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Sample records for jian wang yuhong

  1. Identification of housekeeping genes suitable for gene expression analysis in Jian carp (Cyprinus carpio var. jian).

    PubMed

    Tang, Yong-kai; Yu, Ju-hua; Xu, Pao; Li, Jian-lin; Li, Hong-xia; Ren, Hong-tao

    2012-10-01

    Jian carp (Cyprinus carpio var. jian) is an important economic fish species cultured in China. In this report, we performed a systematic analysis to identify an appropriate housekeeping (HK) gene for the study of gene expression in Jian carp. For this purpose, partial DNA sequences of four potential candidate genes (elongation factor 1 alpha (EF-1α), glyceraldehyde-3-phosphate (GAPDH), beta-actin (ACTB), and 18S ribosomal RNA (18S rRNA) were isolated, and their expression levels were studied using RNA extracted from nine tissues (forebrain, hypothalamus, liver, fore-intestine, hind-intestine, ovary, muscle, heart, kidney) in juvenile and adult Jian carp. Gene expression levels were quantified by quantitative real time RT-PCR (qRT-PCR), and expression stability was evaluated by comparing the coefficients of variation (CV) of the Ct values. The results showed that EF-1α was the most suitable HK gene in all tissues of juvenile and adult Jian carp. However, at distinct juvenile and adult developmental stages, there was not a single optimal gene for normalization of expression levels in all tissues. EF-1α was the most stable gene only in forebrain, hypothalamus, liver, heart, and kidney. These results provide data that can be expected to aid gene expression analysis in Jian carp research, but underline the importance of identifying the optimal HK gene for each new experimental paradigm.

  2. Editorial: Which Wei Wang?

    SciTech Connect

    Sprouse, Gene D.

    2007-12-01

    The APS journals receive manuscripts from scientists all over the world. For authors whose names cannot be expressed in Latin characters, their names in the byline must be transliterated, a process that is not necessarily bidirectionally unique. For example, the eight Chinese names all transliterate as Wei Wang. To remove some of the ambiguity arising from this unfortunate degeneracy of names, APS will allow some authors the option to include their names in their own language in parentheses after the transliterated name, such as Wei Wang. The option to present names in the article byline in this manner is an experiment initially offered to Chinese, Japanese, and Korean authors, whose names can be expressed in Unicode characters. An example of a Japanese name is Tadanori Minamisono and a Korean name is Chang Kee Jung. In the English text the given name precedes the family name, while the reverse is true for the characters. As we gain experience, we may be able to broaden this offer to other languages. Authors who wish to try this option will need to prepare their manuscripts by following the special instructions at http://authors.aps.org/names.html.

  3. Genetic mapping and QTL analysis for body weight in Jian carp ( Cyprinus carpio var. Jian) compared with mirror carp ( Cyprinus carpio L.)

    NASA Astrophysics Data System (ADS)

    Gu, Ying; Lu, Cuiyun; Zhang, Xiaofeng; Li, Chao; Yu, Juhua; Sun, Xiaowen

    2015-05-01

    We report the genetic linkage map of Jian carp ( Cyprinus carpio var. Jian). An F1 population comprising 94 Jian carp individuals was mapped using 254 microsatellite markers. The genetic map spanned 1 381.592 cM and comprised 44 linkage groups, with an average marker distance of 6.58 cM. We identified eight quantitative trait loci (QTLs) for body weight (BW) in seven linkage groups, explaining 12.6% to 17.3% of the phenotypic variance. Comparative mapping was performed between Jian carp and mirror carp ( Cyprinus carpio L.), which both have 50 chromosomes. One hundred and ninety-eight Jian carp marker loci were found in common with the mirror carp map, with 186 (93.94%) showing synteny. All 44 Jian carp linkage groups could be one-to-one aligned to the 44 mirror carp linkage groups, mostly sharing two or more common loci. Three QTLs for BW in Jian carp were conserved in mirror carp. QTL comparison suggested that the QTL confidence interval in mirror carp was more precise than the homologous interval in Jian carp, which was contained within the QTL interval in Jian carp. The syntenic relationship and consensus QTLs between the two varieties provide a foundation for genomic research and genetic breeding in common carp.

  4. Threonine Affects Intestinal Function, Protein Synthesis and Gene Expression of TOR in Jian Carp (Cyprinus carpio var. Jian)

    PubMed Central

    Feng, Lin; Peng, Yan; Wu, Pei; Hu, Kai; Jiang, Wei-Dan; Liu, Yang; Jiang, Jun; Li, Shu-Hong; Zhou, Xiao-Qiu

    2013-01-01

    This study aimed to investigate the effects of threonine (Thr) on the digestive and absorptive ability, proliferation and differentiation of enterocytes, and gene expression of juvenile Jian carp (Cyprinus carpio var. Jian). First, seven isonitrogenous diets containing graded levels of Thr (7.4–25.2 g/kg diet) were fed to the fishes for 60 days. Second, enterocyte proliferation and differentiation were assayed by culturing enterocytes with graded levels of Thr (0–275 mg/l) in vitro. Finally, enterocytes were cultured with 0 and 205 mg/l Thr to determine protein synthesis. The percent weight gain (PWG), specific growth rate, feed intake, feed efficiency, protein retention value, activities of trypsin, lipase and amylase, weights and protein contents of hepatopancreas and intestine, folds heights, activities of alkaline phosphatase (AKP), γ- glutamyl transpeptidase and Na+/K+-ATPase in all intestinal segments, glutamate-oxaloacetate transaminase (GOT) and glutamate-pyruvate transaminase (GPT) activities in hepatopancreas, and 4E-BP2 gene expression in muscle, hepatopancreas and intestinal segments were significantly enhanced by Thr (p<0.05). However, the plasma ammonia concentration and TOR gene expression decreased (p<0.05). In vitro, Thr supplement significantly increased cell numbers, protein content, the activities of GOT, GPT, AKP and Na+/K+-ATPase, and protein synthesis rate of enterocytes, and decreased LDH activity and ammonia content in cell medium (p<0.05). In conclusion, Thr improved growth, digestive and absorptive capacity, enterocyte proliferation and differentiation, and protein synthesis and regulated TOR and 4E-BP2 gene expression in juvenile Jian carp. The dietary Thr requirement of juvenile Jian carp was 16.25 g/kg diet (51.3 g/kg protein) based on quadratic regression analysis of PWG. PMID:23922879

  5. Identification and characterization of a LTR retrotransposon from the genome of Cyprinus carpio var. Jian.

    PubMed

    Cao, Liping; Yin, Guojun; Cao, Zheming; Bing, Xuwen; Ding, Weidong

    2016-06-01

    A Ty3/gypsy-retrotransposon-type transposon was found in the genome of the Jian carp (Cyprinus carpio var. Jian) in a previous study (unpublished), and was designated a JRE retrotransposon (Jian retrotransposon). The full-length JRE retrotransposon is 5126 bp, which includes two long terminal repeats of 470 bp at the 5' end and 453 bp at the 3' end, and two open reading frames between them: 4203 bp encoding the group-specific antigen (GAG) and polyprotein (POL). The pol gene has a typical Ty3/gypsy retrotransposon structure, and the gene order is protease, reverse transcriptase, RNase H, and integrase (PR-RT-RH-IN). A phylogenetic analysis of the pol gene showed that it has similarities of 40.7, 40, and 32.8 %, to retrotransposons of Azumapecten farreri, Mizuhopecten yessoensis, and Xiphophorus maculatus, respectively. Therefore, JRE might belong to the JULE retrotransposon family. The copy number of the JRE transposon in the genome of the Jian carp is 124, determined with real-time quantitative PCR. The mRNA of the JRE retrotransposon is expressed in five Jian carp tissues, the liver, kidney, blood, muscle, and gonad, and slightly higher in the kidney and liver than in the other tissues.

  6. Generalized Sagnac-Wang-Fizeau formula

    NASA Astrophysics Data System (ADS)

    Ori, A.; Avron, J. E.

    2016-12-01

    We present a special-relativistic analysis of deformable interferometers where counterpropagating beams share a common optical path. The optical path is allowed to change rather arbitrarily and need not be stationary. We show that the phase shift has two contributions: One contribution is independent of the refractive index n and has the form of a line integral. This term gives the Wang empirical formula for deformable Sagnac interferometers. The second term is quadratic in n and has the form of a double integral. The analysis provides a unifying framework incorporating the Sagnac, Wang, and Fizeau effects in a single scheme, gives a rigorous proof of Wang empirical formula, and can be used to study various perturbations of Sagnac interferometers.

  7. Effect of dietary isoleucine on the immunity, antioxidant status, tight junctions and microflora in the intestine of juvenile Jian carp (Cyprinus carpio var. Jian).

    PubMed

    Zhao, Juan; Feng, Lin; Liu, Yang; Jiang, Weidan; Wu, Pei; Jiang, Jun; Zhang, Yongan; Zhou, Xiaoqiu

    2014-12-01

    This study was conducted to investigate the effects of dietary isoleucine (Ile) on the immune response, antioxidant status, tight junctions, and microbial population in the intestine of juvenile Jian carp (Cyprinus carpio var. Jian). A total of 1200 juvenile Jian carp with average initial weight 6.9 ± 0.03 g were fed semi-purified isonitrogenous diets containing 4.2 (unsupplemented control group), 7.0, 9.5, 11.9, 13.9 and 16.9 g Ile kg(-1) diet for 60 days. Results indicated that Ile supplementation decreased malondialdehyde (MDA) and protein carbonyl content, and the amounts of Escherichia coli and Aeromonas in the intestine (P < 0.05), and increased the activities of superoxide dismutase (SOD), catalase (CAT), and glutathione reductase (GR), glutathione content and the amounts of Lactobacillus and Bacillus in the intestine (P < 0.05). Furthermore, real time polymerase chain reaction revealed that relative mRNA expression of copper/zinc superoxide dismutase (Cu-ZnSOD), manganese superoxide dismutase (MnSOD), CAT, NF-E2-related factor 2 (Nrf2), p38 mitogen-activated protein kinases (p38MAPK) in the intestine were increased with increasing of dietary Ile up to a certain point (P < 0.05). Conversely, the relative mRNA expression of occludin, claudin-3, claudin-7, TNF-α, IL-10, Kelch-like-ECH- associated protein 1 (Keap1), extracellular signal-regulated kinase 1 (ERK1) in the intestine showed a downward trend (P < 0.05). In conclusion, dietary Ile improves intestinal immune function, antioxidant capacity and microbial population, and regulates gene expression of antioxidant enzyme, tight junctions, Nrf2, Keap1, p38 and ERK1 in the intestine of Jian carp.

  8. Wang-Landau integration --- The application of Wang-Landau sampling in numerical integration

    NASA Astrophysics Data System (ADS)

    Li, Ying Wai; Wuest, Thomas; Landau, David P.; Qing Lin, Hai

    2007-03-01

    Wang-Landau sampling was first introduced to simulate the density of states in energy space for various physical systems. This technique can be extended to numerical integrations due to certain similarities in nature of these two problems. It can be further applied to study quantum many-body systems. We report the feasibility of this application by discussing the correspondence between Wang-Landau integration and Wang-Landau sampling for Ising model. Numerical results for 1D and 2D integrations are shown. In particular, the utilization of this algorithm in the periodic lattice Anderson model is discussed as an illustrative example.

  9. A Study of 2,3,7,8-Tetrachlorodibenzo-p-dioxin Induced Liver Injury in Jian Carp (Cyprinus carpio var. Jian) Using Precision-Cut Liver Slices.

    PubMed

    Du, Jin-Liang; Cao, Li-Ping; Liu, Ying-Juan; Jia, Rui; Yin, Guo-Jun

    2016-01-01

    The aim of this study was to establish a model for the study of liver injury induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in Jian carp using precision-cut liver slices (PCLS). PCLS were treated with TCDD at concentrations of 0, 0.05, 0.1, 0.3, and 0.6 μg/L for 6 h, followed by collection of the culture supernatant and PCLS for analysis. Several biochemical indices were analyzed, including glutamic pyruvic transaminase (GPT), glutamic oxaloacetic transaminase (GOT), lactate dehydrogenase (LDH), superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), and malondialdehyde (MDA). Expression of mRNA was also estimated for cytochrome P4501A (CYP1A), aryl hydrocarbon receptor2 (AhR2), and aryl hydrocarbon receptor nuclear translocator2 (ARNT2). Results showed that some significant effects (p < 0.05) in MDA, GSH-Px and PCLS viability were observed at a TCDD concentration as low as 0.05 µg/L, and the observed effects increased with exposure concentration. Following exposure to TCDD for 6 h at a concentration of 0.3 μg/L, significant increases (p < 0.01) in the content of GPT, GOT, MDA, and LDH were observed, while SOD activity, GSH-Px activity, and PCLS viability were decreased (p < 0.01 or p < 0.05). Exposure to 0.3 μg/L TCDD also resulted in increased expression of mRNA for CYP1A, AhR2, and ARNT2. Overall, these results provide evidence of TCDD-induced liver injury and oxidative stress in Jian carp. These results also support the use of PCLS as an in vitro model for the evaluation of hepatotoxicity in Jian carp.

  10. Critical endpoint behavior: A Wang Landau study

    NASA Astrophysics Data System (ADS)

    Landau, D. P.; Wang, Fugao; Tsai, Shan-Ho

    2008-07-01

    We study the critical endpoint behavior using an asymmetric Ising model with two- and three-body interactions on a triangular lattice, in the presence of an external field. The simulation method we use is Wang-Landau sampling in a two-dimensional parameter space. We observe a clear divergence of the curvature of the spectator phase boundary and of the magnetization coexistence diameter derivative at the critical endpoint, and the exponents for both divergences agree well with previous theoretical predictions.

  11. Magnitude of the Wang-Landau error

    NASA Astrophysics Data System (ADS)

    Brown, Gregory; Rikvold, PA; Odbadrakh, Kh; Nicholson, DM

    2016-09-01

    The Wang-Landau algorithm is an entropic sampling method that incoroporates an update factor ln fi , which introduces a self-avoidance tendency into the random walk. Continued sampling at constant ln fi leads to a steady state estimate of the density of states ln gi (E). We find numerically that the difference between ln gi (E) and the true density of states ln g (E) is proportional to the update factor.

  12. Numerical integration using Wang Landau sampling

    NASA Astrophysics Data System (ADS)

    Li, Y. W.; Wüst, T.; Landau, D. P.; Lin, H. Q.

    2007-09-01

    We report a new application of Wang-Landau sampling to numerical integration that is straightforward to implement. It is applicable to a wide variety of integrals without restrictions and is readily generalized to higher-dimensional problems. The feasibility of the method results from a reinterpretation of the density of states in statistical physics to an appropriate measure for numerical integration. The properties of this algorithm as a new kind of Monte Carlo integration scheme are investigated with some simple integrals, and a potential application of the method is illustrated by the evaluation of integrals arising in perturbation theory of quantum many-body systems.

  13. Wang-Landau sampling for homopolymer collapse

    NASA Astrophysics Data System (ADS)

    Seaton, Daniel T.; Mitchell, Steven J.; Landau, David P.

    2008-03-01

    We explore the behavior of a continuum-homopolymer model using the Wang-Landau algorithm, concentrating on phase transitions such as the coil-globule and solid-liquid transitions. Using the density of states generated by the Wang-Landau algorithm, we calculate various thermodynamic quantities, e.g., the internal energy and specific heat. We also study how algorithmic parameters, such as sampling boundaries (maximum and minimum energies for random walks) and the final value of the modification factor, affect these quantities. In particular, we observe how the sampling boundaries can significantly alter the transition behavior. Our results are compared with two recent studies that yielded contradictory results, one using the bond-fluctuation model and the other using a continuum model similar to our own. We find that the transitions seen in our model are much more similar to those in the bond-fluctuation study. The careful analysis of the effects of algorithmic parameters on thermodynamic quantities should be relevant to the study of other polymeric/protein models.

  14. Ca(2+) and caspases are involved in hydroxyl radical-induced apoptosis in erythrocytes of Jian carp (Cyprinus carpio var. Jian).

    PubMed

    Li, HuaTao; Feng, Lin; Jiang, WeiDan; Liu, Yang; Jiang, Jun; Zhang, YongAn; Wu, Pei; Zhou, XiaoQiu

    2015-10-01

    There are young erythrocytes and mature erythrocytes in the peripheral blood of fish. The present study explored the apoptosis in hydroxyl radical ((·)OH)-induced young and mature erythrocytes of Jian carp (Cyprinus carpio var. Jian). Carp erythrocytes from the peripheral blood were separated into the young fraction, the intermediate fraction and the mature fraction using fixed-angle centrifugation. The erythrocytes in three age fractions were treated with the caspase inhibitors (zVAD-fmk) in physiological carp saline (PCS) or Ca(2+)-free PCS in the presence of 40 μM FeSO4/20 μM H2O2. The results showed that the (·)OH-induced reactive oxygen species (ROS) generation, phosphatidylserine (PS) exposure and DNA fragmentation are caspase dependent in carp erythrocytes. Furthermore, the ROS generation, PS exposure and DNA fragmentation in the more young fraction are more dependent on the caspase activity. This suggested that the caspases are involved in the (·)OH-induced apoptosis in the young erythrocytes of fish. Results also indicated that Ca(2+) is involved in (·)OH-induced calpain activation, PS exposure and DNA fragmentation in carp erythrocytes. Moreover, the calpain activation, DNA fragmentation and PS exposure in the more mature fraction are more dependent on the levels of Ca(2+). This revealed that (·)OH-induced apoptosis is Ca(2+) dependent in the mature erythrocytes of fish. Taken together, there might be two apoptosis pathways in fish erythrocytes: one is the caspase-dependent apoptosis in the young erythrocytes and the other is the Ca(2+)-involved apoptosis in the mature erythrocytes.

  15. Effect of dietary arginine on growth, intestinal enzyme activities and gene expression in muscle, hepatopancreas and intestine of juvenile Jian carp (Cyprinus carpio var. Jian).

    PubMed

    Chen, Gangfu; Feng, Lin; Kuang, Shengyao; Liu, Yang; Jiang, Jun; Hu, Kai; Jiang, Weidan; Li, Shuhong; Tang, Ling; Zhou, Xiaoqiu

    2012-07-01

    The present study was conducted to test the hypothesis that dietary arginine promotes digestion and absorption capacity, and, thus, enhances fish growth. This improvement might be related to the target of rapamycin (TOR) and eIF4E-binding protein (4E-BP). A total of 1200 juvenile Jian carp, Cyprinus carpio var. Jian, with an average initial weight of 6.33 (SE 0.03) g, were fed with diets containing graded concentrations of arginine, namely, 9.8 (control), 12.7, 16.1, 18.5, 21.9 and 24.5 g arginine/kg diet for 9 weeks. An real-time quantitative PCR analysis was performed to determine the relative expression of TOR and 4E-BP in fish muscle, hepatopancreas and intestine. Dietary arginine increased (P < 0.05): (1) glutamate-oxaloacetate transaminase and glutamate-pyruvate transaminase activities in muscle and hepatopancreas; (2) intestine and hepatopancreas protein content, folds height, and trypsin, chymotrypsin, lipase, Na⁺/K⁺-ATPase, alkaline phosphatase, γ-glutamyl transpeptidase and creatine kinase activities in intestine; (3) Lactobacillus counts; (4) relative expression of TOR in the muscle, hepatopancreas and distal intestine (DI); (5) relative expression of 4E-BP in proximal intestine (PI) and mid-intestine (MI), as compared with the control group. In contrast, dietary arginine reduced (P < 0.05): (1) plasma ammonia content; (2) Aeromonas hydrophila and Escherichia coli counts; (3) relative expression of TOR in PI and MI; (4) relative expression of 4E-BP in the muscle, hepatopancreas and DI. The arginine requirement estimated by specific growth rate using quadratic regression analysis was found to be 18.0 g/kg diet. These results indicate that arginine improved fish growth, digestive and absorptive ability and regulated the expression of TOR and 4E-BP genes.

  16. [Lin Xue-Jian's experience on treatment of a part of cerebral diseases with scalp acupuncture].

    PubMed

    Wang, Hai-Li; Wu, Jiu-Wei

    2005-10-01

    LIN Xue-Jian adopts Chinese traditional acupuncture and moxibustion manipulation methods to stimulate the special area of scalp to treat a part of brain-derived diseases, such as infantile cerebral palsy, nerve deafness, cerebellar ataxia, lacunar cerebral infarction, senile dementia, Parkinson's disease, anxiety, insomnia and central constipation, and so on. Scalp acupuncture can improve ability of blood and oxygen supply for general blood vessels; stimulation of corresponding acupoint area according to symptoms and signs can control condition of disease; and can repair, activate and regenerate the injured, dormancy and aging neurons, so as to dredge nerve network in the brain, hence better therapeutic effect.

  17. [Japanese monograph of dietary Chinese materia medica: Ben chao shi jian].

    PubMed

    Zhou, Min

    2009-01-01

    Ben chao shi jian was a monograph of dietary Chinese materia medica written by Japanese doctor: [see text], following the style of Ben cao gang mu (Compendium of Materia Medica). The book consulted Ben cao gang mu and associated with the actual situation of Japan, making elaborate illustrations on the function, toxicity, form feature, manufacture and collection of 442 kinds of dietary Chinese material medica produced from Japan and combining organically with all kinds of knowledges including medicice and pharmacology, health preservation, nutriology and gastrology etc. It was a very important work in the developmental history of dietology and medicative dietology in Japan with high practical and academic values.

  18. County town -- jian-zhi town differentials and migration to towns in China.

    PubMed

    Ma, R

    1993-07-01

    China's urbanization process is unique in having been due to economic systems and migration policies. Towns and townships in rural areas are different from cities in their social and economic characteristics and their structure and function. The urban system in China is initially described with the distinction drawn between cities, "jian-zhi towns", (organic town) which are officially recognized, and rural areas. Analysis is provided f the economic and residential registration status of town residents and migration in northern China. Data were obtained from a 1987 survey of 1314 households in Wongnioute Banner in Inner Mongolia, and a 1985 migration survey of 2089 rural households in 41 villages. The study area was selected because jian-zhi town status was easily obtained and the are needed more towns for local administration and trade; the area was similar in geographic, social, economic, and cultural characteristics to other northern and northwestern regions. The Wongnioute Banner comprises 5 towns (Qiaotou, Wufendi, Hairesu, Wuduentaohai, and Wutonghua) and 1 country town (Wudan). All citizens from birth have an agricultural or nonagricultural status, which can be changed by passing national exams or completing a university education, joining the military and becoming an officer, marrying someone with a nonagricultural status, reunifying the family, or holding a special program. Quotas are set annually for status changes, e.g. in Tibet Autonomous Region the annual quota was 3%. Town residents may have either status. In the sample, 56.6% lived in town and had a nonagricultural status; 17.7% of heads of household town residents had an agricultural status and had stronger ties to villages because of family connections. Commuters are a third group and comprise 8.9%. County towns and jian-zhi towns are grouped the same, but are quite different in population size. Wudan had a population of 27,600 spread over an area of 480 hectares. The jian-zhi towns each had an

  19. Cultivating a "Jian Zi": Exploring an Art Teacher's Responsive Pedagogy for the Development of Art Talent in Taiwan

    ERIC Educational Resources Information Center

    Chen, Wei-Ren

    2017-01-01

    This qualitative case study explored the operational curricula of an art teacher's responsive pedagogy that focused on the differentiation aspects for artistically talented students in an elementary school in Taiwan. Findings indicate that cultivating a "Jian Zi" is the heart of the value system embedded in the art teacher's responsive…

  20. The Wang-Landau Sampling Algorithm

    NASA Astrophysics Data System (ADS)

    Landau, David P.

    2003-03-01

    Over the past several decades Monte Carlo simulations[1] have evolved into a powerful tool for the study of wide-ranging problems in statistical/condensed matter physics. Standard methods sample the probability distribution for the states of the system, usually in the canonical ensemble, and enormous improvements have been made in performance through the implementation of novel algorithms. Nonetheless, difficulties arise near phase transitions, either due to critical slowing down near 2nd order transitions or to metastability near 1st order transitions, thus limiting the applicability of the method. We shall describe a new and different Monte Carlo approach [2] that uses a random walk in energy space to determine the density of states directly. Once the density of states is estimated, all thermodynamic properties can be calculated at all temperatures. This approach can be extended to multi-dimensional parameter spaces and has already found use in classical models of interacting particles including systems with complex energy landscapes, e.g., spin glasses, protein folding models, etc., as well as for quantum models. 1. A Guide to Monte Carlo Simulations in Statistical Physics, D. P. Landau and K. Binder (Cambridge U. Press, Cambridge, 2000). 2. Fugao Wang and D. P. Landau, Phys. Rev. Lett. 86, 2050 (2001); Phys. Rev. E64, 056101-1 (2001).

  1. The role of Wang-Landau sampling in materials development

    NASA Astrophysics Data System (ADS)

    Landau, David

    2012-02-01

    An understanding of the thermodynamic behavior of materials as well as the prediction of the properties of ``materials by design'' often depends upon knowledge of the free energy of the system under study. Computer simulations offer a powerful tool for such investigations, but traditional methods often suffer from long time scales and metastable states due to the roughness of the free energy landscape. Wang-Landau samplingootnotetextF. Wang and D. P. Landau, Phys. Rev. Lett. 86, 2050 (2001); F. Wang and D. P. Landau, Phys. Rev. E 64, 05610 (2001). is a powerful alternative to traditional Monte Carlo algorithms which can alleviate many such problems. We will review the Wang-Landau algorithm and discuss various implementations as well as possible application to materials development.

  2. Avoiding boundary effects in Wang-Landau sampling

    NASA Astrophysics Data System (ADS)

    Schulz, B. J.; Binder, K.; Müller, M.; Landau, D. P.

    2003-06-01

    A simple modification of the “Wang-Landau sampling” algorithm removes the systematic error that occurs at the boundary of the range of energy over which the random walk takes place in the original algorithm.

  3. [Study of dates of birth and death of WANG Tao].

    PubMed

    Song, Zhen-Min

    2011-03-01

    The dates of birth and death of WANG Tao, a famous doctor in Tang dynasty, are not found in literature and scholars have different points upon this subject. It could be sure that WANG Tao was appointed mayor of Huayuan county in the ninth year of Kaiyuan period (721) and in December of the fourteenth year of Tianbao period (756) he the revolt in Hejian. The recording after 756 could not be found in literature. According to the official system in Tang dynasty that officers retired at their age of 70, it could be sure that WANG Tao was less than 70 year old in 756. Considering his age when he was the county mayor in 721, it could be speculated that WANG Tao was born during the third year of Chuigong period (687) to the second year of Changshou period (693), and his death date should be some date after 756. But it couldn't be validated.

  4. Massively parallel Wang-Landau sampling on multiple GPUs

    NASA Astrophysics Data System (ADS)

    Yin, Junqi; Landau, D. P.

    2012-08-01

    Wang-Landau sampling is implemented on the Graphics Processing Unit (GPU) with the Compute Unified Device Architecture (CUDA). Performances on three different GPU cards, including the new generation Fermi architecture card, are compared with that on a Central Processing Unit (CPU). The parameters for massively parallel Wang-Landau sampling are tuned in order to achieve fast convergence. For simulations of the water cluster systems, we obtain an average of over 50 times speedup for a given workload.

  5. Massively parallel Wang Landau sampling on multiple GPUs

    SciTech Connect

    Yin, Junqi; Landau, D. P.

    2012-01-01

    Wang Landau sampling is implemented on the Graphics Processing Unit (GPU) with the Compute Unified Device Architecture (CUDA). Performances on three different GPU cards, including the new generation Fermi architecture card, are compared with that on a Central Processing Unit (CPU). The parameters for massively parallel Wang Landau sampling are tuned in order to achieve fast convergence. For simulations of the water cluster systems, we obtain an average of over 50 times speedup for a given workload.

  6. Chemical gas-dynamics beyond Wang Chang-Uhlenbeck's kinetics

    SciTech Connect

    Kolesnichenko, Evgeniy G.; Gorbachev, Yuriy E.

    2014-12-09

    Wang Chang-Uhlenbeck equation does not give possibility to take into account intermolecular processes such as redistribution of the energy among different degrees of freedom. The modification of the generalized Wang Chang-Uhlenbeck equation including such processes is proposed. It allows to study for instance the kinetics of non-radiative transitions. Limitations of this approach are connected with the requirements of absence of polarization of rotational momentum and phases of intermolecular vibrations.

  7. Chemical gas-dynamics beyond Wang Chang-Uhlenbeck's kinetics

    NASA Astrophysics Data System (ADS)

    Kolesnichenko, Evgeniy G.; Gorbachev, Yuriy E.

    2014-12-01

    Wang Chang-Uhlenbeck equation does not give possibility to take into account intermolecular processes such as redistribution of the energy among different degrees of freedom. The modification of the generalized Wang Chang-Uhlenbeck equation including such processes is proposed. It allows to study for instance the kinetics of non-radiative transitions. Limitations of this approach are connected with the requirements of absence of polarization of rotational momentum and phases of intermolecular vibrations.

  8. Dietary choline modulates immune responses, and gene expressions of TOR and eIF4E-binding protein2 in immune organs of juvenile Jian carp (Cyprinus carpio var. Jian).

    PubMed

    Wu, Pei; Jiang, Jun; Liu, Yang; Hu, Kai; Jiang, Wei-Dan; Li, Shu-Hong; Feng, Lin; Zhou, Xiao-Qiu

    2013-09-01

    The present work evaluates the effects of various levels of dietary choline on immune parameters, immune-related gene expression and protection against Aeromonas hydrophila (AH) in juvenile Jian carp (Cyprinus carpio var. Jian). Fish were fed with six different experimental diets containing graded levels of choline at 165 (choline-deficient control), 310, 607, 896, 1167 and 1820 mg kg(-1) diet for 65 days. At the end of the feeding trail, Fish were challenged with AH and mortalities were recorded over 17 days. Dietary choline significantly enhanced spleen and head kidney weights, spleen index, red blood cell and white blood cell counts, and intestinal Lactobacillus counts of juvenile Jian carp; whereas, intestinal Escherichia coli and A. hydrophila counts decreased. Moreover, the post-challenge survival rate, leucocyte phagocytic capacity, serum lysozyme and acid phosphatase activities, hemagglutination titer, complement 3 and 4 contents, immunoglobulin M content, and anti-AH antibody titer were significantly enhanced by choline and the lowest in choline-deficient group, while serum total iron-binding capacity was the highest in choline-deficient group. The relative gene expressions of interleukin 10 in spleen and head kidney, target of rapamycin (TOR) in spleen and eIF4E-binding protein2 (4E-BP2) in head kidney significantly increased with increasing of dietary choline up to a certain point. However, the relative gene expressions of interleukin 1β, tumor necrosis factor α and transforming growth factor β2 in spleen and head kidney, TOR in head kidney and 4E-BP2 in spleen significantly decreased. In conclusion, dietary choline improved disease resistance, enhanced the immune function, and regulated immune-related gene expression of juvenile Jian carp.

  9. Convergence and refinement of the Wang Landau algorithm

    NASA Astrophysics Data System (ADS)

    Lee, Hwee Kuan; Okabe, Yutaka; Landau, D. P.

    2006-07-01

    Recently, Wang and Landau proposed a new random walk algorithm that can be very efficiently applied to many problems. Subsequently, there has been numerous studies on the algorithm itself and many proposals for improvements were put forward. However, fundamental questions such as what determines the rate of convergence has not been answered. To understand the mechanism behind the Wang-Landau method, we did an error analysis and found that a steady state is reached where the fluctuations in the accumulated energy histogram saturate at values proportional to [. This value is closely related to the error corrections to the Wang-Landau method. We also study the rate of convergence using different "tuning" parameters in the algorithm.

  10. [Discussion on WANG Guo-rui's acupuncture academy thought].

    PubMed

    Gao, Xi-Yan; Wang, Xin; Gao, Ling; Chen, Xin-Wang

    2013-12-01

    Through study on Bianque Shenying Zhenjiu Yulong Jing (Bianque's Classic of Effective Acupuncture Prescriptions), acupuncture experiences and ideology of WANG Guo-rui, an acupuncture physician of the Yuan Dynasty (1271-1368), is discussed in this article. Inherited and carried forward DOU's acupuncture theory, WANG Guo-rui encouraged to use experiential points and to expand extra points. Penetrating needling method was created, and the application of acupoints according to needling opportunities and seasonal factors were enriched by him. Great importance was also attached on treatment according to differentiation of syndromes, which including the simultaneous acupuncture and moxibustion, simultaneous reinforcing and reducing, reducing after reinforcing, reinforcing after reducing, predomination of reducing and predomination of reinforcing. The flexible treating methods are still extensively adopted in clinic nowadays. WANG Guo-rui is a master of clinical acupuncture who made great contribution to the development of acupuncture and moxibustion.

  11. [The anatomical concept of Ma Wang Dui archeological artifacts].

    PubMed

    Yang, Su-Tso

    2010-01-01

    Amongst the archeological findings of Ma Wang Dui that concern the human anatomy, the first noted was a well-preserved female corpse, which demonstrated superb antiseptic techniques of the ancient Chinese. Also, 14 medical books were excavated and revealed a prototype of human visceral anatomy. The differentiation between small and large intestines was absent, and only the term of "intestine" was mentioned. The term of "triple energizers" was absent, too. However, contexts of surface anatomy were already abundant. Analyzing the terms of relative position, the anatomical position portrayed by the Ma Wang Dui medical texts is very similar to that of modern medicine.

  12. 76 FR 72387 - Order Relating to Xun Wang

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-23

    ... the Regulations. The purpose of the conspiracy was to bring about the export of epoxy paint and epoxy... Industry Huaxing Construction Co. Ltd. (``Huaxing''). The epoxy paint and thinner were designated as EAR99... supply Huaxing with U.S.-origin PPG epoxy paint and thinner. During this meeting, Wang and...

  13. Reclassification of Deinococcus xibeiensis Wang et al. 2010 as a heterotypic synonym of Deinococcus wulumuqiensis Wang et al. 2010.

    PubMed

    Hong, Sunhee; Farrance, Christine E; Russell, Anne; Yi, Hana

    2015-03-01

    Two species of the genus Deinococcus, namely Deinococcus wulumuqiensis Wang et al. 2010 and Deinococcus xibeiensis Wang et al. 2010, were simultaneously proposed and described in the same publication. However, the identical 16S rRNA gene sequence of the two type strains strongly raised the probability of their relatedness at the species level. Thus, the genomic relatedness of the two species of the genus Deinococcus was investigated here to clarify their taxonomic status. The high (99.9 %) average nucleotide identity (ANI) between the genome sequences of the two type strains suggested that the two species are synonymous. Additional phenotypic data including enzymic activities and substrate-utilization profiles showed no pronounced differences between the type strains of the two species. Data from this study demonstrated that the two taxa constitute a single species. According to Rule 42 of the Bacteriological Code, we propose that D. xibeiensis Wang et al. 2010 should be reclassified as a subjective heterotypic synonym of D. wulumuqiensis Wang et al. 2010.

  14. Effect of dietary glutamine on growth performance, non-specific immunity, expression of cytokine genes, phosphorylation of target of rapamycin (TOR), and anti-oxidative system in spleen and head kidney of Jian carp (Cyprinus carpio var. Jian).

    PubMed

    Hu, Kai; Zhang, Jing-Xiu; Feng, Lin; Jiang, Wei-Dan; Wu, Pei; Liu, Yang; Jiang, Jun; Zhou, Xiao-Qiu

    2015-06-01

    This study was designed to investigate the effects of dietary glutamine on the growth performance, cytokines, target of rapamycin (TOR), and antioxidant-related parameters in the spleen and head kidney of juvenile Jian carp (Cyprinus carpio var. Jian). Fish were fed the basal (control) and glutamine-supplemented (12.0 g glutamine kg(-1) diet) diets for 6 weeks. Results indicated that the dietary glutamine supplementation improved the growth performance, spleen protein content, serum complement 3 content, and lysozyme activity in fish. In the spleen, glutamine down-regulated the expression of the interleukin 1 and interleukin 10 genes, and increased the level of phosphorylation of TOR protein. In the head kidney, glutamine down-regulated the tumor necrosis factor α and interleukin 10 gene expressions, phosphorylated and total TOR protein levels, while up-regulated the transforming growth factor β2 gene expression. Furthermore, the protein carbonyl content was decreased in the spleen of fish fed glutamine-supplemented diet; conversely, the anti-hydroxyl radical capacity and glutathione content in the spleen were increased by glutamine. However, diet supplemented with glutamine did not affect the lipid peroxidation, anti-superoxide anion capacity, and antioxidant enzyme activities in the spleen. Moreover, all of these antioxidant parameters in the head kidney were not affected by glutamine. Results from the present experiment showed the importance of dietary supplementation of glutamine in benefaction of the growth performance and several components of the innate immune system, and the deferential role in cytokine gene expression, TOR kinase activity, and antioxidant status between the spleen and head kidney of juvenile Jian carp.

  15. Wang-Landau sampling with logarithmic windows for continuous models.

    PubMed

    Xie, Y L; Chu, P; Wang, Y L; Chen, J P; Yan, Z B; Liu, J-M

    2014-01-01

    We present a modified Wang-Landau sampling (MWLS) for continuous statistical models by partitioning the energy space into a set of windows with logarithmically shrinking width. To demonstrate its necessity and advantages, we apply this sampling to several continuous models, including the two-dimensional square XY spin model, triangular J1-J2 spin model, and Lennard-Jones cluster model. Given a finite number of bins for partitioning the energy space, the conventional Wang-Landau sampling may not generate sufficiently accurate density of states (DOS) around the energy boundaries. However, it is demonstrated that much more accurate DOS can be obtained by this MWLS, and thus a precise evaluation of the thermodynamic behaviors of the continuous models at extreme low temperature (kBT<0.1) becomes accessible. The present algorithm also allows efficient computation besides the highly reliable data sampling.

  16. Generic, hierarchical framework for massively parallel Wang-Landau sampling.

    PubMed

    Vogel, Thomas; Li, Ying Wai; Wüst, Thomas; Landau, David P

    2013-05-24

    We introduce a parallel Wang-Landau method based on the replica-exchange framework for Monte Carlo simulations. To demonstrate its advantages and general applicability for simulations of complex systems, we apply it to different spin models including spin glasses, the Ising model, and the Potts model, lattice protein adsorption, and the self-assembly process in amphiphilic solutions. Without loss of accuracy, the method gives significant speed-up and potentially scales up to petaflop machines.

  17. Generic, Hierarchical Framework for Massively Parallel Wang-Landau Sampling

    NASA Astrophysics Data System (ADS)

    Vogel, Thomas; Li, Ying Wai; Wüst, Thomas; Landau, David P.

    2013-05-01

    We introduce a parallel Wang-Landau method based on the replica-exchange framework for Monte Carlo simulations. To demonstrate its advantages and general applicability for simulations of complex systems, we apply it to different spin models including spin glasses, the Ising model, and the Potts model, lattice protein adsorption, and the self-assembly process in amphiphilic solutions. Without loss of accuracy, the method gives significant speed-up and potentially scales up to petaflop machines.

  18. A generic, hierarchical framework for massively parallel Wang Landau sampling

    SciTech Connect

    Vogel, Thomas; Li, Ying Wai; Wuest, Thomas; Landau, David P

    2013-01-01

    We introduce a parallel Wang Landau method based on the replica-exchange framework for Monte Carlo simulations. To demonstrate its advantages and general applicability for simulations of com- plex systems, we apply it to the self-assembly process in amphiphilic solutions and to lattice protein adsorption. Without loss of accuracy, the method gives significant speed-up on small architectures like multi-core processors, and should be beneficial for petaflop machines.

  19. Learning from the past: Rare ε-Fe2O3 in the ancient black-glazed Jian (Tenmoku) wares

    PubMed Central

    Dejoie, Catherine; Sciau, Philippe; Li, Weidong; Noé, Laure; Mehta, Apurva; Chen, Kai; Luo, Hongjie; Kunz, Martin; Tamura, Nobumichi; Liu, Zhi

    2014-01-01

    Ancient Jian wares are famous for their lustrous black glaze that exhibits unique colored patterns. Some striking examples include the brownish colored “Hare's Fur” (HF) strips and the silvery “Oil Spot” (OS) patterns. Herein, we investigated the glaze surface of HF and OS samples using a variety of characterization methods. Contrary to the commonly accepted theory, we identified the presence of ε-Fe2O3, a rare metastable polymorph of Fe2O3 with unique magnetic properties, in both HF and OS samples. We found that surface crystals of OS samples are up to several micrometers in size and exclusively made of ε-Fe2O3. Interestingly, these ε-Fe2O3 crystals on the OS sample surface are organized in a periodic two dimensional fashion. These results shed new lights on the actual mechanisms and kinetics of polymorphous transitions of Fe2O3. Deciphering technologies behind the fabrication of ancient Jian wares can thus potentially help researchers improve the ε-Fe2O3 synthesis. PMID:24820819

  20. Learning from the past: Rare ɛ-Fe2O3 in the ancient black-glazed Jian (Tenmoku) wares

    NASA Astrophysics Data System (ADS)

    Dejoie, Catherine; Sciau, Philippe; Li, Weidong; Noé, Laure; Mehta, Apurva; Chen, Kai; Luo, Hongjie; Kunz, Martin; Tamura, Nobumichi; Liu, Zhi

    2014-05-01

    Ancient Jian wares are famous for their lustrous black glaze that exhibits unique colored patterns. Some striking examples include the brownish colored ``Hare's Fur'' (HF) strips and the silvery ``Oil Spot'' (OS) patterns. Herein, we investigated the glaze surface of HF and OS samples using a variety of characterization methods. Contrary to the commonly accepted theory, we identified the presence of ɛ-Fe2O3, a rare metastable polymorph of Fe2O3 with unique magnetic properties, in both HF and OS samples. We found that surface crystals of OS samples are up to several micrometers in size and exclusively made of ɛ-Fe2O3. Interestingly, these ɛ-Fe2O3 crystals on the OS sample surface are organized in a periodic two dimensional fashion. These results shed new lights on the actual mechanisms and kinetics of polymorphous transitions of Fe2O3. Deciphering technologies behind the fabrication of ancient Jian wares can thus potentially help researchers improve the ɛ-Fe2O3 synthesis.

  1. Wang-Landau Simulations of Adsorbed and Confined Lattice Proteins

    NASA Astrophysics Data System (ADS)

    Pattanasiri, Busara; Li, Ying Wai; Landau, David P.; Wüst, Thomas

    2012-08-01

    The hydrophobic-polar (HP) model has emerged as one of the standard approaches for simulating protein folding. In this work, we used this model together with Wang-Landau (WL) sampling and appropriate Monte Carlo trial moves to determine the density of states and thermodynamics for two cases: Protein adsorption and protein confinement, in the vicinity of attractive surfaces. The influence on the adsorption behavior of surface attractive strength in the adsorption case and volumetric spaces in the confinement case will be discussed.

  2. Dynamics analysis of fractional order Yu-Wang system

    NASA Astrophysics Data System (ADS)

    Bhalekar, Sachin

    2013-10-01

    Fractional order version of a dynamical system introduced by Yu and Wang (Engineering, Technology & Applied Science Research, 2, (2012) 209-215) is discussed in this article. The basic dynamical properties of the system are studied. Minimum effective dimension 0.942329 for the existence of chaos in the proposed system is obtained using the analytical result. For chaos detection, we have calculated maximum Lyapunov exponents for various values of fractional order. Feedback control method is then used to control chaos in the system. Further, the system is synchronized with itself and with fractional order financial system using active control technique. Modified Adams-Bashforth-Moulton algorithm is used for numerical simulations.

  3. Convergence for the Wang-Landau density of states.

    PubMed

    Brown, G; Odbadrakh, Kh; Nicholson, D M; Eisenbach, M

    2011-12-01

    The Wang-Landau method of estimating the density of states g(E) has become a powerful tool in statistical mechanics. Here it is shown that the distribution of random walkers sampled using an estimated density of states can always be used to improve the estimate. Specifically, this can be done without resorting to an auxiliary modification factor f, which previously has been used to find g(E) self-consistently through a procedure that reduces f incrementally toward unity. This straightforward approach is validated for multiple, independent random walkers.

  4. [Clearing the doubts of all Wang Bing in the Tang dynasty].

    PubMed

    Qiao, H; Qiao, Y; Li, H

    1999-10-01

    The problem is probed on the clues provided by Si ku ti yao zheng (Analysis on Summary of Books in Four Parts). It is claimed that the Wang bing (*) recommended by Wei Kang and that recommended by Yuwen Rong in Yu Jiaxi's work refer to the same person, both are identical to the time of the author of Su wen. Further, the time of the above 2 Wang Bing(s) and the Wang Bing recorded in lie nu zhuan (Biongraphies of chaste women) as the son of Wang Lin, are also overlapped with the time of the author of Su wen. It is possible that they are the same person. However, the details of the Wang Bing mentioned in Lang guan shi zhu ti ming (inscription for Lang guan Stone Pillar) is unknown. Again, it is unlikely that the Wang Bing (*) is the author of Su wen and can be only a farfetched analogy drawn after Su Fu's poet.

  5. Anti-inflammatory and hepatoprotective effects of glycyrrhetinic acid on CCl4-induced damage in precision-cut liver slices from Jian carp (Cyprinus carpio var. jian) through inhibition of the nf-kƁ pathway.

    PubMed

    Cao, Liping; Ding, Weidong; Jia, Rui; Du, Jingliang; Wang, Tao; Zhang, Chunyun; Gu, Zhengyan; Yin, Guojun

    2017-03-10

    In order to evaluate the antioxidant and anti-inflammatory effects of glycyrrhetinic acid (GA) on carbon tetrachloride (CCl4)-induced damage in precision-cut liver slices (PCLS) from Jian carp (Cyprinus carpio. Jian), an acute liver damage model was established in this study. The viability of PCLS, levels of anti-oxidases in liver homogenates, expression of inflammation-related genes including nuclear factor-κB (nf-κB)/c-rel, inducible nitric oxide synthase (inos), interleukin-1β (il-1β), interleukin-6 (il-6) and interleukin-8 (il-8), and protein levels of (nf-κB)/c-rel in liver tissues were measured. The results showed that pretreatment of PCLS with GA at 5 and 10 μg/mL for 6 h significantly inhibited the cytotoxicity of CCl4. GA attenuated CCl4-induced oxidative stress in PCLS through promoting the recovery of superoxide dismutase (SOD) and glutathione (GSH) levels, and inhibiting malondialdehyde (MDA) synthesis. In inflammatory response, GA at both 5 and 10 μg/mL significantly inhibited the increase in mRNA levels of inflammatory cytokines including nf-kƁ/c-rel, inos, il-1β, il-6 and il-8, and the protein level of Nf-kƁ/C-rel induced by CCl4. Furthermore, treatment with pyrrolyl dithiocarbamate (PDTC, 4 μg/mL), an inhibitor of nuclear transcription factor nf-kB, significantly inhibited nf-kB levels, and transcription of downstream cytokines inos, il-1β, il-6 and il-8, also the viability of PCLS was significantly increased. These results indicated that GA suppressed inflammation and reduced cytotoxicity by inhibiting the nf-kƁ signaling pathway, and plays a role in liver protection.

  6. The Application of Survey in ER Wang Temple Restituting

    NASA Astrophysics Data System (ADS)

    Shuai, W.; Rong, Z.

    2013-07-01

    Er Wang Temple, in World Heritage Site "Dujiang Weirs and Qingchengshan Mountai", was severely destroyed in Wenchuan earthquake of May 2008. There are several problems at different level in every building, such as structural distortion, foundation displacement, wall fracture, roof damage, etc. The stage was completely collapsed in the earthquake. Tableland the stage situated had a huge crack and slope collapse. This article is for the stage renovation. The survey of damage in earthquake is the basis of Er Wang Temple restituting. Survey including field survey after the earthquake and the measurement and investigation for the remained construction member of the main wood structure. For field survey, the basis of pillars which had not have significantly affects in earthquake could be seem as the reference points for measurement. The investigation of remained main wood construction member, especially the size of the key structures and site and manufacture method of the joints, is the important basis for recovery stage. Our team did our utmost to restore the original appearance of stage in design, materials and craft by various tools, which include measured drawings in different times, old images collection, fine measuring by 3D laser scan, measurement of leftover pieces, logical inference.

  7. [The features of studies on cold pathogenic diseases in Yi zong jin jian (Golden mirror of orthodox medicine)].

    PubMed

    Huang, Hai

    2003-01-01

    As a voluminous work compiled and published by the Qing palace, Yi zong jin jian (Golden Mirror of Orthodox medicine) contains a "Revised Complete Book of Zhongjing" as its first volume which is very unique, systematic, and comprehensive. It re-categorizes the entries of the original Shang han lun (Treatiseon cold Tathogenic Diseases) based on its sections and chapters. and reasonably incorporates entries with similar contents. It also reasonably annotates those complex entries, boldly revises the wrong and missing entries, and applies the theories of "tripartite 3 outlines" as the basis for compiling the chapters and sections of Taiyang diseases, and as the tools for explaining the entries. Among them, some are compiled in verses for easy memory.

  8. Ke Wang, a Chinese television soap opera with a message.

    PubMed

    Wang, M; Singhal, A

    1992-01-01

    The Chinese soap opera, Ke Wang, was created by Li Xiaoming between August 1989 and June 1990 and produced at a cost of US$4650 per episode. The characters were drawn from everyday ordinary Chinese life: a traditional and open-minded and caring woman, a typical mother who works hard and loves her children, a highly educated upwardly mobile man who divorces his wife, a professor criticized during the Cultural Revolution, a doctor prejudiced against ordinary people, a kind honest man who marries the divorcee, a friend of the divorcee, a man who is optimistic in spite of bad experiences during the Cultural Revolution, and an excellent medical doctor who also resolves conflicts. The program was very popular, even among Communists, because of its value-based content, the real-life nature of the show, the change from highly restricted programming, the elaborate and supportive media coverage, and dialogue which closely matches audience preferences. The show has been aired by over 100 stations to date and has reached a total estimated audience of 550 million. The sale of television sets has increased since the show's appearance. The script reflects the conflicts between traditional and modern Chinese values. Pro-social values and behaviors are learned from the role models depicted; examples are given of immediate social impact. Ke Wang was a by-product of the Beijing Television Arts Center's interest in designing television programs that are relevant to the lives of ordinary people. The 60-minute scripts dealt with issues such as the status of women, social morality, family harmony, class conflict, responsible parenthood, maintenance of traditional culture, volunteerism, child development, and coping with physical disability. The Chinese government hailed Ke Wang as model television and awarded US$20,000 in prize money to the producers. The Chinese government is planning to produce other entertainment-education soap operas, which raises the problem of blatant, political

  9. Scalable replica-exchange framework for Wang-Landau sampling.

    PubMed

    Vogel, Thomas; Li, Ying Wai; Wüst, Thomas; Landau, David P

    2014-08-01

    We investigate a generic, parallel replica-exchange framework for Monte Carlo simulations based on the Wang-Landau method. To demonstrate its advantages and general applicability for massively parallel simulations of complex systems, we apply it to lattice spin models, the self-assembly process in amphiphilic solutions, and the adsorption of molecules on surfaces. While of general current interest, the latter phenomena are challenging to study computationally because of multiple structural transitions occurring over a broad temperature range. We show how the parallel framework facilitates simulations of such processes and, without any loss of accuracy or precision, gives a significant speedup and allows for the study of much larger systems and much wider temperature ranges than possible with single-walker methods.

  10. Improving Wang-Landau sampling with adaptive windows.

    PubMed

    Cunha-Netto, A G; Caparica, A A; Tsai, Shan-Ho; Dickman, Ronald; Landau, D P

    2008-11-01

    Wang-Landau sampling (WLS) of large systems requires dividing the energy range into "windows" and joining the results of simulations in each window. The resulting density of states (and associated thermodynamic functions) is shown to suffer from boundary effects in simulations of lattice polymers and the five-state Potts model. Here, we implement WLS using adaptive windows. Instead of defining fixed energy windows (or windows in the energy-magnetization plane for the Potts model), the boundary positions depend on the set of energy values on which the histogram is flat at a given stage of the simulation. Shifting the windows each time the modification factor f is reduced, we eliminate border effects that arise in simulations using fixed windows. Adaptive windows extend significantly the range of system sizes that may be studied reliably using WLS.

  11. Wang-Landau simulations of polymer adsorption on diluted surfaces

    NASA Astrophysics Data System (ADS)

    Martins, Paulo; Vogel, Thomas; Landau, David

    2012-02-01

    We consider a single linear lattice homopolymer in three dimensions that interacts with a diluted planar surface. A fraction p of the total number of the sites on the substrate is attractive, while the remaining 1-p remains neutral. Our focus is on the conformational transitions the polymer can experience under different environmental conditions, for instance, the surface dilution and the strength of the substrate attraction, compared to the intensity of the monomer-monomer interactions. To get insights on the phase diagram we have performed extensive Monte Carlo simulations, by using the Wang-Landau sampling, for different values of the surface attraction ɛ and the concentration of attractive sites p, specially near the surface percolation threshold pc.

  12. Scalable replica-exchange framework for Wang-Landau sampling

    NASA Astrophysics Data System (ADS)

    Vogel, Thomas; Li, Ying Wai; Wüst, Thomas; Landau, David P.

    2014-08-01

    We investigate a generic, parallel replica-exchange framework for Monte Carlo simulations based on the Wang-Landau method. To demonstrate its advantages and general applicability for massively parallel simulations of complex systems, we apply it to lattice spin models, the self-assembly process in amphiphilic solutions, and the adsorption of molecules on surfaces. While of general current interest, the latter phenomena are challenging to study computationally because of multiple structural transitions occurring over a broad temperature range. We show how the parallel framework facilitates simulations of such processes and, without any loss of accuracy or precision, gives a significant speedup and allows for the study of much larger systems and much wider temperature ranges than possible with single-walker methods.

  13. Improving Wang-Landau sampling with adaptive windows

    NASA Astrophysics Data System (ADS)

    Cunha-Netto, A. G.; Caparica, A. A.; Tsai, Shan-Ho; Dickman, Ronald; Landau, D. P.

    2008-11-01

    Wang-Landau sampling (WLS) of large systems requires dividing the energy range into “windows” and joining the results of simulations in each window. The resulting density of states (and associated thermodynamic functions) is shown to suffer from boundary effects in simulations of lattice polymers and the five-state Potts model. Here, we implement WLS using adaptive windows. Instead of defining fixed energy windows (or windows in the energy-magnetization plane for the Potts model), the boundary positions depend on the set of energy values on which the histogram is flat at a given stage of the simulation. Shifting the windows each time the modification factor f is reduced, we eliminate border effects that arise in simulations using fixed windows. Adaptive windows extend significantly the range of system sizes that may be studied reliably using WLS.

  14. Generic parallel Wang-Landau sampling for complex systems

    NASA Astrophysics Data System (ADS)

    Li, Ying Wai; Vogel, Thomas; Landau, David P.; Wüst, Thomas

    2013-03-01

    We introduce a parallel realization for Wang-Landau sampling in Monte Carlo simulations based on a replica-exchange framework. The key idea is to split the entire energy range of the system under consideration into several smaller, overlapping sub intervals. The survey of configurational phase space can then be distributed over multiple processors, with exchanges of random walkers taking place in the overlapping energy windows. To demonstrate the robustness and advantages of this parallel scheme for the simulations of complex systems, we have applied it to protein adsorption problems using the HP lattice protein model[1]. The method gives significant speed-up and achieves strong scaling on small computer architectures like multi-core processors, with a possible improvement in accuracy. We believe that it could be potentially beneficial for large-scale petaflop machines.

  15. Multiple Walkers in the Wang-Landau Algorithm

    SciTech Connect

    Brown, G

    2005-12-28

    The mean cost for converging an estimated density of states using the Wang-Landau algorithm is measured for the Ising and Heisenberg models. The cost increases in a power-law fashion with the number of spins, with an exponent near 3 for one-dimensional models, and closer to 2.4 for two-dimensional models. The effect of multiple, simultaneous walkers on the cost is also measured. For the one-dimensional Ising model the cost can increase with the number of walkers for large systems. For both the Ising and Heisenberg models in two-dimensions, no adverse impact on the cost is observed. Thus multiple walkers is a strategy that should scale well in a parallel computing environment for many models of magnetic materials.

  16. Wang-Landau Monte Carlo formalism applied to ferroelectrics

    NASA Astrophysics Data System (ADS)

    Bin-Omran, S.; Kornev, Igor A.; Bellaiche, L.

    2016-01-01

    The Wang-Landau Monte Carlo algorithm is implemented within an effective Hamiltonian approach and applied to BaTiO3 bulk. The density of states obtained by this approach allows a highly accurate and straightforward calculation of various thermodynamic properties, including phase transition temperatures, as well as polarization, dielectric susceptibility, specific heat, and electrocaloric coefficient at any temperature. This approach yields rather smooth data even near phase transitions and provides direct access to entropy and free energy, which allow us to compute properties that are typically unaccessible by atomistic simulations. Examples of such latter properties are the nature (i.e., first order versus second order) of the phase transitions for different supercell sizes and the thermodynamic limit of the Curie temperature and latent heat.

  17. [The textual research on the medical work of Wang tao].

    PubMed

    Song, Zhen-min

    2009-03-01

    Wang tao began to learn TCM as soon as he grew up, his teachers were proficient and famous doctors. He traveled and learned from them for several times and grasped their medical thoughts and technologies, therefore achieved profound medical accomplishments. Taking advantage of his medical background and occupation, he collected fifty and sixty kinds of medical data in prescription books of Jin and Tang dynasty from treasured books of Hong wen museum in Tianbao fifth to sixth years (746 -747) , when he served as Jishizhong of Ministry of Counseling and Functionary Management and administrated Hongwen museum. He then sorted them and compiled the famous work: Waitai Miyao (Arcane Essentials from the Imperial Library) in Tianbao 11th year (752).

