Approaches to Cyber Intrusion Response. A Legal Foundations Study. Report 12 of 12

DTIC Science & Technology

1997-01-01

Computers: Controlling Behavior in Cyberspace through a Contract Law Paradigm, 35 Jurimetrics J. 1, 8-9 (1994). 5 Ingrid Becker, Cybercrime: Cops Can’t...Computers: Controlling Behavior in Cyberspace through a Contract Law Paradigm, 35 JURIMETRICS J. 1-15 (1994). 9 • Pro: This approach allows the victim

Oral challenges with four apple cultivars result in significant differences in oral allergy symptoms.

PubMed

Nybom, Hilde; Cervin-Hoberg, Charlotte; Andersson, Morgan

2013-01-01

We analyzed the hypoallergenic potential of a recently bred apple selection with unusually low content of Mal d 1, using an oral challenge model with three additional apple cultivars for comparison. Sixty-six birch pollen-allergic individuals with a history of oral allergy syndrome after apple intake were subjected to a double-blind oral provocation with two apple cultivars (B:0654 and 'Discovery'). Thirteen also tested two other apple cultivars ('Ingrid Marie' and 'Gloster'). Three doses were given consecutively, 30 min apart: 10 g without peel, and 10 and 50 g with peel. A final assessment was conducted 30 min after the last intake. Oral symptoms were graded from 0 to 5. Total oral symptom score (TOS) included all scores for each cultivar at all time points. B:0654 induced significantly higher TOS than 'Discovery' when tested by 66 individuals, in spite of its lower Mal d 1 content. TOS values were higher in females and increased with increasing age of the individuals when challenged with 'Discovery'. Among the 13 individuals who tested all four cultivars, B:0654 produced a higher score after the second dose compared to 'Ingrid Marie'. This was also the case after the third dose compared to 'Ingrid Marie' and 'Gloster', and again 30 min after the last intake compared to each of the other three cultivars, as well as a higher TOS compared to each of the other three cultivars (all p < 0.01). Our test was safe and well tolerated, and produced significant differences among the apple cultivars. Contrary to expectations, B:0654 was less well tolerated than the other three cultivars. Copyright © 2013 S. Karger AG, Basel.

Influence of Theobromine on Heat Production and Body Temperatures in Cold-Exposed Humans: A Preliminary Report

DTIC Science & Technology

1989-11-01

excellent assistance of Ms. Ingrid Schmegner. Ms. Jacquelyn Doucette and Mr. Robert Limmer . ,O2ma. and body fat determinations were performed by Mr...by an ephedrine/caffeine mixture in humans. J. Appl. Physiol. 67(l): 438-444, 1989. 2 -)- 17. Vallerand, A.L., R. Limmer and I.F. Schmegner. Computer

Learning Languages, 2000-2001.

ERIC Educational Resources Information Center

Rosenbusch, Marcia H., Ed.

2001-01-01

This journal serves the profession by providing a medium for the sharing of information, ideas, and concerns among teachers, administrators, researchers, and others interested in the early learning of languages. Articles in this volume include the following: "Foreign Language Teaching: What We Can Learn from Other Countries" (Ingrid U.…

"Speak Out. Act Up. Move Forward." Disobedience-Based Arts Education

ERIC Educational Resources Information Center

Kotin, Alison; Aguirre McGregor, Stella; Pellecchia, DeAnna; Schatz, Ingrid; Liu, Shaw Pong

2013-01-01

In this essay, Alison Kotin, Stella Aguirre McGregor, DeAnna Pellecchia, Ingrid Schatz, and Shaw Pong Liu reflect on their experiences working with public high school students to create "Speak Out. Act Up. Move Forward.," a performative response to current and historical acts of civil disobedience. The authors--a group of instructors…

Philanthropically Always Coca-Cola.

ERIC Educational Resources Information Center

Black Issues in Higher Education, 1997

1997-01-01

In an interview, the head of the Coca-Cola Foundation, Ingrid Saunders Jones, discusses the foundation's objectives for financial support of education and the role of targeted and ethnic marketing, programs at historically black colleges and universities, recent growth of the endowment, number of projects funded, and the role of the Coca-Cola…

First demonstration of an emulsion multi-stage shifter for accelerator neutrino experiments in J-PARC T60

NASA Astrophysics Data System (ADS)

Yamada, K.; Aoki, S.; Cao, S.; Chikuma, N.; Fukuda, T.; Fukuzawa, Y.; Gonin, M.; Hayashino, T.; Hayato, Y.; Hiramoto, A.; Hosomi, F.; Inoh, T.; Iori, S.; Ishiguro, K.; Kawahara, H.; Kim, H.; Kitagawa, N.; Koga, T.; Komatani, R.; Komatsu, M.; Matsushita, A.; Mikado, S.; Minamino, A.; Mizusawa, H.; Matsumoto, T.; Matsuo, T.; Morimoto, Y.; Morishima, K.; Morishita, M.; Naganawa, N.; Nakamura, K.; Nakamura, M.; Nakamura, Y.; Nakano, T.; Nakatsuka, Y.; Nakaya, T.; Nishio, A.; Ogawa, S.; Oshima, H.; Quilain, B.; Rokujo, H.; Sato, O.; Seiya, Y.; Shibuya, H.; Shiraishi, T.; Suzuki, Y.; Tada, S.; Takahashi, S.; Yokoyama, M.; Yoshimoto, M.

2017-06-01

We describe the first ever implementation of a clock-based, multi-stage emulsion shifter in an accelerator neutrino experiment. The system was installed in the neutrino monitoring building at the Japan Proton Accelerator Research Complex as part of a test experiment, T60, and stable operation was maintained for a total of 126.6 days. By applying time information to emulsion films, various results were obtained. Time resolutions of 5.3-14.7 s were evaluated in an operation spanning 46.9 days (yielding division numbers of 1.4-3.8×105). By using timing and spatial information, reconstruction of coincident events consisting of high-multiplicity and vertex-contained events, including neutrino events, was performed. Emulsion events were matched to events observed by INGRID, one of the on-axis near detectors of the T2K experiment, with high reliability (98.5%), and hybrid analysis of the emulsion and INGRID events was established by means of the multi-stage shifter. The results demonstrate that the multi-stage shifter can feasibly be used in neutrino experiments.

Optimization of Integrative Passive Sampling Approaches for Use in the Epibenthic Environment

DTIC Science & Technology

2016-12-23

Passive sampler, POCIS, Integrative, Sediment , Benthic 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT 18. NUMBER OF PAGES 19a...Unexploded ordnance, Passive sampler, POCIS, Integrative, Sediment , Benthic v Acknowledgements Dr. Shane Morrison and Ms. Ingrid...flow and turbulence near the sampler. In complex environments at the sediment – water interface, this may limit the utility of passive sampling

Effective Advocacy for the Gifted in Belgium

ERIC Educational Resources Information Center

Kumps, Luc

2008-01-01

In 2001, the author was still saying things like "Giftedness is a luxury problem," and "Why do parents let their children skip grades? School isn't a race! No need to arrive first at the finish!" He didn't realize that his wife Ingrid and him would soon be confronted with the "luxury problem." Their son Felix, then 3…

Fort Knox Trend Analysis, Encroachment Study, and Perimeter Expansion Opportunities in Support of Military Training

DTIC Science & Technology

2006-03-01

converters from GIL and many other formats. Other hilites: command line argument parsing, a simple set of routines for de- veloping Xwindows graphical...Ramakrishna Nemani, James E. Vogelmann, V. Ruth Hobson, Benjamin Tuttle, Jeff Safran, Ingrid Nelson. (2001). “Development Sprawl Impacts on the... Sale Prices as a Basis for Farm Land Appraisal,” Technical Bulletin, University of Minnesota. Hosmer, D.W., and S. Lemeshow. (1989). Applied

Neural Network Design on the SRC-6 Reconfigurable Computer

DTIC Science & Technology

2006-12-01

fingerprint identification. In this field, automatic identification methods are used to save time, especially for the purpose of fingerprint matching in...grid widths and lengths and therefore was useful in producing an accurate canvas with which to create sample training images. The added benefit of...tools available free of charge and readily accessible on the computer, it was simple to design bitmap data files visually on a canvas and then

Developing the Multimedia User Interface Component (MUSIC) for the Icarus Presentation System (IPS)

DTIC Science & Technology

1993-12-01

AD-A276 341 In-House Report December 1993 DEVELOPING THE MULTIMEDIA USER INTERFACE COMPONENT ( MUSIC ) FOR THE ICARUS PRESENTATION SYSTEM (IPS) Ingrid...DATEs COVERED 7 December 1993 Ina-House Jun - Aug 93 4 TWLE AM SL1sM1E & FUNDING NUMBERS DEVELOPING THE MULTIMEDIA USER INTERFACE COMPONENT ( MUSIC ) PE...the Multimedia User Interface Component ( MUSIC ). This report documents the initial research, design and implementation of a prototype of the MUSIC

Efficacy of Oritavancin in a Murine Model of Bacillus anthracis Spore Inhalation Anthrax

DTIC Science & Technology

2008-06-21

Bélanger, and Adel Rafai Far for characterizing oritavancin pharmacokinetics in mice. We acknowledge the support of Ingrid Sarmiento for assistance...antibiotics. FEMS Microbiol. Rev. 26:511–532. 2. Arhin, F. F., I. Sarmiento , A. Belley, G. A. McKay, D. C. Draghi, P. Grover, D. Sahm, T. R. Parr, Jr...Chemother. 52:1597–1603. 3. Arhin, F. F., I. Sarmiento , T. R. Parr, Jr., and G. Moeck. 2007. Mechanisms of action of oritavancin in Staphylococcus

Now & Then: Ingrid Proctor-Fridia: Quality Assurance Representative.

