Case 3. "Jiang Tao v. Chengdu Branch, People's People's Bank of China": Opinion by the People's Court in Wuhou District, Chengdu, Sichuan Province

ERIC Educational Resources Information Center

Chinese Education and Society, 2006

2006-01-01

This article presents the decision of the People's Court in Wuhou District, Chengdu, Sichuan Province on the Jiang Tao v. Chengdu Branch, People's People's Bank of China case. Jiang Tao, the plaintiff, claimed that the defendant Chengdu Branch placed an announcement in the "Chengdu Business Daily" to "recruit tellers for Chengdu…

LAN attack detection using Discrete Event Systems.

PubMed

Hubballi, Neminath; Biswas, Santosh; Roopa, S; Ratti, Ritesh; Nandi, Sukumar

2011-01-01

Address Resolution Protocol (ARP) is used for determining the link layer or Medium Access Control (MAC) address of a network host, given its Internet Layer (IP) or Network Layer address. ARP is a stateless protocol and any IP-MAC pairing sent by a host is accepted without verification. This weakness in the ARP may be exploited by malicious hosts in a Local Area Network (LAN) by spoofing IP-MAC pairs. Several schemes have been proposed in the literature to circumvent these attacks; however, these techniques either make IP-MAC pairing static, modify the existing ARP, patch operating systems of all the hosts etc. In this paper we propose a Discrete Event System (DES) approach for Intrusion Detection System (IDS) for LAN specific attacks which do not require any extra constraint like static IP-MAC, changing the ARP etc. A DES model is built for the LAN under both a normal and compromised (i.e., spoofed request/response) situation based on the sequences of ARP related packets. Sequences of ARP events in normal and spoofed scenarios are similar thereby rendering the same DES models for both the cases. To create different ARP events under normal and spoofed conditions the proposed technique uses active ARP probing. However, this probing adds extra ARP traffic in the LAN. Following that a DES detector is built to determine from observed ARP related events, whether the LAN is operating under a normal or compromised situation. The scheme also minimizes extra ARP traffic by probing the source IP-MAC pair of only those ARP packets which are yet to be determined as genuine/spoofed by the detector. Also, spoofed IP-MAC pairs determined by the detector are stored in tables to detect other LAN attacks triggered by spoofing namely, man-in-the-middle (MiTM), denial of service etc. The scheme is successfully validated in a test bed. Copyright © 2010 ISA. Published by Elsevier Ltd. All rights reserved.

Memory Consolidation of Attended Information Is Optional: Comment on Jiang et al. (2016)

ERIC Educational Resources Information Center

Wyble, Brad; Chen, Hui

2017-01-01

Attribute amnesia is a phenomenon in which information about a stimulus that was just recently used to perform a task is poorly remembered in a surprise test (Chen & Wyble, 2015a). In a recent article by Jiang, Shupe, Swallow, and Tan (2016), this effect was replicated but with an additional priming measure that revealed some carryover memory…

Multi-Protocol LAN Design and Implementation: A Case Study.

ERIC Educational Resources Information Center

Hazari, Sunil

1995-01-01

Reports on the installation of a local area network (LAN) at East Carolina University. Topics include designing the network; computer labs and electronic mail; Internet connectivity; LAN expenses; and recommendations on planning, equipment, administration, and training. A glossary of networking terms is also provided. (AEF)

"Reliability Of Fiber Optic Lans"

NASA Astrophysics Data System (ADS)

Code n, Michael; Scholl, Frederick; Hatfield, W. Bryan

1987-02-01

Fiber optic Local Area Network Systems are being used to interconnect increasing numbers of nodes. These nodes may include office computer peripherals and terminals, PBX switches, process control equipment and sensors, automated machine tools and robots, and military telemetry and communications equipment. The extensive shared base of capital resources in each system requires that the fiber optic LAN meet stringent reliability and maintainability requirements. These requirements are met by proper system design and by suitable manufacturing and quality procedures at all levels of a vertically integrated manufacturing operation. We will describe the reliability and maintainability of Codenoll's passive star based systems. These include LAN systems compatible with Ethernet (IEEE 802.3) and MAP (IEEE 802.4), and software compatible with IBM Token Ring (IEEE 802.5). No single point of failure exists in this system architecture.

Definitie Rapport Taktisch LAN Demonstratie (Definition Report Tactical LAN Demonstration)

DTIC Science & Technology

1990-06-01

am deze sneiheid te halen . Hierover kan eon uitspraak warden gedaan, enerzijds na de ontwikkeling van het S-4 interface en anderzijds na berokeningen...90-A02 *2ma~D. Definitie rapport taktisch LAN Niels Ult deze urgave reai erorden verrnengvldigd er of openbaar genakt door MiddeI van druk. folokopre...microfrilm Of OP wetke arroere 00lze 000 00k. zonoe, O~u S vdorafgaanoe loestermeng van TNOHet ter inzage gen van het TNO-rapport Ing. R. J . C.14

LAN Configuration and Analysis: Projects for the Data Communications and Networking Course

ERIC Educational Resources Information Center

Chen, Fang; Brabston, Mary

2011-01-01

We implemented two local area network (LAN) projects in our introductory data communications and networking course. The first project required students to develop a LAN from scratch for a small imaginary organization. The second project required student groups to analyze a LAN for a real world small organization. By allowing students to apply what…

Onychostoma brevibarba, a new cyprinine fish (Pisces: Teleostei) from the middle Chang Jiang basin in Hunan Province, South China.

PubMed

Song, Xue-Ling; Cao, Liang; Zhang, E

2018-04-16

Onychostoma brevibarba, a new cyprinid species, is described from two tributaries flowing into the Xiang Jiang (= River) of the middle Chang Jiang basin in Hunan Province, South China. The new species is morphologically similar to two Chinese congeners, O. minnanense and O. barbatulum, but differs from them in the anteromedian extension of the postlabial groove. It further differs from O. minnanense in the maxillary-barbel length, shape and body coloration, and from O. barbatulum in the number of lateral-line perforated scales and the width of the mouth opening. The validity of the new species and its close relationship with these two species were affirmed by a molecular phylogenetic analysis based on the mitochondrial cyt b and CO1 genes.

Expansion of the phosphatidylethanolamine binding protein family in legumes: a case study of Lupinus angustifolius L. FLOWERING LOCUS T homologs, LanFTc1 and LanFTc2.

PubMed

Książkiewicz, Michał; Rychel, Sandra; Nelson, Matthew N; Wyrwa, Katarzyna; Naganowska, Barbara; Wolko, Bogdan

2016-10-21

The Arabidopsis FLOWERING LOCUS T (FT) gene, a member of the phosphatidylethanolamine binding protein (PEBP) family, is a major controller of flowering in response to photoperiod, vernalization and light quality. In legumes, FT evolved into three, functionally diversified clades, FTa, FTb and FTc. A milestone achievement in narrow-leafed lupin (Lupinus angustifolius L.) domestication was the loss of vernalization responsiveness at the Ku locus. Recently, one of two existing L. angustifolius homologs of FTc, LanFTc1, was revealed to be the gene underlying Ku. It is the first recorded involvement of an FTc homologue in vernalization. The evolutionary basis of this phenomenon in lupin has not yet been deciphered. Bacterial artificial chromosome (BAC) clones carrying LanFTc1 and LanFTc2 genes were localized in different mitotic chromosomes and constituted sequence-specific landmarks for linkage groups NLL-10 and NLL-17. BAC-derived superscaffolds containing LanFTc genes revealed clear microsyntenic patterns to genome sequences of nine legume species. Superscaffold-1 carrying LanFTc1 aligned to regions encoding one or more FT-like genes whereas superscaffold-2 mapped to a region lacking such a homolog. Comparative mapping of the L. angustifolius genome assembly anchored to linkage map localized superscaffold-1 in the middle of a 15 cM conserved, collinear region. In contrast, superscaffold-2 was found at the edge of a 20 cM syntenic block containing highly disrupted collinearity at the LanFTc2 locus. 118 PEBP-family full-length homologs were identified in 10 legume genomes. Bayesian phylogenetic inference provided novel evidence supporting the hypothesis that whole-genome and tandem duplications contributed to expansion of PEBP-family genes in legumes. Duplicated genes were subjected to strong purifying selection. Promoter analysis of FT genes revealed no statistically significant sequence similarity between duplicated copies; only RE-alpha and CCAAT-box motifs were

Wireless Command-and-Control of UAV-Based Imaging LANs

NASA Technical Reports Server (NTRS)

Herwitz, Stanley; Dunagan, S. E.; Sullivan, D. V.; Slye, R. E.; Leung, J. G.; Johnson, L. F.

2006-01-01

Dual airborne imaging system networks were operated using a wireless line-of-sight telemetry system developed as part of a 2002 unmanned aerial vehicle (UAV) imaging mission over the USA s largest coffee plantation on the Hawaiian island of Kauai. A primary mission objective was the evaluation of commercial-off-the-shelf (COTS) 802.11b wireless technology for reduction of payload telemetry costs associated with UAV remote sensing missions. Predeployment tests with a conventional aircraft demonstrated successful wireless broadband connectivity between a rapidly moving airborne imaging local area network (LAN) and a fixed ground station LAN. Subsequently, two separate LANs with imaging payloads, packaged in exterior-mounted pressure pods attached to the underwing of NASA's Pathfinder-Plus UAV, were operated wirelessly by ground-based LANs over independent Ethernet bridges. Digital images were downlinked from the solar-powered aircraft at data rates of 2-6 megabits per second (Mbps) over a range of 6.5 9.5 km. An integrated wide area network enabled payload monitoring and control through the Internet from a range of ca. 4000 km during parts of the mission. The recent advent of 802.11g technology is expected to boost the system data rate by about a factor of five.

[Analysis of clinical characteristics of traditional Chinese and Western medicine in Professor Jiang Liangduo's theory of "sanjiao meridian stasis"].

PubMed

Wang, Hai-Yan; Jiang, Liang-Duo; Ma, Qing; Xu, Dong; Tang, Shi-Huan; Luo, Zeng-Gang

2017-12-01

In the clinical practice, Professor Jiang Liangduo, a national senior Chinese medicine doctor, has created the theory of "sanjiao meridian stasis" from the theory of meridian dialectics and from the overall state. In this paper, the traditional Chinese medicine and Western medicine clinical characteristics of sanjiao meridian stasis theory which is often used by Professor Jiang Liangduo in the treatment of out-patient syndrome differentiation, were first studied and summarized to investigate its inherent regularity. First, the source of data and research methods were introduced, and then the Traditional Chinese Medicine Inheritance Support System was used with the method of data mining to retrospectively analyze the disease characteristics of Chinese and Western medicine in 279 patients with sanjiao meridian stasis diagnosed by Professor Jiang in 2014. Then the following main conclusions were made after research: sanjiao meridian stasis was more common in women as well as young and middle-aged population. Often manifested by prolonged treatment course, red tongue with yellowishfur, with good correlation between modern Western medicine diagnosis and TCM differentiation syndrome. The symptoms of sanjiao meridian stasis syndrome are mostly of heat syndromes, and middle-aged patients are the most common patients with stasis and stasis of sanjiao. Related information of Western medicine diagnosis can help to diagnose the "sanjiao meridian stasis". Copyright© by the Chinese Pharmaceutical Association.

Identification of Bouc-Wen hysteretic parameters based on enhanced response sensitivity approach

NASA Astrophysics Data System (ADS)

Wang, Li; Lu, Zhong-Rong

2017-05-01

This paper aims to identify parameters of Bouc-Wen hysteretic model using time-domain measured data. It follows a general inverse identification procedure, that is, identifying model parameters is treated as an optimization problem with the nonlinear least squares objective function. Then, the enhanced response sensitivity approach, which has been shown convergent and proper for such kind of problems, is adopted to solve the optimization problem. Numerical tests are undertaken to verify the proposed identification approach.

Untargeted serum metabolomics reveals Fu-Zhu-Jiang-Tang tablet and its optimal combination improve an impaired glucose and lipid metabolism in type II diabetic rats.

PubMed

Tao, Yi; Chen, Xi; Cai, Hao; Li, Weidong; Cai, Baochang; Chai, Chuan; Di, Liuqing; Shi, Liyun; Hu, Lihong

2017-01-01

Fu-Zhu-Jiang-Tang tablet, a six-herb preparation, was proved to show beneficial effects on type II diabetes patients in clinical. This study aims to optimize the component proportion of the six-herb preparation and explore the serum metabolic signatures of type II diabetes rats after treatment with Fu-Zhu-Jiang-Tang tablet and its optimal combination. The component proportion of the preparation was optimized using uniform experimental design and machine learning techniques. Untargeted GC-MS metabolomic experiments were carried out with serum samples from model group and treatment groups. Data were normalized, multivariate and univariate statistical analysis performed and metabolites of interest putatively identified. 23 metabolites were significantly changed by Fu-Zhu-Jiang-Tang tablet treatment and the majority of these were decreased, including various carbohydrates (glucose, mannose, fructose, allose and gluconic acid), unsaturated fatty acids (palmitic acid, 9-octadecenoic acid, oleic acid, arachidonic acid), alanine, valine, propanoic acid, 3-hydroxybutyrate, along with pyrimidine and cholesterol. Increased concentrations of oxalic acid, leucine, glycine, serine, threonine, proline, lysine and citrate were observed. In the optimal combination-fed group, 21 metabolites were significantly affected and strikingly, the magnitudes of changes here were generally much greater than that of Fu-Zhu-Jiang-Tang tablet treated rats. 18 metabolites affected in both groups included various carbohydrates (mannose, glucose, allose, fructose and gluconic acid), unsaturated fatty acids (palmitic acid, 9-octadecenoic acid, oleic acid and arachidonic acid), short-chain fatty acids (oxalic acid, 3-hydroxybutyrate), and amino acids (alanine, valine, leucine, glycine, proline and lysine), as well as pyrimidine. Metabolites exclusively affected in optimal combination treated rat included succinic acid, cysteine and phenylalanine, whilst four metabolites (propanoic acid, citrate

Video and LAN solutions for a digital OR: the Varese experience

NASA Astrophysics Data System (ADS)

Nocco, Umberto; Cocozza, Eugenio; Sivo, Monica; Peta, Giancarlo

2007-03-01

Purpose: build 20 ORs equipped with independent video acquisition and broadcasting systems and a powerful LAN connectivity. Methods: a digital PC controlled video matrix has been installed in each OR. The LAN connectivity has been developed to grant data entering the OR and high speed connectivity to a server and to broadcasting devices. Video signals are broadcasted within the OR. Fixed inputs and five additional video inputs have been placed in the OR. Images can be stored locally on a high capacity HDD and a DVD recorder. Images can be also stored in a central archive for future acquisition and reference. Ethernet plugs have been placed within the OR to acquire images and data from the Hospital LAN; the OR is connected to the server/archive using a dedicated optical fiber. Results: 20 independent digital ORs have been built. Each OR is "self contained" and images can be digitally managed and broadcasted. Security issues concerning both image visualization and electrical safety have been fulfilled and each OR is fully integrated in the Hospital LAN. Conclusions: Digital ORs were fully implemented, they fulfill surgeons needs in terms of video acquisition and distribution and grant high quality video for each kind of surgery in a major hospital.

Local Area Network (LAN) Compatibility Issues

DTIC Science & Technology

1991-09-01

September, 1991 Thesis Advisor: Dr. Norman Schneidewind Approved for public release; distribution is unlimited 92 303s246 Unclassified SECURITY ...CLASSIFICATION OF THIS PAGE REPORT DOCUMENTATION PAGE Ia. REPORT SECURITY CLASSIFICATION 1 b. RESTRICTIVE MARKINGS unclassified 2a. SECURITY CLASSIFICATION...Work UiNt ACCeLUOn Number 11. TITLE (Include Security Classification) LOCAL AREA NETWORK (LAN) COMPATIBILITY ISSUES 12. PERSONAL AUTHOR(S) Rita V

[Physiology of the pi in Su Wen and Ling Shu in comparison with the spleen in Dutch medicine].

PubMed

Endō, J; Nakamura, T

1992-12-01

The physiological function of the pi (translated in English as spleen) in traditional Chinese medicine is generally known as the promotion of digestion. But the concept of pi has changed with the times. According to the Su Wen and the Ling Shy, the pi does not directly take part in digestion. These writings often describe the pi as the "pi merdian", considered to contribute to the function of the circulatory system. Comparing the descriptions of the pi in Su Wen and Ling Shu with those of the spleen in Dutch medical books published in the Edo period, we found the following similarities between these two different kinds of medical concepts. Both the pi in the former and the spleen in the latter are considered to be important in transportation of lymph. Furthermore, the pi meridian and jinye (body fluid) in the former correspond to the lymphatic vessel and lymph in the latter, respectively. ...

All-optical LAN architectures based on arrayed waveguide grating multiplexers

NASA Astrophysics Data System (ADS)

Woesner, Hagen

1998-10-01

The paper presents optical LAN topologies which are made possible using an Arrayed Waveguide Grating Multiplexer (AWGM) instead of a passive star coupler to interconnect stations in an all-optical LAN. Due to the collision-free nature of an AWGM it offers the n-fold bandwidth compared to the star coupler. Virtual ring topologies appear (one ring on each wavelength) if the number of stations attached to the AWGM is a prime number. A method to construct larger networks using Cayley graphs is shown. An access protocol to avoid collisions on the proposed network is outlined.

Species classification and bioactive ingredients accumulation of BaiJiangCao based on characteristic inorganic elements analysis by inductively coupled plasma-mass spectrometry and multivariate analysis

PubMed Central

Wen-Lan, Li; Xue, Zhang; Xin-Xin, Yang; Shuai, Wang; Lin, Zhao; Huan-Jun, Zhao; Yong-Rui, Bao; Chen-Feng, Ji; Ning, Chen; Zheng, Xiang

2015-01-01

Background: Patrinia scabiosaefolia Fisch and Patrinia villosa (Thunb.) Juss., two species herbs with the same Chinese name “BaiJiangCao”, are important ancient herbal medicines widely used for more than 2000 years. The clinical application of two species herb is confused due to the difficult identification. Objective: The objective was to authenticate the species of BaiJiangCao and analyze the accumulation of bioactive ingredients based on characteristic inorganic elements analysis. Materials and Methods: Content of 32 inorganic elements in BaiJiangCao from different habitats were determined by inductively coupled plasma-mass spectrometry (ICP-MS), and the characteristic inorganic elements were picked to distinguish the species of the herb by principal component analysis and cluster analysis. Contents of two bioactive ingredients, luteoloside, and oleanolic acid, in the samples, were also analyzed by high-performance liquid chromatography method. Relationship between accumulation of bioactive ingredients and content of macroelements in BaiJiangCao was established by statistics. Results: A 4 macroelements (Na, Mg, K, Fe) in 32 determined inorganic elements were picked for characteristic inorganic elements. Content of Na, Mg, K and Fe showed positive correlations with that of luteoloside, content of Na, Mg showed positive correlations with that of oleanolic acid, but content of K and Fe showed negative correlations with that of oleanolic acid. Conclusion: It is for the first time to utilize the characteristic inorganic elements as an index to classify the herb species by the method of ICP-MS and multivariate analysis. And it is also the first report to investigate the influence of inorganic elements in herb on the accumulation of bioactive components which could affect the pharmacological efficacy of the herb medicine. And this method could also be utilized in research of corresponding aspects. PMID:26600721

The List of Available Names (LAN): A new generation for stable taxonomic names in zoology?

PubMed

Alonso-Zarazaga, Miguel A; Fautin, Daphne Gail; Michel, Ellinor

2016-01-01

The List of Available Names in Zoology (LAN) is an inventory of names with specific scope in time and content, presented and approved in parts, and constituted as a cumulative index of names available for use in zoological nomenclature. It was defined in Article 79 in the fourth edition of the International Code of Zoological Nomenclature. The LAN is likely to gain importance with the development of the online Official Registry for Zoological Nomenclature (ZooBank) as it is potentially a source of many nomenclaturally certified names. Article 79 describes the deliberative process for adding large numbers of names to the LAN simultaneously, detailing steps and chronology for submission of a candidate Part to the LAN and consideration of a candidate Part by the public and Commission, but it is largely mute about the contents of a candidate Part. It does make clear that a name within the scope of a Part but not on the LAN has no nomenclatural standing, even if it had previously been considered available, thereby preventing long-forgotten names from displacing accepted ones and the accumulation of nomina dubia. Thus, for taxa on the LAN, nomenclatural archaeology - the resurrecting of old unused names to replace by priority names in current usage - will not be worthwhile. Beyond that, it has been unclear if Article 79 is intended to document every available name known within the scope of the Part, or if its intention is to pare the inventory of available names within the scope of the Part. Consideration by the Commission and two committees to deal with the LAN have defined steps to implement Article 79 with the latter intent. Procedures for consideration of a candidate Part are defined in a manual, published as an appendix in this volume.

[Analyze prescription rules of Professor Jiang Liangduo treatment for abdominal mass based on traditional Chinese medicine inheritance platform].

PubMed

Lian, Xiao-Xiao; Guo, Xiao-Xia

2018-01-01

To investigate the herbal prescription rules of Professor Jiang Liangduo in the treatment of abdominal mass based on the traditional Chinese medicine inheritance support system software (TCMISS) of version 2.5, find out new herbal formulas for the treatment of abdominal mass, and then provide new reference to its traditional Chinese medicine therapy. By the method of retrospective study, one hundred and thirty-two outpatient prescriptions of Professor Jiang for the treatment of abdominal mass were collected to establish a typical database with TCMISS. Four properties, five tastes, channel tropism, frequency count, Chinese herbal prescriptions rules and the new prescriptions were analyzed so as to dig out the prescription rules. There were 57 herbs with a frequency>=15, and then 91 core combinations of 2-5 herbs were evolved and 9 new prescriptions were created. It was found out that these drugs mainly had the effects of liver nourishing and soothing, soft-moist and dredging-tonifying, supporting right and dispeling evil, cooperating with the method of calming the liver and resolving hard lump according to the actual situation. It reflected the thought of treatment based on syndrome differentiation in TCM, and provided a new reference for its clinical treatment and research. Copyright© by the Chinese Pharmaceutical Association.

LAN MAP: An Innovative Airborne Light at Night Mapping Project

NASA Astrophysics Data System (ADS)

Craine, Eric R.; Craine, B. L.; Craine, E. M.; Craine, P. R.

2013-01-01

Widespread installation of inefficient and misdirected artificial light at night (LAN) has led to increasing concerns about light pollution and its impact, not only on astronomical facilities but larger communities as well. Light pollution impacts scientific research, environmental ecosystems, human health, and quality of life. In recent years, the public policy response to light pollution has included formulation of government codes to regulate lighting design and installation. Various environmental groups now include light pollution among their rallying themes to protest both specific and general developments. The latter efforts are often conducted in the absence of any quantitative data and are frequently charged by emotion rather than reason. To bring some scientific objectivity, and quantitative data, to these discussions, we have developed a suite of tools for simultaneous photometric measurements and temporal monitoring of both local communities and the sky overhead. We have also developed novel protocols for the use of these tools, including a triad of airborne, ground mobile, and ground static photometric surveys. We present a summary of these tools and protocols, with special emphasis on the airborne systems, and discuss baseline and follow-up measurements of LAN environments in the vicinity of numerous observatories in Arizona, the home of the initial LAN MAP surveys.

Consideration of IP Telephony Quality on the IEEE802.11a Wireless LAN

NASA Astrophysics Data System (ADS)

Miyashita, Michifumi; Takamatsu, Hideyuki; Kurono, Masahiro

Recently, IP telephony services in wired network are started, and paid attention for its charge-free nature due to IP technology. On the other hand, the Hot-Spot service, which provides one to access the Internet at the public space such as cafe, using the IEEE wireless LAN has been evolved, and it is expected that the IP telephony service on the Hot-Spot network will be developed. However, the IP telephony quality on the IEEE802.11a wireless LAN has not been fully studied yet. In this paper, we discuss about the quality of IP telephony service on the IEEE802.11a wireless LAN from the aspect of R-value, and show ability to improve the IP telephony quality on the Hot-Spot network employing PLC function defined in the ITU-T Recommendation G.711 Appendix I.

Straight talk with... Tom Inglesby. Interview by Kevin Jiang.

PubMed

Inglesby, Tom

2013-06-01

When letters containing anthrax spores were mailed to several US senators and media offices in September 2001, just one week after the 9/11 attacks, bioterrorism catapulted to the national stage. Political leaders and public health officials, desperate for guidance on this once-theoretical scenario, turned to experts including Tom Inglesby, then deputy director of the Johns Hopkins Center for Civilian Biodefense Strategies, a bioterrorism research and analysis think tank in Baltimore. In the years that followed, Inglesby and his colleagues ran exercises to simulate bioterror incidents, established a peer-reviewed journal on biodefense and advised government agencies on how to reduce the public health impact of biological threats.Today, he continues his work with the think tank, which moved to the University of Pittsburgh Medical Center (UPMC) in 2003 (although it stayed headquartered in Baltimore) and which was recently renamed the UPMC Center for Health Security. As director and chief executive officer for the past four years, Inglesby has expanded the center's focus toward preventing public health crises arising from infectious diseases, pandemics and major natural disasters, in addition to biological, chemical and nuclear accidents or threats. Inglesby spoke with Kevin Jiang about how responses to bioterrorism, pandemics and natural disasters aren't all that different.

Networking the Light Fantastic--CD-ROMs on LANs.

ERIC Educational Resources Information Center

Kittle, Paul W.

1992-01-01

Describes the development of a local area network (LAN) at Loma Linda University that allows remote access for both IBM and Macintosh microcomputers to CD-ROMs. Topics discussed include types of networks; fiber optic technology; networking CD-ROM drives; remote access; modems; CD-ROM databases; memory management; interface software; and future…

The UNIX Operating System in Libraries: Advantages of LAN's and Bulletin Board Systems in Your Library.

ERIC Educational Resources Information Center

Rose, Phillip E.

1988-01-01

Describes the experiences of the AT&T Technical Library in installing a local area network (LAN) and bulletin board using the UNIX operating system. Reasons why a LAN was needed, how the system works, and hardware and software used are discussed. (1 reference) (MES)

Ecological Impact of LAN: San Pedro Riparian National Conservation Area

NASA Astrophysics Data System (ADS)

Craine, Eric Richard; Craine, Brian L.

2015-08-01

The San Pedro River in Southeastern Arizona is home to nearly 45% of the 900 total species of birds in the United States; millions of songbirds migrate though this unique flyway every year. As the last undammed river in the Southwest, it has been called one of the “last great places” in the US. Human activity has had striking and highly visible impacts on the San Pedro River. As a result, and to help preserve and conserve the area, much of the region has been designated the San Pedro Riparian National Conservation Area (SPRNCA). Attention has been directed to impacts of population, water depletion, and border fence barriers on the riparian environment. To date, there has been little recognition that light at night (LAN), evolving with the increased local population, could have moderating influences on the area. STEM Laboratory has pioneered techniques of coordinated airborne and ground based measurements of light at night, and has undertaken a program of characterizing LAN in this region. We conducted the first aerial baseline surveys of sky brightness in 2012. Geographic Information Systems (GIS) shapefiles allow comparison and correlation of various biological databases with the LAN data. The goal is to better understand how increased dissemination of night time lighting impacts the distributions, behavior, and life cycles of biota on this ecosystem. We discuss the baseline measurements, current data collection programs, and some of the implications for specific biological systems.

Wireless LAN security management with location detection capability in hospitals.

PubMed

Tanaka, K; Atarashi, H; Yamaguchi, I; Watanabe, H; Yamamoto, R; Ohe, K

2012-01-01

In medical institutions, unauthorized access points and terminals obstruct the stable operation of a large-scale wireless local area network (LAN) system. By establishing a real-time monitoring method to detect such unauthorized wireless devices, we can improve the efficiency of security management. We detected unauthorized wireless devices by using a centralized wireless LAN system and a location detection system at 370 access points at the University of Tokyo Hospital. By storing the detected radio signal strength and location information in a database, we evaluated the risk level from the detection history. We also evaluated the location detection performance in our hospital ward using Wi-Fi tags. The presence of electric waves outside the hospital and those emitted from portable game machines with wireless communication capability was confirmed from the detection result. The location detection performance showed an error margin of approximately 4 m in detection accuracy and approximately 5% in false detection. Therefore, it was effective to consider the radio signal strength as both an index of likelihood at the detection location and an index for the level of risk. We determined the location of wireless devices with high accuracy by filtering the detection results on the basis of radio signal strength and detection history. Results of this study showed that it would be effective to use the developed location database containing radio signal strength and detection history for security management of wireless LAN systems and more general-purpose location detection applications.

Taxonomy of Macromotettixoides with the description of a new species (Tetrigidae, Metrodorinae)

PubMed Central

Zha, Ling-Sheng; Yu, Feng-Ming; Boonmee, Saranyaphat; Eungwanichayapant, Prapassorn D.; Wen, Ting-Chi

2017-01-01

Abstract Descriptions of the flying organs and generic characteristics of the genus Macromotettixoides Zheng, Wei & Jiang are currently imprecise. Macromotettixoides is reviewed and compared with allied genera. A re-description is undertaken and a determination key is provided to Macromotettixoides. Macromotettixoides parvula Zha & Wen, sp. n. from the Guizhou Karst Region, China, is described and illustrated with photographs. Observations on the ecology and habits of the new species are recorded. Four current species of Hyboella Hancock are transferred to Macromotettixoides. Variations of the flying organs and tegminal sinus in the Tetrigidae are discussed, which will help to describe them accurately. PMID:28228664

Infrared transmission of electronic information via LAN in the operating room.

PubMed

Hagihira, S; Takashina, M; Mori, T; Taenaka, N; Mashimo, T; Yoshiya, I

2000-01-01

Recent advances in technology have brought many kinds of monitoring devices into the operating room (OR). The information gathered by monitors can be channeled to the operating ward information system via a local area network (LAN). Connecting patients to monitors and monitors to the LAN, however, requires a large number of cables. This wiring is generally inconvenient and particularly troublesome if the layout of the OR is rearranged. From this point of view, wireless transmission seems ideally suited to clinical settings. Currently, two modes of wireless connectivity are available: radio-frequency (RF) waves or infrared (IR) waves. Some reports suggest that RF transmission is likely to cause electromagnetic interference (EMI) in medical devices such as cardiac pacemakers or infusion pumps. The risk of malfunctioning life-sustaining devices and the catastrophic consequences this would have on seriously ill patients rules out the use of RF. Here, we report an IR system using IR modems for LAN connectivity in the OR. In this study, we focused on the possible detrimental effects of EMI during wireless connectivity. In our trial, we found no evidence of EMI of IR modems with any of the medical devices we tested. Furthermore, IR modems showed similar performance to a wired system even in an electrically noisy environment. We conclude that IR wireless connectivity can be safely and effectively used in ORs.

LAN (Local Area Network) Interoperability Study of Protocols Needed for Distributed Command and Control

DTIC Science & Technology

1985-03-01

model referred to by the study group . IMCKIiN cuINICATION 31215FOR SDATA TWSU•l Sa *BSTtEO POOTO• AA14FTICT’WI PEM1 ITS ...operating systems, compared the DOD and ISO networking protocol architecture models , the protocols for LAN’s developed by the IEEE and ANSI, reviewed and...be initiated, so as to provide the Air Force a roadmap to guide its * "technology develop •ents. 4,’ �/LAN 3-4 .°. SECTION 4.0

Interview with Datin Goh Suet Lan on Business Coaching

ERIC Educational Resources Information Center

Nimehchisalem, Vahid

2016-01-01

In this article the author writes of having had the pleasure of meeting Datin Goh Suet Lan and one of the key members of her team, Mr. Murali, in the Faculty of Modern Languages and Communication, Universiti Putra Malaysia with three colleagues, Associate Professor Dr. Shamala Paramasivam (who initiated this meeting), Dr. Ilyana Binti Jalaluddin,…

VPLS: an effective technology for building scalable transparent LAN services

NASA Astrophysics Data System (ADS)

Dong, Ximing; Yu, Shaohua

2005-02-01

Virtual Private LAN Service (VPLS) is generating considerable interest with enterprises and service providers as it offers multipoint transparent LAN service (TLS) over MPLS networks. This paper describes an effective technology - VPLS, which links virtual switch instances (VSIs) through MPLS to form an emulated Ethernet switch and build Scalable Transparent Lan Services. It first focuses on the architecture of VPLS with Ethernet bridging technique at the edge and MPLS at the core, then it tries to elucidate the data forwarding mechanism within VPLS domain, including learning and aging MAC addresses on a per LSP basis, flooding of unknown frames and replication for unknown, multicast, and broadcast frames. The loop-avoidance mechanism, known as split horizon forwarding, is also analyzed. Another important aspect of VPLS service is its basic operation, including autodiscovery and signaling, is discussed. From the perspective of efficiency and scalability the paper compares two important signaling mechanism, BGP and LDP, which are used to set up a PW between the PEs and bind the PWs to a particular VSI. With the extension of VPLS and the increase of full mesh of PWs between PE devices (n*(n-1)/2 PWs in all, a n2 complete problem), VPLS instance could have a large number of remote PE associations, resulting in an inefficient use of network bandwidth and system resources as the ingress PE has to replicate each frame and append MPLS labels for remote PE. So the latter part of this paper focuses on the scalability issue: the Hierarchical VPLS. Within the architecture of HVPLS, this paper addresses two ways to cope with a possibly large number of MAC addresses, which make VPLS operate more efficiently.

Providing Access to CD-ROM Databases in a Campus Setting. Part II: Networking CD-ROMs via a LAN.

ERIC Educational Resources Information Center

Koren, Judy

1992-01-01

The second part of a report on CD-ROM networking in libraries describes LAN (local area network) technology; networking software and towers; gateway software for connecting to campuswide networks; Macintosh LANs; and network licenses. Several product and software reviews are included, and a sidebar lists vendor addresses. (NRP)

Ensuring the security and availability of a hospital wireless LAN system.

PubMed

Hanada, Eisuke; Kudou, Takato; Tsumoto, Shusaku

2013-01-01

Wireless technologies as part of the data communication infrastructure of modern hospitals are being rapidly introduced. Even though there are concerns about problems associated with wireless communication security, the demand is remarkably large. Herein we discuss security countermeasures that must be taken and issues concerning availability that must be considered to ensure safe hospital/business use of wireless LAN systems, referring to the procedures introduced at a university hospital. Security countermeasures differ according to their purpose, such as preventing illegal use or ensuring availability, both of which are discussed. The main focus of the availability discussion is on signal reach, electromagnetic noise elimination, and maintaining power supply to the network apparatus. It is our hope that this information will assist others in their efforts to ensure safe implementation of wireless LAN systems, especially in hospitals where they have the potential to greatly improve information sharing and patient safety.

Indirubin, a component of Ban-Lan-Gen, activates CYP3A4 gene transcription through the human pregnane X receptor.

PubMed

Kumagai, Takeshi; Aratsu, Yusuke; Sugawara, Ryosuke; Sasaki, Takamitsu; Miyairi, Shinichi; Nagata, Kiyoshi

2016-04-01

Ban-Lan-Gen is the common name for the dried roots of indigo plants, including Polygonum tinctorium, Isatis indigotica, Isatis tinctoria, and Strobilanthes cusia. Ban-Lan-Gen is frequently used as an anti-inflammatory and an anti-viral for the treatment of hepatitis, influenza, and various types of inflammation. One of the cytochrome P450 (CYP) enzymes, CYP3A4, is responsible for the metabolism of a wide variety of xenobiotics, including an estimated 60% of all clinically used drugs. In this study, we investigated the effect of Ban-Lan-Gen on the transcriptional activation of the CYP3A4 gene. Ban-Lan-Gen extract increased CYP3A4 gene reporter activity in a dose-dependent manner. Indirubin, one of the biologically active ingredients in the Ban-Lan-Gen, also dose-dependently increased CYP3A4 gene reporter activity. Expression of short hairpin RNA for the human pregnane X receptor (hPXR-shRNA) inhibited CYP3A4 gene reporter activity, and overexpression of human PXR increased indirubin- and rifampicin-induced CYP3A4 gene reporter activity. Furthermore, indirubin induced CYP3A4 mRNA expression in HepG2 cells. Taken together, these results indicate that indirubin, a component of Ban-Lan-Gen, activated CYP3A4 gene transcription through the activation of the human PXR. Copyright © 2016. Published by Elsevier Ltd.

Structural characterization of O- and C-glycosylating variants of the landomycin glycosyltransferase LanGT2.

PubMed

Tam, Heng Keat; Härle, Johannes; Gerhardt, Stefan; Rohr, Jürgen; Wang, Guojun; Thorson, Jon S; Bigot, Aurélien; Lutterbeck, Monika; Seiche, Wolfgang; Breit, Bernhard; Bechthold, Andreas; Einsle, Oliver

2015-02-23

The structures of the O-glycosyltransferase LanGT2 and the engineered, C-C bond-forming variant LanGT2S8Ac show how the replacement of a single loop can change the functionality of the enzyme. Crystal structures of the enzymes in complex with a nonhydrolyzable nucleotide-sugar analogue revealed that there is a conformational transition to create the binding sites for the aglycon substrate. This induced-fit transition was explored by molecular docking experiments with various aglycon substrates. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

[Li Wen-Rong's experience on acupuncture at painful locality taken as acupoint].

PubMed

Wei, Qing-Lin; Li, Jun

2010-04-01

Doctor Li Wen-Rong, who has been practicing acupuncture for five decades by combination of the meridian theory of TCM and related modern medical science, has still been active in acupuncture clinic, especially in acupuncture manipulation based on the method of acupuncture at painful locality taken as acupoint, Jiaji (EX-B 2) being selected as the main acupoints and Back-shu acupoints of the Bladder Meridian as adjuvant acupoints, except the acupoints on the limbs, and the selected acupoints being relatively concentrated and the needles being inserted in tender points for treatment of relevant nervous system diseases and complicated chronic cases, which has formed her own academic style. In this article, the authors introduce some of her medical records by using acupuncture manipulation based on the method of acupuncture at painful locality taken as acupoint for treatment of facial paralysis, renal colic and rheumatoid arthritis, and the main idea of this article is to summarize and analyze her academic thoughts.

Full dyon excitation spectrum in extended Levin-Wen models

NASA Astrophysics Data System (ADS)

Hu, Yuting; Geer, Nathan; Wu, Yong-Shi

2018-05-01

In Levin-Wen (LW) models, a wide class of exactly solvable discrete models, for two-dimensional topological phases, it is relatively easy to describe only single-fluxon excitations, but not the charge and dyonic as well as many-fluxon excitations. To incorporate charged and dyonic excitations in (doubled) topological phases, an extension of the LW models is proposed in this paper. We first enlarge the Hilbert space with adding a tail on one of the edges of each trivalent vertex to describe the internal charge degrees of freedom at the vertex. Then, we study the full dyon spectrum of the extended LW models, including both quantum numbers and wave functions for dyonic quasiparticle excitations. The local operators associated with the dyonic excitations are shown to form the so-called tube algebra, whose representations (modules) form the quantum double (categoric center) of the input data (unitary fusion category). In physically relevant cases, the input data are from a finite or quantum group (with braiding R matrices), and we find that the elementary excitations (or dyon species), as well as any localized/isolated excited states, are characterized by three quantum numbers: charge, fluxon type, and twist. They provide a "complete basis" for many-body states in the enlarged Hilbert space. Concrete examples are presented and the relevance of our results to the electric-magnetic duality existing in the models is addressed.

Performance analysis of LAN bridges and routers

NASA Technical Reports Server (NTRS)

Hajare, Ankur R.

1991-01-01

Bridges and routers are used to interconnect Local Area Networks (LANs). The performance of these devices is important since they can become bottlenecks in large multi-segment networks. Performance metrics and test methodology for bridges and routers were not standardized. Performance data reported by vendors is not applicable to the actual scenarios encountered in an operational network. However, vendor-provided data can be used to calibrate models of bridges and routers that, along with other models, yield performance data for a network. Several tools are available for modeling bridges and routers - Network II.5 was used. The results of the analysis of some bridges and routers are presented.

The TurboLAN project. Phase 1: Protocol choices for high speed local area networks. Phase 2: TurboLAN Intelligent Network Adapter Card, (TINAC) architecture

NASA Technical Reports Server (NTRS)

Alkhatib, Hasan S.

1991-01-01

The hardware and the software architecture of the TurboLAN Intelligent Network Adapter Card (TINAC) are described. A high level as well as detailed treatment of the workings of various components of the TINAC are presented. The TINAC is divided into the following four major functional units: (1) the network access unit (NAU); (2) the buffer management unit; (3) the host interface unit; and (4) the node processor unit.

Security Engineering Lessons Learned for Migrating Independent LANs to an Enterprise Environment

ERIC Educational Resources Information Center

Marchant, Robert L.; Bonneau, Thomas

2013-01-01

Transition from small, independent LANs into larger enterprise managed infrastructures is becoming more prominent in academia, business and government. Consolidation of IT resources into larger, more disciplined, and more professionally managed environments has significant advantages however they do bring their own unique issues to solve in order…

Comparison of Ga-68 DOTA-TATE and Ga-68 DOTA-LAN PET/CT imaging in the same patient group with neuroendocrine tumours: preliminary results.

PubMed

Demirci, Emre; Ocak, Meltem; Kabasakal, Levent; Araman, Ahmet; Ozsoy, Yildiz; Kanmaz, Bedii

2013-08-01

Recent studies have suggested that PET imaging with Ga-68-labelled DOTA-somatostatin analogues such as octreotide and octreotate is useful in diagnosing neuroendocrine tumours (NETs) and has superior value over both computed tomography and planar and SPECT somatostatin receptor scintigraphy. The aim of the present study was to evaluate the role of Ga-68 DOTA-lanreotide (Ga-68-DOTA-LAN) in patients with somatostatin receptor (sst)-expressing tumours and to compare the results of Ga-68 DOTA-D-Phe1-Tyr3-octreotate (Ga-68-DOTA-TATE) in the same patient population. Twelve patients with NETs who were referred to our department for somatostatin receptor scintigraphy were included in the study. There were four patients with well-differentiated neuroendocrine tumour (WDNET) grade 1, two patients with WDNET grade 2, and three patients with poorly differentiated neuroendocrine carcinoma (PDNEC) grade 3. There was also one patient with medullary thyroid cancer, one patient with meningioma and one patient with MEN-1. All patients underwent two consecutive PET imaging studies with Ga-68-DOTA-TATE and Ga-68 DOTA-LAN. All images were evaluated visually, and maximum standardized uptake value was calculated for quantitative evaluation. On visual examination of maximum intensity projection images, GA-68 DOTA-LAN was seen to have high background activity and high bone marrow uptake. Both tracers defined 67 lesions. Ga-68 DOTA-TATE images revealed 63 (94%) clearly defined lesions, missing four lesions. In contrast, Ga-68 DOTA-LAN images defined only 23 (44%) lesions, missing 44 (56%) lesions. Thirty-two bone lesions were detected on Ga-68-DOTA-TATE images. Among them, only 11 (34%) were positive on Ga-68 DOTA-LAN images, whereas 21 (66%) were negative. When we evaluated liver, mediastinum and gastrointestinal tract lesions, Ga-68 DOTA-LAN was seen to be positive for 12 (34%) lesions and negative for 23 (66%) lesions. Although the results are preliminary, the image quality obtained by

Access Point Selection for Multi-Rate IEEE 802.11 Wireless LANs

DTIC Science & Technology

2014-05-16

Mobile Systems, Applications and Services, 2006. [2] S . Vasudevan, K. Papagiannaki, C . Diot, J. Kurose, and D. Towsley, “Facilitating Access Point...LANs 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR( S ) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7...PERFORMING ORGANIZATION NAME( S ) AND ADDRESS(ES) University of California at Berkeley,Electrical Engineering and Computer Sciences,Berkeley,CA,94720 8

Sensitivity Studies of 3D Reservoir Simulation at the I-Lan Geothermal Area in Taiwan Using TOUGH2

NASA Astrophysics Data System (ADS)

Kuo, C. W.; Song, S. R.

2014-12-01

A large scale geothermal project conducted by National Science Council is initiated recently in I-Lan south area, northeastern Taiwan. The goal of this national project is to generate at least 5 MW electricity from geothermal energy. To achieve this goal, an integrated team which consists of various specialties are held together to investigate I-Lan area comprehensively. For example, I-Lan geological data, petrophysical analysis, seismicity, temperature distribution, hydrology, geochemistry, heat source study etc. were performed to build a large scale 3D conceptual model of the geothermal potential sites. In addition, not only a well of 3000m deep but also several shallow wells are currently drilling to give us accurate information about the deep underground. According to the current conceptual model, the target area is bounded by two main faults, Jiaosi and Choshui faults. The geothermal gradient measured at one drilling well (1200m) is about 49.1˚C/km. The geothermal reservoir is expected to occur at a fractured geological formation, Siling sandstone layer. The preliminary results of this area from all the investigations are used as input parameters to create a realistic numerical reservoir model. This work is using numerical simulator TOUGH2/EOS1 to study the geothermal energy potential in I-Lan area. Once we can successfully predict the geothermal energy potential in this area and generate 5 MW electricity, we can apply the similar methodology to the other potential sites in Taiwan, and therefore increase the percentage of renewable energy in the generation of electricity. A large scale of three-dimensional subsurface geological model is built mainly based on the seismic exploration of the subsurface structure and well log data. The dimensions of the reservoir model in x, y, and z coordinates are 20x10x5 km, respectively. Once the conceptual model and the well locations are set up appropriately based on the field data, sensitivity studies on production and

Installation of secure, always available wireless LAN systems as a component of the hospital communication infrastructure.

PubMed

Hanada, Eisuke; Kudou, Takato; Tsumoto, Shusaku

2013-06-01

Wireless technologies as part of the data communication infrastructure of modern hospitals are being rapidly introduced. Even though there are concerns about problems associated with wireless communication security, the demand is remarkably large. In addition, insuring that the network is always available is important. Herein, we discuss security countermeasures and points to insure availability that must be taken to insure safe hospital/business use of wireless LAN systems, referring to the procedures introduced at Shimane University Hospital. Security countermeasures differ according to their purpose, such as for preventing illegal use or insuring availability, both of which are discussed. It is our hope that this information will assist others in their efforts to insure safe implementation of wireless LAN systems, especially in hospitals where they have the potential to greatly improve information sharing and patient safety.

Origin of stratiform sediment-hosted manganese carbonate ore deposits: Examples from Molango, Mexico, and TaoJiang, China

USGS Publications Warehouse

Okita, P.M.; Shanks, Wayne C.

1992-01-01

Carbonate and sulfide minerals from the Molango, Mexico, and TaoJiang, China, Mn deposits display similar and distinctive ??34S and ??13C patterns in intervals of manganese carbonate mineralization. ??13C-values for Mn-bearing carbonate range from -17.8 to +0.5??? (PDB), with the most negative values occurring in high-grade ore zones that are composed predominantly of rhodochrosite. In contrast, calcite from below, within and above Mn-carbonate zones at Molango has ??13C???0??? (PDB). Markedly negative ??13C data indicate that a large proportion of the carbon in Mn-carbonates was derived from organic matter oxidation. Diagenetic reactions using MnO2 and SO2-4 to oxidize sedimentary organic matter were the principle causes of such 12C enrichment. Pyrite content and sulfide ?? 34S-values also show distinctive variations. In unmineralized rocks, very negative ??34S-values (avg. < -21??? CDT) and abundant pyrite content suggest that pyrite formed from diagenetic, bacteriogenic sulfate reduction. In contrast, Mn-bearing horizons typically contain only trace amounts of pyrite (e.g., <0.5 wt% S with ??34S-values 34S-enriched, in some cases to nearly the value for contemporaneous seawater. 34S-enriched pyrite from the Mn-carbonate intervals indicates sulfide precipitation in an environment that underwent extensive SO2-4 reduction, and was largely a closed system with regard to exchange of sulfate and dissolved sulfide with normal seawater. The occasional occurrence of 34S-depleted pyrite within Mn-carbonate zones dominated by 34S-enriched pyrite is evidence that closed-system conditions were intermittent and limited to local pore waters and did not involve entire sedimentary basins. Mn-carbonate precipitation may have occluded porosity in the surficial sediments, thus establishing an effective barrier to SO2-4 exchange with overlying seawater. Similar isotopic and mineralogic characteristics from both the Molango and TaoJiang deposits, widely separated in geologic time and

Extending the Capabilities of Closed-loop Distributed Engine Control Simulations Using LAN Communication

NASA Technical Reports Server (NTRS)

Aretskin-Hariton, Eliot D.; Zinnecker, Alicia Mae; Culley, Dennis E.

2014-01-01

Distributed Engine Control (DEC) is an enabling technology that has the potential to advance the state-of-the-art in gas turbine engine control. To analyze the capabilities that DEC offers, a Hardware-In-the-Loop (HIL) test bed is being developed at NASA Glenn Research Center. This test bed will support a systems-level analysis of control capabilities in closed-loop engine simulations. The structure of the HIL emulates a virtual test cell by implementing the operator functions, control system, and engine on three separate computers. This implementation increases the flexibility and extensibility of the HIL. Here, a method is discussed for implementing these interfaces by connecting the three platforms over a dedicated Local Area Network (LAN). This approach is verified using the Commercial Modular Aero-Propulsion System Simulation 40k (C-MAPSS40k), which is typically implemented on one computer. There are marginal differences between the results from simulation of the typical and the three-computer implementation. Additional analysis of the LAN network, including characterization of network load, packet drop, and latency, is presented. The three-computer setup supports the incorporation of complex control models and proprietary engine models into the HIL framework.

The relationship between a deformation-based eddy parameterization and the LANS-α turbulence model

NASA Astrophysics Data System (ADS)

Bachman, Scott D.; Anstey, James A.; Zanna, Laure

2018-06-01

A recent class of ocean eddy parameterizations proposed by Porta Mana and Zanna (2014) and Anstey and Zanna (2017) modeled the large-scale flow as a non-Newtonian fluid whose subgridscale eddy stress is a nonlinear function of the deformation. This idea, while largely new to ocean modeling, has a history in turbulence modeling dating at least back to Rivlin (1957). The new class of parameterizations results in equations that resemble the Lagrangian-averaged Navier-Stokes-α model (LANS-α, e.g., Holm et al., 1998a). In this note we employ basic tensor mathematics to highlight the similarities between these turbulence models using component-free notation. We extend the Anstey and Zanna (2017) parameterization, which was originally presented in 2D, to 3D, and derive variants of this closure that arise when the full non-Newtonian stress tensor is used. Despite the mathematical similarities between the non-Newtonian and LANS-α models which might provide insight into numerical implementation, the input and dissipation of kinetic energy between these two turbulent models differ.

Sniffer Channel Selection for Monitoring Wireless LANs

NASA Astrophysics Data System (ADS)

Song, Yuan; Chen, Xian; Kim, Yoo-Ah; Wang, Bing; Chen, Guanling

Wireless sniffers are often used to monitor APs in wireless LANs (WLANs) for network management, fault detection, traffic characterization, and optimizing deployment. It is cost effective to deploy single-radio sniffers that can monitor multiple nearby APs. However, since nearby APs often operate on orthogonal channels, a sniffer needs to switch among multiple channels to monitor its nearby APs. In this paper, we formulate and solve two optimization problems on sniffer channel selection. Both problems require that each AP be monitored by at least one sniffer. In addition, one optimization problem requires minimizing the maximum number of channels that a sniffer listens to, and the other requires minimizing the total number of channels that the sniffers listen to. We propose a novel LP-relaxation based algorithm, and two simple greedy heuristics for the above two optimization problems. Through simulation, we demonstrate that all the algorithms are effective in achieving their optimization goals, and the LP-based algorithm outperforms the greedy heuristics.

Prediction of dissolved oxygen concentration in hypoxic river systems using support vector machine: a case study of Wen-Rui Tang River, China.

PubMed

Ji, Xiaoliang; Shang, Xu; Dahlgren, Randy A; Zhang, Minghua

2017-07-01

Accurate quantification of dissolved oxygen (DO) is critically important for managing water resources and controlling pollution. Artificial intelligence (AI) models have been successfully applied for modeling DO content in aquatic ecosystems with limited data. However, the efficacy of these AI models in predicting DO levels in the hypoxic river systems having multiple pollution sources and complicated pollutants behaviors is unclear. Given this dilemma, we developed a promising AI model, known as support vector machine (SVM), to predict the DO concentration in a hypoxic river in southeastern China. Four different calibration models, specifically, multiple linear regression, back propagation neural network, general regression neural network, and SVM, were established, and their prediction accuracy was systemically investigated and compared. A total of 11 hydro-chemical variables were used as model inputs. These variables were measured bimonthly at eight sampling sites along the rural-suburban-urban portion of Wen-Rui Tang River from 2004 to 2008. The performances of the established models were assessed through the mean square error (MSE), determination coefficient (R 2 ), and Nash-Sutcliffe (NS) model efficiency. The results indicated that the SVM model was superior to other models in predicting DO concentration in Wen-Rui Tang River. For SVM, the MSE, R 2 , and NS values for the testing subset were 0.9416 mg/L, 0.8646, and 0.8763, respectively. Sensitivity analysis showed that ammonium-nitrogen was the most significant input variable of the proposal SVM model. Overall, these results demonstrated that the proposed SVM model can efficiently predict water quality, especially for highly impaired and hypoxic river systems.

[The innovation of warm disease theory in the Ming Dynasty before Wen yi lun On Pestilence].

PubMed

Zhang, Zhi-bin

2008-10-01

Some doctors of the Ming dynasty raised subversive doubts against the traditional viewpoints of "exogenous cold disease is warm-heat" before the emergence of Wen yi lun (On Pestilence), holding that warm-heat disease "is contracted in different seasons instead of being transformed from cold to warm and/or heat". The conception of the separation of warm-heat disease and exogenous cold disease had changed from obscure to clear. As the idea became clear, the recognition on the new affection of warm, heat, summer-heat, pestilent pathogen was formed, and the idea that the pathogens of summer-heat and warm entered the human body through the mouth and nostrils was put forward. The six-channel syndrome differentiation of warm disease and the five sweat-resolving methods in pestilence raised by the doctors of this period are the aspects of the differential diagnosis of syndrome and treatment in warm diseases, and deserve to be paid attention to.

The variation of riverbed material due to tropical storms in Shi-Wen River, Taiwan.

PubMed

Lin, Chin-Ping; Wang, Yu-Min; Tfwala, Samkele S; Chen, Ching-Nuo

2014-01-01

Taiwan, because of its location, is a flood prone region and is characterised by typhoons which brings about two-thirds to three quarters of the annual rainfall amount. Consequently, enormous flows result in rivers and entrain some fractions of the grains that constitute the riverbed. Hence, the purpose of the study is to quantify the impacts of these enormous flows on the distribution of grain size in riverbeds. The characteristics of riverbed material prior to and after the typhoon season are compared in Shi-Wen River located at southern Taiwan. These include grain size variation, bimodality, and roughness coefficient. A decrease (65%) and increase (50%) in geometric mean size of grains were observed for subsurface and surface bed material, respectively. Geometric standard deviation decreased in all sites after typhoon. Subsurface material was bimodal prior to typhoons and polymodal after. For surface material, modal class is in the gravel class, while after typhoons it shifts towards cobble class. The reduction in geometric mean resulted to a decrease in roughness coefficient by up to 30%. Finally, the relationship of Shields and Froude numbers are studied and a change in the bed form to antidunes and transition form is observed, respectively.

The severity of hereditary porphyria is modulated by the porphyrin exporter and Lan antigen ABCB6

PubMed Central

Fukuda, Yu; Cheong, Pak Leng; Lynch, John; Brighton, Cheryl; Frase, Sharon; Kargas, Vasileios; Rampersaud, Evadnie; Wang, Yao; Sankaran, Vijay G.; Yu, Bing; Ney, Paul A.; Weiss, Mitchell J.; Vogel, Peter; Bond, Peter J.; Ford, Robert C.; Trent, Ronald J.; Schuetz, John D.

2016-01-01

Hereditary porphyrias are caused by mutations in genes that encode haem biosynthetic enzymes with resultant buildup of cytotoxic metabolic porphyrin intermediates. A long-standing open question is why the same causal porphyria mutations exhibit widely variable penetrance and expressivity in different individuals. Here we show that severely affected porphyria patients harbour variant alleles in the ABCB6 gene, also known as Lan, which encodes an ATP-binding cassette (ABC) transporter. Plasma membrane ABCB6 exports a variety of disease-related porphyrins. Functional studies show that most of these ABCB6 variants are expressed poorly and/or have impaired function. Accordingly, homozygous disruption of the Abcb6 gene in mice exacerbates porphyria phenotypes in the Fechm1Pas mouse model, as evidenced by increased porphyrin accumulation, and marked liver injury. Collectively, these studies support ABCB6 role as a genetic modifier of porphyria and suggest that porphyrin-inducing drugs may produce excessive toxicities in individuals with the rare Lan(−) blood type. PMID:27507172

Tablet PC as a mobil PACS terminal using wireless LAN

NASA Astrophysics Data System (ADS)

Tsao, Bo-Shen; Ching, Yu-Tai; Lee, Wen-Jeng; Chen, Shyh-Jye; Chang, Chia-Hung; Chen, Chien-Jung; Yen, York; Lee, Yuan-Ten

2003-05-01

A PACS mobile terminal has applications in ward round, emergency room and remote teleradiology consultation. Personal Digital Assistants (PDAs) have the highest mobility and are used for many medical applications. However, their roles are limited in the field of radiology due to small screen size. In this study, we built a wireless PACS terminal using a hand-held tablet-PC. A tablet PC (X-pilot, LEO systems, Taiwan) running the WinCE operating systems was used as our mobile PACS terminal. This device is equipped with 800×600 resolution 10.4 inch TFT monitor. The network connection between the tablet PC and the server was linked via wireless LAN (IEEE 802.11b).

Access Protocol For An Industrial Optical Fibre LAN

NASA Astrophysics Data System (ADS)

Senior, John M.; Walker, William M.; Ryley, Alan

1987-09-01

A structure for OSI levels 1 and 2 of a local area network suitable for use in a variety of industrial environments is reported. It is intended that the LAN will utilise optical fibre technology at the physical level and a hybrid of dynamically optimisable token passing and CSMA/CD techniques at the data link (IEEE 802 medium access control - logical link control) level. An intelligent token passing algorithm is employed which dynamically allocates tokens according to the known upper limits on the requirements of each device. In addition a system of stochastic tokens is used to increase efficiency when the stochastic traffic is significant. The protocol also allows user-defined priority systems to be employed and is suitable for distributed or centralised implementation. The results of computer simulated performance characteristics for the protocol using a star-ring topology are reported which demonstrate its ability to perform efficiently with the device and traffic loads anticipated within an industrial environment.

