstein, A.; Caldwell, A.; Parsons, J. A.; Ritz, S.; Sciulli, F.; Straub, P. B.; Wai, L.; Yang, S.; Zhu, Q.; Borzemski, P.; Chwastowski, J.; Eskreys, A.; Piotrzkowski, K.; Zachara, M.; Zawiejski, L.; Adamczyk, L.; Bednarek, B.; Eskreys, K.; Jeleń, K.; Kisielewska, D.; Kowalski, T.; Rulikowska-Zarębska, E.; Suszycki, L.; Zając, J.; Kotański, A.; Przybycień, M.; Bauerdick, I. A. T.; Behrens, U.; Beier, H.; Bienlein, J. K.; Coldewey, C.; Deppe, O.; Desler, K.; Drews, G.; Flasiński, M.; Gilkinson, D. J.; Glasman, C.; Göttlicher, P.; Große-Knetter, J.; Gutjahr, B.; Hain, W.; Hasell, D.; Heßling, H.; Hultschig, H.; Iga, Y.; Joos, P.; Kasemann, M.; Klanner, R.; Koch, W.; Köpke, L.; Kötz, U.; Kowalski, H.; Labs, J.; Ladage, A.; Löhr, B.; Löwe, M.; Lüke, D.; Mańczak, O.; Ng, J. S. T.; Nickel, S.; Notz, D.; Ohrenberg, K.; Roco, M.; Rohde, M.; Roldán, J.; Schneekloth, U.; Schulz, W.; Selonke, F.; Stiliaris, E.; Surrow, B.; Voß, T.; Westphal, D.; Wolf, G.; Youngman, C.; Zhou, J. F.; Grabosch, H. J.; Kharchilava, A.; Leich, A.; Mattingly, M.; Meyer, A.; Schlenstedt, S.; Wulff, N.; Barbagli, G.; Pelfer, P.; Anzivino, G.; Maccarrone, G.; de Pasquale, S.; Votano, L.; Bamberger, A.; Eisenhardt, S.; Freidhof, A.; Söldner-Rembold, S.; Schroeder, J.; Trefzger, T.; Brook, N. H.; Bussey, P. J.; Doyle, A. T.; Fleck, I.; Saxon, D. H.; Utley, M. L.; Wilson, A. S.; Dannemann, A.; Holm, U.; Horstmann, D.; Neumann, T.; Sinkus, R.; Wick, K.; Badura, E.; Burow, B. D.; Hagge, L.; Lohrmann, E.; Mainusch, J.; Milewski, J.; Nakahata, M.; Pavel, N.; Poelz, G.; Schott, W.; Zetsche, F.; Bacon, T. C.; Butterworth, I.; Gallo, E.; Harris, V. L.; Hung, B. Y. H.; Long, K. R.; Miller, D. B.; Morawitz, P. P. O.; Prinias, A.; Sedgbeer, J. K.; Whitfield, A. F.; Mallik, U.; McCliment, E.; Wang, M. Z.; Wang, S. M.; Wu, J. T.; Zhang, Y.; Cloth, P.; Filges, D.; An, S. H.; Hong, S. M.; Nam, S. W.; Park, S. K.; Suh, M. H.; Yon, S. H.; Imlay, R.; Kartik, S.; Kim, H.-J.; McNeil, R. R.; Metcalf, W.; Nadendla, V. K.; Barreiro, F.; Cases, G.; Graciani, R.; Hernández, J. M.; Hervás, L.; Labarga, L.; Del Peso, J.; Puga, J.; Terron, J.; de Trocóniz, J. F.; Smith, G. R.; Corriveau, F.; Hanna, D. S.; Hartmann, J.; Hung, L. W.; Lim, J. N.; Matthews, C. G.; Patel, P. M.; Sinclair, L. E.; Stairs, D. G.; Laurent, M. St.; Ullmann, R.; Zacek, G.; Bashkirov, V.; Dolgoshein, B. A.; Stifutkin, A.; Bashindzhagyan, G. L.; Ermolov, P. F.; Gladilin, L. K.; Golubkov, Y. A.; Kobrin, V. D.; Kuzmin, V. A.; Proskuryakov, A. S.; Savin, A. A.; Shcheglova, L. M.; Solomin, A. N.; Zotov, N. P.; Botje, M.; Chlebana, F.; Dake, A.; Engelen, J.; de Kamps, M.; Kooijman, P.; Kruse, A.; Tiecke, H.; Verkerke, W.; Vreeswijk, M.; Wiggers, L.; de Wolf, E.; van Woudenberg, R.; Acosta, D.; Bylsma, B.; Durkin, L. S.; Honscheid, K.; Li, C.; Ling, T. Y.; McLean, K. W.; Murray, W. N.; Park, I. H.; Romanowski, T. A.; Seidlein, R.; Bailey, D. S.; Blair, G. A.; Byrne, A.; Cashmore, R. J.; Cooper-Sarkar, A. M.; Daniels, D.; Devenish, R. C. E.; Harnew, N.; Lancaster, M.; Luffman, P. E.; Lindemann, L.; McFall, J. D.; Nath, C.; Noyes, V. A.; Quadt, A.; Uijterwaal, H.; Walczak, R.; Wilson, F. F.; Yip, T.; Abbiendi, G.; Bertolin, A.; Brugnera, R.; Carlin, R.; Dal Corso, F.; de Giorgi, M.; Dosselli, U.; Limentani, S.; Morandin, M.; Posocco, M.; Stanco, L.; Stroili, R.; Voci, C.; Bulmahn, J.; Butterworth, J. M.; Feild, R. G.; Oh, B. Y.; Whitmore, J. J.; D'Agostini, G.; Marini, G.; Nigro, A.; Tassi, E.; Hart, J. C.; McCubbin, N. A.; Prytz, K.; Shah, T. P.; Short, T. L.; Barberis, L.; Cartiglia, N.; Dubbs, T.; Heusch, C.; van Hook, M.; Hubbard, B.; Lockman, W.; Rahn, J. T.; Sadrozinski, H. F.-W.; Seiden, A.; Biltzinger, J.; Seifert, R. J.; Walenta, A. H.; Zech, G.; Abramowicz, H.; Briskin, G.; Dagan, S.; Levy, A.; Hasegawa, T.; Hazumi, M.; Ishii, T.; Kuze, M.; Mine, S.; Nagasawa, Y.; Nakao, M.; Suzuki, I.; Tokushuku, K.; Yamada, S.; Yamazaki, Y.; Chiba, M.; Hamatsu, R.; Hirose, T.; Homma, K.; Kitamura, S.; Nakamitsu, Y.; Yamauchi, K.; Cirio, R.; Costa, M.; Ferrero, M. I.; Lamberti, L.; Maselli, S.; Peroni, C.; Sacchi, R.; Solano, A.; Staiano, A.; Dardo, M.; Bailey, D. C.; Bandyopadhyay, D.; Benard, F.; Brkic, M.; Crombie, M. B.; Gingrich, D. M.; Hartner, G. F.; Joo, K. K.; Levman, G. M.; Martin, J. F.; Orr, R. S.; Sampson, C. R.; Teuscher, R. J.; Catterall, C. D.; Jones, T. W.; Kaziewicz, P. B.; Lane, J. B.; Saunders, R. L.; Shulman, J.; Blankenship, K.; Kochocki, J.; Lu, B.; Mo, L. W.; Bogusz, W.; Charchula, K.; Ciborowski, J.; Gajewski, J.; Grzelak, G.; Kasprzak, M.; Krzyżanowski, M.; Muchorowski, K.; Nowak, R. J.; Pawlak, J. M.; Tymieniecka, T.; Wróblewski, A. K.; Zakrzewski, J. A.; Żarnecki, A. F.; Adamus, M.; Eisenberg, Y.; Karshon, U.; Revel, D.; Zer-Zion, D.; Ali, I.; Badgett, W. F.; Behrens, B.; Dasu, S.; Fordham, C.; Foudas, C.; Goussiou, A.; Loveless, R. J.; Reeder, D. D.; Silverstein, S.; Smith, W. H.; Vaiciulis, A.; Wodarczyk, M.; Tsurugai, T.; Bhadra, S.; Cardy, M. L.; Fagerstroem, C.-P.; Frisken, W. R.; Furutani, K. M.; Khakzad, M.; Schmidke, W. B.

    1995-03-01

    Two-jet production in deep-inelastic electron-proton scattering has been studied for 160< Q 2<1280 GeV2, 0.01< x<0.1 and 0.04< y<0.95 with the ZEUS detector at HERA. The kinematic properties of the jets and the jet production rates are presented. The partonic scaling variables of the two-jet system and the rate of two-jet production are compared to perturbative next-to-leading order QCD calculations.

  13. A computational model for three-dimensional incompressible wall jets with large cross flow

    NASA Technical Reports Server (NTRS)

    Murphy, W. D.; Shankar, V.; Malmuth, N. D.

    1979-01-01

    A computational model for the flow field of three dimensional incompressible wall jets prototypic of thrust augmenting ejectors with large cross flow is presented. The formulation employs boundary layer equations in an orthogonal curvilinear coordinate system. Simulation of laminar as well as turbulen wall jets is reported. Quantification of jet spreading, jet growth, nominal separation, and jet shrink effects due to corss flow are discussed.

  14. Dahl SS rats demonstrate enhanced aortic perivascular adipose tissue-mediated buffering of vasoconstriction through activation of NOS in the endothelium

    PubMed Central

    Spradley, Frank T.; Ho, Dao H.

    2015-01-01

    Perivascular adipose tissue (PVAT) mediates buffering of vasoconstriction through activation of endothelium-derived factors. We hypothesized that the PVAT of Dahl salt-sensitive (Dahl SS) rats has reduced ability to buffer vasoconstriction. Vascular reactivity experiments were performed on aortic rings with PVAT intact (+PVAT) or removed (−PVAT), and endothelium intact (+ENDO) or removed (−ENDO) from Dahl SS rats and control SS.13BN rats (Dahl SS rats that have had chromosome 13 completely replaced with that of the Brown Norway rat, rendering this strain insensitive to high-salt or high-fat diet-induced hypertension). Endothelial dysfunction, assessed by ACh-mediated vasorelaxation, was confirmed in aortic rings of Dahl SS rats. The +PVAT+ENDO aortic rings had indistinguishable phenylephrine-induced vasoconstriction between genotypes. In both strains, removal of PVAT significantly enhanced vasoconstriction. Dahl SS rat −PVAT+ENDO aortic rings displayed exaggerated vasoconstriction to phenylephrine vs. SS.13BN rats, indicating that PVAT-mediated buffering of vasoconstriction was greater in Dahl SS rats. Removal of both the ENDO and PVAT restored vasoconstriction in both strains. The nitric oxide synthase (NOS) inhibitor, Nω-nitro-l-arginine methyl ester (l-NAME), produced a similar effect as that seen with −ENDO. These data indicate that the function of the PVAT to activate endothelium-derived NOS is enhanced in Dahl SS compared with SS.13BN rats and, most likely, occurs through a pathway that is distinct from ACh-mediated activation of NOS. PVAT weight and total PVAT leptin levels were greater in Dahl SS rats. Leptin induced a significantly decreased vasoconstriction in −PVAT+ENDO aortic rings from Dahl SS rats, but not SS.13BN rats. In contrast to our initial hypothesis, PVAT in Dahl SS rats buffers vasoconstriction by activating endothelial NOS via mechanisms that may include the involvement of leptin. Thus, the PVAT serves a vasoprotective role in

  15. Skipping Strategy (SS) for Initial Population of Job-Shop Scheduling Problem

    NASA Astrophysics Data System (ADS)

    Abdolrazzagh-Nezhad, M.; Nababan, E. B.; Sarim, H. M.

    2018-03-01

    Initial population in job-shop scheduling problem (JSSP) is an essential step to obtain near optimal solution. Techniques used to solve JSSP are computationally demanding. Skipping strategy (SS) is employed to acquire initial population after sequence of job on machine and sequence of operations (expressed in Plates-jobs and mPlates-jobs) are determined. The proposed technique is applied to benchmark datasets and the results are compared to that of other initialization techniques. It is shown that the initial population obtained from the SS approach could generate optimal solution.

  16. NARSTO EPA SS LOS ANGELES PM25 NITRATE

    Atmospheric Science Data Center

    2018-04-09

    NARSTO EPA SS LOS ANGELES PM25 NITRATE Project Title:  NARSTO Discipline:  ... Order:   E arthdata Search Parameters:  Nitrate Particles Order Data:  Earthdata Search:   Order ... Guide Documents:  Los Angeles PM25 Nitrate Guide Los Angeles Project Plan  (PDF) Los ...