ERIC Educational Resources Information Center

Barnes, Sue; Michalowicz, Karen Dee

1995-01-01

Describes the use of geometry now by a U.S. Department of Defense quality assurance representative and in ancient times by the Egyptians and Babylonians. Includes reproducible student worksheets on quality assurance. (MKR)

Transcriptional Regulation of Mouse Ribosomal RNA Synthesis by Pathways Involving Protein Kinase C, Calcium, Insulin and Serum

DTIC Science & Technology

1992-05-08

Southern California 1ha.iITRINUTIONI AVAILASILITY STATEMENT 12b. DITIUINCCD1 This document has been approved { OSRUTO for public release and sale ...and 500 gIl of CHCI3 : Isoamyl alcohol (24 : 1), and 2X with 1ml of CHCI 3 : Iso amyl alcohol (24 : 1). RNA was precipitated at -200C overnight in the...control. Plasmid constructions. Plasmids pMrA and pMrD (Kuhn and Grummt, 1987) were kind gifts of Dr. Ingrid Grummt. Plasmid p119 and p123 (Arnhiem

ORAC-DR -- imaging data reduction

NASA Astrophysics Data System (ADS)

Currie, Malcolm J.; Cavanagh, Brad

ORAC-DR is a general-purpose automatic data-reduction pipeline environment. This document describes its use to reduce imaging data collected at the United Kingdom Infrared Telescope (UKIRT) with the UFTI, UIST, IRCAM, and Michelle instruments; at the Anglo-Australian Telescope (AAT) with the IRIS2 instrument; at the Very Large Telescope with ISAAC and NACO; from Magellan's Classic Cam, at Gemini with NIRI, and from the Isaac Newton Group using INGRID. It outlines the algorithms used and how to make minor modifications to them, and how to correct for errors made at the telescope.

ORAC-DR: Overview and General Introduction

NASA Astrophysics Data System (ADS)

Economou, Frossie; Jenness, Tim; Currie, Malcolm J.; Adamson, Andy; Allan, Alasdair; Cavanagh, Brad

ORAC-DR is a general purpose automatic data reduction pipeline environment. It currently supports data reduction for the United Kingdom Infrared Telescope (UKIRT) instruments UFTI, IRCAM, UIST and CGS4, for the James Clerk Maxwell Telescope (JCMT) instrument SCUBA, for the William Herschel Telescope (WHT) instrument INGRID, for the European Southern Observatory (ESO) instrument ISAAC and for the Anglo-Australian Telescope (AAT) instrument IRIS-2. This document describes the general pipeline environment. For specific information on how to reduce the data for a particular instrument, please consult the appropriate ORAC-DR instrument guide.

Stories of relative privilege: power and social change in feminist community psychology.

PubMed

Mulvey, A; Terenzio, M; Hill, J; Bond, M A; Huygens, I; Hamerton, H R; Cahill, S

2000-12-01

Stories about community work in New Zealand and Scotland are presented to describe and reflect on issues central to feminist community psychology. Organizing a lesbian festival, Ingrid Huygens describes feminist processes used to equalize resources across Maori (indigenous) and Pakeha (white) groups. Heather Hamerton presents her experiences as a researcher using collective memory work to reflect on adolescent experiences related to gender, ethnicity, and class. Sharon Cahill chronicles dilemmas and insights from focus groups about anger with women living in public housing in Scotland. Each story chronicles experiences related to oppression and privilege, and describes the author's emotions and reflections. Individually and collectively, the stories illustrate the potential offered by narrative methods and participatory processes for challenging inequalities and encouraging social justice.

75 FR 4579 - Certificate of Alternative Compliance for the Offshore Supply Vessel INGRID

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-28

... DEPARTMENT OF HOMELAND SECURITY Coast Guard [Docket No. USCG-2009-1078] Certificate of Alternative... Guard announces that a Certificate of Alternative Compliance was issued for the offshore [[Page 4580... Alternative Compliance was issued on December 7, 2009. ADDRESSES: The docket for this notice is available for...

Ingrid Rinner-Kuhn v. FWW. Spezial-Gebaudereinigung GmbH. and Co. [13 July 1989].

PubMed

1989-01-01

The plaintiff worked 10 hours a week for the defendant and, when she became ill, sought payment of her wages under the German sick pay law. After her employer refused to pay her, citing a provision of the German law that exempted employers from paying for sickness leave when a worker works fewer than 10 hours a week, she challenged the law as violating equal pay provisions of Article 119 of the European Communities Treaty. To support her challenge she pointed to statistics showing that a far greater percentage of workers working no more than 10 hours a week were women than men. Upon referral of the case by the German court hearing it, the European Court of Justice held that Article 119 precludes national legislation permitting employers to exclude from payment of sick pay employees who do not work more than 10 hours a week if that measure affects a far greater number of men than women, unless it is shown that the legislation is justified by objective facts unrelated to any discrimination based on sex. It also ruled that it was up to the German court to determine whether the legislation in question was so justified.

Chain conformational and physicochemical properties of fucoidans from sea cucumber.

PubMed

Xu, Xiaoqi; Xue, Changhu; Chang, Yaoguang; Wang, Jun; Jiang, Kunhao

2016-11-05

Although fucoidans from sea cucumber (SC-FUCs) have been proven as potential bioactive polysaccharides and functional food ingridents, their chain conformation and physicochemical properties were still poorly understood. This study investigated the chain conformation of fucoidans from sea cucumber Acaudina molpadioides (Am-FUC), Isostichopus badionotus (Ib-FUC) and Apostichopus japonicus (Aj-FUC), of which primary structure has been recently clarified. Chain conformation parameters demonstrated that studied SC-FUCs adopted random coil conformation in 150mM NaCl solution (pH 7.4). Based on the worm-like cylinder model and atomic force microscopy, the chain stiffness of SC-FUCs was further evaluated as Am-FUC≈Ib-FUC>Aj-FUC. It was suggested that the existence of branch structure increased the chain flexibility, while sulfated pattern exerted limited influence. SC-FUCs demonstrated shear-thinning rheological behavior and negative charge. Am-FUC possessed a higher thermostability than Ib-FUC and Aj-FUC. These results have important implications for understanding the molecular characteristics of SC-FUCs, which could facilitate their further application. Copyright © 2016 Elsevier Ltd. All rights reserved.

Mapping mass movement processes using terrestrial LIDAR: a swift mechanism for hazard and disaster risk assessment

NASA Astrophysics Data System (ADS)

Garnica-Peña, Ricardo; Murillo-García, Franny; Alcántara-Ayala, Irasema

2014-05-01

The impact of disasters associated with mass movement processes has increased in the past decades. Either triggered by earthquakes, volcanic activity or rainfall, mass movement processes have affected people, infrastructure, economic activities and the environment in different parts of the world. Extensive damage is particularly linked to rainfall induced landslides due to the occurrence of tropical storms, hurricanes, and the combination of different meteorological phenomenon on exposed vulnerable communities. Therefore, landslide susceptibility analysis, hazard and risk assessments are considered as significant mechanisms to lessen the impact of disasters. Ideally, these procedures ought to be carried out before disasters take place. However, under intense or persistent periods of rainfall, the evaluation of potentially unstable slopes becomes a critical issue. Such evaluations are constrained by the availability of resources, capabilities and scientific and technological tools. Among them, remote sensing has proved to be a valuable tool to evaluate areas affected by mass movement processes during the post-disaster stage. Nonetheless, the high cost of imagery acquisition inhibits their wide use. High resolution topography field surveys consequently, turn out to be an essential approach to address landslide evaluation needs. In this work, we present the evaluation and mapping of a series of mass movement processes induced by hurricane Ingrid in September, 2013, in Teziutlán, Puebla, México, a municipality situated 265 km Northeast of Mexico City. Geologically, Teziutlán is characterised by the presence, in the North, of siltstones and conglomerates of the Middle Jurassic, whereas the central and Southern sectors consist of volcanic deposits of various types: andesitic tuffs of Tertiary age, and basalts, rhyolitic tuffs and ignimbrites from the Quaternary. Major relief structures are formed by the accumulation of volcanic material; lava domes, partially buried

Hurricane Imaging Radiometer

NASA Technical Reports Server (NTRS)

Cecil, Daniel J.; Biswas, Sayak K.; James, Mark W.; Roberts, J. Brent; Jones, W. Linwood; Johnson, James; Farrar, Spencer; Sahawneh, Saleem; Ruf, Christopher S.; Morris, Mary;

The Coplane Analysis Technique for Three-Dimensional Wind Retrieval Using the HIWRAP Airborne Doppler Radar

NASA Technical Reports Server (NTRS)

Didlake, Anthony C., Jr.; Heymsfield, Gerald M.; Tian, Lin; Guimond, Stephen R.

2015-01-01

The coplane analysis technique for mapping the three-dimensional wind field of precipitating systems is applied to the NASA High Altitude Wind and Rain Airborne Profiler (HIWRAP). HIWRAP is a dual-frequency Doppler radar system with two downward pointing and conically scanning beams. The coplane technique interpolates radar measurements to a natural coordinate frame, directly solves for two wind components, and integrates the mass continuity equation to retrieve the unobserved third wind component. This technique is tested using a model simulation of a hurricane and compared to a global optimization retrieval. The coplane method produced lower errors for the cross-track and vertical wind components, while the global optimization method produced lower errors for the along-track wind component. Cross-track and vertical wind errors were dependent upon the accuracy of the estimated boundary condition winds near the surface and at nadir, which were derived by making certain assumptions about the vertical velocity field. The coplane technique was then applied successfully to HIWRAP observations of Hurricane Ingrid (2013). Unlike the global optimization method, the coplane analysis allows for a transparent connection between the radar observations and specific analysis results. With this ability, small-scale features can be analyzed more adequately and erroneous radar measurements can be identified more easily.

Understanding the potential benefits of thyme and its derived products for food industry and consumer health: From extraction of value-added compounds to the evaluation of bioaccessibility, bioavailability, anti-inflammatory, and antimicrobial activities.