  18. FORTRAN IV Compiler-Loader for the Wang 520/600 Calculator

    DTIC Science & Technology

    1976-03-01

    This paper describes a compiler system that will translate FORTRAN IV programs into programs that will run on the Wang 520/600 programmable ... calculator . The system includes an option to generate the Wang programs on punched cards that can be input into the 520 or 600 via a mark-sense card reader

  19. Exploring HP protein models using Wang-Landau sampling

    NASA Astrophysics Data System (ADS)

    Wuest, Thomas; Landau, David P.

    2008-03-01

    The hydrophobic-polar (HP) protein model has become a standard in assessing the efficiency of computational methods for protein structure prediction as well as for exploring the statistical physics of protein folding in general. Numerous methods have been proposed to address the challenges of finding minimal energy conformations within the rough energy landscape of this lattice heteropolymer model. However, only a few studies have been dedicated to the more revealing - but also more demanding - problem of estimating the density of states which allows access to thermodynamic properties of a system at any temperature. Here, we show that Wang-Landau sampling, in connection with a suitable move set (``pull moves''), provides a powerful route for the ground state search and the precise determination of the density of states for HP sequences (with up to 100 monomers) in both, two and three dimensions. Our procedure possesses an intrinsic simplicity and overcomes the inevitable limitations inherent in other more tailored approaches. The main advantage lies in its general applicability to a broad range of lattice protein models that go beyond the scope of the HP model.

  20. [Mr. Wang Le-ting: a master of acupuncture].

    PubMed

    Niu, Xue-Song; Wang, Fan

    2012-11-01

    Mr. WANG Le-ting attaches great importance to accurate differentiation of syndromes, strict selection of acupoints, technique and direction of needle insertion, clear reinforcing and reducing methods after the appearance of needling sensations, proper opportunities of manipulations as well as needle withdrawal techniques, and reasonable application of acupuncture and moxibustion respectively. The above mentioned principles are known as his "5 agreements". He emphasizes that the selection of acupoints should be "in accordance with both the meridians and the accurate location of the points", and "needling sensation is necessary for each point". He holds that the back-shu points of the five-zang organs and Geshu (BL 17) can be adopted for patient with deficiency of qi, blood, yin and yang. In the aspect of acupoint theory, he insists the accurate location of Xuanzhong (GB 39). He also adjusts the locations of Huatuo Jiaji (EX-B 2) points, and finds the location of the new Dubi (ST 35). For easier applications, he divides the functions of acupoints into different schools of qi, blood, cold, heat, deficiency, excess, wind and dampness. And 41 combinations of acupoints are also invented as innovation. He is always strict to his students, instructing and influencing them by his own words and deeds. He is always conscientious and meticulous, which benefit immensely his followers, and remains a lot of precious experiences for the later generations.

  1. The effect of Chinese herbal medicine Jian Ling Decoction for the treatment of essential hypertension: a systematic review

    PubMed Central

    Xiong, Xingjiang; Wang, Pengqian; Li, Xiaoke; Zhang, Yuqing

    2015-01-01

    Objectives Jian Ling Decoction (JLD) is often prescribed to improve hypertension-related symptoms in China. However, this treatment has not been systematically reviewed for its efficacy against essential hypertension (EH). This review aims to assess the current clinical evidence of JLD in the treatment of EH. Design Seven electronic databases, including the Cochrane Central Register of Controlled Trials, PubMed, EMBASE, the Chinese National Knowledge Infrastructure (CNKI), the Chinese Scientific Journal Database (VIP), the Chinese Biomedical Literature Database (CBM) and the Wanfang Database, were searched up to March 2014. Randomised control trials (RCTs) comparing JLD or combined with antihypertensive drugs versus antihypertensive drugs were included. We assessed the methodological quality, extracted the valid data and conducted the meta-analysis according to criteria from the Cochrane group. The primary outcome was categorical or continuous blood pressure (BP), and the secondary outcome was quality of life (QOL). Results Ten trials (655 patients) with unclear-to-high risk of bias were identified. Meta-analysis showed that JLD used alone showed no BP reduction effect; however, improvement on QOL was found in the JLD group compared to antihypertensive drugs. A significant reduction in systolic and diastolic BP was observed for JLD plus antihypertensive drugs when compared with antihypertensive drugs alone. No serious adverse effects were reported. Conclusions Owing to insufficient clinical data, it is difficult to draw a definite conclusion regarding the effectiveness and safety of JLD for EH, and better trials are needed. PMID:25652798

  2. Huang Qi Jian Zhong Pellet Attenuates TNBS-Induced Colitis in Rats via Mechanisms Involving Improvement of Energy Metabolism.

    PubMed

    Liu, Duan-Yong; Pan, Chun-Shui; Liu, Yu-Ying; Wei, Xiao-Hong; Zhou, Chang-Man; Sun, Kai; He, Ke; Li, Chong; Yan, Li; Fan, Jing-Yu; Wang, Chuan-She; Hibi, Toshifumi; Liu, Hong-Ning; Han, Jing-Yan

    2013-01-01

    Huang Qi Jian Zhong Pellet (HQJZ) is a famous Chinese medicine formula for treatment of various gastrointestinal tract diseases. This study investigated the role of HQJZ in 2,4,6-trinitrobenzene sulfonic acid- (TNBS-) induced colitis and its underlying mechanism. Colonic mucosal injury was induced by TNBS in the Sprague-Dawley rats. In the HQJZ treatment group, HQJZ was administered (2 g/kg) for 14 days starting from day 1 after TNBS infusion. Colonic mucosal injury occurred obviously 1 day after TNBS challenge and did not recover distinctively until day 15, including an increase in macro- and microscopic scores, a colonic weight index, a decrease in colonic length, a number of functional capillaries, and blood flow. Inverted intravital microscopy and ELISA showed colonic microcirculatory disturbances and inflammatory responses after TNBS stimulation, respectively. TNBS decreased occludin, RhoA, and ROCK-I, while increasing Rac-1, PAK-1, and phosphorylated myosin light chain. In addition, ATP content and ATP5D expression in colonic mucosa decreased after TNBS challenge. Impressively, treatment with HQJZ significantly attenuated all of the alterations evoked by TNBS, promoting the recovery of colonic injury. The present study demonstrated HQJZ as a multitargeting management for colonic mucosal injury, which set in motion mechanisms involving improvement of energy metabolism.

  3. A new paradigm for petascale Monte Carlo simulation: Replica exchange Wang-Landau sampling

    NASA Astrophysics Data System (ADS)

    Li, Ying Wai; Vogel, Thomas; Wüst, Thomas; Landau, David P.

    2014-05-01

    We introduce a generic, parallel Wang-Landau method that is naturally suited to implementation on massively parallel, petaflop supercomputers. The approach introduces a replica-exchange framework in which densities of states for overlapping sub-windows in energy space are determined iteratively by traditional Wang-Landau sampling. The advantages and general applicability of the method are demonstrated for several distinct systems that possess discrete or continuous degrees of freedom, including those with complex free energy landscapes and topological constraints.

  4. Generalizing Swendsen-Wang to sampling arbitrary posterior probabilities.

    PubMed

    Barbu, Adrian; Zhu, Song-Chun

    2005-08-01

    Many vision tasks can be formulated as graph partition problems that minimize energy functions. For such problems, the Gibbs sampler provides a general solution but is very slow, while other methods, such as Ncut and graph cuts are computationally effective but only work for specific energy forms and are not generally applicable. In this paper, we present a new inference algorithm that generalizes the Swendsen-Wang method to arbitrary probabilities defined on graph partitions. We begin by computing graph edge weights, based on local image features. Then, the algorithm iterates two steps. 1) Graph clustering: It forms connected components by cutting the edges probabilistically based on their weights. 2) Graph relabeling: It selects one connected component and flips probabilistically, the coloring of all vertices in the component simultaneously. Thus, it realizes the split, merge, and regrouping of a "chunk" of the graph, in contrast to Gibbs sampler that flips a single vertex. We prove that this algorithm simulates ergodic and reversible Markov chain jumps in the space of graph partitions and is applicable to arbitrary posterior probabilities or energy functions defined on graphs. We demonstrate the algorithm on two typical problems in computer vision--image segmentation and stereo vision. Experimentally, we show that it is 100-400 times faster in CPU time than the classical Gibbs sampler and 20-40 times faster then the DDMCMC segmentation algorithm. For stereo, we compare performance with graph cuts and belief propagation. We also show that our algorithm can automatically infer generative models and obtain satisfactory results (better than the graphic cuts or belief propagation) in the same amount of time.

  5. Hepatoprotective and antioxidant effects of dietary Glycyrrhiza polysaccharide against TCDD-induced hepatic injury and RT-PCR quantification of AHR2, ARNT2, CYP1A mRNA in Jian Carp (Cyprinus carpio var. Jian).

    PubMed

    Du, Jinliang; Cao, Liping; Jia, Rui; Yin, Guojun

    2017-01-01

    To evaluate the protective effects of Glycyrrhiza polysaccharide (GPS) against 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced hepatotoxicity in Jian carp, the fish were fed diets containing GPS at doses of 0.1, 0.5 and 1.0g/kg for 60days before an intraperitoneal injection of 0.6μg/kg TCDD at a volume of 0.05mL/10g body weight. At 72hr post-injection, blood and liver samples were taken for biochemical analysis and the fish liver samples were used for the preparation of pathological slices. The results showed that increases in alanine aminotransferase (GPT), aspartate aminotransferase (GOT), lactate dehydrogenase (LDH), and alkaline phosphatase (AKP) in serum induced by TCDD were significantly inhibited by pre-treatment with 1.0g/kg GPS. Following the 1.0g/kg GPS pre-treatment, total protein (TP), albumin (Alb), catalase (CAT), glutathione peroxidase (GPx), total antioxidant capacity (T-AOC) and superoxide dismutase (SOD) activities in liver tissue increased significantly, malondialdehyde (MDA) formation (P<0.05 or P<0.01) was significantly inhibited, and the expression of cytochrome P4501A (CYP1A), aryl hydrocarbon receptor 2 (AHR2) and aryl hydrocarbon receptor nuclear translocator 2 (ARNT2) mRNA (P<0.05) was significantly enhanced. Histological observations on fish liver were obtained by preparing paraffin tissue sections via HE staining, and the results showed that histological changes were obviously reduced by 0.5 and 1.0g/kg GPS. GPS significantly reduced liver tissue damage caused by TCDD. Overall, these results proved the hepatoprotective effect of GPS in protecting against fish liver injury induced by TCDD, and supported the use of GPS (1.0g/kg) as a hepatoprotective and antioxidant agent in fish.

  6. CORRIGENDUM: Prospects for a new boson W+/-1 in the minimal Higgsless model at the LHC Prospects for a new boson W+/-1 in the minimal Higgsless model at the LHC

    NASA Astrophysics Data System (ADS)

    Chen, Ming-Shui; Bian, Jian-Guo; Chen, Guo-Ming; He, Hong-Jian; Jiang, Chun-Hua; Li, Zu-Hao; Liang, Song; Meng, Xiang-Wei; Qi, Yong-Hui; Tang, Zhi-Cheng; Tao, Jun-Quan; Wang, Zheng; Wang, Jian; Wang, Jian; Wang, Xian-You; Wang, Jian-Xiong; Xiao, Hong; Yang, Min; Zang, Jing-Jing; Zhang, Bin; Zhang, Zhen; Zhang, Zhen-Xia

    2009-12-01

    The author list originally given in the above article (Ming-Shui Chen, Jian-Guo Bian, Guo-Ming Chen, Hong-Jian He, Chun-Hua Jiang, Zu-Hao Li, Song Liang, Xiang-Wei Meng, Yong-Hui Qi, Zhi-Cheng Tang, Jun-Quan Tao, Zheng Wang, Jian Wang, Jian Wang, Xian-You Wang, Jian-Xiong Wang, Hong Xiao, Min Yang, Jing-Jing Zang, Bin Zhang, Zhen Zhang and Zhen- Xia Zhang) is incorrect. The correct author list is: Ming-Shui Chen, Jian-Guo Bian, Guo-Ming Chen, Chun-Hua Jiang, Zu-Hao Li, Song Liang, Xiang-Wei Meng, Zhi-Cheng Tang, Jun-Quan Tao, Zheng Wang, Jian Wang, Jian Wang, Xian-You Wang, Jian-Xiong Wang, Hong Xiao, Min Yang, Jing-Jing Zang, Bin Zhang, Zhen Zhang and Zhen-Xia Zhang. Hong-Jian He and Yong-Hui Qi did not take part in the writing of this text and do not bear any responsibility for its contents. Also, reference [4] in the paper should be corrected to: [4] Hong-Jian He et al 2008 Phys. Rev. D 78 031701(R)

  7. Performance of replica-exchange Wang-Landau sampling for the study of spin systems

    NASA Astrophysics Data System (ADS)

    Li, Ying Wai; Eisenbach, Markus; Vogel, Thomas; Wüst, Thomas; Landau, David P.

    2014-03-01

    The recently proposed replica-exchange Wang-Landau sampling (REWL) is a novel, massively parallel Monte Carlo method which allows for the parallelization of Wang-Landau sampling based on a replica-exchange framework. The robustness of the scheme is demonstrated by its broad applicability on a variety of spin systems: from the simplest models with discrete or continuous energy domains, to complex systems captured by large-scale first principles density functional theory calculations. The accuracy of REWL is studied by comparing the thermodynamic properties with exact solutions and results obtained by the original, serial Wang-Landau sampling. The principles for the speed-up, the strong and weak scaling behavior of REWL are also investigated when different parameter settings are employed. We will show, with the aid of selected spin systems, that the method accelerates the simulations significantly with a possible improved accuracy. Phys. Rev. Lett. 110, 210603 (2013)

  8. Replica-exchange Wang Landau sampling: pushing the limits of Monte Carlo simulations in materials sciences

    SciTech Connect

    Perera, Meewanage Dilina N; Li, Ying Wai; Eisenbach, Markus; Vogel, Thomas; Landau, David P

    2015-01-01

    We describe the study of thermodynamics of materials using replica-exchange Wang Landau (REWL) sampling, a generic framework for massively parallel implementations of the Wang Landau Monte Carlo method. To evaluate the performance and scalability of the method, we investigate the magnetic phase transition in body-centered cubic (bcc) iron using the classical Heisenberg model parameterized with first principles calculations. We demonstrate that our framework leads to a significant speedup without compromising the accuracy and precision and facilitates the study of much larger systems than is possible with its serial counterpart.

  9. Aperiodic compression and reconstruction of real-world material systems based on Wang tiles

    NASA Astrophysics Data System (ADS)

    Doškář, Martin; Novák, Jan; Zeman, Jan

    2014-12-01

    The paper presents a concept to compress and synthesize complex material morphologies that is based on Wang tilings. Specifically, a microstructure is stored in a set of Wang tiles and its reconstruction is performed by means of a stochastic tiling algorithm. A substantial part of the study is devoted to the setup of optimal parameters of the automatic tile design by means of parametric studies with statistical descriptors at heart. The performance of the method is demonstrated on four two-dimensional two-phase target systems, monodisperse media with hard and soft disks, sandstone, and high porosity metallic foam.

  10. Aperiodic compression and reconstruction of real-world material systems based on Wang tiles.

    PubMed

    Doškář, Martin; Novák, Jan; Zeman, Jan

    2014-12-01

    The paper presents a concept to compress and synthesize complex material morphologies that is based on Wang tilings. Specifically, a microstructure is stored in a set of Wang tiles and its reconstruction is performed by means of a stochastic tiling algorithm. A substantial part of the study is devoted to the setup of optimal parameters of the automatic tile design by means of parametric studies with statistical descriptors at heart. The performance of the method is demonstrated on four two-dimensional two-phase target systems, monodisperse media with hard and soft disks, sandstone, and high porosity metallic foam.

  11. Commentary: A Closer Look at Task Analysis--Reactions to Wang, Schnipke, and Witt

    ERIC Educational Resources Information Center

    LaDuca, Tony

    2006-01-01

    In the Spring 2005 issue, Wang, Schnipke, and Witt provided an informative description of the task inventory approach that centered on four functions of job analysis. The discussion included persuasive arguments for making systematic connections between tasks and KSAs. But several other facets of the discussion were much less persuasive. This…

  12. Dynamically optimized Wang-Landau sampling with adaptive trial moves and modification factors.

    PubMed

    Koh, Yang Wei; Lee, Hwee Kuan; Okabe, Yutaka

    2013-11-01

    The density of states of continuous models is known to span many orders of magnitudes at different energies due to the small volume of phase space near the ground state. Consequently, the traditional Wang-Landau sampling which uses the same trial move for all energies faces difficulties sampling the low-entropic states. We developed an adaptive variant of the Wang-Landau algorithm that very effectively samples the density of states of continuous models across the entire energy range. By extending the acceptance ratio method of Bouzida, Kumar, and Swendsen such that the step size of the trial move and acceptance rate are adapted in an energy-dependent fashion, the random walker efficiently adapts its sampling according to the local phase space structure. The Wang-Landau modification factor is also made energy dependent in accordance with the step size, enhancing the accumulation of the density of states. Numerical simulations show that our proposed method performs much better than the traditional Wang-Landau sampling.

  13. Learning from Wang Yang-Ming: Exploring Oriental Contributions to Understanding Action Research

    ERIC Educational Resources Information Center

    Tickle, Les

    2005-01-01

    This article reports recent foraging for ideas in action research among the lives and intellects of Chinese society. It began and is reported as a personal journey, initially following the trail of the activist scholar Wang Yang-Ming. The method is a roam through some of the resources that have so far been discovered. The style is…

  14. Twisted gauge theories in three-dimensional Walker-Wang models

    NASA Astrophysics Data System (ADS)

    Wang, Zitao; Chen, Xie

    2017-03-01

    Three-dimensional gauge theories with a discrete gauge group can emerge from spin models as a gapped topological phase with fractional point excitations (gauge charge) and loop excitations (gauge flux). It is known that 3D gauge theories can be "twisted," in the sense that the gauge flux loops can have nontrivial braiding statistics among themselves and such twisted gauge theories are realized in models discovered by Dijkgraaf and Witten. A different framework to systematically construct three-dimensional topological phases was proposed by Walker and Wang and a series of examples have been studied. Can the Walker-Wang construction be used to realize the topological order in twisted gauge theories? This is not immediately clear because the Walker-Wang construction is based on a loop condensation picture while the Dijkgraaf-Witten theory is based on a membrane condensation picture. In this paper, we show that the answer to this question is Yes, by presenting an explicit construction of the Walker-Wang models which realize both the twisted and untwisted gauge theories with gauge group Z2×Z2 . We identify the topological order of the models by performing modular transformations on the ground-state wave functions and show that the modular matrices exactly match those for the Z2×Z2 gauge theories. By relating the Walker-Wang construction to the Dijkgraaf-Witten construction, our result opens up a way to study twisted gauge theories with fermonic charges, and correspondingly strongly interacting fermionic symmetry protected topological phases and their surface states, through exactly solvable models.

  15. Determination of gentiopicroside, mangiferin, palmatine, berberine, baicalin, wogonin and glycyrrhizin in the traditional Chinese medicinal preparation sann-joong-kuey-jian-tang by high-performance liquid chromatography.

    PubMed

    Lin, S J; Tseng, H H; Wen, K C; Suen, T T

    1996-04-12

    High-performance liquid chromatography was employed to determine the contents of several marker substances such as gentiopicroside, mangiferin, palmatine, berberine, baicalin, wogonin and glycyrrhizin in Sann-Joong-Kuey-Jian-Tang. The separation was performed on a Cosmosil 5C18-AR column by gradient elution with 0.03% (v/v) phosphoric acid-acetonitrile (0 min, 90:10; 10 min, 87:13; 17-27 min, 77:23; 40 min, 62:38; 50 min, 55:45) as the mobile phase at a flow-rate of 1.0 ml/min, with detection at 254 nm. n-Propylparaben was used as the internal standard and seven regression equations revealed linear relationships between the peak-area ratios (marker substances/internal standard) and concentrations. The repeatability and reproducibility (relative standard deviation) of the method were in the ranges 0.02-1.78% and 1.44-4.95%, respectively.

  16. Retraction Statement: 'MicroRNA-218 increases cellular sensitivity to Rapamycin via targeting Rictor in cervical cancer' by Li J, Wang J, Wang Y, Qiu H.

    PubMed

    2017-02-01

    The above article from APMIS, published online on 24 April 2015 in Wiley Online Library (wileyonlinelibrary.com) and in Volume 123, pp. 562-570, has been retracted by agreement between the authors, the journal Editors in Chief, Professors Bodil Norrild, Ben Vainer and Elisabeth Ralfkiaer, and John Wiley & Sons Ltd. The article has been retracted due to errors in the reported results. In this study, the authors used HeLa and SiHa cell lines to investigate the biological roles of miR-218. However, subsequently it emerged that the two cell lines were contaminated in the laboratory by other unknown cell lines. When repeating the experiments, it was found that the functions of miR-218 were not as significant as had been previously reported, especially its effects on rapamycin sensitivity. Reference Li J, Li X, Wang J, Wang Y, Qiu H. MicroRNA-218 increases cellular sensitivity to Rapamycin via targeting Rictor in cervical cancer. APMIS 2015; 123:562-570. doi: 10.1111/apm.12387.

  17. Four systems involved with congenital abnormalities: a new type of syndromic hearing loss - ADOC Wang's syndrome?

    PubMed

    Wang, Qiuju; Zhao, Fei-Fan; Shi, Yong-Bing

    2011-10-01

    Syndromic hearing impairment encompasses hundreds of phenotypes. We identified a young female patient affected by the unique combination of dysplasia of the auricular system, patent ductus arteriosus (PDA), choroideremia, and enamel hypoplasia. The patient was treated with PDA ligature and left exploratory tympanotomy. Impairment in all four systems suggests a correlation with the neural crest. It is presumed that all of the features result from the same origin, probably through autosomal recessive inheritance or a novel mutation during the embryonic period. When audio-dento-oculo-cardio systems are involved, we suggest that this new syndrome can be named 'ADOC Wang's syndrome', summarizing the disorders of the four systems and indicative of the founding person (Dr Wang, the first and corresponding author of the paper).

  18. Application of the Wang-Landau Monte-Carlo Formalism applied to Ferroelectrics materials

    NASA Astrophysics Data System (ADS)

    Bin Omran, Saad; Kornev, Igor; Bellaiche, Laurent

    The conventional description of phase transitions in ferroelectrics is based on canonical thermodynamic functions and always assumes the thermodynamic limit of an infinite system. However, ferroelectrics at nanoscale recently became of high interest due to their potential applications in minuaturized devices. It is this timely and more appropriate to use the microcanonical ensemble when mimicking ferroelectric systems. Interestingly, a Monte Carlo method based on the density of states (or microcanonical ensemble partition function) proposed by Wang and Landau has the potential to over-come these difficulties. Here, the Wang-Landau Monte Carlo algorithm is implemented within an effective Hamiltonian approach and used to conduct a detailed study of physical properties of BaTiO3 bulk. In this presentation, we will show how this approach allows a highly-accurate and straightforward calculation of various thermodynamic properties, including phase transition temperatures, as well as polarization, dielectric susceptibility, specific heat and electrocaloric coefficient at any temperature.

  19. Wang-Landau Reaction Ensemble Method: Simulation of Weak Polyelectrolytes and General Acid-Base Reactions.

    PubMed

    Landsgesell, Jonas; Holm, Christian; Smiatek, Jens

    2017-02-14

    We present a novel method for the study of weak polyelectrolytes and general acid-base reactions in molecular dynamics and Monte Carlo simulations. The approach combines the advantages of the reaction ensemble and the Wang-Landau sampling method. Deprotonation and protonation reactions are simulated explicitly with the help of the reaction ensemble method, while the accurate sampling of the corresponding phase space is achieved by the Wang-Landau approach. The combination of both techniques provides a sufficient statistical accuracy such that meaningful estimates for the density of states and the partition sum can be obtained. With regard to these estimates, several thermodynamic observables like the heat capacity or reaction free energies can be calculated. We demonstrate that the computation times for the calculation of titration curves with a high statistical accuracy can be significantly decreased when compared to the original reaction ensemble method. The applicability of our approach is validated by the study of weak polyelectrolytes and their thermodynamic properties.

  20. Wang-Landau sampling in face-centered-cubic hydrophobic-hydrophilic lattice model proteins.

    PubMed

    Liu, Jingfa; Song, Beibei; Yao, Yonglei; Xue, Yu; Liu, Wenjie; Liu, Zhaoxia

    2014-10-01

    Finding the global minimum-energy structure is one of the main problems of protein structure prediction. The face-centered-cubic (fcc) hydrophobic-hydrophilic (HP) lattice model can reach high approximation ratios of real protein structures, so the fcc lattice model is a good choice to predict the protein structures. The lacking of an effective global optimization method is the key obstacle in solving this problem. The Wang-Landau sampling method is especially useful for complex systems with a rough energy landscape and has been successfully applied to solving many optimization problems. We apply the improved Wang-Landau (IWL) sampling method, which incorporates the generation of an initial conformation based on the greedy strategy and the neighborhood strategy based on pull moves into the Wang-Landau sampling method to predict the protein structures on the fcc HP lattice model. Unlike conventional Monte Carlo simulations that generate a probability distribution at a given temperature, the Wang-Landau sampling method can estimate the density of states accurately via a random walk, which produces a flat histogram in energy space. We test 12 general benchmark instances on both two-dimensional and three-dimensional (3D) fcc HP lattice models. The lowest energies by the IWL sampling method are as good as or better than those of other methods in the literature for all instances. We then test five sets of larger-scale instances, denoted by the S, R, F90, F180, and CASP target instances on the 3D fcc HP lattice model. The numerical results show that our algorithm performs better than the other five methods in the literature on both the lowest energies and the average lowest energies in all runs. The IWL sampling method turns out to be a powerful tool to study the structure prediction of the fcc HP lattice model proteins.

  1. Exploring new frontiers in statistical physics with a new, parallel Wang-Landau framework

    NASA Astrophysics Data System (ADS)

    Vogel, Thomas; Li, Ying Wai; Wüst, Thomas; Landau, David P.

    2014-03-01

    Combining traditional Wang-Landau sampling for multiple replica systems with an exchange of densities of states between replicas, we describe a general framework for simulations on massively parallel Petaflop supercomputers. The advantages and general applicability of the method for simulations of complex systems are demonstrated for the classical 2D Potts spin model featuring a strong first-order transition and the self-assembly of lipid bilayers in amphiphilic solutions in a continuous model.

  2. Two alternate proofs of Wang's lune formula for sparse distributed memory and an integral approximation

    NASA Technical Reports Server (NTRS)

    Jaeckel, Louis A.

    1988-01-01

    In Kanerva's Sparse Distributed Memory, writing to and reading from the memory are done in relation to spheres in an n-dimensional binary vector space. Thus it is important to know how many points are in the intersection of two spheres in this space. Two proofs are given of Wang's formula for spheres of unequal radii, and an integral approximation for the intersection in this case.

  3. Exploring Replica-Exchange Wang-Landau sampling in higher-dimensional parameter space

    NASA Astrophysics Data System (ADS)

    Valentim, Alexandra; Rocha, Julio C. S.; Tsai, Shan-Ho; Li, Ying Wai; Eisenbach, Markus; Fiore, Carlos E.; Landau, David P.

    2015-09-01

    We considered a higher-dimensional extension for the replica-exchange Wang- Landau algorithm to perform a random walk in the energy and magnetization space of the two-dimensional Ising model. This hybrid scheme combines the advantages of Wang-Landau and Replica-Exchange algorithms, and the one-dimensional version of this approach has been shown to be very efficient and to scale well, up to several thousands of computing cores. This approach allows us to split the parameter space of the system to be simulated into several pieces and still perform a random walk over the entire parameter range, ensuring the ergodicity of the simulation. Previous work, in which a similar scheme of parallel simulation was implemented without using replica exchange and with a different way to combine the result from the pieces, led to discontinuities in the final density of states over the entire range of parameters. From our simulations, it appears that the replica-exchange Wang-Landau algorithm is able to overcome this difficulty, allowing exploration of higher parameter phase space by keeping track of the joint density of states.

  4. Highly parallel computational study of amphiphilic molecules using the Wang--Landau method

    NASA Astrophysics Data System (ADS)

    Vogel, Thomas; Landau, David

    2012-02-01

    The self-assembly process in amphiphilic solutions is a phenomenon of broad interest. Molecular dynamics simulations generally used to study micelle formation or lipid layer assembly in an explicit solvent are limited in time scale. Vast studies of structure formation processes via standard Markov-chain based Monte Carlo simulations are challenging, but the Wang--Landau method [1] provides a way to efficiently study such systems in a generalized thermodynamic ensemble. This makes it possible, for example, to get results over a broad temperature range from a single simulation. In an attempt to develop highly parallel applications using this method, we study the thermodynamic behavior of a generic coarse-grained model for amphiphilic molecules [2] as well as of a new coarse-grained lipid model specifically designed for dimyristoyl phosphatidylcholine (DMPC) [3]. Here, we focus on the design and the performance of our parallel Wang--Landau simulation on multi-CPU and GPU systems.[4pt] [1] F. Wang and D.P. Landau, Phys. Rev. Lett. 86, 2050 (2001)[0pt] [2] S. Fujiwara et al., J. Chem. Phys. 130, 144901 (2009)[0pt] [3] W. Shinoda et al., J. Phys. Chem. B 114, 6836 (2010)

  5. Dynamical traps in Wang-Landau sampling of continuous systems: Mechanism and solution

    NASA Astrophysics Data System (ADS)

    Koh, Yang Wei; Sim, Adelene Y. L.; Lee, Hwee Kuan

    2015-08-01

    We study the mechanism behind dynamical trappings experienced during Wang-Landau sampling of continuous systems reported by several authors. Trapping is caused by the random walker coming close to a local energy extremum, although the mechanism is different from that of the critical slowing-down encountered in conventional molecular dynamics or Monte Carlo simulations. When trapped, the random walker misses the entire or even several stages of Wang-Landau modification factor reduction, leading to inadequate sampling of the configuration space and a rough density of states, even though the modification factor has been reduced to very small values. Trapping is dependent on specific systems, the choice of energy bins, and the Monte Carlo step size, making it highly unpredictable. A general, simple, and effective solution is proposed where the configurations of multiple parallel Wang-Landau trajectories are interswapped to prevent trapping. We also explain why swapping frees the random walker from such traps. The efficacy of the proposed algorithm is demonstrated.

  6. Dynamical traps in Wang-Landau sampling of continuous systems: Mechanism and solution.

    PubMed

    Koh, Yang Wei; Sim, Adelene Y L; Lee, Hwee Kuan

    2015-08-01

    We study the mechanism behind dynamical trappings experienced during Wang-Landau sampling of continuous systems reported by several authors. Trapping is caused by the random walker coming close to a local energy extremum, although the mechanism is different from that of the critical slowing-down encountered in conventional molecular dynamics or Monte Carlo simulations. When trapped, the random walker misses the entire or even several stages of Wang-Landau modification factor reduction, leading to inadequate sampling of the configuration space and a rough density of states, even though the modification factor has been reduced to very small values. Trapping is dependent on specific systems, the choice of energy bins, and the Monte Carlo step size, making it highly unpredictable. A general, simple, and effective solution is proposed where the configurations of multiple parallel Wang-Landau trajectories are interswapped to prevent trapping. We also explain why swapping frees the random walker from such traps. The efficacy of the proposed algorithm is demonstrated.

  7. Exploring Replica-Exchange Wang-Landau sampling in higher-dimensional parameter space

    SciTech Connect

    Valentim, Alexandra; Rocha, Julio C. S.; Tsai, Shan-Ho; Li, Ying Wai; Eisenbach, Markus; Fiore, Carlos E; Landau, David P

    2015-01-01

    We considered a higher-dimensional extension for the replica-exchange Wang-Landau algorithm to perform a random walk in the energy and magnetization space of the two-dimensional Ising model. This hybrid scheme combines the advantages of Wang-Landau and Replica-Exchange algorithms, and the one-dimensional version of this approach has been shown to be very efficient and to scale well, up to several thousands of computing cores. This approach allows us to split the parameter space of the system to be simulated into several pieces and still perform a random walk over the entire parameter range, ensuring the ergodicity of the simulation. Previous work, in which a similar scheme of parallel simulation was implemented without using replica exchange and with a different way to combine the result from the pieces, led to discontinuities in the final density of states over the entire range of parameters. From our simulations, it appears that the replica-exchange Wang-Landau algorithm is able to overcome this diculty, allowing exploration of higher parameter phase space by keeping track of the joint density of states.

  8. Sann-Joong-Kuey-Jian-Tang increases the protein expression of microtubule-associated protein II light chain 3 in human colon cancer colo 205 cells.

    PubMed

    Cheng, Chun-Yuan; Lin, Yi-Hsiang; Su, Chin-Cheng

    2009-01-01

    Sann-Joong-Kuey-Jian-Tang (SJKJT), a traditional Chinese medicine, has been prescribed as complementary medication for colon cancer in Taiwan. However, its molecular mechanisms are not yet understood. In the present study, we investigated the effects of SJKJT on human colon cancer colo 205 cells in vitro. The cytotoxicity of SJKJT in colo 205 cells was evaluated using the MTT assay, and the protein expression of microtubule-associated protein II light chain 3 (MAP-LC3-II) was measured using Western blot analysis. The results showed that SJKJT inhibited the survival rates of colo 205 cells in a time- and dose-dependent manner, with an IC50 concentration at 24 h of 590.34 µg/ml. In addition, SJKJT up-regulated the protein expression of MAP-LC3-II in colo 205 cells. These findings indicate that one of the molecular mechanisms by which SJKJT inhibits the proliferation of colo 205 cells in?vitro may be through the induction of the autophagic pathway. SJKJT may therefore have therapeutic potential for the treatment of human colon cancer.

  9. Chinese Medicine Formula “Jian-Pi-Zhi-Dong Decoction” Attenuates Tourette Syndrome via Downregulating the Expression of Dopamine Transporter in Mice

    PubMed Central

    Wang, Dao-han; Li, Wei; Liu, Xiao-fang; Zhang, Jin-ming; Wang, Su-mei

    2013-01-01

    Jian-Pi-Zhi-Dong Decoction (JPZDD) is dedicated to the treatment for Tourette syndrome (TS) with the guidance of the theories of Traditional Chinese Medicine (TCM). This study aims to investigate the expression of dopamine transporter (DAT) in the striatum and stereotyped behavior of TS mice model by intervention of JPZDD. Mice were induced by 3,3′-iminodipropionitrile (IDPN, 350 mg kg−1 day−1, i.p.) for 7 days and divided into 4 groups (n = 20, each): control and IDPN groups were gavaged with saline and the remaining 2 groups with Tiapride (Tia, 50 mg kg−1 day−1) and JPZDD (20 g kg−1 day−1), respectively. The results showed that the scores of stereotyped behavior in IDPN+JPZDD group were significantly reduced. A noticeably increased 11C-β-CFT binding at bilateral striatum was observed after administration of JPZDD versus that of IDPN or Tia. Immunohistochemistry and in situ hybridization studies manifested higher levels of DAT protein and mRNA in IDPN+JPZDD group. These findings not only demonstrated that JPZDD could effectively inhibit the abnormal behaviors of TS mice model, but also increase the level of DAT in striatum. Therefore, JPZDD could be one of potential treatments of patients with TS. PMID:23431337

  10. Effects of the traditional Chinese medicine Yi Shen Jian Gu granules on aromatase inhibitor-associated musculoskeletal symptoms: a study protocol for a multicenter, randomized, controlled clinical trial

    PubMed Central

    2014-01-01

    Background Aromatase inhibitors (AIs) are widely used as an adjuvant endocrine treatment in postmenopausal women with early-stage breast cancer. One of the main adverse effects of AIs is musculoskeletal symptoms, which leads to a lower quality of life and poor adherence to AI treatment. To date, no effective management of aromatase inhibitor-associated musculoskeletal symptoms (AIMSS) has been developed. Methods/design To determine whether the traditional Chinese medicine Yi Shen Jian Gu granules could effectively manage AIMSS we will conduct a multicenter, randomized, double-blind, placebo-controlled clinical trial. Patients experiencing musculoskeletal symptoms after taking AIs will be enrolled and treated with traditional Chinese medicine or placebo for 12 weeks. The primary outcome measures include Brief Pain Inventory-Short Form, Western Ontario and McMaster Universities Osteoarthritis Index, and Modified Score for the Assessment and Quantification of Chronic Rheumatoid Affections of the Hands, which will be obtained at baseline and at 4, 8, 12 and 24 weeks. Discussion The results of this study will provide a new strategy to help relieve AIMSS. Trial registration ISCTN: ISRCTN06129599 (assigned 14 August 2013). PMID:24885324

  11. Soil Organic Carbon Pool and Its Chemical Composition in Phyllostachy pubescens Forests at Two Altitudes in Jian-ou City, China

    PubMed Central

    Ji, Haibao; Zhuang, Shunyao; Zhu, Zhaoliang; Zhong, Zheke

    2015-01-01

    Phyllostachys pubescens forests play an important role in soil organic carbon (SOC) sequestration in terrestrial ecosystems. However, the estimation and mechanism of SOC sequestration by P. pubescens forests remain unclear. In this study, the effect of P. pubescens forest distribution with elevation was investigated at two altitude sites in Jian-ou City, Southeast China. SOC storage was estimated and its chemical composition was obtained via 13C-nuclear magnetic resonance (NMR), chemical classification, and spectral analysis. Results showed that the SOC contents and stocks were significantly higher at the high-altitude site than at the low-altitude site in the entire soil profile (0–60 cm). The C contents of the three combined humus forms exhibited similar responses to the elevation change, and all of these forms were higher at the high-altitude site than at the low-altitude site regardless of soil layer. However, the proportions of the three combined humus C showed no significant differences between the two altitudes. The results of 13C-NMR showed that the SOC chemical composition did not significantly vary with elevation as well. This finding was consistent with the E465/E665 of the loosely combined humus. Overall, the results suggested that altitude should be considered during regional SOC estimation and that altitude affected the quantity rather than the quality of the SOC under the same P. pubescens vegetation. PMID:26716688

  12. Soil Organic Carbon Pool and Its Chemical Composition in Phyllostachy pubescens Forests at Two Altitudes in Jian-ou City, China.

    PubMed

    Ji, Haibao; Zhuang, Shunyao; Zhu, Zhaoliang; Zhong, Zheke

    2015-01-01

    Phyllostachys pubescens forests play an important role in soil organic carbon (SOC) sequestration in terrestrial ecosystems. However, the estimation and mechanism of SOC sequestration by P. pubescens forests remain unclear. In this study, the effect of P. pubescens forest distribution with elevation was investigated at two altitude sites in Jian-ou City, Southeast China. SOC storage was estimated and its chemical composition was obtained via 13C-nuclear magnetic resonance (NMR), chemical classification, and spectral analysis. Results showed that the SOC contents and stocks were significantly higher at the high-altitude site than at the low-altitude site in the entire soil profile (0-60 cm). The C contents of the three combined humus forms exhibited similar responses to the elevation change, and all of these forms were higher at the high-altitude site than at the low-altitude site regardless of soil layer. However, the proportions of the three combined humus C showed no significant differences between the two altitudes. The results of 13C-NMR showed that the SOC chemical composition did not significantly vary with elevation as well. This finding was consistent with the E465/E665 of the loosely combined humus. Overall, the results suggested that altitude should be considered during regional SOC estimation and that altitude affected the quantity rather than the quality of the SOC under the same P. pubescens vegetation.

  13. Wang-Landau Algorithm for Continuous Models and Joint Density of States

    SciTech Connect

    Zhou, Chenggang; Schulthess, Thomas C; Torbrugge, S.; Landau, D. P.

    2006-01-01

    We present a modified Wang-Landau algorithm for models with continuous degrees of freedom. We demonstrate this algorithm with the calculation of the joint density of states of ferromagnet Heisenberg models and a model polymer chain. The joint density of states contains more information than the density of states of a single variable-energy, but is also much more time consuming to calculate. We present strategies to significantly speed up this calculation for large systems over a large range of energy and order parameter.

  14. Security analysis of boolean algebra based on Zhang-Wang digital signature scheme

    NASA Astrophysics Data System (ADS)

    Zheng, Jinbin

    2014-10-01

    In 2005, Zhang and Wang proposed an improvement signature scheme without using one-way hash function and message redundancy. In this paper, we show that this scheme exits potential safety concerns through the analysis of boolean algebra, such as bitwise exclusive-or, and point out that mapping is not one to one between assembly instructions and machine code actually by means of the analysis of the result of the assembly program segment, and which possibly causes safety problems unknown to the software.

  15. Wang-Landau algorithm for continuous models and joint density of states.

    PubMed

    Zhou, Chenggang; Schulthess, T C; Torbrügge, Stefan; Landau, D P

    2006-03-31

    We present a modified Wang-Landau algorithm for models with continuous degrees of freedom. We demonstrate this algorithm with the calculation of the joint density of states of ferromagnet Heisenberg models and a model polymer chain. The joint density of states contains more information than the density of states of a single variable-energy, but is also much more time consuming to calculate. We present strategies to significantly speed up this calculation for large systems over a large range of energy and order parameter.

  16. Unraveling the Beautiful Complexity of Simple Lattice Model Polymers and Proteins Using Wang-Landau Sampling

    NASA Astrophysics Data System (ADS)

    Wüst, T.; Li, Y. W.; Landau, D. P.

    2011-08-01

    We describe a class of "bare bones" models of homopolymers which undergo coil-globule collapse and proteins which fold into their native states in free space or into denatured states when captured by an attractive substrate as the temperature is lowered. We then show how, with the use of a properly chosen trial move set, Wang-Landau Monte Carlo sampling can be used to study the rough free energy landscape and ground (native) states of these intriguingly simple systems and thus elucidate their thermodynamic complexity.

  17. A Wang-Landau study of the phase transitions in a flexible homopolymer

    NASA Astrophysics Data System (ADS)

    Seaton, D. T.; Wüst, T.; Landau, D. P.

    2009-04-01

    Using Wang-Landau sampling we study the characteristic behavior of a flexible homopolymer (off-lattice) for chain lengths up to N=300. The Hamiltonian consists of a Lennard-Jones potential between all monomers, and an additional FENE potential between bonded monomers. From the resultant density of states, we calculate thermodynamic properties for a wide range of temperatures, including low temperatures that are inaccessible to traditional Monte Carlo algorithms. Peaks in the specific heat and radius of gyration indicate the coil-globule and solid-liquid transitions. With a careful implementation of the algorithm, we find no evidence of a liquid-liquid transition.

  18. Two-Dimensional Wang-Landau Sampling of AN Asymmetric Ising Model

    NASA Astrophysics Data System (ADS)

    Tsai, Shan-Ho; Wang, Fugao; Landau, D. P.

    We study the critical endpoint behavior of an asymmetric Ising model with two- and three-body interactions on a triangular lattice, in the presence of an external field. We use a two-dimensional Wang-Landau sampling method to determine the density of states for this model. An accurate density of states allowed us to map out the phase diagram accurately and observe a clear divergence of the curvature of the spectator phase boundary and of the derivative of the magnetization coexistence diameter near the critical endpoint, in agreement with previous theoretical predictions.

  19. Conformational transitions of a confined lattice protein: A Wang-Landau study

    NASA Astrophysics Data System (ADS)

    Pattanasiri, Busara; Li, Ying Wai; Landau, David P.; Wüst, Thomas; Triampo, Wannapong

    2012-12-01

    We use Wang-Landau sampling with suitable Monte Carlo trial moves to study a hydrophobic-polar (HP) lattice protein confined between two parallel, attractive walls. The density of states is determined iteratively by a random walk in energy space. Thermodynamic and structural properties, such as specific heat, number of surface contacts and number of H-H monomer pairs, are then calculated. When the surface attraction is comparable to the internal attraction among the hydrophobic monomers in the chain, two conformational “transitions”, adsorption at higher temperature and collapse at lower temperature, have been analyzed based on these properties. This transition behavior depends on the variation of surface separation.

  20. Wang-Landau Algorithm for Continuous Models and Joint Density of States

    NASA Astrophysics Data System (ADS)

    Zhou, Chenggang; Schulthess, T. C.; Torbrügge, Stefan; Landau, D. P.

    2006-03-01

    We present a modified Wang-Landau algorithm for models with continuous degrees of freedom. We demonstrate this algorithm with the calculation of the joint density of states of ferromagnet Heisenberg models and a model polymer chain. The joint density of states contains more information than the density of states of a single variable-energy, but is also much more time consuming to calculate. We present strategies to significantly speed up this calculation for large systems over a large range of energy and order parameter.

  1. Conodont index fossil Hindeodus changxingensis Wang fingers greatest mass extinction event

    USGS Publications Warehouse

    Metcalfe, I.; Nicoll, R.S.; Wardlaw, B.R.

    2007-01-01

    The marine conodont fossil species, Hindeodus changxingensis Wang, that has a distinctive morphology, is restricted to a very narrow stratigraphic interval essentially from the Permian-Triassic extinction event through the internationally recognized boundary and into the very earliest Triassic. The species is geographically widespread in the Tethyan Region, from Italy to South China, and serves as a characteristic index fossil to reliably identify this short but critical interval that encompasses the greatest mass extinction of life on earth and the boundary between the Paleozoic and Mesozoic Eras. ?? 2007 Nanjing Institute of Geology and Palaeontology, CAS.

  2. Protein folding of the H0P model: A parallel Wang-Landau study

    SciTech Connect

    Shi, Guangjie; Wuest, Thomas; Li, Ying Wai; Landau, David P

    2015-01-01

    We propose a simple modication to the hydrophobic-polar (HP) protein model, by introducing a new type of monomer, "0", with intermediate hydrophobicity of some amino acids between H and P. With the replica-exchange Wang-Landau sampling method, we investigate some widely studied HP sequences as well as their H0P counterparts and observe that the H0P sequences exhibit dramatically reduced ground state degeneracy and more signicant transition signals at low temperature for some thermodynamic properties, such as the specific heat.

  3. Difference of energy density of states in the Wang-Landau algorithm.

    PubMed

    Komura, Yukihiro; Okabe, Yutaka

    2012-01-01

    Paying attention to the difference of density of states, Δln g(E)≡ln g(E+ΔE)-lng(E), we study the convergence of the Wang-Landau method. We show that this quantity is a good estimator to discuss the errors of convergence and refer to the 1/t algorithm. We also examine the behavior of the first-order transition with this difference of density of states in connection with Maxwell's equal area rule. A general procedure to judge the order of transition is given.

  4. Replica-exchange Wang-Landau simulations of the H0P model of protein folding

    NASA Astrophysics Data System (ADS)

    Shi, Guangjie; Landau, David P.; Wüst, Thomas; Li, Ying Wai Li

    2015-03-01

    The hydrophobic-polar (HP) model has served as a coarse-grained lattice protein folding model attracting scientists from various disciplines. However, simplification into H and P monomers may yield high ground state degeneracies which stands in contrast to the generally unique native states of natural proteins. We propose a simple modification, by introducing a new type of ``neutral'' monomer, 0, i.e. neither hydrophobic nor polar, rendering the model more realistic without increasing the difficulties of sampling significantly. With the newly developed parallel Wang-Landau (replica exchange Wang-Landau) scheme and an innovative method of estimating the ground state degeneracies, we investigated some widely studied HP proteins and their H0P counterparts. Dramatic differences in ground state and thermodynamic properties have been observed, e.g. the estimation of ground state degeneracy for the 46mer is 460,000 for the HP version and only 20 for the H0P mapping. Similarly, the specific heat and structural properties: radius of gyration and etc. show more pronounced signals associated with folding. Supported by NSF.

  5. Phase equilibria of molecular fluids via hybrid Monte Carlo Wang-Landau simulations: applications to benzene and n-alkanes.

    PubMed

    Desgranges, Caroline; Delhommelle, Jerome

    2009-06-28

    In recent years, powerful and accurate methods, based on a Wang-Landau sampling, have been developed to determine phase equilibria. However, while these methods have been extensively applied to study the phase behavior of model fluids, they have yet to be applied to molecular systems. In this work, we show how, by combining hybrid Monte Carlo simulations in the isothermal-isobaric ensemble with the Wang-Landau sampling method, we determine the vapor-liquid equilibria of various molecular fluids. More specifically, we present results obtained on rigid molecules, such as benzene, as well as on flexible chains of n-alkanes. The reliability of the method introduced in this work is assessed by demonstrating that our results are in excellent agreement with the results obtained in previous work on simple fluids, using either transition matrix or conventional Monte Carlo simulations with a Wang-Landau sampling, and on molecular fluids, using histogram reweighting or Gibbs ensemble Monte Carlo simulations.

  6. Sann-Joong-Kuey-Jian-Tang up-regulates the protein expression of Fas and TNF-α in colo 205 cells in vivo and in vitro.

    PubMed

    Cheng, Chun-Yuan; Lin, Yi-Hsiang; Su, Chin-Cheng

    2010-01-01

    Sann-Joong-Kuey-Jian-Tang (SJKJT), a traditional Chinese medicine prescription, has been used to treat lymph node diseases and tumors. However, the molecular mechanisms of SJKJT in human colon cancer in vivo and in vitro have not been clearly elucidated. In the present study, we investigated the molecular mechanisms of SJKJT in human colon cancer colo 205 cells in vitro and in vivo. In the in vitro study, colo 205 cells were treated with various concentrations (0.5, 1 and 2 mg/ml) of SJKJT. The protein expression of TNF-α, Caspase-8 and Caspase-3 in colo 205 cells was measured by Western blotting. The results demonstrate that SJKJT up-regulated Fas, TNF-α, Caspase-8 and Caspase-3 protein expression. In the in vivo study, human colon cancer colo 205 cells (3x106/0.2 ml) were injected subcutaneously into the flank area of nude SCID mice (n=32) randomly divided into four groups. SJKJT was dissolved in saline and then administered orally to the mice at concentrations of 0.01, 0.1 and 0.3 g/kg/day for 30 days. The control group was treated with an equal volume of saline. SCID mice were sacrified by CO2 inhalation and the xenograft tumors were dissected. Subsequently, the protein expression of Fas, TNF-α, Caspase-8 and Caspase-3 in the tumors was measured by Western blotting. The results demonstrate that SJKJT up-regulated Fas, TNF-α, Caspase-8 and Caspase-3 protein expression, both in vitro and in vivo. These observations suggest that SJKJT has therapeutic potential in colon cancer.

  7. Urine metabolic profile changes of CCl4-liver fibrosis in rats and intervention effects of Yi Guan Jian Decoction using metabonomic approach

    PubMed Central

    2013-01-01

    Background Yi Guan Jian Decoction (YGJD), a famous Chinese prescription, has long been employed clinically to treat liver fibrosis. However, as of date, there is no report on the effects of YGJD from a metabonomic approach. In this study, a urine metabonomic method based on gas chromatography coupled with mass spectrometry (GC/MS) was employed to study the protective efficacy and metabolic profile changes caused by YGJD in carbon tetrachloride (CCl4)-induced liver fibrosis. Methods Urine samples from Wistar rats of three randomly divided groups (control, model, and YGJD treated) were collected at various time-points, and the metabolic profile changes were analyzed by GC/MS with principal component analysis (PCA) and partial least squares-discriminate analysis (PLS-DA). Furthermore, histopathology and biochemical examination were also carried out to ensure the success of CCl4-induced liver fibrosis model. Results Urine metabolic profile studies suggested distinct clustering of the three groups, and YGJD group was much closer to the control group by showing a tendency of recovering towards the control group. Fourteen significantly changed metabolites were found, and YGJD treatment could reverse the levels of these metabolites to normal levels or close to normal levels. Conclusions The current study indicates that the YGJD has significant anti-fibrotic effects on CCl4-induced liver fibrosis in rats, which might be by regulating the dysfunction of energy metabolism, amino acid metabolism, tryptophan metabolism, cytochrome P450 metabolism, and gut microflora metabolism. The metabonomic approach can be recommended to study the pharmacological effect and mechanism of complex Chinese medicines. PMID:23725349

  8. Effect of Yi Guan Jian decoction on differentiation of bone marrow mesenchymalstem cells into hepatocyte-like cells in dimethylnitrosamine-induced liver cirrhosis in mice.

    PubMed

    Xiang, Yan; Pang, Bing-Yao; Zhang, Yuan; Xie, Qiao-Ling; Zhu, Ying; Leng, Ai-Jing; Lu, Long-Qing; Chen, Hai-Long

    2017-02-01

    Yi Guan Jian decoction (YGD) may induce the differentiation of bone marrow mesenchymal stem cells (BMSCs) into hepatocyte-like cells (HLCs); however, the underlying mechanisms remain to be elucidated. The present study aimed to investigate this process. To do this, a dimethylnitrosamine (DMN)-induced liver cirrhosis mouse model was established. The mice from the model group were randomly divided into three subgroups: i) Negative control, ii) hepatocyte growth factor and iii) YGD. The overall health, liver function and histological alterations were monitored. The expression of α‑smooth muscle actin (α‑SMA), C‑X‑C chemokine receptor type 4 (CXCR4), extracellular signal‑regulated kinase (ERK1/2), nuclear factor κB p65 subunit (NF‑κB p65) and β‑catenin were measured by immunohistochemistry, western blotting and reverse transcription‑quantitative polymerase chain reaction. Following administration of DMN, the overall health of the mice significantly decreased, with an increase in pathological developments and liver damage resulting in a decrease in liver function. Immunohistochemistry revealed that the expression of α‑SMA, CXCR4, ERK1/2, NF‑κB p65 and β‑catenin was upregulated. Following treatment with YGD, the overall health, liver function and pathology improved. The mRNA and protein expression levels of CXCR4 and ERK1/2 were upregulated, where as α‑SMA, NF‑κB p65 and β‑catenin levels were downregulated. The results demonstrated that YGD may induce the differentiation of BMSCs into HLCs to reverse DMN‑induced liver cirrhosis; this may be achieved via an upregulation of the SDF‑1/CXCR4 axis to activate the mitogen activated protein kinase/ERK1/2 signaling pathway.

  9. Dietary choline deficiency and excess induced intestinal inflammation and alteration of intestinal tight junction protein transcription potentially by modulating NF-κB, STAT and p38 MAPK signaling molecules in juvenile Jian carp.

    PubMed

    Wu, Pei; Jiang, Wei-Dan; Jiang, Jun; Zhao, Juan; Liu, Yang; Zhang, Yong-An; Zhou, Xiao-Qiu; Feng, Lin

    2016-11-01

    This study investigated the effects of choline on intestinal mucosal immune and the possible mechanisms in fish by feeding juvenile Jian carp (Cyprinus carpio var. Jian) with graded levels of dietary choline (165-1820 mg/kg diet) for 65 days. The results firstly showed that choline deficiency induced inflammatory infiltration in the proximal intestine (PI), mid intestine (MI) and distal intestine (DI) of fish. Meanwhile, compared with the optimal choline group, choline deficiency decreased the activities of lysozyme and acid phosphatase, contents of complement 3 and IgM in the intestine, downregulated the mRNA levels of antimicrobial peptides (liver-expressed antimicrobial peptide (LEAP) 2A and defensin-3 in the PI and MI, LEAP-2B and hepcidin in the PI, MI and DI), anti-inflammatory cytokines (interleukin (IL) 10 and transforming growth factor β2 in the PI, MI and DI), and signaling molecule IκB in the PI, MI and DI; while upregulated the mRNA levels of pro-inflammatory cytokines (IL-6a and tumor necrosis factor α in the MI and DI, interferon γ2b in the PI and MI, IL-1β and IL-6b in the PI, MI and DI), and signaling molecules (Toll-like receptor 4 in the MI, myeloid differentiation primary response 88 in the PI and MI, Janus kinase 3 and tyrosine kinase 2 in the MI and DI, nuclear factor kappa B (NF-κB), signal transducers and activators of transcription (STAT) 4 and STAT5 in the PI, MI and DI) of juvenile Jian carp, further indicating that choline deficiency caused inflammation and immunity depression in the intestine of fish. But choline deficiency decreased the PI IL-6a mRNA level, and increased the DI LEAP-2A and defensin-3 mRNA levels with unknown reasons. Furthermore, dietary choline deficiency downregulated mRNA levels of tight junction (TJ) proteins (claudin 3c in the PI and MI, claudin 7, claudin 11 and occludin in the PI, MI and DI) and signaling molecule mitogen-activated protein kinases p38 in the PI, MI and DI of juvenile Jian carp, whereas

  10. Structural properties and thermodynamics of water clusters: a Wang-Landau study.

    PubMed

    Yin, Junqi; Landau, D P

    2011-02-21

    The temperature dependence of structural properties and thermodynamic behavior of water clusters has been studied using Wang-Landau sampling. Four potential models, simple point charge/extended (SPC/E), transferable intermolecular potential 3 point (TIP3P), transferable intermolecular potential 4 point (TIP4P), and Gaussian charge polarizable (GCP), are compared for ground states and properties at finite temperatures. Although the hydrogen bond energy and the distance of the nearest-neighbor oxygen pair are significantly different for TIP4P and GCP models, they approach to similar ground state structures and melting transition temperatures in cluster sizes we considered. Comparing with TIP3P, SPC/E model provides properties closer to that of TIP4P and GCP.

