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  1. Osaka and its technology, Number 3, 1983

    SciTech Connect

    Not Available

    1983-01-01

    The Osaka Municipal Urban Engineering Information Center was established in 1982 with the objective to collect, classify and exchange theses and technical information on urban engineering and technology. This issue contains the following articles: Urban Development Strategy for Osaka City; Construction of Abeno Station on the Tanimachi Line of Osaka Municipal Subway Using the Shield Method; Construction of Tennoji-Benten Trunk Sewer; SIL-B Process- A new Method for the Solidification Treatment of Sludge; Studies on Deodorization by Activated Sludge; Estimation of Long-Term Average Concentration of NO sub 2 in Areas Adjacent to Trunk Roads; Development of a Soil Waste Recycling Plant and its System; and Upright Wave-dissipation Caisoon-Type Breakwaters and Dikes.

  2. Spring time photochemical air pollution in Osaka

    SciTech Connect

    Wakamatsu, Shinji; Uno, Itsushi; Ohara, Toshimasa

    1996-12-31

    High concentrations of nitrogen dioxide are frequently observed in Osaka area in spring season. To clarify this, a series of three dimensional field observation was conducted in April 1993 covering Osaka and surrounding area. Vertical and horizontal distributions of ozone, NO, NO{sub x}, SO{sub 2}, CO, aerosol species, hydrocarbon species and meteorological parameter such as temperature, uv radiation, wind speed, wind direction are measured on the ground and aloft. Covering the observational period yellow sand transportation from the continent and stratospheric ozone intrusion were also observed under the meteorological condition of moving high pressure system. During the aircraft observation of 19 to 21 April 1993 high concentration of photochemical air pollution was observed aloft over Osaka area. Maximum ozone concentration was me than 150 ppb. Vertical distribution of ozone showed uniform profile up to 2500m in day time. At Mt. Ikoma (600 m) ozone concentration had been almost constant ranging 80-100 ppb throughout the observational period. To clarify this phenomena three dimensional photochemical air pollution simulation model was applied based on the real meteorological and emission conditions. Simulated result showed photochemical reaction play an important role to form the spring time high concentrations of nitrogen dioxide in Osaka.

  3. Nuclear physics frontier at RCNP, Osaka University

    SciTech Connect

    Ong, H. J.

    2014-03-05

    Cyclotron accelerator facility and research activities at Research Center for Nuclear Physics (RCNP), Osaka University, are presented. A special focus is given on several topics in nuclear physics where interesting and important experiment results relevant to the nuclear structure as well as the nuclear astrophysics have been reported.

  4. Nuclear physics frontier at RCNP, Osaka University

    NASA Astrophysics Data System (ADS)

    Ong, H. J.

    2014-03-01

    Cyclotron accelerator facility and research activities at Research Center for Nuclear Physics (RCNP), Osaka University, are presented. A special focus is given on several topics in nuclear physics where interesting and important experiment results relevant to the nuclear structure as well as the nuclear astrophysics have been reported.

  5. Development of Osaka gas type planar SOFC

    SciTech Connect

    Iha, M.; Shiratori, A.; Chikagawa, O.

    1996-12-31

    Osaka Gas Co. has been developing a planar type SOFC (OG type SOFC) which has a suitable structure for stacking. Murata Mfg. Co. has begun to develop the OG type SOFC stack through joint program since 1993. Figure 1 shows OG type cell structure. Because each cell is sustained by cell holders acting air manifold, the load of upper cell is not put on the lower cells. Single cell is composed of 3-layered membrane and LaCrO{sub 3} separator. 5 single cells are mounted on the cell holder, connected with Ni felt electrically, and bonded by glassy material sealant. We call the 5-cell stack a unit. Stacking 13 units, we succeeded 870 W generation in 1993. But the power density was low, 0.11 Wcm{sup -2} because of crack in the electrolyte and gas leakage at some cells.

  6. Development of the Department of Ophthalmology at Osaka University.

    PubMed

    Oie, Yoshinori; Kamei, Motohiro; Maeda, Naoyuki; Fujikado, Takashi; Nishida, Kohji

    2013-01-01

    Osaka University is one of the largest national universities and the sixth oldest university in Japan. Its academic roots extend to Tekijuku and Kaitokudo in the Edo period. Osaka University has the motto, "Live Locally, Grow Globally." This means that they work for their own local community and also work worldwide at the same time.The Osaka University Graduate School of Medicine is famous for basic research in immunology, including research on interleukin 6 and innate immunity, and translational research for regenerative medicine. Osaka University Hospital has 31 clinical departments and 2159 staff members, including 834 physicians. It serves 2515 outpatients and 940 inpatients per day. Approximately 8500 surgeries are performed every year. The Department of Ophthalmology at Osaka University is one of the largest ophthalmology departments in Japan. It has 24 faculty members, 9 graduate school students, and 9 residents. It has had 9 professors throughout its history. Their department has also produced active professors in the wide field of ophthalmology.Their department is known for a large amount of high clinical activity. Their advanced clinical practice performs translational research on the regenerative medicine of the cornea, artificial retina, diagnostic instruments and tools, apoptosis of photoreceptors, and drug discovery. Many ophthalmologists and staff members have contributed to the development of the Department of Ophthalmology at Osaka University.

  7. Stability of Osaka Mutant and Wild-Type Fibril Models.

    PubMed

    Berhanu, Workalemahu M; Alred, Erik J; Hansmann, Ulrich H E

    2015-10-15

    Single amino acid mutations in amyloid-beta (Aβ) peptides can lead to early onset and increased severity of Alzheimer's disease. An example is the Osaka mutation (Aβ1-40E22D), which is more toxic than wild-type Aβ1-40. This mutant quickly forms early stage fibrils, one of the hallmarks of the disease, and these fibrils can even seed fibrilization of wild-type monomers. Using molecular dynamic simulations, we show that because of formation of various intra- and intermolecular salt bridges the Osaka mutant fibrils are more stable than wild-type fibrils. The mutant fibril also has a wider water channel with increased water flow than the wild type. These two observations can explain the higher toxicity and aggregation rate of the Osaka mutant over the wild type.

  8. Descriptive epidemiology of bile duct carcinoma in Osaka.

    PubMed

    Ikeda, Akiko; Miyashiro, Isao; Nakayama, Tomio; Ioka, Akiko; Tabuchi, Takahiro; Ito, Yuri; Tsukuma, Hideaki

    2013-11-01

    An outbreak of bile duct carcinoma has been reported among workers in a certain printing company in Osaka, Japan, where there was no descriptive epidemiological study. We conducted descriptive studies of bile duct carcinoma in Osaka. Based on the data from the Osaka Cancer Registry, the incidence and survival rate of intrahepatic and extrahepatic bile duct carcinomas, gallbladder carcinomas and hepatocellular carcinomas were analyzed. The study period was between 1975 and 2007, and total 108 407 incidents were retrieved from the Osaka Cancer Registry. Age- and sex-specific incidence rates and age-standardized incidence rates were calculated. Standardized incidence ratios were evaluated for each municipality in Osaka prefecture. Relative 5-year survival rates were also calculated for the cases diagnosed between 1993 and 2005. Age-standardized incidence rates of bile duct carcinomas increased distinctly from the middle of the 1970s to the early 1980s in males and the 1990s in females. However, no distinct increase in the incidence rates was observed in 2000. Standardized incidence ratios of those did not exceed the unity significantly in males between 1992 and 2007. In females, standardized incidence ratios exceeded the unity significantly in a few regions without any relation to the location of the printing company where the outbreak was reported. The relative 5-year survival rate is generally poor; however, patients who were diagnosed with localized disease at the age of 25-49 years showed a better survival. Neither change in trend nor regional accumulation of bile duct carcinoma was confirmed in Osaka, corresponding to the outbreak reported in the printing company.

  9. Characterization of bottom sediments from Osaka Bay, Japan

    NASA Astrophysics Data System (ADS)

    Tokunaga, S.; Hoshika, A.; Tatsumoto, H.

    1995-06-01

    The physical, chemical, and dewatering characteristics of 19 bottom sediments from Osaka Bay, Japan, have been analyzed to aid in the development of sediments in the coastal bay area. The sediments in the east near Osaka Port were highly polluted from the influence of human activities and were difficult to dewater. These sediments were composed of fine particles, low in pH, zetapotential, and initial settling rate, and were high in ignition loss, metal concentrations, compression volume, specific resistance, cake water content, and drying index. However, the sediments near Akashi Channel showed the reverse where they are affected by strong tidal current. A correlation analysis has been made of all the parameters. There are significant relationships between all the dewatering parameters. Therefore, sediments difficult to dewater by gravity settling are also difficult to dewater by vacuum filtration and solar evaporation. Sediments containing fine particles and pollutants are difficult to dewater. Several forms of pollutants can occur in the sediments.

  10. Technology assessment of PACS in Osaka University Hospital.

    PubMed

    Inamura, K; Satoh, K; Kondoh, H; Mori, Y; Kozuka, T

    1994-05-01

    This paper describes a methodology of PACS technology assessment and gives examples of the results of measurement of 24 items of PACS-related situations of image diagnosis systems in Osaka University Hospital before a PACS is installed. These data are to be compared with the data which will be measured after PACS is installed in the new Osaka University Hospital, in order to complete our technology assessment. We propose common variables, units, and conditions of measurement, in order to establish a standard method of data comparison between before and after PACS installation in hospitals at large. We designed our PACS taking technology assessment into account. We do not stop the technology assessment at the efficacy evaluation, because PACS must be more than a tool for radiological practice. We extend the technology assessment into the effectiveness evaluation, so that PACS is a part of radiological practice itself, and diagnostic accuracy, economy and efficiency are the results of PACS operation.

  11. Novel bladder preservation therapy with Osaka Medical College regimen.

    PubMed

    Azuma, Haruhito; Inamoto, Teruo; Takahara, Kiyoshi; Nomi, Hayahito; Hirano, Hajime; Ibuki, Naokazu; Uehara, Hiroshi; Komura, Kazumasa; Minami, Koichiro; Uchimoto, Taizo; Saito, Kenkichi; Takai, Tomoaki; Tanda, Naoki; Yamamoto, Kazuhiro; Narumi, Yoshihumi; Kiyama, Satoshi

    2015-02-01

    We investigated the effect of balloon occluded arterial infusion of an anticancer agent (cisplatin/gemcitabine), used concomitantly with hemodialysis, which delivers an extremely high concentration of anticancer agent to the tumor site without systemic adverse effects, along with concurrent radiation (referred to as the Osaka Medical College regimen) in patients with advanced bladder cancer. A total of 329 patients (TisN0 16, T2N0 174, T3N0 77, T4N0 22 and TxN+ 40) were assigned to receive the Osaka Medical College regimen. Patients who did not achieve complete response underwent total cystectomy or secondary balloon occluded arterial infusion with an increased amount of cisplatin and/or gemcitabine. The Osaka Medical College regimen allowed 83.6% (276 of 329) of patients in total and 93.6% (250 of 267) of patients with organ confined disease (including T3b) to achieve complete response. Of the patients with a complete response 96% (240 of 250) survived with a functional bladder without evidence of recurrent disease within a mean followup of 159 weeks. Although lymph node involvement, especially N2 stage, was selected as a significant risk factor for treatment failure and survival, it was noteworthy that 61.9% of patients with N1 disease achieved complete response and that the 5-year overall survival rate was 72.2%. No patients had grade III or more severe toxicities. The Osaka Medical College regimen, a new bladder preservation strategy, can be curative not only in patients for whom cystectomy is indicated, but also in patients whose condition is not amenable to curative treatment because of disease stage, age or other factors, and for whom merely palliative therapy would otherwise seem the only option. Copyright © 2015 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.

  12. Waveform simulation of predominant periods in Osaka basin

    NASA Astrophysics Data System (ADS)

    Petukhin, A.; Tsurugi, M.

    2016-12-01

    Predominant period of strong ground motions is an important parameter in earthquake engineering practice. Resonance at predominant period may result in collapse of building. Usually, predominant periods are associated with the soil resonances. However, considering that strong ground motions are composed from source, path and site effects, predominant periods are affected by source and propagation path too. From another side, 3D basin interferences may amplify quite different periods, depending on site location relatively to the basin edges and independently on the soil depth. Moreover, constructive or destructive interference of waves from different asperities of a large source may enhance or diminish amplitudes at a particular predominant period respectively. In this study, to demonstrate variations of predominant periods due to complicated effects above, we simulated wavefield snapshots and waveforms at a few representative sites of Osaka basin, Japan. Seismic source is located in Nankai trough, hosting anticipated M9 earthquake. 3D velocity structure is combined from JIVSM velocity structure (Koketsu et al., 2012) and Osaka basin structure of Iwaki and Iwata, 2011. 3D-FDM method is used to simulate waveforms. Simulation results confirm some previous results that due to elongated elliptical shape of Osaka basin, interference effects are strong and peak amplitudes has characteristic stripped pattern elongated in parallel to the long axis of basin. We demonstrate that predominant periods have similar pattern and value of predominant period may strongly depend on the location of site and azimuthal orientation of waveform component.

  13. Trend analysis of surgery revenues at Osaka University Hospital.

    PubMed

    Jitsukawa, S

    1984-01-01

    To identify medical and administrative revenue trends at a surgical center, for use in strategic planning, an off-line data processing system utilizing coding sheets was developed. Data on 66,402 surgical procedures performed at the Osaka University Hospital Surgical Center between 1966 and 1981 were processed to study trends in revenues. Trend analysis shows that (a) revenues at the surgical center have been increasing year by year; (b) technical charges, such as operation and anesthesia fees, have increased with each revision of the medical remuneration system of Japanese government health insurance; and (c) the length of time patients stay in the operating room has gradually increased.

  14. Surveillance of adenovirus respiratory infections in children in Osaka, Japan.

    PubMed

    Hiroi, Satoshi; Morikawa, Saeko; Nakata, Keiko; Kase, Tetsuo

    2017-09-11

    Human adenovirus (HAdV) strains isolated from respiratory specimens of 139 children between 2008 and 2015 were analyzed with the intent of evaluating the endemic situation of HAdV infections in Osaka, Japan. The cases increased in spring and winter, and the infections were confirmed mainly in children aged ≤ 5 years, comprising 91.9% of the total population examined. Molecular typing of the isolates revealed that the most common types belonged to HAdV-B and HAdV-C, and a case of co-infection with HAdV-C1 and HAdV-C2 was confirmed. The median age of HAdV-E cases were higher than that of HAdV-B and -C cases. These results revealed age and seasonal distribution of respiratory infections caused by HAdVs in children in Osaka, and indicate that the majority of children might have acquired immunity through infection with endemic HAdVs before school age.

  15. [Explicit and implicit attitudes toward standard-Japanese and Osaka-dialect language use].

    PubMed

    Watanabe, Takumi; Karasawa, Kaori

    2013-04-01

    This article examines the effects of language use on explicit and implicit attitudes. We employed the matched-guise technique to measure participants' impressions of standard-Japanese and Osaka-dialect speakers. Implicit attitudes were assessed by the Implicit Association Test (IAT). The Osaka-dialect speaker was evaluated as warmer than the standard-Japanese speaker, suggesting that explicit attitudes toward the Osaka dialect have changed positively. On the other hand, the results for the impression of intelligence were consistent with the previous literature that the standard-Japanese speaker was seen as more intelligent than the Osaka-dialect speaker. Compared with explicit attitudes, the analyses of implicit attitudes revealed that participants showed a consistent implicit bias favoring standard-Japanese language use. The changing processes and relationships of explicit and implicit attitudes were discussed.

  16. The management for tuberculosis control in Greater London in comparison with that in Osaka City: lessons for improvement of TB control management in Osaka City urban setting.

    PubMed

    Ohkado, Akihiro; Williams, Gini; Ishikawa, Nobukatsu; Shimouchi, Akira; Simon, Carter

    2005-07-01

    The tuberculosis (TB) notification in Osaka City has been persistently high compared with other urban areas in Japan. Although the TB notification in Greater London has kept much lower level compared with that in Osaka City, it has been also persistently high compared with other urban areas in the UK. Nonetheless, the contexts of the two cities relating TB control programme as well as the epidemiological situation greatly vary; there must be some lessons to be learnt from each other to improve each TB control programme to tackle against TB more effectively. Comparing the epidemiological situation of TB in both cities, it is obvious that Osaka City suffers TB more than Greater London in terms of the TB notification rate. Concerning the context of the TB control programme, Osaka City has centralised approach with strong local government commitment; Greater London, on the other hand, has an approach that is greatly fragmented but coordinated through voluntary TB Networks. This paper aims to draw some constructive and practical lessons from Greater London TB control management for further improvement of Osaka City TB control management through literature review and interview to health professionals. TB epidemiology in Greater London shows distinct features in the extent of TB in new entrants and TB co-infected with HIV in comparison with those in Osaka City. TB epidemiology in Osaka City is to a great extent specifically related to homeless people whereas in Greater London, this relationship occurs to a lesser extent. Both areas have relatively high TB-notification rates compared with national figures, and they have "TB hot spots" where remarkably high TB-notification rates exist. TB control in Greater London is characterised with decentralised and devolved services to local government health authorities supplemented with co-ordinating bodies across sectors as well as across Greater London. Sector-wide TB Network as well as London TB Group (LTBG) and London TB Nurses

  17. Long-period Ground Motion Simulation in the Osaka Basin during the 2011 Great Tohoku Earthquake

    NASA Astrophysics Data System (ADS)

    Iwata, T.; Kubo, H.; Asano, K.; Sato, K.; Aoi, S.

    2014-12-01

    Large amplitude long-period ground motions (1-10s) with long duration were observed in the Osaka sedimentary basin during the 2011 Tohoku earthquake (Mw9.0) and its aftershock (Ibaraki-Oki, Mw7.7), which is about 600 km away from the source regions. Sato et al. (2013) analyzed strong ground motion records from the source region to the Osaka basin and showed the following characteristics. (1) In the period range of 1 to 10s, the amplitude of horizontal components of the ground motion at the site-specific period is amplified in the Osaka basin sites. The predominant period is about 7s in the bay area where the largest pSv were observed. (2) The velocity Fourier amplitude spectra with their predominant period of around 7s are observed at the bedrock sites surrounding the Osaka basin. Those characteristics were observed during both of the mainshock and the largest aftershock. Therefore, large long-period ground motions in the Osaka basin are generated by the combination of propagation-path and basin effects. They simulated ground motions due to the largest aftershock as a simple point source model using three-dimensional FDM (GMS; Aoi and Fujiwara, 1999). They used a three-dimensional velocity structure based on the Japan Integrated Velocity Structure Model (JIVSM, Koketsu et al., 2012), with the minimum effective period of the computation of 3s. Their simulation result reproduced the observation characteristics well and it validates the applicability of the JIVSM for the long period ground motion simulation. In this study, we try to simulate long-period ground motions during the mainshock. The source model we used for the simulation is based on the SMGA model obtained by Asano and Iwata (2012). We succeed to simulate long-period ground motion propagation from Kanto area to the Osaka basin fairly well. The long-period ground motion simulations with the several Osaka basin velocity structure models are done for improving the model applicability. We used strong motion

  18. Draft Genome Sequence of Clostridium botulinum Type B Strain Osaka05, Isolated from an Infant Patient with Botulism in Japan

    PubMed Central

    Hosomi, Koji; Uchiyama, Jumpei; Ogura, Yoshitoshi; Umeda, Kaoru; Sakaguchi, Masakiyo; Kohda, Tomoko; Mukamoto, Masafumi; Misawa, Naoaki; Matsuzaki, Shigenobu; Hayashi, Tetsuya; Kozaki, Shunji

    2014-01-01

    Clostridium botulinum strain Osaka05, which has been isolated from an infant patient with botulism in Japan, is the first strain producing botulinum neurotoxin subtype B6. Here, we report the draft genome sequence of C. botulinum Osaka05. PMID:24459252

  19. Distribution of perfluoroalkyl compounds in Osaka Bay and coastal waters of Western Japan.

    PubMed

    Beškoski, Vladimir P; Yamamoto, Katsuya; Yamamoto, Atsushi; Okamura, Hideo; Hayashi, Mitsuru; Nakano, Takeshi; Matsumura, Chisato; Fukushi, Keiichi; Wada, Shinpei; Inui, Hideyuki

    2017-03-01

    Perfluoroalkyl acids (PFAAs) including perfluoroalkyl sulfonates (PFSAs) and perfluoroalkyl carboxylates (PFCAs) were analyzed in sediment samples taken from Ajifu Waterway in Osaka city, from Osaka Bay, and from Kagoshima Bay, as well as in fifteen seawater samples collected from Osaka Bay and coastal waters of Western Japan. In all sediment samples, only PFCAs were detected, and the highest concentration was determined in Ajifu Waterway, where ΣPFAA was 58990 ng kg(-1) dry weight. The total concentrations of PFAAs in sea water samples ranged between the limit of quantification and 53.4 ng L(-1), and perfluorohexanoic acid was the most prevalent and had the highest concentration of 37 ng L(-1). The changes in the patterns and concentrations of PFAAs in Osaka Bay and coastal waters of Western Japan indicate that the PFAAs in surface waters are influenced by sources from Keihanshin Metropolitan Area, mainly the Yodo River basin, and the dilution effect which naturally occurs during their transport to the Pacific Ocean.

  20. The Role and Challenges of School Social Work: An Examination from Practice in Osaka

    ERIC Educational Resources Information Center

    Yamano, Noriko

    2011-01-01

    This article describes the development of school social work in the Osaka Prefecture of Japan. The article focuses on micro, mezzo, and macro levels of school social work and documents the growth and development of school social work since 2005. (Contains 3 tables and 2 figures.)

  1. The Role and Challenges of School Social Work: An Examination from Practice in Osaka

    ERIC Educational Resources Information Center

    Yamano, Noriko

    2011-01-01

    This article describes the development of school social work in the Osaka Prefecture of Japan. The article focuses on micro, mezzo, and macro levels of school social work and documents the growth and development of school social work since 2005. (Contains 3 tables and 2 figures.)

  2. Light-Quark Baryon Spectroscopy from ANL-Osaka Dynamical Coupled-Channels Analysis

    NASA Astrophysics Data System (ADS)

    Kamano, Hiroyuki

    We review our recent efforts for determining resonance parameters associated with light-quark baryons (N*,Δ *,Λ *,Σ *) through comprehensive analyses of various meson production reactions off the nucleon within the ANL-Osaka dynamical coupled-channels approach.

  3. The Preliminary Development of a Vocabulary List for Osaka Jogakuin Junior College's First Year English Program.

    ERIC Educational Resources Information Center

    Cornwell, Steve; Kakutani, Tomoko

    1998-01-01

    A project to develop word lists for first-year English as a second language instruction at Osaka Jogakuin Junior College (Japan) is described. The lists were drawn from high-frequency vocabulary lists, with word selection based on course unit themes and rhetorical patterns. These include: introduction/people and places; women's issues;…

  4. DRAGON-Osaka experiment with local pollutants and long-range transported Asian aerosols

    NASA Astrophysics Data System (ADS)

    Nakata, M.; Mukai, S.; Sano, I.; Nakaguchi, Y.; Holben, B. N.; Sugimoto, N.

    2012-11-01

    It is known that local spatially and temporally resolved measurements of atmospheric aerosols in Asian urban city are meaningful since the aerosol distribution in East-Asia is complicated due to the increasing emissions of anthropogenic aerosols in association with economic growth and natural dust significantly varies with the seasons. In this work, we intend to show the spatial and temporal variation of atmospheric aerosols in East Asia, especially around AERONET/Osaka site and Dragon-Asia period, named "DRAGON-Osaka". AERONET (Aerosol Robotics Network) Osaka site was established in 2002 in the campus of Kinki University. Nowadays, LIDAR, PM2.5 / 10 measurements and others are available. The site data are useful for algorithm development of aerosol retrieval over busy city. However, human activities in this region also emit the huge amount of pollutions, thus it is needed to investigate the local distribution of aerosols in this region. In March 2012, to obtain maximum efficiency of DRAGON-Osaka, several Cimels are deployed at more sites as soon as possible. In order to investigate change of aerosol properties, PM-individual analysis is made with scanning electron microscope (SEM) coupled with energy dispersive X-ray analyzer (EDX). A componential analysis presents temporal variation of aerosol properties.

  5. Benthic foraminiferal assemblages in Osaka Bay, southwestern Japan: Faunal changes over the last 50 years

    USGS Publications Warehouse

    Tsujimoto, Akira; Nomura, Ritsuo; Yasuhara, Moriaki; Yoshikawa, Shusaku

    2006-01-01

    Live benthic foraminiferal assemblages from surface sediment in Osaka Bay collected in 1999 were analyzed to characterize the distribution of the modern foraminiferal assemblages. Foraminiferal assemblages were compared with those of previous studies to document environmental changes in Osaka Bay over the past 50 years. Sixty-one species of foraminifera belonging to 37 genera were recognized from the 1999 surface sediment samples. An agglutinated assemblage containing Trochammina hadai and Eggerella advena is dominant in the inner part of the bay and is related to eutrophication. The foraminiferal assemblage in areas deeper than about 20 m is composed of Eggerella advena, Ammonia beccarii forma A, and Pseudorotalia gaimardii. This assemblage may be influenced by the large clockwise Okinose Circulation Current which extends throughout the western bay. Foraminiferal assemblages in Osaka Bay have changed dramatically during the last 50 years. The Trochammina hadai-Eggerella advena assemblage became established in the inner part of the bay, reflecting eutrophication that progressed from the 1960s through the 1970s. This assemblage became dominant in 1983, and typically dominated the inner part of the bay. From 1983 to 1999, however, the abundance of taxa belonging to this assemblage decreased greatly following implementation of 1973 Osaka City bylaws that restricted wastewater discharge. Changes in benthic assemblages such as the decrease of Ammonia beccarii forma A and increase of Eggerella advena have occurred in response to decreased incidence of red tides, and floral change in the species that cause these tides. The results of this study demonstrate that the abundance and distribution of benthic foraminifers in Osaka Bay are intimately related to environmental changes related to the urbanization of coastal areas. ?? by the Palaeontological Society of Japan.

  6. Prevalence and Risk Factors for Self-Reported Violence of Osaka and Seattle Male Youths

    PubMed Central

    Bui, Laura; Farrington, David P.; Ueda, Mitsuaki; Hill, Karl G.

    2013-01-01

    Traditionally, Japan has been regarded as a country with low crime. Comparative research has given insights into the extent of similarities and differences in crime between America and Japan. The importance of these studies is the examination of whether Western-established criminological knowledge is applicable to non- Western societies like Japan. Unfortunately, comparative self-report studies involving Japan and investigating youth offending are scarce. The current study investigates risk factors and self-reports of violence from Osaka and Seattle male youths. The findings reveal that Japanese male youths self-report a higher prevalence of violence than Seattle male youths. Risk factors for violence, issues of comparability, and prevalence versus strength of relationships of risk factors are examined. It is concluded that the higher prevalence of violence in Osaka is primarily a function of the higher prevalence of troubled peers and risk taking. The findings call for replication of this type of comparative research. PMID:24013769

  7. Distributions of polycyclic aromatic hydrocarbons and alkylated polycyclic aromatic hydrocarbons in Osaka Bay, Japan.

    PubMed

    Miki, Shizuho; Uno, Seiichi; Ito, Kazuki; Koyama, Jiro; Tanaka, Hiroyuki

    2014-08-30

    Contaminations in sediments by polycyclic aromatic hydrocarbons (PAHs) and alkylated PAHs were investigated at 44 sites in Osaka Bay, Japan. Concentrations of total PAHs and alkylated PAHs were in the range 6.40-7800 ng/g dry weights and 13.7-1700 ng/g dry weights, respectively. The PAH concentrations tended to be higher along the shoreline in the vicinities of big ports, industrialized areas, and densely populated regions such as the cities of Osaka and Kobe. The major sources appeared to be pyrogenic or both pyrogenic and petrogenic at most of the sites. PAH concentrations were remarkably high at a site near Kobe, where the concentrations of dibenzo(a,h)anthracene and benzo(g,h,i)perylene exceeded the effects-range-medium concentration and eight PAHs were above the corresponding effects-range-low concentrations. Those PAHs may have been derived from the great fire associated with the large earthquake in 1995.

  8. A Coprological Survey of Intestinal Helminthes in Stray Dogs Captured in Osaka Prefecture, Japan

    PubMed Central

    KIMURA, Akio; MORISHIMA, Yasuyuki; NAGAHAMA, Shinya; HORIKOSHI, Takashi; EDAGAWA, Akiko; KAWABUCHI-KURATA, Takako; SUGIYAMA, Hiromu; YAMASAKI, Hiroshi

    2013-01-01

    ABSTRACT This study aimed to investigate intestinal helminth infection in stray dogs in Osaka Prefecture by surveying coprological samples from dogs captured from 2006–2011. Of 212 fecal samples collected, overall prevalence of infection was 39.2%. The most common species was Toxocara canis (25.0%), followed by Trichuris vulpis (8.0%), Spirometra erinaceieuropaei (3.3%), Taeniidae (2.4%), Ancylostoma caninum (1.9%) and Toxascaris leonine (0.5%). In the molecular analysis, all of the taeniid eggs were negative for Echinococcus multilocularis and were identified as other taeniid species (e.g., Taenia pisiformis). Our results suggest that stray dogs remain important infection reservoirs of zoonotic parasites in Osaka Prefecture. Therefore, control of stray dogs is crucial for reducing the risk of public health problems due to parasitic infections. PMID:23774027

  9. Highlighting the history of Japanese radio astronomy. 4: early solar research in Osaka

    NASA Astrophysics Data System (ADS)

    Orchiston, Wayne; Nakamura, Tsuko; Ishiguro, Masato

    2016-12-01

    For about two years, from late 1949, Minoru Oda and Tatsuo Takakura carried out solar observations from Osaka, initially with a hand-made horn and later with a small parabolic antenna connected to a 3.3 GHz receiver, but they only published one short paper on this work. At about the same time, Ojio and others at Osaka City University presented the concept of a solar grating array at a meeting of the Japan Physical Society, but this was never built. In this paper, we provide brief biographical accounts of Oda and Takakura before examining their radio telescopes and the observations that they made. We also briefly discuss the proposed Japanese solar grating array.

  10. Status report and biomedical applications of the institute of FEL, Osaka University

    NASA Astrophysics Data System (ADS)

    Awazu, Kunio; Asakawa, Makoto; Horiike, Hiroshi

    2003-07-01

    The Institute of Free-Electron Laser (iFEL) was established in April 2000 at Osaka University. The facility was constructed by the Free-Electron Laser Institute corporation (FELI) from 1992 to 1997. FELI demonstrated lasing in the spectral range from 0.28 to 20 μm. Efforts are still being made by Osaka University in order to extend the lasing range. In the operational period from April 2001 to March 2002, mid-infrared light of 5-20 μm was supplied for over 40 cooperative research programs on fields of semiconductor, bio-medical and environmental chemistry. An effort is ongoing to improve the property of the light. In this paper, the status of iFEL and some biomedical applications research are described.

  11. Prediction of long-period ground motions from huge subduction earthquakes in Osaka, Japan

    NASA Astrophysics Data System (ADS)

    Kawabe, H.; Kamae, K.

    2008-04-01

    There is a high possibility of reoccurrence of the Tonankai and Nankai earthquakes along the Nankai Trough in Japan. It is very important to predict the long-period ground motions from the next Tonankai and Nankai earthquakes with moment magnitudes of 8.1 and 8.4, respectively, to mitigate their disastrous effects. In this study, long-period (>2.5 s) ground motions were predicted using an earthquake scenario proposed by the Headquarters for Earthquake Research Promotion in Japan. The calculations were performed using a fourth-order finite difference method with a variable spacing staggered-grid in the frequency range 0.05 0.4 Hz. The attenuation characteristics ( Q) in the finite difference simulations were assumed to be proportional to frequency ( f) and S-wave velocity ( V s) represented by Q = f · V s / 2. Such optimum attenuation characteristic for the sedimentary layers in the Osaka basin was obtained empirically by comparing the observed motions during the actual M5.5 event with the modeling results. We used the velocity structure model of the Osaka basin consisting of three sedimentary layers on bedrock. The characteristics of the predicted long-period ground motions from the next Tonankai and Nankai earthquakes depend significantly on the complex thickness distribution of the sediments inside the basin. The duration of the predicted long-period ground motions in the city of Osaka is more than 4 min, and the largest peak ground velocities (PGVs) exceed 80 cm/s. The predominant period is 5 to 6 s. These preliminary results indicate the possibility of earthquake damage because of future subduction earthquakes in large-scale constructions such as tall buildings, long-span bridges, and oil storage tanks in the Osaka area.

  12. Light-Quark Baryon Spectroscopy within ANL-Osaka Dynamical Coupled-Channels Approach

    NASA Astrophysics Data System (ADS)

    Kamano, Hiroyuki

    2016-10-01

    Recent results on the study of light-quark baryons with the ANL-Osaka dynamical coupled-channels (DCC) approach are presented, which contain the N^* and Δ ^* spectroscopy via the analysis of π N and γ N reactions and the Λ ^* and Σ ^* spectroscopy via the analysis of K^- p reactions. A recent application of our DCC approach to neutrino-nucleon reactions in the resonance region is also presented.

  13. Explaining extreme ground motion in Osaka basin during the 2011 Tohoku earthquake

    NASA Astrophysics Data System (ADS)

    Tsai, Victor C.; Bowden, Daniel C.; Kanamori, Hiroo

    2017-07-01

    Despite being 770 km away from the epicenter, observed ground motions due to the Tohoku earthquake in the Osaka Basin were unexpectedly large, with an amplification of more than a factor of 20 compared to immediately outside the basin, and including 2.7 m peak-to-peak roof displacements at one high-rise building. The local ground motions exceeded expectations based on standard computations of site response by a factor of 3, predicted frequencies of peak acceleration were off by at least 50%, and such discrepancies have not yet been explained quantitatively. Here we show that utilizing semianalytic theory for surface-wave amplification, we are able to accurately predict both the amplitudes and frequencies of large ground amplification in the Osaka Basin using only knowledge of the local one-dimensional structure. Comparison between this simple prediction and observed amplification was not expected to be so favorable and suggests that simple one-dimensional surface-wave site amplification factors can be useful in the absence of full three-dimensional wave propagation simulations. Such surface-wave amplification factors can be included in addition to the standard measures of site-specific site amplification and should help explain strong ground motion variability in future large earthquakes that shake Osaka Basin and elsewhere in the world.

  14. Anthropogenic effects on the subsurface thermal and groundwater environments in Osaka, Japan and Bangkok, Thailand.

    PubMed

    Taniguchi, Makoto; Shimada, Jun; Fukuda, Yoichi; Yamano, Makoto; Onodera, Shin-ichi; Kaneko, Shinji; Yoshikoshi, Akihisa

    2009-04-15

    Anthropogenic effects in both Osaka and Bangkok were evaluated to compare the relationships between subsurface environment and the development stage of both cities. Subsurface thermal anomalies due to heat island effects were found in both cities. The Surface Warming Index (SWI), the departure depth from the steady geothermal gradient, was used as an indicator of the heat island effect. SWI increases (deeper) with the magnitude of heat island effect and the elapsed time starting from the surface warming. Distributions of subsurface thermal anomalies due to the heat island effect agreed well with the distribution of changes in air temperature due to the same process, which is described by the distribution of population density in both Osaka and Bangkok. Different time lags between groundwater depression and subsidence in the two cities was found. This is attributed to differences in hydrogeologic characters, such as porosity and hydraulic conductivity. We find that differences in subsurface degradations in Osaka and Bangkok, including subsurface thermal anomalies, groundwater depression, and land subsidence, depends on the difference of the development stage of urbanization and hydrogeological characters.

  15. [A survey on nosocomial tuberculosis infection control in hospitals in Osaka City].

    PubMed

    Shimouchi, Akira; Konishi, Shozaburo; Tanaka, Takashi

    2005-12-01

    To ascertain nosocomial tuberculosis (TB) infection control practice in hospitals in Osaka City. A questionnaire was distributed in the orientation meeting and collected at the occasion of medical inspection in all 196 hospitals in Osaka City in 2003. TB patients were diagnosed in about half of hospitals in the past 3 years. Basic TB infection control measures were taken in the majority of hospitals; such as chest X-ray screening for all inpatients, health check for employees, tuberculin skin test (TST) for newly employed staff, and nomination of a person in charge of TB infection control. Control measures were practiced more often in hospitals where TB patients were diagnosed, such as "fiberoptic bronchoscopy is to be conducted last in the working hours to avoid contamination of TB bacilli in a room," "TST (including two-step method) for all newly employed staff," "Staff wear N95 mask when they deal with TB patients/suspects," and the differences were statistically significant. It is necessary in hospitals in Osaka City to strengthen nosocomial TB infection control as TB patients were diagnosed in about half of hospitals in the past 3 years. Low cost infection control measures were undertaken more often among hospitals where TB patients were diagnosed. Introduction of high cost equipment or improvement of facilities should be considered in hospitals of high TB risk. Guidelines formulated based on analysis of the survey should facilitate all hospitals to introduce at least low cost effective tuberculosis infection control measures.

  16. DRAGON-West Japan campaign in 2012: regional aerosol measurements over Osaka

    NASA Astrophysics Data System (ADS)

    Sano, I.; Mukai, S.; Holben, B. N.; Nakata, M.; Yonemitsu, M.; Sugimoto, N.; Fujito, T.; Hiraki, T.; Iguchi, N.; Kozai, K.; Kuji, M.; Muramatsu, K.; Okada, Y.; Okada, Y.; Sadanaga, Y.; Tohno, S.; Toyazaki, Yasuo; Yamamoto, Kouhei

    2012-11-01

    It is known that the aerosol distribution in Asia is complicated due to the increasing emissions of anthropogenic aerosols in association with economic growth and natural dust significantly varied with the seasons. Therefore it is clear that local spatially and temporally resolved measurements of atmospheric aerosols in Asian urban city are necessary. Since Osaka, Kobe, Kyoto, and Nara are located in very close each others (all cities are included in around 70×70 km2 area). The population of the region is around 13 millions including neighbor prefectures, accordingly air quality in this region is slightly bad in comparison with the remote area. Furthermore, in recent years, Asian dusts and anthropogenic small particles some times transported from China and cover these cities throughout year. DRAGON (Distributed Regional Aerosol Gridded Observation Network) is a project of dense sun/sky radiometer network in the urban area. The DRAGON-West Japan field campaign was performed over Osaka and neighbor cities with 7 AERONET instruments from March to end of May in 2012. As results, DRAGON measurements indicate small differences among the values of AOT over Osaka region.

  17. Temporal trends in out-of-hospital cardiac arrest survival outcomes between two metropolitan communities: Seoul-Osaka resuscitation study.

    PubMed

    Ro, Young Sun; Shin, Sang Do; Kitamura, Tetsuhisa; Lee, Eui Jung; Kajino, Kentaro; Song, Kyoung Jun; Nishiyama, Chika; Kong, So Yeon; Sakai, Tomohiko; Nishiuchi, Tatsuya; Hayashi, Yasuyuki; Iwami, Taku

    2015-06-09

    The objective of this study was to compare the temporal trends in survival after out-of-hospital cardiac arrest (OHCA) between two large metropolitan communities in Asia and evaluate the factors affecting survival after OHCA. A population-based prospective observational study. The Cardiovascular Disease Surveillance (CAVAS) project in Seoul and the Utstein Osaka Project in Osaka. A total of 36,292 resuscitation-attempted OHCAs with cardiac aetiology from 2006 to 2011 in Seoul and Osaka (11,082 in Seoul and 25,210 in Osaka). The primary outcome was neurologically favourable survival. Trend analysis and multivariable Poisson regression models were conducted to evaluate the temporal trends in survival of two communities. During the study period, the overall neurologically favourable survival was 2.6% in Seoul and 4.6% in Osaka (p<0.01). In both communities, bystander cardiopulmonary resuscitation (CPR) rates increased significantly from 2006 to 2011 (from 0.1% to 13.1% in Seoul and from 33.3% to 41.7% in Osaka). OHCAs that occurred in public places increased in Seoul (12.5% to 20.1%, p for trend <0.01) and decreased in Osaka (13.5% to 10.5%, p for trend <0.01). The proportion of OHCAs defibrillated by emergency medical service (EMS) providers was only 0.4% in 2006 but increased to 17.5% in 2011 in Seoul, whereas the proportion in Osaka decreased from 17.7% to 13.7% (both p for trend <0.01). Age-adjusted and gender-adjusted rates of neurologically favourable survival increased significantly in Seoul from 1.4% in 2006 to 4.3% in 2011 (adjusted rate ratio per year, 1.17; p for trend <0.01), whereas no significant improvement was observed in Osaka (3.6% in 2006 and 5.1% in 2011; adjusted rate ratio per year, 1.03; p for trend=0.08). Survivals after OHCA were increased in Seoul while remained constant in Osaka, which may have been affected by the differences and improvements of patient, community, and EMS system factors. Published by the BMJ Publishing Group Limited. For

  18. The 2014 measles outbreak in Osaka An epidemiological study for the elimination of measles.

    PubMed

    Yagi, Yoshina; Higashino, Hirohiko; Yoshida, Hideki; Hirokawa, Hidetetsu; Okumachi, Akinori; Takano, Masako; Nobuta, Mari; Matuoka, Taro; Sasai, Yasunori; Fukushima, Wakaba; Tanaka, Tomoyuki

    2015-01-01

    To examine and analyze the spread of measles in Osaka in 2014 and determine effective measures to prevent such occurrences. We analyzed 47 cases of measles reported in Osaka, including one measles patient living in another prefecture where there was an outbreak. We focused on age distribution, the number of patients reported each week, estimated infection routes, history of measles vaccination, detection of viruses, and number of days it took to report the case after the onset of measles. Patients aged 20-39 years accounted for 24 cases (51.1%). The number of patients reported started from 2nd week with relatively broad peak to 27(th) week, and the measles epidemic was brought under control in the 47(th) week. Among the 47 cases, no source could be identified in 16 cases (34.0%). Household exposure was the main cause of the infection (25.5%), followed by imported cases (21.3%). Eighty-three percent of the overall patients had not received a measles vaccination at all or it was unclear whether they previously had been vaccinated. Genotype B3, H1, and D8 were detected in our patients and these genotypes originated overseas. It took significantly more days, from the onset of measles, for the case to be reported in patients aged 15 years and over compared with those aged under 15 years (P=0.001). For eradicating measles in Osaka, it is important to raise awareness about this issue among medical institutions, especially institutions for adults, in order for them to report cases as soon as possible, upon discovery in their patients. In addition, "catch-up" supplementary immunizations are effective for all people, including adults who are susceptible to measles.

  19. Strengthened tuberculosis control programme and trend of multidrug resistant tuberculosis rate in Osaka City, Japan

    PubMed Central

    Ohkado, Akihiro; Matsumoto, Kenji; Komukai, Jun; Yoshida, Hideki; Ishikawa, Nobukatsu

    2013-01-01

    Osaka City has the highest tuberculosis (TB) notification rates in Japan. In the period 1999–2003, the TB control programme was strengthened, and the Stop TB Strategy was implemented to reduce the number of notified cases. The objective of this study was to assess the effect of these control activities in Osaka City, including the implementation of directly observed treatment (DOT), by analysing TB surveillance and routinely collected data. We reviewed the surveillance data of all sputum smear-positive pulmonary tuberculosis (PTB) cases registered in the Osaka City Public Health Office from 2001 to 2008 and data collected from the routine TB programme. The DOT implementation rate increased from 0% in 2001 to 68% in 2008 for smear-positive PTB cases of the general public and to 61% for all PTB cases of the homeless. The proportion of smear-positive PTB cases that had treatment failure and default combined, declined from 8.0% (52 of 650) in 2001 to 3.6% (20 of 548) in 2006. The proportion of cases among the homeless with previous treatment declined from 28% in 2001 to 15% in 2008. The proportion of cases with multidrug resistant-TB (MDR-TB) among those without previous treatment declined from 1.7% in 2001 to 0.9% in 2008. It is logical that reduction in the failure and default rate would lead to the reduction of cases with previous treatment and TB transmission, including resistant TB, therefore to the reduction of MDR-TB rates. PMID:23908949

  20. Atomic-resolution 3D structure of amyloid β fibrils: The Osaka mutation

    DOE PAGES

    Schutz, Anne K.; Wall, Joseph; Vagt, Toni; ...

    2014-11-13

    Despite its central importance for understanding the molecular basis of Alzheimer's disease (AD), high-resolution structural information on amyloid β-peptide (Aβ) fibrils, which are intimately linked with AD, is scarce. We report an atomic-resolution fibril structure of the Aβ 1-40 peptide with the Osaka mutation (E22Δ), associated with early-onset AD. The structure, which differs substantially from all previously proposed models, is based on a large number of unambiguous intra- and intermolecular solid-state NMR distance restraints

  1. Coprological survey of parasitic infections in pigs and cattle in slaughterhouse in Osaka, Japan.

    PubMed

    Matsubayashi, Makoto; Kita, Toshimasa; Narushima, Tsuguto; Kimata, Isao; Tani, Hiroyuki; Sasai, Kazumi; Baba, Eiichiroh

    2009-08-01

    A coprological survey was performed at a slaughterhouse in Osaka, Japan, from 2004 to 2007 on 129 pigs reared in 8 prefectures, and on 213 cattle reared in 21 prefectures. Eimeria spp., Trichuris suis, Ascaris suum and Metastrongylus spp. infections were found in 52 (40.3%), 32 (24.8%), 19 (14.7%) and 3 pigs (2.3%), respectively, while Eimeria spp., Capillaria bovis and Trichuris sp. infections were detected in 163 (76.5%), 15 (7.0%) and 8 cattle (3.8%), respectively. Our results suggest that environmentally resistant oocysts and eggs of parasites could be widespread at the farms examined.

  2. Occurrence and diversity of barnacles on international ships visiting Osaka Bay, Japan, and the risk of their introduction.

    PubMed

    Otani, M; Oumi, T; Uwai, S; Hanyuda, T; Prabowo, R E; Yamaguchi, T; Kawai, H

    2007-01-01

    The occurrence and diversity of barnacles attached to the hulls of two intercontinental bulk carriers were studied at the port in Osaka Bay, Japan, to assess the potential risk of introduction of exotic species to the inner part of the bay. Barnacles were sampled from the bulbous bows, near the midship draft marks, and around the propeller posts and rudders. Twenty-two species were found, with 14 of these not previously recorded in Osaka Bay, including four species not previously recorded elsewhere in Japan. From an assessment of environmental similarity between Osaka Bay and native ranges, of the 14 species, Elminius modestus and Amphibalanus variegatus were considered to have the highest risk of introduction to the inner part of the bay.

  3. Cancer incidence and mortality in Osaka, Japan: future trends estimation with an age-period-cohort model.

    PubMed

    Utada, Mai; Ohno, Yuko; Shimizu, Sachiko; Ito, Yuri; Tsukuma, Hideaki

    2012-01-01

    In previous studies we predicted future trends in cancer incidence for each prefecture in order to plan cancer control. Those predictions, however, did not take into account the characteristics of each prefecture. We therefore used the results of age-period-cohort analysis of incidence and mortality data of Osaka, and estimated the incidence and mortality of cancers at all sites and selected sites. The results reflect the characteristics of Osaka, which has and is expected to have large number of patients with liver cancer. We believe our results to be useful for planning and evaluating cancer control activities in Osaka. It would be worthwhile to base the estimation of cancer incidence and mortality in each prefecture on each population-based cancer registry.

  4. Achievements and Challenges in the US Summer English Program offered by the Graduate School of Engineering, Osaka University

    NASA Astrophysics Data System (ADS)

    Kunioshi, Nílson; Ashizawa, Shingo; Tsuji, Kiichiro

    As an extension of the subject “English for Engineers” offered by the Graduate School of Engineering to its students, a summer intensive technical English course is held every year in the United States. The contents of the summer program are customized to meet the needs of the engineering students of Osaka University, and from 2004 participants can get the credits corresponding to English for Engineers II, a subject that usually is taken in the second semester at Osaka University. The evolution in the contents of the summer program, first designed in 2003, as well as the achievements, further possible improvements and problems to be solved are analysed.

  5. Prevalence of insomnia among residents of Tokyo and osaka after the great East Japan earthquake: a prospective study.

    PubMed

    Sugiura, Hiroaki; Akahane, Manabu; Ohkusa, Yasushi; Okabe, Nobuhiko; Sano, Tomomi; Jojima, Noriko; Bando, Harumi; Imamura, Tomoaki

    2013-01-18

    The Great East Japan Earthquake occurred on March 11, 2011. Tokyo and Osaka, which are located 375 km and 750 km, respectively, from the epicenter, experienced tremors of 5.0 lower and 3.0 seismic intensity on the Japan Meteorological Agency scale. The Great East Japan Earthquake was the fourth largest earthquake in the world and was accompanied by a radioactive leak at a nuclear power plant and a tsunami. In the aftermath of a disaster, some affected individuals presented to mental health facilities with acute stress disorder (ASD) and/or post-traumatic stress disorder (PTSD). However, few studies have addressed mental stress problems other than ASD or PTSD among the general public immediately after a disaster. Further, the effects of such a disaster on residents living at considerable distances from the most severely affected area have not been examined. This study aimed to prospectively analyze the effect of a major earthquake on the prevalence of insomnia among residents of Tokyo and Osaka. A prospective online questionnaire study was conducted in Tokyo and Osaka from January 20 to April 30, 2011. An Internet-based questionnaire, intended to be completed daily for a period of 101 days, was used to collect the data. All of the study participants lived in Tokyo or Osaka and were Consumers' Co-operative Union (CO-OP) members who used an Internet-based food-ordering system. The presence or absence of insomnia was determined before and after the earthquake. These data were compared after stratification for the region and participants' age. Multivariate analyses were conducted using logistic regression and a generalized estimating equation. This study was conducted with the assistance of the Japanese CO-OP. The prevalence of insomnia among adults and minors in Tokyo and adults in Osaka increased significantly after the earthquake. No such increase was observed among minors in Osaka. The overall adjusted odds ratios for the risk of insomnia post-earthquake versus pre

  6. Nanocommunication design in graduate-level education and research training programs at Osaka University.

    PubMed

    Sekiya, Mizuki; An, SoonHwa; Ata, Masafumi

    2014-01-01

    After more than ten years of strategic investment research and development supported by government policies on science and technology, nanotechnology in Japan is making a transition from the knowledge creation stage of exploratory research to the stage of making the outcomes available for the benefit of society as a whole. Osaka University has been proactive in discussions about the relationship between nanotechnology and society as part of graduate and continuing education programs. These programs are intended to fulfill the social accountability obligation of scientists and corporations involved in R&D, and to deepen their understanding of the relationship between science and society. To meet those aims, the program has covered themes relating to overall public engagement relating to nanotechnology governance, such as risk management of nanomaterials, international standardization for nanotechnology, nanomeasurement, intellectual property management in an open innovation environment, and interactive communication with society. Nanotechnology is an emerging field of science and technology. This paper reports and comments on initiatives for public engagement on nanotechnology at Osaka University's Institute for NanoScience Design, which aims to create new technologies based on nanotechnology that can help realize a sustainable society.

  7. Nanocommunication design in graduate-level education and research training programs at Osaka University

    NASA Astrophysics Data System (ADS)

    Sekiya, Mizuki; An, SoonHwa; Ata, Masafumi

    2014-09-01

    After more than ten years of strategic investment research and development supported by government policies on science and technology, nanotechnology in Japan is making a transition from the knowledge creation stage of exploratory research to the stage of making the outcomes available for the benefit of society as a whole. Osaka University has been proactive in discussions about the relationship between nanotechnology and society as part of graduate and continuing education programs. These programs are intended to fulfill the social accountability obligation of scientists and corporations involved in R&D, and to deepen their understanding of the relationship between science and society. To meet those aims, the program has covered themes relating to overall public engagement relating to nanotechnology governance, such as risk management of nanomaterials, international standardization for nanotechnology, nanomeasurement, intellectual property management in an open innovation environment, and interactive communication with society. Nanotechnology is an emerging field of science and technology. This paper reports and comments on initiatives for public engagement on nanotechnology at Osaka University's Institute for NanoScience Design, which aims to create new technologies based on nanotechnology that can help realize a sustainable society.

  8. Distributions of nitrated polycyclic aromatic hydrocarbons in the sediment of Osaka Bay, Japan.

    PubMed

    Uno, Seiichi; Tanaka, Hiroyuki; Kokushi, Emiko; Bacolod, Eugene T; Koyama, Jiro

    2017-03-05

    The distributions of 15 nitrated polycyclic aromatic hydrocarbons (NPAHs) in sediments collected at 44 sites throughout Osaka Bay, Japan were examined. The highest total NPAHs, with a concentration of 1949ng/kg dry weight, were detected near the city of Amagasaki. Some sites near the cities of Osaka, Kishiwada, sand Sakai registered ng/kg levels of NPAHs, but individual NPAH concentrations were relatively lower than those in previous studies. The sources were estimated using principal component analysis, and NPAHs were derived from exhaust gases of automobiles and industries at some sites. However, our results suggest that it is difficult to estimate the source, especially in coastal areas near big cities and large industrial areas, because the generation pathways between parent polycyclic aromatic hydrocarbons (PAHs) and nitrated PAHs are slightly different, and the ratio of PAHs and NPAHs could not be accurately reflect the characters of sources in sediments especially at coastal areas with large-scale industrial zones. Copyright © 2017 Elsevier Ltd. All rights reserved.

  9. Travel-related illness at a tertiary care hospital in Osaka, Japan.

    PubMed

    Hadano, Yoshiro; Shirano, Michinori; Goto, Tetsushi

    2016-01-01

    We analyzed the travel-related health problems in persons returning to Japan from overseas. Data were extracted retrospectively for all patients visiting the infectious diseases department of Osaka City General Hospital, Osaka, Japan, between July 2012 and September 2013. There were 209 sick returning travelers during the period of the study. The median age of the subjects was 34.3 years, and the subjects consisted of 133 tourists (63.6%), 39 business travelers (18.7%), 17 expatriates (8.1%), 14 volunteer workers (6.7%), and four persons who visited friends and relatives (1.9%). The most visited destinations were Asia (n=162, 77.5%), including East Asia (n=26, 12.4%), Southeast Asia (n=116, 55.5%), South Asia (n=25, 12.0%), Central Asia (n=3, 1.4%), and Africa (n=30, 14.3%). The most commonly diagnosed diseases were gastrointestinal tract infection (n=81, 38.8%), dengue fever (n=26, 12.4%), and animal bites (n=26, 12.4%). Twenty-nine patients (13.8%) were hospitalized, mainly for dengue fever and gastrointestinal tract infection.

  10. Travel-related illness at a tertiary care hospital in Osaka, Japan

    PubMed Central

    Hadano, Yoshiro; Shirano, Michinori; Goto, Tetsushi

    2016-01-01

    We analyzed the travel-related health problems in persons returning to Japan from overseas. Data were extracted retrospectively for all patients visiting the infectious diseases department of Osaka City General Hospital, Osaka, Japan, between July 2012 and September 2013. There were 209 sick returning travelers during the period of the study. The median age of the subjects was 34.3 years, and the subjects consisted of 133 tourists (63.6%), 39 business travelers (18.7%), 17 expatriates (8.1%), 14 volunteer workers (6.7%), and four persons who visited friends and relatives (1.9%). The most visited destinations were Asia (n=162, 77.5%), including East Asia (n=26, 12.4%), Southeast Asia (n=116, 55.5%), South Asia (n=25, 12.0%), Central Asia (n=3, 1.4%), and Africa (n=30, 14.3%). The most commonly diagnosed diseases were gastrointestinal tract infection (n=81, 38.8%), dengue fever (n=26, 12.4%), and animal bites (n=26, 12.4%). Twenty-nine patients (13.8%) were hospitalized, mainly for dengue fever and gastrointestinal tract infection. PMID:27799812

  11. Incidence and survival trends for childhood cancer in Osaka, Japan, 1973-2001.

    PubMed

    Baba, Sachiko; Ioka, Akiko; Tsukuma, Hideaki; Noda, Hiroyuki; Ajiki, Wakiko; Iso, Hiroyasu

    2010-03-01

    Mortality for childhood cancer has declined in Osaka, as well as all over Japan, since the 1970s, but whether this decline can be explained by trends of incidence or survival of childhood cancer has not been examined. A total of 5960 malignant tumors diagnosed between 1973 and 2001 in children <15 years of age were registered at the Osaka Cancer Registry in Japan. The time trends for childhood cancer were analyzed over 29 years for incidence and 20 years for survival. Leukemia was the most common among childhood cancer for both sexes and accounted for one-third of all cases. The age-standardized annual incidence rate of all tumors was highest in 1988-1992: 155.1 per million for males and 135.9 for females. Five-year survival for all tumors improved from 50.1% in 1978-1982 to 73.0% in 1993-1997 for males and from 52.3% to 76.3% for females. Thus, the constant decline in mortality in childhood cancer was primarily due to improved survival between the 1970s and 1980s and reduced incidence after the 1990s.

  12. Scientific Grid activities and PKI deployment in the Cybermedia Center, Osaka University.

    PubMed

    Akiyama, Toyokazu; Teranishi, Yuuichi; Nozaki, Kazunori; Kato, Seiichi; Shimojo, Shinji; Peltier, Steven T; Lin, Abel; Molina, Tomas; Yang, George; Lee, David; Ellisman, Mark; Naito, Sei; Koike, Atsushi; Matsumoto, Shuichi; Yoshida, Kiyokazu; Mori, Hirotaro

    2005-10-01

    The Cybermedia Center (CMC), Osaka University, is a research institution that offers knowledge and technology resources obtained from advanced researches in the areas of large-scale computation, information and communication, multimedia content and education. Currently, CMC is involved in Japanese national Grid projects such as JGN II (Japan Gigabit Network), NAREGI and BioGrid. Not limited to Japan, CMC also actively takes part in international activities such as PRAGMA. In these projects and international collaborations, CMC has developed a Grid system that allows scientists to perform their analysis by remote-controlling the world's largest ultra-high voltage electron microscope located in Osaka University. In another undertaking, CMC has assumed a leadership role in BioGrid by sharing its experiences and knowledge on the system development for the area of biology. In this paper, we will give an overview of the BioGrid project and introduce the progress of the Telescience unit, which collaborates with the Telescience Project led by the National Center for Microscopy and Imaging Research (NCMIR). Furthermore, CMC collaborates with seven Computing Centers in Japan, NAREGI and National Institute of Informatics to deploy PKI base authentication infrastructure. The current status of this project and future collaboration with Grid Projects will be delineated in this paper.

  13. PREFACE: Proceedings of the International Conference on Highly Frustrated Magnetism, Osaka, Japan, 15 19 August 2006

    NASA Astrophysics Data System (ADS)

    Hiroi, Zenji; Tsunetsugu, Hirokazu; Kawamura, H.

    2007-04-01

    The Highly Frustrated Magnetism 2006 (HFM 2006) conference took place on 15-19 August 2006 at the Icho Kaikan of Osaka University, Osaka, Japan. This conference was the third one of the series, following the first one in Waterloo, Canada (HFM 2000) [1] and the second one in Grenoble, France (HFM 2003) [2]. The HFM 2006 conference was held as a satellite of the International Conference on Magnetism (ICM 2006) held on 20-25 August 2006 in Kyoto, Japan. The conference attracted 191 participants from all over the world. The number of participants of the HFM conference series has been increasing steadily, from about 80 participants for HFM 2000 and about 120 participants for HFM 2003, demonstrating that highly frustrated magnetism is a rapidly growing area for research in condensed matter physics. The HFM 2006 conference consisted of four plenary talks by H Takagi, F Mila, P Mendels and B D Gaulin, 18 invited presentations and about 120 poster presentations from all areas of frustrated magnetism. In the evening on the 18th of August, a special session about 'the kagome story' was given by M. Mekata, where participants learned about the history of early-day research on frustrated magnetism and the origin of the word 'kagome' (see the picture below). Kagome lattice in a traditional Japanese woven basket Kagome lattice from a Japanese traditional woven bamboo basket. During the conference period, many stimulating discussions were held both inside and outside the conference room. The subjects covered in the conference included: Quantum frustrated magnetism and spin liquids Novel ordering of geometrically frustrated magnets Itinerant frustrated systems and novel superconductivity Spin glasses and random magnets Frustration effect on the coupling to lattice, orbital and charge degrees of freedom Exotic phenomena induced by macroscopic degeneracy Field effect on frustrated magnetism etc. This special issue of Journal of Physics: Condensed Matter is devoted to the proceedings

  14. Investigation of Spatial Clustering of Biliary Tract Cancer Incidence in Osaka, Japan: Neighborhood Effect of a Printing Factory

    PubMed Central

    Ito, Yuri; Nakaya, Tomoki; Ioka, Akiko; Nakayama, Tomio; Tsukuma, Hideaki; Uehara, Shinichiro; Kogawa Sato, Kyoko; Endo, Ginji; Hayashi, Tomoshige

    2016-01-01

    Background In 2013, an unusually high incidence of biliary tract cancer among current or former workers of the offset color proof printing department of a printing company in Osaka, Japan, was reported. The purpose of this study was to examine whether distance from the printing factory was associated with incidence of biliary tract cancer and whether incident biliary tract cancer cases clustered around the printing factory in Osaka using population-based cancer registry data. Methods We estimated the age-standardized incidence ratio of biliary tract cancer according to distance from this printing factory. We also searched for clusters of biliary tract cancer incidence using spatial scan statistics. Results We did not observe statistically significantly high or low standardized incidence ratios for residents in each area categorized by distance from the printing factory for the entire sample or for either sex. The scan statistics did not show any statistically significant clustering of biliary tract cancer incidence anywhere in Osaka prefecture in 2004–2007. Conclusions There was no statistically significant clustering of biliary tract cancer incidence around the printing factory or in any other areas in Osaka, Japan, between 2004 and 2007. To date, even if some substances have diffused outside this source factory, they do not appear to have influenced the incidence of biliary tract cancer in neighboring residents. PMID:26902168

  15. Investigation of Spatial Clustering of Biliary Tract Cancer Incidence in Osaka, Japan: Neighborhood Effect of a Printing Factory.

    PubMed

    Ito, Yuri; Nakaya, Tomoki; Ioka, Akiko; Nakayama, Tomio; Tsukuma, Hideaki; Uehara, Shinichiro; Kogawa Sato, Kyoko; Endo, Ginji; Hayashi, Tomoshige

    2016-09-05

    In 2013, an unusually high incidence of biliary tract cancer among current or former workers of the offset color proof printing department of a printing company in Osaka, Japan, was reported. The purpose of this study was to examine whether distance from the printing factory was associated with incidence of biliary tract cancer and whether incident biliary tract cancer cases clustered around the printing factory in Osaka using population-based cancer registry data. We estimated the age-standardized incidence ratio of biliary tract cancer according to distance from this printing factory. We also searched for clusters of biliary tract cancer incidence using spatial scan statistics. We did not observe statistically significantly high or low standardized incidence ratios for residents in each area categorized by distance from the printing factory for the entire sample or for either sex. The scan statistics did not show any statistically significant clustering of biliary tract cancer incidence anywhere in Osaka prefecture in 2004-2007. There was no statistically significant clustering of biliary tract cancer incidence around the printing factory or in any other areas in Osaka, Japan, between 2004 and 2007. To date, even if some substances have diffused outside this source factory, they do not appear to have influenced the incidence of biliary tract cancer in neighboring residents.

  16. Long- and/or short-range transportation of local Asian aerosols in DRAGON-Osaka Experiment

    NASA Astrophysics Data System (ADS)

    Nakata, M.; Sano, I.; Mukai, S.; Holben, B. N.

    2013-12-01

    This work intends to demonstrate the spatial and temporal variation of atmospheric particles in East Asia, especially around AERONET (Aerosol Robotics Network) -Osaka site during Dragon Asia period in the spring of 2012, named Dragon-Osaka. It is known that the air pollution in East Asia becomes to be severe due to both the increasing emissions of the anthropogenic aerosols associated with economic growth and the complicated behavior of natural aerosols. Thus the precise observations of atmospheric particles in East Asia are desired. Osaka is the second big city in Japan and a typical Asian urban area. The population of the region is around 20 millions including neighbor prefectures. Therefore, air quality in the region is slightly bad compared to remote area due to industries and auto mobiles. In recent years, Asian dusts and anthropogenic small particles transported from China and cover those cities throughout year. AERONET Osaka site was established in 2002 on the campus of Kinki University. Nowadays, LIDAR (Light Detection and Ranging), an SPM sampler (SPM-613D, Kimoto Electric, Japan) and others are available on the roof of a building. The site data are useful for algorithm development of aerosol retrieval over busy city. On the other hand, human activities in this region also emit the huge amount of pollutions, thus it is needed to investigate the local distribution of aerosols in this region. In order to investigate change of aerosol properties, PM-individual analysis is made with scanning electron microscope (SEM) coupled with energy dispersive X-ray analyzer (EDX). SEM/EDX is an effective instrument to observe the surface microstructure and analyze the chemical composition of such materials as metals, powders, biological specimens, etc. We used sampling data from the SPM sampler at AERONET Osaka site. During a period of DRAGON-Asia, high concentrations of air pollutant were observed on the morning of March 11 in Fukue Island in the East China Sea. On the

  17. Volcanic? Non-Volcanic? Low-Frequency Earthquakes beneath Osaka Bay - Event Search from Continuous Records -

    NASA Astrophysics Data System (ADS)

    Aso, N.; Ide, S.

    2010-12-01

    Low frequency earthquakes (LFEs) and tremors are observed in Nankai subduction zone, Japan. They are recognized to occur upon the subducting Philippine Sea plate. On the other hand, LEFs apart from plate boundary surface are also known (e.g. Ohmi and Obara, 2002). Most of them are distributed around volcanoes with some exceptions. Ones of the exceptions are LEFs occurring beneath Osaka Bay area between Kinki and Shikoku regions. These LFEs occur near the extension of tremor belt in Shikoku, and they are also close to the tear of Philippine Sea plate between Kinki and Shikoku regions (Ide et al., GRL in press). In addition, the epicenters of these LFEs are aligned toward north-northwest, the direction of the tear, and its extended line passes through the epicenter of the 1995 Kobe Earthquake. These facts suggest the hidden relations between LFEs, the subducting slab, and major inland earthquakes. The waveforms of the LFEs beneath Osaka Bay often have distinct spectral peak around 2Hz, unlike LFEs in subduction zones. This feature is common to some volcanic tremors. It is also suggested that mantle-derived water is blowing off along the wake of the slab tear, and some fluid likely exists beneath Osaka Bay. The LFEs have been detected by routine analysis of the Japan Meteorological Agency (JMA). These are small portion of overall activities, because the routine analysis is not optimized to detect small low frequency events in noisy data. To figure out whole activities of LFEs, we apply Matched Filter Analysis (Gibbons and Ringdal, 2006; Shelly et al., 2007) to continuous waveform records, using LFEs detected by JMA as template events. We used the 69 components in the 23 stations in Hi-net, maintained by the National Reserch Institute for Earth Science and Disaster Prevention. The waveforms are bandpass filtered between 2 and 8Hz. We calculated the cross-correlations of template LFEs and continuous records with 8s time window. An LFE is detected when the cross

  18. [The association between smoking and sputum smear-positive pulmonary tuberculosis in Osaka City].

    PubMed

    Matsumoto, Kenji; Arima, Kazuyo; Komukai, Jun; Danno, Katsura; Yoshida, Hideki; Hirota, Satoshi; Koda, Shinichi; Terakawa, Kazuhiko; Shimouchi, Akira

    2012-08-01

    This study aimed to analyze and evaluate the association between tuberculosis (TB) and smoking in order to obtain basic information for the control of smoking. Of the 637 patients with sputum smear-positive pulmonary tuberculosis who were newly registered in Osaka City in 2009, 581 patients whose smoking status was identified were selected as study subjects. Data on the following were collected: patient characteristics, presence or absence of underlying conditions, patient's delay and doctor's delay in the diagnosis of TB, presence or absence of cavities, and degree of smear positivity. The patients were divided into the following three groups according to their smoking status: (1) never smokers (those who have never smoked), (2) former smokers (those who had smoked, but quitted), and (3) current smokers (those who smoke currently). (1) PATIENT CHARACTERISTICS: The subjects consisted of 413 males and 168 females, with mean ages of 65.7, 55.4, and 70.2 years for never smokers, current smokers, and former smokers, respectively. (2) Comparison with the national adult smoking rate (National health and nutrition survey 2009, Ministry of Health, Labour and Welfare): The prevalence of current smoking among male patients with sputum smear-positive pulmonary TB in Osaka was 62.4-82.4% among men in their 20s to 60s, and 27.5% among men in their 70s, which is higher than the national average. For female patients, the prevalence of current smoking was 46.2% among women in their 20s and 45.5% among women in their 30s, which is clearly higher than the national average. This was also true for those aged 40 years or older. (3) Severity of TB disease and smoking status: The presence of a cavity was significantly associated with being a male patient, being a current smoker, and longer patient's delay. Sputum smear grades (2+) and (3 +) were significantly correlated with being under 59 years old, being a current smoker, and longer patient's delay. The prevalence of current smokers

  19. Evaluation of submarine groundwater discharge in coastal aquifers at Osaka Bay, Japan by numerical simulation

    NASA Astrophysics Data System (ADS)

    Yasumoto, J.; Jinno, K.; Onodera, S.; Ishitobi, T.; Taniguchi, M.

    2008-12-01

    In recent years, the coastal marine ecosystems have been deteriorated by the human activities and fisheries. One of the causes of this deteriorating situation is due to the increase of nutrient fluxes caused by the fertilizers and wastewater through the surface water and groundwater discharges from the residential and agricultural areas into coastal areas. In recent studies, it is recognized that the groundwater which contains nutrients can have a significant influence on coastal ecosystems. Submarine groundwater discharge (SGD) consists of terrestrial fresh groundwater and recirculated seawater which circulate across the aquifer-ocean interface. Recirculating seawater, which often constitutes a large portion of the total SGD, is an important component as it transports not only salt but also other chemicals from the ocean to the aquifer. Near the shore, seawater recirculation across the interface is driven primarily by tidal oscillations, waves and density variations between fresh groundwater and seawater. Recent numerical simulations show the formation of water circulations in the aquifers near the shoreline owing to the tidal oscillations. However, these calculation results do not compare with a field observation and are not necessarily an enough verification. The objective of this study is to evaluate the SGD mechanism in the Omaehama, Osaka bay under the influence of tidal effects. The developed numerical model was verified by comparing the results with the observed SGD in the Osaka bay. The study area is located in the coast of Omaehama, Osaka, Bay, Nishinomiya citiy, Japan. The automated seeepage meters with diameter of 500mm and piezometer with diameter of 13mm were installed to evaluate water dynamics below the beach slop. Electric conductivity of the pore water were also observed to evaluate the terrestrial groundwater among SGD duaring one tidal cycle. The numerical model is based on the groundwater flow equation for saturated-unsaturated fluid flow and

  20. Distinct genetic clades of enterovirus D68 detected in 2010, 2013, and 2015 in Osaka City, Japan.

    PubMed

    Kaida, Atsushi; Iritani, Nobuhiro; Yamamoto, Seiji P; Kanbayashi, Daiki; Hirai, Yuki; Togawa, Masao; Amo, Kiyoko; Kohdera, Urara; Nishigaki, Toshinori; Shiomi, Masashi; Asai, Sadasaburo; Kageyama, Tsutomu; Kubo, Hideyuki

    2017-01-01

    The first upsurge of enterovirus D68 (EV-D68), a causative agent of acute respiratory infections (ARIs), in Japan was reported in Osaka City in 2010. In this study, which began in 2010, we surveyed EV-D68 in children with ARIs and analyzed sequences of EV-D68 strains detected. Real-time PCR of 19 respiratory viruses or subtypes of viruses, including enterovirus, was performed on 2,215 specimens from ARI patients (<10 years of age) collected between November 2010 and December 2015 in Osaka City, Japan. EV-D68 was identified in 18 enterovirus-positive specimens (n = 4 in 2013, n = 1 in 2014, and n = 13 in 2015) by analysis of viral protein 1 (VP1) or VP4 sequences, followed by a BLAST search for similar sequences. All EV-D68 strains were detected between June and October (summer to autumn), except for one strain detected in 2014. A phylogenetic analysis of available VP1 sequences revealed that the Osaka strains detected in 2010, 2013, and 2015 belonged to distinct clusters (Clades C, A, and B [Subclade B3], respectively). Comparison of the 5' untranslated regions of these viruses showed that Osaka strains in Clades A, B (Subclade B3), and C commonly had deletions at nucleotide positions 681-703 corresponding to the prototype Fermon strain. Clades B and C had deletions from nucleotide positions 713-724. Since the EV-D68 epidemic in 2010, EV-D68 re-emerged in Osaka City, Japan, in 2013 and 2015. Results of this study indicate that distinct clades of EV-D68 contributed to re-emergences of this virus in 2010, 2013, and 2015 in this limited region.

  1. [TUBERCULOSIS SCREENING BY CHEST RADIOGRAPHY AMONG INTERNATIONAL STUDENTS AT JAPANESE LANGUAGE SCHOOLS IN OSAKA CITY].

    PubMed

    Tsuda, Yuko; Matsumoto, Kenji; Komukai, Jun; Furukawa, Kanae; Saito, Kazumi; Shimouchi, Akira

    2015-10-01

    With a broader aim of controlling pulmonary tuberculosis (TB) among foreigners, here, we have reported the findings of chest radiography screening for TB among international students at Japanese language schools in Osaka city. Between April 2011 and December 2013, 4,529 international students from 19 Japanese language schools in Osaka city underwent chest radiography for TB screening. The chest radiographs were studied in reference to the student's sex, age, nationality, and date of entry to Japan as well as any health conditions present at the time of screening. We further analyzed the bacterial information and pulmonary TB classification based on chest radiography findings of students who were identified to be positive for TB. Information on the implementation of health education was also gathered. The results revealed that 52.5% of the students who underwent chest radiography came from China, 20.3 % from South Korea, and 16.3% from Vietnam. Of the students, 52.9% were male and 47.1% were female. The median age of students was 23 years (range: 14-70 years). The median number of days from the first date of entry to Japan up until the radiography screening was 63 days. Based on the chest radiography findings, 71 students (1.6%) were suspected to have TB; however, further detailed examination confirmed that 19 students (0.4%) had active TB. This percentage is significantly higher than the 0.1% TB identification rate among residents in Osaka city of the same time period (P<0.001), which was also determined by chest radiography. The median age of the 19 TB positive patients was 23 years. Among them, 14 (73.7%) were male. The median time from the date of entry to Japan to the date of the chest radiography screening was 137 days. For 16 of those students, the entry to Japan was within 1 year of the radiography. Of the 19 TB positive patients, 16 (84.2%) did not have respiratory symptoms, 15 (79.0%) had sputum smear negative results, and 17 (89.5%) had no cavity. Health

  2. Pulse radiolysis system of OPU-LINAC in RIAST, Osaka Prefecture University

    NASA Astrophysics Data System (ADS)

    Kojima, Takao; Taniguchi, Ryoichi; Furuta, Masakazu; Okuda, Shuichi; Hara, Masayuki; Fujita, Shin'ichi

    2004-09-01

    Micro- to milli-second pulse radiolysis apparatus using short electron pulse form 18 MeV linear accelerator (Linac) is in-service at the Research institute for advanced science and technology (RIAST), Osaka Prefecture University. This apparatus is an effective tool, not only for investigation of primary process on radiation chemistry, but also for research of electron transfer mechanism playing an important role in chemistry and bioscience. This apparatus is composed of an 18 MeV electron linear accelerator (electron pulse duration: about 4 μs) and a transient light absorption measurement system. We introduce the outline of this system, transient absorption spectrum of thiocyanate aqueous solution as an example of measured data and future plan.

  3. Detection of Histamine in Fish and Fishery Products in Osaka Prefecture (Fiscal 2015 Report).

    PubMed

    Awazu, Kaoru; Takatori, Satoshi; Kakimoto, Sachiko; Nomura, Chie; Masayama, Atsushi; Yamaguchi, Mizuka; Kakimoto, You; Kajimura, Keiji

    2017-01-01

    Histamine food poisoning is caused by ingestion of spoiled fish containing high levels of histamine. This paper reports cases in which histamine was detected in Osaka prefecture in fiscal year 2015 in a survey of fish and fishery products on the market and the food poisoning. A suspected case of histamine food poisoning was also evaluated to investigate the cause and minimize further problems. Histamine in food was separated on SPE cartridge columns, and analyzed after derivatization with fluorescamine by means of HPLC-FL. Histamine was detected in some fishery products on the market and in food that had caused poisoning. The samples in which histamine was detected were semi-dried whole round herring (Urumeiwashi-maruboshi), mackerel (Saba) and sardine dumpling (Iwashi-tsumire). These foods were the main causes of histamine food poisoning according to the report of the Ministry of Health, Labour and Welfare, Government of Japan.