PubMed

Lorenzo, Jose M; Mousavi Khaneghah, Amin; Gavahian, Mohsen; Marszałek, Krystian; Eş, Ismail; Munekata, Paulo E S; Ferreira, Isabel C F R; Barba, Francisco J

2018-05-17

Natural bioactive compounds isolated from several aromatic plants have been studied for centuries due to their unique characteristics that carry great importance in food, and pharmaceutical, and cosmetic industries. For instance, several beneficial activities have been attributed to some specific compounds found in Thymus such as anti-inflammatory, antioxidant, antimicrobial, and antiseptic properties. Moreover, these compounds are classified as Generally Recognized as Safe (GRAS) which means they can be used as an ingrident of may food producs. Conventional extraction processes of these compounds and their derived forms from thyme leaves are well established. Hoewever, they present some important drawbacks such as long extraction time, low yield, high solvent consumption and degradation thermolabile compounds. Therefore, innovative extraction techniques such as ultrasound, microwave, enzyme, ohmic and heat-assisted methods can be useful strategies to enhance the exytraction yield and to reduce processing temperature, extraction time, and energy and solvent consumption. Furthermore, bioaccessibility and bioavailability aspects of these bioactive compounds as well as their metabolic fates are crucial for developing novel functional foods. Additionally, immobilization methods to improve stability, solubility, and the overall bioavailability of these valuable compounds are necessary for their commercial applications. This review aims to give an overall perspective of innovative extraction techniques to extract the targeted compounds with anti-inflammatory and antimicrobial activities. Moreover, the bioaccessi-bility and bioavailability of these compounds before and after processing discussed. In addition, some of the most important characteristics of thyme and their derived products discussed in this paper.

Voltage-sensing phosphatase modulation by a C2 domain.

PubMed

Castle, Paul M; Zolman, Kevin D; Kohout, Susy C

2015-01-01

The voltage-sensing phosphatase (VSP) is the first example of an enzyme controlled by changes in membrane potential. VSP has four distinct regions: the transmembrane voltage-sensing domain (VSD), the inter-domain linker, the cytosolic catalytic domain, and the C2 domain. The VSD transmits the changes in membrane potential through the inter-domain linker activating the catalytic domain which then dephosphorylates phosphatidylinositol phosphate (PIP) lipids. The role of the C2, however, has not been established. In this study, we explore two possible roles for the C2: catalysis and membrane-binding. The Ci-VSP crystal structures show that the C2 residue Y522 lines the active site suggesting a contribution to catalysis. When we mutated Y522 to phenylalanine, we found a shift in the voltage dependence of activity. This suggests hydrogen bonding as a mechanism of action. Going one step further, when we deleted the entire C2 domain, we found voltage-dependent enzyme activity was no longer detectable. This result clearly indicates the entire C2 is necessary for catalysis as well as for modulating activity. As C2s are known membrane-binding domains, we tested whether the VSP C2 interacts with the membrane. We probed a cluster of four positively charged residues lining the top of the C2 and suggested by previous studies to interact with phosphatidylinositol 4,5-bisphosphate [PI(4,5)P2] (Kalli et al., 2014). Neutralizing those positive charges significantly shifted the voltage dependence of activity to higher voltages. We tested membrane binding by depleting PI(4,5)P2 from the membrane using the 5HT2C receptor and found that the VSD motions as measured by voltage clamp fluorometry (VCF) were not changed. These results suggest that if the C2 domain interacts with the membrane to influence VSP function it may not occur exclusively through PI(4,5)P2. Together, this data advances our understanding of the VSP C2 by demonstrating a necessary and critical role for the C2 domain in

Air ambulance and hospital services for critically ill and injured in Greenland, Iceland and the Faroe Islands: how can we improve?

PubMed Central

Gunnarsson, Björn; Jensen, Niels S Kieler; Garði, Tummas i; Harðardóttir, Helga; Stefánsdóttir, Lilja; Heimisdóttir, María

2015-01-01

The Nordic Atlantic Cooperation (NORA) is an intergovernmental organization under the auspices of the Nordic Council of Ministers. The NORA region comprises Greenland, Iceland, Faroe Islands and western coastal areas of Norway. Historical, cultural and institutional links bind these nations together in multiple ways, and regional co-operation has in recent years become a focus of interest. This commentary addresses air medical services (AMSs) and available advanced hospital services in the 3 smallest NORA countries challenged sparse populations, hereafter referred to as the region. It seems likely that strengthened regional co-operation can help these countries to address common challenges within health care by exchanging know-how and best practices, pooling resources and improving the efficiency of care delivery. The 4 largest hospitals in the region, Dronning Ingrids Hospital in Nuuk (Greenland), Landspítali in Reykjavík and Sjúkrahúsið á Akureyri, (both in Iceland) and Landssjúkrahúsið Tórshavn on the Faroe Islands, have therefore undertaken the project Network for patient transport in the North-West Atlantic (in Danish: Netværk for patienttransport i Vest-Norden). The goal of the project, and of this article, is to exchange information and provide an overview of current AMSs and access to acute hospital care for severely ill or injured patients in the 3 participating countries. Of equal importance is the intention to highlight the need for increased regional co-operation to optimize use of limited resources in the provision of health care services. PMID:26066019

GAS CLOUDS RAINING STAR STUFF ONTO MILKY WAY GALAXY

NASA Technical Reports Server (NTRS)

2002-01-01

This composite radio light image and rendition of our galaxy as seen in visible light shows enigmatic 'high-velocity clouds' of gas high above the plane of the Milky Way which rain gas into the galaxy, seeding it with the stuff of stars. The cloud outlined, and possibly others too, is now known to have low heavy element content and to be raining down onto the Milky Way disk, seeding it with material for star birth. Identifying this infalling gas helps in solving a long-standing mystery of galactic evolution by revealing a source of the low-metallicity gas required to explain the observed chemical composition of stars near the Sun. In this all-sky projection, the edge-on plane of our galaxy appears as a white horizontal strip. The false-color orange-yellow 'clouds' are regions containing neutral hydrogen, which glows in 21-centimeter radiation. Hubble Space Telescope's spectrograph was aimed at one of the clouds (encircled) to measure its detailed composition and velocity. This discovery is based on a combination of data from NASA's Hubble Space Telescope, three radio telescopes (at Effelsberg in Germany, and Dwingeloo and Westerbork in the Netherlands), the William Herschel Telescope on the island of La Palma and the Wisconsin H-alpha Mapper at NOAO's Kitt Peak Observatory. Photo Credits: Image composite by Ingrid Kallick of Possible Designs, Madison Wisconsin. The background Milky Way image is a drawing made at Lund Observatory. High-velocity clouds are from the survey done at Dwingeloo Observatory (Hulsbosch and Wakker, 1988).

Numerical simulation of groundwater flow in strongly anisotropic aquifers using multiple-point flux approximation method

NASA Astrophysics Data System (ADS)

Lin, S. T.; Liou, T. S.

2017-12-01

Numerical simulation of groundwater flow in anisotropic aquifers usually suffers from the lack of accuracy of calculating groundwater flux across grid blocks. Conventional two-point flux approximation (TPFA) can only obtain the flux normal to the grid interface but completely neglects the one parallel to it. Furthermore, the hydraulic gradient in a grid block estimated from TPFA can only poorly represent the hydraulic condition near the intersection of grid blocks. These disadvantages are further exacerbated when the principal axes of hydraulic conductivity, global coordinate system, and grid boundary are not parallel to one another. In order to refine the estimation the in-grid hydraulic gradient, several multiple-point flux approximation (MPFA) methods have been developed for two-dimensional groundwater flow simulations. For example, the MPFA-O method uses the hydraulic head at the junction node as an auxiliary variable which is then eliminated using the head and flux continuity conditions. In this study, a three-dimensional MPFA method will be developed for numerical simulation of groundwater flow in three-dimensional and strongly anisotropic aquifers. This new MPFA method first discretizes the simulation domain into hexahedrons. Each hexahedron is further decomposed into a certain number of tetrahedrons. The 2D MPFA-O method is then extended to these tetrahedrons, using the unknown head at the intersection of hexahedrons as an auxiliary variable along with the head and flux continuity conditions to solve for the head at the center of each hexahedron. Numerical simulations using this new MPFA method have been successfully compared with those obtained from a modified version of TOUGH2.

Voltage-sensing phosphatase modulation by a C2 domain

PubMed Central

Castle, Paul M.; Zolman, Kevin D.; Kohout, Susy C.

2015-01-01

The voltage-sensing phosphatase (VSP) is the first example of an enzyme controlled by changes in membrane potential. VSP has four distinct regions: the transmembrane voltage-sensing domain (VSD), the inter-domain linker, the cytosolic catalytic domain, and the C2 domain. The VSD transmits the changes in membrane potential through the inter-domain linker activating the catalytic domain which then dephosphorylates phosphatidylinositol phosphate (PIP) lipids. The role of the C2, however, has not been established. In this study, we explore two possible roles for the C2: catalysis and membrane-binding. The Ci-VSP crystal structures show that the C2 residue Y522 lines the active site suggesting a contribution to catalysis. When we mutated Y522 to phenylalanine, we found a shift in the voltage dependence of activity. This suggests hydrogen bonding as a mechanism of action. Going one step further, when we deleted the entire C2 domain, we found voltage-dependent enzyme activity was no longer detectable. This result clearly indicates the entire C2 is necessary for catalysis as well as for modulating activity. As C2s are known membrane-binding domains, we tested whether the VSP C2 interacts with the membrane. We probed a cluster of four positively charged residues lining the top of the C2 and suggested by previous studies to interact with phosphatidylinositol 4,5-bisphosphate [PI(4,5)P2] (Kalli et al., 2014). Neutralizing those positive charges significantly shifted the voltage dependence of activity to higher voltages. We tested membrane binding by depleting PI(4,5)P2 from the membrane using the 5HT2C receptor and found that the VSD motions as measured by voltage clamp fluorometry (VCF) were not changed. These results suggest that if the C2 domain interacts with the membrane to influence VSP function it may not occur exclusively through PI(4,5)P2. Together, this data advances our understanding of the VSP C2 by demonstrating a necessary and critical role for the C2 domain in

The IRI/LDEO Climate Data Library: Helping People use Climate Data

NASA Astrophysics Data System (ADS)

Blumenthal, M. B.; Grover-Kopec, E.; Bell, M.; del Corral, J.

