Sample records for kapal nuklir non-militer

  1. Discursive archaeology: constituting knowledge of militant nurses in trade associations.

    PubMed

    Almeida, Deybson Borba de; Silva, Gilberto Tadeu Reis da; Freitas, Genival Fernandes de; Padilha, Maria Itayra; Almeida, Igor Ferreira Borba de

    2018-05-01

    To analyze the constituting knowledge of militant nurses in trade associations. Historical research, based on the oral history method, with a qualitative approach carried out with 11 nurses who are/were militants for professional issues since the 1980s in the state of Bahia. The data collected through semi-structured interviews were organized in the software n-vivo 10 and analyzed based on dialectical hermeneutics. We identified pedagogical, administrative, public health, sociological, and trade union background knowledge as constituent of militant individuals. Final considerations: The constituting knowledge of militant nurses are inscribed in the Social Sciences, distanced from biomedical knowledge and power, pointing at ways for structuring nursing curricula. We identified the Brazilian Association of Nursing as a space for political formation.

  2. Oil terrorism-militancy link: Mediating role of moral disengagement in emergency and crisis management.

    PubMed

    Mafimisebi, Oluwasoye Patrick; Thorne, Sara

    2015-01-01

    The controversial issues of terrorism and militancy have generated contemporary interests and different interpretations have emerged on how to combat and manage these dangerous events. This study widens understanding of moral disengagement mechanism application in the perpetuation of inhumanities within the context of oil terrorist and militant behaviors. The research findings and model are explicit on how people form moral evaluations of agents who are forced to make morally relevant decisions over times in context of crisis situations. Quite crucially, understanding the context of terrorism and militancy provides policymakers, emergency and crisis managers better analysis and response to such events. The research fundamental purpose was to investigate the mediating role of moral disengagement on delinquency of oil terrorism and militancy; and considered implications for emergency and crisis management practices. The study found that situational-induced crises such as oil terrorism and militancy were sufficient to account for an individual's misdeeds and unethical or inhumane decisions made under frustration and agitation may be perceived as less indicative of one's fundamental character. Findings suggest that more repugnant delinquencies could have been committed in the name of justice than in the name of injustice, avenues for future research. In context, the result of the moral disengagement scale shows that morality of delinquency (oil terrorism and militancy) is accomplished by cognitively redefining the morality of such acts. The main finding is that people in resistance movements are rational actors making rational choices. The authors argue that theorists, policymakers, and practitioners must give meaningful attention to understanding the multidimensional nature of emergency, crisis and disaster management for better strength of synthesis between theory and practice. The research is concluded by thorough examination of the implication and limitations for

  3. Contemporary militant extremism: a linguistic approach to scale development.

    PubMed

    Stankov, Lazar; Higgins, Derrick; Saucier, Gerard; Knežević, Goran

    2010-06-01

    In this article, the authors describe procedures used in the development of a new scale of militant extremist mindset. A 2-step approach consisted of (a) linguistic analysis of the texts produced by known terrorist organizations and selection of statements from these texts that reflect the mindset of those belonging to these organizations and (b) analyses of the structural properties of the scales based on 132 selected statements. Factor analysis of militant extremist statements with participants (N = 452) from Australia, Serbia, and the United States produced 3 dimensions: (a) justification and advocacy of violence (War factor), (b) violence in the name of God (God factor), and (c) blaming Western nations for the problems in the world today (West factor). We also report the distributions of scores for the 3 subscales, mean differences among the 3 national samples, and correlations with a measure of dogmatism (M. Rokeach, 1956).

  4. Militancy and Accommodativeness in Teachers' Negotiations: Two Ontario Surveys

    ERIC Educational Resources Information Center

    Fris, J.

    1976-01-01

    Reports findings of two surveys of Ontario elementary and secondary teachers that measured teachers' attitudes regarding collective bargaining tactics and classified teachers' responses according to their militancy or accomodativeness. Available from Department of Educational Administration, The University of Alberta, Edmonton, Alberta, Canada T6G…

  5. Contemporary Militant Extremism: A Linguistic Approach to Scale Development

    ERIC Educational Resources Information Center

    Stankov, Lazar; Higgins, Derrick; Saucier, Gerard; Knezevic, Goran

    2010-01-01

    In this article, the authors describe procedures used in the development of a new scale of militant extremist mindset. A 2-step approach consisted of (a) linguistic analysis of the texts produced by known terrorist organizations and selection of statements from these texts that reflect the mindset of those belonging to these organizations and (b)…

  6. Militant Extremist Mind-Set: Proviolence, Vile World, and Divine Power

    ERIC Educational Resources Information Center

    Stankov, Lazar; Saucier, Gerard; Knezevic, Goran

    2010-01-01

    In the present article, the authors report on the development of a scale for the measurement of the militant extremist mind-set. A previous pilot study identified 56 statements selected from writings of various terrorist groups as well as from psychological, historical, and political texts on terrorism. These statements, together with measures of…

  7. Teachers' Militancy, the Potential for It, and Perceptions of School Organizational Structure.

    ERIC Educational Resources Information Center

    Gans, Thomas G.

    This study examined the degree to which the structure of school organizations and the personal dispositions of teachers are related to the occurrence of militant conflict within or against school organization. This study was a part of a larger project studying the process of instituting change in school organization. A four-part questionnaire…

  8. A Cause for Concern The Spread of Militant Islam in East Africa

    DTIC Science & Technology

    2017-01-11

    support militant Islamist groups .110 Qatar has likewise been supporting Salafists financially since the late 1970s and, according to Hussein Solomon ...a Tanzanian national, and Abdirahim Mohamed Abdullahi, a Kenyan national, along with four other attackers assessed to be of Kenyan origin, departed...doubt that extremist groups are intimately familiarly with these socioeconomic, cultural, and ethnic levers and understand how to manipulate them. But

  9. Positive and Negative Effects of Chicano Militancy on the Education of the Mexican American.

    ERIC Educational Resources Information Center

    Gonzalez, Nancie L.

    Types of organizations (e.g., conservative, militant, those furthering a specific cause, youth organizations, or social club organizations) involved in Chicano movements operating in the 5 southwestern states and other areas with large numbers of Mexican Americans are described in this paper. Such organizations as the League of United Latin…

  10. Democratic Values and Support for Militancy: Evidence from a National Survey of Pakistan

    DTIC Science & Technology

    2011-06-14

    suggests that theories about the palliative role of democratic values need to take careful consideration of political context. Since at least the...democratic representation , and other liberal democratic values. In South Asia and the Middle East today, many militant groups claim to be defending...freedom, fighting for self- representation , and mobilizing against what they perceive to be corrupt governments. Moreover, the populations from which

  11. Democratic Values and Support for Militant Politics: Evidence from a National Survey of Pakistan

    DTIC Science & Technology

    2012-11-27

    years, and on the nature of competition between governments and militant groups in some regions, suggests that theories about the palliative role of...democratic values need to take political context into careful consideration. Beginning at least with the American Revolution, there has been no...shortage of political movements that have rallied their followers to kill, and to risk death, in the name of freedom, democratic representation , and

  12. Why have the majority of recent polio cases occurred in countries affected by Islamist militancy? A historical comparative analysis of the political determinants of polio in Nigeria, Somalia, Pakistan, Afghanistan and Syria.

    PubMed

    Kennedy, Jonathan

    2016-01-01

    This article aims to understand why the last few areas where polio remains are affected by armed conflicts involving militant organizations that use Islam to legitimize their activities. The first section critically analyses the argument that Muslims' animosity towards polio vaccination programmes is a consequence of their irrational, backward, anti-Western theology. This argument is depoliticizing, ahistorical and orientalist. Moreover, it does not explain why Islamist militant groups' attitudes to polio vaccination campaigns vary between countries. The second section analyses official documents, newspaper articles, interviews and historical and ethnographic accounts to understand the relationship between Islamist militant groups and polio in five countries - Nigeria, Somalia, Pakistan, Afghanistan and Syria - that account for 95% of the world's polio cases since 2012. I demonstrate that specific political grievances related to the postcolonial state and/or foreign military intervention help to explain variations in militant groups' attitudes to polio vaccination programmes. The paper concludes by considering the policy implications of the analysis. Improved access for polio vaccinators is not predicated on military victory against the militants but securing support of de facto political leaders. This can be achieved by developing a better understanding of the specific sociopolitical contexts in which immunization programmes operate.

  13. The Precarious Void of Extremist Ideology in Bangladesh: A Path Towards Understanding the Phenomenology of Militant Violence

    DTIC Science & Technology

    2012-06-01

    55 viii Figure 1 Map of Bangladesh x 2 The Muslim World 43 3 Terrorist Incidents by Militant...identities shape the population’s view of the outside world .7 Regional expertise beyond Af-Pak Hands has become a national security imperative in a...post-9/11 world , in which increased focus must be placed on all of South Asia. The region contains more than half the world’s Muslim population within

  14. Militant extremist mind-set: Proviolence, Vile World, and Divine Power.

    PubMed

    Stankov, Lazar; Saucier, Gerard; Knežević, Goran

    2010-03-01

    In the present article, the authors report on the development of a scale for the measurement of the militant extremist mind-set. A previous pilot study identified 56 statements selected from writings of various terrorist groups as well as from psychological, historical, and political texts on terrorism. These statements, together with measures of personality, social attitudes, values, and social cynicism, were administered to participants from 9 countries (N = 2,424). A series of exploratory factor analyses of 56 statements produced 3 factors: Proviolence, Vile World, and Divine Power. Correlations of these factors with external variables indicate that Divine Power is a traditional religiosity scale, whereas Proviolence and Vile World scales cannot be accounted for by the existing psychological constructs. The distribution of scores on the Proviolence scale is skewed, indicating that the majority of participants disapprove of this attitude. The authors also present means for the countries included in the analysis. Participants from Malaysia endorse Vile World and Divine Power statements stronger than participants from other countries. The 3 Asian countries (China, Korea, and Malaysia) endorse Proviolence more strongly than countries from other parts of the world. PsycINFO Database Record (c) 2010 APA, all rights reserved.

  15. SOCIO-BEHAVIORALCONSIDERATIONS IN THE ROLE OF MILITANT EXTREMISM.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bernard, Michael Lewis; Backus, George A.; Beyeler, Walter E.

    This paper discusses relevant findings and theories regarding the role of ideology, culture, and context in shaping the behaviors of individuals within violent social movements. Accordingly, this focus concerns the comparative weight placed on ideology and culture (expressed principles and motives) versus external factors as chief influencers for the propensity of individuals to act outside of the norms of society and politics by resorting to violent behaviors. In doing so, we have drawn upon theory from anthropology, behavioral economics, political science, psychology, and sociology to better understand how these variables give birth to and nurture militant social movements. F umore » r t h e r d i s s e m i n a t i o n o n l y a s a u t h o r i z e d t o U . S . G o v e r n m e n t a g e n c i e s a n d t h e i r c o n t r a c t o r s ; o t h e r r e q u e s t s s h a l l b e a p p r o v e d b y t h e o r i g i n a t i n g f a c i l i t y o r h i g h e r D O E p r o g r a m m a t i c a u t h o r i t y .« less

  16. Socio-behavioral considerations in the role of militant extremism

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bernard, Michael Lewis; Backus, George A.; Beyeler, Walter E.

    This paper discusses relevant findings and theories regarding the role of ideology, culture, and context in shaping the behaviors of individuals within violent social movements. Accordingly, this focus concerns the comparative weight placed on ideology and culture (expressed principles and motives) versus external factors as chief influencers for the propensity of individuals to act outside of the norms of society and politics by resorting to violent behaviors. In doing so, we have drawn upon theory from anthropology, behavioral economics, political science, psychology, and sociology to better understand how these variables give birth to and nurture militant social movements. F umore » r t h e r d i s s e m i n a t i o n o n l y a s a u t h o r i z e d t o U . S . G o v e r n m e n t a g e n c i e s a n d t h e i r c o n t r a c t o r s ; o t h e r r e q u e s t s s h a l l b e a p p r o v e d b y t h e o r i g i n a t i n g f a c i l i t y o r h i g h e r D O E p r o g r a m m a t i c a u t h o r i t y .« less

  17. Don't tread on me: masculine honor ideology in the U.S. and militant responses to terrorism.

    PubMed

    Barnes, Collin D; Brown, Ryan P; Osterman, Lindsey L

    2012-08-01

    Using both college students and a national sample of adults, the authors report evidence linking the ideology of masculine honor in the U.S. with militant responses to terrorism. In Study 1, individuals' honor ideology endorsement predicted, among other outcomes, open-ended hostile responses to a fictitious attack on the Statue of Liberty and support for the use of extreme counterterrorism measures (e.g., severe interrogations), controlling for right-wing authoritarianism, social dominance orientation, and other covariates. In Study 2, the authors used a regional classification to distinguish honor state respondents from nonhonor state respondents, as has traditionally been done in the literature, and showed that students attending a southwestern university desired the death of the terrorists responsible for 9/11 more than did their northern counterparts. These studies are the first to show that masculine honor ideology in the U.S. has implications for the intergroup phenomenon of people's responses to terrorism.

  18. Factors That Militate against Non-Traditional, Technical College Students Enrolling in an Initial Remedial Course

    ERIC Educational Resources Information Center

    Brandau, Ann M.

    2013-01-01

    While there has been a substantial amount of research focused on underprepared non-traditional students who have withdrawn or persisted in remedial education coursework, little research has been conducted on underprepared, non-traditional students who choose not to enroll after being referred to remedial studies. In light of this gap in the…

  19. Marketing strategies of hospital service organizations in Nigeria: a study of selected privately owned hospitals in Port Harcourt.

    PubMed

    Okwandu, Gabriel A

    2002-01-01

    This study was centered on the identification of the marketing strategies of hospitals and the factors that militate against their effective adoption and implementation. A total of 80 hospitals in Port Harcourt responded to a structured questionnaire administered on them. It was found, among other things, that many hospital organizations apply marketing strategies, and that hospitals that adopt effective marketing strategies perform better than those that do not. Some of the factors militating against the effective adoption and implementation of marketing strategies include lack of planning, lack of top management support, and non-utilization of all the promotional mix elements.

  20. An Educology of Peace Education: Formulating a Strategy for the Promotion of Non-Violent Conflict Resolution in a Democracy

    ERIC Educational Resources Information Center

    Mallum, Jane O.

    2002-01-01

    The world today is fraught with violence and conflicts. This state of affairs is made all the more dangerous by the development of nuclear technology and the possibility of dissemination of military applications of this technology to unstable countries and militant terrorists. At the same time, there has been a rapid diffusion of democratization…

  1. The Attitudes of Anglophone and Francophone Cameroonians towards Cameroon English as a Model of English Language Teaching and Learning in Cameroon

    ERIC Educational Resources Information Center

    Atechi, Samuel; Angwah, Julius

    2016-01-01

    Teachers of English in Cameroon are proficient speakers of Cameroon English and their non-native status militates against their usage of Standard British English in the English language classrooms. This makes the attainment of British English thorny and perhaps impossible in Cameroon. Standing on that premise, we were motivated to find out…

  2. Chile Informed Question Paper - Military

    DTIC Science & Technology

    2003-01-01

    superior military strength and regional economic integration. Internally, Chile also faces little threat; however, militants from the Mapuche ...considered a significant threat.11 The most significant internal security concern is the ongoing campaign by Mapuche indigenous community militants to

  3. Who Gets Designated a Terrorist and Why?

    ERIC Educational Resources Information Center

    Beck, Colin J.; Miner, Emily

    2013-01-01

    This study examines formal terrorism designations by governments through the lens of organization studies research on categorization processes. It is argued that designations hinge on markers from the organizational profile of a militant group. Using cross-sectional data on militant organizations and designations by the United States, the United…

  4. Pakistan, Madrassas, and Militancy

    DTIC Science & Technology

    2006-12-01

    19 Uzma Anzar. Islamic Education: a brief history of madrassa with comments on curricula and current pedagogical practices. Retrieved May 23...curricula and current pedagogical practices. 3. 23 Nashabe, 19. 24 Hitti, 628. 25 Ali, 16. 26 Hitti, 628. 27 Ibid., 410 28 Anzar, 3. 10 The Nizamiyah...and its accompanying mythic beliefs and rituals. Deobandis do not oppose mysticism altogether but did argue that adherence to the Islamic law

  5. Social Justice Activism: Feminism and Strategies for Action

    ERIC Educational Resources Information Center

    Fernflores, Rachel

    2016-01-01

    Success in social justice activism often hinges on judging when to employ the most effective strategy for action. Strategies for action include militancy, peaceful protest, and sometimes, engaging in a longer term program of "marginal gains." The militant feminism of many 19th century suffragettes, such as Emmeline Pankhurst, is a good…

  6. Enacting Red Power: The Consummatory Function in Native American Protest Rhetoric.

    ERIC Educational Resources Information Center

    Lake, Randall A.

    1983-01-01

    Analyzes the American Indian Movement (AIM) with respect to (1) the role of tradition in AIM demands; (2) militant Indian rhetoric as a form of ritual self-address; (3) how Indian religious/cultural beliefs restrict the ability of language to persuade Whites; and (4) how militant Indian rhetoric fulfills its function. (PD)

  7. Unconventional Warfare and Counterinsurgency in Pakistan: A Brief History

    DTIC Science & Technology

    2012-11-01

    inter-connected. Punjabi Pakistani militants with sophisticated asymmetric warfare training and experience fighting Indian forces in Kashmir...factions. These Punjabi Pakistani militants would prove to be some of the most dangerous opponents of the government after 2006. From 2003 to 2006, the...68 Khan. “Untangling the Punjabi Taliban Network”. CTC Sentinel, March 2010; Franco, “Tehrik-e-Taliban Pakistan.” 69 Iqbal

  8. Combating Transnational Terrorism in Southeast Asia

    DTIC Science & Technology

    2003-06-06

    terrorist organization to the list: the Malaysian militant Islamic group Jemaah Islamiah. This example underscores how little the U.S. really knows about... Malaysian government is going to start videotaping sermons at six mosques where militant imams have been preaching anti-government messages. What will...disturbances was evident the symbolic character of the targets selected--foreign clubs and hotels, bars, cinemas and restaurants: establishments where

  9. Network Science Center Research Team’s Visit to Kampala, Uganda

    DTIC Science & Technology

    2013-04-15

    Leader • Someone in Social Network • Commercial Bank • White Collar Professional • Military Leader 16 | P a g e Network Science Center, West Point www.netscience.usma.edu 845.938.0804 ...regions, where the Lord’s Resistance Army 2 | P a g e Network Science Center, West Point www.netscience.usma.edu 845.938.0804 (LRA), a militant...Non-Governmental Organizations. Teddy Ruge Kanjokya Road in Kamwokya 3 | P a g e Network Science Center, West Point

  10. Strategic Delusions - The Cold Start Doctrine: Proactive Strategy

    DTIC Science & Technology

    2016-05-26

    recent tactical strike in Myanmar is miscued as a precursor for times to come in the regional context.10 These tactical actions also known as Hot...Attacks Militant Camps in Myanmar , Wall Street Journal, June 10, 2015, accessed August 24, 2015, http://www.wsj.com/articles/indian-army-attacks...militant-camps-in- myanmar -1433927858. 7 imperatives associated with the Indian PAS and its validation through the framework of strategy and the

  11. Militant Ideology Atlas: Research Compendium

    DTIC Science & Technology

    2006-11-01

    since I thought it was interesting the source author was using a title that was reminiscent of titles in the Hebrew bible even though this is the...disenfranchised youth in Jordanian prison and elsewhere. Notes: See English -language materials on Maqdisi’s website: http://www.revivingislam.com...Ibn Taymiyya’s teachings, translated into many languages, including English ("Book of Emaan According to Ibn Taymiyya"). Notes: One site calls

  12. Virtue and Vice: Morality Police and Social Control in Islamic Regimes

    DTIC Science & Technology

    2017-12-01

    religious, and militant groups since its emergence in 1994. Because of this, the forces of the MPVPV were employed to exert control over the behavior of...wounds.393 Men were also subject to a strict dress and appearance code. Once the Taliban seized control of Kabul, the group mandated that every man...aggressive campaign to establish control over hostile populations. In the United States’ ongoing conflict with militant groups such as the Taliban

  13. From Militant Voices to Militant Irony: Examining Identity, Memory and Conflict in the Basque Country

    PubMed Central

    Brescó de Luna, Ignacio

    2017-01-01

    Collective memory and identity so often go hand in hand with conflicts. Alongside the use of violence, conflicts unfold against the backdrop of different narratives about the past through which groups constantly remind themselves of the supposed origin of the conflict, and consequently, what position individuals are expected to take as members of the group. Narratives – as symbolic tools for interpreting the past and the present, as well as happenings that have yet to occur – simultaneously underpin, and are underpinned by, the position held by each warring faction. Drawing on previous works, this paper compares different versions of the 2016 truce period in the Basque Country stemming from three subjects identified, to varying degrees, with the main political actors involved in that conflict. These three cases have been selected from a total of 16 participants who were asked to define the Basque conflict and to provide an account of the 2006 truce period by using 23 documents taken from different Spanish newspapers. On the one hand, the results show two narratives reproducing the versions of two of the main political actors involved in the conflict, and on the other hand, a narrative characterized by a more personal and ironic appropriation of those versions. Results are discussed vis-à-vis the use of irony in history teaching in increasingly plural societies. PMID:28904601

  14. Recommendations to mitigate against human health risks incurred due to energetic particle irradiation beyond low earth orbit/BLEO

    NASA Astrophysics Data System (ADS)

    McKenna-Lawlor, Susan; Bhardwaj, Anil; Ferrari, Franco; Kuznetsov, Nikolay; Lal, Ajay K.; Li, Yinghui; Nagamatsu, Aiko; Nymmik, Rikho; Panasyuk, Michael; Petrov, Vladislav; Reitz, Günther; Pinsky, Lawrence; Shukor, Muszaphar (Sheikh); Singhvi, Ashok K.; Straube, Ulrich; Tomi, Leena; Lawrence, Townsend

    2015-04-01

    An account is provided of the main sources of energetic particle radiation in interplanetary space (Galactic Cosmic Radiation and Solar Energetic Particles) and career dose limits presently utilized by NASA to mitigate against the cancer and non-cancer effects potentially incurred by astronauts due to irradiation by these components are presented. Certain gaps in knowledge that presently militate against mounting viable human exploration in deep space due to the inherent health risks are identified and recommendations made as to how these gaps might be closed within a framework of global international cooperation.

  15. Militancy in Pakistan: Rebottling the Genie

    DTIC Science & Technology

    2013-03-01

    of Command, Leadership and Management 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS(ES) U.S...Martin Department of Command, Leadership and Management Project Adviser This manuscript is submitted in partial fulfillment of the requirements of...dictatorship. “Governance is the exercise of power or authority– political, economic, administrative, or otherwise– to manage a country’s resources and

  16. Militancy in Pakistan: A Schizophrenic Problem

    DTIC Science & Technology

    2012-09-01

    and must protect the vulnerable Punjabi plain. Pakistan’s major population centers and much of its infrastructure are situated near the Indian...that Pashtun tribes have had a strong aversion to invading armies. With 75% of military personnel from the Punjabi region, the ethnic disparity... Punjabi dominated social strata. Initial Pashtun incorporation into the state’s jurisdiction began when the British Raj formally recognized the two

  17. Militant morality: civil disobedience and bioethics.

    PubMed

    Cohen, C

    1989-01-01

    Seven essays in this issue of the Hastings Center Report defend civil disobedience as a legitimate form of protest against terrible injustices: legalized abortion (G. Leber); abridgement of women's reproductive rights (S. Davis); government policy toward persons with AIDS (H. Spiers and A. Novick); abuse of the rights of animals (S. Siegel, C. Jackson, and P. Singer). An eighth essay, by B. Nathanson, examines the motivations of Operation Rescue, an organization that uses civil disobedience to protest legalized abortion. Cohen explores the problems that these authors and others encounter in trying to justify deliberately breaking the law in public conscientious protest. He examines three forms of protest -- direct civil disobedience, indirect civil disobedience, and direct action -- and three justifications -- higher-law, utilitarian, and only possible means. Cohen concludes that, in a democracy, objective justification of civil disobedience is very difficult.

  18. How Drone Strikes and a Fake Vaccination Program Have Inhibited Polio Eradication in Pakistan: An Analysis of National Level Data.

    PubMed

    Kennedy, Jonathan

    2017-10-01

    This article investigates whether the United States' counterinsurgency operations have inhibited polio eradication efforts in northwestern Pakistan, the world's last major reservoir of polio. Anecdotal evidence suggests that militants disrupt polio vaccination programs because of suspicions that campaigns are a cover for gathering intelligence on Central Intelligence Agency (CIA) drone targets. This paper analyzes national-level quantitative data to test this argument. Between 2004 and 2012, the number of polio cases in Pakistan closely mirrored the number of drone strikes. But from 2013 onward, polio cases increased while drone strikes fell. This can be explained by the CIA's use of a fake immunization campaign in a failed attempt to obtain the DNA of Osama bin Laden's relatives prior to his assassination in 2011. This seemingly vindicated militants' suspicions that vaccination programs were a cover for espionage. Militants consequently intensified their disruption of immunization campaigns, resulting in an increase in polio cases in Pakistan, as well as in Afghanistan, Syria, and Iraq. For politicians and military planners, drones are attractive because they are said to harm fewer civilians than conventional methods of warfare. However, this paper demonstrates that drone strikes had negative effects on the well-being of civilians in Pakistan and further afield because they undermined global efforts to eradicate polio.

  19. Socio-Educational Development of Pre-School Children in Eastern Cape: Factors Militating against Fathers' Readiness to Participate

    ERIC Educational Resources Information Center

    Salami, Ishola Akindele; Okeke, Chinedu

    2017-01-01

    Past studies on South African fathers' less or non-involvement in their children's development have either approached it qualitatively, with rural dwellers that are less educated than participants, or those that were quantitatively limited in terms of their focus and methodology. There is, therefore, a dearth of quantitative data on factors…

  20. A Critical Performance Pedagogy that Matters

    ERIC Educational Resources Information Center

    Denzin, Norman K.

    2009-01-01

    This paper outlines a critical performance pedagogy relevant to a postmodern democracy in a globalised post 9/11/01 world. A militant utopianism which challenges a politically conservative postpositivism is discussed. (Contains 9 notes.)

  1. Women Teacher Militancy in the Workplace 1910-1922.

    ERIC Educational Resources Information Center

    Thomas, William B.; Moran, Kevin J.

    1991-01-01

    Describes the political struggles of the Teacher's Educational League in Buffalo, New York, and its founder, Mary A. O'Conner. Discusses the issues and problems women teachers encountered in attempts to reform teacher administrator relations. Traces the league's challenge to the Board of Education and the state of New York; explains that many of…

  2. Why Do Militant Groups Experience Intra-organizational Conflict

    DTIC Science & Technology

    2016-12-01

    1 (February 2012): 94– 117. 27 divided leadership style and a united leadership style , when stable, can each provide benefits to the organization...advantages, a divided leadership strategy might have some as well. It might provide a “big tent” organization style allowing for a more diverse...conflict when they experience a loss of unified leadership , when they attempt to govern territory, when they obtain legal recognition from the state

  3. Why Are There Creationists?

    ERIC Educational Resources Information Center

    Moore, John A.

    1983-01-01

    Discusses why there are creationists, fundamentalists, and evolutionists. Topics addressed include: modern, primitive and creationist thought; myths; appeal of occult; experiments in naturalistic thought; early evolution of American fundamentalism; militant fundamentalism; fundamentalist activities; Islamic fundamentalism; and others. Suggestions…

  4. Myths, Money, and Catholic Schools: When the Apple Hit the Teacher's Toupee, and Other Stories

    ERIC Educational Resources Information Center

    Rivers, Caryl

    1972-01-01

    Author contrasts her own experience in Catholic schools with the progressive Fitton School in Boston, and compares the old-style lay teacher" with the new breed of militants, personified by the head of the Catholic Teachers Federation. (SP)

  5. The Changing Role of Women in the Armed Forces

    ERIC Educational Resources Information Center

    Goldman, Nancy

    1973-01-01

    Although there is ample reason to expect a gradual increase in numbers and a slow but steady expansion of assignment, there is little reason to believe that the all-volunteer army will be recruiting the most militant'' younger women. (Author)

  6. A Tale of Two Regimes: Instrumentality and Commons Access

    ERIC Educational Resources Information Center

    Toly, Noah J.

    2005-01-01

    Technical developments have profound social and environmental impacts. Both are observed in the implications of regimes of instrumentality for commons access regimes. Establishing social, material, ecological, intellectual, and moral infrastructures, technologies are partly constitutive of commons access and may militate against governance…

  7. Tuskegee Institute in the 1920's

    ERIC Educational Resources Information Center

    Marable, Manning

    1977-01-01

    During the time of Marcus Garvey, the Harlem Renaissance and Southern black labor militancy, Tuskegee perpetuated a conservative social philosophy. This contradictory legacy set the stage for a confrontation between the black middle class of Tuskegee and a white racist society. (Author/GC)

  8. An Annotated Bibliography of Latin American Military Journals.

    DTIC Science & Technology

    1965-12-01

    CABALLERIA Y UNIDADES BLINDADAS) REVISTA DE INFANTERIA REVISTA DE INGENIERIA MILITÄR (Organo de la Academia Politecnica Militär) REVISTA DEL...Appendix--continued ■84- PERU BOLETIN DEL MINISTERIO DE GUERRA Y MARINA (Continued as MEMORIAL DEL EJERCITO) INFANTERIA INGENIERIA REVISTA DEL

  9. Parameters of Institutional Change: Chicano Experience in Education.

    ERIC Educational Resources Information Center

    Santana, Ray; And Others

    During the 1960's, the Chicano movement directed considerable attention, energy, and resources toward educational change. The predominant mood was optimism and anticipation of major institutional change; the predominant tactic used was militant confrontation. Countless confrontations occurred and numerous plans and strategies for educational…

  10. A Special Issue on Black Women.

    ERIC Educational Resources Information Center

    Murray, Saundra Rice, Ed.; Scott, Patricia Bell, Ed.

    1982-01-01

    In six articles presents research reflective of the diversity and commonalities of the Black female experience. Deals with educational, career, and psychological issues surrounding Black adolescents, working and professional women, college students, and employed mothers. Discusses militancy, fear of success, coping, nontraditional careers, and…

  11. Somalia

    DTIC Science & Technology

    2013-04-01

    Full event data is available online . 2 fied assault on Al Shabaab positions outside Mogadishu, the group was already engaging in sporadic...uting to militants’ further radicalisation . In Somalia’s north -east, Al Shabaab militants have been reportedly operat- ing and establishing bases in

  12. Constructing Learning: Adversarial and Collaborative Working in the British Construction Industry

    ERIC Educational Resources Information Center

    Bishop, Dan; Felstead, Alan; Fuller, Alison; Jewson, Nick; Unwin, Lorna; Kakavelakis, Konstantinos

    2009-01-01

    This paper examines two competing systems of work organisation in the British construction industry and their consequences for learning. Under the traditional "adversarial" system, conflict, hostility and litigation between contractors are commonplace. Such a climate actively militates against collective learning and knowledge sharing between…

  13. Social Science Data Archives and Libraries: A View to the Future.

    ERIC Educational Resources Information Center

    Clark, Barton M.

    1982-01-01

    Discusses factors militating against integration of social science data archives and libraries in near future, noting usage of materials, access requisite skills of librarians, economic stability of archives, existing structures which manage social science data archives. Role of librarians, data access tools, and cataloging of machine-readable…

  14. Attitudes of Ontario Secondary School Teachers toward Aspects of Professional Negotiations and Sanctions.

    ERIC Educational Resources Information Center

    Selinger, Alphonse D.

    1980-01-01

    Ontario secondary teachers were more favorable in 1977 than 1974 towards collective bargaining but showed significantly less support for sanctions, especially striking. Still, if their interests were seriously threatened, they would strike. Teacher sex and length of Ontario residence were significant predictors of militancy. (Author/SB)

  15. Toward the Prediction of Events in Teachers' Contract Negotiations.

    ERIC Educational Resources Information Center

    Fris, Joe

    This study attempted to formulate a method of assessing teachers' affective states that can predict the course of teacher contract negotiations. Researchers attempted to analyze and quantify teachers' feelings of professional role deprivation (PRD) and attitudinal militancy and to assess the relationship between the two. Professional role…

  16. What Will It Take To Ensure Implementation? A Content Literacy Dilemma.

    ERIC Educational Resources Information Center

    Rafferty, Cathleen D.

    A study attempted to determine a variety of facilitating and militating elements that influence Content Area Literacy/Learning Teaching Strategies (CAL/LTS) implementation. It investigated the impact of various contextual or ecological features embedded within the student teaching experience on student teachers' ability to implement various…

  17. Teacher-Board Relations in Virginia: A Case of Perceptual Discontinuity.

    ERIC Educational Resources Information Center

    Carlton, Patrick W.; Johnson, Richard T.

    1981-01-01

    Reports the results of a survey of teachers and school board members in Virginia on their opinions concerning collective bargaining and teacher involvement in militant activities or in political activism to achieve economic goals. The data revealed almost complete disagreement between the two groups. (Author/WD)

  18. Transnational Links of Afghan Madrasas: Implications for the Reform of Religious Education

    ERIC Educational Resources Information Center

    Borchgrevink, Kaja

    2013-01-01

    Described as "terrorist factories", the South Asian madrasas have become the subject of great controversy since September 11, 2001. In Afghanistan, people commonly blame Pakistani madrasas for recruiting Afghan youth into militant groups. In response, the Afghan government has initiated a comprehensive reform of the Islamic education…

  19. Islamic Education and Civil Society: Reflections on the "Pesantren" Tradition in Contemporary Indonesia

    ERIC Educational Resources Information Center

    Pohl, Florian

    2006-01-01

    Since the events of September 11, 2001, Islamic institutions of learning have received much attention. Indonesia's "pesantren" (Islamic boarding schools) have been increasingly described as fostering radicalism and violent militancy, particularly in light of purported links between a few of the country's "pesantren" and some of…

  20. University Industry Collaboration and Graduates' Unemployment in Ondo State, Nigeria

    ERIC Educational Resources Information Center

    Adepoju, O. O.; Adedeji, A. O

    2015-01-01

    Research evidence shows that university industry collaboration presents a wide range of benefits to industries, higher institutions, and to the development of a nation. This study investigated the existence of university industry collaboration, the factors militating against the collaboration, and the extent to which university industry…

  1. It's Not about "Us": "Express Newark" Prioritizing the Public Good

    ERIC Educational Resources Information Center

    Davson, Victor; Englot, Anne Schaper; Fischzang, Chantal; Fleming, Tamara; Kline, Nick

    2018-01-01

    Publically engaged scholarship demands new ways of working within and outside of the academy. Systems within the university reward faculty for individual achievements. This approach militates against working on collaborative projects because of the difficulty of explaining and quantifying one's contribution. The culture of academia further…

  2. Pakistan-U.S. Relations

    DTIC Science & Technology

    2009-02-06

    Peshawar. Days later, an Iranian diplomat in Peshawar was kidnaped by suspected Sunni militants, and a Japanese journalist and his Afghan colleague were...center, a café frequented by foreigners, a cinema house, and two hospitals. Six American citizens were among the 26 foreigners reported dead. Indian

  3. Understanding Militant Teacher Union Members' Activities in Secondary Schools

    ERIC Educational Resources Information Center

    Mahlangu, Vimbi P.

    2013-01-01

    This article investigates the activities of teacher unions in some Gauteng secondary schools in South Africa. The methods used in collecting data were questionnaires, interviews and a literature study of appropriate educational and labour law journals, books and newspapers. An interpretive paradigm was used in analysing the data. In this article,…

  4. Islamic Militancy in Bangladeshi Newspaper Editorials: A Discourse Analysis

    ERIC Educational Resources Information Center

    Khan, Mahmud Hasan; Govindasamy, Subramaniam

    2011-01-01

    The representation of a religio-political identity by the "civil society" of a country is a complex act intersecting multiple spheres such as the sociocultural, economic, and particularly partisan understanding of religion, politics, and culture dividing the society (and media houses) who inflect, invent, and articulate novel identity…

  5. Ayman Al-Zawahiri: The Ideologue of Modern Islamic Militancy

    DTIC Science & Technology

    2004-03-01

    and actual combat experience for EIJ members. 8 . . . Ayman Al-Zawahiri Two such Egyptian-Afghan mujahideen and EIJ members, Naeem Nabeel Abdul...Gives Life Meaning, (New York: PublicAffairs Press, 2002), 45-46. 18. Nabeel Sharaf-al-Din, Bin Laden, The Taliban and the Fundamentalist Movement...Radical Islam and the Future of America (Dulles, Virginia: Brasseys, 2002), 59. 34. Nabeel Sharaf-al-Din, “Bin Laden, The Taliban and the

  6. Some Recurrent Disagreements about Social Change Which Affect Action Research Projects.

    ERIC Educational Resources Information Center

    Hofstetter, Heather N.; Hofstetter, Merlin I.

    This paper describes the beliefs and values of a pluralistic approach to social change and of four competing approaches: social Darwinism, functionalism, militancy, and conflict theory. Stressing the alienation and dogmatism of the competing approaches, the authors relate each approach to its operation in community action projects. Social…

  7. Afro-American Identity: The Jamaican Nexus.

    ERIC Educational Resources Information Center

    Gullick, Charles J. M. R.

    1983-01-01

    Describes the ethnic history and the economic development of Jamaica from its beginnings as a Spanish colony through British rule to post-World War II independence. Rastafarianism, an extremist Black nationalist movement, arose after independence. Its militancy is due to an overwhelmingly Black majority population, with few countervailing ethnic…

  8. Enhancing the Student Experiment Experience: Visible Scientific Inquiry through a Virtual Chemistry Laboratory

    ERIC Educational Resources Information Center

    Donnelly, Dermot; O'Reilly, John; McGarr, Oliver

    2013-01-01

    Practical work is often noted as a core reason many students take on science in secondary schools (high schools). However, there are inherent difficulties associated with classroom practical work that militate against scientific inquiry, an approach espoused by many science educators. The use of interactive simulations to facilitate student…

  9. Impediments to Effective Utilisation of Information and Communication Technology Tools in Selected Universities in the North-Eastern Nigeria

    ERIC Educational Resources Information Center

    Momoh, Mustapha

    2010-01-01

    This study examined the impediments to effective use of Information and Communication Technology (ICT) tools in Nigerian universities. Series of research conducted on the factors militating against computerisation indicated that, there were impediments to effective utilisation of ICT tools in most developing countries. In the light of this, the…

  10. The Changing Dynamics of Health Care: Physician Perceptions of Technology in Medical Practices

    ERIC Educational Resources Information Center

    Hatton, Jerald D.

    2012-01-01

    Political, economic, and safety concerns have militated for the adoption of electronic health records (EHR) by physicians in the United States, but current rates of adoption have failed to achieve the expected levels. This qualitative phenomenological study of practicing physicians reveals obstacles to adoption. Maintaining the physicians'…

  11. Political Engineering in Africa.

    ERIC Educational Resources Information Center

    Mazrui, Ali A.

    1983-01-01

    Describes the political development of post-colonial Africa. Continuing tension has existed between single party and multi-party solutions to political organization and between mass movements and elitism. While Africans have been responive to socialist rhetoric, the primacy of ethnicity and the weak class structure have militated against genuine…

  12. Islamic Education and Indoctrination: The Case in Indonesia. Routledge Research in Education

    ERIC Educational Resources Information Center

    Tan, Charlene

    2011-01-01

    Islamic schools, especially "madrasahs", have been viewed as sites of indoctrination for Muslim students and militants. Some educators and parents in the United States have also regarded introductory courses on Islam in some public schools as indoctrinatory. But what do we mean by "indoctrination"? And is Islamic education…

  13. A Forecast of the Interaction Between Business and Society in the Next Five Years.

    ERIC Educational Resources Information Center

    Gordon, Theodore J.; And Others

    Projections about the interaction between business and society from 1971-75, made by a panel of 23 businessmen and students, are reported. Respondents each answered two questionnaires; the second questionnaire was based on results from the first, to make projections more precise. Respondents predicted that militant acts directed against business…

  14. Madrasas and Pakistan's Education Agenda: Western Media Misrepresentation and Policy Recommendations

    ERIC Educational Resources Information Center

    McClure, Kevin R.

    2009-01-01

    Evidence suggests that there is a link between certain madrasas in Pakistan and militant Islamic fundamentalism. However, this link has been inflated by Western media in an attempt to indict madrasas as the genesis of violent Islamic radicalism. The following study draws upon recent research and overlooked historical narratives, demonstrating that…

  15. Implication of Radicalisation for Nigerian Education: A Philosophical Analysis

    ERIC Educational Resources Information Center

    Nwafor, Naboth H. A.; Nwogu, Godpower A. I.

    2015-01-01

    The crises rocking the foundations of this world and threatening its existence have assumed a horrifying dimension. This situation is compounded by the increasing drift by young people into radicalized violent extremist militant groups. This paper attempts a conceptual analysis of the term radicalisation, the processes involved in it, its…

  16. The Changing Legal Climate for Marketing and Advertising in Europe.

    ERIC Educational Resources Information Center

    Dunn, S. Watson

    Although advertisers and marketers can expect stronger controls in all West European countries, especially by governments, they must be alert to country-by-country differences. Political moves to the left in any country will hasten controls. Consumerism is militant in some countries, practically dormat in others. Although self regulation is strong…

  17. Issues of Instructional Supervisory Practices in Primary Schools of Ebonyi State

    ERIC Educational Resources Information Center

    Onele, Adali A.; Aja-Okorie, Uzoma

    2016-01-01

    The study examines the issue of instructional supervision in primary schools of Onueke educational zone of Ebonyi state. The purpose of the study was to find out the problems militating against effective instructional supervision in the zone. Four research questions guided the study and descriptive survey research design was employed. The…

  18. Exercices de grammaire et discours rapporte (Grammar Exercises and Reported Discourse)

    ERIC Educational Resources Information Center

    Authier, Jacqueline; Meunier, Andre

    1977-01-01

    An analysis of exercises concerning indirect, direct and free discourse appearing in tests of the "premier cycle," from both pedagogical and linguistic points of view. The thesis is that a method giving primacy to manipulative exercises based on prefabricated sentences militates against discourse and communication. (Text is in French.) (AMH)

  19. Distance Education in Guyana. Report of a Project Identification Consultancy. Consultant Report 3.

    ERIC Educational Resources Information Center

    Commonwealth of Learning, Vancouver (British Columbia).

    Distance education is the only prospect of bringing further educational opportunities within the grasp of most adults in Guyana. Some factors that make distance education desirable, such as the infrastructure and present economic problems, militate against its provision. Many of the best educated personnel in all sectors have emigrated; the loss…

  20. Teachers Working for Change: Gender Equity and the Politics of Teacher Activism in South Korea

    ERIC Educational Resources Information Center

    Lee, Yoonmi

    2006-01-01

    This paper examines the controversies over the Women's Committee of the Korean Teachers Union (KTU) or "Chunkyojo"--in particular, the implementation of the quota policy which requires that 50% of the union's representative body be composed of women. Initially, this policy led to concerns that the KTU's militancy may be weakened.…

  1. Israel: Background and U.S. Relations

    DTIC Science & Technology

    2014-07-31

    59 End- Use Monitoring...conflict on July 6-7, 2014. Israel began a ground operation in Gaza on July 17 with the stated objective of destroying tunnels used by militants to...means of close-quarters combat (including the use of improvised explosive devices, or IEDs) have proven substantially lethal and damaging. According

  2. The Antwerp (Stair) Case: How a Modernist Architect Staged His Educational and Ideological Programme

    ERIC Educational Resources Information Center

    Couchez, Elke

    2017-01-01

    This paper looks at the educational project of Belgium's acclaimed socialist and modernist architect Renaat Braem (1910-2001). While Braem is foremost remembered as a militant opinion maker, his work as an educator and an artist has received little scrutiny. When Braem was appointed interim director at the Antwerp National Higher Institute for…

  3. A Primer on Developing Measures of Effectiveness

    DTIC Science & Technology

    2010-08-01

    does not tell us how to secure the general populace, so we have to continue our research. In The Quest for Viable Peace, Ben Lovelock reports that...Resolution, ed. Robert C. Orr (Washington, DC: The CSIS Press, 2004), 40. 17. Ibid., 42. 18. Ben Lovelock , “Securing a Viable Peace: Defeating Militant

  4. Extremist Media and the Rise of Terrorism: The Argentine Case.

    ERIC Educational Resources Information Center

    Day, J. Laurence

    In the 20 months that Isabel Peron served as the first female chief of state of a South American country, the mass media in Argentina underwent extreme stress. The Montoneros, a militant leftist organization, called for mass demonstrations against the orthodox Peronist people in their tabloid "La Causa Peronista." The tabloid's…

  5. Credits and Credibility: Educating Professionals for Cultural Sensitivity.

    ERIC Educational Resources Information Center

    Morgan, Elizabeth; Weigel, Van

    A four-part discussion on cultural sensitivity and good listening skills in development professionals is presented. It is noted that there is much in their educational regimen which militates against developing these habits of mind. It is hypothesized that much of this problem resides in the hidden cultural meanings of professionalism in general…

  6. Students' Roles in Maintaining Quality and in Enhancing Learning: Is There a Tension?

    ERIC Educational Resources Information Center

    Little, Brenda; Williams, Ruth

    2010-01-01

    This article is about student engagement and in particular the engagement of students in internal institutional quality assurance processes in the UK. It discusses the extent to which the introduction of more explicit internal and external quality assurance processes militate against the notion of the student as a part of a "cohesive learning…

  7. Education and Attitudes in Pakistan: Understanding Perceptions of Terrorism. Special Report 367

    ERIC Educational Resources Information Center

    Afzal, Madiha

    2015-01-01

    This report aims to understand the roots of an array of intolerant, biased, and--in some cases--radical attitudes in the Pakistani populace, including anti-Americanism, hatred of India and Hindus, intolerance of minorities, and some sympathy for militant groups. Underlying such attitudes are intolerance, prejudice, hate, and bigotry, along with a…

  8. Children and Religion

    ERIC Educational Resources Information Center

    Ogryzko, I. I.

    1971-01-01

    The nature of the Soviet system of atheistic indoctrination is elaborated as an organic part of the entire process of teaching and upbringing, taught in all grades, in all subjects, and in all extracurricular and extra-school work. It is based on scientific criticism of religion, deduction, interdisciplinary study, militant student participation…

  9. Repositioning Nigeria University Education for Economic Development through Entrepreneurship Education

    ERIC Educational Resources Information Center

    Adamu, L. E.

    2015-01-01

    Nigerians have always realized that education is the singular factor that brings about national development. The central goal of university education is to prepare one for productive employment. Such employment can be a paid one or a self-employed one. This paper examines the problem militating against university education, its implications for…

  10. A Filing System for Aerospace Medicine Reprints

    DTIC Science & Technology

    1987-04-03

    ORGANIZATION REPORT NUMBER(S) 5. MONITORING ORGANIZATION REPORT NUMBER(S) USAFSAM- TP -87-8 6a. NAME OF PERFORMING ORGAN!ZATION 6b. OFFICE SYMBOL 7a...17. Congdon , i.E. and McPherson, I.E. The care and feeding of your medical file. Milit. Med. 1984; 149:293-194. AEROSPACE MEDICINE - 1986 ABPM CONTENT

  11. Revolutionary Peacemaking: Using a Critical Pedagogy Approach for Peacemaking with "Terrorists"

    ERIC Educational Resources Information Center

    Best, Steven; McLaren, Peter; Nocella, Anthony J., II

    2007-01-01

    In this article, the authors note that peacemaking is based on working and dialoguing with radicals and militants, a point which many academics, government, and law enforcement agencies so easily forget. They aim to show that revolutionaries often have legitimate goals, needs, and demands which, if not addressed and respected, can prompt them to…

  12. Promoting Diversity in Creative Art Education: The Case of Fine Art at Goldsmiths, University of London

    ERIC Educational Resources Information Center

    Hayton, Annette Ruth; Haste, Polly; Jones, Alison

    2015-01-01

    Students studying art at university in the United Kingdom tend to be female, from higher social classes and from majority ethnic groups. This paper considers some of the complex and deeply-rooted social and economic factors that militate against wider participation in the arts and describes how we started to tackle under-representation at…

  13. Woman Suffrage and the 19th Amendment. Teaching with Documents.

    ERIC Educational Resources Information Center

    National Archives and Records Administration, Washington, DC.

    Beginning in the mid-19th century, several generations of woman suffrage supporters lectured, wrote, marched, lobbied, and practiced civil disobedience to achieve what many people considered a radical change in the U.S. Constitution. Militant suffragists used tactics such as parades, silent vigils, and hunger strikes. In 1870 the 15th amendment to…

  14. Student Participation in University Decision Making.

    ERIC Educational Resources Information Center

    Morris, Arval A.

    The causes of student rebellion against established social and educational systems are rooted in many forces that impinge upon their lives, 3 of which are rapid social change, affluence, and the fear of technological death. The firm conviction of "new left" activists --the third generation of radical, militant students-- is that they must do…

  15. The Specter of Sunni Military Mobilization in Lebanon

    DTIC Science & Technology

    2013-11-01

    stabilization  Future national security environment and forces  European security issues, especially the Mediterranean littoral  West Africa...5  More space for militant narratives .......................................................... 8  The Syrian war comes...their political dominance  Sunni officials and elites attack the legitimacy of state institu- tions, particularly the Lebanese Army  The Future

  16. Islamist Extremism in Bangladesh

    DTIC Science & Technology

    2007-01-31

    political stability may create additional space within which Islamist militants may be increasingly free to operate. Such a development may have destabilizing implications for Bangladesh, South Asia, and the Islamic world. They also have the potential to undermine U.S. interests. See CRS Report RL33646, Bangladesh: Background and U.S. Relations, by Bruce Vaughn, for additional

  17. Ethnic Conflict and Sustainable Development in Nigeria: The Role of Peace Education

    ERIC Educational Resources Information Center

    Alonge, Rufus A.; Okunade, Helen F.

