Pro-lipogenic Action of Lysophosphatidic Acid in Ovarian Cancer

DTIC Science & Technology

2014-04-01

Function. IUBMB Life. 2008. 60: 347-354. 11. Tse C, Shoemaker AR, Adickes J, Anderson MG, Chen J, Jin S, Johnson EF, Marsh KC , Mitten MJ, Nimmer P...Ann. Oncol. 9, 437–442 14. Choi, J. W., Herr, D. R., Noguchi, K., Yung, Y. C., Lee, C. W., Mutoh, T., Lin, M. E., Teo , S. T., Park, K. E., Mosley, A

Effects of low light on photosynthetic properties, antioxidant enzyme activity, and anthocyanin accumulation in purple pak-choi (Brassica campestris ssp. Chinensis Makino).

PubMed

Zhu, Hongfang; Li, Xiaofeng; Zhai, Wen; Liu, Yang; Gao, Qianqian; Liu, Jinping; Ren, Li; Chen, Huoying; Zhu, Yuying

2017-01-01

Anthocyanins are secondary metabolites that contribute to red, blue, and purple colors in plants and are affected by light, but the effects of low light on the physiological responses of purple pak-choi plant leaves are still unclear. In this study, purple pak-choi seedlings were exposed to low light by shading with white gauze and black shading in a phytotron. The responses in terms of photosynthetic properties, carbohydrate metabolism, antioxidant enzyme activity, anthocyanin biosynthetic enzyme activity, and the relative chlorophyll and anthocyanin content of leaves were measured. The results showed that chlorophyll b, intracellular CO2 content, stomatal conductance and antioxidant activities of guaiacol peroxidase, catalase and superoxide dismutase transiently increased in the shade treatments at 5 d. The malondialdehyde content also increased under low light stress, which damages plant cells. With the extension of shading time (at 15 d), the relative chlorophyll a, anthocyanin and soluble protein contents, net photosynthetic rate, transpiration rate, stomata conductance, antioxidant enzyme activities, and activities of four anthocyanin biosynthetic enzymes decreased significantly. Thus, at the early stage of low light treatment, the chlorophyll b content increased to improve photosynthesis. When the low light treatment was extended, antioxidant enzyme activity and the activity of anthocyanin biosynthesis enzymes were inhibited, causing the purple pak-choi seedlings to fade from purple to green. This study provides valuable information for further deciphering genetic mechanisms and improving agronomic traits in purple pak-choi under optimal light requirements.

ELINT Signal Processing Using Choi-Williams Distribution on Reconfigurable Computers for Detection and Classification of LPI Emitters

DTIC Science & Technology

2008-03-01

WVD Wigner - Ville Distribution xiv THIS PAGE INTENTIONALLY LEFT BLANK xv ACKNOWLEDGMENTS Many thanks to David Caliga of SRC Computer for his...11 2. Wigner - Ville Distribution .................................................................11 3. Choi-Williams... Ville Distribution ...................................12 Table 3. C Code Output for Wigner - Ville Distribution

Farmers of Jin county want fewer children.

PubMed

Xiao, M

1986-04-01

The economic reform practiced in the vast rural areas in China gives a great impetus to the vigorous development of rural economy and the the rapid improvement of living standard. Meanwhile, reform pounds at the traditional childbearing ideas. The striking change in the childbearing attitudes of the farmers of the Jin County is a good example. As the farmers of the country are getting well-off when the commodity economy develops rapidly with the rural economic reforms, their childbearing attitudes change. Profound changes have taken place in their mode of production and their life style. The young couples of the county begin to seek small families instead of traditional big ones. They are convinced that under the new situation of reforms, the farmers of an old generation are in no way competent as the head of the family to guide production and therefore want to build their own small families by freeing themselves from the binds of the traditional patriarchal system. The increase in the cost of bringing up children and the economic loss resulting from the absence from work for looking after children constitute another reason to prefer a small family. The son is no more the only economic guarantee for the aged. As a result of the rapid development of the rural economy, a retirement system has been established among the farmers of the Jin county. "It is unreliable to expect that the son will support his aged parents. Now it is better to earn more money and the collective can be depended upon by the aged."

Small data global solutions for the Camassa–Choi equations

NASA Astrophysics Data System (ADS)

Harrop-Griffiths, Benjamin; Marzuola, Jeremy L.

2018-05-01

We consider solutions to the Cauchy problem for an internal-wave model derived by Camassa–Choi (1996 J. Fluid Mech. 313 83–103). This model is a natural generalization of the Benjamin–Ono and intermediate long wave equations for weak transverse effects as in the case of the Kadomtsev–Petviashvili equations for the Korteweg-de Vries equation. For that reason they are often referred to as the KP-ILW or the KP–Benjamin–Ono equations regarding finite or infinite depth respectively. We prove the existence and long-time dynamics of global solutions from small, smooth, spatially localized initial data on . The techniques applied here involve testing by wave packet techniques developed by Ifrim and Tataru in (2015 Nonlinearity 28 2661–75 2016 Bull. Soc. Math. France 144 369–94).

US-Korea Nanotechnology, Biotechnology, and Information Technology (NBIT) Symbiosys Program - Phase 1

DTIC Science & Technology

2010-10-01

diameter, length, and spacing. Fabrication Technology: Synthesis of self-organized AAO ( Anodic aluminum oxide ) templates with controlled diameter...nanowires arrayed in anodized aluminum oxide ( AAO ) templates and the diameter is precisely controlled by using atomic layer deposition (ALD) process...Jin, “Highly Self-assembled Nanotubular Aluminum Oxide by Hard Anodization ”, J. Mater. Res. (in press, December 2010). 3. J.Y. Kim, K. Noh, C. Choi

2016 Summer Series - Jin-Woo Han: Vacuum Electronics in a Nanometer Era

NASA Image and Video Library

2016-06-07

Modern space vehicles rely on transistors. Radiation tolerance of space electronics is critical for space exploration beyond low Earth orbit. NASA Ames Research Center is investigating ways to overcome this issue using vacuums. Dr. Jin-Woo Han's lecture will present advancements in the use of vacuums to improve radiation immunity in space circuitry.

[National physician master Jin Shiyuan's dispensing technology of Aconiti Lateralis Radix Praeparata based on Li Shizhen's pharmaceutical academic thought].

PubMed

Yuan, Yi-Ping; Zhai, Hua-Qiang; Guo, Zhao-Juan; Zhang, Tian; Kong, Li-Ting; Jia, Xiao-Yu; Tian, Wei-Lan; Li, Rui

2016-05-01

To collect Li Shizhen's experience in Aconiti Lateralis Radix Praeparata identification and clinical application, compare and analyze national physician master Jin Shiyuan's practical operation and theoretical knowledge, which is beneficial for the inheritance and improvement of Aconiti Lateralis Radix Praeparata clinical dispensing technology. In the analysis process, CNKI, Wanfang and other databases were searched with "Aconiti Lateralis Radix Praeparata", "Li Shizhen", "pharmacological method state theory" "Jin Shiyuan" and "Chinese medicine dispensing technology" as the key words. In addition, Treatise on Febrile Disease, Compendium of Materia Medica, Chinese Pharmacopoeia(2015 edition), Notes to Medical Professions(Yi Zong Shuo Yue), and other medicine books were accessed to summarize the processing methods and decoction dosage of Aconiti Lateralis Radix Praeparata in both ancient and modern medicine, and in consideration of technical research and practice operation, Li Shizhen's description of Aconiti Lateralis Radix Praeparata and Professor Jin Shiyuan's research on Aconiti Lateralis Radix Praeparata dispensing technology were analyzed and collected. Li Shizhen recorded the nature identification and clinical application of Aconiti Lateralis Radix Praeparata by using pharmacological method state theory in Compendium of Materia Medica. National physician master Jin Shiyuan carries forward the essence of Li Shizhen's pharmaceutical academic thought with his own proficient knowledge structure in medicine, providing scientific pharmaceutical service for clinical application of Aconiti Lateralis Radix Praeparata Professor. Jin Shiyuan put forward the dispensing technology for the first time, including nature identification technology, clinical processing technology, clinical decocting technology, prescription coping technology, and class specifications of Aconiti Lateralis Radix Praeparata. In this paper, Aconiti Lateralis Radix Praeparata was used as an example

The second-phase development of the China JinPing underground laboratory

DOE PAGES

Li, Jianmin; Ji, Xiangdong; Haxton, Wick; ...

2015-03-24

During 2013-2015 an expansion of the China JinPing underground Laboratory (CJPL) will be undertaken along a main branch of a bypass tunnel in the JinPing tunnel complex. This second phase of CJPL will increase laboratory space to approximately 96,000 m³, which can be compared to the existing CJPL-I volume of ~ 4,000 m³. One design configuration has eight additional hall spaces, each over 60 m long and approximately 12 m in width, with overburdens of about 2.4 km of rock, oriented parallel to and away from the main water transport and auto traffic tunnels. There are additional possibilities for furthermore » expansions at a nearby second bypass tunnel and along the entrance and exit branches of both bypass tunnels, potentially leading to an expanded CJPL comparable in size to Gran Sasso. Concurrent with the excavation activities, planning is underway for dark matter and other rare-event detectors, as well as for geophysics/engineering and other coupled multi-disciplinary sensors. In the town meeting on 8 September, 2013 at Asilomar, CA, associated with the 13 th International Conference on Topics in Astroparticle and Underground Physics (TAUP), presentations and panel discussions addressed plans for one-ton expansions of the current CJPL germanium detector array of the China Darkmatter EXperiment (CDEX) collaboration and of the duel-phase xenon detector of the Panda-X collaboration, as well as possible new detector initiatives for dark matter studies, low-energy solar neutrino detection, neutrinoless double beta searches, and geoneutrinos. JinPing was also discussed as a site for a low-energy nuclear astrophysics accelerator. Geophysics/engineering opportunities include acoustic and micro-seismic monitoring of rock bursts during and after excavation, coupled-process in situ measurements, local, regional, and global monitoring of seismically induced radon emission, and electromagnetic signals. Additional ideas and projects will likely be developed in the next few

Study on embodied CO2 transfer between the Jing-Jin-Ji region and other regions in China: a quantification using an interregional input-output model.

PubMed

Chen, Mengmeng; Wu, Sanmang; Lei, Yalin; Li, Shantong

2018-05-01

Jing-Jin-Ji region (i.e., Beijing, Tianjin, and Hebei) is China's key development region, but it is also the leading and most serious air pollution region in China. High fossil fuel consumption is the major source of both carbon dioxide (CO 2 ) emissions and air pollutants. Therefore, it is important to reveal the source of CO 2 emissions to control the air pollution in the Jing-Jin-Ji region. In this study, an interregional input-output model was applied to quantitatively estimate the embodied CO 2 transfer between Jing-Jin-Ji region and other region in China using China's interregional input-output data in 2010. The results indicated that there was a significant difference in the production-based CO 2 emissions in China, and furthermore, the Jing-Jin-Ji region and its surrounding regions were the main regions of the production-based CO 2 emissions in China. Hebei Province exported a large amount of embodied CO 2 to meet the investment, consumption, and export demands of Beijing and Tianjin. The Jing-Jin-Ji regions exported a great deal of embodied CO 2 to the coastal provinces of southeast China and imported it from neighboring provinces.

Interprovincial transfer of embodied energy between the Jing-Jin-Ji area and other provinces in China: A quantification using interprovincial input-output model.

PubMed

Chen, Weiming; Wu, Sanmang; Lei, Yalin; Li, Shantong

2017-04-15

Commodity trade between regions implies a large amount of energy transfer. As an important economic growth pole of China, the Jing-Jin-Ji area (Beijing-Tianjin-Hebei) is also one of the areas with the largest energy consumption in China. Moreover, the primary energy consumer goods in this area are fossil fuels, such as coal. This has led to serious air pollution in the area. Therefore, the reduction of energy consumption under the premise of maintaining sustained economic growth is an important task of the Jing-Jin-Ji area. In this study, an interprovincial input-output model was applied to quantitatively estimate the embodied energy transfer between Jing-Jin-Ji area and other provinces in China. The results indicated that the Metal and nonmetal mineral processing industry and the Electrical, gas and water industry in the Jing-Jin-Ji area exported a large amount of embodied energy to the Yangtze River Delta and the Pearl River Delta. However, the embodied energy export of the Jing-Jin-Ji area mainly exported by Hebei province. Beijing and Tianjin even have some net import of embodied energy. The embodied energy transfer between Tianjin, Hebei and other provinces was mainly driven by investment, while the main media of embodied energy transfer between Beijing and other provinces was consumption. Therefore, we suggest that the Jing-Jin-Ji area should further increase the degree of dependence on other provinces' energy-intensive products and reduce the export of energy-intensive products. In addition, there should be difference in the energy and industrial policies among Beijing, Tianjin and Hebei, and the problems of high energy consumption and high proportion of heavy industry in Hebei should be first resolved. Copyright © 2017 Elsevier B.V. All rights reserved.

Opening end-of-life discussions: how to introduce Voicing My CHOiCES™, an advance care planning guide for adolescents and young adults.

PubMed

Zadeh, Sima; Pao, Maryland; Wiener, Lori

2015-06-01

Each year, more than 11,000 adolescents and young adults (AYAs), aged 15-34, die from cancer and other life-threatening conditions. In order to facilitate the transition from curative to end-of-life (EoL) care, it is recommended that EoL discussions be routine, begin close to the time of diagnosis, and continue throughout the illness trajectory. However, due largely to discomfort with the topic of EoL and how to approach the conversation, healthcare providers have largely avoided these discussions. We conducted a two-phase study through the National Cancer Institute with AYAs living with cancer or pediatric HIV to assess AYA interest in EoL planning and to determine in which aspects of EoL planning AYAs wanted to participate. These results provided insight regarding what EoL concepts were important to AYAs, as well as preferences in terms of content, design, format, and style. The findings from this research led to the development of an age-appropriate advance care planning guide, Voicing My CHOiCES™. Voicing My CHOiCES™: An Advanced Care Planning Guide for AYA became available in November 2012. This manuscript provides guidelines on how to introduce and utilize an advance care planning guide for AYAs and discusses potential barriers. Successful use of Voicing My CHOiCES™ will depend on the comfort and skills of the healthcare provider. The present paper is intended to introduce the guide to providers who may utilize it as a resource in their practice, including physicians, nurses, social workers, chaplains, psychiatrists, and psychologists. We suggest guidelines on how to: incorporate EoL planning into the practice setting, identify timepoints at which a patient's goals of care are discussed, and address how to empower the patient and incorporate the family in EoL planning. Recommendations for introducing Voicing My CHOiCES™ and on how to work through each section alongside the patient are provided.

The characteristics of abnormal wintertime pollution events in the Jing-Jin-Ji region and its relationships with meteorological factors.

PubMed

Zhu, Wenhui; Xu, Xiangde; Zheng, Jun; Yan, Peng; Wang, Yinjun; Cai, Wenyue

2018-06-01

Despite the implementation of strict air pollution control measures in recent years, severe haze events were still encountered in the Beijing-Tianjin-Hebei (Jing-Jin-Ji) region during the winter 2016. In this work, seasonal differences in correlations between air pollution and geographic terrain, atmospheric dynamical and thermal structures, and PBL height over the Jing-Jin-Ji region in history and recent years were investigated and a comprehensive model of atmospheric factors affecting winter air pollution formation was proposed. We found that the distribution of PM 2.5 concentration closely correlated with the topography feature of China and the difference in haze pollution intensity between winter and other seasons was the most significant in the Jing-Jin-Ji region. The "semi-enclosed" terrain along with the enhanced winter "downdraft" strongly inhibited the diffusion and convection of air pollutants in this region. Meanwhile, seasonal variations of the vertical thermal structure over the Jing-Jin-Ji region, i.e., the anomalous pattern of "upper warming and bottom cooling" structure in the middle troposphere, and the "weak wind zone" were more distinct in winter 2016 than historical record, providing an important precondition for the frequent occurrence of thermal inversion layers and severe pollution episodes in the lower troposphere. In addition, abnormally low PBL heights occurred in the Jing-Jin-Ji region during severe pollutant episodes in winter 2016, with mean postmeridian PBL height in December of only 869.4 m, the minimum value since 2013. PM 2.5 concentration was not only closely related to PBL height but also the "warm cover" structure in the middle troposphere. The stronger the structure was, the lower the PBL height became, and severer the pollution event was encountered, accompanying water vapor accumulation and intensification of the thermal inversion layer in the lower troposphere. All above observations revealed the mutual feedback

Research of Ancient Architectures in Jin-Fen Area Based on GIS&BIM Technology

NASA Astrophysics Data System (ADS)

Jia, Jing; Zheng, Qiuhong; Gao, Huiying; Sun, Hai

2017-05-01

The number of well-preserved ancient buildings located in Shanxi Province, enjoying the absolute maximum proportion of ancient architectures in China, is about 18418, among which, 9053 buildings have the structural style of wood frame. The value of the application of BIM (Building Information Modeling) and GIS (Geographic Information System) is gradually probed and testified in the corresponding fields of ancient architecture’s spatial distribution information management, routine maintenance and special conservation & restoration, the evaluation and simulation of related disasters, such as earthquake. The research objects are ancient architectures in JIN-FEN area, which were first investigated by Sicheng LIANG and recorded in his work of “Chinese ancient architectures survey report”. The research objects, i.e. the ancient architectures in Jin-Fen area include those in Sicheng LIANG’s investigation, and further adjustments were made through authors’ on-site investigation and literature searching & collection. During this research process, the spatial distributing Geodatabase of research objects is established utilizing GIS. The BIM components library for ancient buildings is formed combining on-site investigation data and precedent classic works, such as “Yingzao Fashi”, a treatise on architectural methods in Song Dynasty, “Yongle Encyclopedia” and “Gongcheng Zuofa Zeli”, case collections of engineering practice, by the Ministry of Construction of Qing Dynasty. A building of Guangsheng temple in Hongtong county is selected as an example to elaborate the BIM model construction process based on the BIM components library for ancient buildings. Based on the foregoing work results of spatial distribution data, attribute data of features, 3D graphic information and parametric building information model, the information management system for ancient architectures in Jin-Fen Area, utilizing GIS&BIM technology, could be constructed to support the

[Concepts of "urinary bladder" and "vesicles (bao)" , "jin ye" (fluid and humor) and "urine" and other associated issues].

PubMed

Son, J R; Liu, Y; Ma, Q N; Ju, B Z; Sun, K F; Wu, J D; Zhang, L D; Yang, G L

2017-09-28

In the Huang di nei jing ( Huangdi ' s Internal Classic ), jin ye (fluid and humor) is described in two senses, broad and narrow, though not so strictly.Sometimes, jin ye is explained ambiguously as "sweat" and "urine" , as in the phrase "the bladder, being a house of jin ye " , here " jin ye " refers to the urine. In the Qi jue lun pian of Su wen ( Chapter on Qi - Syncope of Plain Questions ) , the " bao " in the sentence "heat of bao moved to bladder" refersto the uterus. In the Shi cong rong lun pian ( Chapter of Readily Inspecting ) of Plain Questions , the "bladder" in the phrase "gallbladder, stomach, large intestine, small intestine, spleen, bao and bladder" , which, being an annotation of " bao " originally, is mistakenly incorporated into the text of the Classic . In the Wu wei lun of Ling shu ( On Five Tastes in Miraculous Pivot ) , the " bao " in " bao of bladder" refers to the external hou (external manifestation) of the bladder, that is the scrotum. In the Bei ji qian jin yao fang ( Essential Prescriptions Worth a Thousand Gold for Emergencies ) , the short sentence " pang guang zou bao " is an error in itself. In the sentence of "settled in the bao and zhi causing to dream of defecation and urination" in the Yin xie fa meng (Dreams due to Evils) of Miraculous Pivot , " bao " refers to uterus, and " zhi " to anus. In Bi lun pian ( Chapter on Impediment ) of Plain Questions , "the man suffered bao bimight feel internal pain when the lesser abdomen and bladder are pressed" , here, " bao " refers to the bladder. In the Wu yin wu wei ( Chapter on Five Sound and Five Tastes ) of Miraculous Pivot , the " bao " in the sentence "thoroughfare vessel and conception vessel all starts from bao " , again, " bao " here refers to the bladder, rather than to the uterus. From the above descriptions of "bladder" and " bao " in the Huangdi ' s Internal Classic , the "bladder" in ancient medical books refers to the substantial bladder, an anatomical organ, and " bao

The impact of new transportation modes on population distribution in Jing-Jin-Ji region of China

PubMed Central

Wang, Lizhe; Chen, Lajiao

2018-01-01

This paper conducts a novel study in China’s Jing-Jin-Ji region to investigate the determinants of population distribution and short-term migration based on a comprehensive dataset including traditional census data, earth observation data, and emerging Internet data. Our results show that due to the high level of urbanization in this region, natural conditions are no longer the strongest determinants of population distribution. New transportation modes, such as high-speed rail, have arisen as a significant determinant of population distribution and short-term migration, particularly in large cities. Socio-economic factors such as GDP, investment, urbanization level, and technology, which are traditionally assumed to govern population distribution and short-term migration, have less influence although education still remains an important factor affecting population distribution. These findings will contribute valuable information to regional planning decision-making in the Jing-Jin-Ji region. PMID:29360105

Phytoavailability of Cadmium (Cd) to Pak Choi (Brassica chinensis L.) Grown in Chinese Soils: A Model to Evaluate the Impact of Soil Cd Pollution on Potential Dietary Toxicity

PubMed Central

Yang, Xiaoe; Xiao, Wendan; Stoffella, Peter J.; Saghir, Aamir; Azam, Muhammad; Li, Tingqiang

2014-01-01

Food chain contamination by soil cadmium (Cd) through vegetable consumption poses a threat to human health. Therefore, an understanding is needed on the relationship between the phytoavailability of Cd in soils and its uptake in edible tissues of vegetables. The purpose of this study was to establish soil Cd thresholds of representative Chinese soils based on dietary toxicity to humans and develop a model to evaluate the phytoavailability of Cd to Pak choi (Brassica chinensis L.) based on soil properties. Mehlich-3 extractable Cd thresholds were more suitable for Stagnic Anthrosols, Calcareous, Ustic Cambosols, Typic Haplustalfs, Udic Ferrisols and Periudic Argosols with values of 0.30, 0.25, 0.18, 0.16, 0.15 and 0.03 mg kg−1, respectively, while total Cd is adequate threshold for Mollisols with a value of 0.86 mg kg−1. A stepwise regression model indicated that Cd phytoavailability to Pak choi was significantly influenced by soil pH, organic matter, total Zinc and Cd concentrations in soil. Therefore, since Cd accumulation in Pak choi varied with soil characteristics, they should be considered while assessing the environmental quality of soils to ensure the hygienically safe food production. PMID:25386790

Phytoavailability of cadmium (Cd) to Pak choi (Brassica chinensis L.) grown in Chinese soils: a model to evaluate the impact of soil Cd pollution on potential dietary toxicity.

PubMed

Rafiq, Muhammad Tariq; Aziz, Rukhsanda; Yang, Xiaoe; Xiao, Wendan; Stoffella, Peter J; Saghir, Aamir; Azam, Muhammad; Li, Tingqiang

2014-01-01

Food chain contamination by soil cadmium (Cd) through vegetable consumption poses a threat to human health. Therefore, an understanding is needed on the relationship between the phytoavailability of Cd in soils and its uptake in edible tissues of vegetables. The purpose of this study was to establish soil Cd thresholds of representative Chinese soils based on dietary toxicity to humans and develop a model to evaluate the phytoavailability of Cd to Pak choi (Brassica chinensis L.) based on soil properties. Mehlich-3 extractable Cd thresholds were more suitable for Stagnic Anthrosols, Calcareous, Ustic Cambosols, Typic Haplustalfs, Udic Ferrisols and Periudic Argosols with values of 0.30, 0.25, 0.18, 0.16, 0.15 and 0.03 mg kg-1, respectively, while total Cd is adequate threshold for Mollisols with a value of 0.86 mg kg-1. A stepwise regression model indicated that Cd phytoavailability to Pak choi was significantly influenced by soil pH, organic matter, total Zinc and Cd concentrations in soil. Therefore, since Cd accumulation in Pak choi varied with soil characteristics, they should be considered while assessing the environmental quality of soils to ensure the hygienically safe food production.

Theories, Evidence and Intuitions about Infants' Attributions of Goals: A Reply to Commentaries by Biro and Kuhlmeier & Robson and Luo & Choi

ERIC Educational Resources Information Center

Hernik, Mikolaj; Southgate, Victoria

2012-01-01

This reply article is to be published alongside: Hernik, M., & Southgate, V. (2012). This is a response to the commentaries on Hernik and Southgate (2012) by Biro (2012), Kuhlmeier and Robson (2012) and Luo and Choi (2012). Both L&C and K&R reject the authors' conclusion that an absence of a Woodward-effect in some single-object versions of the…

Detecting the causality influence of individual meteorological factors on local PM2.5 concentration in the Jing-Jin-Ji region

NASA Astrophysics Data System (ADS)

Chen, Ziyue; Cai, Jun; Gao, Bingbo; Xu, Bing; Dai, Shuang; He, Bin; Xie, Xiaoming

2017-01-01

Due to complicated interactions in the atmospheric environment, quantifying the influence of individual meteorological factors on local PM2.5 concentration remains challenging. The Beijing-Tianjin-Hebei (short for Jing-Jin-Ji) region is infamous for its serious air pollution. To improve regional air quality, characteristics and meteorological driving forces for PM2.5 concentration should be better understood. This research examined seasonal variations of PM2.5 concentration within the Jing-Jin-Ji region and extracted meteorological factors strongly correlated with local PM2.5 concentration. Following this, a convergent cross mapping (CCM) method was employed to quantify the causality influence of individual meteorological factors on PM2.5 concentration. The results proved that the CCM method was more likely to detect mirage correlations and reveal quantitative influences of individual meteorological factors on PM2.5 concentration. For the Jing-Jin-Ji region, the higher PM2.5 concentration, the stronger influences meteorological factors exert on PM2.5 concentration. Furthermore, this research suggests that individual meteorological factors can influence local PM2.5 concentration indirectly by interacting with other meteorological factors. Due to the significant influence of local meteorology on PM2.5 concentration, more emphasis should be given on employing meteorological means for improving local air quality.

Glutamine nitrogen and ammonium nitrogen supplied as a nitrogen source is not converted into nitrate nitrogen of plant tissues of hydroponically grown pak-choi (Brassica chinensis L.).

PubMed

Wang, H-J; Wu, L-H; Tao, Q-N; Miller, D D; Welch, R M

2009-03-01

Many vegetables, especially leafy vegetables, accumulate NO(-) (3)-N in their edible portions. High nitrate levels in vegetables constitute a health hazard, such as cancers and blue baby syndrome. The aim of this study was to determine if (1) ammonium nitrogen (NH(+) (4)-N) and glutamine-nitrogen (Gln-N) absorbed by plant roots is converted into nitrate-nitrogen of pak-choi (Brassica chinensis L.) tissues, and (2) if nitrate-nitrogen (NO(-) (3)-N) accumulation and concentration of pak-choi tissues linearly increase with increasing NO(-) (3)-N supply when grown in nutrient solution. In experiment 1, 4 different nitrogen treatments (no nitrogen, NH(+) (4)-N, Gln-N, and NO(-) (3)-N) with equal total N concentrations in treatments with added N were applied under sterile nutrient medium culture conditions. In experiment 2, 5 concentrations of N (from 0 to 48 mM), supplied as NO(-) (3)-N in the nutrient solution, were tested. The results showed that Gln-N and NH(+) (4)-N added to the nutrient media were not converted into nitrate-nitrogen of plant tissues. Also, NO(-) (3)-N accumulation in the pak-choi tissues was the highest when plants were supplied 24 mM NO(-) (3)-N in the media. The NO(-) (3)-N concentration in plant tissues was quadratically correlated to the NO(-) (3)-N concentration supplied in the nutrient solution.

The Impact of Land Use and Land Cover Change on Water Yield in the Jing- Jin-Ji Region in China

NASA Astrophysics Data System (ADS)

Li, Suxiao; Yang, Hong

2017-04-01

Water yield is one of the key ecosystem services sustaining both people's life and economic development. However, the water yield function is sensitive to anthropogenic activity especially the land use and land cover change (LUCC). Assessment of historical LUCC and its impact on water yield could benefit designing and implementing appropriate land use strategy that enhance the water yield capacity. Beijing (Jing) and its surrounding areas of Tianjin (Jin) and Hebei (Ji) is the political, cultural and economic center of China. The region is facing increasingly water crisis. Taking the Jing-Jin-Ji region as a study area, this study analyzed the historical LUCC and its impact on water yield by using the Integrated Valuation of Ecosystem Services and Tradeoffs (InVEST) model to spatially map and quantify the changes of water yield from 1995 to 2010. The results showed there was main decline in area of wetland and forest and increase in area of crop land and built up land. An abrupt decline in water yield was found for year 2000. The water yield was influenced to a great extent by precipitation and evapotranspiration, but the land use played an important role in the water yield capacity (water yield per unit area) through plant cover that affected evapotranspiration, soil water permeability and the capacity of holding the moisture content. By general ranking, the water yield capacity of different land use type was as follows: built-up>bare land>cropland> grassland>forest >wetland, which illustrated that the built-up and bare land had higher run off rate while the vegetation area had higher capacity to control surface run off to increase the groundwater. A good understanding of temporal-spatial allocation of historical LUCC and Water yield of the Jing-Jin-Ji region could help guide land use policy decisions that take into consideration of tradeoffs with respect to spatial distribution of ecosystem services amongst the three administrative entities (Jing-Jin-Ji) and

[Evaluation on efficacy of Jin's "Sanzhen" therapy combined with rehabilitation training for hemiplegia of stroke patients by Fugl-Meyer scale].

PubMed

Han, De-Xiong; Zhuang, Li-Xing; Zhang, Ying

2011-06-01

To assess the therapeutic effect of Jin's "Sanzhen" therapy combined with rehabilitation training on limb-motor function of stroke patients by using Fugl-Meyer scale. A total of 254 hemiplegic stroke outpatients and inpatients from 7 hospitals were randomly divided into Jin's "Sanzhen" (JSZ) group (n = 83), rehabilitation group (n = 84) and combination group (n = 87). Acupuncture was applied to acupoints of Jin's "Sanzhen" including Quchi (LI 11), Waiguan (SJ 5) and Hegu (LI 4); Futu (ST 32). Zusanli (ST 36) and Sanyinjiao (SP 6); etc. The acupuncture needles were retained for 30 min after "Deqi". Rehabilitation training included passive joint movement, standing-sitting training, tapping-pressing stimulation, walking training, etc. The treatment was conducted once daily, 5 sessions a week and for 4 weeks. Fugl-Meyer scale composed of 100-point motor domain of the upper- and lower-extremity sections was used to assess the patients' motor function. On day 28 after the treatment, of the 83.84 and 87 hemiplegic stroke patients in the JSZ, rehabilitation and combination groups, 48 (57.8%), 31 (36.9%) and 50 (57.5%) experienced marked improvement in their clinical symptoms and signs, 26 (31.3%), 44 (52.4%) and 31(35.6%) had an improvement, and 9 (10.8%), 9 (10.7%) and 6 (6.9%) failed in the treatment, with the total effective rates being 89.2%, 89.3% and 93.1%, respectively. The neurological deficit score (NDS) of the combination group was significantly lower than that of the rehabilitation group (P < 0.05). The Fugl-Meyer assessment score (FMAS) for extremity motor function of the combination group was apparently higher than those of the JSZ and rehabilitation groups (P < 0.05). No significant differences were found between the JSZ and rehabilitation groups in both NDS and FMAS (P > 0.05). Jin's "Sanzhen" therapy combined with rehabilitation training can significantly improve the limb motor function of hemiplegic stroke patients, and has a good synergistic effect.

The impact of the "Air Pollution Prevention and Control Action Plan" on PM2.5 concentrations in Jing-Jin-Ji region during 2012-2020.

PubMed

Cai, Siyi; Wang, Yangjun; Zhao, Bin; Wang, Shuxiao; Chang, Xing; Hao, Jiming

2017-02-15

In order to cope with heavy haze pollution in China, the Air Pollution Prevention and Control Action Plan including phased goals of the fine particulate matter (PM 2.5 ) was issued in 2013. In this study, China's emission inventories in the baseline 2012 and the future scenarios of 2017 and 2020 have been developed based on this Action Plan. Beijing-Tianjin-Hebei (Jing-Jin-Ji) region, one of the most polluted regions in China, was taken as a case to assess the impact of phased emission control measures on PM 2.5 concentration reduction using WRF-CMAQ model system. With the implementation of the Action Plan, the emissions of sulfur dioxide (SO 2 ), nitrogen oxides (NO X ) , PM 2.5 , non-methane volatile organic compound (NMVOC), and ammonia (NH 3 ) in 2017 will decrease by36%, 31%, 30%,12%, and -10% from the 2012 levels in Jing-Jin-Ji, respectively. In 2020, the emissions of SO 2 , NO X, PM 2.5 , NMVOC, and NH 3 will decrease by 40%, 44%, 40%, 22%, and -3% from the 2012 levels in Jing-Jin-Ji, respectively. Consequently, the ambient annual PM 2.5 concentration under the scenarios of 2017 and 2020 will be 28.3% and 37.8% lower than those in 2012, respectively. The Action Plan provided an effective approach to alleviate PM 2.5 pollution level in Jing-Jin-Ji region. However, emission control of NMVOC and NH 3 should be paid more attention and be strengthened in future. Meanwhile, emission control of NO x , SO 2 , NH 3 and NMVOC synergistically are highly needed in the future because multiple pollutants impact on PM 2.5 and O 3 concentrations nonlinearly. Copyright © 2016 Elsevier B.V. All rights reserved.

Author's Rebuttal to Smits et al. (2018), "Comment on 'Sensitivity of the Speech Intelligibility Index to the Assumed Dynamic Range' by Jin et al. (2017)".

PubMed

Jin, In-Ki; Kates, James M; Arehart, Kathryn H

2018-01-22

The purpose of this letter is to refute the comments written by Smits, Goverts, and Versfeld (2018). Refutations to each issue including the fixed mathematical relationship between dynamic range (DR) and a fitting constant (Q value), deviating results for small DRs, and determination of Speech Intelligibility Index (SII) model parameters are described. Although Smits et al. (2018) correctly identified several issues, those comments do not diminish the results of the original article (Jin, Kates, & Arehart, 2017) in providing new insights for the SII. Jin et al. (2017) clearly provided the impact of languages and DR on the SII, which was the main result of the study.

Comparative effects of Yi Jin Jing versus Tai Chi exercise training on benign prostatic hyperplasia-related outcomes in older adults: study protocol for a randomized controlled trial.

PubMed

Liu, XiangYun; Huang, Guoyuan; Chen, Peijie; Li, Yong; Xiang, JiuLin; Chen, Ting; Wang, Ru

2016-07-16

Benign prostatic hyperplasia (BPH) and its associated lower urinary tract symptoms (LUTS) occur very commonly in older men. BPH and LUTS cause substantial physical and psychological impairment that could seriously affect the quality of late life and greatly cost the health-care systems. Current surgical and pharmacological therapies are expensive, may not effectively improve prostate function and health but cause adverse effects. There is an urgent need to find new and effective non-pharmacological preventions and treatments. Yi Jin Jing and Tai Chi are two common traditional Chinese mind-body exercises with different movements and techniques, but both emphasize regulating functional homeostasis and keeping whole body harmony. Yi Jin Jing and Tai Chi have not been studied much for potentially use in the treatment of BPH-related problems. The primary purpose of this protocol is to assess the effectiveness of Yi Jin Jing versus Tai Chi on the monographic and functional changes of prostate in older men. A prospective single-center randomized controlled trial will be conducted. A total of 150 old men (60-70 years old) will be recruited from the urban tertiary of Shanghai, China. Of these, 50 eligible participants will be randomly assigned to a control group and two intervention groups with either Yi Jin Jing or Tai Chi exercise training. They will undergo 30 minutes for each exercise for five times a week for 6 months. The primary outcomes are changes of signs and symptoms in BPH and lower urinary tract from baseline to post-intervention. The main secondary outcomes are exercise-induced effects on the circulating levels of estrogen and androgen. All the outcome measures will be assessed at baseline, immediately after the 6-month intervention, and at the 3-month post-intervention follow-up. This proposed study will be the first comparative randomized clinical trial to evaluate the effectiveness of Yi Jin Jing versus Tai Chi exercise on prostate health among older

Consumption-based Total Suspended Particulate Matter Emissions in Jing-Jin-Ji Area of China

NASA Astrophysics Data System (ADS)

Yang, S.; Chen, S.; Chen, B.

2014-12-01

The highly-industrialized regions in China have been facing a serious problem of haze mainly consisted of total suspended particulate matter (TSPM), which has attracted great attention from the public since it directly impairs human health and clinically increases the risks of various respiratory and pulmonary diseases. In this paper, we set up a multi-regional input-output (MRIO) model to analyze the transferring routes of TSPM emissions between regions through trades. TSPM emission from particulate source regions and sectors are identified by analyzing the embodied TSPM flows through monetary flow and carbon footprint. The track of TSPM from origin to end via consumption activities are also revealed by tracing the product supply chain associated with the TSPM emissions. Beijing-Tianjin-Hebei (Jing-Jin-Ji) as the most industrialized area of China is selected for a case study. The result shows that over 70% of TSPM emissions associated with goods consumed in Beijing and Tianjin occurred outside of their own administrative boundaries, implying that Beijing and Tianjin are net embodied TSPM importers. Meanwhile, 63% of the total TSPM emissions in Hebei Province are resulted from the outside demand, indicating Hebei is a net exporter. In addition, nearly half of TSPM emissions are the by-products related to electricity and heating supply and non-metal mineral products in Jing-Jin-Ji Area. Based on the model results, we provided new insights into establishing systemic strategies and identifying mitigation priorities to stem TSPM emissions in China. Keywords: total suspended particulate matter (TSPM); urban ecosystem modeling; multi-regional input-output (MRIO); China

"Not just a theory": the relationship between Jin Shin Jyutsu® self-care training for nurses and stress, physical health, emotional health, and caring efficacy.

PubMed

Lamke, Donna; Catlin, Anita; Mason-Chadd, Michelle

2014-12-01

The purpose of this study was to evaluate the effect of training nurses in Jin Shin Jyutsu® self-care methods and to correlate the training with measurement of the nurses' personal and organizational stress and their perceptions of their caring efficacy for patients. A quasi-experimental, pretest, posttest, and 30- to 40-day posttest design was used. In all, 20 participants received three 2-hour Jin Shin Jyutsu self-care training sessions from a certified Jin Shin Jyutsu self-care trainer (who was also a registered nurse). The training took place over a 1-month period, and participants agreed to practice the self-care daily. Two study instruments, one measuring organizational and personal stress and the second measuring caring efficacy, were completed before the first training, after the last training, and 1 month after the trainings had been completed. Analysis of data from the Personal and Organizational Quality Assessment-Revised by paired t tests showed significant increases in positive outlook, gratitude, motivation, calmness, and communication effectiveness and significant decreases in anger, resentfulness, depression, stress symptoms, time pressure, and morale issues. Nurses reported less muscle aches, sleeplessness, and headaches. Analysis of the Coates Caring Efficacy Scale measures showed statistically significant increases in nurses' caring efficacy in areas of serenity in giving care, tuning in to patients, relating to patients, providing culturally congruent care, individualization of patient care, ability to decrease stressful situations, planning for multiple needs, and creativity in care. This small study suggests that Jin Shin Jyutsu self-care may be a valuable tool for nurses, to decrease stress, both emotional and physical, and increase caring efficacy. Administrators may wish to invest in such a program, which may improve quality of care delivered. The Watson caring model, which reminds us that nurses who care for themselves and feel good about

SDE and SPME Analysis of Flavor Compounds in Jin Xuan Oolong Tea.

PubMed

Sheibani, Ershad; Duncan, Susan E; Kuhn, David D; Dietrich, Andrea M; O'Keefe, Sean F

2016-02-01

Simultaneous distillation-extraction (SDE) and solid phase micro extraction (SPME) are procedures used for the isolation of flavor compounds in foods. The purpose of this study was to optimize SDE conditions (solvent and time) and to compare SDE with SPME for the isolation of flavor compounds in Jin Xuan oolong tea using GC-MS and GC-O. The concentration of volatile compounds isolated with diethyl ether was higher (P < 0.05) than for dichloromethane and concentration was higher at 40 min (P < 0.05) than 20 or 60 min extractions. For SDE, 128 volatiles were identified using GC-MS and 45 aroma active compounds using GC-O. Trans-nerolidol was the most abundant compound in oolong tea. The number of volatiles identified using GC-MS was lower in SPME than SDE. For SPME, 59 volatiles and 41 aroma active compounds were identified. The composition of the volatiles isolated by the 2 methods differed considerably but provided complementary information. © 2016 Institute of Food Technologists®

Impact of different feedstocks derived biochar amendment with cadmium low uptake affinity cultivar of pak choi (Brassica rapa ssb. chinensis L.) on phytoavoidation of Cd to reduce potential dietary toxicity.

PubMed

Yasmin Khan, Kiran; Ali, Barkat; Cui, Xiaoqiang; Feng, Ying; Yang, Xiaoe; Joseph Stoffella, Peter

2017-07-01

Biochar has become eco-friendly amendment used for phytoavoidation with low cadmium (Cd) accumulating cultivars of crops to ensure food safety in Cd contaminated soils. In this study, biochar with different waste feedstock material were evaluated for their effectiveness on essential trace metals mobility, Cd bioavailability and its accumulation in two contrasting Cd accumulating cultivars of pak choi (Brassica rapa ssp. chinensis L.) grown in Cd contaminated Mollisol soil. A greenhouse experiment was conducted with plants grown in Cd contaminated soil that had been amended with biochar derived from barley straw, tomato green waste, chicken manure, duck manure and swine manure at application rate of 0%, 2.5% and 5.0% (w/w). The results showed that soil pH was significantly increased by all treatments. Biochar increased plant dry biomass, micronutrients bioavailability with significant differences in the Cd sorption capacity, with the effectiveness higher with increasing biochar application rate. However, tomato green waste (TGW) and chicken manure (CM) derived biochar were more effective than the other biochar in reducing Cd mobilization in soil by 35-54% and 26-43% and reduced its accumulation in shoots of pak choi cultivars by 34-76% and 33-72% in low Cd accumulator cultivar and 64-85% and 55-80% in high Cd accumulator cultivar than the control. Overall, results indicate that TGW and CM biochar can efficiently immobilize Cd, thereby reducing bioavailability in Cd contaminated Mollisol soil to ensure food safety. Copyright © 2017 Elsevier Inc. All rights reserved.

Jin Fu Kang Oral Liquid Inhibits Lymphatic Endothelial Cells Formation and Migration

PubMed Central

Wang, Dan; Tang, Jie

2016-01-01

Lung cancer is the leading cause of cancer-related deaths worldwide. Jin Fu Kang (JFK), an oral liquid prescription of Chinese herbal drugs, has been clinically available for the treatment of non-small cell lung cancer (NSCLC). Lymphangiogenesis is a primary event in the process of cancer development and metastasis, and the formation and migration of lymphatic endothelial cells (LECs) play a key role in the lymphangiogenesis. To assess the activity of stromal cell-derived factor-1 (SDF-1) and the coeffect of SDF-1 and vascular endothelial growth factor-C (VEGF-C) on the formation and migration of LECs and clarify the inhibitory effects of JFK on the LECs, the LECs were differentiated from CD34+/VEGFR-3+ endothelial progenitor cells (EPCs), and JFK-containing serums were prepared from rats. SDF-1 and VEGF-C both induced the differentiation of CD34+/VEGFR-3+ EPCs towards LECs and enhanced the LECs migration. Couse of SDF-1 and VEGF-C displayed an additive effect on the LECs formation but not on their migration. JFK inhibited the formation and migration of LECs, and the inhibitory effects were most probably via regulation of the SDF-1/CXCR4 and VEGF-C/VEGFR-3 axes. The current finding suggested that JFK might inhibit NSCLC through antilymphangiogenesis and also provided a potential to discover antilymphangiogenesis agents from natural resources. PMID:27698675

Jin Fu Kang Oral Liquid Inhibits Lymphatic Endothelial Cells Formation and Migration.

PubMed

He, Hai-Lang; Wang, Dan; Tang, Jie; Zhou, Xian-Mei; Li, Jian-Xin; Xu, Ling

2016-01-01

Lung cancer is the leading cause of cancer-related deaths worldwide. Jin Fu Kang (JFK), an oral liquid prescription of Chinese herbal drugs, has been clinically available for the treatment of non-small cell lung cancer (NSCLC). Lymphangiogenesis is a primary event in the process of cancer development and metastasis, and the formation and migration of lymphatic endothelial cells (LECs) play a key role in the lymphangiogenesis. To assess the activity of stromal cell-derived factor-1 (SDF-1) and the coeffect of SDF-1 and vascular endothelial growth factor-C (VEGF-C) on the formation and migration of LECs and clarify the inhibitory effects of JFK on the LECs, the LECs were differentiated from CD34 + /VEGFR-3 + endothelial progenitor cells (EPCs), and JFK-containing serums were prepared from rats. SDF-1 and VEGF-C both induced the differentiation of CD34 + /VEGFR-3 + EPCs towards LECs and enhanced the LECs migration. Couse of SDF-1 and VEGF-C displayed an additive effect on the LECs formation but not on their migration. JFK inhibited the formation and migration of LECs, and the inhibitory effects were most probably via regulation of the SDF-1/CXCR4 and VEGF-C/VEGFR-3 axes. The current finding suggested that JFK might inhibit NSCLC through antilymphangiogenesis and also provided a potential to discover antilymphangiogenesis agents from natural resources.

Development and Validation of an UPLC-MS/MS Method for Pharmacokinetic Comparison of Five Alkaloids from JinQi Jiangtang Tablets and Its Monarch Drug Coptidis Rhizoma

PubMed Central

Sun, Lili; Ding, Feifei; You, Guangjiao; Liu, Han; Wang, Meng; Ren, Xiaoliang; Deng, Yanru

2017-01-01

JinQi Jiangtang (JQJT) tablets, a Chinese patent medicine approved by the State Food and Drug Administration, are composed of Coptidis Rhizoma, Astragali Radix, and Lonicerae Japonicae Flos, and have a significant effect on diabetes. Coptidis Rhizoma is monarch drug in the prescription. The aim of the present study was to investigate and compare the pharmacokinetics of multiple ingredients from JQJT tablets and Coptidis Rhizoma extract (CRE) following oral administration in rats. Five alkaloids: coptisine chloride, epiberberine chloride, berberine chloride, jatrorrhizine chloride, and palmatine chloride, were simultaneously determined in rat plasma using established and validated ultra-high performance liquid chromatography mass spectrometry (UPLC-MS/MS). Significant pharmacokinetic differences were observed for the five alkaloids after a single administration of CRE and JQJT tablets. Compared with CRE, the Cmax values of palmatine chloride and jatrorrhizine chloride were decreased significantly, the AUC0–t values of four alkaloids (all except jatrorrhizine chloride) were notably decreased, and the mean residence times of all five alkaloids were significantly decreased after administration of JQJT tablets. The results indicated that the absorption characteristics of the five alkaloids from Coptidis Rhizoma would be influenced by the compatibility of Astragali Radix or Lonicerae Japonicae Flos from JQJT tablets, such that absorption was inhibited and elimination was accelerated. In conclusion, the developed strategy was suitable for the comparison of five alkaloids from JinQi Jiangtang tablets and its monarch drug, which could be valuable for compatibility studies of traditional Chinese medicines. PMID:29286316

Simultaneous quantification of five major active components in capsules of the traditional Chinese medicine ‘Shu-Jin-Zhi-Tong’ by high performance liquid chromatography

PubMed Central

Yang, Xing-Xin; Zhang, Xiao-Xia; Chang, Rui-Miao; Wang, Yan-Wei; Li, Xiao-Ni

2011-01-01

A simple and reliable high performance liquid chromatography (HPLC) method has been developed for the simultaneous quantification of five major bioactive components in ‘Shu-Jin-Zhi-Tong’ capsules (SJZTC), for the purposes of quality control of this commonly prescribed traditional Chinese medicine. Under the optimum conditions, excellent separation was achieved, and the assay was fully validated in terms of linearity, precision, repeatability, stability and accuracy. The validated method was applied successfully to the determination of the five compounds in SJZTC samples from different production batches. The HPLC method can be used as a valid analytical method to evaluate the intrinsic quality of SJZTC. PMID:29403711

A novel cold-inducible gene from Pak-choi (Brassica campestris ssp. chinensis), BcWRKY46, enhances the cold, salt and dehydration stress tolerance in transgenic tobacco.

PubMed

Wang, Feng; Hou, Xilin; Tang, Jun; Wang, Zhen; Wang, Shuming; Jiang, Fangling; Li, Ying

2012-04-01

WRKY TFs belong to one of the largest families of transcriptional regulators in plants and form integral parts of signaling webs that modulate many plant processes. BcWRKY46, a cDNA clone encoding a polypeptide of 284 amino acids and exhibited the structural features of group III of WRKY protein family, was isolated from the cold-treated leaves of Pak-choi (Brassica campestris ssp. chinensis Makino, syn. B. rapa ssp. chinensis) using the cDNA-AFLP technique. Expression of this gene was induced quickly and strongly in response to various environmental stresses, including low temperatures, ABA, salt and dehydration. Constitutive expression of BcWRKY46 in tobacco under the control of the CaMV35S promoter reduced the susceptibility of transgenic tobacco to freezing, ABA, salt and dehydration stresses. Our studies suggest that BcWRKY46 plays an important role in responding to ABA and abiotic stress.

Traditional Chinese medicine compound ShengJinRunZaoYangXue granules for treatment of primary Sjögren's syndrome: a randomized, double-blind, placebo-controlled clinical trial.

PubMed

Hu, Wei; Qian, Xian; Guo, Feng; Zhang, Miaojia; Lyu, Chengyin; Tao, Juan; Gao, Zhong'en; Zhou, Zhengqiu

2014-01-01

Traditional Chinese medical treatment of primary Sjögren's syndrome has advantages over Western medicine in terms of fewer side effects and improved patient conditions. This study was a multicenter, randomized, double-blind, placebo-controlled clinical trial of the efficacy and safety of ShengJinRunZaoYangXue granules for the treatment of primary Sjögren's syndrome, including the symptoms of dry mouth and dry eye. We undertook a 6-week, double-blind, randomized trial involving 240 patients with primary Sjögren's syndrome at five centers in East China. A computer-generated randomization schedule assigned patients at a 2:1 ratio to receive either ShengJinRunZaoYangXue granules or placebo once daily. Patients and investigators were blinded to treatment allocation. The primary endpoints were the salivary flow rate, Schirmer test results, and sugar test results. Intention-to-treat and per-protocol analyses were performed. All 240 patients were randomly allocated to either the treatment group (n = 160, ShengJinRunZaoYangXue granules) or placebo group (n = 80) and were included in the intention-to-treat analysis. After program violation and loss to follow-up, a total of 199 patients were included in the per-protocol analysis. At six week, intention-to-treat and per-protocol analyses of the left-eye Schirmer I test results showed an improved difference of 1.36 mm/5 min (95% CI: 0.03 to 2.69 mm/5 min) and 1.35 mm/5 min (95% CI: 0.04 to 2.73 mm/5 min), respectively, and those of the right-eye Schirmer I test results showed an improved difference of 1.12 mm/5 min (95% CI: 0.02 to 2.22 mm/5 min) and 1.12 mm/5 min (95% CI: -0.02 to 2.27 mm/5 min), respectively. There was no significant difference between the two groups before treatment. After treatment, the between-group and within-group before-and-after paired comparison results were statistically significant (P < 0.05). Intention-to-treat and per-protocol analyses showed an improved salivary flow rate by 0.04 ml/15 min (95

Space-time PM2.5 mapping in the severe haze region of Jing-Jin-Ji (China) using a synthetic approach.

PubMed

He, Junyu; Christakos, George

2018-05-07

Long- and short-term exposure to PM 2.5 is of great concern in China due to its adverse population health effects. Characteristic of the severity of the situation in China is that in the Jing-Jin-Ji region considered in this work a total of 2725 excess deaths have been attributed to short-term PM 2.5 exposure during the period January 10-31, 2013. Technically, the processing of large space-time PM 2.5 datasets and the mapping of the space-time distribution of PM 2.5 concentrations often constitute high-cost projects. To address this situation, we propose a synthetic modeling framework based on the integration of (a) the Bayesian maximum entropy method that assimilates auxiliary information from land-use regression and artificial neural network (ANN) model outputs based on PM 2.5 monitoring, satellite remote sensing data, land use and geographical records, with (b) a space-time projection technique that transforms the PM 2.5 concentration values from the original spatiotemporal domain onto a spatial domain that moves along the direction of the PM 2.5 velocity spread. An interesting methodological feature of the synthetic approach is that its components (methods or models) are complementary, i.e., one component can compensate for the occasional limitations of another component. Insight is gained in terms of a PM 2.5 case study covering the severe haze Jing-Jin-Ji region during October 1-31, 2015. The proposed synthetic approach explicitly accounted for physical space-time dependencies of the PM 2.5 distribution. Moreover, the assimilation of auxiliary information and the dimensionality reduction achieved by the synthetic approach produced rather impressive results: It generated PM 2.5 concentration maps with low estimation uncertainty (even at counties and villages far away from the monitoring stations, whereas during the haze periods the uncertainty reduction was over 50% compared to standard PM 2.5 mapping techniques); and it also proved to be computationally very

The cost-effectiveness analysis of JinQi Jiangtang tablets for the treatment on prediabetes: a randomized, double-blind, placebo-controlled, multicenter design.

PubMed

Sun, Xiao; Guo, Liping; Shang, Hongcai; Ren, Ming; Wang, Yue; Huo, Da; Lei, Xiang; Wang, Hui; Zhai, Jingbo

2015-11-03

reduced the incidence of diabetes mellitus and enhanced reversion rate. compared with the control group (p< 0.05); the scores of SF-36 of two groups had no significant difference P> 0.05); finally the compliance of participants between the two groups had no significant difference. The cost-effectiveness analysis outcomes:in the intervention period of 12 months,on the aspect of reversion rate, the treatment group had better economic advantage by using cost-effectiveness ratio and the incremental cost-effectiveness ratio;on the aspect of the incidence of diabetes, the control group had better economic advantage by using cost-effectiveness ratio and the incremental cost-effectiveness ratio; in the follow-up period of 24 months, on the aspect of reversion rate, the treatment group had better economic advantage by using cost-effectiveness ratio and the incremental cost-effectiveness ratio, on the aspect of the incidence of diabetes, the control group had better economic advantage by using cost-effectivenes ratio and the incremental cost-effectiveness ratio.At the same time, these outcomes remained the same by sensitivity analysis. Assuming that prices and resident incomes rose 5%, the sensitiveness analysis shows that the two group affected by the paremeters changed little. The importance and effectiveness of lifestyle education and JinQi Jiangtang tablets was proven. In both the intervention period and follow-up, JinQi Jiangtang tablets combined with lifestyle education had a greater cost advantage effect than the lifestyle education alone on the reversion rate; the lifestyle education had a greater cost advantage effect than the JinQi Jiangtang tablets combined with lifestyle education on the incidence of diabetes. Chinese Clinical Trials ChiCTR-TRC-09000401 ) , registered on 25 May 2009.

Study protocol of the CHOiCE trial: a three-armed, randomized, controlled trial of home-based HPV self-sampling for non-participants in an organized cervical cancer screening program.

PubMed

Tranberg, Mette; Bech, Bodil Hammer; Blaakær, Jan; Jensen, Jørgen Skov; Svanholm, Hans; Andersen, Berit

2016-11-03

The effectiveness of cervical cancer screening programs is challenged by suboptimal participation and coverage. Offering cervico-vaginal self-sampling for human papillomavirus testing (HPV self-sampling) to non-participants can increase screening participation. However, the effect varies substantially among studies, especially depending on the approach used to offer HPV self-sampling. The present trial evaluates the effect on participation in an organized screening program of a HPV self-sampling kit mailed directly to the home of the woman or mailed to the woman's home on demand only, compared with the standard second reminder for regular screening. The CHOiCE trial is a parallel, randomized, controlled, open-label trial. It will include 9327 women aged 30-64 years who are living in the Central Denmark Region and who have not participated in cervical cancer screening after an invitation and one reminder. The women will be equally randomized into three arms: 1) Directly mailed a second reminder including a HPV self-sampling kit; 2) Mailed a second reminder offering a HPV self-sampling kit, to be ordered by e-mail, text message, phone, or through a webpage; and 3) Mailed a second reminder for a practitioner-collected sample (control group). The primary outcome will be the proportion of women in the intervention groups who participate by returning their HPV self-sampling kit or have a practitioner-collected sample compared with the proportion of women who have a practitioner-collected sample in the control group at 90 and 180 days after mail out of the second reminders. Per-protocol and intention-to-treat analyses will be performed. The secondary outcome will be the proportion of women with a positive HPV self-collected sample who attend follow-up testing at 30, 60, or 90 days after mail out of the results. The CHOiCE trial will provide strong and important evidence allowing us to determine if and how HPV self-sampling can be used to increase participation in

Chemopreventive effects of Ku-jin tea against AOM-induced precancerous colorectal lesions in rats and metabolomic analysis.

PubMed

Bi, Wu; Liu, Haibo; Shen, Jie; Zhang, Ling-Hua; Li, Pei; Peng, Bing; Cao, Li; Zhang, Pengfei; He, Chunnian; Xiao, Peigen

2017-11-21

Ku-jin tea (KJT) is a health beverage prepared from the leaves of the plant Acer tataricum subsp. ginnala that has been consumed in some regions of China for thousands of years. KJT contains high levels of anti-inflammatory and antioxidative compounds such as ginnalins, but little is known about the chemopreventive effect of KJT on colon cancer. In this study, we investigated the preventive effects of KJT on colon carcinogenesis using the azoxymethane (AOM)-induced precancerous colorectal lesion model in rats. The results showed that the number of aberrant crypts, aberrant crypt foci (ACF) and crypts/focus in rats of the KJT + AOM group were significantly decreased compared with rats of the AOM group (p < 0.01). Further exploration of the prevention mechanism of KJT by UPLC-QTOF/MS-based urinary metabolomics showed that 5 metabolic pathways were modulated, including purine metabolism and amino acid metabolism, in the group with KJT. In addition, the levels of the immunomodulatory cytokines IL-1α and IL-10 were significantly decreased, and the levels of IL-2 in the serum of AOM rats increased after KJT treatment. Our present data suggest that KJT can inhibit AOM-induced colonic ACF formation and might be a useful chemopreventive agent against colorectal carcinogenesis.