The Variation of Riverbed Material due to Tropical Storms in Shi-Wen River, Taiwan

PubMed Central

Lin, Chin-Ping; Tfwala, Samkele S.; Chen, Ching-Nuo

2014-01-01

Taiwan, because of its location, is a flood prone region and is characterised by typhoons which brings about two-thirds to three quarters of the annual rainfall amount. Consequently, enormous flows result in rivers and entrain some fractions of the grains that constitute the riverbed. Hence, the purpose of the study is to quantify the impacts of these enormous flows on the distribution of grain size in riverbeds. The characteristics of riverbed material prior to and after the typhoon season are compared in Shi-Wen River located at southern Taiwan. These include grain size variation, bimodality, and roughness coefficient. A decrease (65%) and increase (50%) in geometric mean size of grains were observed for subsurface and surface bed material, respectively. Geometric standard deviation decreased in all sites after typhoon. Subsurface material was bimodal prior to typhoons and polymodal after. For surface material, modal class is in the gravel class, while after typhoons it shifts towards cobble class. The reduction in geometric mean resulted to a decrease in roughness coefficient by up to 30%. Finally, the relationship of Shields and Froude numbers are studied and a change in the bed form to antidunes and transition form is observed, respectively. PMID:24526910

Will available bit rate (ABR) services give us the capability to offer virtual LANs over wide-area ATM networks?

NASA Astrophysics Data System (ADS)

Ferrandiz, Ana; Scallan, Gavin

1995-10-01

The available bit rate (ABR) service allows connections to exceed their negotiated data rates during the life of the connections when excess capacity is available in the network. These connections are subject to flow control from the network in the event of network congestion. The ability to dynamically adjust the data rate of the connection can provide improved utilization of the network and be a valuable service to end users. ABR type service is therefore appropriate for the transmission of bursty LAN traffic over a wide area network in a manner that is more efficient and cost effective than allocating bandwdith at the peak cell rate. This paper describes the ABR service and discusses if it is realistic to operate a LAN like service over a wide area using ABR.

Laser Atmospheric Transmitter Receiver-Network (LAnTeRN): A new approach for active measurement of atmospheric greenhouse gases

NASA Astrophysics Data System (ADS)

Dobler, J. T.; Braun, M.; Zaccheo, T.

2012-12-01

The Laser Atmospheric Transmitter Receiver-Network (LAnTeRN) is a new measurement concept that will enable local, regional and continental determination of key greenhouse gases, with unparalleled accuracy and precision. This new approach will offer the ability to make low bias, high precision, quasi-continuous, measurements to the accuracies required for separating anthropogenic and biogenic sources and sinks. In 2004 ITT Exelis developed an airborne demonstration unit, based on an intensity modulated continuous wave (IM-CW) lidar approach, for actively measuring atmospheric CO2 and O2. The multi-functional fiber laser lidar (MFLL) system relies on low peak power, high reliability, and efficient telecom laser components to implement this unique measurement approach. While evaluating methods for discriminating against thin clouds for the MFLL instrument, a new measurement concept was conceived. LAnTeRN has several fundamental characteristics in common with the MFLL instrument, but is a fundamentally different implementation and capability. The key difference is that LAnTeRN operates in transmission rather than in the traditional backscatter lidar configuration, which has several distinct advantages. Operating as a forward scatter, bistatic lidar system, LAnTeRN enables consideration of continuous monitoring from a geostationary orbit to multiple locations on the ground. Having the receivers on the ground significantly lowers cost and risk compared to an all space based mission, and allows the transmitter subsystem to be implemented, near term, as a hosted payload. Furthermore, the LAnTeRN measurement approach is also applicable for ground to ground measurements where high precision measurements over a long open path is required, such as facilities monitoring, or monitoring of passive volcanoes and fault lines. Using narrow linewidth laser sources allows flexibility to select the position on the absorption feature being probed. This feature allows for weighting the

A multicenter, observational study of lanreotide depot/autogel (LAN) in patients with acromegaly in the United States: 2-year experience from the SODA registry.

PubMed

Salvatori, Roberto; Gordon, Murray B; Woodmansee, Whitney W; Ioachimescu, Adriana G; Carver, Don W; Mirakhur, Beloo; Cox, David; Molitch, Mark E

2017-12-01

This analysis evaluates the 2-year effectiveness and safety of lanreotide depot/autogel (LAN), as well as treatment convenience and acromegaly symptom relief, from the Somatuline ® Depot for Acromegaly (SODA) registry, a post-marketing, open-label, observational, multicenter, United States registry study. Patients with acromegaly treated with LAN were eligible for enrollment. Demographics, LAN dose, extended dosing interval (EDI) (interval of injections ≥42 days), insulin-like growth factor 1 (IGF-1), growth hormone (GH), glycated hemoglobin, adverse events (AEs), injection convenience, and symptom data were collected. As of September 29, 2014, 241 patients were enrolled in SODA. IGF-1 levels below age- and gender-adjusted upper normal limit (ULN) were achieved in 71.2% at month (M) 12 and 74.4% at M24; GH ≤2.5 µg/L in 83.3% at M12 and 80.0% at M24; GH <1.0 µg/L in 61.7% at M12 and 61.4% at M24. Both IGF-1 < ULN and GH ≤2.5 µg/L were achieved in 65.0% at M12 and 54.8% at M24; both IGF-1 < ULN and GH < 1.0 µg/L were achieved in 51.7 and 42.9% at M12 and M24, respectively. EDI regimen was 5.0% at baseline and 12.0% at M24. At M24, acromegaly symptoms appeared stable or improved. The most common AE was arthralgia (25.7%). Among 106 serious AEs reported by 42 patients, 10 were deemed related to therapy in 9 patients. At M24, 73.1% of patients rated LAN as convenient. SODA indicates 2-year biochemical control with majority of patients achieving both IGF-1 < ULN and GH ≤2.5 µg/L. LAN was generally well tolerated with no new or unexpected safety signals reported during the observation period. clinicaltrials.gov Clinical Trial Identifier: NCT00686348.

Phytoplankton Imaging and Analysis System: Instrumentation for Field and Laboratory Acquisition, Analysis and WWW/LAN-Based Sharing of Marine Phytoplankton Data (DURIP)

DTIC Science & Technology

2000-09-30

networks (LAN), (3) quantifying size, shape, and other parameters of plankton cells and colonies via image analysis and image reconstruction, and (4) creating educational materials (e.g. lectures, videos etc.).

Would the "Real" Girl Gamer Please Stand Up? Gender, LAN Cafes and the Reformulation of the "Girl" Gamer

ERIC Educational Resources Information Center

Beavis, Catherine; Charles, Claire

2007-01-01

In this paper we consider the significance of cyber "LAN" cafes as sites where on and off-line practices meet in way that complicates binary notions of the gendered gamer. Existing research into computer games culture suggests a male dominated environment and points to girls' lower levels of competence and participation in games. Building on…

156 Mbps Ultrahigh-Speed Wireless LAN Prototype in the 38 GHz Band

NASA Astrophysics Data System (ADS)

Wu, Gang; Inoue, Masugi; Murakami, Homare; Hase, Yoshihiro

2001-12-01

This paper describes a 156 Mbps ultrahigh-speed wireless LAN operating in the 38 GHz millimeter (mm)-wave band. The system is a third prototype developed at the Communications Research Laboratory since 1998. Compared with the previous prototypes, the system is faster (156 Mbps) and smaller (volume of radio transceiver less than 1000 cc), it has a larger service area (two overlapping basic service sets), and a longer transmission distance (the protocol can support a distance of more than two hundred meters). The development is focused on the physical layer and the data link control layer, and thus a GMSK-based mm-wave transceiver and an enhanced RS-ISMA (reservation-based slotted idle signal multiple access) protocol are key development components. This paper describes the prototype system's design, configuration, and implementation.

Nuclear stopping and collective flow in CSR/LanZhou energy region

NASA Astrophysics Data System (ADS)

Luo, X.-F.; Dong, X.; Shao, M.; Li, C.; Chen, H.-F.; Wu, K.-J.; Xu, H.-S.

2011-06-01

Nuclear stopping and collective flow for two pairs of symmetric colliding nuclei: 238U+238U and 129Xe+129Xe, which are proposed to be accelerated on Cooling Storage Ring (CSR), External Target Facility (ETF), LanZhou, China, are studied by a hadronic transport model ART1.0. The incident beam energy of Uranium and Xenon can be delivered up to 520 MeV/nucleon and 900MeV/nucleon, respectively. At this CSR energy region, the hot, dense nuclear matter are thought to be obtained in the lab, which is an idea circumstance to study the nuclear equation of state (EoS). As deformation of the Uranium nuclei, it is predicted that significant large baryon density in the tip-tip U+U collision patterns and the large elliptic flow in body-body collision pattern are both avail to study the nuclear EoS.

Compact and high-sensitivity 100-Gb/s (4 × 25 Gb/s) APD-ROSA with a LAN-WDM PLC demultiplexer.

PubMed

Yoshimatsu, Toshihide; Nada, Masahiro; Oguma, Manabu; Yokoyama, Haruki; Ohno, Tetsuichiro; Doi, Yoshiyuki; Ogawa, Ikuo; Takahashi, Hiroshi; Yoshida, Eiji

2012-12-10

We demonstrate an integrated 100 GbE receiver optical sub-assembly (ROSA) that incorporates a monolithic four-channel avalanche photodiode (APD) array and a planer lightwave circuit (PLC) based LAN-WDM demultiplexer. A record minimum receiver sensitivity of -20 dBm and 50-km error-free SMF transmission without an optical amplifier have been achieved.

MaGelLAn 1.0: a software to facilitate quantitative and population genetic analysis of maternal inheritance by combination of molecular and pedigree information.

PubMed

Ristov, Strahil; Brajkovic, Vladimir; Cubric-Curik, Vlatka; Michieli, Ivan; Curik, Ino

2016-09-10

Identification of genes or even nucleotides that are responsible for quantitative and adaptive trait variation is a difficult task due to the complex interdependence between a large number of genetic and environmental factors. The polymorphism of the mitogenome is one of the factors that can contribute to quantitative trait variation. However, the effects of the mitogenome have not been comprehensively studied, since large numbers of mitogenome sequences and recorded phenotypes are required to reach the adequate power of analysis. Current research in our group focuses on acquiring the necessary mitochondria sequence information and analysing its influence on the phenotype of a quantitative trait. To facilitate these tasks we have produced software for processing pedigrees that is optimised for maternal lineage analysis. We present MaGelLAn 1.0 (maternal genealogy lineage analyser), a suite of four Python scripts (modules) that is designed to facilitate the analysis of the impact of mitogenome polymorphism on quantitative trait variation by combining molecular and pedigree information. MaGelLAn 1.0 is primarily used to: (1) optimise the sampling strategy for molecular analyses; (2) identify and correct pedigree inconsistencies; and (3) identify maternal lineages and assign the corresponding mitogenome sequences to all individuals in the pedigree, this information being used as input to any of the standard software for quantitative genetic (association) analysis. In addition, MaGelLAn 1.0 allows computing the mitogenome (maternal) effective population sizes and probability of mitogenome (maternal) identity that are useful for conservation management of small populations. MaGelLAn is the first tool for pedigree analysis that focuses on quantitative genetic analyses of mitogenome data. It is conceived with the purpose to significantly reduce the effort in handling and preparing large pedigrees for processing the information linked to maternal lines. The software source

Protocol and Topology Issues for Wide-Area Satellite Interconnection of Terrestrial Optical LANs

NASA Astrophysics Data System (ADS)

Parraga, N.

2002-01-01

Apart from broadcasting, the satellite business is targeting niche markets. Wide area interconnection is considered as one of these niche markets, since it addresses operators and business LANs (B2B, business to business) in remote areas where terrestrial infrastructure is not available. These LANs - if high-speed - are typically based on optical networks such as SONET. One of the advantages of SONET is its architecture flexibility and capacity to transport all kind of applications including multimedia with a range of different transmission rates. The applications can be carried by different protocols among which the Internet Protocol (IP) or the Asynchronous Transfer Mode (ATM) are the most prominent ones. Thus, the question arises how these protocols can be interconnected via the satellite segment. The paper addresses several solutions for interworking with different protocols. For this investigation we distinguish first of all between the topology and the switching technology of the satellites. In case of a star network with transparent satellite, the satellite protocol consists of physical layer and data layer which can be directly interconnected with layer 2 interworking function to their terrestrial counterparts in the SONET backbone. For regenerative satellites the situation is more complex: here we need to distinguish the types of transport protocols being used in the terrestrial and satellite segment. Whereas IP, ATM, MPEG dominate in the terrestrial networks, satellite systems usually do not follow these standards. Some might employ minor additions (for instance, satellite specific packet headers), some might be completely proprietary. In general, interworking must be done for the data plane on top of layer 2 (data link layer), whereas for the signaling plane the interworking is on top of layer 3. In the paper we will discuss the protocol stacks for ATM, IP, and MPEG with a regenerative satellite system. As an example we will use the EuroSkyWay satellite

Source mechanism of the 2006 M5.1 Wen'an Earthquake determined from a joint inversion of local and teleseismic broadband waveform data

NASA Astrophysics Data System (ADS)

Huang, J.; Ni, S.; Niu, F.; Fu, R.

2007-12-01

On July 4th, 2006, a magnitude 5.1 earthquake occurred at Wen'an, {~}100 km south of Beijing, which was felt at Beijing metropolitan area. To better understand the regional tectonics, we have inverted local and teleseismic broadband waveform data to determine the focal mechanism of this earthquake. We selected waveform data of 9 stations from the recently installed Beijing metropolitan digital Seismic Network (BSN). These stations are located within 600 km and cover a good azimuthal range to the earthquake. To better fit the lower amplitude P waveform, we employed two different weights for the P wave and surface wave arrivals, respectively. A grid search method was employed to find the strike, dip and slip of the earthquake that best fits the P and surface waveforms recorded at all the three components (the tangential component of the P-wave arrivals was not used). Synthetic waveforms were computed with an F-K method. Two crustal velocity models were used in the synthetic calculation to reflect a rapid east-west transition in crustal structure observed by seismic and geological studies in the study area. The 3D grid search results in reasonable constraints on the fault geometry and the slip vector with a less well determined focal depth. As such we combined teleseismic waveform data from 8 stations of the Global Seismic Network in a joint inversion. Clearly identifiable depth phases (pP, sP) recorded in the teleseismic stations obviously provided a better constraint on the resulting source depth. Results from the joint inversion indicate that the Wen'an earthquake is mainly a right-lateral strike slip event (-150°) which occurred at a near vertical (dip, 80° ) NNE trend (210°º) fault. The estimated focal depth is {~}14- 15km, and the moment magnitude is 5.1. The estimated fault geometry here agrees well with aftershock distribution and is consistent with the major fault systems in the area which were developed under a NNE-SSW oriented compressional stress field

Wen-Luo-Tong Prevents Glial Activation and Nociceptive Sensitization in a Rat Model of Oxaliplatin-Induced Neuropathic Pain.

PubMed

Deng, Bo; Jia, Liqun; Pan, Lin; Song, Aiping; Wang, Yuanyuan; Tan, Huangying; Xiang, Qing; Yu, Lili; Ke, Dandan

2016-01-01

One of the main dose-limiting complications of the chemotherapeutic agent oxaliplatin (OXL) is painful neuropathy. Glial activation and nociceptive sensitization may be responsible for the mechanism of neuropathic pain. The Traditional Chinese Medicine (TCM) Wen-luo-tong (WLT) has been widely used in China to treat chemotherapy induced neuropathic pain. However, there is no study on the effects of WLT on spinal glial activation induced by OXL. In this study, a rat model of OXL-induced chronic neuropathic pain was established and WLT was administrated. Pain behavioral tests and morphometric examination of dorsal root ganglia (DRG) were conducted. Glial fibrillary acidic protein (GFAP) immunostaining was performed, glial activation was evaluated, and the excitatory neurotransmitter substance P (SP) and glial-derived proinflammatory cytokine tumor necrosis factor-α (TNF-α) were analyzed. WLT treatment alleviated OXL-induced mechanical allodynia and mechanical hyperalgesia. Changes in the somatic, nuclear, and nucleolar areas of neurons in DRG were prevented. In the spinal dorsal horn, hypertrophy and activation of GFAP-positive astrocytes were averted, and the level of GFAP mRNA decreased significantly. Additionally, TNF-α mRNA and protein levels decreased. Collectively, these results indicate that WLT reversed both glial activation in the spinal dorsal horn and nociceptive sensitization during OXL-induced chronic neuropathic pain in rats.

Chest injuries associated with earthquakes: an analysis of injuries sustained during the 2008 Wen-Chuan earthquake in China.

PubMed

Hu, Jia; Guo, Ying-Qiang; Zhang, Er-Yong; Tan, Jin; Shi, Ying-Kang

2010-08-01

The goal of this study was to analyze the patterns, therapeutic modalities, and short-term outcomes of patients with chest injuries in the aftermath of the Wen-Chuan earthquake, which occurred on May 12, 2008 and registered 8.0 on the Richter scale. Of the 1522 patients who were referred to the West China Hospital of Sichuan University from May 12 to May 27, 169 patients (11.1%) had suffered major chest injuries. The type of injury, the presence of infection, Abbreviated Injury Score (AIS 2005), New Injury Severity Score (NISS), treatment, and short-term outcome were all documented for each case. Isolated chest injuries were diagnosed in 129 patients (76.3%), while multiple injuries with a major chest trauma were diagnosed in 40 patients (23.7%). The mean AIS and the median NISS of the hospitalized patients with chest injuries were 2.5 and 13, respectively. The mortality rate was 3.0% (5 patients). Most of the chest injuries were classified as minor to moderate trauma; however, coexistent multiple injuries and subsequent infection should be carefully considered in medical response strategies. Coordinated efforts among emergency medical support groups and prior training in earthquake preparedness and rescue in earthquake-prone areas are therefore necessary for efficient evacuation and treatment of catastrophic casualties.

Occurrence and photodegradation of methylmercury in surface water of Wen-Rui-Tang River network, Wenzhou, China.

PubMed

Pan, Shuihong; Feng, Chuchu; Lin, Jialu; Cheng, Lidong; Wang, Chengjun; Zuo, Yuegang

2017-04-01

The spatial distribution and seasonal variations of methylmercury (MeHg) in Wen-Rui-Tang (WRT) River network were investigated by monitoring the MeHg concentrations in surface water samples collected from 30 sites across the river network over four seasons. Detection frequencies and concentrations of MeHg were generally higher in January, indicating that low sunlight irradiation, wind speed, and temperature conditions might enhance the persistence of MeHg in surface water. The MeHg levels varied with sampling locations, with the highest concentrations being observed in the industrial area especially around wastewater outfall, revealing that the mercury contamination in WRT River mainly comes from the industrial wastewater. Photodegradation of MeHg in WRT River surface water and the effects of natural constituents such as fulvic acid (FA), ferric ions (Fe 3+ ), nitrate (NO 3 - ), and dissolved oxygen on the MeHg photodegradation in aqueous solutions were studied under the simulated sunlight. The experimental data indicated that the indirect photodecomposition of MeHg occurred in WRT River surface water. Photodegradation of MeHg in FA solution was initiated by triplet 3 FA* or MeHg-FA* via electron transfer interaction under light irradiations. The Fe 3+ and NO 3 - can absorb light energy to produce ·OH and enhance the photochemical degradation of MeHg. The MeHg photodecompositions in FA, nitrate, and Fe 3+ solutions were markedly accelerated after removing the dissolved oxygen.

NHEXAS PHASE I ARIZONA STUDY--STANDARD OPERATING PROCEDURE FOR OPERATION AND MAINTENANCE OF THE LAN AND RELATED MICROCOMPUTER ENVIRONMENT (UA-D-1.1)

EPA Science Inventory

The purpose of this SOP is to describe procedures for using and maintaining the local area network (LAN) and related microcomputer equipment at the HRP Site of the Arizona Prevention Center. These methods were used for all data operations and maintenance routines during the Ariz...

Measurements of light at night (LAN) for a sample of female school teachers

PubMed Central

Rea, Mark S.; Brons, Jennifer A.; Figueiro, Mariana G.

2012-01-01

Epidemiological studies have shown an association between rotating shiftwork and breast cancer (BC) risk. Recently, light at night (LAN) measured by satellite photometry and by self-reports of bedroom brightness has been shown to be associated with BC risk, irrespective of shiftwork history. Importance has been placed on these associations because retinal light exposures at night can suppress the hormone melatonin and/or disrupt circadian entrainment to the local 24-h light-dark cycle. The present study examined whether it was valid to use satellite photometry and self-reports of brightness to characterize light, as it might stimulate the circadian system and thereby affect BC incidence. Calibrated photometric measurements were made at the bedroom windows and in the bedrooms of a sample of female school teachers, who worked regular dayshifts and lived in a variety of satellite-measured sky brightness categories. The light levels at both locations were usually very low and were independent of the amount of satellite-measured light. Calibrated photometric measurements were also obtained at the corneas of these female school teachers together with calibrated accelerometer measurements for seven consecutive days and evenings. Based upon these personal light exposure and activity measurements, the female teachers who participated in this study did not have disrupted light-dark cycles like those associated with rotating shiftworkers who do exhibit a higher risk for BC. Rather, this sample of female school teachers had 24-h light-dark and activity-rest patterns very much like those experienced by dayshift nurses examined in an earlier study who are not at an elevated risk of BC. No relationship was found between the amount of satellite-measured light levels and the 24-h light-dark patterns these women experienced. It was concluded from the present study that satellite photometry is unrelated to personal light exposures as they might affect melatonin suppression and

Assessments on landslide susceptibility in the Tseng-wen reservoir watershed, Taiwan

NASA Astrophysics Data System (ADS)

Chen, Yu-Chin; Chen, Yung-Chau; Chen, Wen-Fu

2014-05-01

Typhoon Morakot under the strong influence of southwestern monsoon wind struck Taiwan on 8 August 2009, and dumped record-breaking rains in southern Taiwan. It triggered enormous landslides in mountains and severe flooding in low-lying areas. In addition, it destroyed or damaged houses, agricultural fields, roads, bridges, and other infrastructure facilities, causing massive economic loss and, more tragically, human casualties. In order to evaluate landslide hazard and risk assessment, it is important to understand the potential sites of landslide and their spatial distribution. Multi-temporal satellite images and geo-spatial data are used to build landslide susceptibility map for the post-disaster in the Tseng-wen reservoir watershed in this research. Elevation, slope, aspect, NDVI (normalized differential vegetation index), relief, roughness, distance to river, and distance to road are the considered factors for estimating landslide susceptibility. Maximum hourly rainfall and total rainfall, accompanied with typhoon event, are selected as the trigger factors of landslide events. Logistic regression analysis is adopted as the statistical method to model landslide susceptibility. The assessed susceptibility is represented in 4 levels which are high, high-intermediate, intermediate, and low level, respectively. Landslide spatial distribution can be depicted as a landslide susceptibility map with respect to each considered influence factors for a specified susceptible level. The landslide areas are about 358 ha and 1,485 ha before and after typhoon Morakot. The new landslide area, induced by typhoon Morakot, is as almost 4 times as the landslide area before typhoon Morakot. In addition, there is about 44.56% landslide area elevation ranging from 500m to 1000m and about 57.22% average slope ranging from 30° to 45° of landslide area. Furthermore, the devastating landslides were happened at those sites close to rivers, exposed area, and area with big land cover change

A Seamless Handoff Scheme with Access Point Load Balance for Real-Time Services Support in 802.11 Wireless LANs

NASA Astrophysics Data System (ADS)

Manodham, Thavisak; Loyola, Luis; Miki, Tetsuya

IEEE 802.11 wirelesses LANs (WLANs) have been rapidly deployed in enterprises, public areas, and households. Voice-over-IP (VoIP) and similar applications are now commonly used in mobile devices over wireless networks. Recent works have improved the quality of service (QoS) offering higher data rates to support various kinds of real-time applications. However, besides the need for higher data rates, seamless handoff and load balancing among APs are key issues that must be addressed in order to continue supporting real-time services across wireless LANs and providing fair services to all users. In this paper, we introduce a novel access point (AP) with two transceivers that improves network efficiency by supporting seamless handoff and traffic load balancing in a wireless network. In our proposed scheme, the novel AP uses the second transceiver to scan and find neighboring STAs in the transmission range and then sends the results to neighboring APs, which compare and analyze whether or not the STA should perform a handoff. The initial results from our simulations show that the novel AP module is more effective than the conventional scheme and a related work in terms of providing a handoff process with low latency and sharing traffic load with neighbor APs.

Land cover of oases and forest in XinJiang, China retrieved from ASTER data

NASA Astrophysics Data System (ADS)

Buhe, Aosier; Tsuchiya, K.; Kaneko, M.; Ohtaishi, N.; Halik, Mahmut

ASTER aboard NASA’s satellite Terra is a high-resolution multispectral radiometer of 14 bands. The spatial resolution is 15 m in VNIR, 30 m in SWIR and 90 m in TIR spectra, respectively. With the data observed with ASTER, the land cover classification is produced for the Tarim Diversifolious Poplar Protection Area along the Tarim River in the northern Tarim Basin (Taklamakan Desert) in XinJiang, China. The classification of the vegetation (plants) in the arid and semiarid regions using remote-sensing technology is very difficult. Because the cause has low vegetable cover density and the influence of reflection from background soil is large. ASTER data are effective in studying the spectrum characteristics of land cover in arid and semiarid regions. The sensor has several bands in the shortwave infrared wavelength region that is designed for exploration of earth resources and study of the arid and semiarid region natural environment. However, we are not clear combination of which band is the most effective in research of the arid region like the Taklamakan desert in the data of 14 bands of ASTER. The optimum index factor (OIF), based on total variance within bands and correlation coefficient between bands, is a statistical approach to rank all possible three-band combinations. In the process of analyzing the data, the pixel sizes of all the data are converted (layer stacking and re-sampling) into consistent same size of 15 m. The three-band composite with the largest OIF value will have most information (as measured by variance) with the least amount of duplication (as measured by correlation). We used the OIF technique to rank all three-band combinations of ASTER original 14-band data over Tarim River Poplar Protection Area. Our study indicates that RGB color overlay using atmospheric corrected ASTER original bands 2, 3 (VNIR), and 6 (SWIR) has the highest OIF. When NDVI is considered as one ASTER band, highest OIF will have by carrying out bands 3 (VNIR), 4

Cluster-Based Multipolling Sequencing Algorithm for Collecting RFID Data in Wireless LANs

NASA Astrophysics Data System (ADS)

Choi, Woo-Yong; Chatterjee, Mainak

2015-03-01

With the growing use of RFID (Radio Frequency Identification), it is becoming important to devise ways to read RFID tags in real time. Access points (APs) of IEEE 802.11-based wireless Local Area Networks (LANs) are being integrated with RFID networks that can efficiently collect real-time RFID data. Several schemes, such as multipolling methods based on the dynamic search algorithm and random sequencing, have been proposed. However, as the number of RFID readers associated with an AP increases, it becomes difficult for the dynamic search algorithm to derive the multipolling sequence in real time. Though multipolling methods can eliminate the polling overhead, we still need to enhance the performance of the multipolling methods based on random sequencing. To that extent, we propose a real-time cluster-based multipolling sequencing algorithm that drastically eliminates more than 90% of the polling overhead, particularly so when the dynamic search algorithm fails to derive the multipolling sequence in real time.

U.S.-MEXICO BORDER PROGRAM ARIZONA BORDER STUDY--STANDARD OPERATING PROCEDURE FOR OPERATION AND MAINTENANCE OF THE LAN AND RELATED MICROCOMPUTER ENVIRONMENT (UA-D-1.1)

EPA Science Inventory

The purpose of this SOP is to describe procedures for using and maintaining the local area network (LAN) and related microcomputer equipment at the Health Related Professions site at the University of Arizona. These methods were used for all data operations and maintenance routi...

Towards secure quantum key distribution protocol for wireless LANs: a hybrid approach

NASA Astrophysics Data System (ADS)

Naik, R. Lalu; Reddy, P. Chenna

2015-12-01

The primary goals of security such as authentication, confidentiality, integrity and non-repudiation in communication networks can be achieved with secure key distribution. Quantum mechanisms are highly secure means of distributing secret keys as they are unconditionally secure. Quantum key distribution protocols can effectively prevent various attacks in the quantum channel, while classical cryptography is efficient in authentication and verification of secret keys. By combining both quantum cryptography and classical cryptography, security of communications over networks can be leveraged. Hwang, Lee and Li exploited the merits of both cryptographic paradigms for provably secure communications to prevent replay, man-in-the-middle, and passive attacks. In this paper, we propose a new scheme with the combination of quantum cryptography and classical cryptography for 802.11i wireless LANs. Since quantum cryptography is premature in wireless networks, our work is a significant step forward toward securing communications in wireless networks. Our scheme is known as hybrid quantum key distribution protocol. Our analytical results revealed that the proposed scheme is provably secure for wireless networks.

Establishment of the low-level radwaste classification using the dose-to-curie technique at the Lan-Yu Temporary Storage Site, Taiwan

DOE Office of Scientific and Technical Information (OSTI.GOV)

King, J.Y.; Lang, T.C.; Wei, H.J.

2007-07-01

The Fuel Cycle and Materials Administration (FCMA) in Taiwan announced a Supplementary Regulation for Classification of Low Radioactive Wastes, as well as the Regulation for Disposing of Low Radioactive Wastes and its Facility Safety Management in July 17, 1997, and September 10, 2003, respectively. The latter regulation states that in the future, before delivering low-level radioactive waste to a final land disposal site, each waste drum must specify the nuclide activity and be classified as class A, B, C or greater than C. The nuclide activity data for approximately 100,000 drums of low-level radwaste at the Lan-Yu temporary storage sitemore » accumulated in 1982-1995, therefore, must be established according to the above regulations. The original waste database at the Lan-Yu site indicates that the data were absent for about 9% and 72% of Co-60 and Cs-137 key nuclide activities, respectively. One of the principal tasks in this project was to perform whole drum gamma radioactivity analysis and contact dose rate counting to establish the relationship of dose-to-curie (D-to-C) of specific waste stream to derive gamma radioactivity of counting drums for 2 trenches repackaged at the Lan-Yu site. Utilizing regression function of Microsoft Excel and collected gamma data, a dose-to-curie relationship for the whole-drum radwaste is estimated in this study. Based on the relationship between radioactivity of various nuclides and the surface dose rate, an empirical function of the dose rate (Dose) associated with product of nuclide activity (Curie) and energy (Energy), CE is set up. Statistical data demonstrated that 838 whole drums were counted employing D-to-C approach to classify other 3,279 drums, and only the contact dose rate was detected for roughly 75% of the drums to estimate gamma radioactivity of whole drums, which can save considerable cost, time, and manpower. The 4,508 drums were classified as A and 7 drums as C after repackaging was complete. The estimation

Identification of post traumatic stress disorder and risk factors in military first responders 6 months after Wen Chuan earthquake in China.

PubMed

Wang, Huanlin; Jin, Hua; Nunnink, Sarah E; Guo, Wei; Sun, Jian; Shi, Jianan; Zhao, Bin; Bi, Yinhau; Yan, Tongjun; Yu, Haiying; Wang, Guangjian; Gao, Zhiqing; Zhao, Hanqing; Ou, Yanghui; Song, Zixiagn; Chen, Fangbin; Lohr, James B; Baker, Dewleen G

2011-04-01

Military personnel commonly serve as first responders to natural disasters. Our aim is to identify Post-Traumatic Stress Disorder (PTSD) and determine risk in military responders to the Wen Chuan earthquake. Analyses were carried out on 1056 of the 1125 soldiers enrolled. In addition to social demographic characteristics, the Davidson Trauma Scale (DTS) and an Earthquake exposure screening scale were administered. PTSD prevalence was 6.53% (69 cases). Logistic regression indicated that intensity of traumatic exposure (odds ratio 6.46, 95% CI 4.47-9.32, p<0.001), not having received psychological counseling (odds ratio 3.28, 95% CI 1.31-8.20, p<0.02) and regular drinking (odds ratio 2.42, 95% CI 1.04-5.62, p<0.05) were significant predictors of PTSD. Being a single-child, not being raised by both parents and regular smoking also independently predicted PTSD if intensity of earthquake traumatic exposure was not included in the model. The self-rated DTS was used to classify PTSD in this study and psychiatric co-morbidity outside of PTSD was not assessed in this sample. PTSD is a concern for Military disaster responders; to identify those with high risk of developing PTSD would be important and beneficial. Published by Elsevier B.V.

Neuroprotective effects and UPLC-Q-TOF/MS-based active components identification of external applied a novel Wen-Luo-Tong microemulsion.

PubMed

Lin, Hong-Mei; Lin, Long-Fei; Xia, Zhen-Zhen; Mao, Yong; Liu, Jia; Xu, Ling-Yan; Wu, Qing

2017-11-13

Chemotherapy induced neuropathy causes excruciating pain to cancer patients. Wen-Luo-Tong (WLT), a traditional Chinese medicinal compound, has been used to alleviate anti-cancer drug such as oxaliplatin-induced neuropathic pain for many years. However, the current route of administration of WLT is inconvenient and the active ingredients and mechanism of action of WLT are still unclear. To address these issues, we developed a novel formulation of WLT (W/O microemulsion) for the ease of application. New ultra-performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UPLC-Q-TOF/MS) methods were employed for analysis of the ingredients. We identified seven ingredients that penetrated through the skin into the Franz cell receptor solution and four of those ingredients were retained in skin tissue when WLT microemulsion was applied. We tested the microemulsion formulation on an oxaliplatin-induced neuropathy rat model and showed that this formulation significantly decreased oxaliplatin-induced mechanical hyperalgesia responses. Schwann cells (SCs) viability experiment in vitro was studied to test the protective effect of the identified seven ingredients. The result showed that Hydroxysafflor Yellow A, icariin, epimedin B and 4-dihydroxybenzoic acid significantly increased the viability of SCs after injured by Oxaliplatin. Our report presents the first novel formulation of WLT with neuroprotective effect and ease of use, which has potential for clinical applications.

[Temperature modifies the acute effect of particulate air pollution on mortality in Jiang'an district of Wuhan].

PubMed

Zhu, Y H; Wu, R; Zhong, P R; Zhu, C H; Ma, L

2016-06-01

To analyze the temperature modification effect on acute mortality due to particulate air pollution. Daily non-accidental mortality, cardiovascular mortality, and respiratory mortality data were obtained from Jiang'an District Center for Disease Control and Prevention. Daily meteorological data on mean temperature and relative humidity were collected from China Meteorological Data Sharing Service System. The daily concentration of particulate matter was collected from Wuhan Environmental Monitoring center. By using the stratified time-series models, we analyzed effects of particulate air pollution on mortality under different temperature zone from 2002 to 2010, meanwhile comparing the difference of age, gender and educational level, in Wuhan city of China. High temperature (daily average temperature > 33.4 ℃) obviously enhanced the effect of PM10 on mortality. With 10 μg/m(3) increase in PM10 concentrations, non-accidental, cardiovascular, and respiratory mortality increased 2.95% (95%CI: 1.68%-4.24%), 3.58% (95%CI: 1.72%-5.49%), and 5.07% (95%CI: 2.03%-9.51%) respectively. However, low temperature (daily average temperature <-0.21 ℃) enhanced PM10 effect on respiratory mortality with 3.31% (95% CI: 0.07%-6.64%) increase. At high temperature, PM10 had significantly stronger effect on non-accidental mortality of female aged over 65 and people with high educational level groups. With an increase of 10 μg/m(3), daily non-accidental mortality increased 4.27% (95% CI:2.45%-6.12%), 3.38% (95% CI:1.93%-4.86%) and 3.47% (95% CI:1.79%-5.18%), respectively. Whereas people with low educational level were more susceptible to low temperature. A 10 μg/m(3) increase in PM10 was associated with 2.11% (95% CI: 0.20%-4.04%) for non-accidental mortality. Temperature factor can modify the association between the PM10 level and cause-specific mortality. Moreover, the differences were apparent after considering the age, gender and education groups.

Focal Depth of the WenChuan Earthquake Aftershocks from modeling of Seismic Depth Phases

NASA Astrophysics Data System (ADS)

Luo, Y.; Zeng, X.; Chong, J.; Ni, S.; Chen, Y.

2008-12-01

After the 05/12/2008 great WenChuan earthquake in Sichuan Province of China, tens of thousands earthquakes occurred with hundreds of them stronger than M4. Those aftershocks provide valuable information about seismotectonics and rupture processes for the mainshock, particularly accurate spatial distribution of aftershocks is very informational for determining rupture fault planes. However focal depth can not be well resolved just with first arrivals recorded by relatively sparse network in Sichuan Province, therefore 3D seismicity distribution is difficult to obtain though horizontal location can be located with accuracy of 5km. Instead local/regional depth phases such as sPmP, sPn, sPL and teleseismic pP,sP are very sensitive to depth, and be readily modeled to determine depth with accuracy of 2km. With reference 1D velocity structure resolved from receiver functions and seismic refraction studies, local/regional depth phases such as sPmP, sPn and sPL are identified by comparing observed waveform with synthetic seismograms by generalized ray theory and reflectivity methods. For teleseismic depth phases well observed for M5.5 and stronger events, we developed an algorithm in inverting both depth and focal mechanism from P and SH waveforms. Also we employed the Cut and Paste (CAP) method developed by Zhao and Helmberger in modeling mechanism and depth with local waveforms, which constrains depth by fitting Pnl waveforms and the relative weight between surface wave and Pnl. After modeling all the depth phases for hundreds of events , we find that most of the M4 earthquakes occur between 2-18km depth, with aftershocks depth ranging 4-12km in the southern half of Longmenshan fault while aftershocks in the northern half featuring large depth range up to 18km. Therefore seismogenic zone in the northern segment is deeper as compared to the southern segment. All the aftershocks occur in upper crust, given that the Moho is deeper than 40km, or even 60km west of the

A taxonomic synopsis of Altingiaceae with nine new combinations

PubMed Central

Ickert-Bond, Stefanie M.; Wen, Jun

2013-01-01

Abstract A taxonomic synopsis of the Altingiaceae is presented, including the taxonomic enumeration and distribution of 15 recognized species based on studies of 1,500 specimens from 24 herbaria throughout the distributional range of the taxa. Previous phylogenetic analyses based on several molecular markers have shown that Altingia and Semiliquidambar are nested within Liquidambar. All Altingia and Semiliquidambar species are now formally transferred to Liquidambar, which has the nomenclatural priority. The following nine new combinations are herein made: Liquidambar cambodiana(Lecomte) Ickert-Bond & J. Wen, Liquidambar caudata (H. T. Chang) Ickert-Bond & J. Wen, Liquidambar chingii (Metcalf) Ickert-Bond & J. Wen, Liquidambar gracilipes (Hemsl.) Ickert-Bond & J. Wen, Liquidambar multinervis(Cheng) Ickert-Bond & J. Wen, Liquidambar obovata (Merrill & Chun) Ickert-Bond & J. Wen, Liquidambar poilanei (Tardieu) Ickert-Bond & J. Wen, Liquidambar siamensis (Craib) Ickert-Bond & J. Wen, and Liquidambar yunnanensis (Rehder & Wilson) Ickert-Bond & J. Wen. PMID:24399902

Water balance analysis of the Morava River floodplain in the Kostice-Lanžhot transect using the WBCM-7 model.

PubMed

Kovář, Pavel; Heřmanovská, Darina; Hadaš, Pavel; Hrabalíková, Michaela; Pešková, Jitka

2016-02-01

The study area of the Morava River floodplain is situated between the rivers Morava and Kyjovka in the reach from Hodonín to Lanžhot. This experimental area was chosen because during the last 30 years, there has been a serious problem with the frequent occurrence of hydrological extremes, such as floods and droughts. Dry seasons have a very negative impact on the floodplain forest and have been caused mainly by regulation of the Morava River channel in the 1970s. Since flooding in the catastrophic year 1977, a part of this area has served as a polder for flood impact mitigation of the urbanised area of the town of Lanžhot. Management and farming practices have been heavily affected by the enormous economic and ecological damage due to long-term flooding of agricultural land. The purpose of this study is to assess the extent to which the precipitation in the growing season of the dry years 2003 and 2011 was deficient, in comparison with the normal year 2009, through a study of the actual evapotranspiration caused by the significant drought in the Morava floodplain. A similar but converse situation in the wet year 2010 was also analysed, with the aim to show the differences in the components of the water balance equation in the growing seasons of all the extreme years tested here. The daily data from the Kostice climatological station were processed using the WBCM-7 model, where the input parameters were calibrated by the fluctuation of the groundwater table in the control borehole.

Spatial distribution and source apportionment of water pollution in different administrative zones of Wen-Rui-Tang (WRT) river watershed, China.

PubMed

Yang, Liping; Mei, Kun; Liu, Xingmei; Wu, Laosheng; Zhang, Minghua; Xu, Jianming; Wang, Fan

2013-08-01

Water quality degradation in river systems has caused great concerns all over the world. Identifying the spatial distribution and sources of water pollutants is the very first step for efficient water quality management. A set of water samples collected bimonthly at 12 monitoring sites in 2009 and 2010 were analyzed to determine the spatial distribution of critical parameters and to apportion the sources of pollutants in Wen-Rui-Tang (WRT) river watershed, near the East China Sea. The 12 monitoring sites were divided into three administrative zones of urban, suburban, and rural zones considering differences in land use and population density. Multivariate statistical methods [one-way analysis of variance, principal component analysis (PCA), and absolute principal component score-multiple linear regression (APCS-MLR) methods] were used to investigate the spatial distribution of water quality and to apportion the pollution sources. Results showed that most water quality parameters had no significant difference between the urban and suburban zones, whereas these two zones showed worse water quality than the rural zone. Based on PCA and APCS-MLR analysis, urban domestic sewage and commercial/service pollution, suburban domestic sewage along with fluorine point source pollution, and agricultural nonpoint source pollution with rural domestic sewage pollution were identified to the main pollution sources in urban, suburban, and rural zones, respectively. Understanding the water pollution characteristics of different administrative zones could put insights into effective water management policy-making especially in the area across various administrative zones.

Synopsis of Nekemias Raf., a segregate genus from Ampelopsis Michx. (Vitaceae) disjunct between eastern/southeastern Asia and eastern North America, with ten new combinations

PubMed Central

Wen, Jun; Boggan, John; Nie, Ze-Long

2014-01-01

Abstract The genus Nekemias (Vitaceae) was first recognized by Rafinesque in 1838. It has been treated as a synonym of Ampelopsis Michx. Recent phylogenetic studies suggest that Ampelopsis as traditionally delimited is paraphyletic. To maintain the monophyly of each of the genera of Vitaceae, we herein segregate the Ampelopsis sect. Leeaceifoliae lineage from Ampelopsis and recognize these taxa in Nekemias Raf., which has a disjunct distribution in eastern to southeastern Asia and eastern North America. Nomenclatural changes are made for nine species and one variety: Nekemias arborea (L.) J. Wen & Boggan, Nekemias cantoniensis (Hook. & Arn.) J. Wen & Z.L. Nie, Nekemias celebica (Suess.) J. Wen & Boggan, Nekemias chaffanjonii (H. Lév. & Van.) J. Wen & Z.L. Nie, Nekemias gongshanensis (C.L. Li) J. Wen & Z.L. Nie, Nekemias grossedentata (Hand.-Mazz.) J. Wen & Z.L. Nie, Nekemias hypoglauca (Hance) J. Wen & Z.L. Nie, Nekemias megalophylla (Diels & Gilg) J. Wen & Z.L. Nie, Nekemias megalophylla var. jiangxiensis (W.T. Wang) J. Wen & Z.L. Nie, and Nekemias rubifolia (Wall.) J. Wen & Z.L. Nie. A taxonomic key is provided for the genus to facilitate identification. PMID:25383008

Efficacy of the wen dan decoction, a Chinese herbal formula, for metabolic syndrome.

PubMed

Huang, Yan-Mei; Xu, Jia-Hua; Ling, Wei; Li, Yang; Zhang, Xiao-Xi; Dai, Zhi-Kai; Sui, Yi; Zhao, Hai-Lu

2015-01-01

Metabolic syndrome (MS) refers to the clustering of metabolic derangements that include hyperglycemia, dyslipidemia, hypertension, and chronic kidney impairment. Those conditions are well known as being synergistically responsible for morbidity from cardiovascular disease as well as for driving the global epidemic of type 2 diabetes. It is still unknown whether an exact unifying pathogenesis of MS exists. The meta-analysis intended to analyze the use of Chinese medicine (CM) as a therapeutic tool to explore indirectly the unifying pathogenesis of MS. PubMed, the Chinese National Knowledge Infrastructure (CNKI), and the Wanfang databases were systematically searched from inception to November 2013 for randomized, controlled trials (RCTs) that compared treatment efficacy for MS patients using the Wen Dan decoction (WDD), a CM formula, versus Western conventional therapeutics. Measurements included tests of the overall therapeutic efficacy of WDD for hyperglycemia, hypertension, dyslipidemia, and renal functions, and the study also analyzed adverse events. Data were expressed as weighted mean differences (WMDs), with 95% confidence intervals (95% CIs) and the odds ratio (OR). A total of 31 RCTs were included for meta-analysis, involving 2512 patients and including 1282 participants in the intervention groups. The pooled data favored WDD over the control treatments as follows: (1) hyperglycemia, with a WMD of -0.95 mmol/L (95% CI: -1.19 to -0.71); (2) hypertension, with a WMD of -7.40 mm Hg (95% CI: -9.86 to -4.93); (3) dyslipidemia: (a) total cholesterol (TC), with a WMD of -0.62 mmol/L (95% CI: -0.90 to -0.33); (b) triglycerides (TGs), with a WMD of -0.32 mmol/L (95% CI: -0.52 to -0.13); (c) low-density lipoproteins (LDPs), with a WMD of -0.22 mmol/L (95% CI: -0.41 to -0.02); and (d) high-density lipoproteins (HDPs), with a WMD of 0.10 mmol/L (95% CI: 0.03 to 0.17); and (4) of renal functions: (a) urea, with a WMD of -3.41 mmol/L (95% CI: -5.50 to -1.32) and (b

Exposure of the general public due to wireless LAN applications in public places.

PubMed

Schmid, G; Preiner, P; Lager, D; Uberbacher, R; Georg, R

2007-01-01

The typical exposure caused by wireless LAN applications in public areas has been investigated in a variety of scenarios. Small-sized (internet café) and large-scale (airport) indoor scenarios as well as outdoor scenarios in the environment of access points (AP) supplying for residential areas and public places were considered. The exposure assessment was carried out by numerical GTD/UTD computations based on optical wave propagation, as well as by verifying frequency selective measurements in the considered scenarios under real life conditions. In the small-sized indoor scenario the maximum temporal peak values of power density, spatially averaged over body dimensions, were found to be lower than 20 mW/m(2), corresponding to 0.2% of the reference level according to the European Council Recommendation 1999/519/EC. Local peak values of power density might be 1-2 orders of magnitude higher, spatial and time-averaged values for usual data traffic conditions might be 2-3 orders of magnitude lower, depending on the actual data traffic. In the considered outdoor scenarios, exposure was several orders of magnitude lower than in indoor scenarios due to the usually larger distances to the AP antennas.

137,138,139La(n ,γ ) cross sections constrained with statistical decay properties of 138,139,140La nuclei

NASA Astrophysics Data System (ADS)

Kheswa, B. V.; Wiedeking, M.; Brown, J. A.; Larsen, A. C.; Goriely, S.; Guttormsen, M.; Bello Garrote, F. L.; Bernstein, L. A.; Bleuel, D. L.; Eriksen, T. K.; Giacoppo, F.; Görgen, A.; Goldblum, B. L.; Hagen, T. W.; Koehler, P. E.; Klintefjord, M.; Malatji, K. L.; Midtbø, J. E.; Nyhus, H. T.; Papka, P.; Renstrøm, T.; Rose, S. J.; Sahin, E.; Siem, S.; Tornyi, T. G.

2017-04-01

The nuclear level densities and γ -ray strength functions of 138,139,140La were measured using the 139La(3He,α ), 139La(3He,3He' ), and 139La(d ,p ) reactions. The particle-γ coincidences were recorded with the silicon particle telescope (SiRi) and NaI(Tl) (CACTUS) arrays. In the context of these experimental results, the low-energy enhancement in the A ˜140 region is discussed. The 137,138,139La (n ,γ ) cross sections were calculated at s - and p -process temperatures using the experimentally measured nuclear level densities and γ -ray strength functions. Good agreement is found between 139La(n ,γ ) calculated cross sections and previous measurements.

The effectiveness of a popular science promotion program on nanotechnology for elementary school students in I-Lan City

NASA Astrophysics Data System (ADS)

Lin, Show-Yu; Wu, Ming-Ta; Cho, Ya-I.; Chen, Hui-Huang

2015-01-01

Background:Nanotechnology education has become an urgent priority to nurture skilled human resources for the rapidly developing nanotechnology-related industries. The promotion of popular science education focusing on nanotechnology is an ideal approach to bridge the gaps in formal curricula, and to stimulate curiosity about and interest in nanotechnology among schoolchildren. Purpose:The objective of this study was to evaluate the effectiveness of the Nanotechnology-based Popular Science Education Promotion and Teaching (NPSEPT) program through camp activity that was implemented in elementary schools in I-Lan City, Taiwan. Program description:To create a competitive advantage, a human resources development program was implemented as one of the nanotechnology incubation projects in Taiwan and focused on developing an appropriately-skilled professional workforce as well as promoting popular science education. Sample:The volunteer research participants were 323 sixth grade students in four elementary schools in I-Lan City, Taiwan, who were evaluated at the beginning and the end of the nanotechnology-based popular science promotion camp activity. Design and methods:A research tool called the 'NPSEPT test' was designed specifically for this study and was approved by experts who evaluated its content and face validity. The questionnaire was divided into three aspects: 'Nanophenomena in the natural world'; 'Nanomaterials and their scaling effects'; and 'Definition, characteristics, and applications of nanotechnology.' The effectiveness of learning among the students was analyzed using descriptive statistics, a paired sample t-test, analysis of variance (ANOVA) and a post hoc comparison. Results:The results of the three-part 'NPSEPT test' revealed that NPSEPT significantly advanced nanotechnology learning performance and outcomes among students in the four participating elementary schools. Of the 15 questions included in the NPSEPT test, positive change for more than 30

[Relationship between leaf anatomical structure and heat resistance of 15 Rhododendron cultivars].

PubMed

Shen, Hui Fei; Zhao, Bing; Xu, Jing Jing

2016-12-01

In this study, 17 anatomical structure indexes of 15 Rhododendron cultivars were mea-sured by scanning electron microscope (SEM). Leaf anatomical structure indexes were screened via coefficient of variation, analysis of correlation and hierarchical cluster analysis, and comprehensive evaluation on heat resistance for each cultivar was conducted by the subordinate function. The results showed that the leaves of Rhododendron cultivars were typical bifacial leaf and the epidermal anticlinal walls showed slightly sinuate. The stomata only distributed in the lower epidermis and the shape was ruleless. The anatomical structure indexes all reached a significant level difference among 15 cultivars (P<0.01), except for lower epidermis thickness (P<0.05). Thickness of lamina corneum, stomatal density, stomatal width, the thickness palisade tissue and looseness of leaf spongy tissue were the main factors related to the hardness, while other indexes, such as stomatal length, stoma aperture, stomatal opening, length and thickness of upper epidermis, length and thickness of lower epidermis, thickness of spongy tissue, the ratio of the palisade tissue to spongy tissue, tightness of leaf palisade tissue, leaf thickness and media thickness didn't show much effect on heat resistance. There were some differences among 15 cultivars in heat resistance, and the order was Rhododendron 'Song Jiang Da Tao Hong' > Rhododendron 'Zhuang Yuan Hong' > Rhododendron 'Lv Se Guang Hui' > Rhododendron 'Fen Zhen Zhu' > Rhododendron 'Wai Guo Hong' > Rhododendron 'Lan Yin' > Rhododendron 'Bi Zhi' >Rhododendron 'Da He Zhi Chun' > Rhododendron 'Guo Qi Hong' > Rhododendron 'Yu Ling Long' > Rhododendron 'Hong Shan Hu' > Rhododendron 'Ning Bo Hong' > Rhododendron 'Tao Ban Zhu Sha' > Rhododendron 'Ai Ding Bao' > Rhododendron 'Liu Qiu Hong'. According to the heat hardiness, the cultivars could be divided into 4 groups: R. 'Song Jiang Da Tao Hong', R. 'Zhuang Yuan Hong' and R. 'Lv Se Guang Hui' with high heat

2008 Wen-Chuan Mw 8.3 Earthquake: Dynamic Deformation Analysis for Seismic Surface Waveforms with 1-Hz GPS PPP Results

NASA Astrophysics Data System (ADS)

Shi, C.; Lou, Y.; Zhang, H.; Zhao, Q.; Liu, J.

2008-12-01

Some 1-Hz GPS data in China during Sichuan Wen-Chuan Mw8.3 Earthquake are processed with instantaneous Precise Point Positioning (PPP) technique using software PANDA developed in Wuhan University. Near-field GPS stations are located 30km away but lost data after 10s while several far-field sites are 300km~1200km away from epicenter. Results indicate that plane displacements exceed 40cm within 10seconds in near field while the post-seismic deformation is northwestward at the magnitude of around 30cm. Seismic surface waveforms as LOVE and Rayleigh waves can be seen clearly in the dynamic deformation process of station XANY and CHGO (in KunMing city, Yunnan Province). Love wave's first vibration is in northwestward and then southeastward, after about one cycle, Rayleigh wave comes. Love wave is at the speed of about 4km/s, Rayleigh's is about 2.85km/s. There are two deformation pulses in Rayleigh waveforms during the period of about 120 seconds monitored at station XANY, which is about 600km from epicenter. One pulse is in counter-clockwise movement and the other is clock-wise, which seems to reveal the fact that there are two kinds of rupture process in totally opposite direction. Spectral analysis shows that there are mainly two kinds of periods in the surface waves reflected by the 1-Hz horizontal deformations, one is about 5~10s (6s and 8s) and another is about 20s, corresponding to Rayleigh and Love wave respectively. Rayleigh's wavelength is about 20km, which indicates that the hypocenter is about in the depth of 10km.

Coupled geohazards at Southern Andes (Copahue-Lanín volcanoes): Chile's GEO supersite proposal

NASA Astrophysics Data System (ADS)

Lara, Luis E.; Cordova, Loreto

2017-04-01

Southern Andes are a young and active mountain belt where volcanism and tectonic processes (and those related to the hydrometeorological conditions controlled by this geological setting) pose a significant threat to the growing communities nearby. This proposal focus on a ca. 200 km long segment of the Southern Andes where 9 stratovolcanoes and 2 distributed volcanic fields are located, just along a tectonic corridor defined by the northern segment of the Liquiñe-Ofqui Faul System (LOFS), a long-lived active strike-slip fault running for 1200 km. Volcanoes in this area take part of the central province of the Andean Southern Volcanic Zone (37-41°S), particularly the northermost portion that is limited at the south by an Andean tranverse fault (Lanalhue Fault, which define the Villarrica-Lanin volcanic chain) and run along the horse-tail array of the LOFS to the north. Most of the stravolcanoes are atop of the LOFS main branch with only 3 exceptions (Callaqui, Tolhuaca and Lanín) 15-20 km away, but related to transverse faults. Hazards in the segment derive from the activity of some of the most active volcanoes in South America (e.g., Villarrica, Llaima), others with long-lasting weak activity (e.g., Copahue) or some volcanoes with low frequency but high magnitude eruptions in the geological record. Only since the beggining of the 20th century 80 eruptions have been recorded in this area. In addition, activity of the LOFS has been detected prior to some eruptions and coeval with some others (e.g., Lonquimay 1989). A strong two-way coupling between tectonics and volcanism has been proposed for the segment but only recently detected by geophysical techniques or numerical modelling. Tectonic triggered landslides are frequent in this region together with debris flows at erupting ice-covered volcanoes or stream headed at high altitude basins. The latter scenario seems to be worst at present because of global climate change. Ground-based monitoring networks for both

Combine bivariate statistics analysis and multivariate statistics analysis to assess landslide susceptibility in Chen-Yu-Lan watershed, Nantou, Taiwan.

NASA Astrophysics Data System (ADS)

Ngan Nguyen, Thi To; Liu, Cheng-Chien

2013-04-01

How landslides occurred and which factors triggered and sped up landslide occurrences were usually asked by researchers in the past decades. Many investigations carried out in many places in the world to finding out methods that predict and prevent damages from landslides phenomena. Chen-Yu-Lan River watershed is reputed as a 'hot pot' of landslide researches in Taiwan by its complicated geological structures with the significant tectonic fault systems and steeply mountainous terrain. Beside annual high precipitation concentration and the abrupt slopes, some natural disaster, as typhoons (Sinlaku-2008, Kalmaegi-2008, and Marakot-2009) and earthquake (Chi-Chi earthquake-1999) are also the triggered factors cause landslides with serious damages in this place. This research expresses the quantitative approaches to generate landslide susceptible map for Chen-Yu-Lan watershed, a mountainous area in the central Taiwan. Landslide inventories data, which were detected from the Formosat-2 imageries for eight years from 2004 to 2011, were applied to carry out landslide susceptibility mapping. Bivariate statistics analysis and multivariate statistics analysis would be applied to calculate susceptible index of landslides. The weights of parameters were computed based on landslide data for eight years from 2004 to 2011. To validate effective levels of factors to landslide occurrences, this method built some multivariate algorithms and compared these results with real landslide occurrences. Besides this method, the historical data of landslides were also used to assess and classify landslide susceptibility levels. From long-term landslide data, relation between landslide susceptibility levels and landslide repetition was assigned. The results demonstrated differently effective levels of potential factors, such as, slope gradient, drainage density, lithology and land use to landslide phenomena. The results also showed logical relationship between weights and characteristics of

Electronic structure of the ingredient planes of Bi2Sr2CaCu2O8 + δ and Bi2Sr2CuO6 + δ superconductors

NASA Astrophysics Data System (ADS)

Ma, Xucun

Understanding the mechanism of high transition temperature superconductivity in cuprates has been hindered by the apparent complexity of their multilayered crystal structure. Using a cryogenic scanning tunneling microscopy (STM), we report on layer-by-layer probing of the electronic structures of the ingredient planes (BiO, SrO, CuO2) of Bi2Sr2CaCu2O8 + δ (Bi-2212) and Bi2Sr2CuO6 + δ (Bi-2201) superconductors prepared by argon-ion bombardment and annealing (IBA) technique. We show that the well-known pseudogap (PG) feature observed by STM is inherently a property of the charge reservoir planes and thus irrelevant directly to Cooper pairing. The CuO2 planes are exclusively characterized by a small gap inside the PG. The small gap becomes invisible near Tc, which we identify as the superconducting gap. The results constitute severe constraints on any microscopic model for high Tc superconductivity in cuprates. Contributors: Yan-Feng Lv, Wen-Lin Wang, Hao Ding, Yang Wang, Yong Zhong, Ying Ding, Ruidan Zhong, John Schneeloch, Gen-Da Gu, Lili Wang, Ke He, Shuai-Hua Ji, Lin Zhao, Xing-Jiang Zhou Can-Li Song, and Qi-Kun Xue. NSF and MOST of China.