  4. Comparison of survival of adolescents and young adults with hematologic malignancies in Osaka, Japan.

    PubMed

    Nakata-Yamada, Kayo; Inoue, Masami; Ioka, Akiko; Ito, Yuri; Tabuchi, Takahiro; Miyashiro, Isao; Masaie, Hiroaki; Ishikawa, Jun; Hino, Masayuki; Tsukuma, Hideaki

    2016-01-01

    The survival gap between adolescents and young adults (AYAs) with hematological malignancies persists in many countries. To determine to what extent it does in Japan, we investigated survival and treatment regimens in 211 Japanese AYAs (15-29 years) in the Osaka Cancer Registry diagnosed during 2001-2005 with hematological malignancies, and compared adolescents (15-19 years) with young adults (20-29 years). AYAs with acute lymphoblastic leukemia (ALL) had a poor 5-year survival (44%), particularly young adults (29% vs. 64% in adolescents, p = 0.01). Additional investigation for patients with ALL revealed that only 19% of young adults were treated with pediatric treatment regimens compared with 45% of adolescents (p = 0.05). Our data indicate that we need to focus on young adults with ALL and to consider establishing appropriate cancer care system and guidelines for them in Japan.

  5. Sustainability Science Educational Program as Integrated Disciplinary Education : Practices and Lessons at Osaka University

    NASA Astrophysics Data System (ADS)

    Uwasu, Michinori; Shimoda, Yoshiyuki

    As global threats such as climate change and economic crisis have been emerging, the demand for the establishment of integrated disciplinary education programs is increasing. The Research Institute for Sustainability Science (RISS) at Osaka University started a new program on sustainability in October 2007. The RISS program addresses the ways to utilize knowledge effectively to understand the dynamic interactions between nature and human society. This paper first overviews the RISS Program for Sustainability Science. The paper then discusses the main problems as well as attempts and efforts to challenge those issues. Although issues including institutional barriers and faculty development yet remain in promoting integrated education, the RISS program functions as a platform to disseminate the idea of sustainability science across the university.

  6. [Differences in influenza epidemics in Osaka City--epidemiological surveillance of infectious disease].

    PubMed

    Murakami, T; Haruki, K; Seto, Y; Kimura, T; Shibe, K; Minoshiro, S

    1994-05-01

    Influenza viruses in outpatients with influenza symptoms in Osaka City were analyzed in an epidemiological surveillance of infectious disease between 1989 and 1993. During influenza epidemics a mixed prevalence of several types of influenza viruses existed. Three types of influenza viruses, AH1, AH3 and B, were isolated during the 1990/1991 season. Remarkably the three types of viruses were discovered in samplings collected on the same day and within a narrow area inside a radius of 800-1,000m from the surveyed hospitals. Different types of viruses were detected between brothers and among school children from same housing complexes. Influenza AH3 viruses detected in 1992/1993 season differed in antigenicity from those detected in the 1990/1991 and 1991/1992 seasons. Therefore it appears that mutation of the AH3 virus contributed to the large-scale influenza epidemic which occurred in the 1992/1993 season.

  7. Distribution of Candida species isolated from blood cultures in hospitals in Osaka, Japan.

    PubMed

    Morii, Daiichi; Seki, Masafumi; Binongo, José N; Ban, Ryoichi; Kobayashi, Atsuko; Sata, Makoto; Hashimoto, Shigeki; Shimizu, Junzo; Morita, Shunji; Tomono, Kazunori

    2014-09-01

    Candida species are clinically important causes of bloodstream infections because their mortality is very high. Given that some species of Candida are azole-resistant, identifying the distributions of Candida species could facilitate the formulation of an appropriate empirical antifungal therapy. It has been shown that the distribution varies depending on the continent, country, city, and hospital. In this paper, we describe the distributions of species in hospitals in northern Osaka, Japan. We evaluated blood culture results obtained from six tertiary hospitals in the northern Osaka area between 2004 and 2011. We also obtained comorbidity information from the patients' hospital medical records. Kaplan-Meier curves were drawn to compare the risk of death related to the different species. Of the 165 cases of candidemia confirmed by blood culture, 66% were male and the mean age was 62 years (range = 0-96). Overall, Candida albicans comprised 70 cases (43%), followed by Candida parapsilosis with 36 cases (22%), Candida glabrata with 25 cases (15%), Candida tropicalis with 11 cases (7%), Candida krusei with 10 cases (6%), and other Candida species with 13 cases (8%). C. tropicalis had higher associated mortality than other species, although it was not statistically significant. C. albicans was the most frequently isolated species, but the proportion of non-albicans Candida species was not negligible. The relatively high frequency of non-albicans Candida species distinguished the Japanese distribution from other areas. This characteristic distribution may have important implications when formulating an empirical antifungal therapy for Japanese clinical practice. Copyright © 2014 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

  8. Human parechovirus infections and child myositis cases associated with genotype 3 in Osaka City, Japan, 2014.

    PubMed

    Yamamoto, Seiji P; Kaida, Atsushi; Naito, Takuto; Hosaka, Taisuke; Miyazato, Yusuke; Sumimoto, Shin-ichi; Kohdera, Urara; Ono, Atsushi; Kubo, Hideyuki; Iritani, Nobuhiro

    2015-11-01

    Human parechovirus (HPeV) infects humans early in life and typically causes asymptomatic or mild diseases such as gastrointestinal and respiratory illness but sometimes leads to more serious consequences in neonates and young infants. In 2014, we detected HPeV from 38 patients by real-time reverse transcription-PCR in Osaka City, Japan, and 33 HPeV strains were genotyped based on their VP1 sequences. HPeV genotype 3 (HPeV-3) was the most prevalent and accounted for 22 cases (66.7%) followed by nine HPeV-1 (27.3%), one HPeV-2 (3.0%) and one HPeV-4 (3.0%). Phylogenetic analysis revealed that detected HPeV-3 strains were divided into three genetically distinct groups. One was characterized by a novel single amino acid deletion mutation at the N terminus of the 2A protein as well as the VP1 sequence, whereas the others were closely related to HPeV-3 strains detected in Japan in either 2008 or 2011. These HPeV-3 groups were detected from patients with various symptoms including three myositis cases. Recent papers have demonstrated that HPeV-3 was the aetiological agent for epidemic myalgia exclusively among adults from Yamagata Prefecture in Japan. Here, we provide clinical details and episodes of three myositis patients including an adult and two children in Osaka City, Japan. Our results suggest that HPeV-3 is a causative agent of myositis not only in adults but also in children.

  9. Effect of surrounding fault on distributed fault of blind reverse fault in sedimentary basin - Uemachi Faults, Osaka Basin, Southwest Japan -

    NASA Astrophysics Data System (ADS)

    Inoue, N.

    2012-12-01

    Several large cities and metropolitan areas, such as Osaka and Kobe are located in the Osaka basin, which has been filled by the Pleistocene Osaka group and the later sediments. The basin is surrounded by E-W trending strike slip faults and N-S trending reverse faults. The N-S trending 42-km-long Uemachi faults traverse in the central part of the Osaka city. The various geological, geophysical surveys, such as seismic reflection, micro tremor, gravity surveys and deep boreholes, revealed the complex basement configuration along the Uemachi faults. The depth of the basement is shallow in the central part of the Osaka plain. The Uemachi faults are locates on the western side of the basement upland. In the central part of the Uemachi faults, the displacement decreases. The fault model of the Uemachi faults consists of the two parts, the north and south parts. The NE-SW trending branch faults, Suminoe and Sakuragawa flexures, are also recognized based on various surveys around the central part. Kusumoto et al. (2001) reported that surrounding faults enable to form the basement configuration without the Uemachi faults model based on a dislocation model. Inoue et al. (2011) performed various parameter studies for dislocation model and gravity changes based on simplified faults model, which were designed based on the distribution of the real faults. The model was consisted of 7 faults including the Uemachi faults. In this study, the Osaka-wan fault was considered for the dislocation model. The results show the basement configuration including NE-SW branch faults. The basement configuration differs from the subsurface structure derived from the investigation of abundance geotechnical borehole data around the central part of the Uemachi faults. The tectonic developing process including the erosion and sea level change are require to understanding the structure from the basement to the surface of the Uemachi Fault Zone. This research is partly funded by the Comprehensive

  10. Development of Electrothermal Pulsed Plasma Thrusters for Osaka-Institute-of-Technology Electric-Rocket-Engine onboard Small Space Ship

    SciTech Connect

    Ishii, Yushuke; Yamamoto, Tsuyoshi; Yamada, Minetsugu; Tahara, Hirokazu

    2008-12-31

    The Project of Osaka-Institute-of-Technology Electric-Rocket-Engine onboard Small Space Ship (PROITERES) was started at Osaka Institute of Technology. In PROITERES, a 10-kg small satellite with electrothermal pulsed plasma thrusters (PPTs), named JOSHO, will be launched in 2010. The main mission is powered flight of small satellite by electric thruster itself. Electrothermal PPTs were studied with both experiments and numerical simulations. An electrothermal PPT with a side-fed propellant feeding mechanism achieved a total impulse of 3.6 Ns with a repetitive 10000-shot operation. An unsteady numerical simulation showed the existence of considerable amount of ablation delaying to the discharge. However, it was also shown that this phenomenon should not be regarded as the 'late time ablation' for electrothermal PPTs.

  11. Development of Electrothermal Pulsed Plasma Thrusters for Osaka-Institute-of-Technology Electric-Rocket-Engine onboard Small Space Ship

    NASA Astrophysics Data System (ADS)

    Ishii, Yushuke; Yamamoto, Tsuyoshi; Yamada, Minetsugu; Tahara, Hirokazu

    2008-12-01

    The Project of Osaka-Institute-of-Technology Electric-Rocket-Engine onboard Small Space Ship (PROITERES) was started at Osaka Institute of Technology. In PROITERES, a 10-kg small satellite with electrothermal pulsed plasma thrusters (PPTs), named JOSHO, will be launched in 2010. The main mission is powered flight of small satellite by electric thruster itself. Electrothermal PPTs were studied with both experiments and numerical simulations. An electrothermal PPT with a side-fed propellant feeding mechanism achieved a total impulse of 3.6 Ns with a repetitive 10000-shot operation. An unsteady numerical simulation showed the existence of considerable amount of ablation delaying to the discharge. However, it was also shown that this phenomenon should not be regarded as the ``late time ablation'' for electrothermal PPTs.

  12. Research and Development of the Pulsed Plasma Rocket Engine System onboard Osaka Institute of Technology Micro Artificial Satellite

    NASA Astrophysics Data System (ADS)

    Tahara, Hirokazu; Naka, Masamichi; Takagi, Hiroki; Ikeda, Tomoyuki; Watanabe, Yosuke

    The Project of Osaka Institute of Technology Electric-Rocket-Engine onboard Small Space Ship (PROITERES) was started at Osaka Institute of Technology in 2007. In PROITERES, a micro satellite with electrothermal pulsed plasma thrusters (PPTs) will be launched in 2010. The main mission is the first powered flight of micro satellite by electric thruster all over the world. This study aims at improvement in performance by changing configuration of PPTs. The total impulse of about 5 Ns was achieved with a teflon cylindrical discharge chamber 9.0 mm in length and 1.0 mm in diameter in 53,000-shot operation with 2.43 J/shot. Finally, the engineering model of PPT system was developed, and it is under operation as final test.

  13. [IMPORTANCE OF HEALTH CARE FOR THE ERADICATION OF TUBERCULOSIS--Efforts Implemented in Nishinari Ward, Osaka City].

    PubMed

    Matsumoto, Kenji

    2015-01-01

    1) Changes in the incidence rate of tuberculosis in Osaka City and Nishinari Ward. The incidence rate of tuberculosis among people living in Osaka City (per 100,000 people) was 41.5 (number of patients: 1,109) in 2011--an approximately 50% decrease from 82.6 in 2001. However, the figure is 2.3 times higher than the national incidence rate of tuberculosis (17.7), and the highest of all ordinance-designated cities and prefectures. Osaka City consists of 24 wards, and the incidence rate of tuberculosis varies from ward to ward. Although the incidence rate of tuberculosis in Nishinari Ward in 2011 was 199.6 (number of patients: 242) and the highest by far in the city, the figure is approximately 50% of the incidence rate in 2001 (405.9). There were two other wards with the incidence rate of 50.0 or higher, and the lowest incidence rate was 22.4. The incidence rate of tuberculosis in the Airin area of Nishinari Ward is particularly high. Although the number of newly registered patients decreased from 336 to 128 over the past ten years, and the incidence rate significantly decreased from 1,120.0 to 426.7 (when the population of the area was estimated to be 30,000), it is still 24.1 times higher than the national incidence rate. 2) Basic guidelines for tuberculosis strategy developed by Osaka City. Osaka City has developed basic guidelines for tuberculosis strategy to address patients with tuberculosis and eradicate the disease. The first and second periods of the basic guidelines for tuberculosis strategy were ten years from 2001 and 2011, respectively. The overall objective of these basic guidelines was to significantly reduce the incidence rate of tuberculosis, and numerical targets related to basic policies and specific activities were set to accomplish the goal. The basic guidelines allow Osaka City, including its public health centers, to implement measures against tuberculosis as a municipal project. 3) Assessment of the City's efforts. The measures were assessed

  14. [Life-style and cancer prevention. Activities of the Department of Cancer Prevention, Osaka Cancer Prevention and Detection Center].

    PubMed

    Oshima, A; Nakamura, M

    1990-02-01

    The role of the Department of Cancer Prevention, Osaka Cancer Prevention and Detection Center which was established in 1987 is to conduct practical research works in the area of primary prevention of cancer through life-style modification. We have so far examined the applicability and efficacy of such tools as population-based smoking cessation contest, nicotine gum, health risk appraisal and "Know Your Body" program. The outline of our activities and future plans are introduced.

  15. Landform, artificial and tidal effects for stream water chemistry of the Neyagawa river systems in the Osaka Plain, Japan

    NASA Astrophysics Data System (ADS)

    Yokoo, Yoriko; Shima, Yuka

    2016-04-01

    We determined the elemental compositions of stream water of the Neyagawa river systems in the Osaka Plain, Japan. The river water were enriched in Na+ and HCO3-in the southeast part of the Osaka Plain and in Ca2+ and HCO3- in the upper stretches of the Neyagawa river systems. These results indicate that these ionic compositions are derived mainly from geological inputs from the drainage basins. The river water were rich in Na+ and Cl- in Hiranogawa, Hiranogawa canal, the middle part of Neyagawa and the upper part of Furukawa. This ionic composition is largely attributable to artificial effect. Major ionic compositions of river water showed temporal variation in the center of the Osaka Plain. Tidal effect was shown in this area. The distribution of major ions and trace elements had a relationship to the factor such as geological, tidal, and artificial effect in each area. The origin of Na+, Cl-, SO42-, NO3-, Rb and Ni was artificial activity and tide. Geological input was mainly the provenance of HCO3-, Ca2+, Mg2+, Si and Ba. The concentrations of B, Li and Sr varied same as HCO3- and Ca2+ in the southeast part of the Osaka Plain. Moreover, the temporal variations of these elements showed the same trend as Na+and Cl-under the tidal effect area. These results suggest that it is possible to distinguish that tidal effect is reaching or not to the area by using the concentration ratios of B, Li and Sr to Na+.

  16. [Condom use staging and correlations among gay and bisexual men. A questionnaire survey of Osaka gay bar customers].

    PubMed

    Kaneko, Noriyo; Oomori, Sachiko; Tsuji, Hiroyuki; Oniduka, Tetsurou; Ichikawa, Seiichi

    2011-07-01

    This study aimed to clarify stages of condom use among gay and bisexual men at gay bars in Osaka and to assess relationships between condom use stage and attitudes and norms regarding HIV prevention. In this cross-sectional study, a self-administered survey was distributed to gay bar customers in Osaka in 2005. Completed surveys were received through the mail. Participants were divided into five groups based on condom use with regular and casual partners: pre-contemplation; contemplation; preparation; action; and maintenance. These five groups were merged into three groups: precontemplation; contemplation/preparation; and action/maintenance. Associations between these three groups of condom use stage and correlates were assessed. Among the 601 respondents (response rate, 44.9%), data from 546 men with lifetime sexual experience with men were used. Regarding stage distribution, the highest percentage of participants was in the pre-contemplation stage with a regular partner, and in the maintenance stage with casual partners. Activities of "MASH Osaka", a gay non-governmental organization, were widely recognized across all stages. The feeling of being unable to tell a partner to use a condom if the partner resisted condom use, being in a long-term relationship, difficulty using condoms when under the influence of drugs or alcohol, and self-efficacy all correlated with condom use stages. This study clarified condom use stages and correlations among gay and bisexual men at gay bars in Osaka. More research is needed to assess the reliability and validity of these scale items. Monitoring stage distributions and correlations with stages will be useful to evaluate HIV prevention activities.

  17. Sex differences in lung cancer survival: long-term trends using population-based cancer registry data in Osaka, Japan.

    PubMed

    Kinoshita, Fukuaki Lee; Ito, Yuri; Morishima, Toshitaka; Miyashiro, Isao; Nakayama, Tomio

    2017-09-01

    Several studies of sex differences in lung cancer survival have been reported. However, large-size population-based studies based on long-term observation are scarce. We investigated long-term trends in sex differences in lung cancer survival using population-based cancer registry data from Osaka, Japan. We analyzed 79 330 cases from the Osaka Cancer Registry (OCR) diagnosed between 1975 and 2007. We calculated 5-year relative survival in the six periods (1975-1980, 1981-1986, 1987-1992, 1993-1997, 1998-2002 and 2003-2007). To estimate the trends in sex differences in lung cancer survival throughout the study period, we applied a multivariate excess hazard model to control for confounders. The proportion of adenocarcinoma (ADC) and 5-year relative relative survival have increased for both sexes. Sex differences in lung cancer survival have widened over the period, especially in ADC and since the late 1990s. The excess hazard ratio of death within 5 years for males was 1.19 (95% CI: 1.16-1.21), adjusting for period at diagnosis, histologic type, stage, age group and treatment. We reported that females have better prognosis in lung cancer than males and the sex differences in lung cancer survival have become wider in Osaka, Japan. This can be partly explained by the sex differences in the proportions of histologic type and stage. Further studies considering other factors that influence sex differences in lung cancer survival are needed.

  18. Accumulation of endocrine disrupting chemicals (EDCs) in the polychaete Paraprionospio sp. from the Yodo River mouth, Osaka Bay, Japan.

    PubMed

    Nurulnadia, Mohd Yusoff; Koyama, Jiro; Uno, Seiichi; Kito, Asami; Kokushi, Emiko; Bacolod, Eugene Tan; Ito, Kazuki; Chuman, Yasutaka

    2014-03-01

    This study presents the levels of endocrine disrupting chemicals (EDCs) accumulated by Paraprionospio sp. from the Yodo River mouth, Osaka Bay. Since high concentrations of nonylphenol (NP), bisphenol A (BP), octylphenol (OP), 17β-estradiol (E2), and estrone (E1) have been measured in sediment from Osaka Bay, some bioaccumulation could be expected particularly in benthic animals. EDCs were analysed in Paraprionospio sp., a dominant benthic species in Osaka Bay. The results showed that Paraprionospio sp. had accumulated varying concentrations (wet weight; w.w.) of NP at 1,460-4,410 ng/g; BP at 22.5-39.6 ng/g; OP at 18.9-45.4 ng/g; E2 at 0.89-4.35 ng/g; and E1 at 0.06-2.50 ng/g. Accumulation of NP and OP were highest among the samples gathered in summer (July 2008), while concentrations of BP, E2, and E1 did not much differs within 3 years. EDC levels in Paraprionospio sp. were apparently greater than those in sediments showing bioaccumulation.

  19. High-resolution modeling and evaluation of ozone air quality of Osaka using MM5-CMAQ system.

    PubMed

    Shrestha, Kundan Lal; Kondo, Akira; Kaga, Akikazu; Inoue, Yoshio

    2009-01-01

    High-resolution modeling approach is increasingly being considered as a necessary step for improving the monitoring and predictions of regional air quality. This is especially true for highly urbanized region with complex terrain and land-use. This study uses Community Multiscale Air Quality (CMAQ) model coupled with MM5 mesoscale model for a comprehensive analysis to assess the suitability of such high-resolution modeling system in predicting ozone air quality in the complex terrains of Osaka, Japan. The 1-km and 3-km grid domains were nested inside a 9-km domain and the domain with 1-km grid covered the Osaka region. High-resolution Grid Point Value-Mesoscale Model (GPV-MSM) data were used after suitable validation. The simulated ozone concentrations were validated and evaluated using statistical metrics using performance criteria set for ozone. Daily maxima of ozone were found better simulated by the 1-km grid domain than the coarser 9-km and 3-km domains, with the maximum improvement in the mean absolute gross error about 3 ppbv. In addition, 1-km grid results fared better than other grids at most of the observation stations that showed noticeable differences in gross error as well as correlation. These results amply justify the use of the integrated high-resolution MMS-CMAQ modeling system in the highly urbanized region, such as the Osaka region, which has complex terrain and land-use.

  20. Sulfate reduction and sulfide oxidation in anoxic confined aquifers in the northeastern Osaka Basin, Japan

    NASA Astrophysics Data System (ADS)

    Yamanaka, Masaru; Nakano, Takanori; Tase, Norio

    2007-03-01

    SummaryWe used δ 34S values and chemical compositions of groundwater to investigate the influence of sulfate reduction and sulfide oxidation processes in a confined aquifer system in the northeastern Osaka Basin (NEOB), central Japan. Shallow confined groundwater (<100 m) in the basin is recharged mainly from mountainous areas to the north, and flows south and southwest through the aquifer system. Anion composition of the groundwater is dominated by HCO3- throughout the basin. However, concentrations of redox-sensitive species such as dissolved oxygen, NO3-, Fe 2+, and Mn 2+ show that groundwater conditions become increasingly anoxic along the flowpaths. Moreover, SO 4/(SO 4 + 2HCO 3) molar ratios decrease with increasing δ 34S along the flowpaths, which demonstrates that sulfate is reduced in the NEOB aquifer system. Groundwater with both high total dissolved solids and high SO 4 content was observed mainly in areas down-flow from faults. Because of the high SO 4 content, the anion composition of this groundwater cannot be adequately explained by a simple sulfate reduction process. A Rayleigh distillation model with ɛ = -20‰, which allows for sulfide oxidation within marine sediments in proximity to faults, explains the chemistry of all groundwater samples, including those with high SO 4 content. The model demonstrates that 76% of initial sulfate is reduced at maximum, and that reduced SO42- content is up to 48.5 mg/L after sulfide oxidation in the NEOB aquifer system.

  1. Consumer attitudes to radiation and irradiated potatoes at ``Radiation Fair'' in Osaka, Japan

    NASA Astrophysics Data System (ADS)

    Furuta, Masakazu; Hayashi, Toshio; Hosokawa, Yasushi; Kakefu, Tomohisa; Nishihara, Hideaki

    1998-06-01

    "Radiation Fair" has been held in summer vacation season in August for more than 10 years in Osaka, the largest city of western Japan, for the purpose of public education and information transfer of radiation and radiation-related technology. We distributed questionnaires to the visitors for recent 3 years to inquire their status toward radiation and irradiated products including irradiated potatoes as well as impression toward the displays. According to the survey results, more than 60% of the kids visitors were satisfied with this exhibition as informative, more than half of the older visitors (16 years old and upward) indicated that they recognized the word of "radiation" when they were at elementary school and the most significant sources of this information were school lessons and the mass media. Consumer's image toward radiation seems to shift to more "positive" when correct knowledge about radiation is given. More than half of consumers did not know "irradiated potatoes" but the percentage indicating that irradiated potatoes was definitely hazardous was less than 10%.

  2. Epidemics of GI.2 sapovirus in gastroenteritis outbreaks during 2012-2013 in Osaka City, Japan.

    PubMed

    Iritani, Nobuhiro; Yamamoto, Seiji P; Abe, Niichiro; Kubo, Hideyuki; Oka, Tomoichiro; Kaida, Atsushi

    2016-07-01

    Sapovirus (SaV) is a causative agent of gastroenteritis in humans in both sporadic cases and outbreaks. During the period from January 2005 to August 2014, SaV was detected in 30 (5.9%) of 510 gastroenteritis outbreaks in Osaka City, Japan using real-time RT-PCR. Seasonal distribution of SaV-associated outbreaks revealed an increase during the 2011-2012 season and the highest frequency of outbreaks during the 2012-2013 season. Genotyping analysis based on the capsid region demonstrated that the most common genotype was GI.2 (36.7%), in which the strains were closely related. The comparison of complete capsid gene sequences with 18 GI.2 strains (7 strains in this study and 11 from GenBank) between 1990 and 2013 showed that GI.2 strains were classified into at least three genetic clusters (1990-2000, 2004-2007, and 2008-2013) with chronologically unique amino acid residues and accumulation of mutations in the predicted P domain, suggesting the one of the causes of emergence and spread of GI.2 strains. This study will also be helpful for understanding the evolutionary mechanism of the SaV genome. © 2015 Wiley Periodicals, Inc.

  3. Analysis of colors used on outdoor advertising in urban landscape: a case study in Osaka city

    NASA Astrophysics Data System (ADS)

    Takahashi, Mika; Fujibayashi, Kazumi; Shimonaka, Tomomi; Sato, Masako; Sawa, Kazuhiro

    2002-06-01

    This is a case study for practical survey and assessment of urban landscapes containing outdoor advertisements in Osaka City, Japan. We practically surveyed and analyzed the colors used on the outdoor advertisements in the three urban areas: the business area long the main street, the amusement area along the shopping street, and the station plaza in front of the railroad terminal. Further by the laboratory experiments, we examined the interrelation between the atmosphere of the area and the impression arising from the outdoor advertisements using the pictures of street scenes on video monitor. In this experiment, eye movements of each subject observing the scene were analyzed by eye point recorder. (1) In general, vivid red, yellow, green and blue, and white and black were frequently used on the outdoor advertisements in every area. (2) The character of each area was respectively found out by analysis of the following factors: the type of advertisement, the size of each advertisement, and the arrangement of the advertisements. Vivid colors on the outdoor advertisements could be clearly perceived even from a distance. Then, our eyes would be attracted by vivid colors of them. (4) The atmosphere of the area would be affected by favorable or unfavorable impression from the outdoor advertisements. For instance, on the main street, the advertisements would impress us favorably if they are in harmony with each other and create an orderly and elegant streetscape. On the shopping street, various advertisements would impress us favorably if they create a lively and cheerful streetscape.

  4. A manikin-based observational study on cardiopulmonary resuscitation skills at the Osaka Senri medical rally.

    PubMed

    Kobayashi, Masanao; Fujiwara, Akira; Morita, Hiroshi; Nishimoto, Yasuhisa; Mishima, Takayuki; Nitta, Masahiko; Hayashi, Toshimasa; Hotta, Toshihiro; Hayashi, Yasuyuki; Hachisuka, Eisou; Sato, Kenji

    2008-09-01

    To examine the current status and problems of resuscitation management in Japan as demonstrated at the 2006 and 2007 Osaka Senri medical rallies. Using manikins, the quality of resuscitation was evaluated in 33 teams that participated in the medical rallies. The challenge was to deliver defibrillation shocks for ventricular fibrillation; data were recorded using the Laerdal PC Skill Reporting System (Norway). The teams were first subjectively (visually) evaluated by a panel of judges and these evaluations were later reaffirmed using video records. An approximately 30s delay was observed between the time of contact and initiation of chest compression in the teams that adopted the American Heart Association (AHA) method compared with those that adopted the European Resuscitation Council (ERC) method. Although the overall quality of chest compressions was very good, in several instances, the hand positions were inappropriate and complete chest recoil was not achieved. The left paddle was incorrectly positioned by all teams. Only 15.8% of the teams were able to deliver shocks with less than 10s of interruption between the chest compressions. Regarding interruption of chest compressions at confirmation of correct tracheal tube placement, among the eight teams that adopted the AHA method, pauses of more than 10s were confirmed in five (62.5%). Significant differences in performance between the AHA and ERC methods were observed. The ERC guidelines were more rational and suitable in terms of actual application than the AHA guidelines.

  5. [Occupational health of endoscope sterilization workers in medical institutions in Osaka Prefecture].

    PubMed

    Miyajima, Keiko; Tabuchi, Takeo; Kumagai, Shinji

    2006-09-01

    To clarify the actual condition of endoscope sterilization work and the adverse health effects of disinfectants on personnel, a questionnaire was sent to 173 medical institutions in Osaka Prefecture. Glutaraldehyde (GA), ortho-phtalaldehyde (OPA), and hyperacetic acid were used as disinfectants of endoscopes by 55.5%, 32.4%, and 8.7% of the medical institutions respectively. The kind of disinfectant used had been changed in 57.8% of these institutions during the past five years, and it was confirmed that the use of substitutes for GA, such as OPA and hyperacetic acid, has increased. Personnel in 35.8% of the institutions complained about symptoms during sterilization work. The kind of disinfectant being used when they complained was GA in many cases and OPA in others. A general ventilation system has now been installed in 72.3% of the institutions; local exhaust systems have been installed in fewer, only 23.4%. Protective gloves were used at about half of the institutions, but protective masks and glasses were seldom used. This study shows that the occupational health problems of endoscope sterilization work have not been resolved. Consequently, it is necessary to promote the installation of ventilation systems and the use of protective devices in all institutions. Health education in regard to the handling of disinfectants is also necessary. Because little information is available about the toxic effects of OPA and hyperacetic acid, epidemiological studies must be conducted to clarify the human health effect of these disinfectants.

  6. DuraHeart™ magnetically levitated left ventricular assist device: Osaka University experience.

    PubMed

    Sakaguchi, Taichi; Matsumiya, Goro; Yoshioka, Daisuke; Miyagawa, Shigeru; Nishi, Hiroyuki; Yoshikawa, Yasushi; Fukushima, Satsuki; Saito, Shunsuke; Ueno, Takayoshi; Sawa, Yoshiki

    2013-01-01

    The DuraHeart left ventricular assist device (LVAD) is the world's first approved magnetically levitated implantable centrifugal pump. We report our initial experience with the DuraHeart as a bridge to heart transplantation. Between 2008 and 2011, 23 patients (17 males; mean age 35 years, range 16-53 years) with endstage heart failure underwent implantation with the DuraHeart LVAD at Osaka University Hospital. Of those, 7 underwent conversion surgery from a Nipro paracorporeal LVAD to the DuraHeart. There were no deaths during the mean support period of 559±241 days (176-999 days). In total, 17 patients (74%) remain with the LVAD and 5 (22%) underwent heart transplantation after 580±302 days (176-982 days) of support. Major adverse events included 8 (34%) driveline/pocket infections, 4 (17%) cerebrovascular accidents, 4 (17%) right heart failures requiring mechanical support, and 3 (13%) mechanical device failures (magnetic levitation failure caused by driveline fracture). Of the 5 patients who developed pump pocket infection, 3 underwent previous conversion surgery from the Nipro LVAD. Our initial experience with the DuraHeart LVAD in Japan demonstrated excellent long-term survival with acceptable rates of adverse events. With refinement of the system, including mechanical durability, this pump will further enhance the quality of life for patients who require long-term mechanical circulatory support.

  7. An overview of multidisciplinary research resources at the Osaka University Center for Twin Research.

    PubMed

    Hayakawa, Kazuo; Iwatani, Yoshinori

    2013-02-01

    Osaka University Center for Twin Research is currently organizing a government-funded, multidisciplinary research project using a large registry of aged twins living in Japan. The purpose of the project is to collect various information as well as biological resources from registered twins, and to establish a biobank and databases for preserving and managing these data and resources. The Center is collecting data from twin pairs, both of whom have agreed to participate in a one-day comprehensive medical examination. The following data are being collected: physical data (e.g., height, body mass, blood pressure, theoretical visceral fat, pulse wave velocity, and bone density), data regarding epidemiology (e.g., medical history, lifestyle, quality of life, mood status, cognitive function, and nutrition), electrocardiogram, ultrasonography (carotid artery and thyroid), dentistry, plastic surgery, positron emission tomography, magnetoencephalogram, and magnetic resonance imaging of brain. These data are then aggregated and systematically stored in specific databases. In addition, peripheral blood is obtained from the participants, and then genomic DNA is purified and sera are stored. A wide variety of studies are ongoing, and more are in the planning stage.

  8. Study on EUV emission properties of laser-produced plasma at ILE, Osaka

    NASA Astrophysics Data System (ADS)

    Nakai, Mitsuo; Nishimura, Hiroaki; Shigemori, Keisuke; Miyanaga, Noriaki; Norimatsu, Takayoshi; Nagai, Keiji; Matsui, Ryoji; Hibino, Takehiro; Okuno, Tomoharu; Sohbatzadeh, F. S.; Tao, Y.; Hashimoto, Kazuhisa; Yamaura, Michiteru; Fujioka, Shinsuke; Nagatomo, Hideo; Zhakhovskii, Vasilii; Nishihara, Katsunobu; Uchida, Shigeaki; Shimada, Yoshinori; Furukawa, Hiroyuki; Nakatsuka, Masahiro; Izawa, Yasukazu

    2004-01-01

    A new research project on extreme ultraviolet (EUV) source development has just been started at the Institute of Laser Engineering, Osaka University. The main task of this project is to find a scientific basis for generating efficient, high-quality, high power EUV plasma source for semiconductor industry. A set of experimental data is to be provided to develop a detailed atomic model included in computer code through experiments using GEKKO-XII high power laser and smaller but high-repetitive lasers. Optimum conditions for efficient EUV generation will be investigated by changing properties of lasers and targets. As the first step of the experiments, spherical solid tin and tin-oxide targets were illuminated uniformly with twelve beams from the GEKKO XII. It has been confirmed that maximum conversion efficiency into 13.5 nm EUV light is achieved at illumination intensity less than 2 x 1011 W/cm2. No significant difference is found between laser wavelengths of one μm and a half μm. Density structure of the laser-irradiated surface of a planar tin target has beem measured experimentally at 1012 W/cm2 to show formation of double ablation structure with density plateau by thermal radiation transport. An opacity experiment has just been initiated.

  9. Modelling of wave propagation and attenuation in the Osaka sedimentary basin, western Japan, during the 2013 Awaji Island earthquake

    NASA Astrophysics Data System (ADS)

    Asano, Kimiyuki; Sekiguchi, Haruko; Iwata, Tomotaka; Yoshimi, Masayuki; Hayashida, Takumi; Saomoto, Hidetaka; Horikawa, Haruo

    2016-03-01

    On 2013 April 13, an inland earthquake of Mw 5.8 occurred in Awaji Island, which forms the western boundary of the Osaka sedimentary basin in western Japan. The strong ground motion data were collected from more than 100 stations within the basin and it was found that in the Osaka Plain, the pseudo velocity response spectra at a period of around 6.5 s were significantly larger than at other stations of similar epicentral distance outside the basin. The ground motion lasted longer than 3 min in the Osaka Plain where its bedrock depth spatially varies from approximately 1 to 2 km. We modelled long-period (higher than 2 s) ground motions excited by this earthquake, using the finite difference method assuming a point source, to validate the present velocity structure model and to obtain better constraint of the attenuation factor of the sedimentary part of the basin. The effect of attenuation in the simulation was included in the form of Q(f) = Q0(f/f0), where Q0 at a reference frequency f0 was given by a function of the S-wave velocity, Q0 = αVS. We searched for appropriate Q0 values by changing α for a fixed value of f0 = 0.2 Hz. It was found that values of α from 0.2 to 0.5 fitted the observations reasonably well, but that the value of α = 0.3 performed best. Good agreement between the observed and simulated velocity waveforms was obtained for most stations within the Osaka Basin in terms of both amplitude and ground motion duration. However, underestimation of the pseudo velocity response spectra in the period range of 5-7 s was recognized in the central part of the Osaka Plain, which was caused by the inadequate modelling of later phases or wave packets in this period range observed approximately 2 min after the direct S-wave arrival. We analysed this observed later phase and concluded that it was a Love wave originating from the direction of the east coast of Awaji Island.

  10. Associations between Subjective Happiness and Dry Eye Disease: A New Perspective from the Osaka Study

    PubMed Central

    Kawashima, Motoko; Uchino, Miki; Yokoi, Norihiko; Uchino, Yuichi; Dogru, Murat; Komuro, Aoi; Sonomura, Yukiko; Kato, Hiroaki; Kinoshita, Shigeru; Mimura, Masaru; Tsubota, Kazuo

    2015-01-01

    Importance Dry eye disease has become an important health problem. A lack of concordance between self-reported symptoms and the outcome of dry eye examinations has raised questions about dry eye disease. Objective To explore the association between subjective happiness and objective and subjective symptoms of dry eye disease. Design The study adopted a cross-sectional design. Setting All the employees of a company in Osaka, Japan. Participants 672 Japanese office workers using Visual Display Terminals (age range: 26–64 years). Methods The dry eye measurement tools included the Schirmer test, conjunctivocorneal staining, the tear film break-up time, as well as the administration of a dry eye symptoms questionnaire. Happiness was measured by the Subjective Happiness Scale. Main Outcome Measures Dry eye examination parameters, dry eye symptoms questionnaires, and the Subjective Happiness Scale score. Results Of the 672 workers, 561 (83.5%) completed the questionnaires and examinations. The mean Subjective Happiness Scale score was 4.91 (SD = 1.01). This score was inversely correlated with the dry eye symptom score (r = -0.188, p < 0.001), but was not associated with objective findings which include conjunctivocorneal staining, low Schirmer test score, or low tear film break-up time. The level of subjective happiness was the lowest in the group without objective results, but reported subjective symptoms of dry eyes (p < 0.05). Conclusions and Relevance There is evidence of the relationship between subjective happiness and self-reported symptoms of dry eyes. Findings of this study revealed a new perspective on dry eye disease, including the potential for innovative treatments of a specific population with dry eye disease. PMID:25830665

  11. Associations between subjective happiness and dry eye disease: a new perspective from the Osaka study.

    PubMed

    Kawashima, Motoko; Uchino, Miki; Yokoi, Norihiko; Uchino, Yuichi; Dogru, Murat; Komuro, Aoi; Sonomura, Yukiko; Kato, Hiroaki; Kinoshita, Shigeru; Mimura, Masaru; Tsubota, Kazuo

    2015-01-01

    Dry eye disease has become an important health problem. A lack of concordance between self-reported symptoms and the outcome of dry eye examinations has raised questions about dry eye disease. To explore the association between subjective happiness and objective and subjective symptoms of dry eye disease. The study adopted a cross-sectional design. All the employees of a company in Osaka, Japan. 672 Japanese office workers using Visual Display Terminals (age range: 26-64 years). The dry eye measurement tools included the Schirmer test, conjunctivocorneal staining, the tear film break-up time, as well as the administration of a dry eye symptoms questionnaire. Happiness was measured by the Subjective Happiness Scale. Dry eye examination parameters, dry eye symptoms questionnaires, and the Subjective Happiness Scale score. Of the 672 workers, 561 (83.5%) completed the questionnaires and examinations. The mean Subjective Happiness Scale score was 4.91 (SD = 1.01). This score was inversely correlated with the dry eye symptom score (r = -0.188, p < 0.001), but was not associated with objective findings which include conjunctivocorneal staining, low Schirmer test score, or low tear film break-up time. The level of subjective happiness was the lowest in the group without objective results, but reported subjective symptoms of dry eyes (p < 0.05). There is evidence of the relationship between subjective happiness and self-reported symptoms of dry eyes. Findings of this study revealed a new perspective on dry eye disease, including the potential for innovative treatments of a specific population with dry eye disease.

  12. Predictive factors of Osaka Medical College (OMC) brace treatment in patients with adolescent idiopathic scoliosis.

    PubMed

    Kuroki, Hiroshi; Inomata, Naoki; Hamanaka, Hideaki; Higa, Kiyoshi; Chosa, Etsuo; Tajima, Naoya

    2015-01-01

    Factors influencing clinical course of brace treatment apply to adolescent idiopathic scoliosis (AIS) patients remain unclear. By making clear them, we may select suitable patients for brace treatment and alleviate overtreatment. The purpose of this study was to explore predictive factors of Osaka Medical College (OMC) brace treatment for AIS patients in accordance with the modified standardized criteria proposed by the Scoliosis Research Society (SRS) committee on bracing and non-operative management. From 1999 through 2010, 31 consecutive patients with AIS who were newly prescribed the OMC brace and met the modified SRS criteria were studied. The study included 2 boys and 29 girls with a mean age of 12 years and 0 month. We investigated the clinical course and evaluated the impacts of compliance, initial brace correction rate, curve flexibility, curve pattern, Cobb angle, chronological age, and Risser stage to clinical outcomes. The clinical course of the brace treatment was considered progression if ≥6° curvature increase occurred and improvement if ≥6° curvature decrease occurred according to SRS judgment criteria. The curve progressed in 10 cases, the curve improved in 6 cases, and the curve remained unchanged in 15 cases (success rate: 67.7%). The success rate was statistically higher in the patient group whose instruction adherence rate was greater than 50% as compared with in those 50% or less. Initial brace correction rate, curve flexibility, curve pattern, the magnitude of Cobb angle, chronological age, and Risser stage did not have any significant effect for clinical courses. However, success rate was insignificantly higher in the cases whose Cobb angle in brace was smaller than that in hanging position. OMC brace treatment could alter the natural history of AIS, however, that was significantly affected by compliance of brace wear.

  13. Regional Survey of Tissue Donation Among the General Public and Medical Staffs Around Osaka, Japan.

    PubMed

    Ogawa, M; Fujita, T; Fukushima, N; Nakatani, T; Kitamiura, S; Imamura, Y; Watanabe, K; Iwata, S; Kinjo, A

    2016-09-01

    Because tissue transplantation (TTx) has not been familiar to the general public or even to medical staffs in Japan, awareness of TTx is very important to increase tissue donation. Our primary aim was to describe the current status of awareness of TTx in medical staffs and in the general public around Osaka. Between July 2014 and February 2015, 1015 general public citizens, 203 medical staff members working in emergency hospitals, and 168 cardiothoracic surgeons were invited to complete a letter or web-based survey through the use of a self-designed questionnaire. In the general public citizens, only 25.1% knew about TTx, whereas 54.7% knew about organ transplantation (OTx); 25.4% agreed to donate their organs or tissues and 17.3% disagreed to donate their organs or tissues. In medical staff members working in emergency hospitals, 58.7% knew about TTx; 82.3% agreed to support organ or tissue procurement and 10.8% disagreed to do so. Among cardiothoracic surgeons, 78.7% knew about TTx; 33.2% had used valve or vascular homografts and 57.4% wanted to use them if possible. According to these surveys, public awareness of TTx has been less than that of OTx, but willingness to donate tissue was not different from that of donating organs. Awareness of TTx in medical staffs in emergency hospitals was higher but still not satisfactory. To increase tissue donation in Japan, the East and West Japan Tissue Transplant Network, in collaboration with cardiothoracic surgeons, should make more effort to carry out dissemination and awareness regarding TTx to the general public and to medical staffs. Copyright © 2016 Elsevier Inc. All rights reserved.

  14. Screening for hereditary angioedema (HAE) at 13 emergency centers in Osaka, Japan: A prospective observational study.

    PubMed

    Hirose, Tomoya; Kimbara, Futoshi; Shinozaki, Masahiro; Mizushima, Yasuaki; Yamamoto, Hidehiko; Kishi, Masashi; Kiguchi, Takeyuki; Shiono, Shigeru; Noborio, Mitsuhiro; Fuke, Akihiro; Akimoto, Hiroshi; Kimura, Takaaki; Kaga, Shinichiro; Horiuchi, Takahiko; Shimazu, Takeshi

    2017-02-01

    Hereditary angioedema (HAE) with deficiency of C1 inhibitor (C1-INH) is an autosomal-dominant disease characterized by recurrent episodes of potentially life-threatening angioedema. The objective is to study the incidence of HAE among patients who visit the emergency department.This was a 3-year prospective observational screening study involving 13 urban tertiary emergency centers in Osaka prefecture, Japan. Patients were included if they met the following criteria: unexplained edema of the body, upper airway obstruction accompanied by edema, anaphylaxis, acute abdomen with intestinal edema (including ileus and acute pancreatitis), or asthma attack. C1-INH activity and C4 level were measured at the time of emergency department admission during the period between July 2011 and June 2014.This study comprised 66 patients with a median age of 54.0 (IQR: 37.5-68.3) years. Three patients were newly diagnosed as having HAE, and 1 patient had already been diagnosed as having HAE. C1-INH activity levels of the patients with HAE were below the detection limit (<25%), whereas those of non-HAE patients (n = 62) were 106% (IQR: 85.5%-127.0%) (normal range, 70%-130%). The median level of C4 was significantly lower in the patients with HAE compared with those without HAE (1.2 [IQR: 1-3] mg/dL vs 22 [IQR: 16.5-29.5] mg/dL, P < 0.01) (normal range, 17-45 mg/dL).Three patients with undiagnosed HAE were diagnosed as having HAE in the emergency department during the 3-year period. If patients have signs and symptoms suspicious of HAE, the levels of C1-INH activity and C4 should be measured.

  15. Clinical and endocrinological characteristics of adrenal incidentaloma in Osaka region, Japan.

    PubMed

    Tabuchi, Yukiko; Otsuki, Michio; Kasayama, Soji; Kosugi, Keisuke; Hashimoto, Kunihiko; Yamamoto, Tsunehiko; Tsugawa, Mamiko; Mineo, Ikuo; Yamada, Yuya; Kurebayashi, Shogo; Ohashi, Makoto; Umayahara, Yutaka; Kouhara, Haruhiko; Nakamura, Tadashi; Taki, Hideki; Matsuoka, Taka-Aki; Imagawa, Akihisa; Funahashi, Tohru; Shimomura, Iichiro

    2016-01-01

    The aim of this study was to investigate the clinical and endocrinological characteristics of adrenal incidentalomas in Osaka region, Japan. The study was a multicenter retrospective analysis of 150 patients with adrenal incidentalomas who underwent radiographic and endocrine evaluations between 2005 and 2013. Most adrenal incidentalomas were discovered by computed tomography (77.0%) and the rest were identified by abdominal ultrasonography (14.6%), magnetic resonance imaging (4.2%), or positron emission tomography (4.2%). Adrenal incidentalomas were more frequently localized on the left side than on the right. The average diameter of tumors was 21 ± 11 mm. On endocrinological evaluation, 14 patients were diagnosed with primary aldosteronism (9.3%), 10 with subclinical Cushing's syndrome (6.7%), 7 with pheochromocytoma (4.7%), 7 with Cushing's syndrome (4.7%), 2 with both subclinical Cushing's syndrome and primary aldosteronism (1.3%), and 110 with non-functioning tumors (73.3%). Patients with functioning tumors were significantly younger and had larger tumor diameters than those with non-functioning tumors. Except for hypertension, complications were comparable between patients with functioning and non-functioning tumors, including the presence of glucose intolerance, cardiovascular disease, and dyslipidemia. In conclusion, a higher prevalence of primary aldosteronism was observed compared with a previous report. Complications were comparable between patients with functioning and non-functioning tumors, including the frequencies of glucose intolerance, cardiovascular disease, and dyslipidemia. Long-term follow-up is required in patients with non-functioning tumors because the frequency of complications, such as glucose intolerance, cardiovascular disease, and dyslipidemia, was equal to that in patients with functioning tumors.

  16. Screening for hereditary angioedema (HAE) at 13 emergency centers in Osaka, Japan

    PubMed Central

    Hirose, Tomoya; Kimbara, Futoshi; Shinozaki, Masahiro; Mizushima, Yasuaki; Yamamoto, Hidehiko; Kishi, Masashi; Kiguchi, Takeyuki; Shiono, Shigeru; Noborio, Mitsuhiro; Fuke, Akihiro; Akimoto, Hiroshi; Kimura, Takaaki; Kaga, Shinichiro; Horiuchi, Takahiko; Shimazu, Takeshi

    2017-01-01

    Abstract Hereditary angioedema (HAE) with deficiency of C1 inhibitor (C1-INH) is an autosomal-dominant disease characterized by recurrent episodes of potentially life-threatening angioedema. The objective is to study the incidence of HAE among patients who visit the emergency department. This was a 3-year prospective observational screening study involving 13 urban tertiary emergency centers in Osaka prefecture, Japan. Patients were included if they met the following criteria: unexplained edema of the body, upper airway obstruction accompanied by edema, anaphylaxis, acute abdomen with intestinal edema (including ileus and acute pancreatitis), or asthma attack. C1-INH activity and C4 level were measured at the time of emergency department admission during the period between July 2011 and June 2014. This study comprised 66 patients with a median age of 54.0 (IQR: 37.5–68.3) years. Three patients were newly diagnosed as having HAE, and 1 patient had already been diagnosed as having HAE. C1-INH activity levels of the patients with HAE were below the detection limit (<25%), whereas those of non-HAE patients (n = 62) were 106% (IQR: 85.5%–127.0%) (normal range, 70%–130%). The median level of C4 was significantly lower in the patients with HAE compared with those without HAE (1.2 [IQR: 1–3] mg/dL vs 22 [IQR: 16.5–29.5] mg/dL, P < 0.01) (normal range, 17–45 mg/dL). Three patients with undiagnosed HAE were diagnosed as having HAE in the emergency department during the 3-year period. If patients have signs and symptoms suspicious of HAE, the levels of C1-INH activity and C4 should be measured. PMID:28178173

  17. Increase of GII.2 norovirus infections during the 2009-2010 season in Osaka City, Japan.

    PubMed

    Iritani, Nobuhiro; Kaida, Atsushi; Abe, Niichiro; Sekiguchi, Jun-Ichiro; Kubo, Hideyuki; Takakura, Koh-Ichi; Goto, Kaoru; Ogura, Hisashi; Seto, Yoshiyuki

    2012-03-01

    During the 2009-2010 season, a significant numerical increase of genotype GII.2 norovirus (NoV)-associated outbreaks was observed in Osaka City, Japan. The most common genotype in that season was GII.2 (44.6%), followed by GII.4 (39.2%). Mostly, GII.2 strains were associated with outbreaks in children and with person-to-person contact. The National Infectious Disease Surveillance Center reported that GII.2 NoV infections were widespread in Japan in that season. Comparative phylogenetic analysis of RNA-dependent RNA polymerase (RdRp) and capsid sequences revealed that this GII.2 epidemic resulted from two genetic strains. The first, GII.2p2 strains, had an identical genotype in the RdRp and capsid genes. GII.2p2 strains in the 2009-2010 season were a different genetic cluster from the strains of spring 2004, the previous epidemic of GII.2 NoV, but showed no unique amino acid change. The second, GII.2 chimera virus (GII.2p16), had GII.16 RdRp and GII.2 capsid genotypes, suggesting prior recombination at the junction of ORF1 and ORF2. GII.2p16 strains had four significant amino acid changes in the P2 subdomain, suggesting antigenic changes. Before the 2009-2010 season, GII.2 chimera viruses had been observed only sporadically. This spreading of GII.2p16 strains in the 2009-2010 season might be the first epidemic of GII.2 chimera virus. This study revealed that the NoV epidemic in the 2009-2010 season differed considerably from the prior season, when GII.4 was predominant. Furthermore, GII.2 strains persisted in human populations by drastic recombination and gradual accumulation of mutations, indicating a prevalent pattern of non-GII.4 genotypes with genetic evolution.

  18. Modeling of Wave Propagation in the Osaka Sedimentary Basin during the 2013 Awaji Island Earthquake (Mw5.8)

    NASA Astrophysics Data System (ADS)

    Asano, K.; Sekiguchi, H.; Iwata, T.; Yoshimi, M.; Hayashida, T.; Saomoto, H.; Horikawa, H.

    2013-12-01

    The three-dimensional velocity structure model for the Osaka sedimentary basin, southwest Japan is developed and improved based on many kinds of geophysical explorations for decades (e.g., Kagawa et al., 1993; Horikawa et al., 2003; Iwata et al., 2008). Recently, our project (Sekiguchi et al., 2013) developed a new three-dimensional velocity model for strong motion prediction of the Uemachi fault earthquake in the Osaka basin considering both geophysical and geological information by adding newly obtained exploration data such as reflection surveys, microtremor surveys, and receiver function analysis (hereafter we call UMC2013 model) . On April 13, 2013, an inland earthquake of Mw5.8 occurred in Awaji Island, which is close to the southwestern boundary of the aftershock area of the 1995 Kobe earthquake. The strong ground motions are densely observed at more than 100 stations in the basin. The ground motion lasted longer than four minutes in the Osaka urban area where its bedrock depth is about 1-2 km. This long-duration ground motions are mainly due to the surface waves excited in this sedimentary basin whereas the magnitude of this earthquake is moderate and the rupture duration is expected to be less than 5 s. In this study, we modeled long-period (more than 2s) ground motions during this earthquake to check the performance of the present UMC2013 model and to obtain a better constraint on the attenuation factor of sedimentary part of the basin. The seismic wave propagation in the region including the source and the Osaka basin is modeled by the finite difference method using the staggered grid solving the elasto-dynamic equations. The domain of 90km×85km×25.5km is modeled and discretized with a grid spacing of 50 m. Since the minimum S-wave velocity of the UMC2013 model is about 250 m/s, this calculation is valid up to the period of about 1 s. The effect of attenuation is included in the form of Q(f)=Q0(T0/T) proposed by Graves (1996). A PML is implemented in

  19. Surface wave group velocity in the Osaka sedimentary basin, Japan, estimated using ambient noise cross-correlation functions

    NASA Astrophysics Data System (ADS)

    Asano, Kimiyuki; Iwata, Tomotaka; Sekiguchi, Haruko; Somei, Kazuhiro; Miyakoshi, Ken; Aoi, Shin; Kunugi, Takashi

    2017-08-01

    Inter-station cross-correlation functions estimated using continuous ambient noise or microtremor records were used to extract the seismic wave propagation characteristics of the Osaka sedimentary basin, Japan. Temporary continuous observations were conducted at 15 sites in the Osaka basin between 2011 and 2013. The data were analyzed using seismic interferometry. The target period range was 2-8 s. Cross-correlations between all of the possible station pairs were calculated and stacked to produce a year-long data set, and Rayleigh wave signals in the vertical and radial components and Love wave signals in the transverse component were identified from the results. Simulation of inter-station Green's functions using the finite difference method was conducted to check the performance of the current three-dimensional velocity structure model. The measured time lag between the observed and theoretical Green's functions was less than 2 s for most station pairs, which is less than the wave period of interest in the target frequency range. Group velocity tomography was applied to group delay times estimated by means of multiple filter analysis. The estimated group velocities for longer periods of 5-8 s exhibited spatial variation within the basin, which is consistent with the bedrock depth distribution; however, the group velocities for shorter periods of 2-3 s were almost constant over the studied area. The waveform and group velocity information obtained by seismic interferometry analysis can be useful for future reconstruction of a three-dimensional velocity structure model in the Osaka basin.[Figure not available: see fulltext.

  20. Mock-up experiment at Birmingham University for BNCT project of Osaka University--Neutron flux measurement with gold foil.

    PubMed

    Tamaki, S; Sakai, M; Yoshihashi, S; Manabe, M; Zushi, N; Murata, I; Hoashi, E; Kato, I; Kuri, S; Oshiro, S; Nagasaki, M; Horiike, H

    2015-12-01

    Mock-up experiment for development of accelerator based neutron source for Osaka University BNCT project was carried out at Birmingham University, UK. In this paper, spatial distribution of neutron flux intensity was evaluated by foil activation method. Validity of the design code system was confirmed by comparing measured gold foil activities with calculations. As a result, it was found that the epi-thermal neutron beam was well collimated by our neutron moderator assembly. Also, the design accuracy was evaluated to have less than 20% error.

  1. [The equal employment opportunity that began at the pharmacy division of the Osaka Imperial University Hospital from the pre-war era of Showa].

    PubMed

    Nakamuro, K

    1993-01-01

    In 1940 when sexual discrimination prevailed in Japan because of the world war, equal sexual employment was carried out at the pharmacy division of the Osaka University through the effort of Prof. Satani (Dean), Dr. Kaneko (Assistant Superintendent of the Kobe Womens' Pharmaceutical College) and Dr. Okazaki (of the Teikoku Womens' Pharmaceutical College) and was put into practice by the Ministry of Health and Welfare by the request of the Superintendent of the Osaka University Hospital. Finally, in 1985 equal employment opportunity was brought into Japan by the instruction of GHQ.

  2. Incidence of metachronous second primary cancers in Osaka, Japan: update of analyses using population-based cancer registry data.

    PubMed

    Tabuchi, Takahiro; Ito, Yuri; Ioka, Akiko; Miyashiro, Isao; Tsukuma, Hideaki

    2012-06-01

    Cancer survivors are at excess risk of developing second primary cancers, but the precise level of risk in Japanese patients is not known. To investigate the risk of survivors developing second primary cancers, we conducted a retrospective cohort study using data from the Osaka Cancer Registry. The study subjects comprised all reported patients aged 0-79 years who were first diagnosed with cancer between 1985 and 2004 in Osaka and who survived for at least 3 months, followed-up through to December 2005. A metachronous second primary cancer was defined as any invasive second cancer that was diagnosed between 3 months and 10 years after the first cancer diagnosis. The main outcome measures were incidence rates per 100,000 person-years, cumulative risk and standardized incidence ratios (SIR) of second primary cancer. Metachronous second primary cancers developed in 13,385 of 355,966 survivors (3.8%) after a median follow-up of 2.5 years. Sex-specific incidence rates of metachronous second primary cancer per 100,000 person-years increased with age, and were higher among men than women (except for the 0-49 years age group), but these rates did not differ over the study period. The 10-year cumulative risk was estimated as 13.0% for those who first developed cancer at 60-69 years of age (16.2% for men, 8.6% for women). The SIR among those with first cancer diagnosed at 0-39 and 40-49 years of age were 2.13 and 1.52, respectively, in both sexes, whereas the SIR among cancers of the mouth/pharynx, esophagus and larynx were much higher than one as for site relationships. We showed that cancer survivors in Osaka, Japan, were at higher risk of second primary cancers compared with the general population. Our findings indicate that second primary cancers should be considered as a commonly encountered major medical problem. Further investigations are required to advance our understanding to enable the development of effective measures against multiple primary cancers. © 2012

  3. Role of age and tumour stage in the temporal pattern of 'cure' from stomach cancer: a population-based study in Osaka, Japan.

    PubMed

    Ito, Yuri; Nakayama, Tomio; Tsukuma, Hideaki; Miyashiro, Isao; Ioka, Akiko; Sugimoto, Tomoyuki; Rachet, Bernard

    2012-04-01

    To evaluate progress in stomach cancer care in Japan since 1975. Population-based study of data extracted from the Osaka Cancer Registry. Population-based cancer registry in the area of Osaka Prefecture. All 66,032 cases diagnosed with a stomach cancer in Osaka Prefecture, Japan between 1975 and 2000 and registered in the Osaka Cancer Registry. 'Cure' fraction and median survival time for 'uncured' patients were estimated with multivariable mixture 'cure' model. The role played by age and stage at diagnosis on the changes in 'cure' parameters between 1975 and 2000 was evaluated. Missing stage was handled by multiple imputation approach. More than 50% of the patients diagnosed with a stomach cancer in 1996-2000 were estimated 'cured' from their cancer, corresponding to a 20% increase since 1975-1980. Median survival time for 'uncured' patients however remained unchanged at about 8 months. 'Cure' fraction was over 85% for localised tumours and 30% for regional tumours, but stayed as low as 2.5% for distant metastatic cancers. Improvement was underestimated by about 10% because of ageing of cancer patients. Changes in stage distribution explained up to 40% of the increase in 'cure' fraction among men and up to 13% in women. Overdiagnosis was unlikely to play any role in these patterns. 'Cure' fraction from stomach cancer dramatically increased in Osaka, Japan since 1975, partly because of earlier stage at diagnosis, but mostly due to improvement in treatment of stomach cancer patients. This study, based on a leading country in term of stomach cancer management, provides insightful results for other countries in which 'cure' fraction is usually much lower. Copyright © 2012 Elsevier Ltd. All rights reserved.

  4. [A Survey of School Lunch Provision for Elementary School Students with Food Allergy in Seven Cities of Osaka Prefecture].

    PubMed

    Kiyota, Kyohei; Takemoto, Akiko; Okajima, Saori; Morino, Shizuka; Kakoi, Satoru; Sakuma, Junko; Yoshimitsu, Masato; Akutsu, Kazuhiko; Kajimura, Keiji

    2015-01-01

    The number of students with food allergy is currently increasing. Moreover, the unintentional mixing or accidental ingestion of allergy-causing food materials in school lunches has attracted great attention. The aim of this study was to verify the current status of elementary school lunch provision for students with food allergy. We investigated the elementary school lunch services in seven cities in Osaka prefecture. The egg elimination diet was provided in five of the seven cities. In four of these five cities, we did not detect the presence of egg residue either on the surface of various cookware used to prepare the egg elimination diet or in the food itself. In this investigation, the egg elimination diet was provided properly, but we observed differences among the cities in the manual preparation of foods for food allergy diets. To step up these efforts, our results suggest the necessity of preparing a manual to consider individual conditions of school lunch services.

  5. A simple method for monitoring mutagenicity of river water. Mutagens in Yodo River system, Kyoto-Osaka

    SciTech Connect

    Sakamoto, Hiroshi; Hayatsu, Hikoya )

    1990-04-01

    Blue cotton is a cotton preparation, bearing copper phthalocyanine trisulfonate as a covalently linked ligand, and is an adsorbent specific for compounds with three or greater number of fused rings. Due to this special property, blue cotton has been used for extracting mutagenic polycyclic compounds from crude materials. In early work, the authors gave a brief account of the results of monitoring river-water mutagenicity with blue cotton. Recently they have improved the quality of the adsorbent; rayon in place of cotton was employed as the support for the ligand, and a more powerful adsorbent, blue rayon, which contains 2-3 times greater amount of the ligand than blue cotton, was prepared. In this paper the authors report the use of the blue-rayon method to detect mutagenic compounds in the Yodo river, which flows through the cities of Kyoto and Osaka and is a major source of drinking water for the 10 million people in the area.

  6. The effect of long-term spatiotemporal variations in urbanization-induced eutrophication on a benthic ecosystem, Osaka Bay, Japan

    USGS Publications Warehouse

    Yasuhara, Moriaki; Yamazaki, Hideo; Tsujimoto, Akira; Hirose, K.

    2007-01-01

    Detailed spatiotemporal patterns of the influence of urbanization-induced eutrophication on a metazoan benthic community in Osaka Bay were determined using sediment cores and fossil ostracode assemblages from the last 200 yr. Results suggest that total abundance of ostracodes increased in the middle part of the bay as a result of the increase of food supply by eutrophication. Conversely, abundance decreased in the inner bay, likely because of bottom-water hypoxia by eutrophication. The variation in species composition among sites within the bay may have decreased because of the effect of eutrophication, i.e., the dominance of species that prefer food-rich environments throughout all sites. These eutrophication-induced changes occurred around 1900 as a result of Japan's industrial revolution and around 1960 as a result of rapid urbanization, depending upon location. ?? 2007, by the American Society of Limnology and Oceanography, Inc.

  7. Graduate Education Program of Design and Integration Capability at Department of Mechanical Engineering, Graduate School of Engineering, Osaka University

    NASA Astrophysics Data System (ADS)

    Fujita, Kikuo

    Department of Mechanical Engineering, Graduate School of Engineering, Osaka University is now developing “Graduate Education Program of Design and Integration Capability” under the MEXT's scheme entitled “Initiatives for Attractive Education in Graduate Schools”. Maturation of society and life, globalization of manufacturing industry, latest demands of human's welfare have changed the meaning of design from functional ensureance to value creation. This requests graduate education of mechanical engineering to turn its definition over both synthesis and analysis and to learning and communication capabilities beyond knowledge itself. With recognizing such a background, the program aims to reform the education curriculum of mechanical engineering by introducing a product design subject which integrates design methodology education and project-based learning over industry- sponsored design problems, several graduate-level fundamental subjects, and the depth area system in which elective subjects are categorized into several areas based on their specialty. This paper describes the objectives, undertakings, promises, etc. of the program.

  8. Genotyping of Norovirus strains detected in outbreaks between April 2002 and March 2003 in Osaka City, Japan.

    PubMed

    Seto, Yoshiyuki; Iritani, Nobuhiro; Kubo, Hideyuki; Kaida, Atsushi; Murakami, Tsukasa; Haruki, Kosuke; Nishio, Osamu; Ayata, Minoru; Ogura, Hisashi

    2005-01-01

    Noroviruses (NVs) are the major cause of food- and waterborne nonbacterial gastroenteritis in Japan. Between April 2002 and March 2003, a total of 111 fecal specimens from 40 outbreaks of acute nonbacterial gastroenteritis in Osaka City, Japan were subject to NV detection. Seventy-two samples (64.9%) from 31 outbreaks (77.5%) were NV positive by a real time reverse transcription (RT)-PCR assay. To further determine the genotype of individual NV strains, we sequenced the capsid N-terminal/shell (N/S) domain of some representative strains from each outbreak. The 51 NV strains detected in this study were segregated into 15 genotypes (6 in genogroup I and 9 in genogroup II), and GII/5 genotype NV was a dominant outbreak genotype.

  9. Public-access AED pad application and outcomes for out-of-hospital cardiac arrests in Osaka, Japan.

    PubMed

    Kiyohara, Kosuke; Kitamura, Tetsuhisa; Sakai, Tomohiko; Nishiyama, Chika; Nishiuchi, Tatsuya; Hayashi, Yasuyuki; Sakamoto, Tetsuya; Marukawa, Seishiro; Iwami, Taku

    2016-09-01

    Actual application of public-access automated external defibrillator (AED) pads to patients with an out-of-hospital cardiac arrest (OHCA) by the public has been poorly investigated. AED applications, prehospital characteristics, and one-month outcomes of OHCAs occurring in Osaka Prefecture from 2011 to 2012 were obtained from the Utstein Osaka Project registry. Patients with a non-traumatic OHCA occurring before emergency medical service attendance were enrolled. The proportion of AED pads that were applied to the patients' chests by the public and one-month outcomes were analysed according to the location of OHCA. In total, public-access AED pads were applied to 3.5% of OHCA patients (351/9978) during the study period. In the multivariate analyses, OHCAs that occurred in public places and received bystander-initiated cardiopulmonary resuscitation were associated with significantly higher application of public-access AEDs. Among the patients for whom public-access AED pads were applied, 29.6% (104/351) received public-access defibrillation. One-month survival with a favourable neurological outcome was significantly higher among patients who had an AED applied compared to those who did not (19.4% vs. 3.0%; OR: 2.76 [95% CI: 1.92-3.97]). The application of public-access AEDs leads to favourable outcomes after an OHCA, but utilisation of available equipment remains insufficient, and varies considerably according to the location of the OHCA event. Alongside disseminating public-access AEDs, further strategic approaches for the deployment of AEDs at the scene, as well as basic life support training for the public are required to improve survival rates after OHCAs. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  10. Diagnostic accuracy of FDG-PET cancer screening in asymptomatic individuals: use of record linkage from the Osaka Cancer Registry.

    PubMed

    Sengoku, Tami; Matsumura, Kaname; Usami, Masahisa; Takahashi, Yoshimitsu; Nakayama, Takeo

    2014-12-01

    Whole-body cancer screening with multimodalities including [(18)F]-fluorodeoxyglucose positron emission tomography (FDG-PET) detects a wide range of tumors. This program has been recognized as an option for opportunistic screening, particularly in Japan. However, reports on diagnostic accuracy have been limited. We aimed to evaluate the detectability and related properties of this screening program among asymptomatic individuals in a community setting. The study participants were 1,762 residents of Osaka Prefecture, Japan, who underwent opportunistic cancer screening at Higashitemma Clinic for the first time between November 2004 and December 2005. FDG-PET cancer screening was performed with several imaging modalities (e.g., FDG-PET, computed tomography, magnetic resonance imaging and ultrasonography) and fecal occult blood test. Screening records were linked to the Osaka cancer registry within 1 year after the screening to determine sensitivity, specificity and positive predictive values. After excluding 12 participants with cancer detected before the screening, 33 were identified by the cancer registry to have primary cancers. Of these, the present screening program found that 28 were positive (6 prostate, 5 lung, 5 colorectal, 5 thyroid, 3 liver and 4 others). Sensitivity, specificity and positive predictive values were 84.8 % (28/33, 95 % confidence interval 69.1-93.3), 86.8 % (1,491/1,718, 85.1-88.3) and 10.1 % (28/277, 6.4-12.9), respectively. FDG-PET cancer screening with multimodalities reasonably and accurately detects existing asymptomatic cancer. However, the numbers of false negatives and false positives were not insignificant. Facilities that provide the screening should inform participants of relevant information, including the limitations of this program.

  11. Tissue procurement system in Japan: the role of a tissue bank in medical center for translational research, Osaka University Hospital.

    PubMed

    Ohkawara, H; Fukushima, N; Kitagawa, T; Ito, T; Masutani, Y; Sawa, Y

    2010-01-01

    Although organ procurement has been regulated by The Organ Transplantation Law (brain-dead donors since 1997, donors after cardiac death since 1979), there has been no law or governmental procurement network (except for cornea) in Japan. Since the late 1980s, some university hospitals have developed original banks. Finally, in 2001 guidelines for tissue procurement were established by The Japanese Society of Tissue Transplantation and Japan Tissue Transplant Network (JTTN) to coordinate tissue harvesting. Five tissue banks were joined to the tissue transplant network (skin in one, heart valves in two, and bone in two). As the number of tissue banks is small, each bank cooperates on procurement, but cannot cover the entire country. With regard to skin transplantation, only one skin bank-The Japan Skin Bank Network (JSBN), which is located in Tokyo-has organized skin procurement. Therefore, it has been difficult to procure skin in areas distant from Tokyo, especially around Osaka. In order to improve such a situation, a tissue bank collaborating with the JSBN was established at The Medical Center for Translational Research (MTR), Osaka University Hospital in April 2008. The bank has played a role in skin procurement center in western Japan and supported procurement and preservation at the time of the skin procurement. Between April 2008 and September 2009, the bank participated in eight tissue procurements in the western area. In the future, the bank is planning to procure and preserve pancreatic islets and bones. Moreover, there is a plan to set up an induced pluripotent stem cells center and stem cell bank in MTR. This tissue bank may play a role to increase tissue procurement in Japan, especially in the western area. .

  12. Characteristics of ammonia gas and fine particulate ammonium from two distinct urban areas: Osaka, Japan, and Ho Chi Minh City, Vietnam.

    PubMed

    Huy, Duong Huu; Thanh, Le Tu; Hien, To Thi; Noro, Kazushi; Takenaka, Norimichi

    2017-03-01

    Continuous and simultaneous measurements of ammonia gas (NH3) and fine particulate ammonium (PM2.5NH4(+)) were performed in two distinct urban areas: Osaka, Japan, and Ho Chi Minh City (HCMC), Vietnam. Measurements were performed using a new online instrument. Two measurement periods were conducted during February 11-March 12, 2015 (cold period), and July 1-September 14, 2015 (warm period), at the urban site in Osaka, while 17 days of measurements, from May 21 to June 8, 2015, were conducted at the urban site in HCMC. The average NH3 concentration at the HCMC site was much higher than that at the Osaka site. The differences in the NH3 levels between the two cities are a result of their different emission sources. Traffic emission is a significant contributor to the NH3 levels within the urban area in Osaka. Conversely, the contribution of traffic emission to the NH3 levels in the HCMC urban area is negligible. With a population of around 8.5 million people living in the urban area of HCMC, the high NH3 level is due to human sources and poor waste management systems, especially because of the high temperature (30 °C) and dense population of the city (density up to 42,000 inhabitants per km(2)). In contrast to the NH3 levels, the highest PM2.5NH4(+) level occurred during the cold period at the Osaka site, and the average level at this site was higher than that at the HCMC site. The availability of atmospheric acids, low temperature, and high humidity facilitates the formation of ammonium. Our results indicate that NH3 plays a key role in secondary inorganic aerosol formation; therefore, it contributes to a significant amount of PM2.5 at the Osaka site. In contrast, the high levels of PM2.5 observed at the HCMC site are likely from road traffic emission, mainly motorcycles, rather than secondary inorganic aerosol formation.

  13. Long-period Ground Motion Characteristics Inside and Outside of the Osaka Basin during the 2011 Great Tohoku Earthquake and Its Largest Aftershock

    NASA Astrophysics Data System (ADS)

    Sato, K.; Iwata, T.; Asano, K.; Kubo, H.; Aoi, S.

    2013-12-01

    The 2011 great Tohoku earthquake (Mw 9.0) occurred on March 11, 2011, and the largest aftershock (Mw 7.7) at the region adjacent to south boundary of the mainshock's source region. Long-period ground motions (1-10s) of large amplitude were observed in the Osaka sedimentary basin about 550-800km away from the source regions during both events. We studied propagation and site characteristics of these ground motions, and found some common features between these two events in the Osaka basin. (1) The amplitude of horizontal components of the ground motion at the site-specific period is amplified at each sedimentary station. The predominant period is around 7s in the bayside area where the largest pSv were observed. (2) The velocity Fourier spectra have their peak values around 7s at the bedrock sites surrounding the Osaka basin. (3) Two remarkable wave packets separated by 30s propagating from stations around the Nobi plain to the bedrock sites near the Osaka basin were seen in the pasted-up velocity waveforms from the source regions to the Osaka basin for both events (Sato et al., 2012). Therefore, large long-period ground motions in the Osaka basin are generated by the combination of propagation-path and basin effects. Firstly, we simulate ground motions due to the largest aftershock using three-dimensional FDM (GMS; Aoi and Fujiwara, 1999). The reason we focus on the largest aftershock is that this event has a relatively small rupture area and simple rupture process compared to the mainshock. The source model is based on the model estimated by Kubo et al. (2013). The velocity structure model is a three-dimensional velocity structure based on the Japan Integrated Velocity Structure Model (Koketsu et al., 2012) and the layer of Vs 350m/s in this model is replaced with one of Vs 500m/s. The minimum effective period in this computation is 3s. Then, we compare synthetic waveforms with observed ones. At CHBH14, the nearest station to the source and 60km away from the

  14. Early accumulation of intracellular fibrillar oligomers and late congophilic amyloid angiopathy in mice expressing the Osaka intra-Aβ APP mutation.

    PubMed

    Kulic, L; McAfoose, J; Welt, T; Tackenberg, C; Späni, C; Wirth, F; Finder, V; Konietzko, U; Giese, M; Eckert, A; Noriaki, K; Shimizu, T; Murakami, K; Irie, K; Rasool, S; Glabe, C; Hock, C; Nitsch, R M

    2012-11-13

    Pathogenic amyloid-β peptide precursor (APP) mutations clustered around position 693 of APP-position 22 of the Aβ sequence--are commonly associated with congophilic amyloid angiopathy (CAA) and intracerebral hemorrhages. In contrast, the Osaka (E693Δ) intra-Aβ APP mutation shows a recessive pattern of inheritance that leads to AD-like dementia despite low brain amyloid on in vivo positron emission tomography imaging. Here, we investigated the effects of the Osaka APP mutation on Aβ accumulation and deposition in vivo using a newly generated APP transgenic mouse model (E22ΔAβ) expressing the Osaka mutation together with the Swedish (K670N/M671L) double mutation. E22ΔAβ mice exhibited reduced α-processing of APP and early accumulation of intraneuronal fibrillar Aβ oligomers associated with cognitive deficits. In line with our in vitro findings that recombinant E22Δ-mutated Aβ peptides form amyloid fibrils, aged E22ΔAβ mice showed extracellular CAA deposits in leptomeningeal cerebellar and cortical vessels. In vitro results from thioflavin T aggregation assays with recombinant Aβ peptides revealed a yet unknown antiamyloidogenic property of the E693Δ mutation in the heterozygous state and an inhibitory effect of E22Δ Aβ42 on E22Δ Aβ40 fibrillogenesis. Moreover, E22Δ Aβ42 showed a unique aggregation kinetics lacking exponential fibril growth and poor seeding effects on wild-type Aβ aggregation. These results provide a possible explanation for the recessive trait of inheritance of the Osaka APP mutation and the apparent lack of amyloid deposition in E693Δ mutation carriers.