Injury survey in Choi Kwang Do (CKD) martial art practitioners around the world: CKD is a safe form of training for adults.

PubMed

Jee, Yong-Seok; Eun, Denny

2018-02-01

Among the many sports and activities to choose from, martial arts are becoming increasingly popular for health and fitness. Due to the different nature of the various styles of martial arts, injuries are not uncommon. Though there have been studies on the injury rates of several martial art styles, there have been none regarding Choi Kwang Do (CKD), a noncompetitive martial art with relaxed and fluid movements designed to promote health and fitness for people of all ages. The purpose of this study was to examine the rate of injury for adults training in CKD to find out whether this is a safe style of martial art for adults. This study found the prevalence, causes, severity, and types of injuries from CKD practitioners around the world through an online survey targeting adults (n=122), aged 18 or older, with varying years of training experience. The annual rate of injury was 11.73 for every 100 CKD practitioners. There was no correlation between the length of training experience and injury. Training frequency and duration had no significant relationship with injury rates. A significant positive relationship between training intensity and injury existed ( P =0.009). The results of the study found that CKD can be an attractive option for adults of any age who are looking to learn a martial art or choose a physical activity with a low risk of injury, however the training intensity should be kept at a level that is not excessively high.

Injury survey in Choi Kwang Do (CKD) martial art practitioners around the world: CKD is a safe form of training for adults

PubMed Central

Jee, Yong-Seok; Eun, Denny

2018-01-01

Among the many sports and activities to choose from, martial arts are becoming increasingly popular for health and fitness. Due to the different nature of the various styles of martial arts, injuries are not uncommon. Though there have been studies on the injury rates of several martial art styles, there have been none regarding Choi Kwang Do (CKD), a noncompetitive martial art with relaxed and fluid movements designed to promote health and fitness for people of all ages. The purpose of this study was to examine the rate of injury for adults training in CKD to find out whether this is a safe style of martial art for adults. This study found the prevalence, causes, severity, and types of injuries from CKD practitioners around the world through an online survey targeting adults (n=122), aged 18 or older, with varying years of training experience. The annual rate of injury was 11.73 for every 100 CKD practitioners. There was no correlation between the length of training experience and injury. Training frequency and duration had no significant relationship with injury rates. A significant positive relationship between training intensity and injury existed (P=0.009). The results of the study found that CKD can be an attractive option for adults of any age who are looking to learn a martial art or choose a physical activity with a low risk of injury, however the training intensity should be kept at a level that is not excessively high. PMID:29511654

EEG-Based Brain-Computer Interface for Decoding Motor Imagery Tasks within the Same Hand Using Choi-Williams Time-Frequency Distribution

PubMed Central

Alwanni, Hisham; Baslan, Yara; Alnuman, Nasim; Daoud, Mohammad I.

2017-01-01

This paper presents an EEG-based brain-computer interface system for classifying eleven motor imagery (MI) tasks within the same hand. The proposed system utilizes the Choi-Williams time-frequency distribution (CWD) to construct a time-frequency representation (TFR) of the EEG signals. The constructed TFR is used to extract five categories of time-frequency features (TFFs). The TFFs are processed using a hierarchical classification model to identify the MI task encapsulated within the EEG signals. To evaluate the performance of the proposed approach, EEG data were recorded for eighteen intact subjects and four amputated subjects while imagining to perform each of the eleven hand MI tasks. Two performance evaluation analyses, namely channel- and TFF-based analyses, are conducted to identify the best subset of EEG channels and the TFFs category, respectively, that enable the highest classification accuracy between the MI tasks. In each evaluation analysis, the hierarchical classification model is trained using two training procedures, namely subject-dependent and subject-independent procedures. These two training procedures quantify the capability of the proposed approach to capture both intra- and inter-personal variations in the EEG signals for different MI tasks within the same hand. The results demonstrate the efficacy of the approach for classifying the MI tasks within the same hand. In particular, the classification accuracies obtained for the intact and amputated subjects are as high as 88.8% and 90.2%, respectively, for the subject-dependent training procedure, and 80.8% and 87.8%, respectively, for the subject-independent training procedure. These results suggest the feasibility of applying the proposed approach to control dexterous prosthetic hands, which can be of great benefit for individuals suffering from hand amputations. PMID:28832513

Metabolic Flux Redirection and Transcriptomic Reprogramming in the Albino Tea Cultivar ‘Yu-Jin-Xiang’ with an Emphasis on Catechin Production

PubMed Central

Liu, Guo-Feng; Han, Zhuo-Xiao; Feng, Lin; Gao, Li-Ping; Gao, Ming-Jun; Gruber, Margaret Y.; Zhang, Zhao-Liang; Xia, Tao; Wan, Xiao-Chun; Wei, Shu

2017-01-01

In this study, shade-induced conversion from a young pale/yellow leaf phenotype to a green leaf phenotype was studied using metabolic and transcriptomic profiling and the albino cultivar ‘Yu-Jin-Xiang’ (‘YJX’) of Camellia sinensis for a better understanding of mechanisms underlying the phenotype shift and the altered catechin and theanine production. Shaded leaf greening resulted from an increase in leaf chlorophyll and carotenoid abundance and chloroplast development. A total of 1,196 differentially expressed genes (DEGs) were identified between the ‘YJX’ pale and shaded green leaves, and these DEGs affected ‘chloroplast organization’ and ‘response to high light’ besides many other biological processes and pathways. Metabolic flux redirection and transcriptomic reprogramming were found in flavonoid and carotenoid pathways of the ‘YJX’ pale leaves and shaded green leaves to different extents compared to the green cultivar ‘Shu-Cha-Zao’. Enhanced production of the antioxidant quercetin rather than catechin biosynthesis was correlated positively with the enhanced transcription of FLAVONOL SYNTHASE and FLAVANONE/FLAVONOL HYDROXYLASES leading to quercetin accumulation and negatively correlated to suppressed LEUCOANTHOCYANIDIN REDUCTASE, ANTHOCYANIDIN REDUCTASE and SYNTHASE leading to catechin biosynthesis. The altered levels of quercetin and catechins in ‘YJX’ will impact on its tea flavor and health benefits. PMID:28332598

Metabolomic analysis of anti-hypoxia and anti-anxiety effects of Fu Fang Jin Jing Oral Liquid.

PubMed

Liu, Xia; Zhu, Wei; Guan, Shuhong; Feng, Ruihong; Zhang, Hui; Liu, Qiuhong; Sun, Peng; Lin, Donghai; Zhang, Naixia; Shen, Jun

2013-01-01

Herba Rhodiolae is a traditional Chinese medicine used by the Tibetan people for treating hypoxia related diseases such as anxiety. Based on the previous work, we developed and patented an anti-anxiety herbal formula Fu Fang Jin Jing Oral Liquid (FJJOL) with Herba Rhodiolae as a chief ingredient. In this study, the anti-hypoxia and anti-anxiety effects of FJJOL in a high altitude forced-swimming mouse model with anxiety symptoms will be elucidated by NMR-based metabolomics. In our experiments, the mice were divided randomly into four groups as flatland group, high altitude saline-treated group, high altitude FJJOL-treated group, and high altitude diazepam-treated group. To cause anxiety effects and hypoxic defects, a combination use of oxygen level decreasing (hypobaric cabin) and oxygen consumption increasing (exhaustive swimming) were applied to mice. After a three-day experimental handling, aqueous metabolites of mouse brain tissues were extracted and then subjected to NMR analysis. The therapeutic effects of FJJOL on the hypobaric hypoxia mice with anxiety symptoms were verified. Upon hypoxic exposure, both energy metabolism defects and disorders of functional metabolites in brain tissues of mice were observed. PCA, PLS-DA and OPLS-DA scatter plots revealed a clear group clustering for metabolic profiles in the hypoxia versus normoxia samples. After a three-day treatment with FJJOL, significant rescue effects on energy metabolism were detected, and levels of ATP, fumarate, malate and lactate in brain tissues of hypoxic mice recovered. Meanwhile, FJJOL also up-regulated the neurotransmitter GABA, and the improvement of anxiety symptoms was highly related to this effect. FJJOL ameliorated hypobaric hypoxia effects by regulating energy metabolism, choline metabolism, and improving the symptoms of anxiety. The anti-anxiety therapeutic effects of FJJOL were comparable to the conventional anti-anxiety drug diazepam on the hypobaric hypoxia mice. FJJOL might serve as

Autonomous Non-Linear Classification of LPI Radar Signal Modulations

DTIC Science & Technology

2007-09-01

Wigner - Ville distribution ( WVD ), the Choi-Williams distribution (CWD) and a Quadrature...accomplished using the images from the Wigner - Ville distribution and the Choi-Williams distribution for polyphase modulations. For the WVD images, radon...this work. Four detection techniques including the Wigner - Ville distribution ( WVD ), the Choi-Williams distribution (CWD), Quadrature Mirror

United States Forces Korea > Home

Science.gov Websites

commander; Gen. Leem Ho Young, Combined Forces Command deputy commander; and Gen. Lee Sun-jin, Gen. Lee, Sun Forces Command deputy commander; and Gen. Lee Sun-jin, Gen. Lee, Sun-Jin, Chairman of the Republic of deputy commander; and Gen. Lee Sun-jin, Gen. Lee, Sun-Jin, Chairman of the Republic of Korea Joint Chiefs

Metabolomic Analysis of Anti-Hypoxia and Anti-anxiety Effects of Fu Fang Jin Jing Oral Liquid

PubMed Central

Guan, Shuhong; Feng, Ruihong; Zhang, Hui; Liu, Qiuhong; Sun, Peng; Lin, Donghai; Zhang, Naixia; Shen, Jun

2013-01-01

Background Herba Rhodiolae is a traditional Chinese medicine used by the Tibetan people for treating hypoxia related diseases such as anxiety. Based on the previous work, we developed and patented an anti-anxiety herbal formula Fu Fang Jin Jing Oral Liquid (FJJOL) with Herba Rhodiolae as a chief ingredient. In this study, the anti-hypoxia and anti-anxiety effects of FJJOL in a high altitude forced-swimming mouse model with anxiety symptoms will be elucidated by NMR-based metabolomics. Methods In our experiments, the mice were divided randomly into four groups as flatland group, high altitude saline-treated group, high altitude FJJOL-treated group, and high altitude diazepam-treated group. To cause anxiety effects and hypoxic defects, a combination use of oxygen level decreasing (hypobaric cabin) and oxygen consumption increasing (exhaustive swimming) were applied to mice. After a three-day experimental handling, aqueous metabolites of mouse brain tissues were extracted and then subjected to NMR analysis. The therapeutic effects of FJJOL on the hypobaric hypoxia mice with anxiety symptoms were verified. Results Upon hypoxic exposure, both energy metabolism defects and disorders of functional metabolites in brain tissues of mice were observed. PCA, PLS-DA and OPLS-DA scatter plots revealed a clear group clustering for metabolic profiles in the hypoxia versus normoxia samples. After a three-day treatment with FJJOL, significant rescue effects on energy metabolism were detected, and levels of ATP, fumarate, malate and lactate in brain tissues of hypoxic mice recovered. Meanwhile, FJJOL also up-regulated the neurotransmitter GABA, and the improvement of anxiety symptoms was highly related to this effect. Conclusions FJJOL ameliorated hypobaric hypoxia effects by regulating energy metabolism, choline metabolism, and improving the symptoms of anxiety. The anti-anxiety therapeutic effects of FJJOL were comparable to the conventional anti-anxiety drug diazepam on the

[Missionary Medicine of Canadian Presbytery and Korean Doctors under Japanese Occupation--focusing Sung-jin and Ham-heung].

PubMed

Heo, Yun-Jung; Cho, Young-Soo

2015-12-01

In East Asia during the second half of the 19th century, overseas mission work by Protestant churches thrived. Missionaries built schools and hospitals and effectively used them for evangelism. In the 20th century when Social Gospel Movement was expanding, medical work has been recognized as a significant mission service in and by itself. This article reviewed the construction and characteristics of missions work conducted by Canadian Presbytery; missionary doctors and Korean doctors who worked at the mission hospitals; why the missionary medical work had to stop; and career paths taken by Korean doctors upon liberation from Japanese occupation. The Canadian Presbytery missionaries, unlike other denomination missionaries, were rather critical of Imperial Japan, but supportive towards Koreans. This could have stemmed from the reflection of their own experience of once a colony of British Empire and also their value system that promotes egalitarian, democratic and progressive theology. The Sung-jin and Ham-heung Mission Bases were a community, interacting organically as a 'Triangle of Church, School and Hospital.' The missionaries mobilized the graduates from Christian schools and organized a Young Men's Christian Association (YMCA). Some of the graduates were trained to become medical doctors or assistants and worked at mission hospitals. Missionary doctors' approaches to balancing evangelism and medical practice varied. For example, Robert Grieson went through confusion and struggled to balance conflicting roles as a pastor for evangelism and also as a physician. Kate McMillan, on the other hand, had less burden for evangelism than Grieson, and focused on medical work by taking advantage of the opportunity that, as a woman, she can easily approach Korean women. Still another case was Florence Murray who practised evangelism within the hospital setting, and successfully carried out the role as a hospital administrator, going beyond 'women's work' as McMillan did

Study on Inhibitory Effect of MaiMenDong Decoction and WeiJing Decoction Combination with Cisplatin on NCI-A549 Xenograft in Nude Mice and Its Mechanism.

PubMed

Xiong, Fei; Jiang, Miao; Chen, Meijuan; Wang, Xiaoxia; Zhang, Shiping; Zhou, Jing; Li, Ke; Sheng, Yan; Yin, Lian; Tang, Yuping; Ye, Lihong; Wu, Mianhua; Fu, Haian; Zhang, Xu

2017-01-01

MaiMenDong Decoction and WeiJing Decoction (Jin formula) is a traditional Chinese medication that consists of 8 medicinal plants, which recorded in the classical TCM literature Jin Kui Yao Lue and has been utilized in the treatment of lung diseases for hundreds of years in China. The present study aimed to determine the anti-tumor activity and the underlying mechanisms of Jin formula combined with cisplatin in the treatment of non-small cell lung cancer (NSCLC). Xenograft model of NCI-A549 was established in Balb/c nude mice. Five groups, including normal, MOCK, Jin, cisplatin (DDP), and Jin+DDP were included in the study. We found that Jin formula ameliorated the body weight loss caused by DDP 15 days after drug administration. Moreover, the combination of Jin with DDP enhanced the anti-tumor function of DDP. Microarray analysis showed that Jin suppressed gene expression of certain pathways which regulating cell cycle and apoptosis. Furthermore, DDP mainly decreased the gene expression level of angiogenesis associated factors, such as VEGFA, TGF-β and MMP-1. Moreover, co-treatment with Jin and DDP not only down-regulated Bcl-2 and E2F1, but also decreased the expression of MYC, MET, and MCAM. In addition, co-formula decreased the levels of p-AKT (thr308) and p-PTEN, increased Bax/Bcl-2 value, and resulted in apoptosis of tumor cells. Taken together , Jin+DDP significantly inhibited the growth of A549 cell transplanted solid tumor with slight side effect compared to the treatment by DDP only, and had a better effect than the Jin group. The mechanisms may be mainly associated with inactivation of PI3K/AKT pathway and apoptosis induction.

Delivery of Nano-Tethered Therapies to Brain Metastases of Primary Breast Cancer Using a Cellular Trojan Horse

DTIC Science & Technology

2014-10-01

REFERENCES: 1. M.-R. Choi et al., Delivery of nanoparticles to brain metastases of breast cancer using a cellular Trojan horse. Cancer Nanotechnol. 3...subtype”, Ann Oncol, 2010, 21: 942– 948. [2] Mi-Ran Choi, et al., “Delivery of nanoparticles to brain metastases of breast cancer using a cellular Trojan...horse”, Cancer Nano, 2012; 3: 47- 54. [3] Mi-Ran Choi, et al., “A cellular Trojan Horse for delivery of therapeutic nanoparticles into tumors

Effect of plant species on nitrogen recovery in aquaponics.

PubMed

Hu, Zhen; Lee, Jae Woo; Chandran, Kartik; Kim, Sungpyo; Brotto, Ariane Coelho; Khanal, Samir Kumar

2015-01-01

Nitrogen transformations in aquaponics with different edible plant species, i.e., tomato (Lycopersicon esculentum) and pak choi (Brassica campestris L. subsp. chinensis) were systematically examined and compared. Results showed that nitrogen utilization efficiencies (NUE) of tomato- and pak choi-based aquaponic systems were 41.3% and 34.4%, respectively. The abundance of nitrifying bacteria in tomato-based aquaponics was 4.2-folds higher than that in pak choi-based aquaponics, primarily due to its higher root surface area. In addition, tomato-based aquaponics had better water quality than that of pak choi-based aquaponics. About 1.5-1.9% of nitrogen input were emitted to atmosphere as nitrous oxide (N2O) in tomato- and pak choi-based aquaponic systems, respectively, suggesting that aquaponics is a potential anthropogenic source of N2O emission. Overall, this is the first intensive study that examined the role plant species played in aquaponics, which could provide new strategy in designing and operating an aquaponic system. Copyright © 2015 Elsevier Ltd. All rights reserved.

Impact of a Telehealth Program With Voice Recognition Technology in Patients With Chronic Heart Failure: Feasibility Study.

PubMed

Lee, Heesun; Park, Jun-Bean; Choi, Sae Won; Yoon, Yeonyee E; Park, Hyo Eun; Lee, Sang Eun; Lee, Seung-Pyo; Kim, Hyung-Kwan; Cho, Hyun-Jai; Choi, Su-Yeon; Lee, Hae-Young; Choi, Jonghyuk; Lee, Young-Joon; Kim, Yong-Jin; Cho, Goo-Yeong; Choi, Jinwook; Sohn, Dae-Won

2017-10-02

population, there was no significant interval change in laboratory and functional outcome variables after 12 weeks of ICT-based telehealth program. In patients with good adherence to ICT-based telehealth program, there was a significant improvement in the mean uNa (103.1 to 78.1; P=.01) but not in those without (85.4 to 96.9; P=.49). Similarly, a marginal improvement in MLHFQ scores was only observed in patients with good adherence (27.5 to 21.4; P=.08) but not in their counterparts (19.0 to 19.7; P=.73). The mean 6-min walk distance and NT-proBNP were not significantly increased in patients regardless of their adherence. Short-term application of ICT-based telehealth program with voice recognition technology showed the potential to improve uNa values and MLHFQ scores in HF patients, suggesting that better control of sodium intake and greater quality of life can be achieved by this program. ©Heesun Lee, Jun-Bean Park, Sae Won Choi, Yeonyee E Yoon, Hyo Eun Park, Sang Eun Lee, Seung-Pyo Lee, Hyung-Kwan Kim, Hyun-Jai Cho, Su-Yeon Choi, Hae-Young Lee, Jonghyuk Choi, Young-Joon Lee, Yong-Jin Kim, Goo-Yeong Cho, Jinwook Choi, Dae-Won Sohn. Originally published in JMIR Mhealth and Uhealth (http://mhealth.jmir.org), 02.10.2017.

Structure analysis and core community detection of embodied resources networks among regional industries

NASA Astrophysics Data System (ADS)

He, Xijun; Dong, Yanbo; Wu, Yuying; Wei, Guodan; Xing, Lizhi; Yan, Jia

2017-08-01

To address the double pressure of scarce resources and regional industrial isomorphism, this paper applied the concepts of exergy and embodied resources based on economic input-output (I-O) data. We constructed the embodied resources networks among the regional industries of Beijing-Tianjin-Hebei (also known as Jing-Jin-Ji) in China. We analyzed the rules of embodied resources consumption in the area's industries, identified the core community structures, and studied the characteristics of industrial homogeneity through regional comparisons. The results showed that the dependence on scarce resources of industrial operations in Beijing was less than in Jin-Ji, while the dependence on finance, technology, information, and other service resources in Beijing was higher than in Jin-Ji. The I-O efficiency of embodied resources among industries and the agglomeration of correlation relationships in industries with large embodied resources were higher than in Jin-Ji. The industrial coincidence degree in the ;bridge; industries and in the core community in Jin-Ji was higher than in Jing-Jin and Jing-Ji, which means the industrial homogeneous competition of Jin-Ji was higher, too. This study makes a significant contribution toward promoting the dislocation development of regional industries, accelerating the coordination of resources, and reducing homogeneity competition.

Internationalization of China's Shanxi Province New Merchants: Implications and Use in Teaching IB

ERIC Educational Resources Information Center

Guo, Juanjuan

2017-01-01

The Jin (Jin refers to Shanxi Province) merchants have a very important position in the history of Chinese business. The Jin merchants is a business course that investigates Shanxi businessmen and their business activities. As a local characteristic of the business curriculum of China, this course is taught in a number of universities. Taking the…

Microring Resonators Vertically Coupled to Buried Heterostructure Bus Waveguides

DTIC Science & Technology

2005-06-01

Seung June Choi, Kostadin Djordjev, Sang Jun Choi, P. Daniel Dapkus, Fellow, IEEE, Wilson Lin, Giora Griffel , Ray Menna, and John Connolly Abstract—The...Department of Electrical Engineering-Electrophysics, University of Southern California, Los Angeles, CA 90089 USA. W. Lin, G. Griffel , R. Menna, and J

Cognitive Contours: Recent Work on Cross-Cultural Psychology and Its Relevance for Education

ERIC Educational Resources Information Center

Davies, W. Martin

2007-01-01

This paper outlines new work in cross-cultural psychology largely drawn from Nisbett, Choi, and Smith ("Cognition," 65, 15-32, 1997); Nisbett, Peng, Choi, & Norenzayan, "Psychological Review," 108(2), 291-310, 2001; Nisbett, "The Geography of Thought: How Asians and Westerners Think Differently...and Why." New…

Thermal to Visible Face Recognition

DTIC Science & Technology

2012-04-01

Thermal to Visible Face Recognition Jonghyun Choi†, Shuowen Hu‡, S. Susan Young‡ and Larry S. Davis† †University of Maryland, College Park, MD ‡U.S...Bourlai et al.7 Further author information: (Send correspondence to Jonghyun Choi) Jonghyun Choi: E-mail: jhchoi@umd.edu, Telephone: 1 301 335 3866 This

Assessment of Muscle Fatigue from TF Distributions of SEMG Signals

DTIC Science & Technology

2008-06-01

Wigner - Ville distribution ( WVD ) holds the...techniques used to build a TF distribution of SEMG signals, namely spectrogram, Wigner - Ville , Choi- Williams and smoothed pseudo Wigner - Ville . SEMG signals...spectrogram but also other Cohen’s class TF distributions , such as the Choi-Williams distribution (CWD) and the smoothed pseudo Wigner - Ville distribution

Preparation of Solvent-Dispersible Graphene and its Application to Nanocomposites

DTIC Science & Technology

2016-06-14

2011, 115, 5422-5428. 31. E.-Y. Choi, W. S. Choi, Y. B. Lee and Y. –Y. Noh, Nanotechnology , 2011, 22, 365601. DISTRIBUTION A. Approved for public...2009, 13, 1667-1669. 44. D. Li, M. B. Müller, S. Gilje, R. B. Kaner and G. G. Wallace, Nature Nanotechnology , 2008, 3, 101-105. 45. J. Gassan and

Nonlinear Polarization Conversion using Microring Resonators

DTIC Science & Technology

2007-06-08

Office MURI grant W911NF-04-01-0203. References 1. B. E. Little and S. T. Chu, Opt. Photon. News 11(11), 24 (2000). 2. G. Griffel , IEEE Photon. Technol...Thompson Learning, 1976). 15. S. J. Choi, K. Djordjev, S. J. Choi, P. D. Dapkus, W. Lin, G. Griffel , R. Menna, and J. Connoly, IEEE Photon. Technol. Lett

Intercultural Adaptation and Validity Study: Universal Science Literacy Scale (USLS)

ERIC Educational Resources Information Center

Çelik, Cüneyd; Can, Sendil

2017-01-01

The purpose of the current study is to adapt "The Universal Science Literacy Scale" developed by Mun, Shin, Lee, Kim, Choi, Choi and Krajcik into Turkish. The study group of the current research is comprised of a total of 645 pre-service science teachers from 6 different universities of Turkey. In the first stage of the adaptation study,…

Joint Institute for Nanoscience Annual Report 2004

DOE Office of Scientific and Technical Information (OSTI.GOV)

Baer, Donald R.; Campbell, Charles

Due to the inherently interdisciplinary nature of nanoscience and nanotechnology, research in this arena is often significantly enhanced through creative cooperative activities. The Joint Institute for Nanoscience (JIN) is a venture of the University of Washington (UW) and Pacific Northwest National Laboratory (PNNL) to encourage and enhance high impact and high quality nanoscience and nanotechnology research that leverages the strengths and capabilities of both institutions, and to facilitate education in these areas. This report summarizes JIN award activities that took place during fiscal year 2004 and provides a historical list of JIN awardees, their resulting publications, and JIN-related meetings. Majormore » portions of the JIN efforts and resources are dedicated to funding graduate students and postdoctoral research associates to perform research in collaborations jointly directed by PNNL staff scientists and UW professors. JIN fellowships are awarded on the basis of applications that include research proposals. They have been very successful in expanding collaborations between PNNL and UW, which have led to many excellent joint publications and presentations and enhanced the competitiveness of both institutions for external grant funding. JIN-based interactions are playing a significant role in creating new research directions and reshaping existing research programs at both the UW and PNNL. The JIN also co-sponsors workshops on Nanoscale Science and Technology, four of which have been held in Seattle and one in Richland. In addition to involving PNNL staff in various UW nanoscience courses and seminars, a National Science Foundation grant, Development of UW-PNL Collaborative Curriculums in Nano-Science and Technology, has allowed the development of three intensive short courses that are taught by UW faculty, PNNL staff, and faculty from other institutions, including Washington State University, the University of Idaho, Stanford University, and the

Kevlar Vest Protection against Blast Overpressure Brain Injury: Systemic Contributions to Injury Etiology

DTIC Science & Technology

2015-07-01

F. S., Invest. Ophthal- mol. Vis. Sci. 2003, 44, 3219–3225. [52] Sun , Y., Jin , K., Xie, L., Childs, J., Mao, X. O., Logvinova, A., Greenberg, D. A...traumatic stress disorder (PTSD) within the Department of Defense. Clin. Neuropsychol. 23, 1291–1298. Jin , K., Zhu, Y., Sun , Y., Mao, X. O., Xie, L., and...task-specific neurobehavioral experience. Neurosci. Lett. 431, 226–230. Jin , K., Zhu, Y., Sun , Y., Mao, X. O., Xie, L., and Greenberg, D. A. (2002

JPRS Report, China, Maos Legacy in Anhui, Rural Reform 1978-80.

DTIC Science & Technology

1989-07-28

boil some noodles , and then asked Zhan Shaozhou: "What brought you here?" "To report to you!" "Report what?" "It has begun. More is being done...policy of looking after serious disaster areas on holidays, providing each person with 3 jin of rice, 2 jin of noodles , and xh jin of meat. They went...abandon for an instant ! Chapter 6. A Tragedy Not To Be Repeated—1980: The Great Anhui Flood History Continues To Testify 1 The Earth, which nurtures us

Preemptive Approach to Improving Survival in Epithelial Ovarian Cancer

DTIC Science & Technology

2012-06-01

Metab 2008;93:3471–7. 692[87] Cho JH, Lee JG, Yang YI, Kim JH, Ahn JH, Baek NI, Lee KT, Choi JH. Eupatilin, a die- 693tary flavonoid , induces G2/M cell...Metab 2008;93:3471–7. 692[87] Cho JH, Lee JG, Yang YI, Kim JH, Ahn JH, Baek NI, Lee KT, Choi JH. Eupatilin, a die- 693tary flavonoid , induces G2/M

76 FR 56397 - Small Diameter Graphite Electrodes from the People's Republic of China: Final Results of the...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-13

... value (``SV'') information: SGL Carbon LLC and Superior Graphite Co. (``Petitioners''); Fushun Jinly Petrochemical Carbon Co., Ltd. (``Fushun Jinly''); and Beijing Fangda Carbon Tech Co., Ltd. (``Beijing Fangda''), Chengdu Rongguang Carbon Co., Ltd. (``Rongguang''), Fangda Carbon New Material Co., Ltd. (``Fangda Carbon...

JILA BEC/Ultracold Atoms Homepage

Science.gov Websites

JILA BEC & Ultracold Atoms Bose Einstein Condensate Eric Cornell Cornell Group Debbie Jin Jin Group Jun Ye Ye Group Dana Anderson Anderson Group What is BEC? Easy BEC Machine Nobel BEC BibTek Papers

Identification of Licopyranocoumarin and Glycyrurol from Herbal Medicines as Neuroprotective Compounds for Parkinson's Disease

PubMed Central

Fujimaki, Takahiro; Saiki, Shinji; Tashiro, Etsu; Yamada, Daisuke; Kitagawa, Mitsuhiro; Hattori, Nobutaka; Imoto, Masaya

2014-01-01

In the course of screening for the anti-Parkinsonian drugs from a library of traditional herbal medicines, we found that the extracts of choi-joki-to and daio-kanzo-to protected cells from MPP+-induced cell death. Because choi-joki-to and daio-kanzo-to commonly contain the genus Glycyrrhiza, we isolated licopyranocoumarin (LPC) and glycyrurol (GCR) as potent neuroprotective principals from Glycyrrhiza. LPC and GCR markedly blocked MPP+-induced neuronal PC12D cell death and disappearance of mitochondrial membrane potential, which were mediated by JNK. LPC and GCR inhibited MPP+-induced JNK activation through the suppression of reactive oxygen species (ROS) generation, thereby inhibiting MPP+-induced neuronal PC12D cell death. These results indicated that LPC and GCR derived from choi-joki-to and daio-kanzo-to would be promising drug leads for PD treatment in the future. PMID:24960051

South Korea’s Commercial Liberal Approach to Security

DTIC Science & Technology

2002-03-01

Won -Keun Choi . “New Challenges Of The Korean Economy.” The Journal of East Asian Affairs. Vol.XIV, No.2, Fall/Winter 2000,pp...of Defense Analysis, Vol. VIII, No.2, Winter 1996, pp 223-268. Ko, Jong-Moon, Yung-Il So, Won -Keun Choi . “New Challenges Of The... Seung , Ho Joo and Tae Hwan Kwak, eds. Huntington: Nova Science Publishers, Inc, 2001, pp 185. 5 made by the South Korean

77 FR 40854 - Small Diameter Graphite Electrodes From the People's Republic of China: Final Results of the...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-11

...). The administrative review covers Fushun Jinly Petrochemical Carbon Co., Ltd. (Fushun Jinly), Xinghe County Muzi Carbon Co., Ltd. (Muzi Carbon), Sichuan Guanghan Shida Carbon Co., Ltd. (Shida Carbon), Jilin Carbon Import and Export Company (Jilin Carbon), the Fangda Group (comprised of five collapsed companies...

77 FR 15042 - Small Diameter Graphite Electrodes From the People's Republic of China: Amended Final Results of...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-14

..., Department of Commerce. DATES: Effective Date: March 14, 2012. SUMMARY: On September 13, 2011, the Department... Jinly Petrochemical Carbon Co., Ltd. (``Fushun Jinly''); Beijing Fangda Carbon Tech Co., Ltd. (``Beijing Fangda''), Fangda Carbon New Material Co., Ltd. (``Fangda Carbon''), Fushun Carbon Co., Ltd. (```Fushun...

[Philological structure of Dan xi shou jing (Danxi's Hand Mirror)].

PubMed

Chen, Yincan; Zhu, Jianping

2015-05-01

Zhu Danxi, one of the four Major Schools of the Jin-Yuan Dynasties, had a lot of works circulated with its authorship in disarray. Part of the works were compiled by his disciples, while others were by his self-taught followers based on prior circulated Danxi's originals, plus some apocryphal so-called Danxi's works circulated posthumously. When sorting out Danxi's Hand Mirror, we found that some of its contents are closely related to Bei ji qian jin yao fang (Essential Prescriptions Worth a Thousand Gold for Emergencies), Qian jin yi fang (Supplements to Qian jin yao fang), Tai ping sheng hui fang (Peaceful Holy Benevolent Prescriptions), Zhu jie shang han lun (Annotated Treatises of Cold Pathogenic Disease), Shang han ming li lun (Elucidation of Cold Pathogenic Disease), Ge zhi yu lun (Treatise of Inquiring the Properties of Things), either by transcription or with an identical origin. By clearing their relationships, it can provide assistance to the research of the philological structure of Danxi's hand Mirror.

Prognosis of Electrical Faults in Permanent Magnet AC Machines using the Hidden Markov Model

DTIC Science & Technology

2010-11-10

time resolution and high frequency resolution Tiling is variable Wigner Ville Distribution Defined as W (t, ω) = ∫ s(t + τ 2 )s∗(t − τ 2 )e−jωτdτ...smoothed version of the Wigner distribution Amount of smoothing is controlled by σ Smoothing comes with a tradeoff of reduced resolution UNCLAS: Dist A...the Wigner or Choi-Williams distributions Although for Wigner and Choi-Williams distributions the probabilities are close for the early fault

The U.S. Ground Combat Presence in Korea: In Defense of U.S. Interests or a Strategic Dinosaur

DTIC Science & Technology

1983-05-09

Whatever the reasons, the assassination set off a year of political turbulence in South Korea. Choi Kyu Hah became the acting president and promised to...Korean Army, a December 1979 coup resulted in the Army Chief of Staff - General Chung Seung Hwa - being replaced. A number of other senior officers in the...parlimentary elections promised by Choi . This brought him into conflict with Kim Young Sam, leader of the opposition New Democratic Party (NDP), and the

Meso-size Effect from Self-assembled Carbon Structures and Their Device Applications

DTIC Science & Technology

2013-08-23

electrical photoresponse from pentacene 1D disks and 2D wires, and 3) dramatic increase of solubility in water of zinc phthalocyanine (ZnPc) nanowires...Hong, M.; Son, M.; Choi, H. C.* “Crystal Plane-Dependent Photoluminescence Activity of Pentacene 1D Wire and 2D Disk Crystals.” Angew. Chem. Int...Ed. 2013, 52, 5997-6001. [7] Park, J. E.; Hong, M.; Son, M.; Choi, H. C.* “Crystal Plane-Dependent Photoluminescence Activity of Pentacene 1D Wire

Comparison of performance of various tumour response criteria in assessment of regorafenib activity in advanced gastrointestinal stromal tumours after failure of imatinib and sunitinib.

PubMed

Shinagare, Atul B; Jagannathan, Jyothi P; Kurra, Vikram; Urban, Trinity; Manola, Judith; Choy, Edwin; Demetri, George D; George, Suzanne; Ramaiya, Nikhil H

2014-03-01

To compare performance of various tumour response criteria (TRCs) in assessment of regorafenib activity in patients with advanced gastrointestinal stromal tumour (GIST) with prior failure of imatinib and sunitinib. Twenty participants in a phase II trial received oral regorafenib (median duration 47 weeks; interquartile range (IQR) 24-88) with computed tomography (CT) imaging at baseline and every two months thereafter. Tumour response was prospectively determined on using Response Evaluation Criteria in Solid Tumours (RECIST) 1.1, and retrospectively reassessed for comparison per RECIST 1.0, World Health Organization (WHO) and Choi criteria, using the same target lesions. Clinical benefit rate [CBR; complete or partial response (CR or PR) or stable disease (SD)≥16 weeks] and progression-free survival (PFS) were compared between various TRCs using kappa statistics. Performance of TRCs in predicting overall survival (OS) was compared by comparing OS in groups with progression-free intervals less than or greater than 20 weeks by each TRC using c-statistics. PR was more frequent by Choi (90%) than RECIST 1.1, RECIST 1.0 and WHO (20% each), however, CBR was similar between various TRCs (overall CBR 85-90%, 95-100% agreement between all TRC pairs). PFS per RECIST 1.0 was similar to RECIST 1.1 (median 44 weeks versus 58 weeks), and shorter for WHO (median 34 weeks) and Choi (median 24 weeks). With RECIST 1.1, RECIST 1.0 and WHO, there was moderate concordance between PFS and OS (c-statistics 0.596-0.679). Choi criteria had less favourable concordance (c-statistic 0.506). RECIST 1.1 and WHO performed somewhat better than Choi criteria as TRC for response evaluation in patients with advanced GIST after prior failure on imatinib and sunitinib. Copyright © 2013 Elsevier Ltd. All rights reserved.

77 FR 13284 - Small Diameter Graphite Electrodes From the People's Republic of China: Preliminary Results and...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-06

... with 19 CFR 351.213(b) from Fushun Jinly Petrochemical Carbon Co., Ltd. (Fushun Jinly), Xinghe County Muzi Carbon Co., Ltd. (Muzi Carbon), Sichuan Guanghan Shida Carbon Co., Ltd. (Shida Carbon), and Beijing Fangda Carbon Tech Co., Ltd., Chengdu Rongguang Carbon Co., Ltd., Fangda Carbon New Material Co...

Pneumothorax size measurements on digital chest radiographs: Intra- and inter- rater reliability.

PubMed

Thelle, Andreas; Gjerdevik, Miriam; Grydeland, Thomas; Skorge, Trude D; Wentzel-Larsen, Tore; Bakke, Per S

2015-10-01

Detailed and reliable methods may be important for discussions on the importance of pneumothorax size in clinical decision-making. Rhea's method is widely used to estimate pneumothorax size in percent based on chest X-rays (CXRs) from three measure points. Choi's addendum is used for anterioposterior projections. The aim of this study was to examine the intrarater and interrater reliability of the Rhea and Choi method using digital CXR in the ward based PACS monitors. Three physicians examined a retrospective series of 80 digital CXRs showing pneumothorax, using Rhea and Choi's method, then repeated in a random order two weeks later. We used the analysis of variance technique by Eliasziw et al. to assess the intrarater and interrater reliability in altogether 480 estimations of pneumothorax size. Estimated pneumothorax sizes ranged between 5% and 100%. The intrarater reliability coefficient was 0.98 (95% one-sided lower-limit confidence interval C 0.96), and the interrater reliability coefficient was 0.95 (95% one-sided lower-limit confidence interval 0.93). This study has shown that the Rhea and Choi method for calculating pneumothorax size has high intrarater and interrater reliability. These results are valid across gender, side of pneumothorax and whether the patient is diagnosed with primary or secondary pneumothorax. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

Further summation formulae related to generalized harmonic numbers

NASA Astrophysics Data System (ADS)

Zheng, De-Yin

2007-11-01

By employing the univariate series expansion of classical hypergeometric series formulae, Shen [L.-C. Shen, Remarks on some integrals and series involving the Stirling numbers and [zeta](n), Trans. Amer. Math. Soc. 347 (1995) 1391-1399] and Choi and Srivastava [J. Choi, H.M. Srivastava, Certain classes of infinite series, Monatsh. Math. 127 (1999) 15-25; J. Choi, H.M. Srivastava, Explicit evaluation of Euler and related sums, Ramanujan J. 10 (2005) 51-70] investigated the evaluation of infinite series related to generalized harmonic numbers. More summation formulae have systematically been derived by Chu [W. Chu, Hypergeometric series and the Riemann Zeta function, Acta Arith. 82 (1997) 103-118], who developed fully this approach to the multivariate case. The present paper will explore the hypergeometric series method further and establish numerous summation formulae expressing infinite series related to generalized harmonic numbers in terms of the Riemann Zeta function [zeta](m) with m=5,6,7, including several known ones as examples.

Northeast Asia Regional Security and the United States Military: Context, Presence, and Roles

DTIC Science & Technology

2002-11-01

27 Doug Struck, “North Korean Growth Reported,” The Washington Pos,. September 5, 2000. 28 Hae Won Choi ; “Korean Plans for Northern Détente Dented...Pressed to Halt Kumgang Tours,” The Korea Herald, March 7, 2001. 30 Hae Won Choi . Op cit. 31 Harrison, “Time to Leave Korea?” 71. 32 John Pomfret...and then went on to serve as an Assistant Professor in the Department of Social Sciences at West Point. In 2001, Major Bryant won a Council on

Preparation for a Clinical Trial Using Adoptive Transfer of Tumor-Reactive TGF_Beta-Insensitive CD8+ T Cells for Treatment of Prostate Cancer

DTIC Science & Technology

2006-07-01

Park,1 Robert E. Meyer,2 Shilajit Kundu,1 Michael Pins,2 Borko Javonovic,3 Timothy Kuzel,4 Seong-Jin Kim,5 Luk Van Parijs,6 Norm Smith,1 Larry Wong,1...cycle Qiang Zhang,1 Ximing Yang,2,5 Shilajit D. Kundu,1 Michael Pins,2,5 Borko Javonovic,3,5 Robert Meryer,2 Seong-Jin Kim,7 Norman M. Greenberg,8

Immune Cells, if Rendered Insensitive to Transforming Growth Factorbeta, Can Cure Prostate Cancer

DTIC Science & Technology

2007-02-01

Robert E. Meyer,2 Shilajit Kundu,1 Michael Pins,2 Borko Javonovic,3 Timothy Kuzel,4 Seong-Jin Kim,5 Luk Van Parijs,6 Norm Smith,1 Larry Wong,1 Norman M...Zhang,1 Ximing Yang,2,5 Shilajit D. Kundu,1 Michael Pins,2,5 Borko Javonovic,3,5 Robert Meryer,2 Seong-Jin Kim,7 Norman M. Greenberg,8 Timothy Kuzel

Comparison of the algorithms classifying the ABC and GCB subtypes in diffuse large B-cell lymphoma.

PubMed

Boltežar, Lučka; Prevodnik, Veronika Kloboves; Perme, Maja Pohar; Gašljević, Gorana; Novaković, Barbara Jezeršek

2018-05-01

Different immunohistochemical algorithms for the classification of the activated B-cell (ABC) and germinal center B-cell (GCB) subtypes of diffuse large B-cell lymphoma (DLBCL) are applied in different laboratories. In the present study, 127 patients with DLCBL were investigated, all treated with rituximab and cyclophosphamide, hydroxydaunorubicin, oncovin and prednisone (CHOP) or CHOP-like regimens between April 2004 and December 2010. Multi-tumor tissue microarrays were prepared and were tested according to 4 algorithms: Hans; modified Hans; Choi; and modified Choi. For 39 patients, the flow cytometric quantification of CD19 and CD20 antigen expression was performed and the level of expression presented as molecules of equivalent soluble fluorochrome units. The Choi algorithm was demonstrated to be prognostic for OS and classified patients into the GCB subgroup with an HR of 0.91. No difference in the expression of the CD19 antigen between the ABC and GCB groups was observed, but the ABC subtype exhibited a decreased expression of the CD20 antigen compared with the GCB subtype.

Joint Institute for Nanoscience Annual Report 2003

DOE Office of Scientific and Technical Information (OSTI.GOV)

Baer, Donald R.; Campbell, Charles

2004-02-01

The Joint Institute for Nanoscience (JIN) is a cooperative venture of the University of Washington and Pacific Northwest National Laboratory to encourage and enhance high-impact and high-quality nanoscience and nanotechnology of all types. This first annual report for the JIN summarizes activities beginning in 2001 and ending at the close of fiscal year 2003 and therefore represents somewhat less than two years of activities. Major portions of the JIN resources are dedicated to funding graduate students and postdoctoral research associates to perform research in collaborations jointly directed by Pacific Northwest National Laboratory (PNNL) staff scientists and University of Washington (UW)more » professors. These fellowships were awarded on the basis of applications that included research proposals. JIN co-sponsors an annual Nanoscale Science and Technology Workshop held in Seattle. In addition to involving PNNL staff in various UW nanoscience courses and seminars, a National Science Foundation grant Development of UW-PNL Collaborative Curriculums in Nano-Science and Technology has allowed the development of three intensive short courses that are taught by UW faculty, PNNL staff, and faculty from other institutions, including Washington State University, the University of Idaho, Stanford University, and the University of Alaska. The initial JIN agreement recognized that expansion of cooperation beyond UW and PNNL would be highly valuable. Starting in early 2003, efforts were initiated to form a regional communication link called the Northwest Nanoscience and Nanotechnology Network (N₄). In concept, N₄ is a tool to encourage communication and help identify regional resources and nanoscience and technology activities.« less

Cavitation Induced Structural and Neural Damage in Live Brain Tissue Slices: Relevance to TBI

DTIC Science & Technology

2014-09-29

Conference & Exposition on Experimental &Applied Mechanics , Mohegan Sun , Uncasville, Connecticut, June 13-16, 2011. (c) Presentations Number of...Presentations: Non Peer-Reviewed Conference Proceeding publications (other than abstracts): 08/23/2012 13.00 Received Paper Sung Jin Lee, Jingjing Sun ...abstracts): (d) Manuscripts 08/31/2011 08/31/2011 Received Paper 3.00 6.00 Sung Jin Lee, Jingjing Sun , Michael King , Huikai Xie , Malisa Sarntinoranont1

RF Characteristics of Mica-Z Wireless Sensor Network Motes

DTIC Science & Technology

2006-03-01

MICA-Z WIRELESS SENSOR NETWORK MOTES by Swee Jin Koh March 2006 Thesis Advisor: Gurminder Singh Thesis Co-Advisor: John C...Mica-Z Wireless Sensor Network Motes 6. AUTHOR(S) : Swee Jin Koh 5. FUNDING NUMBERS 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Naval...ad-hoc deployment. 15. NUMBER OF PAGES 83 14. SUBJECT TERMS: Wireless Sensor Network 16. PRICE CODE 17. SECURITY CLASSIFICATION OF

Retraction RETRACTION of "Methylation of the RASSFIA promoter in breast cancer" by Y. Ji, H.H. Jin, M.D. Wang, W.X. Cao, J.L. Bao - Genet. Mol. Res. 15 (2): gmr.15028261 (2016) - DOI: 10.4238/gmr.15028261.

PubMed

Ji, Y; Jin, H H; Wang, M D; Cao, W X; Bao, J L

2016-10-07

The retracted article is: Ji Y, Jin HH, Wang MD, Cao WX, et al. (2016). Methylation of the RASSFIA promoter in breast cancer. Genet. Mol. Res. 15: gmr.15028261. There are significant parts of this article (particularly, in the discussion section) that are copied from "Methylation of HIN-1, RASSF1A, RIL and CDH13 in breast cancer is associated with clinical characteristics, but only RASSF1A methylation is associated with outcome", by Jia Xu, Priya B Shetty, Weiwei Feng, Carol Chenault, Robert C Bast Jr, Jean-Pierre J Issa, Susan G Hilsenbeck and Yinhua Yu, published in BMC Cancer 2012; 12: 243. DOI: 10.1186/1471-2407-12-243. The first paragraphs of both discussions are identical. This is concerning. The abstract and introduction sections have much of their text plagiarized. Overall, there is high plagiarism detected. The GMR editorial staff was alerted and after a thorough investigation, we have strong reason to believe that the peer review process was failure and, after review and contacting the authors, the editors of Genetics and Molecular Research decided to retract the article in accordance with the recommendations of the Committee on Publication Ethics (COPE). The authors and their institutions were advised of this serious breach of ethics.

Taxonomic study on the genus Fissicepheus (Acari: Oribatida: Otocepheidae) from China.

PubMed

Zheng, Li-Hao; Chen, Jun

2018-04-18

Four new species of the genus Fissicepheus Balogh Mahunka, 1967 from China are described on the basis of adults: Fissicepheus (Fissicepheus) aokii sp. nov., types from Shanxi Province, F. (F.) combicondylus sp. nov., from Guangdong Province, F. (F.) confragosus sp. nov., from Sichuan Province, and F. wangae sp. nov. from Beijing City. A revised generic diagnosis and a key to the 26 known species worldwide of Fissicepheus are provided. Compared with the diagnosis of the subgenus F. (Psammocepheus) Aoki, 1970, F. (P.) haradai Choi, 1986 is moved to the nominotypical subgenus: F. (F.) haradai Choi, 1986.

Spatial Control of Crystal Texture by Laser DMD Process

DTIC Science & Technology

2009-02-01

Parallel to rolling direction 1120 827 31 205 24 Matweb In718 filler material 1140 414 Charpy Impact Energy (J) Hardness (HRC) Tensile strength (Mpa...J. Choi, K. Nagarathnam, J. Koch, and D. Hetzner, “The direct metal deposition of H13 tool steel for 3-D components,” JOM, 49(5), 1997, 55-60. 4. M...Transactions A, 36A, 2005, 3397-3406. 6. Y. Hua and J. Choi, “Feedback control effects on dimensions and defects of H13 tool steel by DMD process,” J. of Laser Applications, 17(2), 2005, 117-125. 412

75 FR 65625 - Osprey II, LLC; Notice of Preliminary Permit Application Accepted for Filing and Soliciting...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-26

... study the feasibility of the 649 Water Street Project to be located on the Cobbosseecontee Stream, in.... Applicant Contact: Hoon Won, 275 River Road, P.O. Box 202, Woolwich, ME 04579; (203) 340-2517. FERC Contact...

Clinical Feasibility of Continuously Monitored Data for Heart Rate, Physical Activity, and Sleeping by Wearable Activity Trackers in Patients with Thyrotoxicosis: Protocol for a Prospective Longitudinal Observational Study.

PubMed

Lee, Jie-Eun; Lee, Dong Hwa; Oh, Tae Jung; Kim, Kyoung Min; Choi, Sung Hee; Lim, Soo; Park, Young Joo; Park, Do Joon; Jang, Hak Chul; Moon, Jae Hoon

2018-02-21

Thyrotoxicosis is a common disease caused by an excess of thyroid hormones. The prevalence of thyrotoxicosis about 2% and 70-90% of thyrotoxicosis cases are caused by Graves' disease, an autoimmune disease, which has a high recurrence rate when treated with antithyroid drugs such as methimazole or propylthiouracil. The clinical symptoms and signs of thyrotoxicosis include palpitation, weight loss, restlessness, and difficulty sleeping. Although these clinical changes in thyrotoxicosis can be detected by currently available wearable activity trackers, there have been few trials of the clinical application of wearable devices in patients with thyrotoxicosis. The aim of this study is to investigate the clinical applicability of wearable device-generated data to the management of thyrotoxicosis. We are analyzing continuously monitored data for heart rate, physical activity, and sleep in patients with thyrotoxicosis during their clinical course after treatment. Thirty thyrotoxic patients and 10 control subjects were enrolled in this study at Seoul National University Bundang Hospital. Heart rate, physical activity, and sleep are being monitored using a Fitbit Charge HR or Fitbit Charge 2. Clinical data including anthropometric measures, thyroid function test, and hyperthyroidism symptom scale are recorded. Study enrollment began in December 2016, and the intervention and follow-up phases are ongoing. The results of the data analysis are expected to be available by September 2017. This study will provide a foundational feasibility trial of the clinical applications of biosignal measurements to the differential diagnosis, prediction of clinical course, early detection of recurrence, and treatment in patients with thyrotoxicosis. ClinicalTrials.gov NCT03009357; https://clinicaltrials.gov/ct2/show/NCT03009357 (Archived by WebCite at http://www.webcitation.org/6wh4MWPm2). ©Jie-Eun Lee, Dong Hwa Lee, Tae Jung Oh, Kyoung Min Kim, Sung Hee Choi, Soo Lim, Young Joo Park, Do

Scalable, Flexible and Active Learning on Distributions

DTIC Science & Technology

2016-09-01

enthusiasm about widely varying research ideas was inspiring. Junier Oliva always knew the right way to think about something when I got stuck. Tzu -Kuo...109 Bibliography 113 iii iv Chapter 1 Introduction Traditional machine learning approaches focus on learning problems defined on...with Tzu -Kuo (TK) Huang. 2 et al. 2012; Ntampaka, Trac, Sutherland, Battaglia, et al. 2015; Jin 2016; Jin et al. 2016; Sutherland, J. B. Oliva, et al

High-Accuracy Methods for Numerical Flow Analysis Using Adaptive Non-Linear Wavelets

DTIC Science & Technology

2012-08-01

n ji n ji  , )(~ ,, Opp n jin ji  , (2-8) )(~ 2/12/1  OEE nn  , )(~ 2/12/1 OFF nn  . Also, if the flux values are discretized with...jin ji  , (3-5) )(~ 2/12/1  OEE nn  , )(~ 2/12/1 OFF nn  . Also, if the flux values are discretized with the lth order of spatial

Analysis of Transient Electromagnetic Scattering from Three Dimensional Cavities

DTIC Science & Technology

2014-01-01

New York, 2002. [24] J. Jin and J. L. Volakis, A hybrid finite element method for scattering and radiation by micro strip patch antennas and arrays...applications such as the design of cavity-backed conformal antennas and the deliberate control in the form of enhancement or reduction of radar cross...electromagnetic scattering analysis, IEEE Trans. Antennas Propagat., 50 (2002), pp. 1192–1202. [22] J. Jin, Electromagnetic scattering from large, deep, and

Prognostic significance of immunohistochemistry-based markers and algorithms in immunochemotherapy-treated diffuse large B cell lymphoma patients.

PubMed

Culpin, Rachel E; Sieniawski, Michal; Angus, Brian; Menon, Geetha K; Proctor, Stephen J; Milne, Paul; McCabe, Kate; Mainou-Fowler, Tryfonia

2013-12-01

To reassess the prognostic validity of immunohistochemical markers and algorithms identified in the CHOP era in immunochemotherapy-treated diffuse large B cell lymphoma patients. The prognostic significance of immunohistochemical markers (CD10, Bcl-6, Bcl-2, MUM1, Ki-67, CD5, GCET1, FoxP1, LMO2) and algorithms (Hans, Hans*, Muris, Choi, Choi*, Nyman, Visco-Young, Tally) was assessed using clinical diagnostic blocks taken from an unselected, population-based cohort of 190 patients treated with R-CHOP. Dichotomizing expression, low CD10 (<10%), low LMO2 (<70%) or high Bcl-2 (≥80%) predicted shorter overall survival (OS; P = 0.033, P = 0.010 and P = 0.008, respectively). High Bcl-2 (≥80%), low Bcl-6 (<60%), low GCET1 (<20%) or low LMO2 (<70%) predicted shorter progression-free survival (PFS; P = 0.001, P = 0.048, P = 0.045 and P = 0.002, respectively). The Hans, Hans* and Muris classifiers predicted OS (P = 0.022, P = 0.037 and P = 0.011) and PFS (P = 0.021, P = 0.020 and P = 0.004). The Choi, Choi* and Tally were associated with PFS (P = 0.049, P = 0.009 and P = 0.023). In multivariate analysis, the International Prognostic Index (IPI) was the only independent predictor of outcome (OS; HR: 2.60, P < 0.001 and PFS; HR: 2.91, P < 0.001). Results highlight the controversy surrounding immunohistochemistry-based algorithms in the R-CHOP era. The need for more robust markers, applicable to the clinic, for incorporation into improved prognostic systems is emphasized. © 2013 John Wiley & Sons Ltd.

The Korean-Japanese Territorial Dispute Over Dokdo/Takeshima

DTIC Science & Technology

2007-12-01

Bok-Sook Na, Soon-Sook Na, Soon-Soon Na, Kyung-Sook Na, Jin-Sook Na, and Hye -Jin Na, and twelve nephews and nieces, and my brother-in-law, Han-Il...retreated, and the Japanese won the battle and acquired Dalny, a precious commercial harbor. Japan lost almost 5,000 troops, while the Russians lost...179 Choon-Ho Park , “Oil under Troubled Waters: The Northeast Asia Sea-Bed Controversy,” in East Asia and the Law of the

78 FR 67178 - National Institute of Dental & Craniofacial Research; Notice of Closed Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-08

... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute of Dental... clearly unwarranted invasion of personal privacy. Name of Committee: National Institute of Dental and...-Hoon, Ph.D., Scientific Review Officer, Scientific Review Branch, National Institute of Dental and...

Effect of selenium-enriched organic material amendment on selenium fraction transformation and bioavailability in soil.

PubMed

Wang, Dan; Dinh, Quang Toan; Anh Thu, Tran Thi; Zhou, Fei; Yang, Wenxiao; Wang, Mengke; Song, Weiwei; Liang, Dongli

2018-05-01

To exploit the plant byproducts from selenium (Se) biofortification and reduce environmental risk of inorganic Se fertilizer, pot experiment was conducted in this study. The effects of Se-enriched wheat (Triticum aestivum L.) straw (WS + Se) and pak choi (Brassica chinensis L.) (P + Se) amendment on organo-selenium speciation transformation in soil and its bioavailability was evaluated by pak choi uptake. The Se contents of the cultivated pak choi in treatments amended with the same amount of Se-enriched wheat straw and pak choi were 1.7 and 9.7 times in the shoots and 2.3 and 6.3 times in the roots compared with control treatment. Soil respiration rate was significantly increased after all organic material amendment in soil (p < 0.05), which accelerated the mineralization of organic materials and thus resulted in soluble Se (SOL-Se), exchangeable Se (EX-Se), and fulvic acid-bound Se (FA-Se) fraction increasing by 25.2-29.2%, 9-13.8%, and 4.92-8.28%, respectively. In addition, both Pearson correlation and cluster analysis showed that EX-Se and FA-Se were better indicators for soil Se availability in organic material amendment soils. The Marquardt-Levenberg Model well described the dynamic kinetics of FA-Se content after Se-enriched organic material amendment in soil mainly because of the mineralization of organic carbon and organo-selenium. The utilization of Se in P + Se treatment was significantly higher than those in WS + Se treatment because of the different mineralization rates and the amount of FA-Se in soil. Se-enriched organic materials amendment can not only increase the availability of selenium in soil but also avoid the waste of valuable Se source. Copyright © 2018 Elsevier Ltd. All rights reserved.