Revision of the Maddenia clade of Prunus (Rosaceae)

PubMed Central

Wen, Jun; Shi, Wenting

2012-01-01

Abstract The Maddenia clade of Prunus L. is monographed based on herbarium and field studies. Four species are currently accepted in this group: Prunus himalayana J.Wen, Prunus hypoleuca (Koehne) J.Wen, Prunus hypoxantha (Koehne) J.Wen, and Prunus gongshanensis J.Wen, with the last described herein as a new species. Maddenia fujianensis Y.T.Chang and Maddenia incisoserrata T.T.Yü & T.C.Ku are treated as synonyms of Prunus hypoleuca. PMID:22577333

Chun-Sheng Jiang | NREL

Science.gov Websites

photovoltaic and energy storage technologies. He has conducted pioneer nanometer-scale characterization for photovoltaic technology by developing and applying SPM-based nanoelectrical probes of Kelvin probe force ). These characterizations involve a wide range of photovoltaic materials and devices including organic

VizieR Online Data Catalog: A Finding List of Faint UV-Bright Stars (Lanning+, 1998)

NASA Astrophysics Data System (ADS)

Lanning, H. H.

1997-02-01

The Sandage two-color photographic survey was originally made in support of the UHURU x-ray satellite in order to identify those optical counterparts of the detected x-ray sources found in the galactic plane. During inspection of the plates, however, many UV-bright objects fainter than 10th magnitude were seen in the general field. A larger image in the U filter suggested the possibility of a bluer object as in the case of low-luminosity stars, white dwarfs, novae, CVs, normal early B stars, etc. As these are interesting in themselves, it was decided to publish a catalog for the use of other observers. This multi-color photographic technique has been described, for example, by Haro and Herbig (1955). The survey was concentrated on objects with m(B)~10 or fainter. It employed the Palomar 48-in (Oschin) Schmidt telescope and was centered on the galactic plane with overlapping regions covering the galactic latitudes +- 9 degrees, and extending throughout most of the northern plane (l = 0 deg - 227 deg). Plates were taken by J. Kristian, A.R. Sandage, R.J. Brucato, and Lanning, primarily. The data presented here were found following a careful examination of the plates but it should not be assumed these data represent a complete survey of the fields examined. The categories were roughly calibrated against photoelectric (U-B) measures, but a full scale calibration program, including magnitude effects, etc. was not done. The numerical (U-B) limits of the tables should not therefore be taken precisely. The blue magnitude of the sources in the finding list has been estimated using these photoelectric values as a guide but should be considered accurate to only +- 0.5 mag. due to the difficulty of adjusting to the various plate characteristics. Positions were measured from images retrieved from the Space Telescope Science Institute collection of Guide Star digital plate scans. The accuracy of positions from the Guide Star Catalog images has been estimated to be on the order

Lipid-lowering and antioxidant activities of Jiang-Zhi-Ning in Traditional Chinese Medicine.

PubMed

Chen, Jianxin; Zhao, Huihui; Yang, Ying; Liu, Bing; Ni, Jian; Wang, Wei

2011-04-12

Jiang-Zhi-Ning (JZN) is composed of four Chinese herbs, i.e., Fleeceflower Root, Fructus Crataegi, Folium Nelumbinis and Semen Cassiae. It was used to strengthen blood circulation of coronary artery, arrhythmia and hyperlipidemia. The main objective of this paper is to evaluate lipid-lowering and antioxidant activities of extract and effective fraction of JZN by using in vitro experiments on hyperlipidemic rats. Moreover, in vivo experiments on cells were performed to investigate lipid-lowering and antioxidant activities of effective fraction and active constituents of JZN. Wistar rats with high fat diet-induced hyperlipidemia were used as in vitro models to study biological effects of lipid-lowering and antioxidant activities of extract and effective fraction of JZN. Serum total cholesterol (TC), triglyceride (TG), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), Coronary Index and Atherogenic Index were investigated to evaluate lipid-lowering effects of extract and effective fraction of JZN. Serum total nitric oxide synthase (NOS), nitric oxide (NO), endothelin-1 (ET-1), malondialdehyde (MDA), superoxide dismutase (SOD) and total antioxidant capacity (T-AOC) were detected to measure antioxidant effects of extract and effective fraction of JZN. Furthermore, oxidized low-density lipoprotein (Ox-LDL) injured human umbilical vein endothelial cell (HUVEC) model was employed as in vivo experiment to study lipid-lowering and antioxidant effects of effective fraction and active constituents of JZN. NO, ET-1, MDA SOD and T-AOC in HUVECs or culture media were investigated to evaluate antioxidant activity of effective fraction and active constituents of JZN. Using human hepatoma cell line Bel-7402, reverse transcription polymerase chain reaction (RT-PCR) technology was performed to investigate cholesterol metabolism effects of effective fraction and active constituents of JZN. Expressions of low density lipoprotein receptor (LDL

Satellite-derived land covers for runoff estimation using SCS-CN method in Chen-You-Lan Watershed, Taiwan

NASA Astrophysics Data System (ADS)

Zhang, Wen-Yan; Lin, Chao-Yuan

2017-04-01

The Soil Conservation Service Curve Number (SCS-CN) method, which was originally developed by the USDA Natural Resources Conservation Service, is widely used to estimate direct runoff volume from rainfall. The runoff Curve Number (CN) parameter is based on the hydrologic soil group and land use factors. In Taiwan, the national land use maps were interpreted from aerial photos in 1995 and 2008. Rapid updating of post-disaster land use map is limited due to the high cost of production, so the classification of satellite images is the alternative method to obtain the land use map. In this study, Normalized Difference Vegetation Index (NDVI) in Chen-You-Lan Watershed was derived from dry and wet season of Landsat imageries during 2003 - 2008. Land covers were interpreted from mean value and standard deviation of NDVI and were categorized into 4 groups i.e. forest, grassland, agriculture and bare land. Then, the runoff volume of typhoon events during 2005 - 2009 were estimated using SCS-CN method and verified with the measured runoff data. The result showed that the model efficiency coefficient is 90.77%. Therefore, estimating runoff by using the land cover map classified from satellite images is practicable.

JiangTang XiaoKe granule attenuates cathepsin K expression and improves IGF-1 expression in the bone of high fat diet induced KK-Ay diabetic mice.

PubMed

Guo, Yubo; Wang, Lili; Ma, Rufeng; Mu, Qianqian; Yu, Na; Zhang, Yi; Tang, Yuqing; Li, Yu; Jiang, Guangjian; Zhao, Dandan; Mo, Fangfang; Gao, Sihua; Yang, Meijuan; Kan, Feifei; Ma, Qun; Fu, Min; Zhang, Dongwei

2016-03-01

To assess the beneficial effects of JiangTang XiaoKe (JTXK) granule on the bone metabolism in high fat diet (HFD) fed KK-Ay diabetic mice. The KK-Ay mice were used as a diabetic model, while C57BL/6 mice were utilized as the non-diabetic control. The left tibia was used for determining bone mineral density (BMD) and bone ash coefficient. The HE and alizarin red S staining of femur were employed to evaluate bone pathology and calcium deposition. The expressions of alkaline phosphatase (ALP), insulin growth factor 1 (IGF-1) and cathepsin K were assessed by western blotting and immunohistochemical staining. JTXK granule significantly improved the bone ash coefficient, the distribution of trabecular bone and the calcification nodules deposition in KK-Ay mice with diabetes. IGF-1 and ALP expressions were significantly decreased, and cathepsin K expression was dramatically increased in the HFD fed KK-Ay diabetic model mice, which can be reversed by JTXK granule treatment. JTXK granule at medium or high dosage was more efficient in improving diabetic bone quality when compared with that in mice with a low dosage. However, the BMD values in each group of KK-Ay diabetic mice were not significantly different. We demonstrate that cathepsin K expression is increased in KK-Ay diabetic mouse model. JTXK granule treatment inhibits osteoclastic bone resorption and promotes the new bone formation by decreasing cathepsin K activity and increasing IGF-1 and ALP levels. These changes may contribute to the increase of bone strength and thus reducing the risk of bone fractures. Copyright © 2016 Elsevier Inc. All rights reserved.

Implicit Learning of Complex Visual Contexts Under Non-Optimal Conditions

DTIC Science & Technology

2007-07-27

Perception & Performance, 31(6), 1439-1448. 3. Jiang Y, Song J-H, Rigas A (2005). High-capacity spatial contextual memory. Psychonomic Bulletin & Review , 12...Makovski T., & Jiang YV (in press). Distributing versus focusing attention in visual short-term memory. Psychonomic Bulletin & Review . 8. Rausei V...Implicit learning of ignored visual context. Psychonomic Bulletin & Review , 12(1), 100-106. Jiang, Y. H., & Song, J. H. (2005). Spatial context

Risk analysis of heavy metal concentration in surface waters across the rural-urban interface of the Wen-Rui Tang River, China.

PubMed

Qu, Liyin; Huang, Hong; Xia, Fang; Liu, Yuanyuan; Dahlgren, Randy A; Zhang, Minghua; Mei, Kun

2018-06-01

Heavy metal pollution is a major concern in China because of its serious effects on human health. To assess potential human health and ecological risks of heavy metal pollution, concentration data for seven heavy metals (As, Pb, Cd, Cr, Hg, Cu, Zn) from 14 sites spanning the rural-urban interface of the Wen-Rui Tang River watershed in southeast China were collected from 2000 to 2010. The heavy metal pollution index (HPI), hazard index (HI) and carcinogenic risk (CR) metrics were used to assess potential heavy metal risks. Further, we evaluated the uncertainty associated with the risk assessment indices using Monte Carlo analysis. Results indicated that all HPI values were lower than the critical level of 100 suggesting that heavy metal levels posed acceptable ecological risks; however, one site having an industrial point-source input reached levels of 80-97 on several occasions. Heavy metal concentrations fluctuated over time, and the decrease after 2007 is due to increased wastewater collection. The HI suggested low non-carcinogenic risk throughout the study period (HI < 1); however, nine sites showed CR values above the acceptable level of 10 -4 for potential cancer risk from arsenic in the early 2000s. Uncertainty analysis revealed an exposure risk for As at all sites because some CR values exceeded the 10 -4 level of concern; levels of Cd near an old industrial area also exceeded the Cd exposure standard (2.6% of CR values > 10 -4 ). While most metrics for human health risk did not exceed critical values for heavy metals, there is still a potential human health risk from chronic exposure to low heavy metal concentrations due to long-term exposure and potential metal interactions. Results of this study inform water pollution remediation and management efforts designed to protect public health in polluted urban area waterways common in rapidly developing regions. Copyright © 2018 Elsevier Ltd. All rights reserved.

DCIS-Specific MicroRNA in Cancer Stem Cell

DTIC Science & Technology

2011-09-01

Gairani, Misako Watabe, Fei Xing, Aya Kobayashi, Wen Liu, Koji Fukuda, , Sudha Pai and Kounosuke Watabe. Roles of lipogenesis and microRNA in cancer...Pai, Wen Liu, Aya Kobayashi, Fei Xing, Koji Fukuda , Shigeru Hirota, Tamotsu Sugai, Go Wakabayashi, Keisuke Koeda, Masahiro Kashiwaba, Kazuyuki...Aya Kobayashi, Wen Liu, Koji Fukuda, , Sudha Pai and Kounosuke Watabe Roles of lipogenesis and microRNA in cancer stem- like cells in ductal carcinoma

Aralia elata var. mandshurica (Rupr. & Maxim.) J.Wen: An overview of pharmacological studies.

PubMed

Shikov, Alexander N; Pozharitskaya, Olga N; Makarov, Valery G

2016-11-15

Aralia elata var. mandshurica (Rupr. & Maxim.) J.Wen syn. A. mandshurica Rupr. & Maxim is evaluated for its medicinal application. The aim of this study is to analyze pharmacological studies on A. elata var. mandshurica published until December 2015. The information regarding the chemistry, safety, effectiveness, and pharmacological and clinical effects of A. elata was systematically collected from the scientific literature through library catalogs; online services such as E-library.ru, Medline/PubMed, Scopus, Web of Science, and Google Scholar. A. elata is often considered an example of a medicinal plant used in Chinese, Korean, and Japanese traditional medicine. However, the contemporary applications of Aralia in officinal medicine result primarily from a large number of pharmacological and clinical investigations carried out in the former USSR in the mid-20th century. Since the 1950s, medicinal preparations from radices of A. elata and radices of A. mandshurica have secured an established position within Russian/USSR medicine as evidenced by the inclusion of the drug in recent editions of the National Pharmacopoeia of the USSR and in the Register of Medicinal Preparations of Russia. Pharmacological studies on animals have shown that Aralia increases physical working capacity and affords a stress-protective effect against a broad spectrum of harmful factors including cold stress, immobilization, UV irradiation, and low air pressure. The phytoadaptogen exerts an effect on the central nervous, reproductive, immune, respiratory, and gastrointestinal systems; the metabolic syndrome including hypolipidemic and antidiabetic effects; and blood coagulation. Together with general properties of adaptogens, Aralia has its own specificity, which manifests in cardioprotective and antiarrhythmic activities. Studies on isolated organs, cells, and enzymes have revealed that Aralia preparations exhibit antioxidant activities and enhance sarcoplasmic reticulum Ca 2+ -ATPase

Wavelet evolutionary network for complex-constrained portfolio rebalancing

NASA Astrophysics Data System (ADS)

Suganya, N. C.; Vijayalakshmi Pai, G. A.

2012-07-01

Portfolio rebalancing problem deals with resetting the proportion of different assets in a portfolio with respect to changing market conditions. The constraints included in the portfolio rebalancing problem are basic, cardinality, bounding, class and proportional transaction cost. In this study, a new heuristic algorithm named wavelet evolutionary network (WEN) is proposed for the solution of complex-constrained portfolio rebalancing problem. Initially, the empirical covariance matrix, one of the key inputs to the problem, is estimated using the wavelet shrinkage denoising technique to obtain better optimal portfolios. Secondly, the complex cardinality constraint is eliminated using k-means cluster analysis. Finally, WEN strategy with logical procedures is employed to find the initial proportion of investment in portfolio of assets and also rebalance them after certain period. Experimental studies of WEN are undertaken on Bombay Stock Exchange, India (BSE200 index, period: July 2001-July 2006) and Tokyo Stock Exchange, Japan (Nikkei225 index, period: March 2002-March 2007) data sets. The result obtained using WEN is compared with the only existing counterpart named Hopfield evolutionary network (HEN) strategy and also verifies that WEN performs better than HEN. In addition, different performance metrics and data envelopment analysis are carried out to prove the robustness and efficiency of WEN over HEN strategy.

Next Generation, Si-Compatible Materials and Devices in the Si-Ge-Sn System

DTIC Science & Technology

2015-10-09

AFOSR support: Richard Beeler (currently at Intel), Liying Jiang (currently at IBM), Gordon Grzybowski (currently at Wright Patterson AFB) and Chi ( Seth ...approaches to Si integration” J. Kouvetakis, A.V.G Chizmeshya, T. Watkins , G. Grzybowski, L. Jiang, R.T. Beleer, and J. Menéndez, Chemistry of...A.V.G Chizmeshya, T. Watkins , G. Grzybowski, L. Jiang, R.T. Beleer, and J. Menéndez, Chemistry of Materials 24(16), 3219-3230 (2012). [12

Predicting Rediated Noise With Power Flow Finite Element Analysis

DTIC Science & Technology

2007-02-01

Defence R&D Canada – Atlantic DEFENCE DÉFENSE & Predicting Rediated Noise With Power Flow Finite Element Analysis D. Brennan T.S. Koko L. Jiang J...PREDICTING RADIATED NOISE WITH POWER FLOW FINITE ELEMENT ANALYSIS D.P. Brennan T.S. Koko L. Jiang J.C. Wallace Martec Limited Martec Limited...model- or full-scale data before it is available for general use. Brennan, D.P., Koko , T.S., Jiang, L., Wallace, J.C. 2007. Predicting Radiated

Observations of Hydrocarbons and Halocarbons during ACE-Asia

NASA Astrophysics Data System (ADS)

Chen, T.; Chou, S.; Yeh, C.; Kai, F.; Wang, J.; Liu, S. C.

2001-12-01

Sixty hydrocarbons (HCs), 21 halocarbons and 7 alkyl nitrates were measured in 1322 whole air samples collected aboard the National Center for Atmospheric Research (NCAR) C-130 aircraft as part of NSF¡œs Asian Pacific Regional Aerosol Characterization Experiment (ACE-Asia). Thirty flights were flown from March to May, 2001, 19 of which were deployed from the Iwakuni airbase in southern Japan. These flights over the Yellow Sea, Sea of Japan, and the East China Sea, at a time when continental outflow was at its strongest, offered excellent opportunity to study the impact of Asian aerosol on the chemical and radiative properties of the Earth¡œs atmosphere. In addition, samples were collected at the two Taiwanese ground stations. Seventy four nearly daily samples were collected at Lan-Yu (2/28-5/15), and another 57 collected at Wen-Li (3/20-5/15). These additional data allows assessment of the impact of continental aerosol upon Pacific rim countries. Very high levels of aerosol were encountered on a number of flights, some dominated by dust, some by pollutants, and others a mixture of both. Elevated levels of hydrocarbons and halocarbons were observed in some of these plumes, suggesting inputs from urban industrial regions, and carried these anthropogenic pollutants out to the western Pacific basin. Many urban plumes were intercepted near their sources and the chemical signatures of these emitted anthropogenic pollutants varied greatly. These unique source signatures enable characterization of these high aerosol plumes and suggest possible paths of the outflow. In one particular example, a large dust storm was intercepted by the C-130 over the Yellow Sea on April 11, and on April 12, the same system reached Taiwan. Our data collected from the C-130 and the two Taiwanese ground stations allows comparison between these two air masses and assess its impact on the local air quality.

NITROTYROSINATION OF A TUBULIN INDUCES EPITHELIAL BARRIER DYSFUNCTION

EPA Science Inventory

Nitrotyrosination of a-Tubulin Induces Epithelial Transport Dysfunction. Yuh-Chin Huang, Lisa Dailey, Wen-Li Zhang and Ilona Jaspers. ORD, Environmental Protection Agency and CEMLB, University of North Carolina

a-Tubulin undergoes a cyclic removal and readdition of tyrosin...

Direct Broad-Range Detection of Alphaviruses in Mosquito Extracts

DTIC Science & Technology

2007-11-25

D.J., Robbins, D.W., Hannis , J.C., Harrell, P.M., Massire, C., Hall, T.A., Jiang, Y., Ranken, R., Drader, J.J., White, N., McNeil, J.A., Crooke, S.T...962. Hofstadler, S.A., Sampath, R., Blyn, L.B., Eshoo, M.W., Hall, T.A., Jiang, Y., Drader, J.J., Hannis , J.C., Sannes-Lowery, K.A., Cummins, L.L...H., Hannis , J., Harrell, P.M., Neuman, B., Buchmeier, M.J., Jiang, Y., Ranken, R., Drader, J., Samant, V., Griffey, R.H., McNeil, J.A., Crooke, S.T

WenTong HuoXue Cream Can Inhibit the Reduction of the Pain-Related Molecule PLC-β3 in the Dorsal Root Ganglion of a Rat Model of Diabetic Peripheral Neuropathy

PubMed Central

Feng, Chengcheng; Xu, Lijuan; Guo, Shiyun; Chen, Qian; Shen, Yuguo; Zang, Deng

2018-01-01

WenTong HuoXue Cream (WTHX-Cream) has been shown to effectively alleviate clinical symptoms of diabetic peripheral neuropathy (DPN). This study investigated the gene and protein expression of the pain-related molecule PLC-β3 in the dorsal root ganglion (DRG) of DPN rats. 88 specific pathogen-free male Wistar rats were randomly divided into placebo (10 rats) and DPN model (78 rats) groups, and the 78 model rats were used to establish the DPN model by intraperitoneal injection of streptozotocin and were then fed a high-fat diet for 8 weeks. These rats were randomly divided into the model group, the high-, medium-, and low-dose WTHX-Cream + metformin groups, the metformin group, the capsaicin cream group, and the capsaicin cream + metformin group. After 4 weeks of continuous drug administration, the blood glucose, body weight, behavioral indexes, and sciatic nerve conduction velocity were measured. The pathological structure of the DRG and the sciatic nerve were observed. PLC-β3 mRNA and protein levels in the DRG of rats were measured. Compared with the model group, the high-dose WTHX-Cream group showed increased sciatic nerve conduction velocity, improved sciatic nerve morphological changes, and increased expression of PLC-β3 mRNA and protein in the DRG. This study showed that WTHX-Cream improves hyperalgesia symptoms of DPN by inhibiting the reduction of PLC-β3 mRNA and protein expression in the diabetic DRG of DPN rats. PMID:29599806

WenTong HuoXue Cream Can Inhibit the Reduction of the Pain-Related Molecule PLC-β3 in the Dorsal Root Ganglion of a Rat Model of Diabetic Peripheral Neuropathy.

PubMed

Feng, Chengcheng; Xu, Lijuan; Guo, Shiyun; Chen, Qian; Shen, Yuguo; Zang, Deng; Ma, Li

2018-01-01

WenTong HuoXue Cream (WTHX-Cream) has been shown to effectively alleviate clinical symptoms of diabetic peripheral neuropathy (DPN). This study investigated the gene and protein expression of the pain-related molecule PLC- β 3 in the dorsal root ganglion (DRG) of DPN rats. 88 specific pathogen-free male Wistar rats were randomly divided into placebo (10 rats) and DPN model (78 rats) groups, and the 78 model rats were used to establish the DPN model by intraperitoneal injection of streptozotocin and were then fed a high-fat diet for 8 weeks. These rats were randomly divided into the model group, the high-, medium-, and low-dose WTHX-Cream + metformin groups, the metformin group, the capsaicin cream group, and the capsaicin cream + metformin group. After 4 weeks of continuous drug administration, the blood glucose, body weight, behavioral indexes, and sciatic nerve conduction velocity were measured. The pathological structure of the DRG and the sciatic nerve were observed. PLC- β 3 mRNA and protein levels in the DRG of rats were measured. Compared with the model group, the high-dose WTHX-Cream group showed increased sciatic nerve conduction velocity, improved sciatic nerve morphological changes, and increased expression of PLC- β 3 mRNA and protein in the DRG. This study showed that WTHX-Cream improves hyperalgesia symptoms of DPN by inhibiting the reduction of PLC- β 3 mRNA and protein expression in the diabetic DRG of DPN rats.

Modeling of workflow-engaged networks on radiology transfers across a metro network.

PubMed

Camorlinga, Sergio; Schofield, Bruce

2006-04-01

Radiology metro networks bear the challenging proposition of interconnecting several hospitals in a region to provide a comprehensive diagnostic imaging service. Consequences of a poorly designed and implemented metro network could cause delays or no access at all when health care providers try to retrieve medical cases across the network. This could translate into limited diagnostic services to patients, resulting in negative impacts to the patients' medical treatment. A workflow-engaged network (WEN) is a new network paradigm. A WEN appreciates radiology workflows and priorities in using the network. A WEN greatly improves the network performance by guaranteeing that critical image transfers experience minimal delay. It adjusts network settings to ensure the application's requirements are met. This means that high-priority image transfers will have guaranteed and known delay times, whereas lower-priority traffic will have increased delays. This paper introduces a modeling to understand the benefits that WEN brings to a radiology metro network. The modeling uses actual data patterns and flows found in a hospital metro region. The workflows considered are based on the Integrating the Healthcare Enterprise profiles. This modeling has been applied to metropolitan workflows of a health region. The modeling helps identify the kind of metro network that supports data patterns and flows in a metro area. The results of the modeling show that a 155-Mb/s metropolitan area network (MAN) with WEN operates virtually equal to a normal 622-Mb/s MAN without WEN, with potential cost savings for leased line services measured in the millions of dollars per year.

Spectroscopic classification of SN 2018kv as a type Ia supernova

NASA Astrophysics Data System (ADS)

Zhang, Jujia; Lu, Kaixing; Wang, Xiaofeng; Xu, Zhijian; Li, Wenxiong; Zhang, Tianmeng; Tan, Hanjie; Li, Zhitong; Song, Hao; University, Jun Mo (Tsinghua

2018-01-01

We obtained an optical spectrum (range 350-900 nm) of SN 2018kv, discovered by the Tsinghua-NAOC Transient Survey, on UT 2018 Jan. 26.9 with the Li-Jiang 2.4 m telescope (LJT+YFOSC) at Li-Jiang Observatory of Yunnan Observatories.

Spectroscopic Classification of SN 2017ixe as a Type Ia Supernova

NASA Astrophysics Data System (ADS)

Zhang, Jujia; Yu, Xiaoguang; Wang, Xiaofeng

2017-12-01

We obtained an optical spectrum (range 340-900 nm) of SN 2017ixe (PSP17G), discovered by XOSS, on UT Dec. 15.7 2017 with the Li-Jiang 2.4 m telescope (LJT + YFOSC) at Li-Jiang Observatory of Yunnan Observatories (YNAO).

Spectroscopic classification of SN 2018iq as a Type Ia Supernova

NASA Astrophysics Data System (ADS)

Zhang, Jujia; Lu, Kaixing; Wang, Xiaofeng

2018-01-01

We obtained an optical spectrum (range 350-900 nm) of SN 2018iq (=AT2017jzx), discovered by Koichi Itagaki, on UT 2018 Jan. 20.7 with the Li-Jiang 2.4 m telescope (LJT+YFOSC) at Li-Jiang Observatory of Yunnan Observatories.

Entanglement Rate for Gaussian Continuous Variable Beams

DTIC Science & Technology

2016-08-24

beams can then be decomposed into a sum, because of the additivity of the logarithmic negativity: å w= w> E T E . 4N N 0 ( ) [ ] ( ) Wenote that wEN...2 . 5E T N N 0 ( ) [ ] ( ) This shows that wEN [ ] itselfmay be interpreted as the entanglement rate per frequency interval. It is possible to give an...spectral density of entanglement, since it is closely related to wEN [ ]. Setting º á ñ +w w+ n A A1, 1, 1 2 ˆ ˆ† , º á ñ +w w- - - n A A2, 2, 1 2 ˆ ˆ

Spectroscopic Classification of SN 2017ixg as a young Type Ia Supernova with detached HVF of Si II 6355

NASA Astrophysics Data System (ADS)

Zhang, Jujia; Yu, Xiaoguang; Wang, Xiaofeng

2017-12-01

We obtained an optical spectrum (range 340-900 nm) of SN 2017ixg (ATLAS17nrq), discovered by ATLAS and TNTS, on UT Dec. 15.6 2017 with the Li-Jiang 2.4 m telescope (LJT + YFOSC) at Li-Jiang Observatory of Yunnan Observatories (YNAO).

A secure and efficient chaotic map-based authenticated key agreement scheme for telecare medicine information systems.

PubMed

Mishra, Dheerendra; Srinivas, Jangirala; Mukhopadhyay, Sourav

2014-10-01

Advancement in network technology provides new ways to utilize telecare medicine information systems (TMIS) for patient care. Although TMIS usually faces various attacks as the services are provided over the public network. Recently, Jiang et al. proposed a chaotic map-based remote user authentication scheme for TMIS. Their scheme has the merits of low cost and session key agreement using Chaos theory. It enhances the security of the system by resisting various attacks. In this paper, we analyze the security of Jiang et al.'s scheme and demonstrate that their scheme is vulnerable to denial of service attack. Moreover, we demonstrate flaws in password change phase of their scheme. Further, our aim is to propose a new chaos map-based anonymous user authentication scheme for TMIS to overcome the weaknesses of Jiang et al.'s scheme, while also retaining the original merits of their scheme. We also show that our scheme is secure against various known attacks including the attacks found in Jiang et al.'s scheme. The proposed scheme is comparable in terms of the communication and computational overheads with Jiang et al.'s scheme and other related existing schemes. Moreover, we demonstrate the validity of the proposed scheme through the BAN (Burrows, Abadi, and Needham) logic.

[Meanings and conceptualizations of nursing: the point of view of students from the nursing degree program at the Universidad Nacional de Lanús, 2008-2010].

PubMed

Arakaki, Jorge

2013-08-01

This work looks into the meanings of nursing from the point of view of the students in an undergraduate nursing degree program. The research took place at the Universidad Nacional de Lanús using semistructured interviews - eleven individual and seven group interviews - carried out between 2008 and 2010. A content analysis was then undertaken and the most relevant meanings in relation to four themes were selected: reasons for studying nursing, what nursing is, nursing as a profession, and working in nursing. Multiple and diverse ways of defining nursing were uncovered. Utilizing some conceptual developments from the sociology of the professions, the meanings were organized into four conceptualizations that represent ways of understanding nursing: as a vocation, as a profession, with a utilitarian perspective and with a community perspective. The conclusions reached indicate the need to broaden the debate regarding the types of nurses that are being trained.

Dark nights reverse metabolic disruption caused by dim light at night.

PubMed

Fonken, L K; Weil, Z M; Nelson, R J

2013-06-01

The increasing prevalence of obesity and related metabolic disorders coincides with increasing exposure to light at night. Previous studies report that mice exposed to dim light at night (dLAN) develop symptoms of metabolic syndrome. This study investigated whether mice returned to dark nights after dLAN exposure recover metabolic function. Male Swiss-Webster mice were assigned to either: standard light-dark (LD) conditions for 8 weeks (LD/LD), dLAN for 8 weeks (dLAN/dLAN), LD for 4 weeks followed by 4 weeks of dLAN (LD/dLAN), and dLAN for 4 weeks followed by 4 weeks of LD (dLAN/LD). After 4 weeks in their respective lighting conditions both groups initially placed in dLAN increased body mass gain compared to LD mice. Half of the dLAN mice (dLAN/LD) were then transferred to LD and vice versa (LD/dLAN). Following the transfer dLAN/dLAN and LD/dLAN mice gained more weight than LD/LD and dLAN/LD mice. At the conclusion of the study dLAN/LD mice did not differ from LD/LD mice with respect to weight gain and had lower fat pad mass compared to dLAN/dLAN mice. Compared to all other groups dLAN/dLAN mice decreased glucose tolerance as indicated by an intraperitoneal glucose tolerance test at week 7, indicating that dLAN/LD mice recovered glucose metabolism. dLAN/dLAN mice also increased MAC1 mRNA expression in peripheral fat as compared to both LD/LD and dLAN/LD mice, suggesting peripheral inflammation is induced by dLAN, but not sustained after return to LD. These results suggest that re-exposure to dark nights ameliorates metabolic disruption caused by dLAN exposure. Copyright © 2013 The Obesity Society.

Scientific Evidence for Hydrostatic Shock

DTIC Science & Technology

2010-01-01

Z, Jiang J, Bian, X, Savic J, Ultrastructural and Functional Characteristics of Blast Injury-Induced Neurotrauma, The Journal of Trauma, 50:695...706, 2001. 21. Cernak I, Wang, Z, Jiang J, Bian, X, Savic J, Cognitive deficits following blast injury- induced neurotrauma, Brain Injury, 15(7

Blast-Induced Moderate Neurotrauma (BINT) Elicits Early Complement Activation and Tumor Necrosis Factor Alpha (TNFalpha) Release in a Rat Brain

DTIC Science & Technology

2012-04-25

Jiang J, Bian X, Savic J. Cognitive deficits following blast injury- induced neurotrauma: possible involvement of nitric oxide. Brain Inj 2001;15: 593...612. [8] Cernak I, Wang Z, Jiang J, Bian X, Savic J. Ultrastructural and functional character- istics of blast injury-induced neurotrauma. J Trauma

Protective effects of a traditional Chinese herbal formula Jiang-Xian HuGan on Concanavalin A-induced mouse hepatitis via NF-κB and Nrf2 signaling pathways.

PubMed

Tang, Huan-Huan; Li, Hai-Long; Li, Yue-Xuan; You, Yan; Guan, Yun-Yun; Zhang, Su-Lin; Liu, Li-Xin; Bao, Wei-Lian; Zhou, Yong; Shen, Xiao-Yan

2018-05-10

Jiang-Xian HuGan (JXHG) formulated by five natural products including Freshwater clam (Corbicula fluminea), Curcuma longa L., Ligustrum lucidum, Eclipta prostrata (L.) L. and Paeonia lactiflora Pall., has exhibited a great hepatoprotective effect. We investigated the effect of JXHG on concanavalin A (ConA)-induced acute live injury in mice, and to elucidate its underlying molecular mechanisms. Jiangkanling Capsule (900 mg/kg), low-dose JXHG (LJXHG, 700 mg/kg), high-dose JXHG (HJXHG, 1400 mg/kg) were administered to mice by oral gavage daily for 20 days prior to a single intravenous injection of ConA (20 mg/kg). Liver injury was evaluated by measuring the serum levels of enzymes and cytokines as well as liver histological analysis. We also measured the hepatic expression of cytokines at mRNA levels and the proteins related to NF-κB and Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) signaling pathways. Our results showed that JXHG pretreatment significantly alleviated ConA-induced live injury as evidenced by decreased serum levels of glutamic-pyruvic transaminase (ALT) and glutamic oxalacetic transaminase (AST), and reduced hepatocyte apoptosis and mortality. Furthermore, JXHG was able to significantly reduce the serum levels of proinflammatory cytokines, down-regulate the mRNA expression of interleukin-6 (IL-6) and interferon-γ (IFN-γ), and up-regulate IL-10 as well as superoxide-dimutase-1 (SOD1), glutathione reductase (GSR) and Glutathione peroxidase 2 (GPX2) mRNA in the liver tissues after Con A injection. In addition, JXHG pretreatment dramatically suppressed the phosphorylation of NF-κB p65 (p65), increased Nrf2 expression, and decreased the expression ratio of cleaved caspase-3/caspase-3 in liver tissues. These results suggest that JXHG protects against ConA-induced acute live injury through inhibiting NF-κB mediated inflammatory pathway and promoting Nrf2 mediated anti-oxidative stress signaling pathway. Copyright © 2018 Elsevier B.V. All

Chinese Vocational Education: Borrowing and Reforming

ERIC Educational Resources Information Center

Wang, Lei; Jiang, Dayuan

2013-01-01

In July 2010 in Beijing, Lei Wang interviewed Professor Dayuan Jiang, Research Fellow at the Ministry of Education's Central Institute for Vocational and Technical Education about how China has drawn from foreign vocational education models and China's own innovation process. Jiang pointed out that Germany's educational philosophy and talent…

Teaching "Red Scarf Girl". A Facing History and Ourselves Study Guide

ERIC Educational Resources Information Center

Kanner, Elisabeth Fieldstone

2009-01-01

Ji-li Jiang's extraordinary memoir "Red Scarf Girl" transports readers to a tumultuous time in Chinese history--the first two years of the Great Proletarian Cultural Revolution. Caught between conflicting forces--joining the Revolution's call for rebellion, protecting her family, and fitting in with her peers--Jiang describes how her…

Cerebrovascular Injury Caused by a High Strain Rate Insult in the Thorax

DTIC Science & Technology

2012-01-17

AD693105 3. Cernak I. Penetrating and blast injury. Restor Neurol Neurosci 2005; 23 139-143 4. Cernak I, Wang Z, Jiang J, Bian X, Savic J. Ultrastructural...insult in the thorax 4 5. Cernak I, Wang Z, Jiang J, Bian X, Savic J. Cognitive deficits following blast-induced neurotrauma: possible

Management Requirements of the 3COM Ethernet Local Area Network

DTIC Science & Technology

1988-09-01

Management Information System . With the introduction of new technology comes the requirement to administer the network. This paper describes LAN services available on the network, management philosophies for the LAN services, and areas of LAN administration considered important to the successful operation and maintenance of a LAN. LAN administration problems identified by users are also addressed. Keywords included; Local area network (LAN); Lan management; Lan administration; 3COM ETHERNET LAN.

Spectroscopic classification of PTSS-18fdb (AT 2018cni) as a peculiar type Ia supernova before maximum

NASA Astrophysics Data System (ADS)

Zhang, Jujia; Tan, Hanjie; Li, Wenxiong; Li, Bin; Li, Zhitong; Wang, Xiaofeng; Xu, Zhijian; Zhao, Haibin; Wang, Lifan

2018-06-01

We obtained an optical spectrum (range 350-890 nm) of PTSS-18fdb (AT 2018cni), discovered by the PMO-Tsinghua Supernova Survey (PTSS, http://www.cneost.org/ptss/), on UT 2018 June 17.7 with the Li-Jiang 2.4 m telescope (LJT+YFOSC) at Li-Jiang Observatory of Yunnan Observatories.

Spectroscopic classification of PTSS-18ecg (SN 2018bhb) as a type Ia supernova around maximum

NASA Astrophysics Data System (ADS)

Zhang, Jujia; Ding, Xu; Wang, Xiaofeng; Li, Wenxiong; Li, Bin; Xu, Zhijian; Tan, Hanjie; Zhao, Haibin; Wang, Lifan; Li, Zhitong

2018-05-01

We obtained an optical spectrum (range 350-890 nm) of PTSS-18ecg (SN 2018bhb), discovered by the PMO-Tsinghua Supernova Survey (PTSS, http://www.cneost.org/ptss/), on UT 2018 May 10.7 with the Li-Jiang 2.4 m telescope (LJT+YFOSC) at Li-Jiang Observatory of Yunnan Observatories.

How L2 Words Are Stored: The Episodic L2 Hypothesis

ERIC Educational Resources Information Center

Witzel, Naoko Ouchi; Forster, Kenneth I.

2012-01-01

This article reports findings from 3 experiments examining whether 2nd language (L2) words are represented in episodic memory, as originally proposed by Jiang and Forster (2001). Experiment 1 was a direct replication of Jiang and Forster, testing highly proficient Chinese-English bilinguals. Masked translation priming was obtained in an episodic…

BMP7 Induces Dormancy of Prostatic Tumor Stem Cell in Bone

DTIC Science & Technology

2013-07-01

Watabe, Shigeru Hirota, Sudha K. Pai, Wen Liu, Koji Fukuda, Christopher Chambers, Andrew Wilber and Kounosuke Watabe “Bone Figure 7. Expression of BMP7...Hiroshi Okuda,1 Fei Xing,1 Puspa R. Pandey,1 Misako Watabe,1 Shigeru Hirota,2 Sudha K. Pai,1 Wen Liu,1 Koji Fukuda,1 Christopher Chambers,1 Andrew

Gaining perspective on the water-energy nexus at the community scale.

PubMed

Perrone, Debra; Murphy, Jennifer; Hornberger, George M

2011-05-15

Water and energy resources are interrelated but their influence on each other is rarely considered. To quantify the water and energy portfolios associated with a community's water-energy nexus (WEN) and the influence of geographic location on resources, we present the WEN tool. The WEN tool quantifies a community's transport (consumed for or lost before delivery) and nexus (energy for water and water for energy) resources so communities can assess their resource flows. In addition, to provide insight into the full range of impacts of water and energy resource acquisition and to frame the influence of geography on resources, we coin the term "urban resource islands". The concept of urban resource islands provides a framework for considering the implication of geography on a community's water and energy resource acquisition and use. The WEN tool and the concept of resource islands can promote communities to think about their hidden resources and integrate such concepts into their sustainability trade-off analyses and policy decisions. In this paper, we use Tucson, Arizona, United States as a case study.

[Textual research of Liu Wan-su's works on consumptive thirst].

PubMed

Yang, Shi-Zhe; Zhang, Xian-Zhe

2007-07-01

Liu Wan-su's San xiao lun (On Three Consumptions) was the earliest extant monograph dealing with the consumption thirst in traditional Chinese medicine (TCM). The other book, with the namesake of Liu Wan-su, Su wen bing ji qi yi bao ming ji (Collection for Preserving Life of Pathogenesis in Plain Questions), also included a section of consumption thirst. However, through comparison, the descriptions in both books were quite different and it seemed unlikely that it were written by the same author. Based on textural research of bibliography, it's hard to say if this is a true one. Further, comparison of the book with the texts of consumption thirst in Huang di su wen xuan ming lun fang (Elucidated Prescriptions and Expositions of Huangdi's Plain Questions), an authentic book of Liu, a consistency was found between San xiao lun and Huang di su wen xuan ming lun fang. It is very unlikely that Su wen bing ji qi yi bao ming ji was written by Liu because of its obvious different writing style.

Vatuximab(Trademark): Optimizing Therapeutic Strategies for Prostate Cancer Based on Dynamic MR Tumor Oximetry

DTIC Science & Technology

2010-01-01

159: 621-631, 2003. 37. Bourke, V. A., Zhao, D., Gilio , J., Chang, C.-H., Jiang, L., Hahn, E. W., and Mason, R. P. Correlation of Radiation...Res. 1998; 150: 549–556. 10. Bourke VA, Zhao D, Gilio J, Chang C-H, Jiang L, Hahn EW, Mason RP. Correlation of radiation response with tumor oxygen

Efficacy and Safety of LixiLan, a Titratable Fixed-Ratio Combination of Insulin Glargine Plus Lixisenatide in Type 2 Diabetes Inadequately Controlled on Basal Insulin and Metformin: The LixiLan-L Randomized Trial.

PubMed

Aroda, Vanita R; Rosenstock, Julio; Wysham, Carol; Unger, Jeffrey; Bellido, Diego; González-Gálvez, Guillermo; Takami, Akane; Guo, Hailing; Niemoeller, Elisabeth; Souhami, Elisabeth; Bergenstal, Richard M

2016-11-01

This study was conducted to demonstrate the efficacy and safety of LixiLan (iGlarLixi), a novel, titratable, fixed-ratio combination of insulin glargine (iGlar) (100 units) and lixisenatide, compared with iGlar in patients with type 2 diabetes inadequately controlled on basal insulin with or without up to two oral glucose-lowering agents. After a 6-week run-in when iGlar was introduced and/or further titrated, and oral antidiabetic drugs other than metformin were stopped, 736 basal insulin-treated patients (mean diabetes duration 12 years, BMI 31 kg/m 2 ) were randomized 1:1 to open-label, once-daily iGlarLixi or iGlar, both titrated to fasting plasma glucose <100 mg/dL (<5.6 mmol/L) up to a maximum dose of 60 units/day. The primary outcome was change in HbA 1c levels at 30 weeks. HbA 1c decreased from 8.5% (69 mmol/mol) to 8.1% (65 mmol/mol) during the run-in period. After randomization, iGlarLixi showed greater reductions in HbA 1c from baseline compared with iGlar (-1.1% vs. -0.6%, P < 0.0001), reaching a mean final HbA 1c of 6.9% (52 mmol/mol) compared with 7.5% (58 mmol/mol) for iGlar. HbA 1c <7.0% (53 mmol/mol) was achieved in 55% of iGlarLixi patients compared with 30% on iGlar. Mean body weight decreased by 0.7 kg with iGlarLixi and increased by 0.7 kg with iGlar (1.4 kg difference, P < 0.0001). Documented symptomatic hypoglycemia (≤70 mg/dL) was comparable between groups. Mild gastrointestinal adverse effects were very low but more frequent with iGlarLixi. Compared with iGlar, a substantially higher proportion of iGlarLixi-treated patients achieved glycemic targets with a beneficial effect on body weight, no additional risk of hypoglycemia, and low levels of gastrointestinal adverse effects in inadequately controlled, basal insulin-treated, long-standing type 2 diabetes. © 2016 by the American Diabetes Association.

Women with endometriosis improved their peripheral antioxidant markers after the application of a high antioxidant diet

PubMed Central

Mier-Cabrera, Jennifer; Aburto-Soto, Tania; Burrola-Méndez, Soraya; Jiménez-Zamudio, Luis; Tolentino, Mari C; Casanueva, Esther; Hernández-Guerrero, César

2009-01-01

Background Oxidative stress has been identified in the peritoneal fluid and peripheral blood of women with endometriosis. However, there is little information on the antioxidant intake for this group of women. The objectives of this work were 1) to compare the antioxidant intake among women with and without endometriosis and 2) to design and apply a high antioxidant diet to evaluate its capacity to reduce oxidative stress markers and improve antioxidant markers in the peripheral blood of women with endometriosis. Methods Women with (WEN, n = 83) and without endometriosis (WWE, n = 80) were interviewed using a Food Frequency Questionnaire to compare their antioxidant intake (of vitamins and minerals). Then, the WEN participated in the application of a control (n = 35) and high antioxidant diet (n = 37) for four months. The high antioxidant diet (HAD) guaranteed the intake of 150% of the suggested daily intake of vitamin A (1050 μg retinol equivalents), 660% of the recommended daily intake (RDI) of vitamin C (500 mg) and 133% of the RDI of vitamin E (20 mg). Oxidative stress and antioxidant markers (vitamins and antioxidant enzymatic activity) were determined in plasma every month. Results Comparison of antioxidant intake between WWE and WEN showed a lower intake of vitamins A, C, E, zinc, and copper by WEN (p < 0.05, Mann Whitney Rank test). The selenium intake was not statistically different between groups. During the study, the comparison of the 24-hour recalls between groups showed a higher intake of the three vitamins in the HAD group. An increase in the vitamin concentrations (serum retinol, alpha-tocopherol, leukocyte and plasma ascorbate) and antioxidant enzyme activity (superoxide dismutase and glutathione peroxidase) as well as a decrease in oxidative stress markers (malondialdehyde and lipid hydroperoxides) were observed in the HAD group after two months of intervention. These phenomena were not observed in the control group. Conclusion WEN had a lower

Improving the Cost Efficiency and Readiness of MC-130 Aircrew Training: A Case Study

DTIC Science & Technology

2015-01-01

51 Jiang, Changbing, "A reliable solver of Euclidean traveling salesman problems with Microsoft excel add-in tools for small-size systems...DisplayPage.aspx?DocType=Reference&ItemId=+++1 343364&Pubabbrev=JAWA 124 Jiang, Changbing, "A Reliable Solver of Euclidean Traveling Salesman Problems with...49 Figure 4.5 Training Resources Locations Traveling Salesperson Problem In order to participate in training, aircrews must fly to the

Design and Implementation of Secure Area Expansion Scheme for Public Wireless LAN Services

NASA Astrophysics Data System (ADS)

Watanabe, Ryu; Tanaka, Toshiaki

Recently, wireless LAN (WLAN) technology has become a major wireless communication method. The communication bandwidth is increasing and speeds have attained rates exceeding 100 Mbps. Therefore, WLAN technology is regarded as one of the promising communication methods for future networks. In addition, public WLAN connection services can be used in many locations. However, the number of the access points (AP) is insufficient for seamless communication and it cannot be said that users can use the service ubiquitously. An ad-hoc network style connection can be used to expand the coverage area of a public WLAN service. By relaying the user messages among the user nodes, a node can obtain an Internet connection via an AP, even though the node is located outside the AP's direct wireless connection area. Such a coverage area extending technology has many advantages thanks to the feature that no additional infrastructure is required. Therefore, there is a strong demand for this technology as it allows the cost-effective construction of future networks. When a secure ad-hoc routing protocol is used for message exchange in the WLAN service, the message routes are protected from malicious behavior such as route forging and can be maintained appropriately. To do this, however, a new node that wants to join the WLAN service has to obtain information such as the public key certificate and IP address in order to start secure ad-hoc routing. In other words, an initial setup is required for every network node to join the WLAN service properly. Ordinarily, such information should be assigned from the AP. However, new nodes cannot always contact an AP directly. Therefore, there are problems about information delivery in the initial setup of a network node. These problems originate in the multi hop connection based on the ad-hoc routing protocols. In order to realize an expanded area WLAN service, in this paper, the authors propose a secure public key certificate and address provision

Molecular structure, FT IR, NMR, UV, NBO and HOMO-LUMO of 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile by DFT/B3LYP and PBEPBE methods with LanL2DZ and 6-311++G(d,2p) basis sets.

PubMed

Khajehzadeh, Mostafa; Moghadam, Majid

2017-06-05

Structural and molecular properties of antidepressants 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile were examined using quantum mechanics of Density Functional Theory (DFT)/B3LYP and PBEPBE methods with 6-311++G(d,2p) and LanL2DZ basis sets to study the therapeutic properties of the drug. For this, the structure of desired material was optimized by the computer calculation method and with the use of powerful Gaussian 09 software. Then the lowest energy value and the bond length, bond angle and dihedral angle between its constituent atoms in the crystal structure of the desired material were measured from the optimized values. Then the amount of positive and negative charges, polarizability and dipole moment of its atoms using Mulliken charge and Natural atomic charges, DFT/B3LYP and PBEPBE methods with 6-311++G(d,2p) and LanL2DZ basis sets were determined and the results were compared with each other for individual atoms and by mentioned methods. Also the type of stretching vibrations and bending vibrations between the constituent atoms of the molecule were specified using mentioned computational methods and FT IR vibrational spectra. The experimental spectrum of this material was taken to determine the functional groups and the computational and experimental values were compared to each other and Nuclear Magnetic Resonance (NMR) was used to specify the isomer shift between the carbons and protons in the presence of polar and nonpolar solvents. Also Natural Bond Orbital (NBO) was used to determine the type of electron transfers in σ→σ∗ and π→π∗ and LP(1)→σ∗ and LP(2)→σ∗ and the amount of hardness and softness in molecule was determined using the difference between ionization energy and electron affinity energy in constituent atoms of that molecule in the highest occupied molecular orbital (HOMO) and lowest unoccupied molecular orbital (LUMO) and in the presence of solvents H 2 O, CH 3 CN and C 6 H 12

Molecular structure, FT IR, NMR, UV, NBO and HOMO-LUMO of 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile by DFT/B3LYP and PBEPBE methods with LanL2DZ and 6-311 ++G(d,2p) basis sets

NASA Astrophysics Data System (ADS)

Khajehzadeh, Mostafa; Moghadam, Majid

2017-06-01

Structural and molecular properties of antidepressants 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile were examined using quantum mechanics of Density Functional Theory (DFT)/B3LYP and PBEPBE methods with 6-311 ++ G(d,2p) and LanL2DZ basis sets to study the therapeutic properties of the drug. For this, the structure of desired material was optimized by the computer calculation method and with the use of powerful Gaussian 09 software. Then the lowest energy value and the bond length, bond angle and dihedral angle between its constituent atoms in the crystal structure of the desired material were measured from the optimized values. Then the amount of positive and negative charges, polarizability and dipole moment of its atoms using Mulliken charge and Natural atomic charges, DFT/B3LYP and PBEPBE methods with 6-311 ++ G(d,2p) and LanL2DZ basis sets were determined and the results were compared with each other for individual atoms and by mentioned methods. Also the type of stretching vibrations and bending vibrations between the constituent atoms of the molecule were specified using mentioned computational methods and FT IR vibrational spectra. The experimental spectrum of this material was taken to determine the functional groups and the computational and experimental values were compared to each other and Nuclear Magnetic Resonance (NMR) was used to specify the isomer shift between the carbons and protons in the presence of polar and nonpolar solvents. Also Natural Bond Orbital (NBO) was used to determine the type of electron transfers in σ → σ ∗ and π → π ∗ and LP(1) → σ ∗ and LP(2) → σ ∗ and the amount of hardness and softness in molecule was determined using the difference between ionization energy and electron affinity energy in constituent atoms of that molecule in the highest occupied molecular orbital (HOMO) and lowest unoccupied molecular orbital (LUMO) and in the presence of solvents H2O, CH3CN

Methanohalophilus zhilinae sp. nov., an alkaliphilic, halophilic, methylotrophic methanogen

NASA Technical Reports Server (NTRS)

Mathrani, I. M.; Boone, D. R.; Mah, R. A.; Fox, G. E.; Lau, P. P.

1988-01-01

Methanohalophilus zhilinae, a new alkaliphilic, halophilic, methylotrophic species of methanogenic bacteria, is described. Strain WeN5T (T = type strain) from Bosa Lake of the Wadi el Natrun in Egypt was designated the type strain and was further characterized. This strain was nonmotile, able to catabolize dimethylsulfide, and able to grow in medium with a methyl group-containing substrate (such as methanol or trimethylamine) as the sole organic compound added. Sulfide (21 mM) inhibited cultures growing on trimethylamine. The antibiotic susceptibility pattern of strain WeN5T was typical of the pattern for archaeobacteria, and the guanine-plus-cytosine content of the deoxyribonucleic acid was 38 mol%. Characterization of the 16S ribosomal ribonucleic acid sequence indicated that strain WeN5T is phylogenetically distinct from members of previously described genera other than Methanohalophilus and supported the partition of halophilic methanogens into their own genus.

Leptotrombidium (Acari: Trombiculidae) of the World.

PubMed

Stekolnikov, Alexandr A

2013-01-01

The chigger mite genus Leptotrombidium Nagayo, Miyagawa, Mitamura and Imamura, 1916 is reviewed using literature data. For 340 larval species brief diagnoses, synonymy, data on type hosts and type localities are provided. The genus is divided into species-groups based on morphological evidence enabling easier establishment of group-membership of un-known specimens in the future. Some species groups are supported by a hierarchical cluster analysis with multiscale boot-strap resampling applied to a matrix including 335 species and geographic morphotypes and 19 standard quantitative characters. Six new species from mammalian hosts are described: L. aenigmami sp. nov., L. abramovi sp. nov., L. tikhon-ovi sp. nov., L. bochkovi sp. nov., L. laoense sp. nov., and L. megaloti sp. nov. from Laos. Seven names created by Ver-cammen-Grandjean and Langston (1976) for infrasubspecific entities are applied to species with the same descriptions: Leptotrombidium tenompaki sp. nov., L. kinabalui sp. nov., L. megabodense sp. nov., L. minului sp. nov., L. ului sp. nov., L. megalangati sp. nov., and L. saigoni sp. nov. A new replacement name is proposed: L. ushi nom. nov. pro L. hsui Wu, Yang and Li, 1999 (praeocc. Yu, Yang and Gong, 1986). Nineteen new synonyms and 7 new combinations are proposed: Leptotrombidium (= Hsuella Wang, Li and Shi, 1989, syn. nov.; = Leptotrombidium (Monosigmum) Wen, 2001, syn. nov.), L. deliense (Walch, 1922) (= L. deliense sinense Wen and Chen, 1984, syn. nov.; = L. deliense microsetosa Zhao, Tang and Mo, 1986, syn. nov.), L. sialkotense Vercammen-Grandjean and Langston, 1976 (= L. jishoum Wen, Li, Zhang and Liao, 1988, syn. nov.), L. imphalum Vercammen-Grandjean and Langston, 1976 (= L. imphalum sabahense Vercam-men-Grandjean and Langston, 1976, syn. nov.; = L. chiangraiensis Tanskul and Linthicum, 1997, syn. nov.), L. wenense Wu, Wen, Yang and Wu, 1982 (= L. kaohuense Li, Wang and Chen, 1997, syn. nov.), L. longimedian Brown, 1992 (= L. mindanensis Brown

Water Activated Doping and Transport in Multilayered Germanane Crystals

DTIC Science & Technology

2015-09-21

Justin Young, Basant Chitara , Nicholas Cultrara , Maxx Q Arguilla , Shishi Jiang, Fan Fan , Ezekiel Johnston-Halperin, Joshua E Goldberger 611102 c...Crystals Justin R Young1, Basant Chitara2, Nicholas D Cultrara2, Maxx Q Arguilla2, Shishi Jiang2, Fan Fan2 Ezekiel Johnston-Halperin1, Joshua E...Optoelectronics ACS Nano 7 5660-5 [9] Zhang Y, Tan Y-W, Stormer H L and Kim P 2005 Experimental observation of the quantum Hall effect and Berry’s phase in

Evaluation of wireless Local Area Networks

NASA Astrophysics Data System (ADS)

McBee, Charles L.

1993-09-01

This thesis is an in-depth evaluation of the current wireless Local Area Network (LAN) technologies. Wireless LAN's consist of three technologies: they are infrared light, microwave, and spread spectrum. When the first wireless LAN's were introduced, they were unfavorably labeled slow, expensive, and unreliable. The wireless LAN's of today are competitively priced, more secure, easier to install, and provide equal to or greater than the data throughput of unshielded twisted pair cable. Wireless LAN's are best suited for organizations that move office staff frequently, buildings that have historical significance, or buildings that have asbestos. Additionally, an organization may realize a cost savings of between $300 to $1,200 each time a node is moved. Current wireless LAN technologies have a positive effect on LAN standards being developed by the Defense Information System Agency (DISA). DoD as a whole is beginning to focus on wireless LAN's and mobile communications. If system managers want to remain successful, they need to stay abreast of this technology.

Local Area Networks.

ERIC Educational Resources Information Center

Nasatir, Marilyn; And Others

1990-01-01

Four papers discuss LANs (local area networks) and library applications: (1) "Institute for Electrical and Electronic Engineers Standards..." (Charles D. Brown); (2) "Facilities Planning for LANs..." (Gail Persky); (3) "Growing up with the Alumni Library: LAN..." (Russell Buchanan); and (4) "Implementing a LAN...at the Health Sciences Library"…

Dual regulation of HMGB1 by combined JNK1/2-ATF2 axis with miR-200 family in nonalcoholic steatohepatitis in mice.

PubMed

Chen, Xin; Ling, Yan; Wei, Yanping; Tang, Jing; Ren, Yibing; Zhang, Baohua; Jiang, Feng; Li, Hengyu; Wang, Ruoyu; Wen, Wen; Lv, Guishuai; Wu, Mengchao; Chen, Lei; Li, Liang; Wang, Hongyang

2018-05-01

In the context of diabetes, obesity, and metabolic syndrome, the inflammatory signaling has critical roles in the pathogenesis of nonalcoholic fatty liver disease (NAFLD), but the underlying mechanisms remain poorly delineated. Herein, early and persistently elevated, proinflammatory cytokine HMGB1 expression was detected in a high-fat diet (HFD)-induced NAFLD model in C57BL/6 mice. The expression and extracellular release of HMGB1 was rapidly and dramatically induced by saturated palmitic acid in vitro. HFD-induced inflammatory response and liver function impairment were both mitigated after the inhibition of endogenous HMGB1 by neutralizing antibody in vivo. The up-regulation of HMGB1 was thought to be modified by dual channels: in the transcriptional level, it was regulated by JNK1/JNK2-ATF2 axis; post-transcriptionally, it was regulated by the microRNA (miR)-200 family, especially miR-429. miR-429 liver conditional knockout mice (miR-429 Δhep ), fed either a normal diet or an HFD, showed severe liver inflammation and dysfunction, accompanied by greater expression of HMGB1. Intriguingly, the up-regulation and release of HMGB1 could in turn self-activate TLR4-JNK1/JNK2-ATF2 signaling, thus forming a positive feedback. Our findings reveal a novel mechanism by which HMGB1 expression was regulated by both the JNK1/2-ATF2 axis and the miR-200 family, which provides a potential new approach for the treatment of NAFLD.-Chen, X., Ling, Y., Wei, Y., Tang, J., Ren, Y., Zhang, B., Jiang, F., Li, H., Wang, R., Wen, W., Lv, G., Wu, M., Chen, L., Li, L., Wang, H. Dual regulation of HMGB1 by combined JNK1/2-ATF2 axis with miR-200 family in nonalcoholic steatohepatitis in mice.

Dim light at night prior to adolescence increases adult anxiety-like behaviors.