2005-12-01

The IRI Climate Data Library (http://iridl.ldeo.columbia.edu/) is a library of datasets. By library we mean a collection of things, collected from both near and far, designed to make them more accessible for the library's users. Our datasets come from many different sources, many different "data cultures", many different formats. By dataset we mean a collection of data organized as multidimensional dependent variables, independent variables, and sub-datasets, along with the metadata (particularly use-metadata) that makes it possible to interpret the data in a meaningful manner. Ingrid, which provides the infrastructure for the Data Library, is an environment that lets one work with datasets: read, write, request, serve, view, select, calculate, transform, ... . It hides an extraordinary amount of technical detail from the user, letting the user think in terms of manipulations to datasets rather that manipulations of files of numbers. Among other things, this hidden technical detail could be accessing data on servers in other places, doing only the small needed portion of an enormous calculation, or translating to and from a variety of formats and between "data cultures". These operations are presented as a collection of virtual directories and documents on a web server, so that an ordinary web client can instantiate a calculation simply by requesting the resulting document or image. Building on this infrastructure, we (and others) have created collections of dynamically-updated images to faciliate monitoring aspects of the climate system, as well as linking these images to the underlying data. We have also created specialized interfaces to address the particular needs of user groups that IRI needs to support.

Division E Commission 49: Interplanetary Plasma and Heliosphere

NASA Astrophysics Data System (ADS)

Mann, Ingrid; Manoharan, P. K.; Gopalswamy, Natchimuthuk; Briand, Carine; Chashei, Igor V.; Gibson, Sarah E.; Lario, David; Hanaoka, Yoichiro; Malandraki, Olga; Kontar, Eduard; Richardson, John D.

2016-04-01

After a little more than forty years of work related to the interplanetary plasma and the heliosphere the IAU's Commission 49 was formally discontinued in 2015. The commission started its work when the first spacecraft were launched to measure the solar wind in-situ away from Earth orbit, both inward and outward from 1 AU. It now hands over its activities to a new commission during an era of space research when Voyager 1 measures in-situ the parameters of the local interstellar medium at the edge of the heliosphere. The commission will be succeeded by C.E3 with a similar area of responsibility but with more focused specific tasks that the community intends to address during the coming several years. This report includes a short description of the motivation for this commission and of the historical context. It then describes work from 2012 to 2015 during the present solar cycle 24 that has been the weakest in the space era so far. It gave rise to a large number of studies on solar energetic particles and cosmic rays. Other studies addressed e.g. the variation of the solar wind structure and energetic particle fluxes on long time scales, the detection of dust in the solar wind and the Voyager measurements at the edge of the heliosphere. The research is based on measurements from spacecraft that are at present operational and motivated by the upcoming Solar Probe + and Solar Orbiter missions to explore the vicinity of the Sun. We also report here the progress on new and planned radio instruments and their importance for heliospheric studies. Contributors to this report are Carine Briand, Yoichiro Hanaoka, Eduard Kontar, David Lario, Ingrid Mann, John D. Richardson.

Consent Processes for Mobile App Mediated Research: Systematic Review.

PubMed

Moore, Sarah; Tassé, Anne-Marie; Thorogood, Adrian; Winship, Ingrid; Zawati, Ma'n; Doerr, Megan

2017-08-30

Since the launch of ResearchKit on the iOS platform in March 2015 and ResearchStack on the Android platform in June 2016, many academic and commercial institutions around the world have adapted these frameworks to develop mobile app-based research studies. These studies cover a wide variety of subject areas including melanoma, cardiomyopathy, and autism. Additionally, these app-based studies target a variety of participant populations, including children and pregnant women. The aim of this review was to document the variety of self-administered remote informed consent processes used in app-based research studies available between May and September 2016. Remote consent is defined as any consenting process with zero in-person steps, when a participant is able to join a study without ever seeing a member of the research team. This type of review has not been previously conducted. The research community would benefit from a rigorous interrogation of the types of consent taken as part of the seismic shift to entirely mobile meditated research studies. This review examines both the process of information giving and specific content shared, with special attention to data privacy, aggregation, and sharing. Consistency across some elements of the app-based consent processes was found; for example, informing participants about how data will be curated from the phone. Variations in other elements were identified; for example, where specific information is shared and the level of detail disclosed. Additionally, several novel elements present in eConsent not typically seen in traditional consent for research were highlighted. This review advocates the importance of participant informedness in a novel and largely unregulated research setting. ©Sarah Moore, Anne-Marie Tassé, Adrian Thorogood, Ingrid Winship, Ma'n Zawati, Megan Doerr. Originally published in JMIR Mhealth and Uhealth (http://mhealth.jmir.org), 30.08.2017.

Increasing Reasoning Awareness: Video Analysis of Students' Two-Party Virtual Patient Interactions.

PubMed

Edelbring, Samuel; Parodis, Ioannis; Lundberg, Ingrid E

2018-02-27

Collaborative reasoning occurs in clinical practice but is rarely developed during education. The computerized virtual patient (VP) cases allow for a stepwise exploration of cases and thus stimulate active learning. Peer settings during VP sessions are believed to have benefits in terms of reasoning but have received scant attention in the literature. The objective of this study was to thoroughly investigate interactions during medical students' clinical reasoning in two-party VP settings. An in-depth exploration of students' interactions in dyad settings of VP sessions was performed. For this purpose, two prerecorded VP sessions lasting 1 hour each were observed, transcribed in full, and analyzed. The transcriptions were analyzed using thematic analysis, and short clips from the videos were selected for subsequent analysis in relation to clinical reasoning and clinical aspects. Four categories of interactions were identified: (1) task-related dialogue, in which students negotiated a shared understanding of the task and strategies for information gathering; (2) case-related insights and perspectives were gained, and the students consolidated and applied preexisting biomedical knowledge into a clinical setting; (3) clinical reasoning interactions were made explicit. In these, hypotheses were followed up and clinical examples were used. The researchers observed interactions not only between students and the VP but also (4) interactions with other resources, such as textbooks. The interactions are discussed in relation to theories of clinical reasoning and peer learning. The dyad VP setting is conducive to activities that promote analytic clinical reasoning. In this setting, components such as peer interaction, access to different resources, and reduced time constraints provided a productive situation in which the students pursued different lines of reasoning. ©Samuel Edelbring, Ioannis Parodis, Ingrid E Lundberg. Originally published in JMIR Medical Education (http

Computational fluid dynamics analysis of space shuttle main propulsion feed line 17-inch disconnect valves

NASA Technical Reports Server (NTRS)

Kandula, Max; Pearce, Daniel

1989-01-01

A steady incompressible three-dimensional (3-D) viscous flow analysis was conducted for the Space Shuttle Main Propulsion External Tank (ET)/Orbiter (ORB) propellant feed line quick separable 17-inch disconnect flapper valves for liquid oxygen (LO2) and liquid hydrogen (LH2). The main objectives of the analysis were to predict and correlate the hydrodynamic stability of the flappers and pressure drop with available water test data. Computational Fluid Dynamics (CFD) computer codes were procured at no cost from the public domain, and were modified and extended to carry out the disconnect flow analysis. The grid generator codes SVTGD3D and INGRID were obtained. NASA Ames Research Center supplied the flow solution code INS3D, and the color graphics code PLOT3D. A driver routine was developed to automate the grid generation process. Components such as pipes, elbows, and flappers can be generated with simple commands, and flapper angles can be varied easily. The flow solver INS3D code was modified to treat interior flappers, and other interfacing routines were developed, which include a turbulence model, a force/moment routine, a time-step routine, and initial and boundary conditions. In particular, an under-relaxation scheme was implemented to enhance the solution stability. Major physical assumptions and simplifications made in the analysis include the neglect of linkages, slightly reduced flapper diameter, and smooth solid surfaces. A grid size of 54 x 21 x 25 was employed for both the LO2 and LH2 units. Mixing length theory applied to turbulent shear flow in pipes formed the basis for the simple turbulence model. Results of the analysis are presented for LO2 and LH2 disconnects.

Rapid change in the ciprofloxacin resistance pattern among Neisseria gonorrhoeae strains in Nuuk, Greenland: time to reconsider preventive and treatment strategies.

PubMed

Rolskov, Anne Skjerbæk; Bjorn-Mortensen, Karen; Mulvad, Gert; Poulsen, Peter; Jensen, Jørgen Skov; Pedersen, Michael Lynge

2015-01-01

Sexually transmitted infections (STIs), including infections with Neisseria gonorrhoeae (GC), are highly incident in Greenland. Since January 2011, GC testing has been performed on urine with nucleic acid amplification tests (NAATs) by strand displacement amplification (Becton Dickinson ProbeTec). Monitoring of GC antibiotic susceptibility by culture was introduced in Nuuk in 2012. Until 2014, no cases of ciprofloxacin-resistant GC strains were reported. In this paper, we report the finding of ciprofloxacin-resistant GC and describe the most recent incidence of GC infections in Greenland. The number of urine NAATs and culture-positive swabs from January to October 2014 were obtained from the Central Laboratory at Queens Ingrid's Hospital in Nuuk and stratified on gender, place and period of testing. Incidence rates were estimated as number of urine NAAT * (12/10) per 100,000 inhabitants. Men in Nuuk with a positive NAAT for GC were encouraged to provide a urethral swab for culture and susceptibility testing. From January to October 2014, a total of 5,436 urine GC NAATs were performed on patients from Nuuk and 9,031 from the rest of Greenland. Of these, 422 (8%) and 820 (9%) were positive, respectively. From January to August, 6 (15%) cultures from Nuuk were ciprofloxacin resistant while in September and October, 26 (59%) were ciprofloxacin resistant (p<0.01). In total, 35 (40%) of 88 culture-positive isolates showed ciprofloxacin resistance. GC incidence in Nuuk was 3,017 per 100,000 inhabitants per year, compared to 2,491 per 100,000 inhabitants per year in the rest of Greenland. Within a short period, a rapid and dramatic change in ciprofloxacin susceptibility among GC strains isolated in Nuuk was documented and recommendation for first line treatments has changed. Continued monitoring and rethinking of primary and secondary preventive initiatives is highly recommended in this high GC incidence setting.