Development of km23-Based Diagnostics and Therapeutics

DTIC Science & Technology

2004-05-01

Publishers, Cancer Treatment and Research Book Series. Chap . 15, 315-327, 2004. Abstracts: Jin Q, MD, Ding W, MD, PhD, Staub CM, Gao G, MD, Mulder KM, PhD...Kluwer Academic Publishers, Cancer Treatment and Research Book Series. Chap . 15, 315-327, 2004. Ilangovan U, Ding W, Zuniga J, Wilson, CL, Hinck AP...Academic Publishers, Cancer Treatment and Research Book Series. Chap . 15, 315-327, 2004. 2. Manuscript Submitted: Jin Q. Ding W, Staub CM, Gao G, Tang Q

Interaction between Fresh and Sea Water in Tidal Influenced Navigation Channel

NASA Astrophysics Data System (ADS)

Hwang, J. H. H.; Nam-Hoon, K.

2016-02-01

Nam-Hoon, Kim 1, Jin-Hwan, Hwang 2, Hyeyun-Ku 31,2,3 Department of Civil and Environmental Engineering, Seoul National University, Republic of Korea; 1nhkim0426@snu.ac.kr; 2jinhwang@snu.ac.kr; 3hyeyun.ku@gmail.com; We have conducted field observations after freshwater discharges of sea dike during ebb tide in Geum River Estuary, Korea to understand the interaction between fresh and sea water. To measure spatial variability of the stratified flow, an Acoustic Doppler Current Profiler (ADCP) and a portable free-fall tow-yo instrument, Yoing Ocean Data Acquisition Profiler (YODA profiler) which can continuously measures three-dimensional velocity profiles and vertical profiles of the fine-scale features, respectively, within water column were used in a vessel moving at a speed of 1-2 m/s. The flow observations show the strong stratification and dispersion occurred near field region because of the ebb tide advection (Fig. 1). As moving toward the far field region, the stratification and dispersion was getting thin and weak but still remaining. The presence of mixing process between fresh and sea water was represented by the gradient Richardson Number. The mixing occurred throughout the near field region and potentially mixed in the far field region. This study have been conducted to serve as a basic research of understanding the Region Of Freshwater Influence (ROFI) in the tidal influenced navigation channel. We are going to perform a few more observations in the future. Key words: Richardson number, stratification, mixing, ROFI, ADCP, CTDFigure 1. High-resolution observation data of salinity (psu) from YODA Profiler Acknowledgement: This research was supported by grants from the Korean Ministry of Oceans and Fisheries entitled as "Developing total management system for the Keum river estuary and coast" and "Integrated management of marine environment and ecosystems around Saemangeum". We also thank to the administrative supports of Integrated Research Institute of

The Role of AKT2 in Human Breast Cancer

DTIC Science & Technology

2002-06-01

factors, Aktl becomes phosphorylated at these two serous cystadenocarcinomas , four mucinous cystadeno- residues. It has been shown that AKT2 is activated...AD Award Number: DAMD17-01-1-0397 TITLE: The Role of AKT2 in Human Breast Cancer PRINCIPAL INVESTIGATOR: Zeng Qiang Yuan, Ph.D. Jin Q. Cheng, M.D...in Human Breast Cancer DAMD17-01-1-0397 6. AUTHOR(S) Zeng Qiang Yuan, Ph.D. Jin Q. Cheng, M.D., Ph.D. 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES

76 FR 4939 - John M. Chois; Decision and Order

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-27

... practitioner, and the denial of any pending applications to renew or modify his registration, on the ground... Requested, which was addressed to him at his registered location. Since the date of service of the Order... permitted, by * * * the jurisdiction in which he practices * * * to distribute, dispense, [or] administer...

Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (85th, Miami, Florida, August 5-8, 2002). Magazine Division.

ERIC Educational Resources Information Center

2002

The Magazine Division of the proceedings contains the following 8 papers: "The Coverage of Prostate Cancer and Impotence in Four Magazines: 1991-2000" (W. Buzz Hoon); "A Content Analysis of Advertising Visuals in the Magazine Advertisements: The Roaring Twenties and the Great Depression" (Daechun An); "Do They 'Play Like…

Transcriptome Analysis and Ultrastructure Observation Reveal that Hawthorn Fruit Softening Is due to Cellulose/Hemicellulose Degradation

PubMed Central

Xu, Jiayu; Zhao, Yuhui; Zhang, Xiao; Zhang, Lijie; Hou, Yali; Dong, Wenxuan

2016-01-01

Softening, a common phenomenon in many fruits, is a well coordinated and genetically determined process. However, the process of flesh softening during ripening has rarely been described in hawthorn. In this study, we found that ‘Ruanrou Shanlihong 3 Hao’ fruits became softer during ripening, whereas ‘Qiu JinXing’ fruits remained hard. At late developmental stages, the firmness of ‘Ruanrou Shanlihong 3 Hao’ fruits rapidly declined, and that of ‘Qiu JinXing’ fruits remained essentially unchanged. According to transmission electron microscopy, the middle lamella of ‘Qiu JinXing’ and ‘Ruanrou Shanlihong 3 Hao’ fruit flesh was largely degraded as the fruits matured. Microfilaments in ‘Qiu JinXing’ flesh were arranged close together and were deep in color, whereas those in ‘Ruanrou Shanlihong 3 Hao’ fruit flesh were arranged loosely, partially degraded and light in color. RNA-Seq analysis yielded approximately 46.72 Gb of clean data and 72,837 unigenes. Galactose metabolism and pentose and glucuronate interconversions are involved in cell wall metabolism, play an important role in hawthorn texture. We identified 85 unigenes related to the cell wall between hard- and soft-fleshed hawthorn fruits. Based on data analysis and real-time PCR, we suggest that β-GAL and PE4 have important functions in early fruit softening. The genes Ffase, Gns,α-GAL, PE63, XTH, and CWP, which are involved in cell wall degradation, are responsible for the different textures of hawthorn fruits. Thus, we hypothesize that the different textures of ‘Qiu JinXing’ and ‘Ruanrou Shanlihong 3 Hao’ fruits at maturity mainly result from cellulose/hemicelluloses degradation rather than from lamella degradation. Overall, we propose that different types of hydrolytic enzymes in cells interact to degrade the cell wall, resulting in ultramicroscopic Structure changes in the cell wall and, consequently, fruit softening. These results provide fundamental insight

77 FR 1936 - Ocean Transportation Intermediary License; Applicants

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-12

...), 9333 Elm Vista Drive, 9, Downey, CA 90242, Officer: Cynthia Choi, CEO/CFO/Secretary, (Qualifying.... Steele Logistics, LLC (NVO), 10722 La Cienega Blvd., Inglewood, CA 90304, Officer: Rene N. Steele, Member...

Transition to farming more likely for small, conservative groups with property rights, but increased productivity is not essential

PubMed Central

Gallagher, Elizabeth M.; Shennan, Stephen J.; Thomas, Mark G.

2015-01-01

Theories for the origins of agriculture are still debated, with a range of different explanations offered. Computational models can be used to test these theories and explore new hypotheses; Bowles and Choi [Bowles S, Choi J-K (2013) Proc Natl Acad Sci USA 110(22):8830–8835] have developed one such model. Their model shows the coevolution of farming and farming-friendly property rights, and by including climate variability, replicates the timings for the emergence of these events seen in the archaeological record. Because the processes modeled occurred a long time ago, it can be difficult to justify exact parameter values; hence, we propose a fitting to idealized outcomes (FIO) method to explore the model’s parameter space in more detail. We have replicated the model of Bowles and Choi, and used the FIO method to identify complexities and interactions of the model previously unidentified. Our results indicate that the key parameters for the emergence of farming are group structuring, group size, conservatism, and farming-friendly property rights (lending further support to Bowles and Choi’s original proposal). We also find that although advantageous, it is not essential that farming productivity be greater than foraging productivity for farming to emerge. In addition, we highlight how model behaviors can be missed when gauging parameter sensitivity via a fix-all-but-one variation approach. PMID:26578766

Holistic Reasoning on the Other Side of the World: Validation of the Analism/Holism Scale in Mexicans

PubMed Central

Lechuga, Julia; Santos, Beatriz Maldonado; Garza-Caballero, Azenett A.; Villarreal, Ricardo

2011-01-01

The universality of cognitive processes has been called into question. Research suggests that individuals from Eastern cultures (e.g., China, Korea) when compared to individuals from Western cultures (e.g., the United States) prefer to reason holistically. This line of research has not been extended to cultural groups far removed from cultures traditionally surveyed in cross-cultural research such as Hispanics. We conducted two studies to understand: 1) the generalizability of the construct of holistic reasoning in Mexicans, and 2) the preferred reasoning style of Mexicans when compared to U.S. Americans. Results support the generalization of the factor structure of holistic reasoning as originally hypothesized by Choi, Koo, and Choi (2007). The results of Study 2 suggest that Mexicans scored higher than U.S. Americans on certain aspects of holistic reasoning. PMID:21787065

Holistic reasoning on the other side of the world: validation of the analysis-holism scale in Mexicans.

PubMed

Lechuga, Julia; Santos, Beatriz Maldonado; Garza-Caballero, Azenett A; Villarreal, Ricardo

2011-07-01

The universality of cognitive processes has been called into question. Research suggests that individuals from Eastern cultures (e.g., China, Korea) when compared to individuals from Western cultures (e.g., the United States) prefer to reason holistically. This line of research has not been extended to cultural groups far removed from cultures traditionally surveyed in cross-cultural research such as Hispanics. We conducted two studies to understand: 1) the generalizability of the construct of holistic reasoning in Mexicans, and 2) the preferred reasoning style of Mexicans when compared to U.S. Americans. Results support the generalization of the factor structure of holistic reasoning as originally hypothesized by Choi, Koo, and Choi (2007). The results of Study 2 suggest that Mexicans scored higher than U.S. Americans on certain aspects of holistic reasoning.

GaN-on-glass success

NASA Astrophysics Data System (ADS)

2011-12-01

The successful growth of GaN-based LEDs on amorphous glass avoids the size and cost limitations of a sapphire substrate, says Jun Hee Choi from the Samsung Advanced Institute of Technology in South Korea.

Trust-based Task Assignment in Military Tactical Networks

DTIC Science & Technology

2012-06-01

Decentralized   Auctions  for  Robust   Task   Allocation ,“  IEEE Trans. on Robotics, vol. 25, no. 4, pp. 912‐926, Aug. 2009.  [10] B.B. Choudhury, B.B. Biswal, and D...Choi et al. [9]  and Choudhury et al. [10] investigated market‐ based   task   allocation  algorithms for multi‐robot systems. Choi et  al. [9] proposed a... consensus ‐ based  bundle algorithm for rapid conflict‐free matching between  tasks  and robots.  Choudhury et al. [10] conducted an empirical study on a

Genetics Home Reference: Schimke immuno-osseous dysplasia

MedlinePlus

... Smithson SF, Sloan EA, Lou S, Huang Y, Choi K, Lücke T, Alpay H, André JL, Asakura Y, ... Collard L, Cordeiro I, Cormier-Daire V, Cransberg K, Cutka K, Deschenes G, Ehrich JH, Fründ S, Georgaki ...

Kansas Working Papers in Linguistics, Volume 20.

ERIC Educational Resources Information Center

Goodell, Melissa, Ed.; Choi, Dong-Ik, Ed.

1995-01-01

Papers in this volume include the following: "Evidence for Foot Structure in Hausa" (Ousseina Alidou); "Korean 'Tense' Consonants as Geminates" (Dong-Ik Choi); "Gemination Processes: Motivation, Form, and Constraints" (Mamadou Niang); "Syllable 'Sonority' Hierarchy and Pulaar Stress: A Metrical Approach"…

Investigation of Sooting in Microgravity Droplet Combustion: Fuel-Dependent Effects

NASA Technical Reports Server (NTRS)

Manzello, Samuel L.; Hua, Ming; Choi, Mun Young

1999-01-01

Kumagai and coworkers first performed microgravity droplet combustion experiments [Kumagai, 1957]. The primary goal of these early experiments were to validate simple 'd(sup 2)-law models [Spalding, 1954, Godsave, 1954] Inherent in the 'd(sup 2) -law' formulation and in the scope of the experimental observation is the neglect of sooting behavior. In fact, the influence of sooting has not received much attention until more recent works [Choi et al., 1990; Jackson et al., 1991; Jackson and Avedisian, 1994; Choi and Lee, 1996; Jackson and Avedisian, 1996; Lee et al., 1998]:. Choi and Lee measured soot volume fraction for microgravity droplet flames using full-field light extinction and subsequent tomographic inversion [Choi and Lee, 1996]. In this investigation, soot concentrations were measured for heptane droplets and it was reported that soot concentrations were considerably higher in microgravity compared to the normal gravity flame. It was reasoned that the absence of buoyancy and the effects of thermophoresis resulted in the higher soot concentrations. Lee et al. [1998] performed soot measurement experiments by varying the initial droplet diameter and found marked influence of sooting on the droplet burning behavior. There is growing sentiment that sooting in droplet combustion must no longer be neglected and that "perhaps one of the most important outstanding contributions of (micro)g droplet combustion is the observation that in the absence of asymmetrical forced and natural convection, a soot shell is formed between the droplet surface and the flame, exerting an influence on the droplet combustion response far greater than previously recognized." [Law and Faeth, 1994]. One of the methods that we are exploring to control the degree of sooting in microgravity is to use different fuels. The effect of fuel structure on sooting propensity has been investigated for over-ventilated concentric coflowing buoyant diffusion flames. (Glassman, 1996]. In these

Code Optimization for the Choi-Williams Distribution for ELINT Applications

DTIC Science & Technology

2009-12-01

Probability of Intercept N Number of Samples NPS Naval Postgraduate School SNR Signal To Noise Ratio WVD Wigner - Ville Distribution xvi THIS PAGE...Many of the optimizations developed can be applied to the computation of the Wigner - Ville distribution as well. This work is highly applicable in the...made can also be used to increase the speed at which the Wigner - Ville distribution (another signal processing algorithm) can be computed. These

Comparison of Three Methods for Generating Superhydrophobic, Superoleophobic Nylon Nonwoven Surfaces (Postprint)

DTIC Science & Technology

2011-04-01

AFRL-RX-TY-TP-2010-0076 COMPARISON OF THREE METHODS FOR GENERATING SUPERHYDROPHOBIC , SUPEROLEOPHOBIC NYLON NONWOVEN SURFACES Rahul Saraf...Generating Superhydrophobic , Superoleophobic Nylon Nonwoven Surfaces (POSTPRINT) FA8650-07-1-5916 0602102F GOVT L0 QL102006 ^Saraf, Rahul,; ^Lee, Hoon...Document contains color images. This research deals with creating a superhydrophobic /superoleophobic surface by preparing a metastable Cassie

75 FR 60124 - Ocean Transportation Intermediary License Applicants

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-29

... FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License Applicants Notice is hereby... license as a Non-Vessel-Operating Common Carrier (NVO) and/or Ocean Freight Forwarder (OFF)--Ocean..., Application Type: New OFF License Myunghe Choi dba World Express Shipping (NVO), 4733 Torrance Blvd., 187...

MATHEMATICAL ANALYSIS OF PARTICLE TRANSPORT AND DEPOSITION IN HUMAN LUNGS

EPA Science Inventory

MATHEMATICAL ANALYSIS OF PARTICLE TRANSPORT AND DEPOSITION IN HUMAN LUNGS. Jung-il Choi*, Center for Environmental Medicine, University of North Carolina, Chapel Hill, NC 27599; C. S. Kim, USEPA National Health and Environmental Effects Research Lab. RTP, NC 27711

Partic...

Effects of full-facility variable tolling on traveler behavior : evidence from a panel study of the SR-520 corridor in Seattle.

DOT National Transportation Integrated Search

2014-10-01

This paper uses a two-stage panel survey approach, with roughly 2,000 respondent households, to analyze the impacts of a federally sponsored variable tolling program on SR-520 in the Seattle region. The focus is on corridor users daily travel choi...

Contrast media enhancement reduction predicts tumor response to presurgical molecular-targeting therapy in patients with advanced renal cell carcinoma.

PubMed

Hosogoe, Shogo; Hatakeyama, Shingo; Kusaka, Ayumu; Hamano, Itsuto; Tanaka, Yoshimi; Hagiwara, Kazuhisa; Hirai, Hideaki; Morohashi, Satoko; Kijima, Hiroshi; Yamamoto, Hayato; Tobisawa, Yuki; Yoneyama, Tohru; Yoneyama, Takahiro; Hashimoto, Yasuhiro; Koie, Takuya; Ohyama, Chikara

2017-07-25

A quantitative tumor response evaluation to molecular-targeting agents in advanced renal cell carcinoma (RCC) is debatable. We aimed to evaluate the relationship between radiologic tumor response and pathological response in patients with advanced RCC who underwent presurgical therapy. Of 34 patients, 31 underwent scheduled radical nephrectomy. Presurgical therapy agents included axitinib (n = 26), everolimus (n = 3), sunitinib (n = 1), and axitinib followed by temsirolimus (n = 1). The major presurgical treatment-related adverse event was grade 2 or 3 hypertension (44%). The median radiologic tumor response by RECIST, Choi, and CMER were -19%, -24%, and -49%, respectively. Among the radiologic tumor response tests, CMER showed a higher association with tumor necrosis in surgical specimens than others. Ki67/MIB1 status was significantly decreased in surgical specimens than in biopsy specimens. The magnitude of the slope of the regression line associated with the tumor necrosis percentage was greater in CMER than in Choi and RECIST. Between March 2012 and December 2016, we prospectively enrolled 34 locally advanced and/or metastatic RCC who underwent presurgical molecular-targeting therapy followed by radical nephrectomy. Primary endpoint was comparison of radiologic tumor response among Response Evaluation Criteria in Solid Tumors (RECIST), Choi, and contrast media enhancement reduction (CMER). Secondary endpoint included pathological downstaging, treatment related adverse events, postoperative complications, Ki67/MIB1 status, and tumor necrosis. CMER may predict tumor response after presurgical molecular-targeting therapy. Larger prospective studies are needed to develop an optimal tumor response evaluation for molecular-targeting therapy.

Protection by Purines in Toxin Models of Parkinson’s Disease

DTIC Science & Technology

2014-08-01

Nucleoside transport and metabolism in erythrocytes from the Yucatan miniature pig. Evidence that inosine functions as an in vivo energy substrate...BJ, Choi HK. Prevalence of gout and hyperuricemia in the us general population: The national health and nutrition examination survey 2007–2008

An Exploration of the Roles of Communication Apprehension, Online Technology Self-Efficacy, and Retention in an Online Public Speaking Course

ERIC Educational Resources Information Center

Stout, Carla Sulivant

2012-01-01

Although the growth rate of online learning continues to increase, online courses are yielding higher attrition rates compared to traditional learning courses (Carswell, Thomas, Petre, Price, & Richards, 2000; Clark & Jones, 2001; Nash, 2005; Park & Choi, 2009). The literature has previously linked online technology self-efficacy and…

Linking the Physicochemical Properities of Titania with Its Biocidal Properities

EPA Science Inventory

LINKING THE PHYSICOCHEMICAL PROPERTIES OF TITANIA WITH ITS BIOCIDAL PROPERTIES. C. Han1, L. Putvin2, M. Pelaez1, H. Zamankhan3, H. Choi3, D. Betancourt4a, D. Dionysiou1. B. Veronesi4b, 1 Department of Biomedical, Chemical and Environmental Engineering, University of Cincinnati...

The Genomic Actions and Functional Implications of Nuclear PRLr in Human Breast Carcinoma

DTIC Science & Technology

2010-03-01

pregnant mice; loss of this process may contribute to 171 gestational diabetes mellitus (Karnik, et al. 2007). 172 Ingenuity Pathway Analysis (IPA...of pancreatic beta-cells in pregnant mice and promotes gestational 403 diabetes mellitus . Science 318 806-809. 404 Kim J, Choi TG, Ding Y, Kim Y, Ha

Demonized No More: The Spiritual Journeys and Spaces of Black Gay Male College Students at Predominantly White Institutions

ERIC Educational Resources Information Center

Means, Darris R.

2014-01-01

Spirituality plays a significant role in the lives of college students (Astin, Astin, & Lindholm, 2011; Bryant, Choi, & Yasuno, 2003; Chickering, 2006; Parks, 2000). However, Black gay males are uniquely positioned with regards to spirituality given how race, gender, and sexual orientation are generally perceived and experienced in the…

"Speaking Back" from the English Periphery: Art-Work in a South Korean High School English Classroom

ERIC Educational Resources Information Center

Craig, Martin; Porter, Curt

2014-01-01

South Korean English language teaching (ELT) has typically been represented as an arena dominated by excessive competition, test preparation, and the mastery of linguistic forms (Choi & Park, 2013; Park, 2009). These notions have been compounded by stereotypical depictions of Korean students as passive learners incapable of critical thinking…

Attack pattern of Platypus koryoensis (Coleoptera: Curculionidae: Platypodidae) in relation to crown dieback of Mongolian oak in Korea

Treesearch

Jung-Su Lee; Robert A. Haack; Won Il. Choi

2011-01-01

The ambrosia beetle, Platypus koryoensis (Murayama), vectors the Korean oak wilt (KOW) pathogen, Raffaelea quercus-mongolicae K.H. Kim, Y.J. Choi, & H.D. Shin, in Korea, which is highly lethal to Mongolian oak, Quercus mongolica Fisch., and is considered a major threat to forest ecosystem health. We...

Comment on ''Theory of collisions between an atom and a diatomic molecule in the body-fixed coordinate system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schatz, G.C.; Kuppermann, A.

1979-03-15

It is shown that the phase factor i/sup J+j+l/ omitted in a theory of atom-diatom monreactive scattering formulated by Schatz and Kupperman but included in the Choi, Poe, and Tang theory does not lead to errors in the analysis of te (H,H/sub 2/) system.

Development of a Semi-Autonomous Underwater Vehicle for Intervention Missions (SAUVIM Phase III-C)

DTIC Science & Technology

2010-01-28

James Fein from ONR, Mr. Chris Hillenbrand became the ONR Program Officer for the SAUVIM project. In 2002, Dr. David Drumheller became the new ONR...Gary McMurtry, Dr. Song K. Choi & Mr. Oliver T. Easterday Past Personnel: Mr. Yann Douyere, Mr. Alan Parsa & Mr. Max D. Cremer Objectives The

Invited Reaction: Influences of Formal Learning, Personal Learning Orientation, and Supportive Learning Environment on Informal Learning

ERIC Educational Resources Information Center

Cseh, Maria; Manikoth, Nisha N.

2011-01-01

As the authors of the preceding article (Choi and Jacobs, 2011) have noted, the workplace learning literature shows evidence of the complementary and integrated nature of formal and informal learning in the development of employee competencies. The importance of supportive learning environments in the workplace and of employees' personal learning…

Promoting Creativity in the Kitchen: Digital Lessons from the Learning Environment

ERIC Educational Resources Information Center

Surgenor, Dawn; McMahon-Beattie, Una S. M.; Burns, Amy; Hollywood, Lynsey E.

2016-01-01

Creativity and learning are heightened when individuals are exposed to problem-solving activity (Y. Cho, Chung, Choi, Sea, & Baek, 2013); however, while creativity has historically been promoted in schools, educationalists experience difficulty in integrating it meaningfully to the curriculum (Y. Cho et al., 2013). This is relevant in terms of…

Conversion of DST Group Shape Optimisation Software for Increased Portability across Computing Platforms

DTIC Science & Technology

2016-05-01

reduction achieved is small due to the starting shape being near optimal. The general arrangement and x-y coordinate system are shown in Figure 23...Optimization, Vol. 28, pp. 55–68, 2004. [3] M Heller, J Calero, S Barter , RJ Wescott, J Choi. Fatigue life extension program for LAU-7 missile launcher

Resilient Excellence: Challenges Faced by Trailblazing Women in U.S. Sport Psychology

ERIC Educational Resources Information Center

Whaley, Diane E.; Krane, Vikki

2012-01-01

Consistent with other sciences (e.g., Kass-Simon, 1993; Tang, 2006), the field of kinesiology has been called a "masculine domain," which has an institutionalized culture biased against women (Brackenridge, Mutrie, & Choi, 2005). This paper represents the second part of a larger project that examined the life histories of eight trailblazing women…

Measurement Musings.

ERIC Educational Resources Information Center

Fisher, William P., Jr.; Choi, Ellie; Fisher, William P.; Stenner, A. Jackson; Horabin, Ivan; Wright, Benjamin D.

1998-01-01

Comments on measurement aspects are presented in discussions of (1) methodology and morality (W. P. Fisher); (2) Rasch measurement (E. Choi); (3) novel wisdom of the Rasch approach (W. P. Fisher); (4) development of construct definition and calibration (A. J. Stenner and I. Horabin); and (5) origin of dimensions (B. D. Wright). (SLD)

Multi-Target/Multi-Sensor Tracking using Only Range and Doppler Measurements

DTIC Science & Technology

2009-04-01

I+1) k ) represents a global maximum, given the Gaussian components used in our model, and given that P(I) has been fixed using parameter values...on Pattern Analysis and Machine Intelligence, 24 (2002), 381—396. [37] Perlovsky, L. I., Plum, C. P., Franchi , P. R., Tichovolsky, E. J., Choi, D. S

A Review Of The United States Government’s Status Quo North Korean Foreign Policy Approach And Reasons For Change

DTIC Science & Technology

2016-02-16

unity over South China Sea, Yahoo News, Jan 2016. http://news.yahoo.com/kerry-press-china-over-north-korea- urge-asean-014102596.html 38 Brent Choi...34 Yahoo News. Jan 24, 2016. http://news.yahoo.com/kerry-press-china-over- north-korea-urge-asean-014102596.html (accessed Jan 24, 2016). Bunn, M. Elaine

Fetal Alcohol Exposure Reduces Adult Brain Plasticity. Science Briefs

ERIC Educational Resources Information Center

National Scientific Council on the Developing Child, 2007

2007-01-01

"Science Briefs" summarize the findings and implications of a recent study in basic science or clinical research. This Brief summarizes the findings and implications of "Moderate Fetal Alcohol Exposure Impairs the Neurogenic Response to an Enriched Environment in Adult Mice" (I. Y. Choi; A. M. Allan; and L. A. Cunningham). Observations of mice…

Genetics Home Reference: Aicardi syndrome

MedlinePlus

... 1080/13816810802320209. Citation on PubMed Eble TN, Sutton VR, Sangi-Haghpeykar H, Wang X, Jin W, Lewis ... Free article on PubMed Central Glasmacher MA, Sutton VR, Hopkins B, Eble T, Lewis RA, Park Parsons ...

Continuous-Tone Electrostatic Electrography

DTIC Science & Technology

1948-09-15

selected as "being of greatest impor- tance: (l) exposure speed equivalent to 50 Westen» (2) high- quality continuous-tone reproduction, and...the developing or ’the fixing techniques» (10) Uniformity of Quality of Plates or Pilm from 3atch to Batch This cannot be considered until...directly to tho electrically cöhductivo hacking of the plato. This hacking is groundod aftor tho plate surfaco lias hoon chargod under corona

77 FR 44310 - Quarterly Publication of Individuals, Who Have Chosen To Expatriate, as Required by Section 6039G

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-27

... JACINTA YEUNG CHEONG CHANG MICHAEL YIO-HOW CHENG NICOLAS VINCENT CHI TELLY TAI HSUAN CHINOY SAMIR MUSTAPHA... TONJA YVONNE SU JIN CHIN SU XIAOBO SARA SHAO SUEN SAMSON C. L. SY KEVIN NEIL TAN LAI HING THARALDSEN...

Some composition formulae for the M-S-M fractional integral operator with the multi-index Mittag-Leffler functions

NASA Astrophysics Data System (ADS)

Jain, Shilpi; Agarwal, Praveen; Kıymaz, I. Onur; ćetinkaya, Ayá¹£egül

2018-01-01

Authors presented some composition formulae for the Marichev-Saigo-Maeda (M-S-M) fractional integral operator with the multi-index Mittag-Leffler functions. Our results are generalizes the results obtained by Choi and Agarwal [3]. Here, we record some particular cases of our main result. Finally, we obtain Laplace transforms of the composition formulae.

Alpha trimmed correlation for touchless finger image mosaicing

NASA Astrophysics Data System (ADS)

Rao, Shishir P.; Rajendran, Rahul; Agaian, Sos S.; Mulawka, Marzena Mary Ann

2016-05-01

In this paper, a novel technique to mosaic multiview contactless finger images is presented. This technique makes use of different correlation methods, such as, the Alpha-trimmed correlation, Pearson's correlation [1], Kendall's correlation [2], and Spearman's correlation [2], to combine multiple views of the finger. The key contributions of the algorithm are: 1) stitches images more accurately, 2) provides better image fusion effects, 3) has better visual effect on the overall image, and 4) is more reliable. The extensive computer simulations show that the proposed method produces better or comparable stitched images than several state-of-the-art methods, such as those presented by Feng Liu [3], K Choi [4], H Choi [5], and G Parziale [6]. In addition, we also compare various correlation techniques with the correlation method mentioned in [3] and analyze the output. In the future, this method can be extended to obtain a 3D model of the finger using multiple views of the finger, and help in generating scenic panoramic images and underwater 360-degree panoramas.

The effects of LED illumination spectra and intensity on carotenoid content in Brassicaceae microgreens.

PubMed

Brazaitytė, Aušra; Sakalauskienė, Sandra; Samuolienė, Giedrė; Jankauskienė, Julė; Viršilė, Akvilė; Novičkovas, Algirdas; Sirtautas, Ramūnas; Miliauskienė, Jurga; Vaštakaitė, Viktorija; Dabašinskas, Laurynas; Duchovskis, Pavelas

2015-04-15

The objective of this study was to evaluate the effects of irradiance levels and spectra produced by solid-state light-emitting diodes (LEDs) on carotenoid content and composition changes in Brassicaceae microgreens. A system of five high-power, solid-state lighting modules with standard 447-, 638-, 665-, and 731-nm LEDs was used in the experiments. Two experiments were performed: (1) evaluation of LED irradiance levels of 545, 440, 330, 220, and 110 μmol m(-2) s(-1) photosynthetically active flux density (PPFD) and (2) evaluation of the effects of 520-, 595-, and 622-nm LEDs supplemental to the standard set of LEDs. Concentrations of various carotenoids in red pak choi and tatsoi were higher under illumination of 330-440 μmol m(-2) s(-1) and at 110-220 μmol m(-2) s(-1) in mustard. All supplemental wavelengths increased total carotenoid content in mustard but decreased it in red pak choi. Carotenoid content increased in tatsoi under supplemental yellow light. Copyright © 2014 Elsevier Ltd. All rights reserved.

Reduced Uncertainties in Health Impacts and Radiative Forcing Estimates in Winter Haze in eastern China through constraints of surface PM2.5 predictions

NASA Astrophysics Data System (ADS)

Gao, M.; Saide, P. E.; Xin, J.; Wang, Y.; Liu, Z.; Wang, Z.; Pagowski, M.; Guttikunda, S. K.; Carmichael, G. R.

2016-12-01

The Gridpoint Statistical Interpolation (GSI) Three-Dimensional Variational (3DVAR) data assimilation system is extended to treat the MOSAIC aerosol model in WRF-Chem, and to be capable of assimilating surface PM2.5 concentrations. The coupled GSI-WRF-Chem system is applied to reproduce aerosol levels over China during an extremely polluted winter month, January 2013. After assimilating surface PM2.5 concentrations, the correlation coefficients between observations and model results averaged over the assimilated sites are improved from 0.67 to 0.94. At non-assimilated sites, improvements are also found in PM2.5, PM10 and AOD predictions. Using the constrained aerosol fields, we estimate that the PM2.5 concentrations in January 2013 might cause 7550 premature deaths in Jing-Jin-Ji areas, and 113.9 million (92.1% of Jing-Jin-Ji population) people in Jing-Jin-Ji are exposed to unhealthy air (monthly averaged PM2.5 concentration over 75µg/m3). We also estimate that the daytime monthly mean anthropogenic aerosol radiative forcing (ARF) to be -29.9W/m2 at the surface, 27.0W/m2 inside the atmosphere, and -2.9W/m2 at the top of the atmosphere. Our estimates reduce the previously reported overestimations along Yangtze River region and underestimations in North China. This system will also be beneficial for more reliable air quality forecasts in China.

Characterization of Gas-Hydrate Sediment: In Situ Evaluation of Hydrate Saturation in Pores of Pressured Sedimental Samples

NASA Astrophysics Data System (ADS)

Jin, Y.; Konno, Y.; Kida, M.; Nagao, J.

2014-12-01

Hydrate saturation of gas-hydrate bearing sediment is a key of gas production from natural gas-hydrate reservoir. Developable natural gas-hydrates by conventional gas/oil production apparatus almost exist in unconsolidated sedimental layer. Generally, hydrate saturations of sedimental samples are directly estimated by volume of gas generated from dissociation of gas hydrates in pore spaces, porosity data and volume of the sediments. Furthermore, hydrate saturation can be also assessed using velocity of P-wave through sedimental samples. Nevertheless, hydrate saturation would be changed by morphological variations (grain-coating, cementing and pore-filling model) of gas hydrates in pore spaces. Jin et al.[1,2] recently observed the O-H stretching bands of H2O molecules of methane hydrate in porous media using an attenuated total reflection IR (ATR-IR) spectra. They observed in situ hydrate formation/dissociation process in sandy samples (Tohoku Keisya number 8, grain size of ca. 110 μm). In this presentation, we present IR spectroscopy approach to in situ evaluation of hydrate saturation of pressured gas-hydrate sediments. This work was supported by funding from the Research Consortium for Methane Hydrate Resources in Japan (MH21 Research Consortium) planned by the Ministry of Economy, Trade and Industry (METI), Japan. [1] Jin, Y.; Konno, Y.; Nagao, J. Energy Fules, 2012, 26, 2242-2247. [2] Jin, Y.; Oyama, H.; Nagao, J. Jpn. J. Appl. Phys. 2009, 48, No. 108001.

Spring Research Festival and NICBR Collaboration Winners Announced | Poster

Cancer.gov

By Carolynne Keenan, Contributing Writer, and Ashley DeVine, Staff Writer The winners of the 2014 Spring Research Festival (SRF), held May 7 and 8, were recognized on July 2, and included 20 NCI at Frederick researchers: Matthew Anderson, Victor Ayala, Matt Bess, Cristina Bergamaschi, Charlotte Choi, Rami Doueiri, Laura Guasch Pamies, Diana Haines, Saadia Iftikhar, Maria

Cumulative Viral Load and Virologic Decay Patterns after Antiretroviral Therapy in HIV-Infected Subjects Influence CD4 Recovery and AIDS

DTIC Science & Technology

2011-05-20

study). The Antiproteases Cohorte Agence Nationale de Recherches sur le SIDA EP 11 study. J Infect Dis 186: 710–714. 8. Hermankova M, Ray SC, Ruff C... Sida (ANRS) CO3 Aquitaine Cohort. Clin Infect Dis 49: 1109–1116. 59. Choi AI, Shlipak MG, Hunt PW, Martin JN, Deeks SG (2009) HIV-infected persons

Decentralized Planning for Autonomous Agents Cooperating in Complex Missions

DTIC Science & Technology

2010-09-01

Consensus - based decentralized auctions for robust task allocation ," IEEE Transactions on Robotics...Robotics, vol. 24, pp. 209-222, 2006. [44] H.-L. Choi, L. Brunet, and J. P. How, " Consensus - based decentralized auctions for robust task allocation ...2003. 123 [31] L. Brunet, " Consensus - Based Auctions for Decentralized Task Assignment," Master’s thesis, Dept.

State University of New York Institute of Technology (SUNYIT) Visiting Scholars Program

DTIC Science & Technology

2013-05-01

team members, and build the necessary backend metal interconnections. APPROVED FOR PUBLIC RELEASE; DISTRIBUTION UNLIMITED 4 Baek-Young Choi...Cooperative and Opportunistic Mobile Cloud for Energy Efficient Positioning; Department of Computer Science Electrical Engineering, University of...Missouri - Kansas City The fast growing popularity of smartphones and tablets enables us the use of various intelligent mobile applications. As many of

Functionalization of Carbon Nanotubes via Electrophilic Substitution Reaction in Polyphosphoric Acid

DTIC Science & Technology

2006-07-26

1 Title of proposed research: Functionalization of Carbon Nanotubes via Electrophilic Substitution Reaction in Polyphosphoric Acid Proposer: Jong...Choi, J.-Y.; Tan, L.-S.; Baek, J.-B. “Functionalization of carbon nanotubes via electrophilic substitution reaction in polyphosphoric acid” AFOSR...2006 4. TITLE AND SUBTITLE Functionalization of carbon nanotubes via electrophilic substitution reaction in polyphosphoric acid 5a. CONTRACT

Autonomous Inter-Task Transfer in Reinforcement Learning Domains

DTIC Science & Technology

2008-08-01

Twentieth International Joint Conference on Artificial Intelli - gence, 2007. 304 Fumihide Tanaka and Masayuki Yamamura. Multitask reinforcement learning...Functions . . . . . . . . . . . . . . . . . . . . . . 17 2.2.3 Artificial Neural Networks . . . . . . . . . . . . . . . . . . . . 18 2.2.4 Instance-based...tures [Laird et al., 1986, Choi et al., 2007]. However, TL for RL tasks has only recently been gaining attention in the artificial intelligence

Measurement and Modeling of Ecosystem Risk and Recovery for In Situ Treatment of Contaminated Sediments

DTIC Science & Technology

2013-08-01

Hydrocarbons in Petroleum- Impacted Sediments." Environmental Science & Technology 47(2): 1024-1032. Choi, Y., Y. M. Cho, et al. (2013). "Measurement and...4020 9. SPONSORING / MONITORING AGENCY NAME(S) AND ADDRESS(ES) Strategic Environmental Research and Development...was prepared under contract to the Department of Defense Strategic Environmental Research and Development Program (SERDP). The publication of this

Graphene Synthesis and Characterization

DTIC Science & Technology

2015-04-08

for synthesis electrochemical. - A Scanning Electron Microscope (SEM) (EVO MA from Carl Zeiss). 6 6. RESULTS AND...5, 2332-2339, 2011, High-Quality Thin graphene films from fast electrochemical exfoliation. [13] Da Hee Jung , Cheong Kang, Ji Eun Nam, Jin-Seok Kim

An Unsupervised Method for Uncovering Morphological Chains (Open Access, Publisher’s Version)

DTIC Science & Technology

2015-03-08

Consortium. Marco Baroni, Johannes Matiasek, and Harald Trost. 2002. Unsupervised discovery of morphologically re- lated words based on orthographic and...Better word representations with re- cursive neural networks for morphology. In CoNLL, Sofia, Bulgaria. Mohamed Maamouri, Ann Bies, Hubert Jin, and Tim

AFRC2016-0054-528

NASA Image and Video Library

2016-02-27

Sam Choi and Naiara Pinto observe Google Earth overlaid with in almost real time what the synthetic aperture radar is mapping from the C-20A aircraft. Researchers were in the sky and on the ground to take measurements of plant mass, distribution of trees, shrubs and ground cover and the diversity of plants and how much carbon is absorbed by them.

Wavelet-Based Signal Processing for Monitoring Discomfort and Fatigue

DTIC Science & Technology

2008-06-01

Wigner - Ville distribution ( WVD ), the short-time Fourier transform (STFT) or spectrogram, the Choi-Williams distribution (CWD), the smoothed pseudo Wigner ...has the advantage of being computationally less expensive than other standard techniques, such as the Wigner - Ville distribution ( WVD ), the spectrogram...slopes derived from the spectrogram and the smoothed pseudo Wigner - Ville distribution . Furthermore, slopes derived from the filter bank

Case Study of the U.S. Army’s Should-Cost Management Implementation

DTIC Science & Technology

2013-12-03

and Pelvic Protection Systems (PPS). After graduating from the Naval Postgraduate School, Major Choi will be assigned to the U.S. Army...Systems PMO Product/Project/Program Management Office PMT Program Management Training POA&M Plan of Action and Milestones POE Program Office...Intelligence, Electronic Warfare and Sensors  PEO Simulation, Training , and Instrumentation  JPEO Chemical and Biological Defense The researcher

Electromagnetic Simulations for an Axisymmetric Gregorian Reflector System for a Space Deployed Inflatable Antenna

DTIC Science & Technology

2016-01-22

Q. J. Wei, S. Pan, S. Mohan, and S. Seager, Inflatable antenna for CubeSat : fabrication, deployment and results of experimental tests, 2014 IEEE...Aerospace Conference, pp. 1- 12. [8] A. Babuscia, T. Choi, C. Lee, and K-M. Cheung, Inflatable antennas and arrays for interplanetary communication using CubeSats and SmallSats, 2015 IEEE Aerospace Conference, pp. 1-9.

Superoleophobic Surfaces through Control of Sprayed-on Stochastic Topography (Pre-Print)

DTIC Science & Technology

2012-05-01

Tuteja, A.; Choi, W.; McKinley, G. H.; Cohen, R. E.; Rubner, M. F., Design Parameters for Superhydrophobicity and Superoleophobicity. MRS Bull. 2008...Surfaces. Langmuir 2010, 26, 4027-4035. 5. Bhushan, B.; Jung, Y. C., Natural and biomimetic artificial surfaces for superhydrophobicity , self-cleaning...Mater. 2009, 21, 2190-2195. 9. Nosonovsky, M.; Bhushan, B., Superhydrophobic surfaces and emerging applications: Non- adhesion, energy, green

Lansdale, Magsaysay, America and the Philippines: A Case Study of Limited Intervention Counterinsurgency

DTIC Science & Technology

2012-12-14

assess the implications of empathy within the context of this case study, and because this is not a paper on leadership theory , a working definition...5Jaepil Choi, “A Motivational Theory of Charismatic Leadership: Envisioning, Empathy, and Empowerment,” Journal...by Charles Stuart Kennedy (June 1989), ADST/CRS. 101Central Intelligence Agency, The Current Situation in the Philippines, 30 March 1949, CIA

A Comparison of Intrathecal and Epidural Analgesia and Its Effect on Length of Labor

DTIC Science & Technology

1997-09-10

time of delivery (Chestnut, Vandewalker, Owen, Bates, & Choi, 1987 ). Epidural or intiathecal injection of opioids has the potential to provide selective...exists pertaining to this issue (Miller, DeVore, & Eisler , 1993). Selective opioid analgesia whether epidural or intrathecal has also resulted in...of contraction of the utems and the pressure generated by these contractions (Miller, DeVore, & Eisler , 1993). Progress of labor: Increasing

An Exploration of the Lived Experiences of Year Six Children on a Residential Trip to Normandy

ERIC Educational Resources Information Center

Green, Michael

2017-01-01

Over the last decade, a plethora of research has been undertaken into learning outside the classroom and its resultant benefits on pupils [Dillon, J., M. Rickinson, K. Teamey, M. Morris, M. Y. Choi, D. Sanders, and P. Benefield. 2006. "The Value of Outdoor Learning: Evidence from Research in the UK and Elsewhere." "School Science…

Integrated Intelligence: Robot Instruction via Interactive Grounded Learning

DTIC Science & Technology

2016-02-14

ADDRESS (ES) U.S. Army Research Office P.O. Box 12211 Research Triangle Park, NC 27709-2211 Robotics; Natural Language Processing ; Grounded Language ...Logical Forms for Referring Expression Generation, Emperical Methods in Natural Language Processing (EMNLP). 18-OCT-13, . : , Tom Kwiatkowska, Eunsol...Choi, Yoav Artzi, Luke Zettlemoyer. Scaling Semantic Parsers with On-the-fly Ontology Matching, Emperical Methods in Natural Langauge Processing

Modelling the response of shallow groundwater levels to combined climate and water-diversion scenarios in Beijing-Tianjin-Hebei Plain, China

NASA Astrophysics Data System (ADS)

Li, Xue; Ye, Si-Yuan; Wei, Ai-Hua; Zhou, Peng-Peng; Wang, Li-Heng

2017-09-01

A three-dimensional groundwater flow model was implemented to quantify the temporal variation of shallow groundwater levels in response to combined climate and water-diversion scenarios over the next 40 years (2011-2050) in Beijing-Tianjin-Hebei (Jing-Jin-Ji) Plain, China. Groundwater plays a key role in the water supply, but the Jing-Jin-Ji Plain is facing a water crisis. Groundwater levels have declined continuously over the last five decades (1961-2010) due to extensive pumping and climate change, which has resulted in decreased recharge. The implementation of the South-to-North Water Diversion Project (SNWDP) will provide an opportunity to restore the groundwater resources. The response of groundwater levels to combined climate and water-diversion scenarios has been quantified using a groundwater flow model. The impacts of climate change were based on the World Climate Research Programme's (WCRP's) Coupled Model Intercomparison Project phase 3 (CMIP3) multi-model dataset for future high (A2), medium (A1B), and low (B1) greenhouse gas scenarios; precipitation data from CMIP3 were applied in the model. The results show that climate change will slow the rate of decrease of the shallow groundwater levels under three climate-change scenarios over the next 40 years compared to the baseline scenario; however, the shallow groundwater levels will rise significantly (maximum of 6.71 m) when considering scenarios that combine climate change and restrictions on groundwater exploitation. Restrictions on groundwater exploitation for water resource management are imperative to control the decline of levels in the Jing-Jin-Ji area.

Conversations with Leaders: Principles of Effective Writing Instruction

ERIC Educational Resources Information Center

Zumbrunn, Sharon; Krause, Keegan

2012-01-01

Findings from research demonstrate that student writing proficiency and classroom writing instruction is a national concern (Applebee & Langer, 2006, 2009; Graham, Harris, Fink-Chorzempa, & MacArthur, 2003; Persky, Daane, & Jin, 2003). This qualitative study explored principles of effective writing instruction through the perspectives of leading…

75 FR 3467 - Ocean Transportation Intermediary License; Applicants

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-21

.../Secretary/ Treasurer. (Qualifying Individual) EB Logistics, LLC, 300 Colonial Center Parkway, Suite 100.... (Qualifying Individual) Tri-Vi-U.S. Logistics Ltd., 147-35 Farmers Blvd., Jamaica, NY 11434, Officers: Yehudit... Logistics LLC, 6 Emerald Court, Princeton Junction, NJ 08550, Yongpeng Jin, Owner. Officer: (Qualifying...

MICROWAVE-ASSISTED PREPARATION OF CYCLIC UREAS FROM DIAMINES

EPA Science Inventory

Rajender S. Varma* and Yong-Jin Kim
Cyclic ureas are useful intermediates for a variety of pharmaceuticals and pesticides. One of the attractive approaches for the synthesis of cyclic ureas uses condensation of diamines with urea as a carbonyl source under dynamic evacuation. ...

Computation and Theory in Large-Scale Optimization

DTIC Science & Technology

1993-01-13

Sang Jin Lee. Research Assistant. - Laura Morley, Research Assistant. - Yonca A. Ozge , Research Assistant. - Stephen M. Robinson. Professor. - Hichem...other participants. M.N. Azadez. S.J. Lee. Y.A. Ozge . and H. Sellami are continuing students in the doctoral program (in Industrial Engineering except

Development of a High Resolution-High Sensitivity Ion Microprobe Facility for Cosmochemical Applications

NASA Technical Reports Server (NTRS)

McKeegan, Kevin D.

1998-01-01

NASA NAGW-4112 has supported development of the CAMECA ims 1270 ion microprobe at UCLA for applications in cosmochemistry. The instrument has been brought to an operational status and techniques developed for accurate, precise microbeam analysis of oxygen isotope ratios in polished thin-sections. We made the first oxygen isotopic (delta(18)O and delta(17)O) measurements of rare mafic silicates in the most chemically primitive meteorites, the a chondrites (Leshin et al., 1997). The results have implications for both high temperature processing in the nebula and low-T aqueous alteration on the CI asteroid. We have performed measurements of oxygen isotopic compositions of magnetite and co-existing olivine from carbonaceous (Choi et al., 1997) and unequilibrated ordinary chondrites (Choi et al., in press). This work has identified a significant new oxygen isotope reservoir in the early solar system: water characterized by a very high Delta(17)) value of approx. 5 % per thousand. We have determined the spatial distributions of oxygen isotopic anomalies in all major mineral phases of a type B CAI from Allende. We have also studied an unusual fractionated CAI from Leoville and made the first oxygen isotopic measurements in rare CAIs from ordinary chondrites.

EDITORIAL: Flexible OLEDs and organic electronics Flexible OLEDs and organic electronics

NASA Astrophysics Data System (ADS)

Kim, Jang-Joo; Han, Min-Koo; Noh, Yong-Young

2011-03-01

-voltage, solution-processed organic field-effect transistors M Caironi, Y-Y Noh and H Sirringhaus Nonvolatile memory thin-film transistors using an organic ferroelectric gate insulator and an oxide semiconducting channel Sung-Min Yoon, Shinhyuk Yang, Chun-Won Byun, Soon-Won Jung, Min-Ki Ryu, Sang-Hee Ko Park, ByeongHoon Kim, Himchan Oh, Chi-Sun Hwang and Byoung-Gon Yu The status and perspectives of metal oxide thin-film transistors for active matrix flexible displays Jae Kyeong Jeong Vertical phase segregation of hybrid poly(3-hexylthiophene) and fullerene derivative composites controlled via velocity of solvent drying Tao Song, Zhongwei Wu, Yingfen Tu, Yizheng Jin and Baoquan Sun Variations of cell performance in ITO-free organic solar cells with increasing cell areas Jun-Seok Yeo, Jin-Mun Yun, Seok-Soon Kim, Dong-Yu Kim, Junkyung Kim and Seok-In Na

Analysis and Design of Manycore Processor-to-DRAM Opto-Electrical Networks with Integrated Silicon Photonics

DTIC Science & Technology

2009-12-24

Networks Silicon-Photonic Clos Networks for Global On-Chip Communication Ajay Joshi* Christopher Batten? Yong-Jin Kwon! Scott Beamer! Imran Shamim ...4th edition, 2007. •A\\ [13] A Joshi, C Batten, Y Kwon, S Beamer, Imran Shamim , Krste Asanovic, and Vladimir Sto- janovic. Silicon-photonic clos

Diagnostic Accuracy of Traditional Measures of Phonological Ability for Bilingual Preschoolers and Kindergarteners

ERIC Educational Resources Information Center

Fabiano-Smith, Leah; Hoffman, Katherine

2018-01-01

Purpose: Bilingual children whose phonological skills are evaluated using measures designed for monolingual English speakers are at risk for misdiagnosis of speech sound disorders (De Lamo White & Jin, 2011). Method: Forty-four children participated in this study: 15 typically developing monolingual English speakers, 7 monolingual English…

Physico-chemical and antioxidant properties of four mango (Mangifera indica L.) cultivars in China.

PubMed

Liu, Feng-Xia; Fu, Shu-Fang; Bi, Xiu-Fang; Chen, Fang; Liao, Xiao-Jun; Hu, Xiao-Song; Wu, Ji-Hong

2013-05-01

Four principal mango cultivars (Tainong No.1, Irwin, JinHwang and Keitt) grown in southern China were selected, and their physico-chemical and antioxidant properties were characterized and compared. Of all the four cultivars, Tainong No.1 had highest content of total phenols, ρ-coumaric acid, sinapic acid, quercetin, titratable acidity, citric acid, malic acid, fructose, higher antioxidant activities (DPPH, FRAP) and L(*), lower pH, PPO activity and individual weight. Keitt mangoes showed significantly (p<0.05) higher contents of β-carotene, ρ-hydroxybenzoic acid, sucrose, total sugar, total soluble solid, catechin, succinic acid and higher PPO activity. JinHwang mangoes exhibited significantly (p<0.05) higher individual weight and PPO activity, but had lower content of total phenols, β-carotene and lower antioxidant activity. Principal component analysis (PCA) allowed the four mango cultivars to be differentiated clearly based on all these physico-chemical and antioxidant properties determined in the study. Copyright © 2012 Elsevier Ltd. All rights reserved.

First record of the spider genus Wolongia Zhu, Kim Song, 1997 from India with the description of a new species (Araneae, Tetragnathidae).

PubMed

Malamel, Jobi J; Nafin, Karunnappilli Shamsudheen; Sankaran, Pradeep M; Sebastian, Pothalil A

2018-04-09

Zhu et al. (1997) erected the tetragnathid genus Wolongia to accommodate Wolongia guoi Zhu, Kim Song, 1997 and Wolongia wangi Zhu, Kim Song, 1997 collected from the Sichuan and Shaanxi Provinces in China. In 2009, Ping et al. described Wolongia odontodes from the Gaoligong Mountains and remained with a nominal representation after the erection of the genus. This situation was somewhat rectified by Jin-long Wan Xian-jin Peng (2013) reporting seven new species from the Gaoligong Mountains (Yunnan Province, southwest China). The genus currently with ten nominal species; three are known only from females, while seven are from both sexes (World Spider Catalog 2017). During our survey in Pathiramanal Island we found an undescribed Wolongia species. This is one of the most diverse areas of the Kerala state of Southern India, situated in the Vembanad Lake, a Ramsar Convention (2013) site (wetland of international importance). In this paper, we describe this new species and provide the first report of Wolongia from India.

[The relationship between acupuncture-moxibustion theory of DOU Hanqing and Neo- Confucianism].

PubMed

Li, Baojin; Huang, Longxiang

2018-02-12

For the construction factors of acupuncture-moxibustion theory of DOU Hanqing , a doctor in Jin-Yuan Dynasty, we studied his life, acupuncture-moxibustion theory and culture background in the History of Medicine and Philosophy of Science & Technology. It was found that the major source of DOU Hanqing ' s Confucianism was the CHENG - ZHU Neo-Confucianism. The data show that Neo-Confucianism played an important role in the enrichment of his human nature, spirit, moral cultivation and political talent, making him a scholar in the Jin - Yuan dynasty, also shaping his medical ethics, medical skill and acupuncture-moxibustion theory. The inheritance, development and application of CHENG - ZHU Neo-Confucianism provided the most fundamental thinking, research methods and patterns for DOU Hanqing to interpret the acupuncture classics, summarize his teachers' experience and develop his theoretical system. DOU Hanqing ' s acupuncture-moxibustion practice and theory reached a new level, because he took acupuncture-moxibustion as one of the knowledge investigation and attainment of CHENG - ZHU Neo-Confucianism.

Robust numerical simulation of porosity evolution in chemical vapor infiltration III: three space dimension

NASA Astrophysics Data System (ADS)

Jin, Shi; Wang, Xuelei

2003-04-01

Chemical vapor infiltration (CVI) process is an important technology to fabricate ceramic matrix composites (CMC's). In this paper, a three-dimension numerical model is presented to describe pore microstructure evolution during the CVI process. We extend the two-dimension model proposed in [S. Jin, X.L. Wang, T.L. Starr, J. Mater. Res. 14 (1999) 3829; S. Jin. X.L. Wang, T.L. Starr, X.F. Chen, J. Comp. Phys. 162 (2000) 467], where the fiber surface is modeled as an evolving interface, to the three space dimension. The 3D method keeps all the virtue of the 2D model: robust numerical capturing of topological changes of the interface such as the merging, and fast detection of the inaccessible pores. For models in the kinetic limit, where the moving speed of the interface is constant, some numerical examples are presented to show that this three-dimension model will effectively track the change of porosity, close-off time, location and shape of all pores.

Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place. Part 3 (Ashley Steel Inc-Bettencourt R E Inc)

DTIC Science & Technology

1990-01-01

Jin -JIn -j In -j In -1 O -. 100 -. 1000 I,. Hf - M (-4 Hic -.1JC ~In -JO0 . JCI -J in -.i n .1(1 -i in -JO0 . .04 .J044C C)~ 11(0M-4 ’wCD w LC W0...co 10.oc *< < 04-. <g < 4 4c 4( < � in- inIB- N N NNNNNNN con 004Co 100 * I0-4C)0B00 0 000 00 0-0 00 C00000C000 0 *I-4 Cl0 0c 0 000 0 0. 0...oI 011 0JN 0 r- r- -. 0cI 00 0.4 0 " NNN C S S N CYINSC4 04 NS C4 - M 0-4"ə L- a WjIn .. (D(0(0 CC4 >.N XN ( -000000 0 -N 1 100 -4N4 lUli < tg N -4C

A New Approach in Time-Frequency Analysis with Applications to Experimental High Range Resolution Radar Data

DTIC Science & Technology

2003-11-01

Distributions In contrast to the linear time-frequency transforms such as the short-time Fourier transform, the Wigner - Ville distribution ( WVD ) is...23 9 Results of nine TFDs: (a) Wigner - Ville distribution , (b) Born-Jordan distribution , (c) Choi-Williams distribution , (d) bilinear TFD...are applied in the Wigner - Ville class of time-frequency transforms and the reassignment methods, which are applied to any time-frequency distribution

Mid-frequency Environmental and Acoustic Studies From SW06, and Applications to Asian Littoral Waters

DTIC Science & Technology

2008-09-30

Research Laboratory, the Korean Agency for Defense Development (ADD), Hanyang University ( HYU ), to undertake collaborative research programs in...objective was to participate in experiment off the coast of Korea with NRL, ADD and HYU that occurred in August. APPROACH The main item of...directions with respect to the MORAY. Key individuals involved in SW06 data analysis include Jeewoong Choi ( HYU ) in relation to propagation analysis

Enhanced Soft Tissue Attachment and Fixation Using a Mechanically-Stimulated Cytoselective Tissue-Specific ECM Coating

DTIC Science & Technology

2013-01-01

of stimulation parameters . The deposited ECM was quantified. It was observed that the entirely strained stretching regime produced slightly higher... parameters (such as, % strain, strain duration, number of cycles, lag between cycles, etc.) that were commonly reported in the literature. There are many... hydroxyapatite . Biomaterials 2007;28(3):383-92. 18. Johnson GA, Tramaglini DM, Levine RE, Ohno K, Choi NY, Woo SL. Tensile and viscoelastic

Flexible Supercapacitors Based on Carbon Nanomaterials

DTIC Science & Technology

2014-02-26

Pasta , F. L. Mantia, L. Cui, S. Jeong, H. D. Deshazer, J. W. Choi, S. M. Han and Y. Cui, Nano Lett., 2010, 10, 708–714. J. Mater. Chem. A This...Liu, Y. Yang, H. Wu, Y. Yao, M. Pasta , H. N. Alshareef and Y. Cui, ACS Nano, 2011, 5, 8904–8913. 64 G. Yu, X. Xie, L. Pan, Z. Bao and Y. Cui, Nano

The Navy’s Superior Supplier Incentive Program: Analysis of Supplier Proposed Benefits

DTIC Science & Technology

2015-12-01

rather than “short-term, easy, expendable and replaceable sources of goods and services” (Carter & Choi, 2008, p. 2). Japanese automakers Toyota ...was the key element behind Toyota and Honda’s strategic successes. Under the supplier keiretsu, the automakers worked closely with the selected...suppliers to achieve mutually beneficial objectives. Toyota and Honda implemented the keiretsu model in their North American plants and achieved

Spectroscopic Characterization of Microplasmas

DTIC Science & Technology

2009-09-20

Symposium on Plasma Chemistry (Bochum, Germany, Jul. 2009). 22. K. Tachibana: “Microplasma Generation in Artificial Media and its Potential Applications...Plenary)”, 19th International Symposium on Plasma Chemistry (Bochum, Germany, Jul. 2009). - 18 - 23. K. Urabe, J. Choi, Y. Ito, K. Tachibana and... Plasma Chemistry (Bochum, Germany, Jul. 2009). 24. T. Morita, O. Sakai, T. Shirafuji and K. Tachibana: “Underwater Chemical Reactions by

The Situation Awareness Weighted Network (SAWN) Model

DTIC Science & Technology

2014-06-01

Administration Task Load Index (NASA- TLX ), a validated research instrument [Human Performance Research Group 1988]. The participants were asked to rate their...analysis”, Human Factors 40(2): 254–276. 17 Human Performance Research Group (1988) NASA- TLX , NASA Ames Research Center, Moffett Field, CA. Jin, Y. and

Children in Detention and Shelter Care: Surveying the System in New Jersey.