PubMed

Cissé, Yasmine M; Peng, Juan; Nelson, Randy J

2016-01-01

Dim light at night (dLAN) disrupts circadian organization and influences adult behavior. We examined early dLAN exposure on adult affective responses. Beginning 3 (juvenile) or 5 weeks (adolescent) of age, mice were maintained in standard light-dark cycles or exposed to nightly dLAN (5 lx) for 5 weeks, then anxiety-like and fear responses were assessed. Hypothalami were collected around the clock to assess core clock genes. Exposure to dLAN at either age increased anxiety-like responses in adults. Clock and Rev-ERB expression were altered by exposure to dLAN. In contrast to adults, dLAN exposure during early life increases anxiety and fear behavior.

Improved Group Signature Scheme Based on Quantum Teleportation

NASA Astrophysics Data System (ADS)

Su, Qi; Li, Wen-Min

2014-04-01

Recently, Wen et al. proposed a group signature scheme based on quantum teleportation (Wen et al. 81(5):055001, 2010). In this paper, we find that it is vulnerable to the inside attack, by which all other legal members of the group can forge the signature utilizing the anti-commutative relationship between the Pauli operation Y and the encryption operation H, and the public board. Then we present an improved scheme where the eavesdropping process after the transmission is involved to increase the security.

Dynamics of Radiation and Atoms in Ultrahigh Intensity Laser Fields

DTIC Science & Technology

2013-12-31

Rob Mitchell, N. Ekanayake, A. Watts, S. White , Rob Sauer, L. Howard, M. Videtto, C. Mancuso, S. Wells, T. Stanev, B. Wen, M. Decamp, B. Walker, Sasi...Chen, Z. Bond, A. Loether, L. E. Howard, Y. Gao, S. LeMar, S. White , A. Watts, B. C. Walker, M. F. DeCamp. Reconstructing longitudinal strain pulses...Ekanayake, A.M. Watts, S.L. White , Rob Sauer, L.E. Howard, M. Videtto, C. Mancuso, S.J. Wells, T. Stanev, B.L. Wen, M.F. Decamp, and B.C. Walker. Ionization

The Role of Tumor Metastases Suppressor Gene, Drg-1, in Breast Cancer

DTIC Science & Technology

2009-03-01

the bone of nude mice. Clin Cancer Res 2003;9:1200–10. 42. Arah IN, Song K, Seth P, Cowan KH, Sinha BK. Role of wild-type p53 in the enhancement of...124. Parr C, G. Watkins , M. Boulton, J. Cai & W. G. Jiang: Placenta growth factor is over-expressed and has prognostic value in human breast cancer...prostate cancer. Int J Cancer 63, 100-105 (1995) 143. Martin T. A, A. Goyal, G. Watkins & W. G. Jiang: Expression of the transcription factors snail

Computational Study of Chalcopyrite Semiconductors and Their Non-Linear Optical Properties

DTIC Science & Technology

2007-09-12

34 Xiaoshu Jiang, M. S. Miao , and Walter R. Lambrecht, Phys. Rev. B 71, 205212 (2005). 4. "Structure and phonons of ZnGeN 2 ," Walter R. Lambrecht, Erik All...dredge, and Kwiseon Kim Phys. Rev. B 72, 155202 (2005) 5. "Theoretical study of the phosphorus vacancy in ZnGeP 2 ," Xiaoshu Jiang, M. S. Miao , and...Rocksalt Phase Transitions," M. S. Miao and Walter R. Lambrecht, Phys. Rev. Lett. 94, 225501 (2005) 1 20070925383 b. Manuscripts submitted to peer

The Association Between Serum Activin A Levels and Hypertension in the Elderly: A Cross-Sectional Analysis From I-Lan Longitudinal Aging Study.

PubMed

Tsai, Yi-Lin; Chang, Chun-Chin; Liu, Li-Kuo; Huang, Po-Hsun; Chen, Liang-Kung; Lin, Shing-Jong

2018-02-09

Hypertension is an important risk factor for cardiovascular disease. Activin A, a member of the transforming growth factor-β cytokine family, has been shown to regulate blood pressure through the renin-angiotensin system. However, the relationship between activin A and blood pressure remains uncertain. The objective of this study was to determine whether serum activin A levels are associated with blood pressure. A total of 470 participants of I-Lan longitudinal Aging Study (ILAS) were eligible for this study. Serum levels of activin A were assessed by enzyme-linked immunosorbent assay. Cross-sectional analyses were performed, including comparisons of demographic characteristics, hypertensive status, and activin A levels. Among the study participants (50% men, mean age, 69 years), 236 (50.2%) were hypertensive and 234 (49.8%) were normotensive. Hypertensive patients had significantly higher serum activin A levels than normotensives (normotensive vs. hypertensive: 507 ± 169 vs. 554 ± 176 pg/ml, mean ± SD, P < 0.001). All subjects were divided into 3 tertiles on the basis of serum activin A levels. Increasing tertiles of activin A were associated with higher systolic blood pressure (SBP), diastolic blood pressure and pulse pressure (PP) (all P < 0.001). After adjusting for all the potential confounding factors, serum activin A concentration was still significantly associated with SBP (P = 0.02) and PP (P = 0.03). Serum activin A level was associated with SBP and PP. Further studies are required to assess their causal relationship and the clinical relevance. © American Journal of Hypertension, Ltd 2017. All rights reserved. For Permissions, please email: journals.permissions@oup.com

Wireless LAN Extension

DTIC Science & Technology

2003-03-01

competing for airspace in the 2.4GHz radio spectrum. Most of these devices are actually common household products like microwaves and cordless phones. Thus...standard for SML, then one important consideration would be to ensure that these household products are not available anywhere near or inside the

A LAN Toolbox.

ERIC Educational Resources Information Center

Eddison, Elizabeth B.

1989-01-01

This bibliographic essay reviews sources that aid in the planning and management aspects of local area networks. Areas covered include system components; basic vocabularies; planning issues, including needs assessment, peripheral sharing alternatives and costs; and management issues, including purchasing, operating systems, installation, network…

A 3.2-GHz fully integrated low-phase noise CMOS VCO with self-biasing current source for the IEEE 802.11a/hiperLAN WLAN standard

NASA Astrophysics Data System (ADS)

Quemada, C.; Adin, I.; Bistue, G.; Berenguer, R.; Mendizabal, J.

2005-06-01

A 3.3V, fully integrated 3.2-GHz voltage-controlled oscillator (VCO) is designed in a 0.18μm CMOS technology for the IEE 802.11a/HiperLAN WLAN standard for the UNII band from 5.15 to 5.35 GHz. The VCO is tunable between 2.85 GHz and 3.31 GHz. NMOS architecture with self-biasing current of the tank source is chosen. A startup circuit has been employed to avoid zero initial current. Current variation is lower than 1% for voltage supply variations of 10%. The use of a self-biasing current source in the tank provides a greater safety in the transconductance value and allows running along more extreme point operation The designed VCO displays a phase noise and output power of -98dBc/Hz (at 100 KHz offset frequency) and 0dBm respectively. This phase noise has been obtained with inductors of 2.2nH and quality factor of 12 at 3.2 GHz, and P-N junction varactors whose quality factor is estimated to exceed 40 at 3.2 GHz. These passive components have been fabricated, measured and modeled previously. The core of the VCO consumes 33mW DC power.

Light at night acutely impairs glucose tolerance in a time-, intensity- and wavelength-dependent manner in rats.

PubMed

Opperhuizen, Anne-Loes; Stenvers, Dirk J; Jansen, Remi D; Foppen, Ewout; Fliers, Eric; Kalsbeek, Andries

2017-07-01

Exposure to light at night (LAN) has increased dramatically in recent decades. Animal studies have shown that chronic dim LAN induced obesity and glucose intolerance. Furthermore, several studies in humans have demonstrated that chronic exposure to artificial LAN may have adverse health effects with an increased risk of metabolic disorders, including type 2 diabetes. It is well-known that acute exposure to LAN affects biological clock function, hormone secretion and the activity of the autonomic nervous system, but data on the effects of LAN on glucose homeostasis are lacking. This study aimed to investigate the acute effects of LAN on glucose metabolism. Male Wistar rats were subjected to i.v. glucose or insulin tolerance tests while exposed to 2 h of LAN in the early or late dark phase. In subsequent experiments, different light intensities and wavelengths were used. LAN exposure early in the dark phase at ZT15 caused increased glucose responses during the first 20 min after glucose infusion (p < 0.001), whereas LAN exposure at the end of the dark phase, at ZT21, caused increased insulin responses during the first 10 min (p < 0.01), indicating that LAN immediately induces glucose intolerance in rats. Subsequent experiments demonstrated that the effect of LAN was both intensity- and wavelength-dependent. White light of 50 and 150 lx induced greater glucose responses than 5 and 20 lx, whereas all intensities other than 5 lx reduced locomotor activity. Green light induced glucose intolerance, but red and blue light did not, suggesting the involvement of a specific retina-brain pathway. Together, these data show that exposure to LAN has acute adverse effects on glucose metabolism in a time-, intensity- and wavelength-dependent manner.

Dim Light at Night Prior to Adolescence Increases Adult Anxiety-like Behaviors

PubMed Central

Cissé, Yasmine M.; Peng, Juan; Nelson, Randy J.

2017-01-01

Dim light at night (dLAN) disrupts circadian organization and influences adult behavior. We examined early dLAN exposure on adult affective responses. Beginning 3 (juvenile) or 5 weeks (adolescent) of age, mice were maintained in standard light-dark cycles or exposed to nightly dLAN (5 lux) for 5 weeks, then anxiety-like and fear responses were assessed. Hypothalami were collected around the clock to assess core clock genes. Exposure to dLAN at either age increased anxiety-like responses in adults. Clock and Rev-ERB expression were altered by exposure to dLAN. In contrast to adults, dLAN exposure during early life increases anxiety and fear behavior. PMID:27592634

Parental Exposure to Dim Light at Night Prior to Mating Alters Offspring Adaptive Immunity.

PubMed

Cissé, Yasmine M; Russart, Kathryn L G; Nelson, Randy J

2017-03-31

Exposure to dim light at night (dLAN) disrupts natural light/dark cycles and impairs endogenous circadian rhythms necessary to maintain optimal biological function, including the endocrine and immune systems. We have previously demonstrated that white dLAN compromises innate and cell mediated immune responses in adult Siberian hamsters (Phodopus sungorus). We hypothesized that dLAN has transgenerational influences on immune function. Adult male and female Siberian hamsters were exposed to either dark nights (DARK) or dLAN (~5 lux) for 9 weeks, then paired in full factorial design, mated, and thereafter housed under dark nights. Offspring were gestated and reared in dark nights, then tested as adults for cell-mediated and humoral immunity. Maternal exposure to dLAN dampened delayed type hypersensitivity (DTH) responses in male offspring. Maternal and paternal exposure to dLAN reduced DTH responses in female offspring. IgG antibodies to a novel antigen were elevated in offspring of dams exposed to dLAN. Paternal exposure to dLAN decreased splenic endocrine receptor expression and global methylation in a parental sex-specific manner. Together, these data suggest that exposure to dLAN has transgenerational effects on endocrine-immune function that may be mediated by global alterations in the epigenetic landscape of immune tissues.

Parental Exposure to Dim Light at Night Prior to Mating Alters Offspring Adaptive Immunity

PubMed Central

Cissé, Yasmine M.; Russart, Kathryn L.G.; Nelson, Randy J.

2017-01-01

Exposure to dim light at night (dLAN) disrupts natural light/dark cycles and impairs endogenous circadian rhythms necessary to maintain optimal biological function, including the endocrine and immune systems. We have previously demonstrated that white dLAN compromises innate and cell mediated immune responses in adult Siberian hamsters (Phodopus sungorus). We hypothesized that dLAN has transgenerational influences on immune function. Adult male and female Siberian hamsters were exposed to either dark nights (DARK) or dLAN (~5 lux) for 9 weeks, then paired in full factorial design, mated, and thereafter housed under dark nights. Offspring were gestated and reared in dark nights, then tested as adults for cell-mediated and humoral immunity. Maternal exposure to dLAN dampened delayed type hypersensitivity (DTH) responses in male offspring. Maternal and paternal exposure to dLAN reduced DTH responses in female offspring. IgG antibodies to a novel antigen were elevated in offspring of dams exposed to dLAN. Paternal exposure to dLAN decreased splenic endocrine receptor expression and global methylation in a parental sex-specific manner. Together, these data suggest that exposure to dLAN has transgenerational effects on endocrine-immune function that may be mediated by global alterations in the epigenetic landscape of immune tissues. PMID:28361901

Ultrafast Optics: Vector Cavity Fiber Lasers - Physics and Technology

DTIC Science & Technology

2016-06-14

with a quasi- vector cavity both numerically and experimentally. It is expected that through the study a deep and comprehensive understanding on the...799-801, Jun. 1997. 31. L. M. Zhao, D. Y. Tang, J. Wu, X. Q. Fu, and S. C. Wen , "Noise-like pulse in a gain-guided soliton fiber laser," Opt...solitons in a ring fiber laser," Optics Communications 281 (22), 5614 (2008). 110. L. M. Zhao, D. Y. Tang, J. Wu, X. Q. Fu, and S. C. Wen , "Noise-like

Ultrafast Optics: Vector Cavity Laser - Physics and Technology

DTIC Science & Technology

2016-06-14

with a quasi- vector cavity both numerically and experimentally. It is expected that through the study a deep and comprehensive understanding on the...799-801, Jun. 1997. 31. L. M. Zhao, D. Y. Tang, J. Wu, X. Q. Fu, and S. C. Wen , "Noise-like pulse in a gain-guided soliton fiber laser," Opt...solitons in a ring fiber laser," Optics Communications 281 (22), 5614 (2008). 110. L. M. Zhao, D. Y. Tang, J. Wu, X. Q. Fu, and S. C. Wen , "Noise-like

Ultrafast Optics - Vector Cavity Lasers: Physics and Technology

DTIC Science & Technology

2016-06-14

with a quasi- vector cavity both numerically and experimentally. It is expected that through the study a deep and comprehensive understanding on the...799-801, Jun. 1997. 31. L. M. Zhao, D. Y. Tang, J. Wu, X. Q. Fu, and S. C. Wen , "Noise-like pulse in a gain-guided soliton fiber laser," Opt...solitons in a ring fiber laser," Optics Communications 281 (22), 5614 (2008). 110. L. M. Zhao, D. Y. Tang, J. Wu, X. Q. Fu, and S. C. Wen , "Noise-like

Spent Nuclear Fuel Transport Reliability Study

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, Jy-An John; Wang, Hong; Jiang, Hao

This conference paper was orignated and shorten from the following publisehd PTS documents: 1. Jy-An Wang, Hao Jiang, and Hong Wang, Dynamic Deformation Simulation of Spent Nuclear Fuel Assembly and CIRFT Deformation Sensor Stability Investigation, ORNL/SPR-2015/662, November 2015. 2. Jy-An Wang, Hong Wang, Mechanical Fatigue Testing of High-Burnup Fuel for Transportation Applications, NUREG/CR-7198, ORNL/TM-2014/214, May 2015. 3. Jy-An Wang, Hong Wang, Hao Jiang, Yong Yan, Bruce Bevard, Spent Nuclear Fuel Vibration Integrity Study 16332, WM2016 Conference, March 6 10, 2016, Phoenix, Arizona.

Dim light at night increases depressive-like responses in male C3H/HeNHsd mice.

PubMed

Fonken, Laura K; Nelson, Randy J

2013-04-15

Daily patterns of light exposure have become increasingly variable since the widespread adoption of electrical lighting during the 20th century. Seasonal fluctuations in light exposure, shift-work, and transmeridian travel are all associated with alterations in mood. These studies implicate fluctuations in environmental lighting in the development of depressive disorders. Here we argue that exposure to light at night (LAN) may be causally linked to depression. Male C3H/HeNHsd mice, which produce nocturnal melatonin, were housed in either a standard light/dark (LD) cycle or exposed to nightly dim (5 lux) LAN (dLAN). After four weeks in lighting conditions mice underwent behavioral testing and hippocampal tissue was collected at the termination of the study for qPCR. Here were report that mice exposed to dLAN increase depressive-like responses in both a sucrose anhedonia and forced swim test. In contrast to findings in diurnal grass rats, dLAN mice perform comparably to mice housed under dark nights in a hippocampus-dependent learning and memory task. TNFα and IL1β gene expression do not differ between groups, demonstrating that changes in these pro-inflammatory cytokines do not mediate dLAN induced depressive-like responses in mice. BDNF expression is reduced in the hippocampus of mice exposed to dLAN. These results indicate that low levels of LAN can alter mood in mice. This study along with previous work implicates LAN as a potential factor contributing to depression. Further understanding of the mechanisms through which LAN contributes to changes in mood is important for characterizing and treating depressive disorders. Copyright © 2013 Elsevier B.V. All rights reserved.

Exponential Stability of Almost Periodic Solutions for Memristor-Based Neural Networks with Distributed Leakage Delays.

PubMed

Xu, Changjin; Li, Peiluan; Pang, Yicheng

2016-12-01

In this letter, we deal with a class of memristor-based neural networks with distributed leakage delays. By applying a new Lyapunov function method, we obtain some sufficient conditions that ensure the existence, uniqueness, and global exponential stability of almost periodic solutions of neural networks. We apply the results of this solution to prove the existence and stability of periodic solutions for this delayed neural network with periodic coefficients. We then provide an example to illustrate the effectiveness of the theoretical results. Our results are completely new and complement the previous studies Chen, Zeng, and Jiang ( 2014 ) and Jiang, Zeng, and Chen ( 2015 ).

A Price To Pay for Relaxed Substrate Specificity: A Comparative Kinetic Analysis of the Class II Lanthipeptide Synthetases ProcM and HalM2

PubMed Central

2015-01-01

Lanthipeptides are a class of ribosomally synthesized and posttranslationally modified peptide natural products (RiPPs) that typically harbor multiple intramolecular thioether linkages. For class II lanthipeptides, these cross-links are installed in a multistep reaction pathway by a single enzyme (LanM). The multifunctional nature of LanMs and the manipulability of their genetically encoded peptide substrates (LanAs) make LanM/LanA systems promising targets for the engineering of new antibacterial compounds. Here, we report the development of a semiquantitative mass spectrometry-based assay for kinetic characterization of LanM-catalyzed reactions. The assay was used to conduct a comparative kinetic analysis of two LanM enzymes (HalM2 and ProcM) that exhibit drastically different substrate selectivity. Numerical simulation of the kinetic data was used to develop models for the multistep HalM2- and ProcM-catalyzed reactions. These models illustrate that HalM2 and ProcM have markedly different catalytic efficiencies for the various reactions they catalyze. HalM2, which is responsible for the biosynthesis of a single compound (the Halβ subunit of the lantibiotic haloduracin), catalyzes reactions with higher catalytic efficiency than ProcM, which modifies 29 different ProcA precursor peptides during prochlorosin biosynthesis. In particular, the rates of thioether ring formation are drastically reduced in ProcM, likely because this enzyme is charged with installing a variety of lanthipeptide ring architectures in its prochlorosin products. Thus, ProcM appears to pay a kinetic price for its relaxed substrate specificity. In addition, our kinetic models suggest that conformational sampling of the LanM/LanA Michaelis complex could play an important role in the kinetics of LanA maturation. PMID:25409537

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lepine, Sebastien; Bergeron, P.; Lanning, Howard H., E-mail: lepine@amnh.org

We present spectroscopic observations confirming the identification of hot white dwarfs among UV-bright sources from the Sandage Two-color Survey of the Galactic Plane and listed in the Lanning (Lan) catalog of such sources. A subsample of 213 UV-bright Lan sources have been identified as candidate white dwarfs based on the detection of a significant proper motion. Spectroscopic observations of 46 candidates with the KPNO 2.1 m telescope confirm 30 sources to be hydrogen white dwarfs with subtypes in the DA1-DA6 range, and with one of the stars (Lan 161) having an unresolved M dwarf as a companion. Five more sourcesmore » are confirmed to be helium white dwarfs, with subtypes from DB3 to DB6. One source (Lan 364) is identified as a DZ 3 white dwarf, with strong lines of calcium. Three more stars are found to have featureless spectra (to within detection limits) and are thus classified as DC white dwarfs. In addition, three sources are found to be hot subdwarfs: Lan 20 and Lan 480 are classified as sdOB, and Lan 432 is classified sdB. The remaining four objects are found to be field F star interlopers. Physical parameters of the DA and DB white dwarfs are derived from model fits.« less

Lanreotide autogel every 6 weeks compared with Lanreotide microparticles every 3 weeks in patients with well differentiated neuroendocrine tumors: a Phase III Study.

PubMed

Bajetta, Emilio; Procopio, Giuseppe; Catena, Laura; Martinetti, Antonia; De Dosso, Sara; Ricci, Sergio; Lecchi, Alberto S; Boscani, Paolo F; Iacobelli, Stefano; Carteni, Giacomo; De Braud, Filippo; Loli, Paola; Tartaglia, Andreas; Bajetta, Roberto; Ferrari, Leonardo

2006-11-15

The noninferiority of a 6-week dosing schedule of lanreotide Autogel (Lan ATG) at a dose of 120 mg compared with a 3-week dosing schedule of lanreotide microparticles (Lan MP) at a dose of 60 mg was investigated in patients with neuroendocrine tumors (NET). Patients who had sporadic, well differentiated NET with a low grade of malignancy were recruited for this open-label, Phase III, multicenter trial. Patients were randomized to receive either 3 deep subcutaneous injections of Lan ATG (120 mg, every 6 weeks) or 6 intramuscular injections of Lan MP (60 mg, every 3 weeks). Tumor markers, tumor size, and symptoms were assessed between baseline and Week 18. Success was classified as a response that ranged from disappearance to an increase <25% in tumor marker, tumor size, or symptom frequency. Sixty patients were randomized, and 46 patients completed the study. Both for tumor markers and for tumor size, Lan ATG was not inferior to Lan MP (55% and 59% of patients responded on tumor markers, respectively; 68% and 66% of patients responded on tumor size, respectively). There were too few symptomatic patients to compare carcinoid symptoms. Both treatments were tolerated well, and no safety concerns were identified. Lan ATG at a dose of 120 mg every 6 weeks was as effective for controlling NET as Lan MP at a dose of 60 mg every 3 weeks.

Listen up, eye movements play a role in verbal memory retrieval.

PubMed

Scholz, Agnes; Mehlhorn, Katja; Krems, Josef F

2016-01-01

People fixate on blank spaces if visual stimuli previously occupied these regions of space. This so-called "looking at nothing" (LAN) phenomenon is said to be a part of information retrieval from internal memory representations, but the exact nature of the relationship between LAN and memory retrieval is unclear. While evidence exists for an influence of LAN on memory retrieval for visuospatial stimuli, evidence for verbal information is mixed. Here, we tested the relationship between LAN behavior and memory retrieval in an episodic retrieval task where verbal information was presented auditorily during encoding. When participants were allowed to gaze freely during subsequent memory retrieval, LAN occurred, and it was stronger for correct than for incorrect responses. When eye movements were manipulated during memory retrieval, retrieval performance was higher when participants fixated on the area associated with to-be-retrieved information than when fixating on another area. Our results provide evidence for a functional relationship between LAN and memory retrieval that extends to verbal information.

The Construction of Infrastructure for Library's Digital Document Telecommunications.

ERIC Educational Resources Information Center

Changxing, Ying; Zuzao, Lin

This paper discusses the construction of the infrastructure for libraries' digital document telecommunications. The first section describes the topologies of the library LAN (Local Area Network) cabling system, including the main characteristics of the LAN and three classical topologies typically used with LANs, i.e., the bus, star, and ring…

Exercise attenuates the metabolic effects of dim light at night.

PubMed

Fonken, Laura K; Meléndez-Fernández, O Hecmarie; Weil, Zachary M; Nelson, Randy J

2014-01-30

Most organisms display circadian rhythms that coordinate complex physiological and behavioral processes to optimize energy acquisition, storage, and expenditure. Disruptions to the circadian system with environmental manipulations such as nighttime light exposure alter metabolic energy homeostasis. Exercise is known to strengthen circadian rhythms and to prevent weight gain. Therefore, we hypothesized providing mice a running wheel for voluntary exercise would buffer against the effects of light at night (LAN) on weight gain. Mice were maintained in either dark (LD) or dim (dLAN) nights and provided either a running wheel or a locked wheel. Mice exposed to dim, rather than dark, nights increased weight gain. Access to a functional running wheel prevented body mass gain in mice exposed to dLAN. Voluntary exercise appeared to limit weight gain independently of rescuing changes to the circadian system caused by dLAN; increases in daytime food intake induced by dLAN were not diminished by increased voluntary exercise. Furthermore, although all of the LD mice displayed a 24h rhythm in wheel running, nearly half (4 out of 9) of the dLAN mice did not display a dominant 24h rhythm in wheel running. These results indicate that voluntary exercise can prevent weight gain induced by dLAN without rescuing circadian rhythm disruptions. © 2013.

Fault-Tolerant Local-Area Network

NASA Technical Reports Server (NTRS)

Morales, Sergio; Friedman, Gary L.

1988-01-01

Local-area network (LAN) for computers prevents single-point failure from interrupting communication between nodes of network. Includes two complete cables, LAN 1 and LAN 2. Microprocessor-based slave switches link cables to network-node devices as work stations, print servers, and file servers. Slave switches respond to commands from master switch, connecting nodes to two cable networks or disconnecting them so they are completely isolated. System monitor and control computer (SMC) acts as gateway, allowing nodes on either cable to communicate with each other and ensuring that LAN 1 and LAN 2 are fully used when functioning properly. Network monitors and controls itself, automatically routes traffic for efficient use of resources, and isolates and corrects its own faults, with potential dramatic reduction in time out of service.

Dim light at night interacts with intermittent hypoxia to alter cognitive and affective responses.

PubMed

Aubrecht, Taryn G; Weil, Zachary M; Magalang, Ulysses J; Nelson, Randy J

2013-07-01

Obstructive sleep apnea (OSA) and dim light at night (dLAN) have both been independently associated with alterations in mood and cognition. We aimed to determine whether dLAN would interact with intermittent hypoxia (IH), a condition characteristic of OSA, to alter the behavioral, cognitive, and affective responses. Adult male mice were housed in either standard lighting conditions (14:10-h light-dark cycle; 150 lux:0 lux) or dLAN (150 lux:5 lux). Mice were then exposed to IH (15 cycles/h, 8 h/day, FiO2 nadir of 5%) for 3 wk, then tested in assays of affective and cognitive responses; brains were collected for dendritic morphology and PCR analysis. Exposure to dLAN and IH increased anxiety-like behaviors, as assessed in the open field, elevated plus maze, and the light/dark box. dLAN and IH increased depressive-like behaviors in the forced swim test. IH impaired learning and memory performance in the passive avoidance task; however, no differences were observed in spatial working memory, as assessed by y-maze or object recognition. IH combined with dLAN decreased cell body area in the CA1 and CA3 regions of the hippocampus. Overall, IH decreased apical spine density in the CA3, whereas dLAN decreased spine density in the CA1 of the hippocampus. TNF-α gene expression was not altered by IH or lighting condition, whereas VEGF expression was increased by dLAN. The combination of IH and dLAN provokes negative effects on hippocampal dendritic morphology, affect, and cognition, suggesting that limiting nighttime exposure to light in combination with other established treatments may be of benefit to patients with OSA.

Dim light at night interacts with intermittent hypoxia to alter cognitive and affective responses

PubMed Central

Weil, Zachary M.; Magalang, Ulysses J.; Nelson, Randy J.

2013-01-01

Obstructive sleep apnea (OSA) and dim light at night (dLAN) have both been independently associated with alterations in mood and cognition. We aimed to determine whether dLAN would interact with intermittent hypoxia (IH), a condition characteristic of OSA, to alter the behavioral, cognitive, and affective responses. Adult male mice were housed in either standard lighting conditions (14:10-h light-dark cycle; 150 lux:0 lux) or dLAN (150 lux:5 lux). Mice were then exposed to IH (15 cycles/h, 8 h/day, FiO2 nadir of 5%) for 3 wk, then tested in assays of affective and cognitive responses; brains were collected for dendritic morphology and PCR analysis. Exposure to dLAN and IH increased anxiety-like behaviors, as assessed in the open field, elevated plus maze, and the light/dark box. dLAN and IH increased depressive-like behaviors in the forced swim test. IH impaired learning and memory performance in the passive avoidance task; however, no differences were observed in spatial working memory, as assessed by y-maze or object recognition. IH combined with dLAN decreased cell body area in the CA1 and CA3 regions of the hippocampus. Overall, IH decreased apical spine density in the CA3, whereas dLAN decreased spine density in the CA1 of the hippocampus. TNF-α gene expression was not altered by IH or lighting condition, whereas VEGF expression was increased by dLAN. The combination of IH and dLAN provokes negative effects on hippocampal dendritic morphology, affect, and cognition, suggesting that limiting nighttime exposure to light in combination with other established treatments may be of benefit to patients with OSA. PMID:23657638

Combined effects of exposure to dim light at night and fine particulate matter on C3H/HeNHsd mice.

PubMed

Hogan, Matthew K; Kovalycsik, Taylor; Sun, Qinghua; Rajagopalan, Sanjay; Nelson, Randy J

2015-11-01

Air and light pollution contribute to fetal abnormalities, increase prevalence of cancer, metabolic and cardiorespiratory diseases, and central nervous system (CNS) disorders. A component of air pollution, particulate matter, and the phenomenon of dim light at night (dLAN) both result in neuroinflammation, which has been implicated in several CNS disorders. The combinatorial role of these pollutants on health outcomes has not been assessed. Male C3H/HeNHsd mice, with intact melatonin production, were used to model humans exposed to circadian disruption by dLAN and contaminated environmental air. We hypothesized exposure to 2.5 μm of particulate matter (PM2.5) and dLAN (5lx) combines to upregulate neuroinflammatory cytokine expression and alter hippocampal morphology compared to mice exposed to filtered air (FA) and housed under dark nights (LD). We also hypothesized that exposure to PM2.5 and dLAN provokes anxiety-like and depressive-like responses. For four weeks, four groups of mice were simultaneously exposed to ambient concentrated PM2.5 or FA and/or dLAN or LD. Following exposure, mice underwent several behavioral assays and hippocampi were collected for qPCR and morphological analyses. Our results are generally comparable to previous PM2.5 and dLAN reports conducted on mice and implicate PM2.5 and dLAN as potential factors contributing to depression and anxiety. Short-term exposure to PM2.5 and dLAN upregulated neuroinflammatory cytokines and altered CA1 hippocampal structural changes, as well as provoked depressive-like responses (anhedonia). However, combined, PM2.5 and dLAN exposure did not have additive effects, as hypothesized, suggesting a ceiling effect of neuroinflammation may exist in response to multiple pollutants. Copyright © 2015 Elsevier B.V. All rights reserved.

Coordinating Council. Eighth Meeting: Using the Internet

NASA Technical Reports Server (NTRS)

1992-01-01

This NASA Scientific and Technical Information Program Coordinating Council meeting theme was entitled 'Using Internet'. Individual topics included STI LAN migration, NSF and NREN (National Science Foundation and the National Research and Education Network), and the New NASA Headquarters LAN. Discussions are recorded for each topic and visuals are provided for STI LAN migration and NSI - NASA Science Internet.

Effects of Dim Light at Night on Food Intake and Body Mass in Developing Mice.

PubMed

Cissé, Yasmine M; Peng, Juan; Nelson, Randy J

2017-01-01

Appropriately timed light is critical for circadian organization; exposure to dim light at night (dLAN) disrupts temporal organization of endogenous biological timing. Exposure to dLAN in adult mice is associated with elevated body mass and changes in metabolism putatively driven by voluntary changes in the time of food intake. We predicted that exposure of young mice to LAN could affect adult metabolic function. At 3 weeks (Experiment 1) or 5 weeks (Experiment 2) of age, mice were either maintained in standard light-dark (DARK) cycles or exposed to nightly dLAN (5 lux). In the first two experiments, food intake and locomotor activity were assessed after 4 weeks and a glucose tolerance test was administered after 6 weeks in experimental lighting conditions. In Experiment 3, tissues were collected around the clock at 6 h intervals to investigate rhythmic hepatic clock gene expression in mice exposed to dLAN from 3 or 5 weeks of age. Male and female mice exposed to dLAN beginning at 3 weeks of age displayed similar growth rates and body mass to DARK-reared offspring, despite increasing day-time food intake. Exposure to dLAN beginning at 5 weeks of age increased body mass and daytime food intake in male, but not female, mice. Consistent with the body mass phenotype, clock gene expression was unaltered in the liver. In contrast to adults, dLAN exposure during the development of the peripheral circadian system has sex- and development-dependent effects on body mass gain.

Measuring Light at Night and Melatonin Levels in Shift Workers: A Review of the Literature.

PubMed

Hunter, Claudia M; Figueiro, Mariana G

2017-07-01

Shift work, especially that involving rotating and night shifts, is associated with an increased risk of diseases, including cancer. Attempts to explain the association between shift work and cancer in particular have focused on the processes of melatonin production and suppression. One hypothesis postulates that exposure to light at night (LAN) suppresses melatonin, whose production is known to slow the development of cancerous cells, while another proposes that circadian disruption associated with shift work, and not just LAN, increases health risks. This review focuses on six studies that employed quantitative measurement of LAN and melatonin levels to assess cancer risks in shift workers. These studies were identified via searching the PubMed database for peer-reviewed, English-language articles examining the links between shift work, LAN, and disease using the terms light at night, circadian disruption, health, risk, cancer, shift work, or rotating shift. While the results indicate a growing consensus on the relationship between disease risks (particularly cancer) and circadian disruption associated with shift work, the establishment of a direct link between LAN and disease has been impeded by contradictory studies and a lack of consistent, quantitative methods for measuring LAN in the research to date. Better protocols for assessing personal LAN exposure are required, particularly those employing calibrated devices that measure and sample exposure to workplace light conditions, to accurately assess LAN's effects on the circadian system and disease. Other methodologies, such as measuring circadian disruption and melatonin levels in the field, may also help to resolve discrepancies in the findings.

Two new species and new records of chiggers (Acari: Leeuwenhoekiidae,
Trombiculidae) from birds in Vietnam.

PubMed

Kaluz, Stanislav K; Hung, Nguyen Manh; Capek, Miroslav; Literak, Ivan

2016-01-11

A total of 12 chigger species (Acariformes: Trombiculidae) occurred on 7 bird species in Vietnam. Two new species, namely Neoschoengastia vietnamensis sp. nov. and Hypogastia stekolnikovi sp. nov. are described, figured and compared with similar species placed in relevant genera using differential diagnoses of related species. Figures and diagnosis of Leptotrombidium taiyuanense Tian and Wen, 1984 are added. Odontacarus audy (Radford, 1946), Leptotrombidium allosetum Wang, Liao and Lin, 1981, L. taiyuanense, Leptotrombidium hanseni Traub and Lakshana, 1966, Leptotrombidium kunshui Wen and Xiang, 1984, Leptotrombidium paradux Vercammen-Grandjean and Langston, 1976, Leptotrombidium turdicola Vercammen-Grandjean and Langston, 1976, Neotrombicula elegans Schluger, 1966 and Neoschoengastia longitar-salis Schluger and Belskaya, 1966 were recorded in Vietnam for the first time.

RETRACTED: Relationship between the ACE I/D gene polymorphism and T1DN susceptibility/risk of T1DM developing into T1DN in the Caucasian population.

PubMed

Zhou, Tian-Biao; Guo, Xue-Feng; Jiang, Zongpei; Li, Hong-Yan

2015-12-01

The following article has been included in a multiple retraction: Tian-Biao Zhou, Xue-Feng Guo, Zongpei Jiang, and Hong-Yan Li Relationship between the ACE I/D gene polymorphism and T1DN susceptibility/risk of T1DM developing into T1DN in the Caucasian population Journal of Renin-Angiotensin-Aldosterone System 1470320314563425, first published on February 1, 2015 doi: 10.1177/1470320314563425 This article has been retracted at the request of the Editors and the Publisher. After conducting a thorough investigation, SAGE found that the submitting authors of a number of papers published in the Journal of the Renin-Angiotensin Aldosterone System ( JRAAS) (listed below) had supplied fabricated contact details for their nominated reviewers. The Editors accepted these papers based on the reports supplied by the individuals using these fake reviewer email accounts. After concluding that the peer review process was therefore seriously compromised, SAGE and the journal Editors have decided to retract all affected articles. Online First articles (these articles will not be published in an issue) Wenzhuang Tang, Tian-Biao Zhou, and Zongpei Jiang Association of the angiotensinogen M235T gene polymorphism with risk of diabetes mellitus developing into diabetic nephropathy Journal of Renin-Angiotensin-Aldosterone System 1470320314563426, first published on December 18, 2014 doi: 10.1177/1470320314563426 Tian-Biao Zhou, Hong-Yan Li, Zong-Pei Jiang, Jia-Fan Zhou, Miao-Fang Huang, and Zhi-Yang Zhou Role of renin-angiotensin-aldosterone system inhibitors in radiation nephropathy Journal of Renin-Angiotensin-Aldosterone System 1470320314563424, first published on December 18, 2014 doi: 10.1177/1470320314563424 Weiqiang Zhong, Zongpei Jiang, and Tian-Biao Zhou Association between the ACE I/D gene polymorphism and T2DN susceptibility: The risk of T2DM developing into T2DN in the Asian population Journal of Renin-Angiotensin-Aldosterone System 1470320314566019, first published on January

RETRACTED: Association between the ACE I/D gene polymorphism and T2DN susceptibility: The risk of T2DM developing into T2DN in the Asian population.

PubMed

Zhong, Weiqiang; Jiang, Zongpei; Zhou, Tian-Biao

2015-12-01

This article has been included in a multiple retraction: Weiqiang Zhong, Zongpei Jiang, and Tian-Biao Zhou Association between the ACE I/D gene polymorphism and T2DN susceptibility: The risk of T2DM developing into T2DN in the Asian population Journal of Renin-Angiotensin-Aldosterone System 1470320314566019, first published on January 26, 2015 doi: 10.1177/1470320314566019 This article has been retracted at the request of the Editors and the Publisher. After conducting a thorough investigation, SAGE found that the submitting authors of a number of papers published in the Journal of the Renin-Angiotensin Aldosterone System ( JRAAS) (listed below) had supplied fabricated contact details for their nominated reviewers. The Editors accepted these papers based on the reports supplied by the individuals using these fake reviewer email accounts. After concluding that the peer review process was therefore seriously compromised, SAGE and the journal Editors have decided to retract all affected articles. Online First articles (these articles will not be published in an issue) Wenzhuang Tang, Tian-Biao Zhou, and Zongpei Jiang Association of the angiotensinogen M235T gene polymorphism with risk of diabetes mellitus developing into diabetic nephropathy Journal of Renin-Angiotensin-Aldosterone System 1470320314563426, first published on December 18, 2014 doi: 10.1177/1470320314563426 Tian-Biao Zhou, Hong-Yan Li, Zong-Pei Jiang, Jia-Fan Zhou, Miao-Fang Huang, and Zhi-Yang Zhou Role of renin-angiotensin-aldosterone system inhibitors in radiation nephropathy Journal of Renin-Angiotensin-Aldosterone System 1470320314563424, first published on December 18, 2014 doi: 10.1177/1470320314563424 Weiqiang Zhong, Zongpei Jiang, and Tian-Biao Zhou Association between the ACE I/D gene polymorphism and T2DN susceptibility: The risk of T2DM developing into T2DN in the Asian population Journal of Renin-Angiotensin-Aldosterone System 1470320314566019, first published on January 26, 2015 doi: 10

Temporal variation and source identification of black carbon at Lin'an and Longfengshan regional background stations in China

NASA Astrophysics Data System (ADS)

Cheng, Siyang; Wang, Yaqiang; An, Xingqin

2017-12-01

Black carbon (BC) is a component of fine particulate matter (PM2.5), associated with climate, weather, air quality, and people's health. However, studies on temporal variation of atmospheric BC concentration at background stations in China and its source area identification are lacking. In this paper, we use 2-yr BC observations from two background stations, Lin'an (LAN) and Longfengshan (LFS), to perform the investigation. The results show that the mean diurnal variation of BC has two significant peaks at LAN while different characteristics are found in the BC variation at LFS, which are probably caused by the difference in emission source contributions. Seasonal variation of monthly BC shows double peaks at LAN but a single peak at LFS. The annual mean concentrations of BC at LAN and LFS decrease by 1.63 and 0.26 μg m-3 from 2009 to 2010, respectively. The annual background concentration of BC at LAN is twice higher than that at LFS. The major source of the LAN BC is industrial emission while the source of the LFS BC is residential emission. Based on transport climatology on a 7-day timescale, LAN and LFS stations are sensitive to surface emissions respectively in belt or approximately circular area, which are dominated by summer monsoon or colder land air flows in Northwest China. In addition, we statistically analyze the BC source regions by using BC observation and FLEXible PARTicle dispersion model (FLEXPART) simulation. In summer, the source regions of BC are distributed in the northwest and south of LAN and the southwest of LFS. Low BC concentration is closely related to air mass from the sea. In winter, the source regions of BC are concentrated in the west and south of LAN and the northeast of the threshold area of s tot at LFS. The cold air mass in the northwest plays an important role in the purification of atmospheric BC. On a yearly scale, sources of BC are approximately from five provinces in the northwest/southeast of LAN and the west of LFS. These

Chronic dim light at night provokes reversible depression-like phenotype: possible role for TNF.

PubMed

Bedrosian, T A; Weil, Z M; Nelson, R J

2013-08-01

The prevalence of major depression has increased in recent decades and women are twice as likely as men to develop the disorder. Recent environmental changes almost certainly have a role in this phenomenon, but a complete set of contributors remains unspecified. Exposure to artificial light at night (LAN) has surged in prevalence during the past 50 years, coinciding with rising rates of depression. Chronic exposure to LAN is linked to increased risk of breast cancer, obesity and mood disorders, although the relationship to mood is not well characterized. In this study, we investigated the effects of chronic exposure to 5 lux LAN on depression-like behaviors in female hamsters. Using this model, we also characterized hippocampal brain-derived neurotrophic factor expression and hippocampal dendritic morphology, and investigated the reversibility of these changes 1, 2 or 4 weeks following elimination of LAN. Furthermore, we explored the mechanism of action, focusing on hippocampal proinflammatory cytokines given their dual role in synaptic plasticity and the pathogenesis of depression. Using reverse transcription-quantitative PCR, we identified a reversible increase in hippocampal tumor necrosis factor (TNF), but not interleukin-1β, mRNA expression in hamsters exposed to LAN. Direct intracerebroventricular infusion of a dominant-negative inhibitor of soluble TNF, XPro1595, prevented the development of depression-like behavior under LAN, but had no effect on dendritic spine density in the hippocampus. These results indicate a partial role for TNF in the reversible depression-like phenotype observed under chronic dim LAN. Recent environmental changes, such as LAN exposure, may warrant more attention as possible contributors to rising rates of mood disorders.

Security analysis and improvement of a privacy authentication scheme for telecare medical information systems.

PubMed

Wu, Fan; Xu, Lili

2013-08-01

Nowadays, patients can gain many kinds of medical service on line via Telecare Medical Information Systems(TMIS) due to the fast development of computer technology. So security of communication through network between the users and the server is very significant. Authentication plays an important part to protect information from being attacked by malicious attackers. Recently, Jiang et al. proposed a privacy enhanced scheme for TMIS using smart cards and claimed their scheme was better than Chen et al.'s. However, we have showed that Jiang et al.'s scheme has the weakness of ID uselessness and is vulnerable to off-line password guessing attack and user impersonation attack if an attacker compromises the legal user's smart card. Also, it can't resist DoS attack in two cases: after a successful impersonation attack and wrong password input in Password change phase. Then we propose an improved mutual authentication scheme used for a telecare medical information system. Remote monitoring, checking patients' past medical history record and medical consultant can be applied in the system where information transmits via Internet. Finally, our analysis indicates that the suggested scheme overcomes the disadvantages of Jiang et al.'s scheme and is practical for TMIS.

Antitumor effect of combination of the inhibitors of two new oncotargets: proton pumps and reverse transcriptase.

PubMed

Lugini, Luana; Sciamanna, Ilaria; Federici, Cristina; Iessi, Elisabetta; Spugnini, Enrico Pierluigi; Fais, Stefano

2017-01-17

Tumor therapy needs new approaches in order to improve efficacy and reduce toxicity of the current treatments. The acidic microenvironment and the expression of high levels of endogenous non-telomerase reverse transcriptase (RT) are common features of malignant tumor cells. The anti-acidic proton pump inhibitor Lansoprazole (LAN) and the non-nucleoside RT inhibitor Efavirenz (EFV) have shown independent antitumor efficacy. LAN has shown to counteract drug tumor resistance. We tested the hypothesis that combination of LAN and EFV may improve the overall antitumor effects. We thus pretreated human metastatic melanoma cells with LAN and then with EFV, both in 2D and 3D spheroid models. We evaluated the treatment effect by proliferation and cell death/apoptosis assays in classical and in pulse administration experiments. The action of EFV was negatively affected by the tumor microenvironmental acidity, and LAN pretreatment overcame the problem. LAN potentiated the cytotoxicity of EFV to melanoma cells and, when administered during the drug interruption period, prevented the replacement of tumor cell growth.This study supports the implementation of the current therapies with combination of Proton Pumps and Reverse Transcriptase inhibitors.

Antitumor effect of combination of the inhibitors of two new oncotargets: proton pumps and reverse transcriptase

PubMed Central

Lugini, Luana; Sciamanna, Ilaria; Federici, Cristina; Iessi, Elisabetta; Spugnini, Enrico Pierluigi; Fais, Stefano

2017-01-01

Tumor therapy needs new approaches in order to improve efficacy and reduce toxicity of the current treatments. The acidic microenvironment and the expression of high levels of endogenous non-telomerase reverse transcriptase (RT) are common features of malignant tumor cells. The anti-acidic proton pump inhibitor Lansoprazole (LAN) and the non-nucleoside RT inhibitor Efavirenz (EFV) have shown independent antitumor efficacy. LAN has shown to counteract drug tumor resistance. We tested the hypothesis that combination of LAN and EFV may improve the overall antitumor effects. We thus pretreated human metastatic melanoma cells with LAN and then with EFV, both in 2D and 3D spheroid models. We evaluated the treatment effect by proliferation and cell death/apoptosis assays in classical and in pulse administration experiments. The action of EFV was negatively affected by the tumor microenvironmental acidity, and LAN pretreatment overcame the problem. LAN potentiated the cytotoxicity of EFV to melanoma cells and, when administered during the drug interruption period, prevented the replacement of tumor cell growth. This study supports the implementation of the current therapies with combination of Proton Pumps and Reverse Transcriptase inhibitors. PMID:27926505

Chronic exposure to dim light at night suppresses immune responses in Siberian hamsters.

PubMed

Bedrosian, Tracy A; Fonken, Laura K; Walton, James C; Nelson, Randy J

2011-06-23

Species have been adapted to specific niches optimizing survival and reproduction; however, urbanization by humans has dramatically altered natural habitats. Artificial light at night (LAN), termed 'light pollution', is an often overlooked, yet increasing disruptor of habitats, which perturbs physiological processes that rely on precise light information. For example, LAN alters the timing of reproduction and activity in some species, which decreases the odds of successful breeding and increases the threat of predation for these individuals, leading to reduced fitness. LAN also suppresses immune function, an important proxy for survival. To investigate the impact of LAN in a species naive to light pollution in its native habitat, immune function was examined in Siberian hamsters derived from wild-caught stock. After four weeks exposure to dim LAN, immune responses to three different challenges were assessed: (i) delayed-type hypersensitivity (DTH), (ii) lipopolysaccharide-induced fever, and (iii) bactericide activity of blood. LAN suppressed DTH response and reduced bactericide activity of blood after lipopolysaccharide treatment, in addition to altering daily patterns of locomotor activity, suggesting that human encroachment on habitats via night-time lighting may inadvertently compromise immune function and ultimately fitness.

Role of Light in Breast Cancer

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stevens, Richard G.; Anderson, Larry E.; Michael F. Holick

1999-06-14

There is a prima facie reason for studying possible biological effects of light-at-night (LAN) in the laboratory and human health effects in the population at large: LAN from the use of electricity represent exposures in the human environment not previously encountered in human evolution. These LAN exposures are pervasive in industrialized societies, and any adverse health effects from them could result in considerable consequences for the population. In particular, exposures of pregnant women to LAN that might result in increased estrogen exposure in utero to their child may lead to increased tissue mass and increased lifetime risk of breast cancermore » of the child.« less

Light at night and melatonin have opposite effects on breast cancer tumors in mice assessed by growth rates and global DNA methylation.

PubMed

Schwimmer, Hagit; Metzer, Avishag; Pilosof, Yonit; Szyf, Moshe; Machnes, Ziv M; Fares, Fuad; Harel, Orna; Haim, Abraham

2014-02-01

Light-at-night (LAN) is a worldwide problem co-distributed with breast cancer prevalence. We hypothesized that exposure to LAN is coincided with a decreased melatonin (MLT) secretion level, followed by epigenetic modifications and resulted in higher breast cancer tumors growth-rate. Accordingly, we studied the effect of LAN exposure and exogenous MLT on breast cancer tumors growth-rate. 4T1 cells were inoculated into BALB/c short day-acclimated mice, resulting in tumors growth. Growth rates were followed under various light exposures and global DNA methylations were measured. Results demonstrated the positive effect of LAN on tumors growth-rate, reversed by MLT through global DNA methylation.

Low Incidence of Gastrointestinal Adverse Events Over Time with a Fixed-Ratio Combination of Insulin Glargine and Lixisenatide vs Lixisenatide Alone.

PubMed

Trujillo, Jennifer M; Roberts, Michelle; Dex, Terry; Chao, Jason; John White, Pa-C; LaSalle, James

2018-06-19

This post hoc analysis of gastrointestinal (GI) adverse events (AEs) from the phase 3 LixiLan-L (NCT02058160) and LixiLan-O (NCT02058147) trials aimed to determine the frequency and timing of nausea, vomiting, and diarrhea for iGlarLixi, a titratable, fixed-ratio combination of insulin glargine 100 U/mL (iGlar) and lixisenatide, vs iGlar alone or iGlar and lixisenatide alone, in patients with type 2 diabetes uncontrolled with oral antidiabetes drugs (OADs) or basal insulin ± OADs. In iGlarLixi-treated patients, the rate of GI AEs during initial weeks of treatment was lower vs patients treated with lixisenatide alone (9.6% and 11.7% of iGlarLixi-treated patients in LixiLan-L and LixiLan-O, respectively, vs 27.5% of lixisenatide-treated patients in LixiLan-O). Beyond Day 60, these rates were generally low and similar to those of lixisenatide. These lower rates are likely due to the gradual titration of lixisenatide in iGlarLixi. Median durations of intermittent GI AEs in the iGlarLixi arms were 6.0, 2.0 and 2.5 days (LixiLan-L), and 5.0, 1.0 and 3.5 days (LixiLan-O), respectively. iGlarLixi-associated GI AEs were transient, mostly mild or moderate in severity, and occurred mainly during initial titration. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

The Effects of Blast Trauma (Impulse Noise) on Hearing: A Parametric Study

DTIC Science & Technology

1988-07-22

8217 q 2~~L m AALLA LAN LALALA v O 0- N( N N r4OD r: el LAr:r: v) 0n n LALALAL LAn LA vLnLA LAL LO 55 0 w * . . * 0 * * * * 0 w4 I n 4)L nL nr n nL nL nr...0ý LnLn LLLA r-in toN fLn Ln oA LA(n C.* * . . . * 10 C0 -. ~~0, NN m- AULA v *- r4~~~ ~- -1 H~i-r -4C (’eN r4* ntni L Len LAo mS- rLAn f m 04 0D LAAALL...C r-: 4 ýr- r- r-o8*i c oG o - G D% vooi %Vr- r- -4 ’-4 ( DE 0n u) tn A tn r- gn Ln .An inLn .n c4 0) 91 * . . ** Nn * LAn’Ln~ Ln to~ uiL . n nL n 040

Improvement of a uniqueness-and-anonymity-preserving user authentication scheme for connected health care.

PubMed

Xie, Qi; Liu, Wenhao; Wang, Shengbao; Han, Lidong; Hu, Bin; Wu, Ting

2014-09-01

Patient's privacy-preserving, security and mutual authentication between patient and the medical server are the important mechanism in connected health care applications, such as telecare medical information systems and personally controlled health records systems. In 2013, Wen showed that Das et al.'s scheme is vulnerable to the replay attack, user impersonation attacks and off-line guessing attacks, and then proposed an improved scheme using biometrics, password and smart card to overcome these weaknesses. However, we show that Wen's scheme is still vulnerable to off-line password guessing attacks, does not provide user's anonymity and perfect forward secrecy. Further, we propose an improved scheme to fix these weaknesses, and use the applied pi calculus based formal verification tool ProVerif to prove the security and authentication.

Southeastern U.S.A. Continental Shelf Respiratory Rates Revisited

NASA Technical Reports Server (NTRS)

Sheldon, Joan E.; Griffith, Peter C.; Peters Francesc; Sheldon, Wade M., Jr.; Blanton, Jackson O.; Amft, Julie; Pomeroy, Lawrence R.

2010-01-01

Respiratory rates on the U. S. southeastern continental shelf have been estimated several times by different investigators, most recently by Jiang et al. (Biogeochemistry 98:101-113, 2010) who report lower mean rates thanwere found in earlier work and attribute the differences to analytical error in all methods used in earlier studies. The differences are, instead, attributable to the differences in the geographical scope of the studies. The lower estimates of regional organic carbon flux of Jiang et al. (Biogeochemistry 98:101-113, 2010) are a consequence of their extrapolation of data from a small portion of the shelf to the entire South Atlantic Bight. This comment examines the methodologies used as well as the variability of respiratory rates in this region over space and time.

Dim light at night disrupts the short-day response in Siberian hamsters.

PubMed

Ikeno, Tomoko; Weil, Zachary M; Nelson, Randy J

2014-02-01

Photoperiodic regulation of physiology, morphology, and behavior is crucial for many animals to survive seasonally variable conditions unfavorable for reproduction and survival. The photoperiodic response in mammals is mediated by nocturnal secretion of melatonin under the control of a circadian clock. However, artificial light at night caused by recent urbanization may disrupt the circadian clock, as well as the photoperiodic response by blunting melatonin secretion. Here we examined the effect of dim light at night (dLAN) (5lux of light during the dark phase) on locomotor activity rhythms and short-day regulation of reproduction, body mass, pelage properties, and immune responses of male Siberian hamsters. Short-day animals reduced gonadal and body mass, decreased spermatid nuclei and sperm numbers, molted to a whiter pelage, and increased pelage density compared to long-day animals. However, animals that experienced short days with dLAN did not show these short-day responses. Moreover, short-day specific immune responses were altered in dLAN conditions. The nocturnal activity pattern was blunted in dLAN hamsters, consistent with the observation that dLAN changed expression of the circadian clock gene, Period1. In addition, we demonstrated that expression levels of genes implicated in the photoperiodic response, Mel-1a melatonin receptor, Eyes absent 3, thyroid stimulating hormone receptor, gonadotropin-releasing hormone, and gonadotropin-inhibitory hormone, were higher in dLAN animals than those in short-day animals. These results suggest that dLAN disturbs the circadian clock function and affects the molecular mechanisms of the photoperiodic response. Copyright © 2013 Elsevier Inc. All rights reserved.

Freshwater Vulnerability beyond Local Water Stress: Heterogeneous Effects of Water-Electricity Nexus Across the Continental United States.

PubMed

Wang, Ranran; Zimmerman, Julie B; Wang, Chunyan; Font Vivanco, David; Hertwich, Edgar G

2017-09-05

Human health and economic prosperity are vulnerable to freshwater shortage in many parts of the world. Despite a growing literature that examines the freshwater vulnerability in various spatiotemporal contexts, existing knowledge has been conventionally constrained by a territorial perspective. On the basis of spatial analyses of monthly water and electricity flows across 2110 watersheds and three interconnected power systems, this study investigates the water-electricity nexus (WEN)'s transboundary effects on freshwater vulnerability in the continental United States in 2014. The effects are shown to be considerable and heterogeneous across time and space. For at least one month a year, 58 million people living in water-abundant watersheds were exposed to additional freshwater vulnerability by relying on electricity generated by freshwater-cooled thermal energy conversion cycles in highly stressed watersheds; for 72 million people living in highly stressed watersheds, their freshwater vulnerability was mitigated by using imported electricity generated in water-abundant watersheds or power plants running dry cooling or using nonfreshwater for cooling purposes. On the country scale, the mitigation effects were the most significant during September and October, while the additional freshwater vulnerability was more significant in February, March, and December. Due to the WEN's transboundary effects, overall, the freshwater vulnerability was slightly worsened within the Eastern Interconnection, substantially improved within the Western Interconnection, and least affected within the ERCOT Interconnection.

Highly turbulent solutions of the Lagrangian-averaged Navier-Stokes alpha model and their large-eddy-simulation potential.

PubMed

Pietarila Graham, Jonathan; Holm, Darryl D; Mininni, Pablo D; Pouquet, Annick

2007-11-01

We compute solutions of the Lagrangian-averaged Navier-Stokes alpha - (LANS alpha ) model for significantly higher Reynolds numbers (up to Re approximately 8300 ) than have previously been accomplished. This allows sufficient separation of scales to observe a Navier-Stokes inertial range followed by a second inertial range specific to the LANS alpha model. Both fully helical and nonhelical flows are examined, up to Reynolds numbers of approximately 1300. Analysis of the third-order structure function scaling supports the predicted l3 scaling; it corresponds to a k-1 scaling of the energy spectrum for scales smaller than alpha. The energy spectrum itself shows a different scaling, which goes as k1. This latter spectrum is consistent with the absence of stretching in the subfilter scales due to the Taylor frozen-in hypothesis employed as a closure in the derivation of the LANS alpha model. These two scalings are conjectured to coexist in different spatial portions of the flow. The l3 [E(k) approximately k-1] scaling is subdominant to k1 in the energy spectrum, but the l3 scaling is responsible for the direct energy cascade, as no cascade can result from motions with no internal degrees of freedom. We demonstrate verification of the prediction for the size of the LANS alpha attractor resulting from this scaling. From this, we give a methodology either for arriving at grid-independent solutions for the LANS alpha model, or for obtaining a formulation of the large eddy simulation optimal in the context of the alpha models. The fully converged grid-independent LANS alpha model may not be the best approximation to a direct numerical simulation of the Navier-Stokes equations, since the minimum error is a balance between truncation errors and the approximation error due to using the LANS alpha instead of the primitive equations. Furthermore, the small-scale behavior of the LANS alpha model contributes to a reduction of flux at constant energy, leading to a shallower energy

Technical Knowledge, Cultural Practices and Social Boundaries: Wan-Nan Scholars and the Recasting of Jesuit Astronomy, 1600-1800

NASA Astrophysics Data System (ADS)

Chu, Ping-Yi.

