Sample records for john alexander williams

  1. Conversations with John Williams

    ERIC Educational Resources Information Center

    Sullivan, Jack

    2007-01-01

    In this article, the author shares the views of John Williams, Hollywood's premier composer, who has written more than 300 scores, about the future of classical and film music. A gregarious person in a field requiring monklike isolation, Williams values the "association with the soloists, and the wonderful inspiration from players." His…

  2. John Dewey, William Wirt and the Gary Schools Plan: A Centennial Reappraisal

    ERIC Educational Resources Information Center

    Thorburn, Malcolm

    2017-01-01

    A century on from the height of John Dewey's educational writings and the reputation of the Gary Schools Plan as a model of progressive education, the paper reappraises two key matters: the relationship between John Dewey and William Wirt, the first superintendent of the Gary Schools in Gary Indiana, and the coherence between John Dewey's…

  3. Finding revelation in anthropology: Alexander Winchell, William Robertson Smith and the heretical imperative.

    PubMed

    Livingstone, David N

    2015-09-01

    Anthropological inquiry has often been considered an agent of intellectual secularization. Not least is this so in the sphere of religion, where anthropological accounts have often been taken to represent the triumph of naturalism. This metanarrative, however, fails to recognize that naturalistic explanations could sometimes be espoused for religious purposes and in defence of confessional creeds. This essay examines two late nineteenth-century figures--Alexander Winchell in the United States and William Robertson Smith in Britain--who found in anthropological analysis resources to bolster rather than undermine faith. In both cases these individuals found themselves on the receiving end of ecclesiastical censure and were dismissed from their positions at church-governed institutions. But their motivation was to vindicate divine revelation, in Winchell's case from the physical anthropology of human origins and in Smith's from the cultural anthropology of Semitic ritual.

  4. Love and Work: A Reading of John Williams' "Stoner"

    ERIC Educational Resources Information Center

    Frank, Jeff

    2017-01-01

    This article offers a close reading of the novel Stoner by John Williams. "Stoner," and not the countless reports and jeremiads on teaching, helps us find what we are searching for: a way to live--and talk about--teaching in a dignified and artful way. We need to seek out voices that remind, recall and reveal teaching for the beautifully…

  5. John Dalton and the London atomists: William and Bryan Higgins, William Austin, and new Daltonian doubts about the origin of the atomic theory

    PubMed Central

    Grossman, Mark I.

    2014-01-01

    Most historians have ruled out the possibility that John Dalton was influenced by the theories of atomists William and Bryan Higgins, as well as William Austin, in developing his first table of atomic weights on 6 September 1803. I review and evaluate the case to be made for the influence of each scientist on Dalton. Contrary to prevailing views, I raise new Daltonian doubts, especially for Bryan Higgins.

  6. Report of Some Comets: The Discovery of Uranus and Comets by William, Caroline, and John Herschel

    NASA Astrophysics Data System (ADS)

    Pasachoff, Jay M.; Olson, R. J. M.

    2011-01-01

    We report on the discovery and drawings of comets by William, Caroline, and John Herschel. The first discovery, by William Herschel, in 1781 from Bath, published in the Philosophical Transactions of the Royal Society with the title "Report of a Comet," turned out to be Uranus, the first planet ever discovered, Mercury through Saturn having been known since antiquity. William's sister Caroline was given duties of sweeping the skies and turned out to be a discoverer of 8 comets in her own right, in addition to keeping William's notes. Caroline's comets were discovered from Slough between 1786 and 1797. In the process, we also discuss original documents from the archives of the Royal Society and of the Royal Astronomical Society. We conclude by showing comet drawings that we have recently attributed to John Herschel, including Halley's Comet from 1836, recently located in the Ransom Center of the University of Texas at Austin. Acknowledgments: Planetary astronomy at Williams College is supported in part by grant NNX08AO50G from NASA Planetary Astronomy. We thank Peter Hingley of the Royal Astronomical Society and Richard Oram of the Harry Ransom Center of The University of Texas at Austin for their assistance.

  7. William Henry Welch (1850–1934): the road to Johns Hopkins

    PubMed Central

    2011-01-01

    William Henry Welch's selection in 1884 as the first faculty member of the new medical school at Johns Hopkins created the invigorating atmosphere that generated the revolutionary changes in medical training and laboratory medicine that transformed medicine in America. Dr. Welch's family traditions, his New England upbringing, Yale education, and German university experience prepared a unique individual to lead American medicine into the 20th century. PMID:21738298

  8. The changing assessments of John Snow's and William Farr's cholera studies.

    PubMed

    Eyler, J M

    2001-01-01

    This article describes the epidemiological studies of cholera by two major British investigators of the mid-nineteenth century, John Snow and William Farr, and it asks why the assessments of their results by contemporaries was the reverse of our assessment today. In the 1840s and 1850s Farr's work was considered definitive, while Snow's was regarded as ingenious but flawed. Although Snow's conclusions ran contrary to the exceptations of his contemporaries, the major reservations about his cholera studies concerned his bold use of analogy, his thoroughgoing reductionism, and his willingness to ignore what seemed to be contrary evidence. Farr's electric use of current theories, his reliance multiple causation, and his discovery of a mathematical law to describe the outbreak in London in 1849 was much more convincing to his contemporaries. A major change in thinking about disease causation was needed before Snow's work could be widely accepted. William Farr's later studies contributed to that acceptance.

  9. John Whitridge Williams' contribution to democracy abroad. (The fetus treated as a patient).

    PubMed

    Vasicka, A

    1999-04-01

    The idealism of American pioneers was a driving force in the development of science, democracy, and sociology in the United States. It also served as a model for the development of new democracies abroad. The first American grafted democracy was established in Czechoslovakia in 1918, under Thomas Garrigue Masaryk as President. As a former professor of philosophy, at Charles University in Prague, he built the foundation of Czechoslovakian democracy on the historical principles of Jan Hus' search for the truth (1415), Jan Amos Komensky's use of Science and Humanism (1630), and on the values of American democracy as he conceived it from multiple visits to the United States and from the practical philosophy of his American wife. His major educational means was the use of science. He became a founder of political science. As president he recognized, that democracy, as a state form, does not educate people, they educate themselves through family, school, church, physician and life experience. In the last quarter of the nineteenth century, on the eve of the opening of John Hopkin's University Hospital, a young American scientist by the name John Whitridge Williams came to Prague, Vienna, and other Europeans cities for the purpose of studying scientific obstetrics. He believed in the power of the truth in the power of the truth equally as Masaryk did and used science uncompromisingly in his speciality. He became the founder of American scientific obstetrics. He was shy of political science and ethnic problems. There was no personal connection between Masaryk and Williams. In 1903, John Whitridge Williams published his review of European and American obstetrics: he abolished the craft of obstetrics and worked the science of physiology and pathology into the practice of obstetrics. For Czechoslovaks the political democracy coming out of America through Masaryk was attractive, but of particular interest was native and personal democracy of Americans as a way of life. John

  10. Maniac Talk - Alexander Kashlinsky

    NASA Image and Video Library

    2016-09-30

    Alexander Kashlinsky Maniac Lecture, September 30, 2016 Dr. Alexander "Sasha" Kashlinsky, an astronomer/cosmologist working at NASA Goddard presented a Maniac lecture entitled, "HOW I PLANNED TO TRAVEL TO SPACE AND GOT TO STUDY IT INSTEAD: a personal journey through 6 different countries in a changing world." Sasha was born in the former Soviet Union, just as the space era got underway with the Sputnick launch. He traced his journey back to those days of Sputnick, and walked the audience through different stages of his life and career, including his interactions with Lord Martin Rees, one of the world's most eminent astronomer and John Mather, a Nobel Prize in Physics winner.

  11. Lord Byron's physician: John William Polidori on somnambulism.

    PubMed

    Finger, Stanley; Stiles, Anne

    2013-01-01

    John William Polidori (1795-1821) was the Edinburgh-trained physician hired by Lord Byron to accompany him to Switzerland, where he participated in the story-telling event proposed by Byron that led, with Polidori's help, to Mary Shelley's Frankenstein. Although those interested in English literature might also remember Polidori as the author of The Vampyre, one of the first extended works of fiction about vampires, his earlier interest in somnambulism and trance states is only beginning to be appreciated. Even more than students of Romantic literature, historians of science and medicine seem little aware of what Polidori had written about oneirodynia, a synonym for somnambulism, and how his thoughts from 1815 about such activities reflected the changing medical zeitgeist at this time. This chapter examines Polidori's medical thesis in a neuroscience context and compares what he wrote to the writings of several other physicians who were fascinated by nocturnal wanderings, their causes, their manifestations, and their possible treatments. © 2013 Elsevier B.V. All rights reserved.

  12. STS-79 Commander William Readdy in White Room

    NASA Technical Reports Server (NTRS)

    1996-01-01

    STS-79 Commander William F. Readdy gets ready to climb into the flight deck of the Space Shuttle Atlantis at Launch Pad 39A. Assisting him are white room closeout crew members Travis Thompson (from left), Jean Alexander and Jim Davis.

  13. William Hunter and lymphatics.

    PubMed

    McDonald, Stuart W; Russell, David

    2018-04-03

    William Hunter along with his brother, John, and their colleagues William Hewson, William Cruikshank and John Sheldon made a large contribution to understanding of lymphatic vessels. Hewson, Cruikshank and Sheldon all carried out mercury injections and made much progress in mapping the distribution of lymphatics in the human body. William Hunter appreciated that lymphatics absorbed fluid from the tissues of the body and that lacteals of the intestine and lymphatics are similar structures. John Hunter carried out an elegant series of experiments that proved that lacteals absorb products of digestion. The Hunters, however, were wrong in dismissing absorption by blood vessels and missed the importance of blood capillaries. William Hewson showed that lymphatics were not confined to mammals but that they are present in reptiles, birds and fish. Hewson also demonstrated that tracheobronchial glands are lymph nodes and not mucus-secreting glands as previously thought. Although William Hunter appreciated that tuberculosis and venereal diseases might involve the regional lymph nodes, he does not seem to have fully grasped that malignant disease might involve the local nodes or the concept that knowledge of lymph drainage could be used to define the likely site of a primary malignancy. Copyright © 2018. Published by Elsevier GmbH.

  14. An Account of ... William Cullen: John Thomson and the Making of a Medical Biography.

    PubMed

    Shuttleton, David E

    2014-01-01

    John Thomson's An Account of the Life, Lectures and Writings of William Cullen (1832; 1859) remains a primary source for the career of the most influential academic physician in eighteenth-century Scotland and is also a significant work of medical history. But this multi-authored text, begun around 1810 by the academic surgeon, John Thomson, but only completed in 1859 by Dr David Craigie, has its own complex history. This chapter addresses what this history can reveal about the development of medical biography as a literary genre. It argues that the Account is a hybrid work shaped by a complex array of practical, domestic, intellectual, and professional pressures, as Thomson, in seeking to bolster his own career, was caught between the demands of Cullen's children for a traditional "Life" and his own more theoretical and socio-cultural interests.

  15. Alexander William Bickerton: New Zealand’s First Astrophysicist?

    NASA Astrophysics Data System (ADS)

    Gilmore, Gerard F.

    Alexander Bickerton (1842-1929) is of interest to the student of New Zealand astronomical history in several ways. He was the first Professor at Canterbury University College, and had a significant effect on the early development of the University; he was a prominent and successful teacher, Ernest Rutherford being his most famous student; he was a social activist in Victorian Christchurch, eventually establishing a small commune; and he was the originator of the stellar collision theory of novae and other astronomical phenomena. This chapter, which is a slightly revised version of Gilmore (Southern Stars, 29, 87-108, 1982), provides a summary of Bickerton's life and theories, and a bibliography for further reading.

  16. STS-79 MISSION SPECIALIST JOHN E. BLAHA AND COMMANDER WILLIAM F. READDY CHAT DURING EMERGENCY EGRESS

    NASA Technical Reports Server (NTRS)

    1996-01-01

    STS-79 Mission Specialist John E. Blaha (left) and Mission Commander William F. Readdy chat during emergency egress training at the 195-foot (59-meter) level of Launch Pad 39A. The training is part of their Terminal Countdown Demonstration Test (TCDT) activities. A dress rehearsal for launch, the TCDT culminates with a simulated countdown. The Space Shuttle Atlantis is undergoing preparations for liftoff on STS-79 no earlier than Sept. 12.

  17. William Brennan and the Failed "Theory" of Actual Malice.

    ERIC Educational Resources Information Center

    Gillmor, Donald M.

    This paper contains an analysis of Justice William Brennan's Supreme Court opinions concerning cases on freedom of expression and his interpretations of Alexander Meiklejohn's theory of actual malice in cases of libel. Particular attention is paid to Brennan's landmark contribution to the law of libel, his opinion in "New York Times v.…

  18. Rival Readings of Hegel at the "fin de siècle": The Case of William Torrey Harris and John Dewey

    ERIC Educational Resources Information Center

    Johnston, James Scott

    2013-01-01

    William Torrey Harris and John Dewey were the two most important philosophers of education in America at the "fin de siècle." This paper discusses their rival idealisms through an examination of their philosophical and educational pronouncements. As I will show, both are indebted to, and align themselves with, Hegel. However, each…

  19. Genealogy of John and Charles Bell: their relationship with the children of Charles Shaw of Ayr.

    PubMed

    Kaufman, M

    2005-11-01

    The Reverend William Bell had six children who survived infancy. Two of his sons entered the legal profession and two other sons became distinguished anatomists and surgeons--John Bell, said for 20 years to have been the leading operating surgeon in Britain and throughout the world--and Sir Charles Bell, possibly the most distinguished anatomist and physiologist of his day. Information is not known about the fifth son or their sister. Charles Shaw, a lawyer of Ayr, had four sons and two daughters who survived infancy. Two of his sons, John and Alexander, became anatomists and later surgeons at the Middlesex Hospital, and both worked closely with Charles Bell at the Great Windmill Street School of Anatomy. His third son entered the law and his fourth son became a distinguished soldier. The two daughters of Charles Shaw married into the Bell family: Barbara married George Joseph Bell and Marion married Mr (later Sir) Charles Bell.

  20. Energy and Process Optimization Assessment, Fort Stewart, GA

    DTIC Science & Technology

    2006-04-01

    ER D C/ CE R L TR -0 6 -8 Energy and Process Optimization Assessment Fort Stewart, GA John L. Vavrin, Alexander M. Zhivov, William T...distribution is unlimited. ERDC/CERL TR-06-8 April 2006 Energy and Process Optimization Assessment Fort Stewart, GA John L. Vavrin, Alexander...U.S. Army Corps of Engineers Washington, DC 20314-1000 Under Work Unit 33143 ERDC/CERL TR-06-8 ii Abstract: An Energy and Process Optimization

  1. New Models at Lasell: Q&A with President Michael Alexander

    ERIC Educational Resources Information Center

    Harney, John O.

    2018-01-01

    The "New England Journal of Higher Education" ("NEJHE") Executive Editor John O. Harney had the chance to catch up with Lasell College President Michael Alexander about the small Newton, Massachusetts, college's plans to challenge the higher education business model. The interview is presented in this article.

  2. Alexander Disease

    MedlinePlus

    ... there are no ethnic, racial, geographic, or cultural/economic differences in its distribution. Alexander disease is a ... there are no ethnic, racial, geographic, or cultural/economic differences in its distribution. Alexander disease is a ...

  3. The John Kay Williams Gold Medal of the Royal College of Surgeons of England and Glasgow 2015.

    PubMed

    Ahmed, Farooq

    2017-03-01

    This paper describes the clinical treatment of two cases presented by the recipient of the 2015 Bi-collegiate Membership in Orthodontics John Kay Williams Gold Medal of the Royal College of Surgeons of England and Glasgow. The first case describes the management of an 11-year-old male with a class II Division 1 malocclusion with a 9 mm overjet complicated by an upper anterior odontome and moderate upper arch crowding. The second case describes a 14-year-old female with a class III malocclusion with a reverse overjet complicated by moderate lower arch crowding and previously removed upper permanent canines.

  4. William Healy, M.D., Father of the American Child Guidance Movement

    DTIC Science & Technology

    1981-08-01

    courts, was another important development, starting in 1899. Meyer, Sigmund Freud , and Healy all contributed to the next step, which coupled the...Dummer Papers lists 454 correspondents. The prominent psychiatrists include: Franz Alexander, Trigant Burrow, Havelock Ellis, Flanders Dunbar, Sigmund ... Freud , Roy Grinker, William Healy, Karen Homey, Marion E. Kenworthy, Lawson Lowrey, Julse Masserman, Karl Menninger, Adolf Meyer, Smith Ely Jelliffe

  5. The John Kay Williams Gold Medal of the Royal College of Surgeons of England and Glasgow 2013.

    PubMed

    Clayton, Christopher Jonathan

    2015-06-01

    This paper describes the clinical treatment of two cases treated by the recipient of the 2013 Membership in Orthodontics John Kay Williams Gold Medal of the Royal College of Surgeons of England and Glasgow. The first case describes the management of a 12-year-old male with a class II division 1 malocclusion complicated by Molar Incisal Hypominaralization, an increased overjet and severe upper arch crowding using fixed appliances with anchorage support from temporary anchorage devices. The second case involves the management of a class II division 2 malocclusion complicated by crowding of the upper and lower arches treated on an extraction basis using fixed appliances.

  6. Alexander Archipelago, Southeastern Alaska

    NASA Technical Reports Server (NTRS)

    2002-01-01

    West of British Columbia, Canada, and south of the Yukon Territory, the southeastern coastline of Alaska trails off into the islands of the Alexander Archipelago. The area is rugged and contains many long, U-shaped, glaciated valleys, many of which terminate at tidewater. The Alexander Archipelago is home to Glacier Bay National Park. The large bay that has two forks on its northern end is Glacier Bay itself. The eastern fork is Muir inlet, into which runs the Muir glacier, named for the famous Scottish-born naturalist John Muir. Glacier Bay opens up into the Icy Strait. The large, solid white area to the west is Brady Icefield, which terminates at the southern end in Brady's Glacier. To locate more interesting features from Glacier Bay National Park, take a look at the park service map. As recently as two hundred years ago, a massive ice field extended into Icy Strait and filled the Glacier Bay. Since that time, the area has experienced rapid deglaciation, with many large glaciers retreating 40, 60, even 80 km. While temperatures have increased in the region, it is still unclear whether the rapid recession is part of the natural cycle of tidewater glaciers or is an indicator of longer-term climate change. For more on Glacier Bay and climate change, read an online paper by Dr. Dorothy Hall, a MODIS Associate Science Team Member. Credit: Jacques Descloitres, MODIS Land Rapid Response Team, NASA/GSFC

  7. [Alcohol consumption as portrayed in William Hogarth's prints Beer Street and Gin Lane and in the works of John Wesley: similarities and differences].

    PubMed

    Renders, Helmut

    2012-12-01

    The article compares William Hogarth's Gin Lane and Beer Street with texts by his contemporary John Wesley, spiritus rector of the Methodist movement. Although Hogarth had portrayed the Methodist religious movement in some of his prints as dangerously enthusiastic, both men defended a similar agenda concerning alcohol consumption. The similarities in their two ways of understanding the issue can be explained by culturally established customs, while distinct social outlooks can account for their differences.

  8. Activities commemorating John B. Herrington as first Native American astronaut

    NASA Technical Reports Server (NTRS)

    2002-01-01

    KENNEDY SPACE CENTER, FLA. -- Chickasaw Nation Cultural Resources Director Haskell Alexander (left) presents a gift to Joyce and James Herrington, parents of John Herrington, mission specialist on mission STS-113. Herrington is the first Native American to be going into space.

  9. Alexander the Great's relationship with alcohol.

    PubMed

    Liappas, J A; Lascaratos, J; Fafouti, S; Christodoulou, G N

    2003-05-01

    This study sought to clarify if Alexander the Great indulged pathologically in alcohol and whether it contributed to his death. The texts of the historians Diodorus of Sicily, Plutarch, Arrian, Curtius Rufus, Athenaeus, Aelian and Justin were studied, with their information concerning wine consumption by Macedonians, and especially Alexander, and were evaluated. The surviving historical texts, all later than Alexander's epoch, are based on a series of contemporary histories and especially on the 'Royal Journals', an official diary written in the imperial court. Alexander consumed large quantities of undiluted wine periodically, reaching pathological intoxication. However, the existing data do not provide convincing evidence that Alexander the Great manifested abuse of or dependence on alcohol according to DSM-IV or ICD-10 criteria and it seems unlikely that alcohol was involved in his untimely death.

  10. Genetics Home Reference: Alexander disease

    MedlinePlus

    ... the prognosis of a genetic condition? Genetic and Rare Diseases Information Center Frequency The prevalence of Alexander disease ... Degenerative Nerve Diseases Health Topic: Leukodystrophies Genetic and Rare Diseases Information Center (1 link) Alexander disease Additional NIH ...

  11. Dimensions of Educational Need.

    ERIC Educational Resources Information Center

    Johns, Roe L., Ed.; And Others

    Roe L. Johns and J. Alan Thomas survey the problem of educational need; and Kern Alexander considers the implications of the dimensions of educational need for school financing. Dimensions of need in the following areas are defined: early childhood and basic elementary and secondary education, by William P. McLure; educational programs for…

  12. Osler usque ad mare: the SS William Osler

    PubMed Central

    Bryan, C S; Fransiszyn, M

    1999-01-01

    William Osler's connections with the sea included a strong family history of seafaring, his own transatlantic crossings (of which there were at least 32) and the occasional use of nautical imagery in his inspirational writings. An unusual Oslerian connection with the sea emerged after his death in the form of a World War II Liberty ship. Through the SS William Osler and its sister ships, Osler was symbolically reunited with colleagues associated with the early days of the Johns Hopkins Hospital. The William Osler circumnavigated the globe in 1943 without engaging the enemy. She was then converted into an army hospital ship and renamed the USHS Wisteria. PMID:10530306

  13. John Glenn during preflight training for STS-95

    NASA Image and Video Library

    1998-04-14

    S98-06936 (28 April 1998) --- U.S. Sen. John H. Glenn Jr. (D.-Ohio), is assisted by suit experts Jean Alexander and Carlous Gillis prior to a training session at the Johnson Space Center (JSC). The STS-95 crew members are getting prepared for a scheduled Oct. 29 launch aboard the Space Shuttle Discovery. The photo was taken by Joe McNally, National Geographic, for NASA.

  14. Harvey Cushing at Johns Hopkins.

    PubMed

    Long, D M

    1999-11-01

    Harvey Cushing began surgical training with William Halsted at Johns Hopkins in 1896. Cushing joined the Johns Hopkins faculty in 1900 and spent 1 year in Europe in the laboratory of Theodore Kocher. He returned to Johns Hopkins, where he founded neurosurgery as an independent specialty, established the concept of the clinician scientist, discovered the hormonal properties of the pituitary gland and founded endocrinology, introduced intraoperative x-rays into surgical practice, introduced blood pressure monitoring into the operating room, and wrote the first definitive text on neurosurgery. Although there have been many pioneers in our field, Cushing, more than anyone else, developed neurosurgery as a specialty and left a legacy of talented neurosurgeons to develop and expand the field.

  15. A psychoanalytic study of Alexander the Great.

    PubMed

    Thomas, K R

    1995-12-01

    The purpose of this paper was to demonstrate how Freudian concepts such as the Oedipus complex, castration anxiety, fear of loss of love, the psychosexual stages of development, and the tripartite structure of personality can be used to understand the life and achievements of Alexander the Great. To accomplish this purpose, specific incidents, myths, and relationships in Alexander's life were analyzed from a Freudian psychoanalytic perspective. Green (1991), in his recent biography of Alexander, has questioned the merit of using Freudian concepts to understand Alexander's character. In fact, he stated specifically: If he (Alexander) had any kind of Oedipus complex it came in a poor second to the burning dynastic ambition which Olympias so sedulously fostered in him; those who insist on his psychological motivation would do better to take Adler as their mentor than Freud (p.56). Later, in the concluding section of his book, Green (1991, pp. 486-487) discounted Freudian interpretations of Alexander's distaste for sex, the rumors of his homosexual liaisons, his partiality for middle-aged or elderly ladies, and the systematic domination of his early years by Olympias as little more than the projected fears and desires of the interpreters. And again, an Adlerian power-complex paradigm was suggested as the preferable theoretical framework to use. Green's argument was based primarily on an exchange, reported originally by Plutarch, which took place between Alexander and Philip prior to Alexander's tutorship with Aristotle. Purportedly, Philip enjoined his son to study hard and pay close attention to all Aristotle said "so that you may not do a great many things of the sort that I am sorry I have done." At this point, Alexander "somewhat pertly" took Philip to task "because he was having children by other women besides his wife." Philip's reply was: "Well then, if you have many competitors for the kingdom, prove yourself honorable and good, so that you may obtain the

  16. A Yankee at Oxford: John William Draper at the British Association for the Advancement of Science at Oxford, 30 June 1860

    PubMed Central

    Ungureanu, James C.

    2016-01-01

    This paper contributes to the revisionist historiography on the legendary encounter between Samuel Wilberforce and Thomas Henry Huxley at the 1860 meeting in Oxford of the British Association for the Advancement of Science. It discusses the contents of a series of letters written by John William Draper and his family reflecting on his experience at that meeting. The letters have recently been rediscovered and have been neither published nor examined at full length. After a preliminary discussion on the historiography of the Oxford debate, the paper discloses the contents of the letters and then assesses them in the light of other contemporary accounts. The letters offer a nuanced reinterpretation of the event that supports the growing move towards a revisionist account. PMID:27386714

  17. Paleontology in parts: Richard Owen, William John Broderip, and the serialization of science in early Victorian Britain.

    PubMed

    Dawson, Gowan

    2012-12-01

    While a great deal of scholarly attention has been given to the publication of serialized novels in early Victorian Britain, there has been hardly any consideration of the no less widespread practice of issuing scientific works in parts and numbers. What scholarship there has been has insisted that scientific part-works operated on entirely different principles from the strategies for maintaining readerly interest that were being developed by serial novelists like Charles Dickens. Deploying the methods of book history, this essay examines the reporting of Richard Owen's celebrated paleontological reconstructions from the 1830s and 1840s in the serialized formats of the Proceedings of the Zoological Society, his own History of British Fossil Mammals, and, in particular, the Penny Cyclopaedia. It argues that Owen, along with his close friend William John Broderip, clearly recognized the affective possibilities of the serial format and that they exploited the Penny Cyclopaedia's sequential mode of publication to evoke suspense and expectation in their anonymous but collaboratively authored accounts of Owen's paleontological researches.

  18. John Whitridge Williams, MD (1866–1931) of Baltimore: pioneer of academic obstetrics

    PubMed Central

    Dunn, P M

    2007-01-01

    Williams was the founder of academic obstetrics in the United States and with his textbook was the recognised leader of this discipline in America during the first 30 years of the 20th century. PMID:17185435

  19. John Alexander Sinton, MD FRS VC (1884-1956).

    PubMed

    Cook, G C

    2016-05-01

    Brigadier John Sinton is the only individual in history to have been both awarded the Victoria Cross and also elected to the Royal Society. He qualified at Belfast and afterwards joined the Indian Medical Service (IMS). Serving before and during the Great War (1914-18), he was first posted to the North-West Frontier province, and afterwards as a captain in the Indian Expeditionary force in Mesopotamia (now Iraq). It was there in 1916 that, shot in both arms during an engagement and under heavy gunfire, he remained steadfastly at his post; for this bravery he received the Victoria Cross. Following the war he carried out major researches into malaria in India, and became Director of the Malaria Survey of India Both there and shortly afterwards, Sinton published about 200 papers on various aspects of malaria and leishmaniasis. In England, he later worked at the London School of Hygiene and Tropical Medicine and the Ministry of Health's laboratory at Horton, Epsom. In 1946, he was elected to the Royal Society for his researches into malaria and kala-azar, and following retirement he underwent another distinguished career in Northern Ireland. © The Author(s) 2014.

  20. 27 CFR 9.53 - Alexander Valley.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2013-04-01 2013-04-01 false Alexander Valley. 9.53 Section 9.53 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY ALCOHOL AMERICAN VITICULTURAL AREAS Approved American Viticultural Areas § 9.53 Alexander Valley. (a) Name. The name of the...

  1. 27 CFR 9.53 - Alexander Valley.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2012-04-01 2012-04-01 false Alexander Valley. 9.53 Section 9.53 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS AMERICAN VITICULTURAL AREAS Approved American Viticultural Areas § 9.53 Alexander Valley. (a) Name. The name of the...

  2. 27 CFR 9.53 - Alexander Valley.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Alexander Valley. 9.53 Section 9.53 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS AMERICAN VITICULTURAL AREAS Approved American Viticultural Areas § 9.53 Alexander Valley. (a) Name. The name of the...

  3. 27 CFR 9.53 - Alexander Valley.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2011-04-01 2011-04-01 false Alexander Valley. 9.53 Section 9.53 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS AMERICAN VITICULTURAL AREAS Approved American Viticultural Areas § 9.53 Alexander Valley. (a) Name. The name of the...

  4. 27 CFR 9.53 - Alexander Valley.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2014-04-01 2014-04-01 false Alexander Valley. 9.53 Section 9.53 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY ALCOHOL AMERICAN VITICULTURAL AREAS Approved American Viticultural Areas § 9.53 Alexander Valley. (a) Name. The name of the...

  5. The Authority of Truth: Religion and the John Peter Zenger Case.

    ERIC Educational Resources Information Center

    Nord, David Paul

    An appreciation of the religious milieu of the John Peter Zenger libel case of 1735 can help explain the nature of the Zenger defense as prepared by Alexander Hamilton, the meaning of the jury's verdict, and the ambiguous legacy of the trial for freedom of expression in the United States. In essence, the case was a disputation on "truth"…

  6. Activities commemorating John B. Herrington as first Native American astronaut

    NASA Technical Reports Server (NTRS)

    2002-01-01

    KENNEDY SPACE CENTER, FLA. - Chickasaw Indian princesses 'sign' the Lord's Prayer during a Native American Ceremony at the Rocket Garden in the KSC Visitor Complex. The princesses are Crystal Underwood, Julie Underwood and Tamela Alexander. The ceremony was part of several days' activities commemorating John B. Herrington as the first tribally enrolled Native American astronaut to fly on a Shuttle mission. Herrington is a Mission Specialist on STS-113.

  7. "Most brilliant in judgment": Alexander the Great and Aristotle.

    PubMed

    Lainas, Panagiotis; Panutsopulos, Dimitrios; Skandalakis, Panagiotis N; Zoras, Odysseas; Skandalakis, John E

    2005-03-01

    From historical sources, it is evident that Alexander the Great was indebted to one of his teachers, Aristotle of Stagira. It was the teaching of Aristotle that evoked all the nascent talents of young Alexander and turned him into a great man. Alexander was extremely interested in the secrets of medicine and considered it an art. The medical knowledge he acquired from Aristotle may have saved his life and the lives of his troops on many occasions. If Alexander did not possess medical knowledge and if his everyday life had not been so greatly influenced by medicine, he might never have been able to create his empire.

  8. Astronaut John Glenn - Crew Quarters - Prelaunch - Cape

    NASA Image and Video Library

    1962-02-20

    S62-00377 (20 Feb. 1962) --- Astronaut John H. Glenn Jr., walking out of building with Dr. William K. Douglas (to Glenn's left), and Joe W. Schmitt, NASA's suit technician (in front of Dr. Douglas). This Mercury Atlas 6 (MA-6) ?Friendship 7? flight marks America's first manned Earth-orbiting spaceflight. Photo credit: NASA

  9. John A. Simpson (1916-2000)

    NASA Astrophysics Data System (ADS)

    Jokipii, J. R.; Gloeckler, G.

    John Alexander Simpson, a long-time member and Fellow of AGU, member of the National Academy of Sciences, and last year's recipient of the Bowie Medal, died on August 31, 2000, from complications following open heart surgery. He was 83 years old and a professor emeritus at the University of Chicago, where he spent most of an extraordinarily varied and productive career.He received his bachelor's degree from Reed College in 1940, and a master's and a doctorate from New York University in 1942 and 1943. After working on the Manhattan Project until 1946, he joined the University of Chicago faculty where he rose through the ranks and was appointed to a succession of prestigious named professorships.

  10. Astronaut John Glenn leaving crew quarters prior to launch

    NASA Image and Video Library

    1961-02-20

    S62-00330 (1962) --- Astronaut John H. Glenn Jr. (left), Dr. William Douglas, astronauts flight surgeon, and equipment specialist Joe Schmitt leave crew quarters prior to Mercury-Atlas 6 (MA-6) mission. Glenn is in his pressure suit and is carrying the portable ventilation unit. Photo credit: NASA

  11. Alexander the Great and West Nile virus encephalitis.

    PubMed

    Marr, John S; Calisher, Charles H

    2003-12-01

    Alexander the Great died in Babylon in 323 BC. His death at age 32 followed a 2-week febrile illness. Speculated causes of death have included poisoning; assassination, and a number of infectious diseases. One incident, mentioned by Plutarch but not considered by previous investigators, may shed light on the cause of Alexander's death. The incident, which occurred as he entered Babylon, involved a flock of ravens exhibiting unusual behavior and subsequently dying at his feet. The inexplicable behavior of ravens is reminiscent of avian illness and death weeks before the first human cases of West Nile virus infection were identified in the United States. We posit that Alexander may have died of West Nile virus encephalitis.

  12. The Rev. John Bracken v. the Visitors of William and Mary College: A Post-Revolutionary Problem in Visitatorial Jurisdiction.

    ERIC Educational Resources Information Center

    Bridge, J. W.

    1979-01-01

    Reforms in 1779 at the College of William and Mary caused a professor to be dismissed, after which he took legal action against the institution. It is concluded that English corporate law was abused in defending against the professor's action. (Journal availability: College of William and Mary, Williamsburg, VA 23185, $3.00.) (MSE)

  13. A complex-network perspective on Alexander's wholeness

    NASA Astrophysics Data System (ADS)

    Jiang, Bin

    2016-12-01

    The wholeness, conceived and developed by Christopher Alexander, is what exists to some degree or other in space and matter, and can be described by precise mathematical language. However, it remains somehow mysterious and elusive, and therefore hard to grasp. This paper develops a complex network perspective on the wholeness to better understand the nature of order or beauty for sustainable design. I bring together a set of complexity-science subjects such as complex networks, fractal geometry, and in particular underlying scaling hierarchy derived by head/tail breaks - a classification scheme and a visualization tool for data with a heavy-tailed distribution, in order to make Alexander's profound thoughts more accessible to design practitioners and complexity-science researchers. Through several case studies (some of which Alexander studied), I demonstrate that the complex-network perspective helps reduce the mystery of wholeness and brings new insights to Alexander's thoughts on the concept of wholeness or objective beauty that exists in fine and deep structure. The complex-network perspective enables us to see things in their wholeness, and to better understand how the kind of structural beauty emerges from local actions guided by the 15 fundamental properties, and in particular by differentiation and adaptation processes. The wholeness goes beyond current complex network theory towards design or creation of living structures.

  14. Dr Elizabeth Alexander: First Female Radio Astronomer

    NASA Astrophysics Data System (ADS)

    Orchiston, Wayne

    2005-01-01

    During March-April 1945, solar radio emission was detected at 200 MHz by operators of a Royal New Zealand Air Force radar unit located on Norfolk Island. Initially dubbed the `Norfolk Island Effect', this anomalous radiation was investigated throughout 1945 by British-born Elizabeth Alexander, head of the Operational Research Section of the Radio Development Laboratory in New Zealand. Alexander prepared a number of reports on this work, and in early 1946 she published a short paper in the newly-launched journal, Radio & Electronics. A geologist by training, Elizabeth Alexander happened to be in the right place at the right time, and unwittingly became the first woman in the world to work in the field that would later become known as radio astronomy. Her research also led to further solar radio astronomy projects in New Zealand in the immediate post-war year, and in part was responsible for the launch of the radio astronomy program at the Division of Radiophysics, CSIRO, in Sydney.

  15. "Who Killed William Robinson?" Exploring a Nineteenth-Century Murder Online

    ERIC Educational Resources Information Center

    Sandwell, Ruth

    2004-01-01

    In 1996, the author and fellow-historian John Lutz set about creating a teaching tool for history that would acquaint students with primary documents and take full advantage of the brand-new technology of the World Wide Web. He launched the website, entitled "Who Killed William Robinson? Race, Justice and Settling the Land,"…

  16. John Bardeen: an extraordinary physicist

    NASA Astrophysics Data System (ADS)

    Hoddeson, Lillian

    2008-04-01

    On the morning of 1 November 1956 the US physicist John Bardeen dropped the frying-pan of eggs that he was cooking for breakfast, scattering its contents on the kitchen floor. He had just heard that he had won the Nobel Prize for Physics along with William Shockley and Walter Brattain for their invention of the transistor. That evening Bardeen was startled again, this time by a parade of his colleagues from the University of Illinois marching to the door of his home bearing champagne and singing "For He's a Jolly Good Fellow".

  17. Williams syndrome

    MedlinePlus

    ... with Williams syndrome may show: A flattened nasal bridge with small upturned nose Long ridges in the ... Alternative Names Williams-Beuren syndrome Images Low nasal bridge Chromosomes and DNA References Morris CA. Williams syndrome. ...

  18. Alexander's (356-323 BC) expeditionary Medical Corps 334-323 BC.

    PubMed

    Retsas, Spyros

    2009-08-01

    Alexander had a profound interest in medicine and healing. Original Greek texts survive mainly from the works of Plutarch and Arrian. This paper examines original sources naming the physicians who participated in Alexander's expedition in Asia, the battle injuries he sustained and his final illness in Babylon.

  19. The Brief Military Career of Dr. William H. Welch.

    PubMed

    Gilman, James K

    2017-03-01

    The purpose of this article is to examine the Army service of Dr. William H. Welch during World War I. Archival research utilizing prime source documents in the William H. Welch Collection of the Alan M. Chesney Medical Archives for the Johns Hopkins Medical Institutions. Welch joined the Army at the age of 67 after serving as one of the principal transformational forces for reforming medical education in the United States and founding the first academic institution for educating public health professionals in the United States, the Johns Hopkins School of Public Health and Hygiene. His longstanding relationship with Army Surgeon General William Gorgas served as the backdrop for Welch's service. Welch served as both a staff officer and as a traveling medical inspector general, assessing the medical care of troops preparing for overseas duty. He did not adapt particularly well to military dress and decorum but his status as one of the icons of American medicine rendered these shortcomings insignificant. Welch was joined in Army service by a number of American medical luminaries-both Mayo brothers, George Crile, and Harvey Cushing among them. Although Welch remained on active duty for only 13 months, he maintained a nominal relationship with Army medicine through appointment to the Medical Officer Reserve Corps until the time of his death. 2016 marks the centennial of the establishment of the first independent academic institution in America dedicated to education and training of professionals focused on public health and hygiene issues. 2017 marks the centennial of U.S. entry into World War I. Dr. William H. Welch played an important role in both of these historic events and, although his active service was brief, the impact of his example was substantial. Analysis of his military career in its full historical context provides insight into the relationship between academic medicine and military medicine during periods of armed conflict. Reprint & Copyright © 2017

  20. 12. Detail view of southeast side window of AlexanderAlmon House ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. Detail view of southeast side window of Alexander-Almon House with rain barrel at lower left and roof rafter tails at top, facing northwest. - Alexander-Almon House, 130 Philip Almon Road, Roopville, Carroll County, GA

  1. "I Had Made a Mistake": William H. Kilpatrick and the Project Method

    ERIC Educational Resources Information Center

    Knoll, Michael

    2012-01-01

    Background/Context: William H. Kilpatrick is known worldwide as "Mr. Project Method." Despite considerable scholarship by Lawrence A. Cremin, Herbert M. Kliebard, Milton A. Bleeke, John A. Beineke, and others, the origin of Kilpatrick's celebrated paper of 1918 has never been explored in depth and its historical context. Focus of Study:…

  2. 33 CFR 162.250 - Port Alexander, Alaska; speed of vessels.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Port Alexander, Alaska; speed of... Alexander, Alaska; speed of vessels. (a) Definition. The term “Port Alexander” includes the entire inlet from its head to its entrance from Chatham Strait. (b) Speed. The speed of all vessels of 5 tons or...

  3. 33 CFR 162.250 - Port Alexander, Alaska; speed of vessels.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Port Alexander, Alaska; speed of... Alexander, Alaska; speed of vessels. (a) Definition. The term “Port Alexander” includes the entire inlet from its head to its entrance from Chatham Strait. (b) Speed. The speed of all vessels of 5 tons or...

  4. The Scientific Work of John A. McClelland: A Recently Discovered Manuscript

    NASA Astrophysics Data System (ADS)

    O'Connor, Thomas

    2010-09-01

    John Alexander McClelland (1870-1920) was educated at Queen’s College Galway and the Cavendish Laboratory in Cambridge. He was Professor of Experimental Physics at University College Dublin from 1900 to 1920. He was best known for his pioneering work on the scattering of β rays and on the conductivity of gases and the mobility of ions. He established a research school on atmospheric aerosols that was continued by his successor, John James Nolan (1887-1952), which strongly influenced physics research in Ireland up to the present. A recently discovered manuscript of a commemorative address by Nolan in 1920, which is reproduced in Appendix I, is a unique contemporary summary of McClelland’s research and character, and is an important contribution to the history of experimental physics in Ireland.

  5. The efficacy of medicine during the campaigns of Alexander the Great.

    PubMed

    Ruffin, J R

    1992-09-01

    This paper examines the various factors that may have determined the efficacy of physicians during the campaigns of Alexander the Great. Such general variables as the adequacy of preparation, the nature of the medical profession, and the extent of preventative measures are all discussed at the outset of the paper, followed by a more detailed examination of the specific wounds, illnesses, and treatments of Alexander as described in the accounts of the Alexander historians Plutarch, Curtius, and Arrian. Where no remedy is given by these writers (as is usually the case), this paper speculates on the efficacy of possible treatments as advocated in the contemporary Hippocratic corpus. Casualty statistics of the campaigns are compared to a similar review of Homer's Iliad. From these examinations, this paper concludes that wound treatment efficacy was significantly greater than that of illness treatment, and that Alexander lost many more men to disease than to the wounds of war.

  6. William Herschel's 'Hole in the Sky' and the discovery of dark nebulae

    NASA Astrophysics Data System (ADS)

    Steinicke, Wolfgang

    2016-12-01

    In 1785 William Herschel published a paper in the Philosophical Transactions containing the remarkable section "An opening or hole". It describes an unusual vacant place in Scorpius. This matter falls into oblivion until Caroline Herschel initiated a correspondence with her nephew John in 1833. It contains Herschel's spectacular words "Hier ist wahrhaftig ein Loch im Himmel" ("Here truly is a hole in the sky"). About a hundred years later, Johann Georg Hagen, Director of the Vatican Observatory, presented a spectacular candidate for the 'hole', discovered in 1857 by Angelo Secchi in Sagittarius and later catalogued by Edward E. Barnard as the dark nebula B 86. Hagen's claim initiated a debate, mainly in the Journal of the British Astronomical Association, about the identity of Herschel's 'object'. Though things could be partly cleared up, unjustified claims still remain. This is mainly due to the fact that original sources were not consulted. A comprehensive study of the curious 'hole' is presented here. It covers major parts of the epochal astronomical work of William, Caroline and John Herschel. This includes a general study of 'vacant places', found by William Herschel and others, and the speculations about their nature, eventually leading to the finding that dark nebulae are due to absorbing interstellar matter. Some of the 'vacant places' could be identified in catalogues of dark nebulae and this leads to a 'Herschel Catalogue of Dark Nebulae' - the first historic catalogue of its kind.

  7. Alexander Falconer Sr Seamen's missionary in New Zealand, son Alexander Falconer medical superintendent for mentally ill, grandson Murray Falconer neurosurgeon.

    PubMed

    Hawgood, Barbara J

    2016-08-01

    Alexander Falconer Sr (1843-1915) came from Scotland to New Zealand. A practical Christian, he set up places of relaxation for miners, sailors and soldiers; he became the Seamen's Missionary. Son, Dr Alexander Falconer (1874-1955) trained at Otago University Medical School. As medical superintendent for the mentally ill, he urged the early introduction of psychotherapy. His son, Murray Falconer (1910-1977) was the first Nuffield Dominions Clinical Fellow, training in neurosurgery in Oxford. He was the first director of the Guy's-Maudsley Neurosurgical Unit in London and was internationally known for the surgical management of temporal lobe epilepsy in adults and children. © The Author(s) 2016.

  8. Sir John Struthers (1823-1899), Professor of Anatomy in the University of Aberdeen (1863-1889), President of the Royal College of Surgeons of Edinburgh (1895-1897).

    PubMed

    Kaufman, M H

    2015-11-01

    Between 1841 and 1845 John Struthers attended both the University of Edinburgh and some of the various Extra-mural Schools of Medicine associated with Surgeons' Hall. While a medical student he became a Member of the Hunterian Medical Society of Edinburgh and later was elected one of their Annual Presidents. He graduated with the MD Edin and obtained both the LRCS Edin and the FRCS Edin diplomas in 1845. Shortly afterwards he was invited to teach Anatomy in Dr Handyside's Extra-mural School in Edinburgh. The College of Surgeons certified him to teach Anatomy in October 1847. He had two brothers, and all three read Medicine in Edinburgh. His younger brother, Alexander, died of cholera in the Crimea in 1855 while his older brother James, who had been a bachelor all his life, practised as a Consultant Physician in Leith Hospital, Edinburgh, until his death.When associated with Dr Handyside's Extra-mural School in Edinburgh, John taught Anatomy there until he was elected to the Chair of Anatomy in Aberdeen in 1863. Much of his time was spent in Aberdeen teaching Anatomy and in upgrading the administrative facilities there. He resigned from this Chair in 1889 and subsequently was elected President of Leith Hospital from 1891 to 1897. This was in succession to his older brother, James, who had died in 1891. Later, he was elected President of the Royal College of Surgeons of Edinburgh from 1895 to 1897 and acted as its Vice-President from 1897 until his death in 1899. In 1898, Queen Victoria knighted him. His youngest son, John William Struthers, was the only one of his clinically qualified sons to survive him and subsequently was elected President of the Edinburgh College of Surgeons from 1941 to 1943. © The Author(s) 2014.