  17. The jets of AGN as giant coaxial cables

    NASA Astrophysics Data System (ADS)

    Gabuzda, Denise C.; Nagle, Matt; Roche, Naomi

    2018-04-01

    Context. The currents carried by the jets of active galactic nuclei (AGNs) can be probed using maps of the Faraday rotation measure (RM), since a jet current will be accompanied by a toroidal magnetic field, which will give rise to a systematic change in the RM across the jet. Aims: The aim of this study is to identify new AGNs displaying statistically significant transverse RM gradients across their parsec-scale jets, in order to determine how often helical magnetic fields occur in AGN jets, and to look for overall patterns in the implied directions for the toroidal field components and jet currents. Methods: We have carried out new analyses of Faraday RM maps derived from previously published 8.1, 8.4, 12.1 and 15.3 GHz data obtained in 2006 on the NRAO Very Long Baseline Array (VLBA). In a number of key ways, our procedures were identical to those of the original authors, but the new imaging and analysis differs from the original methods in several ways: the technique used to match the resolutions at the different frequencies, limits on the widths spanned by the RM gradients analyzed, treatment of core-region RM gradients, approach to estimation of the significances of the gradients analyzed, and inclusion of a supplementary analysis using circular beams with areas equal to those of the corresponding elliptical naturally weighted beams. Results: This new analysis has substantially increased the number of AGNs known to display transverse RM gradients that may reflect the presence of a toroidal magnetic-field component. The collected data on parsec and kiloparsec scales indicate that the current typically flows inward along the jet axis and outward in a more extended region surrounding the jet, typical to the current structure of a co-axial cable, accompanied by a self-consistent system of nested helical magnetic fields, whose toroidal components give rise to the observed transverse Faraday rotation gradients. Conclusions: The new results presented here make it

  18. AC electrified jets in a flow-focusing device: Jet length scaling

    PubMed Central

    García-Sánchez, Pablo; Alzaga-Gimeno, Javier; Baret, Jean-Christophe

    2016-01-01

    We use a microfluidic flow-focusing device with integrated electrodes for controlling the production of water-in-oil drops. In a previous work, we reported that very long jets can be formed upon application of AC fields. We now study in detail the appearance of the long jets as a function of the electrical parameters, i.e., water conductivity, signal frequency, and voltage amplitude. For intermediate frequencies, we find a threshold voltage above which the jet length rapidly increases. Interestingly, this abrupt transition vanishes for high frequencies of the signal and the jet length grows smoothly with voltage. For frequencies below a threshold value, we previously reported a transition from a well-behaved uniform jet to highly unstable liquid structures in which axisymmetry is lost rather abruptly. These liquid filaments eventually break into droplets of different sizes. In this work, we characterize this transition with a diagram as a function of voltage and liquid conductivity. The electrical response of the long jets was studied via a distributed element circuit model. The model allows us to estimate the electric potential at the tip of the jet revealing that, for any combination of the electrical parameters, the breakup of the jet occurs at a critical value of this potential. We show that this voltage is around 550 V for our device geometry and choice of flow rates. PMID:27375826

  19. AC electrified jets in a flow-focusing device: Jet length scaling.

    PubMed

    Castro-Hernández, Elena; García-Sánchez, Pablo; Alzaga-Gimeno, Javier; Tan, Say Hwa; Baret, Jean-Christophe; Ramos, Antonio

    2016-07-01

    We use a microfluidic flow-focusing device with integrated electrodes for controlling the production of water-in-oil drops. In a previous work, we reported that very long jets can be formed upon application of AC fields. We now study in detail the appearance of the long jets as a function of the electrical parameters, i.e., water conductivity, signal frequency, and voltage amplitude. For intermediate frequencies, we find a threshold voltage above which the jet length rapidly increases. Interestingly, this abrupt transition vanishes for high frequencies of the signal and the jet length grows smoothly with voltage. For frequencies below a threshold value, we previously reported a transition from a well-behaved uniform jet to highly unstable liquid structures in which axisymmetry is lost rather abruptly. These liquid filaments eventually break into droplets of different sizes. In this work, we characterize this transition with a diagram as a function of voltage and liquid conductivity. The electrical response of the long jets was studied via a distributed element circuit model. The model allows us to estimate the electric potential at the tip of the jet revealing that, for any combination of the electrical parameters, the breakup of the jet occurs at a critical value of this potential. We show that this voltage is around 550 V for our device geometry and choice of flow rates.

  20. ATLAS jet trigger update for the LHC run II

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Delgado, A. T.

    The CERN Large Hadron Collider is the biggest and most powerful particle collider ever built. It produces up to 40 million proton-proton collisions per second at unprecedented energies to explore the fundamental laws and properties of Nature. The ATLAS experiment is one of the detectors that analyses and records these collisions. It generates dozens of GB/s of data that has to be reduced before it can be permanently stored, the event selection is made by the ATLAS trigger system, which reduces the data volume by a factor of 105. The trigger system has to be highly configurable in order tomore » adapt to changing running conditions and maximize the physics output whilst keeping the output rate under control. A particularly interesting pattern generated during collisions consists of a collimated spray of particles, known as a hadronic jet. To retain the interesting jets and efficiently reject the overwhelming background, optimal jet energy resolution is needed. Therefore the Jet trigger software requires CPU-intensive reconstruction algorithms. In order to reduce the resources needed for the reconstruction step, a partial detector readout scheme was developed, which effectively suppresses the low activity regions of the calorimeter. In this paper we describe the overall ATLAS trigger software, and the jet trigger in particular, along with the improvements made on the system. We then focus on detailed studies of the algorithm timing and the performance impact of the full and partial calorimeter readout schemes. We conclude with an outlook of the jet trigger plans for the next LHC data-taking period. (authors)« less

  1. Proton transfer and hydrogen bonding in the organic solid state: a combined XRD/XPS/ssNMR study of 17 organic acid-base complexes.

    PubMed

    Stevens, Joanna S; Byard, Stephen J; Seaton, Colin C; Sadiq, Ghazala; Davey, Roger J; Schroeder, Sven L M

    2014-01-21

    The properties of nitrogen centres acting either as hydrogen-bond or Brønsted acceptors in solid molecular acid-base complexes have been probed by N 1s X-ray photoelectron spectroscopy (XPS) as well as (15)N solid-state nuclear magnetic resonance (ssNMR) spectroscopy and are interpreted with reference to local crystallographic structure information provided by X-ray diffraction (XRD). We have previously shown that the strong chemical shift of the N 1s binding energy associated with the protonation of nitrogen centres unequivocally distinguishes protonated (salt) from hydrogen-bonded (co-crystal) nitrogen species. This result is further supported by significant ssNMR shifts to low frequency, which occur with proton transfer from the acid to the base component. Generally, only minor chemical shifts occur upon co-crystal formation, unless a strong hydrogen bond is formed. CASTEP density functional theory (DFT) calculations of (15)N ssNMR isotropic chemical shifts correlate well with the experimental data, confirming that computational predictions of H-bond strengths and associated ssNMR chemical shifts allow the identification of salt and co-crystal structures (NMR crystallography). The excellent agreement between the conclusions drawn by XPS and the combined CASTEP/ssNMR investigations opens up a reliable avenue for local structure characterization in molecular systems even in the absence of crystal structure information, for example for non-crystalline or amorphous matter. The range of 17 different systems investigated in this study demonstrates the generic nature of this approach, which will be applicable to many other molecular materials in organic, physical, and materials chemistry.

  2. The SS x-ray unit as an instrument for "total registration" and "race selection".

    PubMed

    Schmidt, Mathias; Winzen, Tina; Gross, Dominik

    2015-05-01

    The aim of this article is to show that, after the onset of World War II at the latest, the central task of the x-ray unit of the Nazi-SS (Schutzstaffel) led by Prof. Hans Holfelder was by no means the early diagnosis of tuberculosis. Its primary purpose, rather, was to serve the various "racial" and inhuman aims of the SS itself. Main historical sources and information about the SS x-ray unit are surveyed and analyzed. Clearly, the significance of the x-ray storm unit was increasingly subordinated to the necessities of the war until its original objectives disappeared from focus completely. The main purpose of operation of the x-ray storm unit thus by no means lay in the early detection of tuberculosis and did not therefore serve tuberculosis control. The actual objective lay, rather, in the implementation of SS aims in terms of Volk politics, genetics, and "racial hygiene".

  3. [Study on the fluctuation phenomena of arc plasma spraying jet].

    PubMed

    Zhao, Wen-hua; Liu, Di; Tian, Kuo

    2002-08-01

    The turbulence phenomenon is one of the most attractive characteristics of a DC arc plasma spraying jet. Most of the previous investigations believe that there is a laminar flow region in core of the jet. A spectrum diagnostic system has been built up in this paper to investigate these effects with the aid of high-speed digital camera. The FFT method has been applied to the analysis on the arc voltage and light signals. The influence of the arc behavior and the power supply on the jet is full-scale. It seems that there is not a laminar flow region in core of the jet. Moreover, from the light dynamic variation graph, the jet fluctuation due to the arc voltage behavior maybe is the dominant characteristic of the jet behavior.

  4. Jet Mixing in a Reacting Cylindrical Crossflow

    NASA Technical Reports Server (NTRS)

    Leong, M. Y.; Samuelsen, G. S.; Holdeman, J. D.

    1995-01-01

    This paper addresses the mixing of air jets into the hot, fuel-rich products of a gas turbine primary zone. The mixing, as a result, occurs in a reacting environment with chemical conversion and substantial heat release. The geometry is a crossflow confined in a cylindrical duct with side-wall injection of jets issuing from round orifices. A specially designed reactor, operating on propane, presents a uniform mixture without swirl to mixing modules consisting of 8, 9, 10, and 12 holes at a momentum-flux ratio of 57 and a jet-to-mainstream mass-flow ratio of 2.5. Concentrations of O2, CO2, CO, and HC are obtained upstream, downstream, and within the orifice plane. O2 profiles indicate jet penetration while CO2, CO, and HC profiles depict the extent of reaction. Jet penetration is observed to be a function of the number of orifices and is found to affect the mixing in the reacting system. The results demonstrate that one module (the 12-hole) produces near-optimal penetration defined here as a jet penetration closest to the module half-radius, and hence the best uniform mixture at a plane one duct radius from the orifice leading edge.

  5. Dynamical Evolution of the Recent Jet in CH Cyg

    NASA Astrophysics Data System (ADS)

    Karovska, Margarita

    2011-10-01

    We propose to carry out Chandra ACIS-S observations combined with HST/WFC3multi-wavelength imaging of the powerful, multi-component jet which was detectedin 2008 in the nearby symbiotic CH Cyg. CH Cyg is a fascinating system containing an evolved giant and a wind-accreting white dwarf, and it is one of the few symbiotics showing jet activity, especially in X-rays. Our goal is to measure the physical characteristics of the individual jet components, from the central source to the region of interaction with the circumbinary environment, reaching to within a few AU from the source of the jet. We will determine the characteristics of the central source, and of the inner and the outer jet, and the dynamical evolution, including precession, and kinematics of the ejecta.

  6. Dynamical Evolution of the Recent Jet in CH Cyg

    NASA Astrophysics Data System (ADS)

    Karovska, Margarita

    2011-09-01

    We propose to carry out Chandra ACIS-S observations combined with HST/WFC3 multi-wavelength imaging of the powerful, multi-component jet which was detected in 2008 in the nearby symbiotic CH Cyg. CH Cyg is a fascinating system containing an evolved giant and a wind-accreting white dwarf, and it is one of the few symbiotics showing jet activity, especially in X-rays. Our goal is to measure the physical characteristics of the individual jet components, from the central source to the region of interaction with the circumbinary environment, reaching to within a few AU from the source of the jet. We will determine the characteristics of the central source, and of the inner and the outer jet, and the dynamical evolution, including precession, and kinematics of the ejecta.

  7. Simulation of Sweep-Jet Flow Control, Single Jet and Full Vertical Tail

    NASA Technical Reports Server (NTRS)

    Childs, Robert E.; Stremel, Paul M.; Garcia, Joseph A.; Heineck, James T.; Kushner, Laura K.; Storms, Bruce L.

    2016-01-01

    This work is a simulation technology demonstrator, of sweep jet flow control used to suppress boundary layer separation and increase the maximum achievable load coefficients. A sweep jet is a discrete Coanda jet that oscillates in the plane parallel to an aerodynamic surface. It injects mass and momentum in the approximate streamwise direction. It also generates turbulent eddies at the oscillation frequency, which are typically large relative to the scales of boundary layer turbulence, and which augment mixing across the boundary layer to attack flow separation. Simulations of a fluidic oscillator, the sweep jet emerging from a nozzle downstream of the oscillator, and an array of sweep jets which suppresses boundary layer separation are performed. Simulation results are compared to data from a dedicated validation experiment of a single oscillator and its sweep jet, and from a wind tunnel test of a full-scale Boeing 757 vertical tail augmented with an array of sweep jets. A critical step in the work is the development of realistic time-dependent sweep jet inflow boundary conditions, derived from the results of the single-oscillator simulations, which create the sweep jets in the full-tail simulations. Simulations were performed using the computational fluid dynamics (CFD) solver Overow, with high-order spatial discretization and a range of turbulence modeling. Good results were obtained for all flows simulated, when suitable turbulence modeling was used.

  8. Sensitivity of jet substructure to jet-induced medium response

    NASA Astrophysics Data System (ADS)

    Milhano, Guilherme; Wiedemann, Urs Achim; Zapp, Korinna Christine

    2018-04-01

    Jet quenching in heavy ion collisions is expected to be accompanied by recoil effects, but unambiguous signals for the induced medium response have been difficult to identify so far. Here, we argue that modern jet substructure measurements can improve this situation qualitatively since they are sensitive to the momentum distribution inside the jet. We show that the groomed subjet shared momentum fraction zg, and the girth of leading and subleading subjets signal recoil effects with dependencies that are absent in a recoilless baseline. We find that recoil effects can explain most of the medium modifications to the zg distribution observed in data. Furthermore, for jets passing the Soft Drop Condition, recoil effects induce in the differential distribution of subjet separation ΔR12 a characteristic increase with ΔR12, and they introduce a characteristic enhancement of the girth of the subleading subjet with decreasing zg. We explain why these qualitatively novel features, that we establish in JEWEL+PYTHIA simulations, reflect generic physical properties of recoil effects that should therefore be searched for as telltale signatures of jet-induced medium response.

  9. Thick SS316 materials TIG welding development activities towards advanced fusion reactor vacuum vessel applications

    NASA Astrophysics Data System (ADS)

    Kumar, B. Ramesh; Gangradey, R.