    2014-01-01

    The issue of ethnic conflict in Nigeria has become a burning national issue with its attendant problems. Its current predominance is reflected in the reports of various activities of ethnic militant in the country coupled with the high rising terrorism activities in the northern part of the country from which the traces of ethnicity problem cannot…

  18. Security Challenges in the Gulf of Guinea Sub-Region: Strategy for Nigeria

    DTIC Science & Technology

    2008-06-01

    Gas Fisheries Defense of Shipping Data Sea Power Functioning Ecosystem Nation-States Pollution & Misuse Criminal Activities Poaching ...region, these increased activities have created challenging security issues including increased piracy, poaching , terrorism, militant youth activities... impact its economic, social and political development. Also, the GoG’s vast sea area presents great challenges to the Nigerian nation and the

  19. Strahlen-und kinetische Waffen: Neue Waffentechniken und Rüstungskontrolle

    NASA Astrophysics Data System (ADS)

    Neuneck, Götz

    Laserstrahlen, Mikrowellen oder elektromagnetische Beschleuniger lassen sich nicht nur für zivile, sondern für militärische Zwecke einsetzen. Die Aufgabe einer vorbeugenden Rüstungskontrolle wäre es, diese wie andere künftige Waffentechnologien auf ihren destabilisierenden Charakter hin zu untersuchen und ihre Stationierung zu beschränken oder zu verhindern.

  20. Women and Violence: A Study of Women's Empowerment and Its Challenges in Jammu and Kashmir

    ERIC Educational Resources Information Center

    Gul, Showkeen Bilal Ahmad

    2015-01-01

    The focus of this paper is to highlight the violence against women's in Jammu and Kashmir. In Jammu and Kashmir Woman are the most vulnerable and worst hit section of the society especially under situations of violence caused by militancy and armed conflict. They don't only suffer from intense humiliation and harassment but also undergo traumatic…

  1. Defending Left Pedagogy: U.S. Communist Schools Fight Back against the SACB (Subversive Activities Control Board)...and Lose (1953-1957)

    ERIC Educational Resources Information Center

    Gettleman, Marvin E.

    2008-01-01

    During the 1940s and 1950s the U.S. Communist Party upgraded and broadened its adult education schools, abandoning or ideologically modifying the militant pedagogical centres that had sprung up during the 1920s and 1930s in many American cities. In New York the transformation was complicated as two Party schools (the Workers School and the School…

  2. Sixties Protest Music: The Key to Understanding the Counter Culture.

    ERIC Educational Resources Information Center

    Harrison, Benjamin T.

    During the 1960s, protest music was expressed primarily through the folk tradition; it was the most important medium of the counter culture. The folk music tradition of the 1960s found its roots in the music of Woody Guthrie and Pete Seeger. In their music, commercial success and professional standards were militantly opposed. Folk music raised…

  3. The Shock of the Old--The Militant Church and Education.

    ERIC Educational Resources Information Center

    Hunter, Roger

    Accelerated Christian Education (ACE) schools, which provide an alternative to state-supported and other church schools, began in the United States, but their growth in Australia has been rapid. In 1977, there was only one ACE school in Australia, but by 1982 there were 10. The schools, which are committed to Christian fundamentalism, are run by…

  4. Revisiting non-Gaussianity from non-attractor inflation models

    NASA Astrophysics Data System (ADS)

    Cai, Yi-Fu; Chen, Xingang; Namjoo, Mohammad Hossein; Sasaki, Misao; Wang, Dong-Gang; Wang, Ziwei

    2018-05-01

    Non-attractor inflation is known as the only single field inflationary scenario that can violate non-Gaussianity consistency relation with the Bunch-Davies vacuum state and generate large local non-Gaussianity. However, it is also known that the non-attractor inflation by itself is incomplete and should be followed by a phase of slow-roll attractor. Moreover, there is a transition process between these two phases. In the past literature, this transition was approximated as instant and the evolution of non-Gaussianity in this phase was not fully studied. In this paper, we follow the detailed evolution of the non-Gaussianity through the transition phase into the slow-roll attractor phase, considering different types of transition. We find that the transition process has important effect on the size of the local non-Gaussianity. We first compute the net contribution of the non-Gaussianities at the end of inflation in canonical non-attractor models. If the curvature perturbations keep evolving during the transition—such as in the case of smooth transition or some sharp transition scenarios—the Script O(1) local non-Gaussianity generated in the non-attractor phase can be completely erased by the subsequent evolution, although the consistency relation remains violated. In extremal cases of sharp transition where the super-horizon modes freeze immediately right after the end of the non-attractor phase, the original non-attractor result can be recovered. We also study models with non-canonical kinetic terms, and find that the transition can typically contribute a suppression factor in the squeezed bispectrum, but the final local non-Gaussianity can still be made parametrically large.

  5. Making Education Relevant to Vital Social Change: The Higher Learning and Our National Destiny.

    ERIC Educational Resources Information Center

    Cheek, James E.

    It now seems clear that the decade of the seventies will be a new era of vital social change during which the US will be forced to come to grips with the issues of war, poverty, and racism. Today's student unrest already indicates that a new order is emerging. Moderates seek change through reform and militants seek it through revolution, but both…

  6. A Mature Maritime Strategy for Africa to Meet National Security Goals

    DTIC Science & Technology

    2011-06-17

    by corrupt governments, poverty, piracy, poaching in territorial waters, terrorist cells, militant youth activities, environmental violations, illegal...regions with maritime distress that are, or have the potential to impact vital U.S. national interests. Good national strategy that informs combatant and...environmental violations and many other debilitating maritime activities get conveyed ashore and directly impact the security and well-being of the

  7. Regional Mass Atrocity Prevention and Response Operations in a World of Overlapping Boundaries

    DTIC Science & Technology

    2012-05-17

    large scale, to include mass sexual violence, murder, genocide , displacement, or starvation.11 One might reasonably ask what the criteria are for...until well after the genocide was over. If America had intervened in Rwanda, it would likely have required a regional approach as militant groups used...civilians; these support her case. 37 Likewise, Marchak has pointed out that the Genocide

  8. Improving the United States’ Efforts in Countering Violent Extremist Organizations in Sub-Saharan Africa

    DTIC Science & Technology

    2016-04-04

    32 Al-Qa’ida in the Lands of the...Shabab Injuries 32 CHAPTER 8 Al-Qa’ida in the Lands of the Islamic Maghreb Al-Qa’ida in the Islamic Maghreb (AQIM) is a militant Islamist group...Since many of the Missions in Sub-Saharan Africa fall into the high or critical threat category for indigenous and transnational terrorism, the

  9. Using culture and psychology to counter the Taliban's violent narratives.

    PubMed

    Aggarwal, Neil Krishan

    2017-08-01

    Scholars, politicians, and policy-makers have increasingly pointed to the role of narratives in recruiting militants and justifying violence, highlighting the need for counter-narratives that promote peace. However, few have offered concrete guidelines on how to construct counter-narratives. This exploratory study uses prototype theory from social psychology to analyse Taliban narratives written in Arabic on the historical figure Maḥmūd of Ghaznī (971-1030), who is portrayed as a figure worthy of emulation. Key themes emerge from the Taliban's narratives: potential ingroup members are defined as Sunni Muslims who are committed to jihad; deviant Muslims must become Sunnis; non-Muslims must be converted and humiliated; and Taliban leaders should emulate Maḥmūd of Ghaznī's attributes. Contrasting the Taliban's narratives of Maḥmūd of Ghaznī with the historical record reveals themes that are culled empirically around which counter-narratives could be constructed.

  10. Genetic Contribution to Non-Squamous, Non-Small Cell Lung Cancer in Non-Smokers.

    PubMed

    Carr, Shamus R; Akerley, Wallace; Cannon-Albright, Lisa

    2018-04-04

    Lung carcinogenesis is strongly influenced by environmental and heritable factors. The genetic contribution to the different histologies is unknown. A population-based computerized genealogy resource linked to a statewide cancer registry of lung cancer cases (n=5408) was analyzed to evaluate the heritable contribution to lung cancer histology in smoking (n=1751) and non-smoking cases (n=818). Statistical methods were used to test for significant excess relatedness of lung cancer cases. Significant excess distant relatedness was observed for all lung cancer histology subgroups analyzed except the small cell lung cancer subset (p=0.213). When smoking and non-smoking histologic subsets of lung cancer were considered, excess relatedness was observed only in non-smoking NSCLC (n=653; p=0.026) and, particularly, in those non-smokers with non-squamous histology (n=561; p=0.036). Sixty one pedigrees were identified which demonstrated a significant excess risk of non-smoking, non-squamous lung cancer cases; and an excess of female cases was observed among the cases in these high-risk pedigrees. This analysis supports a genetic predisposition to lung cancer carcinogenesis in non-smoking, non-squamous NSCLC cases. Copyright © 2018 International Association for the Study of Lung Cancer. Published by Elsevier Inc. All rights reserved.

  11. Non-Gaussian, non-dynamical stochastic resonance

    NASA Astrophysics Data System (ADS)

    Szczepaniec, Krzysztof; Dybiec, Bartłomiej

    2013-11-01

    The classical model revealing stochastic resonance is a motion of an overdamped particle in a double-well fourth order potential when combined action of noise and external periodic driving results in amplifying of weak signals. Resonance behavior can also be observed in non-dynamical systems. The simplest example is a threshold triggered device. It consists of a periodic modulated input and noise. Every time an output crosses the threshold the signal is recorded. Such a digitally filtered signal is sensitive to the noise intensity. There exists the optimal value of the noise intensity resulting in the "most" periodic output. Here, we explore properties of the non-dynamical stochastic resonance in non-equilibrium situations, i.e. when the Gaussian noise is replaced by an α-stable noise. We demonstrate that non-equilibrium α-stable noises, depending on noise parameters, can either weaken or enhance the non-dynamical stochastic resonance.

  12. Joint Force Quarterly. Issue 45, 2d Quarter 2007

    DTIC Science & Technology

    2007-01-01

    liberal institutional explana- tion for alliances, Ota is really describing how the Japan Self - Defense Forces (JSDF) worked to share the risk and try...training, intelligence, and civil affairs) the armed forces of the Philippines in their operations against Abu Sayyaf, a self -declared militant...was preoccupied with domestic difficulties and disasters (largely self -inflicted) and the daunting demands of economic development. But with the

  13. Hamas and Israel: Conflicting Strategies of Group-Based Politics

    DTIC Science & Technology

    2008-12-01

    Brotherhood’s survival, as a result of the Egyptian government’s severe suppression of the Brethren. Even when the Brethren were released from Egyptian jails...founders of HAMAS developed a wing for militant action, thus breaking with the Palestinian, Egyptian , and Jordanian Muslim Brotherhood’s more...Eden supposed the Egyptian population would overthrow President Jamal abd al-Nasir. 13 Ironically, the attacks cemented Nasir’s popularity and

  14. Disrupting Terrorist Networks: An Analysis of the PKK Terrorist Organization

    DTIC Science & Technology

    2010-12-01

    conditions and the birth of the Turkish bourgeoisie . However, because Turkey’s economy was not able to finance this rapid improvement, the economy...indoctrinated militants, extorted the population, or taxed the sympathizers of the Kurdish diaspora in Europe.216 Unfortunately France , Germany...Germany shut down several websites and news agencies that supported the PKK.246 In 2007, France arrested 13 people who were suspected of PKK

  15. West Europe Report, No. 2204

    DTIC Science & Technology

    1983-09-15

    Markka 38 FRANCE CNPF, Government Clash Over Business Expense Figures "(Alain Barbanel; L’USINE NOUVELLE, 14 Jul 83) 39 ICELAND... FRANCE Leftwing Militants Oppose Economic, Foreign Policies (LE MONDE, 24 Jun 83) 72 NETHERLANDS Developments, Plans of Peace...either domestic or international) from taking place in such countries as France , England, Italy, Belgium and the FRG. In Portugal’s case there are two

  16. Looking at J.B.S. Haldane.

    PubMed

    Fara, Patricia

    2004-03-01

    J.B.S. Haldane's photographs reveal that this eminent geneticist was also a militant political agitator. Deeply engaged in left-wing British politics, Haldane eventually joined the Communist party, but found it increasingly difficult to reconcile his scientific beliefs with his Marxist commitments. During the controversy over Stalin's rejection of genetics in favour of Trofim Lysenko's agricultural reforms, Haldane's activities were critically interpreted from various different perspectives.

  17. Terrorism in South Asia

    DTIC Science & Technology

    2004-03-08

    with Bangladesh . Al Qaeda had reportedly recruited Burmese Muslims, known as the Rohingya , from refugee camps in southeastern Bangladesh to fight in...Dhaka, Bangladesh , June 19, 2003. 77 “ Bangladesh Calls Time Article on Militant Fictitious,” Associated Press, October 16, 2002. The Rohingya ...Solidarity Organization (RSO) is the largest organization representing the over 120,000 Rohingyas in Bangladesh .70 The number of Rohingyas varies depending

  18. CTC Sentinel. Volume 4, Issue 4, April 2011

    DTIC Science & Technology

    2011-04-01

    Online, April 28, 2010. 3 Personal interview, Khalid Khwaja, March 2010. 4 Personal interview, Usman Punjabi , Winter 2010. 5 Hamid Mir, “What Was...members’ identities. It eventually emerged that the Punjabi Taliban—jihadists who left Kashmir-focused militant groups and joined the TTP—were...involved in the kidnapping operation. Usman Punjabi , or Mohammad Omar as he identified himself when contacting the media, became the link between

  19. Influence: Maximizing Effects to Create Long-Term Stability

    DTIC Science & Technology

    2010-05-03

    Kilcullen, in a 2007 NOETIC brief, delineates popular perception into the emotive (“hearts”) component and the cognitive (“minds”) component. x...viii Zachary Abuza, “Balik Islam: The Return of Abu Sayyaf” (information paper, Carlisle, PA: U. S. Army War College, Strategic Studies Institute), 2...Strategic Studies Institute, 2005. Abuza, Zachary. Militant Islam in Southeast Asia: Crucible of Terror. Boulder, CO: Lynne Rienner Publishers, Inc

  20. Building a CATR Research Agenda, Proceedings of the Third Bi-Annual International Symposium of the Center for Asian Terrorism Research (CATR) Held in Colombo, Sri Lanka, 1-3 March 2006

    DTIC Science & Technology

    2006-11-01

    events such dance, drama, music , theatre, art and literature, and food festivals ; religious functions; cultural and social evenings; and...especially on the all-important tourism industry), and on day-to-day security. Fears continue to be expressed that the Nepalese state might collapse...of Eid- ul-Azha ( Muslim festival for animal sacrifice). An Islamic NGO run by militant leader, Asaadullah Al Galib, a Rajshahi University teacher

  1. Al Qaeda in Iraq: Demobilizing the Threat

    DTIC Science & Technology

    2005-12-01

    sources of manpower, finances , and material resources as well as an informational forum for disseminating the group’s message.9 Preexisting...education within their own country and finance the educational export of their form of Islam throughout the region as visible evidence of their...activists, finances , and military equipment. In a parallel effort, other Muslim states also exported their militant activists to Afghanistan to do their

  2. Sarcoidosis presenting as non-scarring non-scalp alopecia.

    PubMed

    Dan, Luke; Relic, John

    2016-08-01

    In this article we describe a 39-year-old man who presented with non-scarring non-scalp alopecia of his limbs as the initial presentation of sarcoidosis. Alopecia is a rare cutaneous manifestation of sarcoidosis. A literature review has found only one other example of sarcoidosis presenting as non-scarring non-scalp alopecia in an area other than the scalp in a patient who was otherwise asymptomatic. Several reported cases have described scarring alopecia of the scalp, which is the area of skin most commonly affected by sarcoidosis. There has been one documented case of sarcoidosis manifesting as total body non-scarring alopecia in a patient who had systemic symptoms of sarcoidosis. Other cases have presented rare cutaneous manifestations of sarcoidosis but in all these cases several other organ systems have been involved, and the patient has had systemic symptoms on presentation or the cutaneous presentation did not include non-scalp non-scarring alopecia. © 2015 The Australasian College of Dermatologists.

  3. Non-locality of non-Abelian anyons

    NASA Astrophysics Data System (ADS)

    Brennen, G. K.; Iblisdir, S.; Pachos, J. K.; Slingerland, J. K.

    2009-10-01

    Entangled states of quantum systems can give rise to measurement correlations of separated observers that cannot be described by local hidden variable theories. Usually, it is assumed that entanglement between particles is generated due to some distance-dependent interaction. Yet anyonic particles in two dimensions have a nontrivial interaction that is purely topological in nature. In other words, it does not depend on the distance between two particles, but rather on their exchange history. The information encoded in anyons is inherently non-local even in the single subsystem level making the treatment of anyons non-conventional. We describe a protocol to reveal the non-locality of anyons in terms of correlations in the outcomes of measurements in two separated regions. This gives a clear operational measure of non-locality for anyonic states and it opens up the possibility to test Bell inequalities in quantum Hall liquids or spin lattices.

  4. President Reagan’s commitment of Peacekeepers in Lebanon, 1983

    DTIC Science & Technology

    2015-05-21

    2008-10/25-years-later-we-came-peace. 5 Douglas Lute, Briefing to the Author, Brussels, September 2014. 5 such as Egypt , France and the United... God , published in 2013, examines how conflict in Lebanon allowed Iran to “aggregate under one roof a variety of militant Shi’a groups in Lebanon.”7...7 Matthew Levitt, Hezbollah, The Global Footprint of Lebanon’s Party of God (Washington

  5. Is the Department of State Accountability Review Board Process adequate

    DTIC Science & Technology

    2017-05-25

    of calculated terror campaigns, psychological conflict waged by nation or sub- group against nation, with an ever- broadening range of targets...the attack.11 However, the most politically significant attack occurred on November 4, when a large group of students and militants again stormed...the terrorist group Islamic Jihad carried out an attack against the US Embassy in Beirut, Lebanon. The bomb partially destroyed the U.S. Embassy and

  6. Kurdistan: The State That Cannot Be

    DTIC Science & Technology

    2016-05-26

    arm-kurdish-forces. 2 Graham E . Fuller, “The Fate of the Kurds,” Foreign Affairs, 72, no. 2 (Spring, 1993), pp. 108-121. 2 US has enabled...Sperl (London: Routledge, 1992), 10-11. 6 Vera Eccarius-Kelly, The Militant Kurds: A Dual Strategy for Freedom (Santa Barbara: Praeger, 2011), 178-181...fighting has caused the deaths of nearly 40,000 people, including civilians, Turkish 22 Vera Eccarius

  7. CTC Sentinel. Volume 1, Issue 10, September 2008. Seven Years After 9/11: More is Not Always Better

    DTIC Science & Technology

    2008-09-01

    al-Qahtani, seven Egyptians and a Jordanian. The first attacks attempted by a reconstituted al-Qa`ida in Yemen were the failed September 2006 dual...insight into the thinking of today’s Islamist militants. One such author is Adel Hammouda, an Egyptian social commentator, investigative journalist...Extremism from the June Defeat to the October Assassination). Hammouda was prompted to write his book in 1987 due to the failure of Egyptian intellectual

  8. United States and Western European Terrorist Groups - Current Status and Future Perspective.

    DTIC Science & Technology

    1982-06-07

    State, p. 173, 174 A respected commentator on terrorism, Walter Laqueur, Chairman of the International Research Council of the Center for Strategic ...American Nazi Party), the Black Panther Party, ( BPP ) and the American Indian Movement (AIM) were primarily involved in terrorist efforts in the late 60s...claiming to represent the JDL telephoned news organizations and said that the militant group was responsible for the fire. Subsequently leaders of the JDL

  9. Sub-Saharan Africa Report

    DTIC Science & Technology

    1987-04-07

    mother of three is no militant feminist . She trained at Stellenbosch University and qualified in social work and community develop- ment. At the same...20402. Correspondence pertaining to matters other than procurement may be addressed to Joint Publications Research Service, 10OO North Glebe Road...Accelerate SA’s Aerodynamics Research (SCIENTIAE, Mär 86) 94 Ceramic Developments at South Africa’s NIMR (SCIENTIAE, Mar 86) 99 /7310

  10. Iran: Politics, Gulf Security, and U.S. Policy

    DTIC Science & Technology

    2016-08-19

    nuclear weapon if it decided to do so. President Obama has asserted that the JCPOA has the potential to produce the added benefit of improving U.S... benefits , and can spend significant amounts of unbudgeted funds on arms, technology, and support to pro-Iranian movements. Society of Militant...international isolation, continues to back state intervention in the economy to benefit workers and lower classes. Appeared at some of the 2009 protests

  11. Consequences of Decapitation Policies

    DTIC Science & Technology

    2013-04-04

    must not execute the targeted killing. • The targeted killing must not be conducted with “ poison , expanding bullets, or other prohibited weapons” under...responded with a never-ending string of poisonings , bombings, kidnappings, and shootings. Chechen militants continue to replace lost leaders. Over the...34 Aaron Mannes, “Testing the Snake Head Strategy: Does Killing or Capturing Its Leaders Reduce a Terrorist Group’s Activity?” Journal of

  12. Work Domain Analysis of Australia’s Air Power System: Purpose-related Functions of Combat; Transport; and Intelligence, Surveillance, and Reconnaissance Subsystems

    DTIC Science & Technology

    2015-03-01

    of nature (e.g., flooding, drought, cyclone, earthquake, volcanic eruption , disease epidemic) or an act of man (e.g., riots, civil unrest, war...e.g., volcanic eruption ). To militate against these potential dangers, assets contributing to People Rescue (e.g., fixed-wing aircraft, rotary-wing...operating altitude of an aircraft to avoid strong winds or volcanic ash). UNCLASSIFIED DSTO-TR-3085 UNCLASSIFIED 69  “…rescue helicopters and

  13. Nuclear Weapons and Coercive Escalation in Regional Conflicts: Lessons from North Korea and Pakistan

    DTIC Science & Technology

    2014-11-01

    brinkmanship relies on apparently suicidal and self-destructive tactics. Pakistan is often described as a country that “negotiates with a gun to its own...On 13 December 2001, five militants armed with plastic explosives, suicide vests, assault rifles, and grenades infiltrated the secure perimeter...is true, it is possible that the temptation to engage in coercive escalation will become tempered over time as relatively new nuclear powers come to

  14. Bangladesh: Background and U.S. Relations

    DTIC Science & Technology

    2006-09-07

    influence through the political process and that this is creating space for militant activities inside the country. Some allege that the presence in the...well as its democratic process . Further, there is concern that should Bangladesh become a failed state, or a state controlled by Islamist...than 1 million Language : Bengali (official); English widely used Religion: Muslim 88.3%; Hindu 10.5% Life Expectancy at Birth: 62.46 (2006 est

  15. CTC Sentinel. Volume 3, Issue 4

    DTIC Science & Technology

    2010-04-01

    The attack targeted a popular German bakery located in the Koregaon Park area. The bakery is situated near a Hindu spiritual center (Osho...nitrate, RDX explosives and petroleum hydrocarbon oil.2 The bakery was likely targeted because it is located in a crowded area and more vulnerable...frequent the area. It is likely that the militants selected the bakery either due to heightened security measures at the respective spiritual and

  16. Transnational Insurgencies and the Escalation of Regional Conflict: Lessons for Iraq and Afghanistan

    DTIC Science & Technology

    2010-03-01

    and Turkey all aspire to a common homeland, or at least significant autonomy and the recognition of cultural rights. The Taliban is similarly...period of Soviet occupation. In decades past, militant groups such as the Palestine Liberation Organization (PLO), the Nicaraguan Contras, and the...to win a greater degree of autonomy from the Indian state.57 Although none of these ethnic rebels in the northeast have risen to the size and

  17. Touchstones for the Military Leadership Engaged in Asymmetric Warfare

    DTIC Science & Technology

    2004-03-19

    stricken conditions, to compensation for low esteem status, to religion and/or ideology driven needs to lastly, the vendetta driven need, wherein...Only about one fifth of the total interrogated had genuine religious fervor as the driving force and the ones with low esteem status and vendetta...FIGURE 1 REASONS FOR JOINING MILITANCY Some other findings revealed that for the low esteem category, the perceived luster of a ‘Robin

  18. The Origins and Strategic Objectives of the Al-Qaeda Organization in the Islamic Maghreb (AQIM)

    DTIC Science & Technology

    2009-12-01

    Group Islamic Army (the Armed Islamic Group) GSPC Salafist Group for Preaching and Combat GICM Groupe Islamique de Combat (Moroccan Islamic Combat...the Armed Islamic Group (GIA, Groupe Islamique Armé), emerged. The GIA was a group made up of former militants who always rejected the idea of...French acronym GICM: Groupe Islamique Combatant au Maroc), the Libyan Islamic Fighting Group LIFG . This analysis will determine the nature of the

  19. The United States’ Role in Combating Militant Islam in France

    DTIC Science & Technology

    2011-03-16

    United States Army DISTRIBUTION STATEMENT A : Approved for Public Release. Distribution is Unlimited. This SRP is submitted in partial...provision of law, no person shall be subject to any penalty for failing to comply with a collection of information if it does not display a currently...SPONSOR/MONITOR’S REPORT NUMBER(S) 12. DISTRIBUTION / AVAILABILITY STATEMENT Distribution A : Unlimited 13. SUPPLEMENTARY NOTES

  20. Experimental realization of non-Abelian non-adiabatic geometric gates.

    PubMed

    Abdumalikov, A A; Fink, J M; Juliusson, K; Pechal, M; Berger, S; Wallraff, A; Filipp, S

    2013-04-25

    The geometric aspects of quantum mechanics are emphasized most prominently by the concept of geometric phases, which are acquired whenever a quantum system evolves along a path in Hilbert space, that is, the space of quantum states of the system. The geometric phase is determined only by the shape of this path and is, in its simplest form, a real number. However, if the system has degenerate energy levels, then matrix-valued geometric state transformations, known as non-Abelian holonomies--the effect of which depends on the order of two consecutive paths--can be obtained. They are important, for example, for the creation of synthetic gauge fields in cold atomic gases or the description of non-Abelian anyon statistics. Moreover, there are proposals to exploit non-Abelian holonomic gates for the purposes of noise-resilient quantum computation. In contrast to Abelian geometric operations, non-Abelian ones have been observed only in nuclear quadrupole resonance experiments with a large number of spins, and without full characterization of the geometric process and its non-commutative nature. Here we realize non-Abelian non-adiabatic holonomic quantum operations on a single, superconducting, artificial three-level atom by applying a well-controlled, two-tone microwave drive. Using quantum process tomography, we determine fidelities of the resulting non-commuting gates that exceed 95 per cent. We show that two different quantum gates, originating from two distinct paths in Hilbert space, yield non-equivalent transformations when applied in different orders. This provides evidence for the non-Abelian character of the implemented holonomic quantum operations. In combination with a non-trivial two-quantum-bit gate, our method suggests a way to universal holonomic quantum computing.

  1. Fighting Status Inequalities: Non-domination vs Non-interference

    PubMed Central

    Nielsen, Morten Ebbe Juul

    2016-01-01

    Status inequalities seem to play a fairly big role in creating inequalities in health. This article assumes that there can be good reasons to fight status inequalities in order to reduce inequalities in health. It examines whether the neorepublican ideal of non-dominance does a better job as a theoretical foil for this as compared to a liberal notion of non-interference. The article concludes that there is a prima facie case for incorporating non-dominance into our thinking about public health, but that it needs to go hand in hand with a more traditional liberal ideal of non-interference. PMID:27551298

  2. Fighting Status Inequalities: Non-domination vs Non-interference.

    PubMed

    Nielsen, Morten Ebbe Juul; Landes, Xavier

    2016-07-01

    Status inequalities seem to play a fairly big role in creating inequalities in health. This article assumes that there can be good reasons to fight status inequalities in order to reduce inequalities in health. It examines whether the neorepublican ideal of non-dominance does a better job as a theoretical foil for this as compared to a liberal notion of non-interference. The article concludes that there is a prima facie case for incorporating non-dominance into our thinking about public health, but that it needs to go hand in hand with a more traditional liberal ideal of non-interference.

  3. A non-perturbative argument for the non-abelian Higgs mechanism

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    De Palma, G.; INFN, Sezione di Pisa, Pisa; Strocchi, F., E-mail: franco.strocchi@sns.it

    2013-09-15

    The evasion of massless Goldstone bosons by the non-abelian Higgs mechanism is proved by a non-perturbative argument in the local BRST gauge. -- Highlights: •The perturbative explanation of the Higgs mechanism (HM) is not under mathematical control. •We offer a non-perturbative proof of the absence of Goldstone bosons from the non-abelian HM. •Our non-perturbative proof in the BRST gauge avoids a mean field ansatz and expansion.

  4. Temporal Non-locality

    NASA Astrophysics Data System (ADS)

    Filk, Thomas

    2013-04-01

    In this article I investigate several possibilities to define the concept of "temporal non-locality" within the standard framework of quantum theory. In particular, I analyze the notions of "temporally non-local states", "temporally non-local events" and "temporally non-local observables". The idea of temporally non-local events is already inherent in the standard formalism of quantum mechanics, and Basil Hiley recently defined an operator in order to measure the degree of such a temporal non-locality. The concept of temporally non-local states enters as soon as "clock-representing states" are introduced in the context of special and general relativity. It is discussed in which way temporally non-local measurements may find an interesting application for experiments which test temporal versions of Bell inequalities.

  5. Yemen: Background and U.S. Relations

    DTIC Science & Technology

    2014-11-19

    been fighting t he central government, other northern Yemeni tribes, and militants associated with AI Qaeda in the Arabian Peninsula. The opponents...in self-defense. The AI Ahmar Family (pictured: Sheikh Sadiq AI Ahmar) The AI Ahmar family is t he leading clan in t he one of the largest tribal...family. Another prominent political figure in the clan is Hamid AI Ahmar, who sided with Yemeni protestors and against former president Saleh back in

  6. Pakistan: A Nation at War with Itself

    DTIC Science & Technology

    2010-12-01

    boundaries in India.13 As a recent Rand Corporation report argued, “the Use of militant groups, including the Taliban, has remained an important instrument...government at Dhaka in East Pakistan. Pakistan’s experiments with democracy have been marked by a “multi- layered trajectory of contrasts and...protect the city by destroying a large number of bridges on the canal that surrounded it. The Indian strategy of expanding the war beyond Kashmir was

  7. Weak and Failing States: Evolving Security Threats and U.S. Policy

    DTIC Science & Technology

    2007-11-15

    operate in both “ caves ” (i.e., failed states, where militant groups can exist CRS-6 11 Rabasa (2007), ibid. 12 U.S. Government Interagency Working Group...Support to Low-Income Countries Under Stress (Washington, DC: The World Bank, 2006); Chauvet and Collier, “Helping Hand? Aid to Failing States...Oxford University Working Paper (2006). 24 See Chauvet and Collier (2004), op. cit.; Francois Bourguignon, “Broadening Progress Toward the MDGs,” Speech

  8. Weak and Failing States: Evolving Security Threats and U.S. Policy

    DTIC Science & Technology

    2007-11-15

    operate in both “ caves ” (i.e., failed states, where militant groups can exist CRS-6 11 Rabasa (2007), ibid. 12 U.S. Government Interagency Working Group...Support to Low-Income Countries Under Stress (Washington, DC: The World Bank, 2006); Chauvet and Collier, “Helping Hand? Aid to Failing States,” Oxford...University Working Paper (2006). 24 See Chauvet and Collier (2004), op. cit.; Francois Bourguignon, “Broadening Progress Toward the MDGs,” Speech

  9. Weak and Failing States: Evolving Security Threats and U.S. Policy

    DTIC Science & Technology

    2008-08-28

    terrorists operate in both “ caves ” (i.e., failed states, where militant groups can exist with impunity) and “condos” (i.e., states that have the...of World Bank Support to Low-Income Countries Under Stress (Washington, DC: The World Bank, 2006); Chauvet and Collier, “Helping Hand? Aid to Failing...States,” Oxford University Working Paper (2006). 29 See Chauvet and Collier (2004), op. cit.; Francois Bourguignon, “Broadening Progress Toward the

  10. The Importance of Enduring Partnership Between the US and Pakistan in Combating Terrorism

    DTIC Science & Technology

    2008-01-01

    Hundreds of Pakistanis including armed forces members have so far been killed in these terrorist attacks. The most high profile personality that has so...far been killed in such attacks was Mrs Benazir Bhutto, Pakistan’s ex Prime Minister. Pakistan has so far provided following assistance to the US: a...Pakistan Army conducted operation in South Waziristan in 2004, during which 302 militants were killed while 656 were detained. Some 80% of these

  11. The Bundeswehr in the 21st Century - Between Prussia’s Glory and Design

    DTIC Science & Technology

    2011-05-19

    Berlin: 2010). 3 and later active member in the group of reformers, Carl von Clausewitz.3 This spirit found its expression in Clausewitz’s most notable...1801-1805 (Westport, Connecticut: Praeger Publishers, 1989), 101. 4 Carl von Clausewitz, On War, trans. and ed. Michael Howard and Peter Paret...für junge Offiziere (Academy for Young Officers) and the Militärische Gesellschaft (Military Society) both located in Berlin. Within three years

  12. Translations on Eastern Europe, Political, Sociological and Military Affairs, Number 1598.

    DTIC Science & Technology

    1978-10-17

    Approved for Public Release Distribution Unlimited 20000414 091 U. S. JOINT PUBLICATIONS RESEARCH SERVICE Reproduced From Best Available Copy i M ■1...MUNCA DE PARTID, Aug 78) 52 More Militancy Needed in Publications for Youth ( Alecu Popovici; ERA SOCIALISTA, 20 Aug 78) 58 Briefs...PUBLICATIONS FOR YOUTH Bucharest ERA SOCIALISTA in Romanian No 16, 20 Aug 78 pp 36, 37 /Article by Alecu Popovici_7 ZText/ Analyzing all the great literary

  13. Medical Research: A Bibliography of Walter Reed Army Medical Center Staff Publications, 1986-1989. Volume 1

    DTIC Science & Technology

    1990-01-01

    Wilson PD Jr: Fracture of the femoral component. Analysis of failure and long-term follow-up of rev-ision. Orthop Chin North Am 1988 Jul;19(3):637-47...DMED,DCI 88224857 Dysart SH, Savory CG, Callaghan JJ: Nonoperative treatment of a postoperative fracture around an uncemented porous-coated femoral...trochanter fractures of the hip without intertrochanteric extension: a case report. Milit Med 1988 Aug;153(8):421-3. DSURG 89015096 Lucente FE, Patow

  14. Thomas Jonathan ’Stonewall’ Jackson Fought by the Old Testament, Lived by the New

    DTIC Science & Technology

    1992-04-15

    the paternal Jacksons. Sometime in 1835, Laura went to live with their maternal relatives, the Neales.14 At seven years old, Jackson had become a...document may not be Maed for openi pub&hcdos unti it h- s been delrd by the appropriat militMs ftwvic@ o r~erment apncy. THOMAS JONATHAN "STONEWALL...SCHEDULE Distribution is unlimited. 4 PERFORMING ORGANIZATION REPORT NUMBER( S ) 5. MONITORING ORGANIZATION REPORT NUMBER( S ) 6a. NAME OF PERFORMING

  15. CTC Sentinel. Volume 6, Issue 2, February 2013

    DTIC Science & Technology

    2013-02-01

    Use of Militias to Maintain Stability in Abyan Province By Casey L. Coombs 7 Deciphering the Jihadist Presence in Syria: An Analysis of...and impose their authority in their communities . This poses particular challenges for Libya as i t moves through the transit ion process...IssUE 2 5 Yemen’s Use of Militias to Maintain Stability in Abyan Province By Casey L. Coombs in 2011, militants from al-Qa`ida in the Arabian

  16. The Concept of Comprehensive Security: A Distinctive Feature of a Shared Security Culture in Europe

    DTIC Science & Technology

    2007-12-01

    Sicherheitsbegriff, ed. Bundesakademie für Sicherheitspolitik (Hamburg: Mittler, 2001), 18. 92. Emil Kirchner and James Sperling , “The New Security Threats in...im 21. Jahrhundert - Keine allein militärische Aufgabe. Rede von Heidi Wegener, MdB, am 23.03.2006 im Marshall Center. www.marshallcenter.org/site...Wenger (Zürich: Forschungsstelle für Sicherheitspolitik, 2005), 11 217. Kurt R. Spillmann, " Von der bewaffneten Neutralität zur kooperativen

  17. Disrupting Emerging Networks: Analyzing and Evaluating Jamaat al-Muslimeen (JAM) and the Development of an Extremist Threat in the Caribbean

    DTIC Science & Technology

    2012-06-01

    New York’s JFK Airport that was to be executed by Muslim extremists with apparent ties to the Caribbean and Jamaat al-Muslimeen.4 This incident...is a known militant organization because of the 1990 coup attempt in Trinidad and the attempted attack on JFK airport in 2007. However, other Islamic...international terrorism with their alleged involvement in the planned attack on JFK airport in New York. The exposure of this plot brought forward the

  18. Abu Sayyaf

    DTIC Science & Technology

    2009-09-01

    Islamiyah (JI), a Southeast Asian militant Islamist group widely known and associated with the Bali nightclub bombing in 2002. 45 The new and... industry has been afflicted by natural disasters such as volcano eruptions as well as higher fuel costs making travel more expensive. In spite of these...occurrences, tourism receipts peaked in 1997 at close to $3 billion but by 2000 had dropped to less than $2 billion. Abu Sayyaf . . .9 Tourism is

  19. CTC Sentinel. Volume 6, Issue 4, April 2013

    DTIC Science & Technology

    2013-04-01

    July 2012, however, Hizb Allah operatives bombed a busload of Israeli tourists in Burgas, Bulgaria, killing five Israelis and a Bulgarian bus...Allah operative now serving time in a Cypriot prison for his role in a plot targeting Israeli tourists —to show how Hizb Allah has resurrected its...Military Academy, the Department of the Army, or any other agency of the U.s. Government . Lebanese Hizb Allah militants visit the grave of former

  20. An Examination of Overt Offensive Military Operations Outside of Combat Zones

    DTIC Science & Technology

    2006-12-01

    Robinson, John Arquilla, Jennifer Duncan and Edwin R. Micewski. The staff and research librarians of the Dudley Knox Library deserve special recognition...militants with the trainees and resources necessary for a terrorist attack like 9/11. John Arquilla writes that a protracted war is the wrong strategy...2004). 10 John Arquilla, “In the Fight Against Terrorism, The Long War is the Wrong War,” San Francisco Chronicle, 16 July 2006. 11 For a

  1. What Drives Pakistan’s Interest in Afghanistan?

    DTIC Science & Technology

    2011-05-19

    2010), 13. 172 Kamran Shafi, “Putting on a Brave Face and Standing Tall,” http://www.dawn.com/wps/wcm/connect/dawn-content-library/dawn/the-newspaper...columnists/ kamran -shafi- putting-on-a-brave-face-and-standing-tall-480 (accessed September 10, 2010). 59 include sanctuary, to militant...Shafi, Kamran . “Putting on a Brave Face and Standing Tall.” http://www.dawn.com/wps/wcm/connect/dawn-content-library/dawn/the- newspaper

  2. Non-Standard Orthography and Non-Standard Speech.

    ERIC Educational Resources Information Center

    Jaffe, Alexandra

    2000-01-01

    Provides a framework of key issues surrounding the non-standard orthographic representation of non-standard language varieties. The following topics are addressed: the selective nature of orthographic choice; relational an contrastive meaning of orthographic conventions; interplay of sameness and difference in use of orthography to make claims on…

  3. Non-stationary pre-envelope covariances of non-classically damped systems

    NASA Astrophysics Data System (ADS)

    Muscolino, G.

    1991-08-01

    A new formulation is given to evaluate the stationary and non-stationary response of linear non-classically damped systems subjected to multi-correlated non-separable Gaussian input processes. This formulation is based on a new and more suitable definition of the impulse response function matrix for such systems. It is shown that, when using this definition, the stochastic response of non-classically damped systems involves the evaluation of quantities similar to those of classically damped ones. Furthermore, considerations about non-stationary cross-covariances, spectral moments and pre-envelope cross-covariances are presented for a monocorrelated input process.

  4. Dangers Files Data: January-February 1979

    DTIC Science & Technology

    1979-05-01

    National Salvation. (NYT) (LAT); 01/08/79 *** 0086 *** 001 010 290 365 394 002 002 002 005 003 003 POLAND-USSR RELATIONS: The Polish leadership has...Militant Islamic clergymen in Iran express fears that leftist extremists may seize the leadership of +he struggle to oust the Shah. In recent weeks...disavowed +he religious leadership of the struggle. (LAT); 01/11/79 *** 0072 *** 003 010 630 000 000 001 002 008 008 008 008 IRAN INTERNAL DISSENSION

  5. JPRS Report West Europe

    DTIC Science & Technology

    1988-08-25

    with the municipalities about unchanged expenditures "and" POLITICAL taxes in 1989. But added to that, which many people seem to have forgotten when...signed the document. In addition to Osvaldo Castro, the current president of the county’s Municipal Assembly, Joaquim Carreira, long-time militant...about DM25 billion in these 3 years: North Rhine-Westphalia some DM7.1 billion and the municipalities at the Rhein and Ruhr rivers some DM2.7 billion

  6. Sexual Assault and Sexual Harassment in the U.S. Military: Highlights from the 2014 RAND Military Workplace Study

    DTIC Science & Technology

    2015-01-01

    assault, sexual harassment , and gender discrimination in the military. The resulting study, the RAND Military Workplace Study (RMWS), invited close to...members are highlighted in this brief. Sexual Assault and Sexual Harassment in the U.S. Military HigHligHts from tHe 2014 rAND militAry WorkplAce stuDy...significantly higher rates than men : 22 percent of women and 7 percent of men experienced sexual harassment in the past year. In addition, we estimate

  7. CTC Sentinel. Volume 5, Issue 11-12, November 2012

    DTIC Science & Technology

    2012-11-01

    Daho Ould Kablia on November 8, 2012, when he said that an intervention would have “very serious” consequences for “local populations” in the...reports claimed that they were killed when the militants detonated a roadside Improvised Explosive Device (IED) near a vehicle they were driving on a...group’s operating “base.” They were taken on a short tour of the location and shown a roomful of automatic weapons, grenade launchers, and explosives

  8. Three Lessons from Contemporary Challenges to Security

    DTIC Science & Technology

    2011-06-01

    advocates for gang members, but also mentors for young gang members. One of the great successes of the PCC has been to infiltrate or “colonize” the...to ensure that young gang members (and children of the convicts) who have the abil- ity and desire to enter public service can and do get the...challenge to the Spanish state and the global community. Therefore, that was the point at which these delinquents became militants. The purpose of

  9. Remotely Piloted Innovation: Terrorism, Drones and Supportive Technology

    DTIC Science & Technology

    2016-10-01

    IV Executive Summary In mid-August 2016, the Shiite militant group Hezbollah reportedly dropped two small bombs from what is believed to have been a...Michael Jenkins, The New Age of Terrorism (Santa Monica, CA: RAND Corporation, 2006), p. 119. 2 For example, see “Iraq Sees Worst Bombing Since...guns and bombs , Jackson and his colleagues also found that UASs did “not appear to have major advantages over other ways of carrying out operations

  10. New Terrorism In France

    DTIC Science & Technology

    2018-03-01

    transportation massacre at the hands of al-Qaeda backed militants. While France experienced social rioting in the summer of 2005, it still remained free from...did, I did of my own free will, without any influence by anyone who said to me one day ‘do this, do that.’ I did it all alone. I organized it all...157 Freeman, “Democracy,” 43. 158 The Washington Consensus refers to a set of broad free market economic

  11. Acquiring Information from Wider Scope to Improve Event Extraction

    DTIC Science & Technology

    2012-05-01

    solve all the problems might be hard or even impossible: Word sense disambiguation is already a hard NLP task, and normalizing different expressions...blindfolded woman seen being shot in the head by a hooded militant on a video obtained but not aired by the Arab television station Al-Jazeera. She...imbalance Why are we interested in unsupervised topic features? There is a problem that arises in the evaluation of almost all the tasks in NLP , concerning

  12. JPRS Report, Soviet Union, International Affairs.

    DTIC Science & Technology

    1987-09-14

    de estudios internationales (CEPEI), Lima, 1986, XXXVI+498 pp] [Text] The latest publication of the Peruvian Center for International Research is...one time a militant Indianist. The founder of APRA Aya de la Torre in his early works also preached the messianic role of the Indians, rejected...explosions in Lima, and dynamite attacks were made on one of the APRA district committees and on the ranch where the founder of the APRA Aya de la Torre had

  13. Operation Iraqi Freedom: Strategies, Approaches, Results, and Issues for Congress

    DTIC Science & Technology

    2008-09-22

    Tavernise, “Turkish Troops Enter Iraq in Pursuit of Kurdish Militants,” The New York Times, February 23, 2008; Lolita Baldor, “Gates: Turkey Raid Won’t...unofficial release of graphic photos of apparent detainee abuse at Abu Ghraib generated shock and horror among people inside and outside Iraq. Some...were mutilated and hung from a bridge. Photos of that grisly aftermath were rapidly CRS-66 232 The Iraq Governing Council (IGC) was a critical part of

  14. D.I.M.E.F.I.L.: A Wordwide Campaign for Life

    DTIC Science & Technology

    2007-05-01

    Joint Advanced Warfighting School in partial satisfaction of the requirements of a Master of Science Degree in Joint Campaign Planning and Strategy...of them. Al-Tamini stated his job was to “get a bomber to the best spot for an attack, where he can inflict the most damage.” Sometimes he...majority of militants were unmarried males 20-29 years old from families with both parents living and 6-10 siblings, and who completed secondary

  15. CTC Sentinel. Volume 6, Issue 3

    DTIC Science & Technology

    2013-03-01

    rac- ism. Locals reported that “light- skinned ” Arabs, Tu- aregs, and sub-Saharan Africans from Niger, Nigeria, Mali and other countries fought...Wadud), the amir of AQIM, to his lieutenants in the Sahara and to the Islamist militant group Ansar Eddine’s2 leader, Iyad ag Ghaly (also known as...2013. 2 Ansar Eddine, which means “Defenders of the Faith,” is a homegrown Islamist movement led by renowned Tu- areg rebel leader Iyad ag Ghaly

  16. Translations on North Korea. Number 534

    DTIC Science & Technology

    1977-06-13

    May 77)... Nature Remaking Work Needed To Occupy Food Grain Height ( Kim Il-song; ALGOK 1,000 MAN TON KOJIRUL CHOMNYONG HAGI WIHAN CHAYON KAEJO...meeting, Choe Yong -kun extended, on the occasion of the "week of support to the struggle of the Palestine people," warm congratu- lations and militant...people. Present at the meeting were Kim Kuk-hun, Yi Chong-mok, and other personages concerned, and working people in the city. Diplomatic envoys of

  17. An Analysis of the Doctrinal Changes that the Peruvian Army Implemented Fighting Counterinsurgency Operations Against the Sendero Luminoso Insurgency Since 2001

    DTIC Science & Technology

    2014-06-13

    there was a gap in controlling the SL insurgency by the Peruvian Army and the PNP in the RVH and RVAEM areas. Because of that, the SL branches...points of view will yield an accurate understanding of this organization. Their history begins with the formation of the basis of SL in the department...Lima. 2011 On 15 November, two allegedly senior SL militants, identified by security sources as Felipe Maiz and Giovanni Castillo, were detained by

  18. East Europe Report.

    DTIC Science & Technology

    1987-02-17

    existential conditions that had changed to the detriment of U.S. imperialism in order to stir up a "mood of national awaken- ing" by means of militant...historic mission of the working class. We see reflected here the profoundly humanist nature of Marxism-Leninism, its inherent sense of...realization of socialist and humanist ideals. But this does not mean that everything has already been done, that there is not much in daily life, in

  19. Deliberalization in Jordan: the Roles of Islamists and U.S.-EU Assistance in Stalled Democratization

    DTIC Science & Technology

    2010-06-01

    277, 281–293, 298–299. 12 World Bank and the International Finance Corporation, "Doing Business in the Arab World 2010: Comparing Regulations in 20...between harsh repression of the Islamist movement spearheaded by the Front Islamique du Salut (FIS) and the anti-civilian massacres committed by...militant Islamists of the Groupe Islamique Armé (GIA). Not only the brutality of the regime’s repression, but the way in which it fostered the “spirals

  20. 10 CFR 436.16 - Establishing non-fuel and non-water cost categories.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 3 2014-01-01 2014-01-01 false Establishing non-fuel and non-water cost categories. 436... PLANNING PROGRAMS Methodology and Procedures for Life Cycle Cost Analyses § 436.16 Establishing non-fuel and non-water cost categories. (a) The relevant non-fuel cost categories are— (1) Investment costs; (2...

  1. 10 CFR 436.16 - Establishing non-fuel and non-water cost categories.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 3 2013-01-01 2013-01-01 false Establishing non-fuel and non-water cost categories. 436... PLANNING PROGRAMS Methodology and Procedures for Life Cycle Cost Analyses § 436.16 Establishing non-fuel and non-water cost categories. (a) The relevant non-fuel cost categories are— (1) Investment costs; (2...