  9. 78 FR 30791 - Airworthiness Directives; Alexander Schleicher GmbH & Co. Segelflugzeugbau Sailplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-23

    ... Schleicher GmbH & Co. Segelflugzeugbau Sailplanes AGENCY: Federal Aviation Administration (FAA), Department... new airworthiness directive (AD) for all Alexander Schleicher GmbH & Co. Segelflugzeugbau Models AS... proposed AD, contact Alexander Schleicher GmbH & Co Segelflugzeugbau, Stra[szlig]e 1 D-- 36163 Poppenhausen...

  10. The Haunting Influence of Alexander Graham Bell

    ERIC Educational Resources Information Center

    Mitchell, Sue H.

    1971-01-01

    The article examines the significance that Alexander Graham Bell's attitude and actions had on the social and economic conditions experienced by deaf people during his lifetime and into the present. (CD)

  11. John Bardeen: The Only Person to Win Two Nobel Prizes in Physics

    ERIC Educational Resources Information Center

    Hoddeson, L.

    2011-01-01

    John Bardeen worked on the theory of solids throughout his physics career, winning two Nobel Prizes: the first in 1956 for the invention of the transistor with Walter Brattain and William Shockley; and the second in 1972 for the development with Leon Cooper and J Robert Schrieffer of the Bardeen-Cooper-Schrieffer (BCS) theory of superconductivity.…

  12. Alexander Disease: A Novel Mutation in GFAP Leading to Epilepsia Partialis Continua.

    PubMed

    Bonthius, Daniel J; Karacay, Bahri

    2016-06-01

    Alexander disease is a genetically induced leukodystrophy, due to dominant mutations in the glial fibrillary acidic protein (GFAP ) gene, causing dysfunction of astrocytes. We have identified a novel GFAP mutation, associated with a novel phenotype for Alexander disease. A boy with global developmental delay and hypertonia was found to have a leukodystrophy. Genetic analysis revealed a heterozygous point mutation in exon 6 of the GFAP gene. The guanine-to-adenine change causes substitution of the normal glutamic acid codon (GAG) with a mutant lysine codon (AAG) at position 312 (E312 K mutation). At the age of 4 years, the child developed epilepsia partialis continua, consisting of unabating motor seizures involving the unilateral perioral muscles. Epilepsia partialis continua has not previously been reported in association with Alexander disease. Whether and how the E312 K mutation produces pathologic changes and clinical signs that are unique from other Alexander disease-inducing mutations in GFAP remain to be determined. © The Author(s) 2015.

  13. A Study of Combined Arms Warfare by Alexander the Great.

    DTIC Science & Technology

    1998-06-05

    source of Greek literature written about Alexander is from the famous biographer Plutarch . He wrote the Life of Alexander in the second century C.E...emperor Trajan, was appointed governor of Greece for a short time, and like Arrian, also served as Archon. It was in his later years that Plutarch began...and heavy troops were positioned by their territory behind the main battle line. According to Arrian and Plutarch , 41 Darius’ army at this time

  14. Alexander the Great and West Nile Virus Encephalitis

    PubMed Central

    Marr, John S.

    2003-01-01

    Alexander the Great died in Babylon in 323 BC. His death at age 32 followed a 2-week febrile illness. Speculated causes of death have included poisoning, assassination, and a number of infectious diseases. One incident, mentioned by Plutarch but not considered by previous investigators, may shed light on the cause of Alexander’s death. The incident, which occurred as he entered Babylon, involved a flock of ravens exhibiting unusual behavior and subsequently dying at his feet. The inexplicable behavior of ravens is reminiscent of avian illness and death weeks before the first human cases of West Nile virus infection were identified in the United States. We posit that Alexander may have died of West Nile encephalitis. PMID:14725285

  15. Love, Justice, and Education: John Dewey and the Utopians. Landscapes of Education

    ERIC Educational Resources Information Center

    Schubert, William H.

    2010-01-01

    Love, Justice, and Education by William H. Schubert brings to life key ideas in the work of John Dewey and their relevance for the world today. He does this by imagining continuation of a highly evocative article that Dewey published in the New York Times in 1933. Dewey wrote from the posture of having visited Utopia. Schubert begins each of…

  16. [Williams-Beuren syndrome (Williams syndrome). Case report].

    PubMed

    Miklós, Györgyi; Fekete, György; Haltrich, Irén; Tóth, Miklós; Reismann, Péter

    2017-11-01

    Williams syndrome is a rare genetic disorder, that occurs equally in all ethnic groups and both sexes. The diagnosis might be missed during childhood in mild cases. However, establishing the diagnosis is important, not only to find the cause of intellectual disability but to look for cardiovascular, endocrine, psychiatry, urology and other conditions, which can occur at any age in the patients' lifetime. This case report presents the story of 47-year-old woman, who was admitted with haematemesis. During her stay on the ward, in the light of the distinctive facial features, mental retardation, and social behaviour patterns, the possibility of Williams syndrome emerged. Later, the diagnosis was confirmed by genetic analysis. This female is the oldest living patient with Williams syndrome in Hungary. Orv Hetil. 2017; 158(47): 1883-1888.

  17. 33 CFR 167.1702 - In Prince William Sound: Prince William Sound Traffic Separation Scheme.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... William Sound Traffic Separation Scheme. 167.1702 Section 167.1702 Navigation and Navigable Waters COAST... SEPARATION SCHEMES Description of Traffic Separation Schemes and Precautionary Areas Pacific West Coast § 167.1702 In Prince William Sound: Prince William Sound Traffic Separation Scheme. The Prince William Sound...

  18. 33 CFR 167.1702 - In Prince William Sound: Prince William Sound Traffic Separation Scheme.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... William Sound Traffic Separation Scheme. 167.1702 Section 167.1702 Navigation and Navigable Waters COAST... SEPARATION SCHEMES Description of Traffic Separation Schemes and Precautionary Areas Pacific West Coast § 167.1702 In Prince William Sound: Prince William Sound Traffic Separation Scheme. The Prince William Sound...

  19. 33 CFR 167.1702 - In Prince William Sound: Prince William Sound Traffic Separation Scheme.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... William Sound Traffic Separation Scheme. 167.1702 Section 167.1702 Navigation and Navigable Waters COAST... SEPARATION SCHEMES Description of Traffic Separation Schemes and Precautionary Areas Pacific West Coast § 167.1702 In Prince William Sound: Prince William Sound Traffic Separation Scheme. The Prince William Sound...

  20. 33 CFR 167.1702 - In Prince William Sound: Prince William Sound Traffic Separation Scheme.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... William Sound Traffic Separation Scheme. 167.1702 Section 167.1702 Navigation and Navigable Waters COAST... SEPARATION SCHEMES Description of Traffic Separation Schemes and Precautionary Areas Pacific West Coast § 167.1702 In Prince William Sound: Prince William Sound Traffic Separation Scheme. The Prince William Sound...

  1. 33 CFR 167.1702 - In Prince William Sound: Prince William Sound Traffic Separation Scheme.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... William Sound Traffic Separation Scheme. 167.1702 Section 167.1702 Navigation and Navigable Waters COAST... SEPARATION SCHEMES Description of Traffic Separation Schemes and Precautionary Areas Pacific West Coast § 167.1702 In Prince William Sound: Prince William Sound Traffic Separation Scheme. The Prince William Sound...

  2. The Berlin tradition in Chicago: Franz Alexander and the Chicago Institute for Psychoanalysis.

    PubMed

    Schmidt, Erika S

    2010-01-01

    Freud considered Franz Alexander, the first graduate of the Berlin Psychoanalytic Institute and an assistant in the Berlin Polyclinic, to be "one of our strongest hopes for the future." Alexander went on to become the first director of the Chicago Institute for Psychoanalysis in 1932 and modeled some of the Chicago Institute's mission on his Berlin experiences. He was also a researcher in psychosomatic medicine, a prolific writer about psychoanalysis and prominent in psychoanalytic organizations. As he proposed modifications in psychoanalytic technique, he became a controversial figure, especially in the elaboration of his ideas about brief therapy and the corrective emotional experience. This paper puts Alexander's achievements in historical context, draws connections between the Berlin and Chicago Institutes and suggests that, despite his quarrels with traditional psychoanalysis, Alexander's legacy may be in his attitude towards psychoanalysis, characterized by a commitment to scientific study, a willingness to experiment, and a conviction about the role of psychoanalysis within the larger culture.

  3. The Remarkable Journey of Lloyd Alexander

    ERIC Educational Resources Information Center

    Tunnel, Michael O.; Jacobs, James S.

    2007-01-01

    This article features Lloyd Alexander, an author who has produced some of the most elegant and powerful prose in the history of modern children's literature. Lloyd began writing seriously in high school, and though he wrote and submitted many poems and short stories, his only success was being named a finalist in the "Writer's Digest" Short Story…

  4. Tissue and cellular rigidity and mechanosensitive signaling activation in Alexander disease.

    PubMed

    Wang, Liqun; Xia, Jing; Li, Jonathan; Hagemann, Tracy L; Jones, Jeffrey R; Fraenkel, Ernest; Weitz, David A; Zhang, Su-Chun; Messing, Albee; Feany, Mel B

    2018-05-15

    Glial cells have increasingly been implicated as active participants in the pathogenesis of neurological diseases, but critical pathways and mechanisms controlling glial function and secondary non-cell autonomous neuronal injury remain incompletely defined. Here we use models of Alexander disease, a severe brain disorder caused by gain-of-function mutations in GFAP, to demonstrate that misregulation of GFAP leads to activation of a mechanosensitive signaling cascade characterized by activation of the Hippo pathway and consequent increased expression of A-type lamin. Importantly, we use genetics to verify a functional role for dysregulated mechanotransduction signaling in promoting behavioral abnormalities and non-cell autonomous neurodegeneration. Further, we take cell biological and biophysical approaches to suggest that brain tissue stiffness is increased in Alexander disease. Our findings implicate altered mechanotransduction signaling as a key pathological cascade driving neuronal dysfunction and neurodegeneration in Alexander disease, and possibly also in other brain disorders characterized by gliosis.

  5. The Alexander Archipelago wolf: a conservation assessment.

    Treesearch

    David K. Person; Matthew Kirchhoff; Victor van Ballenberghe; George C. Iverson; Edward Grossman

    1996-01-01

    We summarized the scientific information available for the Alexander Archipelago wolf (Canis lupus ligoni) in the Tongass National Forest of southeast Alaska. Information concerning the morphology, distribution, taxonomy, genetics, and ecology of wolves are presented. Three issues for the conservation of wolves in southeast Alaska are discussed:...

  6. Holocene morphogenesis of Alexander the Great's isthmus at Tyre in Lebanon

    PubMed Central

    Marriner, Nick; Morhange, Christophe; Meulé, Samuel

    2007-01-01

    In 332 B.C., Alexander the Great constructed an ≈1,000-m-long causeway to seize the offshore island of Tyre. The logistics behind this engineering feat have long troubled archaeologists. Using the Holocene sedimentary record, we demonstrate that Alexander's engineers cleverly exploited a shallow proto-tombolo, or sublittoral sand spit, to breach the offshore city's defensive impregnability. We elucidate a three-phase geomorphological model for the spit's evolution. Settled since the Bronze Age, the area's geological record manifests a long history of natural and anthropogenic forcings. (i) Leeward of the island breakwater, the maximum flooding surface (e.g., drowning of the subaerial land surfaces by seawater) is dated ≈8000 B.P. Fine-grained sediments and brackish and marine-lagoonal faunas translate shallow, low-energy water bodies at this time. Shelter was afforded by Tyre's elongated sandstone reefs, which acted as a 6-km natural breakwater. (ii) By 6000 B.P., sea-level rise had reduced the dimensions of the island from 6 to 4 km. The leeward wave shadow generated by this island, allied with high sediment supply after 3000 B.P., culminated in a natural wave-dominated proto-tombolo within 1–2 m of mean sea level by the time of Alexander the Great (4th century B.C.). (iii) After 332 B.C., construction of Alexander's causeway entrained a complete anthropogenic metamorphosis of the Tyrian coastal system. PMID:17517668

  7. Holocene morphogenesis of Alexander the Great's isthmus at Tyre in Lebanon.

    PubMed

    Marriner, Nick; Morhange, Christophe; Meulé, Samuel

    2007-05-29

    In 332 B.C., Alexander the Great constructed an approximately 1,000-m-long causeway to seize the offshore island of Tyre. The logistics behind this engineering feat have long troubled archaeologists. Using the Holocene sedimentary record, we demonstrate that Alexander's engineers cleverly exploited a shallow proto-tombolo, or sublittoral sand spit, to breach the offshore city's defensive impregnability. We elucidate a three-phase geomorphological model for the spit's evolution. Settled since the Bronze Age, the area's geological record manifests a long history of natural and anthropogenic forcings. (i) Leeward of the island breakwater, the maximum flooding surface (e.g., drowning of the subaerial land surfaces by seawater) is dated approximately 8000 B.P. Fine-grained sediments and brackish and marine-lagoonal faunas translate shallow, low-energy water bodies at this time. Shelter was afforded by Tyre's elongated sandstone reefs, which acted as a 6-km natural breakwater. (ii) By 6000 B.P., sea-level rise had reduced the dimensions of the island from 6 to 4 km. The leeward wave shadow generated by this island, allied with high sediment supply after 3000 B.P., culminated in a natural wave-dominated proto-tombolo within 1-2 m of mean sea level by the time of Alexander the Great (4th century B.C.). (iii) After 332 B.C., construction of Alexander's causeway entrained a complete anthropogenic metamorphosis of the Tyrian coastal system.

  8. Hydrology, Water Quality, and Aquatic Communities of Selected Springs in the St. Johns River Water Management District, Florida

    USGS Publications Warehouse

    Walsh, Stephen J.; Knowles, Leel; Katz, Brian G.; Strom, Douglas G.

    2009-01-01

    Hydrologic, physicochemical, and aquatic community data were collected and compiled by the U.S. Geological Survey for selected springs within the St. Johns River Water Management District from January 2004 to October 2007. Nine springs were included in this study: Alexander, Apopka, Bugg, De Leon, Gemini, Green, Rock, Silver Glen, and Wekiwa. Urban lands increased in Alexander, Apopka, De Leon, Gemini, Green, and Wekiwa springsheds between 1973 and 2004, accompanied by a loss of forested and/or agricultural lands in most springsheds. Forested cover increased and open surface waters and wetlands decreased in the Bugg and Rock springsheds. Although rainfall did not change significantly over time in each springshed, spring discharge decreased significantly in De Leon, Fern Hammock, Rock, Silver, and Wekiwa Springs. Nitrate concentrations increased significantly with time in Apopka, Fern Hammock, Gemini Springs run, and Juniper Springs, and decreased significantly in Alexander Spring, Bugg Spring run, Rock Springs, and Wekiwa Springs. Phosphorus increased significantly with time in Juniper Springs and decreased significantly in Apopka, De Leon, Rock, Silver Glen, and Wekiwa Springs. Benthic macroinvertebrate communities ranged from relatively low diversity assemblages (Green Spring) to assemblages with high taxonomic richness, diversity, and dominance (Rock and De Leon Springs). Shannon-Wiener diversity index averages among samples pooled by spring were lowest for Apopka Spring and greatest for Rock, Bugg, and Silver Glen Springs. Mean Stream Condition Index for pooled samples per spring was lowest for De Leon and Gemini Springs and highest for Rock and Wekiwa Springs. Mean percentages of very tolerant taxa were lowest for Alexander Spring and highest for Bugg and Green Springs. Fish community richness was lowest for Green Spring, and greatest for Alexander Spring run and Silver Glen Springs. Forty five fish species representing 35 genera and 23 families were collected

  9. Kinesthetic Ventures Informed by the Work of F. M. Alexander, Stanislavski, Peirce, and Freud.

    ERIC Educational Resources Information Center

    Bouchard, Ed; Wright, Ben; Protzel, Michael, Ed.

    This book is about education harvested from self-observation. F. Matthias Alexander (1869-1955) studied the experience of self formation, working with motor habits. His method is used in performing arts training to enhance bodily and vocal expression. Like Alexander, Konstantine Stanislavski (1863-1938) and Sigmund Freud (1856-1939) studied human…

  10. Alexander the Great's Tomb at Siwa: The Astronomical Orientation

    NASA Astrophysics Data System (ADS)

    Papathanassiou, M.; Souvaltzis, Em.; Souvaltzi, L.; Moussas, X.

    A preliminary report on the possible astronomical orientation of the Tomb of Alexander the Great, recently found and excavated by the greek archaeologist Liana Souvaltzi. The tomb is a greek building of doric style. Its enormous dimensions make it the largest amongst the found macedonian tombs (much bigger than the tomb of Philip II, Alexander's father). The tomb faces generally south---west and its orientation could be related either to the constellation of Centaurus or to the star Canopus. The walls of the two long sides of the building have strickingly different widhts. Moreover each wall has three doors (opposite in pairs) of slightly different sizes. We examine the possibility the openings of the doors and their assymetries to be designed and constructed according to some astronomical (solar or stellar) orientations.

  11. James Taylor (1859-1946): favourite disciple of Hughlings Jackson and William Gowers.

    PubMed

    Eadie, M J

    2013-01-01

    In neurological circles today the name James Taylor (1859-1946) is probably remembered mainly for his role in editing the Selected Writings of John Hughlings Jackson, the most readily available source of Jackson's contributions to neurological knowledge. Taylors' own neurological achievements are largely or entirely forgotten, but in his day he was an influential figure whose career linked the great figures of the golden era of late nineteenth century British neurology to the neurology of the first half of the twentieth century. Not only was he a junior professional colleague and close friend of both John Hughlings Jackson and William Gowers, he also produced a substantial corpus of neurological writings in his own right, including a textbook of child neurology and the first English language account of subacute combined degeneration of the spinal cord.

  12. Alexander George Karczmar (1917-2017).

    PubMed

    Soreq, Hermona; Silman, Israel

    2017-12-01

    The neurochemistry community at large and the Advisory Board of The International Symposia on Cholinergic Mechanisms mourn the loss of Alexander George Karczmar, the elected Honorary President of these international symposia, who passed away peacefully in his Chicago home at the age of 100 on August 17, 2017. For many of us Alex was the essence of cholinergic signaling, and personified its versatile power to send messages between the brain and the peripheral tissues and organs, and to connect between body and soul. © 2017 International Society for Neurochemistry.

  13. 3. Historic American Buildings Survey J. Alexander, Photographer, 1971 DETAIL, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Historic American Buildings Survey J. Alexander, Photographer, 1971 DETAIL, ENTRANCE STOOP (LION FIGURE) - Joseph Beale House, 2301 Massachusetts Avenue, Northwest, Washington, District of Columbia, DC

  14. Alexander Graham Bell: Teacher of the Deaf.

    ERIC Educational Resources Information Center

    Bruce, Robert V.

    The lecture on Alexander Graham Bell by Dr. Robert V. Bruce, the author of a biography of Bell, focuses on Bell's association with the Clarke School for the Deaf in Massachusetts. Noted are Bell's employment by the school at 25 years of age and the preceding period during which Bell taught elocution at a boys' school in Scotland and used his…

  15. Alexander Meiklejohn in Search of Freedom and Dignity.

    ERIC Educational Resources Information Center

    Johnson, Tony W.

    1982-01-01

    Assesses the contributions of the philosopher/educator Alexander Meiklejohn. Discusses the influences of Jean-Jacques Rousseau, Immanuel Kant, and the U.S. Constitution on Meiklejohn's educational theories, which stressed that human freedom and dignity can be enhanced by rigorous examination of U.S. Supreme Court decisions and the meaning of…

  16. Piping Plover Habitat Loss at the Nature Conservancy's John E. Williams Preserve, Central North Dakota: an Interdisciplinary Study of Alkaline Prairie Pothole Glacial Lakes, Groundwater, Gravel Beaches and Vegetation Encroachment

    NASA Astrophysics Data System (ADS)

    Sciamanda, M.; Kellner, J. R.; Lamb, M. A.; Clotts, R.; Pastika, D. W.; Welter, D. J.; Brown, J. M.; Schuweiler, T. K.; Mohanty, R. B.; Vang, K. M.; Nichols, K. S.; Lorah, P. A.; Robinson, D. O.

    2016-12-01

    The Piping Plover (Charadrius melodus) is a threatened migratory bird that nests along shores of alkaline lakes, the Great Lakes, and the Atlantic Ocean. John Williams Preserve, in central North Dakota, houses one of the largest breeding populations in the world. Over the past eighty years, vegetation has encroached and caused variable habitat loss from lake to lake (Root and Ryan, 2004). Processes operating on different time scales affect lake, beach and vegetation changes: long-term global climate changes, decadal drought cycles, and seasonal and local weather. To determine how these processes interact to affect vegetation growth, soil salinity and habitat loss, we began a multidisciplinary field study. Sampled lake cores provide a chemical record of historical events and possible habitat changes. Water chemistry samples taken in different months inform groundwater flow patterns and core interpretation. Spatial analyses of local and regional groundwater systems informed placement of piezometers to determine groundwater flow. Aerial drone imagery builds on previous ground studies and allows for a quantitative spatial analysis of vegetation encroachment and geomorphic analyses. The three main lakes in our study show a general increase in concentration of major ions from east to west —from Pelican to Peterson to Williams—that mirrors westerly groundwater flow. Geochemical data from sediment cores, including LOI, XRD and XRF data, show that Williams is the most variable chemically, Pelican the least. Williams contains the most evaporate minerals, including thernardite and burkeite. Land use changes in the last 120 years may have changed lake chemistry: at 60 cm depth in cores, there are changes in the organic matter concentration and major ion chemistry, suggesting an increase in runoff and sediment input. Historical research points to changing agricultural practices as a possible cause of these changes. Initial ArcGIS analyses of detailed drone topographic data

  17. Alexander von Humboldt and the Origins of Landscape Archaeology.

    ERIC Educational Resources Information Center

    Mathewson, Kent

    1986-01-01

    Reviews the life, theories, and influence of Alexander von Humboldt, the early nineteenth century founder of modern geography. Maintains that Humboldt's novel approaches to the study of landscape antiquities have value for contemporary students in cultural and historical geography. (JDH)

  18. The Century-Old Wisdom of Alexander Graham Bell.

    ERIC Educational Resources Information Center

    Cornett, Orin

    1990-01-01

    This article reflects on Alexander Graham Bell's 1888 testimony before the Royal Commission of the United Kingdom on the Condition of the Deaf and Dumb, Etc. Excerpts are grouped by reference to (1) language education for the hearing impaired; (2) speechreading; (3) methods of teaching; (4) speech; and (5) sign language. (Author/PB)

  19. Journalism and the Educational Views of Alexander Meiklejohn.

    ERIC Educational Resources Information Center

    Palmer, Mack R.

    Alexander Meiklejohn, who died in 1964 at the age of 92, was a constitutional scholar whose major interest was education. Among Meiklejohn's beliefs were the following: the social good should take precedence over individual achievement; the liberal arts college is the institution best suited to carry out an affirmative reading of the First…

  20. 1. Historic American Buildings Survey J. Alexander, Photographer April 1969 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey J. Alexander, Photographer April 1969 3034 P STREET (right) AND ADJOINING ROWHOUSES, LOOKING EAST - Smith-Morton Row House, 3034 P Street Northwest, Washington, District of Columbia, DC

  1. Q & A: Alexander Varshavsky.

    PubMed

    Varshavsky, Alexander

    2003-07-01

    Alexander Varshavsky is Smits Professor of Cell Biology at the California Institute of Technology. He moved to Caltech in 1992, after 15 years at the MIT's Department of Biology. He was born and educated in Russia, and was 30 at the time of his emigration to the U.S. in 1977. In Russia, and for a while at MIT, he studied the structure and replication of chromosomes. Over the last 24 years, the work of his laboratory focused on the ubiquitin system and closely related fields. He is a member of the U.S. National Academy of Sciences, and has received the Gairdner Award, the Lasker Award, the General Motors Sloan Prize, the Wolf Prize, the Horwitz Prize, and the Wilson Medal.

  2. The Quest for Rigour in Physics--The Life and Legacy of John William Warren

    ERIC Educational Resources Information Center

    Leadstone, Stuart

    2017-01-01

    For over half a century, starting around 1960, physics education was put under the intellectual microscope of a London-based university lecturer--Dr John Warren. His scrutiny of physics textbooks and examination papers in particular led him to conduct a sustained assault on error, ambiguity and lack of rigour in the presentation of our subject.…

  3. Randomised controlled trial of Alexander technique lessons, exercise, and massage (ATEAM) for chronic and recurrent back pain: economic evaluation.

    PubMed

    Hollinghurst, Sandra; Sharp, Debbie; Ballard, Kathleen; Barnett, Jane; Beattie, Angela; Evans, Maggie; Lewith, George; Middleton, Karen; Oxford, Frances; Webley, Fran; Little, Paul

    2008-12-11

    An economic evaluation of therapeutic massage, exercise, and lessons in the Alexander technique for treating persistent back pain. Cost consequences study and cost effectiveness analysis at 12 month follow-up of a factorial randomised controlled trial. 579 patients with chronic or recurrent low back pain recruited from primary care. Normal care (control), massage, and six or 24 lessons in the Alexander technique. Half of each group were randomised to a prescription for exercise from a doctor plus behavioural counselling from a nurse. Costs to the NHS and to participants. Comparison of costs with Roland-Morris disability score (number of activities impaired by pain), days in pain, and quality adjusted life years (QALYs). Comparison of NHS costs with QALY gain, using incremental cost effectiveness ratios and cost effectiveness acceptability curves. Intervention costs ranged from pound30 for exercise prescription to pound596 for 24 lessons in Alexander technique plus exercise. Cost of health services ranged from pound50 for 24 lessons in Alexander technique to pound124 for exercise. Incremental cost effectiveness analysis of single therapies showed that exercise offered best value ( pound61 per point on disability score, pound9 per additional pain-free day, pound2847 per QALY gain). For two-stage therapy, six lessons in Alexander technique combined with exercise was the best value (additional pound64 per point on disability score, pound43 per additional pain-free day, pound5332 per QALY gain). An exercise prescription and six lessons in Alexander technique alone were both more than 85% likely to be cost effective at values above pound20 000 per QALY, but the Alexander technique performed better than exercise on the full range of outcomes. A combination of six lessons in Alexander technique lessons followed by exercise was the most effective and cost effective option.

  4. What is the perceived impact of Alexander technique lessons on health status, costs and pain management in the real life setting of an English hospital? The results of a mixed methods evaluation of an Alexander technique service for those with chronic back pain.

    PubMed

    McClean, Stuart; Brilleman, Sam; Wye, Lesley

    2015-07-28

    Randomised controlled trial evidence indicates that Alexander Technique is clinically and cost effective for chronic back pain. The aim of this mixed methods evaluation was to explore the role and perceived impact of Alexander Technique lessons in the naturalistic setting of an acute hospital Pain Management Clinic in England. To capture changes in health status and resource use amongst service users, 43 service users were administered three widely used questionnaires (Brief Pain Inventory, MYMOP and Client Service Resource Inventory) at three time points: baseline, six weeks and three months after baseline. We also carried out 27 telephone interviews with service users and seven face-to-face interviews with pain clinic staff and Alexander Technique teachers. Quantitative data were analysed using descriptive statistics and qualitative data were analysed thematically. Those taking Alexander Technique lessons reported small improvements in health outcomes, and condition-related costs fell. However, due to the non-randomised, uncontrolled nature of the study design, changes cannot be attributed to the Alexander Technique lessons. Service users stated that their relationship to pain and pain management had changed, especially those who were more committed to practising the techniques regularly. These changes may explain the reported reduction in pain-related service use and the corresponding lower associated costs. Alexander Technique lessons may be used as another approach to pain management. The findings suggests that Alexander Technique lessons can help improve self-efficacy for those who are sufficiently motivated, which in turn may have an impact on service utilisation levels.

  5. Non-Euclidean Space, Movement and Astronomy in Modern Art: Alexander Calder's Mobiles and Ben Nicholson's Reliefs

    NASA Astrophysics Data System (ADS)

    Malloy, Vanja

    2013-09-01

    John Keats once wrote that `there is no such thing as time and space' rather, believing that time and space are mental constructs that are subject to a variety of forms and as diverse as the human mind. In the 1920s through the 1930s, modern physics in many ways supported this idea through the various philosophical writings on the Theory of General Relativity to the masses by scientists such as Arthur Eddington and Albert Einstein. These new concepts of modern physics fundamentally changed our understanding of time and space and had substantial philosophical implications, which were absorbed by modern artists resulting in the 1936 Dimensionist Manifesto. Seeking to internalize the developments of modern science within modern art, this manifesto was widely endorsed by the most prominent figures of the avant-garde such as Marcel Duchamp, Jean Arp, Naum Gabo, Joan Miró, László Moholy-Nagy, Wassily Kandinsky and Alexander Calder. Of particular interest to this manifesto was the new concept of the fourth-dimension, which in many ways revolutionized the arts. Importantly, its interpretation varied widely in the artistic community, ranging from a purely physical four-dimensional space, to a kinetic concept of space in which space and time are linked, to a metaphysical interest in a space that exists beyond the material realm. The impact of modern science and astronomy on avant-garde art is currently a bourgeoning area of research with considerable implications to our rethinking of substantial artistic figures of this era. Through a case study of Alexander Calder's Mobiles and Ben Nicholson's Reliefs, this paper explores how these artworks were informed by an interest in modern science.

  6. Infantile Alexander Disease: Spectrum of GFAP Mutations and Genotype-Phenotype Correlation

    PubMed Central

    Rodriguez, Diana; Gauthier, Fernande; Bertini, Enrico; Bugiani, Marianna; Brenner, Michael; N'guyen, Sylvie; Goizet, Cyril; Gelot, Antoinette; Surtees, Robert; Pedespan, Jean-Michel; Hernandorena, Xavier; Troncoso, Monica; Uziel, Graziela; Messing, Albee; Ponsot, Gérard; Pham-Dinh, Danielle; Dautigny, André; Boespflug-Tanguy, Odile

    2001-01-01

    Heterozygous, de novo mutations in the glial fibrillary acidic protein (GFAP) gene have recently been reported in 12 patients affected by neuropathologically proved Alexander disease. We searched for GFAP mutations in a series of patients who had heterogeneous clinical symptoms but were candidates for Alexander disease on the basis of suggestive neuroimaging abnormalities. Missense, heterozygous, de novo GFAP mutations were found in exons 1 or 4 for 14 of the 15 patients analyzed, including patients without macrocephaly. Nine patients carried arginine mutations (four had R79H; four had R239C; and one had R239H) that have been described elsewhere, whereas the other five had one of four novel mutations, of which two affect arginine (2R88C and 1R88S) and two affect nonarginine residues (1L76F and 1N77Y). All mutations were located in the rod domain of GFAP, and there is a correlation between clinical severity and the affected amino acid. These results confirm that GFAP mutations are a reliable molecular marker for the diagnosis of infantile Alexander disease, and they also form a basis for the recommendation of GFAP analysis for prenatal diagnosis to detect potential cases of germinal mosaicism. PMID:11567214

  7. Alexander A Friedmann

    NASA Astrophysics Data System (ADS)

    Tropp, Eduard A.; Frenkel, Viktor Ya.; Chernin, Artur D.

    1993-06-01

    Our universe can be described mathematically by a simple model developed in 1922 at Petrograd (St. Petersburg) by Alexander Friedmann (1888-1925). Without the benefit of observational evidence, Friedmann predicted that the whole universe would expand and evolve with time. This astonishing prediction was confirmed seven years later by Edwin Hubble. Its originator, unfortunately didn't live to savor this triumph. This vivid biography of an outstanding scientist sets his life and work against a wide backdrop of the history of cosmological studies and its major players, such as Einstein and others. The book is a window on Friedmann's school and university years, military service, and teaching and research during a seminal period of Soviet history. The authors include unique archival material, such as Friedmann's letters from the Russian Front, as well as contemporary records and reminiscences of colleagues. There is a detailed treatment of his work in theoretical cosmology (1922-1924), set in the context of the organization of Soviet science at the time.

  8. STS-95 Payload Specialist Glenn greets baseball legend Williams following a parade in Cocoa Beach

    NASA Technical Reports Server (NTRS)

    1998-01-01

    STS-95 Payload Specialist John H. Glenn Jr. (left) greets baseball legend Ted Williams at a reception at the Double Tree Oceanfront Hotel following a parade down State Road A1A in nearby Cocoa Beach. Organizers of the parade included the Cocoa Beach Area Chamber of Commerce, the Brevard County Tourist Development Council, and the cities of Cape Canaveral and Cocoa Beach. The parade is reminiscent of those held after missions during the Mercury Program.

  9. Charles William Lacaillade. Biologist, Parasitologist, Educator, and Mentor.

    PubMed

    Imperato, Pascal James

    2017-02-01

    Charles William Lacaillade (1904-1978) was an eminent biologist in the middle decades of the twentieth century. He was born in Lawrence, Massachusetts of parents whose ancestors were French Canadians. His father, also named Charles William Lacaillade, was a dentist who graduated from Tufts University School of Dentistry in 1898. His mother, Elodia Eno, came from a family of very successful businessmen. Lacaillade was the third of six children. His two older brothers, Harold Carleton and Hector Eno, both graduated from the University of Louisville, School of Dentistry, while his younger brother, Lawrence, became a businessman. His sister, Luemma, married Dr. Henry Steadman, a veterinarian, while his youngest sister, Gloria, married a U.S. Army officer, Lieutenant Colonel Victor Anido. Lacaillade received his MS and PhD degrees in biology and zoology from Harvard University. He then became a fellow at The Rockefeller Institute for Medical Research. At both institutions, he studied under some of the most eminent biological scientists of the time. These included Rudolf W. Glaser, George Howard Parker, Theobald Smith, Carl TenBroeck, and William Morton Wheeler. At the Rockefeller Institute, he co-discovered the vector and mode of transmission of Eastern Equine Encephalomyelitis. This discovery, and the research he conducted with Rudolf W. Glaser, quickly established him as an outstanding biological researcher. However, a change in leadership at the Rockefeller Institute resulted in research priorities being given to the disciplines of general physiology, physical chemistry, and nutrition. This shift in the research agenda away from the biological sciences precluded career advancement at the Rockefeller Institute for post-doctoral fellows like Lacaillade. It was the height of the Great Depression, and even biologists with terminal doctoral degrees found it difficult to find positions. In 1935, Lacaillade accepted a position as an assistant in biology at St. John

  10. The deglacial history of NW Alexander Island, Antarctica, from surface exposure dating

    NASA Astrophysics Data System (ADS)

    Johnson, Joanne S.; Everest, Jeremy D.; Leat, Philip T.; Golledge, Nicholas R.; Rood, Dylan H.; Stuart, Finlay M.

    2012-03-01

    Recent changes along the margins of the Antarctic Peninsula, such as the collapse of the Wilkins Ice Shelf, have highlighted the effects of climatic warming on the Antarctic Peninsula Ice Sheet (APIS). However, such changes must be viewed in a long-term (millennial-scale) context if we are to understand their significance for future stability of the Antarctic ice sheets. To address this, we present nine new cosmogenic 10Be exposure ages from sites on NW Alexander Island and Rothschild Island (adjacent to the Wilkins Ice Shelf) that provide constraints on the timing of thinning of the Alexander Island ice cap since the last glacial maximum. All but one of the 10Be ages are in the range 10.2-21.7 ka, showing a general trend of progressive ice-sheet thinning since at least 22 ka until 10 ka. The data also provide a minimum estimate (490 m) for ice-cap thickness on NW Alexander Island at the last glacial maximum. Cosmogenic 3He ages from a rare occurrence of mantle xenoliths on Rothschild Island yield variable ages up to 46 ka, probably reflecting exhumation by periglacial processes.

  11. The impact of the alexander technique on improving posture and surgical ergonomics during minimally invasive surgery: pilot study.

    PubMed

    Reddy, Pramod P; Reddy, Trisha P; Roig-Francoli, Jennifer; Cone, Lois; Sivan, Bezalel; DeFoor, W Robert; Gaitonde, Krishnanath; Noh, Paul H

    2011-10-01

    One of the main ergonomic challenges during surgical procedures is surgeon posture. There have been reports of a high number of work related injuries in laparoscopic surgeons. The Alexander technique is a process of psychophysical reeducation of the body to improve postural balance and coordination, permitting movement with minimal strain and maximum ease. We evaluated the efficacy of the Alexander technique in improving posture and surgical ergonomics during minimally invasive surgery. We performed a prospective cohort study in which subjects served as their own controls. Informed consent was obtained. Before Alexander technique instruction/intervention subjects underwent assessment of postural coordination and basic laparoscopic skills. All subjects were educated about the Alexander technique and underwent post-instruction/intervention assessment of posture and laparoscopic skills. Subjective and objective data obtained before and after instruction/intervention were tabulated and analyzed for statistical significance. All 7 subjects completed the study. Subjects showed improved ergonomics and improved ability to complete FLS™ as well as subjective improvement in overall posture. The Alexander technique training program resulted in a significant improvement in posture. Improved surgical ergonomics, endurance and posture decrease surgical fatigue and the incidence of repetitive stress injuries to laparoscopic surgeons. Further studies of the influence of the Alexander technique on surgical posture, minimally invasive surgery ergonomics and open surgical techniques are warranted to explore and validate the benefits for surgeons. Copyright © 2011 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.

  12. STS-79 CREW COMMANDER WILLIAM F. READDY AT PAD 39A FOR TCDT

    NASA Technical Reports Server (NTRS)

    1996-01-01

    With the Space Shuttle Atlantis as a backdrop, STS-79 Commander William F. Readdy answers questions posed by reporters at Launch Pad 39A. Readdy and the other five members of the STS-79 crew, Pilot Terrence W. Wilcutt and Mission Specialists Jay Apt, Carl E. Walz, Tom Akers, and John E. Blaha, are at KSC for the Terminal Countdown Demonstration Test (TCDT), a dress rehearsal for the launch targeted for mid-September. STS-79 will be the fourth Shuttle-Mir docking and the first flight of the SPACEHAB Double Module.

  13. How Alexander von Humboldt's life story can inspire innovative soil research in developing countries

    NASA Astrophysics Data System (ADS)

    Bouma, Johan

    2017-09-01

    The pioneering vision of Alexander von Humboldt of science and society of the early 1800s is still highly relevant today. His open mind and urge to make many measurements characterizing the interconnected web of life are crucial ingredients as we now face the worldwide challenge of the UN Sustainable Development Goals. Case studies in the Philippines, Vietnam, Kenya, Niger, and Costa Rica demonstrate, in Alexander's spirit, interaction with stakeholders and attention to unique local conditions, applying modern measurement and modeling methods and allowing inter- and transdisciplinary research approaches. But relations between science and society are increasingly problematic, partly as a result of the information revolution and post-truth, fact-free thinking. Overly regulated and financially restricted scientific communities in so-called developed countries may stifle intellectual creativity. Researchers in developing countries are urged to leapfrog these problems in the spirit of Alexander von Humboldt as they further develop their scientific communities. Six suggestions to the science community are made with particular attention to soil science. (The Humboldt lecture, presented by the 2017 recipient of the Alexander von Humboldt lecture, Johan Bouma, can be accessed at http://client.cntv.at/egu2017/ml1.)

  14. Patients' views of receiving lessons in the Alexander technique and an exercise prescription for managing back pain in the ATEAM trial.

    PubMed

    Yardley, Lucy; Dennison, Laura; Coker, Rebecca; Webley, Frances; Middleton, Karen; Barnett, Jane; Beattie, Angela; Evans, Maggie; Smith, Peter; Little, Paul

    2010-04-01

    Lessons in the Alexander Technique and exercise prescription proved effective for managing low back pain in primary care in a clinical trial. To understand trial participants' expectations and experiences of the Alexander Technique and exercise prescription. A questionnaire assessing attitudes to the intervention, based on the Theory of Planned Behaviour, was completed at baseline and 3-month follow-up by 183 people assigned to lessons in the Alexander Technique and 176 people assigned to exercise prescription. Semi-structured interviews to assess the beliefs contributing to attitudes to the intervention were carried out at baseline with14 people assigned to the lessons in the Alexander Technique and 16 to exercise prescription, and at follow-up with 15 members of the baseline sample. Questionnaire responses indicated that attitudes to both interventions were positive at baseline but became more positive at follow-up only in those assigned to lessons in the Alexander Technique. Thematic analysis of the interviews suggested that at follow-up many patients who had learned the Alexander Technique felt they could manage back pain better. Whereas many obstacles to exercising were reported, few barriers to learning the Alexander Technique were described, since it 'made sense', could be practiced while carrying out everyday activities or relaxing, and the teachers provided personal advice and support. Using the Alexander Technique was viewed as effective by most patients. Acceptability may have been superior to exercise because of a convincing rationale and social support and a better perceived fit with the patient's particular symptoms and lifestyle.

  15. William Brickman, Master Teacher

    ERIC Educational Resources Information Center

    Swing, Elizabeth Sherman

    2010-01-01

    In this article, the author shares her encounter and relationship with William Brickman as her master teacher. William Brickman was her professor, her dissertation advisor, her mentor, and her friend. Her pursuit of a Ph.D. in late middle age may have seemed strange to friends, family, and some of her professors, but not to Brickman. She enrolled…

  16. William Osler and Seymour Thomas, “the boy artist of Texas”

    PubMed Central

    2016-01-01

    Critics consider the 1908–1909 portrait of William Osler by S. Seymour Thomas the best of six oil-on-canvas portraits of Osler done from life, including those by the more acclaimed US artists John Singer Sargent and William Merritt Chase. Osler called it “the best pictorial diagnosis I have ever seen” and told Thomas “I am at your service.” A reappraisal of Seymour Thomas explains why his portrait makes us feel much as the artist did in Osler's presence, which is the original English-language definition of “empathy.” Thomas told his subject that “I feel that you can look clear through me and see the wall on the other side.” The intensity of Osler's gaze affects us similarly. The portrait satisfied Osler, but his wife, Grace Revere Osler, never warmed to it, perhaps because it depicts so clearly a highly focused, agenda-driven man. Helen Thomas used the portrait to promote her husband's business, and, after a tortuous history, the portrait eventually returned to Oxford University, where it now hangs inconspicuously in the Radcliffe Science Library. PMID:27365894

  17. Dr Alexander Graham Bell--audiologist and speech therapist.

    PubMed

    Chakravorty, R C

    1976-09-01

    Alexander Graham Bell is best known for his role in the invention of the telephone. However, he had a lifelong involvement in speech therapy and audiology besides many other medical investigations. He was also awarded an honorary MD degree from Heidelberg University. In this, the 100th anniversary of his invention of the telephone, his life and some of his medical interests are briefly reviewed.

  18. Evidence for the effectiveness of Alexander Technique lessons in medical and health-related conditions: a systematic review.

    PubMed

    Woodman, J P; Moore, N R

    2012-01-01

    Complementary medicine and alternative approaches to chronic and intractable health conditions are increasingly being used, and require critical evaluation. The aim of this review was to systematically evaluate available evidence for the effectiveness and safety of instruction in the Alexander Technique in health-related conditions. PUBMED, EMBASE, PSYCHINFO, ISI Web-of-Knowledge, AMED, CINHAL-plus, Cochrane library and Evidence-based Medicine Reviews were searched to July 2011. Inclusion criteria were prospective studies evaluating Alexander Technique instruction (individual lessons or group delivery) as an intervention for any medical indication/health-related condition. Studies were categorised and data extracted on study population, randomisation method, nature of intervention and control, practitioner characteristics, validity and reliability of outcome measures, completeness of follow-up and statistical analyses.   Of 271 publications identified, 18 were selected: three randomised, controlled trials (RCTs), two controlled non-randomised studies, eight non-controlled studies, four qualitative analyses and one health economic analysis. One well-designed, well-conducted RCT demonstrated that, compared with usual GP care, Alexander Technique lessons led to significant long-term reductions in back pain and incapacity caused by chronic back pain. The results were broadly supported by a smaller, earlier RCT in chronic back pain. The third RCT, a small, well-designed, well-conducted study in individuals with Parkinson's disease, showed a sustained increased ability to carry out everyday activities following Alexander lessons, compared with usual care. The 15 non-RCT studies are also reviewed. Strong evidence exists for the effectiveness of Alexander Technique lessons for chronic back pain and moderate evidence in Parkinson's-associated disability. Preliminary evidence suggests that Alexander Technique lessons may lead to improvements in balance skills in the

  19. Randomised controlled trial of Alexander technique lessons, exercise, and massage (ATEAM) for chronic and recurrent back pain.

    PubMed

    Little, Paul; Lewith, George; Webley, Fran; Evans, Maggie; Beattie, Angela; Middleton, Karen; Barnett, Jane; Ballard, Kathleen; Oxford, Frances; Smith, Peter; Yardley, Lucy; Hollinghurst, Sandra; Sharp, Debbie

    2008-08-19

    To determine the effectiveness of lessons in the Alexander technique, massage therapy, and advice from a doctor to take exercise (exercise prescription) along with nurse delivered behavioural counselling for patients with chronic or recurrent back pain. Factorial randomised trial. 64 general practices in England. 579 patients with chronic or recurrent low back pain; 144 were randomised to normal care, 147 to massage, 144 to six Alexander technique lessons, and 144 to 24 Alexander technique lessons; half of each of these groups were randomised to exercise prescription. Normal care (control), six sessions of massage, six or 24 lessons on the Alexander technique, and prescription for exercise from a doctor with nurse delivered behavioural counselling. Roland Morris disability score (number of activities impaired by pain) and number of days in pain. Exercise and lessons in the Alexander technique, but not massage, remained effective at one year (compared with control Roland disability score 8.1: massage -0.58, 95% confidence interval -1.94 to 0.77, six lessons -1.40, -2.77 to -0.03, 24 lessons -3.4, -4.76 to -2.03, and exercise -1.29, -2.25 to -0.34). Exercise after six lessons achieved 72% of the effect of 24 lessons alone (Roland disability score -2.98 and -4.14, respectively). Number of days with back pain in the past four weeks was lower after lessons (compared with control median 21 days: 24 lessons -18, six lessons -10, massage -7) and quality of life improved significantly. No significant harms were reported. One to one lessons in the Alexander technique from registered teachers have long term benefits for patients with chronic back pain. Six lessons followed by exercise prescription were nearly as effective as 24 lessons. National Research Register N0028108728.

