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Sample records for jugular um caso

  1. The jugular venous pressure revisited

    PubMed Central

    CHIACO, JOHN MICHAEL S. CHUA; PARIKH, NISHA I.; FERGUSSON, DAVID J.

    2016-01-01

    Assessment of the jugular venous pressure is often inadequately performed and undervalued. Here, we review the physiologic and anatomic basis for the jugular venous pressure, including the discrepancy between right atrial and central venous pressures. We also describe the correct method of evaluating this clinical finding and review the clinical relevance of the jugular venous pressure, especially its value in assessing the severity and response to treatment of congestive heart failure. Waveforms reflective of specific conditions are also discussed. PMID:24085809

  2. Intradural jugular foramen tumors.

    PubMed

    Mattos, João Paulo; Ramina, Ricardo; Borges, Wilson; Ghizoni, Enrico; Fernandes, Yvens B; Paschoal, Jorge R; Honorato, Donizeti C; Borges, Guilherme

    2004-12-01

    Eleven patients with jugular foramen lesions with or without extradural extension were operated at University Hospital of Campinas (UNICAMP), in Campinas, Brazil, between 1998 and 2001. Neck dissection, mastoidectomy without transposition of the facial nerve and myofascial flap reconstruction of the cranial base with an especially developed technique were carried out in 7 patients. Four patients were operated using retrosigmoid craniectomy. Total excision was accomplished in 9 cases. All patients did not show evidence of disease progression at least after 2 years follow-up. There was no mortality. New lower cranial nerve deficits occurred in 5 patients. Nine maintain or improved their preoperative status based on Karnofsky and Glasgow Outcome Scale. A complex anatomy of this region demand wide exposures for treat those tumors. For this reason, an adequate approach for curative resection of most lesions and an efficient skull base reconstruction decreasing postoperative morbidity are essential.

  3. Surgery of Glomus Jugulare Tumors.

    PubMed

    Pareschi, Roberto; Righini, Stefano; Destito, Domenico; Raucci, Aldo Falco; Colombo, Stefano

    2003-08-01

    The treatment of choice for glomus jugulare tumors is still controversial. High rates of morbidity, incomplete resection, and the aggressive behavior of these tumors are the main arguments for advocates of primary radiotherapy. However, constant refinements in skull base techniques have made complete resection of these lesions a realistic goal. The high probability of achieving local control of these tumors by surgery has convinced us to support this option strongly. Between 1993 and 2000 we diagnosed 52 glomus tumors of the temporal bone. Of these patients, only 42 had a class C lesion (glomus jugulare) and were included in this study; 37 of these patients underwent surgery, 10 of whom had intracranial extension of the disease. The overall resection rate was 96 %. Facial nerve function at 1 year was House-Brackmann grade I to II in 52 % of patients and grade III or better in 84 % of patients. Hospitalization was shorter than 14 days in 33 patients (89 %). All patients with pharyngolaryngeal palsy had sufficient compensation at discharge. Twelve vocal chord Teflon injections were performed after surgery to reduce hoarseness and aspiration. No patient died. No relapse was observed (mean follow-up, 4.9 years).

  4. Jugular foramen: anatomic and computed tomographic study

    SciTech Connect

    Daniels, D.L.; Williams, A.L.; Haughton, V.M.

    1984-01-01

    The computed tomographic (CT) appearance of the jugular foramen was examined in detail, and anatomic and CT sections were correlated. The pars nervosa and pars vascularis were identified, and, with intravenous contrast enhancement, a rapid sequence of scans at a gantry angle of +30/sup 0/ to the canthomeatal line demonstrated cranial nerves IX, X, and XI. The osseous margins of the jugular foramen were best shown by CT at planes of sections parallel and positive (0/sup 0/-30/sup 0/) to the canthomeatal line. CT can be used to evaluate osseous anatomy and the jugular foramen with precision sufficient to confidently exclude an intracanalicular mass.

  5. The jugular bulb diverticulum. A radioanatomic investigation.

    PubMed

    Wadin, K; Wilbrand, H

    1986-01-01

    Two hundred and forty-five temporal bone specimens were examined radiographically. Subsequently the topographic relationship between the jugular fossa and surrounding structures was evaluated in plastic casts of the specimens. Fifty-eight casts showed a high jugular fossa and in 17 a jugular bulb diverticulum was found. A diverticulum is regarded as an anomaly of the high jugular bulb and presumably has a potential for expansion. Most frequently a diverticulum was directed medially into the space between the internal acoustic meatus, the vestibular aqueduct and the posterior cranial fossa. Seven diverticula reached the level of the internal acoustic meatus. Encroachment upon the vestibular aqueduct was seen in 4 casts and both the internal acoustic meatus and the cochlear aqueduct were very close to the diverticulum. A few diverticula were directed postero-laterally close to the facial canal and the stapedius muscle. The investigation was supplemented with a selected clinical material of radiographs of temporal bones with high fossae. The results corresponded to those of the experimental investigation. The jugular bulb diverticulum is a relatively common feature and should be regarded as an anomaly with a potential to give rise to clinical symptoms consequent to its intrusion upon surrounding structures.

  6. Subclavian artery- internal jugular vein fistula and heart failure: complication of internal jugular vein catheterization.

    PubMed

    Prakash, Jai; Takhellambam, Brojen; Ghosh, Biplab; Choudhury, Tauhidul Alam; Singh, Shivendra; Sharma, Om Prakash

    2013-02-01

    Hemodialysis in patients with end-stage renal disease (ESRD) requires vascular access which can be either temporary or permanent. However, these procedures are not without complications. Arterial puncture is the most common immediate complication and pseudoaneurysm formation is the most common late sequel of internal jugular venous catheterization (IJVC). However, arterio-venous fistula (AVF) formatiorn following IJVC is rare. We are reporting a case of AVF formation between subclavian artery (SCA) and internal jugular vein (IJV) following IJVC which later on leads to the development of cardiac failure.

  7. Primary leiomyosarcoma of the jugular vein in a dog

    PubMed Central

    Pierini, Alessio; Cinti, Filippo; Binanti, Diana; Pisani, Guido

    2017-01-01

    A four-year-old, male, Labrador retriever was referred for removal of a spindle cell sarcoma involving the right jugular vein. A post-contrast CT scan showed a seven-centimeter subcutaneous mass originated from the right external jugular vein, which was partially obstructed and showing contrast stasis, suggested a primary intravascular tumor of the jugular vein. The mass was resected, and histological evaluation was consistent with grade II intravenous spindle cell sarcoma of the jugular vein. Immunohistochemical positivity for vimentin, desmin, and αSMA antibody and negativity for S-100 protein confirmed venous leiomyosarcoma. The dog received five doses of intravenous doxorubicin, and there was no recurrence of the tumor 30 months post treatment. In dogs, primary intravascular sarcomas are rare and primary venous leiomyosarcoma has not been described. A venous tumor may be considered as a differential diagnosis in dogs with ventral neck swelling. PMID:28331835

  8. Radiosurgery of Glomus Jugulare Tumors: A Meta-Analysis

    SciTech Connect

    Guss, Zachary D.; Batra, Sachin; Limb, Charles J.; Li, Gordon; Sughrue, Michael E.; Redmond, Kristin; Rigamonti, Daniele; Parsa, Andrew T.; Chang, Steven; Kleinberg, Lawrence; Lim, Michael

    2011-11-15

    Purpose: During the past two decades, radiosurgery has arisen as a promising approach to the management of glomus jugulare. In the present study, we report on a systematic review and meta-analysis of the available published data on the radiosurgical management of glomus jugulare tumors. Methods and Materials: To identify eligible studies, systematic searches of all glomus jugulare tumors treated with radiosurgery were conducted in major scientific publication databases. The data search yielded 19 studies, which were included in the meta-analysis. The data from 335 glomus jugulare patients were extracted. The fixed effects pooled proportions were calculated from the data when Cochrane's statistic was statistically insignificant and the inconsistency among studies was <25%. Bias was assessed using the Egger funnel plot test. Results: Across all studies, 97% of patients achieved tumor control, and 95% of patients achieved clinical control. Eight studies reported a mean or median follow-up time of >36 months. In these studies, 95% of patients achieved clinical control and 96% achieved tumor control. The gamma knife, linear accelerator, and CyberKnife technologies all exhibited high rates of tumor and clinical control. Conclusions: The present study reports the results of a meta-analysis for the radiosurgical management of glomus jugulare. Because of its high effectiveness, we suggest considering radiosurgery for the primary management of glomus jugulare tumors.

  9. Jugular venous reflux on magnetic resonance angiography and radionuclide venography

    PubMed Central

    Okada, Tomohisa; Okuchi, Sachi; Yamamoto, Akira; Kanagaki, Mitsunori; Fujimoto, Koji; Togashi, Kaori

    2016-01-01

    Background The relationship between the signal from retrograde venous flow on magnetic resonance angiography (MRA) and retrograde upward flow from the left brachiocephalic vein has not been explored. Purpose To reveal the frequency of jugular venous reflux using MRA and nuclear venography in patients being evaluated for cerebral volume and blood flow. Material and Methods A total of 229 patients with cognitive disturbance who had undergone brain magnetic resonance imaging (MRI) and single-photon emission computed tomography (SPECT) on the same day to evaluate cerebral blood flow were evaluated. Jugular venous reflux was measured on MRA and nuclear venography, which was conducted just after injection of N-isopropyl-123I-p-iodoamphetamine for the SPECT study. Results MRA showed jugular reflux in seven patients on the right side, and in 22 on the left. Nuclear venography showed jugular reflux in six patients on the right side, and in 20 on the left. Conclusion Jugular venous reflux was observed mostly on the left side. Retrograde flow was observed on both MRA and nuclear venography in half of the cases, with the rest only on one of the modalities. PMID:27994882

  10. Veno-venous bypass in experimental liver transplantation: portal-jugular versus caval-portal-jugular.

    PubMed

    Falcini, F; Martini, E; Marsili, M; Benassai, C; Fabbri, L P; Tanini, R; Linden, M; Simoncini, R; Filipponi, F; Cataliotti, L

    1990-04-01

    This study was undertaken to compare the changes in physiologic variables caused by the use of two different types of pump-assisted veno-venous bypass during experimental liver transplantation. The experiments, performed on female pigs weighing 30 +/- 2 kg, were divided into two groups depending on the bypass used. During the anhepatic phase a pump-assisted portal-jugular (PJ) bypass was used in Group 1 (n = 8) at a flow rate of 15 ml kg-1-min-1, while a pump-assisted caval-portal-jugular (CPJ) bypass was used in Group 2 (n = 8) at a flow rate of 20 ml kg-1-min-1. Intraoperative haemodynamics, pulmonary gas exchange, haematological and serum biochemical parameters were evaluated. Postoperative animal survival rate and complications associated with the bypass used were evaluated. Mean pulmonary artery pressure (Ppa) and pulmonary vascular resistance (Pvr) showed significantly different behaviour in the two groups, whereas the remaining parameters all showed the same trend. Thus an earlier and more substantial increase in Ppa and Pvr values was found in Group 1 when compared to Group 2 during the anhepatic phase. The different behaviour shown by Group 1 may depend on the release of circulating vasoactive substances generated following pelvic venous congestion caused by the temporary clamping of the inferior vena cava. In conclusion, this study indicates that the pump-assisted CPJ bypass is more suitable than the pump-assisted PJ bypass. Furthermore, in order to obtain better results it should be used routinely in porcine liver transplantation.

  11. Papilloedema and Increased Intracranial Pressure as a Result of Unilateral Jugular Vein Thrombosis

    PubMed Central

    Thandra, Abhishek; Jun, Bokkwan; Chuquilin, Miguel

    2015-01-01

    Abstract Intracranial hypertension and papilloedema are known to develop secondary to cerebral sinus or bilateral jugular vein thrombosis. However, in rare cases, unilateral jugular vein thrombosis may lead to increased intracranial pressure and papilloedema with resultant headache and vision changes. We describe a 45-year-old patient with squamous cell carcinoma of the larynx that developed right jugular vein thrombosis after chemoradiation therapy with cetuximab. This was later complicated by intracranial hypertension and papilloedema. The normal cerebral venous drainage, the potential role of chemoradiation therapy on the aetiology of jugular vein thrombosis, and the mechanism of increased intracranial pressure secondary to unilateral jugular vein occlusion are discussed. PMID:27928352

  12. Comparison of internal jugular vein dilation between Valsalva maneuver and proximal internal jugular vein compression

    PubMed Central

    Seong, Hyeonjoo; Kang, Bora; Kim, Giwoon

    2016-01-01

    Objective The Valsalva maneuver is recognized as an effective method to dilate the internal jugular vein (IJV). However, this maneuver cannot be performed in many cases, such as children and unconscious patients. The aim of this study was to evaluate the effectiveness of proximal IJV compression, which can easily be performed, regardless of patient cooperation. Methods Healthy adult volunteers were recruited from tertiary hospital employees. Basic anatomic and physiologic data were collected. The subjects lay down as if they were undergoing IJV catheter insertion, in the supine position with their necks turned 30 degrees to the left. The main outcome was the cross-sectional area (CSA) of the distal IJV as measured by ultrasound in four stages. The first stage was sham without any maneuver. The second was Valsalva maneuver, the third was digital IJV compression, and the fourth was digital compression accompanied by simultaneous Valsalva maneuver. Results A total of 41 volunteers were enrolled. Twenty-six (63.41%) were male with an average age of 28.15±2.85 years. Mean height was 170.74±8.66 cm and mean neck circumference was 35.28±3.87 cm. The mean CSA-IJV was 1.06±0.36 cm2 without any maneuver. It increased to 1.34±0.45 cm2 with Valsalva maneuver (P<0.001), to 1.26±0.41 cm2 with digital compression (P<0.001), and to 1.41±0.47 cm2 with the two maneuvers combined (P=0.01). Conclusion Digital proximal IJV compression effectively dilates the distal IJV. When performed simultaneously with the Valsalva maneuver, the effect was enhanced. PMID:28168225

  13. [Thrombosis of the internal jugular vein secondary to acute pharyngotonsillitis].

    PubMed

    Cuestas, Giselle; Lijdens, Yesica; Demarchi, María Victoria; Martínez Corvalán, María Pía; Razetti, Juan; Boccio, Carlos

    2014-12-01

    Acute pharyngotonsillitis is one of the most common diseases in children and adolescents. The most frequent etiology is virus, followed by bacteria. The main bacterial agent is beta hemolytic Streptococcus group A. A rare complication of pharyngeal infectious processes is septic thrombophlebitis of the internal jugular vein. The diagnosis is suspected in the presence of an inflammatory unilateral neck swelling. The diagnosis is confirmed by contrast computed tomography. Treatment consists of prolonged administration of antibiotics, being the use of anticoagulants controversial. Early diagnosis and appropriate treatment are essential to prevent persistent vascular occlusion and progression of the thrombus, which can cause pulmonary emboli. In the present study, we present a teenager with thrombophlebitis of the internal jugular vein secondary to acute streptococcal pharyngotonsillitis. Clinical manifestations, diagnostic methods and treatment of this rare vascular complication are described herein.

  14. The origin of mean arterial and jugular venous blood pressures in giraffes.

    PubMed

    Mitchell, Graham; Maloney, Shane K; Mitchell, Duncan; Keegan, D James

    2006-07-01

    Using a mechanical model of the giraffe neck and head circulation consisting of a rigid, ascending, 'carotid' limb, a 'cranial' circulation that could be rigid or collapsible, and a descending, 'jugular' limb that also could be rigid or collapsible, we have analyzed the origin of the high arterial and venous pressures in giraffe, and whether blood flow is assisted by a siphon. When the tubes were rigid and the 'jugular' limb exit was lower than the 'carotid' limb entrance a siphon operated, 'carotid' hydrostatic pressures became more negative, and flow was 3.3 l min(-1) but ceased when the 'cranial' and 'jugular' limbs were collapsible or when the 'jugular' limb was opened to the atmosphere. Pumping water through the model produced positive pressures in the 'carotid' limb similar to those found in giraffe. Applying an external 'tissue' pressure to the 'jugular' tube during pump flow produced the typical pressures found in the jugular vein in giraffe. Constriction of the lowest, 'jugular cuff', portion of the 'jugular' limb showed that the cuff may augment the orthostatic reflex during head raising. Except when all tubes were rigid, pressures were unaffected by a siphon. We conclude that mean arterial blood pressure in giraffes is a consequence of the hydrostatic pressure generated by the column of blood in the neck, that tissue pressure around the collapsible jugular vein produces the known jugular pressures, and that a siphon does not assist flow through the cranial circulation.

  15. Congenital internal jugular vein aneurysm in an infant: A rare entity.

    PubMed

    Awasthy, Neeraj; Khandelwal, Nidhi; Iyer, Krishna S

    2016-05-01

    A 1-month old baby boy presented with a mass at the root of the neck. On investigation, a saccular aneurysm arising from the internal jugular vein was diagnosed. The aneurysm was excised after ligating the patent internal jugular vein above and below the origin of the aneurysm. Histopathology confirmed the diagnosis of a vascular malformation. Vascular malformation of the internal jugular vein, presenting as neck mass, is extremely rare with no case described in neonates. We present one such interesting case.

  16. External Jugular Vein Thrombosis as a Sign of Metastatic Breast Cancer

    PubMed Central

    Yalaza, Metin; Kafadar, Mehmet Tolga; Çıvgın, Esra Yurduseven; Düzgün, Arife Polat

    2017-01-01

    External jugular vein thrombosis is a rare vascular event which may lead fatal complication such as sepsis and pulmonary embolism. Its relation to the visceral solid tumor as an etiologic factor has been established well. Although external jugular vein thrombosis may be seen in malignancy, it is unusual to see as a sign of breast cancer. Most of the external jugular vein thrombosis occurs secondary to compression of the vein. Vascular thrombosis due to hypercoagulability is known as Trousseau syndrome. Herein, we present a case of metastatic breast cancer which presented with external jugular vein thrombosis; Trousseau syndrome. PMID:28331768

  17. Rapid methods for jugular bleeding of dogs requiring one technician.

    PubMed

    Frisk, C S; Richardson, M R

    1979-06-01

    Two methods were used to collect blood from the jugular vein of dogs. In both techniques, only one technician was required. A rope with a slip knot was placed around the base of the neck to assist in restraint and act as a tourniquet for the vein. The technician used one hand to restrain the dog by the muzzle and position the head. The other hand was used for collecting the sample. One of the methods could be accomplished with the dog in its cage. The bleeding techniques were rapid, requiring approximately 1 minute per dog.

  18. The Jugular Foramen Schwannomas: Review of the Large Surgical Series

    PubMed Central

    2008-01-01

    Objective Jugular foramen schwannomas are uncommon pathological conditions. This article is constituted for screening these tumors in a wide perspective. Materials One-hundred-and-ninty-nine patients published in 19 articles between 1984 to 2007 years was collected from Medline/Index Medicus. Results The series consist of 83 male and 98 female. The mean age of 199 operated patients was 40.4 years. The lesion located on the right side in 32 patients and on the left side in 60 patients. The most common presenting clinical symptoms were hearing loss, tinnitus, disphagia, ataxia, and hoarseness. Complete tumor removal was achieved in 159 patients. In fourteen patients tumor reappeared unexpectedly. The tumor was thought to originate from the glossopharyngeal nerve in forty seven cases; vagal nerve in twenty six cases; and cranial accessory nerve in eleven cases. The most common postoperative complications were lower cranial nerve palsy and facial nerve palsy. Cerebrospinal fluid leakage, meningitis, aspiration pneumonia and mastoiditis were seen as other complications. Conclusion This review shows that jugular foramen schwannomas still have prominently high morbidity and those complications caused by postoperative lower cranial nerve injury are life threat. PMID:19119464

  19. An unusual condition during internal jugular vein catheterisation: vertebral artery catheterisation.

    PubMed

    Korkmaz, Ozge; Göksel, Sabahattin; Söylemez, Burçak; Durmuş, Kasim; Işbir, Ahmet Cemil; Berkan, Öcal

    Vertebral artery cannulation is an unusual complication during internal jugular vein cannulation. We report a case of vertebral artery cannulation, which occurred during an attempt to cannulate the right internal jugular vein, and we discuss the management of such a rare complication.

  20. Catheter-related bacteremia from femoral and central internal jugular venous access.

    PubMed

    Lorente, L; Jiménez, A; García, C; Galván, R; Castedo, J; Martín, M M; Mora, M L

    2008-09-01

    The objective of this prospective observational study was to determine the influence of femoral and central internal jugular venous catheters on the incidence of catheter-related bacteremia (CRB). We included patients admitted to a 12-bed polyvalent medico-surgical intensive care unit over 4 years who received one or more femoral or central internal jugular venous catheters. We diagnosed 16 cases of CRB in 208 femoral catheters and 22 in 515 central internal jugular venous catheters. We found a higher incidence of CRB with femoral (9.52 per 1,000 catheter days) than with central internal jugular venous access (4.83 per 1,000 catheter days; risk ratio = 1.93; 95% confidence interval: 1.03-3.73; P = 0.04). Central internal jugular venous access could be considered a safer route of venous access than femoral access in minimizing the risk of central venous catheter-related bacteremia.

  1. An ectopic hamartomatous thymoma compressing left jugular vein.

    PubMed

    Huang, L; Zhao, L; Chai, Y

    2014-01-01

    Ectopic hamartomatous thymoma (EHT) is an extremely rare benign neoplasm. It is usually found at the root of the neck (frequently on the left) and does not usually impact adjacent tissues in clinically significant ways. While EHT manifests distinct pathological features, the lesion is either asymptomatic or may show nonspecific clinical features. We report one case of EHT which was assumed to be of low malignant potential since it severely compressed the inlet of left internal jugular vein as seen by computed tomography scan. To the best of our knowledge, this clinical finding of EHT is very rare. After the diagnosis and treatment of this patient, we believe that EHT or suspected EHT should be treated less invasively.

  2. Jugular thrombophlebitis in horses: A review of fibrinolysis, thrombus formation, and clinical management

    PubMed Central

    Dias, Deborah Penteado Martins; de Lacerda Neto, José Corrêa

    2013-01-01

    Thrombophlebitis of the jugular vein is commonly observed in horses, particularly during intensive care, and leads to local and systemic inflammatory responses as well as head and neck circulatory impairment. Thrombolytic therapy is widely used in human practice with the aim of thrombus dissolution and recanalization of the injured vessels. There are similarities between human and horse coagulation and fibrinolytic processes. This review examines the fibrinolytic system, thrombus formation, and the clinical management of jugular thrombophlebitis, including thrombolytic therapy. There is evidence that early regional thrombolytic therapy for jugular thrombophlebitis in horses may be effective to achieve sustained recanalization. PMID:23814304

  3. Misplaced central venous catheter in the jugular venous arch exposed during dissection before sternotomy.

    PubMed

    Jung, Tae-Eun; Jee, Daelim

    2008-11-01

    Subclavian vein catheterization rarely results in misplacement of the central venous catheter (CVC) into the jugular venous arch (JVA). We present a case of misplacement of the CVC into the JVA during cardiac surgery.

  4. A survey of the use of ultrasound guidance in internal jugular venous cannulation.

    PubMed

    McGrattan, T; Duffty, J; Green, J S; O'Donnell, N

    2008-11-01

    It has been that suggested the use of two dimensional (2D) ultrasound to facilitate placement of central venous cannulae in the internal jugular vein improves patient safety and reduces complications. Since the introduction of the National Institute for Clinical Excellence Technology Appraisal Guideline Number 49 in 2002, promoting the use of ultrasound in placement of internal jugular venous cannulae, utilisation of ultrasound has increased throughout the United Kingdom. We report the findings of a postal survey of 2000 senior anaesthetists in the United Kingdom which enquired about their use of ultrasound for internal jugular vein cannulae placement. Only 27% use 2D ultrasound as their first choice technique, although 35% use it as their first choice when teaching. There was no significant difference in practice between those working within a sub specialty in anaesthesia. There continues to be discrepancies between the application of the guideline and how senior anaesthetists both site and teach the placement of internal jugular vein central venous cannulae.

  5. Rare primary leiomyosarcoma of the internal jugular vein with cervical extravascular extension.

    PubMed

    Moreno-Sánchez, M; González-García, R; Moreno-García, C; Toro, W; Monje, F

    2017-02-01

    Leiomysarcoma of intravascular origin is a rare malignant tumour of the soft tissue. We present what is, to our knowledge, the first example of one that has arisen from the wall of the internal jugular vein.

  6. Internal jugular vein cannulation: A comparison of three techniques

    PubMed Central

    Ray, Bikash R; Mohan, Virender K; Kashyap, Lokesh; Shende, Dilip; Darlong, Vanlal M; Pandey, Ravindra K

    2013-01-01

    Context: Ultrasound-guided internal jugular vein (IJV) cannulation is known for increasing success rate and decreasing rate of complications. The ultrasound image can be used as a real time image during cannulation or to prelocate the IJV before attempting cannulation. Aims: This study compares both the ultrasound-guided technique with the classical anatomical landmark technique (central approach) for right IJV cannulation in terms of success rate, complications, and time for cannulation. Settings and Design: A prospective, randomized, observational study was conducted at a tertiary care hospital. Material and Methods: One hundred twenty patients requiring IJV cannulation were included in this study and were randomly allocated in three groups. Number of attempts, success rate, venous access time, catheterization time, and complications were observed in each group. Statistical Analysis Used: Statistical analysis was performed using STATA-9 software. Demographic data were compared using one-way analysis of variance (ANOVA). Nonparametric data were compared using the Kruskall–Wallis test, and multiple comparisons were done applying The Mann–Whitney test for individual pairs of groups. Nominal data were compared by applying the Chi-square test and Fisher exact test. Results: Successful cannulation (≤3 attempt) was achieved in 90.83% of patients without any statistical significant difference between the groups. Venous access time and catheterization time was found to be significantly less in both the ultrasound groups than the anatomical land mark group. Number of attempts and success in first attempt was similar between the groups. Conclusions: Both the ultrasound techniques are found to be better than the anatomical landmark technique. Further, ultrasound-guided prelocation was found to be as effective as ultrasound guided real-time imaging technique for right IJV cannulation. PMID:24106363

  7. Jugular venous pooling during lowering of the head affects blood pressure of the anesthetized giraffe.

    PubMed

    Brøndum, E; Hasenkam, J M; Secher, N H; Bertelsen, M F; Grøndahl, C; Petersen, K K; Buhl, R; Aalkjaer, C; Baandrup, U; Nygaard, H; Smerup, M; Stegmann, F; Sloth, E; Ostergaard, K H; Nissen, P; Runge, M; Pitsillides, K; Wang, T

    2009-10-01

    How blood flow and pressure to the giraffe's brain are regulated when drinking remains debated. We measured simultaneous blood flow, pressure, and cross-sectional area in the carotid artery and jugular vein of five anesthetized and spontaneously breathing giraffes. The giraffes were suspended in the upright position so that we could lower the head. In the upright position, mean arterial pressure (MAP) was 193 +/- 11 mmHg (mean +/- SE), carotid flow was 0.7 +/- 0.2 l/min, and carotid cross-sectional area was 0.85 +/- 0.04 cm(2). Central venous pressure (CVP) was 4 +/- 2 mmHg, jugular flow was 0.7 +/- 0.2 l/min, and jugular cross-sectional area was 0.14 +/- 0.04 cm(2) (n = 4). Carotid arterial and jugular venous pressures at head level were 118 +/- 9 and -7 +/- 4 mmHg, respectively. When the head was lowered, MAP decreased to 131 +/- 13 mmHg, while carotid cross-sectional area and flow remained unchanged. Cardiac output was reduced by 30%, CVP decreased to -1 +/- 2 mmHg (P < 0.01), and jugular flow ceased as the jugular cross-sectional area increased to 3.2 +/- 0.6 cm(2) (P < 0.01), corresponding to accumulation of approximately 1.2 l of blood in the veins. When the head was raised, the jugular veins collapsed and blood was returned to the central circulation, and CVP and cardiac output were restored. The results demonstrate that in the upright-positioned, anesthetized giraffe cerebral blood flow is governed by arterial pressure without support of a siphon mechanism and that when the head is lowered, blood accumulates in the vein, affecting MAP.

  8. Successful endovascular therapy of a penetrating zone III jugular bulb injury. A case report.

    PubMed

    Yamanaka, K; Yamamoto, A; Ishida, K; Matsuzaki, J; Ozaki, T; Ishihara, M; Shimahara, Y; Nakajima, S; Sadamitsu, D; Yamasaki, M

    2012-06-01

    Penetrating venous injuries via Zone III of the neck extended over jugular bulb are rare. The optimal strategies for these venous injuries are currently unknown because many of the vital structures in this region are poorly accessible to the surgeon and therefore it is difficult to control bleeding. A 76-year-old man got drunk and fell down onto a paper door. The wooden framework of the paper door was broken and got stuck deep in the right side of his neck. Enhanced computed tomography showed the wood stick had penetrated through the right jugular foramen and injured the jugular bulb. We successfully performed right sigmoid and jugular vein occlusion via an endovascular approach using Guglielmi detachable coils at first and then to draw out the wood stick in order to avoid venous bleeding. To our best knowledge, these venous injuries have reported in only four cases. Only one case was performed by endovascular approach using n-butyl cyanoacrylate (NBCA). Coil embolization is much better than NBCA in the light of reducing complications due to adhesion to the inserted wood stick and embolization of unintended vessels. Venous occlusion using coil embolization is the best way to treat a penetrating jugular bulb injury via zone III because of reducing the hemorrhage and air embolism.

  9. Noninvasive measurement of internal jugular venous oxygen saturation by photoacoustic imaging

    NASA Astrophysics Data System (ADS)

    Garcia-Uribe, Alejandro; Erpelding, Todd N.; Ke, Haixin; Reddy, Kavya; Sharma, Anshuman; Wang, Lihong V.

    2014-03-01

    The metabolic rate and oxygen consumption of the brain is reflected in jugular venous oxygen saturation. In many clinical conditions, such as head trauma, stroke, and low cardiac output states, the brain is at risk for hypoxic-ischemic injury. The current gold standard for monitoring brain oxygenation is invasive and requires jugular vein catheterization under fluoroscopic guidance; and therefore it is rarely used. Photo-acoustic tomography in combination with ultrasound can be used to estimate oxygen saturation of the internal jugular vein in real-time. This noninvasive method will enable earlier detection and prevention of impending hypoxic brain injury. A wavelength-tunable dye laser pumped by a Nd:YAG laser delivers light through an optical fiber bundle, and a modified commercial ultrasound imaging system (Philips iU22) detects both the pulse-echo ultrasound (US) and photoacoustic (PA) signals. A custom-built multichannel data acquisition system renders co-registered ultrasound and photoacoustic images at 5 frames per second. After the jugular vein was localized in healthy volunteers, dualwavelength PA images were used to calculate the blood hemoglobin oxygen saturation from the internal jugular vein in vivo. The preliminary results raise confidence that this emerging technology can be used clinically as an accurate, noninvasive indicator of cerebral oxygenation.

  10. [Pharyngeal hemorrhaging due to iatrogenic false aneurysm. Complication after cannulation of the internal jugular vein].

    PubMed

    Kreckel, V; Langwara, H

    2009-03-01

    Catheterization of the internal jugular vein is used for temporary access to the central vein in patients with acute or chronic renal failure. The most frequent problem is the arterial puncture and accidental placement of the large catheter in an artery. This case report describes a rare secondary complication by accidental catheterization of the right common carotid artery after intended dual lumen catheter insertion into the right internal jugular vein. A false aneurysm with pharyngeal hemorrhaging developed 2 weeks after the puncture. The diagnosis was made using colour-Doppler ultrasound and the aneurysm was treated with vascular surgery.

  11. [Internal jugular thrombophlebitis: complications of the cervical oncological surgery. A case report].

    PubMed

    Alvarez Marcos, C A; Noval Menéndez, J; Alfonso Megido, J; Domínguez Iglesias, F; Hevia Llama, R; Ramos Barriga, M A

    1995-01-01

    Internal jugular vein thrombophlebitis is an infrequent complications, associated in the past to pharyngeal and amygdaline infections but related today to the use of catheters and intravenous drugs. The present paper reports the case of a patient who underwent total laryngectomy and functional neck dissection, developing recurrent neumonias and sepsis in the postoperative period which were secondary to an homolateral jugular thrombophlebitis. A physical exploration with no findings and the poor resolution of CT scan and ultrasound due to postsurgical alterations, lead to a late diagnosis and fatal evolution, in spite of the medical and surgical treatment.

  12. Crouzon’s Syndrome with Life-Threatening Ear Bleed: Ruptured Jugular Vein Diverticulum Treated by Endovascular Embolization

    SciTech Connect

    Mondel, Prabath Kumar Anand, Sunanda Limaye, Uday S.

    2015-08-15

    Crouzon’s syndrome is the commonest variety of syndromic craniosynostosis. Life-threatening ear bleed due to ruptured jugular venous diverticulum in Crouzon’s syndrome has not been described previously. In patients with syndromic craniosynostosis, definitive repair of jugular diverticulum by open surgery is fraught with high risk of bleeding, poor functional outcomes, and even death. A 24-year-old woman with Crouzon’s syndrome presented with conductive hearing loss and recurrent episodes of torrential bleeding from her left ear. On computed tomography, a defect in the roof of jugular fossa containing jugular venous diverticulum immediately inferior to the bony external auditory canal was seen. The clinical presentation, imaging features, and endovascular management of Crouzon’s syndrome due to a ruptured jugular venous diverticulum is described.

  13. Accidental subclavian artery catheterization during attempted internal jugular central venous catheter placement: a case report.

    PubMed

    Paliwal, Bharat; Kamal, Manoj; Purohit, Anamika; Rana, Kirti; Chouhan, Dilip Singh

    2015-01-01

    Central venous catheter placement has been routinely employed for anesthetic and intensive care management. Despite proper technique used and expertise complications do occur; some of which are related to catheter misplacements. We report a case in which subclavian artery was accidently catheterized during attempted internal jugular venous cannulation.

  14. Brachial plexus compression due to subclavian artery pseudoaneurysm from internal jugular vein catheterization

    PubMed Central

    Mol, T. N.; Gupta, A.; Narain, U.

    2017-01-01

    Internal jugular vein (IJV) catheterization has become the preferred approach for temporary vascular access for hemodialysis. However, complications such as internal carotid artery puncture, vessel erosion, thrombosis, and infection may occur. We report a case of brachial plexus palsy due to compression by right subclavian artery pseudoaneurysm as a result of IJV catheterization in a patient who was under maintenance hemodialysis. PMID:28356671

  15. Internal Jugular Vein Cannulation: An Ultrasound-Guided Technique Versus a Landmark-Guided Technique

    PubMed Central

    Turker, Gurkan; Kaya, Fatma Nur; Gurbet, Alp; Aksu, Hale; Erdogan, Cuneyt; Atlas, Ahmet

    2009-01-01

    OBJECTIVES To compare the landmark-guided technique versus the ultrasound-guided technique for internal jugular vein cannulation in spontaneously breathing patients. METHODS A total of 380 patients who required internal jugular vein cannulation were randomly assigned to receive internal jugular vein cannulation using either the landmark- or ultrasound-guided technique in Bursa, Uludag University Faculty of Medicine, between April and November, 2008. Failed catheter placement, risk of complications from placement, risk of failure on first attempt at placement, number of attempts until successful catheterization, time to successful catheterization and the demographics of each patient were recorded. RESULTS The overall complication rate was higher in the landmark group than in the ultrasound-guided group (p < 0.01). Carotid puncture rate and hematoma were more frequent in the landmark group than in the ultrasound-guided group (p < 0.05). The number of attempts for successful placement was significantly higher in the landmark group than in the ultrasound-guided group, which was accompanied by a significantly increased access time observed in the landmark group (p < 0.05 and p < 0.01, respectively). Although there were a higher number of attempts, longer access time, and a more frequent complication rate in the landmark group, the success rate was found to be comparable between the two groups. CONCLUSION The findings of this study indicate that internal jugular vein catheterization guided by real-time ultrasound results in a lower access time and a lower rate of immediate complications. PMID:19841706

  16. Collet-Sicard syndrome: a rare but important presentation of internal jugular vein thrombosis.

    PubMed

    Neo, Shermyn; Lee, Kim En

    2017-01-01

    We describe a rare neurological presentation of internal jugular vein thrombosis induced by central venous catheter placement in a patient with cancer. A 71-year-old man gave a 3-week history of dysphagia and dysarthria with left-sided neck pain and headache. He was receiving chemotherapy for appendiceal adenocarcinoma. On examination, he had left 9th-12th cranial neuropathies, manifesting as voice hoarseness, decreased palatal movement, absent gag reflex, weakness of scapular elevation and left-sided tongue wasting. CT scan of neck showed the left subclavian central venous catheter tip was in the left internal jugular vein. Skull base MRI showed thrombus within the left jugular foramen extending intracranially. We diagnosed Collet-Sicard syndrome secondary to thrombosis in the sigmoid-jugular venous complex. His headache and neck pain resolved 2 days after removing the catheter and starting anticoagulation. Collet-Sicard syndrome is an unusual syndrome of lower cranial nerve palsies, often signifying disease at the skull base, including malignancy, trauma or vascular causes.

  17. Calcium micro-depositions in jugular truncular venous malformations revealed by Synchrotron-based XRF imaging.

    PubMed

    Pascolo, Lorella; Gianoncelli, Alessandra; Rizzardi, Clara; Tisato, Veronica; Salomé, Murielle; Calligaro, Carla; Salvi, Fabrizio; Paterson, David; Zamboni, Paolo

    2014-10-07

    It has been recently demonstrated that the internal jugular vein may exhibit abnormalities classified as truncular venous malformations (TVMs). The investigation of possible morphological and biochemical anomalies at jugular tissue level could help to better understand the link between brain venous drainage and neurodegenerative disorders, recently found associated with jugular TVMs. To this end we performed sequential X-ray Fluorescence (XRF) analyses on jugular tissue samples from two TVM patients and two control subjects, using complementary energies at three different synchrotrons. This investigation, coupled with conventional histological analyses, revealed anomalous micro-formations in the pathological tissues and allowed the determination of their elemental composition. Rapid XRF analyses on large tissue areas at 12.74 keV showed an increased Ca presence in the pathological samples, mainly localized in tunica adventitia microvessels. Investigations at lower energy demonstrated that the high Ca level corresponded to micro-calcifications, also containing P and Mg. We suggest that advanced synchrotron XRF micro-spectroscopy is an important analytical tool in revealing biochemical changes, which cannot be accessed by conventional investigations. Further research on a larger number of samples is needed to understand the pathogenic significance of Ca micro-depositions detected on the intramural vessels of vein walls affected by TVMs.

  18. The Prevalence of High-Riding Jugular Bulb in Patients with Suspected Endolymphatic Hydrops

    PubMed Central

    Brook, Christopher D.; Buch, Karen; Kaufmann, Matthew; Sakai, Osamu; Devaiah, Anand K.

    2015-01-01

    Background To determine the prevalence of a high-riding jugular bulb (HRJB) in the endolymphatic hydrops population. Methods This was a retrospective chart and radiology review of patients seen at a tertiary care medical center. Patients were identified using the International Classification of Diseases, 9th edition, code 386.xx (Meniere disease–unspecified), and were required to have undergone an imaging study that included views of the jugular bulb that were available for review. A radiologist then evaluated all of the imaging studies for evidence of HRJB or inner ear dehiscence with a jugular bulb abnormality. Results The prevalence of a HRJB in all endolymphatic hydrops patients was 9.0% (7 of 78), and it was 4.5% (7 of 156) in all ears. The prevalence of HRJB ipsilateral to an ear with endolymphatic hydrops was 4.6% (4 of 88 ears); it was 4.4% (3 of 68 ears) in ears without endolymphatic hydrops. The incidence of inner ear dehiscence with a HRJB was 1.3% (1 of 78). Electrocochleography results were not correlated with jugular bulb volume. Discussion The results of this study indicate that a small subset of patients treated for endolymphatic hydrops patients have a HRJB. Overall, these results suggest that HRJB does not play a major role in endolymphatic hydrops, although it may play a role in a few isolated patients. PMID:26682126

  19. The Prevalence of High-Riding Jugular Bulb in Patients with Suspected Endolymphatic Hydrops.

    PubMed

    Brook, Christopher D; Buch, Karen; Kaufmann, Matthew; Sakai, Osamu; Devaiah, Anand K

    2015-12-01

    Background To determine the prevalence of a high-riding jugular bulb (HRJB) in the endolymphatic hydrops population. Methods This was a retrospective chart and radiology review of patients seen at a tertiary care medical center. Patients were identified using the International Classification of Diseases, 9th edition, code 386.xx (Meniere disease-unspecified), and were required to have undergone an imaging study that included views of the jugular bulb that were available for review. A radiologist then evaluated all of the imaging studies for evidence of HRJB or inner ear dehiscence with a jugular bulb abnormality. Results The prevalence of a HRJB in all endolymphatic hydrops patients was 9.0% (7 of 78), and it was 4.5% (7 of 156) in all ears. The prevalence of HRJB ipsilateral to an ear with endolymphatic hydrops was 4.6% (4 of 88 ears); it was 4.4% (3 of 68 ears) in ears without endolymphatic hydrops. The incidence of inner ear dehiscence with a HRJB was 1.3% (1 of 78). Electrocochleography results were not correlated with jugular bulb volume. Discussion The results of this study indicate that a small subset of patients treated for endolymphatic hydrops patients have a HRJB. Overall, these results suggest that HRJB does not play a major role in endolymphatic hydrops, although it may play a role in a few isolated patients.

  20. Common femoral vein reconstruction using internal jugular vein after blast injury.

    PubMed

    Holt, Andrew M; West, Charles A; Davis, James A; Gilani, Ramyar; Askenasy, Eric

    2014-10-01

    Common femoral vein traumatic injuries are rare. Surgical management is controversial and by nature case specific. In this report, we present an unusual case of an isolated common femoral vein injury from a gunshot blast repaired with an interposition internal jugular vein bypass. To our knowledge, this is the first reported case of an isolated common femoral vein reconstructed in this manner.

  1. Usefulness of Groshong catheters for central venous access via the external jugular vein.

    PubMed

    Ishizuka, Mitsuru; Nagata, Hitoshi; Takagi, Kazutoshi; Horie, Toru; Sawada, Tokihiko; Kubota, Keiichi

    2008-01-01

    This study was designed to evaluate the usefulness of central venous access via the external jugular vein (EJV) employing Groshong catheters, and to compare the complications with those of conventional internal jugular venous catheterization. Central venous access was achieved by insertion of a single-lumen 4.0 Fr Groshong catheter via the EJV or internal jugular vein (IJV) with a single puncture. Complications associated with insertion and central venous catheter-related bloodstream infection (CVC-RBSI) were evaluated from the database. Two hundred and twenty-five patients received 400 catheters for a total period of 5377 catheter-days. Ninety-six patients underwent 201 internal jugular venous catheter (IJV-C) procedures for 2381 catheter-days, and 129 patients underwent 199 external jugular venous catheter (EJV-C) procedures for 2996 catheter-days. Use of EJV-C was associated with a longer catheter insertion length (p < .01) and period (p < .01), a larger number of operations (p < .01), and more frequent use of total parenteral nutrition (TPN) (p < .01) and less frequent use of chemotherapy (p < .01) than for IJV-C. However, there were no significant differences (NS) in complications associated with insertion and CVC-RBSI between IJV-C and EJV-C. There were no significant differences such complications as malposition, oozing or hematoma formation of insertion site, arterial bleeding, nerve damage, pneumothorax, and phlebitis between IJV-C and EJV-C. Moreover, EJV-C was not associated with morbidities such as pneumothorax, arterial bleeding, and nerve damage. Thus the study concluded that EJV-C using Groshong catheters has no severe complications and has the same rates of CVC-RBSI as conventional IJV-C for central venous access.

  2. Diffuse thyroid metastases and bilateral internal jugular vein tumor thrombus from renal cell cancer.

    PubMed

    Jha, Priyanka; Shekhar, Mallika; Wan, Jennifer; Mari-Aparici, Carina

    2016-12-01

    Renal cell cancer rarely metastasizes to the thyroid gland, and it has been reported to present as a solitary mass. We present a case of diffuse thyroid cancer metastases from renal cell cancer. Bilateral internal jugular vein tumor thrombi were also present. To the best of our knowledge, this is the first description of diffuse thyroid metastases from renal cell cancer in the English literature. Renal cell cancer metastases should be considered in the differential of thyroid imaging abnormalities arising in the setting of known renal cell carcinoma, particularly late in the course of disease. This is frequently associated with internal jugular vein thrombi, which should be evaluated with an abnormal thyroid. Thyroglobulin levels are usually normal in such patients.

  3. Non-contact hemodynamic imaging reveals the jugular venous pulse waveform

    PubMed Central

    Amelard, Robert; Hughson, Richard L.; Greaves, Danielle K.; Pfisterer, Kaylen J.; Leung, Jason; Clausi, David A.; Wong, Alexander

    2017-01-01

    Cardiovascular monitoring is important to prevent diseases from progressing. The jugular venous pulse (JVP) waveform offers important clinical information about cardiac health, but is not routinely examined due to its invasive catheterisation procedure. Here, we demonstrate for the first time that the JVP can be consistently observed in a non-contact manner using a photoplethysmographic imaging system. The observed jugular waveform was strongly negatively correlated to the arterial waveform (r = −0.73 ± 0.17), consistent with ultrasound findings. Pulsatile venous flow was observed over a spatially cohesive region of the neck. Critical inflection points (c, x, v, y waves) of the JVP were observed across all participants. The anatomical locations of the strongest pulsatile venous flow were consistent with major venous pathways identified through ultrasound. PMID:28065933

  4. Iliopsoas abscess as a complication of tunneled jugular vein catheterization in a hemodialysis patient.

    PubMed

    Hsiao, Po-Jen; Tsai, Ming-Hsien; Leu, Jyh-Gang; Fang, Yu-Wei

    2015-04-01

    Iliopsoas abscess is a rare complication in hemodialysis patients that is mainly due to adjacent catheterization, local acupuncture, discitis, and bacteremia. Herein, we report a 47-year-old woman undergoing regular hemodialysis via a catheter in the internal jugular vein who presented with low back pain and dyspnea. A heart murmur suggested the presence of catheter-related endocarditis, and this was confirmed by an echocardiogram and a blood culture of methicillin-resistant Staphylococcus aureus. A computed tomography indicated a pulmonary embolism and an incidental finding of iliopsoas abscess. Following surgical intervention and intravenous daptomycin, the patient experienced full recovery and a return to usual activities. This case indicates that an iliopsoas abscess can be related to a jugular vein catheter, which is apparently facilitated by infective endocarditis. The possibility of iliopsoas abscess should be considered when a hemodialysis patient presents with severe low back pain, even when there is no history of adjacent mechanical intervention.

  5. Spinal Accessory Neuropathy Associated With the Tumor Located on the Jugular Foramen

    PubMed Central

    Lee, Soyoung; Lee, Jieun; Kim, Inhwan

    2013-01-01

    Spinal accessory neuropathy is commonly caused by iatrogenic injury or secondary to trauma or infection. Nevertheless, the tumor related palsy is rare. We present a case of an 18-year-old male patient suffering from paralysis of his right trapezius and sternocleidomastoid muscle. An electrophysiologic diagnostic study confirmed the spinal accessory neuropathy of the proximal segment. In addition, magnetic resonance imaging showed the location of tumor on the jugular foramen. However, the type of the tumor was not confirmed through biopsy because the patient refused surgical procedure. Based on the study, it is hypothesized that the tumor located on the jugular foramen should be considered as a cause of the spinal accessory nerve of the proximal segment. PMID:23526381

  6. Non-contact hemodynamic imaging reveals the jugular venous pulse waveform

    NASA Astrophysics Data System (ADS)

    Amelard, Robert; Hughson, Richard L.; Greaves, Danielle K.; Pfisterer, Kaylen J.; Leung, Jason; Clausi, David A.; Wong, Alexander

    2017-01-01

    Cardiovascular monitoring is important to prevent diseases from progressing. The jugular venous pulse (JVP) waveform offers important clinical information about cardiac health, but is not routinely examined due to its invasive catheterisation procedure. Here, we demonstrate for the first time that the JVP can be consistently observed in a non-contact manner using a photoplethysmographic imaging system. The observed jugular waveform was strongly negatively correlated to the arterial waveform (r = ‑0.73 ± 0.17), consistent with ultrasound findings. Pulsatile venous flow was observed over a spatially cohesive region of the neck. Critical inflection points (c, x, v, y waves) of the JVP were observed across all participants. The anatomical locations of the strongest pulsatile venous flow were consistent with major venous pathways identified through ultrasound.

  7. Venous thrombosis in subclavian, axillary, brachial veins with extension to internal jugular vein, right sigmoid sinus and simultaneous pulmonary embolism

    PubMed Central

    Tamizifar, Babak; Beigi, Arash; Rismankarzadeh, Maryam

    2013-01-01

    We present a rare case of Venous Thrombosis in Subclavian, Axillary, Brachial Veins with extension to Internal Jugular vein, right sigmoid sinus and simultaneous Pulmonary embolism during the treatment with low molecular weight heparin. PMID:23901341

  8. Ultrasonographic diagnosis of catheter-induced combined subclavian and internal jugular vein thrombosis.

    PubMed

    Abulafia, O; Sherer, D M; DeEulis, T G

    1995-03-01

    Catheter-induced subclavian and internal jugular vein thrombosis in a patient with unresectable ovarian carcinoma was diagnosed by sonography following subtle clinical symptomatology. Ultrasonographic diagnosis of central vein thrombosis offers applicable, noninvasive bedside diagnosis. The case we describe suggests that a low threshold should be maintained for application of this technique in the diagnosis of this potentially life-threatening complication, especially with the current widespread application of invasive monitoring.

  9. Percutaneous trans-jugular vein closure of atrial septal defect with steerable introducer under echocardiographic guidance

    PubMed Central

    Fang, Jian; Ma, Lunchao; Kuang, Suhua; Lu, Guoliang; Zhang, Yingyuan; Liao, Shengjie

    2015-01-01

    Background The aim of this study is to discuss a novel surgical approach of percutaneous trans-jugular vein closure of atrial septal defect (ASD) with steerable introducer under echocardiographic guidance. Methods From January 2015 to June 2015, ten ASD patients underwent percutaneous trans-jugular vein ASD closure, the occluder placement could be perpendicular to the plane of ASD using the steerable introducer. Results All cases succeeded. The average procedure time was 27.4±5.6 minutes; and the average intracardiac operation time was 6.7±5.2 minutes. No patient showed the residual shunt after the procedure. There was no clinical death, no arrhythmia, no hemolysis, no infection, no jugular vein damage or occlusion during patients’ hospitalization. The post-operation follow up after one month of the operation showed that there was no residual shunt, no falling off or detachment of occluders or other complications. Conclusions It is a new surgical method with easy operation, mild damage and wider indication. Compared with the traditional percutaneous and transthoracic closure of ASD, it has obvious advantages. PMID:26623109

  10. Age-related brain atrophy may be mitigated by internal jugular vein enlargement in male individuals without neurologic disease.

    PubMed

    Belov, Pavel; Magnano, Christopher; Krawiecki, Jacqueline; Hagemeier, Jesper; Bergsland, Niels; Beggs, Clive; Zivadinov, Robert

    2017-03-01

    Objectives To assess the relationship between cross-sectional area of internal jugular veins and brain volumes in healthy individuals without neurologic disease. Methods A total of 193 healthy individuals without neurologic disease (63 male and 130 female; age > 20 to < 70 years) received magnetic resonance venography and structural brain magnetic resonance imaging at 3T. The internal jugular vein cross-sectional area was assessed at C2-C3, C4, C5-C6, and C7-T1. Normalized whole brain volume was assessed. Partial correlation analyses were used to determine associations. Results There was an inverse relationship between normalized whole brain volume and total internal jugular vein cross-sectional area (C7-T1: males r = -0.346, p = 0.029; females r = -0.301, p = 0.002). After age adjustment, association of normalized whole brain volume and normalized gray matter volume with internal jugular vein cross-sectional area became positive in males (normalized whole brain volume and right internal jugular vein cross-sectional area (C2-C3) changed from r = -0.163 to r = 0.384, p = 0.002), but not in the females. Conclusion Sex differences exist in the relationship between brain volume and internal jugular vein cross-sectional area in healthy individuals without neurologic disease.

  11. Concurrent Angioplasty Balloon Placement for Stent Delivery through Jugular Venous Bulb for Treating Cerebral Venous Sinus Stenosis. Technical Report

    PubMed Central

    Qureshi, Adnan I.; Khan, Asif A.; Capistrant, Rachel; Qureshi, Mushtaq H.; Xie, Kevin; Suri, M. Fareed K.

    2016-01-01

    OBJECTIVE To report upon technique of concurrent placement of angioplasty balloon at the internal jugular vein and sigmoid venous sinus junction to facilitate stent delivery in two patients in whom stent delivery past the jugular bulb was not possible. CLINICAL PRESENTATION A 21-year-old woman and a 41-year-old woman with worsening headaches, visual obscuration or diplopia were treated for pseudotumor cerebri associated with transverse venous stenosis. Both patients had undergone primary angioplasty, which resulted in improvement in clinical symptoms followed by the recurrence of symptoms with restenosis at the site of angioplasty. INTERVENTION After multiple attempts at stent delivery through jugular venous bulb were unsuccessful, a second guide catheter was placed in the ipsilateral internal jugular vein through contralateral femoral venous approach. A 6 mm × 20 mm (left) or 5 × 15 mm (right) angioplasty balloon was placed across the internal jugular vein and sigmoid sinus junction and partially inflated until the inflation and relative straightening of the junction was observed. In both patients, the internal jugular vein and sigmoid sinus junction was successfully traversed by the stent delivery system in a parallel alignment to inflated balloon. Balloon mounted stent was deployed at the site of restenosis with near complete resolution of lumen narrowing delivery and improvement in clinical symptoms. CONCLUSION We report a technique for realignment and diameter change with concurrent placement and partial inflation of angioplasty balloon at the jugular venous bulb to facilitate stent delivery into the sigmoid and transverse venous sinuses in circumstances where multiple attempts at stent delivery are unsuccessful. PMID:27829971

  12. An intermediate term benefits and complications of gamma knife surgery in management of glomus jugulare tumor.

    PubMed

    Hafez, Raef F A; Morgan, Magad S; Fahmy, Osama M

    2016-02-15

    Glomus tumors are rare skull base slow-growing, hypervascular neoplasms that frequently involve critical neurovascular structures, and delay in diagnosis is frequent. Surgical removal is rarely radical and is usually associated with morbidity or mortality. Gamma knife surgery (GKS) has gained an increasing dependable role in the management of glomus jugulare tumors, with high rate of tumor growth control, preserving or improving clinical status and with limited complications. This study aims to evaluate intermediate term benefits and complications of gamma knife surgery in management of twenty-two patients bearing growing glomus jugulare tumors at the International Medical Center (IMC), Cairo, Egypt, between 2005 and 2011. The mean follow-up period was 56 months (range 36-108 months); there were 3 males, 19 females; mean age was 43.6 years; 15 patients had GKS as the primary treatment; 2 patients had surgical residuals; 2 had previous radiation therapy; and 3 previously underwent endovascular embolization. The average tumor volume was 7.26 cm3, and the mean marginal dose was 14.7 Gy. Post gamma knife surgery through the follow-up period neurological status was improved in 12 patients, 7 showed stable clinical condition and 3 patients developed new moderate deficits. Tumor volume post GKS was unchanged in 13 patients, decreased in 8, and showed tumor regrowth in 1 patient. Tumor progression-free survival in our studied patients was 95.5% at 5 and 7 years of the follow-up period post GKS. Gamma knife surgery could be used safely and effectively with limited complications as a primary management tool in the treatment of glomus jugulare tumors controlling tumor growth with preserving or improving clinical status especially those who do not have significant cranial or cervical extension, elderly, and surgically unfit patients; moreover, it is safe and highly effective as adjuvant therapy as well.

  13. In Vitro MRV-based Hemodynamic Study of Complex Helical Flow in a Patient-specific Jugular Model

    NASA Astrophysics Data System (ADS)

    Kefayati, Sarah; Acevedo-Bolton, Gabriel; Haraldsson, Henrik; Saloner, David

    2014-11-01

    Neurointerventional Radiologists are frequently requested to evaluate the venous side of the intracranial circulation for a variety of conditions including: Chronic Cerebrospinal Venous Insufficiency thought to play a role in the development of multiple sclerosis; sigmoid sinus diverticulum which has been linked to the presence of pulsatile tinnitus; and jugular vein distension which is related to cardiac dysfunction. Most approaches to evaluating these conditions rely on structural assessment or two dimensional flow analyses. This study was designed to investigate the highly complex jugular flow conditions using magnetic resonance velocimetry (MRV). A jugular phantom was fabricated based on the geometry of the dominant jugular in a tinnitus patient. Volumetric three-component time-resolved velocity fields were obtained using 4D PC-MRI -with the protocol enabling turbulence acquisition- and the patient-specific pulsatile waveform. Flow was highly complex exhibiting regions of jet, high swirling strength, and strong helical pattern with the core originating from the focal point of the jugular bulb. Specifically, flow was analyzed for helicity and the level of turbulence kinetic energy elevated in the core of helix and distally, in the post-narrowing region.

  14. Non-cuffed dual lumen catheters in the external jugular veins versus other central veins for hemodialysis patients.

    PubMed

    Moini, Majid; Rasouli, Mohammad R; Kenari, Mohammad Mahmoodzadeh; Mahmoodi, Hamid Reza

    2009-01-01

    To compare prospective between insertion of non-cuffed dual lumen catheter in the external jugular vein and other central veins for hemodialysis (HD), we studied 68 chronic dialysis patients randomly allocated into two groups: one with external jugular vein catheterization as access for HD and another with other central venous catheterization, internal jugular or subclavian vein. Our results showed there were no significant differences regarding successful cannulation, com-plications, total numbers of dialysis, development of pain and infection at the site of cannulation, patency rate of the catheters, and efficacy of hemodialysis between both groups. In addition, the patency of the catheter in the external jugular vein was not affected by previous cannulation of other central veins. In contrast, there was a significant correlation between numbers of attempts for cannulation in both groups and development of hematoma and infection, (p< 0.05). In conclusion, our results showed that the external jugular vein may be an alternative for other central veins for insertion of temporary non-cuffed hemodialysis catheter.

  15. Hyperhomocysteinemia and left internal jugular vein thrombosis with Ménière's symptom complex.

    PubMed

    Scaramella, John G

    2003-11-01

    The author describes the case of a 68-year-old woman who experienced severe symptoms of Ménière's syndrome. Ultrasonography of the neck detected a clot in the left internal jugular vein. The patient was hospitalized and anticoagulated, and her symptoms soon resolved. The author speculates that the clot-induced hemodynamic changes led to venous insufficiency in the vein of the paravestibular canaliculus and ultimately caused the patient's symptoms. The blood work-up revealed that the patient had an elevated fasting homocysteine level, which is a known risk factor for thrombus formation.

  16. Assessing techniques for disinfecting sites for inserting intravenous catheters into the jugular veins of horses.

    PubMed

    Geraghty, T E; Love, S; Taylor, D J; Heller, J; Mellor, D J; Hughes, K J

    2009-01-10

    The sites of insertion of catheters into the jugular veins of six horses were investigated to determine common isolates and to assess the effectiveness of two disinfection protocols with the hair coat left long, clipped or shaved. Skin commensals (Staphylococcus, Streptococcus and Micrococcus species) and environmental contaminants (Bacillus, Enterobacteriaceae, Aspergillus and Mucor species) were the microorganisms most frequently isolated. Chlorhexidine gluconate and povidone-iodine-based skin disinfection protocols resulted in significant reductions in the number of bacterial isolates from clipped sites. With chlorhexidine, there were no significant differences between the reductions observed at sites with the hair coat left long, clipped or shaved.

  17. Isolated glossopharyngeal and vagus nerves palsy due to fracture involving the left jugular foramen.

    PubMed

    Alberio, N; Cultrera, F; Antonelli, V; Servadei, F

    2005-07-01

    This report describes a case of delayed post-traumatic glossopharyngeal and vagus nerves palsy (i.e. dysphonia and swallowing dysfunction). A high resolution CT study of the cranial base detected a fracture rim encroaching on the left jugular foramen. Treatment consisted in supportive measures with incomplete recovery during a one-year follow-up period. Lower cranial nerves palsies after head trauma are rare and, should they occur, a thorough investigation in search of posterior cranial base and cranio-cervical lesions is warranted. The presumptive mechanism in our case is a fracture-related oedema and ischemic damage to the nerves leading to the delayed occurrence of the palsy.

  18. Achondrogenesis type II (Langer-Saldino) in association with jugular lymphatic obstruction sequence.

    PubMed

    Wenstrom, K D; Williamson, R A; Hoover, W W; Grant, S S

    1989-07-01

    The prenatal diagnosis of achondrogenesis in association with cystic hygroma is described. Ultrasound findings of severe short-limbed dwarfism, decreased vertebral ossification, and normal ossification of the calvarium were all consistent with achondrogenesis type II. Although the unusual finding of associated cystic hygroma raised the suspicion of a concurrent chromosome abnormality, the karyotype of both fetal lymphocytes and fetal fibroblasts was normal. Autopsy confirmed dilated lymphatic channels in the basal endothelial layer of the skin, cystic hygroma, and coarctation of the aorta. Although previously unreported, we suggest that the features of this case of achondrogenesis indicate an association with lymphatic stasis and jugular lymphatic obstruction sequence in this syndrome.

  19. A novel method to estimate oxygen saturation of the internal jugular vein blood

    NASA Astrophysics Data System (ADS)

    Li, Kai; Pan, Boan; Gao, Yuan; Ruan, Zhengshang; Li, Ting

    2016-03-01

    This article introduces a novel method to estimate oxygen saturation of the internal jugular vein blood (SjvO2) by using Near Infrared spectroscopy (NIRS). The different positions of patients can affect the cross-sectional area (CSA) of the internal jugular vein (IJV), in other words, it causes the sectional change of the IJV blood volume. When lying position of patients, the CSA is larger than that keeping upper body 80 degree, and the CSA can compute quantitatively by the use of ultrasound and digital image processing methods. The entire method consist of constructing different position of patient (upper body rotation 0 and 80 degree), comparing the light absorption changes. SjvO2 has been determined from light absorption measurements in two wavelength, before and after the position changes. The method has been applied to the vertical area over the IJV of 11 patients who were placed a central venous catheter into a large vein in the neck for medical uses, using wavelength of 735 and 850 nm. At last, comparing the SjvO2NIRS which measured by NIRS noninvasively with SjvO2IJVBG which was quantified using a whole blood gas analyzer, we found there were some certain relativity. The results were influenced by vascular depth greatly.

  20. Internal Jugular and Subclavian Vein Thrombosis in a Case of Ovarian Cancer

    PubMed Central

    Hayama, Nana; Morozumi, Shouko; Nakano, Mika; Nakayama, Akari; Takahata, Yoshiomi; Sakaguchi, Yuusuke; Inoue, Natsuki; Kubota, Toshiki; Takenoya, Akiko; Ishii, Yoshiko; Okubo, Haruka; Yamaguchi, Souta; Ono, Tsuyoshi; Oharaseki, Toshiaki; Yoshikawa, Mamoru

    2017-01-01

    Central venous catheter insertion and cancer represent some of the important predisposing factors for deep venous thrombosis (DVT). DVT usually develops in the lower extremities, and venous thrombosis of the upper extremities is uncommon. Early diagnosis and treatment of deep venous thrombosis are of importance, because it is a precursor of complications such as pulmonary embolism and postthrombotic syndrome. A 47-year-old woman visited our department with painful swelling on the left side of her neck. Initial examination revealed swelling of the region extending from the left neck to the shoulder without any redness of the overlying skin. Laboratory tests showed a white blood cell count of 5,800/mm3 and an elevated serum C-reactive protein of 4.51 mg/dL. Computed tomography (CT) of the neck revealed a vascular filling defect in the left internal jugular vein to left subclavian vein region, with the venous lumina completely occluded with dense soft tissue. On the basis of the findings, we made the diagnosis of thrombosis of the left internal jugular and left subclavian veins. The patient was begun on treatment with oral rivaroxaban, but the left shoulder pain worsened. She was then admitted to the hospital and treated by balloon thrombectomy and thrombolytic therapy, which led to improvement of the left subclavian venous occlusion. Histopathologic examination of the removed thrombus revealed adenocarcinoma cells, indicating hematogenous dissemination of malignant cells. PMID:28194291

  1. Collet-Sicard Syndrome from Thrombosis of the Sigmoid-Jugular Complex: A Case Report and Review of the Literature

    PubMed Central

    Handley, Tom P. B.; Miah, Mohammed S.; Majumdar, Samit; Hussain, S. S. Musheer

    2010-01-01

    Purpose. Collet-Sicard syndrome is a very rare condition characterised by unilateral palsy of the IX–XII cranial nerves. It is distinguished from Villaret syndrome by lack of presence of sympathetic involvement. Current literature contains only two cases of Collet-Sicard syndrome due to idiopathic internal jugular vein thrombosis. Method and Results. We report the case of Collet-Sicard syndrome in a 30-year-old man who presented with delayed development of XIth nerve dysfunction, due to internal jugular vein-sigmoid sinus thrombosis. A multidisciplinary team approach was employed in the management of this patient. At three-month followup, he had significantly improved swallowing, and repeat computed tomography neck scan showed partial recanalisation of the right internal jugular vein. Conclusion. In suspected Collet-Sicard syndrome, a focal primary lesion or metastasis to the temporal bone must be excluded, and sigmoid-jugular complex thrombosis should be considered in the differential diagnosis. Early recognition and treatment may result in significant functional recovery. PMID:20706543

  2. Successful percutaneous transcatheter patent foramen ovale closure through the right internal jugular vein using a steerable catheter.

    PubMed

    Hascoet, Sebastien; Fraisse, Alain; Elbaz, Meyer

    2013-10-01

    Percutaneous transcatheter closure of a patent foramen ovale (PFO) remains challenging when femoral venous approach is not available. We describe the successful closure of a PFO using the right internal jugular venous approach and a deflectable catheter delivery system in a patient with a PFO, recurrent stroke, and an inferior vena cava filter.

  3. Why Current Doppler Ultrasound Methodology Is Inaccurate in Assessing Cerebral Venous Return: The Alternative of the Ultrasonic Jugular Venous Pulse

    PubMed Central

    2016-01-01

    Assessment of cerebral venous return is growing interest for potential application in clinical practice. Doppler ultrasound (DUS) was used as a screening tool. However, three meta-analyses of qualitative DUS protocol demonstrate a big heterogeneity among studies. In an attempt to improve accuracy, several authors alternatively measured the flow rate, based on the product of the time average velocity with the cross-sectional area (CSA). However, also the quantification protocols lacked of the necessary accuracy. The reasons are as follows: (a) automatic measurement of the CSA assimilates the jugular to a circle, while it is elliptical; (b) the use of just a single CSA value in a pulsatile vessel is inaccurate; (c) time average velocity assessment can be applied only in laminar flow. Finally, the tutorial describes alternative ultrasound calculation of flow based on the Womersley method, which takes into account the variation of the jugular CSA overtime. In the near future, it will be possible to synchronize the electrocardiogram with the brain inflow (carotid distension wave) and with the outflow (jugular venous pulse) in order to nicely have a noninvasive ultrasound picture of the brain-heart axis. US jugular venous pulse may have potential use in neurovascular, neurocognitive, neurosensorial, and neurodegenerative disorders. PMID:27006525

  4. Perinatal autopsy findings in three cases of jugular lymphatic obstruction sequence and cardiac polyvalvular dysplasia.

    PubMed

    Bendon, Robert; Asamoah, Alexander

    2008-01-01

    Three infants with a prenatal diagnosis of Noonan's syndrome suffered fetal hydrops and immediate neonatal death. The infants all had the external appearance of jugular lymphatic obstruction sequence with wide-spaced nipples, redundant posterior nuchal skin, and edema of the dorsa of the feet and hands. All 3 demonstrated thick, redundant leaflets of all 4 cardiac valves, and 2 had a membranous ventricular septal defect. One female infant had a mutation of the PTPN11 gene. Two males had no common mutation of PTPN11. The males demonstrated other abnormalities in common, including small penis, testicular malformation, rosette-like appearance of the pituicytes, and an eosinophil infiltration of the pancreatic islets with islet cell hypertrophy. Detailed anatomy of cases of lymphatic obstruction sequence fetuses can be correlated with an increasing number of genetic mutations associated with Noonan's syndrome and related syndromes in mice and humans.

  5. External Carotid-Internal Jugular Fistula as a Late Complication After Carotid Endarterectomy: A Rare Case

    SciTech Connect

    Bakar, Bulent; Cekirge, Saruhan; Tekkok, Ismail Hakki

    2011-02-15

    A 66-year-old man presented with mild amnesia, progressive fatigue, ataxia, visual hallucinations, and debility. His past medical history included right-sided carotid endarterectomy performed elsewhere 6 years previously. Cranial magnetic resonance imaging showed left parieto-occipital arteriovenous malformation-like tortous vessels, venous congestion, and ischemic areas. Cerebral angiography showed right-sided compound external carotid artery-internal jugular vein (IJV) fistula, and distal occlusion of the right IJV. Transvenous embolization via contralateral IJV was performed, and the fistula, together with fistulous portion of the distal IJV, was sealed using coils. Two years later, patient is well with normal neurologic examination findings. The presence of an arteriovenous communication after vascular surgery is a serious complication with potential long-term effects and therefore should be diagnosed and treated as promptly as possible.

  6. Accidental arterial puncture during right internal jugular vein cannulation in cardiac surgical patients

    PubMed Central

    Maddali, Madan Mohan; Arun, Venkitaramanan; Wala, Al-Ajmi Ahmed; Al-Bahrani, Maher Jaffer; Jayatilaka, Cheskey Manoj; Nishant, Arora Ram

    2016-01-01

    Background: The primary aim of this study was to compare the incidence of accidental arterial puncture during right internal jugular vein (RIJV) cannulation with and without ultrasound guidance (USG). The secondary end points were to assess if USG improves the chances of successful first pass cannulation and if BMI has an impact on incidence of arterial puncture and the number of attempts that are to be made for successful cannulation. Settings and Design: Prospective observational study performed at a single tertiary cardiac care center. Material and methods: 255 consecutive adult and pediatric cardiac surgical patients were included. In Group I (n = 124) USG was used for the right internal jugular vein cannulation and in Group II (n = 81) it was not used. There were 135 adult patients and 70 pediatric patients. Statistical analysis: Demographic and categorical data were analyzed using Student ‘t’ test and chi- square test was used for qualitative variables. Results: The overall incidence of accidental arterial puncture in the entire study population was significantly higher when ultrasound guidance was not used (P < 0.001). In subgroup analysis, incidence of arterial puncture was significant in both adult (P = 0.03) and pediatric patients (P < 0.001) without USG. First attempt cannulation was more often possible in pediatric patients under USG (P = 0.03). In adult patients USG did not improve first attempt cannulation except in underweight patients. Conclusions: USG helped in the avoidance of inadvertent arterial puncture during RIJV cannulation and simultaneously improved the chances of first attempt cannulation in pediatric and in underweight adult cardiac surgical patients. PMID:27716688

  7. [Prevalence of stenosis and thrombosis of central veins in hemodialysis after a tunneled jugular catheter].

    PubMed

    Jean, G; Vanel, T; Chazot, C; Charra, B; Terrat, J C; Hurot, J M

    2001-01-01

    Central venous stenosis (ST) and thrombosis (TB) related to catheter (KT) had been reported mostly for the subclavian vein. We performed a systematic cavographic study to evaluate the prevalence of these complications in 51 hemodialysis patients with present or previous history of tunneled internal jugular catheter. Each of them had used one or several KT (1.8 +/- 1.4 KT) for a mean 28 +/- 26 month cumulative time (i.e. 43,584 days total exposure time). Fifty percent of the KT were PermCath Quinton and 50% were Twincath (uncuffed) or CS 100 (cuffed) Medcomp. Twenty-seven had no ST (53%, group I), 24 had one or several significant ST (47%, group II) of superior Vena Cava (SVC, n = 4), inferior Vena Cava (IVC, n = 1), Brachio-cephalic Vein (BCV, n = 5) and subclavian vein (SC, n = 10), or a TB of SVC (n = 1), IVC (n = 3), BCV (n = 3), SC (n = 2). This accounts for an incidence of 0.55 ST or TB/1000 patient-days. Five of the twelve subclavian ST and TB had no history of previous subclavian catheter. Comparison between the two groups showed no differences according to age, time on dialysis, diabetes, hematocrit, CRP, cumulative time with catheter, catheter-related infections, type of catheter and anticoagulant treatment. IVC catheter tip's position is an important risk factor for TB and ST (4/6). Twelve group II patients had ST or TB-related symptoms, with a functional AV fistula in 9 cases. Eleven patients underwent repeated percutaneous angioplasty with 4 additional Wallstents and in 2 cases an AV fistula need to be closed. Central venous ST and TB after a jugular KT is extremely frequent, mostly without any symptoms. Consequences on peripheral or central vascular access, cost and poor long-term patency rate of angioplasty are of major importance. These results incite us to further reduce the catheter use in dialysis patients.

  8. Jugular venous 'a' wave in dilated cardiomyopathy: sign of abbreviated right ventricular filling time.

    PubMed Central

    Lee, C H; Xiao, H B; Gibson, D G

    1991-01-01

    OBJECTIVE--To study the mechanisms underlying the high venous pressure often seen in patients with dilated cardiomyopathy. DESIGN--Retrospective and prospective examination of the pattern of flow in the superior vena cava, cardiac echo-Doppler studies, and recordings of the jugular venous pulse. SETTING--A tertiary referral cardiac centre. PATIENTS PARTICIPANTS--23 patients with dilated cardiomyopathy, all with functional mitral and tricuspid regurgitation. RESULTS--Two patterns of venous pulse were seen: a dominant 'a' wave and 'x' descent, with systolic flow in the superior vena cava (group 1, n = 11), and a dominant 'v' wave with 'y' descent and diastolic flow in the superior vena cava (group 2, n = 12). A comparison of group 1 and group 2 showed: age (mean (SD] 58 (12) v 61 (6) years, left ventricular end diastolic dimension 7.0 (0.7) cm in both groups, right ventricular short axis 3.3 (0.6) v 3.6 (0.5) cm and long axis 7.3 (0.5) v 7.1 (0.7) cm, and duration of tricuspid regurgitation 350 (65) v 370 (50) ms. The RR interval (550 (100) v 680 (80) ms) and right ventricular filling time (150 (30) v 290 (50) ms) were significantly shorter in group 1. In all patients in group 2 right ventricular filling time was more than 200 ms with separate E and A waves on the tricuspid Doppler echocardiogram, while in all group 1 patients it was less than 200 ms with a single summation peak. In nine patients in group 1, the right ventricular filling time was limited by prolonged tricuspid regurgitation and in the remaining two by prolonged isovolumic relaxation time (215 (80) ms), so that it was consistently significantly less than that of the left ventricle. CONCLUSION--In patients with dilated cardiomyopathy, right ventricular filling time may be so short that it limits stroke volume. Such patients can be recognised by a dominant 'a' wave on the jugular venous pulse. Patients in whom the right ventricular filling time was longer showed a dominant 'v' wave. Both groups can

  9. [Two Cases of Retained Guide Wires after Placement of a Central Venous Catheter via the Internal Jugular Vein].

    PubMed

    Kobayashi, Yuki; Masumori, Yasushi; Tanigawa, Saori; Miyakawa, Hidetoshi; Sakamoto, Miki; Tateda, Takeshi

    2015-10-01

    We report two cases of a retained guide wire after perioperative placement of a central venous catheter during a six-month period. Case 1: A 73-year-old male was scheduled for an open cholecystectomy and hepatectomy. After induction of anesthesia, a central venous (CV) catheter was inserted via the right internal jugular vein using an ultrasound guide. Chest radiographs showed a retained guide wire in the inferior vena cava immediately after surgery, which was removed by interventional radiologist before the patient emerged from anesthesia. Case 2: A 77-year-old male was scheduled for colostomy closure. The surgeon inserted a CV catheter in the right internal jugular vein 4 days before the colostomy. Chest radiographs revealed a retained guide wire in the inferior vena cava, which was removed by interventional radiologists before the patient emerged from anesthesia. Although a retained guide wire is a rare complication, awareness of this mishap is necessary to prevent it from happening.

  10. To reduce catheter-related bloodstream infections: is the subclavian route better than the jugular route for central venous catheterization?

    PubMed

    Nagashima, Goro; Kikuchi, Toshiki; Tsuyuzaki, Hitomi; Kawano, Rumiko; Tanaka, Hiroyuki; Nemoto, Hiroshi; Taguchi, Kazumi; Ugajin, Kazuhisa

    2006-12-01

    The most important targets of hospital-acquired infection control are to reduce the incidence of surgical-site, catheter-related, and ventilator-associated infections. In this report, we address previously presented infection-control strategies for central venous (CV) line catheterization, using a CV catheter-related infection surveillance system. Data concerning CV catheter insertion were collected from all facilities in our 650-bed hospital, excluding the operating and hemodialysis wards. Collected data included the insertion method, purpose, length of catheter inserted, duration of catheterization, infection rate, and complication rate. Catheter-related infection was diagnosed based on bacteriological examinations from blood cultures. The total number of catheterizations was 806 a year, and average duration of catheterization was 9.8 days. The purpose of catheterization was nutritional support in 210 cases, hemodialysis in 96 cases, cardiac support in 174 cases, and other treatments in 260 cases. In 66 cases, the purpose of CV catheter was not specified. The rate of positive cultures was 7.1%, and complications other than infection occurred in 0.5%. The main causative organisms were methicillin-resistant Staphylococcus aureus (MRSA) in 38.6%, coagulase-negative Staphylococcus epidermidis (CNS) in 33.3%, and S. aureus in 12.3% of infections. Infection rates were 3.8 per 1000 catheter-days in subclavian, 6.1 in jugular, and 15.7 in femoral vein catheterization. In high-risk departments (intensive care unit [ICU] and emergency departments) the infection rate was 5.4 for subclavian and 10.2 for jugular catheterization, whereas it was 3.6 for subclavian and 4.6 for jugular catheterization in noncritical-care departments. Considering complications such as pneumothorax, CV catheterization of the jugular vein is recommended in certain situations.

  11. The measurement of tissue interface pressures and changes in jugular venous parameters associated with cervical immobilisation devices: a systematic review.

    PubMed

    Sparke, Alison; Voss, Sarah; Benger, Jonathan

    2013-12-03

    Cervical immobilisation is commonly applied following trauma, particularly blunt head injury, but current methods of immobilisation are associated with significant complications. Semi-rigid disposable cervical collars are known to cause pressure ulcers, and impede effective airway management. These collars may also exacerbate a head injury by increasing intracranial pressure as a result of external compression of the jugular veins. There is a clear imperative to find ways of effectively immobilising the cervical spine whilst minimising complications, and any assessment of existing or new devices should include a standardized approach to the measurement of tissue interface pressures and their effect on jugular venous drainage from the brain. This systematic review summarises the research methods and technologies that have been used to measure tissue interface pressure and assess the jugular vein in the context of cervical immobilisation devices. 27 papers were included and assessed for quality. Laboratory investigations and biomechanical studies have gradually given way to methods that more accurately reflect clinical care. There are numerous accounts of skin ulceration associated with cervical collars, but no standardised approach to measuring tissue interface pressure. It is therefore difficult to compare studies and devices, but a pressure of less than 30 mmHg appears desirable. Cervical collars have been shown to have a compressive effect on the jugular veins, but it is not yet certain that this is the cause of the increased intracranial pressure observed in association with cervical collar use. This is the first review of its type. It will help guide further research in this area of trauma care, and the development and testing of new cervical immobilisation devices.