  2. Non-Polio Enterovirus

    MedlinePlus

    ... Controls Cancel Submit Search The CDC Non-Polio Enterovirus Note: Javascript is disabled or is not supported ... visit this page: About CDC.gov . Non-Polio Enterovirus Home About Non-Polio Enterovirus Symptoms Transmission Prevention & ...

  3. Electric-magnetic dualities in non-abelian and non-commutative gauge theories

    NASA Astrophysics Data System (ADS)

    Ho, Jun-Kai; Ma, Chen-Te

    2016-08-01

    Electric-magnetic dualities are equivalence between strong and weak coupling constants. A standard example is the exchange of electric and magnetic fields in an abelian gauge theory. We show three methods to perform electric-magnetic dualities in the case of the non-commutative U (1) gauge theory. The first method is to use covariant field strengths to be the electric and magnetic fields. We find an invariant form of an equation of motion after performing the electric-magnetic duality. The second method is to use the Seiberg-Witten map to rewrite the non-commutative U (1) gauge theory in terms of abelian field strength. The third method is to use the large Neveu Schwarz-Neveu Schwarz (NS-NS) background limit (non-commutativity parameter only has one degree of freedom) to consider the non-commutative U (1) gauge theory or D3-brane. In this limit, we introduce or dualize a new one-form gauge potential to get a D3-brane in a large Ramond-Ramond (R-R) background via field redefinition. We also use perturbation to study the equivalence between two D3-brane theories. Comparison of these methods in the non-commutative U (1) gauge theory gives different physical implications. The comparison reflects the differences between the non-abelian and non-commutative gauge theories in the electric-magnetic dualities. For a complete study, we also extend our studies to the simplest abelian and non-abelian p-form gauge theories, and a non-commutative theory with the non-abelian structure.

  4. From Prison to Citizenship: The Rhetoric of the Militant British Suffrage Movement.

    ERIC Educational Resources Information Center

    Kahl, Mary L.

    As nineteenth century British feminists found that they could no longer "suffer and be still," they forged alliances with those male political personalities sympathetic to their suffrage demands. Yet these political alliances proved to be of little value in the fight for voting rights, as measures designed to widen the franchise met with…

  5. Cimetidine attenuates vinorelbine-induced phlebitis in mice by militating E-selectin expression.

    PubMed

    Wang, Zhuo; Ma, Lijuan; Wang, Xuebin; Cai, Heping; Huang, Jin; Liu, Jiyong; Hu, Jinhong; Su, Dingfeng

    2014-08-01

    We investigated E-selectin expression in mice and rabbits with vinorelbine-induced phlebitis and the effect of cimetidine. To find the relationship between E-selectin expression and vinorelbine-induced phlebitis. Mouse and rabbit model of vinorelbine-induced phlebitis was established by intravenous infusion of vinorelbine. Pathological observation, molecular-biological determination of E-selectin and protein function of it was evaluated. Grossly, we observed swelling, edema and cord-like vessel changes in mice receiving vinorelbine but only mild edema in mice pretreated with cimetidine. Pathological scoring yielded a total score of 37 for vinorelbine-treated mice and 17 for mice pretreated with cimetidine (P < 0.05). ELISA revealed that rabbits treated with vinorelbine had markedly higher serum contents of E-selectin than normal saline (NS) controls (vinorelbine 1.534 ± 0.449 vs. NS 0.746 ± 0.170 ng/mL, P < 0.05), which was markedly attenuated by cimetidine (cimetidine 0.717 ± 0.468 vs. vinorelbine 1.534 ± 0.449 ng/mL, P < 0.05). Rose Bengal staining assays showed that vinorelbine markedly increased the adhesion rate of neutrophils for endothelial cells (vinorelbine 38.70 ± 8.34% vs. controls 8.93 ± 4.85%, P < 0.01), which, however, was significantly suppressed by cimetidine (9.93 ± 5.91%, P < 0.01 vs. vinorelbine). In E-selectin knockout mice, we found no apparent difference in tail swelling in mice receiving vinorelbine or cimetidine and vinorelbine. In conclusion, cimetidine attenuates vinorelbine-induced phlebitis in mice probably by suppressing increased expression of E-selectin.

  6. Balancing the Trinity: U.S. Approaches to Marginalizing Islamic Militancy in Pakistan

    DTIC Science & Technology

    2013-12-01

    an anti-Indian terrorist organization mostly composed of Pakistani Punjabis , Lashkar-e-Tayyiba is considered among the most “capable and high-profile...charitable wing known as Jamaat ud Dawa (JuD) (Office of the Coordinator for Counterterrorism, 2013). 3. Sectarian: Lashkar-i-Jhangvi As a Punjabi ...organization valuable access to the organizational infrastructure and funding in Pakistan’s Punjabi heartland (Fishman, 2013, p. 365). Through alliances

  7. Hamiltonian analysis of non-relativistic non-BPS Dp-brane

    NASA Astrophysics Data System (ADS)

    Klusoň, J.

    2017-07-01

    We perform Hamiltonian analysis of non-relativistic non-BPS Dp-brane. We find the constraint structure of this theory and determine corresponding equations of motion. We further discuss property of this theory at the tachyon vacuum.

  8. Non-autonomous Hénon--Heiles systems

    NASA Astrophysics Data System (ADS)

    Hone, Andrew N. W.

    1998-07-01

    Scaling similarity solutions of three integrable PDEs, namely the Sawada-Kotera, fifth order KdV and Kaup-Kupershmidt equations, are considered. It is shown that the resulting ODEs may be written as non-autonomous Hamiltonian equations, which are time-dependent generalizations of the well-known integrable Hénon-Heiles systems. The (time-dependent) Hamiltonians are given by logarithmic derivatives of the tau-functions (inherited from the original PDEs). The ODEs for the similarity solutions also have inherited Bäcklund transformations, which may be used to generate sequences of rational solutions as well as other special solutions related to the first Painlevé transcendent.

  9. Non-Lethal Weapons Program

    Science.gov Websites

    ), 26th Marine Expeditionary Unit (MEU), practice non-lethal control techniques during a non-lethal Skip to main content (Press Enter). Toggle navigation Non-Lethal Weapons Program Search Search JNLWP: Search Search JNLWP: Search Non-Lethal Weapons Program U.S. Department of Defense Non-Lethal

  10. Flurbiprofen : A non-selective cyclooxygenase (COX) inhibitor for treatment of non-infectious, non-necrotising anterior scleritis

    PubMed Central

    Agrawal, Rupesh; Lee, Cecilia; Gonzalez-Lopez, Julio J.; Khan, Sharmina; Rodrigues, Valeria; Pavesio, Carlos

    2016-01-01

    Objective To analyse the safety and efficacy of a non-selective cyclo-oxygenase (COX) inhibitor in the management of non-infectious, non-necrotising anterior scleritis. Methods Retrospective chart review of 126 patients with non-necrotising anterior scleritis treated with oral flurbiprofen (Froben®(Abbott Healthcare)) with ( group B, n=61) or without topical steroids (group A, n=65) was performed and time to remission was plotted. Results The observed incidence rate was 1.07 (95% CI: 0.57–1.99) per 1000 person-years with failure rate of 0.68 (95% CI: 0.22–2.12) per 1000 person-years in group A and 1.41 (95% CI: 0.67–2.96) per 1000 person-years in group B. The failure rate was 3.97(1.89–9.34) per 1000 person-years with hazard ratio of 10.01 ( 95% CI: 2.52–39.65; p<0.001) for patients with associated systemic disease. Conclusion To our best knowledge, this is the first and largest case series on the safety and efficacy of a non-selective COX inhibitor in the management of anterior scleritis. PMID:26308394

  11. CTC Sentinel. Volume 4, Issue 6, June 2011

    DTIC Science & Technology

    2011-06-01

    arrest and torture of teenagers who had written anti- regime graffiti sparked a wave of demonstrations in the southern Syrian city of Deraa. As a...more support, the easier it is for them to carry out activity. While its tactics are less popular, al-Qa`ida has managed to build a sizeable base of...militants managed to escape from the Wadi el-Natrun prison, where they had been detained.7 A couple of weeks later, on February 16, 2011, Chehab was

  12. The Haqqani Nexus and the Evolution of al-Qaida

    DTIC Science & Technology

    2011-07-14

    outgrowth  of  the  operational  “ glocalization ”  of  conflict  long  facilitated by the Haqqani network.47  The paradoxical challenge for Pakistan is that...unification of militant entities. For background on the term  “ glocalization ” see Roland Robertson, Globalization: Social Theory and Global Culture

  13. Nonstate Security Threats in Africa: Challenges for U.S. Engagement

    DTIC Science & Technology

    2010-12-01

    PRISM 2, no. 1 FeatuReS | 67 East Asia has led to a spike in elephant poach - ing. In June 2002, Singapore seized 6.2 metric tons of ivory (worth...country with no functioning cen- tral government since the 1980s.23 In addition to the impact on the lives and families of sailors who are taken...imports by 2015,25 and militant attacks impacting West African oil already affect the price of oil on global stock markets. The role played by

  14. Khattab (1969-2002)

    DTIC Science & Technology

    2015-02-01

    excellence. He was born in Saudi Arabia and took up jihad first in Afghanistan, then in Tajikistan and Dagestan, and finally in Chechnya , where he devoted...most of his political and militant energy and where he died. In the mid-1990s, he became the leader of the Arab Ansar in Chechnya , and he had his...Tajiks, Afghans and Uzbeks, who joined his group in Chechnya to fight against the Russians. He was keen to understand the culture of the places in

  15. Strategies of social and sexual control of Malaysian women in psychiatric institutional care.

    PubMed

    Crabtree, Sara Ashencaen

    2004-01-01

    An ethnographic study of female psychiatric patients was undertaken in East Malaysia. Findings indicate that these service users were subject to a number of sexist and oppressive practices that militate against their freedom of movement on the wards as well as their social interaction in the wider context of the hospital. Stereotypic notions of female sexuality and morality act as forms of moral containment and are interpreted in the hospital context as requiring heavy custodial care by the hospital authorities.

  16. Sub-Saharan Africa Report

    DTIC Science & Technology

    1987-03-24

    minister for planning and cooperation, Jose Brito, was referred to as "a militant in Africa’s development." Thus was stressed the " lucid realism and the...It is a dream place, with immense beaches and palm trees. Reminders of its past splendor are magnificent tiles of turquoise blue earthen- ware...fortunes through clever speculation. "Samora is dead, but there is a country to be built, a plan to be continued, a dream to made.an actuality," the pro

  17. [The physician in the Roman Army in the early period and at the height of the empire].

    PubMed

    Wilmanns, J C

    1995-01-01

    This article deals with the organization of health care in the Roman army, especially in the garrisons stationed in the more remote provinces of the Roman empire. A system of military healthcare was first created during the reign of Augustus. It consisted of various ranks of military physicians (milites medici) and assistants (capsarii and marsi) as well as military hospitals (valetudinaria). These played a major part in the spread of rational medicine over the less civilized parts of the Roman empire.

  18. Korean Affairs Report, KULLOJA, Number 7, July 1985

    DTIC Science & Technology

    1986-04-09

    happy events worthy of special mention in the history of our people’s struggle for the chuche revolutionary cause, our party has energetically appealed ...construction in the coming year." (Book "New Year’s Address," 1985, p 11) Loftily upholding the militant appeal of the party for glorifying the 40th...eventually become unable to observe the partywide principle and in the end, will fall to the ground as a useless snob . In order to make the

  19. From Sticks and Stones to Zeros and Ones: The Development of Computer Network Operations as an Element of Warfare. A Study of the Palestinian-Israeli Cyberconflict and What the United States Can Learn from the Interfada

    DTIC Science & Technology

    2005-09-01

    Israeli teens who sabotaged a website of Hezbollah, the militantly anti-Israel guerrilla movement in Lebanon, with a defacement which placed an Israeli...ftp with out a password. FUCK HIZZBALLA!!! Sincerely digibrain & haboshanik (we are the domain masters).” • Hackers of Israel Unite: Hackers of...other defacement. 2. b1n4ry c0d3 defaced only one site on December 3, 2000. This defacement was the only one to refer to the WFD as the “World’s Fuck

  20. 10 CFR 436.16 - Establishing non-fuel and non-water cost categories.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 3 2012-01-01 2012-01-01 false Establishing non-fuel and non-water cost categories. 436.16 Section 436.16 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION FEDERAL ENERGY MANAGEMENT AND PLANNING PROGRAMS Methodology and Procedures for Life Cycle Cost Analyses § 436.16 Establishing non-fuel and non-water cost categories. (a) The relevant...

  1. A New Algorithm Using the Non-Dominated Tree to Improve Non-Dominated Sorting.

    PubMed

    Gustavsson, Patrik; Syberfeldt, Anna

    2018-01-01

    Non-dominated sorting is a technique often used in evolutionary algorithms to determine the quality of solutions in a population. The most common algorithm is the Fast Non-dominated Sort (FNS). This algorithm, however, has the drawback that its performance deteriorates when the population size grows. The same drawback applies also to other non-dominating sorting algorithms such as the Efficient Non-dominated Sort with Binary Strategy (ENS-BS). An algorithm suggested to overcome this drawback is the Divide-and-Conquer Non-dominated Sort (DCNS) which works well on a limited number of objectives but deteriorates when the number of objectives grows. This article presents a new, more efficient algorithm called the Efficient Non-dominated Sort with Non-Dominated Tree (ENS-NDT). ENS-NDT is an extension of the ENS-BS algorithm and uses a novel Non-Dominated Tree (NDTree) to speed up the non-dominated sorting. ENS-NDT is able to handle large population sizes and a large number of objectives more efficiently than existing algorithms for non-dominated sorting. In the article, it is shown that with ENS-NDT the runtime of multi-objective optimization algorithms such as the Non-Dominated Sorting Genetic Algorithm II (NSGA-II) can be substantially reduced.

  2. Non-local bias in the halo bispectrum with primordial non-Gaussianity

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tellarini, Matteo; Ross, Ashley J.; Wands, David

    2015-07-01

    Primordial non-Gaussianity can lead to a scale-dependent bias in the density of collapsed halos relative to the underlying matter density. The galaxy power spectrum already provides constraints on local-type primordial non-Gaussianity complementary those from the cosmic microwave background (CMB), while the bispectrum contains additional shape information and has the potential to outperform CMB constraints in future. We develop the bias model for the halo density contrast in the presence of local-type primordial non-Gaussianity, deriving a bivariate expansion up to second order in terms of the local linear matter density contrast and the local gravitational potential in Lagrangian coordinates. Nonlinear evolutionmore » of the matter density introduces a non-local tidal term in the halo model. Furthermore, the presence of local-type non-Gaussianity in the Lagrangian frame leads to a novel non-local convective term in the Eulerian frame, that is proportional to the displacement field when going beyond the spherical collapse approximation. We use an extended Press-Schechter approach to evaluate the halo mass function and thus the halo bispectrum. We show that including these non-local terms in the halo bispectra can lead to corrections of up to 25% for some configurations, on large scales or at high redshift.« less

  3. Non-Market Valuation

    Treesearch

    Thomas P. Holmes

    2003-01-01

    In addition to commodities such as timber, forest ecosystems provide an array of goods and services that are not priced in markets but maintain, to a large degree, the characteristics of public goods (non-rivalry and non-excludability). Markets do not recognize scarcity of non-market resources and cannot be relied upon to allocate these resources to their highest and...

  4. 47 CFR 25.142 - Licensing provisions for the non-voice, non-geostationary mobile-satellite service.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 2 2011-10-01 2011-10-01 false Licensing provisions for the non-voice, non... Stations § 25.142 Licensing provisions for the non-voice, non-geostationary mobile-satellite service. (a... the non-voice, non-geostationary mobile-satellite service shall describe in detail the proposed non...

  5. 47 CFR 25.142 - Licensing provisions for the non-voice, non-geostationary Mobile-Satellite Service.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 2 2013-10-01 2013-10-01 false Licensing provisions for the non-voice, non... Stations § 25.142 Licensing provisions for the non-voice, non-geostationary Mobile-Satellite Service. (a... the non-voice, non-geostationary mobile-satellite service shall describe in detail the proposed non...

  6. 47 CFR 25.142 - Licensing provisions for the non-voice, non-geostationary mobile-satellite service.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 2 2012-10-01 2012-10-01 false Licensing provisions for the non-voice, non... Stations § 25.142 Licensing provisions for the non-voice, non-geostationary mobile-satellite service. (a... the non-voice, non-geostationary mobile-satellite service shall describe in detail the proposed non...

  7. 47 CFR 25.142 - Licensing provisions for the non-voice, non-geostationary mobile-satellite service.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 2 2010-10-01 2010-10-01 false Licensing provisions for the non-voice, non... Stations § 25.142 Licensing provisions for the non-voice, non-geostationary mobile-satellite service. (a... the non-voice, non-geostationary mobile-satellite service shall describe in detail the proposed non...

  8. Single non-invasive model to diagnose non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH).

    PubMed

    Otgonsuren, Munkhzul; Estep, Michael J; Hossain, Nayeem; Younossi, Elena; Frost, Spencer; Henry, Linda; Hunt, Sharon; Fang, Yun; Goodman, Zachary; Younossi, Zobair M

    2014-12-01

    Non-alcoholic steatohepatitis (NASH) is the progressive form of non-alcoholic fatty liver disease (NAFLD). A liver biopsy is considered the "gold standard" for diagnosing/staging NASH. Identification of NAFLD/NASH using non-invasive tools is important for intervention. The study aims were to: develop/validate the predictive performance of a non-invasive model (index of NASH [ION]); assess the performance of a recognized non-invasive model (fatty liver index [FLI]) compared with ION for NAFLD diagnosis; determine which non-invasive model (FLI, ION, or NAFLD fibrosis score [NFS]) performed best in predicting age-adjusted mortality. From the National Health and Nutrition Examination Survey III database, anthropometric, clinical, ultrasound, laboratory, and mortality data were obtained (n = 4458; n = 861 [19.3%] NAFLD by ultrasound) and used to develop the ION model, and then to compare the ION and FLI models for NAFLD diagnosis. For validation and diagnosis of NASH, liver biopsy data were used (n = 152). Age-adjusted Cox proportional hazard modeling estimated the association among the three non-invasive tests (FLI, ION, and NFS) and mortality. FLI's threshold score > 60 and ION's threshold score > 22 had similar specificity (FLI = 80% vs ION = 82%) for NAFLD diagnosis; FLI < 30 (80% sensitivity) and ION < 11 (81% sensitivity) excluded NAFLD. An ION score > 50 predicted histological NASH (92% specificity); the FLI model did not predict NASH or mortality. The ION model was best in predicting cardiovascular/diabetes-related mortality; NFS predicted overall or diabetes-related mortality. The ION model was superior in predicting NASH and mortality compared with the FLI model. Studies are needed to validate ION. © 2014 Journal of Gastroenterology and Hepatology Foundation and Wiley Publishing Asia Pty Ltd.

  9. Resource utilization for non-operative cervical radiculopathy: Management by surgeons versus non-surgeons.

    PubMed

    Chung, Sophie H; Bohl, Daniel D; Paul, Jonathan T; Rihn, Jeffrey A; Harrop, James S; Ghogawala, Zoher; Hilibrand, Alan S; Grauer, Jonathan N

    2017-07-01

    To compare the estimated resource utilization for non-operative treatment of cervical radiculopathy if managed by surgeons versus non-surgeons. A Cervical Spine Research Society-sponsored survey was administered at a national spine surgery conference to surgeons and non-surgeons, as classified above. The survey asked questions regarding resource utilization and perceived costs for the "average patient" with cervical radiculopathy managed non-operatively. Resource utilization and perceived costs were compared between surgeon and non-surgeon participants, and between private practice and academic and/or hybrid groups that combine academic and private practices. In total, 101 of the 125 conference attendees participated in the survey (return rate 80.8%, of which 60% were surgeons). Surgeon and non-surgeon estimates for duration of non-operative care did not differ (3.3 versus 4.2 months, p=0.071). Estimates also did not differ for estimated number of physical therapy visits (10.5 versus 10.5, p=0.983), cervical injections (1.4 versus 1.7, p=0.272), chiropractic visits (3.1 versus 3.7, p=0.583), or perceived days off from work (14.9 versus 16.3, p=0.816). The only difference identified was that surgeon estimates of the number of physician visits while providing non-operative care were lower than non-surgeon estimates (3.2 versus 4.0, p=0.018). In terms of estimated costs, surgeon and non-surgeon were mostly similar (only difference being that surgeon estimates for the total cost of physician visits per patient were lower than non-surgeon estimates ($382 versus $579, p=0.007). Surgeon estimates for the percent of their patients that go on to receive surgery within 6 months were higher than non-surgeon estimates (28.6% versus 18.8%, p=0.018). Similarly, surgeon estimates for the percent of their patients to go on to receive surgery within 2 years were higher than non-surgeon estimates (37.8% versus 24.8%, p=0.013). Academic/hybrid and private practice group resource

  10. An outbreak of enterically transmitted non-A, non-B hepatitis in Pakistan.

    PubMed

    Iqbal, M; Ahmed, A; Qamar, A; Dixon, K; Duncan, J F; Islam, N U; Rauf, A; Bryan, J P; Malik, I A; Legters, L J

    1989-04-01

    An epidemic of enterically transmitted non-A, non-B hepatitis occurred at a college in Sargodha, Pakistan in early 1987. There were 133 clinical cases, an attack rate of approximately 20%. Though the disease was relatively mild, all clinical cases required hospitalization and prolonged convalescence. Nearly all cases were associated with a single water source. The epidemic ended when the water supply was improved. This is the 4th described epidemic of non-A, non-B hepatitis in Pakistan.

  11. Non-invasive spectroscopic techniques in the diagnosis of non-melanoma skin cancer

    NASA Astrophysics Data System (ADS)

    Drakaki, E.; Sianoudis, IA; Zois, EN; Makropoulou, M.; Serafetinides, AA; Dessinioti, C.; Stefanaki, E.; Stratigos, AJ; Antoniou, C.; Katsambas, A.; Christofidou, E.

    2017-11-01

    The number of non-melanoma skin cancers is increasing worldwide and has become an important health and economic issue. Early detection and treatment of skin cancer can significantly improve patient outcome. Therefore there is an increase in the demand for proper management and effective non-invasive diagnostic modalities in order to avoid relapses or unnecessary treatments. Although the gold standard of diagnosis for non-melanoma skin cancers is biopsy followed by histopathology evaluation, optical non-invasive diagnostic tools have obtained increased attention. Emerging non-invasive or minimal invasive techniques with possible application in the diagnosis of non-melanoma skin cancers include high-definition optical coherence tomography, fluorescence spectroscopy, oblique incidence diffuse reflectance spectrometry among others spectroscopic techniques. Our findings establish how those spectrometric techniques can be used to more rapidly and easily diagnose skin cancer in an accurate and automated manner in the clinic.

  12. Nonstate Security Threats in Africa: Challenges for U.S. Engagement

    DTIC Science & Technology

    2010-12-01

    kidnapping instead le SAge PRISM 2, no. 1 FeatuReS | 67 East Asia has led to a spike in elephant poach - ing. In June 2002, Singapore seized 6.2 metric...thousands of people in a country with no functioning cen- tral government since the 1980s.23 In addition to the impact on the lives and families of...percent of U.S. for- eign oil imports by 2015,25 and militant attacks impacting West African oil already affect the price of oil on global stock markets

  13. Watch out for reporter gene assays with Renilla luciferase and paclitaxel.

    PubMed

    Theile, Dirk; Spalwisz, Adriana; Weiss, Johanna

    2013-06-15

    Luminescence-based reporter gene assays are widely used in biochemistry. Signals from reporter genes (e.g., firefly luminescence) are usually normalized to signals from constantly luminescing luciferases such as Renilla luciferase. This normalization step can be performed by modern luminometry devices automatically providing final results. Here we demonstrate paclitaxel to strikingly enhance Renilla luminescence, thereby potentially flawing results from reporter gene assays. In consequence, these data advocate for careful examination of raw data and militate against automatic data processing. Copyright © 2013 Elsevier Inc. All rights reserved.

  14. Promoting a culture of innovation: BJSP and the emergence of new paradigms in social psychology.

    PubMed

    Reicher, Stephen

    2011-09-01

    In this paper, I start by describing the role played by British Journal of Social Psychology (BJSP) in nurturing two important new paradigms in social psychology - the social identity approach and discourse psychology. I then consider the forces in contemporary academia, in general, and psychology, in particular, that militate against innovation. I conclude by suggesting some ways in which individual social psychologists and our journals, particularly BJSP, can contribute to the development of an innovative and intellectually dynamic discipline. ©2011 The British Psychological Society.

  15. Non-invasive Diagnosis of Fibrosis in Non-alcoholic Fatty Liver Disease

    PubMed Central

    Arora, Anil; Sharma, Praveen

    2012-01-01

    Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in developed as well as in developing countries. Its prevalence continues to rise currently affecting approximately 20-30% of adults and 10% of children in the United States. Non-alcoholic fatty liver disease represents a wide spectrum of conditions ranging from fatty liver, which in general follows a benign non-progressive clinical course, to non-alcoholic steatohepatitis (NASH), a more serious form of NAFLD that may progress to cirrhosis and end-stage liver disease. Liver biopsy remains the gold standard for evaluating the degree of hepatic necroinflammation and fibrosis; however, several non-invasive investigations, such as serum biomarkers, have been developed to establish the diagnosis and also to evaluate treatment response. There has been a substantial development of non-invasive risk scores, biomarker panels, and radiological modalities to identify at risk patients with NAFLD without recourse to liver biopsy on a routine basis. Examples include combination of serum markers like NAFLD fibrosis score (NFS), BARD score, fibrometer, FIB4, and non-invasive tools like fibroscan which assess fibrosis in patients with NAFLD. Other markers of fibrosis that have been evaluated include high-sensitivity C-reactive protein, plasma pentraxin 3, interleukin-6, and cytokeratin-18. This review focuses on the methods currently available in daily clinical practice in hepatology and touches briefly on the potential future markers under investigation. PMID:25755423

  16. Non-Toxic, Non-Flammable, -80 C Phase Change Materials

    NASA Technical Reports Server (NTRS)

    Cutbirth, J. Michael

    2013-01-01

    The objective of this effort was to develop a non-toxic, non-flammable, -80 C phase change material (PCM) to be used in NASA's ICEPAC capsules for biological sample preservation in flight to and from Earth orbit. A temperature of about -68 C or lower is a critical temperature for maintaining stable cell, tissue, and cell fragment storage.

  17. 10 CFR 436.16 - Establishing non-fuel and non-water cost categories.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 3 2010-01-01 2010-01-01 false Establishing non-fuel and non-water cost categories. 436.16 Section 436.16 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION FEDERAL ENERGY MANAGEMENT AND PLANNING PROGRAMS Methodology and Procedures for Life Cycle Cost Analyses § 436.16 Establishing non-fuel...

  18. To the theory of non-local non-isothermal filtration in porous medium

    NASA Astrophysics Data System (ADS)

    Meilanov, R. R.; Akhmedov, E. N.; Beybalaev, V. D.; Magomedov, R. A.; Ragimkhanov, G. B.; Aliverdiev, A. A.

    2018-01-01

    A new approach to the theory of non-local and non-isothermal filtration based on the mathematical apparatus of fractional order derivatives is developing. A solution of the Cauchy problem for the system of equations of non-local non-isothermal filtration in fractional calculus is obtained. Some applications of the solutions obtained to the problems of underground hydrodynamics (fracturing and explosion) are considered. A computational experiment was carried out to analyze the solutions obtained. Graphs of pressure and temperature dependences are plotted against time.

  19. Non-Compact Cardiomyopathy or Ventricular Non-Compact Syndrome?

    PubMed Central

    2014-01-01

    Ventricular myocardial non-compaction has been recognized and defined as a genetic cardiomyopathy by American Heart Association since 2006. The argument on the nomenclature and pathogenesis of this kind of ventricular myocardial non-compaction characterized by regional ventricular wall thickening and deep trabecular recesses often complicated with chronic heart failure, arrhythmia and thromboembolism and usually overlap the genetics and phenotypes of other kind of genetic or mixed cardiomyopathy still exist. The proper classification and correct nomenclature of the non-compact ventricles will contribute to the precisely and completely understanding of etiology and its related patho-physiological mechanism for a better risk stratification and more personalized therapy of the disease individually. All of the genetic heterogeneity and phenotypical overlap and the variety in histopathological, electromechanical and clinical presentation indicates that some of the cardiomyopathies might just be the different consequence of myocardial development variations related to gene mutation and phenotype of one or group genes induced by the interacted and disturbed process of gene modulation at different links of gene function expression and some other etiologies. This review aims to establish a new concept of "ventricular non-compaction syndrome" based on the demonstration of the current findings of etiology, epidemiology, histopathology and echocardiography related to the disorder of ventricular myocardial compaction and myocardial electromechanical function development. PMID:25580189

  20. Risk factors for non-alcoholic fatty liver disease are common in patients with non-B non-C hepatocellular carcinoma in India.

    PubMed

    David, Deepu; Raghavendran, Anantharam; Goel, Ashish; Bharath Kumar, C; Kodiatte, Thomas Alex; Burad, Deepak; Abraham, Priya; Ramakrishna, Banumathi; Joseph, Philip; Ramachandran, Jeyamani; Eapen, C E

    2017-09-01

    The aim of the study was to analyze the prevalence of risk factors for non-alcoholic fatty liver disease (NAFLD) in patients with non-B non-C hepatocellular carcinoma (HCC). Between June 2012 and November 2014, patients with HCC, negative for hepatitis B surface antigen and hepatitis C virus antibody, were included in this study. All patients were assessed for risk factors for NAFLD such as diabetes mellitus (DM), hypertension, dyslipidemia, metabolic syndrome, and obesity. Forty-seven patients with non-B non-C HCC (males, 37; age, 60±10 years; mean±SD) were studied. Model for end-stage liver disease score was 11±4. Twenty-five patients were in Child's class A. History of significant alcohol intake was noted in 11 (23%) patients. Prevalence of risk factors for NAFLD were obesity 24 (51%), DM 22 (47%), metabolic syndrome 21 (45%), hypertension 16 (34%), and dyslipidemia 13 (28%). Forty (85%) patients had at least one risk factor for NAFLD. The mean duration of at least one NAFLD risk factor was 7.5 years, prior to diagnosis of HCC. Thirteen (28%) patients were positive for anti-HBc; however, none of the study patients had detectable HBV DNA in blood. Eighty-five percent of the patients with non-B non-C HCC had at least one risk factor for NAFLD. None of the study patients had occult hepatitis B infection. NAFLD is emerging as the major etiological contributing factor for non-B non-C HCC in India.

  1. Non-equilibrium supramolecular polymerization.

    PubMed

    Sorrenti, Alessandro; Leira-Iglesias, Jorge; Markvoort, Albert J; de Greef, Tom F A; Hermans, Thomas M

    2017-09-18

    Supramolecular polymerization has been traditionally focused on the thermodynamic equilibrium state, where one-dimensional assemblies reside at the global minimum of the Gibbs free energy. The pathway and rate to reach the equilibrium state are irrelevant, and the resulting assemblies remain unchanged over time. In the past decade, the focus has shifted to kinetically trapped (non-dissipative non-equilibrium) structures that heavily depend on the method of preparation (i.e., pathway complexity), and where the assembly rates are of key importance. Kinetic models have greatly improved our understanding of competing pathways, and shown how to steer supramolecular polymerization in the desired direction (i.e., pathway selection). The most recent innovation in the field relies on energy or mass input that is dissipated to keep the system away from the thermodynamic equilibrium (or from other non-dissipative states). This tutorial review aims to provide the reader with a set of tools to identify different types of self-assembled states that have been explored so far. In particular, we aim to clarify the often unclear use of the term "non-equilibrium self-assembly" by subdividing systems into dissipative, and non-dissipative non-equilibrium states. Examples are given for each of the states, with a focus on non-dissipative non-equilibrium states found in one-dimensional supramolecular polymerization.

  2. Non-occupational physical activity levels of shift workers compared with non-shift workers

    PubMed Central

    Loef, Bette; Hulsegge, Gerben; Wendel-Vos, G C Wanda; Verschuren, W M Monique; Bakker, Marije F; van der Beek, Allard J; Proper, Karin I

    2017-01-01

    Objectives Lack of physical activity (PA) has been hypothesised as an underlying mechanism in the adverse health effects of shift work. Therefore, our aim was to compare non-occupational PA levels between shift workers and non-shift workers. Furthermore, exposure–response relationships for frequency of night shifts and years of shift work regarding non-occupational PA levels were studied. Methods Data of 5980 non-shift workers and 532 shift workers from the European Prospective Investigation into Cancer and Nutrition-Netherlands (EPIC-NL) were used in these cross-sectional analyses. Time spent (hours/week) in different PA types (walking/cycling/exercise/chores) and intensities (moderate/vigorous) were calculated based on self-reported PA. Furthermore, sports were operationalised as: playing sports (no/yes), individual versus non-individual sports, and non-vigorous-intensity versus vigorous-intensity sports. PA levels were compared between shift workers and non-shift workers using Generalized Estimating Equations and logistic regression. Results Shift workers reported spending more time walking than non-shift workers (B=2.3 (95% CI 1.2 to 3.4)), but shift work was not associated with other PA types and any of the sports activities. Shift workers who worked 1–4 night shifts/month (B=2.4 (95% CI 0.6 to 4.3)) and ≥5 night shifts/month (B=3.7 (95% CI 1.8 to 5.6)) spent more time walking than non-shift workers. No exposure–response relationships were found between years of shift work and PA levels. Conclusions Shift workers spent more time walking than non-shift workers, but we observed no differences in other non-occupational PA levels. To better understand if and how PA plays a role in the negative health consequences of shift work, our findings need to be confirmed in future studies. PMID:27872151

  3. Non-unitarity, sterile neutrinos, and non-standard neutrino interactions

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Blennow, Mattias; Coloma, Pilar; Fernandez-Martinez, Enrique

    The simplest Standard Model extension to explain neutrino masses involves the addition of right-handed neutrinos. At some level, this extension will impact neutrino oscillation searches. In this work we explore the differences and similarities between the case in which these neutrinos are kinematically accessible (sterile neutrinos) or not (mixing matrix non-unitarity). We clarify apparent inconsistencies in the present literature when using different parametrizations to describe these effects and recast both limits in the popular neutrino non-standard interaction (NSI) formalism. We find that, in the limit in which sterile oscillations are averaged out at the near detector, their effects at themore » far detector coincide with non-unitarity at leading order, even in presence of a matter potential. We also summarize the present bounds existing in both limits and compare them with the expected sensitivities of near future facilities taking the DUNE proposal as a benchmark. We conclude that non-unitarity effects are too constrained to impact present or near future neutrino oscillation facilities but that sterile neutrinos can play an important role at long baseline experiments. As a result, the role of the near detector is also discussed in detail.« less

  4. Non-unitarity, sterile neutrinos, and non-standard neutrino interactions

    DOE PAGES

    Blennow, Mattias; Coloma, Pilar; Fernandez-Martinez, Enrique; ...

    2017-04-27

    The simplest Standard Model extension to explain neutrino masses involves the addition of right-handed neutrinos. At some level, this extension will impact neutrino oscillation searches. In this work we explore the differences and similarities between the case in which these neutrinos are kinematically accessible (sterile neutrinos) or not (mixing matrix non-unitarity). We clarify apparent inconsistencies in the present literature when using different parametrizations to describe these effects and recast both limits in the popular neutrino non-standard interaction (NSI) formalism. We find that, in the limit in which sterile oscillations are averaged out at the near detector, their effects at themore » far detector coincide with non-unitarity at leading order, even in presence of a matter potential. We also summarize the present bounds existing in both limits and compare them with the expected sensitivities of near future facilities taking the DUNE proposal as a benchmark. We conclude that non-unitarity effects are too constrained to impact present or near future neutrino oscillation facilities but that sterile neutrinos can play an important role at long baseline experiments. As a result, the role of the near detector is also discussed in detail.« less

  5. Proportion and clinical characteristics of non-asthmatic non-smokers among adults with airflow obstruction.

    PubMed

    Takiguchi, Hiroto; Takeuchi, Tomoe; Niimi, Kyoko; Tomomatsu, Hiromi; Tomomatsu, Katsuyoshi; Hayama, Naoki; Oguma, Tsuyoshi; Aoki, Takuya; Urano, Tetsuya; Asai, Satomi; Miyachi, Hayato; Asano, Koichiro

    2018-01-01

    Chronic obstructive pulmonary disease (COPD) mainly develops after long-term exposure to cigarette or biomass fuel smoke, but also occurs in non-smokers with or without a history of asthma. We investigated the proportion and clinical characteristics of non-smokers among middle-aged to elderly subjects with airflow obstruction. We retrospectively analyzed 1,892 subjects aged 40-89 years who underwent routine preoperative spirometry at a tertiary university hospital in Japan. Airflow obstruction was defined as a forced expiratory volume in 1 second (FEV1)/forced vital capacity < 0.7 or as the lower limit of the normal. Among 323 patients presenting with FEV1/forced vital capacity < 0.7, 43 had asthma and 280 did not. Among the non-asthmatic patients with airflow obstruction, 94 (34%) were non-smokers. A larger number of women than men with airflow obstruction had asthma (26% vs. 7.6%, p < 0.001), or were non-smokers among non-asthmatics (72% vs. 20%, p < 0.001). Non-asthmatic non-smokers, rather than non-asthmatic smokers, asthmatic non-smokers, and asthmatic smokers, exhibited better pulmonary function (median FEV1: 79% of predicted FEV1 vs. 73%, 69%, and 66%, respectively, p = 0.005) and less dyspnea on exertion (1% vs. 12%, 12%, and 28%, respectively, p = 0.001). Pulmonary emphysema on thoracic computed tomography was less common in non-smokers (p < 0.001). Using the lower limit of the normal to define airflow obstruction yielded similar results. There are a substantial number of non-smokers with airflow obstruction compatible with COPD in Japan. In this study, airflow obstruction in non-smokers was more common in women and likelier to result in mild functional and pathological abnormalities than in smokers. Further studies are warranted to investigate the long-term prognosis and appropriate management of this population in developed countries, especially in women.

  6. Preventing mother-to-child transmission: factors affecting mothers' choice of feeding--a case study from Cameroon.

    PubMed

    Muko, K N; Tchangwe, G K; Ngwa, V C; Njoya, L

    2004-11-01

    This paper reports on factors influencing the decision of mothers regarding the type of feeding method for their babies in a rural setting in Cameroon. The aim of the study was to ascertain the proportion of mothers choosing the different methods of feeding, to determine the various factors influencing their choices, and to ascertain the relationships of these factors to their respective choices. Questionnaires were used on 108 HIV-positive mothers who had delivered babies and who were administered nevirapine at least 3 months prior to the study. A focus group discussion with mothers also took place. Findings were that more mothers (84%) chose breastfeeding than artificial feeding (16%), while a minority (4%) selected mixed feeding. Factors found to militate against artificial feeding were cost (69%), stigma (64%), family pressure (44%), inconvenience in preparation/administration (38%), prior education from health workers (23%), and loss of special attention from family (8%). On the other hand, advice of health worker (44%), ill health (19.5%), free milk (12.5%),job pressure (12.5%) and loss of beauty (12.5%) were found to militate against breastfeeding. A direct relationship was also found between age, educational level, income size, marital status and choice of feeding. Policies targeting stigma reduction and socio-cultural factors affecting the choice of feeding are needed to optimise uptake of the less risky methods of feeding which could in turn contribute to a reduction in transmission.

  7. Non-equilibrium supramolecular polymerization

    PubMed Central

    Sorrenti, Alessandro; Leira-Iglesias, Jorge; Markvoort, Albert J.

    2017-01-01

    Supramolecular polymerization has been traditionally focused on the thermodynamic equilibrium state, where one-dimensional assemblies reside at the global minimum of the Gibbs free energy. The pathway and rate to reach the equilibrium state are irrelevant, and the resulting assemblies remain unchanged over time. In the past decade, the focus has shifted to kinetically trapped (non-dissipative non-equilibrium) structures that heavily depend on the method of preparation (i.e., pathway complexity), and where the assembly rates are of key importance. Kinetic models have greatly improved our understanding of competing pathways, and shown how to steer supramolecular polymerization in the desired direction (i.e., pathway selection). The most recent innovation in the field relies on energy or mass input that is dissipated to keep the system away from the thermodynamic equilibrium (or from other non-dissipative states). This tutorial review aims to provide the reader with a set of tools to identify different types of self-assembled states that have been explored so far. In particular, we aim to clarify the often unclear use of the term “non-equilibrium self-assembly” by subdividing systems into dissipative, and non-dissipative non-equilibrium states. Examples are given for each of the states, with a focus on non-dissipative non-equilibrium states found in one-dimensional supramolecular polymerization. PMID:28349143

  8. Non-transecting bulbar urethroplasty

    PubMed Central

    Andrich, Daniela E.; Mundy, Anthony R.

    2015-01-01

    Excision and end-to-end anastomosis (EPA) has been the preferred urethroplasty technique for short bulbar strictures and is associated with an excellent functional outcome. Driven by concerns over the potential morbidity associated with dividing the urethra, therefore compromising spongiosal blood flow, as well as spongiofibrosis being superficial in the majority of non-traumatic bulbar strictures, the non-transecting technique for bulbar urethroplasty has been developed with the aim of achieving the same success as EPA without the morbidity associated with transection. This manuscript highlights the fundamental principles underlying the ongoing debate—transection or non-transection of the strictured bulbar urethra? The potential advantages of avoiding dividing the corpus spongiosum of the urethra are discussed. The non-transecting anastomotic procedure together with its various modifications are decribed in detail. Our experience with this technique is presented. Non-transecting excision of spongiofibrosis with preservation of well vascularised underlying spongiosum provides an excellent alternative to dividing the urethra during urethroplasty for short non-traumatic proximal bulbar strictures. PMID:26816808

  9. Non-occupational physical activity levels of shift workers compared with non-shift workers.

    PubMed

    Loef, Bette; Hulsegge, Gerben; Wendel-Vos, G C Wanda; Verschuren, W M Monique; Vermeulen, Roel C H; Bakker, Marije F; van der Beek, Allard J; Proper, Karin I

    2017-05-01

    Lack of physical activity (PA) has been hypothesised as an underlying mechanism in the adverse health effects of shift work. Therefore, our aim was to compare non-occupational PA levels between shift workers and non-shift workers. Furthermore, exposure-response relationships for frequency of night shifts and years of shift work regarding non-occupational PA levels were studied. Data of 5980 non-shift workers and 532 shift workers from the European Prospective Investigation into Cancer and Nutrition-Netherlands (EPIC-NL) were used in these cross-sectional analyses. Time spent (hours/week) in different PA types (walking/cycling/exercise/chores) and intensities (moderate/vigorous) were calculated based on self-reported PA. Furthermore, sports were operationalised as: playing sports (no/yes), individual versus non-individual sports, and non-vigorous-intensity versus vigorous-intensity sports. PA levels were compared between shift workers and non-shift workers using Generalized Estimating Equations and logistic regression. Shift workers reported spending more time walking than non-shift workers (B=2.3 (95% CI 1.2 to 3.4)), but shift work was not associated with other PA types and any of the sports activities. Shift workers who worked 1-4 night shifts/month (B=2.4 (95% CI 0.6 to 4.3)) and ≥5 night shifts/month (B=3.7 (95% CI 1.8 to 5.6)) spent more time walking than non-shift workers. No exposure-response relationships were found between years of shift work and PA levels. Shift workers spent more time walking than non-shift workers, but we observed no differences in other non-occupational PA levels. To better understand if and how PA plays a role in the negative health consequences of shift work, our findings need to be confirmed in future studies. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  10. "Selective" switching from non-selective to selective non-steroidal anti-inflammatory drugs.

    PubMed

    Bennett, Kathleen; Teeling, Mary; Feely, John

    2003-11-01

    Non-steroidal anti inflammatory drugs (NSAIDs) are thought to account for almost 25% of all reported adverse drug reactions, primarily gastrointestinal (GI) toxicity. Selective cyclo-oxygenase-2 (COX-2) inhibitors have been shown to preferentially inhibit activity of the COX-2 enzyme, which maintains anti-inflammatory activity but reduces GI toxicity. To determine the degree of switching from non-selective NSAIDs to COX-2 inhibitors and to examine the factors that were associated with switching. The General Medical Services prescription database (1.2 million people) was examined for NSAID prescriptions from December 1999 through November 2001. All those receiving non-selective NSAIDs and those switching to selective COX-2 inhibitors after at least 1 month on a non-selective NSAID were identified (non-switchers and switchers, respectively). Age, sex, dose of non-selective NSAID and co-prescribing of anti-peptic ulcer (anti-PU) drugs were considered between switchers and non-switchers, and odds ratios (OR) calculated using logistic regression. The effect of chronic use (> or =3 months prescription of a non-selective NSAID during the study period) on switching was also evaluated. A total of 81,538 of 480,573 patients (17%) initially prescribed non-selective NSAIDs were switched to COX-2 inhibitors during the study. The elderly (65 years or older) were more likely to be switched to a COX-2 inhibitor [OR=1.81, 95% confidence interval (CI) 1.79, 1.84]. Women were also more likely to be switched to COX-2 inhibitor therapy (OR=1.25, 95% CI 1.23, 1.27). Previous but not subsequent prescribing of anti-PU drugs was also associated with switching. Chronic users showed similar switching patterns. Prescribers are more likely to switch older female patients and those with a past history of peptic ulcers from non-selective NSAIDs to COX-2 inhibitors. This suggests that doctors take risk factors into consideration when prescribing NSAIDs. The relatively low rate of switching may

  11. Funkmesstechnik

    NASA Astrophysics Data System (ADS)

    Plaßmann, Wilfried

    Ein Hauptgebiet der Funkmesstechnik ist durch den Begriff RADAR (radio detection and ranging gekennzeichnet. Bei diesem Verfahren werden impulsförmige elektromagnetische Wellen von einer Antenne ausgesendet und an Körpern oder Stoffverteilungen (Wolken) reflektiert. Die Sendeantenne wird auf Empfang umgeschaltet, und anhand des Echos sind Rückschlüsse auf die Lage und die Beschaffenheit der Körper oder der Stoffverteilungen möglich. Angewendet wird die Radartechnik bei der Kontrolle und der Sicherung des Land-, Wasser- und Flugverkehrs, in der Meteorologie zur Wetterprognose, in der Astrologie und im militärischen Bereich.

  12. Proportion and clinical characteristics of non-asthmatic non-smokers among adults with airflow obstruction

    PubMed Central

    Takiguchi, Hiroto; Takeuchi, Tomoe; Niimi, Kyoko; Tomomatsu, Hiromi; Tomomatsu, Katsuyoshi; Hayama, Naoki; Oguma, Tsuyoshi; Urano, Tetsuya; Asai, Satomi; Miyachi, Hayato; Asano, Koichiro

    2018-01-01

    Background and objectives Chronic obstructive pulmonary disease (COPD) mainly develops after long-term exposure to cigarette or biomass fuel smoke, but also occurs in non-smokers with or without a history of asthma. We investigated the proportion and clinical characteristics of non-smokers among middle-aged to elderly subjects with airflow obstruction. Methods We retrospectively analyzed 1,892 subjects aged 40–89 years who underwent routine preoperative spirometry at a tertiary university hospital in Japan. Airflow obstruction was defined as a forced expiratory volume in 1 second (FEV1)/forced vital capacity < 0.7 or as the lower limit of the normal. Results Among 323 patients presenting with FEV1/forced vital capacity < 0.7, 43 had asthma and 280 did not. Among the non-asthmatic patients with airflow obstruction, 94 (34%) were non-smokers. A larger number of women than men with airflow obstruction had asthma (26% vs. 7.6%, p < 0.001), or were non-smokers among non-asthmatics (72% vs. 20%, p < 0.001). Non-asthmatic non-smokers, rather than non-asthmatic smokers, asthmatic non-smokers, and asthmatic smokers, exhibited better pulmonary function (median FEV1: 79% of predicted FEV1 vs. 73%, 69%, and 66%, respectively, p = 0.005) and less dyspnea on exertion (1% vs. 12%, 12%, and 28%, respectively, p = 0.001). Pulmonary emphysema on thoracic computed tomography was less common in non-smokers (p < 0.001). Using the lower limit of the normal to define airflow obstruction yielded similar results. Conclusions There are a substantial number of non-smokers with airflow obstruction compatible with COPD in Japan. In this study, airflow obstruction in non-smokers was more common in women and likelier to result in mild functional and pathological abnormalities than in smokers. Further studies are warranted to investigate the long-term prognosis and appropriate management of this population in developed countries, especially in women. PMID:29742176

  13. 47 CFR 25.259 - Time sharing between NOAA meteorological satellite systems and non-voice, non-geostationary...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... satellite systems and non-voice, non-geostationary satellite systems in the 137-138 MHz band. 25.259 Section... systems and non-voice, non-geostationary satellite systems in the 137-138 MHz band. (a) The space stations of a non-voice, non-geostationary Mobile-Satellite Service (NVNG MSS) system time-sharing downlink...

  14. 47 CFR 25.259 - Time sharing between NOAA meteorological satellite systems and non-voice, non-geostationary...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... satellite systems and non-voice, non-geostationary satellite systems in the 137-138 MHz band. 25.259 Section... systems and non-voice, non-geostationary satellite systems in the 137-138 MHz band. (a) The space stations of a non-voice, non-geostationary Mobile-Satellite Service (NVNG MSS) system time-sharing downlink...

