Sample records for joint research efforts

  1. 76 FR 8788 - National Nanotechnology Coordination Office; Bridging NanoEHS Research Efforts: A Joint US-EU...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-15

    ... OFFICE OF SCIENCE AND TECHNOLOGY POLICY National Nanotechnology Coordination Office; Bridging NanoEHS Research Efforts: A Joint US-EU Workshop: Public Meeting AGENCY: National Nanotechnology Coordination Office, STPO. ACTION: Notice of public meeting. SUMMARY: The National Nanotechnology Coordination...

  2. Assessing country-level efforts to link research to action.

    PubMed Central

    Lavis, John N.; Lomas, Jonathan; Hamid, Maimunah; Sewankambo, Nelson K.

    2006-01-01

    We developed a framework for assessing country-level efforts to link research to action. The framework has four elements. The first element assesses the general climate (how those who fund research, universities, researchers and users of research support or place value on efforts to link research to action). The second element addresses the production of research (how priority setting ensures that users' needs are identified and how scoping reviews, systematic reviews and single studies are undertaken to address these needs). The third element addresses the mix of four clusters of activities used to link research to action. These include push efforts (how strategies are used to support action based on the messages arising from research), efforts to facilitate "user pull" (how "one-stop shopping" is provided for optimally packaged high-quality reviews either alone or as part of a national electronic library for health, how these reviews are profiled during "teachable moments" such as intense media coverage, and how rapid-response units meet users' needs for the best research), "user pull" efforts undertaken by those who use research (how users assess their capacity to use research and how structures and processes are changed to support the use of research) and exchange efforts (how meaningful partnerships between researchers and users help them to jointly ask and answer relevant questions). The fourth element addresses approaches to evaluation (how support is provided for rigorous evaluations of efforts to link research to action). PMID:16917649

  3. Strategy of arm movement control is determined by minimization of neural effort for joint coordination.

    PubMed

    Dounskaia, Natalia; Shimansky, Yury

    2016-06-01

    Optimality criteria underlying organization of arm movements are often validated by testing their ability to adequately predict hand trajectories. However, kinematic redundancy of the arm allows production of the same hand trajectory through different joint coordination patterns. We therefore consider movement optimality at the level of joint coordination patterns. A review of studies of multi-joint movement control suggests that a 'trailing' pattern of joint control is consistently observed during which a single ('leading') joint is rotated actively and interaction torque produced by this joint is the primary contributor to the motion of the other ('trailing') joints. A tendency to use the trailing pattern whenever the kinematic redundancy is sufficient and increased utilization of this pattern during skillful movements suggests optimality of the trailing pattern. The goal of this study is to determine the cost function minimization of which predicts the trailing pattern. We show that extensive experimental testing of many known cost functions cannot successfully explain optimality of the trailing pattern. We therefore propose a novel cost function that represents neural effort for joint coordination. That effort is quantified as the cost of neural information processing required for joint coordination. We show that a tendency to reduce this 'neurocomputational' cost predicts the trailing pattern and that the theoretically developed predictions fully agree with the experimental findings on control of multi-joint movements. Implications for future research of the suggested interpretation of the trailing joint control pattern and the theory of joint coordination underlying it are discussed.

  4. Joint research effort on vibrations of twisted plates, phase 1: Final results

    NASA Technical Reports Server (NTRS)

    Kielb, R. E.; Leissa, A. W.; Macbain, J. C.; Carney, K. S.

    1985-01-01

    The complete theoretical and experimental results of the first phase of a joint government/industry/university research study on the vibration characteristics of twisted cantilever plates are given. The study is conducted to generate an experimental data base and to compare many different theoretical methods with each other and with the experimental results. Plates with aspect ratios, thickness ratios, and twist angles representative of current gas turbine engine blading are investigated. The theoretical results are generated by numerous finite element, shell, and beam analysis methods. The experimental results are obtained by precision matching a set of twisted plates and testing them at two laboratories. The second and final phase of the study will concern the effects of rotation.

  5. Joint Contributions of Negative Emotionality, Positive Emotionality, and Effortful Control on Depressive Symptoms in Youth.

    PubMed

    Van Beveren, Marie-Lotte; Mezulis, Amy; Wante, Laura; Braet, Caroline

    2016-11-02

    From a clinical developmental perspective, temperament has been shown to confer vulnerability to depression among youth. High negative emotionality (NE), low positive emotionality (PE), and low effortful control (EC) have repeatedly been independently associated with youth depressive symptoms. However, far less research has examined the joint contributions of NE, PE, and EC on such symptoms. The present study builds upon previous research by examining how NE, PE, and EC jointly predict change in depressive symptoms over time among 211 youngsters (7-14 years, M = 10.7, SD = 1.81) who participated in an 8-month prospective study. Self-reported temperament and symptoms were assessed at baseline; self-reported symptoms were measured again at follow-up. Results suggest that all 3 temperamental traits need to be considered jointly in predicting change in depressive symptoms. Furthermore, results provide further support for the "best two out of three" principle. Surprisingly, results reveal that high EC might be maladaptive in the context of high emotional reactivity. Last, results show that the combination of high NE and low EC could be a possible pathway to the development of symptoms. The current study clarified how NE, PE, and EC may jointly confer risk-or protection for developing depressive symptoms during adolescence. The results highlight the need of taking into account all three temperamental traits in order to provide a more nuanced understanding of the risk for developing depressive symptoms at an early stage, as well as to provide customized care targeting temperamental vulnerability in depressed youth.

  6. Neural control of arm movements reveals a tendency to use gravity to simplify joint coordination rather than to decrease muscle effort.

    PubMed

    Wang, Wanyue; Dounskaia, Natalia

    2016-12-17

    How gravity influences neural control of arm movements remains under debate. We tested three alternative interpretations suggested by previous research: (1) that muscular control includes two components, tonic which compensates for gravity and phasic which produces the movement; (2) that there is a tendency to exploit gravity to reduce muscle effort; and (3) that there is a tendency to use a trailing pattern of joint control during which either the shoulder or elbow is rotated actively and the other joint rotates predominantly passively, and to exploit gravity for control of the passively rotated joint. A free-stroke drawing task was performed that required production of center-out strokes within a circle while selecting stroke directions randomly. The circle was positioned in the horizontal, sagittal, and frontal plane. The arm joints freely rotated in space. In each plane, the distribution of the strokes across directions was non-uniform. Directional histograms were built and their peaks were used to identify preferred movement directions. The directional preferences were especially pronounced in the two vertical planes. The upward directions were most preferred. To test the three interpretations, we used a kinetic analysis that determined the role of gravitational torque in the production of movement in the preferred directions. The results supported the third interpretation and provided evidence against the first and second interpretation. The trailing pattern has been associated with reduced neural effort for joint coordination, and therefore, we conclude that the major tendency with respect to gravity is to exploit it for simplification of joint coordination. Copyright © 2016 IBRO. Published by Elsevier Ltd. All rights reserved.

  7. Joint Advertising Market Research & Studies (JAMRS)

    Science.gov Websites

    Market Research & Studies Marketing Communications Recruiting Database Affiliations WELCOME TO JOINT joint marketing communications and market research and studies. One of JAMRS' objectives is to explore reported to Congress. Our marketing communications programs help increase awareness and broaden people's

  8. Joint Online Thesis and Research System (JOTARS)

    DTIC Science & Technology

    2006-09-01

    NAVAL POSTGRADUATE SCHOOL MONTEREY, CALIFORNIA THESIS Approved for public release; distribution is unlimited JOINT ONLINE ...September 2006 3. REPORT TYPE AND DATES COVERED Master’s Thesis 4. TITLE AND SUBTITLE: Joint Online Thesis and Research System (JOTARS) 6. AUTHOR...prototype website is the Joint Online Thesis and Research System (JOTARS). The specific functional objectives of JOTARS are to establish standard

  9. Estimations of relative effort during sit-to-stand increase when accounting for variations in maximum voluntary torque with joint angle and angular velocity.

    PubMed

    Bieryla, Kathleen A; Anderson, Dennis E; Madigan, Michael L

    2009-02-01

    The main purpose of this study was to compare three methods of determining relative effort during sit-to-stand (STS). Fourteen young (mean 19.6+/-SD 1.2 years old) and 17 older (61.7+/-5.5 years old) adults completed six STS trials at three speeds: slow, normal, and fast. Sagittal plane joint torques at the hip, knee, and ankle were calculated through inverse dynamics. Isometric and isokinetic maximum voluntary contractions (MVC) for the hip, knee, and ankle were collected and used for model parameters to predict the participant-specific maximum voluntary joint torque. Three different measures of relative effort were determined by normalizing STS joint torques to three different estimates of maximum voluntary torque. Relative effort at the hip, knee, and ankle were higher when accounting for variations in maximum voluntary torque with joint angle and angular velocity (hip=26.3+/-13.5%, knee=78.4+/-32.2%, ankle=27.9+/-14.1%) compared to methods which do not account for these variations (hip=23.5+/-11.7%, knee=51.7+/-15.0%, ankle=20.7+/-10.4%). At higher velocities, the difference in calculating relative effort with respect to isometric MVC or incorporating joint angle and angular velocity became more evident. Estimates of relative effort that account for the variations in maximum voluntary torque with joint angle and angular velocity may provide higher levels of accuracy compared to methods based on measurements of maximal isometric torques.

  10. Green Roof Research through EPA's Regional Applied Research Effort

    EPA Science Inventory

    ABSTRACT The U.S. Environmental Protection Agency’s (EPA) Regional Applied Research Effort (RARE) allows the Regions of the EPA to choose research projects to be performed in partnership with EPA’s Office of Research and Development (ORD). Over the last decade, several green roo...

  11. New generation of space capabilities resulting from US/RF cooperative efforts

    NASA Astrophysics Data System (ADS)

    Humpherys, Thomas; Misnik, Victor; Sinelshchikov, Valery; Stair, A. T., Jr.; Khatulev, Valery; Carpenter, Jack; Watson, John; Chvanov, Dmitry; Privalsky, Victor

    2006-09-01

    Previous successful international cooperative efforts offer a wealth of experience in dealing with highly sensitive issues, but cooperative remote sensing for monitoring and understanding the global environmental is in the national interest of all countries. Cooperation between international partners is paramount, particularly with the Russian Federation, due to its technological maturity and strategic political and geographical position in the world. Based on experience gained over a decade of collaborative space research efforts, continued cooperation provides an achievable goal as well as understanding the fabric of our coexistence. Past cooperative space research efforts demonstrate the ability of the US and Russian Federation to develop a framework for cooperation, working together on a complex, state-of-the-art joint satellite program. These efforts consisted of teams of scientists and engineers who overcame numerous cultural, linguistic, engineering approaches and different political environments. Among these major achievements are: (1) field measurement activities with US satellites MSTI and MSX and the Russian RESURS-1 satellite, as well as the joint experimental use of the US FISTA aircraft; (2) successful joint Science, Conceptual and Preliminary Design Reviews; (3) joint publications of scientific research technical papers, (4) Russian investment in development, demonstration and operation of the Monitor-E spacecraft (Yacht satellite bus), (5) successful demonstration of the conversion of the SS-19 into a satellite launch system, and (6) negotiation of contractual and technical assistant agreements. This paper discusses a new generation of science and space capabilities available to the Remote Sensing community. Specific topics include: joint requirements definition process and work allocation for hardware and responsibility for software development; the function, description and status of Russian contributions in providing space component prototypes

  12. Identifying research priorities for health care priority setting: a collaborative effort between managers and researchers

    PubMed Central

    Smith, Neale; Mitton, Craig; Peacock, Stuart; Cornelissen, Evelyn; MacLeod, Stuart

    2009-01-01

    Background To date there has been relatively little published about how research priorities are set, and even less about methods by which decision-makers can be engaged in defining a relevant and appropriate research agenda. We report on a recent effort in British Columbia to have researchers and decision-makers jointly establish an agenda for future research into questions of resource allocation. Methods The researchers enlisted decision-maker partners from each of British Columbia's six health authorities. Three forums were held, at which researchers and decision-makers from various levels in the health authorities considered possible research areas related to three key focus areas: (1) generation and use of decision criteria and measurement of 'benefit' against such criteria; (2) identification of so-called 'disinvestment' opportunities; and (3) evaluation of the effectiveness of priority setting procedures. Detailed notes were taken from each forum and synthesized into a set of qualitative themes. Results Forum participants suggested that future research into healthcare priority setting would benefit from studies that were longitudinal, comparative, and/or interdisciplinary. As well, participants identified two broad theme areas in which specific research projects were deemed desirable. First, future research might usefully consider how formal priority setting and resource allocation projects are situated within a larger organizational and political context. Second, additional research efforts should be devoted to better understanding and improving the actual implementation of priority setting frameworks, particularly with respect to issues of change management and the resolution of impediments to action on recommendations for resource allocation. Conclusion We were able to validate the importance of initial areas posed to the group and observed emergence of additional concerns and directions of critical importance to these decision-makers at this time. It is

  13. Green Roof Research through EPA's Regional Applied Research Effort - slides

    EPA Science Inventory

    The U.S. Environmental Protection Agency’s (EPA) Regional Applied Research Effort (RARE) allows the Regions of the EPA to choose research projects to be performed in partnership with EPA’s Office of Research and Development (ORD). Over the last decade, several green roof projects...

  14. Joint University Program for Air Transportation Research, 1984

    NASA Technical Reports Server (NTRS)

    Morrell, Frederick R. (Compiler)

    1987-01-01

    The research conducted during 1984 under the NASA/FAA sponsored Joint University Program for Air Transportation Research is summarized. The Joint University Program is a coordinated set of three grants sponsored by NASA Langley Research Center and the Federal Aviation Administration, one each with the Massachusetts Institute of Technology, Ohio University, and Princeton University. Completed works, status reports, and bibliographies are presented for research topics, which include navigation, guidance, control and display concepts. An overview of the year's activities for each of the schools is also presented.

  15. A Mentoring Opportunity: A Joint Effort in Writing Letters of Recommendation.

    PubMed

    Master, Zubin

    2017-01-01

    Integrity in writing letters of recommendation is important to academic research because it is an influential criterion used pervasively in peer review. While research in the integrity of recommendation letters has concentrated on contents of the letter, bias, and reliability, few have questioned the process of letter writing. Here, I argue that letter writing should be a joint opportunity between mentor/supervisor/advisor and trainee. It results in more compelling letters, may prevent errors and the use of biased language, and serves as an excellent mentoring opportunity promoting self-reflection.

  16. Overview of NASA Magnet and Linear Alternator Research Efforts

    NASA Astrophysics Data System (ADS)

    Geng, Steven M.; Niedra, Janis M.; Schwarze, Gene E.

    2005-02-01

    The Department of Energy, Lockheed Martin, Stirling Technology Company, and NASA Glenn Research Center are developing a high-efficiency, 110 watt Stirling Radioisotope Generator (SRG110) for NASA Space Science missions. NASA Glenn is conducting in-house research on rare earth permanent magnets and on linear alternators to assist in developing a free-piston Stirling convertor for the SRG110 and for developing advanced technology. The permanent magnet research efforts include magnet characterization, short-term magnet aging tests, and long-term magnet aging tests. Linear alternator research efforts have begun just recently at GRC with the characterization of a moving iron type linear alternator using GRC's alternator test rig. This paper reports on the progress and future plans of GRC's magnet and linear alternator research efforts.

  17. Overview of NASA Magnet and Linear Alternator Research Efforts

    NASA Technical Reports Server (NTRS)

    Geng, Steven M.; Schwarze, Gene E.; Nieda, Janis M.

    2005-01-01

    The Department of Energy, Lockheed Martin, Stirling Technology Company, and NASA Glenn Research Center are developing a high-efficiency, 110 watt Stirling Radioisotope Generator (SRG110) for NASA Space Science missions. NASA Glenn is conducting in-house research on rare earth permanent magnets and on linear alternators to assist in developing a free-piston Stirling convertor for the SRG110 and for developing advanced technology. The permanent magnet research efforts include magnet characterization, short-term magnet aging tests, and long-term magnet aging tests. Linear alternator research efforts have begun just recently at GRC with the characterization of a moving iron type linear alternator using GRC's alternator test rig. This paper reports on the progress and future plans of GRC's magnet and linear alternator research efforts.

  18. Joint University Program for Air Transportation Research, 1986

    NASA Technical Reports Server (NTRS)

    Morrell, Frederick R. (Compiler)

    1988-01-01

    The research conducted under the NASA/FAA sponsored Joint University Program for Air Transportation Research is summarized. The Joint University Program is a coordinated set of three grants sponsored by NASA and the FAA, one each with the Mass. Inst. of Tech., Ohio Univ., and Princeton Univ. Completed works, status reports, and bibliographies are presented for research topics, which include computer science, guidance and control theory and practice, aircraft performance, flight dynamics, and applied experimental psychology. An overview of activities is presented.

  19. Joint University Program for Air Transportation Research, 1987

    NASA Technical Reports Server (NTRS)

    Morrell, Frederick R. (Compiler)

    1989-01-01

    The research conducted during 1987 under the NASA/FAA sponsored Joint University Program for Air Transportation Research is summarized. The Joint University Program is a coordinated set of 3 grants sponsored by NASA-Langley and the FAA, one each with the MIT, Ohio Univ., and Princeton Univ. Completed works, status reports, and annotated bibliographies are presented for research topics, which include computer science, guidance and control theory and practice, aircraft performance, flight dynamics, and applied experimental psychology. An overview of the year's activities for each university is also presented.

  20. Senior Student Affairs Officers' Reports of Joint Intra-Institutional Efforts to Support College Students with Mental Illness

    ERIC Educational Resources Information Center

    Scheidel, Sarah

    2016-01-01

    The purpose of this sequential mixed-methods study was to explore senior student affairs officers' reports of joint intra-institutional efforts within the past three years to achieve the common goal of supporting the academic and personal success of college students with mental illness. The 20 factors identified by Mattessich, Murray-Close, and…

  1. Design considerations for bridge deck joint-sealing systems : summary report.

    DOT National Transportation Integrated Search

    1992-07-01

    This is a report summary which summarizes a three year research effort related to the study of bridge deck expansion joint movements. Bridge deck expansion joint systems often develop serious problems requiring extensive and expensive maintenance. Th...

  2. Joint University Program for Air Transportation Research, 1983

    NASA Technical Reports Server (NTRS)

    Morrell, Frederick R. (Compiler)

    1987-01-01

    The research conducted during 1983 under the NASA/FAA sponsored Joint University Program for Air Transportation Research is summarized. The material was presented at a conference held at the Federal Aviation Administration Technical Center, Altantic City, New Jersey, December 16, 1983. The Joint University Program is a coordinated set of three grants sponsored by NASA Langley Research Center and the Federal Aviation Administration, one each with the Massachusetts Institute of Technology, Ohio University, and Princeton University. Completed works, status reports, and bibliographies are presented for research topics, which include navigation, guidance, control, and display concepts. An overview of the year's activities for each of the universities is also presented.

  3. Goddard Technology Efforts to Improve Space Borne Laser Reliability

    NASA Technical Reports Server (NTRS)

    Heaps, William S.

    2006-01-01

    In an effort to reduce the risk, perceived and actual, of employing instruments containing space borne lasers NASA initiated the Laser Risk Reduction Program (LRRP) in 2001. This program managed jointly by NASA Langley and NASA Goddard and employing lasers researchers from government, university and industrial labs is nearing the conclusion of its planned 5 year duration. This paper will describe some of the efforts and results obtained by the Goddard half of the program.

  4. Periprosthetic Joint Infections: Clinical and Bench Research

    PubMed Central

    Legout, Laurence; Senneville, Eric

    2013-01-01

    Prosthetic joint infection is a devastating complication with high morbidity and substantial cost. The incidence is low but probably underestimated. Despite a significant basic and clinical research in this field, many questions concerning the definition of prosthetic infection as well the diagnosis and the management of these infections remained unanswered. We review the current literature about the new diagnostic methods, the management and the prevention of prosthetic joint infections. PMID:24288493

  5. Ohio Route 50 joint sealant experiment : research implementation plan.

    DOT National Transportation Integrated Search

    2005-05-01

    Research in the state of Wisconsin over the past forty years has found no noticeable difference in : performance between jointed concrete pavement (JCP) constructed with a sealed contraction joint and : JCP constructed with a single, narrow, unsealed...

  6. Joint University Program for Air Transportation Research, 1988-1989

    NASA Technical Reports Server (NTRS)

    Morrell, Frederick R. (Compiler)

    1990-01-01

    The research conducted during 1988 to 1989 under the NASA/FAA-sponsored Joint University Program for Air Transportation Research is summarized. The Joint University Program is a coordinated set of three grants sponsored by NASA Langley Research Center and the Federal Aviation Administration, one each with the Massachusetts Institute of Technology, Ohio University, and Princeton University. Completed works, status reports, and annotated bibliographies are presented for research topics, which include computer science, guidance and control theory and practice, aircraft performance, flight dynamics, and applied experimental psychology. An overview of the year's activities for each university is also presented.

  7. Quiet Short-Haul Research Aircraft Joint Navy/NASA Sea Trials

    NASA Technical Reports Server (NTRS)

    Queen, S.; Cochrane, J.

    1982-01-01

    The Quiet Short-Haul Research Aircraft (QSRA) is a flight facility which Ames Research Center is using to conduct a broad program of terminal area and low-speed, propulsive-life flight research. A joint Navy/NASA flight research program used the QSRA to investigate the application of advanced propulsive-lift technology to the naval aircraft-carrier environment. Flight performance of the QSRA is presented together with the results or the joint Navy/NASA flight program. During the joint program, the QSRA operated aboard the USS Kitty Hawk for 4 days, during which numerous unarrested landings and free deck takeoffs were accomplished. These operations demonstrated that a large aircraft incorporating upper-surface-blowing, propulsive-life technology can be operated in the aircraft-carrier environment without any unusual problems.

  8. Spacecraft environmental interactions: A joint Air Force and NASA research and technology program

    NASA Technical Reports Server (NTRS)

    Pike, C. P.; Purvis, C. K.; Hudson, W. R.

    1985-01-01

    A joint Air Force/NASA comprehensive research and technology program on spacecraft environmental interactions to develop technology to control interactions between large spacecraft systems and the charged-particle environment of space is described. This technology will support NASA/Department of Defense operations of the shuttle/IUS, shuttle/Centaur, and the force application and surveillance and detection missions, planning for transatmospheric vehicles and the NASA space station, and the AFSC military space system technology model. The program consists of combined contractual and in-house efforts aimed at understanding spacecraft environmental interaction phenomena and relating results of ground-based tests to space conditions. A concerted effort is being made to identify project-related environmental interactions of concern. The basic properties of materials are being investigated to develop or modify the materials as needed. A group simulation investigation is evaluating basic plasma interaction phenomena to provide inputs to the analytical modeling investigation. Systems performance is being evaluated by both groundbased tests and analysis.

  9. Public priorities for joint pain research: results from a general population survey

    PubMed Central

    Carter, Pam; Ong, Bie Nio; Bedson, John; Jordan, Kelvin P.; Jinks, Clare

    2012-01-01

    Objective. We aimed to identify the priorities for joint pain research from a large general population survey and identify characteristics associated with these priorities. Methods. A question about research priorities was developed in collaboration with the Arthritis Research UK Primary Care Centre’s Research Users’ Group. The question was embedded in a postal survey to an existing cohort of adults with self-reported joint pain, aged ≥56 years, in North Staffordshire. Respondents were asked to rank their top three priorities for research. Factor mixture modelling was used to determine subgroups of priorities. Results. In all, 1756 (88%) people responded to the survey. Of these, 1356 (77%) gave three priorities for research. Keeping active was rated the top priority by 38%, followed by research around joint replacement (9%) and diet/weight loss (9%). Two clusters of people were identified: 62% preferred lifestyle/self-management topics (e.g. keeping active, weight loss) and 38% preferred medical intervention topics (e.g. joint replacement, tablets). Those who preferred the medical options tended to be older and have hip or foot pain. Conclusion. This study has provided population data on priorities for joint pain research expressed by a large cohort of older people who report joint pain. The most popular topics for research were linked to lifestyle and self-management opportunities. Pharmaceutical and invasive interventions, despite being common topics of research, are of less importance to these respondents than non-medical topics. Specific research questions will be generated from this study with collaboration of the patient’s group. PMID:22886341

  10. Group-effort Applied Research: Expanding Opportunities for Undergraduate Research through Original, Class-Based Research Projects

    ERIC Educational Resources Information Center

    Moore, Sean D.; Teter, Ken

    2014-01-01

    Undergraduate research clearly enriches the educational development of participating students, but these experiences are limited by the inherent inefficiency of the standard one student-one mentor model for undergraduate research. Group-effort applied research (GEAR) was developed as a strategy to provide substantial numbers of undergraduates with…

  11. Inequity-aversion and relative kindness intention jointly determine the expenditure of effort in project teams.

    PubMed

    Han, Jiaojie; Rapoport, Amnon; Zhao, Rui

    2017-01-01

    The literature on team cooperation has neglected the effects of relative kindness intention on cooperation, which we measure by comparing the kindness intentions of an agent to her group members to the kindness shown by other members to this same agent. We argue that the agent's emotional reaction to material payoff inequity is not constant, but rather affected by her relative kindness intention. Then, we apply the model to team projects with multiple partners and investigate how inequity-aversion and relative kindness intention jointly influence team cooperation. We first consider the case of homogeneous agents, where their marginal productivity levels and technical capacities are the same, and then consider the case of heterogeneous agents, where their marginal productivity levels and technical capacities are not the same. Our results show that inequity-aversion has no effect on effort expenditure in the former case, but does affect it in the latter case. The consideration of relative kindness intention may impact the agents' optimal cooperative effort expenditure when their technical capacities are different. In addition, it is beneficial for team cooperation, and might not only reduce the negative impact but also enhance the positive impact of inequity-aversion on the agents' effort expenditures.

  12. Inequity-aversion and relative kindness intention jointly determine the expenditure of effort in project teams

    PubMed Central

    Rapoport, Amnon; Zhao, Rui

    2017-01-01

    The literature on team cooperation has neglected the effects of relative kindness intention on cooperation, which we measure by comparing the kindness intentions of an agent to her group members to the kindness shown by other members to this same agent. We argue that the agent’s emotional reaction to material payoff inequity is not constant, but rather affected by her relative kindness intention. Then, we apply the model to team projects with multiple partners and investigate how inequity-aversion and relative kindness intention jointly influence team cooperation. We first consider the case of homogeneous agents, where their marginal productivity levels and technical capacities are the same, and then consider the case of heterogeneous agents, where their marginal productivity levels and technical capacities are not the same. Our results show that inequity-aversion has no effect on effort expenditure in the former case, but does affect it in the latter case. The consideration of relative kindness intention may impact the agents’ optimal cooperative effort expenditure when their technical capacities are different. In addition, it is beneficial for team cooperation, and might not only reduce the negative impact but also enhance the positive impact of inequity-aversion on the agents’ effort expenditures. PMID:28459853

  13. 48 CFR 35.009 - Subcontracting research and development effort.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... ACQUISITION REGULATION SPECIAL CATEGORIES OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING 35.009 Subcontracting research and development effort. Since the selection of R&D contractors is substantially based on... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Subcontracting research...

  14. Case Studies in Describing Scientific Research Efforts as Linked Data

    NASA Astrophysics Data System (ADS)

    Gandara, A.; Villanueva-Rosales, N.; Gates, A.

    2013-12-01

    The Web is growing with numerous scientific resources, prompting increased efforts in information management to consider integration and exchange of scientific resources. Scientists have many options to share scientific resources on the Web; however, existing options provide limited support to scientists in annotating and relating research resources resulting from a scientific research effort. Moreover, there is no systematic approach to documenting scientific research and sharing it on the Web. This research proposes the Collect-Annotate-Refine-Publish (CARP) Methodology as an approach for guiding documentation of scientific research on the Semantic Web as scientific collections. Scientific collections are structured descriptions about scientific research that make scientific results accessible based on context. In addition, scientific collections enhance the Linked Data data space and can be queried by machines. Three case studies were conducted on research efforts at the Cyber-ShARE Research Center of Excellence in order to assess the effectiveness of the methodology to create scientific collections. The case studies exposed the challenges and benefits of leveraging the Semantic Web and Linked Data data space to facilitate access, integration and processing of Web-accessible scientific resources and research documentation. As such, we present the case study findings and lessons learned in documenting scientific research using CARP.

  15. Joint Actinide Shock Physics Experimental Research - JASPER

    ScienceCinema

    None

    2018-01-16

    Commonly known as JASPER the Joint Actinide Shock Physics Experimental Research facility is a two stage light gas gun used to study the behavior of plutonium and other materials under high pressures, temperatures, and strain rates.

  16. [Research progress of three-dimensional printing technique in joint surgery].

    PubMed

    Wang, Fuyou; Ren, Xiang; Yang, Liu

    2014-03-01

    To summarize the application status of three-dimensional (3-D) printing technique in joint surgery and look forward to the future research directions. The recent original articles about the application and research of 3-D printing technique in joint surgery were extensively reviewed and analyzed. In clinical applications, 3-D printing technique can provide "tailored" treatment and custom implants for patients, which helps doctors to perform the complex operations easier and more safely; in fundamental research, tissue engineered scaffolds with desirable external shape and internal organization are easily fabricated with 3-D printing technique, which can meet the demand of cell adherence and proliferation. Even more, cells may be deposited with the biomaterials during the printing. With the development of medical imaging, digital medicine and new materials, 3-D printing technique will have a wider range of applications in joint surgery.

  17. Durability of building joint sealants

    Treesearch

    Christopher C. White; Kar Tean Tan; Donald L. Hunston; R. Sam Williams

    2009-01-01

    Predicting the service life of building joint sealants exposed to service environments in less than real time has been a need of the sealant community for many decades. Despite extensive research efforts to design laboratory accelerated tests to duplicate the failure modes occurring in field exposures, little success has been achieved using conventional durability...

  18. Joint contact forces can be reduced by improving joint moment symmetry in below-knee amputee gait simulations.

    PubMed

    Koelewijn, Anne D; van den Bogert, Antonie J

    2016-09-01

    Despite having a fully functional knee and hip in both legs, asymmetries in joint moments of the knee and hip are often seen in gait of persons with a unilateral transtibial amputation (TTA), possibly resulting in excessive joint loading. We hypothesize that persons with a TTA can walk with more symmetric joint moments at the cost of increased effort or abnormal kinematics. The hypothesis was tested using predictive simulations of gait. Open loop controls of one gait cycle were found by solving an optimization problem that minimizes a combination of walking effort and tracking error in joint angles, ground reaction force and gait cycle duration. A second objective was added to penalize joint moment asymmetry, creating a multi-objective optimization problem. A Pareto front was constructed by changing the weights of the objectives and three solutions were analyzed to study the effect of increasing joint moment symmetry. When the optimization placed more weight on moment symmetry, walking effort increased and kinematics became less normal, confirming the hypothesis. TTA gait improved with a moderate increase in joint moment symmetry. At a small cost of effort and abnormal kinematics, the peak hip extension moment in the intact leg was decreased significantly, and so was the joint contact force in the knee and hip. Additional symmetry required a significant increase in walking effort and the joint contact forces in both hips became significantly higher than in able-bodied gait. Copyright © 2016 Elsevier B.V. All rights reserved.

  19. Joint University Program for Air Transportation Research, 1991-1992

    NASA Technical Reports Server (NTRS)

    Morrell, Frederick R. (Compiler)

    1993-01-01

    This report summarizes the research conducted during the academic year 1991-1992 under the FAA/NASA sponsored Joint University Program for Air Transportation Research. The year end review was held at Ohio University, Athens, Ohio, June 18-19, 1992. The Joint University Program is a coordinated set of three grants sponsored by the Federal Aviation Administration and NASA Langley Research Center, one each with the Massachusetts Institute of Technology (NGL-22-009-640), Ohio University (NGR-36-009-017), and Princeton University (NGL-31-001-252). Completed works, status reports, and annotated bibliographies are presented for research topics, which include navigation, guidance and control theory and practice, intelligent flight control, flight dynamics, human factors, and air traffic control processes. An overview of the year's activities for each university is also presented.

  20. Integrating Quantitative and Qualitative Results in Health Science Mixed Methods Research Through Joint Displays.

    PubMed

    Guetterman, Timothy C; Fetters, Michael D; Creswell, John W

    2015-11-01

    Mixed methods research is becoming an important methodology to investigate complex health-related topics, yet the meaningful integration of qualitative and quantitative data remains elusive and needs further development. A promising innovation to facilitate integration is the use of visual joint displays that bring data together visually to draw out new insights. The purpose of this study was to identify exemplar joint displays by analyzing the various types of joint displays being used in published articles. We searched for empirical articles that included joint displays in 3 journals that publish state-of-the-art mixed methods research. We analyzed each of 19 identified joint displays to extract the type of display, mixed methods design, purpose, rationale, qualitative and quantitative data sources, integration approaches, and analytic strategies. Our analysis focused on what each display communicated and its representation of mixed methods analysis. The most prevalent types of joint displays were statistics-by-themes and side-by-side comparisons. Innovative joint displays connected findings to theoretical frameworks or recommendations. Researchers used joint displays for convergent, explanatory sequential, exploratory sequential, and intervention designs. We identified exemplars for each of these designs by analyzing the inferences gained through using the joint display. Exemplars represented mixed methods integration, presented integrated results, and yielded new insights. Joint displays appear to provide a structure to discuss the integrated analysis and assist both researchers and readers in understanding how mixed methods provides new insights. We encourage researchers to use joint displays to integrate and represent mixed methods analysis and discuss their value. © 2015 Annals of Family Medicine, Inc.

  1. Integrating Quantitative and Qualitative Results in Health Science Mixed Methods Research Through Joint Displays

    PubMed Central

    Guetterman, Timothy C.; Fetters, Michael D.; Creswell, John W.

    2015-01-01

    PURPOSE Mixed methods research is becoming an important methodology to investigate complex health-related topics, yet the meaningful integration of qualitative and quantitative data remains elusive and needs further development. A promising innovation to facilitate integration is the use of visual joint displays that bring data together visually to draw out new insights. The purpose of this study was to identify exemplar joint displays by analyzing the various types of joint displays being used in published articles. METHODS We searched for empirical articles that included joint displays in 3 journals that publish state-of-the-art mixed methods research. We analyzed each of 19 identified joint displays to extract the type of display, mixed methods design, purpose, rationale, qualitative and quantitative data sources, integration approaches, and analytic strategies. Our analysis focused on what each display communicated and its representation of mixed methods analysis. RESULTS The most prevalent types of joint displays were statistics-by-themes and side-by-side comparisons. Innovative joint displays connected findings to theoretical frameworks or recommendations. Researchers used joint displays for convergent, explanatory sequential, exploratory sequential, and intervention designs. We identified exemplars for each of these designs by analyzing the inferences gained through using the joint display. Exemplars represented mixed methods integration, presented integrated results, and yielded new insights. CONCLUSIONS Joint displays appear to provide a structure to discuss the integrated analysis and assist both researchers and readers in understanding how mixed methods provides new insights. We encourage researchers to use joint displays to integrate and represent mixed methods analysis and discuss their value. PMID:26553895

  2. Systematic Dissemination of Research and Development Program Improvement Efforts.

    ERIC Educational Resources Information Center

    Sanders, Carol S.

    A systematic approach to disseminaton of vocational education research and development program improvement efforts is comprehensive, effective, and efficient. Systematic dissemination is a prerequisite link to assessing impact of research and development--for program improvement to occur, successful dissemination is crucial. A systematic approach…

  3. Ultrasound-Guided Steroid Injection of the Pisotriquetral Joint: A Multidisciplinary Effort.

    PubMed

    Brose, Steven W; Montfort, Janel; Gustafson, Kenneth J; Mittebrun, Ionica; Gauriloff, Samantha; Mosher, Mary; Bourbeau, Dennis J

    2017-12-01

    From the perspective of a multidisciplinary team, the authors describe the first reported use of ultrasound guidance for steroid injection into the pisotriquetral joint to relieve wrist pain of a person with spinal cord injury undergoing acute inpatient rehabilitation. Musculoskeletal ultrasound guidance was used to improve the accuracy of a corticosteroid injection of the pisotriquetral joint and the basal thumb in a 70-year-old man with paraplegia experiencing multifocal degenerative wrist pain. There was no bleeding or bruising after the injections, and the patient reported complete pain resolution 1 wk after the injections, which continued for over 1 yr. A multidisciplinary team was key in diagnosis, selection of treatment, and evaluation of treatment effect. Corticosteroid injection of the pisotriquetral joint under ultrasound guidance can be used as a treatment modality for managing wrist pain stemming from that joint. Further investigation and studies evaluating the use of ultrasound versus other imaging modalities for injection of the wrist are indicated.

  4. Future Research Opportunities in Peri-Prosthetic Joint Infection Prevention.

    PubMed

    Berbari, Elie; Segreti, John; Parvizi, Javad; Berríos-Torres, Sandra I

    Peri-prosthetic joint infection (PJI) is a serious complication of prosthetic joint arthroplasty. A better understanding and reversal of modifiable risk factors may lead to a reduction in the incidence of incisional (superficial and deep) and organ/space (e.g., PJI) surgical site infections (SSI). Recently, the Centers for Disease Control and Prevention (CDC) and the Healthcare Infection Control Practices Advisory Committee (HICPAC) published the Guideline for Prevention of Surgical Site Infection. This targeted update applies evidence-based methodology in drafting recommendations for potential strategies to reduce the risk of SSI both across surgical procedures and specifically in prosthetic joint arthroplasty. A panel of PJI content experts identified nine PJI prevention research opportunities based on both evidence gaps identified through the guideline development process (transfusion, immunosuppressive therapy, anticoagulation, orthopedic space suit, and biofilm) and expert opinion (anesthesia, operative room environment, glycemic control, and Staphylococcus aureus nasal screening and decolonization. This article offers a road map for PJI prevention research.

  5. Research on Joint Parameter Inversion for an Integrated Underground Displacement 3D Measuring Sensor

    PubMed Central

    Shentu, Nanying; Qiu, Guohua; Li, Qing; Tong, Renyuan; Shentu, Nankai; Wang, Yanjie

    2015-01-01

    Underground displacement monitoring is a key means to monitor and evaluate geological disasters and geotechnical projects. There exist few practical instruments able to monitor subsurface horizontal and vertical displacements simultaneously due to monitoring invisibility and complexity. A novel underground displacement 3D measuring sensor had been proposed in our previous studies, and great efforts have been taken in the basic theoretical research of underground displacement sensing and measuring characteristics by virtue of modeling, simulation and experiments. This paper presents an innovative underground displacement joint inversion method by mixing a specific forward modeling approach with an approximate optimization inversion procedure. It can realize a joint inversion of underground horizontal displacement and vertical displacement for the proposed 3D sensor. Comparative studies have been conducted between the measured and inversed parameters of underground horizontal and vertical displacements under a variety of experimental and inverse conditions. The results showed that when experimentally measured horizontal displacements and vertical displacements are both varied within 0 ~ 30 mm, horizontal displacement and vertical displacement inversion discrepancies are generally less than 3 mm and 1 mm, respectively, under three kinds of simulated underground displacement monitoring circumstances. This implies that our proposed underground displacement joint inversion method is robust and efficient to predict the measuring values of underground horizontal and vertical displacements for the proposed sensor. PMID:25871714

  6. Research on joint parameter inversion for an integrated underground displacement 3D measuring sensor.

    PubMed

    Shentu, Nanying; Qiu, Guohua; Li, Qing; Tong, Renyuan; Shentu, Nankai; Wang, Yanjie

    2015-04-13

    Underground displacement monitoring is a key means to monitor and evaluate geological disasters and geotechnical projects. There exist few practical instruments able to monitor subsurface horizontal and vertical displacements simultaneously due to monitoring invisibility and complexity. A novel underground displacement 3D measuring sensor had been proposed in our previous studies, and great efforts have been taken in the basic theoretical research of underground displacement sensing and measuring characteristics by virtue of modeling, simulation and experiments. This paper presents an innovative underground displacement joint inversion method by mixing a specific forward modeling approach with an approximate optimization inversion procedure. It can realize a joint inversion of underground horizontal displacement and vertical displacement for the proposed 3D sensor. Comparative studies have been conducted between the measured and inversed parameters of underground horizontal and vertical displacements under a variety of experimental and inverse conditions. The results showed that when experimentally measured horizontal displacements and vertical displacements are both varied within 0~30 mm, horizontal displacement and vertical displacement inversion discrepancies are generally less than 3 mm and 1 mm, respectively, under three kinds of simulated underground displacement monitoring circumstances. This implies that our proposed underground displacement joint inversion method is robust and efficient to predict the measuring values of underground horizontal and vertical displacements for the proposed sensor.

  7. Simulation and Experiment Research on Fatigue Life of High Pressure Air Pipeline Joint

    NASA Astrophysics Data System (ADS)

    Shang, Jin; Xie, Jianghui; Yu, Jian; Zhang, Deman

    2017-12-01

    High pressure air pipeline joint is important part of high pressure air system, whose reliability is related to the safety and stability of the system. This thesis developed a new type-high pressure air pipeline joint, carried out dynamics research on CB316-1995 and new type-high pressure air pipeline joint with finite element method, deeply analysed the join forms of different design schemes and effect of materials on stress, tightening torque and fatigue life of joint. Research team set up vibration/pulse test bench, carried out joint fatigue life contrast test. The result shows: the maximum stress of the joint is inverted in the inner side of the outer sleeve nut, which is consistent with the failure mode of the crack on the outer sleeve nut in practice. Simulation and experiment of fatigue life and tightening torque of new type-high pressure air pipeline joint are better than CB316-1995 joint.

  8. Tobacco industry efforts to undermine policy-relevant research.

    PubMed

    Landman, Anne; Glantz, Stanton A

    2009-01-01

    The tobacco industry, working through third parties to prevent policy-relevant research that adversely affected it between 1988 and 1998, used coordinated, well-funded strategies in repeated attempts to silence tobacco researcher Stanton A. Glantz. Tactics included advertising, litigation, and attempts to have the US Congress cut off the researcher's National Cancer Institute funding. Efforts like these can influence the policymaking process by silencing opposing voices and discouraging other scientists from doing work that may expose them to tobacco industry attacks. The support of highly credible public health organizations and of researchers' employers is crucial to the continued advancement of public health.

  9. Correlates of Research Effort in Carnivores: Body Size, Range Size and Diet Matter

    PubMed Central

    Brooke, Zoe M.; Bielby, Jon; Nambiar, Kate; Carbone, Chris

    2014-01-01

    Given the budgetary restrictions on scientific research and the increasing need to better inform conservation actions, it is important to identify the patterns and causes of biases in research effort. We combine bibliometric information from a literature review of almost 16,500 peer-reviewed publications on a well-known group of 286 species, the Order Carnivora, with global datasets on species' life history and ecological traits to explore patterns in research effort. Our study explores how species' characteristics influenced the degree to which they were studied (measured as the number of publications). We identified a wide variation in intensity of research effort at both Family and Species levels, with some of the least studied being those which may need protection in future. Our findings hint at the complex role of human perspectives in setting research agendas. We found that better-studied species tended to be large-bodied and have a large geographic range whilst omnivory had a negative relationship with research effort. IUCN threat status did not exhibit a strong relationship with research effort which suggests that the conservation needs of individual species are not major drivers of research interest. This work is the first to use a combination of bibliometric analysis and biological data to quantify and interpret gaps in research knowledge across an entire Order. Our results could be combined with other resources, such as Biodiversity Action Plans, to prioritise and co-ordinate future research effort, whilst our methods can be applied across many scientific disciplines to describe knowledge gaps. PMID:24695422

  10. Summary of Work for Joint Research Interchanges with DARWIN Integrated Product Team

    NASA Technical Reports Server (NTRS)

    Hesselink, Lambertus

    1999-01-01

    The intent of Stanford University's SciVis group is to develop technologies that enabled comparative analysis and visualization techniques for simulated and experimental flow fields. These techniques would then be made available un- der the Joint Research Interchange for potential injection into the DARWIN Workspace Environment (DWE). In the past, we have focused on techniques that exploited feature based comparisons such as shock and vortex extractions. Our current research effort focuses on finding a quantitative comparison of general vector fields based on topological features. Since the method relies on topological information, grid matching an@ vector alignment is not needed in the comparison. This is often a problem with many data comparison techniques. In addition, since only topology based information is stored and compared for each field, there is a significant compression of information that enables large databases to be quickly searched. This report will briefly (1) describe current technologies in the area of comparison techniques, (2) will describe the theory of our new method and finally (3) summarize a few of the results.

  11. A Semantic Web-Based Methodology for Describing Scientific Research Efforts

    ERIC Educational Resources Information Center

    Gandara, Aida

    2013-01-01

    Scientists produce research resources that are useful to future research and innovative efforts. In a typical scientific scenario, the results created by a collaborative team often include numerous artifacts, observations and relationships relevant to research findings, such as programs that generate data, parameters that impact outputs, workflows…

  12. Joint pricing, inventory, and preservation decisions for deteriorating items with stochastic demand and promotional efforts

    NASA Astrophysics Data System (ADS)

    Soni, Hardik N.; Chauhan, Ashaba D.

    2018-03-01

    This study models a joint pricing, inventory, and preservation decision-making problem for deteriorating items subject to stochastic demand and promotional effort. The generalized price-dependent stochastic demand, time proportional deterioration, and partial backlogging rates are used to model the inventory system. The objective is to find the optimal pricing, replenishment, and preservation technology investment strategies while maximizing the total profit per unit time. Based on the partial backlogging and lost sale cases, we first deduce the criterion for optimal replenishment schedules for any given price and technology investment cost. Second, we show that, respectively, total profit per time unit is concave function of price and preservation technology cost. At the end, some numerical examples and the results of a sensitivity analysis are used to illustrate the features of the proposed model.

  13. Longitudinal joint treatment.

    DOT National Transportation Integrated Search

    2006-03-01

    Maine highways have been showing signs of longitudinal joint failure for a number of years. In an effort : to reduce the amount of joint failures the Maine Department of Transportation (MDOT) is currently : evaluating two projects. One project is mon...

  14. Physics Education Research efforts to promote diversity: Challenges and opportunities

    NASA Astrophysics Data System (ADS)

    Brahmia, Suzanne

    2015-04-01

    We begin this talk with a brief description of the gender and ethnic diversity of the physics community. We then discuss several current efforts within Physics Education Research that have the potential to further our understanding of issues surrounding underrepresentation. These efforts include research into (1) the role of community and strategies for developing effective communities; (2) physics identity and self-efficacy; (3) the affordances that students from underrepresented groups bring to physics learning; (4) socioeconomics and its impact on mathematization. One of the challenges to conducting this research is the relatively small proportion of underrepresented minority students in current physics classes, and the small number of women in physics and engineering majors. In collaboration with Stephen Kanim, New Mexico State University.

  15. 76 FR 1212 - Joint Biomedical Laboratory Research and Development and Clinical Science Research and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-07

    ... DEPARTMENT OF VETERANS AFFAIRS Joint Biomedical Laboratory Research and Development and Clinical Science Research and Development Services Scientific Merit Review Board Panel for Eligibility; Notice of Meeting The Department of Veterans Affairs (VA) gives notice under the Public Law 92-463 (Federal Advisory...

  16. 75 FR 57833 - Joint Biomedical Laboratory Research and Development and Clinical Science Research and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-22

    ... DEPARTMENT OF VETERANS AFFAIRS Joint Biomedical Laboratory Research and Development and Clinical Science Research and Development Services Scientific Merit Review Board; Notice of Meetings The Department of Veterans Affairs gives notice under the Public Law 92-463 (Federal Advisory Committee Act) that...

  17. 76 FR 66367 - Joint Biomedical Laboratory Research and Development and Clinical Science Research and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-26

    ... DEPARTMENT OF VETERANS AFFAIRS Joint Biomedical Laboratory Research and Development and Clinical Science Research and Development Services Scientific Merit Review Board; Notice of Meetings The Department of Veterans Affairs gives notice under the Public Law 92-463 (Federal Advisory Committee Act) that...

  18. 77 FR 26069 - Joint Biomedical Laboratory Research and Development and Clinical Science Research and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-02

    ... DEPARTMENT OF VETERANS AFFAIRS Joint Biomedical Laboratory Research and Development and Clinical Science Research and Development Services Scientific Merit Review Board, Notice of Meeting Amendment The Department of Veterans Affairs (VA) gives notice under the Public Law 92-463 (Federal Advisory Committee Act...

  19. 76 FR 79273 - Joint Biomedical Laboratory Research and Development and Clinical Science Research and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-21

    ... DEPARTMENT OF VETERANS AFFAIRS Joint Biomedical Laboratory Research and Development and Clinical Science Research and Development Services Scientific Merit Review Board Panel for Eligibility, Notice of Meeting The Department of Veterans Affairs (VA) gives notice under Public Law 92-463 (Federal Advisory...

  20. 78 FR 28292 - Joint Biomedical Laboratory Research and Development and Clinical Science Research and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-14

    ... DEPARTMENT OF VETERANS AFFAIRS Joint Biomedical Laboratory Research and Development and Clinical Science Research and Development Services Scientific Merit Review Board; Notice of Meetings; Amendment The Department of Veterans Affairs (VA) gives notice under the Federal Advisory Committee Act, 5 U.S.C. App...

  1. FAA/NASA Joint University Program for Air Transportation Research, 1992-1993

    NASA Technical Reports Server (NTRS)

    Morrell, Frederick R. (Compiler)

    1994-01-01

    The research conducted during the academic year 1992-1993 under the FAA/NASA sponsored Joint University Program for Air Transportation Research is summarized. The year end review was held at Ohio University, Athens, Ohio, 17-18 June 1993. The Joint University Program is a coordinated set of three grants sponsored by the Federal Aviation Administration and NASA Langley Research Center, one each with the Massachusetts Institute of Technology, Ohio University, and Princeton University. Completed works, status reports, and annotated bibliographies are presented for research topics, which include navigation, guidance, and control theory and practice, aircraft performance, human factors and air traffic management. An overview of the year's activities for each university is also presented.

  2. Tobacco Industry Efforts to Undermine Policy-Relevant Research

    PubMed Central

    Landman, Anne

    2009-01-01

    The tobacco industry, working through third parties to prevent policy-relevant research that adversely affected it between 1988 and 1998, used coordinated, well-funded strategies in repeated attempts to silence tobacco researcher Stanton A. Glantz. Tactics included advertising, litigation, and attempts to have the US Congress cut off the researcher's National Cancer Institute funding. Efforts like these can influence the policymaking process by silencing opposing voices and discouraging other scientists from doing work that may expose them to tobacco industry attacks. The support of highly credible public health organizations and of researchers’ employers is crucial to the continued advancement of public health. PMID:19008508

  3. University Research and Development Activities: The Federal Income Tax Consequences of Research Contracts, Research Subsidiaries and Joint Ventures.

    ERIC Educational Resources Information Center

    Kertz, Consuelo Lauda; Hasson, James K., Jr.

    1986-01-01

    Features of the federal income tax law applying to income received from commercially funded university-based scientific research and development activities are discussed, including: industry-sponsored research contracts, separately incorporated entities, partnerships and joint ventures, subsidiaries and unrelated income consequences of…

  4. Joint University Program for Air Transportation Research, 1989-1990

    NASA Technical Reports Server (NTRS)

    Morrell, Frederick R. (Compiler)

    1990-01-01

    Research conducted during the academic year 1989-90 under the NASA/FAA sponsored Joint University Program for Air Transportation research is discussed. Completed works, status reports and annotated bibliographies are presented for research topics, which include navigation, guidance and control theory and practice, aircraft performance, human factors, and expert systems concepts applied to airport operations. An overview of the year's activities for each university is also presented.

  5. What predicts dissemination efforts among public health researchers in the United States?

    PubMed

    Tabak, Rachel G; Stamatakis, Katherine A; Jacobs, Julie A; Brownson, Ross C

    2014-01-01

    We identified factors related to dissemination efforts by researchers to non-research audiences to reduce the gap between research generation and uptake in public health practice. We conducted a cross-sectional study of 266 researchers at universities, the National Institutes of Health (NIH), and CDC. We identified scientists using a search of public health journals and lists from government-sponsored research. The scientists completed a 35-item online survey in 2012. Using multivariable logistic regression, we compared self-rated effort to disseminate findings to non-research audiences (excellent/good vs. poor) across predictor variables in three categories: perceptions or reasons to disseminate, perceived expectation by employer/funders, and professional training and experience. One-third of researchers rated their dissemination efforts as poor. Many factors were significantly related to whether a researcher rated him/herself as excellent/good, including obligation to disseminate findings (odds ratio [OR] = 2.7, 95% confidence interval [CI] 1.1, 6.8), dissemination important for their department (OR=2.3, 95% CI 1.2, 4.5), dissemination expected by employer (OR=2.0, 95% CI 1.2, 3.2) or by funder (OR=2.1, 95% CI 1.3, 3.2), previous work in a practice/policy setting (OR=4.4, 95% CI 2.1, 9.3), and university researchers with Prevention Research Center affiliation vs. NIH researchers (OR=4.7, 95% CI 1.4, 15.7). With all variables in the model, dissemination expected by funder (OR=2.0, 95% CI 1.2, 3.1) and previous work in a practice/policy setting (OR=3.5, OR 1.7, 7.1) remained significant. These findings support the need for structural changes to the system, including funding agency priorities and participation of researchers in practice- and policy-based experiences, which may enhance efforts to disseminate by researchers.

  6. Brandon Research, Inc. Orthopedic Implant Cooperative Research and Development Agreement (CRADA) Final Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Freeman, W.R.

    1999-04-22

    The project was a joint research effort between the U. S. Department of Energy's (DOE) Kansas City Plant (KCP) and Brandon Research, Inc. to develop ways to improve implants used for orthopedic surgery for joint replacement. The primary product produced by this study is design information, which may be used to develop implants that will improve long-term fixation and durability in the host bone environment.

  7. Experimental Investigation of Solder Joint Defect Formation and Mitigation in Reduced-Gravity Environments

    NASA Technical Reports Server (NTRS)

    Watson, J. Kevin; Struk, Peter M.; Pettegrew, RIchard D.; Downs, Robert S.

    2006-01-01

    This paper documents a research effort on reduced gravity soldering of plated through hole joints which was conducted jointly by the National Center for Space Exploration Research, NASA Glenn Research Center, and NASA Johnson Space Center. Significant increases in joint porosity and changes in external geometry were observed in joints produced in reduced gravity as compared to normal gravity. Multiple techniques for mitigating the observed increase in porosity were tried, including several combinations of flux and solder application techniques, and demoisturizing the circuit board prior to soldering. Results were consistent with the hypothesis that the source of the porosity is a combination of both trapped moisture in the circuit board itself, as well as vaporized flux that is trapped in the molten solder. Other topics investigated include correlation of visual inspection results with joint porosity, pore size measurements, limited pressure effects (0.08 MPa - 0.1 MPa) on the size and number of pores, and joint cooling rate.

  8. Closing the Yield Gap of Sugar Beet in the Netherlands-A Joint Effort.

    PubMed

    Hanse, Bram; Tijink, Frans G J; Maassen, Jurgen; van Swaaij, Noud

    2018-01-01

    tested, and implemented in growers practices. The joint efforts of sugar industry, sugar beet research and growers resulted in a raise in sugar yield from 10.6 t/ha in 2002-2006 to 13.8 t/ha in 2012-2016.

  9. Summary of Work for Joint Research Interchanges with DARWIN Integrated Product Team 1998

    NASA Technical Reports Server (NTRS)

    Hesselink, Lambertus

    1999-01-01

    The intent of Stanford University's SciVis group is to develop technologies that enabled comparative analysis and visualization techniques for simulated and experimental flow fields. These techniques would then be made available under the Joint Research Interchange for potential injection into the DARWIN Workspace Environment (DWE). In the past, we have focused on techniques that exploited feature based comparisons such as shock and vortex extractions. Our current research effort focuses on finding a quantitative comparison of general vector fields based on topological features. Since the method relies on topological information, grid matching and vector alignment is not needed in the comparison. This is often a problem with many data comparison techniques. In addition, since only topology based information is stored and compared for each field, there is a significant compression of information that enables large databases to be quickly searched. This report will briefly (1) describe current technologies in the area of comparison techniques, (2) will describe the theory of our new method and finally (3) summarize a few of the results.

  10. Researchers Rebuild their Effort to Rebuild the Internet

    ERIC Educational Resources Information Center

    Young, Jeffrey R.

    2008-01-01

    Reinveting the Internet is not easy. Researchers working on a federally supported effort to design a replacement recently had to go back to the drawing board. They now think the best way to do it is to try several "best ways" instead of searching for just one--and to invite help from social scientists rather than just self-described computer…

  11. Research into automatic recognition of joints in human symmetrical movements

    NASA Astrophysics Data System (ADS)

    Fan, Yifang; Li, Zhiyu

    2008-03-01

    High speed photography is a major means of collecting data from human body movement. It enables the automatic identification of joints, which brings great significance to the research, treatment and recovery of injuries, the analysis to the diagnosis of sport techniques and the ergonomics. According to the features that when the adjacent joints of human body are in planetary motion, their distance remains the same, and according to the human body joint movement laws (such as the territory of the articular anatomy and the kinematic features), a new approach is introduced to process the image thresholding of joints filmed by the high speed camera, to automatically identify the joints and to automatically trace the joint points (by labeling markers at the joints). Based upon the closure of marking points, automatic identification can be achieved through thresholding treatment. Due to the screening frequency and the laws of human segment movement, when the marking points have been initialized, their automatic tracking can be achieved with the progressive sequential images.Then the testing results, the data from three-dimensional force platform and the characteristics that human body segment will only rotate around the closer ending segment when the segment has no boding force and only valid to the conservative force all tell that after being analyzed kinematically, the approach is approved to be valid.

  12. Joint Efforts Towards European HF Radar Integration

    NASA Astrophysics Data System (ADS)

    Rubio, A.; Mader, J.; Griffa, A.; Mantovani, C.; Corgnati, L.; Novellino, A.; Schulz-Stellenfleth, J.; Quentin, C.; Wyatt, L.; Ruiz, M. I.; Lorente, P.; Hartnett, M.; Gorringe, P.

    2016-12-01

    During the past two years, significant steps have been made in Europe for achieving the needed accessibility to High Frequency Radar (HFR) data for a pan-European use. Since 2015, EuroGOOS Ocean Observing Task Teams (TT), such as HFR TT, are operational networks of observing platforms. The main goal is on the harmonization of systems requirements, systems design, data quality, improvement and proof of the readiness and standardization of HFR data access and tools. Particular attention is being paid by HFR TT to converge from different projects and programs toward those common objectives. First, JERICO-NEXT (Joint European Research Infrastructure network for Coastal Observatory - Novel European eXpertise for coastal observaTories, H2020 2015 Programme) will contribute on describing the status of the European network, on seeking harmonization through exchange of best practices and standardization, on developing and giving access to quality control procedures and new products, and finally on demonstrating the use of such technology in the general scientific strategy focused by the Coastal Observatory. Then, EMODnet (European Marine Observation and Data Network) Physics started to assemble HF radar metadata and data products within Europe in a uniform way. This long term program is providing a combined array of services and functionalities to users for obtaining free of charge data, meta-data and data products on the physical conditions of European sea basins and oceans. Additionally, the Copernicus Marine Environment Monitoring Service (CMEMS) delivers from 2015 a core information service to any user related to 4 areas of benefits: Maritime Safety, Coastal and Marine Environment, Marine Resources, and Weather, Seasonal Forecasting and Climate activities. INCREASE (Innovation and Networking for the integration of Coastal Radars into EuropeAn marine SErvices - CMEMS Service Evolution 2016) will set the necessary developments towards the integration of existing European

  13. FAA/NASA Joint University Program for Air Transportation Research: 1993-1994

    NASA Technical Reports Server (NTRS)

    Hueschen, Richard M. (Compiler)

    1995-01-01

    This report summarizes the research conducted during the academic year 1993-1994 under the NASA/FAA sponsored Joint University Program for Air Transportation Research. The year end review was held at Ohio University, Athens, Ohio, July 14-15, 1994. The Joint University Program is a coordinated set of three grants sponsored by NASA Langley Research Center and the Federal Aviation Administration, one each with the Massachusetts Institute of Technology (NGL-22-009-640), Ohio University (NGR-36-009-017), and Princeton University (NGL-31-001-252). Completed works, status reports, and annotated bibliographies are presented for research topics which include navigation, guidance and control theory and practice, aircraft performance, human factors, and expert systems concepts applied to aircraft and airport operations. An overview of the year's activities for each university is also presented.