  20. Randomised controlled trial of Alexander technique lessons, exercise, and massage (ATEAM) for chronic and recurrent back pain.

    PubMed

    Little, Paul; Lewith, George; Webley, Fran; Evans, Maggie; Beattie, Angela; Middleton, Karen; Barnett, Jane; Ballard, Kathleen; Oxford, Frances; Smith, Peter; Yardley, Lucy; Hollinghurst, Sandra; Sharp, Debbie

    2008-12-01

    To determine the effectiveness of lessons in the Alexander technique, massage therapy, and advice from a doctor to take exercise (exercise prescription) along with nurse delivered behavioural counselling for patients with chronic or recurrent back pain. Factorial randomised trial. Setting 64 general practices in England. 579 patients with chronic or recurrent low back pain; 144 were randomised to normal care, 147 to massage, 144 to six Alexander technique lessons, and 144 to 24 Alexander technique lessons; half of each of these groups were randomised to exercise prescription. Normal care (control), six sessions of massage, six or 24 lessons on the Alexander technique, and prescription for exercise from a doctor with nurse delivered behavioural counselling. Roland Morris disability score (number of activities impaired by pain) and number of days in pain. Exercise and lessons in the Alexander technique, but not massage, remained effective at one year (compared with control Roland disability score 8.1: massage -0.58, 95% confidence interval -1.94 to 0.77, six lessons -1.40, -2.77 to -0.03, 24 lessons -3.4, -4.76 to -2.03, and exercise -1.29, -2.25 to -0.34). Exercise after six lessons achieved 72% of the effect of 24 lessons alone (Roland disability score -2.98 and -4.14, respectively). Number of days with back pain in the past four weeks were lower after lessons (compared with control median 21 days: 24 lessons -18, six lessons -10, massage -7) and quality of life improved significantly. No significant harms were reported. One to one lessons in the Alexander technique from registered teachers have long term benefits for patients with chronic back pain. Six lessons followed by exercise prescription were nearly as effective as 24 lessons.

  1. A human neurodevelopmental model for Williams syndrome.

    PubMed

    Chailangkarn, Thanathom; Trujillo, Cleber A; Freitas, Beatriz C; Hrvoj-Mihic, Branka; Herai, Roberto H; Yu, Diana X; Brown, Timothy T; Marchetto, Maria C; Bardy, Cedric; McHenry, Lauren; Stefanacci, Lisa; Järvinen, Anna; Searcy, Yvonne M; DeWitt, Michelle; Wong, Wenny; Lai, Philip; Ard, M Colin; Hanson, Kari L; Romero, Sarah; Jacobs, Bob; Dale, Anders M; Dai, Li; Korenberg, Julie R; Gage, Fred H; Bellugi, Ursula; Halgren, Eric; Semendeferi, Katerina; Muotri, Alysson R

    2016-08-18

    Williams syndrome is a genetic neurodevelopmental disorder characterized by an uncommon hypersociability and a mosaic of retained and compromised linguistic and cognitive abilities. Nearly all clinically diagnosed individuals with Williams syndrome lack precisely the same set of genes, with breakpoints in chromosome band 7q11.23 (refs 1-5). The contribution of specific genes to the neuroanatomical and functional alterations, leading to behavioural pathologies in humans, remains largely unexplored. Here we investigate neural progenitor cells and cortical neurons derived from Williams syndrome and typically developing induced pluripotent stem cells. Neural progenitor cells in Williams syndrome have an increased doubling time and apoptosis compared with typically developing neural progenitor cells. Using an individual with atypical Williams syndrome, we narrowed this cellular phenotype to a single gene candidate, frizzled 9 (FZD9). At the neuronal stage, layer V/VI cortical neurons derived from Williams syndrome were characterized by longer total dendrites, increased numbers of spines and synapses, aberrant calcium oscillation and altered network connectivity. Morphometric alterations observed in neurons from Williams syndrome were validated after Golgi staining of post-mortem layer V/VI cortical neurons. This model of human induced pluripotent stem cells fills the current knowledge gap in the cellular biology of Williams syndrome and could lead to further insights into the molecular mechanism underlying the disorder and the human social brain.

  2. Teaching Nuclear Radiation and the Poisoning of Alexander Litvinenko

    ERIC Educational Resources Information Center

    David R. Lapp

    2008-01-01

    The recent international story about the death of the former KGB agent Alexander Litvinenko has more than just a few wondering about radiation poisoning and the sinister sounding polonium-210. I was preparing to begin a nuclear radiation unit the Monday after Thanksgiving 2006. As it turned out, Litvinenko died Thanksgiving Day after a short and…

  3. Alexander Samokutyaev conducts BTKh-14/Bioemulsiya (Bioemulsion) Experiment

    NASA Image and Video Library

    2011-05-05

    ISS027-E-022454 (5 May 2011) --- Russian cosmonaut Alexander Samokutyaev, Expedition 27 flight engineer, uses a glovebox to service the Russian Bioemulsion science payload in the Poisk Mini-Research Module 2 (MRM2) of the International Space Station. The Bioemulsion experiment is attempting to develop faster technologies for obtaining microorganism biomass and biologically active substance biomass for creating highly efficient environmentally pure bacteria, enzymes, and medicinal/pharmaceutical preparations.

  4. Teachers' professional development needs and current practices at the Alexander Science Center School

    NASA Astrophysics Data System (ADS)

    Gargus, Gerald Vincent

    This investigation represents an in-depth understanding of teacher professional development at the Alexander Science Center School, a dependent charter museum school established through a partnership between the California Science Center and Los Angeles Unified School District. Three methods of data collection were used. A survey was distributed and collected from the school's teachers, resulting in a prioritized list of teacher professional development needs, as well as a summary of teachers' opinions about the school's existing professional development program. In addition, six key stakeholders in the school's professional development program were interviewed for the study. Finally, documents related to the school's professional development program were analyzed. Data collected from the interviews and documents were used to develop an understand various components of the Alexander Science Center School's professional development program. Teachers identified seven areas that had a high-priority for future professional development including developing skills far working with below-grade-level students, improving the analytical skills of student in mathematics, working with English Language Learners, improving students' overall reading ability levels, developing teachers' content-area knowledge for science, integrating science across the curriculum, and incorporating hands-on activity-based learning strategies to teach science. Professional development needs identified by Alexander Science Center School teachers were categorized based on their focus on content knowledge, pedagogical content knowledge, or curricular knowledge. Analysis of data collected through interviews and documents revealed that the Alexander Science Center School's professional development program consisted of six venues for providing professional development for teachers including weekly "banked time" sessions taking place within the standard school day, grade-level meetings, teacher support

  5. Obituary: William A. Rense (1914-2008)

    NASA Astrophysics Data System (ADS)

    Cushman, Glen

    2009-12-01

    by large egos, his unassuming manner may have been what made him stand out as a teacher and as a friend. A quote from Alexander Pope seems to fit him: "True politeness consists in being easy one's self, and in making everyone about one as easy as one can. William A. Rense is survived by his wife, Wanda Rense of Estes Park, Colorado, and three sons: William of Estes Park, John of Anchorage, Alaska, and Charles of Los Alamos, New Mexico. A memorial service was held on April 2, 2008, at Good Samaritan Village, Estes Park.

  6. Instructional Strategies to Accommodate a Team-Teaching Approach

    ERIC Educational Resources Information Center

    Gaytan, Jorge

    2010-01-01

    The concept of team teaching is attributed to William Alexander, known as the "father of the American middle school," who delivered a presentation at a 1963 conference held at Cornell University. Alexander's main idea was to establish teams of three to five middle school teachers who would be in charge of team teaching content to large groups of…

  7. A "Large and Graceful Sinuosity": John Herschel's Graphical Method

    NASA Astrophysics Data System (ADS)

    Hankins, Thomas L.

    2006-12-01

    In 1833 John Herschel published a graphical method for determining the orbits of double stars. He argued that this method, which depended on human judgment rather than mathematical analysis, gave better results than computation, given the uncertainty in the data. Herschel found that astronomy and terrestrial physics were especially suitable for graphical treatment, and he expected that graphs would soon become important in all areas of science. He argued with William Whewell and James D. Forbes over the process of induction, over the application of probability, and over the moral content of science. Graphs entered into all these debates, but because they constituted a method, not a metaphysics, they were acceptable to most practicing scientists and became increasingly popular throughout the nineteenth century.

  8. Alexander Bain's CUE in the Post-Modern World: Unity Revisited.

    ERIC Educational Resources Information Center

    Dryden, Phyllis

    In 1866, Alexander Bain proposed that by evaluating unity, coherence, and emphasis (which he brought together under the acronym "CUE"), students could judge the effectiveness of their written paragraphs. One hundred twenty-five years later, the proposition is still central to composition instruction. A review of modern writing textbooks…

  9. Exploring the psychological processes underlying touch: lessons from the Alexander Technique.

    PubMed

    Jones, T; Glover, L

    2014-01-01

    The experience of touch is significant; both in its positive implications and in how it attracts caution and controversy. Accordingly, physical contact within psychological therapy has been shown to improve well-being and the therapeutic relationship, yet the majority of therapists never or rarely use touch. This research aimed to explore psychological processes underlying touch through the Alexander Technique, a psycho-physical technique taught one to one using touch. Six individuals who had received the Alexander Technique were interviewed, and 111 completed surveys. Interview data suggested an incompatibility between touch and the spoken word, which was understood through the way touch lacks verbal discourses in our society. The largely simplistic and dichotomous verbal understanding we have (either only very positive or very negative) could help understand some of the societal-level caution surrounding touch. Touch was seen also as a nurturing experience by interviewees, which influenced inter-personal and intra-personal relational processes. Developmental models were used to frame the way touch strengthened the pupil-teacher relationship and the way pupils' intra-personal psychological change seemed linked to this relational experience. The surveys largely supported these findings, and discussion is made around the notable way pupils negatively interpreted the intention of the survey. Implications for the use of touch in psychological therapies are discussed, as are limitations and ideas for future research. Touch is a powerful experience, and physical contact within psychological therapy has been shown to improve well-being and the therapeutic relationship, yet the majority of therapists never or rarely use touch. The AT is an alternative therapeutic approach to psycho-physical well-being that offers an interesting model to study the impact of touch. Findings from those that have used the technique reaffirmed that touch can improve well-being and can be a

  10. Alexander Kapp--The First Known User of the Andragogy Concept

    ERIC Educational Resources Information Center

    Loeng, Svein

    2017-01-01

    The German gymnasium teacher Alexander Kapp (1800-1869) was to all appearances the first one to use the "andragogy concept" as a term for "adult learning." In 1833 he published the book "Platon's Erziehungslehre, als Pädagogik für die Einzelnen und als Staatspädagogik. Oder dessen praktische Philosophie." This book…

  11. Handedness and corpus callosal morphology in Williams syndrome.

    PubMed

    Martens, Marilee A; Wilson, Sarah J; Chen, Jian; Wood, Amanda G; Reutens, David C

    2013-02-01

    Williams syndrome is a neurodevelopmental genetic disorder caused by a hemizygous deletion on chromosome 7q11.23, resulting in atypical brain structure and function, including abnormal morphology of the corpus callosum. An influence of handedness on the size of the corpus callosum has been observed in studies of typical individuals, but handedness has not been taken into account in studies of callosal morphology in Williams syndrome. We hypothesized that callosal area is smaller and the size of the splenium and isthmus is reduced in individuals with Williams syndrome compared to healthy controls, and examined age, sex, and handedness effects on corpus callosal area. Structural magnetic resonance imaging scans were obtained on 25 individuals with Williams syndrome (18 right-handed, 7 left-handed) and 25 matched controls. We found that callosal thickness was significantly reduced in the splenium of Williams syndrome individuals compared to controls. We also found novel evidence that the callosal area was smaller in left-handed participants with Williams syndrome than their right-handed counterparts, with opposite findings observed in the control group. This novel finding may be associated with LIM-kinase hemizygosity, a characteristic of Williams syndrome. The findings may have significant clinical implications in future explorations of the Williams syndrome cognitive phenotype.

  12. Origin of Silurian reefs in the Alexander Terrane of southeastern Alaska

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Soja, C.M.

    1991-04-01

    Lower to Upper Silurian (upper Llandovery-Ludlow) limestones belonging to the Heceta Formation record several episodes of reef growth in the Alexander terrane of southeastern Alaska. As the oldest carbonates of wide-spread distribution in the region, the Heceta limestones represent the earliest development of a shallow-marine platform within the Alexander arc and the oldest foundation for reef evolution. These deposits provide important insights into the dynamic processes, styles, and bathymetry associated with reef growth in tectonically active oceanic islands. Massive stromatoporoids, corals, and red algae are preserved in fragmental rudstones and represent a fringing reef that formed at the seaward edgemore » of the incipient marine shelf. Accessory constituents in this reef include crinoids and the cyanobacterium Girvanella. Small biostromes were constructed by ramose corals and stromatoporoids on oncolitic substrates in backreef or lagoonal environments. These buildups were associated with low-diversity assemblages of brachiopods and with gastropods, amphiporids, calcareous algae and cyanobacteria. Microbial boundstones reflect the widespread encrustation of cyanobacteria and calcified microproblematica on shelly debris as stromatolitic mats that resulted in the development of a stromatactoid-bearing mud mound and a barrier reef complex. Epiphytaceans, other microbes, and aphrosalpingid sponges were the primary frame-builders of the barrier reefs. These buildups attained significant relief at the shelf margin and shed detritus as slumped blocks and debris flows into deep-water sites along the slope. The similarity of these stromatolitic-aphrosalpingid reefs to those from Siluro-Devonian strata of autochthonous southwestern Alaska suggests paleobiogeographic ties of the Alexander terrane to cratonal North America during the Silurian.« less

  13. 33 CFR 167.1700 - In Prince William Sound: General.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 2 2014-07-01 2014-07-01 false In Prince William Sound: General... Schemes and Precautionary Areas Pacific West Coast § 167.1700 In Prince William Sound: General. The Prince William Sound Traffic Separation Scheme consists of four parts: Prince William Sound Traffic Separation...

  14. 33 CFR 167.1700 - In Prince William Sound: General.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false In Prince William Sound: General... Schemes and Precautionary Areas Pacific West Coast § 167.1700 In Prince William Sound: General. The Prince William Sound Traffic Separation Scheme consists of four parts: Prince William Sound Traffic Separation...

  15. 33 CFR 167.1700 - In Prince William Sound: General.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false In Prince William Sound: General... Schemes and Precautionary Areas Pacific West Coast § 167.1700 In Prince William Sound: General. The Prince William Sound Traffic Separation Scheme consists of four parts: Prince William Sound Traffic Separation...

  16. 33 CFR 167.1700 - In Prince William Sound: General.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false In Prince William Sound: General... Schemes and Precautionary Areas Pacific West Coast § 167.1700 In Prince William Sound: General. The Prince William Sound Traffic Separation Scheme consists of four parts: Prince William Sound Traffic Separation...

  17. Robin Williams' suicide: a case study.

    PubMed

    Tohid, Hassaan

    2016-01-01

    The world renowned comedian and four-time Oscar nominated actor Robin Williams died on August 11, 2014. From the outset, the news indicated that his death was believed to be a suicide and this was later confirmed to be true by the autopsy reports. Williams had been suffering from severe depression, which is believed to be the leading contributor to his suicide. In this case study, I will highlight the event of the actor's suicide and the main risk factors along with depression leading to his tragic death. As of the end of 2015, no other case study seemed to have addressed or explored the links between the cause (or causes) and events leading to Robin Williams' suicide. Robin Williams was suffering from relationship problems, financial problems, drug addiction, and major depression. All of these factors led to his suicide. The chances of committing suicide drastically increase in the presence of any of the key risk factors. Unfortunately, the actor Robin Williams was dealing with four of the major risk factors all together, which put him at a high risk of committing suicide and eventually led to his tragic death.

  18. Teachers of the Alexander Technique in the UK and the people who take their lessons: A national cross-sectional survey.

    PubMed

    Eldred, J; Hopton, A; Donnison, E; Woodman, J; MacPherson, H

    2015-06-01

    Given the rising profile of the Alexander Technique in the UK, there is a need for a comprehensive description of its teachers and of those who currently take lessons. In a national survey of Alexander teachers, we set out to address this information gap. A cross-sectional survey of 871 UK members of three main Alexander Technique teachers' professional associations was conducted. A questionnaire requested information about their professional background, teaching practice and methods, and about the people who attend lessons and their reasons for seeking help. With an overall response rate of 61%, 534 teachers responded; 74% were female with median age of 58 years, 60% had a higher education qualification, and 95% were self-employed, many with additional non-Alexander paid employment. The majority (87%) offered lessons on their own premises or in a privately rented room, and 19% provided home visits; both individual and group lessons were provided. People who took lessons were predominantly female (66%) with a median age of 48 years, and 91% paid for their lessons privately. Nearly two-thirds (62%) began lessons for reasons related to musculoskeletal conditions, including back symptoms, posture, neck pain, and shoulder pain. Other reasons were general (18%, including well-being), performance-related (10%, including voice-, music-, and sport-related), psychological (5%) and neurological (3%). We estimate that Alexander teachers in the UK provide approximately 400,000 lessons per year. This study provides an overview of Alexander Technique teaching in the UK today and data that may be useful when planning future research. Copyright © 2015 Elsevier Ltd. All rights reserved.

  19. Participating in and delivering the ATEAM trial (Alexander technique lessons, exercise, and massage) interventions for chronic back pain: A qualitative study of professional perspectives.

    PubMed

    Beattie, Angela; Shaw, Alison; Yardley, Lucy; Little, Paul; Sharp, Debbie

    2010-01-01

    To outline professionals' experiences of participation, perceived benefits and acceptability of the interventions delivered in the ATEAM trial (Alexander technique lessons, exercise, and massage), for patients with chronic or recurrent back pain. Qualitative study using in-depth interviews was conducted with a purposeful sample of twenty professionals (general practitioners (GPs), nurses, Alexander technique teachers, and massage therapists). Data were recorded, transcribed, and analysed thematically using the constant comparison method. Evidence of effectiveness GPs wanted an evidence base for the interventions, whilst nurses, Alexander technique teachers and massage therapists perceived patient reports of benefit as evidence. Professionals' perception of the acceptability of the intervention: professional perspectives differed, with GPs and nurses viewing the structured nature of exercise prescription and Alexander technique lessons as more beneficial and acceptable than massage in alleviating patients' back pain. Economic cost: the cost to patients pursuing Alexander technique lessons and massage was perceived to be a barrier outside the trial. Inter-professional communication: there was little communication between the professionals groups within the trial. Valuable insights have been gained into the perceived benefits and acceptability of exercise, Alexander technique lessons and massage as interventions for chronic back pain. Lessons in the Alexander technique with or without exercise, was perceived as more beneficial and acceptable than massage by professionals who participated and delivered the ATEAM trial interventions. Copyright 2010 Elsevier Ltd. All rights reserved.

  20. View west of the James and Lucy Alexander gravestone and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View west of the James and Lucy Alexander gravestone and family plot among other demarcated family plots in the Female Union Band Cemetery. - Mount Zion Cemetery/ Female Union Band Cemetery, Bounded by 27th Street right-of-way N.W. (formerly Lyons Mill Road), Q Street N.W., & Mill Road N.W., Washington, District of Columbia, DC

  1. Dr. Alexander Garden, a Linnaean in colonial America, and the saga of five "electric eels".

    PubMed

    Finger, Stanley

    2010-01-01

    Alexander Garden (1730-1791) was born in Scotland, where he trained in medicine before settling in South Carolina in 1752. With a passion for collecting and a love of nature, he sent specimens to Linnaeus and his associates in Europe. In 1774, Garden observed and conducted electrical experiments on some "eels" that had survived the trip from Surinam to Charleston. His detailed observations and reasons for believing they emit electricity were read before the Royal Society of London and subsequently published. He also advised the sea captain who owned the eels on how to preserve them and where to deliver their bodies if they died en route to London. Although they did die en route, John Hunter of the Royal Society was able to provide excellent descriptions of their electric organs because they were so well preserved. The sequence of events that followed led to other live eels surviving the voyage to London, where they were observed to spark in darkness in 1776. This was a critical piece of evidence in favor of fish electricity and eventually for the more revolutionary idea that even human nerves and muscles might function electrically.

  2. What motion is: William Neile and the laws of motion.

    PubMed

    Kemeny, Max

    2017-07-01

    In 1668-1669 William Neile and John Wallis engaged in a protracted correspondence regarding the nature of motion. Neile was unhappy with the laws of motion that had been established by the Royal Society in three papers published in 1668, deeming them not explanations of motion at all, but mere descriptions. Neile insisted that science could not be informative without a discussion of causes, meaning that Wallis's purely kinematic account of collision could not be complete. Wallis, however, did not consider Neile's objections to his work to be serious. Rather than engage in a discussion of the proper place of natural philosophy in science, Wallis decided to show how Neile's preferred treatment of motion lead to absurd conclusions. This dispute is offered as a case study of dispute resolution within the early Royal Society.

  3. Alexander Williamson and the modernisation of Japan.

    PubMed

    Davies, Alwyn G

    2015-01-01

    One hundred and fifty years ago, five students were smuggled out of feudal Japan and came to London to learn Western technology, governance, and economics. They were put into the care of Alexander Williamson, who was Professor of Chemistry at University College London, and when they went back they, and the students who followed them, became the founders of the modern Japanese state. This is the British side of that remarkable story. Williamson's career and chemistry are briefly reviewed, followed by an account of the students' presence in Britain, and then the commemoration of the sesquicentenary of these events.

  4. An Occupation for an Independent Gentleman - Astronomy in the Life of Herschel, John

    NASA Astrophysics Data System (ADS)

    Chapman, Allan

    Sir John Frederick William Herschel occupies a pivotal position in the history of British astronomy (1). He formed the living link between two styles or traditions of science by being the last major specimen of one breed, and the inspiration and intellectual role model for the generation that would follow. For John Herschel was perhaps the last significant figure to devote himself wholly and full-time to fundamental research in astronomy and its related sciences on the strength of a private fortune. And while the stature that he enjoyed did much to stimulate the concept of the 'professional' astronomer in Britain, so many of these men of the rising generation who admired his thorough-going dedication to science were themselves more obviously professional in the respect that they earned their livings through academic science. One sees in him, therefore, an eclectic blend of attitudes towards what science was, how it should be pursued, and how it should be paid for.

  5. "In the Footsteps of Alexander the Great" PBS Series. Teacher's Guide.

    ERIC Educational Resources Information Center

    Corporation for Public Broadcasting, Washington, DC.

    This teacher's guide correlates with the Public Broadcasting Service (PBS) television series "In the Footsteps of Alexander the Great" hosted by historian Michael Wood. The four episodes of the series are entitled: "Son of God"; "Lord of Asia"; "Across the Hindu Kush"; and "To the Ends of the…

  6. Science, Education, and Antebellum Reform: The Case of Alexander Dallas Bache.

    ERIC Educational Resources Information Center

    Slotten, Hugh R.

    1991-01-01

    Suggest that science and formal education became the primary civilizing forces in the decades preceding the Civil War. Focuses on the work of scientist and educational reformer Alexander Dallas Bache. Concludes that Bache's efforts to promote unified public schools, scientific and technical education, and moral training inspired later Progressive…

  7. An economic evaluation of Alexander Technique lessons or acupuncture sessions for patients with chronic neck pain: A randomized trial (ATLAS).

    PubMed

    Essex, Holly; Parrott, Steve; Atkin, Karl; Ballard, Kathleen; Bland, Martin; Eldred, Janet; Hewitt, Catherine; Hopton, Ann; Keding, Ada; Lansdown, Harriet; Richmond, Stewart; Tilbrook, Helen; Torgerson, David; Watt, Ian; Wenham, Aniela; Woodman, Julia; MacPherson, Hugh

    2017-01-01

    To assess the cost-effectiveness of acupuncture and usual care, and Alexander Technique lessons and usual care, compared with usual GP care alone for chronic neck pain patients. An economic evaluation was undertaken alongside the ATLAS trial, taking both NHS and wider societal viewpoints. Participants were offered up to twelve acupuncture sessions or twenty Alexander lessons (equivalent overall contact time). Costs were in pounds sterling. Effectiveness was measured using the generic EQ-5D to calculate quality adjusted life years (QALYs), as well as using a specific neck pain measure-the Northwick Park Neck Pain Questionnaire (NPQ). In the base case analysis, incremental QALY gains were 0.032 and 0.025 in the acupuncture and Alexander groups, respectively, in comparison to usual GP care, indicating moderate health benefits for both interventions. Incremental costs were £451 for acupuncture and £667 for Alexander, mainly driven by intervention costs. Acupuncture was likely to be cost-effective (ICER = £18,767/QALY bootstrapped 95% CI £4,426 to £74,562) and was robust to most sensitivity analyses. Alexander lessons were not cost-effective at the lower NICE threshold of £20,000/QALY (£25,101/QALY bootstrapped 95% CI -£150,208 to £248,697) but may be at £30,000/QALY, however, there was considerable statistical uncertainty in all tested scenarios. In comparison with usual care, acupuncture is likely to be cost-effective for chronic neck pain, whereas, largely due to higher intervention costs, Alexander lessons are unlikely to be cost-effective. However, there were high levels of missing data and further research is needed to assess the long-term cost-effectiveness of these interventions.

  8. Identification of metapopulation dynamics among Northern Goshawks of the Alexander Archipelago, Alaska, and Coastal British Columbia

    USGS Publications Warehouse

    Sonsthagen, Sarah A.; McClaren, Erica L.; Doyle, Frank I.; Titus, K.; Sage, George K.; Wilson, Robert E.; Gust, Judy R.; Talbot, Sandra L.

    2012-01-01

    Northern Goshawks occupying the Alexander Archipelago, Alaska, and coastal British Columbia nest primarily in old-growth and mature forest, which results in spatial heterogeneity in the distribution of individuals across the landscape. We used microsatellite and mitochondrial data to infer genetic structure, gene flow, and fluctuations in population demography through evolutionary time. Patterns in the genetic signatures were used to assess predictions associated with the three population models: panmixia, metapopulation, and isolated populations. Population genetic structure was observed along with asymmetry in gene flow estimates that changed directionality at different temporal scales, consistent with metapopulation model predictions. Therefore, Northern Goshawk assemblages located in the Alexander Archipelago and coastal British Columbia interact through a metapopulation framework, though they may not fit the classic model of a metapopulation. Long-term population sources (coastal mainland British Columbia) and sinks (Revillagigedo and Vancouver islands) were identified. However, there was no trend through evolutionary time in the directionality of dispersal among the remaining assemblages, suggestive of a rescue-effect dynamic. Admiralty, Douglas, and Chichagof island complex appears to be an evolutionarily recent source population in the Alexander Archipelago. In addition, Kupreanof island complex and Kispiox Forest District populations have high dispersal rates to populations in close geographic proximity and potentially serve as local source populations. Metapopulation dynamics occurring in the Alexander Archipelago and coastal British Columbia by Northern Goshawks highlight the importance of both occupied and unoccupied habitats to long-term population persistence of goshawks in this region.

  9. 46. Photocopy of photograph (Pentran file), (from Alexander Brown's Peninsula's ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    46. Photocopy of photograph (Pentran file), (from Alexander Brown's Peninsula's Last Street Cars, Daily Press, January 15, 1956) photographer unknown. The first streetcar (with dignitaries) to make the run from Newport News to a new housing development named Hilton Village in September 1918. - Newport News & Old Point Railway & Electric Company, Trolley Barn & Administration Building, 3400 Victoria Boulevard, Hampton, Hampton, VA

  10. John Dalton and the origin of the atomic theory: reassessing the influence of Bryan Higgins.

    PubMed

    Grossman, Mark I

    2017-12-01

    During the years 1814-1819, William Higgins, an Irish chemist who worked at the Dublin Society, claimed he had anticipated John Dalton in developing the atomic theory and insinuated that Dalton was a plagiarist. This essay focuses not on William Higgins, but on his uncle Bryan Higgins, a well-known chemist of his day, who had developed his own theories of caloric and chemical combination, similar in many respects to that of Dalton. New evidence is first introduced addressing Bryan's disappearance from the scientific community after 1803. In his later years, Bryan apparently suffered from a condition resulting in a decline in his mental health, which explains why he never lodged any priority claims of his own against Dalton, or defended those of his nephew. Dalton's mention of Bryan's name in Part II of A New System of Chemical Philosophy, his laboratory notebook entries, and a fresh look at his correspondence with chemist Thomas Charles Hope indicate that Dalton adopted a Higgins-like caloric model in 1803. Together these factors provide evidence to support the argument that Dalton learned of Bryan's theories via a meeting he had with William Allen on 10 July 1803. Existing evidence related to the origin of the atomic theory is worthy of re-examination in light of Dalton's possible prior knowledge of Bryan's work.

  11. Interview with Alexander Cohen.

    PubMed

    Cohen, Alexander Ander

    2017-05-01

    Ander Cohen speaks to Adam Price-Evans, Commissioning Editor of Future Cardiology: Alexander (Ander) Cohen MBBS (Hons), MSc, MD, FRACP is a vascular physician and epidemiologist at Guy's and St Thomas' Hospital, King's College (London, UK). He graduated with honors in medicine and honors in surgery from the University of Melbourne, Australia, and became a fellow of the Royal Australasian College of Physicians in 1990. He was awarded an MSc in Epidemiology from the London School of Hygiene and Tropical Medicine, University of London in 1991 with a thesis on the metabolic syndrome in South-Asian populations. In 1998, he was awarded an MD with a thesis on the epidemiology of venous thromboembolism and thromboprophylaxis. In addition to his clinical work, he is involved in designing, managing and analyzing clinical trials from Phase I to IV. He is the Chairman and a member of many international steering committees for multicenter trials, epidemiological and pharmacoeconomic studies, and was previously the Director of Clinical Research and an Epidemiologist in Thrombosis Research at King's College Hospital.

  12. 33 CFR 110.233 - Prince William Sound, Alaska.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 1 2014-07-01 2014-07-01 false Prince William Sound, Alaska. 110... ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.233 Prince William Sound, Alaska. (a) The anchorage grounds. In Prince William Sound, Alaska, beginning at a point at latitude 60°40′00″ N., longitude 146°40...

  13. 33 CFR 110.233 - Prince William Sound, Alaska.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 1 2012-07-01 2012-07-01 false Prince William Sound, Alaska. 110... ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.233 Prince William Sound, Alaska. (a) The anchorage grounds. In Prince William Sound, Alaska, beginning at a point at latitude 60°40′00″ N., longitude 146°40...

  14. 33 CFR 110.233 - Prince William Sound, Alaska.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 1 2013-07-01 2013-07-01 false Prince William Sound, Alaska. 110... ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.233 Prince William Sound, Alaska. (a) The anchorage grounds. In Prince William Sound, Alaska, beginning at a point at latitude 60°40′00″ N., longitude 146°40...

  15. 33 CFR 110.233 - Prince William Sound, Alaska.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Prince William Sound, Alaska. 110... ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.233 Prince William Sound, Alaska. (a) The anchorage grounds. In Prince William Sound, Alaska, beginning at a point at latitude 60°40′00″ N., longitude 146°40...

  16. 33 CFR 110.233 - Prince William Sound, Alaska.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false Prince William Sound, Alaska. 110... ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.233 Prince William Sound, Alaska. (a) The anchorage grounds. In Prince William Sound, Alaska, beginning at a point at latitude 60°40′00″ N., longitude 146°40...

  17. Clinical Experience in Late Antiquity: Alexander of Tralles and the Therapy of Epilepsy

    PubMed Central

    Bouras-vallianatos, Petros

    2014-01-01

    Alexander of Tralles, writing in the late sixth century, combined his wide-ranging practical knowledge with earlier medical theories. This article shows how clinical experience is used in Alexander’s works by concentrating on his therapeutic advice on epilepsy and, in particular, on pharmacology and the group of so-called natural remedies. I argue that clinical testing is used not only for the introduction of new medicines but also as an instrument for checking the therapeutic effect of popular healing practices. On another level, this article discusses Alexander’s role as the author of a medical compendium; it suggests that by marking the cases of clinical testing with a set of recurrent expressions, Alexander leads his audience to reflect on his medical authority and personal contribution. PMID:25045178

  18. [Urology and National Socialism: the fate of Alexander von Lichtenberg 1880-1949].

    PubMed

    Moll, F H; Krischel, M; Rathert, P; Fangerau, H

    2010-09-01

    Alexander von Lichtenberg (1880-1949) was one of the famous members of the German Urological Society (DGU) in pre-war Germany. He introduced excretion urography and a special TURP Instrument. In 1928 he was president of the 8th meeting held in the German capital Berlin. His Handbook of Urology, released by Ferdinand Springer publishing house, was a trendsetter in establishing urology as a specialty in Germany and bringing together the whole wisdom of all aspects of urology. He was the founder of the famous Maximilian Nitze Award of the DGU. As a Jew he-like many others-was forced to leave Nazi Germany after 1933. Even in Hungary, his native country, he again had to resist anti-Semitic hostility. Later on he lived in Mexico. Alexander von Lichtenberg has to be remembered with special focus on the exodus of German Jewish scientists during the Nazi time.

  19. An economic evaluation of Alexander Technique lessons or acupuncture sessions for patients with chronic neck pain: A randomized trial (ATLAS)

    PubMed Central

    Essex, Holly; Parrott, Steve; Atkin, Karl; Ballard, Kathleen; Bland, Martin; Eldred, Janet; Hewitt, Catherine; Hopton, Ann; Keding, Ada; Lansdown, Harriet; Richmond, Stewart; Tilbrook, Helen; Torgerson, David; Watt, Ian; Wenham, Aniela; Woodman, Julia; MacPherson, Hugh

    2017-01-01

    Objectives To assess the cost-effectiveness of acupuncture and usual care, and Alexander Technique lessons and usual care, compared with usual GP care alone for chronic neck pain patients. Methods An economic evaluation was undertaken alongside the ATLAS trial, taking both NHS and wider societal viewpoints. Participants were offered up to twelve acupuncture sessions or twenty Alexander lessons (equivalent overall contact time). Costs were in pounds sterling. Effectiveness was measured using the generic EQ-5D to calculate quality adjusted life years (QALYs), as well as using a specific neck pain measure–the Northwick Park Neck Pain Questionnaire (NPQ). Results In the base case analysis, incremental QALY gains were 0.032 and 0.025 in the acupuncture and Alexander groups, respectively, in comparison to usual GP care, indicating moderate health benefits for both interventions. Incremental costs were £451 for acupuncture and £667 for Alexander, mainly driven by intervention costs. Acupuncture was likely to be cost-effective (ICER = £18,767/QALY bootstrapped 95% CI £4,426 to £74,562) and was robust to most sensitivity analyses. Alexander lessons were not cost-effective at the lower NICE threshold of £20,000/QALY (£25,101/QALY bootstrapped 95% CI -£150,208 to £248,697) but may be at £30,000/QALY, however, there was considerable statistical uncertainty in all tested scenarios. Conclusions In comparison with usual care, acupuncture is likely to be cost-effective for chronic neck pain, whereas, largely due to higher intervention costs, Alexander lessons are unlikely to be cost-effective. However, there were high levels of missing data and further research is needed to assess the long-term cost-effectiveness of these interventions. PMID:29211741

  20. 77 FR 45331 - Prince William Sound Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-31

    ... DEPARTMENT OF AGRICULTURE Forest Service Prince William Sound Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Prince William Sound Resource Advisory... Prince William Sound Resource Advisory Committee (RAC) will be discussing and voting on proposals that...

  1. 76 FR 1130 - Prince William Sound Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-07

    ... DEPARTMENT OF AGRICULTURE Forest Service Prince William Sound Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Prince William Sound Resource Advisory... conducted: The Prince William Sound Resource Advisory Committee (RAC) will be discussing and voting on...

  2. Maniac Talk - Dr. William Lau

    NASA Image and Video Library

    2014-01-24

    William Lau Maniac Lecture, 24 January, 2014 Dr. William Lau, Deputy Director for Atmospheres, Earth Science Division at NASA Goddard, presented a Maniac Talk entitled "My Story: A Tale of Three Continents." Bill shared his early childhood under a colonial education system with strong Chinese cultural influence and how world events, cultural and education system of three major continents, Europe, Asia and North America shaped his upbringing career goals and work ethics.

  3. 76 FR 18715 - Prince William Sound Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-05

    ... DEPARTMENT OF AGRICULTURE Forest Service Prince William Sound Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Prince William Sound Resource Advisory... meeting is open to the public. The following business will be conducted: The Prince William Sound Resource...

  4. 33 CFR 167.1700 - In Prince William Sound: General.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... (CONTINUED) PORTS AND WATERWAYS SAFETY OFFSHORE TRAFFIC SEPARATION SCHEMES Description of Traffic Separation Schemes and Precautionary Areas Pacific West Coast § 167.1700 In Prince William Sound: General. The Prince William Sound Traffic Separation Scheme consists of four parts: Prince William Sound Traffic Separation...

  5. William Russell on Schools in Bulgaria

    ERIC Educational Resources Information Center

    Popov, Nikolay; Sabic-El-Rayess, Amra

    2013-01-01

    William Russell became one of the most influential educators in the field of international and comparative education in the first half of the 20th century. In 1914, William Russell obtained his PhD from Teachers College and, within few years, became a prominent figure internationally. He traveled through Europe and taught in Japan and Siberia, as…

  6. Lithium Decreases Glial Fibrillary Acidic Protein in a Mouse Model of Alexander Disease

    PubMed Central

    LaPash Daniels, Christine M.; Paffenroth, Elizabeth; Austin, Elizabeth V.; Glebov, Konstantin; Lewis, Diana; Walter, Jochen; Messing, Albee

    2015-01-01

    Alexander disease is a fatal neurodegenerative disease caused by mutations in the astrocyte intermediate filament glial fibrillary acidic protein (GFAP). The disease is characterized by elevated levels of GFAP and the formation of protein aggregates, known as Rosenthal fibers, within astrocytes. Lithium has previously been shown to decrease protein aggregates by increasing the autophagy pathway for protein degradation. In addition, lithium has also been reported to decrease activation of the transcription factor STAT3, which is a regulator of GFAP transcription and astrogliogenesis. Here we tested whether lithium treatment would decrease levels of GFAP in a mouse model of Alexander disease. Mice with the Gfap-R236H point mutation were fed lithium food pellets for 4 to 8 weeks. Four weeks of treatment with LiCl at 0.5% in food pellets decreased GFAP protein and transcripts in several brain regions, although with mild side effects and some mortality. Extending the duration of treatment to 8 weeks resulted in higher mortality, and again with a decrease in GFAP in the surviving animals. Indicators of autophagy, such as LC3, were not increased, suggesting that lithium may decrease levels of GFAP through other pathways. Lithium reduced the levels of phosphorylated STAT3, suggesting this as one pathway mediating the effects on GFAP. In conclusion, lithium has the potential to decrease GFAP levels in Alexander disease, but with a narrow therapeutic window separating efficacy and toxicity. PMID:26378915

  7. Cultivating Hygiene as a Science: The Welch-Rose Report's Influence at Johns Hopkins and Beyond.

    PubMed

    Thomas, Karen Kruse

    2016-03-01

    In 1915, William Henry Welch and Wickliffe Rose submitted a report to the Rockefeller Foundation that became the template for public health professional education in the United States and abroad. Based on the Welch-Rose Report's recommendations, the Foundation awarded a grant to Johns Hopkins University in 1916 to establish the first independent graduate school of public health, with Welch serving as the founding dean. The Welch-Rose Report and, by extension, the Johns Hopkins School of Hygiene and Public Health established and transmitted a new model of scientific training that wove the laboratory mindset together with the methods of public health administration and epidemiologic fieldwork. During the School's first quarter-century, faculty and alumni were remarkably active in frontline public health problem-solving, as well as launching public health agencies and schools of all types and sizes. The most lasting contribution of the Welch-Rose Report and the Johns Hopkins School of Hygiene and Public Health, now the Johns Hopkins Bloomberg School of Public Health, has been to "cultivate the science of hygiene" to bring about exponential growth in the evidence base for public health. The schools that have adopted the Johns Hopkins model of public health education worldwide have produced professionals who have worked to achieve wide-ranging reforms dedicated to preserving life, protecting health, and preventing injury across populations and continents. © The Author 2016. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  8. Williams-Beuren's Syndrome: A Case Report.

    PubMed

    Zamani, Hassan; Babazadeh, Kazem; Fattahi, Saeid; Mokhtari-Esbuie, Farzad

    2012-01-01

    Williams-Beuren syndrome is a rare familial multisystem disorder occurring in 1 per 20,000 live births. It is characterized by congenital heart defects (CHD), skeletal and renal anomalies, cognitive disorder, social personality disorder and dysmorphic facies. We present a case of Williams syndrome that presented to us with heart murmur and cognitive problem. A 5-year-old girl referred to pediatric cardiologist because of heart murmurs. She had a systolic murmur (2-3/6) in right upper sternal border with radiation to right cervical region. She also had a bulge forehead. Angiography showed mild supra valvular aortic stenosis and mild multiple peripheral pulmonary stenosis. Fluorescent in situ hybridization (FISH) was performed and the result was: 46.XX, ish del (7q11.2) (ELN X1) (7q22 X2) ELN deletion compatible with Williams syndrome. Peripheral pulmonary artery stenosis is associated with Noonan syndrome, Alagille syndrome, Cutis laxa, Ehler-Danlos syndrome, and Silver-Russel syndrome. The patient had peripheral pulmonary artery stenosis, but no other signs of these syndromes were present, and also she had a supravalvular aortic stenosis which was not seen in other syndromes except Williams syndrome. Conclusion. According to primary symptoms, paraclinical and clinical finding such as dysmorphic facies, cognitive disorder and congenital heart defect, Williams syndrome was the first diagnosis. We suggest a more attention for evaluating heart murmur in childhood period, especially when the patient has abnormal facial features or mental problem.

  9. Williams-Beuren's Syndrome: A Case Report

    PubMed Central

    Zamani, Hassan; Babazadeh, Kazem; Fattahi, Saeid; Mokhtari-Esbuie, Farzad

    2012-01-01

    Williams-Beuren syndrome is a rare familial multisystem disorder occurring in 1 per 20,000 live births. It is characterized by congenital heart defects (CHD), skeletal and renal anomalies, cognitive disorder, social personality disorder and dysmorphic facies. We present a case of Williams syndrome that presented to us with heart murmur and cognitive problem. A 5-year-old girl referred to pediatric cardiologist because of heart murmurs. She had a systolic murmur (2-3/6) in right upper sternal border with radiation to right cervical region. She also had a bulge forehead. Angiography showed mild supra valvular aortic stenosis and mild multiple peripheral pulmonary stenosis. Fluorescent in situ hybridization (FISH) was performed and the result was: 46.XX, ish del (7q11.2) (ELN X1) (7q22 X2) ELN deletion compatible with Williams syndrome. Peripheral pulmonary artery stenosis is associated with Noonan syndrome, Alagille syndrome, Cutis laxa, Ehler-Danlos syndrome, and Silver-Russel syndrome. The patient had peripheral pulmonary artery stenosis, but no other signs of these syndromes were present, and also she had a supravalvular aortic stenosis which was not seen in other syndromes except Williams syndrome. Conclusion. According to primary symptoms, paraclinical and clinical finding such as dysmorphic facies, cognitive disorder and congenital heart defect, Williams syndrome was the first diagnosis. We suggest a more attention for evaluating heart murmur in childhood period, especially when the patient has abnormal facial features or mental problem. PMID:22927862

  10. Structural controls on ground-water conditions and estimated aquifer properties near Bill Williams Mountain, Williams, Arizona

    USGS Publications Warehouse

    Pierce, Herbert A.

    2001-01-01

    As of 1999, surface water collected and stored in reservoirs is the sole source of municipal water for the city of Williams. During 1996 and 1999, reservoirs reached historically low levels. Understanding the ground-water flow system is critical to managing the ground-water resources in this part of the Coconino Plateau. The nearly 1,000-meter-deep regional aquifer in the Redwall and Muav Limestones, however, makes studying or utilizing the resource difficult. Near-vertical faults and complex geologic structures control the ground-water flow system on the southwest side of the Kaibab Uplift near Williams, Arizona. To address the hydrogeologic complexities in the study area, a suite of techniques, which included aeromagnetic, gravity, square-array resistivity, and audiomagnetotelluric surveys, were applied as part of a regional study near Bill Williams Mountain. Existing well data and interpreted geophysical data were compiled and used to estimate depths to the water table and to prepare a potentiometric map. Geologic characteristics, such as secondary porosity, coefficient of anisotropy, and fracture-strike direction, were calculated at several sites to examine how these characteristics change with depth. The 14-kilometer-wide, seismically active northwestward-trending Cataract Creek and the northeastward-trending Mesa Butte Fault systems intersect near Bill Williams Mountain. Several north-south-trending faults may provide additional block faulting north and west of Bill Williams Mountain. Because of the extensive block faulting and regional folding, the volcanic and sedimentary rocks are tilted toward one or more of these faults. These faults provide near-vertical flow paths to the regional water table. The nearly radial fractures allow water that reaches the regional aquifer to move away from the Bill Williams Mountain area. Depth to the regional aquifer is highly variable and depends on location and local structures. On the basis of interpreted

  11. Connect the Book. Always Inventing: A Photobiography of Alexander Graham Bell

    ERIC Educational Resources Information Center

    Brodie, Carolyn S.

    2004-01-01

    Cell phones, video phones, voice messaging?one wonders what Alexander Graham Bell would have thought about the many venues today for electronic communication with one another. Bell's March 10, 1876 invention is now 128 years old, but there is no doubt that Bell's "talking machine" changed the world. This article presents a brief review of the…

  12. 78 FR 53630 - Airworthiness Directives; Alexander Schleicher GmbH & Co. Segelflugzeugbau Sailplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-30

    ... rod for conformity following Alexander Schleicher Automatischer H[ouml]henruderanschlu[beta] (English... Manual (CAM) 18, Maintenance, Repair, And Alteration, Of Airframes, Powerplants, Propellers, And...--and-- Guidance--Library/rgccab.nsf/0/41df1277f2dc7e0e86257bcf005112bf/ $FILE/CAM--18--1959.pdf...