  11. Collapse transitions in a flexible homopolymer chain: application of the Wang-Landau algorithm.

    PubMed

    Seaton, D T; Wüst, T; Landau, D P

    2010-01-01

    The thermodynamic behavior of a continuous homopolymer is described using the Wang-Landau algorithm for chain lengths up to N=561. The coil-globule and liquid-solid transitions are analyzed in detail with traditional thermodynamic and structural quantities. The behavior of the coil-globule transition is well within theoretical and computational predictions for all chain lengths, while the behavior of the liquid-solid transition is much more susceptible to finite-size effects. Certain "magic number" lengths (N=13,55,147,309,561) , whose minimal energy states offer unique icosahedral geometries, are discussed along with chains residing between these special cases. The low temperature behavior near the liquid-solid transition is rich in structural transformations for certain chain lengths, showing many similarities to the behavior of classical clusters with similar interaction potentials. General comments are made on this size dependent behavior and how it affects transition behavior in this model.

  12. Characterizing folding funnels with replica exchange Wang-Landau simulation of lattice proteins.

    PubMed

    Shi, Guangjie; Wüst, Thomas; Landau, David P

    2016-11-01

    We have studied the folding of ribonuclease A by mapping it onto coarse-grained lattice protein models. With replica exchange Wang-Landau sampling, we calculated the free energy vs end-to-end distance as a function of temperature. A mapping to the famous hydrophobic-polar (HP) model shows a relatively shallow folding funnel and flat free energy minimum, reflecting the high degeneracy of the ground state. In contrast, extending the HP model with an additional "neutral" monomer type (i.e., a mapping to the three-letter H0P model) has a well developed, rough free energy funnel with a low degeneracy ground state. In both cases, folding funnels are asymmetric with temperature dependent shape.

  13. Replica-exchange Wang-Landau simulations of the H0P lattice protein model

    NASA Astrophysics Data System (ADS)

    Shi, Guangjie; Wüst, Thomas; Li, Ying Wai; Landau, David P.

    The hydrophobic-polar (HP) lattice protein model has been the subject of intensive investigation in an effort to aid our understanding of protein folding. However, the high ground state degeneracies caused by its simplification stands in contrast to the generally unique native states of natural proteins. Here we proposed a simple modification, by introducing a new type of ``neutral'' monomer, 0, i.e. neither hydrophobic nor polar, thus rendering the model more realistic without increasing the difficulties of sampling significantly. With the replica exchange Wang-Landau (REWL) scheme we investigated several widely studied HP proteins and their H0P counterparts. Dramatic differences in both ground state and thermodynamic properties have been found. For example, the H0P version of Crambin shows more clear two-step folding and 3 order of magnitudes less ground state degeneracy than its HP counterpart. Supported by NSF.

  14. Collapse transitions in a flexible homopolymer chain: Application of the Wang-Landau algorithm

    NASA Astrophysics Data System (ADS)

    Seaton, D. T.; Wüst, T.; Landau, D. P.

    2010-01-01

    The thermodynamic behavior of a continuous homopolymer is described using the Wang-Landau algorithm for chain lengths up to N=561 . The coil-globule and liquid-solid transitions are analyzed in detail with traditional thermodynamic and structural quantities. The behavior of the coil-globule transition is well within theoretical and computational predictions for all chain lengths, while the behavior of the liquid-solid transition is much more susceptible to finite-size effects. Certain “magic number” lengths (N=13,55,147,309,561) , whose minimal energy states offer unique icosahedral geometries, are discussed along with chains residing between these special cases. The low temperature behavior near the liquid-solid transition is rich in structural transformations for certain chain lengths, showing many similarities to the behavior of classical clusters with similar interaction potentials. General comments are made on this size dependent behavior and how it affects transition behavior in this model.

  15. Structural properties and thermodynamics of water clusters: A Wang-Landau study

    NASA Astrophysics Data System (ADS)

    Yin, Junqi; Landau, D. P.

    2011-02-01

    The temperature dependence of structural properties and thermodynamic behavior of water clusters has been studied using Wang-Landau sampling. Four potential models, simple point charge/extended (SPC/E), transferable intermolecular potential 3 point (TIP3P), transferable intermolecular potential 4 point (TIP4P), and Gaussian charge polarizable (GCP), are compared for ground states and properties at finite temperatures. Although the hydrogen bond energy and the distance of the nearest-neighbor oxygen pair are significantly different for TIP4P and GCP models, they approach to similar ground state structures and melting transition temperatures in cluster sizes we considered. Comparing with TIP3P, SPC/E model provides properties closer to that of TIP4P and GCP.

  16. Characterizing folding funnels with replica exchange Wang-Landau simulation of lattice proteins

    NASA Astrophysics Data System (ADS)

    Shi, Guangjie; Wüst, Thomas; Landau, David P.

    2016-11-01

    We have studied the folding of ribonuclease A by mapping it onto coarse-grained lattice protein models. With replica exchange Wang-Landau sampling, we calculated the free energy vs end-to-end distance as a function of temperature. A mapping to the famous hydrophobic-polar (HP) model shows a relatively shallow folding funnel and flat free energy minimum, reflecting the high degeneracy of the ground state. In contrast, extending the HP model with an additional "neutral" monomer type (i.e., a mapping to the three-letter H0P model) has a well developed, rough free energy funnel with a low degeneracy ground state. In both cases, folding funnels are asymmetric with temperature dependent shape.

  17. Surface adsorption of lattice HP proteins: Thermodynamics and structural transitions using Wang-Landau sampling

    NASA Astrophysics Data System (ADS)

    Li, Ying Wai; Wüst, Thomas; Landau, David P.

    2012-12-01

    Wang-Landau sampling has been applied to investigate the thermodynamics and structural properties of a lattice hydrophobic-polar heteropolymer (the HP protein model) interacting with an attractive substrate. For simplicity, we consider a short HP sequence consisting of only 36 monomers interacting with a substrate which attracts all monomers in the sequence. The conformational “phase transitions” have been identified by a canonical analysis of the specific heat and suitable structural observables. Three major “transitions”, namely, adsorption, hydrophobic core formation and “flattening” of adsorbed structures, are observed. Depending on the surface attractive strength relative to the intra-protein attraction among the H monomers, these processes take place in different sequences upon cooling.

  18. Wang-Landau sampling of protein adsorption using the HP model

    NASA Astrophysics Data System (ADS)

    Li, Ying-Wai; Landau, D. P.; Wuest, T.

    2011-03-01

    We have applied Wang-Landau sampling with appropriate trial moves to investigate the thermodynamics and structural properties of lattice hydrophobic-polar heteropolymers (commonly known as the HP protein model) interacting with an attractive substrate. We estimate the density of states of the system, from which the partition function and all thermodynamic quantities, e.g. specific heat, radius of gyration, end-to-end distance and surface contacts, can be calculated. ``Transitions'' between ``phases'' are then identified based on a comprehensive analysis of these observables. Generally speaking, three transition processes are observed: adsorption-desorption, collapse (formation of hydrophobic core), and ``flattening'' of adsorbed structures. These have been confirmed by ``snapshots'' of typical states of the system. Depending on the surface attractive strength, these transitions take place in different order upon cooling, giving rise to different thermodynamic behaviors. Such dependence of folding hierarchy on the surface attraction is found to be universal for different HP sequences. Research supported by NSF.

  19. Protective Effect of Tang Wang One Decoction on the Retinal Vessels of Diabetic Rats

    PubMed Central

    Kou, Xinyun; Yang, Shufei; Qin, Yali; Yang, Chao; Deng, Tingting; Luo, Dan

    2017-01-01

    Objective. This study aimed to determine the influence of Tang Wang One Decoction (TWOD) on the retinal vessels of diabetic rats. Methods. The hemorheology of diabetic rats was observed. Morphological studies of retinal vessels were conducted using optical microscopy and electron microscopy. Immunological histochemistry assay was used to measure the expression levels of MMP-9, occludin, and claudin-5. Results. Obvious pathological damage was observed in the retinal vessels of diabetic rats. TWOD positively affected the hemorheology and morphology of retinal vessels. The decoction also decreased the expression of MMP-9 and increased the expression of occludin and claudin-5. Conclusions. The results suggest that the retinal protective effects of TWOD might be related to downregulation of MMP-9 and upregulation of occludin and claudin-5. PMID:28367226

  20. [RAPD and SCAR molecular markers linked to the sexuality of cycads (Cycas tanqingii D. Y. Wang)].

    PubMed

    Jing, Jian-Zhou; Jin, Hong; Li, Dong-Liang; Chen, Xiao-Ke; Zhang, Yong

    2007-11-01

    The random amplified polymorphic DNA (RAPD) technique was used to amplify DNA fragment, aiming at finding markers linked to the sex trait in Cycas tanqingii D. Y. Wang. A total number of 160 random primers were screened in the RAPD-PCR and more than 2500 RAPD fragments were generated from the male or the female plants. One fragment of about 500 bp was amplified steadily and repeatedly by the S0465 (CCCCGGTAAC) primer only from female plants but not male plants. The RAPD marker was then converted into female-linked dominant SCAR (Sequence Characterized Amplified Regions) marker named STQC-S465-483. The development of this sex-linked SCAR marker provides a possibility of identifying the sex of Cycas tanqingii before sexual maturation, which is very important to in situ or ex situ conservation.

  1. Thermodynamics and structural properties of a confined HP protein determined by Wang-Landau simulation

    SciTech Connect

    Pattanasiri, Busara; Li, Ying Wai; Landau, David P; Wuest, Thomas; Triampo, Wannapong

    2013-01-01

    We used Wang-Landau sampling with inventive Monte Carlo moves to study the influence of surface characteristics on physical behavior of a hydrophobic-polar (HP) lattice protein model confined between two attractive surfaces. Three types of surfaces, namely, surfaces that attract: (a) all monomers; (b) only P monomers; or (c) only H monomers, have been considered. After obtaining the densities of states, we then found the thermodynamic and structural quantities, such as specific heat, number of surface contacts, and number of hydrophobic interaction pairs. A few conformational transitions , e.g., debridging process and hydrophobic core formation, can be identified based on an analysis of these quantities. Depending on the surface types, these transitions take place at different temperatures, while the ground state configurations show structural variations. These scenarios are confirmed by snapshots of typical states of the systems.

  2. OpenACC programs of the Swendsen-Wang multi-cluster spin flip algorithm

    NASA Astrophysics Data System (ADS)

    Komura, Yukihiro

    2015-12-01

    We present sample OpenACC programs of the Swendsen-Wang multi-cluster spin flip algorithm. OpenACC is a directive-based programming model for accelerators without requiring modification to the underlying CPU code itself. In this paper, we deal with the classical spin models as with the sample CUDA programs (Komura and Okabe, 2014), that is, two-dimensional (2D) Ising model, three-dimensional (3D) Ising model, 2D Potts model, 3D Potts model, 2D XY model and 3D XY model. We explain the details of sample OpenACC programs and compare the performance of the present OpenACC implementations with that of the CUDA implementations for the 2D and 3D Ising models and the 2D and 3D XY models.

  3. First principles finite temperature magnetism of defects in Fe using Wang-Landau method

    NASA Astrophysics Data System (ADS)

    Rusanu, Aurelian; Nicholson, D. M.; Odbadrakh, Kh.; Brown, Gregory; Eisenbach, Markus

    2011-03-01

    Magnetic structure of materials with defects presents a strong dependence on local atomic arrangements. This dependence affects mechanical, magneto-caloric, and magnetization properties. Insights into thermodynamic and magnetic fluctuations at defects in Fe are obtained from first principle analysis by deploying the first principle local self consistent multiple scattering method(LSMS) and Wang-Landau statistical method. The computation of thermodynamic properties requires the sampling of a large number of configurations. To reduce the computational effort a Heisenberg model will be used to speed the configuration sampling procedures. The approach will be demonstrated for Fe systems and will address the magnetic structure of defects. This work was supported by the Center for Defect Physics, an Energy Frontier Research Center funded by the US DoE, Office of Science, Office of Basic Energy Sciences. Calculations performed at the National Center for Computational Sciences.

  4. Why Three Heads Are a Better Bet than Four: A Reply to Sun, Tweney, and Wang (2010)

    ERIC Educational Resources Information Center

    Hahn, Ulrike; Warren, Paul A.

    2010-01-01

    We (Hahn & Warren, 2009) recently proposed a new account of the systematic errors and biases that appear to be present in people's perception of randomly generated events. In a comment on that article, Sun, Tweney, and Wang (2010) critiqued our treatment of the gambler's fallacy. We had argued that this fallacy was less gross an error than it…

  5. Effect of Jian-Pi-Zhi-Dong Decoction on striatal glutamate and γ-aminobutyric acid levels detected using microdialysis in a rat model of Tourette syndrome

    PubMed Central

    Zhang, Wen; Wei, Li; Yu, Wenjing; Cui, Xia; Liu, Xiaofang; Wang, Qian; Wang, Sumei

    2016-01-01

    Background Jian-Pi-Zhi-Dong Decoction (JPZDD) is a dedicated treatment of Tourette syndrome (TS). The balance of neurotransmitters in the cortico-striato-pallido-thalamo-cortical network is crucial to the occurrence of TS and related to its severity. This study evaluated the effect of JPZDD on glutamate (Glu) and γ-aminobutyric acid (GABA) and their receptors in a TS rat model. Materials and methods Rats were divided into four groups (n=12 each). TS was induced in three of the groups by injecting them with 3,3′-iminodipropionitrile for 7 consecutive days. Two model groups were treated with tiapride (Tia) or JPZDD, while the control and the remaining model group were gavaged with saline. Behavior was assessed by stereotypic score and autonomic activity. Striatal Glu and GABA contents were detected using microdialysis. Expressions of N-methyl-D-aspartate receptor 1 and GABAA receptor (GABAAR) were observed using Western blot and real-time polymerase chain reaction. Results Tia and JPZDD groups had decreased stereotypy compared with model rats; however, the JPZDD group showed a larger decrease in stereotypy than the Tia group at a 4-week time point. In a spontaneous activity test, the total distance of the JPZDD and Tia groups was significantly decreased compared with the model group. The Glu levels of the model group were higher than the control group and decreased with Tia or JPZDD treatment. The GABA level was higher in the model group than the control group. Expressions of GABAAR protein in the model group were higher than in the control group. Treatment with Tia or JPZDD reduced the expression of GABAAR protein. In the case of the mRNA expression, only Tia reduced the expression of N-methyl-D-aspartate receptor 1, compared with the model group. Conclusion JPZDD could alleviate impairments in behavior and dysfunctional signaling by downregulating GABAAR in the striatum. We suggest that this acts to maintain the balance of Glu and GABA. PMID:27279743

  6. Anti-tumor activity of Sann-Joong-Kuey-Jian-Tang alone and in combination with 5-fluorouracil in a human colon cancer colo 205 cell xenograft model.

    PubMed

    Cheng, Chun-Yuan; Lin, Yi-Hsiang; Su, Chin-Cheng

    2010-01-01

    Malignant tumors are the leading cause of death in Taiwan; among these, colon cancer ranks third as a cause of cancer-related death. Sann-Joong-Kuey-Jian-Tang (SJKJT), a traditional Chinese medicinal prescription, has been used to treat lymph node diseases and infectious lesions, and exhibits cytotoxic activity in many cancer cell lines. Our previous studies demonstrated that SJKJT inhibits the proliferation of human colon cancer colo 205 cells in vitro. The aim of this study was to evaluate the anti-tumor activity of SJKJT alone and in combination with 5-fluorouracil (5-FU) in vivo. SCID mice bearing human colon cancer colo 205 cell xenografts were administered SJKJT alone (30 mg/kg daily, p.o.), SJKJT (30 mg/kg daily, p.o.) in combination with 5-FU (30 mg/kg weekly, i.p.), or vehicle alone. At the end of the 4-week dosing schedule, the tumor and animal body weights were individually measured. The SCID mice were sacrificed with CO2 inhalation, the xenograft tumors were dissected, and the protein expression of microtubule-associated protein light chain 3 (MAP-LC3-II) in colo 205 xenograft tumors was measured by Western blotting. In the control, SJKJT-, and SJKJT plus 5-FU-treated mice, the tumor weights were 6.37±2.57, 0.43±0.35 and 1.63±0.46 g, and the mice body weights were 29±0.55, 29±2.71 and 27±0.77 g, respectively. Treatment with SJKJT resulted in a reduction in tumor weight compared with the control group, indicating that SJKJT inhibits tumor growth in a colo 205 xenograft model. SJKJT also increased LC3-II protein expression as compared to the controls. The present study shows that SJKJT alone or in combination with 5-FU has a positive effect on the treatment of SCID mice bearing human colon cancer colo 205 cell xenografts. This suggests that SJKJT has therapeutic potential in the treatment of human colon cancer.

  7. Generic transition hierarchies of lattice HP protein adsorption: A Wang-Landau study

    NASA Astrophysics Data System (ADS)

    Li, Ying Wai; Landau, D. P.; Wüst, T.

    2012-02-01

    We have applied Wang-Landau sampling with appropriate trial movesootnotetextT. W"ust and D. P. Landau, Phy. Rev. Lett. 102, 178101 (2009). to investigate the thermodynamics and structural properties of the HP lattice protein modelootnotetextK. A. Dill, Biochemistry 24, 1501 (1985). interacting with an attractive substrate. The conformational ``phase transitions'' of several benchmark HP sequences have been identified by a comprehensive canonical analysis of the specific heat and structural observables, e. g. radius of gyration and thermal derivatives of number of surface contacts. Three major ``transitions'': adsorption, hydrophobic core formation, and ``flattening'' of adsorbed structures, are observed. Depending on the surface attractive strength relative to the intra-protein attraction among the H monomers, these processes take place in a different order upon cooling. We identify a small number of generic categories that are sufficient to classify the folding hierarchies for different HP chains consisting of assorted sequences and chain lengths, regardless of the monomer type that the surface attracts. We thus believe that this classification scheme is generally applicable to lattice protein adsorption problems.

  8. Thermodynamics and structural properties of a confined HP protein determined by Wang-Landau simulation

    NASA Astrophysics Data System (ADS)

    Pattanasiri, Busara; Li, Ying Wai; Landau, David P.; Wüst, Thomas; Triampo, Wannapong

    2013-08-01

    Understanding protein folding confined by surfaces is important for both biological sciences and the development of nanomaterials. In this work, we study the properties of a confined HP model protein by three different types of surfaces, namely, surfaces that attract: (a) all monomers; (b) only P monomers; and (c) only H monomers. The thermodynamic and structural quantities, such as the specific heat, number of surface contacts, and number of hydrophobic pairs, are obtained by using Wang-Landau sampling. The conformational "transitions", specifically, the debridging process and hydrophobic core formation, can be identified based on an analysis of these quantities. We found that these transitions take place at different temperatures, and the ground state configurations show variations in structural properties when different surface type is used. These scenarios are confirmed by snapshots of typical states of the systems. From our study, we conclude that the thermodynamics of these transitions and the structural changes depend on the combined actions of both the composition of the H monomers and the P monomers in the HP chain and the surface types.

  9. Application of the Wang-Landau algorithm to the dimerization of glycophorin A

    NASA Astrophysics Data System (ADS)

    Gervais, Claire; Wüst, Thomas; Landau, D. P.; Xu, Ying

    2009-06-01

    A two-step Monte Carlo procedure is developed to investigate the dimerization process of the homodimer glycophorin A. In the first step, the energy density of states of the system is estimated by the Wang-Landau algorithm. In the second step, a production run is performed during which various energetical and structural observables are sampled to provide insight into the thermodynamics of the system. All seven residues LIxxGVxxGVxxT constituting the contact interface play a dominating role in the dimerization, however at different stages of the process. The leucine motif and to some extent the GxxxG motif are involved at the very beginning of the dimerization when the two helices come into contact, ensuring an interface already similar to the native one. At a lower temperature, the threonine motif stabilizes by hydrogen bonding the dimer, which finally converges toward its native state at around 300 K. The power and flexibility of the procedure employed here makes it an interesting alternative to other Monte Carlo methods for the study of similar protein systems.

  10. Wang-Landau sampling of the interplay between surface adsorption and folding of HP lattice proteins

    SciTech Connect

    Li, Ying Wai; Wuest, Thomas; Landau, David P

    2014-01-01

    Generic features associated with the adsorption of proteins on solid surfaces are reviewed within the framework of the hydrophobic-polar (HP) lattice protein model. The thermodynamic behavior and structural properties of various HP protein sequences interacting with attractive surfaces have been studied using extensive Wang-Landau sampling with different types of surfaces, each of which attracts either: all monomers, only hydrophobic (H) monomers, or only polar (P) monomers, respectively. Consequently, different types of folding behavior occur for varied surface strengths. Analysis of the combined patterns of various structural observables, e.g., the derivatives of the numbers of interaction contacts, together with the specific heat, leads to the identification of fundamental categories of folding and transition hierarchies. We also inferred a connection between the transition categories and the relative surface strengths, i.e., the ratios of the surface attractive strengths to the intra-chain attraction among H monomers. We thus believe that the folding hierarchies and identification scheme are generic for different HP sequences interacting with attractive surfaces, regardless of the chain length, sequence, or surface attraction.

  11. Temperature-dependent phase transition of ferroelectric perovskites: A Wang-Landau-DFT approach

    NASA Astrophysics Data System (ADS)

    Yuk, Simuck; Li, Ying Wai; Eisenbach, Markus; Cooper, Valentino

    Since the discovery of ferroelectricity in perovskite oxides, considerable efforts have been devoted to understanding their phase transition behaviors in terms of temperature, pressure, and composition. Such materials have regularly been used in transducer and actuator applications. As our first step to make accurate predictions of the crystal phases of more complex oxides such as Pb(ZrxTi1-x) O3, we have used the Wang-Landau (WL) algorithm and density functional theory (DFT) to examine the temperature-dependent phase transition of PbTiO3, BaTiO3, and KNbO3. DFT was employed to evaluate the energetics of important crystal-structure candidates, which were later used as the input for WL algorithm. In addition, we examine how the choice of exchange-correlation functionals affects our predictions of the relevant phase transition temperatures. Research supported by the U.S. Department of Energy, Office of Science, Basic Energy Sciences, Materials Science and Engineering Division and the Office of Science Early Career Research Program (V.R.C.) and used resources at NERSC and OLCF.

  12. Somatic embryogenesis and enhanced shoot organogenesis in Metabriggsia ovalifolia W. T. Wang

    PubMed Central

    Ouyang, Yao; Chen, Yulu; Lü, Jinfeng; Teixeira da Silva, Jaime A.; Zhang, Xinhua; Ma, Guohua

    2016-01-01

    An efficient protocol providing a dual regeneration pathway via direct shoot organogenesis and somatic embryogenesis for an endangered species, Metabriggsia ovalifolia W. T. Wang, was established from leaf explants. When applied at 2.5 μM, the cytokinins 6-benzyladenine (BA) or thidiazuron (TDZ) and the auxins indole-3-butyric acid (IBA), α-naphthaleneacetic acid (NAA) and indole-3-acetic acid (IAA) could induce shoots when on basal Murashige and Skoog (MS) medium. BA and TDZ could induce more adventitious shoots (19.1 and 31.2/explant, respectively) than NAA (4.6/explant), IBA (5.7/explant) or IAA (6.4/explant). BA and TDZ at 5–10 μM could induce both shoots and somatic embryos. A higher concentration of TDZ (25 μM) induced only somatic embryos (39.8/explant). The same concentration of BA induced both adventitious shoots (23.6/explant) and somatic embryos (9.7/explant). Thus, somatic embryogenesis in this plant needs a high cytokinin concentration (BA; TDZ), as evidenced by histology. Somatic embryos germinated easily when left on the same media, but formed adventitious roots in two weeks on MS supplemented with 0.5 μM NAA, 0.5 μM IBA and 0.1% activated charcoal. Over 93% of plantlets survived following acclimatization and transfer to a mixture of sand and vermiculite (1:1, v/v) in trays. PMID:27090564

  13. Phase transitions of a single polymer chain: A Wang-Landau simulation study.

    PubMed

    Taylor, Mark P; Paul, Wolfgang; Binder, Kurt

    2009-09-21

    A single flexible homopolymer chain can assume a variety of conformations which can be broadly classified as expanded coil, collapsed globule, and compact crystallite. Here we study transitions between these conformational states for an interaction-site polymer chain comprised of N=128 square-well-sphere monomers with hard-sphere diameter sigma and square-well diameter lambdasigma. Wang-Landau sampling with bond-rebridging Monte Carlo moves is used to compute the density of states for this chain and both canonical and microcanonical analyses are used to identify and characterize phase transitions in this finite size system. The temperature-interaction range (i.e., T-lambda) phase diagram is constructed for lambda1.06 these two states are separated by an intervening collapsed globule phase and thus, with decreasing temperature a chain undergoes a continuous coil-globule (collapse) transition followed by a discontinuous globule-crystal (freezing) transition. For well diameters lambda<1.06 the collapse transition is pre-empted by the freezing transition and thus there is a direct first-order coil-crystal phase transition. These results confirm the recent prediction, based on a lattice polymer model, that a collapsed globule state is unstable with respect to a solid phase for flexible polymers with sufficiently short-range monomer-monomer interactions.

  14. Somatic embryogenesis and enhanced shoot organogenesis in Metabriggsia ovalifolia W. T. Wang.

    PubMed

    Ouyang, Yao; Chen, Yulu; Lü, Jinfeng; Teixeira da Silva, Jaime A; Zhang, Xinhua; Ma, Guohua

    2016-04-19

    An efficient protocol providing a dual regeneration pathway via direct shoot organogenesis and somatic embryogenesis for an endangered species, Metabriggsia ovalifolia W. T. Wang, was established from leaf explants. When applied at 2.5 μM, the cytokinins 6-benzyladenine (BA) or thidiazuron (TDZ) and the auxins indole-3-butyric acid (IBA), α-naphthaleneacetic acid (NAA) and indole-3-acetic acid (IAA) could induce shoots when on basal Murashige and Skoog (MS) medium. BA and TDZ could induce more adventitious shoots (19.1 and 31.2/explant, respectively) than NAA (4.6/explant), IBA (5.7/explant) or IAA (6.4/explant). BA and TDZ at 5-10 μM could induce both shoots and somatic embryos. A higher concentration of TDZ (25 μM) induced only somatic embryos (39.8/explant). The same concentration of BA induced both adventitious shoots (23.6/explant) and somatic embryos (9.7/explant). Thus, somatic embryogenesis in this plant needs a high cytokinin concentration (BA; TDZ), as evidenced by histology. Somatic embryos germinated easily when left on the same media, but formed adventitious roots in two weeks on MS supplemented with 0.5 μM NAA, 0.5 μM IBA and 0.1% activated charcoal. Over 93% of plantlets survived following acclimatization and transfer to a mixture of sand and vermiculite (1:1, v/v) in trays.

  15. Nonconvergence of the Wang-Landau algorithms with multiple random walkers.

    PubMed

    Belardinelli, R E; Pereyra, V D

    2016-05-01

    This paper discusses some convergence properties in the entropic sampling Monte Carlo methods with multiple random walkers, particularly in the Wang-Landau (WL) and 1/t algorithms. The classical algorithms are modified by the use of m-independent random walkers in the energy landscape to calculate the density of states (DOS). The Ising model is used to show the convergence properties in the calculation of the DOS, as well as the critical temperature, while the calculation of the number π by multiple dimensional integration is used in the continuum approximation. In each case, the error is obtained separately for each walker at a fixed time, t; then, the average over m walkers is performed. It is observed that the error goes as 1/sqrt[m]. However, if the number of walkers increases above a certain critical value m>m_{x}, the error reaches a constant value (i.e., it saturates). This occurs for both algorithms; however, it is shown that for a given system, the 1/t algorithm is more efficient and accurate than the similar version of the WL algorithm. It follows that it makes no sense to increase the number of walkers above a critical value m_{x}, since it does not reduce the error in the calculation. Therefore, the number of walkers does not guarantee convergence.

  16. Influence of yield on in vitro accumulation of aflatoxins in pecan (Carya illinoensis (Wang.) K. Koch) nutmeats.

    PubMed Central

    McMeans, J L

    1983-01-01

    Pecans were harvested from trees (Carya illinoensis (Wang.) K. Koch) in November of 1977 through 1979. Kernel meals from high-, medium-, and low-yielding trees were inoculated with a spore suspension of Aspergillus parasiticus and incubated for 7 days at 25 degrees C. Significant differences in aflatoxin accumulation were found among the three substrates, with a direct correlation between high aflatoxin concentration and tree yield. PMID:6830223

  17. Influence of yield on in vitro accumulation of aflatoxins in pecan (Carya illinoensis (Wang.) K. Koch) nutmeats.

    PubMed

    McMeans, J L

    1983-02-01

    Pecans were harvested from trees (Carya illinoensis (Wang.) K. Koch) in November of 1977 through 1979. Kernel meals from high-, medium-, and low-yielding trees were inoculated with a spore suspension of Aspergillus parasiticus and incubated for 7 days at 25 degrees C. Significant differences in aflatoxin accumulation were found among the three substrates, with a direct correlation between high aflatoxin concentration and tree yield.

  18. Monte Carlo and Molecular Dynamics in the Multicanonical Ensemble: Connections between Wang-Landau Sampling and Metadynamics

    NASA Astrophysics Data System (ADS)

    Vogel, Thomas; Perez, Danny; Junghans, Christoph

    2014-03-01

    We show direct formal relationships between the Wang-Landau iteration [PRL 86, 2050 (2001)], metadynamics [PNAS 99, 12562 (2002)] and statistical temperature molecular dynamics [PRL 97, 050601 (2006)], the major Monte Carlo and molecular dynamics work horses for sampling from a generalized, multicanonical ensemble. We aim at helping to consolidate the developments in the different areas by indicating how methodological advancements can be transferred in a straightforward way, avoiding the parallel, largely independent, developments tracks observed in the past.

  19. A description of preimaginal stages of Pseudaspidapion botanicum Alonso-Zarazaga & Wang, 2011 (Apionidae, Curculionoidea)

    PubMed Central

    Wang, Zhiliang; Alonso-Zarazaga, M. A.; Zhou, Dakang; Zhang, Runzhi

    2013-01-01

    Abstract The preimaginal stages including egg, mature larva and pupa of Pseudaspidapion botanicum Alonso-Zarazaga & Wang, 2011 were described and figured, diagnostic characters of larva and pupa were discussed, and corresponding biological information was supplied. The nomenclature of frontal setae in the larva compared with curculionid weevils, the absence of the hypopharyngeal bracon in the larva, and the metafemoral setae in the pupa were discussed. Common and different characters among the larvae of Pseudaspidapion botanicum, Aspidapion radiolus (Marsham, 1802) and Aspidapion aeneum (Fabricius, 1775) were also provided. PMID:23653504

  20. Critical endpoint behavior in an asymmetric Ising model: application of Wang-Landau sampling to calculate the density of states.

    PubMed

    Tsai, Shan-Ho; Wang, Fugao; Landau, D P

    2007-06-01

    Using the Wang-Landau sampling method with a two-dimensional random walk we determine the density of states for an asymmetric Ising model with two- and three-body interactions on a triangular lattice, in the presence of an external field. With an accurate density of states we were able to map out the phase diagram accurately and perform quantitative finite-size analyses at, and away from, the critical endpoint. We observe a clear divergence of the curvature of the spectator phase boundary and of the magnetization coexistence diameter derivative at the critical endpoint, and the exponents for both divergences agree well with previous theoretical predictions.

  1. Critical endpoint behavior in an asymmetric Ising model: Application of Wang-Landau sampling to calculate the density of states

    NASA Astrophysics Data System (ADS)

    Tsai, Shan-Ho; Wang, Fugao; Landau, D. P.

    2007-06-01

    Using the Wang-Landau sampling method with a two-dimensional random walk we determine the density of states for an asymmetric Ising model with two- and three-body interactions on a triangular lattice, in the presence of an external field. With an accurate density of states we were able to map out the phase diagram accurately and perform quantitative finite-size analyses at, and away from, the critical endpoint. We observe a clear divergence of the curvature of the spectator phase boundary and of the magnetization coexistence diameter derivative at the critical endpoint, and the exponents for both divergences agree well with previous theoretical predictions.

  2. Calculation of the Curie temperature of Ni using first principles based Wang-Landau Monte-Carlo

    NASA Astrophysics Data System (ADS)

    Eisenbach, Markus; Yin, Junqi; Li, Ying Wai; Nicholson, Don

    2015-03-01

    We combine constrained first principles density functional with a Wang-Landau Monte Carlo algorithm to calculate the Curie temperature of Ni. Mapping the magnetic interactions in Ni onto a Heisenberg like model to underestimates the Curie temperature. Using a model we show that the addition of the magnitude of the local magnetic moments can account for the difference in the calculated Curie temperature. For ab initio calculations, we have extended our Locally Selfconsistent Multiple Scattering (LSMS) code to constrain the magnitude of the local moments in addition to their direction and apply the Replica Exchange Wang-Landau method to sample the larger phase space efficiently to investigate Ni where the fluctuation in the magnitude of the local magnetic moments is of importance equal to their directional fluctuations. We will present our results for Ni where we compare calculations that consider only the moment directions and those including fluctuations of the magnetic moment magnitude on the Curie temperature. This research was sponsored by the Department of Energy, Offices of Basic Energy Science and Advanced Computing. We used Oak Ridge Leadership Computing Facility resources at Oak Ridge National Laboratory, supported by US DOE under contract DE-AC05-00OR22725.

  3. Three-Dimensional MHD Modeling of The Solar Corona and Solar Wind: Comparison with The Wang-Sheeley Model

    NASA Technical Reports Server (NTRS)

    Usmanov, A. V.; Goldstein, M. L.

    2003-01-01

    We present simulation results from a tilted-dipole steady-state MHD model of the solar corona and solar wind and compare the output from our model with the Wang-Sheeley model which relates the divergence rate of magnetic flux tubes near the Sun (inferred from solar magnetograms) to the solar wind speed observed near Earth and at Ulysses. The boundary conditions in our model specified at the coronal base and our simulation region extends out to 10 AU. We assumed that a flux of Alfven waves with amplitude of 35 km per second emanates from the Sun and provides additional heating and acceleration for the coronal outflow in the open field regions. The waves are treated in the WKB approximation. The incorporation of wave acceleration allows us to reproduce the fast wind measurements obtained by Ulysses, while preserving reasonable agreement with plasma densities typically found at the coronal base. We find that our simulation results agree well with Wang and Sheeley's empirical model.

  4. Multi-GPU-based Swendsen-Wang multi-cluster algorithm for the simulation of two-dimensional q-state Potts model

    NASA Astrophysics Data System (ADS)

    Komura, Yukihiro; Okabe, Yutaka

    2013-01-01

    We present multiple GPU computing with the common unified device architecture (CUDA) for the Swendsen-Wang multi-cluster algorithm of two-dimensional (2D) q-state Potts model. Extending our algorithm for single GPU computing [Y. Komura, Y. Okabe, GPU-based Swendsen-Wang multi-cluster algorithm for the simulation of two-dimensional classical spin systems, Comput. Phys. Comm. 183 (2012) 1155-1161], we realize the GPU computation of the Swendsen-Wang multi-cluster algorithm for multiple GPUs. We implement our code on the large-scale open science supercomputer TSUBAME 2.0, and test the performance and the scalability of the simulation of the 2D Potts model. The performance on Tesla M2050 using 256 GPUs is obtained as 37.3 spin flips per a nano second for the q=2 Potts model (Ising model) at the critical temperature with the linear system size L=65536.

  5. All-atom simulation study of protein PTH(1-34) by using the Wang-Landau sampling method

    NASA Astrophysics Data System (ADS)

    Kim, Seung-Yeon; Kwak, Wooseop

    2014-12-01

    We perform simulations of the N-terminal 34-residue protein fragment PTH(1-34), consisting of 581 atoms, of the 84-residue human parathyroid hormone by using the all-atom ECEPP/3 force field and the Wang-Landau sampling method. Through a massive high-performance computation, the density of states and the partition function Z( T), as a continuous function of T, are obtained for PTH(1-34). From the continuous partition function Z( T), the partition function zeros of PTH(1-34) are evaluated for the first time. From both the specific heat and the partition function zeros, two characteristic transition temperatures are obtained for the all-atom protein PTH(1-34). The higher transition temperature T 1 and the lower transition temperature T 2 of PTH(1-34) can be interpreted as the collapse temperature T θ and the folding temperature T f , respectively.

  6. Magnetic phase transition in coupled spin-lattice systems: A replica-exchange Wang-Landau study.

    PubMed

    Perera, Dilina; Vogel, Thomas; Landau, David P

    2016-10-01

    Coupled, dynamical spin-lattice models provide a unique test ground for simulations investigating the finite-temperature magnetic properties of materials under the direct influence of the lattice vibrations. These models are constructed by combining a coordinate-dependent interatomic potential with a Heisenberg-like spin Hamiltonian, facilitating the treatment of both the atomic coordinates and the spins as explicit phase variables. Using a model parameterized for bcc iron, we study the magnetic phase transition in these complex systems via the recently introduced, massively parallel replica-exchange Wang-Landau Monte Carlo method. Comparison with the results obtained from rigid lattice (spin-only) simulations shows that the transition temperature as well as the amplitude of the peak in the specific heat curve is marginally affected by the lattice vibrations. Moreover, the results were found to be sensitive to the particular choice of interatomic potential.

  7. Magnetic phase transition in coupled spin-lattice systems: A replica-exchange Wang-Landau study

    NASA Astrophysics Data System (ADS)

    Perera, Dilina; Vogel, Thomas; Landau, David P.

    2016-10-01

    Coupled, dynamical spin-lattice models provide a unique test ground for simulations investigating the finite-temperature magnetic properties of materials under the direct influence of the lattice vibrations. These models are constructed by combining a coordinate-dependent interatomic potential with a Heisenberg-like spin Hamiltonian, facilitating the treatment of both the atomic coordinates and the spins as explicit phase variables. Using a model parameterized for bcc iron, we study the magnetic phase transition in these complex systems via the recently introduced, massively parallel replica-exchange Wang-Landau Monte Carlo method. Comparison with the results obtained from rigid lattice (spin-only) simulations shows that the transition temperature as well as the amplitude of the peak in the specific heat curve is marginally affected by the lattice vibrations. Moreover, the results were found to be sensitive to the particular choice of interatomic potential.

  8. Wang-Landau method for calculating Rényi entropies in finite-temperature quantum Monte Carlo simulations.

    PubMed

    Inglis, Stephen; Melko, Roger G

    2013-01-01

    We implement a Wang-Landau sampling technique in quantum Monte Carlo (QMC) simulations for the purpose of calculating the Rényi entanglement entropies and associated mutual information. The algorithm converges an estimate for an analog to the density of states for stochastic series expansion QMC, allowing a direct calculation of Rényi entropies without explicit thermodynamic integration. We benchmark results for the mutual information on two-dimensional (2D) isotropic and anisotropic Heisenberg models, a 2D transverse field Ising model, and a three-dimensional Heisenberg model, confirming a critical scaling of the mutual information in cases with a finite-temperature transition. We discuss the benefits and limitations of broad sampling techniques compared to standard importance sampling methods.

  9. LETTER TO THE EDITOR: Coarsening in the 1D Ising model evolving with Swendsen - Wang dynamics: an unusual scaling

    NASA Astrophysics Data System (ADS)

    Derrida, Bernard; Hakim, Vincent

    1996-12-01

    We consider a simple model of domain growth: the zero-temperature 1D Ising model evolving according to the Swendsen - Wang dynamics. We find that in the long-time limit, the pair correlation function scales with a characteristic length increasing as the square of the average domain size. In that limit, a few large domains occupy almost all the space with many small domains between them. In contrast to the usual picture of coarsening, the average domain size here is not a characteristic length of the growth problem. Instead, one finds a power-law distribution for the sizes of large domains with a cut-off at a length which grows as the square of the average size of the domains.

  10. Two Simple Approaches to Overcome a Problem with the Mantel-Haenszel Statistic: Comments on Wang, Bradlow, Wainer, and Muller (2008)

    ERIC Educational Resources Information Center

    Sinharay, Sandip; Dorans, Neil J.

    2010-01-01

    The Mantel-Haenszel (MH) procedure (Mantel and Haenszel) is a popular method for estimating and testing a common two-factor association parameter in a 2 x 2 x K table. Holland and Holland and Thayer described how to use the procedure to detect differential item functioning (DIF) for tests with dichotomously scored items. Wang, Bradlow, Wainer, and…

  11. Sann-Joong-Kuey-Jian-Tang decreases the protein expression of Mcl‑1 and TCTP and increases that of TNF-α and Bax in BxPC‑3 pancreatic carcinoma cells.

    PubMed

    Chien, Su-Yu; Kuo, Shou-Jen; Chen, Dar-Ren; Su, Chin-Cheng

    2013-07-01

    Sann-Joong-Kuey-Jian-Tang (SJKJT), a traditional Chinese medicinal prescription, has been used for the treatment of lymphadenopathy and solid tumors, and has shown therapeutic potential in several human malignant tumor cell lines. However, the efficacy and molecular mechanisms of action of SJKJT in human pancreatic cancer have not yet been elucidated. In the present study, we evaluated the cytotoxic effects of SJKJT on BxPC-3 human pancreatic carcinoma cells by MTT assay. The protein expression levels of myeloid cell leukemia 1 protein (Mcl-1), translationally controlled tumor protein (TCTP), tumor necrosis factor-α (TNF‑α), caspase-8, caspase-3, Bax and Bcl-2 family in the BxPC-3 cells were measured by western blot analysis. The cell cycle was analyzed by flow cytometry. The protein expression of caspase-3 was also detected by immunocytochemistry (ICC). The results revealed that SJKJT inhibited the proliferation of BxPC-3 cells in a time- and dose-dependent manner. The protein expression levels of TNF-α, caspase-8, caspase-3 and Bax increased in the BxPC-3 cells treated with SJKJT; however, the levels of Mcl-1, TCTP and Bcl-xL decreased. The results also demonstrated that SJKJT increased the percentage of BxPC-3 cells in the sub-G1 phase. In addition, ICC staining indicated that the protein expression of caspase-3 was upregulated in the BxPC-3 cells treated with SJKJT. These findings indicate that SJKJT inhibits the proliferation of BxPC-3 cells through the extrinsic and intrinsic pathway, inducing apoptosis in vitro. Our study, using BxPC-3 human pancreatic cancer cells, demonstrates that SJKJT has potential as a chemotherapeutic agent for the treatment of pancreatic cancer. Further sutdies are warranted to fully elucidate its mechanisms of action.

  12. Sann-Joong-Kuey-Jian-Tang induces autophagy in HepG2 cells via regulation of the phosphoinositide-3 kinase/Akt/mammalian target of rapamycin and p38 mitogen-activated protein kinase pathways.

    PubMed

    Chuang, Wan-Ling; Su, Chin-Cheng; Lin, Ping-Yi; Lin, Chi-Chen; Chen, Yao-Li

    2015-08-01

    Sann-Joong-Kuey-Jian-Tang (SJKJT), a traditional Chinese medicine, was previously reported to induce autophagy and inhibit the proliferation of the human HepG2 hepatocellular carcinoma cell line via an extrinsic pathway. In the present study, the effects of SJKJT-induced autophagy and the cytotoxic mechanisms mediating these effects were investigated in HepG2 cells. The cytotoxicity of SJKJT in the HepG2 cells was evaluated using a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay. The results demonstrated that the half-maximal inhibitory concentration of SJKJT was 2.91 mg/ml at 24 h, 1.64 mg/ml at 48 h and 1.26 mg/ml at 72 h. The results of confocal fluorescence microscopy indicated that SJKJT resulted in the accumulation of green fluorescent protein-LC3 and vacuolation of the cytoplasm. Flow cytometric analysis revealed the accumulation of acidic vesicular organelles. Furthermore, western blot analysis, used to determine the expression levels of autophagy-associated proteins, demonstrated that the HepG2 cells treated with SJKJT exhibited LC3B-I/LC3B-II conversion, increased expression levels of Beclin, Atg-3 and Atg-5 and reduced expression levels of p62 and decreased signaling of the phosphoinositide-3 kinase/Akt/mammalian target of rapamycin and the p38 mitogen-activated protein kinase pathways. Taken together, these findings may assist in the development of novel chemotherapeutic agents for the treatment of malignant types of liver cancer.

  13. Sann-Joong-Kuey-Jian-Tang induces autophagy in HepG2 cells via regulation of the phosphoinositide-3 kinase/Akt/mammalian target of rapamycin and p38 mitogen-activated protein kinase pathways

    PubMed Central

    CHUANG, WAN-LING; SU, CHIN-CHENG; LIN, PING-YI; LIN, CHI-CHEN; CHEN, YAO-LI

    2015-01-01

    Sann-Joong-Kuey-Jian-Tang (SJKJT), a traditional Chinese medicine, was previously reported to induce autophagy and inhibit the proliferation of the human HepG2 hepatocellular carcinoma cell line via an extrinsic pathway. In the present study, the effects of SJKJT-induced autophagy and the cytotoxic mechanisms mediating these effects were investigated in HepG2 cells. The cytotoxicity of SJKJT in the HepG2 cells was evaluated using a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay. The results demonstrated that the half-maximal inhibitory concentration of SJKJT was 2.91 mg/ml at 24 h, 1.64 mg/ml at 48 h and 1.26 mg/ml at 72 h. The results of confocal fluorescence microscopy indicated that SJKJT resulted in the accumulation of green fluorescent protein-LC3 and vacuolation of the cytoplasm. Flow cytometric analysis revealed the accumulation of acidic vesicular organelles. Furthermore, western blot analysis, used to determine the expression levels of autophagy-associated proteins, demonstrated that the HepG2 cells treated with SJKJT exhibited LC3B-I/LC3B-II conversion, increased expression levels of Beclin, Atg-3 and Atg-5 and reduced expression levels of p62 and decreased signaling of the phosphoinositide-3 kinase/Akt/mammalian target of rapamycin and the p38 mitogen-activated protein kinase pathways. Taken together, these findings may assist in the development of novel chemotherapeutic agents for the treatment of malignant types of liver cancer. PMID:25847489

  14. Overcoming barriers in trajectory space: mechanism and kinetics of rare events via Wang-Landau enhanced transition path sampling.

    PubMed

    Borrero, Ernesto E; Dellago, Christoph

    2010-10-07

    Within the framework of transition path sampling (TPS), activation energies can be computed as path ensemble averages without a priori information about the reaction mechanism [C. Dellago and P. G. Bolhuis, Mol. Simul. 30, 795 (2004)]. Activation energies computed for different conditions can then be used to determine by numerical integration the rate constant for a system of interest from the rate constant known for a reference system. However, in systems with complex potential energy surfaces, multiple reaction pathways may exist making ergodic sampling of trajectory space difficult. Here, we present a combination of TPS with the Wang-Landau (WL) flat-histogram algorithm for an efficient sampling of the transition path ensemble. This method, denoted by WL-TPS, has the advantage that from one single simulation, activation energies at different temperatures can be determined even for systems with multiple reaction mechanisms. The proposed methodology for rate constant calculations does not require the knowledge of the reaction coordinate and is generally applicable to Arrhenius and non-Arrhenius processes. We illustrate the applicability of this technique by studying a two-dimensional toy system consisting of a triatomic molecule immersed in a fluid of repulsive soft disks. We also provide an expression for the calculation of activation volumes from path averages such that the pressure dependence of the rate constant can be obtained by numerical integration.

  15. Optimized Wang-Landau sampling of lattice polymers: ground state search and folding thermodynamics of HP model proteins.

    PubMed

    Wüst, Thomas; Landau, David P

    2012-08-14

    Coarse-grained (lattice-) models have a long tradition in aiding efforts to decipher the physical or biological complexity of proteins. Despite the simplicity of these models, however, numerical simulations are often computationally very demanding and the quest for efficient algorithms is as old as the models themselves. Expanding on our previous work [T. Wüst and D. P. Landau, Phys. Rev. Lett. 102, 178101 (2009)], we present a complete picture of a Monte Carlo method based on Wang-Landau sampling in combination with efficient trial moves (pull, bond-rebridging, and pivot moves) which is particularly suited to the study of models such as the hydrophobic-polar (HP) lattice model of protein folding. With this generic and fully blind Monte Carlo procedure, all currently known putative ground states for the most difficult benchmark HP sequences could be found. For most sequences we could also determine the entire energy density of states and, together with suitably designed structural observables, explore the thermodynamics and intricate folding behavior in the virtually inaccessible low-temperature regime. We analyze the differences between random and protein-like heteropolymers for sequence lengths up to 500 residues. Our approach is powerful both in terms of robustness and speed, yet flexible and simple enough for the study of many related problems in protein folding.

  16. Optimized Wang-Landau sampling of lattice polymers: Ground state search and folding thermodynamics of HP model proteins

    NASA Astrophysics Data System (ADS)

    Wüst, Thomas; Landau, David P.

    2012-08-01

    Coarse-grained (lattice-) models have a long tradition in aiding efforts to decipher the physical or biological complexity of proteins. Despite the simplicity of these models, however, numerical simulations are often computationally very demanding and the quest for efficient algorithms is as old as the models themselves. Expanding on our previous work [T. Wüst and D. P. Landau, Phys. Rev. Lett. 102, 178101 (2009)], 10.1103/PhysRevLett.102.178101, we present a complete picture of a Monte Carlo method based on Wang-Landau sampling in combination with efficient trial moves (pull, bond-rebridging, and pivot moves) which is particularly suited to the study of models such as the hydrophobic-polar (HP) lattice model of protein folding. With this generic and fully blind Monte Carlo procedure, all currently known putative ground states for the most difficult benchmark HP sequences could be found. For most sequences we could also determine the entire energy density of states and, together with suitably designed structural observables, explore the thermodynamics and intricate folding behavior in the virtually inaccessible low-temperature regime. We analyze the differences between random and protein-like heteropolymers for sequence lengths up to 500 residues. Our approach is powerful both in terms of robustness and speed, yet flexible and simple enough for the study of many related problems in protein folding.

  17. Rescuing High Avidity T Cells for Prostate Cancer Immunotherapy

    DTIC Science & Technology

    2006-04-01

    lymphoid organs. Eur. J. Immunol. 34:3126-34. (Appendix 1). 2. Xincheng Zheng, Jian-Xin Gao, Xing Chang, Yin Wang , Yan Liu, Jin Wen, Jian Jiang...P. Z., CA69091 and CA58033 to Y. L.), and by the Ohio State University Comprehensive Cancer Center. We thank Dr. Yongjun Liu for helpful discussion... Wang , C., Felio, K., Kantarjian, H. M., Champlin, R. E. and Davis, M. M., Evidence that specific T lymphocytes may participate in the elimination of

  18. Rescuing High Avidity T Cells for Prostate Cancer Immunotherapy

    DTIC Science & Technology

    2005-04-01

    Immunol. (Appendix 1). 2. Xincheng Zheng, Jian-Xin Gao, Xing Chang, Yin Wang , Yan Liu, Jin Wen, Jian Jiang, Yang Liu and Pan Zheng. 2004. B7-CD28...the Ohio State University repertoire of T cells specific for antigens overexpressed in solid Comprehensive Cancer Center. We thank Dr. Yongjun Liu for...tumors. J. Immunol. 2002. 169: 4761-4769. helpful discussion and Ms. Lynde Shaw for editorial 15 Molldrem, J. J., Lee, P. P., Wang , C., Felio, K

  19. Public health impact of disease-behavior dynamics. Comment on "Coupled disease-behavior dynamics on complex networks: A review" by Z. Wang et al.

    NASA Astrophysics Data System (ADS)

    Wells, Chad R.; Galvani, Alison P.

    2015-12-01

    In a loop of dynamic feedback, behavior such as the decision to vaccinate, hand washing, or avoidance influences the progression of the epidemic, yet behavior is driven by the individual's and population's perceived risk of infection during an outbreak. In what we believe will become a seminal paper that stimulates future research as well as an informative teaching aid, Wang et. al. comprehensively review methodological advances that have been used to incorporate human behavior into epidemiological models on the effects of coupling disease transmission and behavior on complex social networks [1]. As illustrated by the recent outbreaks of measles and Middle Eastern Respiratory Syndrome (MERS), here we highlight the importance of coupling behavior and disease transmission that Wang et al. address.

  20. An Example of Wang and Yau's Quasilocal Energy for Constant Radial Spacelike 2-Surfaces in a Maximally Rotating Black Hole Spacetime

    NASA Astrophysics Data System (ADS)

    Ray, Shannon; Miller, Warner

    2017-01-01

    We present the first non-trivial illustration of Wang and Yau's quasilocal energy (WYQLE) for a maximally rotating Kerr spacetime. The surfaces for which we compute quasilocal energy (QLE) are axisymmetric closed space like 2-surfaces S with constant radii in Boyer-Lindquist coordinates. There exists a critical radius r* for which these 2-surfaces are isometrically embeddable in R3 . For surfaces with r >=r* , the WYQLE trivially becomes the Brown and York QLE (BYQLE). To fully illustrate Wang and Yau's formulation, we compute the WYQLE for surfaces with r

  1. Identification of chemical constituents in traditional Chinese medicine formula using HPLC coupled with linear ion trap-Orbitrap MS from high doses of medicinal materials to equivalent doses of formula: Study on Xiang-Sha-Liu-Jun-Zi-Jia-Jian granules.

    PubMed

    Wang, Fengyun; Zhang, Qingqing; Lu, Zhiwei; Wang, Qing; Wang, Meiling; Liu, Yuehong; Fu, Shuang; Gao, Xiaoyan; Tang, Xudong

    2016-05-01

    High-resolution mass spectrometry has been a powerful tool for the research of chemical constituents in traditional Chinese medicine (TCM) formulas. However, the chromatographic peaks were difficult to discriminate clearly in data collection or analysis because of the complexity and the greatly different content of the constituents in TCM formula, which increased the difficulty of identification. In this study, a high-performance liquid chromatography coupled with linear ion trap-Orbitrap mass spectrometry based strategy focused on the comprehensive identification of TCM formula constituents was developed. Identification was carried out from a high dose of medicinal materials to equivalent dose of formula. Meanwhile, combined with mass spectrometry data, chromatographic behaviors, reference standards and previous reports, the identification of constituents in Xiang-Sha-Liu-Jun-Zi-Jia-Jian granules was described. 169 compounds were unambiguously or tentatively characterized, mainly including flavonoids, alkaloids, triterpenic acids, triterpene saponins, lactones, sesquiterpenoids and some other compounds. Among them, 11 compounds were unambiguously confirmed by comparing with reference standards. These results demonstrated that the method was effective and reliable for comprehensive identification of constituents of Xiang-Sha-Liu-Jun-Zi-Jia-Jian granules extracts and reveal the material basis of its therapeutic effects. This strategy might propose a research idea for the characterization of multi-constituents in TCM formula.

  2. Characterization and Optimization of Amylase Production in WangLB, a High Amylase-Producing Strain of Bacillus.

    PubMed

    Wang, Shihui; Jeyaseelan, Jenasia; Liu, Yun; Qin, Wensheng

    2016-09-01

    The costs of amylase represent ca. 24 % of the expenditures in the starch industry and an increase in amylase production and/or activity will greatly cut down on production costs. In the present study, we obtained a high amylase-producing strain of bacteria, WangLB, and identified it as a member of the Bacillus genus based on 16S rDNA analysis. The fermentation conditions for amylase production in the strain were optimized, and the maximum amylase activity we obtained was 26,670 ± 1390 U/mL, under the optimized conditions of 48-h incubation in liquid starch medium, 35 °C, pH 10, 1 % v/v inoculum concentration, 20 g/L starch concentration, and 0.1 % w/v peptone. The influences of 16 small organic inducers on amylase production were tested, and the results showed that 20 mmol/L alanine greatly enhanced amylase production to 290 % of the baseline level. We also conducted an amylase enzymology analysis. The molecular weight of the amylase was 55 kD, determined by SDS-PAGE. The optimum temperature and pH for the amylase were 55 °C and pH 9, respectively. The enzyme also showed high activity over a wide range of temperatures (50-85 °C) and pH values (3-10), and the activity of the amylase was Ca(2+) independent. The kinetic parameters K m and V max were 0.37 ± 0.02 mg/mL and 233 U/mg, respectively. Finally, the amylase was applied to the hydrolysis of five different brands of starch. It was found that the hydrolyzability of the substrate by amylase increased along with starch solubility.

  3. Sann-Joong-Kuey-Jian-Tang inhibits hepatocellular carcinoma Hep-G2 cell proliferation by increasing TNF-α, Caspase-8, Caspase- 3 and Bax but by decreasing TCTP and Mcl-1 expression in vitro.

    PubMed

    Chen, Yao-Li; Yan, Meng-Yi; Chien, Su-Yu; Kuo, Shou-Jen; Chen, Dar-Ren; Cheng, Chun-Yuan; Su, Chin-Cheng

    2013-05-01

    Hepatic cancer remains a challenging disease and there is a need to identify new treatments. Sann-Joong-Kuey-Jian-Tang (SJKJT), a traditional medicinal prescription, has been used to treat lymphadenopathy and exhibits cytotoxic activity in many types of human cancer cells. Our previous studies revealed that SJKJT is capable of inhibiting colon cancer colo 205 cells by inducing autophagy and apoptosis. However, the effects and molecular mechanisms of SJKJT in human hepatocellular carcinoma have not been clearly elucidated. In the present study we evaluated the effects of SJKJT in human hepatic cellular carcinoma Hep-G2 cells. The cytotoxicity of SJKJT in Hep-G2 cells was measured by MTT assay. The cell cycles were analyzed by fluorescence‑activated cell sorting (FACS). The protein expression of translationally controlled tumor protein (TCTP), Mcl-1, Fas, TNF-α, Caspase-8, Caspase-3 and Bax in Hep-G2 cells treated with SJKJT was evaluated by western blotting. The protein expression of Caspase-3 was also detected by immunofluorescence staining. The results showed that SJKJT inhibits Hep-G2 cells in a time- and dose‑dependent manner. During SJKJT treatment for 48 and 72 h, the half-maximum inhibitory concentration (IC50) was 1.48 and 0.94 mg/ml, respectively. The FACS results revealed that increased doses of SJKJT were capable of increasing the percentage of cells in the sub-G1 phase. Immunofluorescence staining showed that Hep-G2 treated with SJKJT had increased expression of Caspase-3. The western blot results showed that the protein expression of Fas, TNF-α, Caspase-8, Caspase- 3 and Bax was upregulated, but that of TCTP and Mcl-1 was downregulated in Hep-G2 cells treated with SJKJT. In conclusion, these findings indicated that SJKJT inhibits Hep-G2 cells. One of the molecular mechanisms responsible for this may be the increased Fas, TNF-α, Caspase-8, Caspase- 3 and Bax expression; another mechanism may be via decreasing TCTP and Mcl-1 expression in order

  4. Epigenetic battle of the sexes. Comment on: ;Epigenetic game theory: How to compute the epigenetic control of maternal-to-zygotic transition; by Qian Wang et al.