Taking four Wan-nan Confucian scholars--Yang Kuang -hsien, Mei Wen-ting, Chiang Yung and Tai Chen--as examples, this dissertation studies how an immigrant Jesuit scientific community built and defended itself in a specialized institutional niche located at the Ch'ing court and how a defeated Chinese scientific tradition successfully survived by occupying a broader cultural space, with the Manchu emperor in between. Special attention is paid to how these four Confucian scholars constructed social boundaries between the Chinese and the Westerners in their astronomical discourses and how they domesticated Western astronomy in order to fit the Chinese cultural conditions situated in the power structure built by the Manchus. This inquiry begins with a brief introduction of Wan-nan and the Wan-nan school. I then discuss how the Jesuits legitimated their knowledge during the Ming -Ch'ing transition, and how Jesuit astronomy was situated within the power nexus between the Confucian literati and the emperors. The next chapter focuses on Yang Kuang-hsien and his challenges to the Jesuits. I examine his strategies and the power structure in which Yang carried out his challenge to the Jesuits. The fourth and fifth chapters investigate how Mei Wen-ting restructured the relationship between Confucianism and astronomy. The former chapter focuses on Mei's social networking and his ambivalence towards the Ming and Ch'ing dynasties, on the one hand, and towards Chinese and Western learning on the other. The latter chapter deals with how Mei Wen-ting recast Chinese astronomical tradition and Confucianism. In the sixth chapter, I will compare the fame of Chiang Yung and Tai Chen in order to demonstrate how astronomy was practiced in evidential studies after Mei Wen-ting, and how evidential studies itself conveyed an ideological construction of the other. Through integrating Western astronomy with indigenous tradition while exorcising the otherness contained within the cultural package

General Methodology Combining Engineering Optimization of Primary HVAC and R Plants with Decision Analysis Methods--Part II: Uncertainty and Decision Analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jiang, Wei; Reddy, T. A.; Gurian, Patrick

2007-01-31

A companion paper to Jiang and Reddy that presents a general and computationally efficient methodology for dyanmic scheduling and optimal control of complex primary HVAC&R plants using a deterministic engineering optimization approach.

An abstract model of rogue code insertion into radio frequency wireless networks. The effects of computer viruses on the Program Management Office

NASA Astrophysics Data System (ADS)

Feudo, Christopher V.

1994-04-01

This dissertation demonstrates that inadequately protected wireless LANs are more vulnerable to rogue program attack than traditional LANs. Wireless LANs not only run the same risks as traditional LANs, but they also run additional risks associated with an open transmission medium. Intruders can scan radio waves and, given enough time and resources, intercept, analyze, decipher, and reinsert data into the transmission medium. This dissertation describes the development and instantiation of an abstract model of the rogue code insertion process into a DOS-based wireless communications system using radio frequency (RF) atmospheric signal transmission. The model is general enough to be applied to widely used target environments such as UNIX, Macintosh, and DOS operating systems. The methodology and three modules, the prober, activator, and trigger modules, to generate rogue code and insert it into a wireless LAN were developed to illustrate the efficacy of the model. Also incorporated into the model are defense measures against remotely introduced rogue programs and a cost-benefit analysis that determined that such defenses for a specific environment were cost-justified.

Dim Light at Night Increases Body Mass of Female Mice

PubMed Central

Aubrecht, Taryn G.; Jenkins, Richelle; Nelson, Randy J.

2016-01-01

During the past century the prevalence of light at night has increased in parallel with obesity rates. Dim light at night (dLAN) increases body mass in male mice. However, the effects of light at night on female body mass remain unspecified. Thus, female mice were exposed to a standard light/dark (LD; 16h light at ~150 lux/8h dark at ~0 lux) cycle or to light/dim light at night (dLAN; 16h light at ~150 lux/8h dim light at ~5 lux) cycles for six weeks. Females exposed to dLAN increased the rate of change in body mass compared to LD mice despite reduced total food intake during weeks five and six, suggesting that dLAN disrupted circadian rhythms resulting in deranged metabolism. PMID:25431079

Osteoarthritis

MedlinePlus

... Knee Osteoarthritis by DY Wen, M.D.(American Family Physician 08/01/00) Shoulder Osteoarthritis: Diagnosis and Management ... Gobezie, MD, and Robert E. Boykin, MD(American Family Physician 09/01/08) Last Updated: April 1, 2014 ...

LLNL/LANS mission committee meeting

DOE Office of Scientific and Technical Information (OSTI.GOV)

Burns, Michael J

2010-12-06

Recent events continue to show the national security imperative of the global security mission: (1) Fighting Proliferation - (a) At Yongbyon, 'a modern, industrial-scale U-enrichment facility w/2000 centrifuges' seen Nov. 2010, (b) In Iran, fueling began at Bushehr while P5+1/lran talks delayed to Dec. 2010; (2) Continuing need to support the warfighter and IC - (a) tensions on the Korean peninsula, (b) primitative IEDs a challenge in Afghanistan, (c) cyber command, (d)another Georgian smuggling event; and (3) Countering terrorisms on US soil - (a) toner cartridge bomb, (b) times square bomb, (c) christmas tree bomb. Joint Technical Operations Team (JTOT)more » and Accident Response Group (ARG) elements deployed to two East Coast locations in November to work a multi-weapon scenario. LANL provided 70% of on-duty field and reconstitution teams for both Marble Challenge 11-01 and JD 11-01. There were a total of 14 deployments in FY10.« less

LanDPro: Landscape Dynamics Program

DTIC Science & Technology

2012-09-18

of Major Accomplishments............................................................... 7 1. Landscape history and response to land use change and...site potential using geologic, geomorphic, and geophysical techniques, U.S. Marine Corps Base Camp Pendleton, CA...safe, realistic military training environments while maximizing use for active training, DoD spends upwards of $100 million annually on land management

Local Area Networks (The Printout).

ERIC Educational Resources Information Center

Aron, Helen; Balajthy, Ernest

1989-01-01

Describes the Local Area Network (LAN), a project in which students used LAN-based word processing and electronic mail software as the center of a writing process approach. Discusses the advantages and disadvantages of networking. (MM)

Facilitating telecommuting : exploring the role of telecommuting intensity and differences between telecommuters and non-telecommuters.

DOT National Transportation Integrated Search

2010-06-01

Walls, Safirova and Jiang (2007) note the paucity of studies that examine telecommuting among individuals across organizations and studies that compare telecommuters with non-telecommuters. This study responds to this call by gaining a deeper underst...

An Integrated Architecture for Automatic Indication, Avoidance and Profiling of Kernel Rootkit Attacks

DTIC Science & Technology

2014-08-20

ORGANIZATION REPORT NUMBER . Laf yette, IN 47907 North Carolina State University, 890 Oval Dr., Raleigh, NC 27695 ...North Carolina State University Raleigh, NC 27695 Phone: (919) 513-7835 Email: jiang@cs.ncsu.edu 1. Project Summary

Correction: Shell-isolated nanoparticle-enhanced Raman spectroscopy study of the adsorption behaviour of DNA bases on Au(111) electrode surfaces.

PubMed

Wen, Bao-Ying; Jin, Xi; Li, Yue; Wang, Ya-Hao; Li, Chao-Yu; Liang, Miao-Miao; Panneerselvam, Rajapandiyan; Xu, Qing-Chi; Wu, De-Yin; Yang, Zhi-Lin; Li, Jian-Feng; Tian, Zhong-Qun

2016-06-21

Correction for 'Shell-isolated nanoparticle-enhanced Raman spectroscopy study of the adsorption behaviour of DNA bases on Au(111) electrode surfaces' by Bao-Ying Wen et al., Analyst, 2016, DOI: 10.1039/c6an00180g.

A system for distributed intrusion detection

DOE Office of Scientific and Technical Information (OSTI.GOV)

Snapp, S.R.; Brentano, J.; Dias, G.V.

1991-01-01

The study of providing security in computer networks is a rapidly growing area of interest because the network is the medium over which most attacks or intrusions on computer systems are launched. One approach to solving this problem is the intrusion-detection concept, whose basic premise is that not only abandoning the existing and huge infrastructure of possibly-insecure computer and network systems is impossible, but also replacing them by totally-secure systems may not be feasible or cost effective. Previous work on intrusion-detection systems were performed on stand-alone hosts and on a broadcast local area network (LAN) environment. The focus of ourmore » present research is to extend our network intrusion-detection concept from the LAN environment to arbitarily wider areas with the network topology being arbitrary as well. The generalized distributed environment is heterogeneous, i.e., the network nodes can be hosts or servers from different vendors, or some of them could be LAN managers, like our previous work, a network security monitor (NSM), as well. The proposed architecture for this distributed intrusion-detection system consists of the following components: a host manager in each host; a LAN manager for monitoring each LAN in the system; and a central manager which is placed at a single secure location and which receives reports from various host and LAN managers to process these reports, correlate them, and detect intrusions. 11 refs., 2 figs.« less

Depressive-like behavior is elevated among offspring of parents exposed to dim light at night prior to mating.

PubMed

Cissé, Yasmine M; Russart, Kathryn L G; Nelson, Randy J

2017-09-01

Rates of major depressive disorder (MDD) have steadily increased over the past 50 years. Many factors have been implicated in the etiology of depressive disorders and environmental influences are being increasingly recognized. The increase in depression rates has coincided with increased artificial nighttime lighting. Exposure to light at night (LAN) has been associated with increased depressive-like behavior in rodents and decreased mood in humans. However, relatively little is known on the multigenerational effects of dLAN on affect. In this study, we exposed adult male and female Siberian hamsters (Phodopus sungorus) to either DARK (0lx) or dim LAN (5lx) for 9 weeks, then paired animals in a full factorial design; all animals were thereafter housed in dark nights. Offspring were gestated and reared in dark nights, then tested in adulthood for depressive-like behaviors and hippocampal expression of glucocorticoid (GR) and melatonin (MT1) receptor expression. Maternal exposure to dLAN decreased sucrose preference, time to first float bout in the Porsolt swim test, and GR expression in the hippocampus. Paternal exposure to dLAN increased time spent floating, and increased hippocampal GR expression. Overall, our results suggest that chronic exposure of parents to light at night has multigenerational effects on offspring depressive-like behavior. If these results pertain to humans, then our data suggest that LAN may contribute to the rapidly rising rates of major depressive disorder in industrialized and developing countries. Copyright © 2017 Elsevier Ltd. All rights reserved.

Nocturnal light exposure impairs affective responses in a wavelength-dependent manner.

PubMed

Bedrosian, Tracy A; Vaughn, Celynn A; Galan, Anabel; Daye, Ghassan; Weil, Zachary M; Nelson, Randy J

2013-08-07

Life on earth is entrained to a 24 h solar cycle that synchronizes circadian rhythms in physiology and behavior; light is the most potent entraining cue. In mammals, light is detected by (1) rods and cones, which mediate visual function, and (2) intrinsically photosensitive retinal ganglion cells (ipRGCs), which primarily project to the suprachiasmatic nucleus (SCN) in the hypothalamus to regulate circadian rhythms. Recent evidence, however, demonstrates that ipRGCs also project to limbic brain regions, suggesting that, through this pathway, light may have a role in cognition and mood. Therefore, it follows that unnatural exposure to light may have negative consequences for mood or behavior. Modern environmental lighting conditions have led to excessive exposure to light at night (LAN), and particularly to blue wavelength lights. We hypothesized that nocturnal light exposure (i.e., dim LAN) would induce depressive responses and alter neuronal structure in hamsters (Phodopus sungorus). If this effect is mediated by ipRGCs, which have reduced sensitivity to red wavelength light, then we predicted that red LAN would have limited effects on brain and behavior compared with shorter wavelengths. Additionally, red LAN would not induce c-Fos activation in the SCN. Our results demonstrate that exposure to LAN influences behavior and neuronal plasticity and that this effect is likely mediated by ipRGCs. Modern sources of LAN that contain blue wavelengths may be particularly disruptive to the circadian system, potentially contributing to altered mood regulation.

Name-Based Address Mapping for Virtual Private Networks

NASA Astrophysics Data System (ADS)

Surányi, Péter; Shinjo, Yasushi; Kato, Kazuhiko

IPv4 private addresses are commonly used in local area networks (LANs). With the increasing popularity of virtual private networks (VPNs), it has become common that a user connects to multiple LANs at the same time. However, private address ranges for LANs frequently overlap. In such cases, existing systems do not allow the user to access the resources on all LANs at the same time. In this paper, we propose name-based address mapping for VPNs, a novel method that allows connecting to hosts through multiple VPNs at the same time, even when the address ranges of the VPNs overlap. In name-based address mapping, rather than using the IP addresses used on the LANs (the real addresses), we assign a unique virtual address to each remote host based on its domain name. The local host uses the virtual addresses to communicate with remote hosts. We have implemented name-based address mapping for layer 3 OpenVPN connections on Linux and measured its performance. The communication overhead of our system is less than 1.5% for throughput and less than 0.2ms for each name resolution.

Dim light at night increases body mass of female mice.

PubMed

Aubrecht, Taryn G; Jenkins, Richelle; Nelson, Randy J

2015-05-01

During the past century, the prevalence of light at night has increased in parallel with obesity rates. Dim light at night (dLAN) increases body mass in male mice. However, the effects of light at night on female body mass remain unspecified. Thus, female mice were exposed to a standard light/dark (LD; 16 h light at ∼150 lux/8 h dark at ∼0 lux) cycle or to light/dim light at night (dLAN; 16 h light at ∼150 lux/8 h dim light at ∼5 lux) cycles for six weeks. Females exposed to dLAN increased the rate of change in body mass compared to LD mice despite reduced total food intake during weeks five and six, suggesting that dLAN disrupted circadian rhythms resulting in deranged metabolism.

Characterization and simultaneous quantification of biological aporphine alkaloids in Litsea cubeba by HPLC with hybrid ion trap time-of-flight mass spectrometry and HPLC with diode array detection.

PubMed

Zhang, Shuiying; Zhang, Qian; Guo, Qiang; Zhao, Yunfang; Gao, Xiaoli; Chai, Xingyun; Tu, Pengfei

2015-08-01

The root and rhizome of Litsea cubeba (Lour) Pers., named 'Dou-chi-jiang' in Chinese, has been traditionally used for treatment of cardiovascular and cerebrovascular diseases, rheumatic arthralgia, and other diseases in China. Aporphine alkaloids are its characteristic ingredients and responsible for its bioactivities, especially anti-inflammatory and analgesic effects. A sensitive and reliable high-performance liquid chromatography with diode array detection-tandem mass spectrometry method was developed for characterization and simultaneous determination of biological aporphine alkaloids in 'Dou-chi-jiang'. The optimized chromatographic conditions were performed on an Eclipse XDB C18 column with a gradient of acetonitrile/water containing 0.1% formic acid as the mass spectrometry mobile phase and acetonitrile/water containing 0.2% diethylamine (pH 3.10, adjusted by acetic acid) as the liquid chromatography mobile phase. The fragmentation pathways by loss of CO, ·CH3 , ·NH3 , and ·NH2 CH3 were detected as characteristic for aporphine alkaloids. Based on these characteristics, total 12 analogues were identified. The quantification method was validated in terms of linearity, precision, and accuracy for six major aporphine alkaloids, which was successfully applied for simultaneous determination in ten batches of samples. The established method is simple, rapid, and specific for characterization and quantitation of aporphine alkaloids in 'Dou-chi-jiang' and other traditional Chinese medicines rich in this kind of ingredient. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

A secure chaotic maps and smart cards based password authentication and key agreement scheme with user anonymity for telecare medicine information systems.

PubMed

Li, Chun-Ta; Lee, Cheng-Chi; Weng, Chi-Yao

2014-09-01

Telecare medicine information system (TMIS) is widely used for providing a convenient and efficient communicating platform between patients at home and physicians at medical centers or home health care (HHC) organizations. To ensure patient privacy, in 2013, Hao et al. proposed a chaotic map based authentication scheme with user anonymity for TMIS. Later, Lee showed that Hao et al.'s scheme is in no provision for providing fairness in session key establishment and gave an efficient user authentication and key agreement scheme using smart cards, in which only few hashing and Chebyshev chaotic map operations are required. In addition, Jiang et al. discussed that Hao et al.'s scheme can not resist stolen smart card attack and they further presented an improved scheme which attempts to repair the security pitfalls found in Hao et al.'s scheme. In this paper, we found that both Lee's and Jiang et al.'s authentication schemes have a serious security problem in that a registered user's secret parameters may be intentionally exposed to many non-registered users and this problem causing the service misuse attack. Therefore, we propose a slight modification on Lee's scheme to prevent the shortcomings. Compared with previous schemes, our improved scheme not only inherits the advantages of Lee's and Jiang et al.'s authentication schemes for TMIS but also remedies the serious security weakness of not being able to withstand service misuse attack.

April 27 2015 Water Cluster Leaders Meeting Report

EPA Science Inventory

The U.S. Environmental Protection Agency (EPA) partnered with the Water Economy Network (WEN) to host a Water Technology Innovation Cluster Leaders Meeting on April 27, 2015, in Pittsburgh, Pennsylvania. Approximately 75 individuals attended. The meeting was organized to bring to...

Modulation of Stat3 Alternative Splicing in Breast Cancer

DTIC Science & Technology

2010-09-01

using morpholino oligonucleotides covalently linked to an octaguanidine dendrimer (vivo- morpholinos) [54]. Since delivery of vivo-morpholino oligos...Li, and S. Jiang, Vivo-Morpholinos: a non-peptide transporter delivers Morpholinos into a wide array of mouse tissues. Biotechniques, 2008. 45(6

RETRACTED: Association of the ACE I/D gene polymorphism with sepsis susceptibility and sepsis progression.

PubMed

Yang, Chun-Hua; Zhou, Tian-Biao

2015-12-01

This article has been included in a multiple retraction: Chun-Hua Yang and Tian-Biao Zhou Association of the ACE I/D gene polymorphism with sepsis susceptibility and sepsis progression Journal of Renin-Angiotensin-Aldosterone System 1470320314568521, first published on February 3, 2015 doi: 10.1177/1470320314568521 This article has been retracted at the request of the Editors and the Publisher. After conducting a thorough investigation, SAGE found that the submitting authors of a number of papers published in the Journal of the Renin-Angiotensin Aldosterone System ( JRAAS) (listed below) had supplied fabricated contact details for their nominated reviewers. The Editors accepted these papers based on the reports supplied by the individuals using these fake reviewer email accounts. After concluding that the peer review process was therefore seriously compromised, SAGE and the journal Editors have decided to retract all affected articles. Online First articles (these articles will not be published in an issue) Wenzhuang Tang, Tian-Biao Zhou, and Zongpei Jiang Association of the angiotensinogen M235T gene polymorphism with risk of diabetes mellitus developing into diabetic nephropathy Journal of Renin-Angiotensin-Aldosterone System 1470320314563426, first published on December 18, 2014 doi: 10.1177/1470320314563426 Tian-Biao Zhou, Hong-Yan Li, Zong-Pei Jiang, Jia-Fan Zhou, Miao-Fang Huang, and Zhi-Yang Zhou Role of renin-angiotensin-aldosterone system inhibitors in radiation nephropathy Journal of Renin-Angiotensin-Aldosterone System 1470320314563424, first published on December 18, 2014 doi: 10.1177/1470320314563424 Weiqiang Zhong, Zongpei Jiang, and Tian-Biao Zhou Association between the ACE I/D gene polymorphism and T2DN susceptibility: The risk of T2DM developing into T2DN in the Asian population Journal of Renin-Angiotensin-Aldosterone System 1470320314566019, first published on January 26, 2015 doi: 10.1177/1470320314566019 Tian-Biao Zhou, Xue-Feng Guo, Zongpei

Multimedia on the Network: Has Its Time Come?

ERIC Educational Resources Information Center

Galbreath, Jeremy

1995-01-01

Examines the match between multimedia data and local area network (LAN) infrastructures. Highlights include applications for networked multimedia, i.e., asymmetric and symmetric; alternate LAN technology, including stream management software, Ethernet, FDDI (Fiber Distributed Data Interface), and ATM (Asynchronous Transfer Mode); WAN (Wide Area…

Serial Network Flow Monitor

NASA Technical Reports Server (NTRS)

Robinson, Julie A.; Tate-Brown, Judy M.

2009-01-01

Using a commercial software CD and minimal up-mass, SNFM monitors the Payload local area network (LAN) to analyze and troubleshoot LAN data traffic. Validating LAN traffic models may allow for faster and more reliable computer networks to sustain systems and science on future space missions. Research Summary: This experiment studies the function of the computer network onboard the ISS. On-orbit packet statistics are captured and used to validate ground based medium rate data link models and enhance the way that the local area network (LAN) is monitored. This information will allow monitoring and improvement in the data transfer capabilities of on-orbit computer networks. The Serial Network Flow Monitor (SNFM) experiment attempts to characterize the network equivalent of traffic jams on board ISS. The SNFM team is able to specifically target historical problem areas including the SAMS (Space Acceleration Measurement System) communication issues, data transmissions from the ISS to the ground teams, and multiple users on the network at the same time. By looking at how various users interact with each other on the network, conflicts can be identified and work can begin on solutions. SNFM is comprised of a commercial off the shelf software package that monitors packet traffic through the payload Ethernet LANs (local area networks) on board ISS.

Melatonin: a possible link between the presence of artificial light at night and reductions in biological fitness

PubMed Central

Jones, Therésa M.; Durrant, Joanna; Michaelides, Ellie B.; Green, Mark P.

2015-01-01

The mechanisms underpinning the ecological impacts of the presence of artificial night lighting remain elusive. One suspected underlying cause is that the presence of light at night (LAN) supresses nocturnal production of melatonin, a key driver of biological rhythm and a potent antioxidant with a proposed role in immune function. Here, we briefly review the evidence for melatonin as the link between LAN and changes in behaviour and physiology. We then present preliminary data supporting the potential for melatonin to act as a recovery agent mitigating the negative effects of LAN in an invertebrate. Adult crickets (Teleogryllus commodus), exposed to constant illumination, were provided with dietary melatonin (concentrations: 0, 10 or 100 µg ml−1) in their drinking water. We then compared survival, lifetime fecundity and, over a 4-week period, immune function (haemocyte concentration, lysozyme-like and phenoloxidase (PO) activity). Melatonin supplementation was able only partially to mitigate the detrimental effects of LAN: it did not improve survival or fecundity or PO activity, but it had a largely dose-dependent positive effect on haemocyte concentration and lysozyme-like activity. We discuss the implications of these relationships, as well as the usefulness of invertebrates as model species for future studies that explore the effects of LAN. PMID:25780235

Modern Foreign Languages: A Refereed International Journal of Linguistics and Applied Linguistics, 2001.

ERIC Educational Resources Information Center

Ying, Du, Ed; Zidong, Huang, Ed.

2001-01-01

These three issues contain the following articles written in Chinese: "On Conflated Theme in Systemic Functional Grammar" (Huang Guo-Wen); "A Cognitive Approach to the Conceptual Semantic Structures of Causation" (Cheng Qi-Long); "Falsifying the Internal Argument Hypothesis" (Zhao Yan-Chun); "Existential…

A note on the preconditioner Pm=(I+Sm)

NASA Astrophysics Data System (ADS)

Kohno, Toshiyuki; Niki, Hiroshi

2009-03-01

Kotakemori et al. [H. Kotakemori, K. Harada, M. Morimoto, H. Niki, A comparison theorem for the iterative method with the preconditioner (I+Smax), Journal of Computational and Applied Mathematics 145 (2002) 373-378] have reported that the convergence rate of the iterative method with a preconditioner Pm=(I+Sm) was superior to one of the modified Gauss-Seidel method under the condition. These authors derived a theorem comparing the Gauss-Seidel method with the proposed method. However, through application of a counter example, Wen Li [Wen Li, A note on the preconditioned GaussSeidel (GS) method for linear systems, Journal of Computational and Applied Mathematics 182 (2005) 81-91] pointed out that there exists a special matrix that does not satisfy this comparison theorem. In this note, we analyze the reason why such a to counter example may be produced, and propose a preconditioner to overcome this problem.

Empirical correlations for axial dispersion coefficient and Peclet number in fixed-bed columns.

PubMed

Rastegar, Seyed Omid; Gu, Tingyue

2017-03-24

In this work, a new correlation for the axial dispersion coefficient was obtained using experimental data in the literature for axial dispersion in fixed-bed columns packed with particles. The Chung and Wen correlation, the De Ligny correlation are two popular empirical correlations. However, the former lacks the molecular diffusion term and the latter does not consider bed voidage. The new axial dispersion coefficient correlation in this work was based on additional experimental data in the literature by considering both molecular diffusion and bed voidage. It is more comprehensive and accurate. The Peclet number correlation from the new axial dispersion coefficient correlation on the average leads to 12% lower Peclet number values compared to the values from the Chung and Wen correlation, and in many cases much smaller than those from the De Ligny correlation. Copyright © 2017 Elsevier B.V. All rights reserved.

Dissolved molybdenum and uranium in the Three Rivers of eastern Tibet

NASA Astrophysics Data System (ADS)

Noh, H.; Huh, Y.

2006-12-01

Three large rivers - the Chang Jiang (Yangtze), Mekong (Lancang Jiang) and Salween (Nu Jiang) - originate in eastern Tibet and run in close parallel over 300 km near the eastern Himalayan syntaxis. They flow across suture zones and faults generated by the collision of India and Eurasia. Sixty-five water samples were collected in summer of 1999 to 2004 and nine in winter of 2002 to 2003. The complex geologic makeup of the Three Rivers region (TRR) results in widely varying major and trace element compositions of the dissolved load. Two redox-sensitive elements, molybdenum (Mo) and uranium (U) were analyzed by ICP-MS, as potential proxies for weathering of sedimentary organic carbon and resultant generation of atmospheric carbon dioxide. Additionally, Mo constitutes an essential co-enzyme for biology. Mo concentration ranges from 0.76 to 21.3 nmol/kg (average: 6.24 nmol/kg, average of global rivers: ~5 nmol/kg (Martin and Meybeck, 1979)), and U concentration varies from 2.86 to 10.7 nmol/kg (average: 3.12 nmol/kg, average of global rivers: ~1 nmol/kg (Palmer and Edmond, 1993)). The highest values of Mo and U are observed in the headwater tributary sample of the Chang Jiang, where evaporite dissolution is dominant. Statistical analyses show that Mo is closely correlated with U (r = 0.713, p < 0.01) indicating similar source of Mo and U to river waters in the TRR. Inverse correlation with Si/total anions ratio suggests that their sources are non-silicate minerals. The correlation with sulfate supports the use Mo and U as proxies for weathering of reduced organic-rich sediments (Mo and SO4: r = 0.383, p < 0.01; U and SO4: r = 0.508, p < 0.01). Among the parameters tested (basin area, elevation, relief, slope, T, precipitation, potential-evapotranspiration, normalized difference vegetation index (NDVI), population density), best positive correlation (r>0.5) is shown between U and basin elevation, and negative correlation is shown between U and temperature, precipitation

Anti-Reflection Characteristics of Si Nanowires for Enhanced Photoluminescence from CdTe/CdS Quantum Dots

NASA Astrophysics Data System (ADS)

Wang, Hong-Yu; Shan, Dan; Xu, Ling

2018-05-01

Not Available Supported by the Qing Lan Project of the Higher Education Institutions of Jiangsu Province, Qing Lan Project of Yangzhou Polytechnic Institute, the Natural Science Foundation of Yangzhou City under Grant No YZ2016123, and the National Natural Science Foundation of China under Grant No 61376004.

Projective limits of state spaces II. Quantum formalism

NASA Astrophysics Data System (ADS)

Lanéry, Suzanne; Thiemann, Thomas

2017-06-01

In this series of papers, we investigate the projective framework initiated by Kijowski (1977) and Okołów (2009, 2014, 2013), which describes the states of a quantum theory as projective families of density matrices. A short reading guide to the series can be found in Lanéry (2016). After discussing the formalism at the classical level in a first paper (Lanéry, 2017), the present second paper is devoted to the quantum theory. In particular, we inspect in detail how such quantum projective state spaces relate to inductive limit Hilbert spaces and to infinite tensor product constructions (Lanéry, 2016, subsection 3.1) [1]. Regarding the quantization of classical projective structures into quantum ones, we extend the results by Okołów (2013), that were set up in the context of linear configuration spaces, to configuration spaces given by simply-connected Lie groups, and to holomorphic quantization of complex phase spaces (Lanéry, 2016, subsection 2.2) [1].

Publisher Correction: A Co3O4-CDots-C3N4 three component electrocatalyst design concept for efficient and tunable CO2 reduction to syngas.

PubMed

Guo, Sijie; Zhao, Siqi; Wu, Xiuqin; Li, Hao; Zhou, Yunjie; Zhu, Cheng; Yang, Nianjun; Jiang, Xin; Gao, Jin; Bai, Liang; Liu, Yang; Lifshitz, Yeshayahu; Lee, Shuit-Tong; Kang, Zhenhui

2018-02-08

The original HTML version of this Article omitted to list Yeshayahu Lifshitz as a corresponding author and incorrectly listed Shuit-Tong Lee as a corresponding author.Correspondingly, the original PDF version of this Article incorrectly stated that "Correspondence and requests for materials should be addressed to X.J. (email: xin.jiang@uni-siegen.de), or to Y.L. (email: yangl@suda.edu.cn), or to S.-T.L. (email: shayli@technion.ac.il), or to Z.K. (email: zhkang@suda.edu.cn)", instead of the correct "Correspondence and requests for materials should be addressed to X.J. (email: xin.jiang@uni-siegen.de), or to Y. Liu (email: yangl@suda.edu.cn), or to Y. Lifshitz (email: shayli@technion.ac.il), or to Z.K. (email: zhkang@suda.edu.cn)".This has now been corrected in the PDF and HTML versions of the Article.

The Business Education Lab and Local Area Networking for Curriculum Improvement.

ERIC Educational Resources Information Center

Seals, Georgina; And Others

This guide explains how to incorporate a local area network (LAN) into the business education curriculum. The first section defines LAN, a communications system that links computers and other peripherals within an office or throughout nearby buildings and shares multiuser software and send and/or receive information. Curriculum planning…

The 10 Hottest Technologies in Telecom.

ERIC Educational Resources Information Center

Flanagan, Patrick

1996-01-01

Synthesizes opinions of experts regarding technologies deemed most likely to enter the telecommunications mainstream by 1998, including: (1) the Java programming language; (2) voice- over frame relay; (3) virtual local area networks (LANs); (4) cable modems; (5) gigabit LANs; (6) Internet appliances; (7) personal satellite phones; (8) intranets;…

Identification of Metastatic Tumor Stem Cell

DTIC Science & Technology

2011-09-01

Aya Kobayashi, Bo Xia, Misako Watabe, Sudha K Pai, Shigeru Hirota, Fei Xing, Wen Liu, Puspa R Pandey, Koji Fukuda, Vishnu Modur, Arnab Ghosh, Andrew...Xing, Puspa R. Pandey, Koji Fukuda, Megumi Iiizumi, Kounosuke Watabe. Hyaluronan synthase 2 promotes tumor progression by stimulating interaction of

Honey Lake Geothermal Project, Lassen County, California

NASA Astrophysics Data System (ADS)

1984-11-01

The drilling, completion, and testing of deep well WEN-2 for a hybrid electric power project which will use the area's moderate temperature geothermal fluids and locally procured wood fuel is reported. The project is located within the Wendel-Amedee Known Geothermal Resource Area.

Space Flight Operations Center local area network

NASA Technical Reports Server (NTRS)

Goodman, Ross V.

1988-01-01

The existing Mission Control and Computer Center at JPL will be replaced by the Space Flight Operations Center (SFOC). One part of the SFOC is the LAN-based distribution system. The purpose of the LAN is to distribute the processed data among the various elements of the SFOC. The SFOC LAN will provide a robust subsystem that will support the Magellan launch configuration and future project adaptation. Its capabilities include (1) a proven cable medium as the backbone for the entire network; (2) hardware components that are reliable, varied, and follow OSI standards; (3) accurate and detailed documentation for fault isolation and future expansion; and (4) proven monitoring and maintenance tools.

Scalable Algorithms for Parallel Discrete Event Simulation Systems in Multicore Environments

DTIC Science & Technology

2013-05-01

consolidated at the sender side. At the receiver side, the messages are deconsolidated and delivered to the appropriate thread. This approach bears some...Jiang, S. Kini, W. Yu, D. Buntinas, P. Wyckoff, and D. Panda . Performance comparison of mpi implementations over infiniband, myrinet and quadrics

A Framework for Applying Asynchronous Transfer Mode (ATM) Technology to Command, Control and Communications Systems

DTIC Science & Technology

1994-06-01

available they can be implemented in ATM LANs by using different reserved signaling channels ( Biagioni , Cooper, and Sansom, 1993, p. 35). An argument...conference, San Francisco, California, 12-14 April 1994. Biagioni , E., Cooper, E. and Sansom, R., "Designing a Practical ATM LAN", IEEE Network, v. 7, March

Local Area Networks in Education: Overview, Applications, and Current Limitations.

ERIC Educational Resources Information Center

Piele, Philip K.

Local area networks (LAN) are privately owned communication systems that connect multivendor devices at high speed. As microcomputers become more common in schools, user interest in sharing information, software, and peripherals will increase. A basic understanding of the operation of all LAN's can be gained by knowing four elements: media,…

Mice exposed to dim light at night exaggerate inflammatory responses to lipopolysaccharide.

PubMed

Fonken, Laura K; Weil, Zachary M; Nelson, Randy J

2013-11-01

The mammalian circadian system regulates many physiological functions including inflammatory responses. Appropriately timed light information is essential for maintaining circadian organization. Over the past ∼120 years, urbanization and the widespread adoption of electric lights have dramatically altered lighting environments. Exposure to light at night (LAN) is pervasive in modern society and disrupts core circadian clock mechanisms. Because microglia are the resident macrophages in the brain and macrophages contain intrinsic circadian clocks, we hypothesized that chronic exposure to LAN would alter microglia cytokine expression and sickness behavior following LPS administration. Exposure to 4 weeks of dim LAN elevated inflammatory responses in mice. Mice exposed to dimly lit, as compared to dark, nights exaggerated changes in body temperature and elevated microglia pro-inflammatory cytokine expression following LPS administration. Furthermore, dLAN mice had a prolonged sickness response following the LPS challenge. Mice exposed to dark or dimly lit nights had comparable sickness behavior directly following the LPS injection; however, dLAN mice showed greater reductions in locomotor activity, increased anorectic behavior, and increased weight loss than mice maintained in dark nights 24h post-LPS injection. Overall, these data suggest that chronic exposure to even very low levels of light pollution may alter inflammatory responses. These results may have important implications for humans and other urban dwelling species that commonly experience nighttime light exposure. Copyright © 2013 Elsevier Inc. All rights reserved.

Localized Multiple Kernel Learning A Convex Approach

DTIC Science & Technology

2016-11-22

data. All the aforementioned approaches to localized MKL are formulated in terms of non-convex optimization problems, and deep the- oretical...learning. IEEE Transactions on Neural Networks, 22(3):433–446, 2011. Jingjing Yang, Yuanning Li, Yonghong Tian, Lingyu Duan, and Wen Gao. Group-sensitive

ICCE/ICCAI 2000 Full & Short Papers (Computer-Assisted Language Learning).

ERIC Educational Resources Information Center

2000

This document contains the following full and short papers on computer-assisted language learning (CALL) from ICCE/ICCAI 2000 (International Conference on Computers in Education/International Conference on Computer-Assisted Instruction): (1) "A Computer-Assisted English Abstract Words Learning Environment on the Web" (Wenli Tsou and…

Interoceanic variation in the rare earth, major, and trace element depositional chemistry of chert: Perspectives gained from the DSDP and ODP record

USGS Publications Warehouse

Murray, R.W.; Buchholtz ten Brink, Marilyn R.; Gerlach, David C.; Russ III, G. Price; Jones, David L.

1992-01-01

Rare earth element (REE), major, and trace element abundances and relative fractionations in forty nodular cherts sampled by the Deep Sea Drilling Project (DSDP) and Ocean Drilling Program (ODP) indicate that the REE composition of chert records the interplay between terrigenous sources and scavenging from the local seawater. Major and (non-REE) trace element ratios indicate that the aluminosilicate fraction within the chert is similar to NASC (North American Shale Composite), with average Pacific chert including ~7% NASC-like particles, Indian chert ~ 11% NASC, Atlantic chert ~ 17% NASC, and southern high latitude (SHL) chert 53% NASC. Using La as a proxy for ∑REE, approximations of Laex (the amount of La in excess of that supplied by the detrital aluminosilicate fraction) indicate that Pacific chert contains the greatest Laex (85% of Latotal) and SHL chert the least (38% of Latotal). As shown by interelement associations, this Laex is most likely an adsorbed component onto aluminosilicate and phosphatic phases.Accordingly, chert from the large Pacific Ocean, where deposition occurs relatively removed from significant terrigenous input, records a depositional REE signal dominated by adsorption of dissolved REEs from seawater. Pacific chert CeCe*⪡ 1 and LanYbn ~ 0.8-1, resulting from adsorption of local Ce-depleted seawater and preferential adsorption of LREEs from seawater (e.g., LanYbn ~ 0.4), which increases the LanYbn ratio recorded in chert. Chert from the Atlantic basin, a moderately sized ocean basin lined by passive margins and with more terrigenous input than the Pacific, records a mix of adsorptive and terrigenous REE signals, with moderately negative Ce anomalies and LanYbn">LanYbn ratios intermediate to those of the Pacific and those of terrigenous input. Chert from the SHL region is dominated by the large terrigenous input on the Antarctic passive margin, with inherited CeCe*~1">CeCe*~1 and inherited LanYbn">LanYbn values of ~1.2–1

Somatostatin receptor PET in neuroendocrine tumours: 68Ga-DOTA0,Tyr3-octreotide versus 68Ga-DOTA0-lanreotide.

PubMed

Putzer, Daniel; Kroiss, Alexander; Waitz, Dietmar; Gabriel, Michael; Traub-Weidinger, Tatjana; Uprimny, Christian; von Guggenberg, Elisabeth; Decristoforo, Clemens; Warwitz, Boris; Widmann, Gerlig; Virgolini, Irene Johanna

2013-02-01

The aim of this study was to evaluate the impact of (68)Ga-labelled DOTA(0)-lanreotide ((68)Ga-DOTA-LAN) on the diagnostic assessment of neuroendocrine tumour (NET) patients with low to moderate uptake on planar somatostatin receptor (SSTR) scintigraphy or (68)Ga-labelled DOTA(0),Tyr(3)-octreotide ((68)Ga-DOTA-TOC) positron emission tomography (PET). Fifty-three patients with histologically confirmed NET and clinical signs of progressive disease, who had not qualified for peptide receptor radionuclide therapy (PRRT) on planar SSTR scintigraphy or (68)Ga-DOTA-TOC PET (n = 38) due to lack of tracer uptake, underwent (68)Ga-DOTA-LAN PET to evaluate a treatment option with (90)Y-labelled lanreotide according to the MAURITIUS trial. The included patients received 150 ± 30 MBq of each radiopharmaceutical intravenously. PET scans were acquired 60-90 min after intravenous bolus injection. Image results from both PET scans were compared head to head, focusing on the intensity of tracer uptake in terms of treatment decision. CT was used for morphologic correlation of tumour lesions. To further evaluate the binding affinities of each tracer, quantitative and qualitative values were calculated for target lesions. (68)Ga-DOTA-LAN and (68)Ga-DOTA-TOC both showed equivalent findings in 24/38 patients when fused PET/CT images were interpreted. The sensitivity, specificity and accuracy of (68)Ga-DOTA-LAN in comparison to CT were 0.63, 0.5 and 0.62 (n = 53; p < 0.0001) and for (68)Ga-DOTA-TOC in comparison to CT 0.78, 0.5 and 0.76 (n = 38; p < 0.013), respectively. (68)Ga-DOTA-TOC showed a significantly higher maximum standardized uptake value (SUV(max)) regarding the primary tumour in 25 patients (p < 0.003) and regarding the liver in 30 patients (p < 0.009) compared to (68)Ga-DOTA-LAN. Corresponding values of both PET scans for tumour and liver did not show any significant correlation. (68)Ga-DOTA-TOC revealed more tumour sites than (68)Ga-DOTA-LAN

Parameter identification of piezoelectric hysteresis model based on improved artificial bee colony algorithm

NASA Astrophysics Data System (ADS)

Wang, Geng; Zhou, Kexin; Zhang, Yeming

2018-04-01

The widely used Bouc-Wen hysteresis model can be utilized to accurately simulate the voltage-displacement curves of piezoelectric actuators. In order to identify the unknown parameters of the Bouc-Wen model, an improved artificial bee colony (IABC) algorithm is proposed in this paper. A guiding strategy for searching the current optimal position of the food source is proposed in the method, which can help balance the local search ability and global exploitation capability. And the formula for the scout bees to search for the food source is modified to increase the convergence speed. Some experiments were conducted to verify the effectiveness of the IABC algorithm. The results show that the identified hysteresis model agreed well with the actual actuator response. Moreover, the identification results were compared with the standard particle swarm optimization (PSO) method, and it can be seen that the search performance in convergence rate of the IABC algorithm is better than that of the standard PSO method.

Retrieval of mass and sizes of particles in sandstorms using two MODIS IR bands: A case study of April 7, 2001 sandstorm in China

NASA Astrophysics Data System (ADS)

Gu, Yingxin; Rose, William I.; Bluth, Gregg J. S.

2003-08-01

A thermal infrared remote sensing retrieval method developed by Wen and Rose [1994], which retrieves particle sizes, optical depth, and total masses of silicate particles in the volcanic cloud, was applied to an April 07, 2001 sandstorm over northern China, using MODIS. Results indicate that the area of the dust cloud observed was 1.34 million km2, the mean particle radius of the dust was 1.44 μm, and the mean optical depth at 11 μm was 0.79. The mean burden of dust was approximately 4.8 tons/km2 and the main portion of the dust storm on April 07, 2001 contained 6.5 million tons of dust. The results are supported by both independent remote sensing data (TOMS) and in situ data for a similar event in 1998. This paper demonstrates that Wen and Rose's retrieval method could be successfully applied to past and future sandstorm events using IR channels of AVHRR, GOES or MODIS.

The Lexical Breadth of Undergraduate Novice Level Writing Competency

ERIC Educational Resources Information Center

Douglas, Scott Roy

2013-01-01

This study builds on previous work exploring reading and listening lexical thresholds (Nation, 2006; Laufer & Ravenhorst-Kalovski, 2010; Schmitt, Jiang, & Grabe, 2011) in order to investigate productive vocabulary targets that mark successful entry-level undergraduate writing. Papers that passed the Effective Writing Test (EWT) were chosen…

Islands and Bridges: Making Sense of Marked Nodes in Large Graphs

DTIC Science & Technology

2012-08-01

time-evolving graphs. References [1] Nouf M. Kh. Alsudairy, Vijay V. Raghavan, Alaaeldin M. Hafez, and Hassan I Mathkour. Connection subgraphs: A survey...Riedy, David A. Bader, Karl Jiang, Pushkar Pande, , and Richa Sharma . Detecting communities from given seeds in social networks. Technical Report GT-CSE

Light at night activates IGF-1R/PDK1 signaling and accelerates tumor growth in human breast cancer xenografts.

PubMed

Wu, Jinghai; Dauchy, Robert T; Tirrell, Paul C; Wu, Steven S; Lynch, Darin T; Jitawatanarat, Potjana; Burrington, Christine M; Dauchy, Erin M; Blask, David E; Greene, Michael W

2011-04-01

Regulation of diurnal and circadian rhythms and cell proliferation are coupled in all mammals, including humans. However, the molecular mechanisms by which diurnal and circadian rhythms regulate cell proliferation are relatively poorly understood. In this study, we report that tumor growth in nude rats bearing human steroid receptor-negative MCF-7 breast tumors can be significantly accelerated by exposing the rats to light at night (LAN). Under normal conditions of an alternating light/dark cycle, proliferating cell nuclear antigen (PCNA) levels in tumors were maximal in the early light phase but remained at very low levels throughout the daily 24-hour cycle period monitored. Surprisingly, PCNA was expressed in tumors continually at a high level throughout the entire 24-hour period in LAN-exposed nude rats. Daily fluctuations of Akt and mitogen activated protein kinase activation in tumors were also disrupted by LAN. These fluctuations did not track with PCNA changes, but we found that activation of the Akt stimulatory kinase phosphoinositide-dependent protein kinase 1 (PDK1) directly correlated with PCNA levels. Expression of insulin-like growth factor 1 receptor (IGF-1R), an upstream signaling molecule for PDK1, also correlated with fluctuations of PDK1/PCNA in the LAN group. In addition, circulating IGF-1 concentrations were elevated in LAN-exposed tumor-bearing nude rats. Finally, RNAi-mediated knockdown of PDK1 led to a reduction in PCNA expression and cell proliferation in vitro and tumor growth in vivo, indicating that PDK1 regulates breast cancer growth in a manner correlated with PCNA expression. Taken together, our findings demonstrate that LAN exposure can accelerate tumor growth in vivo, in part through continuous activation of IGF-1R/PDK1 signaling.

High Speed Computing, LANs, and WAMs

NASA Technical Reports Server (NTRS)

Bergman, Larry A.; Monacos, Steve

1994-01-01

Optical fiber networks may one day offer potential capacities exceeding 10 terabits/sec. This paper describes present gigabit network techniques for distributed computing as illustrated by the CASA gigabit testbed, and then explores future all-optic network architectures that offer increased capacity, more optimized level of service for a given application, high fault tolerance, and dynamic reconfigurability.

Large Signal Time Dependent Quantum Mechanical Transport in Quantum Phase Based Devices

DTIC Science & Technology

1994-06-10

tansport ths spatial dependence suggests equilibrium electron temperature values that difer fr•m the ambient. The prospect of quantum heMing and cooling...the factor 21 is a consequence of the defintion of the nionlocal coordinate (wen eqn (7)]. In this transformation it APPENDIX C is asserted that the

Using ZWDOS to Communicate in Chinese on PC.

ERIC Educational Resources Information Center

Xie, Tianwei

1995-01-01

Describes the availability, installation, and use of the ZhonWen Disk Operating System (ZWDOS) to display, print, and transmit Chinese characters on conventional International Business Machines (IBM) personal computers and IBM-compatible machines. Also discussed is the use of ZWDOS to compose electronic mail messages, read newsgroups, and access…

China Report, Economic Affairs

DTIC Science & Technology

1986-04-11

struggle against serious economic crime. Vice Chairmen of the provincial People’s Congress Standing Committee Chen Anyu, Shang Jingcai, Li Yuhua , Wu...Jingji, Wu Ruoan, Tan Jiazhen, Shu Wen, Cao Tianqin, and Zuo Zhaoji, vice mayors of Shanghai; and leading members of the Shanghai Higher People’s

Human and Social Capital in China's Learning Villages

ERIC Educational Resources Information Center

Huang, Yan; Boshier, Roger

2008-01-01

In March 2006, Premier Wen Jiabao acknowledged that the situation in the Chinese countryside is desperate and claimed new resources would be devoted to healthcare and education. This announcement should have pleased architects of the Chinese "learning initiative" who are building learning cities and villages. The authors describe why…

Variations in Cognitive Maps: Understanding Individual Differences in Navigation

ERIC Educational Resources Information Center

Weisberg, Steven M.; Schinazi, Victor R.; Newcombe, Nora S.; Shipley, Thomas F.; Epstein, Russell A.

2014-01-01

There are marked individual differences in the formation of cognitive maps both in the real world and in virtual environments (VE; e.g., Blajenkova, Motes, & Kozhevnikov, 2005; Chai & Jacobs, 2010; Ishikawa & Montello, 2006; Wen, Ishikawa, & Sato, 2011). These differences, however, are poorly understood and can be difficult to…

System analysis for the Huntsville Operation Support Center distributed computer system

NASA Technical Reports Server (NTRS)

Ingels, F. M.

1986-01-01

A simulation model of the NASA Huntsville Operational Support Center (HOSC) was developed. This simulation model emulates the HYPERchannel Local Area Network (LAN) that ties together the various computers of HOSC. The HOSC system is a large installation of mainframe computers such as the Perkin Elmer 3200 series and the Dec VAX series. A series of six simulation exercises of the HOSC model is described using data sets provided by NASA. The analytical analysis of the ETHERNET LAN and the video terminals (VTs) distribution system are presented. An interface analysis of the smart terminal network model which allows the data flow requirements due to VTs on the ETHERNET LAN to be estimated, is presented.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Intrator, Miranda Huang

Los Alamos National Security, LLC (LANS) is the manager and operator of Los Alamos National Laboratory (Los Alamos) for the U.S. Department of Energy National Nuclear Security Administration under contract DE-AC52- 06NA25396. Los Alamos is a mission-centric Federally Funded Research and Development Center focused on solving critical national security challenges through science and engineering for both government and private customers. LANS is opening this formal Request for Information (RFI) to gauge interest in engaging as an industry partner to LANS for collaboration in advancing the bio-assessment platform described below. Please see last section for details on submitting a Letter ofmore » Interest.« less

Numerical Simulations of Homogeneous Turbulence Using Lagrangian-Averaged Navier-Stokes Equations

NASA Technical Reports Server (NTRS)

Mohseni, Kamran; Shkoller, Steve; Kosovic, Branko; Marsden, Jerrold E.; Carati, Daniele; Wray, Alan; Rogallo, Robert

2000-01-01

The Lagrangian-averaged Navier-Stokes (LANS) equations are numerically evaluated as a turbulence closure. They are derived from a novel Lagrangian averaging procedure on the space of all volume-preserving maps and can be viewed as a numerical algorithm which removes the energy content from the small scales (smaller than some a priori fixed spatial scale alpha) using a dispersive rather than dissipative mechanism, thus maintaining the crucial features of the large scale flow. We examine the modeling capabilities of the LANS equations for decaying homogeneous turbulence, ascertain their ability to track the energy spectrum of fully resolved direct numerical simulations (DNS), compare the relative energy decay rates, and compare LANS with well-accepted large eddy simulation (LES) models.

Local Area Network: Community Involvement, Social Capital, and Glocalization at NetU

ERIC Educational Resources Information Center

Trevett-Smith, Matthew D.

2010-01-01

Ethnographic and interview data from a long-term study of "NetU," a wired community and college, are used to investigate the effects of computer-mediated communication on social relationships. During the course of this research "LAN" residents of NetU are compared with a similar group of non-LAN residents who lived in the same neighborhood, but…

Networking CD-ROMs: The Decision Maker's Guide to Local Area Network Solutions.

ERIC Educational Resources Information Center

Elshami, Ahmed M.

In an era when patrons want access to CD-ROM resources but few libraries can afford to buy multiple copies, CD-ROM local area networks (LANs) are emerging as a cost-effective way to provide shared access. To help librarians make informed decisions, this manual offers information on: (1) the basics of LANs, a "local area network primer";…

Contextual Cueing in Multiconjunction Visual Search Is Dependent on Color- and Configuration-Based Intertrial Contingencies

ERIC Educational Resources Information Center

Geyer, Thomas; Shi, Zhuanghua; Muller, Hermann J.

2010-01-01

Three experiments examined memory-based guidance of visual search using a modified version of the contextual-cueing paradigm (Jiang & Chun, 2001). The target, if present, was a conjunction of color and orientation, with target (and distractor) features randomly varying across trials (multiconjunction search). Under these conditions, reaction times…

76 FR 12325 - Small Diameter Graphite Electrodes From the People's Republic of China: Preliminary Results of...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-07

... Group). 26 Haimen Shuguang Carbon Industry Co., Ltd. 27 Handan Hanbo Material Co., Ltd. 28 Hebei Long Great Wall Electrode Co., Ltd. (aka Chang Cheng Chang Electrode Co., Ltd. and Laishui Long Great Wall... Inner Mongolia Xinghe County Hongyuan Electrical Carbon Factory. 35 Jiang Long Carbon. 36 Jiangsu Yafei...

Islands and Bridges: Making Sense of Marked Nodes in Large Graphs

DTIC Science & Technology

2013-01-01

our methods to heterogeneous and time-evolving graphs. References [1] Nouf M. Kh. Alsudairy, Vijay V. Raghavan, Alaaeldin M. Hafez, and Hassan I...multi-relational graphs. SIGKDD Explor., 7(2):56–63, 2005. [24] Jason Riedy, David A. Bader, Karl Jiang, Pushkar Pande, , and Richa Sharma . Detecting

The Attentional Boost Effect with Verbal Materials

ERIC Educational Resources Information Center

Mulligan, Neil W.; Spataro, Pietro; Picklesimer, Milton

2014-01-01

Study stimuli presented at the same time as unrelated targets in a detection task are better remembered than stimuli presented with distractors. This attentional boost effect (ABE) has been found with pictorial (Swallow & Jiang, 2010) and more recently verbal materials (Spataro, Mulligan, & Rossi-Arnaud, 2013). The present experiments…

Material for "Substrate temperature controls molecular orientation in two-component vapor- deposited glasses." Soft Matter, 2016, 12, 3265.

DOE Data Explorer

Jiang, Jing [Nanjing University; Walters, Diane M [University of Wisconsin-Madison; Zhou, Dongshan [Nanjing University; Ediger, Mark D [University of Wisconsin-Madison

2016-08-18

Data set for work presented in Jiang, J.; Walters, D. M.; Zhou, D.; Ediger, M. D. “Substrate Temperature Controls Molecular Orientation in Two -Component Vapor-deposited Glasses.” Soft Matt. 2016, 12, 3265. Includes all data presented in the manuscript as well as example raw data and analysis.

AMULET: A MUlti-cLuE Approach to Image Forensics

DTIC Science & Technology

2014-12-31

celebrities have been substituted in the other two pictures. 3.2.5 Choice of reliability properties Let us now apply the BBA mapping approach proposed in...Jiang, and L. Ma, “Ds evidence theory based digital image trustworthiness evaluation model,” in MINES 2009, International Conference on Multimedia

Electronic and mechanical properties of 5d transition metal mononitrides via first principles

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhao Erjun; Graduate School, Chinese Academy of Sciences, Beijing 100049; Wu Zhijian

2008-10-15

The electronic and mechanical properties of 5d transition metal mononitrides from LaN to AuN are systematically investigated by use of the density-functional theory. For each nitride, six structures are considered, i.e., rocksalt, zinc blende, CsCl, wurtzite, NiAs and WC structures. Among the considered structures, rocksalt structure is the most stable for LaN, HfN and AuN, WC structure for TaN, NiAs structure for WN, wurtzite structure for ReN, OsN, IrN and PtN. The most stable structure for each nitride is mechanically stable. The formation enthalpy increases from LaN to AuN. For LaN, HfN and TaN, the formation enthalpy is negative formore » all the considered structures, while from WN to AuN, except wurtzite structure in ReN, the formation enthalpy is positive. The calculated density of states shows that they are all metallic. ReN in NiAs structure has the largest bulk modulus, 418 GPa. The largest shear modulus 261 GPa is from TaN in WC structure. Trends are discussed. - Graphical abstract: Formation enthalpy per formula unit {delta}H (eV) for all the considered structures of 5d transition metal mononitrides MN (M=La-Au). It was shown that the formation enthalpy increases from LaN to AuN. The nitrides with negative values indicate that they can be synthesized experimentally at ambient conditions.« less

TU-E-TOUR-I-00: Exhibit Hall Guided Tours-Dosimters for QC in Diagnostic Imaging (Tuesday)

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

Tour Leader: Xia Jiang, Ohio State University, Columbus, OH Tour Guides: Xia Jiang, Ohio State University, Columbus, OH Kevin Little, The University of Chicago, Chicago, IL Christina Sammet, Lurie Children’s Hospital of Chicago, Chicago, IL Participating Vendors: IBA PTW - New York Radcal Corporation RTI Electronics, Inc. Exhibit Hall Guided Tours is a new program launching this year at the Annual Meeting. The Guided Tours are designed to enhance the interaction between meeting attendees and exhibitors. This year’s Imaging Guided Tours are organized around the theme of dosimeters for quality control in diagnostic imaging. Tours will begin with an introductionmore » and background given by Dr. Xia Jiang, the Tour Leader. The introduction will cover the types and properties of different radiation dosimeters used for quality assurance in clinical radiology. Attendees will then break into smaller groups, each lead by an AAPM-member Tour Guide. The tour groups will visit the exhibit booths of vendors who provide appropriate dosimeters, and a vendor representative will give a presentation to the group about their particular product(s). The vendor representatives as well as the Tour Guides will be available to answer questions. Outline: Types and properties of radiation detectors and dosimeters Ionization chamber dosimeters Solid state dosimeters Dosimeter calibration: Primary and secondary standards dosimetry laboratories Instruments for measuring tube voltage and exposure time Vendor presentations will likely cover features and innovations of different dosimeter systems, as well as their practical use. Learning Objectives: Understand the types and properties of different instrumentations used for quality control in diagnostic imaging. Understand the process of dosimeter calibration. Gain familiarity with the latest commercial dosimeter systems from different vendors.« less

WE-C-TOUR-I-00: Exhibit Hall Guided Tours-Dosimters for QC in Diagnostic Imaging (Wednesday)

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

Tour Leader: Xia Jiang, Ohio State University, Columbus, OH Tour Guides: Xia Jiang, Ohio State University, Columbus, OH Kevin Little, The University of Chicago, Chicago, IL Adrien Sanchez, University of Chicago, Chicago, IL Participating Vendors: IBA PTW - New York Radcal Corporation RTI Electronics, Inc. Exhibit Hall Guided Tours is a new program launching this year at the Annual Meeting. The Guided Tours are designed to enhance the interaction between meeting attendees and exhibitors. This year’s Imaging Guided Tours are organized around the theme of dosimeters for quality control in diagnostic imaging. Tours will begin with an introduction and backgroundmore » given by Dr. Xia Jiang, the Tour Leader. The introduction will cover the types and properties of different radiation dosimeters used for quality assurance in clinical radiology. Attendees will then break into smaller groups, each lead by an AAPM-member Tour Guide. The tour groups will visit the exhibit booths of vendors who provide appropriate dosimeters, and a vendor representative will give a presentation to the group about their particular product(s). The vendor representatives as well as the Tour Guides will be available to answer questions. Outline: Types and properties of radiation detectors and dosimeters Ionization chamber dosimeters Solid state dosimeters Dosimeter calibration: Primary and secondary standards dosimetry laboratories Instruments for measuring tube voltage and exposure time Vendor presentations will likely cover features and innovations of different dosimeter systems, as well as their practical use. Learning Objectives: Understand the types and properties of different instrumentations used for quality control in diagnostic imaging. Understand the process of dosimeter calibration. Gain familiarity with the latest commercial dosimeter systems from different vendors.« less

WE-C-TOUR-I-01: Dosimters for QC in Diagnostic Imaging

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jiang, X.