  13. Alexander von Humboldt and the concept of animal electricity.

    PubMed

    Kettenmann, H

    1997-06-01

    More than two hundred years ago, Alexander von Humboldt helped to establish Galvani's view that muscle and nerve tissue are electrically excitable. His 1797 publication was a landmark for establishing the concept of animal electricity. Almost half a century later, von Humboldt became the mentor of the young du Bois-Reymond. With the help of von Humboldt's promotion, du Bois-Reymond demonstrated convincingly that animal tissue has the intrinsic capacity to generate electrical activity, and thus laid the ground for modern electrophysiology.

  14. A Disciplinary Immigrant. Alexander Smith at the University of Chicago, 1894-1911

    ERIC Educational Resources Information Center

    Cotter, Donald

    2008-01-01

    The publication in 1906 of Alexander Smith's "Introduction to general inorganic chemistry" inaugurated a decisive change in chemical pedagogy in the US, the effects of which are still evident. The nature and extent of Smith's innovations are described through a comparison of his text to its source material and contemporaries. His…

  15. Geohydrology and water-chemistry of the Alexander Valley, Sonoma County, California

    USGS Publications Warehouse

    Metzger, Loren F.; Farrar, Christopher D.; Koczot, Kathryn M.; Reichard, Eric G.

    2006-01-01

    This study of the geohydrology and water chemistry of the Alexander Valley, California, was done to provide an improved scientific basis for addressing emerging water-management issues, including potential increases in water demand and changes in flows in the Russian River. The study tasks included (1) evaluation of existing geohydrological, geophysical, and geochemical data; (2) collection and analysis of new geohydrologic data, including subsurface lithologic data, ground-water levels, and streamflow records; and (3) collection and analysis of new water-chemistry data. The estimated total water use for the Alexander Valley for 1999 was approximately 15,800 acre-feet. About 13,500 acre-feet of this amount was for agricultural use, primarily vineyards, and about 2,300 acre-feet was for municipal/industrial use. Ground water is the main source of water supply for this area. The main sources of ground water in the Alexander Valley are the Quaternary alluvial deposits, the Glen Ellen Formation, and the Sonoma Volcanics. The alluvial units, where sufficiently thick and saturated, comprise the best aquifer in the study area. Average recharge to the Alexander Valley is estimated from a simple, basinwide water budget. On the basis of an estimated annual average of 298,000 acre-feet of precipitation, 160,000 acre-feet of runoff, and 113,000 to 133,000 acre-feet of evapotranspiration, about 5,000 to 25,000 acre-feet per year is available for ground-water recharge. Because this estimate is based on differences between large numbers, there is significant uncertainty in this recharge estimate. Long-term changes in ground-water levels are evident in parts of the study area, but because of the sparse network and lack of data on well construction and lithology, it is uncertain if any significant changes have occurred in the northern part of the study area since 1980. In the southern half of the study area, ground-water levels generally were lower at the end of the 2002 irrigation

  16. Developing Therapies for Brain Tumors: The Impact of the Johns Hopkins Hunterian Neurosurgical Research Laboratory.

    PubMed

    Brem, Henry; Sankey, Eric W; Liu, Ann; Mangraviti, Antonella; Tyler, Betty M

    2017-01-01

    The Johns Hopkins Hunterian Neurosurgical Laboratory at the Johns Hopkins University School of Medicine was created in 1904 by Harvey Cushing and William Halsted and has had a long history of fostering surgical training, encouraging basis science research, and facilitating translational application. Over the past 30 years, the laboratory has addressed the paucity of brain tumor therapies. Pre-clinical work from the laboratory led to the development of carmustine wafers with initial US Food and Drug Administration (FDA) approval in 1996. Combining carmustine wafers, radiation, and temozolomide led to a significant increase in the median survival of patients with glioblastoma. The laboratory has also developed microchips and immunotherapy to further extend survival in this heretofore underserved population. These achievements were made possible by the dedication, commitment, and creativity of more than 300 trainees of the Hunterian Neurosurgical Laboratory. The laboratory demonstrates the beneficial influence of research experience as well its substantial impact on the field of biomedical research.

  17. Alexander Hamilton: Soldier-Statesmen of the Constitution. A Bicentennial Series No. 16.

    ERIC Educational Resources Information Center

    Army Center of Military History, Washington, DC.

    Alexander Hamilton was among the most intellectually gifted of the Founding Fathers and a brilliant political theorist, but he lacked practical political experience, and his major political contributions occurred only when his specific policies were adopted and carried forward by others with broader vision. This booklet on Hamilton is one in a…

  18. The Cannery Formation--Devonian to Early Permian arc-marginal deposits within the Alexander Terrane, Southeastern Alaska

    USGS Publications Warehouse

    Karl, Susan M.; Layer, Paul W.; Harris, Anita G.; Haeussler, Peter J.; Murchey, Benita L.

    2011-01-01

    cherts on both Admiralty and Kupreanof Islands contain radiolarians as young as Permian, the age of the Cannery Formation is herein extended to Late Devonian through early Permian, to include the early Permian rocks exposed in its type locality. The Cannery Formation is folded and faulted, and its stratigraphic thickness is unknown but inferred to be several hundred meters. The Cannery Formation represents an extended period of marine deposition in moderately deep water, with slow rates of deposition and limited clastic input during Devonian through Pennsylvanian time and increasing argillaceous, volcaniclastic, and bioclastic input during the Permian. The Cannery Formation comprises upper Paleozoic rocks in the Alexander terrane of southeastern Alaska. In the pre-Permian upper Paleozoic, the tectonic setting of the Alexander terrane consisted of two or more evolved oceanic arcs. The lower Permian section is represented by a distinctive suite of rocks in the Alexander terrane, which includes sedimentary and volcanic rocks containing early Permian fossils, metamorphosed rocks with early Permian cooling ages, and intrusive rocks with early Permian cooling ages, that form discrete northwest-trending belts. After restoration of 180 km of dextral displacement of the Chilkat-Chichagof block on the Chatham Strait Fault, these belts consist, from northeast to southwest, of (1) bedded chert, siliceous argillite, volcaniclastic turbidites, pillow basalt, and limestone of the Cannery Formation and the Porcupine Slate of Gilbert and others (1987); (2) greenschist-facies Paleozoic metasedimentary and metavolcanic rocks that have Permian cooling ages; (3) silty limestone and calcareous argillite interbedded with pillow basalt and volcaniclastic rocks of the Halleck Formation and the William Henry Bay area; and (4) intermediate-composition and syenitic plutons. These belts correspond to components of an accretionary complex, contemporary metamorphic rocks, forearc-basin deposits,

  19. Language and Communicative Development in Williams Syndrome

    ERIC Educational Resources Information Center

    Mervis, Carolyn B.; Becerra, Angela M.

    2007-01-01

    Williams syndrome, a genetic disorder caused by a microdeletion of approximately 25 genes on chromosome 7q11.23, is associated with mild to moderate intellectual disability or learning difficulties. Most individuals with Williams syndrome evidence a cognitive profile including relative strengths in verbal short-term memory and language, and…

  20. 75 FR 39910 - Prince William Sound Resource Advisory Committee; Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-13

    ... DEPARTMENT OF AGRICULTURE Forest Service Prince William Sound Resource Advisory Committee; Meeting AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Prince William Sound Resource..., Anchorage, Alaska 99503. Send written comments to Prince William Sound Resource Advisory Committee, c/o USDA...

  1. Social Cognition in Williams Syndrome: Face Tuning

    PubMed Central

    Pavlova, Marina A.; Heiz, Julie; Sokolov, Alexander N.; Barisnikov, Koviljka

    2016-01-01

    Many neurological, neurodevelopmental, neuropsychiatric, and psychosomatic disorders are characterized by impairments in visual social cognition, body language reading, and facial assessment of a social counterpart. Yet a wealth of research indicates that individuals with Williams syndrome exhibit remarkable concern for social stimuli and face fascination. Here individuals with Williams syndrome were presented with a set of Face-n-Food images composed of food ingredients and in different degree resembling a face (slightly bordering on the Giuseppe Arcimboldo style). The primary advantage of these images is that single components do not explicitly trigger face-specific processing, whereas in face images commonly used for investigating face perception (such as photographs or depictions), the mere occurrence of typical cues already implicates face presence. In a spontaneous recognition task, participants were shown a set of images in a predetermined order from the least to most resembling a face. Strikingly, individuals with Williams syndrome exhibited profound deficits in recognition of the Face-n-Food images as a face: they did not report seeing a face on the images, which typically developing controls effortlessly recognized as a face, and gave overall fewer face responses. This suggests atypical face tuning in Williams syndrome. The outcome is discussed in the light of a general pattern of social cognition in Williams syndrome and brain mechanisms underpinning face processing. PMID:27531986

  2. Social Cognition in Williams Syndrome: Face Tuning.

    PubMed

    Pavlova, Marina A; Heiz, Julie; Sokolov, Alexander N; Barisnikov, Koviljka

    2016-01-01

    Many neurological, neurodevelopmental, neuropsychiatric, and psychosomatic disorders are characterized by impairments in visual social cognition, body language reading, and facial assessment of a social counterpart. Yet a wealth of research indicates that individuals with Williams syndrome exhibit remarkable concern for social stimuli and face fascination. Here individuals with Williams syndrome were presented with a set of Face-n-Food images composed of food ingredients and in different degree resembling a face (slightly bordering on the Giuseppe Arcimboldo style). The primary advantage of these images is that single components do not explicitly trigger face-specific processing, whereas in face images commonly used for investigating face perception (such as photographs or depictions), the mere occurrence of typical cues already implicates face presence. In a spontaneous recognition task, participants were shown a set of images in a predetermined order from the least to most resembling a face. Strikingly, individuals with Williams syndrome exhibited profound deficits in recognition of the Face-n-Food images as a face: they did not report seeing a face on the images, which typically developing controls effortlessly recognized as a face, and gave overall fewer face responses. This suggests atypical face tuning in Williams syndrome. The outcome is discussed in the light of a general pattern of social cognition in Williams syndrome and brain mechanisms underpinning face processing.

  3. A new case of keratoconus associated with Williams-Beuren syndrome.

    PubMed

    Viana, Melissa Machado; Frasson, Maria; Leão, Letícia Lima; Stofanko, Martin; Gonçalves-Dornelas, Higgor; Cunha, Pricila da Silva; de Aguiar, Marcos José Burle

    2013-09-01

    Williams-Beuren syndrome is a multisystemic genetic disorder caused by a contiguous gene deletion at 7q11.23. Keratoconus is a complex disease and it is suspected to have a genetic origin, although the specific gene responsible for keratoconus has not been identified. Although there are several ocular features in Williams-Beuren syndrome, keratoconus is not regularly described as part of this syndrome. To report a new patient with keratoconus and Williams-Beuren syndrome. This is the third case of an association between Williams-Beuren syndrome and keratoconus. The authors believe that the Williams-Beuren syndrome chromosome region can be a possible target for further investigation as the genetic basis of keratoconus.

  4. 33 CFR 161.60 - Vessel Traffic Service Prince William Sound.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... William Sound. 161.60 Section 161.60 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND... Movement Reporting System Areas and Reporting Points § 161.60 Vessel Traffic Service Prince William Sound... Cape Hinchinbrook Light to Schooner Rock Light, comprising that portion of Prince William Sound between...

  5. 33 CFR 161.60 - Vessel Traffic Service Prince William Sound.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... William Sound. 161.60 Section 161.60 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND... Movement Reporting System Areas and Reporting Points § 161.60 Vessel Traffic Service Prince William Sound... Cape Hinchinbrook Light to Schooner Rock Light, comprising that portion of Prince William Sound between...

  6. 33 CFR 161.60 - Vessel Traffic Service Prince William Sound.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... William Sound. 161.60 Section 161.60 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND... Movement Reporting System Areas and Reporting Points § 161.60 Vessel Traffic Service Prince William Sound... Cape Hinchinbrook Light to Schooner Rock Light, comprising that portion of Prince William Sound between...

  7. 33 CFR 161.60 - Vessel Traffic Service Prince William Sound.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... William Sound. 161.60 Section 161.60 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND... Movement Reporting System Areas and Reporting Points § 161.60 Vessel Traffic Service Prince William Sound... Cape Hinchinbrook Light to Schooner Rock Light, comprising that portion of Prince William Sound between...

  8. 33 CFR 161.60 - Vessel Traffic Service Prince William Sound.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... William Sound. 161.60 Section 161.60 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND... Movement Reporting System Areas and Reporting Points § 161.60 Vessel Traffic Service Prince William Sound... Cape Hinchinbrook Light to Schooner Rock Light, comprising that portion of Prince William Sound between...

  9. Skin findings in Williams syndrome.

    PubMed

    Kozel, Beth A; Bayliss, Susan J; Berk, David R; Waxler, Jessica L; Knutsen, Russell H; Danback, Joshua R; Pober, Barbara R

    2014-09-01

    Previous examination in a small number of individuals with Williams syndrome (also referred to as Williams-Beuren syndrome) has shown subtly softer skin and reduced deposition of elastin, an elastic matrix protein important in tissue recoil. No quantitative information about skin elasticity in individuals with Williams syndrome is available; nor has there been a complete report of dermatologic findings in this population. To fill this knowledge gap, 94 patients with Williams syndrome aged 7-50 years were recruited as part of the skin and vascular elasticity (WS-SAVE) study. They underwent either a clinical dermatologic assessment by trained dermatologists (2010 WSA family meeting) or measurement of biomechanical properties of the skin with the DermaLab™ suction cup (2012 WSA family meeting). Clinical assessment confirmed that soft skin is common in this population (83%), as is premature graying of the hair (80% of those 20 years or older), while wrinkles (92%), and abnormal scarring (33%) were detected in larger than expected proportions. Biomechanical studies detected statistically significant differences in dP (the pressure required to lift the skin), dT (the time required to raise the skin through a prescribed gradient), VE (viscoelasticity), and E (Young's modulus) relative to matched controls. The RT (retraction time) also trended longer but was not significant. The biomechanical differences noted in these patients did not correlate with the presence of vascular defects also attributable to elastin insufficiency (vascular stiffness, hypertension, and arterial stenosis) suggesting the presence of tissue specific modifiers that modulate the impact of elastin insufficiency in each tissue. © 2014 Wiley Periodicals, Inc.

  10. Williams during EVA 36

    NASA Image and Video Library

    2016-08-19

    Extravehicular crewmember 1 (EV1) Jeff Williams pauses for a photo after installing a Hemispherical (Hemi) Reflector Cover on Pressurized Mating Adapter 2 (PMA-2) during Extravehicular Activity 36 (EVA 36).

  11. Walter C. Williams

    NASA Technical Reports Server (NTRS)

    1949-01-01

    Walter C. Williams arrived from the National Advisory Committee for Aeronautics, Langley Memorial Aeronautical Laboratory, Hampton, Virginia, on September 30, 1946, at the Muroc Army Air Field. He had been named the engineer-in-charge of the small group of five that came with him to the Rogers Dry Lakebed to take part in research flights of a joint NACA-Army Air Forces program involving the rocket-powered Bell XS-1. This established the first permanent National Advisory Committee for Aeronautics presence at the Mojave Desert site in California. This small group grew in numbers to 27 and received permanent status as the NACA Muroc Flight Test Unit from Hugh L. Dryden, NACA's Director of Research, on September 27, 1947. Walt was named Head of the Unit. On November 14, 1949, the Unit along with the 100 employees became the NACA High-Speed Flight Research Station with Walt Williams as Chief. Next came the move from the South Base site to the new headquarters, Bldg. 4800 on the north-west shore of the Rogers Dry lakebed on the Edwards Air Force Base complex. July 1, 1954 saw another name change to the NACA High-Speed Flight Station with Walt remaining the Chief to a complement of about 225 employees. Williams had received a Bachelor of Science Degree in aeronautical engineering from Louisiana State University, Baton Rouge, Louisiana, in 1939. After graduation, he was employed by the Glenn L. Martin Company of Baltimore, Maryland, and later that same year joined the staff of the NACA Langley Memorial Aeronautical Laboratory, where he worked as an engineer in the Flight Division. During the period from September 1946 to July 1954 Williams supervised the activities of several research projects. These included the first successful rocket-powered flight of the XS-1 made by Bell pilot Chalmers Goodlin on December 9, 1946; the record breaking flight of A.F. Captain Chuck Yeager on October 14, 1947, that exceeded the speed of sound; and the first flight of the jet

  12. Welfare effects of reduced milk production associated with Johne's disease on Johne's-positive versus Johne's-negative dairy operations.

    PubMed

    Losinger, Willard C

    2006-08-01

    An examination of the economic impacts of reduced milk production associated with Johne's disease on Johne's-positive and Johne's-negative dairy operations indicated that, if Johne's disease had not existed in US dairy cows in 1996, then the economic surplus of Johne's-negative operations would have been $600 million+/-$530 million lower, while the economic surplus of Johne's-positive operations would have been higher by $28 million+/-$79 million, which was not significantly different from zero. The data available for projecting changes in surplus were not sufficiently precise to allow an exact statement on whether Johne's-positive operations would have been better or worse off economically, in terms of the value received for producing more milk if they had not been affected by Johne's disease. The changes in producer surplus, based upon eliminating specific epidemiological risk factors for Johne's disease, were disaggregated between Johne's-positive dairy operations exposed to the risk factor and all other US dairy operations. Eliminating the risk factor of having any cows not born on the operation would have had a significant positive effect on the economic surplus of Johne's-positive operations that had any cows not born on the operation.

  13. Friendly Letters on the Correspondence of Helen Keller, Anne Sullivan, and Alexander Graham Bell.

    ERIC Educational Resources Information Center

    Blatt, Burton

    1985-01-01

    Excerpts from the letters between Alexander Graham Bell and Anne Sullivan and Helen Keller are given to illustrate the educational and personal growth of Helen Keller as well as the educational philosophy of Bell regarding the education of the deaf blind. (DB)

  14. 77 FR 76414 - William D. Ford Federal Direct Loan Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-28

    ... DEPARTMENT OF EDUCATION 34 CFR Part 685 RIN 1840-AC94 [Docket ID ED-2008-OPE-0009] William D. Ford... Loan (Perkins Loan) Program; the Federal Family Education Loan (FFEL) Program; and the William D. Ford.... Accordingly, 34 CFR part 685 is corrected as follows: PART 685--WILLIAM D. FORD FEDERAL DIRECT LOAN PROGRAM 0...

  15. Mental Health Problems in Adults with Williams Syndrome

    ERIC Educational Resources Information Center

    Stinton, Chris; Elison, Sarah; Howlin, Patricia

    2010-01-01

    Although many researchers have investigated emotional and behavioral difficulties in individuals with Williams syndrome, few have used standardized diagnostic assessments. We examined mental health problems in 92 adults with Williams syndrome using the Psychiatric Assessment Schedule for Adults with Developmental Disabilities--PAS-ADD (Moss,…

  16. William Burke Critchfield

    Treesearch

    Connie Millar

    1990-01-01

    William B. Critchfield died July 11, 1989. He left a legacy unparalleled in forest genetics. Bill made major contributions to understanding genetic variation, hybridization, growth and development, biogeography, paleobotany, systematics, and taxonomy of forest trees, especially pines. In each of these fields, Bill's pioneering work earned him the position of world...

  17. Mission, Science, and Race in South Africa; AW Roberts of Lovedale 1883-1938

    NASA Astrophysics Data System (ADS)

    Glass, I.S.

    2016-02-01

    Book Review: Biography of Alexander William Roberts. Noted educator, variable star observer and politician who represented South African "natives" in the parliament of the Union of South Africa at a time when they had no other representation.

  18. 34 CFR 685.100 - The William D. Ford Federal Direct Loan Program.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false The William D. Ford Federal Direct Loan Program. 685...) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION WILLIAM D. FORD FEDERAL DIRECT LOAN PROGRAM Purpose and Scope § 685.100 The William D. Ford Federal Direct Loan Program. (a) Under the William D. Ford...

  19. Congenital heart defects in Williams syndrome.

    PubMed

    Yuan, Shi-Min

    2017-01-01

    Yuan SM. Congenital heart defects in Williams syndrome. Turk J Pediatr 2017; 59: 225-232. Williams syndrome (WS), also known as Williams-Beuren syndrome, is a rare genetic disorder involving multiple systems including the circulatory system. However, the etiologies of the associated congenital heart defects in WS patients have not been sufficiently elucidated and represent therapeutic challenges. The typical congenital heart defects in WS were supravalvar aortic stenosis, pulmonary stenosis (both valvular and peripheral), aortic coarctation and mitral valvar prolapse. The atypical cardiovascular anomalies include tetralogy of Fallot, atrial septal defects, aortic and mitral valvular insufficiencies, bicuspid aortic valves, ventricular septal defects, total anomalous pulmonary venous return, double chambered right ventricle, Ebstein anomaly and arterial anomalies. Deletion of the elastin gene on chromosome 7q11.23 leads to deficiency or abnormal deposition of elastin during cardiovascular development, thereby leading to widespread cardiovascular abnormalities in WS. In this article, the distribution, treatment and surgical outcomes of typical and atypical cardiac defects in WS are discussed.

  20. John Tyndall and the Early History of Diamagnetism.

    PubMed

    Jackson, Roland

    2015-01-01

    John Tyndall, Irish-born natural philosopher, completed his PhD at the University of Marburg in 1850 while starting his first substantial period of research into the phenomenon of diamagnetism. This paper provides a detailed analysis and evaluation of his contribution to the understanding of magnetism and of the impact of this work on establishing his own career and reputation; it was instrumental in his election as a Fellow of the Royal Society in 1852 and as Professor of Natural Philosophy at the Royal Institution in 1853. Tyndall's interactions and relationships with Michael Faraday, William Thomson, Julius Plücker and others are explored, alongside his contributions to experimental practice and to emerging theory. Tyndall's approach, challenging Faraday's developing field theory with a model of diamagnetic polarity and the effect of magnetic forces acting in couples, was based on his belief in the importance of underlying molecular structure, an idea which suffused his later work, for example in relation to the study of glaciers and to the interaction of substances with radiant heat.

  1. John Tyndall and the Early History of Diamagnetism

    PubMed Central

    Jackson, Roland

    2015-01-01

    Summary John Tyndall, Irish-born natural philosopher, completed his PhD at the University of Marburg in 1850 while starting his first substantial period of research into the phenomenon of diamagnetism. This paper provides a detailed analysis and evaluation of his contribution to the understanding of magnetism and of the impact of this work on establishing his own career and reputation; it was instrumental in his election as a Fellow of the Royal Society in 1852 and as Professor of Natural Philosophy at the Royal Institution in 1853. Tyndall's interactions and relationships with Michael Faraday, William Thomson, Julius Plücker and others are explored, alongside his contributions to experimental practice and to emerging theory. Tyndall's approach, challenging Faraday's developing field theory with a model of diamagnetic polarity and the effect of magnetic forces acting in couples, was based on his belief in the importance of underlying molecular structure, an idea which suffused his later work, for example in relation to the study of glaciers and to the interaction of substances with radiant heat. PMID:26221835

  2. Recent paleoseismicity record in Prince William Sound, Alaska, USA

    NASA Astrophysics Data System (ADS)

    Kuehl, Steven A.; Miller, Eric J.; Marshall, Nicole R.; Dellapenna, Timothy M.

    2017-12-01

    Sedimentological and geochemical investigation of sediment cores collected in the deep (>400 m) central basin of Prince William Sound, along with geochemical fingerprinting of sediment source areas, are used to identify earthquake-generated sediment gravity flows. Prince William Sound receives sediment from two distinct sources: from offshore (primarily Copper River) through Hinchinbrook Inlet, and from sources within the Sound (primarily Columbia Glacier). These sources are found to have diagnostic elemental ratios indicative of provenance; Copper River Basin sediments were significantly higher in Sr/Pb and Cu/Pb, whereas Prince William Sound sediments were significantly higher in K/Ca and Rb/Sr. Within the past century, sediment gravity flows deposited within the deep central channel of Prince William Sound have robust geochemical (provenance) signatures that can be correlated with known moderate to large earthquakes in the region. Given the thick Holocene sequence in the Sound ( 200 m) and correspondingly high sedimentation rates (>1 cm year-1), this relationship suggests that sediments within the central basin of Prince William Sound may contain an extraordinary high-resolution record of paleoseismicity in the region.

  3. Rejoinder to Craig A. Cunningham, David Granger, Jane Fowler Morse, Barbara Stengel, and Terri Wilson, "Dewey, Women, and Weirdoes"

    ERIC Educational Resources Information Center

    Fitzgerald, Terry

    2010-01-01

    It is good to see Cunningham et al. including F. Matthias Alexander in their list of positive influences in John Dewey's life. However, I believe Cunningham's essay, "Shared explorations of body-mind: the reciprocal influences of Dewey and F.M. Alexander", falls short in its acknowledgement of Alexander and in one important aspect is incorrect. In…

  4. Alexander von Humboldt's perceptions of colonial Spanish America.

    PubMed

    Rebok, Sandra

    2009-01-01

    This study presents an in-depth analysis of Alexander von Humboldt's descriptions and critical comments on the colonial society of the different regions he visited during his well-known expedition through the Americas (1799-1804). The criticisms of colonialism that he expressed, reflecting his personal convictions, have already been the focal point of many studies, but Humboldt also was able to offer a more differentiated assessment through comparisons of regional and local traditions and developments. This essay focuses on his personal diaries, which offer many interesting comments on colonial societies. These considerations and impressions made during the expedition are of particular scholarly value since they were not subject to censorship of any kind.

  5. Emotional Responsivity in Young Children with Williams Syndrome

    ERIC Educational Resources Information Center

    Fidler, Debbie J.; Hepburn, Susan L.; Most, David E.; Philofsky, Amy; Rogers, Sally J.

    2007-01-01

    The hypothesis that young children with Williams syndrome show higher rates of emotional responsivity relative to other children with developmental disabilities was explored. Performance of 23 young children with Williams syndrome and 30 MA-matched children with developmental disabilities of nonspecific etiologies was compared on an adaptation of…

  6. Parent insights into atypicalities of social approach behaviour in Williams syndrome.

    PubMed

    Lough, E; Rodgers, J; Janes, E; Little, K; Riby, D M

    2016-11-01

    Individuals with Williams syndrome have been reported to show high levels of social interest and a desire to interact with others irrespective of their familiarity. This high social motivation, when combined with reduced intellectual capacity and a profile of atypical social behaviour, is important in terms of social vulnerability of individuals with the disorder. Therefore, social approach to unfamiliar people and the role of this behaviour within the Williams syndrome (WS) social phenotype warrant further research to inform social skills' intervention design. The current study used parent interviews (n = 21) to probe aspects of social behaviour and interactions with strangers, as well as the impact of such behaviour on the family. Using thematic analysis, it was possible to explore themes that emerged from the interviews, offering qualitatively rich insight into the variability of social approach behaviour in WS. Thematic analysis confirmed a significant desire to interact with strangers as well as a lack of awareness of appropriate social boundaries. However, parental reports about their child's social approach behaviour varied considerably. The within-syndrome variability of the sample was emphasised in parental reports of their child's personality characteristics (e.g. levels of impulsiveness), as well as the level of parental supervision employed. These in-depth parent insights can help target the needs of individuals with WS and emphasise that an individual approach to intervention will be essential because of the heterogeneity of the WS social profile. © 2016 MENCAP and International Association of the Scientific Study of Intellectual and Developmental Disabilities and John Wiley & Sons Ltd.

  7. The Election of 1800: Alexander Hamilton and the Death of the Federalist Party.

    ERIC Educational Resources Information Center

    Holbrook-DeFeo, Gary

    1993-01-01

    Describes the significance of the election of 1800 in the development of political parties in the United States. Contends that Alexander Hamilton's view of the United States Constitution was dangerous for the new nation and led to a permanent split in the Federalist Party. Includes a resource bibliography for teachers wishing to incorporate this…

  8. Infantile ictal apneas in a child with williams-beuren syndrome.

    PubMed

    Myers, Kenneth A; McLeod, D Ross; Bello-Espinosa, Luis

    2013-02-01

    Williams-Beuren syndrome is a genetic disorder rarely associated with seizures. The few described cases of Williams-Beuren syndrome and epilepsy have primarily involved infantile spasms and deletions extending beyond the common deletion region for this disorder. We present the case of a 5-week-old child with ictal apneas and typical Williams-Beuren syndrome deletion. Diagnosis was challenging, because the child had cardiac, respiratory, and gastrointestinal abnormalities typically associated with Williams-Beuren syndrome, which are also associated with cyanotic episodes. The results of interictal electroencephalography were normal, illustrating that prolonged electroencephalography is often essential in evaluation of suspected ictal apneas. Seizure freedom was achieved with carbamazepine. Sudden death is seen in Williams-Beuren syndrome, and this case raises the question whether some of these cases may be related to ictal apneas and could potentially be preventable with appropriate pharmaceutical intervention. Copyright © 2013 Elsevier Inc. All rights reserved.

  9. Alexander of Macedon, the greatest warrior of all times: did he have seizures?

    PubMed

    Hughes, John R

    2004-10-01

    Alexander the Great (356-323 BC) was likely "the most incomparable general the world has ever seen." His name is often listed among the famous individuals in history who have had seizures. Examination of his illnesses reveals that in 333 BC he entered Tarsus, hot and exhausted, and plunged himself into the River Cydnus, ice-cold from melting mountain snows. His cramps were so severe that he was rescued half-conscious and ashen white, and quickly developed acute pneumonia. Only one doctor dared give him a medication, known for producing powerful and immediate effects. Immediately after drinking this medicine "he lost his speech and falling into a swoon, he had scarcely any sense or pulse left" (Plutarch, ad 75). His reactions were the direct effect of the medication, and this and only this phrase represents the "evidence" for epilepsy. None of his other illnesses involved seizures. Clearly, Alexander the Great did not have epilepsy and his name should be removed from the list of famous individuals who have had seizures.

  10. Apprentice Class Graduates

    NASA Image and Video Library

    1960-05-14

    Apprentice Class Graduates: 32 Apprentice Greaduates: Ivan E. Albertson, Colossie N. Batts, Billy W. Beasley, John H. Belveal, Ernest R. Dunnigan, Durwood W. Davis, Charles E. Drummond, John R.Ellingsworth, Jr., Hugh D. Fitzgerald, Ernest A. Gurganus, Joseph R. Guy, William C. Henley,Jr., Richard N. Hill, Hiram R. Hogge, Jr., James D. Holt, James L. Hudgins, Robert F. Macklin, Roy W. Mason, Clyde J. May,Roger N. Messier, William C. Moughon, William S. Pillow, Wayne R. Posey, Mark E. Price, John W. Schwartz, Herbert F. Shackleford, John W. Simpson,John B. Slight, Cecil W. Stephens, Richard K. Stoops, John W. Sundy, Dave, E. Williams.

  11. Celiac disease in patients with Williams-Beuren syndrome.

    PubMed

    Mıhçı, Ercan; Nur, Banu Güzel; Berker-Karaüzüm, Sibel; Yılmaz, Aygen; Artan, Reha

    2015-01-01

    Celiac disease is an autoimmune, gastrointestinal disorder characterized by intolerance to the dietary grain protein gluten. An increased prevalence of celiac disease has been reported in Down syndrome and Turner syndrome, but there has been only few previous reports with respect to the association of celiac disease in Williams-Beuren syndrome. The aim of this study was to evaluate the frequency of celiac disease in our 24 Williams-Beuren syndrome patients. Gastrointestinal problems and celiac disease symptoms of patients were noted. All patients were analyzed by the titer of tissue transglutaminases IgA and IgG. HLA genotyping and intestinal biopsy was performed to the patients with positive serology. We also performed gluten free diet in the presence of compatible symptoms, serology, HLA genotyping and intestinal biopsy. In our study, two patients had positive tTG antibodies, but only one had positive biopsy finding for celiac disease. The frequency of celiac disease in patients with Williams-Beuren syndrome was estimated as 1/24 (4.1%). Though the number of participants in this study was limited, the results show that the frequency of celiac disease is higher in Williams-Beuren syndrome compared to the general population. We suggest that a high suspicion and testing for celiac disease should be recommended at certain intervals in all cases with Williams-Beuren syndrome to detect the cause of growth retardation and gastrointestinal problems.

  12. The circulation of Prince William Sound

    NASA Technical Reports Server (NTRS)

    Muench, R. D. (Principal Investigator)

    1973-01-01

    The author has identified the following significant results. Results suggest that sediment-laden plumes of fresh water from rivers may be useful tracers, due to their high visibility, of surface water motion. The two useable images obtained to date corroborate that westerly flow was occurring in the Gulf of Alaska just south of Prince William Sound, and that an inflow into Prince William Sound was occurring concurrently with flood tides on both occasions. River plumes are useful tracers, but poor weather conditions somewhat limit the use of satellite imagery.

  13. The Williams Review

    ERIC Educational Resources Information Center

    Knight, Rupert

    2009-01-01

    The publication in June of Sir Peter Williams' review of mathematics teaching in early years' settings and primary schools came at a time when the thoughts of many teachers were turning towards a well-earned summer break. However, the report has attracted much attention and promises a fundamental shake-up of attitudes and approaches to the…

  14. Myelin changes in Alexander disease.

    PubMed

    Gómez-Pinedo, U; Duran-Moreno, M; Sirerol-Piquer, S; Matias-Guiu, J

    2017-03-22

    Alexander disease (AxD) is a type of leukodystrophy. Its pathological basis, along with myelin loss, is the appearance of Rosenthal bodies, which are cytoplasmic inclusions in astrocytes. Mutations in the gene coding for GFAP have been identified as a genetic basis for AxD. However, the mechanism by which these variants produce the disease is not understood. The most widespread hypothesis is that AxD develops when a gain of function mutation causes an increase in GFAP. However, this mechanism does not explain myelin loss, given that experimental models in which GFAP expression is normal or mutated do not exhibit myelin disorders. This review analyses other possibilities that may explain this alteration, such as epigenetic or inflammatory alterations, presence of NG2 (+) - GFAP (+) cells, or post-translational modifications in GFAP that are unrelated to increased expression. The different hypotheses analysed here may explain the myelin alteration affecting these patients, and multiple mechanisms may coexist. These theories raise the possibility of designing therapies based on these mechanisms. Copyright © 2017 Sociedad Española de Neurología. Publicado por Elsevier España, S.L.U. All rights reserved.

  15. Williams Syndrome and 15q Duplication: Coincidence versus Association.

    PubMed

    Khokhar, Aditi; Agarwal, Swashti; Perez-Colon, Sheila

    2017-01-01

    Williams syndrome is a multisystem disorder caused by contiguous gene deletion in 7q11.23, commonly associated with distinctive facial features, supravalvular aortic stenosis, short stature, idiopathic hypercalcemia, developmental delay, joint laxity, and a friendly personality. The clinical features of 15q11q13 duplication syndrome include autism, mental retardation, ataxia, seizures, developmental delay, and behavioral problems. We report a rare case of a girl with genetically confirmed Williams syndrome and coexisting 15q duplication syndrome. The patient underwent treatment for central precocious puberty and later presented with primary amenorrhea. The karyotype revealed 47,XX,+mar. FISH analysis for the marker chromosome showed partial trisomy/tetrasomy for proximal chromosome 15q (15p13q13). FISH using an ELN -specific probe demonstrated a deletion in the Williams syndrome critical region in 7q11.23. To our knowledge, a coexistence of Williams syndrome and 15q duplication syndrome has not been reported in the literature. Our patient had early pubertal development, which has been described in some patients with Williams syndrome. However, years later after discontinuing gonadotropin-releasing hormone analogue treatment, she developed primary amenorrhea.

  16. Two Project Methods: Preliminary Observations on the Similarities and Differences between William Heard Kilpatrick's Project Method and John Dewey's Problem-Solving Method

    ERIC Educational Resources Information Center

    Sutinen, Ari

    2013-01-01

    The project method became a famous teaching method when William Heard Kilpatrick published his article "Project Method" in 1918. The key idea in Kilpatrick's project method is to try to explain how pupils learn things when they work in projects toward different common objects. The same idea of pupils learning by work or action in an…

  17. 76 FR 44893 - Prince William Sound Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-27

    ... DEPARTMENT OF AGRICULTURE Forest Service Prince William Sound Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Prince William Sound Resource Advisory... District, 145 Forest Station Road, Girdwood, AK; Prince Willam Sound Community College, 303 Lowe Street...

  18. 33 CFR 165.1704 - Prince William Sound, Alaska-regulated navigation area.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false Prince William Sound, Alaska... District § 165.1704 Prince William Sound, Alaska-regulated navigation area. (a) The following is a... Hinchinbrook Light to Schooner Rock Light, comprising that portion of Prince William Sound between 146°30′ W...

  19. 33 CFR 165.1704 - Prince William Sound, Alaska-regulated navigation area.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Prince William Sound, Alaska... District § 165.1704 Prince William Sound, Alaska-regulated navigation area. (a) The following is a... Hinchinbrook Light to Schooner Rock Light, comprising that portion of Prince William Sound between 146°30′ W...

  20. 33 CFR 165.1704 - Prince William Sound, Alaska-regulated navigation area.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 2 2014-07-01 2014-07-01 false Prince William Sound, Alaska... District § 165.1704 Prince William Sound, Alaska-regulated navigation area. (a) The following is a... Hinchinbrook Light to Schooner Rock Light, comprising that portion of Prince William Sound between 146°30′ W...

  1. 33 CFR 165.1704 - Prince William Sound, Alaska-regulated navigation area.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Prince William Sound, Alaska... District § 165.1704 Prince William Sound, Alaska-regulated navigation area. (a) The following is a... Hinchinbrook Light to Schooner Rock Light, comprising that portion of Prince William Sound between 146°30′ W...

  2. 33 CFR 165.1704 - Prince William Sound, Alaska-regulated navigation area.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Prince William Sound, Alaska... District § 165.1704 Prince William Sound, Alaska-regulated navigation area. (a) The following is a... Hinchinbrook Light to Schooner Rock Light, comprising that portion of Prince William Sound between 146°30′ W...

  3. John Collins Warren: Master educator and pioneer surgeon of ether fame.

    PubMed

    Toledo, Alexander Horacio

    2006-01-01

    John Collins Warren (1778-1856) represented the apex of surgery and medicine of the first half of nineteenth century Boston. Educated at Harvard College where he obtained a Bachelor of Arts in 1797, he contemplated the idea of a business career prior to setting sail for a traditional medical education at Europe's finest universities. From 1799 to 1802, he attended prestigious medical and surgical lectures in London, Edinburgh, and Paris. Warren received an honorary MD from Scotland's St. Andrews University in 1802. He then returned to Boston and joined his father's practice. In 1815, he followed his accomplished father as the Hersey Professor of Anatomy and Surgery at Harvard Medical School. He held this position with great distinction until 1847 when he retired as professor emeritus. From 1816 to 1819 he served as Harvard Medical School dean and received an honorary medical degree at the end of his term.John Collins Warren had numerous surgical accomplishments during his illustrious career. Clinically, he was active and varied in his practice, operating on strangulated hernias, tumors, and cataracts, in addition to performing vascular surgery and amputations. He published many articles and books of widespread circulation. Professor Warren also performed the first reported case of ether anesthesia administered by William T. Morton on October 16, 1846. Outside the operating theatre, Doctor Warren and his colleagues were revered for founding the Massachusetts General Hospital in 1821, and years before, in 1812, Warren and his associates established the New England Journal of Medicine and Surgery. In light of his varied contributions, John Collins Warren is remembered as a dedicated and innovative surgeon, as well as a committed medical educator, able administrator and effective leader.

  4. Mailability v. the Crusader: Williams v. O'Brien.

    ERIC Educational Resources Information Center

    Simmons, Charles E.

    The issues of prior restraint and press censorship are examined in this paper, which focuses on the 1970 Williams v. O'Brien court case. The paper discusses the litigation, in which Robert F. Williams, as an American citizen living in Peking, China, sued the United States Postmaster General over the banning of the May 1967 issue of "The…

  5. Alexander Thomas Augusta--physician, teacher and human rights activist.

    PubMed

    Butts, Heather M

    2005-01-01

    Commissioned surgeon of colored volunteers, April 4, 1863, with the rank of Major. Commissioned regimental surgeon on the 7th Regiment of U.S. Colored Troops, October 2, 1863. Brevet Lieutenant Colonel of Volunteers, March 13, 1865, for faithful and meritorious services--mustered out October 13, 1866. So reads the tombstone at Arlington National Cemetery of Alexander Thomas Augusta, the first black surgeon commissioned in the Union Army during the Civil War and the first black officer-rank soldier to be buried at Arlington Cemetery. He was also instrumental in founding the institutions that later became the hospital and medical college of Howard University and the National Medical Association.

  6. Draft Genome Sequence of the Mycobacterium tuberculosis Complex Pathogen M. mungi, Identified in a Banded Mongoose (Mungos mungo) in Northern Botswana.

    PubMed

    Alexander, Kathleen A; Larsen, Michelle H; Robbe-Austerman, Suelee; Stuber, Tod P; Camp, Patrick M

    2016-07-28

    Mycobacterium mungi, a Mycobacterium tuberculosis complex pathogen, has emerged in banded mongoose in northern Botswana and Northwest Zimbabwe. The pathogen is transmitted through infected secretions used in olfactory communication behavior (K. A. Alexander, C. E. Sanderson, M. H. Larsen, S. Robbe-Austerman, M. C. Williams, and M. V. Palmer, mBio 7(3):e00281-16, 2016, http://dx.doi.org/10.1128/mBio.00281-16). We announce here the draft genome sequence of this emerging pathogen. Copyright © 2016 Alexander et al.

  7. Hemizygosity at the elastin locus and clinical features of Williams syndrome

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Morimoto, Y; Kuwano, A.; Kuwajima, K.

    1994-09-01

    Williams syndrome is a recognizable syndrome characterized by distinctive facial appearance, gregarious personality, mental retardation, congenital heart defect, particularly supravalvular aortic stenosis (SVAS), and joint limitation. SVAS is an autosomal vascular disorder and the elastin gene was disrupted in patients with SVAS. Ewat et al. reported that hemizygosity at the elastin locus was detected in four familial and five sporadic cases of Williams syndrome. However, three patients did not have SVAS. We reconfirmed hemizygosity at the elastin locus in five patients with typical clinical features of Williams syndrome. Hemizygosity was detected in four cases with SVAS. However, one patient withmore » distinctive facial appearance and typical Williams syndrome personality had two alleles of the elastin gene, but he did not have the congenital heart anomaly. Williams syndrome is thought to be a contiguous gene disorder. Thus, our data suggest that the elastin gene is responsible for the vascular defect in patients with Williams syndrome, and flanking genes are responsible for characteristic facial appearance and personality.« less

  8. Prince William Forest Park American Beech , Approximately one mile ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Prince William Forest Park American Beech , Approximately one mile from visitor’s center, south bank of the south fork of Quantico Creek, about 75 yards upstream from its confluence with Quantico Creek, Near Birch Bluff Trail, Triangle, Prince William County, VA

  9. 77 FR 19301 - Prince William Sound Regional Citizens' Advisory Council Charter Renewal

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-30

    ... DEPARTMENT OF HOMELAND SECURITY Coast Guard [USCG-2012-0099] Prince William Sound Regional... Prince William Sound Regional Citizens' Advisory Council (PWSRCAC) as an alternative voluntary advisory group for Prince William Sound, Alaska. This certification allows the PWSRCAC to monitor the activities...

  10. Interaction with William Carnall

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Judd, Brian R.

    2005-02-15

    A personal account is given of interaction with William T. Carnall during the period 1977-1988, when I made regular visits to the Argonne National Laboratory to discuss the theoretical background to the spectroscopic work he was carrying out on the lanthanides and actinides.

  11. Williams Exercises in Zvezda

    NASA Image and Video Library

    2007-01-13

    ISS014-E-11786 (13 Jan. 2007) --- Surrounded by hardware, astronaut Sunita L. Williams, Expedition 14 flight engineer, equipped with a bungee harness, exercises on the Treadmill Vibration Isolation System (TVIS) (out of frame) in the Zvezda Service Module of the International Space Station.

  12. Williams Exercises in Zvezda

    NASA Image and Video Library

    2007-01-13

    ISS014-E-11784 (13 Jan. 2007) --- Surrounded by hardware, astronaut Sunita L. Williams, Expedition 14 flight engineer, equipped with a bungee harness, exercises on the Treadmill Vibration Isolation System (TVIS) (out of frame) in the Zvezda Service Module of the International Space Station.

  13. Global and local music perception in children with Williams syndrome.

    PubMed

    Deruelle, Christine; Schön, Daniele; Rondan, Cécilie; Mancini, Josette

    2005-04-25

    Musical processing can be decomposed into the appreciation of global and local elements. This global/local dissociation was investigated with the processing of contour-violated and interval-violated melodies. Performance of a group of 16 children with Williams syndrome and a group of 16 control children were compared in a same-different task. Control participants were more accurate in detecting differences in the contour-violated than in the interval-violated condition while Williams syndrome individuals performed equally well in both conditions. This finding suggests that global precedence may occur at an early perceptual stage in normally developing children. In contrast, no such global precedence is observed in the Williams syndrome population. These data are discussed in the context of atypical cognitive profiles of individuals with Williams syndrome.

  14. Behavioral and Emotional Disturbance in Individuals with Williams Syndrome.

    ERIC Educational Resources Information Center

    Einfeld, Stewart L.; Tonge, Bruce J.; Florio, Tony

    1997-01-01

    Comparison of behavioral and emotional disturbance in 70 children and adolescents with Williams Syndrome (characterized by mental retardation and short stature) and a control group, found Williams Syndrome subjects were more likely to be diagnosed with a psychiatric disorder characterized by anxiety, hyperactivity, preoccupations, and…

  15. The clinical spectrum of late-onset Alexander disease: a systematic literature review.

    PubMed

    Balbi, Pietro; Salvini, Silvana; Fundarò, Cira; Frazzitta, Giuseppe; Maestri, Roberto; Mosah, Dibo; Uggetti, Carla; Sechi, GianPietro

    2010-12-01

    Following the discovery of glial fibrillary acidic protein (GFAP) mutations as the causative factor of Alexander disease (AxD), new case reports have recently increased, prompting a more detailed comprehension of the clinical features of the three disease subtypes (infantile, juvenile and adult). While the clinical pattern of the infantile form has been substantially confirmed, the late-onset subtypes (i.e., juvenile and adult), once considered rare manifestations of AxD, have displayed a wider clinical spectrum. Our aim was to evaluate the clinical phenotype of the adult and juvenile forms by reviewing the previously reported cases. Data were collected from previously published reports on 112 subjects affected by neuropathologically or genetically proven adult and juvenile Alexander disease. Although the late-onset forms of AxD show a wide clinical variability, a common pattern emerges from comparing previously reported cases, characterized by pseudo-bulbar signs, ataxia, and spasticity, associated with atrophy of the medulla and upper cervical cord on neuroimaging. Late-onset AxD cases can no longer be considered as rare manifestations of the disease. The clinical pattern usually reflects the topographic localization of the lesions, with adult cases displaying a predominant infratentorial localization of the lesions. Juvenile cases show clinical and radiological features which are intermediate between adult and infantile forms.