  12. The measurement of tissue interface pressures and changes in jugular venous parameters associated with cervical immobilisation devices: a systematic review

    PubMed Central

    2013-01-01

    Cervical immobilisation is commonly applied following trauma, particularly blunt head injury, but current methods of immobilisation are associated with significant complications. Semi-rigid disposable cervical collars are known to cause pressure ulcers, and impede effective airway management. These collars may also exacerbate a head injury by increasing intracranial pressure as a result of external compression of the jugular veins. There is a clear imperative to find ways of effectively immobilising the cervical spine whilst minimising complications, and any assessment of existing or new devices should include a standardized approach to the measurement of tissue interface pressures and their effect on jugular venous drainage from the brain. This systematic review summarises the research methods and technologies that have been used to measure tissue interface pressure and assess the jugular vein in the context of cervical immobilisation devices. 27 papers were included and assessed for quality. Laboratory investigations and biomechanical studies have gradually given way to methods that more accurately reflect clinical care. There are numerous accounts of skin ulceration associated with cervical collars, but no standardised approach to measuring tissue interface pressure. It is therefore difficult to compare studies and devices, but a pressure of less than 30 mmHg appears desirable. Cervical collars have been shown to have a compressive effect on the jugular veins, but it is not yet certain that this is the cause of the increased intracranial pressure observed in association with cervical collar use. This is the first review of its type. It will help guide further research in this area of trauma care, and the development and testing of new cervical immobilisation devices. PMID:24299024

  13. A rapid and non-surgical procedure for jugular catheterization of pigs.

    PubMed

    Matte, J J

    1999-07-01

    A rapid and non-surgical method for jugular catheterization in pigs was set up in 30 piglets of 6.2 kg, 23 pigs of 46 kg and 84 kg and two lactating multiparous sows. The animal was restrained on a V-shaped table (piglets) or with a rope around the mandible (slaughter pigs and sows). The vein was located with the Vacutainer system and a wire guide was inserted into the Vacutainer needle up to the vein lumen. When the needle was removed, the catheter was inserted over the wire guide and advanced until it penetrated the skin and thereafter, the vein wall. The catheter was fixed outside by a large tape and coiled inside a patch just behind the ears. The technique utilizes readily available material and is no more risky for the animal than a single blood sampling. Moreover, it can be performed within 15 to 20 min (including animal restraint) within pens. This new approach might have important implications not only for research purposes by facilitating repeated blood samplings but also for projects which require a rapid and easy method for testing of any kind of pharmaceutical or other type of products under husbandry conditions.

  14. The Oscillating Component of the Internal Jugular Vein Flow: The Overlooked Element of Cerebral Circulation

    PubMed Central

    Sisini, Francesco; Toro, Eleuterio; Gambaccini, Mauro; Zamboni, Paolo

    2015-01-01

    The jugular venous pulse (JVP) provides valuable information about cardiac haemodynamics and filling pressures and is an indirect estimate of the central venous pressure (CVP). Recently it has been proven that JVP can be obtained by measuring the cross-sectional area (CSA) of the IJV on each sonogram of an ultrasound B-mode sonogram sequence. It has also been proven that during its pulsation the IJV is distended and hence that the pressure gradient drives the IJV haemodynamics. If this is true, then it will imply the following: (i) the blood velocity in the IJV is a periodic function of the time with period equal to the cardiac period and (ii) the instantaneous blood velocity is given by a time function that can be derived from a flow-dynamics theory that uses the instantaneous pressure gradient as a parameter. The aim of the present study is to confirm the hypothesis that JVP regulates the IJV blood flow and that pressure waves are transmitted from the heart toward the brain through the IJV wall. PMID:26783380

  15. Physical stress testing of bovine jugular veins using magnetic resonance imaging, echocardiography and electrical velocimetry.

    PubMed

    Boethig, Dietmar; Ernst, Franziska; Sarikouch, Samir; Norozi, Kambiz; Lotz, Joachim; Opherk, Jan Patrick; Meister, Maren; Breymann, Thomas

    2010-06-01

    Bovine jugular veins (BJVs) (Contegra) are valve-bearing pulmonary artery substitutes. Their valves have higher profiles than human pulmonary valves; this might result in less optimal performance. Therefore, we investigated the impact of stress and undersizing on conduit performance with ergometry, echocardiography and magnetic resonance imaging (MRI). Between April 2007 and June 2008, 20 BJV recipients (age 7.9-19.6 years) underwent spiroergometry and subsequent echocardiography; after due rest, ergometry was repeated and followed by MRI during recovery. A year later, exams were repeated. Data was evaluated as follows: comparison of stress related maximal individual valve performance changes (magnetic resonance: exercise induced average stroke volume changes by 61+/-49%; mean insufficiency increased by 2% in patients with <1% rest insufficiency and by 8% after rest insufficiency of >10%; the average rest gradient of 24+/-11 mmHg rose to 40+/-20 mmHg), and stratification of pooled observations by regurgitation fraction, insufficiency grades and z-values (insufficiency rose with increasing heart rate and decreasing stroke volume; undersizing increased gradients during recovery by 7+/-0.7 mmHg/z-value). Contegras high-profile valves tolerate stress without performance drop. Stress induced changes of insufficiency and gradient were clinically not significant, but sufficient to distort examination results; therefore, constant examination conditions are indispensable for a correct follow-up.

  16. Internal jugular versus subclavian vein catheterization for central venous catheterization in orthotopic liver transplantation.

    PubMed

    Torgay, A; Pirat, A; Candan, S; Zeyneloglu, P; Arslan, G; Haberal, M

    2005-09-01

    The aim of this study was to compare incidence rates of mechanical and infectious complications associated with central venous catheterization via the internal jugular vein (IJV) versus the subclavian vein (SV) among 45 consecutive patients undergoing orthotopic liver transplantation (OLT) between January 2000 and June 2004. The subjects were divided into two groups according to the site of central venous catheterization (IJV or SV). We recorded each patient's physical characteristics, international normalized ratio (INR), partial thromboplastin time, platelet levels, number of puncture attempts, success/failure of central venous catheterization, duration of catheter placement, occurrence of catheter tip misplacement, arterial puncture, incidence of hematoma or pneumothorax, catheter-related infection, or bacterial colonization of the catheter. Senior staff anesthesiologists performed 22 SV and 23 IJV catheterizations for the 45 OLT procedures. The SV and IVJ groups both had minor coagulation abnormalities with slightly increased INR values at the time of catheterization. There were no significant differences between the groups with respect to success of central venous catheterization (100% for both), numbers of attempted punctures, duration of catheter placement, and incidence rates of mechanical and infectious complications. Both groups showed high frequencies of catheter tip misplacement, with right atrium as the site of misplacement in all cases. Two patients in the IJV group (8.7%) developed hematomas after accidental carotid artery puncture. The results suggest that, when performed by experienced anesthesiologists, central venous catheterization via the SV is an acceptable alternative to IJV catheterization for patients undergoing OLT.

  17. Acute jugular vein thrombosis during rituximab administration: Review of the literature.

    PubMed

    Dada, Reyad; Zekri, Jamal; Ramal, Bilal; Ahmad, Kamel

    2016-02-01

    Rituximab, a chimeric monoclonal antibody is licensed for the treatment of CD20 positive lymphomas. Previous studies have found rituximab, in combination with cyclophosphamide, doxorubicin, vincristine, and prednisone chemotherapy, is superior to cyclophosphamide, doxorubicin, vincristine, and prednisone alone in the treatment of diffuse large B-cell lymphoma and many other B-cell lymphomas. Acute hypersensitivity reactions have been reported in patients receiving rituximab infusion and usually manifesting as headache, fever, chills, sweats, skin rash, dyspnea, mild hypotension, and nausea. Acute major venous thrombosis and seizures have not been reported as manifestation of acute hypersensitivity reaction. We report on a 22-year-old woman, who was diagnosed with stage III B CD20 positive B-cell diffuse large B-cell lymphoma. During the first cycle of treatment, she developed grand-mal seizure while receiving rituximab infusion without any other features of acute hypersensitivity reaction. Imaging confirmed new onset jugular vein thrombosis with normal coagulation parameters. These events were managed by anticonvulsants and anticoagulation therapy. The patient completed eight cycles of cyclophosphamide, doxorubicin, vincristine, and prednisone without rituximab and achieved complete remission. No further complications were noted. To our knowledge, this is the first case in the literature describing grand-mal seizures and acute thrombosis while on rituximab treatment. Clinicians should be aware of this rare side effect, as stopping rituximab can prevent recurrence of these complications.

  18. Right Internal Jugular Vein Cannulation: Carotid Artery-directed versus Sternocleidomastoid-directed Methods.

    PubMed

    Yu, Zhao-Yan; Yuan, Ping; Pan, Yang; Zhang, Zhong-Min

    2016-02-01

    The aim of the present study was to explore a simple and safe method for central venous catheterization (CVC) from the right internal jugular vein (RIJV) by comparing carotid artery (CA) positioning with sternocleidomastoid (SCM) positioning. The medical records of patients who underwent CVC between January 2011 and January 2015 were retrospectively reviewed. Central venous catheters were inserted into the RIJV either above the level of the cricoid cartilage using the CA-directed method (419 patients, Group 1) or below the level of the cricoid cartilage using the SCM-directed method (436 patients, Group 2). Success rate and related complications of catheterization were evaluated in the two groups. The total success rate of RIJV cannulation in Group 1 (97.2%) was higher than that in Group 2 (94.5%). Moreover, the success rate at first attempt was significantly higher in Group 1 than in Group 2 (92.4% vs 86.9%). The incidence of hematoma was 1.6 per cent in Group 1 and 3.8 per cent in Group 2. The rate of other complications such as pneumothorax, catheter-related infections, and catheter occlusion did not significantly differ between the groups. In conclusions, CA-directed RIJV cannulation is more effective and simple to perform than the SCM-directed method, and should become the preferred CVC technique in the absence of ultrasound guidance.

  19. Assessment of Internal Jugular Vein Size in Healthy Subjects with Magnetic Resonance and Semiautomatic Processing

    PubMed Central

    Pelizzari, L.; Scaccianoce, E.; Dipasquale, O.; Ricci, C.; Baglio, F.; Cecconi, P.; Baselli, G.

    2016-01-01

    Background and Objectives. The hypothesized link between extracranial venous abnormalities and some neurological disorders awoke interest in the investigation of the internal jugular veins (IJVs). However, different IJV cross-sectional area (CSA) values are currently reported in literature. In this study, we introduced a semiautomatic method to measure and normalize the CSA and the degree of circularity (Circ) of IJVs along their whole length. Methods. Thirty-six healthy subjects (31.22 ± 9.29 years) were recruited and the 2D time-of-flight magnetic resonance venography was acquired with a 1.5 T Siemens scanner. The IJV were segmented on an axial slice, the contours were propagated in 3D. Then, IJV CSA and Circ were computed between the first and the seventh cervical levels (C1–C7) and normalized among subjects. Inter- and intrarater repeatability were assessed. Results. IJV CSA and Circ were significantly different among cervical levels (p < 0.001). A trend for side difference was observed for CSA (larger right IJV, p = 0.06), but not for Circ (p = 0.5). Excellent inter- and intrarater repeatability was obtained for all the measures. Conclusion. This study proposed a reliable semiautomatic method able to measure the IJV area and shape along C1–C7, and suitable for defining the normality thresholds for future clinical studies. PMID:27034585

  20. Assessment of Internal Jugular Vein Size in Healthy Subjects with Magnetic Resonance and Semiautomatic Processing.

    PubMed

    Laganà, M M; Pelizzari, L; Scaccianoce, E; Dipasquale, O; Ricci, C; Baglio, F; Cecconi, P; Baselli, G

    2016-01-01

    Background and Objectives. The hypothesized link between extracranial venous abnormalities and some neurological disorders awoke interest in the investigation of the internal jugular veins (IJVs). However, different IJV cross-sectional area (CSA) values are currently reported in literature. In this study, we introduced a semiautomatic method to measure and normalize the CSA and the degree of circularity (Circ) of IJVs along their whole length. Methods. Thirty-six healthy subjects (31.22 ± 9.29 years) were recruited and the 2D time-of-flight magnetic resonance venography was acquired with a 1.5 T Siemens scanner. The IJV were segmented on an axial slice, the contours were propagated in 3D. Then, IJV CSA and Circ were computed between the first and the seventh cervical levels (C1-C7) and normalized among subjects. Inter- and intrarater repeatability were assessed. Results. IJV CSA and Circ were significantly different among cervical levels (p < 0.001). A trend for side difference was observed for CSA (larger right IJV, p = 0.06), but not for Circ (p = 0.5). Excellent inter- and intrarater repeatability was obtained for all the measures. Conclusion. This study proposed a reliable semiautomatic method able to measure the IJV area and shape along C1-C7, and suitable for defining the normality thresholds for future clinical studies.

  1. [Effect of catheter type on the functional survival of jugular access ports in chronic hemodialysis].

    PubMed

    Chazot, C; Charra, B; Vanel, T; Jean, G; Laurent, G

    1994-01-01

    Silicone catheter (C) can be used in the hemodialysis setting as an alternative for the blood access. We analysed retrospectively the 3 types of the catheters used in 45 patients. 58 catheters were percutaneously inserted in the internal jugular vein (9 Bard (B)-Hickman; 17 Canaud (CD)-Vygon; 32 Permcath (PC)-Quinton). The indications were thrombosis or dysfunction of an arterio-venous fistula (A-V F) (52%), absence of a A-V F (21%), Thomas' shunt infection (8%), infection or extrusion of a previous catheter (19%). The functional survival curve of the C shows the best results for the PC and the worse with the B (Log-Rank test = 6,602, p < 0.037). The main cause of failure was the catheter's extrusion (3 of the 5 failures for the B; 4 of the 6 for the CD). None of the PC was extruded. Infection and inadequate blood flow were equally found in the 3 groups. In our experience, PC give the best results because of the quality of the cuff making a good attachment in the sub-cutaneous tunnel.

  2. Placement of long-term hemodialysis catheter (permcath) in patients with end-stage renal disease through external jugular vein

    PubMed Central

    Beigi, Ali Akbar; Sharifi, Ali; Gaheri, Hafez; Abdollahi, Saeed; Esfahani, Morteza Abdar

    2014-01-01

    Background: The number of patients with End-Stage Renal Disease (ESRD) has progressively increased in the population. Kidney transplantation is the specific treatment for such patients; however a majority of patients will require hemodialysis before kidney transplantation. The present study aims to investigate using the external jugular vein (EJV) for Permcath placement in these patients. Materials and Methods: This descriptive and analytical study was conducted in Alzahra Medical Center, Isfahan, in 2012. Catheters were inserted by cutting down the right EJV. The patency rate and potential complications were studied. The obtained data was analyzed using SPSS 21.0. Results: Out of 45 live patients, within three months of surgery, 40 patients (81.6%) had no complications and dialysis continued through Permcath. Permcath Thrombosis occurred in two patients (4.4%). Catheter infection led to the removal of it in one patient (2.2%) 1.5 months after surgery. And accidental catheter removal occurred in one patient. Conclusion: Placement of the permcath in the external jugular vein can be a safe, uncomplicated, and reliable method for patients requiring hemodialysis, and can be a life-saving alternative in patients without accessible internal jugular vein. PMID:25590030

  3. Case report: central venous catheterization via internal jugular vein with associated formation of perioperative venous thrombosis during surgery in the prone position.

    PubMed

    Minami, Kimito; Mimami, Kimito; Iida, Miki; Iida, Hiroki

    2012-06-01

    An unusual case of central venous catheter (CVC)-related thrombosis during supine surgery in the prone position is presented. A 76-year-old woman was scheduled for elective surgery to repair a broken lumbar instrument. A single-lumen CVC was inserted via the right internal jugular vein. Surgery was performed in the prone position, with the patient's face directed downward in the standard median position (i.e., no rotation), but with slight forward flexion at the neck. After the surgery, the external jugular vein was dilated, and a postoperative X-ray revealed an infiltrative shadow in the right thoracic cavity. Because cervical echography showed dilated cervical veins with a "moyamoya-type" echo, possibly indicating a thrombus, contrast-enhanced computed tomography was performed, revealing a venous thrombus in the right internal jugular vein. An internal jugular venous-velocity measurement suggested that her slightly flexed neck position and her prone position during surgery may have kinked the internal jugular vein, causing engorgement with venous blood. The presence of the internal jugular venous catheter may have created thrombogenic conditions. A patient's position during surgery can reduce deep venous-flow velocity, and venous blood may stagnate, contributing greatly to thrombogenicity. We should consider a patient's position during surgery as a risk factor for thrombus formation, and a careful preoperative evaluation should be made as to which route should be chosen for CVC.

  4. Impact of misplaced subclavian vein catheter into jugular vein on transpulmonary thermodilution measurement variables*

    PubMed Central

    Yu, Wen-qiao; Zhang, Yun; Zhang, Shao-yang; Liang, Zhong-yan; Fu, Shui-qiao; Xu, Jia; Liang, Ting-bo

    2016-01-01

    Objective: The subclavian vein (SCV) is usually used to inject the indicator of cold saline for a transpulmonary thermodilution (TPTD) measurement. The SCV catheter being misplaced into the internal jugular (IJV) vein is a common occurrence. The present study explores the influence of a misplaced SCV catheter on TPTD variables. Methods: Thirteen severe acute pancreatitis (SAP) patients with malposition of the SCV catheter were enrolled in this study. TPTD variables including cardiac index (CI), global end-diastolic volume index (GEDVI), intrathoracic blood volume index (ITBVI), and extravascular lung water index (EVLWI) were obtained after injection of cold saline via the misplaced SCV catheter. Then, the misplaced SCV catheter was removed and IJV access was constructed for a further set of TPTD variables. Comparisons were made between the TPTD results measured through the IJV and misplaced SCV accesses. Results: A total of 104 measurements were made from TPTD curves after injection of cold saline via the IJV and misplaced SCV accesses. Bland-Altman analysis demonstrated an overestimation of +111.40 ml/m2 (limits of agreement: 6.13 and 216.70 ml/m2) for GEDVI and ITBVI after a misplaced SCV injection. There were no significant influences on CI and EVLWI. The biases of +0.17 L/(min·m2) for CI and +0.17 ml/kg for EVLWI were revealed by Bland-Altman analysis. Conclusions: The malposition of an SCV catheter does influence the accuracy of TPTD variables, especially GEDVI and ITBVI. The position of the SCV catheter should be confirmed by chest X-ray in order to make good use of the TPTD measurements. PMID:26739527

  5. Cardiac Variation of Internal Jugular Vein for the Evaluation of Hemodynamics.

    PubMed

    Nakamura, Kensuke; Qian, Kun; Ando, Takehiro; Inokuchi, Ryota; Doi, Kent; Kobayashi, Etsuko; Sakuma, Ichiro; Nakajima, Susumu; Yahagi, Naoki

    2016-08-01

    Evaluations of intravascular fluid volume are considered to be one of the most important assessments in emergency and intensive care. Focusing on pulse-induced variation of the internal jugular vein (IJV) area, i.e., cardiac variation, we investigated its correlation with various hemodynamic indices using newly developed software. Software that automatically can track and analyze the IJV during ultrasonography was developed. Eleven healthy patients were subjected to an exercise load to increase their stroke volume (SV) and a dehydration load to decrease their central venous pressure (CVP). The cardiac variation in the area of the IJV, CVP, the SV and the respiratory variation in the inferior vena cava (IVC) were evaluated. The exercise protocol increased the patients' mean SV by 14.5 ± 3.7 mL, and the dehydration protocol caused their mean CVP to fall by 3.75 ± 0.33 cm H2O, which resulted in the collapse index (max IJV area - min IJV area/max IJV area) changing from 0.32 ± 0.04 to 0.44 ± 0.06 and 0.49 ± 0.04, respectively (p < 0.05). The SV exhibited a strong positive correlation with the collapse index (r = 0.59, p = 0.006), and CVP showed a strong positive correlation with the body height-adjusted mean area of the IJV (r = 0.72, p < 0.001). Cardiac variation in the area of the great veins is considered to be induced by venous return to the right atrium under negative pressure. It is possible that intravascular dehydration can be detected and hemodynamic indices, such as CVP and SV, can be estimated by evaluating cardiac variation in the area of the IJV.

  6. Gamma Knife radiosurgery for glomus jugulare tumors: a single-center series of 75 cases.

    PubMed

    Ibrahim, Ramez; Ammori, Mohannad B; Yianni, John; Grainger, Alison; Rowe, Jeremy; Radatz, Matthias

    2016-07-08

    OBJECTIVE Glomus jugulare tumors are rare indolent tumors that frequently involve the lower cranial nerves (CNs). Complete resection can be difficult and associated with lower CN injury. Gamma Knife radiosurgery (GKRS) has established its role as a noninvasive alternative treatment option for these often formidable lesions. The authors aimed to review their experience at the National Centre for Stereotactic Radiosurgery, Sheffield, United Kingdom, specifically the long-term tumor control rate and complications of GKRS for these lesions. METHODS Clinical and radiological data were retrospectively reviewed for patients treated between March 1994 and December 2010. Data were available for 75 patients harboring 76 tumors. The tumors in 3 patients were treated in 2 stages. Familial and/or hereditary history was noted in 12 patients, 2 of whom had catecholamine-secreting and/or active tumors. Gamma Knife radiosurgery was the primary treatment modality in 47 patients (63%). The median age at the time of treatment was 55 years. The median tumor volume was 7 cm(3), and the median radiosurgical dose to the tumor margin was 18 Gy (range 12-25 Gy). The median duration of radiological follow-up was 51.5 months (range 12-230 months), and the median clinical follow-up was 38.5 months (range 6-223 months). RESULTS The overall tumor control rate was 93.4% with low CN morbidity. Improvement of preexisting deficits was noted in 15 patients (20%). A stationary clinical course and no progression of symptoms were noted in 48 patients (64%). Twelve patients (16%) had new symptoms or progression of their preexisting symptoms. The Kaplan-Meier actuarial tumor control rate was 92.2% at 5 years and 86.3% at 10 years. CONCLUSIONS Gamma Knife radiosurgery offers a risk-versus-benefit treatment option with very low CN morbidity and stable long-term results.

  7. Regulation of P-selectin expression by inflammatory mediators in canine jugular endothelial cells.

    PubMed

    Doré, M; Sirois, J

    1996-11-01

    Canine endothelial cells express the adhesion molecule P-selectin to mediate the initial attachment of leukocytes to the vessel wall. Although it is known that agents like histamine and thrombin stimulate the surface expression of P-selectin, the effect of inflammatory mediators and cytokines such as lipopolysaccharides (LPS), tumor necrosis factor-alpha (TNF-alpha), and interleukin-1 beta (IL-1 beta) on canine P-selectin expression has not been investigated. Therefore, the objective of this study was to analyze the regulation of P-selectin messenger RNA (mRNA) and protein by these cytokines in canine endothelial cells isolated from jugular veins. Analyses of cytoplasmic RNA by Northern blotting showed that stimulation of culture endothelial cells with either LPS (100 ng/ml) or recombinant human TNF-alpha (30 U/ml) for 3 or 6 hours significantly increased (P < 0.05) steady-state levels of mRNA for P-selectin (3.8- +/- 1.0- and 3.0- +/- 0.4-fold increase for LPS at 3 and 6 hours, respectively, and 2.5- +/- 0.8- and 2.7- +/- 0.9-fold increase for TNF-alpha at 3 and 6 hours, respectively). P-selectin mRNA had decreased by 48 hours to levels found in unstimulated cells. In contrast, human IL-1 beta had no effect on P-selectin mRNA. Increased levels of mRNA with LPS stimulation were associated with the synthesis of new protein, as demonstrated by the positive staining in LPS-stimulated cells using immunocytochemistry with a monoclonal antibody against canine P-selectin (MD3). These results reveal that important inflammatory mediators and cytokines such as LPS and TNF-alpha induce the synthesis of new P-selectin and suggest that this process could represent a means of sustaining local leukocyte recruitment for several hours during an acute inflammatory reaction.

  8. Internal Jugular Vein Cross-Sectional Area Enlargement Is Associated with Aging in Healthy Individuals

    PubMed Central

    Magnano, Christopher; Belov, Pavel; Krawiecki, Jacqueline; Hagemeier, Jesper; Beggs, Clive; Zivadinov, Robert

    2016-01-01

    Background Internal jugular vein (IJV) narrowing has been implicated in central nervous system pathologies, however normal physiological age- and gender-related IJV variance in healthy individuals (HIs) has not been adequately assessed. Objectives We assessed the relationship between IJV cross-sectional area (CSA) and aging. Materials and Methods This study involved 193 HIs (63 males and 130 females) who received 2-dimensional magnetic resonance venography at 3T. The minimum CSA of the IJVs at cervical levels C2/C3, C4, C5/C6, and C7/T1 was obtained using a semi-automated contouring-thresholding technique. Subjects were grouped by decade. Pearson and partial correlation (controlled for cardiovascular risk factors, including hypertension, heart disease, smoking and body mass index) and analysis of variance analyses were used, with paired t-tests comparing side differences. Results Mean right IJV CSA ranges were: in males, 41.6 mm2 (C2/C3) to 82.0 mm2 (C7/T1); in females, 38.0 mm2 (C2/C3) to 62.3 mm2 (C7/T1), while the equivalent left side ranges were: in males, 28.0 mm2 (C2/C3) to 52.2 mm2 (C7/T1); in females, 27.2 mm2 (C2/C3) to 47.8 mm2 (C7/T1). The CSA of the right IJVs was significantly larger (p<0.001) than the left at all cervical levels. Controlling for cardiovascular risk factors, the correlation between age and IJV CSA was more robust in males than in the females for all cervical levels. Conclusions In HIs age, gender, hand side and cervical location all affect IJV CSA. These findings suggest that any definition of IJV stenosis needs to account for these factors. PMID:26895434

  9. Delphi Method Validation of a Procedural Performance Checklist for Insertion of an Ultrasound-Guided Internal Jugular Central Line.

    PubMed

    Hartman, Nicholas; Wittler, Mary; Askew, Kim; Manthey, David

    2016-01-01

    Placement of ultrasound-guided central lines is a critical skill for physicians in several specialties. Improving the quality of care delivered surrounding this procedure demands rigorous measurement of competency, and validated tools to assess performance are essential. Using the iterative, modified Delphi technique and experts in multiple disciplines across the United States, the study team created a 30-item checklist designed to assess competency in the placement of ultrasound-guided internal jugular central lines. Cronbach α was .94, indicating an excellent degree of internal consistency. Further validation of this checklist will require its implementation in simulated and clinical environments.

  10. We still go for the jugular: implications of the 3SITES central venous catheter study for nephrology.

    PubMed

    Wyatt, Christina M; Vassalotti, Joseph A

    2016-03-01

    The 3SITES study randomly assigned a nontunneled central venous catheter site in over 3000 adults treated in intensive care units. The subclavian site was associated with a lower rate of short-term complications, including catheter-related bloodstream infection and deep venous thrombosis, compared to the femoral or internal jugular site. Nephrologists should be aware of this study and should continue to advocate for alternatives to subclavian vein catheter placement in patients with chronic kidney disease who are expected to require arteriovenous access for dialysis in the future.

  11. Videothoracoscopic management of a perforated central vein and pleura after ultrasound-guided internal jugular vein cannulation: a case report

    PubMed Central

    Kim, Jeong-Eun; Jeon, Joon-Pyo; Kim, Yongsuk; Jeong, Su Ah

    2014-01-01

    A 23-year-old male underwent a left internal jugular vein catheterization during extended surgery for treatment of multiple fractures due to a traffic accident. Although the catheterization was performed under ultrasound (US) guidance, iatrogenic perforation of the central vein and pleura occurred. The catheter was removed, and the perforated site was addressed under thoracoscopy rather than an open thoracotomy. This case suggests that using US does not completely guarantee a complication-free outcome, and that catheter placement should be carefully confirmed. In addition, this case suggests that thoracoscopy may be an ideal method of resolving a perforation of the central vein and pleura. PMID:24851167

  12. Bilateral surgical reconstruction for internal jugular veins disease in patients with chronic cerebrospinal venous insufficiency and associated multiple sclerosis.

    PubMed

    Spagnolo, Salvatore; Scalise, Filippo; Barbato, Luciano; Grasso, Maria Antonietta; Tesler, Ugo F

    2014-10-01

    Chronic cerebrospinal venous insufficiency (CCSVI) is a vascular condition characterized by morphologic alterations involving efferent cerebral vascular paths. CCSVI has been implicated as a contributing factor to multiple sclerosis (MS) but this theory is highly controversial. We report 3 cases of CCSVI patients with MS who had undergone internal jugular veins (IJVs) angioplasty to restore vessels patency. All patients reported significant symptomatic improvement after angioplasty until symptoms recurred after restenosis of the treated IJVs. Surgical IJVs reconstruction was performed. Patients' symptoms gradually improved and the benefits were maintained at the 1-year follow-up.

  13. Gamma Knife surgery for patients with jugular foramen schwannomas: a multiinstitutional retrospective study in Japan.

    PubMed

    Hasegawa, Toshinori; Kato, Takenori; Kida, Yoshihisa; Sasaki, Ayaka; Iwai, Yoshiyasu; Kondoh, Takeshi; Tsugawa, Takahiko; Sato, Manabu; Sato, Mitsuya; Nagano, Osamu; Nakaya, Kotaro; Nakazaki, Kiyoshi; Kano, Tadashige; Hasui, Koichi; Nagatomo, Yasushi; Yasuda, Soichiro; Moriki, Akihito; Serizawa, Toru; Osano, Seiki; Inoue, Akira

    2016-10-01

    OBJECTIVE This study aimed to explore the efficacy and safety of stereotactic radiosurgery in patients with jugular foramen schwannomas (JFSs). METHODS This study was a multiinstitutional retrospective analysis of 117 patients with JFSs who were treated with Gamma Knife surgery (GKS) at 18 medical centers of the Japan Leksell Gamma Knife Society. The median age of the patients was 53 years. Fifty-six patients underwent GKS as their initial treatment, while 61 patients had previously undergone resection. At the time of GKS, 46 patients (39%) had hoarseness, 45 (38%) had hearing disturbances, and 43 (36%) had swallowing disturbances. Eighty-five tumors (73%) were solid, and 32 (27%) had cystic components. The median tumor volume was 4.9 cm(3), and the median prescription dose administered to the tumor margin was 12 Gy. Five patients were treated with fractionated GKS and maximum and marginal doses of 42 and 21 Gy, respectively, using a 3-fraction schedule. RESULTS The median follow-up period was 52 months. The last follow-up images showed partial remission in 62 patients (53%), stable tumors in 42 patients (36%), and tumor progression in 13 patients (11%). The actuarial 3- and 5-year progression-free survival (PFS) rates were 91% and 89%, respectively. The multivariate analysis showed that pre-GKS brainstem edema and dumbbell-shaped tumors significantly affected PFS. During the follow-up period, 20 patients (17%) developed some degree of symptomatic deterioration. This condition was transient in 12 (10%) of these patients and persistent in 8 patients (7%). The cause of the persistent deterioration was tumor progression in 4 patients (3%) and adverse radiation effects in 4 patients (3%), including 2 patients with hearing deterioration, 1 patient with swallowing disturbance, and 1 patient with hearing deterioration and hypoglossal nerve palsy. However, the preexisting hoarseness and swallowing disturbances improved in 66% and 63% of the patients, respectively

  14. Jugular venous `a' wave in pulmonary hypertension: new insights from a Doppler echocardiographic study

    PubMed Central

    Stojnic, Bojan B; Brecker, Stephen J D; Xiao, Han B; Gibson, Derek G

    1992-01-01

    Objective—To study the mechanisms underlying the dominant `a' wave seen in patients with primary pulmonary hypertension. Design—Retrospective and prospective examination of the jugular venous pulse recording, flow in the superior vena cava, and Doppler echocardiographic studies. Setting—A tertiary referral centre for both cardiac and pulmonary disease, with facilities for invasive and noninvasive investigation, and assessment for heart and heart-lung transplantation. Patients—12 patients with primary pulmonary hypertension, most being considered for heart-lung transplantation. Results—Two distinct patterns of venous pulse and superior vena caval flow were identified: a dominant `a' wave with no `v' wave, an absent or poorly developed `y' descent, and exclusively systolic downward flow in the superior vena cava (group 1, n = 8), and a dominant `v' wave, deep `y' descent and exclusively diastolic downward flow in the superior vena cava (group 2, n = 4). A comparison between the two groups showed age (mean (SD)) 42 (18) ν 36 (7) years, RR interval 700 (65) ν 740 (240) ms, left ventricular end diastolic dimension 3·6 (0·8) ν 3·2 (1·0) cm and end systolic dimension 2·1 (0·5) ν 2·3 (0·3) cm, right ventricular end diastolic dimension 2·6 (0·5) ν 2·8 (0·6) cm, and pressure drop between right ventricle and right atrium 60 (8) ν 70 (34) mm Hg to be similar. Duration of tricuspid regurgitation 520 (30) ν 420 (130) ms and the time interval of pulmonary closure to the end of the tricuspid regurgitant signal 140 (30) ν 110 (40) ms were longer in group 1 compared with group 2, whereas right ventricular filling time was much shorter 180 (70) ν 350 (130) ms. In seven patients from group 1, a single peak of forward tricuspid flow was present, but this pattern was seen in only one patient from group 2. Conclusions—In patients with primary pulmonary hypertension, the apparent `a' wave seen in the venous pulse is, in fact, a summation wave. It is

  15. Effective use of flow-spoiled FBI and time-SLIP methods in the diagnostic study of an aberrant vessel of the head and neck: "left jugular venous steal by the right jugular vein".

    PubMed

    Kogure, Taroh; Kogure, Kyuya; Iizuka, Mitsumasa; Ino, Azusa; Ishii, Masako

    2010-08-01

    Three-dimensional (3D) time-of-flight (TOF) is now commonly used in routine magnetic resonance angiography (MRA) studies of the head and neck. However, there are limits to its diagnostic abilities in the clinical field and, in some instances, a more invasive supplementary examination may be required. We incidentally discovered a patient with an aberrant vessel of the head and neck that ran alongside the left carotid artery and contained a constant, slowly pulsating efferent blood flow. 3D-TOF and carotid ultrasonography could not determine the nature and origin of this vessel. Additional studies using flow-spoiled fresh blood imaging (flow-spoiled FBI) and time spatial labeling inversion pulse (time-SLIP) methods were effective in determining that the vessel was the left jugular vein, and that the continuous venous reflux was a result of a venous steal by the right jugular vein. We show that by combining different MRA techniques we can effectively achieve diagnosis without resorting to more invasive examinations.

  16. Extraordinary cerebral venous drainage pathway with mastoid emissary and posterior external jugular veins detected by contrast-enhanced neck computed tomography.

    PubMed

    Bulbul, Erdogan; Yanik, Bahar; Demirpolat, Gulen; Koksal, Vildan

    2015-12-01

    An extraordinary cerebral venous drainage pathway and dilated vein at the left posterior cervical region were detected with routine contrast-enhanced neck computed tomography exam. The left sigmoid sinus was drained by dilated mastoid emissary vein (MEV). The MEV continued as posterior auricular and posterior external jugular veins (PEJVs). The left PEJV directly drained into subclavian vein. Atretic right transverse sinus, left facial vein forming the external jugular vein, atresia and hypoplasia of upper internal jugular veins at the right and left sides, respectively, were the other uncommon findings in our case. Detecting venous variations may prevent complications during surgical and interventional procedures, so the radiologists should examine the superficial cervical veins closely.

  17. JUGULAR CENTRAL VENOUS CATHETER PLACEMENT THROUGH A MODIFIED SELDINGER TECHNIQUE FOR LONG-TERM VENOUS ACCESS IN CHELONIANS.

    PubMed

    Pardo, Mariana A; Divers, Stephen

    2016-03-01

    Long-term or repeated venous access in chelonians is difficult to obtain and manage, but can be critically important for administration of medications and blood sampling in hospitalized patients. Jugular catheterization provides the most rapid and secure route for vascular access, but catheters can be difficult to place, and maintaining catheter patency may be challenging. Long multilumen polyurethane catheters provide flexibility and sampling access, and minimize difficulties, such as catheter displacement, that have been encountered with traditional over-the-needle catheters. We describe placement of 4 Fr. 13-cm polyurethane catheters in three chelonians with the use of a modified Seldinger technique. Venous access was obtained with the use of an over-the-needle catheter, which allowed placement of a 0.018-in.-diameter wire, over which the polyurethane catheter was placed. Indwelling time has ranged between 1 and 4 mo currently. All tortoises were sedated for this procedure. Polyurethane central catheters provide safe, long-term venous access that allows clinicians to perform serial blood sampling as well as intravenous administration of medications, anesthetic agents, and fluids. A jugular catheter can also allow central venous pressure measurement. Utilization of central line catheters was associated with improvements in diagnostic efficiency and therapeutic case management, with minimal risks and complications.

  18. Effect of the thigh-cuffs on the carotid artery diameter jugular vein section and facial skin edema: HDT study.

    NASA Astrophysics Data System (ADS)

    Roumy, Jerome; Diridillou, Stephane; Herault, Stephane; Fomina, Galina; Alferova, Irina; Arbeille, Philippe

    2001-08-01

    Objective: To evaluate the distal arterial, venous and skin changes in a group using thigh cuffs during daytime and in a control group. Method: Cardiac, arterial, venous parameters were measured by echography and Doppler. Skin thickness was measured by high frequency echography. Results & discussion: Head down position induced plasma volume reduction, increased cerebral resistance, reduced lower limb resistance. The jugular vein increased whereas the femoral and popliteal veins decreased. All these changes were already observed in previous HDT. Common carotid diameter decreased, Front head skin thickness increased and Tibial skin thickness decreased. Eight hours with thigh cuffs increased the cardiac and carotid sizes which is in agreement with the plasma volume increase. Conversely they reduced the cerebral vascular resistance, jugular section and front head edema which may explain the sensation of comfort reported by the subjects. At the lower limb level the thigh cuffs restored the skin thickness to pre-HDT level but enlarged markedly the femoral and popliteal veins. HR, BP, CO, TPR did not change.

  19. Post-coital intra-cerebral venous hemorrhage in a 78-year-old man with jugular valve incompetence: a case report

    PubMed Central

    2010-01-01

    Introduction Spontaneous intra-cerebral hemorrhage can occur in patients with venous disease due to obstructed venous outflow. Case presentation We report the case of a 78-year-old Caucasian man with jugular valve incompetence who experienced an intra-cerebral temporo-occipital hemorrhage following sexual intercourse. He had no other risk factors for an intra-cerebral hemorrhage. Conclusions To the best of our knowledge, this is the first case of intra-cerebral hemorrhage due to jugular valve incompetence in association with the physical exertion associated with sexual intercourse. PMID:20659320

  20. Internal jugular vein thrombosis presenting as a painful neck mass due to a spontaneous dislocated subclavian port catheter as long-term complication: a case report

    PubMed Central

    Grommes, Jochen; Junge, Karsten; Göbner, Sonja; Schumpelick, Volker; Truong, Son

    2009-01-01

    Central venous access devices are extensively used for long-term chemotherapy and parenteral nutrition. However, there are some possible immediate, early, and late complications related to the implantation technique, care, and maintenance. We present the uncommon occurrence of a thrombosis of the internal jugular vein due to a spontaneous migration of a Port-A-Cath catheter into the ipsilateral internal jugular vein as a delayed complication of a central venous access catheter implanted for chemotherapy delivery. A review of the literature is given, and the factors responsible for this unusual complication will be discussed. PMID:19830037

  1. A Case Study of Deep Vein Thrombosis of the Right Internal Jugular Vein in a Healthy 21-Year-Old Male

    PubMed Central

    Villanueva, Geri

    2016-01-01

    We are reporting a case of a healthy 21-year-old male, with no significant past medical history, who was found to have an incidental nonocclusive deep vein thrombosis in the right internal jugular vein detected on a head MRI previously ordered for work-up of headaches. A follow-up upper extremity venous Doppler ultrasound confirmed the presence of a partially occlusive deep vein thrombosis in the right jugular vein. The case presented is unique for the reason that the patient is young and has no prior risk factor, personal or familial, for venous thrombosis except for associated polycythemia on clinical presentation. PMID:27725891

  2. Central venous catheterization--an anatomical review of a clinical skill. Part 2. Internal jugular vein via the supraclavicular approach.

    PubMed

    Boon, J M; van Schoor, A N; Abrahams, P H; Meiring, J H; Welch, T

    2008-01-01

    The safe and successful performance of a central venous catheterization (CVC) requires a specific knowledge of anatomy in addition to a working knowledge. Misunderstanding the anatomy may result in failure or complications. This review aims to aid understanding of the anatomical framework, pitfalls, and complications of CVC of the internal jugular veins. CVC is common practice amongst surgeons, anesthesiologists, and emergency room physicians during the preparations for major surgical procedures such as open-heart surgery, as well as for intensive care monitoring and rapid restoration of blood volume. Associated with this technique are certain anatomical pitfalls and complications that can be successfully avoided if one possesses a thorough knowledge of the contraindications, regional anatomy, and rationale of the technique.

  3. The formation of the superior and jugular ganglia: insights into the generation of sensory neurons by the neural crest.

    PubMed

    Thompson, Hannah; Blentic, Aida; Watson, Sheona; Begbie, Jo; Graham, Anthony

    2010-02-01

    The superior and jugular ganglia (S/JG) are the proximal ganglia of the IXth and Xth cranial nerves and the sensory neurons of these ganglia are neural crest derived. However, it has been unclear the extent to which their differentiation resembles that of the Dorsal Root Ganglia (DRGs). In the DRGs, neural crest cells undergo neuronal differentiation just after the onset of migration and there is evidence suggesting that these cells are pre-specified towards a sensory fate. We have analysed sensory neuronal differentiation in the S/JG. We show, in keeping with previous studies, that neuronal differentiation initiates long after the cessation of neural crest migration. We also find no evidence for the existence of migratory neural crest cells pre-specified towards a sensory phenotype prior to ganglion formation. Rather our results suggest that sensory neuronal differentiation in the S/JG is the result of localised spatiotemporal cues.

  4. Venous anastomosis in free flap reconstruction after radical neck dissection: is the external jugular vein a feasible option?

    PubMed

    Reiter, Maximilian; Baumeister, Philipp

    2017-01-13

    Free microvascular tissue transfer has become a reliable and wellestablished technique in reconstructive surgery. Success rates greater than 95% are constantly reported in the literature. End-to-end anastomosis to the external jugular vein (EJ) is supposed to be equally successful as anastomosis to the internal jugular vein (IJ) in patients treated with selective neck dissection. No data has been published so far when the IJ had to be resected during neck dissection. The purpose of this study was to evaluate the success rate and complications of end-to-end anastomosis to the EJ in cases of (modified) radical neck dissection with resected IJ. A retrospective mono-center cohort study was performed. All patients with end-to-end anastomosis to either the IJ or EJ-system were reviewed. 423 free-tissue transfers performed between 2009 and 2016 were included. The overall success rate was 97.0% with an anastomotic revision rate due to venous thrombosis of 12.3%. In patients when the IJ had to be resected and the venous anastomosis was performed at the ipsilateral side to the EJ (n = 53), overall flap loss was significantly higher (5/53; 9.4%). The revision rate in these cases was 22.6%. Success rate of anastomosis to the EJ when the ipsilateral IJ was still intact was 100% (n = 20). Success rate when the anastomosis was performed at the contralateral side was 100%. End-to-end anastomosis to the EJ in cases with resected IJ is more likely to result in free flap loss. Furthermore, it is associated with a higher revision rate. Therefore, in cases with resected IJ, we suggest to plan the operation beforehand with anastomosis at the contralateral side whenever possible.

  5. A neurofibroma affecting the first right cervical sympathetic ganglion and entering the jugular foramen of the skull base.

    PubMed

    Kumchev, Y; Kalnev, B

    1997-01-01

    The case of a 27 year old male patient is presented. He had been complaining for three months prior to his initial medical examination of severe pulsating headache in the right occipital region, propagating toward the right parietal and temporal regions, occasionally extending along the neck to the right shoulder. The pain subsequently spread over the right tonsil, the voice became hoarse and the patient experienced difficulties in swallowing. On admission to our Department we found: persistent attacks of headache, dysphonia, dysphagia, the palatine arch was slow during phonation. The right pharyngeal reflex was absent, there was pain on palpation over the right occipital bone and the antero-lateral region of the neck, as well as hypotrophy of the right sternocleidomastoid muscle. Selective right carotid arteriogram was performed--the A/P view revealed lateral displacement of the right internal carotid artery 3 cm above the bifurcation, while on lateral view the artery was pushed forward. Computed tomography of the neck with bolus contrast enhancement showed a space-occupying lesion which caused asymmetry of right pharyngeal valleculae. During surgery the tumor was found to have a spindleform shape, to emerge from the jugular foramen and to involve within its capsule the first cervical sympathetic ganglion. After enlarging the jugular foramen we achieved total extirpation of the tumor along with the first right sympathetic ganglion. The histological characteristics of the specimen defined it as neurofibroma and neural ganglion. The headache subsided in the postoperative period, recovery of the voice without dysphonia was also noted. A month later the fibrillar contractions of the tongue disappeared.

  6. [A case of a flapping infected thrombus in the internal jugular vein, septic pneumonias and heparin-induced thrombocytopaenia].

    PubMed

    Majdák, P; Kubík, J; Harmátová, L

    2011-01-01

    We present a case of a 54 years old female patient after anterior wall left ventricular myocardial infarction in 2005 who underwent coronary artery bypass graft (CABG) surgery requiring cannulation of the right internal jugular vein (IJV). She was admitted to a Department of Pulmonary Diseases with left bronchopneumonia (BPN) following 7 day treatment, with hemoptysis, dyspnoea and fevers. Duplex ultrasound (DUS) was used to diagnose flapping thrombus in the right IJV, severe thrombocytopenia and, in addition, progressing multiple infiltrates on X-ray a few days later. We empirically adjusted the treatment initiated in primary care and observed deterioration of the severe thrombocytopenia during treatment with low molecular weight heparine. We diagnosed heparin-induced thrombocytopenia (HIT) and, even though this indication was not included in our drug formulary, we initiated treatment with Arixtra (fondaparinux) 2.5 mg s.c. daily. Intensive conservative treatment was associated with significant clinical and laboratory improvement of the condition, significant regression of the IJV thrombus as well as the finding on X-ray. The final effective antibiotic treatment lasted 20 (amoxicillin + clavulanate) and 10 (clindamycin) days, respectively. Treatment with Arixtra (fondaparinux) continued in primary care and lasted a total of 65 days until normal thrombocyte levels were achieved, with gradual transition to oral anticoagulation treatment. The patient was discharged to primary care on the 23rd day of hospitalization when she was stabilized, a febrile and her cardiopulmonary functions were compensated. We did not identify any case of treatment of jugular thrombosis and concurrent HIT with fondaparin anywhere in the international literature.

  7. Isolation of endothelial colony-forming cells from blood samples collected from the jugular and cephalic veins of healthy adult horses.

    PubMed

    Sharpe, Ashley N; Seeto, Wen J; Winter, Randolph L; Zhong, Qiao; Lipke, Elizabeth A; Wooldridge, Anne A

    2016-10-01

    OBJECTIVE To evaluate optimal isolation of endothelial colony-forming cells (ECFCs) from peripheral blood of horses. SAMPLE Jugular and cephalic venous blood samples from 17 adult horses. PROCEDURES Each blood sample was divided; isolation was performed with whole blood adherence (WBA) and density gradient centrifugation (DGC). Isolated cells were characterized by uptake of 1,1'-dioctadecyl-3,3,3',3'-tetramethylindocarbocyanine perchlorate-labeled acetylated low-density lipoprotein (DiI-Ac-LDL), vascular tubule formation, and expression of endothelial (CD34, CD105, vascular endothelial growth factor receptor-2, and von Willebrand factor) and hematopoietic (CD14) cell markers by use of indirect immunofluorescence assay (IFA) and flow cytometry. RESULTS Colonies with cobblestone morphology were isolated from 15 of 17 horses. Blood collected from the cephalic vein yielded colonies significantly more often (14/17 horses) than did blood collected from the jugular vein (8/17 horses). Of 14 cephalic blood samples with colonies, 13 were obtained with DGC and 8 with WBA. Of 8 jugular blood samples with colonies, 8 were obtained with DGC and 4 with WBA. Colony frequency (colonies per milliliter of blood) was significantly higher for cephalic blood samples and samples isolated with DGC. Cells formed vascular tubules, had uptake of DiI-Ac-LDL, and expressed endothelial markers by use of IFA and flow cytometry, which confirmed their identity as ECFCs. CONCLUSIONS AND CLINICAL RELEVANCE Maximum yield of ECFCs was obtained for blood samples collected from both the jugular and cephalic veins and use of DGC to isolate cells. Consistent yield of ECFCs from peripheral blood of horses will enable studies to evaluate diagnostic and therapeutic uses.

  8. Surgical outcomes of lateral approach for jugular foramen schwannoma: postoperative facial nerve and lower cranial nerve functions.

    PubMed

    Cho, Yang-Sun; So, Yoon Kyoung; Park, Kwan; Baek, Chung-Hwan; Jeong, Han-Sin; Hong, Sung Hwa; Chung, Won-Ho

    2009-01-01

    The lateral surgical approach to jugular foramen schwannomas (JFS) may result in complications such as temporary facial nerve palsy (FNP) and hearing loss due to the complicated anatomical location. Ten patients with JFS surgically treated by variable methods of lateral approach were retrospectively reviewed with emphasis on surgical methods, postoperative FNP, and lower cranial nerve status. Gross total removal of the tumors was achieved in eight patients. Facial nerves were rerouted at the first genu (1G) in six patients and at the second genu in four patients. FNP of House-Brackmann (HB) grade III or worse developed immediately postoperatively in six patients regardless of the extent of rerouting. The FNP of HB grade III persisted for more than a year in one patient managed with rerouting at 1G. Among the lower cranial nerves, the vagus nerve was most frequently paralyzed preoperatively and lower cranial nerve palsies were newly developed in two patients. The methods of the surgical approach to JFS can be modified depending on the size and location of tumors to reduce injury of the facial nerve and loss of hearing. Careful manipulation and caution are also required for short facial nerve rerouting as well as for long rerouting to avoid immediately postoperative FNP.

  9. Using Ultrasound-Guided Peripheral Catheterization of the Internal Jugular Vein in Patients With Difficult Peripheral Access.

    PubMed

    Butterfield, Michael; Abdelghani, Ramsy; Mohamad, Maha; Limsuwat, Chok; Kheir, Fayez

    2015-10-08

    Vascular access is necessary in patients admitted to the intensive care unit and the medical ward. Currently, there are multiple modalities to achieve adequate vascular access, each with their own difficulties and drawbacks. Often, in patients with certain comorbidities, it is difficult to obtain a peripheral intravenous (IV) line, which can lead to multiple failed attempts in achieving access. We describe the feasibility of inserting an ultrasound (US)-guided peripheral IV catheter into the internal jugular vein (IJ) in such populations. This was a prospective observational case series in patients with difficult or failed peripheral IV access. All patients underwent sterile insertion of a peripheral IV catheter (2.5″, 18 gauge) into the IJ under US guidance. Catheter placement was confirmed by ultrasonography. Nineteen consecutive patients were included in this series. A total of 20 US-guided peripheral IJ catheters were placed. The mean patient age was 57. Sixty percent of patients were male and the mean body mass index was 26 (14.1-51.5). The mean time taken to place the peripheral IJ catheter was 5.3 minutes. Eighty-five percent of catheters placed were mostly placed in the right IJ. There were no complications on follow-up. US-guided placement of peripheral IV catheters in the IJ is feasible to achieve short-term IV access in a select patient population who failed traditional peripheral IV placement. Furthermore, larger trials are needed to confirm safety and long-term complications of this method.

  10. [Continuous monitoring of oxygen saturation in the jugular vein bulb in severe head injuries. Management and case reviews].

    PubMed

    Larráyoz Iriarte, J M; Mariñelarena Huárriz, A C; Martínez de Losa Carvajal, S

    1999-01-01

    Since october 1996, the Intensive Care Unit of the Hospital of Navarra has carried out continuous monitoring of oxygen saturation in the bulb of the internal jugular vein (SjO2). This technique, used in patients with severe cranioencephalic trauma (SCET), is designed to facilitate care an ensure the use of adequate therapeutic measures in such patients. The present study has two parts: In the first part, SjO2 monitoring is defined and catheter insertion techniques, technical problems, and nursing care are described. In the second part, a retrospective review is made of patients admitted to the unit from october 1996 to october 1997 who underwent SjO2 monitoring. A total of 11 cases are included, the common features of which were: SCET, intracranial pressure over 20 mmHg, Glasgow score of 8 or less, and abnormal CAT study. This study provides a basis for developing a nursing protocol because familiarity with the technique allows problems to be prevented and/or resolved.

  11. Relationship between intracranial hypertension and ultrasonic patterns of the common carotid artery and the internal jugular vein.

    PubMed

    Liboni, W; Bertolotto, A; Urciuoli, R

    1983-01-01

    The Doppler technique has only been used in neurological practice to evidence local vessel pathology such as occlusion or stenosis. Both common carotid artery and internal jugular vein flows can change not only because of pathological processes of the vessels but also because of impedance of their distribution territory. In this report we analyze the relationship between flow velocity, one of the parameters of blood flow, and intracranial impedance variations which occur in cerebral concussion, tumors and acute vascular cerebral pathology. During our observations we noticed that the diastolic wave of the velocity curve of the common carotid artery is a very important signal of the flow variations in the internal carotid artery and, in turn, of variations in cerebral flow. We studied the behaviour of the common carotid artery velocity curve in our patients both during clinical disease development and during the action of mannitol in the acute phases of the disease. We found that the ultrasonic patterns during antiedema action were similar to the ones obtained during the recovery period. We were able to note some differences and some similarities of the curve morphology in relation to generalized or focal causes of cerebral edema. This may be very important considering that at present no non-invasive and therefore repeatable technique is available for monitoring cerebral blood flow in intracranial hypertension.

  12. Ipsilateral jugular to distal subclavian vein transposition to relieve central venous hypertension in rescue vascular access surgery: a surgical report of 3 cases.

    PubMed

    Acri, Ignazioe; Carmignani, Amedeo; Vazzana, Giovanni; Massara, Mafalda; Acri, Edvige; Lentini, Salvatore; Spinelli, Francesco

    2013-01-01

    Central venous thrombosis may often arise following central venous cannulation for temporary haemodialysis access. Venous thrombosis may be clinically asymptomatic due to the presence of collateral circulation. However, if an arteriovenous (AV) fistula is prepared below the obstructed venous segment, then symptoms may occur. Central venous hypertension interferes with dialysis, compromises limb function and threatens its safety. Percutaneous treatment is mostly used. However, in some cases endovascular treatment may not be as easy and long term patency uncertain.We report our experience on 3 patients on chronic hemodialysis treatment presenting with a patent AV fistula and ipsilateral subclavian vein chronic fibrotic obstruction. They were treated by ipsilateral internal jugular to distal subclavian vein transposition. Two separate surgical incisions were performed to expose the subclavian vein distally to the occlusion and the jugular vein that was distally ligated and transposed. There was no mortality nor significant postoperative complications. Resolution of hypertensive symptoms was achieved within 3-4 weeks in all patients. The AV fistula was used for dialysis treatment starting from the first postoperative day. At follow-up (mean 13 months), there was no recurrence of upper limb venous hypertension.In patients with subclavian occlusion and ipsilateral low flow, patent AV fistula, jugular to distal subclavian vein transposition may prove useful in cases when percutaneous angioplasty is technically not feasible or long term patency is not expected.

  13. Hemodynamics and right-ventricle functional characteristics of a swine carotid artery-jugular vein shunt model of pulmonary arterial hypertension: An 18-month experimental study

    PubMed Central

    Luo, Xiaoju; Huang, Yuanyuan; He, Yun; Li, Zhixian

    2015-01-01

    The continuous changes in pulmonary hemodynamic properties and right ventricular (RV) function in pulmonary arterial hypertension (PAH) have not been fully characterized in large animal model of PAH induced by a carotid artery–jugular vein shunt. A minipig model of PAH was induced by a surgical anastomosis between the left common carotid artery and the left jugular vein. The model was validated by catheter examination and pathologic analyses, and the hemodynamic features and right-ventricle functional characteristics of the model were continuously observed by Doppler echocardiography. Of the 45 minipigs who received the surgery, 27 survived and were validated as models of PAH, reflected by mean pulmonary artery pressure ≥25 mmHg, and typical pathologic changes of pulmonary arterial remodeling and RV fibrosis. Non-invasive indices of pulmonary hemodynamics (pulmonary artery accelerating time and its ratio to RV ventricular ejection time) were temporarily increased, then reduced later, similar to changes in tricuspid annular displacement. The Tei index of the RV was elevated, indicating a progressive impairment in RV function. Surgical anastomosis between carotid artery and jugular vein in a minipig is effective to establish PAH, and non-invasive hemodynamic and right-ventricle functional indices measured by Doppler echocardiography may be used as early indicators of PAH. PMID:25595189

  14. A comparative study of magnetic resonance venography techniques for the evaluation of the internal jugular veins in multiple sclerosis patients☆

    PubMed Central

    Rahman, M. Tamizur; Sethi, Sean K.; Utriainen, David T.; Hewett, J. Joseph; Haacke, E. Mark

    2014-01-01

    Background and Purpose The use of magnetic resonance imaging (MRI) to assess the vascular nature of diseases such as multiple sclerosis (MS) is a growing field of research. This work reports on the application of MR angiographic (MRA) and venographic (MRV) techniques in assessing the extracranial vasculature in MS patients. Materials and Methods A standardized MRI protocol containing 2D TOF-MRV and dynamic 3D contrast-enhanced (CE) MRAV was run for 170 MS patients and 40 healthy controls (HC). The cross-sectional area (CSA) of the internal jugular veins (IJVs) was measured at three neck levels in all subjects for both MRV techniques to determine the presence of venous stenoses. All data were analyzed retrospectively. Results For the values where both methods showed signal, the 3D method showed larger CSA measurement values compared to 2D methods in both IJVs, in both MS and HC subjects which was confirmed with student paired t-tests. Of the 170 MS patients, 93 (55%) in CE-MRAV and 103 (61%) in TOF-MRV showed stenosis in at least one IJV. The corresponding numbers for the 40 HC subjects were 2 (5%) and 4 (10%), respectively. Carotid ectasias with IJV stenosis were seen in 26 cases (15%) with 3D CE-MRAV and were not observable with 2D TOF-MRV. Carotid ectasias were not seen in the HC group. In the 2D TOF-MRV data, banding of the IJVs related to slow flow was seen in 58 (34%) MS cases and in no HC cases. MS patients showed lower average CSAs than the HC subjects. Conclusion The 3D CE MRAV depicted the vascular anatomy more completely than the 2D TOF-MRV. However, the 3D CE MRAV does not provide any information about the flow characteristics which are indirectly available in the 2D TOF-MRV in those cases where there is slow flow. PMID:23850076

  15. The effects of the Trendelenburg position and the Valsalva manoeuvre on internal jugular vein diameter and placement in children

    PubMed Central

    Dincyurek, Gamze Naime; Mogol, Elif Basagan; Turker, Gurkan; Yavascaoglu, Belgin; Gurbet, Alp; Kaya, Fatma Nur; Moustafa, Bachri Ramadan; Yazici, Tolga

    2015-01-01

    INTRODUCTION We compared the effects of various surgical positions, with and without the Valsalva manoeuvre, on the diameter of the right internal jugular vein (RIJV). METHODS We recruited 100 American Society of Anesthesiologists physical status class I patients aged 2–12 years. The patients’ heart rate, blood pressure, peripheral oxygen saturation and end-tidal CO2 pressure were monitored. Induction of anaesthesia was done using 1% propofol 10 mg/mL and fentanyl 2 µg/kg, while maintenance was achieved with 2% sevoflurane in a mixture of 50/50 oxygen and air (administered via a laryngeal mask airway). The RIJV diameter was measured using ultrasonography when the patient was in the supine position. Thereafter, it was measured when the patient was in the supine position + Valsalva, followed by the Trendelenburg, Trendelenburg + Valsalva, reverse Trendelenburg, and reverse Trendelenburg + Valsalva positions. A 15° depression or elevation was applied for the Trendelenburg position, and an airway pressure of 20 cmH2O was applied in the Valsalva manoeuvre. During ultrasonography, the patient’s head was tilted 20° to the left. RESULTS When compared to the mean RIJV diameter in the supine position, the mean RIJV diameter was significantly greater in all positions (p < 0.001) except for the reverse Trendelenburg position. The greatest increase in diameter was observed in the Trendelenburg position with the Valsalva manoeuvre (p < 0.001). CONCLUSION In paediatric patients, the application of the Trendelenburg position with the Valsalva manoeuvre gave the greatest increase in RIJV diameter. The reverse Trendelenburg position had no significant effect on RIJV diameter. PMID:25597750

  16. Using Ultrasonography to Determine Optimal Head-down Tilt Position Angle in Patients before Catheterization of the Internal Jugular Vein

    PubMed Central

    Kasatkin, Anton A.; Urakov, Aleksandr L.; Nigmatullina, Anna R.

    2017-01-01

    Context: It is believed that 15°–25° head-down tilt position increases the internal jugular vein cross-sectional area (IJV CSA). The increase in IJV CSA before puncture reduces the risk of its perforation. This pattern was not observed in all patients. We assumed that the absence of respiratory-based IJV excursion is one of the criteria of head-down tilt position effectiveness. Aims: The aim of this study is to determine the head-down tilt angle, which ensures the absence of the respiratory-based IJV excursion. Subjects and Methods: Prospective study included twenty adult patients. The IJVs scanning was carried out in 1 min after placing the patients in a horizontal position on their back and in 1 min after placing them in the head-down tilt position at 5°, 10°, 15°, and 20° tilt angles. Results: We found that collapsibility index of <9% indicating the absence of respiratory-based IJV excursion was recorded in 25% of patients in the horizontal supine position. In this case, placing the patients in the Trendelenburg position for IJV catheterization may not be indicated. In 65% of the patients, the respiratory-based excursion was not observed at 10° head-down tilt position. Only 35% of the patients required 15° head-down tilt position. Conclusions: In clinical settings, the disappearance of respiratory-based vein excursion on the ultrasound scanner screen can be considered as criteria of the head-down tilt position effectiveness.

  17. Incidence of posterior wall penetration during internal jugular vein cannulation: A comparison of two techniques using real-time ultrasound

    PubMed Central

    Srinivasan, Shrikanth; Govil, Deepak; Gupta, Sachin; Patel, Sweta; Jagadeesh, KN; Tomar, Deeksha Singh

    2017-01-01

    Background and Aims: The true incidence of penetration of the posterior wall (through-and-through puncture) of the internal jugular vein (IJV) during cannulation is unknown. This may have implications if there is hematoma formation, penetration and/or inadvertent cannulation of an underlying carotid artery. This study compared the incidence of posterior wall puncture during IJV cannulation using ultrasound guidance versus traditional landmarks-guided technique. Methods: One hundred and seventy adult patients admitted to a gastro-liver Intensive Care Unit who required central venous lines were randomly divided into Group A: IJV cannulation using anatomical landmark-guided technique and Group B: IJV cannulation using real-time ultrasound guidance. In both groups, a second investigator followed the needle path using real-time ultrasound. The incidence of posterior wall puncture, number of attempts for successful cannulation, incidence of inadvertent arterial punctures and occurrence of complications such as hematoma formation and pneumothorax were recorded. Results: Significantly more (37/80, 46%) patients in Group A had posterior wall puncture compared to 19/90 (21%) in Group B. Incidence of arterial puncture was 8/80 (10%) in Group A, 5/90 (5.5%) in Group B. The number of attempts for venous cannulation and hematoma formation was significantly less in Group B. Conclusion: Real-time ultrasound-guided IJV cannulation significantly reduces but does not wholly eliminate the incidence of posterior venous wall penetrations. It also significantly reduces the incidence of inadvertent arterial punctures and number of attempts for successful cannulation.

  18. Moderate hypothermia suppresses jugular venous superoxide anion radical, oxidative stress, early inflammation, and endothelial injury in forebrain ischemia/reperfusion rats.

    PubMed

    Koda, Yoichi; Tsuruta, Ryosuke; Fujita, Motoki; Miyauchi, Takashi; Kaneda, Kotaro; Todani, Masaki; Aoki, Tetsuya; Shitara, Masaki; Izumi, Tomonori; Kasaoka, Shunji; Yuasa, Makoto; Maekawa, Tsuyoshi

    2010-01-22

    The aim of this study was to assess the effect of moderate hypothermia (MH) on generation of jugular venous superoxide radical (O2-.), oxidative stress, early inflammation, and endothelial injury in forebrain ischemia/reperfusion (FBI/R) rats. Twenty-one Wistar rats were allocated to a control group (n=7, 37 degrees C), a pre-MH group (n=7, 32 degrees C before ischemia), and a post-MH group (n=7, 32 degrees C after reperfusion). MH was induced before induction of ischemia in the pre-MH group and just after reperfusion in the post-MH group. Forebrain ischemia was induced by occlusion of bilateral common carotid arteries with hemorrhagic hypotension for 10 min, followed by reperfusion. O(2)(-)(.) in the jugular vein was measured from the produced current using a novel O2-. sensor. The O2-. current showed a gradual increase during forebrain ischemia in the control and post-MH groups but was attenuated in the pre-MH group. Following reperfusion, the current showed a marked increase in the control group but was strongly attenuated in the pre- and post-MH groups. Concentrations of malondialdehyde, high-mobility group box 1 (HMGB1) protein, and intercellular adhesion molecule-1 (ICAM-1) in the brain and plasma 120 min after reperfusion in the pre- and post-MH groups were significantly lower than those in the control group, except for plasma HMGB1 in the post-MH group. In conclusion, MH suppressed O2-. measured in the jugular vein, oxidative stress, early inflammation, and endothelial injury in FBI/R rats.

  19. Catheter venography for the assessment of internal jugular veins and azygous vein: position statement by expert panel of the International Society for Neurovascular Disease.

    PubMed

    Simka, Marian; Hubbard, David; Siddiqui, Adnan H; Dake, Michael D; Sclafani, Salvatore J A; Al-Omari, Mamoon; Eisele, Carlos G; Haskal, Ziv J; Ludyga, Tomasz; Miloševič, Zoran V; Sievert, Horst; Stehling, Michael K; Zapf, Stefan; Zorc, Marjeta

    2013-05-01

    This document by an expert panel of the International Society for Neurovascular Disease is aimed at presenting current technique and interpretation of catheter venography of the internal jugular veins, azygous vein and other veins draining the central nervous system. Although interventionalists agree on general rules, significant differences exist in terms of details of venographic technique and interpretations of angiographic pictures. It is also suggested that debatable findings should be investigated using multimodal diagnostics. Finally, the authors recommend that any publication on chronic cerebrospinal venous insufficiency should include detailed description of venographic technique used, to facilitate a comparison of published results in this area.

  20. Glomus jugulare tumor

    MedlinePlus

    ... the part of the temporal bone in the skull that involves the middle and inner ear structures. ... affect the ear, upper neck, base of the skull, and the surrounding blood vessels and nerves. Causes ...

  1. Pulmonary embolism and internal jugular vein thrombosis as evocative clues of Lemierre’s syndrome: A case report and review of the literature

    PubMed Central

    De Giorgi, Alfredo; Fabbian, Fabio; Molino, Christian; Misurati, Elisa; Tiseo, Ruana; Parisi, Claudia; Boari, Benedetta; Manfredini, Roberto

    2017-01-01

    Lemierre’s syndrome (LS) is an uncommon condition with oropharyngeal infections, internal jugular vein thrombosis, and systemic metastatic septic embolization as the main features. Fusobacterium species, a group of strictly anaerobic Gram negative rod shaped bacteria, are advocated to be the main pathogen involved. We report a case of LS complicated by pulmonary embolism and pulmonary septic emboli that mimicked a neoplastic lung condition. A Medline search revealed 173 case reports of LS associated with internal jugular vein thrombosis that documented the type of microorganism. Data confirmed high prevalence in young males with Gram negative infections (83.2%). Pulmonary embolism was reported in 8.7% of cases mainly described in subjects with Gram positive infections (OR = 9.786; 95%CI: 2.577-37.168, P = 0.001), independently of age and gender. Only four fatal cases were reported. LS is an uncommon condition that could be complicated by pulmonary embolism, especially in subjects with Gram positive infections. PMID:28352635

  2. Complex Adaptive System of Systems (CASoS) Engineering Applications. Version 1.0.

    SciTech Connect

    Linebarger, John Michael; Maffitt, S. Louise; Glass, Robert John, Jr.; Beyeler, Walter Eugene; Brown, Theresa Jean; Ames, Arlo Leroy

    2011-10-01

    Complex Adaptive Systems of Systems, or CASoS, are vastly complex eco-socio-economic-technical systems which we must understand to design a secure future for the nation and the world. Perturbations/disruptions in CASoS have the potential for far-reaching effects due to highly-saturated interdependencies and allied vulnerabilities to cascades in associated systems. The Phoenix initiative approaches this high-impact problem space as engineers, devising interventions (problem solutions) that influence CASoS to achieve specific aspirations. CASoS embody the world's biggest problems and greatest opportunities: applications to real world problems are the driving force of our effort. We are developing engineering theory and practice together to create a discipline that is grounded in reality, extends our understanding of how CASoS behave, and allows us to better control those behaviors. Through application to real-world problems, Phoenix is evolving CASoS Engineering principles while growing a community of practice and the CASoS engineers to populate it.

  3. Phoenix : Complex Adaptive System of Systems (CASoS) engineering version 1.0.

    SciTech Connect

    Moore, Thomas W.; Quach, Tu-Thach; Detry, Richard Joseph; Conrad, Stephen Hamilton; Kelic, Andjelka; Starks, Shirley J.; Beyeler, Walter Eugene; Brodsky, Nancy S.; Verzi, Stephen J.; Brown, Theresa Jean; Glass, Robert John, Jr.; Sunderland, Daniel J.; Mitchell, Michael David; Ames, Arlo Leroy; Maffitt, S. Louise; Finley, Patrick D.; Russell, Eric Dean; Zagonel, Aldo A.; Reedy, Geoffrey E.; Mitchell, Roger A.; Corbet, Thomas Frank, Jr.; Linebarger, John Michael

    2011-08-01

    Complex Adaptive Systems of Systems, or CASoS, are vastly complex ecological, sociological, economic and/or technical systems which we must understand to design a secure future for the nation and the world. Perturbations/disruptions in CASoS have the potential for far-reaching effects due to pervasive interdependencies and attendant vulnerabilities to cascades in associated systems. Phoenix was initiated to address this high-impact problem space as engineers. Our overarching goals are maximizing security, maximizing health, and minimizing risk. We design interventions, or problem solutions, that influence CASoS to achieve specific aspirations. Through application to real-world problems, Phoenix is evolving the principles and discipline of CASoS Engineering while growing a community of practice and the CASoS engineers to populate it. Both grounded in reality and working to extend our understanding and control of that reality, Phoenix is at the same time a solution within a CASoS and a CASoS itself.

  4. Complex Adaptive Systems of Systems (CASoS) engineering and foundations for global design.

    SciTech Connect

    Brodsky, Nancy S.; Finley, Patrick D.; Beyeler, Walter Eugene; Brown, Theresa Jean; Linebarger, John Michael; Moore, Thomas W.; Glass, Robert John, Jr.; Maffitt, S. Louise; Mitchell, Michael David; Ames, Arlo Leroy

    2012-01-01

    Complex Adaptive Systems of Systems, or CASoS, are vastly complex ecological, sociological, economic and/or technical systems which must be recognized and reckoned with to design a secure future for the nation and the world. Design within CASoS requires the fostering of a new discipline, CASoS Engineering, and the building of capability to support it. Towards this primary objective, we created the Phoenix Pilot as a crucible from which systemization of the new discipline could emerge. Using a wide range of applications, Phoenix has begun building both theoretical foundations and capability for: the integration of Applications to continuously build common understanding and capability; a Framework for defining problems, designing and testing solutions, and actualizing these solutions within the CASoS of interest; and an engineering Environment required for 'the doing' of CASoS Engineering. In a secondary objective, we applied CASoS Engineering principles to begin to build a foundation for design in context of Global CASoS

  5. Evaluation of pulsatility index and diameter of the jugular vein and superficial body temperature as physiological indices of temperament in weaned beef calves: relationship with serum cortisol concentrations, rectal temp..

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The relationship between temperament, pulsatility index and diameter of the jugular vein, and body temperature was assessed in Angus crossbred calves (262±24.9 days old). Temperament scores were used to classify calves as calm (n=31), intermediate (n=32), or temperamental (n=28). Blood samples were ...

  6. Effects of Hypothermic Cardiopulmonary Bypass on Internal Jugular Bulb Venous Oxygen Saturation, Cerebral Oxygen Saturation, and Bispectral Index in Pediatric Patients Undergoing Cardiac Surgery: A Prospective Study.

    PubMed

    Hu, Zhiyong; Xu, Lili; Zhu, Zhirui; Seal, Robert; McQuillan, Patrick M

    2016-01-01

    The objective of this study was to evaluate the effect of hypothermic cardiopulmonary bypass (CPB) on cerebral oxygen saturation (rSO2), internal jugular bulb venous oxygen saturation (SjvO2), mixed venous oxygen saturation (SvO2), and bispectral index (BIS) used to monitor cerebral oxygen balance in pediatric patients.Sixty American Society of Anesthesiologists Class II-III patients aged 1 to 4 years old with congenital heart disease scheduled for elective cardiac surgery were included in this study. Temperature, BIS, rSO2, mean arterial pressure, central venous pressure, cerebral perfusion pressure (CPP), and hematocrit were recorded. Internal jugular bulb venous oxygen saturation and SvO2 were obtained from blood gas analysis at the time points: after induction of anesthesia (T0), beginning of CPB (T1), ascending aortic occlusion (T2), 20 minutes after initiating CPB (T3), coronary reperfusion (T4), separation from CPB (T5), and at the end of operation (T6). The effect of hypothermia or changes in CPP on rSO2, SjvO2, SvO2, and BIS were analyzed.Compared with postinduction baseline values, rSO2 significantly decreased at all-time points: onset of extracorporeal circulation, ascending aortic occlusion, 20 minutes after CPB initiation, coronary reperfusion, and separation from CPB (P < 0.05). Compared with measurements made following induction of anesthesia, SjvO2 significantly increased with initiation of CPB, ascending aortic occlusion, 20 minutes after initiating CPB, coronary reperfusion, and separation from CPB (P < 0.05). Compared with induction of anesthesia, BIS significantly decreased with the onset of CPB, aortic cross clamping, 20 minutes after initiating CPB, and coronary reperfusion (P < 0.05). Bispectral index increased following separation from CPB. There was no significant change in SvO2 during cardiopulmonary bypass (P > 0.05). Correlation analysis demonstrated that rSO2 was positively related to CPP (r = 0.687, P = 0

  7. Perforation of the superior vena cava 5 days after insertion of a central venous catheter through the left internal jugular vein.

    PubMed

    Kurabe, Miyuki; Watanabe, Tatsunori; Kohno, Tatsuro

    2016-06-01

    We describe a very rare case of an indwelling central venous catheter (CVC) through the left internal jugular vein that perforated the superior vena cava (SVC) wall postoperatively, although the CVC was placed in the appropriate position preoperatively. Three days after CVC insertion, a chest radiograph showed that the CVC tip had moved from the lower SVC to the upper SVC. Five days after the insertion, computed tomography showed SVC perforation and the resulting hydrothorax. In cases of CVC insertion through the left side, the CVC tip should not be placed in the upper SVC (zone B). Considering individual clinical factors and the indwelling period for the CVC, the left innominate vein (zone C) may be a suitable site for the left-sided CVC tip to reduce the risk of SVC perforation.

  8. Inhibitory effect of sustained perivascular delivery of paclitaxel on neointimal hyperplasia in the jugular vein after open cutdown central venous catheter placement in rats

    PubMed Central

    Kim, Seongyup; Kim, Younglim; Hwang, Ji Woong

    2017-01-01

    Purpose Inhibitory effect of paclitaxel on neointimal hyperplasia after open cutdown has not been elucidated. Methods For the control group (n = 16), silicone 2.7-Fr catheters were placed via the right external jugular vein with the cutdown method. For the treatment group (n = 16), a mixture of 0.65 mg of paclitaxel and 1 mL of fibrin glue was infiltrated around the exposed vein after cutdown. After scheduled intervals (1, 2, 4, and 8 weeks), the vein segment was harvested and morphometric analysis was performed on cross-sections. Results Proliferation of smooth muscle cell (SMC) was strongly suppressed in the treatment group, and the ratio of neointima to vein wall was significantly reduced in the treatment group (8 weeks; 0.63 ± 0.08 vs. 0.2 ± 0.08, P < 0.05). Luminal patency was significantly more preserved in the treatment group, and the luminal area was significantly wider in the paclitaxel-treated group compared to the control group (8 weeks; 1.91 ± 0.43 mm2 vs. 5.1 ± 0.43 mm2, P < 0.05). Mean SMC counts measured at 1 and 2 weeks after cutdown were significantly lower in the treatment group (2 weeks; 115 ± 22 vs. 62 ± 22). Paclitaxel was undetectable in systemic circulation (<10 ng/mL). Conclusion Sustained perivascular delivery of paclitaxel with fibrin glue was effective in inhibiting neointimal hyperplasia in rat jugular vein after open cutdown. PMID:28203557

  9. Elevation of jugular venous superoxide anion radical is associated with early inflammation, oxidative stress, and endothelial injury in forebrain ischemia-reperfusion rats.

    PubMed

    Aki, Hiromi Shinagawa; Fujita, Motoki; Yamashita, Susumu; Fujimoto, Kenji; Kumagai, Kazumi; Tsuruta, Ryosuke; Kasaoka, Shunji; Aoki, Tetsuya; Nanba, Masahiro; Murata, Hidenori; Yuasa, Makoto; Maruyama, Ikuro; Maekawa, Tsuyoshi

    2009-10-06

    A novel electrochemical sensor was used in this study to determine the correlations between jugular venous O(2)(-) and HMGB1, malondialdehyde (MDA), and intercellular adhesion molecule-1 (ICAM-1) in rats with forebrain ischemia/reperfusion (FBI/R). Twenty-one male rats were divided into a Sham group, a hemorrhagic shock/reperfusion (HS/R) group, and a forebrain ischemia/reperfusion (FBI/R) group. The O(2)(-) sensor in the jugular vein detected the current derived from O(2)(-) generation (abbreviated as "O(2)(-) current"), which was integrated as the partial value of quantified electricity during ischemia (Q(I)) and after reperfusion (Q(R)). The plasma O(2)(-) current showed a gradual increase during forebrain ischemia in the HS/R and the FBI/R groups. The current showed a marked increase immediately after reperfusion and continued for more than 60 min in the FBI/R group. In the HS/R group, the current was gradually attenuated to the baseline level. Brain and plasma HMGB1 increased significantly in the FBI/R group compared with those in the Sham and the HS/R groups, and both brain and plasma HMGB1 correlated significantly with the sum of Q(I) and Q(R) (total Q). Brain and plasma MDA and plasma soluble ICAM-1 also correlated significantly with total Q. Here, we report the correlation between O(2)(-) and HMGB1, MDA, and sICAM-1 in rats with cerebral ischemia-reperfusion, using a novel electrochemical sensor. These data indicated that excessive production of O(2)(-) after ischemia-reperfusion was associated with early inflammation, oxidative stress, and endothelial activation in the brain and plasma, which might enhance the ischemia-reperfusion injury.

  10. Complex Adaptive Systems of Systems (CASOS) engineering environment.

    SciTech Connect

    Detry, Richard Joseph; Linebarger, John Michael; Finley, Patrick D.; Maffitt, S. Louise; Glass, Robert John, Jr.; Beyeler, Walter Eugene; Ames, Arlo Leroy

    2012-02-01

    Complex Adaptive Systems of Systems, or CASoS, are vastly complex physical-socio-technical systems which we must understand to design a secure future for the nation. The Phoenix initiative implements CASoS Engineering principles combining the bottom up Complex Systems and Complex Adaptive Systems view with the top down Systems Engineering and System-of-Systems view. CASoS Engineering theory and practice must be conducted together to develop a discipline that is grounded in reality, extends our understanding of how CASoS behave and allows us to better control the outcomes. The pull of applications (real world problems) is critical to this effort, as is the articulation of a CASoS Engineering Framework that grounds an engineering approach in the theory of complex adaptive systems of systems. Successful application of the CASoS Engineering Framework requires modeling, simulation and analysis (MS and A) capabilities and the cultivation of a CASoS Engineering Community of Practice through knowledge sharing and facilitation. The CASoS Engineering Environment, itself a complex adaptive system of systems, constitutes the two platforms that provide these capabilities.

  11. Prevalence and impact of incompetence of internal jugular valve on postoperative cognitive dysfunction in elderly patients undergoing robot-assisted laparoscopic radical prostatectomy.