ERIC Educational Resources Information Center

Wood, Linda J.; And Others

The report examines the characteristics of children (primarily between the ages of 6 and 17 years) placed in 42 New Jersey detention facilities, juveniles in need of supervision (JINS) shelters, and children's shelters; and provides descriptive information and analysis on the programs, policies, and budgets of these "temporary"…

The insect SNMP gene family

USDA-ARS?s Scientific Manuscript database

SNMPs are membrane proteins that have been shown to associate with chemosensory neurons in insects; in Drosophila melanogaster, SNMP1 has been shown to be essential for the detection of the pheromone cis vaccenyl acetate (Benton et al., 2001; Jin et al., 2008). To extend these observations to other ...

Leaf Morphological Characters Can Be a Factor for Intra-Varietal Preference of Whitefly Bemisia tabaci (Hemiptera: Aleyrodidae) among Eggplant Varieties.

PubMed

Hasanuzzaman, Abu Tayeb Mohammad; Islam, Md Nazrul; Zhang, Yi; Zhang, Chen-Yang; Liu, Tong-Xian

2016-01-01

The sweetpotato whitefly, Bemisia tabaci (Hemiptera: Aleyrodidae) MEAM1, is considered a serious pest of horticultural and many other crops. While eggplant (Solanum melongena) is one of the most favored host plants, the whiteflies exhibit preferences among different varieties. We hypothesized that certain morphological leaf characteristics of different varieties, like leaf trichome density, trichome length, leaf lamina thickness and leaf color, may affect whitefly landing, feeding and oviposition. In this study, we investigated the variation in leaf morphological characters among selected eggplant varieties and evaluated the effect of these leaf characteristics in rendering eggplant varieties either susceptible or resistant to B. tabaci. We evaluated eight eggplant varieties in choice feeding tests, and we found that the varieties JinSheng Zilongchangqie (JSZ) and H149 were the highly preferred varieties with the highest numbers of whitefly adults and eggs. Significantly lower numbers of whitefly adult eggs were found on the resistant variety Tuo Lu Bamu (TLB). The varieties JinGuangbo Luqie (JGL), JinGuangbo Ziquanqie (JGZ), DaYang Ziguanqie (DYZ), QinXing Ziguanqie (QXZ), and QinXing Niuxinqie (QXN) were moderately favored by B. tabaci. Leaf trichome density, trichome length and leaf lamina thickness were positively correlated with numbers of whitefly adults and eggs. B. tabaci was less attracted to the leaves that reflect long and middle wavelength light (higher R and G values) than to the bright green leaves (medium G value), but the short wavelength light (higher B value) had no significant effect on whitefly preference. The degree of hue had a positive effect, and saturation and brightness had a negative effect on whitefly attraction.

Impact Evaluation of the National Writing Project's College-Ready Writing Project in High Poverty Rural Districts

ERIC Educational Resources Information Center

Gallagher, H. Alix; Arshan, Nicole; Woodworth, Katrina

2016-01-01

Writing is an essential skill for participating in modern American society. Although it is crucial to careers and civic engagement, student writing falls far short of national expectations (College Board, 2004; NCES, 2012; Persky, Daane, & Jin, 2003). The Common Core State Standards (CCSS) seek to increase the rigor of writing instruction…

Perspectives of Chinese American Education in the 21st Century. Proceedings of the Annual International Conference of the Chinese American Research and Development Association (CAERDA) (5th, Houston, Texas, September 20, 1997).

ERIC Educational Resources Information Center

Chinese American Educational Research and Development Association, Rockville, MD.

The papers from this conference are presented in three parts. Part 1 includes the panel sessions. Section 1 of part 1, "Trends, Policies, and Resources in Education," includes the following papers: "Continuing Higher Education and the Asian-American Perspective" (L.L. Hsu); "New Directions for Education: Minister Jin Wu's…

Computer-Based English Language Testing in China: Present and Future

ERIC Educational Resources Information Center

Yu, Guoxing; Zhang, Jing

2017-01-01

In this special issue on high-stakes English language testing in China, the two articles on computer-based testing (Jin & Yan; He & Min) highlight a number of consistent, ongoing challenges and concerns in the development and implementation of the nationwide IB-CET (Internet Based College English Test) and institutional computer-adaptive…

Assessing Threat Detection Scenarios through Hypothesis Generation and Testing

DTIC Science & Technology

2015-12-01

task of playing chess with that of diagnosing medical conditions. Whereas both chess players and physicians must recognize patterns among a fixed...additional cues, all while maintaining these details in memory. Thus, the common research finding that chess experts can hold and process more information...of General Psychology, 124, 19-34. Chase, W. G., & Simon, H. A. (1973). Perception in chess . Cognitive Psychology, 4, 55-81. Choi, E., & Lee

GABAA Receptor-Mediated Activity in a Model of Cortical Dysplasia

DTIC Science & Technology

2012-06-29

epilepsy, autism and schizophrenia, and results from failure of immature neurons to appropriately migrate to their cortical targets. We developed a...schizophrenia, and autism , and results from failure of immature neurons to appropriately migrate and reach their cortical targets (Taylor et al., 1971; Choi and...2012) autism (Fatemi et al., 2006 , 2009; Chao et al., 2010; Oblak et al., 2010; Chattopaddhyaya and Di Cristo, 2012; Kang and Barnes; 2012), and X

Predictive Coding Strategies for Invariant Object Recognition and Volitional Motion Control in Neuromorphic Agents

DTIC Science & Technology

2015-09-02

human behavior. In this project, we hypothesized that visual memory of past motion trajectories may be used for selecting future behavior. In other...34Decoding sequence of actions using fMRI ", Society for Neuroscience Annual Meeting, San Diego, CA, USA, Nov 9-13 2013 (only abstract) 3. Hansol Choi, Dae...Shik Kim, "Planning as inference in a Hierarchical Predictive Memory ", Proceedings of International Conference on Neural Information Processing

Jak/STAT Inhibition to Prevent Post-Traumatic Epileptogenesis

DTIC Science & Technology

2012-07-01

display different cellular responses n status epilepticus models (Schauwecker and Steward, 1997), nd/or are often used in transgenic studies. Severe brain...after status epilepticus (SE). This study investigated changes in these pathways after experimental TBI in the rat using a lateral fluid percussion... status epilepticus (SE) (Choi et al., 2003, Lund et al., 2008). Following SE, the JaK/STAT pathway has been shown to regulate the γ-aminobutyric acid

Potential Science and Technology Game Changers for the Ground Warfare of 2050: Selected Projections Made in 2017

DTIC Science & Technology

2018-02-01

ARL-TR-8283 ● FEB 2018 US Army Research Laboratory Potential Science and Technology Game Changers for the Ground Warfare of 2050...report when it is no longer needed. Do not return it to the originator. ARL-TR-8283 ● FEB 2018 US Army Research Laboratory Potential...ARL Kwong Choi and Joseph Mait Sensors and Electron Devices Directorate, ARL Brad Forch and Shashi Karna Weapons and Materials Research

Time-Frequency Signal Representations Using Interpolations in Joint-Variable Domains

DTIC Science & Technology

2016-06-14

distribution kernels,” IEEE Trans. Signal Process., vol. 42, no. 5, pp. 1156–1165, May 1994. [25] G. S. Cunningham and W. J. Williams , “Kernel...interpolated data. For comparison, we include sparse reconstruction and WVD and Choi– Williams distribution (CWD) [23], which are directly applied to...Prentice-Hall, 1995. [23] H. I. Choi and W. J. Williams , “Improved time-frequency representa- tion of multicomponent signals using exponential kernels

Quasiperiodic Strain Bursts and Self-Organization in Crystal Microplasticity (PREPRINT)

DTIC Science & Technology

2012-03-01

AFRL-RX-WP-TP-2012-0249 QUASIPERIODIC STRAIN BURSTS AND SELF- ORGANIZATION IN CRYSTAL MICROPLASTICITY (PREPRINT) D.M. Dimiduk Metals...2012 4. TITLE AND SUBTITLE QUASIPERIODIC STRAIN BURSTS AND SELF-ORGANIZATION IN CRYSTAL MICROPLASTICITY (PREPRINT) 5a. CONTRACT NUMBER In-house...18 Quasiperiodic strain bursts and self-organization in crystal microplasticity S. Papanikolaou,1,2∗ D. M. Dimiduk,3 W. Choi4, J. P. Sethna4, M. D

Effects of Anthropometrics and Body Size Changes on the Development of Personal Protective Equipment (PPE) Sizing Systems in the US Army

DTIC Science & Technology

2016-08-01

ANTHROPOMETRICS AND BODY SIZE CHANGES ON THE DEVELOPMENT OF PERSONAL PROTECTIVE EQUIPMENT (PPE) SIZING SYSTEMS IN THE US ARMY by Hyeg Joo Choi* Todd...EFFECTS OF ANTHROPOMETRICS AND BODY SIZE CHANGES ON THE DEVELOPMENT OF PERSONAL PROTECTIVE EQUIPMENT (PPE) SIZING SYSTEMS IN THE US ARMY 5a. CONTRACT...Universities (ORAU) Maryland, 4692 Millennium Drive, Suite 101, Belcamp, MD 21017 14. ABSTRACT Understanding body size and shape information of military

Band-to-Band Tunnel Transistor Design and Modeling for Low Power Applications

DTIC Science & Technology

2012-05-10

suggestions for reducing this burden, to Washington Headquarters Services , Directorate for Information Operations and Reports, 1215 Jefferson Davis Highway...Fabrication 4.3 Analysis of the Silicided Source TFET 4.4 Subthreshold Swing Data Quality Analysis 4.5 Selective Silicide Using Germanium 4.6... International Electron Devices Meeting (IEDM) Short Course, 2007 [1.3] W. Y. Choi, B.-K. Park, J. D. Lee, and T.-J. King Liu, “Tunneling Field-Effect

Criminal Sovereignty: Understanding North Korea’s Illicit International Activities

DTIC Science & Technology

2010-03-01

Kwang-min, “The Political Economy of the North Korean Famine,” Seoul, Korea: Sidae Jungsin Publishers, 2005 (in Korean). 61. Kim Kwang-jin, “The...National Economy,” Sidae Jungsin Journal, Summer 2008 (in Korean), available from www.sdjs.co.kr. 67. Ibid. 68. See Jack Kim, “North Korea leader

Nicholas Gilroy | NREL

Science.gov Websites

Nicholas Gilroy desc Nicholas Gilroy Geospatial Data Scientist II Nicholas.Gilroy@nrel.gov | 303 -384-7354 Nicholas Gilroy is a member of the Geospatial Data Science team within the Systems Modeling (AAG) Featured Publications Veda, Santosh, Zhang, Yingchen, Tan, Jin, Chartan, Erol Kevin, Gilroy

Cultural Foundations of Learning: East and West

ERIC Educational Resources Information Center

Li, Jin

2012-01-01

Western and East Asian people hold fundamentally different beliefs about learning that influence how they approach child rearing and education. Reviewing decades of research, Dr. Jin Li presents an important conceptual distinction between the Western mind model and the East Asian virtue model of learning. The former aims to cultivate the mind to…

Korean Heritage Language Education in the United States: The Current State, Opportunities, and Possibilities

ERIC Educational Resources Information Center

Lee, Jin Sook; Shin, Sarah J.

2008-01-01

The idea for this special issue of the "Heritage Language Journal" on Korean grew out of a symposium on "Bilingualism and Biculturalism in the Korean American Community" at the 2005 International Association of Applied Linguistics (AILA) conference in Wisconsin, Madison organized by Jin Sook Lee and Adrienne Lo. The broad participation and…

Hypothesis Testing of Edge Organizations: Laboratory Experimentation Using the ELICIT Multiplayer Intelligence Game

DTIC Science & Technology

2007-06-01

Sea: Naval Command and Control since the Sixteenth Century. Cambridge, MA: Harvard University Press, 2005, pp. 400. [22] R. M. Leighton , "Allied...Information Processing View," Interfaces, vol. 4, pp. 28-36, May. 1974. [84] R. E. Levitt, J. Thomsen, T. R. Christiansen , J. C. Kunz, Y. Jin and C. I

The Need of Safety-Net Programme for a Mass Education System

ERIC Educational Resources Information Center

Wong, Edwin K. P.; Ngai, Sze Wan Emily; Lo, King Shuen

2006-01-01

Background: The Project Yi Jin (PYJ), an alternative pathway for secondary school leavers and adults to further their education, has been receiving full support from the government, the Federation for Continuing Education in Tertiary Institutions (FCE) in Hong Kong and the public. Graduates of PYJ have the equivalent academic status of their…

Research Training Program in Breast Cancer

DTIC Science & Technology

2000-07-01

fluorescence microscopy. 623-628, 1999. Cons•ruction of p190-B Expression Vector. The expression plasnmid 4. Thordarson , G., Jin, E., Guzman, R. C...10 Mg/ml), epidermal growth factor (20ng/ml), cholera toxin 10. Guzman, R. C., Yang, J., Ralkumar, L., Thordarson , G., Chen, X., and (1 00ng/mI

Novel Aeruginosin-865 from Nostoc sp. as a potent anti-inflammatory agent.

PubMed

Kapuścik, Aleksandra; Hrouzek, Pavel; Kuzma, Marek; Bártová, Simona; Novák, Petr; Jokela, Jouni; Pflüger, Maren; Eger, Andreas; Hundsberger, Harald; Kopecký, Jiří

2013-11-25

Aeruginosin-865 (Aer-865), isolated from terrestrial cyanobacterium Nostoc sp. Lukešová 30/93, is the first aeruginosin-type peptide containing both a fatty acid and a carbohydrate moiety, and is the first aeruginosin to be found in the genus Nostoc. Mass spectrometry, chemical and spectroscopic analysis as well as one- and two-dimensional NMR and chiral HPLC analysis of Marfey derivatives were applied to determine the peptidic sequence: D-Hpla, D-Leu, 5-OH-Choi, Agma, with hexanoic and mannopyranosyl uronic acid moieties linked to Choi. We used an AlphaLISA assay to measure the levels of proinflammatory mediators IL-8 and ICAM-1 in hTNF-α-stimulated HLMVECs. Aer-865 showed significant reduction of both: with EC50 values of (3.5±1.5) μg mL(-1) ((4.0±1.7) μM) and (50.0±13.4) μg mL(-1) ((57.8±15.5) μM), respectively. Confocal laser scanning microscopy revealed that the anti-inflammatory effect of Aer-865 was directly associated with inhibition of NF-κB translocation to the nucleus. Moreover, Aer-865 did not show any cytotoxic effect. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

High-Resolution Infrared Spectroscopy of Imidazole Clusters in Helium Droplets Using Quantum Cascade Lasers

NASA Astrophysics Data System (ADS)

Mani, Devendra; Can, Cihad; Pal, Nitish; Schwaab, Gerhard; Havenith, Martina

2017-06-01

Imidazole ring is a part of many biologically important molecules and drugs. Imidazole monomer, dimer and its complexes with water have earlier been studied using infrared spectroscopy in helium droplets^{1,2} and molecular beams^{3}. These studies were focussed on the N-H and O-H stretch regions, covering the spectral region of 3200-3800 \\wn. We have extended the studies on imidazole clusters into the ring vibration region. The imidazole clusters were isolated in helium droplets and were probed using a combination of infrared spectroscopy and mass spectrometry. The spectra in the region of 1000-1100 \\wn and 1300-1460 \\wn were recorded using quantum cascade lasers. Some of the observed bands could be assigned to imidazole monomer and higher order imidazole clusters, using pickup curve analysis and ab initio calculations. Work is still in progress. The results will be discussed in detail in the talk. References: 1) M.Y. Choi and R.E. Miller, J. Phys. Chem. A, 110, 9344 (2006). 2) M.Y. Choi and R.E. Miller, Chem. Phys. Lett., 477, 276 (2009). 3) J. Zischang, J. J. Lee and M. Suhm, J. Chem. Phys., 135, 061102 (2011). Note: This work was supported by the Cluster of Excellence RESOLV (Ruhr-Universitat EXC1069) funded by the Deutsche Forschungsgemeinschaft.

[Spatial temporal differentiation of product-based and consumption-based CO2 emissions and balance in the Beijing-Tianjin-Hebei region: an economic input- output analysis].

PubMed

Wang, Hao; Chen, Cao-cao; Pan, Tao; Liu, Chun-lan; Chen, Long; Sun, Li

2014-09-01

Distinguishing product-based and consumption-based CO2 emissions in the open economic region is the basis for differentiating the emission responsibility, which is attracting increasing attention of decision-makers'attention. The spatial and temporal characteristics of product-based and consumption-based CO2 emissions, as well as carbon balance, in 1997, 2002 and 2007 of JING- JIN-JI region were analyzed by the Economic Input-Output-Life Cycle Assessment model. The results revealed that both the product- based and consumption-based CO2 emissions in the region have been increased by about 4% annually. The percentage of CO2 emissions embodied in trade was 30% -83% , to which the domestic trading added the most. The territorial and consumption-based CO2 emissions in Hebei province were the predominant emission in JING-JIN-JI region, and the increasing speed and emission intensity were stronger than those of Beijing and Tianjin. JING-JIN-JI region was a net inflow region of CO2 emissions, and parts of the emission responsibility were transferred. Beijing and Tianjin were the net importers of CO2 emissions, and Hebei was a net outflow area of CO2 emissions. The key CO2 emission departments in the region were concentrated, and the similarity was great. The inter-regional mechanisms could be set up for joint prevention and control work. - Production and distribution of electricity, gas and water and smelting and pressing of metals had the highest reliability on CO2 emissions, and took on the responsibility of other departments. The EIO-LCA model could be used to analyze the product-based and consumption-based CO2 emissions, which is helpful for the delicate management of regional CO2 emissions reduction and policies making, and stimulating the reduction cooperation at regional scale.

Causative impact of air pollution on evapotranspiration in the North China Plain.

PubMed

Yao, Ling

2017-10-01

Atmospheric dispersion conditions strongly impact air pollution under identical surface emissions. The degree of air pollution in the Jing-Jin-Ji region is so severe that it may impose feedback on local climate. Reference evapotranspiration (ET 0 ) plays a significant role in the estimation of crop water requirements, as well as in studies on climate variation and change. Since the traditional correlation analysis cannot capture the causality, we apply the convergent cross mapping method (CCM) in this study to observationally investigate whether the air pollution impacts ET 0 . The results indicate that southwest regions of Jing-Jin-Ji always suffer higher PM 2.5 concentration than north regions through the whole year, and correlation analysis suggests that PM 2.5 concentration has a significant negative effect on ET 0 in most cities. The causality detection with CCM quantitatively demonstrates the significantly causative influence of PM 2.5 concentration on ET 0 , higher PM 2.5 concentration decreasing ET 0 . However, CCM analysis suggests that PM 2.5 concentration has a relatively weak causal influence on ET 0 while the correlation analysis gives the near zero correlation coefficient in Zhangjiakou city, indicating that the causative influence of PM 2.5 concentration on ET 0 is better revealed with CCM method than the correlation analysis. Considering that ET 0 is strongly associated with crop water requirement, the amount of water for agricultural irrigation could be reduced at high PM 2.5 concentrations. These findings can be utilized to improve the efficiency of water resources utilization, and reduce the exploiting amount of groundwater in the Jing-Jin-Ji region, although PM 2.5 is detrimental to human health. Copyright © 2017 Elsevier Inc. All rights reserved.

77 FR 66084 - Quarterly Publication of Individuals, Who Have Chosen To Expatriate, as Required by Section 6039G

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-01

... purposes of this listing, long-term residents, as defined in section 877(e)(2), are treated as if they were... GABRIELLE APONTE ERICK ELVIS ARBENZ ULRICH CURT ARNET LISA SUSANNA ASFOUR CATHERINE ELIZABETH AUGUSTE-GRANT... DANIELLE NICOLE LAUTER- STEPHANIE E. BURG LEE AMY SOYOUNG LEE HIJUNG CHAI LEE HYUK JUN LEE HYUN WOO LEE JIN...

Instructional Practices: An Evaluation of a K4-8 School's Writing Program

ERIC Educational Resources Information Center

MacCudden, Renae Marie

2010-01-01

Teaching children to write successfully is an area of great concern to educators in the 21 st century. According to the National Assessment of Educational Progress (NAEP) data, the writing skills of two-thirds of the students in elementary, middle, and high school are below grade level proficiency (Persky, Daane, & Jin, 2003). In 2003, the…

Toxic Hazards Research Unit Annual Report: 1987

DTIC Science & Technology

1988-03-01

Low Density Lipoproteins and in Model Membranes 14 Sep Is Cigarette Smoking Neurotoric? Mr. Steven Goden Dr. R. Kutzman 4> ’October 1986 through September 1987 2I ...based pharmcokinetic model phosphoniteo,o-diethylmethyl quantitative structure activity relationship respiratory epithelium Salmonella sensitization j...in Cultured Respiratory Epithelial Cells ----------------------- ------------ 73 6 PHARMACOKINETIC AND PHARMACODYNAMIC MODELING .------------------ 78

Formation of Sphere-like Au Nanoparticles on Substrate with Laser Illumination and Their Surface Plasmon Behaviors

DTIC Science & Technology

2010-09-17

depends on the material type of the substrate and the metal melting temperature. Based on the reaction -free theory, the contact angle of an Au...Luo, Q.; Zhang, X. Nano Lett. 2004, 4, 1085-1088. (13) Maillard , M.; Huang, P.; Brus, L. Nano Lett. 2003, 3, 1611-1615. (14) Jin, R.; Cao, Y. C.; Hao

Primary and Secondary Superresolution by Data Inversion (Postprint)

DTIC Science & Technology

2005-06-06

4. H. Liu, Y. Yan, Q. Tan, and G. Jin, “Theories for the design of diffractive superresolution elements and limits of optical superresolution ,” J...optical system. This latter approach is often referred to as “ optical superresolution ” and is useful when a narrow pre-detection PSF is desired as is the

A Model of Trust, Moods, and Emotions in Multiagent Systems and its Empirical Evaluation

DTIC Science & Technology

2014-05-05

North Carolina State University 2701 Sullivan Drive Suite 240, Campus Bx 7514 Raleigh, NC 27695 -7003 1 ABSTRACT A Model of Trust, Moods, and Emotions...Chan 2Jin-Hee Cho 3Sibel Adalı 1Munindar P. Singh 1North Carolina State University, Raleigh, NC- 27695 , US 2US Army Research Lab, Adelphi, MD-20783

Development of Novel Nonagonist PPAR-Gamma Ligands for Lung Cancer Treatment

DTIC Science & Technology

2016-08-01

Affymetrix gene expression profiling. To get the purest representation of this gene set, we generated fibroblasts from the brown adipose tissue of mice... tissues . It has been shown that p53 plays an important role in metabolism and adipose tissue function, and this may be modulated by PPARγ expression as...presentations. Poster Presentation: Melin J. Khandekar, Alex S. Banks , Dina Laznik- Bogoslavski, James P. White, Jang H. Choi, Kwok-kin Wong, Ted

Unconventional Signal Processing Using the Cone Kernel Time-Frequency Representation.

DTIC Science & Technology

1992-10-30

Wigner - Ville distribution ( WVD ), the Choi- Williams distribution , and the cone kernel distribution were compared with the spectrograms. Results were...ambiguity function. Figures A-18(c) and (d) are the Wigner - Ville Distribution ( WVD ) and CK-TFR Doppler maps. In this noiseless case all three exhibit...kernel is the basis for the well known Wigner - Ville distribution . In A-9(2), the cone kernel defined by Zhao, Atlas and Marks [21 is described

Multifunctional Poly(2,5-benzimidazole)/Carbon Nanotube Composite Films

DTIC Science & Technology

2010-01-01

Multifunctional Poly(2,5- benzimidazole )/Carbon Nanotube Composite Films JI-YE KANG,1 SOO-MI EO,1 IN-YUP JEON,1 YEONG SUK CHOI,2 LOON-SENG TAN,3 JONG...molecular-weight poly(2,5- benzimidazole ) (ABPBI). ABPBI/carbon nanotube (CNT) compo- sites were prepared via in situ polymerization of the AB-monomer in the...polymerization; multiwalled carbon nanotube (MWCNT); nano- composites; poly(2,5- benzimidazole ); (ABPBI); polycondensa- tion; poly(phosphoric acid); single-walled

Two Dilemmas and Vicious Cycle of Confrontation on the Continuity of the Division of the Korean Peninsula

DTIC Science & Technology

2011-12-01

Secondly, the Kim Jong -Il regime’s concerns over the regime survival became a primary explanation of its behavior and policies. Behind these concerns...articles argue the Kim Jong -Il’s health and the succession issue are important variables of North Korean behavior today.19 This section attempts to...19 Jinwook Choi, “Why is North Korea so Aggressive? Kim Jong -Il’s Illness and North Korea’s Changing Governing Style,” Policy

Efficient Algorithms for Bayesian Network Parameter Learning from Incomplete Data

DTIC Science & Technology

2015-07-01

Efficient Algorithms for Bayesian Network Parameter Learning from Incomplete Data Guy Van den Broeck∗ and Karthika Mohan∗ and Arthur Choi and Adnan ...notwithstanding any other provision of law , no person shall be subject to a penalty for failing to comply with a collection of information if it does...Wasserman, L. (2011). All of Statistics. Springer Science & Business Media. Yaramakala, S., & Margaritis, D. (2005). Speculative markov blanket discovery for optimal feature selection. In Proceedings of ICDM.

Hybrid Molecule-Nanocrystal Photon Upconversion Across the Visible and Near-Infrared

DTIC Science & Technology

2015-07-10

applications in solar energy, biological imaging , and data storage. In this Letter, CdSe and PbSe semiconductor nanocrystals are combined with molecular...Goldschmidt, J. C. Absolute Upconversion Quantum Yield of β-NaYF4 Doped with Er3+ and External Quantum Efficiency of Upconverter Solar Cell Devices...C. Peak External Photocurrent Quantum Efficiency Exceeding 100% via MEG in a Quantum Dot Solar Cell . Science 2011, 334, 1530−1533. (37) Choi, J.-H

Time-frequency distributions for propulsion-system diagnostics

NASA Astrophysics Data System (ADS)

Griffin, Michael E.; Tulpule, Sharayu

1991-12-01

The Wigner distribution and its smoothed versions, i.e., Choi-Williams and Gaussian kernels, are evaluated for propulsion system diagnostics. The approach is intended for off-line kernel design by using the ambiguity domain to select the appropriate Gaussian kernel. The features produced by the Wigner distribution and its smoothed versions correlate remarkably well with documented failure indications. The selection of the kernel on the other hand is very subjective for our unstructured data.

Non-Markovianity of Gaussian Channels.

PubMed

Torre, G; Roga, W; Illuminati, F

2015-08-14

We introduce a necessary and sufficient criterion for the non-Markovianity of Gaussian quantum dynamical maps based on the violation of divisibility. The criterion is derived by defining a general vectorial representation of the covariance matrix which is then exploited to determine the condition for the complete positivity of partial maps associated with arbitrary time intervals. Such construction does not rely on the Choi-Jamiolkowski representation and does not require optimization over states.

International Conference on Numerical Ship Hydrodynamics (6th), Held in Iowa City, Iowa on 2-5 August 1993,

DTIC Science & Technology

1994-01-01

length scales mensional hydrofoil and tip vortex flow around a F circulation three dimensional hydrofoil. The simulated mean v molecular viscosity flow...Unstructured Grid for Free Surface Flow Simulations , by T. Hino, L. Martinelli, and A. Jameson 173 "A Semi-Implicit Semi-Lagrangian Finite Element Model...Haussling Solid-Fluid Juncture Boundary Layer and Wake with Waves, by J.E. Choi and F. Stern 215 Direct Numerical and Large-Eddy Simulations of Turbulent

TREC 2012 Microblog Track Experiments at Kobe University

DTIC Science & Technology

2012-11-01

query expansion method. References 1. Cao, G., Nie, J.Y., Gao, J ., Robertson, S.: Selecting good expansion terms for pseudo-relevance feedback. In...SIGIR. (2008) 243–250 2. Choi, J ., Croft, W.B.: Temporal models for microblogs. In: CIKM. (2012) 2491–2494 3. Cilibrasi, R.L., Vitanyi, P.M.B.: The...Combining recency and topic-dependent temporal variation for microblog search. In: ECIR. (2013) 14. Ounis, I., Macdonald, C., Lin, J ., Soboroff, I

Delivery of Nano-Tethered Therapies to Brain Metastases of Primary Breast Cancer Using a Cellular Trojan Horse

DTIC Science & Technology

2014-10-01

Delivery of nanoparticles to brain metastases of breast cancer using a cellular Trojan horse. Cancer Nanotechnol. 3, 47–54 (2012). 2. C. Qiao et...nn5002886. 8. H. Gao et al., Behavior and anti-glioma effect of lapatinib-incorporated lipoprotein-like nanoparticles . Nanotechnology . 23, 435101 (2012...948. [2] Mi-Ran Choi, et al., “Delivery of nanoparticles to brain metastases of breast cancer using a cellular Trojan horse”, Cancer Nano, 2012; 3

Mini-Tn7 Insertion in Bacteria With Multiple glmS-Linked attTn7 Sites: Example Burkholderia Mallei ATCC 23344

DTIC Science & Technology

2006-06-27

INTRODUCTION Burkholderia mallei is the etiological agent of glanders and a highly evolved obligate zoonotic mammalian pathogen that naturally affects horses...mini-Tn7 insertion in bacteria with multiple glmS-linked attTn7 sites: example Burkholderia mallei ATCC 23344 Kyoung-Hee Choi1, David DeShazer2... glanders is a rare disease, B. mallei has received renewed attention because of its listing as a category B agent by the Centers for Disease Control

Thermal-Polarimetric and Visible Data Collection for Face Recognition

DTIC Science & Technology

2016-09-01

pixels • Spectral range: 7.5–13 μm • Analog image output: NTSC analog video • Digital image output: Firewire radiometric, 14-bit digital video to...PC The analog video was not used for this study. The radiometric, 14-bit digital data provided temperature measurement information for comparison...distribution unlimited. 18 9. References 1. Choi J, Hu S, Young SS, Davis LS. Thermal to visible face recognition. Proc. SPIE 8371, Sensing

Solid State Research

DTIC Science & Technology

1989-03-07

different regions of a single wafer, making possible multiwavelength optical intercon- nect technology. 6. ANALOG DEVICE TECHNOLOGY Superconducting...Sedlacek DJ. Ehrlich Monolithic Integration of H.K.. Choi GaAs/AlGaAs LED and Si Driver J.P. Mattia Circuit G.W. Turner B-Y. Tsaur An In-Situ...Study of the UV Photo- chemistry of Adsorbed TiCl4 by FTIR Spectroscopy R.P. Purohit M. Rothschild DJ. Ehrlich 6176 Transport and Kinetics

Design Sensitivity Method for Sampling-Based RBDO with Fixed COV

DTIC Science & Technology

2015-04-29

contours of the input model at initial design d0 and RBDO optimum design dopt are shown. As the limit state functions are not linear and some input...Glasser, M. L., Moore, R. A., and Scott, T. C., 1990, "Evaluation of Classes of Definite Integrals Involving Elementary Functions via...Differentiation of Special Functions," Applicable Algebra in Engineering, Communication and Computing, 1(2), pp. 149-165. [25] Cho, H., Bae, S., Choi, K. K

Effects of Body Armor Fit on Marksmanship Performance

DTIC Science & Technology

2016-09-01

center target also used in the single target task. TPs fired one shot per target, following the order of target engagement. They repeated firing in...quickly TPs moved from one target to the next. TPs were allowed as much time for their first shot as needed and therefore, shot accuracy for the...FIT ON MARKSMANSHIP PERFORMANCE by Hyeg Joo Choi* K. Blake Mitchell Todd Garlie Jay McNamara Edward Hennessy and Jeremy Carson *Author

Identification and validation of vesicant therapeutic targets using a high, throughput siRNA screening approach

DTIC Science & Technology

2014-12-24

toxlet.2011.04.007 Rogers JV, Choi YW, Kiser RC et al (2004) Microarray analysis of gene expression in murine skin exposed to sulfur mustard. J Bio...Chemotactic factors released in culture by intact developing and healing skin lesions produced in rabbits by the irritant sulfur mustard. Inflam- mation 21(2...Project ID Number CBM.CUTOC.04.10. RC 00114. ABSTRACT See reprint. 15. SUBJECT TERMS sulfur mustard, cutaneous injury, siRNA, high-throughput screening

A Method to Predict the Reliability of Military Ground Vehicles Using High Performance Computing

DTIC Science & Technology

2006-11-01

Krayterman U.S. Army RDECOM-TARDEC Warren, MI 48397 K.K. Choi, Ed Hardee University of Iowa Coralville , IA 52242 Byeng D. Youn Michigan...University of Iowa , performed an optimization of the design for an A-arm on a military ground vehicle (a Stryker), using no sources of uncertainty...LSF for the queueing system. 3.3 Reliability/Fatigue Analysis software We used several pieces of propriety code from the University of Iowa

Manufacture of PCDE Prepolymer

DTIC Science & Technology

1977-10-01

Study ......... .......... 8 B. PBEP Process ................. .................. 10 I. Chemistry ....... ................. 10 2. Operating Conditions...DEPECH made therefrom for evaluation. Two mLthodb of iiproving the PECII were studied . The first method wis to subject "standard" PECH to treatment that...CH2 - CHO.I CI12 CHI2 OC(P 3 groups in this step. 2. Shell Development Study One of Tie objectives of Contract F04611-73-C-0051 was to improve the

The 3rd international conference on reproductive immunology in Shanghai: September 27-29, 2013. Shanghai, China.

PubMed

Du, MeiRong; Piao, HaiLan; Li, DaJin

2014-03-01

After the first and second international conferences on reproductive immunology held by Dr. DaJin Li in Shanghai, the related investigators all over the world hope to get together to share their latest findings with each other. Drs. DaJin Li and MeiRong Du sponsored and organized the third international conference on reproductive immunology at the Obstetrics and Gynecology Hospital affiliated with Fudan University, Shanghai, China, in the autumn of 2013. This congress brought together more than 100 International and National investigators representing a wide range of scientific disciplines. All the investigators actively work on reproductive immunology using human or large and small animal models. A range of reproductive immunological topics including the maternal-fetal immune regulation, reproductive tract mucosal immunology, immunocontraception, and pregnancy complications were highlighted and discussed in this conference. This conference supplied a good platform for the international reproductive immunologists to exchange their latest study progression and discuss the development direction of reproductive immunology in the near future. © 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Directory of Czechoslovak Officials; a Reference Aid

DTIC Science & Technology

1988-07-14

Jaroslav; KSS Barilla , Jan KSS Horvath, Stefan: A’SS Bartak, Stel’an KSS Horvathova, Marta: KSC Barton, Jaroslav Hricko, Peter: KSS Benyo, Matus: KSS...61 Bilek. Jin 78 Banarova. Eva is Bilek, /denck 4’) Barak, Ladislav 71 Biro~s, Branislav 10.40.41, Barilla , Jan .11 Bisko. fir,, Harlot’s, Paulina 6

Academics in Literature

ERIC Educational Resources Information Center

Stimpson, Catharine R.

2004-01-01

Academic literature has magnitude when it presents a character so robust that he or she takes off from the page and lands to nest in ordinary parlance. Three contrasting examples described in this article are: (1) "Moo," by Jane Smiley; (2) "The Human Stain," by Philip Roth; and (3) "The Crazed," by Ha Jin. Significantly, all three of these…

Travels With Pace - August 13-16, 2007 - U.S. Department of Defense

Science.gov Websites

Staff, and his South Korean counterpart Gen. Kim Kwan-Jin walk between an honor cordon of South Korean troops toward the Korean Ministry of Defense in Seoul, Korea, Aug. 16, 2007. Defense Dept. photo by Staff Sgt. D. Myles Cullen More photos Marine Gen. Peter Pace, chairman of the Joint Chiefs of Staff

Density Optimization of Lithium Lanthanum Titanate Ceramics for Lightweight Lithium-Air Batteries

DTIC Science & Technology

2014-11-01

Thangadurai V, Weppner W. Lithium lanthanum titanates: a review. Chemistry of Materials. 2003;15:3974–3990. 4. Knauth P. Inorganic solid Li ion conductors...an overview. Solid State Ionics. 2009;180:911–916. 5. Ban CW, Choi GM. The effect of sintering on the grain boundary conductivity of lithium ...lanthanum titanates. Solid State Ionics. 2001;140:285–292. 6. Inada R, Kimura K, Kusakabe K, Tojo T, Sakurai Y. Synthesis and lithium -ion conductivity

Thin Film Assembly of Spider Silk-like Block Copolymers

DTIC Science & Technology

2011-01-01

Shipley, N. H.; Lewis, R. V. Int. J. Biol.Macromol. 1999, 24, 271. (c) Thiel, B. L.; Guess, K. B.; Viney, C. Biopolymers 1997, 41, 703. (13) Silk ...Film Assembly of Spider Silk -like Block Copolymers Sreevidhya T. Krishnaji,†,‡ Wenwen Huang,§ Olena Rabotyagova,†,‡ Eugenia Kharlampieva, ) Ikjun Choi...Received November 26, 2010 We report the self-assembly of monolayers of spider silk -like block copolymers. Langmuir isotherms were obtained for a series of

Impact of Backbone Rigidity on the Photomechanical Response of Glassy, Azobenzene-Functionalized Polyimides (Postprint)

DTIC Science & Technology

2014-01-13

Y .; Choi, H . H .; Hwang , H . K.; Kim, Y .; Lee , S .; Jang, S . H .; Kakimoto, M.; Takezoe, H . Jpn. J. Appl. Phys., Part 1: Regul. Pap. Short Notes Rev... H .; Vaia, R. A.; Tan, L. S .; White, T. J. Angew. Chem., Int. Ed. 2012, 51 (17), 4117−4121. (6) Wang, D. H .; Lee , K. M.; Yu, Z. N .; Koerner, H .; Vaia...J. Macromol. Chem. Phys. 2013, 214 (11), 1189−1194. (8) Wang, D. H .; Lee , K. M.;

Pensions and Intertemporal Choice: Evidence from the U.S. Military

DTIC Science & Technology

2014-02-01

to rise to $116.9 billion by 2035 (Office of the Actuary , 2013). In response to these rising costs, the National Defense Authoriza- tion Act of 2000...Discount rates inferred from deci- sions: An experimental study,” Management science , 1989, 35 (3), 270–284. Beshears, John, James J Choi, David...1149–1187. Office of the Actuary , “Statistical Report on the Military Retirement System for Fiscal Year 2012,” US Department of Defense, 2013. Ruderman

Spring Research Festival and NICBR Collaboration Winners Announced | Poster

Cancer.gov

By Carolynne Keenan, Contributing Writer, and Ashley DeVine, Staff Writer The winners of the 2014 Spring Research Festival (SRF), held May 7 and 8, were recognized on July 2, and included 20 NCI at Frederick researchers: Matthew Anderson, Victor Ayala, Matt Bess, Cristina Bergamaschi, Charlotte Choi, Rami Doueiri, Laura Guasch Pamies, Diana Haines, Saadia Iftikhar, Maria Kaltcheva, Wojciech Kasprzak, Balamurugan Kuppusamy, James Lautenberger, George Lountos, Megan Mounts, Uma Mudunuri, Martha Sklavos, Gloriana Shelton, Alex Sorum, and Shea Wright.

North Adriatic Tides: Observations, Variational Data Assimilation Modeling, and Linear Tide Dynamics

DTIC Science & Technology

2009-12-01

of the North Adriatic ( Lee et al., 2005). In addition to the ADCP measurements of currents through- out the water column, bottom pressure (by ADCP or...of the year with low levels of stratification (Figure 2, Jeffries and Lee , 2007). Actual generation of internal tides in the North Adriatic would...Thompson, K.R., Teague, W. J., Jacobs, G.A., Suk, M.-S., Chang, K.-I., Lee , J.-C. and Choi, B.H. (2004): Data assimilation modeling of the barotropic

Sparsity Aware Adaptive Radar Sensor Imaging in Complex Scattering Environments

DTIC Science & Technology

2015-06-15

while meeting the requirement on the peak to average power ratio. Third, we study impact of waveform encoding on nonlinear electromagnetic tomographic...Enyue Lu. Time Domain Electromagnetic Tomography Using Propagation and Backpropagation Method, IEEE International Conference on Image Processing...Received Paper 3.00 4.00 Yuanwei Jin, Chengdon Dong, Enyue Lu. Waveform Encoding for Nonlinear Electromagnetic Tomographic Imaging, IEEE Global

The Case Survey and Alternative Methods for Research Aggregation

DTIC Science & Technology

1974-06-01

of FolLow-Through programs were found to predollinate Jin one set of pooled data with common statistical characteristics, aod studies of Montessori ...be mad compatible. l"’we" and other mundane d if f icu ties have a t renendous ca ac i tv to ctonsurW ’ i M- and energy. Montessori ), or they could be

A New Kind of Laser Microphone for Photoacoustic Applications

DTIC Science & Technology

2008-12-01

1 A NEW KIND OF LASER MICROPHONE FOR PHOTOACOUSTIC APPLICATIONS Chen-Chia Wang, Sudhir Trivedi, and Feng Jin Brimrose ...NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Brimrose Corp. of America, 7720 Belair Road...laser microphone’s performance are also developed with preliminary experimental validation. ACKONWLEDGMENTS The authors from Brimrose

Bayesian Aggregation of Evidence for Detection and Characterization of Patterns in Multiple Noisy Observations

DTIC Science & Technology

2015-07-01

undergraduate student coauthors Aashish Jindia, Parag Srivastava, and Jay Jin for help with the research. In addition, thank you to the numerous...103 A.1.1 Sacramento Data Set . . . . . . . . . . . . . . . . . . . . . . . . . . . . 104 A.1.2 RadMap and SUNS Data Sets...parameters in a joint hypothesis space. We develop scalable branch and bound and pruning mechanisms for searching (at multiple resolutions) over source

Systemic stereoselectivity study of flufiprole: Stereoselective bioactivity, acute toxicity and environmental fate.

PubMed

Tian, Mingming; Zhang, Qing; Hua, Xiude; Tang, Bowen; Gao, Beibei; Wang, Minghua

2016-12-15

In this study, the stereoselectivity of flufiprole enantiomers in regards to their bioactivity, acute toxicity and environmental fate is reported for the first time. Four types of representative insects (Plutella xylostella, Nilaparvata lugens, Mythimna separata and Acyrthosiphon pisum) were used to investigate enantioselective bioactivity. Acute toxicities of flufiprole enantiomers toward two non-target organisms were also evaluated. Moreover, stereoselective degradation in four vegetables under field conditions was studied in response to food safety concerns. The bioactivity of (R)-flufiprole was 1.9-5.1 times higher than that of (S)-flufiprole. (R)-flufiprole also showed 3.7-5.7 times higher acute toxicity to Scenedesmus obliquus and Trichogramma japonicum Ashmead than (S)-flufiprole. Opposite stereoselective degradation of the two enantiomers was observed in pak choi, spinach cucumber, and tomato. (S)-flufiprole degraded faster in pak choi and spinach, resulting in an enrichment of (R)-isomer. By contrast, (R)-isomer was preferentially degraded in cucumber and tomato. Molecular simulation technology was used to illuminate the mechanism of enantioselective bioactivity. The Glide Score (-5.82kcal/mol) for (R)-isomer was better than that (-5.11kcal/mol) of (S)-isomer and this calculation showed (R)-flufiprole was more effective in pest control. Consequently, significant stereoselectivity of flufiprole enantiomers should be taken into account when assessing the environmental health risk of the pesticide. Copyright © 2016 Elsevier B.V. All rights reserved.

Stability of Blowup for a 1D Model of Axisymmetric 3D Euler Equation

NASA Astrophysics Data System (ADS)

Do, Tam; Kiselev, Alexander; Xu, Xiaoqian

2016-10-01

The question of the global regularity versus finite- time blowup in solutions of the 3D incompressible Euler equation is a major open problem of modern applied analysis. In this paper, we study a class of one-dimensional models of the axisymmetric hyperbolic boundary blow-up scenario for the 3D Euler equation proposed by Hou and Luo (Multiscale Model Simul 12:1722-1776, 2014) based on extensive numerical simulations. These models generalize the 1D Hou-Luo model suggested in Hou and Luo Luo and Hou (2014), for which finite-time blowup has been established in Choi et al. (arXiv preprint. arXiv:1407.4776, 2014). The main new aspects of this work are twofold. First, we establish finite-time blowup for a model that is a closer approximation of the three-dimensional case than the original Hou-Luo model, in the sense that it contains relevant lower-order terms in the Biot-Savart law that have been discarded in Hou and Luo Choi et al. (2014). Secondly, we show that the blow-up mechanism is quite robust, by considering a broader family of models with the same main term as in the Hou-Luo model. Such blow-up stability result may be useful in further work on understanding the 3D hyperbolic blow-up scenario.

Incorporation of C-Kaurene into the Gibberellin of a Higher Plant (Pharbitis nil Chois).

PubMed

Barendse, G W; Kok, N J

1971-10-01

Enzymic formation of (14)C-kaurene from 2-(14)C-mevalonate was carried out with a cell-free system of Cucurbita pepo L. It was shown that either heating of the enzyme system or the addition of the growth retardants (2-chloroethyl)-trimethylammonium chloride and 2'-isopropyl-4' (trimethylammonium chloride)-5'-methylphenyl piperidine-1-carboxylate prevented the synthesis of (14)C-kaurene. Experiments in which (14)C-kaurene was applied to seedlings of Pharbitis nil revealed that the kaurene is converted to at least two compounds present in the acidic ethyl acetate fraction, containing free gibberellins, as well as in the second acidic ethyl acetate fraction, containing the released bound gibberellins. One of the compounds cochromatographed with gibberellic acid; the other compound is possibly a break-down product of gibberellic acid with no biological activity.

A Novel Member of the Insulin-Like Growth Factor Binding Protein Superfamily in Prostate Cancer

DTIC Science & Technology

2004-02-01

1269, 2002. The effect of sodium butyrate (NaB), a potent inhibitor of cancer cell growth, on the regulation of IGFBP-rP2 expression was correlated...4072-4080, 2000 3. Tsubaki J, Choi W-K, Ingermann AR, Twigg SM, Kim H-S, Rosenfeld RG, Oh Y: Effects of sodium butyrate on expression of members of...injected over the activated surface in a 10-mM sodium reproducibility. acetate solution. A solution of I m ethanolamine was then passed over the

Enhancing the Immune Response to Recombinant Plague Antigens

DTIC Science & Technology

2007-05-01

protection against rotavirus infection of mice stimulated by intranasal immunization with chimeric VP4 or VP6 protein. J Virol 1999;73(9):7574–81. [13] Choi...AH, Basu M, McNeal MM, Flint J, VanCott JL, Clements JD, et al. Functional mapping of protective domains and epitopes in the rotavirus VP6 protein. J...McNeal MM, Rae MN, Bean JA, Ward RL. Antibody-dependent and -independent protection following intranasal immunization of mice with rotavirus particles. J

The Impact of Exercise on the Vulnerability of Dopamine Neurons to Cell Death in Animal Models of Parkinson’s Disease

DTIC Science & Technology

2008-07-01

increase in the apparent activity of MEK1/ 2 and a decrease in the apparent activity of protein phosphatase 2A. Third, the pro-survival protein Bcl - 2 ...2000. Correlation between structure of Bcl - 2 and its inhibitory function of JNK and caspase activity in dopa- minergic neuronal apoptosis. J Neurochem 74...Choi WS, Kim JE, Seo JW, O’Malley KL, Oh YJ. 1998. Over- expression of HA-Bax but not Bcl - 2 or Bcl -XL attenuates 6-hydroxy- dopamine-induced neuronal

Interrelationships of Prenatal and Postnatal Growth, Hormones, Diet, and Breast Cancer

DTIC Science & Technology

2006-03-01

Breslow NE, Day NE. Statistical methods in cancer research, vol. 1. The analysis of case-control studies, IARC Sci. Publ. 32, Lyon, IARC, 1980 . 9...weight (Ekbom et al, 1992; Innes et al, 2000; Michels et al, 1996; Sander- son et al, 1996). Conversely, high adolescent (Coates et al, 1999; Hislop et...Brinton and Swanson, 1992; Choi et al, 1978; Coates et al, 1999; Franceschi et al, 1996; Hislop et al, 1986; Le Marchand et al, 1988a; Pryor et al, 1989

Joint Services Electronics Program.

DTIC Science & Technology

1986-09-30

IEEE Computer Society Conference on Trends and Aplications , Gaithersburg, MD, 57-62, May 1983. R.W. Miksad, D.W. Choi and E.J. Powers, "Application of...Estimators for Weakl Nonlinear Esti’mation Problems, M.S. Thesis , Dept. of Electrica Engineering, University of Texas at Austin, May 1982. 7 %- (Page...Chen, J. Vac. Sci. Technol. 17,911 (1980). 6. N.I. Cho, Masters Thesis , unpublished. 7. EI-Saied M. Aly and J.P. Stark, J. Appl. Phys. 53(4), 3063

Methods for Imaging Shewanella Oneidensis MR-1 Nanofilaments

DTIC Science & Technology

2010-01-01

R.E., 1980. Flagella on Legionnaires ’ disease bacteria: ultrastructural observations. Ann. Intern. Med. 93, 711–714. Choi, C.Q., 2006. Nanowires...Perspective paper Methods for imaging Shewanella oneidensis MR-1 nanofilaments R. Ray a, S . Lizewski b, L.A. Fitzgerald b, B. Little a, B.R...Research Laboratory, 4555 Overlook Avenue, SW, Washington, DC. 20375, USA a b s t r a c ta r t i c l e i n f o Article history: Received 21 May 2010

Advanced Materials and Processing 2010

NASA Astrophysics Data System (ADS)

Zhang, Yunfeng; Su, Chun Wei; Xia, Hui; Xiao, Pengfei

2011-06-01

Strain sensors made from MWNT/polymer nanocomposites / Gang Yin, Ning Hu and Yuan Li -- Shear band evolution and nanostructure formation in titanium by cold rolling / Dengke Yang, Peter D. Hodgson and Cuie Wen -- Biodegradable Mg-Zr-Ca alloys for bone implant materials / Yuncang Li ... [et al.] -- Hydroxyapatite synthesized from nanosized calcium carbonate via hydrothermal method / Yu-Shiang Wu, Wen-Ku Chang and Min Jou -- Modeling of the magnetization process and orthogonal fluxgate sensitivity of ferromagnetic micro-wire arrays / Fan Jie ... [et al.] -- Fabrication of silicon oxide nanowires on Ni coated silicon substrate by simple heating process / Bo Peng and Kwon-Koo Cho -- Deposition of TiOxNy thin films with various nitrogen flow rate: growth behavior and structural properties / S.-J. Cho ... [et al.] -- Observation on photoluminescence evolution in 300 KeV self-ion implanted and annealed silicon / Yu Yang ... [et al.] -- Facile synthesis of lithium niobate from a novel precursor H[symbol] / Meinan Liu ... [et al.] -- Effects of the buffer layers on the adhesion and antimicrobial properties of the amorphous ZrAlNiCuSi films / Pai-Tsung Chiang ... [et al.] -- Fabrication of ZnO nanorods by electrochemical deposition process and its photovoltaic properties / Jin-Hwa Kim ... [et al.] -- Cryogenic resistivities of NbTiAlVTaLax, CoCrFeNiCu and CoCrFeNiAl high entropy alloys / Xiao Yang and Yong Zhang -- Modeling of centrifugal force field and the effect on filling and solidification in centrifugal casting / Wenbin Sheng, Chunxue Ma and Wanli Gu -- Electrochemical properties of TiO[symbol] nanotube arrays film prepared by anodic oxidation / Young-Jin Choi ... [et al.] -- Effect of Ce additions on high temperature properties of Mg-5Sn-3Al-1Zn alloy / Byoung Soo Kang ... [et al.] -- Sono-electroless plating of Ni-Mo-P film / Atsushi Chiba, Masato Kanou and Wen-Chang Wu -- Diameter dependence of giant magneto-impedance effect in co-based melt extracted amorphous

77 FR 35021 - Kwan Bo Jin, M.D.; Decision and Order

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-12

...' would as a matter of statutory interpretation logically encompass the factors listed in Section 824(a...) were employed in reaching this conclusion. Indeed, while factor five focuses on ``other conduct... exclusion provisions). In addition, construing factor five in this manner renders superfluous factor one...

Integrated Analysis of Piezoelectric Resonators as Components of Electronic Systems

DTIC Science & Technology

2015-09-07

Transient thickness-shear vibration of apiezoelectric plate of monoclinic crystals, International Journal of Applied Electromagnetics and Mechanics 38...52, 1461-1467 (2005)., (04 2012): 811. doi: N Liu, J S Yang, F Jin. Transient thickness-shear vibration of a piezoelectric plate of monoclinic...2012) 27–37, (02 2012): 27. doi: Zhi Wang, Minghao Zhao, Jiashi Yang. Amplitude evolution equation and transient effects in piezoelectric crystal

On Tradeoffs between Trust and Survivability using a Game Theoretic Approach

DTIC Science & Technology

2016-04-13

On Tradeoffs between Trust and Survivability using a Game Theoretic Approach Jin-Hee Cho and Ananthram Swami U.S. Army Research Laboratory...introduces a game theoretic approach, namely Aoyagi’s game theory based on positive collusion of players. This approach improves group trust by...communication and networking field [17]. We employ a game theoretic approach, namely Aoyagi’s game theory [2], to introduce the concept of positive

Modal Theory of Transverse Acoustic Coherence in Shallow Oceans

DTIC Science & Technology

2012-09-28

J. Ocean. Eng. 24(3), 333–345 (1999). 54. J. F. Lynch, G. Jin, R. Pawlowicz, D. Ray, A. J. Plueddenmann, C.-S. Chiu, J. H. Miller, R. H. Bourke , A. R...Theory and experiment,” J. Acoust. Soc. Am. 99(2), 803–821 (1996). 55. A. R. Parsons, R. H. Bourke , R. D. Muench, C.-S. Chiu, J. F. Lynch, J. H. Miller

Bottom-up Assembly of Engineered Protein Fibers

DTIC Science & Technology

2015-02-15

Formation and Small Molecule Recognition of Helical Proteins, Advanced Functional materials , (02 2012): 0. doi: Jasmin Hume, Jennifer Sun, Rudy Jacquet...2015 Received Paper 8.00 7.00 Jasmin Hume, Raymond Chen, Rudy Jacquet, Michael Yang, Jin Montclare. Tunable Conformation- Dependent Engineered...Received Book Chapter TOTAL: PERCENT_SUPPORTEDNAME FTE Equivalent: Total Number: Discipline Haresh More 1.00 Jasmin Hume 1.00 Joseph Frezzo 0.10 Rudy

Evaluating the Limits of Network Topology Inference Via Virtualized Network Emulation

DTIC Science & Technology

2015-06-01

76 xi Figure 5.33 Hop-plot of five best reduction methods. KDD most closely matches the Internet plot...respectively, located around the world. These monitors provide locations from which to perform network measurement experiments, primarily using the ping ...International Symposium on Modeling, Analysis and Simulation of Computer Telecommunication Systems. IEEE, 2001, pp. 346–353. 90 [21] C. Jin , Q. Chen, and S

Strategic Studies Quarterly. Volume 9, Number 2. Summer 2015

DTIC Science & Technology

2015-01-01

disrupting financial markets. Among other indicators, China’s already deployed and future Type 094 Jin -ciass nuclear ballistic missile submarines (SSBN...on agility instead of brute force re- inforces traditional Chinese military thinking. Since Sun Tzu, the acme of skill has been winning without... mechanical (both political and technical) nature of digital developments. Given this, the nature of system constraints under a dif- ferent future

PERSPECTIVE Working towards a community-wide understanding of satellite skin temperature observations

NASA Astrophysics Data System (ADS)

Shreve, Cheney

2010-12-01

With more than sixty free and publicly available high-quality datasets, including ecosystem variables, radiation budget variables, and land cover products, the MODIS instrument and the MODIS scientific team have contributed significantly to scientific investigations of ecosystems across the globe. The MODIS instrument, launched in December 1999, has 36 spectral bands, a viewing swath of 2330 km, and acquires data at 250 m, 500 m, and 1000 m spatial resolution every one to two days. Radiation budget variables include surface reflectance, skin temperature, emissivity, and albedo, to list a few. Ecosystem variables include several vegetation indices and productivity measures. Land cover characteristics encompass land cover classifications as well as model parameters and vegetation classifications. Many of these products are instrumental in constraining global climate models and climate change studies, as well as monitoring events such as the recent flooding in Pakistan, the unprecedented oil spill in the Gulf of Mexico, or phytoplankton bloom in the Barents Sea. While product validation efforts by the MODIS scientific team are both vigorous and continually improving, validation is unquestionably one of the most difficult tasks when dealing with remotely derived datasets, especially at the global scale. The quality and availability of MODIS data have led to widespread usage in the scientific community that has further contributed to validation and development of the MODIS products. In their recent paper entitled 'Land surface skin temperature climatology: benefitting from the strengths of satellite observations', Jin and Dickinson review the scientific theory behind, and demonstrate application of, a MODIS temperature product: surface skin temperature. Utilizing datasets from the Global Historical Climatological Network (GHCN), daily skin and air temperature from the Atmospheric Radiation Measurement (ARM) program, and MODIS products (skin temperature, albedo, land

VizieR Online Data Catalog: Morphologies of z<0.01 SDSS-DR7 galaxies (Ann+, 2015)

NASA Astrophysics Data System (ADS)

Ann, H. B.; Seo, M.; Ha, D. K.