NEWS: Post-16 update

NASA Astrophysics Data System (ADS)

Campbell, Peter

2000-07-01

education must work together for common goals. In the coming year I hope that the Institute of Physics itself will organize discussion meetings among participants representing a full cross section of interests. The Institute of course already works closely with other associations speaking for science and for science education; inasmuch as they explore issues affecting science education broadly, the booklets may present new opportunities for cooperation. Last but not least, it is important that we influence government bodies regulating and funding education. Copies of the booklets can be downloaded as PDF files from the Web at post16.iop.org/shaping/ or purchased (at £5.50 per title, or £22 for all five titles, including p&p) from Ingrid Ebeyer at the Institute (ingrid.ebeyer@iop.org).

Public preferences for establishing nephrology facilities in Greenland: estimating willingness-to-pay using a discrete choice experiment.

PubMed

Kjær, Trine; Bech, Mickael; Kronborg, Christian; Mørkbak, Morten Raun

2013-10-01

At present there are no nephrology facilities in Greenland. Greenlandic patients with renal failure needing dialysis thus have to travel to Denmark to obtain treatment. For patients in haemodialysis this necessitates a permanent residence in Denmark. Our study was aimed at examining Greenlanders' preferences for establishing nephrology facilities in Greenland at Queen Ingrid's Hospital in Nuuk, and to estimate the associated change in welfare. Preferences were elicited using a discrete choice experiment (DCE). A random sample of 500 individuals of the general population was sent a postal questionnaire in which they were asked to consider the trade-offs of establishing nephrology facilities in Greenland as opposed to the current situation. This involved trading off the benefits of having such facilities in their home country against the costs of the intervention. Besides including a payment attribute described in terms of incremental tax payment, the DCE included two interventions attributes related to (1) the organisation of labour, and (2) the physical settings of the patients. Respondents succeeded in answering the DCE despite cultural and linguistic disparity. We found that all the included attributes had a significant effect on respondents' choices, and that respondents' answers to the DCE were in keeping with their values as stated in the questionnaire. DCE data was analyzed using a random parameter logit model reparametrized in willingness-to-pay space. The results showed that establishing facilities in Greenland were preferred to the current treatment in Denmark. The welfare estimate from the DCE, at DKK 18.74 million, exceeds the estimated annual costs of establishing treatment facilities for patients with chronic renal failure. Given the estimated confidence interval this result seems robust. Establishing facilities in Greenland therefore would appear to be welfare-improving, deriving positive net benefits. Despite the relatively narrow policy focus, we

Iodinated Contrast Media and the Alleged "Iodine Allergy": An Inexact Diagnosis Leading to Inferior Radiologic Management and Adverse Drug Reactions.

PubMed

Böhm, Ingrid; Nairz, Knud; Morelli, John N; Keller, Patricia Silva Hasembank; Heverhagen, Johannes T

2017-04-01

unenhanced scans and sometimes unnecessary prophylactic actions.. · The term "iodine allergy" should be omitted, because it is potentially dangerous and can decrease the quality of radiology exams.. Citation Format · Böhm Ingrid, Nairz Knud, Morelli John N et al. Iodinated Contrast Media and the Alleged "Iodine Allergy": An Inexact Diagnosis Leading to Inferior Radiologic Management and Adverse Drug Reactions. Fortschr Röntgenstr 2017; 189: 326 - 332. © Georg Thieme Verlag KG Stuttgart · New York.

The Effect of Integration of Self-Management Web Platforms on Health Status in Chronic Obstructive Pulmonary Disease Management in Primary Care (e-Vita Study): Interrupted Time Series Design.

PubMed

Talboom-Kamp, Esther Pwa; Verdijk, Noortje A; Kasteleyn, Marise J; Harmans, Lara M; Talboom, Irvin Jsh; Looijmans-van den Akker, Ingrid; van Geloven, Nan; Numans, Mattijs E; Chavannes, Niels H

2017-08-16

programs had no beneficial impact on the health status of COPD patients. Also, no differences were found between the patient groups receiving different levels of personal assistance. Netherlands Trial Registry NTR4098; http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=4098 (Archived by WebCite at http://www.webcitation.org/6sbM5PayG). ©Esther PWA Talboom-Kamp, Noortje A Verdijk, Marise J Kasteleyn, Lara M Harmans, Irvin JSH Talboom, Ingrid Looijmans-van den Akker, Nan van Geloven, Mattijs E Numans, Niels H Chavannes. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 16.08.2017.

Internet-Based Assessment of Oncology Health Care Professional Learning Style and Optimization of Materials for Web-Based Learning: Controlled Trial With Concealed Allocation.

PubMed

Micheel, Christine M; Anderson, Ingrid A; Lee, Patricia; Chen, Sheau-Chiann; Justiss, Katy; Giuse, Nunzia B; Ye, Fei; Kusnoor, Sheila V; Levy, Mia A

2017-07-25

or 4.0% more improvement on average; P=.004) and a higher follow-up test score than the control group (0.3 points or 3.3% more improvement on average; P=.02). Although the study demonstrated more learning with learning style-tailored educational materials, the magnitude of increased learning and the largely multimodal learning styles preferred by the study participants lead us to conclude that future content-creation efforts should focus on multimodal educational materials rather than learning style-tailored content. ©Christine M Micheel, Ingrid A Anderson, Patricia Lee, Sheau-Chiann Chen, Katy Justiss, Nunzia B Giuse, Fei Ye, Sheila V Kusnoor, Mia A Levy. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 25.07.2017.

Effects of solar dimming and brightening on the terrestrial carbon sink

NASA Astrophysics Data System (ADS)

Mercado, L.; Bellouin, N.; Sitch, S.; Boucher, O.; Huntingford, C.; Wild, M.; Cox, P. M.

2009-04-01

photosynthesis for climate model applications. Tellus Series B-Chemical and Physical Meteorology, 59, 553-565. Niyogi D., Chang H.I., Saxena V.K., Holt T., Alapaty K., Booker F., Chen F., Davis K.J., Holben B., Matsui T., Meyers T., Oechel W.C., Pielke R.A., Wells R., Wilson K. & Xue Y.K. (2004) Direct observations of the effects of aerosol loading on net ecosystem CO2 exchanges over different landscapes. Geophysical Research Letters, 31. Oliveira P.H.F., Artaxo P., Pires C., De Lucca S., Procopio A., Holben B., Schafer J., Cardoso L.F., Wofsy S.C. & Rocha H.R. (2007) The effects of biomass burning aerosols and clouds on the CO2 flux in Amazonia. Tellus Series B-Chemical and Physical Meteorology, 59, 338-349. Roderick M.L., Farquhar G.D., Berry S.L. & Noble I.R. (2001) On the direct effect of clouds and atmospheric particles on the productivity and structure of vegetation. Oecologia, 129, 21-30. Stanhill G. & Cohen S. (2001) Global dimming: a review of the evidence for a widespread and significant reduction in global radiation with discussion of its probable causes and possible agricultural consequences. 107, 255-278. Wild M., Gilgen H., Roesch A., Ohmura A., Long C.N., Dutton E.G., Forgan B., Kallis A., Russak V. & Tsvetkov A. (2005) From dimming to brightening: Decadal changes in solar radiation at Earth's surface. Science, 308, 847-850.

Implementation of the Enhanced Moderated Online Social Therapy (MOST+) Model Within a National Youth E-Mental Health Service (eheadspace): Protocol for a Single Group Pilot Study for Help-Seeking Young People.

PubMed

Rice, Simon; Gleeson, John; Leicester, Steven; Bendall, Sarah; D'Alfonso, Simon; Gilbertson, Tamsyn; Killackey, Eoin; Parker, Alexandra; Lederman, Reeva; Wadley, Greg; Santesteban-Echarri, Olga; Pryor, Ingrid; Mawren, Daveena; Ratheesh, Aswin; Alvarez-Jimenez, Mario

2018-02-22

using MOST+. Recruitment for the study commenced in October 2017. We expect to have initial results in March 2018, with more detailed qualitative and quantitative analyses to follow. This is the first Australia-wide research trial to pilot an online social media platform merging real-time clinical support, expert and peer moderation, interactive online therapy, and peer-to-peer social networking. The importance of the project stems from the need to develop innovative new models for the efficient delivery of responsive evidence-based online support to help-seeking young people. If successful, this research stands to complement and enhance e-mental health services in Australia. ©Simon Rice, John Gleeson, Steven Leicester, Sarah Bendall, Simon D'Alfonso, Tamsyn Gilbertson, Eoin Killackey, Alexandra Parker, Reeva Lederman, Greg Wadley, Olga Santesteban-Echarri, Ingrid Pryor, Daveena Mawren, Aswin Ratheesh, Mario Alvarez-Jimenez. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 22.02.2018.

NEWS: Post-16 update

NASA Astrophysics Data System (ADS)

1999-05-01

(post16) Making physics connect Doesn't Melvyn Bragg do a wonderful job, engaging both scientists and artists in sensitive discussion on Radio 4 about their methods and their purposes? But every week teachers have the chance to show their students that physics is a way of seeing the world that is well-connected with other aspects of knowledge and culture. The stakes are high: students who fail to appreciate this generally choose not to study the subject beyond GCSE. Most students find our preoccupation with technical detail off-putting. Accepting that we have a syllabus to cover, it's still a question of balance. In our teaching we should aim for variety in order to find ways to connect with every student's interests. Also, we can show that we (the nearest embodiment of a physicist some students will experience) are multidimensional and so fully human. Most important, teachers need flexibility to both encourage and respond to student comment and questions. The first booklet in the discussion series Shaping the Future takes up these themes. Rich in ideas for both immediate use and the longer term, it aims to stimulate debate and improve teaching. Copies cost £5.50 including postage and are available from Ingrid Ebeyer, Post-16 Initiative, Institute of Physics, 76 Portland Place, London W1N 3DH. How far is it? This question is asked in many family cars and school minibuses at the start of a journey, and answered by most in terms of hours and minutes rather than miles. What a good idea for introducing a social and historical perspective to a lesson on distance, velocity and time. How far can you actually get in a day? What is the range of human activity? Walking for eight hours will get many people about 25 miles. A pack horse will progress at much the same rate, but fast riding or a coach and team of horses will get further. Motorway driving (when the cones are on holiday) would take you nearly 500 miles. The 05.15 am train from Penzance arrives in Inverness at 7

Hazard analysis in active landslide areas in the State of Veracruz, Mexico

NASA Astrophysics Data System (ADS)