  14. The Joint NASA/Goddard-University of Maryland Research Program in Charged Particle and High Energy Photon Detector Technology

    NASA Technical Reports Server (NTRS)

    1988-01-01

    Having recognized at an early stage the critical importance of maintaining detector capabilities which utilize state of the art techniques, a joint program was formulated. This program has involved coordination of a broad range of efforts and activities including joint experiments, collaboration in theoretical studies, instrument design, calibrations, and data analysis. Summaries of the progress made to date are presented. A representative bibliography is also included.

  15. Workshop Report: Joint Requirements. Oversight Council Process.

    DTIC Science & Technology

    1996-02-28

    provides media for professional exchange and peer criticism among students, theoreticians, practitioners, and users of military operations research. These... exchange of ideas and methods. involvement in the annual Joint Warfare Inter- Subsequent efforts could include multiple operability Demonstrations (JWID...forums for exchange of ideas at the working level, clear, visible relations but studies and analysis opportunities as well. between the JWCAs need to

  16. A guided tour of current research in synovial joints with reference to wavelet methodology

    NASA Astrophysics Data System (ADS)

    Agarwal, Ruchi; Salimath, C. S.; Alam, Khursheed

    2017-10-01

    Main aim of this article is to provide a comprehensive overview of biomechanical aspects of synovial joints of human body. This can be considered as a part of continued research work carried out by various authors over a period of time. Almost every person once in life time has suffered from joint disease; this has triggered intensive investigation into various biomechanical aspects of synovial joints. This has also resulted into an increase of arthroplasty with introduction to various clinical trials. From last few decades new improvements and ideas for new technologies have been introduced to decrease the incidence of joint problem. In this paper a literature survey of recent advances, developments and recognition of wear and tear of human joint is presented. Wavelet method in Computational fluid dynamics (CFD) is relatively a new research field. This review aims to provide a glimpse of wavelet methodology in CFD. Wavelets methodology has played a vital role in the solution of governing equation of synovial fluid flow in the synovial joints represented by Reynolds equation and its modified version.

  17. United States Research and Development effort on ITER magnet tasks

    DOE PAGES

    Martovetsky, Nicolai N.; Reierson, Wayne T.

    2011-01-22

    This study presents the status of research and development (R&D) magnet tasks that are being performed in support of the U.S. ITER Project Office (USIPO) commitment to provide a central solenoid assembly and toroidal field conductor for the ITER machine to be constructed in Cadarache, France. The following development tasks are presented: winding development, inlets and outlets development, internal and bus joints development and testing, insulation development and qualification, vacuum-pressure impregnation, bus supports, and intermodule structure and materials characterization.

  18. Korea University Joins the International Efforts in Clinical Proteogenomics Cancer Research | Office of Cancer Clinical Proteomics Research

    Cancer.gov

    The National Cancer Institute's (NCI) Office of Cancer Clinical Proteomics Research, part of the National Institutes of Health, and Korea University (KU) located in The Republic of Korea have signed a Memorandum of Understanding (MOU) in clinical proteogenomics cancer research. The MOU between NCI and KU represents the twenty-ninth institution and eleventh country to join the continued effort of the International Cancer Proteogenome Consortium (ICPC), an effort catalyzed through the vision of the 47th Vice President of the United States Joseph R. Biden, Jr. and the Cancer Moonshot.

  19. Longitudinal joint treatment : construction report.

    DOT National Transportation Integrated Search

    2000-05-01

    Maine highways have been showing signs of longitudinal joint failure for a number of : years. In an effort to reduce the amount of joint failures the Maine Department of : Transportation (MDOT) is currently evaluating two projects. One project is mon...

  20. The special effort processing of FGGE data

    NASA Technical Reports Server (NTRS)

    1983-01-01

    The basic FGGE level IIb data set was enhanced. It focused on removing deficiencies in the objective methods of quality assurance, removing efficiencies in certain types of operationally produced satellite soundings, and removing deficiencies in certain types of operationally produced cloud tracked winds. The Special Effort was a joint NASA-NOAA-University of Wisconsin effort. The University of Wisconsin installed an interactive McIDAS capability on the Amdahl computer at the Goddard Laboratory of Atmospheric Sciences (GLAS) with one interactive video terminal at Goddard and the other at the World Weather Building. With this interactive capability a joint processing effort was undertaken to reprocess certain FGGE data sets. NOAA produced a specially edited data set for the special observing periods (SOPs) of FGGE. NASA produced an enhanced satellite sounding data set for the SOPs while the University of Wisconsin produced an enhanced cloud tracked wind set from the Japanese geostationary satellite images.

  1. Research, public policymaking, and knowledge-translation processes: Canadian efforts to build bridges.

    PubMed

    Lavis, John N

    2006-01-01

    Public policymakers must contend with a particular set of institutional arrangements that govern what can be done to address any given issue, pressure from a variety of interest groups about what they would like to see done to address any given issue, and a range of ideas (including research evidence) about how best to address any given issue. Rarely do processes exist that can get optimally packaged high-quality and high-relevance research evidence into the hands of public policymakers when they most need it, which is often in hours and days, not months and years. In Canada, a variety of efforts have been undertaken to address the factors that have been found to increase the prospects for research use, including the production of systematic reviews that meet the shorter term (but not urgent) needs of public policymakers and encouraging partnerships between researchers and policymakers that allow for their interaction around the tasks of asking and answering relevant questions. Much less progress has been made in making available research evidence to inform the urgent needs of public policymakers and in addressing attitudinal barriers and capacity limitations. In the future, knowledge-translation processes, particularly push efforts and efforts to facilitate user pull, should be undertaken on a sufficiently large scale and with a sufficiently rigorous evaluation so that robust conclusions can be drawn about their effectiveness.

  2. Changes in federal agencies panel: human dimensions research and ecosystem management: policy and research implications for recreation research efforts

    Treesearch

    Alan Ewert

    1995-01-01

    With an increased emphasis being placed on ecosystem management, the importance of Human Dimension Research (HDR) efforts in management and policy formulation are becoming more important. Developing an understanding of the type of management questions and policy needs that can be addressed by human dimension research is becoming increasingly important and timely. This...

  3. [Effort-reward imbalance at work and depression: current research evidence].

    PubMed

    Siegrist, J

    2013-01-01

    In view of highly prevalent stressful conditions in modern working life, in particular increasing work pressure and job insecurity, it is of interest to know whether specific constellations of an adverse psychosocial work environment increase the risk of depressive disorder among employed people. This contribution gives a short overview of current research evidence based on an internationally established work stress model of effort-reward imbalance. Taken together, results from seven prospective epidemiological investigations demonstrate a two-fold elevated relative risk of incident depressive disorder over a mean observation period of 2.7 years among exposed versus non-exposed employees. Additional findings from experimental and quasi-experimental studies point to robust associations of effort-reward imbalance at work with proinflammatory cytokines and markers of reduced immune competence. These latter markers may indicate potential psychobiological pathways. In conclusion, incorporating this new knowledge into medical treatment and preventive efforts seems well justified.

  4. Recent Advances in Tissue Engineering Strategies for the Treatment of Joint Damage.

    PubMed

    Stephenson, Makeda K; Farris, Ashley L; Grayson, Warren L

    2017-08-01

    While the clinical potential of tissue engineering for treating joint damage has yet to be realized, research and commercialization efforts in the field are geared towards overcoming major obstacles to clinical translation, as well as towards achieving engineered grafts that recapitulate the unique structures, function, and physiology of the joint. In this review, we describe recent advances in technologies aimed at obtaining biomaterials, stem cells, and bioreactors that will enable the development of effective tissue-engineered treatments for repairing joint damage. 3D printing of scaffolds is aimed at improving the mechanical structure and microenvironment necessary for bone regeneration within a damaged joint. Advances in our understanding of stem cell biology and cell manufacturing processes are informing translational strategies for the therapeutic use of allogeneic and autologous cells. Finally, bioreactors used in combination with cells and biomaterials are promising strategies for generating large tissue grafts for repairing damaged tissues in pre-clinical models. Together, these advances along with ongoing research directions are making tissue engineering increasingly viable for the treatment of joint damage.

  5. Longitudinal joint treatment : first interim report.

    DOT National Transportation Integrated Search

    2000-11-01

    Maine highways have been showing signs of longitudinal joint failure for a number of : years. In an effort to reduce the amount of joint failures the Maine Department of : Transportation (MDOT) is currently evaluating two projects. One project is mon...

  6. Longitudinal joint treatment : second interim report.

    DOT National Transportation Integrated Search

    2001-09-01

    Maine highways have been showing signs of longitudinal joint failure for a : number of years. In an effort to reduce the amount of joint failures the Maine : Department of Transportation (MDOT) is currently evaluating two projects. One : project is m...

  7. NASA/Drexel program. [research effort in large-scale technical programs management for application to urban problems

    NASA Technical Reports Server (NTRS)

    1973-01-01

    The results are reported of the NASA/Drexel research effort which was conducted in two separate phases. The initial phase stressed exploration of the problem from the point of view of three primary research areas and the building of a multidisciplinary team. The final phase consisted of a clinical demonstration program in which the research associates consulted with the County Executive of New Castle County, Delaware, to aid in solving actual problems confronting the County Government. The three primary research areas of the initial phase are identified as technology, management science, and behavioral science. Five specific projects which made up the research effort are treated separately. A final section contains the conclusions drawn from total research effort as well as from the specific projects.

  8. Inequity responses of monkeys modified by effort.

    PubMed

    van Wolkenten, Megan; Brosnan, Sarah F; de Waal, Frans B M

    2007-11-20

    Without joint benefits, joint actions could never have evolved. Cooperative animals need to monitor closely how large a share they receive relative to their investment toward collective goals. This work documents the sensitivity to reward division in brown, or tufted, capuchin monkeys (Cebus apella). In addition to confirming previous results with a larger subject pool, this work rules out several alternative explanations and adds data on effort sensitivity. Thirteen adult monkeys exchanged tokens for rewards, showing negative reactions to receiving a less-favored reward than their partner. Because their negative reaction could not be attributed to the mere visibility of better rewards (greed hypothesis) nor to having received such rewards in the immediate past (frustration hypothesis), it must have been caused by seeing their partner obtain the better reward. Effort had a major effect in that by far the lowest level of performance in the entire study occurred in subjects required to expend a large effort while at the same time seeing their partner receive a better reward. It is unclear whether this effort-effect was based on comparisons with the partner, but it added significantly to the intensity of the inequity response. These effects are as expected if the inequity response evolved in the context of cooperative survival strategies.

  9. Joint Institute for Nanoscience Annual Report 2004

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Baer, Donald R.; Campbell, Charles

    Due to the inherently interdisciplinary nature of nanoscience and nanotechnology, research in this arena is often significantly enhanced through creative cooperative activities. The Joint Institute for Nanoscience (JIN) is a venture of the University of Washington (UW) and Pacific Northwest National Laboratory (PNNL) to encourage and enhance high impact and high quality nanoscience and nanotechnology research that leverages the strengths and capabilities of both institutions, and to facilitate education in these areas. This report summarizes JIN award activities that took place during fiscal year 2004 and provides a historical list of JIN awardees, their resulting publications, and JIN-related meetings. Majormore » portions of the JIN efforts and resources are dedicated to funding graduate students and postdoctoral research associates to perform research in collaborations jointly directed by PNNL staff scientists and UW professors. JIN fellowships are awarded on the basis of applications that include research proposals. They have been very successful in expanding collaborations between PNNL and UW, which have led to many excellent joint publications and presentations and enhanced the competitiveness of both institutions for external grant funding. JIN-based interactions are playing a significant role in creating new research directions and reshaping existing research programs at both the UW and PNNL. The JIN also co-sponsors workshops on Nanoscale Science and Technology, four of which have been held in Seattle and one in Richland. In addition to involving PNNL staff in various UW nanoscience courses and seminars, a National Science Foundation grant, Development of UW-PNL Collaborative Curriculums in Nano-Science and Technology, has allowed the development of three intensive short courses that are taught by UW faculty, PNNL staff, and faculty from other institutions, including Washington State University, the University of Idaho, Stanford University, and the

  10. Imaging and Analysis of Void-defects in Solder Joints Formed in Reduced Gravity using High-Resolution Computed Tomography

    NASA Technical Reports Server (NTRS)

    Easton, John W.; Struk, Peter M.; Rotella, Anthony

    2008-01-01

    As a part of efforts to develop an electronics repair capability for long duration space missions, techniques and materials for soldering components on a circuit board in reduced gravity must be developed. This paper presents results from testing solder joint formation in low gravity on a NASA Reduced Gravity Research Aircraft. The results presented include joints formed using eutectic tin-lead solder and one of the following fluxes: (1) a no-clean flux core, (2) a rosin flux core, and (3) a solid solder wire with external liquid no-clean flux. The solder joints are analyzed with a computed tomography (CT) technique which imaged the interior of the entire solder joint. This replaced an earlier technique that required the solder joint to be destructively ground down revealing a single plane which was subsequently analyzed. The CT analysis technique is described and results presented with implications for future testing as well as implications for the overall electronics repair effort discussed.

  11. Group-effort applied research: expanding opportunities for undergraduate research through original, class-based research projects.

    PubMed

    Moore, Sean D; Teter, Ken

    2014-01-01

    Undergraduate research clearly enriches the educational development of participating students, but these experiences are limited by the inherent inefficiency of the standard one student-one mentor model for undergraduate research. Group-effort applied research (GEAR) was developed as a strategy to provide substantial numbers of undergraduates with meaningful research experiences. The GEAR curriculum delivers concept-driven lecture material and provides hands-on training in the context of an active research project from the instructor's laboratory. Because GEAR is structured as a class, participating students benefit from intensive, supervised research training that involves a built-in network of peer support and abundant contact with faculty mentors. The class format also ensures a relatively standardized and consistent research experience. Furthermore, meaningful progress toward a research objective can be achieved more readily with GEAR than with the traditional one student-one mentor model of undergraduate research because sporadic mistakes by individuals in the class are overshadowed by the successes of the group as a whole. Three separate GEAR classes involving three distinct research projects have been offered to date. In this article, we provide an overview of the GEAR format and review some of the recurring themes for GEAR instruction. We propose GEAR can serve as a template to expand student opportunities for life science research without sacrificing the quality of the mentored research experience. © 2014 The International Union of Biochemistry and Molecular Biology.

  12. Group-Effort Applied Research (GEAR): Expanding Opportunities for Undergraduate Research Through Original, Class-Based Research Projects

    PubMed Central

    Moore, Sean D.; Teter, Ken

    2014-01-01

    Undergraduate research clearly enriches the educational development of participating students, but these experiences are limited by the inherent inefficiency of the standard one student - one mentor model for undergraduate research. Group-Effort Applied Research (GEAR) was developed as a strategy to provide substantial numbers of undergraduates with meaningful research experiences. The GEAR curriculum delivers concept-driven lecture material and provides hands-on training in the context of an active research project from the instructor's lab. Because GEAR is structured as a class, participating students benefit from intensive, supervised research training that involves a built-in network of peer support and abundant contact with faculty mentors. The class format also ensures a relatively standardized and consistent research experience. Furthermore, meaningful progress toward a research objective can be achieved more readily with GEAR than with the traditional one student - one mentor model of undergraduate research because sporadic mistakes by individuals in the class are overshadowed by the successes of the group as a whole. Three separate GEAR classes involving three distinct research projects have been offered to date. In this paper, we provide an overview of the GEAR format and review some of the recurring themes for GEAR instruction. We propose GEAR can serve as a template to expand student opportunities for life science research without sacrificing the quality of the mentored research experience. PMID:24898007

  13. Design and research on the two-joint mating system of underwater vehicle

    NASA Astrophysics Data System (ADS)

    Zhang, Zhong-lin; Wang, Li-quan

    2013-03-01

    In the 21st century, people have come to the era of ocean science and ocean economy. With the development of ocean science and technology and the thorough research on the ocean, underwater mating technique has been widely used in such fields as sunk ship salvage, deep ocean workstation, submarine lifesaving aid and military affairs. In this paper, researches are made home and abroad on mating technology. Two-joint mating system of underwater vehicle is designed including plane system, three-dimensional assembly system and control system in order to increase the capacity of adapting platform obliquity and adopting rotational skirt scheme. It is clear that the system fits the working space of underwater vehicle passageway and there is no interference phenomenon in assembly design. The finite element model of the system shell and the pressurization of the joint are established. The results of the finite element computing and the pressing test are accordant, and thus it can testify that the shell material meet the need of intension and joint pressurization is reliable. Modeling of the control system is accomplished, and simulation and analysis are made, which can provide directions for the controller design of mating system of underwater vehicles.

  14. 15 CFR 295.23 - Dissolution of joint research and development ventures.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 15 Commerce and Foreign Trade 1 2011-01-01 2011-01-01 false Dissolution of joint research and development ventures. 295.23 Section 295.23 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE NIST EXTRAMURAL...

  15. 15 CFR 295.23 - Dissolution of joint research and development ventures.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 15 Commerce and Foreign Trade 1 2012-01-01 2012-01-01 false Dissolution of joint research and development ventures. 295.23 Section 295.23 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE NIST EXTRAMURAL...

  16. 15 CFR 295.23 - Dissolution of joint research and development ventures.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 15 Commerce and Foreign Trade 1 2014-01-01 2014-01-01 false Dissolution of joint research and development ventures. 295.23 Section 295.23 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE NIST EXTRAMURAL...

  17. 15 CFR 295.23 - Dissolution of joint research and development ventures.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Dissolution of joint research and development ventures. 295.23 Section 295.23 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE NIST EXTRAMURAL...

  18. 15 CFR 295.23 - Dissolution of joint research and development ventures.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 15 Commerce and Foreign Trade 1 2013-01-01 2013-01-01 false Dissolution of joint research and development ventures. 295.23 Section 295.23 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE NIST EXTRAMURAL...

  19. Transmission research activities at NASA Lewis Research Center

    NASA Technical Reports Server (NTRS)

    Lewicki, D. G.

    1990-01-01

    A joint research program, to advance the technology of rotorcraft transmissions, consists of analytical and experimental efforts to achieve the overall goals of reducing transmission weight and noise, while increasing life and reliability. Recent activities in the areas of transmission and related component research are highlighted. Current areas include specific technologies in support of military rotary wing aviation, gearing technology, transmission noise reduction studies, a recent interest in gearbox diagnostics, and advanced transmission system studies. Results of recent activities are presented along with near term research plans.

  20. Importance of joint efforts for balanced process of designing and education

    NASA Astrophysics Data System (ADS)

    Mayorova, V. I.; Bannova, O. K.; Kristiansen, T.-H.; Igritsky, V. A.

    2015-06-01

    This paper discusses importance of a strategic planning and design process when developing long-term space exploration missions both robotic and manned. The discussion begins with reviewing current and/or traditional international perspectives on space development at the American, Russian and European space agencies. Some analogies and comparisons will be drawn upon analysis of several international student collaborative programs: Summer International workshops at the Bauman Moscow State Technical University, International European Summer Space School "Future Space Technologies and Experiments in Space", Summer school at Stuttgart University in Germany. The paper will focus on discussion about optimization of design and planning processes for successful space exploration missions and will highlight importance of the following: understanding connectivity between different levels of human being and machinery; simultaneous mission planning approach; reflections and correlations between disciplines involved in planning and executing space exploration missions; knowledge gained from different disciplines and through cross-applying and re-applying design approaches between variable space related fields of study and research. The conclusions will summarize benefits and complications of applying balanced design approach at all levels of the design process. Analysis of successes and failures of organizational efforts in space endeavors is used as a methodological approach to identify key questions to be researched as they often cause many planning and design processing problems.

  1. Joint document concerning geological studies from 1971 - 1975

    NASA Technical Reports Server (NTRS)

    1977-01-01

    In 1971, a joint Soviet-Americam Working Group on Remote Sensing of the Natural Environment was established. It was organized into a number of discipline panels, one of which was on geology. Membership on this panel came from the Geological Survey of the United States and from the Institute of Geology of the U.S.S.R. Academy of Sciences and Ministry Geology of the U.S.S.R.. During the period 1971-1975, this panel conducted coordinated research in the use of space remote sensing data in the field of geology. A summary of that coordinated research effort is presented.

  2. 75 FR 14190 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-Joint Venture To...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-24

    ... DEPARTMENT OF JUSTICE Antitrust Division Notice Pursuant to the National Cooperative Research and Production Act of 1993--Joint Venture To Perform Project Entitled Robotic Rehabilitation of Aging Water... Cooperative Research and Production Act of 1993, 15 U.S.C. 4301 et sect. (``the Act''), Joint [[Page 14191...

  3. Cold Weather Wind Turbines: A Joint NASA/NSF/DOE Effort in Technology Transfer and Commercialization

    NASA Technical Reports Server (NTRS)

    Flynn, Michael; Bubenheim, David; Chiang, Erick; Goldman, Peter; Kohout, Lisa; Norton, Gary; Kliss, Mark (Technical Monitor)

    1997-01-01

    Renewable energy sources and their integration with other power sources to support remote communities is of interest for Mars applications as well as Earth communities. The National Science Foundation (NSF), NASA, and the Department of Energy (DOE) have been jointly supporting development of a 100 kW cold weather wind turbine through grants and SBIRs independently managed by each agency but coordinated by NASA. The NSF grant addressed issues associated with the South Pole application and a 3 kW direct drive unit is being tested there in anticipation of the 100 kW unit operation. The DOE-NREL contract focused on development of the 100 kW direct drive generator. The NASA SBIR focused on the development of the 100 kW direct drive wind turbine. The success of this effort has required coordination and team involvement of federal agencies and the industrial partners. Designs of the wind turbine and component performance testing results will be presented. Plans for field testing of wind turbines, based on this design, in village energy systems in Alaska and in energy production at the South Pole Station will be discussed. Also included will be a discussion of terrestrial and space use of hybrid energy systems, including renewable energy sources, such as the wind turbine, to support remote communities.

  4. FAA/NASA Joint University Program for Air Transportation Research 1994-1995

    NASA Technical Reports Server (NTRS)

    Remer, J. H.

    1998-01-01

    The Joint University Program for Air Transportation Research (JUP) is a coordinated set of three grants co-sponsored by the Federal Aviation Administration (FAA) and the National Aeronautics and Space Administration (NASA). Under JUP, three institutions: the Massachusetts Institute of Technology, Princeton, and Ohio Universities receive research grants and collaborate with FAA and NASA in defining and performing civil aeronautics research in a multitude of areas. Some of these disciplines are artificial intelligence, control theory, atmospheric hazards, navigation, avionics, human factors, flight dynamics, air traffic management, and electronic communications.

  5. The joint center for energy storage research: A new paradigm for battery research and development

    NASA Astrophysics Data System (ADS)

    Crabtree, George

    2015-03-01

    The Joint Center for Energy Storage Research (JCESR) seeks transformational change in transportation and the electricity grid driven by next generation high performance, low cost electricity storage. To pursue this transformative vision JCESR introduces a new paradigm for battery research: integrating discovery science, battery design, research prototyping and manufacturing collaboration in a single highly interactive organization. This new paradigm will accelerate the pace of discovery and innovation and reduce the time from conceptualization to commercialization. JCESR applies its new paradigm exclusively to beyond-lithium-ion batteries, a vast, rich and largely unexplored frontier. This review presents JCESR's motivation, vision, mission, intended outcomes or legacies and first year accomplishments.

  6. GLOBAL CHANGE RESEARCH NEWS #10: MULTIAGENCY, MULTINATIONAL GLOBAL CHANGE RESEARCH EFFORT IN THE UPPER SAN PEDRO BASIN

    EPA Science Inventory

    This edition reports on a multiagency, multinational global-change research effort that seeks to evaluate the consequences of natural and human-induced changes in semi-arid environments. The Semi-Arid Land-Surface-Atmosphere Program ("SALSA") is focused on the environmentally sen...

  7. Inequity responses of monkeys modified by effort

    PubMed Central

    van Wolkenten, Megan; Brosnan, Sarah F.; de Waal, Frans B. M.

    2007-01-01

    Without joint benefits, joint actions could never have evolved. Cooperative animals need to monitor closely how large a share they receive relative to their investment toward collective goals. This work documents the sensitivity to reward division in brown, or tufted, capuchin monkeys (Cebus apella). In addition to confirming previous results with a larger subject pool, this work rules out several alternative explanations and adds data on effort sensitivity. Thirteen adult monkeys exchanged tokens for rewards, showing negative reactions to receiving a less-favored reward than their partner. Because their negative reaction could not be attributed to the mere visibility of better rewards (greed hypothesis) nor to having received such rewards in the immediate past (frustration hypothesis), it must have been caused by seeing their partner obtain the better reward. Effort had a major effect in that by far the lowest level of performance in the entire study occurred in subjects required to expend a large effort while at the same time seeing their partner receive a better reward. It is unclear whether this effort–effect was based on comparisons with the partner, but it added significantly to the intensity of the inequity response. These effects are as expected if the inequity response evolved in the context of cooperative survival strategies. PMID:18000045

  8. The Joint Space Operations Center Mission System and the Advanced Research, Collaboration, and Application Development Environment Status Update 2016

    NASA Astrophysics Data System (ADS)

    Murray-Krezan, Jeremy; Howard, Samantha; Sabol, Chris; Kim, Richard; Echeverry, Juan

    2016-05-01

    The Joint Space Operations Center (JSpOC) Mission System (JMS) is a service-oriented architecture (SOA) infrastructure with increased process automation and improved tools to enhance Space Situational Awareness (SSA) performed at the US-led JSpOC. The Advanced Research, Collaboration, and Application Development Environment (ARCADE) is a test-bed maintained and operated by the Air Force to (1) serve as a centralized test-bed for all research and development activities related to JMS applications, including algorithm development, data source exposure, service orchestration, and software services, and provide developers reciprocal access to relevant tools and data to accelerate technology development, (2) allow the JMS program to communicate user capability priorities and requirements to developers, (3) provide the JMS program with access to state-of-the-art research, development, and computing capabilities, and (4) support JMS Program Office-led market research efforts by identifying outstanding performers that are available to shepherd into the formal transition process. In this paper we will share with the international remote sensing community some of the recent JMS and ARCADE developments that may contribute to greater SSA at the JSpOC in the future, and share technical areas still in great need.

  9. NASA's Participation in Joint SatOPS Compatibility Efforts 2009-2010

    NASA Technical Reports Server (NTRS)

    Smith, Danford

    2010-01-01

    Many U.S. government organizations build or fly space systems: a) NASA, NOAA, Navy, Air Force, NRO, ORS. Others? b) Through the Joint SatOps Compatibility Committee (JSCC) we have increased the grass-roots interaction between many of these organizations. c) We all deal with many of the same challenges: More rapid deployments, lower budgets; Advancing technologies - frameworks, clouds, virtualization; Evolving concepts - automation, situational awareness, enterprise mngt. Standardization - formal or by common use. There is an inherently governmental role in creating the business case for contractors and commercial product vendors to move in directions beneficial to multiple government space organizations.

  10. Control of joint motion simulators for biomechanical research

    NASA Technical Reports Server (NTRS)

    Colbaugh, R.; Glass, K.

    1992-01-01

    The authors present a hierarchical adaptive algorithm for controlling upper extremity human joint motion simulators. A joint motion simulator is a computer-controlled, electromechanical system which permits the application of forces to the tendons of a human cadaver specimen in such a way that the cadaver joint under study achieves a desired motion in a physiologic manner. The proposed control scheme does not require knowledge of the cadaver specimen dynamic model, and solves on-line the indeterminate problem which arises because human joints typically possess more actuators than degrees of freedom. Computer simulation results are given for an elbow/forearm system and wrist/hand system under hierarchical control. The results demonstrate that any desired normal joint motion can be accurately tracked with the proposed algorithm. These simulation results indicate that the controller resolved the indeterminate problem redundancy in a physiologic manner, and show that the control scheme was robust to parameter uncertainty and to sensor noise.

  11. Joint Commission president outlines top strategic priorities to aid QI efforts.

    PubMed

    2001-06-01

    At the top of the list of strategic priorities at the Joint Commission on Accreditation of Healthcare Organizations (JCAHO) is patient safety. But Dennis O'Leary, MD, president of JCAHO, says his organization faces numerous challenges beyond that, including the value of accreditation itself. According to O'Leary, the underlying issue is that only about 15% of the 150,000 health care entities currently eligible for accreditation are actually accredited.

  12. Forebody/Inlet of the Joint Strike Fighter Tested at Low Speeds

    NASA Technical Reports Server (NTRS)

    Johns, Albert L.

    1998-01-01

    As part of a national cooperative effort to develop a multinational fighter aircraft, a model of a Joint Strike Fighter concept was tested in several NASA Lewis Research Center wind tunnels at low speeds over a range of headwind velocities and model attitudes. This Joint Strike Fighter concept, which is scheduled to go into production in 2005, will greatly improve the range, capability, maneuverability, and survivability of fighter aircraft, and the production program could ultimately be worth $100 billion. The test program was a team effort between Lewis and Lockheed Martin Tactical Aircraft Systems. Testing was completed in September 1997, several weeks ahead of schedule, allowing Lockheed additional time to review the results and analysis data before the next test and resulting in significant cost savings for Lockheed. Several major milestones related to dynamic and steady-state data acquisition and overall model performance were reached during this model test. Results from this program will contribute to both the concept demonstration phase and the production aircraft.

  13. Joint FACET: the Canada-Netherlands initiative to study multisensor data fusion systems

    NASA Astrophysics Data System (ADS)

    Bosse, Eloi; Theil, Arne; Roy, Jean; Huizing, Albert G.; van Aartsen, Simon

    1998-09-01

    This paper presents the progress of a collaborative effort between Canada and The Netherlands in analyzing multi-sensor data fusion systems, e.g. for potential application to their respective frigates. In view of the overlapping interest in studying and comparing applicability and performance and advanced state-of-the-art Multi-Sensor Data FUsion (MSDF) techniques, the two research establishments involved have decided to join their efforts in the development of MSDF testbeds. This resulted in the so-called Joint-FACET, a highly modular and flexible series of applications that is capable of processing both real and synthetic input data. Joint-FACET allows the user to create and edit test scenarios with multiple ships, sensor and targets, generate realistic sensor outputs, and to process these outputs with a variety of MSDF algorithms. These MSDF algorithms can also be tested using typical experimental data collected during live military exercises.

  14. Evaluation of narrow transverse contraction joints in jointed plain concrete pavements.

    DOT National Transportation Integrated Search

    2006-03-01

    This report presents the results of a research project conducted at the Louisiana Transportation Research Center (LTRC) to evaluate the performance of narrow transverse contraction joints to control cracking in jointed plain concrete pavements. In ad...

  15. Announcing a Community Effort to Create an Information Model for Research Software Archives

    NASA Astrophysics Data System (ADS)

    Million, C.; Brazier, A.; King, T.; Hayes, A.

    2018-04-01

    An effort has started to create recommendations and standards for the archiving of planetary science research software. The primary goal is to define an information model that is consistent with OAIS standards.

  16. Dynamic Analyses Including Joints Of Truss Structures

    NASA Technical Reports Server (NTRS)

    Belvin, W. Keith

    1991-01-01

    Method for mathematically modeling joints to assess influences of joints on dynamic response of truss structures developed in study. Only structures with low-frequency oscillations considered; only Coulomb friction and viscous damping included in analysis. Focus of effort to obtain finite-element mathematical models of joints exhibiting load-vs.-deflection behavior similar to measured load-vs.-deflection behavior of real joints. Experiments performed to determine stiffness and damping nonlinearities typical of joint hardware. Algorithm for computing coefficients of analytical joint models based on test data developed to enable study of linear and nonlinear effects of joints on global structural response. Besides intended application to large space structures, applications in nonaerospace community include ground-based antennas and earthquake-resistant steel-framed buildings.

  17. A field evaluation of Transflex bridge joint performance.

    DOT National Transportation Integrated Search

    1972-01-01

    Presented are the results of a field evaluation of the various types of the General Tire Transflex joint known to be in use in Virginia. An effort was made, whenever possible, to qualitatively evaluate the joints with respect to their (1) watertightn...

  18. The joint center for energy storage research: A new paradigm for battery research and development

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Crabtree, George

    2015-03-30

    The Joint Center for Energy Storage Research (JCESR) seeks transformational change in transportation and the electricity grid driven by next generation high performance, low cost electricity storage. To pursue this transformative vision JCESR introduces a new paradigm for battery research: integrating discovery science, battery design, research prototyping and manufacturing collaboration in a single highly interactive organization. This new paradigm will accelerate the pace of discovery and innovation and reduce the time from conceptualization to commercialization. JCESR applies its new paradigm exclusively to beyond-lithium-ion batteries, a vast, rich and largely unexplored frontier. This review presents JCESR's motivation, vision, mission, intended outcomesmore » or legacies and first year accomplishments.« less

  19. DEVELOPMENT, INSTALLATION AND OPERATION OF THE MPC&A OPERATIONS MONITORING (MOM) SYSTEM AT THE JOINT INSTITUTE FOR NUCLEAR RESEARCH (JINR) DUBNA, RUSSIA

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kartashov,V.V.; Pratt,W.; Romanov, Y.A.

    The Material Protection, Control and Accounting (MPC&A) Operations Monitoring (MOM) systems handling at the International Intergovernmental Organization - Joint Institute for Nuclear Research (JINR) is described in this paper. Category I nuclear material (plutonium and uranium) is used in JINR research reactors, facilities and for scientific and research activities. A monitoring system (MOM) was installed at JINR in April 2003. The system design was based on a vulnerability analysis, which took into account the specifics of the Institute. The design and installation of the MOM system was a collaborative effort between JINR, Brookhaven National Laboratory (BNL) and the U.S. Departmentmore » of Energy (DOE). Financial support was provided by DOE through BNL. The installed MOM system provides facility management with additional assurance that operations involving nuclear material (NM) are correctly followed by the facility personnel. The MOM system also provides additional confidence that the MPC&A systems continue to perform effectively.« less

  20. Soils under fire: soils research and the Joint Fire Science Program.

    Treesearch

    Heather E. Erickson; Rachel White

    2008-01-01

    Soils are fundamental to a healthy and functioning ecosystem. Therefore, forest land managers can greatly benefit from a more thorough understanding of the ecological impacts of fire and fuel management activities on the vital services soils provide. We present a summary of new research on fire effects and soils made possible through the Joint Fire Science Program and...

  1. Load emphasizes muscle effort minimization during selection of arm movement direction

    PubMed Central

    2012-01-01

    Background Directional preferences during center-out horizontal shoulder-elbow movements were previously established for both the dominant and non-dominant arm with the use of a free-stroke drawing task that required random selection of movement directions. While the preferred directions were mirror-symmetrical in both arms, they were attributed to a tendency specific for the dominant arm to simplify control of interaction torque by actively accelerating one joint and producing largely passive motion at the other joint. No conclusive evidence has been obtained in support of muscle effort minimization as a contributing factor to the directional preferences. Here, we tested whether distal load changes directional preferences, making the influence of muscle effort minimization on the selection of movement direction more apparent. Methods The free-stroke drawing task was performed by the dominant and non-dominant arm with no load and with 0.454 kg load at the wrist. Motion of each arm was limited to rotation of the shoulder and elbow in the horizontal plane. Directional histograms of strokes produced by the fingertip were calculated to assess directional preferences in each arm and load condition. Possible causes for directional preferences were further investigated by studying optimization across directions of a number of cost functions. Results Preferences in both arms to move in the diagonal directions were revealed. The previously suggested tendency to actively accelerate one joint and produce passive motion at the other joint was supported in both arms and load conditions. However, the load increased the tendency to produce strokes in the transverse diagonal directions (perpendicular to the forearm orientation) in both arms. Increases in required muscle effort caused by the load suggested that the higher frequency of movements in the transverse directions represented increased influence of muscle effort minimization on the selection of movement direction. This

  2. [The development of research in tribology of artificial joints].

    PubMed

    Dai, Zhendong; Gong, Juanqing

    2006-06-01

    Aseptic loosening of the prosthesis is a major form for the failure of artificial joints, which results in the conglomeration of wear particles at the bone-implant interface. This paper briefly reviews the recent development of tribology of artificial joints preserving good lubrication, enhancing the wear resistance of materials for the joints, reducing the generation of sensitive-size particles and depressing the debris-tissue reactions. Suggestion for improvement in the design of artificial joints is presented.

  3. Structural analysis of a bolted joint concept for the space shuttle's solid rocket motor casing

    NASA Technical Reports Server (NTRS)

    Lindell, Michael C.; Stalnaker, Winifred A.

    1987-01-01

    The Space Shuttle Challenger accident is thought to have been caused by the failure of one of the tang-clevis joints joining together the casing segments of the Solid Rocket Motors (SRM). Excessive displacement between the tang and clevis, possibly unseating the O-ring seals, may have initiated the resulting accident. An effort was made at NASA Langley Research Center to design an alternative concept for mating the casing segments. A bolted flange joint concept was designed and analyzed to determine if the concept would effectively maintain a seal while minimizing joint weight and controlling stress levels. It is shown that under the loading conditions analyzed the seal area of the joint remains seated. The only potential stress problem is a stress concentration in the flange at the edge of the bolt hole, which is highly localized. While heavier than the existing joint, this concept does have some advantages making the bolted joint an attractive alternative.

  4. Joint Group on Pollution Prevention: Partnering for Progress

    NASA Technical Reports Server (NTRS)

    Hill, R.

    2001-01-01

    This viewgraph presentation outlines the Joint Group on Pollution Prevention (JG-PP) partnership. Details are given on what groups comprise JG-PP, the proven methodology for what JG-PP can accomplish, the common problems, joint solutions, and shared efforts, and some of the JG-PP projects.

  5. Proposal for research and education: joint lectures and practicals on central nervous system anatomy and physiology.

    PubMed

    Kageyama, Ikuo; Yoshimura, Ken; Satoh, Yoshihide; Nanayakkara, Chinthani D; Pallegama, Ranjith W; Iwasaki, Shin-Ichi

    2016-07-01

    We coordinated anatomy and physiology lectures and practicals to facilitate an integrated understanding of morphology and function in a basic medical science program for dental students and to reduce the time spent on basic science education. This method is a means to provide the essential information and skills in less time. The overall impression was that the practice of joint central nervous system lectures and practicals was an efficient method for students, which suggests that joint lectures might also be useful for clinical subjects. About two-thirds of students felt that the joint anatomy and physiology lecture on the central nervous system was useful and necessary in understanding the relationship between morphology and function, at least for this subject. One-third of students were neutral on the effectiveness of this method. However, the survey results suggest that improvements are needed in the method and timing of joint lectures and practicals. The present teaching approach can be further improved by conducting combined lectures in which the form and function of anatomic structures are presented by the relevant departments during the same lecture. Finally, joint lecturers and practicals offer an opportunity to increase student understanding of the importance of new research findings by the present authors and other researchers.

  6. Longitudinal joint treatment, interim report - third year, March 2004.

    DOT National Transportation Integrated Search

    2004-03-01

    Maine highways have been showing signs of longitudinal joint failure for a number of years. In an effort : to reduce the amount of joint failures the Maine Department of Transportation (MDOT) is currently : evaluating two projects. One project is mon...

  7. Longitudinal joint treatment, interim report - fourth year, March 2005.

    DOT National Transportation Integrated Search

    2005-03-01

    Maine highways have been showing signs of longitudinal joint failure for a number of years. In an effort : to reduce the amount of joint failures the Maine Department of Transportation (MDOT) is currently : evaluating two projects. One project is mon...

  8. Joint Improvised Explosive Device Defeat Organization Annual Report 2010

    DTIC Science & Technology

    2010-01-01

    Fox is an effort to characterize a COTS, man-portable, radiography system exceeding current EOD radiography penetration capabilities. Gray Fox... rocket propelled grenades at a reduced weight compared to currently available armor solutions. Sentinel Scout. This developmental appliqué kit is...Dismounted System Joint Electronic warfare Cour&e Joint Total Entity Tracking for the Instrumented Battlefield Joint Readinoss Training Contor

  9. Joint Program Management Handbook

    DTIC Science & Technology

    1994-12-01

    service networks , and unique requirements, such as in the special opeations area, require a special effort by joint program managers Figure 3-3...the Engieermg and Manufacuring Devopment Phase. Nfilestoae HI- Develommen Annros Devopment approval marks a significant step for any program, but it is

  10. Joint Research on Scatterometry and AFM Wafer Metrology

    NASA Astrophysics Data System (ADS)

    Bodermann, Bernd; Buhr, Egbert; Danzebrink, Hans-Ulrich; Bär, Markus; Scholze, Frank; Krumrey, Michael; Wurm, Matthias; Klapetek, Petr; Hansen, Poul-Erik; Korpelainen, Virpi; van Veghel, Marijn; Yacoot, Andrew; Siitonen, Samuli; El Gawhary, Omar; Burger, Sven; Saastamoinen, Toni

    2011-11-01

    Supported by the European Commission and EURAMET, a consortium of 10 participants from national metrology institutes, universities and companies has started a joint research project with the aim of overcoming current challenges in optical scatterometry for traceable linewidth metrology. Both experimental and modelling methods will be enhanced and different methods will be compared with each other and with specially adapted atomic force microscopy (AFM) and scanning electron microscopy (SEM) measurement systems in measurement comparisons. Additionally novel methods for sophisticated data analysis will be developed and investigated to reach significant reductions of the measurement uncertainties in critical dimension (CD) metrology. One final goal will be the realisation of a wafer based reference standard material for calibration of scatterometers.

  11. Summary of U.S. research on wood transportation structures

    Treesearch

    M. A. Ritter; R. C. Moody; S. R. Duwadi

    1996-01-01

    An extensive U.S. research program to further develop wood utilization in transportation structures is currently in progress as a joint effort of the USDA Forest Service, Forest Products Laboratory, and the U.S. Department of Transportation, Federal Highway Administration. This research is funded primarily by U.S. legislation and involves cooperative research with...

  12. Joint Control: A Discussion of Recent Research

    PubMed Central

    Palmer, David C

    2006-01-01

    The discrimination of the onset of joint control is an important interpretive tool in explaining matching behavior and other complex phenomena, but the difficulty of getting experimental control of all relevant variables stands in the way of a definitive experiment. The studies in the present issue of The Analysis of Verbal Behavior illustrate how modest experiments can take their place in a web of interpretation to make a strong case that joint control is a necessary element of such phenomena. PMID:22477357

  13. Joint Force Cyberspace Component Command: Establishing Cyberspace Operations Unity of Effort for the Joint Force Commander

    DTIC Science & Technology

    2015-05-01

    say/. According to the article, “the hackers targeted big-name makers of nuclear and solar technology, stealing confidential business information...As JTF-GNO synchronized efforts to disinfect and protect over 2.5 million computers in 3,500 DoD organizations spanning 99 countries, Defense

  14. Passion Research: A Joint Venture To Interest High School Students in Chemistry.

    ERIC Educational Resources Information Center

    Carriere, Francois J.; Abouaf, Madeleine

    1997-01-01

    Describes a joint venture between the Centre National de la Recherche Scientifique (CNRS) and the Department of Education in France that was created to allow students to do practical scientific work with the help of a CNRS researcher. Presents two practical projects done by students on organic polymers and on color. Concludes that this increases…

  15. Joint Detect and Avoid Flight Testing

    NASA Technical Reports Server (NTRS)

    Maliska, Heather; Estrada, Ramon; Euteneuer, Eric; Gong, Chester; Arthur, Keith

    2015-01-01

    This presentation gives insight into a joint flight testing effort that included participation from NASA, Honeywell, and General Atomics. The presentation includes roles and responsibilities, test flow, and encounter requirements and summary.

  16. Whatever Happened to Joint Vision 2010

    DTIC Science & Technology

    2010-04-02

    submitted to the Faculty of the Joint Advanced Warfighting School in partial satisfaction of the requirements of a Master of Science Degree in Joint...Service efforts and evolve “jointness” beyond the dictates of the 1986 Goldwater-Nichols Act. JV2010 delineated a common set of environmental ...towards something that is fresh, new and important. In this sense, the term vision may have been the wrong term. Warren Bennis and Burt Nanus, noted

  17. Harmonization in preclinical epilepsy research: A joint AES/ILAE translational initiative.

    PubMed

    Galanopoulou, Aristea S; French, Jacqueline A; O'Brien, Terence; Simonato, Michele

    2017-11-01

    Among the priority next steps outlined during the first translational epilepsy research workshop in London, United Kingdom (2012), jointly organized by the American Epilepsy Society (AES) and the International League Against Epilepsy (ILAE), are the harmonization of research practices used in preclinical studies and the development of infrastructure that facilitates multicenter preclinical studies. The AES/ILAE Translational Task Force of the ILAE has been pursuing initiatives that advance these goals. In this supplement, we present the first reports of the working groups of the Task Force that aim to improve practices of performing rodent video-electroencephalography (vEEG) studies in experimental controls, generate systematic reviews of preclinical research data, and develop preclinical common data elements (CDEs) for epilepsy research in animals. Wiley Periodicals, Inc. © 2017 International League Against Epilepsy.

  18. Computer Assisted Surgery and Current Trends in Orthopaedics Research and Total Joint Replacements

    NASA Astrophysics Data System (ADS)

    Amirouche, Farid

    2008-06-01

    Musculoskeletal research has brought about revolutionary changes in our ability to perform high precision surgery in joint replacement procedures. Recent advances in computer assisted surgery as well better materials have lead to reduced wear and greatly enhanced the quality of life of patients. The new surgical techniques to reduce the size of the incision and damage to underlying structures have been the primary advance toward this goal. These new techniques are known as MIS or Minimally Invasive Surgery. Total hip and knee Arthoplasties are at all time high reaching 1.2 million surgeries per year in the USA. Primary joint failures are usually due to osteoarthristis, rheumatoid arthritis, osteocronis and other inflammatory arthritis conditions. The methods for THR and TKA are critical to initial stability and longevity of the prostheses. This research aims at understanding the fundamental mechanics of the joint Arthoplasty and providing an insight into current challenges in patient specific fitting, fixing, and stability. Both experimental and analytical work will be presented. We will examine Cementless total hip arthroplasty success in the last 10 years and how computer assisted navigation is playing in the follow up studies. Cementless total hip arthroplasty attains permanent fixation by the ingrowth of bone into a porous coated surface. Loosening of an ingrown total hip arthroplasty occurs as a result of osteolysis of the periprosthetic bone and degradation of the bone prosthetic interface. The osteolytic process occurs as a result of polyethylene wear particles produced by the metal polyethylene articulation of the prosthesis. The total hip arthroplasty is a congruent joint and the submicron wear particles produced are phagocytized by macrophages initiating an inflammatory cascade. This cascade produces cytokines ultimately implicated in osteolysis. Resulting bone loss both on the acetabular and femoral sides eventually leads to component instability. As

  19. Innovative remote monitoring of plant health for environmental applications: A joint effort between EPCOT{reg_sign} and the DOE

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Robitaille, H.; Capelle, G.; Di Benedetto, J.

    1996-12-31

    In September of 1994, the US Department of Energy (DOE), Environmental Management, Office of Science and Technology for (OST) and Epcot{reg_sign} in the WALT DISNEY WORLD{reg_sign} Resort (Epcot) signed an agreement to cooperate on the research, development, and public communication and display of environmental technologies. Although Epcot and OST have distinctive missions, certain areas of their respective research and development efforts are common, including the integration of remote sensors with robotics platforms, airborne surveys for environmental characterization and monitoring, and ground based measurements of vegetation stress. The first area of cooperative R&D pursued under the agreement is the evaluation ofmore » laser-induced fluorescence imaging (LIFI), a technology developed by OST and proven effective for uranium detection. This paper describes the efforts being conducted under the Epcot-OST agreement and presents initial results. An appendix describing LIFI technology is also included.« less

  20. Wormhole Formation in RSRM Nozzle Joint Backfill

    NASA Technical Reports Server (NTRS)

    Stevens, J.

    2000-01-01

    The RSRM nozzle uses a barrier of RTV rubber upstream of the nozzle O-ring seals. Post flight inspection of the RSRM nozzle continues to reveal occurrence of "wormholes" into the RTV backfill. The term "wormholes", sometimes called "gas paths", indicates a gas flow path not caused by pre-existing voids, but by a little-understood internal failure mode of the material during motor operation. Fundamental understanding of the mechanics of the RSRM nozzle joints during motor operation, nonlinear viscoelastic characterization of the RTV backfill material, identification of the conditions that predispose the RTV to form wormholes, and screening of candidate replacement materials is being pursued by a joint effort between Thiokol Propulsion, NASA, and the Army Propulsion & Structures Directorate at Redstone Arsenal. The performance of the RTV backfill in the joint is controlled by the joint environment. Joint movement, which applies a tension and shear load on the material, coupled with the introduction of high pressure gas in combination create an environment that exceeds the capability of the material to withstand the wormhole effect. Little data exists to evaluate why the material fails under the modeled joint conditions, so an effort to characterize and evaluate the material under these conditions was undertaken. Viscoelastic property data from characterization testing will anchor structural analysis models. Data over a range of temperatures, environmental pressures, and strain rates was used to develop a nonlinear viscoelastic model to predict material performance, develop criteria for replacement materials, and quantify material properties influencing wormhole growth. Three joint simulation analogs were developed to analyze and validate joint thermal barrier (backfill) material performance. Two exploratory tests focus on detection of wormhole failure under specific motor operating conditions. A "validation" test system provides data to "validate" computer models and

  1. Influence of running velocity on vertical, leg and joint stiffness : modelling and recommendations for future research.

    PubMed

    Brughelli, Matt; Cronin, John

    2008-01-01

    Human running can be modelled as either a spring-mass model or multiple springs in series. A force is required to stretch or compress the spring, and thus stiffness, the variable of interest in this paper, can be calculated from the ratio of this force to the change in spring length. Given the link between force and length change, muscle stiffness and mechanical stiffness have been areas of interest to researchers, clinicians, and strength and conditioning practitioners for many years. This review focuses on mechanical stiffness, and in particular, vertical, leg and joint stiffness, since these are the only stiffness types that have been directly calculated during human running. It has been established that as running velocity increases from slow-to-moderate values, leg stiffness remains constant while both vertical stiffness and joint stiffness increase. However, no studies have calculated vertical, leg or joint stiffness over a range of slow-to-moderate values to maximum values in an athletic population. Therefore, the effects of faster running velocities on stiffness are relatively unexplored. Furthermore, no experimental research has examined the effects of training on vertical, leg or joint stiffness and the subsequent effects on running performance. Various methods of training (Olympic style weightlifting, heavy resistance training, plyometrics, eccentric strength training) have shown to be effective at improving running performance. However, the effects of these training methods on vertical, leg and joint stiffness are unknown. As a result, the true importance of stiffness to running performance remains unexplored, and the best practice for changing stiffness to optimize running performance is speculative at best. It is our hope that a better understanding of stiffness, and the influence of running speed on stiffness, will lead to greater interest and an increase in experimental research in this area.

  2. 78 FR 20120 - Cooperative Research and Development Agreement: Joint Technical Demonstration of Tactical Data...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-03

    ... Development Agreement: Joint Technical Demonstration of Tactical Data Link Range Enhancement Software AGENCY... (TDL) range enhancement software technologies to improve operational effectiveness and communications... Range Enhancement Software Technologies, U.S. Coast Guard Research and Development Center, 1 Chelsea...

  3. Evaluating U.S. medical schools' efforts to educate faculty researchers on research integrity and research misconduct policies and procedures.

    PubMed

    Titus, Sandra Larsen

    2014-01-01

    This paper examines how well U.S. medical school institutions are doing to promote research integrity. It is an important question to ask in order to determine whether there are sufficient and adequate protections in place to protect the U.S. Public Health Service's (PHS) resources devoted to medical research. This paper focuses on 5,100 medical school researchers' knowledge of what constitutes research misconduct as well as their willingness to report it to the research integrity officer (RIO) and educate their Ph.D. trainees. We learned that 5.6% of researchers could correctly distinguish seven or more of the nine scenarios that depicted likely research misconduct, as defined by the PHS regulations, from scenarios describing other ethical issues. Instead, researchers had expansive definitions and often inappropriately identified infractions such as conflicts of interest, Institutional Review Board (IRB) violations, and other breaches in ethical standards to be research misconduct. In addition, researchers who correctly identified four instances of likely research misconduct in the test items were highly unlikely to report their observations to a RIO. Researchers also provided insight on the factors they believe influence their decision making process of whether to report research misconduct. In addition, this paper also reports on the guidance that faculty said they provided their trainees on research misconduct issues. We conclude with a discussion and recommendations on what institutional leaders might consider doing in order to enhance their research integrity efforts and protect their institution's reputation.

  4. Fisher research in the US Rocky Mountains: A critical overview

    Treesearch

    Michael Schwartz; J. Sauder

    2013-01-01

    In this talk we review the recent fisher research and monitoring efforts that have occurred throughout Idaho and Montana in past 2 decades. We begin this talk with a summary of the habitat relationship work that has examined fisher habitat use at multiple scales. These have largely been conducted using radio and satellite telemetry, although a new, joint effort to use...

  5. The research of laryngeal joints to reconstruction and modeling.

    PubMed

    Zhang, Yi; Shi, Tingchun

    2014-01-01

    Larynx has a complex structure with joints and multiple functions. In order to study the artificial larynx and artificial auricle scaffold, a three-dimensional digital model of laryngeal joint is established in this paper using MIMICS with its biomechanical properties analyzed and calculated by using the finite element method. This model is based on the CT scanned images of 281 layers with an interlamellar spacing of 1.25 mm. The obtained data are denoised, segmented and smoothed before being loaded into MIMICS. By further optimizations, an accurate and complete 3D model can be obtained. Subsequently, a 3D FEM of the normal larynx joint is performed which allows observations from any dimensions and angles. Compared with natural laryngeal joint, this model has good geometric similarity and mechanically similar throat voicing functions.

  6. The selection of the American-Polish joint venture projects for the Krakow program and results of the efforts to date

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gyorke, D.F.; Butcher, T.A.

    1995-12-31

    To implement the Krakow Clean Fossil Fuels and Energy Efficiency Program, eight U.S. firms were selected by the U.S. Department of Energy to market their technologies to reduce pollution from low emission sources in Krakow. The eight U.S. firms were selected by a competitive solicitation that required the proposing firms to themselves provide funding to match or exceed the funding provided by the Program. These U.S. firms and their Polish partner companies have begun sales and cooperative work efforts in Krakow, and some have already made initial equipment installations with measurable performance improvements. Following their efforts as part of themore » Program, these U.S.-Polish joint ventures will market their technologies and achieve the associated environmental benefits elsewhere in Poland and Eastern and Central Europe. As part of the Krakow Program a spreadsheet model was developed to compare technological options for supplying heat to the city by calculation and comparing the heating costs and associated emissions reduction for each option. Comparison of options is made on the basis of the user cost-per-metric ton of equivalent emissions reduction. For all options considered in the Krakow Program, this cost parameter has ranged from -$1469 (best) to $2650 (worst). The costs for technologies associated with the eight projects in the Krakow Program are at the lower end of this range placing these technologies among the most cost effective solutions to the pollution problems from the low emission sources.« less

  7. A Successful Experiment in Collaboration: U.S. Science Agencies Forge Major Joint IPY Outreach Efforts

    NASA Astrophysics Data System (ADS)

    Cole, S.; Goldman, J.; West, P.

    2008-12-01

    The International Polar Year (IPY) provided U.S. agencies involved in polar research with a major outreach challenge: how to portray a unified view of the wealth of federal activity through a communications network dominated by agency-focused channels. To meet this challenge, 16 federal agencies joined together in an ongoing interagency working group, lead by the National Science Foundation's Office of Polar Programs, resulting in a series of successful media and public outreach endeavors. These included a unique interagency U.S. IPY web site (www.ipy.gov) that allowed participating agencies to independently upload relevant information every day; a major IPY kickoff event at the National Academies of Science; and a joint NASA/NSF/USGS televised press conference unveiling a new satellite map of Antarctica. Key to these successes was the interagency working group, which facilitated in-depth and sustained interaction between the agencies in coordinating development of outreach strategies both at the agency and federal level.

  8. THE NATIONAL ENVIRONMENTAL SPECIMEN BANK RESEARCH PROGRAM FOR SAMPLING, STORAGE, AND ANALYSIS

    EPA Science Inventory

    The work was performed under a joint NBS/EPA research program to develop state-of-the-art protocols for sampling, storage, and analysis of biological and environmental-type matrices. This report is a compliation of research papers and/or efforts describing developed or adopted pr...

  9. Advancing Globally Integrated Logistics Effort 2017 Wargame Report

    DTIC Science & Technology

    2017-09-01

    September 2017 Dr. M. Webster Ewell, Jr. Director, Integration and Gaming Team Advanced Technology and Systems Analysis REPORT...release: distribution unlimited. 13. SUPPLEMENTARY NOTES 14. ABSTRACT This report describes the execution and analysis of a logistics game created for...the Joint Staff J-4, Directorate for Logistics. The game , Advancing Globally Integrated Logistics Effort 2017 (AGILE 17), centered on developing a

  10. The Joint Institute for Nuclear Research in Experimental Physics of Elementary Particles

    NASA Astrophysics Data System (ADS)

    Bednyakov, V. A.; Russakovich, N. A.

    2018-05-01

    The year 2016 marks the 60th anniversary of the Joint Institute for Nuclear Research (JINR) in Dubna, an international intergovernmental organization for basic research in the fields of elementary particles, atomic nuclei, and condensed matter. Highly productive advances over this long road clearly show that the international basis and diversity of research guarantees successful development (and maintenance) of fundamental science. This is especially important for experimental research. In this review, the most significant achievements are briefly described with an attempt to look into the future (seven to ten years ahead) and show the role of JINR in solution of highly important problems in elementary particle physics, which is a fundamental field of modern natural sciences. This glimpse of the future is full of justified optimism.

  11. Predicting the Functional Roles of Knee Joint Muscles from Internal Joint Moments.

    PubMed

    Flaxman, Teresa E; Alkjær, Tine; Simonsen, Erik B; Krogsgaard, Michael R; Benoit, Daniel L

    2017-03-01

    Knee muscles are commonly labeled as flexors or extensors and aptly stabilize the knee against sagittal plane loads. However, how these muscles stabilize the knee against adduction-abduction and rotational loads remains unclear. Our study sought 1) to classify muscle roles as they relate to joint stability by quantifying the relationship between individual muscle activation patterns and internal net joint moments in all three loading planes and 2) to determine whether these roles change with increasing force levels. A standing isometric force matching protocol required subjects to modulate ground reaction forces to elicit various combinations and magnitudes of sagittal, frontal, and transverse internal joint moments. Surface EMG measured activities of 10 lower limb muscles. Partial least squares regressions determined which internal moment(s) were significantly related to the activation of individual muscles. Rectus femoris and tensor fasciae latae were classified as moment actuators for knee extension and hip flexion. Hamstrings were classified as moment actuators for hip extension and knee flexion. Gastrocnemius and hamstring muscles were classified as specific joint stabilizers for knee rotation. Vastii were classified as general joint stabilizers because activation was independent of moment generation. Muscle roles did not change with increasing effort levels. Our findings indicate muscle activation is not dependent on anatomical orientation but perhaps on its role in maintaining knee joint stability in the frontal and transverse loading planes. This is useful for delineating the roles of biarticular knee joint muscles and could have implications in robotics, musculoskeletal modeling, sports sciences, and rehabilitation.

  12. Cognitive effort: A neuroeconomic approach

    PubMed Central

    Braver, Todd S.

    2015-01-01

    Cognitive effort has been implicated in numerous theories regarding normal and aberrant behavior and the physiological response to engagement with demanding tasks. Yet, despite broad interest, no unifying, operational definition of cognitive effort itself has been proposed. Here, we argue that the most intuitive and epistemologically valuable treatment is in terms of effort-based decision-making, and advocate a neuroeconomics-focused research strategy. We first outline psychological and neuroscientific theories of cognitive effort. Then we describe the benefits of a neuroeconomic research strategy, highlighting how it affords greater inferential traction than do traditional markers of cognitive effort, including self-reports and physiologic markers of autonomic arousal. Finally, we sketch a future series of studies that can leverage the full potential of the neuroeconomic approach toward understanding the cognitive and neural mechanisms that give rise to phenomenal, subjective cognitive effort. PMID:25673005

  13. Climate Change Modeling Needs and Efforts for Hydroelectric System Operations in the Pacific Northwest

    NASA Astrophysics Data System (ADS)

    Pytlak, E.