  15. Non-dreamers.

    PubMed

    Pagel, J F

    2003-05-01

    Assess incidence and clarify whether diagnostic correlates exist for sleep laboratory patients reporting a lack of dream recall. To awaken, during polysomnographically defined sleep including rapid eye movement (REM) sleep, individuals reporting never having experienced a dream, and determine whether they report dreaming. Study # 1 - Incidence and polysomnographic correlates of sleep lab patients responding on questionnaire that they had never experienced dreaming. Study # 2 - Phone interviews with those individuals reporting non-dreaming on questionnaire to reassess incidence. Study # 3 - After reassessment, individuals (non-dreamers - # 16) are awakened during polysomnographic defined sleep (including REM sleep) and queried about dream recall. This group is compared statistically to a group (rare-dreamers - # 12) that reported dreaming as an extremely rare occurrence (mean dream recall latency - 13.5 years). Study # 1: Incidence of questionnaire reported non-dreaming in this sleep laboratory population is 6.5% (N=534) and is associated with the diagnosis of obstructive sleep apnea (specificity 95.6% for respiratory disturbance index >15). Study # 2 - Individuals who report after interview to have never experienced dreaming are more unusual (0.38% of this sleep laboratory population). Study # 3 - None of the non-dreamers (# 16) reported dream recall after waking in the sleep laboratory (36 awakenings in total for this group). This group does not differ, based on polysomnographic, clinical, or demographic variables, from the rare-dreaming group that occasionally reported dreams when awakened (3/12 patients, 3/32 awakenings) - a finding consistent with the reports of previous studies. The experience of dreaming may not be as ubiquitous as generally accepted. The group of non-dreamers evaluated in this study reports never having recalled a dream and reports no dreams when awakened during polysomnographicly defined sleep. These individuals might not experience

  16. 47 CFR 25.259 - Time sharing between NOAA meteorological satellite systems and non-voice, non-geostationary...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... satellite systems and non-voice, non-geostationary satellite systems in the 137-138 MHz band. 25.259 Section... systems and non-voice, non-geostationary satellite systems in the 137-138 MHz band. (a) A non-voice, non-geostationary mobile-satellite service system licensee (“NVNG licensee”) time-sharing spectrum in the 137-138...

  17. 47 CFR 25.259 - Time sharing between NOAA meteorological satellite systems and non-voice, non-geostationary...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... satellite systems and non-voice, non-geostationary satellite systems in the 137-138 MHz band. 25.259 Section... systems and non-voice, non-geostationary satellite systems in the 137-138 MHz band. (a) A non-voice, non-geostationary mobile-satellite service system licensee (“NVNG licensee”) time-sharing spectrum in the 137-138...

  18. 47 CFR 25.259 - Time sharing between NOAA meteorological satellite systems and non-voice, non-geostationary...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... satellite systems and non-voice, non-geostationary satellite systems in the 137-138 MHz band. 25.259 Section... systems and non-voice, non-geostationary satellite systems in the 137-138 MHz band. (a) A non-voice, non-geostationary mobile-satellite service system licensee (“NVNG licensee”) time-sharing spectrum in the 137-138...

  19. Role of non-coding RNAs in non-aging-related neurological disorders.

    PubMed

    Vieira, A S; Dogini, D B; Lopes-Cendes, I

    2018-06-11

    Protein coding sequences represent only 2% of the human genome. Recent advances have demonstrated that a significant portion of the genome is actively transcribed as non-coding RNA molecules. These non-coding RNAs are emerging as key players in the regulation of biological processes, and act as "fine-tuners" of gene expression. Neurological disorders are caused by a wide range of genetic mutations, epigenetic and environmental factors, and the exact pathophysiology of many of these conditions is still unknown. It is currently recognized that dysregulations in the expression of non-coding RNAs are present in many neurological disorders and may be relevant in the mechanisms leading to disease. In addition, circulating non-coding RNAs are emerging as potential biomarkers with great potential impact in clinical practice. In this review, we discuss mainly the role of microRNAs and long non-coding RNAs in several neurological disorders, such as epilepsy, Huntington disease, fragile X-associated ataxia, spinocerebellar ataxias, amyotrophic lateral sclerosis (ALS), and pain. In addition, we give information about the conditions where microRNAs have demonstrated to be potential biomarkers such as in epilepsy, pain, and ALS.

  20. Capacitive Sensing for Non-Invasive Breathing and Heart Monitoring in Non-Restrained, Non-Sedated Laboratory Mice.

    PubMed

    González-Sánchez, Carlos; Fraile, Juan-Carlos; Pérez-Turiel, Javier; Damm, Ellen; Schneider, Jochen G; Zimmermann, Heiko; Schmitt, Daniel; Ihmig, Frank R

    2016-07-07

    Animal testing plays a vital role in biomedical research. Stress reduction is important for improving research results and increasing the welfare and the quality of life of laboratory animals. To estimate stress we believe it is of great importance to develop non-invasive techniques for monitoring physiological signals during the transport of laboratory animals, thereby allowing the gathering of information on the transport conditions, and, eventually, the improvement of these conditions. Here, we study the suitability of commercially available electric potential integrated circuit (EPIC) sensors, using both contact and contactless techniques, for monitoring the heart rate and breathing rate of non-restrained, non-sedated laboratory mice. The design has been tested under different scenarios with the aim of checking the plausibility of performing contactless capture of mouse heart activity (ideally with an electrocardiogram). First experimental results are shown.

  1. A novel framework to simulating non-stationary, non-linear, non-Normal hydrological time series using Markov Switching Autoregressive Models

    NASA Astrophysics Data System (ADS)

    Birkel, C.; Paroli, R.; Spezia, L.; Tetzlaff, D.; Soulsby, C.

    2012-12-01

    In this paper we present a novel model framework using the class of Markov Switching Autoregressive Models (MSARMs) to examine catchments as complex stochastic systems that exhibit non-stationary, non-linear and non-Normal rainfall-runoff and solute dynamics. Hereby, MSARMs are pairs of stochastic processes, one observed and one unobserved, or hidden. We model the unobserved process as a finite state Markov chain and assume that the observed process, given the hidden Markov chain, is conditionally autoregressive, which means that the current observation depends on its recent past (system memory). The model is fully embedded in a Bayesian analysis based on Markov Chain Monte Carlo (MCMC) algorithms for model selection and uncertainty assessment. Hereby, the autoregressive order and the dimension of the hidden Markov chain state-space are essentially self-selected. The hidden states of the Markov chain represent unobserved levels of variability in the observed process that may result from complex interactions of hydroclimatic variability on the one hand and catchment characteristics affecting water and solute storage on the other. To deal with non-stationarity, additional meteorological and hydrological time series along with a periodic component can be included in the MSARMs as covariates. This extension allows identification of potential underlying drivers of temporal rainfall-runoff and solute dynamics. We applied the MSAR model framework to streamflow and conservative tracer (deuterium and oxygen-18) time series from an intensively monitored 2.3 km2 experimental catchment in eastern Scotland. Statistical time series analysis, in the form of MSARMs, suggested that the streamflow and isotope tracer time series are not controlled by simple linear rules. MSARMs showed that the dependence of current observations on past inputs observed by transport models often in form of the long-tailing of travel time and residence time distributions can be efficiently explained by

  2. Non-Cartesian Parallel Imaging Reconstruction

    PubMed Central

    Wright, Katherine L.; Hamilton, Jesse I.; Griswold, Mark A.; Gulani, Vikas; Seiberlich, Nicole

    2014-01-01

    Non-Cartesian parallel imaging has played an important role in reducing data acquisition time in MRI. The use of non-Cartesian trajectories can enable more efficient coverage of k-space, which can be leveraged to reduce scan times. These trajectories can be undersampled to achieve even faster scan times, but the resulting images may contain aliasing artifacts. Just as Cartesian parallel imaging can be employed to reconstruct images from undersampled Cartesian data, non-Cartesian parallel imaging methods can mitigate aliasing artifacts by using additional spatial encoding information in the form of the non-homogeneous sensitivities of multi-coil phased arrays. This review will begin with an overview of non-Cartesian k-space trajectories and their sampling properties, followed by an in-depth discussion of several selected non-Cartesian parallel imaging algorithms. Three representative non-Cartesian parallel imaging methods will be described, including Conjugate Gradient SENSE (CG SENSE), non-Cartesian GRAPPA, and Iterative Self-Consistent Parallel Imaging Reconstruction (SPIRiT). After a discussion of these three techniques, several potential promising clinical applications of non-Cartesian parallel imaging will be covered. PMID:24408499

  3. [Medical and economic evaluation of donated blood screening for hepatitis C and non-A, non-B, non-C hepatitis].

    PubMed

    Vergnon, P; Colin, C; Jullien, A M; Bory, E; Excoffier, S; Matillon, Y; Trepo, C

    1996-01-01

    The aim of this study was to evaluate the cost of hepatitis C and non-A non-B non-C screening strategy in donated blood, currently used in French transfusion centres and to assess the effect in the blood transfusion centres according to the prevalence of the disease and the intrinsec values of tests. This screening strategy was based on alanine aminotransferase assay, and HBc and HCV antibodies detection. In 1993, a survey was conducted in 26 French transfusion centers to estimate the costs of the screening strategy currently used. Average expenditure on diagnostic sets, equipment, staff and administration charges for hepatitis C and non-A non-B non-C screening were calculated. From these results, we estimated the cost of the previous strategy which did not involve HCV antibody testing, so as to determine the incremental cost between the two strategies. We used clinical decision analysis and sensitivity analysis to estimate the incremental cost-effectiveness ratio with data gathered from the literature and examine the impact on blood transfusion centre. Implemented for 100,000 volunteer blood donations, the incremental cost of the new strategy was FF 2,566,111 (1992) and the marginal effectiveness was 180 additional infected donations detected. The sensitivity analysis showed the major influence of infection prevalence in donated blood on the incremental cost-effectiveness ratio: the lower the prevalence, the higher the cost-effectiveness ratio per contaminated blood product avoided.

  4. Invasive non-native plants have a greater effect on neighbouring natives than other non-natives.

    PubMed

    Kuebbing, Sara E; Nuñez, Martin A

    2016-09-12

    Human activity is creating a global footprint by changing the climate, altering habitats and reshuffling the distribution of species. The movement of species around the globe has led to the naturalization and accumulation of multiple non-native species within ecosystems, which is frequently associated with habitat disturbance and changing environmental conditions. However, interactions among species will also influence community composition, but little is known about the full range of direct and indirect interactions among native and non-native species. Here, we show through a meta-analysis of 1,215 pairwise plant interactions between 274 vascular plant species in 21 major habitat types that interactions between non-native plants are asymmetrical with interactions between non-native and native plants. Non-native plants were always bad neighbours, but the negative effect of non-natives on natives was around two times greater than the effect of non-natives on other non-natives. In contrast, the performance of non-native plants was five times higher in the presence of a neighbouring native plant species than in the presence of a neighbouring non-native plant species. Together, these results demonstrate that invaded plant communities may accumulate additional non-native species even if direct interactions between non-natives species are negative. Put another way, invasions may be more likely to lead to more invasions, requiring more active management of ecosystems by promoting native species restoration to undermine invasive positive feedback and to assist native species recovery in invaded ecosystems.

  5. Resource theory of non-Gaussian operations

    NASA Astrophysics Data System (ADS)

    Zhuang, Quntao; Shor, Peter W.; Shapiro, Jeffrey H.

    2018-05-01

    Non-Gaussian states and operations are crucial for various continuous-variable quantum information processing tasks. To quantitatively understand non-Gaussianity beyond states, we establish a resource theory for non-Gaussian operations. In our framework, we consider Gaussian operations as free operations, and non-Gaussian operations as resources. We define entanglement-assisted non-Gaussianity generating power and show that it is a monotone that is nonincreasing under the set of free superoperations, i.e., concatenation and tensoring with Gaussian channels. For conditional unitary maps, this monotone can be analytically calculated. As examples, we show that the non-Gaussianity of ideal photon-number subtraction and photon-number addition equal the non-Gaussianity of the single-photon Fock state. Based on our non-Gaussianity monotone, we divide non-Gaussian operations into two classes: (i) the finite non-Gaussianity class, e.g., photon-number subtraction, photon-number addition, and all Gaussian-dilatable non-Gaussian channels; and (ii) the diverging non-Gaussianity class, e.g., the binary phase-shift channel and the Kerr nonlinearity. This classification also implies that not all non-Gaussian channels are exactly Gaussian dilatable. Our resource theory enables a quantitative characterization and a first classification of non-Gaussian operations, paving the way towards the full understanding of non-Gaussianity.

  6. 77 FR 67251 - Special Conditions: Boeing Model 757 Series Airplanes; Seats with Non-Traditional, Large, Non...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-09

    ..., large, non-metallic panels in their designs. In order to provide a level of safety that is equivalent to... with Non-Traditional, Large, Non-Metallic Panels AGENCY: Federal Aviation Administration (FAA), DOT... have novel or unusual design features associated with seats that include non-traditional, large, non...

  7. Non-Invasive Pneumothorax Detector

    DTIC Science & Technology

    2012-04-01

    AD_________________ Award Number: W81XWH-09-2-0092 TITLE: Non-Invasive Pneumothorax Detector...REPORT TYPE Final 3. DATES COVERED 27 July 2009 – 31 August 2011 4. TITLE AND SUBTITLE 5a. CONTRACT NUMBER Non-Invasive Pneumothorax ...that form the scope of work support the development and clinical testing of a non-invasive pneumothorax detector. Goal and objectives are reflected in

  8. 76 FR 6572 - Non-Ambulatory Disabled Veal Calves and Other Non-Ambulatory Disabled Livestock at Slaughter...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-07

    ... Service 9 CFR Part 309 [Docket No. FSIS-2010-0041] Non-Ambulatory Disabled Veal Calves and Other Non... the disposition of non-ambulatory disabled veal calves and other non-ambulatory disabled livestock at... after being warmed or rested. The HSUS has petitioned FSIS to amend the regulations to require that non...

  9. Dermatoscopic features of cutaneous non-facial non-acral lentiginous growth pattern melanomas

    PubMed Central

    Keir, Jeff

    2014-01-01

    Background: The dermatoscopic features of facial lentigo maligna (LM), facial lentigo maligna melanoma (LMM) and acral lentiginous melanoma (ALM) have been well described. This is the first description of the dermatoscopic appearance of a clinical series of cutaneous non-facial non-acral lentiginous growth pattern melanomas. Objective: To describe the dermatoscopic features of a series of cutaneous non-facial non-acral lentiginous growth pattern melanomas in an Australian skin cancer practice. Method: Single observer retrospective analysis of dermatoscopic images of a one-year series of cutaneous non-facial, non-acral melanomas reported as having a lentiginous growth pattern detected in an open access primary care skin cancer clinic in Australia. Lesions were scored for presence of classical criteria for facial LM; modified pattern analysis (“Chaos and Clues”) criteria; and the presence of two novel criteria: a lentigo-like pigment pattern lacking a lentigo-like border, and large polygons. Results: 20 melanomas occurring in 14 female and 6 male patients were included. Average patient age was 64 years (range: 44–83). Lesion distribution was: trunk 35%; upper limb 40%; and lower limb 25%. The incidences of criteria identified were: asymmetry of color or pattern (100%); lentigo-like pigment pattern lacking a lentigo-like border (90%); asymmetrically pigmented follicular openings (APFO’s) (70%); grey blue structures (70%); large polygons (45%); eccentric structureless area (15%); bright white lines (5%). 20% of the lesions had only the novel criteria and/or APFO’s. Limitations: Single observer, single center retrospective study. Conclusions: Cutaneous non-facial non-acral melanomas with a lentiginous growth pattern may have none or very few traditional criteria for the diagnosis of melanoma. Criteria that are logically expected in lesions with a lentiginous growth pattern (lentigo-like pigment pattern lacking a lentigo-like border, APFO’s) and the novel

  10. Dermatoscopic features of cutaneous non-facial non-acral lentiginous growth pattern melanomas.

    PubMed

    Keir, Jeff

    2014-01-01

    The dermatoscopic features of facial lentigo maligna (LM), facial lentigo maligna melanoma (LMM) and acral lentiginous melanoma (ALM) have been well described. This is the first description of the dermatoscopic appearance of a clinical series of cutaneous non-facial non-acral lentiginous growth pattern melanomas. To describe the dermatoscopic features of a series of cutaneous non-facial non-acral lentiginous growth pattern melanomas in an Australian skin cancer practice. Single observer retrospective analysis of dermatoscopic images of a one-year series of cutaneous non-facial, non-acral melanomas reported as having a lentiginous growth pattern detected in an open access primary care skin cancer clinic in Australia. Lesions were scored for presence of classical criteria for facial LM; modified pattern analysis ("Chaos and Clues") criteria; and the presence of two novel criteria: a lentigo-like pigment pattern lacking a lentigo-like border, and large polygons. 20 melanomas occurring in 14 female and 6 male patients were included. Average patient age was 64 years (range: 44-83). Lesion distribution was: trunk 35%; upper limb 40%; and lower limb 25%. The incidences of criteria identified were: asymmetry of color or pattern (100%); lentigo-like pigment pattern lacking a lentigo-like border (90%); asymmetrically pigmented follicular openings (APFO's) (70%); grey blue structures (70%); large polygons (45%); eccentric structureless area (15%); bright white lines (5%). 20% of the lesions had only the novel criteria and/or APFO's. Single observer, single center retrospective study. Cutaneous non-facial non-acral melanomas with a lentiginous growth pattern may have none or very few traditional criteria for the diagnosis of melanoma. Criteria that are logically expected in lesions with a lentiginous growth pattern (lentigo-like pigment pattern lacking a lentigo-like border, APFO's) and the novel criterion of large polygons may be useful in increasing sensitivity and

  11. 47 CFR 25.260 - Time sharing between DoD meteorological satellite systems and non-voice, non-geostationary...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... satellite systems and non-voice, non-geostationary satellite systems in the 400.15-401 MHz band. 25.260... systems and non-voice, non-geostationary satellite systems in the 400.15-401 MHz band. (a) A non-voice, non-geostationary mobile-satellite service system licensee (“NVNG licensee”) time-sharing spectrum in...

  12. 47 CFR 25.260 - Time sharing between DoD meteorological satellite systems and non-voice, non-geostationary...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... satellite systems and non-voice, non-geostationary satellite systems in the 400.15-401 MHz band. 25.260... systems and non-voice, non-geostationary satellite systems in the 400.15-401 MHz band. (a) A non-voice, non-geostationary mobile-satellite service system licensee (“NVNG licensee”) time-sharing spectrum in...

  13. 47 CFR 25.260 - Time sharing between DoD meteorological satellite systems and non-voice, non-geostationary...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... satellite systems and non-voice, non-geostationary satellite systems in the 400.15-401 MHz band. 25.260... systems and non-voice, non-geostationary satellite systems in the 400.15-401 MHz band. (a) A non-voice, non-geostationary mobile-satellite service system licensee (“NVNG licensee”) time-sharing spectrum in...

  14. 47 CFR 25.260 - Time sharing between DoD meteorological satellite systems and non-voice, non-geostationary...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... satellite systems and non-voice, non-geostationary satellite systems in the 400.15-401 MHz band. 25.260... systems and non-voice, non-geostationary satellite systems in the 400.15-401 MHz band. (a) The space stations of a non-voice, non-geostationary Mobile-Satellite Service (NVNG MSS) system time-sharing downlink...

  15. 47 CFR 25.260 - Time sharing between DoD meteorological satellite systems and non-voice, non-geostationary...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... satellite systems and non-voice, non-geostationary satellite systems in the 400.15-401 MHz band. 25.260... systems and non-voice, non-geostationary satellite systems in the 400.15-401 MHz band. (a) The space stations of a non-voice, non-geostationary Mobile-Satellite Service (NVNG MSS) system time-sharing downlink...

  16. Detection of transfusion-associated hepatitis caused by non-A, non-B, non-C flavivirus.

    PubMed

    Takács, M; Berencsi, G; Mezey, I; Brojnás, J; Barcsay, E; Garamvölgyi, E; Hütter, E; Ferenczi, E; Pipirász, E; Hollós, I

    1994-01-01

    Sera of patients suffering from acute hepatitis, and different forms of chronic hepatitis were found to be reactive to reagents prepared from the yellow fever virus (YF) vaccine strain. Serum samples of 1974 patients were tested, and 133 of them were positive. Hepatitis C virus specific antibodies were absent from the majority of them. The frequency of antibodies to other flaviviruses (tick-borne encephalitis, West Nile) and hepatitis B virus markers was similar to that measured among the population in Hungary positive for any of the surrogate markers of hepatitis infections. Results of both immunofluorescence tests, and Western blots suggest that there is a non-A, non-B, non-C hepatitis virus circulating among the Hungarian population, which possesses antigenic cross-reactivity with the yellow fever virus, but the identity to any of the known flaviviruses could not be verified yet. No history of yellow fever vaccination could be revealed in any of the patients included into this study. The anamnestic data on previous transfusions or surgical operations can be verified only in the case of the half of YFV-positive patients, nevertheless, the sexual transmission seems to be very infrequent. Attempts are continued in order to detect the viral RNA using polymerase chain reaction, and clone cDNA sequences for sequence analysis.

  17. Non-Commutative Rational Yang-Baxter Maps

    NASA Astrophysics Data System (ADS)

    Doliwa, Adam

    2014-03-01

    Starting from multidimensional consistency of non-commutative lattice-modified Gel'fand-Dikii systems, we present the corresponding solutions of the functional (set-theoretic) Yang-Baxter equation, which are non-commutative versions of the maps arising from geometric crystals. Our approach works under additional condition of centrality of certain products of non-commuting variables. Then we apply such a restriction on the level of the Gel'fand-Dikii systems what allows to obtain non-autonomous (but with central non-autonomous factors) versions of the equations. In particular, we recover known non-commutative version of Hirota's lattice sine-Gordon equation, and we present an integrable non-commutative and non-autonomous lattice modified Boussinesq equation.

  18. Educational Non-Philosophy

    ERIC Educational Resources Information Center

    Cole, David R.

    2015-01-01

    The final lines of Deleuze and Guattari's What is Philosophy? call for a non-philosophy to balance and act as a counterweight to the task of philosophy that had been described by them in terms of concept creation. In a footnote, Deleuze and Guattari mention François Laruelle's project of non-philosophy, but dispute its efficacy in terms of the…

  19. Ecological impacts of non-native species

    USGS Publications Warehouse

    Wilkinson, John W.

    2012-01-01

    Non-native species are considered one of the greatest threats to freshwater biodiversity worldwide (Drake et al. 1989; Allen and Flecker 1993; Dudgeon et al. 2005). Some of the first hypotheses proposed to explain global patterns of amphibian declines included the effects of non-native species (Barinaga 1990; Blaustein and Wake 1990; Wake and Morowitz 1991). Evidence for the impact of non-native species on amphibians stems (1) from correlative research that relates the distribution or abundance of a species to that of a putative non-native species, and (2) from experimental tests of the effects of a non-native species on survival, growth, development or behaviour of a target species (Kats and Ferrer 2003). Over the past two decades, research on the effects of non-native species on amphibians has mostly focused on introduced aquatic predators, particularly fish. Recent research has shifted to more complex ecological relationships such as influences of sub-lethal stressors (e.g. contaminants) on the effects of non-native species (Linder et al. 2003; Sih et al. 2004), non-native species as vectors of disease (Daszak et al. 2004; Garner et al. 2006), hybridization between non-natives and native congeners (Riley et al. 2003; Storfer et al. 2004), and the alteration of food-webs by non-native species (Nystrom et al. 2001). Other research has examined the interaction of non-native species in terms of facilitation (i.e. one non-native enabling another to become established or spread) or the synergistic effects of multiple non-native species on native amphibians, the so-called invasional meltdown hypothesis (Simerloff and Von Holle 1999). Although there is evidence that some non-native species may interact (Ricciardi 2001), there has yet to be convincing evidence that such interactions have led to an accelerated increase in the number of non-native species and cumulative impacts are still uncertain (Simberloff 2006). Applied research on the control, eradication, and

  20. Non-fatal Occupational Injuries among Non-governmental Employees in Malaysia

    PubMed Central

    ABAS, ADINEGARA BIN LUTFI; SAID, ABDUL RAZZAK BIN MOHD; MOHAMMED, MOHAMMED AZMAN BIN AZIZ; SATHIAKUMAR, NALINI

    2011-01-01

    We analyzed data on non-fatal occupational injuries reported to Malaysia’s social security organization from 2002 to 2006. There was a decrease in both the absolute number and the incidence rates of these injuries over time. About 40% of cases occurred in the manufacturing sector followed by the service (17%) and trading (17%) sectors. The agriculture sector reported the highest incidence rate (24.1/1,000), followed by the manufacturing sector subcategories of wood-product manufacturing (22.1/1,000) and non-metallic industries (20.8/1,000). Men age 40 to 59 and persons of Indian ethnicity had a greater tendency to sustain injuries. Government and non-governmental organizations should strive to develop strategies to reduce the occupational injuries targeting vulnerable groups. Enforcement of safety measures will further play an important role to ensure that both employees and employers take special precautions to address workplace hazards. PMID:21344818

  1. Non-fatal occupational injuries among non-governmental employees in Malaysia.

    PubMed

    Abas, Adinegara Bin Lutfi; Said, Abdul Razzak Bin Mohd; Mohammed, Mohammed Azman Bin Aziz; Sathiakumar, Nalini

    2011-01-01

    We analyzed data on non-fatal occupational injuries reported to Malaysia's social security organization from 2002 to 2006. There was a decrease in both the absolute number and the incidence rates of these injuries over time. About 40% of cases occurred in the manufacturing sector followed by the service (17%) and trading (17%) sectors. The agriculture sector reported the highest incidence rate (24.1/1,000), followed by the manufacturing sector subcategories of wood-product manufacturing (22.1/1,000) and non-metallic industries (20.8/1,000). Men age 40 to 59 and persons of Indian ethnicity had a greater tendency to sustain injuries. Government and non-governmental organizations should strive to develop strategies to reduce the occupational injuries targeting vulnerable groups. Enforcement of safety measures will further play an important role to ensure that both employees and employers take special precautions to address workplace hazards.

  2. The Cairo conference: feminists vs. the Pope.

    PubMed

    Grant, L

    1994-07-01

    The draft Programme of Action to be discussed at the UN International Conference on Population and Development (ICPD) in Cairo is not about population and development, but about women and related agendas, supporting the various family forms (which promote population growth), and incalculable amounts of funding to increase the breadth of goals (e.g., more funding to improve the quality of life in cities). It does little to link those goals with global population growth. The US Department of State supports the militant feminists' agenda, which is for money to be directed to women's advancement activities rather than to direct population programs. Their reasoning is that women will achieve the socially desirable fertility level if they have unimpeded freedom of choice. The Vatican, which opposes birth control and abortion, is chastising the women's groups and the population movement. The US government has shifted its position to accommodate the militant feminists. It is not listening to bioscientists, demographers, and others who might have mellowed the advocacy approach. The draft Programme of Action has no population goals, which are needed to operate a population program. The US government should call for meeting unmet needs for contraception, expansion of family planning facilities and services in developing countries, and reinstatement of goals in the international population dialogue. It should also continue efforts to persuade developing country leaders of the importance of the population issue and of incentives and disincentives. Its first priority should be population, followed by development assistance to maternal and child health services coordinated with family planning services.

  3. Use of a Non-Navigational, Non-Verbal Landmark Task in Children

    ERIC Educational Resources Information Center

    Overman, William; Pierce, Allison; Watterson, Lucas; Coleman, Jennifer K.

    2013-01-01

    Two hundred and twenty two children (104 females), 1-8 years of age and young adults, were tested for up to 25 days on five versions of a non-verbal, non-navigational landmark task that had previously been used for monkeys. In monkeys, performance on this task is severely impaired following damage to the parietal cortex. For the basic task, the…

  4. Non-volatile fatty acids in the diagnosis of non-specific vaginitis.

    PubMed Central

    Ison, C A; Easmon, C S; Dawson, S G; Southerton, G; Harris, J W

    1983-01-01

    In the vaginal washings of 100 women with symptomatic non-specific vaginitis a succinate/lactate ratio of greater than or equal to 0.4 had a diagnostic sensitivity of 80%, a specificity of 83% for this condition. The predictive value of a positive test was 94%, but that of a negative test was only 55%. A strong association between the presence of Gardnerella vaginalis, anaerobes, a vaginal pH of above 4.5, and amines was found not only in non-specific vaginitis, but also in trichomonal and gonococcal infection. A variety of primary changes may encourage the multiplication of both gardnerellae and anaerobes and their presence in non-specific vaginitis may be a secondary rather than a primary event. PMID:6606653

  5. Non-Cardiac Chest Pain

    MedlinePlus

    ... Home / Digestive Health Topic / Non-cardiac Chest Pain Non-cardiac Chest Pain Basics Overview and Symptoms What ... at a reduced dose such as Omeprazole (or equivalent PPI medication ) 20 mg twice daily about 40 ...

  6. Theory of Metastable State Relaxation for Non-Critical Binary Systems with Non-Conserved Order Parameter

    NASA Technical Reports Server (NTRS)

    Izmailov, Alexander; Myerson, Allan S.

    1993-01-01

    A new mathematical ansatz for a solution of the time-dependent Ginzburg-Landau non-linear partial differential equation is developed for non-critical systems such as non-critical binary solutions (solute + solvent) described by the non-conserved scalar order parameter. It is demonstrated that in such systems metastability initiates heterogeneous solute redistribution which results in formation of the non-equilibrium singly-periodic spatial solute structure. It is found how the time-dependent period of this structure evolves in time. In addition, the critical radius r(sub c) for solute embryo of the new solute rich phase together with the metastable state lifetime t(sub c) are determined analytically and analyzed.

  7. Non-Abelian statistics of vortices with non-Abelian Dirac fermions.

    PubMed

    Yasui, Shigehiro; Hirono, Yuji; Itakura, Kazunori; Nitta, Muneto

    2013-05-01

    We extend our previous analysis on the exchange statistics of vortices having a single Dirac fermion trapped in each core to the case where vortices trap two Dirac fermions with U(2) symmetry. Such a system of vortices with non-Abelian Dirac fermions appears in color superconductors at extremely high densities and in supersymmetric QCD. We show that the exchange of two vortices having doublet Dirac fermions in each core is expressed by non-Abelian representations of a braid group, which is explicitly verified in the matrix representation of the exchange operators when the number of vortices is up to four. We find that the result contains the matrices previously obtained for the vortices with a single Dirac fermion in each core as a special case. The whole braid group does not immediately imply non-Abelian statistics of identical particles because it also contains exchanges between vortices with different numbers of Dirac fermions. However, we find that it does contain, as its subgroup, genuine non-Abelian statistics for the exchange of the identical particles, that is, vortices with the same number of Dirac fermions. This result is surprising compared with conventional understanding because all Dirac fermions are defined locally at each vortex, unlike the case of Majorana fermions for which Dirac fermions are defined nonlocally by Majorana fermions located at two spatially separated vortices.

  8. Non-Gaussian quantum states generation and robust quantum non-Gaussianity via squeezing field

    NASA Astrophysics Data System (ADS)

    Tang, Xu-Bing; Gao, Fang; Wang, Yao-Xiong; Kuang, Sen; Shuang, Feng

    2015-03-01

    Recent studies show that quantum non-Gaussian states or using non-Gaussian operations can improve entanglement distillation, quantum swapping, teleportation, and cloning. In this work, employing a strategy of non-Gaussian operations (namely subtracting and adding a single photon), we propose a scheme to generate non-Gaussian quantum states named single-photon-added and -subtracted coherent (SPASC) superposition states by implementing Bell measurements, and then investigate the corresponding nonclassical features. By squeezed the input field, we demonstrate that robustness of non-Gaussianity can be improved. Controllable phase space distribution offers the possibility to approximately generate a displaced coherent superposition states (DCSS). The fidelity can reach up to F ≥ 0.98 and F ≥ 0.90 for size of amplitude z = 1.53 and 2.36, respectively. Project supported by the National Natural Science Foundation of China (Grant Nos. 61203061 and 61074052), the Outstanding Young Talent Foundation of Anhui Province, China (Grant No. 2012SQRL040), and the Natural Science Foundation of Anhui Province, China (Grant No. KJ2012Z035).

  9. Cancer Survival Estimates Due to Non-Uniform Loss to Follow-Up and Non-Proportional Hazards

    PubMed

    K M, Jagathnath Krishna; Mathew, Aleyamma; Sara George, Preethi

    2017-06-25

    Background: Cancer survival depends on loss to follow-up (LFU) and non-proportional hazards (non-PH). If LFU is high, survival will be over-estimated. If hazard is non-PH, rank tests will provide biased inference and Cox-model will provide biased hazard-ratio. We assessed the bias due to LFU and non-PH factor in cancer survival and provided alternate methods for unbiased inference and hazard-ratio. Materials and Methods: Kaplan-Meier survival were plotted using a realistic breast cancer (BC) data-set, with >40%, 5-year LFU and compared it using another BC data-set with <15%, 5-year LFU to assess the bias in survival due to high LFU. Age at diagnosis of the latter data set was used to illustrate the bias due to a non-PH factor. Log-rank test was employed to assess the bias in p-value and Cox-model was used to assess the bias in hazard-ratio for the non-PH factor. Schoenfeld statistic was used to test the non-PH of age. For the non-PH factor, we employed Renyi statistic for inference and time dependent Cox-model for hazard-ratio. Results: Five-year BC survival was 69% (SE: 1.1%) vs. 90% (SE: 0.7%) for data with low vs. high LFU respectively. Age (<45, 46-54 & >54 years) was a non-PH factor (p-value: 0.036). However, survival by age was significant (log-rank p-value: 0.026), but not significant using Renyi statistic (p=0.067). Hazard ratio (HR) for age using Cox-model was 1.012 (95%CI: 1.004 -1.019) and the same using time-dependent Cox-model was in the other direction (HR: 0.997; 95% CI: 0.997- 0.998). Conclusion: Over-estimated survival was observed for cancer with high LFU. Log-rank statistic and Cox-model provided biased results for non-PH factor. For data with non-PH factors, Renyi statistic and time dependent Cox-model can be used as alternate methods to obtain unbiased inference and estimates. Creative Commons Attribution License

  10. Non-Disclosure of HIV Status and Associations with Psychological Factors, ART Non-Adherence, and Viral Load Non-Suppression Among People Living with HIV in the UK.

    PubMed

    Daskalopoulou, Marina; Lampe, Fiona C; Sherr, Lorraine; Phillips, Andrew N; Johnson, Margaret A; Gilson, Richard; Perry, Nicky; Wilkins, Ed; Lascar, Monica; Collins, Simon; Hart, Graham; Speakman, Andrew; Rodger, Alison J

    2017-01-01

    Disclosure of HIV status to family, friends, and a stable partner may be linked to improved health outcomes for people living with HIV. This study assessed whether non-disclosure is associated with psychological symptoms, non-adherence to antiretroviral therapy (ART), and viral load (VL) non-suppression. A total of 3258 HIV-diagnosed individuals in the UK completed the confidential ASTRA study questionnaire (2011-2012). Participants reported whether they told anyone they had HIV; to which confidant(s) (friends, family, work colleagues, stable partner) and to what extent (none, some, most/all). The prevalence and factors associated with non-disclosure were assessed. Associations between non-disclosure and the following factors were established using modified Poisson regression with adjustment for socio-demographic factors (gender, age group, ethnicity), HIV-related factors (time since HIV diagnosis, ART status), and clinic: low social support (score ≤ 12 on modified Duke-UNC FSSQ); depression and anxiety symptoms (≥10 on PHQ-9 and GAD-7 respectively); self-reported ART non-adherence in past 2 weeks/3 months; VL non-suppression (clinic-recorded VL > 50 copies/mL among those who started ART ≥ 6 months ago). Among 3233 participants with disclosure data, the prevalence of non-disclosure to anyone was 16.6 % (n/N = 61/367) among heterosexual men, 15.7 % (98/626) among women, and 5.0 % (113/2240) among MSM. MSM were more likely to disclose to some/all friends compared to family (85.8 vs. 59.9 %) while heterosexuals were less likely to disclose to friends than family (44.1 vs. 61.1 % for men, 57.5 vs. 67.1 % for women). Among 1,631 participants with a stable partner, non-disclosure to a stable partner was 4.9 % for MSM, 10.9 % for heterosexual men, and 13.0 % for women. In adjusted analyses, older age (≥60 years), non-white ethnicity, more recent HIV diagnosis, and not having a stable partner were significantly associated with overall non

  11. Genetic Localization and Molecular Characterization of the nonS Gene Required for Macrotetrolide Biosynthesis in Streptomyces griseus DSM40695

    PubMed Central

    Smith, Wyatt C.; Xiang, Longkuan; Shen, Ben

    2000-01-01

    The macrotetrolides are a family of cyclic polyethers derived from tetramerization, in a stereospecific fashion, of the enantiomeric nonactic acid (NA) and its homologs. Isotope labeling experiments established that NA is of polyketide origin, and biochemical investigations demonstrated that 2-methyl-6,8-dihydroxynon-2E-enoic acid can be converted into NA by a cell-free preparation from Streptomyces lividans that expresses nonS. These results lead to the hypothesis that macrotetrolide biosynthesis involves a pair of enantiospecific polyketide pathways. In this work, a 55-kb contiguous DNA region was cloned from Streptomyces griseus DSM40695, a 6.3-kb fragment of which was sequenced to reveal five open reading frames, including the previously reported nonR and nonS genes. Inactivation of nonS in vivo completely abolished macrotetrolide production. Complementation of the nonS mutant by the expression of nonS in trans fully restored its macrotetrolide production ability, with a distribution of individual macrotetrolides similar to that for the wild-type producer. In contrast, fermentation of the nonS mutant in the presence of exogenous (±)-NA resulted in the production of nonactin, monactin, and dinactin but not in the production of trinactin and tetranactin. These results prove the direct involvement of nonS in macrotetrolide biosynthesis. The difference in macrotetrolide production between in vivo complementation of the nonS mutant by the plasmid-borne nonS gene and fermentation of the nonS mutant in the presence of exogenously added (±)-NA suggests that NonS catalyzes the formation of (−)-NA and its homologs, supporting the existence of a pair of enantiospecific polyketide pathways for macrotetrolide biosynthesis in S. griseus. The latter should provide a model that can be used to study the mechanism by which polyketide synthase controls stereochemistry during polyketide biosynthesis. PMID:10858335

  12. Understanding non ulcer dyspepsia.

    PubMed

    Loh, K Y; Siang, T K

    2008-06-01

    Non ulcer dyspepsia is one of the most common problems encountered in primary care practice. The underlying pathophysiology of non ulcer dyspepsia is not fully understood, but it is known that this condition is associated with H. pylori infection and motility disorder. The presenting abdominal symptoms are non specific: they include bloating, belching, flatulence, excessive fullness after eating and nausea. Psychological condition such as anxiety, depression and stress do play a role in the recurrence of symptoms. Upper GI endoscopy is necessary in patients who presents with alarm symptoms suggestive of possible underlying organic condition before one makes the diagnosis of non ulcer dyspepsia. Pharmacological therapy using H2 receptor antagonist and proton pump inhibitors are effective for symptom relief. Patient's education and supportive care should be part of the management strategy in recurrent chronic dyspepsia.

  13. (Non-)utilization of pre-hospital emergency care by migrants and non-migrants in Germany.

    PubMed

    Kietzmann, Diana; Knuth, Daniela; Schmidt, Silke

    2017-01-01

    This study was designed to explore the utilization and non-utilization of pre-hospital emergency care by migrants and non-migrants, and the factors that influence this behaviour. A cross-sectional representative German survey was conducted in a sample of 2.175 people, 295 of whom had a migration background. An additional sample of 50 people with Turkish migration background was conducted, partially in the Turkish language. Apart from socio-demographics, the utilization of emergency services and the reasons for non-utilization were assessed. Migrants had a higher utilization rate of pre-hospital emergency care (RR = 1.492) than non-migrants. Furthermore, migrants who were not born in Germany had a lower utilization rate (RR = 0.793) than migrants who were born in Germany. Regarding non-utilization, the most frequently stated reasons belonged to the categories initial misjudgment of the emergency situation and acting on one's own behalf, with the latter stated more frequently by migrants than by non-migrants. To prevent over-, under-, and lack of supply, it is necessary to transfer knowledge about the functioning of the medical emergency services, including first aid knowledge.

  14. Classification of non-union.

    PubMed

    Megas, Panagiotis; Panagiotis, Megas

    2005-11-01

    A substantial number of experimental and clinical studies have established that the cornerstones for successful bone-healing are biomechanical stability and biological vitality of the bone, as they both provide an environment in which new bone can be formed. Non-union of long bones is a significant consequence in treating fractures. Many approaches to prevent fracture non-union have been proposed. Depending on the type and location of the non-union, treatment options include various types of bone fixation, with or without supplemental bone graft or other biophysical enhancements.

  15. Non-manipulation quantitative designs.

    PubMed

    Rumrill, Phillip D

    2004-01-01

    The article describes non-manipulation quantitative designs of two types, correlational and causal comparative studies. Both of these designs are characterized by the absence of random assignment of research participants to conditions or groups and non-manipulation of the independent variable. Without random selection or manipulation of the independent variable, no attempt is made to draw causal inferences regarding relationships between independent and dependent variables. Nonetheless, non-manipulation studies play an important role in rehabilitation research, as described in this article. Examples from the contemporary rehabilitation literature are included. Copyright 2004 IOS Press

  16. La Moisissure et la Bactérie: Deconstructing the fable of the discovery of penicillin by Ernest Duchesne.

    PubMed

    Shama, Gilbert

    2016-09-01

    Ernest Duchesne (1874-1912) completed his thesis on microbial antagonism in 1897 in Lyon. His work lay unknown for fifty years, but on being brought to light led to his being credited with having discovered penicillin prior to Alexander Fleming. The claims surrounding Duchesne are examined here both from the strictly microbiological perspective, and also for what they reveal about how the process of discovery is frequently misconstrued. The combined weight of evidence presented here militates strongly against the possibility that the species of Penicillium that Duchesne worked with produced penicillin. Copyright © 2016 Elsevier Ltd. All rights reserved.

  17. Netz ohne doppelten Boden: Internet-Sicherheit

    NASA Astrophysics Data System (ADS)

    Fichtner, Johann

    2002-07-01

    Die Sicherheitslücken des heutigen Internets haben zwei Ursachen: sein ursprüngliches Design für rein militärische Zwecke sowie die gefährliche Sorglosigkeit der Entwickler und Betreiber von Internet-Komponenten. Dabei kann ein kleiner Kreis von Experten Angriffe auf die eigentlichen Netzknoten ausführen. Typische Hacker-Angriffe kommen von Endsystemen des Internets und richten sich auch gegen Endsysteme wie Firmen-Intranets oder einzelne PCs. Dagegen gibt es eine Reihe von Schutzmöglichkeiten. Es ist jedoch keine einfache Lösung zur Erhöhung der Internet-Sicherheit in Sicht.

  18. Current Treatment Algorithms for Patients with Metastatic Non-Small Cell, Non-Squamous Lung Cancer

    PubMed Central

    Melosky, Barbara

    2017-01-01

    The treatment paradigm for metastatic non-small cell, non-squamous lung cancer is continuously evolving due to new treatment options and our increasing knowledge of molecular signal pathways. As a result of treatments becoming more efficacious and more personalized, survival for selected groups of non-small cell lung cancer (NSCLC) patients is increasing. In this paper, three algorithms will be presented for treating patients with metastatic non-squamous, NSCLC. These include treatment algorithms for NSCLC patients whose tumors have EGFR mutations, ALK rearrangements, or wild-type/wild-type tumors. As the world of immunotherapy continues to evolve quickly, a future algorithm will also be presented. PMID:28373963

  19. On q-non-extensive statistics with non-Tsallisian entropy

    NASA Astrophysics Data System (ADS)

    Jizba, Petr; Korbel, Jan

    2016-02-01

    We combine an axiomatics of Rényi with the q-deformed version of Khinchin axioms to obtain a measure of information (i.e., entropy) which accounts both for systems with embedded self-similarity and non-extensivity. We show that the entropy thus obtained is uniquely solved in terms of a one-parameter family of information measures. The ensuing maximal-entropy distribution is phrased in terms of a special function known as the Lambert W-function. We analyze the corresponding "high" and "low-temperature" asymptotics and reveal a non-trivial structure of the parameter space. Salient issues such as concavity and Schur concavity of the new entropy are also discussed.

  20. Transient adhesion in a non-fully detached contact.

    PubMed

    Liu, Zheyu; Lu, Hongyu; Zheng, Yelong; Tao, Dashuai; Meng, Yonggang; Tian, Yu

    2018-04-18

    Continuous approaching and detaching displacement usually occurs in an adhesion test. Here, we found a transient adhesion force at the end of a non-fully detached contact. This force occurred when the nominal detaching displacement was less than the traditional quasi-static theory predicted zero force point. The transient adhesion force was ascribed to interfacial adhesion hysteresis, which was caused by the cracking process of the contact and the deformation competition between the sphere and supporting spring. Results indicated that the testing of adhesion can be significantly affected by different combinations of stiffnesses of the contact objects and the supporting spring cantilever. This combination should be carefully designed in an adhesion test. All these results enabled increased understanding of the nature of adhesion and can guide the design of adhesive actuators.

  1. Non-holonomic integrators

    NASA Astrophysics Data System (ADS)

    Cortés, J.; Martínez, S.

    2001-09-01

    We introduce a discretization of the Lagrange-d'Alembert principle for Lagrangian systems with non-holonomic constraints, which allows us to construct numerical integrators that approximate the continuous flow. We study the geometric invariance properties of the discrete flow which provide an explanation for the good performance of the proposed method. This is tested on two examples: a non-holonomic particle with a quadratic potential and a mobile robot with fixed orientation.

  2. Non-smoker assertive behaviour against smoke exposure: Chinese and Korean American non-smokers.

    PubMed

    Saw, Anne; Tang, Hao; Tsoh, Janice Y; Chen, Moon S; Tong, Elisa K

    2017-11-01

    Non-smokers' assertive behaviour towards smokers by asking them not to smoke is important in promoting smoke-free environments. Korean and Chinese Americans come from countries where most women are non-smokers and assertive behaviour may not be prevalent but may increase after migration because of social-ecological factors. This study assessed the extent to which Korean and Chinese American non-smokers ask someone not to smoke and associated factors. The 2003 California Chinese American and Korean American Tobacco Use Surveys were analysed. Multivariate logistic regression analyses examined factors related to non-smoker self-reports that they asked someone not to smoke within the past year. About 40% reported past-year assertive behaviour against smoking, with higher rates among Koreans than Chinese (60.4% vs. 34.5%), those living with smokers (63.5%), ever exposed with a smoke-free home rule (62.3%), recently exposed at work without a smoke-free work policy (67.6%) and regularly exposed at other locations (52.3%). In combined multivariate analyses of both ethnic groups, assertive behaviour was associated with individual factors (single vs. married; tobacco exposure knowledge), family factors (living with smokers, exposed at home despite a smoke-free rule), community factors (exposed at work with no smoke-free policy, exposed at other locations) and cultural factors (Korean vs. Chinese ethnicity; lower acculturation). Chinese and Korean American non-smokers report assertive behaviour against smoking, which is associated with social-ecological factors. Results help identify target groups and strategies for future intervention, including the need to implement or enforce smoke-free environments and promote empowerment. [Saw A, Tang H, Tsoh JY, Chen MS Jr, Tong EK. Non-smoker assertive behaviour against smoke exposure: Chinese and Korean American non-smokers. © 2017 Australasian Professional Society on Alcohol and other Drugs.

  3. Non-perturbative aspects of particle acceleration in non-linear electrodynamics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Burton, David A.; Flood, Stephen P.; Wen, Haibao

    2015-04-15

    We undertake an investigation of particle acceleration in the context of non-linear electrodynamics. We deduce the maximum energy that an electron can gain in a non-linear density wave in a magnetised plasma, and we show that an electron can “surf” a sufficiently intense Born-Infeld electromagnetic plane wave and be strongly accelerated by the wave. The first result is valid for a large class of physically reasonable modifications of the linear Maxwell equations, whilst the second result exploits the special mathematical structure of Born-Infeld theory.

  4. Reproductive autonomy, the non-identity problem, and the non-person problem.

    PubMed

    DiSilvestro, Russell

    2009-01-01

    The Non-Identity Problem is the problem of explaining the apparent wrongness of a decision that does not harm people, especially since some of the people affected by the decision would not exist at all were it not for the decision. One approach to this problem, in the context of reproductive decisions, is to focus on wronging, rather than harming, one's offspring. But a Non-Person Problem emerges for any view that claims (1) that only persons can be wronged and (2) that the person-making properties allow for there to be human non-persons. Consider an individual human organism that is prevented from ever possessing the person-making properties. On person-only accounts of the victims of wronging, this organism cannot be wronged by anyone. Hence even individuals whose decisions prevent it from ever possessing the person-making properties cannot wrong it. But this is counter-intuitive. We can think of examples where a human organism is wronged by precisely those decisions that prevent it from possessing the person-making properties. The best solution to this problem, in the case where the person-making property is rational self-governance in pursuit of a meaningful life, is to adjust the concept of a person so that it refers, not merely to those with the immediate capacity for rational self-governance in pursuit of a meaningful life, but also to those with a higher-order capacity for such self-governance. Any solution to the Non-Identity Problem that focuses on wronging rather than harming should incorporate this sort of solution to the Non-Person Problem.