2015-05-01

This paper presents a catalog of the morphological types of galaxies whose redshifts are less than z=0.01. The morphological types are determined by a visual inspection of the color images provided by SDSS DR7 (II/294). The majority of galaxies in the present sample come from the KIAS-VAGC (Choi et al. 2010JKAS...43..191C) which is based on the spectroscopic target galaxies of the SDSS DR7 complemented by the bright galaxies with known redshifts from various catalogs. (1 data file).

Tissue Preservation Assessment Preliminary Results

NASA Technical Reports Server (NTRS)

Globus, Ruth; Costes, Sylvain

2017-01-01

Pre-flight groundbased testing done to prepare for the first Rodent Research mission validation flight, RR1 (Choi et al, 2016 PlosOne). We purified RNA and measured RIN values to assess quality of the samples. For protein, we measured liver enzyme activities. We tested protocol and methods of preservation to date. Here we present an overview of results related to tissue preservation from the RR1 validation mission and a summary of findings to date from investigators who received RR1 teissues various Biospecimen Sharing Program.

Combination of anti-L1 cell adhesion molecule antibody and gemcitabine or cisplatin improves the therapeutic response of intrahepatic cholangiocarcinoma.

PubMed

Cho, Seulki; Lee, Tae Sup; Song, In Ho; Kim, A-Ram; Lee, Yoon-Jin; Kim, Haejung; Hwang, Haein; Jeong, Mun Sik; Kang, Seung Goo; Hong, Hyo Jeong

2017-01-01

Cholangiocarcinoma has a poor prognosis and is refractory to conventional chemotherapy and radiation therapy. Improving survival of patients with advanced cholangiocarcinoma urgently requires the development of new effective targeted therapies in combination with chemotherapy. We previously developed a human monoclonal antibody (mAb) Ab417 that binds to both the human and mouse L1 cell adhesion molecule (L1CAM) with high affinities. In the present study, we observed that Ab417 exhibited tumor targeting ability in biodistribution studies and dose-dependent tumor growth inhibition in an intrahepatic cholangiocarcinoma (Choi-CK) xenograft mouse model. Regarding the mechanism of action, Ab417 was internalized into the tumor cells and thereby down-regulated membrane L1CAM, and inhibited tumor growth by reducing tumor cell proliferation in vivo. Gemcitabine inhibited the tumor growth in a dose-dependent manner in the Choi-CK xenograft model. However, cisplatin inhibited the tumor growth moderately and not in a dose-dependent way, suggesting that the tumors may have developed resistance to apoptosis induced by cisplatin. Combined treatment with Ab417 and gemcitabine or cisplatin exerted enhanced tumor growth inhibition compared to treatment with antibody or drug alone. The results suggest that Ab417 in combination with chemotherapy may have potential as a new therapeutic regimen for cholangiocarcinoma. Our study is the first to show an enhanced therapeutic effect of a therapeutic antibody targeting L1CAM in combination with chemotherapy in cholangiocarcinoma models.

Analysis of biliary anatomy according to different classification systems.

PubMed

Deka, Pranjal; Islam, Mahibul; Jindal, Deepti; Kumar, Niteen; Arora, Ankur; Negi, Sanjay Singh

2014-01-01

Variations in biliary anatomy are common, and different classifications have been described. These classification systems have not been compared to each other in a single cohort. We report such variations in biliary anatomy on magnetic resonance cholangiopancreatography (MRCP) using six different classification systems. In 299 patients undergoing MRCP for various indications, biliary anatomy was classified as described by Couinaud (1957), Huang (1996), Karakas (2008), Choi (2003), Champetier (1994), and Ohkubo (2004). Correlation with direct cholangiography and vascular anatomy was done. Bile duct dimensions were measured. Cystic duct junction and pancreaticobiliary ductal junction (PBDJ) were classified. Normal biliary anatomy was noted in 57.8 %. The most common variants were Couinaud type D2, Choi type 3A, Huang type A1, Champetier type a, Ohkubo types D and J, and Karakas type 2a. The Ohkubo classification was the most appropriate; 3.1 % of right ducts and 6.3 % of left ducts with variant anatomy could not be classified using the Ohkubo classification. There was a good agreement between MRCP and direct cholangiography (ĸ = 0.9). Anomalous PBDJ was noted in 8.7 %. Variant biliary anatomy was not associated with gender (p = 0.194) or variant vascular anatomy (p = 0.24). Although each classification system has its merits and demerits, some anatomical variations cannot be classified using any of the previously described classifications. The Ohkubo classification system is the most applicable as it considers most clinically relevant variations pertinent to hepatobiliary surgery.

Dynamic Failure of Integrated Durable Hot Structure for Space Access Vehicles

DTIC Science & Technology

2009-08-01

in nonho- mogeneous solids, which is of the more practical importance, by assuming plane strain conditions. Later on Delale and Erdogan [11], Eischen...12] and Erdogan et al. [13] solved crack problems for non-homogeneous materials under quasi-static loading. With the introduction of FGMs, research on...fracture mechanics of nonhomo- geneous solids gained additional impetus. Jin and Noda [14], Konda and Erdo- gan [15] and Erdogan [16] obtained the

Characterization of an E3 Ubiquitin Ligase that Degrades Neurofibromin in Vitro and Vivo

DTIC Science & Technology

2012-04-01

andDuronio, R.J. (2008). Identifying determinants of cullin binding specificity among the three functionally different Drosophila melanogaster Roc...Deshaies and Joazeiro, 2009; Nakayama and Nakayama, 2006). Although a large number of F-box proteins were found in the human genome (Jin et al., 2004... genome walking (Figure S1A). The insertion disrupts theDevelopmentaSag transcript resulting in a truncated fusionmRNA that encodes partial Sag N

Functional Voice Outcomes After Thyroidectomy: An Assessment of the Dsyphonia Severity Index (DSI) After Thyroidectomy

DTIC Science & Technology

2010-01-01

patients in the objective NVO group demonstrated persistent signs of recurrent laryngeal nerve paralysis. Sub- jective and objective NVO patients were...DL, Montesinos MR, Tacchi VA, Moreno JC, Falco JE, Mezzadri NA, et al. Voice changes after thyroidectomy with- out recurrent laryngeal nerve injury. J...in a cancer hospital. Otolaryngol Head Neck Surg 2005;132:490-4. 10. Roy AD, Gardiner RH, Niblock WM. Thyroidectomy and the recurrent laryngeal nerve

Aurora-A Oncogene in Human Ovarian Cancer

DTIC Science & Technology

2006-11-01

AD_________________ Award Number: W81XWH-05-1-0021 TITLE: Aurora-A Oncogene in Human Ovarian... in Human Ovarian Cancer 5b. GRANT NUMBER W81XWH-05-1-0021 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER Jin Q. Cheng, M.D...is frequently altered in human ovarian cancer (1). Overexpressing Aurora-A induces centrosome amplification and G2/M cell cycle progression

DNA Transport in Nanoparticle Porous-Wall Nanochannels

DTIC Science & Technology

2015-08-04

Fabricated by Interferometric Lithography, Advanced Materials, (01 2011): 147. doi: 10.1002/adma.201001856 Anthony L. Garcia, Youn-Jin Oh, Gabriel ...Albuquerque NM 87131 Gabriel P. Lopez University of New Mexico 1 University of New Mexico Albuquerque NM 87131 Fabrication of Enclosed Nanochannels using...University of New Mexico Albuquerque NM 87131 Y N Gabriel P. Lopez University of New Mexico 1 University of New Mexico Albuquerque NM 87131 Dimiter N

3-D Acoustic Scattering from 2-D Rough Surfaces Using A Parabolic Equation Model

DTIC Science & Technology

2013-12-01

Frequency Acoustic Propagation in Shallow Water.” Journal of Oceanic Engineering, September 2011: 1–10. Liu, Jin Yuan, Chen Fen Huang, and Ping Chang...loss values at a constant depth. .............................52  xi LIST OF ACRONYMS AND ABBREVIATIONS FD Finite Difference MMPE Monterey...2013). First, at each range step ( xi ), the 3-D field is transformed from cross-range spatial variable (y) to cross-range wavenumber variable (ky

Friction and Wear Sciences for a Highly Durable Railgun Weapon

DTIC Science & Technology

2007-10-01

FFT- Based Numerical Methods for Elasto-Plastic Contacts of Nominally Flat Surfaces,” to appear in Journal of Applied Mechanics. 20. Jin, X...is the fusion enthalpy per unit mass, C!"" ~ = and ! ~ is a dimensionless coefficient and 100 ~ !" . Listed in Table I are the material’s...searching existing data sources, gathering and maintaining the data needed, and completing and reviewing the collection of information. Send comments

PARK2, a Large Common Fragile Site Gene, is Part of a Stress Response Network in Normal Cells that is Disrupted During the Development of Ovarian Cancer

DTIC Science & Technology

2005-01-01

expression was completely abrogated in all of the hepatocellular carcinoma cell lines that we examined, so we also introduced Parkin into two HCC...the paper was "Parkin gene alterations in Hepatocellular Carcinoma " by Fang Wang, Stacy Denison, Jin-Ping Lai, Leslie A. Phillips, Damien Montoya...Shridhar, Lewis R. Roberts, David I Smith. Parkin Gene Alterations in Hepatocellular Carcinoma . Genes, Chromosomes, & Cancer 2004; 40:85-96. 12 GENES

Undergraduate Training in Mammary Gland Biology and Breast Cancer

DTIC Science & Technology

2005-05-01

1994) Toward a Physiological Approach to Breast Cancer Prevention. Cancer Epidemiol Biomarkers Prev. 3(4): 353-364. 10. Thordarson , G., Jin, E...Yang, J., Rajkumar, L., Thordarson , G., Chen, X., and Nandi, S. (1999) Hormonal Prevention of Breast Cancer: Mimicking the protective effect of pregnancy...Proc. Natl. Acad. Sci., 96: 2520-2525. 19. Rajkumar, L., Guzman, R.C., Yang, J., Thordarson , G., Talamantes, F., Nandi, S. (2001) Short-term

Acute Exposure Guideline Levels (AEGLs) for Time Varying Toxic Plumes

DTIC Science & Technology

2014-09-12

Department of Defense, Washington Headquarters Services, Directorate for Information Operations and Reports (0704-0188), 1215 Jefferson Davis Highway...into the EAGLE system based on a single EPA table given as a 5 x 3 array of real density values (units mg/m3). These routines share the required...and Y. Jin, (2011), Development and testing of a Coupled Ocean-Atmosphere Mesoscale ensemble Prediction System COAMPS- OS). Ocean Dynamics, 61, 1937

Synthesis of Si Nanowires for an Anode Material of Li Batteries

DTIC Science & Technology

2007-12-04

Zhou, H. Li, H.P. Sun , D.P. Yu, Y.Q. Wang, X.J. Huang, L.Q. Chen, Z. Zhang, Appl. Phys. Lett. 75 (16) (1999) 2447 6. A.M. Wilson, B.M. Way, J.R. Dahn...Y. Liu, Electrochem. Commun. 5 (2003) 165 12. Tatsuo Umeno, Kenji Fukuda, Hongyu Wang, Nikolay Dimov, Takashi Iwao, Masaki Yoshio, Chem. Lett...Hansu Kim, Junghee Choi, Hun-Joon Sohn and Tak Kang, J. Electrochem. Soc. 146 (12) (1999) 4401 18. G.X. Wang, L. Sun , D.H. Bradhurst, S. Zhong, S.X. Dou

Zebrafish Model of NF1 for Structure-Function Analysis, Mechanisms of Glial Tumorigenesis, and Chemical Biology

DTIC Science & Technology

2015-08-01

Meng1,‡, Jimann Shin2, Arun Padmanabhan3, Daniel Cifuentes4, Antonio J. Giraldez4, A. Thomas Look2, Jonathan A. Epstein3, Nathan D. Lawson1,§ and Scot ...Geurts, A. M., Cost, G. J., Freyvert, Y., Zeitler, B., Miller, J. C., Choi, V. M., Jenkins, S. S., Wood , A., Cui, X., Meng, X. et al. (2009). Knockout...de Groh2,‡, Jeong-Soo Lee1,§, Sam Haidar3, Suzanne Dahlberg1, Feng Guo1, Shuning He1, Marc A. Wolman2, Michael Granato2, Nathan D. Lawson4, Scot A

Band-Edge Excitons in PbSe Nanocrystals and Nanorods

DTIC Science & Technology

2010-12-06

P. Alivisatos, Nano Lett. 7, 179 2007. 2 B. Dubertret, P. Skourides, D. J. Norris, V. Noireaux, A. H. Bri- vanlou, and A. Libchaber, Science 298...and V. I. Klimov, Nano Lett. 6, 424 2006. 9 A. J. Nozik, Chem. Phys. Lett. 457, 3 2008. 10 W. Ma, J. M. Luther, H. Zheng, Y. Wu, and A. P...Alivisatos, Nano Lett. 9, 1699 2009. 11 J. J. Choi, Y. F. Lim, M. B. Santiago-Berrios, M. Oh, B. R. Hyun, L. Sun, A. C. Bartnik, A. Goedhart, G. G

An Integrated Science-based methodology

EPA Pesticide Factsheets

The data is secondary in nature. Meaning that no data was generated as part of this review effort. Rather, data that was available in the peer-reviewed literature was used.This dataset is associated with the following publication:Tolaymat , T., A. El Badawy, R. Sequeira, and A. Genaidy. An integrated science-based methodology to assess potential risks and implications of engineered nanomaterials. Diana Aga, Wonyong Choi, Andrew Daugulis, Gianluca Li Puma, Gerasimos Lyberatos, and Joo Hwa Tay JOURNAL OF HAZARDOUS MATERIALS. Elsevier Science Ltd, New York, NY, USA, 298: 270-281, (2015).

[The research on the edition of Daquanbencao (Complete Collection of Materia Medica)].

PubMed

Li, Jian; Zhang, Wei; Zhang, Rui-xian

2009-07-01

Zhengleibencao (Classified Materia Medica) had been formed into several kinds of edition systems during its dissemination, among which there was the edition system of Daquanbencao (Complete Collection of Materia Medica). Daquanbencao was originally carved in the Jin dynasty, thereafter it was re-carved in the Yuan, Ming and Qing dynasties so as to form a series of editions such as the edition of Zhenyou in the second year of the Jin dynasty; the edition of the Zongwenshuyuan college in Dade renyan year of the Yuan dynasty; the WANG Qiu's carved edition of Shangyitang hall in the Ming dynasty; the carved edition of Jishanshuyuan, the Jishang mountain college in the Ming dynasty, the reprinted edition of PENG Duan-wu in the Ming dynasty, the supplementary edition of YANG Bi-da in the Qing dynasty;, and the carved edition of KE Feng-shi in the Qing dynasty. Among all the editions, Chongkanjingshizhengleidaquanbencao (Reprinted Classified Daquan Materia Medica from Historical Classics) was the representative one. As a representative of the above editions, the carved edition of WANG took the edition of the Zongwenshuyuan college of the Yuan dynasty as the original edition, but the images picture of materia medica adopted from the edition of Zhenghebencao (Materia Medica of the Zhenghe era).

Empirical modeling ENSO dynamics with complex-valued artificial neural networks

NASA Astrophysics Data System (ADS)

Seleznev, Aleksei; Gavrilov, Andrey; Mukhin, Dmitry

2016-04-01

The main difficulty in empirical reconstructing the distributed dynamical systems (e.g. regional climate systems, such as El-Nino-Southern Oscillation - ENSO) is a huge amount of observational data comprising time-varying spatial fields of several variables. An efficient reduction of system's dimensionality thereby is essential for inferring an evolution operator (EO) for a low-dimensional subsystem that determines the key properties of the observed dynamics. In this work, to efficient reduction of observational data sets we use complex-valued (Hilbert) empirical orthogonal functions which are appropriate, by their nature, for describing propagating structures unlike traditional empirical orthogonal functions. For the approximation of the EO, a universal model in the form of complex-valued artificial neural network is suggested. The effectiveness of this approach is demonstrated by predicting both the Jin-Neelin-Ghil ENSO model [1] behavior and real ENSO variability from sea surface temperature anomalies data [2]. The study is supported by Government of Russian Federation (agreement #14.Z50.31.0033 with the Institute of Applied Physics of RAS). 1. Jin, F.-F., J. D. Neelin, and M. Ghil, 1996: El Ni˜no/Southern Oscillation and the annual cycle: subharmonic frequency locking and aperiodicity. Physica D, 98, 442-465. 2. http://iridl.ldeo.columbia.edu/SOURCES/.KAPLAN/.EXTENDED/.v2/.ssta/

Epigenetic Therapy of Hematopoietic Malignancies: Novel Approaches for Tissue-Specific and Global Inhibition of EZH2 Enzymatic Activities

DTIC Science & Technology

2016-08-01

at the bottom are: 1. acute myeloid leukemia ; 2. B-cell lymphoblastic leukemia ; 3. chronic myeloid leukemia ; 4. Burkitt’s lymphoma; 5. diffuse large...Liu PP, Jin J, Chen J. PBX3 and MEIS1 Cooperate in Hematopoietic Cells to Drive Acute Myeloid Leukemias Characterized by a Core Transcriptome of the...perturbations by Arg882-mutated DNMT3A potentiate aberrant stem cell gene expression program and acute leukemia development. Cancer Cell 2016 July

Global Existence of Classical Solutions to the Equations of Motion for Materials with Fading Memory.

DTIC Science & Technology

1984-02-01

influence function , history value problems, classical solutions, global existence, decay. Work Unit Number 1 - Applied Analysis Sponsored by the United...introduce an " influence function " h, intended to JIN. characterize the rate at which memory fades, and construct an LP-type space of admissible...histories using the influence function as a weight. Here we use the term influence function to mean a positive, nonincreasing, real-valued function h e L (0

Parallel Algorithms for Computer Vision

DTIC Science & Technology

1990-04-01

NA86-1, Thinking Machines Corporation, Cambridge, MA, December 1986. [43] J. Little, G. Blelloch, and T. Cass. How to program the connection machine for... to program the connection machine for computer vision. In Proc. Workshop on Comp. Architecture for Pattern Analysis and Machine Intell., 1987. [92] J...In Proceedings of SPIE Conf. on Advances in Intelligent Robotics Systems, Bellingham, VA, 1987. SPIE. [91] J. Little, G. Blelloch, and T. Cass. How

A Role for Epigenetic Mechanisms in Organ-Specific Breast Cancer Metastasis

DTIC Science & Technology

2010-05-01

of origin. The neovasculature of tumors is typically leaky (Carmeliet and Jain, 2000; Rafii et al., 2003), a feature that would facilitate not only...and therapy selection in esophageal cancer. Cancer Cell 13, 441- 453. Rafii , S., Avecilla, S.T., and Jin, D.K. (2003). Tumor vasculature address book...origin. The neovasculature of tumors is typically leaky (Carmeliet and Jain, 2000; Rafii et al., 2003), a feature that would facilitate not only the

Optoelectronic Device Integration in Silicon (OpSIS)

DTIC Science & Technology

2015-10-26

silicon-on-insulator," Opt. Express 22, 17872-17879 (2014) Y. Yang, C. Galland, Y. Liu, K. Tan , R. Ding, Q. Li, K. Bergman, T. Baehr-Jones, M...Ding, Ran; Liu, Yang; Ayazi, Ali; Pinguet, Thierry; Harris, Nicholas C; Streshinsky, Matt; Lee, Poshen; Zhang, Yi; Lim, Andy Eu-Jin; “Ultralow drive...Ding, Ran; Harris, Nicholas C; Baehr-Jones, Tom; Hochberg, Michael; “Broadband on-chip optical non-reciprocity using phase modulators” Optics express

Pilot Line Development of High-Performance Thermal Insulation

DTIC Science & Technology

1989-09-01

with the fiber blend described, full attention was given to the problems of pilot pro- duction. C. Assembly of the Pilot Production Line and Initial...that virtually all possible static control steps had been taken, we presented the problem to the fiber manufacturer, TeiJin. They re- sponded by...1988. The line was operated continuously during production of the 5-roll sample se, as static generation within the fiber was no longer a problem

Statistical Modeling of Natural Backgrounds in Hyperspectral LWIR Data

DTIC Science & Technology

2016-09-06

extremely important for studying performance trades. First, we study the validity of this model using real hyperspectral data, and compare the relative...difficult to validate any statistical model created for a target of interest. However, since background measurements are plentiful, it is reasonable to...Golden, S., Less, D., Jin, X., and Rynes, P., “ Modeling and analysis of LWIR signature variability associated with 3d and BRDF effects,” 98400P (May 2016

Mouse Model for Aerosol Infection of Influenza (Postprint)

DTIC Science & Technology

2011-12-01

Min, J.-Y., Lamirande, E.W., Santos, C., Jin, H., Kemble, G. and Subbarao , K . (2011) Comparison of a live attenuated 2009 H1N1 vaccine with...AFRL-RX-TY-TP-2012-0010 MOUSE MODEL FOR AEROSOL INFECTION OF INFLUENZA POSTPRINT Rashelle S. McDonald, Brian K . Heimbuch Applied Research...AVAILABILITY STATEMENT 13. SUPPLEMENTARY NOTES 14. ABSTRACT 15. SUBJECT TERMS 16. SECURITY CLASSIFICATION OF: a. REPORT b . ABSTRACT c. THIS PAGE 17

The Development of an Electrostatically Safe Lead Styphnate Composition and the Reproduction of Lead Styphnate Mixtures by Wet Processes

DTIC Science & Technology

1946-10-01

possible replacements of gelatin:- H) ivie-,hyl cellulose (2) Sodium carboxy-methyl cellulose (3) AlbaJin (4) Casein (5) Gum arabio (6) Rei...there is no adequate explanation as to why some proteins such as casein and albuaen are unsatisfactory for use in the graphiting process; they have...stage, the continued addition of gelatin sensitises the excess graphite sol. so that the charge on the micelle is reduced to such an extent that

Performance Comparison of Feature Extraction Algorithms for Target Detection and Classification

DTIC Science & Technology

2013-01-01

Detection and Classification⋆ Soheil Bahrampour1 Asok Ray2 Soumalya Sarkar2 Thyagaraju Damarla3 Nasser M. Nasrabadi3 Keywords: Feature Extraction...USA email:soheil@psu.edu 2A. Ray and S. Sarkar are with the Department of Mechanical Engineering, Pennsylvania State University, University Park, PA...no. 1, pp. 22–29, 2001. [5] G. Mallapragada, A. Ray , and X. Jin, “Symbolic dynamic filtering and language measure for behavior identification of mobile

Temporal Behavior of the Intensity-Dependent Absorption in Photorefractive BaTiO3

DTIC Science & Technology

1988-06-01

George Brost , and Jim Rotg6 JUL o 8 88 i’rinh I S", h’r i.seuu,:h .Labor(mfries, I S Air For, Acudeu\\. (olorudo (180840 0) Jin J. Kim (n ’r for If0gh / whu...Phys. 59, 3363 (1986). that these observations can be explained by a multi- 6. G. A. Brost . R. A. Motes, J. R. Rotg , and J1. J. Kim, in pie-trap model

Naval War College Review. Volume 68, Number 1, Winter 2015

DTIC Science & Technology

2015-01-01

Company vessel Zhanshan� Meanwhile, Electro- Mechanical Branch squad leader Sun Weimin helps fix the ship’s stalled engine, enabling it to rejoin the es...Naval Fleet Pays Four-Day Good- will Visit to Cameroon,” People’s Daily Online, 4 June 2014, english�peopledaily�com�cn/; Sun Zhao and Huang Jin , eds... mechanical or equipment failure un- derwater require particular attention to quality control and regular maintenance� By no means all countries are capable of

Fusion of Tomography Tests for DNAPL Source Zone Characterization: Technology Development and Validation

DTIC Science & Technology

2011-07-01

alternative to the REV and fracture network concepts, pp. 533-561, Rock Mechanics : Proceedings of the 28th U.S. Symposium, Tucson, Arizona, edited by I.W...spatially integrated measure of residual DNAPL volume in the flow without causing disturbances to the source zone domain [ Jin et al., 1995; Nelson and...step. 6 Hydrological inversion has been a major focus of groundwater hydrology during the last three decades [see Yeh, 1986; Sun , 1994 and

Chemoprevention of Breast Cancer by Mimicking the Protective Effect of Early First Birth

DTIC Science & Technology

2010-06-01

Endocrinol 2002;16:2034–51. 7. Thordarson G, Jin E, Guzman RC, Swanson SM, Nandi S, Talamantes F. Refractoriness to mammary tumori- genesis in parous rats...nitrosourea-induced mammary carcinomas in female Lewis rats. Carcinogenesis 1999;20:623–8. 11. Rajkumar L, Guzman RC, Yang J, Thordarson G...Guzman RC, Yang J, Rajkumar L, Thordarson G, Chen X, Nandi S. Hormonal prevention of breast cancer: mimicking the protective effect of pregnancy. Proc

Changes in the cutting efficiency of different types of dental diamond rotary instrument with repeated cuts and disinfection.

PubMed

Bae, Jin-Hyuk; Yi, Jaeyoung; Kim, Sungtae; Shim, June-Sung; Lee, Keun-Woo

2014-01-01

Cutting efficiency is one of the most important factors to consider when a specific dental diamond rotary instrument is selected. However, the selection of a dental diamond rotary instrument is based on clinical experience rather than any scientific evidence. The purpose of this study was to identify how the cutting efficiency of different types of dental diamond rotary instrument changed with repeated cuts and disinfection. Four types of diamond rotary instrument from 2 dental manufacturers (Shofu, Jin Dental) were investigated with a high-speed air-turbine handpiece. The groups were as follows: S cham group (n=10): chamfer design from Shofu; J cham group (n=10): chamfer design from Jin Dental; S thin group (n=10): thin tapered design from Shofu; J thin group (n=10): thin tapered design from Jin Dental. Changes in the cutting efficiency of diamond rotary instruments on glass ceramic blocks were measured after repeated cuts. Changes in cutting efficiency also were measured for 30 diamond rotary instruments, the same type as those used in group J cham after disinfection with ethylene oxide gas, immersion in solution, or autoclaving. One-way ANOVA, 2-way ANOVA, and repeated-measures ANOVA were used to identify differences in cutting efficiency, in total cutting efficiency, and change trend in cutting efficiency (α=.05). The Tukey honestly significant difference method was used for the post hoc tests. The principal metal components of the diamond rotary instruments were detected with x-ray spectrometry. The mean (standard deviation [SD]) total cutting efficiency after 10 cuts in the 4 groups was in the following order: J cham group (0.210 ± 0.064 g/min) > S cham group (0.170 ± 0.064 g/min) > J thin group (0.130 ± 0.042 g/min) > S thin group (0.010 ± 0.040 g/min) (P<.05).The decrease in the cutting efficiency was greatest after the first cut. The cutting efficiency was not influenced by repeated disinfection. The cutting efficiencies of diamond rotary instruments

Matuyama/Brunhes Polarity Transition in Owens Lake, CA, Sediment

NASA Astrophysics Data System (ADS)

Liddicoat, Joseph; Kravchinsky, Vadim

2014-05-01

The complexity of the Matuyama/Brunhes (M/B) polarity transition is becoming better understood from investigations of volcanic rocks (Coe et al., 2004), loess (Jin et al., 2012; Evans et al., 2011; Kravchinsky, 2013), and marine (Clement and Opdyke, 1982; Hartl and Tauxe, 1996; Macri et al., 2010) and lacustrine (Valet et al., 1988; Sagnotti et al., 2013) sediments. The transition appears to include a brief interval of normal polarity prior to the entry into the Brunhes Normal Chron (Coe et al., 2004; Jin et al., 2012; Evans et al., 2011), and the transition has Virtual Geomagnetic Poles rapidly moving from the Southern Hemisphere to the Northern Hemisphere (Coe et al., 2004; Jin et al., 2012; Evans et al., 2011; Sagnotti et al., 2013). The M/B polarity transition is recorded in exposed Pleistocene lake sediments near Bishop, CA, where the brief interval of normal polarity noted above is present and the change from full reverse to full normal polarity occurs rapidly. The brief interval of normal polarity is recorded at two sites separated laterally by about 150 m and is in single hand samples measured at vertical spacing of 2.0-2.5 cm using six samples per measured level and alternating field demagnetization at 20 mT (Liddicoat, 1993, Table 1 and Fig. 8). The siltstone is unweathered glacial flour from the Sierra Nevada that borders the western side of Owens Valley where the sediments were deposited in Owens Lake. In the siltstone, the majority of the samples have a percentage of about 60 percent where the grain diameter is less than 63 micrometres, and in those samples there is about a five percent fraction when the diameter is two micrometres or less. The Total Inorganic Carbon in most samples is about 0.25 percent (Bergeron, 2013), and magnetite is the dominant carrier of the magnetization (Liddicoat, 1993). The palaeomagnetic directions recording the terminus of the full M/B transition, which occurs before the field intensity is completely recovered, spans no

[Characteristics of mercury pollution in soil and atmosphere in Songhua River upstream Jia-pi-gou gold mining area].

PubMed

Zhang, Gang; Wang, Ning; Wang, Yuan; Liu, Te; Ai, Jian-Chao

2012-09-01

In the studied area of Jia-pi-gou at the upstream area of Songhua River, algamation process has been applied as a dominant method to extract gold for more than one hundred and eighty years, resulting in severe mercury environmental pollution. The total mercury contents in the atmosphere and soil have been determined by mercury analyzer (Zeeman RA915+) and cold atomic absorption spectrophotometry (GB/T 17136-1997), respectively. To study the pollution characteristics of mercury in the soil and atmosphere, the mercury flux at the interface between the soil and the atmosphere of 4 sampling sites Lao-jin-chang, Er-dao-gou, Er-dao-cha and community of Jia-pi-gou have been determined with the method of dynamic flux chamber. Furthermore, linear regression analyses on the total mercury contents between soil and atmosphere have been carried out and the correlation coefficient of mercury exchange flux between soil and atmosphere and meteorological factors has been studied. The results are as follows: (1) The mean value of mercury content in the atmosphere is (71.08 +/- 38.22) ng x m(-3). (2) The mean value of mercury content in the soil is (0.913 1 +/- 0.040 8) mg x kg(-1); it shows remarkably positive correlation between the mercury contents in soil and in the atmosphere. (3) The mercury exchange flux between soil and atmosphere in different locations are Lao-jin-chang [(129.13 +/- 496.07) ng (m2 x h)(-1)], Er-dao-gou [(98.64 +/- 43.96) ng x (m2 x h)(-1)], Er-dao-cha [(23.17 +/- 171.23) ng x (m2 x h)(-1)], and community of Jia-pi-gou [(7.12 +/- 46.33) ng x (m2 x h)(-1)]. (4) Solar radiation is the major influential factor in the mercury exchange flux between the soil and atmosphere in Lao-jin-chang, Er-dao-cha and community of Jia-pi-gou. Solar radiation, air temperature and soil temperature jointly influence the process of the mercury exchange flux between the soil and atmosphere in Er-dao-gou. Under the disturbance of terrain, three noticeably distinctive trend features

Graphene Oxide Nanoribbon as Hole Extraction Layer to Enhance Efficiency and Stability of Polymer Solar Cells

DTIC Science & Technology

2013-01-01

Oxide Nanoribbon as Hole Extraction Layer to Enhance Effi ciency and Stability of Polymer Solar Cells Jun Liu , Gi-Hwan Kim , Yuhua Xue , Jin...circumvented by oxidizing graphene with acids (e.g., H 2 SO 4 /KMnO 4 ) to produce graphene oxide (GO) with oxygen-containing groups (e.g., –COOH, –OH...introducing the oxygen-rich groups around a graphene nanoribbon, the resultant graphene oxide nanoribbon (GOR) should show a synergistic effect to have

Chemoprevention of Breast Cancer by Mimicking the Protective Effect of Early First Birth

DTIC Science & Technology

2009-06-01

mammary gland. Mol Endocrinol 2002;16:2034–51. 7. Thordarson G, Jin E, Guzman RC, Swanson SM, Nandi S, Talamantes F. Refractoriness to mammary tumori... Thordarson G, Talamantes F, Nandi S. Short-term exposure to preg- nancy levels of estrogen prevents mammary carcino- genesis. Proc Natl Acad Sci U S...A 2001;98:11755–9. 12. Guzman RC, Yang J, Rajkumar L, Thordarson G, Chen X, Nandi S. Hormonal prevention of breast cancer: mimicking the protective

Chemoprevention of Breast Cancer by Mimicking the Protective Effect of Early First Birth

DTIC Science & Technology

2007-06-01

Mol Endocrinol 2002;16:2034–51. 7. Thordarson G, Jin E, Guzman RC, Swanson SM, Nandi S, Talamantes F. Refractoriness to mammary tumori- genesis in...methyl-N - nitrosourea-induced mammary carcinomas in female Lewis rats. Carcinogenesis 1999;20:623–8. 11. Rajkumar L, Guzman RC, Yang J, Thordarson G...11755–9. 12. Guzman RC, Yang J, Rajkumar L, Thordarson G, Chen X, Nandi S. Hormonal prevention of breast cancer: mimicking the protective effect of

Chemoprevention of Breast Cancer by Mimicking the Protective Effect of Early First Birth

DTIC Science & Technology

2011-06-01

Mol Endocrinol 2002;16:2034–51. 7. Thordarson G, Jin E, Guzman RC, Swanson SM, Nandi S, Talamantes F. Refractoriness to mammary tumori- genesis in...methyl-N - nitrosourea-induced mammary carcinomas in female Lewis rats. Carcinogenesis 1999;20:623–8. 11. Rajkumar L, Guzman RC, Yang J, Thordarson G...11755–9. 12. Guzman RC, Yang J, Rajkumar L, Thordarson G, Chen X, Nandi S. Hormonal prevention of breast cancer: mimicking the protective effect of

Proceedings of the Colloquium of the International Astronomical Union (127th). Reference Systems Held in Virginia Beach, Virginia on October 14-20, 1990

DTIC Science & Technology

1991-09-06

R.L. Duncombe, O.G. Franz, capabilities of the Hubble Space L.W. Fredrick, T. Gerard, Telescope fine guidance sensors P.D. Hemenway, B. McArthur, J...frame: Counterproposal to the Circular Letter no. 4 of Kovalevsky - I - .) 10. H. Eichhorn The organization of space : frames, systems and 97 standards...Heifets of REGATTA-ASTRO space astrometry program 48. W. Jin, T. Xu, Influence of systematic differences of FK4 on 280 P. Lu, and D. Liao determining

Technology and Application of Indium Phosphide and Related Semiconductors

DTIC Science & Technology

1989-03-01

Application and Insertion, GED-L 80/84-9, Oct 1984 1.2: M. Y. Yen , B. F. Levine, C. G. Bethea, K. K. Choi, and A. Y. Cho, Appl. Phys. Lett. 50 (1987) 927...Schlachetzki, Solid-State Electron. 28 (1985) 299 40 IV,A,5: F. B. Fank, J. D. Crowley, and J. J. Berenz, Microwave Journal, June 1979, p. 86 IV,A.6...Ser. 79 (1986) 703 IV,CIb.6: N. K. Dutta, S. G. Napholtz, R. Yen , R. L. Brown, T. M. Shen, N. A. Olsson, and D. C. Craft, Appl. Phys. Lett. 46 (1985

Dynamic Ring-on-Ring Equibiaxial Flexural Strength of Borosilicate Glass

DTIC Science & Technology

2010-01-01

Flexure Strength and Dynamic Fatigue of Soda – Lime – Silica Float Glass ,’’ J. Am. Ceram. Soc., 85 [7] 1777–1782 (2002). 9. A. Borger, R. Danzer, and P...on the Strength and Fatigue Behavior of Indented Soda – Lime Glass ,’’ Glass Technol., 32 [2] 51– 54 (1991). 16. J. J. Jr. Mecholsky, S. W. Freiman, and... Soda – Lime Glass Rods by a Statistical Approach,’’ J. Eur. Ceram. Soc., 11 341–346 (1993). 28. S. R. Choi and J. A. Salem, ‘‘Ultra-fast Fracture

A Study of the Tolerance of ROK Air Force Personnel to Gz Centrifugation,

DTIC Science & Technology

1980-12-09

A STUDY OF THE TOLERANCE OF ROK AIR FORCE PERSONNEL TO 6Z CENTR--ETC(U) DEC 80 B K LEE, J M HWANG, J S CHOIS UNCLASSIFIED FT-lrD(RS)T-1721-80 NL...DIVISION A STUDY OF THE TOLERANCE OF ROK AIR FORCE PERSONNEL TO+Gz CENTRIFUGATION by Byung Kook Lee, Jung Min Hwang, et al. 0 L..I IA - J Approved for public...Lieutenant Colonel 311 29 i94 1 2 6 Colonel 4 4 100 - Total j M7 1591’ 9 17 10 Conparin, the changes in heart rate of the pilots ar-d the ordinary per

Separability of three qubit Greenberger-Horne-Zeilinger diagonal states

NASA Astrophysics Data System (ADS)

Han, Kyung Hoon; Kye, Seung-Hyeok

2017-04-01

We characterize the separability of three qubit GHZ diagonal states in terms of entries. This enables us to check separability of GHZ diagonal states without decomposition into the sum of pure product states. In the course of discussion, we show that the necessary criterion of Gühne (2011 Entanglement criteria and full separability of multi-qubit quantum states Phys. Lett. A 375 406-10) for (full) separability of three qubit GHZ diagonal states is sufficient with a simpler formula. The main tool is to use entanglement witnesses which are tri-partite Choi matrices of positive bi-linear maps.

Hemorrhagic Fever with Renal Syndrome (Korean Hemorrhagic Fever)

DTIC Science & Technology

1988-06-30

camp 5/19(26%) n~t. n.t. 23 - 28 US Army camp 1/31(3%) 2/31(7%) 4/34 (13%) OK Army cimp 4/30(13%) 6/30(20%) 2/30(7%) 9 - 14 Chinhae 12/3,1 (35%) 2/34... data showed that 15% of the laboratory rats assayed from the Microbiology Department, School of Medicine, University of Buenos Aires, and 70% of the...Lee, M. C. and Cho, K. S. Management of Korean haemorrhagic fever. Med. Prog. 2: 15-21, 1980. 28. Lee, H. W., Bark, D. H., Baek, L. H., Choi, K. S

Suppression and enhancement of transcriptional noise by DNA looping

NASA Astrophysics Data System (ADS)

Vilar, Jose M. G.; Saiz, Leonor

2014-06-01

DNA looping has been observed to enhance and suppress transcriptional noise but it is uncertain which of these two opposite effects is to be expected for given conditions. Here, we derive analytical expressions for the main quantifiers of transcriptional noise in terms of the molecular parameters and elucidate the role of DNA looping. Our results rationalize paradoxical experimental observations and provide the first quantitative explanation of landmark individual-cell measurements at the single molecule level on the classical lac operon genetic system [Choi, L. Cai, K. Frieda, and X. S. Xie, Science 322, 442 (2008), 10.1126/science.1161427].

Source data supported high resolution carbon emissions inventory for urban areas of the Beijing-Tianjin-Hebei region: Spatial patterns, decomposition and policy implications.

PubMed

Cai, Bofeng; Li, Wanxin; Dhakal, Shobhakar; Wang, Jianghao

2018-01-15

This paper developed internationally compatible methods for delineating boundaries of urban areas in China. By integrating emission source data with existing official statistics as well as using rescaling methodology of data mapping for 1 km grid, the authors constructed high resolution emission gridded data in Beijing-Tianjin-Hebei (Jing-Jin-Ji) region in China for 2012. Comparisons between urban and non-urban areas of carbon emissions from industry, agriculture, household and transport exhibited regional disparities as well as sectoral differences. Except for the Hebei province, per capita total direct carbon emissions from urban extents in Beijing and Tianjin were both lower than provincial averages, indicating the climate benefit of urbanization, comparable to results from developed countries. Urban extents in the Hebei province were mainly industrial centers while those in Beijing and Tianjin were more service oriented. Further decomposition analysis revealed population to be a common major driver for increased carbon emissions but climate implications of urban design, economic productivity of land use, and carbon intensity of GDP were both cluster- and sector-specific. This study disapproves the one-size-fits-all solution for carbon mitigation but calls for down-scaled analysis of carbon emissions and formulation of localized carbon reduction strategies in the Jing-Jin-Ji as well as other regions in China. Copyright © 2017 Elsevier Ltd. All rights reserved.

MYC2 Differentially Modulates Diverse Jasmonate-Dependent Functions in Arabidopsis[W

PubMed Central

Dombrecht, Bruno; Xue, Gang Ping; Sprague, Susan J.; Kirkegaard, John A.; Ross, John J.; Reid, James B.; Fitt, Gary P.; Sewelam, Nasser; Schenk, Peer M.; Manners, John M.; Kazan, Kemal

2007-01-01

The Arabidopsis thaliana basic helix-loop-helix Leu zipper transcription factor (TF) MYC2/JIN1 differentially regulates jasmonate (JA)-responsive pathogen defense (e.g., PDF1.2) and wound response (e.g., VSP) genes. In this study, genome-wide transcriptional profiling of wild type and mutant myc2/jin1 plants followed by functional analyses has revealed new roles for MYC2 in the modulation of diverse JA functions. We found that MYC2 negatively regulates Trp and Trp-derived secondary metabolism such as indole glucosinolate biosynthesis during JA signaling. Furthermore, MYC2 positively regulates JA-mediated resistance to insect pests, such as Helicoverpa armigera, and tolerance to oxidative stress, possibly via enhanced ascorbate redox cycling and flavonoid biosynthesis. Analyses of MYC2 cis binding elements and expression of MYC2-regulated genes in T-DNA insertion lines of a subset of MYC2–regulated TFs suggested that MYC2 might modulate JA responses via differential regulation of an intermediate spectrum of TFs with activating or repressing roles in JA signaling. MYC2 also negatively regulates its own expression, and this may be one of the mechanisms used in fine-tuning JA signaling. Overall, these results provide new insights into the function of MYC2 and the transcriptional coordination of the JA signaling pathway. PMID:17616737

Provenance study of ancient Chinese Yaozhou porcelain by neutron activation analysis

NASA Astrophysics Data System (ADS)

Li, G. X.; Y Gao, Z.; Li, R. W.; Zhao, W. J.; Xie, J. Z.; Feng, S. L.; Zhuo, Z. X.; Y Fan, D.; Zhang, Y.; Cai, Z. F.; Liu, H.

2003-09-01

This paper reports our study of the provenance of ancient Chinese Yaozhou porcelain. The content of 29 elements in the Yaozhou porcelain samples was measured by neutron activation analysis (NAA). The NAA data were further analysed using fuzzy cluster analysis to obtain the trend fuzzy cluster diagrams. These samples with different glaze colour, ranging over more than 700 years, were fired in different kilns. Our analysis indicates the relatively concentrated distribution of the sources of the raw material for the Yaozhou porcelain body samples. They can be classified into two independent periods, i.e. the Tang (AD 618-907) and the Five Dynasties (AD 907-960) period, and the Song (AD 960-1279) and Jin (AD 1115-1234) period. Our analysis also indicates that the sources of the raw material for the ancient Yaozhou porcelain glaze samples are quite scattered and those for the black glaze in the Tang Dynasty are very concentrated. The sources of the raw material for the celadon glaze and the white glaze in the Tang Dynasty are widely distributed and those for the celadon glaze in the Song Dynasty are close to those of the bluish white glaze in the Jin Dynasty, and they are very concentrated. The sources of the raw material for the porcelain glazes cover those of the porcelain bodies.

Hemiparesis after Operation of Astrocytoma Grade II in Adults: Effects of Acupuncture on Sensory-Motor Behavior and Quality of Life

PubMed Central

Yu, Haibo; Schröder, Sven; Li, Zhifeng; Yang, Ying; Chen, Yu; Huang, Xingxian

2013-01-01

To evaluate the effect of acupuncture on hemiparesis and quality of life for adults with brain astrocytoma grade II, we conducted a randomized, observer-blinded clinical trial. Fifty-eight patients were randomized to standard rehabilitation (SR) therapy without acupuncture (n = 20), SR plus standard acupuncture (SA) (n = 19), and SR plus individualized acupuncture (IA) (n = 19). SA points were PC6, SP6, HT1, LU5, BL40, and ST36, while a special concept called “connecting and regulation Ren and Du” and “Jin-3-needling” served as IA. This treatment was individualized according to the clinical syndrome. The outcome was measured by the Barthel Index (BI), the Fugl-Meyer scale (FM), and the EORTC Core Quality of Life Questionnaire (QLQ-C30) with the Brain Cancer Module (BCM20). IA + SR reached significantly higher BI scores than SA + SR, which reached significantly higher BI scores than SR. IA + SR was significantly superior to SA + SR and to SR at the 8th week for the scores of FM motor and sensory assessments and most QLQ-C30-BCM20 items. In conclusion, the individualized acupuncture concept of “connecting and regulating Ren and Du” combined with “Jin-3-needling” offers a promising possibility for the treatment of hemiparesis due to astrocytoma, but further evaluation is mandatory. PMID:23864900

Alcohol-Induced Physiological Displacements and Their Effects on Flight-Related Functions

DTIC Science & Technology

1982-03-01

measured height and weight (6). One part bourbon per two parts of Coca Cola were mixed, divided equally into three drinks and drunk at an even rate over a...temporary protection against a plasma volume decrease (21). In our study, the imbibed volume of alcohol plus Coca Cola (about 350-550 ml) temporarily...amE E T Office of Aviation Medicine MAY 2 7 1982 Washington, D.C. 20591A~A C.-, t(Jin NOTICE This document is disseminated under the sponsorship of

Learning to Identify Local Flora with Human Feedback (Author’s Manuscript)

DTIC Science & Technology

2014-06-23

UNEP- WCMC, 2002. 1 [4] J . Hays and A. A. Efros. IM2GPS: estimating geographic informa- tion from a single image. In CVPR, 2008. 1 [5] R. Jin, S. Wang...and Y. Zhou. Regularized distance metric learning: Theory and algorithm. In NIPS, 2009. 2 [6] N. Kumar, P. Belhumeur, A. Biswas, D. Jacobs, W. J . Kress...I. Lopez, and J . Soare. Leafsnap: A computer vision system for automatic plant species identification. In ECCV, 2012. 1 [7] A. Oliva and A. Torralba

Multiscale Mathematics for Nano-Particle-Endowed Active Membranes and Films

DTIC Science & Technology

2016-08-03

Formation in Biofilms ,” Contemporary Mathematics (586), 2013, 105-116. 2. Yi Sun and Qi Wang, “Modeling and Simulations of Multicellular Aggregate Self...6402. 21. Hua Jiang, Hao Yang, Jun Zeng, Zhiyuan Zhou, Jin Peng, Qi Wang, Analytic Oncology, Electron J Metab Nutr Cancer ，Jun. 2015，Vol. 2， No. 2, 26...30. 22. Chen Chen, Dacheng Ren, Mingming Ren and Qi Wang, “3-D Spatial-Temporal Structures of Biofilms in A Water Channel,” Mathematical Methods

A new find of the fossil Cyclosorus from the Eocene of South China and its paleoclimatic implication.

PubMed

Naugolnykh, Serge V; Wang, Li; Han, Meng; Jin, Jian-Hua

2016-01-01

The thelypteroid ferns are widely distributed across tropical regions around the world, but information about their fossil representatives is scarce. A new species, Cyclosorus scutum Naugolnykh, Wang, Han et Jin was discovered from the Eocene Changchang Formation of Hainan Island, South China, and is described on the basis of sterile and fertile leaves, sori, sporangia and spores preserved in situ. Discovery of this new species clearly shows that climatic conditions of that time in this area were humid, i.e. warm and wet.

Electrical Characteristics of GaAs MESFET Fabrication by Ion Implantation of Si or Se

DTIC Science & Technology

1993-10-04

only the z-component of the polarization vector is non-zero, given by - dao . Since all the stress tensors are independent of z, the effective charge...GaAs," Stanford University, 1990. [381 Jong-Lam Lee , Jin Sup Kim, Hyung Moo Park, and Dong Sung Ma, "Depth Pro- files on Ion Implantation Induced Vacancy...February 1990. [40] Yao- Tsung Tsai and Timothy A. Grotjohn, "Source and Drain Resistance Studies of Short Channel MESFET’s Using Two-Dimensional Device

Ohio Army National Guard Mental Health Initiative: Risk and Resilience Factors for Combat-Related Posttraumatic Psychopathology and Post Combat Adjustment

DTIC Science & Technology

2012-10-01

data collection (beginning August 2012) thus far:  Telephone Survey N=1456 as of October 9, 2012:  Year 4 follow up interviews: N=1223  Dynamic...a0024663, Epub ahead of print ( August 8). Kessler, R.C., Berglund, P., Demler, O., Jin, R., Merikangas, K.R., Walters, E.E., 2005. Lifetime...administration closed on July 31, 2012. A summary of enrollment activity since the last CR is as follows (data reported as of August 31, 2012):  1,395

Neurotransmitter Mechanisms in the Nucleus Accumbens Septi and Related Regions in the Rat Brain.

DTIC Science & Technology

1981-06-30

1 WALAAS UNCLASSIFIED NORE/PUBL-81/1SS1 NL, 2 EEEEE JIN 1112.5 1 .8 125 1111 1.6____ MI(CFOPCl¥y RISOLLIIION I CSI HART % At LLffL 0...Nov 1 6 1981 A FORSVARETS FORSKNINGSINSTITUTT NORWEGIAN DEFENCE RESEARCH ESTABLISHMENT P 0 Box 25 - N-2007 Kjeiler, Norway This doaumot hamsi een,,-_j...CLASSIFICATION 3) NUMBER OF NI)RE/PUBL-8 1 /1001 UNCLA..SSIFIEDPAE IJUH NEFF fENCF 2j) OECLASSIFiCATION IOWNGRADING SCHEDULE 116 41 TITLE NEU

Symposium KK: Structure-Property Relationships in Biomineralized and Bio-mimetic Composites

DTIC Science & Technology

2010-04-06

Preventive and Restorative Dental Sciences, UCSF, San Francisco, California. 4:45 PM KK2.8 Damage and Crack Evolution in Mammalian Enamel James Jin...Technology, Graz, Austria. 9:45AMKK6.S AFM and PFM measurements of Enamel in order to Determine the Crack Tip Toughness and Cohesive Zone of Enamel Gerold...11:00 AM KK9.7 Enamel Matrix Guided Growth of Apatite Vuk Uskokovic1. Li Zhu2, Wu Li2 and Stefan Habelitz1; ’Department of Preventive and

Silicon Nanotips and Related Nano-Systems Involving Fluid and Carrier Transport and Their Micro-Devices for Power and Sensing Applications

DTIC Science & Technology

2011-05-10

Methanol’, Chien-Cheng Li, Ran-Jin Lin, Hong-Ping Lin, Ching-Chun Chang, Yu - Kai Lin, Li-Chyong Chen*, Kuei-Hsien Chen*, Chem. Comm. 47, 1473 (2011). (5...CuO-ZnO Inverse Opals as High-performance Methanol Microreformer’, Yan-Gu Lin, Yu -Kuei Hsu, San-Yuan Chen, Li-Chyong Chen* and Kuei-Hsien Chen*, J...Chun Lo, Hsin-I Hsiung, Surojit Chattopadhyay*, Hsieh -Cheng Han, Chia-Fu Chen*, Jih Perng Leu, Kuei-Hsien Chen and Li-Chyong Chen*, Biosens

Regeneration and Remodeling of Composite Materials

DTIC Science & Technology

2015-08-27

10.1002/adhm.201400084. [47] K. Jud, H.H. Kausch, J.G. Williams, Fracture mechanics studies of crack healing and welding of polymers, J. Mater. Sci...1.1. Archival publications resulting from the AFOSR Discovery grant 1. H. Jin , K.R. Hart, A.M. Coppola, R.C. Gergely, J.S. Moore, N.R. Sottos, S.R...Discovery grant 1. R.C.R. Gergely, J.S. Moore, N.R. Sottos, S.R. White, Regenerative Coatings, Society for Experimental Mechanics Annual Conference and

Deterrence and the United States Coast Guard: Enhancing Current Practice with Performance Measures

DTIC Science & Technology

2012-03-01

Talley,  Jin , Kite Powell,  The US Coast Guard Vessel Inspection Programme (2005)  Deterrence and the United States Coast Guard: Enhancing Current...practical problem-solving, not from theory or strategy. As a result, the activities are fractured and may not even be recognized as related to...of Sun Tzu’s admonition: “Strategy without tactics is the slowest route to victory. Tactics without strategy is the noise before defeat.” The US

Chinese Civil-Military Relations in the Post-Deng Era: Implications for Crisis Management and Naval Modernization (China Maritime Study, Number 4)

DTIC Science & Technology

2010-01-01

Nuclear Weapons Strategy: Tradition within Evolution (Lexington, Mass.: Lexington Books , 1988). 58. 金一南 [ Jin Yi’nan], “美在南海活动严重破坏中 国国家安全” [U.S...rivalries among the CCP central leadership and in Chinese society, which would have eroded civil-military boundaries and fractured the military’s cohesion... mechanization to RMA-based informatization. This made digitized operational platforms the top priorities for acquisition. Because these items are technology

Chemoprevention of Breast Cancer by Mimicking the Protective Effect of Early First Birth

DTIC Science & Technology

2006-06-01

and differentiation in the rodent mammary gland. Mol Endocrinol 2002;16:2034–51. 7. Thordarson G, Jin E, Guzman RC, Swanson SM, Nandi S, Talamantes F...8. 11. Rajkumar L, Guzman RC, Yang J, Thordarson G, Talamantes F, Nandi S. Short-term exposure to preg- nancy levels of estrogen prevents mammary...carcino- genesis. Proc Natl Acad Sci U S A 2001;98:11755–9. 12. Guzman RC, Yang J, Rajkumar L, Thordarson G, Chen X, Nandi S. Hormonal prevention of

Synchronism of nonlinear internal waves in a three-layer fluid

NASA Astrophysics Data System (ADS)

Talipova, Tatiana; Kurkina, Oxana; Terletska, Katerina; Rouvinskaya, Ekaterina

2017-04-01

In a three layer fluid with arbitrary layer widths and densities the existence of long internal solitons and breathers is proven theoretically and numerically, see for example (Pelinovsky et al., 2007; Lamb et al., 2007). The existence of breather-like waves of the intermediate length is also shown in numerical simulations (Terletska et al., 2016). For such waves conditions of synchronism are valid when a breather of the first mode and a soliton of the second mode move together with the same speed and form an asymmetric solitary wave of the second mode. The process of strong interaction of long nonlinear internal waves in the framework of three-layer Camassa-Choi model demonstrates the same effect (Jo&Choi, 2014; Barros, 2016). We analyze possible synchronism conditions for steady-state internal waves in a three-layer fluid analytically the framework of the Gardner equation, which is valid for long weakly nonlinear internal waves. The equations for synchronism conditions are derived and considered in terms of wave amplitudes, layer widths and density jumps. The configurations of three-layer fluid are found for which such a synchronism is possible. References: Barros R. Large amplitude internal waves in three-layer flows. The forth international conference "Nonlinear Waves - Theory and Applications", MS7, Beijing, China, June 25 - 28, 2016 Pelinovsky E., Polukhina O., Slunyaev A., Talipova T. Internal solitary waves // Chapter 4 in the book "Solitary Waves in Fluids". WIT Press. Southampton, Boston. 2007. P. 85 - 110. K. Terletska., K. T. Jung, T. Talipova, V. Maderich, I. Brovchenko and R. Grimshaw Internal breather-like wave generation by the second mode solitary wave interaction with a step// Physics of Fluids, 2016, accepted

Effects of aging on the fraction distribution and bioavailability of selenium in three different soils.

PubMed

Li, Jun; Peng, Qin; Liang, Dongli; Liang, Sijie; Chen, Juan; Sun, Huan; Li, Shuqi; Lei, Penghui

2016-02-01

Aging refers to the processes by which the mobility and bioavailability of metals in soil decline with time. Although long-term aging is a key process that needs to be considered in risk assessment of metals, few investigations has been attempted to determine whether and how residence time influences the selenium (Se) fractions and bioavailability in soil. In this study, the fractions of Se in soils was evaluated, and bioavailability were assessed by measuring Se concentration in pak choi (Brassica chinensis L.). Results showed that the change of soil available Se in all tested soils divided into two phases: rapid decrease at the initial time (42 d) and slow decline thereafter. The second-order equation could describe the decrease processes of available Se in tested soils during the entire incubation time (R(2) > 0.99), while parabolic diffusion equation had less goodness of fit. Those results indicated that Se aging was controlled not only by diffusion process but also by other processes such as nucleation/precipitation, adsorption/desorption with soil component, occlusion by organic matter and reduction reaction. Soil available Se fractions tended to transform to more stable fractions during aging. The changes of Se concentration in pak choi were consistent with the variation in soil available Se content. In addition, 21 d could be reference for the time of Se aging reaching stabilization in krasnozems and fluvo-aquic soil, and 30 d for black soil. Results could provide theoretical basis to formulate environmental quality criterion and choose the equilibrium time before implementing a pot experiment in Se-spiked soils. Copyright © 2015 Elsevier Ltd. All rights reserved.

Genomic inferences of domestication events are corroborated by written records in Brassica rapa.