Tour Leader: Xia Jiang, Ohio State University, Columbus, OH Tour Guides: Xia Jiang, Ohio State University, Columbus, OH Kevin Little, The University of Chicago, Chicago, IL Adrien Sanchez, University of Chicago, Chicago, IL Participating Vendors: IBA PTW - New York Radcal Corporation RTI Electronics, Inc. Exhibit Hall Guided Tours is a new program launching this year at the Annual Meeting. The Guided Tours are designed to enhance the interaction between meeting attendees and exhibitors. This year’s Imaging Guided Tours are organized around the theme of dosimeters for quality control in diagnostic imaging. Tours will begin with an introduction and backgroundmore » given by Dr. Xia Jiang, the Tour Leader. The introduction will cover the types and properties of different radiation dosimeters used for quality assurance in clinical radiology. Attendees will then break into smaller groups, each lead by an AAPM-member Tour Guide. The tour groups will visit the exhibit booths of vendors who provide appropriate dosimeters, and a vendor representative will give a presentation to the group about their particular product(s). The vendor representatives as well as the Tour Guides will be available to answer questions. Outline: Types and properties of radiation detectors and dosimeters Ionization chamber dosimeters Solid state dosimeters Dosimeter calibration: Primary and secondary standards dosimetry laboratories Instruments for measuring tube voltage and exposure time Vendor presentations will likely cover features and innovations of different dosimeter systems, as well as their practical use. Learning Objectives: Understand the types and properties of different instrumentations used for quality control in diagnostic imaging. Understand the process of dosimeter calibration. Gain familiarity with the latest commercial dosimeter systems from different vendors.« less

Edge-entanglement spectrum correspondence in a nonchiral topological phase and Kramers-Wannier duality

NASA Astrophysics Data System (ADS)

Ho, Wen Wei; Cincio, Lukasz; Moradi, Heidar; Gaiotto, Davide; Vidal, Guifre

2015-03-01

In a system with chiral topological order, there is a remarkable correspondence between the edge and entanglement spectra: the low-energy spectrum of the system in the presence of a physical edge coincides with the lowest part of the entanglement spectrum (ES) across a virtual cut of the system into two parts, up to rescaling and shifting. This correspondence is believed to be due to the existence of protected gapless edge modes. In this paper, we explore whether the edge-entanglement spectrum correspondence extends to nonchiral topological phases, where there are no protected gapless edge modes. Specifically, we consider the Wen-plaquette model, which is equivalent to the Kitaev toric code model and has Z2 topological order (quantum double of Z2) . The unperturbed Wen-plaquette model displays an exact correspondence: both the edge and entanglement spectra within each topological sector a (a =1 ,⋯,4 ) are flat and equally degenerate. Here, we show, through a detailed microscopic calculation, that in the presence of generic local perturbations: (i) the effective degrees of freedom for both the physical edge and the entanglement cut consist of a (spin-1 /2 ) spin chain, with effective Hamiltonians Hedgea and Henta, respectively, both of which have a Z2 symmetry enforced by the bulk topological order; (ii) there is in general no match between the low-energy spectra of Hedgea and Henta, that is, there is no edge-ES correspondence. However, if supplement the Z2 topological order with a global symmetry (translational invariance along the edge/entanglement cut), i.e., by considering the Wen-plaquette model as a symmetry-enriched topological phase (SET), then there is a finite domain in Hamiltonian space in which both Hedgea and Henta realize the critical Ising model, whose low-energy effective theory is the c =1 /2 Ising CFT. This is achieved because the presence of the global symmetry implies that the effective degrees of freedom of both the edge and entanglement

Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (85th, Miami, Florida, August 5-8, 2002). International Communication Division.

ERIC Educational Resources Information Center

2002

The International Communication Division of the proceedings contains the following 18 papers: "Spy or Scapegoat: A News Framing Study of the 'New York Times'' Coverage of the Wen Ho Lee Case" (Jia Lin & Junhao Hong); "Individual Perceptions of International Correspondents in the Middle East: An Obstacle to Fair News?" (Dina…

Readers Response Approach to English Poetry Teaching.

ERIC Educational Resources Information Center

Lin, Antonia Hsiu-Chen; Sher, Teresa Hsiang-Jen

This paper describes an elective course at Taiwan's Wen Tzao Ursuline College of Modern Languages, "Concise English Poetry Appreciation and Recitation." The course is based on the reader response approach and targets third year students, leading them into the world of poetry through various stages (traditional nursery rhymes and simple,…

Implicit Learning of Local Context in Autism Spectrum Disorder

ERIC Educational Resources Information Center

Kourkoulou, Anastasia; Leekam, Susan R.; Findlay, John M.

2012-01-01

Although previous research has reported impairments in implicit learning in individuals with ASD, research using one implicit learning paradigm, the contextual cueing task (Chun and Jiang in Cognitive Psychol 36:28-71, 1998), shows evidence of intact ability to integrate spatial contextual information. Using an adaptation of this paradigm, we…

A Putative Gene sbe3-rs for Resistant Starch Mutated from SBE3 for Starch Branching Enzyme in Rice (Oryza sativa L.)

USDA-ARS?s Scientific Manuscript database

Foods high in resistant starch (RS) are beneficial to prevent various diseases including diabetes, colon cancer, diarrhea and chronic renal or hepatic diseases. Elevated RS in rice is important for public health since rice is a staple food for half of the world’s population. A japonica mutant ‘Jiang...

Spreading Our Wings: International Education as Journeys of Enriched Learning

ERIC Educational Resources Information Center

Foster, Karen K.; Yao, Yuankun; Buchanan-Butterfield, Dawna Lisa; Powell-Brown, Ann

2013-01-01

In the 21st century, the impact of globalization has increased the importance of the internationalization of education (Jiang, 2010; Lam, 2010). Because it is imperative for the success of their graduates, colleges are encouraged to offer international educational experiences to gain a competitive edge over other institutions of higher learning…

Energy Systems Integration News | Energy Systems Integration Facility |

Science.gov Websites

school. Andreas Schmitt spent hours this summer estimating grid voltage-under conditions when minimal Jiang of the State Grid Energy Research Institute in Beijing, China, to produce a review article that . The article, "Grid-Level Application of Electrical Energy Storage: Example Use Cases in the

L2 Chinese: Grammatical Development and Processing

ERIC Educational Resources Information Center

Mai, Ziyin

2016-01-01

Two recent books (Jiang, 2014, "Advances in Chinese as a second language"; Wang, 2013, "Grammatical development of Chinese among non-native speakers") provide new resources for exploring the role of processing in acquiring Chinese as a second language (L2). This review article summarizes, assesses and compares some of the…

Computer program for calculating aerodynamic characteristics of upper-surface-blowing and over-wing-blowing configurations

NASA Technical Reports Server (NTRS)

Lan, C. E.; Fillman, G. L.; Fox, C. H., Jr.

1977-01-01

The program is based on the inviscid wing-jet interaction theory of Lan and Campbell, and the jet entrainment theory of Lan. In the interaction theory, the flow perturbations are computed both inside and outside the jet, separately, and then matched on the jet surface to satisfy the jet boundary conditions. The jet Mach number is allowed to be different from the free stream value (Mach number nonuniformity). These jet boundary conditions require that the static pressure be continuous across the jet surface which must always remain as a stream surface. These conditions, as well as the wing-surface tangency condition, are satisified only in the linearized sense. The detailed formulation of these boundary conditions is based on the quasi-vortex-lattice method of Lan.

China’s Technology Sector

DTIC Science & Technology

2008-09-01

Technology Park ...................................................................................... 25 National Program 2006–2020 for the Development of...China’s Technology Sector 3 program of developing coorbital ASAT interceptors using microsatellites...D funding has proceeded according to Premier Wen Jiabao’s 15-year S&T plan, the National Program 2006–2020 for the Development of Science and

Determining Asset Criticality for Cyber Defense

DTIC Science & Technology

2011-09-23

sciences area that may be applied to our situation. In particular, Analytic Hierarchy Process ( AHP ) [20] and Hierarchical TOPSIS [21] [22] are some examples...34 Mathematical and Computer Modeling, vol. 45, no. 7-8, pp. 801-813, 2007. 33 [22] Jia-Wen Wang, Ching-Hsue Cheng, and Kun-Cheng Huang, " Fuzzy

Fascicle Nutrient and Biomass Responses of Young Loblolly Pine to Control of Woody and Herbaceous Competitors

Treesearch

Bruce R. Zutter; James H. Miller; H.L. Allen; S.M. Xedaker; M.B. Edwards; R.A. Newbold

1999-01-01

Individual fascicle mass and foliar nutrient content and concentration of young loblolly pine (Pinus taeda L.) wen evaluated on 13 locations of a regionwide competition study in the southeastern United States. The study included a factorial combination of two levels of weed control txatmalt (none, treated) and two levels of woody treatment (none,...

Assessing Model Fit: Caveats and Recommendations for Confirmatory Factor Analysis and Exploratory Structural Equation Modeling

ERIC Educational Resources Information Center

Perry, John L.; Nicholls, Adam R.; Clough, Peter J.; Crust, Lee

2015-01-01

Despite the limitations of overgeneralizing cutoff values for confirmatory factor analysis (CFA; e.g., Marsh, Hau, & Wen, 2004), they are still often employed as golden rules for assessing factorial validity in sport and exercise psychology. The purpose of this study was to investigate the appropriateness of using the CFA approach with these…

A Framework for Interaction and Cognitive Engagement in Connectivist Learning Contexts

ERIC Educational Resources Information Center

Wang, Zhijun; Chen, Li; Anderson, Terry

2014-01-01

Interaction has always been highly valued in education, especially in distance education (Moore, 1989; Anderson, 2003; Chen, 2004a; Woo & Reeves, 2007; Wang, 2013; Conrad, in press). It has been associated with motivation (Mahle, 2011; Wen-chi, et al., 2011), persistence (Tello, 2007; Joo, Lim, & Kim, 2011), deep learning (Offir, et al.,…

Wireless local area networking for linking a PC reporting system and PACS: clinical feasibility in emergency reporting.

PubMed

Yoshihiro, Akiko; Nakata, Norio; Harada, Junta; Tada, Shimpei

2002-01-01

Although local area networks (LANs) are commonplace in hospital-based radiology departments today, wireless LANs are still relatively unknown and untried. A linked wireless reporting system was developed to improve work throughput and efficiency. It allows radiologists, physicians, and technologists to review current radiology reports and images and instantly compare them with reports and images from previous examinations. This reporting system also facilitates creation of teaching files quickly, easily, and accurately. It consists of a Digital Imaging and Communications in Medicine 3.0-based picture archiving and communication system (PACS), a diagnostic report server, and portable laptop computers. The PACS interfaces with magnetic resonance imagers, computed tomographic scanners, and computed radiography equipment. The same kind of functionality is achievable with a wireless LAN as with a wired LAN, with comparable bandwidth but with less cabling infrastructure required. This wireless system is presently incorporated into the operations of the emergency and radiology departments, with future plans calling for applications in operating rooms, outpatient departments, all hospital wards, and intensive care units. No major problems have been encountered with the system, which is in constant use and appears to be quite successful. Copyright RSNA, 2002

Lansoprazole induces sensitivity to suboptimal doses of paclitaxel in human melanoma.

PubMed

Azzarito, Tommaso; Venturi, Giulietta; Cesolini, Albino; Fais, Stefano

2015-01-28

Tumor acidity is now considered an important determinant of drug-resistance and tumor progression, and anti-acidic approaches, such as Proton Pump inhibitors (PPIs), have demonstrated promising antitumor and chemo-sensitizing efficacy. The main purpose of the present study was to evaluate the possible PPI-induced sensitization of human melanoma cells to Paclitaxel (PTX). Our results show that PTX and the PPI Lansoprazole (LAN) combination was extremely efficient against metastatic melanoma cells, as compared to the single treatments, both in vitro and in vivo. We also showed that acidity plays an important role on the anti-tumor activity of these drugs, being detrimental for PTX activity, while crucial for the synergistic effect of PTX following pretreatment with LAN, due to its nature of pro-drug needing protonation for a full activation. We obtained straightforward results in a human melanoma xenograft model combining well tolerated LAN doses with suboptimal and poorly toxic doses of PTX. With this study we provide a clear evidence that the PPI LAN may be included in new combined therapy of human melanoma together with low doses of PTX. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

Potential Role of CD68 in Breast Cancer Bone Metastasis

DTIC Science & Technology

2013-01-01

research 2006, 131(2):267-275. 32. Hanavadi S, Martin TA, Watkins G, Mansel RE, Jiang WG: Expression of interleukin 11 and its receptor and their...prognostic value in human breast cancer. Annals of surgical oncology 2006, 13(6):802-808. 33. Gupta J, Robbins J, Jilling T, Seth P: TGFbeta-dependent

Roles of ER, SRC-1, and CBP Phosphorylation in Estrogen Receptor-Regulated Gene Expression

DTIC Science & Technology

1999-06-01

J. S. Sutcliff, P. Fang, R. J. Galjaard, Y. H. Jiang, C. S. localization of three repair genes: the xeroderma pigmentosum group C gene Benton, J. M...receptor-mediated scription efficiency, a central DNA-binding domain, which me- transcription; SRC-1, p300/CBP, and RAC3/ACTR/AIB1 pos - diates receptor

Transfer-Free Batch Fabrication of Large-Area Suspended Graphene Membranes

DTIC Science & Technology

2010-01-01

Sikes, K. J.; Jiang, Z.; Klima, M.; Fudenberg, G.; Hone, J.; Kim, P.; Stormer , H. L. Ultrahigh Electron Mobility in Suspended Graphene. Solid State...Commun. 2008, 146, 351–355. 14. Bolotin, K. I.; Ghahari, F.; Shulman, M. D.; Stormer , H. L.; Kim, P. Observation of the Fractional Quantum Hall Effect in

The Voice of Feedback: A Study of Asynchronous Audio Communication in the Online Classroom

ERIC Educational Resources Information Center

Johnson Van Den Elzen, Jolene M.

2011-01-01

The interaction between learners and the instructor in an online learning environment has been shown to contribute to increases in learning through promotion of a cooperative and collaborative environment, which allows students to learn from course materials, the instructor, and each other (Jiang & Ting, 2000; Jung et al., 2002; Kollock, 1998;…

A new lead to NLRP3 inhibition

PubMed Central

2017-01-01

The discovery of a small molecule inhibitor that targets the inflammasome sensor NLRP3 offers a new path for the development of selective inflammasome blockers with potential therapeutic benefit in a wide range of human diseases (in this issue, see Jiang et al., https://doi.org/10.1084/jem.20171419). PMID:29061692

The Quest for World Class Universities in China: Critical Reflections

ERIC Educational Resources Information Center

Ngok, Kinglun; Guo, Weiqing

2008-01-01

Building world-class universities has become a national policy priority in China since then-President Jiang Zemin announced in May 1998 that China must have several world-class universities of international advanced level. This article aims to offer critical reflections on the policy in relation to building world-class universities in China. It…

Robust SERS Enhancement Factor Statistics Using Rotational Correlation Spectroscopy

DTIC Science & Technology

2012-05-02

Polymer coatings quench the reaction , preventing further aggregation when a Raman active molecule is added. (B) The bulk Raman spectrum of MBA in...Schrof, W. J. Phys. Chem. A 2001, 105, 3673. (12) Jiang, J.; Bosnick, K.; Maillard , M.; Brus, L. J. Phys. Chem. B 2003, 107, 9964. (13) Talley, C. E

Intracranial AAV-sTRAIL combined with lanatoside C prolongs survival in an orthotopic xenograft mouse model of invasive glioblastoma.

PubMed

Crommentuijn, Matheus H W; Maguire, Casey A; Niers, Johanna M; Vandertop, W Peter; Badr, Christian E; Würdinger, Thomas; Tannous, Bakhos A

2016-04-01

Glioblastoma (GBM) is the most common malignant brain tumor in adults. We designed an adeno-associated virus (AAV) vector for intracranial delivery of secreted, soluble tumor necrosis factor-related apoptosis-inducing ligand (sTRAIL) to GBM tumors in mice and combined it with the TRAIL-sensitizing cardiac glycoside, lanatoside C (lan C). We applied this combined therapy to two different GBM models using human U87 glioma cells and primary patient-derived GBM neural spheres in culture and in orthotopic GBM xenograft models in mice. In U87 cells, conditioned medium from AAV2-sTRAIL expressing cells combined with lan C induced 80% cell death. Similarly, lan C sensitized primary GBM spheres to sTRAIL causing over 90% cell death. In mice bearing intracranial U87 tumors treated with AAVrh.8-sTRAIL, administration of lan C caused a decrease in tumor-associated Fluc signal, while tumor size increased within days of stopping the treatment. Another round of lan C treatment re-sensitized GBM tumor to sTRAIL-induced cell death. AAVrh.8-sTRAIL treatment alone and combined with lanatoside C resulted in a significant decrease in tumor growth and longer survival of mice bearing orthotopic invasive GBM brain tumors. In summary, AAV-sTRAIL combined with lanatoside C induced cell death in U87 glioma cells and patient-derived GBM neural spheres in culture and in vivo leading to an increased in overall mice survival. Copyright © 2015 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.

Morphosyntax can modulate the N400 component: Event related potentials to gender-marked post-nominal adjectives

PubMed Central

Guajardo, Lourdes F.; Wicha, Nicole Y. Y.

2014-01-01

Event-related potential studies of grammatical gender agreement often report a left anterior negativity (LAN) when agreement violations occur. Some studies have shown that during sentence comprehension gender violations can also interact with semantic processing to modulate a negativity associated with processing meaning – the N400. Given that the LAN and N400 overlap in time, they are identified by their scalp distributions and purported functional roles. Critically, grammatical gender violations also elicit a right posterior positivity that can overlap temporally with and potentially affect the scalp distribution of the LAN/N400. We measured the effect of grammatical gender violations in the LAN/N400 window and late positive component (LPC) during comprehension of Spanish sentences. A post-nominal adjective could either make sense or not, and either agree or disagree in gender with the preceding noun. We observed a negativity to gender agreement violations in the LAN/N400 window (300–500 ms post stimulus onset) that was smaller than the semantic-congruity N400, but overlapped with it in time and distribution. The early portion of the LPC to gender violations was modulated by sentence constraint, occurring as early as 450ms in highly constraining sentences. A subadditive interaction occurred at the later portion of the LPC with equivalent effects for single and double violations (gender and semantics), reflecting a general stage of reprocessing. Overall, our data support models of language comprehension whereby both semantic and morphosyntactic information can affect processing at similar time points. PMID:24462934

Morphosyntax can modulate the N400 component: event related potentials to gender-marked post-nominal adjectives.

PubMed

Guajardo, Lourdes F; Wicha, Nicole Y Y

2014-05-01

Event-related potential studies of grammatical gender agreement often report a left anterior negativity (LAN) when agreement violations occur. Some studies have shown that during sentence comprehension gender violations can also interact with semantic processing to modulate a negativity associated with processing meaning - the N400. Given that the LAN and N400 overlap in time, they are identified by their scalp distributions and purported functional roles. Critically, grammatical gender violations also elicit a right posterior positivity that can overlap temporally and potentially affect the scalp distribution of the LAN/N400. We measured the effect of grammatical gender violations in the LAN/N400 window and late positive component (LPC) during comprehension of Spanish sentences. A post-nominal adjective could either make sense or not, and either agree or disagree in gender with the preceding noun. We observed a negativity to gender agreement violations in the LAN/N400 window (300-500ms post stimulus onset) that was smaller than the semantic-congruity N400, but overlapped with it in time and distribution. The early portion of the LPC to gender violations was modulated by sentence constraint, occurring as early as 450ms in highly constraining sentences. A subadditive interaction occurred at the later portion of the LPC with equivalent effects for single and double violations (gender and semantics), reflecting a general stage of reprocessing. Overall, our data support models of language comprehension whereby both semantic and morphosyntactic information can affect processing at similar time points. Copyright © 2014 Elsevier Inc. All rights reserved.

Los Alamos National Security, LLC Request for Information from industrial entities that desire to commercialize Laboratory-developed Extremely Low Resource Optical Identifier (ELROI) tech

DOE Office of Scientific and Technical Information (OSTI.GOV)

Erickson, Michael Charles

Los Alamos National Security, LLC (LANS) is the manager and operator of the Los Alamos National Laboratory for the U.S. Department of Energy National Nuclear Security Administration under contract DE-AC52-06NA25396. LANS is a mission-centric Federally Funded Research and Development Center focused on solving the most critical national security challenges through science and engineering for both government and private customers.

Development Of Fiber Optics For Passenger Car Applications

NASA Astrophysics Data System (ADS)

Steele, R. E.; Schmitt, H. J.

1987-12-01

The benefits of fiber optics for telecommunications and Local Area Networks (LANs) are well documented. The benefits to passenger car applications are not as clearly defined. This paper examines the differences between Telecommunications, LAN, and automotive point to point and network applications. Current production automotive applications of optics and fiber optics, automotive data communications trends, and both functional and non-functional requirements and constraints will be described.

A secure and robust password-based remote user authentication scheme using smart cards for the integrated EPR information system.

PubMed

Das, Ashok Kumar

2015-03-01

An integrated EPR (Electronic Patient Record) information system of all the patients provides the medical institutions and the academia with most of the patients' information in details for them to make corrective decisions and clinical decisions in order to maintain and analyze patients' health. In such system, the illegal access must be restricted and the information from theft during transmission over the insecure Internet must be prevented. Lee et al. proposed an efficient password-based remote user authentication scheme using smart card for the integrated EPR information system. Their scheme is very efficient due to usage of one-way hash function and bitwise exclusive-or (XOR) operations. However, in this paper, we show that though their scheme is very efficient, their scheme has three security weaknesses such as (1) it has design flaws in password change phase, (2) it fails to protect privileged insider attack and (3) it lacks the formal security verification. We also find that another recently proposed Wen's scheme has the same security drawbacks as in Lee at al.'s scheme. In order to remedy these security weaknesses found in Lee et al.'s scheme and Wen's scheme, we propose a secure and efficient password-based remote user authentication scheme using smart cards for the integrated EPR information system. We show that our scheme is also efficient as compared to Lee et al.'s scheme and Wen's scheme as our scheme only uses one-way hash function and bitwise exclusive-or (XOR) operations. Through the security analysis, we show that our scheme is secure against possible known attacks. Furthermore, we simulate our scheme for the formal security verification using the widely-accepted AVISPA (Automated Validation of Internet Security Protocols and Applications) tool and show that our scheme is secure against passive and active attacks.

Unconstrained Structural Equation Models of Latent Interactions: Contrasting Residual- and Mean-Centered Approaches

ERIC Educational Resources Information Center

Marsh, Herbert W.; Wen, Zhonglin; Hau, Kit-Tai; Little, Todd D.; Bovaird, James A.; Widaman, Keith F.

2007-01-01

Little, Bovaird and Widaman (2006) proposed an unconstrained approach with residual centering for estimating latent interaction effects as an alternative to the mean-centered approach proposed by Marsh, Wen, and Hau (2004, 2006). Little et al. also differed from Marsh et al. in the number of indicators used to infer the latent interaction factor…

Research Trends in Science Education from 2003 to 2007: A Content Analysis of Publications in Selected Journals

ERIC Educational Resources Information Center

Lee, Min-Hsien; Wu, Ying-Tien; Tsai, Chin-Chung

2009-01-01

The present study was a follow-up to Tsai and Wen's (2005) earlier research, in which 802 articles published in the "International Journal of Science Education," "Science Education," and the "Journal of Research in Science Teaching" from 1998 to 2002 were analysed in terms of author's nationality, research type, and research topic. In the present…

Genetics Home Reference: primary coenzyme Q10 deficiency

MedlinePlus

... q10 deficiency. Mol Syndromol. 2014 Jul;5(3-4):156-62. doi: 10.1159/000362826. Citation on PubMed or Free article on PubMed Central Emmanuele V, López LC, Berardo A, Naini A, Tadesse S, Wen B, D'Agostino E, Solomon M, DiMauro S, Quinzii C, Hirano M. Heterogeneity of ...

Using the Flipped Classroom to Enhance EFL Learning

ERIC Educational Resources Information Center

Chen Hsieh, Jun Scott; Wu, Wen-Chi Vivian; Marek, Michael W.

2017-01-01

Instruction in English is a priority around the globe, but instructional methodologies have not always kept pace with the changing needs of students. To explore the benefits of the flipped classroom model for learners of English as a Foreign Language, the researchers used flipped learning and Wen's Output-driven/Input-enabled model to design a…

The Use of Autonomous Vehicles for Spatially Measuring Mean Velocity Profiles in Rivers and Estuaries

DTIC Science & Technology

2011-09-01

Advisor: Jaime MacMahan Second Reader: Ed Thornton THIS PAGE INTENTIONALLY LEFT BLANK i REPORT DOCUMENTATION PAGE Form Approved OMB No. 0704-0188...Currents. IEEE J. Ocean. Eng. 26(4), 752–768. Eriksen, C. C., Osse, T. J., Light, R. D., Wen, T., Lehman, T. W., Sabin , P. L., Ballard, J. W., Chiodi

An Empirical Study on the Projection of Specificity in the Usage of Modifiers in Chinese College EFL Writing

ERIC Educational Resources Information Center

Ningling, Wei

2015-01-01

Specificity, as a dimension of cognitive construal, refers to the capacity of a speaker to describe an entity or a situation in different accuracy and details (Langacker, 2008), which is linguistically reflected in lexical and grammatical levels (Wen, 2012). Modifiers can extend a simple sentence into a long and complicated one (Weng, 2007),…

Vitamin D Levels and Related Genetic Polymorphisms, Sun Exposure, Skin Color, and Risk of Aggressive Prostate Cancer

DTIC Science & Technology

2012-07-01

for our specific aims. 15. SUBJECT TERMS vitamin D deficiency, prostate cancer, health disparities, African American 16. SECURITY CLASSIFICATION OF...ler.reb (If - 0.43 wen aJECia6!d with ~ iota re.icleaa~ in tbe lropi.:. (~- 5.60, p- 114), &t:.ry vibnoio D iobsb @- 0.01, p- ,OJ); IIILd supplmu1Ji

Dynamic performance and mechanical model analysis of a shear thickening fluid damper

NASA Astrophysics Data System (ADS)

Zhao, Qian; He, Yonghui; Yao, Hongliang; Wen, Bangchun

2018-07-01

This paper presents an experimental study of the dynamic performance of a self-developed shear thickening fluid (STF) damper and its mechanical model was proposed by nonlinear fitting. First, STF samples with different mass fraction and dispersion medium were fabricated by nano fumed silica and polyethylene glycol, and its rheological properties were investigated by a rheometer. Second, a smart STF damper was developed and manufactured. Its dynamic properties were experimentally investigated by establishing a vibration test bench, and results indicated that the STF damper can output variable damping force by controlling the loading frequency, loading amplitude and fluid gap. Third, the Bouc–Wen model was proposed to address the dynamic properties of STF damper, and mechanical model analysis was carried out by comparing several fitting functions. It verified that the Bouc–Wen hysteresis model can be better used to describe the nonlinear stiffness, nonlinear damping and rate-dependence characteristics of the STF damper. All these investigations can offer an effective guidance for further theoretical and application study of the smart STF damper in energy dissipation fields.

"Shape function + memory mechanism"-based hysteresis modeling of magnetorheological fluid actuators

NASA Astrophysics Data System (ADS)

Qian, Li-Jun; Chen, Peng; Cai, Fei-Long; Bai, Xian-Xu

2018-03-01

A hysteresis model based on "shape function + memory mechanism" is presented and its feasibility is verified through modeling the hysteresis behavior of a magnetorheological (MR) damper. A hysteresis phenomenon in resistor-capacitor (RC) circuit is first presented and analyzed. In the hysteresis model, the "memory mechanism" originating from the charging and discharging processes of the RC circuit is constructed by adopting a virtual displacement variable and updating laws for the reference points. The "shape function" is achieved and generalized from analytical solutions of the simple semi-linear Duhem model. Using the approach, the memory mechanism reveals the essence of specific Duhem model and the general shape function provides a direct and clear means to fit the hysteresis loop. In the frame of the structure of a "Restructured phenomenological model", the original hysteresis operator, i.e., the Bouc-Wen operator, is replaced with the new hysteresis operator. The comparative work with the Bouc-Wen operator based model demonstrates superior performances of high computational efficiency and comparable accuracy of the new hysteresis operator-based model.

Security Analysis and Improvement of 'a More Secure Anonymous User Authentication Scheme for the Integrated EPR Information System'.

PubMed

Islam, S K Hafizul; Khan, Muhammad Khurram; Li, Xiong

2015-01-01

Over the past few years, secure and privacy-preserving user authentication scheme has become an integral part of the applications of the healthcare systems. Recently, Wen has designed an improved user authentication system over the Lee et al.'s scheme for integrated electronic patient record (EPR) information system, which has been analyzed in this study. We have found that Wen's scheme still has the following inefficiencies: (1) the correctness of identity and password are not verified during the login and password change phases; (2) it is vulnerable to impersonation attack and privileged-insider attack; (3) it is designed without the revocation of lost/stolen smart card; (4) the explicit key confirmation and the no key control properties are absent, and (5) user cannot update his/her password without the help of server and secure channel. Then we aimed to propose an enhanced two-factor user authentication system based on the intractable assumption of the quadratic residue problem (QRP) in the multiplicative group. Our scheme bears more securities and functionalities than other schemes found in the literature.

Marking the enemy, marking the other : the intersection of national security and diversity.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wilson, G. D.

2001-01-01

In recent years, Los Alamos National Laboratory (LANL) has alternately been criticized for being too cozy with foreign scientists and too quick to scapegoat or profile workers with foreign ancestries. In the wake of the investigation of alleged espionage that focused on Taiwanese-born American nuclear scientist Wen Ho Lee, political leaders and the news media questioned the Lab's commitment to security and the wisdom of its close collaborations with foreign scientists. Wen Ho Lee was of course an American citizen and not a foreign scientist, and many of his supporters felt that his Asian ancestry made him too convenient ofmore » a target in a case focused on Chinese espionage. Thus, charges of racial profiling and scapegoating were also aimed at the Lab, the Department of Energy, and the Federal Bureau of Investigation. In the wake of the controversy some Asian American groups have been encouraging a boycott of the national laboratories run by the Department of Energy, and at Los Alamos, the number of Asian Americans applying for jobs, post docs, and student positions is substantially down.« less

LANL Institutional Decision Support By Process Modeling and Analysis Group (AET-2)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Booth, Steven Richard

2016-04-04

AET-2 has expertise in process modeling, economics, business case analysis, risk assessment, Lean/Six Sigma tools, and decision analysis to provide timely decision support to LANS leading to continuous improvement. This capability is critical during the current tight budgetary environment as LANS pushes to identify potential areas of cost savings and efficiencies. An important arena is business systems and operations, where processes can impact most or all laboratory employees. Lab-wide efforts are needed to identify and eliminate inefficiencies to accomplish Director McMillan’s charge of “doing more with less.” LANS faces many critical and potentially expensive choices that require sound decision supportmore » to ensure success. AET-2 is available to provide this analysis support to expedite the decisions at hand.« less

Secure environment for real-time tele-collaboration on virtual simulation of radiation treatment planning.

PubMed

Ntasis, Efthymios; Maniatis, Theofanis A; Nikita, Konstantina S

2003-01-01

A secure framework is described for real-time tele-collaboration on Virtual Simulation procedure of Radiation Treatment Planning. An integrated approach is followed clustering the security issues faced by the system into organizational issues, security issues over the LAN and security issues over the LAN-to-LAN connection. The design and the implementation of the security services are performed according to the identified security requirements, along with the need for real time communication between the collaborating health care professionals. A detailed description of the implementation is given, presenting a solution, which can directly be tailored to other tele-collaboration services in the field of health care. The pilot study of the proposed security components proves the feasibility of the secure environment, and the consistency with the high performance demands of the application.

Does Current Scientific Evidence Support a Link Between Light at Night and Breast Cancer Among Female Night-Shift Nurses?

PubMed Central

Dickerman, Barbra; Liu, Jianghong

2014-01-01

Breast cancer is increasingly prevalent in industrialized regions of the world, and exposure to light at night (LAN) has been proposed as a potential risk factor. Epidemiological observations have documented an increased breast cancer risk among female night-shift workers, and strong experimental evidence for this relationship has also been found in rodent models. Indirect support for the LAN hypothesis comes from studies involving blind women, sleep duration, bedroom light levels, and community nighttime light levels. This article reviews the literature, discusses possible mechanisms of action, and provides recommendations for occupational health nursing research, practice, and education. Research is needed to further explore the relationship between exposure to LAN and breast cancer risk and elucidate the mechanisms underlying this relationship before interventions can be designed for prevention and mitigation of breast cancer. PMID:22658734

In situ Raman Spectroscopy Study of the Formation of Graphene from Urea and Graphite Oxide

DTIC Science & Technology

2012-09-01

pp. 075404, Aug., 2006. [5] K. S. Novoselov, Z. Jiang, Y. Zhang, S. Morozov, H. Stormer , U. Zeitler, J. Maan, G. Boebinger, P. Kim, and A. Geim...Room-temperature quantum hall effect in graphene.” Science, vol. 315, no. 5817, pp. 1379, Mar., 2007. [6] Y. Zhang, Y. W. Tan, H. L. Stormer , and

A new lead to NLRP3 inhibition.

PubMed

Lamkanfi, Mohamed; Dixit, Vishva M

2017-11-06

The discovery of a small molecule inhibitor that targets the inflammasome sensor NLRP3 offers a new path for the development of selective inflammasome blockers with potential therapeutic benefit in a wide range of human diseases (in this issue, see Jiang et al., https://doi.org/10.1084/jem.20171419). © 2017 Lamkanfi and Dixit.

Exploring and Listening to Chinese Classical Ensembles in General Music

ERIC Educational Resources Information Center

Zhang, Wenzhuo

2017-01-01

Music diversity is valued in theory, but the extent to which it is efficiently presented in music class remains limited. Within this article, I aim to bridge this gap by introducing four genres of Chinese classical ensembles--Qin and Xiao duets, Jiang Nan bamboo and silk ensembles, Cantonese ensembles, and contemporary Chinese orchestras--into the…

On the limits of statistical learning: Intertrial contextual cueing is confined to temporally close contingencies.

PubMed

Thomas, Cyril; Didierjean, André; Maquestiaux, François; Goujon, Annabelle

2018-04-12

Since the seminal study by Chun and Jiang (Cognitive Psychology, 36, 28-71, 1998), a large body of research based on the contextual-cueing paradigm has shown that the cognitive system is capable of extracting statistical contingencies from visual environments. Most of these studies have focused on how individuals learn regularities found within an intratrial temporal window: A context predicts the target position within a given trial. However, Ono, Jiang, and Kawahara (Journal of Experimental Psychology, 31, 703-712, 2005) provided evidence of an intertrial implicit-learning effect when a distractor configuration in preceding trials N - 1 predicted the target location in trials N. The aim of the present study was to gain further insight into this effect by examining whether it occurs when predictive relationships are impeded by interfering task-relevant noise (Experiments 2 and 3) or by a long delay (Experiments 1, 4, and 5). Our results replicated the intertrial contextual-cueing effect, which occurred in the condition of temporally close contingencies. However, there was no evidence of integration across long-range spatiotemporal contingencies, suggesting a temporal limitation of statistical learning.

Composition and Free Radical Scavenging Activity of Kernel Oil from Torreya grandis, Carya Cathayensis, and Myrica Rubra

PubMed Central

Ni, Liang; Shi, Wei-Yong

2014-01-01

In this study, we measured the composition and free radical scavenging activity of several species of nuts, namely, Torreya grandis, Carya cathayensis, and Myrica rubra. The nut kernels of the aforementioned species are rich in fatty acids, particularly in unsaturated fatty acids, and have 51% oil content. T. grandis and C. cathayensis are mostly produced in ZheJiang province. The trace elements in the kernels of T. grandis and C. cathayensis were generally higher than those in M. rubra, except for Fe with a value of 64.41 mg/Kg. T. grandis is rich in selenium (52.91−68.71 mg/Kg). All three kernel oils have a certain free radical scavenging capacity, with the highest value in M. rubra. In the DPPH assay, the IC50 of M. rubra kernel oil was 60 μg/mL, and OH was 100 μg/mL. The results of this study provide basic data for the future development of the edible nut resources in ZheJiang province. PMID:24734074

Rethinking Mobile Telephony with the IMP

DTIC Science & Technology

2011-01-01

in the telephony industry, and portions of it such as SS7 or SCTP signaling are packet-switched, deployed mobile telephony access infrastructure is...deployment of wireless LAN technology raises the question of how a mobile telephony system might instead be architected to use wireless LAN access ...and wireless access points has made universal Internet access increasingly convenient. There are clearly barriers to this vision of accessing a

UTC Time Transfer for High Frequency Trading Using IS-95 CDMA Base Station Transmissions and IEEE-1588 Precision Time Protocol

DTIC Science & Technology

2010-11-01

CDMA base stations are each synchronized by GPS receivers, they provide an indirect link to GPS system time and UTC time . The major stock...antenna synchronizes the Local Area Network (LAN) to within 10 microseconds of UTC using the IEEE-1588 Precision Time Protocol (PTP). This is an...activities. Understanding and measuring latency on the LAN is key to the success of HFTs. Without precise time synchronization below 1 millisecond

Forensic Carving of Network Packets and Associated Data Structures

DTIC Science & Technology

2011-01-01

establishment of prior connection activity and services used; identification of other systems present on the system’s LAN or WLAN; geolocation of the...identification of other systems present on the system?s LAN or WLAN; geolocation of the host computer system; and cross-drive analysis. We show that network...Finally, our work in geolocation was assisted by geo- location databases created by companies such as Google (Google Mobile, 2011) and Skyhook

A Novel Anti-Beta2-Microglobulin Antibody Inhibition of Androgen Receptor Expression, Survival, and Progression in Prostate Cancer Cells

DTIC Science & Technology

2012-01-01

Los Angeles, CA 90048 REPORT DATE: January 2012 TYPE OF REPORT...Wen-Chin Huang, Ph.D. Cedars-Sinai Medical Center Los Angeles, CA 90048 W81XWH-08-1-0321 1 May 2008 - 2 Dec 2011Final01-01-2012 Abstract on next...NUMBER Cedars-Sinai Medical Center, Los Angeles, California 90048 9. SPONSORING / MONITORING AGENCY NAME(S) AND

Thin Film Magnetless Faraday Rotators for Compact Heterogeneous Integrated Optical Isolators (Postprint)

DTIC Science & Technology

2017-06-15

film garnet materials with zero birefringence for magneto-optic waveguide devices,” J. Appl. Phys. 63, 3099–3103 ( 1988 ). 5R. Wolfe, R. A. Lieberman, V...Approved for public release (PA): distribution unlimited. 11L. Bi, J. Hu, P. Jiang, D. H. Kim, G. F. Dionne, L. C. Kimerling, and C. A. Ross , “On-chip

Neural Control of Rising and Falling Tones in Mandarin Speakers Who Stutter

ERIC Educational Resources Information Center

Howell, Peter; Jiang, Jing; Peng, Danling; Lu, Chunming

2012-01-01

Neural control of rising and falling tones in Mandarin people who stutter (PWS) was examined by comparing with that which occurs in fluent speakers [Howell, Jiang, Peng, and Lu (2012). Neural control of fundamental frequency rise and fall in Mandarin tones. "Brain and Language, 121"(1), 35-46]. Nine PWS and nine controls were scanned. Functional…

Nonlinear Laser Spectroscopy Studies of Semiconductor Heterostructures

DTIC Science & Technology

1993-01-14

AGENCY NAME(S) AND AODOAVSS(E) IL. s9oN5ISMONOOUU AFOSR/NE AGOK 4gkT NUSeA 110 Duncan Avenue Suite B115 Bolling AFB DC 20332-0001 Howard Schlossberg...Quantum Well Laser," Conference on Quantum Electronics and Laser Science (QELS󈨡). Min Jiang, ttailin Wang, Roberto Merlin, D.G. Steel, "Nonlinear

Asymmetry in Object Substitution Masking Occurs Relative to the Direction of Spatial Attention Shift

ERIC Educational Resources Information Center

Hirose, Nobuyuki; Osaka, Naoyuki

2010-01-01

A sparse mask that persists beyond the duration of a target can reduce its visibility, a phenomenon called "object substitution masking". Y. Jiang and M. M. Chun (2001a) found an asymmetric pattern of substitution masking such that a mask on the peripheral side of the target caused stronger substitution masking than on the central side.…

Exploring and Exploiting the Protein S100A7 as a New Target for Breast Cancer Therapy

DTIC Science & Technology

2010-01-01

Proteomics of human breast ductal carcinoma in situ. Cancer Research 62, 6740–6749. 2. Jiang, W. G., Watkins , G., Douglas-Jones, A., and Mansel, R. E...negative invasive breast cancer. Clin Cancer Res 9: 2627–2631. Enerbäck C, Porter DA, Seth P, Sgroi D, Gaudet J, Weremowicz S et al. (2002). Psoriasin

Flexible SERS Substrates: Challenges and Opportunities

DTIC Science & Technology

2016-01-28

interactions between the analyte, silver nanoparticles , and a salt. This system has also been applied to detection of trace antibiotics for food safety...Cleanable SERS Substrates Based on Silver Nanoparticle Decorated Electrospun Nano-fibrous Membranes Chaoyang Jiang Porous electrospun nanofibrous...present our recent work on the preparation, characterization, and SERS activity of silver nanoparticle decorated polymeric electrospun nanofibers

Electron Transport in Graphene From a Diffusion-Drift Perspective

DTIC Science & Technology

2010-02-24

Tung, M.E. Schwartz, M. Takita, Y.-J. Wang, P. Kim, and H.L. Stormer , “Cyclotron resonance in bilayer graphene,” Phys. Rev. Lett. 100, 087403 (2008...Dec. 2004. [3] K. I. Bolotin, K. J. Sikes, Z. Jiang, M. Klima, G. Fudenberg, J. Hone, P. Kim, and H. L. Stormer , “Ultrahigh electron mobility in

Colloquium: Quantum Networks with Trapped Ions

DTIC Science & Technology

2010-04-28

observed be- tween two ions held in the same trap Eichmann et al., 1993; DeVoe and Brewer, 1996. Type-II links have the advantage of being less sensitive...Childress, E. Jiang, J. Togan, J. Maze, F. Jelezko, A. S. Zibrov, P. R. Hemmer, and M. D. Lukin, 2007, Science 316, 1312. Eichmann , U., J. C. Bergquist

A Study of Refusal Speech Act in Chinese Dating Programs--Take "If You Are the One" as an Example

ERIC Educational Resources Information Center

Wang, Yiwen

2015-01-01

Looking at the development of China dating programs, "If You Are The One" in Jiang Su satellite TV is the heated program drawing much attention from the public. There are some papers focusing on the dialogue in the program from the perspective of linguistic features or pragmatic function, but there are few papers on the refusal speech…

15 CFR Supplement No. 7 to Part 748 - Authorization Validated End-User (VEU): List of Validated End-Users, Respective Items Eligible...

Code of Federal Regulations, 2010 CFR

2010-01-01

...; 2B230; 2B350.d.2 2B350.g.3 2B350.i.4; 3B001.c.2; 3C002; 3C004 Headquarters and Fab. 1 of HHNEC, No. 1188 Chuan Qiao Rd., Pu Dong, Shanghai, China 201206.Fab. 2 of HHNEC, No. 668 Guo Shou Jing Rd., Zhang Jiang...

Study of atmospheric CH4 mole fractions at three WMO/GAW stations in China

NASA Astrophysics Data System (ADS)

Fang, Shuang-Xi; Zhou, Ling-Xi; Masarie, Kenneth A.; Xu, Lin; Rella, Chris W.

2013-05-01

CH4 mole fractions were continuously measured from 2009 to 2011 at three WMO/GAW stations in China (Lin'an, LAN; Longfengshan, LFS; and Waliguan, WLG) using three Cavity Ring Down Spectroscopy instruments. LAN and LFS are GAW regional measurement stations. LAN is located in China's most economically developed region, and LFS is in a rice production area (planting area > 40,000 km2). WLG is a global measurement station in remote northwest China. At LAN, high methane mole fractions are observed in all seasons. Surface winds from the northeast enhance CH4 values, with a maximum increase of 32 ± 15 ppb in summer. The peak to peak amplitude of the seasonal cycle is 77 ± 35 ppb. At LFS, the diurnal cycle amplitude is approximately constant throughout the year except summer, when a value of 196 ± 65 ppb is observed. CH4 values at LFS reach their peak in July, which is different from seasonal variations typically observed in the northern hemisphere. CH4 mole fractions at WLG show both the smallest values and the lowest variability. Maximum values occur during summer, which is different from other northern hemisphere WMO/GAW global stations. The seasonal cycle amplitude is 17 ± 11 ppb. The linear growth rates at LAN, LFS, and WLG are 8.0 ± 1.2, 7.9 ± 0.9, and 9.4 ± 0.2 ppb yr-1, respectively, which are all larger than the global mean over the same 3 year period. Results from this study attempt to improve our basic understanding of observed atmospheric CH4 in China.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dasari, Paul K. R.; Shazeeb, Mohammed Salman; Könik, Arda

Purpose: Binning list-mode acquisitions as a function of a surrogate signal related to respiration has been employed to reduce the impact of respiratory motion on image quality in cardiac emission tomography (SPECT and PET). Inherent in amplitude binning is the assumption that there is a monotonic relationship between the amplitude of the surrogate signal and respiratory motion of the heart. This assumption is not valid in the presence of hysteresis when heart motion exhibits a different relationship with the surrogate during inspiration and expiration. The purpose of this study was to investigate the novel approach of using the Bouc–Wen (BW)more » model to provide a signal accounting for hysteresis when binning list-mode data with the goal of thereby improving motion correction. The study is based on the authors’ previous observations that hysteresis between chest and abdomen markers was indicative of hysteresis between abdomen markers and the internal motion of the heart. Methods: In 19 healthy volunteers, they determined the internal motion of the heart and diaphragm in the superior–inferior direction during free breathing using MRI navigators. A visual tracking system (VTS) synchronized with MRI acquisition tracked the anterior–posterior motions of external markers placed on the chest and abdomen. These data were employed to develop and test the Bouc–Wen model by inputting the VTS derived chest and abdomen motions into it and using the resulting output signals as surrogates for cardiac motion. The data of the volunteers were divided into training and testing sets. The training set was used to obtain initial values for the model parameters for all of the volunteers in the set, and for set members based on whether they were or were not classified as exhibiting hysteresis using a metric derived from the markers. These initial parameters were then employed with the testing set to estimate output signals. Pearson’s linear correlation coefficient

A pilot study for the integration of cytometry reports in digital cytology telemedicine applications.

PubMed

Giansanti, Daniele; Cerroni, Fabio; Amodeo, Rachele; Filoni, Marco; Giovagnoli, Maria Rosaria

2010-01-01

Up to date, tele-pathology in the three different forms of application, "dynamic", "static" and "virtual microscopy" has been mainly based on tele-hystology remote consulting. Today the diffusion of specialized WAN connections is guiding the research of new applications of tele-pathology. A specific analysis has been conducted, focused on digital cytology, in the biomedical laboratory of Sant'Andrea Hospital to investigate the technologies potentially useful to integrate in the LAN/WAN for telemedicine applications. Among the possible tools useful to be integrated in the LAN/WAN for telemedicine applications, the cytometry equipment available in the technical unity of cytometry has been considered important. The study finally provides a proposal for a tele-consulting architecture for the integration of cytometry reports both in the hospital LAN and the WAN for possible cooperative diagnosis and second opinion support.

Validation of the European Prototype for Integrated Care at Municipal Level in Savona: Updating and Maintenance

DTIC Science & Technology

2001-10-25

within one of the programmes sponsored by the European Commission.The system mainly consists of a shared care database in which each groups of...care database in which each community facility, or group of facilities, is supported by a local area network (LAN). Each of these LANs is connected over...functions. The software is layered, so that the client application is not affected by how the servers are implemented or which database system they use

An Abstract Model of Rogue Code Insertion into Radio Frequency Wireless Networks. The Effects of Computer Viruses on the Program Management Office

DTIC Science & Technology

1994-04-01

numerous articles on wireless LANs, only one by Lathrop discusses their vulnerabilities’. Lathrop’s paper provides an overview of wireless LANs and...to detect any action which deviates from the user’s observed recorded past behavior. These profiles list the operator’s commonly used commands, typing...current system activity audit records to rules describing past behavior patterns. W&S is especially effective in detecting rogue program penetrations. It

Monitoring Malware Activity on the LAN Network

NASA Astrophysics Data System (ADS)

Skrzewski, Mirosław

Many security related organizations periodically publish current network and systems security information, with the lists of top malware programs. These lists raises the question how these threats spreads out, if the worms (the only threat with own communication abilities) are low or missing on these lists. The paper discuss the research on malware network activity, aimed to deliver the answer to the question, what is the main infection channel of modern malware, done with the usage of virtual honeypot systems on dedicated, unprotected network. Systems setup, network and systems monitoring solutions, results of over three months of network traffic and malware monitoring are presented, along with the proposed answer to our research question.

Effectiveness of Acupressure Treatment for Pain Management and Fatigue Relief in Gulf War Veterans

DTIC Science & Technology

2013-10-01

measures. II. KEYWORDS Acupressure, Reiki , Gulf War Illness, fatigue, chronic headache, musculoskeletal pain, electroencephalography, non-invasive...Consultant) Ernie Betz (Consultant – Reiki ) Wenning Zhao (Consultant) Yin Fang PhD (Consultant) Vlodek Siemionow PhD (Consultant) Due to...Zhao and Ms. Alice Langholt were recruited to provide the Acupressure and Reiki interventions. Dr. Juliet Hou was recruited as a medical monitor

Expectation Maximization and its Application in Modeling, Segmentation and Anomaly Detection

DTIC Science & Technology

2008-05-01

ocomplNc <la!a rrot>lcm,. ",., i’lCOll\\l>lc,c,ICSS of Ihc dala mayan "" IIuc lu missing dala. (J,,,,,,.,ed di,nibu!ions . elc . 0"" such c • ..- is a...Estimation Techniques in Computer Huiyan, Z., Yongfeng, C., Wen, Y. SAR Image Segmentation Using MPM Constrained Stochastic Relaxation. Civil Engineering

Real-Time Aggressive Image Data Compression

DTIC Science & Technology

1990-03-31

implemented with higher degrees of modularity, concurrency, and higher levels of machine intelligence , thereby providing higher data -throughput rates...Project Summary Project Title: Real-Time Aggressive Image Data Compression Principal Investigators: Dr. Yih-Fang Huang and Dr. Ruey-wen Liu Institution...Summary The objective of the proposed research is to develop reliable algorithms !.hat can achieve aggressive image data compression (with a compression

The effect of dim light at night on cerebral hemodynamic oscillations during sleep: A near-infrared spectroscopy study.

PubMed

Kim, Tae-Joon; Lee, Byeong Uk; Sunwoo, Jun-Sang; Byun, Jung-Ick; Moon, Jangsup; Lee, Soon-Tae; Jung, Keun-Hwa; Chu, Kon; Kim, Manho; Lim, Jong-Min; Lee, Eunil; Lee, Sang Kun; Jung, Ki-Young

2017-01-01

Recent studies have reported that dim light at night (dLAN) is associated with risks of cardiovascular complications, such as hypertension and carotid atherosclerosis; however, little is known about the underlying mechanism. Here, we evaluated the effect of dLAN on the cerebrovascular system by analyzing cerebral hemodynamic oscillations using near-infrared spectroscopy (NIRS). Fourteen healthy male subjects underwent polysomnography coupled with cerebral NIRS. The data collected during sleep with dim light (10 lux) were compared with those collected during sleep under the control dark conditions for the sleep structure, cerebral hemodynamic oscillations, heart rate variability (HRV), and their electroencephalographic (EEG) power spectrum. Power spectral analysis was applied to oxy-hemoglobin concentrations calculated from the NIRS signal. Spectral densities over endothelial very-low-frequency oscillations (VLFOs) (0.003-0.02 Hz), neurogenic VLFOs (0.02-0.04 Hz), myogenic low-frequency oscillations (LFOs) (0.04-0.15 Hz), and total LFOs (0.003-0.15 Hz) were obtained for each sleep stage. The polysomnographic data revealed an increase in the N2 stage under the dLAN conditions. The spectral analysis of cerebral hemodynamics showed that the total LFOs increased significantly during slow-wave sleep (SWS) and decreased during rapid eye movement (REM) sleep. Specifically, endothelial (median of normalized value, 0.46 vs. 0.72, p = 0.019) and neurogenic (median, 0.58 vs. 0.84, p = 0.019) VLFOs were enhanced during SWS, whereas endothelial VLFOs (median, 1.93 vs. 1.47, p = 0.030) were attenuated during REM sleep. HRV analysis exhibited altered spectral densities during SWS induced by dLAN, including an increase in very-low-frequency and decreases in low-frequency and high-frequency ranges. In the EEG power spectral analysis, no significant difference was detected between the control and dLAN conditions. In conclusion, dLAN can disturb cerebral hemodynamics via the

Impact of Exposure to Dim Light at Night on Sleep in Female and Comparison with Male Subjects.

PubMed

Cho, Chul-Hyun; Yoon, Ho-Kyoung; Kang, Seung-Gul; Kim, Leen; Lee, Eun-Il; Lee, Heon-Jeong

2018-03-19

Light pollution has become a social and health issue. We performed an experimental study to investigate impact of dim light at night (dLAN) on sleep in female subjects, with measurement of salivary melatonin. The 25 female subjects (Group A: 12; Group B: 13 subjects) underwent a nocturnal polysomnography (NPSG) session with no light (Night 1) followed by an NPSG session randomly assigned to two conditions (Group A: 5; Group B: 10 lux) during a whole night of sleep (Night 2). Salivary melatonin was measured before and after sleep on each night. For further investigation, the female and male subjects of our previous study were collected (48 subjects), and differences according to gender were compared. dLAN during sleep was significantly associated with decreased total sleep time (TST; F=4.818, p=0.039), sleep efficiency (SE; F=5.072, p=0.034), and Stage R latency (F=4.664, p=0.041) for female subjects, and decreased TST (F=14.971, p<0.001) and SE (F=7.687, p=0.008), and increased wake time after sleep onset (F=6.322, p=0.015) and Stage R (F=5.031, p=0.03), with a night-group interaction (F=4.579, p=0.038) for total sample. However, no significant melatonin changes. There was no significant gender difference of the impact of dLAN on sleep, showing the negative changes in the amount and quality of sleep and the increase in REM sleep in the both gender group under 10 lux condition. We found a negative impact of exposure to dLAN on sleep in female as well as in merged subjects. REM sleep showed a pronounced increase under 10 lux than under 5 lux in merged subjects, suggesting the possibility of subtle influences of dLAN on REM sleep.

Preparing culture change agents for academic medicine in a multi-institutional consortium: the C - change learning action network.

PubMed

Pololi, Linda H; Krupat, Edward; Schnell, Eugene R; Kern, David E

2013-01-01

Research suggests an ongoing need for change in the culture of academic medicine. This article describes the structure, activities and evaluation of a culture change project: the C - Change Learning Action Network (LAN) and its impact on participants. The LAN was developed to create the experience of a culture that would prepare participants to facilitate a culture in academic medicine that would be more collaborative, inclusive, relational, and that supports the humanity and vitality of faculty. Purposefully diverse faculty, leaders, and deans from 5 US medical schools convened in 2 1/2-day meetings biannually over 4 years. LAN meetings employed experiential, cognitive, and affective learning modes; innovative dialogue strategies; and reflective practice aimed at facilitating deep dialogue, relationship formation, collaboration, authenticity, and transformative learning to help members experience the desired culture. Robust aggregated qualitative and quantitative data collected from the 5 schools were used to inform and stimulate culture-change plans. Quantitative and qualitative evaluation methods were used. Participants indicated that a safe, supportive, inclusive, collaborative culture was established in LAN and highly valued. LAN members reported a deepened understanding of organizational change, new and valued interpersonal connections, increased motivation and resilience, new skills and approaches, increased self-awareness and personal growth, emotional connection to the issues of diversity and inclusion, and application of new learnings in their work. A carefully designed multi-institutional learning community can transform the way participants experience and view institutional culture. It can motivate and prepare them to be change agents in their own institutions. Copyright © 2013 The Alliance for Continuing Education in the Health Professions, the Society for Academic Continuing Medical Education, and the Council on CME, Association for Hospital Medical

Expression of phosphodiesterase 6 (PDE6) in human breast cancer cells.

PubMed

Dong, Hongli; Claffey, Kevin P; Brocke, Stefan; Epstein, Paul M

2013-01-01

Considerable epidemiological evidence demonstrates a positive association between artificial light at night (LAN) levels and incidence rates of breast cancer, suggesting that exposure to LAN is a risk factor for breast cancer. There is a 30-50% higher risk of breast cancer in the highest LAN exposed countries compared to the lowest LAN countries, and studies showing higher incidence of breast cancer among shift workers exposed to more LAN have led the International Agency for Research on Cancer to classify shift work as a probable human carcinogen. Nevertheless, the means by which light can affect breast cancer is still unknown. In this study we examined established human breast cancer cell lines and patients' primary breast cancer tissues for expression of genetic components of phosphodiesterase 6 (PDE6), a cGMP-specific PDE involved in transduction of the light signal, and previously thought to be selectively expressed in photoreceptors. By microarray analysis we find highly significant expression of mRNA for the PDE6B, PDE6C, and PDE6D genes in both the cell lines and patients' tissues, minimal expression of PDE6A and PDE6G and no expression of PDE6H. Using antibody specific for PDE6β, we find expression of PDE6B protein in a wide range of patients' tissues by immunohistochemistry, and in MCF-7 breast cancer cells by immunofluorescence and Western blot analysis. Considerable expression of key circadian genes, PERIOD 2, CLOCK, TIMELESS, CRYPTOCHROME 1, and CRYPTOCHROME 2 was also seen in all breast cancer cell lines and all patients' breast cancer tissues. These studies indicate that genes for PDE6 and control of circadian rhythm are expressed in human breast cancer cells and tissues and may play a role in transducing the effects of light on breast cancer.