    NASA Astrophysics Data System (ADS)

    Wu, Song

    2017-03-01

    Qian Wang et al. present an interesting framework, named epigenetic game theory, for modeling sex-based epigenetic dynamics during embryogenesis from a new viewpoint of evolutionary game theory [1]. That is, epigenomes of sperms and oocytes may coordinate through either cooperation or competition, or both, to affect the fitness of embryos. The work uses a set of ordinary differential equations (ODEs) to describe longitudinal trajectories of DNA methylation levels in both parental and maternal gametes and their dependence on each other. The insights gained from this review, i.e. dynamic methylation profiles and their interaction are potentially important to many fields, such as biomedicine and agriculture.

  5. Improved CUDA programs for GPU computing of Swendsen-Wang multi-cluster spin flip algorithm: 2D and 3D Ising, Potts, and XY models

    NASA Astrophysics Data System (ADS)

    Komura, Yukihiro; Okabe, Yutaka

    2016-03-01

    We present new versions of sample CUDA programs for the GPU computing of the Swendsen-Wang multi-cluster spin flip algorithm. In this update, we add the method of GPU-based cluster-labeling algorithm without the use of conventional iteration (Komura, 2015) to those programs. For high-precision calculations, we also add a random-number generator in the cuRAND library. Moreover, we fix several bugs and remove the extra usage of shared memory in the kernel functions.

  6. Examining the phase transition behavior of amphiphilic lipids in solution using statistical temperature molecular dynamics and replica-exchange Wang-Landau methods.

    PubMed

    Gai, Lili; Vogel, Thomas; Maerzke, Katie A; Iacovella, Christopher R; Landau, David P; Cummings, Peter T; McCabe, Clare

    2013-08-07

    Two different techniques - replica-exchange Wang-Landau (REWL) and statistical temperature molecular dynamics (STMD) - were applied to systematically study the phase transition behavior of self-assembling lipids as a function of temperature using an off-lattice lipid model. Both methods allow the direct calculation of the density of states with improved efficiency compared to the original Wang-Landau method. A 3-segment model of amphiphilic lipids solvated in water has been studied with varied particle interaction energies (ε) and lipid concentrations. The phase behavior of the lipid molecules with respect to bilayer formation has been characterized through the calculation of the heat capacity as a function of temperature, in addition to various order parameters and general visual inspection. The simulations conducted by both methods can go to very low temperatures with the whole system exhibiting well-ordered structures. With optimized parameters, several bilayer phases are observed within the temperature range studied, including gel phase bilayers with frozen water, mixed water (i.e., frozen and liquid water), and liquid water, and a more fluid bilayer with liquid water. The results obtained from both methods, STMD and REWL, are consistently in excellent agreement with each other, thereby validating both the methods and the results.

  7. Examining the phase transition behavior of amphiphilic lipids in solution using statistical temperature molecular dynamics and replica-exchange Wang-Landau methods

    NASA Astrophysics Data System (ADS)

    Gai, Lili; Vogel, Thomas; Maerzke, Katie A.; Iacovella, Christopher R.; Landau, David P.; Cummings, Peter T.; McCabe, Clare

    2013-08-01

    Two different techniques - replica-exchange Wang-Landau (REWL) and statistical temperature molecular dynamics (STMD) - were applied to systematically study the phase transition behavior of self-assembling lipids as a function of temperature using an off-lattice lipid model. Both methods allow the direct calculation of the density of states with improved efficiency compared to the original Wang-Landau method. A 3-segment model of amphiphilic lipids solvated in water has been studied with varied particle interaction energies (ɛ) and lipid concentrations. The phase behavior of the lipid molecules with respect to bilayer formation has been characterized through the calculation of the heat capacity as a function of temperature, in addition to various order parameters and general visual inspection. The simulations conducted by both methods can go to very low temperatures with the whole system exhibiting well-ordered structures. With optimized parameters, several bilayer phases are observed within the temperature range studied, including gel phase bilayers with frozen water, mixed water (i.e., frozen and liquid water), and liquid water, and a more fluid bilayer with liquid water. The results obtained from both methods, STMD and REWL, are consistently in excellent agreement with each other, thereby validating both the methods and the results.

  8. Grateloupia tenuis Wang et Luan sp. nov. (Halymeniaceae, Rhodophyta): A New Species from South China Sea Based on Morphological Observation and rbcL Gene Sequences Analysis

    PubMed Central

    Wang, Hongwei; Luan, Rixiao

    2013-01-01

    Grateloupia tenuis Wang et Luan sp. nov. is a new species described from Lingshui, Hainan Province, South China Sea. Based on the external form and internal structure, combined with rbcL gene sequence analysis, Grateloupia tenuis is distinct from other Grateloupia species as follows: (1) thalli is slippery and cartilaginous in texture; possess fewer branches, relatively slight main axes, and two or three dichotomous branches; (2) cortex is 5-6 layers; medulla is solid when young, but hollow in old branches; reproductive structures are dispersed in main axes of thalli and lower portions of branchlets; exhibits Grateloupia-type auxiliary cell ampullae; (3) the four studied G. tenuis sequences were positioned in a large Grateloupia clade of Halymeniaceae, which included sister group generitype G. filicina with 68 bp differences; G. tenuis was determined to be a sister taxon to the G. catenata, G. ramosissima, G. orientalis, and G. filiformis subclade. The pairwise distances between G. tenuis and these species were 39 to 50 bp. The sequences of G. tenuis differed by 81–108 bp from the sequences of other samples in Grateloupia; there are 114–133 bp changes between G. tenuis and other genera of Halymeniaceae. In final analysis, we considered Grateloupia tenuis Wang et Luan sp. nov. to be a new species of genus Grateloupia. PMID:24455703

  9. Grateloupia ramosa Wang & Luan sp. nov. (Halymeniaceae, Rhodophyta), a new species from China based on morphological evidence and comparative rbcL sequences

    NASA Astrophysics Data System (ADS)

    Cao, Cuicui; Liu, Miao; Guo, Shaoru; Zhao, Dan; Luan, Rixiao; Wang, Hongwei

    2016-03-01

    Grateloupia ramosa Wang & Luan sp. nov. (Halymeniaceae, Rhodophyta) is newly described from Hainan Province, southern China. The organism has the following morphological features: (1) purplish red, cartilaginous and lubricous thalli 5-10 cm in height; (2) compressed percurrent axes bearing abundant branches with opposite arrangement; (3) claw-like apices on top, constricted to 2-4 cm at the base; (4) cortex consisting of 3-6 layers of elliptical or anomalous cells and a medulla covered by compact medullary filaments; (5) reproductive structures distributed throughout the thallus, especially centralized at the bottom of the end portion of the branches; and (6) 4-celled Carpogonial branches and 3-celled auxiliary-cell branches, both of the Grateloupia-type. The morphological diff erences were supported by molecular phylogenetics based on ribulose-1, 5-bisphosphate carboxylase/oxygenase ( rbcL) gene sequence analysis. There was only a 1 bp divergence between specimens collected from Wenchang and Lingshui of Hainan province. The new species was embedded in the large Grateloupia clade of the Halymeniaceae. The pairwise distances between G. ramosa and other species within Grateloupia ranged from 26 to 105 bp, within pairwise distances of 13-111 bp between species of the large genus Grateloupia in Halymeniaceae. Thus, we propose this new species as G. ramosa Wang & Luan sp. nov.

  10. Evaluation of the grand-canonical partition function using expanded Wang-Landau simulations. II. Adsorption of atomic and molecular fluids in a porous material.

    PubMed

    Desgranges, Caroline; Delhommelle, Jerome

    2012-05-14

    We propose to apply expanded Wang-Landau simulations to study the adsorption of atomic and molecular fluids in porous materials. This approach relies on a uniform sampling of the number of atoms and molecules adsorbed. The method consists in determining a high-accuracy estimate of the grand-canonical partition function for the adsorbed fluids. Then, using the formalism of statistical mechanics, we calculate absolute and excess thermodynamic properties relevant to adsorption processes. In this paper, we examine the adsorption of argon and carbon dioxide in the isoreticular metal-organic framework (IRMOF-1). We assess the reliability of the method by showing that the predicted adsorption isotherms and isosteric heats are in excellent agreement with simulation results obtained from grand-canonical Monte Carlo simulations. We also show that the proposed method is very efficient since a single expanded Wang-Landau simulation run at a given temperature provides the whole adsorption isotherm. Moreover, this approach provides a direct access to a wide range of thermodynamic properties, such as, e.g., the excess Gibbs free energy and the excess entropy of adsorption.

  11. A new concept: Epigenetic game theory. Comment on: ;Epigenetic game theory: How to compute the epigenetic control of maternal-to-zygotic transition; by Qian Wang et al.

    NASA Astrophysics Data System (ADS)

    Zheng, Xiu-Deng; Tao, Yi

    2017-03-01

    The evolutionary significance of the interaction between paternal and maternal genomes in fertilized zygotes is a very interesting and challenging question. Wang et al. developed the concept of epigenetic game theory, and they try to use this concept to explain the interaction between paternal and maternal genomes in fertilized zygotes [1]. They emphasize that the embryogenesis can be considered as an ecological system in which two highly distinct and specialized gametes coordinate through either cooperation or competition, or both, to maximize the fitness of embryos under Darwinian selection. More specifically, they integrate game theory to model the pattern of coordination of paternal genome and maternal genomes mediated by DNA methylation dynamics, and they called this epigenetic game theory.

  12. Simple deterministic models and applications. Comment on "Coupled disease-behavior dynamics on complex networks: A review" by Z. Wang et al.

    NASA Astrophysics Data System (ADS)

    Yang, Hyun Mo

    2015-12-01

    Currently, discrete modellings are largely accepted due to the access to computers with huge storage capacity and high performance processors and easy implementation of algorithms, allowing to develop and simulate increasingly sophisticated models. Wang et al. [7] present a review of dynamics in complex networks, focusing on the interaction between disease dynamics and human behavioral and social dynamics. By doing an extensive review regarding to the human behavior responding to disease dynamics, the authors briefly describe the complex dynamics found in the literature: well-mixed populations networks, where spatial structure can be neglected, and other networks considering heterogeneity on spatially distributed populations. As controlling mechanisms are implemented, such as social distancing due 'social contagion', quarantine, non-pharmaceutical interventions and vaccination, adaptive behavior can occur in human population, which can be easily taken into account in the dynamics formulated by networked populations.

  13. The structural evolution of hydrogenated silicon carbide nanocrystals: an approach from bond energy model, Wang-Landau method and first-principles studies

    NASA Astrophysics Data System (ADS)

    Wang, Ya-Ting; Zhao, Yu-Jun; Yang, Xiao-Bao

    2016-06-01

    The novel properties of nanomaterials are attributed to their variety of structures, while it is a central task to determine the stable configurations under different environment conditions. Exemplified with the hydrogenated cubic silicon carbide nanocrystals (H-SiCNCs), we propose an efficient approach to determine the stable H-SiCNCs by the convex analysis with the possible candidates pre-screened by the Wang-Landau method and a bond energy model, followed by the property analysis from first-principles. We find that the configurations of H-SiCNCs are dominated by the hydrogen and carbon chemical potentials according to the phase diagram, and there are structural transitions with the increasing size from tetrahedron, hexahedron, to octahedron. The energy gaps of tetrahedral H-SiCNCs are larger than that of octahedral ones at similar sizes, and in hexagonal ones there is a charge separation for the highest occupied molecular orbitals and lowest unoccupied molecular orbitals.

  14. CUDA programs for the GPU computing of the Swendsen-Wang multi-cluster spin flip algorithm: 2D and 3D Ising, Potts, and XY models

    NASA Astrophysics Data System (ADS)

    Komura, Yukihiro; Okabe, Yutaka

    2014-03-01

    We present sample CUDA programs for the GPU computing of the Swendsen-Wang multi-cluster spin flip algorithm. We deal with the classical spin models; the Ising model, the q-state Potts model, and the classical XY model. As for the lattice, both the 2D (square) lattice and the 3D (simple cubic) lattice are treated. We already reported the idea of the GPU implementation for 2D models (Komura and Okabe, 2012). We here explain the details of sample programs, and discuss the performance of the present GPU implementation for the 3D Ising and XY models. We also show the calculated results of the moment ratio for these models, and discuss phase transitions. Catalogue identifier: AERM_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AERM_v1_0.html Program obtainable from: CPC Program Library, Queen’s University, Belfast, N. Ireland Licensing provisions: Standard CPC licence, http://cpc.cs.qub.ac.uk/licence/licence.html No. of lines in distributed program, including test data, etc.: 5632 No. of bytes in distributed program, including test data, etc.: 14688 Distribution format: tar.gz Programming language: C, CUDA. Computer: System with an NVIDIA CUDA enabled GPU. Operating system: System with an NVIDIA CUDA enabled GPU. Classification: 23. External routines: NVIDIA CUDA Toolkit 3.0 or newer Nature of problem: Monte Carlo simulation of classical spin systems. Ising, q-state Potts model, and the classical XY model are treated for both two-dimensional and three-dimensional lattices. Solution method: GPU-based Swendsen-Wang multi-cluster spin flip Monte Carlo method. The CUDA implementation for the cluster-labeling is based on the work by Hawick et al. [1] and that by Kalentev et al. [2]. Restrictions: The system size is limited depending on the memory of a GPU. Running time: For the parameters used in the sample programs, it takes about a minute for each program. Of course, it depends on the system size, the number of Monte Carlo steps, etc. References: [1] K

  15. Wang-Landau density of states based study of the folding-unfolding transition in the mini-protein Trp-cage (TC5b)

    SciTech Connect

    Singh, Priya; Sarkar, Subir K.; Bandyopadhyay, Pradipta

    2014-07-07

    We present the results of a high-statistics equilibrium study of the folding/unfolding transition for the 20-residue mini-protein Trp-cage (TC5b) in water. The ECEPP/3 force field is used and the interaction with water is treated by a solvent-accessible surface area method. A Wang-Landau type simulation is used to calculate the density of states and the conditional probabilities for the various values of the radius of gyration and the number of native contacts at fixed values of energy—along with a systematic check on their convergence. All thermodynamic quantities of interest are calculated from this information. The folding-unfolding transition corresponds to a peak in the temperature dependence of the computed specific heat. This is corroborated further by the structural signatures of folding in the distributions for radius of gyration and the number of native contacts as a function of temperature. The potentials of mean force are also calculated for these variables, both separately and jointly. A local free energy minimum, in addition to the global minimum, is found in a temperature range substantially below the folding temperature. The free energy at this second minimum is approximately 5 k{sub B}T higher than the value at the global minimum.

  16. The impact of an underground cut-off wall on nutrient dynamics in groundwater in the lower Wang River watershed, China.

    PubMed

    Kang, Pingping; Xu, Shiguo

    2017-03-01

    Underground cut-off walls in coastal regions are mainly used to prevent saltwater intrusion, but their impact on nutrient dynamics in groundwater is not clear. In this study, a combined analysis of multiple isotopes ([Formula: see text]) and nitrogen and phosphorus concentrations is used in order to assess the impact of the underground cut-off walls on the nutrient dynamics in groundwater in the lower Wang River watershed, China. Compared with the nitrogen and phosphorus concentrations in groundwater downstream of the underground cut-off walls, high [Formula: see text] and total dissolved nitrogen concentrations and similar concentration levels of [Formula: see text] and total dissolved phosphorus are found in groundwater upstream of the underground cut-off walls. The isotopic data indicated the probable occurrence of denitrification and nitrification processes in groundwater upstream, whereas the fingerprint of these processes was not shown in groundwater downstream. The management of fertilizer application is critical to control nitrogen concentrations in groundwater restricted by the underground cut-off walls.

  17. Game theory in epigenetic reprogramming. Comment on: ;Epigenetic game theory: How to compute the epigenetic control of maternal-to-zygotic transition; by Qian Wang et al.

    NASA Astrophysics Data System (ADS)

    Hsu, Fei-Man; Chen, Pao-Yang

    2017-03-01

    Von Neumann and Morgenstern published the Theory of Games and Economic Behavior in 1944, describing game theory as a model in which intelligent rational decision-makers manage to find their best strategies in conflict, cooperative or other mutualistic relationships to acquire the greatest benefit [1]. This model was subsequently incorporated in ecology to simulate the ;fitness; of a species during natural selection, designated evolutionary game theory (EGT) [2]. Wang et al. proposed ;epiGame;, taking paternal and maternal genomes as ;intelligent; players that compete, cooperate or both during embryogenesis to maximize the fitness of the embryo [3]. They further extended game theory to an individual or single cell environment. During early zygote development, DNA methylation is reprogrammed such that the paternal genome is demethylated before the maternal genome. After the reset, the blastocyst is re-methylated during embryogenesis. At that time, the paternal and maternal genomes have a conflict of interest related to the expression of their own genes. The proposed epiGame models such interactive regulation between the parental genomes to reach a balance for embryo development (equation (2)).

  18. Evaluation of the grand-canonical partition function using expanded Wang-Landau simulations. III. Impact of combining rules on mixtures properties

    SciTech Connect

    Desgranges, Caroline; Delhommelle, Jerome

    2014-03-14

    Combining rules, such as the Lorentz-Berthelot rules, are routinely used to calculate the thermodynamic properties of mixtures using molecular simulations. Here we extend the expanded Wang-Landau simulation approach to determine the impact of the combining rules on the value of the partition function of binary systems, and, in turn, on the phase coexistence and thermodynamics of these mixtures. We study various types of mixtures, ranging from systems of rare gases to biologically and technologically relevant mixtures, such as water-urea and water-carbon dioxide. Comparing the simulation results to the experimental data on mixtures of rare gases allows us to rank the performance of combining rules. We find that the widely used Lorentz-Berthelot rules exhibit the largest deviations from the experimental data, both for the bulk and at coexistence, while the Kong and Waldman-Hagler provide much better alternatives. In particular, in the case of aqueous solutions of urea, we show that the use of the Lorentz-Berthelot rules has a strong impact on the Gibbs free energy of the solute, overshooting the value predicted by the Waldman-Hagler rules by 7%. This result emphasizes the importance of the combining rule for the determination of hydration free energies using molecular simulations.

  19. Critical nonequilibrium relaxation in the Swendsen-Wang algorithm in the Berezinsky-Kosterlitz-Thouless and weak first-order phase transitions

    NASA Astrophysics Data System (ADS)

    Nonomura, Yoshihiko; Tomita, Yusuke

    2015-12-01

    Recently we showed that the critical nonequilibrium relaxation in the Swendsen-Wang algorithm is widely described by the stretched-exponential relaxation of physical quantities in the Ising or Heisenberg models. Here we make a similar analysis in the Berezinsky-Kosterlitz-Thouless phase transition in the two-dimensional (2D) X Y model and in the first-order phase transition in the 2D q =5 Potts model and find that these phase transitions are described by the simple exponential relaxation and power-law relaxation of physical quantities, respectively. We compare the relaxation behaviors of these phase transitions with those of the second-order phase transition in the three- and four-dimensional X Y models and in the 2D q -state Potts models for 2 ≤q ≤4 and show that the species of phase transitions can be clearly characterized by the present analysis. We also compare the size dependence of relaxation behaviors of the first-order phase transition in the 2D q =5 and 6 Potts models and propose a quantitative criterion on "weakness" of the first-order phase transition.

  20. Thermodynamics of phase coexistence and metal-nonmetal transition in mercury: assessment of effective potentials via expanded Wang-Landau simulations.

    PubMed

    Desgranges, Caroline; Delhommelle, Jerome

    2014-03-20

    We present molecular simulation results on the thermodynamics of phase transitions (specifically, the vapor-liquid and metal-nonmetal transitions) in mercury, as predicted by effective potential models. We use a recently developed method, known as Expanded Wang-Landau simulations, to determine the grand-canonical partition function of systems of mercury atoms. Using the statistical mechanics formalism, we are then able to determine all thermodynamic properties of the system, including the Gibbs free energy and entropy. Prior experimental and theoretical work has emphasized the strong interplay between the vapor-liquid coexistence and the metal-nonmetal transition. We therefore start by assessing the accuracy of the effective potentials considered in this work through a comparison to the available experimental data. We then analyze the thermodynamics of the nonmetal liquid-metal liquid transition, characterized by sharp variations in the rate of change of Gibbs free energy and enthalpy as a function of density. We also identify a crossover density (10.5 g/cm(3)) consistent with the results of recent ab initio calculations and with the experiment.

  1. Scaling behavior can be tricky: Comment on "Universal scaling for the dilemma strength in evolutionary games" by Z. Wang et al.

    NASA Astrophysics Data System (ADS)

    Hui, Pak Ming; Xu, Chen

    2015-09-01

    Evolutionary game theory is a powerful tool for studying the emergence of cooperation among competing individuals [1]. Popularly studied games include the prisoner's dilemma [2], snowdrift game [3] and stag hunt game [4]. They have been extensively studied for the extent of cooperative behavior under different dilemma strengths. Generally, the games can be defined by a 2 × 2 matrix and thus four payoff elements, T, R, P, and S, for the possible payoffs to players when they use pure strategies against each other. Detailed definitions of the four payoffs are given in the review by Wang et al. [5]. For simplicity, it is often the case that fewer parameters are invoked, e.g. a single parameter [3] and more generally two parameters [6]. Generally speaking, reducing the number of parameters has the effect of restricting the system to a certain subspace of the unreduced case. In addition, the spatial structures, such as a well-mixed population or a population forming a complex network, that govern the competing relationship and environment of the agents, and the evolutionary rules, that govern how agents update their strategies, are vital in determining how cooperation evolves, as well documented in the references of [5].

  2. GPU-based cluster-labeling algorithm without the use of conventional iteration: Application to the Swendsen-Wang multi-cluster spin flip algorithm

    NASA Astrophysics Data System (ADS)

    Komura, Yukihiro

    2015-09-01

    Cluster-labeling algorithms that use a single GPU can be roughly divided into direct and two-stage approaches. To date, both types use an iterative method to compare the labels of nearest-neighbor sites. In this paper, I present a GPU-based cluster-labeling algorithm that does not use conventional iteration. The proposed method is applicable to both direct algorithms and two-stage approaches. Under the proposed approach, only one comparison with the nearest-neighbor site is needed for a two-dimensional (2D) system, and just two comparisons are needed for three-dimensional (3D) systems. As an application of the new cluster-labeling algorithm, I consider the Swendsen-Wang (SW) multi-cluster spin flip algorithm. The performance of the proposed method is compared with that of other cluster-labeling algorithms for the SW multi-cluster spin flip problem using the 2D and 3D Ising models. As a result, the computation time of the new algorithm is shown to be 40% faster than that of the previous algorithm for the 2D Ising model, and 20% faster than that of the previous algorithm for the 3D Ising model at the critical temperature.

  3. Petrochemistry and mineral chemistry of Late Permian hornblendite and hornblende gabbro from the Wang Nam Khiao area, Nakhon Ratchasima, Thailand: Indication of Palaeo-Tethyan subduction

    NASA Astrophysics Data System (ADS)

    Fanka, Alongkot; Tsunogae, Toshiaki; Daorerk, Veerote; Tsutsumi, Yukiyasu; Takamura, Yusuke; Endo, Takahiro; Sutthirat, Chakkaphan

    2016-11-01

    In the Wang Nam Khiao area, Nakhon Ratchasima, northeastern Thailand, there are various mafic-ultramafic plutons composed of hornblendite, hornblende gabbro and hornblende microgabbro. The rocks are generally dominated by hornblende, plagioclase and clinopyroxene. The mineral chemistry and whole-rock geochemistry of hornblendite, hornblende gabbro and hornblende microgabbro show their similarities, suggesting a close relationship of their magmatic evolution. The flat REE pattern and low HREE concentration indicate fractional crystallization from hydrous magma. The enrichment in LILE (e.g. Ba, K, Sr) and depletion of HFSE (e.g. Nb, Ta, Zr) together with compositions of clinopyroxene and hornblende reflect arc-related subduction. Hornblende-plagioclase geothermometry and Al-in-hornblende geobarometry indicate the PT conditions of crystallization are 5.3-9.8 kbar and 670-1000 °C, 7.6-9.0 kbar and 850-950 °C, and 7.6-8.8 kbar and 750-850 °C for hornblendite, hornblende gabbro and hornblende microgabbro, respectively, at the lower crustal depth (28-31 km). Zircon U-Pb age of hornblende microgabbro dike, that intruded into hornblendite, yields 257 Ma of intrusion age, suggesting the emplacement of the mafic-ultramafic rock in this area is related to Late Permian arc magmatism resulted from subduction of Palaeo-Tethys beneath Indochina Terrane.

  4. Retraction statement: ‘Formin‐like2 regulates Rho/ROCK pathway to promote actin assembly and cell invasion of colorectal cancer’ by Yuanfeng Zeng, Huijun Xie, Yudan Qiao, Jianmei Wang, Xiling Zhu, Guoyang He, Yuling Li, Xiaoli Ren, Feifei Wang, Li Liang and Yanqing Ding

    PubMed Central

    2016-01-01

    The above article in Cancer Science (doi: 10.1111/cas.12768), published online on 26 October 2015 in Wiley Online Library (http://wileyonlinelibrary.com), has been retracted by agreement between the authors, the journal Editor in Chief, Yusuke Nakamura, and Wiley Publishing Asia Pty Ltd. The retraction has been agreed as Panels +C3 and +Y27632 of SW480 Mock shown in Figure 2a appear to have been taken from the same image, Panels + C3 and +Y27632 of HT29 FMNL2 shown in Figure 2a appear to have been taken from the same image, Panels shFMNL2‐1 and shmDial1‐1 in Figure 3a appear to have been taken from the same image, shFMNL2‐2 and shmDial1‐2 in Figure 3a appear to have been taken from the same image, Panels of shFMNL2‐1 + shmDial1‐1 and shFMNL2‐1 + shmDial1‐2 of +LPA appear to have been taken from the same image, gel bands of FLAG in Figure 4e appear to have been have been manipulated by erasing gel bands. Reference ZengY , XieH , QiaoY , WangJ , ZhuX , HeG , LiY , RenX , WangF , LiangL , DingY . Formin‐like2 regulates Rho/ROCK pathway to promote actin assembly and cell invasion of colorectal cancer. Cancer Sci 2015; 106: 1385–93. doi: 10.1111/cas.12768 26258642 PMID:27420476

  5. Retraction statement: 'Formin-like2 regulates Rho/ROCK pathway to promote actin assembly and cell invasion of colorectal cancer' by Yuanfeng Zeng, Huijun Xie, Yudan Qiao, Jianmei Wang, Xiling Zhu, Guoyang He, Yuling Li, Xiaoli Ren, Feifei Wang, Li Liang and Yanqing Ding.

    PubMed

    2016-07-01

    The above article in Cancer Science (doi: 10.1111/cas.12768), published online on 26 October 2015 in Wiley Online Library (http://wileyonlinelibrary.com), has been retracted by agreement between the authors, the journal Editor in Chief, Yusuke Nakamura, and Wiley Publishing Asia Pty Ltd. The retraction has been agreed as Panels +C3 and +Y27632 of SW480 Mock shown in Figure 2a appear to have been taken from the same image, Panels + C3 and +Y27632 of HT29 FMNL2 shown in Figure 2a appear to have been taken from the same image, Panels shFMNL2-1 and shmDial1-1 in Figure 3a appear to have been taken from the same image, shFMNL2-2 and shmDial1-2 in Figure 3a appear to have been taken from the same image, Panels of shFMNL2-1 + shmDial1-1 and shFMNL2-1 + shmDial1-2 of +LPA appear to have been taken from the same image, gel bands of FLAG in Figure 4e appear to have been have been manipulated by erasing gel bands. Reference Zeng Y, Xie H, Qiao Y, Wang J, Zhu X, He G, Li Y, Ren X, Wang F, Liang L, Ding Y. Formin-like2 regulates Rho/ROCK pathway to promote actin assembly and cell invasion of colorectal cancer. Cancer Sci 2015; 106: 1385-93. doi: 10.1111/cas.12768.

  6. Using game theory to investigate the epigenetic control mechanisms of embryo development. Comment on: ;Epigenetic game theory: How to compute the epigenetic control of maternal-to-zygotic transition; by Qian Wang et al.

    NASA Astrophysics Data System (ADS)

    Zhang, Le; Zhang, Shaoxiang

    2017-03-01

    A body of research [1-7] has already shown that epigenetic reprogramming plays a critical role in maintaining the normal development of embryos. However, the mechanistic quantitation of the epigenetic interactions between sperms and oocytes and the related impact on embryo development are still not clear [6,7]. In this study, Wang et al., [8] develop a modeling framework that addresses this question by integrating game theory and the latest discoveries of the epigenetic control of embryo development.

  7. Using game theory to investigate the epigenetic control mechanisms of embryo development: Comment on: "Epigenetic game theory: How to compute the epigenetic control of maternal-to-zygotic transition" by Qian Wang et al.

    PubMed

    Zhang, Le; Zhang, Shaoxiang

    2017-03-01

    A body of research [1-7] has already shown that epigenetic reprogramming plays a critical role in maintaining the normal development of embryos. However, the mechanistic quantitation of the epigenetic interactions between sperms and oocytes and the related impact on embryo development are still not clear [6,7]. In this study, Wang et al., [8] develop a modeling framework that addresses this question by integrating game theory and the latest discoveries of the epigenetic control of embryo development.

  8. A mathematical view for ordinary differential equation models. Comment on ;Epigenetic game theory: How to compute the epigenetic control of maternal-to-zygotic transition; by Qian Wang et al.

    NASA Astrophysics Data System (ADS)

    Fu, Guifang

    2017-03-01

    Qian Wang et al. have written an interesting article to propose a modeling framework named epiGame in this issue of Physics of Life Reviews [1]. The epiGame framework models how the methylation state of paternal and maternal genomes regulates the embryogenesis as an ecological system in which two highly distinct and specialized gametes coordinate through either cooperation or competition, or both, to maximize the fitness of embryos. Qian Wang et al. also provide solid simulation studies and real data analysis to validate the correctness of their epiGame framework. The importance of embryo development and fertility mechanism cannot be overemphasized, hence, I think that the present review by Qian Wang et al. will stand as a useful modeling guide for practicing biologists or researchers in fertility health to quantify how sperms and oocytes interact through epigenetic process to determine embryo development. In addition, it will serve as a source of many important references to work in the reproductive biology field.

  9. Epigenetic information in gametes: Gaming from before fertilization. Comment on ;Epigenetic game theory: How to compute the epigenetic control of maternal-to-zygotic transition; by Qian Wang et al.

    NASA Astrophysics Data System (ADS)

    Shi, Junchao; Zhang, Xudong; Liu, Ying; Chen, Qi

    2017-03-01

    In their interesting article [1] Wang et al. proposed a mathematical model based on evolutionary game theory [2] to tackle the fundamental question in embryo development, that how sperm and egg interact with each other, through epigenetic processes, to form a zygote and direct successful embryo development. This work is based on the premise that epigenetic reprogramming (referring to the erasure and reconstruction of epigenetic marks, such as DNA methylation and histone modifications) after fertilization might be of paramount importance to maintain the normal development of embryos, a premise we fully agree, given the compelling experimental evidence reported [3]. Wang et al. have specifically chosen to employ the well-studied DNA methylation reprogramming process during mammalian early embryo development, as a basis to develop their mathematical model, namely epigenetic game theory (epiGame). They concluded that the DNA methylation pattern in mammalian early embryo could be formulated and quantified, and their model can be further used to quantify the interactions, such as competition and/or cooperation of expressed genes that maximize the fitness of embryos. The efforts by Wang et al. in quantitatively and systematically analyzing the beginning of life apparently hold value and represent a novel direction for future embryo development research from both theoretical and experimental biologists. On the other hand, we see their theory still at its infancy, because there are plenty more parameters to consider and there are spaces for debates, such as the cases of haploid embryo development [4]. Here, we briefly comment on the dynamic process of epigenetic reprogramming that goes beyond DNA methylation, a dynamic interplay that involves histone modifications, non-coding RNAs, transposable elements et al., as well as the potential input of the various types of 'hereditary' epigenetic information in the gametes - a game that has started before the fertilization.

  10. Reciprocity Mechanisms meet together. A previous step to bridge the gap with experiments?. Comment on "Universal scaling for the dilemma strength in evolutionary games", by Z. Wang, et al.

    NASA Astrophysics Data System (ADS)

    Gómez-Gardeñes, Jesús

    2015-09-01

    As it is well-recognized, powerful theoretical schemes for the promotion of cooperation fall into the following five categories: direct reciprocity, indirect reciprocity, kin selection, group selection, and network reciprocity, all of which got a great deal of attention and theoretical validation during the past decades [1,2]. In [3] Wang et al. briefly explain how reciprocity mechanisms work, illustrating the huge amount of theoretical work done in the area during the last decades, to finally pose some of the still unsolved puzzles that need to be solved in order to achieve a full (theoretical) understanding of the mechanisms that allow cooperative traits to survive in different scenarios.

  11. JPRS Report, China.

    DTIC Science & Technology

    2007-11-02

    HK2705124188 Beijing JINGJI YANJIU in Chinese No 4, 20 Apr 88 pp 3-10 [Article by Yang Zhongwei (2799 0112 0251), Zhang Shuguang (1728 2562 0342...Congress of Anhui Province on 28 Febru- ary 1988"] [Text] It is resolved to appoint: Zhao Huaishou [6392 2037 1108] Chen Jian [7115 0256] Wu Changqi...3152] Zhang Xuemin [1728 1331 2404] Wang Jie [3769 2638] Wang Shengjun [3769 0524 0193] Chen Ruiding [7115 3843 7844] Jiang Dexing [1203 1795

  12. Ontology Matching Across Domains

    DTIC Science & Technology

    2010-05-01

    matching include GMO [1], Anchor-Prompt [2], and Similarity Flooding [3]. GMO is an iterative structural matcher, which uses RDF bipartite graphs to...AFRL under contract# FA8750-09-C-0058. References [1] Hu, W., Jian, N., Qu, Y., Wang, Y., “ GMO : a graph matching for ontologies”, in: Proceedings of

  13. Retraction: "Down-regulation of Notch-1 is associated with Akt and FoxM1 in inducing cell growth inhibition and apoptosis in prostate cancer cells" by Wang et al.

    PubMed

    2016-08-01

    The above article, published online on July 23, 2010 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the journal Editor in Chief, Gary S. Stein, and Wiley Periodicals, Inc. The retraction has been agreed following an investigation from Wayne State University involving the first author and the corresponding author that found Figures 1B and 3A to be inappropriately manipulated. REFERENCE Wang Z, Li Y, Ahmad A, Banerjee S, Azmi AS, Kong D, Wojewoda C, Miele L, Sarkar FH. 2011. Down-regulation of Notch-1 is associated with Akt and FoxM1 in inducing cell growth inhibition and apoptosis in prostate cancer cells. J Cell Biochem 112:78-88; doi: 10.1002/jcb.22770.

  14. Retraction: "Activated K-Ras and INK4a/Arf Deficiency Promote Aggressiveness of Pancreatic Cancer by Induction of EMT Consistent With Cancer Stem Cell Phenotype" by Wang et al.

    PubMed

    2016-10-01

    The above article, published online on November 23, 2012 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the journal Editor in Chief, Gary S. Stein, and Wiley Periodicals, Inc. The retraction has been agreed following an investigation from Wayne State University involving the first author and the corresponding author that found Figure 4B and C to be inappropriately manipulated and re-labeled. Literature Cited Wang Z, Ali S, Banerjee S, Bao B, Li Y, Azmi AS, Korc M, Sarkar FH. 2013. Activated K-Ras and INK4a/Arf deficiency promote aggressiveness of pancreatic cancer by induction of EMT consistent with cancer stem cell phenotype. J Cell Physiol 228:556-562; doi: 10.1002/jcp.24162.

  15. Retraction: "Down-regulation of Notch-1 and Jagged-1 inhibits prostate cancer cell growth, migration and invasion, and induces apoptosis via inactivation of Akt, mTOR, and NF-κB signaling pathways" by Wang et al.

    PubMed

    2016-08-01

    The above article, published online on January 5, 2010 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the journal Editor in Chief, Gary S. Stein, and Wiley Periodicals, Inc. The retraction has been agreed following an investigation from Wayne State University involving the first author and the corresponding author that found Figure 5A to be inappropriately manipulated. REFERENCE Wang Z, Li Y, Banerjee S, Kong D, Ahmad A, Nogueira V, Hay N, Sarkar FH. 2010. Down-regulation of Notch-1 and Jagged-1 inhibits prostate cancer cell growth, migration and invasion, and induces apoptosis via inactivation of Akt, mTOR, and NF-κB signaling pathways. J Cell Biochem 109:726-736; doi: 10.1002/jcb.22451.

  16. Reply to Comments to X. Li and Y. M. Wang (2011) Comparisons of geoid models over Alaska computed with different Stokes' kernel modifications, JGS 1(2): 136-142 by L. E. Sjöberg

    NASA Astrophysics Data System (ADS)

    Wang, Y.

    2012-01-01

    The authors thank professor Sjöberg for having interest in our paper. The main goal of the paper is to test kernel modification methods used in geoid computations. Our tests found that Vanicek/Kleusberg's and Featherstone's methods fit the GPS/leveling data the best in the relative sense at various cap sizes. At the same time, we also pointed out that their methods are unstable and the mean values change from dm to meters by just changing the cap size. By contrast, the modification of the Wong and Gore type (including the spectral combination, method of Heck and Grüninger) is stable and insensitive to the truncation degree and cap size. This feature is especially useful when we know the accuracy of the gravity field at different frequency bands. For instance, it is advisable to truncate Stokes' kernel at a degree to which the satellite model is believed to be more accurate than surface data. The method of the Wong and Goretype does this job quite well. In contrast, the low degrees of Stokes' kernel are modified by Molodensky's coefficients tn in Vanicek/Kleusberg's and Featherstone's methods (cf. Eq. (6) in Li and Wang (2011)). It implies that the low degree gravity field of the reference model will be altered by less accurate surface data in the final geoid. This is also the cause of the larger variation in mean values of the geoid.

  17. Comment on "Trends and low frequency variability of extra-tropical cyclone activity in the ensemble of twentieth century reanalysis" by Xiaolan L. Wang, Y. Feng, G. P. Compo, V. R. Swail, F. W. Zwiers, R. J. Allan, and P. D. Sardeshmukh, Climate Dynamics, 2012

    NASA Astrophysics Data System (ADS)

    Krueger, Oliver; Feser, Frauke; Bärring, Lars; Kaas, Eigil; Schmith, Torben; Tuomenvirta, Heikki; von Storch, Hans

    2014-02-01

    The main subject of this article is to comment on the issue of storminess trends derived from the twentieth century reanalysis (20CR) and from observations in the North Atlantic region written about in Wang et al. (Clim Dyn 40(11-12):2775-2800, 2012). The statement that the 20CR estimates would be consistent with storminess derived from pressure-based proxies does not hold for the time prior to 1950.

  18. Epigenetic game theory and its application in plants. Comment on: ;Epigenetic game theory: How to compute the epigenetic control of maternal-to-zygotic transition; by Qian Wang et al.

    NASA Astrophysics Data System (ADS)

    Zhang, Yuan-Ming; Zhang, Yinghao; Guo, Mingyue

    2017-03-01

    Wang's et al. article [1] is the first to integrate game theory (especially evolutionary game theory) with epigenetic modification of zygotic genomes. They described and assessed a modeling framework based on evolutionary game theory to quantify, how sperms and oocytes interact through epigenetic processes, to determine embryo development. They also studied the internal mechanisms for normal embryo development: 1) evolutionary interactions between DNA methylation of the paternal and maternal genomes, and 2) the application of game theory to formulate and quantify how different genes compete or cooperate to regulate embryogenesis through methylation. Although it is not very comprehensive and profound regarding game theory modeling, this article bridges the gap between evolutionary game theory and the epigenetic control of embryo development by powerful ordinary differential equations (ODEs). The epiGame framework includes four aspects: 1) characterizing how epigenetic game theory works by the strategy matrix, in which the pattern and relative magnitude of the methylation effects on embryogenesis, are described by the cooperation and competition mechanisms, 2) quantifying the game that the direction and degree of P-M interactions over embryo development can be explained by the sign and magnitude of interaction parameters in model (2), 3) modeling epigenetic interactions within the morula, especially for two coupled nonlinear ODEs, with explicit functions in model (4), which provide a good fit to the observed data for the two sexes (adjusted R2 = 0.956), and 4) revealing multifactorial interactions in embryogenesis from the coupled ODEs in model (2) to triplet ODEs in model (6). Clearly, this article extends game theory from evolutionary game theory to epigenetic game theory.

  19. New observations - with older ones reviewed - on mass migrations in millipedes based on a recent outbreak on Hachijojima (Izu Islands) of the polydesmid diplopod (Chamberlinius hualienensis, Wang 1956): Nothing appears to make much sense

    PubMed Central

    MEYER-ROCHOW, Victor Benno

    2015-01-01

    Mass aggregations and migrations of millipedes despite numerous attempts to find causes for their occurrences are still an enigma. They have been reported from both southern and northern hemisphere countries, from highlands and lowlands of both tropical and temperate regions and they can involve species belonging to the orders Julida and Spirobolida, Polydesmida and Glomerida. According to the main suggestions put forward in the past, mass occurrences in Diplopoda occur: (1) because of a lack of food and a population increase beyond sustainable levels; (2) for the purpose of reproduction and in order to locate suitable oviposition sites; (3) to find overwintering or aestivation sites; (4) because of habitat disruption and changes in the local environment; (5) as a consequence of weather conditions the year (or winter and spring) before. A recent outbreak (November 2014) of a mass migration of the polydesmid Chamberlinius hualienensis Wang 1956 on the Japanese Izu Island of Hachijojima 300 km to the south of Tokyo gave this author an opportunity to review the existing literature on millipede mass migrations and to carry out additional observations on the phenomenon in the field as well as the laboratory. Hitherto unreported heavy infestations with phoretic deutonymphs of the mite Histiostoma sp. as well as dense populations of internal rhabditid nematodes (Oscheius cf. necromena and an unidentified species of the genus Fictor), suggest that infestations of this kind could be necromenic and either have been a contributing factor for the mass migration or been a consequence of so many individuals occurring together at close proximity. It is concluded that mass migrations and aggregations in millipedes do not have one common cause, but represent phenomena that often are seasonally recurring events and appear identical in their outcome, but which have evolved as responses to different causes in different millipede taxa and therefore need to be examined on a case

  20. Evaluation of the grand-canonical partition function using expanded Wang-Landau simulations. IV. Performance of many-body force fields and tight-binding schemes for the fluid phases of silicon

    NASA Astrophysics Data System (ADS)

    Desgranges, Caroline; Delhommelle, Jerome

    2016-03-01

    We extend Expanded Wang-Landau (EWL) simulations beyond classical systems and develop the EWL method for systems modeled with a tight-binding Hamiltonian. We then apply the method to determine the partition function and thus all thermodynamic properties, including the Gibbs free energy and entropy, of the fluid phases of Si. We compare the results from quantum many-body (QMB) tight binding models, which explicitly calculate the overlap between the atomic orbitals of neighboring atoms, to those obtained with classical many-body (CMB) force fields, which allow to recover the tetrahedral organization in condensed phases of Si through, e.g., a repulsive 3-body term that favors the ideal tetrahedral angle. Along the vapor-liquid coexistence, between 3000 K and 6000 K, the densities for the two coexisting phases are found to vary significantly (by 5 orders of magnitude for the vapor and by up to 25% for the liquid) and to provide a stringent test of the models. Transitions from vapor to liquid are predicted to occur for chemical potentials that are 10%-15% higher for CMB models than for QMB models, and a ranking of the force fields is provided by comparing the predictions for the vapor pressure to the experimental data. QMB models also reveal the formation of a gap in the electronic density of states of the coexisting liquid at high temperatures. Subjecting Si to a nanoscopic confinement has a dramatic effect on the phase diagram with, e.g. at 6000 K, a decrease in liquid densities by about 50% for both CMB and QMB models and an increase in vapor densities between 90% (CMB) and 170% (QMB). The results presented here provide a full picture of the impact of the strategy (CMB or QMB) chosen to model many-body effects on the thermodynamic properties of the fluid phases of Si.

  1. [Contributions of medical practitioners of Xin'an area on acupuncture theory].

    PubMed

    Hu, Ling; Tang, Wei; Wu, Zi-Jian; Liu, Guang-Xia; Niu, Shu-Ping; Bai, Liang-Chuan; Chen, Wei-Hua; Xia, Xiao-Hong; Hu, Wu-Bin

    2012-08-01

    Contributions of Xin'an medical school and physicians to acupuncture theory were introduced in the article. Academic theories or characteristics of several physicians of Xin'an school such as YANG Xuan-cao, WU Kun, WANG Ji, WU Yi-ding, ZHENG Mei-jian and XU Chun-fu, et al were sorted out. Contributions of inheriting and illustrations on acupuncture theory were analyzed so as to expound its significance and value on modern acupucture clinic.

  2. The Second National Chinese Conference on Permafrost, Lanzhou, China, 12-18 October 1981.

    DTIC Science & Technology

    1982-03-01

    in China Lu Guowei et al ., Zonality and regional patterns of frozen 6 ground in northeast China Dai Jinbo and Li Enying, Law of ground temperature...the Qilian Shan area 15 Cheng Guodong and Wang Shaoling, On dividing high altitude 6 permafrost of China into zones Wu Ziwang et al ., Discussion on...Zuofu, Evaluation of permafrost in northeast 21 China since late Pleistocene and its age of formation Sun Jian Zhonz et al ., Paleoenvironment of the

  3. The genus name Ensifer Casida 1982 takes priority over Sinorhizobium Chen et al. 1988, and Sinorhizobium morelense Wang et al. 2002 is a later synonym of Ensifer adhaerens Casida 1982. Is the combination "Sinorhizobium adhaerens" (Casida 1982) Willems et al. 2003 legitimate? Request for an Opinion.

    PubMed

    Young, J M

    2003-11-01

    The synonymy of the genera Ensifer and Sinorhizobium was recently reported, but it was proposed that the later-named genus, Sinorhizobium, take priority in nomenclature. There is no justification in the International Code of Nomenclature of Bacteria (Prokaryotes) for this step; Ensifer is the correct name of the genus, with Ensifer adhaerens as the type species. Species previously allocated to Sinorhizobium are here proposed as the new combinations Ensifer arboris, Ensifer fredii, Ensifer kostiensis, Ensifer kummerowiae, Ensifer medicae, Ensifer meliloti, Ensifer saheli, Ensifer terangae and Ensifer xinjiangensis. Sinorhizobium morelense was proposed in 2002 [Wang, E. T., Tan, Z. Y., Willems, A., Fernández-López, M., Reinhold-Hurek, B. & Martínez-Romero, E., Int J Syst Evol Microbiol 52, 1687-1693, 2002], but a consideration of all published data indicate that it is a nitrogen-fixing genomovar and later heterotypic synonym of Ensifer adhaerens. A Request for an Opinion is made as to whether or not the combination "Sinorhizobium adhaerens" (Casida 1982) Willems et al. 2003 is legitimate.

  4. Retraction RETRACTION of "Methylation of the RASSFIA promoter in breast cancer" by Y. Ji, H.H. Jin, M.D. Wang, W.X. Cao, J.L. Bao - Genet. Mol. Res. 15 (2): gmr.15028261 (2016) - DOI: 10.4238/gmr.15028261.

    PubMed

    Ji, Y; Jin, H H; Wang, M D; Cao, W X; Bao, J L

    2016-10-07

    The retracted article is: Ji Y, Jin HH, Wang MD, Cao WX, et al. (2016). Methylation of the RASSFIA promoter in breast cancer. Genet. Mol. Res. 15: gmr.15028261. There are significant parts of this article (particularly, in the discussion section) that are copied from "Methylation of HIN-1, RASSF1A, RIL and CDH13 in breast cancer is associated with clinical characteristics, but only RASSF1A methylation is associated with outcome", by Jia Xu, Priya B Shetty, Weiwei Feng, Carol Chenault, Robert C Bast Jr, Jean-Pierre J Issa, Susan G Hilsenbeck and Yinhua Yu, published in BMC Cancer 2012; 12: 243. DOI: 10.1186/1471-2407-12-243. The first paragraphs of both discussions are identical. This is concerning. The abstract and introduction sections have much of their text plagiarized. Overall, there is high plagiarism detected. The GMR editorial staff was alerted and after a thorough investigation, we have strong reason to believe that the peer review process was failure and, after review and contacting the authors, the editors of Genetics and Molecular Research decided to retract the article in accordance with the recommendations of the Committee on Publication Ethics (COPE). The authors and their institutions were advised of this serious breach of ethics.

  5. [Contribution of teacher MEI Jian-Han to modern acup-moxibustion science].

    PubMed

    Zhang, Jian-Bin

    2008-09-01

    Acup-moxibustion experts are indispensable for probing into establishment of modern higher education and academic system of acupuncture and moxibustion. Among them, teacher MEI made a great distribution, mainly including: summarizing the outline of indications of acupoints of 14 channels, raising making prescription law of acupoints and indications law of acupoints, expounding the relationship between channels running and disease symptoms, summing up characteristics of theories of the twelve divergent meridians and the twelve muscle regions, drawing an indications diagram of acupoints of the 14 meridians and a schematic diagram of relation between the running of meridians and disease symptoms, a schematic diagram of running of the twelve divergent meridians, and a diagram of the relations between running of the twelve muscle regions and disease symptoms, inventing acupoint location method with finger-equal division, expounding Xiaheshu, simplifying the calculation of Ziwuliuzhu and inventing a calculation scale and simple acupoints selection table. In his later years, he systematically studied on the theories of eight extra meridians and clinical application, and raised theorem of meridians, etc.

  6. Joint Density of States Calculation Employing Wang-Landau Algorithm

    NASA Astrophysics Data System (ADS)

    Kalyan, M. Suman; Bharath, R.; Sastry, V. S. S.; Murthy, K. P. N.

    2016-04-01

    Joint density of states (JDoS), which depends both on energy and another variable like order parameter provides more information than the conventional density of states (DoS) which depend only on energy. Calculation of JDoS requires huge computational time. In this paper we employ two level method to calculate JDoS which requires relatively much less computational time. We demonstrate this method on a two dimensional Ising spin system, lattice spin model of double strand DNA (dsDNA) and Heisenberg ferromagnet.

  7. Distributed calibrating snow models using remotely sensed snow cover information

    NASA Astrophysics Data System (ADS)

    Li, H.

    2015-12-01

    Distributed calibrating snow models using remotely sensed snow cover information Hongyi Li1, Tao Che1, Xin Li1, Jian Wang11. Cold and Arid Regions Environmental and Engineering Research Institute, Chinese Academy of Sciences, Lanzhou 730000, China For improving the simulation accuracy of snow model, remotely sensed snow cover data are used to calibrate spatial parameters of snow model. A physically based snow model is developed and snow parameters including snow surface roughness, new snow density and critical threshold temperature distinguishing snowfall from precipitation, are spatially calibrated in this study. The study region, Babaohe basin, located in northwestern China, have seasonal snow cover and with complex terrain. The results indicates that the spatially calibration of snow model parameters make the simulation results more reasonable, and the simulated snow accumulation days, plot-scale snow depth are more better than lumped calibration.

  8. [Deliberation on the pronunciation and meaning of Miu Ci].

    PubMed

    Zhang, Cui-Hong; Zhang, Chao

    2011-07-01

    As one of the acupuncture approaches mentioned in the Nei Jing, Miu Ci has been widely used in clinical practice, but diverse opinions on Miu's pronunciation and meaning limit its application. Ancient and modern literature has shown that the meanings of 'Miu' include 'difference', 'wrong' and 'cross', and it has mainly two different pronunciations, i.e. 'miü' and 'jiü'. However, 'Miu' always means 'difference' in the Nei Jing, e.g. 'Miu Chu', 'Miu Ci', 'Qi Miu', and in this case, its pronunciation should be 'miü'. Scholars such as YANG Shang-shan, WANG Bing, MA Shi, ZHANG Jie-bin and DANBO YuanJian all held this point of view. We can see that there was no disagreement over Miu's pronunciation and meaning in ancient times. It is a controversy generated in modern times. Therefore, the original written form and pronunciation of 'Miu' should be highly valued.

  9. VizieR Online Data Catalog: Properties of Kepler multi-planet candidate systems (Wang+, 2014)

    NASA Astrophysics Data System (ADS)

    Wang, J.; Xie, J.-W.; Barclay, T.; Fischer, D. A.

    2016-05-01

    Our sample consists of bright host stars with multi-planet transiting systems from Kepler. Out of 5779 Kepler Objects of Interest (http://exoplanetarchive.ipac.caltech.edu/), we selected all the systems with a Kepler magnitude (KP) brighter than 13.5mag and with at least two planet candidates. The sample includes 343 planet candidates (see Table3) in 138 multi-planet candidate systems (see Table2) from the Kepler mission. For these systems, we used archival data from Kepler to characterize their stellar (see Table2) and orbital properties (see Table3). We used UKIRT images to calculate brightness contrast curves and to detect stellar companions around planet candidate host stars (see Table4). (3 data files).

  10. Argonne's Michael Wang talks about the GREET Model for reducing vehicle emi

    SciTech Connect

    Michael Wang

    2012-07-25

    To fully evaluate energy and emission impacts of advanced vehicle technologies and new transportation fuels, the fuel cycle from wells to wheels and the vehicle cycle through material recovery and vehicle disposal need to be considered. Sponsored by the U.S. Department of Energy's Office of Energy Efficiency and Renewable Energy (EERE), Argonne has developed a full life-cycle model called GREET (Greenhouse gases, Regulated Emissions, and Energy use in Transportation). It allows researchers and analysts to evaluate various vehicle and fuel combinations on a full fuel-cycle/vehicle-cycle basis. The first version of GREET was released in 1996. Since then, Argonne has continued to update and expand the model. The most recent GREET versions are the GREET 1 2012 version for fuel-cycle analysis and GREET 2.7 version for vehicle-cycle analysis.

  11. A new approach to Monte Carlo simulations in statistical physics: Wang-Landau sampling

    NASA Astrophysics Data System (ADS)

    Landau, D. P.; Tsai, Shan-Ho; Exler, M.

    2004-10-01

    We describe a Monte Carlo algorithm for doing simulations in classical statistical physics in a different way. Instead of sampling the probability distribution at a fixed temperature, a random walk is performed in energy space to extract an estimate for the density of states. The probability can be computed at any temperature by weighting the density of states by the appropriate Boltzmann factor. Thermodynamic properties can be determined from suitable derivatives of the partition function and, unlike "standard" methods, the free energy and entropy can also be computed directly. To demonstrate the simplicity and power of the algorithm, we apply it to models exhibiting first-order or second-order phase transitions.

  12. VizieR Online Data Catalog: Imperial IRAS-FSC redshift catalogue (IIFSCz) (Wang+, 2009)

    NASA Astrophysics Data System (ADS)

    Wang, L.; Rowan-Robinson, M.

    2010-04-01

    We present a new catalogue, the Imperial IRAS-FSC Redshift Catalogue (IIFSCz), of 60303 galaxies selected at 60um from the IRAS Faint Source Catalogue (FSC). The IIFSCz consists of accurate position, optical, near-infrared and/or radio identifications, spectroscopic redshift (if available) or photometric redshift (if possible), predicted far-infrared (FIR) and submillimetre (submm) fluxes ranging from 12 to 1380um based upon the best-fitting infrared template. About 55% of the galaxies in the IIFSCz have spectroscopic redshifts, and a further 20% have photometric redshifts obtained through either the training set or the template-fitting method. For S(60)>0.36Jy, the 90% completeness limit of the FSC, 90% of the sources have either spectroscopic or photometric redshifts. Scientific applications of the IIFSCz include validation of current and forthcoming infrared and submm/mm surveys such as AKARI, Planck and Herschel, follow-up studies of rare source populations, large-scale structure and galaxy bias, local multiwavelength luminosity functions and source counts. The catalogue is publicly available at http://astro.imperial.ac.uk/~mrr/fss/. (2 data files).

  13. VizieR Online Data Catalog: BP Peg times of maximum light (Wang+, 2014)

    NASA Astrophysics Data System (ADS)

    Wang, S.-M.; Qian, S.-B.; He, J.-J.; Zhou, X.; Zhao, E.-G.

    2015-05-01

    Photometric observations of BP Peg were obtained on November 4, 2013 by using the 1.0-m reflecting telescope at Yunnan Observatories (YNOs) that is equipped with a Cassegrain-focus multicolor CCD photometer. An Andor DW436 2K CCD camera together with the wide-band, Johnson-Cousins Rc and Ic filters, attached to this Cassegrain telescope is used. To increase the photometric precision, we also observed the variable star without filters. BP Peg was also observed on December 29, 2013 by using the 85-cm telescope at the Xinglong Station of National Astronomical Observatory (NAO). The telescope is equipped with a primary-focus multi-color CCD photometer where a PI1024 BFT (Back-illuminated and Frame-Transfer) camera is used as the detector. The wide-band filter in V was used during the observations. (1 data file).