  16. 2. WILLIAM ELLIOT CABIN AND OUTBULIDING, CABIN WEST REAR AND ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. WILLIAM ELLIOT CABIN AND OUTBULIDING, CABIN WEST REAR AND NORTH SIDES, OUTBULIDING WEST FRONT AND NORTH SIDE - Liberty Historic District, William Elliot Cabin, Route 2, Cle Elum, Liberty, Kittitas County, WA

  17. 1. WILLIAM ELLIOT CABIN AND OUTBUILDING, CABIN EAST FRONT AND ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. WILLIAM ELLIOT CABIN AND OUTBUILDING, CABIN EAST FRONT AND SOUTH SIDE, OUTBUILDING EAST REAR AND SOUTH SIDES - Liberty Historic District, William Elliot Cabin, Route 2, Cle Elum, Liberty, Kittitas County, WA

  18. After the Wall: The Remaking of East German Education.

    ERIC Educational Resources Information Center

    Costello, Kevin

    1992-01-01

    Huge changes are taking place throughout the former East German society. Comments from students, teachers, and administrators at Potsdam's William and Alexander Humboldt High School, just outside Berlin, highlight the difficult tasks involved in reforming an impoverished and repressive school system. (MLF)

  19. Intracranial arteries in individuals with the elastin gene hemideletion of Williams syndrome.

    PubMed

    Wint, D P; Butman, J A; Masdeu, J C; Meyer-Lindenberg, A; Mervis, C B; Sarpal, D; Morris, C A; Berman, K F

    2014-01-01

    Williams syndrome, a rare genetic disorder with a striking neurobehavioral profile characterized by extreme sociability and impaired visuospatial construction abilities, is caused by a hemideletion that includes the elastin gene, resulting in frequent supravavular aortic stenosis and other stenotic arterial lesions. Strokes have been reported in Williams syndrome. Although the extracranial carotid artery has been studied in a sample of patients with Williams syndrome, proximal intracranial arteries have not. Using MRA, we studied the intracranial vessels in 27 participants: 14 patients with Williams syndrome (age range, 18-44 years; mean age, 27.3 ± 9.1; 43% women) and 13 healthy control participants with similar age and sex distribution (age range, 22-52 years; mean age, 33.4 ± 7.6; 46% women). All participants with Williams syndrome had hemideletions of the elastin gene. Blinded to group allocation or to any other clinical data, a neuroradiologist determined the presence of intracranial vascular changes in the 2 groups. The Williams syndrome group and the healthy control group had similar patency of the proximal intracranial arteries, including the internal carotid and vertebral arteries; basilar artery; and stem and proximal branches of the anterior cerebral artery, MCA, and posterior cerebral arteries. The postcommunicating segment of the anterior cerebral artery was longer in the Williams syndrome group. Despite the elastin haploinsufficiency, the proximal intracranial arteries in Williams syndrome preserve normal patency.

  20. [Association between Williams syndrome and adrenal insufficiency].

    PubMed

    Rchachi, Meryem; Larwanou, Maazou Mahamane; El Ouahabi, Hanan; Ajdi, Farida

    2017-01-01

    Williams syndrome is a developmental disorder including dysmorphia, cardiovascular malformations and a specific neuropsychological profile together with other associated disorders. We report the case of a 17-year old girl, born of a non-inbred marriage, with Williams syndrome discovered during an assessment of degree of failure to thrive. Its association with primary adrenal insufficiency makes it unique. Diagnosis is confirmed by cytogenetic and molecular analysis. Its management consists of the implementation of treatment for adrenal insufficiency associated with a clinico-biological monitoring.

  1. White matter integrity deficits in prefrontal-amygdala pathways in Williams syndrome.

    PubMed

    Avery, Suzanne N; Thornton-Wells, Tricia A; Anderson, Adam W; Blackford, Jennifer Urbano

    2012-01-16

    Williams syndrome is a neurodevelopmental disorder associated with significant non-social fears. Consistent with this elevated non-social fear, individuals with Williams syndrome have an abnormally elevated amygdala response when viewing threatening non-social stimuli. In typically-developing individuals, amygdala activity is inhibited through dense, reciprocal white matter connections with the prefrontal cortex. Neuroimaging studies suggest a functional uncoupling of normal prefrontal-amygdala inhibition in individuals with Williams syndrome, which might underlie both the extreme amygdala activity and non-social fears. This functional uncoupling might be caused by structural deficits in underlying white matter pathways; however, prefrontal-amygdala white matter deficits have yet to be explored in Williams syndrome. We used diffusion tensor imaging to investigate prefrontal-amygdala white matter integrity differences in individuals with Williams syndrome and typically-developing controls with high levels of non-social fear. White matter pathways between the amygdala and several prefrontal regions were isolated using probabilistic tractography. Within each pathway, we tested for between-group differences in three measures of white matter integrity: fractional anisotropy (FA), radial diffusivity (RD), and parallel diffusivity (λ(1)). Individuals with Williams syndrome had lower FA, compared to controls, in several of the prefrontal-amygdala pathways investigated, indicating a reduction in white matter integrity. Lower FA in Williams syndrome was explained by significantly higher RD, with no differences in λ(1), suggestive of lower fiber density or axon myelination in prefrontal-amygdala pathways. These results suggest that deficits in the structural integrity of prefrontal-amygdala white matter pathways might underlie the increased amygdala activity and extreme non-social fears observed in Williams syndrome. Copyright © 2011 Elsevier Inc. All rights reserved.

  2. 76 FR 2902 - Williams, Barry Lawson; Notice of Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-18

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. ID-2449-005] Williams, Barry Lawson; Notice of Filing January 10, 2011. Take notice that on January 10, 2011, Barry Lawson Williams... [email protected] , or call (866) 208-3676 (toll free). For TTY, call (202) 502-8659. Comment Date...

  3. 75 FR 62530 - Williams, Barry Lawson; Notice of Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-12

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. ID-6409-000] Williams, Barry Lawson; Notice of Filing October 4, 2010. Take notice that on September 24, 2010, Barry Lawson Williams..., please e-mail [email protected] , or call (866) 208-3676 (toll free). For TTY, call (202) 502...

  4. Genetics Home Reference: Williams syndrome

    MedlinePlus

    ... Berman KF. Neural correlates of genetically abnormal social cognition in Williams syndrome. Nat Neurosci. 2005 Aug;8( ... syndrome: a unique window to genetic influences on cognition and behaviour. Nat Rev Neurosci. 2006 May;7( ...

  5. SLEEP - Williams wearing sleep net

    NASA Image and Video Library

    1998-05-12

    STS090-377-011 (17 APRIL-3 MAY 1998) --- Astronaut Dafydd R. (Dave) Williams, mission specialist representing the Canadian Space Agency (CSA), accomplishes more than one purpose when he sleeps in this bunk aboard the Earth-orbiting Space Shuttle Columbia. Conducting a Neurolab sleep experiment, Williams wears equipment which includes a sleep net (mesh cap that monitors and records brain waves); a Respiratory Inductance Plethysmograph (RIP) suit for monitoring respiration; and an activity monitor -- a device (out of view) worn on the wrist to detect and record body movement. Data on brain waves, eye movements, respiration, heart rate, and oxygen concentration are routed to a portable data recorder. The entire system has capabilities similar to a fully equipped sleep laboratory on Earth. The sleeping bag is conventional Shuttle ware and not part of the experiment.

  6. View of Mission Street facing south west. Williams Building is ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View of Mission Street facing south west. Williams Building is at left background, Aron (Mercantile) Building is at right background. Parking lot is in left foreground - Williams Building, 693 Mission Street, San Francisco, San Francisco County, CA

  7. Williams in US Lab

    NASA Image and Video Library

    2010-02-10

    S130-E-006844 (10 Feb. 2010) --- NASA astronaut Jeffrey Williams, Expedition 22 commander, installs a Urine Processor Assembly / Distillation Assembly (UPA DA) in the Water Recovery System (WRS) rack in the Destiny laboratory of the International Space Station while space shuttle Endeavour (STS-130) remains docked with the station.

  8. Profiles in drug metabolism and toxicology: Richard Tecwyn Williams (1909-1979).

    PubMed

    Jones, Alan Wayne

    2015-01-01

    This article pays homage to the life and work of a veritable pioneer in toxicology and drug metabolism, namely a Welshman, Richard Tecwyn Williams, FRS. Professor Williams, or RT as he was known, made major contributions to knowledge about the metabolism and toxicology of drugs and xenobiotics during a scientific career spanning nearly 50 years. Author or coauthor of close to 400 research articles and reviews, including a classic book, entitled Detoxication Mechanisms, Williams and his research school investigated virtually all aspects of drug metabolism, especially conjugations. In particular, the concepts of phase 1 and phase II metabolic pathways were introduced by Williams; the biliary excretion of drugs was extensively studied as were species differences in drug metabolism and detoxication. Besides investigating the metabolism of many pharmaceutical drugs, such as sulfonamides and thalidomide, Williams and his group investigated the disposition and fate in the body of organic pesticides and recreational drugs of abuse, such as amphetamine, methamphetamine and lysergic acid diethylamide (LSD).

  9. Capacity to improve fine motor skills in Williams syndrome.

    PubMed

    Berencsi, A; Gombos, F; Kovács, I

    2016-10-01

    Individuals with Williams syndrome (WS) are known to have difficulties in carrying out fine motor movements; however, a detailed behavioural profile of WS in this domain is still missing. It is also unknown how great the capacity to improve these skills with focused and extensive practice is. We studied initial performance and learning capacity in a sequential finger tapping (FT) task in WS and in typical development. Improvement in the FT task has been shown to be sleep dependent. WS subjects participating in the current study have also participated in earlier polysomnography studies, although not directly related to learning. WS participants presented with great individual variability. In addition to generally poor initial performance, learning capacity was also greatly limited in WS. We found indications that reduced sleep efficiency might contribute to this limitation. Estimating motor learning capacity and the depth of sleep disorder in a larger sample of WS individuals might reveal important relationships between sleep and learning, and contribute to efficient intervention methods improving skill acquisition in WS. © 2016 The Authors. Journal of Intellectual Disability Research published by MENCAP and International Association of the Scientific Study of Intellectual and Developmental Disabilities and John Wiley & Sons Ltd.

  10. Discovering Structure in Auditory Input: Evidence from Williams Syndrome

    ERIC Educational Resources Information Center

    Elsabbagh, Mayada; Cohen, Henri; Karmiloff-Smith, Annette

    2010-01-01

    We examined auditory perception in Williams syndrome by investigating strategies used in organizing sound patterns into coherent units. In Experiment 1, we investigated the streaming of sound sequences into perceptual units, on the basis of pitch cues, in a group of children and adults with Williams syndrome compared to typical controls. We showed…

  11. Dental management of patient with Williams Syndrome - A case report.

    PubMed

    Wong, Daniel; Ramachandra, Srinivas Sulugodu; Singh, Ashish Kumar

    2015-01-01

    Williams syndrome is a multisystemic rare genetic disorder caused by deletion of 26-28 genes in the long arm of chromosome 7. It is characterized by developmental and physical abnormalities including congenital cardiovascular abnormalities, mental retardation, neurological features, growth deficiency, genitourinary manifestations, gastrointestinal problems, musculoskeletal problems, unique behavioral characteristics, and dental problems. Dental abnormalities include malocclusion, hypodontia, malformed teeth, taurodontism, pulp stones, increased space between teeth, enamel hypoplasia, and high prevalence of dental caries. Authors report a 17-year-old female patient with underlying Williams syndrome. Oral features and problems seen in the patient are listed. Malocclusion and screwdriver shaped teeth were noticed. Generalized widening of the periodontal ligament space with vital teeth was seen. This finding has not been reported in cases of Williams syndrome earlier. Precautions taken during dental treatment in patients with Williams syndrome are also discussed.

  12. The Doors to Home and History: Post-Colonial Identities in Meena Alexander and Bharati Mukherjee.

    ERIC Educational Resources Information Center

    Dave, Shilpa

    1993-01-01

    Examines postcolonial inquiry and studies of identity in Asians of Indian descent, focusing on the works of Meena Alexander and Bharati Mukherjee. Their commentaries on India and immigrant cultures are constantly influenced by a history dependent on Western tradition, although both authors resist the stereotypical definitions imposed by the West.…

  13. Recognizing the Presidents: Was Alexander Hamilton President?

    PubMed

    Roediger, Henry L; DeSoto, K Andrew

    2016-05-01

    Studies over the past 40 years have shown that Americans can recall about half the U.S. presidents. Do people know the presidents even though they are unable to access them for recall? We investigated this question using the powerful cues of a recognition test. Specifically, we tested the ability of 326 online subjects to recognize U.S. presidents when presented with their full names among various types of lures. The hit rate for presidential recognition was .88, well above the proportion produced in free recall but far from perfect. Presidents Franklin Pierce and Chester Arthur were recognized less than 60% of the time. Interestingly, four nonpresidents were falsely recognized at relatively high rates, and Alexander Hamilton was more frequently identified as president than were several actual presidents. Even on a recognition test, knowledge of American presidents is imperfect and prone to error. The false alarm data support the theory that false fame can arise from contextual familiarity. © The Author(s) 2016.

  14. 75 FR 16159 - Prince William Sound Regional Citizens' Advisory Council (PWSRCAC) Charter Renewal

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-31

    ... DEPARTMENT OF HOMELAND SECURITY Coast Guard [USCG-2010-0121] Prince William Sound Regional... the Prince William Sound Regional Citizens' Advisory Council (PWSRCAC) as an alternative voluntary advisory group for Prince William Sound, Alaska. This certification allows the PWSRCAC to monitor the...

  15. John Twysden and John Palmer: 17th-century Northamptonshire astronomers

    NASA Astrophysics Data System (ADS)

    Frost, M. A.

    2008-01-01

    John Twysden (1607-1688) and John Palmer (1612-1679) were two astronomers in the circle of Samuel Foster (circa 1600-1652), the subject of a recent paper in this journal. John Twysden qualified in law and medicine and led a peripatetic life around England and Europe. John Palmer was Rector of Ecton, Northamptonshire and later Archdeacon of Northampton. The two astronomers catalogued observations made from Northamptonshire from the 1640s to the 1670s. In their later years Twysden and Palmer published works on a variety of topics, often astronomical. Palmer engaged in correspondence with Henry Oldenburg, the first secretary of the Royal Society, on topics in astronomy and mathematics.

  16. William Wilde and 1 Merrion Square.

    PubMed

    McEntegart, R

    2016-05-01

    William Wilde spent the final third of his life, from 1855 to 1876, in 1 Merrion Square. During the first half of his occupancy of the house his career blossomed to its fullest; the second decade, on the other hand, was marked by scandal, personal tragedy, and an unhappy professional and social decline. This paper considers the background to the development of Merrion Square, the architectural history of 1 Merrion Square from its building in 1762 to the arrival of the Wildes in 1855, the attractions and possibilities which the house offered for William Wilde, the major architectural expansion of the building which he commissioned in 1859, and aspects of his and his family's life in the house.

  17. 78 FR 18616 - Prince William Sound Regional Citizens' Advisory Council (PWSRCAC) Charter Renewal

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-27

    ... DEPARTMENT OF HOMELAND SECURITY Coast Guard [Docket No. USCG-2013-0088] Prince William Sound... the Prince William Sound Regional Citizens' Advisory Council (PWSRCAC) as an alternative voluntary advisory group for Prince William Sound, Alaska. This certification allows the PWSRCAC to monitor the...

  18. 76 FR 24506 - Prince William Sound Regional Citizens' Advisory Council (PWSRCAC) Charter Renewal

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-02

    ... DEPARTMENT OF HOMELAND SECURITY Coast Guard [Docket No. USCG-2011-0142] Prince William Sound... the Prince William Sound Regional Citizens' Advisory Council (PWSRCAC) as an alternative voluntary advisory group for Prince William Sound, Alaska. This certification allows the PWSRCAC to monitor the...

  19. 75 FR 57974 - Senior Executive Service Performance Review Board

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-23

    ... individuals listed below: Aguilar, David V. Alexander, Barbara Alikhan, Arif Anderson, Audrey Anderson, Gary L. Armstrong, Charles R. Ayala, Janice Aytes, Michael L. Bacon, Roxana Baldwin, William D. Baroukh, Nader Barr... N. Muenchau, Ernest Myers, David L. Neal, Jeffrey R. Neufeld, Donald W. Nicholson, David O'Connell...

  20. Speciation despite globally overlapping distributions in Penicillium chrysogenum: the population genetics of Alexander Fleming’s lucky fungus

    USDA-ARS?s Scientific Manuscript database

    Eighty years ago, Alexander Fleming described the antibiotic effects of a fungus that had contaminated his bacterial culture, kick starting the antimicrobial revolution. The fungus was later ascribed to a globally distributed asexual species, Penicillium chrysogenum. Recently, the species has been...

  1. The Alexander N. Charters Library of Resources for Educators of Adults at Syracuse University Library.

    ERIC Educational Resources Information Center

    Keenan, Terrance

    This document describes the contents of the Alexander N. Charters Library of Resources for Educators of Adults at Syracuse University Library. The document begins with a brief history of the development of the library's collections, which occupy 900 feet of shelf space and contain more than 50 groups of personal papers and records of organizations…

  2. Earthquake Signatures in the Modern Sediment Record of Prince William Sound, Alaska

    NASA Astrophysics Data System (ADS)

    Marshall, N. R.; Kuehl, S. A.; Dellapenna, T. M.; Miller, E. J.

    2016-02-01

    Geochemical signatures of earthquake-generated sediment gravity flows are investigated using X-ray fluorescence core scanning on a suite of sediment cores from Prince William Sound, Alaska. This study focused on the development of geochemical proxies for earthquake deposits with an emphasis on interpreting deposits initiated from large subduction earthquakes. A north-south transect of sediment cores from Prince William Sound, between Hinchinbrook Island and the Columbia Glacier, was used to examine a record of earthquakes in this tectonically active region for the past century. The sediments in Prince William Sound are sourced from two geologically distinct regions: the metamorphosed turbidites of coastal Prince William Sound, and the Copper River Basin that contains a significant amount of volcanic rocks. Geochemical studies of sediment cores and end-member sediment samples using X-ray fluorescence and inductively coupled plasma mass spectrometry allowed for the development of geochemical proxies for sediment provenance during the past 100 years. Downcore peaks in Sr/Pb are indicative of Copper River Basin sediments, whereas peaks in K/Ca are indicative of inputs of Prince William Sound sediments. Large subduction earthquakes in northern Prince William Sound initiate gravity flows of Prince William Sound provenance into the deep channel. Particularly robust provenance signatures are seen in the northernmost cores in the core transect, which are closer to the earthquake epicenters and the Columbia Glacier source region. The ages of the deposits, from core-averaged 210Pb sediment accumulation rates, correspond to large earthquakes that occurred in 1912, 1964, and 1983. A similar deposit from 1895 in northern Prince William Sound, prior to historical earthquake records, may have also been initiated from a large earthquake in the 1890's.

  3. Sir John Macpherson, the first but sometimes overlooked Professor of Psychiatry at the University of Sydney.

    PubMed

    White, Richard T

    2014-08-01

    To chronicle the creation of the Chair of Psychiatry at the University of Sydney, and the career and legacy, in New South Wales, of the first incumbent, Professor Sir John Macpherson CB MD FRCPE. The creation of the Chair, Macpherson's appointment, and his contributions to psychiatry in Sydney during the 52 months of his tenure, are well documented in contemporaneous sources and demonstrate that he was a very worthy Foundation Professor of Psychiatry at the University of Sydney. There are several possible reasons why Macpherson has been overlooked, including an erroneous statement in The World History of Psychiatry (1975) that William Siegfried Dawson, his successor from 1927 to 1952, was the first Professor of Psychiatry. © The Royal Australian and New Zealand College of Psychiatrists 2014.

  4. Williams cuts his hair in the SM during Expedition 13

    NASA Image and Video Library

    2006-05-09

    ISS013-E-17184 (9 May 2006) --- Astronaut Jeffrey N. Williams, Expedition 13 NASA space station science officer and flight engineer, trims his hair in the Zarya module of the International Space Station. Williams used hair clippers fashioned with a vacuum device to garner freshly cut hair.

  5. John Lewis | NREL

    Science.gov Websites

    Lewis John Lewis John Lewis Researcher IV-Chemical Engineering John.Lewis@nrel.gov | 303-275-3021 Education Ph.D. Chemical Engineering, California Institute of Technology, Pasadena, CA, 1996 M.S. Chemical Engineering, California Institute of Technology, Pasadena, CA, 1993 B.S. Chemical Engineering, Texas A&M

  6. The use of emotions in narratives in Williams syndrome.

    PubMed

    Van Herwegen, Jo; Aznar, Ana; Tenenbaum, Harriet

    2014-01-01

    Although individuals with Williams syndrome are very sociable, they tend to have limited contact and friendships with peers. In typically developing children the use of positive emotions (e.g., happy) has been argued to be related to peer relationships and popularity. The current study investigated the use and development of emotion words in Williams syndrome using cross-sectional developmental trajectories and examined children's use of different types of emotion words. Nineteen children with Williams syndrome (WS) and 20 typically developing (TD) children matched for chronological age told a story from a wordless picture book. Participants with WS produced a similar number of emotion words compared to the control group and the use of emotion words did not change when plotted against chronological age or vocabulary abilities in either group. However, participants with WS produced more emotion words about sadness. Links between emotion production and friendships as well as future studies are discussed. After reading this article, readers will be able to: explain the development of positive and negative emotions in Williams syndrome and recognize that emotion production is atypical in this population. Copyright © 2014 Elsevier Inc. All rights reserved.

  7. Palaeoglaciology of the Alexander Island ice cap, western Antarctic Peninsula, reconstructed from marine geophysical and core data

    NASA Astrophysics Data System (ADS)

    Graham, Alastair G. C.; Smith, James A.

    2012-03-01

    The glacial history of the continental shelf northwest of Alexander Island is not well known, due mainly to a lack of targeted marine data on Antarctica's palaeo-ice sheets in their inter-ice-stream areas. Recently it has been argued that the region was ice-free at the Last Glacial Maximum (LGM) and thus a potential site for glacial refugia. In this paper, multibeam swath bathymetry, sub-bottom profiles and sediment cores are used to map the Alexander Island sector of the Antarctic Peninsula margin, in order to reconstruct the shelf's palaeoglaciology. Sea-floor bedforms provide evidence that an independent ice cap persisted on Alexander Island through the LGM and deglaciation. We show that this ice cap drained via two major, previously-undescribed tidewater outlets (Rothschild and Charcot Glaciers) sourced from an ice dome centred over the west of the island and near-shore areas. The glaciers grounded along deep, fjord-like cross-shelf troughs to within at least ˜10-20 km of the shelf edge, and probably reached the shelf break. Only one small outer-shelf zone appears to have remained free of ice throughout an otherwise extensive LGM. During retreat, grounding-line geomorphology indicates periodic stabilisation of Charcot Glacier on the mid-shelf after 13,500 cal yrs BP, while Rothschild Glacier retreated across its mid-shelf by 14,450 cal yrs BP. The timing of these events is in phase with retreat in nearby Marguerite Trough, and we take this as evidence of a common history and forcing with the Antarctic Peninsula Ice Sheet. The fine details of ice flow documented by our new reconstruction highlight the importance of capturing complex ice flow patterns in models (e.g. in inter-stream areas), for understanding how region-specific parts of Antarctica may change in the future. Moreover, the reconstruction shows that glacial refugia, if present, cannot have been extensive on the Alexander Island shelf at the LGM as indicated by previous biological studies; instead

  8. Probed Serial Recall in Williams Syndrome: Lexical Influences on Phonological Short-Term Memory

    ERIC Educational Resources Information Center

    Brock, Jan; McCormack, Teresa; Boucher, Jill

    2005-01-01

    Williams syndrome is a genetic disorder that, it has been claimed, results in an unusual pattern of linguistic strengths and weaknesses. The current study investigated the hypothesis that there is a reduced influence of lexical knowledge on phonological short-term memory in Williams syndrome. Fourteen children with Williams syndrome and 2…

  9. Pursuing the Panderer: An Analysis of "United States v. Williams"

    ERIC Educational Resources Information Center

    McGrain, Patrick N.; Moore, Jennifer L.

    2010-01-01

    In May 2008, the Supreme Court addressed whether the government can regulate the ownership and distribution of virtual child pornography. "U.S. v. Williams" marked the first time the Court directly addressed the concept of pandering virtual child pornography. This article examines the Court's decision in "U.S. v. Williams" and…

  10. Specialized Preparation for Middle Level Teachers: A National Review of Teacher Preparation Programs

    ERIC Educational Resources Information Center

    Howell, Penny B.; Faulkner, Shawn A.; Cook, Chris M.; Miller, Nicole C.; Thompson, Nicole L.

    2016-01-01

    Since William Alexander's (1963, 1995) call for attention to the need for specialized middle level teacher preparation in 1963, 45 states have created requirements for middle level certification, licensure, or endorsement (Association for Middle Level Education [AMLE], 2014) which have led to institutions of teacher preparation creating routes…

  11. Unveiling of sign for Walter C. Williams Research Aircraft Integration Facility

    NASA Technical Reports Server (NTRS)

    1995-01-01

    In a brief ceremony following a memorial service for the late Walter C. Williams on November 17, 1995, the Integrated Test Facility (ITF) at the NASA Dryden Flight Research Center at Edwards, California, was formally renamed the Walter C. Williams Research Aircraft Integration Facility. Shown is the family of Walt Williams: Helen, his widow, sons Charles and Howard, daughter Elizabeth Williams Powell, their spouses and children unveiling the new sign redesignating the Facility. The test facility provides state-of-the-art capabilities for thorough ground testing of advanced research aircraft. It allows researchers and technicians to integrate and test aircraft systems before each research flight, which greatly enhances the safety of each mission. In September 1946 Williams became engineer-in-charge of a team of five engineers who arrived at Muroc Army Air Base (now Edwards AFB) from the National Advisory Committee for Aeronautics's Langley Memorial Aeronautical Laboratory, Hampton, Virginia (now NASA's Langley Research Center), to prepare for supersonic research flights in a joint NACA-Army Air Forces program involving the rocket-powered X-1. This established the first permanent NACA presence at the Mojave Desert site although initially the five engineers and others who followed them were on temporary assignment. Over time, Walt continued to be in charge during the many name changes for the NACA-NASA organization, with Williams ending his stay as Chief of the NASA Flight Research Center in September 1959 (today NASA's Dryden Flight Research Center).

  12. Using novel control groups to dissect the amygdala's role in Williams syndrome.

    PubMed

    Thornton-Wells, Tricia A; Avery, Suzanne N; Blackford, Jennifer Urbano

    2011-07-01

    Williams syndrome is a neurodevelopmental disorder with an intriguing behavioral phenotype-hypersociability combined with significant non-social fears. Previous studies have demonstrated abnormalities in amygdala function in individuals with Williams syndrome compared to typically-developing controls. However, it remains unclear whether the findings are related to the atypical neurodevelopment of Williams syndrome, or are also associated with behavioral traits at the extreme end of a normal continuum. We used functional magnetic resonance imaging (fMRI) to compare amygdala blood-oxygenation-level-dependent (BOLD) responses to non-social and social images in individuals with Williams syndrome compared to either individuals with inhibited temperament (high non-social fear) or individuals with uninhibited temperament (high sociability). Individuals with Williams syndrome had larger amygdala BOLD responses when viewing the non-social fear images than the inhibited temperament control group. In contrast, when viewing both fear and neutral social images, individuals with Williams syndrome did not show smaller amygdala BOLD responses relative to the uninhibited temperament control group, but instead had amygdala responses proportionate to their sociability. These results suggest heightened amygdala response to non-social fear images is characteristic of WS, whereas, variability in amygdala response to social fear images is proportionate to, and might be explained by, levels of trait sociability.

  13. William J. Glackens: "The Cedar Walk."

    ERIC Educational Resources Information Center

    Davidson, Marilyn

    1986-01-01

    Provides a lesson plan for primary grade-level students based on William J. Glackens' oil painting, "The Cedar Walk." The goal of the lesson is to introduce students to landscape/seascape painting. (JDH)

  14. 76 FR 1187 - Application for Recertification of Prince William Sound Regional Citizens' Advisory Council

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-07

    ... Prince William Sound Regional Citizens' Advisory Council AGENCY: Coast Guard, DHS. ACTION: Notice of... on, the application for recertification submitted by the Prince William Sound Regional Citizen's... advisory group in lieu of a Regional Citizens' Advisory Council for Prince William Sound, Alaska. This...

  15. FE Williams exercising on the CEVIS

    NASA Image and Video Library

    2012-07-21

    ISS032-E-008595 (20 July 2012) --- NASA astronaut Sunita Williams, Expedition 32 flight engineer, exercises on the Cycle Ergometer with Vibration Isolation System (CEVIS) in the Destiny laboratory of the International Space Station.

  16. Balancing Congressional Needs for Classified Information: A Case Study of the Strategic Defense initiative

    DTIC Science & Technology

    1993-05-17

    Star Wars." Arms Control Today, May 1992, 29-30. Saucier, Aldric. "Lost in Space." New York Times, 9 March 1992, A17. Savelyev , Alexander . "Toward U.S...legislature will be unable to retain the secrecy of such material. In recent years, the 22 Alexander Hamilton, James Madison and John Jay, The Federalist...The Struggle for Democracy in America. Cambridge, Massachusetts: The Riverside Press, 1925. Boyd, Julian P. Number 7: Alexander Hamilton’s Secret

  17. Williams performs IFM during Expedition 13

    NASA Image and Video Library

    2006-08-24

    ISS013-E-70896 (24 Aug. 2006) --- Astronaut Jeffrey N. Williams, Expedition 13 NASA space station science officer and flight engineer, performs in-flight maintenance (IFM) in the Destiny laboratory of the International Space Station.

  18. International Program and Local Organizing Committees

    NASA Astrophysics Data System (ADS)

    2012-12-01

    International Program Committee Dionisio Bermejo (Spain) Roman Ciurylo (Poland) Elisabeth Dalimier (France) Alexander Devdariani (Russia) Milan S Dimitrijevic (Serbia) Robert Gamache (USA) Marco A Gigosos (Spain) Motoshi Goto (Japan) Magnus Gustafsson (Sweden) Jean-Michel Hartmann (France) Carlos Iglesias (USA) John Kielkopf (USA) John C Lewis (Canada) Valery Lisitsa (Russia) Eugene Oks (USA) Christian G Parigger (USA) Gillian Peach (UK) Adriana Predoi-Cross (Canada) Roland Stamm (Germany) Local Organizing Committee Nikolay G Skvortsov (Chair, St Petersburg State University) Evgenii B Aleksandrov (Ioffe Physico-Technical Institute, St Petersburg) Vadim A Alekseev (Scientific Secretary, St Petersburg State University) Sergey F Boureiko (St.Petersburg State University) Yury N Gnedin (Pulkovo Observatory, St Petersburg) Alexander Z Devdariani (Deputy Chair, St Petersburg State University) Alexander P Kouzov (Deputy Chair, St Petersburg State University) Nikolay A Timofeev (St Petersburg State University)

  19. Teaching in the Middle Grades Today: Examining Teachers' Beliefs about Middle Grades Teaching

    ERIC Educational Resources Information Center

    DiCicco, Mike; Cook, Chris M.; Faulkner, Shawn A.

    2016-01-01

    Since the beginning of the middle school movement in the mid-1960s, middle level advocates have called for a school experience for young adolescents grounded in adolescent development that engages students in meaningful learning (Alexander & Williams, 1965; Eichhorn, 1966). The aim of this exploratory multicase study was to understand middle…

  20. Commemorating John Dyson

    NASA Astrophysics Data System (ADS)

    Pittard, Julian M.

    2015-03-01

    John Dyson was born on the 7th January 1941 in Meltham Mills, West Yorkshire, England, and later grew up in Harrogate and Leeds. The proudest moment of John's early life was meeting Freddie Trueman, who became one of the greatest fast bowlers of English cricket. John used a state scholarship to study at Kings College London, after hearing a radio lecture by D. M. McKay. He received a first class BSc Special Honours Degree in Physics in 1962, and began a Ph.D. at the University of Manchester Department of Astronomy after being attracted to astronomy by an article of Zdenek Kopal in the semi-popular journal New Scientist. John soon started work with Franz Kahn, and studied the possibility that the broad emission lines seen from the Orion Nebula were due to flows driven by the photoevaporation of neutral globules embedded in a HII region. John's thesis was entitled ``The Age and Dynamics of the Orion Nebula`` and he passed his oral examination on 28th February 1966.

  1. Tennessee Williams: the uses of declarative memory in The Glass Menagerie.

    PubMed

    Jacobs, Daniel

    2002-01-01

    Tennessee Williams called his first great work, The Glass Menagerie, his "memory play." The situation in which Williams found himself when he began writing the play is explored, as are the ways in which he used the declarative memory of his protagonist, Tom Wingfield, to express and deal with his own painful conflicts. Williams's use of stage directions, lighting, and music to evoke memory and render it three-dimensional is described. Through a close study of The Glass Menagerie, the many uses of memory for the purposes of wish fulfillment, conflict resolution, and resilience are examined.

  2. William Heard Kilpatrick: A Memoir.

    ERIC Educational Resources Information Center

    Van Til, William

    1988-01-01

    A memoir about William Heard Kilpatrick examines his style as a master teacher and leader of educational organizations during the 1930's, providing a personal account of this teacher whose huge classes brought in over $1 million in tuition fees. He promoted progressive education and advocated recognition of individual differences. (SM)

  3. Learning by observation: insights from Williams syndrome.

    PubMed

    Foti, Francesca; Menghini, Deny; Mandolesi, Laura; Federico, Francesca; Vicari, Stefano; Petrosini, Laura

    2013-01-01

    Observing another person performing a complex action accelerates the observer's acquisition of the same action and limits the time-consuming process of learning by trial and error. Observational learning makes an interesting and potentially important topic in the developmental domain, especially when disorders are considered. The implications of studies aimed at clarifying whether and how this form of learning is spared by pathology are manifold. We focused on a specific population with learning and intellectual disabilities, the individuals with Williams syndrome. The performance of twenty-eight individuals with Williams syndrome was compared with that of mental age- and gender-matched thirty-two typically developing children on tasks of learning of a visuo-motor sequence by observation or by trial and error. Regardless of the learning modality, acquiring the correct sequence involved three main phases: a detection phase, in which participants discovered the correct sequence and learned how to perform the task; an exercise phase, in which they reproduced the sequence until performance was error-free; an automatization phase, in which by repeating the error-free sequence they became accurate and speedy. Participants with Williams syndrome beneficiated of observational training (in which they observed an actor detecting the visuo-motor sequence) in the detection phase, while they performed worse than typically developing children in the exercise and automatization phases. Thus, by exploiting competencies learned by observation, individuals with Williams syndrome detected the visuo-motor sequence, putting into action the appropriate procedural strategies. Conversely, their impaired performances in the exercise phases appeared linked to impaired spatial working memory, while their deficits in automatization phases to deficits in processes increasing efficiency and speed of the response. Overall, observational experience was advantageous for acquiring competencies

  4. Alexander F. Chamberlain: a life's work.

    PubMed

    Berkman, Julia M

    2005-01-01

    This article examines the life and work of Alexander Francis Chamberlain. Though he has received little attention since the early 1900s, the importance of this scholar should not be underestimated. Chamberlain made notable contributions to the body of knowledge in anthropology-a discipline that, at the time, was a combination of anthropological and psychological inquiry. His early work began with investigations into the cultures and languages of two Indian tribes indigenous to Canada and the northern United States and, within a few decades, positioned Chamberlain as the leading scholar in this domain. Beyond his ethnographic insights, Chamberlain queried the development of the child and wrote on the subject of childhood in world folklore. He concerned himself with a scope of worthwhile subjects ranging from linguistics to women's suffrage. No topic was out of range as all forms of human study addressed the need for seeing each group as a contributing force to humanity at large. Chamberlain emphasized that no single racial, ethnic, or religious group should be singled out as inherently superior to another, a belief far ahead of his time. This article is an attempt at drawing a picture of a man whose scholarly achievements and strength of character are captured in the depth and breadth of his writing.

  5. Silurian Gastropoda from the Alexander terrane, southeast Alaska

    USGS Publications Warehouse

    Rohr, D.M.; Blodgett, R.B.

    2008-01-01

    Gastropods are described from Ludlow-age strata of the Heceta Limestone on Prince of Wales Island, southeast Alaska. They are part of a diverse megabenthic fauna of the Alexander terrane, an accreted terrane of Siberian or Uralian affinities. Heceta Limestone gastropods with Uralian affinities include Kirkospira glacialis, which closely resembles "Pleurotomaria" lindstromi Oehlert of Chernyshev, 1893, Retispira cf. R. volgulica (Chernyshev, 1893), and Medfracaulus turriformis (Chernyshev, 1893). Medfracaulus and similar morphotypes such as Coelocaulus karlae are unknown from rocks that are unquestionably part of the North American continent (Laurentia) during Late Silurian time. Beraunia is previously known only from the Silurian of Bohemia. Pachystrophia has previously been reported only from western North American terranes (Eastern Klamath, York, and Farewell terranes) and Europe. Bathmopterus Kirk, 1928, is resurrected and is only known from the Silurian of southeast Alaska. Newly described taxa include Hecetastoma gehrelsi n. gen. and n. sp. and Baichtalia tongassensis n. gen. and n. sp. ??2008 The Geological Society of America.

  6. Expedition 8 Crew Interviews: Alexander Y. Kaleri - FE

    NASA Technical Reports Server (NTRS)

    2003-01-01

    Russian cosmonaut Alexander Y. Kaleri, Flight Engineer on Expedition 8 to the International Space Station (ISS), answers interview questions on this video, either himself or with the help of an interpreter. The questions cover: 1) The goal of the expedition; 2) The place in history of Mir; 3) The reaction to the loss of Columbia in Houston; 4) Why the rewards of spaceflight are worth the risks; 5) Why he decided to become a cosmonaut; 6) His memory of Yuri Gagarin's first flight; 7) What happens on a Soyuz capsule during launch and flight; 8) Are Soyuz maneuvers automatic or manual; 8) How the ISS science mission will be advanced during his stay; 9) The responsibilities of a Flight Engineer onboard the ISS; 10) Extravehicular activity (EVA) plans at that time; 11) The Shuttle Return to Flight and his preference for a Shuttle or Soyuz landing; 12) Why the last Soyuz landing was too rough; 13) The most valueable contribution of the ISS program.

  7. Valuing Higher Education: An Appreciation of the Work of Gareth Williams

    ERIC Educational Resources Information Center

    Barnett, Ronald, Ed.; Temple, Paul, Ed.; Scott, Peter, Ed.

    2016-01-01

    In "Valuing Higher Education," leading international analysts examine Gareth Williams's contribution to shaping our thinking about the economics of higher education in essays that are a testimony to Williams's conception that the field cannot be properly understood unless viewed alongside social policy, changes in knowledge production,…

  8. Williams exercises on TVIS in Zvezda

    NASA Image and Video Library

    2007-12-28

    ISS014-E-10591 (28 Dec. 2006) --- Astronaut Sunita L. Williams, Expedition 14 flight engineer, equipped with a bungee harness, exercises on the Treadmill Vibration Isolation System (TVIS) in the Zvezda Service Module of the International Space Station.

  9. Williams configures the LMM

    NASA Image and Video Library

    2016-04-18

    ISS047e066551 (04/18/2016) --- NASA astronaut Jeff Williams configures the station’s Light Microscopy Module (LMM), a modified commercial, highly flexible, state-of-the-art light imaging microscope facility that provides researchers with powerful diagnostic hardware and software. The LMM enables novel research of microscopic phenomena in microgravity, with the capability of remotely acquiring and downloading digital images and videos across many levels of magnification.

  10. Williams working on the JAXA MS (Marangoni Surface) Experiment

    NASA Image and Video Library

    2009-11-05

    ISS021-E-020304 (5 Nov. 2009) --- NASA astronaut Jeffrey Williams, Expedition 21 flight engineer, works with Fluid Physics Experiment Facility/Marangoni Surface (FPEF MS) Core hardware in the Kibo laboratory of the International Space Station. Williams first inserted the Marangoni Inside (MI) cassette in the MI Core for a leak check, and then installed the MI Core into the FPEF MI Body. The Marangoni convection experiment in the FPEF examines fluid tension flow in micro-G.

  11. Wilde's worlds: Sir William Wilde in Victorian Ireland.

    PubMed

    McGeachie, J

    2016-05-01

    Other contributors to this collection have evoked the disparate worlds inhabited by Sir William Wilde. To provide an overall assessment of his career. Looking at the historical conditions that made possible such a career spanning such disparate worlds. Deploying methodologies developed by historians of medicine and sociologists of science, the article brings together Wilde the nineteenth century clinician and Dublin man of science, the Wilde of the Census and of the west of Ireland, William Wilde Victorian medical man and Wilde the Irish medical man-the historian of Irish medical traditions and the biographer of Irish medical men, and William Wilde as an Irish Victorian. A variety of close British Isles parallels can be drawn between Wilde and his cohort in the medical elite of Dublin and their clinical peers in Edinburgh and London both in terms of clinical practice and self-presentation and in terms of the social and political challenges facing their respective ancient regime hegemonies in an age of democratic radicalisation. The shared ideological interests of Wilde and his cohort, however, were also challenged by the socio-political particularities and complexities of Ireland during the first half of the nineteenth century culminating in the catastrophe of the Great Famine. William Wilde saw the practice of scientific medicine as offering a means of deliverance from historical catastrophe for Irish society and invoked a specifically Irish scientific and medical tradition going back to the engagement with the condition of Ireland by enlightened medical men in the seventeenth and eighteenth centuries.

  12. Bridging the Gap: Higher Education and Career-Centered Welfare Reform. Proceedings.

    ERIC Educational Resources Information Center

    Kosar, Kevin R., Ed.

    This conference examined the current welfare policy and the continued use of higher education as a tool for moving low-income people into self-supporting careers. The proceedings include: welcoming remarks by Stephen Greenwald; keynote addresses by William Spriggs and Danny Simmons; a lunch address by Rae Alexander-Minter; remarks by Patricia…

  13. Teaching Privacy in the Twenty-First Century

    ERIC Educational Resources Information Center

    Edbrooke, Odette; Ambrose, Meg Leta

    2012-01-01

    What would Benjamin Franklin's Facebook page look like? Would he be "friends" with William Pierce, James Madison, or Alexander Hamilton? Would there have been a separate Facebook group for the framers of the Constitution, where they would have posted comments on the wall regarding the different stipulations that needed inclusion in the…

  14. Williams in Node 1 / Unity module

    NASA Image and Video Library

    2007-03-01

    ISS014-E-15830 (4 March 2007) --- Astronaut Sunita L. Williams, Expedition 14 flight engineer, works with a portion of the Treadmill Vibration Isolation System (TVIS) during in-flight maintenance (IFM) in the Unity node of the International Space Station.

  15. 40 CFR Appendix B to Part 425 - Modified Monier-Williams Method

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 30 2011-07-01 2011-07-01 false Modified Monier-Williams Method B... Part 425—Modified Monier-Williams Method Outline of Method Hydrogen sulfide is liberated from an.... Quality Control 1. Each laboratory that uses this method is required to operate a formal quality control...

  16. 40 CFR Appendix B to Part 425 - Modified Monier-Williams Method

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 29 2010-07-01 2010-07-01 false Modified Monier-Williams Method B... Part 425—Modified Monier-Williams Method Outline of Method Hydrogen sulfide is liberated from an.... Quality Control 1. Each laboratory that uses this method is required to operate a formal quality control...

  17. 78 FR 11857 - Agency Information Collection Activities; Comment Request; William D. Ford Federal Direct Loan...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-20

    ...; Comment Request; William D. Ford Federal Direct Loan Program (DL) Regulations AGENCY: Department of... in response to this notice will be considered public records. Title of Collection: William D. Ford.... Abstract: The William D. Ford Federal Direct Loan Program regulations cover areas of program administration...

  18. 40 CFR Appendix B to Part 425 - Modified Monier-Williams Method

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 31 2012-07-01 2012-07-01 false Modified Monier-Williams Method B... Appendix B to Part 425—Modified Monier-Williams Method Outline of Method Hydrogen sulfide is liberated from.... Quality Control 1. Each laboratory that uses this method is required to operate a formal quality control...

  19. Solomon Receives 2007 William Bowie Medal

    NASA Astrophysics Data System (ADS)

    Brasseur, Guy; Solomon, Susan

    2008-01-01

    Susan Solomon was awarded the 2007 William Bowie Medal at the AGU Fall Meeting Honors Ceremony, which was held on 12 December 2007 in San Francisco, Calif. The medal is for ``outstanding contributions to fundamental geophysics and for unselfish cooperation in research.''

  20. 75 FR 81640 - President William Jefferson Clinton Birthplace Home National Historic Site

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-28

    ... Jefferson Clinton Birthplace Home National Historic Site AGENCY: National Park Service, Interior. ACTION..., Hope, Arkansas 71801, as the ``President William Jefferson Clinton Birthplace Home National Historic... Birthplace Foundation, Inc., fee simple, unencumbered title to the William Jefferson Clinton Birthplace Home...

  1. Local knowledge, state power, and the science of industrial labor relations: William Leiserson, David Saposs, and American labor economics in the interwar years.