  15. The prevalence of pandemic (H1N1) 2009 in a suburb of Osaka city--based on reports on the temporary closing of classes.

    PubMed

    Ooe, Yosuke

    2010-07-01

    An outbreak of pandemic (H1N1) 2009 occurred in May 2009 in Osaka and Kobe, Japan. We studied the prevalence of this strain of influenza in Yao City. According to the study, the frequency of temporary class closure did not vary significantly among the first to sixth grades of elementary schools; however, there was a markedly lower frequency of temporary closures among junior high school third-year classes.

  16. The rise and fall of rabies in Japan: A quantitative history of rabies epidemics in Osaka Prefecture, 1914-1933.

    PubMed

    Kurosawa, Aiko; Tojinbara, Kageaki; Kadowaki, Hazumu; Hampson, Katie; Yamada, Akio; Makita, Kohei

    2017-03-01

    Japan has been free from rabies since the 1950s. However, during the early 1900s several large-scale epidemics spread throughout the country. Here we investigate the dynamics of these epidemics between 1914 and 1933 in Osaka Prefecture, using archival data including newspapers. The association between dog rabies cases and human population density was investigated using Mixed-effects models and epidemiological parameters such as the basic reproduction number (R0), the incubation and infectious period and the serial interval were estimated. A total of 4,632 animal rabies cases were reported, mainly in dogs (99.0%, 4,584 cases) during two epidemics from 1914 to 1921, and 1922 to 1933 respectively. The second epidemic was larger (3,705 cases) than the first (879 cases), but had a lower R0 (1.50 versus 2.42). The first epidemic was controlled through capture of stray dogs and tethering of pet dogs. Dog mass vaccination began in 1923, with campaigns to capture stray dogs. Rabies in Osaka Prefecture was finally eliminated in 1933. A total of 3,805 rabid dog-bite injuries, and 75 human deaths were reported. The relatively low incidence of human rabies, high ratio of post-exposure vaccines (PEP) and bite injuries by rabid dogs (minimum 6.2 to maximum 73.6, between 1924 and 1928), and a decline in the proportion of bite victims that developed hydrophobia over time (slope = -0.29, se = 3, p < 0.001), indicated that increased awareness and use of PEP might have prevented disease. Although significantly more dog rabies cases were detected at higher human population densities (slope = 0.66, se = 0.03, p < 0.01), there were fewer dog rabies cases detected per capita (slope = -0.34, se = 0.03, p < 0.01). We suggest that the combination of mass vaccination and restriction of dog movement enabled by strong legislation was key to eliminate rabies. Moreover, the prominent role of the media in both reporting rabies cases and efforts to control the disease likely contributed to

  17. Specific congener profiles of polychlorinated dibenzo-p-dioxins and dibenzofurans in blue mussel in Osaka Bay in Japan: Aqueous solubilities of PCDDs and PCDFs

    SciTech Connect

    Miyata, Hideaki; Takayama, Koji; Mimura, Mayumi; Kashimoto, Takashi ); Fukushima, Shigehiko )

    1989-09-01

    The authors have monitored polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs) in the coastal waters of Japan by using blue mussel (Mytilus edulis) as a biological indicator. The levels of both chemicals were surmised to closely relate to the number of municipal incinerators and the population densities in the cities adjoining the sampling location. The main contamination source in Osaka Bay, which is heavy polluted with PCDDs and PCDFs, was determined to be the fly ash from municipal waste incinerators based upon analytical results of blue mussel from Osaka Bay sediments, sediments from Osaka Bay, and sediments from a river, which is located near a typical urban municipal waste incinerator. However, there was a remarkable difference in congener profiles of PCDDs and PCDFs between the blue mussel and the fly ash, that is, the mussel mainly contained tetraCDDs and tetraCDFs with congener ratios of 56 {plus minus} 9.7% and 62 {plus minus} 6.0%, respectively, whereas the fly ash contained the higher chlorinated PCDDs and PCDFs as major congeners. In this study, the specific congener profiles of PCDDs and PCDFs in blue mussel were investigated from the point of view of their water solubilities.

  18. Impact of eutrophication on shallow marine benthic foraminifers over the last 150 years in Osaka Bay, Japan

    USGS Publications Warehouse

    Tsujimoto, Akira; Nomura, Ritsuo; Yasuhara, Moriaki; Yamazaki, Hideo; Yoshikawa, Shusaku

    2006-01-01

    High-resolution foraminiferal analysis was conducted on a short sediment core from the inner part of Osaka Bay, Japan. Changes in foraminiferal assemblages were associated with eutrophication, bottom water hypoxia, and changes in red tide-causing algae. Before the 1920s, the calcareous species Ammonia beccarii, and the agglutinated species Eggerella advena and Trochammina hadai were rare, but calcareous foraminifers in general were abundant. Between the 1920s and 1940s, calcareous foraminifers decreased abruptly in abundance, while A. beccarii, E. advena and T. hadai increased in abundance. This faunal change corresponded in time to an increase in nutrients flowing in through the Yodo River, and bottom water hypoxia related to eutrophication. In the 1960s and 1970s, A. beccarii, E. advena and T. hadai further increased in abundance to become dominant, and many calcareous foraminifers nearly disappeared, corresponding to increasing bottom water hypoxia related to the rapid increase in discharged nutrients during the high economic growth period from 1953 to 1971. After the 1990s, A. beccarii decreased rapidly in abundance and E. advena and Uvigerinella glabra increased in abundance. The main components of red tide-causing algae changed from dinoflagellates to diatoms in the 1980s through 1990s, thus there was a change in the food supply to the benthos, which may have caused the increase in abundance of E. advena and U. glabra.

  19. A foodborne outbreak of gastrointestinal illness caused by enterotoxigenic Escherichia coli serotype O169:H41 in Osaka, Japan.

    PubMed

    Harada, Tetsuya; Itoh, Kaoru; Yamaguchi, Yuko; Hirai, Yuji; Kanki, Masashi; Kawatsu, Kentaro; Seto, Kazuko; Taguchi, Masumi; Kumeda, Yuko

    2013-01-01

    We describe our laboratory investigation of a massive foodborne outbreak of gastrointestinal illness caused by enterotoxigenic Escherichia coli (ETEC) serotype O169:H41 that occurred during a 2-day traditional festival held in September 2012 in Osaka Prefecture, Japan. Of 126 customers who patronized a particular Japanese restaurant during the event, 102 developed symptoms of gastrointestinal disease. We isolated strains of ETEC serotype O169:H41 from 1 food sample and from fecal samples collected from 19 of 34 patients and 2 of 4 food handlers. Pulsed-field gel electrophoresis analysis of these isolates suggested that the foodborne pathogen that caused the diarrheal outbreak was a specific clone of ETEC serotype O169:H41. Based on these findings and our interviews with the restaurant owner and employees, we concluded that a likely cause of the outbreak was an overwhelmed capacity of the restaurant kitchen in terms of preservation of sanitary procedures during the festival and the inability of the restaurant staff to handle the relatively large quantity of food to ensure a lack of contamination with ETEC. Thus, we reconfirm that ETEC strains of serotype O169:H41 remain important causes of domestic foodborne outbreaks in developed countries, including Japan.

  20. Evaluation of river pollution of neonicotinoids in Osaka City (Japan) by LC/MS with dopant-assisted photoionisation.

    PubMed

    Yamamoto, Atsushi; Terao, Tomoko; Hisatomi, Hirotaka; Kawasaki, Hideya; Arakawa, Ryuichi

    2012-08-01

    An atmospheric pressure photoionisation (APPI) source for liquid chromatography/mass spectrometry (LC/MS) was applied to determine neonicotinoid pesticides in the aquatic environment. Dopant-assisted APPI was very effective in the ionisation of neonicotinoids. Neonicotinoids generated protonated molecules in APPI with high sensitivity, while adduct ions, such as sodiated molecules, were predominantly generated in conventional electrospray ionisation. The ionisation of neonicotinoids was confirmed by ultra-high-resolution MS. An analytical method coupled with solid phase extraction was developed for acetamiprid, clothianidin, dinotefuran, imidacloprid, nitenpyram, and thiamethoxam. Method detection limits were 0.47 to 2.1 ng L(-1) for six neonicotinoids. Dinotefuran was the most frequent and highest among the neonicotinoids examined in the aquatic environment in Osaka, Japan. The maximum concentration of dinotefuran was 220 ng L(-1). Given the toxicity of neonicotinoids for aquatic creatures, the concentrations observed here were substantially low. The change in concentrations was temporally coincident with the period of the neonicotinoid application. Although rapid photodegradation and some degradation products have been elucidated, the degradation products in the aquatic environment were not identified in the present study.

  1. Impact of Coxsackievirus A6 emergence on hand, foot, and mouth disease epidemic in Osaka City, Japan.

    PubMed

    Kanbayashi, Daiki; Kaida, Atsushi; Yamamoto, Seiji P; Hirai, Yuki; Kubo, Hideyuki; Fujimori, Ryoko; Hakui, Noritaka; Hirokawa, Hidetetsu; Iritani, Nobuhiro

    2017-08-03

    Hand, foot, and mouth disease (HFMD) is an acute febrile illness characterized by fever; sore throat; and vesicular eruptions on the hands, feet, and oral mucosa. Until 2010, HFMD was predominantly associated with enterovirus (EV) A71 and coxsackievirus (CV) A16 in Japan. In 2011, CV-A6 emerged as a primary causative agent, causing the largest HFMD epidemic in Japan since 1981. Since then, CV-A6 has caused large HFMD epidemics every 2 years. The phylogenetic analysis of complete Viral Protein 1 (VP1) sequences revealed that most CV-A6 strains detected from 2011 to 2015 in Osaka City were classified into a different clade compared with CV-A6 strains detected from 1999 until 2009. The majority of CV-A6 strains detected in 2011 and most CV-A6 strains detected from 2013 to 2015 were mainly divided into two distinct genetic groups. Each epidemic strain carried unique amino acid substitutions in the presumed DE, EF, and GH loops of the VP1 protein that is exposed on the surface of the virion. There is a possibility that the appearance of substitutions on the surface of the virion and an accumulation of a susceptible population are significant factors in recent HFMD epidemics. © 2017 Wiley Periodicals, Inc.

  2. Polluted and turbid water masses in Osaka Bay and its vicinity revealed with ERTS-A imageries

    NASA Technical Reports Server (NTRS)

    Watanabe, K.

    1973-01-01

    ERTS-1 took very valuable MSS imageries of Osaka Bay and its vicinity on October 24, 1972. In the MSS-4 and MSS-5 imageries a complex grey pattern of water masses can be seen. Though some of grey colored patterns seen in black and white prints of the MSS-4 and MSS-5 imageries are easily identified from their shapes as cloud covers or polluted water masses characterized by their color tone in longer wavelengths in the visible region, any correct distribution pattern of polluted or turbid water masses can be hardly detected separately from thin cloud covers in a quick look analysis. In the present investigation, a simple photographic technique was applied using the fact that reflected sun light from cloud including smog and inclined water surfaces of wave have a certain component in the near infrared region, that MSS-7, whereas the light scattered from fine materials suspended in the sea water has nearly no component sensible in MSS-4 and MSS-5 channels.

  3. Vertical differences in the composition of PM 10 and PM 2.5 in the urban atmosphere of Osaka, Japan

    NASA Astrophysics Data System (ADS)

    Sasaki, Kansuke; Sakamoto, Kazuhiko

    Vertical differences in PM 10 and PM 2.5 suspended particles were investigated using a building in Osaka, Japan. Samples were collected on the roof of the building (200 m above ground level) and on the ground during 5-9 August and 2-6 December 2002. In addition to determination of sample mass, concentrations have been analyzed for major chemical components including elemental carbon (EC) and organic carbon (OC). Particle mass concentrations of the samples collected at 200 m were lower than those collected on the ground. "Others" species, defined as the difference between the total particle mass and the sum of the masses of the measured species, dominantly accounted for the vertical difference in mass concentrations in summer, whereas EC and OC were the major contributors in winter. Vertical profiles of relative humidity observed simultaneously indicated that relative humidity on the ground was higher than that at 200 m during the summer sampling period. Hence, it is likely that the higher concentrations of "others" species in the samples collected on the ground were probably caused by water having been absorbed by deliquescent components of the particles. Vertical temperature profiles during the winter sampling period suggested that stable meteorological conditions in winter resulted in the accumulation of primary particles, mainly emitted from vehicle exhaust, leading to the high concentrations of EC and OC on the ground.

  4. Dietary intake estimations of polybrominated diphenyl ethers (PBDEs) based on a total diet study in Osaka, Japan.

    PubMed

    Akutsu, K; Takatori, S; Nakazawa, H; Hayakawa, K; Izumi, S; Makino, T

    2008-01-01

    This study presents the results of a total diet study performed for estimating the dietary intake of polybrominated diphenyl ethers (PBDEs) in Osaka, Japan. The concentrations of 36 PBDEs were measured in samples from 14 food groups (Groups I-XIV). PBDEs were detected only in Groups IV (oils and fats), V (legumes and their products), X (fish, shellfish, and their products), and XI (meat and eggs) at concentrations of 1.8, 0.03, 0.48, and 0.01 ng g⁻¹, respectively. For an average person, the lower bound dietary intakes of penta- and deca-formulations were estimated to be 46 and 21 ng day⁻¹, respectively. A high proportion of the decabrominated congener (DeBDE-209) was observed in Group IV. To confirm the presence of DeBDE-209 in vegetable oils, an additional analysis was performed using 18 vegetable oil samples. Of these, seven contained ng g⁻¹ levels of DeBDE-209.

  5. [Kaiseijutsu and obstetrics in Osaka during the Yedo era: focusing mainly on the development of surgical operations in obstetrics].

    PubMed

    Uchino, Hanna

    2009-03-01

    In the Yedo era, the Kamigata area was the place of dispatch of new cultures and was the seat of the economy. However, because natural disasters happened frequently, the economic differential between the central area and the provinces grew wider. The families who suffered poverty sold their daughters to the licensed quarters. Moreover, among the general public, there were a lot of foundlings and women who had abortions. Indeed, we can find these phenomena throughout the Yedo era. Early in the era, such cases were regarded as very common; for example, in IHARA Saikaku works, which describes scenes in Osaka early in the Yedo era, there are a lot of descriptions of foundlings and women who had abortions as common social phenomena. However, in the middle of the era, these phenomena came to be considered sins, as they were in Saikaku's works. This transition period of conceptions about foundlings or abortions coincided with changes in technology in obstetrics. Early in the era when dystocia occurred, both mothers and babies could only be expected to die, and in the middle, after the invention of Kaiseijutsu, which was designed by KAGAWA Gen'etsu, obstetricians could help a lot of women in childbirth. However, when abortions came to be regarded as a sin, people accepted Kaiseijutsu because of the concept of life and because it could help women in childbed and babies as medicine, before everything else.

  6. Characteristics and outcomes of emergency patients with self-inflicted injuries: a report from ambulance records in Osaka City, Japan.

    PubMed

    Matsuyama, Tasuku; Kitamura, Tetsuhisa; Kiyohara, Kosuke; Hayashida, Sumito; Kawamura, Takashi; Iwami, Taku; Ohta, Bon

    2016-05-11

    Few studies have evaluated the actual situations of emergency patients with self-inflicted injuries treated by emergency-medical-service (EMS) personnel. This study retrospectively reviewed population-based ambulance records in Osaka City, Japan, between January 2010 and December 2012, and enrolled emergency patients who suffered from self-inflicted injuries such as poisoning by drugs or gas, cutting/piercing skin, jumping from heights, hanging, and drowning. The endpoint was the annual incidence per 100,000 populations in Osaka City of emergency patients who presented with self-inflicted injuries by age and sex. Their outcomes including deaths at the scene and hospital arrival were also evaluated. During the study period, a total of 8,671 patients with 9,424 incidents of self-inflicted injuries were documented. The annual incidence of self-inflicted injuries was higher among women than men in the whole population and in the age group < =49 years (136.9 versus 82.6, and 214.8 versus 93.3, both Ps < 0.001), but it was inversely lower among women in the age group > =50 years (49.0 versus 68.9, P < 0.001). The total number of self-inflicted deaths was 1,564 (16.6 %), and the overall proportion of self-inflicted deaths was greater among men than women (32.2 % [1075/3340] vs. 7.5 % [451/6027], P < 0.001). The proportion of self-inflicted hanging was 76.7 % [1142/1489], followed by poisoning by carbon monoxide at 57.1 % [56/98] and jumping to death at 47.6 % [254/534]. Using large-scale EMS records, we investigated characteristics and outcomes of emergency patients with self-inflicted injuries treated by EMS personnel. Our findings suggested the gender paradox that the proportion of self-inflicted deaths was higher among men than women, while the proportion of non-fatal self-inflicted injuries was higher among women than among men, particularly in the group aged <=49 years. Our findings showing the importance of the prevention for self

  7. Spinal fractures resulting from the 1995 Great Hanshin Earthquake of the Kobe-Osaka area of Japan.

    PubMed

    Maruo, S; Matumoto, M

    1996-07-01

    One of the worst earthquakes hit the Hanshin area between Kobe and Osaka, in the early morning at 5:46 AM on January 17th 1995. The destructive force with MG 7.2 severely damaged buildings, houses, roads and railways, leaving 6500 dead, and 34,900 injured. Hyogo College of Medicine located in this area was also severely damaged, thus there was a major challenge to provide post-quake medical support. A post-quake investigation in this area was done by 50 affiliated hospitals. More than 15,000 victim-patients were treated at these hospitals during the first 3 days after the quake. Major injuries were spinal fractures, and other trunk fractures, including rib or pelvis fractures, but fractures of long bones were uncommon, because the quake hit this area in the early morning when most people were asleep. In this study, the mechanisms of these major injuries were analysed by direct interview soon after the quake, with 230 victim-patients who had 140 spinal fractures, and 100 with rib or pelvis fractures. Most of those who had a spinal fracture had either sat up or stood up on their 'Futon' mattresses without bed frames and were struck on their backs by falling furniture or ceilings. On the other hand, patients who had fractures of the ribs or the pelvis had been lying in the supine or lateral position and were hit on their chest or pelvis. This characteristic lifestyle pattern of the Japanese people to lie down on the floor directly beside furniture, resulted in these injuries. From these results, we will emphasize the following precautions:- If an earthquake occurs during sleeping hours at home, do not stand up or sit up. The best position is to crouch on the 'Futon' mattress.

  8. Factors associated with prehospital death among traffic accident patients in Osaka City, Japan: A population-based study.

    PubMed

    Katayama, Yusuke; Kitamura, Tetsuhisa; Kiyohara, Kosuke; Iwami, Taku; Kawamura, Takashi; Hayashida, Sumito; Ogura, Hiroshi; Shimazu, Takeshi

    2017-06-28

    Although it is important to assess the factors associated with traffic accident fatalities to decrease them as a matter of public health, such factors have not been fully identified. Using a large-scale data set of ambulance records in Osaka City, Japan, we retrospectively analyzed all traffic accident patients transported to hospitals by emergency medical service personnel from 2013 to 2014. In this study, prehospital death was defined as that occurring at the scene or in the emergency department immediately after hospital arrival. We assessed prehospital factors associated with prehospital death due to traffic accidents by logistic regression models. This study enrolled 28,903 emergency patients involved in traffic accidents, of whom 68 died prehospital. In a multivariate model, elderly patients aged ≥75 years (adjusted odds ratio [AOR] = 4.34; 95% confidence interval [CI], 2.29-8.23), nighttime (AOR = 2.75; 95% CI, 1.65-4.70), and type of injured person compared to bicyclists such as pedestrians (AOR = 9.58; 95% CI, 5.07-17.99), motorcyclists (AOR = 2.75; 95% CI, 1.21-6.24), and car occupants (AOR = 2.98; 95% CI, 1.39-6.40) were significantly associated with prehospital death due to traffic accidents. In addition, the AOR for automobile versus nonautomobile as the collision opponent was 4.76 (95% CI, 2.30-9.88). In this population, the factors associated with prehospital death due to traffic accidents were elderly people, nighttime, and pedestrian as the type of patient. The proportion of prehospital deaths due to traffic accidents was also high when the collision component was an automobile.

  9. Cross-sectional and longitudinal investigation of human herpesvirus 8 seroprevalence in HIV-1-infected individuals in Osaka, Japan.

    PubMed

    Watanabe, Dai; Yamamoto, Yudai; Suzuki, Sachiko; Ashida, Misa; Matsumoto, Erina; Yukawa, Satomi; Hirota, Kazuyuki; Ikuma, Motoko; Ueji, Takashi; Kasai, Daisuke; Nishida, Yasuharu; Uehira, Tomoko; Shirasaka, Takuma

    2017-04-01

    High human herpesvirus 8 (HHV-8) seroprevalence has been reported in men who have sex with men (MSM) and are infected with HIV-1. However, it is unclear when they become infected with HHV-8. Thus, we conducted cross-sectional and longitudinal investigations of HHV-8 seroprevalence in HIV-1-infected individuals in Osaka, Japan. Plasma was collected from 121 individuals infected with HIV-1 and the anti-HHV-8 antibody titer was measured using an enzyme-linked immunosorbent assay with whole virus lysate. Subjects were classified into those with and without a past medical history of HHV-8-associated disease; the latter group was then classified into 3 subgroups based on the assumed route of HIV-1 infection: blood products, homosexual contact, and other routes. HHV-8 seroprevalence was compared among the groups and measured again approximately 3 years after the baseline measurement. The relationship between HHV-8 seropositivity and possible associated factors was also investigated. All 15 subjects with HHV-8-associated disease were seropositive, and all 11 subjects in the blood product group were seronegative. In the MSM group, 25 (30%) of 79 subjects were HHV-8 seropositive and, in the non-MSM group, 1 (6%) of 16 subjects was (p < 0.0001). In the longitudinal investigation, seroconversion was observed in 10 (19%) of 52 subjects in the MSM group who were seronegative at baseline. A correlation was observed between seroconversion and symptomatic syphilis (p = 0.0432). HHV-8 seropositivity and seroconversion rates were high in HIV-1-infected MSM, suggesting that, currently, HHV-8 is an epidemic pathogen in this population. Copyright © 2016 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

  10. Hospital characteristics and favourable neurological outcome among patients with out-of-hospital cardiac arrest in Osaka, Japan.

    PubMed

    Matsuyama, Tasuku; Kiyohara, Kosuke; Kitamura, Tetsuhisa; Nishiyama, Chika; Nishiuchi, Tatsuya; Hayashi, Yasuyuki; Kawamura, Takashi; Ohta, Bon; Iwami, Taku

    2017-01-01

    To assess the association between favourable neurological outcome and hospital characteristics such as hospital volume and number of critical care centres (CCMCs) after out-of-hospital cardiac arrest (OHCA). This retrospective, population-based observational study conducted in Osaka Prefecture, Japan included adult patients with OHCA, aged ≥18 years who were transported to acute care hospitals between January 2005 and December 2012. We divided acute care hospitals into CCMCs or non-CCMCs, the latter of which were divided into the following three groups according to the annual average number of transported OHCA cases: low-volume (≤10 cases), middle-volume (11-39 cases), and high-volume (≥40 cases) groups. Random effects logistic regression models, with hospital treated as a random effect, were used to assess factors potentially associated with a favourable neurological outcome. A total of 44,474 patients were eligible. The proportions of favourable neurological outcome from OHCA were 0.9% (31/3559) in the low-volume group, 1.2% (106/9171) in the middle-volume group, 1.6% (222/14,007) in the high-volume group, and 4.3% (766/17,737) in the CCMC group (P<0.001). In the multivariable analysis, transport to CCMCs was significantly associated with favourable neurological outcome, compared with transport to non-CCMCs (adjusted odds ratio 1.63; 95% confidence interval, 1.60-1.66). Among the non-CCMC group, there was no significant relationship between hospital volume and favourable neurological outcome. In this population, transport of OHCA patients to CCMCs led to significantly higher one-month survival rates with favourable neurological outcome from OHCA, whereas no significant association was noted among the hospitals with different volumes. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  11. Effects of preventive health services on survival of the elderly living in a community in Osaka, Japan.

    PubMed Central

    Nakanishi, N; Tatara, K; Tatatorige, T; Murakami, S; Shinsho, F

    1997-01-01

    STUDY OBJECTIVE: To examine the relationships between the use of preventive health services--such as health checks, basic health examination/cancer screening, and daily preventive health practices--and survival of elderly people living in the community. DESIGN AND SETTING: A cohort of elderly people aged 65 years and over living in Settsu City, Osaka was followed for 38 months. Data on the history of health management, disability scores, and psychosocial conditions were collected in October 1992 by interview during home visits. SUBJECTS: Of the 1491 people randomly selected from the computerised sex-age register at enrollment, 1473 were contacted and responses were obtained from 1405 (95.4%). They constituted the study cohort. Follow up was completed for 1325 (94.3%) (154 decreased and 1171 alive). MEASUREMENTS AND MAIN RESULTS: From the analysis using the Kaplan-Meier method and the log-rank test, female sex, younger age group (65-74 years), use of health checks, use of basic health examination and/or cancer screening, use of daily preventive health practices, less disability, taking part in social activity, and finding life worth living were univariately statistically significantly related to survival. The estimated survival rates were highest in those with regular health checks or daily preventive health practices before 59 years of age or both basic health examination and cancer screening. From the Cox proportional hazards model, use of health checks and use of daily preventive health practices remained as statistically significant factors associated with survival, controlling for other factors such as sex, age group, medical treatment, disability scores, and psycho-social conditions, and these hazard ratios (not used v starting at 59 years) were 0.41 (95% CI, 0.25, 0.66) and 0.52 (95% CI, 0.30, 0.88), respectively. CONCLUSIONS: Health management efforts such as health checks and daily preventive health practices may increase survival in the elderly. PMID

  12. [Equipment at the special nursing homes for the elderly: a workplace survey of new nursing homes in Osaka Prefecture].

    PubMed

    Tomioka, Kimiko; Kumagai, Shinji; Kosaka, Hiroshi; Yoshida, Jin; Tabuchi, Takeo; Kosaka, Junko; Arai, Yasutomo

    2006-03-01

    The number of those who need nursing care and the workers who provide it have been increasing year after year. In April 2000, the public nursing care insurance system was enacted by the Japanese government. After its enaction, care equipment came under scrutiny, but the situation regarding the installation of equipment is not fully understood. In order to understand the present state of care equipment in nursing facilities for the elderly, we conducted a workplace and interview survey. The surveyed facilities were 10 special nursing homes for the elderly in Osaka Prefecture which were established after April 2002. The average number of elderly residents was 79.0, the average value of degree of care was 3.52, and the average number of caregivers was 28.3 per facility. We found all facilities had installed some kinds of bathing equipment: stretcher type, 9 facilities; bath-chair type, 8 facilities. In the facilities with bath-chairs, 6 facilities had special bathtubs, and 6 facilities had general bathtubs. However, all facilities had the working principle that transfer should be done manually, and the equipment for transfer such as a lifts, a transfer and roller board were not be installed. In changing diapers, bed height adjustment was not possible. And the Japanese standard type of wheelchair has a non-detachable armrest, creating a structural barrier when transferring elderly people from a wheelchair to a toilet seat. At all facilities the basis of care was that caregivers should do it manually. In particular, all facilities had only a weak recognition of the risks of transfer. This investigation shows that facilities for the elderly should rethink elderly care based on a reduction of care load and most importantly protection of caregivers' health.

  13. Trends in Lung Cancer Incidence Rates by Histological Type in 1975–2008: A Population-Based Study in Osaka, Japan

    PubMed Central

    Kinoshita, Fukuaki Lee; Ito, Yuri; Nakayama, Tomio

    2016-01-01

    Background Monitoring trends in lung cancer incidence and mortality is important for the evaluation of cancer control activities. We investigated recent trends in age-standardized incidence rates by histological type of lung cancer in Osaka, Japan. Methods Cancer incidence data for 1975–2008 were obtained from the Osaka Cancer Registry. Lung cancer mortality data with population data in Osaka during 1975–2012 were obtained from vital statistics. We examined trends in age-standardized incidence and mortality rates for all histological types and age-standardized incidence rates by histological type and age group using a joinpoint regression model. Results The age-standardized incidence rate of lung cancer levelled off or slightly increased from 1975–2008, with an annual percentage change of 0.3% (95% confidence interval [CI], 0.1%–0.4%) for males and 1.1% (95% CI, 0.9%–1.3%) for females, and the mortality rate decreased by 0.9% (95% CI, 1.2%–0.7%) for males and 0.5% (95% CI, 0.8%–0.3%) for females. The incidence rates of squamous cell carcinoma (SQC) and small cell carcinoma (SMC) significantly decreased for both genders, whereas that of adenocarcinoma (ADC) significantly increased among almost all age groups in both genders. Conclusions The incidence rates of SQC and SMC decreased with the decline in smoking prevalence, which probably explains the change in trends in the incidence rates of lung cancer from the mid-1980s. However, the reason for the increase in ADC remains unclear. Therefore, trends in incidence rates of lung cancer should be carefully monitored, especially for ADC, and the associations between ADC and its possible risk factors should be studied. PMID:27150013

  14. The E693Δ (Osaka) mutation in amyloid precursor protein potentiates cholesterol-mediated intracellular amyloid β toxicity via its impaired cholesterol efflux.

    PubMed

    Nomura, Sachiko; Umeda, Tomohiro; Tomiyama, Takami; Mori, Hiroshi

    2013-12-01

    It has been shown that amyloid β (Aβ) secretion regulates cholesterol efflux from cells and that the E693Δ (Osaka) mutation in amyloid precursor protein (APP) promotes intracellular accumulation of Aβ and thus reduces its secretion. These findings led us to speculate that APP with the Osaka mutation (APPOSK ) might have a defect in cholesterol efflux and thus cause cellular malfunction. We therefore examined the effects of this mutation on intracellular cholesterol transport and efflux in cultured cells. Upon cholesterol loading, APPOSK -expressing cells exhibited higher levels of cellular cholesterol than wild-type APP-expressing cells, suggesting impaired cholesterol efflux. It is known that, after its internalization, cholesterol is transported from the endosomes to the endoplasmic reticulum (ER) and Golgi apparatus and then to the plasma membrane. In APPOSK -expressing cells, cholesterol accumulated with Aβ in the ER and Golgi apparatus and alone in endosomes/lysosomes. These results imply that the mutation-induced disturbance of Aβ trafficking from the ER to the plasma membrane affects cholesterol transport to cause cholesterol accumulation in the ER and Golgi apparatus and, consequently, in endosomes. Furthermore, we detected an enhanced mitochondrial accumulation of Aβ and cholesterol in APPOSK -expressing cells, and this was accompanied by an increase in the generation of reactive oxygen species (ROS). The present findings suggest that Aβ trafficking is important for intracellular cholesterol transport and efflux and that the Osaka mutation potentiates cholesterol-dependent exacerbation of intracellular Aβ toxicity, i.e. Aβ-induced ROS generation, by disturbing Aβ-mediated cholesterol efflux from the cell. Copyright © 2013 Wiley Periodicals, Inc.

  15. Trends in Lung Cancer Incidence Rates by Histological Type in 1975-2008: A Population-Based Study in Osaka, Japan.

    PubMed

    Kinoshita, Fukuaki Lee; Ito, Yuri; Nakayama, Tomio

    2016-11-05

    Monitoring trends in lung cancer incidence and mortality is important for the evaluation of cancer control activities. We investigated recent trends in age-standardized incidence rates by histological type of lung cancer in Osaka, Japan. Cancer incidence data for 1975-2008 were obtained from the Osaka Cancer Registry. Lung cancer mortality data with population data in Osaka during 1975-2012 were obtained from vital statistics. We examined trends in age-standardized incidence and mortality rates for all histological types and age-standardized incidence rates by histological type and age group using a joinpoint regression model. The age-standardized incidence rate of lung cancer levelled off or slightly increased from 1975-2008, with an annual percentage change of 0.3% (95% confidence interval [CI], 0.1%-0.4%) for males and 1.1% (95% CI, 0.9%-1.3%) for females, and the mortality rate decreased by 0.9% (95% CI, 1.2%-0.7%) for males and 0.5% (95% CI, 0.8%-0.3%) for females. The incidence rates of squamous cell carcinoma (SQC) and small cell carcinoma (SMC) significantly decreased for both genders, whereas that of adenocarcinoma (ADC) significantly increased among almost all age groups in both genders. The incidence rates of SQC and SMC decreased with the decline in smoking prevalence, which probably explains the change in trends in the incidence rates of lung cancer from the mid-1980s. However, the reason for the increase in ADC remains unclear. Therefore, trends in incidence rates of lung cancer should be carefully monitored, especially for ADC, and the associations between ADC and its possible risk factors should be studied.

  16. Influence of the 2009 financial crisis on detection of advanced pulmonary tuberculosis in Osaka city, Japan: a cross-sectional study.

    PubMed

    Danno, Katsura; Komukai, Jun; Yoshida, Hideki; Matsumoto, Kenji; Koda, Shinichi; Terakawa, Kazuhiko; Iso, Hiroyasu

    2013-01-01

    To investigate the association between the economic recession and the detection of advanced cases of pulmonary tuberculosis in Osaka city from 2007 to 2009. A repeated cross-sectional study. Osaka city has been the highest tuberculosis burden area in Japan. After the previous global financial crisis, the unemployment rate in Osaka prefecture has deteriorated from 5.3% in 2008 to 6.6% in 2009. During the study period, 3406 pulmonary tuberculosis cases were enrolled: 2530 males and 876 females; 1546 elderly cases (65 years and above) and 1860 young cases (under 65 years); 417 homeless cases and 2989 non-homeless cases. Patients' information included the sex, age, registry, health insurances, places of detection, sputum smear test results, patients' delay, doctors' delay and the grade of chest x-ray findings. They were statistically analysed between 2007 and 2008, two years before and just before the financial crisis, and between 2008 and 2009, just before and after the financial crisis. The total numbers of pulmonary tuberculosis cases were 1172 in 2007, 1083 in 2008 and 1151 in 2009. In health examinations for non-homeless people, higher number of cases in 2009 were sputum smear positive, had respiratory symptoms and showed advanced disease in chest x-rays than those in 2008, with a longer patients' delay. On the contrary, in health examination for homeless people, fewer cases of advanced pulmonary tuberculosis were found in 2009 than in 2008, with a shorter patients' delay. In clinical examinations, there was no trend towards a difference between non-homeless and homeless people. Although homeless people might be protected by public assistance, tuberculosis prevention and control need to be reinforced for the non-homeless population after the financial crisis.

  17. Influence of the 2009 financial crisis on detection of advanced pulmonary tuberculosis in Osaka city, Japan: a cross-sectional study

    PubMed Central

    Danno, Katsura; Komukai, Jun; Yoshida, Hideki; Matsumoto, Kenji; Koda, Shinichi; Terakawa, Kazuhiko; Iso, Hiroyasu

    2013-01-01

    Objective To investigate the association between the economic recession and the detection of advanced cases of pulmonary tuberculosis in Osaka city from 2007 to 2009. Design A repeated cross-sectional study. Setting Osaka city has been the highest tuberculosis burden area in Japan. After the previous global financial crisis, the unemployment rate in Osaka prefecture has deteriorated from 5.3% in 2008 to 6.6% in 2009. Participants During the study period, 3406 pulmonary tuberculosis cases were enrolled: 2530 males and 876 females; 1546 elderly cases (65 years and above) and 1860 young cases (under 65 years); 417 homeless cases and 2989 non-homeless cases. Outcome measures Patients’ information included the sex, age, registry, health insurances, places of detection, sputum smear test results, patients’ delay, doctors’ delay and the grade of chest x-ray findings. They were statistically analysed between 2007 and 2008, two years before and just before the financial crisis, and between 2008 and 2009, just before and after the financial crisis. Results The total numbers of pulmonary tuberculosis cases were 1172 in 2007, 1083 in 2008 and 1151 in 2009. In health examinations for non-homeless people, higher number of cases in 2009 were sputum smear positive, had respiratory symptoms and showed advanced disease in chest x-rays than those in 2008, with a longer patients’ delay. On the contrary, in health examination for homeless people, fewer cases of advanced pulmonary tuberculosis were found in 2009 than in 2008, with a shorter patients’ delay. In clinical examinations, there was no trend towards a difference between non-homeless and homeless people. Conclusions Although homeless people might be protected by public assistance, tuberculosis prevention and control need to be reinforced for the non-homeless population after the financial crisis. PMID:23558729

  18. Regional distribution of PM2.5 over a megacity Osaka in Japan derived from satellite, AERONET and/or LIDAR measurements

    NASA Astrophysics Data System (ADS)

    Sano, I.; Mukai, S.; Nakata, M.; Holben, B.; Sugimoto, N.

    2012-04-01

    Monitoring of particulate matter near the surface is very important for the Earth environment, especially for human health and atmospheric environment. In Japan, concentration of suspended particulate matter (SPM), which is similar to PM10 but sharply cutting at 10 µm for the particle diameter, has been monitored since 1975 and is still now widely available for a daily monitoring. New PM2.5 rule was defined in 1997 in the United States, however the standard rule for PM2.5 monitoring has net yet made in Japan until 2009. As a result, the number of PM2.5 instruments is very limited in Japan. In practice the PM2.5 samplers are only used for scientific objects. Therefore estimation of PM2.5 over the wide area as possible as in Japan is an urgent issue. Anthropogenic small particles dominate the air especially over the urban areas because of local emissions by diesel vehicles and industries. The distribution of these particles is complicated due to the increasing emissions of sulfuric, nitric, carbonaceous and other aerosols in association with economic growth in East Asia. The goal of this work is to estimate PM2.5 distribution over the second big city Osaka in Japan based on satellite measurements. A brief processing line of PM2.5 estimation is as follows: 1. Acquirement of surface reflectance based on satellite data to retrieve aerosol characteristics. 2. Retrieval of columnar aerosol optical thickness (AOT) over Osaka from the fine resolved satellite image. 3. Vertical profile of aerosol concentration with NIES-LIDAR measurements. 4. Surface level aerosol optical depth (AOD) derived from columnar AOT and LIDAR dataset. 5. Estimation of PM2.5 based on the relationship between AOT, surface AOD, LIDAR and in-situ PM2.5 dataset simultaneously accumulated at AERONET/Osaka site since 2008. Note that, collocated data set of in situ PM2.5, AERONET AOT, and NIES-LIDAR data are available at Kinki University's AERONET site as mentioned in the above item 5. It is of interest

  19. Mutation-induced loss of APP function causes GABAergic depletion in recessive familial Alzheimer's disease: analysis of Osaka mutation-knockin mice.

    PubMed

    Umeda, Tomohiro; Kimura, Tetsuya; Yoshida, Kayo; Takao, Keizo; Fujita, Yuki; Matsuyama, Shogo; Sakai, Ayumi; Yamashita, Minato; Yamashita, Yuki; Ohnishi, Kiyouhisa; Suzuki, Mamiko; Takuma, Hiroshi; Miyakawa, Tsuyoshi; Takashima, Akihiko; Morita, Takashi; Mori, Hiroshi; Tomiyama, Takami

    2017-07-31

    The E693Δ (Osaka) mutation in APP is linked to familial Alzheimer's disease. While this mutation accelerates amyloid β (Aβ) oligomerization, only patient homozygotes suffer from dementia, implying that this mutation is recessive and causes loss-of-function of amyloid precursor protein (APP). To investigate the recessive trait, we generated a new mouse model by knocking-in the Osaka mutation into endogenous mouse APP. The produced homozygous, heterozygous, and non-knockin littermates were compared for memory, neuropathology, and synaptic plasticity. Homozygotes showed memory impairment at 4 months, whereas heterozygotes did not, even at 8 months. Immunohistochemical and biochemical analyses revealed that only homozygotes displayed intraneuronal accumulation of Aβ oligomers at 8 months, followed by abnormal tau phosphorylation, synapse loss, glial activation, and neuron loss. These pathologies were not observed at younger ages, suggesting that a certain mechanism other than Aβ accumulation underlies the memory disturbance at 4 months. For the electrophysiology studies at 4 months, high-frequency stimulation evoked long-term potentiation in all mice in the presence of picrotoxin, but in the absence of picrotoxin, such potentiation was observed only in homozygotes, suggesting their GABAergic deficit. In support of this, the levels of GABA-related proteins and the number of dentate GABAergic interneurons were decreased in 4-month-old homozygotes. Since APP has been shown to play a role in dentate GABAergic synapse formation, the observed GABAergic depletion is likely associated with an impairment of the APP function presumably caused by the Osaka mutation. Oral administration of diazepam to homozygotes from 6 months improved memory at 8 months, and furthermore, prevented Aβ oligomer accumulation, indicating that GABAergic deficiency is a cause of memory impairment and also a driving force of Aβ accumulation. Our findings suggest that the Osaka mutation

  20. Characteristics of the abundance of polychlorinated dibenzo-p-dioxin and dibenzofurans, and dioxin-like polychlorinated biphenyls in sediment samples from selected Asian regions in Can Gio, Southern Vietnam and Osaka, Japan.

    PubMed

    Kishida, Masao; Imamura, Kiyoshi; Takenaka, Norimichi; Maeda, Yasuaki; Viet, Pham Hung; Kondo, Akira; Bandow, Hiroshi

    2010-01-01

    The levels of polychlorinated dibenzo-p-dioxin and dibenzofuran (PCDD/PCDFs), and dioxin-like polychlorinated biphenyls (DL-PCBs) were determined in sediment samples from Can Gio, South Vietnam, and Osaka, Japan. Can Gio is known for the defoliation of its mangrove forests by aerial spraying with Agent Orange during the Vietnam War, whereas Osaka is renowned for a PCDD/PCDF pollution accident at a municipal solid-waste incinerator. For comparison, we also analyzed PCDD/PCDFs and DL-PCBs in sediment samples from Hue and Hanoi, Vietnam. The toxic equivalent quantity (TEQ) values in Can Gio were as high as those in Hue, Hanoi, and suburban areas of Osaka, but much lower than those in urban areas of Osaka. The proportion of the World Health Organization (WHO)-TEQ value contributed by 2,3,7,8-tetrachlorinated dibenzo-p-dioxin (TCDD) in Can Gio was approximately 30%, higher than the values in the other sample areas. These data suggest that residual sedimentary TCDD that originated from aerial spraying of Agent Orange occur in only low concentrations in Can Gio. The main contributors to WHO-TEQ values in Can Gio are natural sources, as in Hue. In contrast, commercial PCBs are the dominant contributors to WHO-TEQ values in Hanoi. In Osaka, agrochemicals used in rice cultivation, the incineration of solid waste, and commercial PCBs equally contributed to WHO-TEQ values at suburban locations. The dumping of incinerator-related materials and/or the inadequate management of commercial PCBs have resulted in significantly elevated WHO-TEQ values of 240-370 ng kg(-1)dw at urban locations in Osaka.

  1. Comparison of particle-phase polycyclic aromatic hydrocarbons and their variability causes in the ambient air in Ho Chi Minh City, Vietnam and in Osaka, Japan, during 2005-2006.

    PubMed

    Hien, To Thi; Nam, Pham Phuong; Yasuhiro, Sadanaga; Takayuki, Kameda; Norimichi, Takenaka; Hiroshi, Bandow

    2007-08-15

    A comparative study of polycyclic aromatic hydrocarbons (PAHs) associated with particulate matter (TSP) in the ambient air in an urban area in Ho Chi Minh City, Vietnam and in Osaka, Japan was carried out from 2005 to 2006. The objective of this study was to investigate the environmental levels, emission sources, seasonal variations and health risk of eleven PAHs in the two cities, especially Ho Chi Minh City where air pollution is becoming a serious concern. The results showed that the concentrations of TSP and total PAHs were significantly higher in Ho Chi Minh City than levels in Osaka. The concentrations of 5- and 6-ring PAHs (BeP, BbF, BkF, BaP, BghiP and InP) were much higher in TSP samples in Ho Chi Minh City than in Osaka, accounting for 82% and 51% of total PAHs, respectively. These PAHs are known to be highly carcinogenic and mutagenic in humans. Vehicular emission is suggested as one of the main pollution sources of PAHs in both cities. Motorcycles and gasoline automobiles are suggested as the main emission sources of PAHs in Ho Chi Minh City, whereas diesel automobiles are the primary source in Osaka. Seasonal variations of PAHs were observed in this study; higher concentrations of PAHs were found in the rainy season (May-December) and lower concentrations corresponded to the dry season (February-April) in Ho Chi Minh City, while higher concentrations of PAHs were observed in the winter (November-January) in Osaka. The number of sunshine hours was an important meteorological factor affecting seasonal variations of PAHs in Ho Chi Minh City, while the temperature was a main factor causing the variations of PAHs in Osaka. The high BaP equivalent concentration of 5- and 6-ring PAHs even in the ambient air is an alarming signal for harmfulness to human health and environmental quality in Ho Chi Minh City.

  2. Incidence and outcomes of emergency self-harm among adolescents: a descriptive epidemiological study in Osaka City, Japan

    PubMed Central

    Matsuyama, Tasuku; Kitamura, Tetsuhisa; Kiyohara, Kosuke; Hayashida, Sumito; Nitta, Masahiko; Kawamura, Takashi; Iwami, Taku; Ohta, Bon

    2016-01-01

    Objectives To evaluate the incidence and outcomes of self-harm from ambulance records. Design A retrospective, observational study. Setting Osaka City, Japan. Participants A total of 365 adolescents aged 10–19 years with emergency self-harm such as poisoning by drugs or gas, cutting skin, jumping from heights, hanging and drowning and treated by emergency medical service personnel from January 2010 through December 2012. Primary outcome measurements Incidence per 100 000 persons and outcome at the scene or hospital arrival by age and gender. Poisson regression models for incidence evaluation were used; reporting relative risks (RRs) and their 95% CIs. Results During the study period, a total of 425 self-harm events were documented in 365 adolescents. The incidence of self-harm increased significantly between the ages of 11 and 19 years, from 6.3 to 81.0 among boys and the ages of 12 and 19 years from 6.3 to 228.3 among girls, respectively (both p<0.001). Although there was no incidence difference between girls and boys in the group aged 11–14 years (RR 1.20; 95% CI 0.59 to 2.47), the incidence was significantly higher among girls than boys in the group aged 15–19 years (RR 4.18; 95% CI 3.20 to 5.45). The overall proportion of death by self-harm was 4.9%. The proportion of hospital admission and death by self-harm was higher among boys than among girls (38.6% vs 25.2%, p=0.016 and 14.8% vs 2.4%, p<0.001). Conclusions The incidence of emergency treatment for self-harm by adolescents increased with age and our findings also demonstrated the gender paradox. It would be necessary to establish active, gender-specific and comprehensive prevention strategies for adolescent self-harm, based on our findings showing the age and gender differences of self-harm among adolescents. PMID:27381208

  3. Measurement of characteristics of an infrared free-electron laser with the L-band at Osaka University

    SciTech Connect

    Okuda, S.; Ishida, S.; Honda, Y.

    1995-12-31

    Free-electron laser (FEL) experiments have been conducted with the 38-MeV L-band electron linac at the Institute of Scientific and Industrial Research, Osaka University. It is a 1.3 GHz RF linac with a thermoionic gun, and equipped with two 12th and one 6th sub-harmonic prebunchers for producing the high-intensity single-bunch beam with a charge up to 67 nC/bunch. For oscillation experiments of FEL, the gun is replaced with that with a smaller cathode area in order to reduce the emittance of the beam. The normalized emittance has been measured to be 200 {pi} mm-mrad. The linac is operated in the long-pulse mode and one of the 12th sub-harmonic bunchers and the 6th sub-harmonic buncher are operated, so that the time duration of the macropulse is 4 {mu}s and the spacing between micropulses is 9.2 ns. The length of the micropulse is 30-40 ps and the charge in each micropulse is 2 nC. The electron beam from the linac is transported to a wiggler which has the period length of 6 cm and the number of periods of 32. The first half of the macropulse is lost in the transport line because the energy of electrons in that part gradually changes and there is a momentum slit in the transport line. An optical resonator is 5.53 m long and the round-trip time of light in it is 37 ns, which is precisely four times as long as the spacing of micropulses. Since the time duration of the macropulse passing through the wiggler is 1.8 {mu}s, the number of amplifications of light in the cavity is 49. The first lasing was achieved in 1994 at wavelengths between 32 and 40 {mu}m and preliminary results were reported at the l6th FEL Conference last year. The laser light was detected with a Ge:Be detector which has the time resolution of 3 {mu}s. Since the time duration of the macropulse of the laser fight is estimated to be less than 2 {mu}s, we could measure only the total energy in a macropulse of the output light.

  4. Incidence and outcomes of emergency self-harm among adolescents: a descriptive epidemiological study in Osaka City, Japan.

    PubMed

    Matsuyama, Tasuku; Kitamura, Tetsuhisa; Kiyohara, Kosuke; Hayashida, Sumito; Nitta, Masahiko; Kawamura, Takashi; Iwami, Taku; Ohta, Bon

    2016-07-05

    To evaluate the incidence and outcomes of self-harm from ambulance records. A retrospective, observational study. Osaka City, Japan. A total of 365 adolescents aged 10-19 years with emergency self-harm such as poisoning by drugs or gas, cutting skin, jumping from heights, hanging and drowning and treated by emergency medical service personnel from January 2010 through December 2012. Incidence per 100 000 persons and outcome at the scene or hospital arrival by age and gender. Poisson regression models for incidence evaluation were used; reporting relative risks (RRs) and their 95% CIs. During the study period, a total of 425 self-harm events were documented in 365 adolescents. The incidence of self-harm increased significantly between the ages of 11 and 19 years, from 6.3 to 81.0 among boys and the ages of 12 and 19 years from 6.3 to 228.3 among girls, respectively (both p<0.001). Although there was no incidence difference between girls and boys in the group aged 11-14 years (RR 1.20; 95% CI 0.59 to 2.47), the incidence was significantly higher among girls than boys in the group aged 15-19 years (RR 4.18; 95% CI 3.20 to 5.45). The overall proportion of death by self-harm was 4.9%. The proportion of hospital admission and death by self-harm was higher among boys than among girls (38.6% vs 25.2%, p=0.016 and 14.8% vs 2.4%, p<0.001). The incidence of emergency treatment for self-harm by adolescents increased with age and our findings also demonstrated the gender paradox. It would be necessary to establish active, gender-specific and comprehensive prevention strategies for adolescent self-harm, based on our findings showing the age and gender differences of self-harm among adolescents. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  5. The F Gene of the Osaka-2 Strain of Measles Virus Derived from a Case of Subacute Sclerosing Panencephalitis Is a Major Determinant of Neurovirulence▿

    PubMed Central

    Ayata, Minoru; Takeuchi, Kaoru; Takeda, Makoto; Ohgimoto, Shinji; Kato, Seiichi; Sharma, Luna Bhatta; Tanaka, Miyuu; Kuwamura, Mitsuru; Ishida, Hiroshi; Ogura, Hisashi

    2010-01-01

    Measles virus (MV) is the causative agent for acute measles and subacute sclerosing panencephalitis (SSPE). Although numerous mutations have been found in the MV genome of SSPE strains, the mutations responsible for the neurovirulence have not been determined. We previously reported that the SSPE Osaka-2 strain but not the wild-type strains of MV induced acute encephalopathy when they were inoculated intracerebrally into 3-week-old hamsters. The recombinant MV system was adapted for the current study to identify the gene(s) responsible for neurovirulence in our hamster model. Recombinant viruses that contained envelope-associated genes from the Osaka-2 strain were generated on the IC323 wild-type MV background. The recombinant virus containing the M gene alone did not induce neurological disease, whereas the H gene partially contributed to neurovirulence. In sharp contrast, the recombinant virus containing the F gene alone induced lethal encephalopathy. This phenotype was related to the ability of the F protein to induce syncytium formation in Vero cells. Further study indicated that a single T461I substitution in the F protein was sufficient to transform the nonneuropathogenic wild-type MV into a lethal virus for hamsters. PMID:20719945

  6. Circadian variation of the onset of acute myocardial infarction in the Osaka area, 1998-1999: characterization of morning and nighttime peaks.

    PubMed

    Kinjo, K; Sato, H; Sato, H; Shiotani, I; Kurotobi, T; Ohnishi, Y; Hishida, E; Nakatani, D; Ito, H; Koretsune, Y; Hirayama, A; Tanouchi, J; Mishima, M; Kuzuya, T; Takeda, H; Hori, M

    2001-07-01

    The onset of acute myocardial infarction (AMI) shows characteristic circadian variations; that is, a definite morning peak related to biologic rhythms and a vague nighttime peak related to socioeconomic factors. The recent economic recession in Japan may change the circadian variation, especially the nighttime peak. This study evaluated the recent circadian variation of AMI in Osaka and specified the patient subgroups showing either a morning or nighttime peak predominantly. Of 1,609 consecutive patients with AMI registered from April 1998 to January 2000, 1,252 whose onset of AMI was definitely identified were studied. The day was divided into six 4-h periods with a morning peak between 08.01 h and 12.00h, and nighttime peak between 20.01 h and 24.00h. When subgroup analysis was performed, female patients aged 65 years or more showed a morning peak alone and male patients aged less than 65 years with an occupation and the habits of cigarette smoking and alcohol intake showed a nighttime peak alone. Thus, in Osaka nighttime socioeconomic factors may currently be more potent triggers of AMI than the morning surges in younger male workers who smoke and drink.

  7. Development on Multi-Turn TOF-SIMS with a Femto-Second Laser for Post-Ionization: First Application of OPTIMA (Osaka PosT-Ionization MAss spectrometer) for Presolar SiCs

    NASA Astrophysics Data System (ADS)

    Terada, Kentaro; Kawai, Yosuke; Toyoda, Michisato; Ishihara, Morio; Aoki, Jun; Yabuta, Hikaru; Miya, Kohei; Suwa, Taichi; Matsuda, Takahiro; Nakamura, Ryosuke

    In the Earth and Planetary science, high-sensitive, high-spacial resolution and high-mass resolution mass spectrometer is indispensable. Here we report on the specification of a new-designed multi-turn TOF-SIMS (OPTIMA: Osaka PosT-Ionization Mass spectrometer) and the first application for presolar SiCs from primitive meteorite.

  8. Amino acid substitutions in the heptad repeat A and C regions of the F protein responsible for neurovirulence of measles virus Osaka-1 strain from a patient with subacute sclerosing panencephalitis.

    PubMed

    Ayata, Minoru; Tanaka, Miyuu; Kameoka, Kazuo; Kuwamura, Mitsuru; Takeuchi, Kaoru; Takeda, Makoto; Kanou, Kazuhiko; Ogura, Hisashi

    2016-01-01

    Measles virus (MV) is the causative agent of subacute sclerosing panencephalitis (SSPE). We previously reported that the F gene of the SSPE Osaka-2 strain is the major determinant of MV neurovirulence. Because the sites and extents of mutations differ among SSPE strains, it is necessary to determine the mutations responsible for the SSPE-specific phenotypes of individual viral strain. In this study, recombinant viruses containing the envelope-associated genes from the SSPE Osaka-1 strain were generated in the IC323 wild-type MV background. Hamsters inoculated with MV containing the H gene of the Osaka-1 strain displayed hyperactivity and seizures, but usually recovered and survived. Hamsters inoculated with MV containing the F gene of the Osaka-1 strain displayed severe neurologic signs and died. Amino acid substitutions in the heptad repeat A and C regions of the F protein, including a methionine-to-valine substitution at amino acid 94, play major roles in neurovirulence. Copyright © 2015 Elsevier Inc. All rights reserved.

  9. Estimated Dietary Intake of Radionuclides and Health Risks for the Citizens of Fukushima City, Tokyo, and Osaka after the 2011 Nuclear Accident

    PubMed Central

    Murakami, Michio; Oki, Taikan

    2014-01-01

    The radionuclides released from the Fukushima Daiichi nuclear power plant in 2011 pose a health risk. In this study, we estimated the 1st-year average doses resulting from the intake of iodine 131 (131I) and cesium 134 and 137 (134Cs and 137Cs) in drinking water and food ingested by citizens of Fukushima City (∼50 km from the nuclear power plant; outside the evacuation zone), Tokyo (∼230 km), and Osaka (∼580 km) after the accident. For citizens in Fukushima City, we considered two scenarios: Case 1, citizens consumed vegetables bought from markets; Case 2, citizens consumed vegetables grown locally (conservative scenario). The estimated effective doses of 134Cs and 137Cs agreed well with those estimated through market basket and food-duplicate surveys. The average thyroid equivalent doses due to ingestion of 131I for adults were 840 µSv (Case 1) and 2700 µSv (Case 2) in Fukushima City, 370 µSv in Tokyo, and 16 µSv in Osaka. The average effective doses due to 134Cs and 137Cs were 19, 120, 6.1, and 1.9 µSv, respectively. The doses estimated in this study were much lower than values reported by the World Health Organization and the United Nations Scientific Committee on the Effects of Atomic Radiation, whose assessments lacked validation and full consideration of regional trade in foods, highlighting the importance of including regional trade. The 95th percentile effective doses were 2–3 times the average values. Lifetime attributable risks (LARs) of thyroid cancers due to ingestion were 2.3–39×10−6 (Case 1) and 10–98×10−6 (Case 2) in Fukushima City, 0.95–14×10−6 in Tokyo, and 0.11–1.3×10−6 in Osaka. The contributions of LARs of thyroid cancers due to ingestion were 7.5%–12% of all exposure (Case 1) and 12%–30% (Case 2) in Fukushima City. PMID:25390339

  10. Estimated dietary intake of radionuclides and health risks for the citizens of Fukushima City, Tokyo, and Osaka after the 2011 nuclear accident.

    PubMed

    Murakami, Michio; Oki, Taikan

    2014-01-01

    The radionuclides released from the Fukushima Daiichi nuclear power plant in 2011 pose a health risk. In this study, we estimated the 1st-year average doses resulting from the intake of iodine 131 (131I) and cesium 134 and 137 (134Cs and 137Cs) in drinking water and food ingested by citizens of Fukushima City (∼50 km from the nuclear power plant; outside the evacuation zone), Tokyo (∼230 km), and Osaka (∼580 km) after the accident. For citizens in Fukushima City, we considered two scenarios: Case 1, citizens consumed vegetables bought from markets; Case 2, citizens consumed vegetables grown locally (conservative scenario). The estimated effective doses of 134Cs and 137Cs agreed well with those estimated through market basket and food-duplicate surveys. The average thyroid equivalent doses due to ingestion of 131I for adults were 840 µSv (Case 1) and 2700 µSv (Case 2) in Fukushima City, 370 µSv in Tokyo, and 16 µSv in Osaka. The average effective doses due to 134Cs and 137Cs were 19, 120, 6.1, and 1.9 µSv, respectively. The doses estimated in this study were much lower than values reported by the World Health Organization and the United Nations Scientific Committee on the Effects of Atomic Radiation, whose assessments lacked validation and full consideration of regional trade in foods, highlighting the importance of including regional trade. The 95th percentile effective doses were 2-3 times the average values. Lifetime attributable risks (LARs) of thyroid cancers due to ingestion were 1.7-37×10-6 (Case 1) and5.6-79×10-6 (Case 2) in Fukushima City, 0.73-13×10-6 in Tokyo, and 0.04-0.49×10- 6 in Osaka. The contributions of LARs of thyroid cancers due to ingestion were 5.4%-11% of all exposure (Case 1) and 11%-25% (Case 2) in Fukushima City [corrected].

  11. Episodic trihalomethane species and levels in tap water at a start of operation of advanced treatment in Osaka Prefectural water supplies.

    PubMed

    Yamamoto, Kohji; Mori, Yoshiaki

    2009-11-01

    Dramatic changes in trihalomethanes of tap water caused by decreasing the chlorine dose from to break-point to zero at a pre-chlorination could be found during several years from starting the advanced treatment in Osaka Prefectural water utilities (from 1998 to 2002). In 1998 (break-point chlorination), chloroform was predominant (an average of 14.3 microg/L) and bromodichloromethane (5.96 microg/L), dibromochloromethane (4.19 microg/L) and bromoform (1.06 microg/L) were in the decreasing order. In contrast, in 1999 (chloramination), dibromochloromethane and bromodichloromethane were abundant trihalomethanes (6.61 and 5.72 microg/L) and followed by chloroform (4.14 microg/L) and bromoform (1.41 microg/L). Trihalomethane distribution in 2002 (non-chlorination) was almost the same as that in 1999.

  12. Evidence of infection with Leptospira interrogans and spotted fever group rickettsiae among rodents in an urban area of Osaka City, Japan.

    PubMed

    Shimizu, Kenta; Isozumi, Rie; Takami, Kazutoshi; Kimata, Isao; Shiokawa, Kanae; Yoshimatsu, Kumiko; Tsuda, Yoshimi; Nishio, Sanae; Arikawa, Jiro

    2017-07-19

    We examined 33 rodents captured in an urban area of Osaka City, Japan for IgG antibodies against Seoul virus, severe fever with thrombocytopenia syndrome virus, hepatitis E virus, Leptospira interrogans, Yersinia pestis, spotted fever, typhus and scrub typhus group rickettsiae. We found that 3 (9.1%) and 1 (3.0%) of the 33 rodents had antibodies against L. interrogans and spotted fever group rickettsiae, respectively. DNAs of leptospires were detected from 2 of the 3 seropositive rodents, but DNA of rickettsia was not detected. Phylogenetic analysis and multiple locus sequence typing revealed that the 2 leptospires were L. interrogans belonging to a novel sequence type. There is a potential risk for acquiring rodent-borne zoonotic pathogens even in cities in developed countries.

  13. Trends of allergic symptoms in school children: large-scale long-term consecutive cross-sectional studies in Osaka Prefecture, Japan.

    PubMed

    Yura, Akiko; Kouda, Katsuyasu; Iki, Masayuki; Shimizu, Tadahiko

    2011-09-01

    Trends in the prevalence rates of allergic symptoms in children have been discussed extensively, but it remains uncertain which symptoms increase or decrease over time owing to the lack of large-scale long-term consecutive cross-sectional studies performed on a representative population of children. To clarify the trends in the prevalence rates of allergic symptoms in Japanese children. Total population questionnaire surveys were conducted 15 times from 1975 to 2006 for all children attending public elementary schools in Osaka Prefecture, Japan, with the number of subjects ranging from 460,000 to 900,000. Parents of the children completed the questionnaire about allergic symptoms and other symptoms, including wheeze, physician-diagnosed atopic dermatitis, rhinitis, and itching eyes. Response rates were consistently over 90%. The prevalence of wheezing was constant until 1983, then increased from 1983 until 1993, then stabilized at about 4.4%. The lifetime prevalence of atopic dermatitis increased to 24% by 1993, and then decreased. The prevalence of rhinitis increased to 25% by 2003, whereas the prevalence of non-seasonal symptoms plateaued from 1993 on at 11% and vernal symptoms increased. The prevalence of itching eyes continued to increase to 21% in 2006, and vernal symptoms increased sharply. In Osaka Prefecture, Japan, the turning point when the prevalence of wheezing in schoolchildren had begun to increase was 1983. And the turning point when the increase in the prevalence of wheezing, atopic dermatitis, and non-seasonal allergic rhinitis turned to decrease or constant was 1993. The prevalence of rhinitis and itching eyes in spring was still increasing in 2006. © 2011 John Wiley & Sons A/S.

  14. Factors associated with the difficulty in hospital acceptance at the scene by emergency medical service personnel: a population-based study in Osaka City, Japan.

    PubMed

    Katayama, Yusuke; Kitamura, Tetsuhisa; Kiyohara, Kosuke; Iwami, Taku; Kawamura, Takashi; Hayashida, Sumito; Yoshiya, Kazuhisa; Ogura, Hiroshi; Shimazu, Takeshi

    2016-10-26

    To investigate the association between the difficulty in hospital acceptance at the scene by emergency medical service (EMS) personnel and prehospital demographic factors and reasons for EMS calls. A retrospective, observational study. Osaka City, Japan. A total of 100 649 patients transported to medical institutions by EMS from January 2013 to December 2013. The definition of difficulty in hospital acceptance at the scene was EMS personnel making ≥5 phone calls to medical institutions until a decision to transport was determined. Multivariable analysis was used to assess the relationship between difficulty in hospital acceptance and prehospital factors and reasons for EMS calls. Multivariable analysis showed the elderly, foreigners, loss of consciousness, holiday/weekend, and night-time to be positively associated with difficulty in hospital acceptance at the scene. As reasons for EMS calls, gas poisoning (adjusted OR 3.281, 95% CI 1.201 to 8.965), trauma by assault (adjusted OR 2.662, 95% CI 2.390 to 2.966), self-induced drug abuse/gas poisoning (adjusted OR 4.527, 95% CI 3.921 to 5.228) and self-induced trauma (adjusted OR 1.708, 95% CI 1.369 to 2.130) were positively associated with the difficulty in hospital acceptance at the scene. Ambulance records in Osaka City showed that certain prehospital factors such as night-time were positively associated with difficulty in hospital acceptance at the scene, and reasons for EMS calls, such as self-induced drug abuse/gas poisoning, were also positive predictors for difficulty in hospital acceptance at the scene. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  15. Effectiveness of prehospital Magill forceps use for out-of-hospital cardiac arrest due to foreign body airway obstruction in Osaka City.

    PubMed

    Sakai, Tomohiko; Kitamura, Tetsuhisa; Iwami, Taku; Nishiyama, Chika; Tanigawa-Sugihara, Kayo; Hayashida, Sumito; Nishiuchi, Tatsuya; Kajino, Kentaro; Irisawa, Taro; Shiozaki, Tadahiko; Ogura, Hiroshi; Tasaki, Osamu; Kuwagata, Yasuyuki; Hiraide, Atsushi; Shimazu, Takeshi

    2014-09-04

    Although foreign body airway obstruction (FBAO) accounts for many preventable unintentional accidents, little is known about the epidemiology of FBAO patients and the effect of forceps use on those patients. This study aimed to assess characteristics of FBAO patients transported to hospitals by emergency medical service (EMS) personnel, and to verify the relationship between prehospital Magill forceps use and outcomes among out-of-hospital cardiac arrests (OHCA) patients with FBAO. We retrospectively reviewed ambulance records of all patients who suffered FBAO, and were treated by EMS in Osaka City from 2000 through 2007, and assessed the characteristics of those patients. We also performed a multivariate logistic-regression analysis to assess factors associated with neurologically favorable survival among bystander-witnessed OHCA patients with FBAO in larynx or pharynx. A total of 2,354 patients suffered from FBAO during the study period. There was a bimodal distribution by age among infants and old adults. Among them, 466 (19.8%) had an OHCA when EMS arrived at the scene, and 344 were witnessed by bystanders. In the multivariate analysis, Magill forceps use for OHCA with FBAO in larynx or pharynx was an independent predictor of neurologically favorable survival (16.4% [24/146] in the Magill forceps use group versus 4.3% [4/94] in the non-use group; adjusted odds ratio, 3.96 [95% confidence interval, 1.21-13.00], p = 0.023). From this large registry in Osaka, we revealed that prehospital Magill forceps use was associated with the improved outcome of bystander-witnessed OHCA patients with FBAO.

  16. Out-of-hospital cardiac arrests during exercise among urban inhabitants in Japan: Insights from a population-based registry of Osaka City.

    PubMed

    Kiyohara, Kosuke; Sado, Junya; Matsuyama, Tasuku; Nishiyama, Chika; Kobayashi, Daisuke; Kiguchi, Takeyuki; Hayashida, Sumito; Kitamura, Yuri; Sobue, Tomotaka; Nakata, Ken; Iwami, Taku; Kitamura, Tetsuhisa

    2017-08-01

    The patient characteristics, pre-hospital interventions, and outcomes of out-of-hospital cardiac arrests (OHCA) occurring during exercise, have not been sufficiently investigated among the general population. OHCA data from 2009 to 2015 were obtained from the population-based OHCA registry in Osaka City, Japan. Patients who suffered OHCA, which occurred during exercise before the arrival of emergency medical service personnel, were included. The primary endpoint was one-month survival with a favourable neurological outcome after OHCA, defined using the Glasgow-Pittsburgh cerebral performance category scale 1 or 2. During the 7-year study period, 16,278 OHCAs were observed, and 52 (0.3%) occurred during exercise (male, n=41 [79%]; median age, 62 years). These incidents occurred mainly during running activities (n=14), followed by swimming (n=8), dance/social dance (n=6), tennis (n=4), and weight training (n=3). Within these exercise-related OHCAs, 47 (90%) were of cardiac origin, 45 (87%) were bystander-witnessed cardiac arrests, 49 (94%) received bystander-initiated cardiopulmonary resuscitation, and 30 (57%) received public-access defibrillation (PAD). Overall, 56% (29/52) had one-month survival with a favourable neurological outcome after OHCA, which was significantly higher among OHCAs of cardiac origin with PAD (77%, 23/30) than among those of cardiac origin without PAD (35%, 6/17) and among those of non-cardiac origin (0%, 0/5) (p<0.001). In Osaka, OHCAs during exercise represented a small subset of the overall OHCA burden, but occurred during a wide variety of exercise activities. Patients with OHCA of cardiac origin had a good prognosis, and PAD played an important role in improving patient outcomes. Copyright © 2017 Elsevier B.V. All rights reserved.

  17. Impact of the number of on-scene emergency life-saving technicians and outcomes from out-of-hospital cardiac arrest in Osaka City.

    PubMed

    Kajino, Kentaro; Kitamura, Tetsuhisa; Iwami, Taku; Daya, Mohamud; Ong, Marcus Eng Hock; Nishiyama, Chika; Sakai, Tomohiko; Tanigawa-Sugihara, Kayo; Hayashida, Sumito; Nishiuchi, Tatsuya; Hayashi, Yasuyuki; Hiraide, Atsushi; Shimazu, Takeshi

    2014-01-01

    In Japan, ambulance staffing for cardiac arrest responses consists of a 3-person unit with at least one emergency life-saving technician (ELST). Recently, the number of ELSTs on ambulances has increased since it is believed that this improves the quality of on-scene care leading to better outcomes from out-of-hospital cardiac arrest (OHCA). The objective of this study was to evaluate the association between the number of on-scene ELSTs and OHCA outcome. This was a prospective cohort study of all bystander-witnessed OHCA patients aged ≥ 18 years in Osaka City from January 2005 to December 2007 using on an Utstein-style database. The primary outcome measure was one-month survival with favorable neurological outcome defined as a cerebral performance category ≤ 2. Multivariable logistic regression model were used to assess the contribution of the number of on-scene ELSTs to the outcome after adjusting for confounders. Of the 2408 bystander-witnessed OHCA patients, one ELST group was present in 639 (26.5%), two ELST were present in 1357 (56.4%), and three ELST group in 412 (17.1%). The three ELST group had a significantly higher rate of one-month survival with favorable neurological outcome compared with the one ELST group (8.0% versus 4.5%, adjusted OR 2.26, 95% CI 1.27-4.04), while the two ELST group did not (5.4% versus 4.5%, adjusted OR 1.34, 95% CI 0.82-2.19). Compared with the one on-scene ELST group, the three on-scene ELST group was associated with the improved one-month survival with favorable neurological outcome from OHCA in Osaka City. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

  18. Socioeconomic inequalities in cancer survival: a population-based study of adult patients diagnosed in Osaka, Japan, during the period 1993-2004.

    PubMed

    Ito, Yuri; Nakaya, Tomoki; Nakayama, Tomio; Miyashiro, Isao; Ioka, Akiko; Tsukuma, Hideaki; Rachet, Bernard

    2014-10-01

    Long-term recession of the Japanese economy during the 1990s led to growing social inequalities whilst health inequalities also appeared. The 2007 National Cancer Control Program of Japan targeted "equalisation of cancer medical services", but the system to monitor health inequalities was still inadequate. We aimed to measure socioeconomic inequalities in cancer survival in Japan. We analysed 13 common invasive, primary, malignant tumours diagnosed from 1993 to 2004 and registered by the population-based Cancer Registry of Osaka Prefecture. An ecological socioeconomic deprivation index based on small area statistics, divided into quintile groups, was linked to patients according to their area of residence at the time of diagnosis. We estimated one-, five-year and conditional five-year net survival by sex, period of diagnosis (1993-1996/1997-2000/2001-2004) and deprivation group. Changes in survival over time, deprivation gap in survival, and change in deprivation gap were estimated at one and five years after diagnosis using variance-weighted least square regression. The deprivation gap in one-year net survival was narrower than in five-year net survival and conditional five-year survival. During the study period, there was no change in deprivation gap, except for reductions for pancreas (men) and stomach (women), and an increase for lung (men) in one-year survival. We observed a linear association between level of survival and deprivation gap at five years and conditional five years, but no association at one-year survival. A wide deprivation gap in survival was observed in most of the adult, solid, malignant tumours, within the universal healthcare system in Japan. Overall, cancer survival improved in Osaka without any widening of inequalities in cancer survival in 1993-2004, shortly after the long-term economic recession and deep modifications in the social and work environments in Japan. The longer term impact of the recession on inequalities in cancer survival

  19. Factors associated with the difficulty in hospital acceptance at the scene by emergency medical service personnel: a population-based study in Osaka City, Japan

    PubMed Central

    Katayama, Yusuke; Kitamura, Tetsuhisa; Kiyohara, Kosuke; Iwami, Taku; Kawamura, Takashi; Hayashida, Sumito; Yoshiya, Kazuhisa; Ogura, Hiroshi; Shimazu, Takeshi

    2016-01-01

    Objectives To investigate the association between the difficulty in hospital acceptance at the scene by emergency medical service (EMS) personnel and prehospital demographic factors and reasons for EMS calls. Design A retrospective, observational study. Setting Osaka City, Japan. Participants A total of 100 649 patients transported to medical institutions by EMS from January 2013 to December 2013. Primary outcome measurements The definition of difficulty in hospital acceptance at the scene was EMS personnel making ≥5 phone calls to medical institutions until a decision to transport was determined. Multivariable analysis was used to assess the relationship between difficulty in hospital acceptance and prehospital factors and reasons for EMS calls. Results Multivariable analysis showed the elderly, foreigners, loss of consciousness, holiday/weekend, and night-time to be positively associated with difficulty in hospital acceptance at the scene. As reasons for EMS calls, gas poisoning (adjusted OR 3.281, 95% CI 1.201 to 8.965), trauma by assault (adjusted OR 2.662, 95% CI 2.390 to 2.966), self-induced drug abuse/gas poisoning (adjusted OR 4.527, 95% CI 3.921 to 5.228) and self-induced trauma (adjusted OR 1.708, 95% CI 1.369 to 2.130) were positively associated with the difficulty in hospital acceptance at the scene. Conclusions Ambulance records in Osaka City showed that certain prehospital factors such as night-time were positively associated with difficulty in hospital acceptance at the scene, and reasons for EMS calls, such as self-induced drug abuse/gas poisoning, were also positive predictors for difficulty in hospital acceptance at the scene. PMID:27798040

  20. Calibration of the radiation monitors from DESY and SPring-8 at the quasi-mono-energetic neutron beams using 100 and 300 MeV 7Li(p,n) reaction at RCNP in Osaka Japan in November 2014

    NASA Astrophysics Data System (ADS)

    Leuschner, Albrecht; Asano, Yoshihiro; Klett, Alfred

    2017-09-01

    At the ring cyclotron facility of the Research Center for Nuclear Physics (RCNP) Osaka University, Osaka, Japan a series of measurement campaigns had been continued with quasi mono-energetic neutron beams in November 2014. A 7Li target was bombarded with 100 and 300 MeV protons and the generated neutron beams were directed into a long time-of-flight tunnel at 0 and 25 degrees deflection angle with respect to the proton beam. At a distance of 41 m the cross section of the neutron beam was large enough for the illumination of square meter sized objects like extended range rem-counters. The research institutes SPring-8/RIKEN, Japan, and DESY, Germany, participated in this campaign for the calibration of 4 different types of active ambient dose rate monitors: LB 6411, LB 6411-Pb, LB 6419 and LB 6420. The measurements of their responses are reported and compared with the calculated values.

