Pressure Contact Sounding Data for NASA's Atmospheric Variability Experiment (AVE 3)

NASA Technical Reports Server (NTRS)

Fuelberg, H. E.; Hill, C. K.; Turner, R. E.; Long, K. E.

1975-01-01

The basic rawinsonde data are described at each pressure contact from the surface to sounding termination for the 41 stations participating in the AVE III measurement program that began at 0000 GMT on February 6 and ended at 1200 GMT on February 7, 1975. Soundings were taken at 3-hour intervals during a large period of the experiment from most stations within the United States east of about 105 degrees west longitude. Methods of data processing, change in reduction scheme since the AVE II pilot experiment, and data accuracy are briefly discussed. An example of contact data is presented, and microfiche cards of all the contact data are included in the appendix. The AVE III project was conducted to better understand and establish the extent of applications for meteorological satellite sensor data through correlative ground truth experiments and to provide basic experimental data for use in studies of atmospheric scales of-motion interrelationships.

Independent Peer Review of Communications, Navigation, and Networking re-Configurable Testbed (CoNNeCT) Project Antenna Pointing Subsystem (APS) Integrated Gimbal Assembly (IGA) Structural Analysis

NASA Technical Reports Server (NTRS)

Raju, Ivatury S.; Larsen, Curtis E.; Pellicciotti, Joseph W.

2010-01-01

Glenn Research Center Chief Engineer's Office requested an independent review of the structural analysis and modeling of the Communications, Navigation, and Networking re-Configurable Testbed (CoNNeCT) Project Antenna Pointing Subsystem (APS) Integrated Gimbal Assembly (IGA) to be conducted by the NASA Engineering and Safety Center (NESC). At this time, the IGA had completed its critical design review (CDR). The assessment was to be a peer review of the NEi-NASTRAN1 model of the APS Antenna, and not a peer review of the design and the analysis that had been completed by the GRC team for CDR. Thus, only a limited amount of information was provided on the structural analysis. However, the NESC team had difficulty separating analysis concerns from modeling issues. The team studied the NASTRAN model, but did not fully investigate how the model was used by the CoNNeCT Project and how the Project was interpreting the results. The team's findings, observations, and NESC recommendations are contained in this report.

View of twofamily house at 520522 Rison Ave., NE, originally ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

View of two-family house at 520-522 Rison Ave., NE, originally occupied by workers in nearby mills. Note original asbestos shingle roof - 520-522 Rison Avenue, Northeast (House), Huntsville, Madison County, AL

Studies of vorticity imbalance and stability, moisture budget, atmospheric energetics, and gradients of meteorological parameters during AVE 3

NASA Technical Reports Server (NTRS)

Scoggins, J. R. (Editor)

1978-01-01

Four diagnostic studies of AVE 3. are presented. AVE 3 represents a high wind speed wintertime situation, while most AVE's analyzed previously represented springtime conditions with rather low wind speeds. The general areas of analysis include the examination of budgets of vorticity, moisture, kinetic energy, and potential energy and a synoptic and statistical study of the horizontal gradients of meteorological parameters. Conclusions are integrated with and compared to those obtained in previously analyzed experiments (mostly springtime weather situations) so as to establish a more definitive understanding of the structure and dynamics of the atmosphere under a wide range of synoptic conditions.

1. 133842 PACIFIC AVE. ITALIANATE BUILDING ON LEFT IS THE ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. 1338-42 PACIFIC AVE. ITALIANATE BUILDING ON LEFT IS THE CITIZENS BANK AND THE IRVING BUILDING (1888-89). A HOMOGENEOUS DESIGN FOR THREE SEPERATE PROPERTY OWNERS, DESIGNED BY CARL AUGUST DARMER. - Union Depot Area Study, Tacoma, Pierce County, WA

NASA's participation in the AVE-SESAME '79 program

NASA Technical Reports Server (NTRS)

Hill, K.; Turner, R. E.; Wilson, G. S.