    PubMed

    Wang, Jessica

    2010-01-01

    Recent scholarship has frequently emphasized modern states' use of social science to impose universalized conceptions of rationality and order upon diverse, highly localized settings. The New Deal era experiences of William M. Leiserson and David J. Saposs, however, provide an analytical alternative. As students of the pioneering labor economist John R. Commons, Leiserson and Saposs sought to create mechanisms for state oversight of industrial labor relations that recognized local practices and arrangements. Although their approach failed to take hold within the National Labor Relations Board, localized institutional and political contingencies, and not a hegemonic modernism, account best for their frustrated aspirations in the late 1930s. © 2010 Wiley Periodicals, Inc.

  2. The Williams' legacy: A critical reappraisal of his nine predictions about the evolution of senescence.

    PubMed

    Gaillard, Jean-Michel; Lemaître, Jean-François

    2017-12-01

    Williams' evolutionary theory of senescence based on antagonistic pleiotropy has become a landmark in evolutionary biology, and more recently in biogerontology and evolutionary medicine. In his original article, Williams launched a set of nine "testable deductions" from his theory. Although some of these predictions have been repeatedly discussed, most have been overlooked and no systematic evaluation of the whole set of Williams' original predictions has been performed. For the sixtieth anniversary of the publication of the Williams' article, we provide an updated evaluation of all these predictions. We present the pros and cons of each prediction based on recent accumulation of both theoretical and empirical studies performed in the laboratory and in the wild. From our viewpoint, six predictions are mostly supported by our current knowledge at least under some conditions (although Williams' theory cannot thoroughly explain why for some of them). Three predictions, all involving the timing of senescence, are not supported. Our critical review of Williams' predictions highlights the importance of William's contribution and clearly demonstrates that, 60 years after its publication, his article does not show any sign of senescence. © 2017 The Author(s). Evolution © 2017 The Society for the Study of Evolution.

  3. Music and Anxiety in Williams Syndrome: A Harmonious or Discordant Relationship?

    ERIC Educational Resources Information Center

    Dykens, Elisabeth M.; Rosner, Beth A.; Ly, Tran; Sagun, Jaclyn

    2005-01-01

    In this two-part study, we assessed musical involvements in two samples of persons with Williams syndrome compared to others with mental retardation and also related musicality to anxiety and fears in Study 2. Relative to others with mental retardation, those with Williams syndrome were more likely to take music lessons, play an instrument, and…

  4. The Alexander Technique and musicians: a systematic review of controlled trials.

    PubMed

    Klein, Sabine D; Bayard, Claudine; Wolf, Ursula

    2014-10-24

    Musculoskeletal disorders, stress and performance anxiety are common in musicians. Therefore, some use the Alexander Technique (AT), a psycho-physical method that helps to release unnecessary muscle tension and re-educates non-beneficial movement patterns through intentional inhibition of unwanted habitual behaviours. According to a recent review AT sessions may be effective for chronic back pain. This review aimed to evaluate the evidence for the effectiveness of AT sessions on musicians' performance, anxiety, respiratory function and posture. The following electronic databases were searched up to February 2014 for relevant publications: PUBMED, Google Scholar, CINAHL, EMBASE, AMED, PsycINFO and RILM. The search criteria were "Alexander Technique" AND "music*". References were searched, and experts and societies of AT or musicians' medicine contacted for further publications. 237 citations were assessed. 12 studies were included for further analysis, 5 of which were randomised controlled trials (RCTs), 5 controlled but not randomised (CTs), and 2 mixed methods studies. Main outcome measures in RCTs and CTs were music performance, respiratory function, performance anxiety, body use and posture. Music performance was judged by external experts and found to be improved by AT in 1 of 3 RCTs; in 1 RCT comparing neurofeedback (NF) to AT, only NF caused improvements. Respiratory function was investigated in 2 RCTs, but not improved by AT training. Performance anxiety was mostly assessed by questionnaires and decreased by AT in 2 of 2 RCTs and in 2 of 2 CTs. A variety of outcome measures has been used to investigate the effectiveness of AT sessions in musicians. Evidence from RCTs and CTs suggests that AT sessions may improve performance anxiety in musicians. Effects on music performance, respiratory function and posture yet remain inconclusive. Future trials with well-established study designs are warranted to further and more reliably explore the potential of AT in the

  5. Walter C. Williams (1919-1995)

    NASA Technical Reports Server (NTRS)

    1954-01-01

    Walter C. Williams was Chief of the National Advisory Committee for Aeronautics' and the National Aeronautics and Space Administration's flight research organization on Edwards Air Force Base until his appointment as Associate Director of Project Mercury on September 15, 1959. Walt had started his career with NACA at Langley Memorial Aeronautical Laboratory in 1939 as an engineer in the Flight Division. In 1946 he transferred to the Muroc Army Air Field to be in charge of the small group of technicians and engineers who would be doing the flight research on a joint NACA-Army Air Forces program involving the rocket-powered Bell XS-1. See photo DIRECTORS E-49-0170, which addresses the first eight years of Walt's responsibilities with NACA. Williams' achievements as Chief of the NACA/NASA High-Speed Flight Station for the next five years continued to be significant. NACA pilot Joseph A. Walker made the first of 20 NACA research flights in the Douglas X-3 'Flying Stiletto'--on which inertial coupling was first experience--in 1954. The first NACA flight in an Lockheed F-104A aircraft occurred on August 27, 1956. On October 15, 1958, the first of three North American X-15 rocket research aircraft arrived at NASA High Speed Flight Station as preparations moved ahead for the highly successful NASA-Air Force-Navy-North American program that would last 10 years and investigate hypersonic flight. Walt directed a great variety of other flight research programs, including that on the Boeing B-47; investigations using the Century Series fighters, F-100, F-102, F-104, F-105 and F-107; and the ones involving the X-1 #2, which became the X1-E. During Williams' career, he twice received the NASA Distinguished Service Medal and was nominated both to the Meritorious Rank and Distinguished Rank in the Federal Senior Executive Service. In 1963 he was awarded an honorary doctorate of engineering degree by Louisiana State University. He received several awards from the American Institute

  6. Who Was the Real William Shakespeare?

    ERIC Educational Resources Information Center

    Edwards, Michael Todd

    2009-01-01

    This article highlights a project that encourages students to connect reading and mathematics instruction by using a data analysis approach. Students analyze sonnets from statistical, literary, and historical points of view in an effort to uncover the true identity of William Shakespeare. (Contains 10 figures.)

  7. Mr. William Shakespeare and the Internet.

    ERIC Educational Resources Information Center

    Reeves, Barbara

    2000-01-01

    Describes resources and links on a Web site entitled "Mr. William Shakespeare and the Internet," with suggestions for using them with students. Highlights include: historical context; impact of events/situations on works; motivational/preparatory lessons; reading and understanding Shakespeare; analysis of works; language; assessing other…

  8. MacWilliams Identity for M-Spotty Weight Enumerator

    NASA Astrophysics Data System (ADS)

    Suzuki, Kazuyoshi; Fujiwara, Eiji

    M-spotty byte error control codes are very effective for correcting/detecting errors in semiconductor memory systems that employ recent high-density RAM chips with wide I/O data (e.g., 8, 16, or 32bits). In this case, the width of the I/O data is one byte. A spotty byte error is defined as random t-bit errors within a byte of length b bits, where 1 le t ≤ b. Then, an error is called an m-spotty byte error if at least one spotty byte error is present in a byte. M-spotty byte error control codes are characterized by the m-spotty distance, which includes the Hamming distance as a special case for t =1 or t = b. The MacWilliams identity provides the relationship between the weight distribution of a code and that of its dual code. The present paper presents the MacWilliams identity for the m-spotty weight enumerator of m-spotty byte error control codes. In addition, the present paper clarifies that the indicated identity includes the MacWilliams identity for the Hamming weight enumerator as a special case.

  9. Riding on the Back of a Giant: Adding Malta to the "5 Cultures" Study by Robin Alexander

    ERIC Educational Resources Information Center

    Peresso, Randolph

    2017-01-01

    This paper focuses on the methodology adopted for Malta+5, which builds on Robin Alexander's work by comparing the five pedagogical cultures he studied to the one in Malta. It reflects critically on the research process adopted in this study, and shows how, despite the very limited experience and resources, applying the methodology, frameworks and…

  10. Honors

    NASA Astrophysics Data System (ADS)

    2013-03-01

    Four AGU members are among the 18 individuals the U.S. National Academy of Sciences (NAS) will honor during its 150th annual meeting in April. William J. Borucki, space scientist at the NASA Ames Research Laboratory and science principal investigator for the Kepler Mission, is the recipient of the Henry Draper Medal "for his founding concept and visionary leadership of Kepler." John Gosling, senior research associate in the Laboratory for Atmospheric and Space Physics at the University of Colorado, Boulder, and retired laboratory fellow at Los Alamos National Laboratory, will receive the Arctowski Medal. Gosling was selected for his work on the generation of energetic solar events, including distinguishing solar flares and coronal mass ejections. David Karl, professor of oceanography at the University of Hawai`i, Mānoa, is the recipient of the Alexander Agassiz Medal. NAS notes Karl's leadership in establishing multidisciplinary ocean-observing systems, detecting decadal regime shifts in pelagic ecosystems, and insights on biogeochemical cycles in the ocean. J. William Schopf, distinguished professor of paleobiology at the University of California, Los Angeles, is the recipient of the NAS Award in Early Earth and Life Sciences, presented in 2013 with the Charles Doolittle Walcott Medal. Schopf is being honored for his studies of microscopic fossils that represent the earliest forms of life on Earth and for leadership of large collaborative research groups.

  11. Sir William Hingston

    PubMed Central

    Cohen, Jack

    1996-01-01

    Sir William Hingston was one of Canada’s most illustrious surgeons in the second half of the 19th century. Not only was he a very innovative surgeon but he was an excellent teacher and wrote many medical articles during a career that spanned over 50 years. Active as he was medically, he found time to serve a term as mayor of Montreal and was on the board of directors of various banks and companies. As recognition of his many talents, he was knighted by Queen Victoria in 1895. He died in 1907 at the age of 78 years. PMID:8857994

  12. The Past, Present, and Future of Public Health Surveillance

    PubMed Central

    Choi, Bernard C. K.

    2012-01-01

    This paper provides a review of the past, present, and future of public health surveillance—the ongoing systematic collection, analysis, interpretation, and dissemination of health data for the planning, implementation, and evaluation of public health action. Public health surveillance dates back to the first recorded epidemic in 3180 B.C. in Egypt. Hippocrates (460 B.C.–370 B.C.) coined the terms endemic and epidemic, John Graunt (1620–1674) introduced systematic data analysis, Samuel Pepys (1633–1703) started epidemic field investigation, William Farr (1807–1883) founded the modern concept of surveillance, John Snow (1813–1858) linked data to intervention, and Alexander Langmuir (1910–1993) gave the first comprehensive definition of surveillance. Current theories, principles, and practice of public health surveillance are summarized. A number of surveillance dichotomies, such as epidemiologic surveillance versus public health surveillance, are described. Some future scenarios are presented, while current activities that can affect the future are summarized: exploring new frontiers; enhancing computer technology; improving epidemic investigations; improving data collection, analysis, dissemination, and use; building on lessons from the past; building capacity; enhancing global surveillance. It is concluded that learning from the past, reflecting on the present, and planning for the future can further enhance public health surveillance. PMID:24278752

  13. Sir William Osler revisited.

    PubMed Central

    Duffy, T. P.

    1980-01-01

    The basis of Sir William Osler's fame is elusive to almost all and the appropriateness of such recognition is questioned by many. His many contributions as a practitioner, teacher, writer, and scientist in medicine do not adequately explain his prominence 60 years following his death. It was his participation in the covenant of medicine and the special components of that relationship that may account for his hold on his followers today. Images FIG. 1 FIG. 2 PMID:6996344

  14. [Vascular malformations in the Williams-Beuren syndrome: report of three new cases].

    PubMed

    Sator, Hicham; Rhouni, Fatima Ezzahra; Benjouad, Ibitihale; Rhouni, Fatima Ezzahra; Benjouad, Ibitihale; Dafiri, Rachida; Chat, Latifa

    2016-01-01

    The Williams-Beuren syndrome is a rare genetic disease. It combines classically specific facial dysmorphism, cardiovascular malformations and specific neuropsychological profile. We report three cases of Williams-Beuren syndrome in children with particular emphasis on vascular abnormalities observed on CT angiography and MR angiography.

  15. 75 FR 22436 - Michael Williams-Control Exemption-St. Maries River Railroad, Inc.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-28

    ... DEPARTMENT OF TRANSPORTATION Surface Transportation Board [Docket No. FD 35365] Michael Williams-Control Exemption-St. Maries River Railroad, Inc. Michael Williams (applicant),\\1\\ a noncarrier, has filed a verified notice of exemption to acquire control of St. Maries River Railroad, Inc. (STMA), a Class...

  16. William Wolfgang Brickman, 1913-86.

    ERIC Educational Resources Information Center

    Parker, Franklin

    William Wolfgang Brickman, founding member and President, 1956-59, of the Comparative and International Education Society, died June 22, 1986, in a Philadelphia hospital leukemia unit. Born June 30, 1913, in New York City, he attended city schools and earned B.A. and M.S. degrees at City College, a New York University Ph.D. and an honorary M.A.…

  17. Stranger Danger Awareness in Williams Syndrome

    ERIC Educational Resources Information Center

    Riby, D. M.; Kirk, H.; Hanley, M.; Riby, L. M.

    2014-01-01

    Background: The developmental disorder Williams syndrome (WS) is characterised by a distinctive cognitive profile and an intriguing social phenotype. Individuals with the disorder are often highly social engaging with familiar and unfamiliar people and once in an interaction they often show subtle abnormalities of social behaviour. Atypically…

  18. 250 Years of Physics at the College of William and Mary: 1760-2010

    NASA Astrophysics Data System (ADS)

    von Baeyer, Hans

    2010-02-01

    The recorded history of physics at William and Mary begins when Thomas Jefferson, the College's most distinguished alumnus, meets his mentor, Dr. William Small of Scotland, who opens his eyes to the wonders of natural philosophy. After the vicissitudes of the Revolution and the Civil War, physics enjoys a revival in the twentieth century, culminating in the creation of a Ph.D. program in the 1960s and the building of the William Small Physical Laboratory in Williamsburg. In the 1980s the modern era is launched by the establishment of the US Department of Energy's Jefferson Lab for nuclear physics in nearby Newport News. Today both Small Hall and Jefferson Lab are in the process of renovation. The legacies of Small and Jefferson for physics at William and Mary are secure! )

  19. Musical learning in children and adults with Williams syndrome.

    PubMed

    Lense, M; Dykens, E

    2013-09-01

    There is recent interest in using music making as an empirically supported intervention for various neurodevelopmental disorders due to music's engagement of perceptual-motor mapping processes. However, little is known about music learning in populations with developmental disabilities. Williams syndrome (WS) is a neurodevelopmental genetic disorder whose characteristic auditory strengths and visual-spatial weaknesses map onto the processes used to learn to play a musical instrument. We identified correlates of novel musical instrument learning in WS by teaching 46 children and adults (7-49 years) with WS to play the Appalachian dulcimer. Obtained dulcimer skill was associated with prior musical abilities (r = 0.634, P < 0.001) and visual-motor integration abilities (r = 0.487, P = 0.001), but not age, gender, IQ, handedness, auditory sensitivities or musical interest/emotionality. Use of auditory learning strategies, but not visual or instructional strategies, predicted greater dulcimer skill beyond individual musical and visual-motor integration abilities (β = 0.285, sr(2) = 0.06, P = 0.019). These findings map onto behavioural and emerging neural evidence for greater auditory-motor mapping processes in WS. Results suggest that explicit awareness of task-specific learning approaches is important when learning a new skill. Implications for using music with populations with syndrome-specific strengths and weakness will be discussed. © 2012 The Authors. Journal of Intellectual Disability Research © 2012 John Wiley & Sons Ltd, MENCAP & IASSID.

  20. 33 CFR 164.43 - Automatic Identification System Shipborne Equipment-Prince William Sound.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Automatic Identification System Shipborne Equipment-Prince William Sound. 164.43 Section 164.43 Navigation and Navigable Waters COAST GUARD... Automatic Identification System Shipborne Equipment—Prince William Sound. (a) Until December 31, 2004, each...

  1. 33 CFR 164.43 - Automatic Identification System Shipborne Equipment-Prince William Sound.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false Automatic Identification System Shipborne Equipment-Prince William Sound. 164.43 Section 164.43 Navigation and Navigable Waters COAST GUARD... Automatic Identification System Shipborne Equipment—Prince William Sound. (a) Until December 31, 2004, each...

  2. 33 CFR 164.43 - Automatic Identification System Shipborne Equipment-Prince William Sound.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 2 2014-07-01 2014-07-01 false Automatic Identification System Shipborne Equipment-Prince William Sound. 164.43 Section 164.43 Navigation and Navigable Waters COAST GUARD... Automatic Identification System Shipborne Equipment—Prince William Sound. (a) Until December 31, 2004, each...

  3. N-acetylcysteine for neuropsychiatric symptoms in a woman with Williams syndrome.

    PubMed

    Pineiro, Mildred Lopez; Roberts, Antoinette M; Waxler, Jessica L; Mullett, Jennifer E; Pober, Barbara R; McDougle, Christopher J

    2014-11-01

    Williams syndrome is a relatively rare genetic disorder caused by the hemizygous microdeletion of a region in chromosome 7q11.23. Individuals with Williams syndrome typically present with a highly social, overfriendly, and empathic personality. Comorbid medical and neuropsychiatric disorders are common. Reports of effective pharmacological treatment of associated neuropsychiatric disorders are limited. The authors describe the successful treatment of interfering anger, aggression, and hair-pulling with N-acetylcysteine in a 19-year-old woman with Williams syndrome. The neuropsychiatric symptoms emerged 1 week following an upper gastrointestinal endoscopy, for which fentanyl, midazolam, and propofol were used as anesthetics. The patient's treatment course and hypothesized mechanisms underlying the clinical presentation and symptom resolution are described. © The Author(s) 2014.

  4. Williams receives a haircut from Yurchikhin in the SM during Expedition 15

    NASA Image and Video Library

    2007-06-03

    ISS015-E-10596 (3 June 2007) --- Cosmonaut Fyodor N. Yurchikhin, Expedition 15 commander representing Russia's Federal Space Agency, cuts astronaut Sunita L. Williams' hair in the Zvezda Service Module of the International Space Station. Williams, flight engineer, holds a vacuum device fashioned to garner freshly cut hair.

  5. Williams receives a haircut from Yurchikhin in the SM during Expedition 15

    NASA Image and Video Library

    2007-06-03

    ISS015-E-10595 (3 June 2007) --- Cosmonaut Fyodor N. Yurchikhin, Expedition 15 commander representing Russia's Federal Space Agency, cuts astronaut Sunita L. Williams' hair in the Zvezda Service Module of the International Space Station. Williams, flight engineer, holds a vacuum device fashioned to garner freshly cut hair.

  6. William E. Wilson and his contemporaries

    NASA Astrophysics Data System (ADS)

    Elliott, I.

    Although he never attended school or university, William E. Wilson FRS, of Daramona, County Westmeath, made pioneering contributions to solar physics, celestial photography and stellar photometry. His well-equipped observatory attracted collaborators who included George Francis FitzGerald of Trinity College Dublin and Arthur Rambaut of Dunsink Observatory.

  7. Fading-Figure Tracing in Williams Syndrome

    ERIC Educational Resources Information Center

    Nagai, Chiyoko; Inui, Toshio; Iwata, Makoto

    2011-01-01

    Williams syndrome (WS) is a neurodevelopmental disorder characterized by severe impairment of visuospatial abilities. Figure-drawing abilities, which are thought to reflect visuospatial abilities, have yet to be fully investigated in WS. The purpose of the present study was to clarify whether drawing abilities differ between WS individuals and…

  8. Using Authentic Literature to Develop Challenging and Integrated Curriculum

    ERIC Educational Resources Information Center

    Ciecierski, Lisa M.; Bintz, William P.

    2015-01-01

    Dr. William Alexander, a noted curriculum authority and a central founder of the middle school movement, shared in a presentation in 1963 that teachers must have a goal of stimulating a "love for learning, an attitude of inquiry, a passion for truth and beauty, a questioning of mind." He asserted, "Learning the right answers is not…

  9. Seasonal distribution of Dall's porpoise in Prince William Sound, Alaska

    NASA Astrophysics Data System (ADS)

    Moran, John R.; O'Dell, Matthew B.; Arimitsu, Mayumi L.; Straley, Janice M.; Dickson, Danielle M. S.

    2018-01-01

    Dall's porpoise, Phocoenoides dalli, are a conspicuous predator in the Prince William Sound ecosystem, yet there has been little effort directed towards monitoring this species since the 1980s, prior to the Exxon Valdez oil spill. We used vessel-based surveys to examine the seasonal distribution of Dall's porpoise in the waters of Prince William Sound during eight years from 2007 to 2015. Over the course of 168 days and 15,653 km of survey effort, 921 Dall's porpoise were encountered in 210 groups. We estimate an encounter rate of 0.061 porpoise/km traveled or 1 porpoise encountered for every 16.5 km traveled. Dall's porpoise were found throughout the year in Prince William Sound, and used a wide range of habitats, including those not considered typical of the species, such as bays, shallow water, and nearshore waters. Dall's porpoise seasonally shifted their center of distribution from the western passages in fall to the bays of the eastern Sound in winter and spring. Dall's porpoises were widely dispersed throughout the Sound in summer. We identified potential Dall's porpoise habitat (depth, slope, and distance from shore) within Prince William Sound using generalized additive models (GAM). Dall's porpoise were found in deeper water during summer and in shallowest water during spring. We propose that their use of novel habitats is a function of reduced predation risk associated with the decline of their main predator, killer whales (Orcinus orca), following the Exxon Valdez oil spill, and the presence of overwintering and spawning Pacific herring (Clupea pallasii). While the size of the Dall's porpoise population within Prince William Sound remains unknown, our encounter rates were lower than those reported in the 1970s. Their high metabolic rate and ubiquitous presence makes them one of the more important, yet understudied, forage fish predators in the region.

  10. Williams-Beuren syndrome associated with single kidney and nephrocalcinosis: a case report.

    PubMed

    Abidi, Kamel; Jellouli, Manel; Ben Rabeh, Rania; Hammi, Yousra; Gargah, Tahar

    2015-01-01

    Williams-Beuren syndrome is a rare neurodevelopmental disorder, characterized by congenital heart defects, abnormal facial features, mental retardation with specific cognitive and behavioral profile, growth hormone deficiency, renal and skeletal anomalies, inguinal hernia, infantile hypercalcaemia. We report a case with Williams-Beuren syndrome associated with a single kidney and nephrocalcinosis complicated by hypercalcaemia. A male infant, aged 20 months presented growth retardation associated with a psychomotor impairment, dysmorphic features and nephrocalcinosis. He had also hypercalciuria and hypercalcemia. Echocardiography was normal. DMSA renal scintigraphy showed a single functioning kidney. The FISH generated one ELN signal in 20 metaphases read and found the presence of ELN deletion, with compatible Williams-Beuren syndrome.

  11. ASK Talks with William Readdy

    NASA Technical Reports Server (NTRS)

    2004-01-01

    An interview with William Readdy is presented.Rsaddy graduated From the United States Naval Academy in 1974. After eleven years service as a naval aviator and test pilot, he joined NASA in 1986 as a research pilot. His technical assignments to date have included Training and Safety Officer, Orbiter project staff; NASA Director of Operations in Star City, Russia; and Space Shuttle Program Development Manager.

  12. Dr. Charles Alexander Eastman, Sioux Physician-Author, 1858-1939. With Teacher's Guide. Native Americans of the Twentieth Century.

    ERIC Educational Resources Information Center

    Minneapolis Public Schools, MN.

    A biography for elementary school students of a 19th century American Indian physician and author, Charles Alexander Eastman (Sioux), includes photographs of Dr. Eastman and his wife. A teacher's guide following the bibliography contains information on the Sioux Uprising of 1862 and the Wounded Knee Massacre, learning objectives and directions for…

  13. MRI Amygdala Volume in Williams Syndrome

    ERIC Educational Resources Information Center

    Capitao, Liliana; Sampaio, Adriana; Sampaio, Cassandra; Vasconcelos, Cristiana; Fernandez, Montse; Garayzabal, Elena; Shenton, Martha E.; Goncalves, Oscar F.

    2011-01-01

    One of the most intriguing characteristics of Williams Syndrome individuals is their hypersociability. The amygdala has been consistently implicated in the etiology of this social profile, particularly given its role in emotional and social behavior. This study examined amygdala volume and symmetry in WS individuals and in age and sex matched…

  14. Attention to Faces in Williams Syndrome

    ERIC Educational Resources Information Center

    Riby, Deborah M.; Jones, Nicola; Brown, Philippa H.; Robinson, Lucy J.; Langton, Stephen R. H.; Bruce, Vicki; Riby, Leigh M.

    2011-01-01

    Williams syndrome (WS) is associated with distinct social behaviours. One component of the WS social phenotype is atypically prolonged face fixation. This behaviour co-exists with attention difficulties. Attention is multi-faceted and may impact on gaze behaviour in several ways. Four experiments assessed (i) attention capture by faces, (ii)…

  15. A Conversation with William Van Til.

    ERIC Educational Resources Information Center

    Beineke, John A.

    1989-01-01

    Reports an interview with William Van Til, Coffman Distinguished Professor Emeritus of Education at Indiana State University (Terre Haute). Van Til reviews his career as a social studies teacher and his writings on curriculum and social foundations. Presents his opinions on progressive education, famous educators, educational history and reform,…

  16. William M. Harnett: "After the Hunt."

    ERIC Educational Resources Information Center

    Davidson, Edie

    1987-01-01

    Using William M. Harnett's 1884 oil painting "After the Hunt," this lesson introduces students in grades seven through nine to the style of realism popular in the late nineteenth century. The lesson is also designed to show how art reflects the values of the society in which it was created. (JDH)

  17. Brief Report: Repetitive Behaviour Profiles in Williams syndrome: Cross Syndrome Comparisons with Prader-Willi and Down syndromes.

    PubMed

    Royston, R; Oliver, C; Moss, J; Adams, D; Berg, K; Burbidge, C; Howlin, P; Nelson, L; Stinton, C; Waite, J

    2018-01-01

    This study describes the profile of repetitive behaviour in individuals with Williams syndrome, utilising cross-syndrome comparisons with people with Prader-Willi and Down syndromes. The Repetitive Behaviour Questionnaire was administered to caregivers of adults with Williams (n = 96), Prader-Willi (n = 103) and Down (n = 78) syndromes. There were few group differences, although participants with Williams syndrome were more likely to show body stereotypies. Individuals with Williams syndrome also showed more hoarding and less tidying behaviours than those with Down syndrome. IQ and adaptive ability were negatively associated with repetitive questioning in people with Williams syndrome. The profile of repetitive behaviour amongst individuals with Williams syndrome was similar to the comparison syndromes. The cognitive mechanisms underlying these behaviours in genetic syndromes warrant further investigation.

  18. What is the alternative to the Alexander-Orbach relation?

    NASA Astrophysics Data System (ADS)

    Sokolov, Igor M.

    2016-03-01

    The Alexander-Orbach (AO) relation d w = 2d f /d s connecting the fractal dimension of a random walk’s (RW) trajectory d w or the exponent of anomalous diffusion α = 2/d w on a fractal structure with the fractal and spectral dimension of the structure itself plays a key role in discussion of dynamical properties of complex systems including living cells and single biomolecules. This relation however does not hold universally and breaks down for some structures like diffusion limited aggregates and Eden trees. We show that the alternative to the AO relation is the explicit dependence of the coefficient of the anomalous diffusion on the system’s size, i.e. the absence of its thermodynamical limit. The prerequisite for its breakdown is the dependence of the local structure of possible steps of the RW on the system’s size. The discussion is illustrated by the examples of diffusion on a Koch curve (AO-conform) and on a Cantor dust (violating AO relation).

  19. Teaching Nuclear Radiation and the Poisoning of Alexander Litvinenko

    NASA Astrophysics Data System (ADS)

    Lapp, David R.

    2008-03-01

    The recent international story about the death of the former KGB agent Alexander Litvinenko has more than just a few wondering about radiation poisoning and the sinister sounding polonium-210. I was preparing to begin a nuclear radiation unit the Monday after Thanksgiving 2006. As it turned out, Litvinenko died Thanksgiving Day after a short and terrible three-week illness. Having the story continue to unfold throughout the next two weeks of the new unit provided a daily opportunity for students to see the relevance of what we were doing in class. My students were able to have meaningful and informed conversations with their peers and parents over an important international event. They even began to feel a bit like authorities themselves when listening to experts respond to media questions about polonium-210 and nuclear radiation in general. This paper discusses some of the ways that the story of Litvinenko was used while presenting the topic of nuclear radiation.

  20. Recent KBO (Pluto/Charon and beyond, including Quaoar) Occultation Observations by the Williams College Team as part of the Williams-MIT Collaboration

    NASA Astrophysics Data System (ADS)

    Pasachoff, Jay M.; Babcock, B. A.; Davis, A. B.; Pandey, S.; Lu, M.; Rogosinski, Z.; Person, M. J.; Bosh, A. S.; Zangari, A. M.; Zuluaga, C. A.; Gulbis, A. S.; Naranjo, O.; Navas, G.; Zerpa, L.; Villarreal, J.; Rojo, P.; Förster, F.; Servajean, E.

    2013-10-01

    The Williams College-MIT collaboration has observed numerous occultations of stars by Pluto/Charon and other Kuiper-belt objects (www.stellaroccultations.info), since its establishment three decades ago with an attempted discovery of Neptune's rings in 1983. In this paper, we describe several recent occultation observations, both successful and (for reasons of path uncertainties and/or weather) unsuccessful. Light curves made or arranged by Williams College faculty and students were used together with light curves by MIT colleagues and others to study Pluto's atmosphere and Charon's size, to discover one of the highest-known solar-system albedos (KBO 55636), and to attempt to study 1000-km-diameter Quaoar. Observations discussed include light curves for KBO 55636 on 9 October 2009 from Hawaii; Pluto on 3/4 July 2010 from Chile, 22 May 2011 from Williamstown, Massachusetts, 23 June 2011 from Hawaii (in support of SOFIA observations of Pluto's atmosphere, discussed in an article in press in AJ and of the pair of Pluto/Charon occultations of the same star), and 4 May 2013 (Bosh et al., this conference) and 15 July 2013 from Williamstown; Charon on 15 June 2013 from Williamstown; Quaoar from a picket fence ranging from Chile through Venezuela (with a detection there) to Massachusetts on July 8/9 and in South Africa on 12 July 2013. This work was supported in part by NASA Planetary Astronomy grants NNX08AO50G and NNH11ZDA001N to Williams College, NNX10AB27G to MIT, and USRA grant #8500-98-003 to Lowell Observatory. We thank Steven P. Souza at Williams; Steven Levine at Lowell Obs.; Jennifer G. Winters (GSU) in Chile; Richard Rojas/Jorge Moreno in Venezuela; Scott Sheppard; Federica Bianco; David Osip; and others. ZR (Vassar '14) was a Keck Northeast Astronomy Consortium Summer Fellow at Williams College, supported by an NSF/REU grant to the Keck Northeast Astronomy Consortium. ES: partial support from Programa Nacional de Becas de Postgrado (CONICYT Grant 21110496). FF

  1. Geophysicists

    NASA Astrophysics Data System (ADS)

    2004-02-01

    In Memoriam: Francis R. ``Joe'' Boyd, John B. Ivey, William Warren Kellogg, Norma N. McMillin, Henry T. R. Radoski, William (Bill) Sackett, John W. Sherman, III, Kjell Petter Skjerlie, Peter Bernard Smoor; Recent Ph.D.s: Joan Bech, Mark Pickett

  2. Foreword: Sir John Pendry FRS Sir John Pendry FRS

    NASA Astrophysics Data System (ADS)

    Inglesfield, John; Echenique, Pedro

    2008-07-01

    John Pendry John Inglesfield and Pedro Echenique write: John Pendry's 65th birthday is on 4 July 2008, and this issue of the Journal of Physics: Condensed Matter is dedicated to him, with articles by friends, colleagues, and former students. By any standards, John Pendry is a great scientist, who has made—and continues to make—an enormous contribution to physics; the wide range of his interests is reflected in the scope of these articles. Not many scientists can establish a completely new and unexpected area of research, but this has been John's achievement in the last few years in the field of metamaterials, materials whose electromagnetic properties depend on their structure rather than the materials of which the structure is built. In this way, structures with effectively negative electrical permittivity and negative magnetic permeability can be constructed, demonstrating negative refraction; through metamaterials scientists now have access to properties not found in nature, and never previously explored experimentally. Never a week goes by without a potential new application of metamaterials, whether it is perfect lensing, or the cloak of invisibility. This has certainly led to tremendous visibility for John himself, with guest lectures all over the world, and radio and television appearances. John Pendry's first paper was published exactly 40 years ago, 'Analytic properties of pseudopotentials' [1], and since then he has published 310 articles at the latest count. But this first paper already reflected something of the way John works. His PhD project, with Volker Heine at the Cavendish Laboratory, was to interpret the scattering of low energy electrons from surfaces, the technique of LEED which was to become the method of choice for determining surface structure. Although the energy of the electrons in LEED is relatively low—say 50 eV—it is much higher than the energy of the conduction electrons, for which pseudopotentials had been devised, and John

  3. Alexander fractional differential window filter for ECG denoising.

    PubMed

    Verma, Atul Kumar; Saini, Indu; Saini, Barjinder Singh

    2018-06-01

    The electrocardiogram (ECG) non-invasively monitors the electrical activities of the heart. During the process of recording and transmission, ECG signals are often corrupted by various types of noises. Minimizations of these noises facilitate accurate detection of various anomalies. In the present paper, Alexander fractional differential window (AFDW) filter is proposed for ECG signal denoising. The designed filter is based on the concept of generalized Alexander polynomial and the R-L differential equation of fractional calculus. This concept is utilized to formulate a window that acts as a forward filter. Thereafter, the backward filter is constructed by reversing the coefficients of the forward filter. The proposed AFDW filter is then obtained by averaging of the forward and backward filter coefficients. The performance of the designed AFDW filter is validated by adding the various type of noise to the original ECG signal obtained from MIT-BIH arrhythmia database. The two non-diagnostic measure, i.e., SNR, MSE, and one diagnostic measure, i.e., wavelet energy based diagnostic distortion (WEDD) have been employed for the quantitative evaluation of the designed filter. Extensive experimentations on all the 48-records of MIT-BIH arrhythmia database resulted in average SNR of 22.014 ± 3.806365, 14.703 ± 3.790275, 13.3183 ± 3.748230; average MSE of 0.001458 ± 0.00028, 0.0078 ± 0.000319, 0.01061 ± 0.000472; and average WEDD value of 0.020169 ± 0.01306, 0.1207 ± 0.061272, 0.1432 ± 0.073588, for ECG signal contaminated by the power line, random, and the white Gaussian noise respectively. A new metric named as morphological power preservation measure (MPPM) is also proposed that account for the power preservance (as indicated by PSD plots) and the QRS morphology. The proposed AFDW filter retained much of the original (clean) signal power without any significant morphological distortion as validated by MPPM measure that were 0

  4. The Pennsylvania Anatomy Act of 1883: Weighing the Roles of Professor William Smith Forbes and Senator William James McKnight.

    PubMed

    Wright, James R

    2016-10-01

    Effective Anatomical Acts transformed medical education and curtailed grave-robbing. William S. Forbes, Demonstrator of Anatomy at Jefferson Medical College in Philadelphia, authored the Pennsylvania Anatomy Act of 1867, but it was ineffective. In December of 1882, Forbes and accomplices were charged with grave-robbing. Forbes was acquitted in early 1883, but his accomplices were all convicted; nevertheless, these events precipitated a strengthened Anatomy Act in 1883. Forbes was crowned the Father of the Pennsylvania Anatomy Act and was revered by the Philadelphia medical community for his personal sacrifices for medical education; they even paid his legal fees. Over the remainder of his life, Forbes received many honors. However, there was a second major player, rural doctor William J. McKnight, a convicted grave-robber and State Senator. The evidence shows that Forbes precipitated the crisis, which was a racial powder keg, and then primarily focused on his trial, while McKnight, creatively working behind the scenes in collaboration with Jefferson, Anatomy Professor William H. Pancoast, used the crisis to draft and pass transformative legislation enabling anatomical dissection at Pennsylvania medical schools. While not minimizing Forbes suffering throughout these events, McKnight should be appropriately recognized for his initiative and contributions, which far exceeded those of Forbes. © The Author 2016. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  5. Outcome in Adult Life for People with Williams Syndrome Results from a Survey of 239 Families

    ERIC Educational Resources Information Center

    Howlin, P.; Udwin, O.

    2006-01-01

    BACKGROUND: Although there has been considerable research into the genotype and phenotype of Williams syndrome, there have been relatively few studies of long-term prognosis. As a preliminary to a more detailed investigation of adults with Williams syndrome, a parental questionnaire was distributed to members of the UK Williams Syndrome…

  6. Coronary ostium occlusion by coronary cusp displacement in Williams syndrome.

    PubMed

    Shiohama, Tadashi; Fujii, Katsunori; Ebata, Ryota; Funabashi, Nobusada; Matsumiya, Goro; Saito, Yuko Kazato; Takechi, Fumie; Yonemori, Yoko; Nakatani, Yukio; Shimojo, Naoki

    2016-06-01

    Williams syndrome is a contiguous gene deletion syndrome resulting from a heterozygous deletion on chromosome 7q11.23, and is characterized by distinctive facial features and supravalvular aortic stenosis (SVAS). This syndrome rarely presents unpredictable cardiac death, and yet, as illustrated in the present case, it is still not possible to predict it, even on close monitoring. We herein describe the case of a 6-year-old Japanese girl with Williams syndrome, who had sudden cardiac collapse due to cardiac infarction after pharyngitis. Cardiac failure followed a critical course that did not respond to catecholamine support or heart rest with extracardiac mechanical support. Although marked coronary stenosis was not present, the left coronary cusp abnormally adhered to the aortic wall, which may synergistically cause coronary ostium occlusion with SVAS. Altered hemodynamic state, even that caused by the common cold, may lead to critical myocardial events in Williams syndrome with SVAS. © 2015 Japan Pediatric Society.

  7. St. John's Wort (image)

    MedlinePlus

    The herb St. John's Wort is believed to be helpful in relieving mild to moderate depression, but should only be taken under a physician's supervision. St. John's Wort may clash with other medications or ...

  8. False belief attribution in children with Williams syndrome: the answer is in the emotion.

    PubMed

    Campos, R; Martínez-Castilla, P; Sotillo, M

    2017-11-01

    Individuals with Williams syndrome (WS) show difficulties in attributing false beliefs, whereas they are better at attributing emotions. This study examines whether being asked about the emotion linked to a false belief, instead of explicitly about the belief, facilitates performance on theory of mind (ToM) tasks. Thirty children with WS and 90 typically developing children, who were individually matched on mental age (50-112 months), were administered six explicit (i.e. questions on belief) and six implicit (i.e. questions on emotion) trials of false belief tasks. Theory of mind competences were related to cognitive development. Children with WS performed comparably to typically developing children on the emotion questions. Correct answers to questions on emotion reveal an implicit understanding of false belief. The Representational redescription process could be impaired in the domain of ToM in this population. This finding has relevant implications for the design of supports aiming to optimise the development of ToM competences in individuals with WS. © 2017 MENCAP and International Association of the Scientific Study of Intellectual and Developmental Disabilities and John Wiley & Sons Ltd.

  9. Mythorealistic Concept of "Beautiful Lady" in the Structure of the Author's Identity (Based on the Diaries of Alexander Blok)

    ERIC Educational Resources Information Center

    Minets, Diana

    2016-01-01

    The present paper deals with the diaries of Alexander Blok dated 1901-1921 reflecting the process of the writer's self-identification. During 20 years under the influence of various social and cultural situations Blok's "Self-Conception" is undergoing significant changes. The vector of these changes shows the complicated evolution of the…

  10. On the Social Psychology of Higher Education: A Bibliography of Alexander W. Astin. Public Administration Series Bibliography, P-688.

    ERIC Educational Resources Information Center

    Quay, Richard H.

    A bibliography of articles by Alexander W. Astin on the social psychology of higher education is presented. Entries are presented by year, starting with 1980 and dating back to 1956. Topics that are covered include: equal access to higher education, student persistence and attrition, higher education policy, selective admissions and open…

  11. Holocene deposition and megathrust splay fault geometries within Prince William Sound, Alaska

    NASA Astrophysics Data System (ADS)

    Finn, S.; Liberty, L. M.; Haeussler, P. J.; Pratt, T. L.

    2011-12-01

    New high resolution sparker seismic reflection data, in conjunction with reprocessed legacy seismic data, provide the basis for a new fault, fold, and Holocene sediment thickness database for Prince William Sound, Alaska. Additionally, legacy airgun seismic data in Prince William Sound and the Gulf of Alaska tie features on these new sparker data to deeper portions of megathrust splay faults. We correlate regionally extensive bathymetric lineaments within Prince William Sound to megathrust splay faults, such as the ones that ruptured in the 1964 M9.2 earthquake. Lastly, we estimate Holocene sediment thickness within Prince William Sound to better constrain the Holocene fault history throughout the region. We identify three seismic facies related to Holocene, Quaternary, and Tertiary strata that are crosscut by numerous high angle normal faults in the hanging wall of the megathrust splay faults. The crustal-scale seismic reflection profiles show splay faults emerging from 20 km depth between the Yakutat block and North American crust and surfacing as the Hanning Bay and Patton Bay faults. A change in exhumation rates, slip rates, and fault orientation appears near Hinchinbrook that we attribute to differences in subducted slab geometry. Based on our slip rate analysis, we calculate average Holocene displacements of 20 m and 100 m in eastern and western Prince William Sound, respectively. Landward of two splay faults exposed on Montague Island, we observe subsidence, faulting, and landslides that record deformation associated with the 1964 and older megathrust earthquakes.

  12. Attentional Disengagement in Adults with Williams Syndrome

    ERIC Educational Resources Information Center

    Lense, Miriam D.; Key, Alexandra P.; Dykens, Elisabeth M.

    2011-01-01

    Williams syndrome (WS) is a neurodevelopmental disorder characterized by a distinctive behavioral and cognitive profile, including widespread problems with attention. However, the specific nature of their attentional difficulties, such as inappropriate attentional allocation and/or poor attentional disengagement abilities, has yet to be…

  13. Sleep-EEG in dizygotic twins discordant for Williams syndrome.

    PubMed

    Bódizs, Róbert; Gombos, Ferenc; Szocs, Katalin; Réthelyi, János M; Gerván, Patrícia; Kovács, Ilona

    2014-01-30

    Reports on twin pairs concordant and discordant for Williams syndrome were published before, but no study unravelled sleep physiology in these cases yet. We aim to fill this gap by analyzing sleep records of a twin pair discordant for Williams syndrome extending our focus on presleep wakefulness and sleep spindling. We performed multiplex ligation-dependent probe amplification of the 7q11.23 region of a 17 years old dizygotic opposite-sex twin pair discordant for Williams syndrome. Polysomnography of laboratory sleep at this age was analyzed and followed-up after 1.5 years by ambulatory polysomnography. Sleep stages scoring, EEG power spectra and sleep spindle analyses were carried out. The twin brother showed reduced levels of amplification for all of the probes in the 7q11.23 region indicating a typical deletion spanning at least 1.038 Mb between FKBP6 and CLIP2. The results of the twin sister showed normal copy numbers in the investigated region. Lower sleep times and efficiencies, as well as higher slow wave sleep percents of the twin brother were evident during both recordings. Roughly equal NREM, Stage 2 and REM sleep percents were found. EEG analyses revealed state and derivation-independent decreases in alpha power, lack of an alpha spectral peak in presleep wakefulness, as well as higher NREM sleep sigma peak frequency in the twin brother. Faster sleep spindles with lower amplitude and shorter duration characterized the records of the twin brother. Spectra show a striking reliability and correspondence between the two situations (laboratory vs. home records). Alterations in sleep and specific neural oscillations including the alpha/sigma waves are inherent aspects of Williams syndrome.

  14. Comparison of the CEAS and Williams-type barley yield models for North Dakota and Minnesota

    NASA Technical Reports Server (NTRS)

    Leduc, S. (Principal Investigator)

    1982-01-01

    The CEAS and Williams type models were compared based on specified selection criteria which includes a ten year bootstrap test (1970-1979). Based on this, the models were quite comparable; however, the CEAS model was slightly better overall. The Williams type model seemed better for the 1974 estimates. Because that year spring wheat yield was particularly low, the Williams type model should not be excluded from further consideration.

  15. Auditory Attraction: Activation of Visual Cortex by Music and Sound in Williams Syndrome

    ERIC Educational Resources Information Center

    Thornton-Wells, Tricia A.; Cannistraci, Christopher J.; Anderson, Adam W.; Kim, Chai-Youn; Eapen, Mariam; Gore, John C.; Blake, Randolph; Dykens, Elisabeth M.