  5. Risky Car Following in Abstinent Users of MDMA

    PubMed Central

    Dastrup, Elizabeth; Lees, Monica; Bechara, Antoine; Dawson, Jeffrey D.; Rizzo, Matthew

    2011-01-01

    Ecstasy (MDMA) use raises concerns because of its association with risky driving. We evaluated driving performance and risk taking in abstinent recreational MDMA users in a simulated car following task that required continuous attention and vigilance. Drivers were asked to follow two car lengths behind a lead vehicle (LV). Three sinusoids generated unpredictable LV velocity changes. Drivers could mitigate risk by following further behind the erratic LV. From vehicle trajectory data we performed a Fourier analysis to derive measures of coherence, gain, and delay. These measures and headway distance were compared between the different groups. All MDMA drivers met coherence criteria indicating cooperation in the car following task. They matched periodic changes in LV velocity similar to controls (abstinent THC users, abstinent alcohol users, and non-drug users), militating against worse vigilance. While all participants traveled approximately 55mph (89kph), the MDMA drivers followed 64m closer to the LV and demonstrated 1.04s shorter delays to LV velocity changes than other driver groups. The simulated car following task safely discriminated between driving behavior in abstinent MDMA users and controls. Abstinent MDMA users do not perform worse than controls, but may assume extra risk. The control theory framework used in this study revealed behaviors that might not otherwise be evident. PMID:20380914

  6. NON-POINT SOURCE POLLUTION

    EPA Science Inventory

    Non-point source pollution is a diffuse source that is difficult to measure and is highly variable due to different rain patterns and other climatic conditions. In many areas, however, non-point source pollution is the greatest source of water quality degradation. Presently, stat...

  7. 75 FR 32 - Special Conditions: Airbus Model A340 Series Airplanes; Seats With Non-Traditional, Large, Non...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-04

    ... incorporate non-traditional, large, non-metallic panels. To provide a level of safety that is equivalent to...; Special Conditions No. 25-399-SC] Special Conditions: Airbus Model A340 Series Airplanes; Seats With Non-Traditional, Large, Non-Metallic Panels AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final...

  8. Non-HFE haemochromatosis

    PubMed Central

    Wallace, Daniel F; Subramaniam, V Nathan

    2007-01-01

    Non-HFE hereditary haemochromatosis (HH) refers to a genetically heterogeneous group of iron overload disorders that are unlinked to mutations in the HFE gene. The four main types of non-HFE HH are caused by mutations in the hemojuvelin, hepcidin, transferrin receptor 2 and ferroportin genes. Juvenile haemochromatosis is an autosomal recessive disorder and can be caused by mutations in either hemojuvelin or hepcidin. An adult onset form of HH similar to HFE-HH is caused by homozygosity for mutations in transferrin receptor 2. The autosomal dominant iron overload disorder ferroportin disease is caused by mutations in the iron exporter ferroportin. The clinical characteristics and molecular basis of the various types of non-HFE haemochromatosis are reviewed. The study of these disorders and the molecules involved has been invaluable in improving our understanding of the mechanisms involved in the regulation of iron metabolism. PMID:17729390

  9. Non-Abelian gauge preheating

    NASA Astrophysics Data System (ADS)

    Adshead, Peter; Giblin, John T.; Weiner, Zachary J.

    2017-12-01

    We study preheating in models where a scalar inflaton is directly coupled to a non-Abelian S U (2 ) gauge field. In particular, we examine m2ϕ2 inflation with a conformal, dilatonlike coupling to the non-Abelian sector. We describe a numerical scheme that combines lattice gauge theory with standard finite difference methods applied to the scalar field. We show that a significant tachyonic instability allows for efficient preheating, which is parametrically suppressed by increasing the non-Abelian self-coupling. Additionally, we comment on the technical implementation of the evolution scheme and setting initial conditions.

  10. [Reflections about non compliance].

    PubMed

    Consoli, S G

    2012-01-01

    Throughout the follow up of a patient suffering from a chronic cutaneous disease, non compliance is rarely avoidable. It is provoked by numerous factors, which have to be looked for in the patient and the doctor, as well, and in the external reality, as in the internal, psychic, reality, both of the patient and the doctor. Being aware of these factors is fundamental for resolving the non compliance conflict. Thus, non compliance can become a chance to seize for avoiding patients' wandering and building a more dynamic, authentic and stronger doctor-patient relationship. Copyright © 2012 Elsevier Masson SAS. All rights reserved.

  11. 40 CFR 26.1704 - Prohibition of reliance on unethical human research with non-pregnant, non-nursing adults...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Prohibition of reliance on unethical human research with non-pregnant, non-nursing adults conducted before April 7, 2006. 26.1704 Section 26... Prohibition of reliance on unethical human research with non-pregnant, non-nursing adults conducted before...

  12. 40 CFR 26.1705 - Prohibition of reliance on unethical human research with non-pregnant, non-nursing adults...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 1 2014-07-01 2014-07-01 false Prohibition of reliance on unethical human research with non-pregnant, non-nursing adults initiated after April 7, 2006. 26.1705 Section 26... Prohibition of reliance on unethical human research with non-pregnant, non-nursing adults initiated after...

  13. 40 CFR 26.1704 - Prohibition of reliance on unethical human research with non-pregnant, non-nursing adults...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Prohibition of reliance on unethical human research with non-pregnant, non-nursing adults conducted before April 7, 2006. 26.1704 Section 26... Prohibition of reliance on unethical human research with non-pregnant, non-nursing adults conducted before...

  14. 40 CFR 26.1705 - Prohibition of reliance on unethical human research with non-pregnant, non-nursing adults...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 1 2013-07-01 2013-07-01 false Prohibition of reliance on unethical human research with non-pregnant, non-nursing adults initiated after April 7, 2006. 26.1705 Section 26... Prohibition of reliance on unethical human research with non-pregnant, non-nursing adults initiated after...

  15. 40 CFR 26.1705 - Prohibition of reliance on unethical human research with non-pregnant, non-nursing adults...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 1 2012-07-01 2012-07-01 false Prohibition of reliance on unethical human research with non-pregnant, non-nursing adults conducted after April 7, 2006. 26.1705 Section 26... Prohibition of reliance on unethical human research with non-pregnant, non-nursing adults conducted after...

  16. 40 CFR 26.1705 - Prohibition of reliance on unethical human research with non-pregnant, non-nursing adults...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Prohibition of reliance on unethical human research with non-pregnant, non-nursing adults conducted after April 7, 2006. 26.1705 Section 26... Prohibition of reliance on unethical human research with non-pregnant, non-nursing adults conducted after...

  17. 40 CFR 26.1705 - Prohibition of reliance on unethical human research with non-pregnant, non-nursing adults...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Prohibition of reliance on unethical human research with non-pregnant, non-nursing adults conducted after April 7, 2006. 26.1705 Section 26... Prohibition of reliance on unethical human research with non-pregnant, non-nursing adults conducted after...

  18. 40 CFR 26.1704 - Prohibition of reliance on unethical human research with non-pregnant, non-nursing adults...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 1 2012-07-01 2012-07-01 false Prohibition of reliance on unethical human research with non-pregnant, non-nursing adults conducted before April 7, 2006. 26.1704 Section 26... Prohibition of reliance on unethical human research with non-pregnant, non-nursing adults conducted before...

  19. 40 CFR 26.1704 - Prohibition of reliance on unethical human research with non-pregnant, non-nursing adults.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 1 2013-07-01 2013-07-01 false Prohibition of reliance on unethical human research with non-pregnant, non-nursing adults. 26.1704 Section 26.1704 Protection of Environment... research with non-pregnant, non-nursing adults. (a) This section applies to research subject to this...

  20. 40 CFR 26.1704 - Prohibition of reliance on unethical human research with non-pregnant, non-nursing adults.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 1 2014-07-01 2014-07-01 false Prohibition of reliance on unethical human research with non-pregnant, non-nursing adults. 26.1704 Section 26.1704 Protection of Environment... research with non-pregnant, non-nursing adults. (a) This section applies to research subject to this...

  1. 45 CFR 98.91 - Non-compliance.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 1 2011-10-01 2011-10-01 false Non-compliance. 98.91 Section 98.91 Public Welfare..., Non-compliance and Complaints § 98.91 Non-compliance. (a) If after reasonable notice to a Lead Agency... the Lead Agency a written notice of a finding of non-compliance. This notice will be issued within 60...

  2. Psychiatric Problems and Trauma Exposure in Non-detained Delinquent and Non-delinquent Adolescents

    PubMed Central

    Adams, Zachary W.; McCart, Michael R.; Zajac, Kristyn; Danielson, Carla Kmett; Sawyer, Genelle K.; Saunders, Benjamin E.; Kilpatrick, Dean G.

    2014-01-01

    Objective This study examined the prevalence of and associations between specific psychiatric disorders, substance use problems, and trauma exposure in a sample of delinquent and non-delinquent adolescents. Method A nationally representative sample of adolescents (n = 3,614; mean age = 14.5 years, SD = 1.7; 51% male; 71% White, non-Hispanic, 13.3% African American, non-Hispanic, 10.7% Hispanic) was interviewed via telephone about engagement in delinquent acts and their experience of posttraumatic stress disorder, major depressive episode, substance use, interpersonal violence, and other forms of trauma exposure. Results Delinquent adolescents were more likely than non-delinquent adolescents to experience trauma; they were also more likely to report past-year posttraumatic stress disorder, major depressive episode, alcohol abuse, and non-experimental drug use. After accounting for the effects of demographics and trauma exposure, delinquency was associated with increased likelihood of posttraumatic stress disorder and problematic substance use in both genders and increased likelihood of major depressive episode in girls. Conclusions Findings highlight substantial overlap among delinquency, trauma exposure, posttraumatic stress disorder, and major depressive episode in adolescents and the need for interventions that address these varied clinical problems. Future work should examine the factors underlying the development of these relations over time. PMID:23236966

  3. Non-Hermitian bidirectional robust transport

    NASA Astrophysics Data System (ADS)

    Longhi, Stefano

    2017-01-01

    Transport of quantum or classical waves in open systems is known to be strongly affected by non-Hermitian terms that arise from an effective description of system-environment interaction. A simple and paradigmatic example of non-Hermitian transport, originally introduced by Hatano and Nelson two decades ago [N. Hatano and D. R. Nelson, Phys. Rev. Lett. 77, 570 (1996), 10.1103/PhysRevLett.77.570], is the hopping dynamics of a quantum particle on a one-dimensional tight-binding lattice in the presence of an imaginary vectorial potential. The imaginary gauge field can prevent Anderson localization via non-Hermitian delocalization, opening up a mobility region and realizing robust transport immune to disorder and backscattering. Like for robust transport of topologically protected edge states in quantum Hall and topological insulator systems, non-Hermitian robust transport in the Hatano-Nelson model is unidirectional. However, there is not any physical impediment to observe robust bidirectional non-Hermitian transport. Here it is shown that in a quasi-one-dimensional zigzag lattice, with non-Hermitian (imaginary) hopping amplitudes and a synthetic gauge field, robust transport immune to backscattering can occur bidirectionally along the lattice.

  4. Disintegration in Peru - Consolidation in Chile: The Case for Militant Capitalism in Latin America

    DTIC Science & Technology

    1990-06-01

    organization Comision Chilena de Derechos Humanos (CCDH), (which along with the Church-sponsored Vicaria de la Solaridad are the principal watchdog...34 reported by Chile’s human rights group Comision de Desechos Humanos (CCDH), the majority reflect a particular 134 period in time during which DINA was the

  5. [Characteristics of non-marital and non-commercial heterosexual transmission of HIV infection in Miao-Dong Autonomous prefecture of Qiandongnan].

    PubMed

    Yu, Q Y; Wang, F L; Xu, P; Wen, H J; Xiong, Y X; Yang, J; Long, Y; He, H J; Shi, J; Lyu, P

    2017-11-06

    Objective: The goal of this research was to understand the demographic distribution and related factors of non-marital and non-commercial heterosexual transmission (non-commercial transmission) for HIV/AIDS (human immunodeficiency virus/acquired immunodeficiency syndrome). Methods: Data related to HIV/AIDS infected by non-marital heterosexual transmission and whose present address was in Qian Dongnan, were collected from Information System on the HIV/AIDS Prevention and Control. Information included demographic characteristics, the members of non-marital sex partners, transmission path, detection source, CD4(+)T lymphocyte level, et al. cases belong to homosexual history, injective drug use or non-classified non-marital heterosexuality transmission were excluded, totally collect HIV/AIDS 919 cases. Multivariate logistic regressions were used to analyze potential factors associated with non-marital and non-commercial heterosexual transmission. In addition, in March and June 2017, using a convenience sampling, we conducted one-to-one interviews among 10 HIV/AIDS who were infected by non-marital heterosexuality and had non-marital and non-commercial heterosexual experience in Kaili Center for Disease Control and Prevention. The content of the interview included basic information, sexual orientation, the main place of making friends and sexual behavior, attitude to commercial heterosexuality and non-martial and non-commercial heterosexuality and so on. Results: Out of the 919 cases, 645 (70.2%) were male, the proportion of non-commercial transmission was 55.06% (506). The proportion of female HIV/AIDS with non-commercial transmission was 84.7% (232), which was higher than male (42.5%(274)) (χ(2)=138.35, P< 0.001). The proportion of Han HIV/AIDS with non-commercial transmission was 61.5% (275), which was higher than other religion (52.2%(412)) (χ(2)=6.32, P= 0.012). The proportion of HIV/AIDS with non-commercial transmission who had 0-5 non-marital sexual partners was

  6. Sparse non-negative matrix factorizations via alternating non-negativity-constrained least squares for microarray data analysis.

    PubMed

    Kim, Hyunsoo; Park, Haesun

    2007-06-15

    Many practical pattern recognition problems require non-negativity constraints. For example, pixels in digital images and chemical concentrations in bioinformatics are non-negative. Sparse non-negative matrix factorizations (NMFs) are useful when the degree of sparseness in the non-negative basis matrix or the non-negative coefficient matrix in an NMF needs to be controlled in approximating high-dimensional data in a lower dimensional space. In this article, we introduce a novel formulation of sparse NMF and show how the new formulation leads to a convergent sparse NMF algorithm via alternating non-negativity-constrained least squares. We apply our sparse NMF algorithm to cancer-class discovery and gene expression data analysis and offer biological analysis of the results obtained. Our experimental results illustrate that the proposed sparse NMF algorithm often achieves better clustering performance with shorter computing time compared to other existing NMF algorithms. The software is available as supplementary material.

  7. A review on prognostic techniques for non-stationary and non-linear rotating systems

    NASA Astrophysics Data System (ADS)

    Kan, Man Shan; Tan, Andy C. C.; Mathew, Joseph

    2015-10-01

    The field of prognostics has attracted significant interest from the research community in recent times. Prognostics enables the prediction of failures in machines resulting in benefits to plant operators such as shorter downtimes, higher operation reliability, reduced operations and maintenance cost, and more effective maintenance and logistics planning. Prognostic systems have been successfully deployed for the monitoring of relatively simple rotating machines. However, machines and associated systems today are increasingly complex. As such, there is an urgent need to develop prognostic techniques for such complex systems operating in the real world. This review paper focuses on prognostic techniques that can be applied to rotating machinery operating under non-linear and non-stationary conditions. The general concept of these techniques, the pros and cons of applying these methods, as well as their applications in the research field are discussed. Finally, the opportunities and challenges in implementing prognostic systems and developing effective techniques for monitoring machines operating under non-stationary and non-linear conditions are also discussed.

  8. [Non-verbal communication in Alzheimer's disease].

    PubMed

    Schiaratura, Loris Tamara

    2008-09-01

    This review underlines the importance of non-verbal communication in Alzheimer's disease. A social psychological perspective of communication is privileged. Non-verbal behaviors such as looks, head nods, hand gestures, body posture or facial expression provide a lot of information about interpersonal attitudes, behavioral intentions, and emotional experiences. Therefore they play an important role in the regulation of interaction between individuals. Non-verbal communication is effective in Alzheimer's disease even in the late stages. Patients still produce non-verbal signals and are responsive to others. Nevertheless, few studies have been devoted to the social factors influencing the non-verbal exchange. Misidentification and misinterpretation of behaviors may have negative consequences for the patients. Thus, improving the comprehension of and the response to non-verbal behavior would increase first the quality of the interaction, then the physical and psychological well-being of patients and that of caregivers. The role of non-verbal behavior in social interactions should be approached from an integrative and functional point of view.

  9. Output Tracking for Systems with Non-Hyperbolic and Near Non-Hyperbolic Internal Dynamics: Helicopter Hover Control

    NASA Technical Reports Server (NTRS)

    Devasia, Santosh

    1996-01-01

    A technique to achieve output tracking for nonminimum phase linear systems with non-hyperbolic and near non-hyperbolic internal dynamics is presented. This approach integrates stable inversion techniques, that achieve exact-tracking, with approximation techniques, that modify the internal dynamics to achieve desirable performance. Such modification of the internal dynamics is used (1) to remove non-hyperbolicity which an obstruction to applying stable inversion techniques and (2) to reduce large pre-actuation time needed to apply stable inversion for near non-hyperbolic cases. The method is applied to an example helicopter hover control problem with near non-hyperbolic internal dynamic for illustrating the trade-off between exact tracking and reduction of pre-actuation time.

  10. [Non-autoimmune thyroiditis].

    PubMed

    Rizzo, Leonardo F L; Mana, Daniela L; Bruno, Oscar D

    2014-01-01

    The term thyroiditis comprises a group of thyroid diseases characterized by the presence of inflammation, including autoimmune and non-autoimmune entities. It may manifest as an acute illness with severe thyroid pain (subacute thyroiditis and infectious thyroiditis), and conditions in which the inflammation is not clinically evident evolving without pain and presenting primarily thyroid dysfunction and/or goiter (drug-induced thyroiditis and Riedel thyroiditis). The aim of this review is to provide an updated approach on non-autoimmune thyroiditis and its clinical, diagnostic and therapeutic aspects.

  11. An anthology of non-local QFT and QFT on non-commutative spacetime

    NASA Astrophysics Data System (ADS)

    Schroer, Bert

    2005-09-01

    Ever since the appearance of renormalization theory, there have been several differently motivated attempts at non-localized (in the sense of not generated by pointlike fields) relativistic particle theories, the most recent one being at QFT on non-commutative Minkowski spacetime. The often conceptually uncritical and historically forgetful contemporary approach to these problems calls for a critical review in the light of previous results on this subject.

  12. 75 FR 39 - Special Conditions: Boeing Model 757 Series Airplanes; Seats With Non-Traditional, Large, Non...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-04

    ...-traditional, large, non-metallic panels in their designs. To provide a level of safety that is equivalent to...; Special Conditions No. 25-397-SC] Special Conditions: Boeing Model 757 Series Airplanes; Seats With Non-Traditional, Large, Non-Metallic Panels AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final...

  13. NON-SPECIFIC SYMPTOMS AND SCREENING OF NON-PSYCHOTIC MORBIDITY IN PRIMARY CARE1

    PubMed Central

    Srinivasan, T.N.; Suresh, T.R.

    1990-01-01

    SUMMARY Much of the non-psychotic mental morbidity in primary care goes undetected by the primary care health personnel. This is often because of the non-specific somatic nature of the presenting complaints of these patients and the difficulty on the part of the primary care physician to elicit specific emotional symptoms to screen psychiatric problems. This paper describes the development of the 7-item Primary care Psychiatric Questionnaire (PPQ.) which, by requiring to elicit only the non-specific symptoms, could overcome this practical difficulty. This new screening method has been standardised against the Self Report Questionaaire—20-item version which is commonly used in primary care. PMID:21927432

  14. The Non-Traditional Student.

    ERIC Educational Resources Information Center

    Ely, Eileen E.

    The non-traditional student, or adult learner, is making up the new majority in secondary education, creating several implications for community colleges. The average non-traditional student is an adult, age 25 or older, who has returned to school either full-time or part-time. The student must balance school with employment, family, and financial…

  15. Non-Serious Serious Games

    ERIC Educational Resources Information Center

    Hudson, Matthew

    2016-01-01

    Serious games have been shown to promote behavioural change and impart skills to players, and non-serious games have proven to have numerous benefits. This paper argues that non-serious digital games played in a "clan" or online community setting can lead to similar real world benefits to serious games. This paper reports the outcomes…

  16. Prevalence of non-food allergies among non-immigrants, long-time immigrants and recent immigrants in Canada.

    PubMed

    Yao, Jiayun; Sbihi, Hind

    2016-12-27

    The prevalence of allergic conditions has been increasing worldwide, with the highest rates seen in Western countries like Canada. The development of allergies is known to be related to both genetic and environmental factors, but the causal pathways remain unclear. Studies on immigrants provide a unique opportunity to disentangle these two factors and provide a better understanding of the disease aetiology. The aim of this study was to investigate the relationship between immigration status and prevalence of non-food allergies in a population-based study of Canadians. Data of 116,232 respondents from the Canadian Community Health Survey (Cycle 3.1, 2005) were used in a multivariable logistic regression to assess the association between immigration status (non-immigrant, long-time immigrant [>10 years] and recent immigrant [≤10 years]) and self-reported doctor-diagnosed non-food allergies, adjusting for potential confounders. The highest prevalence of non-food allergies was found among non-immigrants (29.6%), followed by long-time immigrants (23.9%) and then recent immigrants (14.3%). The odds of non-food allergies were reduced by 60% (OR = 0.40, 95% CI: 0.35, 0.45) among recent immigrants and 25% (OR = 0.75, 95% CI: 0.70, 0.80) among long-time immigrants, compared with non-immigrants, after adjusting for sex, age, socio-economic status and rurality. This study finds a distinctly lower prevalence of non-food allergies among immigrants compared with non-immigrants, with the difference diminishing with longer duration of residence in Canada. The findings highlight the potential of environmental determinants of allergy development that warrant further investigation, and demonstrate the need for multicultural strategies to manage the public health burden of allergic conditions.

  17. Non-functional Avionics Requirements

    NASA Astrophysics Data System (ADS)

    Paulitsch, Michael; Ruess, Harald; Sorea, Maria

    Embedded systems in aerospace become more and more integrated in order to reduce weight, volume/size, and power of hardware for more fuel-effi ciency. Such integration tendencies change architectural approaches of system ar chi tec tures, which subsequently change non-functional requirements for plat forms. This paper provides some insight into state-of-the-practice of non-func tional requirements for developing ultra-critical embedded systems in the aero space industry, including recent changes and trends. In particular, formal requi re ment capture and formal analysis of non-functional requirements of avionic systems - including hard-real time, fault-tolerance, reliability, and per for mance - are exemplified by means of recent developments in SAL and HiLiTE.

  18. Quantized Electromagnetic-Field Propagation in General Non-Local and Non-Stationary Dispersive and Absorbing Media

    NASA Astrophysics Data System (ADS)

    Jacobs, Verne

    Dynamical descriptions for the propagation of quantized electromagnetic fields, in the presence of environmental interactions, are systematically and self-consistently developed in the complimentary Schrödinger and Heisenberg pictures. An open-systems (non-equilibrium) quantum-electrodynamics description is thereby provided for electromagnetic-field propagation in general non-local and non-stationary dispersive and absorbing optical media, including a fundamental microscopic treatment of decoherence and relaxation processes due to environmental collisional and electromagnetic interactions. Particular interest is centered on entangled states and other non-classical states of electromagnetic fields, which may be created by non-linear electromagnetic interactions and detected by the measurement of various electromagnetic-field correlation functions. Accordingly, we present dynamical descriptions based on general forms of electromagnetic-field correlation functions involving both the electric-field and the magnetic-field components of the electromagnetic field, which are treated on an equal footing. Work supported by the Office of Naval Research through the Basic Research Program at The Naval Research Laboratory.

  19. Word Durations in Non-Native English

    PubMed Central

    Baker, Rachel E.; Baese-Berk, Melissa; Bonnasse-Gahot, Laurent; Kim, Midam; Van Engen, Kristin J.; Bradlow, Ann R.

    2010-01-01

    In this study, we compare the effects of English lexical features on word duration for native and non-native English speakers and for non-native speakers with different L1s and a range of L2 experience. We also examine whether non-native word durations lead to judgments of a stronger foreign accent. We measured word durations in English paragraphs read by 12 American English (AE), 20 Korean, and 20 Chinese speakers. We also had AE listeners rate the `accentedness' of these non-native speakers. AE speech had shorter durations, greater within-speaker word duration variance, greater reduction of function words, and less between-speaker variance than non-native speech. However, both AE and non-native speakers showed sensitivity to lexical predictability by reducing second mentions and high frequency words. Non-native speakers with more native-like word durations, greater within-speaker word duration variance, and greater function word reduction were perceived as less accented. Overall, these findings identify word duration as an important and complex feature of foreign-accented English. PMID:21516172

  20. Analysis of the cable equation with non-local and non-singular kernel fractional derivative

    NASA Astrophysics Data System (ADS)

    Karaagac, Berat

    2018-02-01

    Recently a new concept of differentiation was introduced in the literature where the kernel was converted from non-local singular to non-local and non-singular. One of the great advantages of this new kernel is its ability to portray fading memory and also well defined memory of the system under investigation. In this paper the cable equation which is used to develop mathematical models of signal decay in submarine or underwater telegraphic cables will be analysed using the Atangana-Baleanu fractional derivative due to the ability of the new fractional derivative to describe non-local fading memory. The existence and uniqueness of the more generalized model is presented in detail via the fixed point theorem. A new numerical scheme is used to solve the new equation. In addition, stability, convergence and numerical simulations are presented.

  1. Non-convex dissipation potentials in multiscale non-equilibrium thermodynamics

    NASA Astrophysics Data System (ADS)

    Janečka, Adam; Pavelka, Michal

    2018-04-01

    Reformulating constitutive relation in terms of gradient dynamics (being derivative of a dissipation potential) brings additional information on stability, metastability and instability of the dynamics with respect to perturbations of the constitutive relation, called CR-stability. CR-instability is connected to the loss of convexity of the dissipation potential, which makes the Legendre-conjugate dissipation potential multivalued and causes dissipative phase transitions that are not induced by non-convexity of free energy, but by non-convexity of the dissipation potential. CR-stability of the constitutive relation with respect to perturbations is then manifested by constructing evolution equations for the perturbations in a thermodynamically sound way (CR-extension). As a result, interesting experimental observations of behavior of complex fluids under shear flow and supercritical boiling curve can be explained.

  2. Non-axisymmetric annular curtain stability

    NASA Astrophysics Data System (ADS)

    Ahmed, Zahir U.; Khayat, Roger E.; Maissa, Philippe; Mathis, Christian

    2013-08-01

    A stability analysis of non-axisymmetric annular curtain is carried out for an axially moving viscous jet subject in surrounding viscous gas media. The effect of inertia, surface tension, gas-to-liquid density ratio, inner-to-outer radius ratio, and gas-to-liquid viscosity ratio on the stability of the jet is studied. In general, the axisymmetric disturbance is found to be the dominant mode. However, for small wavenumber, the non-axisymmetric mode is the most unstable mode and the one likely observed in reality. Inertia and the viscosity ratio for non-axisymmetric disturbances show a similar stability influence as observed for axisymmetric disturbances. The maximum growth rate in non-axisymmetric flow, interestingly, appears at very small wavenumber for all inertia levels. The dominant wavenumber increases (decreases) with inertia for non-axisymmetric (axisymmetric) flow. Gas-to-liquid density ratio, curvature effect, and surface tension, however, exhibit an opposite influence on growth rate compared to axisymmetric disturbances. Surface tension tends to stabilize the flow with reductions of the unstable wavenumber range and the maximum growth rate as well as the dominant wavenumber. The dominant wavenumber remains independent of viscosity ratio indicating the viscosity ratio increases the breakup length of the sheet with very little influence on the size of the drops. The range of unstable wavenumbers is affected only by curvature in axisymmetric flow, whereas all the stability parameters control the range of unstable wavenumbers in non-axisymmetric flow. Inertia and gas density increase the unstable wavenumber range, whereas the radius ratio, surface tension, and the viscosity ratio decrease the unstable wavenumber range. Neutral curves are plotted to separate the stable and unstable domains. Critical radius ratio decreases linearly and nonlinearly with the wavenumber for axisymmetric and non-axisymmetric disturbances, respectively. At smaller Weber numbers, a

  3. Non-Porod scattering and non-integer scaling of resistance in rough films

    NASA Astrophysics Data System (ADS)

    Bupathy, Arunkumar; Verma, Rupesh; Banerjee, Varsha; Puri, Sanjay

    2017-04-01

    In many physical systems, films are rough due to the stochastic behavior of depositing particles. They are characterized by non-Porod power law decays in the structure factor S (k) . Theoretical studies predict anomalous diffusion in such morphologies, with important implications for diffusivity, conductivity, etc. We use the non-Porod decay to accurately determine the fractal properties of two prototypical nanoparticle films: (i) Palladium (Pd) and (ii) Cu2O. Using scaling arguments, we find that the resistance of rough films of lateral size L obeys a non-integer power law R ∼L-ζ , in contrast to integer power laws for compact structures. The exponent ζ is anisotropic. We confirm our predictions by re-analyzing experimental data from Cu2O nano-particle films. Our results are valuable for understanding recent experiments that report anisotropic electrical properties in (rough) thin films.

  4. Atopic and Non-atopic Eczema.

    PubMed

    Rożalski, Michał; Rudnicka, Lidia; Samochocki, Zbigniew

    2016-06-01

    Atopic dermatitis is a common term used in the medical literature, but according to The Nomenclature Review Committee Of The World Allergy Organization the name which should be used is eczema. Eczema is divided into two subtypes: atopic and non-atopic. These subtypes differ in the level of total immunoglobulin E (IgE) in serum, response to allergens in skin prick tests, and detection of specific IgE antibodies. Non-atopic eczema is characterized by a low level of total IgE, negative skin prick tests, and undetectable specific IgE antibodies. It is estimated that 10-45% cases of eczema are non-atopic ones. In recent studies, other features differentiating these two subtypes have been identified, such as female predominance in non-atopic eczema. A more severe course, damage of the epidermal barrier, predominance of Th2 (T helper cells 2) response, and a lower positive reaction to metal patch tests are the characteristics of the atopic subtype. In our opinion, new diagnostic criteria taking into account the non-atopic subtype of eczema need to be established.

  5. Non-HACEK gram-negative bacillus endocarditis.

    PubMed

    Morpeth, Susan; Murdoch, David; Cabell, Christopher H; Karchmer, Adolf W; Pappas, Paul; Levine, Donald; Nacinovich, Francisco; Tattevin, Pierre; Fernández-Hidalgo, Núria; Dickerman, Stuart; Bouza, Emilio; del Río, Ana; Lejko-Zupanc, Tatjana; de Oliveira Ramos, Auristela; Iarussi, Diana; Klein, John; Chirouze, Catherine; Bedimo, Roger; Corey, G Ralph; Fowler, Vance G

    2007-12-18

    Infective endocarditis caused by non-HACEK (species other than Haemophilus species, Actinobacillus actinomycetemcomitans, Cardiobacterium hominis, Eikenella corrodens, or Kingella species) gram-negative bacilli is rare, is poorly characterized, and is commonly considered to be primarily a disease of injection drug users. To describe the clinical characteristics and outcomes of patients with non-HACEK gram-negative bacillus endocarditis in a large, international, contemporary cohort of patients. Observations from the International Collaboration on Infective Endocarditis Prospective Cohort Study (ICE-PCS) database. 61 hospitals in 28 countries. Hospitalized patients with definite endocarditis. Characteristics of non-HACEK gram-negative bacillus endocarditis cases were described and compared with those due to other pathogens. Among the 2761 case-patients with definite endocarditis enrolled in ICE-PCS, 49 (1.8%) had endocarditis (20 native valve, 29 prosthetic valve or device) due to non-HACEK, gram-negative bacilli. Escherichia coli (14 patients [29%]) and Pseudomonas aeruginosa (11 patients [22%]) were the most common pathogens. Most patients (57%) with non-HACEK gram-negative bacillus endocarditis had health care-associated infection, whereas injection drug use was rare (4%). Implanted endovascular devices were frequently associated with non-HACEK gram-negative bacillus endocarditis compared with other causes of endocarditis (29% vs. 11%; P < 0.001). The in-hospital mortality rate of patients with endocarditis due to non-HACEK gram-negative bacilli was high (24%) despite high rates of cardiac surgery (51%). Because of the small number of patients with non-HACEK gram-negative bacillus endocarditis in each treatment group and the lack of long-term follow-up, strong treatment recommendations are difficult to make. In this large, prospective, multinational cohort, more than one half of all cases of non-HACEK gram-negative bacillus endocarditis were associated with

  6. A Bohmian approach to the non-Markovian non-linear Schrödinger–Langevin equation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Vargas, Andrés F.; Morales-Durán, Nicolás; Bargueño, Pedro, E-mail: p.bargueno@uniandes.edu.co

    2015-05-15

    In this work, a non-Markovian non-linear Schrödinger–Langevin equation is derived from the system-plus-bath approach. After analyzing in detail previous Markovian cases, Bohmian mechanics is shown to be a powerful tool for obtaining the desired generalized equation.

  7. Index theorem for non-supersymmetric fermions coupled to a non-Abelian string and electric charge quantization

    NASA Astrophysics Data System (ADS)

    Shifman, M.; Yung, A.

    2018-03-01

    Non-Abelian strings are considered in non-supersymmetric theories with fermions in various appropriate representations of the gauge group U(N). We derive the electric charge quantization conditions and the index theorems counting fermion zero modes in the string background both for the left-handed and right-handed fermions. In both cases we observe a non-trivial N dependence.

  8. Usefulness of non-fasting lipid parameters in children.

    PubMed

    Kubo, Toshihide; Takahashi, Kyohei; Furujo, Mahoko; Hyodo, Yuki; Tsuchiya, Hiroki; Hattori, Mariko; Fujinaga, Shoko; Urayama, Kenji

    2017-01-01

    This study assessed whether non-fasting lipid markers could be substituted for fasting markers in screening for dyslipidemia, whether direct measurement of non-fasting low-density lipoprotein cholesterol [LDL-C (D)] could be substituted for the calculation of fasting LDL-C [LDL-C (F)], and the utility of measuring non-high-density lipoprotein cholesterol (non-HDL-C). In 33 children, the lipid profile was measured in the non-fasting and fasting states within 24 h. Correlations were examined between non-fasting LDL-C (D) or non-HDL-C levels and fasting LDL-C (F) levels. Non-fasting triglyceride (TG), total cholesterol (TC), HDL-C, LDL-C (D), and non-HDL-C levels were all significantly higher than the fasting levels, but the mean difference was within 10% (except for TG). Non-fasting LDL-C (D) and non-HDL-C levels were strongly correlated with the fasting LDL-C (F) levels. In conclusion, except for TG, non-fasting lipid parameters are useful when screening children for dyslipidemia. Direct measurement of non-fasting LDL-C and calculation of non-fasting non-HDL-C could replace the calculation of fasting LDL-C because of convenience.

  9. Evaluation of non-HDL cholesterol as a predictor of non-fatal cardiovascular events in a prospective population cohort.

    PubMed

    Carbayo Herencia, Julio A; Simarro Rueda, Marta; Palazón Bru, Antonio; Molina Escribano, Francisca; Ponce García, Isabel; Artigao Ródenas, Luis Miguel; Caldevilla Bernardo, David; Divisón Garrote, Juan A; Gil Guillén, Vicente Francisco

    Non-HDL cholesterol (non-HDL-C) is becoming relevant both in its participation in cardiovascular risk assessment and as a therapeutic target. The objective of the present study was to assess the independent predictive capacity of both non-HDL-C and LDL-C (the main priority in dyslipidemias to reduce cardiovascular risk), in cardiovascular morbidity in a population-based sample. A prospective cohort study involving 1186 individuals in the non-HDL-C group and 1177 in the LDL-C group, followed for 10.7years (SD=2.2), who had not had any previous cardiovascular event. The predictor variables included in the adjustment were: gender, age, arterial hypertension, diabetes mellitus, smoker status and non-HDL-C in one group. In the other group, consisting of patients presenting TG levels of 400mg/dL, non-HDL-C was replaced by LDL-C. Survival curves (Kaplan-Meier) were calculated and two Cox regression models were applied, one for each group. Non-HDL-C group presented 6.2% of non-fatal cardiovascular episodes during follow-up and the LDL-C group 6.0%. After adjustment, for each 30mg/dL increase in non-HDL-C, the incidence of new non-fatal cardiovascular events increased by 31% (HR=1.31, 95%CI: 1.06-1.61; P=.018) and in the LDL-C group by 27% (HR=1.27, 95%CI: 0.97-1.61, P=.068). After a follow-up of 10.7years, non-HDL-C has been shown in our population as a prognostic factor of non-fatal cardiovascular disease, but not LDL-C, although its HR is close to statistical significance. Copyright © 2017 Sociedad Española de Arteriosclerosis. Publicado por Elsevier España, S.L.U. All rights reserved.

  10. Design of Phase II Non-inferiority Trials.

    PubMed

    Jung, Sin-Ho

    2017-09-01

    With the development of inexpensive treatment regimens and less invasive surgical procedures, we are confronted with non-inferiority study objectives. A non-inferiority phase III trial requires a roughly four times larger sample size than that of a similar standard superiority trial. Because of the large required sample size, we often face feasibility issues to open a non-inferiority trial. Furthermore, due to lack of phase II non-inferiority trial design methods, we do not have an opportunity to investigate the efficacy of the experimental therapy through a phase II trial. As a result, we often fail to open a non-inferiority phase III trial and a large number of non-inferiority clinical questions still remain unanswered. In this paper, we want to develop some designs for non-inferiority randomized phase II trials with feasible sample sizes. At first, we review a design method for non-inferiority phase III trials. Subsequently, we propose three different designs for non-inferiority phase II trials that can be used under different settings. Each method is demonstrated with examples. Each of the proposed design methods is shown to require a reasonable sample size for non-inferiority phase II trials. The three different non-inferiority phase II trial designs are used under different settings, but require similar sample sizes that are typical for phase II trials.

  11. 39 CFR 262.7 - Non-records.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Non-records. 262.7 Section 262.7 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RECORDS AND INFORMATION MANAGEMENT DEFINITIONS § 262.7 Non-records. (a) Non-record material. Includes blank forms and surplus publications...

  12. 39 CFR 262.7 - Non-records.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 39 Postal Service 1 2011-07-01 2011-07-01 false Non-records. 262.7 Section 262.7 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RECORDS AND INFORMATION MANAGEMENT DEFINITIONS § 262.7 Non-records. (a) Non-record material. Includes blank forms and surplus publications...

  13. 39 CFR 262.7 - Non-records.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 39 Postal Service 1 2012-07-01 2012-07-01 false Non-records. 262.7 Section 262.7 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RECORDS AND INFORMATION MANAGEMENT DEFINITIONS § 262.7 Non-records. (a) Non-record material. Includes blank forms and surplus publications...

  14. 39 CFR 262.7 - Non-records.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 39 Postal Service 1 2013-07-01 2013-07-01 false Non-records. 262.7 Section 262.7 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RECORDS AND INFORMATION MANAGEMENT DEFINITIONS § 262.7 Non-records. (a) Non-record material. Includes blank forms and surplus publications...

  15. 39 CFR 262.7 - Non-records.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 39 Postal Service 1 2014-07-01 2014-07-01 false Non-records. 262.7 Section 262.7 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RECORDS AND INFORMATION MANAGEMENT DEFINITIONS § 262.7 Non-records. (a) Non-record material. Includes blank forms and surplus publications...

  16. Non-orthodontic intervention and non-nutritive sucking behaviours: A literature review.

    PubMed

    Tanny, Liyana; Huang, Boyen; Naung, Noel Ye; Currie, Geoffrey

    2018-04-01

    Anterior open bite (AOB) is one of the most complex malocclusions to manage. AOB is caused by either by skeletal, genetic or environmental factors. Numerous treatment options are currently utilised to manage AOB. These vary from non-invasive behavioural shaping to orthodontic and surgical interventions. This paper reviews the available orthodontic and non-orthodontic interventions used in the management of AOB. The literature review was carried out using the PubMed search engine from the first of January 2000 to the first of June 2017. Two major keywords (open bite and anterior open bite) were used in addition to 23 minor keywords in the review. AOB is one of the most complex malocclusions to treat with high relapse rates. Long term outcome in treatments of patients with AOB was substantially low. Relapse rates were not taken into consideration for some of the literature reviewed. Despite limitations of the literature, it is recommended that orofacial myofunctional therapy (OMT) and non-orthodontic intervention (NOI) be used in conjunction as an effective treatment option for Anterior Open Bite. Copyright © 2018. Published by Elsevier Taiwan.

  17. Non-ionic detergents facilitate non-specific binding of M13 bacteriophage to polystyrene surfaces.

    PubMed

    Hakami, Abdulrahim R; Ball, Jonathan K; Tarr, Alexander W

    2015-09-01

    Phage-displayed random peptide libraries are widely used for identifying peptide interactions with proteins and other substrates. Selection of peptide ligands involves iterative rounds of affinity enrichment. The binding properties of the selected phage clones are routinely tested using immunoassay after propagation to high titre in a bacterial host and precipitation using polyethylene glycol (PEG) and high salt concentration. These immunoassays can suffer from low sensitivity and high background signals. Polysorbate 20 (Tween(®) 20) is a non-ionic detergent commonly used in immunoassay washing buffers to reduce non-specific binding, and is also used as a blocking reagent. We have observed that Tween 20 enhances non-specific M13 library phage binding in a peptide-independent manner. Other non-ionic detergents were also found to promote significant, dose-dependent non-specific phage binding in ELISA. This effect was not observed for assays using phage concentrated by ultracentrifugation, suggesting that interactions occur between detergents and the PEG-precipitated phage, irrespective of the displayed peptide motif. This artefact may impact on successful affinity selection of peptides from phage-display libraries. We propose alternative methods for screening phage libraries for identifying binding interactions with target ligands. Copyright © 2015 Elsevier B.V. All rights reserved.

  18. Complete mechanical behavior analysis of FG Nano Beam under non-uniform loading using non-local theory

    NASA Astrophysics Data System (ADS)

    Ghaffari, I.; Parhizkar Yaghoobi, M.; Ghannad, M.

    2018-01-01

    The purpose of this study is to offer a complete solution to analyze the mechanical behavior (bending, buckling and vibration) of Nano-beam under non-uniform loading. Furthermore, the effects of size (nonlocal parameters), non-homogeneity constants, and different boundary conditions are investigated by using this method. The exact solution presented here reduces costs incurred by experiments. In this research, the displacement field obeys the kinematics of the Euler-Bernoulli beam theory and non-local elasticity theory has been used. The governing equations and general boundary conditions are derived for a beam by using energy method. The presented solution enables us to analyze any kind of loading profile and boundary conditions with no limitations. Furthermore, this solution, unlike previous studies, is not a series-solution; hence, there is no limitation prior to existing with the series-solution, nor does it need to check convergence. Based on the developed analytical solution, the influence of size, non-homogeneity and non-uniform loads on bending, buckling and vibration behaviors is discussed. Also, the obtained result is highly accurate and in good agreement with previous research. In theoretical method, the allowable range for non-local parameters can be determined so as to make a major contribution to the reduction of the cost of experiments determining the value of non-local parameters.

  19. Non-Recurrent Laryngeal Nerve.

    PubMed

    Buła, Grzegorz; Mucha, Ryszard; Paliga, Michał; Koziołek, Henryk; Niedzielski, Zbigniew; Gawrychowski, Jacek

    2015-07-01

    The aim of the study was to assess the frequency of non-recurrent laryngeal nerves (Non-RLN). A total of 6110 patients were operated in our hospital between 1 January 2005 and 31 December 2013 for various goiters (5429) and various types of hyperparathyroidism (618). Laryngeal nerve was exposed during operation in 1700 patients from superior aperture of the chest to superior aperture of the larynx. Identification process of RLN was started with dissecting inferior thyroid artery (ITA) and its junction with the nerve. Then main trunk of the nerve was exposed backwards till the region of superior aperture of the chest together with the end portion till the nerve outlet to the larynx. In the group of 1700 patients, RLN was exposed bilaterally in 1400 (82.4%) and unilaterally in 300 (17.6%). In the group of 3100 dissected RLNs the course of RLN was observed on the right side in 1710 patients and on the left in 1390. Irreversible nature RLN was shown in four cases (0.1%) - four women (02%) aged 42-55 (mean 49.3) - three operated for non-toxic nodular goiter and one for primary hyperparathyroidism. Each time the Non-RLN was seen on the right side. The other patients manifested recurrent character RLN. Moreover, interstitial course of RLN was found on the left side in one man. Non recurrent laryngeal nerve is a rare anatomical variation, occurring more frequently on the right side. Surgeon during surgery of the thyroid and parathyroid glands should be aware of its existence to avoid damage.

  20. Non-additive non-interacting kinetic energy of rare gas dimers

    NASA Astrophysics Data System (ADS)

    Jiang, Kaili; Nafziger, Jonathan; Wasserman, Adam

    2018-03-01

    Approximations of the non-additive non-interacting kinetic energy (NAKE) as an explicit functional of the density are the basis of several electronic structure methods that provide improved computational efficiency over standard Kohn-Sham calculations. However, within most fragment-based formalisms, there is no unique exact NAKE, making it difficult to develop general, robust approximations for it. When adjustments are made to the embedding formalisms to guarantee uniqueness, approximate functionals may be more meaningfully compared to the exact unique NAKE. We use numerically accurate inversions to study the exact NAKE of several rare-gas dimers within partition density functional theory, a method that provides the uniqueness for the exact NAKE. We find that the NAKE decreases nearly exponentially with atomic separation for the rare-gas dimers. We compute the logarithmic derivative of the NAKE with respect to the bond length for our numerically accurate inversions as well as for several approximate NAKE functionals. We show that standard approximate NAKE functionals do not reproduce the correct behavior for this logarithmic derivative and propose two new NAKE functionals that do. The first of these is based on a re-parametrization of a conjoint Perdew-Burke-Ernzerhof (PBE) functional. The second is a simple, physically motivated non-decomposable NAKE functional that matches the asymptotic decay constant without fitting.

  1. Non-Alcoholic Fatty Liver Disease (NAFLD) and Non-Alcoholic Steatohepatitis (NASH) in HIV.

    PubMed

    Rockstroh, Jürgen Kurt

    2017-04-01

    Abnormal liver enzymes (LE) are common in patients infected with the human immunodeficiency virus (HIV) even in the absence of viral hepatitis or alcohol abuse. With availability of antiretroviral combination therapy, life expectancy has improved dramatically and as a consequence the spectrum of liver disease is changing. Increased reports on the development of non-alcoholic fatty liver disease (NAFLD) or non-alcoholic steatohepatitis (NASH) in HIV coinfected patients raise questions around prevalence, clinical manifestations, and clinical outcome of these liver diseases in HIV coinfection. Moreover, the potential impact of combination antiretroviral therapy as well as direct HIV effects on the emergence of non-alcoholic fatty liver disease needs to be explored. This review summarizes the recent literature on NAFLD and NASH in HIV.

  2. Non-invasive, non-radiological quantification of anteroposterior knee joint ligamentous laxity

    PubMed Central

    Russell, D. F.; Deakin, A. H.; Fogg, Q. A.; Picard, F.

    2013-01-01

    Objectives We performed in vitro validation of a non-invasive skin-mounted system that could allow quantification of anteroposterior (AP) laxity in the outpatient setting. Methods A total of 12 cadaveric lower limbs were tested with a commercial image-free navigation system using trackers secured by bone screws. We then tested a non-invasive fabric-strap system. The lower limb was secured at 10° intervals from 0° to 60° of knee flexion and 100 N of force was applied perpendicular to the tibia. Acceptable coefficient of repeatability (CR) and limits of agreement (LOA) of 3 mm were set based on diagnostic criteria for anterior cruciate ligament (ACL) insufficiency. Results Reliability and precision within the individual invasive and non-invasive systems was acceptable throughout the range of flexion tested (intra-class correlation coefficient 0.88, CR 1.6 mm). Agreement between the two systems was acceptable measuring AP laxity between full extension and 40° knee flexion (LOA 2.9 mm). Beyond 40° of flexion, agreement between the systems was unacceptable (LOA > 3 mm). Conclusions These results indicate that from full knee extension to 40° flexion, non-invasive navigation-based quantification of AP tibial translation is as accurate as the standard validated commercial system, particularly in the clinically and functionally important range of 20° to 30° knee flexion. This could be useful in diagnosis and post-operative evaluation of ACL pathology. Cite this article: Bone Joint Res 2013;2:233–7. PMID:24184443

  3. Non-polarizing beam splitter design

    NASA Astrophysics Data System (ADS)

    Qi, H. J.; Shao, J. D.; Hong, R. J.; Yi, K.; Fan, Z. X.

    2004-09-01

    In this paper a non-polarizing beam splitter design concept is presented using anisotropic thin films. Transmittance of s- and p-polarized waves can be dealt with separately. This concept can be applied to non-polarizing beam splitter designs of single wavelength and broad-band spectrum at oblique incidence. A few examples of non-polarizing beam splitters (50:50) at the design wavelength of 1064 nm and over the visible spectrum (420 nm 680 nm) are elaborated. Besides, the angular performance of these designs is examined.

  4. Securing non-volatile memory regions

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Faraboschi, Paolo; Ranganathan, Parthasarathy; Muralimanohar, Naveen

    Methods, apparatus and articles of manufacture to secure non-volatile memory regions are disclosed. An example method disclosed herein comprises associating a first key pair and a second key pair different than the first key pair with a process, using the first key pair to secure a first region of a non-volatile memory for the process, and using the second key pair to secure a second region of the non-volatile memory for the same process, the second region being different than the first region.