  14. Argonne's Michael Wang talks about the GREET Model for reducing vehicle emi

    ScienceCinema

    Michael Wang

    2016-07-12

    To fully evaluate energy and emission impacts of advanced vehicle technologies and new transportation fuels, the fuel cycle from wells to wheels and the vehicle cycle through material recovery and vehicle disposal need to be considered. Sponsored by the U.S. Department of Energy's Office of Energy Efficiency and Renewable Energy (EERE), Argonne has developed a full life-cycle model called GREET (Greenhouse gases, Regulated Emissions, and Energy use in Transportation). It allows researchers and analysts to evaluate various vehicle and fuel combinations on a full fuel-cycle/vehicle-cycle basis. The first version of GREET was released in 1996. Since then, Argonne has continued to update and expand the model. The most recent GREET versions are the GREET 1 2012 version for fuel-cycle analysis and GREET 2.7 version for vehicle-cycle analysis.

  15. VizieR Online Data Catalog: NGC 2808 AGB and RGB stars Na abundance (Wang+, 2016)

    NASA Astrophysics Data System (ADS)

    Wang, Y.; Primas, F.; Charbonnel, C.; van der Swaelmen, M.; Bono, G.; Chantereau, W.; Zhao, G.

    2016-05-01

    The high-resolution spectra of our sample of AGB and RGB stars in the Galactic globular cluster NGC 2808 were obtained with the high-resolution multi-object spectrograph FLAMES, mounted on ESO/VLT-UT2. A combined mode was used where the brightest five objects was observed with UVES-fibre and the remaining targets with GIRAFFE/Medusa. The basic information of our sample stars are listed in Table 2, including the evolutionary phase, instrument used for observation, coordinates, photometry and barycentric radial velocity. Our Fe abundances were derived from the equivalent widths of Fe lines, while the Na abundances were determined with spectra synthesis. Both FeI and Na abundances have been corrected for the non-LTE effect. In Table 4 we show the derived stellar parameters of our sample stars, and the Na abundances are shown in Table 6. (3 data files).

  16. VizieR Online Data Catalog: Photometric variability search in the CSTAR field (Wang+, 2015)

    NASA Astrophysics Data System (ADS)

    Wang, S.; Zhang, H.; Zhou, X.; Zhou, J.-L.; Fu, J.-N.; Yang, M.; Liu, H.; Xie, J.; Wang, L.; Wang, L.; Wittenmyer, R. A.; Ashley, M. C. B.; Feng, L.-L.; Gong, X.; Lawrence, J. S.; Liu, Q.; Luong-van, D. M.; Ma, J.; Peng, X.; Storey, J. W. V.; Wu, Z.; Yan, J.; Yang, H.; Yang, J.; Yuan, X.; Zhang, T.; Zhang, X.; Zhu, Z.; Zou, H.

    2015-08-01

    Chinese Small Telescope Array (CSTAR), controlled from the PLATO autonomous observatory, consists of four fixed co-aligned 14.5cm (effective aperture of 10cm) telescopes, each with a different optical filter in SDSS bands: r, g, i, and open. CSTAR, the first photometric telescope to enter operation at Dome A, was successfully deployed in 2008 January and operated for the subsequent four winters until it was retrieved in 2012 to be repurposed. The data set analyzed in this work was collected from 2008 March 4 to August 8. In this observing season, about 1728hr observations provided some 0.3million i-band frames for 18145 stars with exposure times of 20s or 30s. A detailed description of the CSTAR observations in 2008 is given in Zhou et al. (2010, J/PASP/122/347). (3 data files).

  17. VizieR Online Data Catalog: Photometry and proper motions in Praesepe (Wang+, 2014)

    NASA Astrophysics Data System (ADS)

    Wang, P. F.; Chen, W. P.; Lin, C. C.; Pandey, A. K.; Huang, C. K.; Panwar, N.; Lee, C. H.; Tsai, M. F.; Tang, C.-H.; Goldman, B.; Burgett, W. S.; Chambers, K. C.; Draper, P. W.; Flewelling, H.; Grav, T.; Heasley, J. N.; Hodapp, K. W.; Huber, M. E.; Jedicke, R.; Kaiser, N.; Kudritzki, R.-P.; Luppino, G. A.; Lupton, R. H.; Magnier, E. A.; Metcalfe, N.; Monet, D. G.; Morgan, J. S.; Onaka, P. M.; Price, P. A.; Stubbs, C. W.; Sweeney, W.; Tonry, J. L.; Wainscoat, R. J.; Waters, C.

    2016-08-01

    Data used in this study include photometry and proper motion measurements within a 5° radius around the Praesepe center (R.A.=08h40m, decl.=+19°42', J2000). Archival data were taken from the 2MASS Point Sources Catalog (2MASS; cat. II/246), PPMXL (Roeser et al. 2010, cat. I/317), and Panoramic Survey Telescope And Rapid Response (Pan-STARRS). Pan-STARRS is a wide-field (7deg2) imaging system, with a 1.8m, f/4.4 telescope, equipped with a 1.4 giga-pixel camera. The prototype (PS1), located atop Haleakala, Maui, USA, has been patrolling the entire sky north of -30° declination since mid-2010 with a combination of gP1, rP1, iP1, zP1, and yP1 bands. The PS1 filters differ slightly from those of the SDSS. The gP1 filter extends 20nm redward of gSDSS for greater sensitivity and lower systematics for photometric redshift estimates. SDSS has no corresponding y filter (Tonry et al. 2012, cat. J/ApJ/750/99). Upon the completion of its 3.5yr mission by early 2014, PS1 will provide reliable photometry and astrometry. Table1 lists the properties of the 1040 candidates. (1 data file).

  18. An Investigation of the Validity of Wang's Formula for the Critical Load for Circular Cylindrical Grids

    NASA Technical Reports Server (NTRS)

    Smull, Leland K.

    1943-01-01

    Four circular cylindrical grids were tested under axial compression to investigate the validity of a theoretical formula for the critical load for such structures. The chief result of the investigation was to throw light on some difficulties connected with the experimental validation of such formulas.

  19. VizieR Online Data Catalog: AQ Boo VRI differential light curves (Wang+, 2016)

    NASA Astrophysics Data System (ADS)

    Wang, S.; Zhang, L.; Pi, Q.; Han, X. L.; Zhang, X.; Lu, H.; Wang, D.; Li, T.

    2016-11-01

    On March 22 and April 19 in 2014, we observed AQ Boo with the 60cm telescope at Xinglong Station of the National Astronomical Observatories of China (NAOC). The CCD camera on this telescope has a resolution of 1024 x 1024 pixels and its corresponding field of view is 17'x17' (Yang, 2013NewA...25..109Y). The other three days of data were obtained using the 1-m telescope at Yunnan Observatory of Chinese Academy of Sciences, on January 20, 21 and February 28 in 2015. The CCD camera on this telescope has a resolution of 2048x2048 pixels and its corresponding field of view is 7.3'x7.3'. Bessel VRI filters were used. The exposure times are 100-170s, 50-100s and 50-80s in the V, R, I bands, respectively. (1 data file).

  20. VizieR Online Data Catalog: Classifications of 188 SNe Ia (Wang+, 2013)

    NASA Astrophysics Data System (ADS)

    Wang, X.; Wang, L.; Filippenko, A. V.; Zhang, T.; Zhao, X.

    2013-04-01

    Type Ia supernovae (SNe Ia) have been used as excellent standardizable candles for measuring cosmic expansion, but their progenitors are still elusive. Here, we report that the spectral diversity of SNe Ia is tied to their birthplace environments. We found that those with high-velocity ejecta are substantially more concentrated in the inner and brighter regions of their host galaxies than are normal-velocity SNe Ia. Furthermore, the former tend to inhabit larger and more luminous hosts. These results suggest that high-velocity SNe Ia likely originate from relatively younger and more metal-rich progenitors than do normal-velocity SNe Ia and are restricted to galaxies with substantial chemical evolution. (1 data file).

  1. JianPi JieDu Recipe Inhibits Epithelial-to-Mesenchymal Transition in Colorectal Cancer through TGF-β/Smad Mediated Snail/E-Cadherin Expression

    PubMed Central

    Liu, Xuan; Deng, Wanli; Chai, Ni; Feng, Yuanyuan; Zhou, Lihong; Sui, Hua; Li, Chunpu; Sun, Xiaoting

    2017-01-01

    JPJD was an ideal alternative traditional Chinese medicine compound in the prevention and treatment of CRC, but its underlying mechanisms has not been fully elucidated. In this study, we demonstrated in vitro that TGF-β-induced EMT promoted the invasion and metastasis of CRC cells, reduced the expression of E-cadherin, and elevated the expression of Vimentin. However, JPJD could inhibit the invasive and migratory ability of TGF-β-stimulated CRC cells in a concentration-dependent manner through increasing the expression of E-cadherin and repressing the expression of Vimentin, as well as the inhibition of TGF-β/Smad signaling pathway. Meanwhile, JPJD reduced the transcriptional activities of EMT-associated factors Snail and E-cadherin during the initiation of TGF-β-induced EMT. In vivo, the results demonstrated that JPJD can significantly inhibit the liver and lung metastasis of orthotopic CRC tumor in nude mice, as well as significantly prolonging the survival time of tumor-bearing in a dose-dependent manner. Additionally, JPJD can upregulate the expression of E-cadherin and Smad2/3 in the cytoplasm and downregulate the expression of Vimentin, p-Smad2/3, and Snail in the orthotopic CRC tumor tissues. In conclusions, our new findings provided evidence that JPJD could inhibit TGF-β-induced EMT in CRC through TGF-β/Smad mediated Snail/E-cadherin expression. PMID:28299321

  2. [Limitations of landscape pattern analysis based on landscape indices: a case study of Lize-jian wetland in Yilan of Taiwan Province, China].

    PubMed

    Lin, Meng-lung; Cao, Yu; Wang, Shin

    2008-01-01

    In this paper, the Lizejian wetland landscape patterns in northeastern Taiwan of China were established by landscape indices and aerial photo interpretation, and a parallel analysis was made on them. The results showed that landscape indices could only indicate the landscape geometric characteristics of the wetland at patch and landscape levels, but could not present its spatial and functional characteristics observed from aerial photos. Combining aerial photo interpretation with landscape indices could be helpful to the holistic understanding of Lizejian wetland' s landscape structure and function, and improve the landscape pattern analysis. The new method for assessing landscape structure from a holistic point of view would play an important role in future landscape ecology research.

  3. Mesoporous Carbons With Self-Assembled High-Activity Surfaces (PREPRINT)

    DTIC Science & Technology

    2006-07-07

    regions, through liquid crystal templating using mesophase pitch or related polyaromatic precursors [13-15 Hurt 2002, Chan 2005, Jian 2003]. Liquid...mesogens in mesophase pitch , which prefer edge-on anchoring onto most (but not all) substrates [13, 26 Hurt 2002, Jian 2003 LC anchoring]. In...and nano-confinement of mesophase pitch in various geometries: (a) cylindrical [15-16 Jian 2003, Jian2006], (b) hour-glass [22 Yang 2003], (c

  4. Orgo Cards: Organic Chemistry Review (Steven Q. Wang, Babak Razani, Edward J. K. Lee, Jennifer Wu, and William Berkowitz)

    NASA Astrophysics Data System (ADS)

    Gooch, Eugene

    2003-09-01

    Most students are intimidated by the reputation of organic chemistry, while others see the course as nonessential to their career goals. While they usually have the ability to meet the challenge and succeed, many seek any mechanism by which they can pass the course with minimal study time. Products like Orgo Cards pander to such desires and will not be of benefit to the student with mediocre talent or poor motivation. The best students who buy this set may be bright enough to focus on those very well done mechanisms. But remember, there’s nothing in Orgo Cards that isn’t already in a good organic text.

  5. Inventing a Modern Lexicon for Grammar in Chinese: The Experience of Wang Fengzao, Ma Jianzhong and Yan Fu

    ERIC Educational Resources Information Center

    Pellin, Tommaso

    2008-01-01

    In China, from the second half of the nineteenth century to the first years of the twentieth century, extensive translation of Western works on science, economics and law was undertaken. The goal was to spread "Western learning", thought of as the key tool for the industrial and military modernization of the country, among the Chinese…

  6. The law of cooperation: Comment on "Universal scaling for the dilemma strength in evolutionary games" by Z. Wang et al.

    NASA Astrophysics Data System (ADS)

    Ichinose, Genki

    2015-09-01

    Cooperation is a behavior that benefits others while incurring costs to the actor. Thus, natural selection favors defection (non-cooperation), which unilaterally takes the benefits without paying any costs, rather than cooperation. Despite this logical consequence, reality is the opposite: Cooperation is ubiquitous at any level from genomes to human societies. This contradiction is known as the puzzle of the evolution of cooperation. For a long time, evolutionary game theorists have used the prisoner's dilemma game (PD) and the chicken game (CH) as the standard models to solve this puzzle. For these researchers, it is recognized that a specific mechanism is needed for the evolution of cooperation [1]. Five mechanisms are proposed: kin selection, direct reciprocity, indirect reciprocity, network reciprocity, and group selection. By using the donor and recipient game (D&R), which is one of the particular forms of PD, Nowak theoretically showed that once benefit (b), cost (c), and the other one or two parameters for each mechanism are given, we (evolutionary game theorists) can immediately know whether cooperation evolves [1]. The point here is that he included those unique parameters for each mechanism into PD and then reformulated the payoff matrix. Therefore, we can use this extended PD as the first scaling parameters.

  7. Equivalence of cooperation indexes. Comment on "Universal scaling for the dilemma strength in evolutionary games" by Z. Wang et al.

    NASA Astrophysics Data System (ADS)

    Martinez-Vaquero, Luis; Grujić, Jelena; Lenaerts, Tom

    2016-03-01

    Symmetric 2 × 2 games where two players can select between two actions and the payoff depends on what they both choose, provide one of the simplest models to study the evolution of cooperation. The actions are usually called cooperation (C) and defection (D) and the payoffs they receive are R (reward for mutual cooperation), P (punishment for mutual defection), T (temptation to defect) and S (suckers payoff). The relative ordering of these 4 payoff values determines the type of dilemma: Prisoner's Dilemma (PD) when T > R > P > S, Snowdrift with T > R > S > P and Stag-Hunt with R > T > P > S. Within the framework of Darwinian Evolution it is well known that in the PD, where both greed (T > R) and fear (P > S) are present, the evolution of cooperation is an important conundrum [1], requiring the identification of mechanisms to overcome it.

  8. Engineering topological states in graphene systems

    NASA Astrophysics Data System (ADS)

    Qiao, Zhenhua

    2013-03-01

    In this talk, I will introduce our recent progress on engineering various topological states in graphene systems. The presentation includes two parts: (i) We show that in monolayer graphene, Rashba spin-orbit coupling (SOC) together with Zeeman field can open a nontrivial bulk gap to host the quantum anomalous-Hall effect. We further show that this can be realized via doping magnetic metal atoms on graphene. In Bernal stacking bilayer graphene, an interlayer potential difference breaks the inversion symmetry and opens a bulk gap to support the quantum valley-Hall effect. We find that Rashba SOC can induce a topological phase transition from the quantum valley-Hall effect to a Z2 topological insulator. When the Zeeman field is further considered, a rich variety of topological phases emerge. (ii) When the mass term (e.g., sublattice potential in monolayer graphene, or interlayer potential difference in bilayer graphene) varies spatially, topologically protected 1D kink states arise along zero lines. We demonstrate that such 1D kink state exhibits zero bend resistance for arbitrary turns in its propagating path. We further point out that similar kink states can be tailored in graphene nanoroads in boron nitride sheets. When the kink current experiences a crossing junction composed of four zero lines, we find the splitting of the 1D kink state at the bifurcation point obeys an explicit law of current partition. Collaborators: Shengyuan A. Yang, Wanxiang Feng, Jun Ding, Jeil Jung, Wang-Kong Tse, Chungwei Lin, Hua Jiang, Haiwen Liu, Junren Shi, Jian Wang, Yugui Yao, Allan H. MacDonald, and Qian Niu

  9. Sann-Joong-Kuey-Jian-Tang decreases the protein expression of mammalian target of rapamycin but increases microtubule associated protein II light chain 3 expression to inhibit human BxPC‑3 pancreatic carcinoma cells.

    PubMed

    Su, Chin-Cheng

    2015-04-01

    Sann‑Joong‑Kuey‑Jian‑Tang (SJKJT), a Traditional Chinese Medicinal prescription, has been used for the treatment of lymphadenopathy and solid tumors, and has shown therapeutic potential in a number of human malignant tumor cell lines, such as Hep‑G2 hepatocellular carcinoma cells. Previous mechanistic studies demonstrated that SJKJT inhibited the proliferation of BxPC‑3 pancreatic carcinoma cells through the extrinsic and intrinsic apoptotic pathways in vitro. SJKJT was also shown to be cytotoxic to colo 205 colon cancer cells by inducing autophagy in vitro. The present study therefore investigated molecular mechanisms of autophagy in human BxPC‑3 pancreatic cancer cells treated with SJKJT. The cytotoxic effects of SJKJT on BxPC‑3 human pancreatic carcinoma cells were evaluated using an MTT assay. Furthermore, the expression of autophagy‑associated proteins, including mammalian target of rapamycin (mTOR), beclin‑1, autophagocytosis‑associated protein (Atg)3, Atg7, Atg5‑Atg12 and microtubule‑associated protein II light chain 3 (LC3‑II), was assessed using western blot analysis. The results demonstrated that BxPC‑3 cells treated with SJKJT exhibited decreased expression levels of mTOR and increased expression of LC3‑II protein. In addition, the expression of the beclin‑1, Atg3, Atg7 and Atg5‑Atg12 proteins was increased during the first 24 h, but decreased from 48 to 72 h. The results showed that SJKJT inhibited the proliferation of human BxPC‑3 pancreatic cancer cells in vitro. A possible underlying molecular mechanism may be the induction of autophagy. Further investigation into the therapeutic potential of SJKJT in human pancreatic cancer is required.

  10. Connecting human behavior and infectious disease spreading. Comment on "Coupled disease-behavior dynamics on complex networks: A review" by Wang et al.

    NASA Astrophysics Data System (ADS)

    Holme, Petter

    2015-12-01

    Vaccination against measles is one of the great success stories of 20th century medicine. In the USA, before the introduction of the vaccine in 1963, three to four million adolescents were infected annually, around 500 died, around 5000 got serious complications (primarily encephalitis, swelling of the brain), and around 50,000 were hospitalized [7]. With the vaccine, measles virtually vanished and by 2000 it was declared extinct from the USA. This was, however, not the end of the story. There is still a small fraction of parents who do not let their children be vaccinated. The reasons vary-fear of side effects, an aversion of exposing children to something ;unnatural;, and a large number of other ideas. (For a non-academic account of the psychology of vaccination, we recommend Eula Biss's On Immunity[3].) The last few decades, anti-vaccination ideas have been spreading in social media and united people opposing vaccination into something of a movement [4]. In December 2014 there was a first larger outbreak (over 500 cases) of the century, centered around Disneyland (Anaheim, California) [10], and the anti-vaccination movement got much of the blame [4]. This example illustrates how ideas and opinions-that just like diseases are spreading over networks of people-can facilitate outbreaks. The reverse is, thankfully, more common-people, aware of an emerging outbreak, try to lower the chance of contagion by improving hygiene etc., which impedes the outbreak.

  11. The importance of accurately modelling human interactions. Comment on "Coupled disease-behavior dynamics on complex networks: A review" by Z. Wang et al.

    NASA Astrophysics Data System (ADS)

    Rosati, Dora P.; Molina, Chai; Earn, David J. D.

    2015-12-01

    Human behaviour and disease dynamics can greatly influence each other. In particular, people often engage in self-protective behaviours that affect epidemic patterns (e.g., vaccination, use of barrier precautions, isolation, etc.). Self-protective measures usually have a mitigating effect on an epidemic [16], but can in principle have negative impacts at the population level [12,15,18]. The structure of underlying social and biological contact networks can significantly influence the specific ways in which population-level effects are manifested. Using a different contact network in a disease dynamics model-keeping all else equal-can yield very different epidemic patterns. For example, it has been shown that when individuals imitate their neighbours' vaccination decisions with some probability, this can lead to herd immunity in some networks [9], yet for other networks it can preserve clusters of susceptible individuals that can drive further outbreaks of infectious disease [12].

  12. International association for the study of lung cancer map, Wang lymph node map and rapid on-site evaluation in transbronchial needle aspiration

    PubMed Central

    Liu, Qing-Hua; Arias, Sixto

    2016-01-01

    The invaluable role of transbronchial needle aspiration (TBNA) in the diagnosis and staging of mediastinal adenopathy and lung cancer has been well established. Different lymph nodes regional nomenclatures and maps had been described over the years. The international association for the study of lung cancer (IASLC) and Wang’s maps complement each other benefiting patients with lung cancer. In this article we briefly reviewed the roles of IALSC, Wang’s maps and ROSE in TBNA. PMID:27747023

  13. Re-parametrizing the dilemmas. Comment on "Universal scaling for the dilemma strength in evolutionary games", by Z. Wang et al.

    NASA Astrophysics Data System (ADS)

    Mobilia, Mauro

    2015-09-01

    Understanding the mechanisms at the origin of cooperation is a major challenge to Darwin's natural selection theory [1]: If only the fittest individuals survive, how to explain the ubiquity of cooperation? Among many examples of altruistic behaviors, one can mention insects that coordinate their efforts for the benefit of their "queen" [2].

  14. Modelling real disease dynamics with behaviourally adaptive complex networks. Comment on "Coupled disease-behavior dynamics on complex networks: A review" by Z. Wang et al.

    NASA Astrophysics Data System (ADS)

    Small, Michael

    2015-12-01

    Mean field compartmental models of disease transmission have been successfully applied to a host of different scenarios, and the Kermack-McKendrick equations are now a staple of mathematical biology text books. In Susceptible-Infected-Removed format these equations provide three coupled first order ordinary differential equations with a very mild nonlinearity and they are very well understood. However, underpinning these equations are two important assumptions: that the population is (a) homogeneous, and (b) well-mixed. These assumptions become closest to being true for diseases infecting a large portion of the population for which inevitable individual effects can be averaged away. Emerging infectious disease (such as, in recent times, SARS, avian influenza, swine flu and ebola) typically does not conform to this scenario. Individual contacts and peculiarities of the transmission network play a vital role in understanding the dynamics of such relatively rare infections - particularly during the early stages of an outbreak.

  15. VizieR Online Data Catalog: MBPT calculations for Ne-like ions (CrXV to KrXXVII) (Wang+, 2016)

    NASA Astrophysics Data System (ADS)

    Wang, K.; Chen, Z. B.; Si, R.; Jonsson, P.; Ekman, J.; Guo, X. L.; Li, S.; Long, F. Y.; Dang, W.; Zhao, X. H.; Hutton, R.; Chen, C. Y.; Yan, J.; Yang, X.

    2016-11-01

    Level energies, wavelengths, electric dipole, magnetic dipole, electric quadrupole, and magnetic quadrupole transition rates, oscillator strengths, and line strengths from combined relativistic configuration interaction and many-body perturbation (MBPT) calculations are reported for the 201 fine-structure states of the 2s22p6, 2s22p53l, 2s2p63l, 2s22p54l, 2s2p64l, 2s22p55l, and 2s22p56l configurations in all Ne-like ions between CrXV and KrXXVII. Calculated level energies and transition data are compared with experiments from the National Institute of Standards and Technology (NIST) and CHIANTI databases, and other recent benchmark calculations. The mean energy difference with the NIST experiments is only 0.05%. The present calculations significantly increase the amount of accurate spectroscopic data for the n>3 states in a number of Ne-like ions of astrophysical interest. A complete data set should be helpful for analyzing new observations from solar and other astrophysical sources, and is also likely to be useful for modeling and diagnosing a variety of plasmas, including astronomical and fusion plasma. (5 data files).

  16. Taxonomic Status, Phylogenetic Affinities and Genetic Diversity of a Presumed Extinct Genus, Paraisometrum W.T. Wang (Gesneriaceae) from the Karst Regions of Southwest China

    PubMed Central

    Chen, Wen-Hong; Shui, Yu-Min; Yang, Jun-Bo; Wang, Hong; Nishii, Kanae; Wen, Fang; Zhang, Zhi-Rong; Möller, Michael

    2014-01-01

    Background The karst regions in South China have an abundance of endemic plants that face high extinction risks. The Chinese Gesneriaceae endemic Paraisometrum mileense ( = Oreocharis mileensis), was presumed extinct for 100 years. After its re-discovery, the species has become one of five key plants selected by the Chinese forestry government to establish a new conservation category for plants with extremely small populations. For conservation purposes, we studied the phylogenetic and population genetic status of P. mileense at the three only known localities in Guangxi, Guizhou and Yunnan. Methodology/Principal Findings We collected 64 samples (52 species) of Oreocharis and 8 samples from three provinces of P. mileense and generated molecular phylogenies, and inferred that P. mileense represents a relatively isolated and derived taxonomic unit within Oreocharis. Phylogeographic results of 104 samples of 12 populations of P. mileense indicated that the populations in Yunnan have derived from those in Guangxi and Guizhou. Based on AFLP data, the populations were found to harbor low levels of genetic diversity (He = 0.118), with no apparent gradient across the species’ range, a restricted gene flow and significant isolation-by-distance with limited genetic differentiation among the populations across the three provinces (FST = 0.207, P<0.001). The 10 populations in Yunnan were found to represent two distinct lineages residing at different altitudes and distances from villages. Conclusion/Significance The low levels of genetic diversity found in P. mileense are perhaps a consequence of severe bottlenecks in the recent past. The distribution of the genetic diversity suggests that all populations are significant for conservation. Current in situ and ex situ measures are discussed. Further conservation actions are apparently needed to fully safeguard this conservation flagship species. Our work provides a model of an integrated study for the numerous endemic species in the karst regions with extremely small populations. PMID:25250568

  17. Dynamically rich, yet parameter-sparse models for spatial epidemiology. Comment on "Coupled disease-behavior dynamics on complex networks: A review" by Z. Wang et al.

    NASA Astrophysics Data System (ADS)

    Jusup, Marko; Iwami, Shingo; Podobnik, Boris; Stanley, H. Eugene

    2015-12-01

    Since the very inception of mathematical modeling in epidemiology, scientists exploited the simplicity ingrained in the assumption of a well-mixed population. For example, perhaps the earliest susceptible-infectious-recovered (SIR) model developed by L. Reed and W.H. Frost in the 1920s [1], included the well-mixed assumption such that any two individuals in the population could meet each other. The problem was that, unlike many other simplifying assumptions used in epidemiological modeling whose validity holds in one situation or the other, well-mixed populations are almost non-existent in reality because the nature of human socio-economic interactions is, for the most part, highly heterogeneous (e.g. [2-6]).

  18. Mathematical universality and direct applicability of evolutionary games. Comment on "Universal scaling for the dilemma strength in evolutionary games", by Z. Wang et al.

    NASA Astrophysics Data System (ADS)

    Arranz, Jordi; Traulsen, Arne

    2015-09-01

    The application of classical game theory to biological sciences allowed researchers to successfully approach problems in theoretical and evolutionary biology in a novel manner [1]. Among those, the evolution of cooperation is the most popular application of evolutionary game theory. The evolution of cooperation is traditionally modeled through games, in particular social dilemmas. These depict situations, in which the interest of an individual is in conflict with the interest of the group, thus games offer an ideal ground to study how cooperation can emerge in the face of natural selection, where individual advantage triumphs over group benefits.

  19. Towards unified characterization of cooperation mechanisms. Comment on "Universal scaling for the dilemma strength in evolutionary games" by Z. Wang et al.

    NASA Astrophysics Data System (ADS)

    Han, The Anh

    2015-09-01

    "I will jump into the river to save two brothers or eight cousins": This famous quote by J.B.S. Haldane accurately anticipates the conditions under which cooperation is the favorable choice in an interaction between genetic relatives. The general condition can later be formulated as a surprisingly simple mathematical expression, known as the Hamilton's rule, stating that natural selection favors cooperation if the genetic relatedness (r) between the donor and the recipient of a cooperative act is greater than its cost (c) to benefit (b) ratio [1]: r > c / b. Motivated by Hamilton's elegant early studies, researchers have attempted to find simple and concise rules that characterize the conditions for cooperation to be selected under various social viscosity [2,3]. For example, the seminal work by M. Nowak [3] in 2006 shows that similarly simple rules can be derived that govern each of the other four popular mechanisms of cooperation-direct reciprocity, indirect reciprocity, group selection and network reciprocity-, which can be expressed via the cost-to-benefit ratio being smaller than some critical value associated with the mechanism at work (as seen, for kin interactions, the critical value is relatedness). However, these rules are restricted to the donor and recipient (D&R) paradigm. The question is thus whether it is possible to obtain simple rules even for the general case? The answer is not trivial as a general two-player game is described by four independent parameters, not just two as in the D&R game.

  20. The impact of information spreading on disease dynamics. Comment on "Coupled disease-behavior on complex networks: A review" by Z. Wang et al.

    NASA Astrophysics Data System (ADS)

    Rodrigues, Francisco A.

    2015-12-01

    Epidemic modeling is fundamental to our understanding of the disease dynamics [1]. Theoretical models have allowed the development of methods for immunization and vaccination policies, being used for disease forecast and control [1-3]. Typically, disease propagation is modeled as a stochastic process in which an infectious agent is transmitted from an infected individual to a susceptible subject via the connection between them [4]. The initial models to describe the disease propagation considered homogeneous-mixing compartmental models [2], which assume that all subjects have identical probabilities of interaction. In this way, the network of contacts is a fully connected graph wherein the interaction might happen between every pair of individuals [2].

  1. Scaling up complexity in host-pathogens interaction models. Comment on "Coupled disease-behavior dynamics on complex networks: A review" by Z. Wang et al.

    NASA Astrophysics Data System (ADS)

    Aguiar, Maíra

    2015-12-01

    Caused by micro-organisms that are pathogenic to the host, infectious diseases have caused debilitation and premature death to large portions of the human population, leading to serious social-economic concerns. The persistence and increase in the occurrence of infectious diseases as well the emergence or resurgence of vector-borne diseases are closely related with demographic factors such as the uncontrolled urbanization and remarkable population growth, political, social and economical changes, deforestation, development of resistance to insecticides and drugs and increased human travel. In recent years, mathematical modeling became an important tool for the understanding of infectious disease epidemiology and dynamics, addressing ideas about the components of host-pathogen interactions. Acting as a possible tool to understand, predict the spread of infectious diseases these models are also used to evaluate the introduction of intervention strategies like vector control and vaccination. Many scientific papers have been published recently on these topics, and most of the models developed try to incorporate factors focusing on several different aspects of the disease (and eventually biological aspects of the vector), which can imply rich dynamic behavior even in the most basic dynamical models. As one example to be cited, there is a minimalistic dengue model that has shown rich dynamic structures, with bifurcations (Hopf, pitchfork, torus and tangent bifurcations) up to chaotic attractors in unexpected parameter regions [1,2], which was able to describe the large fluctuations observed in empirical outbreak data [3,4].

  2. Unifying perspectives on cooperation under social viscosity. Comment on "Universal scaling for the dilemma strength in evolutionary games" by Z. Wang et al.

    NASA Astrophysics Data System (ADS)

    Bauch, Chris T.

    2015-09-01

    How cooperation evolved in populations of self-interested agents puzzled Charles Darwin, who portrayed the paradox in The Descent of Man as such: "He who was ready to sacrifice his life, as many a savage has been, rather than betray his comrades, would often leave no offspring to inherit his noble nature" [1]. Darwin invoked group selection to explain cooperation: if groups of cooperating individuals could work together to outcompete groups of selfish individuals, cooperation could thrive. Fundamentally, this mechanism works by allowing cooperators to interact preferentially with one another: cooperators tend to interact with other co-operators whereas selfish "defectors" tend to interact with other defectors. Since cooperators cooperate and defectors defect, groups of cooperators should do better, on average.

  3. The role of complex networks in behavior epidemiology. Comment on "Coupled disease-behavior dynamics on complex networks: A review" by Z. Wang et al.

    NASA Astrophysics Data System (ADS)

    Zhao, Dawei; Wang, Lianhai

    2015-12-01

    Outbreaks of disease can trigger spontaneous behavioral response of individuals to consider prevention measures (mainly including medical cure and non-pharmaceutical intervention), which usually in turn influence the diffusion of epidemic, namely, forming the interplay between individual behaviors and epidemic dynamics. During the past decade, understanding such coupled disease-behavior dynamics in population has become a critical tool for predicting the disease evolution and designing effective prevention strategies [1-3].

  4. Estimating the dilemma strength for game systems. Comment on "Universal scaling for the dilemma strength in evolutionary games", by Z. Wang et al.

    NASA Astrophysics Data System (ADS)

    Chen, Xiaojie

    2015-09-01

    The puzzle of cooperation exists widely in the realistic world, including biological, social, and engineering systems. How to solve the cooperation puzzle has received considerable attention in recent years [1]. Evolutionary game theory provides a common mathematical framework to study the problem of cooperation. In principle, these practical biological, social, or engineering systems can be described by complex game models composed of multiple autonomous individuals with mutual interactions. And generally there exists a dilemma for the evolution of cooperation in the game systems.

  5. First Radio Burst Imaging Observation From Mingantu Ultrawide Spectral Radioheliograph

    NASA Astrophysics Data System (ADS)

    Yan, Yihua; Chen, Linjie; Yu, Sijie; CSRH Team

    2015-08-01

    Radio imaging spectroscopy over wide range wavelength in dm/cm-bands will open new windows on solar flares and coronal mass ejections by tracing the radio emissions from accelerated electrons. The Chinese Spectral Radioheliograph (CSRH) with two arrays in 400MHz-2GHz /2-15GHz ranges with 64/532 frequency channels have been established in Mingantu Observing Station, Inner Mongolia of China, since 2013 and is in test observations now. CSRH is renamed as MUSER (Mingantu Ultrawide SpEctral Radioheliograph) after it's accomplishment We will introduce the progress and current status of CSRH. Some preliminary results of CSRH will be presented.On 11 Nov2014, the first burst event was registered by MUSER-I array at 400MHz-2GHz waveband. According to SGD event list there was a C-class flare peaked at 04:49UT in the disk center and the radio bursts around 04:22-04:24UT was attributed to this flare. However, MUSER-I image observation of the burst indicates that the radio burst peaked around 04:22UT was due to the eruption at the east limb of the Sun and connected to a CME appeared in that direction about 1 hour later. This demonstrate the importance of the spectroscopy observation of the solar radio burst.Acknowledgement: The CSRH team includes Wei Wang, Zhijun Chen, Fei Liu, Lihong Geng and Jian Zhang and CSRH project is supported by National Major Scientific Equipment R&D Project ZDYZ2009-3. The research was also supported by NSFC grants (11433006, 11221063), MOST grant (MOST2011CB811401), CAS Pilot-B Project (XDB09000000) and Marie Curie PIRSES- GA-295272-RADIOSUN.

  6. Variation in annual runoff of the Jinghe River as influenced by climate change

    NASA Astrophysics Data System (ADS)

    Wang, Y.; Chang, J.

    2014-12-01

    Variation in annual runoff of the Jinghe River as influenced by climate change Jian-xia Chang , Yimin WangInstitute of Water Resources and Hydroelectric Power, Xi'an University of Technology, Xi'an Shaanxi, China The characteristics of hydro-climatic changes in the Jinghe River Basin were analysed based on data collected at hydro-meteorological stations for the period 1960-2010. The analytical results revealed an increasing trend of the air temperature in the last several decades, but decreasing trends for streamflow and precipitation. This paper demonstrates the application of TOPMODEL, a rainfall-runoff model to simulate runoff of the Jinghe River Basin. Global climate model participating in Phase 5 of the Coupled Model Inter-comparison Project (CMIP5) has been used to project climate change of the Jinghe River Basin, by the year 2050. The projected temperature and precipitation were integrated into TOPMODEL to simulate runoff under future climate conditions. The projections show that the Jinghe River Basin tends to become warmer. Annual average maximum and minimum temperature would rise by 4.2℃ and 3.8 ℃ under RCP8.5 in the 2040s. Annual precipitation would also increase by 32 mm-68 mm under both scenarios, notably by 68 mm in 2030s under RCP8.5. The change in spring precipitation is most significant with an increase by 8%-29%. Annual average runoff is likely to increase about by -3%, -1% and 1% in the 2020s, 2030s and the 2040s under RCP 8.5 and by 2%, -8% and 15% under RCP 4.5 relative to the baseline (1990-2010).

  7. PREFACE: Third Conference of the Asian Consortium for Computational Materials Science (ACCMS-3)

    NASA Astrophysics Data System (ADS)

    Wang, Ding-sheng; Chen, Gang

    2006-01-01

    Department of Physics, Tsinghua University. In addition, financial supports from Chinese Academy of Sciences and National Natural Science Foundation of China (NSFC) are gratefully acknowledged. The conference was held at the Institute of Physics, CAS, in its newly built conference hall. The excellent facilities and the competent support of the professional staff, headed by Dr Jian-tao Wang, created a genial environment for scientific discussion and exchange. Their invaluable assistance is also gratefully acknowledged.

  8. THE LITHOSPHERIC MAGNETIC FIELD ALONG THE NISHAN-GUYANG PROFILE, CHINA 6 datesYuan Jiehao1; Gu Zuowen1; Chen Bin1; Xu Rugang2; Wang Lie2; Wang Can1 1. Institute of Geophysics, China Earthquake Administration(IGP CEA), yjh810405@163.com 2. Anhui Earthquake Administration

    NASA Astrophysics Data System (ADS)

    Yuan, J.

    2014-12-01

    In order to research the lithospheric magnetic field and the magnetization structure, the geomagnetic field was surveyed along the Nishan-Guyang profile with 900 km long in the Neimenggu and Shanxi provinces in China. The distance between the adjacent geomagnetic sites is about 7 km along the profile. The geomagnetic data were analyzed, and the lithospheric magnetic field was obtained. Using the upward continuation method, the geomagnetic anomalies in different depths were obtained: the basement anomaly, the upper crust anomaly and the superficial anomaly. Basing on these geomagnetic anomalies, the magnetization structure was obtained by using the software of the ModelVision 11.0. The preliminary results show: (1) The geomagnetic anomalies have good relationship with the local geological structure. (2) The magnetization structure is related to the depth variation of the Curie interface, the values of the magnetic susceptibility, the seismic activity and the tectonic block.

  9. Surface Electrochemistry of Chloro(phthalocyaninato)rhodium(III) species, and Oxygen Reduction Electrocatalysis, Formation of a Dimeric Species

    DTIC Science & Technology

    1991-08-20

    rhodium(III) Species, and Oxygen Reduction Electrocatalysis , Formation of a Dimeric Species By Y.-H. Tse, P. Seymour, N. Kobayashi, H. Lam, C.C. Leznoff... Electrocatalysis , Formation of a Dimeric Species 12. PERSONAL AuTI𔃾OR(S)* Y.-H. Ise, P. Sey;mour, N. Kobayashi, H. Lam, C.C. Leznoff, and A.B.P. L...Oxygen Reduction Electrocatalysis . Formation of a Dimeric Species. Yu-Hong Tse, Penny Seymour, Nagao Kobayashi, 1 Herman Lam, Clifford C. Leznoff. and

  10. Cosmic rays during the unusual solar minimum of 2009

    NASA Astrophysics Data System (ADS)

    Gil, Agnieszka

    Examine the solar activity (SA) parameters during the quite long-lasting minimum epoch 23/24 shows that their values differ substantially in comparison with those measured in previous solar minimum epochs. The Sun was extremely quiet and there were nearly no sunspots (e.g. Smith, 2011). The averaged proton density was lower during this minimum (˜ 0.70) than in the three previous minimum epochs (Jian et al., 2011). The averaged strength of the interplanetary magnetic field during the last minimum was truly low (drop of ˜ 0.36) and the solar wind dynamic pressure decrease (˜ 0.22) was noticed (McComas et al., 2008). Solar polar magnetic fields were weaker (˜ 0.40) during this minimum in comparison with the last three minimum epochs of SA (Wang et al., 2009). Kirk et al. (2009) showed that EUV polar coronal holes area was less (˜ 0.15) than at the beginning of the Solar Cycle no. 23. The solar total irradiance at 1AU was lower more than 0.2Wm (-2) than in the last minimum in 1996 (Fröhlich, 2009). Values of the solar radio flux f10.7 were smaller than for the duration of the recent four minima (Jian et al., 2011). The tilt angle of the heliospheric current sheet declined much slower during the recent minimum in comparison with the previous two. The values of galactic cosmic rays (GCR) intensity measured by neutron monitors were the highest ever recorded (e.g. Moraal and Stoker, 2010). In 2007 neutron monitors achieved values measured during the last negative polarity minimum, 1987, and continued to grow throughout the beginning of 2010. In the same time, the level of anomalous cosmic ray intensities was comparable with the 1987 minimum (Leske et al., 2013). The average amplitude of the 27-days recurrence of the GCR intensity was as high as during the previous minimum epoch 1996 (positive polarity), much higher than during minimum one Hale cycle back (Gil et al., 2012). Modzelewska and Alania (2013) showed that 27-days periodicity of the GCR intensity stable

  11. PREFACE: Cooperative dynamics Cooperative dynamics

    NASA Astrophysics Data System (ADS)

    Gov, Nir

    2011-09-01

    , the biological problems that inspire these physical studies cover fundamental processes, from cell division up to the dynamics within axons and neurons. We would like to acknowledge and thank all contributors for their submissions, which made this special issue possible in the first place. Moreover, we would like to thank the staff at IOP Publishing for helping us with the administrative aspects and for co-ordinating the refereeing process. We hope that readers will enjoy this collection of papers and that it will trigger them to further explore the endless open physics questions presented by biological systems. Cooperative dynamics contents How does the antagonism between capping and anti-capping proteins affect actin network dynamics? Longhua Hu and Garegin A Papoian The emergence of sarcomeric, graded-polarity and spindle-like patterns in bundles of short cytoskeletal polymers and two opposite molecular motorsE M Craig, S Dey and A Mogilner Model of myosin node aggregation into a contractile ring: the effect of local alignmentNikola Ojkic, Jian-Qiu Wu and Dimitrios Vavylonis Loop formation of microtubules during gliding at high densityLynn Liu, Erkan Tüzel and Jennifer L Ross Protein-coat dynamics and cluster phases in intracellular traffickingGreg Huber, Hui Wang and Ranjan Mukhopadhyay Conformational changes, diffusion and collective behavior in monomeric kinesin-based motilityKerwyn Casey Huang, Christian Vega and Ajay Gopinathan One-dimensional deterministic transport in neurons measured by dispersion-relation phase spectroscopyRu Wang, Zhuo Wang, Joe Leigh, Nahil Sobh, Larry Millet, Martha U Gillette, Alex J Levine and Gabriel Popescu

  12. Can you find south using your watch?

    NASA Astrophysics Data System (ADS)

    Jian, Li; Baruch, John

    2011-06-01

    Li Jian and John Baruch examine the astronomical thinking behind the Boy Scout wristwatch compass as a means of direction finding, and assess its usefulness as you move across the surface of the Earth.

  13. In-Situ Scanning Electron Microscopy Comparison of Microstructure and Deformation Between WE43-F and WE43-T5 Magnesium Alloys

    DTIC Science & Technology

    2012-05-01

    In-Situ Scanning Electron Microscopy Comparison of Microstructure and Deformation Between WE43-F and WE43-T5 Magnesium Alloys by Tomoko Sano...Jian Yu, Bruce Davis, Richard DeLorme, and Kyu Cho ARL-RP-367 May 2012 A reprint from Magnesium Technology, pp. 345...Scanning Electron Microscopy Comparison of Microstructure and Deformation Between WE43-F and WE43-T5 Magnesium Alloys Tomoko Sano, Jian Yu, and

  14. Fake "Returnee" Earns 4 Million through Fraudulent Marriages: More than Ten Women Fall for His Claims of Being a Boss and Possessing a House and Car

    ERIC Educational Resources Information Center

    Chinese Education and Society, 2005

    2005-01-01

    This article discusses the case of Wang Ruiliang. Ms. Huang filed a case against Wang Jun, alleging that he had defrauded her. Ms. Huang met a man named Wang Jun in April 2002 through a certain matrimonial agency. Before they had been together for very long, Wang Jun asked to borrow money from Ms. Huang, claiming that he was having difficulties in…

  15. Proceedings of the Annual Rand-China Reform Forum Conference (6th) held in Santa Monica, California on 28-29 August 2003

    DTIC Science & Technology

    2005-01-01

    Hu, Edward Leamer, Renwei Huang, Benjamin Zycher, Yuanlong Wang , K.C. Yeh, Fanzhang Huang, John Despres, Gary Hufbauer, Harold Brown, Jisi Wang ...China’s Banking Industry” by Wang Yuanlong..............................................................53 “China’s Financial Sector: Challenges and...by Dr. Harold Brown...............................137 “New Elements In China-U.S. Strategic Relations” by Wang Jisi........141 ix AGENDA Conference

  16. Applications and extensions of epigenetic game theory. Comment on: ;Epigenetic game theory: How to compute the epigenetic control of maternal-to-zygotic transition; by Qian Wang et al.

    NASA Astrophysics Data System (ADS)

    Wang, Yaqun

    2017-03-01

    The authors are to be congratulated for a thought-provoking article [1], which reviews the epigenetic game theory (epiGame) that utilizes differential equations to study the epigenetic control of embryo development. It is a novel application of evolutionary game theory and provides biology researchers with useful methodologies to address scientific questions related to biological coordination of competition and cooperation.

  17. How to identify the most effective control measures based on disease-behavior coupled mechanisms?. Comment on "Coupled disease-behavior dynamics on complex networks: A review" by Z. Wang et al.

    NASA Astrophysics Data System (ADS)

    Sun, Gui-Quan; Jin, Zhen

    2015-12-01

    Modelling infectious diseases on complex networks is a significant tool to understand the transmission of epidemics in human society, and consequently it has commanded increasing attention in the community of mathematicians, physicists, epidemiologists, public health policy-makers and so on [1-4]. Human behavior responses are associated with the emergence of infectious disease, for instance, wearing masks [5], staying away from a thick crowd [6], cutting contacts with infected individuals [7] and receiving a vaccination [8]. However, infectious diseases and human behavior were often modeled as independent systems in the literature, despite the fact that in the real world they are often mutually influential on each other, and hence their coupling exerts significant impacts on disease spread [9,10].

  18. Integrating evolutionary game theory into epigenetic study of embryonic development. Comment on ;Epigenetic game theory: How to compute the epigenetic control of maternal-to-zygotic transition; by Qian Wang et al.

    NASA Astrophysics Data System (ADS)

    Wang, Zuoheng

    2017-03-01

    DNA methylation is an essential component in the epigenetic regulation of embryonic development, and plays a crucial role in various biological processes, including repression of gene transcription, parent-of-origin genomic imprinting, and X-chromosome inactivation [1-5]. Understanding the epigenetic processes in different stages of embryo development has become an important research topic in the field. It has potential to offer new insight into reproductive medicine and contribute to the improvement of long-term health outcomes.

  19. Is the universal scaling for the dilemma strength still available in populations with heterogeneous connectivity or activities?. Comment on "Universal scaling for the dilemma strength in evolutionary games" by Z. Wang et al.

    NASA Astrophysics Data System (ADS)

    Xia, Cheng-Yi; Wang, Lin

    2015-09-01

    The emergence and maintenance of cooperative behavior are widely observed in various realistic systems, such as cellular organisms, vertebrates, and human society [1]. Understanding the ubiquity of cooperation is a challenging problem, attracting great interest from diverse communities. The development of evolutionary game theory contributes to valuable tools for studying the origin of cooperative behavior and solving related social dilemmas [2]. Five key reciprocal mechanisms to promote the cooperation, including direct reciprocity, indirect reciprocity, network reciprocity, group selection, and kin selection, have been identified [3], inspiring much effort in exploring the effects of game dynamics and population's connectivity structure on the patterns of cooperation. Most of current works generate conclusions by focusing on specific game models or mechanisms, which imply the probable existence of some effective and universal laws.

  20. Dissecting genomic imprinting and genetic conflict from a game theory prospective. Comment on: ;Epigenetic game theory: How to compute the epigenetic control of maternal-to-zygotic transition; by Qian Wang et al.

    NASA Astrophysics Data System (ADS)

    Cui, Yuehua; Yang, Haitao

    2017-03-01

    Epigenetics typically refers to changes in the structure of a chromosome that affect gene activity and expression. Genomic imprinting is a special type of epigenetic phenomenon in which the expression of an allele depends on its parental origin. When an allele inherited from the mother (or father) is imprinted (i.e., silent), it is termed as maternal (or paternal) imprinting. Imprinting is often resulted from DNA methylation and tends to cluster together in the genome [1]. It has been shown to play a key role in many genetic disorders in humans [2]. Imprinting is heritable and undergoes a reprogramming process in gametes before and after fertilization [1]. Sometimes the reprogramming process is not reversible, leading to the loss of imprinting [3]. Although efforts have been made to experimentally or computationally infer imprinting genes, the underlying molecular mechanism that leads to unbalanced allelic expression is still largely unknown.

  1. Evaluation of the grand-canonical partition function using expanded Wang-Landau simulations. V. Impact of an electric field on the thermodynamic properties and ideality contours of water

    NASA Astrophysics Data System (ADS)

    Desgranges, Caroline; Delhommelle, Jerome

    2016-11-01

    Using molecular simulation, we assess the impact of an electric field on the properties of water, modeled with the SPC/E potential, over a wide range of states and conditions. Electric fields of the order of 0.1 V/Å and beyond are found to have a significant impact on the grand-canonical partition function of water, resulting in shifts in the chemical potential at the vapor-liquid coexistence of up to 20%. This, in turn, leads to an increase in the critical temperatures by close to 7% for a field of 0.2 V/Å, to lower vapor pressures, and to much larger entropies of vaporization (by up to 35%). We interpret these results in terms of the greater density change at the transition and of the increased structural order resulting from the applied field. The thermodynamics of compressed liquids and of supercritical water are also analyzed over a wide range of pressures, leading to the determination of the Zeno line and of the curve of ideal enthalpy that span the supercritical region of the phase diagram. Rescaling the phase diagrams obtained for the different field strengths by their respective critical properties allows us to draw a correspondence between these systems for fields of up to 0.2 V/Å.

  2. Photoelectron Spectroscopy Study of [Ta2B6]-: a Hexagonal Bipyramdial Cluster

    NASA Astrophysics Data System (ADS)

    Jian, Tian; Li, Weili; Romanescu, Constantin; Wang, Lai-Sheng

    2014-06-01

    It has been a long-sought goal in cluster science to discover stable atomic clusters as building blocks for cluster-assembled nanomaterials, as exemplified by the fullerenes and their subsequent bulk syntheses.[1,2] Clusters have also been considered as models to understand bulk properties, providing a bridge between molecular and solid-state chemistry.[3] Herein we report a joint photoelectron spectroscopy and theoretical study on the [Ta2B6]- and [Ta2B6] clusters.[4] The photoelectron spectrum of [Ta2B6]- displays a simple spectral pattern and a large HOMO-LUMO gap, suggesting its high symmetry. Theoretical calculations show that both the neutral and anion are D6h pyramidal. The chemical bonding analyses for [Ta2B6] revealed the nature of the B6 and Ta interactions and uncovered strong covalent bonding between B6 and Ta. The D6h-[TaB6Ta] gaseous cluster is reminiscent of the structural pattern in the ReB6X6Re core in the [(Cp*Re)2B6H4Cl2] and the TiB6Ti motif in the newly synthesized Ti7Rh4Ir2B8 solid-state compound.[5,6] The current work provides an intrinsic link between a gaseous cluster and motifs for solid materials. Continued investigations of the transition-metal boron clusters may lead to the discovery of new structural motifs involving pure boron clusters for the design of novel boride materials. Reference [1] H.W. Kroto, J. R. Heath, S. C. OBrien, R. F. Curl, R. E. Smalley, Nature 1985, 318, 162 - 163. [2] W. Krtschmer, L. D. Lamb, K. Fostiropoulos, D. R. Huffman, Nature 1990, 347, 354 - 358. [3] T. P. Fehlner, J.-F. Halet, J.-Y. Saillard, Molecular Clusters: A Bridge to Solid-State Chemitry, Cambridge University Press, UK, 2007. [4] W. L. Li, L. Xie, T. Jian, C. Romanescu, X. Huang, L.-S. Wang, Angew. Chem. Int. Ed. 2014, 126, 1312 - 1316. [5] B. Le Guennic, H. Jiao, S. Kahlal, J.-Y. Saillard, J.-F. Halet, S. Ghosh, M. Shang, A. M. Beatty, A. L. Rheingold, T. P. Fehlner, J. Am. Chem. Soc. 2004, 126, 3203 - 3217. [6] B. P. T. Fokwa, M. Hermus, Angew

  3. A PARMELA model of the CEBAF injector valid over a wide range of beam parameters

    SciTech Connect

    Yuhong Zhang; Kevin Beard; Jay Benesch; Yu-Chiu Chao; Arne Freyberger; Joseph Grames; Reza Kazimi; Geoffrey Krafft; Rui Li; Nikolitsa Merminga; Benard Poelker; Byung Yunn

    2004-07-01

    A PARMELA model of the CEBAF injector valid over a wide range of beam parameters Yuhong Zhang, Kevin Beard, Jay Benesch, Yu-Chiu Chao, Arne Freyberger, Joseph Grames, Reza Kazimi, Geoff Krafft, Rui Li, Lia Merminga, Matt Poelker, Michael Tiefenback, Byung Yunn Thomas Jefferson National Accelerator Facility 12000 Jefferson Avenue, Newport News, VA 23606 USA An earlier PARMELA model of the Jefferson Lab CEBAF photoinjector was recently revised. The initial phase space distribution of an electron bunch was determined by measuring spot size and pulselength of the driver laser and by beam emittance measurements. The improved model has been used for simulations of the simultaneous delivery of the Hall A beam required for a hypernuclear experiment, and the Hall C beam required for the G0 parity violation experiment.

  4. Spent Nuclear Fuel Transport Reliability Study

    SciTech Connect

    Wang, Jy-An John; Wang, Hong; Jiang, Hao

    2016-01-01

    This conference paper was orignated and shorten from the following publisehd PTS documents: 1. Jy-An Wang, Hao Jiang, and Hong Wang, Dynamic Deformation Simulation of Spent Nuclear Fuel Assembly and CIRFT Deformation Sensor Stability Investigation, ORNL/SPR-2015/662, November 2015. 2. Jy-An Wang, Hong Wang, Mechanical Fatigue Testing of High-Burnup Fuel for Transportation Applications, NUREG/CR-7198, ORNL/TM-2014/214, May 2015. 3. Jy-An Wang, Hong Wang, Hao Jiang, Yong Yan, Bruce Bevard, Spent Nuclear Fuel Vibration Integrity Study 16332, WM2016 Conference, March 6 10, 2016, Phoenix, Arizona.