PubMed

Qi, Xinshuai; An, Hong; Ragsdale, Aaron P; Hall, Tara E; Gutenkunst, Ryan N; Chris Pires, J; Barker, Michael S

2017-07-01

Demographic modelling is often used with population genomic data to infer the relationships and ages among populations. However, relatively few analyses are able to validate these inferences with independent data. Here, we leverage written records that describe distinct Brassica rapa crops to corroborate demographic models of domestication. Brassica rapa crops are renowned for their outstanding morphological diversity, but the relationships and order of domestication remain unclear. We generated genomewide SNPs from 126 accessions collected globally using high-throughput transcriptome data. Analyses of more than 31,000 SNPs across the B. rapa genome revealed evidence for five distinct genetic groups and supported a European-Central Asian origin of B. rapa crops. Our results supported the traditionally recognized South Asian and East Asian B. rapa groups with evidence that pak choi, Chinese cabbage and yellow sarson are likely monophyletic groups. In contrast, the oil-type B. rapa subsp. oleifera and brown sarson were polyphyletic. We also found no evidence to support the contention that rapini is the wild type or the earliest domesticated subspecies of B. rapa. Demographic analyses suggested that B. rapa was introduced to Asia 2,400-4,100 years ago, and that Chinese cabbage originated 1,200-2,100 years ago via admixture of pak choi and European-Central Asian B. rapa. We also inferred significantly different levels of founder effect among the B. rapa subspecies. Written records from antiquity that document these crops are consistent with these inferences. The concordance between our age estimates of domestication events with historical records provides unique support for our demographic inferences. © 2017 John Wiley & Sons Ltd.

[Application of fuzzy mathematics on modifying taste of oral solution of traditional Chinese drug].

PubMed

Wang, Youjie; Feng, Yi; Zhang, Bo

2009-01-01

To apply Fuzzy mathematical methods to choose the best taste modifying prescription of oral solution of traditional Chinese drug. Jin-Fukang oral solution was used as a model drug. The oral solution was prepared in different taste modifying prescriptions, whose tastes were evaluated by the fuzzy quality synthetic evaluation system. Compound-sweeteners with Sucralose and Erythritol was the best choice. Fuzzy integrated evaluation can be used to evaluate the taste of traditional Chinese medicinal pharmaceuticals, which overcame the artificial factors and achieve more objective conclusion.

Systematic Search for Gene-Gene Interaction Effect on Prostate Cancer Risk

DTIC Science & Technology

2013-07-01

Systematic Search for Gene-Gene Interaction 5a. CONTRACT NUMBER Effect on Prostate Cancer Risk 5b. GRANT NUMBER W81XWH-09-1-0488 5c. PROGRAM...Supported by this grant ) 1. Tao S, Wang Z, Feng J, Hsu FC, Jin G, Kin ST, Zhang Z, Gronberg H, Zheng, SL, Isaacs WB, XU J, Sun J. A Genome-Wide Search for...order interactions among estrogen- metabolism genes in sporadic breast cancer. Am J Hum Genet, 69, 138-47. 48. Marchini, J., Donnelly, P. and Cardon

Chemoprevention of Breast Cancer by Mimicking the Protective Effect of Early First Birth. Addendum

DTIC Science & Technology

2013-03-01

changes in growth factors, TGF-h3, and differentiation in the rodent mammary gland. Mol Endocrinol 2002;16:2034–51. 7. Thordarson G, Jin E, Guzman RC...rats. Carcinogenesis 1999;20:623–8. 11. Rajkumar L, Guzman RC, Yang J, Thordarson G, Talamantes F, Nandi S. Short-term exposure to preg- nancy levels of...estrogen prevents mammary carcino- genesis. Proc Natl Acad Sci U S A 2001;98:11755–9. 12. Guzman RC, Yang J, Rajkumar L, Thordarson G, Chen X, Nandi S

Chemoprevention of Breast Cancer by Mimicking the Protective Effect of Early First Birth

DTIC Science & Technology

2008-06-01

growth factors, TGF-h3, and differentiation in the rodent mammary gland. Mol Endocrinol 2002;16:2034–51. 7. Thordarson G, Jin E, Guzman RC, Swanson...Carcinogenesis 1999;20:623–8. 11. Rajkumar L, Guzman RC, Yang J, Thordarson G, Talamantes F, Nandi S. Short-term exposure to preg- nancy levels of...estrogen prevents mammary carcino- genesis. Proc Natl Acad Sci U S A 2001;98:11755–9. 12. Guzman RC, Yang J, Rajkumar L, Thordarson G, Chen X, Nandi S

Zircon U-Pb Geochronology, Hf Isotopic Composition and Geological Implications of the Neoproterozoic Huashan Group in the Jingshan Area, Northern Yangtze Block, China

NASA Astrophysics Data System (ADS)

Yang, Z.; Yang, K.

2015-12-01

In the northern Yangtze Block, a clear angular unconformity between the Mesoproterozoic sequences (e.g. Dagushi Group) and the overlying Neoproterozoic strata (e.g. Huashan Group) marks the the Jinning orogeny. A combined study of Lu-Hf isotopes and U-Pb ages for detrital zircons from Huashan Group can provide information on the crustal evolution of sedimentary provenances and the timing of the Jinning orogeny. Detrital zircons from Huashan Group have two major U-Pb age populations of about 2.0Ga, 2.65Ga, and three subordinate age groups of about 0.82Ga, 2.5Ga, 2.9Ga with minor >3.0Ga ages. The youngest five analyses yield a weighted average age of 816±9Ma, which is consistent with that of interlayered basalt (824±9Ma, Deng et al., 2013) and roughly defines the minimum depositional age of Huashan Group. Detrital zircons of Huashan Group mostly have two stage Hf isotope model ages (TDM2) between 3.0 to 3.3Ga, indicating that the northern Yangtze Block experienced significant continental crustal growth during the Paleo- to Meso-archean. Similar U-Pb ages of detrital zircons have been obtained from Precambrian sedimentary rocks in the northern Yangtze Block from previous studies (Liu et al., 2008; Guo et al., 2014 and references therein). Recently, ca. 2.65Ga A-type granites had been reported from the Kongling and Huji area, which likely record the thermally stable lithosphere (Chen et al., 2013; Zhou et al., 2015). In combination with this study, it documents the widespread 2.6-2.7Ga magmatic rocks in the northern Yangtze Block. Zhao et al. (2013) demonstrated both the ca. 850Ma tonalite and trondhjemite of the Huangling igneous complex were formed in a continental arc setting. This suggests the Miaowan-Huashan oceanic basin proposed by Bader et al. (2013) has not been closed at ca. 850Ma. This evidence, together with the depositional age of the Huashan Group, indicates the Jinning orogeny took place at 850-820 Ma. [1] Bader et al., 2013 Tectonics [2] Deng et al

An evaluation of the schemes of ocean surface albedo parameterization in shortwave radiation estimation

NASA Astrophysics Data System (ADS)

Niu, Hailin; Zhang, Xiaotong; Liu, Qiang; Feng, Youbin; Li, Xiuhong; Zhang, Jialin; Cai, Erli

2015-12-01

The ocean surface albedo (OSA) is a deciding factor on ocean net surface shortwave radiation (ONSSR) estimation. Several OSA schemes have been proposed successively, but there is not a conclusion for the best OSA scheme of estimating the ONSSR. On the base of analyzing currently existing OSA parameterization, including Briegleb et al.(B), Taylor et al.(T), Hansen et al.(H), Jin et al.(J), Preisendorfer and Mobley(PM86), Feng's scheme(F), this study discusses the difference of OSA's impact on ONSSR estimation in condition of actual downward shortwave radiation(DSR). Then we discussed the necessity and applicability for the climate models to integrate the more complicated OSA scheme. It is concluded that the SZA and the wind speed are the two most significant effect factor to broadband OSA, thus the different OSA parameterizations varies violently in the regions of both high latitudes and strong winds. The OSA schemes can lead the ONSSR results difference of the order of 20 w m-2. The Taylor's scheme shows the best estimate, and Feng's result just following Taylor's. However, the accuracy of the estimated instantaneous OSA changes at different local time. Jin's scheme has the best performance generally at noon and in the afternoon, and PM86's is the best of all in the morning, which indicate that the more complicated OSA schemes reflect the temporal variation of OWA better than the simple ones.

Microfluidics Transport and Path Control via Programmable Electrowetting on Dielectric

DOE Office of Scientific and Technical Information (OSTI.GOV)

Theodore W. Von Bitner, Ph.D.

2002-08-22

This research was conducted in collaboration with Professor Chang-Jin Kim of the University of California, Los Angeles. In phase I, the IOS-UCLA collaboration demonstrated the transport and manipulation of insulting liquid droplets using the principles of EWOD. A postage stamp sized array of electronically addressable Teflon pads, whose surface tension characteristics could be altered on command through computer algorithms, was developed and tested using deionized water as the liquid. Going beyond the tasks originally proposed for Phase I, droplet manipulation was achieved and droplet stability in the EWOD device was examined.

Underground laboratories in Asia

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lin, Shin Ted, E-mail: linst@mails.phys.sinica.edu.tw; Yue, Qian, E-mail: yueq@mail.tsinghua.edu.cn

2015-08-17

Deep underground laboratories in Asia have been making huge progress recently because underground sites provide unique opportunities to explore the rare-event phenomena for the study of dark matter searches, neutrino physics and nuclear astrophysics as well as the multi-disciplinary researches based on the low radioactive environments. The status and perspectives of Kamioda underground observatories in Japan, the existing Y2L and the planned CUP in Korea, India-based Neutrino Observatory (INO) in India and China JinPing Underground Laboratory (CJPL) in China will be surveyed.

Underground laboratories in Asia

NASA Astrophysics Data System (ADS)

Lin, Shin Ted; Yue, Qian

2015-08-01

Deep underground laboratories in Asia have been making huge progress recently because underground sites provide unique opportunities to explore the rare-event phenomena for the study of dark matter searches, neutrino physics and nuclear astrophysics as well as the multi-disciplinary researches based on the low radioactive environments. The status and perspectives of Kamioda underground observatories in Japan, the existing Y2L and the planned CUP in Korea, India-based Neutrino Observatory (INO) in India and China JinPing Underground Laboratory (CJPL) in China will be surveyed.

A Local Probe for Universal Non-equilibrium Dynamics

DTIC Science & Technology

2015-06-01

left in the ground 1T. E. Drake, Y . Sagi, R. Paudel, J. T. Stewart, J. P . Gaebler, and D. S. Jin, “ Direct observation of the fermi surface in an...bottom) allow to switch the laser fast and fine-tune the frequency. “λ/2” refers to half-wave plates, “λ/4” refers to quarter-wave plates, and all cubes...the beat note signal on a fast photodiode. state (|F = 9/2,mF = −7/2〉), any place where excitation light exists. Imaging atoms occurs on a cycling

On exponential stability of linear Levin-Nohel integro-differential equations

NASA Astrophysics Data System (ADS)

Tien Dung, Nguyen

2015-02-01

The aim of this paper is to investigate the exponential stability for linear Levin-Nohel integro-differential equations with time-varying delays. To the best of our knowledge, the exponential stability for such equations has not yet been discussed. In addition, since we do not require that the kernel and delay are continuous, our results improve those obtained in Becker and Burton [Proc. R. Soc. Edinburgh, Sect. A: Math. 136, 245-275 (2006)]; Dung [J. Math. Phys. 54, 082705 (2013)]; and Jin and Luo [Comput. Math. Appl. 57(7), 1080-1088 (2009)].

Outer rotation curve of the Galaxy with VERA. III. Astrometry of IRAS 07427-2400 and test of the density-wave theory

NASA Astrophysics Data System (ADS)

Sakai, Nobuyuki; Nakanishi, Hiroyuki; Matsuo, Mitsuhiro; Koide, Nagito; Tezuka, Daisuke; Kurayama, Tomoharu; Shibata, Katsunori M.; Ueno, Yuji; Honma, Mareki

2015-08-01

We report the trigonometric parallax of IRAS 07427-2400 with VERA to be 0.185 ± 0.027 mas, corresponding to a distance of 5.41^{+0.92}_{-0.69}kpc. The result is consistent with the previous result of 5.32^{+0.49}_{-0.42}kpc obtained by Choi et al. (2014, ApJ, 790, 99) within error. To remove the effect of internal maser motions (e.g., random motions), we observed six maser features associated with IRAS 07427-2400 and determined systematic proper motions of the source by averaging proper motions of the six maser features. The obtained proper motions are (μαcos δ, μδ) = (-1.79 ± 0.32, 2.60 ± 0.17) mas yr-1 in equatorial coordinates, while Choi et al. (2014) showed (μαcos δ, μδ) = (-2.43 ± 0.02, 2.49 ± 0.09) mas yr-1 with one maser feature. Our astrometry results place the source in the Perseus arm, the nearest main arm in the Milky Way. Using our result with previous astrometry results obtained from observations of the Perseus arm, we conducted direct (quantitative) comparisons between 27 astrometry results and an analytic gas dynamics model based on the density-wave theory, obtaining two results. First is the pitch angle of the Perseus arm determined by VLBI astrometry, 11.1° ± 1.4°, differing from what is determined by the spiral potential model (probably traced by stars), ˜ 20°. The second is an offset between a dense gas region and the bottom of the spiral potential model. The dense gas region traced by VLBI astrometry is located downstream of the spiral potential model, which was previously confirmed in the nearby grand-design spiral galaxy M 51 in Egusa, Koda, and Scoville (2011, ApJ, 726, 85).

Multi-color phase imaging and sickle cell anemia (Conference Presentation)

NASA Astrophysics Data System (ADS)

Hosseini, Poorya; Zhou, Renjie; Yaqoob, Zahid; So, Peter T. C.

2016-03-01

Quantitative phase measurements at multiple wavelengths has created an opportunity for exploring new avenues in phase microscopy such as enhancing imaging-depth (1), measuring hemoglobin concentrations in erythrocytes (2), and more recently in tomographic mapping of the refractive index of live cells (3). To this end, quantitative phase imaging has been demonstrated both at few selected spectral points as well as with high spectral resolution (4,5). However, most of these developed techniques compromise imaging speed, field of view, or the spectral resolution to perform interferometric measurements at multiple colors. In the specific application of quantitative phase in studying blood diseases and red blood cells, current techniques lack the required sensitivity to quantify biological properties of interest at individual cell level. Recently, we have set out to develop a stable quantitative interferometric microscope allowing for measurements of such properties for red cells without compromising field of view or speed of the measurements. The feasibility of the approach will be initially demonstrated in measuring dispersion curves of known solutions, followed by measuring biological properties of red cells in sickle cell anemia. References: 1. Mann CJ, Bingham PR, Paquit VC, Tobin KW. Quantitative phase imaging by three-wavelength digital holography. Opt Express. 2008;16(13):9753-64. 2. Park Y, Yamauchi T, Choi W, Dasari R, Feld MS. Spectroscopic phase microscopy for quantifying hemoglobin concentrations in intact red blood cells. Opt Lett. 2009;34(23):3668-70. 3. Hosseini P, Sung Y, Choi Y, Lue N, Yaqoob Z, So P. Scanning color optical tomography (SCOT). Opt Express. 2015;23(15):19752-62. 4. Jung J-H, Jang J, Park Y. Spectro-refractometry of individual microscopic objects using swept-source quantitative phase imaging. Anal Chem. 2013;85(21):10519-25. 5. Rinehart M, Zhu Y, Wax A. Quantitative phase spectroscopy. Biomed Opt Express. 2012;3(5):958-65.

Organic soil production from urban soil, spent mushroom substrate, and other additives

NASA Astrophysics Data System (ADS)

Pham, Nhung Thi Ha

2017-09-01

In recent years, spent mushroom substrate (SMS) is becoming the huge problem in environmental pollution issues from mushroom production. However, SMS is also a nutrient-rich ogranic material with available nutrients and high porosity. Therefore, the value of products made from SMS should be exploited to take full advantage of agricultural by-product, support organic agriculture development without environmental pollution. The research has built 5 experimental formulas (4 mixed formulas and 1 control formulas with only urban soil). The analysis results of soil samples from mixed formulas and the control formula witness a significant increase in moisture and OM of mixed formulas (moisture from 36-42%, OM from 5.5-6.9%) after 20 treatment days, and N-P-K contents are also improved remarkably. 60 days later, soil nutrients in mixed formulas continue to rise, with highest OM (8.679%) at CT1; N (0.154%) at CT4; K2O (0,698%) and P2O5 (0,172%) at CT3, in addition, heavy metal contents in all formulas are under standard limit. Synthetic assessment of all norms indicates that the best organic soil product comes from CT3. The pak choi planting experiments are performed show that the growth of plants cultivated on organic soil products made from mixed formulas are much better than plants are grown on initially soil, and they also have no pestilent insect. Specially, pak choi planted on organic soil from CT3 have sharp developing with excellent tolerance ability, quantity and area of leaves are high. Thus, CT3 is the most suitable formula to increase soil nutrients, to solve spent mushroom subtrate streament problems after harvest, and for sustainable agricultural development.

Exact closed-form solutions of a fully nonlinear asymptotic two-fluid model

NASA Astrophysics Data System (ADS)

Cheviakov, Alexei F.

2018-05-01

A fully nonlinear model of Choi and Camassa (1999) describing one-dimensional incompressible dynamics of two non-mixing fluids in a horizontal channel, under a shallow water approximation, is considered. An equivalence transformation is presented, leading to a special dimensionless form of the system, involving a single dimensionless constant physical parameter, as opposed to five parameters present in the original model. A first-order dimensionless ordinary differential equation describing traveling wave solutions is analyzed. Several multi-parameter families of physically meaningful exact closed-form solutions of the two-fluid model are derived, corresponding to periodic, solitary, and kink-type bidirectional traveling waves; specific examples are given, and properties of the exact solutions are analyzed.

Ion-ion charge exchange processes. Final technical report, June 1, 1977-May 31, 1978

DOE Office of Scientific and Technical Information (OSTI.GOV)

Poe, R.T.; Choi, B.H.

Under the auspices of ERDA, we have undertaken a vigorous study of ion-ion charge exchange process pertinent to the storage-ring configurations in the heavy-ion fusion program. One particular reaction, singly charged helium charge exchange, was investigated in detail. General trend of the singly charged heavy-ion charge exchange reaction can be inferred from the present study. Some of our results were presented at Proceedings of the Heavy-Ion Fusion Workshop, Argonne National Laboratory (September 1978) as a paper entitled Charge Exchange Between Singly Ionized Helium Ions, by B.H. Choi, R.T. Poe and K.T. Tang. Here, we briefly describe our method and reportmore » the results.« less

Application of a fast sorting algorithm to the assignment of mass spectrometric cross-linking data.

PubMed

Petrotchenko, Evgeniy V; Borchers, Christoph H

2014-09-01

Cross-linking combined with MS involves enzymatic digestion of cross-linked proteins and identifying cross-linked peptides. Assignment of cross-linked peptide masses requires a search of all possible binary combinations of peptides from the cross-linked proteins' sequences, which becomes impractical with increasing complexity of the protein system and/or if digestion enzyme specificity is relaxed. Here, we describe the application of a fast sorting algorithm to search large sequence databases for cross-linked peptide assignments based on mass. This same algorithm has been used previously for assigning disulfide-bridged peptides (Choi et al., ), but has not previously been applied to cross-linking studies. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

[Textual research on Chen Ye and his Jia cang jing yan fang (Family-preserved Empirical Recipes) of the Song Dynasty].

PubMed

Zhang, Xuedan; Zhang, Ruqing; Chen, Dexing

2014-01-01

Chen Ye, an official of the Southern Song Dynasty, also known as Chen Rihua as his styled name, was born in Changle, Fuzhou in the reign of Shaoxing, and died during the reign of Duanping. He had been consecutively in the positions of Jiang shi lang (Court Gentleman for Ceremonial Service), Zhi zhou (Prefect) of Lingding, the Ti xing (Judicial Commissioner) of Guangdong, the Zong ling (Overseer-general) of Sichuan, Shan ding (Reviser), Shu lin and other positions in Tongzhou, Yuanzhou. His works included 1 volume of Gu ling xian sheng nian pu (Mr. Guling's Chronological Biography), 1 volume of Tan xie (On Humor), 1 volume of Shi hua (Poetry), 8 volumes of Jin yuan li shu (Jin Yuan's Smart Technique), 3 volumes of Yi jian zhi lei bian (Classified Compilation of Yijian's Annals), (Zeng guang) Suo sui lu (Augmented Records of Trivial Matters), 5 volumes of Jia cang jing yan fang (Family-preserved Empirical Recipes). He also compiled the 8-volume Yin jiang zhi (Yinjiang's Annals), published the 2-volume Jia cang ji yao fang (Collected Essential Recipes from Family Preservation), and other proses and poetry. Jia cang jing yan fang was a formulary compiled by Chen Ye, which was lost. Altogether 74 of its recipes were cited in Fu ren da quan liang fang (Complete Effective Prescriptions for Women's Diseases), Shou qin yang lao shu (A Book for Pursuing Seniors' Longevity and Healthcare), Pu ji fang (Prescriptions for Universal Relief) and Yong le da dian (Yongle Encyclopedia).

Source identification and ecological impact evaluation of PAHs in urban river sediments: A case study in Taiwan.

PubMed

Tu, Y T; Ou, J H; Tsang, D C W; Dong, C D; Chen, C W; Kao, C M

2018-03-01

The Love River and Ho-Jin River, two major urban rivers in Kaohsiung City, Taiwan, are moderately to heavily polluted because different types of improperly treated wastewaters are discharged into the rivers. In this study, sediment and river water samples were collected from two rivers to investigate the river water quality and accumulation of polycyclic aromatic hydrocarbons (PAHs) in sediments. The spatial distribution, composition, and source appointment of PAHs of the sediments were examined. The impacts of PAHs on ecological system were assessed using toxic equivalence quotient (TEQ) of potentially carcinogenic PAHs (TEQ carc ) and sediment quality guidelines. The average PAHs concentrations ranged from 2161 ng/g in Love River sediment to 160 ng/g in Ho-Jin River sediment. This could be due to the fact that Love River Basin had much higher population density and pyrolytic activities. High-ring PAHs (4-6 rings) contributed to 59-90% of the total PAHs concentrations. Benzo(a)pyrene (BaP) had the highest toxic equivalence quotient (up to 188 ng TEQ/g). Moreover, the downstream sediments contained higher TEQ of total TPHs than midstream and upstream sediment samples. The PAHs were adsorbed onto the fine particles with high organic content. Results from diagnostic ratio analyses indicate that the PAHs in two urban river sediments might originate from oil/coal combustion, traffic-related emissions, and waste combustion (pyrogenic activities). Future pollution prevention and management should target the various industries, incinerators, and transportation emission in this region to reduce the PAHs pollution. Copyright © 2017 Elsevier Ltd. All rights reserved.

Identification of hepatic fibroblast growth factor 21 as a mediator in 17β-estradiol-induced white adipose tissue browning.

PubMed

Hua, Lun; Zhuo, Yong; Jiang, Dandan; Li, Jing; Huang, Xiaohua; Zhu, Yingguo; Li, Zhen; Yan, Lijun; Jin, Chao; Jiang, Xuemei; Che, Lianqiang; Fang, Zhengfeng; Lin, Yan; Xu, Shengyu; Li, Jian; Feng, Bin; Wu, De

2018-05-02

Both ovarian E2 and hepatic fibroblast growth factor 21 (FGF21) are critical for energy homeostasis and white adipose tissue browning. Estrogen receptor α (ERα) is abundantly expressed in liver. However, whether FGF21 has a role in E2-induced white adipose tissue browning remains uncertain. In this study, we showed that hepatic Fgf21 expression and secretion during estrus cycle changed with the tetradian oscillatory secretion of circulation E2 in adult, female mice, with their peak expressions and secretions at the proestrus. In addition, exogenous E2 robustly stimulated liver Fgf21 expression and elevated serum FGF21 concentrations, which induced browning gene expression and reduced the tissue weight in subcutaneous white adipose in mice with ovariectomies. The inhibitor of mammalian target of rapamycin (mTOR) and of ERα blocked the induction effect of E2 on the expression of Fgf21 in primary hepatocytes, which revealed that E2 might stimulate FGF21 expression via the ERα-mTOR pathway. Furthermore, FGF21 liver-specific deficiency abolished E2-induced white adipose browning in mice with ovariectomies. This study indicates that ovarian E2 increased liver FGF21 expression directly, which in turn, functioned as an endocrine signal to influence inguinal white adipose tissue browning.-Hua, L., Zhuo, Y., Jiang, D., Li, Jin., Huang, X., Zhu, Y., Li, Z., Yan, L., Jin, C., Jiang, X., Che, L., Fang, Z., Lin, Y., Xu, S. Li, Jia., Feng, B., Wu, D. Identification of hepatic fibroblast growth factor 21 as a mediator in 17β-estradiol-induced white adipose tissue browning.

Transient postnatal fluoxetine leads to decreased brain arachidonic acid metabolism and cytochrome P450 4A in adult mice.

PubMed

Ramadan, Epolia; Blanchard, Helene; Cheon, Yewon; Fox, Meredith A; Chang, Lisa; Chen, Mei; Ma, Kaizong; Rapoport, Stanley I; Basselin, Mireille

2014-05-01

Fetal and perinatal exposure to selective serotonin (5-HT) reuptake inhibitors (SSRIs) has been reported to alter childhood behavior, while transient early exposure in rodents is reported to alter their behavior and decrease brain extracellular 5-HT in adulthood. Since 5-HT2A/2C receptor-mediated neurotransmission can involve G-protein coupled activation of cytosolic phospholipase A2 (cPLA2), releasing arachidonic acid (ARA) from synaptic membrane phospholipid, we hypothesized that transient postnatal exposure to fluoxetine would alter brain ARA metabolism in adult mice. Brain ARA incorporation coefficients k* and rates Jin were quantitatively imaged following intravenous [1-(14)C]ARA infusion of unanesthetized adult mice that had been injected daily with fluoxetine (10mg/kg i.p.) or saline during postnatal days P4-P21. Expression of brain ARA metabolic enzymes and other relevant markers also was measured. On neuroimaging, k* and Jin was decreased widely in early fluoxetine- compared to saline-treated adult mice. Of the enzymes measured, cPLA2 activity was unchanged, while Ca(2+)-independent iPLA2 activity was increased. There was a significant 74% reduced protein level of cytochrome P450 (CYP) 4A, which can convert ARA to 20-HETE. Reduced brain ARA metabolism in adult mice transiently exposed to postnatal fluoxetine, and a 74% reduction in CYP4A protein, suggest long-term effects independent of drug presence in brain ARA metabolism, and in CYP4A metabolites. These changes might contribute to reported altered behavior following early SSRI in rodents. Published by Elsevier Ltd.

Study on the natural and humanistic environment of runcheng town

NASA Astrophysics Data System (ADS)

Huijun, Nie; Jinping, Wang

2018-03-01

Runcheng town is one of the first Chinese characteristic towns to be selected in Shanxi province. It is 38 kilometers from the Jin city and 7 kilometers from Yangcheng County. It’s also an important undertaking place for the project “Industrial Westward Move of Jincheng City” and an important tourist town of Qin Castle Valley. The Runcheng town has a history of thousands of years, with a deep cultural background and unique natural landscape. This paper studies the history and cultural resources and makes a preliminary study on the natural and humanistic environment of the Runcheng town.

Using Computer Vision Techniques to Locate Objects in an Image

DTIC Science & Technology

1988-09-01

Sujata Kakarla J. Wakeley A. S. Maida Snf DTIC SL7CTE0 ;r’!•,,/ )N ATMT~~c.N T" A TICIINICAL REPORT " SR 10 •: 1"R! _ IrIi) The Pennsylvania State...University APPLIED RESEARCH LABORATORY P. 0. Box 30 State College, PA 16804 USING COMPUTER VISION TECHNIQUES TO LOCATE OBJECTS IN AN IMAGE by Sujata Kakarla J...in an Image 12 PERSONAL AUTHOR(S) Sujata Kakarla, J. Wakelev, A. S. Maida 𔃽a TYPE OF REPORT 13b TIME COVERED 14 DATE OF REPORT (Y ar, Month, Day) 5

BATTLE (Biomarker-based Approaches of Targeted Therapy for Lung Cancer Elimination)

DTIC Science & Technology

2011-04-01

bleach- ing. IF microscopy was performed using a Zeiss Axioplan fluorescence  microscope ( Carl  Zeiss Inc.) equipped with a 100-W Hg lamp and narrow...laser scanning microscope ( Carl  Zeiss Inc.) equipped with an argon  laser (458/477/488/514 nm, 30 mW), HeNe laser (413 nm, 1 mW and 633  nm, 5 mW), LSM...Protein-3 (IGFBP-3) in Epithelial IGF-Induced Lung Cancer Development Woo-Young Kim, Mi- Jung Kim,* Hojin Moon,* Ping Yuan, Jin-Soo Kim, Jong-Kyu Woo

New stability conditions for mixed linear Levin-Nohel integro-differential equations

NASA Astrophysics Data System (ADS)

Dung, Nguyen Tien

2013-08-01

For the mixed Levin-Nohel integro-differential equation, we obtain new necessary and sufficient conditions of asymptotic stability. These results improve those obtained by Becker and Burton ["Stability, fixed points and inverse of delays," Proc. - R. Soc. Edinburgh, Sect. A 136, 245-275 (2006)], 10.1017/S0308210500004546 and Jin and Luo ["Stability of an integro-differential equation," Comput. Math. Appl. 57(7), 1080-1088 (2009)], 10.1016/j.camwa.2009.01.006 when b(t) = 0 and supplement the 3/2-stability theorem when a(t, s) = 0. In addition, the case of the equations with several delays is discussed as well.

[Medical exchanges among China and Asiana countries].

PubMed

Chen, H

1996-01-01

Among the issues of medical exchanges, medicaments are more often encountered than medical issues, based on ancient Chinese literatures, early in the Han-Jin Dynasties, Thailand, Malaysia, Indonesia, and Brunei had exchanges with China, also in Sui-Tang Dynasties. In the Song-Yuan Dynasties, ancient Singapore and the Philippines also incorporated in exchanges of medicament and goods. In the Ming-Qing dynasties, these 6 Asian countries had even more close contact with China, especially in trades and medical exchanges among the masses, carried out in a large scale thus, promoting the advent and development of TCM in Asiana Regions.

Comparative transcriptome profiling of Pyropia yezoensis (Ueda) M.S. Hwang & H.G. Choi in response to temperature stresses.

PubMed

Sun, Peipei; Mao, Yunxiang; Li, Guiyang; Cao, Min; Kong, Fanna; Wang, Li; Bi, Guiqi

2015-06-17

Pyropia yezoensis is a model organism often used to investigate the mechanisms underlying stress tolerance in intertidal zones. The digital gene expression (DGE) approach was used to characterize a genome-wide comparative analysis of differentially expressed genes (DEGs) that influence the physiological, developmental or biochemical processes in samples subjected to 4 treatments: high-temperature stress (HT), chilling stress (CS), freezing stress (FS) and normal temperature (NT). Equal amounts of total RNAs collected from 8 samples (two biological replicates per treatment) were sequenced using the Illumina/Solexa platform. Compared with NT, a total of 2202, 1334 and 592 differentially expressed unigenes were detected in HT, CS and FS respectively. Clustering analysis suggested P. yezoensis acclimates to low and high-temperature stress condition using different mechanisms: In heat stress, the unigenes related to replication and repair of DNA and protein processing in endoplasmic reticulum were active; however at low temperature stresses, unigenes related to carbohydrate metabolism and energy metabolism were active. Analysis of gene differential expression showed that four categories of DEGs functioning as temperature sensors were found, including heat shock proteins, H2A, histone deacetylase complex and transcription factors. Heat stress caused chloroplast genes down-regulated and unigenes encoding metacaspases up-regulated, which is an important regulator of PCD. Cold stress caused an increase in the expression of FAD to improve the proportion of polyunsaturated fatty acids. An up-regulated unigene encoding farnesyl pyrophosphate synthase was found in cold stress, indicating that the plant hormone ABA also played an important role in responding to temperature stress in P. yezoensis. The variation of amount of unigenes and different gene expression pattern under different temperature stresses indicated the complicated and diverse regulation mechanism in response to temperature stress in P. yezoensis. Several common metabolism pathways were found both in P. yezoensis and in higher plants, such as FAD in low-temperature stress and HSP in heat stress. Meanwhile, many chloroplast genes and unigene related to the synthesis of abscisic acid were detected, revealing its unique temperature-regulation mechanism in this intertidal species. This sequencing dataset and analysis may serve as a valuable resource to study the mechanisms involved in abiotic stress tolerance in intertidal seaweeds.

PM2.5 Pollution in China and How It Has Been Exacerbated by Terrain and Meteorological Conditions

NASA Astrophysics Data System (ADS)

Wang, K.; Wang, X., , Dr; Dickinson, R. E.; Su, L.; Zhou, C.

2017-12-01

The recent severe and frequent PM2.5 (i.e., fine particles smaller than 2.5 μm) pollution in China has aroused unprecedented public concern. The first two-years of PM2.5 measurements in China are reported and compared with those of Europe and the U.S. The average PM2.5 concentration in China is approximately five times of that over Europe and America. The contribution of atmospheric dispersion to such air quality is evaluated in this study. Air stagnation or its absence is a good indicator of the atmosphere's capability to disperse its pollutants, but the NOAA definition of an air stagnation event is found to not be applicable to China since it depends on vertical mixing that is weakened in China by the effects of terrain. To address this deficiency, a new threshold for air stagnation events is proposed that depends on the 10 m wind speed, boundary layer height and occurrence of precipitation. This new defined air stagnation closely tracks the day-to-day variation of PM2.5 concentrations. Such events are more frequent over China than over Europe and the U.S during autumn and winter, especially over the Sichuan Basin and Jing-Jin-Ji region of China. If China had the same frequency of air stagnation as the U.S or Europe, 67% and 82% of its stations would improve their current air quality during autumn and winter, e.g., an average of 12% decrease in PM2.5 concentrations for Jing-Jin-Ji region in wintertime. Its severe pollution and frequent air stagnation conditions make controls on emission less effective in China than elsewhere.

Research on Xi Jinping's Thought of Ecological Civilization and Environment Sustainable Development

NASA Astrophysics Data System (ADS)

Xiang-chao, Pan

2018-05-01

Since the reform and opening up, China’s sustained and rapid economic development, but the environment problem increasingly is prominent in our country. It has seriously affected the sustainability of economic development in China. Environment overall situation is not optimistic, and environmental management is imperative. Since the 18th national congress of the Communist Party of China (CPC), Xi Jin-ping has put forward the thought of building a beautiful China with ecological civilization and realizing the sustainable development of economic construction and environmental protection. Sticking to Xi's Thought of Ecological Civilization is a fundamental guarantee for the sustainable development of environment and building a new era of ecological civilization.

Convenient, sensitive and high-throughput method for screening botanic origin.

PubMed

Yuan, Yuan; Jiang, Chao; Liu, Libing; Yu, Shulin; Cui, Zhanhu; Chen, Min; Lin, Shufang; Wang, Shu; Huang, Luqi

2014-06-23

In this work, a rapid (within 4-5 h), sensitive and visible new method for assessing botanic origin is developed by combining loop-mediated isothermal amplification with cationic conjugated polymers. The two Chinese medicinal materials (Jin-Yin-Hua and Shan-Yin-Hua) with similar morphology and chemical composition were clearly distinguished by gene SNP genotyping assays. The identification of plant species in Patented Chinese drugs containing Lonicera buds is successfully performed using this detection system. The method is also robust enough to be used in high-throughput screening. This new method is very helpful to identify herbal materials, and is beneficial for detecting safety and quality of botanic products.

[Analysis on origin and evolution of mumps].

PubMed

Zhao, Yan

2004-10-01

There was a preliminary recognition on mumps during the Qin-Han to Sui-Tang dynasty, laying a foundation for the scholastic development on this topic in later generations. The title of this disease was identified in Song-Jin-Yuan dynasty with gradual deepening on its principle-method-formula-medication system, a great progress of recognition as compared with the previous ages. In the Ming-Qing dynasty, the recognition became even more systematic, with certain breakthrough in the system of principle-method-formula-medication. In modern age, the experiences were inherited and developed to integrate to modern biomedicine, so that the theory and clinical practice become even more perfect.

Linear Magnetochiral effect in Weyl Semimetals

NASA Astrophysics Data System (ADS)

Cortijo, Alberto

We describe the presence of a linear magnetochiral effect in time reversal breaking Weyl semimetals. The magnetochiral effect consists in a simultaneous linear dependence of the magnetotransport coefficients with the magnetic field and a momentum vector. This simultaneous dependence is allowed by the Onsager reciprocity relations, being the separation vector between the Weyl nodes the vector that plays such role. This linear magnetochiral effect constitutes a new transport effect associated to the topological structures linked to time reversal breaking Weyl semimetals. European Union structural funds and the Comunidad de Madrid MAD2D-CM Program (S2013/MIT-3007) and MINECO (Spain) Grant No. FIS2015-73454-JIN.

The Production of the AGARD Multilingual Aeronautical Dictionary Using Computer Techniques,

DTIC Science & Technology

1981-04-01

INl 10161 AnfliigknapuN if) 1 6877 Abatugalau (t) 10068 Ahkjntut, . fiI 10642 Anftigkannolfea (I1867 Ah.ug nng ft) 10062 skususocl, Aussabiohung 111...jA jin00 I.... (. . 167 ipndn I10063 ni-- M--1 M 13632 dAjinn!,-O In -1611’nn .*,.oIi P67 ,n . , 10062 d..-0a~ 1-014~~ /V *A 10064 .. n.lj If).t~ 1016...oilnn~nnn (0621 I) 10062 dnp4In.,l*tI0q 18891 aalln’." I/) IWAn.,0I 104s 16 0 ......nln In) )-d/ IVAann.. 14606 ipinO n W66 eggs~ l d n/njf l (If) d~p

Convenient, Sensitive and High-Throughput Method for Screening Botanic Origin

NASA Astrophysics Data System (ADS)

Yuan, Yuan; Jiang, Chao; Liu, Libing; Yu, Shulin; Cui, Zhanhu; Chen, Min; Lin, Shufang; Wang, Shu; Huang, Luqi

2014-06-01

In this work, a rapid (within 4-5 h), sensitive and visible new method for assessing botanic origin is developed by combining loop-mediated isothermal amplification with cationic conjugated polymers. The two Chinese medicinal materials (Jin-Yin-Hua and Shan-Yin-Hua) with similar morphology and chemical composition were clearly distinguished by gene SNP genotyping assays. The identification of plant species in Patented Chinese drugs containing Lonicera buds is successfully performed using this detection system. The method is also robust enough to be used in high-throughput screening. This new method is very helpful to identify herbal materials, and is beneficial for detecting safety and quality of botanic products.

Effects of a natural sepiolite bearing material and lime on the immobilization and persistence of cadmium in a contaminated acid agricultural soil.

PubMed

Cao, Xueying; Hu, Pengjie; Tan, Changyin; Wu, Longhua; Peng, Bo; Christie, Peter; Luo, Yongming

2018-05-25

Soil contamination with cadmium (Cd) represents a substantial threat to human health and environmental quality. Long-term effectiveness and persistence of remediation are two important criteria for the evaluation of amendment techniques used to remediate soils polluted with potentially toxic metals. In the current study, we investigated the remediation persistence of a natural sepiolite bearing material (NSBM, containing 15% sepiolite) and ground limestone (equivalent to > 98.0% CaO) on soil pH, Cd bioavailability, and Cd accumulation by pak choi (Brassica chinensis L.) during the growth of four consecutive crops in a Cd-contaminated acid soil with different amounts of NSBM (0, 0.2, 0.5, 1, 2, and 5%). Soil pH levels ranged from 5.21 to 7.76 during the first crop, 4.30 to 7.34 during the second, 4.23 to 7.80 during the third, and 4.33 to 6.98 during the fourth, and increased significantly with increasing the application rate of NSBM. Soil CaCl 2 -Cd and shoot Cd concentrations decreased by 8.11 to 99.2% and 6.58 to 94.5%, respectively, compared with the control throughout the four cropping seasons. A significant negative correlation was found between soil CaCl 2 -Cd and soil pH. Combined use of 0.1% lime and NSBM showed greater effects than NSBM alone, especially, when the application rate of NSBM was ˂ 2%. Moreover, pak choi tissue Cd concentrations in the treatments with NSBM addition alone at ≥ 2% or at ≥ 1% NSBM combined with 0.1% lime met the maximum permissible concentration (MPC) over the four crops, allowed by the Chinese and European regulations. Based on the present study, safe crop production in the test soil is possible at a soil pH > 6.38 and CaCl 2 -Cd < 14 μg kg -1 , and soil Cd immobilization by NSBM without or with lime is a potentially feasible method of controlling the transfer of soil Cd into the food chain.

Why not procrastinate? Development and validation of a new active procrastination scale.

PubMed

Choi, Jin Nam; Moran, Sarah V

2009-04-01

Procrastination has been studied as a dysfunctional, self-effacing behavior that ultimately results in undesirable outcomes. However, A. H. C. Chu and J. N. Choi (2005) found a different form of procrastination (i.e., active procrastination) that leads to desirable outcomes. The construct of active procrastination has a high potential to expand the time management literature and is likely to be adopted by researchers in multiple areas of psychology. To facilitate the research on this new construct and its further integration into the literature, the authors developed and validated a new, expanded measure of active procrastination that reliably assesses its four dimensions. Using this new measure of active procrastination, they further examined its nomological network. The new 16-item measure is a critical step toward further empirical investigation of active procrastination.

Anti-resonance scattering at defect levels in the quantum conductance of a one-dimensional system

NASA Astrophysics Data System (ADS)

Sun, Z. Z.; Wang, Y. P.; Wang, X. R.

2002-03-01

For the ballistic quantum transport, the conductance of one channel is quantized to a value of 2e^2/h described by the Landauer formula. In the presence of defects, electrons will be scattered by these defects. Thus the conductance will deviate from the values of the quantized conductance. We show that an anti-resonance scattering can occur when an extra defect level is introduced into a conduction band. At the anti-resonance scattering, exact one quantum conductance is destroyed. The conductance takes a non-zero value when the Fermi energy is away from the anti-resonance scattering. The result is consistent with recent numerical calculations given by H. J. Choi et al. (Phys. Rev. Lett. 84, 2917(2000)) and P. L. McEuen et al. (Phys. Rev. Lett. 83, 5098(1999)).

Linear Combination Fitting (LCF)-XANES analysis of As speciation in selected mine-impacted materials

EPA Pesticide Factsheets

This table provides sample identification labels and classification of sample type (tailings, calcinated, grey slime). For each sample, total arsenic and iron concentrations determined by acid digestion and ICP analysis are provided along with arsenic in-vitro bioaccessibility (As IVBA) values to estimate arsenic risk. Lastly, the table provides linear combination fitting results from synchrotron XANES analysis showing the distribution of arsenic speciation phases present in each sample along with fitting error (R-factor).This dataset is associated with the following publication:Ollson, C., E. Smith, K. Scheckel, A. Betts, and A. Juhasz. Assessment of arsenic speciation and bioaccessibility in mine-impacted materials. Diana Aga, Wonyong Choi, Andrew Daugulis, Gianluca Li Puma, Gerasimos Lyberatos, and Joo Hwa Tay JOURNAL OF HAZARDOUS MATERIALS. Elsevier Science Ltd, New York, NY, USA, 313: 130-137, (2016).

Chronic coexistence of two troponin T isoforms in adult transgenic mouse cardiomyocytes decreased contractile kinetics and caused dilatative remodeling

PubMed Central

Yu, Zhi-Bin; Wei, Hongguang

2012-01-01

Our previous in vivo and ex vivo studies suggested that coexistence of two or more troponin T (TnT) isoforms in adult cardiac muscle decreased cardiac function and efficiency (Huang QQ, Feng HZ, Liu J, Du J, Stull LB, Moravec CS, Huang X, Jin JP, Am J Physiol Cell Physiol 294: C213–C22, 2008; Feng HZ, Jin JP, Am J Physiol Heart Circ Physiol 299: H97–H105, 2010). Here we characterized Ca2+-regulated contractility of isolated adult cardiomyocytes from transgenic mice coexpressing a fast skeletal muscle TnT together with the endogenous cardiac TnT. Without the influence of extracellular matrix, coexistence of the two TnT isoforms resulted in lower shortening amplitude, slower shortening and relengthening velocities, and longer relengthening time. The level of resting cytosolic Ca2+ was unchanged, but the peak Ca2+ transient was lowered and the durations of Ca2+ rising and decaying were longer in the transgenic mouse cardiomyocytes vs. the wild-type controls. Isoproterenol treatment diminished the differences in shortening amplitude and shortening and relengthening velocities, whereas the prolonged durations of relengthening and Ca2+ transient in the transgenic cardiomyocytes remained. At rigor state, a result from depletion of Ca2+, resting sarcomere length of the transgenic cardiomyocytes became shorter than that in wild-type cells. Inhibition of myosin motor diminished this effect of TnT function on cross bridges. The length but not width of transgenic cardiomyocytes was significantly increased compared with the wild-type controls, corresponding to longitudinal addition of sarcomeres and dilatative remodeling at the cellular level. These dominantly negative effects of normal fast TnT demonstrated that chronic coexistence of functionally distinct variants of TnT in adult cardiomyocytes reduces contractile performance with pathological consequences. PMID:22538236

Identification of the Low-velocity Zone Beneath the Northern Taiwan by the P-wave Delays Analysis

NASA Astrophysics Data System (ADS)

Chang, C. W.; Che-Min, L.

2017-12-01

Taipei City, the capital of Taiwan, located in northern Taiwan is near to the Tatun volcano group and the Shanchiao fault which is an active fault. This region is a complex tectonic environment. The Tatun volcano group is seen as a dormant volcano. Recently, the location of the magma reservoir of the Tatun volcano was discussed again. However, the volume and the location of the magma reservoir are still unclear. There are several seismic networks operated by different institutions around Taipei and Tatun volcano. In this study, we combined the data of these networks to analysis the P-wave arrival times for clarifying the magma reservoir. The events with hypocenters are deeper than 100 km and the local magnitude (ML) are larger than 4.0 were collected to analysis. Our results show that the stations could be separated into three groups by the slope of the P-wave arrival time. They are distributed at the western of the Basin edge, the Jin-Shan Plain areal and the Taipei Basin, respectively. When the epicenter distance of the different stations is the same, the P-wave arrival time of the stations on the west side of the basin edge will be 0.3 0.5 seconds later than that in the Taipei Basin, and the stations on the Jin-Shan Plain will be 0.1 0.4 seconds later than in the Taipei Basin. The slope of the P-wave arrival time in 3 groups is very different, indicating that the low-velocity zone is existed in shallow crustal beneath of these areas. However, the low-velocity zone can be connected to the magma reservoir of the Tatun volcano group or submarine volcano of Keelung Island or not? It can be discussed the correlation between the magma reservoir and the low-velocity zone by more events collected.

Evidence for Environmental Dissemination of Antibiotic Resistance Mediated by Wild Birds.

PubMed

Wu, Jiao; Huang, Ye; Rao, Dawei; Zhang, Yongkui; Yang, Kun

2018-01-01

The aquatic bird, egret, could carry antibiotic resistance (AR) from a contaminated waterway (Jin River, Chengdu, China) into the surrounding environment (Wangjianglou Park). A systematic study was carried out on the unique environmental dissemination mode of AR mediated by birds. The minimum inhibitory concentrations of various antibiotics against the environmental Escherichia coli isolates were used to evaluate the bacterial AR at the environmental locations where these isolates were recovered, i.e., the Jin River water, the egret feces, the park soil, and the campus soil. The level of AR in the park soil was significantly higher than that in the campus soil that was seldom affected by the egrets, which suggested that the egrets mediated the transportation of AR from the polluted waterway to the park. Genotyping of the resistant E. coli isolates via repetitive-element PCR gave no strong correlation between the genotypes and the AR patterns of the bacteria. So, the transfer of resistant strains should not be the main mode of AR transportation in this process. The results of real-time PCR revealed that the abundance of antibiotic resistance genes (ARGs) and mobile genetic element (MGE) sequences (transposase and integrase genes) declined along the putative transportation route. The transportation of ARGs could be due to their linkage with MGE sequences, and horizontal gene transfer should have contributed to the process. The movable colistin-resistance gene mcr-1 was detected among the colistin-resistant E. coli strains isolated from the river water and the egret feces, which indicated the possibility of the environmental dissemination of this gene. Birds, especially the migratory birds, for the role they played on the dissemination of environmental AR, should be considered when studying the ecology of AR.

New PDLC materials obtained from dispersion of LC under microgravity

NASA Astrophysics Data System (ADS)

Matos, M. R.; Leitao, J. C.; Andre, R. M.; Zambujal, R.; Carmelo Rosa, Carla; Simeao Carvalho, P.; Podgorski, Thomas

Aknowledgements: This project has been supported by ESA-Education, the University of Porto, IFIMUP and INESC-Porto. Bibliography: [1] F Bloisi and L Vicari. Optical Applications of Liquid Crystals, chapter 4: Polymer-dispersed liquid crystals. Institute of Physics Publishing, 2003. [2] J. William Doane. Liquid Crystals Applications and Uses, volume 1, chapter 14: Polymer Dispersed Liquid Crystal Displays, pages 361-391. World Scientific, 1990. [3] K. Parbhakar, J. M. Jin, H. M. Nguyen, and L. H. Dao. Effect of microgravity on the distribution of liquid-crystal droplets dispersed in a polymer matrix. CHEMISTRY OF MA-TERIALS, 8(??):1210-1216, Jun 1996. [4] Paul S. Drzaic. Liquid Crystal Dispersions, volume 1. World Scientific, 1995.

Magnetoassociation of KRb Feshbach molecules

NASA Astrophysics Data System (ADS)

Cumby, Tyler; Perreault, John; Shewmon, Ruth; Jin, Deborah

2010-03-01

I will discuss experiments in which we study the creation of ^40K^87Rb Feshbach molecules via magnetoassociation. We measure the molecule number as a function of the magnetic-field sweep rate through the interspecies Feshbach resonance and explore the dependence of association on the initial atom gas conditions. This study of the Feshbach molecule creation process may be relevant to the production of ultracold polar molecules, where magnetoassociated Feshbach molecules can be a crucial first step [1].[4pt] [1] K.-K. Ni, S. Ospelkaus, M. H. G. de Miranda, A. Peer, B. Neyenhuis, J. J. Zirbel, S. Kotochigova, P. S. Julienne, D. S. Jin, and J. Ye, Science, 2008, 322, 231- 235.

Magnetoassociation of KRb Feshbach molecules

NASA Astrophysics Data System (ADS)

Cumby, Tyler; Perreault, John; Shewmon, Ruth; Jin, Deborah

2010-03-01

I will discuss experiments in which we study the creation of ^40K^87Rb Feshbach molecules via magnetoassociation. We measure the molecule number as a function of the magnetic-field sweep rate through the interspecies Feshbach resonance and explore the dependence of association on the initial atom gas conditions. This study of the Feshbach molecule creation process may be relevant to the production of ultracold polar molecules, where magnetoassociated Feshbach molecules can be a crucial first step [1].[4pt] [1] K.-K. Ni, S. Ospelkaus, M. H. G. de Miranda, A. Peer, B. Neyenhuis, J. J. Zirbel, S. Kotochigova, P. S. Julienne, D. S. Jin, and J. Ye, Science, 2008, 322, 231-235.

Research on the performance evaluation of agricultural products supply chain integrated operation

NASA Astrophysics Data System (ADS)

Jiang, Jiake; Wang, Xifu; Liu, Yang

2017-04-01

The agricultural product supply chain integrated operation can ensure the quality and efficiency of agricultural products, and achieve the optimal goal of low cost and high service. This paper establishes a performance evaluation index system of agricultural products supply chain integration operation based on the development status of agricultural products and SCOR, BSC and KPI model. And then, we constructing rough set theory and BP neural network comprehensive evaluation model with the aid of Rosetta and MATLAB tools and the case study is about the development of agricultural products integrated supply chain in Jing-Jin-Ji region. And finally, we obtain the corresponding performance results, and give some improvement measures and management recommendations to the managers.

IFSSH Flexor Tendon Committee report 2014: from the IFSSH Flexor Tendon Committee (Chairman: Jin Bo Tang).

PubMed

Tang, Jin Bo; Chang, James; Elliot, David; Lalonde, Donald H; Sandow, Michael; Vögelin, Esther

2014-01-01

Hand surgeons continue to search for the best surgical flexor tendon repair and treatment of the tendon sheaths and pulleys, and they are attempting to establish postoperative regimens that fit diverse clinical needs. It is the purpose of this report to present the current views, methods, and suggestions of six senior hand surgeons from six different countries - all experienced in tendon repair and reconstruction. Although certainly there is common ground, the report presents provocative views and approaches. The report reflects an update in the views of the committee. We hope that it is helpful to surgeons and therapists in treating flexor tendon injuries.

Recent progress in the use of ‘omics technologies in brassicaceous vegetables

PubMed Central

Witzel, Katja; Neugart, Susanne; Ruppel, Silke; Schreiner, Monika; Wiesner, Melanie; Baldermann, Susanne

2015-01-01

Continuing advances in ‘omics methodologies and instrumentation is enhancing the understanding of how plants cope with the dynamic nature of their growing environment. ‘Omics platforms have been only recently extended to cover horticultural crop species. Many of the most widely cultivated vegetable crops belong to the genus Brassica: these include plants grown for their root (turnip, rutabaga/swede), their swollen stem base (kohlrabi), their leaves (cabbage, kale, pak choi) and their inflorescence (cauliflower, broccoli). Characterization at the genome, transcript, protein and metabolite levels has illustrated the complexity of the cellular response to a whole series of environmental stresses, including nutrient deficiency, pathogen attack, heavy metal toxicity, cold acclimation, and excessive and sub-optimal irradiation. This review covers recent applications of ‘omics technologies to the brassicaceous vegetables, and discusses future scenarios in achieving improvements in crop end-use quality. PMID:25926843

Re: Penetration Behavior of Opposed Rows of Staggered Secondary Air Jets Depending on Jet Penetration Coefficient and Momentum Flux Ratio

NASA Technical Reports Server (NTRS)

Holdeman, James D.

2016-01-01

The purpose of this article is to explain why the extension of the previously published C = (S/Ho)sqrt(J) scaling for opposed rows of staggered jets wasn't directly successful in the study by Choi et al. (2016). It is not surprising that staggered jets from opposite sides do not pass each other at the expected C value, because Ho/D and sqrt(J) are much larger than the maximum in previous studies. These, and large x/D's, tend to suggest development of 2-dimensional flow. Although there are distinct optima for opposed rows of in-line jets, single-side injection, and opposed rows of staggered jets based on C, opposed rows of staggered jets provide as good or better mixing performance, at any C value, than opposed rows of in-line jets or jets from single-side injection.

A realization of sound focused personal audio system using acoustic contrast control.

PubMed

Chang, Ji-Ho; Lee, Chan-Hui; Park, Jin-Young; Kim, Yang-Hann

2009-04-01

A personal audio system that does not use earphone or any wire would have great interest and potential impact on the audio industries. In this study, a line array speaker system is used to localize sound in the listening zone. The contrast control [Choi, J.-W. and Kim, Y.-H. (2002). J. Acoust. Soc. Am. 111, 1695-1700] is applied, which is a method to make acoustically bright zone around the user and acoustically dark zone in other regions by maximizing the ratio of acoustic potential energy density between the bright and the dark zone. This ratio is regarded as acoustic contrast, analogous with what is used for optical devices. For the evaluation of the performance of acoustic contrast control, experiments are performed and the results are compared with those of uncontrolled case and time reversal array.

Preface

NASA Astrophysics Data System (ADS)

Sarusi, Gabby; Gunapala, Sarath D.

2017-08-01

This special issue of Journal of Infrared Physics and Technology is brought to you following an international conference on Quantum Structure Infrared Photodetector (QSIP) that took place on June 2016 in Tel-Aviv, Israel, called QSIP2016. During QSIP2016 conference we had the honor to host Dr. Barry F. Levine that was the pioneer in this field since the 80s at AT&T Bell Labs working on quantum wells infrared photodetectors (QWIPs). Luckily, four of his former post-docs (Choi, Gunapala, Bandara and Sarusi) are still working in this field and they took a major part in contributing the QSIP2016 conference. All papers presented in this special issue went through the highest standard peer-review process of Journal of Infrared Physics and Technology, where 15 papers were reached the final stage and accepted for publication.

The effectiveness of traditional Chinese medicine-based lifestyle interventions on biomedical, psychosocial, and behavioral outcomes in individuals with type 2 diabetes: A systematic review with meta-analysis.

PubMed

Yu, Xingfeng; Chau, Janita P C; Huo, Lanting

2018-04-01

Integrative diabetes care, which combines conventional diabetes therapy with traditional Chinese medicine (TCM)-based interventions, has gained popularity worldwide. Numerous TCM-based lifestyle modification approaches have been proposed for individuals with type 2 diabetes (T2DM). To synthesize and present the best available evidence on the effectiveness of TCM-based lifestyle interventions in individuals with T2DM. We undertook a systematic review of randomized controlled trials or controlled clinical trials. Six English and four Chinese electronic databases were searched from their inceptions to December 2016. Trials investigating the effectiveness of various TCM-based lifestyle interventions among adults with T2DM were reviewed. Studies were excluded if TCM-based lifestyle interventions were only part of the intervention regimen. Two reviewers independently selected studies according to pre-specified inclusion and exclusion criteria and appraised the risk of bias of the included studies. One reviewer extracted details of the included studies and the second reviewer checked the extracted data critically. When feasible, data were statistically pooled for meta-analysis. Otherwise, narrative summaries were used. Twenty-four studies were included. The pooled analysis of the eight studies on tai chi showed tai chi practice for at least 150 min per week was beneficial in lowering glycosylated hemoglobin (mean difference, -1.48%; 95%CI, -2.58% to -0.39%; p < 0.001). Tai chi was effective in reducing fasting blood glucose (mean difference, -1.14 mmol/L; 95%CI, -1.78 to -0.50 mmol/L; p < 0.001) and body mass index (mean difference, -0.62; 95%CI, -1.14 to -0.11; p = 0.02), and improving quality of life. The effects of tai chi on blood pressure and waist circumference were inconclusive due to the limited number of studies. The meta-analysis of the 12 studies on ba duan jin demonstrated beneficial effects on glycosylated hemoglobin (mean difference, -0

IS THE LINE-LIKE OPTICAL AFTERGLOW SED OF GRB 050709 DUE TO A FLARE?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liu, Cong; Jin, Zhi-Ping; Wei, Da-Ming, E-mail: jin@pmo.ac.cn

Recently, Jin et al. reanalyzed the optical observation data of GRB 050709 and reported a line-like spectral energy distribution (SED) component observed by the Very Large Telescope at t  ∼ 2.5 days after the trigger of the burst, which had been interpreted as a broadened line signal arising from a macronova dominated by an iron group. In this work, we show that an optical flare origin of such a peculiar optical SED is still possible. Interestingly, even in such a model, an “unusual” origin of the late-time long-lasting Hubble Space Telescope F 814 W -band emission is still needed and a macronova/kilonovamore » is the natural interpretation.« less

Genome-wide analysis of coordinated transcript abundance during seed development in different Brassica rapa morphotypes.