  5. The Forgotten Man--The Non-Faculty Non-Classified University Employee

    ERIC Educational Resources Information Center

    Hohenstein, Walter V.; Williams, Bernard Jay

    1974-01-01

    The authors describe multiple approaches to the problem of definition, stratification, and personnel policy applicable to the professional, non-faculty work force found in most American universities. (Editor)

  6. 75 FR 46838 - Special Conditions: Embraer ERJ 190-100 Series Airplane Seats With Non-Traditional, Large, Non...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-04

    ...; Special Conditions No. 25-408-SC] Special Conditions: Embraer ERJ 190-100 Series Airplane Seats With Non-Traditional, Large, Non-Metallic Panels AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final... 190- 100 series airplane. This airplane will have novel or unusual design features that include non...

  7. Non-surgical and non-chemical attempts to treat echinococcosis: do they work?

    PubMed Central

    Tamarozzi, Francesca; Vuitton, Lucine; Brunetti, Enrico; Vuitton, Dominique Angèle; Koch, Stéphane

    2014-01-01

    Cystic echinococcosis (CE) and alveolar echinococcosis (AE) are chronic, complex and neglected diseases. Their treatment depends on a number of factors related to the lesion, setting and patient. We performed a literature review of curative or palliative non-surgical, non-chemical interventions in CE and AE. In CE, some of these techniques, like radiofrequency thermal ablation (RFA), were shelved after initial attempts, while others, such as High-Intensity Focused Ultrasound, appear promising but are still in a pre-clinical phase. In AE, RFA has never been tested, however, radiotherapy or heavy-ion therapies have been attempted in experimental models. Still, application to humans is questionable. In CE, although prospective clinical studies are still lacking, therapeutic, non-surgical drainage techniques, such as PAIR (puncture, aspiration, injection, re-aspiration) and its derivatives, are now considered a useful option in selected cases. Finally, palliative, non-surgical drainage techniques such as US- or CT-guided percutaneous biliary drainage, centro-parasitic abscesses drainage, or vascular stenting were performed successfully. Recently, endoscopic retrograde cholangiopancreatography (ERCP)-associated techniques have become increasingly used to manage biliary fistulas in CE and biliary obstructions in AE. Development of pre-clinical animal models would allow testing for AE techniques developed for other indications, e.g. cancer. Prospective trials are required to determine the best use of PAIR, and associated procedures, and the indications and techniques of palliative drainage. PMID:25531730

  8. Non-associativity in non-geometric string and M-theory backgrounds, the algebra of octonions, and missing momentum modes

    DOE PAGES

    Günaydin, Murat; Lüst, Dieter; Malek, Emanuel

    2016-11-07

    We propose a non-associative phase space algebra for M-theory backgrounds with locally non-geometric fluxes based on the non-associative algebra of octonions. Our proposal is based on the observation that the non-associative algebra of the non-geometric R-flux background in string theory can be obtained by a proper contraction of the simple Malcev algebra generated by imaginary octonions. Furthermore, by studying a toy model of a four-dimensional locally non-geometric M-theory background which is dual to a twisted torus, we show that the non-geometric background is “missing” a momentum mode. The resulting seven-dimensional phase space can thus be naturally identified with the imaginarymore » octonions. This allows us to interpret the full uncontracted algebra of imaginary octonions as the uplift of the string theory R-flux algebra to M-theory, with the contraction parameter playing the role of the string coupling constant g s.« less

  9. Non-associativity in non-geometric string and M-theory backgrounds, the algebra of octonions, and missing momentum modes

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Günaydin, Murat; Lüst, Dieter; Malek, Emanuel

    We propose a non-associative phase space algebra for M-theory backgrounds with locally non-geometric fluxes based on the non-associative algebra of octonions. Our proposal is based on the observation that the non-associative algebra of the non-geometric R-flux background in string theory can be obtained by a proper contraction of the simple Malcev algebra generated by imaginary octonions. Furthermore, by studying a toy model of a four-dimensional locally non-geometric M-theory background which is dual to a twisted torus, we show that the non-geometric background is “missing” a momentum mode. The resulting seven-dimensional phase space can thus be naturally identified with the imaginarymore » octonions. This allows us to interpret the full uncontracted algebra of imaginary octonions as the uplift of the string theory R-flux algebra to M-theory, with the contraction parameter playing the role of the string coupling constant g s.« less

  10. One-eyed science: scientists, workplace reproductive hazards, and the right to work.

    PubMed

    Messing, K

    1999-01-01

    Although most occupational health research has been done with male subjects and on jobs traditionally done by men, research on reproductive hazards is an exception. Researchers were late to realize that men were exposed to reproductive hazards. However, women's health problems have been excluded from the large scientific literature on reproductive hazards, which has concentrated on hazards to fetuses. This is true even of much feminist-oriented research. This neglect is attributable to a reluctance to emphasize health hazards for women at work, since identifying those specific to women may militate against women's employment. Union action is in fact necessary to protect access to employment and health at the same time.

  11. Daring to Marry: Marriage Equality Activism After Proposition 8 as Challenge to the Assimilationist/Radical Binary in Queer Studies.

    PubMed

    Weber, Shannon

    2015-01-01

    I analyze three case studies of marriage equality activism and marriage equality-based groups after the passage of Proposition 8 in California. Evaluating the JoinTheImpact protests of 2008, the LGBTQ rights group GetEQUAL, and the group One Struggle One Fight, I argue that these groups revise queer theoretical arguments about marriage equality activism as by definition assimilationist, homonormative, and single-issue. In contrast to such claims, the cases studied here provide a snapshot of heterogeneous, intersectional, and coalition-based social justice work in which creative methods of protest, including direct action and flash mobs, are deployed in militant ways for marriage rights and beyond.

  12. Why Wars End: An Expected Utility War Termination Model

    DTIC Science & Technology

    1992-04-15

    any o( I, qelei. Thk document may not be rMeed for ope pubjckdoa untu it huA been deared by de appropriate militUay e r "e r aovsmment agency. WHY WARS...MONITORING ORGANIZATION 4I r U11f (if applicable) 6c. ADDRESS (City, State, and ZIP Code) 7b. ADDRESS (City. State, and ZIP Code) /Z OCT HfuL.I(i RL...Classification) ~ LA.’ 7Z f/ ’YA 479 , 12. PERSONAL AUTHOR(S) 𔃾 M70?’ 7- 04ŝ’- r -71 on6, .13 . TYPE OF REPORT 113b. TIME COVERED 14- DATE OF REPORT

  13. [The politics of the self: psychological science and bourgeois subjectivity in 19th century Spain.].

    PubMed

    Novella, Enric J

    2010-01-01

    This paper offers an analysis of the process of institutionalization of psychological knowledge in Spain following the educative reforms implemented during the second third of the 19th century, which prescribed its inclusion in the curricular program of the new secondary education. After a detailed examination of the theoretical orientation, the ideological assumptions and the socio-political connections of the contents transmitted to the students throughout the century, its militant spiritualism is interpreted as a highly significant attempt on the part of the liberal elites to articulate a pedagogy of subjectivity intended to counteract the trends toward reduction, naturalization and fragmentation of psychic life inherent to the development of modern science.

  14. Non-Markovian Effect in Optomechanical System

    NASA Astrophysics Data System (ADS)

    Xin, Chun Yu; Meng, Shu Sheng; Zhou, Y. H.

    2018-06-01

    Most studies on optomechanical systems have been performed under the Markovian approximation. In this paper, we extend the study from the Markovian to the non-Markovian regime. According to the Markovian optomechanically induced transparency (OMIT) theory in Weis et al. (Science 330, 1520, 2010), we propose the non-Markovian counterpart. We find that the non-Markovianity might give rise to negative absorption, i.e., the probe field gains from the environment. By calculating the mean position of the mechanical resonator (MR), we illustrate the effect of non-Markovianity on the dynamics of the moving mirror.

  15. About non standard Lagrangians in cosmology

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dimitrijevic, Dragoljub D.; Milosevic, Milan

    A review of non standard Lagrangians present in modern cosmological models will be considered. Well known example of non standard Lagrangian is Dirac-Born-Infeld (DBI) type Lagrangian for tachyon field. Another type of non standard Lagrangian under consideration contains scalar field which describes open p-adic string tachyon and is called p-adic string theory Lagrangian. We will investigate homogenous cases of both DBI and p-adic fields and obtain Lagrangians of the standard type which have the same equations of motions as aforementioned non standard one.

  16. 45 CFR 98.91 - Non-compliance.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 1 2012-10-01 2012-10-01 false Non-compliance. 98.91 Section 98.91 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION CHILD CARE AND DEVELOPMENT FUND Monitoring, Non-compliance and Complaints § 98.91 Non-compliance. (a) If after reasonable notice to a Lead Agency...

  17. Non-Periodic Helix TWT Study.

    DTIC Science & Technology

    1980-05-01

    IA-A087 413 LITTON SYSTEMS INC SAN CARLOS CA ELECTRON TUBE DIV F/6 9/1 NON-PERIODIC HELIX TWT STUDY.(U) MAY 80 N00173-76C-014 UNCLASSIFIED ML...IEEEEEEmhEEI U-80 - ’l////////,, 11111 128 25 L1. = *""L 1- 1.8 MICROCOPY RESOLUTION TEST CHART ’IT-, ( (NO-PERIODIC HELIX WTSTUDY0 I EXTENSION OF CONTRACT... Helix Circuit 4 - 2 Non-Periodic Helix Structure 7 3 Unwound Tape for Non-Periodic Helix 8 4 Typical Helix Assembly 10 5 Typical Ladder Assembly 11 6

  18. Non-Gaussianity from isocurvature perturbations

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kawasaki, Masahiro; Nakayama, Kazunori; Sekiguchi, Toyokazu

    2008-11-15

    We develop a formalism for studying non-Gaussianity in both curvature and isocurvature perturbations. It is shown that non-Gaussianity in the isocurvature perturbation between dark matter and photons leaves distinct signatures in the cosmic microwave background temperature fluctuations, which may be confirmed in future experiments, or possibly even in the currently available observational data. As an explicit example, we consider the quantum chromodynamics axion and show that it can actually induce sizable non-Gaussianity for the inflationary scale, H{sub inf} = O(10{sup 9}-10{sup 11}) GeV.

  19. 47 CFR 25.135 - Licensing provisions for earth station networks in the non-voice, non-geostationary Mobile...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Applications and Licenses Earth Stations § 25.135 Licensing provisions for earth station networks in the non... 47 Telecommunication 2 2014-10-01 2014-10-01 false Licensing provisions for earth station networks in the non-voice, non-geostationary Mobile-Satellite Service. 25.135 Section 25.135 Telecommunication...

  20. 75 FR 37 - Special Conditions: Airbus Model A330 Series Airplanes; Seats with Non-Traditional, Large, Non...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-04

    ...-traditional, large, non-metallic panels. To provide a level of safety that is equivalent to that provided by...; Special Conditions No. 25-400-SC] Special Conditions: Airbus Model A330 Series Airplanes; Seats with Non-Traditional, Large, Non-Metallic Panels AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final...

  1. Adolescents' non-core food intake: a description of what, where and with whom adolescents consume non-core foods.

    PubMed

    Toumpakari, Zoi; Haase, Anne M; Johnson, Laura

    2016-06-01

    Little is known about adolescents' non-core food intake in the UK and the eating context in which they consume non-core foods. The present study aimed to describe types of non-core foods consumed by British adolescents in total and across different eating contexts. A descriptive analysis, using cross-sectional data from food diaries. Non-core foods were classified based on cut-off points of fat and sugar from the Australian Guide to Healthy Eating. Eating context was defined as 'where' and 'with whom' adolescents consumed each food. Percentages of non-core energy were calculated for each food group in total and across eating contexts. A combined ranking was then created to account for each food's contribution to non-core energy intake and its popularity of consumption (percentage of consumers). The UK National Diet and Nutrition Survey 2008-2011. Adolescents across the UK aged 11-18 years (n 666). Non-core food comprised 39·5 % of total energy intake and was mostly 'Regular soft drinks', 'Crisps & savoury snacks', 'Chips & potato products', 'Chocolate' and 'Biscuits'. Adolescents ate 57·0 % and 51·3 % of non-core food at 'Eateries' or with 'Friends', compared with 33·2 % and 32·1 % at 'Home' or with 'Parents'. Persistent foods consumed across eating contexts were 'Regular soft drinks' and 'Chips & potato products'. Regular soft drinks contribute the most energy and are the most popular non-core food consumed by adolescents regardless of context, and represent a good target for interventions to reduce non-core food consumption.

  2. Non-Hermitian optics in atomic systems

    NASA Astrophysics Data System (ADS)

    Zhang, Zhaoyang; Ma, Danmeng; Sheng, Jiteng; Zhang, Yiqi; Zhang, Yanpeng; Xiao, Min

    2018-04-01

    A wide class of non-Hermitian Hamiltonians can possess entirely real eigenvalues when they have parity-time (PT) symmetric potentials. Recently, this family of non-Hermitian systems has attracted considerable attention in diverse areas of physics due to their extraordinary properties, especially in optical systems based on solid-state materials, such as coupled gain-loss waveguides and microcavities. Considering the desired refractive index can be effectively manipulated through atomic coherence, it is important to realize such non-Hermitian optical potentials and further investigate their distinct properties in atomic systems. In this paper, we review the recent theoretical and experimental progress of non-Hermitian optics with coherently prepared multi-level atomic configurations. The realizations of (anti-) PT symmetry with different schemes have extensively demonstrated the special optical properties of non-Hermitian optical systems with atomic coherence.

  3. Glucose tolerance test - non-pregnant

    MedlinePlus

    Oral glucose tolerance test - non-pregnant; OGTT - non-pregnant; Diabetes - glucose tolerance test; Diabetic - glucose tolerance test ... The most common glucose tolerance test is the oral glucose ... the test begins, a sample of blood will be taken. You will then ...

  4. Non-linear non-local molecular electrodynamics with nano-optical fields.

    PubMed

    Chernyak, Vladimir Y; Saurabh, Prasoon; Mukamel, Shaul

    2015-10-28

    The interaction of optical fields sculpted on the nano-scale with matter may not be described by the dipole approximation since the fields may vary appreciably across the molecular length scale. Rather than incrementally adding higher multipoles, it is advantageous and more physically transparent to describe the optical process using non-local response functions that intrinsically include all multipoles. We present a semi-classical approach for calculating non-local response functions based on the minimal coupling Hamiltonian. The first, second, and third order response functions are expressed in terms of correlation functions of the charge and the current densities. This approach is based on the gauge invariant current rather than the polarization, and on the vector potential rather than the electric and magnetic fields.

  5. 20 CFR 25.102 - How is compensation for death of a non-citizen non-resident employee paid?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 1 2013-04-01 2012-04-01 true How is compensation for death of a non-citizen... PROGRAMS, DEPARTMENT OF LABOR FEDERAL EMPLOYEES' COMPENSATION ACT COMPENSATION FOR DISABILITY AND DEATH OF... compensation for death of a non-citizen non-resident employee paid? If the disability causes death, the...

  6. 20 CFR 25.102 - How is compensation for death of a non-citizen non-resident employee paid?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 1 2014-04-01 2012-04-01 true How is compensation for death of a non-citizen... PROGRAMS, DEPARTMENT OF LABOR FEDERAL EMPLOYEES' COMPENSATION ACT COMPENSATION FOR DISABILITY AND DEATH OF... compensation for death of a non-citizen non-resident employee paid? If the disability causes death, the...

  7. Non-technical skills assessment in surgery.

    PubMed

    Sharma, Bharat; Mishra, Amit; Aggarwal, Rajesh; Grantcharov, Teodor P

    2011-09-01

    Adverse events in surgery have highlighted the importance of non-technical skills, such as communication, decision-making, teamwork, situational awareness and leadership, to effective organizational performance. These skills carry particular importance to surgical oncology, as members of a multidisciplinary team must work cohesively to formulate effective patient care plans. Several non-technical skills evaluation tools have been developed for use in surgery, without adequate comparison and consensus on which should be standard for training. Eleven articles describing the use of three non-technical evaluation tools related to surgery: NOTSS (Non Technical Skills for Surgeons), NOTECHS (Non Technical Skills) and OTAS (Observational Teamwork Assessment for Surgery) were analyzed with respect to scale formulation, validity, reliability and feasibility. Furthermore, their use in training thus far and the future of non-technical rating scales in surgical curricula was discussed. Future work should focus on incorporating these assessment tools into training and into a real operating room setting to provide formative evaluations for surgical residents. Copyright © 2010 Elsevier Ltd. All rights reserved.

  8. Non-affine deformations in polymer hydrogels

    PubMed Central

    Wen, Qi; Basu, Anindita; Janmey, Paul A.; Yodh, A. G.

    2012-01-01

    Most theories of soft matter elasticity assume that the local strain in a sample after deformation is identical everywhere and equal to the macroscopic strain, or equivalently that the deformation is affine. We discuss the elasticity of hydrogels of crosslinked polymers with special attention to affine and non-affine theories of elasticity. Experimental procedures to measure non-affine deformations are also described. Entropic theories, which account for gel elasticity based on stretching out individual polymer chains, predict affine deformations. In contrast, simulations of network deformation that result in bending of the stiff constituent filaments generally predict non-affine behavior. Results from experiments show significant non-affine deformation in hydrogels even when they are formed by flexible polymers for which bending would appear to be negligible compared to stretching. However, this finding is not necessarily an experimental proof of the non-affine model for elasticity. We emphasize the insights gained from experiments using confocal rheoscope and show that, in addition to filament bending, sample micro-inhomogeneity can be a significant alternative source of non-affine deformation. PMID:23002395

  9. Reducing non-attendance at outpatient clinics.

    PubMed

    Stone, C A; Palmer, J H; Saxby, P J; Devaraj, V S

    1999-03-01

    Outpatient non-attendance is a common source of inefficiency in a health service, wasting time and resources and potentially lengthening waiting lists. A prospective audit of plastic surgery outpatient clinics was conducted during the six months from January to June 1997, to determine the clinical and demographic profile of non-attenders. Of 6095 appointments 16% were not kept. Using the demographic information, we changed our follow-up guidelines to reflect risk factors for multiple non-attendances, and a self-referral clinic was introduced to replace routine follow-up for high risk non-attenders. After these changes, a second audit in the same six months of 1998 revealed a non-attendance rate of 11%--i.e. 30% lower than before. Many follow-up appointments are sent inappropriately to patients who do not want further attention. This study, indicating how risk factor analysis can identify a group of patients who are unlikely to attend again after one missed appointment, may be a useful model for the reduction of outpatient non-attendance in other specialties.

  10. Oligonucleotide-based pharmaceuticals: Non-clinical and clinical safety signals and non-clinical testing strategies.

    PubMed

    Mustonen, Enni-Kaisa; Palomäki, Tiina; Pasanen, Markku

    2017-11-01

    Antisense oligonucleotides, short interfering RNAs (siRNAs) and aptamers are oligonucleotide-based pharmaceuticals with a promising role in targeted therapies. Currently, five oligonucleotide-based pharmaceuticals have achieved marketing authorization in Europe or USA and many more are undergoing clinical testing. However, several safety concerns have been raised in non-clinical and clinical studies. Oligonucleotides share properties with both chemical and biological pharmaceuticals and therefore they pose challenges also from the regulatory point of view. We have analyzed the safety data of oligonucleotides and evaluated the applicability of current non-clinical toxicological guidelines for assessing the safety of oligonucleotide-based pharmaceuticals. Oligonucleotide-based pharmaceuticals display a similar toxicological profile, exerting adverse effects on liver and kidney, evoking hematological alterations, as well as causing immunostimulation and prolonging the coagulation time. It is possible to extrapolate some of these effects from non-clinical studies to humans. However, evaluation strategies for genotoxicity testing of "non-natural" oligonucleotides should be revised. Additionally, the selective use of surrogates and prediction of clinical endpoints for non-clinically observed immunostimulation is complicated by its multiple potential manifestations, demanding improvements in the testing strategies. Utilizing more relevant and mechanistic-based approaches and taking better account of species differences, could possibly improve the prediction of relevant immunological/proinflammatory effects in humans. Copyright © 2017 Elsevier Inc. All rights reserved.

  11. 20 CFR 25.102 - How is compensation for death of a non-citizen non-resident employee paid?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 1 2012-04-01 2012-04-01 false How is compensation for death of a non... DEATH OF NONCITIZEN FEDERAL EMPLOYEES OUTSIDE THE UNITED STATES The Special Schedule of Compensation § 25.102 How is compensation for death of a non-citizen non-resident employee paid? If the disability...

  12. Non-linear quantum-classical scheme to simulate non-equilibrium strongly correlated fermionic many-body dynamics

    PubMed Central

    Kreula, J. M.; Clark, S. R.; Jaksch, D.

    2016-01-01

    We propose a non-linear, hybrid quantum-classical scheme for simulating non-equilibrium dynamics of strongly correlated fermions described by the Hubbard model in a Bethe lattice in the thermodynamic limit. Our scheme implements non-equilibrium dynamical mean field theory (DMFT) and uses a digital quantum simulator to solve a quantum impurity problem whose parameters are iterated to self-consistency via a classically computed feedback loop where quantum gate errors can be partly accounted for. We analyse the performance of the scheme in an example case. PMID:27609673

  13. Non-invasive diagnostic platforms in management of non-small cell lung cancer: opportunities and challenges

    PubMed Central

    Pennell, Nathan A.

    2017-01-01

    Several non-invasive diagnostic platforms are already being incorporated in routine clinical practice in the work up and monitoring of patients with lung cancer. These approaches have great potential to improve patient selection and monitor patients while on therapy, however several challenges exist in clinical validation and standardization of such platforms. In this review, we summarize the current technologies available for non-invasive diagnostic evaluation from the blood of patients with non-small cell lung cancer (NSCLC), and discuss the technical and logistical challenges associated incorporating such testing in clinical practice. PMID:29057238

  14. Frontal Non-Invasive Neurostimulation Modulates Antisaccade Preparation in Non-Human Primates

    PubMed Central

    Valero-Cabre, Antoni; Wattiez, Nicolas; Monfort, Morgane; François, Chantal; Rivaud-Péchoux, Sophie; Gaymard, Bertrand; Pouget, Pierre

    2012-01-01

    A combination of oculometric measurements, invasive electrophysiological recordings and microstimulation have proven instrumental to study the role of the Frontal Eye Field (FEF) in saccadic activity. We hereby gauged the ability of a non-invasive neurostimulation technology, Transcranial Magnetic Stimulation (TMS), to causally interfere with frontal activity in two macaque rhesus monkeys trained to perform a saccadic antisaccade task. We show that online single pulse TMS significantly modulated antisaccade latencies. Such effects proved dependent on TMS site (effects on FEF but not on an actively stimulated control site), TMS modality (present under active but not sham TMS on the FEF area), TMS intensity (intensities of at least 40% of the TMS machine maximal output required), TMS timing (more robust for pulses delivered at 150 ms than at 100 post target onset) and visual hemifield (relative latency decreases mainly for ipsilateral AS). Our results demonstrate the feasibility of using TMS to causally modulate antisaccade-associated computations in the non-human primate brain and support the use of this approach in monkeys to study brain function and its non-invasive neuromodulation for exploratory and therapeutic purposes. PMID:22701691

  15. Modeling non-stationary, non-axisymmetric heat patterns in DIII-D tokamak

    DOE PAGES

    Ciro, D.; Evans, T. E.; Caldas, I. L.

    2016-10-27

    Non-axisymmetric stationary magnetic perturbations lead to the formation of homoclinic tangles near the divertor magnetic saddle in tokamak discharges. These tangles intersect the divertor plates in static helical structures that delimit the regions reached by open magnetic field lines reaching the plasma column and leading the charged particles to the strike surfaces by parallel transport. In this article we introduce a non-axisymmetric rotating magnetic perturbation to model the time evolution of the three-dimensional magnetic field of a singlenull DIII-D tokamak discharge developing a rotating tearing mode. The non-axiymmetric field is modeled using the magnetic signals to adjust the phases andmore » currents of a set of internal filamentary currents that approximate the magnetic field in the plasma edge region. The stable and unstable manifolds of the asymmetric magnetic saddle are obtained through an adaptive calculation providing the cuts at a given poloidal plane and the strike surfaces. Lastly, for the modeled shot, the experimental heat pattern and its time development are well described by the rotating unstable manifold, indicating the emergence of homoclinic lobes in a rotating frame due to the plasma instabilities.« less

  16. Modeling non-stationary, non-axisymmetric heat patterns in DIII-D tokamak

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ciro, D.; Evans, T. E.; Caldas, I. L.

    Non-axisymmetric stationary magnetic perturbations lead to the formation of homoclinic tangles near the divertor magnetic saddle in tokamak discharges. These tangles intersect the divertor plates in static helical structures that delimit the regions reached by open magnetic field lines reaching the plasma column and leading the charged particles to the strike surfaces by parallel transport. In this article we introduce a non-axisymmetric rotating magnetic perturbation to model the time evolution of the three-dimensional magnetic field of a singlenull DIII-D tokamak discharge developing a rotating tearing mode. The non-axiymmetric field is modeled using the magnetic signals to adjust the phases andmore » currents of a set of internal filamentary currents that approximate the magnetic field in the plasma edge region. The stable and unstable manifolds of the asymmetric magnetic saddle are obtained through an adaptive calculation providing the cuts at a given poloidal plane and the strike surfaces. Lastly, for the modeled shot, the experimental heat pattern and its time development are well described by the rotating unstable manifold, indicating the emergence of homoclinic lobes in a rotating frame due to the plasma instabilities.« less

  17. The Origins of Scintillator Non-Proportionality

    NASA Astrophysics Data System (ADS)

    Moses, W. W.; Bizarri, G. A.; Williams, R. T.; Payne, S. A.; Vasil'ev, A. N.; Singh, J.; Li, Q.; Grim, J. Q.; Choong, W.-S.

    2012-10-01

    Recent years have seen significant advances in both theoretically understanding and mathematically modeling the underlying causes of scintillator non-proportionality. The core cause is that the interaction of radiation with matter invariably leads to a non-uniform ionization density in the scintillator, coupled with the fact that the light yield depends on the ionization density. The mechanisms that lead to the luminescence dependence on ionization density are incompletely understood, but several important features have been identified, notably Auger-like processes (where two carriers of excitation interact with each other, causing one to de-excite non-radiatively), the inability of excitation carriers to recombine (caused either by trapping or physical separation), and the carrier mobility. This paper reviews the present understanding of the fundamental origins of scintillator non-proportionality, specifically the various theories that have been used to explain non-proportionality.

  18. Membrane separation for non-aqueous solution

    NASA Astrophysics Data System (ADS)

    Widodo, S.; Khoiruddin; Ariono, D.; Subagjo; Wenten, I. G.

    2018-01-01

    Membrane technology has been widely used in a number of applications competing with conventional technologies in various ways. Despite the enormous applications, they are mainly used for the aqueous system. The use of membrane-based processes in a non-aqueous system is an emerging area. This is because developed membranes are still limited in separations involving aqueous solution which show several drawbacks when implemented in a non-aqueous system. The purpose of this paper is to provide a review of the current application of membrane processes in non-aqueous solutions, such as mineral oil treatment, vegetable oil processing, and organic solvent recovery. Developments of advanced membrane materials for the non-aqueous solutions such as super-hydrophobic and organic solvent resistant membranes are reviewed. In addition, challenges and future outlook of membrane separation for the non-aqueous solution are discussed.

  19. Schmallenberg virus non-structural protein NSm: Intracellular distribution and role of non-hydrophobic domains.

    PubMed

    Kraatz, Franziska; Wernike, Kerstin; Reiche, Sven; Aebischer, Andrea; Reimann, Ilona; Beer, Martin

    2018-03-01

    Schmallenberg virus (SBV) induces fetal malformation, abortions and stillbirth in ruminants. While the non-structural protein NSs is a major virulence factor, the biological function of NSm, the second non-structural protein which consists of three hydrophobic transmembrane (I, III, V) and two non-hydrophobic regions (II, IV), is still unknown. Here, a series of NSm mutants displaying deletions of nearly the entire NSm or of the non-hydrophobic domains was generated and the intracellular distribution of NSm was assessed. SBV-NSm is dispensable for the generation of infectious virus and mutants lacking domains II - V showed growth properties similar to the wild-type virus. In addition, a comparable intracellular distribution of SBV-NSm was observed in mammalian cells infected with domain II mutants or wild-type virus. In both cases, NSm co-localized with the glycoprotein Gc in the Golgi compartment. However, domain IV-deletion mutants showed an altered distribution pattern and no co-localization of NSm and Gc. Copyright © 2018 Elsevier Inc. All rights reserved.

  20. Non-equilibrium transport in the quantum dot: quench dynamics and non-equilibrium steady state

    NASA Astrophysics Data System (ADS)

    Culver, Adrian; Andrei, Natan

    We calculate the non-equilibrium current driven by a voltage drop across a quantum dot. The system is described by the two lead Anderson model at zero temperature with on-site Coulomb repulsion and non-interacting, linearized leads. We prepare the system in an initial state consisting of a free Fermi sea in each lead with the voltage drop given as the difference between the two Fermi levels. We quench the system by coupling the dot to the leads at t =0 and following the time evolution of the wavefunction. In the long time limit a new type of Bethe Ansatz wavefunction emerges, which satisfies the Lippmann-Schwinger equation with the two Fermi seas serving as the boundary conditions. The solution describes the non-equilibrium steady state of the system. We use this solution to compute the infinite time limit of the expectation value of the current operator at a given voltage, yielding the I-V characteristic. The calculation is non-perturbative and exact. Research supported by NSF Grant DMR 1410583.

  1. Non-equilibrium transport in the quantum dot: quench dynamics and non-equilibrium steady state

    NASA Astrophysics Data System (ADS)

    Culver, Adrian; Andrei, Natan

    We present an exact method of calculating the non-equilibrium current driven by a voltage drop across a quantum dot. The system is described by the two lead Anderson model at zero temperature with on-site Coulomb repulsion and non-interacting, linearized leads. We prepare the system in an initial state consisting of a free Fermi sea in each lead with the voltage drop given as the difference between the two Fermi levels. We quench the system by coupling the dot to the leads at t = 0 and following the time evolution of the wavefunction. In the long time limit a new type of Bethe Ansatz wavefunction emerges, which satisfies the Lippmann-Schwinger equation with the two Fermi seas serving as the boundary conditions. This exact, non-perturbative solution describes the non-equilibrium steady state of the system. We describe how to use this solution to compute the infinite time limit of the expectation value of the current operator at a given voltage, which would yield the I-V characteristic of the dot. Research supported by NSF Grant DMR 1410583.

  2. Treating non-tubal ectopic pregnancy.

    PubMed

    Chetty, Maya; Elson, Janine

    2009-08-01

    The purpose of this review is to examine the current state of knowledge regarding the treatment of non-tubal ectopic pregnancies. This review looks at the management of cervical, caesarean scar, ovarian, interstitial, cornual and abdominal pregnancies. Traditionally these pregnancies have been diagnosed late and managed by open surgery. Earlier diagnosis has led to the use of minimal access techniques, medical and conservative management for all types of non-tubal pregnancies. Increased awareness and the experience of specialised centres have led to an improved understanding of the best way to manage non-tubal ectopic pregnancies and the development of new techniques.

  3. Non-linear osmosis

    PubMed Central

    Diamond, Jared M.

    1966-01-01

    1. The relation between osmotic gradient and rate of osmotic water flow has been measured in rabbit gall-bladder by a gravimetric procedure and by a rapid method based on streaming potentials. Streaming potentials were directly proportional to gravimetrically measured water fluxes. 2. As in many other tissues, water flow was found to vary with gradient in a markedly non-linear fashion. There was no consistent relation between the water permeability and either the direction or the rate of water flow. 3. Water flow in response to a given gradient decreased at higher osmolarities. The resistance to water flow increased linearly with osmolarity over the range 186-825 m-osM. 4. The resistance to water flow was the same when the gall-bladder separated any two bathing solutions with the same average osmolarity, regardless of the magnitude of the gradient. In other words, the rate of water flow is given by the expression (Om — Os)/[Ro′ + ½k′ (Om + Os)], where Ro′ and k′ are constants and Om and Os are the bathing solution osmolarities. 5. Of the theories advanced to explain non-linear osmosis in other tissues, flow-induced membrane deformations, unstirred layers, asymmetrical series-membrane effects, and non-osmotic effects of solutes could not explain the results. However, experimental measurements of water permeability as a function of osmolarity permitted quantitative reconstruction of the observed water flow—osmotic gradient curves. Hence non-linear osmosis in rabbit gall-bladder is due to a decrease in water permeability with increasing osmolarity. 6. The results suggest that aqueous channels in the cell membrane behave as osmometers, shrinking in concentrated solutions of impermeant molecules and thereby increasing membrane resistance to water flow. A mathematical formulation of such a membrane structure is offered. PMID:5945254

  4. Non-Traditional Transfer Student Attrition

    ERIC Educational Resources Information Center

    Monroe, Anne

    2006-01-01

    Current literature focuses on traditional student attrition and on transfer transition, but little information is available on the non-traditional transfer student experience. The following study explores the process of non-traditional transfer student attrition through an investigation that illustrates the importance of past student experiences,…

  5. Current Research on Non-Coding Ribonucleic Acid (RNA).

    PubMed

    Wang, Jing; Samuels, David C; Zhao, Shilin; Xiang, Yu; Zhao, Ying-Yong; Guo, Yan

    2017-12-05

    Non-coding ribonucleic acid (RNA) has without a doubt captured the interest of biomedical researchers. The ability to screen the entire human genome with high-throughput sequencing technology has greatly enhanced the identification, annotation and prediction of the functionality of non-coding RNAs. In this review, we discuss the current landscape of non-coding RNA research and quantitative analysis. Non-coding RNA will be categorized into two major groups by size: long non-coding RNAs and small RNAs. In long non-coding RNA, we discuss regular long non-coding RNA, pseudogenes and circular RNA. In small RNA, we discuss miRNA, transfer RNA, piwi-interacting RNA, small nucleolar RNA, small nuclear RNA, Y RNA, single recognition particle RNA, and 7SK RNA. We elaborate on the origin, detection method, and potential association with disease, putative functional mechanisms, and public resources for these non-coding RNAs. We aim to provide readers with a complete overview of non-coding RNAs and incite additional interest in non-coding RNA research.

  6. The impact of non-alcoholic fatty liver disease on incident type 2 diabetes mellitus in non-overweight individuals.

    PubMed

    Fukuda, Takuya; Hamaguchi, Masahide; Kojima, Takao; Hashimoto, Yoshitaka; Ohbora, Akihiro; Kato, Takahiro; Nakamura, Naoto; Fukui, Michiaki

    2016-02-01

    The aim of this study was to evaluate the impact of non-alcoholic fatty liver disease (NAFLD) on incident type 2 diabetes mellitus (T2DM) in non-overweight individuals with NAFLD. A population-based retrospective cohort study of 4629 participants who were enrolled in a health check-up programme for more than 10 years. A standardized questionnaire and abdominal ultrasonography were used to diagnose NAFLD. A cut-off point of BMI 23 kg/m(2) was used to define overweight (≥23.0 kg/m(2)) or non-overweight (<23.0 kg/m(2)). The primary outcome was incident T2DM. Over a mean follow-up of 12.8 years, 351 participants (7.6%) developed T2DM. The incidence rate of T2DM was 3.2% in the non-overweight without NAFLD group, 14.4% in the non-overweight with NAFLD group, 8.0% in the overweight without NAFLD group and 26.4% in the overweight with NAFLD group. The adjusted hazard ratios for incident T2DM compared with the non-overweight without NAFLD group were as follows: 3.59 (95% CI: 2.14-5.76) in the non-overweight with NAFLD group, 1.99 (95% CI: 1.47-2.69) in the overweight without NAFLD group and 6.77 (95% CI: 5.17-8.91) in the overweight with NAFLD group. The adjusted hazard ratio in the non-overweight with NAFLD group was significantly higher than that in the overweight without NAFLD group or that in the non-overweight without NAFLD group. Non-overweight individuals with NAFLD had a high risk of incident T2DM. Diagnosis of NAFLD is important in non-overweight individuals, and therefore it might be necessary to follow their health conditions on a long-term basis after detection of NAFLD. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  7. Non-equilibrium Green's functions method: Non-trivial and disordered leads

    NASA Astrophysics Data System (ADS)

    He, Yu; Wang, Yu; Klimeck, Gerhard; Kubis, Tillmann

    2014-11-01

    The non-equilibrium Green's function algorithm requires contact self-energies to model charge injection and extraction. All existing approaches assume infinitely periodic leads attached to a possibly quite complex device. This contradicts today's realistic devices in which contacts are spatially inhomogeneous, chemically disordered, and impacting the overall device characteristics. This work extends the complex absorbing potentials method for arbitrary, ideal, or non-ideal leads in atomistic tight binding representation. The algorithm is demonstrated on a Si nanowire with periodic leads, a graphene nanoribbon with trumpet shape leads, and devices with leads of randomly alloyed Si0.5Ge0.5. It is found that alloy randomness in the leads can reduce the predicted ON-state current of Si0.5Ge0.5 transistors by 45% compared to conventional lead methods.

  8. Non-Commutative Martingale Inequalities

    NASA Astrophysics Data System (ADS)

    Pisier, Gilles; Xu, Quanhua

    We prove the analogue of the classical Burkholder-Gundy inequalites for non-commutative martingales. As applications we give a characterization for an Ito-Clifford integral to be an Lp-martingale via its integrand, and then extend the Ito-Clifford integral theory in L2, developed by Barnett, Streater and Wilde, to Lp for all 1non-commutative analogue of the classical Fefferman duality between $H1 and BMO.

  9. A biorthogonal decomposition for the identification and simulation of non-stationary and non-Gaussian random fields

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zentner, I.; Ferré, G., E-mail: gregoire.ferre@ponts.org; Poirion, F.

    2016-06-01

    In this paper, a new method for the identification and simulation of non-Gaussian and non-stationary stochastic fields given a database is proposed. It is based on two successive biorthogonal decompositions aiming at representing spatio–temporal stochastic fields. The proposed double expansion allows to build the model even in the case of large-size problems by separating the time, space and random parts of the field. A Gaussian kernel estimator is used to simulate the high dimensional set of random variables appearing in the decomposition. The capability of the method to reproduce the non-stationary and non-Gaussian features of random phenomena is illustrated bymore » applications to earthquakes (seismic ground motion) and sea states (wave heights).« less

  10. Non-Coalescence Effects in Microgravity

    NASA Technical Reports Server (NTRS)

    Neitzel, G. Paul

    1998-01-01

    Non-coalescence of two bodies of the same liquid and the suppression of contact between liquid drops and solid surfaces is being studied through a pair of parallel investigations being conducted at the Georgia Institute of Technology and the Microgravity Research and Support (MARS) Center in Naples, Italy. Both non-coalescence and contact suppression are achieved by exploiting the mechanism of thermocapillary convection to drive a lubricating film of surrounding gas (air) into the space between the two liquid free surfaces (non-coalescence) or between the drop free surface and the solid (contact suppression). Earlier experiments performed included flow-visualization experiments in both axisymmetric and (nearly) two-dimensional geometries and quantitative measurements of film thickness in the contact-suppression case in both geometries. Work done in the second year has focused on obtaining quantitative results relating to the effects of variable air pressure, development of analytical and numerical models of non-coalescing droplets and to pursuing potential applications of these self-lubricated systems.

  11. Non-completion and informed consent.

    PubMed

    Wertheimer, Alan

    2014-02-01

    There is a good deal of biomedical research that does not produce scientifically useful data because it fails to recruit a sufficient number of subjects. This fact is typically not disclosed to prospective subjects. In general, the guidance about consent concerns the information required to make intelligent self-interested decisions and ignores some of the information required for intelligent altruistic decisions. Bioethics has worried about the 'therapeutic misconception', but has ignored the 'completion misconception'. This article argues that, other things being equal, prospective subjects should be informed about the possibility of non-completion as part of the standard consent process if (1) it is or should be anticipatable that there is a non-trivial possibility of non-completion and (2) that information is likely to be relevant to a prospective subject's decision to consent. The article then considers several objections to the argument, including the objection that disclosing non-completion information would make recruitment even more difficult.

  12. Non-Systemic Drugs: A Critical Review

    PubMed Central

    Charmot, Dominique

    2012-01-01

    Non-systemic drugs act within the intestinal lumen without reaching the systemic circulation. The first generation included polymeric resins that sequester phosphate ions, potassium ions, or bile acids for the treatment of electrolyte imbalances or hypercholesteremia. The field has evolved towards non-absorbable small molecules or peptides targeting luminal enzymes or transporters for the treatment of mineral metabolism disorders, diabetes, gastrointestinal (GI) disorders, and enteric infections. From a drug design and development perspective, non-systemic agents offer novel opportunities to address unmet medical needs while minimizing toxicity risks, but also present new challenges, including developing a better understanding and control of non-transcellular leakage pathways into the systemic circulation. The pharmacokinetic-pharmacodynamic relationship of drugs acting in the GI tract can be complex due to the variability of intestinal transit, interaction with chyme, and the complex environment of the surface epithelia. We review the main classes of non-absorbable agents at various stages of development, and their therapeutic potential and limitations. The rapid progress in the identification of intestinal receptors and transporters, their functional characterization and role in metabolic and inflammatory disorders, will undoubtedly renew interest in the development of novel, safe, non-systemic therapeutics. PMID:22300258

  13. Traumatic and non-traumatic adrenal emergencies.

    PubMed

    Chernyak, Victoria; Patlas, Michael N; Menias, Christine O; Soto, Jorge A; Kielar, Ania Z; Rozenblit, Alla M; Romano, Luigia; Katz, Douglas S

    2015-12-01

    Multiple traumatic and non-traumatic adrenal emergencies are occasionally encountered during the cross-sectional imaging of emergency department patients. Traumatic adrenal hematomas are markers of severe polytrauma, and can be easily overlooked due to multiple concomitant injuries. Patients with non-traumatic adrenal emergencies usually present to an emergency department with a non-specific clinical picture. The detection and management of adrenal emergencies is based on cross-sectional imaging. Adrenal hemorrhage, adrenal infection, or rupture of adrenal neoplasm require immediate detection to avoid dire consequences. More often however, adrenal emergencies are detected incidentally in patients being investigated for non-specific acute abdominal pain. A high index of suspicion is required for the establishment of timely diagnosis and to avert potentially life-threatening complications. We describe cross-sectional imaging findings in patients with traumatic and non-traumatic adrenal hemorrhage, adrenal infarctions, adrenal infections, and complications of adrenal masses.

  14. Trends of non-union and prescriptions for non-steroidal anti-inflammatory drugs in the United States, 1993-2012.

    PubMed

    Wang, Zhong; Bhattacharyya, Timothy

    2015-01-01

    Surgical care and pain management for patients with fractures have evolved over the years. We wanted to ascertain if there were any changes in the incidence of non-unions and, if so, whether the use of non-steroidal anti-inflammatory drugs (NSAIDs), including COX-2 selective inhibitors, might have an effect. We used the National Inpatient Sample (NIS) to estimate the annual number of patients hospitalized for surgical treatment of a non-union between 1993 and 2012, and calculated age-adjusted rates of non-union. We estimated the prevalence of prescriptions for NSAIDs from 1996 through 2012 using the Medical Expenditure Panel Survey (MEPS). The interrupted time-series analysis was used to relate quarterly rates of non-union to changes in prescriptions for NSAIDs between 1996 and 2009. The annual estimate of non-unions in the USA declined 30% from 25,634 in 1993 to 17,815 in 2012 (p < 0.001). Specifically, the age-adjusted rate of non-unions decreased by 44% from 8.6 per 10(5) persons in 1996 to 4.8 per 10(5) persons in 2012 (p < 0.001). However, there was an 8% increase in the incidence rate of non-unions (p = 0.003) between 2000 and 2004, when certain COX-2 selective inhibitors were on the market and their prescriptions were prevalent at around 6% among those with fractures. A drop in non-union estimates from 22,321 in 2010 to 18,789 in 2011 (p = 0.04) also coincided with a marked decrease in prescriptions for NSAIDs in patients with fractures, from 22% to 14% (p = 0.02). Non-unions in the USA declined substantially between 1993 and 2012, but this was interrupted by changes in prescriptions for NSAIDs, with sustained increases between 2000 and 2004 followed by transient decreases in 2005 and 2011.

  15. Guidance for Using Non-Definitive Endpoints in Evaluating Risks to Listed and Non-listed Animal Species

    EPA Pesticide Factsheets

    Ensure consistency among OPP scientists in the use of non-definitive toxicity endpoints for terrestrial and aquatic animals when conducting ecological risk assessments for pesticides and federally listed and non-listed species.

  16. A Non-Incompressible Non-Boussinesq (NINB) framework for studying atmospheric turbulence

    NASA Astrophysics Data System (ADS)

    Yan, C.; Archer, C. L.; Xie, S.; Ghaisas, N.

    2015-12-01

    The incompressible assumption is widely used for studying the turbulent atmospheric boundary layer (ABL) and is generally accepted when the Mach number < ~0.3 (velocity < ~100 m/s). Since the tips of modern wind turbine blades can reach and exceed this threshold, neglecting air compressibility will introduce errors. In addition, if air incompressibility does not hold, then the Boussinesq approximation, by which air density is treated as a constant except in the gravity term of the Navier-Stokes equation, is also invalidated. Here, we propose a new theoretical framework, called NINB for Non-Incompressible Non-Boussinesq, in which air is not considered incompressible and air density is treated as a non-turbulent 4D variable. First, the NINB mass, momentum, and energy conservation equations are developed using Reynolds averaging. Second, numerical simulations of the NINB equations, coupled with a k-epsilon turbulence model, are performed with the finite-volume method. Wind turbines are modeled with the actuator-line model using SOWFA (Software for Offshore/onshore Wind Farm Applications). Third, NINB results are compared with the traditional incompressible buoyant simulations performed by SOWFA with the same set up. The results show differences between NINB and traditional simulations in the neutral atmosphere with a wind turbine. The largest differences in wind speed (up to 1 m/s), turbulent kinetic energy (~10%), dissipation rate (~5%), and shear stress (~10%) occur near the turbine tip region. The power generation differences are 5-15% (depending on setup). These preliminary results suggest that compressibility effects are non-negligible around wind turbines and should be taken into account when forecasting wind power. Since only a few extra terms are introduced, the NINB framework may be an alternative to the traditional incompressible Boussinesq framework for studying the turbulent ABL in general (i.e., without turbines) in the absence of shock waves.

  17. Challenges and Prospect of Non-aqueous Non-alkali (NANA) Metal-Air Batteries.

    PubMed

    Gelman, Danny; Shvartsev, Boris; Ein-Eli, Yair

    2016-12-01

    Non-aqueous non-alkali (NANA) metal-air battery technologies promise to provide electrochemical energy storage with the highest specific energy density. Metal-air battery technology is particularly advantageous being implemented in long-range electric vehicles. Up to now, almost all the efforts in the field are focused on Li-air cells, but other NANA metal-air battery technologies emerge. The major concern, which the research community should be dealing with, is the limited and rather poor rechargeability of these systems. The challenges we are covering in this review are related to the initial limited discharge capacities and cell performances. By comprehensively reviewing the studies conducted so far, we show that the implementation of advanced materials is a promising approach to increase metal-air performance and, particularly, metal surface activation as a prime achievement leading to respectful discharge currents. In this review, we address the most critical areas that need careful research attention in order to achieve progress in the understanding of the physical and electrochemical processes in non-aqueous electrolytes applied in beyond lithium and zinc air generation of metal-air battery systems.

  18. Neuro-ophthalmological presentation of non-invasive Aspergillus sinus disease in the non-immunocompromised host.

    PubMed Central

    Brown, P; Demaerel, P; McNaught, A; Revesz, T; Graham, E; Kendall, B E; Plant, G

    1994-01-01

    Two cases of non-invasive aspergillosis of the nose and paranasal sinuses are described. The first presented with left proptosis and ophthalmoplegia. Imaging and histology showed a maxillary sinus aspergilloma. The second case presented as a compressive optic neuropathy and histology showed allergic aspergillus sinusitis. The pathological distinction between invasive and non-invasive forms of aspergillus sinusitis is important as in invasive aspergillosis surgical treatment is most effectively combined with systemic antifungal treatment, whereas in aspergilloma of the paranasal sinuses surgical drainage of the sinuses alone is usually sufficient, and in allergic aspergillus sinusitis surgery is best combined with systemic or topical steroids. The distinction between invasive and non-invasive forms is particularly important as both may present with cranial neuropathies. Images PMID:8126516

  19. Negative optical spin torque wrench of a non-diffracting non-paraxial fractional Bessel vortex beam

    NASA Astrophysics Data System (ADS)

    Mitri, F. G.

    2016-10-01

    An absorptive Rayleigh dielectric sphere in a non-diffracting non-paraxial fractional Bessel vortex beam experiences a spin torque. The axial and transverse radiation spin torque components are evaluated in the dipole approximation using the radiative correction of the electric field. Particular emphasis is given on the polarization as well as changing the topological charge α and the half-cone angle of the beam. When α is zero, the axial spin torque component vanishes. However, when α becomes a real positive number, the vortex beam induces left-handed (negative) axial spin torque as the sphere shifts off-axially from the center of the beam. The results show that a non-diffracting non-paraxial fractional Bessel vortex beam is capable of inducing a spin reversal of an absorptive Rayleigh sphere placed arbitrarily in its path. Potential applications are yet to be explored in particle manipulation, rotation in optical tweezers, optical tractor beams, and the design of optically-engineered metamaterials to name a few areas.

