Chemicals involved in honeybee-sunflower relationship.

PubMed

Pham-Delegue, M H; Etievant, P; Guichard, E; Marilleau, R; Douault, P; Chauffaille, J; Masson, C

1990-11-01

We present a review of work on the plant chemicals involved in the honeybee-sunflower model system. Combined behavioral and chemical analyses were conducted under natural and controlled conditions. First the distribution of forager bees' visits on two pairs of sunflower genotypes producing a different level of hybrid seed yield was recorded under pollen-proof tunnels. Mirasol parental lines producing high seed yields were visited at random, whereas forager bees visited preferentially the female parental line of Marianne, resulting in low seed yield. Nectar samples collected on the genotypes were analyzed by gas chromatography. Fructose, glucose, and sucrose were identified. Parental lines of Mirasol showed similar sugar profiles, whereas the female line of Marianne contained higher amounts of sucrose than the male line. We assume that the bees' preferences between genotypes might rely on differences in the sugar composition of floral nectars, especially in the amount of sucrose. Aromas from headspace collection were compared between pairs and periodically during the flowering period. Of the 144 components indexed for Marianne lines and 136 components for Mirasol lines, 17 of the components for Marianne lines and 18 for Mirasol lines differed significantly according to flowering stage. Significant differences appeared in eight of the 134 components of Marianne lines and in 20 of the 250 components for Mirasol lines. Such differences, even restricted to a few components, might account for honeybees' discrimination between genotypes or flowering stage. Experiments then were conducted in a flight room using an artificial flower device. A total volatile extract was used as a conditioning scent previous to the test where the total extract was successively compared to several of its subfractions. Fractions significantly less visited than the total extract were discarded, whereas fractions confused with the total extract were kept. From step to step, a restricted fraction

Trastuzumab Emtansine With or Without Pertuzumab Versus Trastuzumab Plus Taxane for Human Epidermal Growth Factor Receptor 2-Positive, Advanced Breast Cancer: Primary Results From the Phase III MARIANNE Study.

PubMed

Perez, Edith A; Barrios, Carlos; Eiermann, Wolfgang; Toi, Masakazu; Im, Young-Hyuck; Conte, Pierfranco; Martin, Miguel; Pienkowski, Tadeusz; Pivot, Xavier; Burris, Howard; Petersen, Jennifer A; Stanzel, Sven; Strasak, Alexander; Patre, Monika; Ellis, Paul

2017-01-10

Purpose Trastuzumab and pertuzumab are human epidermal growth factor receptor 2 (HER2) -targeted monoclonal antibodies, and trastuzumab emtansine (T-DM1) is an antibody-drug conjugate that combines the properties of trastuzumab with the cytotoxic activity of DM1. T-DM1 demonstrated encouraging efficacy and safety in a phase II study of patients with previously untreated HER2-positive metastatic breast cancer. Combination T-DM1 and pertuzumab showed synergistic activity in cell culture models and had an acceptable safety profile in a phase Ib and II study. Methods In the MARIANNE study, 1,095 patients with centrally assessed, HER2-positive, advanced breast cancer and no prior therapy for advanced disease were randomly assigned 1:1:1 to control (trastuzumab plus taxane), T-DM1 plus placebo, hereafter T-DM1, or T-DM1 plus pertuzumab at standard doses. Primary end point was progression-free survival (PFS), as assessed by independent review. Results T-DM1 and T-DM1 plus pertuzumab showed noninferior PFS compared with trastuzumab plus taxane (median PFS: 13.7 months with trastuzumab plus taxane, 14.1 months with T-DM1, and 15.2 months with T-DM1 plus pertuzumab). Neither experimental arm showed PFS superiority to trastuzumab plus taxane. Response rate was 67.9% in patients who were treated with trastuzumab plus taxane, 59.7% with T-DM1, and 64.2% with T-DM1 plus pertuzumab; median response duration was 12.5 months, 20.7 months, and 21.2 months, respectively. The incidence of grade ≥ 3 adverse events was numerically higher in the control arm (54.1%) versus the T-DM1 arm (45.4%) and T-DM1 plus pertuzumab arm (46.2%). Numerically fewer patients discontinued treatment because of adverse events in the T-DM1 arms, and health-related quality of life was maintained for longer in the T-DM1 arms. Conclusion T-DM1 showed noninferior, but not superior, efficacy and better tolerability than did taxane plus trastuzumab for first-line treatment of HER2-positive, advanced breast

Karin Sinclair | NREL

Science.gov Websites

effort under the Distributed Wind research portfolio focused on supporting the distributed wind sector to reduce the levelized cost of energy and increase the number of certified turbines for distributed

Trastuzumab Emtansine With or Without Pertuzumab Versus Trastuzumab Plus Taxane for Human Epidermal Growth Factor Receptor 2–Positive, Advanced Breast Cancer: Primary Results From the Phase III MARIANNE Study

PubMed Central

Perez, Edith A.; Barrios, Carlos; Eiermann, Wolfgang; Toi, Masakazu; Im, Young-Hyuck; Conte, Pierfranco; Martin, Miguel; Pienkowski, Tadeusz; Pivot, Xavier; Burris, Howard; Petersen, Jennifer A.; Stanzel, Sven; Strasak, Alexander; Patre, Monika; Ellis, Paul

2017-01-01

Purpose Trastuzumab and pertuzumab are human epidermal growth factor receptor 2 (HER2) –targeted monoclonal antibodies, and trastuzumab emtansine (T-DM1) is an antibody–drug conjugate that combines the properties of trastuzumab with the cytotoxic activity of DM1. T-DM1 demonstrated encouraging efficacy and safety in a phase II study of patients with previously untreated HER2-positive metastatic breast cancer. Combination T-DM1 and pertuzumab showed synergistic activity in cell culture models and had an acceptable safety profile in a phase Ib and II study. Methods In the MARIANNE study, 1,095 patients with centrally assessed, HER2-positive, advanced breast cancer and no prior therapy for advanced disease were randomly assigned 1:1:1 to control (trastuzumab plus taxane), T-DM1 plus placebo, hereafter T-DM1, or T-DM1 plus pertuzumab at standard doses. Primary end point was progression-free survival (PFS), as assessed by independent review. Results T-DM1 and T-DM1 plus pertuzumab showed noninferior PFS compared with trastuzumab plus taxane (median PFS: 13.7 months with trastuzumab plus taxane, 14.1 months with T-DM1, and 15.2 months with T-DM1 plus pertuzumab). Neither experimental arm showed PFS superiority to trastuzumab plus taxane. Response rate was 67.9% in patients who were treated with trastuzumab plus taxane, 59.7% with T-DM1, and 64.2% with T-DM1 plus pertuzumab; median response duration was 12.5 months, 20.7 months, and 21.2 months, respectively. The incidence of grade ≥ 3 adverse events was numerically higher in the control arm (54.1%) versus the T-DM1 arm (45.4%) and T-DM1 plus pertuzumab arm (46.2%). Numerically fewer patients discontinued treatment because of adverse events in the T-DM1 arms, and health-related quality of life was maintained for longer in the T-DM1 arms. Conclusion T-DM1 showed noninferior, but not superior, efficacy and better tolerability than did taxane plus trastuzumab for first-line treatment of HER2-positive, advanced breast

75 FR 76482 - Federal Housing Administration (FHA): FHA Maximum Loan Limits for 2011

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-08

... http://www.hud.gov/offices/adm/hudclips/letters/mortgagee/ . FOR FURTHER INFORMATION CONTACT: Karin B... be found at http://www.hud.gov/offices/adm/hudclips/letters/mortgagee/ mortgagee/. Dated: November 29...

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rodland, Karin

New research identifies critical proteins present in the tumors of women with ovarian cancer. Karin Rodland discusses the work led by PNNL and Johns Hopkins researchers, working with collaborators across the nation.

The Inner Workings of Ovarian Cancer

ScienceCinema

Rodland, Karin

2018-06-12

New research identifies critical proteins present in the tumors of women with ovarian cancer. Karin Rodland discusses the work led by PNNL and Johns Hopkins researchers, working with collaborators across the nation.

(Ig)Noble Lies: Personal Historicism and Richard Mulcaster's "Positions Concerning the Bringing up of Children" (1581)

ERIC Educational Resources Information Center

De Barros, Eric

2013-01-01

Attempting to push early modern presentism to the radical, logical conclusion of a more personal historicism, this essay draws on a number of interpretive practices and theoretical insights--Stephen Greenblatt's self-reflectivity, Toni Morrison's "rememory," Marianne Hirsch's "postmemory," bell hooks's "passion of…

Getting Ready for a Nuclear-Ready Iran

DTIC Science & Technology

2005-10-01

College’s Strategic Studies Institute. The Nonproliferation Policy Education Center (NPEC) has worked closely with Dr. Douglas Lovelace , Ms. Marianne...essays and of NPEC’s Deputy Executive Director, Amanda Sokolski, my wife; and our assistant, Mohammad Nasseri-Asl, in pulling it all together. Without

IFLA General Conference, 1989. Division of Education and Research. Section on Education and Training; Round Table on Library History; Round Table on Research in Reading; Round Table on Continuing Professional Education. Booklet 70.

ERIC Educational Resources Information Center

International Federation of Library Associations, The Hague (Netherlands).

There are 10 papers in this collection from the Division of Education and Research: (1) "The Importance of Basic Training in Marketing for Librarians and Information Professionals" (French and English versions; Rejean Savard); (2) "Information Management Education: Some Interdisciplinary Approaches" (Marianne Broadbent); (3) "Educational…

Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (78th, Washington, DC, August 9-12, 1995). Science Communications Interest Group.

ERIC Educational Resources Information Center

Association for Education in Journalism and Mass Communication.

The Science Communication Interest Group section of the proceedings contains the following seven papers: "Using Television to Foster Children's Interest in Science" (Marie-Louise Mares and others); "Trends in Newspaper Coverage of Science over Three Decades: A Content Analytic Study" (Marianne G. Pellechia); "Media…

Adoptive T cell cancer therapy

NASA Astrophysics Data System (ADS)

Dzhandzhugazyan, Karine N.; Guldberg, Per; Kirkin, Alexei F.

2018-06-01

Tumour heterogeneity and off-target toxicity are current challenges of cancer immunotherapy. Karine Dzhandzhugazyan, Per Guldberg and Alexei Kirkin discuss how epigenetic induction of tumour antigens in antigen-presenting cells may form the basis for multi-target therapies.

Trends and Issues in Elementary Language Arts. Trends and Issues in English Language Arts, 1999.

ERIC Educational Resources Information Center

National Council of Teachers of English, Urbana, IL.

This publication contains journal essays and book chapters from publications of the National Council of Teachers of English. The following articles appear in the publication's first section, "Multimedia in the Classroom": (1) "The Classroom" (Marilyn Jody and Marianne Saccardi); (2) "Let's Go to the Movies: Rethinking the…

New Media. [SITE 2001 Section].

ERIC Educational Resources Information Center

McNeil, Sara, Ed.

This document contains the following papers on new media from the SITE (Society for Information Technology & Teacher Education) 2001 conference: "Interactive Multimedia Problem-Based Learning: Evaluating Its Use in Pre-Service Teacher Education" (Peter Albion); "Digital Audio Production for the Web" (Jeffrey W. Bauer and Marianne T. Bauer);…

78 FR 24226 - Notice of Proposed Information Collection: Comment Request; FHA TOTAL (Technology Open to...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-24

... Information Collection: Comment Request; FHA TOTAL (Technology Open to Approved Lenders) Mortgage Scorecard... proposed information collection requirement described below will be submitted to the Office of Management... Information Service (1-800-877-8339). FOR FURTHER INFORMATION CONTACT: Karin B. Hill, Director, Office of...

77 FR 65361 - Xanthan Gum From Austria and the People's Republic of China: Postponement of Preliminary...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-26

... Austria and the People's Republic of China: Postponement of Preliminary Determinations of Antidumping Duty...: October 26, 2012. FOR FURTHER INFORMATION CONTACT: Karine Gziryan (Austria) or Brandon Farlander (People's... of initiation of antidumping duty investigations of xanthan gum from Austria and the People's...

Why You'll Never Catch Smallpox

ERIC Educational Resources Information Center

Cutler, Marianne; Lawrence, Liz

2016-01-01

In this article, Marianne Cutler and Liz Lawrence describe in more detail the opportunities for "working scientifically" provided by this new Association for Science Education (ASE) resource, which was introduced in the previous issue, along with some of the feedback from teachers who have trialled the resources. [This article was…

A Yearning for Wholeness: Spirituality in Educational Philosophy

ERIC Educational Resources Information Center

Hurley, Angela

2012-01-01

Numerous popular figures currently espouse the importance of spirituality. Some prominent voices, such as Deepak Chopra, Marianne Williamson, and Eckhart Tolle, advocate a more spiritual existence, warning that the earth and humanity are engaged in a seismic change. The shift of spiritual leaders from fringe to fairly mainline attention is…

A Portable Burn Pan for the Disposal of Excess Propellants

DTIC Science & Technology

2015-11-01

National Guard Bureau; John Hunt , formerly at Camp Grayling; Jo Anderson, formerly at Ft. Indiantown Gap; and Steve Thurmond, formerly at US Army Alaska...Finally at CRREL, Marianne Walsh, Charlie Smith, Tommie Hall, Matt Bigl, Chris Donnelly, and Jordan Hodge all played major roles in the success of the burn pan.

Deaf-Blind Perspectives, 1998-1999.

ERIC Educational Resources Information Center

Malloy, Peggy, Ed.

1998-01-01

This collection of three issues focuses on competencies for teachers of learners who are deaf-blind, living with deaf-blindness, and resources in Australia for parents and families of students who are deaf-blind. Articles include: (1) "Research-to-Practice Focus: Competencies for Teachers of Learners Who Are Deafblind" (Marianne Riggio),…

Poets Teaching Poets: Self and the World.

ERIC Educational Resources Information Center

Orr, Gregory, Ed.; Voigt, Ellen Bryant, Ed.

This anthology collects essays by current and former lecturers at the Warren Wilson College (North Carolina) MFA Program for Writers. Some of the poets whose essays are included are: Joan Aleshire, Marianne Boruch, Carl Dennis, Stephen Dobyns, Reginald Gibbons, Louise Gluck, Allen Grossman, Robert Hass, Tony Hoagland, Heather McHugh, Gregory Orr,…

Is "Gender-Sensitive Education" a Useful Concept for Educational Policy?

ERIC Educational Resources Information Center

Forde, Christine

2014-01-01

This article responds to Astrid Sinnes and Marianne Løken's article "Gendered education in a gendered world: Looking beyond cosmetic solutions to the gender gap in science" by exploring the idea of "gender-sensitive" education and its usefulness in educational policy. It draws on theoretical discussions of the concept of…

Schools That Succeed: How Educators Marshal the Power of Systems for Improvement

ERIC Educational Resources Information Center

Chenoweth, Karin

2017-01-01

Informed by years of research and on-the-ground reporting, "Schools That Succeed" is Karin Chenoweth's most inspiring and compelling book yet--an essential read for educators who seek to break the stubborn connection between academic achievement and socioeconomic status. Chenoweth draws on her decade-long journey into neighborhood…

The End of the Six-Party Talks?

DTIC Science & Technology

2007-01-01

Pyongyang is wary of Beijing’s international influence, its ability to collaborate with the United States and South Korea, its willingness to foster ...Kenneth Quinones, “ Dualism in the Bush Administration’s North Korea Policy,” Asian Perspective, XXVII, no. 1, 2003, 197-224; Karin Lee and Adam Miles

Adaptive Rules In Emergent Logistics (ARIEL) An Agent-Based Analysis Environment to Study Adaptive Route-Finding Constantly Changing Road-Networks

DTIC Science & Technology

2003-06-01

my wife Karin, my daughter Jasmin and my son Jan for their support and huge patience. Without the security and support of a loving home, none of...contains the trucks, which are the only moveable objects in the system. In essence they provide functionality and cannot act themselves. The layer

Persistent Discourses in Physics Education: Gender Neutrality and the Gendering of Competence

ERIC Educational Resources Information Center

Gonsalves, Allison

2014-01-01

In her article, Karin Due presents us with a contradiction in physics: the construction of physics as a symbolically masculine discipline alongside a simultaneous discourse of the "gender-neutrality" of the discipline. Due's article makes an important contribution to the study of the gendering of physics practices, particularly in…

The Limits of Soviet Airpower: The Bear Versus the Mujahideen in Afghanistan, 1979-1989

DTIC Science & Technology

1997-06-01

satellite imagery identified Soviet TMS-65 decontamination vehicles and AGV-3 detox chambers in the vicinity of combat areas. In addition, the...Vladislav Tamarov, Afghanistan: Soviet Vietnam, trans. Naomi Marcus, Marianne Clarke Trangen, and Vladislav Tamarov (San Francisco: Mercury House...Tamarov. San Francisco: Mercury House, 1992. Turbiville, Graham. Ambush! The Road War in Afghanistan. Fort Leavenworth, KS: Soviet Army Studies Office

Constitutive Activation of NF-kappaB in Prostate Carcinoma Cells Through a Positive Feedback Loop: Implication of Inducible IKK-Related Kinase (IKKi)

DTIC Science & Technology

2004-08-01

development in different tissues is strongly considered ( Greten and Karen, 2004). To assess the effect of w.t. IKKi and kinase inactive IKKi mutant...11: 1357-1362, 1999. 3. Greten FR, Karin M. The IKK/NF-kappaB activation pathway-a target for prevention and treatment of cancer. Cancer Lett. 206(2

Astronaut C. Michael Foale is briefed on use of Sky Genie

NASA Technical Reports Server (NTRS)

1994-01-01

Astronaut C. Michael Foale, STS-63 mission specialist, is briefed on the use of Sky Genie device by Karin L. Porter. The device would aid in emergency egress operations aboard a troubled Space Shuttle. Porter, an employee of Rockwell International, helps train astronauts in egress procedures at JSC's Shuttle mockup and integration laboratory.

77 FR 36285 - Notice of Proposed Information Collection: Comment Request; Application for Fee or Roster...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-18

... the FHA insurance fund. Agency form numbers, if applicable: HUD-92563I, HUD 92563A, HUD 92564-CN... to the proposal by name and/or OMB Control Number and should be sent to: Reports Liaison Officer... number for the Federal Information Relay Service (1-800-877-8339). FOR FURTHER INFORMATION CONTACT: Karin...