PubMed

Basnet, Ram Kumar; Moreno-Pachon, Natalia; Lin, Ke; Bucher, Johan; Visser, Richard G F; Maliepaard, Chris; Bonnema, Guusje

2013-12-01

Brassica seeds are important as basic units of plant growth and sources of vegetable oil. Seed development is regulated by many dynamic metabolic processes controlled by complex networks of spatially and temporally expressed genes. We conducted a global microarray gene co-expression analysis by measuring transcript abundance of developing seeds from two diverse B. rapa morphotypes: a pak choi (leafy-type) and a yellow sarson (oil-type), and two of their doubled haploid (DH) progenies, (1) to study the timing of metabolic processes in developing seeds, (2) to explore the major transcriptional differences in developing seeds of the two morphotypes, and (3) to identify the optimum stage for a genetical genomics study in B. rapa seed. Seed developmental stages were similar in developing seeds of pak choi and yellow sarson of B. rapa; however, the colour of embryo and seed coat differed among these two morphotypes. In this study, most transcriptional changes occurred between 25 and 35 DAP, which shows that the timing of seed developmental processes in B. rapa is at later developmental stages than in the related species B. napus. Using a Weighted Gene Co-expression Network Analysis (WGCNA), we identified 47 "gene modules", of which 27 showed a significant association with temporal and/or genotypic variation. An additional hierarchical cluster analysis identified broad spectra of gene expression patterns during seed development. The predominant variation in gene expression was according to developmental stages rather than morphotype differences. Since lipids are the major storage compounds of Brassica seeds, we investigated in more detail the regulation of lipid metabolism. Four co-regulated gene clusters were identified with 17 putative cis-regulatory elements predicted in their 1000 bp upstream region, either specific or common to different lipid metabolic pathways. This is the first study of genome-wide profiling of transcript abundance during seed development in B

Development of remote sensing techniques for assessment of salinity induced plant stresses

NASA Astrophysics Data System (ADS)

Stong, Matthew Harold

Salinity has been shown to reduce vegetative growth, crop quality, and yield in agricultural crops. Remote sensing is capable of providing data about large areas. This project was designed to induce salinity stress in a crop, pak choi, and thereafter monitor the response of the crop as expressed by its spectral reflectances. The project was conducted in the National Taiwan University Phytotron, and spectral data was collected using a GER 2600. Yield and soil salinity (ECe) were also measured. After three seasons of data were collected, wavelengths sensitive to salinity were selected. These wavelengths, which are within the spectral response of biochemicals produced by plants as a response to soil salinity, were used to create two indices, the Salinity Stress Index (SSI) and the Normalized Salinity Stress Index (NSSI). After creating the indices tests were conducted to determine the efficacy of these indices in detecting salinity and drought stresses as compared to existing indices (SRVI and NDVI). This project induced salinity and drought stress in a crop, pak choi, and thereafter monitored the response of the crop as expressed by its spectral reflectances. The SSI and NSSI correlated well to both ECe and marketable yield. Additionally the SSI and NSSI were found to provide statistical differences between salinity stressed treatments and the control treatment. Drought stress was not detected well by any of the indices reviewed although the SSI and NSSI indices tended to increase with drought stress and decrease with salinity stress. As a final test, specific ion toxicities of sodium and chloride were tested against the developed indices (SSI and NSSI) and existing indices (NDVI, SRVI, and NDWI). There were no differences in SSI and NSSI responses to specific ion concentration in the high salinity treatments. These results indicated that the SSI and NSSI are not sensitive to the specific ion concentration in irrigation water. However, the SSI and NSSI were higher

Generically large nongaussianity in small multifield inflation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bramante, Joseph

If forthcoming measurements of cosmic photon polarization restrict the primordial tensor-to-scalar ratio to r<0.01, small field inflation will be a principal candidate for the origin of the universe. Here we show that small multifield inflation, without the hybrid mechanism, typically results in large squeezed nongaussianity. Small multifield potentials contain multiple flat field directions, often identified with the gauge invariant field directions in supersymmetric potentials. We find that unless these field directions have equal slopes, large nongaussianity arises. After identifying relevant differences between large and small two-field potentials, we demonstrate that the latter naturally fulfill the Byrnes-Choi-Hall large nongaussianity conditions. Computationsmore » of the primordial power spectrum, spectral index, and squeezed bispectrum, reveal that small two-field models which otherwise match observed primordial perturbations, produce excludably large nongaussianity if the inflatons’ field directions have unequal slopes.« less

Generically large nongaussianity in small multifield inflation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bramante, Joseph, E-mail: josephbramante@gmail.com

If forthcoming measurements of cosmic photon polarization restrict the primordial tensor-to-scalar ratio to r < 0.01, small field inflation will be a principal candidate for the origin of the universe. Here we show that small multifield inflation, without the hybrid mechanism, typically results in large squeezed nongaussianity. Small multifield potentials contain multiple flat field directions, often identified with the gauge invariant field directions in supersymmetric potentials. We find that unless these field directions have equal slopes, large nongaussianity arises. After identifying relevant differences between large and small two-field potentials, we demonstrate that the latter naturally fulfill the Byrnes-Choi-Hall large nongaussianity conditions. Computationsmore » of the primordial power spectrum, spectral index, and squeezed bispectrum, reveal that small two-field models which otherwise match observed primordial perturbations, produce excludably large nongaussianity if the inflatons' field directions have unequal slopes.« less

Metabolic engineering of microorganisms for the production of higher alcohols.

PubMed

Choi, Yong Jun; Lee, Joungmin; Jang, Yu-Sin; Lee, Sang Yup

2014-09-02

Due to the increasing concerns about limited fossil resources and environmental problems, there has been much interest in developing biofuels from renewable biomass. Ethanol is currently used as a major biofuel, as it can be easily produced by existing fermentation technology, but it is not the best biofuel due to its low energy density, high vapor pressure, hygroscopy, and incompatibility with current infrastructure. Higher alcohols, including 1-propanol, 1-butanol, isobutanol, 2-methyl-1-butanol, and 3-methyl-1-butanol, which possess fuel properties more similar to those of petroleum-based fuel, have attracted particular interest as alternatives to ethanol. Since microorganisms isolated from nature do not allow production of these alcohols at high enough efficiencies, metabolic engineering has been employed to enhance their production. Here, we review recent advances in metabolic engineering of microorganisms for the production of higher alcohols. Copyright © 2014 Choi et al.

Factors affecting THMs, HAAs and HNMs formation of Jin Lan Reservoir water exposed to chlorine and monochloramine.

PubMed

Hong, Huachang; Xiong, Yujing; Ruan, Mengyong; Liao, Fanglei; Lin, Hongjun; Liang, Yan

2013-02-01

The formations of THMs, HAAs, and HNMs from chlorination and chloramination of water from Jinlan Reservoir were investigated in this study. Results showed that monochloramine rather than chlorine generally resulted in lower concentration of DBPs, and the DBPs formation varied greatly as the treatment conditions changed. Specifically, the yields of THMs, HAAs and HNMs all increased with the high bromide level and high disinfectant dose both during chlorination and chloramination. The longer reaction time had a positive effect on the formation of THMs, HAAs and HNMs during chlorination and HNMs during chloramination. However, no time effect was observed on the formation of THMs and HAAs during chloramination. An increase in pH enhanced the levels of THMs and HNMs upon chlorination but reduced levels of HNMs upon chloramination. As for the THMs in chloramination and HAAs in chlorination and chloramination, no obvious pH effect was observed. The elevated temperature significantly increased the yields of THMs during chlorination and HNMs during chloramination, but has no effect on THMs and HAAs yields during chloramination. In the same temperature range, the formation of HAAs and HNMs in chlorination showed a first increasing and then a decreasing trend. In chloramination study, addition of nitrite markedly increased the formation of HNMs but had little impact on the formation of THMs and HAAs. While in chlorination study, the presence of high nitrite levels significantly reduced the yields of THMs, HAAs and HNMs. Range analysis revealed that the bromide and disinfectant levels were the major factors affecting THMs, HAAs and HNMs formation, in both chlorination and chloramination. Finally, comparisons of the speciation of mono-halogenated, di-halogenated, tri-halogenated HAAs and HNMs between chlorination and monochloramination were also conducted, and factors influencing the speciation pattern were identified. Copyright © 2012 Elsevier B.V. All rights reserved.

Unlocking Ft: Modeling thermodynamic controls and isotope fractionation factors in nutrient limited environments

NASA Astrophysics Data System (ADS)

Druhan, J. L.; Giannetta, M.; Sanford, R. A.

2017-12-01

In recent years, reactive transport principles have expanded from early applications, largely based in contaminant hydrology, to a wide range of biologically mediated redox environments including marine sedimentary diagenesis, terrestrial metal ore deposits, soils, and critical zone weathering profiles. A common observation across this diversity of systems is that they often function under energetically limited conditions in comparison to those typical of contaminated aquifers subject to engineered remediation techniques. As a result, the kinetic rate expressions traditionally employed within reactive transport frameworks to simulate microbially mediated redox transformations have required modification. This was recognized in a series of seminal papers by Jin and Bethke (2005, 2007) in which the authors expanded upon a Monod rate law to include a thermodynamic potential factor `Ft' which exerts a limitation on the overall rate based on the thermodynamic driving force of the electron transfer reaction. This new rate expression is now commonly implemented within many of the major reactive transport software packages, though appropriate application has yet to be thoroughly demonstrated. Notably, the characteristically large partitioning of stable isotopes during microbially mediated reactions, which is extensively utilized to identify and quantify these redox transformations, has yet to be simulated under conditions in which the Ft term may be expected to exert a significant mass dependent influence. Here, we develop a series of simplified simulations for the microbially mediated reduction of sulfate based on the datasets reported by Jin and Bethke, and apply appropriate mass-bias within the Ft term to consider the extent to which the resulting isotopic fractionation is consistent with that observed in energetically limited systems. We show that the Ft term can exert a significant influence on the observed fractionation factor under common environmental conditions

Wet and cold climate conditions recorded by coral geochemical proxies during the beginning of the first millennium CE in the northern South China Sea

NASA Astrophysics Data System (ADS)

Xiao, Hangfang; Deng, Wenfeng; Chen, Xuefei; Wei, Gangjian; Zeng, Ti; Zhao, Jian-xin

2017-03-01

The past two millennia include some distinct climate intervals, such as the Medieval Warm Period (MWP) and the Little Ice Age (LIA), which were caused by natural forcing factors, as well as the Current Warm Period (CWP) that has been linked to anthropogenic factors. Therefore, this period has been of great interest to climate change researchers. However, most studies are based on terrestrial proxy records, historical documentary data, and simulation results, and the ocean and the tropical record are very limited. The Eastern Han, Three Kingdoms, and Western Jin periods (25-316 CE) cover the beginning first millennium CE in China, and were characterized by a cold climate and frequent wars and regime changes. This study used paired Sr/Ca and δ18O series recovered from a fossil coral to reconstruct the sea surface water conditions during the late Eastern Han to Western Jin periods (167-309 CE) at Wenchang, eastern Hainan Island in the northern South China Sea (SCS), to investigate climate change at this time. The long-term sea surface temperature (SST) during the study interval was 25.1 °C, which is about 1.5 °C lower than that of the CWP (26.6 °C). Compared with the average value of 0.40‰ during the CWP, the long-term average seawater δ18O (-0.06‰) was more negative. These results indicate that the climate conditions during the study period were cold and wet and comparable with those of the LIA. This colder climate may have been associated with the weaker summer solar irradiance. The wet conditions were caused by the reduced northward shift of the intertropical convergence zone/monsoon rainbelt associated with the retreat of the East Asian summer monsoon. Interannual and interdecadal climate variability may also have contributed to the variations in SST and seawater δ18O recorded over the study period.

Phylogeny and classification of the East Asian Amitostigma alliance (Orchidaceae: Orchideae) based on six DNA markers.

PubMed

Tang, Ying; Yukawa, Tomohisa; Bateman, Richard M; Jiang, Hong; Peng, Hua

2015-05-26

Tribe Orchideae dominates the orchid flora of the temperate Northern Hemisphere but its representatives in East Asia had been subject to less intensive phylogenetic study than those in Eurasia and North America. Although this situation was improved recently by the molecular phylogenetic study of Jin et al., comparatively few species were analyzed from the species-rich and taxonomically controversial East Asian Amitostigma alliance. Here, we present a framework nrITS tree of 235 accessions of Orchideae plus an in-depth analysis of 110 representative accessions, encompassing most widely recognized species within the alliance, to elucidate their relationships. We used parsimony, likelihood and Bayesian approaches to generate trees from data for two nuclear (nrITS, low-copy Xdh) and four chloroplast (matK, psbA-trnH, trnL-F, trnS-trnG) markers. Nuclear and plastid data were analyzed separately due to a few hard incongruences that most likely reflect chloroplast capture. Our results suggest key phylogenetic placements for Sirindhornia and Brachycorythis, and confirm previous assertions that the Amitostigma alliance is monophyletic and sister to the Eurasian plus European clades of subtribe Orchidinae. Seven robust clades are evident within the alliance, but none corresponds precisely with any of the traditional genera; the smaller and more morphologically distinct genera Tsaiorchis, Hemipilia, Neottianthe and Hemipiliopsis are monophyletic but each is nested within a polyphyletic plexus of species attributed to either Ponerorchis or the most plesiomorphic genus, Amitostigma. Two early-divergent clades that escaped analysis by Jin et al. undermine their attempt to circumscribe an expanded monophyletic genus Ponerorchis. We provide a new framework on the complex phylogenetic relationships between Amitostigma and other genera traditionally included in its alliance; based on which, we combine the entire Amitostigma alliance into a morphologically and molecularly

Fine mapping of a dominantly inherited powdery mildew resistance major-effect QTL, Pm1.1, in cucumber identifies a 41.1 kb region containing two tandemly arrayed cysteine-rich receptor-like protein kinase genes.

PubMed

Xu, Xuewen; Yu, Ting; Xu, Ruixue; Shi, Yang; Lin, Xiaojian; Xu, Qiang; Qi, Xiaohua; Weng, Yiqun; Chen, Xuehao

2016-03-01

A dominantly inherited major-effect QTL for powdery mildew resistance in cucumber was fine mapped. Two tandemly arrayed cysteine-rich receptor-like protein kinase genes were identified as the most possible candidates. Powdery mildew (PM) is one of the most severe fungal diseases of cucumber (Cucumis sativus L.) and other cucurbit crops, but the molecular genetic mechanisms of powdery mildew resistance in cucurbits are still poorly understood. In this study, through marker-assisted backcrossing with an elite cucumber inbred line, D8 (PM susceptible), we developed a single-segment substitution line, SSSL0.7, carrying 95 kb fragment from PM resistance donor, Jin5-508, that was defined by two microsatellite markers, SSR16472 and SSR16881. A segregating population with 3600 F2 plants was developed from the SSSL0.7 × D8 mating; segregation analysis confirmed a dominantly inherited major-effect QTL, Pm1.1 in cucumber chromosome 1 underlying PM resistance in SSSL0.7. New molecular markers were developed through exploring the next generation resequenced genomes of Jin5-508 and D8. Linkage analysis and QTL mapping in a subset of the F2 plants delimited the Pm1.1 locus into a 41.1 kb region, in which eight genes were predicted. Comparative gene expression analysis revealed that two concatenated genes, Csa1M064780 and Csa1M064790 encoding the same function of a cysteine-rich receptor-like protein kinase, were the most likely candidate genes. GFP fusion protein-aided subcellular localization indicated that both candidate genes were located in the plasma membrane, but Csa1M064780 was also found in the nucleus. This is the first report of dominantly inherited PM resistance in cucumber. Results of this study will provide new insights into understanding the phenotypic and genetic mechanisms of PM resistance in cucumber. This work should also facilitate marker-assisted selection in cucumber breeding for PM resistance.

Position-specific isotope modeling of organic micropollutants transformations through different reaction pathways

NASA Astrophysics Data System (ADS)

Jin, Biao; Rolle, Massimo

2016-04-01

Organic compounds are produced in vast quantities for industrial and agricultural use, as well as for human and animal healthcare [1]. These chemicals and their metabolites are frequently detected at trace levels in fresh water environments where they undergo degradation via different reaction pathways. Compound specific stable isotope analysis (CSIA) is a valuable tool to identify such degradation pathways in different environmental systems. Recent advances in analytical techniques have promoted the fast development and implementation of multi-element CSIA. However, quantitative frameworks to evaluate multi-element stable isotope data and incorporating mechanistic information on the degradation processes [2,3] are still lacking. In this study we propose a mechanism-based modeling approach to simultaneously evaluate concentration as well as bulk and position-specific multi-element isotope evolution during the transformation of organic micropollutants. The model explicitly simulates position-specific isotopologues for those atoms that experience isotope effects and, thereby, provides a mechanistic description of isotope fractionation occurring at different molecular positions. We validate the proposed approach with the concentration and multi-element isotope data of three selected organic micropollutants: dichlorobenzamide (BAM), isoproturon (IPU) and diclofenac (DCF). The model precisely captures the dual element isotope trends characteristic of different reaction pathways and their range of variation consistent with observed multi-element (C, N) bulk isotope fractionation. The proposed approach can also be used as a tool to explore transformation pathways in scenarios for which position-specific isotope data are not yet available. [1] Schwarzenbach, R.P., Egli, T., Hofstetter, T.B., von Gunten, U., Wehrli, B., 2010. Global Water Pollution and Human Health. Annu. Rev. Environ. Resour. doi:10.1146/annurev-environ-100809-125342. [2] Jin, B., Haderlein, S.B., Rolle, M

Image Feature Detection and Matching in Underwater Conditions

DTIC Science & Technology

2010-04-01

and ||jlr< li "-Hjj3 < l l=1’-’N „ (17) 0 if k 7^ argmin||r’ — s||2 or k = argmin||r’ - s||2 and Jin.) ’K. > t i=l N i=l N l|r Ŗ matchRNN(fl...Affix (v*01)[F-0_3 O He-un Affine (V Mil 1 F -0M •’ li •« \\irii« a,, lit i I 0-25 (a) SIFT with Nearest Neighbor Matching (b) GLOH...F - 0 𔄁 • Htm* I «pl.ee It. 3 0) | F - 0 17 -*-Hini»-L«(itaM (({,- 10)|F-0.I - He- Mian [ «place <V (I II I 0 < & He-un-Laplace (Z- 3 0

Fast and accurate estimation of the covariance between pairwise maximum likelihood distances.

PubMed

Gil, Manuel

2014-01-01

Pairwise evolutionary distances are a model-based summary statistic for a set of molecular sequences. They represent the leaf-to-leaf path lengths of the underlying phylogenetic tree. Estimates of pairwise distances with overlapping paths covary because of shared mutation events. It is desirable to take these covariance structure into account to increase precision in any process that compares or combines distances. This paper introduces a fast estimator for the covariance of two pairwise maximum likelihood distances, estimated under general Markov models. The estimator is based on a conjecture (going back to Nei & Jin, 1989) which links the covariance to path lengths. It is proven here under a simple symmetric substitution model. A simulation shows that the estimator outperforms previously published ones in terms of the mean squared error.

Fast and accurate estimation of the covariance between pairwise maximum likelihood distances

PubMed Central

2014-01-01

Pairwise evolutionary distances are a model-based summary statistic for a set of molecular sequences. They represent the leaf-to-leaf path lengths of the underlying phylogenetic tree. Estimates of pairwise distances with overlapping paths covary because of shared mutation events. It is desirable to take these covariance structure into account to increase precision in any process that compares or combines distances. This paper introduces a fast estimator for the covariance of two pairwise maximum likelihood distances, estimated under general Markov models. The estimator is based on a conjecture (going back to Nei & Jin, 1989) which links the covariance to path lengths. It is proven here under a simple symmetric substitution model. A simulation shows that the estimator outperforms previously published ones in terms of the mean squared error. PMID:25279263

[Inheritance on and innovation of traditional Chinese medicine (TCM) flavor theory and TCM flavor standardization principle flavor theory in Compendium of Materia Medica].

PubMed

Zhang, Wei; Zhang, Rui-xian; Li, Jian

2015-12-01

All previous literatures about Chinese herbal medicines show distinctive traditional Chinese medicine (TCM) flavors. Compendium of Materia Medica is an influential book in TCM history. The TCM flavor theory and flavor standardization principle in this book has important significance for modern TCM flavor standardization. Compendium of Materia Medica pays attention to the flavor theory, explain the relations between the flavor of medicine and its therapeutic effects by means of Neo-Confucianism of the Song and Ming Dynasties. However,the book has not reflected and further developed the systemic theory, which originated in the Jin and Yuan dynasty. In Compendium of Materia Medica , flavor are standardized just by tasting medicines, instead of deducing flavors. Therefore, medicine tasting should be adopted as the major method to standardize the flavor of medicine.

Panic-attack-induced transient leukocytosis in a healthy male: a case report.

PubMed

Iskandar, Joseph W; Griffeth, Benjamin; Sapra, Mamta; Singh, Karamjit; Giugale, Juan M

2011-01-01

The lifetime prevalence of panic attacks is 28.3% in American adults 18 years and older. The age of onset of panic attack extends throughout adulthood; however, it typically develops in early adulthood, with median age of onset of 22 years [Kessler R.C., Chiu W.T., Jin R., Ruscio A.M., Shear K., Walters E.E. The epidemiology of panic attacks, panic disorder, and agoraphobia in the National Comorbidity Survey Replication. Arch Gen Psychiatry. 2006 Apr;63(4):415-24.]. As reported in our case, panic attacks could induce transient leukocytosis in healthy adults. If practitioners recognize this association, expensive investigations and extensive hospital stays may be prevented, although prudent practice would likely still require some type of investigations. Copyright © 2011 Elsevier Inc. All rights reserved.

Parachironomus lenz from china and Japan (Diptera, chironomidae).

PubMed

Yan, Chun-Cai; Yan, Jiao; Jiang, Li; Guo, Qin; Liu, Ting; Ge, Xin-Yu; Wang, Xin-Hua; Pan, Bao-Ping

2015-01-01

Members of the genus Parachironomus Lenz known from China and Japan are revised, and a key to their male adults is given. Parachironomuspoyangensis sp. n. is described in this life stage. Parachironomusfrequens (Johannsen) and Parachironomusmonochromus (van der Wulp) are recorded from China for the first time, thus are redescribed from Chinese specimens. Parachironomuskamaabeus Sasa & Tanaka and Parachironomustoneabeus Sasa & Tanaka are new junior synonyms of Parachironomusfrequens. Three Chinese or Japanese species formerly placed in Parachironomus are transferred to other genera, resulting in the new combinations Cryptochironomusinafegeus (Sasa, Kitami & Suzuki), Demicryptochironomus (Irmakia) lobus (Yan, Sæther, Jin & Wang), and Microchironomuslacteipennis (Kieffer). Chironomussauteri Kieffer, Parachironomuskisobilobalis Sasa & Kondo and Parachironomuskuramaexpandus Sasa are removed from Parachironomus; the last of these three denotes a valid species of uncertain generic placement, the first two are nomina dubia.

Thermodynamic Database for the NdO(1.5)-YO(1.5)-YbO(1.5)-ScO(1.5)-ZrO2 System

NASA Technical Reports Server (NTRS)

Jacobson, Nathan S.; Copland, Evan H.; Kaufman, Larry

2001-01-01

A database for YO(1.5)-NdO(1.5)-YbO(1.5)-ScO(1.5)-ZrO2 for ThermoCalc (ThermoCalc AB, Stockholm, Sweden) has been developed. The basis of this work is the YO(1.5)-ZrO2 assessment by Y. Du, Z. Jin, and P. Huang, 'Thermodynamic Assessment of the ZrO2-YO(1.5) System'. Experimentally only the YO(1.5)-ZrO2 system has been well-studied. All other systems are only approximately known. The major simplification in this work is the treatment of each single cation unit as a component. The pure liquid oxides are taken as reference states and two term lattice stability descriptions are used for each of the components. The limited experimental phase diagrams are reproduced.

Identification and characterization of pesticide metabolites in Brassica species by liquid chromatography travelling wave ion mobility quadrupole time-of-flight mass spectrometry (UPLC-TWIMS-QTOF-MS).

PubMed

Bauer, Anna; Luetjohann, Jens; Hanschen, Franziska S; Schreiner, Monika; Kuballa, Jürgen; Jantzen, Eckard; Rohn, Sascha

2018-04-01

A new mass spectrometric method for evaluating metabolite formation of the pesticides thiacloprid, azoxystrobin, and difenoconazole was developed for the Brassica species pak choi and broccoli. Both, distribution and transformation kinetics of the active compounds and their metabolites were analyzed by UPLC-TWIMS-QTOF-MS. Additionally, HR-MS analysis and structure elucidation tools such as diagnostic ions, isotopic matches, and collision cross sections were applied for metabolites identification. Following the application of two plant protection products (containing the above-mentioned active compounds) in a greenhouse study plant material was cryo-milled and extracted with water/methanol. The residual levels of active compounds were identified at certain timepoints during pre-harvest intervals and in the final products. Different phase I and phase II metabolites of the pesticides were identified in different plant organs such as leaves, stems, (broccoli) heads, and roots. Three individual degradation pathways and distribution profiles are suggested including eight thiacloprid, eleven azoxystrobin and three difenoconazole metabolites. Copyright © 2017. Published by Elsevier Ltd.

Time-Frequency Characterization of Cerebral Hemodynamics of Migraine Sufferers as Assessed by NIRS Signals

NASA Astrophysics Data System (ADS)

Molinari, Filippo; Rosati, Samanta; Liboni, William; Negri, Emanuela; Mana, Ornella; Allais, Gianni; Benedetto, Chiara

2010-12-01

Near-infrared spectroscopy (NIRS) is a noninvasive system for the real-time monitoring of the concentration of oxygenated ([InlineEquation not available: see fulltext.]) and reduced (HHb) hemoglobin in the brain cortex. [InlineEquation not available: see fulltext.] and HHb concentrations vary in response to cerebral autoregulation. Sixty-eight women (14 migraineurs without aura, 49 migraineurs with aura, and 5 controls) performed breath-holding and hyperventilation during NIRS recordings. Signals were processed using the Choi-Williams time-frequency transform in order to measure the power variation of the very-low frequencies (VLF: 20-40 mHz) and of the low frequencies (LF: 40-140 mHz). Results showed that migraineurs without aura present different LF and VLF power levels than controls and migraineurs with aura. The accurate power measurement of the time-frequency analysis allowed for the discrimination of the subjects' hemodynamic patterns. The time-frequency analysis of NIRS signals can be used in clinical practice to assess cerebral hemodynamics.

Effect of supplemental UV-A irradiation in solid-state lighting on the growth and phytochemical content of microgreens

NASA Astrophysics Data System (ADS)

Brazaitytė, A.; Viršilė, A.; Jankauskienė, J.; Sakalauskienė, S.; Samuolienė, G.; Sirtautas, R.; Novičkovas, A.; Dabašinskas, L.; Miliauskienė, J.; Vaštakaitė, V.; Bagdonavičienė, A.; Duchovskis, P.

2015-01-01

In this study, we sought to find and employ positive effects of UV-A irradiation on cultivation and quality of microgreens. Therefore, the goal of our study was to investigate the influence of 366, 390, and 402 nm UV-A LED wavelengths, supplemental for the basal solid-state lighting system at two UV-A irradiation levels on the growth and phytochemical contents of different microgreen plants. Depending on the species, supplemental UV-A irradiation can improve antioxidant properties of microgreens. In many cases, a significant increase in the investigated phytochemicals was found under 366 and 390 nm UV-A wavelengths at the photon flux density (12.4 μmol m-2 s-1). The most pronounced effect of supplemental UV-A irradiation was detected in pak choi microgreens. Almost all supplemental UV-A irradiation treatments resulted in increased leaf area and fresh weight, in higher 2,2-diphenyl-1-picrylhydrazyl free-radical scavenging activity, total phenols, anthocyanins, ascorbic acid, and α-tocopherol.

Effect of Solid Biological Waste Compost on the Metabolite Profile of Brassica rapa ssp. chinensis

PubMed Central

Neugart, Susanne; Wiesner-Reinhold, Melanie; Frede, Katja; Jander, Elisabeth; Homann, Thomas; Rawel, Harshadrai M.; Schreiner, Monika; Baldermann, Susanne

2018-01-01

Large quantities of biological waste are generated at various steps within the food production chain and a great utilization potential for this solid biological waste exists apart from the current main usage for the feedstuff sector. It remains unclear how the usage of biological waste as compost modulates plant metabolites. We investigated the effect of biological waste of the processing of coffee, aronia, and hop added to soil on the plant metabolite profile by means of liquid chromatography in pak choi sprouts. Here we demonstrate that the solid biological waste composts induced specific changes in the metabolite profiles and the changes are depending on the type of the organic residues and its concentration in soil. The targeted analysis of selected plant metabolites, associated with health beneficial properties of the Brassicaceae family, revealed increased concentrations of carotenoids (up to 3.2-fold) and decreased amounts of glucosinolates (up to 4.7-fold) as well as phenolic compounds (up to 1.5-fold). PMID:29616051

A Theoretical Investigation of the Effects of Cs and O2 Adsorbates on Field Emission Properties of Single Wall Carbon Nanotubes

NASA Astrophysics Data System (ADS)

Akdim, Brahim; Duan, Xiaofeng; Pachter, Ruth

2003-03-01

We present a comprehensive theoretical study on the effects of Cs and O2 adsorbates on the field emission properties of single-wall carbon nanotubes (SWCNTs). Experimentally, O2 adsorption was shown to cause current suppression [1], while a current enhancement has been reported for Cs deposition on CNTs [2]. In this work, we investigated the adsorption mechanisms of Cs and O2 at the tips of capped and uncapped C(5,5) CNTs, using density functional theory, in order to gain insight into the effects on emission characteristics. Structural and electronic properties will be discussed in detail. We also report on the effects of an applied field on the reaction mechanisms. [1] S. C. Lim, Y. C. Choi, H. J. Jeong, Y. M. Shin, K. H. An, D. J. Bae, Y. H. Lee, N. S. Lee, and J. M. Kim, Adv. Mater. 13, 1563 (2001). [2] A. Wadhawan, R. E. Stallcup II, and J. M. Perez, Apply. Phys. Lett. 78, 108 (2001).

An experimental assessment of resistance reduction and wake modification of a kvlcc model by using outer-layer vertical blades

NASA Astrophysics Data System (ADS)

An, Nam Hyun; Ryu, Sang Hoon; Chun, Ho Hwan; Lee, Inwon

2014-03-01

In this study, an experimental investigation has been made of the applicability of outer-layer vertical blades to real ship model. After first devised by Hutchins and Choi (2003), the outer-layer vertical blades demonstrated its effectiveness in reducing total drag of flat plate (Park et al., 2011) with maximum drag reduction of 9.6%. With a view to assessing the effect in the flow around a ship, the arrays of outer-layer vertical blades have been installed onto the side bottom and flat bottom of a 300k KVLCC model. A series of towing tank test has been carried out to investigate resistance (CTM) reduction efficiency and improvement of stern wake distribution with varying geometric parameters of the blades array. The installation of vertical blades led to the CTM reduction of 2.15~2.76% near the service speed. The nominal wake fraction was affected marginally by the blades array and the axial velocity distribution tended to be more uniform by the blades array.

Channel Simulation in Quantum Metrology

NASA Astrophysics Data System (ADS)

Laurenza, Riccardo; Lupo, Cosmo; Spedalieri, Gaetana; Braunstein, Samuel L.; Pirandola, Stefano

2018-04-01

In this review we discuss how channel simulation can be used to simplify the most general protocols of quantum parameter estimation, where unlimited entanglement and adaptive joint operations may be employed. Whenever the unknown parameter encoded in a quantum channel is completely transferred in an environmental program state simulating the channel, the optimal adaptive estimation cannot beat the standard quantum limit. In this setting, we elucidate the crucial role of quantum teleportation as a primitive operation which allows one to completely reduce adaptive protocols over suitable teleportation-covariant channels and derive matching upper and lower bounds for parameter estimation. For these channels,wemay express the quantum Cramér Rao bound directly in terms of their Choi matrices. Our review considers both discrete- and continuous-variable systems, also presenting some new results for bosonic Gaussian channels using an alternative sub-optimal simulation. It is an open problem to design simulations for quantum channels that achieve the Heisenberg limit.

Target Identification Using Harmonic Wavelet Based ISAR Imaging

NASA Astrophysics Data System (ADS)

Shreyamsha Kumar, B. K.; Prabhakar, B.; Suryanarayana, K.; Thilagavathi, V.; Rajagopal, R.

2006-12-01

A new approach has been proposed to reduce the computations involved in the ISAR imaging, which uses harmonic wavelet-(HW) based time-frequency representation (TFR). Since the HW-based TFR falls into a category of nonparametric time-frequency (T-F) analysis tool, it is computationally efficient compared to parametric T-F analysis tools such as adaptive joint time-frequency transform (AJTFT), adaptive wavelet transform (AWT), and evolutionary AWT (EAWT). Further, the performance of the proposed method of ISAR imaging is compared with the ISAR imaging by other nonparametric T-F analysis tools such as short-time Fourier transform (STFT) and Choi-Williams distribution (CWD). In the ISAR imaging, the use of HW-based TFR provides similar/better results with significant (92%) computational advantage compared to that obtained by CWD. The ISAR images thus obtained are identified using a neural network-based classification scheme with feature set invariant to translation, rotation, and scaling.

The effects of divided attention at study and test on false recognition: a comparison of DRM and categorized lists.

PubMed

Knott, Lauren M; Dewhurst, Stephen A

2007-12-01

Three experiments investigated the effects of divided attention at encoding and retrieval on false recognition. In Experiment 1, participants studied word lists in either full or divided attention (random number generation) conditions and then took part in a recognition test with full attention. In Experiment 2, after studying word lists with full attention, participants carried out a recognition test with either full or divided attention. Experiment 3 manipulated attention at both study and test. We also compared Deese/Roediger-McDermott (DRM) and categorized lists, due to recent claims regarding the locus of false memories produced by such lists (Smith, Gerkens, Pierce, & Choi, 2002). With both list types, false "remember" responses were reduced by divided attention at encoding and increased by divided attention at retrieval. The findings suggest that the production of false memories occurs as a result of the generation of associates at encoding and failures of source monitoring retrieval. Crucially, this is true for both DRM and categorized lists.

Quantum resource theory of non-stabilizer states in the one-shot regime

NASA Astrophysics Data System (ADS)

Ahmadi, Mehdi; Dang, Hoan; Gour, Gilad; Sanders, Barry

Universal quantum computing is known to be impossible using only stabilizer states and stabilizer operations. However, addition of non-stabilizer states (also known as magic states) to quantum circuits enables us to achieve universality. The resource theory of non-stablizer states aims at quantifying the usefulness of non-stabilizer states. Here, we focus on a fundamental question in this resource theory in the so called single-shot regime: Given two resource states, is there a free quantum channel that will (approximately or exactly) convert one to the other?. To provide an answer, we phrase the question as a semidefinite program with constraints on the Choi matrix of the corresponding channel. Then, we use the semidefinite version of the Farkas lemma to derive the necessary and sufficient conditions for the conversion between two arbitrary resource states via a free quantum channel. BCS appreciates financial support from Alberta Innovates, NSERC, China's 1000 Talent Plan and the Institute for Quantum Information and Matter.

A Multi-Mode Blade Damping Control using Shunted Piezoelectric Transducers with Active Feedback Structure

NASA Technical Reports Server (NTRS)

Choi, Benjamin; Morrison, Carlos; Min, James

2009-01-01

The Structural Dynamics and. Mechanics branch (RXS) is developing smart adaptive structures to improve fan blade damping at resonances using piezoelectric (PE) transducers. In this presentation, only one shunted PE transducer was used to demonstrate active control of multi-mode blade resonance damping on a titanium alloy (Ti-6A1-4V) flat plate model, regardless of bending, torsion, and 2-stripe modes. This work would have a significant impact on the conventional passive shunt damping world because the standard feedback control design tools can now be used to design and implement electric shunt for vibration control. In other words, the passive shunt circuit components using massive inductors and. resistors for multi-mode resonance control can be replaced with digital codes. Furthermore, this active approach with multi patches can simultaneously control several modes in the engine operating range. Dr. Benjamin Choi presented the analytical and experimental results from this work at the Propulsion-Safety and. Affordable Readiness (P-SAR) Conference in March, 2009.

Evaluation of treatment response and resistance in metastatic renal cell cancer (mRCC) using integrated 18F-Fluorodeoxyglucose (18F-FDG) positron emission tomography/magnetic resonance imaging (PET/MRI); The REMAP study.

PubMed

Kelly-Morland, Christian; Rudman, Sarah; Nathan, Paul; Mallett, Susan; Montana, Giovanni; Cook, Gary; Goh, Vicky

2017-06-02

Tyrosine kinase inhibitors are the first line standard of care for treatment of metastatic renal cell carcinoma (RCC). Accurate response assessment in the setting of antiangiogenic therapies remains suboptimal as standard size-related response criteria do not necessarily accurately reflect clinical benefit, as they may be less pronounced or occur later in therapy than devascularisation. The challenge for imaging is providing timely assessment of disease status allowing therapies to be tailored to ensure ongoing clinical benefit. We propose that combined assessment of morphological, physiological and metabolic imaging parameters using 18F-fluorodeoxyglucose positron emission tomography/magnetic resonance imaging ( 18 F-FDG PET/MRI) will better reflect disease behaviour, improving assessment of response/non-response/relapse. The REMAP study is a single-centre prospective observational study. Eligible patients with metastatic renal cell carcinoma, planned for systemic therapy, with at least 2 lesions will undergo an integrated 18 F-FDG PET and MRI whole body imaging with diffusion weighted and contrast-enhanced multiphasic as well as standard anatomical MRI sequences at baseline, 12 weeks and 24 weeks of systemic therapy allowing 18 F-FDG standardised uptake value (SUV), apparent diffusion co-efficient (ADC) and normalised signal intensity (SI) parameters to be obtained. Standard of care contrast-enhanced computed tomography CT scans will be performed at equivalent time-points. CT response categorisation will be performed using RECIST 1.1 and alternative (modified)Choi and MASS criteria. The reference standard for disease status will be by consensus panel taking into account clinical, biochemical and conventional imaging parameters. Intra- and inter-tumoural heterogeneity in vascular, diffusion and metabolic response/non-response will be assessed by image texture analysis. Imaging will also inform the development of computational methods for automated disease status

[Research on southward spreading of Hejian' Theory in the Yuan Dynasty].

PubMed

Li, Y Q

2017-03-28

Hejian' Theory was flourished in the Dading reign of the Jin Dynasty, while the doctors of the Southern Song Dynasty didn't know Hejian's Theory. As Southern Song was overthrown by the Yuan Dynasty, Hejian' Theory began to spread to the South. Hejian's descendants, disciples and those doctors studied this Theory personally all contributed to the Theory's spreading to the South in the Yuan Dynasty. In the meantime, Liu Hejian's descendants moved to Jiangxi province later as well as those studying the Theory personally also made similar contributions. His disciples, especially Jinshan Futu transmitted the Theory to Luo Zhiti, then to Zhu Danxi, all contributed to the southward diffusion too. The local medical officer who inherited the Theory expanded its influencing area. The inheritors' medical theory was not just limited to Hejian's Theory only, reflecting the academic progress at that time.

Archaeobotanical Study of Ancient Food and Cereal Remains at the Astana Cemeteries, Xinjiang, China

PubMed Central

Chen, Tao; Wu, Yan; Zhang, Yongbing; Wang, Bo; Hu, Yaowu; Wang, Changsui; Jiang, Hongen

2012-01-01

Starch grain, phytolith and cereal bran fragments were analyzed in order to identify the food remains including cakes, dumplings, as well as porridge unearthed at the Astana Cemeteries in Turpan of Xinjiang, China. The results suggest that the cakes were made from Triticum aestivum while the dumplings were made from Triticum aestivum, along with Setaria italica. The ingredients of the porridge remains emanated from Panicum miliaceum. Moreover, direct macrobotantical evidence of the utilization of six cereal crops, such as Triticum aestivum, Hordeum vulgare var. coeleste, Panicum miliaceum, Setaria italica, Cannabis sativa, and Oryza sativa in the Turpan region during the Jin and Tang dynasties (about 3rd to 9th centuries) is also presented. All of these cereal crops not only provided food for the survival of the indigenous people, but also spiced up their daily life. PMID:23028807

Rocky Mountain Arsenal North Boundary Treatment Facility: Chemical Data, 1985. Volume 2

DTIC Science & Technology

1986-04-01

SEP OCT NOV DEC 86 SAMPLE DATE (YEAR AND MONTH) SITE PNDW35 FOR ISODR 0.7i 0.8 0.7 0.6-1 2 • 0.5 -~ 0,2 0.2 06 II AI DAT IyA. AND ! I SJ F .MAR APR MAY...MONTH) SITE PNDW43 FOR CPMSO so- 40 . 38 30 0 25 ai a a U I I I I I I I U 5 JAN FM MAR APR MAY JiN JL AUG SEP OCT NOV DEC WB SAMPLE DATE ClEAR AND MONTH...I I I I 5 JAN FEB MAR APR MAY JUN JUL AUG SEP OCT NOV DEC S SAMPLE DATE tfEAR AND MONTN) SITE PNDW54 FOR DLDRN 0.7a.6 0.4 0.3 0.2 " AI 0 0 0 I I I I I

[Try to discuss manipulation of the "Feijing Zouqi" needling technique].

PubMed

Zhou, Dan; Gao, Ying; Wang, Fu-chun

2008-03-01

Based on description of "Feijing Zouqi" needling methods in Jin Zhen Fu (Rhyme Prose of Golden Needle) written by Xu Feng, and explain and analyze the descriptions of "Feijing Zouqi" needling method in Zhenjiu Juying (A Collection of Gems in Acu-Moxibustion) written by Gao Wu, Zhenjiu Wendui written by Wang Ji, Zhenjiu Dacheng (Great Compendium on Acu-Moxibustion) written by Yang Ji-zhou, Yixue Rumen (Elementary Medicine) written by LI Chan and many other works, summarize the technique characteristics of all the "Feijing Zouqi" needling methods. The characteristic of "Qinglong Baiwei" needling method is " first toward the left, then toward the right, slowly move or adjust with the hand"; and "Baihu Yaotou" needling method emphasizes "Tuifang Jinyuan" and "Yaozhen "; key point of "Canggui Tanxue" needling method is "Zuanti Sifang"; Chifeng Yingyuan" needling method emphasizes "Siwei Feixuan".

Geographic List of Prime Contract Awards. Oct 92-Sep 93. FY 93. (Amos, Kentucky-Montgomery County, Maryland). Part 6

DTIC Science & Technology

1994-03-01

r 11 c I0-eJI C1 31 00000P0) 0 (icc C) Cr) M 0 W( D(DE DW D0)o I o0)0 II.’I1)cc jinI 11 ) C\\LC\\m NA NI C111 Mr (’*4 Y MCJMMMMM (nr (YiC ) (ici MCici...0 00 0 0 III0-Ic14򒰌 OW 000 00 00 000 00 00 000> 00 0 00 11 1 l-4N II 1 N N, NN N 4 N NNN > II 10-i- 11 >- z co11111 - I\\ jINI ,-t 0 11 N N 00 Nc 4ɚ...I 0011C U.L 11 c I caoc II 00 11 E I Gao 0r, 1 -- -I .- ---- -- - - - - - - -- ----- 114- I COLD4l II 000000000000000000000000000000000000000000 00 1

[Study on active constituents of traditional Chinese medicine reversing multidrug resistance of tumor cells in vitro].

PubMed

Zhang, H; Yang, L; Liu, S; Ren, L

2001-09-01

To screen drugs reversing multidrug resistance of tumor cells from active constituents of traditional Chinese medicine and to study the reversal action. The kill effects of the drugs on tumor cell lines in vitro were determined with MTT method. The Jin's formula was used to analyse the effect of drug combination. 5 micrograms/ml rhynchophylline, 2 micrograms/ml jatrorrhizine and 1.25 micrograms/ml indirulin could reverse multidrug resistance for vincristine on KBv200 cell line by 16.8, 5.1 and 4 fold respectively. 1.56-12.5 micrograms/ml curcumine combining with vincristine could sensitize antitumor effect both on KB and KBv200 cell lines. All rhynchophylline, jatrorrhizine and indirulin could reverse multidrug resistance for vincristine on KBv200 cell line. Curcumine combinating vincristine could sensitize antitumor effect both on kB and kBv200 cell lines.

Swimming training repercussion on metabolic and structural bone development; benefits of the incorporation of whole body vibration or pilometric training; the RENACIMIENTO project.

PubMed

Gómez-Bruton, A; Gonzalez-Agüero, A; Casajus, J A; Vicente-Rodriguez, German

2014-08-01

Enviromental factors such as exercise participation and nutrition have often been linked to bone improvements. However, not all sports have the same effects, being non-osteogenic sports such as swimming defined as negative or neutral sports to practice regarding bone mass by some authors, similarly exercise-diet interaction in especific groups is still not clear. To present the methodology of the RENACIMENTO project that aims to evaluate body composition and more specifically bone mass by several techniques in adolescent swimmers and to observe the effects and perdurability of whole body vibration (WBV) and jumping intervention (JIN) on body composition and fitness on this population and explore posible diet interactions. Randomized controlled trial. 78 swimmers (12-17 y) and 26 sex- and age-matched controls will participate in this study. Dual energy X-ray, peripheral Quantitative Computed Tomography, Quantitative Ultrasound, Bioelectrical Impedance Analysis, and anthropometry measurements will be performed in order to evaluate body composition. Physical activity, nutrition, pubertal development and socio-economical status may act as confounders of body composition and therefore will also be registered. Several fitness factors regarding strength, endurance, performance and others will also be registered to evaluate differences with controls and act as confounders. A 7-month WBV therapy will be performed by 26 swimmers consisting of a training of 15 minutes 3 times per week. An 8 month JIM will also be performed by 26 swimmers 3 times per week. The remaining 26 swimmers will continue their normal swimming training. Four evaluations will be performed, the first one in order to describe differences between swimmers and controls. The second one to describe the effects of the interventions and the third and fourth evaluations to describe the perdurability of the effects of the WBV and JIN. The RENACIMIENTO project will allow to answer several questions regarding body

Brassica napus Genome Possesses Extraordinary High Number of CAMTA Genes and CAMTA3 Contributes to PAMP Triggered Immunity and Resistance to Sclerotinia sclerotiorum

PubMed Central

Rahman, Hafizur; Xu, You-Ping; Zhang, Xuan-Rui; Cai, Xin-Zhong

2016-01-01

-box-containing genes BAK1 and JIN1, which are essential to the PAMP triggered immunity (PTI) and/or plant resistance to pathogens including S. sclerotiorum. Our results revealed that CAMTA3 negatively regulated PTI probably by directly targeting BAK1 and it also negatively regulated plant defense through suppressing JA signaling pathway probably via directly targeting JIN1. PMID:27200054

Chinese Herbal Medicine for Improving Quality of Life Among Nonsmall Cell Lung Cancer Patients: Overview of Systematic Reviews and Network Meta-Analysis.

PubMed

Wu, Xinyin; Chung, Vincent C H; Lu, Ping; Poon, Simon K; Hui, Edwin P; Lau, Alexander Y L; Balneaves, Lynda G; Wong, Samuel Y S; Wu, Justin C Y

2016-01-01

For patients with nonsmall cell lung cancer (NSCLC) receiving chemotherapy, current clinical evidence has indicated add-on benefit of Chinese herbal medicine (CHM) in improving quality of life (QoL). However, the relative performance among different CHM is unknown. The aim of this overview of systematic reviews (SRs) and network meta-analyses (NMA) is to evaluate the comparative effectiveness of different CHM. Seven electronic databases including both international databases and Chinese databases were searched. SRs focus on randomized controlled trials (RCTs) with comparison of CHM plus chemotherapy against chemotherapy alone on QoL among NSCLC patients were considered eligible. Data from RCTs were extracted for random effect pairwise meta-analyses. Pooled relative risk (RR) with 95% confidence interval (CI) was used to quantify the impact of CHM on QoL. NMA was used to explore the most effective CHM for improving QoL when used with chemotherapy. From 14 SRs, 61 RCTs (n = 4247) assessing 11 different CHM were included. Result from pairwise meta-analyses showed 6 CHM (Kang-lai-te injection, Shei-qi-fu-zheng injection, Compound ku-shen injection, Kang-ai injection, Zi-jin-long tablet, and Shen-fu injection) has significant beneficial effect on QoL among NSCLC patients when used with chemotherapy, even after adjustment for publication bias. Pooled RR varied from 1.38 (95% CI: 1.11-1.72, I2 = 0.0%, Kang-lai-te injection) to 3.36 (95% CI: 1.30-8.66, I2 = 0.0%, Zi-jin-long tablet). One trial comparing Hai-shen-su (a protein extract from Tegillarca granosa L.) plus chemotherapy with chemotherapy also demonstrated beneficial effect of combined treatment (RR = 3.13, 95% CI: 1.41-6.98). Results from NMA showed no differences on the comparative effectiveness among CHM, but Hai-shen-su plus chemotherapy has the highest probability (62.3%) of being the best option for improving QoL. Use of CHM on top of chemotherapy can significantly improve QoL in NSCLC patients. Although Hai

Monitoring the Deformation of High-Rise Buildings in Shanghai Luijiazui Zone by Tomo-Psinsar

NASA Astrophysics Data System (ADS)

Zhou, L. F.; Ma, P. F.; Xia, Y.; Xie, C. H.

2018-05-01

In this study, we utilize a Tomography-based Persistent Scatterers Interferometry (Tomo-PSInSAR) approach for monitoring the deformation performances of high-rise buildings, i.e. SWFC and Jin Mao Tower, in Shanghai Lujiazui Zone. For the purpose of this study, we use 31 Stripmap acquisitions from TerraSAR-X missions, spanning from December 2009 to February 2013. Considering thermal expansion, creep and shrinkage are two long-term movements that occur in high-rise buildings with concrete structures, we use an extended 4-D SAR phase model, and three parameters (height, deformation velocity, and thermal amplitude) are estimated simultaneously. Moreover, we apply a two-tier network strategy to detect single and double PSs with no need for preliminary removal of the atmospheric phase screen (APS) in the study area, avoiding possible error caused by the uncertainty in spatiotemporal filtering. Thermal expansion is illustrated in the thermal amplitude map, and deformation due to creep and shrinkage is revealed in the linear deformation velocity map. The thermal amplitude map demonstrates that the derived thermal amplitude of the two high-rise buildings both dilate and contract periodically, which is highly related to the building height due to the upward accumulative effect of thermal expansion. The linear deformation velocity map reveals that SWFC is subject to deformation during the new built period due to creep and shrinkage, which is height-dependent movements in the linear velocity map. It is worth mention that creep and shrinkage induces movements that increase with the increasing height in the downward direction. In addition, the deformation rates caused by creep and shrinkage are largest at the beginning and gradually decrease, and at last achieve a steady state as time goes infinity. On the contrary, the linear deformation velocity map shows that Jin Mao Tower is almost stable, and the reason is that it is an old built building, which is not influenced by creep

[Historical Study of the Etymological Form and Translational Process of Gout (Tongfeng,)].

PubMed

Cho, Jae-Heung; Jung, Jae Young

2015-08-01

This study aims to address questions regarding the translation of 'gout' into 'tongfeng ()' in East Asia. To this end, the formation process of the origins, 'gout' from Western medicine and 'tongfeng' from Oriental medicine, and the translational process were investigated through the relevant records and literature dating from the 16th century on. Symptoms associated with gout were originally mentioned in ancient Egypt and various terminologies were used to refer to gout, such as podagra, cheiragra and gonogra. The word 'gout', which is derived from Latin, was used for the first time in the 13th century. The reason for this linguistic alteration is thought to be the need for a comprehensive term to cover the various terms for gout in symptomatic body parts, since it can occur concurrently in many joints. However, it took hundreds of years before gout was independently established as a medical term. In oriental medicine, terms describing diseases with features similar to gout include bibing (), lijiefeng (), baihufeng () and tongfeng (). Among them, the concept of 'tongfeng' has been established since the Jin and Yuan dynasties. The cause, prevention and various treatments for tongfeng were proposed throughout the Ming and Qing dynasties. The early translation of gout and tongfeng in East Asia, respectively, is estimated to have occurred in the 18th century. The first literature translating gout in China was 'An English and Chinese Vocabulary in the Court Dialect (yinghua yunfu lijie, )'. From the publication of this book until the late 19th century, gout was translated into an unfamiliar Chinese character 'Jiu feng jiao ()', likely because the translation was done mostly by foreign missionaries at the time, and they created a new word on the basis of Western medicine instead of researching and translating similar diseases in oriental medicine. In Japan, the first book translating gout was 'A Pocket Dictionary of the English and Japanese Language (Eiwa taiyaku

Dark Matter Results from First 98.7 Days of Data from the PandaX-II Experiment.

PubMed

Tan, Andi; Xiao, Mengjiao; Cui, Xiangyi; Chen, Xun; Chen, Yunhua; Fang, Deqing; Fu, Changbo; Giboni, Karl; Giuliani, Franco; Gong, Haowei; Guo, Xuyuan; Han, Ke; Hu, Shouyang; Huang, Xingtao; Ji, Xiangdong; Ju, Yonglin; Lei, Siao; Li, Shaoli; Li, Xiaomei; Li, Xinglong; Liang, Hao; Lin, Qing; Liu, Huaxuan; Liu, Jianglai; Lorenzon, Wolfgang; Ma, Yugang; Mao, Yajun; Ni, Kaixuan; Ren, Xiangxiang; Schubnell, Michael; Shen, Manbin; Shi, Fang; Wang, Hongwei; Wang, Jimin; Wang, Meng; Wang, Qiuhong; Wang, Siguang; Wang, Xuming; Wang, Zhou; Wu, Shiyong; Xiao, Xiang; Xie, Pengwei; Yan, Binbin; Yang, Yong; Yue, Jianfeng; Zeng, Xionghui; Zhang, Hongguang; Zhang, Hua; Zhang, Huanqiao; Zhang, Tao; Zhao, Li; Zhou, Jing; Zhou, Ning; Zhou, Xiaopeng

2016-09-16

We report the weakly interacting massive particle (WIMP) dark matter search results using the first physics-run data of the PandaX-II 500 kg liquid xenon dual-phase time-projection chamber, operating at the China JinPing underground laboratory. No dark matter candidate is identified above background. In combination with the data set during the commissioning run, with a total exposure of 3.3×10^{4}  kg day, the most stringent limit to the spin-independent interaction between the ordinary and WIMP dark matter is set for a range of dark matter mass between 5 and 1000  GeV/c^{2}. The best upper limit on the scattering cross section is found 2.5×10^{-46}  cm^{2} for the WIMP mass 40  GeV/c^{2} at 90% confidence level.

Supernova 2011by in NGC 3972 = Psn J11554556+5519338

NASA Astrophysics Data System (ADS)

Waagen, Elizabeth O.

2011-04-01

Announces discovery of SN 2011by = PSN J11554556+5519338 by Zhangwei Jin (Ningbo, Zhejiang, China) and Xing Gao (Urumqi, Xinjiang, China) on 2011 Apr. 26.8234 UT at magnitude ~14.2 (unfiltered CCD). Spectra obtained on 2011 Apr. 27.5 UT by T. Zhang and Z. Zhou (National Astronomical Observatories of China) and X. Wang (Tsinghua Center for Astrophysics, Tsinghua University) show SN 2011by to be a type-Ia supernova about 10 days before maximum. Initially announced in IAU CBAT Central Bureau Electronic Telegrams 2708 (Daniel W. E. Green, ed.). The object was designated PSN J11554556+5519338 when posted on the Central Bureau's Transient Objects Confirmation Page (TOCP) webpage. Finder charts with sequence may be created using the AAVSO Variable Star Plotter (http://www.aavso.org/vsp). Observations should be submitted to the AAVSO International Database. See full Alert Notice for more details, observations, and links to images.

Gyrokinetic simulation study of magnetic island effects on neoclassical physics and micro-instabilities in a realistic KSTAR plasma

NASA Astrophysics Data System (ADS)

Kwon, Jae-Min; Ku, S.; Choi, M. J.; Chang, C. S.; Hager, R.; Yoon, E. S.; Lee, H. H.; Kim, H. S.

2018-05-01

We perform gyrokinetic simulations to study the effects of a stationary magnetic island on neoclassical flow and micro-instability in a realistic KSTAR plasma condition. Through the simulations, we aim to analyze a recent KSTAR experiment, which was to measure the details of poloidal flow and fluctuation around a stationary (2, 1) magnetic island [M. J. Choi et al., Nucl. Fusion 57, 126058 (2017)]. From the simulations, it is found that the magnetic island can significantly enhance the equilibrium E × B flow. The corresponding flow shearing is strong enough to suppress a substantial portion of ambient micro-instabilities, particularly ∇Te -driven trapped electron modes. This implies that the enhanced E × B flow can sustain a quasi-internal transport barrier for Te in an inner region neighboring the magnetic island. The enhanced E × B flow has a (2, 1) mode structure with a finite phase shift from the mode structure of the magnetic island. It is shown that the flow shear and the fluctuation suppression patterns implied from the simulations are consistent with the observations on the KSTAR experiment.