Event Detection Challenges, Methods, and Applications in Natural and Artificial Systems

DTIC Science & Technology

2009-03-01

using the composite event detection method [Kerman, Jiang, Blumberg , and Buttrey, 2009]. Although the techniques and utility of the...aforementioned method have been clearly demonstrated, there is still much work and research to be conducted within the realm of event detection. This...detection methods . The paragraphs that follow summarize the discoveries of and lessons learned by multiple researchers and authors over many

Malaria Genome Sequencing Project

DTIC Science & Technology

2004-01-01

BEHNAM JOANA JENKINS, CHELTON CARTY, HEATHER JENKINS, JENNIFER CHAUDHARY, ABHILASHA JIANG, LINGXIA CHEN, DAN JONES, KRISTINE CHEN, MINGHUA KALB, ERICA... JENNIFER SILVA, JOANA MOAZZEZ, AZITA SITZ, JEFF MOFFAT, KELLY SKOVORODNEV, NELSON, KEITH ALEXANDER NENE, VISHVANATH SMIRNOVA, TATYANA NORCUTT, KARA...Shallom*, Susan E. van Aken*, Steven B. Riedmuller*, Tamara V. Feldblyum*, Jennifer L Cho*t, John Quackenbush*, Martha Sedegah§, Azadeh Shoalbl*, Leda M

China/Taiwan: Evolution of the One China Policy - Key Statements from Washington, Beijing, and Taipei

DTIC Science & Technology

2006-09-07

Statements During Clinton Administration . . . . . . . . . . . . . . . . . . . . . . . . . 48 PRC Premier Li Peng Warns Taiwan...Soviet Union/Russia and built up its theater missile force.48 In December 1992 and March 1993, PRC President Jiang Zemin and Premier Li Peng began to...Ye Jianying Explains Policy Concerning Return of Taiwan to Motherland and Peaceful Unification,” Xinhua [New China News Agency], September 30, 1981

Boron Nitride Substrates for High Mobility Chemical Vapor Deposited Graphene

DTIC Science & Technology

2011-06-13

Hone, H. L. Stormer , and P. Kim, Phys. Rev. Lett. 101, 096802 2008. 5K. I. Bolotin, K. J. Sikes, Z. Jiang, M. Klima, G. Fudenberg, J. Hone, P. Kim, and...H. L. Stormer , Solid State Commun. 146, 351 2008. 6S. Berciaud, S. Ryu, L. E. Brus, and T. F. Heinz, Nano Lett. 9, 346 2009. 7S. Bae, H. Kim, Y

Electrical Control of Silicon Photonic Crystal Cavity by Graphene

DTIC Science & Technology

2012-01-01

Henriksen, E. A.; Jiang, Z.; Hao, Z.; Martin, M. C.; Kim, P.; Stormer , H. L.; Basov, D. N. Nat. Phys. 2008, 4 (7), 532−535. (4) Liu, M.; Yin, X...Zhang, Y.; Tan, Y.-W.; Stormer , H. L.; Kim, P. Nature 2005, 438 (7065), 201−204. (21) Cho, J. H.; Lee, J.; Xia, Y.; Kim, B.; He, Y.; Renn, M. J

Extraordinary magnetoresistance in shunted chemical vapor deposition grown graphene devices

DTIC Science & Technology

2011-07-01

Lett. 10, 3962 (2010). 9Z. Jiang, Y. Zhang, Y.-W. Tan, H. L. Stormer , and P. Kim, Solid State Commun. 143 14 (2007). 10A. K. Geim and K. S. Novoselov...L. Stormer , U. Zeitler, J. C. Maan, G. S. Boebinger, P. Kim, and A. K. Geim, Science 9, 1379 (2007). 20F. Meier, L. Zhou, J. Wiebe, and R

AR Alternative Splicing and Prostate Cancer Progression

DTIC Science & Technology

2012-07-01

database (ARDB): update. Human Mutation 23 527–533. (doi:10.1002/ humu .20044) Guo Z, Yang X, Sun F, Jiang R, Linn DE, Chen H, Kong X, Melamed J, Tepper...doi:10.1002/ humu .21138) Matias PM, Donner P, Coelho R, Thomaz M, Peixoto C, Macedo S, Otto N, Joschko S, Scholz P, Wegg A et al. 2000 Structural

Innovative Composite Structure Design for Blast Protection

DTIC Science & Technology

2007-01-01

2007-01-0483 Innovative Composite Structure Design for Blast Protection Dongying Jiang, Yuanyuan Liu MKP Structural Design Associates, Inc...protect vehicle and occupants against various explosives. The multi-level and multi-scenario blast simulation and design system integrates three major...numerical simulation of a BTR composite under a blast event. The developed blast simulation and design system will enable the prediction, design, and

Parallel Computing in Protein Structure Topology Determination

DTIC Science & Technology

2008-12-01

model, B) dynamic model. A B 6. REFERENCES Baker, M. L., W. Jiang, et al. (2006). "Ab initio modeling of the herpesvirus VP26 core...skeletons of secondary structures." J Mol Biol 350(3): 571-86. Zhou, Z. H., M. Dougherty, et al. (2000). "Seeing the herpesvirus capsid at 8.5 Å." Science 288(5467): 877-880.

English-Chinese Cross-Language IR Using Bilingual Dictionaries

DTIC Science & Technology

2006-01-01

specialized dictionaries together contain about two million entries [6]. 4 Monolingual Experiment The Chinese documents and the Chinese translations of... monolingual performance. The main performance-limiting factor is the limited coverage of the dictionary used in query translation. Some of the key con...English-Chinese Cross-Language IR using Bilingual Dictionaries Aitao Chen , Hailing Jiang , and Fredric Gey School of Information Management

Requirements for a network storage service

NASA Technical Reports Server (NTRS)

Kelly, Suzanne M.; Haynes, Rena A.

1991-01-01

Sandia National Laboratories provides a high performance classified computer network as a core capability in support of its mission of nuclear weapons design and engineering, physical sciences research, and energy research and development. The network, locally known as the Internal Secure Network (ISN), comprises multiple distributed local area networks (LAN's) residing in New Mexico and California. The TCP/IP protocol suite is used for inter-node communications. Scientific workstations and mid-range computers, running UNIX-based operating systems, compose most LAN's. One LAN, operated by the Sandia Corporate Computing Computing Directorate, is a general purpose resource providing a supercomputer and a file server to the entire ISN. The current file server on the supercomputer LAN is an implementation of the Common File Server (CFS). Subsequent to the design of the ISN, Sandia reviewed its mass storage requirements and chose to enter into a competitive procurement to replace the existing file server with one more adaptable to a UNIX/TCP/IP environment. The requirements study for the network was the starting point for the requirements study for the new file server. The file server is called the Network Storage Service (NSS) and its requirements are described. An application or functional description of the NSS is given. The final section adds performance, capacity, and access constraints to the requirements.

Dim light at night disturbs the daily sleep-wake cycle in the rat.

PubMed

Stenvers, Dirk Jan; van Dorp, Rick; Foppen, Ewout; Mendoza, Jorge; Opperhuizen, Anne-Loes; Fliers, Eric; Bisschop, Peter H; Meijer, Johanna H; Kalsbeek, Andries; Deboer, Tom

2016-10-20

Exposure to light at night (LAN) is associated with insomnia in humans. Light provides the main input to the master clock in the hypothalamic suprachiasmatic nucleus (SCN) that coordinates the sleep-wake cycle. We aimed to develop a rodent model for the effects of LAN on sleep. Therefore, we exposed male Wistar rats to either a 12 h light (150-200lux):12 h dark (LD) schedule or a 12 h light (150-200 lux):12 h dim white light (5 lux) (LDim) schedule. LDim acutely decreased the amplitude of daily rhythms of REM and NREM sleep, with a further decrease over the following days. LDim diminished the rhythms of 1) the circadian 16-19 Hz frequency domain within the NREM sleep EEG, and 2) SCN clock gene expression. LDim also induced internal desynchronization in locomotor activity by introducing a free running rhythm with a period of ~25 h next to the entrained 24 h rhythm. LDim did not affect body weight or glucose tolerance. In conclusion, we introduce the first rodent model for disturbed circadian control of sleep due to LAN. We show that internal desynchronization is possible in a 24 h L:D cycle which suggests that a similar desynchronization may explain the association between LAN and human insomnia.

Dim light at night disturbs the daily sleep-wake cycle in the rat

PubMed Central

Jan Stenvers, Dirk; van Dorp, Rick; Foppen, Ewout; Mendoza, Jorge; Opperhuizen, Anne-Loes; Fliers, Eric; Bisschop, Peter H.; Meijer, Johanna H.; Kalsbeek, Andries; Deboer, Tom

2016-01-01

Exposure to light at night (LAN) is associated with insomnia in humans. Light provides the main input to the master clock in the hypothalamic suprachiasmatic nucleus (SCN) that coordinates the sleep-wake cycle. We aimed to develop a rodent model for the effects of LAN on sleep. Therefore, we exposed male Wistar rats to either a 12 h light (150–200lux):12 h dark (LD) schedule or a 12 h light (150–200 lux):12 h dim white light (5 lux) (LDim) schedule. LDim acutely decreased the amplitude of daily rhythms of REM and NREM sleep, with a further decrease over the following days. LDim diminished the rhythms of 1) the circadian 16–19 Hz frequency domain within the NREM sleep EEG, and 2) SCN clock gene expression. LDim also induced internal desynchronization in locomotor activity by introducing a free running rhythm with a period of ~25 h next to the entrained 24 h rhythm. LDim did not affect body weight or glucose tolerance. In conclusion, we introduce the first rodent model for disturbed circadian control of sleep due to LAN. We show that internal desynchronization is possible in a 24 h L:D cycle which suggests that a similar desynchronization may explain the association between LAN and human insomnia. PMID:27762290

A Wireless Electronic Nose System Using a Fe2O3 Gas Sensing Array and Least Squares Support Vector Regression

PubMed Central

Song, Kai; Wang, Qi; Liu, Qi; Zhang, Hongquan; Cheng, Yingguo

2011-01-01

This paper describes the design and implementation of a wireless electronic nose (WEN) system which can online detect the combustible gases methane and hydrogen (CH4/H2) and estimate their concentrations, either singly or in mixtures. The system is composed of two wireless sensor nodes—a slave node and a master node. The former comprises a Fe2O3 gas sensing array for the combustible gas detection, a digital signal processor (DSP) system for real-time sampling and processing the sensor array data and a wireless transceiver unit (WTU) by which the detection results can be transmitted to the master node connected with a computer. A type of Fe2O3 gas sensor insensitive to humidity is developed for resistance to environmental influences. A threshold-based least square support vector regression (LS-SVR)estimator is implemented on a DSP for classification and concentration measurements. Experimental results confirm that LS-SVR produces higher accuracy compared with artificial neural networks (ANNs) and a faster convergence rate than the standard support vector regression (SVR). The designed WEN system effectively achieves gas mixture analysis in a real-time process. PMID:22346587

A Revised Checklist of Chigger Mites (Acari: Trombiculidae) From Thailand, with the Description of Three New Species.

PubMed

Chaisiri, Kittipong; Stekolnikov, Alexandr A; Makepeace, Benjamin L; Morand, Serge

2016-03-01

Chigger mites of Thailand were studied on the basis of larvae collected from 19 small mammal species (17 species of Rodentia, 1 species of Erinaceomorpha, and 1 species of Scandentia) and revision of published data. Samples of 38 trombiculid species were collected from 11 provinces. Three new species were described: Trombiculindus kosapani sp. nov., Helenicula naresuani sp. nov., and Walchia chavali sp. nov. Ten species were recorded in Thailand for the first time: Leptotrombidium sialkotense Vercammen-Grandjean and Langston, 1976; Leptotrombidium subangulare Wen and Xiang, 1984; Leptotrombidium tenompaki Stekolnikov, 2013; Leptotrombidium turdicola Vercammen-Grandjean and Langston, 1976; Leptotrombidium yunlingense Yu, Yang, Zhang and Hu, 1981; Lorillatum hekouensis Yu, Chen and Lin, 1996; Helenicula pilosa (Abonnenc and Taufflieb, 1957); Gahrliepia xiaowoi Wen and Xiang, 1984; Walchia minuscuta Chen, 1978; and Walchia ventralis (Womersley, 1952). In all, 99 chigger mite species were considered; the presence of 93 species was established in Thailand by original data or properly documented records in the scientific literature. Evidence for 64 species records of 147 from a previous checklist of Thai chiggers (Tanskul 1993) remains unknown. Distribution of chigger species by geographical regions of Thailand is discussed.

Network interface unit design options performance analysis

NASA Technical Reports Server (NTRS)

Miller, Frank W.

1991-01-01

An analysis is presented of three design options for the Space Station Freedom (SSF) onboard Data Management System (DMS) Network Interface Unit (NIU). The NIU provides the interface from the Fiber Distributed Data Interface (FDDI) local area network (LAN) to the DMS processing elements. The FDDI LAN provides the primary means for command and control and low and medium rate telemetry data transfers on board the SSF. The results of this analysis provide the basis for the implementation of the NIU.

Local network assessment

NASA Astrophysics Data System (ADS)

Glen, D. V.

1985-04-01

Local networks, related standards activities of the Institute of Electrical and Electronics Engineers the American National Standards Institute and other elements are presented. These elements include: (1) technology choices such as topology, transmission media, and access protocols; (2) descriptions of standards for the 802 local area networks (LAN's); high speed local networks (HSLN's) and military specification local networks; and (3) intra- and internetworking using bridges and gateways with protocols Interconnection (OSI) reference model. The convergence of LAN/PBX technology is also described.

Mean effects of turbulence on elliptic instability in fluids.

PubMed

Fabijonas, Bruce R; Holm, Darryl D

2003-03-28

Elliptic instability in fluids is discussed in the context of the Lagrangian-averaged Navier-Stokes-alpha (LANS-alpha) turbulence model. This model preserves the Craik-Criminale (CC) family of solutions consisting of a columnar eddy and a Kelvin wave. The LANS-alpha model is shown to preserve elliptic instability. However, the model shifts the critical stability angle. This shift increases (decreases) the maximum growth rate for long (short) waves. It also introduces a band of stable CC solutions for short waves.

Projective limits of state spaces III. Toy-models

NASA Astrophysics Data System (ADS)

Lanéry, Suzanne; Thiemann, Thomas

2018-01-01

In this series of papers, we investigate the projective framework initiated by Kijowski (1977) and Okołów (2009, 2014, 2013) [1,2], which describes the states of a quantum theory as projective families of density matrices. A short reading guide to the series can be found in Lanéry (2016). A strategy to implement the dynamics in this formalism was presented in our first paper Lanéry and Thiemann (2017) (see also Lanéry, 2016, section 4), which we now test in two simple toy-models. The first one is a very basic linear model, meant as an illustration of the general procedure, and we will only discuss it at the classical level. In the second one, we reformulate the Schrödinger equation, treated as a classical field theory, within this projective framework, and proceed to its (non-relativistic) second quantization. We are then able to reproduce the physical content of the usual Fock quantization.

Active Learning for Automatic Audio Processing of Unwritten Languages (ALAPUL)

DTIC Science & Technology

2016-07-01

AFRL-RH-WP-TR-2016-0074 ACTIVE LEARNING FOR AUTOMATIC AUDIO PROCESSING OF UNWRITTEN LANGUAGES (ALAPUL) Dimitra Vergyri Andreas Kathol Wen Wang...June 2015-July 2016 4. TITLE AND SUBTITLE Active Learning for Automatic Audio Processing of Unwritten Languages (ALAPUL) 5a. CONTRACT NUMBER...5430, 27 October 2016 1. SUMMARY The goal of the project was to investigate development of an automatic spoken language processing (ASLP) system

Acta Aeronautica et Astronautica Sinica,

DTIC Science & Technology

1983-07-28

substructural analysis in modal synthesis - two improved substructural assembling techniques 49 9-node quadrilateral isoparametric element 64 Application of laser...Time from Service Data, J. Aircraft, Vol. 15, No. 11, 1978. 48 MULTI-LEVEL SUBSTRUCTURAL ANALYSIS IN MODAL SYNTHESIS -- TWO IMPROVED SUBSTRUCTURAL...34 Modal Synthesis in Structural Dynamic Analysis ," Naching Institute of Aeronautics and Astronautics, 1979. 62a 8. Chang Te-wen, "Free-Interface Modal

Economic Impacts from Spending by Marina Slip Reenter at Raystown Lake

DTIC Science & Technology

2008-02-01

Impacts from Spending by Marina Slip Renters at Raystown Lake Wen-Huei Chang, Richard Kasul, LiChu Lee, and Kathleen Perales Environmental ...water quality, social or environmental impacts , or the like. This study did not include changes in use based on increases in gasoline prices or...1997. Classifcation of Corps of Engineers Projects for Economic Impact Assesment . Unpublished MS Thesis. East Lansing, MI: Department of Park

Seismic images under the Beijing region inferred from P and PmP data

NASA Astrophysics Data System (ADS)

Lei, Jianshe; Xie, Furen; Lan, Congxin; Xing, Chengqi; Ma, Shizhen

2008-07-01

In this study a new tomographic method is applied to over 1500 high-quality PmP (Moho reflected wave) travel-time data as well as over 38,500 high-quality first P-wave arrivals to determine a detailed 3D crustal velocity structure under Beijing and adjacent areas. Results of detailed resolution analyses show that the PmP data can significantly improve the resolution of the model in the middle and lower crust. After the PmP data are included in the tomographic inversion, our new model not only displays the tectonic feature appeared in the previous studies, but also reveals some new features. The Zhangjiakou-Bohai Sea fault zone (Zhang-Bo zone) is imaged as prominent and continuous low-velocity (low-V) anomalies in the shallower crust, while in the middle and lower crust it shows intermittent low-V anomalies extending down to the uppermost mantle. Furthermore, the pattern of low-V anomalies is different along the Zhang-Bo zone from the southeast to the northwest, indicating that there exist large differences in the dynamic evolution of Taihangshan and Yanshan uplifts and North China depression basin. Prominent low-V anomalies are visible under the source area of the 4 July 2006 Wen-An earthquake (M 5.1), suggesting that the occurrence of the Wen-An earthquake is possibly related to the effect of the crustal fluids probably caused by the upwelling of the hot and wet asthenospheric materials due to the deep dehydration of the stagnant Pacific slab in the mantle transition zone. The fluids in the lower crust may cause the weakening of the seismogenic layer in the upper and middle crust and thus contribute to the initiation of the Wen-An earthquake. This is somewhat similar to the cause of the 1695 Sanhe-Pinggu earthquake and the 1976 Tangshan earthquake in the region, as well as the 1995 Kobe earthquake in Japan and the 2001 Bhuj earthquake in India.

Data Analysis, Modeling, and Ensemble Forecasting to Support NOWCAST and Forecast Activities at the Fallon Naval Station

DTIC Science & Technology

2011-09-30

forecasting and use of satellite data assimilation for model evaluation (Jiang et al, 2011a). He is a task leader on another NSF EPSCoR project...K. Horvath, R. Belu, 2011a: Application of variational data assimilation to dynamical downscaling of regional wind energy resources in the western...1 DISTRIBUTION STATEMENT A. Approved for public release; distribution is unlimited. Data Analysis, Modeling, and Ensemble Forecasting to

CRISPR-Cas Gatekeeper: Slow on the Uptake but Gets the Job Done.

PubMed

Whitaker, Rachel J; Vanderpool, Carin K

2016-02-10

Microbial CRISPR-Cas acts as a defense, but also as a gatekeeper controlling the flow of new genes into microbial genomes. In a recent Cell paper, Jiang et al. (2016) uncover the functional importance of transcription-dependent RNA targeting in type III-A CRISPR-Cas antiviral defense and provide insight into the co-evolution of virus-host symbioses. Copyright © 2016 Elsevier Inc. All rights reserved.

Passive Mode Carbon Nanotube Underwater Acoustic Transducer

DTIC Science & Technology

2016-09-20

Acoustical transducer arrays can reflect a sound signal in reverse to the sender which can be used for echo location devices. [0008] In Jiang...of this layer of the medium determines the amplitude of the resulting sound waves. [0005] Recently, there has been development of underwater...structures. The energy is partially reflected from interfaces between the geologic structure and is detected with geophone or hydrophone sensors

John Turner | NREL

Science.gov Websites

; International Journal of Energy Research 32 (5), 379-407. Ahn, K.S., Shet, S., Deutsch, T., Jiang, C.S., Yan, Y and Sustainable Energy, an AIP journal. Research Interests Dr. Turner has been recognized as a methods, definitions, and reporting protocols." Journal of Materials Research 25 (01), 3-16. Yin, W.J

Reconstructing the spatial pattern of historical forest land in China in the past 300 years

NASA Astrophysics Data System (ADS)

Yang, Xuhong; Jin, Xiaobin; Xiang, Xiaomin; Fan, Yeting; Shan, Wei; Zhou, Yinkang

2018-06-01

The reconstruction of the historical forest spatial distribution is of a great significance to understanding land surface cover in historical periods as well as its climate and ecological effects. Based on the maximum scope of historical forest land before human intervention, the characteristics of human behaviors in farmland reclamation and deforestation for heating and timber, we create a spatial evolution model to reconstruct the spatial pattern of historical forest land. The model integrates the land suitability for reclamation, the difficulty of deforestation, the attractiveness of timber trading markets and the abundance of forest resources to calibrate the potential scope of historical forest land with the rationale that the higher the probability of deforestation for reclamation and wood, the greater the likelihood that the forest land will be deforested. Compared to the satellite-based forest land distribution in 2000, about 78.5% of our reconstructed historical forest grids are of the absolute error between 25% and -25% while as many as 95.85% of those grids are of the absolute error between 50% and -50%, which indirectly validates the feasibility of our reconstructed model. Then, we simulate the spatial distribution of forest land in China in 1661, 1724, 1820, 1887, 1933 and 1952 with the grid resolution of 1 km × 1 km. Our result shows that (1) the reconstructed historical forest land in China in the past 300 years concentrates in DaXingAnLing, XiaoXingAnLing, ChangBaiShan, HengDuanShan, DaBaShan, WuYiShan, DaBieShan, XueFengShang and etc.; (2) in terms of the spatial evolution, historical forest land shrank gradually in LiaoHe plains, SongHuaJiang-NenJiang plains and SanJiang plains of eastnorth of China, Sichuan basins and YunNan-GuiZhou Plateaus; and (3) these observations are consistent to the proceeding of agriculture reclamation in China in past 300 years towards Northeast China and Southwest China.

An ultra low noise telecom wavelength free running single photon detector using negative feedback avalanche diode.

PubMed

Yan, Zhizhong; Hamel, Deny R; Heinrichs, Aimee K; Jiang, Xudong; Itzler, Mark A; Jennewein, Thomas

2012-07-01

It is challenging to implement genuine free running single-photon detectors for the 1550 nm wavelength range with simultaneously high detection efficiency (DE), low dark noise, and good time resolution. We report a novel read out system for the signals from a negative feedback avalanche diode (NFAD) [M. A. Itzler, X. Jiang, B. Nyman, and K. Slomkowski, "Quantum sensing and nanophotonic devices VI," Proc. SPIE 7222, 72221K (2009); X. Jiang, M. A. Itzler, K. ODonnell, M. Entwistle, and K. Slomkowski, "Advanced photon counting techniques V," Proc. SPIE 8033, 80330K (2011); M. A. Itzler, X. Jiang, B. M. Onat, and K. Slomkowski, "Quantum sensing and nanophotonic devices VII," Proc. SPIE 7608, 760829 (2010)], which allows useful operation of these devices at a temperature of 193 K and results in very low darkcounts (∼100 counts per second (CPS)), good time jitter (∼30 ps), and good DE (∼10%). We characterized two NFADs with a time-correlation method using photons generated from weak coherent pulses and photon pairs produced by spontaneous parametric down conversion. The inferred detector efficiencies for both types of photon sources agree with each other. The best noise equivalent power of the device is estimated to be 8.1 × 10(-18) W Hz(-1/2), more than 10 times better than typical InP/InGaAs single photon avalanche diodes (SPADs) show in free running mode. The afterpulsing probability was found to be less than 0.1% per ns at the optimized operating point. In addition, we studied the performance of an entanglement-based quantum key distribution (QKD) using these detectors and develop a model for the quantum bit error rate that incorporates the afterpulsing coefficients. We verified experimentally that using these NFADs it is feasible to implement QKD over 400 km of telecom fiber. Our NFAD photon detector system is very simple, and is well suited for single-photon applications where ultra-low noise and free-running operation is required, and some afterpulsing

Requirements for a network storage service

NASA Technical Reports Server (NTRS)

Kelly, Suzanne M.; Haynes, Rena A.

1992-01-01

Sandia National Laboratories provides a high performance classified computer network as a core capability in support of its mission of nuclear weapons design and engineering, physical sciences research, and energy research and development. The network, locally known as the Internal Secure Network (ISN), was designed in 1989 and comprises multiple distributed local area networks (LAN's) residing in Albuquerque, New Mexico and Livermore, California. The TCP/IP protocol suite is used for inner-node communications. Scientific workstations and mid-range computers, running UNIX-based operating systems, compose most LAN's. One LAN, operated by the Sandia Corporate Computing Directorate, is a general purpose resource providing a supercomputer and a file server to the entire ISN. The current file server on the supercomputer LAN is an implementation of the Common File System (CFS) developed by Los Alamos National Laboratory. Subsequent to the design of the ISN, Sandia reviewed its mass storage requirements and chose to enter into a competitive procurement to replace the existing file server with one more adaptable to a UNIX/TCP/IP environment. The requirements study for the network was the starting point for the requirements study for the new file server. The file server is called the Network Storage Services (NSS) and is requirements are described in this paper. The next section gives an application or functional description of the NSS. The final section adds performance, capacity, and access constraints to the requirements.

The gene expression profile of resistant and susceptible Bombyx mori strains reveals cypovirus-associated variations in host gene transcript levels.

PubMed

Guo, Rui; Wang, Simei; Xue, Renyu; Cao, Guangli; Hu, Xiaolong; Huang, Moli; Zhang, Yangqi; Lu, Yahong; Zhu, Liyuan; Chen, Fei; Liang, Zi; Kuang, Sulan; Gong, Chengliang

2015-06-01

High-throughput paired-end RNA sequencing (RNA-Seq) was performed to investigate the gene expression profile of a susceptible Bombyx mori strain, Lan5, and a resistant B. mori strain, Ou17, which were both orally infected with B. mori cypovirus (BmCPV) in the midgut. There were 330 and 218 up-regulated genes, while there were 147 and 260 down-regulated genes in the Lan5 and Ou17 strains, respectively. Gene ontology (GO) enrichment and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment for differentially expressed genes (DEGs) were carried out. Moreover, gene interaction network (STRING) analyses were performed to analyze the relationships among the shared DEGs. Some of these genes were related and formed a large network, in which the genes for B. mori cuticular protein RR-2 motif 123 (BmCPR123) and the gene for B. mori DNA replication licensing factor Mcm2-like (BmMCM2) were key genes among the common up-regulated DEGs, whereas the gene for B. mori heat shock protein 20.1 (Bmhsp20.1) was the central gene among the shared down-regulated DEGs between Lan5 vs Lan5-CPV and Ou17 vs Ou17-CPV. These findings established a comprehensive database of genes that are differentially expressed in response to BmCPV infection between silkworm strains that differed in resistance to BmCPV and implied that these DEGs might be involved in B. mori immune responses against BmCPV infection.

"Wen the Flood Km We Had to Lv": Children's Understandings of Disaster.

ERIC Educational Resources Information Center

Shreve, Roberta; Danbom, Karen; Hanhan, Sara

2002-01-01

Notes that reflection can support both teachers and students in the aftermath of a disaster. Examines the visual and written works of North Dakota and Minnesota children who were victims of the flooding of the Red River in 1997 as a representational way to gain a broad perspective on children's thinking about their experiences surrounding the…

DynaGuard: Armoring Canary-Based Protections against Brute-Force Attacks

DTIC Science & Technology

2015-12-11

public domain. Non-exclusive copying or redistribution is...sje ng 462 .lib qua ntu m 464 .h2 64r ef 471 .om net pp 473 .as tar 483 .xa lan cbm k Apa che Ng inx Pos tgre SQ L SQ Lite My SQ L Sl ow do w n (n...k 456 .hm me r 458 .sje ng 462 .lib qua ntu m 464 .h2 64r ef 471 .om net pp 473 .as tar 483 .xa lan cbm k Apa che Ng inx Pos tgre SQ L SQ Lite My

Wireless Communications

NASA Astrophysics Data System (ADS)

1991-01-01

A technology utilization project led to the commercial adaptation of a Space Shuttle Orbiter wireless infrared voice communications system. The technology was adapted to a LAN system by Wilton Industries, one of the participants. Because the system is cable-free, installation charges are saved, and it can be used where cable is impractical. Resultant products include the IRplex 6000. Transceivers can be located anywhere and can include mobile receivers. The system provides wireless LAN coverage up to 44,000 square feet. applications include stock exchange communications, trade shows, emergency communications, etc.

Reliability and availability modeling of coupled communication networks - A simplified modeling approach

NASA Technical Reports Server (NTRS)

Shooman, Martin L.; Cortes, Eladio R.

1991-01-01

The network-complexity of LANs and of LANs that are interconnected by bridges and routers poses a challenging reliability-modeling problem. The present effort toward these problems' solution attempts to simplify them by reducing their number of states through truncation and state merging, as suggested by Shooman and Laemmel (1990). Through the use of state merging, it becomes possible to reduce the Bateman-Cortes 161 state model to a two state model with a closed-form solution. In the case of coupled networks, a technique which allows for problem-decomposition must be used.

A New Approach to the Measurement of Educational Outcomes for Institutions of High Learning.

DTIC Science & Technology

1984-12-01

Instructs on four levels of undergraduate education. At the end of that year, students have completed the freshman, sophomore, junior, or senior year. Wen...conclusions for the aggregate model even though individual models are discussed. During any given academic year, the undergraduate university has students ... students quit at every step along the four year university ladder to an undergraduate degree. In other words, the more heterogeneous (as measured by

Predicting Suicide Attacks: Integrating Spatial, Temporal, and Social Features of Terrorist Attack Targets

DTIC Science & Technology

2013-01-01

used in health and criminol- ogy to predict outcomes (Browning, Cagney, and Wen, 2003; Samp- son, Morenoff, and Gannon -Rowley, 2002 ). For each...Bernard, H . Russell , and Gery W. Ryan, Analyzing Qualitative Data: Systematic Approaches, Thousand Oaks, Calif.: Sage, 2010. Berrebi, Claude, “Evidence...PERSON a. REPORT unclassified b . ABSTRACT unclassified c. THIS PAGE unclassified Standard Form 298 (Rev. 8-98) Prescribed by ANSI Std Z39-18

Solidago Virgaurea for Prostate Cancer Therapy

DTIC Science & Technology

2009-04-01

CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT 18 . NUMBER OF PAGES 19a. NAME OF RESPONSIBLE PERSON USAMRMC a. REPORT U b. ABSTRACT U c...Kounosuke Watabe (2008). RhoC promotes metastasis via activation of Pyk2 pathway in prostate cancer. Cancer Res. 68( 18 ):7613-20. 3. Megumi Iiizumi, Wen...effectively blocked tumorigenesis, angiogenesis and metastasis in various mouse xenograft models including pancreatic and gastric cancers [46,49]. Another

China Report: Science and Technology, No. 209. China Addresses Environmental Issues -- 1/83

DTIC Science & Technology

1983-10-12

determines suc- cess or failure of a plan. The steps in planning can be divided into two stages , preparation and planning. The preparation stage ...Noise Control Legislation Requirements Surveyed (Wen Bobing; FAXUE YANJIU, No 6, 1982)........... 21 System of Two -Fines in...with constant improvement in economic results, it is necessary to adopt the two phase strategic plan of laying a good foundation in the first 10 years

Humanized in vivo Model for Autoimmune Diabetes

DTIC Science & Technology

2009-02-01

Manuscripts Gebe JA, Yue BB, Unrath KA, Falk BA, and Nepom GT. Restricted autoantigen recognition associated with deletional and adaptive regulatory...Unrath KA, Falk BA, Ito K, Wen L, Daniels TL, Lernmark A, Nepom GT. Age-dependent loss of tolerance to an immunodominant epitope of glutamic acid...Miyake T, Falk BA, Nepom GT. Autoreactive human T-cell receptor initiates insulitis and impaired glucose tolerance in HLA DR4 transgenic mice. J

Exposure to dim light at night during early development increases adult anxiety-like responses.

PubMed

Borniger, Jeremy C; McHenry, Zachary D; Abi Salloum, Bachir A; Nelson, Randy J

2014-06-22

Early experiences produce effects that may persist throughout life. Therefore, to understand adult phenotype, it is important to investigate the role of early environmental stimuli in adult behavior and health. Artificial light at night (LAN) is an increasingly common phenomenon throughout the world. However, animals, including humans, evolved under dark night conditions. Many studies have revealed affective, immune, and metabolic alterations provoked by aberrant light exposure and subsequent circadian disruption. Pups are receptive to entraining cues from the mother and then light early during development, raising the possibility that the early life light environment may influence subsequent behavior. Thus, to investigate potential influences of early life exposure to LAN on adult phenotype, we exposed mice to dim (~5 lux; full spectrum white light) or dark (~0 lux) nights pre- and/or postnatally. After weaning at 3 weeks of age, all mice were maintained in dark nights until adulthood (9 weeks of age) when behavior was assessed. Mice exposed to dim light in early life increased anxiety-like behavior and fearful responses on the elevated plus maze and passive avoidance tests. These mice also displayed reduced growth rates, which ultimately normalized during adolescence. mRNA expression of brain derived neurotrophic factor (BDNF), a neurotrophin previously linked to early life environment and adult phenotype, was not altered in the prefrontal cortex or hippocampus by early life LAN exposure. Serum corticosterone concentrations were similar between groups at weaning, suggesting that early life LAN does not elicit a long-term physiologic stress response. Dim light exposure did not influence behavior on the open field, novel object, sucrose anhedonia, or forced swim tests. Our data highlight the potential deleterious consequences of low levels of light during early life to development and subsequent behavior. Whether these changes are due to altered maternal behavior

Peng Peiyun and Jiang Zhenghua answer questions raised by both Chinese and foreign journalists.

PubMed

1993-04-01

In April 1993, the Minister and Vice Minister of the Chinese State Family Planning (FP) Commission held a news conference for Chinese and foreign journalists on population and FP. The Chinese FP program has lowered the birth rate by .5% in 5 years, thus adverting 15 million births. A 1992 survey of 385,000 people showed that the number of acceptors increased 12.3% during 1988-92, and unplanned births declined by 54.7% in the same period. Early marriage were 48% less frequent; marriage age increased from 21.8 to 22.5 years. The fertility rate has experienced this rapid decline because efforts were strengthened in the past 2 years. Despite achieving below replacement level fertility, efforts will continue to enact the current FP policy. Whereas the sex ratio is higher than international standards (111.3 vs. 106), China has instituted and publicized laws and incentives designed to improve the status of women and enhance the equality of women. The phenomenon of "converse elimination," which occurs with urban intellectuals being confined to one child, whereas rural inhabitants have more children, is a natural result of the condition of rural life which makes more children necessary because of the practical daily problems rural inhabitants face. China's population policy, however, is designed to stress both population control and improvement of the quality of human resources. The current policy was devised as a response to conditions which are unlikely to change before the year 2000. Rural areas require access to education, health care, and culture. The policy includes the use of incentives and disincentives for Fp workers, and this system is subject to abuse. The objective of the incentives and disincentives is encouraged and citizens have recourse in the courts if officials behave irresponsibly. A more favorable environment for FP will be created as China moves toward a socialist market economy. As labor migration from rural to urban areas increases, however, FP management will have to be combined with employment credentials to monitor possible unplanned births.

Rickettsia parkeri in Gulf Coast Ticks, Southeastern Virginia, USA

DTIC Science & Technology

2011-05-01

Rickettsia parkeri in Gulf Coast Ticks, Southeastern Virginia, USA Chelsea L. Wright, Robyn M. Nadolny, Ju Jiang, Allen L. Richards, Daniel E...Virginia. We found that 43.1% of the adult Gulf Coast ticks collected in the summer of 2010 carried Rickettsia parkeri, suggesting that persons living in...or visiting southeastern Virginia are at risk for infection with this pathogen. Rickettsia parkeri is an obligate intracellular bacterium belonging

Brain-Derived Neurotrophic Factor (BDNF) and Traumatic Brain Injury (Head and Spinal)

DTIC Science & Technology

2000-01-01

phosphatidylinositol 3-kinase are involved in brain-derived neurotrophic factor- mediated survival and neuritogenesis of the neuroblastoma cell line ... SH - SY5Y , J. Neurochem. 73 (1999) 1409-1421. 15. Gottshalk, W.A., Jiang, H., Tartaglia, N., Feng, L., Figurov, A., Lu, B., Signaling mechanisms...NT-6), and neurotrophin-7 (NT-7) (4, 5, 24, 80). Neurotrophins are believed to promote their cell survival, growth, and differentiation effects

China/Taiwan: Evolution of the One China Policy - Key Statements from Washington, Beijing, and Taipei

DTIC Science & Technology

2007-07-09

48 PRC Premier Li Peng Warns Taiwan . . . . . . . . . . . . . . . . . . . . . . . . . 48 Mainland-Taiwan “Koo-Wang...and March 1993, PRC President Jiang Zemin and Premier Li Peng began to warn of having to use “drastic” or “resolute” measures to prevent Taiwan...commitment in its referral to Quemoy and Matsu.” (Wolff and Simon, p. 282-283.) 95 “Ye Jianying Explains Policy Concerning Return of Taiwan to Motherland and

Development of RNAi Libraries for Target Validation and Therapeutics

DTIC Science & Technology

2006-03-01

met using a hammerhead ribozyme transgene reduces in vitro invasion and migration in prostate cancer cells. Prostate, 60: 317-324, 2004. 49...Watkins, G., Mason, M.D., Jiang, W.G. (2004) Targeting the HGF/SF receptor c-met using a hammerhead ribozyme transgene reduces in vitro invasion...reduction of tumor growth (27). In addition, when c-met was knocked-down using ribozymes , cell invasion and metastasis were inhibited both in vitro

Optimal Mass Transport for Statistical Estimation, Image Analysis, Information Geometry, and Control

DTIC Science & Technology

2017-01-10

Metric Uncertainty for Spectral Estimation based on Nevanlinna-Pick Interpolation, (with J. Karlsson) Intern. Symp. on the Math . Theory of Networks and...Systems, Melbourne 2012. 22. Geometric tools for the estimation of structured covariances, (with L. Ning, X. Jiang) Intern. Symposium on the Math . Theory...estimation and the reversibility of stochastic processes, (with Y. Chen, J. Karlsson) Proc. Int. Symp. on Math . Theory of Networks and Syst., July

Alluvial Fan, China

NASA Image and Video Library

2010-03-03

Image taken 5/2/2002 by ASTER: A vast alluvial fan blossoms across the desolate landscape between the Kunlun and Altun mountain ranges that form the southern border of the Taklimakan Desert in China's XinJiang Province. This image can be found on ASTER Path 143 Row 34, center: 37.43 N, 84.30 E. To learn more about the Landsat satellite go to: landsat.gsfc.nasa.gov/

Utilizing the Power of Nanostructures to Their Fullest Capability in Energetic Formulations

DTIC Science & Technology

2016-02-01

aluminum-cyclopentadienyl clusters. J Phys Chem A. 2011;115(48):14100– 14109. Zeng Q, Jiang X, Yu A, Lu G. Growth mechanisms of silver nanoparticles : a...assemblies of gas generators containing nanoscale Al (conventional Al nanoparticles and Al nanoclusters) to overcome the sintering and/or oxide-formation...issues. Experimentally, a previously published hypothesis for the mechanism leading to enhanced energy release from Al nanoparticles in the presence of

Identification and Mapping of Mechanically Exfoliated 1H-MoS2 Flakes for Field-Effect Transistors

DTIC Science & Technology

2014-08-01

structures directly onto 1H- and 2H-MoS2. A methyl methacrylate (MMA) and polymethyl methacrylate ( PMMA ) bilayer resist process will be used for all...the fiscal year. 9 5. References 1. Novoselov KS, Geim AK, Morozov SV, Jiang D, Zhang Y, Dubonos SV, Grigorieva IV, Firsov AA . Electric...photoluminescence PMMA polymethyl methacrylate TMDs transition metal dichalcogenides 12 1 DEFENSE TECH INFO CTR (PDF) ATTN DTIC OCA (PDF) 2

A Study on Run Time Assurance for Complex Cyber Physical Systems

DTIC Science & Technology

2013-04-18

safety verification approach was applied to synchronization of distributed local clocks of the nodes on a CAN bus by Jiang et al. [36]. The class of...mode of interaction between the instrumented system and the checker, we distin- guish between synchronous and asynchronous monitoring. In synchronous ...occurred. Synchronous monitoring may deliver a higher degree of assurance than the asynchronous one, because it can block a dangerous action. However

Hypersonic Transition Along Curved Surfaces in the Presence of Vortices and Their Control by Using Microtextured Surfaces

DTIC Science & Technology

2015-05-13

Bhagwandin, Pierre N. Floriano, Nico- laos Christodoulides, and John T. McDevitt, “Programmable nano- bio -chip sensors : Analytical meets clinical”, Analytical...superhydrophobic surfaces can be used in many technologies such as self-cleaning coatings for satellite dishes, solar energy panels, photovoltaics and...Design of hydrophobic surfaces for liquid droplet control”, NPG Asia Mater. 3, pp. 49–56 (2011). [15] K. Liu and L. Jiang, “ Bio -inspired self-cleaning

JPRS Report, Science & Technology, China

DTIC Science & Technology

1992-10-09

the nation’s first inert gas evaporation apparatus for fabrication of nanoparticles and have fabricated bulk test samples of nanostructures via...CAS researchers have employed chemical techniques to fabricate A1203 nanoparticles and bulk structures in the 8-10-nm range, with controllable vari...ability of nanoparticle size. CAS Beijing Vacuum Physics Laboratory 92P60435B Shanghai JIEFANG RIBAO in Chinese 17 Aug 92 p 3 [Article by Jiang

Time and Frequency Activities at The U.S. Naval Observatory

DTIC Science & Technology

2011-01-01

TWSTFT ) The most accurate means of operational long-distance time transfer is generally believed to be TWSTT [15-18], although the most precise...Frequency Transfer ( TWSTFT ),” Review of Radio Science (Oxford Science Publications), pp. 27-44. [16] L. A. Breakiron, A. L. Smith, B. C. Fonville...Matsakis, L. Breakiron, A. Bauch, D. Piester, D., and Z. Jiang, 2009, “Two-Way Satellite Time and Frequency ( TWSTFT ) Transfer Calibration Constancy from

Time and Frequency Activities at the U.S. Naval Observatory

DTIC Science & Technology

2010-01-01

TWSTT, ALSO REFERRED TO AS TWO-WAY SATELLITE TIME AND FREQUENCY TRANSFER ( TWSTFT ) The most accurate means of operational long-distance time...Frequency Transfer ( TWSTFT ),” Review of Radio Science (Oxford Science Publications), pp. 27-44. [25] L. A. Breakiron, A. L. Smith, B. C. Fonville, E...Breakiron, A. Bauch, D. Piester, D., and Z. Jiang, 2009, “Two-Way Satellite Time and Frequency ( TWSTFT ) Transfer Calibration Constancy from Closure

New Forms of Matter in Optical Lattices

DTIC Science & Technology

2016-05-19

Daley, A. M. Läuchli, and P. Zoller Thermal vs. Entanglement Entropy: A Measurement Protocol for Fermionic Atoms with a Quantum Gas Microscope...J. A. Edge, E. Taylor, S. Zhang, S. Trotzky, J. H. Thywissen Transverse Demagnetization Dynamics of a Unitary Fermi Gas Science 344, 722 (2014...Jiang, J Ignacio Cirac, Peter Zoller, Mikhail D Lukin, "Topologically Protected Quantum State Transfer in a Chiral Spin Liquid , "Nature Communications

China Report: Political, Sociological and Military Affairs.

DTIC Science & Technology

1985-07-31

his party at the Jingjiang hotel yesterday. Comrade Jiang Zemin, deputy chief of the State Council’s leading group for invigorating the electronics... industry and former minister of electronics industry , attended the meeting and banquet. The delegation of the GDR Ministry of Electrical Engineering...and Electronics arrived in Shanghai on 24 June in the company of Comrade Xie Gaojue, vice minister of electronics industry . Comrade Felix Meier and

DOE Office of Scientific and Technical Information (OSTI.GOV)

Blume-Kohout, Robin J; Scholten, Travis L.

Quantum state tomography on a d-dimensional system demands resources that grow rapidly with d. They may be reduced by using model selection to tailor the number of parameters in the model (i.e., the size of the density matrix). Most model selection methods typically rely on a test statistic and a null theory that describes its behavior when two models are equally good. Here, we consider the loglikelihood ratio. Because of the positivity constraint ρ ≥ 0, quantum state space does not generally satisfy local asymptotic normality (LAN), meaning the classical null theory for the loglikelihood ratio (the Wilks theorem) shouldmore » not be used. Thus, understanding and quantifying how positivity affects the null behavior of this test statistic is necessary for its use in model selection for state tomography. We define a new generalization of LAN, metric-projected LAN, show that quantum state space satisfies it, and derive a replacement for the Wilks theorem. In addition to enabling reliable model selection, our results shed more light on the qualitative effects of the positivity constraint on state tomography.« less

Behavior of the maximum likelihood in quantum state tomography

DOE PAGES

Blume-Kohout, Robin J; Scholten, Travis L.

2018-02-22

Quantum state tomography on a d-dimensional system demands resources that grow rapidly with d. They may be reduced by using model selection to tailor the number of parameters in the model (i.e., the size of the density matrix). Most model selection methods typically rely on a test statistic and a null theory that describes its behavior when two models are equally good. Here, we consider the loglikelihood ratio. Because of the positivity constraint ρ ≥ 0, quantum state space does not generally satisfy local asymptotic normality (LAN), meaning the classical null theory for the loglikelihood ratio (the Wilks theorem) shouldmore » not be used. Thus, understanding and quantifying how positivity affects the null behavior of this test statistic is necessary for its use in model selection for state tomography. We define a new generalization of LAN, metric-projected LAN, show that quantum state space satisfies it, and derive a replacement for the Wilks theorem. In addition to enabling reliable model selection, our results shed more light on the qualitative effects of the positivity constraint on state tomography.« less

Effect of Citrus bergamia juice on human neuroblastoma cells in vitro and in metastatic xenograft models.

PubMed

Navarra, M; Ursino, M R; Ferlazzo, N; Russo, M; Schumacher, U; Valentiner, U

2014-06-01

Neuroblastoma is the most common extracranial pediatric solid tumor with poor prognosis in children with disseminated stage of disease. A number of studies show that molecules largely distributed in commonly consumed fruits and vegetables may have anti-tumor activity. In this study we evaluate the effect of Citrus bergamia (bergamot) juice (BJ) in vitro and in a spontaneous metastatic neuroblastoma SCID mouse model. Qualitative and quantitative characterizations of BJ flavonoid fractions were performed by RP-HPLC/PDA/MS. We show that BJ significantly affects SK-N-SH and LAN-1 cell proliferation in vitro, but fails to reduce primary tumor weight in vivo. Moreover, BJ reduced cell adhesiveness and invasion of LAN-1 and SK-N-SH cells in vitro and the number of pulmonary metastases under consideration of the number of tumor cells in the blood in mice inoculated with LAN-1 cells in vivo. These effects without any apparent sign of systemic toxicity confirm the potential clinical interest of BJ and lay the basis for further investigation in cancer. Copyright © 2014. Published by Elsevier B.V.

Behavior of the maximum likelihood in quantum state tomography

DOE Office of Scientific and Technical Information (OSTI.GOV)

Blume-Kohout, Robin J; Scholten, Travis L.

Quantum state tomography on a d-dimensional system demands resources that grow rapidly with d. They may be reduced by using model selection to tailor the number of parameters in the model (i.e., the size of the density matrix). Most model selection methods typically rely on a test statistic and a null theory that describes its behavior when two models are equally good. Here, we consider the loglikelihood ratio. Because of the positivity constraint ρ ≥ 0, quantum state space does not generally satisfy local asymptotic normality (LAN), meaning the classical null theory for the loglikelihood ratio (the Wilks theorem) shouldmore » not be used. Thus, understanding and quantifying how positivity affects the null behavior of this test statistic is necessary for its use in model selection for state tomography. We define a new generalization of LAN, metric-projected LAN, show that quantum state space satisfies it, and derive a replacement for the Wilks theorem. In addition to enabling reliable model selection, our results shed more light on the qualitative effects of the positivity constraint on state tomography.« less

Behavior of the maximum likelihood in quantum state tomography

NASA Astrophysics Data System (ADS)

Scholten, Travis L.; Blume-Kohout, Robin

2018-02-01

Quantum state tomography on a d-dimensional system demands resources that grow rapidly with d. They may be reduced by using model selection to tailor the number of parameters in the model (i.e., the size of the density matrix). Most model selection methods typically rely on a test statistic and a null theory that describes its behavior when two models are equally good. Here, we consider the loglikelihood ratio. Because of the positivity constraint ρ ≥ 0, quantum state space does not generally satisfy local asymptotic normality (LAN), meaning the classical null theory for the loglikelihood ratio (the Wilks theorem) should not be used. Thus, understanding and quantifying how positivity affects the null behavior of this test statistic is necessary for its use in model selection for state tomography. We define a new generalization of LAN, metric-projected LAN, show that quantum state space satisfies it, and derive a replacement for the Wilks theorem. In addition to enabling reliable model selection, our results shed more light on the qualitative effects of the positivity constraint on state tomography.

Discrimination of magnoliae officinalis cortex based on the quantitative profiles of magnolosides by two-channel liquid chromatography with electrochemical detection.

PubMed

Xue, Zhenzhen; Kotani, Akira; Yang, Bin; Hakamata, Hideki

2018-05-31

A two-channel liquid chromatography with electrochemical detection system (2LC-ECD) was newly designed for the simultaneous determination of magnolosides A, B, F, H, and L in the first channel and other magnolosides D and M in the second channel, respectively. Peak heights had linear relationships to the magnoloside concentrations in a range of 0.02-16 μmol/L for H, 0.01-12 μmol/L for A, 0.02-12 μmol/L for F and L, 0.01-8 μmol/L for B, 0.002-6 μmol/L for D, and 0.002-4 μmol/L for M, respectively. Seven magnolosides in magnoliae officinalis cortex (MOC) were determined by the 2LC-ECD, and the obtained quantitative profiles of magnolosides were applied to the discrimination between the MOC samples harvested from Hubei and Sichuan (called Chuan po) and from Zhejiang and Fujian (called Wen po). By principal component analysis (PCA) and supervised partial least squares discriminant analysis (PLS-DA) based on the quantitative profiles of the magnolosides, Chuan po were clearly discriminated from Wen po on the plots obtained from our multivariable analyses. Copyright © 2018 Elsevier B.V. All rights reserved.

The Virtual Dollhouse: Body Image and Weight Stigma in Second Life

NASA Astrophysics Data System (ADS)

Linares, R.; Bailenson, J.; Bailey, J.; Stevenson Won, A.

2012-12-01

Second Life is a virtual world where fantasy and reality collide as users can customize their digital representation or avatar. The act of wanting to ignore or avoid the real world's physical limitations can be called "avatar escapism" (Ducheneaut, Wen, Yee, Wadley, 2009). In the media the increasingly thin standard of beauty (Berel, Irving, 1998) has augmented negative stereotypes of overweight people to the point of making it acceptable for people to ridicule others' bodies image (Wang, Brownell, Wadden, 2004). In the real world, these concepts hurt people who are unable or unwilling to achieve an "acceptable" body size often leading them to be ridiculed. In the virtual world, a person may portray their desired body potentially escaping judgment from others. Can this more liberated form of bodily expression lead people to expect and need that perfection to a point where they abandon the real world in order to live in that perfection? With this knowledge we looked at the implications of the real world idolization of the perfect body and how this is transferred into the virtual space. In addition, we investigated how the reactions and behaviors that people have when others rebel against the "Barbie doll" appearance (Ducheneaut, Wen, Yee, Wadley, 2009) affect us in the real world.

Cooking Coal Use and All-Cause and Cause-Specific Mortality in a Prospective Cohort Study of Women in Shanghai, China.

PubMed

Kim, Christopher; Seow, Wei Jie; Shu, Xiao-Ou; Bassig, Bryan A; Rothman, Nathaniel; Chen, Bingshu E; Xiang, Yong-Bing; Hosgood, H Dean; Ji, Bu-Tian; Hu, Wei; Wen, Cuiju; Chow, Wong-Ho; Cai, Qiuyin; Yang, Gong; Gao, Yu-Tang; Zheng, Wei; Lan, Qing

2016-09-01

Nearly 4.3 million deaths worldwide were attributable to exposure to household air pollution in 2012. However, household coal use remains widespread. We investigated the association of cooking coal and all-cause and cause-specific mortality in a prospective cohort of primarily never-smoking women in Shanghai, China. A cohort of 74,941 women were followed from 1996 through 2009 with annual linkage to the Shanghai vital statistics database. Cause-specific mortality was identified through 2009. Use of household coal for cooking was assessed through a residential history questionnaire. Cox proportional hazards models estimated the risk of mortality associated with household coal use. In this cohort, 63% of the women ever used coal (n = 46,287). Compared with never coal use, ever use of coal was associated with mortality from all causes [hazard ratio (HR) = 1.12; 95% confidence interval (CI): 1.05, 1.21], cancer (HR = 1.14; 95% CI: 1.03, 1.27), and ischemic heart disease (overall HR = 1.61; 95% CI: 1.14, 2.27; HR for myocardial infarction specifically = 1.80; 95% CI: 1.16, 2.79). The risk of cardiovascular mortality increased with increasing duration of coal use, compared with the risk in never users. The association between coal use and ischemic heart disease mortality diminished with increasing years since cessation of coal use. Evidence from this study suggests that past use of coal among women in Shanghai is associated with excess all-cause mortality, and from cardiovascular diseases in particular. The decreasing association with cardiovascular mortality as the time since last use of coal increased emphasizes the importance of reducing use of household coal where use is still widespread. Kim C, Seow WJ, Shu XO, Bassig BA, Rothman N, Chen BE, Xiang YB, Hosgood HD III, Ji BT, Hu W, Wen C, Chow WH, Cai Q, Yang G, Gao YT, Zheng W, Lan Q. 2016. Cooking coal use and all-cause and cause-specific mortality in a prospective cohort study of women in Shanghai, China. Environ

Cooking Coal Use and All-Cause and Cause-Specific Mortality in a Prospective Cohort Study of Women in Shanghai, China

PubMed Central

Kim, Christopher; Seow, Wei Jie; Shu, Xiao-Ou; Bassig, Bryan A.; Rothman, Nathaniel; Chen, Bingshu E.; Xiang, Yong-Bing; Hosgood, H. Dean; Ji, Bu-Tian; Hu, Wei; Wen, Cuiju; Chow, Wong-Ho; Cai, Qiuyin; Yang, Gong; Gao, Yu-Tang; Zheng, Wei; Lan, Qing

2016-01-01

Background: Nearly 4.3 million deaths worldwide were attributable to exposure to household air pollution in 2012. However, household coal use remains widespread. Objectives: We investigated the association of cooking coal and all-cause and cause-specific mortality in a prospective cohort of primarily never-smoking women in Shanghai, China. Methods: A cohort of 74,941 women were followed from 1996 through 2009 with annual linkage to the Shanghai vital statistics database. Cause-specific mortality was identified through 2009. Use of household coal for cooking was assessed through a residential history questionnaire. Cox proportional hazards models estimated the risk of mortality associated with household coal use. Results: In this cohort, 63% of the women ever used coal (n = 46,287). Compared with never coal use, ever use of coal was associated with mortality from all causes [hazard ratio (HR) = 1.12; 95% confidence interval (CI): 1.05, 1.21], cancer (HR = 1.14; 95% CI: 1.03, 1.27), and ischemic heart disease (overall HR = 1.61; 95% CI: 1.14, 2.27; HR for myocardial infarction specifically = 1.80; 95% CI: 1.16, 2.79). The risk of cardiovascular mortality increased with increasing duration of coal use, compared with the risk in never users. The association between coal use and ischemic heart disease mortality diminished with increasing years since cessation of coal use. Conclusions: Evidence from this study suggests that past use of coal among women in Shanghai is associated with excess all-cause mortality, and from cardiovascular diseases in particular. The decreasing association with cardiovascular mortality as the time since last use of coal increased emphasizes the importance of reducing use of household coal where use is still widespread. Citation: Kim C, Seow WJ, Shu XO, Bassig BA, Rothman N, Chen BE, Xiang YB, Hosgood HD III, Ji BT, Hu W, Wen C, Chow WH, Cai Q, Yang G, Gao YT, Zheng W, Lan Q. 2016. Cooking coal use and all-cause and cause-specific mortality in

Optimising LAN access to grid enabled storage elements

NASA Astrophysics Data System (ADS)

Stewart, G. A.; Cowan, G. A.; Dunne, B.; Elwell, A.; Millar, A. P.

2008-07-01

When operational, the Large Hadron Collider experiments at CERN will collect tens of petabytes of physics data per year. The worldwide LHC computing grid (WLCG) will distribute this data to over two hundred Tier-1 and Tier-2 computing centres, enabling particle physicists around the globe to access the data for analysis. Although different middleware solutions exist for effective management of storage systems at collaborating institutes, the patterns of access envisaged for Tier-2s fall into two distinct categories. The first involves bulk transfer of data between different Grid storage elements using protocols such as GridFTP. This data movement will principally involve writing ESD and AOD files into Tier-2 storage. Secondly, once datasets are stored at a Tier-2, physics analysis jobs will read the data from the local SE. Such jobs require a POSIX-like interface to the storage so that individual physics events can be extracted. In this paper we consider the performance of POSIX-like access to files held in Disk Pool Manager (DPM) storage elements, a popular lightweight SRM storage manager from EGEE.

Finding topological center of a geographic space via road network

NASA Astrophysics Data System (ADS)

Gao, Liang; Miao, Yanan; Qin, Yuhao; Zhao, Xiaomei; Gao, Zi-You

2015-02-01

Previous studies show that the center of a geographic space is of great importance in urban and regional studies, including study of population distribution, urban growth modeling, and scaling properties of urban systems, etc. But how to well define and how to efficiently extract the center of a geographic space are still largely unknown. Recently, Jiang et al. have presented a definition of topological center by their block detection (BD) algorithm. Despite the fact that they first introduced the definition and discovered the 'true center', in human minds, their algorithm left several redundancies in its traversal process. Here, we propose an alternative road-cycle detection (RCD) algorithm to find the topological center, which extracts the outmost road-cycle recursively. To foster the application of the topological center in related research fields, we first reproduce the BD algorithm in Python (pyBD), then implement the RCD algorithm in two ways: the ArcPy implementation (arcRCD) and the Python implementation (pyRCD). After the experiments on twenty-four typical road networks, we find that the results of our RCD algorithm are consistent with those of Jiang's BD algorithm. We also find that the RCD algorithm is at least seven times more efficient than the BD algorithm on all the ten typical road networks.

[The different experession of human papilloma viral types 6 and 11 in Uyghur and Chinese juvenile recurrent respiratory papillomatosis in a large pediatric population in Xinjiang].