  5. Nuclear Structure in China 2010

    NASA Astrophysics Data System (ADS)

    Bai, Hong-Bo; Meng, Jie; Zhao, En-Guang; Zhou, Shan-Gui

    2011-08-01

    Personal view on nuclear physics research / Jie Meng -- High-spin level structures in [symbol]Zr / X. P. Cao ... [et al.] -- Constraining the symmetry energy from the neutron skin thickness of tin isotopes / Lie-Wen Chen ... [et al.] -- Wobbling rotation in atomic nuclei / Y. S. Chen and Zao-Chun Gao -- The mixing of scalar mesons and the possible nonstrange dibaryons / L. R. Dai ... [et al.] -- Net baryon productions and gluon saturation in the SPS, RHIC and LHC energy regions / Sheng-Qin Feng -- Production of heavy isotopes with collisions between two actinide nuclides / Z. Q. Feng ... [et al.] -- The projected configuration interaction method / Zao-Chun Gao and Yong-Shou Chen -- Applications of Nilsson mean-field plus extended pairing model to rare-earth nuclei / Xin Guan ... [et al.] -- Complex scaling method and the resonant states / Jian-You Guo ... [et al.] -- Probing the equation of state by deep sub-barrier fusion reactions / Hong-Jun Hao and Jun-Long Tian -- Doublet structure study in A[symbol]105 mass region / C. Y. He ... [et al.] -- Rotational bands in transfermium nuclei / X. T. He -- Shape coexistence and shape evolution [symbol]Yb / H. Hua ... [et al.] -- Multistep shell model method in the complex energy plane / R. J. Liotta -- The evolution of protoneutron stars with kaon condensate / Ang Li -- High spin structures in the [symbol]Lu nucleus / Li Cong-Bo ... [et al.] -- Nuclear stopping and equation of state / QingFeng Li and Ying Yuan -- Covariant description of the low-lying states in neutron-deficient Kr isotopes / Z. X. Li ... [et al.] -- Isospin corrections for superallowed [symbol] transitions / HaoZhao Liang ... [et al.] -- The positive-parity band structures in [symbol]Ag / C. Liu ... [et al.] -- New band structures in odd-odd [symbol]I and [symbol]I / Liu GongYe ... [et al.] -- The sd-pair shell model and interacting boson model / Yan-An Luo ... [et al.] -- Cross-section distributions of fragments in the calcium isotopes projectile

  6. PREFACE: XIV International Conference on Calorimetry in High Energy Physics

    NASA Astrophysics Data System (ADS)

    Wang, Yifang

    2011-03-01

    (Texas Tech University), Weidong Li (IHEP) 3) Readout techniques - Gerald Eigen (University of Bergen), Zheng Wang (IHEP) 4) Operating calorimeters and calibration - Marat Gataullin (CERN), Francesco Lanni (BNL) 5) Future calorimetry - Tohru Takeshita (Shinshu University), Lei Xia (Argonne National Laboratory) 6) Astrophysics and neutrino calorimetry - Giuliana Fiorillo (INFN), Hiro Tajima (SLAC) List of Participants AKCHURIN, NuralTexas Tech University AN, ZhenghuaIHEP AUFFRAY, EtiennetteCERN BANFI, DaniloUniversità degli Studi di Milano, INFN BASHARINA-FRESHVILLE, AnastasiaUniversity College London BEAUCHEMIN, Pierre-HuguesUniversity of Oxford BENAGLIA, Andrea DavideUniversity of Milano - Bicocca and INFN BIAN, JianminIHEP BIINO, CristinaINFN BILKI, BurakUniversity of Iowa BLAHA, JanLAPP BOUDRY, VincentLLR / CNRS-IN2P3 CAI, XiaoIHEP CAPONE, AntonioPhysics Department University "La Sapienza" and INFN CAVALLARI, FrancescaCERN and INFN Rome CECCHI, ClaudiaUniversity di Perugia e INFN CHANG, JinfanIHEP CHEN, HuchengBrookhaven National Laboratory CHILDERS, TaylorUniversität Heidelberg - Kirchhoff-Institut für Physik DAO, ValerioGeneva University - DPNC DE LA TAILLE, ChristopheIN2P3/OMEGA-LAL DIEMOZ, MarcellaINFN Roma DOTTI, AndreaCERN EIGEN, GeraldUniversity of Bergen EPIFANOV, DenisBudker Institute of Nuclear Physics FAIVRE, JulienLPSC Grenoble France FANG, JianIHEP FANG, ShuangshiIHEP FANTONI, AlessandraINFN - LNF FERRI, FedericoCEA/Saclay Irfu/SPP FERRONI, FernandoSapienza University & INFN Roma FISK, Henry EugeneFermilab GABALDON, CarolinaCERN GARUTTI, ErikaDESY GAUDIO, GabriellaIstituto Nazionale di Fisica Nucleare - Sezione di Pavia GILLBERG, DagCarleton University GIOVANNINI, PaolaMax-Planck-Institut für Physik GLAZOV, AlexanderDESY GRACHOV, OlegUniversity of Kansas HAPPACHER, FabioINFN HE, MiaoIHEP HORI, YasutoUniversity of Tokyo, CNS HU, TaoIHEP HULTH, Per-OlofStockholm University JUN, Soon YungCarnegie Mellon University JURK, StefanISEG Spezialelektronik gmb

  7. Genetics Home Reference: Schindler disease

    MedlinePlus

    ... or Free article on PubMed Central Desnick RJ, Wang AM. Schindler disease: an inherited neuroaxonal dystrophy due ... Kanzaki T, Yokota M, Irie F, Hirabayashi Y, Wang AM, Desnick RJ. Angiokeratoma corporis diffusum with glycopeptiduria ...

  8. Two new species of the genus Podalonia Fernald from China and a key to the Chinese species of the genus (Hymenoptera: Sphecidae).

    PubMed

    Wang, Chun-Hong; Li, Qiang; Ma, Li

    2016-08-30

    Two new species are described: Podalonia arcuaticlypeata Wang & Ma, sp. nov. from Xinjiang, China and Podalonia bicellularis Wang & Ma, sp. nov. from Qinghai, China. A key to the species of Podalonia from China is provided.

  9. 76 FR 585 - In the Matter of Certain Handbags, Luggage, Accessories and Packaging Thereof; Notice of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-05

    .... Golden West Avenue, Arcadia, CA 91007-6563. Alice Bei Wang (a/k/a Alice B. Wang), 886 S. Golden West..., SW., Suite 401, Washington, DC 20436; and (3) For the investigation so instituted, the Honorable...

  10. China and Proliferation of Weapons of Mass Destruction and Missiles: Policy Issues

    DTIC Science & Technology

    2012-11-07

    Atlanta arrested Wang Xun, a PRC national and U.S. resident. On November 16, the Commerce Department ordered sanctions against Wang . The “Section 721...Xinhua, August 6, 2010; Caixin Wang , August 19, 2010; Washington Post, October 18, 2010; Reuters, October 28, 2010; Tehran Times, April 23, 2011...28 Zhongguo Wang , Beijing, October 31, 2004; Xinhua, Beijing, November 5, 2004; IRNA, Tehran, November 6, 2004; Xinhua, Beijing

  11. Behind the Periscope: Leadership in China’s Navy

    DTIC Science & Technology

    2013-12-01

    estimated) 26 Lt. Gen. Wang Sentai Navy deputy political commissar Late 1960s (estimated)27 Ground forces 2012 VADM Wang Dengping South Sea...General Wang Sentai Most PLA officers of his generation enlisted in their late teens; this suggests that he joined the PLA in the late 1960s. 21...指南) (Beijing: National Defense University Press, 2003), pp. 227-229; Ou Guozheng, Wang Zongyun and Li Gang, eds., A Guide to Practical Political

  12. China Confronts Afghan Drugs: Law Enforcement Views of The Golden Crescent

    DTIC Science & Technology

    2011-03-01

    is Liu Ting and Wang Haijun, “Research on the Illegal Drug Problem Under the Perspective of Non-Traditional Security” (Fei chuantong anquan shiyexia...purported interview with a Ministry of Public Security Counternarcotics Bureau official, Wang Gang. In this interview, Wang asserts that in 2009 alone...related malfeasance of duty crimes. Chengdu Commercial Post (Chengdu shangbao; 成都商报) on Sichuan News Network (Sichuan xinwen wang ; 四川新闻网), June 22, 2010

  13. Moving the Enemy: Operational Art in the Chinese PLA’s Huai Hai Campaign (Leavenworth Paper, Number 22)

    DTIC Science & Technology

    2003-01-01

    Hai Campaign From Beginning to End], QLJ, 24. 68. “Su Yu, Chen Shiju, Zhang Zhen guanyu huaye quanjun da beixian zhudi zhi Tan Zhenlin, Wang Jinan...Zhen guanyu huaye quanjun da beixian zhudi zhi Tan Zhenlin, Wang Jinan, Li Yingxi de dianbao” (Telegram From Su Yu, Chen Shiju, and Zhang Zhen to Tan...quanjun da beixian zhudi zhi Tan Zhenlin, Wang Jinan, Li Yingxi de dianbao” (Telegram From Su Yu, Chen Shiju, and Zhang Zhen to Tan Zhenlin, Wang

  14. InVivo Imaging of Myelination for Drug Discovery and Development in Multiple Sclerosis

    DTIC Science & Technology

    2012-10-01

    highlighted below: 1. Design, synthesis and evaluation of coumarin -based molecular probes for imaging of myelination. (Wang et al, J. Med. Chem...evaluation of coumarin -based molecular probes for imaging of myelination. J Med Chem 54:2331- 2340. Wang C, Popescu DC, Wu C, Zhu J, Macklin W, Wang Y

  15. Comment on “The Molecular Evolutionary Patterns of the Insulin/FOXO Signaling Pathway”

    PubMed Central

    Alvarez-Ponce, David; Aguadé, Montserrat; Rozas, Julio

    2013-01-01

    Letter to the Editor on Wang M, Wang Q, Wang Z, Zhang X, Pan Y. The molecular evolutionary patterns of the insulin/FOXO signaling pathway. Evol Bioinform. 2013;9:1–16. doi: 10.4137/EBO.S10539. PMID:23818748

  16. Validation of Biomarkers of the Tumor Microenvironment

    DTIC Science & Technology

    2014-10-01

    A., Yao , H., Rahmatpanah, F., Xia, X. Q., Xu, Q., Pio, R., Turan, T., Koziol, J. A., Goodison, S., Carpenter, P., Wang-Rodriguez, J., Simoneau, A...Wang, Y., Skarecky, D., Sutton, M., Sawyers, A., Ruckle, H., Carpenter, P. M., Wang-Rodriguez, J., Jiang, J., Deng, M., Pan , C., Zhu, J. G., McLaren, C

  17. Proceedings of the Annual RAND-China Reform Forum Conference (6th) Held in Beijing, China on August 28-29, 2003

    DTIC Science & Technology

    2005-01-01

    Bijian Zheng and Charles Wolf, Jr. William Overholt, Angang Hu, Edward Leamer, Renwei Huang, Benjamin Zycher, Yuanlong Wang , K.C. Yeh, Fanzhang...Huang, John Despres, Gary Hufbauer, Harold Brown, Jisi Wang Approved for public release; distribution unlimited The RAND Corporation is a nonprofit...47 “The Status Quo and Prospect of China’s Banking Industry” by Wang Yuanlong

  18. Battlefield Acoustic Sensing, Multimodal Sensing, and Networked Sensing for Intelligence, Surveillance, and Reconnaissance (ISR) Applications

    DTIC Science & Technology

    2015-09-01

    Intelligence, Surveillance, and Reconnaissance (ISR) Applications by Latasha Solomon, Wesley Wang, and Miriam Häge...Surveillance, and Reconnaissance (ISR) Applications by Latasha Solomon Sensors and Electron Devices Directorate, ARL Wesley Wang...Latasha Solomon, Wesley Wang, and Miriam Hӓge 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S

  19. Quasi-Einstein metrics on hypersurface families

    NASA Astrophysics Data System (ADS)

    Hall, Stuart James

    2013-02-01

    We construct quasi-Einstein metrics on some hypersurface families. The hypersurfaces are circle bundles over the product of Fano, Kähler-Einstein manifolds. The quasi-Einstein metrics are related to various gradient Kähler-Ricci solitons constructed by Dancer and Wang and some Hermitian, non-Kähler, Einstein metrics constructed by Wang and Wang on the same manifolds.

  20. Review of the bamboo-feeding species of tribe Evacanthini (Hemiptera: Cicadellidae) with description of two new species from China.

    PubMed

    Yang, Lin; Chen, Xiang-sheng; Li, Zi-zhong

    2013-01-01

    The bamboo-feeding species of tribe Evacanthini are reviewed. They include 9 genera and 13 species: Angustella leucostriata Li & Wang, 1991, Boundarus nigronotus Zhang, Zhang & Wei, 2010a, Carinata kelloggii (Baker, 1923), C. nigrofasciata Li & Wang, 1994a, Convexana fleura Chen, Yang & Li, 2012, Evacanthus repexus Distant, 1908, Onukia guttata Li & Wang, 1991, O. nigra Li & Wang, 1991, Parapythatnus suiyangensis Li & Li, 2011, Taperus fasciatus Li & Wang, 1994b, T. luchunensis Zhang, Zhang & Wei, 2010b and the two new species, Bundera bambusana sp. nov. and Paraonukia wangnioensis sp. nov. The new species are described and all the species are photographed and illustrated. A key to these 13 species is also given.

  1. PEOPLE’S LIBERATION ARMY AFTER NEXT

    DTIC Science & Technology

    2000-08-01

    Qianxian, April 13, 1999; Chen Hui, “PRC Armed Forces Carry Out Three Major Reforms,” Xinhua, June 14, 1999, FBIS OW1606021799. 5. Wang Ke, note 2. 6...Wang Ke; Jiefangjun Bao, March 22, 1998. 7. Chen Hui, note 6. 74 8. Wang Ke. 9. Jiang Jiesheng, “Change effected in strategic logistics support...Hawaii Inc., 1998, p. 26. 10. Wang Ke. 11. Chen Hui; Rocket Force News, April 2, 1999. 12. Wang Ke. 13. Pei Fang. 14. Chen Hui. 15. Chen Hui. 16. Pei

  2. Quantitative comparisons of analogue models of brittle wedge dynamics

    NASA Astrophysics Data System (ADS)

    Schreurs, Guido

    2010-05-01

    , models accommodated initial shortening by a forward- and a backward-verging thrust. Further shortening was taken up by in-sequence formation of forward-verging thrusts. In all experiments, boundary stresses created significant drag of structures along the sidewalls. We therefore compared the surface slope and the location, dip angle and spacing of thrusts in sections through the central part of the model. All models show very similar cross-sectional evolutions demonstrating reproducibility of first-order experimental observations. Nevertheless, there are significant along-strike variations of structures in map view highlighting the limits of interpretations of analogue model results. These variations may be related to the human factor, differences in model width and/or differences in laboratory temperature and especially humidity affecting the mechanical properties of the granular materials. GeoMod2008 Analogue Team: Susanne Buiter, Caroline Burberry, Jean-Paul Callot, Cristian Cavozzi, Mariano Cerca, Ernesto Cristallini, Alexander Cruden, Jian-Hong Chen, Leonardo Cruz, Jean-Marc Daniel, Victor H. Garcia, Caroline Gomes, Céline Grall, Cecilia Guzmán, Triyani Nur Hidayah, George Hilley, Chia-Yu Lu, Matthias Klinkmüller, Hemin Koyi, Jenny Macauley, Bertrand Maillot, Catherine Meriaux, Faramarz Nilfouroushan, Chang-Chih Pan, Daniel Pillot, Rodrigo Portillo, Matthias Rosenau, Wouter P. Schellart, Roy Schlische, Andy Take, Bruno Vendeville, Matteo Vettori, M. Vergnaud, Shih-Hsien Wang, Martha Withjack, Daniel Yagupsky, Yasuhiro Yamada

  3. Multifractal analysis of 2D gray soil images

    NASA Astrophysics Data System (ADS)

    González-Torres, Ivan; Losada, Juan Carlos; Heck, Richard; Tarquis, Ana M.

    2015-04-01

    Soil structure, understood as the spatial arrangement of soil pores, is one of the key factors in soil modelling processes. Geometric properties of individual and interpretation of the morphological parameters of pores can be estimated from thin sections or 3D Computed Tomography images (Tarquis et al., 2003), but there is no satisfactory method to binarized these images and quantify the complexity of their spatial arrangement (Tarquis et al., 2008, Tarquis et al., 2009; Baveye et al., 2010). The objective of this work was to apply a multifractal technique, their singularities (α) and f(α) spectra, to quantify it without applying any threshold (Gónzalez-Torres, 2014). Intact soil samples were collected from four horizons of an Argisol, formed on the Tertiary Barreiras group of formations in Pernambuco state, Brazil (Itapirema Experimental Station). The natural vegetation of the region is tropical, coastal rainforest. From each horizon, showing different porosities and spatial arrangements, three adjacent samples were taken having a set of twelve samples. The intact soil samples were imaged using an EVS (now GE Medical. London, Canada) MS-8 MicroCT scanner with 45 μm pixel-1 resolution (256x256 pixels). Though some samples required paring to fit the 64 mm diameter imaging tubes, field orientation was maintained. References Baveye, P.C., M. Laba, W. Otten, L. Bouckaert, P. Dello, R.R. Goswami, D. Grinev, A. Houston, Yaoping Hu, Jianli Liu, S. Mooney, R. Pajor, S. Sleutel, A. Tarquis, Wei Wang, Qiao Wei, Mehmet Sezgin. Observer-dependent variability of the thresholding step in the quantitative analysis of soil images and X-ray microtomography data. Geoderma, 157, 51-63, 2010. González-Torres, Iván. Theory and application of multifractal analysis methods in images for the study of soil structure. Master thesis, UPM, 2014. Tarquis, A.M., R.J. Heck, J.B. Grau; J. Fabregat, M.E. Sanchez and J.M. Antón. Influence of Thresholding in Mass and Entropy Dimension of 3-D

  4. Polyhedral Oligomeric Silsesquioxane-Functionalized Perfluorocyclobutyl Aryl Ether Polymers: An Overview of the Synthesis and Properties of Polyhedral Oligomeric Silsesquioxanes (POSS) Functionalized with Perfluorocyclobutyl (PFCB) Aryl Ether Polymer Blends and Copolymers (Preprint)

    DTIC Science & Technology

    2007-10-17

    Contact Analyzer System or a Rime-Hart 100-00 115 Goniometry. Liquid drops were either automatically or manually dispensed with 8 10 L drop sizes...C.; Barthlott, W. Ann. Bot. 1997, 79, 677. 2. Barthlott, W.; Nenhuis, C. Planta 1997, 202, 1. 3. Sun, T.; Feng, L.; Gao, X.; Jian, L. Acc

  5. Gamete and embryo-fetal origins of adult diseases.

    PubMed

    Monti, Manuela

    2016-08-10

    By putting together the most advanced evidences supporting the 'gamete and embryo-fetal origins of adult diseases' the two editors, Prof. He-Feng Huang and Prof. Jian-Zhong Sheng (Hangzhou, People's Republic of China) did a great workk.....

  6. 75 FR 17743 - Ocean Transportation Intermediary License Applicants

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-07

    ...-Vessel-Operating Common Carrier--Ocean Transportation Intermediary: HPK Logistics (USA) Inc., 727 Brea... Individual) Jian Sun, President. Cargo Logistics International, LLC, 8761 Dorchester Road, Suite 205, North.../ CFO/Director (Qualifying Individual). Elite Logistics Corp., 2100 East 223rd Street, Carson, CA...

  7. Preparation Matters

    ERIC Educational Resources Information Center

    Dougherty, Chrys; Mellor, Lynn

    2009-01-01

    In "Orange Juice or Orange Drink?," the authors provided evidence that many students are receiving credit for courses with little indication that they have learned the content implied by the course titles (Dougherty, Mellor, & Jian, 2006). Yet in pursuit of the goal of preparing all students for college and careers, many policymakers…

  8. PREFACE: International Conference on Inverse Problems 2010

    NASA Astrophysics Data System (ADS)

    Hon, Yiu-Chung; Ling, Leevan

    2011-03-01

    Sciences, South KoreaYu Jiang, Hokkaido University, JapanDe-Xing Kong, Zhejiang University, ChinaOlga Krivorotko, Novosibirsk State University, RussiaPhilipp Küegler, Austrian Academy of Sciences, AustriaKiwoon Kwon, Dongguk University, South KoreaChun-Kong Law, National Sun Yat-sen University, TaiwanJune-Yub Lee, Ewha Womans University, South KoreaMing Li, City University of Hong Kong, HKSARMikyoung Lim, Korea Advanced Institute of Science and Technology (KAIST), South KoreaJijun Liu, Southeast University, ChinaXiaodong Liu, Chinese Academy of Sciences, ChinaFuming Ma, Jilin University, ChinaHang Ma, Shanghai University, ChinaValdemar Melicher, Ghent University, BelgiumGen Nakamura, Hokkaido University, JapanLong Tuan Nguyen, Ruhr-Universitat Bochum, GermanyEtibar Panakhov, Firat University, TurkeyRobert Plato, University of Siegen, GermanyJean-Pierre Puel, The University of Tokyo, JapanHans-Jürgen Reinhardt, University of Siegen, GermanyMaxim Shishlenin, Sobolev Institute of Mathematics, RussiaIlya Silvestrov, Institute of Petroleum Geology and Geophysics SB RAS, RussiaMourad Sini, Austrian Academy of Sciences, AustriaJán Sládek, Slovak Academy of Sciences, SlovakiaZhijun Tan, Sun Yat-sen University, ChinaQuan-Fang Wang, The Chinese University of Hong Kong, HKSARWenyan Wang, The University of Tokyo, JapanPihua Wen, Queen Mary, University of London, UKZhihai Xiang, Tsinghua University, ChinaXiang-Tuan Xiong, Northwest Normal University, ChinaDinghua Xu, Zhejiang Sci-Tech University, ChinaYongzhi Steve Xu, University of Louisville, USAJiaqing Yang, Chinese Academy of Sciences, ChinaJian Zhang, Sichuan Normal University, ChinaYing Zhang, Fudan University, ChinaTing Zhou, University of Washington, USAJianxin Zhu, Zhejiang University, China Advisory BoardH Thomas Banks, North Carolina State University, USATony F Chan, The Hong Kong University of Science and Technology, HKSARHeinz W Engl, Johannes Kepler Universitát Linz, AustriaRainer Kress, Georg-August-Universitát G

  9. Empirical Evidence of Social and Emotional Learning's Influence on School Success: A Commentary on "Building Academic Success on Social and Emotional Learning: What Does the Research Say?," a Book Edited by Joseph E. Zins, Roger P. Weissberg, Margaret C. Wang, and Herbert J. Walberg

    ERIC Educational Resources Information Center

    Taylor, Rebecca D.; Dymnicki, Allison B.

    2007-01-01

    In Building Academic Success on Social and Emotional Learning: What does the Research Say? Zins and his colleagues presented a new way to conceptualize the impact of social and emotional learning programs on students' school success by broadening the concept to include students' attitudes, behaviors, and performance. To build on Zins' ideas, we…

  10. Comment on "Cenozoic tectonic deformation and uplift of the South Tian Shan: Implications from magnetostratigraphy and balanced cross-section restoration of the Kuqa depression" by Tao Zhang, Xiaomin Fang, Chunhui Song, Erwin Appel, and Yadong Wang [Tectonophysics, 2014, doi:10.1016/j.tecto.2014.04.044

    NASA Astrophysics Data System (ADS)

    Qiao, Qingqing; Huang, Baochun; Piper, John D. A.

    2016-10-01

    The recent paper entitled: "Cenozoic tectonic deformation and uplift of the South Tian Shan: Implications from magnetostratigraphy and balanced cross-section restoration of the Kuqa depression" by Zhang et al. [Tectonophysics, 2014, doi:10.1016/j.tecto.2014.04.044] discusses the Cenozoic tectonic deformation and uplift of the South Tianshan Mountains by integrating tectonic investigations, seismostratigraphic analysis and paleomagnetic dating of the thrust-fold belt in the Kuqa Depression at the southern border of the Tianshan. To support their conclusions the authors have reinterpreted a high resolution magnetostratigraphic study of the Kezilenuer Section in a paper entitled "Magnetostratigraphic study of the Kuche Depression, Tarim Basin, and Cenozoic uplift of the Tian Shan Range, Western China" by Huang et al. [Earth and Planetary Science Letters Volume 251, pages 346-364 (2006)]. We note here (i) that apparent conflicts in definition of the Xiyu Formation in the Kuche Depression as proposed by Zhang et al. (2014) require amplification and (ii) argue that their age assignment for the Kezilenuer Section is incorrect and yields an anomalously low sedimentation rate for the infilling of this foreland basin.

  11. Effects of ice storm on forest ecosystem of southern China in 2008 Shaoqiang Wang1, Lei Zhou1, Weimin Ju2, Kun Huang1 1Key Lab of Ecosystem Network Observation and Modeling, Institute of Geographical Sciences and Natural Resources Research, Beijing, 10010

    NASA Astrophysics Data System (ADS)

    Wang, Shaoqiang

    2014-05-01

    Evidence is mounting that an increase in extreme climate events has begun to occur worldwide during the recent decades, which affect biosphere function and biodiversity. Ecosystems returned to its original structures and functions to maintain its sustainability, which was closely dependent on ecosystem resilience. Understanding the resilience and recovery capacity of ecosystem to extreme climate events is essential to predicting future ecosystem responses to climate change. Given the overwhelming importance of this region in the overall carbon cycle of forest ecosystems in China, south China suffered a destructive ice storm in 2008. In this study, we used the number of freezing day and a process-based model (Boreal Ecosystem Productivity Simulator, BEPS) to characterize the spatial distribution of ice storm region in southeastern China and explore the impacts on carbon cycle of forest ecosystem over the past decade. The ecosystem variables, i.e. Net primary productivity (NPP), Evapotranspiration (ET), and Water use efficiency (WUE, the ratio of NPP to ET) from the outputs of BEPS models were used to detect the resistance and resilience of forest ecosystem in southern China. The pattern of ice storm-induced forest productivity widespread decline was closely related to the number of freezing day during the ice storm period. The NPP of forest area suffered heavy ice storm returned to normal status after five months with high temperature and ample moisture, indicated a high resilience of subtropical forest in China. The long-term changes of forest WUE remain stable, behaving an inherent sensitivity of ecosystem to extreme climate events. In addition, ground visits suggested that the recovery of forest productivity was attributed to rapid growth of understory. Understanding the variability and recovery threshold of ecosystem following extreme climate events help us to better simulate and predict the variability of ecosystem structure and function under current and future climate change.

  12. Climatic and Hydrologic Modeling in the Yellow River Basin in China Dr. Shourong Wang wangsr@cma.gov.cn China Meteorological Administration No.46, Zhongguancun Nandajie, Haidian District, Beijing 100081, China Dr. Ruby LEUNG, Pacific Northwest National Laboratory, Richland, Washington 99352, USA

    NASA Astrophysics Data System (ADS)

    Wang, S.

    2012-12-01

    In order to enhance climatic and hydrologic prediction and assessment ability in the Yellow River Basin, the climatic and hydrologic modeling system is developed based on a joint international research. The system includes three sub-modeling systems, the seasonal climatic modeling system, the climate change modeling system, and the hydrologic modeling system. The seasonal climatic modeling system is composed of a regional climate model WRF3.3.1 developed by PNNL in 2011, with domain cover whole China and surrounding areas and horizontal resolution of 30 km, the Global general circulation models (GCMs) developed by China National Climate Center (NCC), providing lateral boundary conditions to WRF3.3.1, and both dynamic and statistic downscaling tools for providing detail modeling results in the Yellow River Basin. The climate change modeling system is composed of a regional climate model RegCM4.0 modified by NCC, with domain and horizontal resolution similar to WRF3.3.1, four GCMs MIROC3.2, ECHAM5, HadCM3 and NCC-CSM1.1, providing lateral boundary conditions to RegCM4.0, respectively, for comparing the nest modeling results, and also the downscaling tools. The hydrologic modeling system is composed of a large scale semi-distributed hydrologic mode VIC(Variable Infiltration Capacity) modified by PNNL, with domain cover whole Yellow River Basin and horizontal resolution of 50 km, and a distributed hydrologic mode DHSVM3.0 (Distributed Hydrology-Soil-vegetation Mode) also modified by PNNL, with domain cover the headstream of Yellow River Basin and horizontal resolution of 0.5 km. Both VIC and DHSVM3.0 are driven by the outputs of WRF3.3.1 and RegCM4.0, and provide seasonal hydrologic predictions and future hydrologic projections under IPCC AR5 climate change scenarios SRES RCP8.5 and RCP4.5. Now the simulated seasonal climatic and hydrologic results are compared and verified by recorded data sets, and VIC and DHSVM3.0 are running for the future hydrologic simulation driven by climate change modeling outputs.

  13. Comments on X. Yin, A. Wen, Y. Chen, and T. Wang, `Studies in an optical millimeter-wave generation scheme via two parallel dual-parallel Mach-Zehnder modulators', Journal of Modern Optics, 58(8), 2011, pp. 665-673

    NASA Astrophysics Data System (ADS)

    Hasan, Mehedi; Maldonado-Basilio, Ramón; Hall, Trevor J.

    2015-04-01

    Yin et al. have described an innovative filter-less optical millimeter-wave generation scheme for octotupling of a 10 GHz RF oscillator, or sedecimtupling of a 5 GHz RF oscillator using two parallel dual-parallel Mach-Zehnder modulators (DP-MZMs). The great merit of their design is the suppression of all harmonics except those of order ? (octotupling) or all harmonics except those of order ? (sedecimtupling), where ? is an integer. A demerit of their scheme is the requirement to set a precise RF signal modulation index in order to suppress the zeroth order optical carrier. The purpose of this comment is to show that, in the case of the octotupling function, all harmonics may be suppressed except those of order ?, where ? is an odd integer, by the simple addition of an optical ? phase shift between the two DP-MZMs and an adjustment of the RF drive phases. Since the carrier is suppressed in the modified architecture, the octotupling circuit is thereby released of the strict requirement to set the drive level to a precise value without any significant increase in circuit complexity.

  14. EDITORIAL: Focus on Iron-Based Superconductors FOCUS ON IRON-BASED SUPERCONDUCTORS

    NASA Astrophysics Data System (ADS)

    Hosono, Hideo; Ren, Zhi-An

    2009-02-01

    -L Drechsler, N Kozlova, M Bartkowiak, J E Hamann-Borrero, G Behr, K Nenkov, H-H Klauss, H Maeter, A Amato, H Luetkens, A Kwadrin, R Khasanov, J Freudenberger, A Köhler, M Knupfer, E Arushanov, H Rosner, B Büchner and L Schultz Low-energy spin dynamics in the antiferromagnetic phase of CaFe2As2 N J Curro, A P Dioguardi, N ApRoberts-Warren, A C Shockley and P Klavins Muon spin rotation study of magnetism and superconductivity in BaFe2-xCoxAs2 and Pr1-xSrxFeAsO C Bernhard, A J Drew, L Schulz, V K Malik, M Rössle, Ch Niedermayer, Th Wolf, G D Varma, G Mu, H-H Wen, H Liu, G Wu and X H Chen Magnetic impurities in the pnictide superconductor Ba1-xKxFe2As2 Sutirtha Mukhopadhyay, Sangwon Oh, A M Mounce, Moohee Lee, W P Halperin, N Ni, S L Bud'ko, P C Canfield, A P Reyes and P L Kuhns Neutron scattering investigation of the magnetic order in single crystalline BaFe2As2 M Kofu, Y Qiu, Wei Bao, S-H Lee, S Chang, T Wu, G Wu and X H Chen An NMR study on the F-doping evolution of the iron oxypnictide LaFeAs(O1-xFx) Y Nakai, S Kitagawa, K Ishida, Y Kamihara, M Hirano and H Hosono The peculiar physical properties and phase diagram of BaFe2-xCoxAs2 single crystals X F Wang, T Wu, G Wu, R H Liu, H Chen, Y L Xie and X H Chen Synthesis of LnFeAsO1-y superconductors (Ln=La and Nd) using the high-pressure technique Kiichi Miyazawa, Kunihiro Kihou, Motoyuki Ishikado, Parasharam M Shirage, Chul-Ho Lee, Nao Takeshita, Hiroshi Eisaki, Hijiri Kito and Akira Iyo Correlation effects in the iron pnictides Qimiao Si, Elihu Abrahams, Jianhui Dai and Jian-Xin Zhu Competition/coexisitence of magnetism and superconductivity in iron pnictides probed by muon spin rotation Soshi Takeshita and Ryosuke Kadono Impurity-induced in-gap state and Tc in sign-reversing s-wave superconductors: analysis of iron oxypnictide superconductors Yuko Senga and Hiroshi Kontani Intrinsic magnetic properties of the superconductor NdFeAsO0.9F0.1 from local and global measurements R Prozorov, M E Tillman, E D Mun and P C Canfield

  15. Design, Fabrication and Characterization of Indefinite Metamaterials of Nanowires

    DTIC Science & Technology

    2011-01-01

    doi: 10.1098/rsta.2011.0159 , 3434-3446369 2011 Phil. Trans. R. Soc. A Angelica M. Stacy, Yuh-Lin Wang and Xiang Zhang Jie Yao, Yuan Wang, Kun-Tong...YIN1,4, GUY BARTAL1, ANGELICA M. STACY5, YUH-LIN WANG2,6 AND XIANG ZHANG1,4,* 1National Science Foundation (NSF ) Nanoscale Science and Engineering Center

  16. Integrated Automated Analyzer for Monitoring of Explosives in Groundwater

    DTIC Science & Technology

    2003-11-01

    3. Lin, Y., Wang, J.; Pumera , M.; Chatrathi, M. P.; Escarpa, A.; Musameh, M.; Collins, G.; Mulchandani, A. “Microchip for Fast Screening and...Orlando, FL. 4. Wang, J.; Pumera , M.; Collins, G. E.; Mulchandani, A.; Lin, Y.; Olsen, K. “Single- Channel Microchip for Fast Screening and Detailed...Sciences Laboratory, Pacific Northwest National Laboratory Joseph Wang, Martin Pumera , Madhu Prakash Chatrathi, Alberto Escarpa, Mustafa Musameh

  17. Better Steganalysis (BEST) - Reduction of Interfering Influence of Image Content on Steganalysis

    DTIC Science & Technology

    2009-10-08

    2008. [4] Sorina Dumitrescu, Xiaolin Wu, and Zhe Wang . Detection of LSB steganography via sample pair analysis. In Fabien A. P. Petitcolas, editor...Xiaolin Wu, and Zhe Wang . Detection of LSB steganography via sample pair analysis. IEEE Trans. of Signal Processing, 51:1995–2007, 2003. [6] Jessica...Berlin Heidelberg, 2000. Springer-Verlag. [27] Xiaoyi Yu, Yunhong Wang , and Tieniu Tan. On estimation of secret message length in Jsteg-like

  18. Chinese Crisis Decision Making: Using a Cybernetic Approach to Interpret and Predict Beijing’s Behavior Under Stress

    DTIC Science & Technology

    2010-03-01

    Deputy Secretary of CDIC He Yong, Director of the Central Committee Policy Research Office Wang Huning, and the Director of the General Office Ling...specialist briefings to support central leadership decision-making forums. Wang Huning, a well-known college debate champion and holdover from the...Liangyu, Vice Premier for Industry and Energy Zhang Dejiang, and Vice Premier of Finance Wang Qishan—and five state councilors including Minister

  19. Static Extraction and Conformance Analysis of Hierarchical Runtime Architectural Structure

    DTIC Science & Technology

    2010-05-14

    Wang , and Zhe Yang. Modular Checking for Buffer Over- flows in the Large. In Intl. Conf. on Software Engineering, pages 232–241, 2006. Irit Hadar and...1997; Wang et al. 2003; Raghavan et al. 2004), or under additional assumptions, e.g., (Torsello et al. 2005). Insertions and deletions only. Many...based on variants of the A* algorithm (Messmer 1996), do not scale beyond a few dozen nodes (Hlaoui and Wang 2002). In the context of architectural views

  20. Advanced Techniques for Scene Analysis

    DTIC Science & Technology

    2010-06-01

    provide segmentation of the flow field. Wang and Adelson described in [21] a method to represent moving objects using sets of overlapping layers. The... Wang and E. H. Adelson, “Representing moving images with layers,” in Image Processing, IEEE Transactions on, Sep 1994, pp. 625–638. [22] Y. A. G. D...B. Han, C. Paulson, J. Wang , and D. Wu, “Depth-based image registration,” in Proceedings of SPIE Defense & Security Symposium, vol. 7699, Orlando

  1. China and Proliferation of Weapons of Mass Destruction and Missiles: Policy Issues

    DTIC Science & Technology

    2009-12-23

    Wang , Beijing, October 31, 2004; Xinhua, Beijing, November 5, 2004; IRNA, Tehran, November 6, 2004; Xinhua, Beijing, November 8, 2004 (via FBIS). 24...February 12). China also pointed to North Korea and the United States as the two key parties to hold bilateral talks. Wang Jiarui, Director of the...Department official Sung Kim’s visit to Pyongyang in late January/early February, Wang Jiarui, Director of the International Department of the

  2. U.S. Strategy in Afghanistan-Pakistan: Chinese Views and Interests

    DTIC Science & Technology

    2010-09-01

    Daobao (liH^^t SE^ffi), article by Wang Shida, researcher at CICIR, December 10, 2010. Open Source Center CPP20100304671001. IAAt least one...long-term economic and security interests could suffer if China remains passive in the region while "hiding behind 44 Wang Shida, "PRC Daily Article...Suggests Things China Should Do in Afghanistan." 45 Beijing also replaced the long-serving, hard-line Party Secretary for Xinjiang, Wang Lequan, with

  3. China and Proliferation of Weapons of Mass Destruction and Missiles: Policy Issues

    DTIC Science & Technology

    2010-08-16

    September 23, 2009; Reuters, April 14, 2010; Reuters, August 11, 2010. 22 Zhongguo Wang , Beijing, October 31, 2004; Xinhua, Beijing, November 5, 2004; IRNA...China also pointed to North Korea and the United States as the two key parties to hold bilateral talks. Wang Jiarui, Director of the International...Pyongyang in late January/early February, Wang Jiarui, Director of the International Department of the Communist Party of China, traveled to Pyongyang and

  4. China and Proliferation of Weapons of Mass Destruction and Missiles: Policy Issues

    DTIC Science & Technology

    2009-07-27

    Dongfang Zaobao, December 11, 2007; Xinhua, January 14, 2009; AP, March 14, 2009; Reuters, June 3 and 4, 2009. 21 Zhongguo Wang , Beijing, October 31...Secretary of State Rice on February 12). China also pointed to North Korea and the United States as the two key parties to hold bilateral talks. Wang ...to Pyongyang in late January/early February, Wang Jiarui, Director of the International Department of the Communist Party of China, traveled to

  5. Behavior of Machine Learning Algorithms in Adversarial Environments

    DTIC Science & Technology

    2010-11-23

    Computer Science, pages 226–248. Springer, September 2006. ISBN 3-540-39723-X. Zhe Wang , William K. Josephson, Qin Lv, Moses Charikar, and Kai Li. Filtering...take significantly more time than text-based filtering [Dredze et al., 2007, Wang et al., 2007]. An attacker could exploit such overhead by sending...generalize, such as through regularization. Wang et al. [2006] present Anagram, an anomaly detection system using n-gram models of bytes to detect intrusions

  6. China and Proliferation of Weapons of Mass Destruction and Missiles: Policy Issues

    DTIC Science & Technology

    2012-03-30

    reactor in Pakistan from June 2006 to March 2007. Later, on June 16, 2011, authorities in Atlanta arrested Wang Xun, a PRC national and U.S. resident...On November 16, the Commerce Department ordered sanctions against Wang . The “Section 721 Report” for 2011 continued to report that PRC entities...2010; Caixin Wang , August 19, 2010; Washington Post, October 18, 2010; Reuters, October 28, 2010; Tehran Times, April 23, 2011; Reuters, June 17

  7. Large Scale Visual Recognition

    DTIC Science & Technology

    2012-06-01

    Sanjeev Satheesh, and Hao Su. I thank my colleagues, Barry Chai, Jia Li, Juan Carlos Niebles, Olga Russakovsky, Min Sun, Zhe Wang , and Bangpeng Yao...Fergus et al. explore semi-supervised learning on 126 hand labeled Tiny Images categories [83] and Wang et al. show classification on a maximum of 315...natural scene categories. In: CVPR06. (2006) [16] Wang , J., Yang, J., Yu, K., Lv, F., Huang, T., Gong, Y.: Locality-constrained linear coding for image

  8. Differential Alterations in Excitatory and Inhibitory Networks Involving Dentate Granule Cells Following Chronic Treatment with Distinct Classes of NMDAR Antagonists in Hippocampal Slice Cultures

    DTIC Science & Technology

    2010-03-08

    to average 1 hour per response, including the time for reviewing instructions, searching existing data sources, gathering and maintaining the data ...encouragement when things got tough. I would like to acknowledge Dr. Yu Dong and Dr. Xiao-Min Wang for providing seizure data and Dr. Wang Yu for providing...immunohistochemistry data . I would like to thank my former colleagues, Dr. Yu Dong, Dr. Yelena Petrova, Dr. Yingbing Liu, Dr. Yu Wang, Ms

  9. Characterization, Modeling, and Accelerating Emulation of Aircraft Coating Exposure and Degradation

    DTIC Science & Technology

    2009-09-30

    Maocheng Yan Stuart Croll Jun Nie Jinhai Wang Dennis Tallman Quan Su Yechung Wang Kerry Allahar Andrew Huovinen Duhua Wang Brian Hinderliter...than may natural weathering. Thus coating failure due to adhesion loss or hydrolysis can be very different between accelerated testing protocols... Kerry Allahar and Brian Hinderliter. Some of the results are discussed above. The results of these studies are also discussed in detail in the

  10. Connecting your Apple to Octopus 7600's

    SciTech Connect

    Barton, G.W. Jr.

    1983-01-17

    In UCID-19588, Communicating between the Apple and the Wang, we described how to take Apple DOS text files and send them to the Wang, and how to return Wang files to the Apple. It is also possible to use your Apple as an Octopus terminal, and to exchange files with Octopus 7600's. Presumably, you can also talk to the Crays, or any other part of the system. This connection has another virtue. It eliminates one of the terminals in your office.

  11. Terahertz (THZ) Imaging

    DTIC Science & Technology

    2006-03-01

    robust and low-cost system. 6. Ferguson , B.; Wang, S.; Xi, J.; Gray, D.; Abbott, D.; Zhang, X.-C.; “Linearized inverse scattering for three...about the possibilities of long range terahertz imaging with the same lens. 9. Wang, S.; Ferguson , B.; Zhong, H.; Zhang, X.-C.; “Three...profile of powders is also demonstrated. 16. Ferguson , B.; Wang, S.H.; Abbott, D.; Zhang, X.-C.; “T-ray tomographic imaging” IEEE Tenth International

  12. The IEEE International Conference on Data Mining (10th) Held in Sydney, Australia on 14-17 December 2010

    DTIC Science & Technology

    2010-12-17

    on the Deep Web Tantan Liu, Fan Wang, and Gagan Agrawal q Learning Markov Network Structure with Decision Trees Daniel Lowd and Jesse Davis q Towards...Understanding Wang, Fan q Stratified Sampling for Data Mining on the Deep Web Wang, Fei q Learning a Bi-Stochastic Data Similarity Matrix Prev Home Next Papers by...Networks Aggarwal, Charu q Addressing Concept-Evolution in Concept-Drifting Data Streams Agrawal, Gagan q Stratified Sampling for Data Mining on the Deep

  13. JPRS Report, China.

    DTIC Science & Technology

    1988-09-02

    Deputy Director Wang Yongjun [3769 3057 6874] of the Foreign Investment Administration of the Ministry of Foreign Economic Relations and Trade came...fall, while on the other hand the amount of actual capital input showed slow growth. What was the cause of this? Deputy Director Wang Yongjun ...this, Deputy Director Wang Yongjun believes that construction of these tourist ser- vice facilities is necessary, since in order for foreign

  14. Precipitation Phenomena: Deformation and Aging. Proceedings of an International Conference Held in Conjunction with the 1988 World Materials Congress, Chicago, Illinois, USA, 24-30 September 1988

    DTIC Science & Technology

    1988-01-01

    Multiphase Stainless Steels ....... 35 F. D. S. Marquis, S. F. Wang , J. Qadri, M. Hadji, M. N. Datar Precipitating of Second Phase in Solid Solutions...AGING BEHAVIOR OF DOUBLE QUENCHED AND COLD WORKED MULTIPHASE STAINLESS STEELS F. D. S. Marquis, S. F. Wang , J. H. Qadri, M. Hadji, M. N. Datar Department...noticeable. REFERENCES [1] Zhou Huijiu, Wang Xiaotian, Huang Mingzhi aid Lou Qifu, Scientific Journal of Higher Educational Institution, Mechanical Engineering

  15. Reliability-Based Performance Assessment of Damaged Ships

    DTIC Science & Technology

    2006-10-01

    SNAME, Arlington Virginia, II.B. 1-mII.B. 19, 1991. Wang , Ge; Chen, Yongjun ; Zhang, Hanqing; Peng, Hua. (2002). "Longitudinal strength of ships with...strength of hull girders of damaged ships. Reliability of the ship was also estimated by a first order and second moment method. Wang , et al (2002...to achieve a safe design. Wang (1996) have applied several methods, such as point- crossing method, load coincidence method, Ferry Borges method, peak

  16. JPRS Report, Science & Technology, China.

    DTIC Science & Technology

    2007-11-02

    4, Oct 92] 27 System Management Program Implementation of a Reconfigurable Double-Computer System at Module Level [ Wang Shuhua; ZHONGGUO...Application in Pattern Recognition [Liu Liren, Wang Tianji; GUANGXUE XUEBAO, Sep 92] 40 Calculation of Heterojunction Conduction Band for Field...for 77K Operation [Zheng Jiang, Wang Shu, et al; DIANZIXUEBAO, Aug 92] 44 In-Situ Formation of YBaCuO Superconducting Film by Long-Pulse Laser

  17. The Hueckel Model for Small Metal Clusters. 3. Anion Structures and HMO (Hueckel Molecular Orbital) Electron Affinities.

    DTIC Science & Technology

    1987-04-01

    Electron Affinities by S N Lindsay, Lin Chu, Youqi Wang and Thomas F. George Prepared fur Publication 1in Journal of Chemical Physics 5epartments of...Affinities. 12. PERSONAL AUTIHORiS) D. M. LIndsay, L. Chu, Y. Wang and Thomas F. George 13. TYPE OF REPORT 13b. TIME COVERED vid. OATE OF REPORT fVro .1o...New York, New York 10031 Youqi Wang Department of Chemistry California Institute of Technology Pasadena, Califonia 91125 Thomas IF. Georg Departments

  18. The Hueckel Model for Small Metal Clusters. 4. Orbital Properties and Cohesive Energies for Model Clusters of Up to Several Hundred Atoms

    DTIC Science & Technology

    1989-12-01

    Cohesive Energies for Model Clusters of Up to Several Hundred Atoms by D. M. Lindsay, Youqi Wang and Thomas F. George Prepared for Publication in... Wang , Thomas F. George 13a. TYPE OF REPORT 13b. TIME COVERED 114. DATE OF REPORT (Year, Month, Day) 15. PAGE COUNT FROM TO December 1989 34 16... Wang y ........ Department of Chemistry California Institute of Technology Pasadena, California 91125 Dist Thomas F. George (hi Departments of Chemistry

  19. Hybrid protocol of remote implementations of quantum operations

    NASA Astrophysics Data System (ADS)

    Zhao, Ning Bo; Wang, An Min

    2007-12-01

    We propose a protocol of remote implementations of quantum operations by hybridizing bidirectional quantum-state teleportation (BQST) [Huelga , Phys. Rev. A 63, 042303 (2001)] and the Wang protocol [Wang, Phys. Rev. A 74, 032317 (2006)]. The protocol is available for remote implementations of quantum operations in the restricted sets specified in the paper. We also give a proof of the protocol and point out its optimization. As an extension, this hybrid protocol can be reduced to the BQST and Wang protocols.

  20. 76 FR 554 - Ocean Transportation Intermediary License Applicants

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-05

    .... Officers: Jerry Wang, Vice President (Qualifying Individual), Loong H. Chang, President/Director... Raymond, CEO. Application Type: New NVO & OFF License. Toshiba Logistics America, Inc. (NVO & OFF),...

  1. JPRS Report, China, Qiushi Seeking Truth, No. 16, 16 August 1989

    DTIC Science & Technology

    1989-10-04

    Socialist Orientation—A Speech Delivered to the National Work Conference of Institutes of Higher Education on 15 July 1989 [ Li Tieying] 1 Some...an Extremely Small Number of People Want? [ Li Jian] 10 Only the Socialist System Can Develop China [ Li Chengrui] 17 To Strengthen Leadership...of the Republic [ Li Wenbin; not translated] 36 Hesitation of’Private Letter-Writers’ [Ren Quanliang; not translated] 36 JPRS-CAR-89-100 4

  2. Shaping the Future: Security Cooperation to Shape Chinese Diplomacy in the South Pacific

    DTIC Science & Technology

    2008-10-31

    Rogers, “Dragon with a Heart of Darkness ? Countering Chinese Influence in Africa,” Joint Forces Quarterly 47, (4th quarter 2007), 22. 3. U.S...accessed 27 October 2008). “Papua New Guinea is a country of destination for women and children from Malaysia , the Philippines, Thailand, and China...Solomon Islands lumber, no other Chinese business ventures, such as tourism , have significant enough economic impact to mention. 47. Jian Yang

  3. Naval War College Review. Volume 64, Number 2, Spring 2011

    DTIC Science & Technology

    2011-01-01

    MRBMs and hundreds of ARMs and LACMs, and it has armed nearly every boat, ship, submarine, and aircraft in its navy with super - sonic ASCMs. Moreover...several years. As of November 2010, China has thirty optical, synthetic aperture radar (SAR), IR, and multispectral intelligence satellites in orbit . The...PLA also operates three JianBing 3 and twelve YaoGan surveillance satellites, and several additional YaoGan platforms are expected in orbit each year

  4. Neuroimaging of Brain Injuries and Disorders at Cleveland Clinic

    DTIC Science & Technology

    2013-12-01

    SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT 18. NUMBER OF PAGES 19a. NAME OF RESPONSIBLE PERSON a. REPORT U b. ABSTRACT U c...5 of 12 We established minimum performance criteria and minimum motion limits for fMRI, rs-fMRI and DTI as described in Lowe et al. (2008) for...Stephen Rao Mark Lowe Ken Sakaie Stephen Jones Michael Parsons Erik Beall Michael Phillips Jian Lin Christine Reece Alex Bura Juliet Schulz

  5. Correlation of Mechanical Properties in Bulk Metallic Glasses with 27Al NMR Characteristics

    DTIC Science & Technology

    2011-12-01

    properties Magdalena T SANDOR , Laszlo J KECSKES , Qiang HE , Jian XU , Yue WU University of North Carolina - Chapel Hill Office of Sponsored...doi: 10.1007/s11434-011-4834-z Correlation of mechanical properties in bulk metallic glasses with 27Al NMR characteristics SANDOR Magdalena T1...bulk metallic glass, nuclear magnetic resonance, knight shift, magnetic susceptibility, mechanical properties Citation: Sandor M T, Kecskes L J

  6. Relationship of Personality Factors and Some Social Habits to Cardiovascular Risk in Submariners

    DTIC Science & Technology

    1982-01-01

    likely to develop coronary heart disease chasthenia, schizophrenia , .’nd social introversion. On the other (CHD) during their life span than those with the...ob- tain a favorable image if sufficient numbers of quality sessive thoughts: schizophrenia (Sc). withdrawal trends men are to be attracted to and...identified by the three MMPI scales: psychas- thenla, schizophrenia , and social introversion. On the other hand, the scales most D D I JiAN721 1473 EDITION

  7. Real-Time Ballistic Impact Deformation and Strain Measurements of Transparent TROGAMID Polyamides

    DTIC Science & Technology

    2011-09-01

    Real-Time Ballistic Impact Deformation and Strain Measurements of Transparent TROGAMID Polyamides by Alex J. Hsieh, Jian H. Yu, and John W...5069 ARL-TN-449 September 2011 Real-Time Ballistic Impact Deformation and Strain Measurements of Transparent TROGAMID Polyamides ...September 2010–May 2011 4. TITLE AND SUBTITLE Real-Time Ballistic Impact Deformation and Strain Measurements of Transparent TROGAMID Polyamides 5a

  8. Teaching Bitter Lessons: China’s Use of Force in Territorial Disputes 1962-1988

    DTIC Science & Technology

    2013-06-01

    19 Harry Gelman and Rand Corporation, The Soviet Far East Buildup and Soviet Risk- taking Against China (Rand, 1982), 8. 20 Jian...The Sino-Soviet Border Dispute.” 29 Gelman and Corporation, The Soviet Far East Buildup and Soviet Risk-taking Against China, 19. 30 Fravel...Selected Diplomatic Papers of Zhou Enlai]. Beijing: Zhongyang wexian chubanshe, 1990. Gelman , Harry, and Rand Corporation. The Soviet Far East Buildup

  9. Innovative Design and Processing of Multi-Functional Adaptive Structural Materials

    DTIC Science & Technology

    2014-01-09

    Christian Punckt, Michael Bozlar, Sibel Korkut, Jian Zhu, Choon Chiang Foo, Zhigang Suo, Ilhan A. Aksay. Dielectric elastomer actuators with...Saraf, Dehong Hu, Jiguang Zhang, Gordon L. Graff, Jun Liu, Michael A. Pope, Ilhan A. Aksay. Ternary Self-Assembly of Ordered Metal Oxide?Graphene...Garay, , P.J. Thurner, , J. Seto,, B. Mayzel, , L. Jon Friesen , , B.F. Chmelka, , P. Fratzl, , J. Aizenberg, , Y. Dauphin, , D. Kisailus,, D.E

  10. Time-Domain Finite Element Analysis of Nonlinear Breakdown Problems in High-Power-Microwave Devices and Systems

    DTIC Science & Technology

    2015-12-24

    radiation , the electrons in the HPM device are accelerated by the high-intensity electromagnetic fields. The motion of electrons produces impact on...The radiation and shielding of the electromagnetic fields by the oscillating plasma can be observed in Figure 16(c), where the two plots are...DEVICES AND SYSTEMS Su Yan and Jian-Ming Jin University of Illinois Center for Computational Electromagnetics Department of Electrical and Computer

  11. JPRS Report China

    DTIC Science & Technology

    1988-11-07

    tests . My friend’s complaints about the "difficulty of teach- ing" were actually not totally unheard of. My son is in high school. His political...assessment of a testing nature, the general mark was "excellent." Careful Department Director Li Guang- jian organized personnel to make a spot check...The examining officers went to 3 regiments, where they tested a row of 13 examinees, and in no case was there nitpicking. Conclusion: It is feasible

  12. JPRS Report, Science & Technology, China

    DTIC Science & Technology

    2007-11-02

    photographs of Party, he became even more dedicated to the cause of the flow field behind its tail section. His mission was to developing China’s...aeronautical industry. Today, even discover the cause of flutter which had prevented the though already in his golden years, he still holds posi- Jian-8 from...monitoring. This system provides data on faults in equipment at Qinghua University, and using about 70 satellite attitude control via fault/ cause -and

  13. Normal and Feature Approximations from Noisy Point Clouds

    DTIC Science & Technology

    2005-02-01

    Normal and Feature Approximations from Noisy Point Clouds Tamal K. Dey Jian Sun Abstract We consider the problem of approximating normal and...normal and, in partic- ular, feature size approximations for noisy point clouds . In the noise-free case the choice of the Delaunay balls is not an issue...axis from noisy point clouds ex- ists [7]. This algorithm approximates the medial axis with Voronoi faces under a stringent uniform sampling

  14. Next Generation Proton Beam Writing: A Platform Technology for Nanowire Integration

    DTIC Science & Technology

    2010-06-01

    silsesquioxane (HSQ) nanostructures for Nickel electroplating, S. Gorelick, F. Zhang, P.G. Shao, J.A. van Kan, Harry J . Whitlow, F. Watt, Nuclear...Yaping Ren, Jeroen Anton van Kan, Sher-Yi Chiam, Linke Jian, Herbert O. Moser, Thomas Osipowicz, Frank Watt, Nuclear Instruments & Methods in Physics...Research Section B Volume 267 (2009) 2376-2380 2 Proton beam writing: a platform technology for nanowire production, J . A. van Kan F. Zhang S. Y

  15. The Next Generation Focusing Lenses for Proton Beam Writing

    DTIC Science & Technology

    2009-07-28

    nanostructures for Nickel electroplating, S. Gorelick, F. Zhang, P.G. Shao, J.A. van Kan, Harry J . Whitlow, F. Watt, Nuclear Instruments & Methods in Physics...Anton van Kan, Sher-Yi Chiam, Linke Jian, Herbert O. Moser, Thomas Osipowicz, Frank Watt, Nuclear Instruments & Methods in Physics Research Section B...Volume 267 (2009) 2376-2380 2 Proton beam writing: a platform technology for nanowire production, J . A. van Kan F. Zhang S. Y. Chiam T. Osipowicz A

  16. Nitrate reductase-mediated early nitric oxide burst alleviates oxidative damage induced by aluminum through enhancement of antioxidant defenses in roots of wheat (Triticum aestivum).

    PubMed

    Sun, Chengliang; Lu, Lingli; Liu, Lijuan; Liu, Wenjing; Yu, Yan; Liu, Xiaoxia; Hu, Yan; Jin, Chongwei; Lin, Xianyong

    2014-03-01

    • Nitric oxide (NO) is an important signaling molecule involved in the physiological processes of plants. The role of NO release in the tolerance strategies of roots of wheat (Triticum aestivum) under aluminum (Al) stress was investigated using two genotypes with different Al resistances. • An early NO burst at 3 h was observed in the root tips of the Al-tolerant genotype Jian-864, whereas the Al-sensitive genotype Yang-5 showed no NO accumulation at 3 h but an extremely high NO concentration after 12 h. Stimulating NO production at 3 h in the root tips of Yang-5 with the NO donor relieved Al-induced root inhibition and callose production, as well as oxidative damage and ROS accumulation, while elimination of the early NO burst by NO scavenger aggravated root inhibition in Jian-864. • Synthesis of early NO in roots of Jian-864 was mediated through nitrate reductase (NR) but not through NO synthase. Elevated antioxidant enzyme activities were induced by Al stress in both wheat genotypes and significantly enhanced by NO donor, but suppressed by NO scavenger or NR inhibitor. • These results suggest that an NR-mediated early NO burst plays an important role in Al resistance of wheat through modulating enhanced antioxidant defense to adapt to Al stress.

  17. Chromatographic fingerprint analysis and simultaneous determination of eight lignans in Justicia procumbens and its compound preparation by HPLC-DAD.

    PubMed

    Wang, Linan; Pan, Jianyu; Yang, Meihua; Wu, Jun; Yang, Junshan

    2011-03-01

    HPLC fingerprints were developed for the quality evaluation of Justicia procumbens and its compound preparation, Jian-er syrup, together with the simultaneous quantification of eight arylnaphthalide lignans (6'-hydroxy justicidin B, 6'-hydroxy justicidin A, 6'-hydroxy justicidin C, justicidin B, chinensinaphthol methyl ether, justicidin C, taiwanin C, and neojusticin A). Samples were separated with a Shiseido Capcell Pak C(18) reversed-phase column (250×4.6 mm id, 5 μm) using acetonitrile and water as the mobile phase. The column temperature was maintained at 35°C and the wavelength of detector was set at 256 nm. For fingerprint analysis, 17 peaks were selected as the characteristic peaks for the evaluation of the similarities among different J. procumbens samples collected in different places. The structures of lignans were confirmed by diagnostic fragments in the positive ESI-MS(n) . The new method was successfully applied for the chromatographic fingerprint analysis and simultaneous determination of eight lignans in its compound preparation, Jian-er syrup. All the results indicated that HPLC fingerprint assay in combination with multi-marker determination afforded a useful method for the quality control of J. procumbens and its compound preparation, Jian-er syrup.