Getting It Done: Leading Academic Success in Unexpected Schools

ERIC Educational Resources Information Center

Chenoweth, Karin; Theokas, Christina

2011-01-01

"Getting It Done" describes in clear and helpful detail what leaders of successful high-poverty and high-minority schools have done to promote and sustain student achievement. It follows two celebrated books by Karin Chenoweth: "It's Being Done," which established that the work of educating all children is possible, and "How It's Being Done,"…

Role of ets Oncogenes in the Progression of Breast Cancer

DTIC Science & Technology

1998-10-01

8217 References 167 Arias J, Alberts AS, Brindle P, Claret FX, Smeal T, Karin M, May WA, Lessnick SL, Braun BS, Klemsz M, Lewis BC, Feramisco J and Montminy M...0 and Shaw PE. (1994). Mol. Cell. Oncogene, 8, 3459-3464. Biol., 14, 4815-4824. Bories J, Willerford DM, Grevin D, Davidson L, Camus A, Lopez M

Is `gender-sensitive education' a useful concept for educational policy?

NASA Astrophysics Data System (ADS)

Forde, Christine

2014-06-01

This article responds to Astrid Sinnes and Marianne Løken's article `Gendered education in a gendered world: Looking beyond cosmetic solutions to the gender gap in science' by exploring the idea of `gender-sensitive' education and its usefulness in educational policy. It draws on theoretical discussions of the concept of gender and of difference to consider ways in which `gender-sensitive' education might serve the task of promoting equality and justice.

Alternative World Scenarios for Strategic Planning

DTIC Science & Technology

1988-01-20

STRATEGIC STUDIES INSTITUTE U.S. ARMY WAR COLLEGE CARLISLE BARRACKS, PENNSYLVANIA 17013-5050 20 JANUARY 198 ACN 81001 Lfl 0ALTERNATIVE WORLD...Howard D. Graves STRATEGIC STUDIES INSTITUTE Director Colonel Thomas R. Stone Author Charles W. Tayloi Editor Marianne P. Cowling Secretary Shirley A...Shearer STRATEGIC STUDIES INSTITUTE U.S. ARMY WAR COLLEGE Carlisle Barracks, Pennsylvania 17013-5050 20 January 1988 ACN 88001 4e 4’ ALTERNATIVE

Proceedings of the Annual Army Environmental R and D Symposium (15th) Held in Williamsburg, Virginia on 25-27 June 1991

DTIC Science & Technology

1991-06-01

Composting for the Bioremediation of Explosives-Contaminated Soils ... 285 Richard T Williams , CPT Kevin R. Keehan, Wayne Sisk, and MAJ Craig A. Myler...Ford, William A. Tucker, Carolyn L. Fordham, and Roberta L. Ober TNT Metabolites in Animal Tissues From U3 Army Ammunition Site ............... 551 L.R...Anchorage, Alaska ............. 563 Charles H. Racine, Marianne E. WaLt4 Charles M. Collins, Bill D. Roebuck, and William Gossweiler GROUNDWATER AND

Perspectives on Positioning, Interaction, and Learning in Small-Group Discussion: Possibilities for Extending the Analytic Lens

ERIC Educational Resources Information Center

Kittleson, Julie M.; Wilson, Rachel E.

2014-01-01

In this forum piece, we respond to Karin Due's study of social dynamics in groups of students in physics class and gender issues that play out in this context. We discuss two threads that appear in Due's paper: one pertains to patterns of talk within groups and how these patterns open up possibilities for learning, the other pertains to…

List of Publications 1980-1981

DTIC Science & Technology

1981-01-01

GROUP SIZE 346 DE ALENCAR F, BORGSTROM M, QUINTANA L , PSIQUIATRIA SOCIAL , PSICOLOGIA Y SALUD MENTAL EN AMERICA LATINA, UNA REVISION BIBLIOGRAFICA CON...Health Training Centre on Psycho- social Factors and Health LIST OF PUBLICATIONS 19-80-1981 ’ ,JAN 4 1982 Th7 dcument has been approvedfox public release...chapter has been prepared on "Work Stress Related to Social Struc- tures and Processes", in collaboration with Drs. Marianne Franken- haeuser and Bertil

Review of National Work Programme on the Long Term Effects of Sustained High G on the Cervical Spine (Analyse du programme de travail national : les effets long terme sur la colonne cervicale d’un nombre de G lev et prolong )

DTIC Science & Technology

2008-12-01

Prof. Karin Harms-Ringdahl, PhD, RPT Karolinska Institutet Department of Neurobiology, Care Sciences, and Society Division of Physiotherapy 23100...Äng Karolinska Institutet Department of Neurobiology, Care Sciences, and Society Division of Physiotherapy Alfred Nobels Allé 23100 SE-14183...report is in preparation. The RAF has an ongoing project (from August 2006 to September 2007) determining the need for physiotherapy for aircrew on the

JPRS Report, West Europe.

DTIC Science & Technology

1987-08-11

11 AUGUST 1987 WEST EUROPE CONTENTS POLITICAL FEDERAL REPUBLIC OF GERMANY Greens Divided Over Defense Policy (SUEDDEUTSCHE ZEITUNG, 20, 21 Jun...Depopulation (Karin Henriksson, Emily von Sydow; SVENSKA DAGBLADET, 30 May 87) H /9986 - d - FEDERAL REPUBLIC OF GERMANY POLITICAL GREENS DIVIDED ...React Much More Vigorously to Threats to Freedom In this connection, I want to draw the attention of the National Conference to the seriousness and

T-38 A- AIRCRAFT (NASA 924)

NASA Image and Video Library

1983-12-07

S82-33032 (30 June 1982) --- This scene shows activity at the spacecraft communicator and flight activities officer consoles in the mission operations control room (MOCR) in the Johnson Space Center?s mission control center (MCC). Astronaut Brewster H. Shaw Jr., right, Astronaut Roy D. Bridges Jr. and Marianne J. Dyson are pictured during STS-4?s Day 4 activity. Shaw and Bridges are spacecraft communicators and Dyson is a flight activities officer on the entry team.

Identifying and Leveraging Trust as a Key Element in the Development, Implementation and Sustainment of the Salt Lake City Fire Department’s Intelligence Program

DTIC Science & Technology

2014-09-01

this amazing adventure. An education in self-exploration balanced with relentless tests of my stamina and mettle. To my classmates: Thank you for...Karin and son Scott, thank you for providing the comic relief so needed throughout this process. And most importantly, to my husband, Jeff: There...development of a fire intelligence program.190191 In her NPS Masters Thesis, Terrorism Awareness and Education as a Prevention Strategy for First

Training Aide: Research and Guidance for Effective Training User Guide

DTIC Science & Technology

2013-12-01

Research Product 2014-02 Training Aide: Research and Guidance for Effective Training User Guide Beth Plott Shaun...Effective Training User Guide 5a. CONTRACT OR GRANT NUMBER W91WAW-07-C-0081 5b. PROGRAM ELEMENT NUMBER 611102 6. AUTHOR(S) Beth Plott...Representative and Subject Matter POC: Karin A. Orvis 14. ABSTRACT: This is a user guide for the web-based tool called Training Aide: Research and Guidance

To Investigate the Therapeutic Efforts of the COX-2 Inhibitor NS-398 as a Single Agent, and in Combination with Vitamin D, in Vitro and in Vivo

DTIC Science & Technology

2008-01-01

by immunoelectron microscopy. The Journal Of Biological Chemistry 1998;273:9886-93. 29. Iniguez M, Rodriguez A, Volpert O, Fresno M, Redondo J...controlled by local hypoxia that induces the synthesis of angio- genic factors that can activate signal pathways and transcrip- tion for endothelial...Helmberg,A. and Karin,M. (1995) Immunosuppression by glucocorticoids: inhibition of NF-kappa B activity through induction of I kappa B synthesis . Science

CPTAC Investigators Discuss Research Insights and Perspectives as part of ASBMB Journal Club - 12 Nov | Office of Cancer Clinical Proteomics Research

Cancer.gov

On Wednesday, November 12, 2014 from 2:00 PM to 3:00 PM EST, Daniel Liebler, PhD (Vanderbilt University) and Karin Rodland, PhD (Pacific Northwestern National Laboratory) and Ruedi Aebersold, PhD (Swiss Federal Institute of Technology) will share their research insight as part of the ASBMB Journal Club.  Both Doctors Liebler and Rodland are Principal Investigators in the NCI’s Clinical Proteomic Tumor Analysis Consortium.

Ergonomic evaluation of workload by milk production - a bibliometric analysis.

PubMed

de Oliveira, Claudilaine Caldas; Pereira Moro, Antônio Renato; Ulbricht, Leandra; Belinelli, Marjorie; de Souza, Gilberto F M; Gabriel, Michele; Zattar, Izabel Cristina

2017-09-21

The purpose of this study was to select in a structured manner the relevant articles with scientific recognition, and simultaneously identify the characteristics of these publications that may scientifically enrich the theme in a portfolio of papers. The theme involves ergonomics in milk production as a criterion for evaluating and improving organizational performance in the milking sector. The study used ProKnow-C as a theoretical instrument for intervention. The main results show: i) a bibliographic portfolio of 18 items aligned with the view adopted by researchers which served as a theoretical framework for this research; ii) The article entitled "Wrist positions and movements as possible risk factors during machine milking", by Marianne Stål, Gert-Åke Hansson and Ulrich Moritz in 1999 and published in the Journal of Applied Ergonomics presented the highest scientific recognition, iii) the authors highlighted in the bibliographic portfolio or in its references researching the subject are Gert-Åke Hansson, Marianne Stål and Stefan Pinzke, and iv) the International Journal of Industrial Ergonomics shows the highest number of scientific articles in the bibliographic portfolio. The studies selected using the methodology indicate research in ergonomics focused on the production of milk in rural areas, specifically in the milking sector, are generally related to the health and safety of the workers.

An Overview of Acoustic Detection Analysis.

DTIC Science & Technology

1983-01-01

PL(r) and NL are typically determined from publica - tions that give geographic and seasonal values for these parameters. The left-hand side of the...In Seguridad hence) 14 p., Oct 1980, AD A092 733 wiorthwstern University, Evanston, IL PP 297 - Classified PP 3o9 Bowes, Marianne, Brchling, Frank P...Siultaneous PP 36 Determination of Income and Employment in United States-- U’NeIll, Thomas, Řool ltv riels for the Na.y," I oc., Mexico Border

Scanning the Horizon: Implications for Navy Strategy of National, Joint and Other Services’ Strategic Trends

DTIC Science & Technology

2012-02-01

CJCS’s) companion document, the Capstone Concept for Joint Operations (CCJO) (discussed below) "ibid., 28. "That said, it should be noted that it...Capstone Concept for Joint Operations (CCJO) The companion document to the JOE that answers the challenges of the future identified in the JOE (and...Karin E. Kitchens , Aaron Martin, A Review of the Army’s Modular Force Structure" (RAND National Defense Research Institute, Technical Report,Jun. 2011

Statements of IRAQI Communist Leaders.

DTIC Science & Technology

1960-07-19

Leader Abdul Karin Kassem J,.’l ; The Maintenance and Consolidation of Party Idfe Is a Deeply Sincere Policy of Cur Democratic Government STATEMENTS...OF IRAQI COMMUNIST LEADERS 1» Open Letter to His Excellency the Leader Abdul .Karflm Kassem /following is a ^translation of an article by the...they also exercised political influence and thus the fate of the feudalists was linked to the continued exploitation of our wealth, our natural

Equitable PERSTEMPO - The Challenge for Long-Term Deployed Armed Forces

DTIC Science & Technology

2003-04-07

substantial impact on the operational effectiveness of the Bundeswehr of the future.  Rudolf Scharping Former Federal Minister of Defense The vision...Federal Minister of Defense, Rudolf Scharping, initiated a new force planning by means of the so-called "Cornerstones Paper" on 01 June 2000, the Chief of...Annex 1) 77 Rainer Marr, Timea Biro, and Karin Steiner , Vereinbarkeit von Familie und Beruf des Soldaten – Moeglichkeiten und Grenzen einer

A Comparison of the Compression Response of Thick (6.35mm) and Thin (1.60mm) Dry and Moisture Saturated AS4/3501-6 Laminates

DTIC Science & Technology

1990-10-01

of 1.27 mm/mm/min (0.05 in./in./min.) using a 60 kip Satec universal machine, with a spherically seated compression platen for alignment purposes. At...Task No. 6. AUTHOR(S) R3450SOS, ROOONOO, Work Karin Gipple Unit No. 2802-950 and 2844-220 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS( ES ) 8... ES ) 10. SPONSORING /MONITOR ING AGENCY REPORT NUMBER DTRC Materials Block, IR 11. SUPPLEMENTARY NOTES 12a. DISTRIBUTION /AVAILABILTY STATEMENT 12b

Chemotherapeutic Targeting of Fibulin-5 to Suppress Breast Cancer Invasion and Metastasis Stimulated by Transforming Growth Factor-Beta

DTIC Science & Technology

2012-10-22

Res. Commun 2004;316:997–1001. [PubMed: 15044083] 178. Karin M. NF-κB in cancer development and progression. Nature 2006;441:431. [PubMed: 16724054...of TWIST gene expression. Cancer Res 2007;67:9066–9076. [PubMed: 17909010] 199. Ali S, Coombes RC. Endocrine-responsive breast cancer and strategies...for combating resistance. Nat. Rev. Cancer 2002;2:101–112. [PubMed: 12635173] 200. Coombes RC, Gibson L, Hall E, Emson M, Bliss J. Aromatase

Implications of Integrating Women into the Marine Corps Infantry

DTIC Science & Technology

2015-01-01

account by the research. 17 Guy L. Siebold, “The Essence of Military Group Cohesion,” Armed Forces and Society, Vol. 33, No. 2, January 1, 2007, pp...assignment of female personnel reveals a dearth of critical mass concepts: 24 Jasmin Joecks, Kerstin Pull, and Karin Vetter, “Gender Diversity in the...Personnel Psychology, Vol. 60, No. 2, 2007, pp. 303–335. 42 David M. Marx and Jasmin S. Roman, “Female Role Models: Protecting Women’s Math Test

Prevention of Breast Cell Transformation by Blockade of the AP-1 Transcription Factor.

DTIC Science & Technology

1997-09-01

Alto, CA) to normal for transfection efficiency. Both the CAT (from Dr. M . Karin) and Luciferase reporter plasmids used were: -73/+63 ColCAT, -73/+63...1. Table 1: HMECs used in this study. Cells Name Source Phenotype Normal HMECs: NHMEC Clonetics Senescent, anchorage-dependent 184 M . Stampfer...Immortal HMECs: 184A I N5 M . Stampfer Immortal, anchorage dependent 184B5 M . Stampfer MCF10A A. Russo Transformed HMECs: MCF1OAneoT (ras) A. Russo Immortal

Regulation of Estrogen Receptor Transcription in Breast Carcinoma.

DTIC Science & Technology

1998-10-01

E-cadherin 40 and HSP27 41. It is certainly plausible to hypothesize a role for ERF-1 in the coordinate regulation of a set of genes in hormonally...responsive carcinomas. This conjecture is supported by the fact that breast carcinoma cell lines that express E-cadherin and HSP27 are also ERF- 1...regulatory promoter elements of the hsp27 gene in human breast cancer cells. Biochem. Biophys. Res. Com. 222, 155-163 (1996). 42. Imagawa, M., Chiu, R. & Karin

A Case Study in Security Sector Reform: Learning from Security Sector Reform/Building in Afghanistan (October 2002-September 2003)

DTIC Science & Technology

2009-11-01

Amb G (Ambassador-Italy)10. Mrs. G (ISAF Political Advisor)11. Amb K (Amb-Japan)12. Mr. K (ISAF PolAd)13. Mrs. M (Chargé-Netherlands)14. Mr. M ...DCM-Japan)15. BG M (Senior Military Advisor-Finland)16. Amb N (Amb-UK)17. Mr. S (DCM-Germany)18. Lt Col S (MilAd-GE)19. Amb T (Donor Asst-U.S...Building, Year One: From Bonn to Kabul.” Antonio Donini , Norah Niland, and Karin Wermester, eds., Nation Building Unraveled, pp. 39-60. Bloomfield, CT

The U.S. Navy in the World (1991-2000): Context for U.S. Navy Capstone Strategies and Concepts

DTIC Science & Technology

2012-03-01

D0026420.A2/Final March 2012 CNA ANALYSIS & SOLUTIONS CNA is a not-for-profit organization whose professional staff of over 700 provides in-depth...www.dtic.mil or contact CNA Document Control and Distribution Section at 703-824-2123. Copyright © 2012 CNA This work was created in the performance of...N00014-11-D-0323 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER N/A 6. AUTHOR(S) Swartz, Peter M. Duggan, Karin 5d. PROJECT NUMBER N/A 5e. TASK

Initial velocity V-shapes of young asteroid families

NASA Astrophysics Data System (ADS)

Bolin, Bryce T.; Walsh, Kevin J.; Morbidelli, Alessandro; Delbó, Marco

2018-01-01

Ejection velocity fields of asteroid families are largely unconstrained due to the fact that members disperse relatively quickly on Myr time-scales by secular resonances and the Yarkovsky effect. The spreading of fragments in a by the Yarkovsky effect is indistinguishable from the spreading caused by the initial ejection of fragments. By examining families <20 Myr old, we can use the V-shape identification technique to separate family shapes that are due to the initial ejection velocity field and those that are due to the Yarkovsky effect. Asteroid families that are <20 Myr old provide an opportunity to study the velocity field of family fragments before they become too dispersed. Only the Karin family's initial velocity field has been determined and scales inversely with diameter, D-1. We have applied the V-shape identification technique to constrain young families' initial ejection velocity fields by measuring the curvature of their fragments' V-shape correlation in semimajor axis, a, versus D-1 space. Curvature from a straight line implies a deviation from a scaling of D-1. We measure the V-shape curvature of 11 young asteroid families including the 1993 FY12, Aeolia, Brangane, Brasilia, Clarissa, Iannini, Karin, Konig, Koronis(2), Theobalda and Veritas asteroid families. We find that the majority of asteroid families have initial ejection velocity fields consistent with ∼D-1 supporting laboratory impact experiments and computer simulations of disrupting asteroid parent bodies.