PubMed

Zainura, Amrulla; Yalkun, Yasin; Wu, Mei

2013-11-01

To investigate the Human papilloma viral types 6 and 11 in a large pediatric population in XinJiang and the different expression in chinese and uyghur pediatric population. Using polymerase chain reaction (PCR), we analyzed paraffin embedded tissue in 42 cases of juvenile Recurrent Respiratory Papillomatosis (JRRP)and determined the HPV types 6 and 11, and to correlate these results with retrospectively analysis about those cases who were consecutively treated in our ENT department, meanwhile we carry out a critical review of the literature of JRRP. A total HPV infection positive rate was 97.61% (41/42), and HPV11 positive rate was 63.41% (41/26), HPV6 positive rate was 36.58% (41/15). In uyghur patient HPV11 positive rate was 65.38% (17/26), HPV6 positive rate was53. 33% (8/15). in Chince patient HPV11 positive rate was 34.61% (9/26), HPV6 positive rate was 46.67% (7/15). Juvenile laryngeal papilloma is associated with HPV11, HPV6 infection and we considered that HPV11 infection may be the important guideline of the evaluation of disease prognosis. but no statistical signtificance was determined in the patients of various ethnic groups in Xin jiang (P > 0.05).

Changing the culture of academic medicine: the C-Change learning action network and its impact at participating medical schools.

PubMed

Krupat, Edward; Pololi, Linda; Schnell, Eugene R; Kern, David E

2013-09-01

The culture of academic medicine has been described as hierarchical, competitive, and not highly supportive of female or minority faculty. In response to this, the authors designed the Learning Action Network (LAN), which was part of the National Initiative on Gender, Culture and Leadership in Medicine (C-Change). The LAN is a five-school consortium aimed at changing the organizational culture of its constituent institutions. The authors selected LAN schools to be geographically diverse and representative of U.S. medical schools. Institutional leaders and faculty representatives from constituent schools met twice yearly for four years (2006-2010), forming a cross-institutional learning community. Through their quarterly listing of institutional activities, schools reported a wide array of actions. Most common were increased faculty development and/or mentoring, new approaches to communication, and adoption of new policies and procedures. Other categories included data collection/management, engagement of key stakeholders, education regarding gender/diversity, and new/expanded leadership positions. Through exit interviews, most participants reported feeling optimistic about maintaining the momentum of change. However, some, especially in schools with leadership changes, expressed uncertainty. Participants reported that they felt that the LAN enabled, empowered, facilitated, and/or caused the reported actions.For others who might want to work toward changing the culture of academic medicine, the authors offer several lessons learned from their experiences with C-Change. Most notably, people, structures, policies, and reward systems must be put into place to support cultural values, and broad-based support should be created in order for changes to persist when inevitable transitions in leadership occur.

Histological analysis of the aortic nerve in the rat raised in space (Rapid communication on Neurolab Project).

PubMed

Yamasaki, M; Shimizu, T; Miyake, M; Miyamoto, Y; Waki, H; Katsuda, S I; Oishi, H; Nagayama, T; Katahira, K; Wago, H; Okochi, T; Kaneko, M; Matsumoto, S; Mukai, C; Nagaoka, S; Izumi, T; Yanagawa, K; Uemura, M; O-ishi, H

1998-11-01

To study development of the aortic nerve baroreflex under conditions of microgravity, we examined the cross section of the left aortic nerve (LAN), which is the afferent of the baroreflex, in the neonate rats aged 25 days raised in microgravity on the space shuttle Columbia (flight:FLT group) for 16 days. In this paper, we report a part of the result obtained from the data of the myelinated fibers of LAN analyzed with an electron microscope. Two kind of ground control groups were compared to the FLT group; one was asynchronous ground control (AGC) group where the rats were housed in the same cage as that on the shuttle, and the other was vivarium(VIV) group where the rats were housed in a commercial cage. The LANs in each group were extirpated the from rats perfused with a fixative and embedded for histological analysis. We observed the transverse sections of LAN and took pictures of several areas (magnified to x 2K to x 200K). No irregular myelination was found in all fibers of FLT group when they were compared with two control groups. The thickness of myelin of the maximally myelinated fibers were 0.55 +/- 0.17 micrometer in FLT(n=5), 0.45 +/- 0.10 micrometer in AGC(n=5), and O.47 +/- 0.06 micrometer meter in VIV(n=5). There was no significant difference among three groups (unpared t-test). The results suggest that there is no effect of space environment on the myelin formation of each nerve fiber in the aortic nerve.

Examination of the melatonin hypothesis in women exposed at night to EMF or bright light.

PubMed

Graham, C; Cook, M R; Gerkovich, M M; Sastre, A

2001-05-01

It has been hypothesized that the increased incidence of breast cancer in industrial societies is related to greater exposure to power-frequency electric and magnetic fields (EMF) and/or the presence of high levels of light at night (LAN). EMF and LAN are said to reduce circulating levels of the hormone melatonin which, in turn, allows estrogen levels to rise and stimulate the turnover of breast epithelial stem cells and increase the risk for malignant transformation. Three laboratory-based studies, in which a total of 53 healthy young women were exposed at night to EMF or to LAN under controlled exposure conditions, were performed to determine whether such exposures reduce melatonin and are associated with further alterations in estrogen. All-night exposure to industrial-strength magnetic fields (60 Hz, 28.3 microT) had no effect on the blood levels of melatonin or estradiol. In contrast, nocturnal melatonin levels were profoundly suppressed, and the time of peak concentration was significantly delayed in women exposed to LAN, regardless of whether they were in the follicular or luteal phase of the menstrual cycle. These changes, however, were not associated with alterations in point-for-point matching measures of estradiol. Women who chronically secrete high or low amounts of melatonin each night (area-under-curve range: 86-1,296 pg/mL) also did not differ in their blood levels of estradiol. Taken together, these results are consistent with a growing body of evidence which generally suggests that environmental EMF exposure has little or no effect on the parameters measured in this report.

International Illegal Trade in Wildlife: Threats and U.S. Policy

DTIC Science & Technology

2008-08-22

fact_sheets/ASEAN_WEN .pdf]. 6 House Committee on Natural Resources, “ Poaching American Security: Impacts of Illegal Wildlife Trade,” Hearing, March 5, 2008...Department of State. reportedly sponsoring elephant and rhino poaching for profit, according to several news articles.103 CRS-23 Sources: For “Potential...at the border.134 CRS-34 135 See for example, testimony by Claudia A. McMurray, House Natural Resources Committee, “ Poaching American Security: Impact

Myeloid-Derived Suppressor Cells Prevent Type 1 Diabetes in Murine Models

DTIC Science & Technology

2010-11-01

participating in anti-CD28- mediated tolerance in allo-kidney transplantation ( 15), and ame- lioration of symptoms in the inflammatory bowel disease ...Zhou,* George X. Wang,* Celia M. Divino/ Sofia Casares,§ Shu-Hsia Chen,*’, Wen-Chin Yang/’* and Ping-Ying Pan* Effective immunotherapy for type 1...cell-based tolerogenic therapy in the control of TID and other autoimmune diseases . The Journal of Immunology, 2010, 185: 5828-5834. T ype I

JPRS Report, China

DTIC Science & Technology

1993-05-06

TAIWAN New KMT Pursues Political Struggle [ HSIN HSIN WEN 6 Mar] 64 HONG KONG, MACAO Newly Elected Local Members of CPPCC Published [MING PAO 20...impartially enforcing them will it be possible to attract more foreign investors. Indeed, some foreign business people said: Today you turn your laws and...difficulties. As for the difficulties we mention here, we do not mean a difficulty in making tax pay- ments. When you encounter temporary difficulties, we

Unit Level Variations And Peer Influences In Mental Health Diagnoses In The U.S. Army

DTIC Science & Technology

2017-12-01

INFLUENCES IN MENTAL HEALTH DIAGNOSES IN THE U.S. ARMY by Zhi Wen Tan Kian Wee Evwin Lee December 2017 Thesis Advisor: Yu-Chu Shen Co-Advisor...DATES COVERED Master’s thesis 4. TITLE AND SUBTITLE UNIT-LEVEL VARIATIONS AND PEER INFLUENCES IN MENTAL HEALTH DIAGNOSES IN THE U.S. ARMY 5... health care system, to examine how unit-level variations in incidents of mental health diagnoses affect the likelihood of an individual developing

NATIONAL SECURITY: Relief, Rebukes Follow Agreement on Lee.

PubMed

Lawler, A

2000-09-15

What began as an explosive case of alleged nuclear espionage is expected to end quietly soon when physicist Wen Ho Lee walks free from an Albuquerque, New Mexico, courtroom after 9 months in jail. The ignominious collapse of the government's case and Lee's release have embarrassed federal prosecutors. However, the news was a relief to Asian-American researchers and others who say Lee's status as a suspect had heightened racial tensions at the national labs.

Testing of DentStat (trademark) and Competing Dental Materials

DTIC Science & Technology

2014-06-13

NAVAL MEDICAL RESEARCH UNIT SAN ANTONIO TESTING OF DENTST AT™ AND COMPETING DENTAL MATERIALS Y OON HWANG PHD, JONATHAN STAHL DDS PHD, WAYNE M. D...LtCOL Wen Lien of the US Air Force Dental Evaluation and Consultation Service for assistance with the strength testing. 1 Reviewed and Approved by...direct dental repair materials. They are made of calcium or strontium aluminofluoro-silicate glass powder (base) combined with a water-soluble polymer

Investigation of the Role of the Mitogenic Neuropeptide Galanin in Mammary Gland Development and Carcinogenesis

DTIC Science & Technology

2002-08-01

Nelson Horseman for the lymphocytes. Cell 68:869-877. donation of mice, use of facilities, and fruitful discus- Normanno N, Kim N, Wen D, Smith K, Harris...Development 126:335-344. Biol 210:96-106. Vomachka AJ, Pratt SL, Lockefeer JA, Horseman ND. 2000. Prolactin Brisken C, Heineman A, Chavarria T, Elenbaas...components of the prolactin signalling cascade have demonstrated the importance of this pathway in mammopoiesis and lactation ( Horseman et al., 1997; Liu

Southeast Asian ticks (Acari: Ixodida): a Historical Perspective

DTIC Science & Technology

2007-01-01

Babesia (Luo et al. 2002), Ehrlichia (Wen et al. 2002), Rickettsia (Hirunkanokpun et al. 2003), and Theileria (Sarataphan et al. 1999; Chansiri and...Sarataphan N (2002) Molecular phylogenetic study of Theileria sp. (Thung Song) based on the thymidylate synthetase gene. Parasitol Res 88:S33–S35...Chansiri K, Kawazu S, Kamio T, Tereda Y, Fujisaki K, Philippe H, Sarataphan N (1999) Molecular phylogenetic studies on Theileria parasites based on small

Handbook of Veterinary Claims.

DTIC Science & Technology

1983-03-01

290.1). I will be glad to go over this report in detail with you if there are any questions that need clearing up. WILLIAM G. JACKSON JR . 2 Atch... obstruction occurs with more acute signs related to rupture of the small intestine, followed soon by death due to endotoxic shock and peritonitis when...approved for publication. WILLIAM E. MABSON, Colonel, USAF, BSC Commander UNCLASSIFIED SECURITY CLASSIFICATION OF THIS PAGE (Wen De.Entered), REPORT

Targeting Signal Transducers and Activators of Transcription-3 (Stat3) As a Novel Strategy In Sensitizing Breast Cancer To Egfr-Targeted Therapy

DTIC Science & Technology

2008-06-01

Distribution Unlimited The views, opinions and/or findings contained in this report are those of the author( s ) and...Novel Strategy In Sensitizing Breast Cancer To Egfr-Targeted Therapy 5b. GRANT NUMBER W81XWH-07-1-0390 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR( S ...Hui-Wen Lo, Ph.D. 5d. PROJECT NUMBER 5e. TASK NUMBER Email: huiwen.lo@duke.edu 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME( S

Drosophila as a Screening Platform for Novel Lung Cancer Therapeutics

DTIC Science & Technology

2016-09-01

CoA reductase, an activity that has proven useful clinically for lowering cholesterol (Figure 5A). Two additional statins, atorvastatin and simvastatin...prenylation, are inhibited by GGTI and FTI. Inhibitors are listed in red. (B) Two additional statins, atorvastatin (p % 0.05) and simvastatin (p% 0.05...H., Hou, J., Zhang, X., Zhang, C., Yue, L., Wen, X., Liu, D., Shi, H., Yuan, J., et al. (2013). Atorvastatin overcomes gefitinib resistance in KRAS

China’s Future Nuclear Submarine Force. Insights from Chinese Writings

DTIC Science & Technology

2007-01-01

ts056058.pdf. 115. , , [Lu Jiaben, Wang Shen- glong, Liu Wen, et al.], “‘ ’ ” [Evaluation of Health Protective Effects of “Silver Ginseng ...Based on his instructions, in the course of developing nuclear-powered submarines, we formed a seamless and effective nuclear safety mechanism by...the manner in which France strives to maximize the effectiveness of its second-tier nuclear submarine force.32 The September 2005 issue of (Naval

Humanized in vivo Model for Autoimmune Diabetes

DTIC Science & Technology

2010-05-07

the tolerance mechanisms of high and low avidity T cells reactive to the diabetes autoantigen glutamic acid decarboxylase 65 (GAD65) and their...of this study, we have used humanized DR0401 (DR4) mice and demonstrated that: high avidity T cells reactive to glutamic acid decarboxylase 65...JA, Unrath KA, Falk BA, Ito K, Wen L, Daniels LT, Lernmark A, Nepom GT. Age-dependent loss of tolerance to an immunodominant epitope of glutamic acid

Switch configuration for migration to optical fiber network

NASA Technical Reports Server (NTRS)

Zobrist, George W.

1993-01-01

The purpose is to investigate the migration of an Ethernet LAN segment to fiber optics. At the present time it is proposed to support a Fiber Distributed Data Interface (FDDI) backbone and to upgrade the VAX cluster to fiber optic interface. Possibly some workstations will have an FDDI interface. The remaining stations on the Ethernet LAN will be segmented. The rationale for migrating from the present Ethernet configuration to a fiber optic backbone is due to the increase in the number of workstations and the movement of applications to a windowing environment, extensive document transfers, and compute intensive applications.

Management of the Space Station Freedom onboard local area network

NASA Technical Reports Server (NTRS)

Miller, Frank W.; Mitchell, Randy C.

1991-01-01

An operational approach is proposed to managing the Data Management System Local Area Network (LAN) on Space Station Freedom. An overview of the onboard LAN elements is presented first, followed by a proposal of the operational guidelines by which management of the onboard network may be effected. To implement the guidelines, a recommendation is then presented on a set of network management parameters which should be made available in the onboard Network Operating System Computer Software Configuration Item and Fiber Distributed Data Interface firmware. Finally, some implications for the implementation of the various network management elements are discussed.

Materials for Adaptive Structural Acoustic Controls

DTIC Science & Technology

1994-01-31

non -184T walls are possibly active under a weak cternial driving field. I. INTRODUCTION sic and extrinsic contributions from tile experimental data...increased activity in non - I 8Or wall in PZT-500, The experimental methods presented in this however, the disproportionate increase in e. may refiect be...Electromechanical Nonlinearity of Ferroelecuic Ceramic and Related non 180" Domain Wall Motion. Feaoelectrics 139,25- 49 (1993). 14. Jiang, Q., W. Cao, and L E

Current Chinese Leadership: Background, Associations, and Issues for Selected Key Military Leaders

DTIC Science & Technology

1985-09-01

58 years old). Key leaders classified as conservative, such as Ye Jianying and Xu Xiangqian, lost their influential positions in September 1985...Cmte, CCP-CC (since Oct 83); VC, Central Greening Cmte (since Feb 82) Name;Jiang Xianchen Position; Deputy Chief, PLA GSD (since Mar 85) Name; Li ...Guang Position; Dir, Weapons & Equipment Dept, PLA GSD (since Nov 82) Name; Li Jing Position; Dep Cdr, PLA Navy (since Jul 83) Name; Li Jiulong

Quantum Phases of Matter in Optical Lattices

DTIC Science & Technology

2015-06-30

doi: 10.1103/PhysRevA.89.013625 Hyungwon Kim, David A. Huse. Ballistic Spreading of Entanglement in a Diffusive Nonintegrable System, Physical...Review B, (07 2013): 0. doi: 10.1103/PhysRevB.88.014206 Lin Dong, Lei Jiang, Han Pu. Fulde–Ferrell pairing instability in spin–orbit coupled Fermi...PhysRevA.87.051603 Kuei Sun, C. J. Bolech. Pair tunneling, phase separation, and dimensional crossover in imbalanced fermionic superfluids in a coupled

Co-occurring Mental Health and Alcohol Misuse Symptoms: Dual Disorder Symptoms in Combat Injured Veterans

DTIC Science & Technology

2014-03-03

required from Department of Veterans Af fairs hospitals. The rate of alcohol misuse among veterans screening for PTSD or de pression in the present...facilities only (casualties treated at forward deployed Army facilities, and those transported directly to Combat Support Hospitals from the point of injury...Psychiatry, 163, 1777–1783. Hien, D. A., Jiang, H., Campbell, A. N. C., Hu, M. C., Miele , G. M., Cohen, L. R., et al. (2010). Do treatment improvements

Network Characteristics and Dynamics: Reciprocity, Competition and Information Dissemination

DTIC Science & Technology

2015-09-01

AND INFORMATION DISSEMINATION A Dissertation Presented by BO JIANG Approved as to style and content by: Don Towsley, Chair Weibo Gong, Member Matthias...my parents . ACKNOWLEDGMENTS I would like to express my deepest thanks to my advisor, Prof. Don Towsley, who has always been encouraging, supportive...deepest gratitude to my parents and all my extended family members for their constant love and support. This work was supported in part by DoD ARO MURI

TWSTFT Data Treatment for UTC Time Transfer

DTIC Science & Technology

2009-11-01

41 st Annual Precise Time and Time Interval (PTTI) Meeting 409 TWSTFT DATA TREATMENT FOR UTC TIME TRANSFER Z. Jiang, W...Abstract TWSTFT (TW) is the primary technique of time and frequency transfers used at BIPM for the UTC/TAI generations. At present, some 19...number. 1. REPORT DATE NOV 2009 2. REPORT TYPE 3. DATES COVERED 00-00-2009 to 00-00-2009 4. TITLE AND SUBTITLE TWSTFT Data Treatment for UTC Time

Calibrating GPS With TWSTFT For Accurate Time Transfer

DTIC Science & Technology

2008-12-01

40th Annual Precise Time and Time Interval (PTTI) Meeting 577 CALIBRATING GPS WITH TWSTFT FOR ACCURATE TIME TRANSFER Z. Jiang1 and...primary time transfer techniques are GPS and TWSTFT (Two-Way Satellite Time and Frequency Transfer, TW for short). 83% of UTC time links are...Calibrating GPS With TWSTFT For Accurate Time Transfer 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT

Time and Frequency Activities at the U.S. Naval Observatory

DTIC Science & Technology

2009-11-01

Massachusetts, USA (Institute of Navigation, Alexandria, Virginia). [22] D. Kirchner, 1999, “Two Way Satellite Time and Frequency Transfer ( TWSTFT ...Piester, D., and Z. Jiang, 2009, “Two-Way Satellite Time and Frequency ( TWSTFT ) Transfer Calibration Constancy from Closure Sums,” in Proceedings of...Shäfer, and A. Pawlitzki, 2005, “Development of Carrier- Phase-Based Two-Way Satellite Time and Frequency Transfer ( TWSTFT ),” in Proceedings of the 36 th

Efficient Symbolic Task Planning for Multiple Mobile Robots

DTIC Science & Technology

2016-12-13

Efficient Symbolic Task Planning for Multiple Mobile Robots Yuqian Jiang December 13, 2016 Abstract Symbolic task planning enables a robot to make...high-level deci- sions toward a complex goal by computing a sequence of actions with minimum expected costs. This thesis builds on a single- robot ...time complexity of optimal planning for multiple mobile robots . In this thesis we first investigate the performance of the state-of-the-art solvers of

Study the Effect of KSL-W on Inflammatory Response of Engineered Human Oral Mucosa Following Candida albicans Infection

DTIC Science & Technology

2010-08-01

the control roup and the KSL-W-treated group. Heat-inactivated KSL-W did ot affect epithelial cell proliferation (Fig. 2). .3. KSL-W pre-treatment...However, their potential effect against fungi , such as C. albi- cans, remains to be determined. Oral candidiasis is associatedwith gingival...Ingroff A. Mechanisms of resistance to antifungal agents: yeasts and filamentous fungi . Rev Iberoam Micol 2008;25:101–6. 14] Feng Z, Jiang B, Chandra J

Given the Absence of Established Doctrine, are there Concepts and Doctrinal Guidance Available from Varying Sources, Which are Relevant to Shaping the Capabilities of the Jamaica Defence Force to Achieve its Mission in the 21st Century

DTIC Science & Technology

2010-12-10

the ruling People’s National Party (PNP) and Fidel Castro, communist leader of Cuba . The opposition party at the time was the Jamaica Labour Party...Sea. It is approximately, 145 kilometers (90 miles) south of Cuba . Its coastline extends for 1,022 kilometers (634 miles). Jamaica practices a...Qin, Chairman Mao Tse-tung, Deng Xiaoping and Jiang Zemin. The foundation principles of Marxism are revered and built upon by the respective military

Complex Seismic Anisotropy at the Edges of a Very-low Velocity Province in the Lowermost Mantle

NASA Astrophysics Data System (ADS)

Wang, Y.; Wen, L.

2005-12-01

A prominent very-low velocity province (VLVP) in the lowermost mantle is revealed, and has been extensively mapped out in recent seismic studies (e.g., Wang and Wen, 2004). Seismic evidence unambiguously indicates that the VLVP is compositionally distinct, and its seismic structure can be best explained by partial melting driven by a compositional change produced in the early Earth's history (Wen, 2001; Wen et. al, 2001; Wang and Wen, 2004). In this presentation, we study the seismic anisotropic behavior inside the VLVP and its surrounding area using SKS and SKKS waveform data. We collect 272 deep earthquakes recorded by more than 80 stations in the Kaapvaal seismic array in southern Africa from 1997 to 1999. Based on the data quality, we choose SKS and SKKS waveform data for 16 earthquakes to measure the anisotropic parameters: the fast polarization direction and the splitting time, using the method of Silver and Chan (1991). A total of 162 high-quality measurements are obtained based on the statistics analysis of shear wave splitting results. The obtained anisotropy exhibits different patterns for the SKS and SKKS phases sampling inside the VLVP and at the edges of the VLVP. When the SKS and SKKS phases sample inside the VLVP, their fast polarization directions exhibit a pattern that strongly correlates with stations, gradually changing from 11°N~to 80°N~across the seismic array from south to north and rotating back to the North direction over short distances for several northernmost stations. The anisotropy pattern obtained from the analysis of the SKKS phases is the same as that from the SKS phases. However, when the SKS and SKKS phases sample at the edges of the VLVP, the measured anisotropy exhibits a very complex pattern. The obtained fast polarization directions change rapidly over a small distance, and they no longer correlate with stations; the measurements obtained from the SKS analysis also differ with those from the SKKS analysis. As the SKS and SKKS

Audit Report, "Fire Protection Deficiencies at Los Alamos National Laboratory"

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

2009-06-01

The Department of Energy's Los Alamos National Laboratory (Los Alamos) maintains some of the Nation's most important national security assets, including nuclear materials. Many of Los Alamos' facilities are located in close proximity to one another, are occupied by large numbers of contract and Federal employees, and support activities ranging from nuclear weapons design to science-related activities. Safeguarding against fires, regardless of origin, is essential to protecting employees, surrounding communities, and national security assets. On June 1, 2006, Los Alamos National Security, LLC (LANS), became the managing and operating contractor for Los Alamos, under contract with the Department's National Nuclearmore » Security Administration (NNSA). In preparation for assuming its management responsibilities at Los Alamos, LANS conducted walk-downs of the Laboratory's facilities to identify pre-existing deficiencies that could give rise to liability, obligation, loss or damage. The walk-downs, which identified 812 pre-existing fire protection deficiencies, were conducted by subject matter professionals, including fire protection experts. While the Los Alamos Site Office has overall responsibility for the effectiveness of the fire protection program, LANS, as the Laboratory's operating contractor, has a major, day-to-day role in minimizing fire-related risks. The issue of fire protection at Los Alamos is more than theoretical. In May 2000, the 'Cerro Grande' fire burned about 43,000 acres, including 7,700 acres of Laboratory property. Due to the risk posed by fire to the Laboratory's facilities, workforce, and surrounding communities, we initiated this audit to determine whether pre-existing fire protection deficiencies had been addressed. Our review disclosed that LANS had not resolved many of the fire protection deficiencies that had been identified in early 2006: (1) Of the 296 pre-existing deficiencies we selected for audit, 174 (59 percent) had not been

Benchmarking Insulin Treatment Persistence Among Patients with Type 2 Diabetes Across Different U.S. Payer Segments.

PubMed

Wei, Wenhui; Jiang, Jenny; Lou, Youbei; Ganguli, Sohini; Matusik, Mark S

2017-03-01

treatment persistence across different payers in the United States. Findings indicate that basal insulin persistence patterns are significantly different across different payers, basal insulin types, and devices. This information may be useful in developing targeted approaches to improve T2D patients' persistence with insulin treatment for better glycemic control. This study was funded by Sanofi U.S. through a grant provided to Walgreens for research services. Matusik, Jiang, and Lou are employed by Walgreen Co. Wei and Ganguli were employed by Sanofi U.S. at the time of this study. Study concept and design were contributed by Wei, Ganguli, and Matusik, with assistance from Lou. Jiang took the lead in data collection, along with Lou, and data interpretation was performed by Wei, Lou, and Jiang, along with Ganguli and Matusik. The manuscript was written by Wei and Jiang, along with Ganguli and Matusik, and revised by Wei and Ganguli, along with the other authors.

Uncovering the Physical Basis Connecting Environment and Tribological Performance of Ultrananocrystalline Diamond

DTIC Science & Technology

2012-10-05

Anisotropic Nanotribological Properties,” Journal of the Mechanical Behavior of Biomedical Materials, Vol. 4, Issue 4, pp. 515-522 (SCI) Kuo -Cheng Chen...Nanodiamond With the Polymer Used as an Additive in Lubricant Oil,” Journal of Materials Chemistry, Vol. 21, pp. 13213-13222 (SCI) Chih- Jung Chen, Ray...Deep Submicron to Nano-Scale,” Journal of Mechanics, Vol. 28, Issue 3, pp. 507-511 (SCI) Yeau-Ren Jeng, Yi-Min Wang, Hua-Chiang Wen, Shih -Ming Huang

High Throughput Optical Lithography by Scanning a Massive Array of Bowtie Aperture Antennas at Near-Field

DTIC Science & Technology

2015-11-03

scale optical projection system powered by spatial light modulators, such as digital micro-mirror device ( DMD ). Figure 4 shows the parallel lithography ...1Scientific RepoRts | 5:16192 | DOi: 10.1038/srep16192 www.nature.com/scientificreports High throughput optical lithography by scanning a massive...array of bowtie aperture antennas at near-field X. Wen1,2,3,*, A. Datta1,*, L. M. Traverso1, L. Pan1, X. Xu1 & E. E. Moon4 Optical lithography , the

Cooperativity Between Oncogenic PKC Epsilon and Pten Loss in Prostate Cancer Progression

DTIC Science & Technology

2015-10-01

AWARD NUMBER: W81XWH-14-1-0535 TITLE: “Cooperativity Between Oncogenic PKC Epsilon and Pten Loss in Prostate Cancer Progression” PRINCIPAL...3. DATES COVERED 30 Sep 2014 - 29 Sep 2015 4. TITLE AND SUBTITLE 5a. CONTRACT NUMBER Cooperativity Between Oncogenic PKC Epsilon and Pten Loss in...the s-econd leadi.ng caus.e of cmcer-related deaths .unong wen in thee United States. Protein kinase C epsilon (PKCs), a me-mber of the PKC £uuily

People’s Republic of China Scientific Abstracts, Number 177

DTIC Science & Technology

1977-10-06

PAO [ARCHITECTURAL JOURNAL] No 2, June 1977 1 CHIH-WU HSUEH-PAO [ACTA BOTANICA SINICA] No 4, December 1976 13 CHIH-WU TSA-CHIH [JOURNAL OF BOTANY...10424 CSO: 4009 12 ACTA BOTANICA SINICA AUTHOR: None ORG: Three-in-one Combination Experimental Group of Peking Ch’ung-wen Vegetable Station...Physiological Processes of Stored Tomatoes" SOURCE: Peking CHIH-WU HSUEH-PAO [ACTA BOTANICA SINICA] in Chinese Vol 18, No 4, Dec 76 pp 278-283 TEXT OF

Preclinical Studies of Induced Pluripotent Stem Cell-Derived Astrocyte Transplantation in ALS

DTIC Science & Technology

2014-12-01

fast-frozen in liquid nitrogen. RNAwas iso- lated using TRIzol, followed by DNase treatment and RNA cleanup using RNeasy columns (Qiagen, Hilden, Germany...J Neurochem 2001;79:737–746. 34 Doi A, Park IH, Wen B et al. Differential methylation of tissue- and cancer-specific CpG island shores distinguishes...2008, Sreedharan et al., 2008, Kwiatkowski et al., 2009, Vance et al., 2009, Johnson et al., 2010, Maruyama et al., 2010, DeJesus-Hernandez et al

Outdoor Light at Night and Breast Cancer Incidence in the Nurses’ Health Study II

PubMed Central

Bertrand, Kimberly A.; Hart, Jaime E.; Schernhammer, Eva S.; Tamimi, Rulla M.; Laden, Francine

2017-01-01

Background: Animal and epidemiologic studies suggest that exposure to light at night (LAN) may disrupt circadian patterns and decrease nocturnal secretion of melatonin, which may disturb estrogen regulation, leading to increased breast cancer risk. Objectives: We examined the association between residential outdoor LAN and breast cancer incidence using data from the nationwide U.S.-based Nurses’ Health Study II cohort. Methods: We followed 109,672 women from 1989 through 2013. Cumulative LAN exposure was estimated using time-varying satellite data for a composite of persistent nighttime illumination at ∼1 km2 scale for each residence during follow-up. Incident invasive breast cancer cases were confirmed by medical record review. We used Cox proportional hazard models to calculate hazard ratios (HRs) and 95% confidence intervals (CIs), adjusting for anthropometric, reproductive, lifestyle, and socioeconomic risk factors. Results: Over 2,187,425 person-years, we identified 3,549 incident breast cancer cases. Based on a fully adjusted model, the estimated HR for incident breast cancer with an interquartile range (IQR) (31.6 nW/cm2/sr) increase in cumulative average outdoor LAN was 1.05 (95% CI: 1.00, 1.11). An association between LAN and breast cancer appeared to be limited to women who were premenopausal at the time of a case [HR=1.07 (95% CI: 1.01, 1.14) based on 1,973 cases vs. HR=1.00 (95% CI: 0.91, 1.09) based on 1,172 cases in postmenopausal women; p-interaction=0.08]. The LAN–breast cancer association was observed only in past and current smokers at the end of follow-up [HR=1.00 (95% CI: 0.94, 1.07) based on 2,215 cases in never smokers; HR=1.10 (95% CI: 1.01, 1.19) based on 1,034 cases in past smokers vs. HR=1.21 (95% CI: 1.07, 1.37) for 300 cases in current smokers; p-interaction=0.08]. Conclusions: Although further work is required to confirm our results and to clarify potential mechanisms, our findings suggest that exposure to residential outdoor

An ultra low noise telecom wavelength free running single photon detector using negative feedback avalanche diode

NASA Astrophysics Data System (ADS)

Yan, Zhizhong; Hamel, Deny R.; Heinrichs, Aimee K.; Jiang, Xudong; Itzler, Mark A.; Jennewein, Thomas

2012-07-01

It is challenging to implement genuine free running single-photon detectors for the 1550 nm wavelength range with simultaneously high detection efficiency (DE), low dark noise, and good time resolution. We report a novel read out system for the signals from a negative feedback avalanche diode (NFAD) [M. A. Itzler, X. Jiang, B. Nyman, and K. Slomkowski, "Quantum sensing and nanophotonic devices VI," Proc. SPIE 7222, 72221K (2009), 10.1117/12.814669; X. Jiang, M. A. Itzler, K. ODonnell, M. Entwistle, and K. Slomkowski, "Advanced photon counting techniques V," Proc. SPIE 8033, 80330K (2011), 10.1117/12.883543; M. A. Itzler, X. Jiang, B. M. Onat, and K. Slomkowski, "Quantum sensing and nanophotonic devices VII," Proc. SPIE 7608, 760829 (2010), 10.1117/12.843588], which allows useful operation of these devices at a temperature of 193 K and results in very low darkcounts (˜100 counts per second (CPS)), good time jitter (˜30 ps), and good DE (˜10%). We characterized two NFADs with a time-correlation method using photons generated from weak coherent pulses and photon pairs produced by spontaneous parametric down conversion. The inferred detector efficiencies for both types of photon sources agree with each other. The best noise equivalent power of the device is estimated to be 8.1 × 10-18 W Hz-1/2, more than 10 times better than typical InP/InGaAs single photon avalanche diodes (SPADs) show in free running mode. The afterpulsing probability was found to be less than 0.1% per ns at the optimized operating point. In addition, we studied the performance of an entanglement-based quantum key distribution (QKD) using these detectors and develop a model for the quantum bit error rate that incorporates the afterpulsing coefficients. We verified experimentally that using these NFADs it is feasible to implement QKD over 400 km of telecom fiber. Our NFAD photon detector system is very simple, and is well suited for single-photon applications where ultra-low noise and free

Sex and Trait Anxiety Differences in Psychological Stress are Modified by Environment.

PubMed

Liu, James; Scira, John; Donaldson, Simone; Kajiji, Nina; Dash, Gordon H; Donaldson, S Tiffany

2018-05-09

Evidence-based research has revealed how physiological and emotional responses to acute stress are adaptive. However, under conditions of unpredictable or protracted stress, health and drug vulnerability can be compromised. In this study, we examined anxiety-like behavioral responses of 4th generation adolescent male and female Long Evans rats selectively bred for high (HAn) and low (LAn) anxiety-like behavior when housed in an isolated environment (IE) versus a social environment (SE). After 35 days in IE or SE, animals were tested in the elevated plus maze (EPM), injected with amphetamine (AMPH: 0.5 mg/kg, IP) in the locomotor activity (LMA) chamber, measured for basal and post air puff-stressor core body temperature and blood pressure. Following select rearing, SE reduced the anxiogenic response in HAn rats with females displaying the lowest anxiety-like behavior in the EPM. During habituation in the LMA, IE rats remained active, while post-AMPH injection HAn females were hyperactive, followed closely by LAn females. Our findings from the post-stressor physiological measurements indicate that temperature differences due to environment are observed only in the SE females. We also observed group differences for diastolic (DBP) and systolic (SBP) blood pressure. HAn IE males experienced higher DBP and SBP but LAn IE females only experienced higher SBP. Not only do our findings corroborate earlier work on HAn/LAn lines but the findings obtained from this research offer new insights about the role of environment and the role of sex in (1) modulation of anxiety-like behavior, (2) AMPH sensitivity, and (3) basal and stress-induced physiological changes. Copyright © 2018 IBRO. Published by Elsevier Ltd. All rights reserved.

2013 Los Alamos National Laboratory Hazardous Waste Minimization Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Salzman, Sonja L.; English, Charles J.

2015-08-24

Waste minimization and pollution prevention are inherent goals within the operating procedures of Los Alamos National Security, LLC (LANS). The US Department of Energy (DOE) and LANS are required to submit an annual hazardous waste minimization report to the New Mexico Environment Department (NMED) in accordance with the Los Alamos National Laboratory (LANL or the Laboratory) Hazardous Waste Facility Permit. The report was prepared pursuant to the requirements of Section 2.9 of the LANL Hazardous Waste Facility Permit. This report describes the hazardous waste minimization program (a component of the overall Waste Minimization/Pollution Prevention [WMin/PP] Program) administered by the Environmentalmore » Stewardship Group (ENV-ES). This report also supports the waste minimization and pollution prevention goals of the Environmental Programs Directorate (EP) organizations that are responsible for implementing remediation activities and describes its programs to incorporate waste reduction practices into remediation activities and procedures. LANS was very successful in fiscal year (FY) 2013 (October 1-September 30) in WMin/PP efforts. Staff funded four projects specifically related to reduction of waste with hazardous constituents, and LANS won four national awards for pollution prevention efforts from the National Nuclear Security Administration (NNSA). In FY13, there was no hazardous, mixedtransuranic (MTRU), or mixed low-level (MLLW) remediation waste generated at the Laboratory. More hazardous waste, MTRU waste, and MLLW was generated in FY13 than in FY12, and the majority of the increase was related to MTRU processing or lab cleanouts. These accomplishments and analysis of the waste streams are discussed in much more detail within this report.« less

Wood processing wastes recovery and composted product field test

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chang, C.T.; Lin, K.L.

1997-12-31

Lumber mill waste, more than 3,000 tons per month, is one of the main waste sources in I-Lan area. Most of the lumber mill waste is sawdust which takes a large parts of organic-containing wastes in I-Lan county. Wastes from seafood plants around the Sueou Harbor causes a treatment problem because of their high nitrogen and phosphorous concentrations. Furthermore, the distiller-by products in I-Lan Winery are easy to become spoiled and result in odor. In this study, the compost method is suggested to deal with these waste problems and make energy recovery. Microorganisms incubating in the laboratory provide the stablemore » seed needed for composting. Flowers and vegetable raising are scheduled to be used in field to verify the efficiency of the products. The optimal combination ration of wastes and operation criteria then will be concluded in this study after economic analyzing. The results show that the Zinnia elegans leaves growth is relative with organic fertilizer. It can also be illustrated from the statistical value that the F value is 19.4 and above the critical value 9.4.« less

A Genetic Algorithm for the Bi-Level Topological Design of Local Area Networks

PubMed Central

Camacho-Vallejo, José-Fernando; Mar-Ortiz, Julio; López-Ramos, Francisco; Rodríguez, Ricardo Pedraza

2015-01-01

Local access networks (LAN) are commonly used as communication infrastructures which meet the demand of a set of users in the local environment. Usually these networks consist of several LAN segments connected by bridges. The topological LAN design bi-level problem consists on assigning users to clusters and the union of clusters by bridges in order to obtain a minimum response time network with minimum connection cost. Therefore, the decision of optimally assigning users to clusters will be made by the leader and the follower will make the decision of connecting all the clusters while forming a spanning tree. In this paper, we propose a genetic algorithm for solving the bi-level topological design of a Local Access Network. Our solution method considers the Stackelberg equilibrium to solve the bi-level problem. The Stackelberg-Genetic algorithm procedure deals with the fact that the follower’s problem cannot be optimally solved in a straightforward manner. The computational results obtained from two different sets of instances show that the performance of the developed algorithm is efficient and that it is more suitable for solving the bi-level problem than a previous Nash-Genetic approach. PMID:26102502

Vibrational spectra, DFT quantum chemical calculations and conformational analysis of P-iodoanisole.

PubMed

Arivazhagan, M; Anitha Rexalin, D; Geethapriya, J

2013-09-01

The solid phase FT-IR and FT-Raman spectra of P-iodoanisole (P-IA) have been recorded in the regions 400-4000 and 50-4000 cm(-1), respectively. The spectra were interpreted in terms of fundamentals modes, combination and overtone bands. The structure of the molecule was optimized and the structural characteristics were determined by ab initio (HF) and density functional theory (B3LYP) methods with LanL2DZ as basis set. The potential energy surface scan for the selected dihedral angle of P-IA has been performed to identify stable conformer. The optimized structure parameters and vibrational wavenumbers of stable conformer have been predicted by density functional B3LYP method with LanL2DZ (with effective core potential representations of electrons near the nuclei for post-third row atoms) basis set. The nucleophilic and electrophilic sites obtained from the molecular electrostatic potential (MEP) surface were calculated. The temperature dependence of thermodynamic properties has been analyzed. Several thermodynamic parameters have been calculated using B3LYP with LanL2DZ basis set. Copyright © 2013 Elsevier B.V. All rights reserved.

The Shock and Vibration Digest, Volume 17, Number 11

DTIC Science & Technology

1985-11-01

Jiang, C., and Chia , 1983). C.Y., "Dynamic and Static Nonlinear Analy- .sis of Cylindrically Orthotropic Circular 122. Nowinski, J.L., "On the...Rectilinearly Orthotropic Disk," Intl. J. (1984). Mech. Sci., j2 (3), pp 191-198 (1983). 132. Sathyamootthy, M. and Chia , C.Y., 123. Sathyamoorthy, M...34Geometrically Nonlinear Transient Analysis of Laminated Composite 139. Chia , C.Y., "Large Amplitude Vibra- Plates," AIAA J., 21 (4), pp 621-629 (Apr tions of

JPRS Report, China.

DTIC Science & Technology

1993-02-09

Birth Control Measures [RENKOU YU JINGJI25 Oct] 37 Conference on Population Problems in Southwest [RENKOU YU JINGJI 25 Oct] -. 38 Southern JiangsU... Birth Control Measures 93CE0171A Beijing RENKOU YU JINGJI [POPULATION AND ECONOMICS] in Chinese No 74, 25 Oct 92 pp 43-45 [Article by Deng Guosheng...6772 0948 0524), affiliated with the Population Department of Jiangxi Teachers College: "More Attention Needs To Be Paid to Our Poor Birth Control Results

Toward Development of a Field-Deployable Imaging Device for TBI

DTIC Science & Technology

2015-06-01

proportional to the Young modulus with the following relationship: E = 3ρc2, where E is the Young modulus (kilopascals), a measure of the resistance of...Fang M, Jiang WQ, Zhu GF, Zeng HK. Effect of hydroxyethyl starch on intracranial pressure and plasma colloid osmotic pressure in rats with cerebral...creates images of Young’s Modulus, a measure of 81 the resistance to such that larger values describe stiffer tissue. Therefore, maps of Young’s 82

Annual Staunton Hill Conference on China’s People Liberation Army (PLA) (2nd) Held in Staunton Hill, Virginia on September 6 - 8, 1991

DTIC Science & Technology

1991-09-01

discipline; 3) regionalism; 4) directly to consolidate the position of the Li Peng the succession to Deng; ind 5) reaction to the Soviet group. coup...by local fact that the 21st century policy serves the narrow leaders, local protectionism (most often in the form interest of Li Peng and not the...elite, Li Peng, Jiang Zemin, and debates over the PLA and its future political role are Yang Shangkun, only Yang has credibility with the calls for a

Transrectal Near-Infrared Optical Tomography for Prostate Imaging

DTIC Science & Technology

2009-03-01

using a directional transurethral ultrasound applicator,” J Magn Reson Imaging., 15(4), 409-17. Iftimia N , and Jiang H (2000), “Quantitative... N , Carroll PR, Flax J, Blumenfeld W, and Folkman J (1993), "Tumor angiogenesis correlates with metastasis in invasive prostate carcinoma," Am J...34 JAMA. 281, 1591-1597 (1999). 6. A. C. Loch, A. Bannowsky, L. Baeurle, B. Grabski, B. König, G. Flier, O. Schmitz-Krause, U. Paul , and T. Loch

No Evidence for an Item Limit in Change Detection (Open Access)

DTIC Science & Technology

2013-02-28

memory : a reconsideration of mental storage capacity. Behav Brain Sci 24: 87–114. 17. Eng HY, Chen D, Jiang Y (2005) Visual working memory for simple...working memory can hold no more than a fixed number of items (‘‘item-limit models’’). Recent findings force us to consider the alternative view that working... memory is limited by the precision in stimulus encoding, with mean precision decreasing with increasing set size (‘‘continuous-resource models

Solubility Report of 1-Methyl-3,5-Dinitro-1H-1,2,4-Triazole (MDNT) and 2-Methyl-4,5-Dinitro-2H-1,2,3-Triazole 1-Oxide (MDNTO) for Co-Crystallization Screen

DTIC Science & Technology

2015-11-01

New Co-Crystals,” Crystal Growth & Design, Vol. 9, No. 3, pp. 1531-1537, 2009. 2 Landenberger, K., Matzger, A., “ Cocrystal Engineering of a...Y., Li, H., Zhou, Y., Zhou, J., Geo, T., Zhang, H., Jiang, G., “Toward Low- Sensitive and High-Energetic Cocrystal 1: Evaluation of the Power and the...Safety of Observed Energetic Cocrystals ,” CrystEngComm, 15, 4003-4014, 2013. 4 Levinthal, M.L., “Propellant Made With Cocrystals of

Fiber Strength of Hi Nicalon(TM) S After Oxidation and Scale Crystallization in Si(OH)4 Saturated Steam (Postprint)

DTIC Science & Technology

2017-02-06

conducted for the longest times because the fibers would completely oxidize. The SiO2 tube would warp during experiments run at temperatures over 1200° C ...Chollon, G.; Labrugere, C .; Lahaye, M.; Guette, A.; Bruneel, J . L.; Couzi, M.; Naslain, R.; Jiang, D. L., Characterization of Nearly Stoichiometric...Electron Beam Irradiation Curing - A Review. J . Ceram. Soc. Japan 2006, 114, 455-460. 8. Sauder, C .; Lamon, J ., Tensile Creep Behavior of SiC-Based Fibers

Effects of Early Acute Care on Autonomic Outcomes in SCI: Bedside to Bench and Back

DTIC Science & Technology

2015-10-01

fractures in the US military. Spine J. 2012;12(9):777–83. [PMID:21393068] http://dx.doi.org/10.1016/j.spinee.2011.01.029 3. Macciocchi S, Seel RT...47. Dai, L.Y., Wang, X.Y. and Jiang, L.S. (2007). Neurologic recovery from thoracolumbar burst fractures : is it predicted by the amount of initial...patients (15%) also presented with a concurrent traumatic brain injury. Additional complications and comorbidi- ties included 1 pulmonary embolism without

Using Wave-Current Observation to Predict Bottom Sediment Processes on Muddy Beaches

DTIC Science & Technology

2011-09-30

as 80% of wave energy over a distance of just a few wave lengths (Gade, 1957; Jiang and Mehta, 1995; deWitt, 1995; Hill and Foda , 1999; Chan and Liu...bed transformation (see Section Figure 1) emerges from the analysis Sheremet et al., 2005; Jaramillo et al., 2008; Robillard, 2009; Sahin et al...Kaihatu et al., 2007; Sheremet et al., 2010). The ongoing work has three directions of research: Data analysis : reconstruct the sequence of bed

Self-Replenishing Vascularized Fouling-Release Surfaces

DTIC Science & Technology

2014-01-01

similar results. Surfaces submerged for 12 days in static cultures of B. braunii, a green microalga known for its potential in the algae biofuels...Technol. 2004, 32, 219−222. (12) Kirschner, C. M.; Brennan, A. B. Bio -Inspired Antifouling Strategies. Annu. Rev. Mater. Res. 2012, 42, 211−229. (13...Release from Fouling Release Coatings. Biofouling 2000, 15, 73−81. (25) Liu, K.; Jiang, L. Bio -Inspired Self-Cleaning Surfaces. Annu. Rev. Mater. Res

Modeling Concept Dependencies for Event Detection

DTIC Science & Technology

2014-04-04

Gaussian Mixture Model (GMM). Jiang et al . [8] provide a summary of experiments for TRECVID MED 2010 . They employ low-level features such as SIFT and...event detection literature. Ballan et al . [2] present a method to introduce temporal information for video event detection with a BoW (bag-of-words...approach. Zhou et al . [24] study video event detection by encoding a video with a set of bag of SIFT feature vectors and describe the distribution with a

Telescience workstation

NASA Technical Reports Server (NTRS)

Brown, Robert L.; Doyle, Dee; Haines, Richard F.; Slocum, Michael

1989-01-01

As part of the Telescience Testbed Pilot Program, the Universities Space Research Association/ Research Institute for Advanced Computer Science (USRA/RIACS) proposed to support remote communication by providing a network of human/machine interfaces, computer resources, and experimental equipment which allows: remote science, collaboration, technical exchange, and multimedia communication. The telescience workstation is intended to provide a local computing environment for telescience. The purpose of the program are as follows: (1) to provide a suitable environment to integrate existing and new software for a telescience workstation; (2) to provide a suitable environment to develop new software in support of telescience activities; (3) to provide an interoperable environment so that a wide variety of workstations may be used in the telescience program; (4) to provide a supportive infrastructure and a common software base; and (5) to advance, apply, and evaluate the telescience technolgy base. A prototype telescience computing environment designed to bring practicing scientists in domains other than their computer science into a modern style of doing their computing was created and deployed. This environment, the Telescience Windowing Environment, Phase 1 (TeleWEn-1), met some, but not all of the goals stated above. The TeleWEn-1 provided a window-based workstation environment and a set of tools for text editing, document preparation, electronic mail, multimedia mail, raster manipulation, and system management.

Adolescent calorie/fat menu ordering at fast food restaurants compared to other restaurants.

PubMed

Yamamoto, Julienne A; Yamamoto, Joelle B; Yamamoto, Brennan E; Yamamoto, Loren G

2006-08-01

Childhood and adolescent obesity is an increasing public health problem. Fast food consumption has been linked to obesity. The purpose of this study is to determine adolescent calorie and fat consumption patterns at different types of restaurants. Study subjects (104 adolescents) were asked to order a dinner meal from 10 restaurant menus with an estimate of how much they would actually consume. A paired T-test was used to compare the calories and fat values for each restaurant vs. McDonald's. Mean calories/fat (g) ordered at each restaurant were: California Pizza Kitchen (CPK).: 1284/70, Chili's (Ch). 1333/62, Denny's (Den): 1226/61, McDonald's (MD): 1016/45, Outback Steakhouse (OS): 1656/93, Panda Express (PE): 873/29, Red Lobster (RL): 1016/49, Stuart Anderson's (SA). 1058/52, Taco Bell (TB): 800/34, Wendy's (Wen): 879/32. Calorie/fat content of the ordered items were significantly higher at CPK, Ch, Den, and OS compared to McDonald's. RL and SA were not significantly different from MD. Calorie/fat content of the ordered items were significantly lower at PE, TB and Wen compared with McDonald's. More calories/fat were ordered at many sit down restaurants compared to McDonald's. The lowest calories/fat were ordered at other fast food restaurants (Taco Bell, Wendy's and Panda Express).

AN EXTENDED AND MORE SENSITIVE SEARCH FOR PERIODICITIES IN ROSSI X-RAY TIMING EXPLORER/ALL-SKY MONITOR X-RAY LIGHT CURVES

DOE Office of Scientific and Technical Information (OSTI.GOV)

Levine, Alan M.; Bradt, Hale V.; Chakrabarty, Deepto

2011-09-01

We present the results of a systematic search in {approx}14 years of Rossi X-ray Timing Explorer All-Sky Monitor (ASM) data for evidence of periodicities. Two variations of the commonly used Fourier analysis search method have been employed to significantly improve upon the sensitivity achieved by Wen et al. in 2006, who also searched for periodicities in ASM data. In addition, the present search is comprehensive in terms of sources studied and frequency range covered, and has yielded the detection of the signatures of the orbital periods of eight low-mass X-ray binary systems and of ten high-mass X-ray binaries not listedmore » in the tables of Wen et al. Orbital periods, epochs, signal amplitudes, modulation fractions, and folded light curves are given for each of these systems. Seven of the orbital periods are the most precise reported to date. In the course of this work, the 18.545 day orbital period of IGR J18483-0311 was co-discovered, and the first detections in X-rays were made of the {approx}3.9 day orbital period of LMC X-1 and the {approx}3.79 hr orbital period of 4U 1636-536. The results inform future searches for orbital and other periodicities in X-ray binaries.« less

Broadband enhanced transmission of acoustic waves through serrated metal gratings

NASA Astrophysics Data System (ADS)

Qi, Dong-Xiang; Fan, Ren-Hao; Deng, Yu-Qiang; Peng, Ru-Wen; Wang, Mu; Jiangnan University Collaboration

In this talk, we present our studies on broadband properties of acoustic waves through metal gratings. We have demonstrated that serrated metal gratings, which introduce gradient coatings, can give rise to broadband transmission enhancement of acoustic waves. Here, we have experimentally and theoretically studied the acoustic transmission properties of metal gratings with or without serrated boundaries. The average transmission is obviously enhanced for serrated metal gratings within a wide frequency range, while the Fabry-Perot resonance is significantly suppressed. An effective medium hypothesis with varying acoustic impedance is proposed to analyze the mechanism, which was verified through comparison with finite-element simulation. The serrated boundary supplies gradient mass distribution and gradient normal acoustic impedance, which could efficiently reduce the boundary reflection. Further, by increasing the region of the serrated boundary, we present a broadband high-transmission grating for wide range of incident angle. Our results may have potential applications to broadband acoustic imaging, acoustic sensing and new acoustic devices. References: [1] Dong-Xiang Qi, Yu-Qiang Deng, Di-Hu Xu, Ren-Hao Fan, Ru-Wen Peng, Ze-Guo Chen, Ming-Hui Lu, X. R. Huang and Mu Wang, Appl. Phys. Lett. 106, 011906 (2015); [2] Dong-Xiang Qi, Ren-Hao Fan, Ru-Wen Peng, Xian-Rong Huang, Ming-Hui Lu, Xu Ni, Qing Hu, and Mu Wang, Applied Physics Letters 101, 061912 (2012).

Tomographic and Geodynamic Constraints on Convection-Induced Mixing in Earth's Deep Mantle

NASA Astrophysics Data System (ADS)

Hafter, D. P.; Forte, A. M.; Bremner, P. M.; Glisovic, P.

2017-12-01

Seismological studies reveal two large low-shear-velocity provinces (LLSVPs) in the lowermost mantle (e.g., Su et al. 1994; Wang & Wen 2007; He & Wen 2012), which may represent accumulations of subducted slabs at the CMB (Tan & Gurnis 2005; Christensen & Hoffman 1994) or primordial material generated in the early differentiation of Earth (e.g. Li et al. 2014). The longevity or stability of these large-scale heterogeneities in the deep mantle depends on the vigor and spatial distribution of the convective circulation, which is in turn dependent on the distribution of mantle buoyancy and viscosity (e.g. Glisovic & Forte 2015). Here we explore the state of convective mixing in the mantle using the ASPECT convection code (Kronbichler et al. 2012). A series of experiments are conducted to consider the geochemical and dynamical contributions of LLSVPs to deep-mantle upwellings and corresponding plume-sourced volcanism. The principal feature of these experiments is the use of particle tracers to track geochemical changes in the LLSVPs and mantle plumes in addition to identifying those parts of the mantle that may remain unmixed. We employ 3-D mantle density anomalies derived from joint inversions of seismic, geodynamic and mineral physics constraints and geodynamically-constrained viscosity distributions (Glisovic et al. 2015) to ensure that the predicted flow fields yield a good match to key geophysical constraints (e.g. heat flow, global gravity anomalies and plate velocities).

COMMITTEES: SQM2006 Organising and International Advisory Committees

NASA Astrophysics Data System (ADS)

2006-12-01

Organising Committee Kenneth Barish Huan Zhong Huang Joseph Kapusta Grazyna Odyniec Johann Rafelski Charles A Whitten Jr International Advisory Committee Jörg Aichelin Federico Antinori Tamas Biró Jean Cleymans Lazlo Csernai Tim Hallman Ulrich Heinz Sonja Kabana Rob Lacey Yu-Gang Ma Jes Madsen Yasuo Miake Berndt Mueller Grazyna Odyniec Helmut Oeschler Apostolos Panagiotou Johann Rafelski Hans Ritter Karel Safarik Jack Sandweiss Jürgen Schaffner-Bielich Wen-Qing Shen Georges Stephans Horst Stöcker Thomas Ullrich Bill Zajc

A System for Fast Navigation of Autonomous Vehicles

DTIC Science & Technology

1991-09-01

AD-A243 523 4, jj A System for Fast Navigation of Autonomous Vehicles Sanjiv Singh, Dai Feng, Paul Keller, Gary Shaffer, Wen Fan Shi, Dong Hun Shin...FUNDING NUMBERS A System for Fast Navigation of Autonomous Vehicles 6. AUTHOR(S) S. Singh, D. Feng, P. Keller, G. Shaffer, W.F. Shi, D.H. Shin, J. West...common in the control of autonomous vehicles to establish the necessary kinematic models but to ignore an explicit representation of the vehicle dynamics

The Small Alternatively Spliced Amelogenin LRAP Modulates Early Stage Ameloblast Differentiation

DTIC Science & Technology

2014-01-30

Nguyen, V., Somogyi-Ganss, E., Snead, M.L., White, S.N., Paine , M.L., and Ganss, B. (2012). Targeted overexpression of amelotin disrupts the...microstructure of dental enamel. PloS one 7, e35200. Lacruz, R.S., Smith, C.E., Kurtz, I., Hubbard, M.J., and Paine , M.L. (2013). New paradigms on the...restorative dentistry 24, 326-333. Shapiro, J.L., Wen, X., Okamoto, C.T., Wang, H.J., Lyngstadaas, S.P., Goldberg, M., Snead, M.L., and Paine , M.L. (2007

Inhibition of Androgen-Independent Growth of Prostate Cancer by siRNA-Mediated Androgen Receptor Gene Silencing

DTIC Science & Technology

2006-02-01

was gradually increased along with increasing dosage of the AAV.ARHP8 particles injected. No GFP expression was observed in PBS-injected xenograft...receptor. Cancer Gene Ther 2002;9:117–25. 16. Craft N, Shostak Y , Carey M, Sawyers CL. A mechanism for hormone- independent prostate cancer through...modulation of androgen receptor signaling by the HER-2/neu tyrosine kinase. Nat Med 1999;5:280–5. 17. Wen Y , Hu MC, Makino K, et al. HER-2/neu promotes

Preliminary Investigations on the Fate of Terrestrial Sediments in the Coastal Ocean Discharged From Taiwanese Small Mountainous Rivers

DTIC Science & Technology

2009-01-01

Central University 300 Jung-da Rd., Jhongli, Taiwan 32001 phone: +886-3-422-3354, fax: +886-3-422-2894, email: kkliu@ncu.edu.tw Wen-Son Chiang...Tainan Hydraulics Laboratory, National Cheng-Kung University 500 An-Ming Road Sec. 3, Tainan, Taiwan 701 phone: +886-6-237-1938 ext 232, fax: +886-6...Taoyuan, Taiwan 32001 phone: +886-3-422-7151 ext 65690, fax: +886-3-422-2894, email: hchien@ncu.edu.tw Shu-Kun Hsu Department of Earth Science

Development of Nanostructure Materials and Architecture for High Performance Li-rechargeable Batteries with Ultrafast Charge Rate

DTIC Science & Technology

2011-04-22

overcome these difficulties extensive work has been done. Surface coatings with ZnO , SiO2, and Bi2O3 have been proposed to enhance stability of electrodes...Liu, G. Q.; Wen, L.; Liu, Y. M. Journal of Solid State Electrochemistry 2010, 14, 2191. (23) Myung, S. T.; Komaba, S.; Kumagai, N.; Yashiro, H.; Chung...Y. R.; Shu, J.; Zhu, R. S. Journal of Solid State Electrochemistry 2009, 13, 913. (29) Aklalouch, M.; Amarilla, J. M.; Rojas, R. M.; Saadoune, I