  1. Large-Scale Molecular Gas Survey in 12CO, 13CO and C18O (J = 2-1) with the Osaka 1.85m mm-submm Telescope

    NASA Astrophysics Data System (ADS)

    Onishi, Toshikazu; Nishimura, Atsushi; Tokuda, Kazuki; Harada, Ryohei; Dobashi, Kazuhito; Shimoikura, Tomomi; Kimura, Kimihiro; Ogawa, Hideo

    We have developed a new mm-submm telescope with a diameter of 1.85 m (hereafter, Osaka 1.85-m telescope) installed at the Nobeyama Radio Observatory. The scientific goal is to precisely reveal physical properties of molecular clouds in the Galaxy by obtaining a large-scale distribution of molecular gas, which also can be compared with large-scale observations in various wavelengths. The target frequency is ~230 GHz; simultaneous observations in J = 2-1 lines of 12CO, 13CO and C18O are achieved with a beam size (HPBW) of 2.7 arcmin. Here we present the progress of observations and the scientific results obtained by Osaka 1.85-m telescope. We note that these J = 2-1 data of the Galactic molecular clouds will be precious for the comparison with those of extra-galactic ones that will be obtained with the ALMA with the comparable spatial resolutions.

  2. Secular variation between 5 and 10c CE in Japan: remeasurements of 2000 samples collected between 1960-70's from Sueki earthenware kilns in Osaka.

    NASA Astrophysics Data System (ADS)

    Shibuya, H.; Mochizuki, N.; Hatakeyama, T.

    2015-12-01

    In Japan, archeomagnetic measurements are vigorously developed for years, though it is not well known to paleomagnetism community in english. One of the works is massive archeomagnetic study of Suemura kiln group carried out in Osaka University in 1960's to early 70's. More than 500 kilns were excavated in Sakai city and vicinities, Osaka Prefecture, Japan. The kiln group is called as Suemura Kilns, and are for Sueki earthenware of 5c to 10c CE. About 300 kilns were sampled and most of the samples were measured at the time, and the results are reported in e.g. Hirooka (1971) and Shibuya (1980). However, the results have significant scatter in direction, which may be due to the limitation of old astatic magnetometer measurements and handwriting graphic determination of magnetic direction, and/or the lack of demagnetization. We recently inherited many of those samples and remeasured them with spinner magnetometer applying alternation field demagnetization (afd). The magnetizations are generally very stable, as usual as other archeomagnetic samples, and afd does not change the magnetic direction mostly. However, significant number of sites show large scatter in magnetic directions, which might be due to the wrong identification of kiln floor or disturbance at the time of collapsing or excavation. Taking kilns of α95<4o, we recovered 131 paleomagnetic directions. Although third of them are dated by pottery shape chronology, the range of each pottery style is not precisely known and the relation of the baked floor and the potteries excavated around kilns are not always clear. The carbon dating of those kilns are very scares. Thus we first try to draw secular variation curve in declination-inclination plot. With the rough ages of those kilns, it is pretty easy to draw the SVC. It is also numerically determined taking the distance of each direction from nearest point in SVC and the velocity change of the SVC as penalty function, within a couple of degrees in the error

  3. Descriptive epidemiological study of vaginal cancer using data from the Osaka Japan population-based cancer registry: Long-term analysis from a clinical viewpoint.

    PubMed

    Yagi, Asami; Ueda, Yutaka; Kakuda, Mamoru; Tanaka, Yusuke; Egawa-Takata, Tomomi; Morimoto, Akiko; Iwamiya, Tadashi; Matsuzaki, Shinya; Kobayashi, Eiji; Yoshino, Kiyoshi; Fukui, Keisuke; Ito, Yuri; Nakayama, Tomio; Kimura, Tadashi

    2017-08-01

    Vaginal cancer is such a rare tumor that epidemiological and clinical information for it is based mainly on studies of small numbers of cases. The aim of the present study was to perform a descriptive epidemiological analysis of vaginal cancer using a significantly larger population-based dataset from the Japanese Osaka Cancer Registry.The age-standardized incidence of vaginal cancer per 1,000,000 persons, from 1976 to 2010, was calculated and examined for trends. Relative-survival analysis was applied to estimate a more up-to-date 10-year period calculation, using data from recently followed-up patients. The conditional 5-year survival of patients who survived for 0 to 5 years after diagnosis was calculated.A total of 481 cases of vaginal cancer were registered in Osaka during the 35-year period from 1976 to 2010. The age-adjusted incidence rate has significantly and consistently decreased over this time [annual percent change (APC) = -1.29, 95% confidence interval (95% CI): -0.3 ∼ -2.2]; however, due to significant population aging, the raw incidence of vaginal cancer appeared to have been increasing. The 10-year relative survival of patients with surgery-based treatments was comparable to that of radiation-based treatments, implying that surgery and radiotherapy provide similar therapeutic benefits (P = .98). The 10-year relative survival was not significantly different during the period of 1976 to 2000 compared with the period of 2001 to 2008, although there has been, in the latter period, a tendency for improvement of long-term survival, especially for survival longer than 5 years. The longer the time after diagnosis, the higher the conditional 5-year relative-survival at 0 to 4 years after diagnosis.The age-adjusted incidence of vaginal cancer has decreased since 1976. Regrettably, the 10-year survival rate did not similarly improve, and it remained stable during the period from 2001 to 2008, compared with the period from 1976 to 2000, indicating

  4. Epidemiology and outcome of adult out-of-hospital cardiac arrest of non-cardiac origin in Osaka: a population-based study.

    PubMed

    Kitamura, Tetsuhisa; Kiyohara, Kosuke; Sakai, Tomohiko; Iwami, Taku; Nishiyama, Chika; Kajino, Kentaro; Nishiuchi, Tatsuya; Hayashi, Yasuyuki; Katayama, Yusuke; Yoshiya, Kazuhisa; Shimazu, Takeshi

    2014-12-22

    To evaluate epidemiological characteristics of out-of-hospital cardiac arrests (OHCAs) by detailed non-cardiac cause and factors associated with the outcomes after OHCAs of non-cardiac origin. A prospective, population-based observational study. The Utstein Osaka Project. 14,164 adult patients aged ≥20 years old with OHCAs due to non-cardiac origin who were resuscitated by emergency-medical-service personnel or bystanders, and then were transported to medical institutions from January 2005 to December 2011. One-month survival after OHCA. Multiple logistic regression analysis was used to assess factors that were potentially associated with the outcome. During the study period, the 1-month survival rate was 5.3% (755/14,164). The proportion of 1-month survival was 6.2% (510/8239) in external causes, 6.5% (94/1148) in respiratory diseases, 0.8% (11/1309) in malignant tumours, 4.9% (55/1114) in strokes and 4.1% (85/2054) in others. As for external causes, the proportion of 1-month survival was 14.3% (382/2670) in asphyxia, 4.2% (84/1999) in hanging, 0.7% (9/1300) in fall, 1.1% (12/1062) in drowning, 1.6% (12/765) in traffic injury, 3.7% (7/187) in drug overuse and 1.6% (4/256) in unclassified external causes. In a multivariate analysis, adults aged <65 years old with arrests witnessed by bystanders, with normal activities of daily living before the arrests, having ventricular fibrillation arrests, having arrests in public places, intravenous fluid levels and early Emergency Medical Service response time were significant predictors for 1-month outcome after OHCAs of non-cardiac origin. The proportion of 1-month survival of all OHCAs of non-cardiac origin did not significantly increase (from 4.3% (86/2023) in 2005 to 4.9% (105/2126) in 2011) and the adjusted OR for one-increment of year was 1.01 (95% CI 0.97 to 1.06). From a large OHCA registry in Osaka, we demonstrated that 1-month survival after OHCAs of non-cardiac origin was poor and stable. Published by the BMJ

  5. Neutron spectrometry and dosimetry in 100 and 300 MeV quasi-mono-energetic neutron field at RCNP, Osaka University, Japan

    NASA Astrophysics Data System (ADS)

    Mares, Vladimir; Trinkl, Sebastian; Iwamoto, Yosuke; Masuda, Akihiko; Matsumoto, Tetsuro; Hagiwara, Masayuki; Satoh, Daiki; Yashima, Hiroshi; Shima, Tatsushi; Nakamura, Takashi

    2017-09-01

    This paper describes the results of neutron spectrometry and dosimetry measurements using an extended range Bonner Sphere Spectrometer (ERBSS) with 3He proportional counter performed in quasi-mono-energetic neutron fields at the ring cyclotron facility of the Research Center for Nuclear Physics (RCNP), Osaka University, Japan. Using 100 MeV and 296 MeV proton beams, neutron fields with nominal peak energies of 96 MeV and 293 MeV were generated via 7Li(p,n)7Be reactions. Neutrons produced at 0° and 25° emission angles were extracted into the 100 m long time-of-flight (TOF) tunnel, and the energy spectra were measured at a distance of 35 m from the target. To deduce the corresponding neutron spectra from thermal to the nominal maximum energy, the ERBSS data were unfolded using the MSANDB unfolding code. At high energies, the neutron spectra were also measured by means of the TOF method using NE213 organic liquid scintillators. The results are discussed in terms of ambient dose equivalent, H*(10), and compared with the readings of other instruments operated during the experiment.

  6. Long-term simulation of human exposure to atmospheric perfluorooctanoic acid (PFOA) and perfluorooctanoate (PFO) in the Osaka urban area, Japan.

    PubMed

    Niisoe, Tamon; Harada, Kouji H; Ishikawa, Hirohiko; Koizumi, Akio

    2010-10-15

    A publicly available atmospheric transport model, the Weather Research and Forecasting Chemistry Model ( http://ruc.noaa.gov/wrf/WG11/ ), was used to simulate atmospheric perfluorooctanoic acid (PFOA) and perfluorooctanoate (PFO) emitted from a point source in the Osaka urban area (also known as Keihanshin), Japan. The time period of the simulation was from 1983 to 2008. The modeled air concentrations were highly correlated (r = 0.91) with the observed air concentrations. Intake levels by inhalation of simulated air concentrations and through the gastrointestinal tract as estimated by the food duplicate method were input to a pharmacokinetic model of the human body to simulate serum concentrations of PFOA and PFO (PFO(A)). For validation of the atmospheric model, simulated values were compared with those observed in serum samples. The simulated values generally agreed with those observed in serum samples from residents of the Keihanshin area (r = 0.93). It was confirmed that the atmospheric model was generally capable of projecting features of atmospheric PFO(A) as well as serum concentrations of PFO(A) in this case. The results indicated a dominant contribution of the atmospheric component to serum PFO(A) in humans near the point source in the Keihanshin area. In 2008, that contribution was about 70%.

  7. Future projections of labor hours based on WBGT for Tokyo and Osaka, Japan, using multi-period ensemble dynamical downscale simulations

    NASA Astrophysics Data System (ADS)

    Suzuki-Parker, Asuka; Kusaka, Hiroyuki

    2016-02-01

    Following the heatstroke prevention guideline by the Ministry of Health, Labor, and Welfare of Japan, "safe hours" for heavy and light labor are estimated based on hourly wet-bulb globe temperature (WBGT) obtained from the three-member ensemble multi-period (the 2000s, 2030s, 2050s, 2070s, and 2090s) climate projections using dynamical downscaling approach. Our target cities are Tokyo and Osaka, Japan. The results show that most of the current climate daytime hours are "light labor safe,", but these hours are projected to decrease by 30-40 % by the end of the twenty-first century. A 60-80 % reduction is projected for heavy labor hours, resulting in less than 2 hours available for safe performance of heavy labor. The number of "heavy labor restricted days" (days with minimum daytime WBGT exceeding the safe level threshold for heavy labor) is projected to increase from ~5 days in the 2000s to nearly two-thirds of the days in August in the 2090s.

  8. Trends in 'cure' fraction from colorectal cancer by age and tumour stage between 1975 and 2000, using population-based data, Osaka, Japan.

    PubMed

    Ito, Yuri; Nakayama, Tomio; Miyashiro, Isao; Sugimoto, Tomoyuki; Ioka, Akiko; Tsukuma, Hideaki; Abdel-Rahman, Manar E; Rachet, Bernard

    2012-10-01

    Since the 1960s, Japan has experienced a striking increase in the incidence of colorectal cancer, now the second most common cancer in the country. Meanwhile, the management of colorectal cancer has changed dramatically with the implementation of, for example, screening, endoscopy and adjuvant chemotherapy. It is therefore of interest to monitor the long-term trends in population 'cure' in Japan. We analysed 33 885 colorectal cancer cases diagnosed between 1975 and 2000 in Osaka. We applied the multivariable mixture cure model to estimate cure fraction and median survival time (MST) for 'uncured' patients, by sex, age, stage, period at diagnosis and subsite. For colon cancer, the cure fraction increased by about 25%, while MST for the uncured was prolonged from 8 to 12 months. The cure fraction was 5% higher in men than in women, while MST was similar in both. The cure fraction also increased for localized and regional tumours. For rectal cancer, the cure fraction increased by about 25-30%, but remained lower than for colon cancer. From the late 1970s, the cure fraction for colorectal cancer increased dramatically due to better management of detection and care for colorectal cancer. This improvement was obtained at the cost of shorter MST for uncured patients.

  9. Dose Measurements through the Concrete and Iron Shields under the 100 to 400 MeV Quasi-Monoenergetic Neutron Field (at RCNP, Osaka Univ.)

    NASA Astrophysics Data System (ADS)

    Nakane, Yoshihiro; Iwamoto, Yosuke; Hagiwara, Masayuki; Iwase, Hiroshi; Sato, Tatsuhiko; Masuda, Akihiko; Matsumoto, Tetsuro; Nunomiya, Tomoya; Yashima, Hiroshi; Satoh, Daiki; Nakashima, Hiroshi; Shima, Tatsushi; Tamii, Atsushi; Hatanaka, Kichiji; Nakamura, Takashi

    2017-09-01

    Shielding benchmark experiments are useful to verify the accuracy of calculation methods for the radiation shielding designs of high-energy accelerator facilities. In the present work, the benchmark experiments were carried out for 244- and 387-MeV quasi-monoenergetic neutron field at RCNP of Osaka University. Neutron dose rates through the test shields, 100-300 cm thick concrete and 40-100 cm thick iron, were measured by four kinds of neutron dose equivalent monitors, three kinds of wide-energy range monitors applied to high-energy neutron fields above 20 MeV and a conventional type rem monitor for neutrons up to 20 MeV, placed behind the test shields. Measured dose rates were compared one another. Measured results with the wide-energy range monitors were in agreement one another for both the concrete and the iron shields. For the conventional type rem monitor, measured results are smaller than those with the wide-energy range monitors for the concrete shields, while that are in agreements for the iron shields. The attenuation lengths were obtained from the measurements. The lengths from all the monitors are in agreement on the whole, though some differences are shown. These results are almost same as those from others measured at several hundred MeV neutron fields.

  10. Prevalence of Diarrheagenic Escherichia coli in Foods and Fecal Specimens Obtained from Cattle, Pigs, Chickens, Asymptomatic Carriers, and Patients in Osaka and Hyogo, Japan.

    PubMed

    Wang, Lili; Zhang, Shaobo; Zheng, Dongming; Fujihara, Sami; Wakabayashi, Akiyo; Okahata, Kazuyuki; Suzuki, Masakazu; Saeki, Atsunori; Nakamura, Hiromi; Hara-Kudo, Yukiko; Kage-Nakadai, Eriko; Nishikawa, Yoshikazu

    2017-07-24

    The source and routes of diarrheagenic Escherichia coli (DEC) remain poorly understood. To investigate the involvement of domestic animals in the dissemination of DEC, the prevalence of DEC in foods and fecal specimens from cattle, pigs, chickens, healthy carriers, and patients in Osaka and Hyogo, Japan was investigated using a multiplex real-time Polymerase Chain Reaction assay. The most abundant virulence genes were astA and eae, which had a prevalence 46.8% and 27.4%, respectively. Additionally, stx1 (26.6%) and stx2 (45.9%) were prevalent in cattle feces, while est (8.5%) and elt (7.6%) were prevalent in pig feces. afaB was the second-most prevalent gene in patients and healthy carriers, and it had detection rates of 5.1% and 8.1%, respectively. In contrast, afaB was not detected in animal feces or foods, except for three porcine fecal samples. The aggR gene was more prevalent in humans than in foods or animal feces. Both Shiga toxin-producing E. coli and atypical enteropathogenic E. coli carried by cattle may be sources for diarrheal diseases in humans. Pigs may be a source for human enterotoxigenic E. coli infections, whereas humans are expected to be the reservoir for diffusely adhering E. coli, enteroaggregative E. coli, and enteroinvasive E. coli.

  11. Comparison of Air Pollution in Metropolises in China (Beijing) and Japan (Osaka and Nagoya) on the Basis of the Levels of Contaminants and Mutagenicity.

    PubMed

    Coulibaly, Souleymane; Minami, Hiroki; Abe, Maho; Furukawa, Nami; Ono, Ryo; Hasei, Tomohiro; Toriba, Akira; Tang, Ning; Hayakawa, Kazuichi; Funasaka, Kunihiro; Asakawa, Daichi; Ikemori, Fumikazu; Watanabe, Masanari; Honda, Naoko; Wakabayashi, Keiji; Watanabe, Tetsushi

    2016-01-01

    Public concern regarding the transport of air pollutants from mainland East Asia to the leeward area by the prevailing westerlies in spring and winter monsoon has been growing in recent years. We collected total suspended particle (TSP) in Beijing, a metropolis of China located windward of Japan, in spring (late February 2011-May 2011) and in winter (November 2012-early February 2013), then analyzed metals, ions, and organic compounds and mutagenicity, and compared the pollution levels with samples collected at two Japanese metropolises (Osaka and Nagoya) during the same periods. The medians of concentration of TSP and other factors in Beijing were much larger than those in the Japanese metropolises. Especially, the concentrations of polycyclic aromatic hydrocarbons (PAHs) were remarkably high in Beijing in winter, and the median of total PAHs concentration in Beijing was 62-63 times larger than that in the Japanese sites. The mutagenicity of TSP from Beijing toward Salmonella typhimurium YG1024, with and without a mammalian metabolic system (S9 mix), was 13-25 times higher than that from the Japanese sites in winter. These results suggest that air pollution levels in Beijing are very high compared with those at the two Japanese metropolises we evaluated. The diagnostic ratios of PAHs and nitrated polycyclic aromatic hydrocarbons (NPAHs) suggest that the major sources of PAHs and NPAHs in Beijing are different from those at the two Japanese sites in winter, and that the major source in Beijing is coal/biomass combustion.

  12. Effects of desiccation and salinity on the outbreak of a green tide of Ulva pertusa in a created salt marsh along the coast of Osaka Bay, Japan

    NASA Astrophysics Data System (ADS)

    Yamochi, Susumu

    2013-01-01

    Field surveys and laboratory experiments were conducted to examine the effect of desiccation and salinity on the outbreak of a green tide of Ulva pertusa at Osaka Nanko bird sanctuary. Reduction of biomass of Ulva spp. was observed at stations where the exposure rate to air was from 30 to 40%. In addition, the exposure rate of 30-40% to air showed no negative impacts on the biomass of benthic microalgae, infauna and non-motile epibenthos. Laboratory experiments revealed that photosynthetic activity of U. pertusa decreased when exposed to air for 4-7 h at 25-35 °C. Salinity decreases from 30 to 25 or 20 accompanied with exposure to air drastically reduced the rate of photosynthesis of this species. These results suggest the possibility of controlling a green tide of U. pertusa without serious physico-ecological damage to benthic microalgae, infauna and non-motile epibenthos by a combination of exposure to air with low salinity.

  13. Spatial and temporal trends in perfluorooctanoic and perfluorohexanoic acid in well, surface, and tap water around a fluoropolymer plant in Osaka, Japan.

    PubMed

    Shiwaku, Yoko; Lee, Pureum; Thepaksorn, Phayong; Zheng, Bo; Koizumi, Akio; Harada, Kouji H

    2016-12-01

    This study was conducted to clarify the spatial distributions of perfluorooctanoic acid (PFOA) and perfluorohexanoic acid (PFHxA) in well, surface and tap water around a fluoropolymer plant in Osaka between 2003 and 2016 and to predict the fate of those chemicals in these aquatic environments. We analyzed 44 well, six surface and six tap water samples collected within a 5 km radius of the plant. The PFOA concentrations in well water ranged from 45.2 to 7440 ng/L (median = 240 ng/L), while PFHxA concentrations ranged from 9.68 to 970 (median = 45.4 ng/L) in 2015-2016. The concentration of other perfluoroalkyl carboxylic acids were lower than PFOA and PFHxA in well water. Fixed-point observation showed that the levels of PFOA decreased greatly over the last few decades, whereas those of PFHxA increased in both well and surface water. Further monitoring and investigation are suggested to understand PFOA and PFHxA contamination and fate in the environment, as well as their potential for human exposure in this region. Copyright © 2016 Elsevier Ltd. All rights reserved.

  14. Possible Linkage between Geomagnetic Field, Temperature and Monsoon: Implication of High-Resolution Magnetic and Climatic Data from a Sediment Core in Osaka Bay, Japan

    NASA Astrophysics Data System (ADS)

    Kitaba, I.; Hyodo, M.; Katoh, S.; Dettman, D. L.; Sato, H.

    2013-12-01

    Observed correlation between galactic cosmic ray (CR) flux and cloud cover suggests that variations in geomagnetic field intensity could change climate through modulation of CR flux. Kitaba et al. (2013) reported a pollen-based climate cooling that coincided with a large decrease in field intensity during the Matuyama-Brunhes and Lower Jaramillo geomagnetic polarity reversals using a sediment core from Osaka Bay, Japan. The cooling event is not attributed to orbital forcing, but to the geomagnetic field intensity variation through modulation of CR flux. If the geomagnetic field intensity disturbs global heat balance, it may further affect monsoon and/or precipitation. Our pollen-based climate data show that during the cooling the difference in mean temperature between the warmest and coldest months (indicator of land-ocean temperature gradient) increased, and the summer precipitation (indicator of summer monsoon intensity) decreased. Assuming a simple model that the monsoon is driven by the land-ocean temperature gradient, the cooling effect would be larger over the land than the sea.

  15. Effects of the Cessation of Mass Screening for Neuroblastoma at 6 Months of Age: A Population-Based Study in Osaka, Japan.

    PubMed

    Ioka, Akiko; Inoue, Masami; Yoneda, Akihiro; Nakamura, Tetsuro; Hara, Junichi; Hashii, Yoshiko; Sakata, Naoki; Yamato, Kazumi; Tsukuma, Hideaki; Kawa, Keisei

    2016-01-01

    In 2004, the Japanese government halted the 6-month mass screening program for neuroblastoma. We investigated whether its cessation had led to an increase not only in mortality due to this disease but also in the incidence of advanced-stage disease among older children. Study subjects were neuroblastoma patients retrieved from the population-based Osaka Cancer Registry. Trends of incidence and mortality from neuroblastoma were analyzed by calendar year and birth cohort. Prognostic factors, including stage and v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog (MYCN) oncogene status, were compared before and after the cessation of mass screening. Age-standardized incidence rates in 2005-2009 (the cessation period of mass screening; 11.1 per million) were similar to those in 1975-1979 (the pre-screening period; 8.6 per million). Age-standardized mortality rates tended to decrease from 1975-1979 (4.0 per million) to 2005-2009 (2.7 per million) in parallel with the improvement in survival. Analysis by birth cohort indicated that the mortality rates in 2004-2005 (after cessation) for children 0-4 years of age were lower than those in 1975-1979 (O:E ratio 0.25; 95% confidence interval, 0.03-0.90). For children 1-9 years of age, there was a not significant difference in the distribution of stage, MYCN oncogene status, and DNA ploidy between 1991-2003 (the mass screening period) and 2004-2008 (after cessation). The cessation of mass screening for neuroblastoma does not appear to have increased mortality due to this disease or incidence of advanced-stage disease among older children.

  16. Observed and simulated sensitivities of summertime urban surface air temperatures to anthropogenic heat in downtown areas of two Japanese Major Cities, Tokyo and Osaka

    NASA Astrophysics Data System (ADS)

    Kikegawa, Yukihiro; Tanaka, Ai; Ohashi, Yukitaka; Ihara, Tomohiko; Shigeta, Yoshinori

    2014-07-01

    In this study, the sensitivities of surface air temperatures to anthropogenic heat (AH) were investigated in downtowns of the two Japanese major cities, Tokyo and Osaka. First, meteorological measurements were made with the simultaneous monitoring of electricity demand in a contrastive couple of a downtown commercial area (C-area) and a residential area (R-area) within each city in summer 2007. From the measurements, the areal-mean surface air temperatures were obtained as and for each of the C-area and R-area, respectively. Using the actual electricity demand and the estimated motor fuels consumption, their areal total was evaluated as the energy-consumption-basis AH. The estimated C-areas' AH indicated greater values up to 220 W/m2 on weekdays and remarkable decrease about by half on weekends, whereas that in the R-areas showed less values of 10-20 W/m2 stably. Then, on calm and fine days were found to be systematically decreased from weekdays to weekends in both cities roughly indicating a proportional relationship with the reductions in the C-areas' AH on weekends. The result suggested a common afternoon sensitivity for both C-areas of around 1.0°C/100 W/m2, which indicated an intensity of the AH impact on surface air temperature there. Next, to simulate the observed AH impact, the authors' CM-BEM (a multilayer urban canopy model coupled with a building energy model) was newly implemented in the mesoscale Weather Research and Forecasting (WMF) model. This new system, WRF-CM-BEM, was applied to Tokyo and almost reasonably validated from the aspects of the reproducibility of urban surface air temperature and electricity demand in the observation areas. The simulations also suggested that WRF-CM-BEM underestimated the observed air temperature sensitivity to AH in the Tokyo C-area roughly by half but still in the same order of magnitude.

  17. Effects of the Cessation of Mass Screening for Neuroblastoma at 6 Months of Age: A Population-Based Study in Osaka, Japan

    PubMed Central

    Ioka, Akiko; Inoue, Masami; Yoneda, Akihiro; Nakamura, Tetsuro; Hara, Junichi; Hashii, Yoshiko; Sakata, Naoki; Yamato, Kazumi; Tsukuma, Hideaki; Kawa, Keisei

    2016-01-01

    Background In 2004, the Japanese government halted the 6-month mass screening program for neuroblastoma. We investigated whether its cessation had led to an increase not only in mortality due to this disease but also in the incidence of advanced-stage disease among older children. Methods Study subjects were neuroblastoma patients retrieved from the population-based Osaka Cancer Registry. Trends of incidence and mortality from neuroblastoma were analyzed by calendar year and birth cohort. Prognostic factors, including stage and v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog (MYCN) oncogene status, were compared before and after the cessation of mass screening. Results Age-standardized incidence rates in 2005–2009 (the cessation period of mass screening; 11.1 per million) were similar to those in 1975–1979 (the pre-screening period; 8.6 per million). Age-standardized mortality rates tended to decrease from 1975–1979 (4.0 per million) to 2005–2009 (2.7 per million) in parallel with the improvement in survival. Analysis by birth cohort indicated that the mortality rates in 2004–2005 (after cessation) for children 0–4 years of age were lower than those in 1975–1979 (O:E ratio 0.25; 95% confidence interval, 0.03–0.90). For children 1–9 years of age, there was a not significant difference in the distribution of stage, MYCN oncogene status, and DNA ploidy between 1991–2003 (the mass screening period) and 2004–2008 (after cessation). Conclusions The cessation of mass screening for neuroblastoma does not appear to have increased mortality due to this disease or incidence of advanced-stage disease among older children. PMID:26548355

  18. Trends in survival among elderly patients with out-of-hospital cardiac arrest: a prospective, population-based observation from 1999 to 2011 in Osaka.

    PubMed

    Kitamura, Tetsuhisa; Morita, Sachiko; Kiyohara, Kosuke; Nishiyama, Chika; Kajino, Kentaro; Sakai, Tomohiko; Nishiuchi, Tatsuya; Hayashi, Yasuyuki; Shimazu, Takeshi; Iwami, Taku

    2014-11-01

    Little is known about the improvement in out-of-hospital cardiac arrest (OHCA) survival among elderly patients. The aim of this study was to evaluate the trends in the survival after bystander-witnessed OHCA of cardiac origin in this age group. This prospective, population-based, observation of the whole population of Osaka, Japan included consecutive OHCA patients aged ≥65 years with emergency responder resuscitation attempts from January 1999 to December 2011. The primary outcome measure was one-month survival with neurologically favorable outcome, and the trends in the outcome from OHCA were evaluated by location. Multiple logistic regression analysis was used to assess factors that were potentially associated with neurologically favorable outcome. During the study period, a total of 10,876 bystander-witnessed OHCA of cardiac origin were eligible for our analyses. In whole arrests, the proportion of one-month survival with neurologically favorable outcome improved from 1.4% in 1999 to 4.8% in 2011 (P for trend <0.001). The proportion of neurologically favorable outcome in homes and public places improved from 0.7% in 1999 to 3.2% in 2011 (P for trend <0.001) and from 4.2% in 1999 to 20.9% in 2011 (P for trend <0.001), respectively, whereas, in nursing homes, the proportion of neurologically favorable outcome did not improve. In a multivariate analysis, bystander-initiated cardiopulmonary resuscitation and emergency response time were significant predictors for neurologically favorable outcome. In this population, survival from OHCA among elderly patients significantly improved during the study period, but the trends differed by the OHCA location. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  19. Factors associated with the difficulty in hospital acceptance among elderly emergency patients: A population-based study in Osaka City, Japan.

    PubMed

    Matsuyama, Tasuku; Kitamura, Tetsuhisa; Katayama, Yusuke; Kiyohara, Kosuke; Hayashida, Sumito; Kawamura, Takashi; Iwami, Taku; Ohta, Bon

    2017-06-18

    We aimed to investigate prehospital factors associated with difficulty in hospital acceptance among elderly emergency patients. We reviewed ambulance records in Osaka City from January 2013 through December 2014, and enrolled all elderly emergency patients aged ≥65 years who were transported by on-scene emergency medical service personnel to a hospital that the personnel had selected. The definition of difficulty in hospital acceptance was to the requirement for ≥4 phone calls to hospitals by emergency medical service personnel before receiving a decision from the destination hospitals. Prehospital factors associated with difficulty in hospital acceptance were examined through logistic regression analysis. During the study period, 72 105 elderly patients were included, and 13 332 patients (18.5%) experienced difficulty in hospital acceptance. In the simple linear regression model, hospital selection time increased significantly with an increasing number of phone calls (R(2)  = 0.774). In the multivariable analysis, older age (P for trend <0.001), calls from a healthcare facility (adjusted odds ratio [AOR] 1.23, 95% confidence interval [CI] 1.15-1.32), night-time (AOR 2.17, 95% CI 2.08-2.26) and weekend/holidays (AOR 1.43, 95% CI 1.38-1.49) were significantly associated with difficulty in hospital acceptance. A positive association was observed between gastrointestinal emergency-related symptoms and difficulty in hospital acceptance among elderly patients with symptoms of internal disease (AOR 1.71, 95% CI 1.53-1.91). In Japan, which has a rapidly aging population, a comprehensive strategy for elderly emergency patients, especially for advanced age groups or nursing home residents, is required. Geriatr Gerontol Int 2017; ••: ••-••. © 2017 Japan Geriatrics Society.

  20. Rationale, design, and profile of Comprehensive Registry of In-Hospital Intensive Care for OHCA Survival (CRITICAL) study in Osaka, Japan.

    PubMed

    Yamada, Tomoki; Kitamura, Tetsuhisa; Hayakawa, Koichi; Yoshiya, Kazuhisa; Irisawa, Taro; Abe, Yoshio; Ishiro, Megumi; Uejima, Toshifumi; Ohishi, Yasuo; Kaneda, Kazuhisa; Kiguchi, Takeyuki; Kishi, Masashi; Kishimoto, Masafumi; Nakao, Shota; Nishimura, Tetsuro; Hayashi, Yasuyuki; Morooka, Takaya; Izawa, Junichi; Shimamoto, Tomonari; Hatakeyama, Toshihiro; Matsuyama, Tasuku; Kawamura, Takashi; Shimazu, Takeshi; Iwami, Taku

    2016-01-01

    We established a multi-center, prospective cohort that could provide appropriate therapeutic strategies such as criteria for the introduction and the effectiveness of in-hospital advanced treatments, including percutaneous coronary intervention (PCI), target temperature management, and extracorporeal cardiopulmonary resuscitation (ECPR) for out-of-hospital cardiac arrest (OHCA) patients. In Osaka Prefecture, Japan, we registered all consecutive patients who were suffering from an OHCA for whom resuscitation was attempted and who were then transported to institutions participating in this registry since July 1, 2012. A total of 11 critical care medical centers and one hospital with an emergency care department participated in this registry. The primary outcome was neurological status after OHCA, defined as cerebral performance category (CPC) scale. A total of 688 OHCA patients were documented between July 2012 and December 2012. Of them, 657 were eligible for our analysis. Patients' average age was 66.2 years old, and male patients accounted for 66.2 %. The proportion of OHCAs having a cardiac origin was 50.4 %. The proportion as first documented rhythm of ventricular fibrillation/pulseless ventricular tachycardia was 11.6 %, pulseless electrical activity 23.4 %, and asystole 54.5 %. After hospital arrival, 10.5 % received defibrillation, 90.8 % tracheal intubation, 3.0 % ECPR, 3.5 % PCI, and 83.1 % adrenaline administration. The proportions of 90-day survival and CPC 1/2 at 90 days after OHCAs were 5.9 and 3.0 %, respectively. The Comprehensive Registry of In-hospital Intensive Care for OHCA Survival (CRITICAL) study will enroll over 2000 OHCA patients every year. It is still ongoing without a set termination date in order to provide valuable information regarding appropriate therapeutic strategies for OHCA patients (UMIN000007528).

  1. Relationship between preventive health services and use of inpatient and outpatient care by residents aged 40 or older in 44 municipalities in Osaka Prefecture, Japan.

    PubMed

    Nakanishi, N; Tatara, K

    1998-12-01

    We examined the relationships between preventive health services provided under the Law for Health and Medical Services for the Elderly and the use of inpatient and outpatient care by insured residents aged 40 or older covered by the National Health Insurance in 44 municipalities in Osaka Prefecture. Factor analyses showed that hospital admission rate and inpatient days per 100 insured persons, bed days per insured person, inpatient days per case, mean bed days, the proportion of long-stay (180 days or more), and the rate of long-stay per 1,000 insured persons accounted for the first factors of inpatient care with factor loadings of more than 0.82. Outpatient utilization rate and outpatient days per 100 insured persons comprised the first factors of outpatient care with factor loadings of more than 0.80. Patient cost per case and the proportion of high patient cost (600,000 Yen or more for inpatient care and 60,000 Yen or more for outpatient care) made up the second factors of either type of patient care with factor loadings of more than 0.87. The frequency of use of health check-ups and the numbers of instruction classes and participants in health education and health counseling per 100 residents showed negative correlations with indices of inpatient and outpatient care, except for patient cost per day. The scores for the first and second factors of inpatient care and for the first factor of outpatient care correlated negatively with all indices of the use of preventive health services. More active provision of preventive health services may therefore contribute to reducing the subsequent use of inpatient and outpatient care among residents aged 40 or older.

  2. The Fourth International Network of Twin Registries: Overview from Osaka/Research Reviews: Familial Fraternal Twinning; Twin Study of Masculine Faces; Physical Aggression and Epigenetics; Prenatal Education for Parents of Twins/Current Events: 2016 Guinness Book of World Records; Oldest Living Male Twins; Twins Reunited at Sixty-Nine; Panda Twins; Twins.com.

    PubMed

    Segal, Nancy L

    2015-12-01

    The 4th International Network of Twin Registries (INTR) Consortium Meeting took place in Osaka, Japan, September 28-29, 2015. The venue was the Osaka Medical Center for Medical Innovation and Translational Research. An overview of presentations and other activities is provided. Next, 1930s research on familial fraternal twinning, preference for masculine faces, physical aggression and epigenetics, and a prenatal education program for parents of multiples are described. Current twin-related events include the 2016 Guinness Book of World Records (GWR), the oldest living male twins, newly reunited twins, the birth of panda twins and a controversial twin-based website.

  3. Residential proximity to main roads during pregnancy and the risk of allergic disorders in Japanese infants: the Osaka Maternal and Child Health Study.

    PubMed

    Miyake, Yoshihiro; Tanaka, Keiko; Fujiwara, Hiroshi; Mitani, Yasuhiro; Ikemi, Hiroaki; Sasaki, Satoshi; Ohya, Yukihiro; Hirota, Yoshio

    2010-02-01

    The role of traffic-related air pollution in the initiation of allergic disorders in children is still not clearly understood. The present prospective study examined the relation between proximity of the home during pregnancy to the nearest main road, which was used as a surrogate for traffic-related air pollutants, and the risk of allergic disorders in Japanese infants in an urban area. Subjects were 756 mother-child pairs. Distance of each subject's home during pregnancy from the center line of all of the 235 main roads in Osaka Prefecture was computed using geographical information system software. The first survey during pregnancy and the second survey between 2 and 9 months post-partum collected information on potential confounding factors. In the third survey, which was from 16 to 24 months post-partum, a self-administered questionnaire included questions on allergic disorders. In the third survey, 22.1% and 18.7% of infants became positive for wheeze and atopic eczema based on criteria of the International Study of Asthma and Allergies in Childhood (ISAAC), respectively. The risk of doctor-diagnosed asthma and doctor-diagnosed atopic eczema was 4.4% and 8.9%, respectively. A shorter distance of the residence during pregnancy from the nearest main road was associated with an increased risk of doctor-diagnosed asthma and atopic eczema (adjusted odds ratios for comparison of <50 m with 200 m or more = 4.01 and 2.26, 95% confidence intervals: 1.44-11.24 and 1.08-4.59, p for trend = 0.02 and 0.03, respectively). No evident relationships were observed between the distance of the residence during pregnancy from the nearest main road and the risk of wheeze or atopic eczema based on the ISAAC criteria. It was difficult to distinguish the effect of the pre-natal from the post-natal exposure because most subjects lived at the same home address both before and after childbirth. Our results are likely to support the hypothesis that intrauterine exposure to traffic

  4. Efficacy of the Osaka Medical College (OMC) brace in the treatment of adolescent idiopathic scoliosis following Scoliosis Research Society brace studies criteria.

    PubMed

    Kuroki, Hiroshi; Inomata, Naoki; Hamanaka, Hideaki; Higa, Kiyoshi; Chosa, Etsuo; Tajima, Naoya

    2015-01-01

    The efficacy of brace treatment for patients with adolescent idiopathic scoliosis (AIS) remains controversial. To make comparisons among studies more valid and reliable, the Scoliosis Research Society (SRS) has standardized criteria for brace studies in patients with AIS. The purpose of this study was to evaluate the efficacy of the Osaka Medical College (OMC) brace for AIS in accordance with the modified standardized criteria proposed by the SRS committee on bracing and non-operative management. From 1999 through 2010, 31 consecutive patients with AIS who were newly prescribed the OMC brace and met the modified SRS criteria were studied. The study included 2 boys and 29 girls with a mean age of 12 years and 0 month. Patients were instructed to wear the brace for a minimum of 20 hours per day at the beginning of brace treatment. The mean duration of brace treatment was 4 years and 8 months. We examined the initial brace correction rate and the clinical outcomes of main curves evaluated by curve progression and surgical rate, and the compliance evaluated by the instruction adherence rate for all cases. The clinical course of the brace treatment was considered progression if ≥6° curvature increase occurred and improvement if ≥6° curvature decrease occurred according to SRS judgment criteria. The average initial brace correction rate was 46.8%. In 10 cases the curve progressed, 6 cases the curve improved, and 15 cases the curve remained unchanged (success rate: 67.7%). The mean instruction adherence rate, that was defined the percentage of the visits that patients declared they mostly followed our instruction to total visits, was 53.7%. The success rate was statistically higher in the patient group whose instruction adherence rate was greater than 50% (88.2%) as compared with in those 50% or less (42.8%). OMC brace treatment for AIS patients could alter the natural history and significantly decreased the progression of curves to the threshold for surgical

  5. Clinical use of molecular targeted agents for primary small bowel adenocarcinoma: A multicenter retrospective cohort study by the Osaka Gut Forum.

    PubMed

    Hirao, Motohiro; Komori, Masato; Nishida, Tsutomu; Iijima, Hideki; Yamaguchi, Shinjiro; Ishihara, Ryu; Yasunaga, Yuichi; Kobayashi, Ichizo; Kishida, Osamu; Oshita, Masahide; Hagiwara, Hideki; Ito, Toshifumi; Suzuki, Kunio; Hayashi, Yoshito; Inoue, Takahiro; Tsujii, Masahiko; Yoshihara, Harumasa; Takehara, Tetsuo

    2017-08-01

    Primary small bowel adenocarcinoma (SBA) is a rare cancer for which effective treatment strategies have not yet been established. The results of previous retrospective studies suggest that chemotherapy contributes to a longer survival time in patients with SBA. However, there are few case reports about the efficacy of molecular targeted agent-containing chemotherapy for SBA. In the present study, the treatment and follow-up data of patients with SBA who received chemotherapy with or without molecular targeted agents were retrospectively analyzed. Each patient was treated in one of ten hospitals participating in the Osaka Gut Forum between April 2006 and March 2014. The following factors were evaluated: Age, sex, Eastern Cooperative Oncology Group performance status (PS), tumor location, tumor differentiation, chemotherapy regimen, resection of primary tumor, tumor biomarker expression, distant metastasis, best response under chemotherapy, time to disease progression, subsequent treatments, survival status and treatment toxicity. A total of 27 patients (17 males and 10 females; mean age, 63.4 years old; range, 36-83 years old) received chemotherapy due to non-curative tumor resection, unresectable tumor or post-operative recurrence. The median overall survival time was 14.8 months (range, 2-58 months). A univariate analysis revealed a PS of 0 (P=0.0228) and treatment with platinum-based chemotherapy (P=0.0048) were significant factors for an improved prognosis. An age-adjusted multivariate analysis also revealed that a platinum-based regimen was a significant positive prognostic factor (P=0.0373). Molecular targeted agents were administered to 8 patients, for whom it was their first- or second-line therapy. Among the 17 patients who received oxaliplatin-based chemotherapy as a first-line chemotherapy, a PS of 0 (P=0.0255) and treatment with bevacizumab (P=0.0121) were significant positive prognostic factors. Toxicities higher than Grade 3 occurred in 8/27 patients

  6. Familial Alzheimer's disease Osaka mutant (ΔE22) β-barrels suggest an explanation for the different Aβ1-40/42 preferred conformational states observed by experiment.

    PubMed

    Jang, Hyunbum; Arce, Fernando Teran; Ramachandran, Srinivasan; Kagan, Bruce L; Lal, Ratnesh; Nussinov, Ruth

    2013-10-03

    An unusual ΔE693 mutation in the amyloid precursor protein (APP) producing a β-amyloid (Aβ) peptide lacking glutamic acid at position 22 (Glu22) was recently discovered, and dabbed the Osaka mutant (ΔE22). Previously, several point mutations in the Aβ peptide involving Glu22 substitutions were identified and implicated in the early onset of familial Alzheimer's disease (FAD). Despite the absence of Glu22, the Osaka mutant is also associated with FAD, showing a recessive inheritance in families affected by the disease. To see whether this aggregation-prone Aβ mutant could directly relate to the Aβ ion channel-mediated mechanism as observed for the wild type (WT) Aβ peptide in AD pathology, we modeled Osaka mutant β-barrels in a lipid bilayer. Using molecular dynamics (MD) simulations, two conformer ΔE22 barrels with the U-shaped monomer conformation derived from NMR-based WT Aβ fibrils were simulated in explicit lipid environment. Here, we show that the ΔE22 barrels obtain the lipid-relaxed β-sheet channel topology, indistinguishable from the WT Aβ1-42 barrels, as do the outer and pore dimensions of octadecameric (18-mer) ΔE22 barrels. Although the ΔE22 barrels lose the cationic binding site in the pore which is normally provided by the negatively charged Glu22 side chains, the mutant pores gain a new cationic binding site by Glu11 at the lower bilayer leaflet, and exhibit ion fluctuations similar to the WT barrels. Of particular interest, this deletion mutant suggests that toxic WT Aβ1-42 would preferentially adopt a less C-terminal turn similar to that observed for Aβ17-42, and explains why the solid state NMR data for Aβ1-40 point to a more C-terminal turn conformation. The observed ΔE22 barrels conformational preferences also suggest an explanation for the lower neurotoxicity in rat primary neurons as compared to WT Aβ1-42.

  7. Shielding experiments of concrete and iron for the 244 MeV and 387 MeV quasi-mono energetic neutrons using an organic scintillator (at RCNP, Osaka Univ.)

    NASA Astrophysics Data System (ADS)

    Hagiwara, Masayuki; Iwase, Hiroshi; Iwamoto, Yosuke; Satoh, Daiki; Matsumoto, Tetsuro; Masuda, Akihiko; Yashima, Hiroshi; Nakane, Yoshihiro; Nakashima, Hiroshi; Sakamoto, Yukio; Shima, Tatsushi; Tamii, Atsushi; Hatanaka, Kichiji; Nakamura, Takashi

    2017-09-01

    A shielding benchmark experiment has been performed using a quasi-monoenergetic 7Li(p,n) neutron source with the peak energies of 244 and 387 MeV at the Research Center for Nuclear Physics (RCNP) of Osaka University, in order to assess the accuracy of nuclear data and calculation codes used in high-energy accelerator shielging design. Energy spectra behind bulk shields of 10- to 100-cm-thick iron, 25- to 300-cm-thick concrete and their composite are measured using a NE213 organic liquid scintillator with a diameter and thickness of 25.4 cm each with a time-of-flight and an unfolding method. The neutron attenuation lengths are illustared for iron and concrete as a function of the incident energy.

  8. A Phase I/II trial of radiotherapy concurrent with TS-1 plus cisplatin in patients with clinically resectable type 4 or large type 3 gastric cancer: Osaka Gastrointestinal Cancer Chemotherapy Study Group OGSG1205.

    PubMed

    Imano, Motohiro; Furukawa, Hiroshi; Yokokawa, Masaki; Nishimura, Yasumasa; Kurokawa, Yukinori; Satoh, Taroh; Sakai, Daisuke; Yasuda, Takushi; Imamoto, Haruhiko; Tujinaka, Toshimasa; Shimokawa, Toshio; Shiozaki, Hitoshi

    2013-04-01

    A Phase I/II trial of radiotherapy administered concurrently with TS-1 plus cisplatin has been initiated in Japanese patients with clinical resectable type 4 or large type 3 gastric cancer. The aim of this trial is to determine the recommended dose of TS-1 and cisplatin combined with radiotherapy at a fixed dose in the Phase I study, and to evaluate the efficacy and safety in the Phase II study. The primary endpoint for Phase II is the pathological complete response rate, assessed using surgically resected specimens. Secondary endpoints are the response rate, progression-free survival, overall survival, operation transitional rate, R0 resection rate, rate of treatment completion, rate of down-staging and rates of postoperative complications and adverse events. In Phase II, a total of 30 patients will be enrolled in the Osaka Gastrointestinal Cancer Chemotherapy Study Group trial over a period of 6 years.

  9. Antimicrobial Resistance and Molecular Typing of Neisseria gonorrhoeae Isolates in Kyoto and Osaka, Japan, 2010 to 2012: Intensified Surveillance after Identification of the First Strain (H041) with High-Level Ceftriaxone Resistance

    PubMed Central

    Shimuta, Ken; Unemo, Magnus; Nakayama, Shu-ichi; Morita-Ishihara, Tomoko; Dorin, Misato; Kawahata, Takuya

    2013-01-01

    In 2009, the first high-level ceftriaxone-resistant Neisseria gonorrhoeae strain (H041) was isolated in Kyoto, Japan. The present study describes an intensified surveillance (antimicrobial resistance and molecular typing) of Neisseria gonorrhoeae isolates in Kyoto and its neighboring prefecture Osaka, Japan, in 2010 to 2012, which was initiated after the identification of H041. From April 2010 to March 2012, 193 N. gonorrhoeae isolates were collected and the MICs (μg/ml) to six antimicrobials, including ceftriaxone, were determined. All isolates showed susceptibility to ceftriaxone and cefixime (MIC values, <0.5 μg/ml), and spectinomycin. The rates of resistance (intermediate susceptibility) to azithromycin, penicillin G, and ciprofloxacin were 3.6% (19.7%), 24.4% (71.0%), and 78.2% (0.5%), respectively. Multilocus sequence typing (MLST) showed that 40.9%, 19.2%, and 17.1% of isolates belonged to ST1901, ST7359, and ST7363, respectively. Furthermore, N. gonorrhoeae multiantigen sequence typing (NG-MAST) revealed that 12 (63%) of the 19 isolates with decreased susceptibility to ceftriaxone (MIC > 0.064 μg/ml) were of ST1407. NG-MAST ST1407 was also the most prevalent ST (16.1%; 31 of 193 isolates). In those NG-MAST ST1407 strains, several mosaic type penA alleles were found, including SF-A type (penicillin binding protein 2 allele XXXIV) and its derivatives. These were confirmed using transformation of the penA mosaic alleles as critical determinants for enhanced cefixime and ceftriaxone MICs. The intensified surveillance in Kyoto and Osaka, Japan, did not identify any dissemination of the high-level ceftriaxone-resistant N. gonorrhoeae strain H041, suggesting that H041 might have caused only a sporadic case and has not spread further. PMID:23939890

  10. EDITORIAL: Artificial Muscles: Selected papers from the 5th World Congress on Biomimetics, Artificial Muscles and Nano-Bio (Osaka, Japan, 25-27 November 2009) Artificial Muscles: Selected papers from the 5th World Congress on Biomimetics, Artificial Muscles and Nano-Bio (Osaka, Japan, 25-27 November 2009)

    NASA Astrophysics Data System (ADS)

    Shahinpoor, Mohsen

    2011-12-01

    The 5th World Congress on Biomimetics, Artificial Muscles and Nano-Bio and the 4th International Conference on Artificial Muscles were held in Osaka, Japan, 23-27 November 2009. This special section of Smart Materials and Structures is devoted to a selected number of research papers presented at this international conference and congress. Of the 76 or so papers presented at the conference, only 10 papers were finally selected, reviewed and accepted for this special section, following the regular reviewing procedures of the journal. This special section is focused on polymeric artificial muscles, electroactive polymers, multifunctional nanocomposites and their applications. In particular, an electromechanical model for self-sensing ionic polymer-metal composite actuating devices with patterned surface electrodes is presented which discusses the concept of creating self-sensing ionic polymer-metal composite (IPMC) actuating devices with patterned surface electrodes where actuator and sensor elements are separated by a grounded shielding electrode. Eventually, an electromechanical model of the device is also proposed and validated. Following that, there is broad coverage of polytetrahydrofurane-polyethylene oxide-PEDOT conducting interpenetrating polymer networks (IPNs) for high speed actuators. The conducting polymer (poly(3,4-ethylenedioxythiophene)) is incorporated within the IPNs, which are synthesized from polyethylene oxide (PEO)/polytetrahydrofurane (PTHF) networks. PEO/PTHF IPNs are prepared using poly(ethylene glycol) methacrylate and dimethacrylate and hydroxythelechelic PTHF as starting materials. The conducting IPN actuators are prepared by oxidative polymerization of 3,4-ethylenedioxithiophene (EDOT) using FeCl3 as an oxidizing agent within the PEO/PTHF IPN host matrix. Subsequently, giant and reversible magnetorheology of carrageenan/iron oxide magnetic gels are discussed and the effect of magnetic fields on the viscoelastic properties

  11. Improvements in Patient Acceptance by Hospitals Following the Introduction of a Smartphone App for the Emergency Medical Service System: A Population-Based Before-and-After Observational Study in Osaka City, Japan

    PubMed Central

    Katayama, Yusuke; Kiyohara, Kosuke; Iwami, Taku; Kawamura, Takashi; Izawa, Junichi; Gibo, Koichiro; Komukai, Sho; Hayashida, Sumito; Kiguchi, Takeyuki; Ohnishi, Mitsuo; Ogura, Hiroshi

    2017-01-01

    Background Recently, the number of ambulance dispatches has been increasing in Japan, and it is therefore difficult for hospitals to accept emergency patients smoothly and appropriately because of the limited hospital capacity. To facilitate the process of requesting patient transport and hospital acceptance, an emergency information system using information technology (IT) has been built and introduced in various communities. However, its effectiveness has not been thoroughly revealed. We introduced a smartphone app system in 2013 that enables emergency medical service (EMS) personnel to share information among themselves regarding on-scene ambulances and the hospital situation. Objective The aim of this study was to assess the effects of introducing this smartphone app on the EMS system in Osaka City, Japan. Methods This retrospective study analyzed the population-based ambulance records of Osaka Municipal Fire Department. The study period was 6 years, from January 1, 2010 to December 31, 2015. We enrolled emergency patients for whom on-scene EMS personnel conducted hospital selection. The main endpoint was the difficulty experienced in gaining hospital acceptance at the scene. The definition of difficulty was making ≥5 phone calls by EMS personnel at the scene to hospitals until a decision to transport was determined. The smartphone app was introduced in January 2013, and we compared the patients treated from 2010 to 2012 (control group) with those treated from 2013 to 2015 (smartphone app group) using an interrupted time-series analysis to assess the effects of introducing this smartphone app. Results A total of 600,526 emergency patients for whom EMS personnel selected hospitals were eligible for our analysis. There were 300,131 emergency patients in the control group (50.00%, 300,313/600,526) from 2010 to 2012 and 300,395 emergency patients in the smartphone app group (50.00%, 300,395/600,526) from 2013 to 2015. The rate of difficulty in hospital acceptance

  12. Improvements in Patient Acceptance by Hospitals Following the Introduction of a Smartphone App for the Emergency Medical Service System: A Population-Based Before-and-After Observational Study in Osaka City, Japan.

    PubMed

    Katayama, Yusuke; Kitamura, Tetsuhisa; Kiyohara, Kosuke; Iwami, Taku; Kawamura, Takashi; Izawa, Junichi; Gibo, Koichiro; Komukai, Sho; Hayashida, Sumito; Kiguchi, Takeyuki; Ohnishi, Mitsuo; Ogura, Hiroshi; Shimazu, Takeshi

    2017-09-11

    Recently, the number of ambulance dispatches has been increasing in Japan, and it is therefore difficult for hospitals to accept emergency patients smoothly and appropriately because of the limited hospital capacity. To facilitate the process of requesting patient transport and hospital acceptance, an emergency information system using information technology (IT) has been built and introduced in various communities. However, its effectiveness has not been thoroughly revealed. We introduced a smartphone app system in 2013 that enables emergency medical service (EMS) personnel to share information among themselves regarding on-scene ambulances and the hospital situation. The aim of this study was to assess the effects of introducing this smartphone app on the EMS system in Osaka City, Japan. This retrospective study analyzed the population-based ambulance records of Osaka Municipal Fire Department. The study period was 6 years, from January 1, 2010 to December 31, 2015. We enrolled emergency patients for whom on-scene EMS personnel conducted hospital selection. The main endpoint was the difficulty experienced in gaining hospital acceptance at the scene. The definition of difficulty was making ≥5 phone calls by EMS personnel at the scene to hospitals until a decision to transport was determined. The smartphone app was introduced in January 2013, and we compared the patients treated from 2010 to 2012 (control group) with those treated from 2013 to 2015 (smartphone app group) using an interrupted time-series analysis to assess the effects of introducing this smartphone app. A total of 600,526 emergency patients for whom EMS personnel selected hospitals were eligible for our analysis. There were 300,131 emergency patients in the control group (50.00%, 300,313/600,526) from 2010 to 2012 and 300,395 emergency patients in the smartphone app group (50.00%, 300,395/600,526) from 2013 to 2015. The rate of difficulty in hospital acceptance was 14.19% (42,585/300,131) in the

  13. Analysis of late toxicity associated with external beam radiation therapy for prostate cancer with uniform setting of classical 4-field 70 Gy in 35 fractions: a survey study by the Osaka Urological Tumor Radiotherapy Study Group

    PubMed Central

    Yoshioka, Yasuo; Suzuki, Osamu; Nishimura, Kazuo; Inoue, Hitoshi; Hara, Tsuneo; Yoshida, Ken; Imai, Atsushi; Tsujimura, Akira; Nonomura, Norio; Ogawa, Kazuhiko

    2013-01-01

    We aimed to analyse late toxicity associated with external beam radiation therapy (EBRT) for prostate cancer using uniform dose-fractionation and beam arrangement, with the focus on the effect of 3D (CT) simulation and portal field size. We collected data concerning patients with localized prostate adenocarcinoma who had been treated with EBRT at five institutions in Osaka, Japan, between 1998 and 2006. All had been treated with 70 Gy in 35 fractions, using the classical 4-field technique with gantry angles of 0°, 90°, 180° and 270°. Late toxicity was evaluated strictly in terms of the Common Terminology Criteria for Adverse Events Version 4.0. In total, 362 patients were analysed, with a median follow-up of 4.5 years (range 1.0–11.6). The 5-year overall and cause-specific survival rates were 93% and 96%, respectively. The mean ± SD portal field size in the right–left, superior–inferior, and anterior–posterior directions was, respectively, 10.8 ± 1.1, 10.2 ± 1.0 and 8.8 ± 0.9 cm for 2D simulation, and 8.4 ± 1.2, 8.2 ± 1.0 and 7.7 ± 1.0 cm for 3D simulation (P < 0.001). No Grade 4 or 5 late toxicity was observed. The actuarial 5-year Grade 2–3 genitourinary and gastrointestinal (GI) late toxicity rates were 6% and 14%, respectively, while the corresponding late rectal bleeding rate was 23% for 2D simulation and 7% for 3D simulation (P < 0.001). With a uniform setting of classical 4-field 70 Gy/35 fractions, the use of CT simulation and the resultant reduction in portal field size were significantly associated with reduced late GI toxicity, especially with less rectal bleeding. PMID:22988284

  14. A survey of dietary intake of polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans, and dioxin-like coplanar polychlorinated biphenyls from food during 2000-2002 in Osaka City, Japan.

    PubMed

    Nakatani, Tadashi; Yamamoto, Atsushi; Ogaki, Sumiko

    2011-04-01

    Studies of the dietary intake of polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and dioxin-like coplanar polychlorinated biphenyls (dioxin-like PCBs), collectively referred as dioxins, were conducted using the total diet study (TDS) method with food purchased in Osaka City, Japan during 2000-2002. The daily intake of dioxin-TEQ (toxic equivalent) from food per adult person was estimated respectively as 104.24 pg TEQ/person/day in 2000, 72.73 pg TEQ/person/day in 2001, and 87.28 pg TEQ/person/day in 2002, corresponding to 2.08, 1.45, and 1.74 pg TEQ/kg body weight (bw)/day for an adult weighing 50 kg. The highest contribution ratio to the total intake of dioxin-TEQ was from fish and shellfish (group 10) in each year, accounting for 77-92%. The next highest contributor was meat and eggs (groups 11-A and 11-B). An annual decrease of the intake of dioxin-TEQ was not observed clearly. Otherwise, the dietary intake of non-2,3,7,8-substituted PCDDs/PCDFs were estimated together. The intake of 1,3,6,8-TeCDD came mostly from intake of fish and shellfish (group 10), green vegetable (group 7), and the other vegetables, including mushrooms and seaweed (group 8). In addition, the intake of 1,3,6,8-TeCDF, which reportedly antagonizes 2,3,7,8-TeCDD-mediated aryl hydrocarbon hydroxylase (AHH) and ethoxyresorufin O-deethylase (EROD) induction activities, was an insufficient amount to suppress 2,3,7,8-TeCDD-mediated activities. Furthermore, we discussed different TEQ compositions of PCDDs/PCDFs to dioxin-like PCBs from food intake and in human samples and inferred that the difference was caused by low bioaccumulation properties of 3,3',4,4',5-PeCB (PCB 126). © Springer Science+Business Media, LLC 2010

  15. Individualized and institutionalized residential place-based discrimination and self-rated health: a cross-sectional study of the working-age general population in Osaka city, Japan

    PubMed Central

    2014-01-01

    Background Several studies have reported that individualized residential place-based discrimination (PBD) affects residents’ health. However, studies exploring the association between institutionalized PBD and health are scarce, especially in Asian countries including Japan. Methods A cross-sectional study was conducted with random two-stage sampling of 6191 adults aged 25–64 years in 100 census tracts across Osaka city in 2011. Of 3244 respondents (response rate 52.4%), 2963 were analyzed using multilevel logistic regression to examine the association of both individualized and institutionalized PBD with self-rated health (SRH) after adjustment for individual-level factors such as socioeconomic status (SES). An area-level PBD indicator was created by aggregating individual-level PBD responses in each tract, representing a proxy for institutionalized PBD, i.e., the concept that living in a stigmatized neighborhood affects neighborhood health. 100 tracts were divided into quartiles in order. The health impact of area-level PBD was compared with that of area-level SES indicators (quartile) such as deprivation. Results After adjustment for individual-level PBD, the highest and third area-level PBD quartiles showed odds ratio (OR) 1.57 (95% credible interval: 1.13-2.18) and 1.38 (0.99-1.92), respectively, for poor SRH compared with the lowest area-level PBD quartile. In a further SES-adjusted model, ORs of area-level PBD (highest and third quartile) were attenuated to 1.32 and 1.31, respectively, but remained marginally significant, although those of the highest area-level not-home-owner (census-based indicator) and deprivation index quartiles were attenuated to 1.26 and 1.21, respectively, and not significant. Individual-level PBD showed significant OR 1.89 (1.33-2.81) for poor SRH in an age, sex, PBD and SES-adjusted model. Conclusion Institutionalized PBD may be a more important environmental determinant of SRH than other area-level SES indicators such as

  16. [Neonatal cyanosis due to fetal hemoglobin M-Osaka].

    PubMed

    Charon, A; Henrion, E; Delpire, S; Redondi, A; Lecart, C

    2011-10-01

    The case of a newborn with isolated neonatal cyanosis on day 1 is reported. The basic investigations were sufficient to reach the diagnosis. A rare abnormal fetal hemoglobin was isolated. The prognosis of this disease is excellent and self-resolving. Copyright © 2011 Elsevier Masson SAS. All rights reserved.

  17. Style Shifting from "Hyojungo" to Osaka-ben.

    ERIC Educational Resources Information Center

    Hallmon, Jennifer

    A study examined the shift from standard spoken Japanese to dialect and compared it to the shift from formal to informal forms, within the context of several theories of code-switching and style-shifting. A five-minute segment was taken from a 30-minute conversation between three female native Japanese-speakers, all familiar with the Osaka…

  18. Effect of oral intake of choline-stabilized orthosilicic acid on skin, nails and hair in women with photodamaged skin.

    PubMed

    Barel, A; Calomme, M; Timchenko, A; De Paepe, K; Paepe, K De; Demeester, N; Rogiers, V; Clarys, P; Vanden Berghe, D

    2005-10-01

    Chronic exposure of the skin to sunlight causes damage to the underlying connective tissue with a loss of elasticity and firmness. Silicon (Si) was suggested to have an important function in the formation and maintenance of connective tissue. Choline-stabilized orthosilicic acid ("ch-OSA") is a bioavailable form of silicon which was found to increase the hydroxyproline concentration in the dermis of animals. The effect of ch-OSA on skin, nails and hair was investigated in a randomized, double blind, placebo-controlled study. Fifty women with photodamaged facial skin were administered orally during 20 weeks, 10 mg Si/day in the form of ch-OSA pellets (n=25) or a placebo (n=25). Noninvasive methods were used to evaluate skin microrelief (forearm), hydration (forearm) and mechanical anisotropy (forehead). Volunteers evaluated on a virtual analog scale (VAS, "none=0, severe=3") brittleness of hair and nails. The serum Si concentration was significantly higher after a 20-week supplementation in subjects with ch-OSA compared to the placebo group. Skin roughness parameters increased in the placebo group (Rt:+8%; Rm: +11%; Rz: +6%) but decreased in the ch-OSA group (Rt: -16%; Rm: -19%; Rz: -8%). The change in roughness from baseline was significantly different between ch-OSA and placebo groups for Rt and Rm. The difference in longitudinal and lateral shear propagation time increased after 20 weeks in the placebo group but decreased in the ch-OSA group suggesting improvement in isotropy of the skin. VAS scores for nail and hair brittleness were significantly lower after 20 weeks in the ch-OSA group compared to baseline scores. Oral intake of ch-OSA during the 20 weeks results in a significant positive effect on skin surface and skin mechanical properties, and on brittleness of hair and nails.

  19. Dark matter search with CaF2 scintillator at Osaka

    NASA Astrophysics Data System (ADS)

    Ogawa, I.; Hazama, R.; Mukaida, K.; Kishimoto, K.; Sakai, H.; Katsuki, A.; Itamura, T.; Umehara, S.; Yoshida, S.; Kishimoto, T.

    2008-07-01

    A CaF2 scintillator complex system (ELEGANT VI) is developed to search for the axial-vector coupled dark matter (WIMPs) and study the neutrino-less double beta decay of 48 Ca. Active light guides of pure CaF2 crystals which are on both sides of the central CaF2(Eu) crystal act as a 4π active shield, combined with surrounding CsI(T1) scintillators. The whole system is at the underground laboratory (Oto Cosmo Observatory) located in Nara. In this article our current status of the investigation are described, especially putting emphasis on the development of flash scaler to do a single photon counting.

  20. Dark Matter Search with CaF2 Scintillators in Osaka

    NASA Astrophysics Data System (ADS)

    Ogawa, I.; Kishimoto, T.; Hazama, R.; Ajimura, S.; Matsuoka, K.; Suzuki, N.; Nitta, T.; Miyawaki, H.; Shiomi, S.; Tanaka, Y.; Ejiri, H.; Kudomi, N.; Kume, K.; Ohsumi, H.; Fushimi, K.

    2000-01-01

    A detector system which consists of CaF2 scintillators surrounded by active and passive shields, is developed to search for spin coupled dark matter. The whole system is in operation at the underground laboratory located in Nara (Oto Cosmo Observatory) which has effectively 1.2 km water equivalent shield. In this article our current status of the investigation is described.

  1. Highlighting the history of Japanese radio astronomy. 5: The 1950 Osaka solar grating array proposal

    NASA Astrophysics Data System (ADS)

    Wendt, Harry; Orchiston, Wayne; Ishiguro, Masato; Nakamura, Tsuko

    2017-04-01

    In November 1950, a paper was presented at the 5th Annual Assembly of the Physical Society of Japan that outlined the plan for a radio frequency grating array, designed to provide high-resolution observations of solar radio emission at 3.3 GHz. This short paper provides details of the invention of this array, which occurred independently of W.N. Christiansen's invention of the solar grating array in Australia at almost the same time.

  2. Development of an electrohydraulic total artificial heart at the National Cardiovascular Center, Osaka, Japan.

    PubMed

    Masuzawa, T; Taenaka, Y; Tatsumi, E; Choi, W W; Toda, K; Ohno, T; Baba, Y; Nakatani, T; Takano, H; Uyama, C

    1995-01-01

    The authors have been developing an electrohydraulic total artificial heart with a basic concept placing the blood pumps and an electrohydraulic energy converter separately, in the thorax and the abdominal region, respectively, to minimize anatomic constraints. Major problems of the system were a high energy consumption of 56 W at 6 L/min output and an insufficient maximum output of 6.7 L/min. The energy converter was redesigned to overcome these problems. A three phase, 4 pole brushless DC motor, which has maximum efficiency of 79% at a motor rotation of 2500 rpm with a load of 0.1 Nm, was developed for the new energy converter. Flow-channel design of the regenerative oil pump was optimized, which resulted in increasing the maximum flow rate at one directional motor rotation from 18 to 29 L/min. In vitro performance of the electrohydraulic total artificial heart was evaluated in a mock circulation with physiologic pressure conditions. Maximum output was increased to 10.7 L/min at a pump rate of 120 bpm and energy consumption of the motor at 6 L/min output was reduced to 18 W. Based upon these favorable results, the system is now being assembled for chronic animal implantation.

  3. Dense plasma focus research at the Institute of Laser Engineering, Osaka (Japan)

    NASA Astrophysics Data System (ADS)

    Yokoyama, M.; Yamamoto, Y.; Kisoda, A.; Yamada, Y.; Kitagawa, Y.; Yamanaka, M.; Yamanaka, C.

    1983-09-01

    Research using a 50 kV/50 kJ deuterium plasma focus with 1.25 MA maximum current is summarized. Plasma dynamics in implosion phase of dense plasma focus were investigated by 2nsec ruby laser holographic interferometry and shadowgraphy. Radial pinch velocity of the plasma column and ionizing front velocity are 20 million cm/sec. Rayleigh-Taylor instability is observed in the early stage of the implosion phase. Effects of CO2 laser light on a dense plasma focus are discussed. High energy deuteron intensity, energy spectrum, and angular distribution were measured from radioactivity induced in graphite, aliminum and copper in ion dominant low pressure mode and neutron dominant high pressure mode.

  4. Clinical results with Jarvik 2000 axial flow left ventricular assist device: Osaka University Experience.

    PubMed

    Yoshioka, Daisuke; Matsumiya, Goro; Toda, Koichi; Sakaguchi, Taichi; Yoshikawa, Yasushi; Saito, Shunsuke; Matsuda, Hikaru; Sawa, Yoshiki

    2014-12-01

    The aim of this study was to evaluate our clinical experience with the Jarvik 2000 axial flow pump (Jarvik Heart, Inc, New York, NY, USA), a miniature axial flow left ventricular assist device (LVAD). The clinical results of eight patients, who underwent LVAD implantation with the Jarvik 2000 (median age 55.0 years; six men) between 2005 and 2010, including two who participated in a multicenter clinical trial in Japan, were reviewed. Two patients underwent LVAD implantation as destination therapy. Four patients underwent Jarvik 2000 implantation via median sternotomy, while the other four underwent implantation via left thoracotomy. There were no major complications during surgery. Four patients were supported for more than 2 years. The longest support duration was 1,618 days. Six patients successfully bridged to heart transplantation after a median 725 days of support. One patient on destination therapy died of a cerebral infarction. The other patient on destination therapy had had the LVAD for 1,618 days. The overall survival rates at 1, 2, and 3 years were 100, 86, and 86%, respectively. The median postoperative serum lactate dehydrogenase level was 860.5 U/L at 1 month, 735 U/L at 6 months, and 692 U/L at 1 year. There were no fatal device-related infections. We found that the Jarvik 2000 with pin bearing could support patients with end-stage heart failure with acceptable mortality and morbidity rates. Further evaluations of the prevalence of thromboembolic and hemolytic events in patients with the new conical-bearing Jarvik 2000 are required.

  5. Development of a new modified Bethesda method for coagulation inhibitors: the Osaka modified Bethesda method.

    PubMed

    Torita, Sumiko; Suehisa, Etsuji; Kawasaki, Tomio; Toku, Masayuki; Takeo, Emi; Tomiyama, Yoshiaki; Nishida, Sumiyuki; Hidaka, Yoh

    2011-04-01

    The Nijmegen assay for the factor VIII (F-VIII) inhibitor is recommended by the International Society on Thrombosis and Haemostasis/Scientific and Standardization Committee. However, due to cumbersome and complicated preprocessing, it is presently difficult to introduce this assay into hospital laboratories. We used buffered plasma that was made by addition of 1 volume of 1 mol/l HEPES buffer at pH 7.35 to 9 volumes of plasma to form the test samples. The inhibitor titer was calculated by the remaining rate of F-VIII coagulation activity (F-VIII:C), using the ratio of actual value to the theoretical value. Five hundred microliters of the buffered test plasma and the control (30 mmol/l HEPES buffered saline at pH 7.35) were each mixed with equal volumes (500 μl) of normal pooled plasma in a test tube (11 mm internal diameter and 6.5 ml volume capacity), and incubated at 37°C for 2 h. In our modified Bethesda method, there were no significant changes in pH and F-VIII:C of control and test mixtures after incubation tests for stability. With the modified method, the inhibitor titers (mean, SD) from examining three hemophilia A plasma samples (F-VIII:C, <1-3%) and 40 normal samples (F-VIII:C, 34.5-168.3%) were 0.032, 0.057 and -0.009, 0.057, respectively. By our method, the F-VIII inhibitor titer of type I inhibitor-positive samples was higher than the Nijmegen method, and for type II inhibitor-positive samples, the titer was similar. We believe that our method can be applied to not only the type I inhibitor, but also to assays of type II inhibitor, without cumbersome and complicated preprocessing.

  6. Laser-diode-pumped solid-state laser driver at ILE Osaka

    NASA Astrophysics Data System (ADS)

    Yamanaka, Masanobu; Naito, Kenta; Nakatsuka, Masahiro; Nakai, Sadao

    1992-11-01

    Using a conceptual designing technique developed we evaluate the feasibility of laser diode pumped solid state laser systems which have 1OMJ blue output 10 overall efficiency and 10Hz repetition rate with typical solid state laser materials for the reactor driver from both technical and economical points of view. For an economical laser fusion reactor driver the solid state laser materials are required to have the following properties hw/a 40J/cm2 (hco : the laser photon energy a : the stimulated emission cross section) a thermal shock parameter of <=3W/cm a nonlinear index of refraction smaller than --3x1013 esu and a fluorescence lifetime of <=4ms. 1.

  7. Dry eye disease and work productivity loss in visual display users: the Osaka study.

    PubMed

    Uchino, Miki; Uchino, Yuichi; Dogru, Murat; Kawashima, Motoko; Yokoi, Norihiko; Komuro, Aoi; Sonomura, Yukiko; Kato, Hiroaki; Kinoshita, Shigeru; Schaumberg, Debra A; Tsubota, Kazuo

    2014-02-01

    To estimate the impact of dry eye disease (DED) on work performance and productivity in office workers using visual display terminals (VDTs). Cross-sectional study. Six hundred seventy-two Japanese young and middle-aged office workers using VDTs completed a questionnaire that was designed to measured at-work performance deficits and productivity losses using the Japanese version of the Work Limitations Questionnaire, completed by e-mail. Using the Japanese dry eye diagnostic criteria, respondents were classified into 3 groups: definite DED, probable DED, and non DED. Of the 672 office workers, 553 subjects (82.3%), including 366 men and 187 women, completed the questionnaire and underwent clinical evaluation. As for the total workplace productivity loss, the non DED group demonstrated a loss of 3.56%, those with probable DED demonstrated a loss of 4.06%, and those with definite DED demonstrated a loss of 4.82%, indicating significantly worse performance and productivity (P = .014, trend test). For the 4 subscales, DED was associated with significantly lower on-the-job time management (P = .009, trend test) and combined mental performance and interpersonal functioning (P = .011, trend test). After controlling for age, sex, VDT working hours, and diagnosis of DED, time management, physical demands, and mental and interpersonal functioning showed a significant relationship to DED (each P > .05). Annual DED productivity losses were estimated to be $6160 per employee when measured by total production and $1178 per employee calculated by wage. This study indicated that there is a significant impact of DED on the total productivity of Japanese VDT users. Copyright © 2014 Elsevier Inc. All rights reserved.

  8. Breastfeeding and atopic eczema in Japanese infants: The Osaka Maternal and Child Health Study.

    PubMed

    Miyake, Yoshihiro; Tanaka, Keiko; Sasaki, Satoshi; Kiyohara, Chikako; Ohya, Yukihiro; Fukushima, Wakaba; Yokoyama, Tetsuji; Hirota, Yoshio

    2009-05-01

    Epidemiological studies associated with breastfeeding have provided conflicting results about whether it is preventive or a risk factor for atopic eczema in children. The current prospective study investigated the relationship between breastfeeding and the risk of atopic eczema in Japan. A birth cohort of 763 infants was followed. The first survey during pregnancy and the second survey between 2 and 9 months postpartum collected information on potential confounding factors and atopic eczema status. Data on breastfeeding and symptoms of atopic eczema were obtained from questionnaires in the third survey from 16 to 24 months postpartum. The following variables were a priori selected as potential confounders: maternal age, maternal and paternal history of asthma, atopic eczema, and allergic rhinitis, indoor domestic pets (cats, dogs, birds, or hamsters), family income, maternal and paternal education, maternal smoking during pregnancy, baby's sex, baby's birth weight, baby's older siblings, household smoking in the same room as the infant, and time of delivery before the third survey. In the third survey, 142 infants (18.6%) were revealed to have developed atopic eczema based on criteria of the International Study of Asthma and Allergies in Childhood. In an overall analysis, neither exclusive nor partial breastfeeding was significantly related to the risk of atopic eczema. After excluding 64 infants identified with suspected atopic eczema in the second survey, both exclusive breastfeeding for 4 months or more and partial breastfeeding for 6 months or more were independently associated with an increased risk of atopic eczema only among infants with no parental history of allergic disorders [multivariate odds ratios were 2.41 (95% confidence interval, 1.10-5.55) and 3.39 (95% confidence interval, 1.20-12.36), respectively]. The authors found that, overall, neither exclusive nor partial breastfeeding had a strong impact on the risk of atopic eczema. However, a parental allergic history may affect the risk.