    PubMed

    Roh, Go Un; Kim, Won Oak; Rha, Koon Ho; Lee, Byung Ho; Jeong, Hae Won; Na, Sungwon

    2016-01-01

    Internal jugular vein (IJV) is the main pathway of cerebral venous drainage and its valves prevent regurgitation of blood to the brain. IJV valve incompetence (IJVVI) is known to be associated with cerebral dysfunctions. It occurs more often in male over 50 years old, conditions elevating intra-abdominal or intra-thoracic pressure. In robot-assisted laparoscopic radical prostatectomy (RALRP), elderly male undergoes surgery in Trendelenburg position with pneumoperitoneum applied. Therefore, we assessed the IJVVI during RALRP and its influence on postoperative cognitive function. 57 patients undergoing RALRP were enrolled. Neurocognitive tests including Mini-Mental State Examination (MMSE), Auditory Verbal Learning Test, Digit Symbol Substitution Test, Color Word Stroop Test, digit span test, and grooved pegboard test were performed the day before and 2 days after surgery. During surgery, IJVVI was assessed with ultrasonography in supine position with and without pneumoperitoneum, and Trendelenburg position with pneumoperitoneum. 50 patients underwent sonographic assessment and 41 patients completed neurocognitive examination. A total of 27 patients presented IJVVI, 19 patients in supine position without pneumoperitoneum, 7 patients in supine position with pneumoperitoneum and 1 patient in Trendelenburg position with pneumoperitoneum. In neurocognitive tests, patients with IJVVI showed statistically significant decline of score in MMSE postoperatively (p<0.05). IJVVI occurred in 38% in supine position but the incidence was increased to 54% after Trendelenburg position and pneumoperitoneum. Patients with IJVVI did not show significant differences in cognitive function tests except MMSE. Clinical and neurological significance of physiologic changes associated RALRP should be studied further.

  12. Comparison of Brachial Vein Versus Internal Jugular Vein Approach for Access to the Right Side of the Heart With or Without Myocardial Biopsy.

    PubMed

    Harwani, Neha; Chukwu, Ebere; Alvarez, Manrique; Thohan, Vinay

    2015-09-01

    Right heart catheterization (RHC) and endomyocardial biopsy are mainstay procedures for patients with heart failure and heart transplantation. Approaches are predominantly neck (internal jugular) or leg (femoral vein). We describe a novel arm (brachial/basilica vein) approach. Over 5.5 years, 1,130 right-sided cardiac procedures in 276 patients were analyzed retrospectively and divided into either neck or arm approach. Comparative analyses of procedural success, time, safety, efficacy, and cost were performed. Patient preference was assessed for those who had both neck and arm approaches. In patients receiving RHC (174 neck and 121 arm cases) and in those receiving RHC + biopsy (594 neck and 141 arm cases), mean elapsed and fluoroscopic times (minutes), respectively, were 60 ± 20 versus 62 ± 19 and 3.43 ± 3.8 versus 4.99 ± 5.2 (RHC neck vs arm, respectively), and 55 ± 19 versus 63 ± 17 and 4.14 ± 3.4 versus 5.22 ± 2.6 (RHC + biopsy neck vs arm, respectively). Procedural complications were low (n = 7, 0.6%) and restricted to the neck approach. Patients surveyed preferred the arm approach. In conclusion, RHC and endomyocardial biopsy through the brachial vein can be performed safely, timely, effectively, and at equivalent cost compared with a neck approach. We advocate that an arm approach be the preferred method for these procedures.

  13. Massive hemothorax due to subclavian vein tear during internal jugular vein cannulation in a 15-year-old boy scheduled for mitral valve replacement

    PubMed Central

    Mishra, Sandeep Kumar; Paulose, Deepak; Kundra, Pankaj; Parida, Satyen

    2015-01-01

    We present an unusual case of life-threatening hemothorax in a 15-year-old boy following subclavian vein tear during internal jugular vein (IJV) cannulation prior to initiation of surgery (mitral valve replacement). Successful IJV cannulation was done in the third attempt. However, we missed the subclavian tear which occurred during the first two initial attempts as there was no clinical evidence suggestive of it at that point of time. This undiagnosed hemothorax led to hemodynamic decompensation requiring high volume and inotropic support to wean the patient off cardiopulmonary bypass. This unusually high requirement of fluid and inotropes required the surgeon to look for noncardiac causes for the hemodynamic disturbance and he noticed a bulge in the right pleura, which on exploration had approximately 1.5 L of collected blood. It was then retrospectively analyzed that the cause of this hemothorax could have been the undue lateral orientation of the needle during IJV cannulation and the advancement of the dilator to its entire length could have injured the subclavian vein. Here, we also would like to discuss the safety precautions to be taken during the cannulation, like the needle orientation and the length to which the dilator must be advanced for safe central venous cannulation. PMID:26712992

  14. Um Infixation and Prefixation in Toba Batak.

    ERIC Educational Resources Information Center

    Crowhurst, Megan J.

    1998-01-01

    Examines the behavior of the morpheme, um, in Toba Batak and Tagalog, which alternates as a prefix or an infix, arguing that the variation is conditioned by constraints on consonant clusters. Three patterns of variation that occur with um are described, noting that the stages involved in changing from infixed to prefixed positions over time are…

  15. Effects of the Trendelenburg Position and Positive End-Expiratory Pressure on the Internal Jugular Vein Cross-Sectional Area in Children With Simple Congenital Heart Defects

    PubMed Central

    Kim, Hee Yeong; Choi, Jae Moon; Lee, Yong-Hun; Lee, Sukyung; Yoo, Hwanhee; Gwak, Mijeung

    2016-01-01

    Abstract Catheterization of the internal jugular vein (IJV) remains difficult in pediatric populations. Increasing the cross-sectional area (CSA) of the IJV facilitates cannulation and decreases complications. We aimed to evaluate the Trendelenburg position and the levels of positive end-expiratory pressure (PEEP) at which the maximum increase of CSA of the IJV occurred in children undergoing cardiac surgery. In this prospective study, the CSA of the right IJV was assessed using ultrasound in 47 anesthetized pediatric patients with simple congenital heart defects. The baseline CSA was obtained in response to a supine position with no PEEP and compared with 5 different randomly ordered maneuvers, that is, a PEEP of 5 and 10 cm H2O in a supine position and of 0, 5, and 10 cm H2O in a 10° Trendelenburg position. Hemodynamic variables, including blood pressure and heart rate, maximum and minimum diameters, and CSA, were measured. All maneuvers increased the CSA of the right IJV with respect to the control condition. In the supine position, the CSA was increased by 9.4% with a PEEP of 5 and by 19.5% with a PEEP of 10 cm H2O. The Trendelenburg tilt alone increased the CSA by 19.0%, and combining the 10° Trendelenburg with a 10 cm H2O PEEP resulted in the largest IJV CSA increase (33.3%) compared with the supine position with no PEEP. Meanwhile, vital signs remained relatively steady during the experiment. The application of the Trendelenburg position and a 10 cm H2O PEEP thus significantly increases the CSA of the right IJV, perhaps improving the chances of successful cannulation in pediatric patients with simple congenital heart defects. PMID:27149455

  16. Effects of the Trendelenburg Position and Positive End-Expiratory Pressure on the Internal Jugular Vein Cross-Sectional Area in Children With Simple Congenital Heart Defects.

    PubMed

    Kim, Hee Yeong; Choi, Jae Moon; Lee, Yong-Hun; Lee, Sukyung; Yoo, Hwanhee; Gwak, Mijeung

    2016-05-01

    Catheterization of the internal jugular vein (IJV) remains difficult in pediatric populations. Increasing the cross-sectional area (CSA) of the IJV facilitates cannulation and decreases complications. We aimed to evaluate the Trendelenburg position and the levels of positive end-expiratory pressure (PEEP) at which the maximum increase of CSA of the IJV occurred in children undergoing cardiac surgery.In this prospective study, the CSA of the right IJV was assessed using ultrasound in 47 anesthetized pediatric patients with simple congenital heart defects. The baseline CSA was obtained in response to a supine position with no PEEP and compared with 5 different randomly ordered maneuvers, that is, a PEEP of 5 and 10 cm H2O in a supine position and of 0, 5, and 10 cm H2O in a 10° Trendelenburg position. Hemodynamic variables, including blood pressure and heart rate, maximum and minimum diameters, and CSA, were measured.All maneuvers increased the CSA of the right IJV with respect to the control condition. In the supine position, the CSA was increased by 9.4% with a PEEP of 5 and by 19.5% with a PEEP of 10 cm H2O. The Trendelenburg tilt alone increased the CSA by 19.0%, and combining the 10° Trendelenburg with a 10 cm H2O PEEP resulted in the largest IJV CSA increase (33.3%) compared with the supine position with no PEEP. Meanwhile, vital signs remained relatively steady during the experiment.The application of the Trendelenburg position and a 10 cm H2O PEEP thus significantly increases the CSA of the right IJV, perhaps improving the chances of successful cannulation in pediatric patients with simple congenital heart defects.

  17. Analysis of head impact exposure and brain microstructure response in a season-long application of a jugular vein compression collar: a prospective, neuroimaging investigation in American football

    PubMed Central

    Myer, Gregory D; Yuan, Weihong; Barber Foss, Kim D; Thomas, Staci; Smith, David; Leach, James; Kiefer, Adam W; Dicesare, Chris; Adams, Janet; Gubanich, Paul J; Kitchen, Katie; Schneider, Daniel K; Braswell, Daniel; Krueger, Darcy; Altaye, Mekibib

    2016-01-01

    Background Historical approaches to protect the brain from outside the skull (eg, helmets and mouthpieces) have been ineffective in reducing internal injury to the brain that arises from energy absorption during sports-related collisions. We aimed to evaluate the effects of a neck collar, which applies gentle bilateral jugular vein compression, resulting in cerebral venous engorgement to reduce head impact energy absorption during collision. Specifically, we investigated the effect of collar wearing during head impact exposure on brain microstructure integrity following a competitive high school American football season. Methods A prospective longitudinal controlled trial was employed to evaluate the effects of collar wearing (n=32) relative to controls (CTRL; n=30) during one competitive football season (age: 17.04±0.67 years). Impact exposure was collected using helmet sensors and white matter (WM) integrity was quantified based on diffusion tensor imaging (DTI) serving as the primary outcome. Results With similar overall g-forces and total head impact exposure experienced in the two study groups during the season (p>0.05), significant preseason to postseason changes in mean diffusivity, axial diffusivity and radial diffusivity in the WM integrity were noted in the CTRL group (corrected p<0.05) but not in the collar group (p>0.05). The CTRL group demonstrated significantly larger preseason to postseason DTI change in multiple WM regions compared with the collar group (corrected p<0.05). Discussion Reduced WM diffusivity alteration was noted in participants wearing a neck collar after a season of competitive football. Collar wearing may have provided a protective effect against brain microstructural changes after repetitive head impacts. Trial registration number NCT02696200. PMID:27307271

  18. Emergent Median Sternotomy for Mediastinal Hematoma: A Rare Complication following Internal Jugular Vein Catheterization for Chemoport Insertion—A Case Report and Review of Relevant Literature

    PubMed Central

    Biswas, Saptarshi

    2014-01-01

    Mediastinal hematoma is a rare complication following insertion of a central venous catheter with only few cases reported in the English literature. We report a case of a 71-year-old female who was admitted for elective chemoport placement. USG guided right internal jugular access was attempted using the Seldinger technique. Resistance was met while threading the guidewire. USG showed a chronic clot burden in the RIJ. A microvascular access was established under fluoroscopic guidance. Rest of the procedure was completed without any further issues. Following extubation, the patient complained of right-sided chest pain radiating to the back. Chest X-ray revealed a contained white out in the right upper lung field. She became hemodynamically unstable. Repeated X-ray showed progression of the hematoma. Median Sternotomy showed posterior mediastinal hematoma tracking into right pleural cavity. Active bleeding from the puncture site at RIJ-SCL junction was repaired. Patient had an uneventful recovery. Injury to the central venous system is the result of either penetrating trauma or iatrogenic causes as in our case. A possible explanation of our complication may be attributed to the forced manipulation of the dilator or guidewire against resistance. Clavicle and sternum offer bony protection to the underlying vital venous structures and injuries often need sternotomy with or without neck extension. Division of the clavicle and disarticulation of the sternoclavicular joint may be required for optimum exposure. Meticulous surgical technique, knowledge of the possible complications, and close monitoring in the postprocedural period are of utmost importance. Chest X-ray showed to be routinely done to detect any complication early. PMID:24592335

  19. Late-onset congestive heart failure in a patient with a 58-year-old huge traumatic carotid-jugular fistula and pseudoaneurysm: endovascular treatment with a stent-graft.

    PubMed

    Kong, Joon Hyuk; Park, Sang Min; Kim, Tae Hoon; Choi, Dong Hoon; Lee, Do Yun

    2010-10-01

    We report a case of successful stent-graft endovascular treatment of a huge traumatic carotid-jugular fistula with a pseudoaneurysm that had resulted from a bullet injury. A 77-year-old man with a pulsatile neck mass came to our hospital complaining of dyspnea and chest pain at rest; about 58 years ago, a gunshot accident had inflicted a penetrating bullet wound on the right side of his neck. Computerized tomography angiogram had demonstrated a huge vascular mass protruding into the right anterior neck with a pseudoaneurysm. The calcified pseudoaneurysm had an oval-shaped opening in the right common carotid artery, with a large base into the right internal jugular vein. Echocardiography showed deteriorating congestive heart failure, wherein left ventricular (LV) enlargement with a LV end-diastolic diameter of 6.1 cm, severe tricuspid valve regurgitation, and LV ejection fraction of 60% was seen. The surgical approach was considered risky because of the severe deformity of the native vasculature, the severe calcified pseudoaneurysm, and the context of advanced age with congestive heart failure. Thus, we decided to treat this patient with endovascular devices. Fortunately, a stent-graft was delivered successfully across the carotid-jugular fistula and immediate follow-up angiogram demonstrated a small filling defect at the base of stent-graft representing thrombus. The follow-up computerized tomography angiograms obtained 2 weeks and 4 months later further demonstrated a patent stent-graft, no evidence of thrombus progression, and no abnormal shunt flow. The patient did not experience any neurologic complications nor did he show any evidence of pulmonary embolism for 8 months.

  20. The anatomical perspective of human occipital condyle in relation to the hypoglossal canal, condylar canal, and jugular foramen and its surgical significance

    PubMed Central

    Verma, Ranjana; Kumar, Shalini; Rai, Arpita Mahajan; Mansoor, Iqra; Mehra, Raj D

    2016-01-01

    Background: The transcondylar approach (TCA) has gained importance in recent era which enables shorter and direct route to access the lesions ventral to the brainstem. The important step in this approach is resection of the occipital condyle (OC). The detailed knowledge of bony anatomy of OC and its relation to the hypoglossal canal (HC), condylar canal (CC), and jugular foramen (JF) is very important to avoid any iatrogenic injury during craniovertebral surgeries. The aim of the present study is to conduct a morphometric and morphological study and note the variations of the OC and the structures surrounding it in North Indian population. Materials and Methods: The study was carried out on 100 OC. Morphometric measurements of OC and the distances of HC and JF from the posterior end of OC were noted. In addition, the extent of the HC and JF in relation to OC, presence or absence of CC, shape of the OC, and its articular facet were also noted. Results: The incidence of short OC was seen in 13% skulls. The most common shape of OC was oval or rhomboid. Even though the articular facet was convex in majority of skulls but flat (10%) and concave (1%) were also observed. The external and internal distance of HC from the posterior end of OC was13.83 mm and 10.66 mm on the right side and 15.02 mm and 11.89 mm on the left side. The OC was related in its middle 1/3 to the HC in 15% skulls and to the whole extent of JF in 3% skulls. Thirty-four percent skulls displayed the septa in the HC. The CC was present bilaterally in 38% skulls and unilaterally in 40% skulls. Conclusion: The OC and related structures such as HC, CC, and JF are likely to have variations in respect to morphometry and morphology. This study may prove helpful to neurosurgeons operating in this field, especially during TCA where neurovascular structures emerging from these canals and foramen are more vulnerable to injury. PMID:27891034

  1. Internal Jugular Vein Cross-Sectional Area and Cerebrospinal Fluid Pulsatility in the Aqueduct of Sylvius: A Comparative Study between Healthy Subjects and Multiple Sclerosis Patients

    PubMed Central

    Beggs, Clive B.; Magnano, Christopher; Belov, Pavel; Krawiecki, Jacqueline; Ramasamy, Deepa P.; Hagemeier, Jesper; Zivadinov, Robert

    2016-01-01

    Objectives Constricted cerebral venous outflow has been linked with increased cerebrospinal fluid (CSF) pulsatility in the aqueduct of Sylvius in multiple sclerosis (MS) patients and healthy individuals. This study investigates the relationship between CSF pulsatility and internal jugular vein (IJV) cross-sectional area (CSA) in these two groups, something previously unknown. Methods 65 relapsing-remitting MS patients (50.8% female; mean age = 43.8 years) and 74 healthy controls (HCs) (54.1% female; mean age = 43.9 years) were investigated. CSF flow quantification was performed on cine phase-contrast MRI, while IJV-CSA was calculated using magnetic resonance venography. Statistical analysis involved correlation, and partial least squares correlation analysis (PLSCA). Results PLSCA revealed a significant difference (p<0.001; effect size = 1.072) between MS patients and HCs in the positive relationship between CSF pulsatility and IJV-CSA at C5-T1, something not detected at C2-C4. Controlling for age and cardiovascular risk factors, statistical trends were identified in HCs between: increased net positive CSF flow (NPF) and increased IJV-CSA at C5-C6 (left: r = 0.374, p = 0.016; right: r = 0.364, p = 0.019) and C4 (left: r = 0.361, p = 0.020); and increased net negative CSF flow and increased left IJV-CSA at C5-C6 (r = -0.348, p = 0.026) and C4 (r = -0.324, p = 0.039), whereas in MS patients a trend was only identified between increased NPF and increased left IJV-CSA at C5-C6 (r = 0.351, p = 0.021). Overall, correlations were weaker in MS patients (p = 0.015). Conclusions In healthy adults, increased CSF pulsatility is associated with increased IJV-CSA in the lower cervix (independent of age and cardiovascular risk factors), suggesting a biomechanical link between the two. This relationship is altered in MS patients. PMID:27135831

  2. Parylene supported 20um*20um uncooled thermoelectric infrared detector with high fill factor

    NASA Astrophysics Data System (ADS)

    Modarres-Zadeh, Mohammad J.; Carpenter, Zachary S.; Rockley, Mark G.; Abdolvand, Reza

    2012-06-01

    Presented is a novel design for an uncooled surface-micromachined thermoelectric (TE) infrared (IR) detector. The detector features a P-doped polysilicon/Nichrome (Cr20-Ni80) thermocouple, which is embedded into a thin layer of Parylene-N to provide structural support. The low thermal conductivity (~0.1W/m.K), chemical resistance, and ease of deposition/patterning of Parylene-N make it an excellent choice of material for use in MEMS thermal detectors. This detector also features an umbrella-like IR absorber composed of a three layer stack of NiCr/SiN/NiCr to optimize IR absorption. The total device area is 20 um * 20 um per pixel with an absorber area of ~19 um * 19 um resulting in a fill factor of 90%. At room temperature, a DC responsivity of ~170V/W with a rise time of less than 8 ms is measured from the fabricated devices in vacuum when viewing a 500K blackbody without any concentrating optics. The dominant source of noise in thermoelectric IR detectors is typically Johnson noise when the detectors are operating in an open circuit condition. The fabricated detectors have resistances about 85KOhm which results in Johnson noise of about 38nV/Hz^0.5. The D* is calculated to be 9 * 106 cm*Hz0.5/ W. Preliminary finite element analysis indicates that the thermal conduction from the hot junction to the substrate through the TE wires is dominant ( GTE >> Gparylene) considering the fabricated dimensions of the parylene film and the TE wires. Thus, by further reducing the size of the TE wires, GTE can be decreased and hence, responsivity can be improved while the parylene film sustains the structural integrity of the cell.

  3. "Uh" and "Um" Revisited: Are They Interjections for Signaling Delay?

    ERIC Educational Resources Information Center

    O'Connell, Daniel C.; Kowal, Sabine

    2005-01-01

    Clark and Fox Tree (2002) have presented empirical evidence, based primarily on the London-Lund corpus (LL; Svartvik & Quirk, 1980), that the fillers "uh" and "um" are conventional English words that signal a speaker's intention to initiate a minor and a major delay, respectively. We present here empirical analyses of "uh" and "um" and of silent…

  4. [A clinical case of young, oral combined contraceptive using women, heterozygous carrier of the Factor V (Leiden) which revealed thrombosis of the left internal jugular vein and brain ischemia with cerebral infarction and ischemic stroke].

    PubMed

    Kovachev, S; Ramshev, K; Ramsheva, Z; Ivanov, A; Ganovska, A

    2013-01-01

    Thrombophilia is associated with increased risks of venous thrombosis in women taking oral contraceptive preparations. Universal thrombophilia screening in women prior to prescribing oral contraceptive preparations is not supported by current evidence. The case is presented of a 23 year-old women with a personal history of interruption and on the same day started with oral contraceptive (0.03 microg ethynil estradiol - 0.075 microg gestodene), which due on a 18 pill/day to acute headache, increasing vomiting and speaking defects. Physical/neurologic/gynecologic examinations observed a normal status. The MRI and CT revealed thrombosis of the left internal jugular vein and brain ischemia with cerebral infarction and ischemic stroke. The acute therapy of thrombotic findings was accompanied with many tests. The thrombophilia PCR-Real time - test finds heterozygous carrier of the Factor V (Leiden). This case shows the need of large prospective studies that should be undertaken to refine the risks and establish the associations of thrombophilias with venous thrombosis among contraceptive users. The key to a prompt diagnosis is to know the risk factors. The relative value of a thrombophilia screening programme before contraceptive using needs to be established.

  5. Infrared spectroscopic method for analysis of Mg 2Ca(SO 4) 3 in mixtures with MgSO 4 and/or CaSO 4

    NASA Astrophysics Data System (ADS)

    Smith, Duane H.; Seshadri, Kal S.

    1999-04-01

    Mg 2Ca(SO 4) 3 is prepared from, and may be found in, mixtures with MgSO 4 and CaSO 4. Such mixtures frequently occur in the ash produced by various types of coal combustion, especially in filter cakes from pressurized fluidized bed combustion with dolomite as a SO x sorbent. Previously, qualitative analyses could be performed for Mg 2Ca(SO 4) 3 in these mixtures, but no quantitative analytical method was available. An infrared spectroscopic method has been developed that provides reasonably quantitative results for Mg 2Ca(SO 4) 3, MgSO 4,and CaSO 4 in their mixtures.

  6. Safe and easy method with little modification in technique is useful for successful internal jugular vein cannulation on same side even after intra-arterial puncture without using ultrasound guidance in adult cardiac patients

    PubMed Central

    Thosani, Rajesh; Patel, Jigar; Gandhi, Hemang; Doshi, Chirag; Kothari, Jignesh

    2016-01-01

    Background: The modification in technique is useful for successful right-sided internal jugular vein (IJV) cannulation on the same side even after intra-arterial puncture without using ultrasound guidance in adult patients. Materials and Methods: This study was carried out in total 160 adult patient from American Society of Anesthesiologists Grade II to III patients male (n = 95) and female (n = 65) who underwent cardiac surgery where cannulation was done on right sided by triple lumen catheter (7 French) using Seldinger technique. Results: Majority of patients were cannulated successfully by Seldinger technique with single or double attempt except for five patients in which arterial puncture occurred. All five patients were cannulated successfully on the same side with this modified technique without any significant major complications. They were managed by application of blocker at the end of arterial needle puncture without removing it. In our routine practice, we were used to removing this needle and applying compression for few minutes to prevent hematoma formation after an arterial puncture. In this study, cannula was used as a marker or guideline for the relocation of IJV on the same side and recannulation was performed by changing the direction of needle on same side lateral to the previous one and without going towards the same direction to prevent the arterial puncture again. Conclusion: Most simple and useful modified technique for institutes where the complications are most common with trainee doctors and in hospitals where there is no advanced facility like ultrasound-guided cannulation available. By this modification, it will be time saving, very comfortable, and user-friendly technique with high success rate. PMID:27052069

  7. Ultra-high resolution polarization-sensitive optical coherence microscopy for brain imaging at 6 um, 3.4 um and 1.3 um resolution (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Wang, Hui; Akkin, Taner; Magnain, Caroline V.; Yaseen, Mohammad A.; Cramer, Avilash; Wang, Ruopeng; Sakadžic, Sava; Boas, David A.

    2016-03-01

    Neuroanatomical pathways form the basis for functional activity of brain circuits. In the past, we developed a polarization-sensitive optical coherence tomography with serial scanning to achieve large-scale brain imaging. The system was able to visualize 3D fiber tracts of ~20 um in diameter. To investigate the neuroanatomical pathways at finer scales, we have now built a polarization-maintaining fiber based ultra-high resolution polarization-sensitive optical coherence microscope (PS-OCM) at 1300 nm. The PS-OCM has an axial resolution of 3.5 um in tissue. The detection setup consists of two spectrometers, acquiring spectral interference on orthogonal polarization channels. With a single measurement, the setup generates four contrasts: reflectivity, cross-polarization, retardance and optic axis orientation. To investigate the capability of PS-OCM at different resolutions, we used three microscope objectives that yield lateral resolutions of 6.0 um, 3.4 um and 1.3 um. Blocks of formalin fixed mouse brain and human brain were scanned. The cross-polarization and retardance images clearly depict the neuronal fiber structures, which are comparable with that generated by the maximum projection of volumetric reflectivity data. The optic axis orientation quantifies the in-plane fiber orientation. With the lateral resolution of 1.3 um, the retardance contrast is weak in white matter due to the shallow depth of focus. Overall, the ultra-high resolution PS-OCM provides a new tool to reveal neuroanatomical maps in the brain at cellular resolution.

  8. Thermally stimulated luminescence studies of undoped, Cu- and Mn-doped CaSO4 compounds

    NASA Astrophysics Data System (ADS)

    Manam, J.; Das, S.

    Thermally stimulated luminescence (TSL) of undoped and doped CaSO4 with activators such as Cu and Mn has been investigated. The polycrystalline samples of undoped and doped CaSO4 are prepared by the melting method. The formation of CaSO4 compound is confirmed by X-ray diffraction and Fourier transform infrared studies. Scanning electron microscopic studies of CaSO4 are also carried out. The TSL glow curves of undoped CaSO4, Cu- and Mn-doped CaSO4 are studied. Comparison of the thermoluminescence (TL) intensity of the most intensive glow peak of Cu-doped CaSO4 compound with that of undoped CaSO4 shows that addition of Cu impurity in CaSO4 compound enhances the TL intensity by about four times. However, the addition of Mn impurity to undoped CaSO4 increases the TL intensity by about three times when compared with that of undoped CaSO4. The TL-dose dependence of all three samples was studied and was observed to be almost linear in the studied range of irradiation time. Among the samples studied, namely undoped CaSO4 and Cu- and Mn-doped CaSO4, Cu-doped CaSO4 is found to be the most sensitive. The trap parameters, namely order of kinetics (b), activation energy (E) and frequency factor (s) associated with the most intensive glow peaks of CaSO4:Mn, CaSO4:Cu and CaSO4 phosphors were determined using the glow curve shape (Chen's) method.

  9. QuorUM: An Error Corrector for Illumina Reads

    PubMed Central

    Marçais, Guillaume; Yorke, James A.; Zimin, Aleksey

    2015-01-01

    Motivation Illumina Sequencing data can provide high coverage of a genome by relatively short (most often 100 bp to 150 bp) reads at a low cost. Even with low (advertised 1%) error rate, 100 × coverage Illumina data on average has an error in some read at every base in the genome. These errors make handling the data more complicated because they result in a large number of low-count erroneous k-mers in the reads. However, there is enough information in the reads to correct most of the sequencing errors, thus making subsequent use of the data (e.g. for mapping or assembly) easier. Here we use the term “error correction” to denote the reduction in errors due to both changes in individual bases and trimming of unusable sequence. We developed an error correction software called QuorUM. QuorUM is mainly aimed at error correcting Illumina reads for subsequent assembly. It is designed around the novel idea of minimizing the number of distinct erroneous k-mers in the output reads and preserving the most true k-mers, and we introduce a composite statistic π that measures how successful we are at achieving this dual goal. We evaluate the performance of QuorUM by correcting actual Illumina reads from genomes for which a reference assembly is available. Results We produce trimmed and error-corrected reads that result in assemblies with longer contigs and fewer errors. We compared QuorUM against several published error correctors and found that it is the best performer in most metrics we use. QuorUM is efficiently implemented making use of current multi-core computing architectures and it is suitable for large data sets (1 billion bases checked and corrected per day per core). We also demonstrate that a third-party assembler (SOAPdenovo) benefits significantly from using QuorUM error-corrected reads. QuorUM error corrected reads result in a factor of 1.1 to 4 improvement in N50 contig size compared to using the original reads with SOAPdenovo for the data sets investigated

  10. Universal Monitor (UM) for OTEC compact heat exchangers

    SciTech Connect

    Kuzay, T.M.

    1981-09-01

    Universal Monitor (UM), is a device-independent concept to measure, with precision, the initiation and progression of fouling in any given OTEC Compact Heat Exchanger model with or without the application of countermeasures. Design description and supporting analyses for the Universal Monitor for OTEC Compact Heat Exchangers are presented.

  11. The International Space Station Urine Monitoring System (UMS)

    NASA Technical Reports Server (NTRS)

    Feeback, Daniel L.; Cibuzar, Branelle R.; Milstead, Jeffery R.; Pietrzyk,, Robert A.; Clark, Mark S.F.

    2009-01-01

    A device capable of making in-flight volume measurements of single void urine samples, the Urine Monitoring System (UMS), was developed and flown on seven U.S. Space Shuttle missions. This device provided volume data for each urine void from multiple crewmembers and allowed samples of each to be taken and returned to Earth for post-flight analysis. There were a number of design flaws in the original instrument including the presence of liquid carry-over producing invalid "actual" micturition volumes and cross-contamination between successive users from residual urine in "dead" spots". Additionally, high or low volume voids could not be accurately measured, the on-orbit calibration and nominal use sequence was time intensive, and the unit had to be returned and disassembled to retrieve the volume data. These problems have been resolved in a new version, the International Space Station (ISS) UMS, that has been designed to provide real-time in-flight volume data with accuracy and precision equivalent to measurements made on Earth and the ability to provide urine samples that are unadulterated by the device. Originally conceived to be interfaced with a U.S.-built Waste Collection System (WCS), the unit now has been modified to interface with the Russian-supplied Sanitary Hygiene Device (ASY). The ISS UMS provides significant advantages over the current method of collecting urine samples into Urine Collection Devices (UCDs), from which samples are removed and returned to Earth for analyses. A significant future advantage of the UMS is that it can provide an interface to analytical instrumentation that will allow real-time measurement of urine bioanalytes allowing monitoring of crewmember health status during flight and the ability to provide medical interventions based on the results of these measurements. Currently, the ISS UMS is scheduled to launch along with Node-3 on STS-130 (20A) in December 2009. UMS will be installed and scientific/functional verification

  12. Genome analysis of Daldinia eschscholtzii strains UM 1400 and UM 1020, wood-decaying fungi isolated from human hosts

    SciTech Connect

    Chan, Chai Ling; Yew, Su Mei; Ngeow, Yun Fong; Na, Shiang Ling; Lee, Kok Wei; Hoh, Chee-Choong; Yee, Wai-Yan; Ng, Kee Peng

    2015-11-18

    Background: Daldinia eschscholtzii is a wood-inhabiting fungus that causes wood decay under certain conditions. It has a broad host range and produces a large repertoire of potentially bioactive compounds. However, there is no extensive genome analysis on this fungal species. Results: Two fungal isolates (UM 1400 and UM 1020) from human specimens were identified as Daldinia eschscholtzii by morphological features and ITS-based phylogenetic analysis. Both genomes were similar in size with 10,822 predicted genes in UM 1400 (35.8 Mb) and 11,120 predicted genes in UM 1020 (35.5 Mb). A total of 751 gene families were shared among both UM isolates, including gene families associated with fungus-host interactions. In the CAZyme comparative analysis, both genomes were found to contain arrays of CAZyme related to plant cell wall degradation. Genes encoding secreted peptidases were found in the genomes, which encode for the peptidases involved in the degradation of structural proteins in plant cell wall. In addition, arrays of secondary metabolite backbone genes were identified in both genomes, indicating of their potential to produce bioactive secondary metabolites. Both genomes also contained an abundance of gene encoding signaling components, with three proposed MAPK cascades involved in cell wall integrity, osmoregulation, and mating/filamentation. Besides genomic evidence for degrading capability, both isolates also harbored an array of genes encoding stress response proteins that are potentially significant for adaptation to living in the hostile environments. In conclusion: Our genomic studies provide further information for the biological understanding of the D. eschscholtzii and suggest that these wood-decaying fungi are also equipped for adaptation to adverse environments in the human host.

  13. Genome analysis of Daldinia eschscholtzii strains UM 1400 and UM 1020, wood-decaying fungi isolated from human hosts

    DOE PAGES

    Chan, Chai Ling; Yew, Su Mei; Ngeow, Yun Fong; ...

    2015-11-18

    Background: Daldinia eschscholtzii is a wood-inhabiting fungus that causes wood decay under certain conditions. It has a broad host range and produces a large repertoire of potentially bioactive compounds. However, there is no extensive genome analysis on this fungal species. Results: Two fungal isolates (UM 1400 and UM 1020) from human specimens were identified as Daldinia eschscholtzii by morphological features and ITS-based phylogenetic analysis. Both genomes were similar in size with 10,822 predicted genes in UM 1400 (35.8 Mb) and 11,120 predicted genes in UM 1020 (35.5 Mb). A total of 751 gene families were shared among both UM isolates,more » including gene families associated with fungus-host interactions. In the CAZyme comparative analysis, both genomes were found to contain arrays of CAZyme related to plant cell wall degradation. Genes encoding secreted peptidases were found in the genomes, which encode for the peptidases involved in the degradation of structural proteins in plant cell wall. In addition, arrays of secondary metabolite backbone genes were identified in both genomes, indicating of their potential to produce bioactive secondary metabolites. Both genomes also contained an abundance of gene encoding signaling components, with three proposed MAPK cascades involved in cell wall integrity, osmoregulation, and mating/filamentation. Besides genomic evidence for degrading capability, both isolates also harbored an array of genes encoding stress response proteins that are potentially significant for adaptation to living in the hostile environments. In conclusion: Our genomic studies provide further information for the biological understanding of the D. eschscholtzii and suggest that these wood-decaying fungi are also equipped for adaptation to adverse environments in the human host.« less

  14. Recombination luminescence of CaSO4:Tb3+ and CaSO4:Gd3+phosphors

    NASA Astrophysics Data System (ADS)

    Kudryavtseva, Irina; Lushchik, Aleksandr; Maaroos, Aarne; Azmaganbetova, Zhannur; Nurakhmetov, Turlybek; Salikhoja, Zhussupbek

    2012-08-01

    A comparative study of the excitation of luminescence by VUV radiation as well as of thermally and photostimulated luminescence has been carried out for CaSO4:Tb3+ and CaSO4:Gd3+ phosphors, where Na+ or F- ions are used for charge compensation. The distinction in hole processes for the phosphors with Na+ or F- compensators is determined by the differing thermal stability of the holes localized at/near Tb3+Na+ and Gd3+Na+ (up to 100-160 K) or at/near Tb3+F- V Ca and Gd3+F- V Ca centers involving also a cation vacancy (up to 400-550 K). Tunnel luminescence in the pairs of localized electrons and holes nearby Tb3+ or Gd3+ has been detected. The mechanisms of electron-hole, hole-electron and tunnel recombination luminescence as well as a subsequent released energy transfer to RE3+ ions are considered.

  15. STS-40 Exp. No. 192 urine monitoring system (UMS) on OV-102's middeck

    NASA Technical Reports Server (NTRS)

    1991-01-01

    STS-40 Experiment No. 192, Fluid-Electrolyte Regulation During Space Flight, urine monitoring system (UMS) is set up on the middeck of Columbia, Orbiter Vehicle (OV) 102, at the side hatch. The UMS is attached to OV-102's waste collection system (WCS). The urine specimen tray with sample tubes appears to the right of the UMS equipment.

  16. The binary system K2SO4CaSO4

    USGS Publications Warehouse

    Rowe, J.J.; Morey, G.W.; Hansen, I.D.

    1965-01-01

    The binary system K2SO4CaSO4 was studied by means of heating-cooling curves, differential thermal analysis, high-temperature quenching technique and by means of a heating stage mounted on an X-ray diffractometer. Compositions and quench products were identified optically and by X-ray. Limited solid solution of CaSO4 in K2SO4 was found. There is a eutectic at 875??C and 34 wt. per cent CaSO4. Calcium langbeinite melts incongruently at 1011??C. The melting-point of CaSO4 (1462??C) was determined by the quenching technique using sealed platinum tubes. The only intermediate crystalline phase found in the system is K2SO4??2CaSO4 (calcium langbeinite). ?? 1965.

  17. ESR and TL mechanism in CaSO4 : Ag co-doped phosphors

    NASA Astrophysics Data System (ADS)

    Dhabekar, Bhushan; Menon, Sanjeev; Alagu Raja, E.; Sanaye, S. S.; Gundu Rao, T. K.; Bhatt, B. C.; Kher, R. K.

    2006-06-01

    Thermoluminescence (TL) studies have been carried out on CaSO4 : Mn, CaSO4 : Ag,Mn, CaSO4 : Ag,Nd, CaSO4 : Ag,Mn,Nd, CaSO4 : Ag,Zr and CaSO4 : Ag,Mn,Zr phosphors. It is found that TL at 360 °C in CaSO4 : Ag,Mn,Nd is about 40 times that of CaSO4 : Ag,Mn and about 170 times that of CaSO4 : Ag,Nd. This shows that the presence of an efficient luminescent centre (Mn2+) as well as a trivalent impurity (such as Nd3+ or Y3+) is important for enhancement of TL at 360 °C in the CaSO4 : Ag,Mn,Nd phosphor system. Electron spin resonance (ESR) studies show that the peak at 360 °C correlates with an Ag2+ centre formed due to γ-irradiation and observable only below -170 °C. The Ag2+ centre is characterized by an axial g-tensor with principal values g|| = 2.38 and gbottom = 2.41. ESR studies further indicate that the precursor to a centre observable at low temperature (-170 °C) appears to act as the recombination centre for the TL peak at 360 °C. The low temperature centre is characterized by the g-values g|| = 2.0023 and gbottom = 2.0038 and is assigned to the SO_{3}^{ - } radical.

  18. STAR CLUSTER COMPLEXES AND THE HOST GALAXY IN THREE H II GALAXIES: Mrk 36, UM 408, AND UM 461

    SciTech Connect

    Lagos, P.; Telles, E.; Nigoche-Netro, A.

    2011-11-15

    We present a stellar population study of three H II galaxies (Mrk 36, UM 408, and UM 461) based on the analysis of new ground-based high-resolution near-infrared J, H, and K{sub p} broadband and Br{gamma} narrowband images obtained with Gemini/NIRI. We identify and determine the relative ages and masses of the elementary star clusters and/or star cluster complexes of the starburst regions in each of these galaxies by comparing the colors with evolutionary synthesis models that include the contribution of stellar continuum, nebular continuum, and emission lines. We found that the current star cluster formation efficiency in our sample of low-luminosity H II galaxies is {approx}10%. Therefore, most of the recent star formation is not in massive clusters. Our findings seem to indicate that the star formation mode in our sample of galaxies is clumpy, and that these complexes are formed by a few massive star clusters with masses {approx}>10{sup 4} M{sub Sun }. The age distribution of these star cluster complexes shows that the current burst started recently and likely simultaneously over short timescales in their host galaxies, triggered by some internal mechanism. Finally, the fraction of the total cluster mass with respect to the low surface brightness (or host galaxy) mass, considering our complete range in ages, is less than 1%.

  19. The ternary system K2SO4MgSO4CaSO4

    USGS Publications Warehouse

    Rowe, J.J.; Morey, G.W.; Silber, C.C.

    1967-01-01

    Melting and subsolidus relations in the system K2SO4MgSO4CaSO4 were studied using heating-cooling curves, differential thermal analysis, optics, X-ray diffraction at room and high temperatures and by quenching techniques. Previous investigators were unable to study the binary MgSO4CaSO4 system and the adjacent area in the ternary system because of the decomposition of MgSO4 and CaSO4 at high temperatures. This problem was partly overcome by a novel sealed-tube quenching method, by hydrothermal synthesis, and by long-time heating in the solidus. As a result of this study, we found: (1) a new compound, CaSO4??3MgSO4 (m.p. 1201??C) with a field extending into the ternary system; (2) a high temperature form of MgSO4 with a sluggishly reversible inversion. An X-ray diffraction pattern for this polymorphic form is given; (3) the inversion of ??-CaSO4 (anhydrite) to ??-CaSO4 at 1195??C, in agreement with grahmann; (1) (4) the melting point of MgSO4 is 1136??C and that of CaSO4 is 1462??C (using sealed tube methods to prevent decomposition of the sulphates); (5) calcium langbeinite (K2SO4??2CaSO4) is the only compound in the K2SO4CaSO4 binary system. This resolved discrepancies in the results of previous investigators; (6) a continuous solid solution series between congruently melting K2SOP4??2MgSO4 (langbeinite) and incongruently melting K2SO4??2CaSO4 (calcium langbeinite); (7) the liquidus in the ternary system consists of primary phase fields of K2SO4, MgSO4, CaSO4, langbeinite-calcium langbeinite solid solution, and CaSO4??3MgSO4. The CaSO4 field extends over a large portion of the system. Previously reported fields for the compounds (K2SO4??MgSO4??nCaSO4), K2SO4??3CaSO4 and K2SO4??CaSO4 were not found; (8) a minimum in the ternary system at: 740??C, 25% MgSO4, 6% CaSO4, 69% K2SO4; and ternary eutectics at 882??C, 49% MgSO4, 19% CaSO4, 32% K2SO4; and 880??, 67??5% MgSO4, 5% CaSO4, 27??5% K2SO4. ?? 1967.

  20. Recovery Act: Novel Kerf-Free PV Wafering that provides a low-cost approach to generate wafers from 150um to 50um in thickness

    SciTech Connect

    Fong, Theodore E.

    2013-05-06

    The technical paper summarizes the project work conducted in the development of Kerf-Free silicon wafering equipment for silicon solar wafering. This new PolyMax technology uses a two step process of implantation and cleaving to exfoliate 50um to 120um wafers with thicknesses ranging from 50um to 120um from a 125mm or 156mm pseudo-squared silicon ingot. No kerf is generated using this method of wafering. This method of wafering contrasts with the current method of making silicon solar wafers using the industry standard wire saw equipment. The report summarizes the activity conducted by Silicon Genesis Corporation in working to develop this technology further and to define the roadmap specifications for the first commercial proto-type equipment for high volume solar wafer manufacturing using the PolyMax technology.

  1. Unit 5, STA. 50+00+RB, Orner Building, First U.M. Church Rectory, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Unit 5, STA. 50+00+RB, Orner Building, First U.M. Church Rectory, & First U.M. Church-context - Johnstown Local Flood Protection Project, Beginning on Conemaugh River approx 3.8 miles downstream from confluence of Little Conemaugh & Stony Creek Rivers at Johnstown, Johnstown, Cambria County, PA

  2. Report to the Maryland General Assembly on UMS Institutional and System Identities.

    ERIC Educational Resources Information Center

    Maryland Univ. System Administration, Adelphi.

    This report examines the use of the name "University of Maryland System" (UMS) to characterize the state's university system and its 13 institutions. It is noted that the UMS name is somewhat misleading, in that it suggests that the system comprises only the seven institutions with "University of Maryland" in their name. The…

  3. Adults Return to Mathematics: A Proposed Project in Uganda by the Uganda Mathematical Society (UMS).

    ERIC Educational Resources Information Center

    Kaahwa, Janet

    This paper provides information on a project by the Uganda Mathematical Society (UMS) that aims to popularize mathematics in Uganda. UMS believes that if parents learn mathematics (primary and secondary), they will be able to help their children themselves instead of hiring others to coach their children as is the practice today. Another way to…

  4. HD 208905: um sistema múltiplo de estrelas quentes

    NASA Astrophysics Data System (ADS)

    Candeias, J. P.; Daflon, S.; Cunha, K.

    2003-08-01

    Durante o survey de associações OB do disco Galáctico, foi constatada a multiplicidade do sistema HD 208905, pertencentes à associação de Cep OB2. Este objeto está classificado como uma estrela pertencente a um sistema múltiplo, com magnitude mv = 7.0 e tipo espectral B1V. De fato, os espectros de HD 208905 apresentam perfis de absorção triplicados. Dois dos perfis são bastante similares entre si, e são estreitos e bem definidos, sugerindo que as velocidades rotacionais projetadas (v sin i) das duas estrelas são baixas. Os espectros obtidos também apresentam perfis mais alargados que poderiam ser atribuídos a uma terceira componente estelar com v sin i mais alto. A análise de HD 208905 é baseada no estudo da variação da posição relativa dos perfis espectrais de acordo com a fase do sistema. Nossos dados observacionais são um conjunto de espectros de alta resolução obtidos no McDonald Observatory (Universidade do Texas, Austin), Kitt Peak National Observatory e Palomar Observatory, cobrindo o período de 10/91 até 12/95. Inicialmente, calculamos a velocidade radial de cada componente do sistema, considerando o desvio Doppler sofrido por cada estrela. As velocidades radiais medidas foram, em seguida, corrigidas para velocidades radiais heliocêntricas. O passo seguinte constituiu na determinação da periodicidade da série temporal definida pelas medidas das velocidades radiais heliocêntricas através da análise de Fourier. A nossa base de dados não permitiu definir uma solução única para o sistema HD 208905. As possíveis soluções encontradas têm períodos entre 1 e 27 dias e serão apresentadas e discutidas.

  5. Time Variable Associated Absorption in the QSO UM 675

    NASA Astrophysics Data System (ADS)

    Hamann, F. W.; Barlow, T. A.; Beaver, E. A.; Burbidge, E. M.; Cohen, R. D.; Junkkarinen, V. T.; Lyons, R. W.

    1994-05-01

    We discuss dramatic changes in the z_a ~ z_e absorption system of the z_e = 2.15 QSO UM 675 (Q0150-203). The C IV lambda 1550 and N V lambda 1240 doublets at z_a = 2.1344 strengthened by a factor of ~ 3 between the observations of Sargent, Boksenberg and Steidel (1988, ApJS, 68, 539; measured November 1981) and our earliest measurements (November and December 1990). During this time, C IV in the z_a = 2.0083 system may also have strengthened. The variability of other lines in these systems is unknown. Continued monitoring is in progress. We consider several models of the z_a ~ z_e absorption environment, and conclude that the absorbing clouds are close to the QSO and photoionized by the QSO continuum. The variability timescale (<~2.9 yrs rest) requires gas densities gap 4000 cm(-3) to allow changes in the ionization balance. This minimum density, and the high ionization needed to produce the Ne VIII lambda 774 and O VI lambda 1035 absorptions reported previously (E. M. Burbidge et al., 1993, BAAS, 24, 1135), requires clouds <~200 pc from the QSO. The full range of absorption line ionizations (including C III lambda 977 and N III lambda 989) implies that the clouds are segregated, spanning a factor of gap 10 in distance or gap 100 in density. Across these regions the H I fraction varies from ~ 10(-3) to ~ 10(-6) . The total hydrogen column ranges from a few times 10(18) cm(-2) in the low ionization gas to ~ 10(20) cm(-2) where the Ne VIII lines form. The Lyman continuum is expected to be optically thin throughout, consistent with the measured absence of a Lyman edge. The metal abundances are roughly solar or above. Implications of these results are discussed. This work is supported by NASA grant NAG 5-1630.

  6. VizieR Online Data Catalog: Draco nebula Herschel 250um map (Miville-Deschenes+, 2017)

    NASA Astrophysics Data System (ADS)

    Miville-Deschenes, M.-A.; Salome, Q.; Martin, P. G.; Joncas, G.; Blagrave, K.; Dassas, K.; Abergel, A.; Beelen, A.; Boulanger, F.; Lagache, G.; Lockman, F. J.; Marshall, D. J.

    2017-03-01

    Draco was observed with Herschel PACS (110 and 170um) and SPIRE (250, 350 and 500um) as part of the open-time program "First steps toward star formation: unveiling the atomic to molecular transition in the diffuse interstellar medium" (P.I. M-A Miville-Deschenes). A field of 3.85x3.85 was observed in parallel mode. Unfortunately, an error occurred during the acquisition of the PACS data making them unusable. Therefore, the results presented here are solely based on SPIRE data, especially the 250um map that has the highest angular resolution. (2 data files).

  7. Feasibility study of CaSO4:Tb,Yb as a thermoluminescent dosimeter

    NASA Astrophysics Data System (ADS)

    Junot, Danilo O.; Santos, Max A.; Chagas, Marcos A. P.; Couto dos Santos, Marcos A.; Nunes, Luiz A. O.; Souza, Divanizia N.

    2014-02-01

    A new composite based on CaSO4, using terbium as dopant and ytterbium as co-dopant (CaSO4:Tb,Yb), was developed for employment as a thermoluminescent (TL) dosimeter. The crystals used in this work were grown using a production route based on the Yamashita method (Yamashita et al., 1968). Crystal powder was calcined at 600 °C for 1 h. Pellets were made by adding commercial and colorless glass to improve physical resistance and sintered at 700 °C for 6 h. All samples were irradiated by a beta source (90Sr/90Y) and received doses from 1 Gy to 5 Gy. TL analyses have been performed and characteristics such as sensitivity, reproducibility, linearity, and fading have been studied. The CaSO4:Tb,Yb pellets glow curves presented two peaks, the first at around 115 °C, and the second at around 200 °C. The highest intensity was shown for CaSO4:Tb,Yb with a concentration of 0.1 mol% of Tb and Yb together. In all the samples the TL response was proportional to the absorbed dose. Therefore, the CaSO4:Tb,Yb has potential to be used as a thermoluminescent dosimeter.

  8. Reduction Kinetics of a CasO4 Based Oxygen Carrier for Chemical-Looping Combustion

    NASA Astrophysics Data System (ADS)

    Xiao, R.; Song, Q. L.; Zheng, W. G.; Deng, Z. Y.; Shen, L. H.; Zhang, M. Y.

    The CaSO4 based oxygen carrier has been proposed as an alternative low cost oxygen carrier for Chemical-looping combustion (CLC) of coal. The reduction of CaSO4 to CaS is an important step for the cyclic process of reduction/oxidation in CLC of coal with CaSO4 based oxygen carrier. Thermodynamic analysis of CaSO4 oxygen carrier with CO based on the principle of Gibbs free energy minimization show that the essentially high purity of CO2 can be obtained, while the solid product is CaS instead of CaO. The intrinsic reduction kinetics of a CaSO4 based oxygen carrier with CO was investigated in a differential fixed bed reactor. The effects of gas partial pressure (20%-70%) and temperature (880-950°C) on the reduction were investigated. The reduction was described with shrinking unreacted core model. Experimental results of CO partial pressure on the solid conversion show that the reduction of fresh oxygen carriers is of first order with respect to the CO partial pressure. Both chemical reaction control and product layer diffusion control determine the reduction rate. The dependences of reaction rate constant and effective diffusivity with temperature were both obtained. The kinetic equation well predicted the experimental data.

  9. Ground-based observation of the Venus 1.27-um O2 airglow

    NASA Astrophysics Data System (ADS)

    Ohtsuki, S.; Iwagami, N.; Sagawa, H.; Kasaba, Y.; Ueno, M.; Imamura, T.

    We conducted near-infrared imaging spectroscopy of the nightside of Venus at Okayama Astrophysical Observatory Japan on December 11, 2002. The 1.3-um spectra show 1.27-um O_2 IRA (0,0) airglow feature and thermal emission from the lower atmosphere. The brightest airglow feature of 5MR is found at the anti-solar point, which agrees with the previous studies. The hemispheric distribution of 1.3-um thermal emission shows equatorial depression similar to that of the 2-um region in previous studies. The hemispheric distribution of the rotational temperature shows a hot region at around the anti-solar point overlapping the bright region, and which suggests adiabatic heating due to the downward flow.

  10. UM206, a selective Frizzled antagonist, attenuates adverse remodeling after myocardial infarction in swine.

    PubMed

    Uitterdijk, André; Hermans, Kevin C M; de Wijs-Meijler, Daphne P M; Daskalopoulos, Evangelos P; Reiss, Irwin K; Duncker, Dirk J; Matthijs Blankesteijn, W; Merkus, Daphne

    2016-02-01

    Modulation of Wnt/Frizzled signaling with UM206 reduced infarct expansion and prevented heart failure development in mice, an effect that was accompanied by increased myofibroblast presence in the infarct, suggesting that Wnt/Frizzled signaling has a key role in cardiac remodeling following myocardial infarction (MI). This study investigated the effects of modulation of Wnt/Frizzled signaling with UM206 in a swine model of reperfused MI. For this purpose, seven swine with MI were treated with continuous infusion of UM206 for 5 weeks. Six control swine were treated with vehicle. Another eight swine were sham-operated. Cardiac function was determined by echo in awake swine. Infarct mass was estimated at baseline by heart-specific fatty acid-binding protein ELISA and at follow-up using planimetry. Components of Wnt/Frizzled signaling, myofibroblast presence, and extracellular matrix were measured at follow-up with qPCR and/or histology. Results show that UM206 treatment resulted in a significant decrease in infarct mass compared with baseline (-41±10%), whereas infarct mass remained stable in the Control-MI group (+3±17%). Progressive dilation of the left ventricle occurred in the Control-MI group between 3 and 5 weeks after MI, while adverse remodeling was halted in the UM206-treated group. mRNA expression for Frizzled-4 and the Frizzled co-receptor LRP5 was increased in UM206-treated swine as compared with Control-MI swine. Myofibroblast presence was significantly lower in infarcted tissue of the UM206-treated animals (1.53±0.43% vs 3.38±0.61%) at 5 weeks follow-up. This study demonstrates that UM206 treatment attenuates adverse remodeling in a swine model of reperfused MI, indicating that Wnt/Frizzled signaling is a promising target to improve infarct healing and limit post-MI remodeling.

  11. 31.5um imaging observations of AGN using SOFIA/FORCAST

    NASA Astrophysics Data System (ADS)

    Fuller, Lindsay; Lopez-Rodriguez, Enrique; Packham, Christopher C.; Los Piratas Team

    2016-01-01

    The unified model of active galactic nuclei (AGN) requires a toroidal region of optically and geometrically thick dust obscuring a central engine, accounting for various observed spectral features. Our aim is to investigate the overall torus properties to obtain analytical results for its physical parameters. We present 31.5um photometric observations of 12 nearby Seyfert galaxies from the 2.5m SOFIA telescope using the FORCAST camera. We used Clumpy torus models and a Bayesian approach to fit the IR (1.2-31.5um) nuclear SEDs and high angular resolution mid-IR (8-13um) spectroscopy. We found that the turnover of the torus emission does not occur at wavelengths <31.5um, which we interpret as a lower-limit for the peak torus emission. Including the 31.5um nuclear flux 1) reduces the dispersion of Clumpy torus models at wavelengths >30um, which better constrains the model parameters, 2) generally decreases the radial extent of the torus. We find torus radii ranging from ~1 - 8.5pc, with an average radius of 2.6pc, which is consistent with interferometric and high-spatial resolution observations.

  12. Spectroscopy of JVI Himalia for detection and characterization of the 3 um water band

    NASA Astrophysics Data System (ADS)

    Schindler, Karsten

    2013-10-01

    We aim at securely detecting and characterizing the presence of the 3um band for the first time in the reflectance spectrum of a Jovian irregular satellite. Features in the 3um band can unambiguously reveal water ice or past aqueous alteration of the surface material that lead to bound water molecules and hydroxyl groups in minerals. Water ice and hydrated minerals are ubiquitous in the Jovian system and have been found on Europa, Ganymede, Callisto and the inner regular satellite JV Amalthea. In contrast to these neighboring satellites and to two irregular satellites that have been studied at Saturn and Neptune, a detection of water (previously or currently present) on a Jovian irregular satellite has not yet been succeeded due to constraints of ground-based observatories. No dedicated spacecraft mission to the Jovian system has allowed to study them close-up. Their very low albedos and small diameters only allow ground-based spectroscopy up to 2.5um for very few objects. The strong telluric absorption band of the atmosphere between 2.55-2.85um and the increasing IR-background beyond 2.85um makes ground-based spectroscopy for these very faint objects impossible. SOFIA has the unique capability to overcome these limits. Flitecam provides enough sensitivity to conduct spectroscopic investigations between 2.6-3.5um of the largest object of the Jovian irregular satellite population, JVI Himalia. Supplementary high quality spectral data from 0.65-2.55um has already been acquired by Schindler and Reddy using SpeX on NASA IRTF. Three indicators strongly suggest the presence of the 3um band: A shallow absorption feature around 1.1um attributed to magnetite, a weak feature around 0.7 um attributed to phyllosillicates and an average heliocentric distance of 5.2AU where water ice is thought to be stable throughout the history of the Solar System. The results of this study will greatly contribute to understand the origin and history of these objects.

  13. Impulsive excitation of mechanoluminescence in gamma-irradiated CaSO4:Eu phosphors

    NASA Astrophysics Data System (ADS)

    Kher, R. S.; Dhoble, S. J.; Pandey, R. K.; Upadhyay, A. K.; Khokhar, M. S. K.

    2011-01-01

    The mechanoluminescence (ML) and thermoluminescence (TL) of γ-irradiated CaSO4:Eu phosphor have been studied. CaSO4 samples having different concentrations of Eu were prepared by dissolving CaSO4.2H2O in sulphuric acid and evaporating the excess acid around 300 °C. ML was excited impulsively by dropping a load onto the sample. Three distinct peaks have been observed in the ML intensity versus time curve. The ML intensity increases with the increasing concentration of the dopant. The effect of temperature on the shape and peak of ML intensity was also recorded. Growth, saturation and broadening in an ML peak were observed. TL glow curves of CaSO4:Eu phosphors at different concentrations contain two TL peaks: the first peak was observed at around 110 °C and the other at 210 °C. Experimental results suggest that the ML excitation is related to the movement of dislocation with defect centres, the increase in ML with temperature is due to the enhancement in dislocation capture probability, and the reduction is due to the thermal bleaching of defect centres.

  14. UM-PRS: An implementation of the procedural reasoning system for multirobot applications

    NASA Technical Reports Server (NTRS)

    Lee, Jaeho; Huber, Marcus J.; Durfee, Edmund H.; Kenny, Patrick G.

    1994-01-01

    The Procedural Reasoning System (PRS) is used in applications where predetermined situations might arise. The UM-PRS provides a reasoning system that represents robotic applications even in unpredictable domains, such as the robotic reconnaissance task domain outlined here. UM-PRS incorporates a changing context, rather than relying solely on a prearranged plan. The UM-PRS here provides representation important in the reasoning and interface between a mission plan and the executable map of an outdoor vehicle that changes its behavior based on what it comes in contact with in its environment. PRS is thus used in the dynamic control of such a vehicle, providing the basis for coordinating the joint task of multiple robotic vehicles by the their individual observations and representation.

  15. Protective Effects of Ultramicronized Palmitoylethanolamide (PEA-um) in Myocardial Ischaemia and Reperfusion Injury in VIVO.

    PubMed

    Di Paola, Rosanna; Cordaro, Marika; Crupi, Rosalia; Siracusa, Rosalba; Campolo, Michela; Bruschetta, Giuseppe; Fusco, Roberta; Pugliatti, Pietro; Esposito, Emanuela; Cuzzocrea, Salvatore

    2016-08-01

    Myocardial infarction is the leading cause of death, occurs after prolonged ischemia of the coronary arteries. Restore blood flow is the first intervention help against heart attack. However, reperfusion of the arteries leads to ischemia/reperfusion injury (I/R). The fatty acid amide palmitoylethanolamide (PEA) is an endogenous compound widely present in living organisms, with analgesic and anti-inflammatory properties. The present study evaluated the effect of ultramicronized palmitoylethanolamide (PEA-um) treatment on the inflammatory process associated with myocardial I/R. Myocardial ischemia reperfusion injury was induced by occlusion of the left anterior descending coronary artery for 30 min followed by 2 h of reperfusion. PEA-um, was administered (10 mg/kg) 15 min after ischemia and 1 h after reperfusion. In this study, we demonstrated that PEA-um treatment reduces myocardial tissue injury, neutrophil infiltration, adhesion molecules (ICAM-1, P-selectin) expression, proinflammatory cytokines (TNF-α, IL-1β) production, nitrotyrosine and PAR formation, nuclear factor kB expression, and apoptosis (Fas-L, Bcl-2) activation. In addition to study whether the protective effect of PEA-um on myocardial ischemia reperfusion injury is also related to the activation of PPAR-α, in a separate set of experiments it has been performed myocardial I/R in PPARα mice. Genetic ablation of peroxisome proliferator activated receptor (PPAR)-α in PPAR-αKO mice exacerbated Myocardial ischemia reperfusion injury when compared with PPAR-αWT mice. PEA-um induced cardioprotection in PPAR-α wild-type mice, but the same effect cannot be observed in PPAR-αKO mice. Our results have clearly shown a modulation of the inflammatory process, associated with myocardial ischemia reperfusion injury, following administration of PEA-um.

  16. Vínculos sobre um modelo de quartessência de Chaplygin usando observações do satélite chandra da fração de massa de gás em aglomerados de galáxias

    NASA Astrophysics Data System (ADS)

    de Souza, R. S.

    2003-08-01

    Observações de Supernovas do tipo Ia mostram que a expansão do Universo está acelerando. Segundo as equações de Einstein uma componente com pressão negativa (energia escura) é necessária para explicar a aceleração cósmica. Além da energia escura é usualmente admitido que no Universo há também uma matéria exótica com pressão zero, que é chamada de matéria escura. Essa componente possui um papel fundamental na formação de estruturas no Universo. Recentemente tem se explorado a possibilidade de que matéria e energia escura poderiam ser unificadas através de uma única componente, que tem sido denominada de quartessência. Um exemplo de fluido com essas características é o Gás de Chaplygin Generalizado, que possui uma equação de estado da forma p = -A/ra. Inicialmente consideramos o caso especial a = 1 (gás de Chaplygin) e vinculamos parâmetros do modelo utilizando observações em raios-X do satélite Chandra da fração de massa de gás em aglomerados de galáxias. Uma comparação dos vínculos obtidos com esse teste com outros testes, tais como supernovas e idade do Universo, mostra que esse teste é bastante restritivo. Exibiremos ainda resultados para o caso em que a curvatura é nula e o parâmetro a está compreendido no intervalo -1 < a 1.

  17. Unit 5, STA. 50+00+RB, retaining wall at First U.M. Churchdetail ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Unit 5, STA. 50+00+RB, retaining wall at First U.M. Church-detail - Johnstown Local Flood Protection Project, Beginning on Conemaugh River approx 3.8 miles downstream from confluence of Little Conemaugh & Stony Creek Rivers at Johnstown, Johnstown, Cambria County, PA

  18. Use of "um" in the Deceptive Speech of a Convicted Murderer

    ERIC Educational Resources Information Center

    Villar, Gina; Arciuli, Joanne; Mallard, David

    2012-01-01

    Previous studies have demonstrated a link between language behaviors and deception; however, questions remain about the role of specific linguistic cues, especially in real-life high-stakes lies. This study investigated use of the so-called filler, "um," in externally verifiable truthful versus deceptive speech of a convicted murderer. The data…

  19. Evolution and Persistence of 5-um Hot Spots at the Galileo Probe entry Latitude

    NASA Technical Reports Server (NTRS)

    Fisher, B. M.

    1997-01-01

    We present a study on the longtudinal locations, morphology and evolution of the 5-um hot spots at 6.5 deg. N latitude (planetocentric), from an extensive IRTF-NSFCAM data set spanning more that 3 years, which includes the date of the Galileo Probe entry.

  20. Draft Genome Sequence of Ochroconis constricta UM 578, Isolated from Human Skin Scraping.

    PubMed

    Chan, Chai Ling; Yew, Su Mei; Na, Shiang Ling; Tan, Yung-Chie; Lee, Kok Wei; Yee, Wai-Yan; Ngeow, Yun Fong; Ng, Kee Peng

    2014-04-17

    Ochroconis constricta is a soilborne dematiaceous fungus that has never been reported to be associated with human infection. Here we report the first draft genome sequence of strain UM 578, isolated from human skin scraping. The genomic information revealed will contribute to a better understanding of this species.

  1. Variabilidade óptica de longo período e precessão de jato: o caso de BL Lacertae

    NASA Astrophysics Data System (ADS)

    Caproni, A.; Abraham, Z.

    2003-08-01

    Variabilidade é tipicamente uma característica de AGNs, sendo observada em toda a faixa eletromagnética. Em relação às escalas de tempo, variações desde horas até de algumas décadas foram encontradas por vários autores. Em alguns casos, análises temporais de curvas de luz mostram a existência de periodicidade nas variações observadas. Um exemplo de objeto que preenche as características mencionadas acima é BL Lacertae, o protótipo da classe BL Lac dos AGNs. Neste trabalho, nós interpretamos a variabilidade periódica de longo período detectada na curva de luz na banda B (~7,5 anos) como o resultado da periodicidade na amplificação da radiação oriunda do jato relativístico. Neste cenário, a amplificação periódica seria induzida pela precessão, que muda o ângulo entre o jato e a linha de visada. Com esta abordagem e vínculos adicionais fornecidos por observações em altas energias, nós podemos impor limites para os parâmetros do modelo de precessão, tais como o fator de Lorentz associado ao movimento global do jato, o ângulo de abertura do cone de precessão e o ângulo entre o eixo do cone e a linha de visada.

  2. Ultramicronized palmitoylethanolamide (PEA-um(®)) in the treatment of idiopathic pulmonary fibrosis.

    PubMed

    Di Paola, Rosanna; Impellizzeri, Daniela; Fusco, Roberta; Cordaro, Marika; Siracusa, Rosalba; Crupi, Rosalia; Esposito, Emanuela; Cuzzocrea, Salvatore

    2016-09-01

    Pulmonary fibrosis is a chronic condition characterized by progressive scarring of lung parenchyma. The aim of this study was to examine the effects of an ultramicronized preparation of palmitoylethanolamide (PEA-um(®)), an endogenous fatty acid amide, in mice subjected to idiopathic pulmonary fibrosis. Idiopathic pulmonary fibrosis was induced in male mice by a single intratracheal administration of saline with bleomycin sulphate (1mg/kg body weight) in a volume of 100μL. PEA-um(®) was injected intraperitoneally at 1, 3 or 10mg/kg 1h after bleomycin instillation and daily thereafter. Animals were sacrificed after 7 and 21days by pentobarbitone overdose. One cohort of mice was sacrificed after seven days of bleomycin administration, followed by bronchoalveloar lavage and determination of myeloperoxidase activity, lung edema and histopathology features. In the 21-day cohort, mortality was assessed daily, and surviving mice were sacrificed followed by the above analyses together with immunohistochemical localization of CD8, tumor necrosis factor-α, CD4, interleukin-1β, transforming growth factor-β, inducible nitric oxide synthase and basic fibroblast growth factor. Compared to bleomycin-treated mice, animals that received also PEA-um(®) (3 or 10mg/kg) had significantly decreased weight loss, mortality, inflammation, lung damage at the histological level, and lung fibrosis at 7 and 21days. PEA-um(®) (1mg/kg) did not significantly inhibit the inflammation response and lung fibrosis. This study demonstrates that PEA-um(®) (3 and 10mg/kg) reduces the extent of lung inflammation in a mouse model of idiopathic pulmonary fibrosis.

  3. Experimental Comparison of Calcium Sulfate (CaSO(4)) Scale Deposition on Coated Carbon Steel and Titanium Surfaces

    NASA Astrophysics Data System (ADS)

    Al-Otaibi, Dhawi AbdulRahman

    Calcium Sulfate (CaSO4) deposit reduces heat exchange in heat transfer equipment which adversely affects the equipment performance and plant production. This experimental study was conducted by using the Rotating Cylinder Electrode (RCE) equipment available in the university's Center for Engineering Research (CER/RI) to study and compare the effect of solution hydrodynamics on Calcium Sulfate (CaSO4) scale deposition on coated carbon steel and titanium surfaces. In addition, the Scanning Electron Microscopic was used to examine the morphology and distribution of Calcium Sulfate (CaSO 4) crystals deposited on titanium metal surfaces. In this study, the rotational speed was varied from 100 to 2000 RPM to study the behavior of Calcium Sulfate (CaSO4) accumulation on both materials. Based on the experimental results, Calcium Sulfate (CaSO4) scale obtained in the present study was almost constant on coated carbon steel in which the rate of scale deposition is equal to the rate of scale removal. However, the deposition of Calcium Sulfate (CaSO4) observed on titanium material was increased as the speed increased.

  4. Genome Sequence of a Typical Ultramicrobacterium, Curvibacter sp. Strain PAE-UM, Capable of Phthalate Ester Degradation

    PubMed Central

    Ma, Dan; Hao, Zhenyu; Sun, Rui

    2016-01-01

    Curvibacter sp. strain PAE-UM, isolated from river sediment, is a typical ultramicrobacterium capable of phthalate ester degradation. The genome of Curvibacter sp. PAE-UM consists of 3,284,473 bp, and its information will provide insights into the molecular mechanisms underlying its degradation ability. PMID:26769923

  5. Genome Sequence of a Typical Ultramicrobacterium, Curvibacter sp. Strain PAE-UM, Capable of Phthalate Ester Degradation.

    PubMed

    Ma, Dan; Hao, Zhenyu; Sun, Rui; Bartlam, Mark; Wang, Yingying

    2016-01-14

    Curvibacter sp. strain PAE-UM, isolated from river sediment, is a typical ultramicrobacterium capable of phthalate ester degradation. The genome of Curvibacter sp. PAE-UM consists of 3,284,473 bp, and its information will provide insights into the molecular mechanisms underlying its degradation ability.

  6. Uh, Um, and Autism: Filler Disfluencies as Pragmatic Markers in Adolescents with Optimal Outcomes from Autism Spectrum Disorder.

    PubMed

    Irvine, Christina A; Eigsti, Inge-Marie; Fein, Deborah A

    2016-03-01

    Filler disfluencies--uh and um--are thought to serve distinct discourse functions. We examined fillers in spontaneous speech by youth with autism spectrum disorder (ASD), who struggle with pragmatic language, and by youth with ASD who have achieved an 'optimal outcome' (OO), as well as in peers with typical development (TD). While uh rates did not differ, participants with ASD produced um less frequently than OO or TD groups. Um rate was associated with autism symptom severity, but not executive function or language abilities, suggesting that um serves a pragmatic, listener-oriented function. Moreover, in contrast to minimal production in ASD, the typical OO um production substantiates the normalization of subtle social communication in this population.

  7. CaSO4:DY,Mn: A new and highly sensitive thermoluminescence phosphor for versatile dosimetry

    NASA Astrophysics Data System (ADS)

    Bahl, Shaila; Lochab, S. P.; Kumar, Pratik

    2016-02-01

    With the advent of newer techniques for dose reduction coupled with the development of more sensitive detectors, the radiation doses in radiological medical investigation are decreasing. Nevertheless, keeping the tenet in mind that all radiation doses could entail risk, there is a need to develop more sensitive dosimeters capable of measuring low doses. This paper gives the account of the development of a new and sensitive phosphor CaSO4:Dy,Mn and its characterization. The standard production procedure based on the recrystallization method was used to prepare CaSO4:Dy,Mn. The Thermoluminescence (TL) studies were carried out by exposing it with gamma radiation (Cs-137) from 10 μGy to 100 Gy. The theoretical studies to determine the number of peaks and kinetic parameters related to the TL glow peaks in CaSO4:Dy,Mn was performed using the Computerized Glow Curve Deconvolution (CGCD) method. Experiments were performed to determine optimum concentration of the dopants Dysprosium (Dy) and Mangnese (Mn) in the host CaSO4 so that maximum sensitivity of the phosphor may be achieved. The optimum dopant concentration turned out to be 0.1 mol%. As there were two dopants Dy and Mn their relative ratio were varied in steps of 0.025 keeping the concentration of total dopant (Dy and Mn) 0.1 mol% always. The maximum TL intensity was seen in the CaSO4:Dy(0.025),Mn(0.075) combination. The TL sensitivity of this phosphor was found to be about 2 and 1.8 times higher than that of popular phosphor CaSO4:Dy and LiF:Mg,Cu,P (TLD-700H) respectively. This new phosphor CaSO4:Dy,Mn showed fading of 11% which is similar to that of the standard phosphor CaSO4:Dy. The paper concludes that the new, highly sensitive TL phosphor CaSO4:Dy,Mn has shown higher sensitivity and hence the potential to replace commonly used CaSO4:Dy.

  8. Electron spin resonance and thermoluminescence studies in CaSO4: Dy,Ag phosphor

    NASA Astrophysics Data System (ADS)

    Dhabekar, Bhushan; Menon, Sanjeev; Kumar, Rajesh; Gundu Rao, T. K.; Bhatt, B. C.; Lakshmanan, A. R.

    2005-09-01

    The defect centres formed in the thermoluminescence (TL) phosphor CaSO4 : Dy,Ag are studied using the technique of electron spin resonance (ESR). The Ag co-doped phosphor exhibits three glow peaks around 130°C, 220°C and 375°C, in contrast to the two glow peaks observed in the CaSO4 : Dy phosphor at 130°C and 220°C, at gamma ray dose of 1 Gy when the TL measurements were carried out in the spectral region 300-650 nm. ESR studies show that the additional peak at 375°C correlates with a Ag2+ centre formed owing to γ-irradiation and observable below -170°C. The Ag2+ centre is characterized by an axial g-tensor with principal values g|| = 2.38 and gbottom = 2.41. ESR studies further indicate that the precursor to a centre observable at low temperature (-170°C) appears to act as the recombination centre for the TL peak at 375°C; this radical is characterized by the g-values g|| = 2.0023 and gbottom = 2.0038 and is assigned to the SO_{3}^{-} radical. It is observed that there is more incorporation of Ag in the CaSO4 : Dy system as compared with that in the pure CaSO4 system. The variation of Ag2 + ESR intensity with Ag concentration as well as with dose in the range 0.3-120 kGy is studied. The Ag2 + ESR signal and TL saturate at 2 × 104 Gy, but the intensity of the SO_{3}^{-} radical continues to increase up to the studied dose of 1.2 × 105 Gy. The intensity of the SO_{3}^{-} radical decreases with Ag concentration in CaSO4 : Dy,Ag, in agreement with the TL model proposed in this work.

  9. The merging dwarf galaxy UM 448: chemodynamics of the ionized gas from VLT integral field spectroscopy

    NASA Astrophysics Data System (ADS)

    James, B. L.; Tsamis, Y. G.; Barlow, M. J.; Walsh, J. R.; Westmoquette, M. S.

    2013-01-01

    Using Very Large Telescope/Fibre Large Array Multi Element Spectrograph optical integral field unit observations, we present a detailed study of UM 448, a nearby blue compact galaxy (BCG) previously reported to have an anomalously high N/O abundance ratio. New Technology Telescope/Superb-Seeing Imager images reveal a morphology suggestive of a merger of two systems of contrasting colour, whilst our Hα emission maps resolve UM 448 into three separate regions that do not coincide with the stellar continuum peaks. UM 448 exhibits complex emission line profiles, with most lines consisting of a narrow [full width at half-maximum (FWHM) ≲ 100 km s-1], central component, an underlying broad component (FWHM ˜ 150-300 km s-1) and a third, narrow blueshifted component. Radial velocity maps of all three components show signs of solid body rotation across UM 448, with a projected rotation axis that correlates with the continuum morphology of the galaxy. A spatially resolved, chemodynamical analysis, based on the [O iii] λλ4363, 4959, [N ii] λ6584, [S ii] λλ6716, 6731 and [Ne iii] λ3868 line maps, is presented. Whilst the eastern tail of UM 448 has electron temperatures (Te) that are typical of BCGs, we find a region within the main body of the galaxy where the narrow and broad [O iii] λ4363 line components trace temperatures differing by 5000 K and oxygen abundances differing by 0.4 dex. We measure spatially resolved and integrated ionic and elemental abundances for O, N, S and Ne throughout UM 448, and find that they do not agree, possibly due the flux weighting of Te from the integrated spectrum. This has significant implications for abundances derived from long-slit and integrated spectra of star-forming galaxies in the nearby and distant universe. A region of enhanced N/O ratio is indeed found, extended over a ˜0.6 kpc2 region within the main body of the galaxy. Contrary to previous studies, however, we do not find evidence for a large Wolf-Rayet (WR

  10. VizieR Online Data Catalog: Activity of 70um-selected galaxies (Symeonidis+, 2010)

    NASA Astrophysics Data System (ADS)

    Symeonidis, M.; Rosario, D.; Georgakakis, A.; Harker, J.; Laird, E. S.; Page, M. J.; Willmer, C. N. A.

    2012-01-01

    We present the first active galactic nuclei (AGN) census in a sample of 61 galaxies selected at 70um, a wavelength which should strongly favour the detection of star-forming systems. For the purpose of this study, we take advantage of deep Chandra X-ray and Spitzer infrared (3.6-160um) data, as well as optical spectroscopy and photometry from the Deep Extragalactic Evolutionary Probe 2 (DEEP 2) survey for the Extended Groth Strip (EGS) field, as part of the All-Wavelength Extended Groth Strip International Survey. We investigate spectral line diagnostics ([OIII]/H β and [NeIII]/[OII] ratios, Hδ Balmer absorption line equivalent widths and the strength of the 4000Å break), X-ray luminosities and spectral energy distributions (SEDs). (1 data file).

  11. Variability of the broad absorption lines in the QSO UM 232

    NASA Technical Reports Server (NTRS)

    Barlow, Thomas A.; Junkkarinen, Vesa T.; Burbidge, E. Margaret

    1989-01-01

    Low-resolution spectra of UM 232 taken in 1978, 1979, and 1988 at Lick Observatory are presented. Large changes in the Si IV lambda 1397, CIV lambda 1549, and Al III lambda 1857 broad absorption lines are apparent. The decrease in column density in all three ions and an observed brightening of the QSO suggests that these changes are due to an increase in the ionization level driven by an increase in the central source luminosity. This mechanism has been proposed by Smith and Penston to explain small changes in the absorption spectrum of the QSO 1246-057. The spectra of UM 232 show that the fractional decrease in optical depth is smaller at higher outflow velocies. The structure of the broad absorption-line region (BALR) is investigted by estimating an ionization parameter for each ion species as a function of velocity.

  12. Observations of the new gravitational lens system UM 673 = Q 0142-100

    NASA Astrophysics Data System (ADS)

    Surdej, J.; Magain, P.; Swings, J.-P.; Borgeest, U.; Courvoisier, T. J.-L.; Kayer, R.; Kellermann, K. I.; Kuhr, H.; Refsdal, S.

    1988-06-01

    The authors have recently initiated a high resolution direct imaging survey of a selected sample of highly luminous quasars (HLQs). The observations are carried out with the 2.2 m telescope at ESO, and with the VLA at the NRAO, New Mexico. Following the first observing run at ESO, the authors have reported the discovery of a new gravitational lens system for the HLQ UM 673 = Q 0142-100. Additional observations supporting this interpretation are discussed here. Application of gravitational optometry to this system is given: a value of M0 = 2.4×1011M_sun; is derived for the mass of the lensing galaxy located between UM 673 A and B and a most likely estimate of Δt = 7 weeks is found for the expected delay between the arrival times of a similar variability event in the two lensed images of the quasar (H0 = 75 km s-1Mpc-1, q0 = 0).

  13. Isoalantolactone inhibits UM-SCC-10A cell growth via cell cycle arrest and apoptosis induction.

    PubMed

    Wu, Minjun; Zhang, Hua; Hu, Jiehua; Weng, Zhiyong; Li, Chenyuan; Li, Hong; Zhao, Yan; Mei, Xifan; Ren, Fu; Li, Lihua

    2013-01-01

    Isoalantolactone is a sesquiterpene lactone compound isolated from the roots of Inula helenium L. Previous studies have demonstrated that isoalantolactone possesses antifungal, anti-bacterial, anti-helminthic and anti-proliferative properties in a variety of cells, but there are no studies concerning its effects on head and neck squamous cell carcinoma (HNSCC). In the present study, an MTT assay demonstrated that isoalantolactone has anti-proliferative activity against the HNSCC cell line (UM-SCC-10A). Immunostaining identified that this compound induced UM-SCC-10A cell apoptosis but not necrosis. To explain the molecular mechanisms underlying its effects, flow cytometry and western blot analysis showed that the apoptosis was associated with cell cycle arrest during the G1 phase, up-regulation of p53 and p21, and down-regulation of cyclin D. Furthermore, our results revealed that induction of apoptosis through a mitochondrial pathway led to up-regulation of pro-apoptotic protein expression (Bax), down-regulation of anti-apoptotic protein expression (Bcl-2), mitochondrial release of cytochrome c (Cyto c), reduction of mitochondrial membrane potential (MMP) and activation of caspase-3 (Casp-3). Involvement of the caspase apoptosis pathway was confirmed using caspase inhibitor Z-VAD-FMK pretreatment. Together, our findings suggest that isoalantolactone induced caspase-dependent apoptosis via a mitochondrial pathway and was associated with cell cycle arrest in the G1 phase in UM-SCC-10A cells. Therefore, isoalantolactone may become a potential drug for treating HNSCC.