  18. Two new and one newly recorded species of Polypedilum Kieffer 1912 with DNA barcodes from Oriental China (Chironomidae: Diptera).

    PubMed

    Yan, Chuncai; Song, Chao; Liu, Ting; Zhao, Guangjun; Hou, Ziyuan; Cao, Wei; Wang, Xinhua

    2017-03-02

    Polypedilum (Tripodura) enshiense Song & Wang sp. n. and P. (Tripodura) jianfengense Song & Wang sp. n. are described and illustrated as male imagines from China. P. (Uresipedilum) paraconvictum Yamamoto, Yamamoto & Hirowatari, 2016 is recorded from China for the first time. Cytochrome coxidase subunit I (COI) sequence of above species are uploaded to Barcode of Life Data Systems (BOLD).

  19. The Religion of Learning English in "English": A Language Educator's Reading

    ERIC Educational Resources Information Center

    Gao, Xuesong

    2011-01-01

    This essay is my reading of "English," a novel based on author Wang Gang's experiences in Urumqi, Xinjiang Uyghur Autonomous Region, Northwest China during the Cultural Revolution (1966-1976). As a language educator, I was particularly interested in the way that Wang describes learning English in the novel. The essay focuses on three…

  20. Constrained Aeroacoustic Shape Optimization Using the Surrogate Management Framework

    DTIC Science & Technology

    2003-12-01

    412 A. L. Marsden, M. Wang & J. E. Dennis, Jr. rum for collaboration, as well as Charles Audet and Petros Koumoutsakos for valuable discussions...2003 Optimal aeroa- coustic shape design using the surrogate management framework. Submitted for review. MARSDEN, A. L., WANG, M. & KOUMOUTSAKOS , P

  1. Monaural Speech Segregation by Integrating Primitive and Schema-Based Analysis

    DTIC Science & Technology

    2008-02-03

    vol. 19, pp. 475-492. Wang D.L. and Chang P.S. (2008): An oscillatory correlation model of auditory streaming. Cognitive Neurodynamics , vol. 2, pp...Subcontracts DeLiang Wang (Principal Investigator) March 2008 Department of Computer Science & Engineering and Center for Cognitive Science The

  2. Results of a Randomized Controlled Trial of Student Success Skills

    ERIC Educational Resources Information Center

    Webb, Linda; Carey, John; Villares, Elizabeth; Wells, Craig; Sayer, Aline

    2014-01-01

    Numerous authors have reviewed research to determine which skills are considered fundamental to successful academic and social outcomes for students (Hattie, Briggs, & Purdie, 1996; Masten & Coatworth, 1998; Wang, Haertel, & Walberg, 1994; Zins, Weissberg, Wang, & Walberg, 2004). These skills include: (1) cognitive and…

  3. Ductilization of High-Strength Magnesium Alloys

    DTIC Science & Technology

    2012-09-17

    Wang thermodynamic model previously validated in high-performance steels . The calculations identify the cohesion enhancing potencies of grain boundary...thermodynamic model previously validated in high-performance steels . The calculations identify the cohesion enhancing potencies of grain boundary...boundary cohesion, based on the Rice-Wang thermodynamic model previously validated in high-performance steels . The calculations identify the cohesion

  4. Parameter Space Techniques for Robust Control System Design.

    DTIC Science & Technology

    1980-07-01

    been further investi- gated by Cruz [2] and Desoer and Wang [3]. In frequency design methods the concept to compensate the loop, such that high gains...of Feedback Systems, McGraw-Hill, New York, 1972. 3. C. A. Desoer and Y. T. Wang, "Foundations of Feedback Theory for Nonlinear Dynamical Systems

  5. Benchmarking Deep Networks for Predicting Residue-Specific Quality of Individual Protein Models in CASP11.

    PubMed

    Liu, Tong; Wang, Yiheng; Eickholt, Jesse; Wang, Zheng

    2016-01-14

    Quality assessment of a protein model is to predict the absolute or relative quality of a protein model using computational methods before the native structure is available. Single-model methods only need one model as input and can predict the absolute residue-specific quality of an individual model. Here, we have developed four novel single-model methods (Wang_deep_1, Wang_deep_2, Wang_deep_3, and Wang_SVM) based on stacked denoising autoencoders (SdAs) and support vector machines (SVMs). We evaluated these four methods along with six other methods participating in CASP11 at the global and local levels using Pearson's correlation coefficients and ROC analysis. As for residue-specific quality assessment, our four methods achieved better performance than most of the six other CASP11 methods in distinguishing the reliably modeled residues from the unreliable measured by ROC analysis; and our SdA-based method Wang_deep_1 has achieved the highest accuracy, 0.77, compared to SVM-based methods and our ensemble of an SVM and SdAs. However, we found that Wang_deep_2 and Wang_deep_3, both based on an ensemble of multiple SdAs and an SVM, performed slightly better than Wang_deep_1 in terms of ROC analysis, indicating that integrating an SVM with deep networks works well in terms of certain measurements.

  6. ALTERATION OF CARDIAC ELECTRICAL ACTIVITY BY WATER-LEACHABLE COMPONENTS OF RESIDUAL OIL FLY ASH (ROFA)

    EPA Science Inventory

    Alteration of cardiac electrical activity by water-leachable components
    of residual oil fly ash (ROFA)

    Desuo Wang, Yuh-Chin T. Huang*, An Xie, Ting Wang

    *Human Studies Division, NHEERL, US EPA
    104 Mason Farm Road, Chapel Hill, NC 27599
    Department of Basic ...

  7. Solar Magnetic Drivers of Space Weather

    DTIC Science & Technology

    1997-09-30

    Solar Physics Branch (Code 7660, Wang and Sheeley), the Air Force Phillips Lab (Space Effects Division, Kahler and Webb), NOAA Space Environment...eds. K. Balasubramaniam, J. Harvey, D. Rabin , ASP Conf. Ser. (San Francisco: ASP), in press. Y. M. Wang, N. R. Sheeley, Jr., K. P. Dere, R. T. Duffin

  8. A Unified Steganalysis Framework

    DTIC Science & Technology

    2013-04-01

    REFERENCES [1] Sorina Dumitrescu, Xiaolin Wu, and Zhe Wang , “Detection of lsb steganography via sample pair analysis,” in Information Hiding, Fabien A. P...that the proposed approach yield viable steganalyzer systems. REFERENCES [1] Dumitrescu, S., Wu, X., and Wang , Z., “Detection of lsb steganography via

  9. Model-Based Control using Model and Mechanization Fusion Techniques for Image-Aided Navigation

    DTIC Science & Technology

    2009-03-01

    sized helicopter, LQG control has also been utilized in controlling the same type of vehicle. Zhe Jiang, Jianda Han, Yuechao Wang , and Qi Song, from the...Han J. Wang Y., Z. and Q. Song. “Enhanced LQR Control for Unmanned Helicopter in Hover”. Proceedings of Systems and Control in Aerospace and As

  10. Antibody-Mediated BRCC36 Silencing: A Novel Approach for Targeted Breast Cancer Therapy

    DTIC Science & Technology

    2009-06-01

    complexes: new targets to overcome breast cancer radiation resistance. Expert Rev Anticancer Ther 6(2):187-96. Chen X, Arciero CA, Wang C, Broccoli D...1752s- 1756s. Chen X, Arciero CA, Wang C, Broccoli D, Godwin AK (2006). BRCC36 is essential for ionizing radiation-induced BRCA1 phosphorylation

  11. BRCA1-Associated Protein BRCC36: A Novel Target for Breast Cancer Therapy

    DTIC Science & Technology

    2008-10-01

    Arciero CA, Wang C, Broccoli D, Godwin AK. 2006. BRCC36 is essential for ionizing radiation-induced BRCA1 phosphorylation and nuclear foci formation...1999). BRCA1, BRCA2, and Rad51 operate in a common DNA damage response pathway. Cancer Res 59: 1752s- 1756s. Chen X, Arciero CA, Wang C, Broccoli D

  12. Design and Optimization of Copper Indium Gallium Selenide Solar Cells for Lightweight Battlefield Application

    DTIC Science & Technology

    2014-06-01

    those of the author and do not reflect the official policy or position of the Department of Defense or the U.S. Government. IRB Protocol number ____N...Matrix Flatpanel Displays and Devices, Kyoto , Japan, 2012, pp. 67–70. [23] R. Yang, Z. Bai, D. Wang, and D. Wang, “High efficient thin film CdTe solar

  13. Spectroscopy and Dynamics of Transient and Energetic Species

    DTIC Science & Technology

    2009-04-01

    Disc. 115, 161 (2000). C. C. Arnold and D. M. Neumark, J. Chem. Phys. 99 (5), 3353 (1993); G. F. Gantefor, D. M. Cox, and A. Kaldor , J. Chem. Phys. 96...125 (11) (2006). X. B. Wang, J. B. Nicholas , and L. S. Wang, J. Chem. Phys. 113 (24), 10837 (2000). M. F. Bush, R. J. Saykally, and E. R. Williams

  14. Development of a Strategy for Simulating Blast-Vehicle Interactions

    DTIC Science & Technology

    2010-09-01

    971, Livermore Software Technology Corporation , May 2007. [Lu and Wang, 2006] Lu, Y. and Wang, Z. (2006). Characterization of structural effects from...Robert (Chief, Geosciences and Structures Division) (2008) – private comunication , ERDC, Vicksburg, MS. [Wu et al., 2004] Wu, C., Hao, H., Lu, Y

  15. Best-First Heuristic Search for Multicore Machines

    DTIC Science & Technology

    2010-01-01

    w factor of the optimal solution cost) (Davis, Bramanti -Gregor, & Wang, 1988). It is possible to modify AHDA*, BFPSDD, and PBNF to use weights to... Bramanti -Gregor, A., & Wang, J. (1988). The advantages of using depth and breadth components in heuristic search. In Methodologies for Intelligent Systems 3

  16. Faculty Attitudes toward General Education Assessment: A Qualitative Study about Their Motivation

    ERIC Educational Resources Information Center

    MacDonald, Sarah K.; Williams, Laura M.; Lazowski, Rory A.; Horst, S. Jeanne; Barron, Kenneth E.

    2014-01-01

    As assessment becomes an ever more critical facet of higher education, it is apparent that some faculty do not always value assessment (Crossley & Wang, 2010; Ebersole, 2009). Further, faculty may react with resistance, particularly when they perceive that assessment is being imposed upon them from external sources (Crossley & Wang, 2010;…

  17. Metabolic Regulation of Caspase 2 in Breast Cancer

    DTIC Science & Technology

    2009-04-01

    Kurokawa, Yongjun Wang, Seth S. Margolis, Rafael A. Fissore, and Sally Kornbluth Scheduled for publication in Developmental Cell in June, 2009...Manabu Kurokawa1, Yongjun Wang4, Seth S. Margolis1, Rafael A. Fissore3, and Sally Kornbluth1 1Department of Pharmacology and Cancer Biology, Duke

  18. The Instruments of Power: A Computer-Assisted Game for the ACSC Curriculum

    DTIC Science & Technology

    2005-04-01

    Tolbert, Brian G. "Instruments of Power Game and Rules Development." Air Command and Staff College, 2005. Wang, Wallace. Visual Basic 6 for Dummies . New...Wang, Visual Basic 6 for Dummies (New York, NY: Wiley Publishing, 1998), 56-58. 56 Hasbro, Risk Rules (Pawtucket, RI: 1999). 57 Hasbro, Risk II Game

  19. Identification of miRNA Signatures Associated with Epithelial Ovarian Cancer Chemoresistance with Further Biological and Functional Validation of Identified Key miRNAs

    DTIC Science & Technology

    2015-02-01

    478-486. 7. Kumar S, Kumar A, Shah PP, Rai SN, Panguluri SK, Kakar SS. MicroRNA Signature of Cisplatin Resistant vs. Cis-Platin Sensitive Ovarian...Cancer Cell Lines. J Ovarian Res. 2011 Sep 22;4(1):17. 8. Yang L, Li N, Wang H, Jia X, Wang X, Luo J. Altered microRNA expression in cisplatin - resistant

  20. New Materials Design

    DTIC Science & Technology

    2007-11-02

    1653. 19. Wang, Z., Lupo , J., Patnaik, S., and Pachter, R.: Computational and Theoretical Polymer Science, 11(2001), 375. 20. Greengard, L., and...Rokhlin, V.: I. Comp. Phys., 73 (1987) 325.. 21. Wang, Z., Lupo , J.A., McKenney, A., and Pachter, R.: Proceedings of SC99 (1999), November 13-19, 1999, Portland, OR.

  1. Journal of the Chinese Silicate Society (Selected Articles).

    DTIC Science & Technology

    2014-09-26

    Diameter Sapphire Crystals in Tubular and Rod Shapes;, by Zhang Shouqing, Tang Lianan, Wang Wen, and Le Xiuhong ................................ 1...Jingwen....... ......................................... 21 ’< .. .L7- THE EFG GROWTH AND APPLICATION OF SMALL DIAMETER SAPPHIRE CRYSTALS • LIN TUBULAR AND...ROD SHAPES Zhang Shouqing, Tang Lianan, Wang Wen, Le Xiuhong (Shanghai Institute of Ceramics, Academia Sinica) Small diameter sapphire crystals in

  2. Factions in Communist China -- Around the Leadership of Mao.

    DTIC Science & Technology

    1960-07-11

    party organization led to confusion in the movement and simplified the way for Nationalist ; -,.-■- suppression. The Sze- chuan Autumn Harvest Rebellion...faction), Ch’iu-pai by the Nationalists, Li li-san by rtMlfuH and Wang-ming and Hsiang Ting by a battlewound. Only Wang-ming and Chang Kuo-shu were

  3. Protection Without Detection: A Threat Mitigation Technique

    DTIC Science & Technology

    2012-04-23

    international conference on Advances in Machine Learning and Cybernetics (ICMLC󈧉), Daniel S. Yeung, Zhi - Qiang Liu, Xi-Zhao Wang , and Hong Yan (Eds...Junchang Wang , Haipeng Cheng, Bei Hua, and Xinan Tang. 2009. Practice of parallelizing network applications on multi-core architectures. In Proceedings

  4. 78 FR 20106 - Ocean Transportation Intermediary License Applicants

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-03

    .... Officers: Cheng Lu, CFO (QI), Sherry Wang, President, Application Type: QI Change. Equinox Global..., Walnut, CA 91789. Officers: Philip Fut Chung Yuen (a.k.a. Philip) Yuen, COO (QI), Xiaojun Wang, President... 60106. Officer: Keh J. Wu, President (QI). Application Type: Add Trade Name, KCW-Logistics....

  5. A general Kastler-Kalau-Walze type theorem for manifolds with boundary

    NASA Astrophysics Data System (ADS)

    Wang, Jian; Wang, Yong

    2016-11-01

    In this paper, we establish a general Kastler-Kalau-Walze type theorem for any dimensional manifolds with boundary which generalizes the results in [Y. Wang, Lower-dimensional volumes and Kastler-Kalau-Walze type theorem for manifolds with boundary, Commun. Theor. Phys. 54 (2010) 38-42]. This solves a problem of the referee of [J. Wang and Y. Wang, A Kastler-Kalau-Walze type theorem for five-dimensional manifolds with boundary, Int. J. Geom. Meth. Mod. Phys. 12(5) (2015), Article ID: 1550064, 34 pp.], which is a general expression of the lower dimensional volumes in terms of the geometric data on the manifold.

  6. A review of Cyclidiinae from China (Lepidoptera, Drepanidae)

    PubMed Central

    Jiang, Nan; Liu, Shuxian; Xue, Dayong; Han, Hongxiang

    2016-01-01

    Abstract The subfamily Cyclidiinae from China is reviewed: two genera and seven species are reported from China. One new subspecies, Cyclidia fractifasciata indistincta subsp. n., is described. Two new synonyms are established: Cyclidia substigmaria (Hübner, 1831) (= Cyclidia substigmaria brunna Chu & Wang, 1987, syn. n. = Cyclidia tetraspota Chu & Wang, 1987, syn. n.). One misidentification in Chu & Wang (1987) is corrected. Identification keys and diagnoses for all discussed Chinese species are provided. External features and genitalia are depicted. In addition, results of DNA barcoding for five taxa of Cyclidia are briefly discussed. PMID:26877675

  7. Learning for Semantic Parsing and Natural Language Generation Using Statistical Machine Translation Techniques

    DTIC Science & Technology

    2007-08-01

    quite robust to input noise. Wang and Acero (2003) propose an extended HMMmodel for the ATIS do- main, where a multiple-word segment is generated from...tational Natural Language Learning (EMNLP-CoNLL-2007), pp. 22–32. Prague, Czech Republic. Ye-Yi Wang and Alex Acero (2003). Combination of CFG and n-gram...2809–2812. Geneva, Switzerland. Ye-Yi Wang, Li Deng and Alex Acero (2005). Spoken language understanding. IEEE Signal Processing Magazine, 22(5):16–31

  8. Accurate and Fast Localization of Prostate for External Beam Radiation Therapy

    DTIC Science & Technology

    2009-03-01

    reconstruction for CBCT using edge- preserving prior”, Medical Physics, vol. 36, pp. 252-260, 2009 3. L. Zhu, J. Wang, and L. Xing, “Noise suppression...1. J. Wang, A. Chai, L. Xing, “Noise correlation in CBCT projection data and its application for noise reduction in low-dose CBCT ”, poster...presentation in 2009 SPIE Medical Imaging conference, Orlando, FL 2. J. Wang, T. Li, and L. Xing, “Low-dose CBCT Imaging for External Beam Radiotherapy

  9. Development of Silica Fibers and Microstructures with Large and Thermodynamically Stable Second Order Nonlinearity

    DTIC Science & Technology

    2011-06-22

    C. Hofmann, Z. Liu, A. Wang, J. R. Heflin , and Y. Xu, “Demonstration of a cylindrically symmetric second-order nonlinear fiber with self-assembled...organic surface layers,” Opt. Express, 19 (11), 10326-10335 (2011). Y. Xu, M. Han, A. Wang, Z. Liu, and J. R. Heflin , “Second order parametric...processes in nonlinear silica microspheres,” Phys. Rev. Lett., 100, Art#163905, (2008). Y. Xu, A. Wang, J. R. Heflin , and Z. Liu, “Proposal and

  10. Direct Injection of Seawater for the Analysis of Nitroaromatic Explosives and their Degradation Products by Micellar Electrokinetic Chromatography

    DTIC Science & Technology

    2010-01-01

    Anal. Chem. 79 (2007) 6287. [9] J. Palmer, N.J. Munro, J.P. Landers, Anal. Chem. 71 (1999) 1679. [10] M. Pumera , J. Wang, E. Grushka, O. Lev, Talanta...72 (2007) 711. [11] X. Yao, J. Wang, L.Y. Zhang, P.Y. Yang, G. Chen, Talanta 69 (2006) 1285. [12] J. Wang, M. Pumera , Talanta 69 (2006) 984. [13] M... Pumera , Electrophoresis 27 (2006) 244. [14] M. Pumera , Electrophoresis 29 (2008) 269. [15] T. Hirokawa, T. Ichihara, K. Ito, A.R. Timerbaev

  11. Hybrid protocol of remote implementations of quantum operations

    SciTech Connect

    Zhao Ningbo; Wang Anmin

    2007-12-15

    We propose a protocol of remote implementations of quantum operations by hybridizing bidirectional quantum-state teleportation (BQST) [Huelga et al., Phys. Rev. A 63, 042303 (2001)] and the Wang protocol [Wang, Phys. Rev. A 74, 032317 (2006)]. The protocol is available for remote implementations of quantum operations in the restricted sets specified in the paper. We also give a proof of the protocol and point out its optimization. As an extension, this hybrid protocol can be reduced to the BQST and Wang protocols.

  12. Hormonal Resistance and Metastasis: ER-coregulator-Src Signaling Targeted Therapy

    DTIC Science & Technology

    2010-09-01

    Bindu Santhamma1, Binoj C. Nair1, Long Wang , Abhik Bandyopadhyay1, Joseph K. Agyin1, Darrell Brann2, Lu- Zhe Sun1, I-Tien Yeh1, Francis Y. Lee3...Biol. 118:211-218, 2010 3. Chakravarty D, Nair SS, Santhanama B, Nair BC, Wang L, Bandyopadhyay A, Agyin JA, Brann D, Sun L, Yeh I, Lee FY...62(3):162-9. 5. Chakravarty D, Nair S, Nair BC, Wang L, Bandyopadhyay A, Agyin JK, Lee F, Sun L, Yeh I, Tekmal RR, Vadlamudi RK. Therapeutic

  13. Beta 2-Microglobulin: A Novel Therapeutic Target for the Treatment of Human Prostate Cancer Bone Metastasis

    DTIC Science & Technology

    2009-03-14

    Odero-Marah V, Lue HW, Nomura T, Wang R, Chu G, Huang WC, and Chung LWK. (2008). Epithelial to Mesenchymal Transition (EMT) in Human Prostate...Cancer: Lessons Learned from ARCaP Model. Clinical and Experimental Metastasis. 25 (6):601-10, 2008. 4. Odero-Marah V, Wang R, Chu G, Xu J, Shi C...6198-206. 3. Zhau HE, Odero-Marah V, Lue HW, Nomura T, Wang R, Chu G, Huang WC, and Chung LWK. (2008). Epithelial to Mesenchymal Transition (EMT

  14. Descriptions of three new carbonaria-group species of Fannia Robineau-Desvoidy from China, with a key to the carbonaria-group species (Diptera, Fanniidae)

    PubMed Central

    Wang, Ming-fu; Li, Wei; Zhao, Yu-wan; Wu, Jie; Zhang, Dong

    2017-01-01

    Abstract A historical review of the Fannia carbonaria-group is provided and three new species are described from China: Fannia fani Wang & Wu, sp. n., Fannia nitidiventris Wang & Zhang, sp. n. and Fannia submaculata Wang & Zhao, sp. n.. One species, Fannia norvegica Ringdahl, 1934, is recorded for the first time from China. Illustrations of male terminalia of these four species and a taxonomic key to the males of known species in the group are given. The Fannia carbonaria-group now includes 30 species distributed in the Holarctic Region and northern part of the Oriental Region. PMID:28331411

  15. Three new species of Baeoentedon Girault (Hymenoptera: Eulophidae) from China, with the first record of whitefly host association (Hemiptera: Aleyrodidae).

    PubMed

    Wang, Zhu-Hong; Huang, Jian; Polaszek, Andrew

    2014-07-01

    Three new species of Baeoentedon Girault (Hymenoptera: Eulophidae) are described from China, Baeoentedon balios Wang, Huang & Polaszek sp. nov., Baeoentedon bouceki Wang, Huang & Polaszek sp. nov. and Baeoentedon virgatus Wang, Huang & Polaszek sp. nov. Both female and male of Baeoentedon balios were reared from the whitefly Pealius spina (Singh) (Hemiptera: Aleyrodidae) on the bodhi tree Ficus religiosa L. (Urticales: Moraceae). The male and the whitefly host association of Baeoentedon are recorded for the first time. A key is also provided to females of the world species of the genus.

  16. Room-Temperature Photocurrent Spectroscopy of GaAs/GaAlAs Multiple Quantum Wells,

    DTIC Science & Technology

    1994-11-15

    Hailong , Wang Qiuning, et al. DO..... ... . .I C- DTIC ~ELECTIEE 199|11O9034 19950109 034Ditiuinnlmed NAIC- ID(RS)T-0385-94 AOSSI.O •z [ A Si8 eol1Y de...MULTIPLE QUANTUM WELLS 5y: Duan Hailong , Wang Qiuning, et al. English pages: 12 Source: Bandaoti Xuebao, Vol. 12, Nr. 7, July 1991, pp. 399-4O4...TEMPERATURE PHOTOCURRENT SPECTROSCOPY OF GaAs/GaAlAs MULTIPLE QUANTUM WELLS DUAN HAILONG , WANG QIUNING, WU RONGHAN, ZENG YIPING and KONG MEIYING

  17. Overview of High-Temperature Superconductivity: Theory, Surfaces, Interfaces and Bulk Systems

    DTIC Science & Technology

    1988-06-01

    superconductivity. The RVB theory has been amplified or modified in several ways [5,6,7], the details of which we won’t go into here. Rice and Wang [8] have...similar to those of RVB theory, but different from BCS theory. Rice and Wang , however, favor a phonon interaction which mediates the attraction between...36, 857. 7. Kotliar, G. Phys. Rev. B,1988, IZ, 3664. 8. Rice, M. J.; Wang , Y. R. Phys. Rev.-B, 1988, 37, 5893. 9. Coffey, L.; Cox, D. L. Phys. Rev

  18. Managing Computer Systems Development: Understanding the Human and Technological Imperatives.

    DTIC Science & Technology

    1985-06-01

    VENDOR ENVIRONNEIT TYPE Salvo Several 8- 16-bit DBMS, 4GL Software Automation CP/N, CP/M-86, 14333 Proton Rd. MS-DOS Dallas, TI 75238 Speed II Wang ...VS, Wang 2200 Query, 4GL The office manager 127 SW 156th St. P.O. Box 66596 Seattle, WA 98166 System I IBM 370/4300/301X A Decision Conshare KVS/TSO...DEC VI# Unix, 15530 Rockfield Blvd. IBM-PC Irvine, CA 92714 Focus IBM 370/4300/30XX DBMS, Query, Information Builders DOS, VM, MVS, Wang , 4GL 1250

  19. Compact Broad-Band Wavelength-Agile Mid-Infrared Semiconductor Lasers for Spectroscopic Sensing

    DTIC Science & Technology

    2004-12-01

    IEEE Photon. Technol. Lett. Jan 2005). Yi Wang, Chuan Peng, HuanLin Zhang, and Han Q. Le, “Wavelength modulation imaging with tunable mid- infrared...Wen-Yen Hwang, Jae Um, Bujin Guo, Hao Lee, and Chih- Hsiang Lin, “Continuous-wave operation of a 5.2 µm quantum-cascade laser up to 210 K”, Appl. Phys...Lett. 79, 1745-1747, (2001). 2. Proceedings Yi Wang, Yang Wang, Chuan Peng, HuanLin Zhang, Anush Seetheraman, and Han Q. Le, “Concepts for Scalable

  20. Testicular Microlithiasis: Is It Associated with Testicular Cancer?

    MedlinePlus

    ... cell tumors (FTGCT) — Overview of a multidisciplinary etiologic study. Andrology. 2015;3:47. Pedersen MR, et al. Testicular microlithiasis and testicular cancer: Review of the literature. International Urology and Nephrology. 2016;48:1079. Wang T, ...

  1. A new species of Coccus (Hemiptera, Coccoidea, Coccidae) from China

    PubMed Central

    Wang, Fang; Feng, Ji-Nian

    2012-01-01

    Abstract A new species of soft scale, Coccus multisetus Wang & Feng, sp. n. is described and illustrated from Yunnan, China. A key to adult females of all Coccusknown from China is provided. PMID:23275744

  2. Optimal Inventory Policy for Two-echelon Remanufacturing

    DTIC Science & Technology

    2007-04-30

    with remanufacturing and procurement leadtimes. Magdeburg, Germany: Faculty of Economics and Management Otto -von- Guericke -University Magdeburg...of Economics and Management Otto - von- Guericke -University Magdeburg. Johnson, M. R., & Wang, M. H. (1995). Planning product disassembly for

  3. Heart pacemaker

    MedlinePlus

    ... PA: Elsevier Saunders; 2015:chap 37. Swerdlow CD, Wang PJ, Zipes DP. Pacemakers and implantable cardioverter-defibrillators. ... and lifestyle Controlling your high blood pressure Dietary fats explained Fast food tips Heart attack - discharge Heart ...

  4. Implantable cardioverter-defibrillator

    MedlinePlus

    ... ncbi.nlm.nih.gov/pubmed/23265327 . Swerdlow CD, Wang PJ, Zipes DP. Pacemakers and implantable cardioverter-defibrillators. ... and lifestyle Controlling your high blood pressure Dietary fats explained Fast food tips Heart attack - discharge Heart ...

  5. Corrigendum to "Groundwater storage changes in the Tibetan Plateau and adjacent areas revealed from GRACE satellite gravity data" [Earth Planet. Sci. Lett. 449 (2016) 228-239

    NASA Astrophysics Data System (ADS)

    Xiang, L.; Wang, H.; Steffen, H.; Wu, P.; Jia, L.; Jiang, L.; Shen, Q.

    2016-10-01

    The authors regret that the Acknowledgement was published with the funding support for Hansheng Wang declared in the incorrect order. The corrected Acknowledgement is as follows (please note the revised section appears in italics):

  6. Urinary Incontinence

    MedlinePlus

    ... urinary incontinence. Initial pilot studies have shown that acupuncture can provide some short-term benefit, but more ... Urology. 2013;190:113. Wang Y, et al. Acupuncture for stress urinary incontinence in adults. Cochrane Database ...

  7. Commonly Prescribed Blood Thinner Associated with Higher Risk of Post-Surgery Complications

    MedlinePlus

    ... are crucial steps," concluded first author Zhong Wang, Ph.D., also of NIAMS. "Clinicians should consider all factors when choosing which type of blood clot prevention strategy to prescribe for their patients." ...

  8. Development of Nanostructured Metallic Systems-Progress and Challenges

    DTIC Science & Technology

    2003-09-01

    Larsen - GEGR, Niskayuna • Michelle Othon - GEGR, Niskayuna • Ann Ritter - GEGR, Niskayuna • Chris Furstoss - GEGR, Niskayuna • Yunzhi Wang - Ohio State University • Hamish Fraser - Ohio State University

  9. 75 FR 75173 - Change in Bank Control Notices; Acquisitions of Shares of a Bank or Bank Holding Company

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-02

    ..., Villanova, Pennsylvania; Tony Yi Ping Wang and Michelle Yichun Yang, Gladwyne, Pennsylvania; Elliot Hong Wai... Corporation, and thereby indirectly acquire voting shares of Asian Bank, both of Philadelphia, Pennsylvania....

  10. Aortic valve surgery - minimally invasive

    MedlinePlus

    ... of the heart is reduced. This is called aortic stenosis. The aortic valve can be replaced using: Minimally ... RN, Wang A. Percutaneous heart valve replacement for aortic stenosis: state of the evidence. Ann Intern Med . 2010; ...

  11. Curve Fitting and First Quadrant Plotting Program (CURVPLOT).

    DTIC Science & Technology

    designed to be used on the Wang 720B Electronic Programmable Calculator and 702 Plotting Output Writer combination. The regular plotter typing element is replaced with an IBM Dual Gothic typing element. (Author)

  12. Reply to 'Comment II on 'Quantum secret sharing based on reusable Greenberger-Horne-Zeilinger states as secure carriers''

    SciTech Connect

    Karimipour, V.

    2006-07-15

    In the preceding Comment [Jian-Zhong Du, Su-Juan Qin, Qiao-Yan Wen, and Fu-Chen Zhu, Phys. Rev. A 74, 016301 (2006)], it has been shown that in a quantum secret sharing protocol proposed in [S. Bagherinezhad and V. Karimipour, Phys. Rev. A 67, 044302 (2003)], one of the receivers can cheat by splitting the entanglement of the carrier and intercepting the secret, without being detected. In this reply we show that a simple modification of the protocol prevents the receivers from this kind of cheating.

  13. Molecular Basis of Genomic Instability in Breast Cancer: Regulation of the Centrosome Duplication Cycle

    DTIC Science & Technology

    2005-06-01

    NUMBER DAMD17-02-1-0344 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Jian Du, Ph.D. 5d. PROJECT NUMBER Gregory Hannon, Ph.D. 5e. TASK NUMBER...annual report 2004) We completed the proposal task 1 to 5 in the study. During the time periods of the project , we modified the course of the...proposal design and experiments according to the project progression and time frame (see the annual report 2003 and 2004). Although I worked on the

  14. Microsphere Composites of Nano-Al and Nanothermite: An Approach to Better Utilization of Nanomaterials

    DTIC Science & Technology

    2014-01-01

    34 Journal of Materials Chemistry, Vol. 21, No. 26, 2011, pp. 9400-9405. 6Jian, G. Q., Liu L., and Zachariah, R. M., "Facile Aerosol Route to Hollow CuO...1341–1346. 7Ali, A. N., Son, S. F., Hiskey, M. A., and Naud, D. L., "Novel high nitrogen propellant use in solid fuel micropropulsion," Journal of...Composites (Al/MoO3, Al/WO3, Al/CuO, and B12O3),” Journal of Propulsion and Power, Vol. 23, No. 4, July.-Aug. 2007, pp. 707-714. 11Ilyushin, M. A

  15. Instability of the vertically forced surface wave in a circular cylindrical container

    NASA Astrophysics Data System (ADS)

    Jian, Yong-Jun; E, Xue-Quan

    2004-10-01

    The nonlinear amplitude equation, which was derived by Jian Yongjun employing expansion of two-time scales in inviscid fluids in a vertically oscillating circular cylindrical vessel, is modified by introducing a damping term due to the viscous dissipation of this system. Instability of the surface wave is analysed and properties of the solutions of the modified equation are determined together with phase-plane trajectories. A necessary condition of forming a stable surface wave is obtained and unstable regions are illustrated. Research results show that the stable pattern of surface wave will not lose its stability to an infinitesimal disturbance.

  16. Applications of Low-Coordination Phosphorus Chemistry in the Chemical Modification of Surfaces

    DTIC Science & Technology

    1992-11-13

    Diels - Alder adduct 39 as a mixture of two positional isomers, each as two configurational isomers. The mixture is used as such for the reduction step...Quin, Jian-Sheng Tang, and Gyorgy Keglevich, " Diels - Alder Adducts of 4-Chloro-1,6- Dihydrophosphinine Derivatives: A New Precursor of 2-Phosphapropene...Management and 8,lget. Paperwoek Red.cto" Projel (07 04-0181) Wairngion. DC 20503 1. AGENCY USE ONLY (Leave blank) 12. REPORT DATE I3. REPORT TYPE AND

  17. Exploring Novel Forms of Superconductivity

    DTIC Science & Technology

    2012-10-19

    REPORT FINALPROJECT REPORT: W911NF-08-1-0196 “EXPLORING NOVEL FORMS OF SUPERCONDUCTIVITY ....” 14. ABSTRACT 16. SECURITY CLASSIFICATION OF: Novel...Rev 8/98) Prescribed by ANSI Std. Z39.18 - 30-Jun-2011 FINALPROJECT REPORT: W911NF-08-1-0196 “EXPLORING NOVEL FORMS OF SUPERCONDUCTIVITY ...publications (other than abstracts): Received Paper 12/24/2009 1.00 Jian Liu, M. Kareev, S. Prosandeev, B. Gray, P. Ryan, J.W. Freeland, J. Chakhalian. Effect

  18. [An investigation into the Jin xiao fang (Prescriptions of Instant Effect), a lost recipe book of the Tang Dynasty].

    PubMed

    Huang, Bin; Zhang, Yin-Zhu

    2013-07-01

    Altogether 141 prescriptions in the Jin xiao fang (Prescriptions of Instant Effect), a lost recipe book of the Tang Dynasty are cited in the Wai tai mi yao (Medical Secrets of An Official). Based on the analysis of these citations, it can be sure that the Jin xiao fang was written by Li Jian-yi of the Tang Dynasty, and completed around 724 to 733. These cited prescriptions are related to the clinical subjects, with complicate origins, for example, physicians and scholars. It is characterized by its "xiao yan (efficacy)".

  19. Toward Active Control of Noise from Hot Supersonic Jets

    DTIC Science & Technology

    2013-12-31

    control valves upstream of the nozzle through the use of a proportional-integral-derivative controller ( PID ) that allows to minimize the error by...adjusting the percentage of aperture of the tuning valve. The variability of the NPR over all the tests was found to be less "Jian 1%; Figure Ha shows the...36.7 : we first open the main valve to a value of 10%, and when ;he NPR gets high enough we open manually to 35% the tuning valve, and at t = 20s we

  20. Probing into the Secret of the Chinese Air Force.

    DTIC Science & Technology

    1983-11-30

    Equipment of China’s Aviation Units Several Fighters Made by China - the Jian-6, Qiang -5, Hong-5 54 and Hong-6 China’s Yun-llT Multipurpose Aircraft 79...The Successful Development of China’s Yun-7 Medium Short 89 Range Transport. China’s Qiang -5 Attack Aircraft 99 Front Cover: China’s Qiang -5 Attack...scale growth in products for civilian use. 2 " ’ -. ..- .. . .. .". . ’- . ; i Fig. 1 Newly built - Qiang -5 attack aircraft. 3 -- A ..- t 4

  1. Handbook of Equipment Repair.

    DTIC Science & Technology

    1981-05-14

    canital asic side-bown Gr-Ide I steel conwerter Jian J Grade 3 steel B Top-,!own Special kind converter Ding V D steel C 3oilin- steel ""u R ivet screw 1...de, bol>’ or screw, ’ot-Dress ie and hot-snear-.nc u r 1𔃽L -,r’~n Die block, scr rin-out cu-,ter, measZ-,r4i -,e and die1*- o’ I com-Pli czt ed

  2. China Report, Political, Sociological and Military Affairs

    DTIC Science & Technology

    2007-11-02

    difficulties that may arise from this trend, an article in the Gongren RIBAO (Workers’ DAILY) newspaper suggests : —Introducing labour-saving techniques and...indicates inadequate musical education in primary and middle schools, he stresses. Lin suggests that artistic colleges should train more primary and...security, judicial, and procuratorial front. Over 900 persons were commended. Wang Senhao, governor of Shanxi, and Wang Jiangong, deputy secretary of the

  3. Development of Personalized Cancer Therapy for Men with Advanced Prostate Cancer

    DTIC Science & Technology

    2015-10-01

    Representative sagittal MR images of femurs. Images were acquired using T2- weighted fast spin echo sequence with fat suppression of femurs bearing MDA PCa 118b...Nearest person month worked: 3 calendar months Contribution to Project: Ms. Wang is responsible for preparing cell and tumor lines for the planned...therapies in the mouse model and in paired patient biopsy samples. Prime: PR110555 ( Wang ); CPRIT Subaward: S110092 Title: Activation of Prostate

  4. Leucine Modulation of the mTOR Pathway for Cognition Modulation: Kinetic and In Vitro Studies and Model Development

    DTIC Science & Technology

    2015-09-30

    Hall, 2008; Wang et al., 2008). mTOR complexes regulate many processes such as mRNA translation, autophagy, metabolism, biogenesis, and protein...amino acids, especially leucine (Lynch et al., 2003; Sancak and Sabatini, 2009; Tokunaga et al., 2004; Wang et al., 2008). Hypothalamic mTOR...blood, brain, kidney, liver, muscle, and brown and white fat (n=3 rats per time point). The tissues were kept frozen at -80°C prior to HPLC analysis

  5. Development of Personalized Cancer Therapy for Men with Advanced Prostate Cancer

    DTIC Science & Technology

    2015-10-01

    sequence with fat suppression of femurs bearing MDA PCa 118b derived tumors in control and treated mice. Arrows indicate tumor. (B) Tumor volume...person month worked: 3 calendar months Contribution to Project: Ms. Wang is responsible for preparing cell and tumor lines for the planned experiments...therapies in the mouse model and in paired patient biopsy samples. Prime: PR110555 ( Wang ); CPRIT Subaward: S110092 Title: Activation of Prostate

  6. Genetic Variations in Mitochondria and Prostate Cancer Aggressiveness and Progression in Caucasian and African American Men

    DTIC Science & Technology

    2015-09-01

    levels has been explored in a few studies [68, 69]. Consistent with our findings, Lee et al found that visceral fat area was independently inversely...PubMed PMID: 19647296. 14. Wang L, McDonnell SK, Hebbring SJ, Cunningham JM, St Sauver J, Cerhan JR, et al. Polymorphisms in mitochondrial genes and...PubMed Central PMCID: PMC3916805. 21. Cui H, Huang P, Wang Z, Zhang Y, Zhang Z, Xu W, et al. Association of decreased mitochondrial DNA content

  7. Developing Wide-Spectrum Antiproteotoxicity Agents to Treat ALS

    DTIC Science & Technology

    2013-10-01

    phenotypes in C. elegans and mouse models of ALS. Progress Report Wang, Jiou 5 Overview: In this Aim, we hypothesize that increased HSF -1...2009a; Wang et al., 2009b). In a related finding, a reduction in HSF -1 activity dramatically precipitated neuronal toxicity in TDP-43 transgenic C...Fiesel et al., 2010; Sephton et al., 2010; Wu et al., 2010). Previously, we made an observation of genetic interaction between TDP-43 and HSF -1

  8. On Robust Control Designs for Infinite Dimensional Systems

    DTIC Science & Technology

    1986-09-01

    1975. 41. Gallier, F.M. and C.A. Desoer . "An Algebra of Transfer Functions for Distributed Linear Time-Invariant Systems." IEEE Trans, on Circuits and...equality known to date, and Desoer and Wang’s generalized Nyquist theorem [24] to establish that for linear systems described as a semigroup over a...obtained by formalizing the concepts behind the Yakubovich frequency domain theorem and the Desoer and Wang generalized Nyquist theorem. The

  9. Review of the genus Harnischia Kieffer from China (Diptera, Chironomidae), with description of one new species

    PubMed Central

    Yan, Chun-Cai; Guo, Qin; Liu, Ting; Guo, Wei; Wang, Xin-Hua; Pan, Bao-Ping

    2016-01-01

    Abstract The genus Harnischia Kieffer, 1921 from China is reviewed and one new species, Harnischia parallela Yan & Wang, sp. n., is described and illustrated as adult male. Harnischia okilurida Sasa is recognized as a new synonym of Harnischia longispuria Wang & Zheng. The pupae of Harnischia fuscimana Kieffer and Harnischia curtilamellata Malloch are redescribed from material collected in China, and an unplaced pupa is described. Key to male adults and pupae of known species of Harnischia from China is given. PMID:27917051

  10. Efficient Extraction of Drainage Networks from Massive, Radar-Based Elevation Models with Least Cost Path Search

    DTIC Science & Technology

    2011-02-25

    Planchon and Darboux, 2001; Wang and Liu, 2006). Improved sink filling methods (e.g. Garbrecht and Martz, 1997; Grimaldi et al., 2007; Santini et al...by sink filling, efforts have been made to add a gradient to these flat areas (e.g. Martz and Garbrecht, 1998; Wang and Liu, 2006; Grimaldi et al...Foundation, http://grass.osgeo.org, 2010. Grimaldi , S., Nardi, F., Di Benedotto, F., Istanbulluoglu, E., and Bras, R. L.: A physically-based method for

  11. Supervisory Control of Unmanned Vehicles

    DTIC Science & Technology

    2010-04-01

    prone automation, (e.g., the “cry wolf ” effect) and hurt performance (both speed and accuracy) at least as much as MP automation on the concurrent...Wang and Lewis, 2006; Wang et al., 2009) and other exploration and reconnaissance tasks (Trouvain et al., 2003; Trouvain and Wolf , 2002). Olsen and... Wolf (2002), participants used either two, four, or eight simulated UGVs to perform inspection tasks at the predesignated inspection locations

  12. The Risk and Clinical/Molecular Characteristics of Breast Cancer in Women with Neurofibromatosis Type 1

    DTIC Science & Technology

    2012-10-01

    Characteristics of Breast Cancer in Women with Neurofibromatosis Type 1 PRINCIPAL INVESTIGATOR: Xia Wang, M.D., Ph.D...Women with Neurofibromatosis Type 1” 5a. CONTRACT NUMBER 5b. GRANT NUMBER W81XWH-11-1-0671 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Xia Wang...Several reports from England and the United States have described increased breast cancer occurrence in women affected with Neurofibromatosis type 1

  13. Next Generation Energetic Materials: New Cluster Hydrides and Metastable Alloys of Aluminum in Very Low Oxidation States

    DTIC Science & Technology

    2016-10-01

    carbon = dark gray, lithium = purple, nitrogen = dark blue, oxygen = red, silicon = light gray, sodium = yellow. Recently, we also have obtained the...Soc., 136, 3607–3616 (2014) 9. "Aluminum Zintl Anion Moieties within Sodium Aluminum Clusters", H. Wang, X. Zhang, J. Ko, A. Grubisic, X. Li, G...Zintl anion moieties within sodium aluminum clusters Haopeng Wang,1 Xinxing Zhang,1 Yeon Jae Ko,1 Andrej Grubisic,1 Xiang Li,1 Gerd Ganteför,1

  14. A Review and Assessment of Current Airframe Lifing Methodologies and Tools in Air Vehicles Division

    DTIC Science & Technology

    2006-12-01

    under strain - controlled test, demonstrating the gradual relaxation of mean stress (Hu and Wang 2000) ....................... 20 Figure 7 Schematic of...are typically generated by conducting a series of strain - controlled experiments on smooth specimens subjected to fully reversed constant amplitude...specimens subjected to strain - controlled loading (Hu and Wang 2000), where the numerical results were obtained using a non-linear kinematic hardening

  15. A Bayesian Analysis of Scale-Invariant Processes

    DTIC Science & Technology

    2012-01-01

    Analysis of Scale-Invariant Processes Jingfeng Wang, Rafael L. Bras, Veronica Nieves Georgia Tech Research Corporation Office of Sponsored Programs...processes Veronica Nieves , Jingfeng Wang, and Rafael L. Bras Citation: AIP Conf. Proc. 1443, 56 (2012); doi: 10.1063/1.3703620 View online: http...http://proceedings.aip.org/about/rights_permissions A Bayesian Analysis of Scale-Invariant Processes Veronica Nieves ∗, Jingfeng Wang† and Rafael L. Bras

  16. JPRS Report, Science & Technology, China

    DTIC Science & Technology

    2007-11-02

    CHINA CONTENTS LASERS, SENSORS, OPTICS Reports on Pulsed Power Research 1 High-Voltage Steep-Pulse Generator [Wang Xiaojun, Chen Ping, et al...XUEKAN, Mar 92]. ൝ - a - LASERS, SENSORS, OPTICS Reports on Pulsed Power Research High-Voltage Steep-Pulse Generator 92FE0732A Chengdu QIANG...JIGUANG Yü LIZI SHU [HIGH POWER LASER AND PARTICLE BEAMS] in Chinese Vol 4 No 2, May 92 pp 228-232 [Article by Wang Xiaojun [3769 0879 6511], Chen Ping

  17. Endoplasmic Reticulum-Associated Degradation Factor ERLIN2: Oncogenic Roles and Molecular Targeting of Breast Cancer

    DTIC Science & Technology

    2013-06-01

    fatty acid synthesis and expression of lipogenic genes in breast c © The Authors Journal compilation c © 2012 Biochemical Society 22 ERLIN2 regulates lipid...differentiated functions in chemically defined medium. Cancer Res. 42 , 3858–3863 20 Laing, S., Wang, G., Briazova, T., Zhang, C ., Wang, A., Zheng, Z... C ) Expression of the ERLIN2 gene and the genes involved in lipid droplet formation and lipogenesis, including FSP27, ADRP and FIT1, in ERLIN2

  18. Plasmonic Graphene Transparent Conductors

    DTIC Science & Technology

    2012-01-01

    www.MaterialsViews.com www.advopticalmat.de FU LL P A P ER Guowei Xu,* Jianwei Liu, Qian Wang, Rongqing Hui, Zhijun Chen, Victor A. Maroni , and Judy Wu Plasmonic...Wang, Rongqing Hui, Zhijun Chen, Victor A. Maroni , Judy Wu University of Kansas Center for Research, Inc. 2385 Irving Hill Road Lawrence, KS 66045...A. Maroni Materials Science Division, Bldg 212 Argonne National Laboratory Argonne, IL 60439, USA DOI: 10.1002/adma.201104846 1. Introduction

  19. The Impact of Changes in State Identity on Alliance Cohesion in Northeast Asia

    DTIC Science & Technology

    2009-12-01

    School, Sun Zhe at Tsinghua University, and Zhan Debin at Fudan University, began to publicly express their new perceptions of the capabilities...Rin 4 al Hong Xuezhi 1 henyang MRC Wang Ke General Kim Hak Sam 994 DDM Kim Jong Kak COGS Choe Kwang General Oh Yong Bang 5 S 1995 MDN DFAB Sun...Qixiang AMS PC Zhang Gong Guangzhou MRPC Shi Yuxia DDM Kim Jong Kak 4 1996 ILD Deputy Director Dai Bingguo North Sea FC Wang Jiying

  20. Hormonal Resistance and Metastasis: ER-coregulator-Src Targeted Therapy

    DTIC Science & Technology

    2009-09-01

    1. Dimple Chakravarty, Sujit Nair, Binoj Chandrasekhar Nair, Long Wang , Abhik Bandyopadhyay, Joseph K. Agyin, Frank Lee, Lu- Zhe Sun, I-Tien Yeh...Poster Board Number: 11 Author Block: Dimple Chakravarty, Sujit Nair, Binoj Chandrasekhar Nair, Long Wang , Abhik Bandyopadhyay, Joseph K. Agyin, Frank...Lee, Lu- Zhe Sun, I-Tien Yeh, Rajeshwar Rao Tekmal, Ratna K. Vadlamudi. UT Health Science Ctr., San Antonio, TX, Bristol-Myers Squibb Pharmaceutical

  1. Identification of Genes Regulating the Development of Breast Cancer

    DTIC Science & Technology

    2008-04-01

    Tumor Development Hua Wang, Douglas Teske , Alyssa Tess, Rebecca Kohlhepp, YounJeong Choi, Christina Kendziorski, and Amy Rapaich Moser Cancer Res...Tumor Development Hua Wang, 1,3 Douglas Teske , 1 Alyssa Tess, 1 Rebecca Kohlhepp, 1 YounJeong Choi, 2 Christina Kendziorski, 2 and Amy Rapaich Moser 1... Teske ), and palpable tumors were recorded when first noted and then confirmed at necropsy. The total tumor number was determined at necropsy by noting

  2. Relative Equilibria of a Rigid Satellite in a Central Gravitational Field

    DTIC Science & Technology

    1997-09-01

    thank the members of my committee, Dr. David Weeks, Dr. William Wiesel, and Dr. William Brown, for their valuable comments and suggestions. In...potential and in 1985 Barkin [9] showed the existence of oblique orbits by including third- order inertia integrals in the potential. In 1991, Wang...instance, Meirovitch [69] and Barkin [9]). Wang et al [104] were the first to address the topic of consistent approximations. They noted that the

  3. From Ultrafine Thiolate-Capped Copper Nanoclusters toward Copper Sulfide Nanodiscs: A Thermally-Activated Evolution Route

    DTIC Science & Technology

    2009-08-13

    Kim, K . T .; Jeong, Y. J .; Hong, S. H . 1. Mater. Res. 2006, 21 , 2371. (19) Wang, J. ; Huang, H. ; Kesapragada, S. V.; Gall , D . Nano. Lett...1183. ( 21 ) (a) Wang, T.; Yang, W. ; Wu, L. ; Chen, c.; Chu, C. Nanotechnology 2006, 17,7 19. (b) Kim, c.; Gu, W ; Briceno, M. ; Robertson, I. M.; Choi...104, 1206. Matt et al. deposition, 19,20 chemical vapor deposition, 21 y-irradiation,22 UV-light irradiation,23 and sonochemical methods. 24

  4. High Order Accurate Algorithms for Shocks, Rapidly Changing Solutions and Multiscale Problems

    DTIC Science & Technology

    2013-01-07

    Chi-Wang Shu. Point -wise hierarchical reconstruction for discontinuous Galerkin and finite volume methods for solving conservation laws, Journal of...Ishani Roy, Chi-Wang Shu, Li-Zhi Fang. EFFECT OF DUST ON Ly? PHOTON TRANSFER IN AN OPTICALLY THICK HALO, The Astrophysical Journal, (10 2011): 0. doi...continuous at the junction points where two quadratic polynomials meet, and with piecewise linear initial condition and piecewise constant boundary

  5. Adaptive Piezoelectric Circuitry Sensor Network with High-Frequency Harmonics Interrogation for Structural Damage Detection

    DTIC Science & Technology

    2014-09-17

    Harmonics Interrogation for Structural Damage Detection FA9550-11-1-0072 Kon-Well Wang and Jiong Tang The Regents of the University of Michigan, 3003...Well Wang 734-764-8464 1    Adaptive Piezoelectric Circuitry Sensor Network with High-Frequency Harmonics Interrogation for Structural Damage Detection...limitations. This research explores damage identification via advancing a third type of approach: high-frequency harmonic excitation-based self

  6. Modeling and Performance Evaluation of Backoff Misbehaving Nodes in CSMA/CA Networks

    DTIC Science & Technology

    2011-08-01

    Modeling and Performance Evaluation of Backoff Misbehaving Nodes in CSMA/CA Networks Zhuo Lu, Student Member, IEEE, Wenye Wang, Senior Member, IEEE...and Cliff Wang Abstract—Backoff misbehavior , in which a wireless node deliberately manipulates its backoff time, can induce significant network... misbehavior , little attention has been focused on quantifying the gain of backoff misbehaviors . In this paper, to assess the gain that misbehaving nodes can

  7. Carving out Their Own Niche

    ERIC Educational Resources Information Center

    Lum, Lydia

    2007-01-01

    Asian-American performers were few and far between when Dr. Oliver Wang was growing up in the 1970s and '80s. Looking back, Dr. Wang, an assistant professor in sociology at California State University-Long Beach, says the lack of artists may have been the result of a lack of role models, since Asian immigrants did not begin to arrive in the United…

  8. Functionality and Usability Assessment of the Complement Generation Tool (CGT): A Preliminary Review (Evaluation de la Fonctionnalite et de la Convivialite de Generation de Complements (CGT) - Examen Preliminaire)

    DTIC Science & Technology

    2011-04-01

    Functionality and Usability Assessment of the Complement Generation Tool (CGT) A preliminary review Wenbi Wang...Functionality and Usability Assessment of the Complement Generation Tool (CGT) A preliminary review Wenbi Wang Defence R&D...que représentée par le ministre de la Défense nationale, 2011 DRDC Toronto TM 2011-057 i Abstract …….. The Complement Generation Tool

  9. Metallic Material Image Segmentation by using 3D Grain Structure Consistency and Intra/Inter-Grain Model Information

    DTIC Science & Technology

    2015-01-05

    Cao, Q. Li, Q. Mao, and S. Wang. Cracktree: Automatic crack detection from pavement images . Pattern Recognition Letters, 33:227–238, 2012. 17 Personnel...Y. Cao, Q. Li, Q. Mao, S. Wang. CrackTree: Automatic Crack Detection from Pavement Images , Pattern Recognition Letters, 33(3):227-238, 2012 20 34. F...Superalloy Image Segmentation, IEEE Conference on Computer Vision and Pattern Recognition (CVPR), 17-24, Colorado Springs, CO, 2011 Dissertations: Four

  10. Multiscale Modeling and Computation of Liquid Crystal Polymers, Polymer Blends, and Polymer Nanocomposites: Investigation of Rheology and Material Properties

    DTIC Science & Technology

    2008-04-15

    Newtonian Fluid Mechanics, 2006, 128(1): 44-61. 4. M. G. Forest, R. Zhou, and Q. Wang, Nano-rod suspension flows: a 2D Smoluchowski- Navier - Stokes ...pp. 1-21. 23. M. G. Forest, R. Zhou, and Q. Wang, “Nano-rod suspension flows: a 2D Smoluchowski- Navier - Stokes solver”, International Journal of...principle. The probability density function is sought by a spectral method for the Smoluchowski equation based on the Wigner function expansion. Lower

  11. Advanced Nanostructures for Two-Phase Fluid and Thermal Transport

    DTIC Science & Technology

    2014-08-07

    AFRL-OSR-VA-TR-2014-0183 (YIP 11) Advanced Nanostructures for Two-Phase Fluid and Thermal Transport Evelyn Wang MASSACHUSETTS INSTITUTE OF TECHNOLOGY...Advanced Nanostructures for Two-Phase Fluid and Thermal Transport AFOSR Grant FA9550-11-1-0059 Final Report Evelyn N. Wang Associate Professor...heated channel wall. Small fluctuations in the measured heater surface temperature (± 3-8 °C) indicated increased flow stability, and the heat transfer

  12. On-board Model Predictive Control of a Quadrotor Helicopter: Design, Implementation, and Experiments

    DTIC Science & Technology

    2012-12-13

    and Boyd, 2010; Rao, Wright, and Rawlings , 1998). In a short coda, we describe experiments and simulations where a new primal-dual infeasible-start...prediction horizon of the QP-MPC (Wang and Boyd, 2010; Rao, Wright, and Rawlings , 1998), as opposed to non-sparse solvers that scale cubicly. Other...in contrast to the dense active set solvers whose computation times are well-known (Wang and Boyd, 2010; Rao, Wright, and Rawlings , 1998) to scale

  13. Concurrent EEG And NIRS Tomographic Imaging Based on Wearable Electro-Optodes

    DTIC Science & Technology

    2014-04-13

    2012.02.008 Y. M. Chi, Yu-Te Wang, Yijun Wang, C. Maier, Tzyy-Ping Jung, G. Cauwenberghs. Dry and Noncontact EEG Sensors for Mobile Brain–...oxyhemoglobin   ([HbO2])  and  deoxyhemoglobin   ([Hb])  when  external   force  was  applied   to   the   forearm   to

  14. Human Rights in China: Trends and Policy Implications

    DTIC Science & Technology

    2009-07-13

    the deaths and assistance for those injured or maimed. Former protest leaders living abroad have been denied entry into China. Zhou Yongjun , a...politically sensitive postings and other activities online.50 46 Hongying Wang and Xueyi...September 19, 2008. 48 Hongying Wang and Xueyi Chen, “Globalization and the Changing State-Media Relations in China,” op. cit.; Christopher Walker and

  15. Human Rights in China: Trends and Policy Implications

    DTIC Science & Technology

    2009-06-12

    into China. Zhou Yongjun , a Beijing student leader in 1989 who later became a U.S. permanent resident, was arrested on charges of fraud as he tried to...foreign journalists. These include permitting 46 Hongying Wang and Xueyi Chen...2008. 48 Hongying Wang and Xueyi Chen, “Globalization and the Changing State-Media Relations in China,” op. cit.; Christopher Walker and Sarah Cook

  16. China’s Aircraft Carrier Ambitions: An Update

    DTIC Science & Technology

    2010-01-01

    Takeoff?” Xiandai junshi [Contemporary Military], no. 6 (2006); Liu Jiangping, Jiang Yongjun , and Yang Zhen, “Medium-Sized Aircraft Carrier Has...Defense University. 36. See Deng Taihong and Wang Yingchao, “Exploring the Origins of the Differences between U.S. and Russian Aircraft Carriers in...Active Service,” Shipborne Weapons, 6 June 2008; Liu, Jiang, and Yang, “Medium-Sized Aircraft Carrier.” 37. Deng and Wang , “Exploring the Origins

  17. The Role of Fanconi/BRCA DNA Repair Pathway in Epithelial Ovarian Carcinogenesis

    DTIC Science & Technology

    2015-01-01

    linking agents, including cisplatin . In fact, increased chromosomal breakage in response to DNA cross-linkers (mitomycin C and diepoxybutane) is the...BRCA pathway in cisplatin -sensitive ovarian tumors. Nat Med 9, 568-574 (2003). 14 Wang, Z., Li, M., Lu, S., Zhang, Y. & Wang, H. Promoter...management of ovarian cancer. Ann Oncol, 22 Suppl 8, viii5. D’ANDREA, A.D. (2003). The Fanconi Anemia/BRCA signaling pathway: disruption in cisplatin

  18. Rotorcraft System Identification (Identification des Systemes de Voilures Tournantes)

    DTIC Science & Technology

    1991-10-01

    139, 1985. DuVal, R.W., Wang , .C. and Demiroz, M.Y.: A Practtcal Approach to Rotorcraft Systems Padfield, G.D., Thorne, R., Murray-Smith, D...an experimentel verification of the Kalman filter iRA)YOUG, PETER, (AB)PATTOn, ROALD J implementation, sod an experimental evaluation of filter...The estimation of the measurements wlth the RSRA compound helicopter parameter values in this model (the stability and control derivatives) (AA) WANG

  19. The Art of Peace: Dissuading China from Developing Counter Space Weapons

    DTIC Science & Technology

    2005-06-01

    Security,” ad Astra, The Magazine of the National Space Society. http://www.space.com/adastra/china_implications_0505.html (accessed 30 May 05) 56 Wang ...dependency. 71 Sagdeev, Roald , “Space Weapons and Space Navigation,” U.S. Space Operations in the...Hucheng, Wang , "The U.S. Military’s ’Soft Ribs’ and Strategic Weaknesses," Liaowang, Vol. 27, reprinted in Xinhua Hong Kong Service, July 5, 2000

  20. A Calculator Controlled Microwave Network Analyzer System.

    DTIC Science & Technology

    1977-03-01

    A Hewlett Packard 8410S (Option 310) Microwave Network Analyzer System and the input/output interface to a Wang 600-14 Programmable Calculator are described. The original design of a digital to analog interface between the Wang 600-14 Calculator and a HP 8690B Sweep Oscillator is presented. Two system software programs which implement automatic S-parameter data collection and either external data storage or data reduction and display are described and documented. (Author)

  1. Classifying superpotentials: Three summands case

    NASA Astrophysics Data System (ADS)

    Dancer, A.; Wang, M.