  9. Active Travel by Built Environment and Lifecycle Stage: Case Study of Osaka Metropolitan Area.

    PubMed

    Waygood, E Owen D; Sun, Yilin; Letarte, Laurence

    2015-12-15

    Active travel can contribute to physical activity achieved over a day. Previous studies have examined active travel associated with trips in various western countries, but few studies have examined this question for the Asian context. Japan has high levels of cycling, walking and public transport, similar to The Netherlands. Most studies have focused either on children or on adults separately, however, having children in a household will change the travel needs and wants of that household. Thus, here a household lifecycle stage approach is applied. Further, unlike many previous studies, the active travel related to public transport is included. Lastly, further to examining whether the built environment has an influence on the accumulation of active travel minutes, a binary logistic regression examines the built environment's influence on the World Health Organization's recommendations of physical activity. The findings suggest that there is a clear distinction between the urbanized centers and the surrounding towns and unurbanized areas. Further, active travel related to public transport trips is larger than pure walking trips. Females and children are more likely to achieve the WHO recommendations. Finally, car ownership is a strong negative influence.

  10. Active Travel by Built Environment and Lifecycle Stage: Case Study of Osaka Metropolitan Area

    PubMed Central

    Waygood, E. Owen D.; Sun, Yilin; Letarte, Laurence

    2015-01-01

    Active travel can contribute to physical activity achieved over a day. Previous studies have examined active travel associated with trips in various western countries, but few studies have examined this question for the Asian context. Japan has high levels of cycling, walking and public transport, similar to The Netherlands. Most studies have focused either on children or on adults separately, however, having children in a household will change the travel needs and wants of that household. Thus, here a household lifecycle stage approach is applied. Further, unlike many previous studies, the active travel related to public transport is included. Lastly, further to examining whether the built environment has an influence on the accumulation of active travel minutes, a binary logistic regression examines the built environment’s influence on the World Health Organization’s recommendations of physical activity. The findings suggest that there is a clear distinction between the urbanized centers and the surrounding towns and unurbanized areas. Further, active travel related to public transport trips is larger than pure walking trips. Females and children are more likely to achieve the WHO recommendations. Finally, car ownership is a strong negative influence. PMID:26694429

  11. The effect of choline-stabilized orthosilicic acid on microelements and silicon concentration, photosynthesis activity and yield of tomato grown under Mn stress.

    PubMed

    Kleiber, Tomasz; Calomme, Mario; Borowiak, Klaudia

    2015-11-01

    The aim of experiments was to assess the efficiency of choline-stabilized orthosilicic acid (ch-OSA; complex of orthosilicic acid with choline and a bioavailable source of silicon) application under increasing manganese (Mn) stress on the micronutritional composition and yielding of tomato (Solanum lycopersicum L. cvs. 'Alboney F1' and 'Emotion F1'). Plants were grown in rockwool with the application of a nutrient solution varied the Mn concentrations (in mg dm(-3)): 9.6 and 19.2 which cause strong oxidative stress of plants comparing with optimal concentration of that microelement in nutrient solution. The effect of ch-OSA application (at Si concentration of 0.3 mg dm(-3) nutrient solution) was investigated at both Mn-levels. Increasing Mn stress modified the concentration of microelements and silicon (Si) in tomato leaves. Application of ch-OSA also influenced the concentration of nutrients, but the determined changes were generally multidirectional and varied depending on Mn-level and cultivar. Under the increasing Mn stress a significant downward trend was observed for the mean concentration of Fe (in both cultivars) in fruits--but changes of Mn, Zn and Cu were varied depend on cultivar. In the case of cv. 'Alboney F1' ch-OSA application caused an increase the mean concentrations of Fe, Zn and Cu, while in the case of cv. 'Emotion F1' the reduction of mean concentrations of Zn and Cu was recorded. Ch-OSA treatment did not influence on the Mn concentrations in fruits. A beneficial role of ch-OSA was also found in photosynthesis activity. This was especially valid for lower levels of Mn. Application of ch-OSA improved significantly the marketable yield of tomato under stress by a low Mn level. Copyright © 2015 The Authors. Published by Elsevier Masson SAS.. All rights reserved.

  12. Infant feeding practices and risk of dental caries in Japan: the Osaka Maternal And Child Health Study.

    PubMed

    Tanaka, Keiko; Miyake, Yoshihiro; Sasaki, Satoshi; Hirota, Yoshio

    2013-01-01

    The purpose of this study was to prospectively investigate the association between infant feeding practices and the development of early childhood caries (ECC). Subjects were 315 children. Information about the variables under study and potential confounding factors were obtained by questionnaire during pregnancy and when the children were two to nine, 16 to 24, 29 to 39, and 41 to 49 months old. Outcome data were collected at 41 to 50 months old. Children were classified as having ECC if one or more primary teeth had decayed or been filled. Compared with breast-feeding for six months or fewer, breast-feeding for 18 months or longer tended to be positively associated with a risk of ECC, and a U-shaped relationship was observed. Use of a bottle to drink sweetened liquids other than milk and the introduction of solid foods at six months old or later were positively associated with a risk of ECC. There was no significant association between bottle-feeding while falling asleep at night and the risk of ECC. Prolonged breast-feeding, bottle use for sweetened liquids other than milk, and the introduction of solid foods at six months old or later might be risk factors for the development of dental caries.

  13. [Introduction of hospital information system and anesthesia information management system into the perianesthetic practice at Osaka City University Hospital].

    PubMed

    Shimizu, Motoko; Tanaka, Katsuaki; Hagiwara, Chie; Ikenaga, Kazutake; Yoshioka, Miwako; Asada, Akira

    2011-06-01

    Recently, the hospital information systems (HIS) and anesthesia information management systems (AIMS) have been rapidly improved and have been introduced into the clinical practice in Japan drastically; however, few reports have detailed their influences on clinical practice. We here report our experience. We introduced HIS (EGMAIN-EX, Fujitsu Co., Ltd.) in our preoperative evaluation clinic and in the postoperative care unit. AIMS (ORSYS, Philips Electronics Japan) was introduced almost only to the intraoperative management. It became easy for us to acquire patient's information and to share it with the medical staffs in the other departments. However, we had to invest large human resources for the introduction and maintenance of the HIS and the AIMS. Though AIMS is more useful in anesthetic management than HIS, it seems to be more suitable for coordination with the medical staffs in the other departments to use HIS for perioperative management than to use AIMS.

  14. Breastfeeding and the risk of wheeze and asthma in Japanese infants: the Osaka Maternal and Child Health Study.

    PubMed

    Miyake, Y; Tanaka, K; Sasaki, S; Kiyohara, C; Ohya, Y; Fukushima, W; Yokoyama, T; Hirota, Y

    2008-09-01

    Epidemiological evidence for an effect of breastfeeding on asthma continues to be inconclusive. The present prospective study examined the relationship between breastfeeding and the risk of wheeze and asthma in Japanese infants. A birth cohort of 763 infants was followed. The first survey during pregnancy and the second survey between 2 and 9 months postpartum collected information on potential confounding factors. Data on breastfeeding, wheeze, and asthma were obtained from questionnaires in the third survey from 16 to 24 months postpartum. Adjustment was made for maternal age, maternal and paternal history of asthma, atopic eczema, and allergic rhinitis, indoor domestic pets (cats, dogs, birds, or hamsters), family income, maternal and paternal education, maternal smoking during pregnancy, baby's sex, baby's older siblings, household smoking in the same room as the infant, and time of delivery before the third survey. By the third survey, the cumulative incidence of wheeze and asthma was 22.1% and 4.3%, respectively. Neither exclusive breastfeeding for 4 months or more nor partial breastfeeding for 6 months or more were materially related to the risk of wheeze. No measurable association was observed between exclusive breastfeeding for 4 months or more and the risk of asthma. Partial breastfeeding for 6 months or more was inversely related to the risk of asthma although the adjusted odds ratio (OR) was not statistically significant. When infants were stratified according to whether there was a negative or positive allergic history in at least 1 parent, a nearly 40% and 60% decrease, respectively, in the ORs were found for exclusive and partial breastfeeding only in infants without a parental allergic history, although the ORs were not statistically significant. The present prospective study showed no statistically significant relationship between breastfeeding duration and the risk of wheeze or asthma in Japanese infants.

  15. Maternal dietary patterns in pregnancy and fetal growth in Japan: the Osaka Maternal and Child Health Study.

    PubMed

    Okubo, Hitomi; Miyake, Yoshihiro; Sasaki, Satoshi; Tanaka, Keiko; Murakami, Kentaro; Hirota, Yoshio; Kanzaki, Hideharu; Kitada, Mitsuyoshi; Horikoshi, Yorihiko; Ishiko, Osamu; Nakai, Yuichiro; Nishio, Junko; Yamamasu, Seiichi; Yasuda, Jinsuke; Kawai, Seigo; Yanagihara, Kazumi; Wakuda, Koji; Kawashima, Tokio; Narimoto, Katsuhiko; Iwasa, Yoshihiko; Orino, Katsuhiko; Tsunetoh, Itsuo; Yoshida, Junichi; Iito, Junichi; Kaneko, Takuzi; Kamiya, Takao; Kuribayashi, Hiroyuki; Taniguchi, Takeshi; Takemura, Hideo; Morimoto, Yasuhiko; Matsunaga, Ichiro; Oda, Hajime; Ohya, Yukihiro

    2012-05-01

    Maternal nutritional status during pregnancy is an important determinant of fetal growth. Although the effects of several nutrients and foods have been well examined, little is known about the relationship of overall maternal diet in pregnancy to fetal growth, particularly in non-Western populations. We prospectively examined the relationship of maternal dietary patterns in pregnancy to neonatal anthropometric measurements at birth and risk of small-for-gestational-age (SGA) birth among 803 Japanese women with live-born, singleton, term deliveries. Maternal diet in pregnancy was assessed using a validated, self-administered diet history questionnaire. Dietary patterns from thirty-three predefined food groups (g/4184 kJ) were extracted by cluster analysis. The following three dietary patterns were identified: the 'meat and eggs' (n 326), 'wheat products', with a relatively high intake of bread, confectioneries and soft drinks (n 303), and 'rice, fish and vegetables' (n 174) patterns. After adjustment for potential confounders, women in the 'wheat products' pattern had infants with the significantly lowest birth weight (P = 0·045) and head circumference (P = 0·036) among those in the three dietary patterns. Compared with women in the 'rice, fish and vegetables' pattern, women in the 'wheat products' pattern had higher odds of having a SGA infant for weight (multivariate OR 5·2, 95 % CI 1·1, 24·4), but this was not the case for birth length or head circumference. These results suggest that a diet high in bread, confectioneries, and soft drinks and low in fish and vegetables during pregnancy might be associated with a small birth weight and an increased risk of having a SGA infant.

  16. Dietary patterns during pregnancy and the risk of postpartum depression in Japan: the Osaka Maternal and Child Health Study.

    PubMed

    Okubo, Hitomi; Miyake, Yoshihiro; Sasaki, Satoshi; Tanaka, Keiko; Murakami, Kentaro; Hirota, Yoshio

    2011-04-01

    Although several nutrients and foods are suggested to be preventive against postpartum depression, all previous studies have primarily focused on single nutrients or foods. In contrast, studies on dietary patterns, namely the measurement of overall diet by considering the cumulative effects of nutrient, may provide new insights into the influence of diet on postpartum depression. We prospectively examined the association between dietary patterns during pregnancy and the risk of postpartum depression among 865 Japanese women. Diet was assessed with a validated, self-administered diet history questionnaire. Dietary patterns from thirty-three predefined food groups (energy-adjusted food (g/d)) were extracted by factor analysis. Postpartum depression was defined as present when the subjects had an Edinburgh Postnatal Depression Scale score of ≥ 9 at 2-9 months postpartum. A total of 121 women (14·0 %) were classified as having postpartum depression. Three dietary patterns were identified: 'Healthy', 'Western' and 'Japanese' patterns. After adjustment for potential confounders, neither the 'Healthy' nor the 'Japanese' pattern was related to the risk of postpartum depression. Compared with the first quartile of the 'Western' pattern, only the second quartile was independently related to a decreased risk of postpartum depression (multivariate OR 0·52, 95 % CI 0·30, 0·93), although no evident exposure-response associations were observed (P for trend = 0·36). The present study failed to substantiate clear associations between dietary patterns and the risk of postpartum depression. Further studies with more accurate measurements are warranted to confirm the relationship between dietary patterns and the risk of postpartum depression.

  17. Commercialization of biotechnology in the Asian region. Report of meeting of Asian Productivity Organization (APO) in Osaka, Japan.

    PubMed

    Rogers, P L

    1990-01-01

    Detailed studies on the commercial development of biotechnology in five countries in the Asian Region (viz. Japan, Korea, Taiwan, Thailand, India) indicate a very significant role played by government in strategic planning and R & D financing. Strong growth is projected in some traditional biotechnology products e.g. amino acids such as monosodium glutamate and L-lysine, animal and human vaccines, and in environmental applications of biotechnology. The cash flow from these products will underpin future development and marketing of diagnostics, anticancer and antiviral drugs, particularly in Japan and Korea.

  18. Socioeconomic status and risk of dental caries in Japanese preschool children: the Osaka Maternal and child health study.

    PubMed

    Tanaka, Keiko; Miyake, Yoshihiro; Sasaki, Satoshi; Hirota, Yoshio

    2013-01-01

    Investigations concerning the relationship between socioeconomic status and dental caries have been conducted mainly in Western countries. The purpose of this longitudinal study was to examine the impact of socioeconomic factors, such as maternal occupation, household income, and parental educational levels, on the risk of dental caries in young Japanese children. A cohort of 315 preschool children was used. Information pertaining to exposure and potentially confounding factors was obtained by means of questionnaires administered to expectant mothers prior to delivery and subsequently when their children were in the ranges of 2-9, 16-24, 29-39, and 41-49 months of age. Outcome data were collected when the children were between 41 and 50 months old. Children were classified as having dental caries if one or more primary teeth had decayed or had been filled. Compared with maternal or paternal education of less than 13 years, maternal or paternal education of 15 years or longer was significantly associated with a decreased risk of dental caries in children: the adjusted odds ratios for maternal and paternal education levels ≥ 15 years compared with <13 years of maternal and paternal education were 0.32 (95 percent confidence interval: 0.14-0.71) and 0.45 (95 percent confidence interval: 0.23-0.88), respectively. No relationship between maternal occupation or household income and the risk of children's dental caries was found. Higher levels of parental education, in particular maternal education, may be associated with reduced risk of dental caries in preschool children. © 2013 American Association of Public Health Dentistry.

  19. Prevalence of Norwalk-Like Virus Infections in Cases of Viral Gastroenteritis among Children in Osaka City, Japan

    PubMed Central

    Iritani, Nobuhiro; Seto, Yoshiyuki; Kubo, Hideyuki; Murakami, Tsukasa; Haruki, Kosuke; Ayata, Minoru; Ogura, Hisashi

    2003-01-01

    Surveillance of Norwalk-like virus (NLV) infections in cases of pediatric gastroenteritis between April 1996 and March 2000 showed that NLVs were an important causative agent in viral gastroenteritis cases among children between November and January in those years. The predominant type of NLV was closely related to Lordsdale virus in genogroup 2. During the 1999-2000 season, Arg320-like strains, which may be genetic recombinants, suddenly appeared and spread. PMID:12682179

  20. Prevalence of Norwalk-like virus infections in cases of viral gastroenteritis among children in Osaka City, Japan.

    PubMed

    Iritani, Nobuhiro; Seto, Yoshiyuki; Kubo, Hideyuki; Murakami, Tsukasa; Haruki, Kosuke; Ayata, Minoru; Ogura, Hisashi

    2003-04-01

    Surveillance of Norwalk-like virus (NLV) infections in cases of pediatric gastroenteritis between April 1996 and March 2000 showed that NLVs were an important causative agent in viral gastroenteritis cases among children between November and January in those years. The predominant type of NLV was closely related to Lordsdale virus in genogroup 2. During the 1999-2000 season, Arg320-like strains, which may be genetic recombinants, suddenly appeared and spread.

  1. Choline-stabilized orthosilicic acid supplementation as an adjunct to Calcium/Vitamin D3 stimulates markers of bone formation in osteopenic females: a randomized, placebo-controlled trial

    PubMed Central

    Spector, Tim D; Calomme, Mario R; Anderson, Simon H; Clement, Gail; Bevan, Liisa; Demeester, Nathalie; Swaminathan, Rami; Jugdaohsingh, Ravin; Berghe, Dirk A Vanden; Powell, Jonathan J

    2008-01-01

    Background Mounting evidence supports a physiological role for silicon (Si) as orthosilicic acid (OSA, Si(OH)4) in bone formation. The effect of oral choline-stabilized orthosilicic acid (ch-OSA) on markers of bone turnover and bone mineral density (BMD) was investigated in a double-blind placebo-controlled trial. Methods Over 12-months, 136 women out of 184 randomized (T-score spine < -1.5) completed the study and received, daily, 1000 mg Ca and 20 μg cholecalciferol (Vit D3) and three different ch-OSA doses (3, 6 and 12 mg Si) or placebo. Bone formation markers in serum and urinary resorption markers were measured at baseline, and after 6 and 12 months. Femoral and lumbar BMD were measured at baseline and after 12 months by DEXA. Results Overall, there was a trend for ch-OSA to confer some additional benefit to Ca and Vit D3 treatment, especially for markers of bone formation, but only the marker for type I collagen formation (PINP) was significant at 12 months for the 6 and 12 mg Si dose (vs. placebo) without a clear dose response effect. A trend for a dose-corresponding increase was observed in the bone resorption marker, collagen type I C-terminal telopeptide (CTX-I). Lumbar spine BMD did not change significantly. Post-hoc subgroup analysis (baseline T-score femur < -1) however was significant for the 6 mg dose at the femoral neck (T-test). There were no ch-OSA related adverse events observed and biochemical safety parameters remained within the normal range. Conclusion Combined therapy of ch-OSA and Ca/Vit D3 had a potential beneficial effect on bone collagen compared to Ca/Vit D3 alone which suggests that this treatment is of potential use in osteoporosis. NTR 1029 PMID:18547426

  2. Chronotherapy for hypertension in obstructive sleep apnoea (CHOSA): a randomised, double-blind, placebo-controlled crossover trial.

    PubMed

    Serinel, Yasmina; Yee, Brendon J; Grunstein, Ronald R; Wong, Keith H; Cistulli, Peter A; Arima, Hisatomi; Phillips, Craig L

    2017-06-01

    Obstructive sleep apnoea (OSA) is an important cause of secondary hypertension. Nocturnal hypertension is particularly prevalent in OSA and is a strong predictor of cardiovascular mortality. Studies in patients with essential hypertension have suggested that nocturnal administration of antihypertensives improves nocturnal blood pressure (BP) without elevating daytime BP. We evaluated the efficacy of this technique in patients with OSA with stage I/II hypertension, both before and after the addition of CPAP. In this double-blind randomised placebo-controlled crossover trial, patients with moderate-to-severe OSA and hypertension received 6 weeks each of evening or morning perindopril with opposing time-matched placebo. CPAP therapy was subsequently added for 8 weeks in addition to either morning or evening perindopril. The primary outcome was sleep systolic BP (SBP) using 24-hour BP monitoring, analysed using linear mixed models. Between March 2011 and January 2015, 85 patients were randomised, 79 completed both dosing times, 78 completed the CPAP phase. Sleep SBP reduced significantly from baseline with both evening (-6.9 mm Hg) and morning (-8.0 mm Hg) dosing, but there was no difference between dosing times (difference: 1.1 mm Hg, 95% CI -0.3 to 2.5). However, wake SBP reduced more with morning (-9.8 mm Hg) than evening (-8.0 mm Hg) dosing (difference: 1.8 mm Hg, 95% CI 1.1 to 2.5). Addition of CPAP to either evening or morning dosing further reduced sleep SBP, but by a similar amount (evening: -3.2 mm Hg, 95% CI -5.1 to -1.3; morning: -3.3 mm Hg, 95% CI -5.2 to 1.5). Our findings support combining OSA treatment with morning administration of antihypertensives. Unlike in essential hypertension, our results do not support evening administration of antihypertensives, at least with perindopril. Further research is required before this strategy can be widely adopted into hypertension guidelines and clinical practice. ACTRN12611000216910, Results. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  3. The Selling of the Taj Mahal or Osaka Castle. 7th Grade Lesson. Schools of California Online Resources for Education (SCORE): Connecting California's Classrooms to the World.

    ERIC Educational Resources Information Center

    Dyer, Bill

    In this lesson, student teams role-play as real estate agents who have been contacted by an art collector about purchasing a large historic landmark in which to house an art collection. Teams will research an historical site and prepare a creative sales presentation. Students are provided with background information, detailed instructions, on-line…

  4. Fitness for the Aged, Disabled, and Industrial Worker. Proceedings of the Symposium of the International Council for Physical Fitness Research (Osaka, Japan, September 5-7, 1988).

    ERIC Educational Resources Information Center

    Kaneko, Masahiro, Ed.

    This comprehensive collection of current research on the health and fitness of the aged, the disabled, and the industrial worker examines the growing health problems in those populations. These problems are the result of the rising proportion of elderly and disabled citizens in Western countries and the increasing exposure of industrial workers to…

  5. Maternal total caffeine intake, mainly from Japanese and Chinese tea, during pregnancy was associated with risk of preterm birth: the Osaka Maternal and Child Health Study.

    PubMed

    Okubo, Hitomi; Miyake, Yoshihiro; Tanaka, Keiko; Sasaki, Satoshi; Hirota, Yoshio

    2015-04-01

    The relation of maternal caffeine intake with birth outcomes is still inconclusive and has not been examined in Japan, where the sources of caffeine intake are different from those in Western countries. We hypothesized that maternal consumption of total caffeine and culture-specific major sources of caffeine would be associated with birth outcomes among Japanese pregnant. The study subjects were 858 Japanese women who delivered singleton infants. Maternal diet during pregnancy was assessed using a validated, self-administered diet history questionnaire. Birth outcomes considered were low birth weight (LBW; <2500 g), preterm birth (PTB; <37 weeks of gestation), and small for gestational age (SGA; <10th percentile). The main caffeine sources were Japanese and Chinese tea (73.5%), coffee (14.3%), black tea (6.6%), and soft drinks (3.5%). After controlling for confounders, maternal total caffeine intake during pregnancy was significantly associated with an increased risk of PTB (odds ratio per 100 mg/d caffeine increase, 1.28; 95% confidence interval, 1.03-1.58; P for trend = .03). However, no evident relationships were observed between total caffeine intake and risk of LBW or SGA. As for caffeine sources, higher Japanese and Chinese tea consumption was associated with an increased risk of PTB (odds ratio per 1 cup/d increase, 1.14; 95% confidence interval, 1.00-1.30; P for trend = .04), but not LBW or SGA. There were no associations between consumption of the other beverages examined and birth outcomes. In conclusion, this prospective birth cohort in Japan suggests that higher maternal total caffeine intake, mainly in the form of Japanese and Chinese tea, during pregnancy is associated with a greater risk of PTB. Copyright © 2015 Elsevier Inc. All rights reserved.

  6. Education, but not occupation or household income, is positively related to favorable dietary intake patterns in pregnant Japanese women: the Osaka Maternal and Child Health Study.

    PubMed

    Murakami, Kentaro; Miyake, Yoshihiro; Sasaki, Satoshi; Tanaka, Keiko; Ohya, Yukihiro; Hirota, Yoshio

    2009-03-01

    Although a large body of epidemiologic data accumulated in Western countries show that individuals with a higher socioeconomic position consume higher quality diets, information on such socioeconomic differences in the diets of non-Western populations, including Japanese, is absolutely lacking. This cross-sectional study examined the association of socioeconomic position with dietary intake in a group of pregnant Japanese women. Subjects were 1002 Japanese women during pregnancy. Socioeconomic position was assessed by education, occupation, and household income. Dietary intake was estimated using a validated, self-administered, comprehensive diet history questionnaire. Education was associated positively with intake of protein; total n-3 and marine-origin n-3 polyunsaturated fatty acids; dietary fiber; cholesterol; potassium; calcium; magnesium; iron; vitamins A, D, E, and C; and folate 9 and inversely with that of carbohydrate. No associations were seen between education and intake of total fat; saturated, monounsaturated, and total and n-6 polyunsaturated fatty acids; alcohol; or sodium. Regarding food, higher education was associated with a higher intake of vegetables, fish and shellfish, and potatoes and lower intake of rice. Education was not associated with intake of bread, noodles, confectioneries and sugars, fats and oils, pulses and nuts, meat, eggs, dairy products, or fruit. For occupation, housewives had a higher intake of dietary fiber, magnesium, iron, vitamin A, folate, and pulses and nuts than working women. Household income was not associated with any nutrient or food examined. In conclusion, education, but not occupation or household income, was positively associated with favorable dietary intake patterns in a group of pregnant Japanese women.

  7. Monetary Diet Cost is Associated with not only Favorable but also Unfavorable Aspects of Diet in Pregnant Japanese Women: The Osaka Maternal and Child Health Study.

    PubMed

    Murakami, Kentaro; Miyake, Yoshihiro; Sasaki, Satoshi; Tanaka, Keiko; Ohya, Yukihiro; Hirota, Yoshio

    2009-05-12

    While several observational studies in European countries have shown that higher monetary diet cost is associated with healthier diets, information on the relationship of cost to diet quality in other countries is sparse, including Japan. This cross-sectional study examined the association between monetary diet cost and dietary intake in a group of pregnant Japanese women. Subjects were 596 pregnant Japanese housewives. Dietary intake was estimated using a validated, self-administered, comprehensive diet history questionnaire. Monetary diet cost was calculated using retail food prices. Values of monetary diet cost and nutrient and food intake were energy-adjusted using the density method. Monetary diet cost was associated positively with the intake of protein, total fat, saturated fatty acids, dietary fiber, cholesterol, sodium, potassium, calcium, magnesium, iron, vitamins A, D, E, C, and folate, and inversely with that of carbohydrate. For foods, cost was associated positively with the intake of potatoes, pulses and nuts, fish and shellfish, meat, dairy products, vegetables, and fruits, and inversely with that of rice and bread. No association was seen for noodles, confectioneries and sugars, fats and oils, or eggs. Cost was also associated inversely with dietary energy density. In conclusion, monetary diet cost was associated with not only favorable aspects of diet, including a higher intake of dietary fiber, key vitamins and minerals, fruits, and vegetables and lower dietary energy density, but also unfavorable aspects, including a higher intake of fat and sodium and lower intake of carbohydrate and rice, in a group of pregnant Japanese women.

  8. Scheduled endoscopic surveillance controls secondary cancer after curative endoscopic resection for early gastric cancer: a multicentre retrospective cohort study by Osaka University ESD study group.

    PubMed

    Kato, Motohiko; Nishida, Tsutomu; Yamamoto, Katsumi; Hayashi, Shiro; Kitamura, Shinji; Yabuta, Takamasa; Yoshio, Toshiyuki; Nakamura, Takeshi; Komori, Masato; Kawai, Naoki; Nishihara, Akihiro; Nakanishi, Fumihiko; Nakahara, Masanori; Ogiyama, Hideharu; Kinoshita, Kazuo; Yamada, Takuya; Iijima, Hideki; Tsujii, Masahiko; Takehara, Tetsuo

    2013-10-01

    After endoscopic submucosal dissection (ESD) of early gastric cancer (EGC), patients are at high risk for synchronous or metachronous multiple gastric cancers. To elucidate the time at which multiple cancers develop and to determine whether scheduled endoscopic surveillance might control their development. A multicentre retrospective cohort study from 12 hospitals was conducted. Patients with EGC who underwent ESD with en bloc margin-negative curative resection were included. Synchronous cancer was classified as concomitant cancer or missed cancer. The cumulative incidence of metachronous cancers and overall survival rate were calculated using the Kaplan-Meier method. From April 1999 to December 2010, 1258 patients met the inclusion criteria. Synchronous or metachronous multiple cancers were detected in 175 patients (13.9%) during a mean of 26.8 months. Among the 110 synchronous cancers, 21 were missed at the time of the initial ESD. Many of the missed lesions existed in the upper third of the stomach and the miss rate was associated with the endoscopist's inexperience (<500 oesophagogastroduodenoscopy cases). The cumulative incidence of metachronous cancers increased linearly and the mean annual incidence rate was 3.5%. The incidence rate did not differ between patients with or without Helicobacter pylori eradication. Four lesions (0.32%) were detected as massively invading cancers during the follow-up. Nineteen per cent of synchronous cancers were not detected until the initial ESD. The incidence rate of metachronous cancer after ESD was constant. Scheduled endoscopic surveillance showed that almost all recurrent lesions were treatable by endoscopic resection.

  9. Gastric ESD under Heparin Replacement at High-Risk Patients of Thromboembolism Is Technically Feasible but Has a High Risk of Delayed Bleeding: Osaka University ESD Study Group.

    PubMed

    Yoshio, Toshiyuki; Nishida, Tsutomu; Kawai, Naoki; Yuguchi, Kiyonori; Yamada, Takuya; Yabuta, Takamasa; Komori, Masato; Yamaguchi, Shinjiro; Kitamura, Shinji; Iijima, Hideki; Tsutsui, Shusaku; Michida, Tomoki; Mita, Eiji; Tsujii, Masahiko; Takehara, Tetsuo

    2013-01-01

    Objectives. Heparin replacement (HR) is often performed in patients with a high risk of thrombosis undergoing endoscopic procedures. However, information about the influence of HR is scarce. The aim of this study is to assess the clinical impact of HR for gastric endoscopic submucosal dissection (ESD). Methods. This is a retrospective study comprising approximately 1310 consecutive gastric neoplasms in 1250 patients, who underwent ESD in 5 institutes. We assessed the clinical findings and outcomes of ESD under HR, compared to ESD without HR as control. Results. A total of 24 EGC lesions in 24 patients were treated by ESD under HR. In the HR group, the complete en-bloc resection rate was 100%. The delayed bleeding rate was, however, higher in the HR group than in the controls (38% versus 4.6%). The timing of bleeding in the HR group was significantly later than in controls. In the control group, 209 patients discontinued antithrombotic therapy during perioperative period, and their delayed bleeding rate was not different from those without antithrombotic therapy (5.7% versus. 4.4%). A thromboembolic event was encountered in 1 patient under HR after delayed bleeding. Conclusion. ESD under HR is technically feasible but has a high risk of delayed bleeding.

  10. Maternal smoking and environmental tobacco smoke exposure and the risk of allergic diseases in Japanese infants: the Osaka Maternal and Child Health Study.

    PubMed

    Tanaka, Keiko; Miyake, Yoshihiro; Sasaki, Satoshi; Ohya, Yukihiro; Hirota, Yoshio

    2008-11-01

    It remains controversial whether environmental tobacco smoke increases the risk of allergic diseases. The present prospective cohort study examined whether in utero exposure to maternal smoking and postnatal exposure to environmental tobacco smoke were associated with the development of wheeze, asthma, and atopic eczema in Japanese infants. Study subjects included 763 infants. Data were obtained through the use of questionnaires completed by the mother during pregnancy and at 2 to 9 and 16 to 24 months postdelivery. Information regarding maternal smoking during pregnancy and postnatal exposure to environmental tobacco smoke was collected at 2 to 9 months postdelivery, and information on allergic symptoms was collected when the infant was between 16 to 24 months of age. Cases were defined according to criteria of the International Study of Asthma and Allergies in Childhood for wheeze and atopic eczema. Additionally, doctor-diagnosed asthma and atopic eczema were identified. Adjustment was made for maternal age, family income, maternal and paternal education, parental history of asthma, atopic eczema, allergic rhinitis, indoor domestic pets, baby's older siblings, baby's sex, birth weight, and time of surveys. The cumulative incidence of wheeze, atopic eczema, doctor-diagnosed asthma, and doctor-diagnosed atopic eczema was 22.1%, 18.6%, 4.3%, and 9.0%, respectively. Maternal smoking during pregnancy was not related to the risk of wheeze, whereas postnatal maternal smoking in the same room as the child increased the risk of wheeze. No significant association was observed between perinatal tobacco smoke exposure and the development of asthma and atopic eczema. Our findings suggest that postnatal maternal smoking might be associated with an increased risk of wheeze in Japanese infants.

  11. Monetary Diet Cost is Associated with not only Favorable but also Unfavorable Aspects of Diet in Pregnant Japanese Women: The Osaka Maternal and Child Health Study

    PubMed Central

    Murakami, Kentaro; Miyake, Yoshihiro; Sasaki, Satoshi; Tanaka, Keiko; Ohya, Yukihiro; Hirota, Yoshio

    2009-01-01

    While several observational studies in European countries have shown that higher monetary diet cost is associated with healthier diets, information on the relationship of cost to diet quality in other countries is sparse, including Japan. This cross-sectional study examined the association between monetary diet cost and dietary intake in a group of pregnant Japanese women. Subjects were 596 pregnant Japanese housewives. Dietary intake was estimated using a validated, self-administered, comprehensive diet history questionnaire. Monetary diet cost was calculated using retail food prices. Values of monetary diet cost and nutrient and food intake were energy-adjusted using the density method. Monetary diet cost was associated positively with the intake of protein, total fat, saturated fatty acids, dietary fiber, cholesterol, sodium, potassium, calcium, magnesium, iron, vitamins A, D, E, C, and folate, and inversely with that of carbohydrate. For foods, cost was associated positively with the intake of potatoes, pulses and nuts, fish and shellfish, meat, dairy products, vegetables, and fruits, and inversely with that of rice and bread. No association was seen for noodles, confectioneries and sugars, fats and oils, or eggs. Cost was also associated inversely with dietary energy density. In conclusion, monetary diet cost was associated with not only favorable aspects of diet, including a higher intake of dietary fiber, key vitamins and minerals, fruits, and vegetables and lower dietary energy density, but also unfavorable aspects, including a higher intake of fat and sodium and lower intake of carbohydrate and rice, in a group of pregnant Japanese women. PMID:20508755

  12. Fitness for the Aged, Disabled, and Industrial Worker. Proceedings of the Symposium of the International Council for Physical Fitness Research (Osaka, Japan, September 5-7, 1988).

    ERIC Educational Resources Information Center

    Kaneko, Masahiro, Ed.

    This comprehensive collection of current research on the health and fitness of the aged, the disabled, and the industrial worker examines the growing health problems in those populations. These problems are the result of the rising proportion of elderly and disabled citizens in Western countries and the increasing exposure of industrial workers to…

  13. Feeding practices in early life and later intake of fruit and vegetables among Japanese toddlers: the Osaka Maternal and Child Health Study.

    PubMed

    Okubo, Hitomi; Miyake, Yoshihiro; Sasaki, Satoshi; Tanaka, Keiko; Hirota, Yoshio

    2016-03-01

    A growing body of evidence from Western countries shows that infant feeding practices are associated with later childhood dietary habits, but little is known about these relationships in non-Western countries with different food cultures. We examined the association of breast-feeding duration and age at introduction of solid foods with later intake of fruit and vegetables among Japanese toddlers. Information on breast-feeding duration, age at introduction of solid foods and child's intake frequency of fruit and vegetables were collected with a self-administered questionnaire at 16-24 months postpartum. Logistic regression analysis was used to calculate odds ratios of low intake (<1 time/d) of fruit or vegetables for each infant feeding practice. Japan. Japanese mother-child pairs (n 763) from a prospective birth cohort study. Neither breast-feeding duration nor age at introduction of solid foods was associated with fruit intake at 16-24 months of age. Breast-feeding duration, but not age at introduction of solid foods, was associated with later intake of vegetables. When breast-feeding duration was categorized into two groups with the cut-off at 6 months, children who were breast-fed for ≥6 months had a significantly decreased risk of low intake of vegetables (OR=0·53; 95% CI 0·34, 0·84) than those breast-fed for <6 months. This association was independent of potential confounders including maternal education and maternal vegetable intake (OR=0·59; 95% CI 0·36, 0·97). This finding suggests that ≥6 months of breast-feeding may prevent low intake of vegetables in early childhood among Japanese toddlers.

  14. Dietary patterns in infancy and their associations with maternal socio-economic and lifestyle factors among 758 Japanese mother-child pairs: the Osaka Maternal and Child Health Study.

    PubMed

    Okubo, Hitomi; Miyake, Yoshihiro; Sasaki, Satoshi; Tanaka, Keiko; Murakami, Kentaro; Hirota, Yoshio

    2014-04-01

    Dietary habits established in early childhood contribute to lifelong dietary pattern and the development of early risk factors for disease in adulthood. Although a large body of epidemiologic data from Western countries show that the dietary pattern of children is influenced by maternal socio-economic and lifestyle characteristics, information on this topic in non-Western countries is absolutely lacking. The present study identified dietary patterns among infants aged 16-24 months, and then examined the influence of maternal socio-economic and lifestyle characteristics on identified dietary patterns. Subjects were 758 Japanese mother-child pairs. Dietary data of infants were collected from the mothers using a questionnaire. Dietary patterns were extracted from the consumption of 15 foods (times week(-1)) by cluster analysis. The following two dietary patterns were identified: 'fruits, vegetables and high-protein foods' (n = 483) and 'confectionaries and sweetened beverages' (n = 275) patterns. After adjustment for all other predictors, maternal educational level, number of infants' siblings and maternal dietary patterns were independently associated with dietary patterns of infants. Infants whose mothers had a higher educational level and the 'rice, fish and vegetables' dietary pattern were less likely to belong to the 'confectionaries and sweetened beverages' pattern, whereas infants whose mothers had a higher number of children and the 'wheat product' dietary pattern were more likely to belong to the 'confectionaries and sweetened beverages' than the 'fruits, vegetables and high-protein foods' pattern. In conclusion, the mother's socio-economic position and dietary patterns were associated with the dietary patterns of infants in the Japanese pairs as observed in the Western populations.

  15. Specific Properties of Enteropathogenic Escherichia coli Isolates from Diarrheal Patients and Comparison to Strains from Foods and Fecal Specimens from Cattle, Swine, and Healthy Carriers in Osaka City, Japan

    PubMed Central

    Wang, Lili; Wakushima, Mitsuko; Aota, Tetsu; Yoshida, Yuka; Kita, Toshimasa; Maehara, Tomofumi; Ogasawara, Jun; Choi, Changsun; Kamata, Yoichi; Hara-Kudo, Yukiko

    2013-01-01

    For exhaustive detection of diarrheagenic Escherichia coli, we previously developed a colony-hybridization method using hydrophobic grid-membrane filters in combination with multiplex real-time PCR. To assess the role of domestic animals as the source of atypical enteropathogenic E. coli (aEPEC), a total of 679 samples (333 from foods, fecal samples from 227 domestic animals, and 119 from healthy people) were examined. Combining 48 strains previously isolated from patients and carriers, 159 aEPEC strains were classified by phylogroup, virulence profile, and intimin typing. Phylogroup B1 was significantly more prevalent among aEPEC from patients (50%) and bovine samples (79%) than from healthy carriers (16%) and swine strains (23%), respectively. Intimin type β1 was predominant in phylogroup B1; B1-β1 strains comprised 26% of bovine strains and 25% of patient strains. The virulence profile groups Ia and Ib were also observed more frequently among bovine strains than among porcine strains. Similarly, virulence group Ia was detected more frequently among patient strains than strains of healthy carriers. A total of 85 strains belonged to virulence group I, and 63 of these strains (74%) belonged to phylogroup B1. The present study suggests that the etiologically important aEPEC in diarrheal patients could be distinguished from aEPEC strains indigenous to humans based on type, such as B1, Ia, and β1/γ1, which are shared with bovine strains, while the aEPEC strains in healthy humans are different, and some of these were also present in porcine samples. PMID:23220963

  16. Experimental analysis of neutron and background gamma-ray energy spectra of 80-400 MeV 7Li(p,n) reactions under the quasi-monoenergetic neutron field at RCNP, Osaka University

    NASA Astrophysics Data System (ADS)

    Iwamoto, Yosuke; Sato, Tatsuhiko; Satoh, Daiki; Hagiwara, Masayuki; Yashima, Hiroshi; Masuda, Akihiko; Matsumoto, Tetsuro; Iwase, Hiroshi; Shima, Tatsushi; Nakamura, Takashi

    2017-09-01

    To develop the 100-400 MeV quasi-monoenergetic neutron field, we measured neutron and unexpected gamma-ray energy spectra of the 7Li(p,n) reaction with 80-389 MeV protons in the 100-m time-of-flight (TOF) tunnel at the Research Center for Nuclear Physics (RCNP) cyclotron facility. Neutron energy spectra with energies above 3 MeV were measured by the TOF method, which had been reported in our previous papers, and photon energy spectra with energies above 0.1 MeV were measured by the automatic unfolding function of the radiation dose monitor DARWIN. For neutron spectra, the contribution of peak intensity to the total intensity integrated with energies above 3 MeV varied between 0.38 and 0.48 in the proton energy range of 80-389 MeV. For gamma-ray spectra, highenergetic gamma-rays at around 70 MeV originated from the decay of π0 were observed with proton energies higher than 200 MeV. For the 246-MeV proton incident reaction, the contribution of gamma-ray dose to neutron dose is negligible because the ratio of gamma-ray dose to neutron dose is 0.014.

  17. Early sugar-sweetened beverage consumption frequency is associated with poor quality of later food and nutrient intake patterns among Japanese young children: the Osaka Maternal and Child Health Study.

    PubMed

    Okubo, Hitomi; Miyake, Yoshihiro; Sasaki, Satoshi; Tanaka, Keiko; Hirota, Yoshio

    2016-06-01

    Evidence from Western countries shows that higher consumption of sugar-sweetened beverages (SSBs) is associated with lower quality of young children's diets, but little is known about these relations in non-Western countries with relatively low consumption levels of SSBs. We hypothesized that SSB consumption in infancy would be associated with poor quality of later food and nutrient intake patterns among Japanese young children. The study subjects were 493 Japanese mother-child pairs from a prospective birth cohort study. Dietary data on children were collected from the mothers using self-administered questionnaires when the children were aged 16-24 months and 41-49 months. Multiple linear regression analyses were used to examine the relationships between SSB consumption frequency in infancy and later intake of foods and nutrients. At 16-24 months of age, more than half of the children (56.4%) consumed SSBs less than once a week, whereas 11.6% consumed SSBs at least once daily. More frequent consumption of SSBs in infancy was associated with higher intake of confectionaries and SSBs and lower intake of fruits and vegetables at 41-49 months of age. These associations were still evident after adjustment for maternal SSB consumption and socioeconomic status. At the nutrient level, SSB consumption frequency was positively associated with energy intake and inversely associated with intake of many nutrients, such as protein, dietary fiber, and most of the micronutrients examined. In conclusion, higher consumption frequency of SSBs at an early age is associated with poor quality of overall dietary intake among young Japanese children 1.5-2.5 years later. Copyright © 2016 Elsevier Inc. All rights reserved.

  18. Characterization of specific alleles in InlA and PrfA of Listeria monocytogenes isolated from foods in Osaka, Japan and their ability to invade Caco-2 cells.

    PubMed

    Kanki, Masashi; Naruse, Hisayo; Taguchi, Masumi; Kumeda, Yuko

    2015-10-15

    Listeria monocytogenes expresses the surface protein internalin A (InlA), enabling the invasion of human intestinal epithelial cells to cause severe food-borne diseases. Full-length sequence analysis of inlA of 114 food isolates resulted in the detection of 29 isolates with a premature stop codon (PMSC) mutation and 6 isolates with 3-codon deletion mutations (aa 738 to 740) in inlA. The isolates with inlA PMSCs demonstrated a significantly lower level of invasion than the other food isolates in a Caco-2 cell invasion assay (P<0.01), but the isolates with the 3-codon deletion exhibited invasion comparable to the isolates with non-truncated InlA (P>0.05). According to analysis of the positive regulatory factor A (PrfA) sequences of 114 L. monocytogenes isolates, 7 isolates of serotype 1/2a from chicken samples contained a PrfA protein with a 5-nucleotide deletion from 712 to 716, including a stop codon. Although the isolates with a 5-nucleotide deletion in prfA demonstrated invasion comparable to the isolates with non-truncated InlA and PrfA after growth at 30 °C (P>0.05), they exhibited a significantly higher level of invasion than the other isolates after growth at 20 °C (P<0.01). To the authors' knowledge, this is the first report of L. monocytogenes isolates with the stop-codon deletion of PrfA. Copyright © 2015 Elsevier B.V. All rights reserved.

  19. Shielding experiments of concrete and iron for the 244 MeV and 387 MeV quasi-mono energetic neutrons using a Bonner sphere spectrometer (at RCNP, Osaka Univ.)

    NASA Astrophysics Data System (ADS)

    Matsumoto, Tetsuro; Masuda, Akihiko; Nishiyama, Jun; Iwase, Hiroshi; Iwamoto, Yosuke; Satoh, Daiki; Hagiwara, Masayuki; Yashima, Hiroshi; Shima, Tatsushi; Nakamura, Takashi; Harano, Hideki; Tamii, Atsushi; Hatanaka, Kichiji

    2017-09-01

    Neutron energy spectra behind concrete and iron shields were measured for quasi-monoenergetic neutrons above 200 MeV using a Bonner sphere spectrometer (BSS). Quasi-monoenergetic neutrons were produced by the 7Li(p,xn) reaction with 246-MeV and 389-MeV protons. Shielding materials are concrete blocks with thicknesses from 25 cm to 300 cm and iron blocks with thicknesses from 10 cm to 100 cm. The response function of BSS was also measured at neutron energies from 100 MeV to 387 MeV. In data analysis, the measured response function was used and the pingpong scattering effect between the BSS and the shielding material was considered. The neutron energy spectra behind the concrete and iron shields were obtained by the unfolding method using the MAXED code. Ambient dose equivalents were obtained as a function of a shield thickness successfully.

  20. Large-Scale Molecular Gas Survey in 12CO, 13CO and C18O (J=2-1) with the Osaka 1.85m mm-submm Telescope

    NASA Astrophysics Data System (ADS)

    Onishi, Toshikazu; Nishimura, Atsushi; Tokuda, Kazuki; Harada, Ryohei; Dobashi, Kazuhito; Shimoikura, Tomomi; Kimura, Kimihiro; Ogawa, Hideo

    2015-08-01

    Molecular clouds are sites of star formation, and rotational transition lines of carbon monoxide (CO) have been widely used to investigate the distribution, physical properties, and kinematics to understand the star formation process in the Galaxy and external galaxies. Although J=1-0 lines of CO are powerful tools to investigate the mass of molecular content of the interstellar medium, the other transitions with different critical densities for the excitation are needed to investigate the local density and temperature, which are important to know the evolutionary status of molecular clouds. We have thus developed a new mm-submm telescope with a diameter of 1.85m installed at the Nobeyama Radio Observatory (Onishi et al. 2013). The scientific goal is to precisely reveal physical properties of molecular clouds in the Galaxy by obtaining a large-scale distribution of molecular gas, which also can be compared with large-scale observations in various wavelengths. The target frequency is ~230 GHz; simultaneous observations in J=2-1 lines of 12CO, 13CO, C18O are achieved with a beam size (HPBW) of 2.7 arcmin. Currently, about 1500 square degrees are covered including the galactic plane (L = 5° ~ 220° with |B| ≤ 1° and star forming regions (Orion, Taurus, Cygnus OB7/X, Opuichus, Aquila and so on). The observations of Orion A and B were compared with J=1-0 of the 12CO, 13CO, and C18O data at the same angular resolution to derive the spatial distributions of the physical properties of the molecular gas (Nishimura et al. 2015). We then explored the large velocity gradient formalism to determine the gas density and temperature using line combinations of 12CO(2-1), 13CO(2-1), and 13CO(1-0). We found that this line combination effectively can solve the density and temperature of the molecular cloud in this size scale, which can be compared with the star formation activity there. These J=2-1 data of the Galactic molecular clouds will be precious for the comparison with those of extra-galactic ones that will be obtained with the ALMA with the comparable spatial resolutions.

  1. Distribution characteristics and source identification of polychlorinated dibenzo-p-dioxin and dibenzofurans, and dioxin-like polychlorinated biphenyls in the waters from River Kanzaki, running through Osaka urban area, Japan.

    PubMed

    Kishida, Masao

    2013-03-01

    This is the first to elucidate the distribution and sources of polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/PCDFs), and dioxin-like polychlorinated biphenyls in the waters from Kanzaki River, which is one of the most heavily polluted rivers in Japan. The World Health Organization (WHO)-toxic equivalent quantities (TEQs) in waters from the mainstream exceeded the Japanese environmental standard (1.0 pg-TEQ/L). The PCDD/PCDFs were dominated by highly chlorinated DFs, which predominantly contributed to the WHO-TEQs, suggesting that the main causes would be the incineration-related wastes. To find the sources, the dioxin congener concentrations in water and sediment samples from its tributary small waterways were determined. Abnormally high WHO-TEQs were detected in a water (50 pg-TEQ/L) and a sediment sample (41,000 ng-TEQ/kg dry weight) near the industrial solid waste incinerators (ISWIs). The PCDD/PCDF characteristics agreed well with those of the incinerator-related wastes as seen in the mainstream. These facts indicate that the dioxin pollution in the mainstream could be largely related to the industrial wastes from the ISWIs. Here, a TEQ apportionment method was used to understand the contribution of the pyrogenic sources to the WHO-TEQs. The average contribution ratios of the pyrogenic sources to WHO-TEQs were more than 80% for river waters from the mainstream, indicating that the elevated WHO-TEQs in the mainstream had been largely caused by the ISWIs.

  2. Knowledge Discovery from Growing Social Networks

    DTIC Science & Technology

    2009-12-24

    University, Aichi, Japan 4motoda@ar.sanken.osaka-u.ac.jp, Osaka Univesity , Osaka, Japan Abstract We address the problem of ranking influential nodes in...rins.ryukoku.ac.jp 3 Department of Integrated Information Technology, Aoyama Gakuin Univesity Kanagawa 229-8558, Japan ohara@it.aoyama.ac.jp 4 Institute...understood, the conventional method is not practical unless we rely on high-performance computers and sophisticated techniques such as parallel computing (see

  3. Observations and Evaluations of a Far East Trip

    DTIC Science & Technology

    1992-12-01

    prestigious universities in Japan. Dr. Hideki Yukawa of Osaka University is the first Japanese physicist who earned the Nobel Prize (in 1949). Also, Osaka...They were also proud of their huge mechanical testing facility. The author’s visit to Nippon Steel was particularly beneficial because Dr. Hideki

  4. Precodings for Transmission Rate Increasing in MIMO Single Carrier Block Transmissions

    DTIC Science & Technology

    2005-01-01

    Engineering, Osaka Prefecture University, Sakai, Osaka, Japan. summary In wireless communication systems, multi- input multi- output ( MIMO ) wireless, which...by the computer simulations. References [1] J. Yang and S. Roy, “On joint transmitter and receiver optimization for multiple - input - multiple - output ...Precodings for Transmission Rate Increasing in MIMO Single Carrier Block Transmissions Shusuke Narieda and Katsumi Yamashita Graduate School of

  5. Developing a Detailed Integrated Optics Computational Model Capable of Quantitative Descriptions and Predictions of the Image Analysis Performance of Compound Eyes

    DTIC Science & Technology

    2006-02-06

    Takaku Y, Horiguchi H, Stavenga DG (2005) The leaf beetle, the jewel beetle, and the damselfly; insects with a multilayered show case. In: Structural ... color in biological systems – principles and applications (Kinoshita S, ed.), pp 153-176. Osaka University Press, Osaka 16. Stavenga DG, Foletti S

  6. 77 FR 1725 - Certain Blu-Ray Disc Players, Components Thereof and Products Containing Same; Notice of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-11

    ...-1 Nakagaito, Daito City, Osaka 574- 0013, Japan. Funai Corporation, Inc., 201 Route 17 North, Suite..., Kadoma-shi, Osaka 571- 8501, Japan. Panasonic Corporation of North America, One Panasonic Way, Seacaucus..., Kawasaki-ku, Kawasaki-shi, Kanagawa 210-8569, Japan. D&M Holdings US, Inc., 100 Corporate Drive, Mahwah, NJ...

  7. A New Direction for International Education.

    ERIC Educational Resources Information Center

    Wiese, James L.

    1992-01-01

    The Osaka International School enrolls students from 22 nationalities in programs from early childhood through a postgraduate year. Osaka Intercultural Academy offers a middle school and a high school program, primarily for Japanese students who have lived overseas. The study of English and Japanese is mandated in both schools. (MLF)

  8. A new ventriculoperitoneal shunt with a telemetric intracranial pressure sensor: clinical experience in 94 patients with hydrocephalus.

    PubMed

    Miyake, H; Ohta, T; Kajimoto, Y; Matsukawa, M

    1997-05-01

    We have developed a telemetric intracranial pressure sensor (OSAKA telesensor; Nagano Keiki Seisakusyo Co. Ltd., Tokyo, Japan) and investigated the clinical usefulness of new ventriculoperitoneal shunting with an OSAKA telesensor, an on-off valve, and a programmable valve. The OSAKA telesensor was applied in 94 patients at Osaka Medical College between March 1986 and December 1995. Postoperative management, postoperative course, postural change of intracranial pressure (ICP), and zero drift of the OSAKA telesensor were investigated. ICP was measured easily in all patients with no inconvenience. The setting of the programmable valve was adjusted postoperatively 38 times in 25 patients. Postoperative ICP in the upright position was -14.9 +/- 4.5 mm Hg, and the difference in ICP between the supine and the upright position was about 20 mm Hg. The slope of the decrease in ICP with continuous postural changes from the supine to the upright position was steep until about 30 to 45 degrees but became incrementally less or even rose slightly about this angle. The initial slope was steeper when the shunt was open than when the shunt was closed; it was also steeper postoperatively than preoperatively. This initial slope, therefore, may indicate the intracranial compliance. Seven cases of shunt malfunction were diagnosed correctly by ICP measurements. Zero drift of the OSAKA telesensor was easily corrected by comparing the ICP reading from the telesensor with the puncture pressure in the on-off valve. The OSAKA telesensor is very useful in the postoperative care and pathophysiological evaluation of patients with hydrocephalus.

  9. PREFACE: Nanospintronics design and realization

    NASA Astrophysics Data System (ADS)

    Akai, Hisazumi; Katayama-Yoshida, Hiroshi; Kasai, Hideaki

    2004-12-01

    This special issue of Journal of Physics: Condensed Matter contains selected papers from the 1st International Conference on Nanospintronics Design and Realization (ICNDR 2004), which was held in Kyoto, Japan, 24--28 May 2004. This conference was organized by the Nanospintronics Design and Realization project members: Hideaki Kasai, Osaka (Chair of the Conference) Hisazumi Akai, Osaka Hajime Asahi, Osaka Wilson Agerico Diño, Osaka Hiroshi Harima, Kyoto Tomoyuki Kakeshita, Osaka Junjiro Kanamori, Kyoto Hiroshi Katayama-Yoshida, Osaka Koichi Kusakabe, Osaka Hiroshi Nakanishi, Osaka (Secretary) Tamio Oguchi, Hiroshima Teruo Ono, Osaka Naoshi Suzuki, Osaka Hitoshi Tabata, Osaka under the auspices of the Japan Ministry of Education, Culture, Sports, Science and Technology (MEXT) Special Coordination Funds for Promoting Science and Technology, and the sponsorship of Osaka University and the International Institute for Advanced Studies (IIAS). The conference is intended to provide an international forum for experimental and theoretical researchers, in the rapidly developing field of nanospintronics. It aims to: provide an overview of our current understanding of the physics of spin transport in (magnetic) semiconductors and hybrid magnetic/semiconductor structures; provide a venue to present and discuss the latest developments in using spin-dependent phenomena in nano-(opto-) electronics and computing applications; provide a venue for discussion and assessment of other possible means of exploiting the spin-dependent phenomena in future nano-(opto-) electronic and computing applications; address current (and foreseeable future) problems, of fundamental and applied nature, in an effort to bridge the physics and technology gap between semiconducting and magnetic materials. All of these being geared towards bringing about the realization of a functioning nanospintronics. A total of 127 delegates from 15 countries took part in ICNDR 2004, which was comprised of 62 invited

  10. 76 FR 66324 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-Advanced Media...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-26

    ...; Panasonic AVC Networks Company, Kadoma City, Osaka, JAPAN; VSN Video Steam Networks, S.L., Barcelona, SPAIN..., Chime Media, Weston, VA; E!Entertainment, Los Angeles, CA; and MAGIX AG, Berlin, GERMANY, have...

  11. Professor Nambu, string theory, and the moonshine phenomenon

    NASA Astrophysics Data System (ADS)

    Eguchi, Tohru

    2016-11-01

    I first recall the last occasion I met the late Professor Yoichiro Nambu, in a hospital in Osaka. I then present a brief introduction to a moonshine phenomenon in string theory that have recently come under investigation.

  12. Views on Inertial Fusion Energy Development (lirpp Vol. 11)

    NASA Astrophysics Data System (ADS)

    Nakai, S.

    2016-10-01

    It is my great honor to receive the Edward Teller Award. Representing the Institute of Laser Engineering, Osaka University, I would like to appreciate your favorite recognition on our achievements in laser fusion research...

  13. 75 FR 66358 - Trade Mission to Mexico in Conjunction With Trade Winds Forum-The Americas

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-28

    ... major industrial area that includes Toluca, Puebla and Queretaro. Mexico City's Federal District... after the greater areas of Tokyo, New York, Los Angeles, Chicago, Paris, London and Osaka/Kobe, and the...

  14. Resampling-Based Gap Analysis for Detecting Nodes with High Centrality on Large Social Network

    DTIC Science & Technology

    2015-05-22

    Hiroshi Motoda4,5 1 Department of Integrated Information Technology, Aoyama Gakuin University, Kanagawa, Japan ohara@it.aoyama.ac.jp 2 School of...Administration and Informatics, University of Shizuoka, Shizuoka, Japan k-saito@u-shizuoka-ken.ac.jp 3 Department of Electronics and Informatics, Ryukoku...University, Shiga, Japan kimura@rins.ryukoku.ac.jp 4 Institute of Scientific and Industrial Research, Osaka University, Osaka, Japan 5 School of

  15. Symposium on Turbulent Shear Flows (3rd), University of California, Davis, California, 9-11 September 1981.

    DTIC Science & Technology

    1981-09-01

    Karlsruhe, WEST GERMANY Prof. S. Corrsin Dr. J.-P. Dussauge Mechs. & Mats. Sci. Dept. IMST The Johns Hopkins Univ. 12 Av. General Leclerc Baltimore , MD...Der Merwe Osaka University 44 Canyon Suita, Osaka, 565 JAPAN Berario, Johannesburg Transvaal, SOUTH AFRICA Dr. K. Takeuchi Owens Corning Fiberglas...steps). The total CPU time on a VAX computer was 27 minutes, at a cost of $16. rSULTS 0.04 The calculations reported in this section were obtained from

  16. Impact of Fast Ignition on Laser Fusion Energy Development

    NASA Astrophysics Data System (ADS)

    Mirna, Kunioki

    2016-10-01

    Reviewed are the early history of Japanese laser fusion research and the recent achievement of fast ignition research at Institute of Laser Engineering (ILE), Osaka University. After the achievement of high density compression at Osaka University, LLE of University Rochester, and LLNL, the critical issue of Inertial Fusion Energy (IFE) research became the formation of hot spark in a compressed plasma. In this lecture, the history of the fast ignition research will be reviewed and future prospects are presented.

  17. The Ballistic and Corrosion Evaluation of Magnesium Elektron E675 vs. Baseline Magnesium Alloy AZ31B and Aluminum Alloy 5083 for Armor Applications

    DTIC Science & Technology

    2011-06-01

    MURMAN S CIMPOERU D PAUL PO BOX 4331 MELBOURNE VIC 3001 AUSTRALIA 1 OSAKA UNIVERSITY JOINING & WELDING RSCH INST K KONDOH 11...UNIV APPLIED RSRCH LAB ACOUSTICS PRGM D SWANSON 504L APPLIED SCI BLDG UNIVERSITY PK PA 16803 1 PACIFIC NORTHWEST NATL LAB E NYBERG...1 MIHOGAOAKA IBARAKI OSAKA 567-0047 JAPAN 1 DEFENSE RESEARCH AGENCY B JAMES PORTON DOWN SALISBURY WTTTS SP04 OJQ UNITED KINGDOM

  18. Subsurface geology of Kansai International Airport: sequence related to global glacial - interglacial cycles and island tectonics

    NASA Astrophysics Data System (ADS)

    Takemura, K.; Kitada, N.; Furudoi, T.; Nakaseko, K.

    2007-12-01

    Tectonic sedimentary basins aligned in the central part of Japan during Quaternary . Thick sediments deposited in these basins provide useful records of climatic changes and tectonics throughout Quaternary. The Osaka sedimentary basin including Osaka Bay and area of Kansai International Airport is one of them. The Quaternary Osaka sedimentary basin has developed at an eastern contractional bend of a major transcurrent fault system named the Median Tectonic Line, which divides the southwest Japan arc. The thickness of Pliocene - Pleistocene sediments reaches to ca 3500m at the deepest part. These sequences are called the Osaka Group and are distributed in the Osaka Bay and exposed in the surrounding mountain areas. The Osaka Group is characterized by alternating sequences of marine and nonmarine strata. The subsurface sediments of Kansai International Airport (KIA) is composed mainly of Pliocene - Pleistocene sediments, which is characterized by alternating sequences of marine and nonmarine strata related to glacial - interglacial cycles. . The stratigraphy at KIA was established by micropaleontological, tephrochronological and magnetostratigraphical method. The sedimentary sequence at KIX is divided into two main units (Kukojima and Sennanoki Formations in ascending order) with the uncomformity within two units. Although thick marine clay units are mainly of the subsurface sequence, characteristics of coarser sediment units have an important role of moving of water during construction of the reclaimed land.

  19. Regional and local variations in atmospheric aerosols using ground-based sun photometry during Distributed Regional Aerosol Gridded Observation Networks (DRAGON) in 2012

    NASA Astrophysics Data System (ADS)

    Sano, Itaru; Mukai, Sonoyo; Nakata, Makiko; Holben, Brent N.

    2016-11-01

    Aerosol mass concentrations are affected by local emissions as well as long-range transboundary (LRT) aerosols. This work investigates regional and local variations of aerosols based on Distributed Regional Aerosol Gridded Observation Networks (DRAGON). We constructed DRAGON-Japan and DRAGON-Osaka in spring of 2012. The former network covers almost all of Japan in order to obtain aerosol information in regional scale over Japanese islands. It was determined from the DRAGON-Japan campaign that the values of aerosol optical thickness (AOT) decrease from west to east during an aerosol episode. In fact, the highest AOT was recorded at Fukue Island at the western end of the network, and the value was much higher than that of urban areas. The latter network (DRAGON-Osaka) was set as a dense instrument network in the megalopolis of Osaka, with a population of 12 million, to better understand local aerosol dynamics in urban areas. AOT was further measured with a mobile sun photometer attached to a car. This transect information showed that aerosol concentrations rapidly changed in time and space together when most of the Osaka area was covered with moderate LRT aerosols. The combined use of the dense instrument network (DRAGON-Osaka) and high-frequency measurements provides the motion of aerosol advection, which coincides with the wind vector around the layer between 700 and 850 hPa as provided by the reanalysis data of the National Centers for Environmental Prediction (NCEP).

  20. Regional and Local Variations in Atmospheric Aerosols Using Ground-Based Sun Photometry During Distributed Regional Aerosol Gridded Observation Networks (DRAGON) in 2012

    NASA Technical Reports Server (NTRS)

    Sano, Itaru; Mukai, Sonoyo; Nakata, Makiko; Holben, Brent N.

    2016-01-01

    Aerosol mass concentrations are affected by local emissions as well as long-range transboundary (LRT) aerosols. This work investigates regional and local variations of aerosols based on Distributed Regional Aerosol Gridded Observation Networks (DRAGON).We constructed DRAGON-Japan and DRAGON-Osaka in spring of 2012. The former network covers almost all of Japan in order to obtain aerosol information in regional scale over Japanese islands. It was determined from the DRAGON-Japan campaign that the values of aerosol optical thickness (AOT) decrease from west to east during an aerosol episode. In fact, the highest AOT was recorded at Fukue Island at the western end of the network, and the value was much higher than that of urban areas. The latter network (DRAGON-Osaka) was set as a dense instrument network in the megalopolis of Osaka, with a population of 12 million, to better understand local aerosol dynamics in urban areas. AOT was further measured with a mobile sun photometer attached to a car. This transect information showed that aerosol concentrations rapidly changed in time and space together when most of the Osaka area was covered with moderate LRT aerosols. The combined use of the dense instrument network (DRAGON-Osaka) and high-frequency measurements provides the motion of aerosol advection, which coincides with the wind vector around the layer between 700 and 850 hPa as provided by the reanalysis data of the National Centers for Environmental Prediction (NCEP).

  1. [Review of the pharmaceutical exhibitions in the Meiji Era (Supplement)].

    PubMed

    Koyama, T

    1994-01-01

    The author described (Jpn. J. History Pharm. 16(1), 9-20 (1981) the Review of the Pharmaceutical Exhibitions in the Meiji era. But afterwards the author found there were omissions of three exhibitions. These are the Nagaoka, the Osaka, and the Akita Exhibitions. The Nagaoka Exhibition was organized by the Nagaoka Pharmacists Association in June, 1890. The Osaka Exhibition opened on Jan. 18, 1891 by Osaka Branch of the Pharmaceutical Society of Japan. The Akita Pharmaceutical Exhibition was held on Sept. 24-26, 1892, as the chief event of the opening ceremony of the Akita Drug-Trader Association, united pharmacists, druggists, and drug-manufacturers throughout Akita Prefecture. It is the most large-scaled of the three. The exhibits were 1,419, and the visitors were above 8,830. The planning originated with a young pharmacist Masayasu Hanyu.

  2. Relationship between dietary exposure and serum perfluorochemical (PFC) levels--a case study.

    PubMed

    Kärrman, Anna; Harada, Kouji H; Inoue, Kayoko; Takasuga, Takumi; Ohi, Etsumasa; Koizumi, Akio

    2009-05-01

    Daily dietary intake of perfluorinated chemicals (PFCs) in relation to serum levels was assessed by determination of nine PFCs including perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) in matched daily diet duplicates and serum samples. Diet and serum were collected in year 2004 from 20 women in Osaka and Miyagi, Japan. Only PFOS and PFOA were detected in the diet samples and no significant difference between cities was seen. After adjusted by water content, diet concentration of PFOA was significantly higher in Osaka. The median daily intake calculated using the measured diet concentrations was 1.47 ng PFOS/kg b.w. and 1.28 ng PFOA/kg b.w. for Osaka, and 1.08 ng PFOS/kg b.w. and 0.72 ng PFOA/kg b.w. for Miyagi. A significant difference between cities was seen for the serum concentrations with median of 31 ng/mL PFOS and PFOA in Osaka, compared to 14 ng/mL PFOS and 4.6 ng/mL PFOA in Miyagi. Carboxylates such as perfluorononanoic acid (PFNA) and perfluoroundecanoic acid (PFUnDA) were also detected in serum at median levels 6.9 ng/mL and 3.2 ng/mL (Osaka), and 2.8 ng/mL and 5.1 ng/mL (Miyagi). Based on one-compartment model under steady state, dietary intake of PFOS and PFOA accounted for only 22.4% and 23.7% of serum levels in Osaka females, and in contrast 92.5% and 110.6% in Miyagi females, respectively.

  3. Paleo-stress and temperatures based on calcite twin and vitrinite reflectance in the Nojima Fault, SW Japan

    NASA Astrophysics Data System (ADS)

    Oosono, N.; Furuta, K.; Sakaguchi, A.

    2016-12-01

    The seismogenic fault must experience rupture propagation and frictional slip during earthquakes. The record of this process can be estimated from heat and stress records at principal shear zone of fault. In recent, some methods were developed to detect heat and stress from fault rocks. The organic materials in sediment are delicate with heating to be sensitive geo-thermometer. The vitrinite reflectance and Raman spectra analysis were applied for detection of fault heating. The mechanical twin of calcite depends on shear stress, and twin density method is proposed to estimate paleo-stress for fault rock in brittle regime. The Nojima Fault develops at Awaji Island SW Japan is the seismogenic fault of the 1995 Kobe earthquake. The Nojima Fault strikes northeast - south west and bounds Ryoke Granite and Pleistocene Osaka Groups. The Ryoke Granite thrusts up the Osaka Group and suffers deformation more than several ten meters. This damage zone is characterized by brittle failure, and some cracks are filled with fine calcite minerals. The Osaka Group is composed of a sandstone and silt layers, and contacts with Ryoke Granite at silt layer. The fault related folds are observed around the fault zone, and some granite blokes are scattered within the Osaka Group . In micro structure, possible principal shear zone of narrow dark seem of 5 mm in thickness is developed within the silt layer of the Osaka Group. Some coal laminas are included in the Osaka Group, and the vitrinite reflectance was approximately 0.2%. The estimated paleo-temperature of the host rock is approximately several ten degrees. Such low temperature of the sediment must be obtained shallow burial depth, and the sediment may record recent fault activity. Low temperature host rock can detect small signal of frictional heat.

  4. Development of metrology for one-meter-long mirrors (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Aono, Shinya; Nakamori, Hiroki; Ueda, Akihiko; Tsumra, Takashi; Okada, Hiromi

    2016-09-01

    We fabricate ultra-precision mirrors, Osaka Mirror, for synchrotron facilities. In order to fabricate them, it is very important to measure mirror surface precisely. In respect of the importance, we use two kinds of metrology, RADSI and MSI, developed by Osaka University. We have delivered more than 300 mirrors to synchrotron facilities all over the world since 2006 and our mirrors have produced excellent results to many researchers. As the demand on one meter long mirrors has increased lately, we developed RADSI and MSI systems which are capable in precise measurement of such long mirrors.

  5. Development of magnetically levitated high speed transport system in Japan

    SciTech Connect

    Sawada, Kazuo

    1996-07-01

    In Japan, huge passenger traffic moves through the Tokyo-Osaka corridor and the demand is mounting on one more high speed line besides the Tokaido Shinkansen. A magnetically levitated vehicle (JR Maglev) using superconducting magnets has been developed for the Tokyo-Osaka superspeed express. JR Maglev has many advantages over conventional rail systems. This paper describes the necessity of one more high speed line in this corridor, the reason the author chose Maglev, the scheme of this system, history of the development and outline of the new Yamanashi test line project.

  6. Importance of Interaction between Integrin and Actin Cytoskeleton in Suspension Adaptation of CHO cells.

    PubMed

    Walther, Christa G; Whitfield, Robert; James, David C

    2016-04-01

    The biopharmaceutical production process relies upon mammalian cell technology where single cells proliferate in suspension in a chemically defined synthetic environment. This environment lacks exogenous growth factors, usually contributing to proliferation of fibroblastic cell types such as Chinese hamster ovary (CHO) cells. Use of CHO cells for production hence requires a lengthy 'adaptation' process to select clones capable of proliferation as single cells in suspension. The underlying molecular changes permitting proliferation in suspension are not known. Comparison of the non-suspension-adapted clone CHO-AD and a suspension-adapted propriety cell line CHO-SA by flow cytometric analysis revealed a highly variable bi-modal expression pattern for cell-to-cell contact proteins in contrast to the expression pattern seen for integrins. Those have a uni-modal expression on suspension and adherent cells. Integrins showed a conformation distinguished by regularly distributed clusters forming a sphere on the cell membrane of suspension-adapted cells. Actin cytoskeleton analysis revealed reorganisation from the typical fibrillar morphology found in adherent cells to an enforced spherical subcortical actin sheath in suspension cells. The uni-modal expression and specific clustering of integrins could be confirmed for CHO-S, another suspension cell line. Cytochalasin D treatment resulted in breakdown of the actin sheath and the sphere-like integrin conformation demonstrating the link between integrins and actin in suspension-adapted CHO cells. The data demonstrates the importance of signalling changes, leading to an integrin rearrangement on the cell surface, and the necessity of the reinforcement of the actin cytoskeleton for proliferation in suspension conditions.

  7. Association between Lifestyle and School Attendance in Japanese Medical Students: A Pilot Study

    ERIC Educational Resources Information Center

    Tanaka, Masaaki; Watanabe, Yasuyoshi

    2012-01-01

    Objective: Lifestyle factors are thought to be associated with students' academic performance. Whether lifestyle factors were associated with medical students' school attendance was determined. Design: Cross-sectional design. Setting: The study group consisted of 157 healthy second-year medical students attending Osaka City University Graduate…

  8. Σ MRL Multidisciplinary Research Laboratory System for Future Development-An International Student Network-

    NASA Astrophysics Data System (ADS)

    Itoh, Tadashi

    The Graduate School of Engineering Science, Osaka University started in 2002 the project of “An International Student Network” on Multidisciplinary Research Laboratory System for Future Development. The concept, system and activity for encouraging students to create their international human-relation network for young researchers and engineers are described. Some typical activities are introduced in detail.

  9. Total cholesterol performance of Abell–Levy–Brodie–Kendall reference measurement procedure: Certification of Japanese in-vitro diagnostic assay manufacturers through CDC’s Cholesterol Reference Method Laboratory Network☆

    PubMed Central

    Nakamura, Masakazu; Iso, Hiroyasu; Kitamura, Akihiko; Imano, Hironori; Kiyama, Masahiko; Yokoyama, Shinji; Kayamori, Yuzo; Koyama, Isao; Nishimura, Kunihiro; Nakai, Michikazu; Dasti, Mahnaz; Vesper, Hubert W.; Teramoto, Tamio; Miyamoto, Yoshihiro

    2015-01-01

    Background Accurate measurement of total cholesterol (TC) is important for cardiovascular disease risk management. The US Centers for Disease Control and Prevention (CDC) and Cholesterol Reference Method Laboratory Network (CRMLN) perform Abell–Levy–Brodie–Kendall (AK) reference measurement procedure (RMP) for TC as a secondary reference method, and implement Certification Protocol for Manufacturers. Japanese CRMLN laboratory at Osaka performed the AK RMP for 22 years, and conducted TC certification for reagent/calibrator/instrument systems of six Japanese manufacturers every 2 years for 16 years. Osaka TC performance was examined and compared to CDC’s reference values. Methods AK RMP involved sample hydrolysis, cholesterol extraction, and determination of cholesterol levels by spectrophotometry. The Certification Protocol for Manufacturers includes comparison with AK RMP using at least 40 fresh specimens. Demonstration of average bias ≤3% and total coefficient of variation ≤3% qualified an analytical system for certification. Results In the AK RMP used in the Osaka CRMLN laboratory, the regression equation for measuring TC was y (Osaka) = 1.000x (CDC) + 0.032 (n = 619, R2 = 1.000). Six Japanese manufacturers had allowable performance for certification. Conclusions The AK RMP for TC measurement was accurate, precise, and stable for 22 years. Six Japanese manufacturers were certified for 16 years. PMID:25818239

  10. Editorial

    NASA Astrophysics Data System (ADS)

    Ueda, Yoshio; Asakura, Nobuyuki; Hoshino, Kazuo; Ito, Atsushi; Kajita, Shin; Kobayashi, Masahiro; Lee, Heun Tae; Nakano, Tomohide; Tokitani, Masayuki

    2015-08-01

    The 21st International Conference on Plasma-Surface Interactions in Controlled Fusion Devices (PSI-21) was held in Kanazawa, Ishikawa prefecture, Japan from the 26th to the 30th of May 2014. This conference was hosted by National Institute for Fusion Science and supported by Nagoya University, Kanazawa University, Osaka University and Japan Atomic Energy Agency.

  11. Emerging Issues in Educational Reform in Japan.

    ERIC Educational Resources Information Center

    Wong, Kenneth K.

    2003-01-01

    Uses the demand-supply continuum to look at emerging reforms in the Japanese educational system. Data from fieldwork in major urban districts and their prefectures in Nagoya, Osaka, and Tokyo highlight demand-driven reform (higher education restructuring), integrated governance (mediating demand and supply at the K-12 levels), and ongoing…

  12. COMET and PRISM - Search for Charged Lepton Flavor Violation with Muons

    NASA Astrophysics Data System (ADS)

    Kuno, Yoshitaka

    2012-04-01

    The experiment (COMET) at J-PARC to search for a charged-lepton-flavor-violating process of muon to electron conversion in a muonic atom is described. Future prospects of an experiment (PRISM) with even higher sensitivity is mentioned. On-going R&D on a highly intense muon source (MuSIC) at Osaka University is presented.