  14. Fermentation optimization for the production of bioactive polysaccharides from Cordyceps sinensis fungus UM01.

    PubMed

    Wang, Lan-Ying; Cheong, Kit-Leong; Wu, Ding-Tao; Meng, Lan-Zhen; Zhao, Jing; Li, Shao-Ping

    2015-08-01

    The optimal fermentation conditions and medium for the production of bioactive polysaccharides from the mycelium of Cordyceps sinensis fungus UM01 were investigated by using orthogonal design and high performance size exclusion chromatography coupled with multi-angel laser light scattering and refractive index detector (HPSEC-MALLS-RID). Results showed that the optimal temperature, initial pH, rotation speed, medium capacity (ratio of medium volume to the volume of flask bottle) and inoculums volume for the mycelium growth were 15 °C, pH 6.0, 150 rpm, 2/5 (v/v), and 3% (v/v), respectively. Furthermore, bioactive polysaccharides from the mycelium of C. sinensis fungus UM01 were determined as polysaccharide fractions with the molecular weight above 10 kDa. The optimal fermentation medium was determined as a composition of glucose 30.0 g/L, sucrose 30.0 g/L, KH2PO4 1.0 g/L, CaCl2 0.5 g/L, yeast extract 3.0 g/L, and MgCl2 0.1g/L according to the maximum amount of the bioactive polysaccharides (486.16±19.60 mg/L) measured by HPSEC-MALLS/RID. Results are helpful to establish an efficient and controllable fermentation process for the industrial production of bioactive polysaccharides from C. sinensis UM01, and beneficial to develop a unique health and functional product in future.

  15. Extended X-ray absorption fine structure (EXAFS) study of CaSO 4:Dy phosphors

    NASA Astrophysics Data System (ADS)

    Bhattacharyya, D.; Bakshi, A. K.; Ciatto, G.; Aquilanti, G.; Pradhan, A. S.; Pascarelli, S.

    2006-03-01

    Extended X-ray absorption fine structure (EXAFS) measurements have been carried out on CaSO 4:Dy phosphors at the Dy L 3 edge with synchrotron radiation. The data have been analysed to find out the Dy-S and Dy-O bond lengths in the neighborhood of the Dy atoms. Measurements have been carried out over several samples thermally annealed for different cycles at 400 °C in air for 1 h and the change in bond lengths in samples with increasing number of annealing cycles have been studied by analyzing the EXAFS data.

  16. Room and low temperature luminescence properties of CaSO4: Dy , Tm codoped with Li

    NASA Astrophysics Data System (ADS)

    Can, N.; Karalı, T.; Wang, Y.; Townsend, P. D.; Prokic, M.; Canimoglu, A.

    2009-08-01

    Rare earths, especially Dy or Tm doped CaSO4 phosphors are actively studied. They have high sensitivity, a large dynamic range, thermal stability and ease of preparation. Nevertheless, they can be enhanced by inclusion of lithium and this study reports some effects of lithium co-dopant on the TL and radioluminescence (RL) emissions of two TL phosphors. Addition of Li as a co-dopant ion was made either during chemical preparation of the phosphors, or as a binder component mixed with the basic phosphors matrix during the process of pressing and sintering the TLD pellets.

  17. Correlated magnetic resonance imaging and ultramicroscopy (MR-UM) is a tool kit to assess the dynamics of glioma angiogenesis.

    PubMed

    Breckwoldt, Michael O; Bode, Julia; Kurz, Felix T; Hoffmann, Angelika; Ochs, Katharina; Ott, Martina; Deumelandt, Katrin; Krüwel, Thomas; Schwarz, Daniel; Fischer, Manuel; Helluy, Xavier; Milford, David; Kirschbaum, Klara; Solecki, Gergely; Chiblak, Sara; Abdollahi, Amir; Winkler, Frank; Wick, Wolfgang; Platten, Michael; Heiland, Sabine; Bendszus, Martin; Tews, Björn

    2016-02-02

    Neoangiogenesis is a pivotal therapeutic target in glioblastoma. Tumor monitoring requires imaging methods to assess treatment effects and disease progression. Until now mapping of the tumor vasculature has been difficult. We have developed a combined magnetic resonance and optical toolkit to study neoangiogenesis in glioma models. We use in vivo magnetic resonance imaging (MRI) and correlative ultramicroscopy (UM) of ex vivo cleared whole brains to track neovascularization. T2* imaging allows the identification of single vessels in glioma development and the quantification of neovessels over time. Pharmacological VEGF inhibition leads to partial vascular normalization with decreased vessel caliber, density, and permeability. To further resolve the tumor microvasculature, we performed correlated UM of fluorescently labeled microvessels in cleared brains. UM resolved typical features of neoangiogenesis and tumor cell invasion with a spatial resolution of ~5 µm. MR-UM can be used as a platform for three-dimensional mapping and high-resolution quantification of tumor angiogenesis.

  18. X-ray absorption spectroscopy and X-ray photoelectron spectroscopy studies of CaSO 4:Dy thermoluminescent phosphors

    NASA Astrophysics Data System (ADS)

    Bakshi, A. K.; Jha, S. N.; Olivi, L.; Phase, D. M.; Kher, R. K.; Bhattacharyya, D.

    2007-11-01

    Extended X-ray absorption fine structure (EXAFS) measurements have been carried out on CaSO4:Dy phosphor samples at the Dy L3 edge with synchrotron radiation. Measurements were carried out on a set of samples which were subjected to post-preparation annealing at different temperatures and for different cycles. The EXAFS data have been analysed to find the Dy-S and Dy-O bond lengths in the neighbourhood of the Dy atoms in a CaSO4 matrix. The observations from EXAFS measurements were verified with XANES and XPS techniques. On the basis of these measurements, efforts were made to explain the loss of thermoluminescence sensitivity of CaSO4:Dy phosphors after repeated cycles of annealing at 400 °C in air for 1 h.

  19. Complex terbium luminescence centers in spectral transformers based on CaSO4

    NASA Astrophysics Data System (ADS)

    Kudryavtseva, I.; Lushchik, A.; Lushchik, Ch.; Maaroos, A.; Nagirnyi, V.; Pazylbek, S.; Tussupbekova, A.; Vasil'chenko, E.

    2015-11-01

    The blue and green terbium luminescence excitation spectra (5-15 eV) at a temperature of 9 or 300 K have been measured for a set of CaSO4 : Tb3+ phosphors with calcium and terbium ions characterized by fundamental features, which were synthesized by the solid-state reaction method with variations in the composition of the raw material, the type of terbium compounds, and the concentration of introduced terbium. A comprehensive analysis of these data, emission spectra, and decay kinetics (with the rising stage) of the terbium luminescence has revealed that the main luminescence centers in an efficient phosphor with 4 at % Tb3+ each contain four closely spaced Tb3+ ions in calcium positions, as well as Na+ ions and hydrogen-containing radicals. In such complex luminescence centers, cooperative nonradiative resonant transitions in neighboring terbium ions leads to a nearly complete concentration of the terbium luminescence in the green spectral region (5 D 4 → 7 F J ). The quantum yield of the green luminescence in CaSO4 : Tb3+ (4 at %) exceeds unity, QY > 1, in the region of direct excitation of Tb3+ into the 5 d state (~5.9 eV) or excitation of oxyanions near the terbium ions (~8.1 eV).

  20. Thermoluminesence of gamma rays irradiated CaSO4 nanorods doped with different elements

    NASA Astrophysics Data System (ADS)

    Salah, Numan

    2015-01-01

    Nanorods of calcium sulfate (CaSO4) activated by Ag, Cu, Dy, Eu and Tb were synthesized by the co-precipitation technique. They were irradiated by γ-rays in a wide range of exposures and studied for their thermoluminesence (TL) properties. The as-synthesized samples were characterized by scanning electron microscopy (SEM), X-ray diffraction (XRD) and photoluminescence (PL) emission spectra. SEM images show that the samples doped with rare earths elements (i.e. Dy, Eu and Tb) have thinner nanorods than the other samples, while XRD pattern shows a complete crystalline structures in a monoclinic phase. The TL glow curves of these samples show two components. The first one include low temperature glow peaks at around 125 °C, while the second component shows high temperature peaks in the range 230-270 °C. These glow peaks diver from sample to sample by their TL intensity. The TL results are promising, particularly that of Tb and Eu. Tb doped sample is found to be a highly TL sensitive with a prominent glow peak at around 270 °C, while Eu has created very active, high dense electron traps. The later shows quite linear response in the whole studied exposures i.e. 10 Gy-10 kGy. These results show that Eu or Tb doped CaSO4 nanorods might be proper candidates as dosimeters for high doses of ionizing radiations used in irradiation of foods and seeds.

  1. Electronic excitations and self-trapping of electrons and holes in CaSO4

    NASA Astrophysics Data System (ADS)

    Kudryavtseva, I.; Klopov, M.; Lushchik, A.; Lushchik, Ch; Maaroos, A.; Pishtshev, A.

    2014-04-01

    A first-principles study of the electronic properties of a CaSO4 anhydrite structural phase has been performed. A theoretical estimation for the fundamental band gap (p → s transitions) is Eg = 9.6 eV and a proper threshold for p → d transitions is Epd = 10.8 eV. These values agree with the data obtained for a set of CaSO4 doped with Gd3+, Dy3+, Tm3+ and Tb3+ ions using the methods of low-temperature highly sensitive luminescence and thermoactivation spectroscopy. The results are consistent with theoretical predictions of a possible low-temperature self-trapping of oxygen p-holes. The hopping diffusion of hole polarons starts above ˜40 K and is accompanied by a ˜50-60 K peak of thermally stimulated luminescence of RE3+ ions caused due to the recombination of hole polarons with the electrons localized at RE3+. There is no direct evidence of the self-trapping of heavy d-electrons, however, one can argue that their motion rather differs from that of conduction s-electrons.

  2. Design of a ROIC with 15um pitch for MWIR FPAs

    NASA Astrophysics Data System (ADS)

    Liang, Qinghua; Jiang, Dazhao; Chen, Honglei; Zhang, Qiwen; Ding, Ruijun

    2015-10-01

    A 640×512 readout integrated circuit (ROIC) with 15um pixel pitch for middle-wave infrared focal plane arrays (MWIR FPAs) is designed in this paper. The 15um pixel pitch presents several challenges to the ROIC design, such as achieving the required charge storage capacity to preserve the high SNR and reading or processing the pixel signals correctly to achieve the required frame rate. A novel structure that four neighboring pixels share one integration capacitor is presented as a feasible approach to getting a large charge capacity in the limited pixel area. Meanwhile, the pixel circuit chooses the direct injection (DI) which occupies the small layout area as the input stage for MW and contains two sample and hold modules to further increase the charge capacity. Moreover,the peripheral analog signal chain circuit, which is composed of a PMOS source follower, a column amplifier and the complementary output stage, is designed to transfer the signals from unit cell with less voltage loss,lower power consumption, lower noise and higher linearity. More importantly, in our design, only half chain circuit are required therefore the corresponding power consumption will be reduced greatly. In order to accommodate this design, two kinds of pixel signal readout sequences are compared. By adopting the 0.18um 1P6M mixed signal CMOS process, the circuit architecture can make the effective charge capacity of 13Me- per pixel with 1.38V final output range. The 4×4 circuit layout will be fulfilled as a whole and in this way the effective integration capacitor can be increased. According to the simulation results, this circuit works well under 3.3V power supply and achieves 10MHZ readout rate and less than 0.1% nonlinearity.

  3. Cliché fabrication method using precise roll printing process with 5 um pattern width

    NASA Astrophysics Data System (ADS)

    Shin, Yejin; Kim, Inyoung; Oh, Dong-Ho; Lee, Taik-Min

    2016-09-01

    Among the printing processes for printed electronic devices, gravure offset and reverse offset method have drawn attention for its fine pattern printing possibility. These printing methods use cliché, which has critical effect on the final product precision and quality. In this research, a novel precise cliché replica method is proposed. It consists of copper sputtering, precise mask pattern printing with 5 um width using reverse offset printing, Ni electroplating, lift-off, etching, and DLC coating. We finally compare the fabricated replica cliché with the original one and print out precise patterns using the replica cliché.

  4. VizieR Online Data Catalog: Galactic planetary nebulae 24um observations (Phillips+, 2011)

    NASA Astrophysics Data System (ADS)

    Phillips, J. P.; Marquez-Lugo, R. A.

    2015-07-01

    We have acquired 24um profiles images and fluxes for 224 Galactic PNe. The positions of the sources were taken from the Acker et al. (1992, Cat. V/84), MASH I (Parker et al., 2006MNRAS.373...79P, Cat. V/127) and MASH II (Miszalski et al., 2008MNRAS.384..525M, Cat. V/127) catalogues, and correspond to the so-called 'true' PNe whose identification is regarded as being highly probable. Sources designated as 'likely' or 'possible' are excluded from this analysis. The MISPGAL results were taken between 2005 and 2006 using the mips. (1 data file).

  5. Wissenschaft, die unsere Kultur verändert. Tiefenschichten des Streits um die Evolutionstheorie

    NASA Astrophysics Data System (ADS)

    Patzelt, Werner J.

    Die Evolutionstheorie ist eine der erfolgreichsten wissenschaftlichen Theorien. Sie erlaubt es, unsere Herkunft zu verstehen und riskante Merkmale gerade der menschlichen Spezies zu begreifen. Zugleich ist die Evolutionstheorie eine der umstrittensten Theorien. Das liegt nicht an ihrer empirischen Tragfähigkeit, sondern an ihrem Gegenstand. Sie handelt nämlich nicht nur - wie Hunderte andere wissenschaftliche Theorien - von der "Welt da draußen“, sondern vor allem auch von uns selbst und von unserem Platz in dieser Welt. Den einen gilt sie obendrein als Überwinderin religiösen Aberglaubens, den anderen als neuer Zugang zu Gott und seinem Wirken in der Welt. Ferner sehen die einen in der Evolution eine unbezweifelbare Tatsache gleich der Schwerkraft oder dem Holocaust, die anderen aber eine - noch oder dauerhaft - unbewiesene Hypothese oder gar eine falsche Schöpfungslehre. Und während die meisten Streitfragen solcher Art nach wechselseitig akzeptierten Regeln ‚normaler Wissenschaft‘ geklärt werden, wird bei der Frage nach dem Woher unserer Spezies und Kultur die intellektuelle Zuständigkeit von Wissenschaft mitunter überhaupt bezweifelt. Anscheinend geht es schon um recht tiefe Schichten unserer Kultur und nicht nur der wissenschaftlichen, wenn - wie seit 150 Jahren - um die Evolutionstheorie gestritten wird. Wie sehen diese Schichten aus?

  6. Traitement chirurgical des fractures articulaires du calcanéum par plaque vissée

    PubMed Central

    Hammou, Nassreddine; Abid, Hatim; Shimi, Mohammed; El Ibrahimi, Abdelhalim; El Mrini, Abdelmajid

    2015-01-01

    Les fractures du calcanéum sont peu fréquentes mais le plus souvent graves. Le traitement chirurgical par plaque vissée est ardemment défendu. L'objectif de notre travail rétrospectif est d’évaluer les résultats du traitement chirurgical des fractures articulaires du calcanéum à travers une série de 12 patients opérée aux service d'orthopédie du CHU Hassan II de Fès sur une durée de 3 ans, et les comparer aux données de la littérature. L’âge moyen dans notre série était de 34 ans, le geste opératoire était réalisé au 7ème jour. Tous nos patient ont bénéficie d'une réduction à foyer ouvert avec une ostéosynthèse par plaques vissées. Le recul moyen était de 12 mois et les résultats fonctionnels ont été évaluer selon le score de Kitaoka. PMID:26161214

  7. Uh and um in children with autism spectrum disorders or language impairment.

    PubMed

    Gorman, Kyle; Olson, Lindsay; Hill, Alison Presmanes; Lunsford, Rebecca; Heeman, Peter A; van Santen, Jan P H

    2016-08-01

    Atypical pragmatic language is often present in individuals with autism spectrum disorders (ASD), along with delays or deficits in structural language. This study investigated the use of the "fillers" uh and um by children ages 4-8 during the autism diagnostic observation schedule. Fillers reflect speakers' difficulties with planning and delivering speech, but they also serve communicative purposes, such as negotiating control of the floor or conveying uncertainty. We hypothesized that children with ASD would use different patterns of fillers compared to peers with typical development or with specific language impairment (SLI), reflecting differences in social ability and communicative intent. Regression analyses revealed that children in the ASD group were much less likely to use um than children in the other two groups. Filler use is an easy-to-quantify feature of behavior that, in concert with other observations, may help to distinguish ASD from SLI. Autism Res 2016, 9: 854-865. © 2016 International Society for Autism Research, Wiley Periodicals, Inc.

  8. MIPAS observations of ozone chemiluminescence at 5 um analysed by a new non-lte model

    NASA Astrophysics Data System (ADS)

    Kaufmann, M.; Toselli, B.; Fernandez, R.; Gil-Lopez, S.; Lopez-Puertas, M.; Funke, B.; Stiller, G.; Hoffmann, L.; Riese, M.

    The proper characterization of ozone mid-ir radiances under non-LTE conditions is very important for the retrieval of mesospheric constituents such as ozone or carbon monoxide A recent study of Kaufmann et al 2006 indicated very large Envisat-MIPAS radiances at 4 8 um and suggested significant changes to standard non-LTE models of ozone to fit the measurements To verify and extend these results we developed a new ozone non-LTE model for the main vibrational-translational VT relaxation channels of ozone based on the theory of Schwartz-Slawsky-Herzfeld The VT relaxation rates are compared with the standard approach using a Landau-Teller type scaling law In addition to VT relaxation we also consider vibrational-vibrational energy exchange with O2 for various transitions and demonstrate the importance of this relaxation path for many vibrational levels Finally the non-LTE model parameters are constrained by comparing simulated 5um radiances with observations of the MIPAS instrument at stratospheric altitudes where the atmospheric state can be characterized from MIPAS measurements not affected by non-LTE

  9. Phase relation of CaSO4 at high pressure and temperature up to 90 GPa and 2300 K

    NASA Astrophysics Data System (ADS)

    Fujii, Taku; Ohfuji, Hiroaki; Inoue, Toru

    2016-05-01

    Calcium sulfate (CaSO4), one of the major sulfate minerals in the Earth's crust, is expected to play a major role in sulfur recycling into the deep mantle. Here, we investigated the crystal structure and phase relation of CaSO4 up to ~90 GPa and 2300 K through a series of high-pressure experiments combined with in situ X-ray diffraction. CaSO4 forms three thermodynamically stable polymorphs: anhydrite (stable below 3 GPa), monazite-type phase (stable between 3 and ~13 GPa) and barite-type phase (stable up to at least 93 GPa). Anhydrite to monazite-type phase transition is induced by pressure even at room temperature, while monazite- to barite-type transition requires heating at least to 1500 K at ~20 GPa. The barite-type phase cannot always be quenched from high temperature and is distorted to metastable AgMnO4-type structure or another modified barite structure depending on pressure. We obtained the pressure-volume data and density of anhydrite, monazite- and barite-type phases and found that their densities are lower than those calculated from the PREM model in the studied P-T conditions. This suggests that CaSO4 is gravitationally unstable in the mantle and fluid/melt phase into which sulfur dissolves and/or sulfate-sulfide speciation may play a major role in the sulfur recycling into the deep Earth.

  10. Hemangioblastomas de fosa posterior: Reporte de 16 casos y revisión de la literatura

    PubMed Central

    Campero, Alvaro; Ajler, Pablo; Fernandez, Julio; Isolan, Gustavo; Paiz, Martin; Rivadeneira, Conrado

    2016-01-01

    Resumen Objetivo: El propósito del presente trabajo es presentar los resultados de 16 pacientes con diagnóstico de hemangioblastoma de fosa posterior (HBFP), operados con técnicas microquirúrgicas. Método: Desde junio de 2005 a diciembre de 2015, 16 pacientes con diagnóstico de HBFP fueron intervenidos quirúrgicamente. Se evaluó: sexo, edad, tipo de lesión (quística con nódulo, quística sin nódulo, sólida y sólida-quística), sintomatología y resultados postoperatorios. Resultados: De los 16 pacientes intervenidos, 11 fueron varones y 5 mujeres. La edad promedio fue de 44 años. La forma más frecuente fue quística con nódulo (57%), seguida por forma sólida (31%). Un solo caso presentó la forma quística sin nódulo (6%), y uno solo la forma sólido-quística (6%). La sintomatología más frecuente fue cefalea acompañada de síndrome cerebeloso (43%), seguido de síndrome de hipertensión endocraneana (25%). En todos los casos la resección fue completa, siendo necesario en un caso una embolización previa. Como complicaciones postoperatorias, 2 pacientes presentaron ataxia (mejoró al cabo de 3 meses), y 1 paciente presentó una fístula de LCR (se solucionó con un drenaje espinal externo). Se registró un óbito por complicaciones postoperatorias. Conclusión: Lo más frecuente de ver en pacientes con HBFP es la forma quística con nódulo, siendo su sintomatología predominante la cefalea acompañada de síndrome cerebeloso. La resección quirúrgica completa es posible, con una baja tasa de morbimortalidad. PMID:27999708

  11. Detector Technologies for Sub-500um High-Sensitivity PET Imaging via a Novel PET Insert Approach

    SciTech Connect

    Tai, Yuan-Chuan

    2011-12-21

    The objective of this project was to develop detector technologies that would enable an ultrahigh resolution Virtual Pinhole (VP) PET insert device to provide sub-500 um resolution high-sensitivity PET imaging of a mouse in the future. To achieve this goal, we proposed to develop and characterize finely pixellated cadmium zinc telluride (CZT) detectors and the associated readout electronics with the following specific aims: 1. Develop pixellated CZT detectors with 350um pitches using 2-5 mm substrates; characterize their spatial, energy and timing performance through experiments; and optimize the anode design with steering grid if found necessary. 2. Develop a high-bandwidth readout system using a novel ASIC that can be directly bonded to CZT detectors with 2048 anodes of 350um pitches; optimize its overall performance for VP-PET applications considering the tradeoffs between spatial resolution (in 3D), count rate capability, timing and energy resolutions. 3. Evaluate the performance of a VP-PET insert based on the proposed detector technology through Monte Carlo simulation and experimental validation. Overall, we have completed all three specific aims and demonstrated that pixelated CZT detectors of 350um pitches, combined with VP-PET geometry, can provide PET image resolution of ~460 um FWHM for small animal imaging applications.

  12. Clinical Performance and Management Outcomes with the DecisionDx-UM Gene Expression Profile Test in a Prospective Multicenter Study.

    PubMed

    Plasseraud, Kristen Meldi; Cook, Robert W; Tsai, Tony; Shildkrot, Yevgeniy; Middlebrook, Brooke; Maetzold, Derek; Wilkinson, Jeff; Stone, John; Johnson, Clare; Oelschlager, Kristen; Aaberg, Thomas M

    2016-01-01

    Uveal melanoma management is challenging due to its metastatic propensity. DecisionDx-UM is a prospectively validated molecular test that interrogates primary tumor biology to provide objective information about metastatic potential that can be used in determining appropriate patient care. To evaluate the continued clinical validity and utility of DecisionDx-UM, beginning March 2010, 70 patients were enrolled in a prospective, multicenter, IRB-approved study to document patient management differences and clinical outcomes associated with low-risk Class 1 and high-risk Class 2 results indicated by DecisionDx-UM testing. Thirty-seven patients in the prospective study were Class 1 and 33 were Class 2. Class 1 patients had 100% 3-year metastasis-free survival compared to 63% for Class 2 (log rank test p = 0.003) with 27.3 median follow-up months in this interim analysis. Class 2 patients received significantly higher-intensity monitoring and more oncology/clinical trial referrals compared to Class 1 patients (Fisher's exact test p = 2.1 × 10(-13) and p = 0.04, resp.). The results of this study provide additional, prospective evidence in an independent cohort of patients that Class 1 and Class 2 patients are managed according to the differential metastatic risk indicated by DecisionDx-UM. The trial is registered with Clinical Application of DecisionDx-UM Gene Expression Assay Results (NCT02376920).

  13. Thermoluminescence and photoluminescence of cerium doped CaSO 4 nanosheets

    NASA Astrophysics Data System (ADS)

    Zahedifar, M.; Mehrabi, M.

    2010-12-01

    Thermoluminescence (TL) and photoluminescence (PL) characteristics of CaSO 4:Ce nanocrystalline prepared by hydrothermal method has been studied. Its TL glow curve contains three overlapping glow peaks at around 490, 505 and 521 K. Emission spectra band at 303 and 324 nm were observed for the orthorhombic phase of nanosheets. TL response of the prepared nanocrystalline to β and γ radiation was studied and the sensitivity of the nanosheets was found much more than that of analogous microcrystalline and is around 10 times higher than the well known high sensitive TL dosimeter LiF:Mg, Cu, P (GR-200) hot-pressed chips. TL kinetic parameters of this nanocrystalline are also presented.

  14. Carbon ions irradiation on nano- and microcrystalline CaSO4 : Dy

    NASA Astrophysics Data System (ADS)

    Salah, Numan

    2008-08-01

    Nanoparticles of CaSO4 : Dy phosphor with a particle size of around 30 nm have been prepared by the chemical co-precipitation technique. Pellet samples of the nanomaterials were irradiated by a 75 MeV C6+ ion beam at the fluence range 1 × 109-1 × 1013 ions cm-2. Thermoluminescence (TL) glow curves of the irradiated samples were recorded and studied. The microcrystalline form of this sample is also included in the study with the aim of reporting a comparative measurement. The TL analysis shows that the glow curve of the nanomaterial has two peaks at around 166 and 210 °C. These peaks are similar to those induced in the microcrystalline sample with a slight difference in their TL response. The second peak is more prominent in the case of the microcrystalline sample at low fluences, while the first one dominates in the nanostructured sample mainly at higher fluences. The TRIM code based on Monte Carlo simulation was also used for calculating some ion beam parameters. Dosimetric properties of the carbon ion beam irradiated materials show that the nanostructure material has excellent features such as a simple glow curve structure and a linear TL response over a wider range than the corresponding microcrystalline sample. These results show that the nanostructure form of CaSO4 : Dy might be useful for detecting the high doses of carbon ions used in radiotherapy. Thermal analysis of the prepared nano- and microcrystalline materials was also done in the range 50-500 °C using thermogravimetry analysis and differential thermal analysis. No phase transitions within this range of heating for both the materials are observed.

  15. Is the long case dead? 'Uh, I don't think so': the Uh/Um Index.

    PubMed

    Duvivier, Robbert; Veysey, Martin

    2016-12-01

    Current tools for clinical assessment are tedious and time-consuming, particularly the dreadful long case. There is a need for novel instruments that incorporate other aspects of competence. We propose such a method, namely the Uh/Um Index. Our innovation paper describes the rationale for using speech dysfluency and occurrences of filler words such as 'uh' and 'um' as a proxy for competence. This appears to have won initial support from senior clinicians in our institution. Additional research is needed (non-restricted grants are welcomed) to establish rigorous standard setting and to fund our attendance at overseas conferences to make the Uh/Um Index the new buzzword in medical education.

  16. VizieR Online Data Catalog: XMM survey of 12um selected galaxies (Brightman+, 2011)

    NASA Astrophysics Data System (ADS)

    Brightman, M.; Nandra, K.

    2011-11-01

    We present an X-ray spectral analysis of 126 galaxies of the 12um galaxy sample (Rush et al. 1993, Cat. VII/157). By studying this sample at X-ray wavelengths, we aim to determine the intrinsic power, continuum shape and obscuration level in these sources. We improve upon previous works by the use of superior data in the form of higher signal-to-noise ratio spectra, finer spectral resolution and a broader bandpass from XMM-Newton. We pay particular attention to Compton thick active galactic nucleus (AGN) with the help of new spectral fitting models that we have produced, which are based on Monte Carlo simulations of X-ray radiative transfer, using both a spherical and torus geometry, and taking into account Compton scattering and iron fluorescence. (8 data files).

  17. Comparative genomic analysis of Mycobacterium iranicum UM_TJL against representative mycobacterial species suggests its environmental origin.

    PubMed

    Tan, Joon Liang; Ngeow, Yun Fong; Wee, Wei Yee; Wong, Guat Jah; Ng, Hien Fuh; Choo, Siew Woh

    2014-11-24

    Mycobacterium iranicum is a newly reported mycobacterial species. We present the first comparative study of M. iranicum UM_TJL and other mycobacteria. We found M. iranicum to have a close genetic association with environmental mycobacteria infrequently associated with human infections. Nonetheless, UM_TJL is also equipped with many virulence genes (some of which appear to be the consequence of transduction-related gene transfer) that have been identified in established human pathogens. Taken all together, our data suggest that M. iranicum is an environmental bacterium adapted for pathogenicity in the human host. This comparative study provides important clues and forms the basis for future functional studies on this mycobacterium.

  18. MiR-222 targeted PUMA to improve sensitization of UM1 cells to cisplatin.

    PubMed

    Jiang, Fangfang; Zhao, Wei; Zhou, Lijie; Liu, Zifeng; Li, Wenqing; Yu, Dongsheng

    2014-12-02

    microRNAs have been shown to play critical roles in regulating the chemosensitivity of cancer cells. As a member of the oncogenic miRNAs (oncomiRs), miR-222 has been reported to drive the oncogenesis of many types of malignancies. However, little is known concerning the specific role of miR-222 in human oral squamous cell carcinoma (OSCC). The present study explored the role and mechanism of miR-222 in increasing the expression of p53 up-regulated modulator of apoptosis (PUMA) and enhancing the sensitivity of OSCC to cisplatin (CDDP). Results showed that antisense (As)-miR-222 inhibits the expression of miR-222. In contrast, PUMA was dramaticallyup-regulated. IC50 values were significantly decreased in cells treated with As-miR-222 combined with CDDP, to a greater extent than in cells treated with CDDP alone. Furthermore, As-miR-222 enhanced apoptosis and inhibited the invasiveness of UM1 cells. Analysis of the above data suggested that, in UM1 cells, there might be a regulatory loop between miR-222 and PUMA, and that miR-222 inhibition increased the chemosensitivity to CDDP. These findings demonstrated that down-regulation of miR-222 could enhance the chemosensitivity of human OSCC cells to CDDP, and that the combination of As-miR-222 and CDDP could be an effective therapeutic strategy by boosting the expression of PUMA for controlling the growth of OSCC.

  19. Correlated magnetic resonance imaging and ultramicroscopy (MR-UM) is a tool kit to assess the dynamics of glioma angiogenesis

    PubMed Central

    Breckwoldt, Michael O; Bode, Julia; Kurz, Felix T; Hoffmann, Angelika; Ochs, Katharina; Ott, Martina; Deumelandt, Katrin; Krüwel, Thomas; Schwarz, Daniel; Fischer, Manuel; Helluy, Xavier; Milford, David; Kirschbaum, Klara; Solecki, Gergely; Chiblak, Sara; Abdollahi, Amir; Winkler, Frank; Wick, Wolfgang; Platten, Michael; Heiland, Sabine; Bendszus, Martin; Tews, Björn

    2016-01-01

    Neoangiogenesis is a pivotal therapeutic target in glioblastoma. Tumor monitoring requires imaging methods to assess treatment effects and disease progression. Until now mapping of the tumor vasculature has been difficult. We have developed a combined magnetic resonance and optical toolkit to study neoangiogenesis in glioma models. We use in vivo magnetic resonance imaging (MRI) and correlative ultramicroscopy (UM) of ex vivo cleared whole brains to track neovascularization. T2* imaging allows the identification of single vessels in glioma development and the quantification of neovessels over time. Pharmacological VEGF inhibition leads to partial vascular normalization with decreased vessel caliber, density, and permeability. To further resolve the tumor microvasculature, we performed correlated UM of fluorescently labeled microvessels in cleared brains. UM resolved typical features of neoangiogenesis and tumor cell invasion with a spatial resolution of ~5 µm. MR-UM can be used as a platform for three-dimensional mapping and high-resolution quantification of tumor angiogenesis. DOI: http://dx.doi.org/10.7554/eLife.11712.001 PMID:26830460

  20. "Uh," "Um," and Autism: Filler Disfluencies as Pragmatic Markers in Adolescents with Optimal Outcomes from Autism Spectrum Disorder

    ERIC Educational Resources Information Center

    Irvine, Christina A.; Eigsti, Inge-Marie; Fein, Deborah A.

    2016-01-01

    Filler disfluencies--"uh" and "um"--are thought to serve distinct discourse functions. We examined fillers in spontaneous speech by youth with autism spectrum disorder (ASD), who struggle with pragmatic language, and by youth with ASD who have achieved an "optimal outcome" (OO), as well as in peers with typical…

  1. The fungal UmSrt1 and maize ZmSUT1 sucrose transporters battle for plant sugar resources.

    PubMed

    Wittek, Anke; Dreyer, Ingo; Al-Rasheid, Khaled A S; Sauer, Norbert; Hedrich, Rainer; Geiger, Dietmar

    2017-03-15

    The biotrophic fungus Ustilago maydis causes the corn smut disease inducing tumor formation in its host Zea mays. Upon infection, the fungal hyphae invaginate the plasma membrane of infected maize cells establishing an interface where pathogen and host are separated only by their plasma membranes. At this interface the fungal and maize sucrose transporters, UmSrt1 and ZmSUT1, compete for extracellular sucrose in the corn smut/maize pathosystem. Here we biophysically characterized ZmSUT1 and UmSrt1 in Xenopus oocytes with respect to their voltage-, pH- and substrate-dependence and determined affinities towards protons and sucrose. In contrast to ZmSUT1, UmSrt1 has a high-affinity for sucrose and is relatively pH- and voltage-independent. Using these quantitative parameters, we developed a mathematical model to simulate the competition for extracellular sucrose at the contact zone between the fungus and the host plant. This approach revealed that UmSrt1 exploits the apoplastic sucrose resource, which forces the plant transporter into a sucrose export mode providing the fungus with sugar from the phloem. Importantly, the high sucrose concentration in the phloem appeared disadvantageous for the ZmSUT1, preventing sucrose recovery from the apoplastic space in the fungus/plant interface.

  2. "Um, I Can Tell You're Lying": Linguistic Markers of Deception versus Truth-Telling in Speech

    ERIC Educational Resources Information Center

    Arciuli, Joanne; Mallard, David; Villar, Gina

    2010-01-01

    Lying is a deliberate attempt to transmit messages that mislead others. Analysis of language behaviors holds great promise as an objective method of detecting deception. The current study reports on the frequency of use and acoustic nature of "um" and "like" during laboratory-elicited lying versus truth-telling. Results obtained using a…

  3. La implantacion del enfoque constructivista en el aula de ciencia: Estudio de caso multiple

    NASA Astrophysics Data System (ADS)

    Arroyo Betancourt, Luz I.

    Esta investigacion estudia la implantacion del enfoque constructivista en tres aulas de ciencia del contexto puertorriqueno. Se auscultaron las practicas educativas que utilizan maestras consideradas constructivistas y la correspondencia de sus practicas educativas con los elementos esenciales de la didactica que proponen los teoricos de los planteamientos constructivistas. Se ausculto, ademas, a que vision del enfoque constructivista responden las expresiones de las maestras acerca de su practica educativa y como compara con su quehacer, a la luz de los elementos esenciales de las visiones constructivistas piagetiana, social y radical. Se utilizo el diseno de estudio descriptivo de caso multiple. El estudio se baso en entrevistas a profundidad, revision de documentos y observacion no participativa a la sala de clases. El contexto fueron tres escuelas publicas de la Region Educativa de San Juan, una elemental, una intermedia y una superior. Los resultados confirmaron que la transicion hacia el enfoque constructivista es un proceso que toma tiempo, dedicacion y la participacion en adiestramientos y readiestramientos acerca del nuevo enfoque. Las maestras coinciden en la mayoria de las practicas educativas que utilizan para implantar el enfoque constructivista de ensenanza y difieren en algunas debido, probablemente, a que han tenido que adaptarlas a los correspondientes niveles de ensenanza: elemental, intermedio y superior. Dos de las maestras planifican por conceptos generadores, mientras que una de ellas planifica siguiendo la guia que recibe del Departamento de Educacion. Difieren ademas, en el enfasis que confieren al inquirir cientifico. Con relacion a la correspondencia entre la vision manifestada por las maestras a la luz de las visiones piagetiana, social y radical, aparentemente, las preguntas del protocolo de entrevistas no lograron evocar la informacion con suficiente profundidad, por lo que la investigadora tuvo que inferir las visiones de las

  4. Microwave-Assisted Extraction, Chemical Structures, and Chain Conformation of Polysaccharides from a Novel Cordyceps Sinensis Fungus UM01.

    PubMed

    Cheong, Kit-Leong; Wang, Lan-Ying; Wu, Ding-Tao; Hu, De-Jun; Zhao, Jing; Li, Shao-Ping

    2016-09-01

    Cordyceps sinensis is a well-known tonic food with broad medicinal properties. The aim of the present study was to investigate the optimization of microwave-assisted extraction (MAE) and characterize chemical structures and chain conformation of polysaccharides from a novel C. sinensis fungus UM01. Ion-exchange and gel filtration chromatography were used to purify the polysaccharides. The chemical structure of purified polysaccharide was determined through gas chromatography-mass spectrometry. Moreover, high performance size exclusion chromatography combined with refractive index detector and multiangle laser light scattering were conducted to analyze the molecular weight (Mw ) and chain conformation of purified polysaccharide. Based on the orthogonal design L9 , optimal MAE conditions could be obtained through 1300 W of microwave power, with a 5-min irradiation time at a solid to water ratio of 1:60, generating the highest extraction yield of 6.20%. Subsequently, the polysaccharide UM01-S1 was purified. The UM01-S1 is a glucan-type polysaccharide with a (1→4)-β-d-glucosyl backbone and branching points located at O-3 of Glcp with a terminal-d-Glcp. The Mw , radius of gyration (Rg ) and hydrodynamic radius (Rh ) of UM01-S1 were determined as 5.442 × 10(6)  Da, 21.8 and 20.2 nm, respectively. Using the polymer solution theory, the exponent (ν) value of the power law function was calculated as 0.38, and the shape factor (ρ = Rg /Rh ) was 1.079, indicating that UM01-S1 has a sphere-like conformation with a branched structure in an aqueous solution. These results provide fundamental information for the future application of polysaccharides from cultured C. sinensis in health and functional food area.

  5. A Report to the Joint Chairs of the Senate Budget and Taxation Committee and the House Appropriations Committee on the Workload of the UMS Faculty.

    ERIC Educational Resources Information Center

    Maryland Univ., College Park.

    This report provides data and recommendations on the workload and productivity of University of Maryland System (UMS) faculty. It outlines the state budgetary policy that mandates the report and explains UMS policy on faculty workload. The data in the report reflect teaching standards in place in 1993-94, prior to the adoption of the current UMS…

  6. Nano-fibrin stabilized CaSO4 crystals incorporated injectable chitin composite hydrogel for enhanced angiogenesis & osteogenesis.

    PubMed

    Arun Kumar, R; Sivashanmugam, A; Deepthi, S; Bumgardner, Joel D; Nair, Shantikumar V; Jayakumar, R

    2016-04-20

    Calcium sulfate (CaSO4), an excellent biodegradable bone forming agent that is an ideal choice as additive in gels, however, its disadvantage being poor gel rheology and angiogenesis. Here, we have synthesized chitin-CaSO4-nano-fibrin based injectable gel system which shows improved rheology and angiogenic potential. Rheological studies showed that the composite gel was a shear thinning gel with elastic modulus of 15.4±0.275kPa; a 1.67 fold increase over chitin control. SEM and XRD analyses revealed the effect of nano-fibrin (nFibrin) in transforming CaSO4 crystal shape from needle to hexagonal. It also masked the retarding effect of CaSO4 towards in vitro early cell attachment and angiogenesis using rabbit adipose derived mesenchymal stem cells (rASCs) and HUVECs, respectively. rASCs osteogenesis was confirmed by spectrophotometric endpoint assay, which showed 6-fold early increase in alkaline phosphatase levels and immuno-cytochemistry analysis. These in vitro results highlight the potential of injectable chitin-CaSO4-nFibrin gel for osteo-regeneration via enhanced angiogenesis.

  7. Thermoluminescence (TL) properties and x-ray diffraction (XRD) analysis of high purity CaSO4:Dy TL material

    NASA Astrophysics Data System (ADS)

    Kamarudin, Nadira; Abdullah, Wan Saffiey Wan; Hamid, Muhammad Azmi Abdul; Dollah, Mohd Taufik

    2014-09-01

    This paper presents the characterization and TL properties of dysprosium (Dy) doped calcium sulfate (CaSO4) TL material produced by co-precipitation technique with 0.5mol% concentration of dopant. The morphology of the produced TL material was studied using scanning electron microscope (SEM) and the micrograph shows that rectangular parallelepiped shaped crystal with the average of 150 μm in length were produced. The crystallinity of the produced powder was studied using x-ray powder diffraction (XRD). The XRD spectra show that the TL material produced is high purity anhydrite CaSO4 with average crystallite size of 74 nm with orthorhombic crystal system. The TL behavior of produced CaSO4:Dy was studied using a TLD reader after exposure to gamma ray by Co60 source with the doses of 1,5 and 10 Gy. The glow curve shows linear response with glow peak around 230°C which is desired development in the field of radiation dosimetry.

  8. Operational experience of electronic active personal dosemeter and comparison with CaSo4:Dy TL dosemeter in Indian PHWR.

    PubMed

    Singh, Vishwanath P; Managanvi, S S; Bihari, R R; Bhat, H R

    2013-01-01

    Direct reading dosemeter has been used for day-to-day radiation exposure control and management for last four decades in Indian nuclear power plants (NPPs). Recently new real time, alarm and pre-alarm on equivalent dose/dose rate, storage of dose/dose rate and maximum dose rate, user-friendly electronic active personal dosemeter (APD) has been implemented into practice for the first time at Kaiga Atomic Power Station-3&4,  of Indian NPPs. The dosemeter showed tolerance level (L) 0.1085±0.0450 compared with 0.1869±0.0729 (average±SD) for CaSO4:Dy, TL dosemeter, having narrow range trumpet curve, nil electromagnetic interference. Records of >29 000 for APD and TL dosemeter were analysed for comparasion of the measurement of the individual dose. APD followed general acceptance rule of ±25 % for dose >1 mSv. Monthly Station collective dose by TL dosemeters and APD for normal reactor operation as well as outage are found in good agreement. Operational experiences and statistical analysis support that an APD dosemeter is reasonably equivalent to CaSO4:Dy TL dosemeter. The accuracy, reproducibility and repeatability of the measurement of radiation for (137)Cs are comparable with CaSO4:Dy, TL dosemeter. Operational experience of APD during the normal operation as well as outage showed as one of the best ALARA tool for occupational dose monitoring, control, management and future outage planning.

  9. Ford/BASF/UM Activities in Support of the Hydrogen Storage Engineering Center of Excellence

    SciTech Connect

    Veenstra, Mike; Purewal, Justin; Xu, Chunchuan; Yang, Jun; Blaser, Rachel; Sudik, Andrea; Siegel, Don; Ming, Yang; Liu, Dong'an; Chi, Hang; Gaab, Manuela; Arnold, Lena; Muller, Ulrich

    2015-06-30

    Widespread adoption of hydrogen as a vehicular fuel depends critically on the development of low-cost, on-board hydrogen storage technologies capable of achieving high energy densities and fast kinetics for hydrogen uptake and release. As present-day technologies -- which rely on physical storage methods such as compressed hydrogen -- are incapable of attaining established Department of Energy (DOE) targets, development of materials-based approaches for storing hydrogen have garnered increasing attention. Material-based storage technologies have potential to store hydrogen beyond twice the density of liquid hydrogen. To hasten development of these ‘hydride’ materials, the DOE previously established three centers of excellence for materials storage R&D associated with the key classes of materials: metal hydrides, chemical hydrogen, and adsorbents. While these centers made progress in identifying new storage materials, the challenges associated with the engineering of the system around a candidate storage material are in need of further advancement. In 2009 the DOE established the Hydrogen Storage Engineering Center of Excellence with the objective of developing innovative engineering concepts for materials-based hydrogen storage systems. As a partner in the Hydrogen Storage Engineering Center of Excellence, the Ford-UM-BASF team conducted a multi-faceted research program that addresses key engineering challenges associated with the development of materials-based hydrogen storage systems. First, we developed a novel framework that allowed for a material-based hydrogen storage system to be modeled and operated within a virtual fuel cell vehicle. This effort resulted in the ability to assess dynamic operating parameters and interactions between the storage system and fuel cell power plant, including the evaluation of performance throughout various drive cycles. Second, we engaged in cost modeling of various incarnations of the storage systems. This analysis

  10. Origin and characteristics of yardangs in the Um Al-Rimam depressions (N Kuwait)

    NASA Astrophysics Data System (ADS)

    Al-Dousari, Ali. M.; Al-Elaj, Maraheb; Al-Enezi, Eqbal; Al-Shareeda, Abdulaziz

    2009-03-01

    Although Arabia hosts one of the largest deserts in the world, studies regarding aeolian erosional features in general and yardangs in particular are rare. The principal aim of this study is to delineate and investigate the various forms of yardangs in the Um Al-Rimam depressions in the northern part of Kuwait. The study area consists of two main depressions connected by neck area made up of continental sediments. Both depressions are surrounded by a dissected escarpment and their floors host muddy playas. On lithological bases, three main types of yardang have been identified: 7 yardangs are sculptured in sandstones of Lower Fars Formation (Lower to Middle Miocene), 23 are carved in calcretic rocks of Ghar Formation (Oligocene to Lower Miocene), and 11 yardangs are developed in Quaternary sediments. Their mean orientation NW (297°) coincides with the prevailing direction of the strong local northwesterly wind called the shamal. The average length/width ratio is 1.5:1. The wide geographic distribution of yardangs around the margins of the northern depression is due to sand blasting. This is explained by the annual sand accumulation measured in the study area where the northern depression shows 143 times higher accumulation than the southern depression, the neck area and the platform above the depressions. Also, the field measurements for annual erosional rates show that the sides of the yardangs are more affected by erosion compared to their middle parts. Remarkably slight mineralogical variations were detected within the surface sediments of Um Al-Rimam depressions and the Quaternary muddy yardangs which indicate a common origin. The age of yardangs is unknown but annual erosional rates on a small Quaternary muddy yardang suggest that they range in age between 44 and 1500 years depending on yardang size. It is believed, as indicated from field observation and interpretation of aerial photos, that the majority of yardangs are pre-existing bedrock forms. These

  11. Diagnosing resolution sensitivity over the Maritime Continent in the MetUM

    NASA Astrophysics Data System (ADS)

    Woolnough, S. J.; Bush, S. J.; Schiemann, R.; Turner, A. G.; Martin, G.

    2014-12-01

    The Maritime Continent, with over 25,000 islands ranging from hundreds to 780,000 square kilometers, is a key challenge for cumulus-convection and coastal parameterizations in climate resolution GCMs. We studied the resolution sensitivity of precipitation over the Maritime Continent in the MetUM AGCM at horizontal resolutions ranging from approximately 200 to 40 km. We found robust increases in summer precipitation over the Maritime Continent Islands and decreases in summer precipitation over the northern Maritime Continent seas, similar to the resolution sensitivity seen in other studies. These precipitation changes near the Maritime Continent can be large, exceeding 5 mm/day, and are the largest changes in tropical precipitation as resolution is increased. To explore the source of these changes, we present novel experiments to diagnose the role of increased resolution of different components of the AGCM, such as the orography, coastlines and atmospheric dynamics, in the Maritime Continent domain. Our results suggest that total orographic precipitation in the Maritime Continent domain is resolution dependent at these scales. While increased precipitation associated with the higher resolution of the mean orography (see Figure 1) is compensated for by decreasing precipitation associated with changes in the subgrid orography and its effect on parameterized drag, the total orographic precipitation is not equal across resolutions. Changes in moisture convergence, precipitation and circulation due to improved resolution of the orography then affect precipitation in the wider Indo-Pacific region.

  12. The French Muséum national d’histoire naturelle vascular plant herbarium collection dataset

    PubMed Central

    Le Bras, Gwenaël; Pignal, Marc; Jeanson, Marc L.; Muller, Serge; Aupic, Cécile; Carré, Benoît; Flament, Grégoire; Gaudeul, Myriam; Gonçalves, Claudia; Invernón, Vanessa R.; Jabbour, Florian; Lerat, Elodie; Lowry, Porter P.; Offroy, Bérangère; Pimparé, Eva Pérez; Poncy, Odile; Rouhan, Germinal; Haevermans, Thomas

    2017-01-01

    We provide a quantitative description of the French national herbarium vascular plants collection dataset. Held at the Muséum national d’histoire naturelle, Paris, it currently comprises records for 5,400,000 specimens, representing 90% of the estimated total of specimens. Ninety nine percent of the specimen entries are linked to one or more images and 16% have field-collecting information available. This major botanical collection represents the results of over three centuries of exploration and study. The sources of the collection are global, with a strong representation for France, including overseas territories, and former French colonies. The compilation of this dataset was made possible through numerous national and international projects, the most important of which was linked to the renovation of the herbarium building. The vascular plant collection is actively expanding today, hence the continuous growth exhibited by the dataset, which can be fully accessed through the GBIF portal or the MNHN database portal (available at: https://science.mnhn.fr/institution/mnhn/collection/p/item/search/form). This dataset is a major source of data for systematics, global plants macroecological studies or conservation assessments. PMID:28195585

  13. The French Muséum national d'histoire naturelle vascular plant herbarium collection dataset

    NASA Astrophysics Data System (ADS)

    Le Bras, Gwenaël; Pignal, Marc; Jeanson, Marc L.; Muller, Serge; Aupic, Cécile; Carré, Benoît; Flament, Grégoire; Gaudeul, Myriam; Gonçalves, Claudia; Invernón, Vanessa R.; Jabbour, Florian; Lerat, Elodie; Lowry, Porter P.; Offroy, Bérangère; Pimparé, Eva Pérez; Poncy, Odile; Rouhan, Germinal; Haevermans, Thomas

    2017-02-01

    We provide a quantitative description of the French national herbarium vascular plants collection dataset. Held at the Muséum national d'histoire naturelle, Paris, it currently comprises records for 5,400,000 specimens, representing 90% of the estimated total of specimens. Ninety nine percent of the specimen entries are linked to one or more images and 16% have field-collecting information available. This major botanical collection represents the results of over three centuries of exploration and study. The sources of the collection are global, with a strong representation for France, including overseas territories, and former French colonies. The compilation of this dataset was made possible through numerous national and international projects, the most important of which was linked to the renovation of the herbarium building. The vascular plant collection is actively expanding today, hence the continuous growth exhibited by the dataset, which can be fully accessed through the GBIF portal or the MNHN database portal (available at: https://science.mnhn.fr/institution/mnhn/collection/p/item/search/form). This dataset is a major source of data for systematics, global plants macroecological studies or conservation assessments.

  14. The French Muséum national d'histoire naturelle vascular plant herbarium collection dataset.

    PubMed

    Le Bras, Gwenaël; Pignal, Marc; Jeanson, Marc L; Muller, Serge; Aupic, Cécile; Carré, Benoît; Flament, Grégoire; Gaudeul, Myriam; Gonçalves, Claudia; Invernón, Vanessa R; Jabbour, Florian; Lerat, Elodie; Lowry, Porter P; Offroy, Bérangère; Pimparé, Eva Pérez; Poncy, Odile; Rouhan, Germinal; Haevermans, Thomas

    2017-02-14

    We provide a quantitative description of the French national herbarium vascular plants collection dataset. Held at the Muséum national d'histoire naturelle, Paris, it currently comprises records for 5,400,000 specimens, representing 90% of the estimated total of specimens. Ninety nine percent of the specimen entries are linked to one or more images and 16% have field-collecting information available. This major botanical collection represents the results of over three centuries of exploration and study. The sources of the collection are global, with a strong representation for France, including overseas territories, and former French colonies. The compilation of this dataset was made possible through numerous national and international projects, the most important of which was linked to the renovation of the herbarium building. The vascular plant collection is actively expanding today, hence the continuous growth exhibited by the dataset, which can be fully accessed through the GBIF portal or the MNHN database portal (available at: https://science.mnhn.fr/institution/mnhn/collection/p/item/search/form). This dataset is a major source of data for systematics, global plants macroecological studies or conservation assessments.

  15. VizieR Online Data Catalog: A dust model for bet Pic from 0.58 to 870um (Ballering+, 2016)

    NASA Astrophysics Data System (ADS)

    Ballering, N. P.; Su, K. Y. L.; Rieke, G. H.; Gaspar, A.

    2016-08-01

    β Pic was imaged with the HST/STIS CCD in coronagraphic (50CORON) mode under program GO-12551 (PI: Apai), and the results of these observations were published in Apai et al. (2015ApJ...800..136A). The instrument bandpass is set by the response of the CCD and centered at 0.58um. We searched the HST archive and found previously unpublished observations of β Pic with the WFC3 instrument in the IR channel (filter F110W at ~1.16um) from program GO-11150 (PI: Graham). The Spitzer/MIPS observations of β Pic were taken under the Spitzer Guaranteed Time Observing Program 90 (PI: M. Werner). The data at all three bands (24, 70, and 160um) are published here for the first time. Two sets of 24um observations were obtained. The first set was obtained on 2004 March 20, the second set of data was obtained on 2004 April 11. Two sets of 70um observations were obtained. The first set was obtained on 2004 April 12. The second set was obtained on 2005 April 4. Herschel/PACS 70um scan map observations of β Pic (PI G. Olofsson, observation IDs 1342186612 and 1342186613) were published by Vandenbussche et al. (2010A&A...518L.133V). We used the ALMA 870um continuum image previously published by Dent et al. (2014Sci...343.1490D). (1 data file).

  16. VizieR Online Data Catalog: 1-20um observations of Herbig-Haro objects (Molinari+ 1993)

    NASA Astrophysics Data System (ADS)

    Molinari, S.; Liseau, R.; Lorenzetti, D.

    1993-04-01

    For 58 exciting sources of Herbig-Haro objects/jets (HHES) we present a catalogue of photometric data for the infrared spectral bands JHKLMNQ (1-20 um). This catalog is based on our own observations and published information available up to May 1992. For each source, these data are presented in chronological order. In addition to the broad-band data, narrow-band N(8-13 um) photometric data are also provided. The flux calibration for each observational equipment is explicitly noted as the diaphragm sizes are used. The same kind of information for the established members of the FU Ori class is complementing the HHES catalogue. The frequency of observations and the photometric quality of the catalogued data are shortly discussed. (4 data files).

  17. OV-Wav: um novo pacote para análise multiescalar em astronomia

    NASA Astrophysics Data System (ADS)

    Pereira, D. N. E.; Rabaça, C. R.

    2003-08-01

    Wavelets e outras formas de análise multiescalar têm sido amplamente empregadas em diversas áreas do conhecimento, sendo reconhecidamente superiores a técnicas mais tradicionais, como as análises de Fourier e de Gabor, em certas aplicações. Embora a teoria dos wavelets tenha começado a ser elaborada há quase trinta anos, seu impacto no estudo de imagens astronômicas tem sido pequeno até bem recentemente. Apresentamos um conjunto de programas desenvolvidos ao longo dos últimos três anos no Observatório do Valongo/UFRJ que possibilitam aplicar essa poderosa ferramenta a problemas comuns em astronomia, como a remoção de ruído, a detecção hierárquica de fontes e a modelagem de objetos com perfis de brilho arbitrários em condições não ideais. Este pacote, desenvolvido para execução em plataforma IDL, teve sua primeira versão concluída recentemente e está sendo disponibilizado à comunidade científica de forma aberta. Mostramos também resultados de testes controlados ao quais submetemos os programas, com a sua aplicação a imagens artificiais, com resultados satisfatórios. Algumas aplicações astrofísicas foram estudadas com o uso do pacote, em caráter experimental, incluindo a análise da componente de luz difusa em grupos compactos de galáxias de Hickson e o estudo de subestruturas de nebulosas planetárias no espaço multiescalar.

  18. Project UM-HAUL: A self-unloading reusable lunar lander

    NASA Technical Reports Server (NTRS)

    1991-01-01

    The establishment of a lunar base is technologically and financially challenging. Given the necessary resources and political support, it can be done. In addition to the geopolitical obstacles, however, there are logistical problems involved in establishing such bases that can only be overcome with the acquisition of a significant transportation and communications network in the Earth-Moon spatial region. Considering the significant number of payloads that will be required in this process, the mass-specific cost of launching these payloads, and the added risk and cost of human presence in space, it is clearly desirable to automate major parts of such an operation. One very costly and time-consuming factor in this picture is the delivery of payloads to the Moon. Foreseeable payloads would include atmospheric modules, inflatable habitat kits, energy and oxygen plant elements, ground vehicles, laboratory modules, crew supplies, etc. The duration of high-risk human presence on the Moon could be greatly reduced if all such payloads were delivered to the prospective base site in advance of crew arrival. In this view, the idea of a 'Self-Unloading Reusable Lunar Lander' (SURLL) arises naturally. The general scenario depicts the lander being brought to low lunar orbit (LLO) from Earth atop a generic Orbital Transfer Vehicle (OTV). From LLO, the lander shuttles payloads down to the lunar surface, where, by means of some resident, detachable unloading device, it deploys the payloads and returns to orbit. The general goal is for the system to perform with maximum payload capability, automation, and reliability, while also minimizing environmental hazards, servicing needs, and mission costs. Our response to this demand is UM-HAUL, or the UnManned Heavy pAyload Unloader and Lander. The complete study includes a system description, along with a preliminary cost analysis and a design status assessment.

  19. Far-ultraviolet spectroscopy of the quasar UM 675 with the faint object spectrograph on the Hubble Space Telescope

    NASA Technical Reports Server (NTRS)

    Beaver, E. A.; Burbidge, E. M.; Cohen, Ross D.; Junkkarinen, Vesa T.; Lyons, Ronald W.

    1991-01-01

    To investigate the far-UV spectral properties of a QSO and to look for evidence of He I 584 A emission and absorption the Faint Object Spectrograph aboard the HST was used to observed UM 675. Light is detected down to 520 A in the object in the rest frame and limits are set to He I emission, the He I Gunn-Peterson effect at z = 2.148, and Ly-alpha absorption at z roughly 0.5.

  20. UM 625 REVISITED: MULTIWAVELENGTH STUDY OF A SEYFERT 1 GALAXY WITH A LOW-MASS BLACK HOLE

    SciTech Connect

    Jiang Ning; Dong Xiaobo; Yang Huan; Wang Junxian; Ho, Luis C. E-mail: xbdong@ustc.edu.cn

    2013-06-10

    UM 625, previously identified as a narrow-line active galactic nucleus (AGN), actually exhibits broad H{alpha} and H{beta} lines whose width and luminosity indicate a low black hole (BH) mass of 1.6 Multiplication-Sign 10{sup 6} M{sub Sun }. We present a detailed multiwavelength study of the nuclear and host galaxy properties of UM 625. Analysis of Chandra and XMM-Newton observations suggests that this system contains a heavily absorbed and intrinsically X-ray weak ({alpha}{sub ox} = -1.72) nucleus. Although not strong enough to qualify as radio loud, UM 625 does belong to a minority of low-mass AGNs detected in the radio. The broadband spectral energy distribution constrains the bolometric luminosity to L{sub bol} Almost-Equal-To (0.5-3) Multiplication-Sign 10{sup 43} erg s{sup -1} and L{sub bol}/L{sub Edd} Almost-Equal-To 0.02-0.15. A comprehensive analysis of Sloan Digital Sky Survey and Hubble Space Telescope images shows that UM 625 is a nearly face-on S0 galaxy with a prominent, relatively blue pseudobulge (Sersic index n = 1.60) that accounts for {approx}60% of the total light in the R band. The extended disk is featureless, but the central {approx}150-400 pc contains a conspicuous semi-ring of bright, blue star-forming knots, whose integrated ultraviolet luminosity suggests a star formation rate of {approx}0.3 M{sub Sun} yr{sup -1}. The mass of the central BH roughly agrees with the value predicted from its bulge velocity dispersion but is significantly lower than that expected from its bulge luminosity.

  1. VizieR Online Data Catalog: ALMA 870um obs. of HerMES galaxies (Bussmann+, 2015)

    NASA Astrophysics Data System (ADS)

    Bussmann, R. S.; Riechers, D.; Fialkov, A.; Scudder, J.; Hayward, C. C.; Cowley, W. I.; Bock, J.; Calanog, J.; Chapman, S. C.; Cooray, A.; de Bernardis, F.; Farrah, D.; Fu, H.; Gavazzi, R.; Hopwood, R.; Ivison, R. J.; Jarvis, M.; Lacey, C.; Loeb, A.; Oliver, S. J.; Perez-Fournon, I.; Rigopoulou, D.; Roseboom, I. G.; Scott, D.; Smith, A. J.; Vieira, J. D.; Wang, L.; Wardlow, J.

    2016-02-01

    ALMA 870um data were obtained during Cycle 0 from 2012 June to December (Program 2011.0.00539.S; PI: D. Riechers). Optical imaging observations (ugriz) using the Gemini Multi-Object Spectrograph-South (GMOS-S) were conducted in queue mode during the 2013B semester as part of program GS-2013B-Q-77 (PI: R. S. Bussmann). (3 data files).

  2. Design, fabrication and testing of 17um pitch 640x480 uncooled infrared focal plane array detector

    NASA Astrophysics Data System (ADS)

    Jiang, Lijun; Liu, Haitao; Chi, Jiguang; Qian, Liangshan; Pan, Feng; Liu, Xiang

    2015-10-01

    Uncooled infrared focal plane array (UIRFPA) detectors are widely used in industrial thermography cameras, night vision goggles, thermal weapon sights, as well as automotive night vision systems. To meet the market requirement for smaller pixel pitch and higher resolution, we have developed a 17um pitch 640x480 UIRFPA detector. The detector is based on amorphous silicon (a-Si) microbolometer technology, the readout integrated circuit (ROIC) is designed and manufactured with 0.35um standard CMOS technology on 8 inch wafer, the microbolometer is fabricated monolithically on the ROIC using an unique surface micromachining process developed inside the company, the fabricated detector is vacuum packaged with hermetic metal package and tested. In this paper we present the design, fabrication and testing of the 17um 640x480 detector. The design trade-off of the detector ROIC and pixel micro-bridge structure will be discussed, by comparison the calculation and simulation to the testing results. The novel surface micromachining process using silicon sacrificial layer will be presented, which is more compatible with the CMOS process than the traditional process with polyimide sacrificial layer, and resulted in good processing stability and high fabrication yield. The performance of the detector is tested, with temperature equivalent temperature difference (NETD) less than 60mK at F/1 aperture, operability better than 99.5%. The results demonstrate that the detector can meet the requirements of most thermography and night vision applications.

  3. The DecisionDx-UM Gene Expression Profile Test Provides Risk Stratification and Individualized Patient Care in Uveal Melanoma.

    PubMed

    Harbour, J William; Chen, Royce

    2013-04-09

    Uveal melanoma (UM) is the most common primary cancer of the eye and has a strong propensity for metastasis. Although there have been many recent improvements in the diagnosis and treatment of UM, and only 2-4% of patients present with detectable metastasis, up to half of patients are at risk for dying of metastatic disease. Clinicopathologic factors are not accurate enough for individualized patient care. Chromosomal alterations have been used for prognostic purposes, but the routine clinical use of these methods is limited by their susceptibility to sampling error resulting from tumor heterogeneity, limited clinical validation, lack of standardized testing platforms, and high technical failure rates. In contrast, the DecisionDx-UM gene expression profile test is a stand-alone platform which requires no other information for maximal prognostic accuracy and which circumvents many of the drawbacks of chromosomal methods through the use of a highly sensitive microfluidics, PCR-based platform that simultaneously measures the expression of 15 carefully selected genes from primary uveal melanoma samples obtained by fine needle biopsy. Low metastatic risk is reported as Class 1, and high metastatic risk as Class 2. The test allows patients to be stratified into risk categories such that high-risk patients can be offered intensive metastatic surveillance and adjuvant therapy while low-risk patients can be spared these interventions. This test is now used as part of the standard of care in many ocular oncology centers.

  4. UM-SCC-104: a new human papillomavirus-16 containing head and neck squamous cell carcinoma cell line

    PubMed Central

    Tang, Alice L.; Davis, Samantha J.; Owen, John H.; Graham, Martin P.; Czerwinski, Michael J.; Park, Jung Je; Walline, Heather; Stoerker, Jay; McHugh, Jonathan B.; Chepeha, Douglas; Bradford, Carol R.; Carey, Thomas E.; Prince, Mark E.

    2012-01-01

    BACKGROUND Few human papillomavirus (HPV)-positive head and neck squamous cell carcinoma (HNSCC) cell lines exist. We established UM-SCC-104, a new HPV(+) HNSCC cell linefrom a recurrent oral cavity tumor, and characterized it for the presence of cancer stem cells (CSC). METHODS Tumor cells were tested for biomarker expression by immunohistology and the presence of HPV was assessed by several methods. RESULTS UM-SCC-104 has a unique genotype, contains HPV-16 and expresses E6/E7. Inoculation of (Aldehyde Dehydrogenase) ALDH(+) and ALDH(−) cells in an immunocompromised mouse resulted in tumor growth from the ALDH(+) cells after 6 weeks that recapitulated the histology of the primary, while ALDH(−) cells did not produce tumors. CONCLUSIONS UM-SCC-104, a new HPV-16, CSC-containing HNSCC cell line will aid in studying recurrent HPV(+) tumors. The aggressive nature of this tumor is consistent with high uniform expression of EGFR and a functionally significant proportion of ALDH(+) CSC. PMID:22162267

  5. Genome Anatomy of Pyrenochaeta unguis-hominis UM 256, a Multidrug Resistant Strain Isolated from Skin Scraping.

    PubMed

    Toh, Yue Fen; Yew, Su Mei; Chan, Chai Ling; Na, Shiang Ling; Lee, Kok Wei; Hoh, Chee-Choong; Yee, Wai-Yan; Ng, Kee Peng; Kuan, Chee Sian

    2016-01-01

    Pyrenochaeta unguis-hominis is a rare human pathogen that causes infection in human skin and nail. P. unguis-hominis has received little attention, and thus, the basic biology and pathogenicity of this fungus is not fully understood. In this study, we performed in-depth analysis of the P. unguis-hominis UM 256 genome that was isolated from the skin scraping of a dermatitis patient. The isolate was identified to species level using a comprehensive multilocus phylogenetic analysis of the genus Pyrenochaeta. The assembled UM 256 genome has a size of 35.5 Mb and encodes 12,545 putative genes, and 0.34% of the assembled genome is predicted transposable elements. Its genomic features propose that the fungus is a heterothallic fungus that encodes a wide array of plant cell wall degrading enzymes, peptidases, and secondary metabolite biosynthetic enzymes. Antifungal drug resistance genes including MDR, CDR, and ERG11/CYP51 were identified in P. unguis-hominis UM 256, which may confer resistance to this fungus. The genome analysis of P. unguis-hominis provides an insight into molecular and genetic basis of the fungal lifestyles, understanding the unrevealed biology of antifungal resistance in this fungus.

  6. Genome Anatomy of Pyrenochaeta unguis-hominis UM 256, a Multidrug Resistant Strain Isolated from Skin Scraping

    PubMed Central

    Toh, Yue Fen; Yew, Su Mei; Chan, Chai Ling; Na, Shiang Ling; Lee, Kok Wei; Hoh, Chee-Choong; Yee, Wai-Yan; Ng, Kee Peng

    2016-01-01

    Pyrenochaeta unguis-hominis is a rare human pathogen that causes infection in human skin and nail. P. unguis-hominis has received little attention, and thus, the basic biology and pathogenicity of this fungus is not fully understood. In this study, we performed in-depth analysis of the P. unguis-hominis UM 256 genome that was isolated from the skin scraping of a dermatitis patient. The isolate was identified to species level using a comprehensive multilocus phylogenetic analysis of the genus Pyrenochaeta. The assembled UM 256 genome has a size of 35.5 Mb and encodes 12,545 putative genes, and 0.34% of the assembled genome is predicted transposable elements. Its genomic features propose that the fungus is a heterothallic fungus that encodes a wide array of plant cell wall degrading enzymes, peptidases, and secondary metabolite biosynthetic enzymes. Antifungal drug resistance genes including MDR, CDR, and ERG11/CYP51 were identified in P. unguis-hominis UM 256, which may confer resistance to this fungus. The genome analysis of P. unguis-hominis provides an insight into molecular and genetic basis of the fungal lifestyles, understanding the unrevealed biology of antifungal resistance in this fungus. PMID:27626635

  7. Elucidation of the annealing process required in the preparation of the thermoluminescence phosphor of CaSO4:Tm

    NASA Astrophysics Data System (ADS)

    Shinsho, Kiyomitsu; Watanabe, Eiji; Urushiyama, Akio

    2006-11-01

    The thermoluminescence phosphor of CaSO4:Tm was subjected to physicochemical studies. Careful thermo mass spectrometry and thermogravimetry/differential thermal analysis studies for a solid sample prepared by 200°C evaporation of a sulfuric acid medium without annealing by an extremely slow speed of temperature elevation were carried out. The data revealed, along with an initial weight loss corresponding to a small, nonstoichiometric amount of crystal water at 200°C, evidence for reaction with H2O vapor in air between 300 and 500°C and a 550°C and a subsequent release of SOx at higher temperatures until the beginning of bursting decomposition of CaSO4 bulk above 700°C. H1 NMR study revealed a broad signal at 9.9ppm, which was easily assigned to the crystal water involved. This initial solid has no thermostimulated luminescence (TL) efficiency. The first signal at 9.9ppm disappeared at 200°C. A new signal appeared at 13.1ppm by annealing from 300°C and increased significantly in intensity during annealing up to 600°C, which could be assigned to the intermediate produced by the reaction with H2O vapor in air. The intensity of this signal in turn was reduced by annealing at temperatures higher than 600°C and almost disappeared at 800°C. The solid by annealing at 700°C has the best TL efficiency. Several lines of the present physicochemical evidence suggest that the energy trap on irradiation of ionizing radiation is related to the concentration of O2- produced by the decomposition of SO42- during the annealing process in the course of the preparation of CaSO4:RE.

  8. Luminescence properties of pure and doped CaSO4 nanorods irradiated by 15 MeV e-beam

    NASA Astrophysics Data System (ADS)

    Salah, Numan; Alharbi, Najlaa D.; Enani, Mohammad A.

    2014-01-01

    Calcium sulfate (CaSO4) doped with proper activators is a highly sensitive phosphor used in different fields mainly for radiation dosimetry, lighting and display applications. In this work pure and doped nanorods of CaSO4 were produced by the co-precipitation technique. Samples from this material doped with Ag, Cu, Dy, Eu and Tb were exposed to different doses of 15 MeV e-beam and studied for their thermoluminesence (TL) and photoluminescence (PL) properties. Color center formation leading to PL emissions were investigated before and after e-beam irradiation. The samples doped with rare earths elements (i.e. Dy, Eu and Tb) were observed to have thinner nanorods than the other samples and have higher absorption in the UV region. The Ag and Tb doped samples have poor TL response to e-beam, while those activated by Cu, Dy and Eu have strong glow peaks at around 123 °C. Quite linear response curves in the whole studied exposures i.e. 0.1-100 Gy were also observed in Cu and Dy doped samples. The PL results show that pure CaSO4 nanorods have active color centers without irradiation, which could be enriched/modified by these impurities mainly rare earths and further enhanced by e-beam irradiation. Eu3+ → Eu2+ conversion is clearly observed in Eu doped sample after e-beam irradiation. These results show that these nanorods might be useful in lighting and display devices development.

  9. Thermoluminescence of nanocrystalline CaSO4: Dy for gamma dosimetry and calculation of trapping parameters using deconvolution method

    NASA Astrophysics Data System (ADS)

    Mandlik, Nandkumar; Patil, B. J.; Bhoraskar, V. N.; Sahare, P. D.; Dhole, S. D.

    2014-04-01

    Nanorods of CaSO4: Dy having diameter 20 nm and length 200 nm have been synthesized by the chemical coprecipitation method. These samples were irradiated with gamma radiation for the dose varying from 0.1 Gy to 50 kGy and their TL characteristics have been studied. TL dose response shows a linear behavior up to 5 kGy and further saturates with increase in the dose. A Computerized Glow Curve Deconvolution (CGCD) program was used for the analysis of TL glow curves. Trapping parameters for various peaks have been calculated by using CGCD program.

  10. Microwave window breakdown experiments and simulations on the UM/L-3 relativistic magnetron.

    PubMed

    Hoff, B W; Mardahl, P J; Gilgenbach, R M; Haworth, M D; French, D M; Lau, Y Y; Franzi, M

    2009-09-01

    Experiments have been performed on the UM/L-3 (6-vane, L-band) relativistic magnetron to test a new microwave window configuration designed to limit vacuum side breakdown. In the baseline case, acrylic microwave windows were mounted between three of the waveguide coupling cavities in the anode block vacuum housing and the output waveguides. Each of the six 3 cm deep coupling cavities is separated from its corresponding anode cavity by a 1.75 cm wide aperture. In the baseline case, vacuum side window breakdown was observed to initiate at single waveguide output powers close to 20 MW. In the new window configuration, three Air Force Research Laboratory-designed, vacuum-rated directional coupler waveguide segments were mounted between the coupling cavities and the microwave windows. The inclusion of the vacuum side power couplers moved the microwave windows an additional 30 cm away from the anode apertures. Additionally, the Lucite microwave windows were replaced with polycarbonate windows and the microwave window mounts were redesigned to better maintain waveguide continuity in the region around the microwave windows. No vacuum side window breakdown was observed in the new window configuration at single waveguide output powers of 120+MW (a factor of 3 increase in measured microwave pulse duration and factor of 3 increase in measured peak power over the baseline case). Simulations were performed to investigate likely causes for the window breakdown in the original configuration. Results from these simulations have shown that in the original configuration, at typical operating voltage and magnetic field ranges, electrons emitted from the anode block microwave apertures strike the windows with a mean kinetic energy of 33 keV with a standard deviation of 14 keV. Calculations performed using electron impact angle and energy data predict a first generation secondary electron yield of 65% of the primary electron population. The effects of the primary aperture electron

  11. BSSDATA - um programa otimizado para filtragem de dados em radioastronomia solar

    NASA Astrophysics Data System (ADS)

    Martinon, A. R. F.; Sawant, H. S.; Fernandes, F. C. R.; Stephany, S.; Preto, A. J.; Dobrowolski, K. M.

    2003-08-01

    A partir de 1998, entrou em operação regular no INPE, em São José dos Campos, o Brazilian Solar Spectroscope (BSS). O BSS é dedicado às observações de explosões solares decimétricas com alta resolução temporal e espectral, com a principal finalidade de investigar fenômenos associados com a liberação de energia dos "flares" solares. Entre os anos de 1999 e 2002, foram catalogadas, aproximadamente 340 explosões solares classificadas em 8 tipos distintos, de acordo com suas características morfológicas. Na análise detalhada de cada tipo, ou grupo, de explosões solares deve-se considerar a variação do fluxo do sol calmo ("background"), em função da freqüência e a variação temporal, além da complexidade das explosões e estruturas finas registradas superpostas ao fundo variável. Com o intuito de realizar tal análise foi desenvolvido o programa BSSData. Este programa, desenvolvido em linguagem C++, é constituído de várias ferramentas que auxiliam no tratamento e análise dos dados registrados pelo BSS. Neste trabalho iremos abordar as ferramentas referentes à filtragem do ruído de fundo. As rotinas do BSSData para filtragem de ruído foram testadas nos diversos grupos de explosões solares ("dots", "fibra", "lace", "patch", "spikes", "tipo III" e "zebra") alcançando um bom resultado na diminuição do ruído de fundo e obtendo, em conseqüência, dados onde o sinal torna-se mais homogêneo ressaltando as áreas onde existem explosões solares e tornando mais precisas as determinações dos parâmetros observacionais de cada explosão. Estes resultados serão apresentados e discutidos.

  12. NE VIII lambda 774 and time variable associated absorption in the QSO UM 675

    NASA Technical Reports Server (NTRS)

    Hamann, Fred; Barlow, Thomas A.; Beaver, E. A.; Burbidge, E. M.; Cohen, Ross D.; Junkkarinen, Vesa; Lyons, R.

    1995-01-01

    We discuss measurements of Ne VIII lambda 774 absorption and the time variability of other lines in the z(sub a) approximately equal z(sub e) absorption system of the z(sub e) = 2.15 QSO UM 675 (0150-203). The C IV lambda 1549 and N V 1240 doublets at z(sub a) = 2.1340 (shifted approximately 1500 km/s from z(sub e) strengthened by a factor of approximately 3 between observations by Sargent, Boksenberg and Steidel (1981 November) and our earliest measurements (1990 November and December). We have no information on changes in other z(sub a) approximately equal z(sub e) absorption lines. Continued monitoring since 1990 November shows no clear changes in any of the absorptions between approximately 1100 and 1640 A rest. The short timescale of the variability (less than or approximately equal to 2.9 yr rest) strongly suggests that the clouds are dense, compact, close to the QSO, and photoionized by the QSO continuum. If the line variability is caused by changes in the ionization, the timescale requires densities greater than approximately 4000/cu cm. Photoionization calculations place the absorbing clouds within approximately 200 pc of the continuum source. The full range of line ionizations (from Ne VIII lambda 774 to C III lambda 977) in optically thin gas (no Lyman limit) implies that the absorbing regions span a factor of more than approximately 10 in distance or approximately 100 in density. Across these regions, the total hydrogen (H I + H II) column ranges from a few times 10(exp 18)/sq cm in the low-ionization gas to approximately 10(exp 20)/sq cm where the Ne VIII doublet forms. The metallicity is roughly solar or higher, with nitrogen possibly more enhanced by factors of a few. The clouds might contribute significant line emission if they nearly envelop the QSO. The presence of highly ionized Ne VIII lambda 774 absorption near the QSO supports recent studies that link z(sub a) approximately equal to z(sub e) systems with X-ray 'wamr absorbers. We show that the

  13. NE VIII lambda 774 and time variable associated absorption in the QSO UM 675

    NASA Astrophysics Data System (ADS)

    Hamann, Fred; Barlow, Thomas A.; Beaver, E. A.; Burbidge, E. M.; Cohen, Ross D.; Junkkarinen, Vesa; Lyons, R.

    1995-04-01

    We discuss measurements of Ne VIII lambda 774 absorption and the time variability of other lines in the za approximately equal ze absorption system of the ze = 2.15 QSO UM 675 (0150-203). The C IV lambda 1549 and N V 1240 doublets at za = 2.1340 (shifted approximately 1500 km/s from ze strengthened by a factor of approximately 3 between observations by Sargent, Boksenberg and Steidel (1981 November) and our earliest measurements (1990 November and December). We have no information on changes in other za approximately equal ze absorption lines. Continued monitoring since 1990 November shows no clear changes in any of the absorptions between approximately 1100 and 1640 A rest. The short timescale of the variability (less than or approximately equal to 2.9 yr rest) strongly suggests that the clouds are dense, compact, close to the QSO, and photoionized by the QSO continuum. If the line variability is caused by changes in the ionization, the timescale requires densities greater than approximately 4000/cu cm. Photoionization calculations place the absorbing clouds within approximately 200 pc of the continuum source. The full range of line ionizations (from Ne VIII lambda 774 to C III lambda 977) in optically thin gas (no Lyman limit) implies that the absorbing regions span a factor of more than approximately 10 in distance or approximately 100 in density. Across these regions, the total hydrogen (H I + H II) column ranges from a few times 1018/sq cm in the low-ionization gas to approximately 1020/sq cm where the Ne VIII doublet forms. The metallicity is roughly solar or higher, with nitrogen possibly more enhanced by factors of a few. The clouds might contribute significant line emission if they nearly envelop the QSO. The presence of highly ionized Ne VIII lambda 774 absorption near the QSO supports recent studies that link za approximately equal to ze systems with X-ray 'wamr absorbers. We show that the Ne VIII absorbing gas would itself produce measurable warm

  14. [Malattia di Marchiafava-Bignami con coinvolgimento della corteccia frontale e insorgenza tardiva di sintomi psichiatrici resistenti: un caso clinico].