    2012-11-01

    Advanced fusion reactors like ITER and up coming Indian DEMO devices are having challenges in terms of their materials design and fabrication procedures. The operation of these devices is having various loads like structural, thermo-mechanical and neutron irradiation effects on major systems like vacuum vessel, divertor, magnets and blanket modules. The concept of double wall vacuum vessel (VV) is proposed in view of protecting of major reactor subsystems like super conducting magnets, diagnostic systems and other critical components from high energy 14 MeV neutrons generated from fusion plasma produced by D-T reactions. The double walled vacuum vessel is used in combination with pressurized water circulation and some special grade borated steel blocks to shield these high energy neutrons effectively. The fabrication of sub components in VV are mainly used with high thickness SS materials in range of 20 mm- 60 mm of various grades based on the required protocols. The structural components of double wall vacuum vessel uses various parts like shields, ribs, shells and diagnostic vacuum ports. These components are to be developed with various welding techniques like TIG welding, Narrow gap TIG welding, Laser welding, Hybrid TIG laser welding, Electron beam welding based on requirement. In the present paper the samples of 20 mm and 40 mm thick SS 316 materials are developed with TIG welding process and their mechanical properties characterization with Tensile, Bend tests and Impact tests are carried out. In addition Vickers hardness tests and microstructural properties of Base metal, Heat Affected Zone (HAZ) and Weld Zone are done. TIG welding application with high thick SS materials in connection with vacuum vessel requirements and involved criticalities towards welding process are highlighted.

  10. Search for Doppler-shifted gamma-ray emission from SS 433 using the SMM spectrometer

    NASA Technical Reports Server (NTRS)

    Geldzahler, B. J.; Share, G. H.; Kinzer, R. L.; Magura, J.; Chupp, E. L.

    1989-01-01

    Data accumulated from 1980 to 1983 with the Gamma Ray Spectrometer aboard NASA's Solar Maximum Mission (SMM) satellite were searched for evidence of red and blue Doppler-shifted 1.37 MeV Mg-24 nuclear lines from SS 433. The SMM data base covers 270 days when SS 433 was in the field of view and includes periods of radio flaring and quiescence. No evidence was found for Doppler-shifted line emission in any of the spectra. The range of 3-sigma upper limits for individual 9 day integration periods was 0.0008-0.0023 photons/sq cm per sec for the blue beam, encompassing the reported about 1.5 MeV line, and 0.0008-0.002 photons/sq cm per sec for the red beam, encompassing the reported about 1.2 MeV line; the average 3-sigma upper limit in each beam for shifted about 1.37 MeV lines is 0.0015 photons/sq cm per sec for single 9 day integrations. The 3-sigma upper limit on 1.37 MeV gamma-ray emission over 23 9-day integration intervals for the red beam and 28 intervals for the blue beam is 0.0002 photons/sq cm per sec. These new limits from SMM can be reconciled with the HEAO 3 results only if SS 433 emits gamma radiation at or above the SMM sensitivity limit on rare occasions due to variable physical conditions in the system.

  11. CENTIMETER CONTINUUM OBSERVATIONS OF THE NORTHERN HEAD OF THE HH 80/81/80N JET: REVISING THE ACTUAL DIMENSIONS OF A PARSEC-SCALE JET

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Masque, Josep M.; Estalella, Robert; Girart, Josep M.

    2012-10-10

    We present 6 and 20 cm Jansky Very Large Array/Very Large Array observations of the northern head of the HH 80/81/80N jet, one of the largest collimated jet systems known so far, aimed to look for knots farther than HH 80N, the northern head of the jet. Aligned with the jet and 10' northeast of HH 80N, we found a radio source not reported before, with a negative spectral index similar to that of HH 80, HH 81, and HH 80N. The fit of a precessing jet model to the knots of the HH 80/81/80N jet, including the new source,more » shows that the position of this source is close to the jet path resulting from the modeling. If the new source belongs to the HH 80/81/80N jet, its derived size and dynamical age are 18.4 pc and >9 Multiplication-Sign 10{sup 3} yr, respectively. If the jet is symmetric, its southern lobe would expand beyond the cloud edge resulting in an asymmetric appearance of the jet. Based on the updated dynamical age, we speculate on the possibility that the HH 80/81/80N jet triggered the star formation observed in a dense core found ahead of HH 80N, which shows signposts of interaction with the jet. These results indicate that parsec-scale radio jets can play a role in the stability of dense clumps and the regulation of star formation in the molecular cloud.« less

  12. Re-Educating Jet-Engine-Researchers to Stay Relevant

    NASA Astrophysics Data System (ADS)

    Gal-Or, Benjamin

    2016-06-01

    To stay relevantly supported, jet-engine researchers, designers and operators should follow changing uses of small and large jet engines, especially those anticipated to be used by/in the next generation, JET-ENGINE-STEERED ("JES") fleets of jet drones but fewer, JES-Stealth-Fighter/Strike Aircraft. In addition, some diminishing returns from isolated, non-integrating, jet-engine component studies, vs. relevant, supersonic, shock waves control in fluidic-JES-side-effects on compressor stall dynamics within Integrated Propulsion Flight Control ("IPFC"), and/or mechanical JES, constitute key relevant methods that currently move to China, India, South Korea and Japan. The central roles of the jet engine as primary or backup flight controller also constitute key relevant issues, especially under post stall conditions involving induced engine-stress while participating in crash prevention or minimal path-time maneuvers to target. And when proper instructors are absent, self-study of the JES-STVS REVOLUTION is an updating must, where STVS stands for wing-engine-airframe-integrated, embedded stealthy-jet-engine-inlets, restructured engines inside Stealth, Tailless, canard-less, Thrust Vectoring IFPC Systems. Anti-terror and Airliners Super-Flight-Safety are anticipated to overcome US legislation red-tape that obstructs JES-add-on-emergency-kits-use.

  13. Enhanced visible and near-infrared capabilities of the JET mirror-linked divertor spectroscopy system

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lomanowski, B. A., E-mail: b.a.lomanowski@durham.ac.uk; Sharples, R. M.; Meigs, A. G.

    2014-11-15

    The mirror-linked divertor spectroscopy diagnostic on JET has been upgraded with a new visible and near-infrared grating and filtered spectroscopy system. New capabilities include extended near-infrared coverage up to 1875 nm, capturing the hydrogen Paschen series, as well as a 2 kHz frame rate filtered imaging camera system for fast measurements of impurity (Be II) and deuterium Dα, Dβ, Dγ line emission in the outer divertor. The expanded system provides unique capabilities for studying spatially resolved divertor plasma dynamics at near-ELM resolved timescales as well as a test bed for feasibility assessment of near-infrared spectroscopy.

  14. Evidence for two distinct KiSS genes in non-placental vertebrates that encode kisspeptins with different gonadotropin-releasing activities in fish and mammals.

    PubMed

    Felip, Alicia; Zanuy, Silvia; Pineda, Rafael; Pinilla, Leonor; Carrillo, Manuel; Tena-Sempere, Manuel; Gómez, Ana

    2009-11-27

    Kisspeptins, the products of KiSS-1 gene, have recently emerged as fundamental regulators of reproductive function in different mammalian and, presumably, non-mammalian species. To date, a single form of KiSS-1 has been described in mammals, and recently, in several fish species and Xenopus. We report herein the cloning and characterization of two distinct KiSS-like genes, namely, KiSS-1 and KiSS-2, in the teleost sea bass. While KiSS-1 encodes a peptide identical to rodent kisspeptin-10, the predicted KiSS-2 decapeptide diverges at 4 amino acids (FNFNPFGLRF). Genome database searches showed that both genes are present in non-placental vertebrate genomes. Indeed, phylogenetic and genome mapping analyses suggest that KiSS-1 and KiSS-2 are paralogous genes that originated by duplication of an ancestral gene, although KiSS-2 is lost in placental mammals. KiSS-1 and KiSS-2 mRNAs are present in brain and gonads of sea bass, medaka and zebrafish. Comparative functional studies demonstrated that KiSS-2 decapeptide was significantly more potent than KiSS-1 peptide in inducing LH and FSH secretion in sea bass. In contrast, KiSS-2 decapeptide only weakly elicited LH secretion in rats, whereas KiSS-1 peptide was maximally effective. Our data are the first to provide conclusive evidence for the existence of a second KiSS gene, KiSS-2, in non-placental vertebrates, whose product is likely to play a dominant stimulatory role in the regulation of the gonadotropic axis at least in teleosts.

  15. Accommodation of practical constraints by a linear programming jet select. [for Space Shuttle

    NASA Technical Reports Server (NTRS)

    Bergmann, E.; Weiler, P.

    1983-01-01

    An experimental spacecraft control system will be incorporated into the Space Shuttle flight software and exercised during a forthcoming mission to evaluate its performance and handling qualities. The control system incorporates a 'phase space' control law to generate rate change requests and a linear programming jet select to compute jet firings. Posed as a linear programming problem, jet selection must represent the rate change request as a linear combination of jet acceleration vectors where the coefficients are the jet firing times, while minimizing the fuel expended in satisfying that request. This problem is solved in real time using a revised Simplex algorithm. In order to implement the jet selection algorithm in the Shuttle flight control computer, it was modified to accommodate certain practical features of the Shuttle such as limited computer throughput, lengthy firing times, and a large number of control jets. To the authors' knowledge, this is the first such application of linear programming. It was made possible by careful consideration of the jet selection problem in terms of the properties of linear programming and the Simplex algorithm. These modifications to the jet select algorithm may by useful for the design of reaction controlled spacecraft.

  16. Observations of breakup processes of liquid jets using real-time X-ray radiography

    NASA Technical Reports Server (NTRS)

    Char, J. M.; Kuo, K. K.; Hsieh, K. C.

    1988-01-01

    To unravel the liquid-jet breakup process in the nondilute region, a newly developed system of real-time X-ray radiography, an advanced digital image processor, and a high-speed video camera were used. Based upon recorded X-ray images, the inner structure of a liquid jet during breakup was observed. The jet divergence angle, jet breakup length, and fraction distributions along the axial and transverse directions of the liquid jets were determined in the near-injector region. Both wall- and free-jet tests were conducted to study the effect of wall friction on the jet breakup process.

  17. Multi-Stream Saline-Jet Dissection Using a Simple Irrigation System Defines Difficult Tissue Planes

    PubMed Central

    Ng, Philip CH

    2010-01-01

    Introduction: Single-stream hydro-jet dissection is increasingly used in various laparoscopic procedures, but its use requires special equipment. We describe a simple method for using an irrigation system for saline-jet tissue dissection as a useful adjunct prior to adhesiolysis. Material and Methods: Intraabdominal adhesions prolong laparoscopic procedures, because tissue planes are difficult to identify. We performed multi-jet saline dissection (MSSJ) between 2000 and 2009 in more than 500 patients during laparoscopy involving hernias, gallbladders, appendices, and intestinal obstructions. We use a standard suction irrigation probe, which is attached to a 1-liter saline bag with an inflatable cuff around to create a pressure of 250mm Hg to 300mm Hg. In effect, this is the standard setup generally used for irrigation. After using saline dissection, tissue planes can be better defined and the structures can then be separated. Result and Discussion: Using this method, we have successfully identified tissue planes in spite of dense adhesions, and our conversion rates to open have been reduced dramatically. This method is relatively safer than other modalities of tissue dissection, such as diathermy, ultrasonic, blunt or sharp dissection. The disadvantage is that with tissues saturated with saline it becomes more difficult to use diathermy hemostasis. Care has to be exercised in monitoring the temperature and volume of the fluid used. PMID:20529528

  18. The Outer X-ray and Radio Jets in R Aquarii

    NASA Technical Reports Server (NTRS)

    Kellogg, E.; Anderson, C.; DePasquale, J.; Korreck, K.; Nichols, J.; Sokoloski, J.; Krauss, M.; Pedelty, J.

    2007-01-01

    The symbiotic star R Aquarii has been known to emit collimated outflow in the form of jets for many years. We report on five years of observations in x-rays and radio using Chandra, VLA and XMM-Newton. We discuss the evolution of the outer thermal jets, including new observations performed in June and October 2005. We see motion of the NE x-ray jet at a projected velocity of about 600 km (sup -1). The SW x-ray jet has almost disappeared between 2000.7 and 2004.0. An XMM grating spectrum of the NE jet confirms the existence of O VII He-like lines, and offers the possibility of doing plasma density diagnostics. We comment on on the physics of cooling in the SW jet and implications for the density of the x-ray emitting gas, the heating mechanism, and mass and kinetic energy in the jets and its implications for the system as a whole. This work was supported by NASA and NSF.

  19. Numerical evaluation of single central jet for turbine disk cooling

    NASA Astrophysics Data System (ADS)

    Subbaraman, M. R.; Hadid, A. H.; McConnaughey, P. K.

    The cooling arrangement of the Space Shuttle Main Engine High Pressure Oxidizer Turbopump (HPOTP) incorporates two jet rings, each of which produces 19 high-velocity coolant jets. At some operating conditions, the frequency of excitation associated with the 19 jets coincides with the natural frequency of the turbine blades, contributing to fatigue cracking of blade shanks. In this paper, an alternate turbine disk cooling arrangement, applicable to disk faces of zero hub radius, is evaluated, which consists of a single coolant jet impinging at the center of the turbine disk. Results of the CFD analysis show that replacing the jet ring with a single central coolant jet in the HPOTP leads to an acceptable thermal environment at the disk rim. Based on the predictions of flow and temperature fields for operating conditions, the single central jet cooling system was recommended for implementation into the development program of the Technology Test Bed Engine at NASA Marshall Space Flight Center.

  20. Subacute effects of inhaled Jet Fuel-A (Jet A) on airway and immune function in female rats.

    PubMed

    Sweeney, Lisa M; Prues, Susan L; Reboulet, James E

    2013-04-01

    Two studies were conducted to assess the potential airway and immune effects following subacute (14 d) exposure of female rats to 500, 1000 or 2000 mg/m³ of Jet-A for 4 h/d. The first study used Sprague-Dawley rats; the second study included both Fischer 344 (F344) and Sprague-Dawley rats. In the first study, exposure to 2000 mg/m³ jet fuel may have caused significant upper airway inflammation on day 7 post-exposure, as indicated by elevated protein and lactate dehydrogenase in nasal lavage fluid, but any inflammation resolved by day 14 post-exposure. No significant impact on immune cell populations in the spleens was observed. The histological examination showed no evidence of infectious or toxic effect. In the second study, body weights of the F344 rats in the 2000 mg/m³ group were depressed, as compared to the controls, at the end of the exposure. Some lung lavage fluid markers were increased at 24 h after the final exposure, however, no test article-induced histological changes were observed in the lungs, nasal cavities, or any other tissue of any of the jet fuel exposed animals. Overall, these studies demonstrated limited evidence of effects of 14 d of exposure to Jet A on the airways, immune system, or any other organ or system of female Sprague-Dawley and F344 rats, with no remarkable differences between strains. The lack of identified significant airway or immune effects was in contrast to previous examinations of jet fuel for pulmonary toxicity in mice and rats and for immunotoxicity in mice.