    2014-12-01

    This presentation will outline ongoing, multi-year hydroclimate change research between the Columbia River Management Joint Operating Committee (RMJOC), The University of Washington, Portland State University, and their many regional research partners and stakeholders. Climate change in the Columbia River Basin is of particular concern to the Bonneville Power Administration (BPA) and many Federal, Tribal and regional stakeholders. BPA, the U.S. Army Corp of Engineers, and U.S. Bureau of Reclamation, which comprise the RMJOC, conducted an extensive study in 2009-11 using climate change streamflows produced by the University of Washington Climate Impacts Group (CIG). The study reconfirmed that as more winter precipitation in the Columbia Basin falls as rain rather than snow by mid-century, particularly on the U.S. portion of the basin, increased winter runoff is likely, followed by an earlier spring snowmelt peak, followed by less summer flows as seasonal snowmelt diminished earlier in the water year. Since that initial effort, both global and regional climate change modeling has advanced. To take advantage of the new outputs from the Fifth Coupled Model Intercomparison Project (CMIP-5), the RMJOC, through BPA support, is sponsoring new hydroclimate research which considers not only the most recent information from the GCMs, but also the uncertainties introduced by the hydroclimate modeling process itself. Historical streamflows, which are used to calibrate hydrologic models and ascertain their reliability, are subject to both measurement and modeling uncertainties. Downscaling GCMs to a hydrologically useful spatial and temporal resolution introduces uncertainty, depending on the downscaling methods. Hydrologic modeling introduces uncertainties from calibration and geophysical states, some of which, like land surface characteristics, are likely to also change with time. In the upper Columbia Basin, glacier processes introduce yet another source of uncertainty. The

  14. Breaking the Biological Barriers to Cellulosic Ethanol: A Joint Research Agenda

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Houghton, John; Weatherwax, Sharlene; Ferrell, John

    2006-06-07

    The Biomass to Biofuels Workshop, held December 7–9, 2005, was convened by the Department of Energy’s Office of Biological and Environmental Research in the Office of Science; and the Office of the Biomass Program in the Office of Energy Efficiency and Renewable Energy. The purpose was to define barriers and challenges to a rapid expansion of cellulosic-ethanol production and determine ways to speed solutions through concerted application of modern biology tools as part of a joint research agenda. Although the focus was ethanol, the science applies to additional fuels that include biodiesel and other bioproducts or coproducts having critical rolesmore » in any deployment scheme.« less

  15. Design and technical support for development of a molded fabric space suit joint

    NASA Technical Reports Server (NTRS)

    Olson, L. Howard

    1994-01-01

    NASA Ames Research Center has under design a new joint or element for use in a space suit. The design concept involves molding a fabric to a geometry developed at Ames. Unusual characteristics of this design include the need to produce a fabric molding draw ratio on the order of thirty percent circumferentially on the surface. Previous work done at NASA on molded fabric joints has shown that standard, NASA qualified polyester fabrics as are currently available in the textile industry for use in suits have a maximum of about fifteen percent draw ratio. NASA has done the fundamental design for a prototype joint and of a mold which would impart the correct shape to the fabric support layer of the joint. NASA also has the capability to test a finished product for suitability and reliability. Responsibilities resting with Georgia Tech in the design effort for this project are textile related, namely fiber selection, fabric design to achieve the properties of the objective design, and determining production means and sources for the fabrics. The project goals are to produce a prototype joint using the NASA design for evaluation of effectiveness by NASA, and to establish the sources and specifications which would allow reliable and repeatable production of the joint.

  16. Teaching Engineering Ethics to PhD Students: A Berkeley-Delft Initiative : Commentary on "Ethics Across the Curriculum: Prospects for Broader (and Deeper) Teaching and Learning in Research and Engineering Ethics".

    PubMed

    Taebi, Behnam; Kastenberg, William E

    2016-07-13

    A joint effort by the University of California at Berkeley and Delft University of Technology to develop a graduate engineering ethics course for PhD students encountered two types of challenges: academic and institutional. Academically, long-term collaborative research efforts between engineering and philosophy faculty members might be needed before successful engineering ethics courses can be initiated; the teaching of ethics to engineering graduate students and collaborative research need to go hand-in-hand. Institutionally, both bottom-up approaches at the level of the faculty and as a joint research and teaching effort, and top-down approaches that include recognition by a University's administration and the top level of education management, are needed for successful and sustainable efforts to teach engineering ethics.

  17. Nano Enabled Thermo-Mechanical Materials in Adhesive Joints: A New Paradigm to Materials Functionality (Preprint)

    DTIC Science & Technology

    2006-12-01

    interface as well as to minimize the interface contact resistance. There is an on- going effort by numerous researchers of dispersing conductive nano...constituents (single wall carbon nanotube (SWCNT), multi wall carbon nano tube ( MWCNT )) in polymers (adhesive) to enhance its thermal conductivity [1...propose to use vertically aligned MWCNT in joints to enhance through-thickness conductivity [10] because of its known high thermal conductivity

  18. Early Osteoarthritis of the Trapeziometacarpal Joint Is Not Associated With Joint Instability during Typical Isometric Loading

    PubMed Central

    Halilaj, Eni; Moore, Douglas C.; Patel, Tarpit K.; Ladd, Amy L.; Weiss, Arnold-Peter C.; Crisco, Joseph J.

    2015-01-01

    The saddle-shaped trapeziometacarpal (TMC) joint contributes importantly to the function of the human thumb. A balance between mobility and stability is essential in this joint, which experiences high loads and is prone to osteoarthritis (OA). Since instability is considered a risk factor for TMC OA, we assessed TMC joint instability during the execution of three isometric functional tasks (key pinch, jar grasp, and jar twist) in 76 patients with early TMC OA and 44 asymptomatic controls. Computed tomography images were acquired while subjects held their hands relaxed and while they applied 80% of their maximum effort for each task. Six degree-of-freedom rigid body kinematics of the metacarpal with respect to the trapezium from the unloaded to the loaded task positions were computed in terms of a TMC joint coordinate system. Joint instability was expressed as a function of the metacarpal translation and the applied force. We found that the TMC joint was more unstable during a key pinch task than during a jar grasp or a jar twist task. Sex, age, and early OA did not have an effect on TMC joint instability, suggesting that instability during these three tasks is not a predisposing factor in TMC OA. PMID:25941135

  19. Regionally Applied Research Efforts (RARE) Report titled " ...

    EPA Pesticide Factsheets

    The traditional methodology for health risk assessment used by the U. S. Environmental Protection Agency (EPA) is based on the use of exposure assumptions (e.g. exposure duration, food ingestion rate, body weight, etc.) that represent the entire American population, either as a central tendency exposure (e.g. average, median) or as a reasonable maximum exposure (e.g. 95% upper confidence limit). Unfortunately, EPA lacked exposure information for assessing health risks for New England regional tribes sustaining a tribal subsistence way of life. As a riverine tribe, the Penobscot culture and traditions are inextricably tied to the Penobscot River watershed. It is through hunting, fishing, trapping, gathering and making baskets, pottery, moccasins, birch-bark canoes and other traditional practices that the Penobscot culture and people are sustained. The Penobscot River receives a variety of pollutant discharges leaving the Penobscot Indian Nation (PIN) questioning the ecological health and water quality of the river and how this may affect the practices that sustain their way of life. The objectives of this Regional Applied Research Effort (RARE) study were to: (1) Develop culturally sensitive methodologies for assessing the potential level of exposure to contaminants that Penobscot Indian Nation tribal members may have from maintaining tribal sustenance practices; (2) Conduct field surveys and laboratory analysis on targeted flora and fauna for chemical expo

  20. Collaboration in Arctic Research: Best Practices to Build and Sustain Successful Cross- and Trans-disciplinary Efforts

    NASA Astrophysics Data System (ADS)

    Wiggins, H. V.; Rich, R. H.

    2015-12-01

    The rapid physical and social changes currently underway in the Arctic - and changes in the way in which we study and manage the region -- require coordinated research efforts to improve our understanding of the Arctic's physical, biological, and social systems and the implications of change at many scales. At the same time, policy-makers and Arctic communities need decision-support tools and synthesized information to respond and adapt to the "new Arctic". There are enormous challenges, however, in collaboration among the disparate groups of people needed for such efforts. A carefully planned strategic approach is required to bridge the scientific disciplinary and organizational boundaries, foster cooperation between local communities and science programs, and effectively communicate between scientists and policy-makers. Efforts must draw on bodies of knowledge from project management, strategic planning, organizational development, and group dynamics. This poster presentation will discuss best practices of building and sustaining networks of people to catalyze successful cross-disciplinary activities. Specific examples and case studies - both successes and failures -- will be presented that draw on several projects at the Arctic Research Consortium of the U.S. (ARCUS; www.arcus.org), a nonprofit membership organization composed of universities and institutions that have a substantial commitment to research in the Arctic.

  1. Best Practices of Collaboration in Arctic Research: How to Succeed, or Fail, in Cross-Disciplinary Efforts

    NASA Astrophysics Data System (ADS)

    Wiggins, H. V.

    2014-12-01

    The rapid physical and social changes currently underway in the Arctic - and changes in the way in which we study and manage the region - require coordinated research efforts to improve our understanding of the Arctic's physical, biological, and social systems. At the same time, policy-makers and Arctic communities need decision-support tools and synthesized information to respond and adapt to the "new arctic". There are enormous challenges, however, in collaboration among the disparate groups of people needed for such efforts. A carefully planned strategic approach is required to bridge the scientific disciplinary and organizational boundaries, foster cooperation between local communities and science programs, and effectively communicate between scientists and policy-makers. Efforts must draw on bodies of knowledge from project management, strategic planning, organizational development, group dynamics, and other fields. In addition, collaborations between scientific disciplines face challenges unique to scientific culture. This poster presentation will discuss best practices of building and sustaining networks of people to catalyze successful cross-disciplinary activities. Specific examples and case studies - both successes and failures - will be presented that draw on several projects at the Arctic Research Consortium of the U.S. (ARCUS; www.arcus.org), a nonprofit membership organization composed of universities and institutions that have a substantial commitment to research in the Arctic.

  2. Envri Cluster - a Community-Driven Platform of European Environmental Researcher Infrastructures for Providing Common E-Solutions for Earth Science

    NASA Astrophysics Data System (ADS)

    Asmi, A.; Sorvari, S.; Kutsch, W. L.; Laj, P.

    2017-12-01

    European long-term environmental research infrastructures (often referred as ESFRI RIs) are the core facilities for providing services for scientists in their quest for understanding and predicting the complex Earth system and its functioning that requires long-term efforts to identify environmental changes (trends, thresholds and resilience, interactions and feedbacks). Many of the research infrastructures originally have been developed to respond to the needs of their specific research communities, however, it is clear that strong collaboration among research infrastructures is needed to serve the trans-boundary research requires exploring scientific questions at the intersection of different scientific fields, conducting joint research projects and developing concepts, devices, and methods that can be used to integrate knowledge. European Environmental research infrastructures have already been successfully worked together for many years and have established a cluster - ENVRI cluster - for their collaborative work. ENVRI cluster act as a collaborative platform where the RIs can jointly agree on the common solutions for their operations, draft strategies and policies and share best practices and knowledge. Supporting project for the ENVRI cluster, ENVRIplus project, brings together 21 European research infrastructures and infrastructure networks to work on joint technical solutions, data interoperability, access management, training, strategies and dissemination efforts. ENVRI cluster act as one stop shop for multidisciplinary RI users, other collaborative initiatives, projects and programmes and coordinates and implement jointly agreed RI strategies.

  3. Lesson Co-Planning: Joint Efforts, Shared Success

    ERIC Educational Resources Information Center

    Carreño, Laura; Hernandez Ortiz, Luz Stella

    2017-01-01

    The present article reports the results of a qualitative research study conducted at a higher education institution in Bogotá Colombia. The study aimed at examining the lesson planning practices conducted by English language teachers at the proficiency program of the institution. The participants were a mix of the mentors in charge of each level…

  4. The Research and Training Activities for the Joint Institute for Aeronautics and Acoustics

    NASA Technical Reports Server (NTRS)

    Cantwell, Brian

    1997-01-01

    This proposal requests continued support for the program of activities to be undertaken by the Ames-Stanford Joint Institute for Aeronautics and Acoustics during the one-year period October 1, 1997 to September 30, 1998. The emphasis in this program is on training and research in experimental and computational methods with application to aerodynamics, acoustics and the important interactions between them. The program comprises activities in active flow control, Large Eddy Simulation of jet noise, flap aerodynamics and acoustics, high lift modeling studies and luminescent paint applications. During the proposed period there will be a continued emphasis on the interaction between NASA Ames, Stanford University and Industry, particularly in connection with the noise and high lift activities. The program will be conducted within the general framework of the Memorandum of Understanding (1976) establishing the Institute, as updated in 1993. As outlined in the agreement, the purposes of the Institute include the following: (1) To conduct basic and applied research; (2) to promote joint endeavors between Center scientists and those in the academic community; (3) to provide training to graduate students in specialized areas of aeronautics and acoustics through participation in the research programs of the Institute; (4) to provide opportunities for Post-Doctoral Fellows to collaborate in research programs of the Institute; and (5) to disseminate information about important aeronautical topics and to enable scientists and engineers of the Center to stay abreast of new advances through symposia, seminars and publications.

  5. The Research and Training Activities for the Joint Institute for Aeronautics and Acoustics

    NASA Technical Reports Server (NTRS)

    Cantwell, Brian

    1996-01-01

    This proposal requests continued support for the program of activities to be undertaken by the Ames-Stanford Joint Institute for Aeronautics and Acoustics during the one-year period October 1, 1996 to September 30, 1997. The emphasis in this program is on training and research in experimental and computational methods with application to aerodynamics, acoustics and the important interactions between them. The program comprises activities in active flow control, Large Eddy Simulation of jet noise, flap aerodynamics and acoustics, high lift modeling studies and luminescent paint applications. During the proposed period there will be a continued emphasis on the interaction between NASA Ames, Stanford University and Industry, particularly in connection with the noise and high lift activities. The program will be conducted within the general framework of the Memorandum of Understanding (1976) establishing the Institute, as updated in 1993. As outlined in the agreement, the purposes of the institute include the following: To conduct basic and applied research. To promote joint endeavors between Center scientists and those in the academic community To provide training to graduate students in specialized areas of aeronautics and acoustics through participation in the research programs of the Institute. To provide opportunities for Post-Doctoral Fellows to collaborate in research programs of the Institute. To disseminate information about important aeronautical topics and to enable scientists and engineers of the Center to stay abreast of new advances through symposia, seminars and publications.

  6. Dopamine, Effort-Based Choice, and Behavioral Economics: Basic and Translational Research

    PubMed Central

    Salamone, John D.; Correa, Merce; Yang, Jen-Hau; Rotolo, Renee; Presby, Rose

    2018-01-01

    Operant behavior is not only regulated by factors related to the quality or quantity of reinforcement, but also by the work requirements inherent in performing instrumental actions. Moreover, organisms often make effort-related decisions involving economic choices such as cost/benefit analyses. Effort-based decision making is studied using behavioral procedures that offer choices between high-effort options leading to relatively preferred reinforcers vs. low effort/low reward choices. Several neural systems, including the mesolimbic dopamine (DA) system and other brain circuits, are involved in regulating effort-related aspects of motivation. Considerable evidence indicates that mesolimbic DA transmission exerts a bi-directional control over exertion of effort on instrumental behavior tasks. Interference with DA transmission produces a low-effort bias in animals tested on effort-based choice tasks, while increasing DA transmission with drugs such as DA transport blockers tends to enhance selection of high-effort options. The results from these pharmacology studies are corroborated by the findings from recent articles using optogenetic, chemogenetic and physiological techniques. In addition to providing important information about the neural regulation of motivated behavior, effort-based choice tasks are useful for developing animal models of some of the motivational symptoms that are seen in people with various psychiatric and neurological disorders (e.g., depression, schizophrenia, Parkinson’s disease). Studies of effort-based decision making may ultimately contribute to the development of novel drug treatments for motivational dysfunction. PMID:29628879

  7. Dopamine, Effort-Based Choice, and Behavioral Economics: Basic and Translational Research.

    PubMed

    Salamone, John D; Correa, Merce; Yang, Jen-Hau; Rotolo, Renee; Presby, Rose

    2018-01-01

    Operant behavior is not only regulated by factors related to the quality or quantity of reinforcement, but also by the work requirements inherent in performing instrumental actions. Moreover, organisms often make effort-related decisions involving economic choices such as cost/benefit analyses. Effort-based decision making is studied using behavioral procedures that offer choices between high-effort options leading to relatively preferred reinforcers vs. low effort/low reward choices. Several neural systems, including the mesolimbic dopamine (DA) system and other brain circuits, are involved in regulating effort-related aspects of motivation. Considerable evidence indicates that mesolimbic DA transmission exerts a bi-directional control over exertion of effort on instrumental behavior tasks. Interference with DA transmission produces a low-effort bias in animals tested on effort-based choice tasks, while increasing DA transmission with drugs such as DA transport blockers tends to enhance selection of high-effort options. The results from these pharmacology studies are corroborated by the findings from recent articles using optogenetic, chemogenetic and physiological techniques. In addition to providing important information about the neural regulation of motivated behavior, effort-based choice tasks are useful for developing animal models of some of the motivational symptoms that are seen in people with various psychiatric and neurological disorders (e.g., depression, schizophrenia, Parkinson's disease). Studies of effort-based decision making may ultimately contribute to the development of novel drug treatments for motivational dysfunction.

  8. The joint cardiovascular research profile of the university medical centres in the Netherlands.

    PubMed

    van Welie, S D; van Leeuwen, T N; Bouma, C J; Klaassen, A B M

    2016-05-01

    Biomedical scientific research in the Netherlands has a good reputation worldwide. Quantitatively, the university medical centres (UMCs) deliver about 40 % of the total number of scientific publications of this research. Analysis of the bibliometric output data of the UMCs shows that their research is highly cited. These output-based analyses also indicate the high impact of cardiovascular scientific research in these centres, illustrating the strength of this research in the Netherlands. A set of six joint national cardiovascular research topics selected by the UMCs can be recognised. At the top are heart failure, rhythm disorder research and atherosclerosis. National collaboration of top scientists in consortia in these three areas is successful in acquiring funding of large-scale programs. Our observations suggest that funding national consortia of experts focused on a few selected research topics may increase the international competitiveness of cardiovascular research in the Netherlands.

  9. NASA Efforts on Nanotechnology

    NASA Technical Reports Server (NTRS)

    Miranda, Felix A.

    2003-01-01

    An overview of the field of nanotechnology within the theme of "New efforts in Nanotechnology Research," will be presented. NASA's interest, requirements and current efforts in this emerging field will be discussed. In particular, NASA efforts to develop nanoelectronic devices, fuel cells, and other applications of interest using this novel technology by collaborating with academia will be addressed. Progress on current collaborations in this area with the University of Puerto Rico will be highlighted.

  10. The Practice of Institutional Research. Proceedings of a Joint Conference of the Southern Association for Institutional Research and the North Carolina Association for Institutional Research (Charlotte, North Carolina, October 29-30, 1981).

    ERIC Educational Resources Information Center

    Martin, Mary P., Ed.; Staman, E. Michael, Ed.

    Proceedings of a 1981 joint conference sponsored by the Southern Association for Institutional Research (SAIR) and the North Carolina Association for Institutional Research are presented. The conference theme was the practice of institutional research. Contents include preconference workshop reports, speeches, abstracts of papers, and reports of…

  11. Research review: Social motivation and oxytocin in autism--implications for joint attention development and intervention.

    PubMed

    Stavropoulos, Katherine K M; Carver, Leslie J

    2013-06-01

    The social motivation hypothesis (SMH) suggests that individuals with autism spectrum disorders (ASD) are less intrinsically rewarded by social stimuli than their neurotypical peers. This difference in social motivation has been posited as a factor contributing to social deficits in ASD. Social motivation is thought to involve the neuropeptide oxytocin. Here, we review the evidence for oxytocin effects in ASD, and discuss its potential role in one important social cognitive behavior. Systematic searches were conducted using the PsychINFO and MEDLINE databases and the search terms 'oxytocin' and 'autism'; the same databases were used for separate searches for 'joint attention', 'intervention', and 'autism', using the same inclusion criteria as an earlier 2011 review but updating it for the period 2010 to October 2012. Several studies suggest that giving oxytocin to both individuals with ASD and neurotypical individuals can enhance performance on social cognitive tasks. Studies that have attempted to intervene in joint attention in ASD suggest that social motivation may be a particular obstacle to lasting effects. The review of the evidence for the SMH suggests a potential role for oxytocin in social motivation deficits in ASD. Because of its importance for later communicative and social development, the focus here is on implications of oxytocin and social motivation in the development of and interventions in joint attention. Joint attention is a central impairment in ASD, and as a result is the focus of several behavioral interventions. In describing this previous research on joint attention interventions in ASD, we pay particular attention to problems encountered in such studies, and propose ways that oxytocin may facilitate behavioral intervention in this area. For future research, integrating behavioral and pharmacological interventions (oxytocin administration) would be a worthwhile experimental direction to improve understanding of the role of oxytocin in ASD

  12. Would You Recommend Your Institution's Effort-Reporting Process to Others? Determining Best Practices in Effort-Reporting Compliance

    ERIC Educational Resources Information Center

    Whitaker, Ashley E.

    2015-01-01

    Effort-reporting compliance at higher education institutions was examined to discern best practices from those that would recommend their effort-reporting process. Data were derived from a survey of effort administrators--the research administrators responsible for the effort-reporting compliance program at their respective higher education…

  13. Status of DOE efforts to renew acceptance of foreign research reactor spent nuclear fuel

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Head, C.R.

    1997-08-01

    This presentation summarizes the efforts being made by the Department of Energy to renew acceptance of spent nuclear fuel shipments from foreign research reactors. The author reviews the actions undertaken in this process in a fairly chronological manner, through the present time, as well as the development of an environmental impact statement to support the proposed actions.

  14. Guilt and Effortful Control: Two Mechanisms that Prevent Disruptive Developmental Trajectories

    PubMed Central

    Kochanska, Grazyna; Barry, Robin A.; Jimenez, Natasha B.; Hollatz, Amanda L.; Woodard, Jarilyn

    2009-01-01

    Children's guilt associated with transgressions and their capacity for effortful control are both powerful forces that inhibit disruptive conduct. We examined how guilt and effortful control, repeatedly observed from toddler to preschool age, jointly predict children's disruptive outcomes in two multi-method multi-trait longitudinal studies (N's 57 and 99). Disruptive outcomes were rated by mothers at 73 months (Study 1) and mothers, fathers, and teachers at 52 and 67 months (Study 2). In both studies, guilt moderated effects of effortful control: For highly guilt-prone children, variations in effortful control were unrelated to future disruptive outcomes, but for children who were less guilt prone, effortful control predicted such outcomes. Guilt may inhibit transgressions through an automatic response due to negative arousal triggered by memories of past wrongdoing, regardless of child capacity for deliberate inhibition. Effortful control that engages a deliberate restraint may offset risk for disruptive conduct conferred by low guilt. PMID:19634978

  15. Establishing a Research and Evaluation Capability for the Joint Medical Education and Training Campus.

    PubMed

    Kirby, Sheila Nataraj; Marsh, Julie A; Thie, Harry J

    2011-01-01

    In calling for the transformation of military medical education and training, the 2005 Base Realignment and Closure Commission recommended relocating basic and specialty enlisted medical training to a single site to take advantage of economies of scale and the opportunity for joint training. As a result, a joint medical education and training campus (METC) has been established at Fort Sam Houston, Texas. Two of METC's primary long-term goals are to become a high-performing learning organization and to seek accreditation as a community college. Such goals require a clear model of organizational improvement with well-defined metrics for measuring its performance and using research and evaluation to assess and improve that performance. Lessons learned from a review of practices at institutions with similar missions-such as community colleges, corporate universities, the UK's Defence Medical Education and Training Agency, and other federal agencies, such as the Veterans Health Administration-establish a clear need for an office of institutional research to help METC attain its organizational goals. They also provide useful recommendations regarding the METC office's structure, scope, and governance.

  16. Establishing a Research and Evaluation Capability for the Joint Medical Education and Training Campus

    PubMed Central

    Kirby, Sheila Nataraj; Marsh, Julie A.; Thie, Harry J.

    2011-01-01

    Abstract In calling for the transformation of military medical education and training, the 2005 Base Realignment and Closure Commission recommended relocating basic and specialty enlisted medical training to a single site to take advantage of economies of scale and the opportunity for joint training. As a result, a joint medical education and training campus (METC) has been established at Fort Sam Houston, Texas. Two of METC's primary long-term goals are to become a high-performing learning organization and to seek accreditation as a community college. Such goals require a clear model of organizational improvement with well-defined metrics for measuring its performance and using research and evaluation to assess and improve that performance. Lessons learned from a review of practices at institutions with similar missions—such as community colleges, corporate universities, the UK's Defence Medical Education and Training Agency, and other federal agencies, such as the Veterans Health Administration—establish a clear need for an office of institutional research to help METC attain its organizational goals. They also provide useful recommendations regarding the METC office's structure, scope, and governance. PMID:28083182

  17. To Wield Excalibur: Seeking Unity of Effort in Joint Information Operations

    DTIC Science & Technology

    2002-06-07

    University of Michigan. In 1994, they co-authored a book called “Competing for the Future” in which they introduce the concepts of strategic intent ... strategic architecture, and then to help “build” that future. According to Hamel and Prahalad , a strategic architecture is a “high-level blueprint for the...Figure 6: Develop JIO Intellectual Leadership. It shows that the JIOST would be responsible for setting the Strategic Intent of our IO efforts

  18. Joint Task Force National Capital Region Medical: Integration of Education, Training, and Research

    DTIC Science & Technology

    2009-05-01

    Defense established the Joint Task Force National Capital Region Medical (JTF CapMed ) on the National Naval Medical Center campus in Bethesda, Maryland in...transfor- mation of military health services in the National Capital Area including education, training, and research activities. JTF CAPMED ...BACKGROUND JTF CapMed was established to lead the integration of mili- tary health care in the National Capital Region. The Command is charged with overseeing

  19. Space Suit Joint Torque Measurement Method Validation

    NASA Technical Reports Server (NTRS)

    Valish, Dana; Eversley, Karina

    2012-01-01

    In 2009 and early 2010, a test method was developed and performed to quantify the torque required to manipulate joints in several existing operational and prototype space suits. This was done in an effort to develop joint torque requirements appropriate for a new Constellation Program space suit system. The same test method was levied on the Constellation space suit contractors to verify that their suit design met the requirements. However, because the original test was set up and conducted by a single test operator there was some question as to whether this method was repeatable enough to be considered a standard verification method for Constellation or other future development programs. In order to validate the method itself, a representative subset of the previous test was repeated, using the same information that would be available to space suit contractors, but set up and conducted by someone not familiar with the previous test. The resultant data was compared using graphical and statistical analysis; the results indicated a significant variance in values reported for a subset of the re-tested joints. Potential variables that could have affected the data were identified and a third round of testing was conducted in an attempt to eliminate and/or quantify the effects of these variables. The results of the third test effort will be used to determine whether or not the proposed joint torque methodology can be applied to future space suit development contracts.

  20. Three-Dimensional Geometric Nonlinear Contact Stress Analysis of Riveted Joints

    NASA Technical Reports Server (NTRS)

    Shivakumar, Kunigal N.; Ramanujapuram, Vivek

    1998-01-01

    The problems associated with fatigue were brought into the forefront of research by the explosive decompression and structural failure of the Aloha Airlines Flight 243 in 1988. The structural failure of this airplane has been attributed to debonding and multiple cracking along the longitudinal lap splice riveted joint in the fuselage. This crash created what may be termed as a minor "Structural Integrity Revolution" in the commercial transport industry. Major steps have been taken by the manufacturers, operators and authorities to improve the structural airworthiness of the aging fleet of airplanes. Notwithstanding, this considerable effort there are still outstanding issues and concerns related to the formulation of Widespread Fatigue Damage which is believed to have been a contributing factor in the probable cause of the Aloha accident. The lesson from this accident was that Multiple-Site Damage (MSD) in "aging" aircraft can lead to extensive aircraft damage. A strong candidate in which MSD is highly probable to occur is the riveted lap joint.

  1. Joint China-United States Report for Year 1 Insulation Materials and Systems Project Area Clean Energy Research Center Building Energy Efficiency (CERC-BEE)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stovall, Therese K; Biswas, Kaushik; Song, Bo

    In November of 2009, the presidents of China and the U.S. announced the establishment of the Clean Energy Research Center (CERC). This broad research effort is co-funded by both countries and involves a large number of research centers and universities in both countries. One part of this program is focused on improving the energy efficiency of buildings. One portion of the CERC-BEE was focused on building insulation systems. The research objective of this effort was to Identify and investigate candidate high performance fire resistant building insulation technologies that meet the goal of building code compliance for exterior wall applications inmore » green buildings in multiple climate zones. A Joint Work Plan was established between researchers at the China Academy of Building Research and Oak Ridge National Laboratory. Efforts in the first year under this plan focused on information gathering. The objective of this research program is to reduce building energy use in China via improved building insulation technology. In cold regions in China, residents often use inefficient heating systems to provide a minimal comfort level within inefficient buildings. In warmer regions, air conditioning has not been commonly used. As living standards rise, energy consumption in these regions will increase dramatically unless significant improvements are made in building energy performance. Previous efforts that defined the current state of the built environment in China and in the U.S. will be used in this research. In countries around the world, building improvements have typically followed the implementation of more stringent building codes. There have been several changes in building codes in both the U.S. and China within the last few years. New U.S. building codes have increased the amount of wall insulation required in new buildings. New government statements from multiple agencies in China have recently changed the requirements for buildings in terms of energy

  2. Summary Report of Summer 2009 NGSI Human Capital Development Efforts at Lawrence Livermore National Laboratory

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dougan, A; Dreicer, M; Essner, J

    2009-11-16

    In 2009, Lawrence Livermore National Laboratory (LLNL) engaged in several activities to support NA-24's Next Generation Safeguards Initiative (NGSI). This report outlines LLNL's efforts to support Human Capital Development (HCD), one of five key components of NGSI managed by Dunbar Lockwood in the Office of International Regimes and Agreements (NA-243). There were five main LLNL summer safeguards HCD efforts sponsored by NGSI: (1) A joint Monterey Institute of International Studies/Center for Nonproliferation Studies-LLNL International Safeguards Policy and Information Analysis Course; (2) A Summer Safeguards Policy Internship Program at LLNL; (3) A Training in Environmental Sample Analysis for IAEA Safeguards Internship;more » (4) Safeguards Technology Internships; and (5) A joint LLNL-INL Summer Safeguards Lecture Series. In this report, we provide an overview of these five initiatives, an analysis of lessons learned, an update on the NGSI FY09 post-doc, and an update on students who participated in previous NGSI-sponsored LLNL safeguards HCD efforts.« less

  3. The Disestablishment of U.S. Joint Forces Command: A Step Backward in Jointness

    DTIC Science & Technology

    2011-06-01

    and the less than stellar 1983 rescue of a few medical students from the island of Grenada (Operation Urgent Fury), Congress passed the Goldwater...an opportunity for dialogue and a source of basic joint doctrine, it was widely ignored despite increasing tension and preparation for the Second... basic unity of effort appeared lacking even with dialogue like the Key West Agreements. Dr. William Niskanen, with the CATO Institute, described the

  4. Joint Institute for Nanoscience Annual Report 2003

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Baer, Donald R.; Campbell, Charles

    2004-02-01

    The Joint Institute for Nanoscience (JIN) is a cooperative venture of the University of Washington and Pacific Northwest National Laboratory to encourage and enhance high-impact and high-quality nanoscience and nanotechnology of all types. This first annual report for the JIN summarizes activities beginning in 2001 and ending at the close of fiscal year 2003 and therefore represents somewhat less than two years of activities. Major portions of the JIN resources are dedicated to funding graduate students and postdoctoral research associates to perform research in collaborations jointly directed by Pacific Northwest National Laboratory (PNNL) staff scientists and University of Washington (UW)more » professors. These fellowships were awarded on the basis of applications that included research proposals. JIN co-sponsors an annual Nanoscale Science and Technology Workshop held in Seattle. In addition to involving PNNL staff in various UW nanoscience courses and seminars, a National Science Foundation grant Development of UW-PNL Collaborative Curriculums in Nano-Science and Technology has allowed the development of three intensive short courses that are taught by UW faculty, PNNL staff, and faculty from other institutions, including Washington State University, the University of Idaho, Stanford University, and the University of Alaska. The initial JIN agreement recognized that expansion of cooperation beyond UW and PNNL would be highly valuable. Starting in early 2003, efforts were initiated to form a regional communication link called the Northwest Nanoscience and Nanotechnology Network (N₄). In concept, N₄ is a tool to encourage communication and help identify regional resources and nanoscience and technology activities.« less

  5. Shoe collar height effect on athletic performance, ankle joint kinematics and kinetics during unanticipated maximum-effort side-cutting performance.

    PubMed

    Lam, Gilbert Wing Kai; Park, Eun Jung; Lee, Ki-Kwang; Cheung, Jason Tak-Man

    2015-01-01

    Side-step cutting manoeuvres comprise the coordination between planting and non-planting legs. Increased shoe collar height is expected to influence ankle biomechanics of both legs and possibly respective cutting performance. This study examined the shoe collar height effect on kinematics and kinetics of planting and non-planting legs during an unanticipated side-step cutting. Fifteen university basketball players performed maximum-effort side-step cutting to the left 45° direction or a straight ahead run in response to a random light signal. Seven successful cutting trials were collected for each condition. Athletic performance, ground reaction force, ankle kinematics and kinetics of both legs were analysed using paired t-tests. Results indicated that high-collar shoes resulted in less ankle inversion and external rotation during initial contact for the planting leg. The high-collar shoes also exhibited a smaller ankle range of motion in the sagittal and transverse planes for both legs, respectively. However, no collar effect was found for ankle moments and performance indicators including cutting performance time, ground contact time, propulsion ground reaction forces and impulses. These findings indicated that high-collar shoes altered ankle positioning and restricted ankle joint freedom movements in both legs, while no negative effect was found for athletic cutting performance.

  6. Overview of NASA's Propulsion 21 Effort

    NASA Technical Reports Server (NTRS)

    Long-Davis, Mary Jo

    2006-01-01

    Propulsion 21 technologies contribute to reducing CO2 and NO(x) emissions and noise. Integrated Government/Industry/University research efforts have produced promising initial technical results. Graduate students from 5 partnering universities will benefit from this collaborative research--> educating the future engineering workforce. Phase 2 Efforts scheduled to be completed 3QFY06.

  7. The relation between residual stress, interfacial structure and the joint property in the SiO2f/SiO2-Nb joints.

    PubMed

    Ma, Qiang; Li, Zhuo Ran; Yang, Lai Shan; Lin, Jing Huang; Ba, Jin; Wang, Ze Yu; Qi, Jun Lei; Feng, Ji Cai

    2017-06-23

    In order to achieve a high-quality joint between SiO 2f /SiO 2 and metals, it is necessary to address the poor wettability of SiO 2f /SiO 2 and the high residual stress in SiO 2f /SiO 2 -Nb joint. Here, we simultaneously realize good wettability and low residual stress in SiO 2f /SiO 2 -Nb joint by combined method of HF etching treatment and Finite Element Analysis (FEA). After etching treatment, the wettability of E-SiO 2f /SiO 2 was improved, and the residual stress in the joint was decreased. In order to better control the quality of joints, efforts were made to understand the relationship between surface structure of E-SiO 2f /SiO 2 and residual stress in joint using FEA. Based on the direction of FEA results, a relationship between residual stress, surface structure and joint property in the brazed joints were investigated by experiments. As well the FEA and the brazing test results both realized the high-quality joint of E-SiO 2f /SiO 2 -Nb and the shear strength of the joint reached 61.9 MPa.

  8. The cyclic fatigue behavior of adhesive joints

    NASA Astrophysics Data System (ADS)

    Kinloch, A. J.; Toh, T.

    1995-06-01

    In the last six months we have: (1) Concentrated our efforts on the fatigue failure of carbon-fiber PEEK/AFl63 lap joints, and in particular we have started to predict the life time of single-lap joints under cyclic fatigue loading. The analysis is based on data obtained from double cantilever beam (DCB) fracture mechanics tests; (2) Further, we have been successful in measuring the rate of crack growth in lap joints during fatigue fracture using ultrasonic scanning; (3) Preliminary test data on the static fracture of glass-fiber reinforced poly(phenylene sulphide) (PPS)/AF163 joints have also been studied; and (4) A comparison has been made in computing the critical strain energy release rate G(sub c) for the glass-fiber PPS/AF163 joints based on the compliance method, beam theory and corrected beam theory. The last method accounts for large non-linear deflections and the associated crack root rotations along with the necessary corrections for the increase in stiffness introduced by the presence of end blocks.

  9. Research on the Implementation of the NASA Joint Sponsored Research Program and other Innovative Mechanism for Commercializing NASA Funded Technologies

    NASA Technical Reports Server (NTRS)

    Robbins, Karen Risa

    1997-01-01

    A goal of the ERAST Program is the commercial application of technology resulting from the work if the ERAST Alliance. This goal is sufficiently primary to be called out in the recitals section of the ERAST Joint Sponsored Research Agreement. In support of this goal, two activities described below were commenced in 1996 to assess and explore commercial applications of UAV technologies relevant to the ERAST Alliance.

  10. Research Review: Social motivation and oxytocin in autism – implications for joint attention development and intervention

    PubMed Central

    Stavropoulos, Katherine K. M.; Carver, Leslie J.

    2013-01-01

    Background and Scope The social motivation hypothesis (SMH) suggests that individuals with autism spectrum disorders (ASD) are less intrinsically rewarded by social stimuli than their neurotypical peers. This difference in social motivation has been posited as a factor contributing to social deficits in ASD. Social motivation is thought to involve the neuropeptide oxytocin. Here, we review the evidence for oxytocin effects in ASD, and discuss its potential role in one important social cognitive behavior. Methods Systematic searches were conducted using the PsychINFO and MEDLINE databases and the search terms “oxytocin”, and “autism”; the same databases were used for separate searches for “joint attention”, “intervention”, and “autism”, using the same inclusion criteria as an earlier 2011 review but updating it for the period 2010 to October 2012. Findings Several studies suggest that giving oxytocin to both individuals with ASD and typically developing individuals can enhance performance on social cognitive tasks. Studies that have attempted to intervene in joint attention in ASD suggest that social motivation may be a particular obstacle to lasting effects. Conclusions The review of the evidence for the SMH suggests a potential role for oxytocin in social motivation deficits in ASD. Because of its importance for later communicative and social development, the focus here is on implications of oxytocin and social motivation in the development of and interventions in joint attention. Joint attention is a central impairment in ASD, and as a result is the focus of several behavioral interventions. In describing this previous research on joint attention interventions in ASD, we pay particular attention to problems encountered in such studies, and propose ways that oxytocin may facilitate behavioral intervention in this area. For future research, integrating behavioral and pharmacological interventions (oxytocin administration) would be a worthwhile

  11. Research on adaptive optics image restoration algorithm based on improved joint maximum a posteriori method

    NASA Astrophysics Data System (ADS)

    Zhang, Lijuan; Li, Yang; Wang, Junnan; Liu, Ying

    2018-03-01

    In this paper, we propose a point spread function (PSF) reconstruction method and joint maximum a posteriori (JMAP) estimation method for the adaptive optics image restoration. Using the JMAP method as the basic principle, we establish the joint log likelihood function of multi-frame adaptive optics (AO) images based on the image Gaussian noise models. To begin with, combining the observed conditions and AO system characteristics, a predicted PSF model for the wavefront phase effect is developed; then, we build up iterative solution formulas of the AO image based on our proposed algorithm, addressing the implementation process of multi-frame AO images joint deconvolution method. We conduct a series of experiments on simulated and real degraded AO images to evaluate our proposed algorithm. Compared with the Wiener iterative blind deconvolution (Wiener-IBD) algorithm and Richardson-Lucy IBD algorithm, our algorithm has better restoration effects including higher peak signal-to-noise ratio ( PSNR) and Laplacian sum ( LS) value than the others. The research results have a certain application values for actual AO image restoration.

  12. Research on Microstructure and Properties of Welded Joint of High Strength Steel

    NASA Astrophysics Data System (ADS)

    Zhu, Pengxiao; Li, Yi; Chen, Bo; Ma, Xuejiao; Zhang, Dongya; Tang, Cai

    2018-01-01

    BS960 steel plates were welded by Laser-MAG and MAG. The microstructure and properties of the welded joints were investigated by optical microscope, micro-hardness tester, universal tensile testing machine, impact tester, scanning electron microscope (SEM) and fatigue tester. By a series of experiments, the following results were obtained: The grain size of the coarse grain zone with Laser-MAG welded joint is 20μm, and that with MAG welded joint is about 32μm, both of the fine grain region are composed of fine lath martensite and granular bainite; the width of the heat affected region with Laser-MAG is lower than that with MAG. The strength and impact energy of welded joints with Laser-MAG is higher than that with MAG. The conditioned fatigue limit of welded joint with Laser-MAG is 280MPa; however, the conditioned fatigue limit of welded joint with MAG is 250MPa.

  13. 2012 U.S. Department of Energy: Joint Genome Institute: Progress Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gilbert, David

    2013-01-01

    The mission of the U.S. Department of Energy Joint Genome Institute (DOE JGI) is to serve the diverse scientific community as a user facility, enabling the application of large-scale genomics and analysis of plants, microbes, and communities of microbes to address the DOE mission goals in bioenergy and the environment. The DOE JGI's sequencing efforts fall under the Eukaryote Super Program, which includes the Plant and Fungal Genomics Programs; and the Prokaryote Super Program, which includes the Microbial Genomics and Metagenomics Programs. In 2012, several projects made news for their contributions to energy and environment research.

  14. The joint flanker effect and the joint Simon effect: On the comparability of processes underlying joint compatibility effects.

    PubMed

    Dittrich, Kerstin; Bossert, Marie-Luise; Rothe-Wulf, Annelie; Klauer, Karl Christoph

    2017-09-01

    Previous studies observed compatibility effects in different interference paradigms such as the Simon and flanker task even when the task was distributed across two co-actors. In both Simon and flanker tasks, performance is improved in compatible trials relative to incompatible trials if one actor works on the task alone as well as if two co-actors share the task. These findings have been taken to indicate that actors automatically co-represent their co-actor's task. However, recent research on the joint Simon and joint flanker effect suggests alternative non-social interpretations. To which degree both joint effects are driven by the same underlying processes is the question of the present study, and it was scrutinized by manipulating the visibility of the co-actor. While the joint Simon effect was not affected by the visibility of the co-actor, the joint flanker effect was reduced when participants did not see their co-actors but knew where the co-actors were seated. These findings provide further evidence for a spatial interpretation of the joint Simon effect. In contrast to recent claims, however, we propose a new explanation of the joint flanker effect that attributes the effect to an impairment in the focusing of spatial attention contingent on the visibility of the co-actor.

  15. Numerical analysis and experimental research of the rubber boot of the joint drive vehicle

    NASA Astrophysics Data System (ADS)

    Ziobro, Jan

    2016-04-01

    The article presents many numerical studies and experimental research of the drive rubber boot of the joint drive vehicle. Performance requirements have been discussed and the required coefficients of the mathematical model for numerical simulation have been determined. The behavior of living in MSC.MARC environment was examined. In the analysis the following have been used: hyperplastic two-parameter model of the Mooney-Rivlin material, large displacements procedure, safe contact condition, friction on the sides of the boots. 3D numerical model of the joint bootwas analyzed under influence of the forces: tensile, compressive, centrifugal and angular. Numerous results of studies have been presented. An appropriate test stand was built and comparison of the results of the numerical analysis and the results of experimental studies was made. Numerous requests and recommendations for utilitarian character have been presented.

  16. Pressure relief and other joint rehabilitation techniques

    DOT National Transportation Integrated Search

    1987-02-01

    A study of four major concrete pavement joint rehabilitation techniques has been conducted, including: pressure relief joints, full-depth repairs, partial-depth repairs and joint resealing. The products of this research include the following for each...

  17. National High Frequency Radar Network (hfrnet) and Pacific Research Efforts

    NASA Astrophysics Data System (ADS)

    Hazard, L.; Terrill, E. J.; Cook, T.; de Paolo, T.; Otero, M. P.; Rogowski, P.; Schramek, T. A.

    2016-12-01

    The U.S. High Frequency Radar Network (HFRNet) has been in operation for over ten years with representation from 31 organizations spanning academic institutions, state and local government agencies, and private organizations. HFRNet currently holds a collection from over 130 radar installations totaling over 10 million records of surface ocean velocity measurements. HFRNet is a primary example of inter-agency and inter-institutional partnerships for improving oceanographic research and operations. HF radar derived surface currents have been used in several societal applications including coastal search and rescue, oil spill response, water quality monitoring and marine navigation. Central to the operational success of the large scale network is an efficient data management, storage, access, and delivery system. The networking of surface current mapping systems is characterized by a tiered structure that extends from the individual field installations to local regional operations maintaining multiple sites and on to centralized locations aggregating data from all regions. The data system development effort focuses on building robust data communications from remote field locations (sites) for ingestion into the data system via data on-ramps (Portals or Site Aggregators) to centralized data repositories (Nodes). Centralized surface current data enables the aggregation of national surface current grids and allows for ingestion into displays, management tools, and models. The Coastal Observing Research and Development Center has been involved in international relationships and research in the Philippines, Palau, and Vietnam. CORDC extends this IT architecture of surface current mapping data systems leveraging existing developments and furthering standardization of data services for seamless integration of higher level applications. Collaborations include the Philippine Atmospheric Geophysical and Astronomical Services Administration (PAGASA), The Coral Reef Research

  18. Boom and chassis articulation joints

    NASA Technical Reports Server (NTRS)

    Murphy, Joel T., Jr.; Nguyen, Vien; Turner, Bonnie; Wheeler, Bobby; Williams, Kimberlyn

    1992-01-01

    The primary goal of our design project was to develop articulation joints for the chassis and boom of the proof-of-concept lunar vehicle. This is an ongoing project and the work of previous student groups was extensively reviewed. Some of the ideas generated are variations of past proposals. Although the project is funded by NASA/USRA, it is totally a student design effort.

  19. Description of and preliminary tests results for the Joint Damping Experiment (JDX)

    NASA Technical Reports Server (NTRS)

    Bingham, Jeffrey G.; Folkman, Steven L.

    1995-01-01

    An effort is currently underway to develop an experiment titled joint Damping E_periment (JDX) to fly on the Space Shuttle as Get Away Special Payload G-726. This project is funded by NASA's IN-Space Technology Experiments Program and is scheduled to fly in July 1995 on STS-69. JDX will measure the influence of gravity on the structural damping of a three bay truss having clearance fit pinned joints. Structural damping is an important parameter in the dynamics of space structures. Future space structures will require more precise knowledge of structural damping than is currently available. The mission objectives are to develop a small-scale shuttle flight experiment that allows researchers to: (1) characterize the influence of gravity and joint gaps on structural damping and dynamic behavior of a small-scale truss model, and (2) evaluate the applicability of low-g aircraft test results for predicting on-orbit behavior. Completing the above objectives will allow a better understanding and/or prediction of structural damping occurring in a pin jointed truss. Predicting damping in joints is quite difficult. One of the important variables influencing joint damping is gravity. Previous work has shown that gravity loads can influence damping in a pin jointed truss structure. Flying this experiment as a GAS payload will allow testing in a microgravity environment. The on-orbit data (in micro-gravity) will be compared with ground test results. These data will be used to help develop improved models to predict damping due to pinned joints. Ground and low-g aircraft testing of this experiment has been completed. This paper describes the experiment and presents results of both ground and low-g aircraft tests which demonstrate that damping of the truss is dramatically influenced by gravity.

  20. Brief report: reconstruction of joint hyaline cartilage by autologous progenitor cells derived from ear elastic cartilage.

    PubMed

    Mizuno, Mitsuru; Kobayashi, Shinji; Takebe, Takanori; Kan, Hiroomi; Yabuki, Yuichiro; Matsuzaki, Takahisa; Yoshikawa, Hiroshi Y; Nakabayashi, Seiichiro; Ik, Lee Jeong; Maegawa, Jiro; Taniguchi, Hideki

    2014-03-01

    In healthy joints, hyaline cartilage covering the joint surfaces of bones provides cushioning due to its unique mechanical properties. However, because of its limited regenerative capacity, age- and sports-related injuries to this tissue may lead to degenerative arthropathies, prompting researchers to investigate a variety of cell sources. We recently succeeded in isolating human cartilage progenitor cells from ear elastic cartilage. Human cartilage progenitor cells have high chondrogenic and proliferative potential to form elastic cartilage with long-term tissue maintenance. However, it is unknown whether ear-derived cartilage progenitor cells can be used to reconstruct hyaline cartilage, which has different mechanical and histological properties from elastic cartilage. In our efforts to develop foundational technologies for joint hyaline cartilage repair and reconstruction, we conducted this study to obtain an answer to this question. We created an experimental canine model of knee joint cartilage damage, transplanted ear-derived autologous cartilage progenitor cells. The reconstructed cartilage was rich in proteoglycans and showed unique histological characteristics similar to joint hyaline cartilage. In addition, mechanical properties of the reconstructed tissues were higher than those of ear cartilage and equal to those of joint hyaline cartilage. This study suggested that joint hyaline cartilage was reconstructed from ear-derived cartilage progenitor cells. It also demonstrated that ear-derived cartilage progenitor cells, which can be harvested by a minimally invasive method, would be useful for reconstructing joint hyaline cartilage in patients with degenerative arthropathies. © AlphaMed Press.

  1. Report from the Third Annual Symposium of the RIKEN-Max Planck Joint Research Center for Systems Chemical Biology.

    PubMed

    Brunschweiger, Andreas

    2014-08-15

    The third Annual Symposium of the RIKEN-Max Planck Joint Research Center for Systems Chemical Biology was held at Ringberg castle, May 21-24, 2014. At this meeting 45 scientists from Japan and Germany presented the latest results from their research spanning a broad range of topics in chemical biology and glycobiology.

  2. Flaw Tolerance In Lap Shear Brazed Joints. Part 2

    NASA Technical Reports Server (NTRS)

    Wang, Len; Flom, Yury

    2003-01-01

    This paper presents results of the second part of an on-going effort to gain better understanding of defect tolerance in braze joints. In the first part of this three-part series, we mechanically tested and modeled the strength of the lap joints as a function of the overlap distance. A failure criterion was established based on the zone damage theory, which predicts the dependence of the lap joint shear strength on the overlap distance, based on the critical size of a finite damage zone or an overloaded region in the joint. In this second part of the study, we experimentally verified the applicability of the damage zone criterion on prediction of the shear strength of the lap joint and introduced controlled flaws into the lap joints. The purpose of the study was to evaluate the lap joint strength as a function of flaw size and its location through mechanical testing and nonlinear finite element analysis (FEA) employing damage zone criterion for definition of failure. The results obtained from the second part of the investigation confirmed that the failure of the ductile lap shear brazed joints occurs when the damage zone reaches approximately 10% of the overlap width. The same failure criterion was applicable to the lap joints containing flaws.

  3. Research for Change: the role of scientific journals publishing mental health research

    PubMed Central

    Saxena, Shekhar; Sharan, Pratap; Saraceno, Benedetto

    2004-01-01

    There is an enormous gap between the burden of mental disorders and mental health resources in low- and middle-income countries. The Mental Health: Global Action Programme of the World Health Organization (WHO) envisions an active role for research in the multidimensional efforts required to change the current mental health situation in these countries (Research for Change). WHO's strategies to achieve this include developing a research policy and a priority agenda at country level with active collaboration from all stakeholders, building research capacity and infrastructure and involving scientific journals to stimulate and disseminate public health oriented research. A recently agreed joint statement by editors of prominent journals publishing mental health research and WHO sets major objectives and some possible strategies for achieving this. WHO is committed to making Research for Change a reality by working with partners who share this aim. PMID:16633460

  4. Research for Change: the role of scientific journals publishing mental health research.

    PubMed

    Saxena, Shekhar; Sharan, Pratap; Saraceno, Benedetto

    2004-06-01

    There is an enormous gap between the burden of mental disorders and mental health resources in low- and middle-income countries. The Mental Health: Global Action Programme of the World Health Organization (WHO) envisions an active role for research in the multidimensional efforts required to change the current mental health situation in these countries (Research for Change). WHO's strategies to achieve this include developing a research policy and a priority agenda at country level with active collaboration from all stakeholders, building research capacity and infrastructure and involving scientific journals to stimulate and disseminate public health oriented research. A recently agreed joint statement by editors of prominent journals publishing mental health research and WHO sets major objectives and some possible strategies for achieving this. WHO is committed to making Research for Change a reality by working with partners who share this aim.

  5. Ankle moment generation and maximum-effort curved sprinting performance.

    PubMed

    Luo, Geng; Stefanyshyn, Darren

    2012-11-15

    Turning at high speed along acute curves is crucial for athletic performance. One determinant of curved sprinting speed is the ground reaction force that can be created by the supporting limb; the moment generated at the ankle joint may influence such force generation. Body lean associated with curved sprints positions the ankle joints in extreme in-/eversion, and may hinder the ankle moment generation. To examine the influence of ankle moment generation on curved sprinting performance, 17 male subjects performed maximum-effort curved sprints in footwear with and without a wedge. The wedged footwear was constructed with the intention to align the ankle joints closer to their neutral frontal-plane configuration during counter-clockwise curved sprints so greater joint moments might be generated. We found, with the wedged footwear, the average eversion angle of the inside leg ankle was reduced, and the plantarflexion moment generation increased significantly. Meanwhile, the knee extension moment remained unchanged. With the wedged footwear, stance-average centripetal ground reaction force increased significantly while no difference in the vertical ground reaction force was detected. The subjects created a greater centripetal ground reaction impulse in the wedged footwear despite a shortened stance phase when compared to the control. Stance-average curved sprinting speed improved by 4.3% with the wedged footwear. The changes in ankle moment and curved sprinting speed observed in the current study supports the notion that the moment generation at the ankle joint may be a performance constraint for curved sprinting. Copyright © 2012 Elsevier Ltd. All rights reserved.

  6. A Research Reactor Concept to Support NTP Development

    NASA Technical Reports Server (NTRS)

    Eades, Michael J.; Blue, T. E.; Gerrish, Harold P.; Hardin, Leroy A.

    2014-01-01

    In support of efforts for research into the design and development of man rated Nuclear Thermal Propulsion (NTP), the National Aeronautics and Space Administration (NASA), Marshall Space Flight Center (MSFC), is evaluating the potential for building a Nuclear Regulatory Commission (NRC) licensed NTP based research reactor (NTPRR). The proposed NTPRR would be licensed by NASA and operated jointly by NASA and university partners. The purpose of the NTPRR would be used to perform further research into the technologies and systems needed for a successful NTP project and promote nuclear training and education.

  7. The German joint research project "concepts for future gravity satellite missions"

    NASA Astrophysics Data System (ADS)

    Reubelt, Tilo; Sneeuw, Nico; Fichter, Walter; Müller, Jürgen

    2010-05-01

    Within the German joint research project "concepts for future gravity satellite missions", funded by the Geotechnologies programme of the German Federal Ministry of Education and Research, options and concepts for future satellite missions for precise (time-variable) gravity field recovery are investigated. The project team is composed of members from science and industry, bringing together experts in geodesy, satellite systems, metrology, sensor technology and control systems. The majority of team members already contributed to former gravity missions. The composition of the team guarantees that not only geodetic aspects and objectives are investigated, but also technological and financial constraints are considered. Conversely, satellite, sensor and system concepts are developed and improved in a direct exchange with geodetic and scientific claims. The project aims to develop concepts for both near and mid-term future satellite missions, taking into account e.g. advanced satellite formations and constellations, improved orbit design, innovative metrology and sensor systems and advances in satellite systems.

  8. Efforts to Bridge the Gap between Research and Practice in Social Work: Precedents and Prospects: Keynote Address at the Bridging the Gap Symposium

    ERIC Educational Resources Information Center

    Rubin, Allen

    2015-01-01

    This keynote address discusses previous and ongoing efforts to reduce the persistent gap between research and practice in social work and offers recommendations for further bridging that gap. Key among those recommendations is the need to conduct descriptive outcome studies of efforts to adapt research-supported interventions in everyday practice…

  9. New Horizons Launch Contingency Effort

    NASA Astrophysics Data System (ADS)

    Chang, Yale; Lear, Matthew H.; McGrath, Brian E.; Heyler, Gene A.; Takashima, Naruhisa; Owings, W. Donald

    2007-01-01

    On 19 January 2006 at 2:00 PM EST, the NASA New Horizons spacecraft (SC) was launched from the Cape Canaveral Air Force Station (CCAFS), FL, onboard an Atlas V 551/Centaur/STAR™ 48B launch vehicle (LV) on a mission to explore the Pluto Charon planetary system and possibly other Kuiper Belt Objects. It carried a single Radioisotope Thermoelectric Generator (RTG). As part of the joint NASA/US Department of Energy (DOE) safety effort, contingency plans were prepared to address the unlikely events of launch accidents leading to a near-pad impact, a suborbital reentry, an orbital reentry, or a heliocentric orbit. As the implementing organization. The Johns Hopkins University Applied Physics Laboratory (JHU/APL) had expanded roles in the New Horizons launch contingency effort over those for the Cassini mission and Mars Exploration Rovers missions. The expanded tasks included participation in the Radiological Control Center (RADCC) at the Kennedy Space Center (KSC), preparation of contingency plans, coordination of space tracking assets, improved aerodynamics characterization of the RTG's 18 General Purpose Heat Source (GPHS) modules, and development of spacecraft and RTG reentry breakup analysis tools. Other JHU/APL tasks were prediction of the Earth impact footprints (ElFs) for the GPHS modules released during the atmospheric reentry (for purposes of notification and recovery), prediction of the time of SC reentry from a potential orbital decay, pre-launch dissemination of ballistic coefficients of various possible reentry configurations, and launch support of an Emergency Operations Center (EOC) on the JHU/APL campus. For the New Horizons launch, JHU/APL personnel at the RADCC and at the EOC were ready to implement any real-time launch contingency activities. A successful New Horizons launch and interplanetary injection precluded any further contingency actions. The New Horizons launch contingency was an interagency effort by several organizations. This paper

  10. Static and Fatigue Strength Evaluations for Bolted Composite/Steel Joints for Heavy Vehicle Chassis Components

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sun, Xin; Stephens, Elizabeth V.; Herling, Darrell R.

    2004-09-14

    In May 2003, ORNL and PNNL began collaboration on a four year research effort focused on developing joining techniques to overcome the technical issues associated with joining lightweight materials in heavy vehicles. The initial focus of research is the development and validation of joint designs for a composite structural member attached to a metal member that satisfy the structural requirements both economically and reliably. Huck-bolting is a common joining method currently used in heavy truck chassis structures. The initial round of testing was conducted to establish a performance benchmark by evaluating the static and fatigue behavior of an existing steel/steelmore » chassis joint at the single huck-bolt level. Both tension and shear loading conditions were considered, and the resulting static and fatigue strengths will be used to guide the joint design for a replacement composite/steel joint. A commercially available, pultruded composite material was chosen to study the generic issues related to composite/steel joints. Extren is produced by STRONGWELL, and it is a combination of fiberglass reinforcement and thermosetting polyester or vinyl ester resin systems. Extren sheets of 3.2 mm thick were joined to 1.4 mm SAE1008 steel sheets with a standard grade 5 bolt with 6.35 mm diameter. Both tension and shear loading modes were considered for the single hybrid joint under static and fatigue loading conditions. Since fiberglass reinforced thermoset polymer composites are a non-homogenous material, their strengths and behavior are dependent upon the design of the composite and reinforcement. The Extren sheet stock was cut along the longitudinal direction to achieve maximum net-section strength. The effects of various manufacturing factors and operational conditions on the static and fatigue strength of the hybrid joint were modeled and experimentally verified. It was found that loading mode and washer size have significant influence on the static and fatigue

  11. Effects of joints in truss structures

    NASA Technical Reports Server (NTRS)

    Ikegami, R.

    1988-01-01

    The response of truss-type structures for future space applications, such as Large Deployable Reflector (LDR), will be directly affected by joint performance. Some of the objectives of research at BAC were to characterize structural joints, establish analytical approaches that incorporate joint characteristics, and experimentally establish the validity of the analytical approaches. The test approach to characterize joints for both erectable and deployable-type structures was based upon a Force State Mapping Technique. The approach pictorially shows how the nonlinear joint results can be used for equivalent linear analysis. Testing of the Space Station joints developed at LaRC (a hinged joint at 2 Hz and a clevis joint at 2 Hz) successfully revealed the nonlinear characteristics of the joints. The Space Station joints were effectively linear when loaded to plus or minus 500 pounds with a corresponding displacement of about plus or minus 0.0015 inch. It was indicated that good linear joints exist which are compatible with errected structures, but that difficulty may be encountered if nonlinear-type joints are incorporated in the structure.