    PubMed

    Gramaglia, Carla; Feggi, Alessandro; Vecchi, Camilla; Di Marco, Sarah; Venesia, Alessandra; Delicato, Claudia; Chieppa, Nunzia; De Marchi, Fabiola; Cantello, Roberto; Zeppegno, Patrizia

    2016-01-01

    RIASSUNTO. Scopo. Descrivere il management di un paziente con malattia di Marchiafava-Bignami (MBD) associata a lesioni frontali corticali, senza sintomi specifici al primo accesso in Pronto Soccorso, e insorgenza tardiva di sintomi psichiatrici atipici. Metodi. Descriviamo il caso di un paziente di 44 anni con storia di abuso cronico di alcol, a cui è stata diagnosticata la MBD. Risultati. La risonanza magnetica ha evidenziato lesioni nello splenio e corpo del corpo calloso e lesioni bilaterali della corteccia frontale. Il paziente ha sviluppato sintomi psichiatrici atipici a insorgenza tardiva, che sono risultati essere resistenti alle terapie farmacologiche impostate. Discussione. Il caso che descriviamo sembra supportare le attuali, ma ancora scarse evidenze che descrivono il coinvolgimento corticale nella MBD, suggerendone l'associazione con una prognosi peggiore. I sintomi psichiatrici possono risultare difficili da trattare a causa della resistenza alle terapie. Conclusione. Il coinvolgimento di psichiatri, radiologi e neurologi secondo un approccio di consultazione-liaison si è dimostrato di fondamentale importanza per la diagnosi e l'impostazione della terapia adeguata al paziente.

  15. Soluble minerals in chemical evolution. I - Adsorption of 5-prime-AMP on CaSO4 - A model system

    NASA Technical Reports Server (NTRS)

    Orenberg, J. B.; Chan, S.; Calderon, J.; Lahav, N.

    1985-01-01

    The adsorption of 5-prime-AMP onto solid CaSO4-2H2O was studied in a saturated suspension as a function of pH and electrolyte concentration. The adsorption is pH-dependent and is directly correlated with the charge on the 5-prime-AMP molecule which is determined by the state of protonation of the N-1 nitrogen of the purine ring and the phosphate oxygens. It is proposed that the binding that occurs between the nucleotide and the salt is electrostatic in nature. The adsorption decreases with increasing ionic strength of the solution which means that in a fluctuating environment of wetting and drying cycles, a biomolecule similar to 5-prime-AMP could be expected to desorb during the drying phase. The results indicate that CaSO4-2H2O can serve as a concentrating surface for biomolecules. The significance of this is discussed with regard to the possible role of soluble minerals and their surfaces in a geochemical model consistent with the evolution of the earth and the origin of life.

  16. Sulforaphane retards the growth of UM-UC-3 xenographs, induces apoptosis, and reduces survivin in athymic mice.

    PubMed

    Wang, Fengqian; Shan, Yujuan

    2012-05-01

    Sulforaphane (SFN), an isothiocyanate that exists exclusively in cruciferous vegetables, may be the most promising preventive agent for bladder cancer (BC) to date. We previously observed that SFN dramatically inhibits human BC T24 cells in vitro. Our hypothesis is that SFN may attenuate BC growth. To test our hypothesis, we investigated the effect of SFN on human BC UM-UC-3 cell xenografts implanted into athymic mice. Sulforaphane extract was routinely prepared in our laboratory, and its content was measured with high-performance liquid chromatography. Athymic mice were injected subcutaneously with a UM-UC-3 cell suspension (2.0×10(6) cells/200 μL per mouse) and randomly divided into 2 groups. The positive control group was orally gavaged with water, and the treatment group was orally administered SFN from broccoli sprout (12 mg/kg body weight) for 5 weeks. At the end of the experiment, tumor tissues were harvested and processed for hematoxylin and eosin staining and immunohistochemistry. The average tumor volume decreased from 4.1±1.67 cm(3) in the positive control mice to 1.5±0.72 cm(3) in the SFN-treated mice, evidencing an inhibitory rate of 63%. The SFN extract also reduced the appearance of tumors, including karyopyknosis and angiogenesis. Sulforaphane extract induced caspase 3 and cytochrome c expression but reduced the expression of survivin. Sulforaphane extract retards the growth of UM-UC-3 xenografts in vivo, confirming its future potential in BC therapy.

  17. Community structure and activity of a highly dynamic and nutrient-limited hypersaline microbial mat in Um Alhool Sabkha, Qatar.

    PubMed

    Al-Thani, Roda; Al-Najjar, Mohammad A A; Al-Raei, Abdul Munem; Ferdelman, Tim; Thang, Nguyen M; Al Shaikh, Ismail; Al-Ansi, Mehsin; de Beer, Dirk

    2014-01-01

    The Um Alhool area in Qatar is a dynamic evaporative ecosystem that receives seawater from below as it is surrounded by sand dunes. We investigated the chemical composition, the microbial activity and biodiversity of the four main layers (L1-L4) in the photosynthetic mats. Chlorophyll a (Chl a) concentration and distribution (measured by HPLC and hyperspectral imaging, respectively), the phycocyanin distribution (scanned with hyperspectral imaging), oxygenic photosynthesis (determined by microsensor), and the abundance of photosynthetic microorganisms (from 16S and 18S rRNA sequencing) decreased with depth in the euphotic layer (L1). Incident irradiance exponentially attenuated in the same zone reaching 1% at 1.7-mm depth. Proteobacteria dominated all layers of the mat (24%-42% of the identified bacteria). Anoxygenic photosynthetic bacteria (dominated by Chloroflexus) were most abundant in the third red layer of the mat (L3), evidenced by the spectral signature of Bacteriochlorophyll as well as by sequencing. The deep, black layer (L4) was dominated by sulfate reducing bacteria belonging to the Deltaproteobacteria, which were responsible for high sulfate reduction rates (measured using 35S tracer). Members of Halobacteria were the dominant Archaea in all layers of the mat (92%-97%), whereas Nematodes were the main Eukaryotes (up to 87%). Primary productivity rates of Um Alhool mat were similar to those of other hypersaline microbial mats. However, sulfate reduction rates were relatively low, indicating that oxygenic respiration contributes more to organic material degradation than sulfate reduction, because of bioturbation. Although Um Alhool hypersaline mat is a nutrient-limited ecosystem, it is interestingly dynamic and phylogenetically highly diverse. All its components work in a highly efficient and synchronized way to compensate for the lack of nutrient supply provided during regular inundation periods.

  18. ON THE COMPACT H II GALAXY UM 408 AS SEEN BY GMOS-IFU: PHYSICAL CONDITIONS

    SciTech Connect

    Lagos, Patricio; Telles, Eduardo; Munoz-Tunon, Casiana; Tenorio-Tagle, Guillermo E-mail: etelles@on.br E-mail: rcarrasco@gemini.edu E-mail: gtt@inaoep.mx

    2009-06-15

    We present Integral Field Unit GMOS-IFU data of the compact H II galaxy UM 408, obtained at the Gemini South telescope, in order to derive the spatial distribution of emission lines and line ratios, kinematics, plasma parameters, and oxygen abundances as well the integrated properties over an area of 3''x4.''4 equivalent with {approx}750 pc x 1100 pc located in the central part of the galaxy. The starburst in this area is resolved into two giant regions of about 1.''5 and 1'' ({approx}375 and {approx}250 pc) diameter, respectively and separated 1.5-2'' ({approx}500 pc). The extinction distribution concentrate its highest values close but not coincident with the maxima of H{alpha} emission around each one of the detected regions. This indicates that the dust has been displaced from the exciting clusters by the action of their stellar winds. The ages of these two regions, estimated using H{beta} equivalent widths, suggest that they are coeval events of {approx}5 Myr with stellar masses of {approx}10{sup 4} M {sub sun}. We have also used [O III]/H{beta} and [S II]/H{alpha} ratio maps to explore the excitation mechanisms in this galaxy. Comparing the data points with theoretical diagnostic models, we found that all of them are consistent with excitation by photoionization by massive stars. The H{alpha} emission line was used to measure the radial velocity and velocity dispersion. The heliocentric radial velocity shows an apparent systemic motion where the east part of the galaxy is blueshifted, while the west part is redshifted, with a relative motion of {approx}10 km s{sup -1}. The velocity dispersion map shows supersonic values typical for extragalactic H II regions. We derived an integrated oxygen abundance of 12+log(O/H) = 7.87 summing over all spaxels in our field of view. An average value of 12+log(O/H) = 7.77 and a difference of {delta}(O/H) = 0.47 between the minimum and maximum values (7.58 {+-} 0.06-8.05 {+-} 0.04) were found, considering all data points

  19. The U. S. Geological Survey, Digital Spectral Library: Version 1 (0.2 to 3.0um)

    USGS Publications Warehouse

    Clark, Roger N.; Swayze, Gregg A.; Gallagher, Andrea J.; King, Trude V.V.; Calvin, Wendy M.

    1993-01-01

    We have developed a digital reflectance spectral library, with management and spectral analysis software. The library includes 498 spectra of 444 samples (some samples include a series of grain sizes) measured from approximately 0.2 to 3.0 um . The spectral resolution (Full Width Half Maximum) of the reflectance data is <= 4 nm in the visible (0.2-0.8 um) and <= 10 nm in the NIR (0.8-2.35 um). All spectra were corrected to absolute reflectance using an NIST Halon standard. Library management software lets users search on parameters (e.g. chemical formulae, chemical analyses, purity of samples, mineral groups, etc.) as well as spectral features. Minerals from borate, carbonate, chloride, element, halide, hydroxide, nitrate, oxide, phosphate, sulfate, sulfide, sulfosalt, and the silicate (cyclosilicate, inosilicate, nesosilicate, phyllosilicate, sorosilicate, and tectosilicate) classes are represented. X-Ray and chemical analyses are tabulated for many of the entries, and all samples have been evaluated for spectral purity. The library also contains end and intermediate members for the olivine, garnet, scapolite, montmorillonite, muscovite, jarosite, and alunite solid-solution series. We have included representative spectra of H2O ice, kerogen, ammonium-bearing minerals, rare-earth oxides, desert varnish coatings, kaolinite crystallinity series, kaolinite-smectite series, zeolite series, and an extensive evaporite series. Because of the importance of vegetation to climate-change studies we have include 17 spectra of tree leaves, bushes, and grasses. The library and software are available as a series of U.S.G.S. Open File reports. PC user software is available to convert the binary data to ascii files (a separate U.S.G.S. open file report). Additionally, a binary data files are on line at the U.S.G.S. in Denver for anonymous ftp to users on the Internet. The library search software enables a user to search on documentation parameters as well as spectral features. The

  20. Um enfoque antropológico para o ensino de astronomia no nível médio

    NASA Astrophysics Data System (ADS)

    Costa, G. B.; Jafelice, L. C.

    2003-08-01

    Há uma enorme carência de materiais didático-pedagógicos em astronomia para professores do ensino médio, sobretudo materiais que explorem também aspectos humanísticos. A origem do Universo é um bom exemplo desta constatação central. Embora tal origem teve explicações culturais diversas, os professores não têm informações sobre isso e muito menos material que trabalhe diferentes visões de mundo e treinamento que os capacite a abordá-las devidamente. Conseqüentemente o ensino de astronomia costuma ser tecnicista e dissociado do aspecto humano que alimenta o grande interesse e curiosidade que esses temas despertam. Aqui apresentamos propostas visando contribuir para reverter esse quadro e trabalhamos distintas visões de Universo: espontâneas, autóctones e científicas. Desenvolvemos práticas, materiais instrucionais e textos para viabilizar a adoção de um enfoque antropológico para o ensino de astronomia no nível médio, no qual as culturas humanística e científica sejam integradas de uma maneira contextualizada e eficaz para aquele ensino. Estas propostas foram aplicadas em um curso de treinamento para professores da rede pública de diferentes disciplinas. A receptividade dos professores à abordagem proposta e os resultados alcançados foram muito estimulantes. Destes, destacamos: produção de roteiros de atividades; desenvolvimento de práticas didático-pedagógicas específicas (e.g., encenação de mitos; dança primordial guarani; "criação" de constelações e interpretações pluriculturais; etc.); e sugestões concretas para a efetiva realização de um ensino interdisciplinar contextualizado, onde questões cosmogônicas servem de mote para iniciar tal ensino. Discutimos estes resultados e como o enfoque adotado pode instrumentalizar os professores para leituras de mundo que incluem naturalmente aspectos culturais, sociais e históricos associados aos temas estudados. (PPGECNM/UFRN; PRONEX/FINEP; NUPA/USP; Temáticos/FAPESP)

  1. Pneumatocele selar a tensión: Reporte de un caso y revisión de la literatura

    PubMed Central

    Campero, Álvaro; Ajler, Pablo; Goldschmidt, Ezequiel; Bendersky, Damián; Campero, Abraham

    2012-01-01

    Introducción: El neumoencéfalo a tensión luego de la cirugía transesfenoidal es poco común. En la literatura existen pocos casos reportados en los cuales el aire se encuentra localizado exclusivamente en las regiones selar y supraselar, constituyendo un pneumatocele selar. En este artículo se describe un caso inusual de pneumatocele selar a tensión de presentación tardía. Descripción del caso: Una mujer de 57 años consultó por hemianopsia bitemporal. Previamente, ya se le había realizado una cirugía transnasal por un adenoma hipofisario y se le había colocado una derivación lumbo-peritoneal por la presencia de una fístula de líquido cefalorraquídeo. Además, se le había realizado una resección transcraneal de un componente intracavernoso del tumor y radiocirugía debido a la agresividad del mismo. Se llevó a cabo una resonancia magnética que demostró un pneumatocele selar y supraselar. Intervención: Se realizó un abordaje transciliar. La región selar estaba encapsulada por tejido cicatrizal debido a los procedimientos previos. Se abrió la cicatriz y el aire fue evacuado. Posteriormente, el piso selar fue cerrado con grasa y cola de fibrina. Despuós del procedimiento, su campo visual retornó a la normalidad. Un año después de su última cirugía, continua asintomática. Conclusión: El pneumatocele selar y supraselar a tensión es un hallazgo extremadamente raro luego de una cirugía transesfenoidal. Su manifestaciónw clínica sería la alteración visual debida a la compresión inferior de la vía óptica. El pneumatocele selar a tensión debe ser evacuado en un corto plazo. PMID:23596554

  2. VizieR Online Data Catalog: HI and 250um images of the Virgo cirrus (Bianchi+, 2017)

    NASA Astrophysics Data System (ADS)

    Bianchi, S.; Giovanardi, C.; Smith, M. W. L.; Fritz, J.; Davies, J. I.; Haynes, M. P.; Giovanelli, R.; Baes, M.; Bocchio, M.; Boissier, S.; Boquien, M.; Boselli, A.; Casasola, V.; Clark, C. J. R.; de Looze, I.; di Serego Alighieri, S.; Grossi, M.; Jones, A. P.; Hughes, T. M.; Hunt, L. K.; Madden, S.; Magrini, L.; Pappalardo, C.; Ysard, N.; Zibetti, S.

    2016-10-01

    Images of the Virgo cirrus in the atomic gas HI emission and in the dust emission at 250um from Herschel-SPIRE. Two images are provided for HI emission from low velocity (LVC; -20km/sum: the observations, with large scale offsets removed; the model, obtained from the emissivity values derived in the paper and the two atomic gas maps; the residuals between observations and models. The three images have been obtained from observations/model/residuals for each of the four HeViCS fields, and combined in a single large scale map after removing field-to-field offsets; they are the same presented in Fig. 8 of the paper. In all cases the resolution is 4.8'. (2 data files).

  3. Um satélite brasileiro para observação do diâmetro solar

    NASA Astrophysics Data System (ADS)

    Emilio, M.; Leister, N. V.; Benevides Soares, P.; Teixeira, R.; Kuhn, J.

    2003-08-01

    Propomos uma missão espacial para medir a forma e o diâmetro solar com o objetivo de ajudar a determinar o potencial gravitacional do Sol e a sua rotação com precisão, testar modelos teóricos de variação de energia e pela primeira vez medir os modos g de oscilação. As observações serão obtidas através do instrumento denominado APT (Astrometric and Photometric Telescope) descrito por Kuhn(1983). A sensibilidade do instrumento é de 0,2 mas em 27 dias para as observações do diâmetro solar feitas a cada minuto. Esta é uma missão de três anos de duração e pode complementar as medidas que serão feitas pelo satélite PICARD (a ser lançado em 2007). Outros parâmetros físicos podem ser obtidos com as mesmas imagens o que certamente interessará à comunidade de física solar. Um primeiro contato foi realizado com a agência espacial brasileira que pretende lançar um satélite científico a cada dois anos.

  4. Um estudo espectrofotométrico da variável cataclísmica V3885 Sgr

    NASA Astrophysics Data System (ADS)

    Ribeiro, F. M. A.; Diaz, M. P.

    2003-08-01

    Variáveis Cataclísmicas são sistemas binários cerrados compostos de uma anã vermelha que transfere matéria para uma anã branca, em sistemas não magnéticos ocorre a formação de um disco de acresção em torno da anã branca. V3885 Sgr é uma variável cataclísmica classificada como sendo do tipo nova-like. É apresentado um estudo espectrofotométrico de V3885 Sgr de alta resolução temporal feito na região do visível. A região observada é centrada em Ha e abrange também a linha de HeI 6678. O primeiro resultado obtido neste estudo é a determinação do período orbital a partir de medidas da velocidade radial da linha de Ha como sendo 0,20716071(22) dias, resolvendo inconsistências quanto a esse valor na literatura e definindo uma efeméride a longo prazo para o sistema. Com este período e as medidas de velocidade radial do perfil de linha de Ha foi construído um diagrama de massas, através do qual restringimos as massas das componentes estelares do sistema e limitamos a inclinação orbital do sistema. Foram construídos diagramas de Greenstein para as linhas de Ha e HeI, onde os espectros médios em cada intervalo de fase são representados lado a lado em escala de cinza, indicando a existência de uma emissão intensa proveniente da parte posterior do disco. A partir da tomografia Doppler obtivemos perfis de emissividade radial para o disco tanto para a linha de Ha como para HeI. Os resultados obtidos são comparados com os de outros sistemas estudados com a mesma técnica. Serão apresentados também resultados da tomografia de flickering para o sistema.

  5. Mental health problems of undocumented migrants (UMs) in the Netherlands: a qualitative exploration of help-seeking behaviour and experiences with primary care

    PubMed Central

    Teunissen, Erik; Sherally, Jamilah; van den Muijsenbergh, Maria; Dowrick, Chris; van Weel-Baumgarten, Evelyn; van Weel, Chris

    2014-01-01

    Objective To explore health-seeking behaviour and experiences of undocumented migrants (UMs) in general practice in relation to mental health problems. Design Qualitative study using semistructured interviews and thematic analysis. Participants 15 UMs in the Netherlands, varying in age, gender, country of origin and education; inclusion until theoretical saturation was reached. Setting 4 cities in the Netherlands. Results UMs consider mental health problems to be directly related to their precarious living conditions. For support, they refer to friends and religion first, the general practitioner (GP) is their last resort. Barriers for seeking help include taboo on mental health problems, lack of knowledge of and trust in GPs competencies regarding mental health and general barriers in accessing healthcare as an UM (lack of knowledge of the right to access healthcare, fear of prosecution, financial constraints and practical difficulties). Once access has been gained, satisfaction with care is high. This is primarily due to the attitude of the GPs and the effectiveness of the treatment. Reasons for dissatisfaction with GP care are an experienced lack of time, lack of personal attention and absence of physical examination. Expectations of the GP vary, medication for mental health problems is not necessarily seen as a good practice. Conclusions UMs often see their precarious living conditions as an important determinant of their mental health; they do not easily seek help for mental health problems and various barriers hamper access to healthcare for them. Rather than for medication, UMs are looking for encouragement and support from their GP. We recommend that barriers experienced in seeking professional care are tackled at an institutional level as well as at the level of GP. PMID:25416057

  6. The challenge and scientific application of the CO2 4.3 um atmospheric limb emission of Mars

    NASA Astrophysics Data System (ADS)

    Lopez-Valverde, M. A.; Piccialli, A.; Giuranna, M.; Funke, B.; López-Puertas, M.; Jurado-Navarro, A. A.; García-Comas, M.; González-Galindo, F.; López-Moreno, J. J.; Jiménez-Monferrer, S.

    2015-10-01

    The atmospheric fluorescent emissions of CO2 at 4.3- um have been observed in the daytime upper atmosphere of Mars from a limb geometry by the instruments OMEGA and PFS on board Mars Express [1, 8]. Initial analysis using non-local thermodynamic equilibrium (NLTE) models show that the emissions are well understood [7, 3, 6]. Yet they have not been exploited to derive important thermospheric parameters, like CO2 densities and temperatures. Our major goals are to improve current NLTE models with a joint study of OMEGA and PFS data, and to build an ambitious state-of-the-art NLTE retreival scheme for Mars. Recent progress has been made in these directions on Mars, Venus and Earth. We will present a summary of these efforts and the difficulties and expectatives for its application to the Mars Express data

  7. Integration of geophysical and geological data for delimitation of mineralized zones in Um Naggat area, Central Eastern Desert, Egypt

    NASA Astrophysics Data System (ADS)

    Gaafar, Ibrahim

    2015-06-01

    An integrated approach for geophysical, geological and mineralogical data was followed for Um Naggat area, Central Eastern Desert, Egypt, in order to delineate its mineralized zones. The albitized granites are well-defined on the Th- and U-channel images, by their anomalous shapes, reaching 150 ppm and 90 ppm respectively, beside low K content. Interpretations of the aeromagnetic maps delineated four regional structural trends oriented due NNW, NW, ENE and E-W directions. They are identified as strike-slip faults, which coincide well with field observations, where NW-trending faults cut and displace right laterally ENE-trending older ones. The interaction between these two strike-slip fault systems confining the albite granite is easily identified on the regional data presenting longer wavelength anomalies, implying deep-seated structures. They could represent potential pathways for migration of enriched mineralized fluids. Geochemically, albite granites of peraluminous characteristics that had suffered extensive post-magmatic metasomatic reworking, resulted into development of (Zr, Hf, Nb, Ta, U, Th, Sn) and albite-enriched and greisenized granite body of about 600 m thick, and more than 3 km in strike length. The albite granite is characterized by sharp increase in average rare metal content: Zr (830 ppm), Hf (51 ppm), Nb (340 ppm), Ta (44 ppm), and U (90 ppm). Thorite, uranothorite, uraninite and zircon are the main uranium-bearing minerals of magmatic origin within the enclosing granite. However, with respect to Zr, Nb, and Ta, the albitized granite can be categorized as rare metal granite. The integration of airborne geophysical (magnetic and γ-ray spectrometric), geological, geochemical and mineralogical data succeeded in assigning the albite granite of Um Naggat pluton as a mineralized zone. This zone is characterized by its high thorium and uranium of hydrothermal origin as indicated by its low Th/U ratio, with rare metals mineralization controlled by two

  8. A rare malposition of the thoracic venous catheter introduced via the left internal jugular vein

    PubMed Central

    Ghosh, Supradip; Dewan, Himanshu; Bhattacharyya, Sandip

    2008-01-01

    A rare malposition of central venous catheter in the left superior intercostal vein is described. The diagnostic features and the possible ways to prevent this complication are discussed. PMID:19742265

  9. Implantation and Maintenance of Chronic Jugular Venous Catheters in Rhesus Monkeys (Macaca mulatta),

    DTIC Science & Technology

    1979-11-05

    ventilation. The vest was closed in back with a zipper, which was routinely secured with a safety pin . A drawstring at the waistallowed adjustable fit to the...Laboratories, Pearl River, NY). Routine flushing procedure was then resumed. Between flushings, the exposed end of the catheter was tied to a safety pin attached

  10. Successful retrieval of an irretrievable jugular tesio catheter using a fogarty arterial embolectomy catheter.

    PubMed

    Arnáiz-García, María Elena; Gutiérrez-Diez, Francisco; Arnáiz-García, Ana María; Arnáiz, Javier; Expósito, Víctor; Nistal, Juan Francisco; Rodríquez-Entem, Felipe; Olalla, Juan José; López-Rodríguez, Javier; González-Santos, José María

    2014-05-01

    Long life expectancy and wide development of therapies have increased the number of patients under artificial treatment for lost kidney function or dialysis. Different options for vascular access are suitable for receiving this therapy. The use of tunneled catheters has consequently increased complications related to its use. A difficult retrieval of catheters caused by a hard fibrin sheath along its trajectory is a common drawback. Herein, we report a woman with suspicion of hemodialysis catheter infection and an irretrievable Tesio catheter. A novel technique using a Fogarty arterial catheter allowed a successful retrieval and avoided an aggressive management.

  11. Detection of Reflux in Jugular and Vertebral Veins Through Directional Multigate Quality Doppler Profiles

    NASA Astrophysics Data System (ADS)

    Forzoni, Leonardo; Morovic, Sandra; Semplici, Paolo; Corsi, Massino; Ricci, Stefano; Tortoli, Piero

    Chronic Cerebro-Spinal Venous Insufficiency (CCSVI) is a medical condition where deoxygenated blood flows from the veins surrounding the brain and spine is slowed down or blocked in its return to the heart. The diagnosis and severity of CCSVI can be assessed by investigating the possible presence and the extent of such reflux and/or blockage in neck veins and intracranial veins, with the patient in both sitting and supine positions. During such examinations, B-Mode and Color Doppler ultrasound are not always capable of accurately detect the flow behavior in all subjects.

  12. An Investigation of the Adsorption Characteristics of 5'ATP and 5'AMP onto the Surface of Caso4 x 2H2O

    NASA Technical Reports Server (NTRS)

    Calderon, J.; Sweeney, M. A.

    1984-01-01

    A model has been proposed in which solid surfaces can act as a site for cataletic activity of condensation reactions for certain biomolecules. From this model, the adsorption characteristics of 5'ATP and 5'AMP onto the surface of CaSO4.2H2O was chosen for study. It has been proven that 5'ATP and 5'AMP do adsorb onto the surface of CaSO4. Studies were then made to determine the dependence of absorption versus time, concentration, ionic strength and pH. It was found that the adsorption of the nucleotides is highly pH dependent, primarily determined by the phosphate acid groups of the nucleic acid molecule. From this investigation, the data obtained is discussed in relation to the model for the prebiotic earth.

  13. VizieR Online Data Catalog: 70um-1.2mm and N2H+ maps of IRDC18454 (W43) (Beuther+,

    NASA Astrophysics Data System (ADS)

    Beuther, H.; Tackenberg, J.; Linz, H.; Henning, T.; Krause, O.; Ragan, S.; Nielbock, M.; Launhardt, R.; Schmiedeke, A.; Schuller, F.; Carlhoff, P.; Nguyen-Luong, Q.; Sakai, T.

    2011-11-01

    The cloud complex with a size of ~6'x6' was observed with PACS on Herschel on 2010 March 9. Maps at 250, 350, and 500um were obtained with SPIRE 2010) on 2010 March 11. We observed IRDC18454-1 with the Plateau de Bure Interferometer during five nights in October and November 2009 at 93GHz in the C and D configurations. The N2H+ data has been observed using the BEARS receiver at the NRO 45m telescope in Nobeyama, Japan. The different velocity components have been observed one in April 2010 with an average system temperature of Tsys=206K, the second in June, at slightly lower Tsys. The MIPS 24um data (from MIPSGAL) as well as the IRAC 8um observations (from GLIMPSE) are taken from the Spitzer archive. The 1.2mm continuum data were first presented in Beuther et al. (2002, Cat. J/ApJ/566/945) and the APEX 870um data are part of the ATLASGAL survey of the Galactic plane (Schuller et al., 2009A&A...504..415S). (2 data files).

  14. Technology Development for High-Efficiency Solar Cells and Modules Using Thin (<80 um) Single-Crystal Silicon Wafers Produced by Epitaxy: June 11, 2011 - April 30, 2013

    SciTech Connect

    Ravi, T. S.

    2013-05-01

    Final technical progress report of Crystal Solar subcontract NEU-31-40054-01. The objective of this 18-month program was to demonstrate the viability of high-efficiency thin (less than 80 um) monocrystalline silicon (Si) solar cells and modules with a low-cost epitaxial growth process.

  15. Descompresión microvascular en espasmo hemifacial: Reporte de 13 casos y revisión de la literatura

    PubMed Central

    Campero, Alvaro; Herreros, Isabel Cuervo-Arango; Barrenechea, Ignacio; Andjel, Germán; Ajler, Pablo; Rhoton, Albert

    2016-01-01

    Objetivo: El propósito del presente trabajo es presentar los resultados de 13 pacientes con diagnóstico de espasmo hemifacial (EHF), en los cuales se realizó una descompresión microvascular (DMV). Material y Método: Desde Junio de 2005 a Mayo de 2014, 13 pacientes con diagnóstico de EHF fueron intervenidos quirúrgicamente, realizando una DMV. Se evaluó: edad, sexo, tiempo de evolución de la sintomatología, hallazgos intraoperatorios y resultados postoperatorios. Resultados: De los 13 pacientes intervenidos, 7 fueron mujeres y 6 varones. La media de edad fue de 53 años. El tiempo medio entre el inicio de la sintomatología y la intervención quirúrgica osciló entre 3 y 9 años. En todos los casos el EHF era típico, uno de ellos con neuralgia trigeminal concomitante, observándose en todos compresión neurovascular intraoperatoria. Por orden decreciente de frecuencia la causa de la compresión fue arteria cerebelosa anteroinferior, arteria cerebelosa posteroinferior, arteria dolicomega basilar y arteria dolicomega vertebral. El seguimiento postoperatorio fue en promedio de 24 meses. El 62% presentó desaparición postquirúrgica inmediata de la sintomatología preoperatoria, el 30% desaparición tras un período de 3 semanas a 2 meses (8% con mejoría parcial), y en el 8% no hubo mejoría. En cuanto a las complicaciones postoperatorias: 3 pacientes presentaron paresia facial II-III en la escala de House-Brackman (se recuperaron en un período de 6 meses), y 1 paciente presentó fístula de líquido cefalorraquídeo. Ninguno de los pacientes de la serie presentaron hipoacusia transitorio o permanente. Conclusión: La DMV como tratamiento del EHF es un procedimiento efectivo y seguro, que permite la resolución completa de la patología en la mayoría de los casos. PMID:27127708

  16. Evaluation of high-resolution MetUM and AMPS forecasts of near-surface meteorological variables over Larsen C ice shelf and northern Antarctic Peninsula

    NASA Astrophysics Data System (ADS)

    Orr, Andrew; Kirchgaessner, Amelie; King, John; Weeks, Mark; Gadian, Alan; Kuipers Munneke, Peter; van den Broeke, Michiel; Steffen, Konrad

    2016-04-01

    High-resolution weather forecasts are an important tool for understanding the detailed patterns of surface melt on the Larsen C ice shelf (LCIS), Antarctic Peninsula. We investigate the skill of UK Met Office Unified Model (MetUM) and Antarctic Mesoscale Prediction System (AMPS) forecasts with horizontal grid spacing of 4-5 km for a 1 month period during January-February 2011 by comparing near-surface model output to automatic weather station measurements at 5 sites on the LCIS and 3 on the northern Antarctic Peninsula. Forecasts for the range 12-24 h showed a fairly homogeneous performance over the LCIS. The 2 m temperature simulated by AMPS has a correlation with observations of 0.5-0.6 and a systematic cold bias of around -1 degrees centigrade. By comparison, the MetUM had a higher correlation and was less negatively biased. The simulated surface pressure has a correlation of 0.99 and small biases in both models. AMPS yielded better results than the MetUM for 10 m wind speed, being able to capture particularly well synoptically-driven high wind speeds which the MetUM systematically underestimated. Both models struggle to simulate the 10 m wind direction when the wind conditions are highly variable. The simulation of specific humidity by both models was poor. Both models showed a general reduction in performance over the northern Antarctic Peninsula compared to the LCIS. Extending the analysis to consider the 12-36 h forecast range demonstrated a relatively weak dependence of model skill to the length of the forecast. The study focuses particularly on the representation of foehn wind events, which are an important contributor to surface melt over the LCIS, by examining additional ~1 km scale forecasts using the MetUM.

  17. The dependence of land-atmosphere interactions on atmospheric parametrizations in the JULES/UM modelling system

    NASA Astrophysics Data System (ADS)

    Johnson, Helen; Best, Martin

    2015-04-01

    It has been understood for a while now that atmospheric behaviour is affected by land surface processes, modelling this relationship however still presents challenges. Most numerical weather prediction (NWP) models couple an atmospheric model to a land surface model in order to forecast the weather and/or climate. The Global Land-Atmosphere Coupling Experiment (GLACE) demonstrated that soil moisture variability has considerable control over atmospheric behaviour, particularly impacting on precipitation and temperature variability. The study also suggested that differences in coupling strengths between models may be due to differences in atmospheric parametrizations. There have since been other studies which support this claim but it is not yet clear which parameters control the land-atmosphere coupling strength or indeed what it should be. In this study we investigate whether certain atmospheric parameters hold more control than others over model sensitivity to land surface changes. We focus on the interaction of the JULES (Joint UK Land Environment Simulator) land surface model with the Met Office Unified Model (UM) that is used for operational NWP and climate prediction. For computational efficiency we ran the UM at a single site using a single column model (SCM) rather than running a global model simulation. A site in the Sahel region of West Africa was chosen as this is an area that was identified by GLACE as being especially responsive to changes in soil moisture. JULES was run several times with various different initial soil moisture profiles to create an ensemble of surface sensible and latent heat fluxes that could be used to force a set of different SCM runs in order to simulate a range of different atmospheric conditions. Various atmospheric parameters in the SCM were then perturbed to create additional sets of SCM runs with different sensitivities to soil moisture changes. By analysing the difference in spread between the standard configuration and the

  18. Performance of thin CaSO4:Dy pellets for calibration of a Sr90+Y90 source

    NASA Astrophysics Data System (ADS)

    Oliveira, M. L.; Caldas, L. V. E.

    2007-09-01

    Because of the radionuclide long half-life, Sr90+Y90, plane or concave sources, utilized in brachytherapy, have to be calibrated initially by the manufacturer and then routinely while they are utilized. Plane applicators can be calibrated against a conventional extrapolation chamber, but concave sources, because of their geometry, should be calibrated using relative dosimeters, as thermoluminescent (TL) materials. Thin CaSO4:Dy pellets are produced at IPEN specially for beta radiation detection. Previous works showed the feasibility of this material in the dosimetry of Sr90+Y90 sources in a wide range of absorbed dose in air. The aim of this work was to study the usefulness of these pellets for the calibration of a Sr90+Y90 concave applicator. To reach this objective, a special phantom was designed and manufactured in PTFE with semi spherical geometry. Because of the dependence of the TL response on the mass of the pellet, the response of each pellet was normalized by its mass in order to reduce the dispersion on TL response. Important characteristics of this material were obtained in reference of a standard Sr90+Y90 source, and the pellets were calibrated against a plane applicator; then they were utilized to calibrate the concave applicator.

  19. The Myriapoda and Onychophora collection (MY) of the Muséum national d'Histoire naturelle (MNHN, Paris).

    PubMed

    Bras, Gwenaël Le; Geoffroy, Jean-Jacques; Albenga, Laurent; Mauriès, Jean-Paul

    2015-01-01

    The Myriapoda and Onychophora collection dataset inventories the occurrence records of the collection of myriapods and onychophorans in the Muséum national d'Histoire naturelle, Paris. The dataset currently consists of 202 lots of onychophorans, representing all of those present, and almost ten thousand (9 795) lots of myriapods, representing 33 to 40% of the MNHN Myriapoda collection. This collection, which is of key historic importance, represents the results of two centuries of myriapod and onychophoran studies. The sources of the collection are worldwide, with a high representation for metropolitan France for the myriapods. None of the occurrences are yet georeferenced. Access to the dataset via the data portals of the MNHN and the GBIF has been made possible through the e-ReColNat project (ANR-11-INBS-0004). The Myriapoda and Onychophora collection of MNHN is actively expanding, hence both the collection and dataset are in continuous growth. The dataset can be accessed through the portals of GBIF at http://www.gbif.org/dataset/3287044c-8c48-4ad6-81d4-4908071bc8db and the MNHN at http://science.mnhn.fr/institution/mnhn/collection/my/item/search/form.

  20. The Myriapoda and Onychophora collection (MY) of the Muséum national d’Histoire naturelle (MNHN, Paris)

    PubMed Central

    Bras, Gwenaël Le; Geoffroy, Jean-Jacques; Albenga, Laurent; Mauriès, Jean-Paul

    2015-01-01

    Abstract The Myriapoda and Onychophora collection dataset inventories the occurrence records of the collection of myriapods and onychophorans in the Muséum national d’Histoire naturelle, Paris. The dataset currently consists of 202 lots of onychophorans, representing all of those present, and almost ten thousand (9 795) lots of myriapods, representing 33 to 40% of the MNHN Myriapoda collection. This collection, which is of key historic importance, represents the results of two centuries of myriapod and onychophoran studies. The sources of the collection are worldwide, with a high representation for metropolitan France for the myriapods. None of the occurrences are yet georeferenced. Access to the dataset via the data portals of the MNHN and the GBIF has been made possible through the e-ReColNat project (ANR-11-INBS-0004). The Myriapoda and Onychophora collection of MNHN is actively expanding, hence both the collection and dataset are in continuous growth. The dataset can be accessed through the portals of GBIF at http://www.gbif.org/dataset/3287044c-8c48-4ad6-81d4-4908071bc8db and the MNHN at http://science.mnhn.fr/institution/mnhn/collection/my/item/search/form. PMID:26448704

  1. Calcareous benthonic foraminifera across the Cretaceous/Paleocene transition of Gebel Um El-Ghanayem, Kharga Oasis, Egypt

    NASA Astrophysics Data System (ADS)

    Orabi, Orabi H.; Khalil, Hamza M.

    2014-08-01

    The studies of benthic calcareous foraminifera of the Maastrichtian-early Paleocene Dakhla Formation in Gebel Um El-Ghanayem (Western Desert, Egypt), improve reconstruction of depositional environments of these successions. In total, 68 taxa of benthic foraminifera were identified in the studied succession. The late Maastrichtian assemblages (Zone CF3) are dominated by calcareous foraminifera with tapered tests, this tapered taxon Loxostomum applinae, Lox. tegulatum various dentalinid taxa, and Buliminella cushmani dominate in CF3 Biozone. We thus interpret these faunas as being dominated by infaunal morphogroups, suggesting a moderately eutrophic environment. Danian assemblages are characterized by abundant epifaunal trochospiral species, such as Cibicidoides abudurbensis, Cibicidoides farafraensis, and Gyroidinoides girardanus. The infaunal morphogroups make up 25-47% of fauna in the Danian, in contrast to 62-76% in the Upper Maastrichtian. This dominance of the Danian benthic foraminiferal assemblages by epifaunal or mixed epifaunal/infaunal morphogroups suggests that the food supply to the benthos was less abundant than in the latest Cretaceous. The Cretaceous/Paleocene boundary (K/Pg) is within the upper unit of the Lower Kharga Member and marked by a hiatus in at least the top of CF3 Zone of the Upper Maastrichtian to the Lower Paleocene (base Plc Zone).

  2. The Neoproterozoic Kolet Um Kharit bimodal metavolcanic rocks, south Eastern Desert, Egypt: a case of enrichment from plume interaction?

    NASA Astrophysics Data System (ADS)

    Farahat, E. S.

    2006-04-01

    Neoproterozoic metavolcanic rocks of Kolet Um Kharit (KUKh) in the southern Eastern Desert of Egypt have been traditionally regarded as a bimodal island-arc sequence. However, geological and geochemical arguments presented here make this interpretation doubtful. Geochemically, these rocks are classified into mafic (tholeiitic basalts) and felsic (high-K rhyodacites to rhyolites) groups. Both the KUKh mafic and felsic metavolcanic rocks show similar geochemical characteristics, implying a genetic link. They have comparable trace element ratios, such as Zr/Nb (27 30 vs. 20 36), Y/Nb (5.44 6.25 vs. 5.05 5.9), K/Rb (577 1164 vs. 573 937), Ba/La (4.29 25 9 vs. 11.4 16.2), Nb/Yb (1.82 2.03 vs. 1.76 1.99). Similarly both groups have parallel LREE-enriched patterns (La/YbCN=2.37 2.81 vs. 2.55 3.17); and negative Nb and Ta anomalies (Nb/Lapm=0.51 0.58 vs. 0.45 0.52 and Ta/Lapm=0.51 0.62 vs. 0.49 0.55). The observed negative Nb and Ta anomalies in the KUKh metavolcanic rocks cannot be attributed to crustal contamination or fractional crystallization. These rocks could represent either a remnant of break-up LIP or were derived from an enriched mantle source containing subduction components beneath an intraoceanic back-arc basin. The recognition of the KUKh rocks as derived from an enriched mantle source revives interest in models that involve enrichment from “plume” interaction during the evolution of the Arabian-Nubian Shield.

  3. The NEUF-DIX space project - Non-EquilibriUm Fluctuations during DIffusion in compleX liquids.

    PubMed

    Baaske, Philipp; Bataller, Henri; Braibanti, Marco; Carpineti, Marina; Cerbino, Roberto; Croccolo, Fabrizio; Donev, Aleksandar; Köhler, Werner; Ortiz de Zárate, José M; Vailati, Alberto

    2016-12-01

    Diffusion and thermal diffusion processes in a liquid mixture are accompanied by long-range non-equilibrium fluctuations, whose amplitude is orders of magnitude larger than that of equilibrium fluctuations. The mean-square amplitude of the non-equilibrium fluctuations presents a scale-free power law behavior q(-4) as a function of the wave vector q, but the divergence of the amplitude of the fluctuations at small wave vectors is prevented by the presence of gravity. In microgravity conditions the non-equilibrium fluctuations are fully developed and span all the available length scales up to the macroscopic size of the systems in the direction parallel to the applied gradient. Available theoretical models are based on linearized hydrodynamics and provide an adequate description of the statics and dynamics of the fluctuations in the presence of small temperature/concentration gradients and under stationary or quasi-stationary conditions. We describe a project aimed at the investigation of Non-EquilibriUm Fluctuations during DIffusion in compleX liquids (NEUF-DIX). The focus of the project is on the investigation in micro-gravity conditions of the non-equilibrium fluctuations in complex liquids, trying to tackle several challenging problems that emerged during the latest years, such as the theoretical predictions of Casimir-like forces induced by non-equilibrium fluctuations; the understanding of the non-equilibrium fluctuations in multi-component mixtures including a polymer, both in relation to the transport coefficients and to their behavior close to a glass transition; the understanding of the non-equilibrium fluctuations in concentrated colloidal suspensions, a problem closely related with the detection of Casimir forces; and the investigation of the development of fluctuations during transient diffusion. We envision to parallel these experiments with state-of-the-art multi-scale simulations.

  4. Remote sensing detection of gold related alteration zones in Um Rus area, Central Eastern Desert of Egypt

    NASA Astrophysics Data System (ADS)

    Amer, Reda; Kusky, Timothy; El Mezayen, Ahmed

    2012-01-01

    Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) and Phased Array L-band Synthetic Aperture Radar (PALSAR) images covering the Um Rus area in the Central Eastern Desert of Egypt were evaluated for mapping geologic structure, lithology, and gold-related alteration zones. The study area is covered by Pan-African basement rocks including gabbro and granodiorite intruded into a variable mixture of metavolcanics and metasediments. The first three principal component analyses (PCA1, PCA2, PCA3) in a Red-Green-Blue (RGB) of the visible through shortwave-infrared (VNIR + SWIR) ASTER bands enabled the discrimination between lithological units. The results show that ASTER band ratios ((2 + 4)/3, (5 + 7)/6, (7 + 9)/8) in RGB identifies the lithological units and discriminates the granodiorite very well from the adjacent rock units.The granodiorites are dissected by gold-bearing quartz veins surrounded by alteration zones. The microscopic examination of samples collected from the alteration zones shows sericitic and argillic alteration zones. The Spectral Angle Mapper (SAM) and Spectral Information Divergence (SID) supervised classification methods were applied using the reference spectra of the USGS spectral library. The results show that these classification methods are capable of mapping the alteration zones as indicated by field verification work. The PALSAR image was enhanced for fracture mapping using the second moment co-occurrence filter. Overlying extracted faults and alteration zone classification images show that the N30E and N-S fractures represent potential zones for gold exploration. It is concluded that the proposed methods can be used as a powerful tool for ore deposit exploration.

  5. The resolution sensitivity of the Asian summer monsoon and its inter-model comparison between MRI-AGCM and MetUM

    NASA Astrophysics Data System (ADS)

    Ogata, Tomomichi; Johnson, Stephanie J.; Schiemann, Reinhard; Demory, Marie-Estelle; Mizuta, Ryo; Yoshida, Kohei; Osamu Arakawa

    2017-01-01

    In this study, we compare the resolution sensitivity of the Asian Summer Monsoon (ASM) in two Atmospheric General Circulation Models (AGCMs): the MRI-AGCM and the MetUM. We analyze the MetUM at three different resolutions, N96 (approximately 200-km mesh on the equator), N216 (90-km mesh) and N512 (40-km mesh), and the MRI-AGCM at TL95 (approximately 180-km mesh on the equator), TL319 (60-km mesh), and TL959 (20-km mesh). The MRI-AGCM and the MetUM both show decreasing precipitation over the western Pacific with increasing resolution, but their precipitation responses differ over the Indian Ocean. In MRI-AGCM, a large precipitation increase appears off the equator (5-20°N). In MetUM, this off-equatorial precipitation increase is less significant and precipitation decreases over the equator. Moisture budget analysis demonstrates that a changing in moisture flux convergence at higher resolution is related to the precipitation response. Orographic effects, intra-seasonal variability and the representation of the meridional thermal gradient are explored as possible causes of the resolution sensitivity. Both high-resolution AGCMs (TL959 and N512) can represent steep topography, which anchors the rainfall pattern over south Asia and the Maritime Continent. In MRI-AGCM, representation of low pressure systems in TL959 also contributes to the rainfall pattern. Furthermore, the seasonal evolution of the meridional thermal gradient appears to be more accurate at higher resolution, particularly in the MRI-AGCM. These findings emphasize that the impact of resolution is only robust across the two AGCMs for some features of the ASM, and highlights the importance of multi-model studies of GCM resolution sensitivity.

  6. The Workload of the UMS Faculty. A Report to the Joint Chairs of the Senate Budget and Taxation Committee and the House Appropriations Committee.

    ERIC Educational Resources Information Center

    Maryland Univ. System Administration, Adelphi.

    This report provides the results of a study of faculty workloads in the University of Maryland System (UMS) during the 1994-95 academic year. It was found that 19,446 course units were taught by full-time (FT) faculty at degree-granting institutions, an increase of 158 course units from the previous year while the number of FT faculty decreased by…

  7. Thermoluminescence Response of CaF2:Mn, CaFz:Dy and CaSO4:Tm to Protons and Alpha-Particles,

    DTIC Science & Technology

    1987-06-01

    linear energy tranfer (LET), which is the average stopping power over the ion range, is also shown as it is expected that the response ratio may be LET...were used for the CaSO4 :Tm and CaF 2 :Mn powders, respectively. Small samples of the powders were spread over the heating planchet to avoid self...absorption during reading. A different procedure was required for the alphas. A relatively thick layer of powder was packed onto the heating planchet

  8. Intensity variation study of the radiation field in a mammographic system using thermoluminescent dosimeters TLD-900 (CaSO4:Dy)

    NASA Astrophysics Data System (ADS)

    Corrêa, E. L.; Silva, J. O.; Vivolo, V.; Potiens, M. P. A.; Daros, K. A. C.; Medeiros, R. B.

    2014-02-01

    This study presents the results of the intensity variation of the radiation field in a mammographic system using the thermoluminescent dosimeter TLD-900 (CaSO4:Dy). These TLDs were calibrated and characterized in an industrial X-ray system used for instruments calibration, in the energy range used in mammography. They were distributed in a matrix of 19 lines and five columns, covering an area of 18 cm×8 cm in the center of the radiation field on the clinical equipment. The results showed a variation of the intensity probably explained by the non-uniformity of the field due to the heel effect.

  9. Usina de ciências: um espaço pedagógico para aprendizagens múltiplas

    NASA Astrophysics Data System (ADS)

    Martin, V. A. F.; Poppe, P. C. R.; Orrico, A. C. P.; Pereira, M. G.

    2003-08-01

    Entendemos que o Ensino de Astronomia é especialmente apropriado para motivar os alunos e aprofundar conteúdos em diversas áreas do conhecimento, pois envolve temas ligados à Física, Matemática, Química, Computação, Tratamento de Imagens e Instrumentação de Alta Precisão, além daqueles pertinentes as áreas de Geografia, História e Antropologia. Contudo, apesar do caráter interdisciplinar que esta ciência possui, a realidade atual é que a maioria dos professores em sala de aula não foram devidamente capacitados, durante o período de formação acadêmica, para ministrar conteúdos de Astronomia nos atuais Ensinos Fundamental e Médio. Neste trabalho, discutiremos de maneira ampla, num primeiro momento, a realidade do atual ensino de ciências praticado no Estado da Bahia, apontando por dependência administrativa, o crescimento e a redução do número de escolas, da taxa de analfabetismo por faixa etária, da escolarização, do atendimento, da aprovação, reprovação e abandono, de equipamentos e laboratórios e o grau de formação dos nossos atuais professores em pleno exercício de atividade docente. Num segundo momento, discutiremos o papel do Observatório Astronômico Antares/UEFS dentro desse contexto, ou seja, suas ações implementadas ao longo dos últimos anos e em particular, o recente projeto de extensão Ensino e Difusão de Astronomia, financiado pela Fundação Vitae, que procura traduzir no lúdico, no brincar de ciências, um espaço pedagógico para aprendizagens múltiplas. Neste, o papel do professor multiplicador associado ao laboratório de kits didáticos, de fácil construção e manipulação (alguns dos quais serão mostrados), perfazem os principais veículos para o desenvolvimento de conhecimentos, atitudes, habilidades e valores que preparam os nossos alunos para a carreira técnico-científica e para sua participação crítica e criativa na Sociedade.

  10. Connecting spatial and temporal scales of tropical precipitation in observations and the MetUM-GA6

    NASA Astrophysics Data System (ADS)

    Martin, Gill M.; Klingaman, Nicholas P.; Moise, Aurel F.

    2017-01-01

    This study analyses tropical rainfall variability (on a range of temporal and spatial scales) in a set of parallel Met Office Unified Model (MetUM) simulations at a range of horizontal resolutions, which are compared with two satellite-derived rainfall datasets. We focus on the shorter scales, i.e. from the native grid and time step of the model through sub-daily to seasonal, since previous studies have paid relatively little attention to sub-daily rainfall variability and how this feeds through to longer scales. We find that the behaviour of the deep convection parametrization in this model on the native grid and time step is largely independent of the grid-box size and time step length over which it operates. There is also little difference in the rainfall variability on larger/longer spatial/temporal scales. Tropical convection in the model on the native grid/time step is spatially and temporally intermittent, producing very large rainfall amounts interspersed with grid boxes/time steps of little or no rain. In contrast, switching off the deep convection parametrization, albeit at an unrealistic resolution for resolving tropical convection, results in very persistent (for limited periods), but very sporadic, rainfall. In both cases, spatial and temporal averaging smoothes out this intermittency. On the ˜ 100 km scale, for oceanic regions, the spectra of 3-hourly and daily mean rainfall in the configurations with parametrized convection agree fairly well with those from satellite-derived rainfall estimates, while at ˜ 10-day timescales the averages are overestimated, indicating a lack of intra-seasonal variability. Over tropical land the results are more varied, but the model often underestimates the daily mean rainfall (partly as a result of a poor diurnal cycle) but still lacks variability on intra-seasonal timescales. Ultimately, such work will shed light on how uncertainties in modelling small-/short-scale processes relate to uncertainty in climate change

  11. Solar Physics Topics in High School: Analysis of a Course with Practical Activities at Dietrich Schiel Observatory. (Spanish Title: Temas de Física Solar Para Estudiantes de Escuelas Secundarias: un Análisis de un Curso con Enfoque Práctico en el Observatorio Dietrich Schiel.) Tópicos de Física Solar no Ensino Médio: Análise de um Curso com Atividades Práticas no Observatório Dietrich Schiel

    NASA Astrophysics Data System (ADS)

    Calbo Aroca, Silvia; Donizete Colombo, Pedro, Jr.; Celestino Silva, Cibelle

    2012-12-01

    algunos estudiantes sabían que un espectro puede estar formado por un prisma o red de difracción, la mayor parte de ellos desconocía la naturaleza de las líneas espectrales. A lo largo del curso, esta cuestión fue trabajada con un enfoque práctico mediante la observación del espectro solar y de las lámparas durante clases expositivas/dialogadas. Los resultados obtenidos en el curso mustran la importancia de los centros de ciencia como un apoyo en la educación formal. En este caso en particular, la Sala Solar del Observatorio Dietrich Schiel se destaca como un entorno favorable para la enseñanza de la física moderna en la escuela secundaria. Este trabalho analisa resultados obtidos em um curso sobre física solar para alunos do ensino médio promovido pelo Observatório Dietrich Schiel da USP. O curso foi elaborado pelos autores com a intenção de investigar concepções sobre o Sol, ensinar tópicos de física moderna relacionados ao Sol e conhecimentos gerais sobre o astro rei. A metodologia de coleta de dados consistiu em gravação em áudio e vídeo das aulas e das entrevistas semi-estruturadas, e respostas a questionários escritos. Os resultados mostraram que a maioria dos participantes concebeu o Sol como constituído por fogo e as manchas solares como buracos na superfície solar. Embora alguns alunos soubessem que um espectro pode ser formado por um prisma ou rede de difração, a maior parte deles desconhecia a natureza das linhas espectrais. Ao longo do curso, este tema foi trabalhado com uma abordagem prática com observação do espectro solar e de lâmpadas e em aulas expositivo-dialogadas. Os resultados obtidos no curso apontam para a importância dos centros de ciências como parceiros da educação formal. Neste caso específico, a Sala Solar do Observatório Dietrich Schiel é um ambiente propício para o ensino de física moderna no ensino médio.

  12. The ultraviolet spectrum of the gravitational lens candidate UM 425 = QSO 1120+019: Evidence for broad absorption line (BAL) structure

    NASA Technical Reports Server (NTRS)

    Michelitsianos, A. G.; Oliversen, R. J.

    1995-01-01

    The UV line profile structure of high-ionization resonance lines found with the International Ultraviolet Explorer (IUE) in the brightest of four multiply imaged sources (images-A) in the candidate gravitational lens UM 425 = QSO 1120+019 indicates broad absorption line (BAL) structure. The deep-broad trough associated with the O IV line extends to velocities approiximately -12,000 km/s, and contains disrete features that suggest multicomponent velocity structure. This structure may include contributions from C IV absorption from the early-type galaxy that is believed to lens UM 425. A strong absorption feature in the blue wing of the Lyman-alpha lambda 1216 emission line may be a Lyman alpha absorption system at a Z(sub Ly alpha) = 1.437 +/- 0.003, or it may be formed by the superposition of the broad N V lambda lambda 1238, 1242 absorption trough on the extended blue emission wing of the QSO Lyman-alpha line. We obtained a redshift of Z(sub QSO) = 1.471 +/- 0.003 from Lyman-alpha lambda 1215, consistent with the redshift found by Meylan and Djorgovski in the optical. The Lyman-alpha line appears unusally weak due to the presence of N V lambda 1240 BAL absorption. A Lyman-limit absorption system at lambda 912 was not observed in the QSO rest frame. The detection of BAL structure in the other weaker ground-state resonance lines of N II (l) and S IV (l) was not found, suggesting these lines are formed in a region that is distinct from the BAL component. Detection of BAL structure in the other fainter images in this system with Hubble Space Telescope (HST) instrumentation, similar to structure observed here in image A, could provide evidence that UM 425 is a gravitational lens.

  13. Antiscaling efficacy of CaCO3 and CaSO4 on polyethylene glycol (PEG)-modified reverse osmosis membranes in the presence of humic acid: interplay of membrane surface properties and water chemistry.

    PubMed

    Ray, Jessica R; Wong, Whitney; Jun, Young-Shin

    2017-02-15

    Mineral scaling persists in many water treatment processes. More specifically, it can significantly reduce the efficacy of aromatic polyamide (PA) membranes during reverse osmosis (RO) water treatment. Previous studies have integrated hydrophilic materials, such as polyethylene glycol (PEG), onto RO membranes to combat scaling from generally hydrophobic feed water constituents; however, there are still outstanding knowledge gaps regarding the interplay of the modified membrane surface chemistry and the water chemistry in complex RO feed waters. In this work, we have investigated the mechanisms of hydrophilic PEG-grafted PA membranes in reducing mineral scaling from calcium carbonate (CaCO3) and calcium sulfate (CaSO4) in the presence of humic acid (HA). Based on surface and solution analyses, we found that colloidal formation was significantly reduced on PA-PEG surfaces in systems without HA. When HA was introduced, CaCO3 scaling was reduced on both virgin and PA-PEG membrane surfaces; while, interestingly, synergistic PEG-HA-CaSO4 interactions increased CaSO4 colloidal formation on PA-PEG membranes. Promoted CaSO4 formation results from a high negative surface charge near the PEG-modified membrane surface when HA and SO4(2-) are present, attracting more Ca(2+) to form CaSO4. The results of this work provide new information about colloidal formation at water-membrane interfaces for designing better PEG and PEG-based scale-resistant desalination membranes.

  14. The influence of high-energy 7Li ions on the TL response and glow curve structure of CaSO4 : Dy

    NASA Astrophysics Data System (ADS)

    Salah, Numan; Sahare, P. D.

    2006-07-01

    Thermoluminescence (TL) of CaSO4 : Dy phosphor, irradiated by 48 MeV 7Li ions with different fluences in the range 1 × 109-5 × 1011 ions cm-2 has been studied. The samples from the same batch were also exposed to γ-rays from a Co60 source for comparative studies. The TL glow curve of the material, irradiated with the ion beam has a simple structure with a prominent peak at around 494 K along with three small shoulders at around 424, 592 and 662 K. The TL saturation has been observed at around the fluence 1 × 1011 ions cm-2. As the fluence is increased from 1 × 109 to 5 × 1011 ions cm-2, a shift in the peak positions towards the lower temperature side, by around 7 K was observed. However, with increasing fluence, the TL glow curve structure remains invariant with no change in the relative intensities between the 494 and 424 K peaks, while in the case of γ-irradiated samples, in contrast, the intensity ratios of these peaks increase exponentially with exposures. Theoretical analysis of the glow curves of the ion beam and γ-irradiated samples was done by the glow curve deconvolution method. The efficiency of CaSO4 : Dy to 48 MeV 7Li ions has been measured relative to γ-rays of Co60 and found to be 0.81. This result, along with the observed good linearity over a large span of fluences, shows that this phosphor is quite suitable as a dosimeter for heavy charged particles.

  15. Structural evolution and Cenozoic tectonostratigraphy of the Cairo-Suez district, north Eastern Desert of Egypt: Field-structural data from Gebel Qattamiya-Gebel Um Reheiat area

    NASA Astrophysics Data System (ADS)

    Hagag, Wael

    2016-06-01

    Detailed field mapping reveals that continental rifting is strongly deforming the Gebel Qattamiya-Gebel Um Reheiat area and the entire Cairo-Suez district, in north Eastern Desert of Egypt. Rift-related structures are predominantly represented by E to WNW, NNW and NW oriented faults. The E to WNW oriented faults are small and build up the Gebel Qattamiya en echelon fault belt, whereas the faults trending NNW and NW establish a pervasive horst and graben structural style involving some rhomb-shape horsts as Gebel Qattamiya (GQRH), Gebel Um Reheiat (GURRH) and south Gebel Um Reheiat (SGURRH). Rock units of the Eocene succession and Oligocene sediments are well exposed and highly controlled by rift-related structures. Rifting was developed through two rift-phases; initial and major ones. The initial phase (a newly recognized phase in this contribution) has been occurred in Late Eocene (Priabonian), while the main phase was prevailing during Late Oligocene-Early Miocene time and is characterized by hydrothermal veins and basaltic eruptions. Continental transtension in the Cairo-Suez district, including the study area, was probably synchronous with a major tectonic stage (Pyrenean-Atlasic movement) of continental collision between African-Arabian and Eurasian plates in Late Eocene-Oligocene time. Field investigation suggests that the transfer of displacement (slip) from the Gulf of Suez proto-rift into the E-W oriented faults ''relays'' is an important mechanism, which helps to explain the current structural framework and tectonic evolution of the Cairo-Suez district. Reactivation of such faults with right-lateral divergent wrenching with NE-SW oriented extension deformed the Cairo-Suez district with several E-W oriented en echelon fault belts (e.g. Gebel Qattamiya fault belt in the study area). Thus the Cairo-Suez district represents an accommodation or transfer zone in northeastern Egypt, intercepting the ''far-field stresses'' from the Arabian-Nubian Shield, the Red

  16. Imagens do céu ontem e hoje - um multimídia interativo de astronomia e uma nova exposição no MAST

    NASA Astrophysics Data System (ADS)

    Caretta, C. A.; Lima, F. P.; Requeijo, F.; Vieira, G. G.; Alves, F.; Valente, M. E. A.; de Almeida, R.; de Garcia, G. C.; Quixadá, A. C.

    2003-08-01

    "Imagens do Céu Ontem e Hoje" é o título de uma nova exposição que está sendo inaugurada no Museu de Astronomia e Ciências Afins (MCT), que inclui experimentos interativos, maquetes, réplicas e 8 terminais de computador com um multimídia interativo sobre Astronomia para consulta dos visitantes. O multimídia apresenta um conteúdo bastante extenso, que engloba quase todos os temas em Astronomia, consistindo numa fonte de divulgação e pesquisa para um público que vai das crianças até estudantes universitários. O conteúdo está distribuído em mais de 500 páginas de texto divididas em 4 módulos: "O Universo", "Espectroscopia", "Telescópios" e "Observando o Céu". Cada módulo é subdividido em 5 seções, em média, cada uma iniciada por uma animação que ilustra os temas a serem abordados na seção. Ao final da animação, uma lista de temas é apresentada sob o título "Saiba Mais". Para exemplificar, o módulo "O Universo" contém as seguintes seções: "O Universo visto pelo homem", "Conhecendo o Sistema Solar", "Indo além do Sistema Solar", "Nossa Galáxia, a Via-Láctea" e "Indo mais além, a imensidão do Universo". A seção "Conhecendo o Sistema Solar", por sua vez, tem os seguintes temas: "A origem do Sistema Solar", "O Sol", "Os planetas", "Satélites, asteróides, cometas e outros bichos..." e "O Sistema Solar em números". Cada texto é repleto de imagens, quadros, desenhos, esquemas, etc, além de passatempos ao final de cada seção, incluindo jogos interativos, quadrinhos e curiosidades, que auxiliam o aprendizado de forma divertida. Apresentamos neste trabalho as idéias gerais que permearam a produção da exposição, e uma viagem pelo multimídia para exemplificar sua estrutura e conteúdo. O multimídia será posteriormente disponibilizado para o público externo pela página eletrônica do MAst e/ou por intermédio de uma publicação comercial.

  17. Uma Visão do Universo Segundo um Grupo de Alunos do Ensino Médio de São Paulo

    NASA Astrophysics Data System (ADS)

    Elias, D. S.; Araújo, M.; Amaral, L. H.; Voelzke, M. R.; Araújo, M.

    2005-08-01

    A astronomia, embora seja uma ciência popular, com inúmeras descobertas de interesse público, ainda é apresentada desconsiderando-se os aspectos históricos e científicos relacionados ao seu desenvolvimento, sendo geralmente veiculada nos meios de comunicação de maneira pouco esclarecedora e não raro com imprecisões. Neste trabalho analisou-se a concepção de um grupo de estudantes de Ensino Médio sobre conceitos de astronomia, visando identificar sua visão de mundo a respeito do Universo, envolvendo idéias sobre espaço e tempo. Para issso, foi aplicado um questionário em três escolas da grande São Paulo em um espaço amostral de 270 alunos. Constatou-se que, embora o ensino de astronomia esteja previsto nos PCNEM, os resultados obtidos na pesquisa mostram que há grande deficiência no conhecimento dos temas investigados. Nesse sentido, verificou-se que apenas 20% dos alunos eram capazes de relacionar a sucessão das semanas com as fases da lua, enquanto 28% associaram as estações do ano à inclinação do eixo de rotação da Terra. Por outro lado, somente 23% dos alunos tinham noções das distâncias entre os objetos celestes próximos da Terra e 56% conseguiram relacionar o Big Bang com a origem do Universo. Finalmente, constatou-se que 37% reconheciam o ano-luz como uma unidade de distância e 60% reconheciam o Sol como sendo uma estrela. Apesar de 60% dos alunos indicarem que a escola é a principal fonte para aquisição dos conhecimentos de astronomia, conclui-se que seus conceitos nessa área ainda são inadequados, havendo necessidade de ampliação e aprimoramento da abordagem desses conteúdos nos ambientes escolares.

  18. Spitzer And Herschel-based Seds Of 24um-bright z 0.3- 3.0 Starbursts And Obscured Quasars

    NASA Astrophysics Data System (ADS)

    Sajina, Anna; Yan, L.; Fadda, D.; Dasyra, K.; Huynh, M.

    2012-05-01

    A key legacy of Spitzer are the mid-IR spectra of high-redshift objects - which would not be available again until the JWST. Such spectra have been very useful for disentangling the contribution of AGN and star-formation to the observed dust emission. We have constructed a unique Spitzer mid-IR spectroscopic, nearly 24um flux-limited sample, of 191 sources at z 0.3-2.8 and with log(L_IR/L_sun) 11-13. The size and selection of the sample, allows us to study galaxy evolution from the perspective of the mid-IR where AGN are prominent. Indeed, mid-IR diagnostics suggest that 70% of our sample is AGN-dominated. Without far-IR data however, it is unclear to what degree this conclusion applies to the overall IR emission. Here we extend the earlier mid-IR studies to incorporate Herschel far-IR photometry and address the full IR SED of Spitzer 24um-selected galaxies. This allows for the overall AGN contribution to their power output to be estimated. This also allows for a direct comparison with other populations both locally and at high redshifts - ultimately placing the 24um-bright populations in the wider context of galaxy evolution. Our first conclusion is that indeed mid-IR studies alone underestimate the level of star-formation in these systems -- we now find that only 19% of the sample are AGN-dominated (i.e. where the AGN luminosity is at least 50% of the total L_IR). We also find that sources of comparable L_IR locally, are not good analogs to the our sources -- consistent for example with recent ideas of cold gas accretion vs. mergers as a means of triggering extreme starbursts. Since local sources are not good analogs to high redshift ones, we construct a set of IR SEDs templates for high redshift starbursts and obscured quasars. The templates are public and useful, among others, for interpreting the all-sky mid-IR data from WISE.

  19. An Enhancement of 160um-derived Star-Formation Rates in Active Galaxies to z = 3.2 with the ZFOURGE Survey

    NASA Astrophysics Data System (ADS)

    Cowley, Michael; Spitler, L.

    2016-08-01

    ZFOURGE is a new imaging survey, which employs unique near-infrared medium- band filters designed to probe galaxy properties over the last 12 billion years. By supplementing the high-quality ZFOURGE galaxy catalogues with data in radio, X- ray, and infrared wavebands, we have studied the complex interplay between AGNs and their host galaxies to a time when the Universe was only 10-15% of its present age. I will report on our study to compare the 160-um derived star-formation rates in active and non-active galaxies and show that AGN hosts, over all redshifts, tend to exhibit an elevated average star-formation activity compared to their non-active counterparts.

  20. Um Projeto de Intervenção nos Espaços de Exposições do Planetário do Parque do Ibirapuera

    NASA Astrophysics Data System (ADS)

    Elias, D. S.; Amaral, L. H.; de Araújo, C. F., Jr.; Matsuura, O. T.; Voelzke, M. R.

    2005-08-01

    Cada vez mais a humanidade, em sua imensa maioria, está alheia às próprias conquistas. A insatisfação com esta realidade tem levado muitos pesquisadores, instituições, empresas e governos a procurar formas alternativas de acompanhar e transmitir todo este acervo científico cultural à sociedade, buscando a melhoria da qualidade da divulgação científica e contribuindo para o processo de cultura e alfabetização científica. Não há tempo nem espaço nos limitados planos curriculares do ensino médio e mesmo nos programas de ensino que propiciem a cultura científica e o acompanhamento do vertiginoso progresso científico e tecnológico atual. Neste sentido, a educação formal escolar precisa ser complementada ou acrescida de uma educação informal, extra-escolar, que possa oferecer à sociedade o que a escola não pode oferecer. A interação do público com museus, feiras de ciências, planetários, exposições científicas e/ou culturais é de grande importância para a aquisição e difusão de conhecimentos relacionados ao mundo científico. Reconhecidamente como um modelo de alfabetização científica esses ambientes promovem uma interação social capaz de propiciar de forma efetiva uma melhor relação ensino-aprendizagem com o público. Partindo desta realidade a Universidade Cruzeiro do Sul e a Escola Municipal de Astronomia (EMA) vêm desenvolvendo um projeto de intervenção no espaço em torno do Planetário do Parque do Ibirapuera com o objetivo de se implantar um ambiente de aprendizagem motivador e desafiador que promova a popularização de conteúdos relacionados à astronomia, astrofísica e cosmologia. Busca-se, também, a aproximação e interação do público com exposições que estão sendo implementadas no planetário. Considerando que se trata de um projeto de mestrado em fase inicial o objetivo do presente trabalho é apresentar a concepção básica e os critérios que estão sendo utilizados do ponto de vista pedag

  1. An investigation of the adsorption characteristics of 5 prime ATP and 5 prime AMP onto the surface of CaSO sub 4 x 2H sub 2 O

    NASA Technical Reports Server (NTRS)

    Calderon, J.; Sweeney, M. A.

    1986-01-01

    A model has been proposed (Lahev and Chans, 1982) in which solid surfaces can act as a site for catalytic activity of condensation reactions for certain biomolecules. From this model, the adsorption characteristics of 5'ATP and 5'AMP onto the surface of CaSO4 2H2O was chosen for study. It has been proven that 5'ATP and 5'AMP do adsorb onto the surface of CaSO4. Studies were then made to determine the dependence of adsorption versus time, concentration, ionic strength and pH. It was found that the adsorption of the nucleotides is highly pH dependent, primarily determined by the phosphate acid groups of the nucleic acid molecule. From this investigation, the data obtained are discussed in relation to the model for the prebiotic earth.

  2. Aspergilosis cervical con diseminación al sistema nervioso central. Presentación de un caso y revisión de bibliografía

    PubMed Central

    Vergara, Guillermo Enrique; Roura, Natalia; del Castillo, Marcelo; Mora, Andrea; Alcorta, Santiago Condomi; Mormandi, Rubén; Cervio, Andrés; Salvat, Jorge

    2015-01-01

    Introducción: la Aspergilosis Invasiva (AI) del Sistema Nervioso Central (SNC) es infrecuente y ocurre generalmente en pacientes inmunocomprometidos. Puede presentarse con cuadros de meningitis, aneurismas micóticos, infartos o abscesos. Es una infección con pronóstico reservado y puede afectar el SNC de forma primaria o secundaria a partir de un foco que se disemina por vía hematógena. Presentamos el caso de un paciente con AI con invasión primaria a nivel óseo y diseminación posterior al cerebro. Caso clínico: Paciente masculino de 25 años con diagnóstico de leucemia linfática aguda en tratamiento quimioterápico que presentó neumonitis por metotrexate por lo que inicia tratamiento con corticoides. Posteriormente agregó cervicalgia y con el diagnóstico de osteomielitis cervical se realiza punción bajo tomografía computada (TC) sin aislarse gérmenes. Se colocó Halo Vest e inició tratamiento antibiótico empírico. Posteriormente presentó afasia de expresión secundaria a lesión frontal izquierda. Se realizó evacuación de absceso cerebral aislando A. fumigatus. El tratamiento antibiótico específico posterior permitió una buena respuesta clínica y radiológica. Conclusión: La presencia de lesiones en el SNC de pacientes inmunocomprometidos debe incluir a las micosis como diagnóstico diferencial. La evacuación quirúrgica permite llegar rápidamente al diagnóstico mejorando la respuesta posterior al tratamiento antibiótico. Para evaluar la respuesta terapéutica y posibles recaídas se debe realizar un seguimiento periódico clínico radiológico. Palabras clave: Aspergilosis cerebral; Aspergilosis cervical; Aspergilosis invasiva; Voriconazol. PMID:26600985

  3. Determination of self attenuation coefficient and relative TL efficiency of CaSO 4 :Dy, LiF:Mg,Cu,P and LiF:Mg,Ti TLDs - An alternate approach

    NASA Astrophysics Data System (ADS)

    Bakshi, A. K.; Chatterjee, S.; Palani Selvam, T.; Joshi, V. J.; Chougaonkar, M. P.

    2011-10-01

    Self attenuation of TL and relative TL efficiency of polytetra fluoro ethylene (PTFE) embedded CaSO 4:Dy disc, LiF:Mg,Ti (MTS) disc and LiF:Mg,Cu,P (MCP-N) chip were determined in the present study for photons of energy 10-34 keV. The relative TL efficiency was determined using an alternative approach in which ratio of experimental response and corrected theoretical response was used instead of measuring the absolute TL emission in photon counting mode. For CaSO 4:Dy disc, it was found that with increasing the proportion of CaSO 4:Dy phosphor in the disc, the light attenuation coefficient increases. The light attenuation coefficient of MTS disc and MCP-N chip was found to be 23.4 and 45.5 cm -1, respectively. The relative TL efficiency in the photon energy range of 10-34 keV for MTS discs and MCP-N chips, evaluated in the present study matches well with the reported values in the literature.

  4. Jugular Foramen Collision Tumor (Schwannoma and Plasma Cell Pseudotumor), a Probable IgG4-Related Disease: A Case Report.

    PubMed

    Bakhit, Mudathir S; Fujii, Masazumi; Jinguji, Shinya; Sato, Taku; Sakuma, Jun; Saito, Kiyoshi

    2017-04-06

    Lower cranial nerve sheath tumors are relatively rare, and cases of schwannoma collision tumors have rarely been reported, with most of the reported cases describing schwannoma and meningioma collision tumors. We report a very rare case of a cerebellopontine angle collision tumor of the 9(th) cranial nerve schwannoma with an IgG4 plasma cell pseudotumor. IgG4 plasma cell pseudotumors comprise a group of diseases called IgG4-related diseases (IgG4-RDs). These diseases usually affect organs such as the pancreas and salivary gland. Few cases of nervous system IgG4-RDs have been reported. Under intraoperative microscopy, the tumor in our case did not appear different from usual cases of schwannoma, but histopathology showed significant infiltration of IgG4 plasma cells. IgG4-RDs have a distinctive histopathological pattern; however, their pathophysiology remains unclear. Special attention must be paid to the diagnosis of such diseases because they mimic other diseases and can be missed.

  5. A Surgical Procedure for the Chronic Cannulation of the Carotid Artery and the Jugular Vein in Dogs,

    DTIC Science & Technology

    1986-05-01

    neck incision was closed with 3/0 chromic interrupted suture for the fascia and the subcutaneous layers, and 3/0 Prolene (Ethicon Sutures Limited...Peterborough) subcuticular for the skin. The back incision was closed with 3/0 Prolene subcuticular. Cannulae were wrapped in adhesive tape in a butterfly...fashion (about 2x3 cm) and the wings were anchored to the skin with 3/0 Prolene . The jacket (described below) was put on the dog and the cannulae

  6. Brain tissue fragments in jugular vein blood of cattle stunned by use of penetrating or nonpenetrating captive bolt guns.

    PubMed

    Coore, R R; Love, S; McKinstry, J L; Weaver, H R; Philips, A; Hillman, T; Hiles, M; Helps, C R; Anil, M H

    2005-04-01

    Although the incidence of bovine spongiform encephalopathy in cattle continues to decline in the United Kingdom, it remains important to maintain vigilance of all potential routes of transmission of infection to humans. Initial studies have demonstrated a potential risk of carcass contamination with brain tissue following the use of captive bolt gun stunning in cattle. The objective of this study was to further explore these initial findings particularly in regard to captive bolt guns currently in use in the United Kingdom. Brain tissue fragments or elevated levels of a marker protein for brain tissue were detected in venous blood samples from 4% (95% confidence interval, 1.6 to 9.8%) of cattle stunned by penetrating captive bolt gun and from 2% (95% confidence interval, 0.6 to 7%) of those stunned by nonpenetrating captive bolt gun.

  7. Gypsum (CaSO4·2H2O) Scaling on Polybenzimidazole and Cellulose Acetate Hollow Fiber Membranes under Forward Osmosis

    PubMed Central

    Chen, Si Cong; Su, Jincai; Fu, Feng-Jiang; Mi, Baoxia; Chung, Tai-Shung

    2013-01-01

    We have examined the gypsum (CaSO4·2H2O) scaling phenomena on membranes with different physicochemical properties in forward osmosis (FO) processes. Three hollow fiber membranes made of (1) cellulose acetate (CA), (2) polybenzimidazole (PBI)/polyethersulfone (PES) and (3) PBI-polyhedral oligomeric silsesquioxane (POSS)/polyacrylonitrile (PAN) were studied. For the first time in FO processes, we have found that surface ionic interactions dominate gypsum scaling on the membrane surface. A 70% flux reduction was observed on negatively charged CA and PBI membrane surfaces, due to strong attractive forces. The PBI membrane surface also showed a slightly positive charge at a low pH value of 3 and exhibited a 30% flux reduction. The atomic force microscopy (AFM) force measurements confirmed a strong repulsive force between gypsum and PBI at a pH value of 3. The newly developed PBI-POSS/PAN membrane had ridge morphology and a contact angle of 51.42° ± 14.85° after the addition of hydrophilic POSS nanoparticles and 3 min thermal treatment at 95 °C. Minimal scaling and an only 1.3% flux reduction were observed at a pH value of 3. Such a ridge structure may reduce scaling by not providing a locally flat surface to the crystallite at a pH value of 3; thus, gypsum would be easily washed away from the surface. PMID:24957062

  8. Shock induced reaction in Chicxulub target materials (CaSO4 and SiO2) and their relation to extinctions

    NASA Astrophysics Data System (ADS)

    Chen, Guangqing; Ahrens, Thomas J.

    1993-03-01

    The global platinum element rich layer, the presence of shocked quartz grains (in some cases with stishovite), and the observation of a tektite-rich layer, precisely at the K-T boundary, are the three major arguments for the extinction bolide impact hypothesis of Alvarez et al. Tektites (spherules) from Beloc in Haiti and Mimbral in Mexico received particular interest because of their geological proximity to the Chicxulub impact structure, which is a leading candidate for at least one of the K-T impact craters. Although in most localities the original glass has weathered to clay minerals, some shock-induced glass is found in outcrops and drill cores which is used for Ar-38/Ar-39 dating. The glassy tektites were found to be chemically similar and coeval at 65.0 Ma with Chicxulub melt rock. Two kinds of K-T spherules were discovered: (1) a silic black glass; and (2) a yellow glass, enriched in Ca, Mg, and S. The high sulfur content of the glass and the abundance of anhydrite (CaSO4) in the carbonate-evaporite sequence observed in Drill Holes Y-1 and Y-2 at Chicxulub prompted studies of calcium sulfate devolatization. Further discussion of our experiments is presented.

  9. Development of a technique for improving coefficient of variation of CaSO4:Dy teflon-based TLD personnel monitoring system in low-dose region.

    PubMed

    Pradhan, S M; Sneha, C; Sahai, M K; Chougaonkar, M P; Babu, D A R

    2015-12-01

    In view of the importance of zero-dose background (null signal) in influencing the coefficient of variation in low-dose region, a technique for the estimation of the same from composite (gross) signal is developed for CaSO4:Dy-based personnel monitoring system being used in India. The technique is based on simple analysis of glow curves (GCs) of unexposed and exposed dosemeters, evolution of trend/model for the zero-dose curves, generation of simulation protocol for individual zero-dose curves, establishment of characteristics of GCs of exposed dosemeters and finally preparation of an algorithm to segregate the components from composite signal. The technique offers the separation of real-time background and gives superior results over other method of approximation of the background. The results also prove efficiency of the empirical trending and simulation protocol of background GCs. The proposed technique can be implemented in routine monitoring without any extra man hours and reader time.