In Brief: U.S. Volcano Early Warning System; Bill provides clear mandate for NOAA

NASA Astrophysics Data System (ADS)

Showstack, Randy

2005-05-01

The U.S. Geological Survey on 29 April released a comprehensive review of the 169 U.S. volcanoes, and established a framework for a National Volcano Early Warning System that is being formulated by the Consortium of U.S. Volcano Observatories. The framework proposes an around-the-clock Volcano Watch Office and improved instrumentation and monitoring at targeted volcanoes. The report, authored by USGS scientists John Ewert, Marianne Guffanti, and Thomas Murray, notes that although a few U.S. volcanoes are well-monitored, half of the most threatening volcanoes are monitored at a basic level and some hazardous volcanoes have no ground-based monitoring.

An Assessment of Spaceborne Near-Nadir Interferometric SAR Performance Over Inland Waters with Real

NASA Astrophysics Data System (ADS)

Tan, H.; Li, S. Y.; Liu, Z. W.

2018-04-01

Elevation measurements of the continental water surface have been poorly collected with in situ measurements or occasionally with conventional altimeters with low accuracy. Techniques using InSAR at near-nadir angles to measure the inland water elevation with large swath and with high accuracy have been proposed, for instance, the WSOA on Jason 2 and the KaRIn on SWOT. However, the WSOA was abandoned unfortunately and the SWOT is planned to be launched in 2021. In this paper, we show real acquisitions of the first spaceborne InSAR of such kind, the Interferometric Imaging Radar Altimeter (InIRA), which has been working on Tiangong II spacecraft since 2016. We used the 90-m SRTM DEM as a reference to estimate the phase offset, and then an empirical calibration model was used to correct the baseline errors.

Persistent discourses in physics education: gender neutrality and the gendering of competence

NASA Astrophysics Data System (ADS)

Gonsalves, Allison

2014-06-01

In her article, Karin Due presents us with a contradiction in physics: the construction of physics as a symbolically masculine discipline alongside a simultaneous discourse of the "gender-neutrality" of the discipline. Due's article makes an important contribution to the study of the gendering of physics practices, particularly in group dynamics, and how this serves to simultaneously reinforce the two competing discourses of physics as a masculine discipline, and the discourse of physics as a gender neutral discipline. Due also suggests that an implication of this contradiction is a limited number of available positions for girls in physics compared to those available to boys. I wish to take up this observation and discuss how available positions for boys and girls in physics are related quite closely to two other concepts discussed in Due's article: competence and recognition.

ERAST: Scientific Applications and Technology Commercialization

NASA Technical Reports Server (NTRS)

Hunley, John D. (Compiler); Kellogg, Yvonne (Compiler)

2000-01-01

This is a conference publication for an event designed to inform potential contractors and appropriate personnel in various scientific disciplines that the ERAST (Environmental Research Aircraft and Sensor Technology) vehicles have reached a certain level of maturity and are available to perform a variety of missions ranging from data gathering to telecommunications. There are multiple applications of the technology and a great many potential commercial and governmental markets. As high altitude platforms, the ERAST vehicles can gather data at higher resolution than satellites and can do so continuously, whereas satellites pass over a particular area only once each orbit. Formal addresses are given by Rich Christiansen, (Director of Programs, NASA Aerospace Technology Ent.), Larry Roeder, (Senior Policy Advisor, U.S. Dept. of State), and Dr. Marianne McCarthy, (DFRC Education Dept.). The Commercialization Workshop is chaired by Dale Tietz (President, New Vista International) and the Science Workshop is chaired by Steve Wegener, (Deputy Manager of NASA ERAST, NASA Ames Research Center.

New insights on the Karoo shale gas potential from borehole KZF-1 (Western Cape, South Africa)

NASA Astrophysics Data System (ADS)

Campbell, Stuart A.; Götz, Annette E.; Montenari, Michael

2016-04-01

A study on world shale reserves conducted by the Energy Information Agency (EIA) in 2013 concluded that there could be as much as 390 Tcf recoverable reserves of shale gas in the southern and south-western parts of the Karoo Basin. This would make it the 8th-largest shale gas resource in the world. However, the true extent and commercial viability is still unknown, due to the lack of exploration drilling and modern 3D seismic. Within the framework of the Karoo Research Initiative (KARIN), two deep boreholes were drilled in the Eastern and Western Cape provinces of South Africa. Here we report on new core material from borehole KZF-1 (Western Cape) which intersected the Permian black shales of the Ecca Group, the Whitehill Formation being the main target formation for future shale gas production. To determine the original source potential for shale gas we investigated the sedimentary environments in which the potential source rocks formed, addressing the research question of how much sedimentary organic matter the shales contained when they originally formed. Palynofacies indicates marginal marine conditions of a stratified basin setting with low marine phytoplankton percentages (acritarchs, prasinophytes), good AOM preservation, high terrestrial input, and a high spores:bisaccates ratio (kerogen type III). Stratigraphically, a deepening-upward trend is observed. Laterally, the basin configuration seems to be much more complex than previously assumed. Furthermore, palynological data confirms the correlation of marine black shales of the Prince Albert and Whitehill formations in the southern and south-western parts of the Karoo Basin with the terrestrial coals of the Vryheid Formation in the north-eastern part of the basin. TOC values (1-6%) classify the Karoo black shales as promising shale gas resources, especially with regard to the high thermal maturity (Ro >3). The recently drilled deep boreholes in the southern and south-western Karoo Basin, the first since the

John Martin Wood (1938-2008)--pioneering biochemist, educator and communicator.

PubMed

Tobin, Desmond J; Pittelkow, Mark R; Slominski, Andrzej

2008-07-01

John Martin Wood, Emeritus Professor of Medical Biochemistry at the University of Bradford died in Wieck by Greifswald, Germany after a short illness on February 5, 2008 - just short of his 70(th) year. John worked as a pioneering biochemist and educator in the US and in Britain across two research careers. He devoted the first twenty-five years to the role of transition metals in biology, and his last twenty-years to cutaneous enzymology and melanogenesis. Working together with his wife Professor Karin U. Schallreuter, his research on oxidative stress handling in skin and on the expression of a cutaneous catecholaminergic system will help direct research in these fields for many years to come. John impressed on his fellow cutaneous researchers and students the critical importance of appreciating the true role of enzymes in skin health and disease. This obituary aims to contextualize the significant contributions made by this remarkable man to experimental dermatology.

Women's Health Research: Current State of the Art

PubMed Central

2013-01-01

It is remarkable that only a few years ago, discussions about women's health research often had to be prefaced with the expanded vision of what that concept should actually be in totality as the traditional approach to the health of women had focused on the reproductive system or “bikini medicine,” as Dr Marianne Legato, an internationally recognized specialist in women's health, and others have characterized it. Today, there is an almost universal appreciation of the broader perception of women's health and that research on women includes not just clinical trials but also basic investigation from the molecular level of genes to the many aspects of behavioral and societal influences. This evolution over the past 25 years of what should and does constitute women's health research has been important in influencing the design of biomedical and behavioral research studies and in elucidating factors now implicit in diagnostic and therapeutic approaches to both males and females.1 And examples of advances from research providing the foundation for public health policies and legislative initiatives only strengthen the understanding of the value of these efforts.2 PMID:24416687

KARIN: The Ka-Band Radar Interferometer for the Proposed Surface Water and Ocean Topography (SWOT) Mission

NASA Technical Reports Server (NTRS)

Esteban-Fernandez, Daniel; Peral, Eva; McWatters, Dalia; Pollard, Brian; Rodriguez, Ernesto; Hughes, Richard

2013-01-01

Over the last two decades, several nadir profiling radar altimeters have provided our first global look at the ocean basin-scale circulation and the ocean mesoscale at wavelengths longer than 100 km. Due to sampling limitations, nadir altimetry is unable to resolve the small wavelength ocean mesoscale and sub-mesoscale that are responsible for the vertical mixing of ocean heat and gases and the dissipation of kinetic energy from large to small scales. The proposed Surface Water and Ocean Topography (SWOT) mission would be a partnership between NASA, CNES (Centre National d'Etudes Spaciales) and the Canadian Space Agency, and would have as one of its main goals the measurement of ocean topography with kilometer-scale spatial resolution and centimeter scale accuracy. In this paper, we provide an overview of all ocean error sources that would contribute to the SWOT mission.

Recommended guidelines for uniform reporting of pediatric advanced life support: the pediatric Utstein style.

PubMed

Zaritsky, A; Nadkarni, V; Hazinski, M F; Foltin, G; Quan, L; Wright, J; Fiser, D; Zideman, D; O'Malley, P; Chameides, L

1995-10-01

This statement is the product of a task force meeting held June 8, 1994, in Washington DC in conjunction with the First International Conference on Pediatric Resuscitation and a follow-up task force writing group meeting held September 18, 1994, in Chicago. Draft versions of the statement were circulated for comment to all members of the task force, the American Heart Association Subcommittee on Pediatric Resuscitation, and several outside reviewers. This statement and the International Conference on Pediatric Resuscitation were cosponsored by the American Academy of Pediatrics and the American Heart Association. The development of this statement was authorized by the American Academy of Pediatrics; the American Heart Association National Subcommittees on Pediatric Resuscitation, Basic Life Support, and Advanced Cardiac Life Support, the Committee on Emergency Cardiac Care, the Science Advisory Committee; and the European Resuscitation Council. In addition to the writing group, members of the Pediatric Utstein Task Force are Paul Anderson, M Douglas Baker, Jane Ball, Desmond Bohn, Dena Brownstein, J Michael Dean, Niranjan Kissoon, Bruce Klein, Patrick Malone, Karin McCloskey, James McCrory, P Pearl O'Rourke, Mary Patterson, Charles Schleien, James Seidel, Joseph J Tepas III, and Becky Yano.

Technology for communicational development and learning in psychomotor disability

NASA Astrophysics Data System (ADS)

Trento, I.; Santucci, M.; Tula, S.; González, E.

2007-11-01

The applied investigation and experimental development project described in this paper has been carried out by Grupo Ingeniería Clínica of the Universidad Tecnológica Nacional together with two Special Education Schools dependent on the Ministry of Education of Córdoba Province. Its aim is the development of computer access assistive tools for students with mobility limitations, and with or without intellectual problems that need adaptations to access to a computer in order to learn, communicate, work, etc. On the other hand, it demonstrates the benefits that the use of a computer gives to these students. The evaluation of their performance was made trough Dr. Marianne Frostig's Developmental Test of Visual Perception and reading and writing graphic tests, comparing the results of the tests made on paper with those made on computer. Thus, an interdisciplinary team was formed by Engineering, Psychology and Special Education professionals, and 40 students were evaluated. The design of the mouse and keyboard had some adaptations. At present, the rating test stage is being achieved, and the preliminary results allow us to anticipate that pupils with psychomotor disabilities may manifest their perceptual ripeness and reach education in a more efficient way through the use of informatics tools according to their needs and possibilities.

Fluid technologies: The Bush Pump, the LifeStraw and microworlds of humanitarian design.

PubMed

Redfield, Peter

2016-04-01

Over the past decade, many ingenious, small-scale gadgets have appeared in response to problems of disaster and extreme poverty. Focusing on the LifeStraw, a water filtration device invented by the company Vestergaard Frandsen, I situate this wave of humanitarian design relative to Marianne de Laet and Annemarie Mol's classic article on the Zimbabwe Bush Pump. The LifeStraw shares the Bush Pump's principle of technical minimalism, as well as its ethical desire to improve the lives of communities. Unlike the pump, however, the straw defines itself through rather than against market logic, accepting the premise that one can 'do well while doing good'. Moreover, it does not share the assumed framework of de Laet and Mol's Zimbabwean socio-technical landscape: a postcolonial state happily en route to national self-definition. Nonetheless, it clearly embodies moral affect, if in the idiom of humanitarian concern rather than development. My aim is to open up three interrelated lines of inquiry for discussion. First, I consider aspects of a postcolonial condition at the micro-level of immediate needs, including assumptions about nation-state politics and markets. Second, I emphasize science and technology in the form of infrastructure, the material frontline of norms. Third, I return reflexively to love, and the complicated allure of engagement in academic work.

Capabilities and limitations of handheld Diffuse Reflectance Infrared Fourier Transform Spectroscopy (DRIFTS) for the analysis of colourants and binders in 20th-century reverse paintings on glass

NASA Astrophysics Data System (ADS)

Steger, Simon; Stege, Heike; Bretz, Simone; Hahn, Oliver

2018-04-01

A non-invasive method has been carried out to show the capabilities and limitations of Diffuse Reflectance Infrared Fourier Transform Spectroscopy (DRIFTS) for identifying of colourants and binders in modern reverse glass paintings. For this purpose, the reverse glass paintings "Zwei Frauen am Tisch" (1920-22), "Bäume" (1946) (both by Heinrich Campendonk), "Lofoten" (1933) (Edith Campendonk-van Leckwyck) and "Ohne Titel" (1954) (Marianne Uhlenhuth), were measured. In contrast to other techniques (e.g. panel and mural painting), the paint layers are applied in reverse succession. In multi-layered paint systems, the front paint layer may no longer be accessible. The work points out the different spectral appearance of a given substance (gypsum, basic lead white) in reverse glass paintings. However, inverted bands, band overlapping and derivative-shaped spectral features can be interpreted by comparing the spectra from the paintings with spectra from pure powders and pigment/linseed oil mock-ups. Moreover, the work focuses on this method's capabilities in identifying synthetic organic pigments (SOP). Reference spectra of three common SOP (PG7, PY1, PR83) were obtained from powders and historical colour charts. We identified PR83 and PY1 in two reverse glass paintings, using the measured reference spectra. The recorded DRIFTS spectra of pure linseed oil, gum Arabic, mastic, polyvinyl acetate resin and bees wax can be used to classify the binding media of the measured paintings.

Technical-Information Products for a National Volcano Early Warning System

USGS Publications Warehouse

Guffanti, Marianne; Brantley, Steven R.; Cervelli, Peter F.; Nye, Christopher J.; Serafino, George N.; Siebert, Lee; Venezky, Dina Y.; Wald, Lisa

2007-01-01

Introduction Technical outreach - distinct from general-interest and K-12 educational outreach - for volcanic hazards is aimed at providing usable scientific information about potential or ongoing volcanic activity to public officials, businesses, and individuals in support of their response, preparedness, and mitigation efforts. Within the context of a National Volcano Early Warning System (NVEWS) (Ewert et al., 2005), technical outreach is a critical process, transferring the benefits of enhanced monitoring and hazards research to key constituents who have to initiate actions or make policy decisions to lessen the hazardous impact of volcanic activity. This report discusses recommendations of the Technical-Information Products Working Group convened in 2006 as part of the NVEWS planning process. The basic charge to the Working Group was to identify a web-based, volcanological 'product line' for NVEWS to meet the specific hazard-information needs of technical users. Members of the Working Group were: *Marianne Guffanti (Chair), USGS, Reston VA *Steve Brantley, USGS, Hawaiian Volcano Observatory HI *Peter Cervelli, USGS, Alaska Volcano Observatory, Anchorage AK *Chris Nye, Division of Geological and Geophysical Surveys and Alaska Volcano Observatory, Fairbanks AK *George Serafino, National Oceanic and Atmospheric Administration, Camp Springs MD *Lee Siebert, Smithsonian Institution, Washington DC *Dina Venezky, USGS, Volcano Hazards Team, Menlo Park CA *Lisa Wald, USGS, Earthquake Hazards Program, Golden CO

Meeting report VLPNPV: Sessions 1 and 2: Plenary.

PubMed

Sainsbury, Frank

2014-01-01

Following the highly successful inaugural meeting in 2012, the second installment of Virus-Like Particles and Nano-Particle Vaccines (VLPNPV), proved to be a worthy follow-up in an outstanding conference series. VLPNPV is a forum for academics and industry to address one of the major areas of need in biomedical sciences, the development of novel prophylactic and therapeutic vaccines. The conference was opened by Professor Marianne Manchester of the University of California, San Diego who pointed to the significance of the site chosen for the conference, the Salk Institute. Founded by Jonas Salk, the Salk Institute for Biological Studies is a non-profit, independent research institute with focuses in molecular biology and genetics, neurosciences, and plant biology. This diversity in research themes reflects the wishes of the institute's founder who saw value in using interdisciplinary approaches to understanding the basic principles in life, aimed at generating new therapies and treatments for human disease. Likewise, interdisciplinarity was reflected in the main themes of the meeting, which also highlight some of the potential advantages of virus-like particle (VLP) and nanoparticle vaccines, including novel formulations/adjuvanting effects, structurally accurate/designed antigens, production systems and capacity, and tailoring the immune response. These themes were covered by the 2 plenary sessions that opened the conference and are described in this report.

WatER: The proposed Water Elevation Recovery satellite mission

NASA Astrophysics Data System (ADS)

Alsdorf, D.; Mognard, N.; Rodriguez, E.; Participants, W.

2005-12-01

Surface fresh water is essential for life, yet we have surprisingly poor knowledge of the spatial and temporal dynamics of surface water storage and discharge globally. The core mission objective is to describe and understand the continental water cycle and the hydrological processes (e.g., floodplain hydraulics) at work in a river basin. The key question that will be answered by WatER is: "Where is water stored on Earth's land surfaces, and how does this storage vary in space and time?" WatER will facilitate societal needs by (1) improving our understanding of flood hazards; (2) freely providing water volume information to countries who critically rely on rivers that cross political borders; and (3) mapping the variations in water bodies that contribute to disease vectors (e.g., malaria). Conventional altimeter profiles are, without question, incapable of supplying the measurements needed to address scientific and societal questions. WatER will repeatedly measure the spatially distributed water surface elevations (h) of wetlands, rivers, lakes, reservoirs, etc. Successive h measurements yield dh/dt, (t is time), hence a volumetric change in water stored or lost. Individual images of h yield dh/dx (x is distance), hence surface water slope, which is necessary for estimating streamflow. WatER's main instrument is a Ka-band radar interferometer (KaRIN) which is the only technology capable of supplying the required imaging capability of h. KaRIN has a rich heritage based on (1) the many highly successful ocean observing radar altimeters, (2) the Shuttle Radar Topography Mission (SRTM), and (3) the development effort of the Wide Swath Ocean Altimeter (WSOA). The interferometric altimeter is a near-nadir viewing, 120 km wideswath based instrument that uses interferometric SAR processing of the returned pulses to yield single-look 5m azimuth and 10m to 70m range resolution, with an elevation accuracy of approximately 50 cm. Polynomial based averaging of heights along the

Seismic Hazard in Haiti: A Geologic Perspective

NASA Astrophysics Data System (ADS)

Prentice, C. S.; Crone, A. J.; Gold, R. D.; Briggs, R. W.; Narcisse, R.