  12. MO-FG-BRC-00: Joint AAPM-ESTRO Symposium: Advances in Experimental Medical Physics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    Experimental research in medical physics has expanded the limits of our knowledge and provided novel imaging and therapy technologies for patients around the world. However, experimental efforts are challenging due to constraints in funding, space, time and other forms of institutional support. In this joint ESTRO-AAPM symposium, four exciting experimental projects from four different countries are highlighted. Each project is focused on a different aspect of radiation therapy. From the USA, we will hear about a new linear accelerator concept for more compact and efficient therapy devices. From Canada, we will learn about novel linear accelerator target design and themore » implications for imaging and therapy. From France, we will discover a mature translational effort to incorporate theranostic nanoparticles in MR-guided radiation therapy. From Germany, we will find out about a novel in-treatment imaging modality for particle therapy. These examples of high impact, experimental medical physics research are representative of the diversity of such efforts that are on-going around the globe. J. Robar, Research is supported through collaboration with Varian Medical Systems and Brainlab AGD. Westerly, This work is supported by the Department of Radiation Oncology at the University of Colorado School of Medicine. COI: NONEK. Parodi, Part of the presented work is supported by the DFG (German Research Foundation) Cluster of Excellence MAP (Munich-Centre for Advanced Photonics) and has been carried out in collaboration with IBA.« less

  13. Choosing sheep (Ovis aries) as animal model for temporomandibular joint research: Morphological, histological and biomechanical characterization of the joint disc.

    PubMed

    Angelo, D F; Morouço, P; Alves, N; Viana, T; Santos, F; González, R; Monje, F; Macias, D; Carrapiço, B; Sousa, R; Cavaco-Gonçalves, S; Salvado, F; Peleteiro, C; Pinho, M

    2016-12-01

    Preclinical trials are essential to the development of scientific technologies. Remarkable molecular and cellular research has been done using small animal models. However, significant differences exist regarding the articular behavior between these models and humans. Thus, large animal models may be more appropriate to perform trials involving the temporomandibular joint (TMJ). The aim of this work was to make a morphological (anatomic dissection and white light 3D scanning system), histological (TMJ in bloc was removed for histologic analysis) and biomechanical characterization (tension and compression tests) of sheep TMJ comparing the obtained results with human data. Results showed that sheep processus condylaris and fossa mandibularis are anatomically similar to the same human structures. TMJ disc has an elliptical perimeter, thinner in the center than in periphery. Peripheral area acts as a ring structure supporting the central zone. The disc cells display both fibroblast and chondrocyte-like morphology. Marginal area is formed by loose connective tissue, with some chondrocyte-like cells and collagen fibers in diverse orientations. Discs obtained a tensile modulus of 3.97±0.73MPa and 9.39±1.67MPa, for anteroposterior and mediolateral assessment. The TMJ discs presented a compressive modulus (E) of 446.41±5.16MPa and their maximum stress value (σmax) was 18.87±1.33MPa. Obtained results suggest that these animals should be considered as a prime model for TMJ research and procedural training. Further investigations in the field of oromaxillofacial surgery involving TMJ should consider sheep as a good animal model due to its resemblance of the same joint in humans. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

  14. Theoretical Foundations and a Research Agenda to Validate Measures of Intercultural Effort

    ERIC Educational Resources Information Center

    Dowd, Alicia C.; Sawatzky, Misty; Korn, Randi

    2011-01-01

    The concept of "student effort" is foundational to such commonly used assessments of institutional effectiveness as the National Survey of Student Engagement (NSSE) and the Community College Survey of Student Engagement (CCSSE). However, the current measure of student effort omits intercultural effort, which is particularly salient to the academic…

  15. The mechanoreceptors of the costo-vertebral joints

    PubMed Central

    Godwin-Austen, R. B.

    1969-01-01

    1. Unitary recording in the thoracic dorsal roots of mechanoreceptor discharges from the costo-vertebral joints was carried out in the cat and rabbit. Criteria for the identification of costo-vertebral joint mechanoreceptors were established. 2. The majority of rib joint mechanoreceptors are slowly adapting and fifty-three such receptors were studied. Five rapidly adapting receptors were also identified. 3. The responses of these receptors have been correlated with rib position and movement. The slowly adapting receptors gave a monotonic response to different rib positions. 72% showed an increase of discharge rate with displacements towards expiratory rib positions. 4. In response to manually imposed rib movements slowly adapting joint mechanoreceptors gave a dynamic response which was directly related to the velocity of the movement and adapted within 2 sec. The movements of breathing produced a corresponding alteration of the discharge frequency of the slowly adapting receptors. 5. Slowly adapting receptors were localized to the capsule of the costo-transverse joint by probing. They responded to increased intra-articular pressure with an increase of discharge rate and were silenced by intra-articular lignocaine, 0·4%. 6. Rapidly adapting joint mechanoreceptors responded to rib movement with a brief burst of discharges. 7. The rib joint mechanoreceptors signal rib joint position, and the direction and velocity of rib movement. It is suggested that these afferent discharges provide the basis for the perception of respiratory movements of the chest. The significance of these receptors to the `sense of effort' resulting from a resistance to breathing is discussed. PMID:5789947

  16. Physiological effects of oral glucosamine on joint health: current status and consensus on future research priorities

    PubMed Central

    2013-01-01

    The aim of this paper was to provide an overview of the current knowledge and understanding of the potential beneficial physiological effects of glucosamine (GlcN) on joint health. The objective was to reach a consensus on four critical questions and to provide recommendations for future research priorities. To this end, nine scientists from Europe and the United States were selected according to their expertise in this particular field and were invited to participate in the Hohenheim conference held in August 2011. Each expert was asked to address a question that had previously been posed by the chairman of the conference. Based on a systematic review of the literature and the collection of recent data, the experts documented the effects of GlcN on cartilage ageing, metabolic/kinetic and maintenance of joint health as well as reduction of risk of OA development. After extensive debate and discussion the expert panel addressed each question and a general consensus statement was developed, agreeing on the current state-of-the-art and future areas for basic and clinical studies. This paper summarizes the available evidence for beneficial effects of GlcN on joint health and proposes new insight into the design of future clinical trials aimed at identifying beneficial physiological effect of GlcN on joint tissues. PMID:23531101

  17. Building a Quality Workforce. A Joint Initiative.

    ERIC Educational Resources Information Center

    Department of Commerce, Washington, DC.

    For this joint effort among three Cabinet Agencies, studies by a variety of organizations were reviewed and 134 business leaders and 34 education leaders in many communities throughout the United States were interviewed to determine what businesses find lacking among new entrants into the labor force and what employers' work force needs will be in…

  18. Sharing Technology for a Joint-Use Library

    ERIC Educational Resources Information Center

    Woods, Richard F.

    2004-01-01

    Building joint-use libraries to foster new types of learning and collaboration is a growing phenomenon that is of great interest to academic library planners around the world. Noteworthy among these efforts, the Dr. Martin Luther King, Jr. Library in San Jose, California, is a collaboration of a metropolitan university library and a major public…

  19. Pressure relief and other joint rehabilitation techniques : appendices

    DOT National Transportation Integrated Search

    1987-02-01

    Appendices of a study of four major concrete pavement joint rehabilitation techniques has been conducted, including: pressure relief joints, full-depth repairs, partial-depth repairs and joint resealing. The products of this research include the foll...

  20. Solar research in the Third Reich

    NASA Astrophysics Data System (ADS)

    Seiler, Michael P.

    Within the six years of the Second World War, German solar research succeeded in advancing from a mere provincial backwater to the forefront of this science. This has to be attributed to the joint effort of two very different men: Hans Plendl (1900-1991), a seasoned researcher who was a key figure in devising precision bombing aids for the Luftwaffe and who would eventually become Field Marshal Göring's Plenipotentiary for High Frequency Research before finally falling in disgrace, and Karl-Otto Kiepenheuer (1910-1975), a charismatic young astrophysicist, the son of a renowned publisher whose books were burned when the Nazi party came to power in 1933.

  1. Gulf Coast Joint Venture - Contact Us

    Science.gov Websites

    Contact us Gulf Coast Joint Venture Wetland and Aquatic Research Center 700 Cajundome Blvd. Lafayette, LA Coast Joint Venture - 700 Cajundome Blvd. - Lafayette, LA 70506 Phone: 337-266-8801 Fax: 337-266-8800

  2. A Research Graph dataset for connecting research data repositories using RD-Switchboard.

    PubMed

    Aryani, Amir; Poblet, Marta; Unsworth, Kathryn; Wang, Jingbo; Evans, Ben; Devaraju, Anusuriya; Hausstein, Brigitte; Klas, Claus-Peter; Zapilko, Benjamin; Kaplun, Samuele

    2018-05-29

    This paper describes the open access graph dataset that shows the connections between Dryad, CERN, ANDS and other international data repositories to publications and grants across multiple research data infrastructures. The graph dataset was created using the Research Graph data model and the Research Data Switchboard (RD-Switchboard), a collaborative project by the Research Data Alliance DDRI Working Group (DDRI WG) with the aim to discover and connect the related research datasets based on publication co-authorship or jointly funded grants. The graph dataset allows researchers to trace and follow the paths to understanding a body of work. By mapping the links between research datasets and related resources, the graph dataset improves both their discovery and visibility, while avoiding duplicate efforts in data creation. Ultimately, the linked datasets may spur novel ideas, facilitate reproducibility and re-use in new applications, stimulate combinatorial creativity, and foster collaborations across institutions.

  3. A Potential NASA Research Reactor to Support NTR Development

    NASA Technical Reports Server (NTRS)

    Eades, Michael; Gerrish, Harold; Hardin, Leroy

    2013-01-01

    In support of efforts for research into the design and development of a man rated Nuclear Thermal Rocket (NTR) engine, the National Aeronautics and Space Administration (NASA), Marshall Space Flight Center (MSFC), is evaluating the potential for building a Nuclear Regulatory Commission (NRC) licensed research reactor. The proposed reactor would be licensed by NASA and operated jointly by NASA and university partners. The purpose of this reactor would be to perform further research into the technologies and systems needed for a successful NTR project and promote nuclear training and education.

  4. Community-Engaged Strategies to Promote Relevance of Research Capacity-Building Efforts Targeting Community Organizations.

    PubMed

    Cunningham, Jennifer; Miller, Stephania T; Joosten, Yvonne; Elzey, Jared D; Israel, Tiffany; King, Christine; Luther, Patrick; Vaughn, Yolanda; Wilkins, Consuelo H

    2015-10-01

    The study goal is to highlight strategies for promoting relevance of research capacity-building efforts targeting community organizations (CO)s. Two community partners, representing two COs, were invited to participate in CO research development trainings, Community Research Forums (Forum)s. Their contributions were documented via Forum document review. Forum participants, representatives from other COs, completed post-Forum surveys to identify additional training needs and rate Forum impact relative to their training expectations. A content-based analysis and descriptive statistics were used to summarize needs assessment- and impact-related survey responses, respectively. Community partners were involved in eight Forum-related activities including marketing (planning), facilitation (implementation), and manuscript coauthorship (dissemination). Eighty-one individuals, representing 55 COs, attended the Forums. Needs assessment responses revealed a desire for additional assistance with existing Forum topics (e.g., defining research priorities) and a need for new ones (e.g., promoting organizational buy in for research). Ninety-one percent of participants agreed that the Forum demonstrated the value of research to COs and how to create a research agenda. Including community partners in all Forum phases ensured that CO perspectives were integrated throughout. Post-Forum needs and impact assessment results will help in tailoring, where needed, future training topics and strategies, respectively. © 2015 Wiley Periodicals, Inc.

  5. Discrimination of Closely-Spaced Geosynchronous Satellites - Phase Curve Analysis & New Small Business Innovative Research (SBIR) Efforts

    DTIC Science & Technology

    2010-09-01

    Discrimination of Closely-Spaced Geosynchronous Satellites – Phase Curve Analysis & New Small Business Innovative Research (SBIR) Efforts...such objects from one time epoch to another showcases the deficiencies in associating individual objects before and after the configuration change...1]) have emphasized examples of multiple satellites occupying the same geosynchronous slot, with individual satellites maneuvering about one another

  6. Increasing the international visibility of research data by a joint metadata schema

    NASA Astrophysics Data System (ADS)

    Svoboda, Nikolai; Zoarder, Muquit; Gärtner, Philipp; Hoffmann, Carsten; Heinrich, Uwe

    2017-04-01

    The BonaRes Project ("Soil as a sustainable resource for the bioeconomy") was launched in 2015 to promote sustainable soil management and to avoid fragmentation of efforts (Wollschläger et al., 2016). For this purpose, an IT infrastructure is being developed to upload, manage, store, and provide research data and its associated metadata. The research data provided by the BonaRes data centre are, in principle, not subject to any restrictions on reuse. For all research data considerable standardized metadata are the key enablers for the effective use of these data. Providing proper metadata is often viewed as an extra burden with further work and resources consumed. In our lecture we underline the benefits of structured and interoperable metadata like: accessibility of data, discovery of data, interpretation of data, linking data and several more and we counter these advantages with the effort of time, personnel and further costs. Building on this, we describe the framework of metadata in BonaRes combining the standards of OGC for description, visualization, exchange and discovery of geodata as well as the schema of DataCite for the publication and citation of this research data. This enables the generation of a DOI, a unique identifier that provides a permanent link to the citable research data. By using OGC standards, data and metadata become interoperable with numerous research data provided via INSPIRE. It enables further services like CSW for harvesting WMS for visualization and WFS for downloading. We explain the mandatory fields that result from our approach and we give a general overview about our metadata architecture implementation. Literature: Wollschläger, U; Helming, K.; Heinrich, U.; Bartke, S.; Kögel-Knabner, I.; Russell, D.; Eberhardt, E. & Vogel, H.-J.: The BonaRes Centre - A virtual institute for soil research in the context of a sustainable bio-economy. Geophysical Research Abstracts, Vol. 18, EGU2016-9087, 2016.

  7. Oxide dispersion strengthened ferritic steels: a basic research joint program in France

    NASA Astrophysics Data System (ADS)

    Boutard, J.-L.; Badjeck, V.; Barguet, L.; Barouh, C.; Bhattacharya, A.; Colignon, Y.; Hatzoglou, C.; Loyer-Prost, M.; Rouffié, A. L.; Sallez, N.; Salmon-Legagneur, H.; Schuler, T.

    2014-12-01

    AREVA, CEA, CNRS, EDF and Mécachrome are funding a joint program of basic research on Oxide Dispersion Strengthened Steels (ODISSEE), in support to the development of oxide dispersion strengthened 9-14% Cr ferritic-martensitic steels for the fuel element cladding of future Sodium-cooled fast neutron reactors. The selected objectives and the results obtained so far will be presented concerning (i) physical-chemical characterisation of the nano-clusters as a function of ball-milling process, metallurgical conditions and irradiation, (ii) meso-scale understanding of failure mechanisms under dynamic loading and creep, and, (iii) kinetic modelling of nano-clusters nucleation and α/α‧ unmixing.

  8. Recent Efforts in Communications Research and Technology at the Glenn Research Center in Support of NASA's Mission

    NASA Technical Reports Server (NTRS)

    Miranda, Felix A.

    2015-01-01

    As it has done in the past, NASA is currently engaged in furthering the frontiers of space and planetary exploration. The effectiveness in gathering the desired science data in the amount and quality required to perform this pioneering work relies heavily on the communications capabilities of the spacecraft and space platforms being considered to enable future missions. Accordingly, the continuous improvement and development of radiofrequency and optical communications systems are fundamental to prevent communications to become the limiting factor for space explorations. This presentation will discuss some of the research and technology development efforts currently underway at the NASA Glenn Research Center in the radio frequency (RF) and Optical Communications. Examples of work conducted in-house and also in collaboration with academia, industry, and other government agencies (OGA) in areas such as antenna technology, power amplifiers, radio frequency (RF) wave propagation through Earths atmosphere, ultra-sensitive receivers, thin films ferroelectric-based tunable components, among others, will be presented. In addition, the role of these and other related RF technologies in enabling the NASA next generation space communications architecture will be also discussed.

  9. Basic and Applied Materials Science Research Efforts at MSFC Germane to NASA Goals

    NASA Technical Reports Server (NTRS)

    2003-01-01

    Presently, a number of investigations are ongoing that blend basic research with engineering applications in support of NASA goals. These include (1) "Pore Formation and Mobility (PFMI) " An ISS Glovebox Investigation" NASA Selected Project - 400-34-3D; (2) "Interactions Between Rotating Bodies" Center Director's Discretionary Fund (CDDF) Project - 279-62-00-16; (3) "Molybdenum - Rhenium (Mo-Re) Alloys for Nuclear Fuel Containment" TD Collaboration - 800-11-02; (4) "Fabrication of Alumina - Metal Composites for Propulsion Components" ED Collaboration - 090-50-10; (5) "Radiation Shielding for Deep-Space Missions" SD Effort; (6) "Other Research". In brief, "Pore Formation and Mobility" is an experiment to be conducted in the ISS Microgravity Science Glovebox that will systematically investigate the development, movement, and interactions of bubbles (porosity) during the controlled directional solidification of a transparent material. In addition to promoting our general knowledge of porosity physics, this work will serve as a guide to future ISS experiments utilizing metal alloys. "Interactions Between Rotating Bodies" is a CDDF sponsored project that is critically examining, through theory and experiment, claims of "new" physics relating to gravity modification and electric field effects. "Molybdenum - Rhenium Alloys for Nuclear Fuel Containment" is a TD collaboration in support of nuclear propulsion. Mo-Re alloys are being evaluated and developed for nuclear fuel containment. "Fabrication of Alumina - Metal Composites for Propulsion Components" is an ED collaboration with the intent of increasing strength and decreasing weight of metal engine components through the incorporation of nanometer-sized alumina fibers. "Radiation Shielding for Deep-Space Missions" is an SD effort aimed at minimizing the health risk from radiation to human space voyagers; work to date has been primarily programmatic but experiments to develop hydrogen-rich materials for shielding are

  10. NDE research efforts at the FAA Center for Aviation Systems Reliability

    NASA Technical Reports Server (NTRS)

    Thompson, Donald O.; Brasche, Lisa J. H.

    1992-01-01

    The Federal Aviation Administration-Center for Aviation Systems Reliability (FAA-CASR), a part of the Institute for Physical Research and Technology at Iowa State University, began operation in the Fall of 1990 with funding from the FAA. The mission of the FAA-CASR is to develop quantitative nondestructive evaluation (NDE) methods for aircraft structures and materials including prototype instrumentation, software, techniques, and procedures and to develop and maintain comprehensive education and training programs in aviation specific inspection procedures and practices. To accomplish this mission, FAA-CASR brings together resources from universities, government, and industry to develop a comprehensive approach to problems specific to the aviation industry. The problem areas are targeted by the FAA, aviation manufacturers, the airline industry and other members of the aviation business community. This consortium approach ensures that the focus of the efforts is on relevant problems and also facilitates effective transfer of the results to industry.

  11. Extremity war injuries: collaborative efforts in research, host nation care, and disaster preparedness.

    PubMed

    Pollak, Andrew N; Ficke, Col James R

    2010-01-01

    The fourth annual Extremity War Injuries (EWI) Symposium addressed ongoing challenges and opportunities in the management of combat-related musculoskeletal injury. The symposium, which also examined host-nation care and disaster preparedness and response, defined opportunities for synergy between several organizations with similar missions and goals. Within the Department of Defense, the Orthopaedic Extremity Trauma Research Program (OETRP) has funded basic research related to a series of protocols first identified and validated at prior EWI symposia. A well-funded clinical research arm of OETRP has been developed to help translate and validate research advances from each of the protocols. The Armed Forces Institute for Regenerative Medicine, a consortium of academic research institutions, employs a tissue-engineering approach to EWI challenges, particularly with regard to tissue loss. Programs within the National Institute of Arthritis and Musculoskeletal and Skin Diseases and throughout the National Institutes of Health have also expanded tissue-engineering efforts by emphasizing robust mechanistic basic science programs. Much of the clinical care delivered by US military medical personnel and nongovernmental agencies has been to host-nation populations; coordinating delivery to maximize the number of injured who receive care requires understanding of the breadth and scope of resources available within the war zone. Similarly, providing the most comprehensive care to the greatest number of injured in the context of domestic mass casualty requires discussion and planning by all groups involved.

  12. An Approach to the Internationalisation of the Curriculum: Sino-British Joint Efforts for Three Online Courses

    ERIC Educational Resources Information Center

    Yawan, Li; Ying, Li

    2011-01-01

    With a view to facilitating good practice and enhancing further exchanges and collaboration with the Open University UK, the Open University of China initiated a joint programme of training to offer online tutors and academic management staff three courses: Student Support, Tutoring On-line, and Course Design. The programme brought in not only a…

  13. Effort in Multitasking: Local and Global Assessment of Effort.

    PubMed

    Kiesel, Andrea; Dignath, David

    2017-01-01

    When performing multiple tasks in succession, self-organization of task order might be superior compared to external-controlled task schedules, because self-organization allows optimizing processing modes and thus reduces switch costs, and it increases commitment to task goals. However, self-organization is an additional executive control process that is not required if task order is externally specified and as such it is considered as time-consuming and effortful. To compare self-organized and externally controlled task scheduling, we suggest assessing global subjective and objectives measures of effort in addition to local performance measures. In our new experimental approach, we combined characteristics of dual tasking settings and task switching settings and compared local and global measures of effort in a condition with free choice of task sequence and a condition with cued task sequence. In a multi-tasking environment, participants chose the task order while the task requirement of the not-yet-performed task remained the same. This task preview allowed participants to work on the previously non-chosen items in parallel and resulted in faster responses and fewer errors in task switch trials than in task repetition trials. The free-choice group profited more from this task preview than the cued group when considering local performance measures. Nevertheless, the free-choice group invested more effort than the cued group when considering global measures. Thus, self-organization in task scheduling seems to be effortful even in conditions in which it is beneficiary for task processing. In a second experiment, we reduced the possibility of task preview for the not-yet-performed tasks in order to hinder efficient self-organization. Here neither local nor global measures revealed substantial differences between the free-choice and a cued task sequence condition. Based on the results of both experiments, we suggest that global assessment of effort in addition to

  14. Multilateral Biomedical Data Sharing in the One-year Joint US-Russian Mission on the International Space Station

    NASA Technical Reports Server (NTRS)

    Charles, John B.; Haven, C.; Johnson-Throop, K.; Van Baalen, M.; McFather, J.

    2014-01-01

    The One Year Mission (1YM) by two astronauts on the International Space Station (ISS), starting in March 2015, offers a unique opportunity to expand multilateral collaboration by sharing data and resources among the partner agencies in preparation for planned space exploration missions beyond low Earth orbit. Agreements and protocols will be established for the collection, distribution, analysis and reporting of both research and clinical data. Data will be shared between the agencies sponsoring the investigators, and between the research and clinical medicine communities where common interests are identified. The assignment of only two astronauts, one Russian and the other American, to the 1YM necessitated creativity in bilateral efforts to maximize the biomedical return from the opportunity. Addition of Canadian, European and Japanese investigations make the effort even more integrative. There will be three types of investigations: joint, cross-participation and data-exchange. The joint investigations have US and Russian coprincipal investigators, and the data acquired will be their common responsibility. The other two types must develop data sharing agreements and processes specific to their needs. A multilateral panel of ISS partner space agencies will develop policies for international exchange of scientific information to meet their science objectives and priorities. They will promote archiving of space flight data and will inform each other and the scientific community at large about the results obtained from space life sciences studies. Integration tasks for the 1YM are based on current experience from the ISS and previous efforts on the Russian space station Mir. Closer coordination between international partners requires more common approaches to remove barriers to multilateral resource utilization on the ISS. Greater integration in implementation should increase utilization efficiency to benefit all participants in spaceflight human research. This

  15. How joint torques affect hamstring injury risk in sprinting swing-stance transition.

    PubMed

    Sun, Yuliang; Wei, Shutao; Zhong, Yunjian; Fu, Weijie; Li, Li; Liu, Yu

    2015-02-01

    The potential mechanisms of hamstring strain injuries in athletes are not well understood. The study, therefore, was aimed at understanding hamstring mechanics by studying loading conditions during maximum-effort overground sprinting. Three-dimensional kinematics and ground reaction force data were collected from eight elite male sprinters sprinting at their maximum effort. Maximal isometric torques of the hip and knee were also collected. Data from the sprinting gait cycle were analyzed via an intersegmental dynamics approach, and the different joint torque components were calculated. During the initial stance phase, the ground reaction force passed anteriorly to the knee and hip, producing an extension torque at the knee and a flexion torque at the hip joint. Thus, the active muscle torque functioned to produce flexion torque at the knee and extension torque at the hip. The maximal muscle torque at the knee joint was 1.4 times the maximal isometric knee flexion torque. During the late swing phase, the muscle torque counterbalanced the motion-dependent torque and acted to flex the knee joint and extend the hip joint. The loading conditions on the hamstring muscles were similar to those of the initial stance phase. During both the initial stance and late swing phases, the large passive torques at both the knee and hip joints acted to lengthen the hamstring muscles. The active muscle torques generated mainly by the hamstrings functioned to counteract those passive effects. As a result, during sprinting or high-speed locomotion, the hamstring muscles may be more susceptible to high risk of strain injury during these two phases.

  16. Actuation for simultaneous motions and constraining efforts: an open chain example

    NASA Astrophysics Data System (ADS)

    Perreira, N. Duke

    1997-06-01

    A brief discussion on systems where simultaneous control of forces and velocities are desirable is given and an example linkage with revolute and prismatic joint is selected for further analysis. The Newton-Euler approach for dynamic system analysis is applied to the example to provide a basis of comparison. Gauge invariant transformations are used to convert the dynamic equations into invariant form suitable for use in a new dynamic system analysis method known as the motion-effort approach. This approach uses constraint elimination techniques based on singular value decompositions to recast the invariant form of dynamic system equations into orthogonal sets of motion and effort equations. Desired motions and constraining efforts are partitioned into ideally obtainable and unobtainable portions which are then used to determine the required actuation. The method is applied to the example system and an analytic estimate to its success is made.

  17. Research on Joint Sealant Materials to Improve Installation and Performance : Final Report

    DOT National Transportation Integrated Search

    2017-12-01

    The objectives of this project were to 1) identify failure modes and their mechanisms in joint seals in Texas, and to 2) identify what needs to be done to minimize the failures and improve joint seal performance. To achieve these objectives efficient...

  18. Knowledge Co-production at the Research-Practice Interface: Embedded Case Studies from Urban Forestry

    Treesearch

    Lindsay K. Campbell; Erika S. Svendsen; Lara A. Roman

    2016-01-01

    Cities are increasingly engaging in sustainability efforts and investment in green infrastructure, including large-scale urban tree planting campaigns. In this context, researchers and practitioners are working jointly to develop applicable knowledge for planning and managing the urban forest. This paper presents three case studies of knowledge co-production in the...

  19. Cooperative research in high energy astrophysics

    NASA Technical Reports Server (NTRS)

    1994-01-01

    Details of the activities conducted under the joint effort of the University of Maryland and NASA Goddard Space Flight Center Laboratory for High Energy Astrophysics are detailed for the period July 1989 through April 1994. The research covered a variety of topics including: (1) detection of cosmic rays and studies of the solar modulation of galactic cosmic rays; (2) support work for several x-ray satellites; (3) high resolution gamma-ray spectroscopy of celestial sources; (4)theoretical astrophysics; and (5) active galaxies.

  20. Report Summarizing the Effort Required to Initiate Welding of Irradiated Materials within the Welding Cubicle

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Frederick, Greg; Sutton, Benjamin J.; Tatman, Jonathan K.

    The advanced welding facility within a hot cell at the Radiochemical Engineering Development Center of Oak Ridge National Laboratory (ORNL), which has been jointly funded by the U.S. Department of Energy (DOE), Office of Nuclear Energy, Light Water Reactor Sustainability Program and the Electric Power Research Institute, Long Term Operations Program and the Welding and Repair Technology Center, is in the final phase of development. Research and development activities in this facility will involve direct testing of advanced welding technologies on irradiated materials in order to address the primary technical challenge of helium induced cracking that can arise when conventionalmore » fusion welding techniques are utilized on neutron irradiated stainless steels and nickel-base alloys. This report details the effort that has been required since the beginning of fiscal year 2017 to initiate welding research and development activities on irradiated materials within the hot cell cubicle, which houses welding sub-systems that include laser beam welding (LBW) and friction stir welding (FSW) and provides material containment within the hot cell.« less

  1. Surrogate Joint Aerial Layer Network (JALN) Experiment: Applications of Commercial-Off-The-Shelf Technologies for Researching Future JALN Challenges

    DTIC Science & Technology

    2014-12-01

    CHALLENGES DECEMBER 2014 TECHNICAL REPORT APPROVED FOR PUBLIC RELEASE; DISTRIBUTION UNLIMITED STINFO COPY AIR FORCE RESEARCH LABORATORY INFORMATION...JOINT AERIAL LAYER NETWORK (JALN) EXPERIMENT: APPLICATION OF COMMERCIAL-OFF-THE-SHELF TECHNOLOGIES FOR RESEARCHING FUTURE JALN CHALLENGES 5a... challenge JALN developers. The use of low-cost COTS wireless technology is found to be a suitable surrogate for military hardware for investigating

  2. Analysis of the Lenticular Jointed MARSIS Antenna Deployment

    NASA Technical Reports Server (NTRS)

    Mobrem, Mehran; Adams, Douglas S.

    2006-01-01

    This paper summarizes important milestones in a yearlong comprehensive effort which culminated in successful deployments of the MARSIS antenna booms in May and June of 2005. Experimentally measured straight section and hinge properties are incorporated into specialized modeling techniques that are used to simulate the boom lenticular joints. System level models are exercised to understand the boom deployment dynamics and spacecraft level implications. Discussion includes a comparison of ADAMS simulation results to measured flight data taken during the three boom deployments. Important parameters that govern lenticular joint behavior are outlined and a short summary of lessons learned and recommendations is included to better understand future applications of this technology.

  3. Tsinghua-Johns Hopkins Joint Center for Biomedical Engineering Research: scientific and cultural exchange in undergraduate engineering.

    PubMed

    Wisneski, Andrew D; Huang, Lixia; Hong, Bo; Wang, Xiaoqin

    2011-01-01

    A model for an international undergraduate biomedical engineering research exchange program is outlined. In 2008, the Johns Hopkins University in collaboration with Tsinghua University in Beijing, China established the Tsinghua-Johns Hopkins Joint Center for Biomedical Engineering Research. Undergraduate biomedical engineering students from both universities are offered the opportunity to participate in research at the overseas institution. Programs such as these will not only provide research experiences for undergraduates but valuable cultural exchange and enrichment as well. Currently, strict course scheduling and rigorous curricula in most biomedical engineering programs may present obstacles for students to partake in study abroad opportunities. Universities are encouraged to harbor abroad opportunities for undergraduate engineering students, for which this particular program can serve as a model.

  4. An Open-Source Toolbox for Surrogate Modeling of Joint Contact Mechanics

    PubMed Central

    Eskinazi, Ilan

    2016-01-01

    Goal Incorporation of elastic joint contact models into simulations of human movement could facilitate studying the interactions between muscles, ligaments, and bones. Unfortunately, elastic joint contact models are often too expensive computationally to be used within iterative simulation frameworks. This limitation can be overcome by using fast and accurate surrogate contact models that fit or interpolate input-output data sampled from existing elastic contact models. However, construction of surrogate contact models remains an arduous task. The aim of this paper is to introduce an open-source program called Surrogate Contact Modeling Toolbox (SCMT) that facilitates surrogate contact model creation, evaluation, and use. Methods SCMT interacts with the third party software FEBio to perform elastic contact analyses of finite element models and uses Matlab to train neural networks that fit the input-output contact data. SCMT features sample point generation for multiple domains, automated sampling, sample point filtering, and surrogate model training and testing. Results An overview of the software is presented along with two example applications. The first example demonstrates creation of surrogate contact models of artificial tibiofemoral and patellofemoral joints and evaluates their computational speed and accuracy, while the second demonstrates the use of surrogate contact models in a forward dynamic simulation of an open-chain leg extension-flexion motion. Conclusion SCMT facilitates the creation of computationally fast and accurate surrogate contact models. Additionally, it serves as a bridge between FEBio and OpenSim musculoskeletal modeling software. Significance Researchers may now create and deploy surrogate models of elastic joint contact with minimal effort. PMID:26186761

  5. 75 FR 20002 - Notice Pursuant to the National Cooperative Research and Production Act of 1993 Joint Venture...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-16

    ... demonstrate the production of low-cost, high-quality metallic and semiconducting single wall carbon nanotube... Production Act of 1993 Joint Venture Under Tip Award Number: 7ONANB1OHOO1 Notice is hereby given that, on February 3, 2010, pursuant to Section 6(a) of the National Cooperative Research and Production Act of 1993...

  6. Joint Hampton-Michigan Program for Training Minority and Women Researchers. Volume II of II Volumes. Final Report.

    ERIC Educational Resources Information Center

    Michigan Univ., Ann Arbor. School of Education.

    The papers presented in this volume are the team research reports of the Joint Hampton-Michigan Program conducted in 1979-1980 for junior faculty members of the Hampton Institute (Virginia) and graduate students and faculty members of the University of Michigan. The titles of the papers are: (1) Social and Economic Implications of Teacher Training…

  7. Low-Friction, High-Stiffness Joint for Uniaxial Load Cell

    NASA Technical Reports Server (NTRS)

    Lewis, James L.; Le, Thang; Carroll, Monty B.

    2007-01-01

    A universal-joint assembly has been devised for transferring axial tension or compression to a load cell. To maximize measurement accuracy, the assembly is required to minimize any moments and non-axial forces on the load cell and to exhibit little or no hysteresis. The requirement to minimize hysteresis translates to a requirement to maximize axial stiffness (including minimizing backlash) and a simultaneous requirement to minimize friction. In practice, these are competing requirements, encountered repeatedly in efforts to design universal joints. Often, universal-joint designs represent compromises between these requirements. The improved universal-joint assembly contains two universal joints, each containing two adjustable pairs of angular-contact ball bearings. One might be tempted to ask why one could not use simple ball-and-socket joints rather than something as complex as universal joints containing adjustable pairs of angularcontact ball bearings. The answer is that ball-and-socket joints do not offer sufficient latitude to trade stiffness versus friction: the inevitable result of an attempt to make such a trade in a ball-and-socket joint is either too much backlash or too much friction. The universal joints are located at opposite ends of an axial subassembly that contains the load cell. The axial subassembly includes an axial shaft, an axial housing, and a fifth adjustable pair of angular-contact ball bearings that allows rotation of the axial housing relative to the shaft. The preload on each pair of angular-contact ball bearings can be adjusted to obtain the required stiffness with minimal friction, tailored for a specific application. The universal joint at each end affords two degrees of freedom, allowing only axial force to reach the load cell regardless of application of moments and non-axial forces. The rotational joint on the axial subassembly affords a fifth degree of freedom, preventing application of a torsion load to the load cell.

  8. PLANNED INTEGRATION OF MEASUREMENT AND SURVEY DATA FROM THE DEARS WITH LOCAL AND REGIONAL RESEARCH EFFORTS: PRELIMINARY DATA FINDINGS AND OBSERVATIONS

    EPA Science Inventory

    The Canadian-US Border Air Quality Studies represent collaborative research being performed by both parties. This abstract details the efforts of the Detroit Exposure and Aerosol Research Study (DEARS) to work collaboratively in this regards. A discussion of the collaborations ...

  9. Torque Limit for Bolted Joint For Composites. Part B; Experimentation

    NASA Technical Reports Server (NTRS)

    Kostreva, Kristian M.

    2003-01-01

    Today, aerospace quality composite parts are generally made from either a unidirectional tape or a fabric prepreg form depending on the application. The matrix material, typically epoxy because of it dimensional stability, is pre-impregnated onto the fibers to ensure uniform distribution. Both of these composite forms are finding themselves used in applications where a joint is required. Two widely used joint methods are the classic mechanically fastened joint, and the contemporary bonded joint; however, the mechanically fastened joint is most commonly used by design engineers. A major portion of the research up-to-date about bolted composite joints has dealt with the inplane static load capacity. This work has helped to spawn standards dealing with filled-hole static joint strength. Other research has clearly shown that the clamp-up load in the mechanical fastener significantly affects the joint strength in a beneficial manner by reducing the bearing strength dependence of the composite laminate. One author reported a maximum increase in joint strength of 28%. This finding has helped to improve the reliability and efficiency of the joint in a composite structure.

  10. 75 FR 8116 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-Joint Venture...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-23

    ... Production Act of 1993--Joint Venture Under Tip Award No. 70NANB10H009 Notice is hereby given that, on January 15, 2010, pursuant to Section 6(a) of the National Cooperative Research and Production Act of 1993... technologies for high- speed scrap sortation of mixed metals by alloy type, and for real-time, molten metal...

  11. Study reveals potentially prognostic gene, metabolism changes in kidney cancers | Center for Cancer Research

    Cancer.gov

    The Cancer Genome Atlas Research Network investigators, including CCR scientists, identified genetic and metabolic pathway changes linked to reduced survival of patients within and across subtypes of renal cell carcinoma (RCC), a type of kidney cancer. The study, published April 5, 2018, in Cell Reports, is part of The Cancer Genome Atlas (TCGA) Program, a joint effort of the National Cancer Institute (NCI) and the National Human Genome Research Institute (NHGRI).

  12. Solder Joint Health Monitoring Testbed

    NASA Technical Reports Server (NTRS)

    Delaney, Michael M.; Flynn, James; Browder, Mark

    2009-01-01

    A method of monitoring the health of selected solder joints, called SJ-BIST, has been developed by Ridgetop Group Inc. under a Small Business Innovative Research (SBIR) contract. The primary goal of this research program is to test and validate this method in a flight environment using realistically seeded faults in selected solder joints. An additional objective is to gather environmental data for future development of physics-based and data-driven prognostics algorithms. A test board is being designed using a Xilinx FPGA. These boards will be tested both in flight and on the ground using a shaker table and an altitude chamber.

  13. Preliminary Design and Analysis of an In-plane PRSEUS Joint

    NASA Technical Reports Server (NTRS)

    Lovejoy, Andrew E.; Poplawski, Steven

    2013-01-01

    As part of the National Aeronautics and Space Administration's (NASA's) Environmentally Responsible Aviation (ERA) program, the Pultruded Rod Stitched Efficient Unitized Structure (PRSEUS) has been designed, developed and tested. However, PRSEUS development efforts to date have only addressed joints required to transfer bending moments between PRSEUS panels. Development of in-plane joints for the PRSEUS concept is necessary to facilitate in-plane transfer of load from PRSEUS panels to an adjacent structure, such as from a wing panel into a fuselage. This paper presents preliminary design and analysis of an in-plane PRSEUS joint for connecting PRSEUS panels at the termination of the rod-stiffened stringers. Design requirements are provided, the PRSEUS blade joint concept is presented, and preliminary design changes and analyses are carried out to examine the feasibility of the proposed in-plane PRSEUS blade joint. The study conducted herein focuses mainly on the PRSEUS structure on one side of the joint. In particular, the design requirements for the rod shear stress and bolt bearing stress are examined. A PRSEUS blade joint design was developed that demonstrates the feasibility of this in-plane PRSEUS joint concept to terminate the rod-stiffened stringers. The presented design only demonstrates feasibility, therefore, some areas of refinement are presented that would lead to a more optimum and realistic design.

  14. How Joint Torques Affect Hamstring Injury Risk in Sprinting Swing–Stance Transition

    PubMed Central

    SUN, YULIANG; WEI, SHUTAO; ZHONG, YUNJIAN; FU, WEIJIE; LI, LI; LIU, YU

    2015-01-01

    ABSTRACT Purpose The potential mechanisms of hamstring strain injuries in athletes are not well understood. The study, therefore, was aimed at understanding hamstring mechanics by studying loading conditions during maximum-effort overground sprinting. Methods Three-dimensional kinematics and ground reaction force data were collected from eight elite male sprinters sprinting at their maximum effort. Maximal isometric torques of the hip and knee were also collected. Data from the sprinting gait cycle were analyzed via an intersegmental dynamics approach, and the different joint torque components were calculated. Results During the initial stance phase, the ground reaction force passed anteriorly to the knee and hip, producing an extension torque at the knee and a flexion torque at the hip joint. Thus, the active muscle torque functioned to produce flexion torque at the knee and extension torque at the hip. The maximal muscle torque at the knee joint was 1.4 times the maximal isometric knee flexion torque. During the late swing phase, the muscle torque counterbalanced the motion-dependent torque and acted to flex the knee joint and extend the hip joint. The loading conditions on the hamstring muscles were similar to those of the initial stance phase. Conclusions During both the initial stance and late swing phases, the large passive torques at both the knee and hip joints acted to lengthen the hamstring muscles. The active muscle torques generated mainly by the hamstrings functioned to counteract those passive effects. As a result, during sprinting or high-speed locomotion, the hamstring muscles may be more susceptible to high risk of strain injury during these two phases. PMID:24911288

  15. Combining traditional dietary assessment methods with novel metabolomics techniques: present efforts by the Food Biomarker Alliance.

    PubMed

    Brouwer-Brolsma, Elske M; Brennan, Lorraine; Drevon, Christian A; van Kranen, Henk; Manach, Claudine; Dragsted, Lars Ove; Roche, Helen M; Andres-Lacueva, Cristina; Bakker, Stephan J L; Bouwman, Jildau; Capozzi, Francesco; De Saeger, Sarah; Gundersen, Thomas E; Kolehmainen, Marjukka; Kulling, Sabine E; Landberg, Rikard; Linseisen, Jakob; Mattivi, Fulvio; Mensink, Ronald P; Scaccini, Cristina; Skurk, Thomas; Tetens, Inge; Vergeres, Guy; Wishart, David S; Scalbert, Augustin; Feskens, Edith J M

    2017-11-01

    FFQ, food diaries and 24 h recall methods represent the most commonly used dietary assessment tools in human studies on nutrition and health, but food intake biomarkers are assumed to provide a more objective reflection of intake. Unfortunately, very few of these biomarkers are sufficiently validated. This review provides an overview of food intake biomarker research and highlights present research efforts of the Joint Programming Initiative 'A Healthy Diet for a Healthy Life' (JPI-HDHL) Food Biomarkers Alliance (FoodBAll). In order to identify novel food intake biomarkers, the focus is on new food metabolomics techniques that allow the quantification of up to thousands of metabolites simultaneously, which may be applied in intervention and observational studies. As biomarkers are often influenced by various other factors than the food under investigation, FoodBAll developed a food intake biomarker quality and validity score aiming to assist the systematic evaluation of novel biomarkers. Moreover, to evaluate the applicability of nutritional biomarkers, studies are presently also focusing on associations between food intake biomarkers and diet-related disease risk. In order to be successful in these metabolomics studies, knowledge about available electronic metabolomics resources is necessary and further developments of these resources are essential. Ultimately, present efforts in this research area aim to advance quality control of traditional dietary assessment methods, advance compliance evaluation in nutritional intervention studies, and increase the significance of observational studies by investigating associations between nutrition and health.

  16. A Note on the Purposes, Development, and Applicability of the Joint Committee Evaluation Standards

    ERIC Educational Resources Information Center

    Stufflebeam, Daniel L.

    2004-01-01

    The past few years have seen efforts in several countries and a wide range of disciplines to adopt and apply existing professional standards for guiding and judging evaluation services and/or develop new standards. Some of the efforts have drawn from the work and products of the North American Joint Committee on Standards for Educational…

  17. Knee joint replacement

    MedlinePlus

    ... Knee joint replacement - series References American Academy of Orthopedic Surgeons (AAOS) website. Treatment of osteoarthritis of the knee: evidence-based guideline 2nd edition (summary) . www.aaos.org/research/guidelines/TreatmentofOsteoarthritisoftheKneeGuideline.pdf . Updated May 18, 2013. Accessed ...

  18. From Joint Experimentation to Laissez-Faire: Transdisciplinary Innovation Research for the Institutional Strengthening of a Water Users Association in Khorezm, Uzbekistan

    ERIC Educational Resources Information Center

    Djanibekov, Nodir; Hornidge, Anna-Katharina; Ul-Hassan, Mehmood

    2012-01-01

    Purpose: This article assesses a participatory action and innovation research experience, in which project researchers, farmers and staff members of a local water users association (WUA) came together to: (a) jointly test and adapt a social mobilization and institutional strengthening approach according to the local context, and by doing so, to…

  19. The Research and Training Activities for the Joint Institute for Aeronautics and Acoustics

    NASA Technical Reports Server (NTRS)

    Cantwell, Brian

    1995-01-01

    This proposal requests continued support for the program of activities to be undertaken by the Ames-Stanford Joint Institute for Aeronautics and Acoustics during the period 1 Oct. 1995 - 30 Sept. 1996. The emphasis in this program is on training and research in experimental and computational methods with application to aerodynamics, acoustics and the important interactions between them. The program comprises activities in active flow control, Large Eddy Simulation of jet noise, flap aerodynamics and acoustics and high lift modeling studies. During the proposed period there will be a continued emphasis on the interaction between NASA Ames, Stanford University and Industry, particularly in connection with the high lift activities.

  20. [Efforts to Promote Research Integrity in Academia].

    PubMed

    Yasui, Hiroyuki

    2018-01-01

     The revised model/core curriculum for pharmaceutical education in Japan was introduced in 2015. The need to provide ethics education, which includes research integrity for pharmacists and those conducting pharmaceutical research, was clearly described in the document: "G: pharmaceutical research (2) rule of law and ethics essential for research activity." Additionally, this newly introduced model/core curriculum was officially requested within each pharmaceutical university. As recently as 2014, a severe situation was exposed in the field of life sciences and clinical research: many reports emerged about scientific misconduct in Japan. The members of Kyoto Pharmaceutical University were deeply concerned about this situation and thus decided that our guidelines of action for research integrity would be approached as follows: All members of Kyoto Pharmaceutical University would individually rethink the university's research integrity and ethics with a strong sense of ownership and importance, discuss concrete countermeasures and future plans to establish our university's research integrity, and collectively implement these strategies through education programs. In this review, we introduce several examples of educational activities undertaken by our university, and use them as a basis for discussing how we should address research integrity and the responsible conduct of research in education for academics, graduate students, and undergraduates.

  1. Space Suit Joint Torque Testing

    NASA Technical Reports Server (NTRS)

    Valish, Dana J.

    2011-01-01

    In 2009 and early 2010, a test was performed to quantify the torque required to manipulate joints in several existing operational and prototype space suits in an effort to develop joint torque requirements appropriate for a new Constellation Program space suit system. The same test method was levied on the Constellation space suit contractors to verify that their suit design meets the requirements. However, because the original test was set up and conducted by a single test operator there was some question as to whether this method was repeatable enough to be considered a standard verification method for Constellation or other future space suits. In order to validate the method itself, a representative subset of the previous test was repeated, using the same information that would be available to space suit contractors, but set up and conducted by someone not familiar with the previous test. The resultant data was compared using graphical and statistical analysis and a variance in torque values for some of the tested joints was apparent. Potential variables that could have affected the data were identified and re-testing was conducted in an attempt to eliminate these variables. The results of the retest will be used to determine if further testing and modification is necessary before the method can be validated.

  2. Unloading joints to treat osteoarthritis, including joint distraction.

    PubMed

    Lafeber, Floris P J G; Intema, Femke; Van Roermund, Peter M; Marijnissen, Anne C A

    2006-09-01

    Patients are increasingly becoming interested in nonpharmacologic approaches to manage their osteoarthritis. This review examines the recent literature on the potential beneficial effects of unloading joints in the treatment of osteoarthritis, with a focus on joint distraction. Mechanical factors are involved in the development and progression of osteoarthritis. If "loading" is a major cause in development and progression of osteoarthritis, then "unloading" may be able to prevent progression. There is evidence that unloading may be effective in reducing pain and slowing down structural damage. This review describes unloading by footwear and bracing (nonsurgical), unloading by osteotomy (surgical), and has a focus on unloading by joint distraction. Excellent reviews in all these three fields have been published over the past few years. Recent studies argue for the usefulness of a biomechanical approach to improve function and possibly reduce disease progression in osteoarthritis. To improve patient function and possibly reduce disease progression, a biomechanical approach should be considered in treating patients with osteoarthritis. Further research (appropriate high-quality clinical trials) and analysis (clinical as well as preclinical and fundamental) are still necessary, however, to understand, validate, and refine the different approaches of unloading to treat osteoarthritis.

  3. Cooperative Engineering as a Joint Action

    ERIC Educational Resources Information Center

    Joffredo-Le Brun, Sophie; Morellato, Mireille; Sensevy, Gérard; Quilio, Serge

    2018-01-01

    This paper describes some elements of a specific kind of design-based research, cooperative engineering. In the first part of the paper, we argue that cooperative engineering can be analyzed through a joint action framework. We first present some conceptual tools that the Joint Action Theory in Didactics proposes in order to understand didactic…

  4. The Air Commander in the Solomon Islands Campaign: Unrivaled Unity of Effort in Joint Air Operations

    DTIC Science & Technology

    2011-06-01

    aircraft, and people in the Pacific, keeping the Allies on the defensive throughout Asia and the Pacific. Singapore and the Philippines ... Philippines and Australia during the course of the war.16 Each of these commanders fell under the direct oversight of the American Joint Chiefs of Staff...Miller, The War in the Pacific, 81-85. August 11 revealing his newfound but tardy understanding of the problem: “This island warfare is a tough

  5. Great Expectations in the Joint Advanced Manufacturing Region

    DTIC Science & Technology

    2016-12-01

    would be continuous experimentation and risk reduction prototyping. The entire manufacturing life cycle— design , testing, product development...on the back of a napkin, they decided to call their effort the Joint Advanced Manufacturing Region (JAMR) and manage it as an Integrated Product ... designed to support the continuous experimentation of advanced manufacturing tactics, tech- niques and procedures under actual operational or combat

  6. Anaerobic prosthetic joint infection.

    PubMed

    Shah, Neel B; Tande, Aaron J; Patel, Robin; Berbari, Elie F

    2015-12-01

    In an effort to improve mobility and alleviate pain from degenerative and connective tissue joint disease, an increasing number of individuals are undergoing prosthetic joint replacement in the United States. Joint replacement is a highly effective intervention, resulting in improved quality of life and increased independence [1]. By 2030, it is predicted that approximately 4 million total hip and knee arthroplasties will be performed yearly in the United States [2]. One of the major complications associated with this procedure is prosthetic joint infection (PJI), occurring at a rate of 1-2% [3-7]. In 2011, the Musculoskeletal Infectious Society created a unifying definition for prosthetic joint infection [8]. The following year, the Infectious Disease Society of America published practice guidelines that focused on the diagnosis and management of PJI. These guidelines focused on the management of commonly encountered organisms associated with PJI, including staphylococci, streptococci and select aerobic Gram-negative bacteria. However, with the exception of Propionibacterium acnes, management of other anaerobic organisms was not addressed in these guidelines [1]. Although making up approximately 3-6% of PJI [9,10], anaerobic microorganisms cause devastating complications, and similar to the more common organisms associated with PJI, these bacteria also result in significant morbidity, poor outcomes and increased health-care costs. Data on diagnosis and management of anaerobic PJI is mostly derived from case reports, along with a few cohort studies [3]. There is a paucity of published data outlining factors associated with risks, diagnosis and management of anaerobic PJI. We therefore reviewed available literature on anaerobic PJI by systematically searching the PubMed database, and collected data from secondary searches to determine information on pathogenesis, demographic data, clinical features, diagnosis and management. We focused our search on five commonly

  7. Study reveals potentially prognostic gene, metabolism changes in kidney cancers | Center for Cancer Research

    Cancer.gov

    The Cancer Genome Atlas Research Network investigators, including CCR scientists, identified genetic and metabolic pathway changes linked to reduced survival of patients within and across subtypes of renal cell carcinoma (RCC), a type of kidney cancer. The study, published April 5, 2018, in Cell Reports, is part of The Cancer Genome Atlas (TCGA) Program, a joint effort of the

  8. International Arctic Research Collaborations: Past, Present and Future

    NASA Astrophysics Data System (ADS)

    Kintisch, E. S.

    2015-12-01

    International cooperation on Arctic research has a long and storied history, predating even the first International Polar Year in 1881. But scientists want to improve and expand current efforts to conduct international Arctic research, despite politcal and legal barriers that can hamper it. A review of the past and present aspects of such research can inform that effort. As part of a six month fellowship at the Center for Science Diplomacy at the American Association for the Advancement of Science I studied the history and current status of international cooperation in the Arctic. I will report on my findings, which include the fact that some of the first substantial international environmental research and regulatory cooperation began in the far North. My session will identify the elements that make international research collaborations successful, for example more than a century of cooperative work by Russian and Norwegian fishery scientists to monitor and regulate the cod trade in the Barents Sea. And it will explore the challenges that can threaten such collaborations. These can include rules that stymie data collection, block the import of certain analytical equipment across national boundaries, and bar the export of soil or water samples. I will mention specific complications to recent international arctic research projects. These include the SWERUS cruise, a joint effort between Sweden, Russia and the US, an effort to study carbon fluxes over the East Siberian Arctic Shelf in 2014. The session will also review progress towards a new international agreeement, first proposed by the US, on improving arctic research cooperation. That deal is focused on removing the bureacratic and legal barriers to scientists seeking to conduct arctic research on foreign waters and land.

  9. Integrating qualitative research methods into care improvement efforts within a learning health system: addressing antibiotic overuse.

    PubMed

    Munoz-Plaza, Corrine E; Parry, Carla; Hahn, Erin E; Tang, Tania; Nguyen, Huong Q; Gould, Michael K; Kanter, Michael H; Sharp, Adam L

    2016-08-15

    Despite reports advocating for integration of research into healthcare delivery, scant literature exists describing how this can be accomplished. Examples highlighting application of qualitative research methods embedded into a healthcare system are particularly needed. This article describes the process and value of embedding qualitative research as the second phase of an explanatory, sequential, mixed methods study to improve antibiotic stewardship for acute sinusitis. Purposive sampling of providers for in-depth interviews improved understanding of unwarranted antibiotic prescribing and elicited stakeholder recommendations for improvement. Qualitative data collection, transcription and constant comparative analyses occurred iteratively. Emerging themes and sub-themes identified primary drivers of unwarranted antibiotic prescribing patterns and recommendations for improving practice. These findings informed the design of a health system intervention to improve antibiotic stewardship for acute sinusitis. Core components of the intervention are also described. Qualitative research can be effectively applied in learning healthcare systems to elucidate quantitative results and inform improvement efforts.

  10. Joint Decision No. KEP-235/MEN 1985 and No. 114/MENKES/SKB/111/1985 and Joint Decision No. KEP-333/MEN/1985 and No. 15/MENKES/SKB/IV/1985, 1985.

    PubMed

    1988-01-01

    Under these Joint Decisions, all industrial establishments employing 300 or more workers are obliged to establish an in-plant health clinic and to provide contraceptive services to eligible worker couples. Under Joint Decree No. KEP.12/MEN/1984 of the Ministry of Manpower, the Indonesian Labor Federation and the Indonesian Employers Association agreed to step up their family planning efforts in the industrial sector with the cooperation of the National Family Planning Coordinating Board. full text

  11. Joint Center for Satellite Data Assimilation Overview and Research Activities

    NASA Astrophysics Data System (ADS)

    Auligne, T.

    2017-12-01

    In 2001 NOAA/NESDIS, NOAA/NWS, NOAA/OAR, and NASA, subsequently joined by the US Navy and Air Force, came together to form the Joint Center for Satellite Data Assimilation (JCSDA) for the common purpose of accelerating the use of satellite data in environmental numerical prediction modeling by developing, using, and anticipating advances in numerical modeling, satellite-based remote sensing, and data assimilation methods. The primary focus was to bring these advances together to improve operational numerical model-based forecasting, under the premise that these partners have common technical and logistical challenges assimilating satellite observations into their modeling enterprises that could be better addressed through cooperative action and/or common solutions. Over the last 15 years, the JCSDA has made and continues to make major contributions to operational assimilation of satellite data. The JCSDA is a multi-agency U.S. government-owned-and-operated organization that was conceived as a venue for the several agencies NOAA, NASA, USAF and USN to collaborate on advancing the development and operational use of satellite observations into numerical model-based environmental analysis and forecasting. The primary mission of the JCSDA is to "accelerate and improve the quantitative use of research and operational satellite data in weather, ocean, climate and environmental analysis and prediction systems." This mission is fulfilled through directed research targeting the following key science objectives: Improved radiative transfer modeling; new instrument assimilation; assimilation of humidity, clouds, and precipitation observations; assimilation of land surface observations; assimilation of ocean surface observations; atmospheric composition; and chemistry and aerosols. The goal of this presentation is to briefly introduce the JCSDA's mission and vision, and to describe recent research activities across various JCSDA partners.

  12. Research on polar bears in Alaska, 1983-1985

    USGS Publications Warehouse

    Amstrup, Steven C.

    1986-01-01

    Research on the ecology and status of polar bear populations in Alaska has continued since 1967. Research was a joint U.S. Fish and Wildlife Service/Alaska Department of Fish and Game effort until passage of the Marine Mammal Protection Act in 1972, and has been largely a Federal effort since then. In 1985, Alaskan polar beer research continues to be carried out by the Research Division of the U.S. Fish and Wildlife Service (DOI). A recent reorganization removed authority for ecological research in Alaska from the Denver Wildlife Research Center, and vested it with the newly created Alaska Office of Fish and Wildlife Research. This new research office is the center for Federal fish and Wildlife related research throughout the state of Alaska and in its coastal waters.Although the responsibility for polar bear research lies with the U.S. Fish and Wildlife Service, numerous other organizations and agencies deserve mention for their cooperation and support of the ongoing research. These include: the U.S. National Oceanic and Atmospheric Administration (DOC), The U.S. Minerals Management Service (DOI), The Canadian Wildlife Service, The Northwest Territories Wildlife Service, the Yukon Wildlife Service, Dome Petroleum Ltd, Gulf Canada, and the Alaska Department of Fish and game.

  13. Body position reproducibility and joint alignment stability criticality on a muscular strength research device

    NASA Astrophysics Data System (ADS)

    Nunez, F.; Romero, A.; Clua, J.; Mas, J.; Tomas, A.; Catalan, A.; Castellsaguer, J.

    2005-08-01

    MARES (Muscle Atrophy Research and Exercise System) is a computerized ergometer for neuromuscular research to be flown and installed onboard the International Space Station in 2007. Validity of data acquired depends on controlling and reducing all significant error sources. One of them is the misalignment of the joint rotation axis with respect to the motor axis.The error induced on the measurements is proportional to the misalignment between both axis. Therefore, the restraint system's performance is critical [1]. MARES HRS (Human Restraint System) assures alignment within an acceptable range while performing the exercise (results: elbow movement:13.94mm+/-5.45, Knee movement: 22.36mm+/- 6.06 ) and reproducibility of human positioning (results: elbow movement: 2.82mm+/-1.56, Knee movement 7.45mm+/-4.8 ). These results allow limiting measurement errors induced by misalignment.

  14. Gait analysis and weight bearing in pre-clinical joint pain research.

    PubMed

    Ängeby Möller, Kristina; Svärd, Heta; Suominen, Anni; Immonen, Jarmo; Holappa, Johanna; Stenfors, Carina

    2018-04-15

    There is a need for better joint pain treatment, but development of new medication has not been successful. Pre-clinical models with readouts that better reflect the clinical situation are needed. In patients with joint pain, pain at rest and pain at walking are two major complaints. We describe a new way of calculating results from gait analysis using the CatWalk™ setup. Rats with monoarthritis induced by injection of Complete Freund's Adjuvant (CFA) intra-articularly into the ankle joint of one hind limb were used to assess gait and dynamic weight bearing. The results show that dynamic weight bearing was markedly reduced for the injected paw. Gait parameters such as amount of normal step sequences, walking speed and duration of step placement were also affected. Treatment with naproxen (an NSAID commonly used for inflammatory pain) attenuated the CFA-induced effects. Pregabalin, which is used for neuropathic pain, had no effect. Reduced dynamic weight bearing during locomotion, assessed and calculated in the way we present here, showed a dose-dependent and lasting normalization after naproxen treatment. In contrast, static weight bearing while standing (Incapacitance tester) showed a significant effect for a limited time only. Mechanical sensitivity (von Frey Optihairs) was completely normalized by naproxen, and the window for testing pharmacological effect disappeared. Objective and reproducible effects, with an endpoint showing face validity compared to pain while walking in patients with joint pain, are achieved by a new way of calculating dynamic weight bearing in monoarthritic rats. Copyright © 2017 Elsevier B.V. All rights reserved.