1979-01-01

NASA's Marshall Space Flight Center participated with its AVE (Atmospheric Variability Experiment) in a large interagency mesoscale and severe storms experiment identified herein as AVE-SESAME '79 (Atmospheric Variability Experiment-Severe Environmental Storms and Mesoscale Experiment 1979). A primary objective of NASA was to support an effort to acquire carefully edited sets of rawinsonde data during selected severe weather events for use in correlative and diagnostic studies with satellite and radar data obtained at approximately the same times. Data were acquired during six individual 24-h experiments on both the regional and storm scales over a network in the central United States that utilized approximately 20 supplemental rawinsonde sites meshed among 23 standard National Weather Service sites. Included among the six experiments are data obtained between 1200 GMT on April 10 and 1200 GMT on April 11, encompassing the formation and development period for the tornado-producing systems that devastated Wichita Falls, Texas, and other sections of Oklahoma and Texas. The other dates for which data sets are available are April 19-20 and 25-26, May 9-10 and 20-21, and June 7-8, 1979.

AVE0991, a nonpeptide analogue of Ang-(1-7), attenuates aging-related neuroinflammation.

PubMed

Jiang, Teng; Xue, Liu-Jun; Yang, Yang; Wang, Qing-Guang; Xue, Xiao; Ou, Zhou; Gao, Qing; Shi, Jian-Quan; Wu, Liang; Zhang, Ying-Dong

2018-04-17

During the aging process, chronic neuroinflammation induced by microglia is detrimental for the brain and contributes to the etiology of several aging-related neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease. As a newly identified axis of renin-angiotensin system, ACE2/Ang-(1-7)/MAS1 axis plays a crucial role in modulating inflammatory responses under various pathological conditions. However, its relationship with aging-related neuroinflammation is less studied so far. In this study, by using SAMP8 mice, an animal model of accelerated aging, we revealed that the neuroinflammation in the aged brain might be attributed to a decreased level of Ang-(1-7). More importantly, we provided evidence that AVE0991, a nonpeptide analogue of Ang-(1-7), attenuated the aging-related neuroinflammation via suppression of microglial-mediated inflammatory response through a MAS1 receptor-dependent manner. Meanwhile, this protective effect might be ascribed to the M2 activation of microglia induced by AVE0991. Taken together, these findings reveal the association of Ang-(1-7) with the inflammatory response in the aged brain and uncover the potential of its nonpeptide analogue AVE0991 in attenuation of aging-related neuroinflammation.

Comunidades de aves y lepidopteros diurnos y las relaciones entre ellas en bosque nuboso y cafetal de Finca Santa Maura, Jinotega

Treesearch

M. Torrez; W. Arendt; J. M. Maes

2013-01-01

Para evaluar la diversidad de aves y mariposas ninfálidas visitamos la Estación Biológica Juan Roberto Zarruk en Jinotega, donde colectamos datos en todos los hábitats presentes en la finca. Obtuvimos 123 especies de aves y 29 especies de ninfálidos. El hábitat con mayor riqueza para aves fue el cafetal y para ninfálidos el tacotal. Entre las especies más comunes...

Relationships between convective storms and their environment in AVE IV determined from a three-dimensional subsynoptic-scale, trajectory model

NASA Technical Reports Server (NTRS)

Wilson, G. S.

1977-01-01

The paper describes interrelationships between synoptic-scale and convective-scale systems obtained by following individual air parcels as they traveled within the convective storm environment of AVE IV. (NASA's fourth Atmospheric Variability Experiment, AVE IV, was a 36-hour study in April 1975 of the atmospheric variability and structure in regions of convective storms.) A three-dimensional trajectory model was used to calculate parcel paths, and manually digitized radar was employed to locate convective activity of various intensities and to determine those trajectories that traversed the storm environment. Spatial and temporal interrelationships are demonstrated by reference to selected time periods of AVE IV which contain the development and movement of the squall line in which the Neosho tornado was created.

A preliminary look at AVE-SESAME 3 conducted on 25-26 April 1979

NASA Technical Reports Server (NTRS)

Williams, S. F.; Horvath, N.; Turner, R. E.

1980-01-01

General weather conditions, including synoptic maps, radar reports, satellite photographs, precipitation areas and amounts, and a summary of severe weather reports are presented. These data provide researchers a preliminary look at conditions during the AVE-SESAME 3 period.

AVE-Sesame 3: 25-MB sounding data

NASA Technical Reports Server (NTRS)

Williams, S. T.; Gerhard, M. L.; Gilchrist, L. P.; Turner, R. E.