2012-12-01

The catastrophic M 7.0 earthquake that occurred in Haiti on 12 January 2010 highlighted the hazard associated with the Caribbean-North American plate boundary in Hispaniola. Detailed analysis and modeling of geologic, geodetic, and seismologic data showed that most of the moment release occurred on a previously unidentified, north-dipping, blind thrust fault (now named the Léogâne fault), which is north of the plate-bounding, left-lateral Enriquillo-Plantain Garden fault (EPGF). The result that the Léogâne fault was the source of the 2010 earthquake implies that the EPGF remains a significant hazard and raises the question of other potential seismic sources near Port-au-Prince (PaP). Following the earthquake, we mapped Quaternary traces of the EPGF in the field using satellite imagery, aerial photography, and LiDAR data. We identified three paleoseismic study sites along the EPGF: the Jean-Jean and Marianne sites southwest of PaP along the Momance section of the EPGF and the Riviére Grise site southeast of PaP along the Dumay section. Trenches at the Jean-Jean site show fault strands breaking nearly to the ground surface, but that did not move in the 2010 earthquake. We collected radiocarbon samples from faulted strata that we anticipate will provide constraints on the age of the most recent surface rupture. We also identified a buried channel deposit that is left-laterally offset a minimum of 3 m, and collected radiocarbon samples to constrain its age. In a natural stream cut at the Marianne site, we documented three colluvial wedges, and collected samples for optically stimulated luminescence (OSL) dating that we anticipate will provide age constraints on the three most recent earthquakes. At Riviére Grise we documented evidence for three surface ruptures in a fluvial terrace deposit, and collected OSL samples to constrain their ages. Our preliminary geomorphic analysis of a belt of low hills north of the EPGF and east of PaP suggests that these hills are

New Techniques for Radar Altimetry of Sea Ice and the Polar Oceans

NASA Astrophysics Data System (ADS)

Armitage, T. W. K.; Kwok, R.; Egido, A.; Smith, W. H. F.; Cullen, R.

2017-12-01

Satellite radar altimetry has proven to be a valuable tool for remote sensing of the polar oceans, with techniques for estimating sea ice thickness and sea surface height in the ice-covered ocean advancing to the point of becoming routine, if not operational, products. Here, we explore new techniques in radar altimetry of the polar oceans and the sea ice cover. First, we present results from fully-focused SAR (FFSAR) altimetry; by accounting for the phase evolution of scatterers in the scene, the FFSAR technique applies an inter-burst coherent integration, potentially over the entire duration that a scatterer remains in the altimeter footprint, which can narrow the effective along track resolution to just 0.5m. We discuss the improvement of using interleaved operation over burst-more operation for applying FFSAR processing to data acquired by future missions, such as a potential CryoSat follow-on. Second, we present simulated sea ice retrievals from the Ka-band Radar Interferometer (KaRIn), the instrument that will be launched on the Surface Water and Ocean Topography (SWOT) mission in 2021, that is capable of producing swath images of surface elevation. These techniques offer the opportunity to advance our understanding of the physics of the ice-covered oceans, plus new insight into how we interpret more conventional radar altimetry data in these regions.

Discharge estimation in ungauged basins through variational data assimilation : The potential of the SWOT mission.

NASA Astrophysics Data System (ADS)

Oubanas, H.; Gejadze, I.; Malaterre, P. O.; Durand, M. T.; Wei, R.; Frasson, R. P. M.; Domeneghetti, A.

2017-12-01

This work investigates the estimation of river discharge from simulated observations of the forthcoming Surface Water and Ocean Topography (SWOT) mission, to be launched in 2021, using a variant of the standard variational data assimilation method `4D-Var'. The hydrology SWOT simulator, developed at the Jet Propulsion Laboratory (JPL) has been used to simulate the expected performance of the KaRIn instrument onboard the satellite, producing synthetic SWOT observations of height and width, at each satellite overpass. SWOT data products were synthesized at the spatial scale of 200 m along the river centerline. Using a 1.5D full Saint-Venant hydraulic model, variational data assimilation simultaneously estimates the inflow discharge, river bathymetry and bed roughness. The proposed method has been designed for an application to fully ungauged basins; therefore, the prior information is derived from the SWOT observations only and the globally available ancillary information. Two reaches of the Po and Sacramento Rivers of about 130 km and 150 km, respectively, have been considered in this study. Discharge was successfully recovered at the overpass time with a relative-root-mean-square error of 16% and 12.3% for the Po and Sacramento Rivers, respectively. The estimates of the bed level and the roughness coefficient demonstrate a local improvement; however they may not provide reliable global information of the river bathymetry and roughness.

Capabilities and limitations of handheld Diffuse Reflectance Infrared Fourier Transform Spectroscopy (DRIFTS) for the analysis of colourants and binders in 20th-century reverse paintings on glass.

PubMed

Steger, Simon; Stege, Heike; Bretz, Simone; Hahn, Oliver

2018-04-15

A non-invasive method has been carried out to show the capabilities and limitations of Diffuse Reflectance Infrared Fourier Transform Spectroscopy (DRIFTS) for identifying of colourants and binders in modern reverse glass paintings. For this purpose, the reverse glass paintings "Zwei Frauen am Tisch" (1920-22), "Bäume" (1946) (both by Heinrich Campendonk), "Lofoten" (1933) (Edith Campendonk-van Leckwyck) and "Ohne Titel" (1954) (Marianne Uhlenhuth), were measured. In contrast to other techniques (e.g. panel and mural painting), the paint layers are applied in reverse succession. In multi-layered paint systems, the front paint layer may no longer be accessible. The work points out the different spectral appearance of a given substance (gypsum, basic lead white) in reverse glass paintings. However, inverted bands, band overlapping and derivative-shaped spectral features can be interpreted by comparing the spectra from the paintings with spectra from pure powders and pigment/linseed oil mock-ups. Moreover, the work focuses on this method's capabilities in identifying synthetic organic pigments (SOP). Reference spectra of three common SOP (PG7, PY1, PR83) were obtained from powders and historical colour charts. We identified PR83 and PY1 in two reverse glass paintings, using the measured reference spectra. The recorded DRIFTS spectra of pure linseed oil, gum Arabic, mastic, polyvinyl acetate resin and bees wax can be used to classify the binding media of the measured paintings. Copyright © 2018 Elsevier B.V. All rights reserved.

Using Sentinel-2A multispectral imagery to explore for deep groundwater resources in the Ceres-Tankwa Karoo, Western Cape, South Africa: Significance for the 'water-energy(-food) nexus' in an arid region

NASA Astrophysics Data System (ADS)

Hartnady, Chris; Wise, Edward; Hartnady, Michael; Olianti, Camille; Hay, E. Rowena

2017-04-01

warming and increasing water scarcity in semi-arid regions, deep artesian groundwater systems provide a long-term solution to future demands for water, food and power. In contrast to shale-gas development, which competes for the scarce water resource and poses a substantial pollution threat, an alternative, synergistic and conjunctive development of solar energy, specifically Concentrating Solar Power plants facilitated by the deep artesian groundwater resource, is envisaged for the Ceres-Tankwa and other parts of the Southern Karoo, in a proposed "Sores-Kamma (Sun-Water) Initiative". In this effort, Sentinel-2A-based lithological mapping is integrated with a new digital elevation model, providing geomorphometry and morphotectonic interpretations, and with the systematic monitoring of surface- and groundwater fluxes using a conjunction of radar satellite, Global Navigation Satellite Systems and microgravity approaches. Reference De Kock, M.O., Beukes, N.J., Götz, A.E., Cole, D., Birch, A., Withers, A. and Van Niekerk, H.S. 2016. Open file progress report on exploration of the southern Karoo Basin through CIMERA-KARIN borehole KZF-1 in the Tankwa Karoo, Witzenberg (Ceres) District. 12 pp. Available online at http://www.cimera.co.za/index.php/karin-feedback

A Steinian approach to an empathic understanding of hope among patients and clinicians in the culture of palliative care.

PubMed

Richardson, Kate; Macleod, Rod; Kent, Bridie

2012-03-01

This article presents a discussion of empathy in the context of human person, reason and hopes in the clinical setting. Empathy was introduced to nursing as part of an ethical and philosophical foundation for caring. It helped to solve the tension and meet the demands that empathy placed upon nursing practice. This article is based on two studies undertaken between 2008 and 2010 to understand the concept of hope and empathy among people with terminal cancer and doctors who care for them. Doctoral dissertations and theses of Edith Stein (1916-1917), Marianne Sawicki [Body, Text and Science. The Literary of Investigative Practices and the Phenomenology of Edith Stein (1997) Kluwer Academic Publisher, Dordrecht], and Sister M. Judith Parsons (2005) have been used to examine: 'the essence of acts of empathy', 'the constitution of the psycho-physical individual' and 'empathy as understanding of intellectual persons'. CINAHL, MEDLINE and PROQUEST have provided further supporting data. Discussion.  Steinian empathy requires that we use affective resonance, cognitive understanding and distance, as we grasp another person's emotional and situational reality while in the caring role as nurses. Implications for current nursing.  Steinian empathy is about recognizing a lived experience and standing side-by-side with that person. Nurses can transmit this knowledge to enable and support courage and wisdom to reduce feelings of helplessness when caring for people with terminal illness. Not only is empathy a safe and permissible emotion, it is the linchpin to a caring patient-nurse relationship and we must embrace this. © 2011 Blackwell Publishing Ltd.

2012 Aspen Winter Conference New Paradigms for Low-Dimensional Electronic Materials, February 5-10, 2012

DOE Office of Scientific and Technical Information (OSTI.GOV)

Moore, Joel; Rabe, Karin; Nayak, Chetan

2012-05-01

Aspen Center for Physics Project Summary DOE Budget Period: 10/1/2011 to 9/30/2012 Contract # DE-SC0007479 New Paradigms for Low-Dimensional Electronic Materials The 2012 Aspen Winter Conference on Condensed Matter Physics was held at the Aspen Center for Physics from February 5 to 10, 2012. Seventy-four participants from seven countries, and several universities and national labs attended the workshop titled, New Paradigms for Low-Dimensional Electronic Materials. There were 34 formal talks, and a number of informal discussions held during the week. Talks covered a variety of topics related to DOE BES priorities, including, for example, advanced photon techniques (Hasan, Abbamonte, Orenstein,more » Shen, Ghosh) and predictive theoretical modeling of materials properties (Rappe, Pickett, Balents, Zhang, Vanderbilt); the full conference schedule is provided with this report. The week's events included a public lecture (Quantum Matters given by Chetan Nayak from Microsoft Research) and attended by 234 members of the public, and a physics caf© geared for high schoolers that is a discussion with physicists conducted by Kathryn Moler (Stanford University) and Andrew M. Rappe (University of Pennsylvania) and attended by 67 locals and visitors. While there were no published proceedings, some of the talks are posted online and can be Googled. The workshop was organized by Joel Moore (University of California Berkeley), Chetan Nayak (Microsoft Research), Karin Rabe (Rutgers University), and Matthias Troyer (ETH Zurich). Two organizers who did not attend the conference were Gabriel Aeppli (University College London & London Centre for Nanotechnology) and Andrea Cavalleri (Oxford University & Max Planck Hamburg).« less

Who owns the long term? Perspectives from global business leaders.

PubMed

Lévy, Maurice; Eskew, Mike; Bernotat, Wulf H; Barner, Marianne

2007-01-01

Day-to-day management is challenging enough for CEOs. How do they manage for the long term as well? We posed that question to four top executives of global companies. According to Maurice Levy, chairman and CEO of Publicis Groupe, building the future is really about building the present and keeping close to the front line--those who deal with your customers and markets. He also attributes his company's success in large part to knowing when to take action: In a market where clients' needs steer your long-term future, timing is everything. UPS Chairman and CEO Mike Eskew emphasizes staying true to your vision and values over the long run, despite meeting obstacles along the way. It took more than 20 years, and many lessons learned, to produce consistent profits in what is today the company's fastest-growing and most profitable business: international small packages. Wulf H. Bernotat, CEO of E.ON, examines the challenges facing business leaders and politicians as they try to balance energy needs against potential environmental damage. He calls for educating people about consumption and waste, and he maintains that a diverse and reliable mix of energy sources is the only way to ensure a secure supply while protecting our environment. Finally, Marianne Barner, the director of corporate communications and ombudsman for children's issues at IKEA, discusses how the company is taking steps to improve the environment and be otherwise socially responsible. For example, it's partnering with NGOs to address child labor issues and, on its own, is working to help mitigate climate change. IKEA's goals include using renewable sources for 100% of its energy needs and cutting its overall energy consumption by 25%.

Mapping Extinction and Star Formation Rates of Nearby Galaxies

NASA Astrophysics Data System (ADS)

Ridenour, Anthony; Takamiya, M.

2010-01-01

Star Formation Rate (SFR) is a physical characteristic of galaxies vital to our understanding of such problems as the evolution of the Universe. In computing SFRs obscuring dust systematically lowers them at shorter wavelengths compared to longer wavelengths. This issue of dust extinction has been handled well by multi-wavelength studies of nearby galaxies. Star Formation Rate measurements of distant galaxies are currently reliant on the emission of visible spectroscopic lines like Hα and [OII] after correction for extinction. However, if the visible light is completely obscured an incorrect assumption may be drawn; namely that there is neither SFR nor extinction. The work purposed here is to calibrate the SFR ascertained from Hα emission in nearby galaxies and compare it to radio and infrared emission. The Balmer decrement, or the ratio of Hβ to Hα emission, used to determine extinction, will also be studied and compared to infrared images. 30 nearby galaxies will be sampled and 2-D maps and Balmer decrements will be formed to do two things: measure SFRs and determine differences between Hα and infrared emission, and explore in what ways this difference corresponds with such things as the radio SFR, galaxy luminosity and morphological type. The accuracy of Hα as a SFR indicator and its determination as a sound tool in measuring SFRs of distant galaxies can both be quantified by interpreting these maps. Dr. Marianne Takamiya, the principal investigator and my mentor, secured funds through a grant to the University of Hawai'i at Hilo from The Research Corporation for Science Advancement Cottrell College Science Awards for this research.

Well-ordered science and Indian epistemic cultures: toward a polycentered history of science.

PubMed

Ganeri, Jonardon

2013-06-01

This essay defends the view that "modern science," as with modernity in general, is a polycentered phenomenon, something that appears in different forms at different times and places. It begins with two ideas about the nature of rational scientific inquiry: Karin Knorr Cetina's idea of "epistemic cultures," and Philip Kitcher's idea of science as "a system of public knowledge," such knowledge as would be deemed worthwhile by an ideal conversation among the whole public under conditions of mutual engagement. This account of the nature of scientific practice provides us with a new perspective from which to understand key elements in the philosophical project of Jaina logicians in the seventh, eighth, and ninth centuries C.E. Jaina theory seems exceptionally well targeted onto two of the key constituents in the ideal conversation--the classification of all human points of view and the representation of end states of the deliberative process. The Buddhist theory of the Kathāvatthu contributes to Indian epistemic culture in a different way: by supplying a detailed theory of how human dialogical standpoints can be revised in the ideal conversation, an account of the phenomenon Kitcher labels "tutoring." Thus science in India has its own history, one that should be studied in comparison and contrast with the history of science in Europe. In answer to Joseph Needham, it was not 'modern science' which failed to develop in India or China but rather non-well-ordered science, science as unconstrained by social value and democratic consent. What I argue is that this is not a deficit in the civilisational histories of these countries, but a virtue.

The Praise and Price of Pokémon GO: A Qualitative Study of Children's and Parents' Experiences.

PubMed

Lindqvist, Anna-Karin; Castelli, Darla; Hallberg, Josef; Rutberg, Stina

2018-01-03

Physical activity has multiple health benefits; however, the majority of children around the world do not attain the recommended levels of daily physical activity. Research has shown that the game Pokémon GO has increased the amount of physical activity of players and that the game has the potential to reach populations that traditionally have low levels of physical activity. Therefore, there is a need to understand which game components can promote initial and sustained physical activity. By using a qualitative research approach, it is possible to achieve rich descriptions and enhance a deep understanding of the components promoting physical activity among children in a game such as Pokémon GO. The objective of this study was to explore children's and parents' experiences playing Pokémon GO. Eight families comprising 13 children (aged 7-12 years) and 9 parents were selected using purposeful sampling. Data collected using focus groups were analyzed using qualitative latent content analysis. The following three themes were revealed: (1) exciting and enjoyable exploration; (2) dangers and disadvantages; and (3) cooperation conquers competition. The first centers around the present and possible future aspects of Pokémon GO that promote physical activity. The second focuses on unwanted aspects and specific threats to safety when playing the game. The third shows that cooperation and togetherness are highly valued by the participants and that competition is fun but less important. Components from Pokémon GO could enhance the efficacy of physical activity interventions. Cooperation and exploration are aspects of the game that preferably could be transferred into interventions aimed at promoting children's physical activity. ©Anna-Karin Lindqvist, Darla Castelli, Josef Hallberg, Stina Rutberg. Originally published in JMIR Serious Games (http://games.jmir.org), 03.01.2018.

Common Ground on Climate Change: Pairing Opposing Viewpoints for Conversations about Climate Change

NASA Astrophysics Data System (ADS)

Kirk, K. B.; Duggan-Haas, D.; Hayhoe, K.

2017-12-01

In American public discourse, people tend to strongly identify with the viewpoints held by their cultural and political tribes. However, entrenched positions do little to advance understanding, or work toward solving problems constructively. Worse yet, it has become commonplace to dismiss or demonize those coming from a different point of view - leading to the vitriolic stalemate that often characterizes social media and comment threads when it comes to climate change. One way to break this pattern is to invite people with opposing opinions to actually talk to one another. This presentation describes the lessons learned during the Common Ground on Climate Change project, in which people with contrasting views about climate change engage in a moderated interview with each other. Prior to the interview, participants complete a set of values-based questions. The goal is to reveal areas of common ground between apparent opposites, such as a sense of stewardship for Earth's resources, or an opinion that solutions to climate change will be more beneficial than harmful. The structure of the interviews is based on the hypothesis that if a conversation begins with an appreciation of common values, it becomes easier to broach areas of disagreement. Participants are matched up in one-on-one moderated interviews where they are encouraged to share their concerns, ideas, and priorities about the validity of climate science, the need for urgent action, and the types of solutions they find most tenable. Emerging themes from this series of interviews include the value of a diversity of outlooks, and the ability for moderated conversations to find surprising areas of agreement. Articles about the interviews also appear on the Yale Climate Connections website, https://www.yaleclimateconnections.org/author/karin/.