  13. Hemlock woolly adelgid phenology and predacious beetle community on Japanese hemlocks

    Treesearch

    Shigehiko Shiyake; Yorio Miyatake; Michael Montgomery; Ashley. Lamb

    2008-01-01

    Monthly samples of the hemlock woolly adelgid (HWA), Adelges tsugae, and predatory beetles were taken from Tsuga sieboldii near the border of Osaka and Kyoto prefectures. The beetles were collected by sweeping the canopy up to 5 meters height with nets. The phenology of HWA life stages were monitored by collecting branches and...

  14. Microbial control of Asian longhorned beetles - what are fungal bands?

    Treesearch

    Ann E. Hajek; Thomas Dubois; Jennifer Lund; Ryan Shanley; Leah Bauer; Michael Smith; Peng Fan; Huang Bo; Hu Jiafu; Zengzhi Li

    2007-01-01

    In Japan, the entomopathogenic fungus Beauveria brongniartii is grown in nonwoven fiber bands that are placed around trunks of orchard trees for control of numerous cerambycid pests, including Anoplophora chinensis (= A. malasiaca). The Japanese company producing bands, Nitto Denko in Osaka, markets bands...

  15. 78 FR 57882 - Certain Tires and Products Containing Same; Institution of Investigation Pursuant to United...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-20

    ... 337 of the Tariff Act of 1930, as amended, 19 U.S.C. 1337, on behalf of Toyo Tire & Rubber Co., Ltd... complainants are: Toyo Tire & Rubber Co., Ltd., 1-17-18 Edobori, Nishi-ku, Osaka 550- 8661, Japan Toyo Tire... Rubber & Plastic Co., Ltd., The West of JinGuang Street, Chenming Industrial Park, Shouguang...

  16. Long term operation of the 100-cm{sup 2} class single cell of MCFC

    SciTech Connect

    Tanimoto, Kazumi; Yanagida, Masahiro; Kojima, Toshikatsu

    1996-12-31

    The R&D on Molten Carbonate Fuel Cell (MCFC) is proceeding as one of the New Sun Shine Project sponsored by Japanese government. In ONRI (Osaka National Research Institute), the tested MCFCs were assembled with the state-of-the-art components and operated under the load condition for 40000 hours and 34000 hours. We analyzed the performance reduction.

  17. Total cholesterol performance of Abell-Levy-Brodie-Kendall reference measurement procedure: Certification of Japanese in-vitro diagnostic assay manufacturers through CDC's Cholesterol Reference Method Laboratory Network.

    PubMed

    Nakamura, Masakazu; Iso, Hiroyasu; Kitamura, Akihiko; Imano, Hironori; Kiyama, Masahiko; Yokoyama, Shinji; Kayamori, Yuzo; Koyama, Isao; Nishimura, Kunihiro; Nakai, Michikazu; Dasti, Mahnaz; Vesper, Hubert W; Teramoto, Tamio; Miyamoto, Yoshihiro

    2015-05-20

    Accurate measurement of total cholesterol (TC) is important for cardiovascular disease risk management. The US Centers for Disease Control and Prevention (CDC) and Cholesterol Reference Method Laboratory Network (CRMLN) perform Abell-Levy-Brodie-Kendall (AK) reference measurement procedure (RMP) for TC as a secondary reference method, and implement Certification Protocol for Manufacturers. Japanese CRMLN laboratory at Osaka performed the AK RMP for 22 years, and conducted TC certification for reagent/calibrator/instrument systems of six Japanese manufacturers every 2 years for 16 years. Osaka TC performance was examined and compared to CDC's reference values. AK RMP involved sample hydrolysis, cholesterol extraction, and determination of cholesterol levels by spectrophotometry. The Certification Protocol for Manufacturers includes comparison with AK RMP using at least 40 fresh specimens. Demonstration of average bias ≤3% and total coefficient of variation ≤3% qualified an analytical system for certification. In the AK RMP used in the Osaka CRMLN laboratory, the regression equation for measuring TC was y (Osaka)=1.000x (CDC)+0.032 (n=619, R(2)=1.000). Six Japanese manufacturers had allowable performance for certification. The AK RMP for TC measurement was accurate, precise, and stable for 22 years. Six Japanese manufacturers were certified for 16 years. Copyright © 2015 Elsevier B.V. All rights reserved.

  18. BioMagResBank.

    PubMed

    Ulrich, Eldon L; Akutsu, Hideo; Doreleijers, Jurgen F; Harano, Yoko; Ioannidis, Yannis E; Lin, Jundong; Livny, Miron; Mading, Steve; Maziuk, Dimitri; Miller, Zachary; Nakatani, Eiichi; Schulte, Christopher F; Tolmie, David E; Kent Wenger, R; Yao, Hongyang; Markley, John L

    2008-01-01

    The BioMagResBank (BMRB: www.bmrb.wisc.edu) is a repository for experimental and derived data gathered from nuclear magnetic resonance (NMR) spectroscopic studies of biological molecules. BMRB is a partner in the Worldwide Protein Data Bank (wwPDB). The BMRB archive consists of four main data depositories: (i) quantitative NMR spectral parameters for proteins, peptides, nucleic acids, carbohydrates and ligands or cofactors (assigned chemical shifts, coupling constants and peak lists) and derived data (relaxation parameters, residual dipolar couplings, hydrogen exchange rates, pK(a) values, etc.), (ii) databases for NMR restraints processed from original author depositions available from the Protein Data Bank, (iii) time-domain (raw) spectral data from NMR experiments used to assign spectral resonances and determine the structures of biological macromolecules and (iv) a database of one- and two-dimensional (1)H and (13)C one- and two-dimensional NMR spectra for over 250 metabolites. The BMRB website provides free access to all of these data. BMRB has tools for querying the archive and retrieving information and an ftp site (ftp.bmrb.wisc.edu) where data in the archive can be downloaded in bulk. Two BMRB mirror sites exist: one at the PDBj, Protein Research Institute, Osaka University, Osaka, Japan (bmrb.protein.osaka-u.ac.jp) and the other at CERM, University of Florence, Florence, Italy (bmrb.postgenomicnmr.net/). The site at Osaka also accepts and processes data depositions.

  19. Cross-contamination of cell lines as revealed by DNA fingerprinting in the IFO animal cell bank.

    PubMed

    Satoh, M; Takeuchi, M

    1993-01-01

    For quality control of cell lines, the Institute for Fermentation, Osaka (IFO) animal cell bank recently introduced DNA fingerprinting analysis, which enables verification of cell lines at the individual level, to detect cross-culture contamination. By using this analysis, we found two cases of cross-contamination of cell lines.

  20. The Effects of Marital Support, Social Network Support, and Parenting Stress on Parenting: Self-Efficacy among Mothers of Young Children in Japan

    ERIC Educational Resources Information Center

    Suzuki, Sawako

    2010-01-01

    This study investigated whether Japanese women's perceived marital and social support affect their parenting self-efficacy directly or indirectly through their levels of parenting stress. Participants were 98 mothers of children in the second grade living in Sapporo or Osaka, Japan. Data collected through surveys were submitted to a structural…

  1. Increasing the Number of African American Students in Undergraduate Level Classes of Chinese: A Call to Action

    ERIC Educational Resources Information Center

    Li, Huiwen

    2015-01-01

    Chinese language is the only ideographic language remaining in the world (Osaka, 1976). It conveys affluent Chinese culture and has great influences on the East Asian countries (Miyake, 2013). In the economic globalization of the world, China's economy and international influence are expanding. For these reasons and many more the Chinese language…

  2. BioMagResBank

    PubMed Central

    Ulrich, Eldon L.; Akutsu, Hideo; Doreleijers, Jurgen F.; Harano, Yoko; Ioannidis, Yannis E.; Lin, Jundong; Livny, Miron; Mading, Steve; Maziuk, Dimitri; Miller, Zachary; Nakatani, Eiichi; Schulte, Christopher F.; Tolmie, David E.; Kent Wenger, R.; Yao, Hongyang; Markley, John L.

    2008-01-01

    The BioMagResBank (BMRB: www.bmrb.wisc.edu) is a repository for experimental and derived data gathered from nuclear magnetic resonance (NMR) spectroscopic studies of biological molecules. BMRB is a partner in the Worldwide Protein Data Bank (wwPDB). The BMRB archive consists of four main data depositories: (i) quantitative NMR spectral parameters for proteins, peptides, nucleic acids, carbohydrates and ligands or cofactors (assigned chemical shifts, coupling constants and peak lists) and derived data (relaxation parameters, residual dipolar couplings, hydrogen exchange rates, pKa values, etc.), (ii) databases for NMR restraints processed from original author depositions available from the Protein Data Bank, (iii) time-domain (raw) spectral data from NMR experiments used to assign spectral resonances and determine the structures of biological macromolecules and (iv) a database of one- and two-dimensional 1H and 13C one- and two-dimensional NMR spectra for over 250 metabolites. The BMRB website provides free access to all of these data. BMRB has tools for querying the archive and retrieving information and an ftp site (ftp.bmrb.wisc.edu) where data in the archive can be downloaded in bulk. Two BMRB mirror sites exist: one at the PDBj, Protein Research Institute, Osaka University, Osaka, Japan (bmrb.protein.osaka-u.ac.jp) and the other at CERM, University of Florence, Florence, Italy (bmrb.postgenomicnmr.net/). The site at Osaka also accepts and processes data depositions. PMID:17984079

  3. Research on the Multiple-Choice Test Item in Japan: Toward the Validation of Mathematical Models.

    DTIC Science & Technology

    1980-04-01

    Director, Miss Eunice Mohri , and other ONR/Tokyo staff members for providing me with office space and services, taking me to JICST, and helping me in...12-1 Ohokayama, Meguro-ku Tokyo 152, Japan Dr. Hideo Fujiwara Phone: (06) 877-5111 DepartmenL of Electronic Engineering Faculty of Engineering Osaka

  4. Perception of the Impact of International Education: Japanese vs. American Students.

    ERIC Educational Resources Information Center

    Archwamety, Teara

    This study of Japanese and American exchange students focuses on the "perceived" rather than on the "real" impact of international education on one's own society and on the society hosting the foreign student. Thirty-four randomly selected American undergraduate students attending a Japanese university in Osaka, Japan and 34…

  5. 78 FR 55096 - Certain Point-to-Point Network Communication Devices and Products Containing Same; Institution of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-09

    ... Corporation, 1006, Oaza Kadoma, Kadoma-shi, Osaka, 571-8501, Japan. Panasonic Corporation of North America..., 157-721, Republic of Korea. LG Electronics U.S.A., Inc., 1000 Sylvan Avenue, Englewood Cliffs, NJ..., Japan. Sharp Electronics Corporation, 1 Sharp Plaza, Mahwah, NJ 07495. Sony Computer Entertainment, Inc...

  6. Ballistic Characterization of the Scalability of Magnesium Alloy AMX602

    DTIC Science & Technology

    2015-07-01

    Magnesium Alloy AMX602 by Tyrone L Jones Weapons and Materials Research Directorate, ARL Katsuyoshi Kondoh Joining and Welding Research...formed a collaborative partnership with Osaka University Joining and Welding Research Institute (JWRI), Taber Extrusions, Epson Atmix, Pacific Sowa...alloy are provided. 15. SUBJECT TERMS magnesium, AMX602, armor mechanisms, AZ31B, aluminum alloy 5083 16. SECURITY CLASSIFICATION OF: 17. LIMITATION

  7. SPring-8 BL44XU, beamline designed for structure analysis of large biological macromolecular assemblies

    SciTech Connect

    Higashiura, Akifumi Yamashita, Eiki; Yoshimura, Masato; Hasegawa, Kazuya; Furukawa, Yukito; Kumasaka, Takashi; Tsukihara, Tomitake; Nakagawa, Atsushi

    2016-07-27

    Beamline BL44XU at SPring-8 is operated by the Institute for Protein Research of Osaka University. The beamline is designed for X-ray crystallography of large biological macromolecular assemblies. Here we show its detailed performances, results, and the ongoing upgrade plans.

  8. Hemoglobin M Disease as a Cause of Cyanosis in a Newborn.

    PubMed

    Alonso-Ojembarrena, Almudena; Lubián-López, Simón P

    2016-04-01

    Methemoglobinemia, including the inherited or congenital form, is a known but infrequent cause of neonatal cyanosis. We present the case of a newborn patient with neonatal cyanosis, who was diagnosed with F-M-Osaka methemoglobinemia, and an up-to-date literature review of the disease.

  9. Polarization of Physics on Global Courses

    ERIC Educational Resources Information Center

    Alinea, Allan L.; Naylor, Wade

    2015-01-01

    Since October 2010, the Chemistry-Biology Combined Major Program, an international course taught in English at Osaka University, has been teaching small classes (no more than 20 in size). We present data from the Force Concept Inventory (FCI) given to first-year classical mechanics students (N = 47 students over three years) pre and post score,…

  10. School Uniforms, Routine Activities, and the Social Control of Delinquency in Japan.

    ERIC Educational Resources Information Center

    Tanioka, Ichiro; Glaser, Daniel

    1991-01-01

    Unofficial rates of delinquency (RDs) were studied in Japan for a representative population sample of 1,121 high school students in the Osaka prefecture, mostly from private schools. RD correlations and interpretations were compared with those of similar U.S. studies. Reasons self-reported delinquency in Japan was much lower are discussed. (SLD)

  11. Written Tests of Pronunciation: Do They Work?

    ERIC Educational Resources Information Center

    Buck, Gary

    1989-01-01

    Examination of the reliability and validity of paper-and-pencil pronunciation tests of English as a second language in Osaka (Japan) showed very low reliability. Correlations with more direct measures of pronunciation showed very low validity of written pronunciation tests. Sample tests are appended. (Author/CB)

  12. English Loanwords in the 1990's in Japan.

    ERIC Educational Resources Information Center

    Nakagawa, Akira

    A sociolinguistic analysis of English loan words in use in the 1990s in the discourse of young Japanese people is presented. The study drew data from a 1993 survey of undergraduate students at two Osaka (Japan) higher education institutions, one for men and one for women, which asked what loanwords students used and heard often. The report first…

  13. Local Public Finance in Japan; Urban Affairs Paper No. 3.

    ERIC Educational Resources Information Center

    Hicks, Ursula

    The three largest cities in Japan--Tokyo, Osaka and Nagoya--are used to examine the financial situation of Japanese urban areas. The 1949 Shoup Mission findings and recommendations are reviewed. Demographic data and information on the administrative and the fiscal organization of Japanese cities during the past three decades are presented. Details…

  14. Spectroscopy of Pionic Atoms in the (p,2He) Reaction at RCNP

    NASA Astrophysics Data System (ADS)

    Fujioka, Hiroyuki

    We plan to investigate the formation spectrum of deeply-bound pionic atoms by means of the (p,2He) reaction on 208Pb at RCNP, Osaka University. The experimental setup with a high-resolution spectrometer "GrandRaiden", improved from a past experiment in 1990s using the same reaction, will enable us to achieve a high energy-resolution.

  15. Air Structures: Inflatable Alternatives

    ERIC Educational Resources Information Center

    Valerio, Joseph M.; And Others

    1973-01-01

    Describes and evaluates several avant garde'' examples of air structures. Included are a soft'' child's playpen, a pneudome that employs a water ballast for anchoring, a one-acre enclosed campus, an instant city'' constructed for an industrial design conference, and the Fuji Pavilion, at Expo '70 in Osaka, Japan, that was large enough to cover…

  16. Video im Anfaengerunterricht. Modell: Vorgabe und Einuebung von Dialogsituationen und Sprechintentionen (Video in Teaching Beginners. Model: Example and Practice in Dialog Situations and Topics for Oral Practice)

    ERIC Educational Resources Information Center

    Bauer, Hans L.

    1977-01-01

    Describes the production, at the Goethe Institute in Osaka, of video programs for teaching beginners in German. Learning goals, actualization, sample topics and variation scenes are presented; the teaching process (in ten points) is discussed, theoretically and on the basis of experience. (Text is in German.) (IFS/WGA)

  17. Early Detection and Early Intervention for Children with Developmental Disability, and the Co-operation among Facilities Concerned in Japan.

    ERIC Educational Resources Information Center

    Irie, Norio

    This report studied the cases of 826 infants and toddlers with developmental disabilities from 1988 to 1995 and the role of the facilities in identifying and referring the children to a rehabilitation center in Higashi-Osaka City, Japan. A list of the classification of main developmental disabilities is provided, along with a table showing the…

  18. On the Passage of a Shock Wave Through a Dusty-Gas Layer,

    DTIC Science & Technology

    1982-01-01

    0082-5255 Acknowledgements One of us (H. Miura) is grateful to the University of Osaka Prefecture, Sakai, Japan, for making possible his leave at...3303, the U.S. Army Research Office, and the Defence Research Establishment, Suffield, is acknowledged with thanks. e ".5 9tu or-&TIS :11Ctrjbut 10l

  19. The Effects of Marital Support, Social Network Support, and Parenting Stress on Parenting: Self-Efficacy among Mothers of Young Children in Japan

    ERIC Educational Resources Information Center

    Suzuki, Sawako

    2010-01-01

    This study investigated whether Japanese women's perceived marital and social support affect their parenting self-efficacy directly or indirectly through their levels of parenting stress. Participants were 98 mothers of children in the second grade living in Sapporo or Osaka, Japan. Data collected through surveys were submitted to a structural…

  20. Increasing the Number of African American Students in Undergraduate Level Classes of Chinese: A Call to Action

    ERIC Educational Resources Information Center

    Li, Huiwen

    2015-01-01

    Chinese language is the only ideographic language remaining in the world (Osaka, 1976). It conveys affluent Chinese culture and has great influences on the East Asian countries (Miyake, 2013). In the economic globalization of the world, China's economy and international influence are expanding. For these reasons and many more the Chinese language…

  1. Polarization of Physics on Global Courses

    ERIC Educational Resources Information Center

    Alinea, Allan L.; Naylor, Wade

    2015-01-01

    Since October 2010, the Chemistry-Biology Combined Major Program, an international course taught in English at Osaka University, has been teaching small classes (no more than 20 in size). We present data from the Force Concept Inventory (FCI) given to first-year classical mechanics students (N = 47 students over three years) pre and post score,…

  2. Association between Lifestyle and School Attendance in Japanese Medical Students: A Pilot Study

    ERIC Educational Resources Information Center

    Tanaka, Masaaki; Watanabe, Yasuyoshi

    2012-01-01

    Objective: Lifestyle factors are thought to be associated with students' academic performance. Whether lifestyle factors were associated with medical students' school attendance was determined. Design: Cross-sectional design. Setting: The study group consisted of 157 healthy second-year medical students attending Osaka City University Graduate…

  3. Spatial and temporal variation of atmospheric particle in local scale

    NASA Astrophysics Data System (ADS)

    Mukai, S.; Nakata, M.; Sano, I.; Nakano, T.; Okuhara, T.

    2011-12-01

    This work intends to demonstrate the spatial and temporal variation of atmospheric particles around AERONET/Osaka site. Osaka is the second big city in Japan and a typical Asian urban area. It is well known that the aerosol distribution in Asia is complicated due to the increasing emissions of anthropogenic aerosols in association with economic growth and in addition behavior of natural dusts significantly varies with the seasons. Therefore local spatially and temporally resolved measurements of atmospheric particles in Asian urban city are meaningful. The sampling of PM2.5, PM10 and OBC have been undertaken using an Kimoto/SPM sampler at the AERONET/Osaka site since 2004. It is noted that a portable multi-spectral sun-photometer (Solar-Light Company Microtops-II) has been employed since 2010. It is found from the simultaneous measurements of AOT (aerosol optical thickness) at AERONET/Osaka site and several locations in the neighborhood and PM sampling that the local scale spatial and temporal factors influence the characterization of atmospheric particles for sure and vice versa.

  4. Deletion of tumor progression locus 2 attenuates alcohol induced hepatic inflammation

    USDA-ARS?s Scientific Manuscript database

    BACKGROUND: The pathogenesis of alcoholic liver disease (ALD) involves the interaction of several inflammatory signaling pathways. Tumor progression locus 2 (TPL2), also known as Cancer Osaka Thyroid (COT) and MAP3K8, is a serine threonine kinase that functions as a critical regulator of inflammator...

  5. Boundary migration and disappearance of voids in Alpha-Al2O3 at 2000 deg C

    NASA Technical Reports Server (NTRS)

    Komatsu, M.; Fujita, H.

    1984-01-01

    A series of photographs taken with Osaka University's high temperature 3MV electron microscope of alpha-A1(z)O(3) at 2000 C is presented. The dynamic study shows grain boundary migration in progress and demonstrates that disappearance of voids is controlled by boundary migration.

  6. Reconstruction of the thermal environment evolution from subsurface temperature distribution in Japan and Thailand

    NASA Astrophysics Data System (ADS)

    Hamamoto, H.; Yamano, M.; Goto, S.; Hachinohe, S.; Shiraishi, H.; Ishiyama, T.; Miyakoshi, A.; Taniguchi, M.; Arimoto, H.; Kitaoka, K.

    2012-12-01

    Temperature changes at the ground surface propagate into the underground and disturb the subsurface temperature structure. Analyzing disturbances in the subsurface temperature structure, we can reconstruct the past ground surface temperature (GST) change, which is closely related to the past surface air temperature change. This method can be applied to studies of thermal environment evolution in urban areas such as the development of "heat islands". We have been investigating GST histories in three areas, which are located in Japan and Thailand. The three areas are the northern part of Kanto area, Osaka area, and Bangkok area. Kanto area and Osaka area have the greatest and second greatest population in Japan, each other. Bangkok area has the greatest population in Thailand. In the northern part of Kanto area, we conducted measurements of temperature profiles in groundwater monitoring wells at 25 sites in 2009, 2010, and 2011. In Osaka area, temperature profiles were measured at 31 sites in 2011 as the project of the Sumitomo Foundation (M. Taniguchi). In Bangkok area, we measured temperature profiles at 45 sites in 2004, 2006, 2008, and 2010. We examined the shapes of the temperature profiles and selected ones that are not significantly disturbed by groundwater flow. Reconstruction of GST history for the last about 300 hundred years was made at two sites in the northern part of Kanto area, at six sites in Osaka area, and at six sites in Bangkok area. We used a multi-layer model that allows layers with different thermal properties, determining layer boundaries based on lithology of the formations around the wells. All of the reconstructed GST histories show surface warming in the last century. In the northern part of Kanto area, the amount of the temperature increase from 1700 to 2010 is about 2.5 K at both sites. In Osaka area, the amount of the temperature increase from 1700 to 2010 ranges from 2.5 K to 5.0 K and is larger in the city center and the southern part

  7. Monitoring of atmospheric particles over an urban area

    NASA Astrophysics Data System (ADS)

    Mukai, S.; Sano, I.; Yasumoto, M.

    It is known that optical properties of atmospheric aerosols are important for the Earth s radiation budget and global climate It is also known that Asia is the most complicated region for aerosol study because the dust particles come from continental desert area carbonaceous aerosols are produced by large Siberian biomass-burning plumes and small anthropogenic particles are emitted from the increasing industrial activities Simultaneous measurements of atmospheric aerosols and suspended particulate matter SPM have been undertaken at Kinki University campus in Higashi-Osaka in order to monitor the urban environment during more than two years The sun sky photometry has been made as a NASA AERONET station since 2002 and the SPM-613D Ki-moto Electric has been taking measurements of the SPM concentrations such as TSP PM 10 PM 2 5 and OBC at the same site since March 15 2004 This long term simul-taneous monitoring of aerosols and SPM provides us with typical aerosol types over an industrial city of Higashi-Osaka and the relationship between aerosol properties obtained from radiometry with AERONET and the SPM measurements as 1 The air quality of the Higashi-Osaka site is poor due to not only anthropogenic particles by local emissions such as diesel vehicles and chemical industries but also due to dust particles and biomass-burning aerosols by large scale climatic conditions 2 Fine anthropogenic particles dominate at Higashi-Osaka even during dust events It is of interest to mention that dust events at Higashi-Osaka seem to be

  8. Report on support activity for the East Japan Great Earthquake (May 27-29, 2011).

    PubMed

    Ooe, Yosuke

    2012-07-01

    The M9.0 great earthquake that occurred on March 11, 2011 triggered a huge tsunami on the Pacific coast in the Tohoku region and caused enormous damage, resulting in 15,854 deaths and 3,276 missing persons (as of March 1, 2012, according to the Japanese National Police Agency). Presently, inhabitants in Fukushima Prefecture continue to live as refugees because of radiation contamination caused by explosions at the Fukushima nuclear power plants. Immediately after the earthquake, DMATs (Disaster Medical Assistance Teams) went to the affected areas to begin relief operations. The Japan Medical Association then founded the JMAT (Japan Medical Association Team), an organization to take over DMAT activities. The purpose of JMAT is (1) to assist hospitals and clinics in affected areas with daily care and (2) to provide medical care in refuge and aid stations. The Osaka Medical Association was assigned to be in charge of medical support in Iwate Prefecture. For medical services, team activities are more effective than individual efforts. Therefore, JMAT is basically a team composed of one doctor, two nurses, and one clerical officer. The team of Yao Municipal Hospital consists of two doctors, two nurses, two pharmaceutical chemists, and two office clerks. It is 13,000 km each way from Osaka to Iwate, and it is an estimated 15 hours by road. Our initial schedule was five days and four nights, leaving Osaka on the afternoon of May 26 and heading for Iwate on a chartered bus, engaging in medical care from the morning of May 27 to 30, leaving Iwate on the morning of May 30 and returning to Osaka that evening. However, since Hanamaki Airport in the inland area of Iwate Prefecture became usable starting in mid-May, we arrived in Hanamaki City by air and used a large taxi from the airport. In accordance with the recovery of local medical institutions, the Osaka Medical Association JAMT dispatch was to be terminated by the end of May. As a result, our team's itinerary was reduced

  9. Healthcare public key infrastructure (HPKI) and non-profit organization (NPO): essentials for healthcare data exchange.

    PubMed

    Takeda, Hiroshi; Matsumura, Yasushi; Nakagawa, Katsuhiko; Teratani, Tadamasa; Qiyan, Zhang; Kusuoka, Hideo; Matsuoka, Masami

    2004-01-01

    To share healthcare information and to promote cooperation among healthcare providers and customers (patients) under computerized network environment, a non-profit organization (NPO), named as OCHIS, was established at Osaka, Japan in 2003. Since security and confidentiality issues on the Internet have been major concerns in the OCHIS, the system has been based on healthcare public key infrastructure (HPKI), and found that there remained problems to be solved technically and operationally. An experimental study was conducted to elucidate the central and the local function in terms of a registration authority and a time stamp authority by contracting with the Ministry of Economics and Trading Industries in 2003. This paper describes the experimental design with NPO and the results of the study concerning message security and HPKI. The developed system has been operated practically in Osaka urban area.

  10. mDCC_tools: characterizing multi-modal atomic motions in molecular dynamics trajectories.

    PubMed

    Kasahara, Kota; Mohan, Neetha; Fukuda, Ikuo; Nakamura, Haruki

    2016-08-15

    We previously reported the multi-modal Dynamic Cross Correlation (mDCC) method for analyzing molecular dynamics trajectories. This method quantifies the correlation coefficients of atomic motions with complex multi-modal behaviors by using a Bayesian-based pattern recognition technique that can effectively capture transiently formed, unstable interactions. Here, we present an open source toolkit for performing the mDCC analysis, including pattern recognitions, complex network analyses and visualizations. We include a tutorial document that thoroughly explains how to apply this toolkit for an analysis, using the example trajectory of the 100 ns simulation of an engineered endothelin-1 peptide dimer. The source code is available for free at http://www.protein.osaka-u.ac.jp/rcsfp/pi/mdcctools/, implemented in C ++ and Python, and supported on Linux. kota.kasahara@protein.osaka-u.ac.jp Supplementary data are available at Bioinformatics online. © The Author 2016. Published by Oxford University Press.

  11. Dietary habits among the JPHC study participants at baseline survey. Japan Public Health Center-based Prospective Study on Cancer and Cardiovascular Diseases.

    PubMed

    Tsugane, S; Sasaki, S; Kobayashi, M; Tsubono, Y; Sobue, T

    2001-10-01

    Dietary habit is closely associated with development of cancer and cardiovascular diseases, however little prospective evidence has been published for Japanese, whose dietary habit is substantially different from Western countries. Therefore, frequencies of food consumption, food preference, cooking method and acceptance of dietary advice were investigated at the baseline by two kinds of self-administered food frequency questionnaires. Dietary habits between urban and rural (Tokyo and Osaka vs. others), or between Okinawa and non-Okinawa revealed recognizable differences. The so-called westernized foods such as bread, beef and coffee were more consumed in the urban areas such as Tokyo and Osaka and also in Okinawa. The frequencies of salted food intake such as pickled vegetables and salted seafoods were remarkably low in Okinawa. Cooking methods for meats, seafoods and vegetables were also unique in Okinawa. No distinct geographical difference was shown in food preference and modification of dietary habit by dietary advice.

  12. Development of Residential SOFC Cogeneration System

    NASA Astrophysics Data System (ADS)

    Ono, Takashi; Miyachi, Itaru; Suzuki, Minoru; Higaki, Katsuki

    2011-06-01

    Since 2001 Kyocera has been developing 1kW class Solid Oxide Fuel Cell (SOFC) for power generation system. We have developed a cell, stack, module and system. Since 2004, Kyocera and Osaka Gas Co., Ltd. have been developed SOFC residential co-generation system. From 2007, we took part in the "Demonstrative Research on Solid Oxide Fuel Cells" Project conducted by New Energy Foundation (NEF). Total 57 units of 0.7kW class SOFC cogeneration systems had been installed at residential houses. In spite of residential small power demand, the actual electric efficiency was about 40%(netAC,LHV), and high CO2 reduction performance was achieved by these systems. Hereafter, new joint development, Osaka Gas, Toyota Motors, Kyocera and Aisin Seiki, aims early commercialization of residential SOFC CHP system.

  13. Research and Development of Electrothermal Pulsed Plasma Thrusters onboard PROITERES Satellite

    NASA Astrophysics Data System (ADS)

    Tahara, Hirokazu; Naka, Masamichi; Takagi, Hiroki; Ikeda, Tomoyuki; Watanabe, Yosuke

    2010-10-01

    The Project of Osaka Institute of Technology Electric-Rocket-Engine onboard Small Space Ship (PROITERES) was started at Osaka Institute of Technology. In PROITERES, a small satellite with electrothermal pulsed plasma thrusters (PPTs) will be launched in 2010. The main mission is powered flight of small satellite by electric thruster. This study aims at improvement in performance by changing configuration of PPTs. The total impulse of about 5 Ns was achieved with a Teflon® (poly-tetrafluoroethylene: PTFE) cylindrical discharge room of 9.0 mm in length and 1.0 mm in diameter in 53,000-shot operation with 2.43 J/shot. Finally, the engineering model of the PPT system was developed, and it is under operation as final test.

  14. Construction of In-house Databases in a Corporation

    NASA Astrophysics Data System (ADS)

    Kato, Toshio

    Osaka Gas Co., Ltd. constructed Osaka Gas Technical Information System (OGTIS) in 1979, which stores and retrieves the in-house technical information and provides even primary materials by unifying optical disk files, facsimile system and so on. The major information sources are technical materials, survey materials, planning documents, design materials, research reports, business tour reports which are all generated inside the Company. At the present moment it amounts to 25,000 items in total adding 1,000 items annually. The data file is updated once in a month and also outputs the abstract journal OGTIS Report monthly. In 1983 it constructed System for International Exchange of Personal Information (SIP) as a subsystem of OGTIS in order to compile SIP database which covers exchange outlines with oversea enterprises or organizations. The data size is 2,600 totally adding about 500 annually with monthly data updating.

  15. Foam materials for cryogenic targets of fast ignition realization experiment (FIREX)

    NASA Astrophysics Data System (ADS)

    Nagai, Keiji; Azechi, H.; Ito, F.; Iwamoto, A.; Izawa, Y.; Johzaki, T.; Kodama, R.; Mima, K.; Mito, T.; Nakai, M.; Nemoto, N.; Norimatsu, T.; Ono, Y.; Shigemori, K.; Shiraga, H.; Tanaka, K. A.

    2005-11-01

    Development of foam materials for cryogenically cooled fuel targets is described in this paper. The fabrication development was initiated as a part of the fast ignition realization experiment (FIREX) project at the ILE, Osaka University under a bilateral collaboration between Osaka University and National Institute for Fusion Science (NIFS). For the first stage of FIREX (FIREX-I), a foam cryogenic target was designed in which low-density foam shells with a conical light guide will be fuelled through a narrow pipe and will be cooled down to the cryogenic temperature. Acrylic polymer, resorcinol-formaldehyde (RF) resin, poly(4-methyl-1-pentene) (PMP), and polystyrene-based crosslinking polymer have been investigated as supporting materials for cryogenic fuel. The properties of the material and the present status of the material development are summarized.

  16. mDCC_tools: characterizing multi-modal atomic motions in molecular dynamics trajectories

    PubMed Central

    Kasahara, Kota; Mohan, Neetha; Fukuda, Ikuo; Nakamura, Haruki

    2016-01-01

    Summary: We previously reported the multi-modal Dynamic Cross Correlation (mDCC) method for analyzing molecular dynamics trajectories. This method quantifies the correlation coefficients of atomic motions with complex multi-modal behaviors by using a Bayesian-based pattern recognition technique that can effectively capture transiently formed, unstable interactions. Here, we present an open source toolkit for performing the mDCC analysis, including pattern recognitions, complex network analyses and visualizations. We include a tutorial document that thoroughly explains how to apply this toolkit for an analysis, using the example trajectory of the 100 ns simulation of an engineered endothelin-1 peptide dimer. Availability and implementation: The source code is available for free at http://www.protein.osaka-u.ac.jp/rcsfp/pi/mdcctools/, implemented in C ++ and Python, and supported on Linux. Contact: kota.kasahara@protein.osaka-u.ac.jp Supplementary information: Supplementary data are available at Bioinformatics online. PMID:27153575

  17. Comparison of Emla cream and topical lidocaine tape for pain relief of V-beam laser treatment.

    PubMed

    Horikiri, Masaru; Ueda, Kazuki; Sakaba, Takao

    2017-06-23

    The authors compared the analgesic effects of two topical applications; Emla(®) cream (Sato Pharmaceutical Co. Ltd., Tokyo, Japan) and 60% lidocaine tape (Penles(®) tape; Maruho, Osaka, Japan). The authors examined 20 outpatients with capillary malformations. Emla(®) cream or Penles(®) tape was applied 1 h before laser irradiation using V-Beam. After V-Beam irradiation, pain intensity was measured using Pain Vision(®) (NIPRO, Osaka, Japan), while subjective pain was converted into numerical values using the VAS system. In the assessment using Pain Vision(®), pain was significantly lower in patients who received Emla(®) cream (Welch test), whereas no difference was observed in VAS ratings between the two applications (student's t test). The objective system showed that Emla(®) cream had a significantly greater analgesic effect. We plan to evaluate the analgesic effects of these topical anesthetics by applying them to other anatomical areas.

  18. Copy number loss in the region of the ASPN gene in patients with acetabular dysplasia: ASPN CNV in acetabular dysplasia.

    PubMed

    Sekimoto, T; Ishii, M; Emi, M; Kurogi, S; Funamoto, T; Yonezawa, Y; Tajima, T; Sakamoto, T; Hamada, H; Chosa, E

    2017-07-01

    We have previously investigated an association between the genome copy number variation (CNV) and acetabular dysplasia (AD). Hip osteoarthritis is associated with a genetic polymorphism in the aspartic acid repeat in the N-terminal region of the asporin (ASPN) gene; therefore, the present study aimed to investigate whether the CNV of ASPN is involved in the pathogenesis of AD. Acetabular coverage of all subjects was evaluated using radiological findings (Sharp angle, centre-edge (CE) angle, acetabular roof obliquity (ARO) angle, and minimum joint space width). Genomic DNA was extracted from peripheral blood leukocytes. Agilent's region-targeted high-density oligonucleotide tiling microarray was used to analyse 64 female AD patients and 32 female control subjects. All statistical analyses were performed using EZR software (Fisher's exact probability test, Pearson's correlation test, and Student's t-test). CNV analysis of the ASPN gene revealed a copy number loss in significantly more AD patients (9/64) than control subjects (0/32; p = 0.0212). This loss occurred within a 60 kb region on 9q22.31, which harbours the gene for ASPN. The mean radiological parameters of these AD patients were significantly worse than those of the other subjects (Sharp angle, p = 0.0056; CE angle, p = 0.0076; ARO angle, p = 0.0065), and all nine patients required operative therapy such as total hip arthroplasty or pelvic osteotomy. Moreover, six of these nine patients had a history of operative or conservative therapy for developmental dysplasia of the hip. Copy number loss within the region harbouring the ASPN gene on 9q22.31 is associated with severe AD. A copy number loss in the ASPN gene region may play a role in the aetiology of severe AD.Cite this article: T. Sekimoto, M. Ishii, M. Emi, S. Kurogi, T. Funamoto, Y. Yonezawa, T. Tajima, T. Sakamoto, H. Hamada, E. Chosa. Copy number loss in the region of the ASPN gene in patients with acetabular dysplasia: ASPN CNV in acetabular

  19. Views on Inertial Fusion Energy Development

    NASA Astrophysics Data System (ADS)

    Nakai, S.

    It is my great honor to receive the Edward Teller Award. Representing the Institute of Laser Engineering, Osaka University, I would like to appreciate your favorite recognition on our achievements in laser fusion research. Yesterday I talked the review of the activity and recent results of our Institute. This evening I would like to talk more personal feeling on the Inertial Fusion Energy development and surrounding conditions.

  20. Progress towards a laser produced relativistic electron-positron pair plasma

    DOE PAGES

    Chen, Hui; Bonlie, J.; Cauble, R.; ...

    2016-04-01

    Here, a set of experiments has been performed exploring unique characteristics of pair jets and plasmas at several energetic short-pulse laser facilities including Titan at Livermore and OMEGA EP in Rochester, as well as the Osaka LFEX and AWE Orion lasers. New results are summarized, including positron beam emittance, scaling of pair production vs. laser energy, and initial results on the pair jet collimation using electromagnetic fields.

  1. Progress towards a laser produced relativistic electron-positron pair plasma

    SciTech Connect

    Chen, Hui; Bonlie, J.; Cauble, R.; Fiuza, F.; Goldstein, W.; Hazi, A.; Keane, C.; Link, A.; Marley, E.; Nagel, S. R.; Park, J.; Shepherd, R.; Williams, G. J.; Meyerhofer, D. D.; Fiksel, G.; Barnak, D.; Chang, P. Y.; Nakai, M.; Arikawa, Y.; Azechi, H.; Fujioka, S.; Kojima, S.; Miyanaga, N.; Morita, T.; Nagai, T.; Nishimura, H.; Ozaki, T.; Sakawa, Y.; Takabe, H.; Zhang, Z.; Kerr, S.; Fedosejevs, R.; Sentoku, Y.; Hill, M. P.; Hoarty, D. J.; Hobbs, L. M. R.; James, S. F.

    2016-03-01

    Here, a set of experiments has been performed exploring unique characteristics of pair jets and plasmas at several energetic short-pulse laser facilities including Titan at Livermore and OMEGA EP in Rochester, as well as the Osaka LFEX and AWE Orion lasers. New results are summarized, including positron beam emittance, scaling of pair production vs. laser energy, and initial results on the pair jet collimation using electromagnetic fields.

  2. JPRS Report Science and Technology, Japan: Atomic Energy Society 1989 Annual Meeting.

    DTIC Science & Technology

    2007-11-02

    Post-Irradiation Examination of Fugen MOX Fuel Assembly Outline of the PIE [K. Asahi, K, Domoto, et al.] 24 Study of Np Separation Process in...state and land-sea breeze shift (for one hour). 23 Post-Irradiation Examination of Fugen MOX Fuel Assembly Outline of the PIE 43063046e Osaka...Introduction Fugen is the world’s first thermal neutron reactor to use MOX [mixed oxide] fuel in full scale, and it has steadily operated and provided

  3. JPRS Report, Science & Technology, Japan, STA Research on Superconducting Materials

    DTIC Science & Technology

    2007-11-02

    1986 Laboratory Niobium/ 2 wo0 germanium20 t’ ’’ -- 260 10 • Niobiumltin 1911 - 00Interalloy metal Liquid1911 -- S °mD°und <-Ihel~iu m 0 Mercury J...Toichi Okada Professor Industrial Science Research Laboratory, Osaka University Koichi Kitazawa Professor Engineering, University of Tokyo Ken Sugiura...0 . Crystal structure 0 Nagnetism Thermodynamic property Optical property Ov Basic property experiment si . 0 04 ’ s Liquid •Jnitrogeno ’ tempera- W o

  4. International Workshop on Membrane Biotechnology and Membrane Biomaterials (4th) Held in La Manga, Murcia, Spain on 29 May-2 June 1991.

    DTIC Science & Technology

    1991-06-02

    Quimica Fisica, Facultad de Farmacia, Universidad Complutense, 28040, Madrid, $pain DE MADARIAGA, M. Africa; Depto. de Bioquimica y Fisiologia , Facultad de...Suita,, Osaka, 565, Japan MORA, Margarita; Depto. de Bioquimica y Fisiologia , Facultad de Quimicas, Universidad de Barcelona, Marti i Franqu&s 1...Apartado 374, 03080-Alicante. Spain ROSELL, Francisco; Depto. de Bioquimica y Fisiologia , Facultad de Quimica, Universidad de Barcelona, Marti i Franqu~s 1

  5. A Highly intense DC muon source, MuSIC and muon CLFV search

    NASA Astrophysics Data System (ADS)

    Hino, Y.; Kuno, Y.; Sato, A.; Sakamoto, H.; Matsumoto, Y.; Tran, N. H.; Hashim, I. H.; Fukuda, M.; Hayashida, Y.; Ogitsu, T.; Yamamoto, A.; Yoshida, M.

    2014-08-01

    MuSIC is a new muon facility, which provides the world's highest intense muon beam with continuous time structure at Research Center of Nuclear Physics (RCNP), Osaka University. It's intensity is designed to be 108 muons per second with only 0.4 kW proton beam. Such a high intense muon beam is very important for searches of rare decay processes, for example search for the muon to electron conversion.

  6. [Increase of poisoning by tropical mushrooms in Japan in recent years].

    PubMed

    Yokoyama, Kazumasa; Gonmori, Kunio

    2009-09-01

    A tropical poisonous mushroom, Chlorophyllum molybdites, invaded into Japan in recent years, and distributed in south-eastern and central part of Japan including 27 Prefectures in 2009; Gunma, Tochigi, Saitama, Ibaraki, Tokyo (including Bonin Islands), Chiba, Shizuoka, Ishikawa, Aichi, Mie, Shiga, Kyoto, Nara, Osaka, Wakayama, Hyogo, Tottori, Okayama, Hiroshima, Yamaguchi, Kagawa, Tokushima, Kochi, Ohita, Kumamoto, Kagoshima and Okinawa. Poisoning by this fungus has increased recently (Table 2). Topics on distribution and poisoning by Russula subnigricans and Podostroma cornu-damae briefly discussed.

  7. 919: Evidence for K{sup +} {r_arrow} {pi}{sup +} {nu}{bar {nu}} from E787

    SciTech Connect

    Frank, J.S.; E787 Collaboration

    1997-12-01

    A collaboration from KEK, INS, Osaka, TRIUMF, Princeton, and BNL is currently running E787 at the AGS. The experiment is designed primarily to search for the rare decay K{sup +} {yields} {pi}{sup +}{nu}{bar {nu}}, with an expected branching ratio of {approximately} 10{sup {minus}10}. The authors report evidence that they have observed this decay. They also discuss the future outlook for the experiment.

  8. Small geographic variation in photoperiodic entrainment of the circannual rhythm in the varied carpet beetle, Anthrenus verbasci.

    PubMed

    Matsuno, Tomoya; Kawasaki, Yuta; Numata, Hideharu

    2013-04-01

    The circannual pupation rhythm of Anthrenus verbasci is entrained to an environmental cycle by changes in photoperiod. Exposure of larvae reared under short-day conditions to long days induced a clear phase delay of the circannual rhythm. There was no notable difference in the initial phase or period of the circannual rhythm among four geographically distinct populations of A. verbasci in Japan: Takanabe (32.1°N), Osaka (34.7°N), Sendai (38.3°N), and Sapporo (43.1°N) populations. The range of photoperiodic changes effective for phase delay in the circannual pupation rhythm was compared among the four populations. Although larvae did not show a typical threshold response, but responded quantitatively to the photophase duration in intermediate conditions, the critical daylengths were calculated as those under which the pupation was delayed by 50%: 12.8 h in the Takanabe population, 13.2 h in the Osaka population, and 13.6 h in the Sendai and Sapporo populations. Thus, the critical daylength for entrainment of the circannual rhythm in A. verbasci was correlated to the habitat latitude, but the differences among the populations were much smaller than those reported in photoperiodism for induction of diapause in various insects. Consequently, the difference in the pupation time among the four geographic populations was very small under the natural photoperiod in Osaka at 20°C, and absent under the natural photoperiod and temperature in Osaka. These results suggest that A. verbasci survives and successfully produces the next generation in different geographic regions without changing the parameters of the circannual rhythm.

  9. On-line Robot Adaptation to Environmental Change

    DTIC Science & Technology

    2005-08-01

    background needed to understand the thesis . This robotic system was originally de- veloped for use in the RoboCup Sony legged league which is an...The league currently uses the ERS-7 AIBO model. This platform was used for all of the robotic testing in this thesis . In the legged league...Carnegie Mellon University Pittsburgh, PA 15213 Thesis Committee: Manuela Veloso, Chair Takeo Kanade Anthony Stentz Minoru Asada, Osaka University, Japan

  10. Corrosion Screening of EV31A Magnesium and Other Magnesium Alloys using Laboratory-Based Accelerated Corrosion and Electro-Chemical Methods

    DTIC Science & Technology

    2014-07-01

    Welding Research Institute of Osaka University, Japan, for supplying magnesium samples used to produce the specimens in this study. The authors also thank...design and coatings, engineers now mitigate corrosion through proper joint design, insulation of dissimilar metals, manufacturing process controls...materials selection and electrical and moisture isolation of the Mg from all dissimilar metals. 5. Conclusions • Overall, there was good agreement

  11. Southeast Asia Report.

    DTIC Science & Technology

    1987-05-27

    with Aspertame (which is 180 times sweeter than sucrose), Acesulfam-K (which is a non-calorific intensely sweet organic salt) and high fructose corn ...Osaka, Asks More Japanese Investment (KYODO, 27 Apr 87) 25 Japan Considering Visa Ban on Filipinas (Chay 0. Florentino; PHILIPPINE DAILY...The Defence Signals Directorate’s earlier antennas for intercepting and locating normal high -frequency transmissions have been improved at major

  12. ['Surgery by the red-haired barbarians'; Dutch physicians in Japan, 1600-1870].

    PubMed

    Veldman, J E

    2001-12-29

    Approximately 400 years ago, Dutch physicians laid the foundations for Western medicine in Japan. Around 1860, Dutch naval surgeons, trainees of the College of Army Surgeons in Utrecht, were to become the founders of the Medical Faculties at the Universities of Nagasaki, Tokyo and Osaka. The earlier Deshima-settlement surgeons Engelbert Kaempfer and Philipp Franz von Siebold played a highly important role in our knowledge of Japan during the 18th and 19th centuries.

  13. Development of Fudai Sun Sensor (FSS)

    NASA Astrophysics Data System (ADS)

    Obata, Takatoshi; Itoh, Hideaki; Kakimi, Yukitaka; Okubo, Hiroshi

    This paper describes the design process of the Fudai sun sensor (FSS) installed in a 50-kg-class micro-satellite, SOHLA-1. The FSS has been developed by the students of Osaka Prefecture University (OPU) with technical support from the Japan Aerospace Exploration Agency (JAXA) and Advanced Engineering Services (AES) Co. Ltd. In this project, the students experienced a series of processes required for developing satellite components, namely, design, production, test, launch, and operation.

  14. Compact and Easy-Operation Magnetocardiograph With Four-Channel Planar Gradiometers

    DTIC Science & Technology

    2007-11-02

    using fetal magnetocardiography ,” Prenat. Diagn., vol. 19, pp. 677-680, 1999. [4] S. Yamada et al., “Noninvasive diagnosis of arrhythmic foci by using...generated by human hearts. MCG has been applied to diagnosis of ischemic [1, 2] or fetal [3] heart disease and estimation of the region of arrhythmia...8] D. Suzuki et al., “Simplified magnetically shielded cylinder for high Tc SQUID magnetocardiography system,” Presented at the ISEC ’01 (Osaka), 2001

  15. Progress Towards a Laser Produced Relativistic Electron-Positron Pair Plasma

    NASA Astrophysics Data System (ADS)

    Chen, Hui; Bonlie, J.; Cauble, R.; Fiuza, F.; Goldstein, W.; Hazi, A.; Keane, C.; Link, A.; Marley, E.; Nagel, S. R.; Park, J.; Shepherd, R.; Williams, G. J.; Meyerhofer, D. D.; Fiksel, G.; Barnak, D.; Chang, P. Y.; Nakai, M.; Arikawa, Y.; Azechi, H.; Fujioka, S.; Kojima, S.; Miyanaga, N.; Morita, T.; Nagai, T.; Nishimura, H.; Ozaki, T.; Sakawa, Y.; Takabe, H.; Zhang, Z.; Kerr, S.; Fedosejevs, R.; Sentoku, Y.; Hill, M. P.; Hoarty, D. J.; Hobbs, L. M. R.; James, S. F.

    2016-03-01

    A set of experiments has been performed exploring unique characteristics of pair jets and plasmas at several energetic short-pulse laser facilities including Titan at Livermore and OMEGA EP in Rochester, as well as the Osaka LFEX and AWE Orion lasers. New results are summarized, including positron beam emittance, scaling of pair production vs. laser energy, and initial results on the pair jet collimation using electromagnetic fields.

  16. Optical Material Researches for Frontier Optical Ceramics and Visible Fiber Laser Technologies

    DTIC Science & Technology

    2016-07-07

    AFRL-AFOSR-JP-TR-2016-0059 Optical material researches for frontier optical ceramics and visible fiber laser technologies Yasushi Fujimoto Osaka...07-2016 2. REPORT TYPE Final 3. DATES COVERED (From - To) 18 Apr 2013 to 17 Apr 2016 4. TITLE AND SUBTITLE Optical material researches for frontier...are very useful for scientific and industrial applications. 15. SUBJECT TERMS Fibre Lasers, Laser Dynamics, Nonlinear Optical Materials 16. SECURITY

  17. Comparative analysis of Micrococcus luteus isolates from blood cultures of patients with pulmonary hypertension receiving epoprostenol continuous infusion.

    PubMed

    Hirata, Yoshinori; Sata, Makoto; Makiuchi, Yuko; Morikane, Keita; Wada, Akihito; Okabe, Nobuhiko; Tomoike, Hitonobu

    2009-12-01

    During the period 2002-2008, at the National Cardiovascular Center, Osaka, 28 Micrococcus luteus isolates and one Kocuria spp. isolate were obtained from blood cultures of pulmonary hypertension (PH) patients who were receiving continuous infusion therapy with epoprostenol. Pulsed-field gel electrophoresis patterns of the isolates were unrelated, suggesting that the infections had multiple origins. The preparation of epoprostenol solution by patients themselves was thought to be a risk factor.

  18. Beam divergence characteristic of two-stage ion diode

    NASA Astrophysics Data System (ADS)

    Shirai, Nobutake; Yasuike, Kazuhito; Takahashi, Genji; Shomoto, Norihisa; Yamamoto, Kazuhiro; Imasaki, Kazuo; Yamanaka, Chiyoe; Miyamoto, Shuji; Nakai, Sadao

    1994-06-01

    The improvement of beam divergence by a two-stage diode is being studied at ILE Osaka University. We measured 750 keV carbon beam divergence by using a Shadow-Box with CR-39. We used the track analyzer (LUZEX III) that could measure and digitize the position of tracks, track diameter and shape of tracks to count a number of tracks on CR-39 and obtained results of beam divergence at first stage and second stage with track diameter resolution.

  19. Measurement of γ-rays from Giant Resonances of 16O and 12C with Application to Supernova Neutrino Detection

    NASA Astrophysics Data System (ADS)

    Ou, Iwa; Yamada, Yoshiyuyki; Shirahige, Tetsuya; Fukuda, Daisuke; Yano, Takatomi; Mori, Takaaki; Koshio, Yusuke; Sakuda, Makoto; Dhir, Rohit; Tamii, Atsushi; Aoi, Nori; Yosoi, Masaru; Ideguchi, Eiji; Suzuki, Tomokazu; Iwamoto, Chihiro; Ito, Takeshi; Miura, Masaki; Yamamoto, Tetsuya; Kawabata, Takahiro; Adachi, Satoshi; Tsumura, Miho; Murata, Motoki; Furuno, Tatsuya; Akimune, Hidetoshi; Nakada, Hitoshi

    We report preliminary results on the detection of the γ-rays from giant resonances of 16O and 12C nuclei from the experiment carried out at Research Center for Nuclear Physics Osaka University. These γ-rays can be used to detect the μ and τ type neutrinos and anti-neutrinos, emitted from a core-collapse supernova, through neutral current reactions with 16O and 12C by large-scale neutrino detectors.

  20. From Theory to Air Force Practice: Applications and Non-Binary Extensions of Probabilistic Model-Building Genetic Algorithms

    DTIC Science & Technology

    2006-05-31

    University , Barcelona, Spain) 3. Dr. Hussein Abbass ( University of New South Wales, Australian Defence Force Campus) 4. Dr. Kei Ohnishi (Kyushu... University , Japan) 5. Dr. Naohiro Matsumura ( Osaka University , Japan) Graduate student affiliates. The following is a list of graduate students supported or...TASK NUMBER DX 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) 8. PERFORMING ORGANIZATION UNIVERSITY OF ILLINOIS AT URBANA

  1. [Historical study of the moth repellent, "Fujisawa Camphor" (3) An exposition as an advertisement media].

    PubMed

    Hattori, Akira

    2003-01-01

    Newspaper advertisements were the predominant medium in informing people about new products midway through the Meiji Era. Subscribers to these newspapers, however, were still limited. At the time, expositions were wildly popular. Seizing the opportunity , in 1903 Fujisawa promoted his "Fujisawa Camphor" through aggressive advertising at the 5th Domestic Industrial Exposition in Osaka. The advertising proved to be a success, as Fujisawa took 2nd Prize of the exposition.

  2. Creative Exercises for Cultivation of Creative Activities

    NASA Astrophysics Data System (ADS)

    Motoba, Toshio; An, Hiroshi; Ozasa, Toshihiro; Masutani, Yasuhiro; Mori, Koji; Yasutomi, Masanori; Yoshida, Haruyuki

    “Creative Exercise” is one of the most important articles in the course of technology educations at the universities and the colleges. In this paper, some trials for the creative exercises developed in Osaka Electro-Communication University are introduced ; those are (1) exercises in “Creative Design Engineering”, (2) studies and educations on robots, (3) executive plan of rescue-robot contest, and (4) supporting system for application for the qualifying examinations. Their results and effectiveness are also discussed.

  3. [Activity and Future Perspective of Local Independent Clinical Trial Group (OGSG)].

    PubMed

    Tsujinaka, Toshimasa

    2016-04-01

    Osaka Gastrointestinal Cancer Chemotherapy Study Group (OGSG) was established in 2000 and has been conducting investigator initiated multi-institutional collaboration trials regarding the treatment of gastrointestinal cancer, especially using chemotherapeutic agents. Although organization of OGSG has been renovated to perform post-marketing clinical trials with high quality, OGSG is now facing severe financial crisis because of shortage of donation from pharmaceutical companies. Here, present problems and future perspectives are discussed.

  4. Management of Bottom Sediments Containing Toxic Substances. Proceedings of the U.S./Japan Experts Meeting (8th) Held at Tokyo, Japan on 8-10 November 1982

    DTIC Science & Technology

    1984-07-01

    and Harbour Bureau, City of Osaka, Japan 1130-1200 N. E . Parker, "Constructive Use of Dredged Sand," Coastal Engi- neering Research Center, Corps of...was designed to test and evaluate the hypothesis that sand "dredged from a coastal inlet and placed seaward of the surf zone will effectively...placed was distributed by littoral processes. The 1978 experiment was designed to test and evaluate the effects of increased pla’cement depth on

  5. Virulence determinants of pandemic A(H1N1)2009 influenza virus in a mouse model.

    PubMed

    Uraki, Ryuta; Kiso, Maki; Shinya, Kyoko; Goto, Hideo; Takano, Ryo; Iwatsuki-Horimoto, Kiyoko; Takahashi, Kazuo; Daniels, Rod S; Hungnes, Olav; Watanabe, Tokiko; Kawaoka, Yoshihiro

    2013-02-01

    A novel swine-origin H1N1 influenza virus [A(H1N1)pdm09 virus] caused the 2009 influenza pandemic. Most patients exhibited mild symptoms similar to seasonal influenza, but some experienced severe clinical signs and, in the worst cases, died. Such differences in symptoms are generally associated with preexisting medical conditions, but recent reports indicate the possible involvement of viral factors in clinical severity. To better understand the mechanism of pathogenicity of the A(H1N1)pdm09 virus, here, we compared five viruses that are genetically similar but were isolated from patients with either severe or mild symptoms. In a mouse model, A/Norway/3487/2009 (Norway3487) virus exhibited greater pathogenicity than did A/Osaka/164/2009 (Osaka164) virus. By exploiting reassortant viruses between these two viruses, we found that viruses possessing the hemagglutinin (HA) gene of Norway3487 in the genetic background of Osaka164 were more pathogenic in mice than other reassortant viruses, indicating a role for HA in the high virulence of Norway3487 virus. Intriguingly, a virus possessing HA, NA, and NS derived from Norway3487 exhibited greater pathogenicity in mice in concert with PB2 and PB1 derived from Osaka164 than did the parental Norway3487 virus. These findings demonstrate that reassortment between A(H1N1)pdm09 viruses can lead to increased pathogenicity and highlight the need for continued surveillance of A(H1N1)pdm09 viruses.

  6. Diallyl phthalate prepolymer characterization and testing in fiberglass filled molding compounds

    SciTech Connect

    Whitaker, R.B.; Schneider, R.E.; Schumacher, R.J.

    1983-02-21

    A program was undertaken to identify an acceptable alternative to Dapon 35, an o-diallyl phthalate (DAP) prepolymer no longer available. Three o-DAP prepolymers from the Osaka Soda Company and four laboratory-scale prepolymers from Bendix-Kansas city were characterized and evaluated in DAP-fiberglass molding compounds. Gel permeation chromatography results for the Osaka prepolymers showed all three to be very close to one another in molecular weights (mw) and mw distributions, but slightly lower in both than Dapon 35. They are also slightly higher in monomer content. All three processed readily into DAP-fiberglass molding compounds and passed required physical property tests. One Osaka prepolymer was compounded into both asbestos and Orlon-DAP compounds on a production scale. Both compounds have passed all certification tests. The Bendix prepolymers were deliberately varied in mw and mw distribution and higher in monomer content than Dapon 35. Processing difficulties were encountered with both the lowest and highest molecular weight compounds, and the lowest molecular weight compound failed a number of physical property tests. The two intermediate molecular weight compounds processed readily and passed property tests. Guidelines were established for acceptable o-DAP prepolymers: (1) weight average mw (relative to polystyrene standards): 30,000 to 150,000; (2) mw distribution: 3.0 to less than or equal to 18.0; and (3) DAP monomer content: 1.0 to less than or equal to 6.0%. 5 figures, 6 tables.

  7. Hydro-environmental changes and their influence on the subsurface environment in the context of urban development.

    PubMed

    Yoshikoshi, Akihisa; Adachi, Itsu; Taniguchi, Tomomasa; Kagawa, Yuichi; Kato, Masahiro; Yamashita, Akio; Todokoro, Taiko; Taniguchi, Makoto

    2009-04-15

    The relationship between urban development and hydro-environmental change, particularly with regard to the subsurface environment is examined for three coastal cities affected by Asian monsoons (Tokyo and Osaka in Japan, and Bangkok in Thailand). Major differences in subsurface changes among these cities are closely related to city size, urban structure, and the timing, stage and extent of urbanization as well as the natural environment. The work shows that the urban development has not affected the Bangkok subsurface hydro-environment in the same way it has in Tokyo and Osaka. Three reasons for the difference account for this, (1) Bangkok's abundant annual rainfall, (2) Bangkok has the smallest ratio of impervious pavement surface area, meaning that surface water can more easily infiltrate underground., (3) the degree and extent of urbanization. Bangkok's subsurface hydro-environment has not been heavily affected because underground development has not yet reached deep subterranean areas. By researching yet more cities, at different stages of urbanization to that of Tokyo, Osaka and Bangkok, we plan to quantitatively examine urbanization and its influence on subsurface hydro-environments. This research will help limit damage to developing cities that are not yet experiencing subsurface failures but which are expected to confront these problems in the future.

  8. Relations between radiotherapy resources and breast cancer patient survival rates.

    PubMed

    Mochimaru, Yuko; Ohno, Yuko; Numasaki, Hodaka; Theshima, Teruki; Shibuya, Hitoshi

    2010-01-01

    In Japan, the number of patients that have been treated with radiotherapy (RT), particularly those with breast cancer, has increased in the past decade, and is expected to double in the next decade. There is, however, a shortage of RT resources, particularly personnel, which represents a social problem. The shortage of RT resources might cause a difference in survival rate among treated patients. This study analyzed the characteristics of RT resources in RT facilities from Osaka based on the Japanese Society for Therapeutic Radiology and Oncology (JASTRO) database with principle component analysis and cluster analysis. In addition, the relation between RT resources and treatment outcome of breast cancer patients was investigated by linking together Osaka Cancer Registry (OCR) and JASTRO data via a stratified key cord. By using the linked dataset it was shown that the prognosis of breast cancer patients was highly correlated with the scale of RT resources available at the RT facilities collaterally. From cluster analysis, four groups were identified based on RT facility information. The breast cancer survival rates for localized stage patients obtained in classified hospital groups showed a similar pattern, however, large differences (up to 20%) were seen in regional stage patients. Additional findings were: RT facilities with less than 1 radiation oncologist had the poorest outcome; RT was performed primarily at University hospitals; and differences in RT resources within the RT facilities had an effect on breast cancer patient prognosis in Osaka, Japan.

  9. Development of remote surgical navigation and biopsy needle guidance system using Open-MRI and high-speed network

    NASA Astrophysics Data System (ADS)

    Okura, Yasuhiko; Matsumura, Yasushi; Kuwata, Shigeki; Takeda, Hiroshi

    2004-05-01

    This study describes a remote surgical guidance and navigation system developed for surgery using "Open-MRI" and high-speed network. We connected Osaka University Hospital and Kawasaki Hospital which has deployed Open- MRI with high speed IP over ATM network. The distance between two hospitals is approximately 50 km. Two video cameras were installed with an angle of 40 degrees on an open-MRI gantry to obtain intraoperative images. Two pairs of CODEC (AD/DA converter) were equipped on the network to transfer both images and sound in real time. A pointer system to indicate a region on an image was also developed. MRI images obtained by Open-MRI were transferred to a 3D workstation in Osaka University Hospital. The system was designed for a senior surgeon in Osaka University to advise regarding accurate needle direction for a remote patient by checking the reconstructed 3D images and schemata shown by the navigation software. The schemata were also superimposed on intraoperative images from two cameras, and the superimposed images were sent back to Kawasaki Hospital. This system allowed a surgeon in the operation room at Kawasaki Hospital to accurately view navigation schema under supervision by a senior surgeon in a remote university hospital with superimposion of intraoperative images. The pointer system allowed both doctors to share intraoperative images during a virtual-real surgical operation. A successful biopsy case using this newly developed system illustrates the effectiveness of this system.

  10. [Regional development planning and migration: the fourth comprehensive national development plan].

    PubMed

    Wakabayashi, K

    1987-04-01

    In 1986, the National Land Agency of Japan published the Development Plan for the National Capital Region and the outline of the 4th Comprehensive National Development Plan. Ever since the 1st Comprehensive National Development Plan in 1962, basic objectives of the plans have been well-balanced development of national land, adjustment of regional disparities, and dissolution of overcongestion and depopulation. Japan experienced rapid urbanization in the period from the war reconstruction of the 1940s through the high economic growth of the 1950s and 1960s. Particularly, during the high economic growth of the 1960s, the concentration of population and industry was extremely notable in the 3 metropolitan regions centering around Tokyo, Osaka, and Nagoya. There are indications of increases in excess migration to metropolitan regions once again, but this is due to increases of migration only to the Tokyo Metropolitan Regions. No such indications are seen for the Nagoya and Osaka Metropolitan Regions. Tokyo Metropolitan Regions are changing more and more, as a important international center of banking and information in the world; on the other hand, Osaka is lessening its sphere of influence. Particularly, from the 1980s, the concentration of population and nucleus functional institutions is extremely notable in the Tokyo Metropolitan Regions. The main objective of this paper is to analyze Tokyo New Industrial Cities, and other depopulated areas, through the distribution of population and the location of industry.

  11. [Measurement of external pressure of peroneal nerve tract coming in contact with lithotomy leg holders using pressure distribution measurement system BIG-MAT®].

    PubMed

    Mizuno, Ju; Namba, Chikara; Takahashi, Toru

    2014-10-01

    We investigated external pressure on peroneal nerve tract coming in contact with two kinds of leg holders using pressure distribution measurement system BIG- MAT® (Nitta Corp., Osaka) in the lithotomy position Peak contact (active) pressure at the left fibular head region coming in contact with knee-crutch-type leg holder M® (Takara Belmont Corp., Osaka), which supports the left popliteal fossa, was 78.0 ± 26.4 mmHg. On the other hand, peak contact pressure at the left lateral lower leg region coming in contact with boot-support-type leg holder Bel Flex® (Takara Belmont Corp., Osaka), which supports the left lower leg and foot was 26.3±7.9 mmHg. These results suggest that use of knee-crutch-type leg holder is more likely to induce common peroneal nerve palsy at the fibular head region, but use of boot-support-type leg holder dose not easily induce superficial peroneal nerve palsy at the lateral lower leg region, because capillary blood pressure is known to be 32 mmHg. Safer holders for positioning will be developed to prevent nerve palsy based on the analysis of chronological change in external pressure using BIG-MAT® system during anesthesia.

  12. Lightning Imaging via VHF Emission

    NASA Astrophysics Data System (ADS)

    Kawasaki, Z.

    2015-12-01

    Osaka University has been developing interferometric lightning mapping systems for some time, first with narrow band VHF interferometers, and then with broadband digital VHF interferometers (DITF). Recently, a collaboration between New Mexico Tech and Osaka University resulted in the development of the NMT INTF. All of these interferometric lightning mapping systems have added greatly to our understanding of lightning physics. The next generation of digital broadband VHF interferometer is now being developed in Osaka, called the Lightning Imaging via VHF Emission (LIVE) interferometer. LIVE is capable of mapping lightning in real-time with sub-millisecond time resolution, or through post processing with sub-microsecond time resolution. Near-field corrections have been developed, so that sources very close to the array can be located accurately, and so that the baselines can lengthened for improved angular resolution. LIVE is capable of locating lighting over more than a 75 dB range of brightnesses, allowing the system to be extremely sensitive, and the long baselines allow for location uncertainties as low as tens of meters. Presented are observations of lightning recorded in the Kasai area of Japan, as well as the Pengerang region of Malaysia showing the capabilities of the LIVE interferometer.

  13. [J-GRID and SATREPS programs in Thailand].

    PubMed

    Kameoka, Masanori; Sasaki, Tadahiro

    2013-01-01

    Thailand-Japan Research Collaboration Center on Emerging and Re-emerging Infections (RCC-ERI) was established in 2005 as a research collaboration center cooperated by Research Institute for Microbial Diseases (RIMD), Osaka University and Department of Medical Sciences, Ministry of Public Health of Thailand. In addition, Mahidol-Osaka Center for Infectious Diseases (MOCID) was established in 2010, also as another research collaboration center cooperated by RIMD, Osaka University and Faculty of Tropical Medicine, Mahidol University. Epidemiological and basic studies on human pathogenic viruses have been conducted in RCC-ERI and MOCID. In this report, brief overviews of the research activities of both centers, as well as the phenotypic studies on the envelope glycoproteins of HIV-1 Thai strains that have been performed at RCC-ERI, are presented. SATREPS is a Japanese government program by the Japan Science and Technology Agency (JST) and the Japan International Cooperation Agency (JICA) that promotes international joint research targeting global issues. Our research group at RIMD have collaborated with the Ministry of Public Health - National Institute of Health (NIH) and Mahidol University in Thailand from 2008 as a four-years project. Our aim on this collaboration is to generate human monoclonal antibodies neutralizing infectious viral agents, hopefully to apply them to clinical field as "therapeutic antibodies". Here we introduce our trials in this project, especially on the generation of human monoclonal antibodies against dengue virus as well as against influenza virus that have been performed as collaboration between Thai and Japanese research groups.

  14. Fast ignition integrated experiments and high-gain point design

    SciTech Connect

    Shiraga, H.; Nagatomo, H.; Theobald, W.; Solodov, A. A.; Tabak, M.

    2014-04-17

    Here, integrated fast ignition experiments were performed at ILE, Osaka, and LLE, Rochester, in which a nanosecond driver laser implodes a deuterated plastic shell in front of the tip of a hollow metal cone and an intense ultrashort-pulse laser is injected through the cone to heat the compressed plasma. Based on the initial successful results of fast electron heating of cone-in-shell targets, large-energy short-pulse laser beam lines were constructed and became operational: OMEGA-EP at Rochester and LFEX at Osaka. Neutron enhancement due to heating with a ~kJ short-pulse laser has been demonstrated in the integrated experiments at Osaka and Rochester. The neutron yields are being analyzed by comparing the experimental results with simulations. Details of the fast electron beam transport and the electron energy deposition in the imploded fuel plasma are complicated and further studies are imperative. The hydrodynamics of the implosion was studied including the interaction of the imploded core plasma with the cone tip. Theory and simulation studies are presented on the hydrodynamics of a high-gain target for a fast ignition point design.

  15. Analysis of change of red tide species in Yodo River estuary by the numerical ecosystem model.

    PubMed

    Hayashi, Mitsuru; Yanagi, Tetsuo

    2008-01-01

    Occurrence number of red tides in Osaka Bay in Japan is more than 20 cases every year. Diatom red tide was dominant in Osaka Bay, but the non-diatom red tide was dominant in early 1990s. Therefore, the material cycling in Yodo River estuary in Osaka Bay during August from 1991 to 2000 was analyzed by using the numerical ecosystem model and field observation data to clarify the reasons of change in red tide species. Year-to-year variation in calculated concentration ratio of diatom to non-diatom corresponds to the variation in observed ratio of red tide days of diatom to non-diatom. Limiting nutrient of primary production is phosphate over the period. Diatom dominated from 1991 to 1993, but it was difficult for non-diatom to grow due to the limitation by physical condition. Non-diatom was able to grow because of good physical and nutrient conditions from 1994 to 1996. And diatom dominated again under the good physical condition, and phosphorus supply was not enough for non-diatom to grow from 1998 to 2000. Phosphate concentration in the lower layer of Yodo River estuary was important to the variation in red tide species in the upper layer of Yodo River estuary.

  16. Source Apportionment of PM2.5 using PMF and CMB: Comparison of the Effects of Transboundary and Local Pollutions in the Western Japan

    NASA Astrophysics Data System (ADS)

    Iijima, A.; Sugata, S.

    2014-12-01

    PM2.5 has become one of the most important aspects in recent air pollution issues. In Japan, the achievement rate of the environmental quality standard for PM2.5 is in a worse situation so far (43.3% for ambient air monitoring station, 33.3% for roadside air pollution monitoring station in FY2012). Therefore, source apportionment will be essential to policy and decision making for improving the PM2.5 pollution. Since 2011, we started the field monitoring study called "Current Status Elucidation and Source Contribution Assessment of PM2.5 Pollution in Collaboration with Environmental Research Institutes across Japan" which was granted by the Environment Research and Technology Development Fund (5B-1101) of the Ministry of the Environment, Japan. PM2.5 samples were collected at 14 sites during four campaigns. Chemical analyses of carbonaceous compounds, ionic species, and elements were conducted. Source apportionment was performed by using Positive Matrix Factorization (PMF, EPA PMF 3.0) and Chemical Mass Balance (CMB, EPA CMB 8.1) models. PMF model resolved a six-factor solution. Each of these factors has a distinctive grouping of species that can be associated with a specific source sector (F1: Biomass burning, F2: Sulfate + Oil combustion, F3: Industry, F4: Nitrate, F5: Sulfate + Coal combustion, and F6: Chloride). In the winter campaign (Jan. 24 to Feb. 7) in 2013, F5 accounted for 50% of total PM2.5 mass at Tsushima (34.2°N 129.3°E, the westernmost remote site). The contribution of F5 tended to decrease toward the eastern sites (27% at Fukuoka (33.5°N 130.5°E, urban site), 22% at Higashi-Osaka (34.7°N 135.6°E, urban site)). CMB model showed similar results in the same campaign. Coal combustion accounted for 49%, 30%, and 22% of total PM2.5 mass at Tsushima, Fukuoka, and Higashi-Osaka, respectively (Fig.1). On the other hand, at urban sites, higher contributions from local sources such as secondary nitrate (16% at Fukuoka, 21% at Higashi-Osaka), diesel fuel

  17. A comparison between aerosol properties and air pollutants

    NASA Astrophysics Data System (ADS)

    Mukai, S.; Sano, I.; Nishimori, A.; Sato, M.

    A comparison between aerosol properties and air pollutants over urban cities in Japan S. Mukai, I. Sano, A. Nishimori and M. Sato Kinki University For understanding urban aerosols, sun/sky photometry and polarimetry with PSR-1000 (Opto. Research) have been undertaken over Higashi-Osaka since 1996. Multi-spectral photometers CE-318 (Cimel Electronique) and POM-100P (Prede Co.) are set up later for an AERONET site and a SKYNET site, respectively. Radiometers provide us with the optical thickness of aerosols and Ångström exponent. Another aerosol properties, e.g., size distribution, refractive index, etc., are retrieved based on the inversion method. Higashi-Osaka, which means east side of Osaka, is an industrial city located between Osaka bay and Mt.Ikoma. Anthropogenic aerosols produced by industrial activity and oceanic aerosols flying from Osaka bay are mixed together and trapped just around our site due to reflection from Mt.Ikoma. Therefore our city is famous for heavy air pollution, and aerosols here have a complicated feature mixing with the anthropogenic compound and natural one externally and/or internally. On the other hand, suspended particles matter (SPM) concentrations at ground level are compiled for these 10 years in this city. Strictly speaking, it is difficult to relate SPM data directly to the aerosol properties, however it is possible to say that SPM data represents the mass concentration of atmospheric particles at ground level. In other word, air pollutants could have some relations to the emission and transportation of aerosols. After several aerosol parameters are derived from the measurements and compared with the SPM data, the HYSPLIT4 backward trajectory analysis is adopted to search the origin of atmospheric particles. It is found that aerosol index shows a proportional correlation with SPM concentration, and that our aerosols are contaminated not only by surroundings but also the large scale phenomena, e.g. yellow sand event from China

  18. PREFACE: International Conference on Advanced Structural and Functional Materials Design 2008

    NASA Astrophysics Data System (ADS)

    Kakeshita, Tomoyuki

    2009-07-01

    related research topics. The organizing committee gratefully thanks participants for presenting their recent results and for discussions with our COE members and international attendees. November 2008 Professor Tomoyuki Kakeshita Chairman of the Conference Vice Dean, Graduate School of Engineering, Osaka University, Division of Materials and Manufacturing Science, Graduate School of Engineering Leader of Global COE Program, Osaka University, ''Center of Excellence for Advanced Structural and Functional Materials Design'' Organization Chairman: T Kakeshita (Osaka University) Advisory Board:H Mehrer (University Münster, Germany), E K H Salje (University of Cambridge, United Kingdom), H-E Schaefer (University of Stuttgart, Germany), P Veyssiere (CNRS-ONERA, France) Organizing Committee: T Kakeshita, H Araki, H Fujii, S Fujimoto, Y Fujiwara, A Hirose, S Kirihara, M Mochizuki, H Mori, T Nagase, H Nakajima, T Nakano, R Nakatani, K Nogi, Y Setsuhara, Y Shiratsuchi, T Tanaka, T Terai, H Tsuchiya, N Tsuji, H Utsunomiya, H Yasuda, H Yasuda (Osaka University) Executive Committee: T Kakeshita, S Fujimoto, Y Fujiwara, A Hirose, T Tanaka, H Yasuda (Osaka University) Conference Secretariat: Y Fujiwara (Osaka University) Proceedings Editors: T Kakeshita and Y Fujiwara (Osaka University) Conference photograph

  19. [Tuberculosis control of urban areas in Japan].