1980-01-01

The rawinsonde sounding program for the AVE-SESAME 3 experiment is described and tabulated data at 25-mb intervals from the surface to 25 mb for the 23 National Weather Service and 19 special stations participating in the experiment are presented. Soundings were taken at 3 hr intervals beginning at 1200 GMT on April 25, 1979, and ending at 1200 GMT on April 26, 1979 (nine sounding times). The method of processing is discussed briefly, estimates of the rms errors in the data presented, an example of contact data given, reasons given for the termination of soundings below 100 mb, and soundings listed which exhibit abnormal characteristics.

AVE-SESAME IV: 25 mb sounding data

NASA Technical Reports Server (NTRS)

Sienkiewicz, M. E.; Gilchrist, L. P.; Turner, R. E.

1980-01-01

The rawinsonde sounding program for the AVE-SESAME 4 experiment is descirbed and tabulated data at 25 mb for the 23 National Weather Service and 20 special stations participating in the experiment are presented. Soundings were taken at 3 hr intervals beginning at 1200 GMT on May 9, 1979, and ending at 1200 GMT on May 10, 1979 (nine sounding times). The method of processing is discussed, estimates of the rms errors in the data are presented, and an example of contact data is given. Reasons are given for the termination of soundings below 100 mb, and soundings are listed which exhibit abnormal characteristics.

A preliminary look at AVE-SESAME 4 conducted on 9-10 May 1979

NASA Technical Reports Server (NTRS)

July, M.; Turner, R. E.

1980-01-01

This report contains information on data collected, symptotic conditions, and severe and unusual weather reported during the Atmospheric Variability Experiment Severe Environmental Storms and Mesoscale Experiment (AVE-SESAME) 4 period. The information provides researchers a look at conditions during the period.

Genetic evidence for the origin and relationships of Hawaiian honeycreepers (Aves: Fringillidae)

Treesearch

Ned K. Johnson; Jill A. Marten; C. John Ralph

1989-01-01

Using starch gel electrophoresis of proteins, we examined variation at 36 genetic loci in nine species (eight genera) of Hawaiian honeycreepers (Class Aves; Family Fringillidae; Subfamily Drepanidinae). Two species of cardueline finches and two emberizids served as outgroup taxa. Twenty-three loci (64%) were either polymorphic within taxa and/or were fixed at...

Data for first NASA Atmospheric Variability Experiment (AVE 1). Part 1: Data tabulation. [rawindsonde data for eastern United States

NASA Technical Reports Server (NTRS)

Scoggins, J. R.; Smith, O. E.

1973-01-01

A tablulation is given of rawinsonde data for NASA's first Atmospheric Variability Experiment (AVE 1) conducted during the period February 19-22, 1964. Methods of data handling and processing, and estimates of error magnitudes are also given. Data taken on the AVE 1 project in 1964 enabled an analysis of a large sector of the eastern United States on a fine resolution time scale. This experiment was run in February 1964, and data were collected as a wave developed in the East Gulf on a frontal system which extended through the eastern part of the United States. The primary objective of AVE 1 was to investigate the variability of parameters in space and over time intervals of three hours, and to integrate the results into NASA programs which require this type of information. The results presented are those from one approach, and represent only a portion of the total research effort that can be accomplished.

TES Carbon Monoxide Validation during the Two AVE Campaigns using the Argus and ALIAS Instruments on NASA's WB-57F

NASA Technical Reports Server (NTRS)

Lopez, Jinena P.; Luo, Ming; Christensen, Lance E.; Loewenstein, Max; Jost, Hansjurg; Webster, Christopher R.; Osterman, Greg