Controlling cytoplasmic c-Fos controls tumor growth in the peripheral and central nervous system.

PubMed

Gil, Germán A; Silvestre, David C; Tomasini, Nicolás; Bussolino, Daniela F; Caputto, Beatriz L

2012-06-01

Some 20 years ago c-Fos was identified as a member of the AP-1 family of inducible transcription factors (Angel and Karin in Biochim Biophys Acta 1072:129-157, 1991). More recently, an additional activity was described for this protein: it associates to the endoplasmic reticulum and activates the biosynthesis of phospholipids (Bussolino et al. in FASEB J 15:556-558, 2001), (Gil et al. in Mol Biol Cell 15:1881-1894, 2004), the quantitatively most important components of cellular membranes. This latter activity of c-Fos determines the rate of membrane genesis and consequently of growth in differentiating PC12 cells (Gil et al. in Mol Biol Cell 15:1881-1894, 2004). In addition, it has been shown that c-Fos is over-expressed both in PNS and CNS tumors (Silvestre et al. in PLoS One 5(3):e9544, 2010). Herein, it is shown that c-Fos-activated phospholipid synthesis is required to support membrane genesis during the exacerbated growth characteristic of brain tumor cells. Specifically blocking c-Fos-activated phospholipid synthesis significantly reduces proliferation of tumor cells in culture. Blocking c-Fos expression also prevents tumor progression in mice intra-cranially xeno-grafted human brain tumor cells. In NPcis mice, an animal model of the human disease Neurofibromatosis Type I (Cichowski and Jacks in Cell 104:593-604, 2001), animals spontaneously develop tumors of the PNS and the CNS, provided they express c-Fos (Silvestre et al. in PLoS One 5(3):e9544, 2010). Treatment of PNS tumors with an antisense oligonucleotide that specifically blocks c-Fos expression also blocks tumor growth in vivo. These results disclose cytoplasmic c-Fos as a new target for effectively controlling brain tumor growth.

Lunar and Planetary Science XXXVI, Part 18

NASA Technical Reports Server (NTRS)

2005-01-01

Topics discussed include: PoDS: A Powder Delivery System for Mars In-Situ Organic, Mineralogic and Isotopic Analysis Instruments Planetary Differentiation of Accreting Planetesimals with 26Al and 60Fe as the Heat Sources Ground-based Observation of Lunar Surface by Lunar VIS/NIR Spectral Imager Mt. Oikeyama Structure: First Impact Structure in Japan? Central Mounds in Martian Impact Craters: Assessment as Possible Perennial Permafrost Mounds (Pingos) A Further Analysis of Potential Photosynthetic Life on Mars New Insight into Valleys-Ocean Boundary on Mars Using 128 Pixels per Degree MOLA Data: Implication for Martian Ocean and Global Climate Change; Recursive Topography Based Surface Age Computations for Mars: New Insight into Surficial Processes That Influenced Craters Distribution as a Step Toward the Formal Proof of Martian Ocean Recession, Timing and Probability; Laser-induced Breakdown Spectroscopy: A New Method for Stand-Off Quantitative Analysis of Samples on Mars; Milk Spring Channels Provide Further Evidence of Oceanic, >1.7-km-Deep Late Devonian Alamo Crater, Southern Nevada; Exploration of Martian Polar Residual Caps from HEND/ODYSSEY Data; Outflow Channels Influencing Martian Climate: Global Circulation Model Simulations with Emplaced Water; Presence of Nonmethane Hydrocarbons on Pluto; Difference in Degree of Space Weathering on the Newborn Asteroid Karin; Circular Collapsed Features Related to the Chaotic Terrain Formation on Mars; A Search for Live (sup 244)Pu in Deep-Sea Sediments: Preliminary Results of Method Development; Some Peculiarities of Quartz, Biotite and Garnet Transformation in Conditions of Step-like Shock Compression of Crystal Slate; Error Analysis of Remotely-Acquired Mossbauer Spectra; Cloud Activity on Titan During the Cassini Mission; Solar Radiation Pressure and Transient Flows on Asteroid Surfaces; Landing Site Characteristics for Europa 1: Topography; and The Crop Circles of Europa.

Bringing radical behaviorism to revolutionary Brazil and back: Fred Keller's Personalized System of Instruction and Cold War engineering education.

PubMed

Akera, Atsushi

2017-09-01

This article traces the shifting epistemic commitments of Fred S. Keller and his behaviorist colleagues during their application of Skinnerian radical behaviorism to higher education pedagogy. Building on prior work by Alexandra Rutherford and her focus on the successive adaptation of Skinnerian behaviorism during its successive applications, this study utilizes sociologist of science Karin Knorr Cetina's concept of epistemic cultures to more precisely trace the changes in the epistemic commitments of a group of radical behaviorists as they shifted their focus to applied behavioral analysis. The story revolves around a self-paced system of instruction known as the Personalized System of Instruction, or PSI, which utilized behaviorist principles to accelerate learning within the classroom. Unlike Skinner's entry into education, and his focus on educational technologies, Keller developed a mastery-based approach to instruction that utilized generalized reinforcers to cultivate higher-order learning behaviors. As it happens, the story also unfolds across a rather fantastic political terrain: PSI originated in the context of Brazilian revolutionary history, but circulated widely in the U.S. amidst Cold War concerns about an engineering manpower(sic) crisis. This study also presents us with an opportunity to test Knorr Cetina's conjecture about the possible use of a focus on epistemic cultures in addressing a classic problem in the sociology of science, namely unpacking the relationship between knowledge and its social context. Ultimately, however, this study complements another historical case study in applied behavioral analysis, where a difference in outcome helps to lay out the range of possible shifts in the epistemic commitments of radical behaviorists who entered different domains of application. The case study also has some practical implications for those creating distance learning environments today, which are briefly explored in the conclusion. © 2017 Wiley

Multiverse: Increasing Diversity in Earth and Space Science Through Multicultural Education

NASA Astrophysics Data System (ADS)

Peticolas, L. M.; Raftery, C. L.; Mendez, B.; Paglierani, R.; Ali, N. A.; Zevin, D.; Frappier, R.; Hauck, K.; Shackelford, R. L., III; Yan, D.; Thrall, L.

2015-12-01

Multiverse at the University of California, Berkeley Space Sciences Laboratory provides earth and space science educational opportunities and resources for a variety of audiences, especially for those who are underrepresented in the sciences. By way of carefully crafted space and earth science educational opportunities and resources, we seek to connect with people's sense of wonder and facilitate making personal ties to science and the learning process in order to, ultimately, bring the richness of diversity to science and make science discovery accessible for all. Our audiences include teachers, students, education and outreach professionals, and the public. We partner with NASA, the National Science Foundation, scientists, teachers, science center and museum educators, park interpreters, and others with expertise in reaching particular audiences. With these partners, we develop resources and communities of practice, offer educator workshops, and run events for the public. We will will present on our pedagogical techniques, our metrics for success, and our evaluation findings of our education and outreach projects that help us towards reaching our vision: We envision a world filled with science literate societies capable of thriving with today's technology, while maintaining a sustainable balance with the natural world; a world where people develop and sustain the ability to think critically using observation and evidence and participate authentically in scientific endeavors; a world where people see themselves and their culture within the scientific enterprise, and understand science within the context that we are all under one sky and on one Earth. Photo Caption: Multiverse Team Members at our Space Sciences Laboratory from left to right: Leitha Thrall, Daniel Zevin, Bryan Mendez, Nancy Ali, Igor Ruderman, Laura Peticolas, Ruth Paglierani, Renee Frappier, Rikki Shackelford, Claire Raftery, Karin Hauck, and Darlene Yan.

NASA Tech Briefs, December 2011

NASA Technical Reports Server (NTRS)

2011-01-01

Topics covered include: 1) SNE Industrial Fieldbus Interface; 2) Composite Thermal Switch; 3) XMOS XC-2 Development Board for Mechanical Control and Data Collection; 4) Receiver Gain Modulation Circuit; 5) NEXUS Scalable and Distributed Next-Generation Avionics Bus for Space Missions; 6) Digital Interface Board to Control Phase and Amplitude of Four Channels; 7) CoNNeCT Baseband Processor Module; 8) Cryogenic 160-GHz MMIC Heterodyne Receiver Module; 9) Ka-Band, Multi-Gigabit-Per-Second Transceiver; 10) All-Solid-State 2.45-to-2.78-THz Source; 11) Onboard Interferometric SAR Processor for the Ka-Band Radar Interferometer (KaRIn); 12) Space Environments Testbed; 13) High-Performance 3D Articulated Robot Display; 14) Athena; 15) In Situ Surface Characterization; 16) Ndarts; 17) Cryo-Etched Black Silicon for Use as Optical Black; 18) Advanced CO2 Removal and Reduction System; 19) Correcting Thermal Deformations in an Active Composite Reflector; 20) Umbilical Deployment Device; 21) Space Mirror Alignment System; 22) Thermionic Power Cell To Harness Heat Energies for Geothermal Applications; 23) Graph Theory Roots of Spatial Operators for Kinematics and Dynamics; 24) Spacesuit Soft Upper Torso Sizing Systems; 25) Radiation Protection Using Single-Wall Carbon Nanotube Derivatives; 26) PMA-PhyloChip DNA Microarray to Elucidate Viable Microbial Community Structure; 27) Lidar Luminance Quantizer; 28) Distributed Capacitive Sensor for Sample Mass Measurement; 29) Base Flow Model Validation; 30) Minimum Landing Error Powered-Descent Guidance for Planetary Missions; 31) Framework for Integrating Science Data Processing Algorithms Into Process Control Systems; 32) Time Synchronization and Distribution Mechanisms for Space Networks; 33) Local Estimators for Spacecraft Formation Flying; 34) Software-Defined Radio for Space-to-Space Communications; 35) Reflective Occultation Mask for Evaluation of Occulter Designs for Planet Finding; and 36) Molecular Adsorber Coating

Hydrogenation of benzaldehyde via electrocatalysis and thermal catalysis on carbon-supported metals

DOE Office of Scientific and Technical Information (OSTI.GOV)

Song, Yang; Sanyal, Udishnu; Pangotra, Dhananjai

Abstract Selective reduction of benzaldehyde to benzyl alcohol on C-supported Pt, Rh, Pd, and Ni in aqueous phase was conducted using either directly H2 (thermal catalytic hydrogenation, TCH) or in situ electrocatalytically generated hydrogen (electrocatalytic hydrogenation, ECH). In TCH, the intrinsic activity of the metals at room temperature and 1 bar H2 increased in the sequence Rh/C < Pt/C < Pd/C, while Ni/C is inactive at these conditions due to surface oxidation in the absence of cathodic potential. The reaction follows a Langmuir-Hinshelwood mechanism with the second hydrogen addition to the adsorbed hydrocarbon being the rate-determining step. All tested metalsmore » were active in ECH of benzaldehyde, although hydrogenation competes with the hydrogen evolution reaction (HER). The minimum cathodic potentials to obtain appreciable ECH rates were identical to the onset potentials of HER. Above this onset, the relative rates of H reacting to H2 and H addition to the hydrocarbon determines the selectivity to ECH and TCH. Accordingly, the selectivity of the metals towards ECH increases in the order Ni/C < Pt/C < Rh/C < Pd/C. Pd/C shows exceptionally high ECH selectivity due to its surprisingly low HER reactivity under the reaction conditions. Acknowledgements The authors would like to thank the groups of Hubert A. Gasteiger at the Technische Universität München of Jorge Gascon at the Delft University of Technology for advice and valuable discussions. The authors are grateful to Nirala Singh, Erika Ember, Gary Haller, and Philipp Rheinländer for fruitful discussions. We are also grateful to Marianne Hanzlik for TEM measurements and to Xaver Hecht and Martin Neukamm for technical support. Y.S. would like to thank the Chinese Scholarship Council for the financial support. The research described in this paper is part of the Chemical Transformation Initiative at Pacific Northwest National Laboratory (PNNL), conducted under the Laboratory Directed Research and

Sustainable Seas Student Intertidal Monitoring Project at Duxbury Reef in Bolinas, CA (Invited)

NASA Astrophysics Data System (ADS)

Soave, K.; Dean, A.; Darakananda, K.; Ball, O.; Butti, C.; Yang, G.; Vetter, M.; Grimaldi, Z.

2009-12-01

Sustainable Seas Student Intertidal Monitoring Project at Duxbury Reef in Bolinas, CA Kathy Soave, Amy Dean, Olivia Ball, Karin Darakananda, Matt Vetter, Grant Yang, Charlotte Butti, Zoe Grimaldi The Sustainable Seas Student Monitoring Project at the Branson School in Ross, CA has monitored Duxbury Reef in Bolinas, CA since 1999, in cooperation with the Farallones Marine Sanctuary Association and the Gulf of Farallones National Marine Sanctuary. Goals of the project include: 1) To monitor the rocky intertidal habitat and develop a baseline database of invertebrates and algal density and abundance; 2) To contribute to the conservation of the rocky intertidal habitat through education of students and visitors about intertidal species and the requirements for maintaining a healthy, diverse intertidal ecosystem; 3) To increase stewardship in the Gulf of the Farallones National Marine Sanctuary; and 4) To contribute abundance and population data on key algae and invertebrate species to the national database, LiMPETS (Long Term Monitoring Program & Experiential Training for Students). Student volunteers complete an intensive training course on the natural history of intertidal invertebrates and algae, identification of key species, rocky intertidal monitoring techniques, and history of the sanctuary. Students identify and count key invertebrate and algae species along two permanent transects (A and B) and using randomly determined points within a permanent 100 m2 area, three times per year (fall, winter, and late spring). Using the data collected since 2004, we will analyze the population densities, seasonal abundance and long-term population trends of key algal and invertebrate species. Future analyses and investigations will include intertidal abiotic factors (including water temperature and human foot-traffic) to enhance insights into the workings of the Duxbury Reef ecosystem, in particular, the high intertidal zone which experiences the greatest amount of human

Ridge interaction features of the Line Islands

NASA Astrophysics Data System (ADS)

Konter, J. G.; Koppers, A. A. P.; Storm, L. P.

2016-12-01

The sections of Pacific absolute plate motion history that precede the Hawaii-Emperor and Louisville chains are based on three chains: the Line Islands-Mid-Pacific Mountains, the Hess Rise-Shatsky Rise, and the Marshall Islands-Wake Islands (Rurutu hotspot). Although it has been clear that the Line Islands do not define a simple age progression (e.g. Schlanger et al., 1984), the apparent similarity to the Emperor Seamount geographic trend has been used to extend the overall Hawaii-Emperor track further into the past. However, we show here that plate tectonic reconstructions suggest that the Mid-Pacific Mountains (MPMs) and Line Islands (LIs) were erupted near a mid-ocean ridge, and thus these structures do not reflect absolute plate motion. Moverover, the morphology and geochemistry of the volcanoes show similarities with Pukapuka Ridge (e.g. Davis et al., 2002) and the Rano Rahi seamounts, presumed to have a shallow origin. Modern 40Ar/39Ar ages show that the LIs erupted at various times along the entire volcanic chain. The oldest structures formed within 10 Ma of plate formation. Given the short distance to the ridge system, large aseismic volcanic ridges, such as Necker Ridge and Horizon Guyot may simply reflect a connection between MPMs and the ridge, similar to the Pukapuka Ridge. The Line Islands to the south (including Karin Ridge) define short subchains of elongated seamounts that are widespread, resembling the Rano Rahi seamount field. During this time, the plate moved nearly parallel to the ridge system. The change from few large ridges to many subchains may reflect a change in absolute plate motion, similar to the Rano Rahi field. Here, significant MPMs volcanism is no longer connected to the ridge along plate motion. Similar to Pukapuka vs. Rano Rahi, the difference in direction between plate motion and the closest ridge determines whether larger ridges or smaller seamount subchains are formed. The difference between the largest structures (MPMs and LIs

Festive Nebulas Light Up Milky Way Galaxy Satellite

NASA Image and Video Library

2017-12-08

NASA’s Hubble Space Telescope captured two festive-looking nebulas, situated so as to appear as one. They reside in the Small Magellanic Cloud, a dwarf galaxy that is a satellite of our Milky Way galaxy. Intense radiation from the brilliant central stars is heating hydrogen in each of the nebulas, causing them to glow red. The nebulas, together, are called NGC 248. They were discovered in 1834 by the astronomer Sir John Herschel. NGC 248 is about 60 light-years long and 20 light-years wide. It is among a number of glowing hydrogen nebulas in the dwarf satellite galaxy, which is located approximately 200,000 light-years away in the southern constellation Tucana. The image is part of a study called Small Magellanic Cloud Investigation of Dust and Gas Evolution (SMIDGE). Astronomers are using Hubble to probe the Milky Way satellite to understand how dust is different in galaxies that have a far lower supply of heavy elements needed to create dust. The Small Magellanic Cloud has between a fifth and a tenth of the amount of heavy elements that the Milky Way does. Because it is so close, astronomers can study its dust in great detail, and learn about what dust was like earlier in the history of the universe. “It is important for understanding the history of our own galaxy, too,” explained the study’s principal investigator, Dr. Karin Sandstrom of the University of California, San Diego. Most of the star formation happened earlier in the universe, at a time where there was a much lower percentage of heavy elements than there is now. “Dust is a really critical part of how a galaxy works, how it forms stars,” said Sandstrom. Credit: NASA, ESA, STScI, K. Sandstrom (University of California, San Diego), and the SMIDGE team NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments

Social Health Inequalities and eHealth: A Literature Review With Qualitative Synthesis of Theoretical and Empirical Studies.

PubMed

Latulippe, Karine; Hamel, Christine; Giroux, Dominique

2017-04-27

interventions, which are not likely to exacerbate SHI. ©Karine Latulippe, Christine Hamel, Dominique Giroux. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 27.04.2017.