    2011-03-01

    We give an overview of our classification results in Dancer and Wang (2005, 2008) [1,2] for superpotentials of scalar curvature type of the cohomogeneity one Ricci-flat equations. We then give an account of the classification in the case where the isotropy representation of the principal orbit consists of exactly three distinct irreducible real summands—the left over case from Dancer and Wang (2008) [2].

  2. Properties of the State of the Art of Bulk III-V Nitride Substrates and Homoepitaxial Layers

    DTIC Science & Technology

    2010-01-01

    Schwalter L J, Susterman Y, Wang R, Bhat I, Arunmozhi G and Slack G A 2000 Appl. Phys. Lett. 76 985 [25] Schwalter L J, Rojo J C, Slack G A, Susterman Y...Wang R, Bhat I and Arunmozhi G 2000 J. Cryst. Growth 211 78 [26] Rojo J C, Slack G A, Morgan K, Raghothamachar B, Dudley M and Schwalter L J 2000 J

  3. Supplement to the knowledge of the genus Batraxis Reitter (Coleoptera: Staphylinidae: Pselaphinae) of China.

    PubMed

    Wang, Dan; Yin, Zi-Wei

    2016-10-28

    Following our previous contributions to the knowledge of Chinese Batraxis Reitter (Wang et al. 2016; Wang & Yin 2016), here we describe two more species from Yunnan, and provide new collecting records for two previously described species, based on the newly available material deposited in the National Museum, Prague, Czech Republic. The number of Batraxis species now reaches 63 species, 19 of them are known to occur in China.

  4. China Report, Political, Sociological and Military Affairs, No. 428

    DTIC Science & Technology

    2007-11-02

    concerned. From the very beginning, comrades like Bai Qing- qiang and others had an incorrect view and feeling toward the letter written to NANFANG...mass line. Comrade Ren Zhongyi expressed the hope that everybody would express his views fully and speak his mind freely. Secretary Wang Ning [3769...Zhong- yi, Li Jianzhen [2621 1017 4176], Xie Fei [6200 7236], Wu Nansheng [0702 0589 3932], Wang Ning, Yin Linping [2651 1627 1755], Kou Qingyan [1379

  5. China Report, Economic Affairs, No. 353

    DTIC Science & Technology

    1983-06-20

    May 83) 3 AGGREGATE ECONOMIC DATA Shanghai Mayor on Municipality’s Development ( Wang Daohan; CHINA DAILY, 28 May 83) 5 Briefs Steel...Beijing CHINA DAILY in English 28 May 83 SHANGHAI CONSTRUCTION SUPPLEMENT pi [Article by Shanghai Mayor Wang Daohan: "A New-Look City Striving for a...Country" special column by XINHUA reporter Fei Qiang : "Make New Clothes for the 1 Billion People—A Visit to the Construction Site of Yizheng Chemical

  6. Dynamic exponents for potts model cluster algorithms

    NASA Astrophysics Data System (ADS)

    Coddington, Paul D.; Baillie, Clive F.

    We have studied the Swendsen-Wang and Wolff cluster update algorithms for the Ising model in 2, 3 and 4 dimensions. The data indicate simple relations between the specific heat and the Wolff autocorrelations, and between the magnetization and the Swendsen-Wang autocorrelations. This implies that the dynamic critical exponents are related to the static exponents of the Ising model. We also investigate the possibility of similar relationships for the Q-state Potts model.

  7. Provable Security of Communication for Protecting Information Flow in Distributed Systems

    DTIC Science & Technology

    2015-06-01

    Fiber,”  IEEE  Trans.  on  Communications,   62(3): 1080 -­‐90,  March,  2014.   15) S.  Shang,  T.  Wang,  P.  Cuff,  S...Physical Layer Secrecy in Multimode Fiber,” IEEE Trans. on Communications, 62(3): 1080 -90, March, 2014. 15) S. Shang, T. Wang, P. Cuff, S. Kulkarni

  8. Retraction.

    PubMed

    2016-11-01

    This article has been retracted at the request of: Editor-in-Chief and Author 'TW-37, a small-molecule inhibitor of Bcl-2, inhibits cell growth and invasion in pancreatic cancer' by Wang, Z., Song, W., Aboukameel, A., Mohammad, M., Wang, G., Banerjee, S., Kong, D., Wang, S., Sarkar, F. H. and Mohammad, R. M. The above article, published online on 4 June 2008, in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the authors, the journal Editor-in-Chief, Professor Peter Lichter, and Wiley Periodicals, Inc. A university investigation involving the first and the second-to-last author determined that several figures from another published paper were manipulated or duplicated and re-used in this paper. Therefore, the authors are retracting the paper in its entirety although they maintain that these issues did not affect the major conclusions. They apologize for any inconvenience this may have caused. Reference Wang, Z., Song, W., Aboukameel, A., Mohammad, M., Wang, G., Banerjee, S., Kong, D., Wang, S., Sarkar, F. H. and Mohammad, R. M. (2008), TW-37, a small-molecule inhibitor of Bcl-2, inhibits cell growth and invasion in pancreatic cancer. Int. J. Cancer, 123: 958-966. doi: 10.1002/ijc.23610.

  9. Development of a Marx-coupled trigger generator with high voltages and low time delay

    NASA Astrophysics Data System (ADS)

    Hu, Yixiang; Zeng, Jiangtao; Sun, Fengju; Cong, Peitian; Su, Zhaofeng; Yang, Shi; Zhang, Xinjun; Qiu, Ai'ci

    2016-10-01

    Coupled by the Marx of the "JianGuang-I" facility, a high voltage, low time-delay trigger generator was developed. Working principles of this trigger generator and its key issues were described in detail. Structures of this generator were also carefully designed and optimized. Based on the "JianGuang-I" Marx generator, a test stand was established. And a series of experiment tests were carried out to the study performance of this trigger generator. Experiment results show that the output voltage of this trigger generator can be continuously adjusted from 58 kV to 384 kV. The time delay (from the beginning of the Marx-discharging pulse to the time that the output pulse of the trigger generator arises) of this trigger pulse is about 200 ns and its peak time (0%˜100%) is less than 50 ns. Experiment results also indicate that the time-delay jitter of trigger voltages decreases rapidly with the increase in the peak voltage of trigger pulses. When the trigger voltage is higher than 250 kV, the time-delay jitters (the standard deviation) are less than 7.7 ns.

  10. Development of a Marx-coupled trigger generator with high voltages and low time delay.

    PubMed

    Hu, Yixiang; Zeng, Jiangtao; Sun, Fengju; Cong, Peitian; Su, Zhaofeng; Yang, Shi; Zhang, Xinjun; Qiu, Ai'ci

    2016-10-01

    Coupled by the Marx of the "JianGuang-I" facility, a high voltage, low time-delay trigger generator was developed. Working principles of this trigger generator and its key issues were described in detail. Structures of this generator were also carefully designed and optimized. Based on the "JianGuang-I" Marx generator, a test stand was established. And a series of experiment tests were carried out to the study performance of this trigger generator. Experiment results show that the output voltage of this trigger generator can be continuously adjusted from 58 kV to 384 kV. The time delay (from the beginning of the Marx-discharging pulse to the time that the output pulse of the trigger generator arises) of this trigger pulse is about 200 ns and its peak time (0%∼100%) is less than 50 ns. Experiment results also indicate that the time-delay jitter of trigger voltages decreases rapidly with the increase in the peak voltage of trigger pulses. When the trigger voltage is higher than 250 kV, the time-delay jitters (the standard deviation) are less than 7.7 ns.

  11. The fauna of the family Bombycidae sensu lato (Insecta, Lepidoptera, Bombycoidea) from Mainland China, Taiwan and Hainan Islands.

    PubMed

    Wang, Xing; Wang, Min; Zolotuhin, Vadim V; Hirowatari, Toshiya; Wu, Shipher; Huang, Guo-Hua

    2015-07-22

    Seventy-seven species of family Bombycidae s. lat., belonging to 25 genera in three subfamilies, that have been recorded from China are listed and described, with illustrations of the adults, preimaginal stages (if available), and their genitalia. Keys to subfamilies and genera are provided. Two new genera and four new species are described, two subgenera are raised to generic status, seven new combinations are made, and one genus and six species are newly recorded from China. The new taxa are as follows: Rotunda Wang, X. & Zolotuhin, gen. nov., Comparmustilia Wang, X. & Zolotuhin, gen. nov., Triuncina daii Wang, X. & Zolotuhin, sp. nov., Triuncina xiongi Wang, X. & Zolotuhin, sp. nov., Gnathocinara boi Wang, X. & Zolotuhin, sp. nov. and Promustilia yajiangensis Wang, X. & Zolotuhin, sp. nov. The taxa newly recorded for China are: Sesquiluna Forbes, 1955; Trilocha friedeli Dierl, 1978; Bivincula kalikotei Dierl, 1978; Sesquiluna forbesi Zolotuhin & Witt, 2009; Mustilizans lepusa Zolotuhin, 2007; Smerkata brechlini (Zolotuhin, 2007) and Mustilia castanea Moore, 1879. The seven new combinations are: Rotunda rotundapex (Miyata & Kishida, 1990), comb. nov., Triuncina nitida (Chu & Wang, L.Y., 1993), comb. nov., Gunda sesostris (Vuillot, 1893), comb. nov., Smerkata fusca (Kishida, 1993), comb. nov., Comparmustilia sphingiformis (Moore, 1879), comb. nov., Comparmustilia semiravida (Yang, 1995), comb. nov., Comparmustilia gerontica (West, 1932), comb. nov.. The two subgenera raised to generic level are: Promustilia Zolotuhin, 2007, stat. nov. and Smerkata Zolotuhin, 2007, stat. nov.. The distributions of the species in China were determined and distributional maps provided. All type specimens of the new species described here are deposited in the College of Plant Protection, Hunan Agricultural University, China (HUNAU); Department of Entomology, South China Agricultural University, China (SCAU); Kyushu University Museum, Kyushu University, Japan (KUM), and Entomological

  12. A review of the leafhopper genus Scaphotettix Matsumura (Hemiptera: Cicadellidae: Deltocephalinae), with description of a new genus.

    PubMed

    Dai, Wu; Viraktamath, C A; Zhang, Yalin; Webb, M D

    2009-09-01

    The leafhopper genus Scaphotettix Matsumura is redescribed, and three new species are described and Illustrated: S. striatus Dai and Zhang, sp. nov. from Java (on bamboo) and China; S. bispinosus Dai and Zhang, sp. nov from China; and S. pectinatus Dai and Zhang, sp. nov. from Vietnam. Most other species of Scaphotettix were re-examined and found to belong to a new genus also described herein, Scaphomonus Viraktamath, gen. nov.. The new genus is compared with the superficially similar Melanetettix Knight and Fletcher, Scaphodhara Viraktamath and Mohan, and Scaphoideus Uhler and a new species, Scaphomonus vateriae Viraktamath, sp. nov. from India, is described and Illustrated. In addition, the following new combinations are proposed (all previously placed in Scaphotettix): Scaphomonus agumbensis (Viraktamath and Mohan) comb, nov.; S. arcuatus (Viraktamath and Mohan) comb, nov.; S. freytagi (Viraktamath and Mohan) comb, nov.; S. indicus (Distant) comb, nov.; S. longistylus (Li and Wang) comb, nov.; S. mainadicus (Viraktamath and Mohan) comb, nov.; S. quadrifidus (Viraktamath and Mohan) comb, nov.; S. redundans (Distant) comb, nov.; and S. splinterus (Li and Wang) comb. nov. Three species, Scaphotettix fanjingensis Li and Wang, Scaphotettix redstripeus Li and Wang, and Scaphotettix sienderus Li and Wang, do not belong to the genus Scaphotettix and are not treated further. Keys are provided for species of both Scaphotettix and Scaphomonus.

  13. Path Crossings with Lars Onsager

    NASA Astrophysics Data System (ADS)

    Yang, Chen Ning

    2013-05-01

    I first heard of Onsager's name from my M.S. degree thesis adviser J. S. Wang in Kunming, China. Wang had studied the theory of order-disorder transitions with R. H. Fowler in Cambridge, England in the 1930's. He told me one day in 1944-45 that Onsager had produced an exact solution of the Ising model in two dimensions. Wang was a quiet and reserved person. But that day he was evidently quite excited. I can remember still today, half a century later, the tone of admiration bordering on agitation with which he told me about Onsager's paper. I then looked up the paper [26J, but did not understand the strategic plan of Onsager's method. Onsager seemed to have a predilection for calculating commutators at every possible turn without supplying the reasons for so doing...

  14. [Hua Shou's social circle and his accomplishments and good medical reputation].

    PubMed

    Wang, J L

    2016-07-28

    Hua Shou was a very famous physician at the turn of the Yuan and Ming Dynasties. In addition to his medical skills, his social communication was also very helpful to his fame. Under the tutorship of the Confucianist Han Shuo, and physicians such as Wang Jüzhong and Gao Dongyang in his early days, Hua Shou obtained two identities: Confucian scholar and doctor. The former helped Hua Shou get acceptance from literati group, meanwhile, Hua Shou's medical skill helped him deepen the communication among them. By means of his double identity, Hua Shou got acquaintance with many local and nation-wide scholars and politicians, including Zhao Lian, Chen Xingzhong, Wang Shuyu, Fang Guozhen, Song Xuanxi, Zhu You, Wang Xiyang, Song Lian, Liu Ji, through them Hua Shou's fame spread throughout the country. The whole set of"Lin xia"(Hermit identity) constructed by Ding Henian, Liu Renben and Dai Liang, help Hua Shou attain his bequeathed reputation.

  15. A dietary polyphenol resveratrol acts to provide neuroprotection in recurrent stroke models by regulating AMPK and SIRT1 signaling, thereby reducing energy requirements during ischemia.

    PubMed

    2016-04-01

    The above article from European Journal of Neuroscience, published online on 5 March 2013 in Wiley Online Library (http://onlinelibrary.wiley.com/doi/10.1111/ejn.12162/full), has been retracted by agreement between the Editors-in-Chief, Paul Bolam and John Foxe, the authors and John Wiley & Sons Ltd. The retraction has been agreed as Dr Phillip Barber has informed the publisher that he had seen neither the original data nor any version of the manuscript, and had not been involved in the work reported. A subsequent Institutional investigation found evidence of misconduct on the part of the submitting author. Reference Wang, L.-M., Wang, Y.-J., Cui, M., Luo, W.-J., Wang, X.-J., Barber, P.A. & Chen, Z.-Y. (2013) A dietary polyphenol resveratrol acts to provide neuroprotection in recurrent stroke models by regulating AMPK and SIRT1 signaling, thereby reducing energy requirements during ischemia.

  16. A fully relativistic study of the Pt(CN)42- and Pt(CN)62- photodetachment spectra

    NASA Astrophysics Data System (ADS)

    Pernpointner, Markus

    2007-09-01

    In this work the photoelectron spectra of the doubly charged transition metal complexes Pt(CN)42- and Pt(CN)62- are calculated by application of the one-particle propagator method in a fully relativistic framework. In systems with highly relativistic atoms spin-orbit coupling, electron correlation and scalar relativistic effects are hereby coupled in an intricate way and need to be treated consistently in order to obtain accurate results. The obtained ionization spectra are in very good agreement to experiment and the first ionization potentials were calculated as 1.40 eV for Pt(CN)42- and 4.00 eV for Pt(CN)62- compared to the experimental values of 1.69 eV and 4.01 eV [X.B. Wang, Y.L. Wang, H.K. Woo, J. Li, G.S. Wu, L.S. Wang, Chem. Phys. 329 (2006) 230].

  17. Non-human lnc-DC orthologs encode Wdnm1-like protein

    PubMed Central

    Dijkstra, Johannes M.; Ballingall, Keith T.

    2014-01-01

    In a recent publication in Science, Wang et al. found a long noncoding RNA (lncRNA) expressed in human dendritic cells (DC), which they designated lnc-DC. Based on lentivirus-mediated RNA interference (RNAi) experiments in human and murine systems, they concluded that lnc-DC is important in differentiation of monocytes into DC. However, Wang et al. did not mention that their so-called “mouse lnc-DC ortholog” gene was already designated “ Wdnm1-like” and is known to encode a small secreted protein.  We found that incapacitation of the Wdnm1-like open reading frame (ORF) is very rare among mammals, with all investigated primates except for hominids having an intact ORF. The null-hypothesis by Wang et al. therefore should have been that the human lnc-DC transcript might only represent a non-functional relatively young evolutionary remnant of a protein coding locus.  Whether this null-hypothesis can be rejected by the experimental data presented by Wang et al. depends in part on the possible off-target (immunogenic or otherwise) effects of their RNAi procedures, which were not exhaustive in regard to the number of analyzed RNAi sequences and control sequences.  If, however, the conclusions by Wang et al. on their human model are correct, and they may be, current knowledge regarding the Wdnm1-like locus suggests an intriguing combination of different functions mediated by transcript and protein in the maturation of several cell types at some point in evolution. We feel that the article by Wang et al. tends to be misleading without the discussion presented here. PMID:25309733

  18. Information Leakage in Efficient Bidirectional Quantum Secure Direct Communication with Single Photons in Both Polarization and Spatial-Mode Degrees of Freedom

    NASA Astrophysics Data System (ADS)

    Zhang, Cai; Situ, Haozhen

    2016-11-01

    Recently, Wang et al. presented a bidirectional quantum secure direct communication protocol with single photons in both polarization and spatial-mode degrees of freedom (Int. J. Theor. Phys. 54(10): 3443-3453, 2015). They claimed that their protocol was efficient and removed the drawback of information leakage. However, we found that the information leakage actually exists in their protocol. In this paper, we analyze Wang et al.'s protocol in detail. In addition, we propose an improvement to avoid the information leakage. The security of the improved protocol has also been discussed.

  19. The China Factor in U.S.-Vietnam Relations

    DTIC Science & Technology

    2012-03-01

    02/22/blogging-while-vietnamese; Fan Hongxing, Liu Chang, and Wang Huicong, “Vietnam Makes Use of South China Sea Issue To Rope in Big-Power...Mekong by holding back silt and preventing the downstream flow of alluvial needed to fertilize the delta, enrich the soil, wash out salts, and limit...The New York Times, 23 Apr 2010, www.nytimes.com/2010/04/24/world/asia/24navy.html. Fan Hongxing, Liu Chang, and Wang Huicong, “Vietnam Makes Use

  20. The Detection and Study of Molecular Species Using Time Resolved Laser Spectroscopy

    DTIC Science & Technology

    1988-07-01

    of 0 ," A. Sir ,. C.V. Ramana, W.A. Chupka and S.D. Colson, J. C.em. Phys. 84, 69 (1986). "Direct Observation of Photochemical Pathways in Ammonia by...Graduate Students: Joan Pallix (Received Ph.D) Yumin Wang Postdoctoral Fellow: James LoBue . ...... .... ~... . . . .. . . .. . .- - -I- Final...Y. Wang, P. Chen and S.D.Culson, (unpublished). 17. M.J.S. Dewar , J.P.Ritchie and J. Alster, J. Org. Chem. 50, 1031 (1985). 18. A.M. Wodtke, E.J. Hintsa and Y.T. Lee, J. Phys. Chem. 90, 3549 (1986). ATE L EDM 7-

  1. On the equivalence of LIST and DIIS methods for convergence acceleration

    NASA Astrophysics Data System (ADS)

    Garza, Alejandro J.; Scuseria, Gustavo E.

    2015-04-01

    Self-consistent field extrapolation methods play a pivotal role in quantum chemistry and electronic structure theory. We, here, demonstrate the mathematical equivalence between the recently proposed family of LIST methods [Wang et al., J. Chem. Phys. 134, 241103 (2011); Y. K. Chen and Y. A. Wang, J. Chem. Theory Comput. 7, 3045 (2011)] and the general form of Pulay's DIIS [Chem. Phys. Lett. 73, 393 (1980); J. Comput. Chem. 3, 556 (1982)] with specific error vectors. Our results also explain the differences in performance among the various LIST methods.

  2. Methylselenium and Prostate Cancer Apoptosis

    DTIC Science & Technology

    2008-02-01

    Reportable outcomes 1) Hongbo Hu, Guang-xun Li, Lei Wang, Jennifer Watts, Gerald F Combs, Jr, and Junxuan Lü. Methylseleninic acid enhances taxane...1LeiWang,1JenniferWatts,2 Gerald F. Combs, Jr.,2 andJunxuan Lu« 1 Abstract Purpose: Our previous work has shown that methylseleninic acid (MSeA) sensitized...andVitamin ECancer PreventionTrial (SELECT). JNatl Cancer Inst 2005;97:94^102. 33. Karp DD. ECOG 5597: phase III chemoprevention trial of selenium

  3. Application of Entry-Time Processes in Asset Management for Nuclear Power Plants (Final Report)

    SciTech Connect

    Paul Nelson

    2008-01-23

    A mathematical model of entry-time processes was developed, and a computational method for solving that model was verified. This methodology was demonstrated via application to a succession of increasingly more complex subsystems of nuclear power plants. The effort culminated in the application to main generators that constituted the PhD dissertation of Shuwen (“Eric”) Wang. Dr. Wang is now employed by ABS Consulting, in Anaheim, CA. ABS is a principal provider to the nuclear industry of technical services related to reliability and safety.

  4. Quantitative Separation of Single-Walled Carbon Nanotubes into Metallic and Semiconducting Fractions

    DTIC Science & Technology

    2012-08-15

    Boron Nitride Nanocomposite Materials for Superior Thermal Transport Performance ” Angew. Chem. Int. Ed. 2012, 51, 6498–6501. (12) Song, W.-L.; Wang, W...Veca, L. M.; Kong, C. Y.; Cao, M.-S.; Wang, P.; Meziani, M. J.; Qian, H.; LeCroy, G. E.; Cao, L.; Sun, Y.-P. “ Polymeric /Carbon Nanocomposites for... PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10

  5. Evaluation of two Vaisala RS92 radiosonde solar radiative dry bias correction algorithms

    DOE PAGES

    Dzambo, Andrew M.; Turner, David D.; Mlawer, Eli J.

    2016-04-12

    Solar heating of the relative humidity (RH) probe on Vaisala RS92 radiosondes results in a large dry bias in the upper troposphere. Two different algorithms (Miloshevich et al., 2009, MILO hereafter; and Wang et al., 2013, WANG hereafter) have been designed to account for this solar radiative dry bias (SRDB). These corrections are markedly different with MILO adding up to 40 % more moisture to the original radiosonde profile than WANG; however, the impact of the two algorithms varies with height. The accuracy of these two algorithms is evaluated using three different approaches: a comparison of precipitable water vapor (PWV), downwellingmore » radiative closure with a surface-based microwave radiometer at a high-altitude site (5.3 km m.s.l.), and upwelling radiative closure with the space-based Atmospheric Infrared Sounder (AIRS). The PWV computed from the uncorrected and corrected RH data is compared against PWV retrieved from ground-based microwave radiometers at tropical, midlatitude, and arctic sites. Although MILO generally adds more moisture to the original radiosonde profile in the upper troposphere compared to WANG, both corrections yield similar changes to the PWV, and the corrected data agree well with the ground-based retrievals. The two closure activities – done for clear-sky scenes – use the radiative transfer models MonoRTM and LBLRTM to compute radiance from the radiosonde profiles to compare against spectral observations. Both WANG- and MILO-corrected RHs are statistically better than original RH in all cases except for the driest 30 % of cases in the downwelling experiment, where both algorithms add too much water vapor to the original profile. In the upwelling experiment, the RH correction applied by the WANG vs. MILO algorithm is statistically different above 10 km for the driest 30 % of cases and above 8 km for the moistest 30 % of cases, suggesting that the MILO correction performs better than the WANG in clear-sky scenes

  6. Quasi-local energy in presence of gravitational radiation

    NASA Astrophysics Data System (ADS)

    Chen, Po-Ning; Wang, Mu-Tao; Yau, Shing-Tung

    2016-07-01

    We discuss our recent work [P.-N. Chen, M.-T. Wang and S.-T. Yau, Quasi-local mass in the gravitational perturbations of black holes, to appear.] in which gravitational radiation was studied by evaluating the Wang-Yau quasi-local mass of surfaces of fixed size at the infinity of both axial and polar perturbations of the Schwarzschild spacetime, à la Chandrasekhar. [S. Chandrasekhar, The Mathematical Theory of Black Holes, Oxford Classic Texts in the Physical Sciences (Oxford University Press, New York, 1998).

  7. Endoplasmic Reticulum-Associated Degradation Factor ERLIN2: Oncogenic Roles and Molecular Targeting of Breast Cancer

    DTIC Science & Technology

    2013-06-01

    that fatty acid synthesis and expression of lipogenic genes in breast c © The Authors Journal compilation c © 2012 Biochemical Society 22 ERLIN2 regulates... gene amplification at 8p12 specifies luminal B breast cancer. EMBO Mol. Med. 3, 153–166 12 Yang, Z. Q., Liu, G., Bollig-Fischer, A., Giroux, C . N. and...with differentiated functions in chemically defined medium. Cancer Res. 42 , 3858–3863 20 Laing, S., Wang, G., Briazova, T., Zhang, C ., Wang, A., Zheng

  8. Radiation-Induce Immune Modulation in Prostate Cancer

    DTIC Science & Technology

    2005-01-01

    Pei Liao,* Chun-Chieh Wang,*Il Lisa H. Butterfield,* James S. Economou,t Antoni Ribas ,t Wilson S. Meng,4 Keisuke S. Iwamoto,* and William H. McBride2...prostate cancer model. Int. J. Radiat. Oncol. Biol. Phys.. 59:579- 583, 2004. Liao, Y-P., C-C. Wang, L.H. Butterfield, J.S. Economou, A. Ribas , W.S. Meng...A. Ribas and W.H. McBride: Radiation modulates tumor antigen presentation by dendritic cells. In: Abstracts of Papers for the 95 "h Annual Meeting of

  9. Functional oxide nanobelts - from materials to nanodevices

    NASA Astrophysics Data System (ADS)

    Lin, Zhong; Wang

    2003-11-01

    Nanowire and nanotube based materials have been demonstrated as building blocks for nanocircuits, nanosystems and nano-optoelectronics. Recently, ultra-long belt-like, quasi-one-dimensional nanostructures (so called nanobelts or nanoribbons) have been successfully synthesized for semiconducting oxides of zinc, tin, indium, cadmium and gallium, by simply evaporating the desired commercial metal oxide powders at high temperatures [1]. The as-synthesized oxide nanobelts are pure, structurally uniform, single crystalline and most of them free from dislocations; they have a rectangular-like cross-section with typical widths of 30 - 300 nm, width-to-thickness ratios of 5 - 10 and lengths of up to a few millimeters. The belt-like morphology appears to be a unique and common structural characteristic for the family of semiconducting oxides with cations of different valence states and materials of distinct crystallographic structures. Using the technique demonstrated for measuring the mechanical properties of carbon nanotubes based on in-situ transmission electron microscopy [2,3], the bending modulus of the oxide nanobelts has been measured and the nanobelt is shown to be a dual mode nanoresonator for NEMS technology. Field effect transistors [4] and ultra-sensitive nano-size gas sensors [5], nanoresonators and nanocantilevers [6] have also been fabricated based on individual nanobelts. Thermal transport along the nanobelt has also been measured. Nanocantilevers based on nanobelts have been fabricated. Very recently, structurally nanobelts exhibiting piezoelectric and ferroelectric properties have been synthesized, which could be a candidate for nano-scale traducers, actuators and sensors. [1] Z.W. Pan, Z.R. Dai and Z.L. Wang, Science, 209 (2001) 1947. [2] P. Poncharal, Z.L. Wang, D. Ugarte and W.A. de Heer, Science, 283 (1999) 1513; Electron Microscopy of Nanotubes, ed. Z.L. Wang and C. Hui, Kluwer Academic Publisher (2003). [3] R.P. Gao, Z.L. Wang, Z.G. Bai, W. de Heer

  10. Exploring the Mechanisms of Pathogenesis in Prostate Cancer Involving TMPRSS2-ERG (Or ETV1) Gene Rearrangement

    DTIC Science & Technology

    2009-01-01

    Esther Baena, PhD; Zhe Li, PhD. Conclusion: We planned to use both a series of mouse models and biochemical approaches to study the mechanisms of...Apr 1, 2006). 9. S. A. Tomlins et al., Science 310, 644 (Oct 28, 2005). 10. J. Wang , Y. Cai, C. Ren, M. Ittmann, Cancer Res 66, 8347 (Sep 1, 2006...Cancer Res 68, 3584 (May 15, 2008). 23. S. Wang et al., Cancer Cell 4, 209 (Sep, 2003). 24. Y. Y. Kisanuki et al., Dev Biol 230, 230 (Feb 15, 2001

  11. Development of Data-Assimilation-Quality MODIS and MISR Over Ocean Aerosol Products

    DTIC Science & Technology

    2009-08-01

    graduate students in the Atmospheric Sciences Department, especially Prof. David Delene, Aaron Kennedy, Hongchun Jin, and Zhe Feng, for their technical...properties, as well as impact air quality (e.g. Wang and Christopher, 2003) and visibility (e.g. Appel et al., 1985). Studies have found that aerosols...16,988, July 27. 1997. Tong, Y. P., G. L. Zhang, M. G. Tan, W. Wang , J. M. Chen, Y. Hwu, P. C. Fsu, J. H. Je., G. Margaritondo, W. M. Song, R. F

  12. Comment on “Scaling behavior of one-dimensional Pt chains migration on Pt(110)-(1×2) surface”. [Phys. Lett. A 268 (2000) 413

    NASA Astrophysics Data System (ADS)

    Montalenti, F.; Ferrando, R.

    2000-11-01

    We show that the recently proposed scaling laws [see G. Zhuang, W. Wang, Phys. Lett. A 268 (2000) 413] for chain diffusion on missing-row Pt(110) have no real meaning, since they cannot be extended outside the narrow chain-length range which has been considered by Zhuang and Wang. The only asymptotic scaling law gives a chain mobility which is inversely proportional to the chain length; however this asymptotic scaling behaviour is not physically important due to the occurrence of multiple upward promotions for long chains.

  13. Nucleation and Growth Control of ZnO via Impurity-mediated Crystallization

    DTIC Science & Technology

    2015-01-02

    Characteristics of Crystalline Silicon/Si Quantum Dot/Poly(3,4-ethylenedioxythiophene) Hybrid Solar Cells ”, G. Uchida, Y. Wang, D. Ichida, H. Seo, K. Kamataki, N...Electron Transfer of Dye-Sensitized Solar Cell Using Vanadium Doped TiO2 ”, H. Seo, Y. Wang, D. Ichida, G. Uchida, N. Itagaki, K. Koga, M. Shiratani, S...conductive oxide (TCO) in flat-panel displays, touch screens on smartphones, organic light-emitting diodes (OLEDs), solar cells , etc [1-6]. The resistivity

  14. Review of the Fannia postica-group Chillcott, 1961 of the genus Fannia Robineau-Desvoidy, 1830, with description of two new species from the Palearctic and Oriental regions (Diptera, Fanniidae)

    PubMed Central

    Wang, Ming-fu; Li, Wei; Zhu, Wei-bing; Zhang, Dong

    2016-01-01

    Abstract A total of 17 species of the Fannia postica-group Chillcott, 1961 from the Palearctic and Oriental regions are reviewed herein, 2 of which are described from China as new: Fannia ningxiaensis Wang & Zhang, sp. n. and Fannia subaethiops Wang & Zhu, sp. n.. Fannia labidocerca Feng & Xue, 2006, originally placed in Fannia serena-group Chillcott, 1961, is moved to the postica-group and re-described. An identification key to the males of known species from these regions is provided. PMID:27408593

  15. Metagenomic profiles of free-living archaea, bacteria and small eukaryotes in coastal areas of Sichang island, Thailand

    PubMed Central

    2012-01-01

    Background Tha Wang and Tham Phang coasts, though situated at similar oceanographic positions on Sichang island, Chonburi province, Thailand, are different in bay geography and amount of municipal disturbances. These affect the marine ecosystems. The study used metagenomics combined with 16S and 18S rDNA pyrosequencing to identify types and distributions of archaea, bacteria, fungi and small eukaryotes of sizes ranges 0.45 and ~30 μm. Results Following the open bay geography and minimal municipal sewages, Tham Phang coast showed the cleaner water properties, described by color, salinity, pH, conductivity and percent dissolved oxygen. The 16S and 18S rDNA metagenomic profiles for Tha Wang and Tham Phang coasts revealed many differences, highlighting by low Lennon and Yue & Clayton theta similarity indices (66.03-73.03% for 16S rDNA profiles, 2.85-25.38% for 18S rDNA profiles). For 16S rDNA, the percent compositions of species belonging to Proteobacteria, Bacteroidetes, Cyanobacteria, Firmicutes, Verrucomicrobia, Gammatimonadetes, Tenericutes, Acidobacteria, Spirochaetes, Chlamydiae, Euryarchaeota, Nitrospirae, Planctomycetes, Thermotogae and Aquificae were higher or distinctly present in Tha Wang. In Tham Phang, except Actinobacteria, the fewer number of prokaryotic species existed. For 18S rDNA, fungi represented 74.745% of the species in Tha Wang, whereas only 6.728% in Tham Phang. Basidiomycota (71.157%) and Ascomycota (3.060%) were the major phyla in Tha Wang. Indeed, Tha Wang-to-Tham Phang percent composition ratios for fungi Basidiomycota and Chytridiomycota were 1264.701 and 25.422, respectively. In Tham Phang, Brachiopoda (lamp shells) and Mollusca (snails) accounted for 80.380% of the 18S rDNA species detected, and their proportions were approximately tenfold greater than those in Tha Wang. Overall, coastal Tham Phang comprised abundant animal species. Conclusions Tha Wang contained numerous archaea, bacteria and fungi, many of which could synthesize

  16. Journal of Engineering Thermophysics (Selected Articles),

    DTIC Science & Technology

    1986-06-24

    were extracted from the best quality copy available. ,6 I 6 a 9 ii - FS- -7 P R :! ’ -N OF A S:NGLE STAGE -OMPRESSCP Duan .nfeng, .. ng Baochang, Wang...e ; . . . . w -.. .. -- :" 4 _- / S 3_ -_ 701 0 .0 .. 0. 4 0.6 . P , 0 . Fig.6(a) Radial -fitribution of flow paraneters at the outlet of rotor. le...flow line; 2rotor without part span rhrou 3:Kg/Fec; 4:rotnr with part Tran shroud) too," I I.I i I n. 11 , ’ ,5 £4 7 - " P -- +7 ----z+ -- 60 20 , 0.6

  17. Molecular Innovations Toward Theranostics of Aggressive Prostate Cancer

    DTIC Science & Technology

    2014-09-01

    Phys. Chem. B, 2014, 118, 1696–1706; (d) S. J. Guillaudeu, M. E. Fox , Y. M. Haidar, E. E. Dy, F. C. Szoka and J. M. J. Frechèt, Bioconjugate Chem...R. M. Wolf , J. Liu, X. Wu, S. Brozell, T. Steinbrecher, H. Gohlke, Q. Cai, X. Ye, J. Wang, M.-J. Hsieh, G. Cui, D. R. Roe, D. H. Mathews, M. G...X. Sun and E. E. Simanek, Mol. Pharmaceutics, 2012, 9, 404–412. 15 J. Wang, R. M. Wolf , J. W. Caldwell, P. A. Kollman and D. A. Case, J. Comput. Chem

  18. Structural properties of Alumnum nitride compound

    NASA Astrophysics Data System (ADS)

    Mohammad, R.; Katırcıoğlu, Ş.

    2014-10-01

    Structural properties of Alumnum nitride in wurtzite, zinc-blende and rock-salt phases have been investigated by Full Potential-Linearized Augmented Plane Waves method based on Density Functional Theory within Local Density Approximation and seven Generalized Gradient schemes. It is found that, Alumnum nitride in wurtzite phase is the stable ground state structure and makes a transition to rock-salt phase at a low transition pressure (11.54 GPa). According to present total energy calculations, zinc-blende phase of Alumnum nitride also makes a transition to rock-salt phase, at a low transition pressure (10.17 GPa). Generalized Gradient functionals of Perdew-Wang-Engel-Vosko and Perdew-Burke-Ernzerhof are found to be more successful than other approximations considered in this work for providing the closest values of the structural features, such as, lattice constants, bulk moduli, first order pressure derivatives of bulk moduli and cohesive energies of Alumnum nitride three phases to available experimental ones. Although Generalized Gradient approaches of Perdew-Wang-Engel-Vosko, Perdew-Burke-Ernzerhof, Becke-Perdew-Wang and Perdew-Burke-Ernzerhof (revised) are found to be accurate schemes for elastic constants of rock-salt AlN, only Perdew-Wang-Engel-Vosko and Perdew-Burke-Ernzerhof functionals are observed to be more successful than the other schemes for supplying accurately both C_{11} and C_{12} of zinc-blende Alumnum nitride structure. Perdew-Wang-Engel-Vosko functional is observed to be superior to Perdew-Burke-Ernzerhof for elastic constants of wurtzite Alumnum nitride structure. Elastic constants of wurtzite Alumnum nitride obtained by self Perdew-Wang-Engel-Vosko approach and Martin's transformation calculations in which elastic constants of zinc-blende Alumnum nitride are calculated with Perdew-Wang-Engel-Vosko scheme, are very close to the experimental ones. Hence, functional of Perdew-Wang-Engel-Vosko is decided to be the most accurate approximation

  19. Functional Characterization of a Novel Prostate-Specific Gene PrLZ in Prostate Cancer

    DTIC Science & Technology

    2006-01-01

    interaction with the novel and prostate-specific PrLZ protein. Jianchun Xu, Haian Fu, Fray F. Marshall, Haiyen E. Zhau, Leland W. K. Chung , and...REFERENCES JC Xu, HA Fu, FF Marshall, HE Zhau, LWK Chung , and RX Wang (2005). The 14-3-3 protwins: expression in prostate epithelia and interaction with...Appendix 1). AG Baseman, AJ Kirsch, FF Marshall, HE Zhau, LWK Chung , and RX Wang (2005). 14-3-3 expression patterns in the human kidney: from fetal

  20. Data sets for manuscript titled Unexpected benefits of reducing aerosol cooling effects

    EPA Pesticide Factsheets

    These data sets were created using extensive model simulation results from the WRF-CMAQ model, population distributions, and through the use of an health impact assessment model - see manuscript for details.This dataset is associated with the following publication:Xing, J., J. Wang, R. Mathur , J. Pleim , S. Wang, C. Hogrefe , C. Gan, D. Wong , and J. Hao. Unexpected Benefits of Reducing Aerosol Cooling Effects. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, USA, 50(14): 7527–7534, (2016).

  1. Supplemental Information: Phototransformation-Induced Aggregation of Functionalized Single-Walled Carbon Nanotubes: the Importance of Amorphous Carbon

    EPA Pesticide Factsheets

    Additional information about the carboxylated SWCNT calibration curve, AFM images, EDS results, solar simulator light and UVB lamp spectra, TEM image ofparent carboxylated SWCNTs, XPS spectra of the dark control P3 sample and the irradiated P3 sample, and a table summarizing the kinetic parameters (PDF)This dataset is associated with the following publication:Hou, W., C. He, Y. Wang, D. Wang, and R. Zepp. Phototransformation-Induced Aggregation of Functionalized Single-Walled Carbon Nanotubes: The Importance of Amorphous Carbon. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, USA, 50(7): 3494–3502, (2016).

  2. Real-Time Terahertz Imaging Using a Quantum Cascade Laser and Uncooled Microbolometer Focal Plane Array

    DTIC Science & Technology

    2008-06-01

    1] D. Arnone, C. Ciesla, and M. Pepper , “Terahertz imaging comes into view,” Physics World 4, 35-40 (2000). [2] D. M. Mittleman, M. Gupta, R...of the 26th Annu. Int. Conf. of the IEEE (IEEE, 2004), pp. 1302-1305. [16] B. Ferguson , S. Wang, D. Gray, D. Abbott and X. -C. Zhang...using Kirchhoff migration," Opt. Lett. 26, 1513-1515 (2001). [30] B. Ferguson , S. Wang, D. Gray, D. Abbot, and X.-C. Zhang, "T-ray computed

  3. Mesoporous Nitrogen-Doped Carbon-Glass Ceramic Cathodes for Solid-State Lithium-Oxygen Batteries (Postprint)

    DTIC Science & Technology

    2012-01-01

    D.; Yang, J.; Li, R .; Sun, X. Electrochem. Commun. 2011, 13, 668−672. (12) Xiao, J.; Mei, D.; Li, X.; Xu, W.; Wang, D.; Graff, G. L.; Bennett, W. D...Nie, Z.; Saraf, L. V.; Aksay, I. A.; Liu, J.; Zhang, J.-G. Nano Lett. 2011, 11, 5071−5078. (13) Li, Y.; Wang, J.; Li, X.; Geng, D.; Li, R .; Sun, X...Chem. Commun. 2011, 47, 9438−9440. (14) Mitchell, R . R .; Gallant, B. M.; Thompson, C. V.; Shao-Horn, Y. Energy Environ. Sci. 2011, 4, 2952−2958. (15

  4. Alpha-v Integrin Targeted PET Imaging of Breast Cancer Angiogenesis and Low-Dose Metronomic Anti-Angiogenic Chemotherapy Efficacy

    DTIC Science & Technology

    2008-08-01

    Med Mol Imaging (2008) 35:1489–1498 18F-FPPRGD2 and 18F-FDG PET of Response to Abraxane Therapy Xilin Sun1,2, Yongjun Yan1, Shuanglong Liu3, Qizhen...Belotti D, Vergani V, Drudis T, et al. The microtubule-affecting drug paclitaxel has antiangiogenic activity. Clin Cancer Res. 1996;2:1843–1849. 11. Wang J...227–234. 19. Liu Z, Li ZB, Cao Q, Liu S, Wang F, Chen X. Small-animal PET of tumors with 64Cu-labeled RGD-bombesin heterodimer. J Nucl Med. 2009;50:1168

  5. SAGE II Ozone Analysis

    NASA Technical Reports Server (NTRS)

    Cunnold, Derek; Wang, Ray

    2002-01-01

    Publications from 1999-2002 describing research funded by the SAGE II contract to Dr. Cunnold and Dr. Wang are listed below. Our most recent accomplishments include a detailed analysis of the quality of SAGE II, v6.1, ozone measurements below 20 km altitude (Wang et al., 2002 and Kar et al., 2002) and an analysis of the consistency between SAGE upper stratospheric ozone trends and model predictions with emphasis on hemispheric asymmetry (Li et al., 2001). Abstracts of the 11 papers are attached.

  6. ADP Regulates the Structure and Function of the Protein KaiC

    DTIC Science & Technology

    2016-08-11

    AFRL-AFOSR-VA-TR-2016-0294 ADP Regulates the Structure and Function of the Protein KaiC Andy LiWang UNIVERSITY OF CALIFORNIA MERCED 5200 N LAKE RD...REPORT TYPE Final Performance 3. DATES COVERED (From - To) 01 Aug 2013 to 31 Jul 2017 4. TITLE AND SUBTITLE ADP Regulates the Structure and Function of...LiWang lab exploited this in vitro clock system to gain an atomic -resolution understanding of a circadian clock. The rationale is that fundamental

  7. On the equivalence of LIST and DIIS methods for convergence acceleration

    SciTech Connect

    Garza, Alejandro J.; Scuseria, Gustavo E.

    2015-04-28

    Self-consistent field extrapolation methods play a pivotal role in quantum chemistry and electronic structure theory. We, here, demonstrate the mathematical equivalence between the recently proposed family of LIST methods [Wang et al., J. Chem. Phys. 134, 241103 (2011); Y. K. Chen and Y. A. Wang, J. Chem. Theory Comput. 7, 3045 (2011)] and the general form of Pulay’s DIIS [Chem. Phys. Lett. 73, 393 (1980); J. Comput. Chem. 3, 556 (1982)] with specific error vectors. Our results also explain the differences in performance among the various LIST methods.

  8. Tight-Binding and Hueckel Models of Molecular Clusters

    DTIC Science & Technology

    1990-05-01

    Chem. Phys. Lett. 163, 323 (1989); Phys. Rev. Lett. 64, 551 (1990). 16. H. Kupka and K. Jug, Chem. Phys. 130, 23 (1989). 17. Y. Wang , T. F. George...D. M. Lindsay and A. C. Beri, J. Chem. Phys. 86, 3493 (1987). 18. D. M. Lindsay, Y. Wang and T. F. George, J. Chem. Phys. 86, 3500 (1987). 23 Table 1...Department of Chemistry Northwestern University University of California Evanston, IL 60208 Irvine, CA 92717 Professor Frank DiSalvo Professor Roald Hoffmann

  9. Clusters: Link between Molecules and Solids.

    DTIC Science & Technology

    1987-11-01

    John Wiley and Sons, New York, 1944), pp. 254-5. 3. The material in this section was drawn from Y. Wang , T.F. George, D.M. Lindsay and A.C. Bert, J. Chem...Phys. 86, 3493 (1987); D.M. Lindsay, Y. Wang and T.F. George, J. Chem. Phys. 86, 3500 (1987). 4. E. Huckel, Z. Physik 70, 204 (1931); 72, 310 (1931...G. Rubloff Dr. Roald Hoffmann IBM Department of Chemistry Thomas J. Watson Research Center Cornell University P.O. Box 218 Ithaca, New York 14853 U

  10. Optical (Hyper) Polarizabilities of Small Silicon Clusters

    DTIC Science & Technology

    1990-11-01

    and R. E. Sinal- ley, Chem. Phys. Lett. 138. 119 (19S7): A. Kasuva and Y. -Nishina. Z. Phys. D 12, 493 (1989). 5. Y. Wang , N. Herron. WV. Mahler and A...Rev. B 37, 6991 (1988); R. Biswas. C. Z. Wang , C. T. Chan, K. NI. Ho and C. NI. Souk- oulis. Phys. Rev. Lett. 63, 1491 (1989); A. D. Nlistriotis. N...Irvine, CA 92717 Professor Frank DiSalvo Professor Roald Hoffmann Department of Chemistry Department of Chemistry Cornell University Cornell University

  11. Linear and Nonlinear Optical Properties of Small Silicon Clusters

    DTIC Science & Technology

    1990-08-01

    Wang , N. Herron, W. Mahler and A. Suna, J. Opt. Soc. Am. B 6, 808 (1989). 6. Y. Q. Li, C. C. Sung, R. Inguva and C. M. Bowden, J. Opt. Soc. Am. B 6, 814...J. Tersoff, Phys. Rev. B 37, 6991 (1988); R. Biswas, C. Z. Wang , C. T. Chan, K. M. Ho and C. M. Souk- oulis, Phys. Rev. Lett. 63, 1491 (1989); A. D...IL 60208 Irvine, CA 92717 Professor Frank DiSalvo Professor Roald Hoffmann Department of Chemistry Department of Chemistry Cornell University Cornell

  12. Applications of a Kullback-Leibler Divergence for Comparing Non-nested Models

    PubMed Central

    Wang, Chen-Pin; Jo, Booil

    2014-01-01

    Wang and Ghosh (2011) proposed a Kullback-Leibler divergence (KLD) which is asymptotically equivalent to the KLD by Goutis and Robert (1998) when the reference model (in comparison with a competing fitted model) is correctly specified and when certain regularity conditions hold true. While properties of the KLD by Wang and Ghosh (2011) have been investigated in the Bayesian framework, this paper further explores the property of this KLD in the frequentist framework using four application examples, each fitted by two competing non-nested models. PMID:24795532

  13. Photon-phonon synergy: photoacoustic tomography and beyond (Presentation Video)

    NASA Astrophysics Data System (ADS)

    Wang, Lihong V.

    2015-03-01

    Photoacoustic tomography is expected to impact biology and medicine broadly by providing multiscale in vivo functional and molecular imaging of structures ranging from subcellular organelles to organs, enabling a noninvasive look at subcutaneous tissue at a deep level. Lihong Wang holds the Gene K. Beare Distinguished Professorship of Biomedical Engineering at Washington University in St. Louis, and is Editor-in-Chief of the Journal of Biomedical Optics. Wang was awarded the 2015 Britton Chance Biomedical Optics Award for his pioneering technical contributions and visionary leadership in the development and application of photoacoustic tomography, photoacoustic microscopy, and photon transport modeling.

  14. Empirical relations between static and dynamic exponents for Ising model cluster algorithms

    NASA Astrophysics Data System (ADS)

    Coddington, Paul D.; Baillie, Clive F.

    1992-02-01

    We have measured the autocorrelations for the Swendsen-Wang and the Wolff cluster update algorithms for the Ising model in two, three, and four dimensions. The data for the Wolff algorithm suggest that the autocorrelations are linearly related to the specific heat, in which case the dynamic critical exponent is zint,EW=α/ν. For the Swendsen-Wang algorithm, scaling the autocorrelations by the average maximum cluster size gives either a constant or a logarithm, which implies that zint,ESW=β/ν for the Ising model.

  15. Laser Journal (Selected Articles),

    DTIC Science & Technology

    1982-09-10

    OPTICAL PROPERTIES OF SINGLE CRYSTAL SULPHONATED SALICYLIC ACID Wang Gongming, Jiang Xiengmei) Wang Wencheng (Physics Department, Fudan University) A...laser is described. The apparatus structure and some experimental results are reported. MATERIAL AND ELEMENT MAGNETO-OPTIC PROPERTIES OF Pr dYb),(1oAI...Sinica) The 9,,.d of (BiPzGdyb0,(F!AI 1, single crystal thin film at 6328A is as high as 3.69-4.05’/dB . This property has been applied to optical

  16. Can gallium dimer react effectively with three H 2 molecules to form digallane?

    NASA Astrophysics Data System (ADS)

    Moc, Jerzy

    2005-06-01

    Distinct routes of formation of digallane (4) Ga 2H 4 and digallane (6) Ga 2H 6 starting with gallium atoms/H 2 and gallium dimers/H 2 are compared based on the high level ab initio single-reference CCSD(T) and CASSCF based SOCI and hybrid density functional theory calculations of the mechanisms involved. The predicted reaction paths are of relevance to the recent matrix IR studies on the gallium hydrides, notably the extensive one by Wang and Andrews [X. Wang, L. Andrews, J. Phys. Chem. A 107 (2003) 11371] who isolated and assigned the series of mono- and digallium hydrides including the two digallanes.

  17. The Real-Time Mach-Zehnder Interferometer used in Space Experiment

    NASA Astrophysics Data System (ADS)

    Duan, L.; Kang, Q.; Sun, Z. W.; Hu, L.; Cui, H. L.; Lin, H.; Li, G. P.

    2008-08-01

    The optical interference method is a promising technique for measuring temperature, density, and concentration in fluids. The non-intrusive and non-invasive nature of its optical techniques to the measured section are its most outstanding features. However, the adverse experiment environment, especially regarding shaking and vibrating, greatly restricts the application of the interferometer. In the present work, an optical diagnostic system consisting of a Mach-Zehnder interferometer (named after physicists Ludwig Mach) and an image processor has been developed that increases the measuring sensitivity compared to conventional experimental methods in fluid mechanics. An image processor has also been developed for obtaining quantitative results by using Fourier transformation. The present facility has been used in observing and measuring the mass transfer process of a water droplet in EAFP protein solution under microgravity condition provided by the satellite Shi Jian No. 8.

  18. Synthesis of Organic Compounds for Malaria Chemotherapeutic Studies

    DTIC Science & Technology

    1975-10-01

    the following Schemue. (.11 Hr C11 3() N03 3 K%.0 A-4 A-5 A-6 C 1 11--(112)3 -(2H2 el NL i 3 A4A A-BI4 %JIA%~N ,t I,,-’. rominationA’ of veratrole (A-4...80)o A mixture of 69 g (0,5 mole) of veratrole , 80 ml Of CC1 4 , and 84 g (0.5 mole) of N-bromosuccinimide was refluxed for 6 hr. It was cooled and...34 4,5-Dinittoveratrole (A-82) k ~To a stirred mixture of 138 g (1.0 mole) of veratrole in 200 milq of AcOll at 150 was added 68 mil (96 g) of

  19. Design and experiment studies of a 2.6-MV diverter system

    NASA Astrophysics Data System (ADS)

    Hu, Yixiang; Zeng, Jiangtao; Jiang, Xiaofeng; Wang, Zhiguo; Liang, Tianxue; Qiu, Ai'ci

    2017-01-01

    Malfunctions of the Marx pre-fire or in the event that the main switch does not close were analyzed. Principles of the diverter system for protection of those events were introduced in detail. A 2.6 MV diverter system, consisting of an oil trigger switch and a Marx-coupled trigger generator, was developed. Based on "JianGuang-I" facility, a diverter-system test stand was established. And experiments with 2.3-MV working voltages were carried out to study the performance of this diverter system. Experiment results show that the time delay of this diverter system (from the beginning of the Marx erection to the time that the diverter-switch closes) is about 320 ns and its jitter (standard deviation) is about 8.9 ns. This diverter system has been tested more than 180 shots, and no problem has been encountered yet.

  20. Electrostatic surface structures of coal and mineral particles. Semi-annual report, September 1, 1996--March 1, 1997

    SciTech Connect

    Mazumder, M.K.; Lindquist, D.; Tennal, K.B.

    1997-12-31

    This paper contains three progress reports: Tribocharging Properties of Coal -- UV Photoelectron Spectroscopy by Adam Brown and Nick Grable; Electrostatic Separation of Coal as a Function of Particle Size Distribution by Jian Zheng; and Development of an Image Analyzer for Size and Charge Analysis of Coal Particles by Kevin Tennal and Gan Kok Hwee. The first paper discusses a literature survey and the instrumentation for photoelectron spectroscopy. The second discusses particle size classifying and electrodynamic trapping of charged particles. The third paper discusses laser and transmitting optics, collection optics, high voltage drives, electrodes, synchronization circuitry, camera, analysis of images, and additional considerations. An appendix to this paper describes the equations with the image analyzer.