  1. Characteristics of transverse hydrogen jet in presence of multi air jets within scramjet combustor

    NASA Astrophysics Data System (ADS)

    Barzegar Gerdroodbary, M.; Fallah, Keivan; Pourmirzaagha, H.

    2017-03-01

    In this article, three-dimensional simulation is performed to investigate the effects of micro air jets on mixing performances of cascaded hydrogen jets within a scramjet combustor. In order to compare the efficiency of this technique, constant total fuel rate is injected through one, four, eight and sixteen arrays of portholes in a Mach 4.0 crossflow with a fuel global equivalence ratio of 0.5. In this method, micro air jets are released within fuel portholes to augment the penetration in upward direction. Extensive studies were performed by using the Reynolds-averaged Navier-Stokes equations with Menter's Shear Stress Transport (SST) turbulence model. Numerical studies on various air and fuel arrangements are done and the mixing rate and penetration are comprehensively investigated. Also, the flow feature of the fuel and air jets for different configuration is revealed. According to the obtained results, the influence of the micro air jets is significant and the presence of micro air jets increases the mixing rate about 116%, 77%, 56% and 41% for single, 4, 8 and 16 multi fuel jets, respectively. The maximum mixing rate of the hydrogen jet is obtained when the air jets are injected within the sixteen multi fuel jets. According to the circulation analysis of the flow for different air and fuel arrangements, it was found that the effects of air jets on flow structure are varied in various conditions and the presence of the micro jet highly intensifies the circulation in the case of 8 and 16 multi fuel jets.

  2. The remarkable AGN jets

    NASA Astrophysics Data System (ADS)

    Komissarov, Serguei

    The jets from active galactic nuclei exhibit stability which seems to be far superior compared to that of terrestrial and laboratory jets. They manage to propagate over distances up to a billion of initial jet radii. Yet this may not be an indication of some exotic physics but mainly a reflection of the specific environment these jets propagate through. The key property of this environment is a rapid decline of density and pressure along the jet, which promotes its rapid expansion. Such an expansion can suppress global instabilities, which require communication across the jet, and hence ensure its survival over huge distances. At kpc scales, some AGN jets do show signs of strong instabilities and even turn into plumes. This could be a result of the flattening of the external pressure distribution in their host galaxies or inside the radio lobes. In this regard, we discuss the possible connection between the stability issue and the Fanaroff-Riley classification of extragalactic radio sources. The observations of AGN jets on sub-kpc scale do not seem to support their supposed lack of causal connectivity. When interpreted using simple kinematic models, they reveal a rather perplexing picture with more questions than answers on the jets dynamics.

  3. ASCA observations of SS Cygni during an anomalous outburst

    NASA Technical Reports Server (NTRS)

    Nousek, John A.; Baluta, Christopher J.; Corbet, Robin H. D.; Mukai, Koji; Osborne, Julian P.; Ishida, Manabu

    1994-01-01

    SS Cygni was observed by the ASCA satellite on 1993 May 27, the first cataclysmic variable studied by ASCA. The observations were conducted while the system was in an outburst of the 'anomalous' variety. The SIS spectrum cannot be explained by two-temperature Raymond-Smith coronal plasma models as invoked in previous studies with lower spectral resolution. Significantly better agreement is found for models with plasma emission at kT = 0.8, 3.5 keV and thermal bremsstrahlung at kT = 18 keV. The gas imaging spectrometer (GIS) data are consistent with the solid state imaging spectrometer (SIS) data, showing evidence for Fe line emission but showing no evidence of pulsation over times ranging from seconds to minutes. These observations seem at variance with standard theory in two regards: we simultaneously see hard X-rays and optically thin soft X-rays while the system is in outburst, and we see a nonsmooth emission measure distribution. We speculate on possible scenarios which might resolve these differences.

  4. The Phage Lysin PlySs2 Decolonizes Streptococcus suis from Murine Intranasal Mucosa.

    PubMed

    Gilmer, Daniel B; Schmitz, Jonathan E; Thandar, Mya; Euler, Chad W; Fischetti, Vincent A

    2017-01-01

    Streptococcus suis infects pigs worldwide and may be zoonotically transmitted to humans with a mortality rate of up to 20%. S. suis has been shown to develop in vitro resistance to the two leading drugs of choice, penicillin and gentamicin. Because of this, we have pursued an alternative therapy to treat these pathogens using bacteriophage lysins. The bacteriophage lysin PlySs2 is derived from an S. suis phage and displays potent lytic activity against most strains of that species including serotypes 2 and 9. At 64 μg/ml, PlySs2 reduced multiple serotypes of S. suis by 5 to 6-logs within 1 hour in vitro and exhibited a minimum inhibitory concentration (MIC) of 32 μg/ml for a S. suis serotype 2 strain and 64 μg/ml for a serotype 9 strain. Using a single 0.1-mg dose, the colonizing S. suis serotype 9 strain was reduced from the murine intranasal mucosa by >4 logs; a 0.1-mg dose of gentamicin reduced S. suis by <3-logs. A combination of 0.05 mg PlySs2 + 0.05 mg gentamicin reduced S. suis by >5-logs. While resistance to gentamicin was induced after systematically increasing levels of gentamicin in an S. suis culture, the same protocol resulted in no observable resistance to PlySs2. Thus, PlySs2 has both broad and high killing activity against multiple serotypes and strains of S. suis, making it a possible tool in the control and prevention of S. suis infections in pigs and humans.

  5. The Phage Lysin PlySs2 Decolonizes Streptococcus suis from Murine Intranasal Mucosa

    PubMed Central

    Gilmer, Daniel B.; Schmitz, Jonathan E.; Thandar, Mya; Euler, Chad W.; Fischetti, Vincent A.

    2017-01-01

    Streptococcus suis infects pigs worldwide and may be zoonotically transmitted to humans with a mortality rate of up to 20%. S. suis has been shown to develop in vitro resistance to the two leading drugs of choice, penicillin and gentamicin. Because of this, we have pursued an alternative therapy to treat these pathogens using bacteriophage lysins. The bacteriophage lysin PlySs2 is derived from an S. suis phage and displays potent lytic activity against most strains of that species including serotypes 2 and 9. At 64 μg/ml, PlySs2 reduced multiple serotypes of S. suis by 5 to 6-logs within 1 hour in vitro and exhibited a minimum inhibitory concentration (MIC) of 32 μg/ml for a S. suis serotype 2 strain and 64 μg/ml for a serotype 9 strain. Using a single 0.1-mg dose, the colonizing S. suis serotype 9 strain was reduced from the murine intranasal mucosa by >4 logs; a 0.1-mg dose of gentamicin reduced S. suis by <3-logs. A combination of 0.05 mg PlySs2 + 0.05 mg gentamicin reduced S. suis by >5-logs. While resistance to gentamicin was induced after systematically increasing levels of gentamicin in an S. suis culture, the same protocol resulted in no observable resistance to PlySs2. Thus, PlySs2 has both broad and high killing activity against multiple serotypes and strains of S. suis, making it a possible tool in the control and prevention of S. suis infections in pigs and humans. PMID:28046082

  6. HIV-Derived ssRNA Binds to TLR8 to Induce Inflammation-Driven Macrophage Foam Cell Formation

    PubMed Central

    Bernard, Mark A.; Han, Xinbing; Inderbitzin, Sonya; Agbim, Ifunanya; Zhao, Hui; Koziel, Henry; Tachado, Souvenir D.

    2014-01-01

    Even though combined anti-retroviral therapy (cART) dramatically improves patient survival, they remain at a higher risk of being afflicted with non-infectious complications such as cardiovascular disease (CVD). This increased risk is linked to persistent inflammation and chronic immune activation. In this study, we assessed whether this complication is related to HIV-derived ssRNAs inducing in macrophages increases in TNFα release through TLR8 activation leading to foam cell formation. HIV ssRNAs induced foam cell formation in monocyte-derived macrophages (MDMs) in a dose-dependent manner. This response was reduced when either endocytosis or endosomal acidification was inhibited by dynasore or chloroquine, respectively. Using a flow cytometry FRET assay, we demonstrated that ssRNAs bind to TLR8 in HEK cells. In MDMs, ssRNAs triggered a TLR8-mediated inflammatory response that ultimately lead to foam cell formation. Targeted silencing of the TLR8 and MYD88 genes reduced foam cell formation. Furthermore, foam cell formation induced by these ssRNAs was blocked by an anti-TNFα neutralizing antibody. Taken together in MDMs, HIV ssRNAs are internalized; bind TLR8 in the endosome followed by endosomal acidification. TLR8 signaling then triggers TNFα release and ultimately leads to foam cell formation. As this response was inhibited by a blocking anti-TNFα antibody, drug targeting HIV ssRNA-driven TLR8 activation may serve as a potential therapeutic target to reduce chronic immune activation and inflammation leading to CVD in HIV+ patients. PMID:25090652

  7. Magnetosheath jets: MMS observations of internal structures and jet interactions with ambient plasma

    NASA Astrophysics Data System (ADS)

    Plaschke, F.; Karlsson, T.; Hietala, H.; Archer, M. O.; Voros, Z.; Nakamura, R.; Magnes, W.; Baumjohann, W.; Torbert, R. B.; Russell, C. T.; Giles, B. L.

    2017-12-01

    The dayside magnetosheath downstream of the quasi-parallel bow shock is commonly permeated by high-speed jets. Under low IMF cone angle conditions, large scale jets alone (with cross-sectional diameters of over 2 Earth radii) have been found to impact the subsolar magnetopause once every 6 minutes - smaller scale jets occurring much more frequently. The consequences of jet impacts on the magnetopause can be significant: they may trigger local reconnection and waves, alter radiation belt electron drift paths, disturb the geomagnetic field, and potentially generate diffuse throat aurora at the dayside ionosphere. Although some basic statistical properties of jets are well-established, their internal structure and interactions with the surrounding magnetosheath plasma are rather unknown. We present Magnetospheric Multiscale (MMS) observations which reveal a rich jet-internal structure of high-amplitude plasma moment and magnetic field variations and associated currents. These variations/structures are generally found to be in thermal and magnetic pressure balance; they mostly (but not always) convect with the plasma flow. Small velocity differences between plasma and structures are revealed via four-spacecraft timing analysis. Inside a jet core region, where the plasma velocity maximizes, structures are found to propagate forward (i.e., with the jet), whereas backward propagation is found outside that core region. Although super-magnetosonic flows are detected by MMS in the spacecraft frame of reference, no fast shock is seen as the jet plasma is sub-magnetosonic with respect to the ambient magnetosheath plasma. Instead, the fast jet plasma pushes ambient magnetosheath plasma ahead of the jet out of the way, possibly generating anomalous sunward flows in the vicinity, and modifies the magnetic field aligning it with the direction of jet propagation.

  8. Marine Jet

    NASA Technical Reports Server (NTRS)

    1978-01-01

    The marine turbine pump pictured is the Jacuzzi 12YJ, a jet propulsion system for pleasure or commercial boating. Its development was aided by a NASA computer program made available by the Computer Software Management and Information Center (COSMIC) at the University of Georgia. The manufacturer, Jacuzzi Brothers, Incorporated, Little Rock, Arkansas, used COSMIC'S Computer Program for Predicting Turbopump Inducer Loading, which enabled substantial savings in development time and money through reduction of repetitive testing.

  9. A Wavelength Modulated, Continuum Excited Furnance Atomic Fluorescence System for the Determination of Wear Metals in Jet Engine Lubricating Oils.

    DTIC Science & Technology

    1980-01-01

    ting Oils 6. PERFORMING 04G. REPORT NUMBER -7 AUTHOR(s) 8 . CONTRACT OR GRANT NUMBER(s) O /Thomna-s F. Wynn, Jr: Capt, USAF 9. PERFORMING ORGANIZATION...EXCITED FURNACE ATOMIC FLUORESCENCE SYSTEM FOR THE DETERMINATION OF WEAR METALS IN JET ENGINE LUBRICATING OILS \\Ac ces-.ic’flr For DDC TL3 Unp-nnounced...DETERMINATION OF WEAR METALS IN JET ENGINE LUBRICATING OILS By Thomas F. Wynn, Jr. March, 1980 Chairman: James D. Winefordner Major Department: Chemistry A

  10. Oxynitrides decorated 316L SS for potential bioimplant application

    NASA Astrophysics Data System (ADS)

    Saravanan Kaliaraj, Gobi; Kumar, N.

    2018-03-01

    Titanium oxynitride (TiON) and zirconium oxynitride (ZrON) were deposited onto 316L stainless steel (316L SS) using reactive magnetron sputtering technique. The monoclinic and cubic phase of TiON and ZrON were obtained by x-ray diffraction (XRD). Nanoindentation and wear test analysis exhibited the better mechanical properties of TiON and ZrON films. Wettability studies showed hydrophilic nature on coated films; whereas bare 316L SS substrate was least hydrophilic. Drastic reduction of bacterial adhesion (Pseudomonas aeruginosa), as well as biofilm formation, was observed in both the films at different time duration. TiON and ZrON films were exhibited excellent hemocompatibility by preventing the platelet activation. Furthermore, the coated films exhibited corrosion protection in presence and absence of hydrogen peroxide (H2O2) in artificial blood plasma (ABP) solution.

  11. Applying Hanford Tank Mixing Data to Define Pulse Jet Mixer Operation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wells, Beric E.; Bamberger, Judith A.; Recknagle, Kurtis P.