Lunar and Planetary Science XXXV: Asteroids, Meteors, Comets

NASA Technical Reports Server (NTRS)

2004-01-01

Reports included:Long Term Stability of Mars Trojans; Horseshoe Asteroids and Quasi-satellites in Earth-like Orbits; Effect of Roughness on Visible Reflectance Spectra of Planetary Surface; SUBARU Spectroscopy of Asteroid (832) Karin; Determining Time Scale of Space Weathering; Change of Asteroid Reflectance Spectra by Space Weathering: Pulse Laser Irradiation on Meteorite Samples; Reflectance Spectra of CM2 Chondrite Mighei Irradiated with Pulsed Laser and Implications for Low-Albedo Asteroids and Martian Moons; Meteorite Porosities and Densities: A Review of Trends in the Data; Small Craters in the Inner Solar System: Primaries or Secondaries or Both?; Generation of an Ordinary-Chondrite Regolith by Repetitive Impact; Asteroid Modal Mineralogy Using Hapke Mixing Models: Validation with HED Meteorites; Particle Size Effect in X-Ray Fluorescence at a Large Phase Angle: Importance on Elemental Analysis of Asteroid Eros (433); An Investigation into Solar Wind Depletion of Sulfur in Troilite; Photometric Behaviour Dependent on Solar Phase Angle and Physical Characteristics of Binary Near-Earth-Asteroid (65803) 1996 GT; Spectroscopic Observations of Asteroid 4 Vesta from 1.9 to 3.5 micron: Evidence of Hydrated and/or Hydroxylated Minerals; Multi-Wavelength Observations of Asteroid 2100 Ra-Shalom: Visible, Infrared, and Thermal Spectroscopy Results; New Peculiarities of Cometary Outburst Activity; Preliminary Shape Modeling for the Asteroid (25143) Itokawa, AMICA of Hayabusa Mission; Scientific Capability of MINERVA Rover in Hayabusa Asteroid Mission; Characteristics and Current Status of Near Infrared Spectrometer for Hayabusa Mission; Sampling Strategy and Curation Plan of Hayabusa Asteroid Sample Return Mission; Visible/Near-Infrared Spectral Properties of MUSES C Target Asteroid 25143 Itokawa; Calibration of the NEAR XRS Solar Monitor; Modeling Mosaic Degradation of X-Ray Measurements of 433 Eros by NEAR-Shoemaker; Scattered Light Remediation and Recalibration of

External Validation Study of First Trimester Obstetric Prediction Models (Expect Study I): Research Protocol and Population Characteristics.

PubMed

Meertens, Linda Jacqueline Elisabeth; Scheepers, Hubertina Cj; De Vries, Raymond G; Dirksen, Carmen D; Korstjens, Irene; Mulder, Antonius Lm; Nieuwenhuijze, Marianne J; Nijhuis, Jan G; Spaanderman, Marc Ea; Smits, Luc Jm

2017-10-26

. An impact study for the evaluation of the best obstetric prediction models in the Dutch setting with respect to their effect on clinical outcomes, costs, and quality of life-Expect Study II-is being planned. Netherlands Trial Registry (NTR): NTR4143; http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=4143 (Archived by WebCite at http://www.webcitation.org/6t8ijtpd9). ©Linda Jacqueline Elisabeth Meertens, Hubertina CJ Scheepers, Raymond G De Vries, Carmen D Dirksen, Irene Korstjens, Antonius LM Mulder, Marianne J Nieuwenhuijze, Jan G Nijhuis, Marc EA Spaanderman, Luc JM Smits. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 26.10.2017.

On Hilbert-Huang Transform Based Synthesis of a Signal Contaminated by Radio Frequency Interference or Fringes

NASA Technical Reports Server (NTRS)

Kizhner, Semion; Shiri, Ron S.; Vootukuru, Meg; Coletti, Alessandro

2015-01-01

Norden E. Huang et al. had proposed and published the Hilbert-Huang Transform (HHT) concept correspondently in 1996, 1998. The HHT is a novel method for adaptive spectral analysis of non-linear and non-stationary signals. The HHT comprises two components: - the Huang Empirical Mode Decomposition (EMD), resulting in an adaptive data-derived basis of Intrinsic Mode functions (IMFs), and the Hilbert Spectral Analysis (HSA1) based on the Hilbert Transform for 1-dimension (1D) applied to the EMD IMF's outcome. Although paper describes the HHT concept in great depth, it does not contain all needed methodology to implement the HHT computer code. In 2004, Semion Kizhner and Karin Blank implemented the reference digital HHT real-time data processing system for 1D (HHT-DPS Version 1.4). The case for 2-Dimension (2D) (HHT2) proved to be difficult due to the computational complexity of EMD for 2D (EMD2) and absence of a suitable Hilbert Transform for 2D spectral analysis (HSA2). The real-time EMD2 and HSA2 comprise the real-time HHT2. Kizhner completed the real-time EMD2 and the HSA2 reference digital implementations respectively in 2013 & 2014. Still, the HHT2 outcome synthesis remains an active research area. This paper presents the initial concepts and preliminary results of HHT2-based synthesis and its application to processing of signals contaminated by Radio-Frequency Interference (RFI), as well as optical systems' fringe detection and mitigation at design stage. The Soil Moisture Active Passive (SMAP mission (SMAP) carries a radiometer instrument that measures Earth soil moisture at L1 frequency (1.4 GHz polarimetric - H, V, 3rd and 4th Stokes parameters). There is abundant RFI at L1 and because soil moisture is a strategic parameter, it is important to be able to recover the RFI-contaminated measurement samples (15% of telemetry). State-of-the-art only allows RFI detection and removes RFI-contaminated measurements. The HHT-based analysis and synthesis facilitates

"Wish You Were Here": Examining Characteristics, Outcomes, and Statistical Solutions for Missing Cases in Web-Based Psychotherapeutic Trials.

PubMed

Karin, Eyal; Dear, Blake F; Heller, Gillian Z; Crane, Monique F; Titov, Nickolai

2018-04-19

likelihood and jointly predict lesser clinical improvement. Under such circumstances, individuals with potentially worst off treatment outcomes can become concealed, and failure to adjust for this can lead to substantial clinical measurement bias. Together, this preliminary research suggests that missing cases in Web-based psychotherapeutic interventions may not occur as random events and can be systematically predicted. Critically, at the same time, missing cases may experience outcomes that are distinct and important for a complete understanding of the treatment effect. ©Eyal Karin, Blake F Dear, Gillian Z Heller, Monique F Crane, Nickolai Titov. Originally published in JMIR Mental Health (http://mental.jmir.org), 19.04.2018.

Testing Behavior Change Techniques to Encourage Primary Care Physicians to Access Cancer Screening Audit and Feedback Reports: Protocol for a Factorial Randomized Experiment of Email Content.

PubMed

Vaisson, Gratianne; Witteman, Holly O; Bouck, Zachary; Bravo, Caroline A; Desveaux, Laura; Llovet, Diego; Presseau, Justin; Saragosa, Marianne; Taljaard, Monica; Umar, Shama; Grimshaw, Jeremy M; Tinmouth, Jill; Ivers, Noah M

2018-02-16

how to communicate effectively with primary care providers by email and identify which behavior change techniques tested are most effective at encouraging engagement with an audit and feedback report. ClinicalTrials.gov NCT03124316; https://clinicaltrials.gov/ct2/show/NCT03124316 (Archived by WebCite at http://www.webcitation.org/6w2MqDWGu). ©Gratianne Vaisson, Holly O Witteman, Zachary Bouck, Caroline A Bravo, Laura Desveaux, Diego Llovet, Justin Presseau, Marianne Saragosa, Monica Taljaard, Shama Umar, Jeremy M Grimshaw, Jill Tinmouth, Noah M Ivers. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 16.02.2018.

Obituary: Einar A. Tandberg-Hanssen (1921-2011)

NASA Astrophysics Data System (ADS)

Gary, G.; Emslie, A.; Hathaway, David; Moore, Ronald

2011-12-01

Dr. Einar Andreas Tandberg-Hanssen was born on 6 August 1921, in Bergen, Norway, and died on July 22, 2011, in Huntsville, AL, USA, due to complications from ALS (Amyotrophic lateral sclerosis, often referred to as Lou Gehrig's disease). His parents were administrator Birger Tandberg-Hanssen (1883-1951) and secretary Antonie "Mona" Meier (1895-1967). He married Erna Rönning (27 October 1921 - 22 November 1994), a nurse, on 22 June 1951. She was the daughter of Captain Einar Rönning (1890-1969) and Borghild Lyshaug (1897-1980). Einar and Erna had two daughters, Else Biesman (and husband Allen of Rapid City, SD, USA) and Karin Brock (and husband Mike of Gulf Shores, AL, USA). At the time of his death Einar had eight grandchildren and eight great-grandchildren. Dr. Tandberg-Hanssen was an internationally-known member of the solar physics community, with over a hundred published scientific papers and several books, including Solar Activity (1967), Solar Prominences (1974), The Physics of Solar Flares (1988) and The Nature of Solar Prominences (1995). Einar grew up in Langesund and Skien, Norway, where he took the qualifying exams at Skien High School in 1941. After the war he studied natural sciences at the University of Oslo and received his undergraduate degree in astronomy in 1950. He worked as a research assistant in the Institute of Theoretical Astrophysics at the University of Oslo for three intervals in the 1950s, interspersed by fellowships at the Institut d'Astrophysique in Paris, Caltech in Pasadena, CA, the High Altitude Observatory in Boulder, CO, and the Cavendish Laboratory in the UK (at the invitation of British radio-astronomer Sir Martin Ryle). He earned a doctorate in astrophysics at the University in Oslo in 1960 with a dissertation titled "An Investigation of the Temperature Conditions in Prominences with a Special Study of the Excitation of Helium." From 1959-61, Tandberg-Hanssen was a professor at the University in Oslo. He then traveled back to

Adherence to Report and Patient Perception of an Interactive App for Managing Symptoms During Radiotherapy for Prostate Cancer: Descriptive Study of Logged and Interview Data.

PubMed

Langius-Eklöf, Ann; Christiansen, Mats; Lindström, Veronica; Blomberg, Karin; Hälleberg Nyman, Maria; Wengström, Yvonne; Sundberg, Kay

2017-10-31

a sense of security. Few technological problems were reported. The use of Interaktor increased patients' sense of security and their reflections on their own well-being and thereby served as a supportive tool for the self-management of symptoms during treatment of prostate cancer. Some further development of the app's content might be beneficial for future use. ©Ann Langius-Eklöf, Mats Christiansen, Veronica Lindström, Karin Blomberg, Maria Hälleberg Nyman, Yvonne Wengström, Kay Sundberg. Originally published in JMIR Cancer (http://cancer.jmir.org), 31.10.2017.

Universal Versus Conditional Third Day Follow-Up Visit for Children With Nonsevere Unclassified Fever at the Community Level in Ethiopia: Protocol for a Cluster Randomized Noninferiority Trial.

PubMed

Källander, Karin; Alfven, Tobias; Workineh, Ayalkibet Abebe; Hailemariam, Abreham; Petzold, Max; Getachew, Dawit; Barat, Lawrence; Steinhardt, Laura C; Gutman, Julie R

2018-04-12

persistent fever, using a cluster randomized controlled trial design embedded in a national program. Outcomes will be relevant for policy makers and are important for the evaluation of current and future World Health Organization guidelines for the management of children with fever. ClinicalTrials.gov NCT02926625; https://clinicaltrials.gov/ct2/show/NCT02926625 (Archived by WebCite at http://www.webcitation.org/6xrQWn50t). ©Karin Källander, Tobias Alfven, Ayalkibet Abebe Workineh, Abreham Hailemariam,, Max Petzold, Dawit Getachew, Lawrence Barat, Laura C Steinhardt, Julie R Gutman. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 12.04.2018.

Biological soil crusts in Chile along the precipitation gradient

NASA Astrophysics Data System (ADS)

Samolov, Elena; Glaser, Karin; Baumann, Karen; Leinweber, Peter; Jung, Patrick; Büdel, Burkhard; Mikhailyuk, Tatiana; Karsten, Ulf

2017-04-01

Biological soil crusts in Chile along a precipitation gradient Elena Samolov* (1), Karin Glaser (1), Karen Baumann (2), Peter Leinweber (2), Patrick Jung (3), Burkhard Büdel (3), Tatiana Mikhailyuk (4) and Ulf Karsten (1) (1) Institute of Biological Sciences - Applied Ecology and Phycology, University of Rostock, Rostock, Germany, (2) Faculty of Agricultural and Environmental Sciences - Soil Sciences, University of Rostock, Rostock, Germany (3) University of Kaiserslautern, Kaiserslautern, Germany (4) M.H. Kholodny Institute of Botany, National Academy of Science of Ukraine, Kyiv, Ukraine * elena.samolov@uni-rostock.de Biological soil crusts (BSCs) are an association of different microorganisms and soil particles in the top millimeters of the soil. They are formed by algae, cyanobacteria, microfungi, bacteria, bryophytes and lichens in various compositions; together with their by-products they create a micro-ecosystem that performs important ecological functions, e.g. primary production, nitrogen fixation, mineralization and stabilization of soils. These top-soil assemblages are almost unstudied in South America (Büdel et al. 2016). Therefore, our aim is to investigate for the first time biodiversity of the key photosynthetic organisms, green algae and cyanobacteria following a precipitation gradient along the west coast of Chile. We are applying polyphasic approach - a combination of microscopy, culture dependent (16S and 18S rRNA, ITS) and culture independent molecular techniques (NGS). First results, based on culturing and light microscopy, showed high diversity of eukaryotic algae in biocrusts from humid regions, followed by semi-arid regions. Lichen dominated biocrusts from arid regions were characterized by a high diversity of green algae, while cyanobacteria were scarcely present. The functional role of the BSCs in the biogeochemical cycle of phosphorous (P) was evaluated using state of the art analytical methods including 31P-NMR (nuclear magnetic

Using Patient Flow Information to Determine Risk of Hospital Presentation: Protocol for a Proof-of-Concept Study.

PubMed

Pearce, Christopher M; McLeod, Adam; Patrick, Jon; Boyle, Douglas; Shearer, Marianne; Eustace, Paula; Pearce, Mary Catherine

2016-12-20

the combination of variables that will provide the best predictive model. Records of approximately 97,000 patients who have attended both a general practice and an emergency department have been identified within the database. These records are currently being used to develop the predictive model. Records from general practice and emergency department visits have been identified and pooled for development of the algorithm. The next phase in the project will see validation and live testing of the algorithm in a practice setting. The algorithm will underpin a clinical decision support tool for general practitioners which will be tested for face validity in this initial study into its efficacy. ©Christopher M Pearce, Adam McLeod, Jon Patrick, Douglas Boyle, Marianne Shearer, Paula Eustace, Mary Catherine Pearce. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 20.12.2016.

Increasing the Availability of Psychological Treatments: A Multinational Study of a Scalable Method for Training Therapists.

PubMed

O'Connor, Marianne; Morgan, Katy E; Bailey-Straebler, Suzanne; Fairburn, Christopher G; Cooper, Zafra

2018-06-08

.19, 95% CI 0.13-0.25), and those who treated a suitable patient during training had an expected change in competence score 1.2 (95% CI 0.4-2.1) points higher than those who did not. Similarly, there was an association between meeting the competence threshold after training and the number of modules completed (odds ratio, OR=1.11, 95% CI 1.07-1.15), and treating at least one patient during training was associated with competence after training (OR=2.2, 95% CI 1.2-4.1). Independent Web-centered training can successfully train large numbers of therapists dispersed across a wide geographical area. This finding is of importance because the availability of a highly scalable method of training potentially increases the number of people who might receive effective psychological treatments. ©Marianne O'Connor, Katy E Morgan, Suzanne Bailey-Straebler, Christopher G Fairburn, Zafra Cooper. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 08.06.2018.

Assessing Therapist Competence: Development of a Performance-Based Measure and Its Comparison With a Web-Based Measure.

PubMed

Cooper, Zafra; Doll, Helen; Bailey-Straebler, Suzanne; Bohn, Kristin; de Vries, Dian; Murphy, Rebecca; O'Connor, Marianne E; Fairburn, Christopher G

2017-10-31

also sensitive to change, with scores being significantly higher after training than before as might be expected (mean difference 0.758, P<.001) even when taking account of repeated data (mean difference 0.667, P<.001). The major shortcoming of the role-play measure was that it required considerable time and resources. This shortcoming is inherent in the method. Given this, of most interest for assessing training outcome, scores on the Web-based measure efficiently predicted therapist competence, as judged by the role-play measure (with the Web-based measure having a positive predictive value of 77% and specificity of 78%). The results of this study suggest that while it was feasible and acceptable to assess performance using the newly developed role-play measure, the highly scalable Web-based measure could be used in certain circumstances as a substitute for the more labor-intensive, and hence, more costly role-play method. ©Zafra Cooper, Helen Doll, Suzanne Bailey-Straebler, Kristin Bohn, Dian de Vries, Rebecca Murphy, Marianne E O'Connor, Christopher G Fairburn. Originally published in JMIR Mental Health (http://mental.jmir.org), 31.10.2017.

Experiences of General Practitioners and Practice Support Staff Using a Health and Lifestyle Screening App in Primary Health Care: Implementation Case Study.

PubMed

Webb, Marianne Julie; Wadley, Greg; Sanci, Lena Amanda

2018-04-24

decreased over time, even as usage rose slightly. The majority of young people (73/87, 84%) completed Check Up GP in the waiting room, with less than half (35/80, 44%) having received an SMS from the clinic with a link to the tool. Participating staff valued Check Up GP, particularly its facilitation of youth-friendly practice. However, there was at first a lack of organizational systems and capacity to implement the app and also initially a reliance on researchers to facilitate the process. The implementation of a screening app in the dynamic and time-restricted general practice setting presents a range of technical and administrative challenges. Successful implementation of a screening app is possible but requires adequate time and intensive facilitation. More resources, external to staff, are needed to drive and support sustainable technology innovation and implementation in general practice settings. ©Marianne Julie Webb, Greg Wadley, Lena Amanda Sanci. Originally published in JMIR Mhealth and Uhealth (http://mhealth.jmir.org), 24.04.2018.

The benefits and harms of intravenous thrombolysis with recombinant tissue plasminogen activator within 6 h of acute ischaemic stroke (the third international stroke trial [IST-3]): a randomised controlled trial.

PubMed

Sandercock, Peter; Wardlaw, Joanna M; Lindley, Richard I; Dennis, Martin; Cohen, Geoff; Murray, Gordon; Innes, Karen; Venables, Graham; Czlonkowska, Anna; Kobayashi, Adam; Ricci, Stefano; Murray, Veronica; Berge, Eivind; Slot, Karsten Bruins; Hankey, Graeme J; Correia, Manuel; Peeters, Andre; Matz, Karl; Lyrer, Phillippe; Gubitz, Gord; Phillips, Stephen J; Arauz, Antonio

2012-06-23

improved functional outcome. Benefit did not seem to be diminished in elderly patients. UK Medical Research Council, Health Foundation UK, Stroke Association UK, Research Council of Norway, Arbetsmarknadens Partners Forsakringsbolag (AFA) Insurances Sweden, Swedish Heart Lung Fund, The Foundation of Marianne and Marcus Wallenberg, Polish Ministry of Science and Education, the Australian Heart Foundation, Australian National Health and Medical Research Council (NHMRC), Swiss National Research Foundation, Swiss Heart Foundation, Assessorato alla Sanita, Regione dell'Umbria, Italy, and Danube University. Copyright © 2012 Elsevier Ltd. All rights reserved.