Wilde, Martina; Morales Barrera, Wendy V.; Rodriguez Elizarrarás, Sergio R.; Solleiro Rebolledo, Elizabeth; Sedov, Sergey; Terhorst, Birgit

2016-04-01

The year 2013 was characterized by strong storms and hurricanes like the Hurricanes Barbara and Ingrid and the tropical storms Barry and Fernand, which occurred between June and November affecting especially the coastal regions of Mexico. First of all, the State of Veracruz experienced a series of intense rainfalls and as consequences of these events over 780 landslides were registered. More than 45000 people suffered from evacuations. Located on the coast of the Gulf of Mexico, Veracruz has a wide range of altitude differences. The area with the highest elevations reaches from 5675 m.a.s.l. (Pico de Orizaba, the highest mountain of Mexico) to approximately 3000 m.a.s.l. and is characterized by steep slopes and V-shaped valleys. The mountains are part of the Sierra Madre Oriental and the Trans-Mexican Volcanic Belt. Plateaus and rounded hills are typical for the intermediate zones (3000 - 500 m.a.s.l.). The lowest zone (from 500 m.a.s.l. to sea level) is defined by moderate slopes, large rivers and coastal plain areas. The geology shows a variety and complexity of sedimentary and volcanic rocks. The sedimentary formations comprise claystones, siltstones, sandstones and calcareous rocks. Plateaus of basalts and andesites and deposits of ignimbrites are representative for this area. Even though Veracruz is a region highly endangered by landslides, currently there are no susceptibility maps or any other relevant information with high spatial resolution. Because of the lack of high definite information about the landslide hazards in this area, detailed investigations about the conditions (geology, geomorphology, thresholds, etc.) are indispensable. A doctoral grant from the German Academic Exchange Service (DAAD) allowed to carry out investigations in areas affected by large landslides in the year 2013. The selected study sites comprise damaged infrastructures and settlements. With a multi-methodological and interdisciplinary approach different processes and types of

Effects on Engagement and Health Literacy Outcomes of Web-Based Materials Promoting Physical Activity in People With Diabetes: An International Randomized Trial.

PubMed

Muller, Ingrid; Rowsell, Alison; Stuart, Beth; Hayter, Victoria; Little, Paul; Ganahl, Kristin; Müller, Gabriele; Doyle, Gerardine; Chang, Peter; Lyles, Courtney R; Nutbeam, Don; Yardley, Lucy

2017-01-23

the plain-text intervention group looked at significantly more sections of the intervention (mean difference -0.47, 95% CI -0.64 to -0.30, P<.001), but this did not lead to better outcomes. Health literacy outcomes, including attitudes and intentions to engage in physical activity, significantly improved following the intervention for participants in both intervention groups. These improvements were similar across higher and lower health literacy levels and in all countries. Participants in the interactive intervention group had acquired more diabetes knowledge (mean difference 0.80, 95% CI 0.65-0.94, P<.001). Participants from both groups reported high levels of website satisfaction and would recommend the website to others. Following established practice for simple, clear design and presentation and using a person-based approach to intervention development, with in-depth iterative feedback from users, may be more important than interactivity and audiovisual presentations when developing accessible digital health interventions to improve health literacy outcomes. International Standard Randomized Controlled Trial Number (ISRCTN): 43587048; http://www.isrctn.com/ISRCTN43587048. (Archived by WebCite at http://www.webcitation.org/6nGhaP9bv). ©Ingrid Muller, Alison Rowsell, Beth Stuart, Victoria Hayter, Paul Little, Kristin Ganahl, Gabriele Müller, Gerardine Doyle, Peter Chang, Courtney R Lyles, Don Nutbeam, Lucy Yardley. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 23.01.2017.

IN MY OPINION: Physics in the wider context

NASA Astrophysics Data System (ADS)

Morris, Andrew

1999-11-01

and progression opportunities for science specialists, whilst ensuring that the general public are scientifically literate. I think physics education has a serious contribution to make to all sections of society:The specialist, preparing for and progressing in a scientific/technological career. The skilled worker, analysing, understanding and innovating in any occupation. The citizen coping with increasing complexity in society. The individual trying to understanding the world into which they were born. To continue improving our educational systems and to assist each of these groups demands a grand alliance of people involved in physics education. Reflecting first on the wider context can help us choose appropriate points at which to intervene. Otherwise, educational improvement may be hampered, with valuable effort expended on positive reform actions rendered useless by constraints elsewhere in the system. How has the subject and its place in the curriculum evolved? What can be learned from previous curriculum innovations? What do public perceptions of physics tell us? The aim of the fifth Shaping the Future booklet is to encourage debate about where reform efforts should best be directed. Contributors will include Steve Adams, Michael Barnett, Sheila Carlton, John Berkeley, Martin Hollins, Marilyn Holyoake, Andrew Hunt, Roland Jackson, Jon Ogborn, Russell Stannard and Charles Thomas. A Discussion Meeting based on Physics in a wider context, at the ASE Annual Meeting, Leeds, promises to be lively. I hope you will come and express your views! If you would like to attend the meeting, to be held on 7 January 2000, and be sent a free copy of the manuscript for the 48 page booklet in advance, please contact: Ingrid Ebeyer, Post-16 Initiative, Institute of Physics, 76 Portland Place, London W1N 3DH (e-mail: 16-19project@iop.org)

Adherence to Web-Based Self-Assessments in Long-Term Direct-to-Patient Research: Two-Year Study of Multiple Sclerosis Patients.

PubMed

Jongen, Peter Joseph; Kremer, Ingrid E H; Hristodorova, Elena; Evers, Silvia M A A; Kool, Anton; van Noort, Esther M; Hiligsmann, Mickaël

2017-07-21

completion adherent for the MSQoL-54 and MA questionnaires, respectively. Whereas 85.5% (142/166) of the patients were interval adherent for the MSIP and MSQoL-54, 25.5% (41/161) were interval adherent for the MA questionnaire, with 73.9% (119/161) exceeding the maximum MA monthly interassessment interval. Completion adherence for the monthly short MA questionnaire was higher in patients with moderately high disability (EDSS 5.0-5.5) than for those with no or minimal disability (EDSS 0-2.5) (OR 5.47, 95% CI 1.08-27.69; P=.040). Completion adherence was also higher in patients with EDSS assessment within 6 months after baseline than in those with later assessment (OR 1.810, 95% CI 0.999-3.280; P=.050). The 2-year completion adherence to Web-based self-assessments did not differ between the low-frequency long questionnaires and a high-frequency short questionnaire, but the interval adherence was substantially higher for the low-frequency long questionnaires. Personal contact with a member of the research team regarding a clinically relevant professional-reported outcome early in the study might positively affect the long-term completion adherence in direct-to-patient studies. ©Peter Joseph Jongen, Ingrid E.H. Kremer, Elena Hristodorova, Silvia M.A.A. Evers, Anton Kool, Esther M van Noort, Mickaël Hiligsmann. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 21.07.2017.

EDITORIAL: Optical Fibre Sensors 18 (OFS-18)

NASA Astrophysics Data System (ADS)

Jones, Julian D. C.; Tatam, Ralph P.

2007-10-01

fibre optic gyroscope, conventionally taken to date from the first experimental demonstration by V Vali and R W Shorthill (1976 'Fibre ring interferometer' Appl. Opt. 15 1099-100). It is an indication of the health of the community that the successful maturity of some applications is complemented by the new technologies that will be the basis of the future development of the field, and here the content of this special issue is an interesting indication of likely areas of growth. Essentially all current fibre optic systems are based on solid, doped fused silica fibres, which are the basis of the world's telecommunications industry. However, over the last decade an exciting development has been micro-structured fibres, whose waveguiding properties owe as much to the structure of the fibre as to the materials from which they are made. The significance for sensing applications is considerable, with opportunities to achieve properties for dispersion, environmental sensitivity, wavelength range and power-handling quite different from the capabilities of conventional fibre. Thus it is not surprising that several of the papers in the issue (by Cordeiro, Martynkien, Bock, Wolinski, Michie, Digonnet and Kilic) are devoted to applications of such fibres—photonic crystal fibres (PCF), as they are often called. Digonnet's contribution is especially interesting, being concerned with the use of hollow-core photonic bandgap fibre to form a gyroscope, hence avoiding the many subtle non-linear optical effects that can degrade the performance of a conventional fibre gyroscope. PCF are not the only special fibres to feature in the issue: polymer fibres are of increasing interest for sensing applications (O'Keeffe, Kiesel, Kalli and Ashley), not least for their ability to withstand high levels of strain. In-fibre gratings continue to be a very important area in the field, and are well represented in the issue (Ni, González-Segura, Chen, Falate, Kamikawachi, Wang and Correia). We hope

Hydrologic regime alteration of a Mediterranean catchment under climate change projection

NASA Astrophysics Data System (ADS)

Sellami, Haykel; Benabdallah, Sihem; La Jeunesse, Isabelle; Herrmann, Frank; Vanclooster, Marnik

2014-05-01

. López-Moreno, J. I., Vicente-Serrano, S. M., Moran-Tejeda, E., Zabalza, J., Lorenzo-Lacruz, J., and García-Ruiz, J. M.: Impact of climate evolution and land use changes on water yield in the ebro basin, Hydrology and Earth System Sciences, 15, 311-322, 10.5194/hess-15-311-2011, 2011. Ludwig, R., Roson, R., Zografos, C., Kallis. Towards an inter-disciplinary research agenda on climate change, water and security in southern Europe and neighbouring countries. Environ. Sci. Policy. 14: 794-803, 10.1016/j.envsci.2011.04.003, 2011. Richter, B. D., Baumgartner, J.V., Powell, J., Braun, D. P.: Method for Assessing Hydrologic Alteration within Ecosystems, Conservation Biology, 10, 11, 1996. Schneider, C., Laizé, C. L. R., Acreman, M. C., and Flörke, M.: How will climate change modify river flow regimes in Europe? Hydrology and Earth System Sciences, 17, 325-339, 10.5194/hess-17-325-2013, 2013.