    Pulse jet mixed (PJM) process vessels are being developed for storing, blending, and chemical processing of nuclear waste slurries at the Waste Treatment and Immobilization Plant (WTP) to be built at Hanford, Washington. These waste slurries exhibit variable process feed characteristics including Newtonian to non-Newtonian rheologies over a range of solids loadings. Waste feed to the WTP from the Hanford Tank Farms will be accomplished via the Waste Feed Delivery (WFD) system which includes million-gallon underground storage double-shell tanks (DSTs) with dual-opposed jet mixer pumps. Experience using WFD type jet mixer pumps to mobilize actual Hanford waste in DSTs maymore » be used to establish design threshold criteria of interest to pulse jet mixed process vessel operation. This paper describes a method to evaluate the pulse jet mixed vessel capability to process waste based on information obtained during mobilizing and suspending waste by the WFD system jet mixer pumps in a DST. Calculations of jet velocity and wall shear stress in a specific pulse jet mixed process vessel were performed using a commercial computational fluid dynamics (CFD) code. The CFD-modelled process vessel consists of a 4.9-m- (16-ft-) diameter tank with a 2:1 semi-elliptical head, a single, 10-cm (4-in.) downward facing 60-degree conical nozzle, and a 0.61-m (24-in.) inside diameter PJM. The PJM is located at 70% of the vessel radius with the nozzle stand-off-distance 14 cm (6 in.) above the vessel head. The CFD modeled fluid velocity and wall shear stress can be used to estimate vessel waste-processing performance by comparison to available actual WFD system process data. Test data from the operation of jet mixer pumps in the 23-m (75-ft) diameter DSTs have demonstrated mobilization, solid particles in a sediment matrix were moved from their initial location, and suspension, mobilized solid particles were moved to a higher elevation in the vessel than their initial location, of waste

  12. Refraction of high frequency noise in an arbitrary jet flow

    NASA Technical Reports Server (NTRS)

    Khavaran, Abbas; Krejsa, Eugene A.

    1994-01-01

    Refraction of high frequency noise by mean flow gradients in a jet is studied using the ray-tracing methods of geometrical acoustics. Both the two-dimensional (2D) and three-dimensional (3D) formulations are considered. In the former case, the mean flow is assumed parallel and the governing propagation equations are described by a system of four first order ordinary differential equations. The 3D formulation, on the other hand, accounts for the jet spreading as well as the axial flow development. In this case, a system of six first order differential equations are solved to trace a ray from its source location to an observer in the far field. For subsonic jets with a small spreading angle both methods lead to similar results outside the zone of silence. However, with increasing jet speed the two prediction models diverge to the point where the parallel flow assumption is no longer justified. The Doppler factor of supersonic jets as influenced by the refraction effects is discussed and compared with the conventional modified Doppler factor.

  13. Microscopic Processes On Radiation from Accelerated Particles in Relativistic Jets

    NASA Technical Reports Server (NTRS)

    Nishikawa, K.-I.; Hardee, P. E.; Mizuno, Y.; Medvedev, M.; Zhang, B.; Sol, H.; Niemiec, J.; Pohl, M.; Nordlund, A.; Fredriksen, J.; hide

    2009-01-01

    Nonthermal radiation observed from astrophysical systems containing relativistic jets and shocks, e.g., gamma-ray bursts (GRBs), active galactic nuclei (AGNs), and Galactic microquasar systems usually have power-law emission spectra. Recent PIC simulations of relativistic electron-ion (electro-positron) jets injected into a stationary medium show that particle acceleration occurs within the downstream jet. In the collisionless relativistic shock particle acceleration is due to plasma waves and their associated instabilities (e.g., the Buneman instability, other two-streaming instability, and the Weibel (filamentation) instability) created in the shocks are responsible for particle (electron, positron, and ion) acceleration. The simulation results show that the Weibel instability is responsible for generating and amplifying highly nonuniform, small-scale magnetic fields. These magnetic fields contribute to the electron's transverse deflection behind the jet head. The jitter'' radiation from deflected electrons has different properties than synchrotron radiation which is calculated in a uniform magnetic field. This jitter radiation may be important to understanding the complex time evolution and/or spectral structure in gamma-ray bursts, relativistic jets, and supernova remnants.

  14. Jets Galore

    NASA Image and Video Library

    2010-11-04

    This enhanced image, one of the closest taken of comet Harley 2 by NASA EPOXI mission, shows jets and where they originate from the surface. There are jets outgassing from the sunward side, the night side, and along the terminator.

  15. Biomechanical properties of the forefoot plantar soft tissue as measured by an optical coherence tomography-based air-jet indentation system and tissue ultrasound palpation system.

    PubMed

    Chao, Clare Y L; Zheng, Yong-Ping; Huang, Yan-Ping; Cheing, Gladys L Y

    2010-07-01

    The forefoot medial plantar area withstand high plantar pressure during locomotion, and is a common site that develops foot lesion problems among elderly people. The aims of the present study were to (1) determine the correlation between the biomechanical properties of forefoot medial plantar soft tissue measured by a newly developed optical coherence tomography-based air-jet indentation system and by tissue ultrasound palpation system, and (2) to compare the biomechanical properties of plantar soft tissues of medial forefoot between a young and old adult group. Thirty healthy subjects were classified as the young or older group. The biomechanical properties of plantar soft tissues measured at the forefoot by the air-jet indentation system and tissue ultrasound palpation system were performed, and the correlation of the findings obtained in the two systems were compared. A strong positive correlation was obtained from the findings in the two systems (r=0.88, P<0.001). The forefoot plantar soft tissue of the older group was significantly stiffer at the second metatarsal head and thinner at both metatarsal heads than that of the young group (all P<0.05). The stiffness coefficient at the second metatarsal head was 28% greater than that at the first metatarsal head in both study groups. Older subjects showed a loss of elasticity and reduced thickness in their forefoot plantar soft tissue, with the second metatarsal head displaying stiffer and thicker plantar tissue than the first metatarsal head. The air-jet indentation system is a useful instrument for characterizing the biomechanical properties of soft tissue. Copyright (c) 2010 Elsevier Ltd. All rights reserved.

  16. Hard-rock jetting. Part 2. Rock type decides jetting economics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pols, A.C.

    1977-02-07

    In Part 2, Koninklijke Shell Exploratie en Produktie Laboratorium presents the results of jet-drilling laminated formations. Shell concludes that (1) hard, laminated rock cannot be jet-drilled satisfactorily without additional mechanical cutting aids, (2) the increase in penetration rate with bit-pressure drop is much lower for impermeable rock than it is for permeable rock, (3) drilling mud can have either a positive or a negative effect on penetration rate in comparison with water, depending on the material drilled, and (4) hard, isotropic, sedimentary, impermeable rock can be drilled using jets at higher rates than with conventional means. However, jetting becomes profitablemore » only in the case of expensive rigs.« less

  17. Consolidating NASA's Arc Jets

    NASA Technical Reports Server (NTRS)

    Balboni, John A.; Gokcen, Tahir; Hui, Frank C. L.; Graube, Peter; Morrissey, Patricia; Lewis, Ronald

    2015-01-01

    The paper describes the consolidation of NASA's high powered arc-jet testing at a single location. The existing plasma arc-jet wind tunnels located at the Johnson Space Center were relocated to Ames Research Center while maintaining NASA's technical capability to ground-test thermal protection system materials under simulated atmospheric entry convective heating. The testing conditions at JSC were reproduced and successfully demonstrated at ARC through close collaboration between the two centers. New equipment was installed at Ames to provide test gases of pure nitrogen mixed with pure oxygen, and for future nitrogen-carbon dioxide mixtures. A new control system was custom designed, installed and tested. Tests demonstrated the capability of the 10 MW constricted-segmented arc heater at Ames meets the requirements of the major customer, NASA's Orion program. Solutions from an advanced computational fluid dynamics code were used to aid in characterizing the properties of the plasma stream and the surface environment on the calorimeters in the supersonic flow stream produced by the arc heater.

  18. CUSP-SHAPED STRUCTURE OF A JET OBSERVED BY IRIS AND SDO

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhang, Yuzong; Zhang, Jun, E-mail: yuzong@nao.cas.cn, E-mail: zjun@nao.cas.cn

    2017-01-01

    On 2014 August 29, the trigger and evolution of a cusp-shaped jet were captured in detail at 1330 Å by the Interface Region Imaging Spectrograph . At first, two neighboring mini-prominences arose in turn from the low solar atmosphere and collided with a loop-like system over them. The collisions between the loop-like system and the mini-prominences lead to the blowout, and then a cusp-shaped jet formed with a spire and an arch-base. In the spire, many brightening blobs originating from the junction between the spire and the arch-base moved upward in a rotating manner and then in a straight line inmore » the late phase of the jet. In the arch-base, dark and bright material simultaneously tracked in a fan-like structure, and the majority of the material moved along the fan's threads. At the later phase of the jet's evolution, bidirectional flows emptied the arch-base, while downflows emptied the spire, thus making the jet entirely vanish. The extremely detailed observations in this study shed new light on how magnetic reconnection alters the inner topological structure of a jet and provides a beneficial complement for understanding current jet models.« less

  19. Analysis of the effects of firing Orbiter primary reaction control system jets with an attached truss structure

    NASA Technical Reports Server (NTRS)

    Kaszubowski, M.; Raney, J. P.

    1986-01-01

    A study was conducted to determine the dynamic effects of firing the orbiter primary reaction control jets during assembly of protoflight space station structure. Maximum longeron compressive load was calculated as a function of jet pulse time length, number of jet pulses, and total torque imposed by the reaction control jets. The study shows that it is possible to fire selected jets to achieve a pitch maneuver without causing failure of the attached structure.

  20. QUANTIFYING THE CARBON ABUNDANCES IN THE SECONDARY STARS OF SS CYGNI, RU PEGASI, AND GK PERSEI

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Harrison, Thomas E.; Hamilton, Ryan T., E-mail: tharriso@nmsu.edu, E-mail: rthamilton@sofia.usra.edu

    We use a modified version of MOOG to generate large grids of synthetic spectra in an attempt to derive quantitative abundances for three CVs (GK Per, RU Peg, and SS Cyg) by comparing the models to moderate resolution (R ∼ 25,000) K-band spectra obtained with NIRSPEC on Keck. For each of the three systems we find solar, or slightly sub-solar values for [Fe/H], but significant deficits of carbon: for SS Cyg we find [C/Fe] = −0.50, for RU Peg [C/Fe] = −0.75, and for GK Per [C/Fe] = −1.00. We show that it is possible to use lower resolution (Rmore » ∼ 2000) spectra to quantify carbon deficits. We examine realistic veiling scenarios and find that emission from H i or CO cannot reproduce the observations.« less

  1. Real jet effects on dual jets in a crossflow

    NASA Technical Reports Server (NTRS)

    Schetz, J. A.

    1984-01-01

    A 6-ft by 6-ft wind tunnel section was modification to accommodate the 7-ft wide NASA dual-jet flate model in an effort to determine the effects of nonuniform and/or noncircular jet exhaust profiles on the pressure field induced on a nearby surface. Tests completed yield surface pressure measurements for a 90 deg circular injector producing exit profiles representative of turbofan nozzles (such as the TF-34 nozzle). The measurements were obtained for both tandem and side-by-side jet configurations, jet spacing of S/D =2, and velocity ratios of R=2.2 and 4.0. Control tests at the same mass flow rate but with uniform exit velocity profiles were also conducted, for comparison purposes. Plots for 90 deg injection and R=2.2 show that the effects of exit velocity profile nonuniformity are quite significant.

  2. Behavior of a wave-driven buoyant surface jet on a coral reef

    USGS Publications Warehouse

    Herdman, Liv; Hench, James L.; Fringer, Oliver; Monismith, Stephen G.

    2017-01-01

    A wave-driven surface buoyant jet exiting a coral reef was studied in order to quantify the amount of water re-entrained over the reef crest. Both moored observations and Lagrangian drifters were used to study the fate of the buoyant jet. To investigate in detail the effects of buoyancy and along-shore flow variations, we developed an idealized numerical model of the system. Consistent with previous work, the ratio of along-shore velocity to jet-velocity and the jet internal Froude number were found to be important determinants of the fate of the jet. In the absence of buoyancy, the entrainment of fluid at the reef crest, creates a significant amount of retention, keeping 60% of water in the reef system. However, when the jet is lighter than the ambient ocean-water, the net effect of buoyancy is to enhance the separation of the jet from shore, leading to a greater export of reef water. Matching observations, our modeling predicts that buoyancy limits retention to 30% of the jet flow for conditions existing on the Moorea reef. Overall, the combination of observations and modeling we present here shows that reef-ocean temperature gradients can play an important role in reef-ocean exchanges.

  3. Behavior of a wave-driven buoyant surface jet on a coral reef

    NASA Astrophysics Data System (ADS)

    Herdman, Liv M. M.; Hench, James L.; Fringer, Oliver; Monismith, Stephen G.

    2017-05-01

    A wave-driven surface-buoyant jet exiting a coral reef was studied in order to quantify the amount of water reentrained over the reef crest. Both moored observations and Lagrangian drifters were used to study the fate of the buoyant jet. To investigate in detail the effects of buoyancy and alongshore flow variations, we developed an idealized numerical model of the system. Consistent with previous work, the ratio of alongshore velocity to jet velocity and the jet internal Froude number were found to be important determinants of the fate of the jet. In the absence of buoyancy, the entrainment of fluid at the reef crest creates a significant amount of retention, keeping 60% of water in the reef system. However, when the jet is lighter than the ambient ocean water, the net effect of buoyancy is to enhance the separation of the jet from shore, leading to a greater export of reef water. Matching observations, our modeling predicts that buoyancy limits retention to 30% of the jet flow for conditions existing on the Moorea reef. Overall, the combination of observations and modeling we present here shows that reef-ocean temperature gradients can play an important role in reef-ocean exchanges.

