Sample records for kairi klves marika
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NASA Technical Reports Server (NTRS)
Groleau, Nicolas; Frainier, Richard; Colombano, Silvano; Hazelton, Lyman; Szolovits, Peter
1993-01-01
This paper describes portions of a novel system called MARIKA (Model Analysis and Revision of Implicit Key Assumptions) to automatically revise a model of the normal human orientation system. The revision is based on analysis of discrepancies between experimental results and computer simulations. The discrepancies are calculated from qualitative analysis of quantitative simulations. The experimental and simulated time series are first discretized in time segments. Each segment is then approximated by linear combinations of simple shapes. The domain theory and knowledge are represented as a constraint network. Incompatibilities detected during constraint propagation within the network yield both parameter and structural model alterations. Interestingly, MARIKA diagnosed a data set from the Massachusetts Eye and Ear Infirmary Vestibular Laboratory as abnormal though the data was tagged as normal. Published results from other laboratories confirmed the finding. These encouraging results could lead to a useful clinical vestibular tool and to a scientific discovery system for space vestibular adaptation.
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An Analysis of the President’s Budgetary Proposals for Fiscal Year 2010
2009-06-01
Ozanne, Frank Russek, Marika Santoro, Kurt Seibert, Sven Sinclair, and David Weiner carried out the modeling . Barry Blom of CBO’s Projections Unit...Baseline Policy Assumptions 15 Ways in Which the President’s Proposals Would Affect the Economy 15 The Models and Their Results 21 The Potential Economic...Effects of Selected Proposals in the President’s 2010 Budget 27 The Models Used to Analyze the Supply-Side Macroeconomic Effects of the President’s
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Six calendar systems in the European history from 18^{th} to 20^{th} Century
NASA Astrophysics Data System (ADS)
Theodossiou, Efstratios; Manimanis, Vassilios N.; Dimitrijević, Milan S.
The following calendar systems, introduced in Europe from 18^{th} to 20^{th} century, which were in use for a shorter or longer period by a larger or smaller community, were reviewed and discussed: The French Revolutionary Calendar, the Theosebic calendar invented by Theophilos Kairis, the Revolutionary Calendar of the Soviet Union (or 'Bolshevik calendar'), the Fascist calendar in Italy and the calendar of the Metaxas dictatorship in Greece before World War II. Also the unique of them, which is still in use, the New Rectified Julian calendar of the Orthodox Church, adopted according to proposition of Milutin Milanković on the Congress of Orthodox Churches in 1923 in Constantinople, is presented and discussed. At the end, difficulties to introduce a new calendar are discussed as well.
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Transcription of a recombinant bunyavirus RNA template by transiently expressed bunyavirus proteins.
Dunn, E F; Pritlove, D C; Jin, H; Elliott, R M
1995-08-01
We describe a convenient system for analyzing bunyavirus transcription using a recombinant RNA template derived from the plasmid pBUNSCAT, which comprises a negative-sense reporter gene (chloramphenicol acetyltransferase or CAT) flanked by the exact 5' and 3' untranslated regions of the Bunyamwera virus (BUN) S RNA segment. When cells which expressed bunyavirus proteins (either by recombinant vaccinia viruses or by the vaccinia virus-T7 system) were transfected with BUNSCAT RNA, CAT activity could be measured, indicating transcription of the negative-sense reporter RNA into mRNA. The system permits investigation of both the protein and RNA sequence requirements for transcription. Extensions of 2 bases at the 5' end or 11 or 35 bases at the 3' end of BUNSCAT RNA allowed transcription but a lower level than the wild-type template. Deletion of the 5 nucleotides at the 3' end of BUNSCAT RNA reduced CAT activity by > 99%. Investigation of the viral protein requirements of the system showed that only the bunyavirus L and N proteins were needed for CAT activity. The BUN L protein was also able to transcribe the reporter RNA in concert with the N proteins of closely related bunyaviruses such as Batai, Cache Valley, Maguari, Main Drain, and Northway, but only inefficiently with those of Kairi, Guaroa, or Lumbo viruses. When BUN L proteins containing specific mutations were expressed CAT activity was only observed using those mutated L proteins previously reported to be active in a nucleocapsid transfection assay (H. Jin and R. M. Elliott, 1992, J. Gen. Virol. 73, 2235-2244). These results illustrate the utility of this system for a detailed genetic analysis of the factors involved in bunyavirus transcription.
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Sweet, Shane Norman; Rocchi, Meredith; Arbour-Nicitopoulos, Kelly; Kairy, Dahlia; Fillion, Brigitte
2017-10-19
assessment, participants will be randomly assigned to the intervention or control group. Participants in the intervention group will participate in 8 weekly, 1-hour video-based telerehabilitation sessions with a trained physical activity counselor, while participants in the control group will be asked to continue with their regular routine. We expect higher ratings of the basic psychological needs and autonomous motivation and lower scores for controlled motivation for the intervention group compared to the control group (Objective 1). We also expect that our video-based intervention will have moderate effects on exercise participation, as well as small-to-moderate positive effects on the quality of life‒related variables (Objective 2). Finally, we expect the intervention to have a small positive effect on psychosocial predictors of physical activity and well-being (Objective 3). We anticipate that the results will show that the intervention is appropriate for adults with paraplegia and feasible to test in a full-scale RCT. ClinicalTrials.gov NCT02833935; https://clinicaltrials.gov/ct2/show/NCT02833935 (Archived by WebCite at http://www.webcitation.org/6u8U9x2yt). ©Shane Norman Sweet, Meredith Rocchi, Kelly Arbour-Nicitopoulos, Dahlia Kairy, Brigitte Fillion. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 19.10.2017.
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Final Technical Report for Project "Improving the Simulation of Arctic Clouds in CCSM3"
DOE Office of Scientific and Technical Information (OSTI.GOV)
Stephen J. Vavrus
2008-11-15
greenhouse warming and the extent to which models adequately represent Arctic clouds in the modern climate. This site was used extensively in the IARC summer school projects. This work has also led to a collaboration this year during a 4-month visit I made to NCAR through its Faculty Fellowship Program. I worked with scientists Marika Holland, David Bailey, Andrew Gettleman, and Jen Kay, who are researching polar climate and/or clouds. I met with this group frequently during my visit, leading to some fruitful interactions. This work led to the discovery of a tightly coupled response of clouds and sea ice during intervals of rapid sea ice loss in greenhouse simulations, as well as advising on the evolving CCSM3.5 to CCSM4 model development. This involvement with NCAR also led to a longer-term connection, as I have recently begun a two-year stint on the SSC for CCSM.« less