PREFACE: IUPAP C20 Conference on Computational Physics (CCP 2011)

NASA Astrophysics Data System (ADS)

Troparevsky, Claudia; Stocks, George Malcolm

2012-12-01

McCurdy (Lawrence Berkeley National Laboratory, US) Ingrid Mertig (Martin Luther University, Germany) Alejandro Muramatsu (Universitat Stuttgart, Germany) Richard Needs (Cavendish Laboratory, UK) Giuseppina Orlandini (University of Trento, Italy) Martin Savage (University of Washington, US) Thomas Schulthess (ETH, Switzerland) Dzidka Szotek (Daresbury Laboratory, UK) Hideaki Takabe (Osaka University, Japan) William M. Tang (Princeton University, US) James Vary (Iowa State, US) Enge Wang (Chinese Academy of Science, China) Jian-Guo Wang (Institute of Applied Physics and Computational Mathematics, China) Jian-Sheng Wang (National University, Singapore) Dan Wei (Tsinghua University, China) Tony Williams (University of Adelaide, Australia) Rudy Zeller (Julich, Germany) Conference Administrator: Ann Strange (ORNL)

Soluble VCAM-1/soluble ICAM-1 ratio is a promising biomarker for diagnosing endometriosis.

PubMed

Kuessel, L; Wenzl, R; Proestling, K; Balendran, S; Pateisky, P; Yotova; Yerlikaya, G; Streubel, B; Husslein, H

2017-04-01

were higher in normal peritoneum samples obtained from women with endometriosis compared to those from controls (P = 0.038 and P = 0.009). The mRNA levels of VCAM-1 were also higher in the eutopic endometrium samples obtained from women with endometriosis compared to controls (P = 0.018). With respect to serum protein levels, compared to controls, the women with endometriosis had lower serum levels of sICAM-1 (P = 0.042) and higher levels of sVCAM-1 (P < 0.001). Our analysis revealed that the serum levels of sVCAM-1 were not affected by lesion entity, menstrual cycle phase or disease severity. An receiver operating characteristics curve, calculated to determine whether preoperative serum sVCAM-1 concentration can be used to predict endometriosis, found an AUC of 0.868 with 80% specificity and 84% sensitivity at a cutoff value of 370 pg/ml. This predictive performance can be further improved by calculation of the sVCAM-1/sICAM-1 ratio, leading to an AUC of 0.929 with 86.7% specificity and 90.3% sensitivity at a cutoff ratio value of 1.55. Not applicable. The relatively small sample size in the expression analyses is a possible limitation of this study. Our findings could contribute to an improved understanding of the pathogenesis of endometriosis and the role of cell adhesion molecules. In addition, the results may lead to the development of new, non-invasive tools for diagnosing endometriosis. The ability to diagnose patients by measuring serum sVCAM-1 levels or the sVCAM-1/sICAM-1 ratio would have considerable clinical value. The Ingrid Flick Foundation (Grant no. FA751C0801), which played no role in the study design, data collection and analysis, decision to publish or preparation of the manuscript. The authors declare no competing interests. © The Author 2017. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com

A preface to the 70&70 Gravity Fest

NASA Astrophysics Data System (ADS)

Gutiérrez-Piñeres, A. C.; Montoya, E. A.; Núñez, L. A.

2017-03-01

fruitful collaboration which leads to the invention of the loop representation for Yang-Mills theories in 1986. Luis Gaucho Herrera is a versatile theoretical physicist with major contribution on the effect of anisotropy on the evolution of selfgravitating compact objects. He also pioneer in the heritage of symmetries within General Relativity and in the application of Extended Thermodynamics for Astrophysical scenarios, where he has very deep and important contributions isolating dissipation effects on relativistic systems. Recently, he has proposed alternative approaches to detect gravitational radiation using gyroscopes and about the relevance of super energy and super Poynting in General Relativity. Rodolfo Gambini is a profound physicist with contributions ranging from philosophy of science and foundations of quantum mechanics to lattice gauge theories to quantum gravity. He has also an active participation building public scientific policies in Uruguay and in recent years he has studied issues in the foundations of quantum mechanics, having developed the Montevideo Interpretation of Quantum Mechanics. He also found the exact solution of the quantum Einstein equations in loop quantum gravity for vacuum spherically symmetric space-times, which resolves the singularity inside black holes. Thanks to Dean of Facultad Ciencias Básicas Dr. Jorge Luis Muñiz and the hospitality of Ingrid Tamayo and Rosana Ávila members of the Educación Permanente staff of Universidad Tecnológica de Bolívar (Cartagena-Colombia) we met from 28th to 30th of September 2016. Among the researchers that have the opportunity to share visions with Rodolfo and Luis about Classical and Quantum Gravity we can mention: Iván Agullo (Louisiana State University, USA.), Miguel Alcubierre (Universidad Nacional Autónoma de México, México), Roberto Aquilano (Universidad de Rosario Argentina), Jaume Carot (Universitat de les Illes Balears, Spain), Alicia Di Prisco (Universidad Central de Venezuela

"Missing Link" Revealing Fast-Spinning Pulsar Mysteries

NASA Astrophysics Data System (ADS)

2009-05-01

telescope during a large sky survey in 1998, and had been observed in visible light by the Sloan Digital Sky Survey in 1999, revealing a Sun-like star. When observed again in 2000, the object had changed dramatically, showing evidence for a rotating disk of material, called an accretion disk, surrounding the neutron star. By May of 2002, the evidence for this disk had disappeared. "This strange behavior puzzled astronomers, and there were several different theories for what the object could be," said Ingrid Stairs of the University of British Columbia, who has been visiting the Australia Telescope National Facility and Swinburne University this year. The 2007 GBT observations showed that the object is a millisecond pulsar, spinning 592 times per second. "No other millisecond pulsar has ever shown evidence for an accretion disk," Archibald said. "We know that another type of binary-star system, called a low-mass X-ray binary (LMXB), also contains a fast-spinning neutron star and an accretion disk, but these don't emit radio waves. We've thought that LMXBs probably are in the process of getting spun up, and will later emit radio waves as a pulsar. This object appears to be the 'missing link' connecting the two types of systems," she explained. "It appears this thing has flipped from looking like an LMXB to looking like a pulsar, as it experienced an episode during which material pulled from the companion star formed an accretion disk around the neutron star. Later, that mass transfer stopped, the disk disappeared, and the pulsar emerged," said Scott Ransom of the NRAO. The scientists have studied J1023 in detail with the GBT, with the Westerbork radio telescope in the Netherlands, with the Arecibo radio telescope in Puerto Rico, and with the Parkes radio telescope in Australia. Their results indicate that the neutron star's companion has less than half the Sun's mass, and orbits the neutron star once every four hours and 45 minutes. "This system gives us an unparalled 'cosmic

Astronomers Discover Fastest-Spinning Pulsar

NASA Astrophysics Data System (ADS)

2006-01-01

discovered in 1982. For reference, the fastest speeds of common kitchen blenders are 250-500 Hz. The scientists say the object's fast rotation speed means that it cannot be any larger than about 20 miles across. According to Hessels, "If it were any larger, material from the surface would be flung into orbit around the star." The scientists' calculation assumed that the neutron star contains less than two times the mass of the Sun, an assumption that is consistent with the masses of all known neutron stars. The spinning pulsar has a companion star that orbits it once every 26 hours. The companion passes in front of the pulsar, eclipsing the pulsar about 40 percent of the time. The long eclipse period, probably due to bloating of the companion, makes it difficult for the astronomers to learn details of the orbital configuration that would allow them to precisely measure the masses of the pulsar and its companion. "If we could pin down these masses more precisely, we could then get a better limit on the size of the pulsar. That, in turn, would then give us a better figure for the true density inside the neutron star," explained Ingrid Stairs, an assistant professor at the University of British Columbia and another collaborator on the work. Competing theoretical models for the types and distributions of elementary particles inside neutron stars make widely different predictions about the pressure and density of such an object. "We want observational data that shows which models fit the reality of nature," Hessels said. If the scientists can't use PSR J1748-2446ad to do that, they are hopeful some of its near neighbors will yield the data they seek. Using the GBT, the astronomers so far have found 30 new fast "millisecond pulsars" in the cluster Terzan 5, making 33 pulsars known in the cluster in total. This is the largest number of such pulsars ever found in a single globular cluster. Dense globular clusters of stars are excellent places to find fast-rotating millisecond

Youngest Radio Pulsar Revealed with Green Bank Telescope

NASA Astrophysics Data System (ADS)

2002-04-01

mine for years to come," noted Camilo. "We can very precisely measure how its rate of rotation changes over time, potentially inferring fundamental clues about what causes a magnetized neutron star to spin down. We also will make valuable comparisons to the X-ray data, which may help us determine exactly how these objects generate and emit radiation." The researchers also point to the fact that this discovery bodes well for the GBT being able to study additional young pulsars that have previously escaped detection. "By using this magnificent new telescope, we should be able to discover other very young pulsars that we surmise are there, but are simply too weak to detect by any other means," said Camilo. "Measuring the luminosity and spectrum of a large sample of these stars will be crucial for making an accurate census of pulsars in our Galaxy." The researchers used the new Berkeley-Caltech Pulsar Machine to process the signals from the GBT and record them for later analysis. The group led by Camilo in this investigation consists also of: Ingrid H. Stairs (NRAO Green Bank, West Virginia); Duncan R. Lorimer, Michael Kramer, Maura A. McLaughlin (University of Manchester, Jodrell Bank Observatory, Cheshire, U.K.); Donald C. Backer (University of California, Berkeley); Scott M. Ransom (McGill University, Montreal, Canada); Bernd Klein, Richard Wielebinski, Peter Muller (Max-Planck-Institut fur Radioastronomie, Bonn, Germany); and Zaven Arzoumanian (Universities Space Research Association/NASA-Goddard Space Flight Center, Greenbelt, Maryland). The GBT is the world's largest fully steerable radio telescope. It was dedicated on August 25, 2000. The National Radio Astronomy Observatory is a facility of the National Science Foundation, operated under cooperative agreement by Associated Universities, Inc.

TH-C-204-01: Vision for Medical Physics and Status of Current Initiatives

DOE Office of Scientific and Technical Information (OSTI.GOV)

Williamson, J.