  15. Spherical Joint Piston and Connecting Rod Developed

    NASA Technical Reports Server (NTRS)

    1996-01-01

    Under an interagency agreement with the Department of Energy, the NASA Lewis Research Center manages a Heavy-Duty Diesel Engine Technology (HDET) research program. The overall program objectives are to reduce fuel consumption through increased engine efficiency, reduce engine exhaust emissions, and provide options for the use of alternative fuels. The program is administered with a balance of research contracts, university research grants, and focused in-house research. The Cummins Engine Company participates in the HDET program under a cost-sharing research contract. Cummins is researching and developing in-cylinder component technologies for heavy-duty diesel engines. An objective of the Cummins research is to develop technologies for a low-emissions, 55-percent thermal efficiency (LE-55) engine. The best current-production engines in this class achieve about 46-percent thermal efficiency. Federal emissions regulations are driving this technology. Regulations for heavy duty diesel engines were tightened in 1994, more demanding emissions regulations are scheduled for 1998, and another step is planned for 2002. The LE-55 engine emissions goal is set at half of the 1998 regulation level and is consistent with plans for 2002 emissions regulations. LE-55 engine design requirements to meet the efficiency target dictate a need to operate at higher peak cylinder pressures. A key technology being developed and evaluated under the Cummins Engine Company LE-55 engine concept is the spherical joint piston and connecting rod. Unlike conventional piston and connecting rod arrangements which are joined by a pin forming a hinged joint, the spherical joint piston and connecting rod use a ball-and-socket joint. The ball-and-socket arrangement enables the piston to have an axisymmetric design allowing rotation within the cylinder. The potential benefits of piston symmetry and rotation are reduced scuffing, improved piston ring sealing, improved lubrication, mechanical and thermal

  16. [Advances on biomechanics and kinematics of sprain of ankle joint].

    PubMed

    Zhao, Yong; Wang, Gang

    2015-04-01

    Ankle sprains are orthopedic clinical common disease, accounting for joint ligament sprain of the first place. If treatment is not timely or appropriate, the joint pain and instability maybe develop, and even bone arthritis maybe develop. The mechanism of injury of ankle joint, anatomical basis has been fully study at present, and the diagnostic problem is very clear. Along with the development of science and technology, biological modeling and three-dimensional finite element, three-dimensional motion capture system,digital technology study, electromyographic signal study were used for the basic research of sprain of ankle. Biomechanical and kinematic study of ankle sprain has received adequate attention, combined with the mechanism research of ankle sprain,and to explore the the biomechanics and kinematics research progress of the sprain of ankle joint.

  17. Tissue material properties and computational modelling of the human tibiofemoral joint: a critical review

    PubMed Central

    Akhtar, Riaz; Comerford, Eithne J.; Bates, Karl T.

    2018-01-01

    Understanding how structural and functional alterations of individual tissues impact on whole-joint function is challenging, particularly in humans where direct invasive experimentation is difficult. Finite element (FE) computational models produce quantitative predictions of the mechanical and physiological behaviour of multiple tissues simultaneously, thereby providing a means to study changes that occur through healthy ageing and disease such as osteoarthritis (OA). As a result, significant research investment has been placed in developing such models of the human knee. Previous work has highlighted that model predictions are highly sensitive to the various inputs used to build them, particularly the mathematical definition of material properties of biological tissues. The goal of this systematic review is two-fold. First, we provide a comprehensive summation and evaluation of existing linear elastic material property data for human tibiofemoral joint tissues, tabulating numerical values as a reference resource for future studies. Second, we review efforts to model tibiofemoral joint mechanical behaviour through FE modelling with particular focus on how studies have sourced tissue material properties. The last decade has seen a renaissance in material testing fuelled by development of a variety of new engineering techniques that allow the mechanical behaviour of both soft and hard tissues to be characterised at a spectrum of scales from nano- to bulk tissue level. As a result, there now exists an extremely broad range of published values for human tibiofemoral joint tissues. However, our systematic review highlights gaps and ambiguities that mean quantitative understanding of how tissue material properties alter with age and OA is limited. It is therefore currently challenging to construct FE models of the knee that are truly representative of a specific age or disease-state. Consequently, recent tibiofemoral joint FE models have been highly generic in terms of

  18. Tissue material properties and computational modelling of the human tibiofemoral joint: a critical review.

    PubMed

    Peters, Abby E; Akhtar, Riaz; Comerford, Eithne J; Bates, Karl T

    2018-01-01

    Understanding how structural and functional alterations of individual tissues impact on whole-joint function is challenging, particularly in humans where direct invasive experimentation is difficult. Finite element (FE) computational models produce quantitative predictions of the mechanical and physiological behaviour of multiple tissues simultaneously, thereby providing a means to study changes that occur through healthy ageing and disease such as osteoarthritis (OA). As a result, significant research investment has been placed in developing such models of the human knee. Previous work has highlighted that model predictions are highly sensitive to the various inputs used to build them, particularly the mathematical definition of material properties of biological tissues. The goal of this systematic review is two-fold. First, we provide a comprehensive summation and evaluation of existing linear elastic material property data for human tibiofemoral joint tissues, tabulating numerical values as a reference resource for future studies. Second, we review efforts to model tibiofemoral joint mechanical behaviour through FE modelling with particular focus on how studies have sourced tissue material properties. The last decade has seen a renaissance in material testing fuelled by development of a variety of new engineering techniques that allow the mechanical behaviour of both soft and hard tissues to be characterised at a spectrum of scales from nano- to bulk tissue level. As a result, there now exists an extremely broad range of published values for human tibiofemoral joint tissues. However, our systematic review highlights gaps and ambiguities that mean quantitative understanding of how tissue material properties alter with age and OA is limited. It is therefore currently challenging to construct FE models of the knee that are truly representative of a specific age or disease-state. Consequently, recent tibiofemoral joint FE models have been highly generic in terms of

  19. Toward a Rational and Mechanistic Account of Mental Effort.

    PubMed

    Shenhav, Amitai; Musslick, Sebastian; Lieder, Falk; Kool, Wouter; Griffiths, Thomas L; Cohen, Jonathan D; Botvinick, Matthew M

    2017-07-25

    In spite of its familiar phenomenology, the mechanistic basis for mental effort remains poorly understood. Although most researchers agree that mental effort is aversive and stems from limitations in our capacity to exercise cognitive control, it is unclear what gives rise to those limitations and why they result in an experience of control as costly. The presence of these control costs also raises further questions regarding how best to allocate mental effort to minimize those costs and maximize the attendant benefits. This review explores recent advances in computational modeling and empirical research aimed at addressing these questions at the level of psychological process and neural mechanism, examining both the limitations to mental effort exertion and how we manage those limited cognitive resources. We conclude by identifying remaining challenges for theoretical accounts of mental effort as well as possible applications of the available findings to understanding the causes of and potential solutions for apparent failures to exert the mental effort required of us.

  20. A neural joint model for entity and relation extraction from biomedical text.

    PubMed

    Li, Fei; Zhang, Meishan; Fu, Guohong; Ji, Donghong

    2017-03-31

    Extracting biomedical entities and their relations from text has important applications on biomedical research. Previous work primarily utilized feature-based pipeline models to process this task. Many efforts need to be made on feature engineering when feature-based models are employed. Moreover, pipeline models may suffer error propagation and are not able to utilize the interactions between subtasks. Therefore, we propose a neural joint model to extract biomedical entities as well as their relations simultaneously, and it can alleviate the problems above. Our model was evaluated on two tasks, i.e., the task of extracting adverse drug events between drug and disease entities, and the task of extracting resident relations between bacteria and location entities. Compared with the state-of-the-art systems in these tasks, our model improved the F1 scores of the first task by 5.1% in entity recognition and 8.0% in relation extraction, and that of the second task by 9.2% in relation extraction. The proposed model achieves competitive performances with less work on feature engineering. We demonstrate that the model based on neural networks is effective for biomedical entity and relation extraction. In addition, parameter sharing is an alternative method for neural models to jointly process this task. Our work can facilitate the research on biomedical text mining.

  1. International Space Station Research for the Next Decade: International Coordination and Research Accomplishments

    NASA Technical Reports Server (NTRS)

    Thumm, Tracy L.; Robinson, Julie A.; Johnson-Green, Perry; Buckley, Nicole; Karabadzhak, George; Nakamura, Tai; Sorokin, Igor V.; Zell, Martin; Sabbagh, Jean

    2011-01-01

    During 2011, the International Space Station reached an important milestone in the completion of assembly and the shift to the focus on a full and continuous utilization mission in space. The ISS partnership itself has also met a milestone in the coordination and cooperation of utilization activities including research, technology development and education. We plan and track all ISS utilization activities jointly and have structures in place to cooperate on common goals by sharing ISS assets and resources, and extend the impacts and efficiency of utilization activities. The basic utilization areas on the ISS include research, technology development and testing, and education/outreach. Research can be categorized as applied research for future exploration, basic research taking advantage of the microgravity and open space environment, and Industrial R&D / commercial research focused at industrial product development and improvement. Technology development activities range from testing of new spacecraft systems and materials to the use of ISS as an analogue for future exploration missions to destinations beyond Earth orbit. This presentation, made jointly by all ISS international partners, will highlight the ways that international cooperation in all of these areas is achieved, and the overall accomplishments that have come as well as future perspectives from the cooperation. Recently, the partnership has made special efforts to increase the coordination and impact of ISS utilization that has humanitarian benefits. In this context the paper will highlight tentative ISS utilization developments in the areas of Earth remote sensing, medical technology transfer, and education/outreach.

  2. Intellectual Disability Policy as Developed, Expressed, and Evaluated in AAIDD/The Arc Joint Statements: The Role of Organization Position Statements.

    PubMed

    Luckasson, Ruth; Ford, Marty E; McMillan, Elise D; Misilo, Frederick M; Nygren, Margaret A

    2017-07-01

    The American Association on Intellectual and Developmental Disabilities (AAIDD) and The Arc of the United States (The Arc) have a long history of joined efforts to develop, express, and evaluate disability policies. These efforts have resulted in a series of formal statements on critical issues such as education, healthcare, human rights, and criminal justice. Their joint efforts further important policy goals including providing clear strong communication about important policy values and directions, promulgating key principles of high quality supports and services, affirming best professional practices, and emphasizing personal outcomes. In addition, the joint efforts (a) affirm important aspects of organization identity; (b) enhance the organizations' abilities to assure the input of a wide variety of perspectives; (c) engage members' expanded ranges of experiences and talents; (d) multiply staff and leadership resources; (e) increase communication strength and avenues; and (f) establish processes for timely review and revision of policies as critical disability issues arise or change, and new opportunities for policy integration and advancement occur. This article describes the processes used to develop, express, and evaluate the position statements; summarizes the policy content of several joint statements; and discusses the role of these organization position statements.

  3. Global unbalance in seaweed production, research effort and biotechnology markets.

    PubMed

    Mazarrasa, Inés; Olsen, Ylva S; Mayol, Eva; Marbà, Núria; Duarte, Carlos M

    2014-01-01

    Exploitation of the world's oceans is rapidly growing as evidenced by a booming patent market of marine products including seaweed, a resource that is easily accessible without sophisticated bioprospecting technology and that has a high level of domestication globally. The investment in research effort on seaweed aquaculture has recently been identified to be the main force for the development of a biotechnology market of seaweed-derived products and is a more important driver than the capacity of seaweed production. Here, we examined seaweed patent registrations between 1980 and 2009 to assess the growth rate of seaweed biotechnology, its geographic distribution and the types of applications patented. We compare this growth with scientific investment in seaweed aquaculture and with the market of seaweed production. We found that both the seaweed patenting market and the rate of scientific publications are rapidly growing (11% and 16.8% per year respectively) since 1990. The patent market is highly geographically skewed (95% of all registrations belonging to ten countries and the top two holding 65% of the total) compared to the distribution of scientific output among countries (60% of all scientific publications belonging to ten countries and the top two countries holding a 21%), but more homogeneously distributed than the production market (with a 99.8% belonging to the top ten countries, and a 71% to the top two). Food industry was the dominant application for both the patent registrations (37.7%) and the scientific publications (21%) followed in both cases by agriculture and aquaculture applications. This result is consistent with the seaweed taxa most represented. Kelp, which was the target taxa for 47% of the patent registrations, is a traditional ingredient in Asian food and Gracilaria and Ulva, which were the focus of 15% and 13% of the scientific publications respectively, that are also used in more sophisticated applications such as cosmetics, chemical

  4. The Effort Paradox: Effort Is Both Costly and Valued.

    PubMed

    Inzlicht, Michael; Shenhav, Amitai; Olivola, Christopher Y

    2018-04-01

    According to prominent models in cognitive psychology, neuroscience, and economics, effort (be it physical or mental) is costly: when given a choice, humans and non-human animals alike tend to avoid effort. Here, we suggest that the opposite is also true and review extensive evidence that effort can also add value. Not only can the same outcomes be more rewarding if we apply more (not less) effort, sometimes we select options precisely because they require effort. Given the increasing recognition of effort's role in motivation, cognitive control, and value-based decision-making, considering this neglected side of effort will not only improve formal computational models, but also provide clues about how to promote sustained mental effort across time. Copyright © 2018 Elsevier Ltd. All rights reserved.

  5. Early rheumatoid disease. II. Patterns of joint involvement.

    PubMed Central

    Fleming, A; Benn, R T; Corbett, M; Wood, P H

    1976-01-01

    Data from the first research clinic visit (Fleming and others, 1976) have been subjected to factor analysis to identify early patterns of joint involvement. Nine patterns emerged. Two patterns, if present early, were found to have prognostic significance. An eventually more severe disease was associated with a pattern of large joint involvement (shoulder, elbow, wrist, knee) and a pattern based on metatarsophalangeal joints I and III. PMID:970995

  6. Joint Center for Artificial Photosynthesis (JCAP): DOE's Solar Fuels Energy Innovation Hub (2011 EFRC Summit)

    ScienceCinema

    Lewis, Nate

    2018-02-16

    The Joint Center for Artificial Photosynthesis (JCAP) is a DOE Energy Innovation Hub focused on fuels from sunlight. JCAP's Director, Nate Lewis, spoke at the 2011 EFRC Summit about what JCAP is and how it is partnering with the EFRC community to accelerate the progress towards new solar fuels. The 2011 EFRC Summit and Forum brought together the EFRC community and science and policy leaders from universities, national laboratories, industry and government to discuss "Science for our Nation's Energy Future." In August 2009, the Office of Science established 46 Energy Frontier Research Centers. The EFRCs are collaborative research efforts intended to accelerate high-risk, high-reward fundamental research, the scientific basis for transformative energy technologies of the future. These Centers involve universities, national laboratories, nonprofit organizations, and for-profit firms, singly or in partnerships, selected by scientific peer review. They are funded at $2 to $5 million per year for a total planned DOE commitment of $777 million over the initial five-year award period, pending Congressional appropriations. These integrated, multi-investigator Centers are conducting fundamental research focusing on one or more of several “grand challenges” and use-inspired “basic research needs” recently identified in major strategic planning efforts by the scientific community. The purpose of the EFRCs is to integrate the talents and expertise of leading scientists in a setting designed to accelerate research that transforms the future of energy and the environment.

  7. 2011 Joint Science Education Project: Research Experience in Polar Science

    NASA Astrophysics Data System (ADS)

    Wilkening, J.; Ader, V.

    2011-12-01

    The Joint Science Education Project (JSEP), sponsored by the National Science Foundation, is a two-part program that brings together students and teachers from the United States, Greenland, and Denmark, for a unique cross-cultural, first-hand experience of the realities of polar science field research in Greenland. During JSEP, students experienced research being conducted on and near the Greenland ice sheet by attending researcher presentations, visiting NSF-funded field sites (including Summit and NEEM field stations, both located on the Greenland ice sheet), and designing and conducting research projects in international teams. The results of two of these projects will be highlighted. The atmospheric project investigated the differences in CO2, UVA, UVB, temperature, and albedo in different Arctic microenvironments, while also examining the interaction between the atmosphere and water present in the given environments. It was found that the carbon dioxide levels varied: glacial environments having the lowest levels, with an average concentration of 272.500 ppm, and non-vegetated, terrestrial environments having the highest, with an average concentration of 395.143 ppm. Following up on these results, it is planned to further investigate the interaction of the water and atmosphere, including water's role in the uptake of carbon dioxide. The ecology project investigated the occurrence of unusual large blooms of Nostoc cyanobacteria in Kangerlussuaq area lakes. The water chemistry of the lakes which contained the cyanobacteria and the lakes that did not were compared. The only noticeable difference was of the lakes' acidity, lakes containing the blooms had an average pH value of 8.58, whereas lakes without the blooms had an average pH value of 6.60. Further investigation of these results is needed to determine whether or not this was a cause or effect of the cyanobacteria blooms. As a next step, it is planned to attempt to grow the blooms to monitor their effects on

  8. Mechanical instability destabilises the ankle joint directly in the ankle-sprain mechanism.

    PubMed

    Gehring, Dominic; Faschian, Katrin; Lauber, Benedikt; Lohrer, Heinz; Nauck, Tanja; Gollhofer, Albert

    2014-03-01

    Despite massive research efforts, it remains unclear how mechanical ankle instability (MAI) and functional ankle instability (FAI) affect joint control in the situation of ankle sprain. Thus, the purpose of this study was to evaluate whether individuals with MAI have deficits in stabilising their ankle joint in a close-to-injury situation compared with those with FAI and healthy controls. Ankle-joint control was assessed by means of three-dimensional motion analysis and electromyography in participants with FAI and MAI (n=19), in participants with pure FAI (n=9) and in healthy controls (n=18). Close-to-injury situations were simulated during standing, walking and jumping by means of a custom-made tilt platform. Individuals with FAI and MAI displayed significantly greater maximum ankle inversion angles (+5°) and inversion velocities (+50°/s) in the walking and jumping conditions compared to those with pure FAI and controls. Furthermore, individuals in the FAI and MAI group showed a significantly decreased pre-activation of the peroneus longus muscle during jumping compared to those with FAI. No differences between groups were found for plantar flexion and internal rotation, or for muscle activities following tilting of the platform. The present study demonstrates that MAI is characterised by impairments of ankle-joint control in close-to-injury situations. This could make these individuals more prone to recurrent ankle sprains, and suggests the need for additional mechanical support such as braces or even surgery. In addition, the study highlights the fact that dynamic experimental test conditions in the acting participant are needed to further unravel the mystery of chronic ankle instability.

  9. A Tool to Assess and Compare Knowledge Mobilization Efforts of Faculties of Education, Research Brokering Organizations, Ministries of Education, and School Districts

    ERIC Educational Resources Information Center

    Cooper, Amanda

    2015-01-01

    There are few tools that exist to measure knowledge mobilization (KMb), the process of connecting research to policy and practice across diverse organizations and sectors. This article reports on a comparison of KMb efforts of 105 educational organizations: faculties of education (N = 21), research brokering organizations (N = 44), school…

  10. Interim guide for optimum joint performance of concrete pavements.

    DOT National Transportation Integrated Search

    2011-09-01

    The purpose of this guide is to help practitioners understand how to optimize concrete pavement joint performance through the identification, mitigation, and prevention of joint deterioration. It summarizes current knowledge from research and practic...

  11. Cassini launch contingency effort

    NASA Astrophysics Data System (ADS)

    Chang, Yale; O'Neil, John M.; McGrath, Brian E.; Heyler, Gene A.; Brenza, Pete T.

    2002-01-01

    On 15 October 1997 at 4:43 AM EDT, the Cassini spacecraft was successfully launched on a Titan IVB/Centaur on a mission to explore the Saturnian system. It carried three Radioisotope Thermoelectric Generators (RTGs) and 117 Light Weight Radioisotope Heater Units (LWRHUs). As part of the joint National Aeronautics and Space Administration (NASA)/U.S. Department of Energy (DoE) safety effort, a contingency plan was prepared to address the unlikely events of an accidental suborbital reentry or out-of-orbital reentry. The objective of the plan was to develop procedures to predict, within hours, the Earth impact footprints (EIFs) for the nuclear heat sources released during the atmospheric reentry. The footprint predictions would be used in subsequent notification and recovery efforts. As part of a multi-agency team, The Johns Hopkins University Applied Physics Laboratory (JHU/APL) had the responsibility to predict the EIFs of the heat sources after a reentry, given the heat sources' release conditions from the main spacecraft. (No ablation burn-through of the heat sources' aeroshells was expected, as a result of earlier testing.) JHU/APL's other role was to predict the time of reentry from a potential orbital decay. The tools used were a three degree-of-freedom trajectory code, a database of aerodynamic coefficients for the heat sources, secure links to obtain tracking data, and a high fidelity special perturbation orbit integrator code to predict time of spacecraft reentry from orbital decay. In the weeks and days prior to launch, all the codes and procedures were exercised. Notional EIFs were derived from hypothetical reentry conditions. EIFs predicted by JHU/APL were compared to those by JPL and US SPACECOM, and were found to be in good agreement. The reentry time from orbital decay for a booster rocket for the Russian Progress M-36 freighter, a cargo ship for the Mir space station, was predicted to within 5 minutes more than two hours before reentry. For the

  12. Russian Tu-144LL SST Roll-Out for Joint NASA Research Program

    NASA Technical Reports Server (NTRS)

    1996-01-01

    The modified Tu-144LL supersonic flying laboratory is rolled out of its hangar at the Zhukovsky Air Development Center near Moscow, Russia in March 1996 at the beginning of a joint U.S. - Russian high-speed flight research program. The 'LL' stands for Letayuschaya Laboratoriya, which means Flying Laboratory. NASA teamed with American and Russian aerospace industries for an extended period in a joint international research program featuring the Russian-built Tu-144LL supersonic aircraft. The object of the program was to develop technologies for a proposed future second-generation supersonic airliner to be developed in the 21st Century. The aircraft's initial flight phase began in June 1996 and concluded in February 1998 after 19 research flights. A shorter follow-on program involving seven flights began in September 1998 and concluded in April 1999. All flights were conducted in Russia from Tupolev's facility at the Zhukovsky Air Development Center near Moscow. The centerpiece of the research program was the Tu 144LL, a first-generation Russian supersonic jetliner that was modified by its developer/builder, Tupolev ANTK (aviatsionnyy nauchno-tekhnicheskiy kompleks-roughly, aviation technical complex), into a flying laboratory for supersonic research. Using the Tu-144LL to conduct flight research experiments, researchers compared full-scale supersonic aircraft flight data with results from models in wind tunnels, computer-aided techniques, and other flight tests. The experiments provided unique aerodynamic, structures, acoustics, and operating environment data on supersonic passenger aircraft. Data collected from the research program was being used to develop the technology base for a proposed future American-built supersonic jetliner. Although actual development of such an advanced supersonic transport (SST) is currently on hold, commercial aviation experts estimate that a market for up to 500 such aircraft could develop by the third decade of the 21st Century. The

  13. From intricate to integrated: Biofabrication of articulating joints.

    PubMed

    Groen, Wilhelmina Margaretha; Diloksumpan, Paweena; van Weeren, Paul René; Levato, Riccardo; Malda, Jos

    2017-10-01

    Articulating joints owe their function to the specialized architecture and the complex interplay between multiple tissues including cartilage, bone and synovium. Especially the cartilage component has limited self-healing capacity and damage often leads to the onset of osteoarthritis, eventually resulting in failure of the joint as an organ. Although in its infancy, biofabrication has emerged as a promising technology to reproduce the intricate organization of the joint, thus enabling the introduction of novel surgical treatments, regenerative therapies, and new sets of tools to enhance our understanding of joint physiology and pathology. Herein, we address the current challenges to recapitulate the complexity of articulating joints and how biofabrication could overcome them. The combination of multiple materials, biological cues and cells in a layer-by-layer fashion, can assist in reproducing both the zonal organization of cartilage and the gradual transition from resilient cartilage toward the subchondral bone in biofabricated osteochondral grafts. In this way, optimal integration of engineered constructs with the natural surrounding tissues can be obtained. Mechanical characteristics, including the smoothness and low friction that are hallmarks of the articular surface, can be tuned with multi-head or hybrid printers by controlling the spatial patterning of printed structures. Moreover, biofabrication can use digital medical images as blueprints for printing patient-specific implants. Finally, the current rapid advances in biofabrication hold significant potential for developing joint-on-a-chip models for personalized medicine and drug testing or even for the creation of implants that may be used to treat larger parts of the articulating joint. © 2017 The Authors. Journal of Orthopaedic Research Published by Wiley Periodicals, Inc. on behalf of the Orthopaedic Research Society. J Orthop Res 35:2089-2097, 2017. © 2017 The Authors. Journal of Orthopaedic

  14. Solid Earth and Natural Hazards (SENH) Research and Applications Program and Internation

    NASA Technical Reports Server (NTRS)

    2001-01-01

    This is a final report for grant NAG5-8627 entitled 'Joint UNAVCO and JPL proposal to NASA for support of the Solid Earth and Natural Hazards Research and Applications Program and Internation'. This report consists of the following sections: (1) new installations (with site visits); (2) upgrades (with site visits; (3) upcoming upgrades (with site visits); and (4) data management and archive efforts during the performance period.

  15. US/German Collaboration in Salt Repository Research, Design and Operation - 13243

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Steininger, Walter; Hansen, Frank; Biurrun, Enrique

    2013-07-01

    Recent developments in the US and Germany [1-3] have precipitated renewed efforts in salt repository investigations and related studies. Both the German rock salt repository activities and the US waste management programs currently face challenges that may adversely affect their respective current and future state-of-the-art core capabilities in rock salt repository science and technology. The research agenda being pursued by our respective countries leverages collective efforts for the benefit of both programs. The topics addressed by the US/German salt repository collaborations align well with the findings and recommendations summarized in the January 2012 US Blue Ribbon Commission on America's Nuclearmore » Future (BRC) report [4] and are consistent with the aspirations of the key topics of the Strategic Research Agenda of the Implementing Geological Disposal of Radioactive Waste Technology Platform (IGD-TP) [5]. Against this background, a revival of joint efforts in salt repository investigations after some years of hibernation has been undertaken to leverage collective efforts in salt repository research, design, operations, and related issues for the benefit of respective programs and to form a basis for providing an attractive, cost-effective insurance against the premature loss of virtually irreplaceable scientific expertise and institutional memory. (authors)« less

  16. The Joint Aerosol-Monsoon Experiment: A New Challenge to Monsoon Climate Research

    NASA Technical Reports Server (NTRS)

    Lau, William K. M.

    2008-01-01

    Aerosol and monsoon related droughts and floods are two of the most serious environmental hazards confronting more than 60% of the population of the world living in the Asian monsoon countries. In recent years, thanks to improved satellite and in-situ observations, and better models, great strides have been made in aerosol, and monsoon research respectively. There is now a growing body of evidence suggesting that interaction of aerosol forcing with water cycle dynamics in monsoon regions may substantially alter the redistribution of energy at the earth surface and in the atmosphere, and therefore significantly impact monsoon rainfall variability and long term trends. In this talk, I will describe issues related to societal needs, scientific background, and challenges in studies of aerosol-water cycle interaction in Asian monsoon regions. As a first step towards addressing these issues, the authors call for an integrated observation and modeling research approach aimed at the interactions between aerosol chemistry and radiative effects and monsoon dynamics of the coupled ocean-atmosphere-land system. A Joint Aerosol-Monsoon Experiment (JAMEX) is proposed for 2007-2011, with an enhanced observation period during 2008-09, encompassing diverse arrays of observations from surface, aircraft, unmanned aerial vehicles, and satellites of physical and chemical properties of aerosols, long range aerosol transport as well as meteorological and oceanographic parameters in the Indo-Pacific Asian monsoon region. JAMEX will leverage on coordination among many ongoing and planned national programs on aerosols and monsoon research in China, India, Japan, Nepal, Italy, US, as well as international research programs of the World Climate Research Program (WCRP) and the World Meteorological Organization (WMO).

  17. Full-depth repair of jointed PCC pavements cast-in-place and precast procedures.

    DOT National Transportation Integrated Search

    1976-01-01

    The deterioration of jointed portland cement concrete (PCC) pavements on the interstate system in Virginia has created a need for full-depth and partial-depth repairs. In this report, efforts related to full-depth repairs are described and discussed,...

  18. Overview of NASA GRC's Efforts In SWBLI

    NASA Technical Reports Server (NTRS)

    Long-Davis, Mary Jo

    2017-01-01

    Overview of NASA Efforts (related to SWBLI research) An overview of NASA's restructured ARMD Program and the resulting new projects. Areas of research pertaining to shock wave boundary layer interaction are highlighted. Plans and status for specific tasks are presented.

  19. On Achieving Transdisciplinary Outcomes from Synergistic Research Efforts in the Northern Gulf of Mexico

    NASA Astrophysics Data System (ADS)

    Hagen, S. C.

    2017-12-01

    Multiple federal initiatives aim to evaluate and enhance sustainability and resilience at the coastal-land margin. Progressive efforts undertaken in the northern Gulf of Mexico for more than ten years have resulted in synergistic research with multiple means of federal support. Major grants include the FEMA Flood Insurance Studies, the NOAA / NOS Ecological Effects of Sea Level Rise Program, as well as the NSF Coastal SEES Program. Through a careful development of a collective enterprise the results from these and other individual programs (e.g., NOAA Sea Grant College, DHS Center of Excellence, NSF Rapid Response) have been elevated to achieve transdisciplinary outcomes. A direct product of the synergy is a system of systems approach to bio-geophysical science with the inclusion of socioeconomic processes.

  20. The Standard Joint Unit.

    PubMed

    Casajuana Kögel, Cristina; Balcells-Olivero, María Mercedes; López-Pelayo, Hugo; Miquel, Laia; Teixidó, Lídia; Colom, Joan; Nutt, David John; Rehm, Jürgen; Gual, Antoni

    2017-07-01

    Reliable data on cannabis quantities is required to improve assessment of cannabis consumption for epidemiological analysis and clinical assessment, consequently a Standard Joint Unit (SJU) based on quantity of 9-Tetrahydrocannabinol (9-THC) has been established. Naturalistic study of a convenience sample recruited from February 2015-June 2016 in universities, leisure spaces, mental health services and cannabis clubs in Barcelona. Adults, reporting cannabis use in the last 60 days, without cognitive impairment or language barriers, answered a questionnaire on cannabis use and were asked to donate a joint to further determine their 9-THC and Cannabidiol (CBD) content. 492 participants donated 315 valid joints. Donators were on average 29 years old, mostly men (77%), single (75%), with at least secondary studies (73%) and in active employment (63%). Marijuana joints (N=232) contained a median of 6.56mg of 9-THC (Interquartile range-IQR=10,22) and 0.02mg of CBD (IQR=0.02); hashish joints (N=83) a median of 7.94mg of 9-THC (IQR=10,61) and 3.24mg of CBD (IQR=3.21). Participants rolled 4 joints per gram of cannabis and paid 5€ per gram (median values). Consistent 9-THC-content in joints lead to a SJU of 7mg of 9-THC, the integer number closest to the median values shared by both cannabis types. Independently if marijuana or hashish, 1 SJU = 1 joint = 0.25 g of cannabis = 7 mg of 9-THC. For CBD, only hashish SJU contained relevant levels. Similarly to the Standard Drink Unit for alcohol, the SJU is useful for clinical, epidemiological and research purposes. Copyright © 2017 Elsevier B.V. All rights reserved.

  1. Leopard (Panthera pardus) status, distribution, and the research efforts across its range.

    PubMed

    Jacobson, Andrew P; Gerngross, Peter; Lemeris, Joseph R; Schoonover, Rebecca F; Anco, Corey; Breitenmoser-Würsten, Christine; Durant, Sarah M; Farhadinia, Mohammad S; Henschel, Philipp; Kamler, Jan F; Laguardia, Alice; Rostro-García, Susana; Stein, Andrew B; Dollar, Luke

    2016-01-01

    The leopard's (Panthera pardus) broad geographic range, remarkable adaptability, and secretive nature have contributed to a misconception that this species might not be severely threatened across its range. We find that not only are several subspecies and regional populations critically endangered but also the overall range loss is greater than the average for terrestrial large carnivores. To assess the leopard's status, we compile 6,000 records at 2,500 locations from over 1,300 sources on its historic (post 1750) and current distribution. We map the species across Africa and Asia, delineating areas where the species is confirmed present, is possibly present, is possibly extinct or is almost certainly extinct. The leopard now occupies 25-37% of its historic range, but this obscures important differences between subspecies. Of the nine recognized subspecies, three (P. p. pardus, fusca, and saxicolor) account for 97% of the leopard's extant range while another three (P. p. orientalis, nimr, and japonensis) have each lost as much as 98% of their historic range. Isolation, small patch sizes, and few remaining patches further threaten the six subspecies that each have less than 100,000 km(2) of extant range. Approximately 17% of extant leopard range is protected, although some endangered subspecies have far less. We found that while leopard research was increasing, research effort was primarily on the subspecies with the most remaining range whereas subspecies that are most in need of urgent attention were neglected.

  2. Leopard (Panthera pardus) status, distribution, and the research efforts across its range

    PubMed Central

    Gerngross, Peter; Lemeris Jr., Joseph R.; Schoonover, Rebecca F.; Anco, Corey; Breitenmoser-Würsten, Christine; Durant, Sarah M.; Farhadinia, Mohammad S.; Henschel, Philipp; Kamler, Jan F.; Laguardia, Alice; Rostro-García, Susana; Stein, Andrew B.; Dollar, Luke

    2016-01-01

    The leopard’s (Panthera pardus) broad geographic range, remarkable adaptability, and secretive nature have contributed to a misconception that this species might not be severely threatened across its range. We find that not only are several subspecies and regional populations critically endangered but also the overall range loss is greater than the average for terrestrial large carnivores. To assess the leopard’s status, we compile 6,000 records at 2,500 locations from over 1,300 sources on its historic (post 1750) and current distribution. We map the species across Africa and Asia, delineating areas where the species is confirmed present, is possibly present, is possibly extinct or is almost certainly extinct. The leopard now occupies 25–37% of its historic range, but this obscures important differences between subspecies. Of the nine recognized subspecies, three (P. p. pardus, fusca, and saxicolor) account for 97% of the leopard’s extant range while another three (P. p. orientalis, nimr, and japonensis) have each lost as much as 98% of their historic range. Isolation, small patch sizes, and few remaining patches further threaten the six subspecies that each have less than 100,000 km2 of extant range. Approximately 17% of extant leopard range is protected, although some endangered subspecies have far less. We found that while leopard research was increasing, research effort was primarily on the subspecies with the most remaining range whereas subspecies that are most in need of urgent attention were neglected. PMID:27168983

  3. Force Structure. Joint Seabasing Would Benefit from a Comprehensive Management Approach and Rigorous Experimentation before Services Spend Billions on New Capabilities

    DTIC Science & Technology

    2007-01-01

    results could be compromised. While service development efforts tied to seabasing are approaching milestones for investment decisions , it is...estimates for joint seabasing options are developed and made transparent to DOD and Congress, decision makers will not be able to evaluate the cost...Integrate Service Initiatives 10 DOD Has Not Developed a Joint Experimentation Campaign Plan to Inform Decisions About Joint Seabasing 16 Timeframe for

  4. IJEMS: Iowa Joint Experiment in Microgravity Solidification

    NASA Technical Reports Server (NTRS)

    Bendle, John R.; Mashl, Steven J.; Hardin, Richard A.

    1995-01-01

    The Iowa Joint Experiment in Microgravity Solidification (IJEMS) is a cooperative effort between Iowa State University and the University of Iowa to study the formation of metal-matrix composites in a microgravity environment. Of particular interest is the interaction between the solid/liquid interface and the particles in suspension. The experiment is scheduled to fly on STS-69, Space Shuttle Endeavor on August 3, 1995. This project is unique in its heavy student participation and cooperation between the universities involved.

  5. Damage detection of an in-service condensation pipeline joint

    NASA Astrophysics Data System (ADS)

    Briand, Julie; Rezaei, Davood; Taheri, Farid

    2010-04-01

    The early detection of damage in structural or mechanical systems is of vital importance. With early detection, the damage may be repaired before the integrity of the system is jeopardized, resulting in monetary losses, loss of life or limb, and environmental impacts. Among the various types of structural health monitoring techniques, vibration-based methods are of significant interest since the damage location does not need to be known beforehand, making it a more versatile approach. The non-destructive damage detection method used for the experiments herein is a novel vibration-based method which uses an index called the EMD Energy Damage Index, developed with the aim of providing improved qualitative results compared to those methods currently available. As part of an effort to establish the integrity and limitation of this novel damage detection method, field testing was completed on a mechanical pipe joint on a condensation line, located in the physical plant of Dalhousie University. Piezoceramic sensors, placed at various locations around the joint were used to monitor the free vibration of the pipe imposed through the use of an impulse hammer. Multiple damage progression scenarios were completed, each having a healthy state and multiple damage cases. Subsequently, the recorded signals from the healthy and damaged joint were processed through the EMD Energy Damage Index developed in-house in an effort to detect the inflicted damage. The proposed methodology successfully detected the inflicted damages. In this paper, the effects of impact location, sensor location, frequency bandwidth, intrinsic mode functions, and boundary conditions are discussed.

  6. Lamb wave propagation in a restricted geometry composite pi-joint specimen

    NASA Astrophysics Data System (ADS)

    Blackshire, James L.; Soni, Som

    2012-05-01

    The propagation of elastic waves in a material can involve a number of complex physical phenomena, resulting in both subtle and dramatic effects on detected signal content. In recent years, the use of advanced methods for characterizing and imaging elastic wave propagation and scattering processes has increased, where for example the use of scanning laser vibrometry and advanced computational models have been used very effectively to identify propagating modes, scattering phenomena, and damage feature interactions. In the present effort, the propagation of Lamb waves within a narrow, constrained geometry composite pi-joint structure are studied using 3D finite element models and scanning laser vibrometry measurements, where the effects of varying sample thickness, complex joint curvatures, and restricted structure geometries are highlighted, and a direct comparison of computational and experimental results are provided for simulated and realistic geometry composite pi-joint samples.

  7. Joint BioEnergy Institute

    ScienceCinema

    Keasling, Jay; Simmons, Blake; Tartaglino, Virginia; Baidoo, Edward; Kothari, Ankita

    2018-05-11

    The Joint BioEnergy Institute (JBEI) is a U.S. Department of Energy (DOE) Bioenergy Research Center dedicated to developing advanced biofuels—liquid fuels derived from the solar energy stored in plant biomass that can replace gasoline, diesel and jet fuels.

  8. Failure of dissimilar material bonded joints

    NASA Astrophysics Data System (ADS)

    Konstantakopoulou, M.; Deligianni, A.; Kotsikos, G.

    2016-03-01

    Joining of materials in structural design has always been a challenge for engineers. Bolting and riveting has been used for many years, until the emergence of fusion welding which revolutionised construction in areas such as shipbuilding, automotive, infrastructure and consumer goods. Extensive research in the past 50 years has resulted in better understanding of the process and minimised the occurrence of failures associated with fusion welding such as, residual stress cracking, stress corrosion and corrosion fatigue cracking, localised reduction in mechanical properties due to microstructural changes (heat affected zone) etc. Bonding has been a technique that has been proposed as an alternative because it eliminates several of the problems associated with fusion welding. But, despite some applications it has not seen wide use. There is however a renewed interest in adhesively bonded joints, as designers look for ever more efficient structures which inevitably leads to the use and consequently joining of combinations of lightweight materials, often with fundamentally different mechanical and physical properties. This chapter provides a review of adhesively bonded joints and reports on improvements to bonded joint strength through the introduction of carbon nanotubes at the bond interface. Results from various workers in the field are reported as well as the findings of the authors in this area of research. It is obvious that there are several challenges that need to be addressed to further enhance the strength of bonded joints and worldwide research is currently underway to address those shortcomings and build confidence in the implementation of these new techniques.

  9. Analysis of postmarket complaints database for the iFuse SI Joint Fusion System®: a minimally invasive treatment for degenerative sacroiliitis and sacroiliac joint disruption

    PubMed Central

    Miller, Larry E; Reckling, W Carlton; Block, Jon E

    2013-01-01

    Background The sacroiliac joint is a common but under-recognized source of low back and gluteal pain. Patients with degenerative sacroiliitis or sacroiliac joint disruption resistant to nonsurgical treatments may undergo open surgery with sacroiliac joint arthrodesis, although outcomes are mixed and risks are significant. Minimally invasive sacroiliac joint arthrodesis was developed to minimize the risk of iatrogenic injury and to improve patient outcomes compared with open surgery. Methods Between April 2009 and January 2013, 5319 patients were treated with the iFuse SI Joint Fusion System® for conditions including sacroiliac joint disruption and degenerative sacroiliitis. A database was prospectively developed to record all complaints reported to the manufacturer in patients treated with the iFuse device. Complaints were collected through spontaneous reporting mechanisms in support of ongoing mandatory postmarket surveillance efforts. Results Complaints were reported in 204 (3.8%) patients treated with the iFuse system. Pain was the most commonly reported clinical complaint (n = 119, 2.2%), with nerve impingement (n = 48, 0.9%) and recurrent sacroiliac joint pain (n = 43, 0.8%) most frequently cited. All other clinical complaints were rare (≤0.2%). Ninety-six revision surgeries were performed in 94 (1.8%) patients at a median follow-up of four (range 0–30) months. Revisions were typically performed in the early postoperative period for treatment of a symptomatic malpositioned implant (n = 46, 0.9%) or to correct an improperly sized implant in an asymptomatic patient (n = 10, 0.2%). Revisions in the late postoperative period were performed to treat symptom recurrence (n = 34, 0.6%) or for continued pain of undetermined etiology (n = 6, 0.1%). Conclusion Analysis of a postmarket product complaints database demonstrates an overall low risk of complaints with the iFuse SI Joint Fusion System in patients with degenerative sacroiliitis or sacroiliac joint

  10. Analysis of postmarket complaints database for the iFuse SI Joint Fusion System®: a minimally invasive treatment for degenerative sacroiliitis and sacroiliac joint disruption.

    PubMed

    Miller, Larry E; Reckling, W Carlton; Block, Jon E

    2013-01-01

    The sacroiliac joint is a common but under-recognized source of low back and gluteal pain. Patients with degenerative sacroiliitis or sacroiliac joint disruption resistant to nonsurgical treatments may undergo open surgery with sacroiliac joint arthrodesis, although outcomes are mixed and risks are significant. Minimally invasive sacroiliac joint arthrodesis was developed to minimize the risk of iatrogenic injury and to improve patient outcomes compared with open surgery. Between April 2009 and January 2013, 5319 patients were treated with the iFuse SI Joint Fusion System® for conditions including sacroiliac joint disruption and degenerative sacroiliitis. A database was prospectively developed to record all complaints reported to the manufacturer in patients treated with the iFuse device. Complaints were collected through spontaneous reporting mechanisms in support of ongoing mandatory postmarket surveillance efforts. Complaints were reported in 204 (3.8%) patients treated with the iFuse system. Pain was the most commonly reported clinical complaint (n = 119, 2.2%), with nerve impingement (n = 48, 0.9%) and recurrent sacroiliac joint pain (n = 43, 0.8%) most frequently cited. All other clinical complaints were rare (≤0.2%). Ninety-six revision surgeries were performed in 94 (1.8%) patients at a median follow-up of four (range 0-30) months. Revisions were typically performed in the early postoperative period for treatment of a symptomatic malpositioned implant (n = 46, 0.9%) or to correct an improperly sized implant in an asymptomatic patient (n = 10, 0.2%). Revisions in the late postoperative period were performed to treat symptom recurrence (n = 34, 0.6%) or for continued pain of undetermined etiology (n = 6, 0.1%). Analysis of a postmarket product complaints database demonstrates an overall low risk of complaints with the iFuse SI Joint Fusion System in patients with degenerative sacroiliitis or sacroiliac joint disruption.

  11. Effortful Control and Academic Achievement in Rural China

    ERIC Educational Resources Information Center

    Zhang, Li; Rao, Nirmala

    2017-01-01

    Research Findings: This study investigated the relationships between effortful control and early literacy and mathematics achievement. A total of 181 children (85 girls and 96 boys) from rural China were assessed when they were in Grades 1 and 2. Path analyses controlling for maternal education indicated that effortful control at the beginning of…

  12. Dopamine does double duty in motivating cognitive effort

    PubMed Central

    Westbrook, Andrew; Braver, Todd S.

    2015-01-01

    Cognitive control is subjectively costly, suggesting that engagement is modulated in relationship to incentive state. Dopamine appears to play key roles. In particular, dopamine may mediate cognitive effort by two broad classes of functions: 1) modulating the functional parameters of working memory circuits subserving effortful cognition, and 2) mediating value-learning and decision-making about effortful cognitive action. Here we tie together these two lines of research, proposing how dopamine serves “double duty”, translating incentive information into cognitive motivation. PMID:26889810

  13. The differential diagnosis of children with joint hypermobility: a review of the literature

    PubMed Central

    Tofts, Louise J; Elliott, Elizabeth J; Munns, Craig; Pacey, Verity; Sillence, David O

    2009-01-01

    Background In this study we aimed to identify and review publications relating to the diagnosis of joint hypermobility and instability and develop an evidence based approach to the diagnosis of children presenting with joint hypermobility and related symptoms. Methods We searched Medline for papers with an emphasis on the diagnosis of joint hypermobility, including Heritable Disorders of Connective Tissue (HDCT). Results 3330 papers were identified: 1534 pertained to instability of a particular joint; 1666 related to the diagnosis of Ehlers Danlos syndromes and 330 related to joint hypermobility. There are inconsistencies in the literature on joint hypermobility and how it relates to and overlaps with milder forms of HDCT. There is no reliable method of differentiating between Joint Hypermobility Syndrome, familial articular hypermobility and Ehlers-Danlos syndrome (hypermobile type), suggesting these three disorders may be different manifestations of the same spectrum of disorders. We describe our approach to children presenting with joint hypermobility and the published evidence and expert opinion on which this is based. Conclusion There is value in identifying both the underlying genetic cause of joint hypermobility in an individual child and those hypermobile children who have symptoms such as pain and fatigue and might benefit from multidisciplinary rehabilitation management. Every effort should be made to diagnose the underlying disorder responsible for joint hypermobility which may only become apparent over time. We recommend that the term "Joint Hypermobility Syndrome" is used for children with symptomatic joint hypermobility resulting from any underlying HDCT and that these children are best described using both the term Joint Hypermobility Syndrome and their HDCT diagnosis. PMID:19123951

  14. An overview of the joint FAA/NASA aircraft/ground runway friction program

    NASA Technical Reports Server (NTRS)

    Yager, Thomas J.

    1989-01-01

    There is a need for information on runways which may become slippery due to various forms and types of contaminants. Experience has shown that since the beginning of all weather aircraft operations, there have been landing and aborted takeoff incidents and/or accidents each year where aircraft have either run off the end or veered off the shoulder of low friction runways. NASA Langley's Landing and Impact Dynamics Branch is involved in several research programs directed towards obtaining a better understanding of how different tire properties interact with varying pavement surface characteristics to produce acceptable performance for aircraft ground handling requirements. One such effort, which was jointly supported by not only NASA and the FAA but by several aviation industry groups including the Flight Safety Foundation, is described.

  15. Effort versus Ability: Preferences and Affective Reactions in Achievement Settings.

    ERIC Educational Resources Information Center

    Brown, Jonathon

    Psychological researchers continue to debate the relative contribution of ability and effort to feelings of self-worth. To investigate student preferences for ability or effort and their relationship to self-worth, and to assess the relative contribution of ability and effort to affective experience, two separate studies were undertaken. In the…

  16. Breaking the Double-Edged Sword of Effort/Trying Hard: Developmental Equilibrium and Longitudinal Relations among Effort, Achievement, and Academic Self-Concept

    ERIC Educational Resources Information Center

    Marsh, Herbert W.; Pekrun, Reinhard; Lichtenfeld, Stephanie; Guo, Jiesi; Arens, A. Katrin; Murayama, Kou

    2016-01-01

    Ever since the classic research of Nicholls (1976) and others, effort has been recognized as a double-edged sword: while it might enhance achievement, it undermines academic self-concept (ASC). However, there has not been a thorough evaluation of the longitudinal reciprocal effects of effort, ASC, and achievement, in the context of modern…

  17. 2006 Electrochemistry Gordon Research Conference - February 12-17-2006

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Abruna, Hector D.

    The Gordon Research Conference (GRC) on Electrochemistry was held at Santa Ynez Valley Marriott, Buellton California from February 12-17, 2006. The Conference was well-attended with 113 participants (attendees list attached). The attendees represented the spectrum of endeavor in this field coming from academia, industry, and government laboratories, both U.S. and foreign scientists, senior researchers, young investigators, and students. In designing the formal speakers program, emphasis was placed on current unpublished research and discussion of the future target areas in this field. There was a conscious effort to stimulate lively discussion about the key issues in the field today. Time formore » formal presentations was limited in the interest of group discussions. In order that more scientists could communicate their most recent results, poster presentation time was scheduled. Attached is a copy of the formal schedule and speaker program and the poster program. In addition to these formal interactions, "free time" was scheduled to allow informal discussions. Such discussions are fostering new collaborations and joint efforts in the field.« less

  18. ASME Code Efforts Supporting HTGRs

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    D.K. Morton

    2010-09-01

    In 1999, an international collaborative initiative for the development of advanced (Generation IV) reactors was started. The idea behind this effort was to bring nuclear energy closer to the needs of sustainability, to increase proliferation resistance, and to support concepts able to produce energy (both electricity and process heat) at competitive costs. The U.S. Department of Energy has supported this effort by pursuing the development of the Next Generation Nuclear Plant, a high temperature gas-cooled reactor. This support has included research and development of pertinent data, initial regulatory discussions, and engineering support of various codes and standards development. This reportmore » discusses the various applicable American Society of Mechanical Engineers (ASME) codes and standards that are being developed to support these high temperature gascooled reactors during construction and operation. ASME is aggressively pursuing these codes and standards to support an international effort to build the next generation of advanced reactors so that all can benefit.« less

  19. ASME Code Efforts Supporting HTGRs

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    D.K. Morton

    2011-09-01

    In 1999, an international collaborative initiative for the development of advanced (Generation IV) reactors was started. The idea behind this effort was to bring nuclear energy closer to the needs of sustainability, to increase proliferation resistance, and to support concepts able to produce energy (both electricity and process heat) at competitive costs. The U.S. Department of Energy has supported this effort by pursuing the development of the Next Generation Nuclear Plant, a high temperature gas-cooled reactor. This support has included research and development of pertinent data, initial regulatory discussions, and engineering support of various codes and standards development. This reportmore » discusses the various applicable American Society of Mechanical Engineers (ASME) codes and standards that are being developed to support these high temperature gascooled reactors during construction and operation. ASME is aggressively pursuing these codes and standards to support an international effort to build the next generation of advanced reactors so that all can benefit.« less

  20. ASME Code Efforts Supporting HTGRs

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    D.K. Morton

    2012-09-01

    In 1999, an international collaborative initiative for the development of advanced (Generation IV) reactors was started. The idea behind this effort was to bring nuclear energy closer to the needs of sustainability, to increase proliferation resistance, and to support concepts able to produce energy (both electricity and process heat) at competitive costs. The U.S. Department of Energy has supported this effort by pursuing the development of the Next Generation Nuclear Plant, a high temperature gas-cooled reactor. This support has included research and development of pertinent data, initial regulatory discussions, and engineering support of various codes and standards development. This reportmore » discusses the various applicable American Society of Mechanical Engineers (ASME) codes and standards that are being developed to support these high temperature gascooled reactors during construction and operation. ASME is aggressively pursuing these codes and standards to support an international effort to build the next generation of advanced reactors so that all can benefit.« less

  1. Dataglove measurement of joint angles in sign language handshapes

    PubMed Central

    Eccarius, Petra; Bour, Rebecca; Scheidt, Robert A.

    2012-01-01

    In sign language research, we understand little about articulatory factors involved in shaping phonemic boundaries or the amount (and articulatory nature) of acceptable phonetic variation between handshapes. To date, there exists no comprehensive analysis of handshape based on the quantitative measurement of joint angles during sign production. The purpose of our work is to develop a methodology for collecting and visualizing quantitative handshape data in an attempt to better understand how handshapes are produced at a phonetic level. In this pursuit, we seek to quantify the flexion and abduction angles of the finger joints using a commercial data glove (CyberGlove; Immersion Inc.). We present calibration procedures used to convert raw glove signals into joint angles. We then implement those procedures and evaluate their ability to accurately predict joint angle. Finally, we provide examples of how our recording techniques might inform current research questions. PMID:23997644

  2. A Euclid, LSST and WFIRST Joint Processing Study

    NASA Astrophysics Data System (ADS)

    Chary, Ranga-Ram; Joint Processing Working Group

    2018-01-01

    Euclid, LSST and WFIRST are the flagship cosmological projects of the next decade. By mapping several thousand square degrees of sky and covering the electromagnetic spectrum from the optical to the NIR with (sub-)arcsec resolution, these projects will provide exciting new constraints on the nature of dark energy and dark matter. The ultimate cosmological, astrophysical and time-domain science yield from these missions, which will detect several billions of sources, requires joint processing at the pixel-level. Three U.S. agencies (DOE, NASA and NSF) are supporting an 18-month study which aims to 1) assess the optimal techniques to combine these, and ancillary data sets at the pixel level; 2) investigate options for an interface that will enable community access to the joint data products; and 3) identify the computing and networking infrastructure to properly handle and manipulate these large datasets together. A Joint Processing Working Group (JPWG) is carrying out this study and consists of US-based members from the community and science/data processing centers of each of these projects. Coordination with European partners is envisioned in the future and European Euclid members are involved in the JPWG as observers. The JPWG will scope the effort and resources required to build up the capabilities to support scientific investigations using joint processing in time for the start of science surveys by LSST and Euclid.

  3. Public key infrastructure for DOE security research

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Aiken, R.; Foster, I.; Johnston, W.E.

    This document summarizes the Department of Energy`s Second Joint Energy Research/Defence Programs Security Research Workshop. The workshop, built on the results of the first Joint Workshop which reviewed security requirements represented in a range of mission-critical ER and DP applications, discussed commonalties and differences in ER/DP requirements and approaches, and identified an integrated common set of security research priorities. One significant conclusion of the first workshop was that progress in a broad spectrum of DOE-relevant security problems and applications could best be addressed through public-key cryptography based systems, and therefore depended upon the existence of a robust, broadly deployed public-keymore » infrastructure. Hence, public-key infrastructure ({open_quotes}PKI{close_quotes}) was adopted as a primary focus for the second workshop. The Second Joint Workshop covered a range of DOE security research and deployment efforts, as well as summaries of the state of the art in various areas relating to public-key technologies. Key findings were that a broad range of DOE applications can benefit from security architectures and technologies built on a robust, flexible, widely deployed public-key infrastructure; that there exists a collection of specific requirements for missing or undeveloped PKI functionality, together with a preliminary assessment of how these requirements can be met; that, while commercial developments can be expected to provide many relevant security technologies, there are important capabilities that commercial developments will not address, due to the unique scale, performance, diversity, distributed nature, and sensitivity of DOE applications; that DOE should encourage and support research activities intended to increase understanding of security technology requirements, and to develop critical components not forthcoming from other sources in a timely manner.« less

  4. Characteristics of clinical shoulder research over the last decade: a review of shoulder articles in The Journal of Bone & Joint Surgery from 2004 to 2014.

    PubMed

    Gartsman, Gary M; Morris, Brent J; Unger, R Zackary; Laughlin, Mitzi S; Elkousy, Hussein A; Edwards, T Bradley

    2015-03-04

    The purpose of this study was to determine characteristics and trends in published shoulder research over the last decade in a leading orthopaedic journal. We examined all clinical shoulder articles published in The Journal of Bone & Joint Surgery from 2004 to 2014. The number of citations, authorship, academic degrees of the authors, country and institution of origin, topic, level of evidence, positive or nonpositive outcome, and inclusion of validated patient-reported outcome measures were assessed for each article. Shoulder articles that included an author with an advanced research degree (MD [Doctor of Medicine] with a PhD [Doctor of Philosophy] or other advanced degree) increased during the study period (p = 0.047). Level-I, II, and III studies were more likely to have an author with an advanced research degree, and Level-IV studies were more likely to have MDs only (p = 0.03). Overall, there was great variability of outcome measures, with at least thirty-nine different validated or nonvalidated outcome measures reported. Over the last decade, there was an improvement in the level of evidence of shoulder articles published in The Journal of Bone & Joint Surgery that corresponds with recent emphasis on evidence-based medicine. A consensus is needed in shoulder research for more consistent application of validated patient-reported outcome measurement tools. Copyright © 2015 by The Journal of Bone and Joint Surgery, Incorporated.

  5. Exploring the IMF of star clusters: a joint SLUG and LEGUS effort

    NASA Astrophysics Data System (ADS)

    Ashworth, G.; Fumagalli, M.; Krumholz, M. R.; Adamo, A.; Calzetti, D.; Chandar, R.; Cignoni, M.; Dale, D.; Elmegreen, B. G.; Gallagher, J. S., III; Gouliermis, D. A.; Grasha, K.; Grebel, E. K.; Johnson, K. E.; Lee, J.; Tosi, M.; Wofford, A.

    2017-08-01

    We present the implementation of a Bayesian formalism within the Stochastically Lighting Up Galaxies (slug) stellar population synthesis code, which is designed to investigate variations in the initial mass function (IMF) of star clusters. By comparing observed cluster photometry to large libraries of clusters simulated with a continuously varying IMF, our formalism yields the posterior probability distribution function (PDF) of the cluster mass, age and extinction, jointly with the parameters describing the IMF. We apply this formalism to a sample of star clusters from the nearby galaxy NGC 628, for which broad-band photometry in five filters is available as part of the Legacy ExtraGalactic UV Survey (LEGUS). After allowing the upper-end slope of the IMF (α3) to vary, we recover PDFs for the mass, age and extinction that are broadly consistent with what is found when assuming an invariant Kroupa IMF. However, the posterior PDF for α3 is very broad due to a strong degeneracy with the cluster mass, and it is found to be sensitive to the choice of priors, particularly on the cluster mass. We find only a modest improvement in the constraining power of α3 when adding Hα photometry from the companion Hα-LEGUS survey. Conversely, Hα photometry significantly improves the age determination, reducing the frequency of multi-modal PDFs. With the aid of mock clusters, we quantify the degeneracy between physical parameters, showing how constraints on the cluster mass that are independent of photometry can be used to pin down the IMF properties of star clusters.

  6. Learning Disabilities: Implications for Policy regarding Research and Practice--A Report by the National Joint Committee on Learning Disabilities, March 2011

    ERIC Educational Resources Information Center

    Learning Disabilities: A Multidisciplinary Journal, 2012

    2012-01-01

    The National Joint Committee on Learning Disabilities (NJCLD) affirms that the construct of learning disabilities represents a valid, unique, and heterogeneous group of disorders, and that recognition of this construct is essential for sound policy and practice. An extensive body of scientific research on learning disabilities continues to support…

  7. Joint Science Education Project: Learning about polar science in Greenland

    NASA Astrophysics Data System (ADS)

    Foshee Reed, Lynn

    2014-05-01

    The Joint Science Education Project (JSEP) is a successful summer science and culture opportunity in which students and teachers from the United States, Denmark, and Greenland come together to learn about the research conducted in Greenland and the logistics involved in supporting the research. They conduct experiments first-hand and participate in inquiry-based educational activities alongside scientists and graduate students at a variety of locations in and around Kangerlussuaq, Greenland, and on the top of the ice sheet at Summit Station. The Joint Committee, a high-level forum involving the Greenlandic, Danish and U.S. governments, established the Joint Science Education Project in 2007, as a collaborative diplomatic effort during the International Polar Year to: • Educate and inspire the next generation of polar scientists; • Build strong networks of students and teachers among the three countries; and • Provide an opportunity to practice language and communication skills Since its inception, JSEP has had 82 student and 22 teacher participants and has involved numerous scientists and field researchers. The JSEP format has evolved over the years into its current state, which consists of two field-based subprograms on site in Greenland: the Greenland-led Kangerlussuaq Science Field School and the U.S.-led Arctic Science Education Week. All travel, transportation, accommodations, and meals are provided to the participants at no cost. During the 2013 Kangerlussuaq Science Field School, students and teachers gathered data in a biodiversity study, created and set geo- and EarthCaches, calculated glacial discharge at a melt-water stream and river, examined microbes and tested for chemical differences in a variety of lakes, measured ablation at the edge of the Greenland Ice Sheet, and learned about fossils, plants, animals, minerals and rocks of Greenland. In addition, the students planned and led cultural nights, sharing food, games, stories, and traditions of

  8. SERVIR Support to NSDI Efforts in Mesoamerica, Africa and the Himalayas

    NASA Technical Reports Server (NTRS)

    Delgado, Francisco

    2014-01-01

    SERVIR is a joint effort between NASA, USAID to build or improve capacities in developing regions to help adaptation to climate change by taking advantage of Earth Observation data for decision making. The project began in 2004, in Mesoamerica, partnering with the Central American Commission for Environment and Development(CCAD), the World Bank and CATHALAC. CATHALAC, located in Panama, serves as the regional hub for Mesoamerica since 2005. Two additional regional hubs have been established (in Easters & Western Africa - at RCMRD, Kenya, and The Himalayas- at ICIMOD, Nepal), and two more regional hubs are soon to be launched.