Brassica vegetables as sources of epithionitriles: Novel secondary products formed during cooking.

PubMed

Hanschen, Franziska S; Kaufmann, Martin; Kupke, Franziska; Hackl, Thomas; Kroh, Lothar W; Rohn, Sascha; Schreiner, Monika

2018-04-15

The epithionitriles, 1-cyano-2,3-epithiopropane, in particular, and 1-cyano-3,4-epithiobutane, are important, but yet underestimated glucosinolate hydrolysis products that are released instead of the cancer preventative isothiocyanates in Brassica vegetables, such as cabbage, broccoli, or pak choi. Here, we characterized the reactivity of 1-cyano-2,3-epithiopropane under aqueous heat treatment conditions and compared our findings to those of the related epithionitriles 1-cyano-3,4-epithiobutane and 1-cyano-4,5-epithiopentane. In contrast to the other epithionitriles, 1-cyano-2,3-epithiopropane is highly reactive. As a result, 2-aminothiophene and dimeric 1,4-dithiane-2,5-diacetonitrile were identified as main products and a reaction mechanism is proposed. Formation of 2-aminothiophene was also observed in cooked white cabbage samples. Moreover, three novel compounds were identified as derivatives of the related epithionitriles. The results imply that apart from isothiocyanates, process-derived compounds should be considered in regards to cancer preventative Brassica vegetable related bioactivity. Copyright © 2017 Elsevier Ltd. All rights reserved.

Time-frequency analysis of SEMG--with special consideration to the interelectrode spacing.

PubMed

Alemu, M; Kumar, Dinesh Kant; Bradley, Alan

2003-12-01

The surface electromyogram (SEMG) is a complex, nonstationary signal. The spectrum of the SEMG is dependent on the force of contraction being generated and other factors like muscle fatigue and interelectrode distance (IED). The spectrum of the signal is time variant. This paper reports the experimental research conducted to study the influence of force of muscle contraction and IED on the SEMG signal using time-frequency (T-F) analysis. Two T-F techniques have been used: Wigner-Ville distribution (WVD) and Choi-Williams distribution (CWD). The experiment was conducted with the help of ten healthy volunteers (five males and five females) who performed isometric elbow flexions of the active right arm at 20%, 50%, and 80% of their maximal voluntary contraction. The SEMG signal was recorded using surface electrodes placed at a distance of 18 and 36 mm over biceps brachii muscle. The results indicate that the two distributions were spread out across the frequency range at smaller IED. Further, regardless of the spacing, both distributions displayed increased spectral compression with time at higher contraction level.

Working channel endoscope in lumbar spine surgery.

PubMed

Choi, G; Lee, S H; Deshpande, K; Choi, H

2014-06-01

Percutaneous endoscopic lumbar discectomy (PELD) is a well established modality in the treatment of patients with herniated lumbar discs. Since the time of its inception towards the end of 20th century, this technique has undergone significant modifications. With better understanding of the patho-anatomy and development of instrumentation the indications for PELD are on the rise. In the modern era of knowledge exchange there have been considerable variations among different endoscopic surgeons about classical indications and the implications of a particular technique pertaining to those indications. During last 15 years of experience in practicing endoscopic surgery, Choi has published many articles, regarding the techniques of PELD, across many scientific journals. In our practice there has been considerable shift from central debulking to discectomy to selective fragmentectomy. With further advancements the span of this technique is definitely on the rise. Here, we wish to share all the published data along with my current practice trends in more precise manner to help newer endoscopic spine surgeons understand the implications and limitations of a working channel endoscope in lumbar spine pathologies.

Genetic similarity analysis within Pyropia yezoensis blades developed from both conchospores and blade archeospores using AFLP(1).

PubMed

He, Linwen; Zhu, Jianyi; Lu, Qinqin; Niu, Jianfeng; Zhang, Baoyu; Lin, Apeng; Wang, Guangce

2013-06-01

Pyropia yezoensis (Ueda) M. S. Hwang et H. G. Choi (previously called Porphyra yezoensis) is an economically important alga. The blades generated from conchospores are genetic chimeras, which are not suitable for genetic similarity analysis. In this study, two types of blades from a single filament of P. yezoensis sporophyte filament were obtained. One type, ConB, consisted of 40 blades that had germinated from conchospores. The other type, ArcB, consisted of 88 blades that had germinated from archeospores released from ConB. Both of them were analyzed by amplified fragment length polymorphism. The low genetic similarity levels for both conchospore-germinated and archeospore-germinated blades demonstrated that the conchcelis we used was cross-fertilized. Furthermore, a higher polymorphic loci ratio (98.6%) was detected in ArcB than in ConB (80.7%), and the average genetic similarity of ArcB (average 0.61) was lower than that of ConB (average 0.71). These differences indicated that genetic analysis using ArcB gives more accurate results. © 2013 Phycological Society of America.

Sustained Local Diversity of Vibrio cholerae O1 Biotypes in a Previously Cholera-Free Country

PubMed Central

2016-01-01

ABSTRACT Although the current cholera pandemic can trace its origin to a specific time and place, many variants of Vibrio cholerae have caused this disease over the last 50 years. The relative clinical importance and geographical distribution of these variants have changed with time, but most remain in circulation. Some countries, such as Mexico and Haiti, had escaped the current pandemic, until large epidemics struck them in 1991 and 2010, respectively. Cholera has been endemic in these countries ever since. A recent retrospective study in mBio presents the results of more than 3 decades of V. cholerae monitoring from environmental and clinical sources in Mexico (S. Y. Choi et al., mBio 7:e02160-15, 2016, http://dx.doi.org/10.1128/mBio.02160-15). It reveals that multiple V. cholerae variants, including classical strains from the previous pandemic, as well as completely novel biotypes, have been circulating in Mexico. This discovery has important implications for the epidemiology and evolution of V. cholerae. PMID:27143391

Sustained Local Diversity of Vibrio cholerae O1 Biotypes in a Previously Cholera-Free Country.

PubMed

Boucher, Yan

2016-05-03

Although the current cholera pandemic can trace its origin to a specific time and place, many variants of Vibrio cholerae have caused this disease over the last 50 years. The relative clinical importance and geographical distribution of these variants have changed with time, but most remain in circulation. Some countries, such as Mexico and Haiti, had escaped the current pandemic, until large epidemics struck them in 1991 and 2010, respectively. Cholera has been endemic in these countries ever since. A recent retrospective study in mBio presents the results of more than 3 decades of V. cholerae monitoring from environmental and clinical sources in Mexico (S. Y. Choi et al., mBio 7:e02160-15, 2016, http://dx.doi.org/10.1128/mBio.02160-15). It reveals that multiple V. cholerae variants, including classical strains from the previous pandemic, as well as completely novel biotypes, have been circulating in Mexico. This discovery has important implications for the epidemiology and evolution of V. cholerae. Copyright © 2016 Boucher.

High-quality draft genome sequence of Gracilimonas tropica CL-CB462 T (DSM 19535 T), isolated from a Synechococcus culture

DOE PAGES

Choi, Dong Han; Ahn, Chisang; Jang, Gwang Il; ...

2015-11-11

Gracilimonas tropica Choi et al. 2009 is a member of order Sphingobacteriales, class Sphingobacteriia. Three species of the genus Gracilimonas have been isolated from marine seawater or a salt mine and showed extremely halotolerant and mesophilic features, although close relatives are extremely halophilic or thermophilic. The type strain of the type species of Gracilimonas, G. tropica DSM19535 T, was isolated from a Synechococcus culture which was established from the tropical sea-surface water of the Pacific Ocean. The genome of the strain DSM19535 T was sequenced through the Genomic Encyclopedia of Type Strains, Phase I: the one thousand microbial genomes project.more » Here, we describe the genomic features of the strain. The 3,831,242 bp long draft genome consists of 48 contigs with 3373 protein-coding and 53 RNA genes. Finally, the strain seems to adapt to phosphate limitation and requires amino acids from external environment. In addition, genomic analyses and pasteurization experiment suggested that G. tropica DSM19535 T did not form spore.« less

Comparison of the effects of measured and computed thermophysical properties of nanofluids on heat transfer performance

DOE Office of Scientific and Technical Information (OSTI.GOV)

Duangthongsuk, Weerapun; Fluid Mechanics, Thermal Engineering and Multiphase Flow Research Laboratory; Wongwises, Somchai

2010-07-15

This article reports a comparison of the differences between using measured and computed thermophysical properties to describe the heat transfer performance of TiO{sub 2}-water nanofluids. In this study, TiO{sub 2} nanoparticles with average diameters of 21 nm and a particle volume fraction of 0.2-1 vol.% are used. The thermal conductivity and viscosity of nanofluids were measured by using transient hot-wire apparatus and a Bohlin rotational rheometer, respectively. The well-known correlations for calculating the thermal conductivity and viscosity of nanofluids were used for describing the Nusselt number of nanofluids and compared with the results from the measured data. The results showmore » that use of the models of thermophysical properties for calculating the Nusselt number of nanofluids gave similar results to use of the measured data. Where there is a lack of measured data on thermophysical properties, the most appropriate models for computing the thermal conductivity and viscosity of the nanofluids are the models of Yu and Choi and Wang et al., respectively. (author)« less

The joint time-frequency spectrogram structure of heptanes boilover noise

NASA Astrophysics Data System (ADS)

Xu, Qiang

2006-04-01

An experiment was conducted to study the noise characteristics in the boilover phenomena. The boilover occurs in the combustion of a liquid fuel floating on water. It will cause a sharp increase in burning rate and external radiation. Explosive burning of the fuel would cause potential safety consequence. Combustion noise accompanies the development of fire and displays different characteristics in typical period. These characteristics can be used to predict the start time of boilover. The acoustic signal in boilover procedure during the combustion of heptanes-water mixture is obtained in a set of experiments. Joint time-frequency analysis (JTFA) method is applied in the treatment of noise data. Several JTFA algorithms were used in the evaluation. These algorithms include Gabor, adaptive spectrogram, cone shape distribution, choi-williams distribution, Wigner-Ville Distribution, and Short Time Fourier Transform with different windows such as rectangular, Blackman, Hamming and Hanning. Time-frequency distribution patterns of the combustion noise are obtained, and they are compared with others from jet flow and small plastic bubble blow up.

The effect of human microtubule-associated-protein tau on the assembly structure of microtubules and its ionic strength dependence

NASA Astrophysics Data System (ADS)

Choi, M. C.; Raviv, U.; Miller, H. P.; Gaylord, M. R.; Kiris, E.; Ventimiglia, D.; Needleman, D. J.; Chung, P. J.; Deek, J.; Lapointe, N.; Kim, M. W.; Wilson, L.; Feinstein, S. C.; Safinya, C. R.

2010-03-01

Microtubules (MTs), 25 nm protein nanotubes, are among the major filamentous elements of the eukaryotic cytoskeleton involved in intracellular trafficking, cell division and the establishment and maintenance of cell shape. Microtubule-associated-protein tau regulates tubulin assembly, MT dynamics and stability. Aberrant tau action has long been correlated with numerous neurodegenerative diseases, including Alzheimer's, and fronto-temporal dementia with Parkinsonism linked to chromosome 17 (FTDP-17) Using synchrotron small angle x-ray scattering (SAXS) and binding assay, we examine the effects of tau on the assembly structure of taxol-stabilized MTs. We find that tau regulates the distribution of protofilament numbers in MTs as reflected in the observed increase in the average radius of MTs with increasing the tau/tubulin molar ratio. Additionally, tau-MT interactions are mediated to a large extent via electrostatic interactions: the binding affinity of tau to MTs is ionic strength dependent. Supported by DOE-BES DE-FG02-06ER46314, NSF DMR-0803103, NIH NS35010, NIH NS13560. (Ref) M.C. Choi, S.C. Feinstein, and C.R. Safinya et al. Biophys. J. 97; 519 (2009).

Well-posedness of the Cauchy problem for models of large amplitude internal waves

NASA Astrophysics Data System (ADS)

Guyenne, Philippe; Lannes, David; Saut, Jean-Claude

2010-02-01

We consider in this paper the 'shallow-water/shallow-water' asymptotic model obtained in Choi and Camassa (1999 J. Fluid Mech. 396 1-36), Craig et al (2005 Commun. Pure. Appl. Math. 58 1587-641) (one-dimensional interface) and Bona et al (2008 J. Math. Pures Appl. 89 538-66) (two-dimensional interface) from the two-layer system with rigid lid, for the description of large amplitude internal waves at the interface of two layers of immiscible fluids of different densities. For one-dimensional interfaces, this system is of hyperbolic type and its local well-posedness does not raise serious difficulties, although other issues (blow-up, loss of hyperbolicity, etc) turn out to be delicate. For two-dimensional interfaces, the system is nonlocal. Nevertheless, we prove that it conserves some properties of 'hyperbolic type' and show that the associated Cauchy problem is locally well posed in suitable Sobolev classes provided some natural restrictions are imposed on the data. These results are illustrated by numerical simulations with emphasis on the formation of shock waves.

Factors influencing post-traumatic stress in Korean forensic science investigators.

PubMed

Yoo, Yang-Sook; Cho, Ok-Hee; Cha, Kyeong-Sook; Boo, Yun-Jeong

2013-09-01

The aim of this study was to understand factors that influence post-traumatic stress (PTS) in Korean forensic science investigators. A total of 111 forensic science investigators were recruited in Korea. PTS was measured using the tool modified by Choi (2001) from the original developed by Foa, Riggs, Dancu, and Rothbaum (1993) based on DSM-IV. Factors influencing PTS included demographic and job-related characteristics, emotional intelligence, and death anxiety. PTS scores were positively correlated with personality type, fatigue from work, and death anxiety. PTS scores were negatively correlated with length of career as a forensic science investigator and emotional intelligence. The factors that had the greatest influence on PTS were death anxiety, years spent as a forensic science investigator, personality type, emotional intelligence, fatigue, and homicide experience. The explanatory power of these six factors was 44.0%. Therefore, it is necessary to regularly evaluate the mental health of those who are vulnerable to PTS. Based on these results, various interventions could be implemented for promoting overall health of the forensic science investigators. Copyright © 2013. Published by Elsevier B.V.

Editorial: Focus on Extra Space Dimensions

NASA Astrophysics Data System (ADS)

Agashe, Kaustubh; Pomarol, Alex

2010-07-01

Experiments at the Large Hadron Collider (LHC) have just started. In addition to verifying the Standard Model (SM) of particle physics, these experiments will probe a new energy frontier and test extensions of the SM. The existence of extra dimensions is one of the most attractive possibilities for physics beyond the SM. This focus issue contains a collection of articles addressing both theoretical and phenomenological aspects of extra-dimensional models. Focus on Extra Space Dimensions Contents Minimal universal extra dimensions in CalcHEP/CompHEP AseshKrishna Datta, Kyoungchul Kong and Konstantin T Matchev Disordered extra dimensions Karim Benakli Codimension-2 brane-bulk matching: examples from six and ten dimensions Allan Bayntun, C P Burgess and Leo van Nierop Gauge threshold corrections in warped geometry Kiwoon Choi, Ian-Woo Kim and Chang Sub Shin Holographic methods and gauge-Higgs unification in flat extra dimensions Marco Serone Soft-wall stabilization Joan A Cabrer, Gero von Gersdorff and Mariano Quirós Warped five-dimensional models: phenomenological status and experimental prospects Hooman Davoudiasl, Shrihari Gopalakrishna, Eduardo Pontón and José Santiago

Comparable Analysis of the Distribution Functions of Runup Heights of the 1896, 1933 and 2011 Japanese Tsunamis in the Sanriku Area

NASA Astrophysics Data System (ADS)

Choi, B. H.; Min, B. I.; Yoshinobu, T.; Kim, K. O.; Pelinovsky, E.

2012-04-01

Data from a field survey of the 2011 tsunami in the Sanriku area of Japan is presented and used to plot the distribution function of runup heights along the coast. It is shown that the distribution function can be approximated using a theoretical log-normal curve [Choi et al, 2002]. The characteristics of the distribution functions derived from the runup-heights data obtained during the 2011 event are compared with data from two previous gigantic tsunamis (1896 and 1933) that occurred in almost the same region. The number of observations during the last tsunami is very large (more than 5,247), which provides an opportunity to revise the conception of the distribution of tsunami wave heights and the relationship between statistical characteristics and number of observations suggested by Kajiura [1983]. The distribution function of the 2011 event demonstrates the sensitivity to the number of observation points (many of them cannot be considered independent measurements) and can be used to determine the characteristic scale of the coast, which corresponds to the statistical independence of observed wave heights.

The Application of Time-Frequency Methods to HUMS

NASA Technical Reports Server (NTRS)

Pryor, Anna H.; Mosher, Marianne; Lewicki, David G.; Norvig, Peter (Technical Monitor)

2001-01-01

This paper reports the study of four time-frequency transforms applied to vibration signals and presents a new metric for comparing them for fault detection. The four methods to be described and compared are the Short Time Frequency Transform (STFT), the Choi-Williams Distribution (WV-CW), the Continuous Wavelet Transform (CWT) and the Discrete Wavelet Transform (DWT). Vibration data of bevel gear tooth fatigue cracks, under a variety of operating load levels, are analyzed using these methods. The new metric for automatic fault detection is developed and can be produced from any systematic numerical representation of the vibration signals. This new metric reveals indications of gear damage with all of the methods on this data set. Analysis with the CWT detects mechanical problems with the test rig not found with the other transforms. The WV-CW and CWT use considerably more resources than the STFT and the DWT. More testing of the new metric is needed to determine its value for automatic fault detection and to develop methods of setting the threshold for the metric.

Prof. Il-Hoi Kim: a tribute.

PubMed

Huys, Rony

2016-10-11

Prof. Il-Hoi Kim was born during the Korean War on 28 February 1952 in Buan, North Jeolla Province (South Korea), near the coast of the Yellow Sea whose tidal flats would become one of his favourite sampling grounds during his scientific career. From an early age he developed an intense interest in natural history in general and marine biology in particular. He obtained his B.Sc. in 1974 at the Department of Biology Education, Gongju National College of Education. Between 1974 and 1976 he was conscripted into the South Korean military during which he progressed to the rank of lieutenant of artillery in the Reserve Officers' Training Corps (ROTC). After his graduation in 1980 at the Department of Zoology, Seoul National University, Il-Hoi Kim moved to the Department of Biology, Gangneung-Wonju National University on the East Sea coast where he was first appointed lecturer (1981) before taking up the position of assistant professor (1983), associate professor (1987) and full professor (1993). In 1985 he had previously completed his Ph.D. dissertation on Korean barnacles at Seoul National University under the supervision of the late Prof. Hoon Soo Kim, a pioneer in marine invertebrate taxonomy and renowned as the father of carcinology in Korea.

Sensitivity of shock boundary-layer interactions to weak geometric perturbations

NASA Astrophysics Data System (ADS)

Kim, Ji Hoon; Eaton, John K.

2016-11-01

Shock-boundary layer interactions can be sensitive to small changes in the inlet flow and boundary conditions. Robust computational models must capture this sensitivity, and validation of such models requires a suitable experimental database with well-defined inlet and boundary conditions. To that end, the purpose of this experiment is to systematically document the effects of small geometric perturbations on a SBLI flow to investigate the flow physics and establish an experimental dataset tailored for CFD validation. The facility used is a Mach 2.1, continuous operation wind tunnel. The SBLI is generated using a compression wedge; the region of interest is the resulting reflected shock SBLI. The geometric perturbations, which are small spanwise rectangular prisms, are introduced ahead of the compression ramp on the opposite wall. PIV is used to study the SBLI for 40 different perturbation geometries. Results show that the dominant effect of the perturbations is a global shift of the SBLI itself. In addition, the bumps introduce weaker shocks of varying strength and angles, depending on the bump height and location. Various scalar validation metrics, including a measure of shock unsteadiness, and their uncertainties are also computed to better facilitate CFD validation. Ji Hoon Kim is supported by an OTR Stanford Graduate Fellowship.

Assessment of the Level of Satisfaction and Unmet Data Needs for Specialty Drug Formulary Decisions in the United States.

PubMed

Choi, Yoonyoung; Navarro, Robert P

2016-04-01

internal economic analyses as having the strongest evidence strength. The study respondents believed that pharmaceutical manufacturers would be best able to satisfy the greatest clinical data unmet need, that is, head-to-head RCTs in specialty drug formulary decisions. This study was not funded by any company or pharmaceutical manufacturer. Navarro has worked as a consultant for Biogen, Purdue Pharma, and Novartis and has offered expert testimony on behalf of AstraZeneca. The authors declare no other potential conflicts of interest. Study design was contributed primarily by Navarro, along with Choi. Choi took the lead in data collection and interpretation, assisted by Navarro. Both authors contributed equally to manuscript writing and revision.

The Hercules Satellite: A Stellar Stream in the Milky Way Halo?

NASA Astrophysics Data System (ADS)

Jin, S.; Martin, N. F.

2011-07-01

We investigate the possibility that Hercules, a recently discovered Milky Way satellite, is a stellar stream in the process of formation. This hypothesis is motivated by Hercules' highly elongated shape as well as the measurement of a tentative radial velocity gradient along its body (Adén et al. 2009a). The application of simple analytical techniques (Jin & Lynden-Bell 2007) on radial velocity data of its member stars provides tight constraints on the tangential velocity of the system (-16-22+6 kms-1, relative to the Galactic Standard of Rest). Combining this with its large receding velocity (145 km s-1) and distance (138 kpc) yields an orbit that would have taken Hercules to within 6-2+9 kpc of the Galactic centre approximately 0.6 Gyr ago. This very small perigalacticon can naturally explain the violent tidal destruction of the dwarf galaxy in the Milky Way's gravitational potential, inducing its transformation into a stellar stream.

Simultaneous determination of 19 flavonoids in commercial trollflowers by using high-performance liquid chromatography and classification of samples by hierarchical clustering analysis.

PubMed

Song, Zhiling; Hashi, Yuki; Sun, Hongyang; Liang, Yi; Lan, Yuexiang; Wang, Hong; Chen, Shizhong

2013-12-01

The flowers of Trollius species, named Jin Lianhua in Chinese, are widely used traditional Chinese herbs with vital biological activity that has been used for several decades in China to treat upper respiratory infections, pharyngitis, tonsillitis, and bronchitis. We developed a rapid and reliable method for simultaneous quantitative analysis of 19 flavonoids in trollflowers by using high-performance liquid chromatography (HPLC). Chromatography was performed on Inertsil ODS-3 C18 column, with gradient elution methanol-acetonitrile-water with 0.02% (v/v) formic acid. Content determination was used to evaluate the quality of commercial trollflowers from different regions in China, while three Trollius species (Trollius chinensis Bunge, Trollius ledebouri Reichb, Trollius buddae Schipcz) were explicitly distinguished by using hierarchical clustering analysis. The linearity, precision, accuracy, limit of detection, and limit of quantification were validated for the quantification method, which proved sensitive, accurate and reproducible indicating that the proposed approach was applicable for the routine analysis and quality control of trollflowers. © 2013.

[Textual criticism and discrimination on the naming of"Five-abstention Soup of Medical Professional"from the Han-tomb of the Marquis of Haihun].

PubMed

Wang, Y R; Yuan, Y; Xu, C Q; Cao, L J; Wang, Y L; Huang, L Q

2017-05-28

A lacquer vessel with the inscription of Yi gong wu jin tang (Five-abstention Soup of Medical Profession) has been unearthed from the Han-tomb of Marquis of Haihun, in which"Five abstentions"is related to the incantations and abstention therapies prevalent in the Qin and Han Dynasties. The"Five-abstention Law"is the five rituals and methods during the process of practicing incantations and abstentions therapies including"keeping one's thinking ( cun si )","holding the breath( bi qi )","twirling eyes ( nian mu )","stepping after Yu's sample ( yu bu )"and"incanting and blessing ( zhou zhu )". The"Five-abstention Law"uses the medium"soup"to achieve the purpose of treatment."Soup"refers either to"decoction"or to"magic water". The lacquer vessel with the inscription"Five-abstention Soup of Medical professional"could be an instrument for implementing the process of practising the"Five-abstention Law", reflecting the historical facts that Liu He, the Marquis Haihun did accept the incantations and abstention therapies.

The Neuropsychology of Risky Sexual Behavior.

PubMed

Ross, J Megan; Duperrouzel, Jacqueline; Vega, Melanie; Gonzalez, Raul

2016-07-01

Engagement in risky sexual behavior (RSB) is a significant public health concern. A growing body of literature is elucidating the role of brain systems and neuropsychological constructs implicated in RSB, which may pave the way for novel insights and prevention efforts. In this article, we review studies incorporating neuropsychology into the study of RSB across the lifespan. The review of the literature on the neuropsychology of RSB is separated into three different sections by age of participants. Background is presented on research associating RSB with neurocognitive processes and the brain systems involved. Given the overlap between RSBs and substance use, studies addressing these problems in tandem are also discussed. Neurocognitive constructs are implicated in RSB, including impulsivity, decision-making, and working memory. Thus far, evidence suggest that neuropsychological factors are associated with engagement in RSB. More research on the influence of neuropsychological factors on engagement in RSB is necessary and may help inform future prevention efforts. (JINS, 2016, 22, 586-594).

Study on the transformed strategy of “life field” for aged in coal mine community——A case sstudy of ccommunity rrenewal ddesign of Sihe coal mine in Jincheng, Shanxi

NASA Astrophysics Data System (ADS)

Xue, Minghui; Wang, Chenghao; Zhang, Shanshan

2017-06-01

Coal mine community is driven by the coal mine industry, and it mainly relies on coal mining enterprises to provide benefits for residents. Under the background of increasing serious global aging problem, the problems in the field of elderly people’s health, life, entertainment, communication, retirement and re-employment and other aspects become more acute and urgently to be solved. So it is necessary to make a more detailed study on how to transform the coal mine community according to the special needs of the elderly miners. This article takes renewal design of SiHe coal mine in JinCheng of ShanXi province as an example and takes the community’s “life field” as a clue, trying to put forward the transformed strategy of “life field” for aged in coal mine community and to come up with a method to update the community throughout the whole atmosphere to the personal space.

Physical Parameters, Modeling, and Methodological Details in Using IR Laser Pulses to Warm Frozen or Vitrified Cells Ultra-Rapidly†

PubMed Central

Kleinhans, F.W.; Mazur, Peter

2015-01-01

We report additional details of the thermal modeling, selection of the laser, and construction of the Cryo Jig used for our ultra-rapid warming studies of mouse oocytes (B Jin, FW Kleinhans, Peter Mazur, Cryobiology 68 (2014) 419–430). A Nd:YAG laser operating at 1064 nm was selected to deliver short 1 msec pulses of sufficient power to produce a warming rate of 1 × 107 °C/min from –190°C to 0°C. A special Cryo Jig was designed and built to rapidly remove the sample from LN2 and expose it to the laser pulse. India ink carbon black particles were required to increase the laser energy absorption of the sample. The thermal model reported here is more general than that previously reported. The modeling reveals that the maximum warming rate achievable via external warming across the cell membrane is proportional to (1/R2) where R is the cell radius. PMID:25724528

Comparisons of synthesized and individual reinforcement contingencies during functional analysis.

PubMed

Fisher, Wayne W; Greer, Brian D; Romani, Patrick W; Zangrillo, Amanda N; Owen, Todd M

2016-09-01

Researchers typically modify individual functional analysis (FA) conditions after results are inconclusive (Hanley, Iwata, & McCord, 2003). Hanley, Jin, Vanselow, and Hanratty (2014) introduced a marked departure from this practice, using an interview-informed synthesized contingency analysis (IISCA). In the test condition, they delivered multiple contingencies simultaneously (e.g., attention and escape) after each occurrence of problem behavior; in the control condition, they delivered those same reinforcers noncontingently and continuously. In the current investigation, we compared the results of the IISCA with a more traditional FA in which we evaluated each putative reinforcer individually. Four of 5 participants displayed destructive behavior that was sensitive to the individual contingencies evaluated in the traditional FA. By contrast, none of the participants showed a response pattern consistent with the assumption of the IISCA. We discuss the implications of these findings on the development of accurate and efficient functional analyses. © 2016 Society for the Experimental Analysis of Behavior.

Nonequilibrium hypersonic flows simulations with asymptotic-preserving Monte Carlo methods

NASA Astrophysics Data System (ADS)

Ren, Wei; Liu, Hong; Jin, Shi

2014-12-01

In the rarefied gas dynamics, the DSMC method is one of the most popular numerical tools. It performs satisfactorily in simulating hypersonic flows surrounding re-entry vehicles and micro-/nano- flows. However, the computational cost is expensive, especially when Kn → 0. Even for flows in the near-continuum regime, pure DSMC simulations require a number of computational efforts for most cases. Albeit several DSMC/NS hybrid methods are proposed to deal with this, those methods still suffer from the boundary treatment, which may cause nonphysical solutions. Filbet and Jin [1] proposed a framework of new numerical methods of Boltzmann equation, called asymptotic preserving schemes, whose computational costs are affordable as Kn → 0. Recently, Ren et al. [2] realized the AP schemes with Monte Carlo methods (AP-DSMC), which have better performance than counterpart methods. In this paper, AP-DSMC is applied in simulating nonequilibrium hypersonic flows. Several numerical results are computed and analyzed to study the efficiency and capability of capturing complicated flow characteristics.

Split-plot microarray experiments: issues of design, power and sample size.

PubMed

Tsai, Pi-Wen; Lee, Mei-Ling Ting

2005-01-01

This article focuses on microarray experiments with two or more factors in which treatment combinations of the factors corresponding to the samples paired together onto arrays are not completely random. A main effect of one (or more) factor(s) is confounded with arrays (the experimental blocks). This is called a split-plot microarray experiment. We utilise an analysis of variance (ANOVA) model to assess differentially expressed genes for between-array and within-array comparisons that are generic under a split-plot microarray experiment. Instead of standard t- or F-test statistics that rely on mean square errors of the ANOVA model, we use a robust method, referred to as 'a pooled percentile estimator', to identify genes that are differentially expressed across different treatment conditions. We illustrate the design and analysis of split-plot microarray experiments based on a case application described by Jin et al. A brief discussion of power and sample size for split-plot microarray experiments is also presented.

Water use efficiency and integrated water resource management for river basin

NASA Astrophysics Data System (ADS)

Deng, Xiangzheng; Singh, R. B.; Liu, Junguo; Güneralp, Burak

Water use efficiency and management have attracted increasing attention as water has become scare to challenge the world's sustainable development. Water use efficiency is correlated to the land use and cover changes (LUCC), population distribution, industrial structure, economic development, climate changes, and environmental governance. These factors significantly alter water productivity for water balance through the changes in natural environment and socio-economic system (Wang et al., 2015b). Consequently, dynamics of water inefficiency lower the social welfare of water allocation (Wang et al., 2015b), and induce water management alternation interactively and financially (Wang et al., 2015a). This triggers on actual water price changes through both natural resource and socioeconomic system (Zhou et al., 2015). Therefore, it is very important to figure out a mechanism of water allocation in the course of LUCC (Jin et al., 2015) at a global perspective (Zhao et al., 2015), climate and economic changes of ecosystem service at various spatial and temporal scales (Li et al., 2015).

Making a molecular gas in the quantum regime

NASA Astrophysics Data System (ADS)

Ni, Kang-Kuen

2017-04-01

Ultracold molecules are exciting systems for a large range of scientific explorations including studies of novel phases of matter and precision measurement. In this talk, I will present a brief story of the first quantum gas of molecules, KRb, created under my PhD advisor, Deborah Jin, in 2008. A complete surprise was finding ultracold chemistry in such a system through measurements of reactant losses. In particular, long-range physics that determines KRb reactant collision rates, including van der Waals interactions, quantum statistics, and dipolar interactions, were studied extensively. However, the short-range behavior of these chemical reactions remains unknown. A legacy of her work is carried out in my lab at Harvard, where we are integrating physical chemistry tools with cold atom techniques to study ultracold chemistry with KRb molecules. In particular, we aim to elucidate the four-center reaction 2 KRb ->K2 + Rb2 by detecting the reaction products through ionization - both identify the product species and mapping out their complete quantum states.

PandaX-III neutrinoless double beta decay experiment

NASA Astrophysics Data System (ADS)

Wang, Shaobo; PandaX-III Collaboration

2017-09-01

The PandaX-III experiment uses high pressure Time Projection Chambers (TPCs) to search for neutrinoless double-beta decay of Xe-136 with high energy resolution and sensitivity at the China Jin-Ping underground Laboratory II (CJPL-II). Fine-pitch Microbulk Micromegas will be used for charge amplification and readout in order to reconstruct both the energy and track of the neutrinoless double-beta decay event. In the first phase of the experiment, the detector, which contains 200 kg of 90% Xe-136 enriched gas operated at 10 bar, will be immersed in a large water tank to ensure 5 m of water shielding. For the second phase, a ton-scale experiment with multiple TPCs will be constructed to improve the detection probability and sensitivity. A 20-kg scale prototype TPC with 7 Micromegas modules has been built to optimize the design of Micromegas readout module, study the energy calibration of TPC and develop algorithm of 3D track reconstruction.

Iron intake and body iron stores, anaemia and risk of hyperglycaemia among Chinese adults: the prospective Jiangsu Nutrition Study (JIN).

PubMed

Shi, Zumin; Zhou, Minghao; Yuan, Baojun; Qi, Lu; Dai, Yue; Luo, Yazhou; Holmboe-Ottesen, Gerd

2010-09-01

Fe supplementation has been used to prevent anaemia in China; however, high Fe intake and body Fe stores may increase diabetes risk. The present study aimed to prospectively examine the association between Fe intake/stores and hyperglycaemia, and to assess the joint effects on anaemia. We followed 1056 healthy adults aged 20 years and older from 2002 to 2007. Body Fe stores were measured. Dietary data were collected using a 3 d food record and FFQ. Hyperglycaemia was defined as fasting plasma glucose >5.6 mmol/l. Of the participants, 28.8 % were anaemic at baseline. During the 5 years of follow-up, we documented 125 incident cases of hyperglycaemia, among them twenty-three were diabetic. Haem Fe intake was positively associated with the risk of hyperglycaemia in men and women: the OR (95 % CI) across increasing quartiles of haem Fe intake was 1.00 (referent), 1.49 (0.74, 3.01), 2.16 (1.06, 4.42) and 3.48 (1.71, 7.11), respectively (P for trend <0.001). Comparing the fourth quartile of serum ferritin with the others, the age- and gender-adjusted OR (95 % CI) was 1.54 (1.01, 2.34), P for trend = 0.043. The association between total Fe intake and the risk of hyperglycaemia was significant in men (P for trend = 0.002). Anaemia added additional risk of hyperglycaemia on haem Fe intake. Comparing extreme quartiles of haem Fe intake, the OR (95 % CI) was 5.67 (1.43, 22.49) and 3.44 (1.51, 7.85) for hyperglycaemia among anaemic and non-anaemic participants (P for trend = 0.008 and 0.010, respectively). The present cohort study suggests that high haem Fe intake, anaemia and high ferritin are associated with an increased risk of hyperglycaemia in Chinese men and women. There was a joint effect between anaemia and haem Fe intake on the risk of hyperglycaemia.

Qi-Dan Fang ameliorates adriamycin-induced nephrotic syndrome rat model by enhancing renal function and inhibiting podocyte injury.

PubMed

Wu, Jun-Biao; Ye, Shu-Fang; Liang, Chun-Ling; Li, Yu-Cui; Yu, Ying-Jia; Lai, Jie-Mei; Lin, Hui; Zheng, Jie; Zhou, Jiu-Yao

2014-02-12

Nephrotic syndrome (NS) is a clinical syndrome with a variety of causes, mainly characterized by heavy proteinuria. Podocyte injury plays a key role in proteinuria, one of the principal means for the control of NS is to prevent podocyte injury. Qi-Dan Fang consists of two of the most extensively applied herbal remedies among Traditional Chinese Medicine (TCM) (Radix Astragali Mongolici and Radix Salviae Miltiorrhizae, with a weight ratio of 5:1) which are specifically used for the treatment of various kidney diseases. In previous studies, we found that Qi-Dan Fang provides improvement to patients with adriamycin-induced nephrotic syndrome by alleviating proteinuria and serum lipid. The aim of this study is to study the efficiency of Qi-Dan Fang on NS model rat with renal dysfunction and podocyte injury, something which has not been carried out yet. The rats were divided into Normal, Model, Jin Gui Shen Qi Pill (4.12 g/kg), Qi-Dan Fang (3.09, 6.17 and 12.34 g/kg/d) groups, they were each given a single tail intravenous injection of Adriamycin (6.0 mg/kg) except for the Normal group and were orally administered dosages of Qi-Dian Fang and Jin Gui Shen Qi pills once daily for 7 weeks. Following the treatment, the content of cystation C (CysC), blood urea nitrogen (BUN), serum creatinine (Scr) were measured with an autobiochemical analyser. The pathomorphological changes to the glomeruli, the mRNA expressions of nephrin, podocin, CD2AP genes and p53, bax, bcl-2 proteins expressions were also carried out to probe the effects of Qi-Dan Fang. (1) Qi-Dan Fang treatment raised the level of CysC in blood serum while lowering the content of BUN and Scr in the adriamycin-induced nephrotic syndrome rat model; (2) Long-term administration of Qi-Dan Fang was able to ameliorate pathomorphological change of glomeruli and repair the organization structure of Glomerulus; (3) Qi-Dan Fang could increase the mRNA expression of nephrin, podocin and CD2AP genes, down-regulate the

Final Report for EPSCoR Implementation Award DE-FG02-08ER46528 to University of Tennessee

DOE Office of Scientific and Technical Information (OSTI.GOV)

Egami, Takeshi

) and the other in soft matter sciences (bio-membranes). Through this project we promoted the use of neutron scattering, particularly in biological and life sciences and in energy sciences, and facilitated the DOE investment in this field to impact wide fields of science and engineering. This project was administered through the Joint Institute for Neutron Sciences (JINS) of the University of Tennessee (UT) and ORNL. JINS is jointly supported by both UT and ORNL, and participate in organizing workshops and schools to promote the use of neutron scattering.« less

Brunhes-Matuyama Magnetic Polarity Reversal Tracing using Chinese loess10Be

NASA Astrophysics Data System (ADS)

Zhou, W.; Beck, W.; Kong, X.; An, Z.; Qiang, X.; Wu, Z.; Xian, F.; Ao, H.

2014-12-01

The geomagnetic polarity reversal is generally considered to occur synchronously around the world, and is commonly used as a time marker. However, in the case of the most recent reversal, the Brunhes-Matuyama (B-M) reversal (~780 ka), comparison of paleomagnetic studies in Chinese loess-paleosol sequences versus marine sediments revealed a marked discrepancy in timing of this event (Tauxe et al., 1996; Zhou and Shackleton, 1999), leading to the debate on uncertainties of paleoclimatic correlation between the Chinese loess-paleosol sequences and marine sediments (Wang et al., 2006; Liu et al., 2008; Jin and Liu, 2011). Based on this issue, here we propose to use the cosmogenic 10Be to address this conundrum. 10Be is a long-lived radionuclide produced in the atmosphere by cosmic ray spallation reactions and carried to the ground attached to aerosols. Its atmospheric production rate is inversely proportional to the geomagnetic field intensity (Masarik and Beer, 1999). This allows us to reconstruct past geomagnetic field intensity variations using 10Be concentrations recorded in different sedimentary archives. We carried out the 10Be studies in Luochuan and Xifeng sections in Chinese Loess Plateau, both loess profiles show that 10Be production rate was at a maximum-an indication of the dipole field reversal-at ca. 780 ± 3 ka BP., in paleosol unit S7corresponding to MIS 19. These results have proven that the timing of B-M reversal recorded in Chinese loess is synchronous with that seen in marine records (Tauxe et al., 1996) and reaffirmed the conventional paleoclimatic correlation of loess-paleosol sequences with marine isotope stages and the standard loess timescale as correct. However, it is ~25 ka younger than the age (depth) of the magnetic polarity reversal recorded in these same Chinese loess-paleosol sequences, demonstrating that loess magnetic overprinting has occurred. 1.Jin, C.S.,et al., 2011,PALAEOGEOGR PALAEOCL, 299, 309-3172.Liu, Q.S., et al., 2008, EARTH

Can attenuation of attentional blink also evoke removal of repetition blindness?

PubMed

Choi, Hoon; Watanabe, Takeo

2014-06-01

A recent study showed that attentional blink (AB), which has been considered to reflect the capacity limitation of visual temporal attention, can be attenuated after a short period of the color-salient training, in which the second target (T2) within the AB period is given a salient color (Choi et al., 2012). The current study explored whether the effect of the color-salient training could be transferred to another phenomenon. In addition to AB, repetition blindness (RB) was employed, which is phenomenologically similar to, but fundamentally different from AB. After completion of the color-salient training with a nonrepeated T2 (corresponding to AB), RB was still observed, whereas AB was completely removed. However, the color-salient training with a repeated T2 (similar to RB) induced not only a significant reduction of RB but also an attenuation of AB. This result provides further evidence for dissociation between AB and RB. In addition, it implies that the color-salient training improves the attentional control mechanism related to target-distractor discrimination rather than to the perceptual system. Copyright © 2014 Elsevier Ltd. All rights reserved.

Clouds not important for control of short-term surface temperatures

NASA Astrophysics Data System (ADS)

Schultz, Colin

2012-01-01

In two recent papers, R. W. Spencer and W. D. Braswell (Remote Sens., 3(8), 1603- 1613, doi:10.3390/rs3081603, 2011) (SB) and R. S. Lindzen and Y.-S. Choi (Asia Pac. J. Atmos. Sci., 47(4), 377-390, doi:10.1007/s13143-011-0023-x, 2011) (LC) argue that clouds act as a primary initiator of surface temperature changes in Earth's climate system. The two sets of authors reached this conclusion by developing a method that tries to determine the Earth's surface temperature by calculating how much energy is stored in the ocean's upper layers, how much of this heat is transferred to the rest of the climate system, how clouds affect the rate at which energy escapes Earth's atmosphere, and how the surface's energy flux changes with temperature. Both studies spurred substantial debate within the media and the public, with the research by SB causing the editor of the journal in which it was published to resign, claiming it should not have been accepted by the journal. Assessing the two studies, Dessler found what he suggests are a number of methodological errors.

Absence of the right common carotid artery: a rare case without separate origins of the internal and external carotid arteries.

PubMed

Quinones, Gretchen; Srinivasan, Ashok

Absence of the common carotid artery (CCA) is a rare anomaly. In the few cases described in the literature, it has been typically associated with separate origins of the internal carotid artery (ICA) and external carotid artery (ECA) Fife (1921), Boyd (1934), Rossiti and Raininko (2001), Cerase et al. (2009), Drazin et al. (2010), Yim et al. (2009), Monaco et al. (2009), Jerius et al. (1995), Dahn et al. (1999), Cakirer et al. (2002), Choi et al. (2015), Bryan et al. (1978), Horowitz et al. (2003), Roberts and Gerald (1978), Rajeshwari (2013), Purkayastha et al. (2006), Maybody et al. (2003), Wood et al. (2011) . To the best of our knowledge, absence of the CCA without separate origins of the ECA and ICA has only been described five times before, one of them in conjunction with a persistent proatlantal intersegmental artery (PIA) Cao et al. (2011) and four with agenesis of the ICA Kobayashi et al. (2013), Kunishio et al. (1987), Chen et al. (2008), Xie et al. (2010) . We present a case of a previously undescribed variation of this rare vascular anomaly. Copyright © 2017 Elsevier Inc. All rights reserved.

Lepton electric dipole moment and strong CP violation

NASA Astrophysics Data System (ADS)

Ghosh, Diptimoy; Sato, Ryosuke

2018-02-01

Contribution of the strong CP angle, θ bar , to the Wilson Coefficients of electron and muon electric dipole moment (EDM) operators are discussed. Previously, θ bar contribution to the electron EDM operator was calculated by Choi and Hong [1]. However, the effect of CP-violating three meson coupling was missing in [1]. We include this missing contribution for the first time in the literature, and reevaluate the Wilson coefficients of the lepton EDM operator. We obtain de = - (2.2 - 8.6) ×10-28 θ bar e-cm which is 15-70% of the result obtained in [1]. We also estimated the muon EDM as dμ = - (0.5 - 1.8) ×10-25 θ bar e-cm. Using | θ bar | ≲10-10 suggested by the neutron EDM measurements, we obtain |de | ≲ 8.6 ×10-38e-cm and |dμ | ≲ 1.8 ×10-35e-cm. The θ bar contribution to the muon EDM is much below the sensitivities of the current and near future experiments. Our result shows that the θ bar contribution to de,μ can be larger than the CKM contributions by many orders of magnitude.

NHE10, a novel osteoclast-specific member of the Na{sup +}/H{sup +} exchanger family, regulates osteoclast differentiation and survival

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lee, Seoung Hoon; Kim, Taesoo; Park, Eui-Soon

2008-05-02

Bone homeostasis is tightly regulated by the balanced actions of osteoblasts (OBs) and osteoclasts (OCs). We previously analyzed the gene expression profile of OC differentiation using a cDNA microarray, and identified a novel osteoclastogenic gene candidate, clone OCL-1-E7 [J. Rho, C.R. Altmann, N.D. Socci, L. Merkov, N. Kim, H. So, O. Lee, M. Takami, A.H. Brivanlou, Y. Choi, Gene expression profiling of osteoclast differentiation by combined suppression subtractive hybridization (SSH) and cDNA microarray analysis, DNA Cell Biol. 21 (2002) 541-549]. In this study, we have isolated full-length cDNAs corresponding to this clone from mice and humans to determine the functionalmore » roles of this gene in osteoclastogenesis. The full-length cDNA of OCL-1-E7 encodes 12 membrane-spanning domains that are typical of isoforms of the Na{sup +}/H{sup +} exchangers (NHEs), indicating that this clone is a novel member of the NHE family (hereafter referred to as NHE10). Here, we show that NHE10 is highly expressed in OCs in response to receptor activator of nuclear factor-{kappa}B ligand signaling and is required for OC differentiation and survival.« less

Application of mean wall shear stress boundary condition to complex turbulent flows using a wall-modeled large eddy simulation

NASA Astrophysics Data System (ADS)

Cho, Minjeong; Lee, Jungil; Choi, Haecheon

2012-11-01

The mean wall shear stress boundary condition was successfully applied to turbulent channel and boundary flows using large eddy simulation without resolving near-wall region (see Lee, Cho & Choi in this book of abstracts). In the present study, we apply this boundary condition to more complex flows where flow separation and redeveloping flow exist. As a test problem, we consider flow over a backward-facing step at Reh = 22860 based on the step height. Turbulent boundary layer flow at the inlet (Reθ = 1050) is obtained using inflow generation technique by Lund et al. (1998) but with wall shear stress boundary condition. First, we prescribe the mean wall shear stress distribution obtained from DNS (Kim, 2011, Ph.D. Thesis, Stanford U.) as the boundary condition of present simulation. Here we give no-slip boundary condition at flow-reversal region. The present results are in good agreements with the flow statistics by DNS. Currently, a dynamic approach of obtaining mean wall shear stress based on the log-law is being applied to the flow having flow separation and its results will be shown in the presentation. Supported by the WCU and NRF programs.

How The Fault in Our Stars illuminates four themes of the Adolescent End of Life Narrative.

PubMed

Kirkman, Anna Obergfell; Hartsock, Jane A; Torke, Alexia M

2018-05-26

Adolescents who face life-limiting illness have unique developmental features and strong personal preferences around end of life (EOL) care. Understanding and documenting those preferences can be enhanced by practising narrative medicine. This paper aims to identify a new form of narrative, the Adolescent End of Life Narrative, and recognise four central themes. The Adolescent EOL Narrative can be observed in young adult fiction, The Fault in Our Stars , which elucidates the notion that terminally ill adolescents have authentic preferences about their life and death. Attaining narrative competence and appreciating the distinct perspective of the dying adolescent allows medical providers and parents to support the adolescent in achieving a good death. By thinking with the Adolescent EOL Narrative, adults can use Voicing my CHOiCES, an EOL planning guide designed for adolescents, to effectively capture the adolescent's preferences, and the adolescent can make use of this type of narrative to make sense of their lived experience. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Absolute continuity for operator valued completely positive maps on C∗-algebras

NASA Astrophysics Data System (ADS)

Gheondea, Aurelian; Kavruk, Ali Şamil

2009-02-01

Motivated by applicability to quantum operations, quantum information, and quantum probability, we investigate the notion of absolute continuity for operator valued completely positive maps on C∗-algebras, previously introduced by Parthasarathy [in Athens Conference on Applied Probability and Time Series Analysis I (Springer-Verlag, Berlin, 1996), pp. 34-54]. We obtain an intrinsic definition of absolute continuity, we show that the Lebesgue decomposition defined by Parthasarathy is the maximal one among all other Lebesgue-type decompositions and that this maximal Lebesgue decomposition does not depend on the jointly dominating completely positive map, we obtain more flexible formulas for calculating the maximal Lebesgue decomposition, and we point out the nonuniqueness of the Lebesgue decomposition as well as a sufficient condition for uniqueness. In addition, we consider Radon-Nikodym derivatives for absolutely continuous completely positive maps that, in general, are unbounded positive self-adjoint operators affiliated to a certain von Neumann algebra, and we obtain a spectral approximation by bounded Radon-Nikodym derivatives. An application to the existence of the infimum of two completely positive maps is indicated, and formulas in terms of Choi's matrices for the Lebesgue decomposition of completely positive maps in matrix algebras are obtained.

Gyrokinetic simulation study of magnetic island effects on neoclassical physics and micro-instabilities in a realistic KSTAR plasma

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kwon, Jae-Min; Ku, S.; Choi, M. J.

Here, we perform gyrokinetic simulations to study the effects of a stationary magnetic island on neoclassical flow and micro-instability in a realistic KSTAR plasma condition. Through the simulations, we aim to analyze a recent KSTAR experiment, which was to measure the details of poloidal flow and fluctuation around a stationary (2, 1) magnetic island [M. J. Choi et al., Nucl. Fusion 57, 126058 (2017)]. From the simulations, it is found that the magnetic island can significantly enhance the equilibrium E x B flow. The corresponding flow shearing is strong enough to suppress a substantial portion of ambient micro-instabilities, particularly ∇Tmore » e-driven trapped electron modes. This implies that the enhanced E x B flow can sustain a quasi-internal transport barrier for T e in an inner region neighboring the magnetic island. The enhanced E x B flow has a (2, 1) mode structure with a finite phase shift from the mode structure of the magnetic island. It is shown that the flow shear and the fluctuation suppression patterns implied from the simulations are consistent with the observations on the KSTAR experiment.« less

Gyrokinetic simulation study of magnetic island effects on neoclassical physics and micro-instabilities in a realistic KSTAR plasma

DOE PAGES

Kwon, Jae-Min; Ku, S.; Choi, M. J.; ...

2018-05-01

Here, we perform gyrokinetic simulations to study the effects of a stationary magnetic island on neoclassical flow and micro-instability in a realistic KSTAR plasma condition. Through the simulations, we aim to analyze a recent KSTAR experiment, which was to measure the details of poloidal flow and fluctuation around a stationary (2, 1) magnetic island [M. J. Choi et al., Nucl. Fusion 57, 126058 (2017)]. From the simulations, it is found that the magnetic island can significantly enhance the equilibrium E x B flow. The corresponding flow shearing is strong enough to suppress a substantial portion of ambient micro-instabilities, particularly ∇Tmore » e-driven trapped electron modes. This implies that the enhanced E x B flow can sustain a quasi-internal transport barrier for T e in an inner region neighboring the magnetic island. The enhanced E x B flow has a (2, 1) mode structure with a finite phase shift from the mode structure of the magnetic island. It is shown that the flow shear and the fluctuation suppression patterns implied from the simulations are consistent with the observations on the KSTAR experiment.« less

Improvement of aquaponic performance through micro- and macro-nutrient addition.

PubMed

Ru, Dongyun; Liu, Jikai; Hu, Zhen; Zou, Yina; Jiang, Liping; Cheng, Xiaodian; Lv, Zhenting

2017-07-01

Aquaponics is one of the "zero waste" industry in the twenty-first century, and is considered to be one of the major trends for the future development of agriculture. However, the low nitrogen utilization efficiency (NUE) restricted its widely application. To date, many attempts have been conducted to improve its NUE. In the present study, effect of micro- and macro-nutrient addition on performance of tilapia-pak choi aquaponics was investigated. Results showed that the addition of micro- and macro-nutrients improved the growth of plant directly and facilitated fish physiology indirectly, which subsequently increased NUE of aquaponics from 40.42 to 50.64%. In addition, remarkable lower total phosphorus concentration was obtained in aquaponics with micro- and macro-nutrient addition, which was attributed to the formation of struvite. Most of the added micro-nutrients were enriched in plant root, while macro-nutrients mainly existed in water. Moreover, no enrichment of micro- and macro-nutrients in aquaponic products (i.e., fish and plant leaves) was observed, indicating that it had no influence on food safety. The findings here reported manifest that appropriate addition of micro- and macro-nutrients to aquaponics is necessary, and would improve its economic feasibility.

Understanding Superfluid ^3He by Determining β-Coefficients of Ginzburg-Landau Theory

NASA Astrophysics Data System (ADS)

Choi, H.; Davis, J. P.; Pollanen, J.; Halperin, W. P.

2007-03-01

The Ginzburg-Landau (GL) theory is a phenomenological theory that is used to characterize thermodynamic properties of a system near a phase transition. The free energy is expressed as an expansion of the order parameter and for superfluid ^3He there is one second order term and five fourth order terms. Since the GL theory is a phenomenological theory, one can determine the coefficients to these terms empirically; however, existing experiments are unable to determine all five fourth order coefficients, the β's. To date, only four different combinations of β's are known [1]. In the case of supeprfluid ^3He, using quasiclassical theory, the coefficients have been calculated [2]. We used the calculation as a guide to construct a model to define all five β's independently. The model provides us with the full understanding of the GL theory for ^3He, which is useful in understanding various superfluid phases of both bulk ^3He and disordered ^3He in aerogel. [1] H. Choi et al., J. Low Temp. Phys., submitted; http://arxiv.org/abs/cond-mat/0606786. [2] J.A. Sauls and J.W. Serene, Phys. Rev. B 24, 183 (1981).

Characteristics of tip-leakage flow in an axial fan

NASA Astrophysics Data System (ADS)

Park, Keuntae; Choi, Haecheon; Choi, Seokho; Sa, Yongcheol

2014-11-01

An axial fan with a shroud generates complicated vortical structures by the interaction of the axial flow with the fan blades and shroud near the blade tips. Large eddy simulation (LES) is performed for flow through a forward-swept axial fan, operating at the design condition of Re = 547,000 based on the radius of blade tip and the tip velocity. A dynamic global model (Lee et al. 2010) is used for a subgrid-scale model, and an immersed boundary method in a non-inertial reference frame (Kim & Choi 2006) is adopted for the present simulation. It is found that two vortical structures are formed near the blade tip: the main tip leakage vortex (TLV) and the auxiliary TLV. The main TLV is initiated near the leading edge, develops downstream, and impinges on the pressure surface of the next blade, where the pressure fluctuations and turbulence intensity become high. On the other hand, the auxiliary TLV is initiated at the aft part of the blade but is relatively weak such that it merges with the main TLV. Supported by the KISTI Supercomputing Center (KSC-2014-C2-014).

Effects of inertia on the steady shear rheology of concentrated emulsions: sign reversal of normal stress differences

NASA Astrophysics Data System (ADS)

Srivastava, Priyesh; Sarkar, Kausik

2012-11-01

The shear rheology of moderately concentrated emulsions (5-27% volume fraction) in the presence of inertia is numerically investigated. Typically, an emulsion of viscous drops experiences positive first normal stress difference (N1) and negative second normal stress difference (N2) , as has also been predicted by perturbative analysis (Choi-Schowalter model) and numerical simulation. However, recently using single drop results we have shown [Li and Sarkar, 2005, J. Rheo, 49, 1377] that introduction of inertia reverses the signs of the normal stress difference in the dilute limit. Here, we numerically investigate the effects of interactions between drops in a concentrated system. The simulation is validated against the dilute results as well as analytical relations. It also shows the reversal of signs for N1 and N2 for small Capillary numbers above a critical Reynolds number. The physics is explained by the inertia-induced orientation of the individual drops in shear. Increasing volume fraction increases the critical Reynolds number at which N1 and N2change sign. The breakdown of linearity with volume fraction with increasing concentration is also analyzed. Partially supported by NSF.

Operational validation of a multi-period and multi-criteria model conditioning approach for the prediction of rainfall-runoff processes in small forest catchments

NASA Astrophysics Data System (ADS)

Choi, H.; Kim, S.

2012-12-01

Most of hydrologic models have generally been used to describe and represent the spatio-temporal variability of hydrological processes in the watershed scale. Though it is an obvious fact that hydrological responses have the time varying nature, optimal values of model parameters were normally considered as time invariants or constants in most cases. The recent paper of Choi and Beven (2007) presents a multi-period and multi-criteria model conditioning approach. The approach is based on the equifinality thesis within the Generalised Likelihood Uncertainty Estimation (GLUE) framework. In their application, the behavioural TOPMODEL parameter sets are determined by several performance measures for global (annual) and short (30-days) periods, clustered using a Fuzzy C-means algorithm, into 15 types representing different hydrological conditions. Their study shows a good performance on the calibration of a rainfall-runoff model in a forest catchment, and also gives strong indications that it is uncommon to find model realizations that were behavioural over all multi-periods and all performance measures, and multi-period model conditioning approach may become new effective tool for predictions of hydrological processes in ungauged catchments. This study is a follow-up study on the Choi and Beven's (2007) model conditioning approach to test how the approach is effective for the prediction of rainfall-runoff responses in ungauged catchments. To achieve this purpose, 6 small forest catchments are selected among the several hydrological experimental catchments operated by Korea Forest Research Institute. In each catchment, long-term hydrological time series data varying from 10 to 30 years were available. The areas of the selected catchments range from 13.6 to 37.8 ha, and all areas are covered by coniferous or broad-leaves forests. The selected catchments locate in the southern coastal area to the northern part of South Korea. The bed rocks are Granite gneiss, Granite or