  20. Orbital tori for non-axisymmetric galaxies

    NASA Astrophysics Data System (ADS)

    Binney, James

    2018-02-01

    Our Galaxy's bar makes the Galaxy's potential distinctly non-axisymmetric. All orbits are affected by non-axisymmetry, and significant numbers are qualitatively changed by being trapped at a resonance with the bar. Orbital tori are used to compute these effects. Thick-disc orbits are no less likely to be trapped by corotation or a Lindblad resonance than thin-disc orbits. Perturbation theory is used to create non-axisymmetric orbital tori from standard axisymmetric tori, and both trapped and untrapped orbits are recovered to surprising accuracy. Code is added to the TorusModeller library that makes it as easy to manipulate non-axisymmetric tori as axisymmetric ones. The augmented TorusModeller is used to compute the velocity structure of the solar neighbourhood for bars of different pattern speeds and a simple action-based distribution function. The technique developed here can be applied to any non-axisymmetric potential that is stationary in a rotating from - hence also to classical spiral structure.

  1. Comparative genome analysis of non-toxigenic non-O1 versus toxigenic O1 Vibrio cholerae

    PubMed Central

    Mukherjee, Munmun; Kakarla, Prathusha; Kumar, Sanath; Gonzalez, Esmeralda; Floyd, Jared T.; Inupakutika, Madhuri; Devireddy, Amith Reddy; Tirrell, Selena R.; Bruns, Merissa; He, Guixin; Lindquist, Ingrid E.; Sundararajan, Anitha; Schilkey, Faye D.; Mudge, Joann; Varela, Manuel F.

    2015-01-01

    Pathogenic strains of Vibrio cholerae are responsible for endemic and pandemic outbreaks of the disease cholera. The complete toxigenic mechanisms underlying virulence in Vibrio strains are poorly understood. The hypothesis of this work was that virulent versus non-virulent strains of V. cholerae harbor distinctive genomic elements that encode virulence. The purpose of this study was to elucidate genomic differences between the O1 serotypes and non-O1 V. cholerae PS15, a non-toxigenic strain, in order to identify novel genes potentially responsible for virulence. In this study, we compared the whole genome of the non-O1 PS15 strain to the whole genomes of toxigenic serotypes at the phylogenetic level, and found that the PS15 genome was distantly related to those of toxigenic V. cholerae. Thus we focused on a detailed gene comparison between PS15 and the distantly related O1 V. cholerae N16961. Based on sequence alignment we tentatively assigned chromosome numbers 1 and 2 to elements within the genome of non-O1 V. cholerae PS15. Further, we found that PS15 and O1 V. cholerae N16961 shared 98% identity and 766 genes, but of the genes present in N16961 that were missing in the non-O1 V. cholerae PS15 genome, 56 were predicted to encode not only for virulence–related genes (colonization, antimicrobial resistance, and regulation of persister cells) but also genes involved in the metabolic biosynthesis of lipids, nucleosides and sulfur compounds. Additionally, we found 113 genes unique to PS15 that were predicted to encode other properties related to virulence, disease, defense, membrane transport, and DNA metabolism. Here, we identified distinctive and novel genomic elements between O1 and non-O1 V. cholerae genomes as potential virulence factors and, thus, targets for future therapeutics. Modulation of such novel targets may eventually enhance eradication efforts of endemic and pandemic disease cholera in afflicted nations. PMID:25722857

  2. Comparative genome analysis of non-toxigenic non-O1 versus toxigenic O1 Vibrio cholerae.

    PubMed

    Mukherjee, Munmun; Kakarla, Prathusha; Kumar, Sanath; Gonzalez, Esmeralda; Floyd, Jared T; Inupakutika, Madhuri; Devireddy, Amith Reddy; Tirrell, Selena R; Bruns, Merissa; He, Guixin; Lindquist, Ingrid E; Sundararajan, Anitha; Schilkey, Faye D; Mudge, Joann; Varela, Manuel F

    Pathogenic strains of Vibrio cholerae are responsible for endemic and pandemic outbreaks of the disease cholera. The complete toxigenic mechanisms underlying virulence in Vibrio strains are poorly understood. The hypothesis of this work was that virulent versus non-virulent strains of V. cholerae harbor distinctive genomic elements that encode virulence. The purpose of this study was to elucidate genomic differences between the O1 serotypes and non-O1 V. cholerae PS15, a non-toxigenic strain, in order to identify novel genes potentially responsible for virulence. In this study, we compared the whole genome of the non-O1 PS15 strain to the whole genomes of toxigenic serotypes at the phylogenetic level, and found that the PS15 genome was distantly related to those of toxigenic V. cholerae . Thus we focused on a detailed gene comparison between PS15 and the distantly related O1 V. cholerae N16961. Based on sequence alignment we tentatively assigned chromosome numbers 1 and 2 to elements within the genome of non-O1 V. cholerae PS15. Further, we found that PS15 and O1 V. cholerae N16961 shared 98% identity and 766 genes, but of the genes present in N16961 that were missing in the non-O1 V. cholerae PS15 genome, 56 were predicted to encode not only for virulence-related genes (colonization, antimicrobial resistance, and regulation of persister cells) but also genes involved in the metabolic biosynthesis of lipids, nucleosides and sulfur compounds. Additionally, we found 113 genes unique to PS15 that were predicted to encode other properties related to virulence, disease, defense, membrane transport, and DNA metabolism. Here, we identified distinctive and novel genomic elements between O1 and non-O1 V. cholerae genomes as potential virulence factors and, thus, targets for future therapeutics. Modulation of such novel targets may eventually enhance eradication efforts of endemic and pandemic disease cholera in afflicted nations.

  3. Non-stoichiometric mixed-phase titania photocatalyst

    DOEpatents

    Chen, Le [Lakewood, CO; Gray, Kimberly A [Evanston, IL; Graham, Michael E [Evanston, IL

    2012-06-19

    A mixed anatase-rutile phase, non-stoichiometric titania photocatalyst material is a highly reactive and is a UV and visible light responsive photocastalyst in the as-deposited condition (i.e. without the need for a subsequent thermal treatment). The mixed phase, non-stoichiometric titania thin film material is non-stoichiometric in terms of its oxygen content such that the thin film material shows a marked red-shift in photoresponse.

  4. Eshelby's problem of non-elliptical inclusions

    NASA Astrophysics Data System (ADS)

    Zou, Wennan; He, Qichang; Huang, Mojia; Zheng, Quanshui

    2010-03-01

    The Eshelby problem consists in determining the strain field of an infinite linearly elastic homogeneous medium due to a uniform eigenstrain prescribed over a subdomain, called inclusion, of the medium. The salient feature of Eshelby's solution for an ellipsoidal inclusion is that the strain tensor field inside the latter is uniform. This uniformity has the important consequence that the solution to the fundamental problem of determination of the strain field in an infinite linearly elastic homogeneous medium containing an embedded ellipsoidal inhomogeneity and subjected to remote uniform loading can be readily deduced from Eshelby's solution for an ellipsoidal inclusion upon imposing appropriate uniform eigenstrains. Based on this result, most of the existing micromechanics schemes dedicated to estimating the effective properties of inhomogeneous materials have been nevertheless applied to a number of materials of practical interest where inhomogeneities are in reality non-ellipsoidal. Aiming to examine the validity of the ellipsoidal approximation of inhomogeneities underlying various micromechanics schemes, we first derive a new boundary integral expression for calculating Eshelby's tensor field (ETF) in the context of two-dimensional isotropic elasticity. The simple and compact structure of the new boundary integral expression leads us to obtain the explicit expressions of ETF and its average for a wide variety of non-elliptical inclusions including arbitrary polygonal ones and those characterized by the finite Laurent series. In light of these new analytical results, we show that: (i) the elliptical approximation to the average of ETF is valid for a convex non-elliptical inclusion but becomes inacceptable for a non-convex non-elliptical inclusion; (ii) in general, the Eshelby tensor field inside a non-elliptical inclusion is quite non-uniform and cannot be replaced by its average; (iii) the substitution of the generalized Eshelby tensor involved in various

  5. Non-invasive and Non-destructive Characterization of Tissue Engineered Constructs Using Ultrasound Imaging Technologies: A Review.

    PubMed

    Kim, Kang; Wagner, William R

    2016-03-01

    With the rapid expansion of biomaterial development and coupled efforts to translate such advances toward the clinic, non-invasive and non-destructive imaging tools to evaluate implants in situ in a timely manner are critically needed. The required multi-level information is comprehensive, including structural, mechanical, and biological changes such as scaffold degradation, mechanical strength, cell infiltration, extracellular matrix formation and vascularization to name a few. With its inherent advantages of non-invasiveness and non-destructiveness, ultrasound imaging can be an ideal tool for both preclinical and clinical uses. In this review, currently available ultrasound imaging technologies that have been applied in vitro and in vivo for tissue engineering and regenerative medicine are discussed and some new emerging ultrasound technologies and multi-modality approaches utilizing ultrasound are introduced.

  6. Non-invasive and non-destructive characterization of tissue engineered constructs using ultrasound imaging technologies: a review

    PubMed Central

    Kim, Kang; Wagner, William R.

    2015-01-01

    With the rapid expansion of biomaterial development and coupled efforts to translate such advances toward the clinic, non-invasive and non-destructive imaging tools to evaluate implants in situ in a timely manner are critically needed. The required multilevel information is comprehensive, including structural, mechanical, and biological changes such as scaffold degradation, mechanical strength, cell infiltration, extracellular matrix formation and vascularization to name a few. With its inherent advantages of non-invasiveness and non-destructiveness, ultrasound imaging can be an ideal tool for both preclinical and clinical uses. In this review, currently available ultrasound imaging technologies that have been applied in vitro and in vivo for tissue engineering and regenerative medicine are discussed and some new emerging ultrasound technologies and multi-modality approaches utilizing ultrasound are introduced. PMID:26518412

  7. Ecological impacts of non-native species: Chapter 2

    USGS Publications Warehouse

    Pilliod, David S.; Griffiths, R.A.; Kuzmin, S.L.; Heatwole, Harold; Wilkinson, John W.

    2012-01-01

    Non-native species are considered one of the greatest threats to freshwater biodiversity worldwide (Drake et al. 1989; Allen and Flecker 1993; Dudgeon et al. 2005). Some of the first hypotheses proposed to explain global patterns of amphibian declines included the effects of non-native species (Barinaga 1990; Blaustein and Wake 1990; Wake and Morowitz 1991). Evidence for the impact of non-native species on amphibians stems (1) from correlative research that relates the distribution or abundance of a species to that of a putative non-native species, and (2) from experimental tests of the effects of a non-native species on survival, growth, development or behaviour of a target species (Kats and Ferrer 2003). Over the past two decades, research on the effects of non-native species on amphibians has mostly focused on introduced aquatic predators, particularly fish. Recent research has shifted to more complex ecological relationships such as influences of sub-lethal stressors (e.g. contaminants) on the effects of non-native species (Linder et al. 2003; Sih et al. 2004), non-native species as vectors of disease (Daszak et al. 2004; Garner et al. 2006), hybridization between non-natives and native congeners (Riley et al. 2003; Storfer et al. 2004), and the alteration of food-webs by non-native species (Nystrom et al. 2001). Other research has examined the interaction of non-native species in terms of facilitation (i.e. one non-native enabling another to become established or spread) or the synergistic effects of multiple non-native species on native amphibians, the so-called invasional meltdown hypothesis (Simerloff and Von Holle 1999). Although there is evidence that some non-native species may interact (Ricciardi 2001), there has yet to be convincing evidence that such interactions have led to an accelerated increase in the number of non-native species and cumulative impacts are still uncertain (Simberloff 2006). Applied research on the control, eradication, and

  8. Non-reciprocity in nonlinear elastodynamics

    NASA Astrophysics Data System (ADS)

    Blanchard, Antoine; Sapsis, Themistoklis P.; Vakakis, Alexander F.

    2018-01-01

    Reciprocity is a fundamental property of linear time-invariant (LTI) acoustic waveguides governed by self-adjoint operators with symmetric Green's functions. The break of reciprocity in LTI elastodynamics is only possible through the break of time reversal symmetry on the micro-level, and this can be achieved by imposing external biases, adding nonlinearities or allowing for time-varying system properties. We present a Volterra-series based asymptotic analysis for studying spatial non-reciprocity in a class of one-dimensional (1D), time-invariant elastic systems with weak stiffness nonlinearities. We show that nonlinearity is neither necessary nor sufficient for breaking reciprocity in this class of systems; rather, it depends on the boundary conditions, the symmetries of the governing linear and nonlinear operators, and the choice of the spatial points where the non-reciprocity criterion is tested. Extension of the analysis to higher dimensions and time-varying systems is straightforward from a mathematical point of view (but not in terms of new non-reciprocal physical phenomena), whereas the connection of non-reciprocity and time irreversibility can be studied as well. Finally, we show that suitably defined non-reciprocity measures enable optimization, and can provide physical understanding of the nonlinear effects in the dynamics, enabling one to establish regimes of "maximum nonlinearity." We highlight the theoretical developments by means of a numerical example.

  9. Anomalously soft non-Euclidean spring

    NASA Astrophysics Data System (ADS)

    Levin, Ido; Sharon, Eran

    In this work we study the mechanical properties of a frustrated elastic ribbon spring - the non-Euclidean minimal spring. This spring belongs to the family of non-Euclidean plates: it has no spontaneous curvature, but its lateral intrinsic geometry is described by a non-Euclidean reference metric. The reference metric of the minimal spring is hyperbolic, and can be embedded as a minimal surface. We argue that the existence of a continuous set of such isometric minimal surfaces with different extensions leads to a complete degeneracy of the bulk elastic energy of the minimal spring under elongation. This degeneracy is removed only by boundary layer effects. As a result, the mechanical properties of the minimal spring are unusual: the spring is ultra-soft with rigidity that depends on the thickness, t , as t raise 0 . 7 ex 7 7 2 lower 0 . 7 ex 2, and does not explicitly depend on the ribbon's width. These predictions are confirmed by a numerical study of a constrained spring. This work is the first to address the unusual mechanical properties of constrained non-Euclidean elastic objects. We also present a novel experimental system that is capable of constructing such objects, along with many other non-Euclidean plates.

  10. Neoadjuvant chemotherapy response influences outcomes in non-colorectal, non-neuroendocrine liver metastases.

    PubMed

    Lucchese, A M; Kalil, A N; Ruiz, A; Karam, V; Ciacio, O; Pittau, G; Castaing, D; Cherqui, D; Sa Cunha, A; Vibert, E; Adam, R

    2018-06-12

    Indications for surgical resection of non-colorectal, non-neuroendocrine (NCNNE) liver metastases are unclear. This study analysed the influence of response to neoadjuvant chemotherapy and the presence of extrahepatic disease (EHD) on outcomes. Patients who underwent hepatic resection for NCNNE liver metastases and who received neoadjuvant chemotherapy at a single centre between 1982 and 2016 were analysed retrospectively. Patients were classified as having no EHD, controlled EHD or non-controlled EHD. Hepatic resection was performed in 199 patients (81·2 per cent) after partial or complete response to chemotherapy or disease stabilization, and 46 patients (18·8 per cent) after tumour progression. Patients with progressive disease after chemotherapy had worse overall survival than those without (23 versus 50·4 per cent at 5 years; P = 0·004). Median survival was 63·6 (range 31·1-94·8) months for patients without EHD, 34·8 (19·2-49·2) months for those with controlled EHD and 7·2 (1·2-13·2) months for patients with non-controlled EHD (P = 0·004). In multivariable analysis, EHD (P = 0·004), response to chemotherapy (P = 0·004) and resection margins (P = 0·002) were all independent predictors of overall survival, regardless of primary tumour site. The prognosis of patients with NCNNE liver metastases is influenced by preoperative chemotherapy and resectability. © 2018 BJS Society Ltd Published by John Wiley & Sons Ltd.

  11. Non Celiac Gluten Sensitivity.

    PubMed

    Bardella, Maria Teresa; Elli, Luca; Ferretti, Francesca

    2016-12-01

    A new syndrome responding to gluten-free diet and defined non-celiac gluten sensitivity entered the spectrum of gluten-related disorders, together with celiac disease and wheat allergy. However, its definition, prevalence, diagnosis, pathogenesis, treatment, and follow up are still controversial. The purpose of the review is to summarize the evidence and problems emerging from the current literature. Direct implication of gluten in the onset of symptoms is often unproved as a low fermentable oligo-, di- and mono-saccharides and polyols diet or other components of cereals as wheat amylase trypsin inhibitor could be similarly involved. To date, no specific biomarkers or histological abnormalities confirm diagnosis, and only the self-reported response to gluten-free diet as well as a positive double blind placebo-gluten challenge characterizes these non-celiac, non-wheat allergic patients. Critical revision of published studies can offer practical indications in approaching this clinical topic and useful suggestions to standardize scientific researches.

  12. Non-collinear valve actuator

    NASA Technical Reports Server (NTRS)

    Richard, James A. (Inventor)

    2012-01-01

    A non-collinear valve actuator includes a primary actuating system and a return spring system with each applying forces to a linkage system in order to regulate the flow of a quarter-turn valve. The primary actuating system and return spring system are positioned non-collinearly, which simply means the primary actuating system and return spring system are not in line with each other. By positioning the primary actuating system and return spring system in this manner, the primary actuating system can undergo a larger stroke while the return spring system experiences significantly less displacement. This allows the length of the return spring to be reduced due to the minimization of displacement thereby reducing the weight of the return spring system. By allowing the primary actuating system to undergo longer strokes, the weight of the primary actuating system may also be reduced. Accordingly, the weight of the non-collinear valve actuator is reduced.

  13. Non-Coalescence in Microgravity: Science and Technology

    NASA Technical Reports Server (NTRS)

    Neitzel, G. Paul; Nagy, P.; Carnasciali, M. I.; DellAversana, P.; Vetrano, M. R.; Chen, J.-C.; Kuo, C. W.

    2002-01-01

    In this project we examine non-coalescence and non-wetting phenomena driven by either thermocapillary convection or forced motion of one surface relative to the other. In both cases, the non-coalescence or non-wetting is enabled by the existence of a lubricating layer of gas that exists to keep the two surfaces in question from coming into contact with one another. Recent progress has been made on several fronts: 1) measurement of the vibrational modes of pinned droplets; 2) development of an apparatus for the measurement of the frictional forces associated with a non-wetting droplet sliding over a solid surface; 3) measurements of the failure modes for non-wetting droplets and the influence of static electric charge on failure-, and 4) numerical simulation of a two-dimensional non-wetting droplet revealing a possible explanation for why the phenomenon has not been able to be observed using water as the droplet liquid. Issue 1) above is of relevance to the use of non-wetting droplets as positioning mechanisms and vibration dampers in a microgravity environment; issue 2) relates to the use of non-wetting droplets as nearly 'frictionless' bearings in low-load applications. Understanding of the failure modes identified in 3) is of importance to any potential application and the numerical simulations conducted under 4) allow us to obtain information about these systems that is currently not available through experimentation Each of these topics will be discussed briefly during the presentation.

  14. Risk factors for testicular cancer--differences between pure non-seminoma and mixed seminoma/non-seminoma?

    PubMed

    Aschim, E L; Haugen, T B; Tretli, S; Daltveit, A K; Grotmol, T

    2006-08-01

    The origin of testicular germ cell cancer (TGCC) is believed to be carcinoma in situ cells developed in utero. Clinically, TGCCs are divided into two major histological groups, seminomas and non-seminomas, where the latter group includes non-seminomatous TGCCs with seminomatous components (mixed S/NS TGCC). Recent studies, however, have suggested that non-seminomas and mixed S/NS TGCCs could have certain differences in aetiology, and in this study the TGCCs were divided into three, rather than the conventional two histological groups. A large case-control study was undertaken on data on all live-born boys registered in the Medical Birth Registry of Norway during the period 1967-1998 (n=961 396). Among these were 1087 TGCC cases registered in the Cancer Registry of Norway until February 2004. We found several risk factors for TGCC, including low parity, low gestational age, epilepsy and retained placenta. Several of the variables studied seemed to be risk factors for specific histological groups, e.g. parity 0 vs. 2 and low gestational age being associated with increased risk of non-seminomas, but not of mixed S/NS TGCC, and low maternal age being associated with increased risk of mixed S/NS TGCC, but not of non-seminomatous TGCC. Therefore, our results might suggest that non-seminomas and mixed S/NS TGCCs have partially different risk factors, whose associations may be obscured by combining these two histological groups. The histological groups were not significantly different, however. Most of our findings on risk factors for TGCC are in agreement with at least some previous studies. An unexplainable exception is low birth weight being associated with reduced risk of TGCC in our study.

  15. Non-equilibrium Green's functions method: Non-trivial and disordered leads

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    He, Yu, E-mail: heyuyhe@gmail.com; Wang, Yu; Klimeck, Gerhard

    2014-11-24

    The non-equilibrium Green's function algorithm requires contact self-energies to model charge injection and extraction. All existing approaches assume infinitely periodic leads attached to a possibly quite complex device. This contradicts today's realistic devices in which contacts are spatially inhomogeneous, chemically disordered, and impacting the overall device characteristics. This work extends the complex absorbing potentials method for arbitrary, ideal, or non-ideal leads in atomistic tight binding representation. The algorithm is demonstrated on a Si nanowire with periodic leads, a graphene nanoribbon with trumpet shape leads, and devices with leads of randomly alloyed Si{sub 0.5}Ge{sub 0.5}. It is found that alloy randomnessmore » in the leads can reduce the predicted ON-state current of Si{sub 0.5}Ge{sub 0.5} transistors by 45% compared to conventional lead methods.« less

  16. Aerospace Applications of Non-Equilibrium Plasma

    NASA Technical Reports Server (NTRS)

    Blankson, Isaiah M.

    2016-01-01

    Nonequilibrium plasma/non-thermal plasma/cold plasmas are being used in a wide range of new applications in aeronautics, active flow control, heat transfer reduction, plasma-assisted ignition and combustion, noise suppression, and power generation. Industrial applications may be found in pollution control, materials surface treatment, and water purification. In order for these plasma processes to become practical, efficient means of ionization are necessary. A primary challenge for these applications is to create a desired non-equilibrium plasma in air by preventing the discharge from transitioning into an arc. Of particular interest is the impact on simulations and experimental data with and without detailed consideration of non-equilibrium effects, and the consequences of neglecting non-equilibrium. This presentation will provide an assessment of the presence and influence of non-equilibrium phenomena for various aerospace needs and applications. Specific examples to be considered will include the forward energy deposition of laser-induced non-equilibrium plasmoids for sonic boom mitigation, weakly ionized flows obtained from pulsed nanosecond discharges for an annular Hall type MHD generator duct for turbojet energy bypass, and fundamental mechanisms affecting the design and operation of novel plasma-assisted reactive systems in dielectric liquids (water purification, in-pipe modification of fuels, etc.).

  17. Non-commutative methods in quantum mechanics

    NASA Astrophysics Data System (ADS)

    Millard, Andrew Clive

    1997-09-01

    Non-commutativity appears in physics almost hand in hand with quantum mechanics. Non-commuting operators corresponding to observables lead to Heisenberg's Uncertainty Principle, which is often used as a prime example of how quantum mechanics transcends 'common sense', while the operators that generate a symmetry group are usually given in terms of their commutation relations. This thesis discusses a number of new developments which go beyond the usual stopping point of non-commuting quantities as matrices with complex elements. Chapter 2 shows how certain generalisations of quantum mechanics, from using complex numbers to using other (often non-commutative) algebras, can still be written as linear systems with symplectic phase flows. Chapter 3 deals with Adler's trace dynamics, a non-linear graded generalisation of Hamiltonian dynamics with supersymmetry applications, where the phase space coordinates are (generally non-commuting) operators, and reports on aspects of a demonstration that the statistical averages of the dynamical variables obey the rules of complex quantum field theory. The last two chapters discuss specific aspects of quaternionic quantum mechanics. Chapter 4 reports a generalised projective representation theory and presents a structure theorem that categorises quaternionic projective representations. Chapter 5 deals with a generalisation of the coherent states formalism and examines how it may be applied to two commonly used groups.

  18. Examples for Non-Ideal Solution Thermodynamics Study

    ERIC Educational Resources Information Center

    David, Carl W.

    2004-01-01

    A mathematical model of a non-ideal solution is presented, where it is shown how and where the non-ideality manifests itself in the standard thermodynamics tableau. Examples related to the non-ideal solution thermodynamics study are also included.

  19. Non-autoimmune primary hypothyroidism in diabetic and non-diabetic chronic renal dysfunction.

    PubMed

    Bando, Y; Ushiogi, Y; Okafuji, K; Toya, D; Tanaka, N; Miura, S

    2002-11-01

    The aim of this study was to investigate the frequency and mechanisms of hypothyroidism observed in diabetic patients with advanced diabetic nephropathy, including outcomes of management for this condition. A controlled study was designed using 32 diabetic and 31 non-diabetic patients not receiving hemodialysis or continuous ambulatory peritoneal dialysis (CAPD) who excreted mean urinary protein greater than 0.5 g/day examined on three consecutive days during admission to our hospital. Thyroid hormones in both serum and urine, anti-thyroid antibodies, renal function and iodine concentrations in serum were measured during admission in all patients included. In particular, in patients who showed overt hypothyroidism, further studies including large-needle biopsies of the thyroid and iodine-perchlorate discharge tests were performed. All patients in the two groups revealed negative antithyroid antibody titers, and the mean serum total iodine levels did not significantly differ between the two groups. Mean serum FT4 levels significantly decreased, and the TSH level was significantly elevated in the diabetic group compared to those in the non-diabetic group (p < 0.005, p < 0.02, respectively). The frequency of overt hypothyroidism in the diabetic group (22%; 7/32) was significantly higher (p < 0.05) than that in the non-diabetic group (3.2%; 1/31). The daily urinary thyroid hormone excretion in both groups did not show any significant correlation with serum thyroid hormone levels. Seven patients who revealed overt hypothyroidism in the diabetic group showed elevated serum total iodine levels during hypothyroidal status, ranging between 177 and 561 microg/l. Also, the iodine-perchlorate discharge tests carried out in six of these patients all showed a positive discharge. After management based on iodine restriction, normalization of serum thyroid hormone levels in accordance with definite decreases in the serum total iodine level was achieved, accompanied by a

  20. Non-functional tricuspid valve disease.

    PubMed

    Adler, Dale S

    2017-05-01

    Only 75% of severe tricuspid regurgitation is classified as functional, or related primarily to pulmonary hypertension, right ventricular dysfunction, or a combination of both. Non-functional tricuspid regurgitation occurs when there is damage to the tricuspid leaflets, chordae, papillary muscles, or annulus, independent of right ventricular dysfunction or pulmonary hypertension. The entities that cause non-functional tricuspid regurgitation include rheumatic and myxomatous disease, acquired and genetic connective tissue disorders, endocarditis, sarcoid, pacing, RV biopsy, blunt trauma, radiation, carcinoid, ergot alkaloids, dopamine agonists, fenfluramine, cardiac tumors, atrial fibrillation, and congenital malformations. Over time, severe tricuspid regurgitation that is initially non-functional, can blend into functional tricuspid regurgitation, related to progressive right ventricular dysfunction. Symptoms and signs, including a falling right ventricular ejection fraction, cardiac cirrhosis, ascites, esophageal varices, and anasarca, may occur insidiously and late, but are associated with substantial morbidity and mortality. Attempted valve repair or replacement at late stages carries a high mortality. Crucial to following patients with severe non-functional tricuspid regurgitation is attention to echo quantification of the tricuspid regurgitation and right ventricular function, patient symptoms, and the physical examination.

  1. Molecular evidence of viral DNA in non-small cell lung cancer and non-neoplastic lung

    DOE PAGES

    Robinson, Lary A.; Jaing, Crystal J.; Campbell, Christine Pierce; ...

    2016-07-14

    Although ~20% of human cancers are caused by microorganisms, only suspicion exists for a microbial cause of lung cancer. Potential infectious agents were investigated in non-small cell lung cancer (NSCLC) and non-neoplastic lung. Seventy NSCLC tumours (33 squamous cell carcinomas, 17 adenocarcinomas, 10 adenocarcinomas with lepidic spread, and 10 oligometastases) and 10 non-neoplastic lung specimens were evaluated for molecular evidence of microorganisms. Tissues were subjected to the Lawrence Livermore Microbial Detection Array, an oncovirus panel of the International Agency for Research on Cancer, and human papillomavirus (HPV) genotyping. Associations were examined between microbial prevalence, clinical characteristics, and p16 and EGFRmore » expression. Retroviral DNA was observed in 85% squamous cell carcinomas, 47% adenocarcinomas, and 10% adenocarcinomas with lepidic spread. Human papillomavirus DNA was found in 69% of squamous cell carcinomas with 30% containing high-risk HPV types. No significant viral DNA was detected in non-neoplastic lung. Patients with tumours containing viral DNA experienced improved long-term survival compared with patients with viral DNA-negative tumours. Lastly, most squamous cell carcinomas and adenocarcinomas contained retroviral DNA and one-third of squamous cell carcinomas contained high-risk HPV DNA. Viral DNA was absent in non-neoplastic lung. Trial results encourage further study of the viral contribution to lung carcinogenesis.« less

  2. Molecular evidence of viral DNA in non-small cell lung cancer and non-neoplastic lung

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Robinson, Lary A.; Jaing, Crystal J.; Campbell, Christine Pierce

    Although ~20% of human cancers are caused by microorganisms, only suspicion exists for a microbial cause of lung cancer. Potential infectious agents were investigated in non-small cell lung cancer (NSCLC) and non-neoplastic lung. Seventy NSCLC tumours (33 squamous cell carcinomas, 17 adenocarcinomas, 10 adenocarcinomas with lepidic spread, and 10 oligometastases) and 10 non-neoplastic lung specimens were evaluated for molecular evidence of microorganisms. Tissues were subjected to the Lawrence Livermore Microbial Detection Array, an oncovirus panel of the International Agency for Research on Cancer, and human papillomavirus (HPV) genotyping. Associations were examined between microbial prevalence, clinical characteristics, and p16 and EGFRmore » expression. Retroviral DNA was observed in 85% squamous cell carcinomas, 47% adenocarcinomas, and 10% adenocarcinomas with lepidic spread. Human papillomavirus DNA was found in 69% of squamous cell carcinomas with 30% containing high-risk HPV types. No significant viral DNA was detected in non-neoplastic lung. Patients with tumours containing viral DNA experienced improved long-term survival compared with patients with viral DNA-negative tumours. Lastly, most squamous cell carcinomas and adenocarcinomas contained retroviral DNA and one-third of squamous cell carcinomas contained high-risk HPV DNA. Viral DNA was absent in non-neoplastic lung. Trial results encourage further study of the viral contribution to lung carcinogenesis.« less

  3. Lessons from non-canonical splicing

    PubMed Central

    Ule, Jernej

    2016-01-01

    Recent improvements in experimental and computational techniques used to study the transcriptome have enabled an unprecedented view of RNA processing, revealing many previously unknown non-canonical splicing events. This includes cryptic events located far from the currently annotated exons, and unconventional splicing mechanisms that have important roles in regulating gene expression. These non-canonical splicing events are a major source of newly emerging transcripts during evolution, especially when they involve sequences derived from transposable elements. They are therefore under precise regulation and quality control, which minimises their potential to disrupt gene expression. While non-canonical splicing can lead to aberrant transcripts that cause many diseases, we also explain how it can be exploited for new therapeutic strategies. PMID:27240813

  4. A novel Trojan-horse targeting strategy to reduce the non-specific uptake of nanocarriers by non-cancerous cells.

    PubMed

    Shen, Zheyu; Wu, Hao; Yang, Sugeun; Ma, Xuehua; Li, Zihou; Tan, Mingqian; Wu, Aiguo

    2015-11-01

    One big challenge with active targeting of nanocarriers is non-specific binding between targeting molecules and non-target moieties expressed on non-cancerous cells, which leads to non-specific uptake of nanocarriers by non-cancerous cells. Here, we propose a novel Trojan-horse targeting strategy to hide or expose the targeting molecules of nanocarriers on-demand. The non-specific uptake by non-cancerous cells can be reduced because the targeting molecules are hidden in hydrophilic polymers. The nanocarriers are still actively targetable to cancer cells because the targeting molecules can be exposed on-demand at tumor regions. Typically, Fe3O4 nanocrystals (FN) as magnetic resonance imaging (MRI) contrast agents were encapsulated into albumin nanoparticles (AN), and then folic acid (FA) and pH-sensitive polymers (PP) were grafted onto the surface of AN-FN to construct PP-FA-AN-FN nanoparticles. Fourier transform infrared spectroscopy (FT-IR), dynamic light scattering (DLS), transmission electron microscope (TEM) and gel permeation chromatography (GPC) results confirm successful construction of PP-FA-AN-FN. According to difference of nanoparticle-cellular uptake between pH 7.4 and 5.5, the weight ratio of conjugated PP to nanoparticle FA-AN-FN (i.e. graft density) and the molecular weight of PP (i.e. graft length) are optimized to be 1.32 and 5.7 kDa, respectively. In vitro studies confirm that the PP can hide ligand FA to prevent it from binding to cells with FRα at pH 7.4 and shrink to expose FA at pH 5.5. In vivo studies demonstrate that our Trojan-horse targeting strategy can reduce the non-specific uptake of the PP-FA-AN-FN by non-cancerous cells. Therefore, our PP-FA-AN-FN might be used as an accurately targeted MRI contrast agent. Copyright © 2015 Elsevier Ltd. All rights reserved.

  5. Detection of ctx gene positive non-O1/non-O139 V. cholerae in shrimp aquaculture environments.

    PubMed

    Madhusudana, Rao B; Surendran, P K

    2013-06-01

    Water and post-larvae samples from black tiger (Penaeus monodon) shrimp hatcheries; pond water, pond sediment and shrimp from aquaculture farms were screened for the presence of V. cholerae. A V. cholerae-duplex PCR method was developed by utilizing V. cholerae species specific sodB primers and ctxAB genes specific primers. Incidence of V. cholerae was not observed in shrimp hatchery samples but was noticed in aquaculture samples. The incidence of V. cholerae was higher in pond water (7.6%) than in pond sediment (5.2%). Shrimp head (3.6%) portion had relatively higher incidence than shrimp muscle (1.6%). All the V. cholerae isolates (n = 42) belonged to non-O1/non-O139 serogroup, of which 7% of the V. cholerae isolates were potentially cholera-toxigenic (ctx positive). All the ctx positive V. cholerae (n = 3) were isolated from the pond water. Since, cholera toxin (CT) is the major contributing factor for cholera gravis, it is proposed that the mere presence of non-O1/non-O139 V. cholerae need not be the biohazard criterion in cultured black tiger shrimp but only the presence of ctx carrying non-O1/non-O139 V. cholerae may be considered as potential public health risk.

  6. Assessing the extent of non-aggressive cancer in clinically detected stage I non-small cell lung cancer.

    PubMed

    Kale, Minal S; Sigel, Keith; Mhango, Grace; Wisnivesky, Juan P

    2018-05-01

    Overdiagnosis among clinically detected lung cancers likely consists of cases that are non-aggressive and slowly progressive and will never disseminate, cause symptoms or be a threat to a subject's survival, even if untreated. In this study, we estimate the prevalence of non-aggressive lung cancers from a large, population-based cancer registry. We identified individuals ≥65 years with histologically confirmed, untreated stage I non-small cell lung cancers (NSCLCs) from the Surveillance, Epidemiology, and End Results-Medicare registry. We estimated the rate of non-aggressive lung cancers by determining the point at which the cumulative lung cancer-specific survival curve no longer changed (ie, the slope approaches zero). At this point, there are no additional deaths due to progressive lung cancer observed among untreated patients after adjusting for deaths from competing risks (these long-term survivors can be considered 'non-aggressive cases). The overall rate of non-aggressive cancers among 2197 clinically detected cases of untreated stage I NSCLC was 2.4%, 95% CI: 1.0% to 3.8%. The rate of non-aggressive cancer was 1.9% (95% CI: 0.0% to 4.9%) for women and 2.4% (95% CI: 0.7% to 4.1%) for men (p=0.84). When stratifying by tumour size, non-aggressive cancer rates were 10.2% (95% CI: 0.0% to 29.3%), 2.1% (95% CI: 0.0% to 9.2%), 4.9% (95% CI: 0.0% to 10.3%), 1.8% (95% CI: 0.0% to 5.2%) and 0.0% (95% CI: 0.0% to 1.0%) for tumour sizes <15 mm, 15-24 mm, 25-34 mm, 35-44 mm and ≥45 mm, respectively. In comparison with the smallest tumour sizes (<15 mm), the rates of non-aggressive cancers were not statistically significantly different for tumour sizes 15-24 mm (p=0.36), 25-34 mm (p=0.57), 35-44 mm (p=0.38) and tumour sizes >45 mm (p=0.30). We found relatively low rates of non-aggressive cancers among clinically detected, stage I NSCLC regardless of sex or size. Our findings suggest that most clinically diagnosed early stage cancers should be treated with

  7. 40 CFR 156.85 - Non-target organisms.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Non-target organisms. 156.85 Section 156.85 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS... Non-target organisms. (a) Requirement. Where a hazard exists to non-target organisms, EPA may require...

  8. 40 CFR 156.85 - Non-target organisms.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 24 2011-07-01 2011-07-01 false Non-target organisms. 156.85 Section 156.85 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS... Non-target organisms. (a) Requirement. Where a hazard exists to non-target organisms, EPA may require...

  9. Risky car following in abstinent users of MDMA.

    PubMed

    Dastrup, Elizabeth; Lees, Monica N; Bechara, Antoine; Dawson, Jeffrey D; Rizzo, Matthew

    2010-05-01

    Ecstasy (MDMA) use raises concerns because of its association with risky driving. We evaluated driving performance and risk taking in abstinent recreational MDMA users in a simulated car following task that required continuous attention and vigilance. Drivers were asked to follow two car lengths behind a lead vehicle (LV). Three sinusoids generated unpredictable LV velocity changes. Drivers could mitigate risk by following further behind the erratic LV. From vehicle trajectory data we performed a Fourier analysis to derive measures of coherence, gain, and delay. These measures and headway distance were compared between the different groups. All MDMA drivers met coherence criteria indicating cooperation in the car following task. They matched periodic changes in LV velocity similar to controls (abstinent THC users, abstinent alcohol users, and non-drug users), militating against worse vigilance. While all participants traveled approximately 55 mph (89 kph), the MDMA drivers followed 64 m closer to the LV and demonstrated 1.04 s shorter delays to LV velocity changes than other driver groups. The simulated car following task safely discriminated between driving behavior in abstinent MDMA users and controls. Abstinent MDMA users do not perform worse than controls, but may assume extra risk. The control theory framework used in this study revealed behaviors that might not otherwise be evident. Copyright (c) 2009 Elsevier Ltd. All rights reserved.

  10. Municipal solid waste management challenges in developing countries--Kenyan case study.

    PubMed

    Henry, Rotich K; Yongsheng, Zhao; Jun, Dong

    2006-01-01

    This paper provides an overview of the state of municipal solid waste management (MSWM) by local authorities in Kenya as a case study of a low-income developing country. Approaches of possible solutions that can be undertaken to improve municipal solid waste (MSW) services are discussed. Poor economic growth (1.1% in 1993) has resulted in an increase in the poverty level which presently stands at 56%. Migration from the rural areas to the urban areas has resulted in unplanned settlements in suburban areas accommodating about 60% of the urban population on only 5% urban land area. Political interference also hampers smooth running of local authorities. Vulnerability of pollution of surface and groundwater is high because local authorities rarely considered environmental impact in siting MSW disposal sites. Illegal dumping of MSW on the river banks or on the roadside poses environmental and economic threats on nearby properties. Poor servicing of MSW collection vehicles, poor state of infrastructure and the lack of adequate funding militate against optimization of MSW disposal service. The rural economy needs to be improved if rural-urban migration is to be managed. Involvement of stakeholders is important to achieve any meaningful and sustainable MSWM. The role of the informal sector through community-based organizations (CBOs), Non-Governmental Organizations (NGOs) and the private sector in offering solutions towards improvement of MSWM also is explored.

  11. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Henry, Rotich K.; Zhao Yongsheng; Dong Jun

    This paper provides an overview of the state of municipal solid waste management (MSWM) by local authorities in Kenya as a case study of a low-income developing country. Approaches of possible solutions that can be undertaken to improve municipal solid waste (MSW) services are discussed. Poor economic growth (1.1% in 1993) has resulted in an increase in the poverty level which presently stands at 56%. Migration from the rural areas to the urban areas has resulted in unplanned settlements in suburban areas accommodating about 60% of the urban population on only 5% urban land area. Political interference also hampers smoothmore » running of local authorities. Vulnerability of pollution of surface and groundwater is high because local authorities rarely considered environmental impact in siting MSW disposal sites. Illegal dumping of MSW on the river banks or on the roadside poses environmental and economic threats on nearby properties. Poor servicing of MSW collection vehicles, poor state of infrastructure and the lack of adequate funding militate against optimization of MSW disposal service. The rural economy needs to be improved if rural-urban migration is to be managed. Involvement of stakeholders is important to achieve any meaningful and sustainable MSWM. The role of the informal sector through community-based organizations (CBOs), Non-Governmental Organizations (NGOs) and the private sector in offering solutions towards improvement of MSWM also is explored.« less

  12. Non-planar chemical preconcentrator

    DOEpatents

    Manginell, Ronald P [Albuquerque, NM; Adkins, Douglas R [Albuquerque, NM; Sokolowski, Sara S [Albuquerque, NM; Lewis, Patrick R [Albuquerque, NM

    2006-10-10

    A non-planar chemical preconcentrator comprises a high-surface area, low mass, three-dimensional, flow-through sorption support structure that can be coated or packed with a sorptive material. The sorptive material can collect and concentrate a chemical analyte from a fluid stream and rapidly release it as a very narrow temporal plug for improved separations in a microanalytical system. The non-planar chemical preconcentrator retains most of the thermal and fabrication benefits of a planar preconcentrator, but has improved ruggedness and uptake, while reducing sorptive coating concerns and extending the range of collectible analytes.

  13. Constraining generalized non-local cosmology from Noether symmetries

    NASA Astrophysics Data System (ADS)

    Bahamonde, Sebastian; Capozziello, Salvatore; Dialektopoulos, Konstantinos F.

    2017-11-01

    We study a generalized non-local theory of gravity which, in specific limits, can become either the curvature non-local or teleparallel non-local theory. Using the Noether symmetry approach, we find that the coupling functions coming from the non-local terms are constrained to be either exponential or linear in form. It is well known that in some non-local theories, a certain kind of exponential non-local couplings is needed in order to achieve a renormalizable theory. In this paper, we explicitly show that this kind of coupling does not need to be introduced by hand, instead, it appears naturally from the symmetries of the Lagrangian in flat Friedmann-Robertson-Walker cosmology. Finally, we find de Sitter and power-law cosmological solutions for different non-local theories. The symmetries for the generalized non-local theory are also found and some cosmological solutions are also achieved using the full theory.

  14. Constraining generalized non-local cosmology from Noether symmetries.

    PubMed

    Bahamonde, Sebastian; Capozziello, Salvatore; Dialektopoulos, Konstantinos F

    2017-01-01

    We study a generalized non-local theory of gravity which, in specific limits, can become either the curvature non-local or teleparallel non-local theory. Using the Noether symmetry approach, we find that the coupling functions coming from the non-local terms are constrained to be either exponential or linear in form. It is well known that in some non-local theories, a certain kind of exponential non-local couplings is needed in order to achieve a renormalizable theory. In this paper, we explicitly show that this kind of coupling does not need to be introduced by hand, instead, it appears naturally from the symmetries of the Lagrangian in flat Friedmann-Robertson-Walker cosmology. Finally, we find de Sitter and power-law cosmological solutions for different non-local theories. The symmetries for the generalized non-local theory are also found and some cosmological solutions are also achieved using the full theory.

  15. A disease-specific quality of life instrument for non-alcoholic fatty liver disease and non-alcoholic steatohepatitis: CLDQ-NAFLD.

    PubMed

    Younossi, Zobair M; Stepanova, Maria; Henry, Linda; Racila, Andrei; Lam, Brian; Pham, Huong T; Hunt, Sharon

    2017-08-01

    Non-alcoholic fatty liver disease and non-alcoholic steatohepatitis are the most common causes of chronic liver disease with known negative impact on patients' health-related quality of life. Our aim was to validate a disease-specific health-related quality of life instrument useful for efficacy trials involving patients with non-alcoholic fatty liver disease and non-alcoholic steatohepatitis. From a long item selection questionnaire, we selected relevant items which, by factor analysis, were grouped into domains constituting Chronic Liver Disease Questionnaire-Non-Alcoholic Fatty Liver Disease version. The developed instrument was subjected to internal validity, test-retest reliability and construct validity assessment using standard methods. For development of the Chronic Liver Disease Questionnaire-Non-Alcoholic Fatty Liver Disease version instrument, a 75-item-long item selection questionnaire was administered to 25 patients with non-alcoholic fatty liver disease. After item reduction, factor analysis found that 98.7% of variance in the remaining items would be explained by six factors. Thus, the resulting Chronic Liver Disease Questionnaire-Non-Alcoholic Fatty Liver Disease version instrument had 36 items grouped into six domains: Abdominal Symptoms, Activity, Emotional, Fatigue, Systemic Symptoms, and Worry. The independent validation group included another 104 patients with non-alcoholic fatty liver disease. The Cronbach's alphas of 0.74-0.90 suggested good to excellent internal consistency of the domains. Furthermore, the presence of obesity and history of depression were discriminated best by Chronic Liver Disease Questionnaire-Non-Alcoholic Fatty Liver Disease version scores (P<.05). The domains' correlations with the most relevant domains of Short Form-36 exceeded 0.70. Test-retest reliability in a subgroup of patients (N=27) demonstrated no significant within-patient variability with multiple administrations (all median differences were zero, all P>.15

  16. Non-Infectious Meningitis

    MedlinePlus

    ... Links Vaccine Schedules Preteen & Teen Vaccines Meningococcal Disease Sepsis Non-Infectious Meningitis Recommend on Facebook Tweet Share ... Links Vaccine Schedules Preteen & Teen Vaccines Meningococcal Disease Sepsis File Formats Help: How do I view different ...

  17. A Geoscience Workforce Model for Non-Geoscience and Non-Traditional STEM Students

    NASA Astrophysics Data System (ADS)

    Liou-Mark, J.; Blake, R.; Norouzi, H.; Vladutescu, D. V.; Yuen-Lau, L.

    2016-12-01

    The Summit on the Future of Geoscience Undergraduate Education has recently identified key professional skills, competencies, and conceptual understanding necessary in the development of undergraduate geoscience students (American Geosciences Institute, 2015). Through a comprehensive study involving a diverse range of the geoscience academic and employer community, the following professional scientist skills were rated highly important: 1) critical thinking/problem solving skills; 2) effective communication; 3) ability to access and integrate information; 4) strong quantitative skills; and 5) ability to work in interdisciplinary/cross cultural teams. Based on the findings of the study above, the New York City College of Technology (City Tech) has created a one-year intensive training program that focusses on the development of technical and non-technical geoscience skills for non-geoscience, non-traditional STEM students. Although City Tech does not offer geoscience degrees, the primary goal of the program is to create an unconventional pathway for under-represented minority STEM students to enter, participate, and compete in the geoscience workforce. The selected cohort of STEM students engage in year-round activities that include a geoscience course, enrichment training workshops, networking sessions, leadership development, research experiences, and summer internships at federal, local, and private geoscience facilities. These carefully designed programmatic elements provide both the geoscience knowledge and the non-technical professional skills that are essential for the geoscience workforce. Moreover, by executing this alternate, robust geoscience workforce model that attracts and prepares underrepresented minorities for geoscience careers, this unique pathway opens another corridor that helps to ameliorate the dire plight of the geoscience workforce shortage. This project is supported by NSF IUSE GEOPATH Grant # 1540721.

  18. 7 CFR 993.6 - Non-French prunes.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Non-French prunes. 993.6 Section 993.6 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... Order Regulating Handling Definitions § 993.6 Non-French prunes. Non-French prunes means prunes commonly...

  19. 7 CFR 993.6 - Non-French prunes.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 8 2011-01-01 2011-01-01 false Non-French prunes. 993.6 Section 993.6 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... Order Regulating Handling Definitions § 993.6 Non-French prunes. Non-French prunes means prunes commonly...

  20. Assessment of preparation time with fully-liquid versus non-fully liquid paediatric hexavalent vaccines. A time and motion study.

    PubMed

    De Coster, Ilse; Fournie, Xavier; Faure, Céline; Ziani, Eddy; Nicolas, Laurence; Soubeyrand, Benoit; Van Damme, Pierre

    2015-07-31

    Simplified vaccine preparation steps would save time and reduce potential immunisation errors. The aim of the study was to assess vaccine preparation time with fully-liquid hexavalent vaccine (DTaP-IPV-HB-PRP-T, Sanofi Pasteur MSD) versus non-fully liquid hexavalent vaccine that needs reconstitution (DTPa-HBV-IPV/Hib, GlaxoSmithKline Biologicals). Ninety-six Health Care Professionals (HCPs) participated in a randomised, cross-over, open-label, time and motion study in Belgium (2014). HCPs prepared each vaccine in a cross-over manner with a wash-out period of 3-5min. An independent nurse assessed preparation time and immunisation errors by systematic review of the videos. HCPs satisfaction and preference were evaluated by a self-administered questionnaire. Average preparation time was 36s for the fully-liquid vaccine and 70.5s for the non-fully liquid vaccine. The time saved using the fully-liquid vaccine was 34.5s (p≤0.001). On 192 preparations, 57 immunisation errors occurred: 47 in the non-fully liquid vaccine group (including one missing reconstitution of Hib component), 10 in the fully-liquid vaccine group. 71.9% of HCPs were very or somewhat satisfied with the ease of handling of both vaccines; 66.7% and 67.7% were very or somewhat satisfied with speed of preparation in the fully-liquid vaccine and the non-fully liquid vaccine groups, respectively. Almost all HCPs (97.6%) stated they would prefer the use of the fully-liquid vaccine in their daily practice. Preparation of a fully-liquid hexavalent vaccine can be completed in half the time necessary to prepare a non-fully liquid vaccine. The simplicity of the fully-liquid hexavalent vaccine preparation helps optimise reduction of immunisation errors. Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.