    2010-01-01

    Williams syndrome is a genetic neurodevelopmental disorder with a distinctive phenotype, including cognitive-linguistic features, nonsocial anxiety, and a strong attraction to music. We performed functional MRI studies examining brain responses to musical and other types of auditory stimuli in young adults with Williams syndrome and typically…

  16. WILLIAM GOLDING'S NOVEL--THE BACKWARD LOOK.

    ERIC Educational Resources Information Center

    PECK, CAROL FAULKNER

    THE "SURPRISE ENDINGS" IN EACH OF WILLIAM GOLDING'S FIRST FOUR NOVELS OCCUR WHEN THE POINT OF VIEW SHIFTS FROM THE LIMITED WORLD OF THE NOVEL TO THE UNLIMITED WORLD OF REALITY. THE BOYS' RESCUE BY THE UNCOMPREHENDING OFFICER IN "LORD OF THE FLIES," REFOCUSES AND REINFORCES ALL THAT PRECEDES IT, AND THE FABLE, SUPERIMPOSED UPON REAL LIFE, BECOMES…

  17. Jasper Johns' Painted Words.

    ERIC Educational Resources Information Center

    Levinger, Esther

    1989-01-01

    States that the painted words in Jasper Johns' art act in two different capacities: concealed words partake in the artist's interrogation of visual perception; and visible painted words question classical representation. Argues that words are Johns' means of critiquing modernism. (RS)

  18. Feasibility of an Extended-Duration Aerial Platform Using Autonomous Multi-Rotor Vehicle Swapping and Battery Management

    DTIC Science & Technology

    2017-12-01

    AN EXTENDED-DURATION AERIAL PLATFORM USING AUTONOMOUS MULTI-ROTOR VEHICLE SWAPPING AND BATTERY MANAGEMENT by Alexander G. Williams December...Approved OMB No. 0704-0188 Public reporting burden for this collection of information is estimated to average 1 hour per response, including the time...of information . Send comments regarding this burden estimate or any other aspect of this collection of information , including suggestions for

  19. 5. DETAIL OF BUILDER'S PLATE, WHICH READS '1898, THE SANITARY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. DETAIL OF BUILDER'S PLATE, WHICH READS '1898, THE SANITARY DISTRICT OF CHICAGO, BOARD OF TRUSTEES, WILLIAM BOLDENWECK, JOSEPH C. BRADEN, ZINA R. CARTER, BERNARD A. ECKART, ALEXANDER J. JONES, THOMAS KELLY, JAMES P. MALLETTE, THOMAS SMYTHE, FRANK WINTER; ISHAM RANDOLPH, CHIEF ENGINEER.' - Santa Fe Railroad, Sanitary & Ship Canal Bridge, Spanning Sanitary & Ship Canal east of Harlem Avenue, Chicago, Cook County, IL

  20. Williams with VO2max

    NASA Image and Video Library

    2012-08-08

    ISS032-E-016876 (8 Aug. 2012) --- NASA astronaut Sunita Williams, Expedition 32 flight engineer, performs a VO2max experiment while using the Cycle Ergometer with Vibration Isolation System (CEVIS) in the Destiny laboratory of the International Space Station. VO2max uses the Portable Pulmonary Function System (PPFS), CEVIS, Pulmonary Function System (PFS) gas cylinders and mixing bag system, plus multiple other pieces of hardware to measure oxygen uptake and cardiac output.

  1. A TRIBUTE TO DR. WILLIAM PENN WATKINSON

    EPA Science Inventory

    Dr. William Penn Watkinson (known to colleagues as "Penn") of EPA¿s health research lab (National Health and Environmental Research Laboratory) of Research Triangle Park, North Carolina, died Wednesday, December 13 after a battle with lung cancer. He was a member of the Pulmonar...

  2. SHUTTLE - ASTRONAUT-CANDIDATE (ASCAN) WILLIAMS, DONALD (DON)

    NASA Image and Video Library

    1979-04-03

    S79-30367/69: Exterior views of 747 Shuttle Aircraft. S79-30360/66: ASCAN Don Williams during H Reflex Studies and Hamilton-Standard Tool Belt and Suit Cooling System Tests. 1. AIRCRAFT - 747 2. SHUTTLE - TESTS. S79-30360 thru S79-30369

  3. Parent and teacher perspectives about problem behavior in children with Williams syndrome.

    PubMed

    Klein-Tasman, Bonita P; Lira, Ernesto N; Li-Barber, Kirsten T; Gallo, Frank J; Brei, Natalie G

    2015-01-01

    Problem behavior of 52 children with Williams syndrome ages 6 to 17 years old was examined based on both parent and teacher report. Generally good inter-rater agreement was found. Common areas of problem behavior based both on parent and teacher report included attention problems, anxiety difficulties, repetitive behaviors (e.g., obsessions, compulsions, picking nose or skin), and social problems, reflecting a robust behavioral phenotype in Williams syndrome present across contexts. Some rater differences were observed; most notably, parents reported more attention and mood difficulties than did teachers, while teachers reported more oppositionality and aggression than did parents. Relations to intellectual functioning, age, and gender were examined. The implications of the findings for understanding the behavioral phenotype associated with Williams syndrome are discussed.

  4. Expedition 21 astronauts Jeff Williams and Nicole Stott

    NASA Image and Video Library

    2009-06-24

    Date: 6-24-09 Location: Bldg 9NW - Node 1 Training Area Subject: Expedition 21 astronauts Jeff Williams and Nicole Scott during new Vestibule Procedures training with instructor Michael Steele. Photographer: Lauren Harnett

  5. Silurian trace fossils in carbonate turbidites from the Alexander Arc of southeastern Alaska

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Soja, C.M.

    Early to Late Silurian (Wenlock-Ludlow) body and trace fossils from the Heceta Formation are preserved in the oldest widespread carbonates in the Alexander terrane of southeastern Alaska. They represent the earliest shelly benthos to inhabit a diversity of marine environments and are important indicators of the early stages in benthic community development within this ancient island arc. The trace fossils are significant because they add to a small but growing body of knowledge about ichnofaunas in deep-water Paleozoic carbonates. Proximal to medial carbonate turbidites yield a low-diversity suite of trace fossils that comprises five distinct types of biogenic structures. Beddingmore » planes reveal simple epichnial burrows (Planolites), cross-cutting burrows (Fucusopsis), and tiny cylindrical burrows. These and other casts, including chondrites( )-like burrow clusters, represent the feeding activities (fodinichnia) of preturbidite animals. Hypichnial burrows and rare endichnial traces reflect the activities of postturbidite animals. Broken and offset traces indicate that infaunal biota commenced burrowing before slumping and subsequent soft-sediment deformation. The abundance and density of trace fossils increases offshore in the medial turbidites associated with a decrease in the size and amount of coarse particles and with an increase in mud and preserved organic material. Although diversity levels are similar in the proximal and medial turbidite facies, they are much lower than in Paleozoic siliciclastic turbidites. This may reflect unfavorable environmental conditions for infaunal biota or paleobiogeographic isolation of the Alexander terrane during the Silurian. A greater use of trace fossils in terrane analysis will help to resolve this issue and should provide new data for reconstructing the paleogeography of circum-Pacific terranes.« less

  6. 78 FR 71022 - Culturally Significant Objects Imported for Exhibition Determinations: “Christopher Williams: The...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-27

    ... DEPARTMENT OF STATE [Public Notice 8537] Culturally Significant Objects Imported for Exhibition Determinations: ``Christopher Williams: The Production Line of Happiness'' SUMMARY: Notice is hereby given of the... exhibition ``Christopher Williams: The Product Line of Happiness,'' imported from abroad for temporary...

  7. Robert Owen, William Maclure and New Harmony.

    ERIC Educational Resources Information Center

    Mclaren, David J.

    1996-01-01

    Discusses the utopian philosophy and related educational practices of the early 19th-century communitarian settlement in New Harmony, Indiana. The settlement failed after several years, due in no small part to the falling out between its two main supporters, Robert Owen and William Maclure. (MJP)

  8. Tyurin and Williams in Zvezda Service module

    NASA Image and Video Library

    2007-04-21

    ISS014-E-19924 (21 April 2007) --- Cosmonaut Mikhail Tyurin (left), Expedition 14 flight engineer representing Russia's Federal Space Agency, and astronaut Sunita L. Williams, Expedition 15 flight engineer, drink beverages as they pose for a photo in the Zvezda Service Module of the International Space Station.

  9. Maria Montessori, John Dewey, and William H. Kilpatrick

    ERIC Educational Resources Information Center

    Thayer-Bacon, Barbara

    2012-01-01

    I explore Montessori's story in terms of her initial warm reception by America to her educational research, and her later cooling off, once Dewey's student, Kilpatrick, published The Montessori System Examined and declared her work to be based on psychological theory that was fifty years behind the times. I argue that there is a troubling gendered…

  10. Colour discrimination and categorisation in Williams syndrome.

    PubMed

    Farran, Emily K; Cranwell, Matthew B; Alvarez, James; Franklin, Anna

    2013-10-01

    Individuals with Williams syndrome (WS) present with impaired functioning of the dorsal visual stream relative to the ventral visual stream. As such, little attention has been given to ventral stream functions in WS. We investigated colour processing, a predominantly ventral stream function, for the first time in nineteen individuals with Williams syndrome. Colour discrimination was assessed using the Farnsworth-Munsell 100 hue test. Colour categorisation was assessed using a match-to-sample test and a colour naming task. A visual search task was also included as a measure of sensitivity to the size of perceptual colour difference. Results showed that individuals with WS have reduced colour discrimination relative to typically developing participants matched for chronological age; performance was commensurate with a typically developing group matched for non-verbal ability. In contrast, categorisation was typical in WS, although there was some evidence that sensitivity to the size of perceptual colour differences was reduced in this group. Copyright © 2013 Elsevier Ltd. All rights reserved.

  11. Williams with TRAC experiment in Destiny

    NASA Image and Video Library

    2007-03-08

    ISS014-E-16215 (8 March 2007) --- Astronaut Sunita L. Williams, Expedition 14 flight engineer, works with the Test of Reaction and Adaptation Capabilities (TRAC) experiment in the Destiny laboratory of the International Space Station. The TRAC investigation will test the theory of brain adaptation during space flight by testing hand-eye coordination before, during and after the space flight.

  12. Williams with TRAC experiment in Destiny

    NASA Image and Video Library

    2007-03-08

    ISS014-E-16210 (8 March 2007) --- Astronaut Sunita L. Williams, Expedition 14 flight engineer, works with the Test of Reaction and Adaptation Capabilities (TRAC) experiment in the Destiny laboratory of the International Space Station. The TRAC investigation will test the theory of brain adaptation during space flight by testing hand-eye coordination before, during and after the space flight.

  13. Williams with TRAC experiment in Destiny

    NASA Image and Video Library

    2007-03-08

    ISS014-E-16214 (8 March 2007) --- Astronaut Sunita L. Williams, Expedition 14 flight engineer, works with the Test of Reaction and Adaptation Capabilities (TRAC) experiment in the Destiny laboratory of the International Space Station. The TRAC investigation will test the theory of brain adaptation during space flight by testing hand-eye coordination before, during and after the space flight.

  14. Bokan Mountain peralkaline granitic complex, Alexander terrane (southeastern Alaska): evidence for Early Jurassic rifting prior to accretion with North America

    USGS Publications Warehouse

    Dostal, Jaroslav; Karl, Susan M.; Keppie, J. Duncan; Kontak, Daniel J.; Shellnutt, J. Gregory

    2013-01-01

    The circular Bokan Mountain complex (BMC) on southern Prince of Wales Island, southernmost Alaska, is a Jurassic peralkaline granitic intrusion about 3 km in diameter that crosscuts igneous and metasedimentary rocks of the Alexander terrane. The BMC hosts significant rare metal (rare earth elements, Y, U, Th, Zr, and Nb) mineralization related to the last stage of BMC emplacement. U–Pb (zircon) and 40Ar/39Ar (amphibole and whole-rock) geochronology indicates the following sequence of intrusive activity: (i) a Paleozoic basement composed mainly of 469 ± 4 Ma granitic rocks; (ii) intrusion of the BMC at 177 ± 1 Ma followed by rapid cooling through ca. 550 °C at 176 ± 1 Ma that was synchronous with mineralization associated with vertical, WNW-trending pegmatites, felsic dikes, and aegirine–fluorite veins and late-stage, sinistral shear deformation; and (iii) intrusion of crosscutting lamprophyre dikes at >150 Ma and again at ca. 105 Ma. The peralkaline nature of the BMC and the WNW trend of associated dikes suggest intrusion during NE–SW rifting that was followed by NE–SW shortening during the waning stages of BMC emplacement. The 177 Ma BMC was synchronous with other magmatic centres in the Alexander terrane, such as (1) the Dora Bay peralkaline stock and (2) the bimodal Moffatt volcanic suite located ∼30 km north and ∼100 km SE of the BMC, respectively. This regional magmatism is interpreted to represent a regional extensional event that precedes deposition of the Late Jurassic – Cretaceous Gravina sequence that oversteps the Wrangellia and Alexander exotic accreted terranes and the Taku and Yukon–Tanana pericratonic terranes of the Canadian–Alaskan Cordillera.

  15. Bokan Mountain peralkaline granitic complex, Alexander terrane (southeastern Alaska): evidence for Early Jurassic rifting prior to accretion with North America

    USGS Publications Warehouse

    Dostal, Jaroslav; Karl, Susan M.; Keppie, J. Duncan; Kontak, Daniel J.; Shellnutt, J. Gregory

    2013-01-01

    The circular Bokan Mountain complex (BMC) on southern Prince of Wales Island, southernmost Alaska, is a Jurassic peralkaline granitic intrusion about 3 km in diameter that crosscuts igneous and metasedimentary rocks of the Alexander terrane. The BMC hosts significant rare metal (rare earth elements, Y, U, Th, Zr, and Nb) mineralization related to the last stage of BMC emplacement. U–Pb (zircon) and 40Ar/39Ar (amphibole and whole-rock) geochronology indicates the following sequence of intrusive activity: (i) a Paleozoic basement composed mainly of 469 ± 4 Ma granitic rocks; (ii) intrusion of the BMC at 177 ± 1 Ma followed by rapid cooling through ca. 550 °C at 176 ± 1 Ma that was synchronous with mineralization associated with vertical, WNW-trending pegmatites, felsic dikes, and aegirine–fluorite veins and late-stage, sinistral shear deformation; and (iii) intrusion of crosscutting lamprophyre dikes at >150 Ma and again at ca. 105 Ma. The peralkaline nature of the BMC and the WNW trend of associated dikes suggest intrusion during NE–SW rifting that was followed by NE–SW shortening during the waning stages of BMC emplacement. The 177 Ma BMC was synchronous with other magmatic centres in the Alexander terrane, such as (1) the Dora Bay peralkaline stock and (2) the bimodal Moffatt volcanic suite located ~30 km north and ~100 km SE of the BMC, respectively. This regional magmatism is interpreted to represent a regional extensional event that precedes deposition of the Late Jurassic – Cretaceous Gravina sequence that oversteps the Wrangellia and Alexander exotic accreted terranes and the Taku and Yukon–Tanana pericratonic terranes of the Canadian–Alaskan Cordillera.

  16. Possible refugia in the Alexander Archipelago of southeastern Alaska during the late Wisconsin glaciation

    USGS Publications Warehouse

    Carrara, P.E.; Ager, T.A.; Baichtal, J.F.

    2007-01-01

    The interpretation of the extent of late Wisconsin glaciation in southeastern Alaska has varied between geologists and biologists. Maps and reports of the region prepared by geologists commonly indicated that late Wisconsin ice extended as a large uniform front west to the edge of the continental shelf. However, the distribution of plants and animals in the region has led many biologists to suggest that there may have been ice-free areas that served as refugia during the late Wisconsin. Based on analyses of aerial photographs, topographic maps, and bathymetric charts, in conjunction with a review of previous literature and reconnaissance fieldwork throughout the region, this study presents data supporting a limited ice extent in the Alexander Archipelago during the late Wisconsin and identifies possible ice-free areas that may have served as refugia. These areas include (1) the Fairweather Ground, (2) the Herbert Graves Island area, (3) the western coast of southern Baranof Island and adjacent continental shelf, (4) Coronation Island and the adjacent continental shelf, (5) the Warren Island area, (6) the continental shelf from west of Heceta Island to Forrester Island in the south, (7) parts of the west coast of southern Dall Island, and (8) lowland areas in southern Prince of Wales Island. The identification of these possible refugia has bearing on the recolonization of the Alexander Archipelago, as they could have served as centers of biotic dispersal upon regional deglaciation and as stepping stones for early humans with a maritime tradition entering the western hemisphere from Asia. ?? 2007 NRC Canada.

  17. Attribution of Negative Intention in Williams Syndrome

    ERIC Educational Resources Information Center

    Godbee, Kali; Porter, Melanie A.

    2013-01-01

    People with Williams syndrome (WS) are said to have sociable and extremely trusting personalities, approaching strangers without hesitation. This study investigated whether people with WS are less likely than controls to attribute negative intent to others when interpreting a series of ambiguous pictures. This may, at least partially, explain…

  18. Executive Function in Williams and Down Syndromes

    ERIC Educational Resources Information Center

    Carney, Daniel P. J.; Brown, Janice H.; Henry, Lucy A.

    2013-01-01

    Williams (WS) and Down (DS) syndromes are characterised by roughly opposing ability profiles. Relative verbal strengths and visuospatial difficulties have been reported in those with WS, while expressive language difficulties have been observed in individuals with DS. Few investigations into the executive function (EF) skills of these groups have…

  19. Analysis of Speech Fluency in Williams Syndrome

    ERIC Educational Resources Information Center

    Rossi, Natalia Freitas; Sampaio, Adriana; Goncalves, Oscar F.; Giacheti, Celia Maria

    2011-01-01

    Williams syndrome (WS) is a neurodevelopmental genetic disorder, often referred as being characterized by dissociation between verbal and non-verbal abilities, although the number of studies disputing this proposal is emerging. Indeed, although they have been traditionally reported as displaying increased speech fluency, this topic has not been…

  20. Pittu Laungani in Conversation with William West

    ERIC Educational Resources Information Center

    Chantler, Khatidja

    2006-01-01

    In this response to Pittu Laungani's conversation with William West, published in the August, 2004, issue of "British Journal of Guidance and Counselling," the author questions why person-centred counselling has been singled out for particular attention, argues that the dichotomy between client-centred and culture-centred counselling is…

  1. Understanding Williams Syndrome: Behavioral Patterns and Interventions.

    ERIC Educational Resources Information Center

    Semel, Eleanor; Rosner, Sue R.

    This guide to Williams syndrome (WS), a congenital disorder characterized by developmental/cognitive limitations but relatively high verbal and social skills, explains the strengths, difficulties and variations found among individuals with the condition and offers guidelines for intervention in the unusual properties of the WS behavioral profile.…

  2. Problem behaviour and psychosocial functioning in young children with Williams syndrome: parent and teacher perspectives.

    PubMed

    Klein-Tasman, B P; Lee, K

    2017-09-01

    There is sparse literature about problem behaviour in young children with Williams syndrome (WS) and little consideration of the perspectives of multiple respondents. Problem behaviour of 35 children with WS ages 2 to 6 was examined based on both parent and teacher report using the Achenbach preschool forms. The most prominent areas of difficulty based on both parent and teacher report were attention problems, pervasive developmental problems and emotion reactivity difficulties. Some rater differences were observed; most notably, teachers reported more externalising behaviour problems including more aggressive behaviour, Attention Deficit/Hyperactivity problems and Oppositional Defiant problems than did parents. Few relations to intellectual functioning, age or gender were observed. Some aspects of problem behaviour evident in older children (e.g. attention problems, social problems) are also apparent for young children with WS, while other areas are less prominent (e.g. anxiety). The implications of the findings for understanding the behavioural phenotype associated with WS are discussed. © 2017 MENCAP and International Association of the Scientific Study of Intellectual and Developmental Disabilities and John Wiley & Sons Ltd.

  3. William Barlow and the Determination of Atomic Arrangement in Crystals.

    PubMed

    Mauskopf, Seymour H

    2015-04-01

    William Barlow (1845-1934) was an important if unconventional scientist, known for having developed the 'closest-packing' atomic models of crystal structure. He resumed an early nineteenth-century tradition of utilizing crystallographical and chemical data to determine atomic arrangements in crystals. This essay recounts Barlow's career and scientific activity in three parts: (a) His place in the tradition of determining atomic arrangement in context of this earlier tradition and of contemporaneous developments of crystallography and chemistry, (b) his unconventional career, and (c) the 'success' of his program to determine atomic arrangements in crystals and its influence on the work of William Lawrence Bragg.

  4. Terrorism: A Selective Bibliography.

    DTIC Science & Technology

    1984-04-01

    P623 Alexander, Yonah, and Gleason, John M., eds. BEHAVIORAL AND QUANTITATIVE PERSPECTIVES ON TERRORISM. New York, NY: Pergamon Press, 1981. 396 p. HV...CONTROL AND PROSOCIAL ALTERNATIVES. New York, NY: Pergamon Press, 1981. 560 p. RC 569.5 .V55 I5 1981 Gurr, Ted Robert. HANDBOOK OF POLITICAL CONFLICT...Rapoport, David C., and Alexander, Yonah, eds. THE RATIONALIZATION OF TERRORISM. Frederick, MD: Aletheia Books, University Publications of America

  5. Maniac Talk - John Mather

    NASA Image and Video Library

    2014-11-19

    John Mather Maniac Lecture, November 19, 2014 Nobel Laureate John Mather presented a Maniac Talk entitled "Creating the Future: Building JWST, what it may find, and what comes next?" In this lecture, John takes a rear view look at how James Webb Space Telescope was started, what it can see and what it might discover. He describes the hardware, what it was designed to observe, and speculate about the surprises it might uncover. He also outlines a possible future of space observatories: what astronomers want to build, what we need to invent, and what they might find, even the chance of discovering life on planets around other stars.

  6. Growing Community: The Impact of the Stephanie Alexander Kitchen Garden Program on the Social and Learning Environment in Primary Schools

    ERIC Educational Resources Information Center

    Block, Karen; Gibbs, Lisa; Staiger, Petra K.; Gold, Lisa; Johnson, Britt; Macfarlane, Susie; Long, Caroline; Townsend, Mardie

    2012-01-01

    This article presents results from a mixed-method evaluation of a structured cooking and gardening program in Australian primary schools, focusing on program impacts on the social and learning environment of the school. In particular, we address the Stephanie Alexander Kitchen Garden Program objective of providing a pleasurable experience that has…

  7. 77 FR 65623 - Security Zones; USCGC WILLIAM FLORES Commissioning Ceremony, Ybor Channel; Tampa, FL

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-30

    ...-AA87 Security Zones; USCGC WILLIAM FLORES Commissioning Ceremony, Ybor Channel; Tampa, FL AGENCY: Coast... zone on the waters of Ybor Channel in Tampa, Florida around the USCGC WILLIAM FLORES immediately before... FLORES, official parties, dignitaries, the public, and surrounding waterways from terrorist acts...

  8. 77 FR 63308 - J. William Foley Incorporated v. United Illuminating Company; Notice of Complaint

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-16

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EL12-106-000] J. William Foley Incorporated v. United Illuminating Company; Notice of Complaint Take notice that on October 5...) and 825(e), J. William Foley Incorporated (Complainant) filed a formal complaint against United...

  9. Increased overall cortical connectivity with syndrome specific local decreases suggested by atypical sleep-EEG synchronization in Williams syndrome.

    PubMed

    Gombos, Ferenc; Bódizs, Róbert; Kovács, Ilona

    2017-07-21

    Williams syndrome (7q11.23 microdeletion) is characterized by specific alterations in neurocognitive architecture and functioning, as well as disordered sleep. Here we analyze the region, sleep state and frequency-specific EEG synchronization of whole night sleep recordings of 21 Williams syndrome and 21 typically developing age- and gender-matched subjects by calculating weighted phase lag indexes. We found broadband increases in inter- and intrahemispheric neural connectivity for both NREM and REM sleep EEG of Williams syndrome subjects. These effects consisted of increased theta, high sigma, and beta/low gamma synchronization, whereas alpha synchronization was characterized by a peculiar Williams syndrome-specific decrease during NREM states (intra- and interhemispheric centro-temporal) and REM phases of sleep (occipital intra-area synchronization). We also found a decrease in short range, occipital connectivity of NREM sleep EEG theta activity. The striking increased overall synchronization of sleep EEG in Williams syndrome subjects is consistent with the recently reported increase in synaptic and dendritic density in stem-cell based Williams syndrome models, whereas decreased alpha and occipital connectivity might reflect and underpin the altered microarchitecture of primary visual cortex and disordered visuospatial functioning of Williams syndrome subjects.

  10. Dr. Caleb Williams Saleeby: The Complete Eugenicist.

    ERIC Educational Resources Information Center

    Rodwell, Grant

    1997-01-01

    Profiles the work of Dr. Caleb Williams Saleeby, a late 19th-century propagandist for eugenics. Eugenics is a science that deals with the transmission of hereditary racial traits, coupled with a desire to use this for the elimination of social ills. Discusses Saleeby's work with the Eugenics Education Society. (MJP)

  11. Water resources of Prince William Forest Park, Virginia

    USGS Publications Warehouse

    Brown, G. Allan

    1981-01-01

    Prince William Forest Park is in the southern part of Prince William County, Va. Its natural beauty and nearness to Washington, D.C. have made it one of the most popular recreation areas in northern Virginia. To help the National Park Service plan the development of new facilities and effectively manage its total resources, the U.S. Geological Survey made a hydrologic study of the park from October 1972 to November 1975. The overall objective of the Survey 's study was to evalute the quantity and quality of the park 's water resources. Available information was compiled and analyzed, and new data on streamflow, ground-water levels, and the chemical quality of water were collected. Test wells were drilled and aquifer tests made at the sites of wells to evaluate the occurrence and availability of ground water. (USGS)

  12. The Cosmology of William Herschel

    NASA Astrophysics Data System (ADS)

    Hoskin, M.

    2009-08-01

    William Herschel was an amateur astronomer for half his life, until his discovery of Uranus earned him a royal pension. He then set himself to study "the construction of the heavens" with great reflectors, and discovered over 2,500 nebulae and star clusters. Clusters had clearly formed by the action of gravity, and so scattered clusters would in time become ever more compressed: scattered clusters were young, compressed clusters old. This marked the end of the 'clockwork' universe of Newton and Leibniz.

  13. Alexander Hegedus Lightning Talk: Integrating Measurements to Optimize Space Weather Strategies

    NASA Astrophysics Data System (ADS)

    Hegedus, A. M.

    2017-12-01

    Alexander Hegedus is a PhD Candidate at the University of Michigan, and won an Outstanding Student Paper Award at the AGU 2016 Fall Meeting for his poster "Simulating 3D Spacecraft Constellations for Low Frequency Radio Imaging." In this short talk, Alex outlines his current research of analyzing data from both real and simulated instruments to answer Heliophysical questions. He then sketches out future plans to simulate science pipelines in a real-time data assimilation model that uses a Bayesian framework to integrate information from different instruments to determine the efficacy of future Space Weather Alert systems. MHD simulations made with Michigan's own Space Weather Model Framework will provide input to simulated instruments, acting as an Observing System Simulation Experiment to verify that a certain set of measurements can accurately predict different classes of Space Weather events.

  14. 77 FR 58819 - Notice of Submission for OMB Review; Federal Student Aid; William D. Ford Federal Direct Loan...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-24

    ... DEPARTMENT OF EDUCATION Notice of Submission for OMB Review; Federal Student Aid; William D. Ford... William D. Ford Federal Direct Loan Program will use this form to request forbearance on their loans when... of Collection: William D. Ford Federal Direct Loan Program General Forbearance Request. OMB Control...

  15. Williams syndrome predisposes to vascular stiffness modified by antihypertensive use and copy number changes in NCF1.

    PubMed

    Kozel, Beth A; Danback, Joshua R; Waxler, Jessica L; Knutsen, Russell H; de Las Fuentes, Lisa; Reusz, Gyorgy S; Kis, Eva; Bhatt, Ami B; Pober, Barbara R

    2014-01-01

    Williams syndrome is caused by the deletion of 26 to 28 genes, including elastin, on human chromosome 7. Elastin insufficiency leads to the cardiovascular hallmarks of this condition, namely focal stenosis and hypertension. Extrapolation from the Eln(+/-) mouse suggests that affected people may also have stiff vasculature, a risk factor for stroke, myocardial infarction, and cardiac death. NCF1, one of the variably deleted Williams genes, is a component of the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase complex and is involved in the generation of oxidative stress, making it an interesting candidate modifier for vascular stiffness. Using a case-control design, vascular stiffness was evaluated by pulse wave velocity in 77 Williams cases and matched controls. Cases had stiffer conducting vessels than controls (P<0.001), with increased stiffness observed in even the youngest children with Williams syndrome. Pulse wave velocity increased with age at comparable rates in cases and controls, and although the degree of vascular stiffness varied, it was seen in both hypertensive and normotensive Williams participants. Use of antihypertensive medication and extension of the Williams deletion to include NCF1 were associated with protection from vascular stiffness. These findings demonstrate that vascular stiffness is a primary vascular phenotype in Williams syndrome and that treatment with antihypertensives or agents inhibiting oxidative stress may be important in managing patients with this condition, potentially even those who are not overtly hypertensive.

  16. The 2006 Hezbollah-Israeli War: Israel’s Grenada

    DTIC Science & Technology

    2013-05-01

    William M. Arkin, Divining Victory: Airpower in the 2006 Israel-Hezbollah War, (Maxwell Air Force Base, Alabama: Air...Bibliography Arkin, William M. Divining Victory: Airpower in...Operations.” Air and Space Power Journal, (September-October 2012): 118-131. Keegan, John. London Daily Telegraph, 6 June 1999. Kelly , John and David

  17. Clinical utility of an array comparative genomic hybridization analysis for Williams syndrome.

    PubMed

    Yagihashi, Tatsuhiko; Torii, Chiharu; Takahashi, Reiko; Omori, Mikimasa; Kosaki, Rika; Yoshihashi, Hiroshi; Ihara, Masahiro; Minagawa-Kawai, Yasuyo; Yamamoto, Junichi; Takahashi, Takao; Kosaki, Kenjiro

    2014-11-01

    To reveal the relation between intellectual disability and the deleted intervals in Williams syndrome, we performed an array comparative genomic hybridization analysis and standardized developmental testing for 11 patients diagnosed as having Williams syndrome based on fluorescent in situ hybridization testing. One patient had a large 4.2-Mb deletion spanning distally beyond the common 1.5-Mb intervals observed in 10/11 patients. We formulated a linear equation describing the developmental age of the 10 patients with the common deletion; the developmental age of the patient with the 4.2-Mb deletion was significantly below the expectation (developmental age = 0.51 × chronological age). The large deletion may account for the severe intellectual disability; therefore, the use of array comparative genomic hybridization may provide practical information regarding individuals with Williams syndrome. © 2014 Japanese Teratology Society.

  18. 78 FR 77508 - Duke Energy Carolinas, LLC; William States Lee III Nuclear Station, Units 1 and 2; Combined...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-23

    ..., LLC; William States Lee III Nuclear Station, Units 1 and 2; Combined Licenses Application Review... Environmental Impact Statement [EIS] for Combined Licenses (COLs) for William States Lee III Nuclear Station... be accessed online at the NRC's William States Lee III Nuclear Station--specific Web page at: www.nrc...

  19. Williams with TVIS hardware in Zvezda Service module

    NASA Image and Video Library

    2007-02-26

    ISS014-E-15136 (26 Feb. 2007) --- Astronaut Sunita L. Williams, Expedition 14 flight engineer, performs maintenance work on the Treadmill Vibration Isolation System (TVIS) during routine in-flight maintenance (IFM) in the Zvezda Service Module of the International Space Station.

  20. Sir William Jenner (1815-1898) and Queen Victoria.

    PubMed

    Seddon, David; Queen Victoria

    2004-08-01

    This biographical note outlines the work of Sir William Jenner (1815-1898), court physician 1861-93 and President of the Royal College of Physicians 1881-8. He was the first to distinguish between typhoid and typhus both clinically and pathologically.

  1. The contribution of CLIP2 haploinsufficiency to the clinical manifestations of the Williams-Beuren syndrome.

    PubMed

    Vandeweyer, Geert; Van der Aa, Nathalie; Reyniers, Edwin; Kooy, R Frank

    2012-06-08

    Williams-Beuren syndrome is a rare contiguous gene syndrome, characterized by intellectual disability, facial dysmorphisms, connective-tissue abnormalities, cardiac defects, structural brain abnormalities, and transient infantile hypercalcemia. Genes lying telomeric to RFC2, including CLIP2, GTF2I and GTF2IRD1, are currently thought to be the most likely major contributors to the typical Williams syndrome cognitive profile, characterized by a better-than-expected auditory rote-memory ability, a relative sparing of language capabilities, and a severe visual-spatial constructive impairment. Atypical deletions in the region have helped to establish genotype-phenotype correlations. So far, however, hardly any deletions affecting only a single gene in the disease region have been described. We present here two healthy siblings with a pure, hemizygous deletion of CLIP2. A putative role in the cognitive and behavioral abnormalities seen in Williams-Beuren patients has been suggested for this gene on the basis of observations in a knock-out mouse model. The presented siblings did not show any of the clinical features associated with the syndrome. Cognitive testing showed an average IQ for both and no indication of the Williams syndrome cognitive profile. This shows that CLIP2 haploinsufficiency by itself does not lead to the physical or cognitive characteristics of the Williams-Beuren syndrome, nor does it lead to the Williams syndrome cognitive profile. Although contribution of CLIP2 to the phenotype cannot be excluded when it is deleted in combination with other genes, our results support the hypothesis that GTF2IRD1 and GTF2I are the main genes causing the cognitive defects associated with Williams-Beuren syndrome. Copyright © 2012 The American Society of Human Genetics. Published by Elsevier Inc. All rights reserved.

  2. Brief Report: Developing Spatial Frequency Biases for Face Recognition in Autism and Williams Syndrome

    ERIC Educational Resources Information Center

    Leonard, Hayley C.; Annaz, Dagmara; Karmiloff-Smith, Annette; Johnson, Mark H.

    2011-01-01

    The current study investigated whether contrasting face recognition abilities in autism and Williams syndrome could be explained by different spatial frequency biases over developmental time. Typically-developing children and groups with Williams syndrome and autism were asked to recognise faces in which low, middle and high spatial frequency…

  3. Denigrating Carl Rogers: William Coulson's Last Crusade.

    ERIC Educational Resources Information Center

    Kirschenbaum, Howard

    1991-01-01

    Reviews William Coulson's assertions that Carl Rogers, Abraham Maslow, and he initiated the humanistic education field, that Rogers repudiated his philosophy late in life, and that they owe the nation's parents an apology. Argues that these charges are groundless and provides examples and quotations from Rogers' later writings to show how Rogers…

  4. Epistemology in Excess? A Response to Williams

    ERIC Educational Resources Information Center

    Siegei, Harvey

    2017-01-01

    Emma Williams' "In Excess of Epistemology" admirably endeavours to open the way to an account of critical thinking that goes beyond the one I have defended ad nauseum in recent decades by developing, via the work of Charles Taylor and Martin Heidegger, "a radically different conception of thinking and the human being who…

  5. Fears, Hyperacusis and Musicality in Williams Syndrome

    ERIC Educational Resources Information Center

    Blomberg, Stefan; Rosander, Michael; Andersson, Gerhard

    2006-01-01

    The study investigated the prevalence of fear and hyperacusis and the possible connections between fear, hyperacusis and musicality in a Swedish sample of individuals with Williams syndrome (WS). The study included 38 individuals and a cross-sectional design, with no matched control group. Two persons, who knew the participant well, completed a…

  6. Executive Functions in Individuals with Williams Syndrome

    ERIC Educational Resources Information Center

    Menghini, D.; Addona, F.; Costanzo, F.; Vicari, S.

    2010-01-01

    Background: The present study was aimed at investigating working memory (WM) and executive functions capacities in individuals with Williams syndrome (WS) as compared with mental-age matched typically developing (TD) children. Method: In order to serve the study goal, a sizeable battery of tasks tapping WM as well as attention, memory, planning,…

  7. The metallogeny of Late Triassic rifting of the Alexander terrane in southeastern Alaska and northwestern British Columbia

    USGS Publications Warehouse

    Taylor, C.D.; Premo, W.R.; Meier, A.L.; Taggart, J.E.

    2008-01-01

    A belt of unusual volcanogenic massive sulfide (VMS) occurrences is located along the eastern margin of the Alexander terrane throughout southeastern Alaska and northwestern British Columbia and exhibits a range of characteristics consistent with a variety of syngenetic to epigenetic deposit types. Deposits within this belt include Greens Creek and Windy Craggy, the economically most significant VMS deposit in Alaska and the largest in North America, respectively. The occurrences are hosted by a discontinuously exposed, 800-km-long belt of rocks that consist of a 200- to 800-m-thick sequence of conglomerate, limestone, marine elastic sedimentary rocks, and tuff intercalated with and overlain by a distinctive unit of mafic pyroclastic rocks and pillowed flows. Faunal data bracket the age of the host rocks between Anisian (Middle Triassic) and late Norian (late Late Triassic). This metallogenic belt is herein referred to as the Alexander Triassic metallogenic belt. The VMS occurrences show systematic differences in degree of structural control, chemistry, and stratigraphic setting along the Alexander Triassic metallogenic belt that suggest important spatial or temporal changes in the tectonic environment of formation. At the southern end of the belt, felsic volcanic rocks overlain by shallow-water limestones characterize the lower part of the sequence. In the southern and middle portion of the belt, a distinctive pebble conglomerate marks the base of the section and is indicative of high-energy deposition in a near slope or basin margin setting. At the northern end of the belt the conglomerates, limestones, and felsic volcanic rocks are absent and the belt is composed of deep-water sedimentary and mafic volcanic rocks. This northward change in depositional environment and lithofacies is accompanied by a northward transition from epithermal-like structurally controlled, discontinuous, vein- and pod-shaped, Pb-Zn-Ag-Ba-(Cu) occurrences with relatively simple mineralogy

  8. John Dewey, an Appreciation

    ERIC Educational Resources Information Center

    Clopton, Robert W.

    2015-01-01

    The subject of the annual Presidential address of Phi Kappa Phi, presented on May 8, 1962, was John Dewey. Dewey is identified in the public mind chiefly as an educational philosopher. In this address, the author describes the life and work of John Dewey as an indefatigable student of life whose interests ranged, like those of Aristotle, over the…

  9. Williams working in the US Lab during Expedition 15

    NASA Image and Video Library

    2007-06-01

    ISS015-E-10579 (1 June 2007) --- Astronaut Sunita L. Williams, Expedition 15 flight engineer, wears communication headgear while using a computer in the Destiny laboratory of the International Space Station.

  10. Conceptions of Childhood in the Educational Philosophies of John Locke and John Dewey

    ERIC Educational Resources Information Center

    Bynum, Gregory Lewis

    2015-01-01

    This article compares progressive conceptions of childhood in the educational philosophies of John Locke and John Dewey. Although the lives of the two philosophers were separated by an ocean and two centuries of history, they had in common the following things: (1) a relatively high level of experience working with, and observing, children that is…

  11. STS-118 Astronaut Williams and Expedition 15 Engineer Anderson Perform EVA

    NASA Technical Reports Server (NTRS)

    2007-01-01

    As the construction continued on the International Space Station (ISS), STS-118 Astronaut Dave Williams, representing the Canadian Space Agency, participated in the fourth and final session of Extra Vehicular Activity (EVA). During the 5 hour space walk, Williams and Expedition 15 engineer Clay Anderson (out of frame) installed the External Wireless Instrumentation System Antenna, attached a stand for the shuttle robotic arm extension boom, and retrieved the two Materials International Space Station Experiments (MISSE) for return to Earth. MISSE collects information on how different materials weather in the environment of space.

  12. Nature and Nurture: Williams Syndrome across Cultures

    ERIC Educational Resources Information Center

    Zitzer-Comfort, Carol; Doyle, Teresa; Masataka, Nobuo; Korenberg, Julie; Bellugi, Ursula

    2007-01-01

    This study is concerned with ways in which children with Williams syndrome (WS), a rare neurodevelopmental disorder arising from a hemizygous deletion in chromosome band 7q11.23 including the gene for elastin (ELN) and approximately 20 surrounding genes, are affected by social mores of vastly differing cultures: the United States and Japan. WS…

  13. William T. Grant Foundation 2012 Annual Report

    ERIC Educational Resources Information Center

    William T. Grant Foundation, 2013

    2013-01-01

    The William T. Grant Foundation was founded in 1936 to support strong social science research focused on "the enrichment of life, with a primary interest in people and in their adjustment to the world in which they live." Today, its funding priorities reflect this interest in research that affects young people's lives. This Annual Report…

  14. Development of Verbal Passive in Williams Syndrome

    ERIC Educational Resources Information Center

    Perovic, Alexandra; Wexler, Kenneth

    2010-01-01

    Purpose: To experimentally investigate knowledge of passives of actional ("hold") and psychological ("love") verbs in children with Williams syndrome (WS). Passives are usually reported to be in line with mental age in WS. However, studies usually focus on passives of actional verbs only. Method: Twenty-six children with WS, ages 6-16, and 3…

  15. Herbert Hoover and William Shakespeare: Two Writers on Ethics.

    ERIC Educational Resources Information Center

    Somers, Margaret L.

    1979-01-01

    Outlines the ways in which Herbert Hoover and William Shakespeare wrote about professional ethics (for engineers and kings, respectively) using the writing techniques of concreteness, audience awareness, and development by induction. (TJ)

  16. Williams in the U.S. Laboratory during Expedition 13

    NASA Image and Video Library

    2006-08-22

    ISS013-E-70806 (22 Aug. 2006) --- Astronaut Jeffrey N. Williams, Expedition 13 NASA space station science officer and flight engineer, uses a computer in the Destiny laboratory of the International Space Station.

  17. Predictors of specific phobia in children with Williams syndrome.

    PubMed

    Pitts, C H; Klein-Tasman, B P; Osborne, J W; Mervis, C B

    2016-10-01

    Specific phobia (SP) is the most common anxiety disorder among children with Williams syndrome (WS); prevalence rates derived from Diagnostic and Statistical Manual of Mental Disorders-based diagnostic interviews range from 37% to 56%. We evaluated the effects of gender, age, intellectual abilities and/or behaviour regulation difficulties on the likelihood that a child with WS would be diagnosed with SP. A total of 194 6-17 year-olds with WS were evaluated. To best characterise the relations between the predictors and the probability of a SP diagnosis, we explored not only possible linear effects but also curvilinear effects. No gender differences were detected. As age increased, the likelihood of receiving a SP diagnosis decreased. As IQ increased, the probability of receiving a SP diagnosis also decreased. Behaviour regulation difficulties were the strongest predictor of a positive diagnosis. A quadratic relation was detected: The probability of receiving a SP diagnosis gradually rose as behaviour regulation difficulties increased. However, once behaviour regulation difficulties approached the clinical range, the probability of receiving a SP diagnosis asymptoted at a high level. Children with behaviour regulation difficulties in or just below the clinical range were at the greatest risk of developing SP. These findings highlight the value of large samples and the importance of evaluating for nonlinear effects to provide accurate model specification when characterising relations among a dependent variable and possible predictors. © 2016 MENCAP and International Association of the Scientific Study of Intellectual and Developmental Disabilities and John Wiley & Sons Ltd.

  18. Psycholinguistic Abilities of Children with Williams Syndrome

    ERIC Educational Resources Information Center

    Rossi, Natalia F.; Heinze, Elena Garayzabal; Giacheti, Celia M.; Goncalves, Oscar F.; Sampaio, Adriana

    2012-01-01

    The objective of this study was to investigate the psycholinguistic abilities of children with Williams syndrome (WS) and typically developing children using the Illinois Test of Psycholinguistic Abilities (ITPA). Performance on the ITPA was analysed in a group with WS (N=20, mean age=8.5 years, SD=1.62) and two typically developing groups,…

  19. Learning without Awareness Revisited: Extending Williams (2005)

    ERIC Educational Resources Information Center

    Hama, Mika; Leow, Ronald P.

    2010-01-01

    The role of awareness or consciousness in learning has been a relatively contentious issue in non-SLA fields (e.g., cognitive psychology). With the publications of Williams (2004, 2005), a similar debate appears to be brewing in the field of SLA. Contrary to Leow (2000), who reported that unawareness did not appear to play an important role in…

  20. Celebrating John Glenn’s Legacy

    NASA Image and Video Library

    2012-03-02

    Sen. John Glenn, left, shakes hands with former Astronaut Steve Lindsey as NASA Administrator Charles Bolden smiles at an event celebrating John Glenn's legacy and 50 years of americans in orbit held at the Cleveland State University Wolstein Center on Friday, March 3, 2012 in Cleveland, Ohio. In 1998 Lindsey flew onboard the space shuttle Discovery along with then 77 year-old Sen. John Glenn for the STS-95 mission. Glenn became the first American to orbit Earth in 1962. Photo Credit: (NASA/Bill Ingalls)

  1. 78 FR 52169 - Agency Information Collection Activities; Comment Request; William D. Ford Federal Direct Loan...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-22

    ... DEPARTMENT OF EDUCATION [Docket No. ED-2013-ICCD-0109] Agency Information Collection Activities; Comment Request; William D. Ford Federal Direct Loan (Direct Loan) Program Federal Direct PLUS Loan Master... to this notice will be considered public records. Title of Collection: William D. Ford Federal Direct...

  2. Williams syndrome deletions and duplications: Genetic windows to understanding anxiety, sociality, autism, and schizophrenia.

    PubMed

    Crespi, Bernard J; Procyshyn, Tanya L

    2017-08-01

    We describe and evaluate an integrative hypothesis for helping to explain the major neurocognitive features of individuals with Williams syndrome region deletions and duplications. First, we demonstrate how the cognitive differences between Williams syndrome individuals, individuals with duplications of this region, and healthy individuals parallel the differences between individuals subject to effects of increased or decreased oxytocin. Second, we synthesize evidence showing that variation in expression of the gene GTF2I (General Transcription Factor II-I) underlies the primary social phenotypes of Williams syndrome and that common genetic variation in GTF2I mediates oxytocin reactivity, and its correlates, in healthy populations. Third, we describe findings relevant to the hypothesis that the GTF2I gene is subject to parent of origin effects whose behavioral expression fits with predictions from the kinship theory of genomic imprinting. Fourth, we describe how Williams syndrome can be considered, in part, as an autistic syndrome of Lorna Wing's 'active-but-odd' autism subtype, in contrast to associations of duplications with both schizophrenia and autism. Copyright © 2017 Elsevier Ltd. All rights reserved.

  3. Williams syndrome and mature B-Leukemia: A random association?

    PubMed

    Decimi, Valentina; Fazio, Grazia; Dell'Acqua, Fabiola; Maitz, Silvia; Galbiati, Marta; Rizzari, Carmelo; Biondi, Andrea; Cazzaniga, Giovanni; Selicorni, Angelo

    2016-12-01

    Williams syndrome (WBS) is a rare neurodevelopmental disorder with specific phenotypic characteristics and cardiac abnormalities, but is not considered as a cancer predisposing condition. However, in rare cases, malignancies have been described in patients with WBS, with hematologic cancer (mainly Burkitt Lymphoma and Acute Lymphoblastic Leukemia) as the most represented. We report here the case of a boy with WS and B-NHL. This is the unique case within the large cohort of patients (n = 117) followed in our institution for long time (mean clinical follow-up, 13 years). We herewith propose that the BCL7B gene, located in the chromosomal region commonly deleted in Williams syndrome, could potentially have a role in this particular association. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

  4. Noguchi and Williams in hatch area during Expedition 22

    NASA Image and Video Library

    2010-01-03

    ISS022-E-018820 (3 Jan. 2010) --- NASA astronaut Jeffrey Williams (right), Expedition 22 commander; and Japan Aerospace Exploration Agency astronaut Soichi Noguchi, flight engineer, are pictured in a hatch on the International Space Station.