The Epital Care Model: A New Person-Centered Model of Technology-Enabled Integrated Care for People With Long Term Conditions.

PubMed

Phanareth, Klaus; Vingtoft, Søren; Christensen, Anders Skovbo; Nielsen, Jakob Sylvest; Svenstrup, Jørgen; Berntsen, Gro Karine Rosvold; Newman, Stanton Peter; Kayser, Lars

2017-01-16

and offered two additional services: an outgoing acute medical team and a local subacute bed function. Based on the findings from the iterative process, and evolving technology and workflow solutions, we propose a robust and feasible model that can provide a framework for developing solutions to support an active life with one or more LTCs. The resulting Epital Care Model (ECM) consists of six stages, and serves as a template for how a digitally-enhanced health service can be provided based on patients' medical needs. The model is designed to be a proactive, preventive, and monitoring health care system that involves individuals in the management of their own health conditions. The ECM is in accordance with WHO's framework for integrated people-centered health services, and may serve as a framework for the development of new technologies and provide a template for future reorganization. ©Klaus Phanareth, Søren Vingtoft, Anders Skovbo Christensen, Jakob Sylvest Nielsen, Jørgen Svenstrup, Gro Karine Rosvold Berntsen, Stanton Peter Newman, Lars Kayser. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 16.01.2017.

A Mobile App to Improve Self-Management of Individuals With Type 2 Diabetes: Qualitative Realist Evaluation.

PubMed

Desveaux, Laura; Shaw, James; Saragosa, Marianne; Soobiah, Charlene; Marani, Husayn; Hensel, Jennifer; Agarwal, Payal; Onabajo, Nike; Bhatia, R Sacha; Jeffs, Lianne

2018-03-16

improvements in HbA 1c over the intervention period. Individuals with moderate baseline self-efficacy and no competing priorities, who identified gaps in understanding of how their actions influence their health, were slow to adopt use but recorded the greatest improvements in HbA 1c . The final group had low baseline self-efficacy and identified a range of psychosocial issues and competing priorities. These participants were uncertain of the benefits of using a Web-based solution to support self-management, ultimately resulting in minimal engagement and no improvement in HbA 1c . Self-efficacy, competing priorities, previous behavior change, and beliefs about Web-based solutions interact to determine engagement and impact on the clinical outcomes. Considering the balance of these patient characteristics is likely to help health care providers identify individuals who are apt to benefit from a Web-based solution to support self-management of T2DM. Web-based solutions could be modified to incorporate the existing screening measures to identify individuals who are at risk of suboptimal adherence to inform the provision of additional support(s) as needed. ©Laura Desveaux, James Shaw, Marianne Saragosa, Charlene Soobiah, Husayn Marani, Jennifer Hensel, Payal Agarwal, Nike Onabajo, R Sacha Bhatia, Lianne Jeffs. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 16.03.2018.

Implementing an Internet-Delivered Skin Cancer Genetic Testing Intervention to Improve Sun Protection Behavior in a Diverse Population: Protocol for a Randomized Controlled Trial.

PubMed

Hay, Jennifer L; Berwick, Marianne; Zielaskowski, Kate; White, Kirsten Am; Rodríguez, Vivian M; Robers, Erika; Guest, Dolores D; Sussman, Andrew; Talamantes, Yvonne; Schwartz, Matthew R; Greb, Jennie; Bigney, Jessica; Kaphingst, Kimberly A; Hunley, Keith; Buller, David B

2017-04-25

average-risk personalized genomic testing for melanoma risk findings, and examine predictors of sun protection at 3 months as the outcome. These findings will be used to develop messages for groups that receive average-risk feedback. Aim 2 will compare rates of test consideration in Hispanics versus non-Hispanics, including consideration of testing pros and cons and registration of a decision to either accept or decline testing. Aim 3 will examine personalized genomic testing for melanoma risk feedback comprehension, recall, satisfaction, and cancer-related distress in those who undergo testing, and whether these outcomes differ by ethnicity (Hispanic vs non-Hispanic), or sociocultural or demographic factors. Final outcome data collection is anticipated to be complete by October 2017, at which point data analysis will commence. This study has important implications for personalized genomics in the context of melanoma risk, and may be broadly applicable as a model for delivery of personalized genomic feedback for other health conditions. ©Jennifer L Hay, Marianne Berwick, Kate Zielaskowski, Kirsten AM White, Vivian M Rodríguez, Erika Robers, Dolores D Guest, Andrew Sussman, Yvonne Talamantes, Matthew R Schwartz, Jennie Greb, Jessica Bigney, Kimberly A Kaphingst, Keith Hunley, David B Buller. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 25.04.2017.

Internet-Delivered Cognitive Behavioral Therapy for Children With Pain-Related Functional Gastrointestinal Disorders: Feasibility Study.

PubMed

Lalouni, Maria; Ljótsson, Brjánn; Bonnert, Marianne; Hedman-Lagerlöf, Erik; Högström, Jens; Serlachius, Eva; Olén, Ola

2017-08-10

parent reported that the symptoms had worsened. We observed a large within-group effect size on the primary outcome measure, child-rated gastrointestinal symptoms from pretreatment to posttreatment (Cohen d=1.14, P<.001, 95% CI 0.69-1.61), and this effect size was maintained at 6-month follow-up (Cohen d=1.40, P<.001, 95% CI 1.04-1.81). We also observed significant improvements from pretreatment to posttreatment on a wide range of child- and parent-rated measures including quality of life, pain intensity, anxiety, depression, and school absence. All results remained stable or were further improved at 6-month follow-up. This study shows that children with longstanding P-FGIDs, and their parents, perceive exposure-based Internet-CBT as a helpful and feasible treatment. The included children improved significantly despite a long duration of abdominal symptoms before the intervention. The treatment shows potential to be highly effective for P-FGIDs. The results need to be confirmed in a randomized controlled trial (RCT). ©Maria Lalouni, Brjánn Ljótsson, Marianne Bonnert, Erik Hedman-Lagerlöf, Jens Högström, Eva Serlachius, Ola Olén. Originally published in JMIR Mental Health (http://mental.jmir.org), 10.08.2017.

NASA Announces 2009 Astronomy and Astrophysics Fellows

NASA Astrophysics Data System (ADS)

2009-02-01

WASHINGTON -- NASA has selected fellows in three areas of astronomy and astrophysics for its Einstein, Hubble, and Sagan Fellowships. The recipients of this year's post-doctoral fellowships will conduct independent research at institutions around the country. "The new fellows are among the best and brightest young astronomers in the world," said Jon Morse, director of the Astrophysics Division in NASA's Science Mission Directorate in Washington. "They already have contributed significantly to studies of how the universe works, the origin of our cosmos and whether we are alone in the cosmos. The fellowships will serve as a springboard for scientific leadership in the years to come, and as an inspiration for the next generation of students and early career researchers." Each fellowship provides support to the awardees for three years. The fellows may pursue their research at any host university or research center of their choosing in the United States. The new fellows will begin their programs in the fall of 2009. "I cannot tell you how much I am looking forward to spending the next few years conducting research in the U.S., thanks to the fellowships," said Karin Oberg, a graduate student in Leiden, The Netherlands. Oberg will study the evolution of water and ices during star formation when she starts her fellowship at the Smithsonian Astrophysical Observatory in Cambridge, Mass. People Who Read This Also Read... Milky Way's Super-efficient Particle Accelerators Caught in The Act Cosmic Heavyweights in Free-for-all Galaxies Coming of Age in Cosmic Blobs Cassiopeia A Comes Alive Across Time and Space A diverse group of 32 young scientists will work on a wide variety of projects, such as understanding supernova hydrodynamics, radio transients, neutron stars, galaxy clusters and the intercluster medium, supermassive black holes, their mergers and the associated gravitational waves, dark energy, dark matter and the reionization process. Other research topics include

Young People, Adult Worries: Randomized Controlled Trial and Feasibility Study of the Internet-Based Self-Support Method "Feel the ViBe" for Adolescents and Young Adults Exposed to Family Violence.

PubMed

van Rosmalen-Nooijens, Karin; Lo Fo Wong, Sylvie; Prins, Judith; Lagro-Janssen, Toine

2017-06-12

. UNIANOVA showed no significant differences. Pre-post paired sample t tests showed significant improvements after 12 weeks for the SCL-90 DEP (P=.03) and ANX (P=.046) subscales. Reported mean Web-based time per week was 2.83 with a session time of 36 min. FtV was rated a mean 7.47 (1-10 Likert scale) with a helpfulness score of 3.16 (1-5 Likert scale). All participants felt safe. Two-thirds of the intervention participants started regular health care. No changes on the IES were found. SCL-90 DEP and ANX showed promising results; however, the calculated sample size was not reached (n=18). FtV functions best as a first step for adolescents and young adults in an early stage of change. FtV can be easily implemented without extensive resources and fits best in the field of public health care or national governmental care. Netherlands National Trial Register (NTR): NTR3692; http://www.trialregister.nl/trialreg/admin/ rctview.asp?TC=3692 (Archived by WebCite at http://www.webcitation.org/6qIeKyjA4). ©Karin van Rosmalen-Nooijens, Sylvie Lo Fo Wong, Judith Prins, Toine Lagro-Janssen. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 12.06.2017.

Reach and Acceptability of a Mobile Reminder Strategy and Facebook Group Intervention for Weight Management in Less Advantaged Adolescents: Insights From the PRALIMAP-INÈS Trial.

PubMed

Saez, Laura; Langlois, Johanne; Legrand, Karine; Quinet, Marie-Hélène; Lecomte, Edith; Omorou, Abdou Y; Briançon, Serge

2018-05-18

-of-year face-to-face interviews, 78.1% (153/196) declared an interest in the Facebook challenge group, which implies having a Facebook account or being able to have access to one. However, only 21 adolescents went through the process of joining the group. Although there was satisfaction with the Facebook group among the participants, the low participation rate in the Facebook group does not allow conclusions to be drawn with confidence. The results are in line with the claim that using information and communication technologies in health programs is unlikely to widen health inequalities. However, in this population of French adolescents, mobile phone strategies seem more adapted to a high school context, and caution should be exercised with a younger audience. Although there is positive appreciation of the SMS attendance-reminders and a Facebook intervention is initially highly appealing to less advantaged adolescents, no evidence of impact could be demonstrated. These results highlight the difficulty in assessing the impact of specific interventions in complex health programs. Clinicaltrials.gov NCT01688453; https://clinicaltrials.gov/ct2/show/NCT01688453 (Archived by WebCite at http://www.webcitation.org/6yy6EQ0SM). ©Laura Saez, Johanne Langlois, Karine Legrand, Marie-Hélène Quinet, Edith Lecomte, Abdou Y Omorou, Serge Briançon, PRALIMAP-INÈS Trial Group. Originally published in JMIR Mhealth and Uhealth (http://mhealth.jmir.org), 18.05.2018.

The Hawaii trails project: comet-hunting in the main asteroid belt

NASA Astrophysics Data System (ADS)

Hsieh, H. H.

2009-10-01

Context: The mysterious solar system object 133P/(7968) Elst-Pizarro is dynamically asteroidal, yet displays recurrent comet-like dust emission. Two scenarios were hypothesized to explain this unusual behavior: 1) 133P is a classical comet from the outer solar system that has evolved onto a main-belt orbit or 2) 133P is a dynamically ordinary main-belt asteroid on which subsurface ice has recently been exposed. If 1) is correct, the expected rarity of a dynamical transition onto an asteroidal orbit implies that 133P could be alone in the main belt. In contrast, if 2) is correct, other icy main-belt objects should exist and could also exhibit cometary activity. Aims: Believing 133P to be a dynamically ordinary, yet icy main-belt asteroid, I set out to test the primary prediction of the hypothesis: that 133P-like objects should be common and could be found by an appropriately designed observational survey. Methods: I conducted just such a survey - the Hawaii Trails Project - of selected main-belt asteroids in a search for objects displaying cometary activity. Optical observations were made of targets selected from among the Themis, Koronis, and Veritas asteroid families, the Karin asteroid cluster, and low-inclination, kilometer-scale outer-belt asteroids, using the Lulin 1.0 m, small and moderate aperture research telescope system (SMARTS) 1.0 m, University of Hawaii 2.2 m, southern astrophysical research (SOAR) 4.1 m, Gemini North 8.1 m, Subaru 8.2 m, and Keck I 10 m telescopes. Results: I made 657 observations of 599 asteroids, discovering one active object now known as 176P/LINEAR, leading to the identification of the new cometary class of main-belt comets (MBCs). These results suggest that there could be ~100 currently active MBCs among low-inclination, kilometer-scale outer-belt asteroids. Physically and statistically, MBC activity is consistent with initiation by meter-sized impactors. The estimated rate of impacts and sizes of resulting active sites, however

Voluminous low-T granite: fluid present partial melting of the crust?

NASA Astrophysics Data System (ADS)

Hand, Martin; Barovich, Karin; Morrissey, Laura; Bockmann, Kiara; Kelsey, David; Williams, Megan

2017-04-01

Voluminous low-T granite: fluid present partial melting of the crust? Martin Hand(1), Karin Barovich(1), Laura Morrissey(1), Vicki Lau(1), Kiara Bockmann(1), David Kelsey(1), Megan Williams(1) (1) Department of Earth Sciences, University of Adelaide, Adelaide, Australia Two general schools of thought exist for the formation of granites from predominantly crustal sources. One is that large-scale anatexis occurs via fluid-absent partial melting. This essentially thermal argument is based on the reasonable premise that the lower crust is typically fluid depleted, and experimental evidence which indicates that fluid-absent partial melting can produce significant volumes of melt, creating compositionally depleted residua that many believe are recorded by granulite facies terranes. The other school of thought is that large-scale anatexis can occur via fluid-fluxed melting. This essentially compositional-based contention is also supported by experimental evidence which shows that fluid-fluxed melting is efficient, including at temperatures not much above the solidus. However, generating significant volumes of melt at low temperatures requires a large reservoir of fluid. If fluid-fluxed melting is a realistic model, the resultant granites should be comparatively low temperature compared to those derived from predominantly fluid-absent partial melting. Using a voluminous suite of aluminous granites in the Aileron Province in the North Australian Craton together with metasedimentary granulites as models for source behaviour, we evaluate fluid-absent verse fluid-present regimes for generating large volumes of crustally-derived melt. The central Aileron Province granites occupy 32,500km2, and in places are in excess of 8 km thick. They are characterised by abundant zircon inheritance that can be matched with metasedimentary successions in the region, suggesting they were derived in large part from melting of crust similar to that presently exposed. A notable feature of many of

PREFACE: EmerQuM 11: Emergent Quantum Mechanics 2011 (Heinz von Foerster Congress)

NASA Astrophysics Data System (ADS)

Grössing, Gerhard

2012-05-01

These proceedings comprise the plenary lectures and poster contributions of the 'Heinz von Foerster Conference 2011' on Emergent Quantum Mechanics (EmerQuM11), which was held at the University of Vienna, 11-13 November 2011. With the 5th International Heinz von Foerster Conference convened at the occasion of von Foerster's 100th birthday, the organizers opted for a twin conference to take place at the Large and Small Ceremonial Halls of the University's main building, respectively. The overall topic was chosen as 'Self-Organization and Emergence', a topic to which von Foerster was an early contributor. While the first conference ('Self-Organization and Emergence in Nature and Society') addressed a more general audience, the second one ('Emergent Quantum Mechanics') was intended as a specialist meeting with a contemporary topic that could both serve as an illustration of von Foerster's intellectual heritage and, more generally, point towards future directions in physics. We thus intended to bring together many of those physicists who are interested in or are working on attempts to understand quantum mechanics as emerging from a suitable classical (or, more generally, deeper level) physics. EmerQuM11 was organized by the Austrian Institute for Nonlinear Studies (AINS), with essential support from the Wiener Institute for Social Science Documentation and Methodology (WISDOM), the Department of Contemporary History at the University of Vienna, and the Heinz von Foerster-Gesellschaft. There were a number of individuals who contributed to the smooth course of our meeting and whom I would like to sincerely thank: Christian Bischof, Thomas Elze, Marianne Ertl, Gertrud Hafner, Werner Korn, Angelika Krawanja, Florian Krug and his team, Sonja Lang, Albert Müller, Ilse Müller, Irene Müller, Karl Müller, Armin Reautschnig, Marion Schirrmacher, Anton Staudinger, Roman Zlabinger, and, last but not least, my AINS colleagues Siegfried Fussy, Herbert Schwabl and Johannes Mesa

List of Participants

NASA Astrophysics Data System (ADS)

2011-09-01

AbeTakashiUniversity of Tokyotabe@nt.phys.s.u-tokyo.ac.jp AmusiaMironRacah Institute of Physics, Jerusalemamusia@vms.huji.ac.il BaldoMarcelloINFN Cataniabaldo@ct.infn.it BansalManiePanjab University, Chandigarhbansalmanni@gmail.com BarrancoFranciscoUniversity of Sevillebarranco@us.es BertschGeorgeUniversity of Washington, Seattlebertsch@u.washington.edu BhagwatAmeeyaCBS Mumbaiameeya@kth.se BorderieBernardIPN Orsayborderie@ipno.in2p3.fr CarbonellJaumeLPSC Grenoblejaume.carbonell@lpsc.in2p3.fr CarlsonJoeLos Alamos National Laboratorycarlson@lanl.gov ColòGianlucaINFN - Università degli Studi di Milanocolo@mi.infn.it DanielewiczPawelNSCL, Michigan State Universitydanielewicz@nscl.msu.edu DescouvemontPierreUniversité Libre de Bruxellespdesc@ulb.ac.be Dohet-EralyJérémyUniversité Libre de Bruxellesjdoheter@ulb.ac.be DraayerJerryLouisiana State Universitydraayer@lsu.edu DufourMarianneIPHC, Université de Strasbourgmarianne.dufour@ires.in2p3.fr DuguetThomasCEA Saclaythomas.duguet@cea.fr DukelskyJorgeCSIC Madriddukelsky@iem.cfmac.csic.es EbranJean-PaulCEA-DAM, Arpajonebran@ipno.in2p3.fr FreerMartinUniversity of Birminghamm.freer@bham.ac.uk FujiiShinichiroUniversity of Tokyosfujii@cns.s.u-tokyo.ac.jp FunakiYasuroRIKEN Nishina Center, Wakofunaki@riken.jp GrassoMarcellaIPN Orsaygrasso@ipno.in2p3.fr HaginoKouichiTohoku Universityhagino@nucl.phys.tohoku.ac.jp HansenHubertUniversité Claude Bernard Lyon 1hansen@ipnl.in2p3.fr HolzmannMarkusLPMMC Grenoblemarkus@lptl.jussieu.fr HoriuchiHisashiRCNP, Osaka Universityhoriuchi@rcnp.osaka-u.ac.jp HoriuchiWataruGSI Darmstadtw.horiuchi@gsi.de HupinGuillaumeGANIL, Caenhupin@ganil.fr JinMengHuazhong Normal University, Wuhanjinm@iopp.ccnu.edu.cn KamimuraMasayasuRIKEN Nishina Center, Wakomkamimura@riken.jp Kanada-En'yoYoshikoKyoto Universityyenyo@ruby.scphys.kyoto-u.ac.jp KatoKiyoshiHokkaido University, Sapporokato@nucl.sci.hokudai.ac.jp KawabataTakahiroKyoto Universitykawabata@scphys.kyoto-u.ac.jp KhanEliasIPN Orsaykhan@ipno.in2p3.fr

PREFACE: International Conference on Strongly Correlated Electron Systems (SCES 2011)

NASA Astrophysics Data System (ADS)

Littlewood, P. B.; Lonzarich, G. G.; Saxena, S. S.; Sutherland, M. L.; Sebastian, S. E.; Artacho, E.; Grosche, F. M.; Hadzibabic, Z.