  4. Study Of Boosted W-Jets And Higgs-Jets With the SiFCC Detector

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yu, Shin-Shan; Chekanov, Sergei; Gray, Lindsey

    We study the detector performance in the reconstruction of hadronically-decaying W bosons and Higgs bosons at very high energy proton colliders using a full GEANT4 simulation of the SiFCC detector. The W and Higgs bosons carry transverse momentum in the multi-TeV range, which results in collimated decay products that are reconstructed as a single jet. We present a measurement of the energy response and resolution of boosted W-jets and Higgs-jets and show the separation of two sub-jets within the boosted boson jet.

  5. Microstructural and Electrochemical Evaluation of Fusion Welded Low-Nickel and 304 SS at Different Heat Input

    NASA Astrophysics Data System (ADS)

    Bansod, Ankur V.; Patil, Awanikumar P.; Moon, Abhijeet P.; Shukla, Sourabh

    2017-12-01

    The present research study investigates the effect of heat input using E 308 electrode (controlled by welding current, i.e., 70, 85 and 100 A) on microstructure, mechanical properties and corrosion behavior of low-nickel and 304 stainless steel (SS) weldments produced by shielded metal arc welding technique. SEM investigation shows that with the higher heat input, δ-ferrite content was reduced. Dendrite and inter-dendritic length is also reduced by lowering the heat input. For all the heat inputs, it is observed that δ-ferrite content was higher in 304 stainless steel (SS) as compared to that of low-nickel austenitic stainless steel (Cr-Mn SS). Considering the heat input for Cr-Mn SS, coarse grains were observed in the heat-affected zone region. For low heat input (LHI), tensile fracture surface has exhibited river-like pattern with dimple appearance. Corrosion studies show better pitting resistance for low heat input (LHI) samples due to higher δ-ferrite present in the weld region. Similarly, higher interphase corrosion resistance is observed in both the SS grades causing more dissolution in the LHI samples.

  6. An Experimental/Modeling Study of Jet Attachment during Counterflow Thrust Vectoring

    NASA Technical Reports Server (NTRS)

    Strykowski, Paul J.

    1997-01-01

    Recent studies have shown the applicability of vectoring rectangular jets using asymmetrically applied counterflow in the presence of a short collar. This novel concept has applications in the aerospace industry where counterflow can be used to vector the thrust of a jet's exhaust, shortening take-off and landing distances and enhancing in-flight maneuverability of the aircraft. Counterflow thrust vectoring, 'CFTV' is desirable due to its fast time response, low thrust loss, and absence of moving parts. However, implementation of a CFTV system is only possible if bistable jet attachment can be prevented. This can be achieved by properly designing the geometry of the collar. An analytical model is developed herein to predict the conditions under which a two-dimensional jet will attach to an offset curved wall. Results from this model are then compared with experiment; for various jet exit Mach numbers, collar offset distances, and radii of curvature. Their excellent correlation permits use of the model as a tool for designing a CFTV system.

  7. PU/SS EUTECTIC ASSESSMENT IN 9975 PACKAGINGS IN A STORAGE FACILITY DURING EXTENDED FIRE

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gupta, N.

    2012-03-26

    In a radioactive material (RAM) packaging, the formation of eutectic at the Pu/SS (plutonium/stainless steel) interface is a serious concern and must be avoided to prevent of leakage of fissile material to the environment. The eutectic temperature for the Pu/SS is rather low (410 C) and could seriously impact the structural integrity of the containment vessel under accident conditions involving fire. The 9975 packaging is used for long term storage of Pu bearing materials in the DOE complex where the Pu comes in contact with the stainless steel containment vessel. Due to the serious consequences of the containment breach atmore » the eutectic site, the Pu/SS interface temperature is kept well below the eutectic formation temperature of 410 C. This paper discusses the thermal models and the results for the extended fire conditions (1500 F for 86 minutes) that exist in a long term storage facility and concludes that the 9975 packaging Pu/SS interface temperature is well below the eutectic temperature.« less

  8. Role of T3SS-1 SipD Protein in Protecting Mice against Non-typhoidal Salmonella Typhimurium

    PubMed Central

    Jneid, Bakhos; Moreau, Karine; Plaisance, Marc; Rouaix, Audrey; Dano, Julie

    2016-01-01

    Background Salmonella enterica species are enteric pathogens that cause severe diseases ranging from self-limiting gastroenteritis to enteric fever and sepsis in humans. These infectious diseases are still the major cause of morbidity and mortality in low-income countries, especially in children younger than 5 years and immunocompromised adults. Vaccines targeting typhoidal diseases are already marketed, but none protect against non-typhoidal Salmonella. The existence of multiple non-typhoidal Salmonella serotypes as well as emerging antibiotic resistance highlight the need for development of a broad-spectrum protective vaccine. All Salmonella spp. utilize two type III Secretion Systems (T3SS 1 and 2) to initiate infection, allow replication in phagocytic cells and induce systemic disease. T3SS-1, which is essential to invade epithelial cells and cross the barrier, forms an extracellular needle and syringe necessary to inject effector proteins into the host cell. PrgI and SipD form, respectively, the T3SS-1 needle and the tip complex at the top of the needle. Because they are common and highly conserved in all virulent Salmonella spp., they might be ideal candidate antigens for a subunit-based, broad-spectrum vaccine. Principal Findings We investigated the immunogenicity and protective efficacy of PrgI and SipD administered by subcutaneous, intranasal and oral routes, alone or combined, in a mouse model of Salmonella intestinal challenge. Robust IgG (in all immunization routes) and IgA (in intranasal and oral immunization routes) antibody responses were induced against both proteins, particularly SipD. Mice orally immunized with SipD alone or SipD combined with PrgI were protected against lethal intestinal challenge with Salmonella Typhimurium (100 Lethal Dose 50%) depending on antigen, route and adjuvant. Conclusions and Significance Salmonella T3SS SipD is a promising antigen for the development of a protective Salmonella vaccine, and could be developed for

  9. Dripping and jetting regimes in co-flowing capillary jets: unforced measurements and response to driving

    NASA Astrophysics Data System (ADS)

    Baroud, Charles; Cordero, Maria-Luisa; Gallaire, Francois

    2011-11-01

    We study the breakup of drops in a co-flowing jet, within the confinement of a microfluidic channel. The breakup can occur right after the nozzle (dripping) or through the generation of a liquid jet that breaks up a long distance from the nozzle (jetting). Traditionally, these two regimes have been considered to reflect an absolutely unstable jet or a convectively unstable jet, respectively. We first provide measurements of the frequency of oscillation and breakup of the liquid jet; the dispersion relation thus obtained compares well with existing theories for convective instabilities in the case of the jetting regime. However, the theories in the absolutely unstable mode fail to predict the evolution of the frequency and drop size in the dripping regime. We also test the jet response to an external forcing, using a focused laser to locally heat the jet. The dripping regime is found to be insensitive to the perturbation and the frequency of drop formation remains unaltered. In contrast, the jetting regime locks to the external frequency, which translates into a modification of the drop size in agreement with the dispersion relations. This confirms the convective nature of the jetting regime. Permanent address: Universidad de Chile.

  10. Resolving boosted jets with XCone

    DOE PAGES

    Thaler, Jesse; Wilkason, Thomas F.

    2015-12-01

    We show how the recently proposed XCone jet algorithm smoothly interpolates between resolved and boosted kinematics. When using standard jet algorithms to reconstruct the decays of hadronic resonances like top quarks and Higgs bosons, one typically needs separate analysis strategies to handle the resolved regime of well-separated jets and the boosted regime of fat jets with substructure. XCone, by contrast, is an exclusive cone jet algorithm that always returns a fixed number of jets, so jet regions remain resolved even when (sub)jets are overlapping in the boosted regime. In this paper, we perform three LHC case studies $-$ dijet resonances,more » Higgs decays to bottom quarks, and all-hadronic top pairs$-$ that demonstrate the physics applications of XCone over a wide kinematic range.« less

  11. Simulations of Solar Jets

    NASA Astrophysics Data System (ADS)

    Kohler, Susanna

    2017-02-01

    Formation of a coronal jet from twisted field lines that have reconnected with the ambient field. The colors show the radial velocity of the plasma. [Adapted from Szente et al. 2017]How do jets emitted from the Suns surface contribute to its corona and to the solar wind? In a recent study, a team of scientists performed complex three-dimensional simulations of coronal jets to answer these questions.Small ExplosionsCoronal jets are relatively small eruptions from the Suns surface, with heights of roughly 100 to 10,000 km, speeds of 10 to 1,000 km/s, and lifetimes of a few minutes to around ten hours. These jets are constantly present theyre emitted even from the quiet Sun, when activity is otherwise low and weve observed them with a fleet of Sun-watching space telescopes spanning the visible, extreme ultraviolet (EUV), and X-ray wavelength bands.A comparison of simulated observations based on the authors model (left panels) to actual EUV and X-ray observations of jets (right panels). [Szente et al. 2017]Due to their ubiquity, we speculate that these jets might contribute to heating the global solar corona (which is significantly hotter than the surface below it, a curiosity known as the coronal heating problem). We can also wonder what role these jets might play in driving the overall solar wind.Launching a JetLed by Judit Szente (University of Michigan), a team of scientists has explored the impact of coronal jets on the global corona and solar wind with a series of numerical simulations. Szente and collaborators used three-dimensional, magnetohydrodynamic simulations that provide realistic treatment of the solar atmosphere, the solar wind acceleration, and the complexities of heat transfer throughout the corona.In the authors simulations, a jet is initiated as a magnetic dipole rotates at the solar surface, winding up field lines. Magnetic reconnection between the twisted lines and the background field then launches the jet from the dense and hot solar

  12. Airframe-Jet Engine Integration Noise

    NASA Technical Reports Server (NTRS)

    Tam, Christopher; Antcliff, Richard R. (Technical Monitor)

    2003-01-01

    It has been found experimentally that the noise radiated by a jet mounted under the wing of an aircraft exceeds that of the same jet in a stand-alone environment. The increase in noise is referred to as jet engine airframe integration noise. The objectives of the present investigation are, (1) To obtain a better understanding of the physical mechanisms responsible for jet engine airframe integration noise or installation noise. (2) To develop a prediction model for jet engine airframe integration noise. It is known that jet mixing noise consists of two principal components. They are the noise from the large turbulence structures of the jet flow and the noise from the fine scale turbulence. In this investigation, only the effect of jet engine airframe interaction on the fine scale turbulence noise of a jet is studied. The fine scale turbulence noise is the dominant noise component in the sideline direction. Thus we limit out consideration primarily to the sideline.

  13. Connections Between Jet Formation and Multiwavelength Spectral Evolution in Black Hole Transients

    NASA Technical Reports Server (NTRS)

    Kakemci, Emrah; Chun, Yoon-Young; Dincer, Tolga; Buxton, Michelle; Tomsick, John A.; Corbel, Stephane; Kaaret, Philip

    2011-01-01

    Multiwavelength observations are the key to understand conditions of jet formation in Galactic black hole transient (GBHT) systems. By studying radio and optical-infrared evolution of such systems during outburst decays, the compact jet formation can be traced. Comparing this with X-ray spectral and timing evolution we can obtain physical and geometrical conditions for jet formation, and study the contribution of jets to X-ray emission. In this work, first X-ray evolution - jet relation for XTE J1752-223 will be discussed. This source had very good coverage in X-rays, optical, infrared and radio. A long exposure with INTEGRAL also allowed us to study gamma-ray behavior after the jet turns on. We will also show results from the analysis of data from GX 339-4 in the hard state with SUZAKU at low flux levels. The fits to iron line fluorescence emission show that the inner disk radius increases by a factor of greater than 27 with respect to radii in bright states. This result, along with other disk radius measurements in the hard state will be discussed within the context of conditions for launching and sustaining jets.

  14. Jet-front systems nearing strongly stratified region in differentially heated, rotating stratified annulus

    NASA Astrophysics Data System (ADS)

    Rolland, Joran; Achatz, Ulrich

    2017-04-01

    The differentially heated, rotating annulus configuration has been used for a long time as a model system of the earth troposphere. It can easily reproduce thermal wind and baroclinic waves in the laboratory. It has recently been shown numerically that provided the Rossby number, the rotation rate and the Brunt-Väisälä frequency were well chosen, this configuration also reproduces the spontaneous emission of gravity waves by jet front systems [1]. This offers a very practical configuration in which to study an important process of emission of atmospheric gravity waves. It has also been shown experimentally that this configuration can be modified in order to add the possibility for the emitted wave to reach a strongly stratified region [2]. It thus creates a system containing a model troposphere where gravity waves are spontaneously emitted and can propagate to a model stratosphere. For this matter a stratification was created using a salinity gradient in the experimental apparatus. Through double diffusion, this generates a strongly stratified layer in the middle of the flow (the model stratosphere) and two weakly stratified region in the top and bottom layers (the model troposphere). In this poster, we present simulations of this configuration displaying baroclinic waves in the top and bottom layers. We aim at creating jet front systems strong enough that gravity waves can be spontaneously emitted. This will thus offer the possibility of studying the wave characteristic and mechanisms in emission and propagation in details. References [1] S. Borchert, U. Achatz, M.D. Fruman, Spontaneous Gravity wave emission in the differentially heated annulus, J. Fluid Mech. 758, 287-311 (2014). [2] M. Vincze, I. Borcia, U. Harlander, P. Le Gal, Double-diffusive convection convection and baroclinic instability in a differentially heated and initially stratified rotating system: the barostrat instability, Fluid Dyn. Res. 48, 061414 (2016).

  15. On the origin of X-ray variability of SS 433

    NASA Astrophysics Data System (ADS)

    Band, D. L.; Grindlay, J. E.