  10. Descompresión microvascular en neuralgia del trigémino: Reporte de 36 casos y revisión de la literatura

    PubMed Central

    Campero, Alvaro; Ajler, Pablo; Campero, Abraham Agustín

    2014-01-01

    Objetivo: El propósito del presente trabajo es presentar los resultados de 36 pacientes con diagnóstico de neuralgia del trigémino (NT), en los cuales se realizó una descompresión microvascular (DMV). Material y Método: Desde junio de 2005 a mayo de 2012, 36 pacientes con diagnóstico de NT fueron operados por el primer autor (AC), realizando una DMV. Se evaluó: Edad, sexo, tiempo de sintomatología previo a la cirugía, hallazgos intraoperatorios (a través de los videos quirúrgicos), y resultados postoperatorios. Resultados: De los 36 pacientes operados, 25 fueron mujeres y 11 varones. El promedio de edad fue de 48 años. El seguimiento postoperatorio fue en promedio de 38 meses. De los 36 pacientes, 32 (88%) evolucionaron sin dolor hasta la fecha. De los 4 casos con recurrencia de dolor, en dos pacientes se observó como hallazgo intraoperatorio un conflicto venoso. Conclusión: La DMV como tratamiento de la NT es un procedimiento efectivo y seguro. El hallazgo intraoperatorio de una “compresión” venosa podría indicar una evolución postoperatoria desfavorable. PMID:25379343

  11. Thermoluminescence, ESR and x-ray diffraction studies of CaSO4 : Dy phosphor subjected to post preparation high temperature thermal treatment

    NASA Astrophysics Data System (ADS)

    Bakshi, A. K.; Patwe, S. J.; Bhide, M. K.; Sanyal, B.; Natarajan, V.; Tyagi, A. K.; Kher, R. K.

    2008-01-01

    Thermoluminescence (TL), electron spin resonance (ESR) and x ray diffraction studies of CaSO4 : Dy phosphor subjected to post preparation high temperature treatment were carried out. Analysis of the TL glow curve indicated that the dosimetric glow peak at 240 °C reduces, whereas the low temperature satellite peak increases with the increase in the annealing temperature in the range 650-1000 °C. The influence of the annealing atmosphere on the TL glow curve structure was also observed. Reduction of the photoluminescence intensity of the annealed phosphor indicated that the environment of Dy3+ ions might have undergone some change due to high temperature treatment. Reduction in the ESR signal intensity corresponding to O_{3}^{-} and SO_{3}^{-} radicals was observed initially with the increase in the annealing temperaure; subsequently their intensity increased with temperature. Signals due to the SO_{4}^{-} radical vanished, when the phosphor was annealed beyond 800 °C. A signal corresponding to SH2- radicals was also observed in the ESR spectra for samples subjected to annealing in the temperature regime 800-1000 °C. XRD of the in situ annealed phosphor showed a change in the unit cell parameters. An endothermic peak at 860 °C in the DTA spectrum was observed.

  12. Gypsum (CaSO4·2H2O) Scaling on Polybenzimidazole and Cellulose Acetate Hollow Fiber Membranes under Forward Osmosis.

    PubMed

    Chen, Si Cong; Su, Jincai; Fu, Feng-Jiang; Mi, Baoxia; Chung, Tai-Shung

    2013-11-08

    We have examined the gypsum (CaSO4·2H2O) scaling phenomena on membranes with different physicochemical properties in forward osmosis (FO) processes. Three hollow fiber membranes made of (1) cellulose acetate (CA), (2) polybenzimidazole (PBI)/polyethersulfone (PES) and (3) PBI-polyhedral oligomeric silsesquioxane (POSS)/polyacrylonitrile (PAN) were studied. For the first time in FO processes, we have found that surface ionic interactions dominate gypsum scaling on the membrane surface. A 70% flux reduction was observed on negatively charged CA and PBI membrane surfaces, due to strong attractive forces. The PBI membrane surface also showed a slightly positive charge at a low pH value of 3 and exhibited a 30% flux reduction. The atomic force microscopy (AFM) force measurements confirmed a strong repulsive force between gypsum and PBI at a pH value of 3. The newly developed PBI-POSS/PAN membrane had ridge morphology and a contact angle of 51.42° ± 14.85° after the addition of hydrophilic POSS nanoparticles and 3 min thermal treatment at 95 °C. Minimal scaling and an only 1.3% flux reduction were observed at a pH value of 3. Such a ridge structure may reduce scaling by not providing a locally flat surface to the crystallite at a pH value of 3; thus, gypsum would be easily washed away from the surface.

  13. Otimização de procedimento de manobra para indução de reentrada de um satélite retornável

    NASA Astrophysics Data System (ADS)

    Schulz, W.; Suarez, M.

    2003-08-01

    Veículos espaciais que retornam à Terra passam por regimes de velocidade e condições de vôo distintos. Estas diferenças dificultam sua concepção aerodinâmica e o planejamento de seu retorno. A partir de uma proposta de um veículo orbital retornável (satélite SARA, em desenvolvimento no IAE/CTA) para realização de experimentos científicos e tecnológicos em ambiente de baixa gravidade, surge a necessidade de realizarem-se estudos considerando-se os aspectos relativos à sua aerodinâmica. Após o lançamento, o veículo deve permanecer em órbita pelo tempo necessário para a condução de experimentos, sendo depois direcionado à Terra e recuperado em solo. A concepção aerodinâmica é de importância para o vôo em suas diversas fases e deve considerar aspectos relativos à estabilização Aerodinâmica e ao arrasto atmosférico, sendo este último de importância crucial na análise do aquecimento a ser enfrentado. A manobra de retorno inclui considerações sobre as condições atmosféricas e dinâmica de reentrada, devendo ser calculada de forma mais precisa possível. O trabalho proposto avalia estudos da dinâmica de vôo de um satélite recuperável considerando aspectos relativos à determinação orbital com GPS, técnica utilizada com sucesso na CONAE, e seu comportamento aerodinâmico em vôo balístico de retorno, com ênfase em sua fase de reentrada atmosférica. Busca-se otimizar a manobra de reentrada de tal forma que a utilização do sistema GPS garanta minimizar a área de impacto com o solo.

  14. The genus Aphidura (Hemiptera, Aphididae) in the collection of the Muséum national d’Histoire naturelle of Paris, with six new species

    PubMed Central

    Nieto Nafría, Juan-Manuel; Mier Durante, Milagros-Pilar; Remaudière, Georges

    2013-01-01

    Abstract Specimens were studied of 65 samples of the genus Aphidura (Aphididae, Aphidinae, Macrosiphini) from the collection of the Muséum national d’Histoire naturelle (Paris). The possible synonymies of three pairs of species are discussed. New aphid host plant relationships are reported for Aphidura bozhkoae, Aphidura delmasi, Aphidura ornata, Aphidura pannonica and Aphidura picta; this last species is recorded for first time from Afghanistan. The record of Aphidura pujoli from Pakistan is refuted. The fundatrices, oviparous females and males of Aphidura delmasi are described. Six new species are established: Aphidura gallica sp. n. and Aphidura amphorosiphon sp. n. from specimens caught on species of Silene (Caryophyllaceae) from France and Iran, respectively, Aphidura pakistanensis sp. n., Aphidura graeca sp. n. and Aphidura urmiensis sp. n. from specimens caught on species of Dianthus, Gypsophila and Spergula (Caryophyllaceae) from Pakistan, Greece and Iran, respectively, and Aphidura iranensis sp. n. from specimens caught on Prunus sp. from Iran. Modifications are made to the keys by Blackman and Eastop to aphids living on Dianthus, Gypsophyla, Silene, Spergula and Prinsepia and Prunus (Rosaceae). An identification key to apterous viviparous females of species of Aphidura is also provided. PMID:23950674

  15. The genus Aphidura (Hemiptera, Aphididae) in the collection of the Muséum national d'Histoire naturelle of Paris, with six new species.

    PubMed

    Nieto Nafría, Juan-Manuel; Mier Durante, Milagros-Pilar; Remaudière, Georges

    2013-01-01

    Specimens were studied of 65 samples of the genus Aphidura (Aphididae, Aphidinae, Macrosiphini) from the collection of the Muséum national d'Histoire naturelle (Paris). The possible synonymies of three pairs of species are discussed. New aphid host plant relationships are reported for Aphidura bozhkoae, Aphidura delmasi, Aphidura ornata, Aphidura pannonica and Aphidura picta; this last species is recorded for first time from Afghanistan. The record of Aphidura pujoli from Pakistan is refuted. The fundatrices, oviparous females and males of Aphidura delmasi are described. Six new species are established: Aphidura gallica sp. n. and Aphidura amphorosiphon sp. n. from specimens caught on species of Silene (Caryophyllaceae) from France and Iran, respectively, Aphidura pakistanensis sp. n., Aphidura graeca sp. n. and Aphidura urmiensis sp. n. from specimens caught on species of Dianthus, Gypsophila and Spergula (Caryophyllaceae) from Pakistan, Greece and Iran, respectively, and Aphidura iranensis sp. n. from specimens caught on Prunus sp. from Iran. Modifications are made to the keys by Blackman and Eastop to aphids living on Dianthus, Gypsophyla, Silene, Spergula and Prinsepia and Prunus (Rosaceae). An identification key to apterous viviparous females of species of Aphidura is also provided.

  16. Project UM-HAUL (UnManned Heavy pAyload Unloader and Lander): The design of a reusable lunar lander with an independent cargo unloader

    NASA Technical Reports Server (NTRS)

    1991-01-01

    Project UM-Haul is the preliminary design of a reusable lunar transportation vehicle that travels between a lunar parking orbit and the lunar surface. This vehicle is an indispensible link in the overall task of establishing a lunar base as defined by the NASA Space Exploration Initiative. The response to this need consists of two independent vehicles: a lander and an unloader. The system can navigate and unload itself with a minimum amount of human intervention. The design addresses structural analysis, propulsion, power, controls, communications, payload handling and orbital operations. The Lander has the capacity to decend from low lunar orbit (LLO) to the lunar surface carrying a 7000 kg payload, plus the unloader, plus propellant for ascent to LLO. The Lander employs the Unloader by way of a motorized ramp. The Unloader is a terrain vehicle capable of carrying cargoes of 8,500 kg mass and employs a lift system to lower payloads to the ground. The system can perform ten missions before requiring major servicing.

  17. Corrosion study on high power feeding of telecomunication copper cable in 5 wt.% CaSO4.2H2O solution

    NASA Astrophysics Data System (ADS)

    Shamsudin, Shaiful Rizam; Hashim, Nabihah; Ibrahim, Mohd Saiful Bahri; Rahman, Muhammad Sayuzi Abdul; Idrus, Muhammad Amin; Hassan, Mohd Rezadzudin; Abdullah, Wan Razli Wan

    2016-07-01

    The studies were carried out to find out the best powering scheme over the copper telephone line. It was expected that the application of the higher power feeding could increase the data transfer and capable of providing the customer's satisfaction. To realize the application of higher remote power feeding, the potential of corrosion problem on Cu cables was studied. The natural corrosion behaviour of copper cable in the 0.5% CaSO4.2H2O solution was studied in term of open circuit potential for 30 days. The corrosion behaviour of higher power feeding was studied by the immersion and the planned interval test to determine the corrosion rate as well as the effect of voltage magnitudes and the current scheme i.e. positive direct (DC+) and alternating current (AC) at about 0.40 ± 0.01 mA/ cm2 current density. In the immersion test, both DC+ and AC scheme showed the increasing of feeding voltage magnitude has increased the corrosion rate of Cu samples starting from 60 to 100 volts. It was then reduced at about 100 - 120 volts which may due to the passive and transpassive mechanism. The corrosion rate was slowly reduced further from 120 to 200 volts. Visually, the positively charged of Cu cable was seems susceptible to severe corrosion, while AC scheme exhibited a slight corrosion reaction on the surface. However, the planned interval test and XRD results showed the corrosion activity of the copper cable in the studied solution was a relatively slow process and considered not to be corroded as a partially protective scale of copper oxide formed on the surface.

  18. Ho-Nee-Um Trail.

    ERIC Educational Resources Information Center

    Irwin, Harriet; And Others

    Appreciation and concern for the preservation of our natural resources by all citizens is the primary concern of this teacher's guide for use in the elementary grades. It employes the use of a filmstrip in conjunction with a local nature trail, to guide students in developing awareness - by looking closely, listening, touching, and smelling. Major…

  19. VizieR Online Data Catalog: Very Low-Luminosity Objects (VeLLOs) from 1.25-850um (Kim+, 2016)

    NASA Astrophysics Data System (ADS)

    Kim, M.-R.; Lee, C. W.; Dunham, M. M.; Evans, N. J., II; Kim, G.; Allen, L. E.

    2016-10-01

    The Spitzer Gould Belt Survey (GBS) is a project to survey about 21 square degrees of 11 nearby molecular clouds at 3.6-160um to provide a census of star formation in nearby large clouds (P.I. L. Allen). Spitzer has mapped a total of 11 molecular clouds, CMC, Chamaeleon I, Chamaeleon III, Musca, Lupus V, Lupus VI, Ophiuchus North, Aquila, CrA, Cepheus, and IC 5146 with the IRAC and MIPS between 2004 March and 2008 October. We utilized the data provided by the c2d/GBS projects (Evans et al. 2009, J/ApJS/181/321; Dunham et al. 2015, J/ApJS/220/11). There are two cloud complexes which were not listed in the c2d/GBS projects, but observed by other projects, the Taurus molecular clouds and the Orion molecular clouds. The Taurus molecular clouds have been observed over an area of ~44 square degrees by one of the GTO programs (P.I. D. Padgett) with the IRAC and the MIPS instruments. The Orion molecular clouds have been surveyed in ~9°2 area by Spitzer (P.I. T. Megeath). See section 2.1 for further details. Complementary archive infrared data were retrieved from 2MASS and Herschel PACS and SPIRE and JCMT SCUBA-2; see section 2.2. We observed our sources with the N2H+(1-0) line with the Korean Very Long Baseline Interferometry Network (KVN) 21m radio telescopes from 2011 October to 2016 May for the northern hemisphere sources, and the Mopra 22m telescope in 2012 April for the southern hemisphere sources. See section 2.3 for further explanations. (8 data files).

  20. Espectroscopia multi-objeto e imageamento de Abell 586 com GMOS - o estado dinâmico de um aglomerado de galáxias com arcos gravitacionais

    NASA Astrophysics Data System (ADS)

    Cypriano, E. S.; Sodrã©, L., Jr.; Kneib, J.-P.; Campusano, L.

    2003-08-01

    Nesse trabalho é apresentado um estudo do conteúdo de massa do aglomerado de galáxias A586 (z = 0.171) bem como sua distribuição espacial. Isso foi feito a partir de dados de espectroscopia multi-objeto e imageamento obtidos com o instrumento GMOS acoplado ao telescópio Gemini-Norte. A massa desse aglomerado foi estudada a partir da posição dos seus arcos gravitacionais (lentes fortes), da medida estatística da distorção na forma das galáxias de fundo (lentes fracas) e através da dispersão de velocidades de uma amostra de cerca de 30 galáxias pertencentes ao aglomerado (teorema do virial). Os dois primeiros métodos não dependem do estado dinâmico do aglomerado, enquanto que o terceiro sim. Desse modo, comparando seus resultados pode-se estimar o grau de relaxamento desse sistema. Dados de raios X presentes na literatura também serão incluídos nessa análise. Nossos resultados preliminares a partir das técnicas de lentes fracas, mostram que, supondo que a distribuição de massa desse aglomerado seja a de uma esfera isotérmica, espera-se que ele apresente uma dispersão de velocidades de 1330+/-78 km s-1, em contradicao com medidas similares feitas por Dahle et al. 2002 que encontram valores tão altos quanto 1680 km s-1. Já o estudo dinâmico resultou numa dispersão de velocidades de ~950 km s-1.

  1. Investigation of the hydration process in 3CaO.Al(2)O(3)-CaSO(4) . 2H(2)O-plasticizer-H(2)O systems by X-ray diffraction.

    PubMed

    Carazeanu, Ionela; Chirila, Elisabeta; Georgescu, Maria

    2002-06-10

    The development of the hydration process in 3CaO.Al(2)O(3)-CaSO(4) . 2H(2)O-H(2)O system is studied by X-ray diffraction in the presence of varying contents of new plasticizer admixtures belonging to the lignosulphonates class (calcium lignosuphonate-LSC) and condensates melamine formaldehyde sulfonated class-MSF (VIMC-11). The plasticizer admixtures were added in proportion of 0.1-1% solid substance. The influence of the plasticizer admixtures on the hydration process with increasing time is observed and it is shown to depend on the nature and content of the admixtures and the reaction time. The strong adsorption of admixtures on the surfaces on the anhydrous or partially hydrated particles of the system can explain the influence of the admixtures upon the kinetics of the hydration process retardation or acceleration. These plasticizer admixtures influence also the evolution of the hydrated compounds and forming of the hardening structure in the 3CaO.Al(2)O(3)-CaSO(4) . 2H(2)O-H(2)O system; their proportion in the system and the considered length of hardening are correlated. In the 3CaO.Al(2)O(3)-CaSO(4) . 2H(2)O-H(2)O system there are two different influences of the plasticizer admixtures upon the hydration process. One is a delaying action, as a result of plasticizer adsorption on the surface of the anhydrous and hydrated compound particles and another one is the intensifying action due to the stronger dispersion of the particles in aqueous medium.

  2. Arsenic speciation in synthetic gypsum (CaSO4·2H2O): A synchrotron XAS, single-crystal EPR, and pulsed ENDOR study

    NASA Astrophysics Data System (ADS)

    Lin, Jinru; Chen, Ning; Nilges, Mark J.; Pan, Yuanming

    2013-04-01

    Gypsum (CaSO4·2H2O) is a major by-product of mining and milling processes of borate, phosphate and uranium deposits worldwide and, therefore, potentially plays an important role in the stability and bioavailability of heavy metalloids, including As, in tailings and surrounding areas. Gypsum containing 1900 and 185 ppm As, synthesized with Na2HAsO4·7H2O and NaAsO2 in the starting materials, respectively, have been investigated by synchrotron X-ray absorption spectroscopy (XAS), single-crystal electron paramagnetic resonance spectroscopy (EPR), and pulsed electron nuclear double resonance spectroscopy (ENDOR). Quantitative analyses of As K edge XANES and EXAFS spectra show that arsenic occurs in both +3 and +5 oxidation states and the As3+/As5+ value varies from 0.35 to 0.79. Single-crystal EPR spectra of gamma-ray-irradiated gypsum reveal two types of arsenic-associated oxyradicals: [AsO3]2- and an [AsO2]2-. The [AsO3]2- center is characterized by principal 75As hyperfine coupling constants of A1 = 1952.0(2) MHz, A2 = 1492.6(2) MHz and A3 = 1488.7(2) MHz, with the unique A axis along the S-O1 bond direction, and contains complex 1H superhyperfine structures that have been determined by pulsed ENDOR. These results suggest that the [AsO3]2- center formed from electron trapping on the central As5+ ion of a substitutional (AsO4)3- group after removal of an O1 atom. The [AsO2]2- center is characterized by its unique A(75As) axis approximately perpendicular to the O1-S-O2 plane and the A2 axis along the S-O2 bond direction, consistent with electron trapping on the central As3+ ion of a substitutional (AsO3)3- group after removal of an O2 atom. These results confirm lattice-bound As5+ and As3+ in gypsum and point to potential application of this mineral for immobilization and removal of arsenic pollution.

  3. Asociación de la adherencia a la dieta mediterránea al inicio del embarazo y riesgo de gastrosquisis en la descendencia: un estudio de casos-controles

    PubMed Central

    Cánovas-Conesa, A.; Gomariz-Peñalver, V.; Sánchez-Sauco, M.F.; Vega, D.C. Jaimes; Ortega-García, J.A.; García, M.J. Aranda; Marín, J.L. Delgado; Ascanio, A. Trujillo; Hernández, F. López; Jimenez, J.I. Ruiz; de Paco Matallana, C.; Soldin, O.P.; Solís, M. Sánchez

    2016-01-01

    Resumen Objetivos El objetivo de este estudio fue estudiar la asociación de la adherencia a la dieta mediterránea materna al inicio del embarazo y el riesgo de gastrosquisis en la descendencia. Métodos Estudio de casos-control. 11 casos incidentes de gastrosquisis en la Región de Murcia de 2007 a 2012 y 34 controles concurrentes. Cuestionario validado de Frecuencia Alimentaria (CFA) sobre la dieta periconcepcional de 98 ítems realizado ‘cara a cara’ en el momento del diagnóstico. Factores confundidores: tabaquismo, expositión a cannabis/marihuana, edad materna y paterna, índice de masa corporal, ingresos económicos y nivel de estudios. Estudio descriptivo y regresión logística multivariable. Resultados Las madres de niños con gastrosquisis son más jóvenes (20,8 años; IC 95% 17,3–24,2) y su dieta tiene un menor aporte calórico, de grasas saturadas y monoinsaturadas y de proteínas que los controles. Odds Ratio (OR) en el modelo multivariable controlado por los factores confundidores: edad materna (años) 0,70 (IC95% 0,51–0,96); ácidos grasos monoinsaturados (oleico, g) 0,79 (IC95% 0,65–0,97) y consumo de vegetales (raciones/semana) 0,70 (IC95% 0,48–1,00). Conclusiones Una dieta materna rica en ácido oleico y productos vegetales podría contribuir a prevenir el riesgo de oclusión vascular de las arterias onfalomesentéricas, disminuyendo el riesgo de gastrosquisis. PMID:23833926

  4. [The effect of zeolite (clinoptilolite) on the post-feeding dynamics of N metabolism in the portal vein, jugular vein and the rumen fluid of bulls].

    PubMed

    Jacobi, U; Vrzgula, L; Blazovský, J; Havassy, I; Ledecký, V; Bartko, P

    1984-04-01

    If easily digestible saccharides are deficient in the feed ration of bulls with the live weight of 300 kg and at simultaneous single application of urea at a rate of 0.2 g per 1 kg live weight, zeolite (with 50.6% clinoptilolite content) administered at a rate of 2.5% per 1 kg dry matter influenced significantly (P less than 0.05) the ammonia concentration in rumen, v. portae and v. jugularis. The rumen contents and blood were sampled at the intervals of 0, 15, 30, 60, 90, 120, 180 and 360 minutes after feeding. Basal feed ration consisted of 1 kg feed mixture and 3 kg meadow hay. After urea administration, zeolite reduced the ammonia concentration in rumen by 20-40% in comparison with the control group and in v. portae by 60-70%. In v. jugularis in the 90th minute after feeding significant hyperammonemia was observed in bulls with no zeolite supplement. Zeolite administration did not influence urea concentration in plasma.

  5. Necrotizing Fasciitis on the Right Side of the Neck with Internal Jugular Vein Thrombophlebitis and Septic Emboli: A Case of Lemierre’s-Like Syndrome

    PubMed Central

    NGUYEN, Dang; YAACOB, Yazmin; HAMID, Hamzaini; MUDA, Sobri

    2013-01-01

    Lemierre’s syndrome (LS) is a rare life-threatening infective condition typically starting with an oropharyngeal infection causing thrombophlebitis and metastatic abscesses. The most common aetiology of LS is Fusobacterium necrophorum; however, it can also occur after infection with other organisms. LS mainly affects young healthy adults. The initial infection site can be in the head and neck or in the abdomen. The morbidity rate of this disease is high despite aggressive treatments. In this article, we report a 63-year-old male patient with uncontrolled diabetes mellitus, presenting with Klebsiella pneumoniae infection-induced necrotizing fasciitis on the right side of the neck, leading to LS. PMID:24643401

  6. Análise sobre o Conhecimento de um Grupo de Alunos do Ensino Médio da Rede Estadual de São Paulo sobre Termos e Fenômenos Astronômicos do Cotidiano

    NASA Astrophysics Data System (ADS)

    de Oliveira, E. F.; Voelzke, M. R.; Amaral, L. H.

    2007-08-01

    Embora os Parâmetros Curriculares Nacionais do Ensino Médio (PCN-EM) e as orientações complementares a esses Parâmetros (PCN+) apontem a importância de uma abordagem significativa de conceitos relacionados à astronomia nas aulas de Física, muitos estudantes terminam o Ensino Médio (EM) sem compreender a razão de certos acontecimentos de origem celeste, ainda que estes façam parte de seu cotidiano. Este trabalho tem por objetivo analisar os conhecimentos básicos em astronomia dos alunos de EM da escola estadual Batista Renzi, bem como investigar os meios através dos quais estes conhecimentos foram adquiridos. Para tanto foi elaborado um questionário de múltipla escolha aplicado a 310 alunos distribuídos entre as três séries do EM dos períodos matutino e noturno. Dessa forma, observou-se que apenas 34,5% relacionaram as estações do ano à inclinação do eixo de rotação da Terra, 21,3% indicaram a influência gravitacional da Lua e do Sol como responsáveis pelo fenômeno das marés, 24,5% indicaram corretamente quais são os objetos celestes mais próximos da Terra, 36,1% identificaram ano-luz como uma medida de distância e 34,2% reconheceram uma estrela cadente como meteoro. Em contrapartida, 67,1% compreendiam a sucessão entre dia e noite, 73,9% identificaram o Sol como estrela e 52,3% relacionaram o Big Bang à origem do Universo. Além disso, foram comparadas as respostas de alunos de diferentes séries e períodos, observando-se, dentre outras coisas, que os estudantes do terceiro ano apresentam um percentual de acertos semelhante ao dos alunos do primeiro, caracterizando que a abordagem de tópicos relacionados à astronomia no EM não tem contribuído para uma maior compreensão dos fenômenos e conceitos.

  7. Percepção astronómica de um grupo de alunos do ensino médio de uma escola da rede estadual de São Paulo

    NASA Astrophysics Data System (ADS)

    de Oliveria, E. F.; Voelzke, M. R.

    2009-03-01

    Sendo a Astronomia uma das cièncias mais antigas da humanidade, e considerando sua importáncia histórica e cultural, é de extrema releváncia que tópicos relacionados a ela sejam tratados nas escolas. Embora os Parámetros Curriculares Nacionais do Ensino Médio (PCN-EM) e as Orientaçiacute;es Complementares aos Parámetros (PCN+) apontem a importáncia de uma abordagem significativa de conceitos relacionados à Astronomia nas aulas de Física, muitos estudantes terminam o Ensino Médio (EM) sem compreender a razão de certos acontecimentos de origem celeste, ainda que estes façam parte de seu cotidiano e sejam alvos da curiosidade natural dos jovens. Da observação dessa curiosidade em alunos de uma escola pública paulista, na cidade de Suzano, surgiu o interesse em investigar os conhecimentos básicos em Astronomia dos alunos do Ensino Médio desta escola, constituindo-se este como principal objetivo desta pesquisa. Para tanto foi elaborado um questionário de múltipla escolha aplicado inicialmente a 34 alunos do primeiro ano e, posteriormente, a mais 310, distribuídos entre as très séries do Ensino Médio dos períodos matutino e noturno. Dessa forma, observou-se que 73,9% dos estudantes identificaram o Sol como sendo uma estrela, 67,1% mostraram compreender a sucessão entre dia e noite e 52,3% relacionaram o Big Bang à origem do Universo. Em contrapartida, apenas 34,5% relacionaram as estaçíes do ano à inclinação do eixo de rotação da Terra, 21,3% indicaram a influència gravitacional simultánea da Lua e do Sol como responsável pelo fenòmeno das marés, 24,5% indicaram corretamente quais são os objetos celestes mais próximos da Terra, 36,1% identificaram ano-luz como uma medida de distáncia e 34,2% reconheceram as estrelas cadentes como meteoros, evidenciando-se assim o pequeno discernimento dos estudantes quanto aos fenòmenos e termos astronòmicos do cotidiano. Além disso, foram comparadas as respostas de alun! os de diferentes s

  8. Ultrawide bandwidth 1.55-um lasers

    NASA Astrophysics Data System (ADS)

    Morton, Paul A.; Tanbun-Ek, Tawee; Logan, Ralph A.; Ackerman, David A.; Shtengel, Gleb E.; Yadvish, R. D.; Sergent, A. M.; Sciortino, Paul F., Jr.

    1996-04-01

    This paper describes the essential elements for creating a practical wide bandwidth directly modulated laser source. This includes considerations of the intrinsic limitations of the laser structure, due to the resonant frequency and damping of the laser output, together with carrier transport issues to allow carriers in the device active region to be efficiently modulated at high speeds. the use of a P-doped compressively strained multiple-quantum well active region to provide high intrinsic speed and remove transport limitations is described, together with record setting results of 25 GHz modulation bandwidth for a 1.55 micrometer Fabry-Perot laser and 26 GHz bandwidth for a 1.55 micrometer DFB laser. The challenges of providing high bandwidth electrical connections to the laser on a suitable submount, together with fiber attachment and microwave packaging, are discussed. Results of fully packaged 1.55 micrometer DFB lasers with 25 Ghz modulation bandwidth are shown. Digital modulation of the packaged 1.55 micrometer DFB including impedance matching is described, and the transient wavelength chirp is presented. This low chirp is reduced further using an optical filter, to provide a 10 GBit/s source with chirp similar to that of an external electroabsorption modulator.

  9. El rol de Ia colaboracion y el Modelo de Aprendizaje Basado en Proyectos (ABPr) mediante el lente de la Teoria de Actividad (CHAT): un estudio de caso con estudiantes de 9no grado

    NASA Astrophysics Data System (ADS)

    Delgado, Isabel C.

    Los modelos de eensenanza y aprendizaje constructivistas conceptualizan el aprendizaje como un proceso activo. El modelo de Aprendizaje Basado en Proyectos (ABPr) se distingue por una serie de componentes, entre los cuales se destaca el aspecto colaborativo y cooperativo como un reto al momento de su implantacion. Son pocas las investigaciones que se concentran en este aspecto del modelo. En este estudio, se analizaron las diversas interacciones que surgen durante la implantacion de una unidad curricular sobre el tema de Geologia de Puerto Rico, la cual se diseno con el modelo ABPr cuyo enfoque es orientacion a proyectos. Particularmente, se examinaron las interacciones sociales que surgen entre los pares y entre pares y docente durante el proceso de planificacion y desarrollo de los productos finales, al igual que las interacciones entre los estudiantes y el material didactico en estas etapas del modelo. La investigacion es de tipo cualitativo e incorpora como diseno el estudio de caso. Las diversas interacciones constituyen la unidad de analisis. En el estudio participaron 19 estudiantes de 9no grado, a quienes se organizaron en 5 grupos colaborativos por temas de interes (Pangea, Placas tectonicas, Volcanes, Tsunamis y Terremotos). Las tecnicas que se utilizaron para recopilar los datos fueron: observaciones participativas, grupos focales y analisis de documentos (cuadernos reflexivos y respuestas de los estudiantes a la pregunta central del proyecto). Para el analisis de los datos se aplico la teoria de actividad (CHAT) que concentra la unidad de analisis en la actividad humana en un contexto particular. Los resultados del estudio senalan que las interacciones entre pares, entre pares y docente, asi como entre estudiantes y material didactico son fundamentales en el proceso de aprendizaje. Una mayor interaccion entre pares durante las etapas de planificar y desarrollar los productos finales de la unidad, promueve una mejor comprension de los conceptos de la

  10. Precise and accurate isotope fractionation factors (α17O, α18O and αD) for water and CaSO4·2H2O (gypsum)

    NASA Astrophysics Data System (ADS)

    Gázquez, Fernando; Evans, Nicholas P.; Hodell, David A.

    2017-02-01

    Gypsum (CaSO4·2H2O) is a hydrated mineral containing crystallization water, also known as gypsum hydration water (GHW). We determined isotope fractionation factors (α17O, α18O and αD) between GHW and free water of the mother solution in the temperature range from 3 °C to 55 °C at different salinities and precipitation rates. The hydrogen isotope fractionation factor (αDgypsum-water) increases by 0.0001 units per °C between 3 °C and 55 °C and salinities <150 g/L of NaCl. The αDgypsum-water is 0.9812 ± 0.0007 at 20 °C, which is in good agreement with previous estimates of 0.981 ± 0.001 at the same temperature. The α18Ogypsum-water slightly decreases with temperature by 0.00001 per °C, which is not significant over much of the temperature range considered for paleoclimate applications. Between 3 °C and 55 °C, α18Ogypsum-water averages 1.0035 ± 0.0002. This value is more precise than that reported previously (e.g. 1.0041 ± 0.0004 at 25 °C) and lower than the commonly accepted value of 1.004. We found that NaCl concentrations below 150 g/L do not significantly affect α18Ogypsum-water, but αDgypsum-water increases linearly with NaCl concentrations even at relatively low salinities, suggesting a salt correction is necessary for gypsum formed from brines. Unlike oxygen isotopes, the αDgypsum-water is affected by kinetic effects that increase with gypsum precipitation rate. As expected, the relationship of the fractionation factors for 17O and 18O follows the theoretical mass-dependent fractionation on Earth (θ = 0.529 ± 0.001). We provide specific examples of the importance of using the revised fractionation factors when calculating the isotopic composition of the fluids.

  11. Determinação da massa de júpiter a partir das órbitas de seus satélites: um experimento didático

    NASA Astrophysics Data System (ADS)

    Schlickmann, M. S.; Saito, R. K.; Becker, D. A.; Rezende, M. F., Jr.; Cid Fernandes, R.

    2003-08-01

    Este trabalho apresenta o roteiro piloto de uma prática observacional em astronomia, junto com os primeiros resultados obtidos nesta fase de implementacão. O projeto, que será executado em duas etapas, visa introduzir noções de Astronomia a alunos do Ensino Médio e iniciantes nos cursos de Física. O experimento consiste em medir as órbitas dos satélites Galileanos e, a partir da análise dos dados coletados, verificar a validade da Lei das órbitas de Kepler, determinando a massa do planeta Júpiter. Em uma primeira etapa, as observações serão feitas utilizando um telescópio Meade LX200 10" e câmera CCD para obter uma seqüência de imagens do planeta, que possibilitará medir o movimento de seus satélites. A segunda etapa terá início a partir do funcionamento do telescópio em modo robótico, com a possibilidade de observações via internet por instituições de ensino. Para o desenvolvimento deste experimento foram inicialmente coletadas várias imagens de Júpiter obtidas com os instrumentos citados acima. Estas imagens serviram como base para confecção dos roteiros para a experiência no nível médio e superior. Os roteiros serão inicialmente apresentados em uma home-page. Nela também se buscará uma contextualização histórica da experiência bem como o estabelecimento de relações com professores e alunos, propostas metodológicas e a disponibilização dos programas computacionais necessários para a utilização "on-line" pelos usuários. O projeto conta com apoio da Fundação VITAE.

  12. Double-lumen catheter in the right jugular vein induces two sub-endothelial abscesses in an unusual place, the transition between the superior vena cava and the right atrium: a case report

    PubMed Central

    2014-01-01

    Endocarditis is a type of infection that is common in internal medicine wards and in haemodialysis clinics. The location that is most affected are the heart valves. Herein, we report a case of an uncommon abscess, a sub-endothelial abscess between the transition of the superior vena cava and the right atrium. There were several emboli to the lung and foot, and the agent was related to Staphylococcus aureus and a double-lumen catheter. Usually, this type of abscess is located in valves, either the tricuspid valve if related to catheters or injection drug use or the mitral valve if related to other causes. An exhaustive review was made, but we found no information about the location of this abscess and the rarity of the event motivating the report of infection. PMID:25110520

  13. Comparative research on medicine application with 0.53-um, 1.06-um, and 1.32-um Nd:YAG lasers

    NASA Astrophysics Data System (ADS)

    Li, Yahua; Li, Zhenjia; Zhu, Changhong; Huang, Yizhong

    1996-09-01

    Because of its high power and excellent optical features, laser has almost been applied to everywhere of medical research and clinic. Over the past several years, laser medical has achieved a rapid progress, and laser medical instruments has developed promptly, each new wavelength can be successfully applied in diagnostic and treatment of diseases. Among the medical lasers, Nd:YAG solid-state laser systems have proven useful in surgical use operate, such as neurosurgery, gastroenterology, cardioangiology, urology, gynecology, dermatology and ENT. As with other solid-state lasers, the Nd:YAG laser can be made to emit various wavelengths by means of suitable resonator configurations and some newest solid-state laser technology, pumped by the Krypton lamp, the Nd:YAG laser at room temperature exhibits transition at 1.06 micrometer Nd:YAG, using nonlinear crystal and Q-switch to double its frequency can attain 0.53 micrometer green beam. In our laser systems, the efficiency at 1.06 micrometer is more than 3 percent, an efficiency of 0.5 percent at 1.32 micrometer and 0.53 micrometer can be attained. For a power of 100w at 1.06 micrometer, 15w at 1.32 micrometer and 0.53 micrometer can therefore be produced. All of three kinds Nd:YAG laser hold these characteristics: high output power; optical fiber transition that can be cooperated with endoscope. The paper mainly discusses laser operating characteristics and clinic applications of three kinds wavelengths at 0.53 micrometer 1.06 micrometer and 1.32 micrometer Nd:YAG laser systems.

  14. The Shadow of a Gnomon Along a Year: Routine Observations and Teaching of Apparent Motion of the Sun and the Four Seasons. (Spanish Title: La Sombra de un Gnomon lo Largo de un Año: Observaciones de Rutina y la Enseñanza del Movimiento Aparente del Sol y Las Cuatro Estaciones.) A Sombra de um Gnômon ao Longo de um Ano: Observações Rotineiras e o Ensino do Movimento Aparente do Sol E das Quatro Estações

    NASA Astrophysics Data System (ADS)

    Trogello, Anderson Giovani; Danhoni Neves, Marcos Cesar; de Carvalho Rutz da Silva, Sani

    2013-12-01

    , al solsticio de junio, al equinoccio de septiembre y al solsticio de diciembre. Además, se dictaron clases teóricas en la sala de aula. Estos métodos buscaron construir conceptos en torno al movimiento aparente del Sol y la sucesión de las estaciones. Teniendo en cuenta los resultados de las actividades se aplicó una evaluación cuyos datos demuestran la existencia de un aprendizaje deseado por los estudiantes en cuanto a: el reconocimiento de los puntos cardinales, la descripción del movimiento solar aparente y la aparición de las estaciones y su alternancia a partir de observaciones astronómicas visuales sin instrumentos. Muitas concepções alternativas são reconhecidas entre os diversos grupos de estudantes, em especial nos da educação básica. Dentre elas, o movimento aparente do Sol, por mais quotidiano que seja, proporciona variadas interpretações. Deste modo, observar e registrar o movimento dos astros na abóboda celeste é uma tarefa necessária ao ensino de Astronomia. O trabalho que ora se apresenta propõe a apresentação dos resultados da observação do movimento aparente do Sol por intermédio da marcação da sombra de um gnômon vertical por alunos de uma turma do sexto ano do ensino fundamental de uma escola do campo do Paraná. O projeto em si ocorreu em quatro etapas, em datas próximas do equinócio de março, do solstício de junho, do equinócio de setembro e do solstício de dezembro. Além disso, foram desenvolvidas aulas teóricas em sala de aula. Tais métodos buscaram construir conceitos em torno da movimentação aparente do Sol e da alternância das estações do ano. Diante dos resultados provenientes das atividades desenvolvidas foi aplicada uma avaliação e os dados demonstraram um aprendizado desejado dos alunos quanto: ao reconhecimento dos pontos cardeais; à descrição do movimento solar aparente e a ocorrência das estações do ano e sua alternância a partir de observações astronômicas a olho nu.

  15. [The anatomical variations of the extensor muscles of the hand fingers].

    PubMed

    Melo, Catarina; Coelho, Paulo; Bernardes, António

    2013-01-01

    Introdução: Os músculos extensores dos dedos da mão estão sujeitos a múltiplas variações, algumas bastante frequentes.Material e Métodos: Foi efectuada a dissecção da região posterior do antebraço e mão de dois cadáveres, documentando-se as variações anatómicas encontradas.Resultados: No Caso 1 o extensor comum dos dedos emitia cinco tendões: um para o 2º dedo, um para o 3º dedo, dois para o 4º dedo e um para o 5º dedo; o extensor próprio do indicador emitia dois tendões: um para o dedo indicador e um para o 3º dedo. No Caso 2 o extensor comum dos dedos emitia quatro tendões: um tendão que se unia ao tendão do longo extensor do polegar, um para o 2º dedo, um para o 3º dedo e um para o 4º dedo que, por sua vez, emitia um tendão que se unia ao tendão do extensor do dedo mínimo; o extensor próprio do indicador emitia dois tendões: um para o dedo indicador e outro para o 3º dedo; o extensor do dedo mínimo emitia dois tendões para o 5º dedo.Discussão/Conclusões: A existência de um tendão duplo do extensor comum dos dedos para o 4º dedo tem sido verificada frequentemente em alguns estudos. É raro existir um tendão do extensor comum dos dedos para o longo extensor do polegar. Um tendão duplo do extensor do dedo mínimo pode ocorrer em 60 a 90% dos casos em alguns estudos. O conhecimento das variações mais frequentes dos tendões dos extensores dos dedos é importante para a prática cirúrgica.

  16. Astronomy in High School: Using a Mini-Planetarium to Understand Details of the Apparent Movement of Stars. (Spanish Title: Astronomía en la Escuela Secundaria: Comprendiendo los Detalles del Movimiento Aparente de Las Estrellas con un Miniplanetario.) Astronomia no Ensino Médio: Compreendendo Detalhes do Movimento Aparente das Estrelas com um Miniplanetário

    NASA Astrophysics Data System (ADS)

    dos Santos Leão, Demetrius

    2013-07-01

    en la comprensión de estas cuestiones y demostraron un gran interés por esta metodología. O objetivo deste artigo é apresentar parte dos resultados obtidos com a intervenção feita como projeto da dissertação de mestrado do autor, que consistiu no desenvolvimento de um conjunto de aulas de Astronomia, com alunos do 1º Ano do Ensino Médio de uma escola da rede privada do Distrito Federal (Brasília, Brasil), empregando como recurso principal um material didático chamado miniplanetário (MP). Utilizando como pressuposto teórico norteador dessas aulas as ideias de contextualização e dialogicidade de Paulo Freire, foi proposta aos estudantes a montagem e utilização desse recurso em uma sessão de planetário. Durante o projeto, enfatizaram-se assuntos como a trajetória aparente das estrelas para o céu de Brasília, a localização dos pontos cardeais a partir da constelação do Cruzeiro do Sul, as cores das estrelas e as estrelas vistas de uma determinada localidade. Apurou-se que os alunos apresentaram melhoria na compreensão desses assuntos, bem como demonstraram expressiva empolgação com essa metodologia desenvolvida.

  17. Grant UM1CA167462 | Division of Cancer Prevention

    Cancer.gov

    The Division of Cancer Prevention (DCP) conducts and supports research to determine a person's risk of cancer and to find ways to reduce the risk. This knowledge is critical to making progress against cancer because risk varies over the lifespan as genetic and epigenetic changes can transform healthy tissue into invasive cancer.

  18. High-sensitivity (25-um pitch) microbolometer FPAs

    NASA Astrophysics Data System (ADS)

    Murphy, Daniel F.; Ray, Michael; Wyles, Richard; Asbrock, James F.; Lum, Nancy A.; Kennedy, Adam; Wyles, Jessica; Hewitt, C.; Graham, Glen E.; Horikiri, Tad; Anderson, John S.; Bradley, Daryl; Chin, Richard; Kostrzewa, Thomas

    2001-11-01

    RIO has achieved a significant technical breakthrough in uncooled FPAs by reducing the pixel size by a factor of two while maintaining state-of-the-art sensitivity. Raytheon has produced high-quality 320 by 240 micro bolometer FPAs with 25 micrometers pitch pixels. The 320 by 240 FPAs have a sensitivity that is comparable to micro bolometer FPAs with 50 micrometers pixels. The average NETD value for these FPAs is about 35 mK with an f/1 aperture and operating at 30 Hz frame rates. Good pixel operability and excellent image quality have been demonstrated. Pixel operability is greater than 99 percent on some FPAs, and uncorrected responsivity nonuniformity is less than 4 percent. The micro bolometer detectors also have a relatively fast thermal time constant of approximately 10 msec. This state-of-the-art performance has been achieved as a result of an advanced micromachining fabrication process. The process allows maximization of both the thermal isolation and the optical fill-factor. The reduction in pixel size offers several potential benefits for IR systems. For a given system resolution requirement, the 225 micrometers pixels allow a factor of two reduction in both the focal length and aperture size of the sensor optics. The pixel size reduction facilitates a significant FPA cost reduction since the number of die printed on a wafer can be increased. The pixel size reduction has enabled the development of a large-format 640 by 512 FPA array applicable to wide-field-of-view, long range surveillance and targeting missions, and a 160 by 128 array where applications for miniaturization and temperature invariance are required as well as low cost and low power.

  19. Um Olhar sobre "Beleza Americana" (A Look at "American Beauty").

    ERIC Educational Resources Information Center

    Bissoto, Maria Luisa

    2000-01-01

    Discusses the film "American Beauty" in light of a reading of Karl Marx. Finds that the film shows the circularity which marks bourgeois society, even though the rhythm of industry and renovation of the society masks it. States that Marx praises the industry, invention, and innovation of the bourgeoisie. (BT)

  20. Handling a Tricky Verb: Es handelt sich um "handeln".

    ERIC Educational Resources Information Center

    Kuhn-Osius, K. E.

    1987-01-01

    Attempts to establish a practical approach to teaching the various meanings of the German verb "handeln". Exercises that aid advanced students in understanding the verb's meaning include a complete list of all possible meanings of the verb, as well as sample sentences using the verb in a wide range of contexts. (LMO)

  1. Spatial deconvolution of IRAS galaxies at 60 UM

    NASA Technical Reports Server (NTRS)

    Low, Frank J.

    1987-01-01

    Using IRAS in a slow scan observing mode to increase the spatial sampling rate and a deconvolution analysis to increase the spatial resolution, several bright galaxies were resolved at 60 micron. Preliminary results for M 82, NGC 1068, NGC 3079 and NGC 2623 show partially resolved emission from 10 to 26 arcsec., full width at half maximum, and extended emission from 30 to 90 arcsec. from the center. In addition, the interacting system, Arp 82, along with Mark 231 and Arp 220 were studied using the program ADDSCAN to average all available survey mode observations. The Arp 82 system is well resolved after deconvolution and its brighter component is extended; the two most luminous objects are not resolved with an upper limit of 15 arcsec. for Arp 220.

  2. IUE ultraviolet observations of W UM a Stars

    NASA Technical Reports Server (NTRS)

    Dupree, A. K.; Preston, S.

    1981-01-01

    International Ultraviolet Explorer observations of four W UMa eclipsing binary systems (44 Boo, VW Cep, W UMa, and epsilon) are discussed. The stars generally show large surface fluxes of high temperature lines (C II, C IV, N V, Si IV) which may result from the high rotational velocities forced by synchronous rotation. High dispersion spectra of the 44 Boo system in the Mg II line enable the individual stellar components to be identified. The line widths and phase variations are consistent with the optically determined spectroscopic orbit. Circumstellar absorption of Mg II may be presented at selected phases.

  3. Thermal levitation of 10 um size particles in low vacuum

    NASA Astrophysics Data System (ADS)

    Fung, Long Fung Frankie; Kowalski, Nicholas; Parker, Colin; Chin, Cheng

    2016-05-01

    We report on experimental methods for trapping 10 micron-sized ice, glass, ceramic and polyethylene particles with thermophoresis in medium vacuum, at pressures between 5 Torr and 25 Torr. Under appropriate conditions particles can launch and levitate robustly for up to an hour. We describe the experimental setup used to produce the temperature gradient necessary for the levitation, as well as our procedure for generating and introducing ice into the experimental setup. In addition to analyzing the conditions necessary for levitation, and the dependence of levitation on the experimental parameters, we report on the behavior of particles during levitation and ejection, including position and stability, under different pressures and temperatures. We also note a significant discrepancy between theory and data, suggesting the presence of other levitating forces.

  4. Astronomy around 1700. (German Title: Astronomie um 1700)

    NASA Astrophysics Data System (ADS)

    Herbst, Klaus-Dieter

    The book focuses on Gottfried Kirch und Olaus Römer, two scholars who played a leading role in astronomy around 1700. It contains an annotated edition of the letter by Gottfried Kirch to Olaus Römer of October 25, 1703. Kirch was the astronomer of the Berlin Academy of Sciences since 1700, recognized both as astronomical calculator and as observer - Römer was director of the Copenhagen Observatory and was the first who determined the speed of light. Kirch's letter to Römer of October 1703, given here together with several addenda, was not a letter in the modern sense, but a treatise of broad contents, dealing with different astronomical items of that time: the problem of determining stellar and planetary positions, the subjective view on contemporaries, the methods of astronomical calculations, the discovery of comets and other questions are described in Kirch's vivid words. Numerous annotations by the editor explain the astronomy of that time. The editor leads the reader step by step through the methods of astronomical calculations, which become clear and understandable. A complete bibliography of works by and about Kirch and a list of known archival sources are added.

  5. Grant UM1CA182883 | Division of Cancer Prevention

    Cancer.gov

    The Division of Cancer Prevention (DCP) conducts and supports research to determine a person's risk of cancer and to find ways to reduce the risk. This knowledge is critical to making progress against cancer because risk varies over the lifespan as genetic and epigenetic changes can transform healthy tissue into invasive cancer.

  6. Discussions about the Nature of Science in a Course on the History of Astronomy. (Spanish Title: Discusiones sobre la Naturaleza de la Ciencia en un Curso sobre Historia de la Astronomía.) Discussões sobre a Natureza da Ciência em um Curso sobre a História da Astronomia

    NASA Astrophysics Data System (ADS)

    Pires de Andrade, Victória Flório; L'Astorina, Bruno

    2010-07-01

    There are an increasing number of researches in science education that affirm the importance of discussions on the "nature of science" in basic education level as well as in teacher training. The history of science applied to education is a way to contextualize epistemological discussions, allowing both the understanding of scientific content and learning about science concepts. We present some reasonably consensual definitions on the nature of science that have been widely discussed by the academic community. We show also some episodes in the history of astronomy which can lead to discussions involving some aspects of the nature of science, and how they can do it. Hay un número creciente de investigaciones en la enseñanza de las ciencias que afirman la importancia de debates sobre la "naturaleza de la ciencia" en la educación básica y formación del profesorado. La historia de la ciencia aplicada a la educación es una manera de contextualizar los debates de la epistemología, lo que permite tanto la comprensión de los contenidos científicos como el aprendizaje de conceptos científicos. En esto trabajo, presentamos algunas definiciones bastante consensuales sobre la naturaleza de la ciencia que han sido ampliamente discutidas por la comunidad académica y mostramos cómo algunos episodios en la historia de la astronomía pueden llevar a discusiones sobre algunos aspectos de la naturaleza de la ciencia. Há um número crescente de pesquisas na área de ensino de ciências que afirmam a importância de discussões sobre a "natureza da ciência" na educação básica e na formação de professores. A história da ciência aplicada ao ensino é uma maneira de contextualizar discussões epistemológicas, permitindo tanto a compreensão de conteúdos científicos quanto o aprendizado de noções sobre as ciências. Neste trabalho apresentamos algumas definições razoavelmente consensuais sobre a natureza da ciência que foram amplamente discutidas pela

  7. [Thyroid Metastasis as the Initial Presentation of an Asymptomatic Clear Cell Renal Carcinoma].

    PubMed

    Carmelino, Janine; Tavares, Ana Paula; Crespo, Ana; Coutinho, José Mário; Lázaro, António; Ribeiro, Vasco; Barroso, Eduardo

    2016-11-01

    Introdução: A metastização para a glândula tiroideia de um carcinoma renal de células claras é rara e só diagnosticável após análise imunohistoquímica de uma amostra histológica. O objetivo deste artigo é reportar um caso de metastização tiroideia como primeira manifestação de um carcinoma renal de células claras.Caso Clínico: Doente do sexo masculino com um nódulo sólido no lobo esquerdo da tiróide, com 5,3 cm, suspeito de malignidade, submetido a tiroidectomia total com linfadenectomia do compartimento central. A análise histológica concluiu serem duas metástases de carcinoma renal de células claras. Após estudo dirigido ao rim, o doente foi submetido a nefrectomia radical quatro meses depois. Discussão: O interesse deste caso reside no facto de a metastização para a tiroide como primeira manifestação de carcinoma renal de células claras ser rara mas, se tratada precocemente, permite uma ‘dupla resseção cirúrgica’ que pode levar a sobrevidas aos cinco anos de 80%.

  8. Astronomy Teaching and Teachers Continuing Education: the Interdisciplinarity during a Total Lunar Eclipse. (Spanish Title: Enseñanza de la Astronomía y la Formación Continua de Profesores: la Interdisciplinariedad Durante un Eclipse Total de Luna.) Educação EM Astronomia E Formação Continuada de Professores: a Interdisciplinaridade Durante um Eclipse Lunar TOTAL

    NASA Astrophysics Data System (ADS)

    Langhi, Rodolfo

    2009-07-01

    This paper describes how 67 teachers from 23 cities, could awaken, in students, the scientific interest, using a natural astronomical phenomenon: a total lunar eclipse. Before and after of eclipse, meetings for continuing education were characterized by interdisciplinarity of astronomy and the importance of these observations. Working groups were formed by teachers and students, who organized the survey data, mobilizing the people in their cities. The results point ways about how to provide the scientific culture and the motivation to learn science in students, using approaches between the following communities: scientific, amateur and school. En este artículo se describe cómo 67 profesores de 23 ciudades, despertó el interés científico en los estudiantes mediante un fenómeno astronómico: un eclipse total de Luna. Antes y después del eclipse, reuniones para la formación continua se centraron en la interdisciplinariedad de la astronomía, y la importancia de las observaciones de este tipo de fenómeno. Profesores y estudiantes formaron grupos de trabajo para investigar datos durante el eclipse, con el participación de la comunidad en sus ciudades. Los resultados apuntan a las opciones que conducen a la cultura científica y la motivación para aprender la ciencia, utilizando las relaciones de los siguientes grupos: científicos, aficionados y la escuela. Este texto relata como 67 professores, provenientes de 23 cidades, puderam despertar, nos alunos, o interesse científico utilizando um fenômeno natural astronômico: um eclipse lunar total. O evento foi precedido e procedido por encontros de formação continuada, onde se caracterizou a interdisciplinaridade da astronomia e a importância das observações de fenômenos como estes. Grupos de trabalho foram formados por professores e alunos, que se organizaram para o levantamento conjunto de dados durante o fenômeno, além do envolvimento da comunidade em suas respectivas cidades. Os resultados apontam

  9. Right hepatic artery aneurysm.

    PubMed

    Bernal, Astrid Del Pilar Ardila; Loures, Paulo; Calle, Juan Cristóbal Ospina; Cunha, Beatriz; Córdoba, Juan Camilo

    2016-01-01

    We report a case of an aneurysm of the right hepatic artery and its multidisciplinary management by general surgery, endoscopy and radiology services. Being a case of extremely low incidence, it is important to show its diagnostic and therapeutic approach. RESUMO Relatamos um caso de aneurisma da artéria hepática direita conduzido de forma multidisciplinar pelos Serviços de Cirurgia Geral, Endoscopia e Radiologia. Em se tratando de caso de incidência baixíssima, é importante mostrar o enfoque diagnóstico e terapêutico usado em seu manejo.

  10. The Understanding of Astronomy Concepts by Students from Basic Education of a Public School. (Spanish Title: El Entendimiento de Conceptos de Aastronmía Por Los Alumnos de Educación Básica en Una Escuela Pública.) O Entendimento de Conceitos de Astronomia Por Alunos da Educação Básica: O Caso de Uma Escola Pública Brasileira

    NASA Astrophysics Data System (ADS)

    Iria Machado, Daniel; dos Santos, Carlos

    2011-07-01

    movimiento de la Luna, el movimiento aparente del Sol sobre la esfera celeste, los eclipses, las dimensiones y las distancias en el Universo, el brillo de las estrellas y su observación de la Tierra. Si bien ha habido un pequeño progreso en la proporción de respuestas aceptables científicamente cuando se cotejó el octavo grado de la enseñanza primaria con el quinto, y el último año de la enseñanza secundaria con el primero, se observó un predominio de las concepciones alternativas en relación a la mayoría de los temas explorados, que continuó hasta los últimos años de la educación básica. Una comparación con los datos encontrados en investigaciones realizadas en otros contextos socioculturales revelaron, en muchos aspectos, conceptos y dificultades similares expresadas por los estudiantes. Apresentam-se os resultados de uma investigação sobre a compreensão de conceitos astronômicos básicos, da qual participaram 561 estudantes da quinta série do Ensino Fundamental ao terceiro ano do Ensino Médio de uma escola pública da cidade de Foz do Iguaçu. Um teste com 20 questões de múltipla escolha foi aplicado para identificar as concepções mais comuns expressadas pelos alunos. Esse instrumento de coleta de dados foi elaborado com base na literatura sobre concepções alternativas e abordou os seguintes temas: o ciclo dia-noite; os fusos horários; as estações do ano; as fases da Lua; o movimento da Lua; o movimento aparente do Sol na esfera celeste; os eclipses; as dimensões e distâncias no Universo; o brilho das estrelas e sua observação da Terra. Embora se tenha verificado um pequeno progresso na proporção de respostas cientificamente aceitáveis ao se cotejar a oitava série do Ensino Fundamental com a quinta, e a terceira série do Ensino Médio com a primeira, houve o predomínio de concepções alternativas em relação à maior parte dos temas explorados, as quais persistiram até o último ano da Educação Básica. A comparação com

  11. The Practice of Research of a Basic Education Teacher Involving Mental Models of the Phases of the Moon and Eclipses. (Spanish Title: La Práctica de Investigación de un Maestro de Educación BÁsica con El Uso de los Modelos Mentales de Las Fases de la Luna Y Eclipses.) A Prática de Pesquisa de um Professor do Ensino Fundamental Envolvendo Modelos Mentais de Fases da Lua e Eclipses

    NASA Astrophysics Data System (ADS)

    Pessôa Queiroz, Glória; Jubitipan Borges de Sousa, Carlos; Auxiliadora Delgado Machado, Maria

    2009-12-01

    docente. La formación de grupos interinstitucionales para la planificación de la acción y la investigación ha resultado productiva para el trabajo de construcción de conocimiento de apoyo a los procesos educativos en la escuela, mientras que la universidad enriquece su colección de experiencias validadas, considerando los resultados de la educación inicial y continua de maestros. La participación activa del maestro en un grupo de investigación en la universidad lo llevó a reflexiones sobre los posibles caminos didácticos que pueden ser descriptos, analizados y comunicados a los demás docentes. La construcción de una pedagogía propia, que tuvo en cuenta los modelos mentales de los estudiantes sobre los temas básicos de astronomía, y los cambios desarrollados a partir de las lecciones que enseñó, trajeron consecuencias de largo alcance sobre la pedagogía adoptada por el maestro, que ahora incorpora una nueva visión de la ciencia y formas alternativas al diálogo con los estudiantes, los componentes esenciales para un investigador en Educaciónen Ciencias. A inclusão do professor da escola básica no universo da pesquisa é questão controvertida e em pleno debate no meio acadêmico. A oportunidade de trabalho coletivo que incorporou professores de uma escola municipal no Rio de Janeiro a um grupo de ensino de Física da universidade nos possibilitou vislumbrar a ressignificação da função de um professor de Ciências (co-autor deste trabalho) por ele próprio, agora passando a incluir a pesquisa sobre a construção de conhecimento pelos alunos em sua prática como docente. A formação de grupos interinstitucionais para o planejamento de ações e de pesquisas tem-se mostrado produtiva para um trabalho de construção de conhecimentos a fim de subsidiar processos educativos na escola, ao mesmo tempo em que a universidade enriquece seu acervo de experiências validadas criticamente, podendo considerar seus resultados na formação inicial e

  12. Eccrine porocarcinoma: cytologic diagnosis by fine needle aspiration biopsy (FNAB).

    PubMed

    Kalogeraki, Alexandra; Tamiolakis, Dimitrios; Tsagatakis, Thomas; Geronatsiou, Katerina; Haniotis, Vrettos; Kafoussi, Maria

    2013-01-01

    Introdução: O porocarcinoma écrino (PE) é um tumor maligno pouco comum dos anexos cutâneos. Trata-se de um adenocarcinoma da glândula sudorípara écrina com propensão para recorrer localmente e para originar metástases ao longo dos gânglios linfáticos regionais. Este artigo apresenta um diagnóstico por citologia aspirativa com agulha fina (CAAF) de um PE, associado ao exame histológico e de imunocito/histoquímica.Caso Clínico: São descritos os achados da citologia de um porocarcinoma écrino numa doente de 76 anos de idade, bem como as características histológicas do tumor cutâneo. A citologia aspirativa revelou que o tumor se caracterizava pela presença de células atípicas malignas com citoplasma basófilo, núcleos hipercromáticos e nucléolos proeminentes. O diagnóstico citológico foi confirmado pela histologia.Conclusões: É crucial obter um diagnóstico pré-operatório preciso de modo a desencadear um plano cirúrgico curativo. A CAAF possibilita uma abordagem pouco invasiva, segura e efectiva, de modo a esclarecer um diagnóstico diferencial exigente.

  13. Providing Meaningful Learning for Students of the Sixth Grade of Middle School: a Study on the Moon Phases. (Breton Title: Propiciando Aprendizagem Significativa Para Alunos do Sexto Ano do Ensino Fundamental: um Estudo sobre as Fases da Lua.) Propiciando el Aprendizaje Significativo Para Alumnos del Sexto Nivel de la Educación General Básica: un Estudio sobre Las Fases de la Luna

    NASA Astrophysics Data System (ADS)

    Darroz, Luiz Marcelo; Samudio Pérez, Carlos Ariel; da Rosa, Cleci Werner; Heineck, Renato

    2012-07-01

    We relate in this article a didactic experience studying the moon phases with a group of middle school students of a private school of the municipality of Passo Fundo, RS. Based on David Ausubel's Meaningful Learning Theory, we have sought to develop a proposal following a didactic model which simulates the phases of the Moon, as based on the previous conceptions of the students. The signs of learning were evidenced by means of memory registries of the activity. From the obtained results we believe that the proposal achieved its goals, since the students were able to identify, differentiate and transfer the phenomenon of the moon phases to new contexts. Thus, it is concluded that a methodology focused on a meaningful content for the students is fundamental to the construction and genuine grasping of what is being learned. Neste artigo, relata-se uma experiência didática de estudo das fases da Lua com uma turma do 6° ano do Ensino Fundamental, de uma escola privada do município de Passo Fundo, RS. Tendo como fundamentação teórica a Teoria da Aprendizagem Significativa de David Ausubel, buscou-se desenvolver a proposta a partir de um modelo didático que simula as fases da Lua e com base nas concepções prévias dos estudantes. Os indícios da aprendizagem foram constatados através de registros de memórias da atividade. Pelos resultados apresentados, acredita-se que a proposta alcançou seus objetivos, uma vez que os estudantes conseguiram identificar, diferenciar e transferir o fenômeno das fases da Lua para novos contextos. Assim, conclui-se que uma metodologia com enfoque em um conteúdo significativo ao estudante é fundamental para a construção e compreensão genuína do que está sendo aprendido. En este artículo se relata una experiencia didáctica de estudio de las fases de la Luna con una clase de 6º año de la educación general básica de una escuela privada del municipio de Passo Fundo, RS. Teniendo como fundamentación teórica la Teor

  14. Vestibular system paresis due to emergency endovascular catheterization.

    PubMed

    Simoceli, Lucinda; Sguillar, Danilo Anunciatto; Santos, Henrique Mendes Paiva; Caputti, Camilla

    2012-04-01

    Objetivo: O objetivo deste relato de caso é descrever uma causa incomum de vestibulopatia periférica associada à perda auditiva unilateral em paciente idoso pós- cateterismo de urgência.Relato de caso: Paciente do gênero masculino, 82 anos, submetido à correção de aneurisma roto de aorta abdominal, no intra-operatório sofreu infarto agudo do miocárdio necessitando de angioplastia primária. Após alta hospitalar refere queixa de hipoacusia acentuada à direita e vertigem incapacitante, sem sinais neurológicos focais. Ao exame clínico otorrinolaringológico apresentava: Teste de Weber lateralizado para a esquerda, nistagmo espontâneo para a esquerda , marcha oscilante, leve disbasia e ataxia, índex-nariz e diadococinesia normais, Teste de Romberg com oscilação sem queda e Fukuda com desvio lateral para a direita. O exame audiométrico evidenciava anacusia à direita e perda neurossensorial à esquerda em agudos, arreflexia vestibular à direita na prova calórica e, na tomografia computadorizada dos ossos temporais e tronco-encefálico, presença de haste metálica atravessando o osso temporal direito, a partir da veia jugular interna e bulbo jugular, atravessando os canais semicirculares posterior, superior e vestíbulo, projetando-se em lobo temporal. O diagnóstico radiológico foi lesão traumática por guia endovascular metálico durante cateterismo de urgência e a conduta, considerando que o paciente não havia compensado o equilíbrio, foi reabilitação vestibular.Conclusão: Queixas de tontura no paciente idoso devem ser criteriosamente avaliadas diante do seu histórico clínico patológico pois os antecedentes de doenças e tratamentos prévios, em geral, direcionam as hipóteses diagnósticas porém podem trazer alterações inesperadas.

  15. Learning about the Sky from the Environment: An Experience Working Along One Year with Students of Elementary Education. (Spanish Title: Aprendiendo sobre EL Cielo Desde el Entorno: Una Experiencia Trabajando Durante un Año Junto a Estudiantes del Primario.) Aprendendo sobre o Céu a Partir do Entorno: Uma Experiência de Trabalho ao Longo de um Ano com Alunos de Ensino Fundamental

    NASA Astrophysics Data System (ADS)

    Longhini, Marcos Daniel; Gomide, Hanny Angeles

    2014-12-01

    percepción limitada que los estudiantes tienen de su alrededor la cual, sin embargo, se expandió debido a las actividades llevadas a cabo, sobre todo en relación con la Luna. Trabajar con medidas sistemáticas revela el manejo cuidadoso de los datos para que sean comprensibles para los estudiantes, así como el trabajo con las sombras para que comprendan primero como se forman estas para después trabajarlas en Astronomía. Por último, llegamos a la conclusión de que el proceso desarrollado consistió en una etapa inicial de una obra que debe ser profundizado en los años posteriores de la formación de estos estudiantes. Projeto de pesquisa desenvolvido com 95 alunos do 6º ano do Ensino Fundamental de uma escola pública estadual de Uberlândia, Minas Gerais. Foi um trabalho contínuo, de fevereiro a dezembro de 2013, o qual levou os alunos a participarem de atividades de observação do entorno, dentre ele, o céu, analisando as mudanças ocorridas. Focamos no estudo das variações de temperaturas, chuvas, duração do dia, variações do tamanho das sombras e mudanças nos aspectos da Lua. Nosso foco de análise centrou-se em discutir os conhecimentos que os referidos alunos tinham acerca dos temas indicados no início e ao término da implementação da proposta. Os resultados mostraram a percepção limitada que os estudantes possuem de seu entorno, todavia, ampliada em função das atividades desenvolvidas, principalmente no que se refere à Lua. O trabalho com medidas sistemáticas revela o cuidado no tratamento dos dados para que eles se tornem compreensíveis aos alunos, assim como o trabalho com as sombras sinaliza para que os alunos primeiramente compreendam como as sombras são formadas para depois trabalhar isso em Astronomia. Por fim, concluímos que o processo vivido constituiu-se em uma etapa inicial de um trabalho que deve ser estimulado para os anos subsequentes da formação desses alunos.

  16. Astronomical Perception of the Secondary School's Students in São Paulo's State School in Suzano City. (Spanish Title: Percepción Astronómica de Alumnos de la Enseñanza Media de la Red Estatal de San Pablo en la Ciudad de Suzano.) Percepção Astronômica de um Grupo de Alunos do Ensino Médio da Rede Estadual de São Paulo da Cidade de Suzano

    NASA Astrophysics Data System (ADS)

    França de Oliveira, Edilene; Voelzke, Marcos Rincon; Amaral, Luis Henrique

    2007-12-01

    año y 20,6% tenían la idea de cuales son los objetos celestes más cercanos de la Tierra. En contraposición, 67,6% clasificaron correctamente el Sol como una estrella; 55,9% relacionaron el Big Bang al origen del Universo; solamente 20,6% identificaron un año-luz como unidad de distancia y 32,4% reconocieron una estrella fugaz como meteoro. El presente análisis fue expandido para otros grupos de la Enseñanza Media, no solamente del período nocturno, sino también diurno de la misma escuela. En esta primera fase se nota el pequeño conocimiento de los alumnos sobre eventos astronómicos y principalmente la gran confusión sobre el significado correcto de los términos astronómicos populares. Embora a Astronomia seja uma das ciências mais antigas da humanidade e muitos dos conceitos astronômicos serem populares, observa-se que uma parcela significativa dos estudantes encontra-se à margem dessas informações. O presente trabalho visa analisar o nível de conhecimento básico dos alunos do Ensino Médio da Rede Estadual da cidade de Suzano quanto aos fenômenos astronômicos que os rodeiam. Para tanto foi elaborado um formulário constando de questões de múltipla escolha, aplicado no primeiro ano noturno da Escola Estadual Batista Renzi. Num espaço amostral de 34 alunos constatou-se que apenas 29,4% compreendiam a sucessão dos dias; 20,6% explicaram corretamente as estações do ano e 20,6% tinham idéia de quais são os objetos celestes mais próximos da Terra. Em contraposição, 67,6% classificaram corretamente o Sol como estrela; 55,9% relacionaram o Big Bang à origem do Universo; apenas 20,6% identificaram um ano-luz como unidade de distância e 32,4% reconheceram uma estrela cadente como meteoro. A presente análise foi expandida para mais 310 alunos de outras classes de Ensino Médio, não somente do período noturno, mas também diurno da mesma escola. Nesta primeira fase nota-se o pequeno discernimento dos alunos sobre eventos astronômicos e

  17. Characterization of Maze Performance in Adrenalectomized Sleep Disrupted Rats: A Comparison of Radial Arm Maze Performance between Adrenalectomized and Sham Adrenalectomized Sleep Disrupted Rats

    DTIC Science & Technology

    2007-01-01

    each of the four final trials. Surgical Protocols 1. Venous jugular catheterization : Following induction an adequate level of anesthesia with IP...sleep disruption performances were compared. In addition, animals were implanted with a venous jugular catheter and sampled over a 36 hour period which...In addition, animals were implanted with a venous jugular catheter, and sampled over a 36 hour period which included 12 hours of baseline, 12

  18. Properties of Interstellar Medium In Infrared-bright QSOs Probed by [O i] 63 um and [C ii] 158 um Emission Lines

    NASA Astrophysics Data System (ADS)

    Zhao, Yinghe; Yan, Lin; Tsai, Chao-Wei

    2016-06-01

    We present a study of the interstellar medium (ISM) in the host galaxies of nine QSOs at 0.1 < z < 0.2 with black hole masses of 3× {10}7 {M}⊙ to 3× {10}9 {M}⊙ based on the far-IR spectroscopy taken with Herschel Space Observatory. We detect the [O i] 63 μm ([C ii] 158 μm) emission in 6 (8) out of 8 (9) sources. Our QSO sample has far-infrared luminosities ({L}{{FIR}}) ˜ several times {10}11{L}⊙ . The observed line-to-{L}{{FIR}} ratios ({L}[{{O}{{I}}]63μ {{m}}}/{L}{{FIR}} and {L}[{{C}{{II}}]}/{L}{{FIR}}) are in the ranges of 2.6 × 10-4 to 10-2 and 2.8 × 10-4 to 2 × 10-3, respectively (including upper limits). These ratios are comparable to the values found in local ULIRGs, but higher than the average value published so far for z\\gt 1 IR-bright QSOs. One target, W0752+19, shows an additional broad velocity component (˜720 km s-1) and exceptionally strong [O i] 63 μm emission with {L}[{{O}{{I}}]63μ {{m}}}/{L}{{FIR}} of 10-2, an order of magnitude higher than the average value found among local (U)LIRGs. Combining with the analyses of the Sloan Digital Sky Survey optical spectra, we conclude that the [O i] 63 μm emission in these QSOs is unlikely excited by shocks. We infer that the broad [O i] 63 μm emission in W0752+19 could arise from the warm and dense ISM in the narrow-line region of the central active galactic nucleus. Another possible explanation is the existence of a dense gas outflow with {n}{{H}}˜ {10}4 cm-3, where the corresponding broad [C ii] emission is suppressed. Based on the far-IR [O i] and [C ii] line ratios, we estimate constraints on the ISM density and UV radiation field intensity of {n}{{H}}≲ {10}3.3 cm-3 and {10}3\\lt {G}0≲ {10}4.2, respectively. These values are consistent with those found in local Seyfert 1 ULIRGs. In contrast, the gas with broad velocity width in W0752+19 has {n}{{H}}≳ {10}4.3 cm-3 and {G}0\\gt {10}4. Herschel is an ESA space observatory with science instruments provided by European-led Principal Investigator consortia and with important participation from NASA.

  19. Comparing the use of 4.6 um lasers versus 10.6 um lasers for mitigating damage site growth on fused silica surfaces

    SciTech Connect

    Yang, S T; Matthews, M J; Elhadj, S; Cooke, D; Guss, G M; Draggoo, V G; Wegner, P J

    2010-10-21

    The advantage of using mid-infrared (IR) 4.6 {micro}m lasers, versus far-infrared 10.6 {micro}m lasers, for mitigating damage growth on fused silica is investigated. In contrast to fused silica's high absorption at 10.6 {micro}m, silica absorption at 4.6 {micro}m is two orders of magnitude less. The much reduced absorption at 4.6 {micro}m enables deep heat penetration into fused silica when it is heated using the mid-IR laser, which in turn leads to more effective mitigation of damage sites with deep cracks. The advantage of using mid-IR versus far-IR laser for damage growth mitigation under non-evaporative condition is quantified by defining a figure of merit (FOM) that relates the crack healing depth to laser power required. Based on our FOM, we show that for damage cracks up to at least 500 {micro}m in depth, mitigation using a 4.6 {micro}m mid-IR laser is more efficient than mitigation using a 10.6 {micro}m far-IR laser.

  20. Mild steels coated with 14% manganese covered electrodes (E7-UM-200-K and E1-UM-350): Phenomena at the steel-coating interface

    SciTech Connect

    Molleda, F. . E-mail: fmolleda@etsin.upm.es; Mora, J.; Molleda, F.J.; Carrillo, E.; Mora, E.; Mellor, B.G.

    2006-12-15

    In this work the authors have studied the phenomena in the interface of the coating made on soft carbon steel with electrodes with a high content of manganese. The study has been done with scanning electron microscope and X-rays mapping images. These images show how the alloy elements are distributed in each of the constituent elements presented in the interface, and the nature of these constituents. These results have allowed us to verify that many of the problems that arise in homogeneous joints, as such localised corrosion, low interface resistance, etc., happened, precisely in these regions. As a help to determine the nature of the constituent elements, microhardness measurements have also been made.

  1. Retained Textile Foreign Bodies: Experience of 27 Years.

    PubMed

    Arikan, Soykan; Kocakusak, Ahmet

    2015-01-01

    Introdução e Objetivos: A retenção de materiais têxteis após a cirurgia é uma situação indesejada, tanto para o doente como para o cirurgião. Frequentemente são subnotificados por questões de natureza médico-legal. Apresentamos 14 casos de textilomas (compressoma) que foram tratados ou seguidos pessoalmente por dois cirurgiões gerais num período de 27 anos para descrever e definir as características clínicas e patológicas. Material e Métodos: Foram avaliados retrospectivamente os dados relativos a uma serie de casos, nomeadamente: características dos doentes (sexo e idade), localização anatómica do corpo estranho, intervalo de tempo até ao diagnóstico, apresentação clínica, queixas, abordagem diagnóstica, motivo de cirurgia, tipo de tratamento cirúrgico e complicações. Resultados: Foram identificados nove doentes do sexo feminino e cinco do sexo masculino, com uma média de idades de 43,07 ± 15,23 (mediano: 45) anos para o momento do diagnóstico. Em três doentes a cirurgia prévia foi cesariana, em quatro casos herniorrafia inguinal, um doente submetido a laparotomia exploradora por abdome agudo, um doente no qual foi realizado uma sigmoidectomia, uma doente submetida a apendicectomia e salpingooforectomia direita, uma doente na qual a cirurgia anterior tinha sido para corrigir uma hérnia incisional após laparotomia por neoplasia do ovário, um caso de tiroidectomia total, uma herniorrafia por hérnia epigástricae uma doente submetida cirurgia conservadora bilateral da mama com pesquisa de gânglio sentinela. A localização mais frequente dos compressomas foi intra-abdominal em sete casos, em quatro doentes a localização foi inguinal, um caso localizado na incisão da correcção da hérnia epigástrica, um doente com textiloma na loca de tiroidectomia, e no caso da doente submetida a cirurgia conservadora da mama em ambas regiões axilares se encontraram corpos estranhos/compressomas. O intervalo de tempo foi em média14

  2. [Esophageal perforation in children: a review of one pediatric surgery institution's experience (16 years)].

    PubMed

    Vieira, Elizabete; Cabral, Maria João; Gonçalves, Mroslava

    2013-01-01

    Introdução: O estudo teve por objetivo avaliar a experiência do nosso Serviço no tratamento das perfurações esofágicas. Material e Métodos: Análise retrospetiva de nove casos ocorridos entre 1 de Janeiro de 1996 e 31 de Dezembro de 2011. Destes casos, sete ocorreram após ingestão acidental de corpos estranhos e em dois tratou-se de lesões iatrogénicas após dilatação esofágica: por estenose péptica num caso e no outro por estenose da anastomose esofágica término-terminal de uma criança operada por atrésia do esófago. Resultados: Em 78% dos casos a abordagem inicial foi médica, com encerramento comprovado da perfuração em média ao fim de 20 dias; 22% dos doentes (dois casos) foram submetidos a cirurgia sem sucesso, acabando um deles por curar sem sequelas com pausa alimentar e terapêutica médica; no outro caso verificou-se necessidade de realizar posteriormente uma esofagocoloplastia. Na nossa série não se registou mortalidade. Discussão: A perfuração esofágica é uma das lesões mais graves do trato alimentar, continuando a ser devastadora, e, de difícil diagnóstico e tratamento. O reconhecimento desta complicação é fundamental para o seu tratamento com sucesso. Conclusões: O atraso do diagnóstico está associado a uma mortalidade que pode oscilar entre os 20 e 40%.

  3. VizieR Online Data Catalog: NGC 891 70-500um images (Hughes+, 2014)

    NASA Astrophysics Data System (ADS)

    Hughes, T. M.; Baes, M.; Fritz, J.; Smith, M.; Parkin, T.; Gentile, G.; Bendo, G.; Wilson, C.; Allaert, F.; Bianchi, S.; De Looze, I.; Verstappen, J.; Viaene, S.; Boquien, M.; Boselli, A.; Clements, D.; Davies, J.; Galametz, M.; Madden, S.; Remy-Ruyer, A.; Spinoglio, L.

    2014-02-01

    We present new, reduced Herschel Space Observatory PACS and SPIRE 70, 160, 250, 350, and 500 micron observations of NGC 891 taken has part of the Very Nearby Galaxy Survey (P.I.: C. Wilson) and an additional PACS 100 micron image taken from the Herschel EDGE-on galaxy Survey (P.I.: E. Murphy). The PACS 70, 100 and 160 observations were reduced with the Herschel Interactive Processing Environment (HIPE) v.11.0.1 with PACS Calibration v.32 and Scanamorphos v.22.0 (Roussel, 2013PASP..125.1126R). The SPIRE 250, 350, and 500 micron observations data were reduced with HIPE v.11.0.12 including the latest calibration due for inclusion in HIPE v.12.0 (Bendo et al., 2013MNRAS.433.3062B), and BriGAdE (Smith, in preparation). Complete details on the data reduction may be found in the paper. Image properties are summarised in images.dat. Please note that the FITS images presented here do not include the calibration factors to account for extended sources, nor colour corrections as described in the paper. The raw data can be retrieved from the Herschel Science Archive (ESA). (2 data files).

  4. "I May Be Crackin', But Um Fackin": Racial Humor in "The Watsons Go To Birmingham--1963"

    ERIC Educational Resources Information Center

    McNair, Jonda C.

    2008-01-01

    This article examines the utilization of racial humor in Christopher Paul Curtis' novel, "The Watsons Go To Birmingham--1963." The theoretical perspectives that inform the analysis include critical race theory and humor theory. The results of the analysis reveal that the use of humor in this book is influenced to a significant degree by race and…

  5. VizieR Online Data Catalog: WISE and HIP 22um excess stars (Wu+, 2013)

    NASA Astrophysics Data System (ADS)

    Wu, C.-J.; Wu, H.; Lam, M.-I.; Yang, M.; Wen, X.-Q.; Li, S.; Zhang, T.-J.; Gao, L.