    PubMed

    2000-10-01

    The rates of tuberculosis remain high in urban areas. The declining speed of tuberculosis incidence rate in urban areas has been slower than other areas. Efforts and resources to tuberculosis control must be concentrated on urban locations to eradicate tuberculosis in Japan. 1. Tuberculosis control in a public health center of urban area: Teru OGURA and Chiyo INOGUCHI (Toshima City, Ikebukuro Public Health Center, Tokyo Metropolitan) A wide range of TB control measures is implemented by public health centers, such as a patient registration, home-visit guidance, contact examination in urban areas. Directors of every health center have the direct responsibility for tuberculosis control measures in their jurisdiction. Ikebukuro is urban areas where there are many offices, shopping and amusement facilities. Urban people is often on the move looking for job, so public health centers are often not easy to carry out contact examinations as planned. In recent years, homelessness has been recognized as a growing urban social problem. Their incidence of tuberculosis is high. Special TB control program must be carried out in urban areas. 2. Tuberculosis Control in Tokyo Metropolitan: Kazumasa MATSUKI (Department of Infectious Diseases and Tuberculosis, Bureau of Public Health, Tokyo Metropolitan) There has been a steady decline in the TB wards. The beds for TB patients are running short and even smear positive TB cases cannot be put in a hospital without waiting several days. Staffs of an urban emergency department must protect tuberculosis infection by environmental controls of emergency room. Tokyo Metropolitan government supports the engineering improvements of emergency room to hospitals. Directly observed therapy for tuberculosis patients at a district has been implemented to complete their therapy. On DOT, a trained health worker observes the patient take anti-TB medication. 3. Usefulness of Molecular Epidemiologic approach on Tuberculosis Control: Atsushi HASE (Osaka

  20. Serum Uric Acid Level Predicts Progression of IgA Nephropathy in Females but Not in Males

    PubMed Central

    Shoji, Tatsuya; Shinzawa, Maki; Hasuike, Yukiko; Nagatoya, Katsuyuki; Yamauchi, Atsushi; Hayashi, Terumasa; Kuragano, Takayuki; Moriyama, Toshiki; Isaka, Yoshitaka; Nakanishi, Takeshi

    2016-01-01

    Background Immunoglobulin A nephropathy (IgAN) is one of most common forms of glomerulonephritis. At this point, the clinical impact of hyperuricemia on IgAN is not clear. The aim of the present study was to explore the clinical impact of hyperuricemia on the progression of IgAN. Study Design Multicenter retrospective cohort study. Setting & Participants 935 IgAN patients who were diagnosed by kidney biopsy at Osaka University Hospital, Osaka General Hospital, and Osaka Rosai Hospital. were included in this study. Predictor Uric acid levels at renal biopsy. Outcomes The outcome of interest was the time from the kidney biopsy to the time when a 50% increase in the baseline serum creatinine level was observed, which was defined as "progression". Measurements The baseline characteristics according to the kidney biopsy at the time of diagnosis were collected from the medical records, and included age, gender, body mass index, hypertension, diabetes (use of antidiabetic drugs), serum levels of creatinine, urinary protein, smoking status, RAAS blockers and steroid therapy. Results An elevated serum uric acid level was an independent risk factor for progression in female patients (per 1.0 mg/dL, multivariate-adjusted incident rate ratio 1.33 [95% confidence interval 1.07, 1.64], P = 0.008) but not in male patients (1.02 [0.81, 1.29], P = 0.855). To control a confounding effect of renal function on an association between serum uric acid level and progression in female patients, age- and serum creatinine-matched and propensity score-matched analyses were performed, and these results also supported the effect by uric acid on kidney disease progression independent of basal kidney function. Limitations A cohort analyzed retorospectively. Conclusions This study revealed that an elevated uric acid level was an independent risk factor for ESKD in female IgAN patients. Therefore, uric acid might be a treatable target in female IgAN patients. PMID:27560997

  1. Long Period Ground Motion Prediction Of Linked Tonankai And Nankai Subduction Earthquakes Using 3D Finite Difference Method

    NASA Astrophysics Data System (ADS)

    Kawabe, H.; Kamae, K.

    2005-12-01

    There is high possibility of the occurrence of the Tonankai and Nankai earthquakes which are capable of causing immense damage. During these huge earthquakes, long period ground motions may strike mega-cities Osaka and Nagoya located inside the Osaka and Nobi basins in which there are many long period and low damping structures (such as tall buildings and oil tanks). It is very important for the earthquake disaster mitigation to predict long period strong ground motions of the future Tonankai and Nankai earthquakes that are capable of exciting long-period strong ground motions over a wide area. In this study, we tried to predict long-period ground motions of the future Tonankai and Nankai earthquakes using 3D finite difference method. We construct a three-dimensional underground structure model including not only the basins but also propagation field from the source to the basins. Resultantly, we can point out that the predominant periods of pseudo-velocity response spectra change basin by basin. Long period ground motions with periods of 5 to 8 second are predominant in the Osaka basin, 3 to 6 second in the Nobi basin and 2 to 5 second in the Kyoto basin. These characteristics of the long-period ground motions are related with the thicknesses of the sediments of the basins. The duration of long period ground motions inside the basin are more than 5 minutes. These results are very useful for the earthquake disaster mitigation of long period structures such as tall buildings and oil tanks.

  2. Development of adaptive phonetic gestures in children: evidence from vowel devoicing in two different dialects of Japanese.

    PubMed

    Imaizumi, S; Fuwa, K; Hosoi, H

    1999-08-01

    High vowels between voiceless consonants are often devoiced in many languages, as well as in many dialects of Japanese. This phenomenon can be hypothesized to be a consequence of the adaptive organization of the laryngeal gestures to various conditions, including dialectal requirements. If this theory is correct, it may be possible to predict developmental changes in vowel devoicing based on the developmental improvement in the dialect-specific organization of the laryngeal gestures. To test this expectation, the developmental properties of vowel devoicing were investigated for 72 children of 4 and 5 years of age, and 37 adults in two dialects of Japanese. One was the Osaka dialect, with a low devoicing rate, and the other the Tokyo dialect, with a high devoicing rate. In the Tokyo dialect, the devoicing rate of children significantly increased and reached an adultlike level by the age of 5 years, whereas it remained low irrespective of age in Osaka. The vowel devoicing of 5-year-old children exhibited the same characteristics as that of the adults of their respective dialect. These results suggest that children growing up with the Tokyo dialect acquire the articulatory gestures which do not inhibit vowel devoicing by the age of 5 years, whereas children growing up with the Osaka dialect acquire those which inhibit the devoicing of vowels by the same age. The results fit in well with the predictions of the gestural account of vowel devoicing. It is also suggested that learning dialect-specific adaptive strategies to coordinate voicing and devoicing gestures as required to attain an adultlike vowel devoicing pattern is a long process: By the age of 5 years children have completed enough of this process to become members of their dialectal community.

  3. Levels of perfluorooctane sulfonate and perfluorooctanoic acid in female serum samples from Japan in 2008, Korea in 1994-2008 and Vietnam in 2007-2008.

    PubMed

    Harada, Kouji H; Yang, Hye-Ran; Moon, Chan-Seok; Hung, Nguyen Ngoc; Hitomi, Toshiaki; Inoue, Kayoko; Niisoe, Tamon; Watanabe, Takao; Kamiyama, Shigetoshi; Takenaka, Katsunobu; Kim, Min-Young; Watanabe, Kiyohiko; Takasuga, Takumi; Koizumi, Akio

    2010-04-01

    Perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) have recently received attention owing to their widespread contamination in the environment. One of major manufacturers, 3M Company voluntarily phased out PFOS production in 2002. We measured the PFOS and PFOA concentrations in serum samples from Japan (Sendai, Takayama and Osaka), Korea (Busan and Seoul) and Vietnam (Hanoi) to evaluate the possible effects of the phase-out on the serum levels. There were spatial differences in both the serum PFOS and PFOA concentrations. The serum PFOS concentrations (ngmL(-1)) evaluated as the geometric mean (geometric standard deviation) in 2007-2008 ranged from 4.86 (1.45) in Sendai, Japan, to 9.36 (1.42) in Busan, Korea. The serum PFOA concentrations ranged from 0.575 (2.32) in Hanoi, Vietnam, to 14.2 (1.73) in Osaka, Japan. Historically archived samples collected from Korea in 1994-2008 revealed that the serum PFOA concentrations increased by 1.24-fold in Busan from 2000 to 2008 and 1.41-fold in Seoul from 1994 to 2007. On the other hand, the serum PFOS concentrations did not change from 1994 to 2007/2008. The serum PFOS levels in Japan in 2008 were significantly decreased compared with previously reported values (22.3-66.7% of the values in 2003/2004). However, the serum PFOA levels showed a clear decline from 2003 to 2008 in a high-exposed area, Osaka, but not in low-exposed areas in Japan. The trends toward decreases were not uniformly observed in Asian countries, unlike the case for the United States, suggesting that local factors associated with the production and introduction histories in each country overwhelm the effects of the phase-out. 2010 Elsevier Ltd. All rights reserved.

  4. PREFACE: Fourth International Symposium on Atomic Technology

    NASA Astrophysics Data System (ADS)

    Okada, Shigefumi

    2010-04-01

    The International Symposium on Atomic Technology (ISAT) is held every year. The 4th Symposium (ISAT-4) was held on November 18-19, 2009 at the Seaside Hotel MAIKO VILLA KOBE, Kobe City, Japan presided by the "Atomic Technology Project". The ISAT-4 symposium was intended to offer a forum for the discussion on the latest progress in the atomic technologies. The symposium was attended by 107 delegates. There were 10 invited and 6 oral presentations. The number of poster presentations was 69. From all the contributions, 22 papers selected through review process are contained in this volume. The "Atomic Technology Project" was started in 2006 as a joint project of three institutions; (1) the Center for Atomic and Molecular Technologies, Graduate School of Engineering, Osaka University (CAMT), (2) the Tsukuba Research Center for Interdisciplinary Materials Science, Graduate School of Pure and Applied Sciences, University of Tsukuba (TIMS) and (3) the Polyscale Technology Research Center, Research Institute for Science and Technology, Tokyo University of Science (PTRC), each of which were independently pursuing nano-technologies and was developing atomic scale operation and diagnostics, functional materials, micro processing and device. The project is funded by the Ministry of Education, Culture, Sports, Science and Technology of Japan. The goal of the project is to contribute to the development of atomic-scale science and technologies such as functional molecules, biomaterials, and quantum functions of atomic-scale structures. Shigefumi Okada Conference Chair Center for Atomic and Molecular Technologies, Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita-city, Osaka 565-0871, Japan. Conference photograph Kobe photograph

  5. Comparison study of Lightning VHF interferometric and LF time-of-arival maps

    NASA Astrophysics Data System (ADS)

    Kudo, A.; Stock, M.; Kawasaki, Z.; Ushio, T.

    2016-12-01

    Lightning discharges radiate broad band frequency electromagnetic waves from ULF to UHF. Using sensors which detect this radiation is an effective technique to detect lightning flashes, even if they are in a cloud. If multiple sensors are present, a lightning flash can be located using various techniques. At low frequencies, the power radiated by lightning is very high, but because the wavelengths are long, the location resolution is somewhat low. At very high frequencies, the wavelengths are much shorter allowing for much better location resolution, but the power radiation is also much lower, making it more difficult to detect. The VHF band is a good compromise between good location resolution, and good detection efficiency. One technique to locate VHF signals from lightning is interferometry. Using this technique, the signals arriving at three or more VHF broadband antennas are coherently combined to produce an image of the lightning flash. The current generation broadband lightning interferometer being developed in Japan by RAIRAN and the University of Osaka called Lightning Interferometer via VHF Emission (LIVE). Currently, LIVE is installed in Kaizuka, a city to the south of Osaka, near Osaka Bay to observe Japanese summer lightning. In the current study, we are comparing the high detail, 2-dimensional lightning maps produced by LIVE to the lower detail, 3-dimensional maps produced by a low frequency time-of-arrival system called the Broadband Observation network for Lightning and Thunderstorms (BOLT). In order to better compare the data, a new GPS timing device is being developed for LIVE to allow high absolute timing accuracy without sacrificing one of the 4 high speed digitizer channels. The objectives of the study are to better understand Japanese summer lightning, and to prepare for a future campaign as part of the GLM validation study.

  6. PREFACE: The International Symposium on Atomic Technology

    NASA Astrophysics Data System (ADS)

    Shirai, Yasuharu

    2008-03-01

    The International Symposium on Atomic Technology (ISAT) is held every year. The Second Symposium (ISAT-2) was held on 1-2 October 2007 at the Awaji Yumebutai Conference Center, Awaji City, Japan presided by the `Atomic Technology Project'. The ISAT-2 symposium was intended to offer a forum for the discussion of the latest progress in atomic technologies. The symposium was attended by 106 delegates. There were 9 invited and 5 oral presentations. The number of poster presentations was 73. From all the contributions, 24 papers selected through review process are contained in this volume. The `Atomic Technology Project' was started in 2006 as a joint project of three institutions; (1) Center for Atomic and Molecular Technologies, Graduate School of Engineering, Osaka University (CAMT), (2) Tsukuba Research Center for Interdisciplinary Materials Science, Graduate School of Pure and Applied Sciences, University of Tsukuba (TIMS) and (3) Polyscale Technology Research Center, Research Institute for Science and Technology, Tokyo University of Science (PTRC), each of which were independently pursuing nano-technologies and were developing atomic scale operation and diagnostics, functional materials, micro processing and devices. The project is funded by the Ministry of Education, Culture, Sports, Science and Technology of Japan. The goal of the project is to contribute to the development of atomic-scale science and technologies such as functional molecules, biomaterials, and quantum functions of atomic-scale structures. Yasuharu Shirai Conference Chair Center for Atomic Technologies, Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita-city, Osaka 565-0871, Japan. Conference photograph

  7. Studying the stars on earth: astrophysics on intense lasers

    SciTech Connect

    Remington, B A

    1999-03-10

    Lawrence Livermore National Laboratory in Livermore, California, is now performing significant astrophysics experiments on its huge Nova laser facility, and a similar effort has started at the Gekko laser facility at Osaka University in Japan. Our experiments on the Nova and Gekko lasers so far encourage us that our astrophysics work is already leading to a better understanding of the hydrodynamics of supernovae and astrophysical jets. The ability of large inertial confinement fusion lasers to recreate star-like conditions in the laboratory greatly improves our understanding of the heavens; for the first time in our history, we can study the stars up close on Earth.

  8. Committees and supporting organizations

    NASA Astrophysics Data System (ADS)

    2011-09-01

    Advisory Committee:Organizing Committee: Marcello Baldo (Catania)Takaharu Otsuka (Tokyo), co-chair George Bertsch (Seattle)Michael Urban (Orsay), co-chair Jean-Paul Blaizot (Saclay)Taiichi Yamada (Yokohama) Michel Girod (Bruyères-le-Châtel)Nguyen van Giai (Orsay) Hisashi Horiuchi (Osaka)Shinichiro Fujii (Tokyo) Umberto Lombardo (Catania)Jérôme Margueron (Orsay) Gerd Röpke (Rostock)Kouichi Hagino (Sendai) Hiroyuki Sagawa (Aizu)Yoshiko Kanada-En'yo (Kyoto) Piet Van Isacker (Caen) Enrico Vigezzi (Milano) IPN logo    EFES logo    CNRS logo    ihp logo

  9. Converging shock generation with cone target filled with low density foam

    NASA Astrophysics Data System (ADS)

    Shigemori, K.; Yamamoto, T.; Hironaka, Y.; Kawashima, T.; Hattori, S.; Nagatomo, H.; Kato, H.; Sato, N.; Watari, T.; Takagi, M.

    2016-05-01

    We have been developing an alternative scheme of fast ignition of inertial confinement targets with converging shock. Experiments were carried out on GEKKO-XII laser facility at ILE, Osaka University. We employed Au cone targets filled with low- density RF foam (2 mg/cm3). The foam-filled cone targets were irradiated by three beams of the GEKKO-XII, with pulse duration of 1.3 ns, intensity of ∼ 1014 W/cm2 in 2 :λ(ω0.527μm). Self-emission at the tip of cone was observed by one-dimensional streaked optical pyrometer (SOP) and two-dimensional images.

  10. Urbanization and subsurface environmental issues: an attempt at DPSIR model application in Asian cities.

    PubMed

    Jago-on, Karen Ann Bianet; Kaneko, Shinji; Fujikura, Ryo; Fujiwara, Akimasa; Imai, Tsuyoshi; Matsumoto, Toru; Zhang, Junyi; Tanikawa, Hiroki; Tanaka, Katsuya; Lee, Backjin; Taniguchi, Makoto

    2009-04-15

    This paper synthesizes existing information and knowledge on subsurface environments to understand the major cause and effect relationships of subsurface environmental issues by using the DPSIR (Driving force-Pressure-Status-Impact-Response) approach as the framework of analysis. Description is given to the major subsurface environmental issues common among the selected Asian cities (Bangkok, Jakarta, Manila, Osaka, Seoul, Taipei and Tokyo), such as excessive groundwater abstraction, land subsidence and groundwater contamination. The DPSIR framework is used to analyze the issues and problems of subsurface in key stages and suggestions are made for additional indicators to improve our description of the stages of urban development for the future.

  11. Disturbed mouse circadian rhythm before the Kobe EQ in 1995

    NASA Astrophysics Data System (ADS)

    Yokoi, Sayoko

    2013-04-01

    Legends of macro-anomalies before large earthquakes have been passed down for generations in Asia. Most of the statements on earthquake precursors are considered unreliable afterthoughts by traditional scientists. However, disturbed biological rhythms in mice were observed before the Kobe EQ in 1995 (Yokoi et al, 2003). The records of unusual mouse behavior before the earthquake were obtained to study biological clock at Institute for Protein Research, Osaka University. It is clarified that the disturbance was very rare phenomena statistically. Similar phenomenon was observed before the Wenchuan earthquake in 2008, too (Li et al, 2009). In the presentation, I will discuss the phenomena as one example of preseismic unusual animal behaviors.

  12. Highlighting the History of Japanese Radio Astronomy: 1: An Introduction

    NASA Astrophysics Data System (ADS)

    Ishiguro, Masato; Orchiston, Wayne; Akabane, Kenji; Kaifu, Norio; Hayashi, Masa; Nakamura, Tsuko; Stewart, Ronald; Yokoo, Hiromitsu

    2012-11-01

    Japan was one of a number of nations that made important contributions in the fledgling field of radio astronomy in the years immediately following WWII. In this paper we discuss the invention of the Yagi-Uda antenna and the detection of solar radio emission in 1938, before reviewing radio astronomical developments that occurred between 1948 and 1961 in Osaka, Nagoya, Tokyo and Hiraiso. In order to place these early Japanese experiments in a national and international context we briefly review the world-wide development of radio astronomy in the immediate post-War years before discussing the growth of optical astronomy in Japan at this time.

  13. Holocene relative sea-level change in Hiroshima Bay, Japan: A semi-quantitative reconstruction based on ostracodes

    USGS Publications Warehouse

    Yasuhara, Moriaki; Seto, Koji

    2006-01-01

    Holocene relative sea-level changes in Hiroshima Bay were reconstructed from fossil ostracodes from a core, using a semi-quantitative method. In Hiroshima Bay, relative sea level rose rapidly (about 25 m) between ca. 9000 cal yr BP and ca. 5800 cal yr BP, after which it gradually fell (about 5 m) to its present level. The peak in relative sea level occurred at ca. 5800 cal yr BP. The sea-level curve for Hiroshima Bay is similar to curves for tectonically stable areas of Japan (e.g., Osaka Bay). ?? by the Palaeontological Society of Japan.

  14. Nuclear quadrupole resonance spectra database

    NASA Astrophysics Data System (ADS)

    Chihara, H.

    A computer-readable file of numerical data of nuclear quadrupole resonance frequency is being built which also serves as a bibliographic file. The data are compiled by reviewing original papers, reprints, and published data books and retrieving such data elements as substance names, nuclear mass number, temperature of measurements, resonance frequencies, nuclear quadrupole coupling constants, asymmetry parameters, and keywords. The database contains, if available, CAS registry number, molecular formulas and systematic names, and other synonyms of chemical substances. About 800 records have been loaded for online, TSS search through the Computer Center of Osaka University.

  15. Effect of a stable prostacyclin analogue on canine renal allograft rejection.

    PubMed Central

    Tobimatsu, M; Ueda, Y; Toyoda, K; Saito, S; Konomi, K

    1987-01-01

    The effect of OP-41483 (Ono Pharmaceutical Co., Osaka, Japan), a stable prostacyclin analogue, on canine renal allograft rejection was investigated. Administration for 4 days after transplantation significantly increased renal cortical blood flow and urine output when compared with untreated dogs with renal allografts. Serum creatinine levels remained relatively low during postoperative days 1-4. Mean animal survival time was prolonged. Vascular lesions and mononuclear cell infiltration were greatly diminished in biopsy specimens removed on day 4. This stable prostacyclin analogue provided a degree of protection against canine renal allograft rejection. Images Figs. 1A and B. PMID:3545109

  16. High Repetition Rate Electron Beam RF-Acceleration and Sub-Millimeter Wave Generation Via a Free Electron Laser.

    DTIC Science & Technology

    1987-08-14

    D.S. Furuno, N.C. Luhmann, Jr., W.J. Nunan , Haibo Cao, "Compact, High Power Millimeter Wave Sources," Proc. of Sixth Int. Conf. High Power Particle...Beams, Osaka, Japan (1986). (b) D.B. McDermott, W.J. Nunan and N.C. Luhmann, Jr., "A Prebunched 94 GHz Free Electron Laser," Proc. of the Eleventh IEEE...Int. Conf. IR and mm-Waves, Pisa, Italy (1986). (c) W.J. Nunan , D.B. McDermott and N.C. Luhmann, Jr., "A High Duty Cycle, Compact 94 GHz FEL," Bull

  17. Star formation in Taurus Auriga Perseus and California nebulae

    NASA Astrophysics Data System (ADS)

    Tóth, L. Viktor; Zahorecz, Sarolta; Marton, Gabor; Doi, Yasuo; Onishi, Toshikazu; Tokuda, Kazuki

    Star formation and interstellar medium (ISM) structure were investigated in the Taurus, Auriga, Perseus and California (TAP) nearby star forming regions. Properties of the cold ISM was derived using AKARI FIR all sky maps, the Osaka-1.85m CO survey focusing to the all-sky Planck catalogue of Galactic Cold Clumps (PGCC). As many as 1041 infrared point sources were classified as young stellar object (YSO) based on multiband photometric data, and 384 of those are associated to a PGCC object. About 30% of the TAP PGCC clumps have associated YSOs.

  18. Incidence of otitis externa in dogs and cats in Japan.

    PubMed

    Baba, E; Fukata, T

    1981-05-02

    The incidence of otitis externa in dogs and cats admitted to the animal hospital of the University of Osaka Prefecture was investigated and the bacteria isolated were tested for antibiotic susceptibility. Of the various breeds examined, the incidence of otitis externa was highest in miniature poodles and cocker spaniels and Himalayan and Persian cats. The organisms most commonly associated with otitis externa were coagulase-negative staphylococci, followed by coagulase-positive staphylococci, streptococci and Escherichia coli. Most staphylococci were susceptible to the antibiotics tested, but 15 per cent of staphylococci were resistant to more than three antibiotics. Pseudomonas and Alcaligenes species were resistant to almost all antibiotics except gentamicin and colistin.

  19. Performance testing of the neutron flux monitors from 10keV to 1MeV developed for BNCT: A preliminary study.

    PubMed

    Guan, Xingcai; Manabe, Masanobu; Tamaki, Shingo; Sato, Fuminobu; Murata, Isao; Wang, Tieshan

    2017-07-01

    The neutron flux monitors from 10keV to 1MeV designed for boron neutron capture therapy (BNCT) were experimentally tested with prototype monitors in an appropriate neutron field produced at the intense deuterium-tritium neutron source facility OKTAVIAN of Osaka University, Japan. The experimental test results and related analysis indicated that the performance of the monitors was good and the neutron fluxes from 10keV to 1MeV of practical BNCT neutron sources can be measured within 10% by the monitors. Copyright © 2017 Elsevier Ltd. All rights reserved.

  20. Simultaneous Stabilization of Gyrotron Frequency and Power by PID Double Feedback Control on the Acceleration and Anode Voltages

    NASA Astrophysics Data System (ADS)

    Khutoryan, E. M.; Idehara, T.; Kuleshov, A. N.; Tatematsu, Y.; Yamaguchi, Y.; Matsuki, Y.; Fujiwara, T.

    2017-03-01

    In this paper, we present the results of simultaneous stabilization of both the frequency and the output power by a double PID feedback control on the acceleration and anode voltages in the 460-GHz gyrotron FU CW GVI, also known as "Gyrotron FU CW GO-1" (according to the nomenclature adopted at Osaka University). The approach used in the experiments is based on the modulation of the cyclotron frequency and the pitch factor (velocity ratio) of the electron beam by varying the acceleration and the anode voltages, respectively. In a long-term experiment, the frequency and power stabilities were made to be better than ±10-6 and ±1%, respectively.

  1. Topical Meeting on Optical Bistability Held at Rochester, New York on 15-17 June 1983.

    DTIC Science & Technology

    1983-01-01

    ThB16-1 SELF-BEATING INSTABILITIES IN BISTABLE DEVICES J.A. MARTIN-PEREDA .. M.A. MURIEL DEPARTAMENTO DE ELECTRONICA CUANTICA E.T.S. ING...OPTICAL BISTABLL SYSTEMS J.A. MARTIN PEREDA M.A. MURIEL ; DEPARTAMENIO DE ELECTRONICA CUANTICA E.T.S. ING. TELLCOMUNICACION UNIVERSIDAD POLITECNICA DE...Permanent address: The Institute of Scientific and Industrial Research, S University, Yamadakami, Suita, Osaka 565, Japan 0loo ThB40-1 SELFPULSINGS

  2. Development of an L-Band RF Electron Gun for SASE in the Infrared Region

    NASA Astrophysics Data System (ADS)

    Kashiwagi, Shigeru; Kato, Ryukou; Isoyama, Goro; Hayano, Hitoshi; Urakawa, Junji

    2010-02-01

    We conduct research on Self-Amplified Spontaneous Emission (SASE) in the infrared region using the 40 MeV, 1.3 GHz L-band linac of Osaka University. The linac equipped with a thermionic electron gun can accelerate a high-intensity single-bunch beam though its normalized emittance is high. In order to advance the research on SASE, we have begun development of an RF gun for the L-band linac in collaboration with KEK. We will report conceptual design of the RF gun and present the status of development of another RF gun for STF at KEK.

  3. Adaptive Optics for Industry and Medicine International Workshop.

    DTIC Science & Technology

    1998-01-07

    81-6-877-0900, e-mail: yoon@ile.osaka-u.ac.jp. 17. Victor I. Shmalhausen, International Laser Center, Moscow State University, Vorob’evy Gory,t 119899... Manuel Toledo- Quinones 3 Adaptive Optics Associates 54 CambridgePark Drive 3 Cambridge, MA 02140 (617)864-0201 (voice) * (617)864-1348 (fax) marty...maximum value) I LSE References: ST. Luna , "Linear Stochastic Estimation of Optical Beam Deflection through a Heated Round Turbulent Jet," MS Thesis

  4. Performance of Lithium Ion Cell Anode Graphites Under Various Cycling Conditions

    SciTech Connect

    Ridgway, Paul; Zheng, Honghe; Liu, Gao; Song, Xiangun; Guerfi, Abdelbast; Charest, Patrick; Zaghib, Karim; Battaglia, Vincent

    2009-06-15

    Graphites MCMB-2810 and OMAC-15 (made by Osaka Gas Inc.), and SNG12 (Hydro Quebec, Inc.) were evaluated (in coin cells with lithium counter electrodes) as anode materials for lithium-ion cells intended for use in hybrid electric vehicles. Though the reversible capacity obtained for SNG was slightly higher than that of OMAC or MCMB, its 1st cycle efficiency was lower. Voltage vs capacity plots of cycling data show that the discharge and charge limits shift to higher capacity values due to continuation of anode side reactions. Varying the cycle charge and discharge limits was found to have no significant effect on fractional capacity shift per cycle.

  5. Draft genome sequence of Halomonas sp. strain KM-1, a moderately halophilic bacterium that produces the bioplastic poly(3-hydroxybutyrate).

    PubMed

    Kawata, Yoshikazu; Kawasaki, Kazunori; Shigeri, Yasushi

    2012-05-01

    We report the draft genome sequence of Halomonas sp. strain KM-1, which was isolated in Ikeda City, Osaka, Japan, and which produces the bioplastic poly(3-hydroxybutyrate). The total length of the assembled genome is 4,992,811 bp, and 4,220 coding sequences were predicted within the genome. Genes encoding proteins that are involved in the production and depolymerization of poly(3-hydroxybutyrate) were identified. The identification of these genes might be of use in the production of the bioplastic poly(3-hydroxybutyrate) and its monomer 3-hydroxybutyrate.

  6. A review of recent fusion neutronics experiments

    SciTech Connect

    Maekawa, Hiroshi; Oyama, Yukio; Ikeda, Yujiro

    1994-12-31

    This paper reviews experimental activities in fusion neutronics experiments since the last International Conference on Nuclear Data. Many experiments have been carried out in Japan at FNS/JAERI, OKTAVIAN /Osaka University and KURRI/Kyoto University. Experiments on Be were performed at INEL/USA, KfK/FRG, SINPC/PRC, OKTAVIAN/Japan and several institutes in CIS, Czech Republic and Ukraine. A new series of shielding experiments have been started at FNS, ENEA/Frascati, TUD and Russian institutes for ITER/EDA R&D program.

  7. Snow on cholera--the special lecture in the Second British Epidemiology and Public Health Course at Kansai Systems Laboratory on 24 August 1996.

    PubMed

    Tanihara, S; Morioka, S; Kodama, K; Hashimoto, T; Yanagawa, H; Holland, W W

    1998-10-01

    The Second British Epidemiology and Public Health Course was held from 19 to 25 August 1996 in Osaka as a satellite meeting for the 14th International Scientific Meeting of the International Epidemiological Association. Thirty-three researchers from 10 countries participated in the course. Professor Walter W Holland gave a special lecture about Snow on cholera during the course, and the lecture revealed that Henry Whitehead who was a junior priest at that time contributed to Snow's work to prevent the cholera outbreak in Golden Square in 1854. What John Snow did in his life are reviewed in detail in this paper.

  8. Simultaneous Stabilization of Gyrotron Frequency and Power by PID Double Feedback Control on the Acceleration and Anode Voltages

    NASA Astrophysics Data System (ADS)

    Khutoryan, E. M.; Idehara, T.; Kuleshov, A. N.; Tatematsu, Y.; Yamaguchi, Y.; Matsuki, Y.; Fujiwara, T.

    2017-07-01

    In this paper, we present the results of simultaneous stabilization of both the frequency and the output power by a double PID feedback control on the acceleration and anode voltages in the 460-GHz gyrotron FU CW GVI, also known as "Gyrotron FU CW GO-1" (according to the nomenclature adopted at Osaka University). The approach used in the experiments is based on the modulation of the cyclotron frequency and the pitch factor (velocity ratio) of the electron beam by varying the acceleration and the anode voltages, respectively. In a long-term experiment, the frequency and power stabilities were made to be better than ±10-6 and ±1%, respectively.

  9. Dipole Magnet for Beam Line Switching

    NASA Astrophysics Data System (ADS)

    Yoshida, Jun

    We are developing a Bi-2223 HTS dipole magnet for beam line switching for use in the cyclotron facility of RCNP, Osaka University. Exit beam lines are periodically switched by increasing and decreasing of the magnetic field between 0 T and 1.6 T with a switching time of 10 sec. A Bi-2223 coil assembly was designed with the electromagnetic force support and the suppression of temperature rise by AC loss and eddy current loss. In this chapter, we introduce this magnet as a practical example of conduction-cooled Bi-2223-HTS magnet for accelerator application.

  10. Spin-Ml and El responses of nuclei probed by proton inelastic scattering

    NASA Astrophysics Data System (ADS)

    Tamii, Atsushi; Matsubara, Hiroaki

    2014-12-01

    We pick up two studies on the nuclear responses from the recent experiments of high-resolution proton inelastic scattering at the Research Center for Nuclear Physics, Osaka University; 1) study of the nuclear symmetry and the neutron skin thickness by the measurement of energy electric dipole (El) response of 208Pb, and 2) study of the tensor correlation in the ground state by the measurement of the spin-Ml responses of even-even self-conjugate nuclei in the sd-shell nuclei.

  11. Development and Observation of the Phase Array Radar at X band

    NASA Astrophysics Data System (ADS)

    Ushio, T.; Shimamura, S.; Wu, T.; Kikuchi, H.; Yoshida, S.; Kawasaki, Z.; Mizutani, F.; Wada, M.; Satoh, S.; Iguchi, T.

    2013-12-01

    A new Phased Array Radar (PAR) system for thunderstorm observation has been developed by Toshiba Corporation and Osaka University under a grant of NICT, and installed in Osaka University, Japan last year. It is now well known that rapidly evolving severe weather phenomena (e.g., microbursts, severe thunderstorms, tornadoes) are a threat to our lives particularly in a densely populated area and is closely related to the production of lightning discharges. Over the past decade, mechanically rotating radar systems at the C-band or S-band have been proved to be effective for weather surveillance especially in a wide area more than 100 km in range. However, severe thunderstorm sometimes develops rapidly on the temporal and spatial scales comparable to the resolution limit (-10 min. and -500m) of typical S-band or C-band radar systems, and cannot be fully resolved with these radar systems. In order to understand the fundamental process and dynamics of such fast changing weather phenomena like lightning and tornado producing thunderstorm, volumetric observations with both high temporal and spatial resolution are required. The phased array radar system developed has the unique capability of scanning the whole sky with 100m and 10 to 30 second resolution up to 60 km. The system adopts the digital beam forming technique for elevation scanning and mechanically rotates the array antenna in azimuth direction within 10 to 30 seconds. The radar transmits a broad beam of several degrees with 24 antenna elements and receives the back scattered signal with 128 elements digitizing at each elements. Then by digitally forming the beam in the signal processor, the fast scanning is realized. After the installation of the PAR system in Osaka University, the initial observation campaign was conducted in Osaka urban area with Ku-band Broad Band Radar (BBR) network, C-band weather radar, and lightning location system. The initial comparison with C band radar system shows that the developed

  12. The MUSIC Project

    SciTech Connect

    Yoshida, Makoto

    2010-03-30

    A new muon channel, MUSIC, is being constructed at the Research Center for Nuclear Physics (RCNP) at Osaka University in Japan. The muon channel utilizes a strong solenoidal magnetic field to collect pions and to transport muons. A large-bore superconducting coil encloses the pion-production target to capture pions with a large solid angle. A long solenoid magnet transports pions and muons with the capability to select the charge and momentum of the particles. The design of the solenoid channel is described in this paper.

  13. Development of Technologies to Utilize Laser Plasma Radiations Sources for Radiation Effects Sciences

    SciTech Connect

    Davis, J F

    2007-01-31

    This final report will cover work performed over the period of November 11, 2005 to September 30, 2006 on the contract to develop technologies using laser sources for radiation effects sciences. The report will discuss four topic areas; the laser source experiments on the Gekko Laser at Osaka, Japan, planning for the Charge State Freeze Out experiments to be performed in calendar year 2007, a review of previous xenon gasbags on the LANL Trident laser to provide planning support to the May-June 2007 HELEN experiments.

  14. Multimedia Database at National Museum of Ethnology

    NASA Astrophysics Data System (ADS)

    Sugita, Shigeharu

    This paper describes the information management system at National Museum of Ethnology, Osaka, Japan. This museum is a kind of research center for cultural anthropology, and has many computer systems such as IBM 3090, VAX11/780, Fujitu M340R, etc. With these computers, distributed multimedia databases are constructed in which not only bibliographic data but also artifact image, slide image, book page image, etc. are stored. The number of data is now about 1.3 million items. These data can be retrieved and displayed on the multimedia workstation which has several displays.

  15. [Cholangiocarcinoma among printing workers].

    PubMed

    Kumagai, Shinji

    2014-02-01

    By June 2013, seventeen workers had suffered from intrahepatic or extrahepatic bile duct cancer (cholangiocarcinoma) in an offset proof-printing company in Osaka and nine of the workers had died. Ages at diagnosis were 25 to 45 years old. Known risk factors for cholangiocarcinoma were not found in the patients. All of the patients were exposed to 1,2-dichloropropane at high level for long-term and were diagnosed with cholangiocarcinoma 7 to 20 years after the first exposure. Twelve of the patients were also exposed to dichloromethane. The Japan Ministry of Health, Labour and Welfare recognized the cancer to be an occupational disease.

  16. [Cholangiocarcinoma developing in printing company workers: a new type of occupational cancer].

    PubMed

    Kubo, Shoji; Takemura, Shigekazu; Sakata, Chikaharu; Urata, Yorihisa; Tanaka, Shogo; Nakanuma, Yasuni; Endo, Ginji

    2013-11-01

    The incidence of cholangiocarcinoma among the past or present workers in the department of offset color proof-printing at a printing company in Osaka was extremely high. The workers were relatively young and were exposed to several chemicals including organic solvents such as dichloromethane and 1,2-dichloropropane. Although the exact cause of cholangiocarcinoma in the patients remain unknown, it is likely that the development of cholangiocarcinoma was triggered during exposure to these chemicals. Some chemicals can act as environmental factors that lead to the development of cholangiocarcinoma. Therefore, we believe that cholangiocarcinoma is a new type of occupational cancer.

  17. Fine Structure of the Gamow-Teller Resonance in {sup 90}Nb and Level Density of 1{sup +} States

    SciTech Connect

    Kalmykov, Y.; Neumann-Cosel, P. von; Ponomarev, V.Yu.; Richter, A.; Shevchenko, A.; Wambach, J.; Adachi, T.; Fujita, Y.; Shimbara, Y.; Berg, G.P.A.; Fujita, K.; Hatanaka, K.; Kamiya, J.; Nakanishi, K.; Sakamoto, N.; Sakemi, Y.; Shimizu, Y.; Wakasa, T.; Fujita, H.; Smit, F.D.

    2006-01-13

    The fine structure of the Gamow-Teller resonance in a medium-heavy nucleus is observed for the first time in a high-resolution {sup 90}Zr({sup 3}He,t){sup 90}Nb experiment at the Research Center for Nuclear Physics, Osaka. Using a novel wavelet analysis technique, it is possible to extract characteristic energy scales and to quantify their relative importance for the generation of the fine structure. This method combined with the selectivity of the reaction permits an extraction of the level density of 1{sup +} states in {sup 90}Nb.

  18. Tuberculous Fasciitis in Polymyositis: A Rare Case of Extrapulmonary Tuberculosis

    PubMed Central

    Nagayama, Ikue; Nagatoya, Katsuyuki; Kurahara, Yu; Mega, Akira; Morita, Masashi; Haga, Ryota; Yamanouchi, Yu; Yamaguchi, Yoshito; Oka, Tatsufumi; Yamauchi, Atsushi

    2016-01-01

    A 71-year-old woman with polymyositis presenting with left thigh pain and an intermittent fever was admitted to Osaka Rosai Hospital. We initially diagnosed that her pain and fever were caused by a soft tissue infection because her polymyositis was controlled. She did not respond to various antibiotic therapies. Chest computed tomography demonstrated miliary tuberculosis (TB). Ziehl-Neelsen staining of liver biopsy specimens revealed epithelioid cell granuloma and acid-fast bacilli. Therefore, we finally diagnosed the lesion as TB fasciitis that improved with anti-TB drug therapy. The atypical presentation of TB fasciitis demonstrates the clinical importance of eliminating TB infections in immunocompromised hosts. PMID:27803421

  19. Massive progression of annuloaortic ectasia in a patient with Takayasu aortitis

    PubMed Central

    Inoue, Takehiro; Matsumoto, Teruhumi; Saga, Toshihiko

    2007-01-01

    A 52-year-old woman with Takayasu aortitis had undergone coronary artery bypass grafting and left subclavian artery reconstruction two years before admission to the Kinki University Medical Hospital (Osaka, Japan). On this admission, marked annuloaortic ectasia with severe aortic regurgitation was noted on echocardiography and aortography. Because of refractory heart failure, a modified Bentall operation was performed. Considering the serious cardiovascular complications of Takayasu aortitis, such as aneurysmal dilation of the aortic root, coronary artery ostial stenosis and, frequently, the need for surgical intervention, patients should be monitored closely. PMID:17932577

  20. EGDM foam shell status report (TAT 95-049)

    SciTech Connect

    Lambert, S.; Overturf, G.; Cook, B.; Schroen-Carey, D.

    1995-06-27

    We have completed an investigation of a low density foam made from ethylene glycol dimethacrylate (EGDM). We are confident that we have attained foam properties similar to those reported by Osaka, such as foam density ({approximately}60 mg/cc) and visibility of optical interference fringes. However, the material undergoes significant shrinkage during supercritical CO{sub 2} drying which hinders additional target fabrication steps. We also discuss issues related to preparing shells using a droplet generator and overcoating this material with hydroxyethyl cellulose.

  1. Synthesis and characterization of diallyl phthalate prepolymers

    SciTech Connect

    Baker, G.K.; Parker, B.G.

    1982-12-01

    Methods for the laboratory synthesis of diallyl phthalate prepolymers were evaluated. The chemical, physical, and molecular weight properties of several prepolymers synthesized were also evaluated and compared to those properties exhibited by Dapon 35 and Daiso 35, manufactured by FMC Corporation and Osaka-Soda, respectively. Glass-filled molding compounds from four of the prepolymers having molecular weight distributions ranging from 1.9 to 40.2 were prepared and tested at the Monsanto Research Corporation, Mound Facility. The processing characteristics and physical and electrical properties of two molding compounds were found to be comparable to similar compounds made from Dapon 35 and Daiso 35.

  2. Construction of In-house Databases in a Corporation

    NASA Astrophysics Data System (ADS)

    Fujii, Yohzo

    The author outlines the inhouse technical information system, OSTI of Osaka Research Institute, Sumitomo Chemical company as an example of inhouse database construction and use at a chemical industry. This system is to compile database for technical information generated inside the Laboratory and to provide online searching as well as title lists of the latest data output from it aiming at effective use of information among the departments, prevention from overlapped research thema, and support of research activities. The system outline, characteristics, materials to be covered, input items and search examples are described.

  3. Decay curve study in a standard electron capture decay

    SciTech Connect

    Nishimura, D.; Fukuda, M.; Kisamori, K.; Kuwada, Y.; Makisaka, K.; Matsumiya, R.; Matsuta, K.; Mihara, M.; Takagi, A.; Yokoyama, R.; Izumikawa, T.; Ohtsubo, T.; Suzuki, T.; Yamaguchi, T.

    2010-05-12

    We have searched for a time-modulated decay in a standard electron capture experiment for {sup 140}Pr, in order to confirm a report from GSI, where an oscillatory decay has been observed for hydrogen-like {sup 140}Pr and {sup 142}Pm ions in the cooler storage ring. {sup 140}Pr has been produced with the {sup 140}Ce(p, n) reaction by a pulsed proton beam accelerated from the Van de Graaff accelerator at Osaka University. Resultant time dependence of the K{sub a}lpha and K{sub b}eta X-ray intensities from the daughter shows no oscillatory behavior.

  4. Stabilization of Gyrotron Frequency by PID Feedback Control on the Acceleration Voltage

    NASA Astrophysics Data System (ADS)

    Khutoryan, E. M.; Idehara, T.; Kuleshov, A. N.; Tatematsu, Y.; Yamaguchi, Y.; Matsuki, Y.; Fujiwara, T.

    2015-12-01

    The results of frequency stabilization by proportional-integral-derivative (PID) feedback control of acceleration voltage in the 460-GHz Gyrotron FU CW GVI (the official name in Osaka University is Gyrotron FU CW GOI) are presented. The experiment was organized on the basis of the frequency modulation by modulation of acceleration voltage of beam electrons. The frequency stabilization during 10 h experiment was better than 10-6, which is compared with the results of the frequency deviation in free-running gyrotron operation.

  5. FBIS report. Science and technology: Japan, January 21, 1997

    SciTech Connect

    1997-01-21

    ;Selected titles include: Fine Ceramics Center Observes Formation Process for Carbon Nanotubes; Hitachi Ltd. Develops Atomic Manipulation Technology; Structural Thermal Model Tests on Exposed Facility of Japanese Experiment Module for International Space Station; Status of Japan`s Intelligent Transport System; Status of AIST Fuel Cell Projects; Kawasaki Heavy to Conduct Demonstration Test for Internal Circulating Fluidized Bed Refuse Incinerator; Osaka Gas Develops New Battery Electrode Material for Lithium-Ion Battery; Toshiba Corp. Develops World`s Smallest DRAM Memory Cell; Ten Card Companies To Work on Secure Electronic Commerce; and Japan: Column Views DA Internal Bureau Recasting.

  6. Genetic Testing for Huntington's Disease in Parkinsonism.

    PubMed

    Rahman, M S; Nagai, Y; Popiel, H A; Fujikake, N; Okamoto, Y; Ahmed, M U; Islam, M A; Islam, M T; Ahmed, S; Rahman, K M; Uddin, M J; Dey, S K; Ahmed, Q; Hossain, M A; Jahan, N; Toda, T

    2010-10-01

    The study was conducted to find out Huntington's disease (HD) by genetic analysis from those presenting with parkinsonism in the Neurology department of Mymensingh Medical College & Hospital. A sample of about 5ml blood was collected by veni puncture in EDTA tube with informed consent from 9 patients & 7 healthy individuals after approval of the institutional ethics committee for genetic study. The neurological disorder along with a complete history and physical findings were recorded in a prescribed questionnaire by the neurologists of Mymensingh Medical College & Hospital. Extraction of genomic DNA from the venous blood using FlexiGene DNA kit (Qiagen, Japan) was performed in Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh, Bangladesh. The extracted DNA was stored and accumulated and then these DNA were sent to Division of Clinical Genetics, Department of Medical Genetics, Osaka University Medical School, Suita, Osaka 565 0871, Japan for PCR and further analysis. PCR amplification of the CAG repeat in the 1T15 gene was performed with primers HD1 and HD3. HD PCR products revealed the DNA product of about 110bp (no. of CAG repeats=21) to 150bp (no. of CAG repeats=34) in both healthy individual and suspected PD patient DNA.

  7. Movement strategies during car transfers in individuals with tetraplegia: a preliminary study.

    PubMed

    Kataoka, M; Yasuda, T; Kataoka, T; Ueda, E; Yonetsu, R; Okuda, K

    2012-06-01

    Three-dimensional kinematic analysis of car transfer (CT) movement in four adult males with C6 tetraplegia. The aim of the present study was to assess the normal transfer technique movement from a wheelchair to a car (that is, CT) in subjects with tetraplegia. A better understanding of CT movement is invaluable knowledge for spinal cord injury rehabilitation. This type of knowledge will improve rehabilitation programs so that patients with tetraplegia will have greater societal participation. School of Comprehensive Rehabilitation, Osaka Prefecture University, Osaka, Japan. Four adult males with C6 tetraplegia, an impairment grade of A according to the American Spinal Injury Association guidelines, took part in the study. The subjects used their own wheelchair and car in our assessments of their CT movement technique. Movements were assessed using a three-dimensional video analysis system with six digital video cameras. CT data, which included lateral displacement of the head and buttocks, and angular displacement of neck flexion and trunk forward inclination, were collected and correlation coefficients were calculated. All four subjects demonstrated negative correlations in lateral displacements greater than 0.70. As for correlation coefficients of angular displacement, two subjects demonstrated negative correlations (r = -0.98 and r = -0.77) and one subject demonstrated a positive correlation (r = 0.75). The neck flexion and trunk forward inclination strategy was different among the four subjects. Each subject with C6 tetraplegia demonstrated different strategies during CT movement.

  8. Impaired delivery outcomes in pregnancies following myomectomy compared to myoma-complicated pregnancies.

    PubMed

    Kinugasa-Taniguchi, Yukiko; Ueda, Yutaka; Hara-Ohyagi, Chifumi; Enomoto, Takayuki; Kanagawa, Takeshi; Kimura, Tadashi

    2011-01-01

    To compare obstetric and delivery outcomes between myoma-complicated pregnancies and pregnancies that follow myomectomy. Among the 7,589 deliveries performed in the Department of Obstetrics and Gynecology of the Osaka University Hospital, Osaka, Japan, from 1994 to 2007, women with a past history of myomectomy and those with myoma during their pregnancy were enrolled in this study. Their clinical records were reviewed retrospectively. The frequency of myomas detected during pregnancy significantly increased by 1.8-fold during the first 7-year period as compared with the latter 7-year period of the study (p < 0.001). The obstetric and delivery outcomes, including the rate of cesarean section, the rate of preterm delivery and the amount of blood loss at delivery, were better in pregnancies complicated with current myoma than those in pregnancies which had undergone previous myomectomy (p < 0.001, p = 0.002 and p = 0.005, respectively), with the exception of an increased need for analgesic medication. Myomectomy of large asymptomatic myomas does not improve future obstetric and delivery outcomes, indicating that most asymptomatic myomas should be managed conservatively in women still considering childbearing.

  9. Using Vertical Panoramic Images to Record a Historic Cemetery

    NASA Astrophysics Data System (ADS)

    Tommaselli, A. M. G.; Polidori, L.; Hasegawa, J. K.; Camargo, P. O.; Hirao, H.; Moraes, M. V. A.; Rissate, E. A., Jr.; Henrique, G. R.; Abreu, P. A. G.; Berveglieri, A.; Marcato, J., Jr.

    2013-07-01

    In 1919, during colonization of the West Region of São Paulo State, Brazil, the Ogassawara family built a cemetery and a school with donations received from the newspaper Osaka Mainichi Shimbum, in Osaka, Japan. The cemetery was closed by President Getúlio Vargas in 1942, during the Second World War. The architecture of the Japanese cemetery is a unique feature in Latin America. Even considering its historical and cultural relevance, there is a lack of geometric documentation about the location and features of the tombs and other buildings within the cemetery. As an alternative to provide detailed and fast georeferenced information about the area, it is proposed to use near vertical panoramic images taken with a digital camera with fisheye lens as the primary data followed by bundle adjustment and photogrammetric restitution. The aim of this paper is to present a feasibility study on the proposed technique with the assessment of the results with a strip of five panoramic images, taken over some graves in the Japanese cemetery. The results showed that a plant in a scale of 1 : 200 can be produced with photogrammetric restitution at a very low cost, when compared to topographic surveying or laser scanning. The paper will address the main advantages of this technique as well as its drawbacks, with quantitative analysis of the results achieved in this experiment.

  10. Comparison of two confocal micro-XRF spectrometers with different design aspects

    PubMed Central

    Smolek, S; Nakazawa, T; Tabe, A; Nakano, K; Tsuji, K; Streli, C; Wobrauschek, P

    2014-01-01

    Two different confocal micro X-ray fluorescence spectrometers have been developed and installed at Osaka City University and the Vienna University of Technology Atominstitut. The Osaka City University system is a high resolution spectrometer operating in air. The Vienna University of Technology Atominstitut spectrometer has a lower spatial resolution but is optimized for light element detection and operates under vacuum condition. The performance of both spectrometers was compared. In order to characterize the spatial resolution, a set of nine specially prepared single element thin film reference samples (500 nm in thickness, Al, Ti, Cr, Fe Ni, Cu, Zr, Mo, and Au) was used. Lower limits of detection were determined using the National Institute of Standards and Technology standard reference material glass standard 1412. A paint layer sample (cultural heritage application) and paint on automotive steel samples were analyzed with both instruments. The depth profile information was acquired by scanning the sample perpendicular to the surface. © 2013 The Authors. X-Ray Spectrometry published by John Wiley & Sons, Ltd. PMID:26430286

  11. Investigation of the environmental change pattern of Japan

    NASA Technical Reports Server (NTRS)

    Maruyasu, T. (Principal Investigator)

    1973-01-01

    The author has identified the following significant results. ERTS-1 imagery clearly identifies the relationships between the status of erosion, effluent patterns affected by the coastal current, and the cultural construction activities. Simple photographic techniques can be used for detecting water mass distribution separately from cloud cover and also noise caused by reflected sunlight from wave surfaces. Polluted water does not diffuse continuously into the oceanic water, but forms masses in the water in the Kuroshio area. The polluted or turbid water in the area just north of the Tomogashima Channel, the south outlet of the Osaka Bay, shows that the northward tidal current runs in a clockwise eddy at the tidal period when the imagery was taken. Such an eddy-like pattern of tidal current had never been revealed by conventional oceanographic data. A front between an oceanic water mass and a polluted water mass runs in a NW-SE direction in the central part of the Osaka Bay. The patterns of turbid water discharged from the Kii River and Yoshino River show a northward tidal current in the North Kii Straits. The pattern of lighter turbid or polluted water located in the northwest region of the North Kii straits suggests the existence of a clockwise eddy in the straits.

  12. Uemachi flexure zone investigated by borehole database and numeical simulation

    NASA Astrophysics Data System (ADS)

    Inoue, N.; Kitada, N.; Takemura, K.

    2014-12-01

    The Uemachi fault zone extending north and south, locates in the center of the Osaka City, in Japan. The Uemachi fault is a blind reverse fault and forms the flexure zone. The effects of the Uemachi flexure zone are considered in constructing of lifelines and buildings. In this region, the geomorphological survey is difficult because of the regression of transgression. Many organizations have carried out investigations of fault structures. Various surveys have been conducted, such as seismic reflection survey in and around Osaka. Many borehole data for construction conformations have been collected and the geotechnical borehole database has been constructed. The investigation with several geological borehole data provides the subsurface geological information to the geotechnical borehole database. Various numerical simulations have been carried out to investigate the growth of a blind reverse fault in unconsolidated sediments. The displacement of the basement was given in two ways. One is based on the fault movement, such as dislocation model, the other is a movement of basement block of hanging wall. The Drucker-Prager and elastic model were used for the sediment and basement, respectively. The simulation with low and high angle fault movements, show the good agree with the actual distribution of the marine clay inferred from borehole data in the northern and southern Uemachi fault flexure zone, respectively. This research is partly funded by the Comprehensive Research on the Uemachi Fault Zone (from FY2010 to FY2012) by The Ministry of Education, Culture, Sports, Science and Technology (MEXT).

  13. [Facts visualized through job support activities for mentally disordered persons--what is the objective of medical treatment for mental disorder?].

    PubMed

    Tagawa, Seiji

    2014-01-01

    According to a recent investigation by the Public Employment Security Office, the rate of employing mentally disordered persons is increasing. In the report, it was predicted that the number of employed mentally disordered persons will exceed the number of physically disordered persons within a few years, and will become the highest of the main three disabled types. Despite the strong desire of mentally disordered persons to work, supporting systems have been inadequate. In 2007, mental clinic doctors in Osaka took the lead and established the NPO Osaka Job Support Network for Mentally Disordered Persons (JSN) to support their employment persons. We aimed to establish a support system for mentally disordered persons who have a strong will to work, stating "I would like to work" to their family doctors, who introduce JSN to the patients, and then the family doctors and JSN cooperate to support the patients to realize the desire to "work". Since April 2013, 49 persons have found a job and "graduated" from JSN. Over 6 years until the end of March, 2013, a total of 154 persons found jobs and "graduated" from JSN. From now on, it is expected that around 50 persons will find jobs and "graduate" from JSN every year. It is definitely insufficient just to repeat "temporary" medical treatment for mental disorders with a long course like schizophrenia. A care management view that values the hopes and dreams of patients is required in psychiatric treatment.

  14. Comparison of two confocal micro-XRF spectrometers with different design aspects.

    PubMed

    Smolek, S; Nakazawa, T; Tabe, A; Nakano, K; Tsuji, K; Streli, C; Wobrauschek, P

    2014-03-01

    Two different confocal micro X-ray fluorescence spectrometers have been developed and installed at Osaka City University and the Vienna University of Technology Atominstitut. The Osaka City University system is a high resolution spectrometer operating in air. The Vienna University of Technology Atominstitut spectrometer has a lower spatial resolution but is optimized for light element detection and operates under vacuum condition. The performance of both spectrometers was compared. In order to characterize the spatial resolution, a set of nine specially prepared single element thin film reference samples (500 nm in thickness, Al, Ti, Cr, Fe Ni, Cu, Zr, Mo, and Au) was used. Lower limits of detection were determined using the National Institute of Standards and Technology standard reference material glass standard 1412. A paint layer sample (cultural heritage application) and paint on automotive steel samples were analyzed with both instruments. The depth profile information was acquired by scanning the sample perpendicular to the surface. © 2013 The Authors. X-Ray Spectrometry published by John Wiley & Sons, Ltd.

  15. Osteosarcoma arising from the parapharyngeal space: A case report

    PubMed Central

    HOSHI, MANABU; TAKADA, JUN; OEBISU, NAOTO; NAKAMURA, HIROAKI

    2014-01-01

    The current study presents a rare case of osteoblastic osteosarcoma arising from an extremely rare site, namely, the parapharyngeal space. To the best of our knowledge, this is the first study of computed tomography (CT) and magnetic resonance imaging (MRI) of an osteosarcoma in the parapharyngeal space with pathological correlation. A 56-year-old male presented with a mass of the right facial region. CT and MRI showed a heterogeneous mass, with ossification or calcification, occupying the parapharyngeal space. Open biopsy revealed an osteoblastic osteosarcoma containing calcified malignant osteoid. Lung CT also showed multiple lung metastases at the time of the first visit to the Department of Orthopedic Surgery, Osaka City University Graduate School of Medicine (Osaka, Japan). Systemic chemotherapy and radiotherapy were administered to the patient for palliation. The patient was alive at the 24-month follow-up subsequent to this treatment. Although a definitive diagnosis requires the use of a biopsy, the CT and MRI findings described in the present study suggest inclusion of this rare tumor in the differential diagnosis that is formed when such findings occur in the parapharyngeal space. The present study also briefly discusses osteosarcoma of the parapharyngeal space. PMID:25120697

  16. The Development of 460 GHz gyrotrons for 700 MHz DNP-NMR spectroscopy

    NASA Astrophysics Data System (ADS)

    Idehara, T.; Tatematsu, Y.; Yamaguchi, Y.; Khutoryan, E. M.; Kuleshov, A. N.; Ueda, K.; Matsuki, Y.; Fujiwara, T.

    2015-07-01

    Two demountable gyrotrons with internal mode converters were developded as sub-THz radiation sources for 700 MHz DNP (Dynamic Nuclear Polarization) enhanced NMR spectroscopy. Experimental study on the DNP-NMR spectroscopy will be carried out in Osaka University, Institute for Protein Research, as a collaboration with FIR UF. Both gyrotrons operate near 460 GHz and the output CW power measured at the end of transmission system made by circular waveguides is typically 20 to 30 watts. One of them named Gyrotron FU CW GVI (we are using "Gyrotron FU CW GO-1" as an official name in Osaka University) is designed to have a special function of high speed frequency modulation δ f within 100 MHz band. This will expand excitable band width of ESR and increase the number of electron spins contributing to DNP. The other gyrotron, Gyrotron FU CW GVIA ("Gyrotron FU CW GO-II") has a function of frequency tunability Δ f in the range of wider than 1.5 GHz, which is achieved in steady state by changing magnetic field intensity. This function should be used for adjusting the output frequency at the optimal value to achieve the highest enhancement factor of DNP.

  17. A Study on Site Diversity Techniques Related to Rain Area Motion Using Ku-Band Satellite Signals

    NASA Astrophysics Data System (ADS)

    Maekawa, Yasuyuki; Nakatani, Takayuki; Shibagaki, Yoshiaki; Hatsuda, Takeshi

    Directions and speeds of the motion of rain areas are estimated for each type of rain fronts, using time differences detected in the rain attenuation of the Ku-band satellite radio wave signals that have been measured at Osaka Electro-Communication University (OECU) in Neyagawa, Osaka, Research Institute of Sustainable Humanosphere (RISH) in Uji, Kyoto, and MU Observatory (MU) of Kyoto University in Shigaraki, Shiga, for the past five years since September 2002. These directions and speeds are shown to agree well with those directly obtained from the motion of rain fronts in the weather charts published by Japan Meteorological Agency. The rain area motion is found to have characteristic directions according to each rain type, such as cold and warm fronts or typhoon. A numerical estimate of the effects of site diversity techniques indicates that between two sites among the three locations (OECU, RISH, MU) separated by 20-50km, the joint cumulative time percentages of rain attenuation become lower as the two sites are aligned along the directions of rain area motion. In such a case, compared with the ITU-R recommendations, the distance required between the two sites may be, on an average, reduced down to about 60-70% of the conventional predictions.

  18. myPresto/omegagene: a GPU-accelerated molecular dynamics simulator tailored for enhanced conformational sampling methods with a non-Ewald electrostatic scheme

    PubMed Central

    Kasahara, Kota; Ma, Benson; Goto, Kota; Dasgupta, Bhaskar; Higo, Junichi; Fukuda, Ikuo; Mashimo, Tadaaki; Akiyama, Yutaka; Nakamura, Haruki

    2016-01-01

    Molecular dynamics (MD) is a promising computational approach to investigate dynamical behavior of molecular systems at the atomic level. Here, we present a new MD simulation engine named “myPresto/omegagene” that is tailored for enhanced conformational sampling methods with a non-Ewald electrostatic potential scheme. Our enhanced conformational sampling methods, e.g., the virtual-system-coupled multi-canonical MD (V-McMD) method, replace a multi-process parallelized run with multiple independent runs to avoid inter-node communication overhead. In addition, adopting the non-Ewald-based zero-multipole summation method (ZMM) makes it possible to eliminate the Fourier space calculations altogether. The combination of these state-of-the-art techniques realizes efficient and accurate calculations of the conformational ensemble at an equilibrium state. By taking these advantages, myPresto/omegagene is specialized for the single process execution with Graphics Processing Unit (GPU). We performed benchmark simulations for the 20-mer peptide, Trp-cage, with explicit solvent. One of the most thermodynamically stable conformations generated by the V-McMD simulation is very similar to an experimentally solved native conformation. Furthermore, the computation speed is four-times faster than that of our previous simulation engine, myPresto/psygene-G. The new simulator, myPresto/omegagene, is freely available at the following URLs: http://www.protein.osaka-u.ac.jp/rcsfp/pi/omegagene/ and http://presto.protein.osaka-u.ac.jp/myPresto4/. PMID:27924276

  19. Laser processing centers and their research projects in Japan

    SciTech Connect

    Matsunawa, Akira

    1995-06-01

    In Japan, R and D activities on laser materials processing are mainly conducted in universities, public research institutions, and technical centers in private enterprise. Among them the Welding Research institute and the Department of Welding and Production Engineering, both at Osaka University, have taken the initiative in conducting fundamental studies on laser materials processing as well as training experts and engineers in laser technology since the mid 1960s. In 1990, a new laser center called the Applied Laser Engineering Center (ALEC) was established in Nagaoka City in Niigata Prefecture by the investments of New Energy and Industrial Technology Development Organization (NEDO), Niigata Prefecture, City of Nagaoka, and many private companies in order to develop industrial applications of laser technologies. The Center has a wide variety of lasers covering wavelengths from infrared to ultraviolet, and many research projects are carried out under the sponsorship of the government, self-governing bodies, and private companies. Another new laser center, the Advanced Materials Processing Institute (AMPI), was recently established in Amagasaki City, a neighboring city to Osaka, under the sponsorship of the City of Amagasaki and many private enterprises, where a 50 kW CO{sub 2} laser and a 5 kW YAG laser (fiber combining two 2 kW CW lasers and a 1 kW pulsed laser) were installed in November 1994. Major targets of the R and D are the development of laser welding and cutting of thicker materials, laser surface modification, and hybrid plasma-laser thermal spraying.

  20. Oxidation efficiencies of nitrite to nitrate by freezing of field rain samples

    SciTech Connect

    Takenaka, Norimichi; Daimon, Tohru; Sato, Keiichi

    1996-12-31

    Nitrite is known to be oxidized to nitrate by freezing much more rapidly than in solution. Furthermore, the oxidation efficiency of nitrite to nitrate by freezing is varied by pH or kinds and concentration of coexistences. We report here the oxidation efficiencies of nitrite to nitrate by freezing of field rain samples. The field rain samples were collected at Mt. Ikoma, which is located at about 20 km east of Osaka city, and Osaka Prefecture University. Concentration of nitrite was usually sub to a few {mu}mol/L order in rain and {mu}mol/L order in fog and less than 1 {mu}mol/L in snow. The highest value of nitrite concentration was 43 {mu}mol/L in rain and 620 {mu}mol/L in fog. Nitrite was oxidized immediately to nitrate by freezing at pH lower than 5.2, even when the sample droplet (about 1 mm diameter) was frozen very quickly in liquid nitrogen (77K). The oxidation efficiency was higher at lower pH. However, the efficiency varied from sample to sample. This is probably due to that kinds and concentration of coexistences were difference between samples. The effect of solutes will be also reported. Freezing of rain droplets are observed in freezing of super cooled droplets, growing of graupel and hail, growing of cumulonimbus, and so on. Ratio of nitrate to nitrite was higher in snow than that in rain or fog.

  1. Optimization of bow shape for a non ballast water ship

    NASA Astrophysics Data System (ADS)

    Van He, Ngo; Ikeda, Yoshiho

    2013-09-01

    In this research, a commercial CFD code "Fluent" was applied to optimization of bulbous bow shape for a non ballast water ships (NBS). The ship was developed at the Laboratory of the authors in Osaka Prefecture University, Japan. At first, accuracy of the CFD code was validated by comparing the CFD results with experimental results at towing tank of Osaka Prefecture University. In the optimizing process, the resistances acting on ships in calm water and in regular head waves were defined as the object function. Following features of bulbous bow shapes were considered as design parameters: volume of bulbous bow, height of its volume center, angle of bow bottom, and length of bulbous bow. When referring to the computed results given by the CFD like resistance, pressure and wave pattern made by ships in calm water and in waves, an optimal bow shape for ships was discovered by comparing the results in the series of bow shapes. In the computation on waves, the ship is in fully captured condition because shorter waves, λ/ L pp <0.6, are assumed.

  2. Distribution and pollutant load of hexabromocyclododecane (HBCD) in sewage treatment plants and water from Japanese Rivers.

    PubMed

    Ichihara, Makiko; Yamamoto, Atsushi; Takakura, Koh-ichi; Kakutani, Naoya; Sudo, Miki

    2014-09-01

    Hexabromocyclododecane diastereoisomers (α-, β-, γ-, δ-, and ε-HBCD) were investigated in river water, sewage influent, and sewage effluent from the Yodo River basin, Japan. The mean annual values of HBCDs ranged from 0.19 to 14ngL(-1) in river water. We observed that the concentrations of HBCDs in the brackish water area were low compared with that in the fresh water area. It was implied that, when the flow of the river stagnated in the estuarine area, HBCDs settled with suspended matter because of their hydrophobic character. In the sewage treatment plants, HBCDs ranged from 16 to 400ngL(-1) in sewage influent, whereas they ranged from 0.39 to 12ngL(-1) in sewage effluent. Over 90% of HBCDs were removed from the wastewater in the sewage treatment plants. By using these results, we estimated the pollutant load of HBCDs that flows into Osaka Bay from the study area. It was estimated that approximately 15kg of HBCDs flow into Osaka Bay from the study area in a year. This value is five orders of magnitude lower than the 2010 market demand for HBCDs (3019 metrictons) in Japan.

  3. Comparison of waste prevention behaviors among three Japanese megacity regions in the context of local measures and socio-demographics.

    PubMed

    Kurisu, Kiyo H; Bortoleto, Ana Paula

    2011-07-01

    Waste prevention behaviors (WPBs) should be investigated separately from recycling behaviors and analyzed in the context of local policies and measures. Previous studies on WPBs have been mainly conducted in the USA and Europe (mainly in the UK), and studies in Japan have remained very limited to date. Moreover, the effects of socio-demographic factors have been rarely described correctly based on appropriate large sampling. In this study, we conducted an on-line questionnaire survey and obtained 8000 respondents in three megacity regions (Tokyo, Osaka, and Aichi) in Japan. Among these three regions, Osaka respondents showed significantly lower practice rates in nine of 18 WPBs. Particularly in My-bag behavior, the charging of plastic shopping bags strongly affects the practice rate. As shown in the results, local policies and measures affect WPBs. Based on the practice rates, latent four factors were extracted by factor analysis. Multiple regression analysis revealed that gender and age significantly affect WPB factors before local policy effects. Copyright © 2011 Elsevier Ltd. All rights reserved.

  4. myPresto/omegagene: a GPU-accelerated molecular dynamics simulator tailored for enhanced conformational sampling methods with a non-Ewald electrostatic scheme.

    PubMed

    Kasahara, Kota; Ma, Benson; Goto, Kota; Dasgupta, Bhaskar; Higo, Junichi; Fukuda, Ikuo; Mashimo, Tadaaki; Akiyama, Yutaka; Nakamura, Haruki

    2016-01-01

    Molecular dynamics (MD) is a promising computational approach to investigate dynamical behavior of molecular systems at the atomic level. Here, we present a new MD simulation engine named "myPresto/omegagene" that is tailored for enhanced conformational sampling methods with a non-Ewald electrostatic potential scheme. Our enhanced conformational sampling methods, e.g., the virtual-system-coupled multi-canonical MD (V-McMD) method, replace a multi-process parallelized run with multiple independent runs to avoid inter-node communication overhead. In addition, adopting the non-Ewald-based zero-multipole summation method (ZMM) makes it possible to eliminate the Fourier space calculations altogether. The combination of these state-of-the-art techniques realizes efficient and accurate calculations of the conformational ensemble at an equilibrium state. By taking these advantages, myPresto/omegagene is specialized for the single process execution with Graphics Processing Unit (GPU). We performed benchmark simulations for the 20-mer peptide, Trp-cage, with explicit solvent. One of the most thermodynamically stable conformations generated by the V-McMD simulation is very similar to an experimentally solved native conformation. Furthermore, the computation speed is four-times faster than that of our previous simulation engine, myPresto/psygene-G. The new simulator, myPresto/omegagene, is freely available at the following URLs: http://www.protein.osaka-u.ac.jp/rcsfp/pi/omegagene/ and http://presto.protein.osaka-u.ac.jp/myPresto4/.

  5. Agglutination of human O erythrocytes by influenza A(H1N1) viruses freshly isolated from patients.

    PubMed

    Murakami, T; Haruki, K; Seto, Y; Kimura, T; Minoshiro, S; Shibe, K

    1991-04-01

    The hemagglutinin titers of 10 influenza A (H1N1) viruses were examined using the erythrocytes of several species. Human O erythrocytes showed the highest agglutination titer to the viruses, whereas chicken erythrocytes showed a low titer. These findings were noted for at least 10 passages by serial dilutions of the viruses in Madin-Darby canine kidney (MDCK) cells. All influenza A(H1N1) viruses, plaque-cloned directly from throat-washing specimens of patients, also agglutinated human O but not chicken erythrocytes. The results of a hemadsorption test indicated that chicken erythrocytes possess less affinity to MDCK cells infected with the A/Osaka City/2/88(H1N1) stain than to those infected with the A/Yamagata/120/86(H1N1) strain which is used as an inactivated influenza vaccine in Japan. However, there were no significant differences between the A/Osaka City/2/88 and the A/Yamagata/120/86 strains in the hemagglutination inhibition test. Since human O erythrocytes have high agglutination activity to influenza A(H1N1) and also to A(H3N2) and B viruses in MDCK cells, these erythrocytes may be useful for the serological diagnosis of influenza.

  6. Depolarization ratios retrieved by AERONET sun-sky radiometer data and comparison to depolarization ratios measured with lidar

    NASA Astrophysics Data System (ADS)

    Noh, Youngmin; Müller, Detlef; Lee, Kyunghwa; Kim, Kwanchul; Lee, Kwonho; Shimizu, Atsushi; Kim, Sang-Woo; Sano, Itaru; Park, Chan Bong

    2017-05-01

    The linear particle depolarization ratios at 440, 675, 870, and 1020 nm were derived using data taken with the AERONET sun-sky radiometer at Seoul (37.45° N, 126.95° E), Kongju (36.47° N, 127.14° E), Gosan (33.29° N, 126.16° E), and Osaka (34.65° N, 135.59° E). The results are compared to the linear particle depolarization ratio measured by lidar at 532 nm. The correlation coefficient R2 between the linear particle depolarization ratio derived by AERONET data at 1020 nm and the linear particle depolarization ratio measured with lidar at 532 nm is 0.90, 0.92, 0.79, and 0.89 at Seoul, Kongju, Gosan, and Osaka, respectively. The correlation coefficients between the lidar-measured depolarization ratio at 532 nm and that retrieved by AERONET at 870 nm are 0.89, 0.92, 0.76, and 0.88 at Seoul, Kongju, Gosan, and Osaka, respectively. The correlation coefficients for the data taken at 675 nm are lower than the correlation coefficients at 870 and 1020 nm, respectively. Values are 0.81, 0.90, 0.64, and 0.81 at Seoul, Kongju, Gosan, and Osaka, respectively. The lowest correlation values are found for the AERONET-derived linear particle depolarization ratio at 440 nm, i.e., 0.38, 0.62, 0.26, and 0.28 at Seoul, Kongju, Gosan, and Osaka, respectively. We should expect a higher correlation between lidar-measured linear particle depolarization ratios at 532 nm and the ones derived from AERONET at 675 and 440 nm as the lidar wavelength is between the two AERONET wavelengths. We cannot currently explain why we find better correlation between lidar and AERONET linear particle depolarization ratios for the case that the AERONET wavelengths (675, 870, and 1020 nm) are significantly larger than the lidar measurement wavelength (532 nm). The linear particle depolarization ratio can be used as a parameter to obtain insight into the variation of optical and microphysical properties of dust when it is mixed with anthropogenic pollution particles. The single-scattering albedo

  7. Tracing Anthropogenic Osmium around Japan using the Osmium Isotopic Composition of Macroalgae

    NASA Astrophysics Data System (ADS)

    Sproson, A. D.; Selby, D. S.; Suzuki, K.