    1984-10-01

    The X-ray flares observed from the central source in SS 433 by the Einstein telescope are attributed to surges in the mass transfer rate due to changes in the critical Roche volume of the companion. Analysis of the Roche potential for a primary with spin misaligned with the orbital axis, as required by the slaved disk model, predicts that the critical Roche volume will contract twice per orbit if the orbit is circular. A critical Roche volume fractional change of 1-2 percent is found by applying this potential to SS 433. The nutation of the companion should not affect the steady precession of its spin. Aspects of this work strengthen the evidence that the compact object might be a black hole.

  16. Test launch of a Topol/SS-25 missile

    NASA Image and Video Library

    2013-10-10

    View of test launch of a Topol/SS-25 missile on Oct. 10, 2013 as seen by the Expedition 37 crew aboard the International Space Station (ISS). The missile was launched at 17:39 MSK (13:39 UTC) from Kapustin Yar to the Sary Shagan test site in Kazakhstan. Also sent as Twitter message.

  17. Microstructure and Corrosion Behavior of Laser Melted 304L SS Weldment in Nitric Acid Medium

    NASA Astrophysics Data System (ADS)

    Suresh, Girija; Kishor, P. S. V. R. A.; Dasgupta, Arup; Upadhyay, B. N.; Mallika, C.; Kamachi Mudali, U.

    2017-02-01

    The manuscript presents the effect of laser surface melting on the corrosion property of 304L SS weldment in nitric acid medium. 304L SS weldment was prepared by gas tungsten arc welding process and subsequently laser surface melted using Nd:YAG laser. The microstructure and corrosion resistance of laser surface melted 304L SS weldment was evaluated and compared with that of 304L SS as-weldment and 304L SS base. Microstructural evaluation was carried out using optical and scanning electron microscopes attached with energy-dispersive x-ray spectroscopy. Corrosion investigations were carried out in 4 and 8 M nitric acid by potentiodynamic polarization technique. From the results, it was found that laser surface melting of the weldment led to chemical and microstructural homogeneities, accompanied by a substantial decrease in delta ferrite content, that enhanced the corrosion resistance of the weldment in 4 and 8 M nitric acid. However, the enhancement in the corrosion resistance was not substantial. The presence of small amount of delta ferrite (2-4 wt.%) in the laser surface melted specimens was found to be detrimental in nitric acid. X-ray photoelectron spectroscopy studies were carried out to investigate the composition of the passive film.

  18. High Performance Simulations of Accretion Disk Dynamics and Jet Formations Around Kerr Black Holes

    NASA Technical Reports Server (NTRS)

    Nishikawa, Ken-Ichi; Mizuno, Yosuke; Watson, Michael

    2007-01-01

    We investigate jet formation in black-hole systems using 3-D General Relativistic Particle-In-Cell (GRPIC) and 3-D GRMHD simulations. GRPIC simulations, which allow charge separations in a collisionless plasma, do not need to invoke the frozen condition as in GRMHD simulations. 3-D GRPIC simulations show that jets are launched from Kerr black holes as in 3-D GRMHD simulations, but jet formation in the two cases may not be identical. Comparative study of black hole systems with GRPIC and GRMHD simulations with the inclusion of radiate transfer will further clarify the mechanisms that drive the evolution of disk-jet systems.

  19. Pregnancy outcome in patients with sickle cell disease in the UK--a national cohort study comparing sickle cell anaemia (HbSS) with HbSC disease.

    PubMed

    Oteng-Ntim, Eugene; Ayensah, Benjamin; Knight, Marian; Howard, Jo

    2015-04-01

    We describe the findings from a national study of maternal and fetal outcomes of pregnancy in women with sickle cell disease (SCD). Data were collected via the United Kingdom Obstetric Surveillance System between 1 February 2010 and 31 January 2011 from 109 women, of whom 51 (46·8%) had HbSS and 44 (40·4%) had HbSC. Data included antenatal, maternal and fetal outcomes. Comparisons were made between women with HbSS and HbSC. Incidence of complications were acute pain (57%), blood transfusion (26%), urinary tract infection (UTI; 12%) and critical care unit admission (23%) and these were all more common in women with HbSS than HbSC. There was no difference in the incidence of acute chest syndrome, hypertension and venous thromboembolism between HbSS and HbSC. Women with HbSS were more likely to deliver at <37 weeks gestation (P = 0·01) and their babies were more likely to have reduced birth weight. Delivery at <34 weeks was increased in both HbSS and HbSC women (5·9% vs. 4·6%) compared to national data. This study confirms a high rate of maternal and fetal complications in mothers with SCD, even in women with HbSC, which has previously been considered to have a more benign phenotype in pregnancy. © 2014 John Wiley & Sons Ltd.

  20. Jet impingement heat transfer enhancement for the GPU-3 Stirling engine

    NASA Technical Reports Server (NTRS)

    Johnson, D. C.; Congdon, C. W.; Begg, L. L.; Britt, E. J.; Thieme, L. G.

    1981-01-01

    A computer model of the combustion-gas-side heat transfer was developed to predict the effects of a jet impingement system and the possible range of improvements available. Using low temperature (315 C (600 F)) pretest data in an updated model, a high temperature silicon carbide jet impingement heat transfer system was designed and fabricated. The system model predicted that at the theoretical maximum limit, jet impingement enhanced heat transfer can: (1) reduce the flame temperature by 275 C (500 F); (2) reduce the exhaust temperature by 110 C (200 F); and (3) increase the overall heat into the working fluid by 10%, all for an increase in required pumping power of less than 0.5% of the engine power output. Initial tests on the GPU-3 Stirling engine at NASA-Lewis demonstrated that the jet impingement system increased the engine output power and efficiency by 5% - 8% with no measurable increase in pumping power. The overall heat transfer coefficient was increased by 65% for the maximum power point of the tests.

  1. Application of thermophilic enzymes and water jet system to cassava pulp.

    PubMed

    Chaikaew, Siriporn; Maeno, Yuka; Visessanguan, Wonnop; Ogura, Kota; Sugino, Gaku; Lee, Seung-Hwan; Ishikawa, Kazuhiko

    2012-12-01

    Co-production of fermentable sugars and nanofibrillated cellulose from cassava pulp was achieved by the combination of thermophilic enzymes (endoglucanase, β-glucosidase, and α-amylase) and a new atomization system (Star Burst System; SBS), which employs opposing water jets. The SBS represents a key technology for providing cellulose nanofibers and improving the enzymatic saccharification of cassava pulp. Depending on the enzymes used, the production of glucose from cassava pulp treated with the SBS was 1.2- to 2.5-fold higher than that from pulp not treated with the SBS. Nanofibrillated cellulose with the gel-like property in suspension was produced (yield was over 90%) by α-amylase treatment, which completely released trapped starch granules from the fibrous cell wall structure of cassava pulp pretreated with the SBS. The SBS provides an environmentally low-impact pretreatment system for processing biomass material into value-added products. Copyright © 2012 Elsevier Ltd. All rights reserved.

  2. A PIONIER and Incisive Look at the Interacting Binary SS Lep

    NASA Astrophysics Data System (ADS)

    Blind, N.; Boffin, H. M. J.; Berger, J.-P.; Lebouquin, J.-B.; Mérand, A.

    2011-09-01

    Symbiotic stars are excellent laboratories to study a broad range of poorly understood physical processes, such as mass loss of red giants, accretion onto compact objects, and evolution of nova-like outbursts. As their evolution is strongly influenced by the mass transfer episodes, understanding the history of these systems requires foremost to determine which process is at play: Roche lobe overflow, stellar wind accretion, or some more complex mixture of both. We report here an interferometric study of the symbiotic system SS Leporis, performed with the unique PIONIER instrument. By determining the binary orbit and revisiting the parameters of the two stars, we show that the giant does not fill its Roche lobe, and that the mass transfer most likely occurs via the accretion of an important part of the giant's wind.

  3. ssDNA degradation along capillary electrophoresis process using a Tris buffer.

    PubMed

    Ric, Audrey; Ong-Meang, Varravaddheay; Poinsot, Verena; Martins-Froment, Nathalie; Chauvet, Fabien; Boutonnet, Audrey; Ginot, Frédéric; Ecochard, Vincent; Paquereau, Laurent; Couderc, François

    2017-06-01

    Tris-Acetate buffer is currently used in the selection and the characterization of ssDNA by capillary electrophoresis (CE). By applying high voltage, the migration of ionic species into the capillary generates a current that induces water electrolysis. This phenomenon is followed by the modification of the pH and the production of Tris derivatives. By injecting ten times by capillary electrophoresis ssDNA (50 nM), the whole oligonucleotide was degraded. In this paper, we will show that the Tris buffer in the running vials is modified along the electrophoretic process by electrochemical reactions. We also observed that the composition of the metal ions changes in the running buffer vials. This phenomenon, never described in CE, is important for fluorescent ssDNA analysis using Tris buffer. The oligonucleotides are degraded by electrochemically synthesized species (present in the running Tris vials) until it disappears, even if the separation buffer in the capillary is clean. To address these issues, we propose to use a sodium phosphate buffer that we demonstrate to be electrochemically inactive. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  4. Reprint of: Reaction measurements with the Jet Experiments in Nuclear Structure and Astrophysics (JENSA) gas jet target

    NASA Astrophysics Data System (ADS)

    Chipps, K. A.

    2018-01-01

    Explosive stellar environments are sometimes driven by nuclear reactions on short-lived, radioactive nuclei. These reactions often drive the stellar explosion, alter the observable light curves produced, and dictate the final abundances of the isotopes created. Unfortunately, many reaction rates at stellar temperatures cannot be directly measured in the laboratory, due to the physical limitations of ultra-low cross sections and high background rates. An additional complication arises because many of the important reactions involve radioactive nuclei which have lifetimes too short to be made into a target. As such, direct reactions require very intense and pure beams of exotic nuclei. Indirect approaches with both stable and radioactive beams can, however, provide crucial information on the nuclei involved in these astrophysical reactions. A major development toward both direct and indirect studies of nuclear reactions rates is the commissioning of the Jet Experiments in Nuclear Structure and Astrophysics (JENSA) supersonic gas jet target. The JENSA system provides a pure, homogeneous, highly localized, dense, and robust gaseous target for radioactive ion beam studies. Charged-particle reactions measurements made with gas jet targets can be cleaner and display better resolution than with traditional targets. With the availability of pure and localized gas jet targets in combination with developments in exotic radioactive ion beams and next-generation detector systems, the range of reaction studies that are experimentally possible is vastly expanded. Various representative cases will be discussed.

  5. The influence of hydrocarbon composition and exposure conditions on jet fuel-induced immunotoxicity.

    PubMed

    Hilgaertner, Jianhua W; He, Xianghui; Camacho, Daniel; Badowski, Michael; Witten, Mark; Harris, David T

    2011-11-01

    Chronic jet fuel exposure could be detrimental to the health and well-being of exposed personnel, adversely affect their work performance and predispose these individuals to increased incidences of infectious disease, cancer and autoimmune disorders. Short-term (7 day) JP-8 jet fuel exposure has been shown to cause lung injury and immune dysfunction. Physiological alterations can be influenced not only by jet fuel exposure concentration (absolute amount), but also are dependent on the type of exposure (aerosol versus vapor) and the composition of the jet fuel (hydrocarbon composition). In the current study, these variables were examined with relation to effects of jet fuel exposure on immune function. It was discovered that real-time, in-line monitoring of jet fuel exposure resulted in aerosol exposure concentrations that were approximately one-eighth the concentration of previously reported exposure systems. Further, the effects of a synthetic jet fuel designed to eliminate polycyclic aromatic hydrocarbons were also examined. Both of these changes in exposure reduced but did not eliminate the deleterious effects on the immune system of exposed mice.

  6. Development of a Jet Noise Prediction Method for Installed Jet Configurations

    NASA Technical Reports Server (NTRS)

    Hunter, Craig A.; Thomas, Russell H.

    2003-01-01

    This paper describes development of the Jet3D noise prediction method and its application to heated jets with complex three-dimensional flow fields and installation effects. Noise predictions were made for four separate flow bypass ratio five nozzle configurations tested in the NASA Langley Jet Noise Laboratory. These configurations consist of a round core and fan nozzle with and without pylon, and an eight chevron core nozzle and round fan nozzle with and without pylon. Predicted SPL data were in good agreement with experimental noise measurements up to 121 inlet angle, beyond which Jet3D under predicted low frequency levels. This is due to inherent limitations in the formulation of Lighthill's Acoustic Analogy used in Jet3D, and will be corrected in ongoing development. Jet3D did an excellent job predicting full scale EPNL for nonchevron configurations, and captured the effect of the pylon, correctly predicting a reduction in EPNL. EPNL predictions for chevron configurations were not in good agreement with measured data, likely due to the lower mixing and longer potential cores in the CFD simulations of these cases.

  7. Experimental study of a vertical jet in a vegetated crossflow.

    PubMed

    Ben Meftah, Mouldi; De Serio, Francesca; Malcangio, Daniela; Mossa, Michele; Petrillo, Antonio Felice

    2015-12-01

    Aquatic ecosystems have long been used as receiving environments of wastewater discharges. Effluent discharge in a receiving water body via single jet or multiport diffuser, reflects a number of complex phenomena, affecting the ecosystem services. Discharge systems need to be designed to minimize environmental impacts. Therefore, a good knowledge of the interaction between effluents, discharge systems and receiving environments is required to promote best environmental management practice. This paper reports innovative 3D flow velocity measurements of a jet discharged into an obstructed crossflow, simulating natural vegetated channel flows for which correct environmental management still lacks in literature. In recent years, numerous experimental and numerical studies have been conducted on vegetated channels, on the one hand, and on turbulent jets discharged into unvegetated crossflows, on the other hand. Despite these studies, however, there is a lack of information regarding jets discharged into vegetated crossflow. The present study aims at obtaining a more thorough understanding of the interaction between a turbulent jet and an obstructed crossflow. In order to achieve such an objective, a series of laboratory experiments was carried out in the Department of Civil, Environmental, Building Engineering and Chemistry of the Technical University of Bari - Italy. The physical model consists of a vertical jet discharged into a crossflow, obstructed by an array of vertical, rigid, circular and threaded steel cylinders. Analysis of the measured flow velocities shows that the array of emergent rigid vegetation significantly affects the jet and the ambient flow structures. It reduces the mean channel velocity, allowing the jet to penetrate higher into the crossflow. It significantly increases the transversal flow motion, promoting a major lateral spreading of the jet within the crossflow. Due to the vegetation array effects, the jet undergoes notable variations in its

  8. Phenomenology of single-inclusive jet production with jet radius and threshold resummation

    NASA Astrophysics Data System (ADS)

    Liu, Xiaohui; Moch, Sven-Olaf; Ringer, Felix

    2018-03-01

    We perform a detailed study of inclusive jet production cross sections at the LHC and compare the QCD theory predictions based on the recently developed formalism for threshold and jet radius joint resummation at next-to-leading logarithmic accuracy to inclusive jet data collected by the CMS Collaboration at √{S }=7 and 13 TeV. We compute the cross sections at next-to-leading order in QCD with and without the joint resummation for different choices of jet radii R and observe that the joint resummation leads to crucial improvements in the description of the data. Comprehensive studies with different parton distribution functions demonstrate the necessity of considering the joint resummation in fits of those functions based on the LHC jet data.