    2013-11-01

    In this paper, we present a catalog that includes 141 bright candidates (<=10.27mag, V band) showing an excess of infrared (IR) at 22μm. Of these 141 candidates, 38 stars are known IR-excess stars or disks, 23 stars are double or multiple stars, and 4 are Be stars while the remaining more than 70 stars are identified as 22 μm excess candidates in our work. The criterion for selecting candidates is Ks-[22]μm. All these candidates are selected from the Wide-field Infrared Survey Explorer all-sky data cross-correlated with the Hipparcos main catalog and the likelihood-ratio technique is employed. Considering the effect of background, we introduce the IRAS 100μm level to exclude the high background. We also estimate the coincidence probability of these sources. In addition, we present the optical to mid-IR spectral energy distributions and optical images for all the candidates, and give the observed optical spectra of six stars with the National Astronomical Observatories, Chinese Academy of Sciences' 2.16m telescope. To measure for the amount of dust around each star, the fractional luminosity is also provided. We also test whether our method of selecting IR-excess stars can be used to search for extra-solar planets; we cross-match our catalog with known IR-excess stars with planets but found no matches. Finally, we give the fraction of stars showing excess IR for different spectral types of main-sequence stars. (2 data files).

  6. U.S. Court of Claims Deposition of Kish um us tubbee. Teaching with Documents.

    ERIC Educational Resources Information Center

    Blondo, Richard A.; And Others

    1994-01-01

    Discusses the expulsion of the Choctaw Indians from their lands in the U.S. southeast as a result of the Indian Removal Act of 1830. Provides a lesson plan using a primary source document along with accompanying discussion questions. Includes a three-page letter that is the deposition of a Choctaw Indian protesting removal. (CFR)

  7. VizieR Online Data Catalog: AGN 2.5-11um spectroscopy (Clavel+, 2000)

    NASA Astrophysics Data System (ADS)

    Clavel, J.; Schulz, B.; Altieri, B.; Barr, P.; Claes, P.; Heras, A.; Leech, K.; Metcalfe, L.; Salama, A.

    2000-03-01

    We present observations over the 2.5-11μm range, with the ISOPHOT-S spectrometer and the ISOCAM imaging camera, of a sample of 57 AGNs and one non-active SB galaxy. The sample is about equally divided into type I (<=1.5 28 sources) and type II (>1.5 29 sources) objects. (4 data files).

  8. CSHELL: a high spectral resolution 1-5 um cryogenic echelle spectrograph for the IRTF

    NASA Astrophysics Data System (ADS)

    Greene, Thomas P.; Tokunaga, Alan T.; Toomey, Douglas W.; Carr, Jonathan B.

    1993-10-01

    A 1 - 5.4 micrometers Cryogenic Echelle Spectrograph (CSHELL) for the NASA Infrared Telescope Facility is described. It achieves a resolving power of 5,000 to 40,000 using slits ranging from 4.0' to 0.5' in width and 30' long. It operates in a single-order long-slit mode, and a circular variable filter is used as an order sorter. Two infrared arrays are employed to achieve spectral coverage from 1 - 5.4 micrometers : a 256 X 256 HgCdTe NICMOS-3 array for 1 - 2.5 micrometers and a SBRC 58 X 62 InSb array for 2.8 - 5.4 micrometers . A closed- cycle cooler is employed to keep the optics and supporting structure at 73 K and to maintain the detectors at their proper operating temperatures. The entire spectrograph fits within an envelope of 64 cm X 35 cm X 27 cm. The instrument is controlled by a microcomputer mounted on the telescope, but the observer commands the instrument from a UNIX X Windows workstation on the Internet. This use of the Internet for communication between instrument control and user interface computers facilitates remote observing. A limiting magnitude of 12.3 mag is achieved for S/N equals 10 in 1 hour integration time, at resolving power of 20,000 at 2.2 micrometers wavelength.

  9. A Room-Temperature Semiconductor Spaser Operating Near 1.5 um

    DTIC Science & Technology

    2011-04-22

    optical phenomena by plasmonic nanocavity gratings,” Nano Lett. 10(12), 4880–4883 (2010). 4. D . E. Chang, A. S. Sorensen, E. A. Demler, and M. D ...2010). 6. D . J. Bergman and M. I. Stockman, “Surface plasmon amplification by stimulated emission of radiation: quantum generation of coherent...waveguides,” Opt. Express 15(3), 1211–1221 (2007). 16. M. Bahriz, V. Moreau, J. Palomo, R. Colombelli, D . A. Austin, J. W. Cockburn, L. R. Wilson, A. B. Krysa

  10. VizieR Online Data Catalog: Chamaeleon III 870um sources maps (Belloche+, 2011)

    NASA Astrophysics Data System (ADS)

    Belloche, A.; Parise, B.; Schuller, F.; Andre, P.; Bontemps, S.; Menten, K. M.

    2011-06-01

    The 870 micron dust continuum emission map of the Chamaeleon III molecular cloud displayed in Fig. 2 is available at CDS in FITS format. The data were obtained with the bolometer camera LABOCA at the APEX telescope. They were calibrated, reduced, co-added, gridded, smoothed to an effective angular resolution of 21.2" (FWHM), and written in FITS format with the BoA software. The flux density unit is Jy/21.2"-beam. The coordinates are equatorial (J2000) and the offsets are in RADIO projection. (1 data file).

  11. Peculiarities of coagulation action of IR lasers (1-3 um) radiation on cornea

    NASA Astrophysics Data System (ADS)

    Berezin, Yuri D.; Boiko, Ernest V.; Volkov, Venjamin V.; Danilichev, Vladimir F.; Ganin, Dmitry V.; Gatzu, Andrey F.; Smirnov, Nicolay N.; Lazo, Victor V.; Tkachuk, Alexandra M.

    1996-04-01

    Antiviral, antibacterial, antitumoral effects of laser coagulation are now of great importance in clinical ophthalmology for different corneal diseases treatment. One can note, that nowadays solid-state free-mode pulsed near-and-mid-infrared lasers with the 1.3 - 3.0 micrometers wavelengths may become widespreadly accepted in this field of ophthalmosurgery. The corneal tissue absorption coefficients for these wavelengths are lying from some parts to several thousand cm-1. Thus, by proper selection of laser wavelength, possibility is appeared to coagulate precisely the seat of pathological alterations without damaging of more deeper, non changed corneal tissue. In our work the comparative experimental study results of rabbit cornea coagulation after exposure with using of different IR lasers (with 1.32; 1.54; 1.96; 2.09 and 2.84 micrometers wavelengths) are presented. Pulse duration was about 10-3 s. The subthreshold, threshold and superthreshold energy levels were studied. Threshold energies were registered if slightly noticed coagulative changes appeared in exposed volume of corneal tissue. The cornea response resulting from laser radiation exposure was evaluated by clinical examination, slit lamp biomicroscopy, light microscopy, fluorescent staining and biochemistry. For all wavelengths initial damage was found within the cornea layers. Superthreshold injury revealed the same picture except that for 1.32 micrometers the threefold increase of the threshold energy caused additionally iris injury. The damages of the cornea were marked near the surface, stretched to more deeper layers, and damage zones were extended from the epithelium for 2.84 micrometers wavelength to whole cornea thickness for 1.32 and 1.54 micrometers wavelengths and have intermediate position for 1.96 and 2.09 micrometers wavelengths, depending on the corneal absorption coefficient. Quantitative results of threshold energy levels were calculated by probit-analysis. The radiant exposure (HD50), that cause the threshold coagulation changes in cornea with 50% probability was determined for the beam diameter (irradiance diameter) of 2 mm and for 1.32; 1.54; 1.96; 2.09 and 2.84 micrometers wavelengths. Values determined were (2.4 +/- 0.2) X 10; 7.2 +/- 0.6; 2.9 +/- 0.5; 3.7 +/- 0.2; (1.9 +/- 0.4) X 10-1 J/cm2. These values are well-correlated to corneal absorption coefficients. The absorption coefficient the higher, the value HD50 the lower and the `danger' for ocular structures damage also the lower. This fact is needed to be taken into account, because of normative documents did not reflect it in 1.3 - 3.0 micrometers wavelength range. The obtained results may be used for development of new clinical laser applications and refinement of the laser safety standards.

  12. Fracture analysis and its relation to radioactivity around Gebel Um Risha, south eastern desert, Egypt

    NASA Astrophysics Data System (ADS)

    El Khateeb, S. O.; El Akraby, A. M.

    1994-07-01

    Analysis of radioactive fracture patterns prevailing in the study area revealed that there are a number of tectonic trends which show abnormal radioactivity. These trends can be arranged according to the degree of their importance as NW, NE, EW and NS. Meanwhile, they are applied in delineating interesting structural features that may serve as favourable loci of economic radioactive mineral deposits. Correlation of these radioactive fracture patterns with those deduced from surface geological map of the study area exhibits a good agreement assuring the importance of aeroradiometric survey data as an excellent tool in structural mapping.

  13. Optical detector selection for 1.5-um KTP OPO atmospheric lidar

    NASA Astrophysics Data System (ADS)

    Mamidipudi, Priyavadan; Killinger, Dennis K.

    1999-05-01

    A 1.5 micron wavelength KTP OPO Lidar system has been developed and used to study the sensitivity and the system signal-to-noise ratio for hard target and atmospheric aerosol lidar returns. Optimization of the receiver system was studied that included the use of different sizes, types of detectors, and the effect of laser beam quality factor, M2, on the telescope overlap function. Detectors that were studied included several different sizes of InGaAs APDs, direct photodetectors, a transferred-electron intensified photodiode (TE-IPD), and a PMT. The influence of the diffraction or beam quality factor (M2) of the OPO laser was studied and found to have a significant influence on the overlap of the transmit and receiver field of view. This overlap function is also influenced by the size of the lidar detector since a large M2 value can overfill the detector/telescope field of view so that small (high speed) detectors may be subject to a large reduction in the lidar signal. The size of the photodiodes and APDs used in the initial OPO lidar experiments were of the order of 0.1 mm to 2 mm, while the TE-IPD and the PMT are larger in acceptance area. Some initial experimental measurements with the photodetectors and APD, and projected theoretical comparisons with the TE-IPD and PMT detectors have been made.

  14. VizieR Online Data Catalog: Dimethyl sulfide laboratory um, mm & FIR spectra (Jabri+, 2016)

    NASA Astrophysics Data System (ADS)

    Jabri, A.; Nguyen, H. V. L.; Mouhib, H.; Tchana, F. K.; Manceron, L.; Stahl, W.; Kleiner, I.

    2016-02-01

    DMS was purchased from Alfa Aesar GmbH & Co KG, Karlsruhe, Germany and used without further purification. The microwave spectrum was measured in the frequency range 2-40GHz using two Molecular Beam Fourier Transform MicroWave (MB-FTMW) spectrometers in Aachen, Germany. The millimeter spectrum was recorded in the 50-110GHz range. The FIR spectrum was measured for the first time at high resolution using the FT spectrometer and the newly built cryogenic cell at the French synchrotron SOLEIL. (3 data files).

  15. New semiconductor diode laser emitting at 2 um for microsurgery applications

    NASA Astrophysics Data System (ADS)

    Gobbi, Pier Giorgio; Ragazzi, D.; Azzolini, Claudio; Trabucchi, Giuseppe; Brancato, Rosario

    1996-01-01

    A surgical laser instrument is presented, based on a semiconductor diode emitting in the spectral region around 2 micrometer, in continuous mode. At this wavelength tissue absorption is via histological water, and the interaction is purely thermal. A portable laser station was built, emitting up to 250 mW of optical power at 1.94 micrometers, out of the tip of a low- hydroxil fused-silica optical fiber of 200 micrometer diameter. Experiments have been performed both in vitro with enucleated porcine eyes and in vivo, on rabbits and rats. In vitreo-retinal surgery, retinectomies and incisions of epiretinal fibrotic membranes have been achieved. At reduced output power the laser radiation has been applied to the welding of tissues, in particular cornea, sclera and skin, with interesting results. This new laser source, characterized by ergonomic advantages like compactness, portability, long lifetime, reduced maintenance, is potentially attractive for a number of microsurgical procedures like micro- incisions, shallow coagulations, and welding of hydrated biological membranes.

  16. Development of a 2.8 um film for scientific balloons

    NASA Astrophysics Data System (ADS)

    Yamagami, T.; Isas/Jaxa Balloon Team

    Development of a balloon flying at higher altitudes is one of the most attractive trials in scientific balloon technologies. In 2002, the ISAS balloon group have succeeded in flying a balloon up to the altitude of 53.0 km using a balloon with a volume of 60,000 m^3 made of an ultra-thin polyethylene film with a thickness of 3.4 μm. To go to higher altitudes, it is necessary to make the balloon film much lighter. We started to develop the thinnest film within the current technology. We have made a special die for molding a thin polyethylene film, and formed a film with a thickness of 3.0 μm and a width of 110 cm. Using this film, we have manufactured a balloon with 5,000 m^3 in volume and succeeded in flying the balloon up to an altitude of 47.1 km. Then, we tried to make a thinner film changing the resin density and succeeded in forming a film with a thickness of 2.8 μm and a width of 140 cm. We are going to perform a balloon experiment in this early summer. In this paper, our approach to the 2.8 μm film and the result of the balloon experiment will be described.

  17. Isolation of UmRrm75, a gene involved in dimorphism and virulence of Ustilago maydis

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Ustilago maydis displays dimorphic growth, alternating between a saprophytic haploid yeast form and a filamentous dikaryon, generated by mating of haploid cells and which is an obligate parasite. Induction of the dimorphic transition of haploid strains in vitro by change in ambient pH has been used...

  18. Matching of Bragg condition of holographic phase gratings in 1.3-1.5um region

    NASA Astrophysics Data System (ADS)

    Silvennoinen, Raimo V. J.; Hamalainen, Rauno M.

    1991-10-01

    The spectral diffraction efficiency of phase holograms depends on refractive index modulation, grating spacing, and the thickness of a holographic grating, e.g., the refractive index modulation of the dichromatic gelatin grating (DCG) can be increased so that the diffraction efficiency of 90% measured in Bragg angle without refractive index matching can be achieved in the recording wavelength. The use of the same holographic grating in longer wavelength regions in accordance with the Bragg condition demands the refractive index matching. In our applications, holographic phase gratings in hololens form (HOL) are used as a wavelength selective elements in conventional optical multi-/demultiplexing (mux/demux) applications, where various wavelengths are multiplexed to the detectors needed. On the other hand, the novel applications of the HOL element used as a monochromator in the external cavity construction of a semiconductor laser according to the refractive index matching the Bragg condition are theoretically investigated in the wavelength region from 1.3 micrometers to 1.5 micrometers .

  19. Porcine dermal lesions produced by 1.3um laser pulses

    NASA Astrophysics Data System (ADS)

    Johnson, Thomas E.; Winston, Golda C. H.; Burton, Margaret B.; Greene, Willie L.

    2003-07-01

    An increasing number of industries, to include military, medicinal, and technological arenas, are using 1.3 micron laser systems for which current skin and eye guidelines are identical. No skin threshold, ED50 or exposure data are available. The mechanisms of laser-tissue interaction with skin at 1.3 microns are unknown. Together, these facts necessitate increased research to prevent future laser accidents and injuries. This study examines the method of interaction of 1.3 microns laser light with tissue in the Yorkshire pig. Our research addresses laser-tissue interaction through delivery using a Nd:YAG with an intracavity filter producing 1.3 micron light at 0.5 millisecond exposure time and in the range of 137 to 475 J/cm2. Laser exposure to Yorkshire pigs was evaluated for dermal lesion development. Lesions were appraised for acute, one-hour and 24-hour post exposure presentation.

  20. Application of 2-um wavelength holmium lasers for treatment of skin diseases

    NASA Astrophysics Data System (ADS)

    Shcherbakov, Ivan A.; Klimov, Igor V.; Tsvetkov, Vladimir B.; Nerobeev, Alexander I.; Sadovnikova, Lija B.; Eliseenko, Vladimir I.

    1994-09-01

    Theoretical and experimental analysis of the efficiency of application of 2 micrometers pulsed holmium laser for cosmetic and plastic surgery and dermatology is carried out. Preliminary experiments were carried out on rats. Solid state 2 micrometers pulsed laser was allowed to operate in free running mode with pulse energy up to 1.5 J and pulse repetition rate up to 5 Hz. To deliver emission to the object a flexible quartz fiber without further focusing of 2.5 m in length and 400 micrometers of the core diameter was used. The effect of the different power density emission on the skin was studied. The second stage was the study of the influence of 2 micrometers emission on human skin. The results of the removal of hemangioma, papilloma, telangiectasia, nevus, nevus acantholytic, xanthelasma palpebral, verruca, chloasma, pigmental spots, tattoos, etc. are presented. Precision, simplicity, efficiency, and the high cosmetic effect of these operations is noted.

  1. VizieR Online Data Catalog: Chamaeleon I 870um sources (Belloche+, 2011)

    NASA Astrophysics Data System (ADS)

    Belloche, A.; Schuller, F.; Parise, B.; Andre, P.; Hatchell, J.; Jorgensen, J. K.; Bontemps, S.; Weiss, A.; Menten; K. M.; Muders, D.

    2011-01-01

    Table 2 lists the sources extracted with GAUSSCLUMPS from the filtered 870 micron continuum emission map of Chamaeleon I obtained with the bolometer camera LABOCA at the APEX telescope. These sources are listed in the order in which they were found by GAUSSCLUMPS, i.e. roughly in order of decreasing peak flux density. The 870 micron dust continuum emission map of the Chamaeleon I molecular cloud is available in FITS format. The data were obtained with the bolometer camera LABOCA at the APEX telescope. They were calibrated, reduced, co-added, gridded, smoothed to an effective angular resolution of 21.2" (FWHM), and written in FITS format with the BoA software. The flux density unit is Jy/21.2"-beam. The coordinates are equatorial (J2000) and the offsets are in RADIO projection. (6 data files).

  2. Infrared 3-4 um Spectroscopic Investigation of a Large Sample of Nearby Ultraluminous Infrared Galaxies

    DTIC Science & Technology

    2005-09-27

    servable with small air masses from Mauna Kea , Hawaii, our main observing site. These selection criteria result in 24 ULIRGs classified optically as... Observatory , 2-21-1, Osawa, Mitaka, Tokyo 181-8588, Japan; masa.imanishi@nao.ac.jp C. C. Dudley Naval Research Laboratory, Remote Sensing Division...data collected at Subaru Telescope, which is operated by the National Astronomical Observatory of Japan. 2 Visiting Astronomer at the Infrared Telescope

  3. "Um, They Weren't Thinking about Their Thinking": Children's Talk about Issues of Oppression

    ERIC Educational Resources Information Center

    Fain, Jeanne Gilliam

    2008-01-01

    This article presents first and second grade children's talk about issues of language diversity and culture. Children focus on the issue of oppression and initially examine oppressors in their talk within literature circles across a year in a Sheltered English Immersion classroom. Drawing on a critical literacy framework and anti-bias perspective,…

  4. 250 um inner diameter hollow waveguide for Er:YAG laser radiation

    NASA Astrophysics Data System (ADS)

    Němec, Michal; Jelínková, Helena; Miyagi, Mitsunobu; Iwai, Katsumasa; Matsuura, Yuji

    2009-02-01

    Advanced application of Er:YAG laser radiation in medical treatment requires a suitable, very precise delivery of this light to a target. In some cases (urology, cardiology, or endodontic treatments), thin waveguides are needed. Therefore a preliminary investigation was conducted with 250/360 μm inner/outer diameter hollow glass waveguides. The waveguide has inner coating made from cyclic olefin polymer and silver layers. All delivery systems were simple and consisted of lens, protector, and the waveguide. The laser source was the Er:YAG system working in a free-running regime and generating radiation at 2.94 μm wavelength. For testing, output laser energy up to 100 mJ with a repetition rate of 1 Hz was chosen. The output laser spatial profile was approximately TEM00 mode, so the structure changes behind the delivery system were readily detected. The energy delivery characteristics were also checked, and the transmission reached 77%. The maximum input fluence into the waveguide was 200 mJ/cm2, and no significant damages to waveguides were observed after the measurements.

  5. Distribution of benthic foraminifers (>125 um) in the surface sediments of the Arctic Ocean

    USGS Publications Warehouse

    Osterman, Lisa E.; Poore, Richard Z.; Foley, Kevin M.

    1999-01-01

    Census data on benthic foraminifers (>125 ?m) in surface sediment samples from 49 box cores are used to define four depth-controlled biofacies, which will aid in the paleoceanographic reconstruction of the Arctic Ocean. The shelf biofacies contains a mix of shallow-water calcareous and agglutinated species from the continental shelves of the Beaufort and Chukchi Seas and reflects the variable sedimentologic and oceanic conditions of the Arctic shelves. The intermediate-depth calcareous biofacies, found between 500 and 1,100 meters water depth (mwd), contains abundant Cassidulina teretis , presumably indicating the influence of Atlantic-derived water at this depth. In water depths between 1,100 and 3,500 m, a deepwater calcareous biofacies contains abundant Oridorsalis umbonatus . Below 3,500 mwd, the deepwater mixed calcareous/agglutinated biofacies of the Canada, Makarov, and Eurasian Basins reflects a combination of low productivity, dissolution, and sediment transport. Two other benthic foraminiferal species show specific environmental preferences. Fontbotia wuellerstorfi has a depth distribution between 900 and 3,500 mwd, but maximum abundance occurs in the region of the Mendeleyev Ridge. The elevated abundance of F. wuellerstorfi may be related to increased food supply carried by a branch of Atlantic water that crosses the Lomonosov Ridge near the Russian Continental Shelf. Triloculina frigida is recognized to be a species preferring lower slope sediments commonly disturbed by turbidites and bottom currents. INTRODUCTION At present, our understanding of the Arctic Ocean lags behind our understanding of other oceans, and fundamental questions still exist about its role in and response to global climate change. The Arctic Ocean is particularly sensitive to climatic fluctuations because small changes in the amounts of sea-ice cover can alter global albedo and thermohaline circulation (Aagaard and Carmack, 1994). Numerous questions still exist regarding the nature and timing of paleoclimatic events in the Arctic Ocean. In order to attempt to answer some of these questions, baseline studies are imperative. This report discusses the distribution of benthic foraminifers in surface sediment samples from 49 box cores (figs. 1 and 2, table 1) collected by the U.S. Geological Survey (USGS) with the assistance of the U.S. Coast Guard (USCG). A modern data set of benthic foraminiferal distribution is necessary for interpreting the paleoclimatic and oceanographic history of the Arctic Ocean.

  6. Alors...euh...on parle francais? (So...um...Shall We Speak French?)

    ERIC Educational Resources Information Center

    Frommer, Judith G.; Ishikawa, Wayne

    1980-01-01

    Describes a one-semester conversational course taught at Harvard University designed to teach basic oral communication skills in French with the main emphasis on teaching students to pause while speaking. (AM)

  7. Single-mode planar optics for 4-20um wavelengths astronomical interferometry

    NASA Astrophysics Data System (ADS)

    Laurent, E.; Kern, P.; Schanen, I.; Rousselet-Perraut, K.

    2002-06-01

    Single-mode planar optics for 4-20 micrometers wavelengths astronomical interferometry. Spatial filtering is a critical issue to achieve nulling interferometry in the framework of spatial missions aimed at the detection of exoplanets. Several working interferometric instruments take benefits of guided optics for spatial filtering in the near IR wavelengths and thus provide accurate visibility measurements. Futhermore planar optics would also provides beam combining functions within a single compact and stable device. Existing telecom technology allows beam combiner realizations for 0.8 to 1.6 micrometers wavelengths. Last works allow us to valid these technologies up to 2.4 micrometers for stellar interferometry in the H and K bands. Technological developments are required to meet the scientific domain of the spatial missions like IRSI/DARWIN and TPF dedicated to thermal infrared wavelengths [4-20 micrometers]. We present the most promising materials with their technologies to manufacture single-mode planar optics for this wavelength range. First set of solutions involved chalcogenide glasses. Channel waveguides could be manufactured by photo-exposition method or thin layer etching process. Another solution is using porous silicon obtained from an acid dissolution of a silicon substrate which allows refractive index modulation. The last set of solution is based on thin films etching of semiconductor materials like silicon, germanium, zinc sulfide and zinc selenide.Test benches for the single-mode behavior are also presented. For each solutions, we present some manufactured waveguides with their optical characterizations.

  8. [The life story of Joaquim Alberto Cardoso de Melo: Quincas, Um berro à vida].

    PubMed

    Zancan, Lenira; Matida, Álvaro Hideyoshi

    2015-10-01

    The article seeks to reflect on the contribution of Joaquim Alberto Cardoso de Melo (1936-1993) to the field of public health relating his life story and his scientific production with core issues of education and health, present in his time and which remain in debate to this day. His contribution resulted in the production of new meanings for health practices, with the understanding as social and transdisciplinary phenomena. Based on conversations with co-authors and friends and rereading of his texts, it was decided to approach his biography from: (i) his skills and participation in initiatives and practices of preventive medicine and popular education, which fomented the critical analysis of health education; (ii) his presence as an educator in public health courses throughout the country, eliciting the deconstruction of the theories and practices of education and health with managers, students, professionals and teachers; (iii) his availability for transdisciplinary dialogue with the humanities and social sciences in the search for "epistemological sutures" between reason and passion, capable of responding to the dilemmas and challenges of healthcare work. These three trajectories indicate that the performance of "Quincas" must be understood from his restlessness as a health professional and educator, engaged in the production of knowledge and practices related to the complexity of the phenomenon of life.

  9. Teaching Advanced Concepts in Computer Networks: VNUML-UM Virtualization Tool

    ERIC Educational Resources Information Center

    Ruiz-Martinez, A.; Pereniguez-Garcia, F.; Marin-Lopez, R.; Ruiz-Martinez, P. M.; Skarmeta-Gomez, A. F.

    2013-01-01

    In the teaching of computer networks the main problem that arises is the high price and limited number of network devices the students can work with in the laboratories. Nowadays, with virtualization we can overcome this limitation. In this paper, we present a methodology that allows students to learn advanced computer network concepts through…

  10. Earth's spectral albedo from 0.5 to 4.4 um

    NASA Astrophysics Data System (ADS)

    Montanes-Rodrig, P.; Palle, E.; Goode, P. R.; Koonin, S. E.

    2005-12-01

    We have analyzed spectroscopic earthshine data to determine Earth's nightly spectral albedos covering the visible, near and middle infrared spectral ranges. Observations in the visible were undertaken from Palomar Observatory with the spectrograph in the Palomar 60" telescope and with the echelle spectrograph of the InfraRed Telescope Facility (IRTF) on Mauna Kea in Hawaii. The observing runs were chosen near the quarter moon to reduce the background glow produced by the moonshine (bright side of the Moon). Although observations were taken on different nights, the similarity of lunar phases and comparable cloud cover conditions for the monitored part of the Earth's surface, allow us to derive, for the first time, an apparent albedo of the Earth covering the entire spectral range from 0.5 to 4.4 microns.

  11. Educacao Fisica Escolar: A Construcao de um Conceito (School Physical Education: The Construction of a Concept).

    ERIC Educational Resources Information Center

    Colpas, Ricardo Ducatti

    2000-01-01

    Seeks to understand school physical education praxis in light of the human development theories of Lev Vygotsky. Develops a methodology of teaching and a conception of learning that enables students to recognize physical education as a school discipline connected to a dynamic curriculum. (BT)

  12. VizieR Online Data Catalog: MIPS 24um calibrators (Engelbracht+, 2007)

    NASA Astrophysics Data System (ADS)

    Engelbracht, C. W.; Blaylock, M.; Su, K. Y. L.; Rho, J.; Rieke, G. H.; Muzerolle, J.; Padgett, D. L.; Hines, D. C.; Gordon, K. D.; Fadda, D.; Noriega-Crespo, A.; Kelly, D. M.; Latter, W. B.; Hinz, J. L.; Misselt, K. A.; Morrison, J. E.; Stansberry, J. A.; Shupe, D. L.; Stolovy, S.; Wheaton, W. A.; Young, E. T.; Neugebauer, G.; Wachter, S.; Perez-Gonzalez, P. G.; Frayer, D. T.; Marleau, F. R.

    2014-07-01

    The data were all obtained using the MIPS small-field photometry mode astronomical observation template (AOT). For most targets, two cycles of photometry using 3s exposures were obtained, resulting in 14 individual images at each of two telescope nod positions (excluding the short exposure that starts the data-taking sequence at each of the two telescope nod positions). Starting with the raw data downloaded from the Spitzer Science Center (SSC), these data were processed using version 3.06 of the MIPS Data Analysis Tool (DAT; Gordon et al., 2005PASP..117..503G), which performs standard processing of infrared detector array data (slope fitting, dark subtraction, linearity correction, flat fielding, and mosaicking), as well as steps specific to the array used in MIPS (droop correction and dynamic range extension using the first difference frame) -- these steps are described in more detail in the paper. (5 data files).

  13. Draft Genome Sequence of Dematiaceous Coelomycete Pyrenochaeta sp. Strain UM 256, Isolated from Skin Scraping.

    PubMed

    Yew, Su Mei; Chan, Chai Ling; Soo-Hoo, Tuck Soon; Na, Shiang Ling; Ong, Seong Siang; Hassan, Hamimah; Ngeow, Yun Fong; Hoh, Chee Choong; Lee, Kok Wei; Yee, Wai Yan; Ng, Kee Peng

    2013-05-30

    Pyrenochaeta, classified under the order Pleosporales, is known to cause diseases in plants and humans. Here, we report a draft genome sequence of a Pyrenochaeta sp. isolated from a skin scraping, with an estimated genome size of 39.4 Mb. Genes associated with the synthesis of proteases, toxins, plant cell wall degradation, and multidrug resistance were found.

  14. A Catalog of 1.5273 um Diffuse Interstellar Bands Based on APOGEE Hot Telluric Calibrators

    NASA Astrophysics Data System (ADS)

    Elyajouri, M.; Monreal-Ibero, A.; Remy, Q.; Lallement, R.

    2016-08-01

    High resolution stellar spectroscopic surveys provide massive amounts of diffuse interstellar bands (DIBs) measurements. Data can be used to study the distribution of the DIB carriers and those environmental conditions that favor their formation. In parallel, recent studies have also proved that DIBs extracted from stellar spectra constitute new tools for building the 3D structure of the Galactic interstellar medium (ISM). The amount of details on the structure depends directly on the quantity of available lines of sight. Therefore there is a need to construct databases of high-quality DIB measurements as large as possible. We aim at providing the community with a catalog of high-quality measurements of the 1.5273 μm DIB toward a large fraction of the Apache Point Observatory Galactic Evolution Experiment (APOGEE) hot stars observed to correct for the telluric absorption and not used for ISM studies so far. This catalog would complement the extensive database recently extracted from the APOGEE observations and used for 3D ISM mapping. We devised a method to fit the stellar continuum of the hot calibration stars and extracted the DIB from the normalized spectrum. Severe selection criteria based on the absorption characteristics are applied to the results. In particular limiting constraints on the DIB widths and Doppler shifts are deduced from the H i 21 cm measurements, following a new technique of decomposition of the emission spectra. From ˜16,000 available hot telluric spectra we have extracted ˜6700 DIB measurements and their associated uncertainties. The statistical properties of the extracted absorptions are examined and our selection criteria are shown to provide a robust dataset. The resulting catalog contains the DIB total equivalent widths, central wavelengths and widths. We briefly illustrate its potential use for the stellar and interstellar communities.

  15. Experimental study of biological effect by Nd:YAP laser (1.34um)

    NASA Astrophysics Data System (ADS)

    Zhu, Jing; Zhang, Hui-Guo; Lu, Liping

    2005-07-01

    Objective: To evaluate the biological effect of different power, irradiation time of Nd: YAP laser (1341nm). Method: The canine skin, bronchia, stomach, bladder, uterus were irradiated with different irradiation power and time. The effect was observed by naked eyes, light microscope, and electric microscope. Result: Having positive correlation with power and irradiating time, the biological effect of Nd: YAP laser is mainly thermal coagulation effect with some gasified ablation effect. Under the condition where the diameter of faculae irradiating on canine skin was 3 mm, the thermal coagulation dose reaching deep derma was 5W 4s, 10w 1s;the thermal coagulation dose puncturing the whole layer was 5W, 6s, 10W, 4s; the thermal coagulation dose reaching whole stratum was 10W 5s, 20W 4s, 30W 2s, 40-60W 1s on stomach (Thickness 6mm), was 40W, 2s, 30W, 3s, 20W, 4s, 10W, 6s on bladder (Thickness 6mm ,irradiation underwater), was 10W, 4s on bronchia (Thickness 2 mm) and was 30W 3s, 20W 5s, 10W 6s on uterus (Thickness 6mm). Conclusion: Having positive correlation with power and irradiating time, the biological effect of Nd: YAP laser is mainly thermal coagulation effect with some gasified ablation effect. Under the condition where the diameter of faculae irradiating on canine skin was 3 mm, it is safe when the dose is 5W, and the irradiating time is less than 4s; the dose is 10W, and the irradiating time is less than 1 s. Under these conditions, the gastric area is used to coagulating and ablating. It is safe when the dose is less than 10W 5s, 20W 4s, 30W 2s. Under these condition, The bladder (thickness 6mm) is coagulated and ablated. It is safe when the dose is no more than 40W, 1s, 30W, 2s, 20W, 3s, 10W, 5s.Under the condition where bronchia (thickness 2mm) is coagulated and ablated, it is safe when the dose is less than 10W, 3s.Under the condition where uterus (thickness 6mm) is coagulated and ablated, it is safe when the dose is less than 30W, 2s, 20W, 4s, 10W, 5s.

  16. [Ultrasound guidance of central venous catheterisation].

    PubMed

    Le Ray Ferrières, I; Guinier, D

    2009-12-01

    Portacath implantation with introduction of a catheter into the superior vena caval system is a commonly performed procedure. Catheterization of the internal jugular vein can be difficult due to anatomical variation, individual patient morphology, or as a result of previous catheterization. Use of 2D ultrasonography facilitates localization of the internal jugular vein and decreases the risks of catheter placement.

  17. Human cerebral venous outflow pathway depends on posture and central venous pressure

    PubMed Central

    Gisolf, J; van Lieshout, J J; van Heusden, K; Pott, F; Stok, W J; Karemaker, J M

    2004-01-01

    Internal jugular veins are the major cerebral venous outflow pathway in supine humans. In upright humans the positioning of these veins above heart level causes them to collapse. An alternative cerebral outflow pathway is the vertebral venous plexus. We set out to determine the effect of posture and central venous pressure (CVP) on the distribution of cerebral outflow over the internal jugular veins and the vertebral plexus, using a mathematical model. Input to the model was a data set of beat-to-beat cerebral blood flow velocity and CVP measurements in 10 healthy subjects, during baseline rest and a Valsalva manoeuvre in the supine and standing position. The model, consisting of 2 jugular veins, each a chain of 10 units containing nonlinear resistances and capacitors, and a vertebral plexus containing a resistance, showed blood flow mainly through the internal jugular veins in the supine position, but mainly through the vertebral plexus in the upright position. A Valsalva manoeuvre while standing completely re-opened the jugular veins. Results of ultrasound imaging of the right internal jugular vein cross-sectional area at the level of the laryngeal prominence in six healthy subjects, before and during a Valsalva manoeuvre in both body positions, correlate highly with model simulation of the jugular cross-sectional area (R2 = 0.97). The results suggest that the cerebral venous flow distribution depends on posture and CVP: in supine humans the internal jugular veins are the primary pathway. The internal jugular veins are collapsed in the standing position and blood is shunted to an alternative venous pathway, but a marked increase in CVP while standing completely re-opens the jugular veins. PMID:15284348

  18. IDENTIFICATION OF CASO4 FORMED BY REACTION OF CAO AND SO2

    EPA Science Inventory

    The injection of calcium-based sorbents into coal-fired boilers for reaction with, and reduction in the levels of, sulfur dioxide (SO2) in the flue gas has undergone considerable research and development. Significant effort has also been made in developing models for the overall ...

  19. Etologia aplicada al manejo de especies amenazadas: el caso del turon de patas negras (Mustela nigripes)

    USGS Publications Warehouse

    Vargas, A.; Biggins, D.; Miller, B.

    1999-01-01

    de esta especie de un modo más eficaz y rentable. Black-footed ferrets are considered one of the world's most endangered mammals. The last wild population was discovered in 1981 in Meteetsee, Wyoming, and, in 1985 it collapsed due to an epizootic of canine distemper in combination with sylvatic plague. Prior to the extinction of the last remnant population, 18 wild black-footed ferrets were captured to initiate captive propagation efforts. Captive breeding has been successful and, during the last 11 years, more than 2600 black-footed ferrets have been born in captive breeding centers. Since 1991, approximately 870 ferrets have been reintroduced in 5 areas located within the ferret's original geographic distribution, including sites in Wyoming, Montana, South Dakota, and Arizona. Scientific research has been, and continues to be, a critical tool to direct recovery efforts. Studies in applied ethology conducted on captive and reintroduced ferret populations have demonstrated that a naturalistic captive environment, particularly during early developmental periods, enhances the expression of behaviors necessary for survival in nature. Ferrets raised in a naturalistic environment develop better predatory skills, are able to recognize prairie dog burrows as a home and shelter from predators, and are more physically fit. Results from these studies have been adapted into management strategies to help implement a more cost-effective road to black-footed ferret recovery.

  20. Materials Data on CaSO4 (SG:14) by Materials Project

    SciTech Connect

    Kristin Persson

    2014-11-02

    Computed materials data using density functional theory calculations. These calculations determine the electronic structure of bulk materials by solving approximations to the Schrodinger equation. For more information, see https://materialsproject.org/docs/calculations

  1. Materials Data on CaSO4 (SG:62) by Materials Project

    SciTech Connect

    Kristin Persson

    2014-07-09

    Computed materials data using density functional theory calculations. These calculations determine the electronic structure of bulk materials by solving approximations to the Schrodinger equation. For more information, see https://materialsproject.org/docs/calculations

  2. Cúmulos globulares en galaxias elípticas aisladas: el peculiar caso de NGC7507

    NASA Astrophysics Data System (ADS)

    Caso, J. P.; Richtler, T.; Bassino, L.

    We present results of the study of the glolular cluster system of NGC7507. The number of members of the system is calculated; and compared with other elliptical galaxies from literature. FULL TEXT IN SPANISH

  3. On telescópio remoto do Observatório Abrahão de Moraes - Obelix

    NASA Astrophysics Data System (ADS)

    Neres, N. L.; Raffaelli, J. C.; Medina Tanco, G. A.; Horvath, J. E.; Maluhy, R.; Martins, A.; Orselli, M. I. V.

    2003-08-01

    Foi desenvolvido um telescópio totalmente automático situado no Observatório Abrahão de Moraes, em Valinhos-SP, que possibilita observações remotas via Internet tanto para fins profissionais como didáticos. Usando um programa navegador da WWW, o observador tem acesso a páginas interativas que permitem não só apontar o telescópio e receber as imagens, como também controlar a abertura e o fechamento da cúpula, monitorar temperatura, umidade e orvalho e receber imagens das câmaras de segurança. O fechamento da cúpula é feito automaticamente em caso de perigo de condensação. O sistema consiste de uma câmara Apogee, uma roda de filtros SBIG modelo CFW-8 com filtros RGB e um telescópio Meade. A observação remota é feita usando programas comerciais da área. Uma caixa de controle com lógica programável controla o movimento da cúpula e a energização do telescópio. Um software em LabView adquire os dados da estação meteorológica, que inclui um sensor de chuva desenvolvido no IAG, e apresenta seus valores atuais e históricos. Usando uma facilidade do próprio LabView, a saída desse software é exportada para a Internet. Um programa em C disponibiliza as imagens das câmaras de segurança usando uma placa de captura de vídeo e um seqüencial de vídeo que foi adaptado para ser controlado pelo PC. O sistema completo já se encontra operacional.

  4. Uma comparação entre técnicas de propagação de erros em astrofísica: Monte Carlo x Bootstrap

    NASA Astrophysics Data System (ADS)

    Waelkens, A. H.; Janot Pacheco, E.

    2003-08-01

    Recentemente Dhillon & Watson (2001) criticaram o procedimento de determinação de erros via simulações de Monte Carlo no caso do imageamento indireto de estrelas, por introduzir ruído nos dados e resultar em erros superestimados. Estes autores propuseram a utilização alternativa do método de Bootstrap como uma técnica superior para a estimativa de erros. Neste trabalho apresentamos os resultados de um estudo comparativo da performance das técnicas de simulação por Monte Carlo e por Bootstrap para a determinação de erros em duas situações de interesse: (i) ajuste de modelos a espectros observados e (ii) imageamento indireto de discos de acréscimo com técnicas de mapeamento por eclipse. No caso (i), os dados de entrada são espectros de emissão simples de hidrogênio aos quais é adicionado ruído gaussiano de amplitude selecionada. No caso (ii), são produzidas curvas de luz do eclipse de uma distribuição de brilho seguindo a lei TµR-3/4 para discos estacionários cuja taxa de acréscimo varia ao longo do eclipse segundo uma distribuição gaussiana de amplitude selecionada, simulando o ruído. A avaliação da performance é feita com o auxílio de um diagrama do erro relativo na grandeza ajustada, conforme obtido por cada método, versus o erro relativo (ruído/sinal) dos dados de entrada. O estudo mostra que as duas técnicas produzem resultados semelhantes nos dois casos, e que a suposta superioridade do método de Bootstrap não se confirma.

  5. [Epidemiology of Vertigo on Hospital Emergency].

    PubMed

    Roque Reis, Luis; Lameiras, Rita; Cavilhas, Pedro; Escada, Pedro

    2016-05-01

    Introdução: A vertigem é um dos motivos mais frequentes na procura de atendimento médico especializado na urgência. O objetivo deste estudo foi avaliar o peso real que as alterações do equilíbrio têm na urgência de Otorrinolaringologia, as suas características epidemiológicas e uma eventual sazonalidade por estações do ano. Usou-se uma amostra de doentes que utilizou o serviço de urgência desta especialidade de um hospital central universitário de Lisboa durante um período de quatro anos. Material e Métodos: O projeto foi concebido como um estudo epidemiológico descritivo de tipo populacional, retrospectivo, no período de 2010 a 2013. Incluiu uma população total de 40 173 atendimentos de doentes que nesse período utilizou o serviço de urgência de Otorrinolaringologia. As variáveis estudadas incluíram a idade, género, número anual de casos (total e percentual), data da crise de vertigem, distribuição sazonal por estações do ano e proporção anual de casos internados. Resultados: Um total de 4 347 doentes (10,8%) procurou atendimento médico devido a vertigem ou alterações do equilíbrio ao longo dos quatro anos do estudo. Verificou-se um aumento anual do número de casos entre 7,6% (em 2010) a 17% (em 2013). As mulheres foram mais frequentemente afetadas (68,3%) e as crises ocorreram mais frequentemente em indivíduos entre os 60 e 79 anos de idade (40%). Os casos distribuíram-se de forma heterogénea entre as estações do ano, havendo mais episódios de vertigem no verão e no outono e com uma tendência crescente entre 2010 e 2013. O número de internamentos aumentou anualmente nesse período. Discussão: A epidemiologia da vertigem e dos distúrbios vestibulares específicos é ainda um campo a estudar, pois pode ter utilidade para a tomada de decisões clínicas e para o planeamento dos cuidados de saúde. Conclusão: O estudo revelou que os casos de vertigem na urgência aumentaram anualmente e são mais frequentes no sexo

  6. Foreign body ingestion: rare cause of cervical abscess.

    PubMed

    Costa, Liliana; Larangeiro, João; Pinto Moura, Carla; Santos, Margarida

    2014-01-01

    IntroduçÉo: A ingestÉo de corpo estranho é um motivo frequente de recurso à urgência hospitalar. As complicações graves, embora raras, incluem perfuraçÉo faringo-esofágica, fistula aorto-esofágica e infecçÉo cervical profunda.Material e Métodos: Foram analisados, retrospectivamente, os casos de ingestÉo de corpo estranho com internamento num hospital terciário, entre 1989 e 2011. Seleccionaram-se os casos complicados por abcesso cervical profundo, descrevendo-se a semiótica, resultados de meios complementares de diagnóstico, terapêutica efectuada e evoluçÉo clínica.Resultados: Dos 1679 casos, 319 referentes a crianças e 1360 a adultos, reportam-se dois casos (0,12%): uma criança, 13 meses, com abcesso retrofaríngeo após ingestÉo de osso de frango e um adulto, 41 anos, com abcesso parafaríngeo após ingestÉo de espinha de peixe. As complicações manifestaram-se quatro e três dias após remoçÉo do corpo estranho, respectivamente. Em ambos foram efectuadas Tomografias Computorizadas cervicais com contraste e drenagem cirúrgica dos abcessos; a criança foi ainda submetida a esofagoscopia rígida para remoçÉo de corpo estranho residual e encerramento da perfuraçÉo esofágica associada.DiscussÉo: Os abcessos cervicais sÉo uma complicaçÉo possível da ingestÉo de corpo estranho e constituem um desafio diagnóstico, principalmente em idade pediátrica. A manipulaçÉo esofágica prévia por fibroscopia poderá ser considerada um factor de risco. A imagiologia (Tomografia Computorizada cervical com contraste ou Resson'ncia Magnética Cervical) foi essencial para o diagnóstico e o planeamento cirúrgico.ConclusÉo: Embora raros, perante a história recente de ingestÉo/remoçÉo de corpo estranho esofágico e a presença de sintomas compatíveis, os abcessos cervicais devem ser tidos em consideraçÉo, dado o potencial de morbilidade e mortalidade na ausência de uma abordagem terapêutica adequada.

  7. [Prevalence of chromosomal abnormalities in spontaneous abortions or fetal deaths].

    PubMed

    Bastos, Raquel; Ramalho, Carla; Dória, Sofia

    2014-01-01

    Introdução: O abortamento espontâneo é um dos problemas mais frequentes da gravidez, estimando-se que afete, pelo menos, 25% das mulheres que tentam engravidar. O objetivo principal deste trabalho foi o estudo da prevalência das anomalias cromossómicas em perdas gestacionais, analisando a sua relação com a idade materna, idade gestacional e história de abortamentos prévios.Material e Métodos: Realizou-se um estudo retrospetivo em 401 casos de perdas de gravidez que efetuaram análise citogenética e anátomo-patológica, entre janeiro de 2008 e junho de 2012, no Centro Hospitalar de S. João.Resultados: Dos 401 casos enviados para estudo citogenético foi possível obter informação sobre o complemento cromossómico em 333 casos, dos quais 72,7% apresentaram cariótipo normal e 27,3% cariótipo anormal. As aneuploidias representaram 92,3% das cromossomopatias identificadas, sendo as trissomias as mais frequentes, associadas a uma idade materna avançada e a uma idade gestacional precoce. Não se verificou concordância entre os resultados da análise anátomo-patológica e citogenética.Discussão e Conclusão: A prevalência de anomalias cromossómicas, no primeiro trimestre, foi semelhante entre os casos de abortamento esporádico e recorrente. Com o aumento da idade materna observou-se um aumento das trissomias, com um incremento médio de 7,4% no risco de ocorrência por ano. Não foi estabelecida uma correlação cariótipo-patológica significativa. A contaminação materna da amostra foi o principal entrave à determinação exata da prevalência de anomalias cromossómicas. As técnicas de citogenética molecular já disponíveis podem colmatar esta e outras limitações da técnica convencional.

  8. Late stillbirth: a ten year cohort study.

    PubMed

    Robalo, Raquel; Pedroso, Célia; Amaral, Njila; Soares, Clara

    2013-01-01

    Introdução: A morte fetal tardia é um acontecimento que se mantém na prática diária, apesar de protocolos de vigilância pré-natal e intraparto. Objectivo: Análise dos factores que contribuíram para a causa principal ou condições associadas a morte fetal tardia num período de 10 anos Métodos: Coorte retrospectiva de 208 gestações tardias simples, cujo parto em unidade terciária de cuidados perinatais resultou no nascimento de um nado morto, num período de dez anos. Através de consulta de processo clínico foram analisados dados clínicos, laboratoriais e resultados de estudo anatomo-patológico feto-placentário. Resultados: A incidência de morte fetal tardia foi de 3,5 por cada 1000 nascimentos. Não foram encontradas quaisquer tendências na incidência de MF tardia ao longo do tempo de estudo. Em 12 (5,8%) casos a morte fetal foi um acontecimento intraparto e 72 (35%) eram gestações de termo. Em 14% a gravidez não foi vigiada. A IG média de diagnóstico foi 34 semanas. A principal causa de morte associou-se a patologia fetal, tendo sido identificados factores fetais em 59 casos, destes 25% foram considerados leves para a idade gestacional. Em 24.5% dos casos a causa de morte foi inexplicada. Identificaram-se factores de risco materno em 21% dos casos, a patologia hipertensiva foi frequente e foi associada a idade gestacional precoce (p = 0,028). Conclusões: Não houve oscilações na incidência de morte fetal tardia ao longo dos dez anos avaliados. A incidência foi de 3,5‰, idêntica à descrita em países desenvolvidos. Cerca de um quarto das mortes fetais foram inexplicadas. A patologia materna mais frequente foi a hipertensão crónica.

  9. Omental infarction: a reappraisal of conservative management in children.

    PubMed

    Estevão-Costa, José; Alvarenga, Ana Sofia; Fragoso, Ana Catarina; Garcia, Maria; Campos, Miguel

    2014-01-01

    Introdução: A melhoria da acuidade diagnóstica do enfarte do omento resultou num incremento da atitude conservadora no seu tratamento. Com o objectivo de avaliar a eficácia e segurança da abordagem não-operatória, analisámos os casos de enfarte do omento tratados num hospital terciário. Material e Métodos: Incluímos os casos de enfarte do omento primários tratados entre 2004 e 2011. Os enfartes do omento diagnosticados por imagiologia foram submetidos a tratamento conservador que constou de analgésicos e antibioterapia intravenosa. Avaliámos os dados demográficos, apresentação clínica, dados laboratoriais, imagiologia e resultado. Resultados: Ocorreram nove casos de enfarte do omento. Oito pacientes (4 rapazes), com uma idade mediana de 8,5 anos, apresentaram- se na fase inicial da doença por dor abdominal à direita; a contagem leucocitária era normal ou ligeiramente elevada. Seis casos, diagnosticados por TC após ecografia suspeita de enfarte do omento em quatro, foram trados conservadoramente sem complicações, tendo alta ao terceiro dia (mediana). Dois doentes foram apenas diagnosticados durante a intervenção cirúrgica por suposta apendicite. O nono caso apresentou-se com uma obstrução intestinal devida a hérnia interna que foi resolvida por laparoscopia. Discussão: A imagiologia foi diagnóstica na maioria dos casos de enfarte do omento, permitindo a adoção de uma abordagem conservadora. O tratamento não-operatório foi eficaz e sem complicações em todos os doentes que se apresentaram na fase inicial da doença. Um doente apresentou-se com uma complicação grave que requereu intervenção cirúrgica. Conclusão: Na ausência de um tratamento consensual para o enfarte do omento, a abordagem não-operatória é uma alternativa não invasiva e eficaz, mas requer uma vigilância clínica ativa.

  10. A teoria da percolação aplicada às galáxias aneladas peculiares

    NASA Astrophysics Data System (ADS)

    Poppe, P. C. R.; Martin, V. A. F.; de Medeiros, N. G. F.; Faúndez-Abans, M.; Oliveira-Abans, M.

    2003-08-01

    Formulado no final da década de 50, o modelo de percolação concentra-se em descrever o meio poroso, que será visto neste trabalho como uma rede de canais aleatórios, por onde escoa um fluido determinístico. Se o número de canais for suficientemente grande, então eles estarão ligados e o meio se tornará permeável à passagem do fluido. Neste caso, dizemos que houve a percolação do fluido. Reformulando o modelo acima, podemos escrever um código particularmente adaptado para simulações em Galáxias, onde iremos supor que os canais formam um reticulado, e que cada sítio da rede representa um poro que será interpretado como uma região ativa de formação estelar. Para cada elo teremos um pequeno canal ligando dois sítios vizinhos, que poderá, após um tempo "t", induzir ou não a formação de uma região ativa no poro vizinho. Para simular a passagem desta região ativa através dos poros, diremos que um elo está aberto com probabilidade p e fechado com probabilidade 1-p. Dessa forma, passamos a imaginar configurações de elos abertos e fechados, onde cada configuração ocorre com uma certa probabilidade, dada por p|A|(1-p)|F|, onde |A| é o número de elos abertos e |F| o número de elos fechados da configuração. A expressão anterior só tem importância física se |A| e |F| forem ambos finitos, pois, caso contrário, a probabilidade de ocorrência de uma dada configuração será sempre nula. Neste trabalho, foram considerados dados cinemáticos publicados na literatura bem como aqueles obtidos pelos autores a partir de observações fotométricas realizadas no Observatório de Las Campanãs, em 1994, para a Galáxia Anelada Peculiar HRG 03401. Mostraremos que para certos valores de p, situados entre 0,5 e 0,6, os clusters assim formados irão simular, de maneira coerente, o referido objeto.

  11. Detection and Intervention Strategies by Primary Health Care Professionals in Suspected Elder Abuse.

    PubMed

    Ferreira, Mafalda; dos Santos, César Lares; Vieira, Duarte Nuno

    2015-01-01

    Introdução: Os profissionais dos cuidados de saúde primários encontram-se numa posição privilegiada para identificarem e orientarem casos de maus-tratos de idosos. Este estudo investigou o enquadramento destes profissionais nesta matéria. Material e Métodos: Elaborou-se um questionário posteriormente aplicado a Médicos e enfermeiros de 12 Unidades de Saúde de Coimbra. Estudaram-se par'metros relacionados com aspetos demográficos, perceção do abuso e estratégias de atuação, experiência pessoal e formação nesta área. Resultados: A taxa global de resposta foi de 67,9% com 127 questionários validados. Dos resultados obtidos destacam-se seguintes: verificou-se um contacto substancial entre os profissionais e a população idosa; a maioria dos profissionais (64,6%) consideram o abuso mais prevalente em contexto familiar e 32,3% indicaram a negligência como a forma mais frequente; 97,6% dos profissionais considera que tem um papel importante na deteção de casos de abuso; a incerteza no diagnóstico foi um dos principais fatores limitadores da denúncia; verificou-se incerteza a obrigatoriedade de reportar os casos às autoridades judiciais. Ainda se constatou que 87,4% destes profissionais se sentiriam mais confortáveis com protocolos de atuação e que esta problemática não havia sido abordada na sua formação básica em 70,9% dos casos. Discussão: O contato significativo entre a população idosa e os profissionais de saúde propicia o diagnóstico e intervenção precoces. Os profissionais revelaram conhecimentos sobre o tema em linha com os indicados por alguns estudos, nomeadamente, sobre o contexto e prevalência do abuso. A subsistência de dúvidas relativamente à melhor forma para gerir estes casos e conciliar as diferentes perspetivas poderia ser colmatado, na opinião veiculada pelos próprios, pela definição de protocolos de atuação e a formação específica deverá ser considerada como um dos pilares fundamentais para

  12. Two cases of the same family with the unusual elevation of CA19-9 levels.

    PubMed

    Uyanik, Metin; Sertoglu, Erdim; Serdar, Muhittin A; Aydin, Fevzi N; Ozgurtas, Taner; Kurt, Ismail

    2014-01-01

    Introdução: O antigénio carbohidrato (CA19-9) presente no soro é um marcador amplamente utilizado na prática clínica e apresenta pequenos aumentos em algumas doenças benignas. Aqui relatamos dois casos saudáveis, uma mãe e a sua filha, com níveis CA19-9 um pouco elevados.Casos Clínicos: A mãe, com um nível CA19-9 elevado (89,90 U/mL; limite superior do intervalo normal (ULNR) < 37 U/mL) foi encaminhada ao nosso departamento para avaliação. Um aumento semelhante foi incidentalmente determinado na sua filha. O nível de CA19-9 da filha era 123,92 U/mL. Os restantes parametros laboratoriais avaliados, estudos imagiológicos e avaliações clínicas revelaram-se dentro dos limites da normalidade. Não foi encontrada, qualquer patologia que justifique elevado nível de CA19-9. A fim de evitar erros de laboratório ou possíveis interferências, as amostras foram analisadas em quatro plataformas de imunoensaios diferentes, em duplicado.Conclusão: As pessoas saudáveis podem ter níveis da CA19-9 superiores aos limites de referência. Portanto, os médicos precisam estar cientes dessas situações raras, sem falhar o diagnóstico de doenças malignas.

  13. The Role of the Paratrigeminal Nucleus in Vagal Afferent Evoked Respiratory Reflexes: A Neuroanatomical and Functional Study in Guinea Pigs

    PubMed Central

    Driessen, Alexandria K.; Farrell, Michael J.; Mazzone, Stuart B.; McGovern, Alice E.

    2015-01-01

    The respiratory tree receives sensory innervation from the jugular and nodose vagal sensory ganglia. Neurons of these ganglia are derived from embryologically distinct origins and as such demonstrate differing molecular, neurochemical and physiological phenotypes. Furthermore, whereas nodose afferent neurons project to the nucleus of the solitary tract (nTS), recent neuroanatomical studies in rats suggest that jugular neurons have their central terminations in the paratrigeminal nucleus (Pa5). In the present study we confirm that guinea pigs demonstrate a comparable distinction between the brainstem terminations of nodose and jugular ganglia afferents. Thus, microinjection of fluorescently conjugated cholera toxin B (CT-B) neural tracers into the caudal nTS and Pa5 resulted in highly specific retrograde labeling of neurons in the nodose and jugular ganglia, respectively. Whereas, nodose neurons more often expressed 160 KD neurofilament proteins and the alpha3 subunit of Na+/K+ ATPase, significantly more jugular neurons expressed the neuropeptides substance P (SP) and, especially, Calcitonin Gene-Related Peptide (CGRP). Indeed, terminal fibers in the Pa5 compared to the nTS were characterized by their significantly greater expression of CGRP, further supporting the notion that jugular afferents project to trigeminal-related brainstem regions. Electrical stimulation of the guinea pig larynx following selective surgical denervation of the nodose afferent innervation to the larynx (leaving intact the jugular innervation) resulted in stimulus dependent respiratory slowing and eventual apnea. This jugular ganglia neuron mediated response was unaffected by bilateral microinjections of the GABAA agonist muscimol into the nTS, but was abolished by muscimol injected into the Pa5. Taken together these data confirm that jugular and nodose vagal ganglia afferent neurons innervate distinct central circuits and support the notion that multiple peripheral and central pathways

  14. GTE_TRACEP_P3B Parameters 8

    Atmospheric Science Data Center

    2013-02-19

    ... (-90, 90)(-180,180) Parameters:  FSSP integral number 0.3 um <= Dp <= 1.0 um 1.0 um <= Dp <= 20.0 um 0.3 um <= Dp <= 20.0 um FSSP integral surface area 0.3 um <= Dp <= 1.0 um 1.0 um <= Dp <= 20.0 um ...

  15. [Rare anatomical variation of absence of the sciatic nerve: completely substituted by the tibial and common fibular nerve].

    PubMed

    Coelho, Paulo; Melo, Catarina; Bernardes, António

    2013-01-01

    Introdução: Existem várias publicações referindo variantes anatómicas do nervo ciático, algumas associadas a síndromes clínicos (como sendo a síndrome do músculo piriforme). Neste contexto, pretendemos apresentar uma variante anatómica rara do nervo ciático.Casos clínicos: Dois cadáveres leucodérmicos, masculinos, com 74 e 78 anos, falecidos de morte natural, sem patologia do membro inferior. Em ambos os casos, observou-se ausência do nervo ciático direito, tendo os nervos tibial e fibular comum origem e trajecto independentes, desde a sua origem nas raízes lombo-sagradas até à região poplítea. O nervo ciático contralateral apresentava a anatomia habitual.Discussão: Analisando a literatura, na Medline, realçamos que apresentamos dois casos raros de ausência do nervo ciático, com origem e trajecto independentes dos nervos tibial e fibular comum. Esta variante poderá ter implicações clínicas, nomeadamente ser um factor de risco para o insucesso de bloqueios anestésicos poplíteos e para a síndrome do músculo piriforme.

  16. [Auditory Neuropathy: Clinical Evaluation and Diagnostic Approach].

    PubMed

    Carvalho, Guilherme Machado; Leão, Beatriz Prista; Ramos, Priscila Zonzini; Guimarães, Alexandre Caixeta; Castilho, Arthur Menino; Sartorato, Edi Lúcia

    2016-06-01

    Introdução: A neuropatia auditiva é uma condição na qual há alteração na condução neuronal do estímulo sonoro. Este trabalho pretende descrever e caracterizar a casuística de doentes com neuropatia auditiva. Material e Métodos: Realizámos um estudo transversal, retrospetivo, com descrição de uma série de casos consecutivos. O diagnóstico da neuropatia auditiva foi definido nas seguintes situações: Presença de otoemissões acústicas com potenciais auditivos de tronco encefálico ausente ou anormal e presença do microfonismo coclear independentemente da presença de otoemissões acústicas. Resultados: Foram avaliados 34 doentes com perda auditiva bilateral, 67% deles do sexo masculino. O aparecimento dos sintomas foi congênito em 80% dos casos. Na pesquisa das otoemissões acústicas, a resposta foi ausente em 67% dos doentes. O microfonismo coclear foi detetado em 79% dos doentes. Antecedentes gestacionais, perinatais ou ambientais relevantes estiveram presentes em 35,3% dos casos. Discussão: A literatura médica ainda apresenta grande variabilidade nos achados relacionados com a neuropatia auditiva, tanto na sua etiologia quanto nos dados epidemiológicos. Conclusão: A neuropatia auditiva apresenta um amplo espectro de alterações que podem resultar em disfunções leves a severas no funcionamento da via auditiva. Na nossa amostra, observámos que 80% das neuropatias auditivas terão tido origem congênita e/ou apresenta microfonismo coclear, 91% dos doentes apresenta défice auditivo significativo e 53% sofrem de surdez severa ou profunda.

  17. [Bronchopleurocutaneous Fistula: A Rare Complication of Pulmonary Tuberculosis].

    PubMed

    Montez, Ana Sofia José; Coutinho, Daniel; Velez, Jorge; Freitas, Filomena; Oliveira, Célia

    2015-01-01

    Introdução: A tuberculose pulmonar pode cursar com diversas complicações. As fístulas bronco-pleuro-cutâneas consistem em comunicações anormais entre o brônquio, o espaço pleural e a pele.Caso Clínico: Apresentamos o caso de um homem, 47 anos, esquizofrénico, enviado ao Serviço de Urgência por toracalgia esquerda, tosse produtiva e emagrecimento. Apresentava-se caquético, sendo evidente um orifício cutâneo torácico latero-anterior esquerdo com drenagem purulenta, na qual o exame direto revelou bacilos ácido-álcool resistentes. A radiografia torácica evidenciava infiltrado heterogéneo bilateral. Foi internado com o diagnóstico de tuberculose pulmonar fistulizada. Na expetoração, a pesquisa de bacilos ácido-álcool resistentes foi igualmente positiva, sendo evidenciado Mycobacterium tuberculosis por reação de polimerase em cadeia e exame cultural. Iniciou terapêutica antituberculosa quádrupla apresentando evolução clínica favorável.Conclusões: A formação de fístulas bronco-pleuro-cutâneas é atualmente e em países desenvolvidos, uma complicação rara de tuberculose pulmonar. Assim, apesar da tuberculose ser frequente em Portugal, a raridade deste tipo de complicações torna pertinente a apresentação deste caso clínico.

  18. Simulação de ejeções de massa coronal

    NASA Astrophysics Data System (ADS)

    Corsini, M. A.; Silva, A. V. R.

    2003-08-01

    Ejeções de massa coronal (EMC) são bolhas gigantes de gás permeadas por campos magnéticos que são ejetadas do Sol durante um período de várias horas. Caso estas ejeções atinjam a Terra, geralmente, causam uma série de distúrbios às comunicações de longa distância e navegação, além de danos a satélites e transformadores. Portanto, é desejável que sejamos capazes de prever quando estas ejeções atingirão a Terra. Para tanto, é necessário um bom entendimento dos mecanismos causadores das ejeções e, principalmente, de como se dá a propagação das EMC e sua interação com o vento solar que permeia o meio interplanetário. Nesse sentido foi desenvolvido um programa computacional para resolver as equações MHD (Magneto-Hidro-Dinâmica) que regem a evolução das EMC. Primeiramente foram estabelecidas as condições necessárias para descrever o vento solar, no estado estacionário, que permeia todo o meio interplanetário. Num primeiro momento, resolveu-se o sistema de equações para o caso do vento isotérmico, conhecida como a solução de Parker, a fim de testarmos o modelo. Então, foi considerado o caso do vento solar com temperatura variável no meio interplanetário. Este resultado foi utilizado como a base de nosso sistema em seu instante inicial. Posteriormente foram feitas as considerações necessárias para descrever a propagação da Ejeção de Massa Coronal. As EMC foram simuladas como um aumento de densidade e temperatura local na coroa solar. A órbita e a posição da Terra foram incluídas no sistema. Os dados gerados possibilitaram uma análise da evolução da EMC pelo meio interplanetário até encontrar-se com a Terra. Os perfis de densidade e temperatura a 1 Unidade Astronômica são comparados com os dados de satélites reportados na literatura.

  19. Anatomical basis of central venous catheter fracture.

    PubMed

    Jensen, Mark O

    2008-03-01

    Central venous catheter fracture is a rare complication of long-term indwelling subclavian venous access. Subclavian vein access has been the recommended approach for placing central venous catheters. The anatomical landmark method for subclavian access remains a highly successful and nonequipment-dependent method for rapid central access. More recently, the internal jugular vein approach has emerged as the preferred route for long-term central venous access. However, variations in internal jugular vein anatomy make the landmark method less reliable. Use of two-dimensional real-time ultrasound during internal jugular vein access is associated with better success, a lower complication rate, and faster access. A case of central venous catheter fracture initiated an internal review of long-term central venous access procedures. We have converted to a predominantly internal jugular vein approach. This case report and literature review may assist other physicians and institutions in re-evaluating long-term central venous access protocols.

  20. Unilateral vocal cord palsy and dysphagia: an unusual presentation of cerebellopontine angle meningioma

    PubMed Central

    Senior, Andrew; Douglas, James Andrew; Thompson, Stuart

    2015-01-01

    Cerebellopontine angle (CPA) tumours are the most common neoplasms in the posterior fossa, accounting for 5–10% of intracranial tumours. Most CPA tumours are benign, with most being vestibular schwannomas. Meningiomas arising from the jugular foramen are among the rarest of all with very few being described in the literature. Treatment options vary considerably as experience with these tumours is limited. One option is a skull base approach, but this depends on size, location and ability to preserve lower cranial nerve function. This can be extremely challenging and is accompanied by high mortality risk; therefore, a more conservative option must be considered. This case report highlights the difficulty in management of patients with jugular fossa meningiomas, including appropriate investigations, analysis of surgical versus conservative treatment and associated complications. Furthermore, we elaborate the decision-making process pertaining to the tailoring of the surgical route used for the resection of jugular foramen meningiomas. (Jugular Foramen Meningioma, cerebellopontine angle). PMID:26486157

  1. Central venous catheter placement: where is the tip?

    PubMed

    Ibrahim, George M

    2012-09-01

    The insertion of central venous catheters is a common bedside procedure performed in intensive care units. Here, we present a case of an 82-year-old man who underwent insertion of a central venous catheter in the internal jugular vein without perceived complications. Postprocedural radiographs showed rostral migration of the catheter, and computed tomography performed coincidentally showed cannulation of the jugular bulb at the level of the jugular foramen. To our knowledge, this is the first report to document migration of a central venous catheter from the internal jugular vein into the dural sinuses, as confirmed by computed tomography. The case highlights the importance of acquiring postprocedural radiographs for all insertions of central venous catheters to confirm catheter placement.

  2. Identification of the Mechanisms Underlying Antiestrogen Resistance: Breast Cancer Research Partnership between FIU-UM Braman Family Breast Cancer Institute

    DTIC Science & Technology

    2009-06-01

    level of p27 i n LY2 (Tamoxifen resistant) breast cancer cells exposed to antiestrogens. As shown in Fig. , tamoxifen e xposed LY2 cells...ove rall h ypothesis b ecause i t s hows t hat p27 l evels a re r estored w hen e xposed t o t amoxifen. T hus, t he Results: 6 increase in p27...degradation of p27. This increases t he l evels o f p27 in L Y2 cells e xposed t o tamoxifen which in turn inhibits cell cycle progression. These da ta p

  3. Wartime Requirements for Ammunition, Materiel and Personnel (WARRAMP). Volume III. Ammunition Post Processor User’s Manual (APP-UM).

    DTIC Science & Technology

    1981-12-01

    147.21 1070.18 2280.10? HELO CREW 41.35 NONCRM 609.6? 1362.92 16.70 47.00 1051.03 203.22 6720.51 ARTILLERY .00 .00 .00 .00 .00 .00 .00 : LS . 19.51...I *,/kU 19 - USL m.C),F I UEtq I L -J IAPPH 1 .41/ 21 MkT LU I.,L:NTLALobaLJJGLii/ / .. tsd) 22 kWALU LO,,FIULNr1AL*37A.I,10F./ / 2.3 613RPT PK 4Ti 24...resolution model that simulates tactical combat between a r , v: d blue force; a production model that produces force on 7.1r--# - Ls . ELCON Equipment

  4. Identification of the Mechanisms Underlying Antiestrogen Resistance: Breast Cancer Research Partnership between FIU-UM Braman Family Breast Cancer Institute

    DTIC Science & Technology

    2008-06-01

    Antiestrogen resistant cell lines LCC-2 and LY-2 regained sensitivity to the growth inhibitory effects of antiestrogens Tamoxifen and Fulvestrant by...estrogen therapy . This research is of significant merit because of its clinical relevance to breast cancer. Secondly, the research accomplishments...breast tumor resistance to anti-estrogen therapy . We proposed to investigate how reactive oxygen species (ROS)-induced redox signaling pathways in breast

  5. Identification of the Mechanisms Underlying Antiestrogen Resistance: Breast Cancer Research Partnership between FIU-UM Braman Family Breast Cancer Institute

    DTIC Science & Technology

    2012-06-01

    proliferation in breast cancer cells upon treatment with antiestrogen Tamoxifen, and the cotreatment with ebselen or overexpression of catalase may restore...compounds to produce ROS were inhibited by overexpression of catalase (CAT) or manganese superoxide dismutase (MnSOD) or treatment with Ebselen (Fig...tumors in soft agar in the presence of tamoxifen, we would expect that the overexpression of ROS modifier TrxR2, catalase or MnSOD, or antioxidant

  6. Identification of the Mechanisms Underlying Antiestrogen Resistance: Breast Cancer Research Partnership Between FIU-UM Braman Family Breast Cancer Institute

    DTIC Science & Technology

    2011-06-01

    to breast cancer cells. The abilities of these compounds to produce ROS were inhibited by overexpression of catalase (CAT) or manganese superoxide...modifier TrxR2, catalase or MnSOD, or antioxidant treatment would cause tamoxifen to regain its growth inhibitory effects in this antiestrogen...effect of ROS modifiers catalase and MnSOD had on the protein level of p27 in LCC2 (Tamoxifen resistant) breast cancer cells exposed to

  7. Espectroscopia infravermelha para a determinacao de carbono do solo: Perspectiva de um metodo economicamente viavel e ambientalmente seguro

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The Kyoto Protocol is an agreement among many of the world’s nations to, among other things, reduce atmospheric carbon dioxide concentrations in order to reduce global warming. One potential method to do so is to sequester carbon in soils. This has had the effect of stimulating the establishment of ...

  8. IN Like Flint: How the Innovation Incubator at UM-Flint Fosters Social Entrepreneurship in a City Remaking Itself

    ERIC Educational Resources Information Center

    Custer, Nic

    2015-01-01

    This paper focuses on how the University of Michigan-Flint's Innovation Incubator supports emerging for-profit businesses and nonprofit organizations through programming, business plan development, and ongoing mentorship. The Incubator is especially interested in supporting start-ups that address key social issues in the surrounding community,…

  9. Pulsed-laser-induced damage in semiconductors Ge, ZnS, and ZnSe at 10.6um

    NASA Astrophysics Data System (ADS)

    Lefranc, Sebastian; Kudriavtsev, Eugene M.; Autric, Michel L.

    1998-04-01

    Laser irradiation induced damage to several materials of interest for use as 10.6 micrometers laser system windows is investigated in this paper. The irradiation source in these single shot experiments was a pulsed TEA CO2 laser. Damage initiation in semiconductors has been studied during the interaction by measuring the variation of the transmitted intensity of a He- Ne and a CO2 cw lasers through the samples. Results show that damages appear at the beginning of the laser-matter interaction process on both surfaces and in the bulk of the materials. The damaged materials have been characterized for various incident fluences by means of optical microscopy and scanning electron microscopy in terms of topography and morphology. The modified surface chemical analysis and the structural analysis have been carried out using energy dispersive x-ray and Raman spectroscopy.

  10. Spectral Irradiance Calibration in the Infrared. 4; 1.2-35um Spectra of Six Standard Stars

    NASA Technical Reports Server (NTRS)

    Cohen, Martin; Witteborn, Fred C.; Walker, Russell G.; Bregman, Jesse D.; Wooden, Diane H.

    1995-01-01

    We present five new absolutely calibrated continuous stellar spectra from 1.2 to 35 microns, constructed as far as possible from actual observed spectral fragments taken from the ground, the Kuiper Airborne Observatory (KAO), and the IRAS Low Resolution Spectrometer (LRS). These stars, Beta Peg, Delta Boo, Beta And, Beta Gem, and Delta Hya, augment our already created complete absolutely calibrated spectrum for a Tau. All these spectra have a common calibration pedigree. The wavelength coverage is ideal for calibration of many existing and proposed ground-based, airborne, and satellite sensors.

  11. Room temperature continuous wave InGaAsN quantum well vertical cavity lasers emitting at 1.3 um

    SciTech Connect

    CHOQUETTE,KENT D.; KLEM,JOHN F.; FISCHER,ARTHUR J.; SPAHN,OLGA B.; ALLERMAN,ANDREW A.; FRITZ,IAN J.; KURTZ,STEVEN R.; BREILAND,WILLIAM G.; SIEG,ROBERT M.; GEIB,KENT M.; SCOTT,J.W.; NAONE,R.L.

    2000-06-05

    Selectively oxidized vertical cavity lasers emitting at 1294 nm using InGaAsN quantum wells are reported for the first time which operate continuous wave at and above room temperature. The lasers employ two n-type Al{sub 0.94}Ga{sub 0.06}As/GaAs distributed Bragg reflectors each with a selectively oxidized current aperture adjacent to the optical cavity, and the top output mirror contains a tunnel junction to inject holes into the active region. Continuous wave single mode lasing is observed up to 55 C. These lasers exhibit the longest wavelength reported to date for vertical cavity surface emitting lasers grown on GaAs substrates.

  12. VizieR Online Data Catalog: 24um fluxes of GOODS-S AGN (Garcia-Gonzalez+, 2015)

    NASA Astrophysics Data System (ADS)

    Garcia-Gonzalez, J.; Alonso-Herrero, A.; Perez-Gonzalez, P. G.; Hernan-Caballero, A.; Sarajedini, V. L.; Villar, V.

    2015-06-01

    We compiled all the data taken around the GOODS South field with the MIPS instrument at 24μm by querying the Spitzer Heritage Archive.1 This field was observed by Spitzer during several campaigns from 2004 January to 2007 March. We focused our study on a region around RA=03:32:36 (J2000) and DE=-27:48:39 (J2000). These data correspond to different observing proposals from different PI, including the Guaranteed Time Observations programme (GTO, PI: G. Rieke) and the GOODS programme (PI: M. Dickinson). We have obtained 151 AORs (Astronomical Observation Request) but only downloaded 127 because the others were from the SWIRE (Spitzer Wide-area InfraRed Extragalactic) survey and were not sufficiently deep. (2 data files).

  13. The relationship between English language learning strategies and proficiency of pre-university students: A study case of UMS

    NASA Astrophysics Data System (ADS)

    Kiram, Johannah Jamalul; Sulaiman, Jumat; Swanto, Suyansah; Din, Wardatul Akmam

    2014-07-01

    This paper seeks to investigate the relationship between language learning strategies and proficiency in English. Fifty-six pre-university students (22 males, 34 females) of University Malaysia Sabah participated in this study. Oxford's Strategy Inventory for Language Learning (SILL) self-report questionnaire was adopted to identify the students' language learning strategies, whereas their proficiencies were judged based on their Malaysian University English Test (MUET) Results. Pearson's correlation coefficient, Spearman's rank correlation coefficient and the t-test were utilized to make statistical interpretation about the relationship. The knowledge obtained from this study will be helpful for future studies on how to improve the quality of learning and proficiency in English.

  14. Modeling the language learning strategies and English language proficiency of pre-university students in UMS: A case study

    NASA Astrophysics Data System (ADS)

    Kiram, J. J.; Sulaiman, J.; Swanto, S.; Din, W. A.

    2015-10-01

    This study aims to construct a mathematical model of the relationship between a student's Language Learning Strategy usage and English Language proficiency. Fifty-six pre-university students of University Malaysia Sabah participated in this study. A self-report questionnaire called the Strategy Inventory for Language Learning was administered to them to measure their language learning strategy preferences before they sat for the Malaysian University English Test (MUET), the results of which were utilised to measure their English language proficiency. We attempted the model assessment specific to Multiple Linear Regression Analysis subject to variable selection using Stepwise regression. We conducted various assessments to the model obtained, including the Global F-test, Root Mean Square Error and R-squared. The model obtained suggests that not all language learning strategies should be included in the model in an attempt to predict Language Proficiency.

  15. The Navy of Brazil: An Emerging Power at Sea (Marinha do Brasil: Um Poder Emergente no Mar),

    DTIC Science & Technology

    1983-01-01

    neighboring countries were solved through diplomacy. Second, the Brazilian economy remained essentially based on agricultural production, with little...emphasis on the industrialization process that took place in other parts of the world. As a result, the technological base gained by the war effort...industrial base , many problems were not solved and dependence on foreign support was almost absolute. These facts became more evident when Brazil, after having

  16. CONTINUOUS MEASUREMENT OF PARTICLES (0.01-20.0 UM) IN AN OCCUPIED HOME, REED AND WALLACE, AAAR.

    EPA Science Inventory

    To better understand the contribution of outdoor and indoor sources to particle concentrations found in residential indoor air, an extensive monitoring effort has been undertaken in a three-story townhouse located in Reston, VA. Of particular interest was the determination of i...

  17. "Disability Means, um, Dysfunctioning People": A Qualitative Analysis of the Meaning and Experience of Disability among Adults with Intellectual Disabilities

    ERIC Educational Resources Information Center

    Monteleone, Rebecca; Forrester-Jones, Rachel

    2017-01-01

    Background: There has been little qualitative analysis of the experience of stigma, social comparisons and conception of identity among adults with intellectual disabilities (ID). This study aimed to develop an understanding of how adults with intellectual disabilities experience their own disability, and any implications relating to self-esteem,…

  18. Cozinha: Um Lugar para a "bildung" dos Educadores (The Kitchen: A Place for the "bildung" of Educators).

    ERIC Educational Resources Information Center

    Damiano, Gilberto

    2000-01-01

    Uses a kitchen metaphor for philosophy of education, in dialogue with Augustine, Erasmus of Rotterdam, Brillat-Savarin, and others. Mixes and cooks ingredients in thinking: the centrality of the human being, corporeality, historicity, and transcendency; food as sign-symbol; eating-linguistic habits; educator-cook; space of the kitchen; sensuality,…

  19. Spectrally Consistent Scattering, Absorption, and Polarization Properties of Atmospheric Ice Crystals at Wavelengths from 0.2 to 100 um

    NASA Technical Reports Server (NTRS)

    Yang, Ping; Bi, Lei; Baum, Bryan A.; Liou, Kuo-Nan; Kattawar, George W.; Mishchenko, Michael I.; Cole, Benjamin

    2013-01-01

    A data library is developed containing the scattering, absorption, and polarization properties of ice particles in the spectral range from 0.2 to 100 microns. The properties are computed based on a combination of the Amsterdam discrete dipole approximation (ADDA), the T-matrix method, and the improved geometric optics method (IGOM). The electromagnetic edge effect is incorporated into the extinction and absorption efficiencies computed from the IGOM. A full set of single-scattering properties is provided by considering three-dimensional random orientations for 11 ice crystal habits: droxtals, prolate spheroids, oblate spheroids, solid and hollow columns, compact aggregates composed of eight solid columns, hexagonal plates, small spatial aggregates composed of 5 plates, large spatial aggregates composed of 10 plates, and solid and hollow bullet rosettes. The maximum dimension of each habit ranges from 2 to 10,000 microns in 189 discrete sizes. For each ice crystal habit, three surface roughness conditions (i.e., smooth, moderately roughened, and severely roughened) are considered to account for the surface texture of large particles in the IGOM applicable domain. The data library contains the extinction efficiency, single-scattering albedo, asymmetry parameter, six independent nonzero elements of the phase matrix (P11, P12, P22, P33, P43, and P44), particle projected area, and particle volume to provide the basic single-scattering properties for remote sensing applications and radiative transfer simulations involving ice clouds. Furthermore, a comparison of satellite observations and theoretical simulations for the polarization characteristics of ice clouds demonstrates that ice cloud optical models assuming severely roughened ice crystals significantly outperform their counterparts assuming smooth ice crystals.