    2016-12-01

    The present-day open ocean seawater 187Os/188Os value of 1.06 is seen to reflect the balance between unradiogenic mantle derived osmium (Os) and radiogenic continental Os. However, Os released by anthropogenic activities has been detected in coastal sediments, lakes, estuaries, rain and snow from sources such as sewage sludge, catalytic convertors, smelting, fossil fuel burning and use as a staining reagent, thereby impacting the global Os budget. Despite over two decades of research, contemporary Os inputs into the ocean are believed to be underestimated by a factor of 3, leading to discrepancies in oceanic Os residence times estimated from mass balance calculations. This, in part, is due to the problems associated with directly measuring ultra-low concentrations of Os in seawater. Recently, it has been proposed that the 187Os/188Os of macroalgae (seaweed) reflects that of the seawater in which it lives. This suggests macroalgae can act as a proxy for the Os isotopic composition of seawater. We present Os isotope data for macroalgae collected from Tokyo Bay, Osaka Bay, the Noto Peninsula, Izu Peninsula and Hokkaido. Macroalgae close to the major cities of Tokyo and Osaka exhibit unradiogenic 187Os/188Os values as low as 0.45, in agreement with published sediment data. As you move away from central Tokyo and Osaka, 187Os/188Os values become more radiogenic, reaching values as high as 0.95 due to the entrainment of more radiogenic seawater. Macroalgae from the less urbanised Noto and Izu Peninsulas show a radiogenic 187Os/188Os range of 0.70-0.91, close to global river estimates suggesting little contamination from anthropogenic processes. Deep-water species off the coast of Hokkaido exhibit 187Os/188Os values in agreement with published Pacific Ocean seawater data. We propose macroalgae is recording the influence of anthropogenic processes - in particular sewage sludge production and catalytic convertor exhaust - on the Os budget of Japanese waters. Therefore

  8. PREFACE: International Symposium on Materials Science and Innovation for Sustainable Society - Eco-Materials and Eco-Innovation for Global Sustainability - The 21st Iketani Conference 2011

    NASA Astrophysics Data System (ADS)

    Takahashi, Yasuo

    2012-08-01

    Conference logo The 21st century has been called the century of environmental revolution. Green innovations and environmentally friendly production systems based on physics, chemistry, materials science, and electronic engineering will be indispensable for ensuring renewable energy and establishing a sustainable society. In particular, production design, materials processing, and fabrication technologies such as welding and joining will be very important components of such green innovations. For these reasons, the International Symposium on Materials Science and Innovation for Sustainable Society - eco-materials and eco-innovation for global sustainability - (ECO-MATES 2011) was organized by the Joining and Welding Research Institute (JWRI) and the Center of Environmental Innovation Design for Sustainability (CEIDS), Osaka University. ECO-MATES 2011 was held at Hotel Hankyu Expo Park, Osaka, Japan from 28-30 November 2011. 435 participants from 20 countries around the world attended the symposium. 149 oral presentations including 60 invited talks and 160 posters were presented at the symposium to discuss the latest research and developments in green innovations in relation to environmental issues. The topics of the symposium covered all environmentally related fields including renewable energy, energy-materials, environment and resources, waste and biomass, power electronics, semiconductor, rare-earth metals, functional materials, organic electronics materials, electronics packaging, smart processing, joining and welding, eco-efficient processes, and green applied physics and chemistry. Therefore, 55 full papers concerning green innovations and environmentally benign production were selected and approved by the editorial board and the program committee of ECO-MATES 2011. All papers were accepted through peer review processes. I believe that all the papers have many informative contents. On behalf of the steering committee of the symposium, I would like to express

  9. Variation of aerosol characteristics in the detail scale of time and space

    NASA Astrophysics Data System (ADS)

    Mukai, S.; Nakata, M.; Sano, I.

    2012-04-01

    In this work, we intend to demonstrate the spatial and temporal variation of atmospheric aerosols around AERONET/Osaka site. Osaka is the second big city in Japan and a typical Asian urban area. It is well known that the aerosol distribution in Asia is complicated due to the increasing emissions of anthropogenic aerosols in association with economic growth and in addition behavior of natural dusts significantly varies with the seasons. Therefore local spatially and temporally resolved measurements of atmospheric particles in Asian urban city are meaningful. We equip various ground measurement devices of atmosphere in the campus of Kinki University (KU). The data supplied by the Cimel instrument are analyzed with a standard AERONET (Aerosol Robotics Network) processing system. It provides us with Aerosol optical thickness (AOT), the Ångström exponent and so on. We set up a PM sampler and a standard instrument of NIES/LIDAR network attached to our AERONET site. The PM sampler provides particle information about the concentrations of PM2.5, PM10 and OBC separately. In addition to the simultaneous measurements, we make observation of the air quality at several locations in the neighbour-hood using portable sun-photometers (Solar-Light Company Microtops-2). The simultaneous measurements of aerosols and numerical model simulations indicate that the spatial and temporal factors influence the characterization of atmospheric particles especially in dust event. Then we observe the air quality at such several locations within a few 10 km area from KU, as Izumi and Nara, in ordinal days and dust days. Izumi site locates near industrial area and Nara is in the east of KU beyond the mountain-Ikoma. It is found from the simultaneous measurements at these three sites that AOT at Izumi in ordinal days is the highest and Nara's lowest. It indicates that the Ikoma-mountains block off the polluted air from the west. However in dust days, AOT at Nara is as large as that at Higashi-Osaka

  10. High temperature tubular solid oxide fuel cell development

    NASA Astrophysics Data System (ADS)

    Ray, E. R.

    Important to the development commercialization of any new technology is a field test program. This is a mutually beneficial program for both the developer and the prospective user. The developer is able to acquire valuable field operating experience that is not available in a laboratory while the user has the opportunity to become familiar with the new technology and gains a working knowledge of it through hands-on experience. Westinghouse, recognizing these benefits, initiated a program in 1986 by supplying a 400 W SOFC generator to Tennessee Valley Authority. This generator operated for approximately 1,760 hours and was constructed of twenty-four 30 cm thick-wall PST cells. In 1987, three, 3 kW SOFC generators were installed and operated at the facilities of the Tokyo Gas Company and the Osaka Gas Company. At Osaka Gas, two generators were used. First a training generator, operated for 2900 hours before it was replaced on a preplanned schedule with the second generator. The second generator operated for 3,600 hours. Tokyo Gas generator was operated for 4,900 hours. These generators had a 98 percent availability and measured NO(x) levels of less than 1.3 ppm. The 3 kW SOFC generators were constructed of 144 36 cm thick-wall PST cells. The 3 kW generators, as was the TVA generator, were fueled with hydrogen and carbon monoxide. The next major milestone in the field unit program was reached in early 1992 with the delivery to the UTILITIES, a consortium of the Kansai Electric Power company, the Tokyo Gas Company, and the Osaka Gas Company, of a natural gas fueled all electric SOFC system. This system is rated at a nominal 25 kW dc with a peak capacity of 40 kW dc. The NO(x) was measured at less than 0.3 ppM (corrected to 15 percent oxygen). The system consists of 1152 cells (thin-wall PST) of 50 cm active length, manufactured at the PPMF. Cells are contained in two independently controlled and operated generators.

  11. Level Structure Above the T1/2 = 2 . 0 ×105 yr Isomer in 186Re

    NASA Astrophysics Data System (ADS)

    Matters, D. A.; McClory, J. W.; Kondev, F. G.; Carpenter, M. P.; Carroll, J. J.; Chiara, C. J.; Lane, G. J.; Kibédi, T.; Ideguchi, E.; Fang, Y.; Watanabe, H.; E435 Cagra Collaboration

    2016-03-01

    The level structure above the Kπ = (8+) , 149-keV isomer in 186Re is largely undeveloped. The isomer could play a role in the s-process nucleosynthesis of 187Os and 187Re and affect the accuracy of the Re-Os cosmochronometer. An experiment was conducted at the Research Center for Nuclear Physics (RCNP) at Osaka University, Japan, using the Clover Array Gamma-ray spectrometer at RCNP/RIBF for Advanced research (CAGRA) to measure γ-ray coincidences from (d , 2 n) reactions on an enriched 186W target. The γ - γ coincidence data obtained from the CAGRA array were analyzed along with data from a similar experiment performed in 2006 at the Australian National University. A preliminary analysis of the data reveals several new levels and transitions feeding the 186mRe isomer.

  12. Integrated simulations for ion beam assisted fast ignition

    NASA Astrophysics Data System (ADS)

    Sakagami, H.; Johzaki, T.; Sunahara, A.; Nagatomo, H.

    2016-03-01

    Although the energy conversion efficiency from the heating laser to fast electrons is high, the coupling efficiency from fast electrons to the core is estimated to be very low due to large divergence angle of fast electrons in fast ignition experiments at ILE, Osaka University. To mitigate this problem, a plastic thin film or low-density foam, which can generate not only proton (H+) but also carbon (C6+) beams, is combined with currently used cone-guided targets and additional core heating by ions is expected. According to integrated simulations, it is found that these ion beams can enhance the core heating by 20∼60% and it shows a possibility of ion beam assisted fast ignition.

  13. An observational study of insomnia and nightmare treated with trazodone in patients with advanced cancer.

    PubMed

    Tanimukai, Hitoshi; Murai, Tasuku; Okazaki, Namiko; Matsuda, Yoichi; Okamoto, Yoshiaki; Kabeshita, Yasunobu; Ohno, Yumiko; Tsuneto, Satoru

    2013-06-01

    Patients with cancer often experience insomnia. Nightmares are also a strong factor that interferes with the maintenance of comfortable and satisfying sleep. However, the prevalence and standard treatment of nightmares in patients with cancer have not been established yet. We aimed to treat insomnia and nightmares with trazodone. From 2008 to 2011, trazodone was prescribed to 30 patients with cancer who reported experiencing insomnia with or without nightmares to the palliative care team in Osaka University Hospital. Effective treatment was seen in 15 patients (50%). Four patients with cancer reported having severe nightmares and 2 patients had beneficial effects, with frightening dreams transformed into acceptable ones. Trazodone may be an effective drug for the treatment of insomnia and nightmares in patients with advanced cancer.

  14. The Mucool/mice LH2 Absorber Program

    NASA Astrophysics Data System (ADS)

    Cummings, M. A. C.

    The continuing LH2 R & D by the MuCool group, conducted by Illinois Consortium for Accelerator Research (ICAR) institutions (NIU, IIT and UIUC), the University of Mississippi, Oxford University and Fermilab, are summarized here, including results for the first hydrogen tests of an absorber prototype from Osaka University and KEK cooled by internal convection at the newly constructed FNAL MuCool Test Area (MTA). The program includes designs for the high-powered test of an absorber prototype (external heat exchange) at the MTA which are nearing completion to be installed by fall 2005, an alternative absorber design (internal heat exchange) being finalized for the approved cooling experiment (MICE) at Rutherford-Appleton Laboratory, and a novel idea for gaseous hydrogen absorbers being developed at Fermilab for a high powered test at the MTA in 2006.

  15. Accessibility condition of wave propagation and multicharged ion production in electron cyclotron resonance ion source plasma.

    PubMed

    Kato, Yushi; Yano, Keisuke; Nishiokada, Takuya; Nagaya, Tomoki; Kimura, Daiju; Kumakura, Sho; Imai, Youta; Hagino, Shogo; Otsuka, Takuro; Sato, Fuminobu

    2016-02-01

    A new tandem type source of electron cyclotron resonance (ECR) plasmas has been constructing for producing synthesized ion beams in Osaka University. Magnetic mirror field configuration with octupole magnets can be controlled to various shape of ECR zones, namely, in the 2nd stage plasma to be available by a pair mirror and a supplemental coil. Noteworthy correlations between these magnetic configurations and production of multicharged ions are investigated in detail, as well as their optimum conditions. We have been considering accessibility condition of electromagnetic and electrostatic waves propagating in ECR ion source plasma, and then investigated their correspondence relationships with production of multicharged ions. It has been clarified that there exits efficient configuration of ECR zones for producing multicharged ion beams experimentally, and then has been suggested from detail accessibility conditions on the ECR plasma that new resonance, i.e., upper hybrid resonance, must have occurred.

  16. Clinico-pathological aspects of a residual natal tooth: a case report.

    PubMed

    Tsubone, Hanako; Onishi, Tomoyuki; Hayashibara, Tetsuyuki; Sobue, Shizuo; Ooshima, Takashi

    2002-04-01

    A Japanese girl was referred to Osaka University Dental Hospital for examination of a tooth-like structure that had erupted following spontaneous exfoliation of a natal tooth in the lower left primary central incisor region. The structure had erupted at 6 months of age, and radiographic and clinical examination showed composition of pulp and dentin, but no enamel. On histological examination, the majority of the dentin area had a tubular dentin-like appearance, while the outer area of the root appeared to be composed of an osteodentin-like substance. Most of the dentin was covered by cementum. These findings suggest that the structure had originated from a developing remnant of the extracted natal tooth, which must have remained in the gingival tissues. We termed this calcified structure a residual natal tooth.

  17. Characterization of the PTW 34031 ionization chamber (PMI) at RCNP with high energy neutrons ranging from 100 - 392 MeV

    NASA Astrophysics Data System (ADS)

    Theis, C.; Carbonez, P.; Feldbaumer, E.; Forkel-Wirth, D.; Jaegerhofer, L.; Pangallo, M.; Perrin, D.; Urscheler, C.; Roesler, S.; Vincke, H.; Widorski, M.; Iwamoto, Y.; Hagiwara, M.; Satoh, D.; Iwase, H.; Yashima, H.; Matsumoto, T.; Masuda, A.; Nishiyama, J.; Harano, H.; Itoga, T.; Nakamura, T.; Sato, T.; Nakane, Y.; Nakashima, H.; Sakamoto, Y.; Taniguchi, S.; Nakao, N.; Tamii, A.; Shima, T.; Hatanaka, K.

    2017-09-01

    Radiation monitoring at high energy proton accelerators poses a considerable challenge due to the complexity of the encountered stray radiation fields. These environments comprise a wide variety of different particle types and span from fractions of electron-volts up to several terra electron-volts. As a consequence the use of Monte Carlo simulation programs like FLUKA is indispensable to obtain appropriate field-specific calibration factors. At many locations of the LHC a large contribution to the particle fluence is expected to originate from high-energy neutrons and thus, benchmark experiments with mono-energetic neutron beams are of high importance to verify the aforementioned detector response calculations. This paper summarizes the results of a series of benchmark experiments with quasi mono-energetic neutrons of 100, 140, 200, 250 and 392 MeV that have been carried out at RCNP - Osaka University, during several campaigns between 2006 and 2014.

  18. Impact of genotype-specific herd immunity on the circulatory dynamism of norovirus: a 10-year longitudinal study of viral acute gastroenteritis.

    PubMed

    Sakon, Naomi; Yamazaki, Kenji; Nakata, Keiko; Kanbayashi, Daiki; Yoda, Tomoko; Mantani, Masanobu; Kase, Tetsuo; Takahashi, Kazuo; Komano, Jun

    2015-03-15

    Human norovirus is a major cause of viral acute gastroenteritis worldwide. However, the transition of endemic norovirus genotypes remains poorly understood. The characteristics of natural immunity against norovirus are unclear because few studies have been performed in the natural infection setting. This prospective 10-year surveillance study of acute gastroenteritis in the province of Osaka, Japan, revealed that norovirus spread shows temporal, geographic, and age group-specific features in the humans. Genogroup II genotype 4 (GII.4) was detected in most sporadic pediatric cases, as well as in foodborne and nursing home outbreaks, respectively. The dominant genotypes in outbreaks at childcare facilities and schools shifted every season and involved GI, GII.2, GII.3, GII.4, and GII.6. Evidence at both the facility and individual levels indicated that genotype-specific herd immunity lasted long enough to influence the endemic norovirus genotype in the next season. Thus, norovirus circulates through human populations in a uniquely dynamic fashion.

  19. Effect of road transportation on the serum biochemical parameters of cynomolgus monkeys and beagle dogs.

    PubMed

    Ochi, Takehiro; Yamada, Azusa; Naganuma, Yuki; Nishina, Noriko; Koyama, Hironari

    2016-06-01

    To determine the effect of long-distance (approximately 600 km) road transportation on the blood biochemistry of laboratory animals, we investigated the changes in serum biochemical parameters in healthy cynomolgus monkeys and beagle dogs transported by truck from Osaka to Tsukuba, Japan. The concentrations of serum cortisol, total bilirubin and aspartate aminotransferase in monkeys increased during transportation. Serum cortisol and total bilirubin levels in dogs also increased during transportation, but serum triglyceride decreased. Serum parameter values in truck-transported monkeys and dogs returned to baseline levels within two weeks following arrival. Taken together, these results suggest that a two-week acclimation period is the minimum duration required for adaptation following road transportation.

  20. Automatic system for electron tomography data collection in the ultra-high voltage electron microscope.

    PubMed

    Cao, Meng; Nishi, Ryuji; Wang, Fang

    2017-09-12

    In this study, we report an automatic system for collection of tilt series for electron tomography based on the ultra-HVEM in Osaka University. By remotely controlling the microscope and reading the observation image, the system can track the field of view and do focus in each tilt angle. The automatic tracking is carried out with an image matching technique based on normalized correlation coefficient. Auto focus is realized by the optimization of image sharpness. A toolkit that can expand the field of view with technique of image stitching is also developed. The system can automatically collect the tilt series with much smaller time consumption. Copyright © 2017 Elsevier Ltd. All rights reserved.

  1. Fimbrial capture of the ovum and tubal transport of the ovum in the rabbit, with emphasis on the effects of beta 2-adrenoreceptor stimulant and prostaglandin F2 alpha on the intraluminal pressures of the tubal ampullae.

    PubMed

    Osada, H; Fujii, T K; Tsunoda, I; Takagi, K; Satoh, K; Kanayama, K; Endo, T

    1999-08-01

    Our purpose was to elucidate the roles of the ampullar and isthmic portions of the oviduct and the effects of drugs on oviductal contractility. Prostaglandin F2 alpha (PGF2 alpha; Ono Pharmaceuticals, Osaka) and oxytocin (Atonin-O; Teikoku Hormone Manufacturing Co. Ltd., Tokyo) were used to stimulate oviductal contractility, and ritodrine hydrochloride (Utemerin; Solvay-Duphar Corp., Denmark) to inhibit the contractility. Both PGF2 alpha and Atonin-O were involved in ovum capture by the ampullar oviduct by stimulating contractility, thus altering the intraductal pressures. Utemerin is effective in inhibiting the enhanced contractility induced by PGF2 alpha and Atonin-O. Variations in pressure of the ampullar portion of the oviduct seem necessary for the capture of ova expelled from the ovary. Once in the isthmic portion of the oviduct, transport appears to be under the influence of ciliary activity rather than variations in contractility.

  2. Effects of the irradiation of a finite number of laser beams on the implosion of a cone-guided target

    NASA Astrophysics Data System (ADS)

    Yanagawa, T.; Sakagami, H.; Nagatomo, H.; Sunahara, A.

    2016-03-01

    In direct drive laser fusion, the non-uniformity of the laser absorption on the target surface caused by the irradiation of a finite number of laser beams is a sever problem. GekkoXII laser at Osaka University has twelve laser beams and is irradiated to the target with a dodecahedron orientation, in which the distribution of the laser absorption on the target surface becomes non-uniform. Furthermore, in the case of a cone-guided target, the laser irradiation orientation is more limited. In this paper, we conducted implosion simulations of the cone- guided target based on GekkoXII irradiation orientation and compared the case of using the twelve beams and nine beams where the three beams irradiating the cone region are cut. The implosion simulations were conducted by a three-dimensional pure hydro code.

  3. Fabrication procedure for LiMn2O4/Graphite-based Lithium-ionRechargeable Pouch Cells

    SciTech Connect

    Liu, Gao; Zheng, Honghe; Battaglia, Vincent S.

    2007-04-30

    Procedures were developed at LBNL specifically for making electrodes and batteries of LiMn{sub 2}O{sub 4} (spinel) and MCMB (meso carbon micro beads) graphite for high-power applications (HEVs). Electrode performance can be very dependent on the materials used so it is pointed out that Toda M809 was used for the cathode active material and MCMB 10-28 from Osaka Gas was used for the anode active material. The conductive additives were Dankon black, an acetylene black, and SFG-6, a micron-size graphite. The binder used was PVdF (Kureha 1100). More details of these procedures can be found in the lab notebook of Gao Liu. These procedures are documented here but are continuously being refined, and should therefore be considered a work in progress.

  4. A Deep Morphological Characterization and Comparison of Different Dental Restorative Materials.

    PubMed

    Condò, R; Cerroni, L; Pasquantonio, G; Mancini, M; Pecora, A; Convertino, A; Mussi, V; Rinaldi, A; Maiolo, L

    2017-01-01

    Giomer is a relatively new class of restorative material with aesthetics, handling and physical properties of composite resins, and benefits of glass ionomers: high radiopacity, antiplaque effect, fluoride release, and recharge. To verify the superior properties of Giomers, in this study, a deep morphological characterization has been performed with an in vitro comparative study among a Giomer (Beautifil® II by Shofu Dental Corporation, Osaka, Japan), a Compomer (Dyract Extra by Dentsply, Caulk, Germany), glass ionomer cement (Ketac fil plus by 3M ESPE), and a composite resin (Tetric Evoceram by Ivoclar). In particular, mechanical and optical properties and ageing effects have been compared to investigate materials similarities and differences. Indentation tests, UV-Visible spectroscopy, Raman spectroscopy, and weight loss after storage in saliva or sugary drink have been carried out to analyze materials behavior in real conditions. The results confirm the high quality of Giomer material and indicate possible improvements in their usage.

  5. Measurements of Radiative Capture Cross Sections at Big Bang Energies

    NASA Astrophysics Data System (ADS)

    Tanaka, Masaomi; Fukuda, Mitsunori; Tanaka, Yutaro; Du, Hang; Ohnishi, Kousuke; Yagi, Shoichi; Sugihara, Takanobu; Hori, Taichi; Nakamura, Shoken; Yanagihara, Rikuto; Matsuta, Kensaku; Mihara, Mototsugu; Nishimura, Daiki; Iwakiri, Shuichi; Kambayashi, Shohei; Kunimatsu, Shota; Sakakibara, Hikaru; Yamaoka, Shintaro

    We measured d(p, γ )3He cross sections at ECM = 0.12, 0.19, 0.44, and 0.57 MeV. In this energy region, available experimental values are systematically smaller than the recent calculation, so that additional experiments are desired for understanding the Big Bang Nucleosynthesis. The experiment was performed by bombarding proton beams to the D2 gas target with the 5 MV Van de Graaff accelerator at Osaka University. The experimental d(p, γ )3He cross sections of the present study are systematically larger than previous data. On the other hand, recent theoretical results by Marcucci et al. are in good agreement with present experimental results.

  6. Organic Complexation of Fe in the Western Pacific During the 2002 IOC Expedition

    NASA Astrophysics Data System (ADS)

    Powell, R.; Donat, J. R.; Wilson-Finelli, A.; Morton, P.

    2002-12-01

    As part of a multi-investigator project, we participated in the 2002 IOC expedition from Osaka, Japan to Honolulu Hawaii. We collected 60 discrete samples from a clean towed fish (depth less than 1 m) for the determination of organic Fe complexing ligands and their associated conditional stability constants. The cruise track was designed to sample many distinct oceanographic regimes. These included, coastal, high nutrient low chlorophyll (HNLC), high atmospheric deposition, high Pb-210, and oligotrophic. We will present data from competitive ligand equilibration cathodic stripping voltammetry analyses that were conducted both at sea on fresh samples and back at the laboratory on frozen samples. We will contrast the various regimes with respect to concentrations of organic Fe complexing ligands, conditional stability constants, inorganic Fe and organic Fe concentrations. Preliminary results indicate significant differences between the higher latitude NNLC region and the more tropical waters near Hawaii with a greater excess and higher stability constant present in the HNLC region.

  7. Time-dependent density functional study on the photoisomerization mechanism of azobenzene

    NASA Astrophysics Data System (ADS)

    Oyama, Norihisa; Tateyama, Yoshitaka; Miyamoto, Yoshiyuki; Ohno, Takahisa

    2004-03-01

    Photochemical reactions in organic molecules have attracted considerable attention in semiconductor physics and also in bioscience. Azobenzene is a simple molecule which shows the reversible photoisomerization at high quantum yields, and can be used as a light-driven molecular switch and so on. However, the photoisomerization process of azobenzene is still an open question because of its femtosecond ultra-fast reaction. In this talk, we present time-dependent density functional calculations for the azobenzene molecule, and discuss the mechanism of photoisomerization induced by S1 and S2 excitations. This research is partially supported by ACT-JST, and also by FSIS and Special Coordination Funds of MEXT of Japanese Government. The calculations were carried out partly using the Numerical Materials Simulator in National Institute for Materials Science, and partly using the NEC-SX5 at Cybermedia Center of Osaka University.

  8. Developments of fast emittance monitors for ion sources at RCNP

    SciTech Connect

    Yorita, T. Hatanaka, K.; Fukuda, M.; Shimada, K.; Yasuda, Y.; Saito, T.; Tamura, H.; Kamakura, K.

    2016-02-15

    Recently, several developments of low energy beam transport line and its beam diagnostic systems have been performed to improve the injection efficiency of ion beam to azimuthally varying field cyclotron at Research Center for Nuclear Physics, Osaka University. One of those is the fast emittance monitor which can measure within several seconds for the efficient beam development and a Pepper-Pot Emittance Monitor (PPEM) has been developed. The PPEM consists of pepper-pot mask, multichannel plate, fluorescent screen, mirror, and CCD camera. The CCD image is taken via IEEE1394b to a personal computer and analyzed immediately and frequently, and then real time measurement with about 2 Hz has been achieved.

  9. Development of e-Learning Courses for Promoting Student's Global Competency-Basic Courses as a Guide to ESP Education in Advanced Science and Technology-

    NASA Astrophysics Data System (ADS)

    Nishikawa, Mikako; Nakajima, Mikio; Iwai, Chiharu; Ogasawara, Fumie; Kishino, Fumio; Fukui, Kiichi

    Osaka University has been chosen for the FY2005's “Selected Efforts of the Distinctive University Education Support Program (Gendai GP/Good Practice) ”by the Ministry of Education, Culture, Sports, Science and Technology (MEXT) . The aim of this project is to improve English proficiency of undergraduate students with scientific backgrounds. Under this strategic fund, e-Learning course contents were developed for instructing basic, yet practical English for Biotechnology during FY2005. Throughout the project, e-Learning contents will be developed for five other selected subjects of science i.e., 1) biotechnology, 2) information technology, 3) nano-technology, 4) environmental technology and 5) robotics technology, for undergraduate students as guiding courses to ESP education in graduate (higher) level.

  10. Operational experience of a large area x-ray camera for protein crystallography.

    SciTech Connect

    Joachimiak, A.; Jorden, A. R.; Loeffen, P. W.; Naday, I.; Sanishvili, R.; Westbrook, E. M.

    1999-07-13

    After 3 years experience of operating very large area (210mm x 210mm) CCD-based detectors at the Advanced Photon Source, operational experience is reported. Four such detectors have been built, two for Structural Biology Center (APS-1 and SBC-2), one for Basic Energy Sciences Synchrotrons Radiation Center (Gold-2) at Argonne National Laboratory's Advanced Photon Source and one for Osaka University by Oxford Instruments, for use at Spring 8 (PX-21O). The detector is specifically designed as a high resolution and fast readout camera for macromolecular crystallography. Design trade-offs for speed and size are reviewed in light of operational experience and future requirements are considered. Operational data and examples of crystallography data are presented, together with plans for more development.

  11. Accessibility condition of wave propagation and multicharged ion production in electron cyclotron resonance ion source plasma

    SciTech Connect

    Kato, Yushi Yano, Keisuke; Nishiokada, Takuya; Nagaya, Tomoki; Kimura, Daiju; Kumakura, Sho; Imai, Youta; Hagino, Shogo; Otsuka, Takuro; Sato, Fuminobu

    2016-02-15

    A new tandem type source of electron cyclotron resonance (ECR) plasmas has been constructing for producing synthesized ion beams in Osaka University. Magnetic mirror field configuration with octupole magnets can be controlled to various shape of ECR zones, namely, in the 2nd stage plasma to be available by a pair mirror and a supplemental coil. Noteworthy correlations between these magnetic configurations and production of multicharged ions are investigated in detail, as well as their optimum conditions. We have been considering accessibility condition of electromagnetic and electrostatic waves propagating in ECR ion source plasma, and then investigated their correspondence relationships with production of multicharged ions. It has been clarified that there exits efficient configuration of ECR zones for producing multicharged ion beams experimentally, and then has been suggested from detail accessibility conditions on the ECR plasma that new resonance, i.e., upper hybrid resonance, must have occurred.

  12. Estimating how and why Dr Okuda made a complete wooden human skeleton in the Edo era, Japan.

    PubMed

    Baba, Hisao

    2007-03-01

    Probably in 1820 (late Edo era), a human skeleton for medical education was precisely carved from cypress wood, based on a criminal's skeleton, by a craftsman under the supervision of the medical doctor Banri Okuda in Osaka City. By and large, the wooden skeleton shows morphological characteristics usually seen in early middle-aged females of the Edo era. However, the claviculae, distal ends of the femora and the patellae are exceptionally larger than those of a female, implying that the bones of the original model skeleton had already been lost or were deformed before the wooden skeleton was made. Furthermore, the skeleton may not have been used for medical education, but rather for the promotion of European medicine, which was gradually developing in the Edo era.

  13. The Development of the Multipolar Magnesium Cell: A Case History of International Cooperation in a Competitive World

    NASA Astrophysics Data System (ADS)

    Sivilotti, Olivo G.

    The author conceived the first multipolar magnesium electrolytic cell in the late 1970s, in order to offset the impact of an 80kA monopolar cell developed in cooperation with Osaka Titanium Company (OTC) being licensed by Alcan to a major competitor of OTC. During the 1980s the commercial value of the multipolar magnesium cell technology was established. The 1990s saw significant further progress by OTC, while attempts by Alcan to commercialize it in magnesium production plants met with technical difficulties and failure, due primarily to the lack of magnesium chloride feed of adequate quality. Now the author plans to commercialize a new multipolar cell design with a target productivity of 8-10 tons/day and a unit power consumption of 8.5-10 KWHR/kg of magnesium.

  14. From Extraction of Nucleon Resonances to LQCD

    SciTech Connect

    Lee, T.-S. H.; Wu, Jia-jun; Kamano, Hiroyuki

    2016-06-09

    The intrinsic difficulties in extracting the hadron resonances from reaction data are illustrated by using several exactly soluble ππ ππ scattering models. The finite-volume Hamiltonian method is applied to predict spectra using two meson-exchange Hamiltonians of πN πN reactions. Within a three-channel model with πN πN , πΔ πΔ and σN σN channels, we show the advantage of the finite-volume Hamiltonian method over the approach using the Lüscher formula to test Lattice QCD calculations aimed at predicting nucleon resonances. We discuss the necessary steps for using the ANL-Osaka eight-channel Hamiltonian to predict the spectra for testing the LQCD calculations for determining the excited nucleon states up to invariant mass W=2 W=2 GeV.

  15. Latest Advances in Plant Development and Environmental Response: The Inaugural Cold Spring Harbor Asia Plant Biology Meeting in Japan.

    PubMed

    Ikeuchi, Momoko; Rhodes, Jack

    2017-08-01

    With stunning ocean views over Osaka Bay, Awaji Island played host to the first Cold Spring Harbor Asia Plant Biology meeting in Japan. The meeting, 'Latest Advances in Plant Development and Environmental Response' (CSHAPB), provided a platform to promote scientific communication and collaboration in the pan-pacific region. The event welcomed almost 200 scientists from around the world to showcase their cutting-edge research. Exemplary speakers from diverse research fields presented their latest discoveries, ranging from developmental mechanisms to host-pathogen interactions, environmental responses and stress memory. Here we seek to review the meeting and highlight some of the salient themes that emerged over the course of the 3 d. © The Author 2017. Published by Oxford University Press on behalf of Japanese Society of Plant Physiologists. All rights reserved. For permissions, please email: journals.permissions@oup.com.

  16. SAFIR operation and evaluation of it's performance

    NASA Astrophysics Data System (ADS)

    Kawasaki, Z.-I.; Yamamoto, K.; Matsuura, K.; Richard, P.; Matsui, Toshiaki; Sonoi, Yasuo; Shimokura, Naoyoshi

    1994-06-01

    SAFIR (Surveillance et d'Alerte Foudre par Interferometrie Radioelectrique) has been equipped and operated in Japan since June 12th, 1991 as a cooperative project among Osaka University, Kansai Electric Power Co. INC.(KEPCO), and the French manufacturer DIMENSIONS. The operational coverage covers Northern Kinki District, Wakasa District, and Hokuriku District. Hokuriku District is well known for its winter thunderstorm activity. The method for the evaluation was to take the cross-correlation between the meteorological radar echo pattern and the distribution pattern of lightning discharges detected by SAFIR. We obtained high cross-correlation coefficients and concluded that the SAFIR locations were shown to have statistically high accuracy. We also show the case study of the occurrence of the lightning strike, which is recorded by KEPCO, to evaluate the usefulness of the warning by SAFIR.

  17. COG validation: SINBAD Benchmark Problems

    SciTech Connect

    Lent, E M; Sale, K E; Buck, R M; Descalle, M

    2004-02-23

    We validated COG, a 3D Monte Carlo radiation transport code, against experimental data and MNCP4C simulations from the Shielding Integral Benchmark Archive Database (SINBAD) compiled by RSICC. We modeled three experiments: the Osaka Nickel and Aluminum sphere experiments conducted at the OKTAVIAN facility, and the liquid oxygen experiment conducted at the FNS facility. COG results are in good agreement with experimental data and generally within a few % of MCNP results. There are several possible sources of discrepancy between MCNP and COG results: (1) the cross-section database versions are different, MCNP uses ENDFB VI 1.1 while COG uses ENDFB VIR7, (2) the code implementations are different, and (3) the models may differ slightly. We also limited the use of variance reduction methods when running the COG version of the problems.

  18. Laser implosion fusion

    SciTech Connect

    Yamanaka, C.

    1983-12-01

    The Institute of Laser Engineering at Osaka University outlines key issues of research, which are: the development of high-power drivers, pertinent pellet design for implosion by a large-scale computer code, pellet fabrication and handling, and diagnostic of the implosion process, with high resolution in space and time. Experimental facilities such as the GEKKO series and the CO/sub 2/-laser LEKKO series are discussed. A table and illustrations show energy drivers, the GEKKO XII optical arrangement, and the glass laser system of GEKKO XII. Fundamental processes in laser-plasma coupling, scaling of implosion presure, and implosion of the pellet and Cannonball target are described and accompanied by illustrations and photographs. The KONGOH project and activities at the Electrochemical Laboratory present research and progress on target experiments.

  19. High-precision (p,t) reaction measurement to determine Ne18(α,p)Na21 reaction rates

    NASA Astrophysics Data System (ADS)

    Matic, A.; van den Berg, A. M.; Harakeh, M. N.; Wörtche, H. J.; Berg, G. P. A.; Couder, M.; Fisker, J. L.; Görres, J.; Leblanc, P.; O'Brien, S.; Wiescher, M.; Fujita, K.; Hatanaka, K.; Sakemi, Y.; Shimizu, Y.; Tameshige, Y.; Tamii, A.; Yosoi, M.; Adachi, T.; Fujita, Y.; Shimbara, Y.; Fujita, H.; Wakasa, T.; Hess, P. O.; Brown, B. A.; Schatz, H.

    2009-11-01

    x-ray bursts are identified as thermonuclear explosions in the outer atmosphere of accreting neutron stars. The thermonuclear runaway is fueled by the αp process that describes a sequence of (α,p) reactions triggered by the Ne18(α,p)Na21 breakout reaction from the hot CNO cycles. We studied the level structure of the compound nucleus Mg22 by measuring the Mg24(p,t)Mg22 reaction at the Grand Raiden spectrometer at Research Center for Nuclear Physics, Osaka. A large number of α-unbound states was identified and precise excitation energies were determined. Based on shell model and α-cluster model calculations we predict the level parameters for determining the stellar reaction rate of Ne18(α,p)Na21 for a wide temperature range. x-ray burst simulations have been performed to study the impact of the reaction on the x-ray burst luminosity.

  20. Thomson scattering measurement of a collimated plasma jet generated by a high-power laser system

    NASA Astrophysics Data System (ADS)

    Ishikawa, T.; Sakawa, Y.; Morita, T.; Yamaura, Y.; Kuramitsu, Y.; Moritaka, T.; Sano, T.; Shimoda, R.; Tomita, K.; Uchino, K.; Matsukiyo, S.; Mizuta, A.; Ohnishi, N.; Crowston, R.; Woolsey, N.; Doyle, H.; Gregori, G.; Koenig, M.; Michaut, C.; Pelka, A.; Yuan, D.; Li, Y.; Zhang, K.; Zhong, J.; Wang, F.; Takabe, H.

    2016-03-01

    One of the important and interesting problems in astrophysics and plasma physics is collimation of plasma jets. The collimation mechanism, which causes a plasma flow to propagate a long distance, has not been understood in detail. We have been investigating a model experiment to simulate astrophysical plasma jets with an external magnetic field [Nishio et al., EPJ. Web of Conferences 59, 15005 (2013)]. The experiment was performed by using Gekko XII HIPER laser system at Institute of Laser Engineering, Osaka University. We shot CH plane targets (3 mm × 3 mm × 10 μm) and observed rear-side plasma flows. A collimated plasma flow or plasma jet was generated by separating focal spots of laser beams. In this report, we measured plasma jet structure without an external magnetic field with shadowgraphy, and simultaneously measured the local parameters of the plasma jet, i.e., electron density, electron and ion temperatures, charge state, and drift velocity, with collective Thomson scattering.

  1. Program of Research Internship as Vocational Education

    NASA Astrophysics Data System (ADS)

    Okuyama, Masanori

    Program of Research Internship as Vocational Education has been carried out in Graduate School of Engineering Science, Osaka University last year. Agreement of the internship has been promoted by discussing plan, adjustment and practice for the graduate school students in the company. The company has proposed many research themes for students and explained the contents in the meeting. The students submitted the application forms including their desired theme, curriculum vitae, motivation, appeal and activity, and the company accepted the students as research students. The selected students experienced the internship research works in various research centers. The meeting for reporting the experiences was set, joined by the students, persons in charge of the internship in the company, university supervisors, dean, members of the internship committee and office workers. Resultantly, the students caught different and fresh impression for the internship research and were considered to be encouraged for the advanced study.

  2. Electric Dipole Polarizability of Ca48 and Implications for the Neutron Skin

    DOE PAGES

    Birkhan, J.; Miorelli, M.; Bacca, S.; ...

    2017-06-23

    The electric dipole strength distribution in 48Ca between 5 and 25 MeV has been determined at RCNP, Osaka, from proton inelastic scattering experiments at forward angles. Combined with photoabsorption data at higher excitation energy, this enables the rst extraction of the electric dipole polarizability D(48Ca) = 2:07(22) fm3. Remarkably, the dipole response of 48Ca is found to be very similar to that of 40Ca, consistent with a small neutron skin in 48Ca. The experimental results are in good agreement with ab initio calculations based on chiral e ective eld theory interactions and with state-of-the-art density-functional calculations, implying a neutron skinmore » in 48Ca of 0:14 - 0:20 fm.« less

  3. An extensive outbreak of staphylococcal food poisoning due to low-fat milk in Japan: estimation of enterotoxin A in the incriminated milk and powdered skim milk.

    PubMed Central

    Asao, T.; Kumeda, Y.; Kawai, T.; Shibata, T.; Oda, H.; Haruki, K.; Nakazawa, H.; Kozaki, S.

    2003-01-01

    An extensive outbreak of staphylococcal food poisoning occurred in Kansai district in Japan. As many as 13,420 cases frequently ingested dairy products manufactured by a factory in Osaka City. The main ingredient of these dairy products was powdered skim milk manufactured by a factory in Hokkaido. Staphylococcal enterotoxin A (SEA) (< or = 0.38 ng/ml) was detected in low-fat milk and approx. 3.7 ng/g in powdered skim milk. The total intake of SEA per capita was estimated mostly at approx. 20-100 ng. The assumed attack rate was considerably lower than those reported in previous outbreaks. SEA exposed at least twice to pasteurization at 130 degrees C for 4 or 2 s retained both immunological and biological activities, although it had been partially inactivated. The present outbreak was unusual in that the thermal processes had destroyed staphylococci in milk but SEA had retained enough activity to cause intoxication. PMID:12613743

  4. Land subsidence caused by ground water withdrawal in urban areas

    USGS Publications Warehouse

    Holzer, T.L.; Johnson, A.I.

    1985-01-01

    At least eight urban areas in the world have encountered significant economic impact from land subsidence caused by pumping of ground water from unconsolidated sediment. The areas, most of which are coastal, include Bangkok, Houston, Mexico City, Osaka, San Jose, Shanghai, Tokyo, and Venice. Flooding related to decreased ground elevation is the principal adverse effect of the subsidence. Lesser effects include regional tilting, well-casing failures, "rising" buildings, and ground failure or rupture. Subsidence of most of these urban areas began before the phenomenon was discovered and understood. Thus, the subsidence problems were unanticipated. Methods to arrest subsidence typically have included control of ground water pumping and development of surface water to offset the reductions of ground water pumping. Ground water recharge has also been practiced. Areas threatened by flooding have been protected by extensive networks of dikes and sea walls, locks, and pumping stations to remove storm runoff. ?? 1985 D. Reidel Publishing Company.

  5. Biodegradation of aniline and abundance of potential degraders in river waters

    SciTech Connect

    Goonewardena, N.; Nasu, M.; Okuda, A.; Tani, K.; Takubo, Y.; Kondo, M. )

    1992-03-01

    Total dissolved organic carbon (TOC), number of colony forming units (CFU), and total direct count (TDC) were compared to the biodegradation of aniline and the number of potential degraders in water samples from head waters to down stream of the Ina River and several other sites of rivers traversing Osaka city. The results indicate that aniline degrading populations of these various microbial communities exhibit different activities probably depending on the extent of adaptation to pollutants to which the microbes are exposed. The number of aniline degraders found in river water samples was in agreement with other parameters which were used to demonstrate the degree of pollution in river water even though higher biodegradability was evident in waters which show comparatively low TOC and CFU. These results suggest that biodegradation of aniline and enumeration of its potential degraders may serve as valuable indicators for the assessment of pollution in river waters.

  6. Shell model description of Gamow-Teller strengths in pf-shell nuclei

    NASA Astrophysics Data System (ADS)

    Kumar, Vikas; Srivastava, P. C.

    2016-06-01

    A systematic shell model description of the experimental Gamow-Teller transition strength distributions in 42Ti , 46Cr , 50Fe and 54Ni is presented. These transitions have been recently measured via β -decay of these T_z=-1 nuclei, produced in fragmentation reactions at GSI and also with (3He, t) charge-exchange (CE) reactions corresponding to T_z=+1 to T_z=0 carried out at RCNP-Osaka. The calculations are performed in the pf model space, using the GXPF1a and KB3G effective interactions. Qualitative agreement is obtained for the individual transitions, while the calculated summed transition strengths closely reproduce the observed ones.

  7. Seismic monitoring and real time damage estimation for lifelines

    SciTech Connect

    Takada, Shiro; Ogawa, Yasuo

    1995-12-31

    This paper presents a methodology for estimating the number of damaged locations of lifeline systems based on seismic monitoring ground motions taking consideration of liquefaction phenomena. The liquefaction area and the number of damage to the lifeline facilities can be synthetically indicated by a personal computer program developed for this purpose. The method is based on the real time observed data of strong ground motions. Osaka Gas Company had been developing the real time damage simulation system by planning to set additional tele-meter seismographs when the Hanshin Great Earthquake occurred. Other lifelines such as electricity, telecommunication, water and sewage systems in quake-hit area had not such a real time damage simulation tool based on observed ground motions. On the other hand, these lifelines have their own damage detection system such as pressure, flow, relay signal, etc.

  8. [Study of novel artificial lung surfactants incorporating partially fluorinated amphiphiles].

    PubMed

    Nakahara, Hiromichi

    2012-01-01

    Lung surfactants (LS), a complex of ∼90 wt% lipids (mainly dipalmitoylphosphatidylcholine or DPPC) and ∼10 wt% surfactant proteins (SP-A, -B, -C, and -D), adsorb to an air-alveolar fluid interface and then lower its surface tension down to near zero during expiration. Intratracheal instillation of exogenous LS preparations can effectively compensate for surfactant deficiency in premature infants with respiratory distress syndrome (RDS). Surfacten® (Mitsubishi Tanabe Pharma Corporation, Osaka, Japan), a modified bovine lung extract and an effective surfactant replacement in treatment for RDS patients, is supplemented with DPPC, palmitic acid, and tripalmitin. For the premature infants suffering from RDS, instillation of Surfacten® leads to a dramatic improvement in lung function and compliance. Herein, the author reviews potential use of newly designed preparations containing a mimicking peptide of SP-B and also introduces the current research on the preparations incorporated with partially fluorinated amphiphiles to improve their efficacy.

  9. High-speed x-ray radiographic measurement of laser-driven hydrodynamic instability

    NASA Astrophysics Data System (ADS)

    Shiraga, Hiroyuki; Azechi, Hiroshi; Nakai, Mitsuo; Shigemori, Keisuke; Nishikino, Masaharu; Sakaiya, Tatsuhiro; Fujioka, Shinsuke; Tamari, Yohei; Yamanaka, Tatsuhiko

    2003-07-01

    Hydrodynamic instability in laser-irradiated targets have been investigated in detail by using ultra high-speed x-ray radiographic technique. Recently developed high-resolution x-ray imaging for laser-driven Rayleigh-Taylor (RT) instability experiments as well as data including RT growth rate, ablation density and plasma density profile are desribed. Results are of great importance for comprehensive understanding of the dispersion relation of the laser-driven RT instability. Especially, direct observation of the ablation density was first achieved with temporal and spatial resolutions of 100 ps and 3 μm, respectively. Imaging techniques includes x-ray Moire imaging, x-ray penumbral imaging and Fresnel phase zone plate imaging coupled with x-ray streak cameras or x-ray CCD cameras. Experiments were performed by using Gekko-XII/HIPER laser system at the Institute of Laser Engineering, Osaka University.

  10. COMMITTEES: Proceedings of the 13th Gravitational Waves Data Analysis Workshop (GWDAW13), San Juan, Puerto Rico, 19-22 January 2009 Proceedings of the 13th Gravitational Waves Data Analysis Workshop (GWDAW13), San Juan, Puerto Rico, 19-22 January 2009

    NASA Astrophysics Data System (ADS)

    2009-10-01

    Science Organising Committee (SOC) Bruce Allen, AEI, Germany Patrick Brady, University of Wisconsin Milwaukee, USA Deepto Chakrabarty, MIT, USA Eugenio Coccia, INFN, Gran Sasso, Italy James Cordes, Cornell University, USA Mario Díaz (Chair), University of Texas Brownsville, USA Sam Finn, Penn State, USA Neil Gehrels, NASA GSFC, USA Fredrick A Jenet, University of Texas Brownsville, USA Nobuyuki Kanda, Osaka City University, Japan Erik Katsavounides, MIT, USA Dick Manchester, ATNF, Australia Soumya Mohanty, University of Texas Brownsville, USA Benoit Mours, LAPP-Annecy, France Maria Alessandra Papa, AEI, Germany Kate Scholberg, Duke University, USA Susan Scott, The Australian National University Alberto Vecchio, University of Birmingham, UK Andrea Vicere, INFN - Sezione di Firenze, Italy Stan Whitcomb, LIGO CALTECH, USA Local Organising Committee (LOC) Paulo Freire (Arecibo Observatory, Puerto Rico) Murray Lewis (Arecibo Observatory, Puerto Rico) Wanda Wiley (University of Texas Brownsville, USA)

  11. Lower Physical Performance in Colder Seasons and Colder Houses: Evidence from a Field Study on Older People Living in the Community

    PubMed Central

    Hayashi, Yukie; Schmidt, Steven M.; Malmgren Fänge, Agneta; Hoshi, Tanji; Ikaga, Toshiharu

    2017-01-01

    The aim of this paper was to explore the effect of seasonal temperature differences and cold indoor environment in winter on the physical performance of older people living in the community based on a field study. We recruited 162 home-dwelling older people from a rehabilitation facility in the Osaka prefecture, Japan; physical performance data were available from 98/162 (60.5%). At the same time, for some participants, a questionnaire survey and a measurement of the indoor temperature of individual houses were conducted. The analysis showed that there were seasonal trends in the physical performance of older people and that physical performance was worse in the winter compared with the autumn. Furthermore, people living in colder houses had worse physical performance. The findings indicate that keeping the house warm in the winter can help to maintain physical performance. PMID:28629127

  12. Lower Physical Performance in Colder Seasons and Colder Houses: Evidence from a Field Study on Older People Living in the Community.

    PubMed

    Hayashi, Yukie; Schmidt, Steven M; Malmgren Fänge, Agneta; Hoshi, Tanji; Ikaga, Toshiharu

    2017-06-17

    The aim of this paper was to explore the effect of seasonal temperature differences and cold indoor environment in winter on the physical performance of older people living in the community based on a field study. We recruited 162 home-dwelling older people from a rehabilitation facility in the Osaka prefecture, Japan; physical performance data were available from 98/162 (60.5%). At the same time, for some participants, a questionnaire survey and a measurement of the indoor temperature of individual houses were conducted. The analysis showed that there were seasonal trends in the physical performance of older people and that physical performance was worse in the winter compared with the autumn. Furthermore, people living in colder houses had worse physical performance. The findings indicate that keeping the house warm in the winter can help to maintain physical performance.

  13. Kinematics of Selected Planck Galactic Cold Clumps

    NASA Astrophysics Data System (ADS)

    Varga-Verebélyi, E.; Tóth, L. V.; Marton, G.; Marshall, D.; Dobashi, K.; Shimoikura, T.

    We have completed a kinematical analysis of 184 selected Planck Galactic Cold Clumps (PGCC) (Planck Collaboration, 2015) in order to understand better the stability of molecular clouds and the induced star formations. Most of our clumps are in the second quadrant of the Galaxy. For the investigation we used 12CO, 13CO, C18O line observations which covered the 184 PGCC fully or partially. The majority of the data were observed with the Osaka 1.85 m telescope in Japan (Nishimura et al. 2015) and we also have some observations with the KOSMA 3 m telescope, from Switzerland (Kramer et al. 2000) and with the IRAM 30 m telescope, Spain (www.iram-institute.org).

  14. Progress toward a unified kJ-machine CANDY

    NASA Astrophysics Data System (ADS)

    Kitagawa, Yoneyoshi; Mori, Yoshitaka; Komeda, Osamu; Hanayama, Ryohei; Ishii, Katsuhiro; Okihara, Shinichiro; Fujita, Kazuhisa; Nakayama, Suisei; Sekine, Takashi; Sato, Nakahiro; Kurita, Takashi; Kawashima, Toshiyuki; Watari, Takeshi; Kan, Hirofumi; Nakamura, Naoki; Kondo, Takuya; Fujine, Manabu; Azuma, Hirozumi; Motohiro, Tomoyoshi; Hioki, Tatsumi; Kakeno, Mitsutaka; Nishimura, Yasuhiko; Sunahara, Atsushi; Sentoku, Yasuhiko; Miura, Eisuke; Arikawa, Yasunobu; Nagai, Takahiro; Abe, Yuki; Ozaki, Satoshi; Noda, Akira

    2016-03-01

    To construct a unified experimental machine CANDY using a kJ DPSSL driver in the fast-ignition scheme, the Laser for Fast Ignition Experiment (LFEX) at Osaka is used, showing that the laser-driven ions heat the preimploded core of a deuterated polystyrene (CD) shell target from 0.8 keV to 2 keV, resulting in 5 x 108 DD neutrons best ever obtained in the scheme. 4-J/10-Hz DPSSL laser HAMA is for the first time applied to the CD shell implosion- core heating experiments in the fast ignition scheme to yield neutrons and also to a continuous target injection, which yields neutrons of 3 x 105 n/4πsr n/shot.

  15. Hugoniot and mean ionization of laser-shocked Ge-doped plastic

    SciTech Connect

    Huser, G.; Salin, G.; Galmiche, D.; Ozaki, N.; Kodama, R.; Sano, T.; Sakawa, Y.; Miyanishi, K.; Asaumi, Y.; Kita, M.; Kondo, Y.; Nakatsuka, K.; Uranishi, H.; Yang, T.; Yokoyama, N.

    2013-12-15

    Pressure, density, temperature, and reflectivity measurements along the principal Hugoniot of Ge-doped plastics used in Inertial Confinement Fusion capsules surrogates were obtained to pressures reaching up to 7 Mbar and compared to Quotidian Equation of State models. The experiment was performed using the GEKKO XII laser at the Institute of Laser Engineering at Osaka University in Japan. High precision measurements of pressure and density were obtained using a quartz standard and found to be in good agreement with theoretical Hugoniot curves. Modeling of reflectivity measurements show that shocked samples can be described as poor metals and that mean ionization calculated within the frame of QEOS is overestimated. Similarly, shock temperatures were found to be below theoretical Hugoniot curves.

  16. Electric Dipole Polarizability of 48Ca and Implications for the Neutron Skin

    NASA Astrophysics Data System (ADS)

    Birkhan, J.; Miorelli, M.; Bacca, S.; Bassauer, S.; Bertulani, C. A.; Hagen, G.; Matsubara, H.; von Neumann-Cosel, P.; Papenbrock, T.; Pietralla, N.; Ponomarev, V. Yu.; Richter, A.; Schwenk, A.; Tamii, A.

    2017-06-01

    The electric dipole strength distribution in 48Ca between 5 and 25 MeV has been determined at RCNP, Osaka from proton inelastic scattering experiments at forward angles. Combined with photoabsorption data at higher excitation energy, this enables the first extraction of the electric dipole polarizability αD(48Ca)=2.07 (22 ) fm3 . Remarkably, the dipole response of 48Ca is found to be very similar to that of 40Ca, consistent with a small neutron skin in 48Ca. The experimental results are in good agreement with ab initio calculations based on chiral effective field theory interactions and with state-of-the-art density-functional calculations, implying a neutron skin in 48Ca of 0.14-0.20 fm.

  17. Direct heating of imploded plasma in the fast ignition

    NASA Astrophysics Data System (ADS)

    Sunahara, Atsushi; Johzaki, Tomoyuki; Nagatomo, Hideo; Mima, Kunioki; Shiraga, Hiroyuki; Azechi, Hiroshi; Mori, Yohitaga; Kitagawa, Yoneyoshi

    2016-03-01

    We propose the direct heating of an imploded plasma core by ultra-intense lasers in inertial confinement fusion, to increase the heating coupling efficiency. In this scheme, both fast-electrons and fast-ions heat the plasma core. Experiments using this direct heating scheme has been carried out at GXII and LFEX laser facility at Osaka Univeristy. To model this direct heating scheme, we developed the 1D simulation model and carried out simulations using the experimental conditions. Comparison between results of the simulation and the experimental observations validates the simulation model. We show that even in the unoptimized experimental conditions used in simulations, our calculations show that the maximum temperature, 1.6 keV, of the CD plasma.

  18. Ballistic Characterization of the Scalability of Mg Alloy AMX602

    NASA Astrophysics Data System (ADS)

    Jones, Tyrone L.; Kondoh, Katsuyoshi; Moore, David; Otsuka, Isamu; Annis, Alan; Nakazawa, Hiroto; Ohori, Yoshinori; Numasawa, Ryo; Takahashi, Masamichi

    The US Army Research Laboratory (ARL) and the Osaka University Joining and Welding Research Institute (JWRI) formed a collaborative partnership with Taber Extrusions, Epson, Pacific Sowa, Kurimoto, and National Material LP to domestically reproduce and scale-up military grade magnesium alloy AMX602 at the Taber Extrusion manufacturing facility in Gulfport, MS. AMX602 material was provided in the form of 38.1-mm (1.5-inch) wide bars, 101.6-mm (4-inch) wide plate, and 152.4-mm (6-in) wide plate. The ARL and the JWRI conducted mechanical analysis and dynamic impact examination to evaluate the lateral dimension scale-up of AMX602. The results were parametrically analyzed and compared to conventionally processed AZ31B-H24 and AA5083-H131. Details of the scalability of the AMX602 alloy are provided.

  19. Experimental and ab initio investigations of microscopic properties of laser-shocked Ge-doped ablator

    NASA Astrophysics Data System (ADS)

    Huser, G.; Recoules, V.; Ozaki, N.; Sano, T.; Sakawa, Y.; Salin, G.; Albertazzi, B.; Miyanishi, K.; Kodama, R.

    2015-12-01

    Plastic materials (CH) doped with mid-Z elements are used as ablators in inertial confinement fusion (ICF) capsules and in their surrogates. Hugoniot equation of state (EOS) and electronic properties of CH doped with germanium (at 2.5% and 13% dopant fractions) are investigated experimentally up to 7 Mbar using velocity and reflectivity measurements of shock fronts on the GEKKO laser at Osaka University. Reflectivity and temperature measurements were updated using a quartz standard. Shocked quartz reflectivity was measured at 532 and 1064 nm. Theoretical investigation of shock pressure and reflectivity was then carried out by ab initio simulations using the quantum molecular dynamics (QMD) code abinit and compared with tabulated average atom EOS models. We find that shock states calculated by QMD are in better agreement with experimental data than EOS models because of a more accurate description of ionic structure. We finally discuss electronic properties by comparing reflectivity data to a semiconductor gap closure model and to QMD simulations.

  20. From Extraction of Nucleon Resonances to LQCD

    NASA Astrophysics Data System (ADS)

    Lee, T.-S. H.; Wu, Jia-jun; Kamano, Hiroyuki

    2016-10-01

    The intrinsic difficulties in extracting the hadron resonances from reaction data are illustrated by using several exactly soluble π π scattering models. The finite-volume Hamiltonian method is applied to predict spectra using two meson-exchange Hamiltonians of π N reactions. Within a three-channel model with π N, π Δ and σ N channels, we show the advantage of the finite-volume Hamiltonian method over the approach using the Lüscher formula to test Lattice QCD calculations aimed at predicting nucleon resonances. We discuss the necessary steps for using the ANL-Osaka eight-channel Hamiltonian to predict the spectra for testing the LQCD calculations for determining the excited nucleon states up to invariant mass W= 2 GeV.

  1. Search for the Rare γ-Decay Mode in 12C

    NASA Astrophysics Data System (ADS)

    Tsumura, Miho; Kawabata, Takahiro

    In the normal stellar temperature, the triple α process proceeds via the 02 + state (Hoyle states) at Ex = 7.65 MeV in 12C. At high temperature T > 109 K, highly excited 3α resonance states such as the 31 - state at Ex = 9.64 MeV might play a part of the triple α reaction. However, their γ-decay probabilities have not been determined. We plan to study the 1H(12C, 12Cp) reaction through states higher than 02 + without measuring γ-rays. A test experiment using a solid hydrogen target and GAGG (Gd3Al2Ga3O12) scintillators was recently carried out at the cyclotron facility in RCNP, Osaka University. Its results are reported.

  2. Accessibility condition of wave propagation and multicharged ion production in electron cyclotron resonance ion source plasma

    NASA Astrophysics Data System (ADS)

    Kato, Yushi; Yano, Keisuke; Nishiokada, Takuya; Nagaya, Tomoki; Kimura, Daiju; Kumakura, Sho; Imai, Youta; Hagino, Shogo; Otsuka, Takuro; Sato, Fuminobu

    2016-02-01

    A new tandem type source of electron cyclotron resonance (ECR) plasmas has been constructing for producing synthesized ion beams in Osaka University. Magnetic mirror field configuration with octupole magnets can be controlled to various shape of ECR zones, namely, in the 2nd stage plasma to be available by a pair mirror and a supplemental coil. Noteworthy correlations between these magnetic configurations and production of multicharged ions are investigated in detail, as well as their optimum conditions. We have been considering accessibility condition of electromagnetic and electrostatic waves propagating in ECR ion source plasma, and then investigated their correspondence relationships with production of multicharged ions. It has been clarified that there exits efficient configuration of ECR zones for producing multicharged ion beams experimentally, and then has been suggested from detail accessibility conditions on the ECR plasma that new resonance, i.e., upper hybrid resonance, must have occurred.

  3. Gamma Strength Functions and Level Densities from 300 MeV Proton Scatttering at 0°

    NASA Astrophysics Data System (ADS)

    von Neumann-Cosel, Peter; Bassauer, Sergej; Martin, Dirk

    The gamma strength function (GSF) as well as total level densities (LDs) in 208Pb and 96Mo were extracted from high-resolution forward angle inelastic proton scattering data taken at RCNP, Osaka, Japan, and compared to experimental results obtained with the Oslo method in order to test the validity of the Brink-Axel (BA) hypothesis in the energy region of the pygmy dipole resonance. The case of 208Pb is inconclusive because of strong fluctuations of the GSF due to the small level density in a doubly closed-shell nucleus. In 96Mo the data are consistent with the BA hypothesis. The good agreement of LDs provides an independent confirmation of the approach underlying the decomposition of GSF and LDs in Oslo-type experiments.

  4. Developments of fast emittance monitors for ion sources at RCNP

    NASA Astrophysics Data System (ADS)

    Yorita, T.; Hatanaka, K.; Fukuda, M.; Shimada, K.; Yasuda, Y.; Saito, T.; Tamura, H.; Kamakura, K.

    2016-02-01

    Recently, several developments of low energy beam transport line and its beam diagnostic systems have been performed to improve the injection efficiency of ion beam to azimuthally varying field cyclotron at Research Center for Nuclear Physics, Osaka University. One of those is the fast emittance monitor which can measure within several seconds for the efficient beam development and a Pepper-Pot Emittance Monitor (PPEM) has been developed. The PPEM consists of pepper-pot mask, multichannel plate, fluorescent screen, mirror, and CCD camera. The CCD image is taken via IEEE1394b to a personal computer and analyzed immediately and frequently, and then real time measurement with about 2 Hz has been achieved.

  5. Ballistic Analysis of New Military Grade Magnesium Alloys for Armor Applications

    NASA Astrophysics Data System (ADS)

    Jones, Tyrone L.; Kondoh, Katsuyoshi

    Since 2006, the U.S. Army has been evaluating magnesium (Mg) alloys for ballistic structural applications. While Mg-alloys have been used in military structural applications since WWII, very little research has been done to improve its mediocre ballistic performance. The Army's need for ultra-lightweight armor systems has led to research and development of high strength, high ductility Mg-alloys. The U.S. Army Research Laboratory contracted through International Technology Center-Pacific Contract Number FA-5209-09-P-0158 with the Joining and Welding Research Instituteof Osaka University to develop the next generation of high strength, high ductility Mg-alloys using a novel Spinning Water Atomization Process for rapid solidification. New alloys AMX602 and ZAXE1711 in extruded bar form were characterized for microstructure, mechanical, and ballistic response. Significant increases in ballistic performance were evident when compared to the baseline alloy AZ31B.

  6. Evidence of tensor interactions in 16O observed via (p,d) reaction

    NASA Astrophysics Data System (ADS)

    Ong, H. J.; Tanihata, I.; Tamii, A.; Myo, T.; Ogata, K.; Fukuda, M.; Hirota, K.; Ikeda, K.; Ishikawa, D.; Kawabata, T.; Matsubara, H.; Matsuta, K.; Mihara, M.; Naito, T.; Nishimura, D.; Ogawa, Y.; Okamura, H.; Ozawa, A.; Pang, D. Y.; Sakaguchi, H.; Sekiguchi, K.; Suzuki, T.; Taniguchi, M.; Takashina, M.; Toki, H.; Yasuda, Y.; Yosoi, M.; Zenihiro, J.

    2014-03-01

    We measured the differential cross sections of the 16O(p,d) reaction populating the ground state and several low-lying excited states in 15O using 198-, 295- and 392-MeV proton beams at the Research Center for Nuclear Physics (RCNP), Osaka University, to study the effect of the tensor interactions in 16O. Dividing the cross sections for each excited state by the one for the ground state and comparing the ratios over a wide range of momentum transfer, we found a marked enhancement of the ratio for the positive-parity state(s). The observation is consistent with large components of high-momentum neutrons in the ground-state configurations of 16O due possibly to the tensor interactions.

  7. Constraining the density slope of nuclear symmetry energy at subsaturation densities using electric dipole polarizability in 208Pb

    NASA Astrophysics Data System (ADS)

    Zhang, Zhen; Chen, Lie-Wen

    2014-12-01

    Nuclear structure observables usually most effectively probe the properties of nuclear matter at subsaturation densities rather than at saturation density. We demonstrate that the electric dipole polarizibility αD in 208Pb is sensitive to both the magnitude Esym(ρc) and density slope L (ρc) of the symmetry energy at the subsaturation cross density ρc=0.11 fm-3. Using the experimental data of αD in 208Pb from RCNP (Research Center for Nuclear Physics, Osaka University) and the recent accurate constraint of Esym(ρc) from the binding energy difference of heavy isotope pairs, we extract a value of L (ρc)=47.3 ±7.8 MeV. The implication of the present constraint of L (ρc) to the symmetry energy at saturation density, the neutron skin thickness of 208Pb and the core-crust transition density in neutron stars is discussed.

  8. Measurements of Cross Sections for Neutron-induced Reactions on Chromium and Yttrium Targets at 197 MeV

    NASA Astrophysics Data System (ADS)

    Sekimoto, S.; Suzuki, H.; Yashima, H.; Ninomiya, K.; Kasamatsu, Y.; Shima, T.; Takahashi, N.; Shinohara, A.; Matsumura, H.; Hagiwara, M.; Nishiizumi, K.; Caffee, M. W.; Shibata, S.

    2014-05-01

    Reaction cross sections for Cr and Y induced by neutrons at 197 MeV were measured by using 7Li(p,n) reaction at N0 beam line in the Research Center for Nuclear Physics (RCNP), Osaka University. To estimate quasi-monoenergetic neutron cross sections, Cr and Y samples were irradiated on the two angles of 0∘ and 25∘ relative to the axis of the primary proton beam. The measured cross section data in the natCr(n,x) and 89Y(n,x) reactions are compared to the JENDL high-energy file and the literature proton values, respectively. The results obtained are also compared to the cross section data for the same target materials with 287 and 386 MeV neutrons in our previous work.

  9. Proving diamonds under ultra-high pressure with sound velocity measurements

    NASA Astrophysics Data System (ADS)

    Shigemori, Keisuke; Shimizu, Katsuya; Asakura, Yasuhiro; Sakaiya, Tatsuhiro; Kondo, Tadashi; Hironaka, Yoichiro; Irifune, Tetsuo; Sumiya, Hitoshi; Kadono, Toshihiko; Azechi, Hiroshi

    2014-10-01

    Diamond under terapascal (TPa) regime is of great interest on its phase transition to a post diamond phase. Many experimental works have been done on the diamond at the TPa regime by measuring the shock parameters (shock velocity, particle velocity). We measured sound velocities of shock-compressed diamond under several pressures by means of x-ray backlighting technique. Experiments were done on GEKKO-HIPER laser irradiation facility at Institute of Laser Engineering, Osaka University. We obtained sound velocities at a pressure of 0.4 - 2.0 TPa by changing the laser intensity. The experimental sound velocity suggests that a clear discontinuity at around 0.7 TPa where the melting of the diamond starts. The sound velocity drops then slightly increases with increasing pressure. The slope of the sound velocity over 1 TPa is lower than that under 0.7 TPa, indicating the melting of the diamond.

  10. Image reconstruction method for non-synchronous THz signals

    NASA Astrophysics Data System (ADS)

    Oda, Naoki; Okubo, Syuichi; Sudou, Takayuki; Isoyama, Goro; Kato, Ryukou; Irizawa, Akinori; Kawase, Keigo

    2014-05-01

    Image reconstruction method for non-synchronous THz signals was developed for a combination of THz Free Electron Laser (THz-FEL) developed by Osaka University with THz imager. The method employs a slight time-difference between repetition period of THz macro-pulse from THz-FEL and a plurality of frames for THz imager, so that image can be reconstructed out of a predetermined number of time-sequential frames. This method was applied to THz-FEL and other pulsed THz source, and found very effective. Thermal time constants of pixels in 320x240 microbolometer array were also evaluated with this method, using quantum cascade laser as a THz source.

  11. Hugoniot and mean ionization of laser-shocked Ge-doped plastic

    NASA Astrophysics Data System (ADS)

    Huser, G.; Ozaki, N.; Sano, T.; Sakawa, Y.; Miyanishi, K.; Salin, G.; Asaumi, Y.; Kita, M.; Kondo, Y.; Nakatsuka, K.; Uranishi, H.; Yang, T.; Yokoyama, N.; Galmiche, D.; Kodama, R.

    2013-12-01

    Pressure, density, temperature, and reflectivity measurements along the principal Hugoniot of Ge-doped plastics used in Inertial Confinement Fusion capsules surrogates were obtained to pressures reaching up to 7 Mbar and compared to Quotidian Equation of State models. The experiment was performed using the GEKKO XII laser at the Institute of Laser Engineering at Osaka University in Japan. High precision measurements of pressure and density were obtained using a quartz standard and found to be in good agreement with theoretical Hugoniot curves. Modeling of reflectivity measurements show that shocked samples can be described as poor metals and that mean ionization calculated within the frame of QEOS is overestimated. Similarly, shock temperatures were found to be below theoretical Hugoniot curves.

  12. Effect of tensor interactions in 16O studied via (p,d) reaction

    NASA Astrophysics Data System (ADS)

    Ong, H. J.; Tanihata, I.; Tamii, A.; Myo, T.; Ogata, K.; Fukuda, M.; Hirota, K.; Ikeda, K.; Ishikawa, D.; Kawabata, T.; Matsubara, H.; Matsuta, K.; Mihara, M.; Naito, T.; Nishimura, D.; Ogawa, Y.; Ozawa, A.; Pang, D. Y.; Sakaguchi, H.; Sekiguchi, K.; Suzuki, T.; Taniguchi, M.; Takashina, M.; Toki, H.; Yasuda, Y.; Yosoi, M.; Zenihiro, J.

    2014-12-01

    The differential cross sections of the 16O(p,d) reaction populating the ground state and several low-lying excited states in 15O were measured using 198-, 295- and 392-MeV proton beams at the Research Center for Nuclear Physics (RCNP), Osaka University, to study the effect of the tensor interactions in 16O. Dividing the cross sections for each excited state by the one for the ground state and comparing the ratios over a wide range of momentum transfer, we found a marked enhancement of the ratio for the positive-parity state(s). The observation is consistent with large components of high-momentum neutrons in the ground-state configurations of 16O due possibly to the tensor interactions.

  13. Effect of Tensor Interactions in 16O Studied via (p,d) Reaction

    NASA Astrophysics Data System (ADS)

    Ong, H. J.; Tanihata, I.; Tamii, A.; Myo, T.; Ogata, K.; Fukuda, M.; Hirota, K.; Ikeda, K.; Ishikawa, D.; Kawabata, T.; Matsubara, H.; Matsuta, K.; Mihara, M.; Naito, T.; Nishimura, D.; Ogawa, Y.; Ozawa, A.; Pang, D. Y.; Sakaguchi, H.; Sekiguchi, K.; Suzuki, T.; Taniguchi, M.; Takashina, M.; Toki, H.; Yasuda, Y.; Yosoi, M.; Zenihiro, J.

    We report a study on the effect of the tensor interactions in 16O via the (p,d) reaction using proton beams at 198, 295, and 392 MeV at the Research Center for Nuclear Physics (RCNP), Osaka University. Differential cross sections populating the ground state and several low-lying excited states in 15O were measured. Dividing the cross sections for each excited state by the one for the ground state and comparing the ratios over a wide range of momentum transfer, we found a marked enhancement of the ratio for the 5/2+ and/or 1/2+ state(s). The observation indicates large components of high-momentum neutrons in the ground-state configurations of 16O due possibly to the tensor interactions.

  14. Results of Education Program of “Training of Designers for Town Renovation”

    NASA Astrophysics Data System (ADS)

    Nitta, Yasutsugu; Inoi, Hiroto

    The paper introduces the outline and results of the education program of “Training of designers for town renovation”, which has been done for two years in Osaka University, sponsored by the Ministry of education, culture, sports, science and technology. The program has three main aims as follows ; to understand three factors of town planning, “Shape”, “System” and “Mind” and master the design skills for realizing three factors, to master the design skills integrating three factors which are “Environment”, “Social” and “Economic”, and to perceive various people living, improve the ability of communicating and enhance the desire of participating town planning process.

  15. High-technology ceramics for Japanese heat engines

    SciTech Connect

    Kamo, R.

    1984-01-01

    Japan's new ceramic age is providing the impetus for developing new materials for heat engine applications. A strategy developed by the Japanese Ministry of International Trade and Industry (MITI), universities, and industry has led to developments that make Japan competitive. The author describes the functions and levels of effort as well as the funding arrangements for two basic MITI projects: Moonlight Project and Industrial Base Technology Development Project. He concludes that a solution of the problems associated with ceramic heat engines will lead to a low-cost, waterless and oilless engine with high thermal efficiency. US technology is currently superior except for the high temperature-high strength ceramic materials. Three government research laboratories in Nagoya, Osaka, and Kyushu also work together with private and industrial laboratories. 17 references, 7 figures, 6 tables.

  16. Complete dipole strength distributions in 208Pb from high-resolution polarized proton scattering at 0°

    NASA Astrophysics Data System (ADS)

    von Neumann-Cosel, Peter

    2012-02-01

    Small-angle polarized proton scattering including 0° at incident energies of a few 100 MeV/nucleon is established as a new spectrospcopic tool for the study of E1 and M1 strength distributions. Experiments of this type have been realized recently at RCNP, Osaka, Japan with high energy resolution of the order 25 - 30 keV (FWHM). Using 208Pb as an example, the physics potential of such data is discussed. It includes information on the properties of the Pygmy Dipole Resonance but also on complete E1 and M1 strength distributions and thus the gamma strength function. The E1 polarizability can be extracted with a precision of about 4% providing important experimental constraints on the neutron skin thickness in 208Pb.

  17. [Historical study of a moth repellent "Fujisawa Camphor" (4) - newspaper advertisements for "Fujisawa Camphor" in the Meiji Era].

    PubMed

    Hattori, Akira

    2004-01-01

    Newspaper advertisements were frequently available as one way of communicating news about new products to the general public during the middle of the Meiji Era. The first newspaper advertisement of "Fujisawa Camphor"' appeared in the Osaka Asahi on June 1, 1989. At that time, the newspaper advertisements of OTC were brilliant and the space taken by them was large, in some cases covering a full page. They appeared daily. However, the ad for Fujisawa Camphors was small and simple. The appeal points of the Fujisawa Camphor advertisement were as follows: 1. Fujisawa Camphor, crystals of refined camphor, are hard and colorless.2. It is effective for insecticide and prevents moisture.3. It is widely used by governments and the military.4. It removes bad smell to protect against infectious diseases.

  18. The progress in the neutron diagnostics in the Fast Ignition experiment with GEKKO XII and LFEX

    NASA Astrophysics Data System (ADS)

    Arikawa, Yasunobu; Nagai, Takahiro; Abe, Yuki; Kojima, Sadaoki; Sakata, Shohei; Inoue, Hiroaki; Fujioka, Shinsuke; Sarukura, Nobuhiko; Nakai, Mitsuo; Shiraga, Hiroyuki; Azechi, Hiroshi

    2012-10-01

    In the fast ignitor experiment the neutron diagnostics is very challenging due to too large backgrounds originated from hard X ray. In the Fast Ignition integrated experimental campaign held in 2010 in GEKKO XII and LFEX facility in Institute of Laser Engineering Osaka (ILE), the Xylen based new liquid scintillator coupled with the gated photomultiplier tube has successfully recorded neutron signal with heating the energy of up to 400 J. However there was significant large background in the signal originated from neutrons via (γ,n) reaction from the target chamber wall. The neutron collimator was developed and implemented to suppress these neutron backgrounds. We succeeded to record a very clear neutron signals in every shot in the fast ignitor experimental campaign held in July 2012 with the heating laser energy of around 1000 J with the pulse width of 2.2 ps. The details of the detector and the result of the fast ignition experiment will be presented.

  19. CHRONICLE: International forum on advanced high-power lasers and applications (AHPLA '99)

    NASA Astrophysics Data System (ADS)

    Afanas'ev, Yurii V.; Zavestovskaya, I. N.; Zvorykin, V. D.; Ionin, Andrei A.; Senatsky, Yu V.; Starodub, Aleksandr N.

    2000-05-01

    A review of reports made on the International Forum on Advanced High-Power Lasers and Applications, which was held at the beginning of November 1999 in Osaka (Japan), is presented. Five conferences were held during the forum on High-Power Laser Ablation, High-Power Lasers in Energy Engineering, High-Power Lasers in Civil Engineering and Architecture, High-Power Lasers in Manufacturing, and Advanced High-Power Lasers. The following trends in the field of high-power lasers and their applications were presented: laser fusion, laser applications in space, laser-triggered lightning, laser ablation of materials by short and ultrashort pulses, application of high-power lasers in manufacturing, application of high-power lasers in mining, laser decommissioning and decontamination of nuclear reactors, high-power solid-state and gas lasers, x-ray and free-electron lasers. One can find complete information on the forum in SPIE, vols. 3885-3889.

  20. From the desk of the Editor-in-Chief

    NASA Astrophysics Data System (ADS)

    Hei, Tom K.

    2015-07-01

    Life Sciences in Space Research had a prominent presence at the International Congress of Radiation Research (ICRR) meeting held in Kyoto, Japan from May 25th-29th, with seven of the eleven editors attending the meeting. A journal booth was also put up at the pre-ICRR satellite meeting on Space Radiation and Heavy Ions in Therapy (SRHITS) held a few days earlier in Osaka. Since the inception of LSSR last year, the editors and publisher have promoted the journal at a number of major conferences including COSPAR 2014 in Moscow, the annual meeting of the Radiation Research Society and the NASA Space Radiation Investigators Meeting. These efforts have increased awareness of the journal among investigators in space life sciences and related fields. The number of monthly downloads of articles from the journal website averages 2000, a respectable number for a brand new journal.