  9. Augmenting a Ballet Dance Show Using the Dancer's Emotion: Conducting Joint Research in Dance and Computer Science

    NASA Astrophysics Data System (ADS)

    Clay, Alexis; Delord, Elric; Couture, Nadine; Domenger, Gaël

    We describe the joint research that we conduct in gesture-based emotion recognition and virtual augmentation of a stage, bridging together the fields of computer science and dance. After establishing a common ground for dialogue, we could conduct a research process that equally benefits both fields. As computer scientists, dance is a perfect application case. Dancer's artistic creativity orient our research choices. As dancers, computer science provides new tools for creativity, and more importantly a new point of view that forces us to reconsider dance from its fundamentals. In this paper we hence describe our scientific work and its implications on dance. We provide an overview of our system to augment a ballet stage, taking a dancer's emotion into account. To illustrate our work in both fields, we describe three events that mixed dance, emotion recognition and augmented reality.

  10. Biomechanical energy harvesting: generating electricity during walking with minimal user effort.

    PubMed

    Donelan, J M; Li, Q; Naing, V; Hoffer, J A; Weber, D J; Kuo, A D

    2008-02-08

    We have developed a biomechanical energy harvester that generates electricity during human walking with little extra effort. Unlike conventional human-powered generators that use positive muscle work, our technology assists muscles in performing negative work, analogous to regenerative braking in hybrid cars, where energy normally dissipated during braking drives a generator instead. The energy harvester mounts at the knee and selectively engages power generation at the end of the swing phase, thus assisting deceleration of the joint. Test subjects walking with one device on each leg produced an average of 5 watts of electricity, which is about 10 times that of shoe-mounted devices. The cost of harvesting-the additional metabolic power required to produce 1 watt of electricity-is less than one-eighth of that for conventional human power generation. Producing substantial electricity with little extra effort makes this method well-suited for charging powered prosthetic limbs and other portable medical devices.

  11. Degenerative joint disease: multiple joint involvement in young and mature dogs.

    PubMed

    Olsewski, J M; Lust, G; Rendano, V T; Summers, B A

    1983-07-01

    Radiologic, pathologic, and ancillary methods were used to determine the occurrence of degenerative joint disease involving multiple joints of immature and adult dogs. Animals were selected for the development of hip joint dysplasia and chronic degenerative joint disease. Of disease-prone dogs, 82% (45 of 55 dogs) had radiologic changes, indicative of hip dysplasia, by 1 year of age. At necropsy, more abnormal joints were identified than by radiographic examination. Among 92 dogs between 3 to 11 months of age that had joint abnormalities, 71% had hip joint involvement; 38%, shoulder joint involvement; 22%, stifle joint involvement; and 40% had multiple joint involvement. Polyarthritis was asymptomatic and unexpected. Radiographic examination of older dogs also revealed evidence of degenerative joint disease in many joints. Multiple joint involvement was substantiated at necropsy of young and mature dogs. A similar pattern of polyarticular osteoarthritis was revealed in a survey (computer search) of necropsy reports from medical case records of 100 adult and elderly dogs. Usually, the joint disease was an incidental observation, unrelated to the clinical disease or to the cause of death. The frequent occurrence of degenerative changes in several joints of dogs aged 6 months to 17 years indicated that osteoarthritis may be progressive in these joints and raises the possibility that systemic factors are involved in the disease process.

  12. Pelvic joint fusion in patients with severe pelvic girdle pain - a prospective single-subject research design study.

    PubMed

    Kibsgård, Thomas J; Røise, Olav; Stuge, Britt

    2014-03-15

    The fusion of the pelvic joints in patients with severe pelvic girdle pain (PGP) is a controversial and insufficiently studied procedure. The aims of this study were to evaluate physical function and pain after sacroiliac joint (SIJ) fusion. A single-subject research design study with repeated measurements was conducted; pre-operatively and at 3, 6 and 12 months post-operatively. The outcome measures considered were the Oswestry disability index (ODI), visual analogue scale (VAS), and SF-36. Eight patients with severe PGP received open-accessed unilateral anterior SIJ fusion and fusion of the pubic symphysis. Seven patients reported positive results from the surgery. At 1 year post-operation, significant (p < 0.001) reductions in ODI (54 to 37) and VAS (82 to 57) were reported. The physical functioning, bodily pain, and social functioning scores in the SF-36 were also improved. Positive and significant changes in disability and pain at 1 year after SIJ fusion were observed. Despite these positive results, open accessed anterior fusion of the SIJ was associated with adverse events and complications such as infection and nerve damage.

  13. An analysis of the diffusion of new antidepressants: variety, quality, and marketing efforts.

    PubMed

    Berndt, Ernst R; Bhattacharjya, Ashoke; Mishol, David N; Arcelus, Almudena; Lasky, Thomas

    2002-03-01

    We are not aware of any published research that quantifies and compares the importance of effectiveness and side effects for pharmaceutical sales, and that simultaneously incorporates the impacts of marketing efforts on the diffusion of new pharmaceutical agents in the U.S. The overall level and market share success of the various selective serotonin reuptake inhibitors ( SSRIs ) relative to a representative older generation tricyclic (such as amitriptyline) provides a useful focus for studying such issues. To model jointly the marketing and sales relationships of the SSRIs in the U.S., to quantify the extent to which marketing efforts are responsive to the availability of new scientific information accompanying changes in quality and increases in product variety, and in turn to assess how the new FDA indication approvals and the enhanced marketing initiatives involving product quality and variety affect sales of the SSRI and other novel antidepressants. Quarterly US sales, price, quantity and marketing data 1988Q1-1997Q4 are taken from IMS Health for the eight new antidepressants introduced into the US during this time period. Measures of physician-perceived quality attributes of the antidepressants are drawn from Market Measures, Inc., a medical survey research firm. These data are used to construct measures of product quality (effectiveness and side effect profile), and attribute variety across all antidepressants. Multivariate regression methods are used in estimating parameters of a marketing efforts model, a sales demand model encompassing the aggregate of the newer antidepressants, and a product share model. Simulation methods are employed to quantify elasticities. Since 1988, and relative to amitriptyline, there has been only a rather modest increase in the perceived average effectiveness of the SSRIs and related products, but the side effect profiles have improved substantially. Variety measures for effectiveness show greater increases over time than do

  14. Determination of Parachute Joint Factors using Seam and Joint Testing

    NASA Technical Reports Server (NTRS)

    Mollmann, Catherine

    2015-01-01

    This paper details the methodology for determining the joint factor for all parachute components. This method has been successfully implemented on the Capsule Parachute Assembly System (CPAS) for the NASA Orion crew module for use in determining the margin of safety for each component under peak loads. Also discussed are concepts behind the joint factor and what drives the loss of material strength at joints. The joint factor is defined as a "loss in joint strength...relative to the basic material strength" that occurs when "textiles are connected to each other or to metals." During the CPAS engineering development phase, a conservative joint factor of 0.80 was assumed for each parachute component. In order to refine this factor and eliminate excess conservatism, a seam and joint testing program was implemented as part of the structural validation. This method split each of the parachute structural joints into discrete tensile tests designed to duplicate the loading of each joint. Breaking strength data collected from destructive pull testing was then used to calculate the joint factor in the form of an efficiency. Joint efficiency is the percentage of the base material strength that remains after degradation due to sewing or interaction with other components; it is used interchangeably with joint factor in this paper. Parachute materials vary in type-mainly cord, tape, webbing, and cloth -which require different test fixtures and joint sample construction methods. This paper defines guidelines for designing and testing samples based on materials and test goals. Using the test methodology and analysis approach detailed in this paper, the minimum joint factor for each parachute component can be formulated. The joint factors can then be used to calculate the design factor and margin of safety for that component, a critical part of the design verification process.

  15. Influence of the Gap Width on the Geometry of the Welded Joint in Hybrid Laser-Arc Welding

    NASA Astrophysics Data System (ADS)

    Turichin, G.; Tsibulskiy, I.; Kuznetsov, M.; Akhmetov, A.; Mildebrath, M.; Hassel, T.

    The aim of this research was the experimental investigation of the influence of the gap width and speed of the welding wire on the changes of the geometry in the welded joint in the hybrid laser-arc welding of shipbuilding steel RS E36. The research was divided into three parts. First, in order to understand the influence of the gap width on the welded joint geometry, experimental research was done using continuous wave fiber laser IPG YLS-15000 with arc rectifier VDU-1500DC. The second part involved study of the geometry of the welded joint and hardness test results. Three macrosections from each welded joint were obtained. Influence of the gap width and welding wire speed on the welded joint geometry was researched in the three lines: in the right side of the plates, middle welded joint and in the root welded joint.

  16. Spacesuit mobility joints

    NASA Technical Reports Server (NTRS)

    Vykukal, H. C. (Inventor)

    1978-01-01

    Joints for use in interconnecting adjacent segments of an hermetically sealed spacesuit which have low torques, low leakage and a high degree of reliability are described. Each of the joints is a special purpose joint characterized by substantially constant volume and low torque characteristics. Linkages which restrain the joint from longitudinal distension and a flexible, substantially impermeable diaphragm of tubular configuration spanning the distance between pivotally supported annuli are featured. The diaphragms of selected joints include rolling convolutions for balancing the joints, while various joints include wedge-shaped sections which enhance the range of motion for the joints.

  17. 1998 Gordon Research Conference on Gravitational Effects on Living Systems

    NASA Technical Reports Server (NTRS)

    Evans, Michael L.

    1998-01-01

    The Gordon Research Conference (GRC) on GRAVITATIONAL EFFECTS ON LIVING SYSTEMS was held at COLBY SAYWER 2 from 7/12/98 thru 7/17/98. The Conference was well-attended with 94 participants. The attendees represented the spectrum of endeavor in this field coming from academia, industry, and government laboratories, both U.S. and foreign scientists, senior researchers, young investigators, and students. In designing the formal speakers program, emphasis was placed on current unpublished research and discussion of the future target areas in this field. There was a conscious effort to stimulate lively discussion about the key issues in the field today. Time for formal presentations was limited in the interest of group discussions. In order that more scientists could communicate their most recent results, poster presentation time was scheduled. A copy of the formal schedule and speaker program and the poster program is included. In addition to these formal interactions, "free time" was scheduled to allow informal discussions. Such discussions are fostering new collaborations and joint efforts in the field.

  18. Internet access to research results: an evolving effort

    Treesearch

    Daniel L. Schmoldt; Matthew F. Winn; Philip A. Araman

    2000-01-01

    Since October 1995, our Research Work Unit of the US Forest Service has operated a Web site to disseminate research results. Initially, this took the form of basic information about the Unit's goals, organization, research problems, cooperators, etc. Over time the site has expanded to provide lists of available publications, abstracts of those publications,...

  19. ATR NSUF Instrumentation Enhancement Efforts

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Joy L. Rempe; Mitchell K. Meyer; Darrell L. Knudson

    A key component of the Advanced Test Reactor (ATR) National Scientific User Facility (NSUF) effort is to expand instrumentation available to users conducting irradiation tests in this unique facility. In particular, development of sensors capable of providing real-time measurements of key irradiation parameters is emphasized because of their potential to increase data fidelity and reduce posttest examination costs. This paper describes the strategy for identifying new instrumentation needed for ATR irradiations and the program underway to develop and evaluate new sensors to address these needs. Accomplishments from this program are illustrated by describing new sensors now available to users ofmore » the ATR NSUF. In addition, progress is reported on current research efforts to provide improved in-pile instrumentation to users.« less

  20. Computer networks for financial activity management, control and statistics of databases of economic administration at the Joint Institute for Nuclear Research

    NASA Astrophysics Data System (ADS)

    Tyupikova, T. V.; Samoilov, V. N.

    2003-04-01

    Modern information technologies urge natural sciences to further development. But it comes together with evaluation of infrastructures, to spotlight favorable conditions for the development of science and financial base in order to prove and protect legally new research. Any scientific development entails accounting and legal protection. In the report, we consider a new direction in software, organization and control of common databases on the example of the electronic document handling, which functions in some departments of the Joint Institute for Nuclear Research.

  1. Building a Science Software Institute: Synthesizing the Lessons Learned from the ISEES and WSSI Software Institute Conceptualization Efforts

    NASA Astrophysics Data System (ADS)

    Idaszak, R.; Lenhardt, W. C.; Jones, M. B.; Ahalt, S.; Schildhauer, M.; Hampton, S. E.

    2014-12-01

    The NSF, in an effort to support the creation of sustainable science software, funded 16 science software institute conceptualization efforts. The goal of these conceptualization efforts is to explore approaches to creating the institutional, sociological, and physical infrastructures to support sustainable science software. This paper will present the lessons learned from two of these conceptualization efforts, the Institute for Sustainable Earth and Environmental Software (ISEES - http://isees.nceas.ucsb.edu) and the Water Science Software Institute (WSSI - http://waters2i2.org). ISEES is a multi-partner effort led by National Center for Ecological Analysis and Synthesis (NCEAS). WSSI, also a multi-partner effort, is led by the Renaissance Computing Institute (RENCI). The two conceptualization efforts have been collaborating due to the complementarity of their approaches and given the potential synergies of their science focus. ISEES and WSSI have engaged in a number of activities to address the challenges of science software such as workshops, hackathons, and coding efforts. More recently, the two institutes have also collaborated on joint activities including training, proposals, and papers. In addition to presenting lessons learned, this paper will synthesize across the two efforts to project a unified vision for a science software institute.

  2. Chronic bowel inflammation and inflammatory joint disease: Pathophysiology.

    PubMed

    Speca, Silvia; Dubuquoy, Laurent

    2017-07-01

    Bowel inflammation is closely linked to chronic joint inflammation. Research reported in the 1980s demonstrated bowel inflammation with gross and microscopic pathological features identical to those of Crohn's disease in over 60% of patients with spondyloarthritis (SpA). Numerous prospective studies have evidenced joint involvement in patients with chronic inflammatory bowel disease (IBD) and bowel inflammation in patients with SpA. Nevertheless, the interactions of joint disease and chronic bowel inflammation remain incompletely elucidated. Two main hypotheses have been suggested to explain potential links between inflammation of the mucosal immune system and peripheral arthritis: one identifies gut bacteria as potentially implicated in the development of joint inflammation and the other involves the recruitment of gut lymphocytes or activated macrophages to the joints. Pathophysiological investigations have established that HLA-B27 is a pivotal pathogenic factor. Here, we review current data on links between chronic bowel inflammation and inflammatory joint disease. Copyright © 2017 Société française de rhumatologie. Published by Elsevier SAS. All rights reserved.

  3. Evolution of Aerosol Research in India and the RAWEX–GVAX:An Overview

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Krishna Moorthy, K.; Satheesh, S. K.; Kotamarthi, V. R.

    Climate change has great significance in Asia in general, and India in particular; and atmospheric aerosols have a decisive role in this. The climate forcing potential of aerosols is closely linked to their optical, microphysical and chemical properties. Systematic efforts to characterize these properties over the Indian region started about 5 decades ago, and evolved over the years through concerted efforts in the form of long-term scientific programmes as well as concerted fields experiments. All these have resulted in this activity becoming one of the most vibrant fields of climate research in India and have brought several important issues inmore » the national and international foci. The field experiment, RAWEX-GVAX (Regional Aerosol Warming Experiment-Ganges Valley Aerosol Experiment), conducted during 2011-12 jointly by the US Department of Energy, Indian Space Research Organization and Department of Science and Technology, has emerged as a direct outcome of the above efforts. This overview provides a comprehensive account of the development of aerosol-climate research in India and south Asia, and the accomplishment and newer issues that warranted the above field campaign. Details of RAWEX-GVAX, the major outcomes and the subsequent and more recent efforts are presented, followed by the way forward in this field for the next several years to come.« less

  4. Neuromuscular prehabilitation to prevent osteoarthritis after a traumatic joint injury.

    PubMed

    Tenforde, Adam S; Shull, Pete B; Fredericson, Michael

    2012-05-01

    Post-traumatic osteoarthritis (PTOA) is a process resulting from direct forces applied to a joint that cause injury and degenerative changes. An estimated 12% of all symptomatic osteoarthritis (OA) of the hip, knee, and ankle can be attributed to a post-traumatic cause. Neuromuscular prehabilitation is the process of improving neuromuscular function to prevent development of PTOA after an initial traumatic joint injury. Prehabilitation strategies include restoration of normative movement patterns that have been altered as the result of traumatic injury, along with neuromuscular exercises and gait retraining to prevent the development of OA after an injury occurs. A review of the current literature shows that no studies have been performed to evaluate methods of neuromuscular prehabilitation to prevent PTOA after a joint injury. Instead, current research has focused on management strategies after knee injuries, the value of exercise in the management of OA, and neuromuscular exercises after total knee arthroplasty. Recent work in gait retraining that alters knee joint loading holds promise for preventing the development of PTOA after joint trauma. Future research should evaluate methods of neuromuscular prehabilitation strategies in relationship to the outcome of PTOA after joint injury. Copyright © 2012 American Academy of Physical Medicine and Rehabilitation. Published by Elsevier Inc. All rights reserved.

  5. Periprosthetic joint infection: are patients with multiple prosthetic joints at risk?

    PubMed

    Jafari, S Mehdi; Casper, David S; Restrepo, Camilo; Zmistowski, Benjamin; Parvizi, Javad; Sharkey, Peter F

    2012-06-01

    Patients who present with a periprosthetic joint infection in a single joint may have multiple prosthetic joints. The risk of these patients developing a subsequent infection in another prosthetic joint is unknown. Our purposes were (1) to identify the risk of developing a subsequent infection in another prosthetic joint and (2) to describe the time span and organism profile to the second prosthetic infection. We retrospectively identified 55 patients with periprosthetic joint infection who had another prosthetic joint in place at the time of presentation. Of the 55 patients, 11 (20%) developed a periprosthetic joint infection in a second joint. The type of organism was the same as the first infection in 4 (36%) of 11 patients. The time to developing a second infection averaged 2.0 years (range, 0-6.9 years). Copyright © 2012 Elsevier Inc. All rights reserved.

  6. Self-referenced processing, neurodevelopment and joint attention in autism.

    PubMed

    Mundy, Peter; Gwaltney, Mary; Henderson, Heather

    2010-09-01

    This article describes a parallel and distributed processing model (PDPM) of joint attention, self-referenced processing and autism. According to this model, autism involves early impairments in the capacity for rapid, integrated processing of self-referenced (proprioceptive and interoceptive) and other-referenced (exteroceptive) information. Measures of joint attention have proven useful in research on autism because they are sensitive to the early development of the 'parallel' and integrated processing of self- and other-referenced stimuli. Moreover, joint attention behaviors are a consequence, but also an organizer of the functional development of a distal distributed cortical system involving anterior networks including the prefrontal and insula cortices, as well as posterior neural networks including the temporal and parietal cortices. Measures of joint attention provide early behavioral indicators of atypical development in this parallel and distributed processing system in autism. In addition it is proposed that an early, chronic disturbance in the capacity for integrating self- and other-referenced information may have cascading effects on the development of self awareness in autism. The assumptions, empirical support and future research implications of this model are discussed.

  7. Integrated Knowledge Translation: illustrated with outcome research in mental health.

    PubMed

    Preyde, Michele; Carter, Jeff; Penney, Randy; Lazure, Kelly; Vanderkooy, John; Chevalier, Pat

    2015-01-01

    Through this article the authors present a case summary of the early phases of research conducted with an Integrated Knowledge Translation (iKT) approach utilizing four factors: research question, research approach, feasibility, and outcome. iKT refers to an approach for conducting research in which community partners, referred to as knowledge users, are engaged in the entire research process. In this collaborative approach, knowledge users and researchers jointly devise the entire research agenda beginning with the development of the research question(s), determination of a feasible research design and feasible methods, interpretation of the results, dissemination of the findings, and the translation of knowledge into practice or policy decisions. Engaging clinical or community partners in the research enterprise can enhance the utility of the research results and facilitate its uptake. This collaboration can be a complex arrangement and flexibility may be required to accommodate the various configurations that the collaboration can take. For example, the research question can be jointly determined and refined; however, one person must take the responsibility for orchestrating the project, including preparing the proposal and application to the Research Ethics Board. This collaborative effort also requires the simultaneous navigation of barriers and facilitators to the research enterprise. Navigating these elements becomes part of the conduct of research with the potential for rewarding results, including an enriched work experience for clinical partners and investigators. One practice implication is that iKT may be considered of great utility to service providers due to its field friendly nature.

  8. The collision forces and lower-extremity inter-joint coordination during running.

    PubMed

    Wang, Li-I; Gu, Chin-Yi; Wang, I-Lin; Siao, Sheng-Wun; Chen, Szu-Ting

    2018-06-01

    The purpose of this study was to compare the lower extremity inter-joint coordination of different collision forces runners during running braking phase. A dynamical system approach was used to analyse the inter-joint coordination parameters. Data were collected with six infra-red cameras and two force plates. According to the impact peak of the vertical ground reaction force, twenty habitually rearfoot-strike runners were categorised into three groups: high collision forces runners (HF group, n = 8), medium collision forces runners (MF group, n = 5), and low collision forces runners (LF group, n = 7). There were no significant differences among the three groups in the ankle and knee joint angle upon landing and in the running velocity (p > 0.05). The HF group produced significantly smaller deviation phase (DP) of the hip flexion/extension-knee flexion/extension during the braking phase compared with the MF and LF groups (p < 0.05). The DP of the hip flexion/extension-knee flexion/extension during the braking phase correlated negatively with the collision force (p < 0.05). The disparities regarding the flexibility of lower extremity inter-joint coordination were found in high collision forces runners. The efforts of the inter-joint coordination and the risk of running injuries need to be clarified further.

  9. The Joint Space Operations Center (JSpOC) Mission System (JMS) and the Advanced Research, Collaboration, and Application Development Environment (ARCADE)

    NASA Astrophysics Data System (ADS)

    Johnson, K.; Kim, R.; Echeverry, J.

    The Joint Space Operations Center (JSpOC) is a command and control center focused on executing the Space Control mission of the Joint Functional Component Command for Space (JFCC-SPACE) to ensure freedom of action of United States (US) space assets, while preventing adversary use of space against the US. To accomplish this, the JSpOC tasks a network of space surveillance sensors to collect Space Situational Awareness (SSA) data on resident space objects (RSOs) in near earth and deep space orbits. SSA involves the ingestion of data sources and use of algorithms and tools to build, maintain, and disseminate situational awareness of RSOs in space. On the heels of emergent and complex threats to space assets, the JSpOC's capabilities are limited by legacy systems and CONOPs. The JSpOC Mission System (JMS) aims to consolidate SSA efforts across US agencies, international partners, and commercial partners. The JMS program is intended to deliver a modern service-oriented architecture (SOA) based infrastructure with increased process automation and improved tools to remove the current barriers to JSpOC operations. JMS has been partitioned into several developmental increments. Increment 1, completed and operational in early 2013, and Increment 2, which is expected to be completed in 2016, will replace the legacy Space Defense Operations Center (SPADOC) and Astrodynamics Support Workstation (ASW) capabilities. In 2017 JMS Increment 3 will continue to provide additional SSA and C2 capabilities that will require development of new applications and procedures as well as the exploitation of new data sources. Most importantly, Increment 3 is uniquely postured to evolve the JSpOC into the centralized and authoritative source for all Space Control applications by using its SOA to aggregate information and capabilities from across the community. To achieve this goal, Scitor Corporation has supported the JMS Program Office as it has entered into a partnership with AFRL/RD (Directed

  10. Joint location, inventory, and preservation decisions for non-instantaneous deterioration items under delay in payments

    NASA Astrophysics Data System (ADS)

    Tsao, Yu-Chung

    2016-02-01

    This study models a joint location, inventory and preservation decision-making problem for non-instantaneous deteriorating items under delay in payments. An outside supplier provides a credit period to the wholesaler which has a distribution system with distribution centres (DCs). The non-instantaneous deteriorating means no deterioration occurs in the earlier stage, which is very useful for items such as fresh food and fruits. This paper also considers that the deteriorating rate will decrease and the reservation cost will increase as the preservation effort increases. Therefore, how much preservation effort should be made is a crucial decision. The objective of this paper is to determine the optimal locations and number of DCs, the optimal replenishment cycle time at DCs, and the optimal preservation effort simultaneously such that the total network profit is maximised. The problem is formulated as piecewise nonlinear functions and has three different cases. Algorithms based on piecewise nonlinear optimisation are provided to solve the joint location and inventory problem for all cases. Computational analysis illustrates the solution procedures and the impacts of the related parameters on decisions and profits. The results of this study can serve as references for business managers or administrators.

  11. Joint implementation: Biodiversity and greenhouse gas offsets

    NASA Astrophysics Data System (ADS)

    Cutright, Noel J.

    1996-11-01

    One of the most pressing environmental issues today is the possibility that projected increases in global emissions of greenhouse gases from increased deforestation, development, and fossil-fuel combustion could significantly alter global climate patterns. Under the terms of the United Nations Framework Convention on Climate Change, signed in Rio de Janeiro during the June 1992 Earth Summit, the United States and other industrialized countries committed to balancing greenhouse gas emissions at 1990 levels in the year 2000. Included in the treaty is a provision titled “Joint Implementation,” whereby industrialized countries assist developing countries in jointly modifying long-term emission trends, either through emission reductions or by protecting and enhancing greenhouse gas sinks (carbon sequestration). The US Climate Action Plan, signed by President Clinton in 1993, calls for voluntary climate change mitigation measures by various sectors, and the action plan included a new program, the US Initiative on Joint Implementation. Wisconsin Electric decided to invest in a Jl project because its concept encourages creative, cost-effective solutions to environmental problems through partnering, international cooperation, and innovation. The project chosen, a forest preservation and management effort in Belize, will sequester more than five million tons of carbon dioxide over a 40-year period, will become economically selfsustaining after ten years, and will have substantial biodiversity benefits.

  12. Joint Light Tactical Vehicle (JLTV): Background and Issues for Congress

    DTIC Science & Technology

    2017-01-10

    Joint Light Tactical Vehicle (JLTV): Background and Issues for Congress Andrew Feickert Specialist in Military Ground Forces January 10, 2017......Congressional Research Service Summary The Joint Light Tactical Vehicle (JLTV) is being developed by the Army and the Marine Corps as a successor to the High

  13. 78 FR 7464 - Large Scale Networking (LSN) ; Joint Engineering Team (JET)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-01

    ... NATIONAL SCIENCE FOUNDATION Large Scale Networking (LSN) ; Joint Engineering Team (JET) AGENCY: The Networking and Information Technology Research and Development (NITRD) National Coordination...://www.nitrd.gov/nitrdgroups/index.php?title=Joint_Engineering_Team_ (JET)#title. SUMMARY: The JET...

  14. Experimental investigation on frequency shifting of imperfect adhesively bonded pipe joints

    NASA Astrophysics Data System (ADS)

    Haiyam, F. N.; Hilmy, I.; Sulaeman, E.; Firdaus, T.; Adesta, E. Y. T.

    2018-01-01

    Inspection tests for any manufactured structure are compulsory in order to detect the existence of damage.It is to ensure the product integrity, reliability and to avoid further catastrophic failure. In this research, modal analysis was utilized to detect structural damage as one of the Non Destructive Testing (NDT) methods. Comparing the vibration signal of a healthy structure with a non-healthy signal was performed. A modal analysis of an adhesively bonded pipe joint was investigated with a healthy joint as a reference. The damage joint was engineered by inserting a nylon fiber, which act as an impurity at adhesive region. The impact test using hammer was utilized in this research. Identification of shifting frequency of a free supported and clamped pipe joint was performed.It was found that shifting frequency occurred to the lower side by 5%.

  15. Research on the Problem of High-Precision Deployment for Large-Aperture Space-Based Science Instruments

    NASA Technical Reports Server (NTRS)

    Lake, Mark S.; Peterson, Lee D.; Hachkowski, M. Roman; Hinkle, Jason D.; Hardaway, Lisa R.

    1998-01-01

    The present paper summarizes results from an ongoing research program conducted jointly by the University of Colorado and NASA Langley Research Center since 1994. This program has resulted in general guidelines for the design of high-precision deployment mechanisms, and tests of prototype deployable structures incorporating these mechanisms have shown microdynamically stable behavior (i.e., dimensional stability to parts per million). These advancements have resulted from the identification of numerous heretofore unknown microdynamic and micromechanical response phenomena, and the development of new test techniques and instrumentation systems to interrogate these phenomena. In addition, recent tests have begun to interrogate nanomechanical response of materials and joints and have been used to develop an understanding of nonlinear nanodynamic behavior in microdynamically stable structures. The ultimate goal of these efforts is to enable nano-precision active control of micro-precision deployable structures (i.e., active control to a resolution of parts per billion).

  16. From Effort to Value: Preschool Children's Alternative to Effort Justification.

    PubMed

    Benozio, Avi; Diesendruck, Gil

    2015-09-01

    In the current studies, we addressed the development of effort-based object valuation. Four- and 6-year-olds invested either great or little effort in order to obtain attractive or unattractive rewards. Children were allowed to allocate these rewards to an unfamiliar recipient (dictator game). Investing great effort to obtain attractive rewards (a consonant situation) led 6-year-olds, but not 4-year-olds, to enhance the value of the rewards and thus distribute fewer of them to others. After investing effort to attain unattractive rewards (a dissonant situation), 6-year-olds cognitively reduced the dissonance between effort and reward quality by reappraising the value of the rewards and thus distributing fewer of them. In contrast, 4-year-olds reduced the dissonance behaviorally by discarding the rewards. These findings provide evidence for the emergence of an effort-value link and underline possible mechanisms underlying the primacy of cognitive versus behavioral solutions to dissonance reduction. © The Author(s) 2015.

  17. Impact extractive fracture of jointed steel plates of a bolted joint

    NASA Astrophysics Data System (ADS)

    Daimaruya, M.; Fujiki, H.; Ambarita, H.

    2012-08-01

    This study is concerned with the development of a fracture criterion for the impact fracture of jointed steel plates of a bolted joint used in a car body. For the accurate prediction of crash characteristics of car bodies by computer-aided engineering (CAE), it is also necessary to examine the behavior and fracture of jointed steel plates subjected to impact loads. Although the actual impact fracture of jointed steel plates of a bolted joint used in cars is complicated, for simplifying the problem it might be classified into the shear fracture and the extractive fracture of jointed steel plates. Attention is given to the extractive fracture of jointed steel plates in this study. The extractive behavior and fracture of three kinds of steel plates used for cars are examined in experiments and numerical simulations. The impact extraction test of steel plates jointed by a bolt is performed using the one-bar method, together with the static test. In order to understand the mechanism of extractive fracture process of jointed steel plates, numerical simulations by a FEM code LS-DYNA are also carried out. The obtained results suggest that a stress-based fracture criterion may be developed for the impact extractive fracture of jointed steel plates of a bolted joint used in a car body.

  18. Engineering studies on joint bar integrity, part II : finite element analysis

    DOT National Transportation Integrated Search

    2014-04-02

    This paper is the second in a two-part series describing : research sponsored by the Federal Railroad Administration : (FRA) to study the structural integrity of joint bars. In Part I, : observations from field surveys of joint bar inspections : cond...

  19. The Interaction Between Punishment Sensitivity and Effortful Control for Emerging Adults' Substance Use Behaviors.

    PubMed

    Kahn, Rachel E; Chiu, Pearl H; Deater-Deckard, Kirby; Hochgraf, Anna K; King-Casas, Brooks; Kim-Spoon, Jungmeen

    2018-01-08

    Within the dual systems perspective, high reward sensitivity and low punishment sensitivity in conjunction with deficits in cognitive control may contribute to high levels of risk taking, such as substance use. The current study examined whether the individual components of effortful control (inhibitory control, attentional control, and activation control) serve as regulators and moderate the association between reward or punishment sensitivity and substance use behaviors. A total of 1,808 emerging adults from a university setting (Mean age = 19.48; 72% female) completed self-report measures of reward and punishment sensitivity, effortful control, and substance use. Findings indicated significant two-way interactions for punishment sensitivity and inhibitory control for alcohol and marijuana use. The form of these interactions revealed a significant negative association between punishment sensitivity and alcohol and marijuana use at low levels of inhibitory control. No significant interactions emerged for reward sensitivity or other components of effortful control. The current findings provide preliminary evidence suggesting the dual systems theorized to influence risk taking behavior interact to make joint contributions to health risk behaviors such as substance use in emerging adults.

  20. Dynamic analysis of clamp band joint system subjected to axial vibration

    NASA Astrophysics Data System (ADS)

    Qin, Z. Y.; Yan, S. Z.; Chu, F. L.

    2010-10-01

    Clamp band joints are commonly used for connecting circular components together in industry. Some of the systems jointed by clamp band are subjected to dynamic load. However, very little research on the dynamic characteristics for this kind of joint can be found in the literature. In this paper, a dynamic model for clamp band joint system is developed. Contact and frictional slip between the components are accommodated in this model. Nonlinear finite element analysis is conducted to identify the model parameters. Then static experiments are carried out on a scaled model of the clamp band joint to validate the joint model. Finally, the model is adopted to study the dynamic characteristics of the clamp band joint system subjected to axial harmonic excitation and the effects of the wedge angle of the clamp band joint and the preload on the response. The model proposed in this paper can represent the nonlinearity of the clamp band joint and be used conveniently to investigate the effects of the structural and loading parameters on the dynamic characteristics of this type of joint system.

  1. A novel hybrid joining methodology for composite to steel joints

    NASA Astrophysics Data System (ADS)

    Sarh, Bastian

    This research has established a novel approach for designing, analyzing, and fabricating load bearing structural connections between resin infused composite materials and components made of steel or other metals or alloys. A design philosophy is proposed wherein overlapping joint sections comprised of fiber reinforced plastics (FRP's) and steel members are connected via a combination of adhesive bonding and integrally placed composite pins. A film adhesive is utilized, placed into the dry stack prior to resin infusion and is cured after infusion through either local heat elements or by placing the structure into an oven. The novel manner in which the composite pins are introduced consists of perforating the steel member with holes and placing pre-formed composite pins through them, also prior to resin infusion of the composite section. In this manner joints are co-molded structures such that secondary processing is eliminated. It is shown that such joints blend the structural benefits of adhesive and mechanically connected joints, and that the fabrication process is feasible for low-cost, large-scale production as applicable to the shipbuilding industry. Analysis procedures used for designing such joints are presented consisting of an adhesive joint design theory and a pin placement theory. These analysis tools are used in the design of specimens, specific designs are fabricated, and these evaluated through structural tests. Structural tests include quasi-static loading and low cycle fatigue evaluation. This research has thereby invented a novel philosophy on joints, created the manufacturing technique for fabricating such joints, established simple to apply analysis procedures used in the design of such joints (consisting of both an adhesive and a pin placement analysis), and has validated the methodology through specimen fabrication and testing.

  2. Workload differences across command levels and emergency response organizations during a major joint training exercise.

    PubMed

    Prytz, Erik G; Rybing, Jonas; Jonson, Carl-Oscar

    2016-01-01

    This study reports on an initial test using a validated workload measurement method, the NASA Task Load Index (TLX), as an indicator of joint emergency exercise effectiveness. Prior research on emergency exercises indicates that exercises must be challenging, ie, result in high workload, to be effective. However, this is often problematic with some participants being underloaded and some overloaded. The NASA TLX was used to test for differences in workload between commanders and subordinates and among three different emergency response organizations during a joint emergency exercise. Questionnaire-based evaluation with professional emergency responders. The study was performed in conjunction with a large-scale interorganizational joint emergency exercise in Sweden. A total of 20 participants from the rescue services, 12 from the emergency medical services, and 12 from the police participated in the study (N=44). Ten participants had a command-level role during the exercise and the remaining 34 were subordinates. The main outcome measures were the workload subscales of the NASA TLX: mental demands, physical demands, temporal demands, performance, effort, and frustration. The results showed that the organizations experienced different levels of workload, that the commanders experienced a higher workload than the subordinates, and that two out of three organizations fell below the twenty-fifth percentile of average workload scores compiled from 237 prior studies. The results support the notion that the NASA TLX could be a useful complementary tool to evaluate exercise designs and outcomes. This should be further explored and verified in additional studies.

  3. OARSI Clinical Trials Recommendations: Design and conduct of clinical trials for primary prevention of osteoarthritis by joint injury prevention in sport and recreation.

    PubMed

    Emery, C A; Roos, E M; Verhagen, E; Finch, C F; Bennell, K L; Story, B; Spindler, K; Kemp, J; Lohmander, L S

    2015-05-01

    The risk of post-traumatic osteoarthritis (PTOA) substantially increases following joint injury. Research efforts should focus on investigating the efficacy of preventative strategies in high quality randomized controlled trials (RCT). The objective of these OARSI RCT recommendations is to inform the design, conduct and analytical approaches to RCTs evaluating the preventative effect of joint injury prevention strategies. Recommendations regarding the design, conduct, and reporting of RCTs evaluating injury prevention interventions were established based on the consensus of nine researchers internationally with expertise in epidemiology, injury prevention and/or osteoarthritis (OA). Input and resultant consensus was established through teleconference, face to face and email correspondence over a 1 year period. Recommendations for injury prevention RCTs include context specific considerations regarding the research question, research design, study participants, randomization, baseline characteristics, intervention, outcome measurement, analysis, implementation, cost evaluation, reporting and future considerations including the impact on development of PTOA. Methodological recommendations for injury prevention RCTs are critical to informing evidence-based practice and policy decisions in health care, public health and the community. Recommendations regarding the interpretation and conduct of injury prevention RCTs will inform the highest level of evidence in the field. These recommendations will facilitate between study comparisons to inform best practice in injury prevention that will have the greatest public health impact. Copyright © 2015 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved.

  4. SRB Environment Evaluation and Analysis. Volume 2: RSRB Joint Filling Test/Analysis Improvements

    NASA Technical Reports Server (NTRS)

    Knox, E. C.; Woods, G. Hamilton

    1991-01-01

    Following the Challenger accident a very comprehensive solid rocket booster (SRB) redesign program was initiated. One objective of the program was to develop expertise at NASA/MSFC in the techniques for analyzing the flow of hot gases in the SRB joints. Several test programs were undertaken to provide a data base of joint performance with manufactured defects in the joints to allow hot gases to fill the joints. This data base was used also to develop the analytical techniques. Some of the test programs were Joint Environment Simulator (JES), Nozzle Joint Environment Simulator (NJES), Transient Pressure Test Article (TPTA), and Seventy-Pound Charge (SPC). In 1988 the TPTA test hardware was moved from the Utah site to MSFC and several RSRM tests were scheduled, to be followed by tests for the ASRM program. REMTECH Inc. supported these activities with pretest estimates of the flow conditions in the test joints, and post-test analysis and evaluation of the measurements. During this support REMTECH identified deficiencies in the gas-measurement instrumentation that existed in the TPTA hardware, made recommendations for its replacement, and identified improvements to the analytical tools used in the test support. Only one test was completed under the TPTA RSRM test program, and those scheduled for the ASRM were rescheduled to a time after the expiration of this contract. The attention of this effort was directed toward improvements in the analytical techniques in preparation for when the ASRM program begins.

  5. Optimizing regional collaborative efforts to achieve long-term discipline-specific objectives

    USDA-ARS?s Scientific Manuscript database

    Current funding programs focused on multi-disciplinary, multi-agency approaches to regional issues can provide opportunities to address discipline-specific advancements in scientific knowledge. Projects funded through the Agricultural Research Service, Joint Fire Science Program, and the Natural Re...

  6. 76 FR 31305 - Pacific Whiting; Advisory Panel and Joint Management Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-31

    ... experienced in the harvesting, processing, marketing, management, conservation, or research of the offshore... Whiting; Advisory Panel and Joint Management Committee AGENCY: National Oceanic and Atmospheric.... SUMMARY: NMFS solicits nominations for the Advisory Panel (AP) and the Joint Management Committee (JMC) on...

  7. Common strategic research agenda for radiation protection in medicine.

    PubMed

    2017-04-01

    Reflecting the change in funding strategies for European research projects, and the goal to jointly improve medical radiation protection through sustainable research efforts, five medical societies involved in the application of ionising radiation (European Association of Nuclear Medicine, EANM; European Federation of Organizations for Medical Physics. EFOMP; European Federation of Radiographer Societies, EFRS; European Society of Radiology, ESR; European Society for Radiotherapy and Oncology, ESTRO) have identified research areas of common interest and developed this first edition of the Common Strategic Research Agenda (SRA) for medical radiation protection. The research topics considered necessary and most urgent for effective medical care and efficient in terms of radiation protection are summarised in five main themes: 1. Measurement and quantification in the field of medical applications of ionising radiation 2. Normal tissue reactions, radiation-induced morbidity and long-term health problems 3. Optimisation of radiation exposure and harmonisation of practices 4. Justification of the use of ionising radiation in medical practice 5. Infrastructures for quality assurance The SRA is a living document; thus comments and suggestions by all stakeholders in medical radiation protection are welcome and will be dealt with by the European Alliance for Medical Radiation Protection Research (EURAMED) established by the above-mentioned societies. • Overcome the fragmentation of medical radiation protection research in Europe • Identify research areas of joint interest in the field of medical radiation protection • Improve the use of ionising radiation in medicine • Collect stakeholder feedback and seek consensus • Emphasise importance of clinical translation and evaluation of research results.

  8. Implementation of a protein profiling platform developed as an academic-pharmaceutical industry collaborative effort.

    PubMed

    Végvári, Akos; Magnusson, Mattias; Wallman, Lars; Ekström, Simon; Bolmsjö, Gunnar; Nilsson, Johan; Miliotis, Tasso; Ostling, Jörgen; Kjellström, Sven; Ottervald, Jan; Franzén, Bo; Hultberg, Hans; Marko-Varga, György; Laurell, Thomas

    2008-06-01

    As much attention has devoted to the proteome research during the last few years, biomarker discovery has become an increasingly hot area, potentially enabling the development of new assays for diagnosis and prognosis of severe diseases. This is the field of research interest where efforts originating from both academic and industrial groups should jointly work on solutions. In this paper, we would like to demonstrate the fruitful combination of both research domains where the scientific crossroads sprout fresh ideas from the basic research domain and how these are refined and tethered to industrial standards. We will present an approach that is based on novel microfluidic devices, utilizing their benefits in processing small-volume samples. Our biomarker discovery strategy, built around this platform, involves optimized samples processing (based on SPE and sample enrichment) and fast MALDI-MS readout. The identification of novel biomarkers at low-abundance level has been achieved by the utilization of a miniaturized sample handling platform, which offers clean-up and enrichment of proteins in one step. Complete automation has been realized in the form of a unique robotic instrumentation that is able to extract and transfer 96 samples onto standard MALDI target plates with high throughput. The developed platform was operated with a 60 sample turnaround per hour allowing sensitivities in femtomol regions of medium- and low-abundant target proteins from clinical studies on samples of multiple sclerosis and gastroesophageal reflux disease. Several proteins have been identified as new biomarkers from cerebrospinal fluid and esophagus epithelial cells.

  9. 1998 Gordon Research Conference on Gravitational Effects on Living Systems

    NASA Technical Reports Server (NTRS)

    Evans, Michael L.

    1998-01-01

    The Gordon Research Conference (GRC) on GRAVITATIONAL EFFECTS ON LIVING SYSTEMS was held at COLBY SAYWER 2 from 7/12/98 thru 7/17/98. The Conference was well-attended with 94 participants (attendees list attached). The attendees represented the spectrum of endeavor in this field coming from academia, industry, and government laboratories, both U.S. and foreign scientists, senior researchers, young investigators, and students. In designing the formal speakers program, emphasis was placed on current unpublished research and discussion of the future target areas in this field. There was a conscious effort to stimulate lively discussion about the key issues in the field today. Time for formal presentations was limited in the interest of group discussions. In order that more scientists could communicate their most recent results, poster presentation time was scheduled. Attached is a copy of the formal schedule and speaker program and the poster program. In addition to these formal interactions, "free time" was scheduled to allow informal discussions. Such discussions are fostering new collaborations and joint efforts in the field. As you know, in the interest of promoting the presentation of unpublished and frontier-breaking research, Gordon Research Conferences does not permit publication of meeting proceedings.

  10. Joint Instability and Osteoarthritis

    PubMed Central

    Blalock, Darryl; Miller, Andrew; Tilley, Michael; Wang, Jinxi

    2015-01-01

    Joint instability creates a clinical and economic burden in the health care system. Injuries and disorders that directly damage the joint structure or lead to joint instability are highly associated with osteoarthritis (OA). Thus, understanding the physiology of joint stability and the mechanisms of joint instability-induced OA is of clinical significance. The first section of this review discusses the structure and function of major joint tissues, including periarticular muscles, which play a significant role in joint stability. Because the knee, ankle, and shoulder joints demonstrate a high incidence of ligament injury and joint instability, the second section summarizes the mechanisms of ligament injury-associated joint instability of these joints. The final section highlights the recent advances in the understanding of the mechanical and biological mechanisms of joint instability-induced OA. These advances may lead to new opportunities for clinical intervention in the prevention and early treatment of OA. PMID:25741184

  11. Joint instability and osteoarthritis.

    PubMed

    Blalock, Darryl; Miller, Andrew; Tilley, Michael; Wang, Jinxi

    2015-01-01

    Joint instability creates a clinical and economic burden in the health care system. Injuries and disorders that directly damage the joint structure or lead to joint instability are highly associated with osteoarthritis (OA). Thus, understanding the physiology of joint stability and the mechanisms of joint instability-induced OA is of clinical significance. The first section of this review discusses the structure and function of major joint tissues, including periarticular muscles, which play a significant role in joint stability. Because the knee, ankle, and shoulder joints demonstrate a high incidence of ligament injury and joint instability, the second section summarizes the mechanisms of ligament injury-associated joint instability of these joints. The final section highlights the recent advances in the understanding of the mechanical and biological mechanisms of joint instability-induced OA. These advances may lead to new opportunities for clinical intervention in the prevention and early treatment of OA.

  12. China's Efforts on Management, Surveillance, and Research of Noncommunicable Diseases: NCD Scorecard Project.

    PubMed

    Zhu, Xiao-Lei; Luo, Jie-Si; Zhang, Xiao-Chang; Zhai, Yi; Wu, Jing

    where China had the greatest need for improvement included increasing taxes on tobacco and addressing the needs of the population older than age 70 dying from major NCDs. In China the burden of disease of NCDs and disabilities remains serious, although China has put significant efforts into its governance and surveillance and research. To improve, further action is needed on reducing tobacco consumption, increasing investment in the national health budget, and increasing the focus on system construction. Copyright © 2017 Icahn School of Medicine at Mount Sinai. Published by Elsevier Inc. All rights reserved.

  13. Conversion of Indigenous Agricultural Waste Feedstocks to Fuel Ethanol. Cooperative Research and Development Final Report, CRADA Number CRD-13-504

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Elander, Richard

    This Cooperative Research and Development Agreement (CRADA) is between the National Renewable Energy Laboratory (NREL), a world leader in biomass conversion research and Ecopetrol American Inc., Ecopetrol S.A.'s U.S. subsidiary. The research and development efforts described in the Joint Work Statement (JWS) will take advantage of the strengths of both parties. NREL will use its Integrated Biorefinery Facility and vast experience in the conversion of lignocellulosic feedstocks to fuel ethanol to develop processes for the conversion of Ecopetrol's feedstocks. Ecopetrol will establish the infrastructure in Columbia to commercialize the conversion process.

  14. Key factors of clinical research network capacity building.

    PubMed

    Li, Guowei; Wu, Qianyu; Jin, Yanling; Vanniyasingam, Thuva; Thabane, Lehana

    2018-01-01

    In general, clinical research network capacity building refers to programs aimed at enhancing networks of researchers to conduct clinical research. Although in the literature there is a large body of research on how to develop and build capacity in clinical research networks, the conceptualizations and implementations remain controversial and challenging. Moreover, the experiences learnt from the past accomplishments and failures can assist in the future capacity building efforts to be more practical, effective and efficient. In this paper, we aim to provide an overview of capacity building in clinical research network by (1) identifying the key barriers to clinical research network capacity building, (2) providing insights into how to overcome those obstacles, and (3) sharing our experiences in collaborating with national and international partners to build capacity in clinical research networks. In conclusion, we have provided some insight into how to address the key factors of clinical research network capacity building and shared some empirical experiences. A successful capacity building practice requires a joint endeavor to procure sufficient resources and support from the relevant stakeholders, to ensure its efficiency, cost-effectiveness, and sustainability.

  15. Procedures and Concepts of EPA's Ongoing Sensor Evaluation Efforts

    EPA Science Inventory

    The purpose of this research effort was to develop an understanding of what technology might prove valuable in conducting the next generation of air monitoring. Upon their discovery, such technologies were obtained in collaboration with inventors and commercial and research orga...

  16. Towards computer-assisted surgery in shoulder joint replacement

    NASA Astrophysics Data System (ADS)

    Valstar, Edward R.; Botha, Charl P.; van der Glas, Marjolein; Rozing, Piet M.; van der Helm, Frans C. T.; Post, Frits H.; Vossepoel, Albert M.

    A research programme that aims to improve the state of the art in shoulder joint replacement surgery has been initiated at the Delft University of Technology. Development of improved endoprostheses for the upper extremities (DIPEX), as this effort is called, is a clinically driven multidisciplinary programme consisting of many contributory aspects. A part of this research programme focuses on the pre-operative planning and per-operative guidance issues. The ultimate goal of this part of the DIPEX project is to create a surgical support infrastructure that can be used to predict the optimal surgical protocol and can assist with the selection of the most suitable endoprosthesis for a particular patient. In the pre-operative planning phase, advanced biomechanical models of the endoprosthesis fixation and the musculo-skeletal system of the shoulder will be incorporated, which are adjusted to the individual's morphology. Subsequently, the support infrastructure must assist the surgeon during the operation in executing his surgical plan. In the per-operative phase, the chosen optimal position of the endoprosthesis can be realised using camera-assisted tools or mechanical guidance tools. In this article, the pathway towards the desired surgical support infrastructure is described. Furthermore, we discuss the pre-operative planning phase and the per-operative guidance phase, the initial work performed, and finally, possible approaches for improving prosthesis placement.

  17. North Carolina: Statewide Automation and Connectivity Efforts.

    ERIC Educational Resources Information Center

    Christian, Elaine J., Ed.

    1996-01-01

    Describes statewide information automation and connectivity efforts in North Carolina. Highlights include Triangle Research Libraries Network Document Delivery System; cooperative networking projects; public library connectivity to the state library; rural access projects; community college automation; K-12 technology plans; electronic government…

  18. Meeting at the Museum: Sustained Research Education Partnerships Start in Your Own Back Yard

    NASA Astrophysics Data System (ADS)

    Morin, P. J.; Hamilton, P.; Campbell, K. M.

    2007-12-01

    The Science Museum of Minnesota (SMM) and the National Center for Earth-surface Dynamics (NCED) have been formal partners since 2002, when we jointly secured NSF center-level funding. We began in our local community by together creating our own "Big Back Yard", a 1.75 acre outdoor park in which museum visitors, teachers and students explore natural and engineered river systems through miniature golf and interactive exhibits. We went on to jointly design "Earthscapes" programming for students, teachers and graduate students, related directly or indirectly to the park. From there, our partnership led to a major new exhibition that begins touring nationally and around the world in late 2007. A current effort seeks to bring NCED and SMM together with five other geo-science-oriented, NSF-supported Science and Technology Centers (STCs) from around the United States to develop collaborative means by which the research and science of all six STCs can reach larger informal science education audiences. We have learned a lot along the way about how museums can help individual and teams of researchers most effectively reach formal and informal audiences. Successful partnerships require significant joint commitment and funding, dedicated staff, and meaningful formative and summative evaluation. For a research center or an individual researcher, partnering with a museum provides experience, expertise, infrastructure, collegial relationships and community visibility that significantly enhance that of the academy. For a museum, one successful and highly visible research collaboration opens many new doors in the research community, providing new opportunities to broaden and deepen the scientific content of exhibits and programming.

  19. PCC/AC shoulder joint seal evaluation

    DOT National Transportation Integrated Search

    1999-05-07

    This report presents the findings on the evaluation of Crafco Incorporated Roadsaver 903 SL Silicone Sealant and Dow Corning 890 SL Silicone Sealant. The Research Technical Panel had proposed to use the two self-leveling silicone joint sealants in te...

  20. Understanding Motivators and Challenges to Involving Urban Parents as Collaborators in HIV Prevention Research Efforts.

    PubMed

    McKay, Mary M; Pinto, Rogério M; Bannon, William M; Guilamo-Ramos, Vincent

    2007-01-01

    This study was designed to explore the experiences of urban parents in their role as Collaborative Board members as part of the CHAMP (Collaborative HIV prevention and Adolescent Mental health Project) Family Program Study. The CHAMP Collaborative Board is comprised of urban parents, representatives from schools and community-based agencies and university-based researchers and is charged with overseeing the design, delivery and testing of a family-based HIV prevention program for pre and early adolescent youth. The current qualitative study, guided by the Theory of Unified Behavior Change, is meant to elucidate: (1) pathways to involvement by urban parents; (2) benefits and costs of participating in this collaborative HIV prevention research effort; and (3) the role of social relationships in influencing initial and ongoing participation by parent participants. Twenty-nine parent Collaborative Board members were interviewed for this study. In-depth interviews were audio recorded and ranged from 30 to 90 minutes in length. Transcripts were coded and analyzed using NUD*IST, computerized software used for examining narratives. Findings include community parent members identifying social support and learning opportunities as major reasons for involvement with the Collaborative Board. Prior involvement with other community-based projects and knowledge of at least one other person on the Board also influenced members to join the Board and remain involved over time. Further, recommendations for future collaborative partnerships are made. Findings have direct implication for participatory HIV prevention research activities.

  1. Astronomy in Cuba: practice and trends. An effort to develop a non-formal education programme

    NASA Astrophysics Data System (ADS)

    Pomares, Oscar A.

    In the recent past years, a daily stronger movement of non-professional astronomers has become the center of development for astronomy, a subject of study practically absent now from the national education system in Cuba. A key roll in this movement has been played by the professional staff of the Department of Astronomy of the Institute of Geophysics and Astronomy. As direct outcome of this joint effort between astronomers and amateurs is the research on meteors and comets, presented in two national and one international scientific meeetings. The opening last year of the "Palacio de las Ciencias" in the main building of the country, "El Capitolio Nacional", the participation in conferences and workshops of professional astronomers facing the general public, and their participation in prime-time TV and radio programs open a way for the growth of astronomical knowledge among the Cuban people. Two national meeetings gathering together professional and non- professional astronomers have been held already. Future works in the NEOs international campaign are foreseen. Practice and trends of astronomy in Cuba clarify views of our future in the oldest natural science.

  2. Evaluation of transverse joint forming methods for PCC pavement.

    DOT National Transportation Integrated Search

    2006-01-01

    The members of the Iowa Concrete Paving Association, the National Concrete Pavement Technology Center Research Committee, and : the Iowa Highway Research Board commissioned a study to examine alternative ways of developing transverse joints in portla...

  3. Research Notes. OERI's Regional Laboratory Technology Efforts.

    ERIC Educational Resources Information Center

    Garnette, Cheryl P., Ed.; Withrow, Frank B., Ed.

    1989-01-01

    Examines various educational technology projects that regional laboratories supported by the Office of Educational Research and Improvement (OERI) are undertaking. Highlights include innovative uses of instructional technology; tele-teaching using interactive audio conferencing; making informed decisions about technology; national teleconferences…

  4. Exploring Challenges and Opportunities of Coproduction: USDA Climate Hub Efforts to Integrate Coproduction with Applied Research and Decision Support Tool Development in the Northwest

    NASA Astrophysics Data System (ADS)

    Roesch-McNally, G.; Prendeville, H. R.

    2017-12-01

    A lack of coproduction, the joint production of new technologies or knowledge among technical experts and other groups, is arguably one of the reasons why much scientific information and resulting decision support systems are not very usable. Increasingly, public agencies and academic institutions are emphasizing the importance of coproduction of scientific knowledge and decision support systems in order to facilitate greater engagement between the scientific community and key stakeholder groups. Coproduction has been embraced as a way for the scientific community to develop actionable scientific information that will assist end users in solving real-world problems. Increasing the level of engagement and stakeholder buy-in to the scientific process is increasingly necessary, particularly in the context of growing politicization of science and the scientific process. Coproduction can be an effective way to build trust and can build-on and integrate local and traditional knowledge. Employing coproduction strategies may enable the development of more relevant and useful information and decision support tools that address stakeholder challenges at relevant scales. The USDA Northwest Climate Hub has increasingly sought ways to integrate coproduction in the development of both applied research projects and the development of decision support systems. Integrating coproduction, however, within existing institutions is not always simple, given that coproduction is often more focused on process than products and products are, for better or worse, often the primary focus of applied research and tool development projects. The USDA Northwest Climate Hub sought to integrate coproduction into our FY2017 call for proposal process. As a result we have a set of proposals and fledgling projects that fall along the engagement continuum (see Figure 1- attached). We will share the challenges and opportunities that emerged from this purposeful integration of coproduction into the work

  5. The hindlimb in walking horses: 2. Net joint moments and joint powers.

    PubMed

    Clayton, H M; Hodson, E; Lanovaz, J L; Colborne, G R

    2001-01-01

    The objective of the study was to describe net joint moments and joint powers in the equine hindlimb during walking. The subjects were 5 sound horses. Kinematic and force data were collected synchronously and combined with morphometric information to determine net joint moments at each hindlimb joint throughout stance and swing. The results showed that the net joint moment was on the caudal/plantar side of all hindlimb joints at the start of stance when the limb was being actively retracted. It moved to the cranial/dorsal side around 24% stride at the hip and stifle and in terminal stance at the more distal joints. It remained on the cranial/dorsal side of all joints during the first half of swing to provide active limb protraction, then moved to the caudal/plantar aspect to reverse the direction of limb motion prior to ground contact. The hip joint was the main source of energy generation throughout the stride. It was assisted by the tarsal joint in both stance and swing phases and by the fetlock joint during the stance phase. The coffin joint acted as an energy damper during stance, whereas the stifle joint absorbed almost equal amounts of energy in the stance and swing phases. The coffin and fetlock joints absorbed energy as the limb was protracted and retracted during the swing phase, suggesting that their movements were driven by inertial forces. Future studies will apply these findings to detect changes in the energy profiles due to specific soft tissue injuries.

  6. Temperature and Humidity Profiles in the TqJoint Data Group of AIRS Version 6 Product for the Climate Model Evaluation

    NASA Technical Reports Server (NTRS)

    Ding, Feng; Fang, Fan; Hearty, Thomas J.; Theobald, Michael; Vollmer, Bruce; Lynnes, Christopher

    2014-01-01

    The Atmospheric Infrared Sounder (AIRS) mission is entering its 13th year of global observations of the atmospheric state, including temperature and humidity profiles, outgoing long-wave radiation, cloud properties, and trace gases. Thus AIRS data have been widely used, among other things, for short-term climate research and observational component for model evaluation. One instance is the fifth phase of the Coupled Model Intercomparison Project (CMIP5) which uses AIRS version 5 data in the climate model evaluation. The NASA Goddard Earth Sciences Data and Information Services Center (GES DISC) is the home of processing, archiving, and distribution services for data from the AIRS mission. The GES DISC, in collaboration with the AIRS Project, released data from the version 6 algorithm in early 2013. The new algorithm represents a significant improvement over previous versions in terms of greater stability, yield, and quality of products. The ongoing Earth System Grid for next generation climate model research project, a collaborative effort of GES DISC and NASA JPL, will bring temperature and humidity profiles from AIRS version 6. The AIRS version 6 product adds a new "TqJoint" data group, which contains data for a common set of observations across water vapor and temperature at all atmospheric levels and is suitable for climate process studies. How different may the monthly temperature and humidity profiles in "TqJoint" group be from the "Standard" group where temperature and water vapor are not always valid at the same time? This study aims to answer the question by comprehensively comparing the temperature and humidity profiles from the "TqJoint" group and the "Standard" group. The comparison includes mean differences at different levels globally and over land and ocean. We are also working on examining the sampling differences between the "TqJoint" and "Standard" group using MERRA data.