  20. The effect of modification procedures on rigid gas permeable contact lenses: the UM-St. Louis Study.

    PubMed

    Morgan, B W; Henry, V A; Bennett, E S; Caroline, P J

    1992-03-01

    The purpose of this study is to evaluate the effect of frequently performed modification procedures on quality of vision, surface wettability, optical quality and subjective response. One subject was optimally fitted with both silicone/acrylate (S/A) and fluoro-silicone/acrylate (F-S/A) lens materials of identical design. Two methods of surface polishing, edge polishing and repowering were used in addition to three different spindle speeds. Each pair of lenses was worn by the subject for a period of 4 hours and the subjective response was then compared to the baseline or premodification data. In addition, both low magnification photography and Scanning Electron Microscopy (S.E.M.) were performed on each lens. The results showed that the addition of 0.50D minus power reduced visual acuity, contrast sensitivity function and optical quality with one of the methods used. Front surface polish and edge polish procedures did not appear to affect short-term performance. Controlling polish, application and tool pressure on certain procedures resulted in similar findings. Further studies would be beneficial to evaluate the effect of longer wearing periods and the use of other modification procedures. The authors conclude that S/A and F-S/A lens materials can be successfully modified in-office with adherence to recommended guidelines.

  1. Genetic mapping of MlUM15: an Aegilops neglecta-derived powdery mildew resistance gene in common wheat

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Powdery mildew, caused by Blumeria graminis DC f. sp. tritici, is a major fungal disease of wheat (Triticum aestivum L.) in cool and humid climates. Race-specific host plant resistance is a reliable, economical, and environmentally benign form of disease prevention. The identification of molecular m...

  2. The relationship between English language learning strategies and gender among pre-university students: An overview of UMS

    NASA Astrophysics Data System (ADS)

    Kiram, Johannah Jamalul; Sulaiman, Jumat; Swanto, Suyansah; Din, Wardatul Akmam

    2014-06-01

    This study aims to analyze the effects psychological gender differences on the relationship between language learning strategies and their proficiency in English language for pre-university students. Previous researchers found that the more employment of language learning strategies, the more successful the learners are and those with higher level of strategy use are female rather than male. In this study, fifty-six pre-university students (22 males, 34 females) of University Malaysia Sabah participated in this study. Oxford's Strategy Inventory for Language Learning (SILL) self-report questionnaire was adopted to identify the students' language learning strategies, whereas their proficiencies were based on their Malaysian University English Test (MUET) results. Pearson's correlation coefficient, one-way analysis of variance (ANOVA) and the t-test were utilized to make statistical interpretation about the relationship. The knowledge obtained from this study will be helpful for future studies on how to improve the quality of learning and proficiency in English.

  3. VizieR Online Data Catalog: Galaxy structural parameters from 3.6um images (Kim+, 2014)

    NASA Astrophysics Data System (ADS)

    Kim, T.; Gadotti, D. A.; Sheth, K.; Athanassoula, E.; Bosma, A.; Lee, M. G.; Madore, B. F.; Elmegreen, B.; Knapen, J. H.; Zaritsky, D.; Ho, L. C.; Comeron, S.; Holwerda, B.; Hinz, J. L.; Munoz-Mateos, J.-C.; Cisternas, M.; Erroz-Ferrer, S.; Buta, R.; Laurikainen, E.; Salo, H.; Laine, J.; Menendez-Delmestre, K.; Regan, M. W.; de Swardt, B.; Gil de Paz, A.; Seibert, M.; Mizusawa, T.

    2016-03-01

    We select our samples from the Spitzer Survey of Stellar Structure in Galaxies (S4G; Sheth et al. 2010, cat. J/PASP/122/1397). We chose galaxies that had already been processed by the first three S4G pipelines (Pipelines 1, 2, and 3; Sheth et al. 2010, cat. J/PASP/122/1397) at the moment of this study (2011 November). In brief, Pipeline processes images and provides science-ready images. Pipeline 2 prepares mask images (to exclude foreground and background objects) for further analysis, and Pipeline 3 derives surface brightness profiles and total magnitudes using IRAF ellipse fits. We excluded highly inclined (b/a<0.5), significantly disturbed, very faint, or irregular galaxies. Galaxies were also discarded if their images are unsuitable for decomposition due to contamination such as a bright foreground star or significant stray light from stars in the IRAC scattering zones. Then we chose barred galaxies from all Hubble types from S0 to Sdm using the numerical Hubble types from Hyperleda (Paturel et al. 2003, cat. VII/237, VII/238). The assessment of the presence of a bar was done visually by K. Sheth, T. Kim, and B. de Swardt. Later, we also confirmed the presence of a bar by checking the mid-infrared classification (Buta et al. 2010, cat. J/ApJS/190/147; Buta et al. 2015, cat. J/ApJS/217/32). A total of 144 barred galaxies were selected that satisfy our criteria, and we list our sample in Table1 with basic information. Table2 presents the measures of structural parameters for all galaxies in the sample obtained from the 2D model fit with BUDDA (BUlge/disk Decomposition Analysis, de Souza et al., 2004ApJS..153..411D; Gadotti, 2008MNRAS.384..420G) code. (2 data files).

  4. Observation of nonlinear optical phenomena in fused silica and air using a 100 GW, 1.54 um source.

    SciTech Connect

    Rudd, James Van; Law, R. J.; Luk, Ting Shan; Naudeau, Madeline L.; Nelson, Thomas Robert; Cameron, Stewart M.

    2006-02-01

    A 100-GW optical parametric chirped-pulse amplifier system is used to study nonlinear effects in the 1.54 {micro}m regime. When focusing this beam in air, strong third-harmonic generation (THG) is observed, and both the spectra and efficiency are measured. Broadening is observed on only the blue side of the third-harmonic signal and an energy conversion efficiency of 0.2% is achieved. When propagated through a 10-cm block of fused silica, a collimated beam is seen to collapse and form multiple filaments. The measured spectral features span 400-2100 nm. The spectrum is dominated by previously unobserved Stokes emissions and broad emissions in the visible.

  5. Accelerated Decompression from Saturation at 132 Feet of Sea Water With Isobaric oxygenation at 60 Feet of Sea Water

    DTIC Science & Technology

    2009-02-01

    catheterized with an external jugular catheter via the Seldinger technique and allowed to recover. Subjects were exposed to 132 feet of seawater (fsw) in...the external jugular vein of the animal was catheterized with a 16 gauge by 20.3 cm single lumen catheter (Braun Certofix; B. Braun Medical Inc... central cyanosis or the production of frothy white sputum. The onset of severe DCS (neurological or cardio-pulmonary dysfunction) and all behavioral

  6. Stenting of the superior vena cava and left brachiocephalic vein with preserving the central venous catheter in situ.

    PubMed

    Isfort, Peter; Penzkofer, Tobias; Goerg, Fabian; Mahnken, Andreas H

    2011-01-01

    Stenting of the central veins is well established for treating localized venous stenosis. The techniques regarding catheter preservation for central venous catheters in the superior vena cava have been described. We describe here a method for stent implantation in the superior vena cava and the left brachiocephalic vein, and principally via a single jugular venous puncture, while saving a left sided jugular central venous catheter in a patient suffering from central venous stenosis of the superior vena cava and the left brachiocephalic vein.

  7. Recent transmission of drug-resistant Mycobacterium tuberculosis in a prison population in southern Brazil.

    PubMed

    Reis, Ana Julia; David, Simone Maria Martini de; Nunes, Luciana de Souza; Valim, Andreia Rosane de Moura; Possuelo, Lia Gonçalves

    2016-01-01

    We conducted a cross-sectional, retrospective study, characterized by classical and molecular epidemiology, involving M. tuberculosis isolates from a regional prison in southern Brazil. Between January of 2011 and August of 2014, 379 prisoners underwent sputum smear microscopy and culture; 53 (13.9%) were diagnosed with active tuberculosis. Of those, 8 (22.9%) presented with isoniazid-resistant tuberculosis. Strain genotyping was carried out by 15-locus mycobacterial interspersed repetitive unit-variable-number tandem-repeat analysis; 68.6% of the patients were distributed into five clusters, and 87.5% of the resistant cases were in the same cluster. The frequency of drug-resistant tuberculosis cases and the rate of recent transmission were high. Our data suggest the need to implement an effective tuberculosis control program within the prison system. RESUMO Estudo transversal, retrospectivo, com isolados de M. tuberculosis de pacientes de um presídio regional no sul do Brasil, caracterizado através de epidemiologia clássica e molecular. Entre janeiro de 2011 e agosto de 2014, 379 detentos foram submetidos a baciloscopia e cultura, sendo 53 (13,9%) diagnosticados com tuberculose ativa. Desses, 8 (22,9%) apresentavam tuberculose resistente a isoniazida. A genotipagem das cepas foi realizada por 15-locus mycobacterial interspersed repetitive units-variable number of tandem repeat analysis; 68,6% dos pacientes estavam distribuídos em cinco clusters, e 87,5% dos casos resistentes estavam em um mesmo cluster. Verificou-se uma frequência elevada de casos de resistência e alta taxa de transmissão recente. Estes dados sugerem a necessidade da implantação de um programa efetivo de controle da tuberculose no sistema prisional.

  8. Which is the easiest and safest technique for central venous access? A retrospective survey of more than 5,400 cases.

    PubMed

    Pittiruti, M; Malerba, M; Carriero, C; Tazza, L; Gui, D

    2000-01-01

    There is an ongoing debate on the technique for central venous catheterization associated with the lowest complication rate and the highest success rate. In an attempt to better define the easiest and safest venous approach, we have reviewed our 7-year experience with 5479 central venous percutaneous punctures (by Seldinger's technique) for the insertion of short-term (n=2109), medium/long-term (n=2627) catheters, as well as double-lumen, large-bore catheters for hemodialysis and/or hemapheresis (n=743). We have analyzed the incidence of the most frequent in-sertion-related complications by comparing seven different venous approaches: jugular vein, low lateral approach; jugular vein, high lateral approach; jugular vein, low axial approach; subclavian vein, infraclavicular approach; subclavian vein, supraclavicular approach; external jugular vein; femoral vein. The results of our retrospective study suggest that the 'low lateral' approach to the internal jugular vein, as described by Jernigan and modified according to our protocol, appears to be the easiest and safest technique for percutaneous insertion of central venous access, being characterized by the lowest incidence of accidental arte-rial puncture (1.2%) and malposition (0.8%), no pneumothorax, and an extremely low rate of repeated attempts (i.e. more than two punctures before successful cannulation) (3.3%). We advocate the 'low lateral' approach to the internal jugular vein as first-choice technique for venipuncture in both adults and children, for both short-term and long-term central venous percutaneous cannulation.

  9. Calcitonin gene-related peptide immunoreactive sensory neurons in the vagal and glossopharyngeal ganglia innervating the larynx of the rat.

    PubMed

    Hayakawa, Tetsu; Kuwahara-Otani, Sachi; Maeda, Seishi; Tanaka, Koichi; Seki, Makoto

    2014-01-01

    We have examined whether calcitonin gene-related peptide-immunoreactive (CGRP-ir) neurons in the vagal and glossopharyngeal ganglia innervate the larynx. Many CGRP-ir neurons were located mostly in the superior glossopharyngeal-jugular ganglion complex that was fused the superior glossopharyngeal ganglion and the jugular ganglion in the cranial cavity. When Fluorogold was applied to the cut end of the superior laryngeal nerve (SLN) or the recurrent laryngeal nerve (RLN), many Fluorogold-labeled neurons were found in the superior glossopharyngeal-jugular ganglion complex and the nodose ganglion. Double-labeling for CGRP and Fluorogold showed that about 80% of Fluorogold-labeled neurons in the superior glossopharyngeal-jugular ganglion complex expressed CGRP-like immunoreactivity in the case of application to the SLN, and about 50% of Fluorogold-labeled neurons expressed CGRP-like immunoreactivity in the case of the RLN. Only a few double-labeled neurons were found in the nodose ganglion. The number of the Fluorogold-labeled neurons and double-labeled neurons in the superior glossopharyngeal-jugular ganglion complex in the case of the SLN was larger than that in the case of the RLN. These results indicate that sensory information from the larynx might be conveyed by many CGRP-ir neurons located in the superior glossopharyngeal-jugular ganglion complex by way of the SLN and the RLN.

  10. Heat capacities and entropies from 8 to 1000 K of langbeinite (K2Mg2(SO4)3), anhydrite (CaSO4) and of gypsum (CaSO4·2H2O)

    USGS Publications Warehouse

    Robie, Richard A.; Russell-Robinson, Susan; Hemingway, Bruce S.

    1989-01-01

    Although Bond (Bell Sys. Tech. J., 22 (1943) 145) reported that langbeinite was piezoelectric at room temperature, we found no evidence in our Cpo measurements for a Curie temperature above which langbeinite would no longer be piezoelectric.

  11. POBREZA Y VULNERABILIDAD EN MÉXICO: EL CASO DE LOS JÓVENES QUE NO ESTUDIAN NI TRABAJAN*

    PubMed Central

    Aguila, Emma; Mejía, Nelly; Pérez, Francisco; Rivera, Alfonso; Ramírez, Edgar

    2015-01-01

    La situación de los jóvenes que no estudian ni trabajan (ninis) se ha vuelto evidente en los últimos años debido a los riesgos que enfrenta dicha población. Este artículo contribuye a la literatura al analizar las características económicas y laborales de los ninis, explora la situación laboral de sus parejas y provee proyecciones al año 2030. Asimismo, propone una clasificación de ninis para focalizar el diseño de políticas públicas, que identifica una tendencia a la baja de éstos debido a las mujeres que acceden al sistema educativo y al mercado laboral y que una mayor proporción de esta población estará compuesta por desempleados. PMID:25918452

  12. Thyroid carcinoma in children and young adults: retrospective review of 19 cases.

    PubMed

    Saraiva, Joana; Ribeiro, Cristina; Melo, Miguel; Gomes, Leonor; Costa, Gracinda; Carrilho, Francisco

    2013-01-01

    Introdução: O carcinoma da tiróide é raro em crianças e em adultos jovens. A maior parte das orientações clínicas baseia-se em dados obtidos na população adulta. Persistem diversas controvérsias no que se refere à agressividade da apresentação clínica e da abordagem terapêutica.Objectivo: Avaliar todos os doentes com carcinoma da tiróide com menos de 20 anos no momento da apresentação, reflectindo a experiência da nossa unidade relativamente ao diagnóstico, tratamento e seguimento desta entidade.Material e Métodos: Trata-se de um estudo de revisão retrospectiva dos registos clínicos de todas as crianças e adultos jovens seguidos na Consulta de Oncologia do Serviço de Endocrinologia do Centro Hospitalar e Universitário de Coimbra entre 1996 e 2012 .Resultados: Foram estudados 19 doentes, com uma média etária de 16 anos, sendo 13 do sexo feminino. Nenhum dos doentes fora previamente submetido a irradiação da região do pescoço. A queixa de apresentação era a presença de uma massa cervical palpável em 84,6% dos casos. Foi realizada citologia aspirativa em 15 doentes, que foi diagnóstica ou suspeita de neoplasia em 71,4% dos casos. A tiroidectomia total foi levada a cabo em 18 casos (94,7%). Em todos estes foi identificada a presença de um carcinoma papilar. A invasão vascular e multicêntrica ocorreu em 21,1% dos casos. A dimensão tumoral média foi de 2,5 cm. O envolvimento ganglionar cervical foi diagnosticado em 31,6% dos casos e a presença de metástases à distância foi identificada em 5,2% dos casos. Na maior parte dos doentes (18 em 19), o quadro foi classificado como doença em estadio I. Todos os doentes fizeram terapêutica supressora com tiroxina e 84,2% dos doentes foram submetidos a ablação pós-operatória com iodo radioactivo (dose média de 85,7mCi). Durante um seguimento médio de cerca de 6 anos, 16 doentes permaneceram em remissão.Conclusão: Na nossa série, as taxas de metastização ganglionar cervical

  13. Discos de acresção em sistemas Be-X

    NASA Astrophysics Data System (ADS)

    Lopes de Oliveira, R.; Janot-Pacheco, E.

    2003-08-01

    Alguns fenômenos de outbursts em Be-X sugerem a existência, mesmo que temporária, de um disco de acresção quando da passagem do objeto compacto pelo periastro orbital. Neste trabalho avaliamos a possibilidade de formação do disco de acresção em sistemas Be+estrela de neutrons e Be+anã branca, e a influência da excentricidade orbital na ocorrência deste fenômeno. Utilizamos a expressão analítica para o momento angular específico da matéria constituinte de um meio em expansão lenta, como é o caso do disco circunstelar das estrelas Be, proposta por Wang(1981), sob a condição básica de que o raio de circularização deva ser maior do que o raio de Alfvén. Concluímos que existe um limite para o período orbital do sistema acima do qual não é possível a formação do disco de acresção, e que este valor aumenta para sistemas com excentricidade orbital maior.

  14. Giant gastric lipossarcoma: case report and review of the literature.

    PubMed

    Matone, Jacques; Okazaki, Samuel; Maccapani, Gabriel Naman; Amancio, Thiago Trolez; Filippi, Renée Zon; Macedo, Antonio Luiz de Vasconcellos

    2016-01-01

    Liposarcoma is one of the most common soft tissue sarcomas in adults, occurring in 15 to 20% of all patients with sarcoma. Primary liposarcoma of the stomach is rare. We report a case of patient with giant gastric liposarcoma who underwent surgery after a gastrointestinal bleeding. Preoperative hystopathological diagnosis was not established, even after three biopsy attempts. We discuss differential diagnosis, genetic causes, diagnosis strategies and treatment. RESUMO O lipossarcoma é um tipo comum de sarcomas em adultos, com incidência entre 15 e 20% entre os sarcomas. No entanto, o acometimento do estômago é raro. Relatamos um caso de um lipossarcoma primário gástrico gigante com apresentação clínica de hemorragia digestiva. Foi submetido a tratamento cirúrgico sem diagnóstico definitivo, apesar de três biópsias realizadas. Revisamos diagnósticos diferenciais, influência genética e estratégias diagnósticas e terapêuticas.

  15. Mumps Outbreak among Highly Vaccinated Teenagers and Children in the Central Region of Portugal, 2012-2013.

    PubMed

    Cordeiro, Eugénio; Ferreira, Muriel; Rodrigues, Fernanda; Palminha, Paula; Vinagre, Elsa; Pimentel, João Pedro

    2015-01-01

    Introdução: A vacina contra o sarampo, parotidite epidémica e rubéola foi introduzida no Programa Nacional de Vacinação em 1987, atingindo rapidamente uma cobertura vacinal > 92% para duas doses, com redução importante da incidência anual da doença. Reportamos um surto de parotidite na Região Centro de Portugal ocorrido entre outubro de 2012 e março de 2013. Material e Métodos: Foram investigados os casos de tumefação de glândulas salivares e sintomas compatíveis com parotidite. Para cada caso foram analisados dados demográficos, clínicos, laboratoriais e vacinais. Resultados: Ao longo de seis meses foram notificados 148 casos: 87,8% ocorreram em três dos 16 concelhos afetados e 78,4% tinham uma relação epidemiológica conhecida. A idade mediana foi de 14,5 anos (2-62) e 70,3% tinham entre 11 e 20 anos; 61,5% eram do sexo masculino. Na maioria dos casos a doença foi ligeira, com uma duração média de sete dias (2-20). A febre ocorreu em 80,4% e a glândula parótida apresentou envolvimento unilateral em 55,4%; sete casos tiveram orquite, um ooforite e uma nefrite. Dois doentes foram internados. A transmissão da doença ocorreu predominantemente em ambiente escolar, com taxas de ataque < 30%. A maioria dos casos ocorreu em indivíduos vacinados (92%), dos quais 86,8% com duas doses. Em 17,7% foi identificada uma dosede vacina contendo a estirpe Rubini. Foi identificado o genótipo G do vírus da parotidite em quatro casos. Discussão: Este surto de parotidite numa população com coberturas vacinais elevadas, atingindo principalmente adolescentes em meio escolar, poderá dever-se à efetividade parcial da vacina contra a doença (especialmente no grupo vacinado com a estirpe Rubini), à perda de imunidade ao longo do tempo ou ainda à discordância entre os genótipos vacinal e circulante causador de doença. Conclusões: O relato deste surto releva a importância da discussão sobre a necessidade de mais doses de reforço da vacina atual

  16. [Surgical Treated Spondylodiscitis Epidemiological Study].

    PubMed

    Soares do Brito, Joaquim; Tirado, António; Fernandes, Pedro

    2016-05-01

    Introdução: O termo espondilodiscite descreve uma qualquer infeção da coluna vertebral, sendo o tratamento gold standard baseado na terapêutica médica e a indicação cirúrgica ponderada em casos particulares. Foi objetivo deste trabalho estudar o perfil epide-miológico de um grupo de doentes com espondilodiscite submetidos a tratamento cirúrgico numa mesma instituição nacional entre 1997 e 2013. Material e Métodos: Análise epidemiológica de 85 doentes com diagnóstico de espondilodiscite submetidos a tratamento cirúrgico. Foram analisados os processos clínicos, estudos de imagem e registos informáticos. Resultados: Foram tratados 51 doentes do género masculino e 34 do género feminino. A idade média foi de 48 anos (min: 6 - máx: 80). O segmento lombar foi o mais afetado e o Mycobacterium tuberculosis o agente etiológico mais frequente. A distribuição do número de casos ao longo dos anos manteve-se aproximadamente constante, com discreto aumento da incidência do Staphylococus aureus e diminuição do número de casos sem agente identificado. Trinta e nove doentes apresentavam abcesso paravertebral e 17 lesão neurológica concomitante, a maioria no segmento torácico e em relação com infeção tuberculosa. Dez doentes apresentavam imunodepressão importante. Discussão: Nesta série verificou-se um predomínio da infeção tuberculosa, no género masculino e em indivíduos jovens. Enquanto o número de casos/ano das discites tuberculosas se mantém constante, as infeções a Staphylococus aureus parecem ganhar preponderância. O abcesso paravertebral e a lesão neurológica constituíram uma complicação frequente da infeção tuberculosa. Conclusão: As infeções da coluna vertebral com necessidade cirúrgica persistem como patologia relevante. Mycobacterium tuberculosis e Staphylococcus aureus representam os principais agentes etiológicos, parecendo existir uma incidência crescente deste último agente.

  17. [The Epidemiology of Dementia and Alzheimer Disease in Portugal: Estimations of Prevalence and Treatment-Costs].

    PubMed

    Santana, Isabel; Farinha, Filipa; Freitas, Sandra; Rodrigues, Vítor; Carvalho, Ålvaro

    2015-01-01

    Introdução: A incidência e prevalência de demência e de Doença de Alzheimer aumentam com a idade, duplicando a cada cinco anos após a sexta década de vida. Portugal é um país envelhecido, previsivelmente com um número crescente de casos de demência. No entanto, os dados epidemiológicos são escassos e os estudos sobre os custos da doença praticamente inexistentes. Propomo-nos apresentar uma estimativa actualizada da prevalência de demência/ Doença de Alzheimer em Portugal e inferir, a partir da prescrição específica para demência, o número de diagnósticos efectivos e os encargos financeiros com esses medicamentos.Material e Métodos: ÃÄ população residente em Portugal (2013), aplicámos os valores de prevalência de demência para a Europa Ocidental (estudo da AlzheimerâÄôs Disease International). A estimativa dos diagnósticos efectivos de Doença de Alzheimer e dos encargos financeiros com medicação específica baseou-se nas informações do Intercontinental Marketing Services Health (IMSH) âÄì 2013.Resultados: O número estimado de Portugueses com mais de 60 anos e com demência foi 160287, o que corresponde a 5,91% deste universo populacional. Sabendo que a Doença de Alzheimer representa 50-70% dos casos, inferimos que existirão entre 80144 e 112201 doentes. Por outro lado, os dados da IMSH indicam que estarão diagnosticados e a receceber anti-demenciais 76250 doentes, representando um encargo financeiro de 37 MâǬ/ano.Conclusão: O envelhecimento da população incrementa o número de casos de demência. Aparentemente, nem todos os doentes com Doença de Alzheimer recebem a medicação aconselhada, sugerindo que esta condição ainda está sub-diagnosticada. A evolução tem sido positiva, com incremento do número de doentes tratados e redução dos custos com fármacos específicos.

  18. Anatomical coverage in elective irradiation of the neck for squamous cell carcinoma of the oral tongue

    SciTech Connect

    Meoz, R.T.; Fletcher, G.H.; Lindberg, R.D.

    1982-11-01

    From January 1954 through December 1978, 146 patients with squamous cell carcinoma of the oral tongue and clinically negative neck had their primary lesion conrolled with irradiation. Metastases to the neck developed later in: 27 of 76 patients (36%) treated by interstitial implantation; nine of 27 patients (33%) who received 2,000 rad in five fractions to the upper neck prior to the implant; eight of 19 (42%) patients who received 5,000 rad through an upper ipsilateral neck field prior to the implant; four of 24 patients (16.6%) who received 5,000 rad through bilateral portals to the upper neck with or without irradiation of the lower neck. In the 43 ipsilateral neck failures, 23 were in the upper jugular chain, (posterior subdigastric nodes), 12 in the mid-jugular, three in the lower jugular, and four in the more anterior part of the subdigastric area. There was one failure in the posterior cervical chain, and five contralateral neck failures. A review of the treatment charts showed that the patients who had an ipsilateral upper neck field only, had smaller portals because the irradiation was tailored to produce shrinkage of the primary tumor prior to needling. To include adequate coverage of the posterior subdigastric nodes (upper jugular), the bodies of the vertebrae must be seen on the simulator films. Also the junction of the subdigastric and the mid-jugular lymphatics must be covered. Although there were only three failures in the lower jugular nodes, it is technically easier to treat the upper mid-jugular nodes through an anterior appositional portal to the lower neck. A dose of 5,000 rad must be given since 2,000 rad, even if delivered in five fractions, gives a failure rate as if there had been no irradiation to the neck.

  19. Anatomical coverage in elective irradiation of the neck for squamous cell carcinoma of the oral tongue

    SciTech Connect

    Meoz, R.T.; Fletcher, G.H.; Lindberg, R.D.

    1982-11-01

    From January 1954 through December 1978, 146 patients with squamous cell carcinoma of the oral tongue and clinically negative neck had their primary lesion controlled with irradiation. Metastases to the neck developed later in: 27 of 76 patients (36%) treated by interstitial implantation: nine of 27 patients (33%) who received 2,000 rad in five fractions to the upper neck prior to the implant; eight of 19 (42%) patients who received 5,000 rad through an upper ipsilateral neck field prior to the implant; four of 24 patients (16.6%) who received 5,000 rad through bilateral portals to the upper neck with or without irradiation of the lower neck. In the 43 ipsilateral neck failures, 23 were in the upper jugular chain, (posterior subdigastric nodes), 12 in the mid-jugular, three in the lower jugular, and four in the more anterior part of the subdigastric area. There was one failure in the posterior cervical chain, and five contralateral neck failures. A review of the treatment charts showed that the patients who had ipsilateral upper neck field only, had smaller portals because the irradiation was tailored to produce shrinkage of the primary tumor prior to needling. To include adequate coverage of the posterior subdigastric nodes (upper jugular), the bodies of the vertebrae must be seen on the simulator films. Also the junction of the subdigastric and the mid-jugular lymphatics must be covered. Although there were only three failures in the lower jugular nodes, it is technically easier to treat the upper mid-jugular nodes through an anterior appositional portal to the lower neck. A dose of 5,000 rad must be given since 2,000 rad, even if delivered in five fractions, gives a failure rate as if there had been no irradition to the neck.

  20. Splenic artery aneurysm.

    PubMed

    Tcbc-Rj, Rui Antônio Ferreira; Ferreira, Myriam Christina Lopes; Ferreira, Daniel Antônio Lopes; Ferreira, André Gustavo Lopes; Ramos, Flávia Oliveira

    2016-01-01

    Splenic artery aneurysms - the most common visceral artery aneurysms - are found most often in multiparous women and in patients with portal hypertension. Indications for treatment of splenic artery aneurysm or pseudoaneurysm include specific symptoms, female gender and childbearing age, presence of portal hypertension, planned liver transplantation, a pseudoaneurysm of any size, and an aneurysm with a diameter of more than 2.5cm. Historically, the treatment of splenic artery aneurysm has been surgical ligation of the splenic artery, ligation of the aneurysm, or aneurysmectomy with or without splenectomy, depending on the aneurysm location. There are other percutaneous interventional techniques. The authors present a case of a splenic artery aneurysm in a 51-year-old woman, detected incidentally. RESUMO Aneurismas da artéria esplênica - os aneurismas arteriais viscerais mais comuns - são encontrados mais frequentemente em mulheres multíparas e em pacientes com hipertensão portal. As indicações para o seu tratamento incluem sintomas específicos, sexo feminino e idade fértil, presença de hipertensão portal, paciente em fila de transplante hepático, um pseudoaneurisma de qualquer tamanho, e um aneurisma com um diâmetro superior a 2,5cm. Historicamente, o tratamento do aneurisma da artéria esplênica tem sido a ligadura cirúrgica da artéria esplênica, a ligadura do aneurisma ou a aneurismectomia, com ou sem esplenectomia, dependendo do local do aneurisma. Existem outras técnicas intervencionistas percutâneas. Os autores apresentam o caso de um aneurisma de artéria esplênica em uma mulher de 51 anos de idade, diagnosticado incidentalmente.

  1. [Mediterranean Spotted Fever: Retrospective Review of Hospitalized Cases and Predictive Factors of Severe Disease].

    PubMed

    Meireles, Mariana; Magalhães, Rui; Guimas, Arlindo

    2015-01-01

    Introdução: Febre escaro-nodular, uma zoonose antiga a levantar questões actuais. Este estudo pretende reavaliar a imagem clínica da doença e identificar factores prognósticos de doença severa. Material e Métodos: Foram avaliados os casos admitidos num hospital central no período de 12 anos. Os fatores de risco foram determinados por análise uni e multivariada, comparando os indivíduos internados em enfermaria geral versus admitidos em unidades de cuidados intermédios/intensivos ou em caso de morte. Resultados: Foram revistos 71 casos de febre escaro-nodular. A média de idades foi 63,3 ± 16,7 anos e 52,1% eram homens. A escara de inoculação foi identificada em 62,0% dos casos. Febre e exantema foram os achados clínicos mais frequentes. Quarenta e cinco por cento dos doentes desenvolveram complicações e 22,5% foram internados em unidades de cuidados intermédios e/ou intensivos. Apirexia, dispneia, insuficiência renal e níveis de lactato desidrogenase elevados à admissão foram preditores de desenvolvimentode doença severa (p < 0,034). O alcoolismo associou-se a um tempo de internamento prolongado (p = 0,020). Ausênciade febre (p = 0,019) e níveis elevados de creatinina (p = 0,028) constituíram fatores independentes de mau prognóstico. A taxa de mortalidade foi 2,8%.Discussão: Apesar da evolução da febre escaro-nodular ser, geralmente, assumida como benigna, casos graves têm surgido. Quase metade dos doentes hospitalizados desenvolveu complicações. Apirexia e lesão renal predispõem a pior prognóstico. Conclusão: A identificação precoce da infeção e a vigilância contínua dos doentes são determinantes, particularmente naqueles com maior risco de desenvolverem doença severa ou fatal.

  2. Causes of Death in an Acute Psychiatric Inpatient Unit of a Portuguese General Hospital.

    PubMed

    Barbosa, Sofia; Sequeira, Márcia; Castro, Sara; Manso, Rita; Klut Câmara, Catarina; Trancas, Bruno; Borja-Santos, Nuno; Maia, Teresa

    2016-08-01

    Introdução: Os doentes afectos de patologia psiquiátrica apresentam maior risco de morte, tanto por causas naturais como não naturais. Este estudo avalia as causas de morte de todos os doentes de uma unidade de internamento de agudos de Psiquiatria num hospital geral em Portugal, ao longo de dezasseis anos (de 1998 a 2013). Material e Métodos: Vinte e um doentes morreram na unidade de internamento de doentes agudos entre 1998 e 2013 (média 1,3 por ano). As características demográficas, os diagnósticos médicos e psiquiátricos foram recolhidos através de um estudo retrospectivo que consistiu na análise dos processos clínicos da amostra selecionada. Os doentes transferidos para outras enfermarias durante o internamento não foram incluídos no estudo. Resultados: As doenças do sistema circulatório foram as causas de morte mais prevalentes, ocorrendo em 2/3 dos doentes, incluindo embolismo pulmonar (n = 6), acidente vascular cerebral (n = 3), arritmia cardíaca (n = 2), enfarte agudo do miocárdio (n = 1), rutura de aneurisma da aorta abdominal (n = 1) e insuficiência cardíaca (n = 1). Dois doentes morreram de pneumonia e em quatro casos a causa de morte foi indeterminada. Apenas um caso de suicídio foi registado. Discussão: As doenças do aparelho circulatório foram as causas de morte mais frequentes nesta unidade de agudos. O suicídio em doentes internados, apesar de constituir um evento raro, é uma realidade que comporta consequências complexas para os profissionais de saúde, familiares e restantes doentes, devendo permanecer como foco de prevenção continuada. Conclusão: Os estudos de mortalidade são importantes para determinar a qualidade dos cuidados de saúde e criar recomendações para medidas preventivas.

  3. [Cutaneous malignant melanoma: a retrospective study of seven years (2006-2012)].

    PubMed

    Moreira, Jorge; Moreira, Elisabete; Azevedo, Filomena; Mota, Alberto

    2014-01-01

    Introdução: O melanoma maligno é a neoplasia cutânea mais agressiva, e a sua incidência tem vindo a aumentar nas últimas décadas. A possibilidade de cura depende de um diagnóstico atempado, sendo fundamental o conhecimento da sua epidemiologia para a implementação de programas de prevenção primária e deteção precoce do melanoma. Material e Métodos: Foi efetuada revisão dos processos clínicos dos doentes com melanoma maligno cutâneo primário, diagnosticados entre janeiro de 2006 e dezembro de 2012, no Centro Hospitalar de São João, Porto. Resultados: Analisaram-se os 148 casos de melanoma diagnosticados neste período, tendo-se observado um predomínio do sexo feminino (razão F:M - 1,6:1). A média etária na altura do diagnóstico foi de 61 anos. As localizações mais frequentemente envolvidas foram os membros inferiores e o tronco. No sexo masculino o dorso foi o local mais afetado, enquanto no sexo feminino as lesões ocorreram, preferencialmente, nas pernas. O melanoma de extensão superficial foi o subtipo predominante em quase todas as faixas etárias. Verificou-se um predomínio dos melanomas finos e o índice mitótico foi intermédio (1-6 mitoses/ mm2) na maioria dos doentes. A ulceração esteve presente em 22,3% dos casos e predominou nos melanomas espessos e no subtipo nodular. A maioria dos doentes encontrava-se no estádio IA. A progressão para doença metastática ocorreu em 20 doentes. Discussão: O perfil do doente com melanoma cutâneo, no Centro Hospitalar de São João, apresenta características relativamente semelhantes às descritas na literatura. Conclusão: O predomínio dos melanomas finos, considerados de melhor prognóstico, é provavelmente, o resultado de um diagnóstico cada vez mais precoce.

  4. Como os Alunos do Ensino Médio da Rede Estadual de São Paulo obtém Conhecimentos Astronômicos?

    NASA Astrophysics Data System (ADS)

    da Cunha, W. S.; Voelzke, M. R.; Amaral, L. H.

    2005-08-01

    Atualmente vivencia-se um mundo globalizado onde os computadores e a internet permitiram um acesso rápido e seguro a todo tipo de informação e conhecimento. O presente trabalho visa analisar a maneira pela qual alunos de segundo grau da rede estadual da cidade de São Paulo obtiveram, caso tenham, conhecimentos básicos de astronomia quanto aos fenômenos celestes que os rodeiam, tais como a sucessão dos dias e das estações do ano, além de questioná~los sobre fatos genéricos tais como: o que vem a ser o Sol, o Big Bang, o que ocasionou a extinção dos dinossauros. Para tanto foi elaborado um formulário constando de questões de múltipla escolha, o qual foi aplicado no primeiro colegial diurno da Escola Estadual Guilherme de Almeida. Num espaço amostral de 44 alunos constatou-se que 41% dos alunos adquiriram seus conhecimentos astronômicos na escola e 59% através da mídia em geral. Neste mesmo espaço amostral apenas 11% dos alunos usaram computadores na escola, 41% na residência, 5% no trabalho e 43% não utilizaram. O presente estudo revelou também que para 50% dos alunos o professor jamais utilizou um programa de computador a respeito de astronomia ou fez alguma apresentação sobre o tema. Embora em sua fase inicial este estudo revela claramente que a maioria dos alunos não obtém na escola seus conhecimentos astronômicos, estes provém de fontes não especificamente didático-pedagógicas tais como filmes e revistas populares que não raramente geram conhecimentos incompletos e em muitos casos inclusive falhos.

  5. [Laparoscopic surgery of gastroesophageal reflux in children].

    PubMed

    Dias, Ana; Amaral, Marina; Trindade, Eunice; Dias, Jorge Amil; Campos, Miguel; Estevão-Costa, José

    2013-01-01

    Introdução: O refluxo gastroesofágico na criança é frequente e geralmente inócuo. Contudo, perante doença de refluxo gastroesofágico pode impor-se o tratamento cirúrgico, o qual pode ser realizado por via clássica ou laparoscópica. No presente estudo pretende-se avaliar a exequibilidade, eficácia e segurança da cirurgia antirrefluxo (fundoplicatura de Nissen) por via laparoscópica com ênfase no recém-nascido, lactente e primeira infância.Material e Métodos: Estudaram-se as crianças com refluxo gastroesofágico propostas para cirurgia por via laparoscópica entre janeiro 2006 e dezembro 2012 num Serviço de Cirurgia Pediátrica de um Hospital universitário. Realizou-se uma análise descritiva e comparativa por faixa etária (grupo I: <1 ano, grupo II: 1-3 anos, grupo III: > 3 anos) e presença de comorbilidades. Foram avaliados os seguintes parâmetros: demografia, sintomatologia, comorbilidades, indicações operatórias, perioperatório e evolução pós-operatória. Foi assumido um nível de significância de 5%.Resultados: Foram propostas 55 crianças, das quais 12 do grupo I, 15 do grupo II e 28 do grupo III. 50,9% apresentavam comorbilidades (21 com doença do sistema nervoso central e sete com atresia esofágica). Em 52 (94,5%) casos, a cirurgia foi exequível exclusivamente por via laparoscópica. A duração do procedimento foi de 167 ± 42 minutos, sem diferenças significativas entre grupos etários, mas superior na doença do sistema nervoso central. Com um seguimento de 35,5 ± 23,9 meses, ocorreram as seguintes complicações: síndrome de gas-bloat, dumping e disfagia em oito casos (15,7%) e hérniaparaesofágica em dois casos (3,9%), sem diferenças significativas entre os grupos; verificou-se recidiva clínica com reoperação em dois casos.Conclusão: A fundoplicatura de Nissen laparoscópica é um procedimento exequível, eficaz e com baixa morbilidade, inclusive em recém-nascidos, lactentes e na primeira infância.

  6. Acute Ischemic Stroke on Cancer Patients, a Distinct Etiology? A Case-Control Study.

    PubMed

    Carrilho Romeiro, Ana; Valadas, Anabela; Marques, José

    2015-01-01

    Introdução: Actualmente ainda não se encontra claramente definido se a etiologia do acidente vascular cerebral isquémico agudo difere entre doentes com e sem cancro. O acidente vascular cerebral isquémico e o cancro apresentam factores de risco comuns. No entanto, a literatura sugere que os doentes com cancro apresentam condições específicas que aumentam o risco de acidente vascular cerebral. O nosso objectivo foi comparar a etiologia do acidente vascular cerebral isquémico entre doentes com cancro e sem cancro. Material e Métodos: Estudo de caso-controlo realizado em doentes internados numa Unidade de acidente vascular cerebral entre Janeiro de 2007 e Dezembro de 2012. Os casos foram definidos como doentes com o diagnóstico concomitante de acidente vascular cerebral isquémico agudo e cancro; os controlos apenas com o diagnóstico de acidente vascular cerebral. Foram comparados entre os grupos: idade, género, factores de risco vasculares e etiologia do acidente vascular cerebral. Resultados: Foram identificados 56 casos, 64,3% do género masculino, com idade média de 71 anos; 21 doentes apresentavam doença neoplásica activa. O cancro gastrointestinal (25,9%) foi o mais frequente. Foram incluídos 151 controlos, emparelhados para a idade e género. A comparação dos factores de risco vasculares entre casos e controlos não revelou diferenças estatisticamente significativas, excepto para a diabetes mellitus, mais frequente no grupo de controlo (16,1% vs 33,8%, p = 0,02). A presença de história de eventos trombóticos prévios foi mais frequente na coorte de doentes com doença neoplásica (8,9% vs 0,7%, p = 0,007). O subtipo de etiologia do acidente vascular cerebral (classificação TOAST) âoutra etiologiaâ foi mais frequente nos doentes com cancro (13,04% vs 0,83%, p < 0,01), e a presença de um estado pró-trombótico foi mais frequente nos doentes com neoplasia activa.Discussão: Os resultados obtidos no nosso estudo permitiram definir dois

  7. Closure of the sigmoid sinus in lateral skull base surgery.

    PubMed

    Zanoletti, E; Cazzador, D; Faccioli, C; Martini, A; Mazzoni, A

    2014-06-01

    Closure of the sigmoid-jugular complex is generally planned during various surgical procedures on the skull base, either to repair a jugular foramen lesion or as the oncological boundary of the resection. A series of 218 cases of skull base tumour surgeries was analysed in which closure of the sigmoid-jugular complex was systematically planned (bilaterally in one case) in patients treated for jugular foramen paragangliomas, squamous cell carcinomas and other temporal bone tumours. Surgery was performed via a petro-occipital trans-sigmoid approach in 61 cases, an infratemporal A in 128, en bloc subtotal temporal bone resections in 10 and other approaches in 20. In our experience, planned unilateral (and, in one case, bilateral) closure of the sigmoid-jugular complex had no clinical consequences. The vicarious drainage of the skull base was always assessed preoperatively, revealing no contraindications to intraoperative sinus closure. Given the scarcity of literature on this subject, the present report shows that the procedure is associated with low morbidity and helps to improve our understanding of cerebral venous discharge.

  8. Venous catheterization with ultrasound navigation

    SciTech Connect

    Kasatkin, A. A. Nigmatullina, A. R.; Urakov, A. L.

    2015-11-17

    By ultrasound scanning it was determined that respiratory movements made by chest of healthy and sick person are accompanied by respiratory chest rise of internal jugular veins. During the exhalation of an individual diameter of his veins increases and during the breath it decreases down to the complete disappearing if their lumen. Change of the diameter of internal jugular veins in different phases can influence significantly the results of vein puncture and cauterization in patients. The purpose of this research is development of the method increasing the efficiency and safety of cannulation of internal jugular veins by the ultrasound visualization. We suggested the method of catheterization of internal jugular veins by the ultrasound navigation during the execution of which the puncture of venous wall by puncture needle and the following conduction of J-guide is carried out at the moment of patient’s exhalation. This method decreases the risk of complications development during catheterization of internal jugular vein due to exclusion of perforating wound of vein and subjacent tissues and anatomical structures.

  9. [Diagnosis recommendations for late-onset Pompe disease].

    PubMed

    Brito-Avô, Luis; Alves, José Delgado; Costa, João Matos; Valverde, Ana; Santos, Lélita; Araújo, Francisco; Aguiar, Patrício; Marinho, António; Oliveira, Anabela; Gomes, Daniel

    2014-01-01

    Introdução: A Doença de Pompe é uma miopatia autossómica recessiva progressiva e incapacitante, devida ao défice da enzima lisossómica a-glicosidade-ácida. A sua forma tardia tem uma apresentação heterogénea que mimetiza outras doenças neuromusculares, o que dificulta o diagnóstico. Objectivo: Desenvolver recomendações baseadas em consenso para o diagnóstico da forma tardia da doença de Pompe. Material e Métodos: Revisão bibliográfica e análise de um questionário de opinião aplicado a um grupo de especialistas com experiência no diagnóstico de várias miopatias e doenças de sobrecarga lisossomal. Discussão em reunião de consenso. Recomendações: Doentes com miopatia proximal progressiva, fadiga, cãibras e mialgias devem ser submetidos a uma avaliação complementar com determinação de níveis de creatinina fosfoquinase, electromiograma, espirometria dinâmica e, em casos inconclusivos, biópsia muscular. Nos casos suspeitos ou naqueles em que a biópsia muscular não permita outro diagnóstico deve ser determinada a atividade da enzima lisossómica a-glicosidade-ácida através de teste de gota seca (DBS – dried blood spot). A redução da atividade da enzima lisossómica a-glicosidade-ácida requer a confirmação numa segunda amostra e a sequenciação do gene da enzima lisossómica a-glicosidade-ácida.

  10. Busca de estruturas em grandes escalas em altos redshifts

    NASA Astrophysics Data System (ADS)

    Boris, N. V.; Sodrã©, L., Jr.; Cypriano, E.

    2003-08-01

    A busca por estruturas em grandes escalas (aglomerados de galáxias, por exemplo) é um ativo tópico de pesquisas hoje em dia, pois a detecção de um único aglomerado em altos redshifts pode por vínculos fortes sobre os modelos cosmológicos. Neste projeto estamos fazendo uma busca de estruturas distantes em campos contendo pares de quasares próximos entre si em z Â3 0.9. Os pares de quasares foram extraídos do catálogo de Véron-Cetty & Véron (2001) e estão sendo observados com os telescópios: 2,2m da University of Hawaii (UH), 2,5m do Observatório de Las Campanas e com o GEMINI. Apresentamos aqui a análise preliminar de um par de quasares observado nos filtros i'(7800 Å) e z'(9500 Å) com o GEMINI. A cor (i'-z') mostrou-se útil para detectar objetos "early-type" em redshifts menores que 1.1. No estudo do par 131046+0006/J131055+0008, com redshift ~ 0.9, o uso deste método possibilitou a detecção de sete objetos candidatos a galáxias "early-type". Num mapa da distribuição projetada dos objetos para 22 < i' < 25 observou-se que estas galáxias estão localizadas próximas a um dos quasares e há indícios de que estejam aglomeradas dentro de um área de ~ 6 arcmin2. Se esse for o caso, estes objetos seriam membros de uma estrutura em grande escala. Um outro argumento em favor dessa hipótese é que eles obedecem uma relação do tipo Kormendy (raio equivalente X brilho superficial dentro desse raio), como a apresentada pelas galáxias elípticas em z = 0.

  11. Adverse events with the influenza A(H1N1) vaccine Pandemrix® at healthcare professionals in Portugal.

    PubMed

    Marques, Joana Isabel; Ribeiro Vaz, Inês; Santos, Cristina; Polónia, Jorge

    2013-01-01

    Introdução: Os profissionais de saúde foram um grupo prioritário para vacinação contra a pandemia da Gripe A (H1N1), Pandemrix®. Assim, monitorizar os eventos adversos relacionados com esta vacina neste grupo específico poderá originar informação valiosa relacionada com o perfil de segurança da vacina. O nosso objetivo foi identificar os eventos adversos após imunização com a vacina Pandemrix® em profissionais de saúde. Material e Métodos: Foi desenhado um questionário de monitorização dos eventos adversos ocorridos com a vacina Pandemrix®. O questionário foi distribuído aos profissionais de saúde a trabalhar em três centros hospitalares da região norte do País, vacinados no período de 26 de Outubro de 2009 a 31 de janeiro de 2009. Resultados: Dos 2358 profissionais de saúde que aceitaram participar no estudo, 864 (37%) devolveram o questionário preenchido. Destes, 73% experienciaram pelo menos um evento adverso após imunização, mas só 8% experienciaram um evento inesperado. Os eventos adversos mais frequentemente reportados foram os esperados e muito comuns: reações locais no local de administração (57%), mialgia (31%), fadiga (incluindo astenia) (24%) e dor de cabeça (19%). Não foram reportados casos de eventos de maior gravidade para a saúde, tais como morte ou risco de vida. O género feminino e a existência de doença de base foram fatores de risco independentes para o desenvolvimento de pelo menos um evento adverso após imunização com a Pandemrix®. Conclusões: O nosso trabalho sugere um perfil de segurança aceitável da vacina pandémica Pandermix® em profissionais de saúde. Tanto a frequência como a severidade dos eventos adversos não se verificaram superiores ao esperado.

  12. Transferências orbitais dentro do modelo quase bicircular no sistema Terra-Lua-Sol

    NASA Astrophysics Data System (ADS)

    Corrêa, A. A.; de Almeida Prado, A. F. B.; Stuchi, T. J.; Beaugé, C.

    2003-08-01

    O problema quase bicircular planar consiste na determinação da dinâmica de um corpo, de massa desprezível, que se move sob o campo gravitacional de três corpos. No caso estudado, o quarto corpo é considerado um satélite artificial e os demais são a Terra, a Lua e o Sol, formando o sistema de três corpos. Este modelo permite a construção de uma hamiltoniana similar a do problema restrito de três corpos (PRTC), incluindo termos periódicos não autônomos, provenientes da presença do Sol, portanto pode ser entendido como uma perturbação ao PRTC. Suas órbitas periódicas aparecem isoladas e possuem o mesmo período solar. Os pontos de equilíbrio colineares possuem o mesmo caráter de estabilidade linear dos pontos lagrangianos (L1, L2 e L3) do PRTC, sendo do tipo sela x centro x centro, instável na direção x e estáveis nas direções y e z. As órbitas periódicas tridimensionais ao redor do ponto colinear é chamada órbita Halo. O objetivo deste trabalho é determinar órbitas de transferências de baixo consumo de combustível para um veículo espacial partindo de uma órbita de estacionamento ao redor da Terra em direção a uma órbita Halo do ponto L1, situado entre a Terra e Lua. Esta tarefa pode ser transformada no problema de valor de contorno: dado um ponto inicial na órbita de estacionamento, um ponto final na órbita halo e o tempo de transferência, deseja-se obter a trajetória que liga estes dois pontos e que minimize os incrementos de velocidade do veículo. Essas transferências são realizadas baseadas no método de Lambert e analisadas de modo a fornecer um baixo consumo. Posteriormente, é feita uma comparação de consumo com as órbitas de transferência equivalentes do PRTC.

  13. Rare case of nephrotic syndrome: Schimke syndrome.

    PubMed

    Pedrosa, Anna Kelly Krislane de Vasconcelos; Torres, Luiz Fernando Oliveira; Silva, Ana Corina Brainer Amorim da; Dantas, Adrianna Barros Leal; Zuntini, Káthia Liliane da Cunha Ribeiro; Aguiar, Lia Cordeiro Bastos

    2016-01-01

    Schimke syndrome corresponds to dysplasia of bone and immunity, associated with progressive renal disease secondary to nephrotic syndrome cortico-resistant, with possible other abnormalities such as hypothyroidism and blond marrow aplasia. It is a rare genetic disorder, with few reports in the literature. The most frequent renal involvement is nephrotic syndrome with focal segmental glomerulosclerosis and progressive renal failure. The objective of this study was to report a case of Schimke syndrome, diagnostic investigation and management of the case. Resumo A síndrome Schimke corresponde à displasia imuno-óssea, associada à doença renal progressiva secundária à síndrome nefrótica córtico-resistente, podendo haver outras anormalidades como hipotireoidismo e aplasia de medula óssea. Trata-se de uma patologia genética rara, com poucos relatos na literatura. O acometimento renal mais frequente é uma síndrome nefrótica por glomeruloesclerose segmentar e focal e falência renal progressiva. O objetivo deste estudo foi relatar um caso de síndrome de Schimke, investigação diagnóstica e condução do caso.

  14. Hypertriglyceridemia: Is there a role for prophylactic apheresis? A case report.

    PubMed

    Francisco, Ana Rita; Gonçalves, Inês; Veiga, Fátima; Pedro, Mónica Mendes; Pinto, Fausto J; Brito, Dulce

    2016-01-01

    Severe hypertriglyceridemia has been consistently associated with an increased risk of cardiovascular disease and other complications, namely acute pancreatitis. We report a case of a 64 year-old woman with hypertrophic cardiomyopathy and metabolic syndrome with triglyceride level of 3260 mg/dL. Plasma exchange was performed with simultaneous medical treatment to achieve a rapid and effective lowering of triglycerides in order to prevent clinical complications. After three plasmapheresis sessions a marked reduction in triglyceride and total cholesterol levels was observed. Several cases have shown the importance of plasmapheresis in the treatment of acute pancreatitis. We intend to demonstrate the applicability of this technique as primary prophylaxis in the presence of extremely high serum triglyceridemia levels. Resumo A hipertrigliceridemia grave tem sido associada de forma consistente ao aumento do risco cardiovascular e a outras complicações, nomeadamente, pancreatite aguda. Descrevemos um caso de uma mulher de 64 anos, com miocardiopatia hipertrófica e síndrome metabólica com valor sérico de triglicerídeos de 3260 mg/dL. Foi efectuada plasmaferese e optimizado o tratamento médico para alcançar uma redução rápida e efectiva dos níveis dos triglicerídeos, prevenindo complicações clínicas. Após três sessões de plasmaferese, verificou-se uma redução marcada dos triglicerídeos e do colesterol total. Existem alguns casos descritos na literatura demonstrado a importância da plasmaferese no tratamento da pancreatite aguda em contexto de hipertrigliceridemia grave. Os autores pretendem com este caso demonstrar a aplicabilidade desta técnica em contexto de prevenção primária em doentes com níveis de triglicerídeos extremamente aumentados.

  15. Practical Aspects of Nontunneled and Tunneled Hemodialysis Catheters

    PubMed Central

    Clark, Edward; Kappel, Joanne; MacRae, Jennifer; Dipchand, Christine; Hiremath, Swapnil; Kiaii, Mercedeh; Lok, Charmaine; Moist, Louise; Oliver, Matthew; Miller, Lisa M.

    2016-01-01

    Nontunneled hemodialysis catheters (NTHCs) are typically used when vascular access is required for urgent renal replacement therapy. The preferred site for NTHC insertion in acute kidney injury is the right internal jugular vein followed by the femoral vein. When aided by real-time ultrasound, mechanical complications related to NTHC insertion are significantly reduced. The preferred site for tunneled hemodialysis catheters placement is the right internal jugular vein followed by the left internal jugular vein. Ideally, the catheter should be inserted on the opposite side of a maturing or planned fistula/graft. Several dual-lumen, large-diameter catheters are available with multiple catheter tip designs, but no one catheter has shown significant superior performance. PMID:28270920

  16. Practical Aspects of Nontunneled and Tunneled Hemodialysis Catheters.

    PubMed

    Clark, Edward; Kappel, Joanne; MacRae, Jennifer; Dipchand, Christine; Hiremath, Swapnil; Kiaii, Mercedeh; Lok, Charmaine; Moist, Louise; Oliver, Matthew; Miller, Lisa M

    2016-01-01

    Nontunneled hemodialysis catheters (NTHCs) are typically used when vascular access is required for urgent renal replacement therapy. The preferred site for NTHC insertion in acute kidney injury is the right internal jugular vein followed by the femoral vein. When aided by real-time ultrasound, mechanical complications related to NTHC insertion are significantly reduced. The preferred site for tunneled hemodialysis catheters placement is the right internal jugular vein followed by the left internal jugular vein. Ideally, the catheter should be inserted on the opposite side of a maturing or planned fistula/graft. Several dual-lumen, large-diameter catheters are available with multiple catheter tip designs, but no one catheter has shown significant superior performance.

  17. Lemierre's syndrome (necrobacillosis).

    PubMed

    Golpe, R; Marín, B; Alonso, M

    1999-03-01

    Lemierre's syndrome or postanginal septicaemia (necrobacillosis) is caused by an acute oropharyngeal infection with secondary septic thrombophlebitis of the internal jugular vein and frequent metastatic infections. Fusobacterium necrophorum is the most common pathogen isolated from the patients. The interval between the oropharyngeal infection and the onset of the septicaemia is usually short. The most common sites of septic embolisms are the lungs and joints, and other locations can be affected. A high degree of clinical suspicion is needed to diagnose the syndrome. Computed tomography of the neck with contrast is the most useful study to detect internal jugular vein thrombosis. Treatment includes intravenous antibiotic therapy and drainage of septic foci. The role of anticoagulation is controversial. Ligation or excision of the internal jugular vein may be needed in some cases.

  18. Lemierre's syndrome (necrobacillosis)

    PubMed Central

    Golpe, R.; Marin, B.; Alonso, M.

    1999-01-01

    Lemierre's syndrome or postanginal septicaemia (necrobacillosis) is caused by an acute oropharyngeal infection with secondary septic thrombophlebitis of the internal jugular vein and frequent metastatic infections. Fusobacterium necrophorum is the most common pathogen isolated from the patients. The interval between the oropharyngeal infection and the onset of the septicaemia is usually short. The most common sites of septic embolisms are the lungs and joints, and other locations can be affected. A high degree of clinical suspicion is needed to diagnose the syndrome. Computed tomography of the neck with contrast is the most useful study to detect internal jugular vein thrombosis. Treatment includes intravenous antibiotic therapy and drainage of septic foci. The role of anticoagulation is controversial. Ligation or excision of the internal jugular vein may be needed in some cases.


Keywords: Lemierre's syndrome; Fusobacterium necrophorum; necrobacillosis; septicaemia; oropharynx PMID:10448489

  19. Tão perto de casa, tão longe de nós: etnografia das novas margens no centro da urbe

    PubMed Central

    Fernandes, Por Luís

    2011-01-01

    Philippe Bourgois é, desde 2007, “Richard Perry University professor” no Departamento de Antropologia e de Medicina Familiar e de Práticas Comunitárias na Universidade da Pensilvânia. Esteve durante largos anos ligado ao Departamento de Antropologia, História e Medicina Social da Universidade da Califórnia, São Francisco. A publicação, em 1995, de In Search of Respect: Selling Crack in El Barrio1 projectaria o seu nome muito para além dos Estados Unidos: uma etnografia no coração porto-riquenho do Harlem, em torno dos actores e dos ambientes da venda de crack. Seguir-se-ia um longo trabalho de terreno em acampamentos de dependentes de heroína em São Francisco, orientando o seu trabalho para as formas mais radicais da pobreza e da marginalidade nos EUA. É deste trabalho de terreno que sai o seu último livro, Righteous Dopefiend2. Em Junho de 2007 esteve em Lisboa para participar na 3.a edição do “Ethnografeast”. Foi então que aproveitámos a oportunidade para ouvir um percurso invulgar contado pelo próprio: uma longa conversa no Hotel Zurique, cujo nome só vem ao caso por evocar o país onde passou uma parte da infância. PMID:22013286

  20. Confusion about a little observatory: the history of the first high school observatory (German Title: Verwirrung um eine kleine Sternwarte: Die Geschichte der ersten Chemnitzer Schulsternwarte )

    NASA Astrophysics Data System (ADS)

    Pfitzner, Elvira

    By means of a small watercolor, painted by a musicologist, the existence of the highschool observatory of Chemnitz was rediscovered. The small observatory was build in 1893 by means of funds and a donation: after WW I it was also used for popular education. During Nazi times, the observatory fell into neglect, and the mechanical damage made it impossible to put it back into operation after WW II The building was torn down in 1964 and forgotten.

  1. Historia Oral, Experiencias de Aprendizagem e Enraizamento Sociocultural--Um Projeto em Curso (Oral History, Learning Experiences, and Sociocultural Setting--A Project in Process).

    ERIC Educational Resources Information Center

    Vidigal, Luis

    1995-01-01

    Examines education and childhood in Portugal. Uses oral history methods in an educational context, exploring oral statements pedagogically. Considers these statements especially suitable to maintaining aspects of collective memory and social identity, reinforcing students' national and regional identities. Suggests this is very important in…

  2. Prolegomenos a um estudo da lingua brasileira nos terreiros de origem africana (Prolegomena to a Study of the Brazilian Language of the Voodoo Rites of African Origin).

    ERIC Educational Resources Information Center

    Megenney, William W.

    Determination of the authenticity of lexical items with Sub-Saharan origin in the voodoo rites of candomble and umbanda in Brazil requires establishing a socio-historical basis for the African diaspora and the current configuration of terreiros. The terreiros demonstrate varying linguistic repertoires according to their affiliation with candomble…

  3. VizieR Online Data Catalog: Combined ArTeMiS+SPIRE 350um image of NGC6334 (Andre+, 2016)

    NASA Astrophysics Data System (ADS)

    Andre, P.; Reveret, V.; Konyves, V.; Arzoumanian, D.; Tige, J.; Gallais, P.; Roussel, H.; Le Pennec, J.; Rodriguez, L.; Doumayrou, E.; Dubreuil, D.; Lortholary, M.; Martignac, J.; Talvard, M.; Delisle, C.; Visticot, F.; Dumaye, L.; De Breuck, C.; Shimajiri, Y.; Motte, F.; Bontemps, S.; Hennemann, M.; Zavagno, A.; Russeil, D.; Schneider, N.; Palmeirim, P.; Peretto, N.; Hill, T.; Minier, V.; Roy, A.; Rygl, K. L. J.

    2016-05-01

    High dynamic range dust continuum map of the NGC 6334 star-forming complex at 350 microns obtained by combining high-resolution ground-based observations taken with the ArTeMiS camera on the APEX telescope and Herschel Space Observatory data from the HOBYS key project (Motte et al., 2010A&A...518L..77M; Russeil et al. 2013A&A...554A..42R). The effective angular resolution is ~ 8" (HPBW). (2 data files).

  4. Derivation of a Large Isotopic Diffuse Sky Emission Component at 1.25 and 2.2um from the COBE/DIRBE Data

    NASA Astrophysics Data System (ADS)

    Sano, K.; Kawara, K.; Matsuura, S.; Kataza, H.; Arai, T.; Matsuoka, Y.

    2015-10-01

    Using all-sky maps obtained with COBE/DIRBE, we reanalyzed the diffuse sky brightness at 1.25 and 2.2 μ {{m}}, which consists of zodiacal light, diffuse Galactic light (DGL), integrated starlight (ISL), and isotropic emission including the extragalactic background light. Our new analysis including an improved estimate of the DGL and the ISL with the 2MASS data showed that deviations of the isotropic emission from isotropy were less than 10% in the entire sky at high Galactic latitude (| b| \\gt 35^\\circ ). We derived the DGL to 100 μm brightness ratios of ˜4.79 and ˜1.49 n W m-2 MJy-1 at 1.25 and 2.2 μm, respectively. The result of our analysis revealed a significantly large isotropic component at 1.25 and 2.2 μ {{m}} with intensities of 60.15 ± 16.14 and 27.68+/- 6.21 {{n}} {{W}} {{{m}}}-2 {{sr}}-1, respectively. This intensity is larger than the integrated galaxy light, upper limits from γ-ray observation, and potential contribution from exotic sources (i.e., Population III stars, intrahalo light, direct collapse black holes, and dark stars). We therefore conclude that the excess light may originate from the local universe: the Milky Way and/or the solar system.

  5. Measurements of Diffuse Sky Emission Components in High Galactic Latitudes at 3.5 and 4.9 um Using Dirbe and WISE Data

    NASA Astrophysics Data System (ADS)

    Sano, K.; Kawara, K.; Matsuura, S.; Kataza, H.; Arai, T.; Matsuoka, Y.

    2016-02-01

    Using all-sky maps obtained from the Cosmic Background Explorer/Diffuse Infrared Background Experiment (DIRBE) at 3.5 and 4.9 μm, we present a reanalysis of diffuse sky emissions such as zodiacal light (ZL), diffuse Galactic light (DGL), integrated starlight (ISL), and isotropic residual emission including the extragalactic background light (EBL). Our new analysis, which includes an improved estimate of ISL using the Wide-field Infrared Survey Explorer data, enabled us to find the DGL signal in a direct linear correlation between diffuse near-infrared and 100 μm emission at high Galactic latitudes (| b| \\gt 35^\\circ ). At 3.5 μm, the high-latitude DGL result is comparable to the low-latitude value derived from the previous DIRBE analysis. In comparison with models of the DGL spectrum assuming a size distribution of dust grains composed of amorphous silicate, graphite, and polycyclic aromatic hydrocarbon (PAH), the measured DGL values at 3.5 and 4.9 μm constrain the mass fraction of PAH particles in the total dust species to be more than ˜2%. This was consistent with the results of Spitzer/IRAC toward the lower Galactic latitude regions. The derived residual emission of 8.9 ± 3.4 nWm-2 sr-1 at 3.5 μm is marginally consistent with the level of integrated galaxy light and the EBL constraints from the γ-ray observations. The residual emission at 4.9 μm is not significantly detected due to the large uncertainty in the ZL subtraction, the same as in previous studies. Combined with our reanalysis of the DIRBE data at 1.25 and 2.2 μm, the residual emission in the near-infrared exhibits the Rayleigh-Jeans spectrum.

  6. "O Ensaio como Forma" ou Um Ensaio acerca da Teoria Critica da Sociedade ("The Essay as Form" or An Essay about the Critical Theory of Society).

    ERIC Educational Resources Information Center

    Giordano, Rosely

    2000-01-01

    Illuminates the critical theory project, with themes permeating the theoretical constructions of Frankfurt (Germany). Debates the predominance of positivism in the production of knowledge. Speculates that "the essay as form" constitutes itself as a representation of the concept of the Enlightenment. Concludes with a dialogue between…

  7. VizieR Online Data Catalog: Library of Spectra (0.5 to 2.5um) of Cool Stars (Lancon+ 2000)

    NASA Astrophysics Data System (ADS)

    Lancon, A.; Wood, P. R.

    2000-07-01

    The present catalogue contains 182 low resolution optical spectra, 145 medium resolution (R~1100) near-IR spectra, and 112 merged optical+near-IR spectra that range from about 510 to 2450 nm. The observed stars are luminous cool objects: the sample includes red giants, red supergiants, oxygen rich and carbon rich long period variables (asymptotic giant branch stars), as well as a few Galactic Bulge and LMC/SMC stars. The optical data were acquired on the so-called 74 inch Telescope at Mount Stromlo Observatory. The near-IR data were acquired with the Cryogenic Array Spectrometer and Imager CASPIR on the 2.3 meter Australian National University Telescope at Siding Spring Observatory. Optical and near-IR data for variable objects have been merged only when both were taken less than 15 days apart; but both spectral ranges are also provided separately. The spectra are corrected for telluric absorption. However, in regions where the transmission of the Earth atmosphere is close to zero the fluxes recovered remain highly uncertain. The flux calibration is based on a series of reference stars, for which a theoretical intrinsic energy distribution was assumed. An absolute flux calibration (to about 10% accuracy) was only achieved in exceptional cases; in the other cases, the absolute fluxes can be off their real values by an order of magnitude due to slit losses (for the programme star and/or the reference star) and to non-photometric wheather. Uncertainties in the relative values of fluxes along each spectrum are described in the paper. (8 data files).

  8. The FLARE mission: deep and wide-field 1-5um imaging and spectroscopy for the early universe: a proposal for M5 cosmic vision call

    NASA Astrophysics Data System (ADS)

    Burgarella, D.; Levacher, P.; Vives, S.; Dohlen, K.; Pascal, S.

    2016-07-01

    FLARE (First Light And Reionization Explorer) is a space mission that will be submitted to ESA (M5 call). Its primary goal (~80% of lifetime) is to identify and study the universe before the end of the reionization at z > 6. A secondary objective (~20% of lifetime) is to survey star formation in the Milky Way. FLARE's strategy optimizes the science return: imaging and spectroscopic integral-field observations will be carried out simultaneously on two parallel focal planes and over very wide instantaneous fields of view. FLARE will help addressing two of ESA's Cosmic Vision themes: a) << How did the universe originate and what is it made of? » and b) « What are the conditions for planet formation and the emergence of life? >> and more specifically, << From gas and dust to stars and planets >>. FLARE will provide to the ESA community a leading position to statistically study the early universe after JWST's deep but pin-hole surveys. Moreover, the instrumental development of wide-field imaging and wide-field integral-field spectroscopy in space will be a major breakthrough after making them available on ground-based telescopes.

  9. A temperature-controlled cell for X-ray study of liquid systems using a commercial DRON-UM1 diffractometer

    SciTech Connect

    Petrun`kin, S.P.; Garavina, E.V.; Trostin, V.N.

    1995-02-01

    A container (cell) and a temperature-control system have been designed enabling one to carry out x-ray diffraction study of liquid samples both at a fixed temperature and within a certain temperature range using a commercial DRON-UMl x-ray diffractometer. Special features of the cell and the materials used for it allow one to study both chemically inert and corrosive liquids.

  10. [Inhibition of decomposing leaf litter of Cinnamomum camphora on growth of Capsicum annu- um and the alleviation effect of nitrogen application].

    PubMed

    Chen, Hong; Hu, Ting-xing; Wang, Qian; Hu, Hong-ling; Jiang, Xue; Zhou, Guang-liang; Chen, Gang

    2015-02-01

    Effects of decomposing leaf litter of Cinnamomum camphora on growth, physiological and phenological traits of Capsicum annuum, and modification of these effects by nitrogen application were investigated using a pot experiment. C. camphora leaf litter was applied at rate of 0, 25, 50 100 g per pot, resulting into four treatments, i.e., CK (the control), L25, L50, and L100. Nitrogen application was firstly performed on the 39th d of decomposition (3.0 g urea was added to each pot six times). Leaf area, plant height, basal diameter and biomass production of C. annuum were all inhibited sharply by exposure to the leaf litter, and the inhibition effect increased with the increasing leaf litter in terms of both the intensity and the stability. Treated with L25, budding number reduced by 88.7% averagely during 55th-75th d, and the rate of fructification plant decreased by 40% on the 96th d of decomposition, while neither buds nor fruits were observed when exposed to L50 and L100 at that time. Pigment contents and net photosynthetic rate (Pn) were impacted due to leaf litter addition, and malonaldehyde (MDA) was only markedly promoted by L100. Inhibition on growth and development of C. annuum caused by leaf litter decomposition could be alleviated by nitrogen application. Leaf area treated with leaf litter recovered to the control level on the 52nd d after nitrogen application, and similar results appeared on the 83rd d after nitrogen application for other growth traits. Budding and fructification status were also visibly improved.

  11. Tissue welding for corneal wound suture with a CW 1.9-um diode laser: an in-vivo preliminary study

    NASA Astrophysics Data System (ADS)

    Desmettre, Thomas; Mordon, Serge R.; Mitchell, Valerie A.

    1996-01-01

    This study aimed to evaluate the interest of a 1.9 micrometer diode laser for corneal wound suture. Six adult albino rabbits were anesthetized. A 7 mm corneal incision was practiced on the right eye. For 3 animals (laser plus stitch) the incision was surgically sutured with 2 stitches of a nylon monofilament and laser impacts were performed between the stitches. For 3 animals (laser only) juxtaposed lasers impacts were realized to suture the wound. After the procedure the animals were examined daily for signs of inflammation, infection and for healing of the corneal wound. Material was obtained for histological examination 1 month after the procedure. Approximation of the edges of the would was successfully obtained in the (laser plus stitch) group. In the (laser only) group this approximation remained troublesome. After the procedure, one cornea of the (laser only) group disclosed a little leakage during 2 days. Histological examination assessed the welding of the corneal wound in the two groups provided structural modifications and some inflammatory signs. Corneal welding using a 1.9 micrometer diode laser is possible either with laser and stitch or with laser only. The approximation of the edges of the wound with additional stitches is an evident drawback. The use of additional stitches should be avoided to keep the theoretical advantages of corneal would suture using laser welding.

  12. Heavy-ion broad-beam and microprobe studies of single-event upsets in 0.20 um SiGe heterojunction bipolar transistors and circuits.

    SciTech Connect

    Fritz, Karl; Irwin, Timothy J.; Niu, Guofu; Fodness, Bryan; Carts, Martin A.; Marshall, Paul W.; Reed, Robert A.; Gilbert, Barry; Randall, Barbara; Prairie, Jason; Riggs, Pam; Pickel, James C.; LaBel, Kenneth; Cressler, John D.; Krithivasan, Ramkumar; Dodd, Paul Emerson; Vizkelethy, Gyorgy

    2003-09-01

    Combining broad-beam circuit level single-event upset (SEU) response with heavy ion microprobe charge collection measurements on single silicon-germanium heterojunction bipolar transistors improves understanding of the charge collection mechanisms responsible for SEU response of digital SiGe HBT technology. This new understanding of the SEU mechanisms shows that the right rectangular parallele-piped model for the sensitive volume is not applicable to this technology. A new first-order physical model is proposed and calibrated with moderate success.

  13. Near-Infrared Continuum and 3.3um PAH Imaging of the Starburst Ring in the Type I Seyfert Galaxy NGC 7469

    NASA Technical Reports Server (NTRS)

    Mazzarella, J.; Voit, G.; Soifer, B.; Matthews, K.; Graham, J.; Armus, L.; Shupe, D.

    1993-01-01

    High resolution near-infrared images of the type 1 Seyfert Galaxy NGC 7469 have been obtained to probe its dusty nuclear environment. Direct images are relatively featureless, but residual images created by subtacting a smooth model based on best-fitting elliptical isoophotes reveal a tight inner spiral whose high surface-brightness portions correspond to a previously detected 3.

  14. Resist profile and CD control improvement by using optimized resist thickness and substrate film stack ratio for 0.35-um logic process

    NASA Astrophysics Data System (ADS)

    Fan, Ming H.; Yu, Raymond; Chu, Ronfu; Lim, Chet Ping

    1997-08-01

    LOCOS is the most widely used method for 0.35 micrometers process isolation. 2000 angstrom silicon nitride on 200 angstrom padoxide was selected as oxidation barrier before process optimization for the need of control the bird's beak and stress which affects the subsequent gate oxide quality. However, resist profile is prone to footing at this film stack. Severe footing could make minimum space CD too small, even not opened, to cause isolation failure. Experiment data shows that if nitride thickness varies from 1.9 K to 2.1 K, line CD variation can be up to 0.08 micrometers for a 0.6 micrometers line, which is about 80 percent of CD variation budget. Based on simulation results, 8 different nitride thickness in the range of 1750 angstrom to 2100 angstrom with step of 50 angstrom were deposited on 200 angstrom padoxide. Swing curve, CD versus nitride thickness for resist Emax and Emin, CD versus different exposure dose charts were obtained. Resist profile cross-sectional SEM pictures were also done to confirm simulation and in-line CD SEM measurement. An optimum combination of substrate film stack and resist thickness was selected. After implementation of this optimization, the sensitivity of CD to the nitride thickness was greatly reduced. Better resist profile and CD control were obtained. This was well confirmed by in-line monitoring data.

  15. Primary parapharyngeal and skull base synovial sarcoma in a 13-year-old boy with neurofibromatosis radiologically misdiagnosed as a benign lesion.

    PubMed

    Zahir, Shokouh Taghipour; Sharahjin, Naser Sefidrokh; Dadgarnia, Mohammad Hossein

    2013-06-03

    Synovial sarcoma is a rare form of malignant tumour and accounting approximately for 8% of all soft tissue sarcomas. Head and neck synovial sarcomas are uncommon and parapharyngeal space involvement is extremely rare. We report a case of synovial sarcoma in the parapharyngeal space of a 13-year-old boy with a history of neurofibromatosis presented with odynophagia, ptosis and left submandibular mass. The lesion extended from retrostyloid parapharyngeal space to the skull base and foramen jugular superiorly. The first clinical and radiological impressions were carotid jugular related tumours such as schwannoma and paraganglioma.

  16. Lemierre’s Syndrome presenting with neurological and pulmonary symptoms: Case report and review of the literature

    PubMed Central

    Aggarwal, Sushil Kumar; Nath, Alok; Singh, Rajni; Keshri, Amit

    2013-01-01

    Lemierre’s Syndrome (LS) is a potentially life-threatening condition, characterized by clinical or radiologic evidence of internal jugular vein thrombosis following an oropharyngeal infection, most commonly by Fusobacterium necrophorum. A high index of suspicion and early recognition is important for successful management and to prevent systemic complications like multiorgan failure with extremely high morbidity, prolonged hospitalization and, not uncommonly, death. We are reporting a rare case of LS that was complicated with internal jugular vein and cavernous sinus thrombosis along with lung metastatic lesions, which was diagnosed and treated at our institute. PMID:23956578

  17. Review of venous anatomy for venographic interpretation in chronic cerebrospinal venous insufficiency.

    PubMed

    Werner, John D; Siskin, Gary P; Mandato, Kenneth; Englander, Meridith; Herr, Allen

    2011-12-01

    Chronic cerebrospinal venous insufficiency (CCSVI) represents a recently described condition that may potentially contribute to the symptoms experienced by patients with multiple sclerosis. The evaluation of a prospective patient for CCSVI often involves an invasive evaluation with venography of the internal jugular and azygos veins. The purpose of this article is to review the normal anatomy of the internal jugular, vertebral, and azygos veins, as an understanding of these veins is necessary for appropriate interpretation of the venograms obtained to evaluate patients for CCSVI.

  18. Autogenous vein graft thrombosis following exposure to calcium-free solutions (calcium paradox).

    PubMed

    Nozick, J H; Farnsworth, P; Montefusco, C M; Parsonnet, V; Ruigrok, T J; Zimmerman, A N

    1981-01-01

    The morphological and functional effects of calcium-free and calcium-containing solutions on canine jugular vein intima were examined under conditions which closely resemble those techniques currently employed in peripheral vascular and aortocoronary bypass surgery. Veins that had been exposed only to calcium-containing solutions remained patent for the duration of the experimental period. Vein perfusion with a calcium-free solution, however, resulted in disruption of the jugular vein intima once calcium ions were reintroduced. Autogenous as a femoral arterial graft became thrombosed within 60 minutes. It is therefore suggested that vein grafts of autogenous origin be irrigated with calcium-containing solutions to prevent intimal damage and thrombosis.

  19. Phenotypic Heterogeneity by Germline Mismatch Repair Gene Defect in Lynch Syndrome Patients.

    PubMed

    Hernâni-Eusébio, Jorge; Barbosa, Elisabete

    2016-10-01

    Introdução: A síndrome de Lynch é a forma hereditária mais comum de cancro colo-rectal, sendo também responsável por cancro do endométrio e de outros tipos. Associa-se a mutações germinativas nos genes de mismatch repair do ADN e a instabilidade de microssatélites. As mutações MLH1 e MSH2 têm um fenótipo de síndrome de Lynch ‘clássico’, sendo o MSH2 mais associado a cancro extra-cólico. Mutações do MSH6 e PMS2 têm um fenótipo atípico. A expressão clínica é heterogénea, existindo uma correlação entre o gene mismatch repair mutado e o padrão fenotípico. Material e Métodos: Análise retrospetiva dos dados clínicos de doentes que cumpriam os critérios de Amesterdão ou que tinha mutações nos genes mismatch repair, entre setembro de 2012 e outubro de 2015. Resultados: Identificámos 28 doentes. Dezassete tinham cancro colo-rectal sendo a localização no cólon direito predominante. Cinco tiveram cancro do endométrio (mediana da idade de diagnóstico – 53), sem qualquer mutação no MSH6. Cinco desenvolveram outros cancros. Todos os casos com mutações mismatch repair estudados tinham instabilidade de microssatélites. Discussão: Na maioria dos casos foi encontrada mutação no MSH2 apesar de o MLH1 ser descrito na literatura como o gene mais frequentemente mutado. Interessa dizer que os doentes com cancro colo-rectal não evidenciam uma tendência para ter muito infiltrado inflamatório. Na maioria dos casos foi realizada colectomia parcial apesar da incidência elevada de lesões síncronas e metácronas associadas. Histerectomia e anexectomia profilática foi realizada em doentes em menopausa/perimenopausa. Conclusão: O registo standardizado dos dados dos doentes poderá levar a um melhor acompanhamento e conhecimento desta síndrome. O uso das Guidelines de Bethesda poderá identificar novos casos que escapam aos critérios de Amesterdão. A pesquisa de instabilidade de microssatélites deve ser feita em muito maior n

  20. 76 FR 67792 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-02

    ..., Mexico; Calle Antonio Caso No. 500, Colonia Aurora, Culiacan, Sinaloa, Mexico; Calle Amapola No. 12... AUTODROMO CULIACAN, Culiacan, Sinaloa, Mexico; Calle Antonio Caso No. 500, Colonia Aurora, Culiacan,...