2012-11-01

, Kyushu G. R. Stewart, Gainesville C. Di Castro, Rome R. Osborn, Chicago H. Takagi, Tokyo M. Eremets, Mainz S. Ovchnikov, Krasnoyarsk L. Taillefer, Sherbrooke M. Fiebig, Bonn C. Panagopoulos, Singapore & Heraklion J. D. Thompson, Los Alamos Z. FiskIrvine S. Paschen, Vienna Y. Tokura, Tokyo J. Flouquet, Grenoble C. Pfleiderer, Munich K. Ueda, Tokyo P. Fulde, Dresden P. Phillips, Urbana C. M. Varma, Riverside A. Geim, Manchester D. Pines, Davis T. Vojta, Rolla J.C. Gomez-Sal, Santander T. V. Ramakrishnan, Bangalore N.L. Wang, Beijing A. Kavokin, Southampton A.K. Raychaudhuri, Calcutta T. Xiang, Beijing J. Goodenough, Austin M. Reifers, Kosice L. Yu, Beijing H. Hosono, Tokyo P. Riseborough, Philadelphia F. C. Zhang, Hong Kong S. Julian, Toronto M. L Saboungi, Orleans G. Zwicknagl, Braunschweig Operational Team Anson Cheung (co-ordinator)Hyeong Jin KimPaul Nahai-Williamson Beng Tan (co-ordinator)Jack GillettPeter Logg Cheng Liu (co-ordinator)Jo WensleyPrajakti Kalra Swee K. Goh (co-ordinator)Jonathan SilverRichard Brierley Adam HalskiLara SibleyRobert Hay Edd CavannaLeona HopeSeb Haines Felix NissenLina KlintbergSitikantha Das Gareth ConduitMarianne BauerStephen Rowley Gerie LonzarichMatt BurgessSven Friedemann Greg LeverMuhammad Ahsan ZebYang Zou Hannah PriceNick BristoweYiqian Xu Haruka TaniguchiOleksandr PoplavskyyZhuo Feng

EDITORIAL Proceedings of the XIV International Conference on Small-Angle Scattering, SAS-2009

NASA Astrophysics Data System (ADS)

Ungar, Goran; Heenan, Richard

2010-10-01

particles based on the radial pair distance distribution function. The model takes account of different types of disorder, i.e. of both 1st ('thermal') and 2nd ('paracrystalline') kind, as well as finite size, stacking and orientational disorder. In paper 012014 Salvino Ciccariello works out the 3D correlation function of plane objects, specifically a triangle of a general shape. This paves the way to analysing morphologies that can be approximated by cylinders of different cross-sections. Papers 012051 (Polte et al.) and 012047 (Bras et al.) report the use of SAS in combination with X-ray spectroscopy. Ristic et al. describe a real-time study of crystal nucleation induced by ultrasound (012049), while Marianne Imperor-Clerc et al. present an investigation of lyotropic liquid crystals under shear (012052). In the Polymers section Geoff Mitchell describes modelling of SANS data on electrospun fibres (012042), while Cabral et al. describes a study of nanoparticle aggregation in bulk and thin polymer films (012046). Work on phospholipid membranes was reported by Spinozzi et al. and by Onai et al. in papers 012019 and 012018, respectively. The latter deals with the effect of osmotic pressure on model 'lipid rafts', these being considered as having an important role in the function of the mammalian cell membrane. Readers interested in biological systems will find a number of other interesting papers describing the use of either SAXS or SANS in the Biological Systems and Membranes section. A number of descriptions of recent designs of SAXS (synchrotron) and SANS beamlines, as well as detector developments can be found in the section on Beamlines and Instrumentation. Goran Ungar, Editor-in-Chief Richard Heenan, Deputy Editor-in-Chief

a Passage to the Universe

NASA Astrophysics Data System (ADS)

1995-11-01

a concluding Press Conference , during which the outcome of this unique event will be summarized by the participants and the organisers: Monday, November 20, 1995, 15:30 pm, at the ESO Headquarters, Karl-Schwarzschild-Strasse 2, D-85748 Garching, Germany List of National First-Prize Winners Belgium: Mr. Freddy Allemeersch (Teacher), Mr. Pieter De Ceuninck, Mr. Jeroen Staelens (Onze-Lieve-Vrouwecollege, Brugge) Denmark: Mr. Joern C. Olsen, Mr. Henrik Struckmann, Mr. Uffe A. Hansen, Mr. Mogens Winther (Teacher) (Soenderborg Amtsgymnasium) Finland: Mr. Reima Eresmaa, Ms. Laura Elina Nykyri, Ms. Reetamaija Janhonen (Cygnaeues-Lukeo, Jyvaeskylae and Jyvaeskylaen Lyseon Lukeo) France: Mr. Rene Cavaroz (Teacher), Mr. Vincent Hardy, Mr. Antoine Lesuffleur (Lycee Chartier, Bayeux) Germany: Ms. Dorothee Barth, Mr. Walter Czech (Teacher), Mr. Uwe Kranz, Ms. Karin Wieland (Immanuel-Kant-Gymnasium, Leinfelden-Echterdingen, Baden-Wuerttemberg) Greece: Ms. Agni Ioannidi, Ms. Elena Katifori, Mr. Vassilis Samiotis, Mr. Vassillos Tzotzes (Teacher) (Second Varvakelo Experimental Lyceum, Athens) Ireland: Mr. Declan Maccuarta (Teacher), Mr. Colm Mcloughlin (St. Peter's College, Wexford, Co. Wexford) Italy: Mr. Pasquale Ciarletta, Ms. Francesca D'elia, Ms. Ada Fortugna (Teacher), Mr. Alfredo Pudano (Liceo Scientifico `Leonardo da Vinci', Reggio Calabria) The Netherlands: Mr. Alex De Beer, Mr. Klaas Huijbregts, Mr. Ruud Nellen (Norbertuscollege, Rosendaal) Spain: Mr. Aritz Atela Aio, Mr. Julen Sarasola Manich (Teacher), Mr. Jon Huertas Rodriquez (Txorierri Batxilergoko Institua, Derio Bizkaia) Sweden: Mr. Rahman Amanullah, Mr. Kjell L. Bonander (Teacher), Mr. Tomas Oppelstrup, Ms. Christin Wiedemann (Saltsjoebadens Samskola, Saltsjoebaden) United Kingdom: Mr. Michael Ching, Dr. Richard Field (Teacher) (Oundle School, Peterborough) National Committees Further information about the national contests may be obtained from the National Committees: Belgium: Dr. C. Sterken, Vrije Universiteit

Book Review: Beitraege zur Astronomiegeschichte, Band 5 (Acta Historica Astronomiae Vol. 15)

NASA Astrophysics Data System (ADS)

Duerbeck, H. W.; Dick, W. R.; Hamel, J.

2002-12-01

Pisa and the librarian Pozzetti at Bologna, and Karin Reich describes and edits Bessel's book critique of Gauss' Theoria Motus. How many one-time astronomers have to earn their living in other ways, become distracted from astronomical research, and vanish from the horizon of astronomical history? In the ninth paper, Hans-Joachim Ilgauds has traced the life of Georg Koch (1851-1905), who started his career as an astronomer at Leipzig Observatory in 1874. Later Koch worked at Hamburg Observatory, and then became an employee at the statistical office in Kiel, and finally director of the statistical office of the Hamburg revenue service. He was a collaborator for the statistical yearbook of German cities, and also contributed to a book investigating the causes and the impact of the cholera epidemic of 1892 in Hamburg. The last two papers deal with the circumstances of the discovery of the first Near-Earth asteroid (433) Eros. It was recorded on photographic plates taken at the Urania-Sternwarte Berlin and at Nice Observatory. The Berlin observer Witt announced the discovery, and only later, the Nice observer Charlois published a position of Eros. While all plates have disappeared, the authors Hans Scholl and Lutz D. Schmadel could prove that the Nice plate was poorly guided and Charlois would have been unable to discover the object. From a copy of the Berlin plate, published 50 years after the discovery by Witt's co-observer F. Linke, the exact position was determined, and the time of observation (which had not been published) was derived. The second article, by Lutz D. Schmadel, deals with the life of the Eros co-discoverer Felix Linke (1879-1959), who later worked in statistic offices, was a frequent writer of popular scientific articles, and later the editor of a journal, "Technik im Hotel'', and author of a book of the same title. As can be seen from the summaries given above, this collection of essays deals mainly with historical events that occurred in Germany and

Congratulations to Carey King

NASA Astrophysics Data System (ADS)

Hall, Charles A. S.

2012-03-01

importance of these more comprehensive EROIs but we do understand that our usual methods of including only energy used directly (e.g. to run a pump) or indirectly (e.g. to manufacture the steel forms used) greatly underestimates the total amount of energy needed to produce energy. In conclusion, Carey King appears to be one of the real rising energy stars as energy becomes again much more important. He is very bright, original and is a very hard worker. I look forward to much exciting, innovative and important work from his endeavors. References Barnett H and Morse C 1963 Scarcity and Growth: The Economics of Natural Resource Availability (Baltimore, MD: Johns Hopkins Press) Cleveland C J, Costanza R, Hall C A S and Kaufmann R 1984 Energy and the United States economy: a biophysical perspective Science 225 890-7 Denison E F 1989 Estimates of Productivity Change by Industry, an Evaluation and an Alternative (Washington, DC: The Brookings Institution) Hall C A S 1972 Migration and metabolism in a temperate stream ecosystem Ecology 53 585-604 Hall C A S and Cleveland C J 1981 Petroleum drilling and production in the United States: yield per effort and net energy analysis Science 211 576-9 Hall C A S and Klitgaard K 2011 Energy and the Wealth of Nations: Understanding the Biophysical Economy (New York: Springer) Kaufmann R 2004 The mechanisms for autonomous energy efficiency increases: a cointegration analysis of the US Energy/GDP Ratio The Energy Journal 25 63-86 King C W 2010 Energy intensity ratios as net energy measures of United States energy production and expenditures Environ. Res. Lett. 5 044006 Murphy D J and Hall C A S 2011 Energy return on investment, peak oil, and the end of economic growth in 'Ecological Economics Reviews' ed Robert Costanza, Karin Limburg and Ida Kubiszewski Ann. N.Y. Acad. Sci. 1219 52-72 Solow R M 1974 The economics of resources or the resources of economics American Economic Review 66 1-14 Odum H T 1973 Environment, Power and Society (New York

EDITORIAL: Focus on Iron-Based Superconductors FOCUS ON IRON-BASED SUPERCONDUCTORS

NASA Astrophysics Data System (ADS)

Hosono, Hideo; Ren, Zhi-An

2009-02-01

Elastic theory for the vortex-lattice melting in iron-based high-Tc superconductors Q-H Chen, Q-M Nie, J-P Lv and T-C Au Yeung Electronic properties of LaO1-xFxFeAs in the normal state probed by NMR/NQR H-J Grafe, G Lang, F Hammerath, D Paar, K Manthey, K Koch, H Rosner, N J Curro, G Behr, J Werner, N Leps, R Klingeler, H-H Klauss, F J Litterst and B Büchner AFe2As2 (A = Ca, Sr, Ba, Eu) and SrFe2-xTMxAs2 (TM = Mn, Co, Ni): crystal structure, charge doping, magnetism and superconductivity Deepa Kasinathan, Alim Ormeci, Katrin Koch, Ulrich Burkhardt, Walter Schnelle, Andreas Leithe-Jasper and Helge Rosner Impurity states in a family of antiferromagnetic iron arsenides Qiang Han and Z D Wang Coherence-incoherence crossover in the normal state of iron oxypnictides and importance of Hund's rule coupling K Haule and G Kotliar Electronic structure of heavily electron-doped BaFe1.7Co0.3As2 studied by angle-resolved photoemission Y Sekiba, T Sato, K Nakayama, K Terashima, P Richard, J H Bowen, H Ding, Y-M Xu, L J Li, G H Cao, Z-A Xu and T Takahashi Absorption and photoemission spectroscopy of rare-earth oxypnictides T Kroll, F Roth, A Koitzsch, R Kraus, D R Batchelor, J Werner, G Behr, B Büchner and M Knupfer Superconductivity in LnFePO (Ln = La, Pr and Nd) single crystals R E Baumbach, J J Hamlin, L Shu, D A Zocco, N M Crisosto and M B Maple Unconventional pairing originating from disconnected Fermi surfaces in the iron-based superconductor Kazuhiko Kuroki, Seiichiro Onari, Ryotaro Arita, Hidetomo Usui, Yukio Tanaka, Hiroshi Kontani and Hideo Aoki Near-degeneracy of several pairing channels in multiorbital models for the Fe pnictides S Graser, T A Maier, P J Hirschfeld and D J Scalapino Investigation of superconducting gap structure in TbFeAsO0.9F0.1 using point contact Andreev reflection K A Yates, K Morrison, J A Rodgers, G B S Penny, J-W G Bos, J P Attfield and L F Cohen Competition of magnetism and superconductivity in underdoped (Ba1-xKx)Fe2As2 Marianne Rotter, Marcus

The Most Remote Gamma-Ray Burst

NASA Astrophysics Data System (ADS)

2000-10-01

, Denmark), Johan Fynbo, Palle Møller (European Southern Observatory), Richard Marc Kippen (University of Alabama in Huntsville and NASA/Marshall Space Flight Center, USA), Bjarne Thomsen (University of Århus, Denmark), Marianne Vestergaard (Ohio State University, USA), Nicola Masetti, Eliana Palazzi (Instituto Tecnologie e Studio Radiazoni Extraterresti, Bologna, Italy) Kevin Hurley (University of California, Berkeley, USA), Thomas Cline (NASA Goddard Space Flight Center, Greenbelt, USA), Lex Kaper (Sterrenkundig Instituut ``Anton Pannekoek", the Netherlands) and Andreas O. Jaunsen (formerly University of Oslo, Norway; now ESO-Paranal). [2]: Detailed reports about the early observations of this gamma-ray burst are available at the dedicated webpage within the GRB Coordinates Network website. [3]: The photometric redshift method makes it possible to judge the distance to a remote celestial object (a galaxy, a quasar, a gamma-ray burst afterglow) from its measured colours. It is based on the proportionality between the distance and the velocity along the line of sight (Hubble's law) that reflects the expansion of the Universe. The larger the distance of an object is, the larger is its velocity and, due to the Doppler effect, the spectral shift of its emission towards longer (redder) wavelengths. Thus, the measured colour provides a rough indication of the distance. Examples of this method are shown in ESO PR 20/98 (Photos 48a/00 and 48e/00). [4]: In fact, the object was so faint that the positioning of the spectrograph slit had to be done in "blind" offset, i.e. without actually seeing the object on the slit during the observation. This very difficult observational feat was possible because of excellent preparations by the team of astronomers and the very good precision of the telescope and instrument. [5]: The " Lyman-alpha forest" refers to the crowding of absorption lines from intervening hydrogen clouds, shortward of the strong Lyman-alpha spectral line at rest

Young Astronomers' Observe with ESO Telescopes

NASA Astrophysics Data System (ADS)

1995-11-01

project concerned the actual construction of a working solar radio interferometer, a rather complex instrument that allows measurements of the long-wavelength radiation from the Sun and to map the locations in the solar corona where this radiation originates. The antennae and receiver were designed for frequences around 550 and 750 MHz and were built by the team members themselves. Radio signals from the Sun (as interference fringes) were effectively observed with this instrument, documenting the excellent functioning of this advanced equipment. Germany: Ms. Dorothee Barth, Mr. Walter Czech (Teacher), Mr. Uwe Kranz, Ms. Karin Wieland (Immanuel-Kant-Gymnasium, Leinfelden-Echterdingen, Baden-Wurttemberg) Following a careful planning phase, systematic observations of the 14-magnitude planet Pluto were made with a CCD camera and a 30-cm telescope during 18 nights in the spring and summer of this year. Five nearby stars were used to calibrate the resulting photometric measurements. In the end, this programme was shown to achieve a very good photometric accuracy of about +- 0.2 magnitude per measurement. The variation of Pluto's brightness was found to be about 0.7 magnitude for this particular instrumental combination (no filtre). It was thus possible to draw the lightcurve which was found to be in complete agreement with the established 6.4 day rotation period. Greece: Ms. Agni Ioannidi, Ms. Elena Katifori, Mr. Vassilis Samiotis, Mr. Vassillos Tzotzes (Teacher) (Varvakio Experimental Lyceum, Athens) The project starts out from a star of 1.56 solar mass and a certain density. From this, its size, luminosity, temperature, pressure and other parameters are calculated. With an analogue to the Titius-Bode law for planetary distances, a new planetary system is constructed. It has 5 planets, 3 of which are of the terrestrial type and the other 2 are giant gas planets, larger than Jupiter. Their physical characteristics are calculated. One planet (the 3rd from the central star) is