In this presentation, the Editors will outline our vision for the future of Medical Physics and review recent work-in-progress initiatives to implement this vision. Finally, we will close with guidance to authors on how to write a good Medical Physics paper. A major focus will be the transition to a new publisher in 2017 following a more than 40-year association with American Institute of Physics Publishing (AIPP). Vision for Medical Physics and status of current initiatives: Jeff Williamson, Editor-in-Chief The broad vision of Medical Physics is “to continue the Journal’s tradition of publishing the very best science that propels ourmore » discipline forward and improves our contribution to patient care.” More concretely, the Journal should be the preeminent forum for exchange of cutting edge medical physics science. We seek to identify the best contributions in (a) high impact clinical physics innovations; (b) clinical translation and validation of basic science innovations; and (c) cutting edge basic science developments with potential for patient care improvements. Among the challenges and opportunities, we face are: electronic-only and open access publishing; competition from new radiological science journals; trends towards more interactive, social-media based scientific communities; and diversification of the medical physics research, authorship, and readership domains, including clinical applications quite foreign to core ABR clinical competencies. Recently implemented and ongoing initiatives include: Revised Table of Contents (TOC) and more contemporary topical submission categories Structured review template in HTML format Comprehensive hierarchical taxonomy for identifying reviewer expertise Formal process for soliciting high quality and impact Review and Vision 20/20 Articles We have recruited four Review Article Co-editors: John Rowlands and Ingrid Reiser (imaging physics) and Joao Seco and Tim Zhu (therapy physics). The Co-Editors will

TH-C-204-00: Medical Physics Workshop: An Update On the Journal’s Improvement Activities and Guidance On Writing and Reviewing Papers

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

In this presentation, the Editors will outline our vision for the future of Medical Physics and review recent work-in-progress initiatives to implement this vision. Finally, we will close with guidance to authors on how to write a good Medical Physics paper. A major focus will be the transition to a new publisher in 2017 following a more than 40-year association with American Institute of Physics Publishing (AIPP). Vision for Medical Physics and status of current initiatives: Jeff Williamson, Editor-in-Chief The broad vision of Medical Physics is “to continue the Journal’s tradition of publishing the very best science that propels ourmore » discipline forward and improves our contribution to patient care.” More concretely, the Journal should be the preeminent forum for exchange of cutting edge medical physics science. We seek to identify the best contributions in (a) high impact clinical physics innovations; (b) clinical translation and validation of basic science innovations; and (c) cutting edge basic science developments with potential for patient care improvements. Among the challenges and opportunities, we face are: electronic-only and open access publishing; competition from new radiological science journals; trends towards more interactive, social-media based scientific communities; and diversification of the medical physics research, authorship, and readership domains, including clinical applications quite foreign to core ABR clinical competencies. Recently implemented and ongoing initiatives include: Revised Table of Contents (TOC) and more contemporary topical submission categories Structured review template in HTML format Comprehensive hierarchical taxonomy for identifying reviewer expertise Formal process for soliciting high quality and impact Review and Vision 20/20 Articles We have recruited four Review Article Co-editors: John Rowlands and Ingrid Reiser (imaging physics) and Joao Seco and Tim Zhu (therapy physics). The Co-Editors will

TH-C-204-02: Improving Manuscript Quality Via Structured Reviews, Enhanced Scientific Category Taxonomy, and Outreach

DOE Office of Scientific and Technical Information (OSTI.GOV)

Das, S.

In this presentation, the Editors will outline our vision for the future of Medical Physics and review recent work-in-progress initiatives to implement this vision. Finally, we will close with guidance to authors on how to write a good Medical Physics paper. A major focus will be the transition to a new publisher in 2017 following a more than 40-year association with American Institute of Physics Publishing (AIPP). Vision for Medical Physics and status of current initiatives: Jeff Williamson, Editor-in-Chief The broad vision of Medical Physics is “to continue the Journal’s tradition of publishing the very best science that propels ourmore » discipline forward and improves our contribution to patient care.” More concretely, the Journal should be the preeminent forum for exchange of cutting edge medical physics science. We seek to identify the best contributions in (a) high impact clinical physics innovations; (b) clinical translation and validation of basic science innovations; and (c) cutting edge basic science developments with potential for patient care improvements. Among the challenges and opportunities, we face are: electronic-only and open access publishing; competition from new radiological science journals; trends towards more interactive, social-media based scientific communities; and diversification of the medical physics research, authorship, and readership domains, including clinical applications quite foreign to core ABR clinical competencies. Recently implemented and ongoing initiatives include: Revised Table of Contents (TOC) and more contemporary topical submission categories Structured review template in HTML format Comprehensive hierarchical taxonomy for identifying reviewer expertise Formal process for soliciting high quality and impact Review and Vision 20/20 Articles We have recruited four Review Article Co-editors: John Rowlands and Ingrid Reiser (imaging physics) and Joao Seco and Tim Zhu (therapy physics). The Co-Editors will

TH-C-204-03: Writing Good Scientific Papers and Responding to Critiques

DOE Office of Scientific and Technical Information (OSTI.GOV)

Goodsitt, M.

In this presentation, the Editors will outline our vision for the future of Medical Physics and review recent work-in-progress initiatives to implement this vision. Finally, we will close with guidance to authors on how to write a good Medical Physics paper. A major focus will be the transition to a new publisher in 2017 following a more than 40-year association with American Institute of Physics Publishing (AIPP). Vision for Medical Physics and status of current initiatives: Jeff Williamson, Editor-in-Chief The broad vision of Medical Physics is “to continue the Journal’s tradition of publishing the very best science that propels ourmore » discipline forward and improves our contribution to patient care.” More concretely, the Journal should be the preeminent forum for exchange of cutting edge medical physics science. We seek to identify the best contributions in (a) high impact clinical physics innovations; (b) clinical translation and validation of basic science innovations; and (c) cutting edge basic science developments with potential for patient care improvements. Among the challenges and opportunities, we face are: electronic-only and open access publishing; competition from new radiological science journals; trends towards more interactive, social-media based scientific communities; and diversification of the medical physics research, authorship, and readership domains, including clinical applications quite foreign to core ABR clinical competencies. Recently implemented and ongoing initiatives include: Revised Table of Contents (TOC) and more contemporary topical submission categories Structured review template in HTML format Comprehensive hierarchical taxonomy for identifying reviewer expertise Formal process for soliciting high quality and impact Review and Vision 20/20 Articles We have recruited four Review Article Co-editors: John Rowlands and Ingrid Reiser (imaging physics) and Joao Seco and Tim Zhu (therapy physics). The Co-Editors will

Star Cluster Buzzing With Pulsars

NASA Astrophysics Data System (ADS)

2005-01-01

left after a massive star explodes as a supernova at the end of its life. The pulsars in Terzan 5 are the product of a complex history. The stars in the cluster formed about 10 billion years ago, the astronomers say. Some of the most massive stars in the cluster exploded and left the neutron stars as their remnants after only a few million years. Normally, these neutron stars would no longer be seen as swiftly-rotating pulsars: their spin would have slowed because of the "drag" of their intense magnetic fields until the "lighthouse" effect is no longer observable. The Green Bank Telescope The Robert C. Byrd Green Bank Telescope CREDIT: NRAO/AUI/NSF (Click on image for GBT gallery) However, the dense concentration of stars in the cluster gave new life to the pulsars. In the core of a globular cluster, as many as a million stars may be packed into a volume that would fit easily between the Sun and our nearest neighbor star. In such close quarters, stars can pass near enough to form new binary pairs, split apart such pairs, and binary systems even can trade partners, like an elaborate cosmic square dance. When a neutron star pairs up with a "normal" companion star, its strong gravitational pull can draw material off the companion onto the neutron star. This also transfers some of the companion's spin, or angular momentum, to the neutron star, thereby "recycling" the neutron star into a rapidly-rotating millisecond pulsar. In Terzan 5, all the pulsars discovered are rotating rapidly as a result of this process. Astronomers previously had discovered three pulsars in Terzan 5, some 28,000 light-years distant in the constellation Sagittarius, but suspected there were more. On July 17, 2004, Ransom and his colleagues used the GBT, and, in a 6-hour observation, found 14 new pulsars, the most ever found in a single observation. "This was possible because of the great sensitivity of the GBT and the new capabilities of our backend processor," said Ingrid Stairs, a professor at the

PERSPECTIVE: Snow matters in the polar regions

NASA Astrophysics Data System (ADS)

Sodeau, John

2010-03-01

Antarctica is not quite as chemically pristine as might sometimes be thought (Jones et al 2008). For example, as elsewhere, reduced sulfur species such as dimethylsulfide (DMS) are emitted from biogenic marine sources at the poles (Read et al 2008). Somewhat less well known is that inland (as opposed to coastal) field campaigns have also detected, within the Antarctic boundary layer (ABL), emissions containing unexpectedly high levels of diverse, oxidizing chemicals such as NOx, nitrate ions, formaldehyde, ozone and hydrogen peroxide (Honrath et al 1999, Hutterli et al 2004, Sumner and Shepson 1999). And then there are the halogen-containing compounds (Simpson et al 2007). The transformation of DMS to sulfate aerosols capable of acting as cloud condensation nuclei often proceeds via one main oxidized product of DMS, namely methanesulfonic acid (MSA). Two specific reactions have been well studied to date in this regard, namely DMS plus either OH or NO3 radicals. Corresponding reactions with halogen radicals, which also contribute to the oxidizing capacity of our atmosphere, have generally been considered to be of less importance. The reason for this view is that even though the reactivity of bromine- and iodine-containing radicals is much greater than that of OH, the halogens were thought to be relatively scarce in the polar atmosphere. However both BrO (and IO) have been detected in the Antarctic CHABLIS campaign, as discussed in depth in the Atmospheric Chemistry and Physics special issue of 2008, see Jones et al (2008). It was subsequently shown that calculated MSA production from the DMS/BrO reaction may be about an order of magnitude greater than when the OH radical was the oxidizing reactant. The recent analytical measurements by Antony et al (2010) of MSA, Br and NO3 found in snow along the Ingrid Christensen Coast of East Antarctica are important in the above field context. Hence it would appear that the concentrations of these ions in ice-cap sites are up