  5. Experiences of Bullying for Individuals with Williams Syndrome

    ERIC Educational Resources Information Center

    Fisher, Marisa H.; Lough, Emma; Griffin, Megan M.; Lane, Laurel A.

    2017-01-01

    Background: Individuals with intellectual disability experience high rates of bullying, but it is not known how people with specific syndromes, such as Williams syndrome (WS), experience and respond to bullying. Given their behavioral profile, including hypersociability and heightened anxiety, and their risk for experiencing other forms of…

  6. Williams with Mission Patches in the A/L

    NASA Image and Video Library

    2016-08-14

    Commander Jeff Williams poses for a photo in the Quest Airlock (A/L) with all of his mission patches. The patches are, from left, STS-101, Soyuz TMA-8, Expedition 13, Soyuz TMA-16, Expedition 21, Expedition 22, Soyuz TMA-20M, Expedition 47, and Expedition 48.

  7. Junior Leader Innovation: William Sims & Continuous Aim Fire

    DTIC Science & Technology

    2012-06-06

    construction ever perpetrated by the white race.” – LT William S. Sims Admiral Sir Percy Scott , Royal Navy...Admiral Mason, Chief, Bureau of Ordnance Ridley McLean “He continued to be a thorn in the fat flesh of the naval hierarchy during his entire

  8. Marginalizing Women: Images of Pregnancy in Williams Obstetrics

    PubMed Central

    Smith, Sheila A.; Condit, Deirdre M.

    2000-01-01

    This research analyzes the historical development of the medical construction of the pregnant body in 17 of 20 editions of Williams Obstetrics, an obstetrical textbook published continually from 1904 to 1997. Examination of the visual imagery of these works produced three key findings. First, depictions of the healthy or “normal” pregnant body are virtually absent throughout the series. Second, visual depictions of women's full bodies adhere to a race-based hierarchy of presentation. Finally, the fundamental discourse about pregnant and female bodies communicated to physicians (primarily) by these images is one of pathology and fragmentation. We conclude that the resulting social and medical construction of the pregnant and female body presented in the Williams series is one of disembodiment, abjection, and ultimately marginality. These findings support recent feminist research that criticizes both the increasing erasure of the person of the women from the medical interpretation of pregnancy and the concomitant decrease in women's perceived sense of empowerment as pregnant beings. PMID:17273202

  9. Commerical Crew Astronaut Suni Williams in SpaceX's Spacesuit

    NASA Image and Video Library

    2018-05-17

    NASA Astronaut Suni Williams, fully suited in SpaceX’s spacesuit, interfaces with the display inside a mock-up of the Crew Dragon spacecraft in Hawthorne, California, during a testing exercise on Tuesday, April 3, 2018.

  10. Conceptualizing neurodevelopmental disorders through a mechanistic understanding of fragile X syndrome and Williams syndrome.

    PubMed

    Fung, Lawrence K; Quintin, Eve-Marie; Haas, Brian W; Reiss, Allan L

    2012-04-01

    The overarching goal of this review is to compare and contrast the cognitive-behavioral features of fragile X syndrome (FraX) and Williams syndrome and to review the putative neural and molecular underpinnings of these features. Information is presented in a framework that provides guiding principles for conceptualizing gene-brain-behavior associations in neurodevelopmental disorders. Abnormalities, in particular cognitive-behavioral domains with similarities in underlying neurodevelopmental correlates, occur in both FraX and Williams syndrome including aberrant frontostriatal pathways leading to executive function deficits, and magnocellular/dorsal visual stream, superior parietal lobe, inferior parietal lobe, and postcentral gyrus abnormalities contributing to deficits in visuospatial function. Compelling cognitive-behavioral and neurodevelopmental contrasts also exist in these two disorders, for example, aberrant amygdala and fusiform cortex structure and function occurring in the context of contrasting social behavioral phenotypes, and temporal cortical and cerebellar abnormalities potentially underlying differences in language function. Abnormal dendritic development is a shared neurodevelopmental morphologic feature between FraX and Williams syndrome. Commonalities in molecular machinery and processes across FraX and Williams syndrome occur as well - microRNAs involved in translational regulation of major synaptic proteins; scaffolding proteins in excitatory synapses; and proteins involved in axonal development. Although the genetic variations leading to FraX and Williams syndrome are different, important similarities and contrasts in the phenotype, neurocircuitry, molecular machinery, and cellular processes in these two disorders allow for a unique approach to conceptualizing gene-brain-behavior links occurring in neurodevelopmental disorders.

  11. 3. Historic American Buildings Survey William C. Everhart, Photographer October ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Historic American Buildings Survey William C. Everhart, Photographer October 1958 FRONT and EAST SIDE ELEVATIONS - Sacred Heart Mission, Interstate 90 & Interchange 39, Cataldo, Shoshone County, ID

  12. 6. Historic American Buildings Survey William C. Everhart, Photographer October ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. Historic American Buildings Survey William C. Everhart, Photographer October 1958 FRONT and WEST SIDE ELEVATIONS - Sacred Heart Mission, Interstate 90 & Interchange 39, Cataldo, Shoshone County, ID

  13. William Herschel and Comets

    NASA Astrophysics Data System (ADS)

    Sullivan, Woodruff

    2018-01-01

    I examine the observational and theoretical researches of William Herschel on 21 comets that he observed over the period 1781 to 1812. Herschel's focus, unlike most contemporaries, was on their physical structure, not their orbits. He forged a strong connection between comets and his nebulae with a scheme of cometary "maturation" (1812) involved a comet traveling from star to star after its central "planetary body'; was born from gravitational collapse of a nebula. During close passages of a star, the comet brightened and lost mass from its atmosphere; at other times, when between stars, it encountered nebulae and was rejuvenated by picking up more mass. Laplace soon adopted these ideas to improve his nebula hypothesis for solar system formation.

  14. Anxiety and Repetitive Behaviours in Autism Spectrum Disorders and Williams Syndrome: A Cross-Syndrome Comparison

    ERIC Educational Resources Information Center

    Rodgers, Jacqui; Riby, Deborah M.; Janes, Emily; Connolly, Brenda; McConachie, Helen

    2012-01-01

    Children with Autism Spectrum Disorder or Williams syndrome are vulnerable to anxiety. The factors that contribute to this risk remain unclear. This study compared anxiety in autism spectrum disorder and Williams Syndrome and examined the relationship between repetitive behaviours and anxiety. Thirty-four children with autism and twenty children…

  15. 34 CFR 662.22 - How does the J. William Fulbright Foreign Scholarship Board select fellows?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 3 2013-07-01 2013-07-01 false How does the J. William Fulbright Foreign Scholarship Board select fellows? 662.22 Section 662.22 Education Regulations of the Offices of the Department of... Foreign Scholarship Board select fellows? (a) The J. William Fulbright Foreign Scholarship Board selects...

  16. 34 CFR 662.22 - How does the J. William Fulbright Foreign Scholarship Board select fellows?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false How does the J. William Fulbright Foreign Scholarship Board select fellows? 662.22 Section 662.22 Education Regulations of the Offices of the Department of... Foreign Scholarship Board select fellows? (a) The J. William Fulbright Foreign Scholarship Board selects...

  17. 34 CFR 662.22 - How does the J. William Fulbright Foreign Scholarship Board select fellows?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 34 Education 3 2014-07-01 2014-07-01 false How does the J. William Fulbright Foreign Scholarship Board select fellows? 662.22 Section 662.22 Education Regulations of the Offices of the Department of... Foreign Scholarship Board select fellows? (a) The J. William Fulbright Foreign Scholarship Board selects...

  18. 34 CFR 662.22 - How does the J. William Fulbright Foreign Scholarship Board select fellows?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 3 2012-07-01 2012-07-01 false How does the J. William Fulbright Foreign Scholarship Board select fellows? 662.22 Section 662.22 Education Regulations of the Offices of the Department of... Foreign Scholarship Board select fellows? (a) The J. William Fulbright Foreign Scholarship Board selects...

  19. 34 CFR 662.22 - How does the J. William Fulbright Foreign Scholarship Board select fellows?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 3 2011-07-01 2011-07-01 false How does the J. William Fulbright Foreign Scholarship Board select fellows? 662.22 Section 662.22 Education Regulations of the Offices of the Department of... Foreign Scholarship Board select fellows? (a) The J. William Fulbright Foreign Scholarship Board selects...

  20. Williams works at the MSG during Expedition 13

    NASA Image and Video Library

    2006-05-04

    ISS013-E-14536 (4 May 2006) --- Astronaut Jeffrey N. Williams, Expedition 13 NASA space station science officer and flight engineer, conducts the first run of the Pore Formation and Mobility Investigation (PFMI) in the Microgravity Science Glovebox (MSG) in the Destiny laboratory of the International Space Station.

  1. Williams works at the MSG during Expedition 13

    NASA Image and Video Library

    2006-05-04

    ISS013-E-14573 (4 May 2006) --- Astronaut Jeffrey N. Williams, Expedition 13 NASA space station science officer and flight engineer, conducts the first run of the Pore Formation and Mobility Investigation (PFMI) in the Microgravity Science Glovebox (MSG) in the Destiny laboratory of the International Space Station.

  2. Williams works at the MSG during Expedition 13

    NASA Image and Video Library

    2006-05-04

    ISS013-E-14524 (4 May 2006) --- Astronaut Jeffrey N. Williams, Expedition 13 NASA space station science officer and flight engineer, conducts the first run of the Pore Formation and Mobility Investigation (PFMI) in the Microgravity Science Glovebox (MSG) in the Destiny laboratory of the International Space Station.

  3. Williams works at the MSG during Expedition 13

    NASA Image and Video Library

    2006-05-04

    ISS013-E-14537 (4 May 2006) --- Astronaut Jeffrey N. Williams, Expedition 13 NASA space station science officer and flight engineer, conducts the first run of the Pore Formation and Mobility Investigation (PFMI) in the Microgravity Science Glovebox (MSG) in the Destiny laboratory of the International Space Station.

  4. Williams works at the MSG during Expedition 13

    NASA Image and Video Library

    2006-05-04

    ISS013-E-14531 (4 May 2006) --- Astronaut Jeffrey N. Williams, Expedition 13 NASA space station science officer and flight engineer, conducts the first run of the Pore Formation and Mobility Investigation (PFMI) in the Microgravity Science Glovebox (MSG) in the Destiny laboratory of the International Space Station.

  5. Electrophysiological Correlates of Semantic Processing in Williams Syndrome

    ERIC Educational Resources Information Center

    Pinheiro, Ana P.; Galdo-Alvarez, Santaigo; Sampaio, Adriana; Niznikiewicz, Margaret; Goncalves, Oscar F.

    2010-01-01

    Williams syndrome (WS), a genetic neurodevelopmental disorder due to microdeletion in chromosome 7, has been described as a syndrome with an intriguing socio-cognitive phenotype. Cognitively, the relative preservation of language and face processing abilities coexists with severe deficits in visual-spatial tasks, as well as in tasks involving…

  6. 7. William E. Barrett, Photographer, August 1975. LOG PONDS LOOKING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. William E. Barrett, Photographer, August 1975. LOG PONDS LOOKING WEST FROM POWERHOUSE ROOF. TRANSFORMER SHED IN FOREGROUND. - Meadow River Lumber Company, Highway 60, Rainelle, Greenbrier County, WV

  7. John Snow, William Farr and the 1849 outbreak of cholera that affected London: a reworking of the data highlights the importance of the water supply.

    PubMed

    Bingham, P; Verlander, N Q; Cheal, M J

    2004-09-01

    This paper examines why Snow's contention that cholera was principally spread by water was not accepted in the 1850s by the medical elite. The consequence of rejection was that hundreds in the UK continued to die. Logistic regression was used to re-analyse data, first published in 1852 by William Farr, consisting of the 1849 mortality rate from cholera and eight potential explanatory variables for the 38 registration districts of London. Logistic regression does not support Farr's original conclusion that a district's elevation above high water was the most important explanatory variable. Elevation above high water, water supply and poor rate each have an independent significant effect on district cholera mortality rate, but in terms of size of effect, it can be argued that water supply most strongly 'invited' further consideration. The science of epidemiology, that Farr helped to found, has continued to advance. Had logistic regression been available to Farr, its application to his 1852 data set would have changed his conclusion.

  8. STS-34 Commander Williams in KSC O and C Bldg prepares for TCDT activities

    NASA Technical Reports Server (NTRS)

    1989-01-01

    STS-34 Commander Donald E. Williams is assisted by technicians with donning his launch and entry suit (LES) in the Kennedy Space Center (KSC) Operations and Checkout (O and C) Building prior to leaving for Launch Complex (LC) Pad 39B during terminal countdown demonstration test (TCDT) activities. Williams also catches a few minutes of relaxation while reclining in his chair.

  9. Long-term outcome of large artificial patch aortic repair for diffuse stenosis in Williams syndrome.

    PubMed

    Sughimoto, Koichi; Takahara, Yoshiharu; Mogi, Kenji; Sakurai, Manabu; Aoki, Chikashi

    2010-10-01

    There have been only a few reports concerning the long-term results of a surgical procedure using a large artificial patch for patients with Williams syndrome. Twelve years have passed since a patient with William's syndrome underwent a surgery with a patch angioplasty for the diffuse supravalvular aortic stenosis and deformities of the neck branch arteries. The patient had a well-balanced aortic growth without stenotic or aneurysmal changes, which was confirmed during the time of the second surgery when replacing the mitral valve. This technique of using a large patch has proven to be safe for Williams syndrome patients with diffuse supravalvular aortic stenosis in the long term.

  10. Speculation on Curriculum from the Perspective of William James.

    ERIC Educational Resources Information Center

    Shubert, William H; Zissis, Georgiana

    1988-01-01

    This article discusses the implications for curriculum theory, research, and practice of William James' thought. Also considered is the question of what curriculum theory and research might be like if James had garnered greater influence than Thorndike. (IAH)

  11. 34 CFR 663.22 - How does the J. William Fulbright Foreign Scholarship Board select fellows?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 3 2013-07-01 2013-07-01 false How does the J. William Fulbright Foreign Scholarship Board select fellows? 663.22 Section 663.22 Education Regulations of the Offices of the Department of... Scholarship Board select fellows? The J. William Fulbright Foreign Scholarship Board selects fellows on the...

  12. 34 CFR 663.22 - How does the J. William Fulbright Foreign Scholarship Board select fellows?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 34 Education 3 2014-07-01 2014-07-01 false How does the J. William Fulbright Foreign Scholarship Board select fellows? 663.22 Section 663.22 Education Regulations of the Offices of the Department of... Scholarship Board select fellows? The J. William Fulbright Foreign Scholarship Board selects fellows on the...

  13. 34 CFR 663.22 - How does the J. William Fulbright Foreign Scholarship Board select fellows?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false How does the J. William Fulbright Foreign Scholarship Board select fellows? 663.22 Section 663.22 Education Regulations of the Offices of the Department of... Scholarship Board select fellows? The J. William Fulbright Foreign Scholarship Board selects fellows on the...

  14. 34 CFR 663.22 - How does the J. William Fulbright Foreign Scholarship Board select fellows?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 3 2011-07-01 2011-07-01 false How does the J. William Fulbright Foreign Scholarship Board select fellows? 663.22 Section 663.22 Education Regulations of the Offices of the Department of... Scholarship Board select fellows? The J. William Fulbright Foreign Scholarship Board selects fellows on the...

  15. 34 CFR 663.22 - How does the J. William Fulbright Foreign Scholarship Board select fellows?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 3 2012-07-01 2012-07-01 false How does the J. William Fulbright Foreign Scholarship Board select fellows? 663.22 Section 663.22 Education Regulations of the Offices of the Department of... Scholarship Board select fellows? The J. William Fulbright Foreign Scholarship Board selects fellows on the...

  16. 22. William E. Barrett, Photographer, August 1975. CHIPPER OR 'HOG' ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    22. William E. Barrett, Photographer, August 1975. CHIPPER OR 'HOG' FOR REDUCING SCRAPS TO WOOD CHIPS. HOUSING PARTIALLY REMOVED. - Meadow River Lumber Company, Highway 60, Rainelle, Greenbrier County, WV

  17. 33 CFR 167.1701 - In Prince William Sound: Precautionary areas.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY OFFSHORE TRAFFIC SEPARATION SCHEMES Description of Traffic Separation Schemes and Precautionary Areas Pacific West Coast § 167.1701 In Prince William Sound...

  18. 76 FR 79228 - Combined Licenses at William States Lee III Nuclear Station Site, Units 1 and 2; Duke Energy...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-21

    ... William States Lee III Nuclear Station Site, Units 1 and 2; Duke Energy Carolinas, LLC AGENCY: Nuclear... Statement for Combined Licenses (COL) for William States Lee III Nuclear Station Units 1 and 2 [Lee Nuclear... draft EIS can be accessed online at the NRC's William States Lee III Nuclear Site Web page at http://www...

  19. Bryan Coast, English Coast, Alexander Island, Fallieres Coast, and Bellingshausen Sea, Antarctica

    NASA Technical Reports Server (NTRS)

    2002-01-01

    This image of Antarctica shows the Bryan Coast (lower left), the English Coast (lower central), Alexander Island (middle right), the Fallieres Coast (top right), and the Bellingshausen Sea. The entire continent has been dedicated to peaceful scientific investigation since 1961, with the signing of the Antarctic Treaty.The waters surrounding Antarctica are intensely cold. Salt water freezes at -2C, allowing sea ice to form. The middle left portion of the image shows quite a lot of sea ice in the Bellingshausen Sea. During the Antarctic winter, when data for this image was acquired, Antarctica doubles in size to about 28.5 million square km (or about 11 million square miles), and temperatures in the -60C range are common.This true-color image was compiled from MODIS data gathered March 29, 2002. Credit: Jacques Descloitres, MODIS Land Rapid Response Team, NASA/GSFC

  20. The chemical work of Alexander and Jane Marcet.

    PubMed

    Rosenfeld, L

    2001-04-01

    Alexander Marcet was an authority on urinary calculi and their analysis when few medical practitioners appreciated the usefulness of chemistry in the explanation and treatment of disease. In An Essay on The Chemical History and Medical Treatment of Calculous Disorders, he described the discovery of an xanthine stone. He drew line illustrations of simple chemical apparatus useful for bedside analysis. His microtechnique used drops of solution and pinhead pieces of calculi; reagents were acids and alkalies and the blowpipe in conjunction with a small alcohol lamp. He reported the earliest description of a disorder later named "alcaptonuria". Marcet's work and that of a few others, on the chemical composition of urine and calculi, laid the foundations of our present knowledge. Between 1807 and 1820, his lectures to the medical students at Guy's Hospital were illustrated by experiments. Jane Haldimand Marcet wrote the very popular CONVERSATIONS: on Chemistry (16 editions in Great Britain). Her book dominated elementary chemical instruction during the first half of the 19th century. She followed Lavoisier's scheme of classification and explained chemical reactions in terms of affinity, aggregation, gravitation, and repulsion. Her advocacy that experimentation accompany lecture was new. The availability of serious scientific education in the new women's academies set the stage for increasing women's involvement in science. She also published a series of CONVERSATIONS: The topics were Political Economy, Natural Philosophy, and Vegetable Physiology.

  1. Adaptive Functioning in Williams Syndrome: A Systematic Review

    ERIC Educational Resources Information Center

    Brawn, Gabrielle; Porter, Melanie

    2018-01-01

    Literature on the level of adaptive functioning and relative strengths and weaknesses in functioning of individuals with Williams syndrome (WS) was reviewed. The electronic databases PsycINFO, PubMed, Expanded Academic, Web of Science, Scopus and ProQuest were searched electronically for relevant articles and dissertations using the search terms…

  2. Ideas of the Founders on Constitutional Government: Resources for Teachers of History and Government.

    ERIC Educational Resources Information Center

    Patrick, John J., Ed.

    The political ideas of John Adams, Alexander Hamilton, John Jay, Thomas Jefferson, James Madison, and other Founders of the United States have been a rich civic legacy for successive generations of citizens. An important means of ensuring that these ideas on constitutional government continue to inspire and guide people in the 21st century lies in…

  3. 77 FR 47374 - Notice of Proposed Information Collection Requests; Federal Student Aid; William D. Ford Federal...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-08

    ... which borrowers in the William D. Ford Federal Direct Loan (Direct Loan) and Federal Family Education... DEPARTMENT OF EDUCATION Notice of Proposed Information Collection Requests; Federal Student Aid; William D. Ford Federal Direct Loan (Direct Loan) Program/ Federal Family Loan (FFEL) Program: Deferment...

  4. 22. Historic American Buildings Survey William F. Winter, Jr., Photographer ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    22. Historic American Buildings Survey William F. Winter, Jr., Photographer 1931 LATHE, THIRD FLOOR, NORTHEAST CORNER - Shaker Church Family Washhouse & Machine Shop, U.S. Route 20, Hancock, Berkshire County, MA

  5. Photographic copy of photograph (original print in possession of William ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of photograph (original print in possession of William Langer Jewel Bearing Plant, Rolla, North Dakota). DRILLING - Turtle Mountain Ordnance Plant, 213 First Street Northwest, Rolla, Rolette County, ND

  6. Photographic copy of photograph (original print in possession of William ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of photograph (original print in possession of William Langer Jewel Bearing Plant, Rolla, North Dakota). OLIVING - Turtle Mountain Ordnance Plant, 213 First Street Northwest, Rolla, Rolette County, ND

  7. 5. William Beardsley standing along canal section. Photographer James Dix ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. William Beardsley standing along canal section. Photographer James Dix Schuyler, 1903. Source: Schuyler report. - Waddell Dam, On Agua Fria River, 35 miles northwest of Phoenix, Phoenix, Maricopa County, AZ

  8. 8. William E. Barrett, Photographer, August 1975. LOG DOCK AND ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. William E. Barrett, Photographer, August 1975. LOG DOCK AND PARTIALLY DEMOLISHED JACKSLIP USED FOR HAULING LOGS UP TO SAWMILL. - Meadow River Lumber Company, Highway 60, Rainelle, Greenbrier County, WV

  9. 6. William E. Barrett, Photographer, 1975. GENERAL VIEW LOOKING EAST. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. William E. Barrett, Photographer, 1975. GENERAL VIEW LOOKING EAST. SAWMILL ON RIGHT. SECONDARY WOODWORKING SHOPS ON LEFT PARTIALLY DEMOLISHED. - Meadow River Lumber Company, Highway 60, Rainelle, Greenbrier County, WV

  10. Impact of the Alexander technique on well-being: a randomised controlled trial involving older adults with visual impairment.

    PubMed

    Gleeson, Michael; Sherrington, Catherine; Lo, Serigne; Auld, Robin; Keay, Lisa

    2017-11-01

    Older adults with visual loss have high rates of depression, restricted participation and reduced quality of life. We sought to measure the impact of lessons in the Alexander technique on vision-related emotional and social well-being, as secondary outcomes to a study on improving physical functioning in this population. This is a single-blind randomised controlled trial. One hundred and twenty community-dwelling adults aged 50 to 90 years with visual impairments were randomised to either 12 Alexander lessons over 12 weeks and usual care or usual care. The Perceived Visual Ability Scale, the Keele Assessment of Participation, the emotional subscale of the Impact of Vision Impairment Profile, the Positive and Negative Affect Scale and the five-item Geriatric Depression Scale were administered at baseline and three and 12 months. Participants were receiving services from Guide Dogs NSW/ACT. None of the validated questionnaires found statistically significant improvements after adjustment for baseline at three or 12 months, although the emotional subscale of the Impact of Vision Impairment approached significance in favour of the intervention group (4.54 points, 95 per cent CI: -0.14 to 9.21, p = 0.06). Depressive symptoms were prevalent and associated with greater impact of visual impairment on emotional well-being (odds ratio: 1.12, 95 per cent CI: 1.07 to 1.17, p < 0.0001). Faster gait, an indicator of general mobility, was associated with less depressive symptoms (odds ratio: 1.27, 95 per cent CI: 1.06 to 1.54, p = 0.01). On average, there was no significant impact of weekly lessons in the Alexander technique on social and emotional well-being, although the emotional impact of visual impairment showed a trend toward less distress in the intervention group. Our data found that emotional distress associated with visual impairment influences depressive symptoms but contrary to expectations, the level of social support received was not significant

  11. Bayesian stock assessment of Pacific herring in Prince William Sound, Alaska.

    PubMed

    Muradian, Melissa L; Branch, Trevor A; Moffitt, Steven D; Hulson, Peter-John F

    2017-01-01

    The Pacific herring (Clupea pallasii) population in Prince William Sound, Alaska crashed in 1993 and has yet to recover, affecting food web dynamics in the Sound and impacting Alaskan communities. To help researchers design and implement the most effective monitoring, management, and recovery programs, a Bayesian assessment of Prince William Sound herring was developed by reformulating the current model used by the Alaska Department of Fish and Game. The Bayesian model estimated pre-fishery spawning biomass of herring age-3 and older in 2013 to be a median of 19,410 mt (95% credibility interval 12,150-31,740 mt), with a 54% probability that biomass in 2013 was below the management limit used to regulate fisheries in Prince William Sound. The main advantages of the Bayesian model are that it can more objectively weight different datasets and provide estimates of uncertainty for model parameters and outputs, unlike the weighted sum-of-squares used in the original model. In addition, the revised model could be used to manage herring stocks with a decision rule that considers both stock status and the uncertainty in stock status.

  12. Bayesian stock assessment of Pacific herring in Prince William Sound, Alaska

    PubMed Central

    Moffitt, Steven D.; Hulson, Peter-John F.

    2017-01-01

    The Pacific herring (Clupea pallasii) population in Prince William Sound, Alaska crashed in 1993 and has yet to recover, affecting food web dynamics in the Sound and impacting Alaskan communities. To help researchers design and implement the most effective monitoring, management, and recovery programs, a Bayesian assessment of Prince William Sound herring was developed by reformulating the current model used by the Alaska Department of Fish and Game. The Bayesian model estimated pre-fishery spawning biomass of herring age-3 and older in 2013 to be a median of 19,410 mt (95% credibility interval 12,150–31,740 mt), with a 54% probability that biomass in 2013 was below the management limit used to regulate fisheries in Prince William Sound. The main advantages of the Bayesian model are that it can more objectively weight different datasets and provide estimates of uncertainty for model parameters and outputs, unlike the weighted sum-of-squares used in the original model. In addition, the revised model could be used to manage herring stocks with a decision rule that considers both stock status and the uncertainty in stock status. PMID:28222151

  13. Edwin James' and John Hinton's revisions of Maclure's geologic map of the United States

    NASA Astrophysics Data System (ADS)

    Aalto, K. R.

    2012-03-01

    William Maclure's pioneering geologic map of the eastern United States, published first in 1809 with Observations on the Geology of the United States, provided a foundation for many later maps - a template from which geologists could extend their mapping westward from the Appalachians. Edwin James, botanist, geologist and surgeon for the 1819/1820 United States Army western exploring expedition under Major Stephen H. Long, published a full account of this expedition with map and geologic sections in 1822-1823. In this he extended Maclure's geology across the Mississippi Valley to the Colorado Rockies. John Howard Hinton (1791-1873) published his widely read text: The History and Topography of the United States in 1832, which included a compilations of Maclure's and James' work in a colored geologic map and vertical sections. All three men were to some degree confounded in their attempts to employ Wernerian rock classification in their mapping and interpretations of geologic history, a common problem in the early 19th Century prior to the demise of Neptunist theory and advent of biostratigraphic techniques of correlation. However, they provided a foundation for the later, more refined mapping and geologic interpretation of the eastern United States.

  14. Reevaluation of Monier-Williams method for determining sulfite in food

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Warner, C.R.; Daniels, D.H.; Joe, F.L. Jr.

    The Monier-Williams distillation procedure has a long history of successful use for determining sulfite in fruit products and wine; however, a systematic evaluation of its accuracy and precision with other food matrices has not been undertaken. The authors found that Monier-Williams distillation yielded >90% recovery of sulfite added to foods such as table grapes, hominy, dried mangoes, and lemon juice. Less than 85% recovery was obtained with broccoli, soda crackers, cheese-peanut butter crackers, mushrooms, and potato chips. These results may, in fact, accurately reflect the residual levels of sulfite if a portion of the sulfite undergoes irreversible reaction with somemore » food components. Analysis of commercial food products gave sulfite levels as 25 ppm in cream sherry.« less

  15. William J. Brennan Jr.: Judicial Architect of Affirmative Action.

    ERIC Educational Resources Information Center

    Eisler, Kim Isaac

    1997-01-01

    More than any other Supreme Court Justice, William Brennan worked to level the playing field for black Americans. As the recognized architect of affirmative action strategies for higher education, he left an indelible imprint on equal education in America. (SLD)

  16. Astronaut William Gregory prepares to exit his sleep quarters

    NASA Technical Reports Server (NTRS)

    1995-01-01

    Astronaut William G. Gregory, STS-67 pilot, ejects a cassette and prepares to bail out of his sleep quarters aboard the Earth orbiting Space Shuttle Endeavour. The astronaut was about to begin a shift of support to the red team.

  17. Conceptualizing neurodevelopmental disorders through a mechanistic understanding of fragile X syndrome and Williams syndrome

    PubMed Central

    Fung, Lawrence K.; Quintin, Eve-Marie; Haas, Brian W.

    2013-01-01

    Purpose of review The overarching goal of this review is to compare and contrast the cognitive-behavioral features of fragile X syndrome (FraX) and Williams syndrome and to review the putative neural and molecular underpinnings of these features. Information is presented in a framework that provides guiding principles for conceptualizing gene-brain-behavior associations in neurodevelopmental disorders. Recent findings Abnormalities, in particular cognitive-behavioral domains with similarities in underlying neurodevelopmental correlates, occur in both FraX and Williams syndrome including aberrant frontostriatal pathways leading to executive function deficits, and magnocellular/dorsal visual stream, superior parietal lobe, inferior parietal lobe, and postcentral gyrus abnormalities contributing to deficits in visuospatial function. Compelling cognitive–behavioral and neurodevelopmental contrasts also exist in these two disorders, for example, aberrant amygdala and fusiform cortex structure and function occurring in the context of contrasting social behavioral phenotypes, and temporal cortical and cerebellar abnormalities potentially underlying differences in language function. Abnormal dendritic development is a shared neurodevelopmental morphologic feature between FraX and Williams syndrome. Commonalities in molecular machinery and processes across FraX and Williams syndrome occur as well – microRNAs involved in translational regulation of major synaptic proteins; scaffolding proteins in excitatory synapses; and proteins involved in axonal development. Summary Although the genetic variations leading to FraX and Williams syndrome are different, important similarities and contrasts in the phenotype, neurocircuitry, molecular machinery, and cellular processes in these two disorders allow for a unique approach to conceptualizing gene–brain–behavior links occurring in neurodevelopmental disorders. PMID:22395002

  18. 8. Historic American Buildings Survey, William Heroy, Photographer November 25, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. Historic American Buildings Survey, William Heroy, Photographer November 25, 1978 FIRST FLOOR, MAIN LOBBY LOOKING TOWARDS THE DRUG STORE. - O. Henry Hotel, North Elm & Bellemeade Streets, Greensboro, Guilford County, NC

  19. Photographic copy of photograph (original print in possession of William ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of photograph (original print in possession of William Langer Jewel Bearing Plant, Rolla, North Dakota). MACHINE SHOP - Turtle Mountain Ordnance Plant, 213 First Street Northwest, Rolla, Rolette County, ND

  20. Photographic copy of photograph (original print in possession of William ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of photograph (original print in possession of William Langer Jewel Bearing Plant, Rolla, North Dakota). FINAL INSPECTION - Turtle Mountain Ordnance Plant, 213 First Street Northwest, Rolla, Rolette County, ND

  1. 2. Historic American Buildings Survey William C. Everhart, Photographer October ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Historic American Buildings Survey William C. Everhart, Photographer October 1958 VIEW FROM THE NORTHEAST (Residence of Caretaker at Left) - Sacred Heart Mission, Interstate 90 & Interchange 39, Cataldo, Shoshone County, ID

  2. 76 FR 13667 - Commercial Furniture Group, Inc., Formerly Known as Falcon Products, Inc., Shelby Williams, Howe...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-14

    ... Furniture Group, Inc., Formerly Known as Falcon Products, Inc., Shelby Williams, Howe and Thonet, Including...., Formerly Known as Falcon Products, Inc., Shelby Williams, Howe and Thonet, Chicago, IL; Amended Certification Regarding Eligibility To Apply for Worker Adjustment Assistance In accordance with Section 223 of...

  3. Inventing Orientation and Mobility Techniques and Teaching Methods: A Conversation with Russell Williams (Part 2)

    ERIC Educational Resources Information Center

    Welsh, Rachard L.

    2005-01-01

    This is the final part of the adaptation from my on-stage conversation with Russell Williams at the 1998 International Mobility conference in Atlanta, GA, which attempted to highlight Williams's contributions to the progression of orientation and mobility from the Army's immediate response to the service men and women who lost their sight during…

  4. A Teacher's Guide for William Shakespeare's "Henry V."

    ERIC Educational Resources Information Center

    WGBH-TV, Boston, MA.

    This teacher's guide for William Shakespeare's play "Henry V" is designed to accompany the Kenneth Branagh Masterpiece Theater film production of the play, and to help teachers use the film in a variety of ways. The guide includes pre-viewing background information, five teaching units, and a pullout poster for classroom display. The…

  5. A salute to William D. Novelli and AARP.

    PubMed

    2006-11-01

    William D. Novelli is the CEO of AARP, the membership organization which represents more than 40 million people over the age of 50. He has made AARP not only the largest, but the most respected association in Washington, D.C. He is known nationwide for his advocacy as well as his philanthropy.

  6. Photographic copy of photograph (original print in possession of William ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of photograph (original print in possession of William Langer Jewel Bearing Plant, Rolla, North Dakota). LARGE HOLE-OPENING - Turtle Mountain Ordnance Plant, 213 First Street Northwest, Rolla, Rolette County, ND

  7. 11. Historic American Buildings Survey William H. Knowles Collection Original: ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. Historic American Buildings Survey William H. Knowles Collection Original: About 1880 Re- photo: January 1940 VIEW FROM SOUTHEAST - Mission San Antonio de Padua, Hunter Liggett Military Reservation, Jolon, Monterey County, CA

  8. John Bahcall and the Solar Neutrino Problem

    NASA Astrophysics Data System (ADS)

    Bahcall, Neta

    2016-03-01

    ``I feel like dancing'', cheered John Bahcall upon hearing the exciting news from the SNO experiment in 2001. The results confirmed, with remarkable accuracy, John's 40-year effort to predict the rate of neutrinos from the Sun based on sophisticated Solar models. What began in 1962 by John Bahcall and Ray Davis as a pioneering project to test and confirm how the Sun shines, quickly turned into a four-decade-long mystery of the `Solar Neutrino Problem': John's models predicted a higher rate of neutrinos than detected by Davis and follow-up experiments. Was the theory of the Sun wrong? Were John's calculations in error? Were the neutrino experiments wrong? John worked tirelessly to understand the physics behind the Solar Neutrino Problem; he led the efforts to greatly increase the accurately of the solar model, to understand its seismology and neutrino fluxes, to use the neutrino fluxes as a test for new physics, and to advocate for important new experiments. It slowly became clear that none of the then discussed possibilities --- error in the Solar model or neutrino experiments --- was the culprit. The SNO results revealed that John's calculations, and hence the theory of the Solar model, have been correct all along. Comparison of the data with John's theory demanded new physics --- neutrino oscillations. The Solar Neutrino saga is one of the most amazing scientific stories of the century: exploring a simple question of `How the Sun Shines?' led to the discovery of new physics. John's theoretical calculations are an integral part of this journey; they provide the foundation for the Solar Neutrino Problem, for confirming how the Sun shines, and for the need of neutrino oscillations. His tenacious persistence, dedication, enthusiasm and love for the project, and his leadership and advocacy of neutrino physics over many decades are a remarkable story of scientific triumph. I know John is smiling today.

  9. WE-G-213-02: The AAPM Award Eponyms: William D. Coolidge, Edith H. Quimby, and Marvin M.D. Williams - Who Were They and What Did They Do?

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rothenberg, L.

    Roentgen and the Birth of Modern Medical Physics – Perry Sprawls Wilhelm Roentgen is well known for his discovery of x-radiation. What is less known and appreciated is his intensive research following the discovery to determine the characteristics of the “new kind of radiation” and demonstrate its great value for medical purposes. In this presentation we will imagine ourselves in Roentgen’s mind and follow his thinking, including questions and doubts, as he designs and conducts a series of innovative experiments that provided the foundation for the rapid growth of medical physics. Learning Objectives: Become familiar with the personal characteristics andmore » work of Prof. Roentgen that establishes him as an inspiring model for the medical physics profession. Observe the thought process and experiments that determined and demonstrated the comprehensive characteristics of x-radiation. The AAPM Award Eponyms: William D. Coolidge, Edith H. Quimby, and Marvin M.D. Williams - Who were they and what did they do? – Lawrence N. Rothenberg William David Coolidge (1873–1975) William Coolidge was born in Hudson, NY in 1873. He obtained his BS at the Massacusetts Institute of Technology in 1896. Coolidge then went to the University of Leipzig, Germany for graduate study with physicists Paul Drude and Gustave Wiedemann and received a Ph.D. in 1899. While in Germany he met Wilhelm Roentgen. Coolidge returned to the US to teach at MIT where he was associated with Arthur A. Noyes of the Chemistry Department, working on the electrical conductivity of aqueous solutions. Willis R. Whitney, under whom Coolidge had worked before going to Germany, became head of the newly formed General Electric Research Laboratory and he invited Coolidge to work with him. In 1905, Coolidge joined the staff of the GE laboratory and was associated with it for the remainder of his life. He developed ductile tungsten filaments to replace fragile carbon filaments as the material for electric

  10. Improving Learning Outcomes, Persistence, and Graduation Rates of Academically Underprepared Students: a Case Study of Alexander Community College and Its Developmental Education Effort

    ERIC Educational Resources Information Center

    Marchione, Susan M.

    2012-01-01

    This case study describes how Alexander Community College (ACC), a two-year State University of New York (SUNY) institution is addressing challenges associated with its developmental education effort--primarily high costs for repeated developmental (assumed by the institution and students) and low persistence and graduation rates for developmental…

  11. 32. William E. Barrett, Photographer, 1973. DEADEND WELL WITH WOODEN ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    32. William E. Barrett, Photographer, 1973. DEAD-END WELL WITH WOODEN OIL TANK, PIPE ROCKER ARM. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  12. 24. INTERIOR VIEW, WILLIAM GRAY AT SIZING GUAGE ADJACENT TO ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    24. INTERIOR VIEW, WILLIAM GRAY AT SIZING GUAGE ADJACENT TO BRADLEY HAMMER; NOTE THIS IS THE SAME TOOL AS BEING FORGED ABOVE - Warwood Tool Company, Foot of Nineteenth Street, Wheeling, Ohio County, WV

  13. Orientation Perception in Williams Syndrome: Discrimination and Integration

    ERIC Educational Resources Information Center

    Palomares, Melanie; Landau, Barbara; Egeth, Howard

    2009-01-01

    Williams Syndrome (WS) is a rare neurodevelopmental disorder, which stems from a genetic deletion on chromosome 7 and causes a profound weakness in visuospatial cognition. Our current study explores how orientation perception may contribute to the visuospatial deficits in WS. In Experiment 1, we found that WS individuals and normal 3-4 year olds…

  14. Williams with TVIS hardware in Zvezda Service module

    NASA Image and Video Library

    2007-02-27

    ISS014-E-15349 (27 Feb. 2007) --- Assisted by the weightlessness of space, astronaut Sunita L. Williams, Expedition 14 flight engineer, hoists the Treadmill Vibration Isolation System (TVIS). She took a moment to pose for a photo during routine in-flight maintenance (IFM) on TVIS in the Zvezda Service Module of the International Space Station.

  15. Astronaut Sunita L. Williams Submerges Into Waters of the Neutral Buoyancy Laboratory (NBL)

    NASA Technical Reports Server (NTRS)

    2006-01-01

    Astronauts Sunita L. Williams, Expedition 14 flight engineer, and Robert L. Curbeam (partially obscured), STS-116 mission specialist, are about to be submerged in the waters of the Neutral Buoyancy Laboratory (NBL) near Johnson Space Center. Williams and Curbeam are attired in training versions of the Extravehicular Mobility Unit (EMU) space suit. SCUBA-equipped divers are in the water to assist the crew members in their rehearsal intended to help prepare them for work on the exterior of the International Space Station (ISS).

  16. Horatio Nelson and the 1798 Mediterranean Campaign

    DTIC Science & Technology

    2006-01-01

    status as Duke of Bronte. Dates preceded by names Theseus , Captain, Vanguard or Victory are referring to Nelson’s flagships, from whence he wrote many...Guns 590 Men 2. Theseus R.W. Miller, Captain 74 Guns 590 Men 3. Alexander Alex. John Ball, Captain 74 Guns 590 Men 4. Vanguard Rear-Admiral...1798, OFF THE MOUTH OF THE NILE. Theseus .—5 Seamen killed; 1 Officer, 24 Seamen, 5 Marines wounded. —Total 35. Alexander.—1 Officer, 13 Seamen

  17. Hydrologic conditions in the Bill Williams River National Wildlife Refuge and Planet Valley, Arizona, 2000

    USGS Publications Warehouse

    Wilson, Richard P.; Owen-Joyce, Sandra J.

    2002-01-01

    During a period of sustained base-flow conditions in the Bill Williams River below Alamo Dam in west central Arizona from March to July 2000, the channel of the river through Planet Valley was dry, and the water table sloped almost due west parallel to the main slope of the flood plain. Water from the river infiltrated into the channel bottom at the head of Planet Valley, moved downgradient in the subsurface, and reappeared in the channel about 0.3 mile downstream from the east boundary of the Bill Williams River National Wildlife Refuge. A river aquifer in hydraulic connection with the Bill Williams River was mapped from a point 6.3 miles upstream from Highway 95 to the upstream end of Planet Valley. Formations that make up the river aquifer in Planet Valley are younger alluvium, older alluviums, and fanglomerate. Total thickness of the river aquifer probably is less than 200 feet in the bedrock canyons to as much as 1,035 feet in Planet Valley. The purpose of this study was to investigate the current hydrologic conditions along the Bill Williams River, which included an inventory of wells within the river aquifer of the Colorado River and in Planet Valley, and to determine the configuration of the water table. A map shows the elevation and configuration of the water table from the east end of Planet Valley to the confluence of the Bill Williams River with Lake Havasu.

  18. William James, Nitrous Oxide, and the Anaesthetic Revelation.

    PubMed

    Moon, Jane S; Kuza, Catherine M; Desai, Manisha S

    2018-01-01

    William James greatly influenced the fields of psychology, philosophy, and religion during the late 19 th and early 20 th centuries. This was the era of Modernism, a time when many writers rejected the certainty of Enlightenment ideals. Positivism, which rose to prominence in the early 19th century, had emphasized physical phenomena, empirical evidence, and the scientific method. Darwin's On the Origin of Species (1859), with its theory of natural selection, provided an explanation for the evolution of species apart from a divine Creator. Within this context, William James served as a "mediator between scientific agnosticism and the religious view of the world." James' own experience inhaling nitrous oxide played an important role in shaping his views. For James, the use of nitrous oxide served a key role in elucidating some of his most central ideas: 1) the value of religion, and the emphasis on mysticism and revelation (as opposed to theology and doctrine) as religion's foundation; 2) the universe as pluralistic (as opposed to absolutist, constant, eternal), driven by chance, experience, and change. Copyright © 2017 Elsevier Inc. All rights reserved.

  19. Obituary: John Louis Perdrix, 1926-2005

    NASA Astrophysics Data System (ADS)

    Orchiston, D. Wayne

    2006-12-01

    John Perdrix, astronomical historian and co-founder of the Journal of Astronomical History and Heritage, died on 27 June 2005. John Louis Perdrix was born in Adelaide, Australia, on 30 June 1926. After studying chemistry at Melbourne Technical College and working in industry, he joined the Commonwealth Scientific and Industrial Research Organisation's Division of Minerals and Geochemistry. In 1974 the Division relocated to the Western Australian capital, Perth, and John spent the rest of his working life there involved in geochemical research. From his teenage years John had a passion for astronomy, which he fine-tuned through the Astronomical Society of Victoria and the Victorian Branch of the British Astronomical Association. He was very active in both groups, serving as President of the former and Secretary/Treasurer of the latter. He was also an FRAS, and a member of the AAS, the BAA parent body, and the IAU (Commission 41)?no mean feat for an Australian amateur astronomer. Throughout his life, he was a strong advocate of close amateur-professional relations. John's main research interest was history of astronomy, and over the years he wrote a succession of research papers, mainly about aspects of Australian astronomy. His well-researched and neatly-illustrated papers on the Melbourne Observatory and the Great Melbourne Telescope are classics, and when the Observatory's future was in the balance they played a key role in the State Government's decision to convert this unique facility into a museum precinct. To support his research activities, John built up an amazing library that developed its own distinctive personality and quickly took over his house and garage before invading commercial storage facilities! Apart from writing papers, John had an even greater passion for editing and publishing. From 1985 to 1997 he produced the Australian Journal of Astronomy, and in 1998 this was replaced by the Journal of Astronomical History and Heritage (JAH2). Both

  20. Health and Social Outcomes in Adults with Williams Syndrome: Findings from Cross-Sectional and Longitudinal Cohorts

    ERIC Educational Resources Information Center

    Elison, Sarah; Stinton, Chris; Howlin, Patricia

    2010-01-01

    Previous studies have investigated trajectories of cognitive, language and adaptive functioning in Williams syndrome (WS) but little is known about how other aspects of the Williams syndrome behavioural phenotype change across the life-span. Therefore, the present study examined age associated changes in a number of different domains of…

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