  1. Non-firearm-related homicide, New Mexico, 2001-3.

    PubMed

    Kazerouni, N Neely; Shah, N; Lathrop, S; Landen, M G

    2009-10-01

    New Mexico (NM) has the highest rate of non-firearm-related homicide in the USA and ranks 20th in firearm-related homicides. Because non-firearm-related homicides are inadequately described in the literature, characterisation of non-firearm-related homicide victims will enhance efforts to reduce homicides. Homicide victims were identified through the Office of the Medical Investigator. Age-specific and age-adjusted homicide death rates were calculated for 2001-3 by sex and race/ethnicity, and associations between covariates and non-firearm-related homicide were measured. Non-firearm-related homicides comprised 33% of US homicide victims, 47% of NM homicide victims, and 74% of NM American Indian (AI) homicide victims. Of 212 NM non-firearm-related homicide victims, 37% had been beaten, 32% had been stabbed, and 12% had been strangled. Females comprised 30% of non-firearm-related homicide victims and 18% of firearm-related homicide victims. A blood alcohol concentration (BAC) >or=0.08 mg/dl was detected among 43% of non-firearm-related (61% of AI) and 33% of firearm-related (50% of AI) homicide victims. Non-firearm-related homicide rates were highest among AI men aged 25-34 years (31/100,000). Non-firearm-related homicide victims were more likely than firearm-related victims to be AI (adjusted odds ratio (AOR) 4.20; 95% CI 2.16 to 8.16) and female (AOR 2.05; 95% CI 1.27 to 3.31), and to have had a BAC >or=0.08 mg/dl (AOR 1.65; 95% CI 1.08 to 2.52). Homicide-prevention efforts among AIs in NM should focus on non-firearm-related homicides. The association between excessive drinking and non-firearm-related homicide should be further characterised. Continued surveillance for non-firearm-related homicides will assist these efforts.

  2. Regulatory Scientific Advice on Non-Inferiority Drug Trials

    PubMed Central

    Knol, Mirjam J.; Klungel, Olaf H.; Gispen-De Wied, Christine C.; de Boer, Antonius; Hoes, Arno W.; Leufkens, Hubert G.; Mantel-Teeuwisse, Aukje K.

    2013-01-01

    The active-controlled trial with a non-inferiority design has gained popularity in recent years. However, non-inferiority trials present some methodological challenges, especially in determining the non-inferiority margin. Regulatory guidelines provide some general statements on how a non-inferiority trial should be conducted. Moreover, in a scientific advice procedure, regulators give companies the opportunity to discuss critical trial issues prior to the start of the trial. The aim of this study was to identify potential issues that may benefit from more explicit guidance by regulators. To achieve this, we collected and analyzed questions about non-inferiority trials posed by applicants for scientific advice in Europe in 2008 and 2009, as well as the responses given by the European Medicines Agency (EMA). In our analysis we included 156 final letters of advice from 2008 and 2009, addressed to 94 different applicants (manufacturers). Our analysis yielded two major findings: (1) applicants frequently asked questions ‘whether’ and ‘how’ to conduct a non-inferiority trial, 26% and 74%, respectively, and (2) the EMA regulators seem mainly concerned about the choice of the non-inferiority margin in non-inferiority trials (36% of total regulatory answers). In 40% of the answers, the EMA recommended using a stricter margin, and in 10% of the answers regarding non-inferiority margins, the EMA questioned the justification of the proposed non-inferiority margin. We conclude that there are still difficulties in selecting the appropriate methodology for non-inferiority trials. Straightforward and harmonized guidance regarding non-inferiority trials is required, for example on whether it is necessary to conduct such a trial and how the non-inferiority margin is determined. It is unlikely that regulatory guidelines can cover all therapeutic areas; therefore, in some cases regulatory scientific advice may be used as an opportunity for tailored advice. PMID:24040346

  3. [Not Available].

    PubMed

    Ronsin, F

    1979-01-01

    Malthusianism in France in the years before the 1st world war was quickly transformed by the socialist ideology and presented to the working class as a revolutionary theory which might help the masses toward the goal of social revolution. However, the original appeal to moral restraint only (late marriage, sexual abstinence) in avoiding unwanted pregnancies was refused, and contraception was advertised vigorously. The 1st militant neomalthusian organization, The Malthusian League, was created in 1877, and was ideologically linked to anglo-saxon social reformism. At the beginning ot the 20th century Malthusianism in France began to assume a different character under the influence of a leading militant revolutionary, Paul Robin, who emphasized the Malthusian doctrine as an indispensable strategic tool of the proletariat's success, when coupled with better education. The Malthusian League published 2 magazines, Regeneration, and, later, Le Malthusien. Most French Neomalthusians belonged to the anarchist movement and gathered around its publication, Libertaire. However, the so called pure anarchists and the communists were against it, and strong opposition also came from the labor unions and from at least some of the socialist press. In 1911 the Federation of Neomalthusian Working Groups was founded; within it socialist groups with different ideologies debated the Malthusian theory. Notwithstanding the Federation's efforts to link Neomalthusianism with the workers' movement, this link was never really established. The Federation had to fight against the dominant bourgeois ideology, against other revolutionary groups, and against those who wanted to save France from the danger of underpopulation and the immigration of increasing numbers of workers from less civilized countries. Birthrate began declining in France at the end of the 18th century, but the greatest decline began between 1890-1900. It is very difficult to determine whether Neomalthusianism affected the

  4. Storming wombs and Waco: how the anti-abortion and militia movements converge.

    PubMed

    Dubowski, S

    1996-10-01

    This study describes how violent anti-abortion militancy and "Christian Patriot" militia (unregulated private army) activity in the US converge. "Christian Patriots" reject all laws except the US Constitution and its first ten amendments and claim that Anglo-Saxon Christian men are the only true citizens. The convergence of this group with anti-abortion groups can be seen by the fact that militia leaders have been arrested for blocking women's health centers, and anti-abortion leaders have been linked to militia and white supremacist groups. This anti-abortion/militia link has a great potential for violence. The two groups also rallied around standoffs between federal agents and extremist groups such as that which occurred in Waco, Texas. The mainstreaming of militias is seen to be a relatively new phenomenon, and people like Larry Pratt, executive director of Gun Owners of America, are identified as "almost a shadow congressman" in the US. Pratt's organization contributed to 46 Republican campaigns in 1994 and bankrolled Operation Rescue when federal agents seized the organization's bank accounts for failure to pay a court-ordered fine. A chart illustrates the names, state, primary affiliation, secondary affiliations, and actions or statements of 22 of the individuals involved in militias and anti-abortion efforts. It is also noted that anti-abortion militants use private Christian schools as vehicles to spread their views, and the increasing threat to abortion providers of militia violence is reviewed. It is concluded that abortion is a "bridge" issue which allows religious political extremist factions to recruit members. Abortion is being used as a catalyst in the struggle of these white supremacists to replace democracy with a theocracy which seeks to enforce idiosyncratic versions of God's law.

  5. Antiabortion violence: causes and effects.

    PubMed

    Radford, B; Shaw, G

    1993-01-01

    Most antiabortion groups objected peacefully to the US Supreme Court decision granting women access to abortion by lobbying, demonstrating, and writing letters. Some groups reacted violently. In 1984, violent acts had climbed to 18 bombings and 6 acts of arson directed against abortion providers. They dropped in 1988-1990 and rose again in 1992-1993. The far rights' disapproval of the Reagan and Bush Administrations' inability to make abortion illegal accounts for these increased acts of violence. The violent antiabortion groups interpreted Reagan's failure to stop the continuing violence as approval of their methods. A former Catholic seminarian, Joseph Scheidler, called for a militant effort to end abortion, thereby unleashing the militant, violent antiabortion movement. He led local grassroots groups nationwide to accomplish the Year of Pain and Fear he called for in his book. Antiabortion zealots understand and use the potency of language. The dehumanize abortion providers. They suggest that followers pray for death or destruction. Their rhetoric of hatred motivates persons to perform violent acts. Little difference exists between clinic blockaders and clinic bombers/arsonists. Antiabortion zealots tend to be financial and social drifters escaping a past of drinking or drugs and from very dysfunctional families. Antiabortion violence has ushered in a new wave--murder of a provider. Abortion providers have adapted to lie with threats, jeering, and bricks thrown through windows. Even though abortion seekers fear personal injury, they fear even more harassment and invasion of privacy. Their tactics have reduced women's access to abortion care. Abortion providers operate in just 17% of US counties. When zealots spew hatred on families, however, providers often stop performing abortions. Nevertheless, communities are starting to stand up to the reactionaries. Neighbors, patients, businesses, and other physicians in Montana supported a clinic after a violent act

  6. BLACK PRETERM BIRTH RISK IN NON-BLACK NEIGHBORHOODS: EFFECTS OF HISPANIC, ASIAN, AND NON-HISPANIC WHITE ETHNIC DENSITIES

    PubMed Central

    Mason, Susan M.; Kaufman, Jay S.; Daniels, Julie L.; Emch, Michael E.; Hogan, Vijaya K.; Savitz, David A.

    2013-01-01

    Purpose Studies of ethnic density and health in the United States have documented poorer health outcomes in black compared to non-black neighborhoods, but few studies have considered the identities of the non-black populations. Methods New York City birth records from 1995 through 2003 and a spatial measure of ethnic density were used to examine preterm birth risks among non-Hispanic black women associated with non-Hispanic white, Hispanic, Asian, and non-Hispanic black neighborhood densities. Logistic regression models were used to estimate the effect on black preterm birth risks of replacing white neighbors with Hispanic, Asian, and black neighbors. Risk differences were computed for changes from the 10th to the 90th percentiles of ethnic density. Results Increasing Hispanic density was associated with reduced preterm birth risks among non-Hispanic black women, especially if the black women were foreign-born (RD=−19.1 per 1,000 births; 95% CI: −28.6, −9.5). Estimates for increasing Asian density were null. Increasing black density was associated with increasing black preterm birth risk, with a threshold at higher levels of black density. Conclusions The low risks of preterm birth among foreign-born non-Hispanic black women in majority-Hispanic neighborhoods may be related to protective psychosocial or nutritional factors in Hispanic neighborhoods. PMID:21737050

  7. Non-hard sphere thermodynamic perturbation theory.

    PubMed

    Zhou, Shiqi

    2011-08-21

    A non-hard sphere (HS) perturbation scheme, recently advanced by the present author, is elaborated for several technical matters, which are key mathematical details for implementation of the non-HS perturbation scheme in a coupling parameter expansion (CPE) thermodynamic perturbation framework. NVT-Monte Carlo simulation is carried out for a generalized Lennard-Jones (LJ) 2n-n potential to obtain routine thermodynamic quantities such as excess internal energy, pressure, excess chemical potential, excess Helmholtz free energy, and excess constant volume heat capacity. Then, these new simulation data, and available simulation data in literatures about a hard core attractive Yukawa fluid and a Sutherland fluid, are used to test the non-HS CPE 3rd-order thermodynamic perturbation theory (TPT) and give a comparison between the non-HS CPE 3rd-order TPT and other theoretical approaches. It is indicated that the non-HS CPE 3rd-order TPT is superior to other traditional TPT such as van der Waals/HS (vdW/HS), perturbation theory 2 (PT2)/HS, and vdW/Yukawa (vdW/Y) theory or analytical equation of state such as mean spherical approximation (MSA)-equation of state and is at least comparable to several currently the most accurate Ornstein-Zernike integral equation theories. It is discovered that three technical issues, i.e., opening up new bridge function approximation for the reference potential, choosing proper reference potential, and/or using proper thermodynamic route for calculation of f(ex-ref), chiefly decide the quality of the non-HS CPE TPT. Considering that the non-HS perturbation scheme applies for a wide variety of model fluids, and its implementation in the CPE thermodynamic perturbation framework is amenable to high-order truncation, the non-HS CPE 3rd-order or higher order TPT will be more promising once the above-mentioned three technological advances are established. © 2011 American Institute of Physics

  8. Rubinstein-Taybi syndrome predisposing to non-WNT, non-SHH, group 3 medulloblastoma.

    PubMed

    Bourdeaut, Franck; Miquel, Catherine; Richer, Wilfrid; Grill, Jacques; Zerah, Michel; Grison, Camille; Pierron, Gaelle; Amiel, Jeanne; Krucker, Clementine; Radvanyi, Francois; Brugieres, Laurence; Delattre, Olivier

    2014-02-01

    Medulloblastomas (MB) are classified in four subgroups: the well defined WNT and Sonic Hedgehog (SHH) subgroups, and the less defined groups 3 and 4. They occasionally occur in the context of a cancer predisposition syndrome. While germline APC mutations predispose to WNT MB, germline mutations in SUFU, PTCH1, and TP53 predispose to SHH tumors. We report on a child with a Rubinstein-Taybi syndrome (RTS) due to a germline deletion in CREBBP, who developed a MB. Biological profilings demonstrate that this tumor belongs to the group 3. RTS may therefore be the first predisposition syndrome identified for non-WNT/non-SHH MB. © 2013 Wiley Periodicals, Inc.

  9. Non-invasive and non-destructive measurements of confluence in cultured adherent cell lines.

    PubMed

    Busschots, Steven; O'Toole, Sharon; O'Leary, John J; Stordal, Britta

    2015-01-01

    Many protocols used for measuring the growth of adherent monolayer cells in vitro are invasive, destructive and do not allow for the continued, undisturbed growth of cells within flasks. Protocols often use indirect methods for measuring proliferation. Microscopy techniques can analyse cell proliferation in a non-invasive or non-destructive manner but often use expensive equipment and software algorithms. In this method images of cells within flasks are captured by photographing under a standard inverted phase contract light microscope using a digital camera with a camera lens adaptor. Images are analysed for confluence using ImageJ freeware resulting in a measure of confluence known as an Area Fraction (AF) output. An example of the AF method in use on OVCAR8 and UPN251 cell lines is included. •Measurements of confluence from growing adherent cell lines in cell culture flasks is obtained in a non-invasive, non-destructive, label-free manner.•The technique is quick, affordable and eliminates sample manipulation.•The technique provides an objective, consistent measure of when cells reach confluence and is highly correlated to manual counting with a haemocytometer. The average correlation co-efficient from a Spearman correlation (n = 3) was 0.99 ± 0.008 for OVCAR8 (p = 0.01) and 0.99 ± 0.01 for UPN251 (p = 0.01) cell lines.

  10. Performance of non-invasive models of fibrosis in predicting mild to moderate fibrosis in patients with non-alcoholic fatty liver disease.

    PubMed

    Siddiqui, Mohammad S; Patidar, Kavish R; Boyett, Sherry; Luketic, Velimir A; Puri, Puneet; Sanyal, Arun J

    2016-04-01

    In non-alcoholic fatty liver disease, presence of fibrosis is predictive of long-term liver-related complications. Currently, there are no reliable and non-invasive means of quantifying fibrosis in those with non-alcoholic fatty liver disease. Therefore, we aimed to evaluate the performance of a panel of non-invasive models in predicting fibrosis in non-alcoholic fatty liver disease. The accuracy of FibroMeter non-alcoholic fatty liver disease, fibrosis 4 and four other non-invasive models in predicting fibrosis in those with biopsy proven non-alcoholic fatty liver disease was compared. These models were constructed post hoc in patients who had necessary clinical information collected within 2 months of a liver biopsy. The areas under receiver operating characteristics curves were compared for each model using Delong analysis. Optimum cut-off for each model and fibrosis stage were calculated using the Youden index. The area under receiver operating characteristics curves for F ≥ 1 fibrosis for fibrosis 4 and FibroMeter non-alcoholic fatty liver disease was 0.821 and 0.801 respectively. For F ≥ 3, the area under receiver operating characteristics curves was 0.866 for fibrosis 4 and 0.862 for FibroMeter non-alcoholic fatty liver disease. Delong analysis showed the area under receiver operating characteristics curves was statistically different for fibrosis 4 and FibroMeter non-alcoholic fatty liver disease compared with BARD, BAAT and aspartate aminotransferase:alanine aminotransferase ratio for F ≥ 1 and F ≥ 3. Area under receiver operating characteristics curves were significantly different for fibrosis 4 and FibroMeter non-alcoholic fatty liver disease for F ≥ 3 compared with non-alcoholic fatty liver disease fibrosis score. At a fixed sensitivity of 90%, FibroMeter non-alcoholic fatty liver disease had the highest specificity for F ≥ 1 (52.4%) and F ≥ 3 (63.8%). In contrast, at a fixed specificity of 90%, fibrosis 4 outperformed other models with a

  11. Native plant diversity increases herbivory to non-natives

    PubMed Central

    Pearse, Ian S.; Hipp, Andrew L.

    2014-01-01

    There is often an inverse relationship between the diversity of a plant community and the invasibility of that community by non-native plants. Native herbivores that colonize novel plants may contribute to diversity–invasibility relationships by limiting the relative success of non-native plants. Here, we show that, in large collections of non-native oak trees at sites across the USA, non-native oaks introduced to regions with greater oak species richness accumulated greater leaf damage than in regions with low oak richness. Underlying this trend was the ability of herbivores to exploit non-native plants that were close relatives to their native host. In diverse oak communities, non-native trees were on average more closely related to native trees and received greater leaf damage than those in depauperate oak communities. Because insect herbivores colonize non-native plants that are similar to their native hosts, in communities with greater native plant diversity, non-natives experience greater herbivory. PMID:25232143

  12. 42 CFR 81.30 - Non-radiogenic cancers.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Non-radiogenic cancers. 81.30 Section 81.30 Public... Causation § 81.30 Non-radiogenic cancers. The following cancers are considered non-radiogenic for the... cancers: (a) Chronic lymphocytic leukemia (ICD-9 code: 204.1) (b) [Reserved] ...

  13. 12 CFR 621.31 - Non-audit services.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 6 2011-01-01 2011-01-01 false Non-audit services. 621.31 Section 621.31 Banks and Banking FARM CREDIT ADMINISTRATION FARM CREDIT SYSTEM ACCOUNTING AND REPORTING REQUIREMENTS Auditor Independence § 621.31 Non-audit services. Non-audit services are any professional services...

  14. 12 CFR 621.31 - Non-audit services.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 7 2013-01-01 2013-01-01 false Non-audit services. 621.31 Section 621.31 Banks and Banking FARM CREDIT ADMINISTRATION FARM CREDIT SYSTEM ACCOUNTING AND REPORTING REQUIREMENTS Auditor Independence § 621.31 Non-audit services. Non-audit services are any professional services...

  15. 12 CFR 621.31 - Non-audit services.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 7 2012-01-01 2012-01-01 false Non-audit services. 621.31 Section 621.31 Banks and Banking FARM CREDIT ADMINISTRATION FARM CREDIT SYSTEM ACCOUNTING AND REPORTING REQUIREMENTS Auditor Independence § 621.31 Non-audit services. Non-audit services are any professional services...

  16. 12 CFR 621.31 - Non-audit services.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 7 2014-01-01 2014-01-01 false Non-audit services. 621.31 Section 621.31 Banks and Banking FARM CREDIT ADMINISTRATION FARM CREDIT SYSTEM ACCOUNTING AND REPORTING REQUIREMENTS Auditor Independence § 621.31 Non-audit services. Non-audit services are any professional services...

  17. 49 CFR 523.5 - Non-passenger automobile.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 6 2011-10-01 2011-10-01 false Non-passenger automobile. 523.5 Section 523.5... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION VEHICLE CLASSIFICATION § 523.5 Non-passenger automobile. A non-passenger automobile means an automobile that is not a passenger automobile or a work truck and includes...

  18. 49 CFR 523.5 - Non-passenger automobile.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 6 2010-10-01 2010-10-01 false Non-passenger automobile. 523.5 Section 523.5... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION VEHICLE CLASSIFICATION § 523.5 Non-passenger automobile. A non-passenger automobile means an automobile that is not a passenger automobile or a work truck and includes...

  19. 49 CFR 523.5 - Non-passenger automobile.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 6 2014-10-01 2014-10-01 false Non-passenger automobile. 523.5 Section 523.5... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION VEHICLE CLASSIFICATION § 523.5 Non-passenger automobile. A non-passenger automobile means an automobile that is not a passenger automobile or a work truck and includes...

  20. 49 CFR 523.5 - Non-passenger automobile.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 6 2013-10-01 2013-10-01 false Non-passenger automobile. 523.5 Section 523.5... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION VEHICLE CLASSIFICATION § 523.5 Non-passenger automobile. A non-passenger automobile means an automobile that is not a passenger automobile or a work truck and includes...

  1. 49 CFR 523.5 - Non-passenger automobile.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 6 2012-10-01 2012-10-01 false Non-passenger automobile. 523.5 Section 523.5... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION VEHICLE CLASSIFICATION § 523.5 Non-passenger automobile. A non-passenger automobile means an automobile that is not a passenger automobile or a work truck and includes...

  2. 42 CFR 81.30 - Non-radiogenic cancers.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Non-radiogenic cancers. 81.30 Section 81.30 Public... Causation § 81.30 Non-radiogenic cancers. The following cancers are considered non-radiogenic for the... cancers: (a) Chronic lymphocytic leukemia (ICD-9 code: 204.1) (b) [Reserved] ...

  3. 46 CFR 249.10 - Non-discrimination policy.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Non-discrimination policy. 249.10 Section 249.10... OPERATORS APPROVAL OF UNDERWRITERS FOR MARINE HULL INSURANCE § 249.10 Non-discrimination policy. To administer effectively the policy regarding non-discrimination against U.S. insurers in other countries, as...

  4. Landsat non-US standard catalog

    NASA Technical Reports Server (NTRS)

    1975-01-01

    The Non-U.S. Standard Catalog lists Non-U.S. imagery acquired by Landsat 1 and 2 which was processed and input to the data files during the referenced month. Data, such as date acquired, cloud cover and image quality are given for each scene. The microfilm roll and frame on which the scene may be found are also given.

  5. Non-equilibrium dog-flea model

    NASA Astrophysics Data System (ADS)

    Ackerson, Bruce J.

    2017-11-01

    We develop the open dog-flea model to serve as a check of proposed non-equilibrium theories of statistical mechanics. The model is developed in detail. Then it is applied to four recent models for non-equilibrium statistical mechanics. Comparison of the dog-flea solution with these different models allows checking claims and giving a concrete example of the theoretical models.

  6. A Dream of Yukawa — Non-Local Fields out of Non-Commutative Spacetime —

    NASA Astrophysics Data System (ADS)

    Naka, Shigefumi; Toyoda, Haruki; Takanashi, Takahiro; Umezawa, Eizo

    The coordinates of κ-Minkowski spacetime form Lie algebraic elements, in which time and space coordinates do not commute in spite of that space coordinates commute each other. The non-commutativity is realized by a Planck-length-scale constant κ - 1( ne 0), which is a universal constant other than the light velocity under the κ-Poincare transformation. Such a non-commutative structure can be realized by SO(1,4) generators in dS4 spacetime. In this work, we try to construct a κ-Minkowski like spacetime with commutative 4-dimensional spacetime based on Adsn+1 spacetime. Another aim of this work is to study invariant wave equations in this spacetime from the viewpoint of non-local field theory by H. Yukawa, who expected to realize elementary particle theories without divergence according to this viewpoint.

  7. Arabidopsis non-host resistance to powdery mildews.

    PubMed

    Lipka, Ulrike; Fuchs, Rene; Lipka, Volker

    2008-08-01

    Immunity of an entire plant species against all genetic variants of a particular parasite is referred to as non-host resistance. Although non-host resistance represents the most common and durable form of plant resistance in nature, it has thus far been poorly understood at the molecular level. Recently, novel model systems have established the first mechanistic insights. The genetic dissection of Arabidopsis non-host resistance to non-adapted biotrophic powdery mildew fungi provided evidence for functionally redundant but operationally distinct pre- and post-invasion immune responses. Conceptually, these complex and successive defence mechanisms explain the durable and robust nature of non-host resistance. Pathogen lifestyle and infection biology, ecological parameters and the evolutionary relationship of the interaction partners determine differences and commonalities in other model systems.

  8. Modelling non-hydrostatic processes in sill regions

    NASA Astrophysics Data System (ADS)

    Souza, A.; Xing, J.; Davies, A.; Berntsen, J.

    2007-12-01

    We use a non-hydrostatic model to compute tidally induced flow and mixing in the region of bottom topography representing the sill at the entrance to Loch Etive (Scotland). This site is chosen since detailed measurements were recently made there. With non-hydrostatic dynamics in the model our results showed that the model could reproduce the observed flow characteristics, e.g., hydraulic transition, flow separation and internal waves. However, when calculations were performed using the model in the hydrostatic form, significant artificial convective mixing occurred. This influenced the computed temperature and flow field. We will discuss in detail the effects of non-hydrostatic dynamics on flow over the sill, especially investigate non-linear and non-hydrostatic contributions to modelled internal waves and internal wave energy fluxes.

  9. Non-Coalescence Effects in Microgravity

    NASA Technical Reports Server (NTRS)

    Neitzel, G. Paul

    1997-01-01

    Non-coalescence of two bodies of the same liquid and the suppression of contact between liquid drops and solid surfaces is being studied through a pair of parallel investigations being conducted at the Georgia Institute of Technology and the Microgravity Research and Support (MARS) Center in Naples, Italy. Both non-coalescence and contact suppression are achieved by exploiting the mechanism of thermocapillary convection to drive a lubricating film of surrounding gas (air) into the space between the two liquid free surfaces (non-coalescence) or between the drop free surface and the solid (contact suppression). Experiments performed to date include flow visualization experiments in both axisymmetric and (nearly) two-dimensional geometries and quantitative measurements of film thickness in the contact-suppression case in both geometries.

  10. Galaxy bias and primordial non-Gaussianity

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Assassi, Valentin; Baumann, Daniel; Schmidt, Fabian, E-mail: assassi@ias.edu, E-mail: D.D.Baumann@uva.nl, E-mail: fabians@MPA-Garching.MPG.DE

    2015-12-01

    We present a systematic study of galaxy biasing in the presence of primordial non-Gaussianity. For a large class of non-Gaussian initial conditions, we define a general bias expansion and prove that it is closed under renormalization, thereby showing that the basis of operators in the expansion is complete. We then study the effects of primordial non-Gaussianity on the statistics of galaxies. We show that the equivalence principle enforces a relation between the scale-dependent bias in the galaxy power spectrum and that in the dipolar part of the bispectrum. This provides a powerful consistency check to confirm the primordial origin ofmore » any observed scale-dependent bias. Finally, we also discuss the imprints of anisotropic non-Gaussianity as motivated by recent studies of higher-spin fields during inflation.« less

  11. Flat bands in lattices with non-Hermitian coupling

    NASA Astrophysics Data System (ADS)

    Leykam, Daniel; Flach, Sergej; Chong, Y. D.

    2017-08-01

    We study non-Hermitian photonic lattices that exhibit competition between conservative and non-Hermitian (gain/loss) couplings. A bipartite sublattice symmetry enforces the existence of non-Hermitian flat bands, which are typically embedded in an auxiliary dispersive band and give rise to nondiffracting "compact localized states". Band crossings take the form of non-Hermitian degeneracies known as exceptional points. Excitations of the lattice can produce either diffracting or amplifying behaviors. If the non-Hermitian coupling is fine-tuned to generate an effective π flux, the lattice spectrum becomes completely flat, a non-Hermitian analog of Aharonov-Bohm caging in which the magnetic field is replaced by balanced gain and loss. When the effective flux is zero, the non-Hermitian band crossing points give rise to asymmetric diffraction and anomalous linear amplification.

  12. Non-transfusion-dependent thalassemias

    PubMed Central

    Musallam, Khaled M.; Rivella, Stefano; Vichinsky, Elliott; Rachmilewitz, Eliezer A.

    2013-01-01

    Non-transfusion-dependent thalassemias include a variety of phenotypes that, unlike patients with beta (β)-thalassemia major, do not require regular transfusion therapy for survival. The most commonly investigated forms are β-thalassemia intermedia, hemoglobin E/β-thalassemia, and α-thalassemia intermedia (hemoglobin H disease). However, transfusion-independence in such patients is not without side effects. Ineffective erythropoiesis and peripheral hemolysis, the hallmarks of disease process, lead to a variety of subsequent pathophysiologies including iron overload and hypercoagulability that ultimately lead to a number of serious clinical morbidities. Thus, prompt and accurate diagnosis of non-transfusion-dependent thalassemia is essential to ensure early intervention. Although several management options are currently available, the need to develop more novel therapeutics is justified by recent advances in our understanding of the mechanisms of disease. Such efforts require wide international collaboration, especially since non-transfusion-dependent thalassemias are no longer bound to low- and middle-income countries but have spread to large multiethnic cities in Europe and the Americas due to continued migration. PMID:23729725

  13. 28 CFR 570.42 - Non-medical escorted trips.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Non-medical escorted trips. 570.42... RELEASE COMMUNITY PROGRAMS Escorted Trips § 570.42 Non-medical escorted trips. (a) Non-medical escorted trips allow an inmate to leave the institution under staff escort for approved, non-medical reasons...

  14. 48 CFR 252.227-7000 - Non-estoppel.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Non-estoppel. 252.227-7000... Clauses 252.227-7000 Non-estoppel. As prescribed at 227.7009-1, insert the following clause in patent releases, license agreements, and assignments: Non-Estoppel (OCT 1966) The Government reserves the right at...

  15. 16 CFR 260.10 - Non-toxic claims.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... pose any risk to humans or the environment, including household pets. If the cleaning product poses no... implication, that a product, package, or service is non-toxic. Non-toxic claims should be clearly and... product, package, or service is non-toxic both for humans and for the environment generally. Therefore...

  16. 16 CFR 260.10 - Non-toxic claims.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... pose any risk to humans or the environment, including household pets. If the cleaning product poses no... implication, that a product, package, or service is non-toxic. Non-toxic claims should be clearly and... product, package, or service is non-toxic both for humans and for the environment generally. Therefore...

  17. [A case-control study: association between oral hygiene and oral cancer in non-smoking and non-drinking women].

    PubMed

    Wu, J F; Lin, L S; Chen, F; Liu, F Q; Huang, J F; Yan, L J; Liu, F P; Qiu, Y; Zheng, X Y; Cai, L; He, B C

    2017-08-06

    Objective: To evaluate the influence of oral hygiene on risk of oral cancer in non-smoking and non-drinking women. Methods: From September 2010 to February 2016, 242 non-smoking and non-drinking female patients with pathologically confirmed oral cancer were recruited in a hospital of Fuzhou, and another 856 non-smoking and non-drinking healthy women from health examination center in the same hospital were selected as control group. Five oral hygiene related variables including the frequency of teeth brushing, number of teeth lost, poor prosthesis, regular dental visits and recurrent dental ulceration were used to develop oral hygiene index model. Unconditional logistic regression was used to calculate odds ratios ( OR ) and 95% confidence intervals (95 %CI ). The area under the receiver operating characteristic curve (AUROC) was used to evaluate the predictability of the oral hygiene index model. Multivariate logistic regression model was used to analyze the association between oral hygiene index and the incidence of oral cancer. Results: Teeth brushing <2 twice daily, teeth lost ≥5, poor prosthesis, no regular dental visits, recurrent dental ulceration were risk factors for the incidence of oral cancer in non-smoking and non-drinking women, the corresponding OR (95 %CI ) were 1.50 (1.08-2.09), 1.81 (1.15-2.85), 1.51 (1.03-2.23), 1.73 (1.15-2.59), 7.30 (4.00-13.30), respectively. The AUROC of the oral hygiene index model was 0.705 9, indicating a high predictability. Multivariate logistic regression showed that the oral hygiene index was associated with risk of oral cancer. The higher the score, the higher risk was observed. The corresponding OR (95 %CI ) of oral hygiene index scores (score 1, score 2, score 3, score 4-5) were 2.51 (0.84-7.53), 4.68 (1.59-13.71), 6.47 (2.18-19.25), 15.29 (5.08-45.99), respectively. Conclusion: Oral hygiene could influence the incidence of oral cancer in non-smoking and non-drinking women, and oral hygiene index has a certain

  18. Non-B DB v2.0: a database of predicted non-B DNA-forming motifs and its associated tools.

    PubMed

    Cer, Regina Z; Donohue, Duncan E; Mudunuri, Uma S; Temiz, Nuri A; Loss, Michael A; Starner, Nathan J; Halusa, Goran N; Volfovsky, Natalia; Yi, Ming; Luke, Brian T; Bacolla, Albino; Collins, Jack R; Stephens, Robert M

    2013-01-01

    The non-B DB, available at http://nonb.abcc.ncifcrf.gov, catalogs predicted non-B DNA-forming sequence motifs, including Z-DNA, G-quadruplex, A-phased repeats, inverted repeats, mirror repeats, direct repeats and their corresponding subsets: cruciforms, triplexes and slipped structures, in several genomes. Version 2.0 of the database revises and re-implements the motif discovery algorithms to better align with accepted definitions and thresholds for motifs, expands the non-B DNA-forming motifs coverage by including short tandem repeats and adds key visualization tools to compare motif locations relative to other genomic annotations. Non-B DB v2.0 extends the ability for comparative genomics by including re-annotation of the five organisms reported in non-B DB v1.0, human, chimpanzee, dog, macaque and mouse, and adds seven additional organisms: orangutan, rat, cow, pig, horse, platypus and Arabidopsis thaliana. Additionally, the non-B DB v2.0 provides an overall improved graphical user interface and faster query performance.

  19. 7 CFR 993.108 - Non-human consumption outlet.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Non-human consumption outlet. 993.108 Section 993.108... CALIFORNIA Administrative Rules and Regulations Definitions § 993.108 Non-human consumption outlet. Non-human... feed, or other product for non-human use, who has established, to the satisfaction of the committee...

  20. 7 CFR 993.108 - Non-human consumption outlet.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 8 2011-01-01 2011-01-01 false Non-human consumption outlet. 993.108 Section 993.108... CALIFORNIA Administrative Rules and Regulations Definitions § 993.108 Non-human consumption outlet. Non-human... feed, or other product for non-human use, who has established, to the satisfaction of the committee...

  1. 7 CFR 993.108 - Non-human consumption outlet.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 8 2013-01-01 2013-01-01 false Non-human consumption outlet. 993.108 Section 993.108... CALIFORNIA Administrative Rules and Regulations Definitions § 993.108 Non-human consumption outlet. Non-human... feed, or other product for non-human use, who has established, to the satisfaction of the committee...

  2. Non-functional tricuspid valve disease

    PubMed Central

    2017-01-01

    Only 75% of severe tricuspid regurgitation is classified as functional, or related primarily to pulmonary hypertension, right ventricular dysfunction, or a combination of both. Non-functional tricuspid regurgitation occurs when there is damage to the tricuspid leaflets, chordae, papillary muscles, or annulus, independent of right ventricular dysfunction or pulmonary hypertension. The entities that cause non-functional tricuspid regurgitation include rheumatic and myxomatous disease, acquired and genetic connective tissue disorders, endocarditis, sarcoid, pacing, RV biopsy, blunt trauma, radiation, carcinoid, ergot alkaloids, dopamine agonists, fenfluramine, cardiac tumors, atrial fibrillation, and congenital malformations. Over time, severe tricuspid regurgitation that is initially non-functional, can blend into functional tricuspid regurgitation, related to progressive right ventricular dysfunction. Symptoms and signs, including a falling right ventricular ejection fraction, cardiac cirrhosis, ascites, esophageal varices, and anasarca, may occur insidiously and late, but are associated with substantial morbidity and mortality. Attempted valve repair or replacement at late stages carries a high mortality. Crucial to following patients with severe non-functional tricuspid regurgitation is attention to echo quantification of the tricuspid regurgitation and right ventricular function, patient symptoms, and the physical examination. PMID:28706863

  3. Anomalously Soft Non-Euclidean Springs

    NASA Astrophysics Data System (ADS)

    Levin, Ido; Sharon, Eran

    2016-01-01

    In this work we study the mechanical properties of a frustrated elastic ribbon spring—the non-Euclidean minimal spring. This spring belongs to the family of non-Euclidean plates: it has no spontaneous curvature, but its lateral intrinsic geometry is described by a non-Euclidean reference metric. The reference metric of the minimal spring is hyperbolic, and can be embedded as a minimal surface. We argue that the existence of a continuous set of such isometric minimal surfaces with different extensions leads to a complete degeneracy of the bulk elastic energy of the minimal spring under elongation. This degeneracy is removed only by boundary layer effects. As a result, the mechanical properties of the minimal spring are unusual: the spring is ultrasoft with a rigidity that depends on the thickness t as t7 /2 and does not explicitly depend on the ribbon's width. Moreover, we show that as the ribbon is widened, the rigidity may even decrease. These predictions are confirmed by a numerical study of a constrained spring. This work is the first to address the unusual mechanical properties of constrained non-Euclidean elastic objects.

  4. Non-Mathematics Students' Reasoning in Calculus Tasks

    ERIC Educational Resources Information Center

    Jukic Matic, Ljerka

    2015-01-01

    This paper investigates the reasoning of first year non-mathematics students in non-routine calculus tasks. The students in this study were accustomed to imitative reasoning from their primary and secondary education. In order to move from imitative reasoning toward more creative reasoning, non-routine tasks were implemented as an explicit part of…

  5. Non-locality Sudden Death in Tripartite Systems

    NASA Astrophysics Data System (ADS)

    Jaeger, Gregg; Ann, Kevin

    2009-03-01

    Bell non-locality sudden death is the disappearance of non-local properties in finite times under local phase noise, which decoheres states only in the infinite-time limit. We consider the relationship between decoherence, disentanglement, and Bell non-locality sudden death in bipartite and tripartite systems in specific large classes of state preparation.

  6. Non-perturbative calculation of orbital and spin effects in molecules subject to non-uniform magnetic fields

    NASA Astrophysics Data System (ADS)

    Sen, Sangita; Tellgren, Erik I.

    2018-05-01

    External non-uniform magnetic fields acting on molecules induce non-collinear spin densities and spin-symmetry breaking. This necessitates a general two-component Pauli spinor representation. In this paper, we report the implementation of a general Hartree-Fock method, without any spin constraints, for non-perturbative calculations with finite non-uniform fields. London atomic orbitals are used to ensure faster basis convergence as well as invariance under constant gauge shifts of the magnetic vector potential. The implementation has been applied to investigate the joint orbital and spin response to a field gradient—quantified through the anapole moments—of a set of small molecules. The relative contributions of orbital and spin-Zeeman interaction terms have been studied both theoretically and computationally. Spin effects are stronger and show a general paramagnetic behavior for closed shell molecules while orbital effects can have either direction. Basis set convergence and size effects of anapole susceptibility tensors have been reported. The relation of the mixed anapole susceptibility tensor to chirality is also demonstrated.

  7. Non-linear and non-local behaviour in spontaneously electrical solids.

    PubMed

    Roman, M; Taj, S; Gutowski, M; McCoustra, M R S; Dunn, A C; Keolopile, Z G; Rosu-Finsen, A; Cassidy, A M; Field, D

    2018-02-14

    Using reflection-absorption infrared spectroscopy (RAIRS), we show that solids displaying spontaneous dipole orientation possess quite general non-local and non-linear characteristics, exemplified through their internal electric fields. The most graphic illustration of this, uncovered originally through electron beam studies, may be found in films of cis-methyl formate (cis-MF), for which data demonstrated the counter-intuitive property that the degree of dipole order in the film does not monotonically decrease as the temperature of deposition rises, but rather increases sharply above ∼77 K. Here we show how RAIRS provides independent evidence to support this conclusion. These new data confirm (i) that the behaviour of spontelectrics is governed by an expression for the degree of dipole orientation, which is continuous in temperature, but with a discontinuity in the derivative, and (ii) that the temperature of deposition associated with this discontinuity matches the temperature above which dipole order switches from the expected reduction with temperature to an increase with temperature.

  8. Non-invasive hemoglobin monitoring.

    PubMed

    Joseph, Bellal; Haider, Ansab; Rhee, Peter

    2016-09-01

    Technology has transformed the practice of medicine and surgery in particular over the last several decades. This change in practice has allowed diagnostic and therapeutic tests to be performed less invasively. Hemoglobin monitoring remains one of the most commonly performed diagnostic tests in the United States. Recently, non-invasive hemoglobin monitoring technology has gained popularity. The aim of this article is to review the principles of how this technology works, pros and cons, and the implications of non-invasive hemoglobin technology particularly in trauma surgery. Copyright © 2015 IJS Publishing Group Ltd. Published by Elsevier Ltd. All rights reserved.

  9. A few laced genes: women's standpoint in the feminist ancestry of Dorothy E. Smith.

    PubMed

    Smythe, Deirdre

    2009-04-01

    This article looks at the feminist activism of particular women in the ancestry of the eminent Canadian sociologist, Dorothy E. Smith, and at the archival data that confirm the traces of their influence found in her theory-building. Using the method of interpretative historical sociology and a conceptual framework drawn from Marx called the "productive forces," the article examines the feminist theology of her Quaker ancestor, Margaret Fell, and the militant suffrage activism of her mother and her grandmother, Dorothy Foster Place and Lucy Ellison Abraham, respectively. The article argues that the household labour of the remarkable women in her family line became a "productive force" that facilitated her imagining of the feminist theory, "the standpoint of women".

  10. The issue of race in the work of Domingos Guedes Cabral.

    PubMed

    Arteaga, Juanma Sánchez; Almeida, Ronnie Jorge Tavares de; El-Hani, Charbel Niño

    2016-12-01

    In 1875 Bahia, medicine and evolutionism were used by the physician, journalist, and republican militant Domingos Guedes Cabral as ideological weapons to propose a radical program of social reforms in Brazil in the areas of education, marriage control, medical care to the alienated, changes in the penal system, etc., all of which were based on the scientific knowledge of that time. Among the social ideas of Guedes Cabral, the question of race will be the main focus of this analysis. In this sense, Domingos Guedes Cabral is a particularly significant example for understanding the initial steps in the peculiar alliance between evolutionism, medicine, and scientific racism in Brazil since the 1870s, when Darwinism first arrived in the country.

  11. Security Policy of the Czech Republic in Light of the Integration into the European Union

    DTIC Science & Technology

    2003-03-01

    vývoje států střední a východní Evropy do roku 2015, Military Academy, Brno, 2002, p.11. 29 decisions in strategic security issues. These all combine...politického vývoje států střední a východní Evropy do roku 2015, Military Academy in Brno, 2002, p.22. 77 P.Gerbet, La construction de l´ Europe...vývoje států střední a východní Evropy do roku 2015, ÚSS VA Brno, 2002, p.24. 46 not possible to rationally counter to.97 However, a militant

  12. The ethics of self-sacrifice: what's wrong with suicide bombing?

    PubMed

    Battin, Margaret P

    2004-01-01

    What's wrong with suicide bombing? The tactic has been used by the Tamil Tigers, by the Japanese kamikaze, by al-Qaeda, by Palestinian militants against Israel, by Iraqi defenders loyal to Saddam Hussein against the U.S. invasion, and by others; it is typically understood by these groups as martyrdom rather than suicide. Scientific theories of suicide--biological, psychological, and sociological--do not contribute to an understanding. Nor is the claim that it is amoral, the product of psychopathology or mental illness, adequate. The central moral core of the issue of suicide bombing rests, rather, on the violation of a tacit assumption of equality in combat: "they" have a weapon "we" don't.

  13. Non-equilibrium dynamics from RPMD and CMD.

    PubMed

    Welsch, Ralph; Song, Kai; Shi, Qiang; Althorpe, Stuart C; Miller, Thomas F

    2016-11-28

    We investigate the calculation of approximate non-equilibrium quantum time correlation functions (TCFs) using two popular path-integral-based molecular dynamics methods, ring-polymer molecular dynamics (RPMD) and centroid molecular dynamics (CMD). It is shown that for the cases of a sudden vertical excitation and an initial momentum impulse, both RPMD and CMD yield non-equilibrium TCFs for linear operators that are exact for high temperatures, in the t = 0 limit, and for harmonic potentials; the subset of these conditions that are preserved for non-equilibrium TCFs of non-linear operators is also discussed. Furthermore, it is shown that for these non-equilibrium initial conditions, both methods retain the connection to Matsubara dynamics that has previously been established for equilibrium initial conditions. Comparison of non-equilibrium TCFs from RPMD and CMD to Matsubara dynamics at short times reveals the orders in time to which the methods agree. Specifically, for the position-autocorrelation function associated with sudden vertical excitation, RPMD and CMD agree with Matsubara dynamics up to O(t 4 ) and O(t 1 ), respectively; for the position-autocorrelation function associated with an initial momentum impulse, RPMD and CMD agree with Matsubara dynamics up to O(t 5 ) and O(t 2 ), respectively. Numerical tests using model potentials for a wide range of non-equilibrium initial conditions show that RPMD and CMD yield non-equilibrium TCFs with an accuracy that is comparable to that for equilibrium TCFs. RPMD is also used to investigate excited-state proton transfer in a system-bath model, and it is compared to numerically exact calculations performed using a recently developed version of the Liouville space hierarchical equation of motion approach; again, similar accuracy is observed for non-equilibrium and equilibrium initial conditions.

  14. 34 CFR 74.26 - Non-Federal audits.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Non-Federal audits. 74.26 Section 74.26 Education Office of the Secretary, Department of Education ADMINISTRATION OF GRANTS AND AGREEMENTS WITH INSTITUTIONS OF HIGHER EDUCATION, HOSPITALS, AND OTHER NON-PROFIT ORGANIZATIONS Post-Award Requirements Financial and Program Management § 74.26 Non-Federal...

  15. 22 CFR 145.26 - Non-Federal audits.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Non-Federal audits. 145.26 Section 145.26 Foreign Relations DEPARTMENT OF STATE CIVIL RIGHTS GRANTS AND AGREEMENTS WITH INSTITUTIONS OF HIGHER EDUCATION, HOSPITALS, AND OTHER NON-PROFIT ORGANIZATIONS Post-Award Requirements Financial and Program Management § 145.26 Non-Federal audits. (a)...

  16. 7 CFR 993.108 - Non-human consumption outlet.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ..., that any prunes or prune waste received for a non-human use will be used only within such outlet. [26... 7 Agriculture 8 2012-01-01 2012-01-01 false Non-human consumption outlet. 993.108 Section 993.108... CALIFORNIA Administrative Rules and Regulations Definitions § 993.108 Non-human consumption outlet. Non-human...

  17. 7 CFR 993.108 - Non-human consumption outlet.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ..., that any prunes or prune waste received for a non-human use will be used only within such outlet. [26... 7 Agriculture 8 2014-01-01 2014-01-01 false Non-human consumption outlet. 993.108 Section 993.108... CALIFORNIA Administrative Rules and Regulations Definitions § 993.108 Non-human consumption outlet. Non-human...

  18. Non-food odorants reduce chocolate cravings.

    PubMed

    Kemps, Eva; Tiggemann, Marika; Bettany, Sarah

    2012-06-01

    The present study compared the relative effectiveness of simple, commercially available food and non-food olfactory tasks on chocolate craving reduction. Chocolate cravings were induced by a series of coloured photographs and 67 undergraduate women were asked to smell one of three odours (green apple, jasmine, or water). The non-food odorant (jasmine) significantly reduced chocolate cravings relative to both the food and control odorants. Thus simple non-food odorants offer potential scope as a technique for curbing unwanted food cravings. Copyright © 2012 Elsevier Ltd. All rights reserved.

  19. Open systems & non-formal education

    NASA Astrophysics Data System (ADS)

    Wheeler, Gerald F.

    1988-10-01

    Professor Dib created an important structure that can be used to attach the many and various activities that fall in the category of this title. While I plan to use his structure, I will be emphasizing a different component of his spectrum and promoting a different need. Professor Dib suggested a critical need to move our teaching styles away from formal modes to non-formal modes of delivery. I suggest an equally critical need in the area of informal education. And, I will propose aways to move us toward the same goal, non-formal activities. I believe we need to find ways to use the many informal education activities that occur almost automatically in our societies to move our potential learners to richer non-formal endeavors. Both needs are real; both activities are valid.

  20. Progesterone-Mediated Non-Classical Signaling.

    PubMed

    Garg, Deepika; Ng, Sinnie Sin Man; Baig, K Maravet; Driggers, Paul; Segars, James

    2017-09-01

    Progesterone is essential for pregnancy maintenance and menstrual cycle regulation. Hormone action has been primarily ascribed to the well-characterized classical signaling pathway involving ligand binding, activation of nuclear progesterone receptors (PRs), and subsequent activation of genes containing progesterone response elements (PREs). Recent studies have revealed progesterone actions via non-classical signaling pathways, often mediated by non-genomic signaling. Progesterone signaling, in conjunction with growth factor signaling, impacts on the function of growth factors and regulates important physiological actions such as cell growth and remodeling, as well as apoptosis. This review focuses on non-classical progesterone signaling pathways, both including and excluding PR, and highlights how research in this area will provide a better understanding of progesterone actions and may inform novel therapeutic strategies. Copyright © 2017. Published by Elsevier Ltd.

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