  7. What Types of Students' Effort Are Rewarded with High Marks?

    ERIC Educational Resources Information Center

    Kelly, Sean

    2008-01-01

    This analysis of data from the Partnership for Literacy Study investigates the relationship among achievement, effort, and grades. Certainly, grades reward achievement, the mastery of material by students. Research has also suggested that grades are used to reward students for exerting effort to learn material, even if students fall short of…

  8. Private Speech Moderates the Effects of Effortful Control on Emotionality

    ERIC Educational Resources Information Center

    Day, Kimberly L.; Smith, Cynthia L.; Neal, Amy; Dunsmore, Julie C.

    2018-01-01

    Research Findings: In addition to being a regulatory strategy, children's private speech may enhance or interfere with their effortful control used to regulate emotion. The goal of the current study was to investigate whether children's private speech during a selective attention task moderated the relations of their effortful control to their…

  9. Defense Acquisitions: How DOD Acquires Weapon Systems and Recent Efforts to Reform the Process

    DTIC Science & Technology

    2010-04-23

    Departments; the Chairman, Joint Chiefs of Staff (CJCS) and Joint Staff; the Unified Combatant Commands ( UCCs ); the Defense Agencies; and DOD field...Systems Congressional Research Service 24 industrialists in their own states and districts got their fair share , or more, of the military contracts...be a market for its products as a catalyst; this market was born when the comparatively small and unsophisticated U.S. peacetime ‘militia’ envisioned

  10. A stochastic Iwan-type model for joint behavior variability modeling

    NASA Astrophysics Data System (ADS)

    Mignolet, Marc P.; Song, Pengchao; Wang, X. Q.

    2015-08-01

    This paper focuses overall on the development and validation of a stochastic model to describe the dissipation and stiffness properties of a bolted joint for which experimental data is available and exhibits a large scatter. An extension of the deterministic parallel-series Iwan model for the characterization of the force-displacement behavior of joints is first carried out. This new model involves dynamic and static coefficients of friction differing from each other and a broadly defined distribution of Jenkins elements. Its applicability is next investigated using the experimental data, i.e. stiffness and dissipation measurements obtained in harmonic testing of 9 nominally identical bolted joints. The model is found to provide a very good fit of the experimental data for each bolted joint notwithstanding the significant variability of their behavior. This finding suggests that this variability can be simulated through the randomization of only the parameters of the proposed Iwan-type model. The distribution of these parameters is next selected based on maximum entropy concepts and their corresponding parameters, i.e. the hyperparameters of the model, are identified using a maximum likelihood strategy. Proceeding with a Monte Carlo simulation of this stochastic Iwan model demonstrates that the experimental data fits well within the uncertainty band corresponding to the 5th and 95th percentiles of the model predictions which well supports the adequacy of the modeling effort.

  11. Defining the research agenda to reduce the joint burden of disease from Diabetes Mellitus and Tuberculosis

    PubMed Central

    Harries, Anthony D; Murray, Megan B; Jeon, Christie Y; Ottmani, Salah-Eddine; Lonnroth, Knut; Barreto, Mauricio L; Billo, Nils; Brostrom, Richard; Bygbjerg, Ib Christian; Fisher-Hoch, Susan; Mori, Toru; Ramaiya, Kaushik; Roglic, Gojka; Strandgaard, Hanne; Unwin, Nigel; Viswanathan, Vijay; Whiting, David; Kapur, Anil

    2015-01-01

    The steadily growing epidemic of diabetes mellitus (DM) poses a threat for global tuberculosis (TB) control. Previous studies have identified an important association between DM and TB. However, these studies have limitations: very few were carried out in low-income countries, with none in Africa, raising uncertainty about the strength of the DM-TB association in these settings, and many critical questions remain unanswered. An expert meeting was held in November 2009 to discuss where there was sufficient evidence to make firm recommendations about joint management of both diseases, to address research gaps and to develop a research agenda. Ten key research questions were identified, of which 4 were selected as high priority: i) whether, when and how to screen for TB in patients with DM and vice versa; ii) the impact of DM and non-DM hyperglycaemia on TB treatment outcomes and deaths, and the development of strategies to improve outcomes; iii) implementation and evaluation of the tuberculosis “DOTS” model for DM management; and iv) the development and evaluation of better point-of-care diagnostic and monitoring tests, including measurements of blood glucose and glycated haemoglobin A1c (HbA1c) for patients with DM. Implementation of this research agenda will benefit the control of both diseases. PMID:20406430

  12. A Web-based database for pathology faculty effort reporting.

    PubMed

    Dee, Fred R; Haugen, Thomas H; Wynn, Philip A; Leaven, Timothy C; Kemp, John D; Cohen, Michael B

    2008-04-01

    To ensure appropriate mission-based budgeting and equitable distribution of funds for faculty salaries, our compensation committee developed a pathology-specific effort reporting database. Principles included the following: (1) measurement should be done by web-based databases; (2) most entry should be done by departmental administration or be relational to other databases; (3) data entry categories should be aligned with funding streams; and (4) units of effort should be equal across categories of effort (service, teaching, research). MySQL was used for all data transactions (http://dev.mysql.com/downloads), and scripts were constructed using PERL (http://www.perl.org). Data are accessed with forms that correspond to fields in the database. The committee's work resulted in a novel database using pathology value units (PVUs) as a standard quantitative measure of effort for activities in an academic pathology department. The most common calculation was to estimate the number of hours required for a specific task, divide by 2080 hours (a Medicare year) and then multiply by 100. Other methods included assigning a baseline PVU for program, laboratory, or course directorship with an increment for each student or staff in that unit. With these methods, a faculty member should acquire approximately 100 PVUs. Some outcomes include (1) plotting PVUs versus salary to identify outliers for salary correction, (2) quantifying effort in activities outside the department, (3) documenting salary expenditure for unfunded research, (4) evaluating salary equity by plotting PVUs versus salary by sex, and (5) aggregating data by category of effort for mission-based budgeting and long-term planning.

  13. Effect of intraarticular tramadol administration in the rat model of knee joint inflammation.

    PubMed

    Garlicki, Jarosław; Dorazil-Dudzik, Magdalena; Wordliczek, Jerzy; Przewłocka, Barbara

    2006-01-01

    Local administration of exogenous opioids may cause effective analgesia without adverse symptoms from the central nervous system. Experiments show that peripheral antinociceptive effect of opioids is observed especially in inflammatory pain. The aim of the research was to estimate the effect of tramadol on nociceptive process at the level of peripheral nervous system, after its local administration in the model of knee joint inflammation. Tramadol was administered intraarticulary into the rat knee joint, before the inflammation as a preemptive analgesia and, for comparison, after the intraarticular injection of carrageenan. The research determined the influence of tramadol injection on pain threshold for thermal stimuli, development of inflammatory processes using the measurement of joint edema and motor function following the induction of knee joint inflammation in the rat. Functional assessment of knee joint with inflammation, in terms of rats' mobility and body position as well as joint loading and mobility were studied. The results of the experiments show that local administration of tramadol induces antinociceptive effect. The effect of tramadol, which elicits also a decrease in inflammatory edema, appears not only after its administration after carrageenan when inflammation was already present, but also in the case of its injection prior to carrageenan in the scheme of preemptive analgesia. The results of the described research show that not only morphine but also another opioid, tramadol, widely used in clinical practice, inhibits nociception, edema and functional impairment of the paw after its local application directly to the inflamed knee joint.

  14. Electronic Health Records: DOD and VA Should Remove Barriers and Improve Efforts to Meet Their Common System Needs

    DTIC Science & Technology

    2011-02-01

    and develop joint information technology (IT) capabilities for the James A. Lovell Federal Health Care Center ( FHCC ). In light of these efforts...Center to form the James A. Lovell Federal Health Care Center ( FHCC ) has prompted the departments to work toward implementing electronic health...information needs for the FHCC . To do this, GAO analyzed departmental reviews and other documentation and interviewed DOD and VA officials. What

  15. The Analysis of Adhesively Bonded Advanced Composite Joints Using Joint Finite Elements

    NASA Technical Reports Server (NTRS)

    Stapleton, Scott E.; Waas, Anthony M.

    2012-01-01

    The design and sizing of adhesively bonded joints has always been a major bottleneck in the design of composite vehicles. Dense finite element (FE) meshes are required to capture the full behavior of a joint numerically, but these dense meshes are impractical in vehicle-scale models where a course mesh is more desirable to make quick assessments and comparisons of different joint geometries. Analytical models are often helpful in sizing, but difficulties arise in coupling these models with full-vehicle FE models. Therefore, a joint FE was created which can be used within structural FE models to make quick assessments of bonded composite joints. The shape functions of the joint FE were found by solving the governing equations for a structural model for a joint. By analytically determining the shape functions of the joint FE, the complex joint behavior can be captured with very few elements. This joint FE was modified and used to consider adhesives with functionally graded material properties to reduce the peel stress concentrations located near adherend discontinuities. Several practical concerns impede the actual use of such adhesives. These include increased manufacturing complications, alterations to the grading due to adhesive flow during manufacturing, and whether changing the loading conditions significantly impact the effectiveness of the grading. An analytical study is conducted to address these three concerns. Furthermore, proof-of-concept testing is conducted to show the potential advantages of functionally graded adhesives. In this study, grading is achieved by strategically placing glass beads within the adhesive layer at different densities along the joint. Furthermore, the capability to model non-linear adhesive constitutive behavior with large rotations was developed, and progressive failure of the adhesive was modeled by re-meshing the joint as the adhesive fails. Results predicted using the joint FE was compared with experimental results for various

  16. Spacesuit mobility knee joints

    NASA Technical Reports Server (NTRS)

    Vykukal, H. C. (Inventor)

    1979-01-01

    Pressure suit mobility joints are for use in interconnecting adjacent segments of an hermetically sealed spacesuit in which low torques, low leakage and a high degree of reliability are required. Each of the joints is a special purpose joint characterized by substantially constant volume and low torque characteristics and includes linkages which restrain the joint from longitudinal distension and includes a flexible, substantially impermeable diaphragm of tubular configuration spanning the distance between pivotally supported annuli. The diaphragms of selected joints include rolling convolutions for balancing the joints, while various joints include wedge-shaped sections which enhance the range of motion for the joints.

  17. Joint Services Electronics Program.

    DTIC Science & Technology

    1980-05-01

    STATEMMEN A Approved for public release, COD Distribution Unlimited.99 Joint Services Electronics Program* _-ANNUAL PROGRESS RP O. 93) 7 / Covering Period...and the temperature dependence of that (dispersive transport) trap limited mobility has shown interesting new effects. Publications of the Research...Low-Cost Laboratory Computer Interface System," (Scheduled for publication May, 1980, Review ot Scinti’i3 Instruments). | i III. INFORMATION

  18. Perception of effort in Exercise Science: Definition, measurement and perspectives.

    PubMed

    Pageaux, Benjamin

    2016-11-01

    Perception of effort, also known as perceived exertion or sense of effort, can be described as a cognitive feeling of work associated with voluntary actions. The aim of the present review is to provide an overview of what is perception of effort in Exercise Science. Due to the addition of sensations other than effort in its definition, the neurophysiology of perceived exertion remains poorly understood. As humans have the ability to dissociate effort from other sensations related to physical exercise, the need to use a narrower definition is emphasised. Consequently, a definition and some brief guidelines for its measurement are provided. Finally, an overview of the models present in the literature aiming to explain its neurophysiology, and some perspectives for future research are offered.

  19. Joint Enabling Capabilities Command

    Science.gov Websites

    Executive Director Chief of Staff Joint Planning Support Element Joint Communications Support Element mission Joint Enabling Capabilities Command provides decisive joint communications, planning and public and responsive support for joint communications, planning and public affairs. Priorities * Deliver

  20. LDRD 2013 Annual Report: Laboratory Directed Research and Development Program Activities

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bookless, W.

    This LDRD project establishes a research program led by Jingguang Chen, who has started a new position as a Joint Appointee between BNL and Columbia University as of FY2013. Under this project, Dr. Chen will establish a new program in catalysis science at BNL and Columbia University. The LDRD program will provide initial research funding to start research at both BNL and Columbia. At BNL, Dr. Chen will initiate laboratory research, including hiring research staff, and will collaborate with the existing BNL catalysis and electrocatalysis research groups. At Columbia, a subcontract to Dr. Chen will provide startup funding for hismore » laboratory research, including initial graduate student costs. The research efforts will be linked under a common Catalysis Program in Sustainable Fuels. The overall impact of this project will be to strengthen the BNL catalysis science program through new linked research thrusts and the addition of an internationally distinguished catalysis scientist.« less

  1. Politics as Usual: The Joint Committee on Printing and Executive Agency Publishing, 1919-1921.

    ERIC Educational Resources Information Center

    Walters, John

    1993-01-01

    Provides an interpretation of the U.S. Congress Joint Committee on Printing (JCP) efforts to control departmental publishing from 1919 to 1921. Topics addressed include the JCP and the War Department, the role of the JCP in the defeat of the League of Nations, and the issue of separation of powers. (126 references) (LRW)

  2. Web-based Comparative Patient-reported Outcome Feedback to Support Quality Improvement and Comparative Effectiveness Research in Total Joint Replacement.

    PubMed

    Zheng, Hua; Li, Wenjun; Harrold, Leslie; Ayers, David C; Franklin, Patricia D

    2014-01-01

    Patient-reported outcomes (PROs) are rarely included in quality monitoring systems, surgeon comparative feedback reports, or registries. We present the design and implementation of a secure website in a federally funded research program-Function and Outcomes Research for Comparative Effectiveness in Total Joint Replacement (FORCE-TJR)-to return comparative PRO reports to participating surgeons, in addition to including traditional quality measures, in order to monitor and improve quality and health outcomes. The surgeon-specific comparative PRO reports were designed and structured based on user input for content, data elements, integration, and display. Three questions are addressed regarding the knee and hip joint symptom profiles of patients before TJR, as well as outcomes of surgery. The website is organized with a hierarchical structure to display data at national, practice, and individual surgeon levels, and provides a comprehensive site-level executive summary and surgeon-level data reports that can be downloaded. As of September 2014, over 22,000 patients were enrolled from more than 130 surgeons in 22 states. The reporting website was launched in September 2012 and has been updated quarterly for all surgeons to review their site- and individual-specific outcomes data compared to national benchmarks. In this novel system, quarterly comparative surgeon feedback extends beyond traditional measures of complication rates to include PROs of pain relief and functional gain. We anticipate that this enhanced data will facilitate patient-centered quality improvement (QI) and outcomes research from the registry. As the Centers for Medicare & Medicaid Services (CMS) and other insurers consider future implementation of PROs, surgeons will increasingly need comparative data by which to self-monitor their practice outcomes.

  3. The Joint European Compound Library: boosting precompetitive research.

    PubMed

    Besnard, Jérémy; Jones, Philip S; Hopkins, Andrew L; Pannifer, Andrew D

    2015-02-01

    The Joint European Compound Library (JECL) is a new high-throughput screening collection aimed at driving precompetitive drug discovery and target validation. The JECL has been established with a core of over 321,000 compounds from the proprietary collections of seven pharmaceutical companies and will expand to around 500,000 compounds. Here, we analyse the physicochemical profile and chemical diversity of the core collection, showing that the collection is diverse and has a broad spectrum of predicted biological activity. We also describe a model for sharing compound information from multiple proprietary collections, enabling diversity and quality analysis without disclosing structures. The JECL is available for screening at no cost to European academic laboratories and SMEs through the IMI European Lead Factory (http://www.europeanleadfactory.eu/). Copyright © 2014 The Authors. Published by Elsevier Ltd.. All rights reserved.

  4. POEM: Identifying Joint Additive Effects on Regulatory Circuits.

    PubMed

    Botzman, Maya; Nachshon, Aharon; Brodt, Avital; Gat-Viks, Irit

    2016-01-01

    Expression Quantitative Trait Locus (eQTL) mapping tackles the problem of identifying variation in DNA sequence that have an effect on the transcriptional regulatory network. Major computational efforts are aimed at characterizing the joint effects of several eQTLs acting in concert to govern the expression of the same genes. Yet, progress toward a comprehensive prediction of such joint effects is limited. For example, existing eQTL methods commonly discover interacting loci affecting the expression levels of a module of co-regulated genes. Such "modularization" approaches, however, are focused on epistatic relations and thus have limited utility for the case of additive (non-epistatic) effects. Here we present POEM (Pairwise effect On Expression Modules), a methodology for identifying pairwise eQTL effects on gene modules. POEM is specifically designed to achieve high performance in the case of additive joint effects. We applied POEM to transcription profiles measured in bone marrow-derived dendritic cells across a population of genotyped mice. Our study reveals widespread additive, trans-acting pairwise effects on gene modules, characterizes their organizational principles, and highlights high-order interconnections between modules within the immune signaling network. These analyses elucidate the central role of additive pairwise effect in regulatory circuits, and provide computational tools for future investigations into the interplay between eQTLs. The software described in this article is available at csgi.tau.ac.il/POEM/.

  5. Joint Assessment of Renewable Energy and Water Desalination Research Center (REWDC) Program Capabilities and Facilities In Radioactive Waste Management

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bissani, M; Fischer, R; Kidd, S

    2006-04-03

    The primary goal of this visit was to perform a joint assessment of the Renewable Energy and Water Desalination Center's (REWDC) program in radioactive waste management. The visit represented the fourth technical and scientific interaction with Libya under the DOE/NNSA Sister Laboratory Arrangement. Specific topics addressed during the visit focused on Action Sheet P-05-5, ''Radioactive Waste Management''. The Team, comprised of Mo Bissani (Team Lead), Robert Fischer, Scott Kidd, and Jim Merrigan, consulted with REWDC management and staff. The team collected information, discussed particulars of the technical collaboration and toured the Tajura facility. The tour included the waste treatment facility,more » waste storage/disposal facility, research reactor facility, hot cells and analytical labs. The assessment team conducted the first phase of Task A for Action Sheet 5, which involved a joint assessment of the Radioactive Waste Management Program. The assessment included review of the facilities dedicated to the management of radioactive waste at the Tourja site, the waste management practices, proposed projects for the facility and potential impacts on waste generation and management.« less

  6. Pelvic joint fusion in patients with severe pelvic girdle pain – a prospective single-subject research design study

    PubMed Central

    2014-01-01

    Background The fusion of the pelvic joints in patients with severe pelvic girdle pain (PGP) is a controversial and insufficiently studied procedure. The aims of this study were to evaluate physical function and pain after sacroiliac joint (SIJ) fusion. Methods A single-subject research design study with repeated measurements was conducted; pre-operatively and at 3, 6 and 12 months post-operatively. The outcome measures considered were the Oswestry disability index (ODI), visual analogue scale (VAS), and SF-36. Eight patients with severe PGP received open-accessed unilateral anterior SIJ fusion and fusion of the pubic symphysis. Results Seven patients reported positive results from the surgery. At 1 year post-operation, significant (p < 0.001) reductions in ODI (54 to 37) and VAS (82 to 57) were reported. The physical functioning, bodily pain, and social functioning scores in the SF-36 were also improved. Conclusion Positive and significant changes in disability and pain at 1 year after SIJ fusion were observed. Despite these positive results, open accessed anterior fusion of the SIJ was associated with adverse events and complications such as infection and nerve damage. PMID:24629145

  7. Development of Bonded Joint Technology for a Rigidizable-Inflatable Deployable Truss

    NASA Technical Reports Server (NTRS)

    Smeltzer, Stanley S., III

    2006-01-01

    Microwave and Synthetic Aperture Radar antenna systems have been developed as instrument systems using truss structures as their primary support and deployment mechanism for over a decade. NASA Langley Research Center has been investigating fabrication, modular assembly, and deployment methods of lightweight rigidizable/inflatable linear truss structures during that time for large spacecraft systems. The primary goal of the research at Langley Research Center is to advance these existing state-of-the-art joining and deployment concepts to achieve prototype system performance in a relevant space environment. During 2005, the development, fabrication, and testing of a 6.7 meter multi-bay, deployable linear truss was conducted at Langley Research Center to demonstrate functional and precision metrics of a rigidizable/inflatable truss structure. The present paper is intended to summarize aspects of bonded joint technology developed for the 6.7 meter deployable linear truss structure while providing a brief overview of the entire truss fabrication, assembly, and deployment methodology. A description of the basic joint design, surface preparation investigations, and experimental joint testing of component joint test articles will be described. Specifically, the performance of two room temperature adhesives were investigated to obtain qualitative data related to tube folding testing and quantitative data related to tensile shear strength testing. It was determined from the testing that a polyurethane-based adhesive best met the rigidizable/inflatable truss project requirements.

  8. MP Joint Arthritis

    MedlinePlus

    ... is extensive and severe, joint replacement or joint fusion are effective surgical options. Learn more about joint ... the tabs at the top (Video, Articles/WEB, Images, JHS, Products/Vendors), or the filters on the ...

  9. A Systematic Approach to the Study of Accelerated weathering of Building Joint Sealants

    Treesearch

    Christopher C. White; Donald L. Hunston; Kar Tean Tan; James J. Filliben; Adam L. Pintar; Greg Schueneman

    2012-01-01

    An accurate service life prediction model is needed for building joint sealants in order to greatly reduce the time to market of a new product and reduce the risk of introducing a poorly performing product into the marketplace. A stepping stone to the success of this effort is the precise control of environmental variables in a laboratory accelerated test apparatus in...

  10. SUMMARY OF JOINT DOD, EPA RESEARCH TO CONTROL VOC AND TOXIC EMISSIONS

    EPA Science Inventory

    The paper summarizes the results of joint projects conducted during last 6 years by the Department of Defense and EPA to control volatile organic compounds (VOCs) and toxic emissions. ajor emphasis has been on product coating and metal finishing: (1) paint stripping using plastic...

  11. Computer simulation of solder joint failure

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Burchett, S.N.; Frear, D.R.; Rashid, M.M.

    The thermomechanical fatigue failure of solder joints is increasingly becoming an important reliability issue for electronic packages. The purpose of this Laboratory Directed Research and Development (LDRD) project was to develop computational tools for simulating the behavior of solder joints under strain and temperature cycling, taking into account the microstructural heterogeneities that exist in as-solidified near eutectic Sn-Pb joints, as well as subsequent microstructural evolution. The authors present two computational constitutive models, a two-phase model and a single-phase model, that were developed to predict the behavior of near eutectic Sn-Pb solder joints under fatigue conditions. Unique metallurgical tests provide themore » fundamental input for the constitutive relations. The two-phase model mathematically predicts the heterogeneous coarsening behavior of near eutectic Sn-Pb solder. The finite element simulations with this model agree qualitatively with experimental thermomechanical fatigue tests. The simulations show that the presence of an initial heterogeneity in the solder microstructure could significantly degrade the fatigue lifetime. The single-phase model was developed to predict solder joint behavior using materials data for constitutive relation constants that could be determined through straightforward metallurgical experiments. Special thermomechanical fatigue tests were developed to give fundamental materials input to the models, and an in situ SEM thermomechanical fatigue test system was developed to characterize microstructural evolution and the mechanical behavior of solder joints during the test. A shear/torsion test sample was developed to impose strain in two different orientations. Materials constants were derived from these tests. The simulation results from the two-phase model showed good fit to the experimental test results.« less

  12. Thermal Barriers Developed for Solid Rocket Motor Nozzle Joints

    NASA Technical Reports Server (NTRS)

    Steinetz, Bruce M.; Dunlap, Patrick H., Jr.

    2000-01-01

    Space shuttle solid rocket motor case assembly joints are sealed with conventional O-ring seals that are shielded from 5500 F combustion gases by thick layers of insulation and by special joint-fill compounds that fill assembly splitlines in the insulation. On a number of occasions, NASA has observed hot gas penetration through defects in the joint-fill compound of several of the rocket nozzle assembly joints. In the current nozzle-to-case joint, NASA has observed penetration of hot combustion gases through the joint-fill compound to the inboard wiper O-ring in one out of seven motors. Although this condition does not threaten motor safety, evidence of hot gas penetration to the wiper O-ring results in extensive reviews before resuming flight. The solid rocket motor manufacturer (Thiokol) approached the NASA Glenn Research Center at Lewis Field about the possibility of applying Glenn's braided fiber preform seal as a thermal barrier to protect the O-ring seals. Glenn and Thiokol are working to improve the nozzle-to-case joint design by implementing a more reliable J-leg design and by using a braided carbon fiber thermal barrier that would resist any hot gases that the J-leg does not block.

  13. Activation of selected shoulder muscles during unilateral wall and bench press tasks under submaximal isometric effort.

    PubMed

    Tucci, Helga T; Ciol, Marcia A; de Araújo, Rodrigo C; de Andrade, Rodrigo; Martins, Jaqueline; McQuade, Kevin J; Oliveira, Anamaria S

    2011-07-01

    Controlled laboratory study. To assess the activation of 7 shoulder muscles under 2 closed kinetic chain (CKC) tasks for the upper extremity using submaximal isometric effort, thus providing relative quantification of muscular isometric effort for these muscles across the CKC exercises, which may be applied to rehabilitation protocols for individuals with shoulder weakness. CKC exercises favor joint congruence, reduce shear load, and promote joint dynamic stability. Additionally, knowledge about glenohumeral and periscapular muscle activity elicited during CKC exercises may help clinicians to design protocols for shoulder rehabilitation. Using surface electromyography, activation level was measured across 7 shoulder muscles in 20 healthy males, during the performance of a submaximal isometric wall press and bench press. Signals were normalized to the maximal voluntary isometric contraction, and, using paired t tests, data were analyzed between the exercises for each muscle. Compared to the wall press, the bench press elicited higher activity for most muscles, except for the upper trapezius. Levels of activity were usually low but were above 20% maximal voluntary isometric contraction for the serratus anterior on both tasks, and for the long head triceps brachii on the bench press. Both the bench press and wall press, as performed in this study, led to relatively low EMG activation levels for the muscles measured and may be considered for use in the early phases of rehabilitation.

  14. Operational space weather product development and validation at the joint SMC-AFRL Rapid Prototyping Center

    NASA Astrophysics Data System (ADS)

    Quigley, S.

    The Air Force Research Laboratory (AFRL/VSB) and Detachment 11, Space &Missile Systems Center (SMC, Det 11/CIT) have combined efforts to design, develop, test, and implement graphical products for the Air Force's space weather operations center. These products are generated to analyze, specify, and forecast the effects of the near-earth space environment on Department of Defense systems and communications. Jointly-developed products that have been, or will soon be added to real-time operations include: 1) the Operational Space Environment Network Display (OpSEND) suit - a set of four products that address HF communication, UHF satellite communication scintillation, radar auroral clutter, and GP S single- frequency errors; 2) a solar radio background and burst effects (SoRBE) product suite; and C) a meteor effects (ME) product suite. The RPC is also involved in a rather substantial "V&V" effort to produce multiple operational product verifications and validations, with an added end goal of a generalized validation software package. The presentation will provide a general overview of the RPC and each of the products mentioned above, to include background science, operational history, inputs, outputs, dissemination, and customer uses for each.

  15. Cognitive Load and Listening Effort: Concepts and Age-Related Considerations.

    PubMed

    Lemke, Ulrike; Besser, Jana

    2016-01-01

    Listening effort has been recognized as an important dimension of everyday listening, especially with regard to the comprehension of spoken language. At constant levels of comprehension performance, the level of effort exerted and perceived during listening can differ considerably across listeners and situations. In this article, listening effort is used as an umbrella term for two different types of effort that can arise during listening. One of these types is processing effort, which is used to denote the utilization of "extra" mental processing resources in listening conditions that are adverse for an individual. A conceptual description is introduced how processing effort could be defined in terms of situational influences, the listener's auditory and cognitive resources, and the listener's personal state. Also, the proposed relationship between processing effort and subjectively perceived listening effort is discussed. Notably, previous research has shown that the availability of mental resources, as well as the ability to use them efficiently, changes over the course of adult aging. These common age-related changes in cognitive abilities and their neurocognitive organization are discussed in the context of the presented concept, especially regarding situations in which listening effort may be increased for older people.

  16. Beyond Coordination: Joint Planning and Program Execution. The IHPRPT Materials Working Group

    NASA Technical Reports Server (NTRS)

    Stropki, Michael A.; Cleyrat, Danial A.; Clinton, Raymond G., Jr.; Rogacki, John R. (Technical Monitor)

    2000-01-01

    "Partnership is more than just coordination," stated then-Commander of the Air Force Research Laboratory (AFRL), Major General Dick Paul (USAF-Ret), at this year's National Space and Missile Materials Symposium. His comment referred to the example of the joint planning and program execution provided by the Integrated High Payoff Rocket Propulsion Technology (IHPRPT) Materials Working Group (IMWG). Most people agree that fiscal pressures imposed by shrinking budgets have made it extremely difficult to build upon our existing technical capabilities. In times of sufficient budgets, building advanced systems poses no major difficulties. However, with today's budgets, realizing enhanced capabilities and developing advanced systems often comes at an unaffordable cost. Overcoming this problem represents both a challenge and an opportunity to develop new business practices that allow us to develop advanced technologies within the restrictions imposed by current funding levels. Coordination of technology developments between different government agencies and organizations is a valuable tool for technology transfer. However, rarely do the newly developed technologies have direct applicability to other ongoing programs. Technology requirements are typically determined up-front during the program planning stage so that schedule risk can be minimized. The problem with this process is that the costs associated with the technology development are often borne by a single program. Additionally, the potential exists for duplication of technical effort. Changing this paradigm is a difficult process but one that can be extremely worthwhile should the right opportunity arise. The IMWG is one such example where NASA, the DoD, and industry have developed joint requirements that are intended to satisfy multiple program needs. More than mere coordination, the organizations comprising the group come together as partners, sharing information and resources, proceeding from a joint roadmap.

  17. Thermal imaging in screening of joint inflammation and rheumatoid arthritis in children.

    PubMed

    Lasanen, R; Piippo-Savolainen, E; Remes-Pakarinen, T; Kröger, L; Heikkilä, A; Julkunen, P; Karhu, J; Töyräs, J

    2015-02-01

    Potential of modern thermal imaging for screening and differentiation of joint inflammation has not been assessed in child and juvenile patient populations, typically demanding groups in diagnostics of musculoskeletal disorders. We hypothesize that thermal imaging can detect joint inflammation in patients with juvenile idiopathic arthritis or autoimmune disease with arthritis such as systemic lupus erythematosus. To evaluate the hypothesis, we studied 58 children exhibiting symptoms of joint inflammation. First, the patients' joints were examined along clinical procedure supplemented with ultrasound imaging when deemed necessary by the clinician. Second, thermal images were acquired from patients' knees and ankles. Results of thermal imaging were compared to clinical evaluations in knee and ankle. The temperatures were significantly (pmax = 0.044, pmean < 0.001) higher in inflamed ankle joints, but not in inflamed knee joints. No significant difference was found between the skin surface temperatures of medial and lateral aspects of ankle joints. In knee joints the mean temperatures of medial and lateral aspect differed significantly (p = 0.004). We have demonstrated that thermal imaging may have potential for detecting joint inflammation in ankle joints of children. For knee joints our results are inconclusive and further research is warranted.

  18. Gear noise, vibration, and diagnostic studies at NASA Lewis Research Center

    NASA Technical Reports Server (NTRS)

    Zakrajsek, James J.; Oswald, Fred B.; Townsend, Dennis P.; Coy, John J.

    1990-01-01

    The NASA Lewis Research Center and the U.S. Army Aviation Systems Command are involved in a joint research program to advance the technology of rotorcraft transmissions. This program consists of analytical as well as experimental efforts to achieve the overall goals of reducing weight, noise, and vibration, while increasing life and reliability. Recent analytical activities are highlighted in the areas of gear noise, vibration, and diagnostics performed in-house and through NASA and U.S. Army sponsored grants and contracts. These activities include studies of gear tooth profiles to reduce transmission error and vibration as well as gear housing and rotordynamic modeling to reduce structural vibration transmission and noise radiation, and basic research into current gear failure diagnostic methodologies. Results of these activities are presented along with an overview of near term research plans in the gear noise, vibration, and diagnostics area.

  19. Magneto-therapy of human joint cartilage.

    PubMed

    Wierzcholski, Krzysztof; Miszczak, Andrzej

    2017-01-01

    The topic of the present paper concerns the human joint cartilage therapy performed by the magnetic induction field. There is proved the thesis that the applied magnetic field for concrete cartilage illness should depend on the proper relative and concrete values of applied magnetic induction, intensity as well the time of treatment duration. Additionally, very important are frequencies and amplitudes of magnetic field as well as magnetic permeability of the synovial fluid. The research methods used in this paper include: magnetic induction field produced by a new Polish and German magneto electronic devices for the therapy of human joint cartilage diseases, stationary and movable magnetic applicators, magnetic bandage, ferrofluid injections, author's experience gained in Germany research institutes and practical results after measurements and information from patients. The results of this paper concern concrete parameters of time dependent electro-magnetic field administration during the joint cartilage therapy duration and additionally concern the corollaries which are implied from reading values gained on the magnetic induction devices. The main conclusions obtained in this paper are as follows: Time dependent magnetic induction field increases the dynamic viscosity of movable synovial fluid and decreases symptoms of cartilage illness for concrete intensity of magnetic field and concrete field line architecture. The ferrofluid therapy and phospholipids bilayer simultaneously with the administrated external electromagnetic field, increases the dynamic viscosity of movable synovial fluid.

  20. Correcting the record of structural publications requires joint effort of the community and journal editors.

    PubMed

    Rupp, Bernhard; Wlodawer, Alexander; Minor, Wladek; Helliwell, John R; Jaskolski, Mariusz

    2016-12-01

    Seriously flawed and even fictional models of biomolecular crystal structures, although rare, still persist in the record of structural repositories and databases. The ensuing problems of database contamination and persistence of publications based on incorrect structure models must be effectively addressed. The burden cannot be simply left to the critical voices who take the effort to contribute dissenting comments that are mostly ignored. The entire structural biology community, and particularly the journal editors who exercise significant power in this respect, must engage in a constructive dialog lest structural biology lose its credibility as an evidence-based empirical science. © 2016 Federation of European Biochemical Societies.

  1. Joint US Geological Survey, US Nuclear Regulatory Commission workshop on research related to low-level radioactive waste disposal, May 4-6, 1993, National Center, Reston, Virginia; Proceedings

    USGS Publications Warehouse

    Stevens, Peter R.; Nicholson, Thomas J.

    1996-01-01

    This report contains papers presented at the "Joint U.S. Geological Survey (USGS) and U.S. Nuclear Regulatory Commission (NRC) Technical Workshop on Research Related to Low-Level Radioactive Waste (LLW) Disposal" that was held at the USGS National Center Auditorium, Reston, Virginia, May 4-6, 1993. The objective of the workshop was to provide a forum for exchange of information, ideas, and technology in the geosciences dealing with LLW disposal. This workshop was the first joint activity under the Memorandum of Understanding between the USGS and NRC's Office of Nuclear Regulatory Research signed in April 1992.Participants included invited speakers from the USGS, NRC technical contractors (U.S. Department of Energy (DOE) National Laboratories and universities) and NRC staff for presentation of research study results related to LLW disposal. Also in attendance were scientists from the DOE, DOE National Laboratories, the U.S. Environmental Protection Agency, State developmental and regulatory agencies involved in LLW disposal facility siting and licensing, Atomic Energy Canada Limited (AECL), private industry, Agricultural Research Service, universities, USGS and NRC.

  2. Educational Effort in Five Resource Frontier Communities. Center for Settlement Studies, Series 2: Research Report No. 7.

    ERIC Educational Resources Information Center

    Husby, P. J.

    The study examined the educational efforts of five resource frontier communities (Thompson, Flin Flon, Lynn Lake, and Pinawa in Manitoba and Red Lake in Ontario) and compared their educational efforts with that of the Province of Manitoba. The measures of educational effort used were then evaluated to determine whether they might be usefully…

  3. Registration of knee joint surfaces for the in vivo study of joint injuries based on magnetic resonance imaging

    NASA Astrophysics Data System (ADS)

    Cheng, Rita W. T.; Habib, Ayman F.; Frayne, Richard; Ronsky, Janet L.

    2006-03-01

    In-vivo quantitative assessments of joint conditions and health status can help to increase understanding of the pathology of osteoarthritis, a degenerative joint disease that affects a large population each year. Magnetic resonance imaging (MRI) provides a non-invasive and accurate means to assess and monitor joint properties, and has become widely used for diagnosis and biomechanics studies. Quantitative analyses and comparisons of MR datasets require accurate alignment of anatomical structures, thus image registration becomes a necessary procedure for these applications. This research focuses on developing a registration technique for MR knee joint surfaces to allow quantitative study of joint injuries and health status. It introduces a novel idea of translating techniques originally developed for geographic data in the field of photogrammetry and remote sensing to register 3D MR data. The proposed algorithm works with surfaces that are represented by randomly distributed points with no requirement of known correspondences. The algorithm performs matching locally by identifying corresponding surface elements, and solves for the transformation parameters relating the surfaces by minimizing normal distances between them. This technique was used in three applications to: 1) register temporal MR data to verify the feasibility of the algorithm to help monitor diseases, 2) quantify patellar movement with respect to the femur based on the transformation parameters, and 3) quantify changes in contact area locations between the patellar and femoral cartilage at different knee flexion angles. The results indicate accurate registration and the proposed algorithm can be applied for in-vivo study of joint injuries with MRI.

  4. Contribution of Leg-Muscle Forces to Paddle Force and Kayak Speed During Maximal-Effort Flat-Water Paddling.

    PubMed

    Nilsson, Johnny E; Rosdahl, Hans G

    2016-01-01

    The purpose was to investigate the contribution of leg-muscle-generated forces to paddle force and kayak speed during maximal-effort flat-water paddling. Five elite male kayakers at national and international level participated. The participants warmed up at progressively increasing speeds and then performed a maximal-effort, nonrestricted paddling sequence. This was followed after 5 min rest by a maximal-effort paddling sequence with the leg action restricted--the knee joints "locked." Left- and right-side foot-bar and paddle forces were recorded with specially designed force devices. In addition, knee angular displacement of the right and left knees was recorded with electrogoniometric technique, and the kayak speed was calculated from GPS signals sampled at 5 Hz. The results showed that reduction in both push and pull foot-bar forces resulted in a reduction of 21% and 16% in mean paddle-stroke force and mean kayak speed, respectively. Thus, the contribution of foot-bar force from lower-limb action significantly contributes to kayakers' paddling performance.

  5. Motivation and effort in individuals with social anhedonia

    PubMed Central

    McCarthy, Julie M.; Treadway, Michael T.; Blanchard, Jack J.

    2015-01-01

    It has been proposed that anhedonia may, in part, reflect difficulties in reward processing and effortful decision-making. The current study aimed to replicate previous findings of effortful decision-making deficits associated with elevated anhedonia and expand upon these findings by investigating whether these decision-making deficits are specific to elevated social anhedonia or are also associated with elevated positive schizotypy characteristics. The current study compared controls (n = 40) to individuals elevated on social anhedonia (n = 30), and individuals elevated on perceptual aberration/magical ideation (n = 30) on the Effort Expenditure for Rewards Task (EEfRT). Across groups, participants chose a higher proportion of hard tasks with increasing probability of reward and reward magnitude, demonstrating sensitivity to probability and reward values. Contrary to our expectations, when the probability of reward was most uncertain (50% probability), at low and medium reward values, the social anhedonia group demonstrated more effortful decision-making than either individuals high in positive schizotypy or controls. The positive schizotypy group only differed from controls (making less effortful choices than controls) when reward probability was lowest (12%) and the magnitude of reward was the smallest. Our results suggest that social anhedonia is related to intact motivation and effort for monetary rewards, but that individuals with this characteristic display a unique and perhaps inefficient pattern of effort allocation when the probability of reward is most uncertain. Future research is needed to better understand effortful decision-making and the processing of reward across a range of individual difference characteristics. PMID:25888337

  6. Motivation and effort in individuals with social anhedonia.

    PubMed

    McCarthy, Julie M; Treadway, Michael T; Blanchard, Jack J

    2015-06-01

    It has been proposed that anhedonia may, in part, reflect difficulties in reward processing and effortful decision making. The current study aimed to replicate previous findings of effortful decision making deficits associated with elevated anhedonia and expand upon these findings by investigating whether these decision making deficits are specific to elevated social anhedonia or are also associated with elevated positive schizotypy characteristics. The current study compared controls (n=40) to individuals elevated on social anhedonia (n=30), and individuals elevated on perceptual aberration/magical ideation (n=30) on the Effort Expenditure for Rewards Task (EEfRT). Across groups, participants chose a higher proportion of hard tasks with increasing probability of reward and reward magnitude, demonstrating sensitivity to probability and reward values. Contrary to our expectations, when the probability of reward was most uncertain (50% probability), at low and medium reward values, the social anhedonia group demonstrated more effortful decision making than either individuals high in positive schizotypy or controls. The positive schizotypy group only differed from controls (making less effortful choices than controls) when reward probability was lowest (12%) and the magnitude of reward was the smallest. Our results suggest that social anhedonia is related to intact motivation and effort for monetary rewards, but that individuals with this characteristic display a unique and perhaps inefficient pattern of effort allocation when the probability of reward is most uncertain. Future research is needed to better understand effortful decision making and the processing of reward across a range of individual difference characteristics. Copyright © 2015 Elsevier B.V. All rights reserved.

  7. The impact of joint ventures on U.S. hospitals.

    PubMed

    Harrison, Jeffrey P

    2006-01-01

    This quantitative research study assesses the organizational characteristics, market factors, and profitability of US hospitals that operate joint ventures with other health care organizations. Data was obtained from the 2001 American Hospital Association annual survey, the Area Resource File, and the Center for Medicare and Medicaid Services Minimum Data Set. These data files provide essential information on individual acute care hospitals, the communities they serve, and the level of financial performance. Descriptive statistics were evaluated and a logistic regression model was utilized to examine hospitals operating joint ventures. The study found hospitals that operate joint ventures are located in communities with more elderly patients, lower unemployment, and lower HMO penetration. From an operating performance perspective, hospitals that operate joint ventures have a higher occupancy rate, a higher average length of stay, more clinical services, lower long-term debt, and a greater number of managed care contracts. The results also appear to indicate that joint ventures have a positive financial impact on US hospitals. The study has managerial implications supporting the use of joint ventures to improve hospital performance and policy implications on resource allocation.

  8. Changes in balance and joint position sense during a 12-day high altitude trek: The British Services Dhaulagiri medical research expedition.

    PubMed

    Clarke, Sarah B; Deighton, Kevin; Newman, Caroline; Nicholson, Gareth; Gallagher, Liam; Boos, Christopher J; Mellor, Adrian; Woods, David R; O'Hara, John P

    2018-01-01

    Postural control and joint position sense are essential for safely undertaking leisure and professional activities, particularly at high altitude. We tested whether exposure to a 12-day trek with a gradual ascent to high altitude impairs postural control and joint position sense. This was a repeated measures observational study of 12 military service personnel (28±4 years). Postural control (sway velocity measured by a portable force platform) during standing balance, a Sharpened Romberg Test and knee joint position sense were measured, in England (113m elevation) and at 3 research camps (3619m, 4600m and 5140m) on a 12-day high altitude trek in the Dhaulagiri region of Nepal. Pulse oximetry, and Lake Louise scores were also recorded on the morning and evening of each trek day. Data were compared between altitudes and relationships between pulse oximetry, Lake Louise score, and sway velocity were explored. Total sway velocity during standing balance with eyes open (p = 0.003, d = 1.9) and during Sharpened Romberg test with eyes open (p = 0.007, d = 1.6) was significantly greater at altitudes of 3619m and 5140m when compared with sea level. Anterior-posterior sway velocity during standing balance with eyes open was also significantly greater at altitudes of 3619m and 5140m when compared with sea level (p = 0.001, d = 1.9). Knee joint position sense was not altered at higher altitudes. There were no significant correlations between Lake Louise scores, pulse oximetry and postural sway. Despite a gradual ascent profile, exposure to 3619 m was associated with impairments in postural control without impairment in knee joint position sense. Importantly, these impairments did not worsen at higher altitudes of 4600 m or 5140 m. The present findings should be considered during future trekking expeditions when developing training strategies targeted to manage impairments in postural control that occur with increasing altitude.

  9. United States -- Mexican joint ventures: A case history approach

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Moore, N.L.; Chidester, R.J.; Hughes, K.R.

    1993-03-01

    Because the Mexican government has encouraged investment in Mexico by increasing the percentage of ownership of a Mexican business that a US company can hold, joint ventures are more attractive now than they had been in the past. This study provides preliminary information for US renewable energy companies who are interested in forming a joint venture with a Mexican company. This report is not intended to be a complete reference but does identifies a number of important factors that should be observed when forming a Mexican joint venture: (1)Successful joint ventures achieve the goals of each partner. (2)It is essentialmore » that all parties agree to the allocation of responsibilities. (3)Put everything in writing. (4)Research in depth the country or countries in which you are considering doing business.« less

  10. Thoracic costotransverse joint pain patterns: a study in normal volunteers.

    PubMed

    Young, Brian A; Gill, Howard E; Wainner, Robert S; Flynn, Timothy W

    2008-10-15

    Pain referral patterns of asymptomatic costotransverse joints have not been established. The objective of this study was to determine the pain referral patterns of asymptomatic costotransverse joints via provocative intra-articular injection. Eight asymptomatic male volunteers received a combined total of 21 intra-articular costotransverse joint injections. Fluoroscopic imaging was used to identify and isolate each costotransverse joint and guide placement of a 25 gauge, 2.5 inch spinal needle into the costotransverse joint. Following contrast medium injection, the quality, intensity, and distribution of the resultant pain produced were recorded. Of the 21 costotransverse joint injections, 16 (76%) were classified as being intra-articular via arthrograms taken at the time of injection, and 14 of these injections produced a pain sensation distinctly different from that of needle placement. Average pain produced was 3.3/10 on a 0-10 verbal pain scale. Pain was described generally as a deep, dull ache, and pressure sensation. Pain patterns were located superficial to the injected joint, with only the right T2 injections showing referred pain 2 segments cranially and caudally. No chest wall, upper extremity or pseudovisceral pains were reported. This study provides preliminary data of the pain referral patterns of costotransverse joints. Further research is needed to compare these findings with those elicited from symptomatic subjects.

  11. Joint sealant study

    DOT National Transportation Integrated Search

    1987-09-01

    ADOT has approximately 550 lane miles of jointed portland cement pavement under its jurisdiction. The current practice is to saw and seal the joints at the time of construction and reseal the joints under a rehabilitation project. ADOT does not speci...

  12. Dislocation of temporo-mandibular joint - an uncommon circumstance of occurrence: vaginal delivery.

    PubMed

    El Bouazzaoui, Abderrahim; Labib, Smael; Derkaoui, Ali; Adnane Berdai, Mohammed; Bendadi, Azzeddine; Harandou, Mustapha

    2010-06-25

    Dislocation of temporo-mandibular joint (TMJ) is an infrequent disease but still spectacular. This disease consists of a permanent, to some extent complete disruption of the temporo-mandibular joint. These dislocations often occur in a context of yawning, and less frequently after a burst of laughing or relatively mild facial trauma (slap, punch on the chin). We report a case of TMJ occurring in an uncommon circumstance: vaginal delivery. A woman aged 24-years with no special past medical history; primipara was admitted in the Department of Maternity of the University Hospital Hassan II of Fez for an imminent delivery of a twin pregnancy. Ten minutes after admission, the patient delivered vaginally with episiotomy. She gave birth to twins weighing 2800 g and 2400 g. During labour, and due to efforts of crying, the patient developed a sudden and immediate loss of function of the temporo-mandibular joint, with difficulty of speaking, the mouth permanently opened and with the chin lowered and thrown forward. The examination found an empty glenoid fossa of the temporo-mandibular joint in both sides. The diagnosis of dislocation of the TMJ was established. A CT scan of facial bones was done, objectifying a bilateral dislocation of TMJ. The reduction of this dislocation was performed in the operating room under sedation.

  13. VIIRS validation and algorithm development efforts in coastal and inland Waters

    NASA Astrophysics Data System (ADS)

    Stengel, E.; Ondrusek, M.

    2016-02-01

    Accurate satellite ocean color measurements in coastal and inland waters are more challenging than open-ocean measurements. Complex water and atmospheric conditions can limit the utilization of remote sensing data in coastal waters where it is most needed. The Coastal Optical Characterization Experiment (COCE) is an ongoing project at NOAA/NESDIS/STAR Satellite Oceanography and Climatology Division. The primary goals of COCE are satellite ocean color validation and application development. Currently, this effort concentrates on the initialization and validation of the Joint Polar Satellite System (JPSS) VIIRS sensor using a Satlantic HyperPro II radiometer as a validation tool. A report on VIIRS performance in coastal waters will be given by presenting comparisons between in situ ground truth measurements and VIIRS retrievals made in the Chesapeake Bay, and inland waters of the Gulf of Mexico and Puerto Rico. The COCE application development effort focuses on developing new ocean color satellite remote sensing tools for monitoring relevant coastal ocean parameters. A new VIIRS total suspended matter algorithm will be presented for the Chesapeake Bay. These activities improve the utility of ocean color satellite data in monitoring and analyzing coastal and oceanic processes. Progress on these activities will be reported.

  14. Re-Creation of Historical Chrysotile-Containing Joint Compounds

    PubMed Central

    Brorby, G. P.; Sheehan, P. J.; Berman, D. W.; Greene, J. F.; Holm, S. E.

    2008-01-01

    Chrysotile-containing joint compound was commonly used in construction of residential and commercial buildings through the mid 1970s; however, these products have not been manufactured in the United States for more than 30 years. Little is known about actual human exposures to chrysotile fibers that may have resulted from use of chrysotile-containing joint compounds, because few exposure and no health-effects studies have been conducted specifically with these products. Because limited amounts of historical joint compounds are available (and the stability or representativeness of aged products is suspect), it is currently impossible to conduct meaningful studies to better understand the nature and magnitude of potential exposures to chrysotile that may have been associated with historical use of these products. Therefore, to support specific exposure and toxicology research activities, two types of chrysotile-containing joint compounds were produced according to original formulations from the late 1960s. To the extent possible, ingredients were the same as those used originally, with many obtained from the original suppliers. The chrysotile used historically in these products was primarily Grade 7RF9 from the Philip Carey mine. Because this mine is closed, a suitable alternate was identified by comparing the sizes and mineral composition of asbestos structures in a sample of what has been represented to be historical joint compound (all of which were chrysotile) to those in samples of three currently commercially available Grade 7 chrysotile products. The re-created materials generally conformed to original product specifications (e.g. viscosity, workability, crack resistance), indicating that these materials are sufficiently representative of the original products to support research activities. PMID:18788019

  15. Joint awareness in osteoarthritis of the hip and knee evaluated with the 'Forgotten Joint' Score before and after joint replacement.

    PubMed

    Thienpont, E; Vanden Berghe, A; Schwab, P E; Forthomme, J P; Cornu, O

    2016-10-01

    To utilize the 'Forgotten Joint' Score (FJS), a 12-item questionnaire analysing the ability to forget the joint, for comparing preoperative status in osteoarthritic patients scheduled for total hip arthroplasty (THA) or total knee arthroplasty (TKA). Higher scores represent a better result with a maximum of 100. The hypothesis of this study was that a preoperative difference in favour of hip arthritis could eventually explain why THA is cited more often as a forgotten joint than TKA. A prospective cohort study was conducted in 150 patients with either tricompartmental knee (n = 75) or hip osteoarthritis (n = 75). Patients completed FJS-12 scores preoperatively and 1 year postoperatively. A similar preoperative FJS-12 was observed for hip (22 (15)) and knee osteoarthritis (24 (17)) (n.s.). The postoperative FJS-12 score was significantly higher for THA (80 (24)) than for TKA (70 (27)) (p < 0.05). High reliability after 6 weeks was observed for the preoperative FJS-12 test-retest reliability (ICC = 0.87) in TKA. A preoperative floor effect of 15 % in THA and 0 % in TKA was found as well as a postoperative ceiling effect of 33 % in THA and 9 % in TKA. The clinical relevance of utilizing the FJS-12 as an instrument to evaluate outcome is strongly proposed for knee arthroplasty. In general, one is not aware of a healthy joint during the ADL, and it can therefore be regarded as 'forgotten'. The preoperative FJS-12 Score is a powerful tool to provide patients with clearer insights into their positive evolution after surgery. The use of the FJS-12 in THA is a topic for further research, as this study found that floor and ceiling effects limit its usefulness in studies evaluating clinical outcome in this area. II.

  16. Evaluation of joint sealant materials : final report.

    DOT National Transportation Integrated Search

    1977-05-01

    In May, 1968, the Department's Research and Development Section initiated a project to evaluate joint sealants being marketed for use on roads and bridges. In the study, representatives of 31 companies installed 40 products primarily on one road and ...

  17. Fabrication and Assembly of High-Precision Hinge and Latch Joints for Deployable Optical Instruments

    NASA Technical Reports Server (NTRS)

    Phelps, James E.

    1999-01-01

    Descriptions are presented of high-precision hinge and latch joints that have been co-developed, for application to deployable optical instruments, by NASA Langley Research Center and Nyma/ADF. Page-sized versions of engineering drawings are included in two appendices to describe all mechanical components of both joints. Procedures for assembling the mechanical components of both joints are also presented. The information herein is intended to facilitate the fabrication and assembly of the high-precision hinge and latch joints, and enable the incorporation of these joints into the design of deployable optical instrument systems.

  18. Tribological characterization of the drill pipe tool joints reconditioned by using welding technologies

    NASA Astrophysics Data System (ADS)

    Caltaru, M.; Badicioiu, M.; Ripeanu, R. G.; Dinita, A.; Minescu, M.; Laudacescu, E.

    2018-01-01

    Drill pipe is a seamless steel pipe with upset ends fitted with special threaded ends that are known as tool joints. During drilling operations, the wall thickness of the drill pipe and the outside diameter of the tool joints will be gradually reduced due to wear. The present research work investigate the possibility of reconditioning the drill pipe tool joints by hardbanding with a new metal-cored coppered flux cored wire, Cr-Mo alloyed, using the gas metal active welding process, taking into considerations two different hardbanding technologies, consisting in: hardbanding drill pipe tool joints after removing the old hardbanding material and surface reconstruction with a compensation material (case A), and hardbanding tool joint drill pipe, without removing the old hardbanding material (case B). The present paper brings forward the experimental researches regarding the tribological characterization of the reconditioned drill pipe tool joint by performing macroscopic analyses, metallographic analyses, Vickers hardness measurement, chemical composition measurement and wear tests conducted on ball on disk friction couples, in order to certify the quality of the hardbanding obtained by different technological approaches, to validate the optimum technology.

  19. Effect of social influence on effort-allocation for monetary rewards.

    PubMed

    Gilman, Jodi M; Treadway, Michael T; Curran, Max T; Calderon, Vanessa; Evins, A Eden

    2015-01-01

    Though decades of research have shown that people are highly influenced by peers, few studies have directly assessed how the value of social conformity is weighed against other types of costs and benefits. Using an effort-based decision-making paradigm with a novel social influence manipulation, we measured how social influence affected individuals' decisions to allocate effort for monetary rewards during trials with either high or low probability of receiving a reward. We found that information about the effort-allocation of peers modulated participant choices, specifically during conditions of low probability of obtaining a reward. This suggests that peer influence affects effort-based choices to obtain rewards especially under conditions of risk. This study provides evidence that people value social conformity in addition to other costs and benefits when allocating effort, and suggests that neuroeconomic studies that assess trade-offs between effort and reward should consider social environment as a factor that can influence decision-making.

  20. Building an International Geosciences Network (i-GEON) for cyberinfrastructure-based Research and Education

    NASA Astrophysics Data System (ADS)

    Seber, D.; Baru, C.

    2007-05-01

    The Geosciences Network (GEON) project is a collaboration among multiple institutions to develop a cyberinfrastructure (CI) platform in support of integrative geoscience research activities. Taking advantage of the state-of-the-art information technology resources GEON researchers are building a cyberinfrastructure designed to enable data sharing, resource discovery, semantic data integration, high-end computations and 4D visualization in an easy-to-use web-based environment. The cyberinfrastructure in GEON is required to support an inherently distributed system, since the scientists, who are users as well as providers of resources, are themselves distributed. International collaborations are a natural extension of GEON; the geoscience research requires strong international collaborations. The goals of the i-GEON activities are to collaborate with international partners and jointly build a cyberinfrastructure for the geosciences to enable collaborative work environments. International partners can participate in GEON efforts, establish GEON nodes at their universities, institutes, or agencies and also contribute data and tools to the network. Via jointly run cyberinfrastructure workshops, the GEON team also introduces students, scientists, and research professionals to the concepts of IT-based geoscience research and education. Currently, joint activities are underway with the Chinese Academy of Sciences in China, the GEO Grid project at AIST in Japan, and the University of Hyderabad in India (where the activity is funded by the Indo-US Science and Technology Forum). Several other potential international partnerships are under consideration. iGEON is open to all international partners who are interested in working towards the goal of data sharing, managing and integration via IT-based platforms. Information about GEON and its international activities can be found at http:www.geongrid.org/

  1. Joint modelling rationale for chained equations

    PubMed Central

    2014-01-01

    Background Chained equations imputation is widely used in medical research. It uses a set of conditional models, so is more flexible than joint modelling imputation for the imputation of different types of variables (e.g. binary, ordinal or unordered categorical). However, chained equations imputation does not correspond to drawing from a joint distribution when the conditional models are incompatible. Concurrently with our work, other authors have shown the equivalence of the two imputation methods in finite samples. Methods Taking a different approach, we prove, in finite samples, sufficient conditions for chained equations and joint modelling to yield imputations from the same predictive distribution. Further, we apply this proof in four specific cases and conduct a simulation study which explores the consequences when the conditional models are compatible but the conditions otherwise are not satisfied. Results We provide an additional “non-informative margins” condition which, together with compatibility, is sufficient. We show that the non-informative margins condition is not satisfied, despite compatible conditional models, in a situation as simple as two continuous variables and one binary variable. Our simulation study demonstrates that as a consequence of this violation order effects can occur; that is, systematic differences depending upon the ordering of the variables in the chained equations algorithm. However, the order effects appear to be small, especially when associations between variables are weak. Conclusions Since chained equations is typically used in medical research for datasets with different types of variables, researchers must be aware that order effects are likely to be ubiquitous, but our results suggest they may be small enough to be negligible. PMID:24559129

  2. Crafting continuity and change in Saudi society: Joint parent-youth transition-to-adulthood projects.

    PubMed

    Khalifa, Hind; Alnuaim, Aziza A; Young, Richard A; Marshall, Sheila K; Popadiuk, Natalee

    2018-02-01

    Little is known about the transition to adulthood in traditional, developing countries such as Saudi Arabia. Previous research in other countries has revealed the importance of considering parents' support during the transition to adulthood. Thus, the purpose of this research was to examine how two generations negotiated the transition to adulthood. We asked the research question, What are the joint projects in which parents and youth plan and act on their plans for the youth's future? We used the action project method, an established qualitative approach, to answer these questions by observing the joint conversations of 14 parent and youth dyads. Our results provided evidence of an overarching higher level goal, or intentional framework, of crafting generational change and continuity within which participants' joint projects were embedded. Joint projects were organized into three groups: (a) negotiating educational and career futures, (b) promoting gender roles and marriage, and (c) shaping independence. Copyright © 2017 The Foundation for Professionals in Services for Adolescents. All rights reserved.

  3. 7 CFR 3405.7 - Joint project proposals.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Agriculture Regulations of the Department of Agriculture (Continued) COOPERATIVE STATE RESEARCH, EDUCATION, AND EXTENSION SERVICE, DEPARTMENT OF AGRICULTURE HIGHER EDUCATION CHALLENGE GRANTS PROGRAM Program... strengthening higher education in the food and agricultural sciences. The goals of such joint initiatives should...

  4. Faculty and Student Teams and National Laboratories: Expanding the Reach of Research Opportunities and Workforce Development

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Blackburn,N.; White, K.; Stegman, M.