  9. Needle-free delivery of macromolecules through the skin using controllable jet injectors.

    PubMed

    Hogan, Nora C; Taberner, Andrew J; Jones, Lynette A; Hunter, Ian W

    2015-01-01

    Transdermal delivery of drugs has a number of advantages in comparison to other routes of administration. The mechanical properties of skin, however, impose a barrier to administration and so most compounds are administered using hypodermic needles and syringes. In order to overcome some of the issues associated with the use of needles, a variety of non-needle devices based on jet injection technology has been developed. Jet injection has been used primarily for vaccine administration but has also been used to deliver macromolecules such as hormones, monoclonal antibodies and nucleic acids. A critical component in the more recent success of jet injection technology has been the active control of pressure applied to the drug during the time course of injection. Jet injection systems that are electronically controllable and reversible offer significant advantages over conventional injection systems. These devices can consistently create the high pressures and jet speeds necessary to penetrate tissue and then transition smoothly to a lower jet speed for delivery of the remainder of the desired dose. It seems likely that in the future this work will result in smart drug delivery systems incorporated into personal medical devices and medical robots for in-home disease management and healthcare.

  10. Large space antenna communications systems: Integrated Langley Research Center/Jet Propulsion Laboratory technology development activities. 1: Introduction

    NASA Technical Reports Server (NTRS)

    Campbell, T. G.

    1983-01-01

    The Jet Propulsion Laboratory and the Langley Research Center have been developing technology related to large space antennas (LSA) during the past several years. The need for a communication system research program became apparent during the recent studies for the Land Mobile Satellite System. This study indicated the need for additional research in (1) electromagnetic analysis methods, (2) design and development of multiple beam feed systems, and (3) the measurement methods for LSA reflectors.

  11. A user's guide to the ssWavelets package

    Treesearch

    J.H. ​Gove

    2017-01-01

    ssWavelets is an R package that is meant to be used in conjunction with the sampSurf package (Gove, 2012) to perform wavelet decomposition on the results of a sampling surface simulation. In general, the wavelet filter decomposes the sampSurf simulation results by scale (distance), with each scale corresponding to a different level of the...

  12. Developing an Empirical Model for Jet-Surface Interaction Noise

    NASA Technical Reports Server (NTRS)

    Brown, Clifford A.

    2014-01-01

    The process of developing an empirical model for jet-surface interaction noise is described and the resulting model evaluated. Jet-surface interaction noise is generated when the high-speed engine exhaust from modern tightly integrated or conventional high-bypass ratio engine aircraft strikes or flows over the airframe surfaces. An empirical model based on an existing experimental database is developed for use in preliminary design system level studies where computation speed and range of configurations is valued over absolute accuracy to select the most promising (or eliminate the worst) possible designs. The model developed assumes that the jet-surface interaction noise spectra can be separated from the jet mixing noise and described as a parabolic function with three coefficients: peak amplitude, spectral width, and peak frequency. These coefficients are fit to functions of surface length and distance from the jet lipline to form a characteristic spectra which is then adjusted for changes in jet velocity and/or observer angle using scaling laws from published theoretical and experimental work. The resulting model is then evaluated for its ability to reproduce the characteristic spectra and then for reproducing spectra measured at other jet velocities and observer angles; successes and limitations are discussed considering the complexity of the jet-surface interaction noise versus the desire for a model that is simple to implement and quick to execute.

  13. Developing an Empirical Model for Jet-Surface Interaction Noise

    NASA Technical Reports Server (NTRS)

    Brown, Clif

    2014-01-01

    The process of developing an empirical model for jet-surface interaction noise is described and the resulting model evaluated. Jet-surface interaction noise is generated when the high-speed engine exhaust from modern tightly integrated or conventional high-bypass ratio engine aircraft strikes or flows over the airframe surfaces. An empirical model based on an existing experimental database is developed for use in preliminary design system level studies where computation speed and range of configurations is valued over absolute accuracy to select the most promising (or eliminate the worst) possible designs. The model developed assumes that the jet-surface interaction noise spectra can be separated from the jet mixing noise and described as a parabolic function with three coefficients: peak amplitude, spectral width, and peak frequency. These coefficients are t to functions of surface length and distance from the jet lipline to form a characteristic spectra which is then adjusted for changes in jet velocity and/or observer angle using scaling laws from published theoretical and experimental work. The resulting model is then evaluated for its ability to reproduce the characteristic spectra and then for reproducing spectra measured at other jet velocities and observer angles; successes and limitations are discussed considering the complexity of the jet-surface interaction noise versus the desire for a model that is simple to implement and quick to execute.

  14. Operation in the turbulent jet field of a linear array of multiple rectangular jets using a two-dimensional jet (Variation of mean velocity field)

    NASA Astrophysics Data System (ADS)

    Fujita, Shigetaka; Harima, Takashi

    2016-03-01

    The mean flowfield of a linear array of multiple rectangular jets run through transversely with a two-dimensional jet, has been investigated, experimentally. The object of this experiment is to operate both the velocity scale and the length scale of the multiple rectangular jets using a two-dimensional jet. The reason of the adoption of this nozzle exit shape was caused by the reports of authors in which the cruciform nozzle promoted the inward secondary flows strongly on both the two jet axes. Aspect ratio of the rectangular nozzle used in this experiment was 12.5. Reynolds number based on the nozzle width d and the exit mean velocity Ue (≅ 39 m / s) was kept constant 25000. Longitudinal mean velocity was measured using an X-array Hot-Wire Probe (lh = 3.1 μm in diameter, dh = 0.6 mm effective length : dh / lh = 194) operated by the linearized constant temperature anemometers (DANTEC), and the spanwise and the lateral mean velocities were measured using a yaw meter. The signals from the anemometers were passed through the low-pass filters and sampled using A.D. converter. The processing of the signals was made by a personal computer. Acquisition time of the signals was usually 60 seconds. From this experiment, it was revealed that the magnitude of the inward secondary flows on both the y and z axes in the upstream region of the present jet was promoted by a two-dimensional jet which run through transversely perpendicular to the multiple rectangular jets, therefore the potential core length on the x axis of the present jet extended 2.3 times longer than that of the multiple rectangular jets, and the half-velocity width on the rectangular jet axis of the present jet was suppressed 41% shorter compared with that of the multiple rectangular jets.

  15. The ground vortex flow field associated with a jet in a cross flow impinging on a ground plane for uniform and annular turbulent axisymmetric jets. M.S. Thesis

    NASA Technical Reports Server (NTRS)

    Cavage, William M.; Kuhlman, John M.

    1993-01-01

    An experimental study was conducted of the impingement of a single circular jet on a ground plane in a cross flow. This geometry is a simplified model of the interaction of propulsive jet exhaust from a V/STOL aircraft with the ground in forward flight. Jets were oriented normal to the cross flow and ground plane. Jet size, cross flow-to-jet velocity ratio, ground plane-to-jet board spacing, and jet exit turbulence level and mean velocity profile shape were all varied to determine their effects on the size of the ground vortex interaction region which forms on the ground plane, using smoke injection into the jet. Three component laser Doppler velocimeter measurements were made with a commercial three color system for the case of a uniform jet with exit spacing equal to 5.5 diameters and cross flow-to-jet velocity ratio equal to 0.11. The flow visualization data compared well for equivalent runs of the same nondimensional jet exit spacing and the same velocity ratio for different diameter nozzles, except at very low velocity ratios and for the larger nozzle, where tunnel blockage became significant. Variation of observed ground vortex size with cross flow-to-jet velocity ratio was consistent with previous studies. Observed effects of jet size and ground plane-to-jet board spacing were relatively small. Jet exit turbulence level effects were also small. However, an annular jet with a low velocity central core was found to have a significantly smaller ground vortex than an equivalent uniform jet at the same values of cross flow-to-jet velocity ratio and jet exit-to-ground plane spacing. This may suggest a means of altering ground vortex behavior somewhat, and points out the importance of proper simulation of jet exit velocity conditions. LV data indicated unsteady turbulence levels in the ground vortex in excess of 70 percent.

  16. Scalable and reusable emulator for evaluating the performance of SS7 networks

    NASA Astrophysics Data System (ADS)

    Lazar, Aurel A.; Tseng, Kent H.; Lim, Koon Seng; Choe, Winston

    1994-04-01

    A scalable and reusable emulator was designed and implemented for studying the behavior of SS7 networks. The emulator design was largely based on public domain software. It was developed on top of an environment supported by PVM, the Parallel Virtual Machine, and managed by OSIMIS-the OSI Management Information Service platform. The emulator runs on top of a commercially available ATM LAN interconnecting engineering workstations. As a case study for evaluating the emulator, the behavior of the Singapore National SS7 Network under fault and unbalanced loading conditions was investigated.

  17. The Stability of Radiatively Cooling Jets. 2: Nonlinear Evolution

    NASA Technical Reports Server (NTRS)

    Stone, James M.; Xu, Jianjun; Hardee, Philip

    1997-01-01

    modes that produce internal shocks and only small-amplitude wiggles within the jet. The fact that most observed systems show no evidence for large-amplitude sinusoidal oscillation leading to disruption is indicative that the perturbation frequencies are generally large, consistent with the suggestion that pro- tostellar jets arise from the inner regions (r less than 1 AU) of accretion disks.

  18. CYTOGENETIC STUDIES IN MICE TREATED WITH THE JET FUELS, JET-A AND JP-8

    EPA Science Inventory

    Cytogenetic studies in mice treated with the jet fuels, Jet-A and JP-8
    Abstract
    The genotoxic potential of the jet fuels, Jet-A and JP-8, were examined in mice treated on the skin with a single dose of 240 ug/mouse. Peripheral blood smears were prepared at the start of the ...

  19. Investigations of needle-free jet injections.

    PubMed

    Schramm-Baxter, J R; Mitragotri, S

    2004-01-01

    Jet injection is a needle-free drug delivery method in which a high-speed stream of fluid impacts the skin and delivers drugs. Although a number of jet injectors are commercially available, especially for insulin delivery, they have a low market share compared to needles possibly due to occasional pain associated with jet injection. Jets employed by the traditional jet injectors penetrate deep into the dermal and sub-dermal regions where the nerve endings are abundantly located. To eliminate the pain associated with jet injections, we propose to utilize microjets that penetrate only into the superficial region of the skin. However, the choice of appropriate jet parameters for this purpose is challenging owing to the multiplicity of factors that determine the penetration depth. Here, we describe the dependence of jet injections into human skin on the power of the jet. Dermal delivery of liquid jets was quantified using two measurements, penetration of a radiolabeled solute, mannitol, into skin and the shape of jet dispersion in the skin which was visualized using sulforhodamine B. The dependence of the amount of liquid delivered in the skin and the geometric measurements of jet dispersion on nozzle diameter and jet velocity was captured by a single parameter, jet power.

  20. The outer-membrane export signal of Porphyromonas gingivalis type IX secretion system (T9SS) is a conserved C-terminal β-sandwich domain

    PubMed Central

    de Diego, Iñaki; Ksiazek, Miroslaw; Mizgalska, Danuta; Koneru, Lahari; Golik, Przemyslaw; Szmigielski, Borys; Nowak, Magdalena; Nowakowska, Zuzanna; Potempa, Barbara; Houston, John A.; Enghild, Jan J.; Thøgersen, Ida B.; Gao, Jinlong; Kwan, Ann H.; Trewhella, Jill; Dubin, Grzegorz; Gomis-Rüth, F. Xavier; Nguyen, Ky-Anh; Potempa, Jan

    2016-01-01

    In the recently characterized Type IX Secretion System (T9SS), the conserved C-terminal domain (CTD) in secreted proteins functions as an outer membrane translocation signal for export of virulence factors to the cell surface in the Gram-negative Bacteroidetes phylum. In the periodontal pathogen Porphyromonas gingivalis, the CTD is cleaved off by PorU sortase in a sequence-independent manner, and anionic lipopolysaccharide (A-LPS) is attached to many translocated proteins, thus anchoring them to the bacterial surface. Here, we solved the atomic structure of the CTD of gingipain B (RgpB) from P. gingivalis, alone and together with a preceding immunoglobulin-superfamily domain (IgSF). The CTD was found to possess a typical Ig-like fold encompassing seven antiparallel β-strands organized in two β-sheets, packed into a β-sandwich structure that can spontaneously dimerise through C-terminal strand swapping. Small angle X-ray scattering (SAXS) revealed no fixed orientation of the CTD with respect to the IgSF. By introducing insertion or substitution of residues within the inter-domain linker in the native protein, we were able to show that despite the region being unstructured, it nevertheless is resistant to general proteolysis. These data suggest structural motifs located in the two adjacent Ig-like domains dictate the processing of CTDs by the T9SS secretion pathway. PMID:27005013