    The Faculty and Student Teams (FaST) Program, a cooperative effort between the US Department of Energy (DOE) Office of Science and the National Science Foundation (NSF), brings together collaborative research teams composed of a researcher at Brookhaven National Laboratory, and a faculty member with two or three undergraduate students from a college or university. Begun by the Department of Energy in 2000 with the primary goal of building research capacity at a faculty member's home institution, the FaST Program focuses its recruiting efforts on faculty from colleges and universities with limited research facilities and those institutions that serve populations under-representedmore » in the fields of science, engineering and technology, particularly women and minorities. Once assembled, a FaST team spends a summer engaged in hands-on research working alongside a laboratory scientist. This intensely collaborative environment fosters sustainable relationships between the faulty members and BNL that allow faculty members and their BNL colleagues to submit joint proposals to federal agencies, publish papers in peer-reviewed journals, reform local curriculum, and develop new or expand existing research labs at their home institutions.« less

  5. Robotic Joints Support Horses and Humans

    NASA Technical Reports Server (NTRS)

    2008-01-01

    A rehabilitative device first featured in Spinoff 2003 is not only helping human patients regain the ability to walk, but is now helping our four-legged friends as well. The late James Kerley, a prominent Goddard Space Flight Center researcher, developed cable-compliant mechanisms in the 1980s to enable sounding rocket assemblies and robots to grip or join objects. In cable-compliant joints (CCJs), short segments of cable connect structural elements, allowing for six directions of movement, twisting, alignment, and energy damping. Kerley later worked with Goddard s Wayne Eklund and Allen Crane to incorporate the cable-compliant mechanisms into a walker for human patients to support the pelvis and imitate hip joint movement.

  6. Joint swelling

    MedlinePlus

    ... of arthritis caused by buildup of uric acid crystals in a joint ( gout ) Arthritis caused by wear ... osteoarthritis ) Arthritis caused by buildup of calcium-type crystals in joints ( pseudogout ) Disorder that involves arthritis and ...

  7. Generalized Cross Entropy Method for estimating joint distribution from incomplete information

    NASA Astrophysics Data System (ADS)

    Xu, Hai-Yan; Kuo, Shyh-Hao; Li, Guoqi; Legara, Erika Fille T.; Zhao, Daxuan; Monterola, Christopher P.

    2016-07-01

    Obtaining a full joint distribution from individual marginal distributions with incomplete information is a non-trivial task that continues to challenge researchers from various domains including economics, demography, and statistics. In this work, we develop a new methodology referred to as ;Generalized Cross Entropy Method; (GCEM) that is aimed at addressing the issue. The objective function is proposed to be a weighted sum of divergences between joint distributions and various references. We show that the solution of the GCEM is unique and global optimal. Furthermore, we illustrate the applicability and validity of the method by utilizing it to recover the joint distribution of a household profile of a given administrative region. In particular, we estimate the joint distribution of the household size, household dwelling type, and household home ownership in Singapore. Results show a high-accuracy estimation of the full joint distribution of the household profile under study. Finally, the impact of constraints and weight on the estimation of joint distribution is explored.

  8. A Modelling Method of Bolt Joints Based on Basic Characteristic Parameters of Joint Surfaces

    NASA Astrophysics Data System (ADS)

    Yuansheng, Li; Guangpeng, Zhang; Zhen, Zhang; Ping, Wang

    2018-02-01

    Bolt joints are common in machine tools and have a direct impact on the overall performance of the tools. Therefore, the understanding of bolt joint characteristics is essential for improving machine design and assembly. Firstly, According to the experimental data obtained from the experiment, the stiffness curve formula was fitted. Secondly, a finite element model of unit bolt joints such as bolt flange joints, bolt head joints, and thread joints was constructed, and lastly the stiffness parameters of joint surfaces were implemented in the model by the secondary development of ABAQUS. The finite element model of the bolt joint established by this method can simulate the contact state very well.

  9. The road to heaven is paved with effort: Perceived effort amplifies moral judgment.

    PubMed

    Bigman, Yochanan E; Tamir, Maya

    2016-12-01

    If good intentions pave the road to hell, what paves the road to heaven? We propose that moral judgments are based, in part, on the degree of effort exerted in performing the immoral or moral act. Because effort can serve as an index of goal importance, greater effort in performing immoral acts would lead to more negative judgments, whereas greater effort in performing moral acts would lead to more positive judgments. In support of these ideas, we found that perceived effort intensified judgments of both immoral (Studies 1-2) and moral (Studies 2-7) agents. The effect of effort on judgment was independent of the outcome (Study 3) and of perceptions of the outcome extremity (Study 6). Furthermore, the effect of effort on judgment was mediated by perceived goal importance (Studies 4-6), even when controlling for perceived intentions (Studies 5-6). Finally, we demonstrate that perceived effort can influence actual behavior, such as the assignment of monetary rewards (Study 7). We discuss the possible implications of effort as a causal motivational factor in moral judgment and social retribution. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  10. Joint replacement recipients' views about health information privacy.

    PubMed

    Terry, Amanda L; Chesworth, Bert M; Bourne, Robert B; Stolee, Paul; Speechley, Mark

    2015-10-01

    Researchers are concerned about the possibility of restricted access to data as a result of specific consent requirements in privacy legislation, potentially resulting in smaller samples and a lack of representativeness which could bias results. In addition, there is uncertainty about what influences individuals to give consent for the use of their personal health information. To measure joint replacement recipients' health information privacy views and to assess potential predictors of these views. Cross-sectional survey. Potential joint replacement recipients from two teaching hospitals in London, Ontario, Canada. Age, gender, education, employment status, anticipated joint replacement, and expectations for surgery. Privacy concerns as measured by the Concern Scale. The response rate was 182/253 or 72%. The mean Concern score was 143.9/235.0 for the total sample (range = 82-216). Women had higher levels of privacy concerns than men on slightly over half of the individual questionnaire items. In women, surgical joint, age and employment explained 15% of the variance in concerns about personal health information privacy (P = 0.001). The model explained 6% of the variance in concerns in men (P = 0.138) and was not statistically significant. This study indicates that demographic characteristics and health-care experiences play a role in the variability of health information privacy concerns. A greater understanding of patients' privacy views about health information could lead to a greater harmonization among privacy rules, research and data access, and the preferences of health-care consumers. © 2013 John Wiley & Sons Ltd.

  11. Mutual coordination strengthens the sense of joint agency in cooperative joint action.

    PubMed

    Bolt, Nicole K; Poncelet, Evan M; Schultz, Benjamin G; Loehr, Janeen D

    2016-11-01

    Philosophers have proposed that when people coordinate their actions with others they may experience a sense of joint agency, or shared control over actions and their effects. However, little empirical work has investigated the sense of joint agency. In the current study, pairs coordinated their actions to produce tone sequences and then rated their sense of joint agency on a scale ranging from shared to independent control. People felt more shared than independent control overall, confirming that people experience joint agency during joint action. Furthermore, people felt stronger joint agency when they (a) produced sequences that required mutual coordination compared to sequences in which only one partner had to coordinate with the other, (b) held the role of follower compared to leader, and (c) were better coordinated with their partner. Thus, the strength of joint agency is influenced by the degree to which people mutually coordinate with each other's actions. Copyright © 2016 Elsevier Inc. All rights reserved.

  12. Perspectives Do Matter: "Joint Screen", a Promising Methodology for Multimodal Interaction Analysis

    ERIC Educational Resources Information Center

    Arend, Béatrice; Sunnen, Patrick; Fixmer, Pierre; Sujbert, Monika

    2014-01-01

    This paper discusses theoretical and methodological issues arising from a video-based research design and the emergent tool "Joint Screen'"when grasping joint activity. We share our reflections regarding the combined reading of four synchronised camera perspectives combined in one screen. By these means we reconstruct and analyse…

  13. Copula Models for Sociology: Measures of Dependence and Probabilities for Joint Distributions

    ERIC Educational Resources Information Center

    Vuolo, Mike

    2017-01-01

    Often in sociology, researchers are confronted with nonnormal variables whose joint distribution they wish to explore. Yet, assumptions of common measures of dependence can fail or estimating such dependence is computationally intensive. This article presents the copula method for modeling the joint distribution of two random variables, including…

  14. Joint Chiefs of Staff > Leadership

    Science.gov Websites

    Senior Enlisted Advisor Joint Staff History Joint Staff Inspector General Joint Staff Structure Origin of J8 | Force Structure, Resources & Assessment Contact Joint Staff Structure Joint Staff Organizational Chart Joint Chiefs of Staff Links Home Today in DOD About DOD Top Issues News Photos/Videos

  15. POEM: Identifying Joint Additive Effects on Regulatory Circuits

    PubMed Central

    Botzman, Maya; Nachshon, Aharon; Brodt, Avital; Gat-Viks, Irit

    2016-01-01

    Motivation: Expression Quantitative Trait Locus (eQTL) mapping tackles the problem of identifying variation in DNA sequence that have an effect on the transcriptional regulatory network. Major computational efforts are aimed at characterizing the joint effects of several eQTLs acting in concert to govern the expression of the same genes. Yet, progress toward a comprehensive prediction of such joint effects is limited. For example, existing eQTL methods commonly discover interacting loci affecting the expression levels of a module of co-regulated genes. Such “modularization” approaches, however, are focused on epistatic relations and thus have limited utility for the case of additive (non-epistatic) effects. Results: Here we present POEM (Pairwise effect On Expression Modules), a methodology for identifying pairwise eQTL effects on gene modules. POEM is specifically designed to achieve high performance in the case of additive joint effects. We applied POEM to transcription profiles measured in bone marrow-derived dendritic cells across a population of genotyped mice. Our study reveals widespread additive, trans-acting pairwise effects on gene modules, characterizes their organizational principles, and highlights high-order interconnections between modules within the immune signaling network. These analyses elucidate the central role of additive pairwise effect in regulatory circuits, and provide computational tools for future investigations into the interplay between eQTLs. Availability: The software described in this article is available at csgi.tau.ac.il/POEM/. PMID:27148351

  16. Joint Attention, Social-Cognition, and Recognition Memory in Adults

    PubMed Central

    Kim, Kwanguk; Mundy, Peter

    2012-01-01

    The early emerging capacity for Joint Attention (JA), or socially coordinated visual attention, is thought to be integral to the development of social-cognition in childhood. Recent studies have also begun to suggest that JA affects adult cognition as well, but methodological limitations hamper research on this topic. To address this issue we developed a novel virtual reality paradigm that integrates eye-tracking and virtual avatar technology to measure two types of JA in adults, Initiating Joint Attention (IJA) and Responding to Joint Attention (RJA). Distinguishing these types of JA in research is important because they are thought to reflect unique, as well as common constellations of processes involved in human social-cognition and social learning. We tested the validity of the differentiation of IJA and RJA in our paradigm in two studies of picture recognition memory in undergraduate students. Study 1 indicated that young adults correctly identified more pictures they had previously viewed in an IJA condition (67%) than in a RJA (58%) condition, η2 = 0.57. Study 2 controlled for IJA and RJA stimulus viewing time differences, and replicated the findings of Study 1. The implications of these results for the validity of the paradigm and research on the affects of JA on adult social-cognition are discussed. PMID:22712011

  17. Smart campus transit laboratory for research and education.

    DOT National Transportation Integrated Search

    2011-12-31

    A joint effort by the Ohio State University (OSU) Transportation and Parking Services, OSU College of Engineering, OSU Department of Civil and Environmental Engineering and Geodetic Science, and Clever Devices has recently succeeded in equipping the ...

  18. Comparison of tibiofemoral joint space width measurements from standing CT and fixed flexion radiography.

    PubMed

    Segal, Neil A; Frick, Eric; Duryea, Jeffrey; Nevitt, Michael C; Niu, Jingbo; Torner, James C; Felson, David T; Anderson, Donald D

    2017-07-01

    The objective of this project was to determine the relationship between medial tibiofemoral joint space width measured on fixed-flexion radiographs and the three-dimensional joint space width distribution on low-dose, standing CT (SCT) imaging. At the 84-month visit of the Multicenter Osteoarthritis Study, 20 participants were recruited. A commercial SCT scanner for the foot and ankle was modified to image knees while standing. Medial tibiofemoral joint space width was assessed on radiographs at fixed locations from 15% to 30% of compartment width using validated software and on SCT by mapping the distances between three-dimensional subchondral bone surfaces. Individual joint space width values from radiographs were compared with three-dimensional joint space width values from corresponding sagittal plane locations using paired t-tests and correlation coefficients. For the four medial-most tibiofemoral locations, radiographic joint space width values exceeded the minimal joint space width on SCT by a mean of 2.0 mm and were approximately equal to the 61st percentile value of the joint space width distribution at each respective sagittal-plane location. Correlation coefficients at these locations were 0.91-0.97 and the offsets between joint space width values from radiographs and SCT measurements were consistent. There were greater offsets and variability in the offsets between modalities closer to the tibial spine. Joint space width measurements on fixed-flexion radiographs are highly correlated with three-dimensional joint space width from SCT. In addition to avoiding bony overlap obscuring the joint, a limitation of radiographs, the current study supports a role for SCT in the evaluation of tibiofemoral OA. © 2017 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 35:1388-1395, 2017. © 2017 Orthopaedic Research Society. Published by Wiley Periodicals, Inc.

  19. A universal six-joint robot controller

    NASA Technical Reports Server (NTRS)

    Bihn, D. G.; Hsia, T. C.

    1987-01-01

    A general purpose six-axis robotic manipulator controller was designed and implemented to serve as a research tool for the investigation of the practical and theoretical aspects of various control strategies in robotics. A 80286-based Intel System 310 running the Xenix operating servo software as well as the higher level software (e.g., kinematics and path planning) were employed. A Multibus compatible interface board was designed and constructed to handle I/O signals from the robot manipulator's joint motors. From the design point of view, the universal controller is capable of driving robot manipulators equipped with D.C. joint motors and position optical encoders. To test its functionality, the controller is connected to the joint motor D.C. power amplifier of a PUMA 560 arm bypassing completely the manufacturer-supplied Unimation controller. A controller algorithm consisting of local PD control laws was written and installed into the Xenix operating system. Additional software drivers were implemented to allow application programs access to the interface board. All software was written in the C language.

  20. Signaling networks in joint development

    PubMed Central

    Salva, Joanna E.; Merrill, Amy E.

    2016-01-01

    Here we review studies identifying regulatory networks responsible for synovial, cartilaginous, and fibrous joint development. Synovial joints, characterized by the fluid-filled synovial space between the bones, are found in high-mobility regions and are the most common type of joint. Cartilaginous joints unite adjacent bones through either a hyaline cartilage or fibrocartilage intermediate. Fibrous joints, which include the cranial sutures, form a direct union between bones through fibrous connective tissue. We describe how the distinct morphologic and histogenic characteristics of these joint classes are established during embryonic development. Collectively, these studies reveal that despite the heterogeneity of joint strength and mobility, joint development throughout the skeleton utilizes common signaling networks via long-range morphogen gradients and direct cell-cell contact. This suggests that different joint types represent specialized variants of homologous developmental modules. Identifying the unifying aspects of the signaling networks between joint classes allows a more complete understanding of the signaling code for joint formation, which is critical to improving strategies for joint regeneration and repair. PMID:27859991

  1. DARPA-funded efforts in the development of novel brain-computer interface technologies.

    PubMed

    Miranda, Robbin A; Casebeer, William D; Hein, Amy M; Judy, Jack W; Krotkov, Eric P; Laabs, Tracy L; Manzo, Justin E; Pankratz, Kent G; Pratt, Gill A; Sanchez, Justin C; Weber, Douglas J; Wheeler, Tracey L; Ling, Geoffrey S F

    2015-04-15

    The Defense Advanced Research Projects Agency (DARPA) has funded innovative scientific research and technology developments in the field of brain-computer interfaces (BCI) since the 1970s. This review highlights some of DARPA's major advances in the field of BCI, particularly those made in recent years. Two broad categories of DARPA programs are presented with respect to the ultimate goals of supporting the nation's warfighters: (1) BCI efforts aimed at restoring neural and/or behavioral function, and (2) BCI efforts aimed at improving human training and performance. The programs discussed are synergistic and complementary to one another, and, moreover, promote interdisciplinary collaborations among researchers, engineers, and clinicians. Finally, this review includes a summary of some of the remaining challenges for the field of BCI, as well as the goals of new DARPA efforts in this domain. Copyright © 2014 The Authors. Published by Elsevier B.V. All rights reserved.

  2. Joint venture schemes in Limpopo Province and their outcomes on smallholder farmers livelihoods

    NASA Astrophysics Data System (ADS)

    Mapedza, Everisto; van Koppen, Barbara; Sithole, Pinimidzai; Bourblanc, Magalie

    2016-04-01

    Joint Venture schemes based on the floppy irrigation technology are being promoted in the post-Apartheid South Africa's Limpopo Province. Access to land and water resources in South Africa are largely viewed as a mechanism for re-dressing the Apartheid injustices. This research was part of a broader applied research to help inform irrigation practise in the Limpopo Province. The research used literature review, key informant interviews and a questionnaire survey. The overall research question sought to understand how the Joint Venture Schemes had benefited the smallholder farmers. This paper argues that the joint venture partnership created a new injustice. Firstly, the Joint Venture Scheme design is fundamentally a bad idea which disempower farmers not only to water access but also land as well. The choice of the 'efficient' floppy irrigation technology was made by the state and entailed that land had to be managed as a single unit. In order to make more effective use of this highly sophisticated new technology, the smallholder farmers also needed to go into a joint venture partnership with a white commercial farmer. By virtue of signing the Joint Venture agreement the farmers were also forfeiting their land and water rights to be used for crop production. The smallholder farmers lost access to their water and land resources and were largely relegated to sharing profits - when they exist - with hardly any skills development despite what was initially envisaged in the Joint Venture partnership. Secondly, the implementation of the JVS has been skewed from the start which explains the bad results. This paper further shows how the negative outcomes affected women in particular. As the smallholder farmers argue the technological options chosen by the state have excluded both male and female farmers from accessing and utilising their land and water resources in order to improve their livelihoods; it has entrenched the role of the state and the private interests at the

  3. Estimation of ground reaction forces and joint moments on the basis on plantar pressure insoles and wearable sensors for joint angle measurement.

    PubMed

    Ostaszewski, Michal; Pauk, Jolanta

    2018-05-16

    Gait analysis is a useful tool medical staff use to support clinical decision making. There is still an urgent need to develop low-cost and unobtrusive mobile health monitoring systems. The goal of this study was twofold. Firstly, a wearable sensor system composed of plantar pressure insoles and wearable sensors for joint angle measurement was developed. Secondly, the accuracy of the system in the measurement of ground reaction forces and joint moments was examined. The measurements included joint angles and plantar pressure distribution. To validate the wearable sensor system and examine the effectiveness of the proposed method for gait analysis, an experimental study on ten volunteer subjects was conducted. The accuracy of measurement of ground reaction forces and joint moments was validated against the results obtained from a reference motion capture system. Ground reaction forces and joint moments measured by the wearable sensor system showed a root mean square error of 1% for min. GRF and 27.3% for knee extension moment. The correlation coefficient was over 0.9, in comparison with the stationary motion capture system. The study suggests that the wearable sensor system could be recommended both for research and clinical applications outside a typical gait laboratory.

  4. On the apparent insignificance of the randomness of flexible joints on large space truss dynamics

    NASA Technical Reports Server (NTRS)

    Koch, R. M.; Klosner, J. M.

    1993-01-01

    Deployable periodic large space structures have been shown to exhibit high dynamic sensitivity to period-breaking imperfections and uncertainties. These can be brought on by manufacturing or assembly errors, structural imperfections, as well as nonlinear and/or nonconservative joint behavior. In addition, the necessity of precise pointing and position capability can require the consideration of these usually negligible and unknown parametric uncertainties and their effect on the overall dynamic response of large space structures. This work describes the use of a new design approach for the global dynamic solution of beam-like periodic space structures possessing parametric uncertainties. Specifically, the effect of random flexible joints on the free vibrations of simply-supported periodic large space trusses is considered. The formulation is a hybrid approach in terms of an extended Timoshenko beam continuum model, Monte Carlo simulation scheme, and first-order perturbation methods. The mean and mean-square response statistics for a variety of free random vibration problems are derived for various input random joint stiffness probability distributions. The results of this effort show that, although joint flexibility has a substantial effect on the modal dynamic response of periodic large space trusses, the effect of any reasonable uncertainty or randomness associated with these joint flexibilities is insignificant.

  5. A computational framework for simultaneous estimation of muscle and joint contact forces and body motion using optimization and surrogate modeling.

    PubMed

    Eskinazi, Ilan; Fregly, Benjamin J

    2018-04-01

    Concurrent estimation of muscle activations, joint contact forces, and joint kinematics by means of gradient-based optimization of musculoskeletal models is hindered by computationally expensive and non-smooth joint contact and muscle wrapping algorithms. We present a framework that simultaneously speeds up computation and removes sources of non-smoothness from muscle force optimizations using a combination of parallelization and surrogate modeling, with special emphasis on a novel method for modeling joint contact as a surrogate model of a static analysis. The approach allows one to efficiently introduce elastic joint contact models within static and dynamic optimizations of human motion. We demonstrate the approach by performing two optimizations, one static and one dynamic, using a pelvis-leg musculoskeletal model undergoing a gait cycle. We observed convergence on the order of seconds for a static optimization time frame and on the order of minutes for an entire dynamic optimization. The presented framework may facilitate model-based efforts to predict how planned surgical or rehabilitation interventions will affect post-treatment joint and muscle function. Copyright © 2018 IPEM. Published by Elsevier Ltd. All rights reserved.

  6. Student Effort in and Perceived Benefits from Undergraduate Research

    ERIC Educational Resources Information Center

    Salsman, Nicholas; Dulaney, Cynthia L.; Chinta, Ravi; Zascavage, Victoria; Joshi, Hem

    2013-01-01

    The benefits of student engagement in undergraduate research are well-recognized by many higher education institutions. Increased emphasis on undergraduate research in these institutions has taken many forms resulting in considerable differences across institutions ranging from "light touch" to "heavy duty" involvement of…

  7. Cryotherapy does not impair shoulder joint position sense.

    PubMed

    Dover, Geoffrey; Powers, Michael E

    2004-08-01

    To determine the effects of a cryotherapy treatment on shoulder proprioception. Crossover design with repeated measures. University athletic training and sports medicine research laboratory. Thirty healthy subjects (15 women, 15 men). A 30-minute cryotherapy treatment. Joint position sense was measured in the dominant shoulder by using an inclinometer before and after receiving 30 minutes of either no ice or a 1-kg ice bag application. Skin temperature was measured below the tip of the acromion process and recorded every 5 minutes for the entire 30 minutes and immediately after testing. Three different types of error scores were calculated for data analyses and used to determine proprioception. Separate analyses of absolute, constant, and variable error failed to identify changes in shoulder joint proprioception as a function of the cryotherapy application. Application of an ice bag to the shoulder does not impair joint position sense. The control of proprioception at the shoulder may be more complex than at other joints in the body. Clinical implications may involve modifying rehabilitation considerations when managing shoulder injuries.

  8. A Revolute Joint With Linear Load-Displacement Response for Precision Deployable Structures

    NASA Technical Reports Server (NTRS)

    Lake, Mark S.; Warren, Peter A.; Peterson, Lee D.

    1996-01-01

    NASA Langley Research center is developing key structures and mechanisms technologies for micron-accuracy, in-space deployment of future space instruments. Achieving micron-accuracy deployment requires significant advancements in deployment mechanism design such as the revolute joint presented herein. The joint presented herein exhibits a load-cycling response that is essentially linear with less than two percent hysteresis, and the joint rotates with less than one in.-oz. of resistance. A prototype reflector metering truss incorporating the joint exhibits only a few microns of kinematic error under repeated deployment and impulse loading. No other mechanically deployable structure found in literature has been demonstrated to be this kinematically accurate.

  9. Prologue: 2017 Annual Meeting of the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA).

    PubMed

    Helliwell, Philip S; Gladman, Dafna D; Gottlieb, Alice B

    2018-06-01

    The 2017 Annual Meeting of the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) was held in Amsterdam, the Netherlands, and was attended by rheumatologists, dermatologists, representatives of biopharmaceutical companies, and patients. As in previous years, GRAPPA members held a symposium for trainees to discuss their research in psoriatic disease with experts in the field. Other subjects featured during the annual meeting included a discussion of the history, clinical features, controversies, and immunogenetics of juvenile psoriatic arthritis; updates from working groups in Outcome Measures in Rheumatology and International Dermatology Outcome Measures; a discussion of the benefits and challenges of setting up a longitudinal psoriatic arthritis (PsA) database; 3 separate discussions of the effects of the microbiome on skin and joints in psoriasis and PsA; a discussion of options for assessing joints and entheses in PsA by ultrasonography and magnetic resonance imaging; an update on GRAPPA's research and educational projects; a discussion of patient centricity, including the incorporation of patient research partners (PRP) into psoriasis and PsA research and educational efforts, from GRAPPA's PRP; and a discussion of the GRAPPA-Collaborative Research Network's inaugural meeting. In this prologue, we introduce the papers that summarize that meeting.

  10. Understanding and Controlling Cost in Total Joint Arthroplasty.

    PubMed

    Alvarado, Carlos M; Bosco, Joseph

    2015-06-01

    Total joint arthrosplasty (TJA) is both a commonly performed successful intervention and an expensive procedure.As our population ages, the expense of these interventions is expected to grow and hence its impact on healthcare costs will also grow. To ensure that TJA is available to all those who would benefit, it is incumbent that healthcare providers control the cost of these procedures. As orthopaedic surgeons, we must be at the forefront of this effort. The purpose of this review is to outline strategies to control or even decrease TJA cost without negatively affecting outcomes.This concept is at the center of value-based medicine and must guide our decision-making processes.

  11. Examination of synovial fluid hyaluronan quantity and quality in stifle joints of dogs with osteoarthritis.

    PubMed

    Venable, Rachel O; Stoker, Aaron M; Cook, Cristi R; Cockrell, Mary K; Cook, James L

    2008-12-01

    To determine the quantity (concentration) and quality (molecular weight) of synovial fluid hyaluronan with respect to presence and severity of osteoarthritis in stifle joints of dogs. 21 purpose-bred dogs and 6 clinically affected large-breed dogs (cranial cruciate ligament [CrCL] disease with secondary osteoarthritis). Research dogs underwent arthroscopic surgery in 1 stifle joint to induce osteoarthritis via CrCL transection (CrCLt; n=5 stifle joints), femoral condylar articular cartilage groove creation (GR; 6), or meniscal release (MR; 5); 5 had sham surgery (SH) performed. Contralateral stifle joints (n=21) were used as unoperated control joints. Synovial fluid was obtained from research dogs at time 0 and 12 weeks after surgery and from clinically affected dogs prior to surgery. All dogs were assessed for lameness, radiographic signs of osteoarthritis, and pathologic findings on arthroscopy as well as for quantity and quality of hyaluronan. Clinically affected dogs had significantly greater degrees of pathologic findings, compared with dogs with surgically induced osteoarthritis (ie, those with CrCLt, GR, and MR stifle joints), and with respect to lameness scores, radiographic signs of osteoarthritis, pathologic findings on arthroscopy, and synovial fluid hyaluronan concentration. Synovial fluid from stifle joints of dogs with surgically induced osteoarthritis had hyaluronan bands at 35 kd on western blots that synovial fluid from SH and clinically affected stifle joints did not. Synovial fluid hyaluronan quantity and quality were altered in stifle joints of dogs with osteoarthritis, compared with control stifle joints. A specific hyaluronan protein fragment may be associated with early pathologic changes in affected joints.

  12. Undergraduate Research Experience for STEM Students: Efforts and Outcomes

    ERIC Educational Resources Information Center

    Zhang, Chuanlei; Swaid, Samar

    2017-01-01

    Undergraduate research for STEM students involves students who are attending college or universities pursuing a bachelor's degree, majoring in fields related to Science, Technology, Engineering and Mathematics (STEM). Research experience for STEM undergraduates has been viewed as a positive experience that has several benefits such as developing…

  13. Refining patterns of joint hypermobility, habitus, and orthopedic traits in joint hypermobility syndrome and Ehlers-Danlos syndrome, hypermobility type.

    PubMed

    Morlino, Silvia; Dordoni, Chiara; Sperduti, Isabella; Venturini, Marina; Celletti, Claudia; Camerota, Filippo; Colombi, Marina; Castori, Marco

    2017-04-01

    Joint hypermobility syndrome (JHS) and Ehlers-Danlos syndrome, hypermobility type (EDS-HT) are two overlapping heritable disorders (JHS/EDS-HT) recognized by separated sets of diagnostic criteria and still lack a confirmatory test. This descriptive research was aimed at better characterizing the clinical phenotype of JHS/EDS-HT with focus on available diagnostic criteria, and in order to propose novel features and assessment strategies. One hundred and eighty-nine (163 females, 26 males; age: 2-73 years) patients from two Italian reference centers were investigated for Beighton score, range of motion in 21 additional joints, rate and sites of dislocations and sprains, recurrent soft-tissue injuries, tendon and muscle ruptures, body mass index, arm span/height ratio, wrist and thumb signs, and 12 additional orthopedic features. Rough rates were compared by age, sex, and handedness with a series of parametric and non-parametric tools. Multiple correspondence analysis was carried out for possible co-segregations of features. Beighton score and hypermobility at other joints were influenced by age at diagnosis. Rate and sites of joint instability complications did not vary according to age at diagnosis except for soft-tissue injuries. No major difference was registered by sex and dominant versus non-dominant body side. At multiple correspondence analysis, selected features tend to co-segregate in a dichotomous distribution. Dolichostenomelia and arachnodactyly segregated independently. This study pointed out a more protean musculoskeletal phenotype than previously considered according to available diagnostic criteria for JHS/EDS-HT. Our findings corroborated the need for a re-thinking of JHS/EDS-HT on clinical grounds in order to find better therapeutic and research strategies. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

  14. Novel joint cupping clinical maneuver for ultrasonographic detection of knee joint effusions.

    PubMed

    Uryasev, Oleg; Joseph, Oliver C; McNamara, John P; Dallas, Apostolos P

    2013-11-01

    Knee effusions occur due to traumatic and atraumatic causes. Clinical diagnosis currently relies on several provocative techniques to demonstrate knee joint effusions. Portable bedside ultrasonography (US) is becoming an adjunct to diagnosis of effusions. We hypothesized that a US approach with a clinical joint cupping maneuver increases sensitivity in identifying effusions as compared to US alone. Using unembalmed cadaver knees, we injected fluid to create effusions up to 10 mL. Each effusion volume was measured in a lateral transverse location with respect to the patella. For each effusion we applied a joint cupping maneuver from an inferior approach, and re-measured the effusion. With increased volume of saline infusion, the mean depth of effusion on ultrasound imaging increased as well. Using a 2-mm cutoff, we visualized an effusion without the joint cupping maneuver at 2.5 mL and with the joint cupping technique at 1 mL. Mean effusion diameter increased on average 0.26 cm for the joint cupping maneuver as compared to without the maneuver. The effusion depth was statistically different at 2.5 and 7.5 mL (P < .05). Utilizing a joint cupping technique in combination with US is a valuable tool in assessing knee effusions, especially those of subclinical levels. Effusion measurements are complicated by uneven distribution of effusion fluid. A clinical joint cupping maneuver concentrates the fluid in one recess of the joint, increasing the likelihood of fluid detection using US. © 2013 Elsevier Inc. All rights reserved.

  15. Development of remountable joints and heat removable techniques for high-temperature superconducting magnets

    NASA Astrophysics Data System (ADS)

    Hashizume, H.; Ito, S.; Yanagi, N.; Tamura, H.; Sagara, A.

    2018-02-01

    Segment fabrication is now a candidate for the design of superconducting helical magnets in the helical fusion reactor FFHR-d1, which adopts the joint winding of high-temperature superconducting (HTS) helical coils as a primary option and the ‘remountable’ HTS helical coil as an advanced option. This paper reports on recent progress in two key technologies: the mechanical joints (remountable joints) of the HTS conductors and the metal porous media inserted into the cooling channel for segment fabrication. Through our research activities it has been revealed that heat treatment during fabrication of the joint can reduce joint resistance and its dispersion, which can shorten the fabrication process and be applied to bent conductor joints. Also, heat transfer correlations of the cooling channel were established to evaluate heat transfer performance with various cryogenic coolants based on the correlations to analyze the thermal stability of the joint.

  16. Shear fracture of jointed steel plates of bolted joints under impact load

    NASA Astrophysics Data System (ADS)

    Daimaruya, M.; Fujiki, H.; Ambarita, H.; Kobayashi, H.; Shin, H.-S.

    2013-07-01

    The present study is concerned with the development of a fracture criterion for the impact fracture of jointed steel plates of bolted joints used in a car body, which contributes to crash simulations by CAE. We focus our attention on the shear fracture of the jointed steel plates of lap-bolted joints in the suspension of a car under impact load. Members of lap-bolted joints are modelled as a pair of steel plates connected by a bolt. One of the plates is a specimen subjected to plastic deformation and fracture and the other is a jig subjected to elastic deformation only. Three kinds of steel plate specimens are examined, i.e., a common steel plate with a tensile strength of 270 MPa and high tensile strength steel plates of 440 and 590 MPa used for cars. The impact shear test was performed using the split Hopkinson bar technique for tension impact, together with the static test using a universal testing machine INSTRON 5586. The behaviour of the shear stress and deformation up to rupture taking place in the joint was discussed. The obtained results suggest that a stress-based fracture criterion may be developed for the impact fracture of jointed steel plates of a lap-bolted joint.

  17. Computational Modelling and Movement Analysis of Hip Joint with Muscles

    NASA Astrophysics Data System (ADS)

    Siswanto, W. A.; Yoon, C. C.; Salleh, S. Md.; Ngali, M. Z.; Yusup, Eliza M.

    2017-01-01

    In this study, the model of hip joint and the main muscles are modelled by finite elements. The parts included in the model are hip joint, hemi pelvis, gluteus maximus, quadratus femoris and gamellus inferior. The materials that used in these model are isotropic elastic, Mooney Rivlin and Neo-hookean. The hip resultant force of the normal gait and stair climbing are applied on the model of hip joint. The responses of displacement, stress and strain of the muscles are then recorded. FEBio non-linear solver for biomechanics is employed to conduct the simulation of the model of hip joint with muscles. The contact interfaces that used in this model are sliding contact and tied contact. From the analysis results, the gluteus maximus has the maximum displacement, stress and strain in the stair climbing. Quadratus femoris and gamellus inferior has the maximum displacement and strain in the normal gait however the maximum stress in the stair climbing. Besides that, the computational model of hip joint with muscles is produced for research and investigation platform. The model can be used as a visualization platform of hip joint.

  18. Tensile Properties of Under-Matched Weld Joints for 950 MPa Steel.

    NASA Astrophysics Data System (ADS)

    Yamamoto, Kouji; Arakawa, Toshiaki; Akazawa, Nobuki; Yamamoto, Kousei; Matsuo, Hiroki; Nakagara, Kiyoyuki; Suita, Yoshikazu

    In welding of 950 MPa-class high tensile strength steel, preheating is crucial in order to avoid cold cracks, which, however, eventually increases welding deformations. One way to decrease welding deformations is lowering preheating temperature by using under-matched weld metal. Toyota and others clarify that although breaking elongation can decrease due to plastic constraint effect under certain conditions, static tensile of under-matched weld joints is comparable to that of base metal. However, there has still been no report about joint static tensile of under-matched weld joints applied to 950 MPa-class high tensile strength steel. In this study, we aim to research tensile strength and fatigue strength of under-matched weld joints applied to 950 MPa-class high tensile steel.

  19. The Relationship among Rank, Experience, and Accounting Faculty Effort Allocations.

    ERIC Educational Resources Information Center

    Cox, Clifford T.

    1991-01-01

    Analysis of questionnaires returned by 16 of 450 accounting faculty found that (1) experience is inversely related to the amount of effort allocated to research alone and to the aggregate of teaching, research, and service; and (2) a significant positive relationship was found between rank and administrative activity. (SK)

  20. A parametric shell analysis of the shuttle 51-L SRB AFT field joint

    NASA Technical Reports Server (NTRS)

    Davis, Randall C.; Bowman, Lynn M.; Hughes, Robert M., IV; Jackson, Brian J.

    1990-01-01

    Following the Shuttle 51-L accident, an investigation was conducted to determine the cause of the failure. Investigators at the Langley Research Center focused attention on the structural behavior of the field joints with O-ring seals in the steel solid rocket booster (SRB) cases. The shell-of-revolution computer program BOSOR4 was used to model the aft field joint of the solid rocket booster case. The shell model consisted of the SRB wall and joint geometry present during the Shuttle 51-L flight. A parametric study of the joint was performed on the geometry, including joint clearances, contact between the joint components, and on the loads, induced and applied. In addition combinations of geometry and loads were evaluated. The analytical results from the parametric study showed that contact between the joint components was a primary contributor to allowing hot gases to blow by the O-rings. Based upon understanding the original joint behavior, various proposed joint modifications are shown and analyzed in order to provide additional insight and information. Finally, experimental results from a hydro-static pressurization of a test rocket booster case to study joint motion are presented and verified analytically.

  1. Creep properties of Pb-free solder joints

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Song, H.G.; Morris Jr., J.W.; Hua, F.

    2002-04-01

    Describes the creep behavior of three Sn-rich solders that have become candidates for use in Pb-free solder joints: Sn-3.5Ag, Sn-3Ag-0.5Cu and Sn-0.7Cu. The three solders show the same general behavior when tested in thin joints between Cu and Ni/Au metallized pads at temperatures between 60 and 130 C. Their steady-state creep rates are separated into two regimes with different stress exponents(n). The low-stress exponents range from {approx}3-6, while the high-stress exponents are anomalously high (7-12). Strikingly, the high-stress exponent has a strong temperature dependence near room temperature, increasing significantly as the temperature drops from 95 to 60 C. The anomalousmore » creep behavior of the solders appears to be due to the dominant Sn constituent. Joints of pure Sn have stress exponents, n, that change with stress and temperature almost exactly like those of the Sn-rich solder joints. Research on creep in bulk samples of pure Sn suggests that the anomalous temperature dependence of the stress exponent may show a change in the dominant mechanism of creep. Whatever its source, it has the consequence that conventional constitutive relations for steady-state creep must be used with caution in treating Sn-rich solder joints, and qualification tests that are intended to verify performance should be carefully designed.« less

  2. Cognitive dissonance in children: justification of effort or contrast?

    PubMed

    Alessandri, Jérôme; Darcheville, Jean-Claude; Zentall, Thomas R

    2008-06-01

    Justification of effort is a form of cognitive dissonance in which the subjective value of an outcome is directly related to the effort that went into obtaining it. However, it is likely that in social contexts (such as the requirements for joining a group) an inference can be made (perhaps incorrectly) that an outcome that requires greater effort to obtain in fact has greater value. Here we present evidence that a cognitive dissonance effect can be found in children under conditions that offer better control for the social value of the outcome. This effect is quite similar to contrast effects that recently have been studied in animals. We suggest that contrast between the effort required to obtain the outcome and the outcome itself provides a more parsimonious account of this phenomenon and perhaps other related cognitive dissonance phenomena as well. Research will be needed to identify cognitive dissonance processes that are different from contrast effects of this kind.

  3. Boise Hydrogeophysical Research Site: Control Volume/Test Cell and Community Research Asset

    NASA Astrophysics Data System (ADS)

    Barrash, W.; Bradford, J.; Malama, B.

    2008-12-01

    The Boise Hydrogeophysical Research Site (BHRS) is a research wellfield or field-scale test facility developed in a shallow, coarse, fluvial aquifer with the objectives of supporting: (a) development of cost- effective, non- or minimally-invasive quantitative characterization and imaging methods in heterogeneous aquifers using hydrologic and geophysical techniques; (b) examination of fundamental relationships and processes at multiple scales; (c) testing theories and models for groundwater flow and solute transport; and (d) educating and training of students in multidisciplinary subsurface science and engineering. The design of the wells and the wellfield support modular use and reoccupation of wells for a wide range of single-well, cross-hole, multiwell and multilevel hydrologic, geophysical, and combined hydrologic-geophysical experiments. Efforts to date by Boise State researchers and collaborators have been largely focused on: (a) establishing the 3D distributions of geologic, hydrologic, and geophysical parameters which can then be used as the basis for jointly inverting hard and soft data to return the 3D K distribution and (b) developing subsurface measurement and imaging methods including tomographic characterization and imaging methods. At this point the hydrostratigraphic framework of the BHRS is known to be a hierarchical multi-scale system which includes layers and lenses that are recognized with geologic, hydrologic, radar, seismic, and EM methods; details are now emerging which may allow 3D deterministic characterization of zones and/or material variations at the meter scale in the central wellfield. Also the site design and subsurface framework have supported a variety of testing configurations for joint hydrologic and geophysical experiments. Going forward we recognize the opportunity to increase the R&D returns from use of the BHRS with additional infrastructure (especially for monitoring the vadose zone and surface water-groundwater interactions

  4. Work and fatigue characteristics of unsuited and suited humans during isolated isokinetic joint motions

    NASA Technical Reports Server (NTRS)

    Gonzalez, L. Javier; Maida, J. C.; Miles, E. H.; Rajulu, S. L.; Pandya, A. K.

    2002-01-01

    The effects of a pressurized suit on human performance were investigated. The suit is known as an Extra-Vehicular Mobility Unit (EMU) and is worn by astronauts while working outside their spacecraft in a low earth orbit. Isolated isokinetic joint torques of three female and three male subjects (all experienced users of the suit in 1G gravity) were measured while working at 100% and 80% of their maximum voluntary torque (MVT, which is synonymous with maximum voluntary contraction (MVC)). It was found that the average decrease in the total amount of work (the sum of the work in each repetition until fatigue) done when the subjects were wearing the EMU were 48% and 41% while working at 100% and 80% MVT, respectively. There is a clear relationship between the MVT and the time and amount of work done until fatigue. Here, the time to fatigue is defined as the ending time of the repetition for which the computed work done during that repetition dropped below 50% of the work done during the first repetition. In general the stronger joints took longer to fatigue and did more work than the weaker joints. It was found that the EMU decreases the work output at the wrist and shoulder joints the most, due to the EMU joint geometry. The EMU also decreased the joint range of motion. The average total amount of work done by the test subjects increased by 5.2% (20.4%) for the unsuited (suited) case, when the test subjects decreased the level of effort from 100% to 80% MVT. Also, the average time to fatigue increased by 9.2% (25.6%) for the unsuited (suited) case, when the test subjects decreased the level of effort from 100% to 80% MVT. It was also found that the experimentally measured torque decay could be predicted by a logarithmic equation. The absolute average errors in the predictions were found to be 18.3% and 18.9% for the unsuited and suited subjects, respectively, when working at 100% MVT, and 22.5% and 18.8% for the unsuited and suited subjects, respectively, when working

  5. Behavioral Assessment of Listening Effort Using a Dual-Task Paradigm.

    PubMed

    Gagné, Jean-Pierre; Besser, Jana; Lemke, Ulrike

    2017-01-01

    Published investigations ( n = 29) in which a dual-task experimental paradigm was employed to measure listening effort during speech understanding in younger and older adults were reviewed. A summary of the main findings reported in the articles is provided with respect to the participants' age-group and hearing status. Effects of different signal characteristics, such as the test modality, on dual-task outcomes are evaluated, and associations with cognitive abilities and self-report measures of listening effort are described. Then, several procedural issues associated with the use of dual-task experiment paradigms are discussed. Finally, some issues that warrant future research are addressed. The review revealed large variability in the dual-task experimental paradigms that have been used to measure the listening effort expended during speech understanding. The differences in experimental procedures used across studies make it difficult to draw firm conclusions concerning the optimal choice of dual-task paradigm or the sensitivity of specific paradigms to different types of experimental manipulations. In general, the analysis confirmed that dual-task paradigms have been used successfully to measure differences in effort under different experimental conditions, in both younger and older adults. Several research questions that warrant further investigation in order to better understand and characterize the intricacies of dual-task paradigms were identified.

  6. Behavioral Assessment of Listening Effort Using a Dual-Task Paradigm

    PubMed Central

    Besser, Jana; Lemke, Ulrike

    2017-01-01

    Published investigations (n = 29) in which a dual-task experimental paradigm was employed to measure listening effort during speech understanding in younger and older adults were reviewed. A summary of the main findings reported in the articles is provided with respect to the participants’ age-group and hearing status. Effects of different signal characteristics, such as the test modality, on dual-task outcomes are evaluated, and associations with cognitive abilities and self-report measures of listening effort are described. Then, several procedural issues associated with the use of dual-task experiment paradigms are discussed. Finally, some issues that warrant future research are addressed. The review revealed large variability in the dual-task experimental paradigms that have been used to measure the listening effort expended during speech understanding. The differences in experimental procedures used across studies make it difficult to draw firm conclusions concerning the optimal choice of dual-task paradigm or the sensitivity of specific paradigms to different types of experimental manipulations. In general, the analysis confirmed that dual-task paradigms have been used successfully to measure differences in effort under different experimental conditions, in both younger and older adults. Several research questions that warrant further investigation in order to better understand and characterize the intricacies of dual-task paradigms were identified. PMID:28091178

  7. Space Tracking and Surveillance System (STSS) Cryogenic Technology Efforts and Needs

    NASA Astrophysics Data System (ADS)

    Kolb, I. L.; Curran, D. G. T.; Lee, C. S.

    2004-06-01

    The Missile Defense Agency's (MDA) STSS program, the former Space Based Infrared Systems (SBIRS) Low, has been actively supporting and working to advance space-borne cryocooler technology through efforts with the Air Force Research Lab (AFRL) and Small Business Innovation Research (SBIR) program. The envisioned infrared satellite system requires high efficiency, low power, and low weight cooling in a range of temperature and cooling loads below 120K for reliable 10-year operation to meet mission needs. This paper describes cryocooler efforts previously and currently supported by STSS and the possible future cryogenic requirements for later technology insertion.

  8. A Novel Multiscale Design of Interfaces for Polymeric Composites and Bonded Joints using Additive Manufacturing

    DTIC Science & Technology

    2016-09-13

    AFRL-AFOSR-VA-TR-2016-0317 A Novel Multiscale Design of Interfaces for Polymeric Composites and Bonded Joints using Additive Manufacturing Pavana...Composites and Bonded Joints using Additive Manufacturing AWARD NO.: FA9550-15-1-0216 AGENCY NAME: The Air Force Office of Scientific Research (AFOSR), Ar...20 3 Additive Manufacturing for Bonded Composite Joints 21 3.1 Introduction

  9. Multivariate Analysis of High Through-Put Adhesively Bonded Single Lap Joints: Experimental and Workflow Protocols

    DTIC Science & Technology

    2016-06-01

    unlimited. v List of Tables Table 1 Single-lap-joint experimental parameters ..............................................7 Table 2 Survey ...Joints: Experimental and Workflow Protocols by Robert E Jensen, Daniel C DeSchepper, and David P Flanagan Approved for...TR-7696 ● JUNE 2016 US Army Research Laboratory Multivariate Analysis of High Through-Put Adhesively Bonded Single Lap Joints: Experimental

  10. Early, asymptomatic stage of degenerative joint disease in canine hip joints.

    PubMed

    Lust, G; Summers, B A

    1981-11-01

    The early stages of degenerative joint disease were investigated in coxofemoral joints from dogs with a hereditary predisposition to hip dysplasia. Alterations observed included mild nonsuppurative synovitis, increased volume of both synovial fluid and the ligamentum teres, and focal degenerative articular cartilage lesions. On radiologic examination, subluxation of the femoral head was seen, but only in the most severely affected joints. Synovial inflammation with increased synovial fluid and ligament volumes were indicators of early degenerative joint disease in dogs. These changes seemed to coincide with, or perhaps to precede, microscopic evidence for articular cartilage degeneration and occurred before radiologic abnormalities were detected.

  11. Joint Center for Artificial Photosynthesis

    ScienceCinema

    Koval, Carl; Lee, Kenny; Houle, Frances; Lewis, Na

    2018-05-30

    The Joint Center for Artificial Photosynthesis (JCAP) is the nation's largest research program dedicated to the development of an artificial solar-fuel generation technology. Established in 2010 as a U.S. Department of Energy (DOE) Energy Innovation Hub, JCAP aims to find a cost-effective method to produce fuels using only sunlight, water, and carbon dioxide as inputs. JCAP brings together more than 140 top scientists and researchers from the California Institute of Technology and its lead partner, Berkeley Lab, along with collaborators from the SLAC National Accelerator Laboratory, and the University of California campuses at Irvine and San Diego.

  12. Joint Center for Artificial Photosynthesis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Koval, Carl; Lee, Kenny; Houle, Frances

    2013-12-10

    The Joint Center for Artificial Photosynthesis (JCAP) is the nation's largest research program dedicated to the development of an artificial solar-fuel generation technology. Established in 2010 as a U.S. Department of Energy (DOE) Energy Innovation Hub, JCAP aims to find a cost-effective method to produce fuels using only sunlight, water, and carbon dioxide as inputs. JCAP brings together more than 140 top scientists and researchers from the California Institute of Technology and its lead partner, Berkeley Lab, along with collaborators from the SLAC National Accelerator Laboratory, and the University of California campuses at Irvine and San Diego.

  13. Joint Contact Stress

    PubMed Central

    Brand, Richard A

    2005-01-01

    A joint's normal mechanical history contributes to the maintenance of articular cartilage and underlying bone. Loading facilitates the flow of nutrients into cartilage and waste products away, and additionally provides the mechanical signals essential for normal cell and tissue maintenance. Deleteriously low or high contact stresses have been presumed to result in joint deterioration, and particular aspects of the mechanical environment may facilitate repair of damaged cartilage. For decades, investigators have explored static joint contact stresses (under some more or less arbitrary condition) as a surrogate of the relevant mechanical history. Contact stresses have been estimated in vitro in many joints and in a number of species, although only rarely in vivo. Despite a number of widely varying techniques (and spatial resolutions) to measure these contact stresses, reported ranges of static peak normal stresses are relatively similar from joint to joint across species, and in the range of 0.5 to 5.0 MPa. This suggests vertebrate diarthrodial joints have evolved to achieve similar mechanical design criteria. Available evidence also suggests some disorders of cartilage deterioration are associated with somewhat higher peak pressures ranging from 1-20 MPa, but overlapping the range of normal pressures. Some evidence and considerable logic suggests static contact stresses per se do not predict cartilage responses, but rather temporal aspects of the contact stress history. Static contact stresses may therefore not be a reasonable surrogate for biomechanical studies. Rather, temporal and spatial aspects of the loading history undoubtedly induce beneficial and deleterious biological responses. Finally, since all articular cartilage experiences similar stresses, the concept of a "weight-bearing" versus a "non-weight-bearing" joint seems flawed, and should be abandoned. PMID:16089079

  14. Mapping Fishing Effort through AIS Data

    PubMed Central

    Natale, Fabrizio; Gibin, Maurizio; Alessandrini, Alfredo; Vespe, Michele; Paulrud, Anton

    2015-01-01

    Several research initiatives have been undertaken to map fishing effort at high spatial resolution using the Vessel Monitoring System (VMS). An alternative to the VMS is represented by the Automatic Identification System (AIS), which in the EU became compulsory in May 2014 for all fishing vessels of length above 15 meters. The aim of this paper is to assess the uptake of the AIS in the EU fishing fleet and the feasibility of producing a map of fishing effort with high spatial and temporal resolution at European scale. After analysing a large AIS dataset for the period January-August 2014 and covering most of the EU waters, we show that AIS was adopted by around 75% of EU fishing vessels above 15 meters of length. Using the Swedish fleet as a case study, we developed a method to identify fishing activity based on the analysis of individual vessels’ speed profiles and produce a high resolution map of fishing effort based on AIS data. The method was validated using detailed logbook data and proved to be sufficiently accurate and computationally efficient to identify fishing grounds and effort in the case of trawlers, which represent the largest portion of the EU fishing fleet above 15 meters of length. Issues still to be addressed before extending the exercise to the entire EU fleet are the assessment of coverage levels of the AIS data for all EU waters and the identification of fishing activity in the case of vessels other than trawlers. PMID:26098430

  15. Mapping Fishing Effort through AIS Data.

    PubMed

    Natale, Fabrizio; Gibin, Maurizio; Alessandrini, Alfredo; Vespe, Michele; Paulrud, Anton

    2015-01-01

    Several research initiatives have been undertaken to map fishing effort at high spatial resolution using the Vessel Monitoring System (VMS). An alternative to the VMS is represented by the Automatic Identification System (AIS), which in the EU became compulsory in May 2014 for all fishing vessels of length above 15 meters. The aim of this paper is to assess the uptake of the AIS in the EU fishing fleet and the feasibility of producing a map of fishing effort with high spatial and temporal resolution at European scale. After analysing a large AIS dataset for the period January-August 2014 and covering most of the EU waters, we show that AIS was adopted by around 75% of EU fishing vessels above 15 meters of length. Using the Swedish fleet as a case study, we developed a method to identify fishing activity based on the analysis of individual vessels' speed profiles and produce a high resolution map of fishing effort based on AIS data. The method was validated using detailed logbook data and proved to be sufficiently accurate and computationally efficient to identify fishing grounds and effort in the case of trawlers, which represent the largest portion of the EU fishing fleet above 15 meters of length. Issues still to be addressed before extending the exercise to the entire EU fleet are the assessment of coverage levels of the AIS data for all EU waters and the identification of fishing activity in the case of vessels other than trawlers.

  16. US and Cuban Scientists Forge Collaboration on Arbovirus Research.

    PubMed

    Pérez-Ávila, Jorge; Guzmán-Tirado, Maria G; Fraga-Nodarse, Jorge; Handley, Gray; Meegan, James; Pelegrino-Martínez de la Cotera, Jose L; Fauci, Anthony S

    2018-04-01

    After December 17, 2014, when the US and Cuban governments announced their intent to restore relations, the two countries participated in various exchange activities in an effort to encourage cooperation in public health, health research and biomedical sciences. The conference entitled Exploring Opportunities for Arbovirus Research Collaboration, hosted at Havana's Hotel Nacional, was part of these efforts and was the first major US-Cuban scientific conference in over 50 years. Its purpose was to share information about current arbovirus research and recent findings, and to explore opportunities for future joint research. The nearly 100 participants included leading arbovirus and vector transmission experts from ten US academic institutions, NIH, CDC, FDA and the US Department of Defense. Cuban participants included researchers, clinicians and students from Cuba's Ministry of Public Health, Pedro Kourí Tropical Medicine Institute, Center for Genetic Engineering and Biotechnology, Center for State Control of Medicines and Medical Devices and other health research and regulatory organizations. Topics highlighted at the three-day meeting included surveillance, research and epidemiology; pathogenesis, immunology and virology; treatment and diagnosis; vector biology and control; vaccine development and clinical trials; and regulatory matters. Concurrent breakout discussions focused on novel vector control, nonvector transmission, community engagement, Zika in pregnancy, and workforce development. Following the conference, the Pedro Kourí Tropical Medicine Institute and the US National Institute of Allergic and Infectious Diseases have continued to explore ways to encourage and support scientists in Cuba and the USA who wish to pursue arbovirus research cooperation to advance scientific discovery to improve disease prevention and control. KEYWORDS Arboviruses, flavivirus, Zika virus, chikungunya virus, dengue virus, research, disease vectors, Cuba, USA.

  17. The ENCCA-WP7/EuroSarc/EEC/PROVABES/EURAMOS 3rd European Bone Sarcoma Networking Meeting/Joint Workshop of EU Bone Sarcoma Translational Research Networks; Vienna, Austria, September 24-25, 2015. Workshop Report.

    PubMed

    Kager, Leo; Whelan, Jeremy; Dirksen, Uta; Hassan, Bass; Anninga, Jakob; Bennister, Lindsey; Bovée, Judith V M G; Brennan, Bernadette; Broto, Javier M; Brugières, Laurence; Cleton-Jansen, Anne-Marie; Copland, Christopher; Dutour, Aurélie; Fagioli, Franca; Ferrari, Stefano; Fiocco, Marta; Fleuren, Emmy; Gaspar, Nathalie; Gelderblom, Hans; Gerrand, Craig; Gerß, Joachim; Gonzato, Ornella; van der Graaf, Winette; Hecker-Nolting, Stefanie; Herrero-Martín, David; Klco-Brosius, Stephanie; Kovar, Heinrich; Ladenstein, Ruth; Lancia, Carlo; LeDeley, Marie-Cecile; McCabe, Martin G; Metzler, Markus; Myklebost, Ola; Nathrath, Michaela; Picci, Piero; Potratz, Jenny; Redini, Françoise; Richter, Günther H S; Reinke, Denise; Rutkowski, Piotr; Scotlandi, Katia; Strauss, Sandra; Thomas, David; Tirado, Oscar M; Tirode, Franck; Vassal, Gilles; Bielack, Stefan S

    2016-01-01

    This report summarizes the results of the 3rd Joint ENCCA-WP7, EuroSarc, EEC, PROVABES, and EURAMOS European Bone Sarcoma Network Meeting, which was held at the Children's Cancer Research Institute in Vienna, Austria on September 24-25, 2015. The joint bone sarcoma network meetings bring together European bone sarcoma researchers to present and discuss current knowledge on bone sarcoma biology, genetics, immunology, as well as results from preclinical investigations and clinical trials, to generate novel hypotheses for collaborative biological and clinical investigations. The ultimate goal is to further improve therapy and outcome in patients with bone sarcomas.

  18. Electron gun with a transmission photocathode for the Joint Institute for Nuclear Research photoinjector

    NASA Astrophysics Data System (ADS)

    Balalykin, N. I.; Minashkin, V. F.; Nozdrin, M. A.; Shirkov, G. D.; Zelenogorskii, V. V.; Gacheva, E. I.; Potemkin, A. K.; Huran, J.

    2017-10-01

    Photocathode electron guns are key to the generation of high-quality electron bunches, which are currently the primary source of electrons for linear electron accelerators. The photogun test bench built at the Joint Institute for Nuclear Research (JINR) is currently being used to further develop the hollow (backside irradiated) photocathode concept. A major achievement was the replacement of the hollow photocathode by a technologically more feasible transmission photocathode made from a metal mesh that serves as a substrate for films of various photomaterials. A number of thin-film cathodes on quartz glass substrates are fabricated by photolithography. The vectorial photoeffect (related to the surface-normal component of the wave electric field) is observed and found to significantly affect the quantum efficiency. The dependence of the quantum efficiency of diamond-like carbon photocathodes on the manufacturing technology is investigated. The Rutherford backscattering and elastic recoil detection techniques are combined to carry out an elemental analysis of the films. An estimate of the emittance of a 400 pC electron beam is obtained using the cross-section method.

  19. Effortful echolalia.

    PubMed

    Hadano, K; Nakamura, H; Hamanaka, T

    1998-02-01

    We report three cases of effortful echolalia in patients with cerebral infarction. The clinical picture of speech disturbance is associated with Type 1 Transcortical Motor Aphasia (TCMA, Goldstein, 1915). The patients always spoke nonfluently with loss of speech initiative, dysarthria, dysprosody, agrammatism, and increased effort and were unable to repeat sentences longer than those containing four or six words. In conversation, they first repeated a few words spoken to them, and then produced self initiated speech. The initial repetition as well as the subsequent self initiated speech, which were realized equally laboriously, can be regarded as mitigated echolalia (Pick, 1924). They were always aware of their own echolalia and tried to control it without effect. These cases demonstrate that neither the ability to repeat nor fluent speech are always necessary for echolalia. The possibility that a lesion in the left medial frontal lobe, including the supplementary motor area, plays an important role in effortful echolalia is discussed.

  20. Cost Minimization for Joint Energy Management and Production Scheduling Using Particle Swarm Optimization

    NASA Astrophysics Data System (ADS)

    Shah, Rahul H.

    Production costs account for the largest share of the overall cost of manufacturing facilities. With the U.S. industrial sector becoming more and more competitive, manufacturers are looking for more cost and resource efficient working practices. Operations management and production planning have shown their capability to dramatically reduce manufacturing costs and increase system robustness. When implementing operations related decision making and planning, two fields that have shown to be most effective are maintenance and energy. Unfortunately, the current research that integrates both is limited. Additionally, these studies fail to consider parameter domains and optimization on joint energy and maintenance driven production planning. Accordingly, production planning methodology that considers maintenance and energy is investigated. Two models are presented to achieve well-rounded operating strategy. The first is a joint energy and maintenance production scheduling model. The second is a cost per part model considering maintenance, energy, and production. The proposed methodology will involve a Time-of-Use electricity demand response program, buffer and holding capacity, station reliability, production rate, station rated power, and more. In practice, the scheduling problem can be used to determine a joint energy, maintenance, and production schedule. Meanwhile, the cost per part model can be used to: (1) test the sensitivity of the obtained optimal production schedule and its corresponding savings by varying key production system parameters; and (2) to determine optimal system parameter combinations when using the joint energy, maintenance, and production planning model. Additionally, a factor analysis on the system parameters is conducted and the corresponding performance of the production schedule under variable parameter conditions, is evaluated. Also, parameter optimization guidelines that incorporate maintenance and energy parameter decision making in the