2008-01-01

The Aura Validation Experiment (AVE) focuses on validating Aura satellite measurements of important atmospheric trace gases using ground-based, aircraft, and balloon-borne instruments. Global satellite observations of CO from the Tropospheric Emission Spectrometer (TES) on the EOS Aura satellite have been ongoing since September 2004. This paper discusses CO validation experiments during the Oct-AVE (2004 Houston, Texas) and CR-AVE (2006 San Jose, Costa Rica) campaigns. The coincidences in location and time between the satellite observations and the available in situ profiles for some cases are not ideal. However, the CO distribution patterns in the two validation flight areas are shown to have very little variability in the aircraft and satellite . observations, thereby making them suitable for validation comparisons. TES CO profiles, which typically have a retrieval uncertainty of 10-20%, are compared with in situ CO measurements from NASA Ames Research Center's Argus instrument taken on board the WB-57F aircraft during Oct-AVE. TES CO retrievals during CR-AVE are compared with in situ measurements from Jet Propulsion Laboratory's Aircraft Laser Infrared Absorption Spectrometer (ALIAS) instrument as well as with the Argus instrument, both taken on board the WB-57F aircraft. During CR-AVE, the average overall difference between ALIAS and Argus CO was 4%, with the ALIAS measurement higher. During individual flights, 2-min time-averaged differences between the two in situ instruments had standard deviation of 14%. The TES averaging kernels and a priori constraint profiles for CO are applied to the in situ data for proper comparisons to account for the reduced vertical resolution and the influence of the a priori in the satellite-derived profile. In the TES sensitive pressure range, approx.700-200 hPa, the in situ profiles and TES profiles agree within 5-10%, less than the variability in CO distributions obtained by both TES and the aircraft instruments in the two

A Physics-driven Neural Networks-based Simulation System (PhyNNeSS) for multimodal interactive virtual environments involving nonlinear deformable objects

PubMed Central

De, Suvranu; Deo, Dhannanjay; Sankaranarayanan, Ganesh; Arikatla, Venkata S.

2012-01-01

Background While an update rate of 30 Hz is considered adequate for real time graphics, a much higher update rate of about 1 kHz is necessary for haptics. Physics-based modeling of deformable objects, especially when large nonlinear deformations and complex nonlinear material properties are involved, at these very high rates is one of the most challenging tasks in the development of real time simulation systems. While some specialized solutions exist, there is no general solution for arbitrary nonlinearities. Methods In this work we present PhyNNeSS - a Physics-driven Neural Networks-based Simulation System - to address this long-standing technical challenge. The first step is an off-line pre-computation step in which a database is generated by applying carefully prescribed displacements to each node of the finite element models of the deformable objects. In the next step, the data is condensed into a set of coefficients describing neurons of a Radial Basis Function network (RBFN). During real-time computation, these neural networks are used to reconstruct the deformation fields as well as the interaction forces. Results We present realistic simulation examples from interactive surgical simulation with real time force feedback. As an example, we have developed a deformable human stomach model and a Penrose-drain model used in the Fundamentals of Laparoscopic Surgery (FLS) training tool box. Conclusions A unique computational modeling system has been developed that is capable of simulating the response of nonlinear deformable objects in real time. The method distinguishes itself from previous efforts in that a systematic physics-based pre-computational step allows training of neural networks which may be used in real time simulations. We show, through careful error analysis, that the scheme is scalable, with the accuracy being controlled by the number of neurons used in the simulation. PhyNNeSS has been integrated into SoFMIS (Software Framework for Multimodal

Early quantitative evaluation of a tumor vasculature disruptive agent AVE8062 using dynamic contrast-enhanced ultrasonography.

PubMed

Lavisse, Sonia; Lejeune, Pascale; Rouffiac, Valérie; Elie, Nicolas; Bribes, Estelle; Demers, Brigitte; Vrignaud, Patricia; Bissery, Marie-Christine; Brulé, Aude; Koscielny, Serge; Péronneau, Pierre; Lassau, Nathalie

2008-02-01

To evaluate the early tumor vasculature disrupting effects of the AVE8062 molecule and the feasibility of dynamic contrast-enhanced ultrasonography (DCE-US) in the quantitative assessment of these effects. AVE8062 was administered at a single dose (41 mg/kg) to 40 melanoma-bearing nude mice, which were all imaged before and after drug administration (5 + 15 minutes, 1, 6, and 24 hours). Using an ultrasound scanner (Aplio, Toshiba), intratumor vessels were counted in power Doppler mode and tumor microvasculature was assessed in a specific harmonic mode associated with a perfusion and quantification software for contrast-uptake quantification (Sonovue, Bracco). The peak intensity (PI), time-to-PI (T PI), and full-width at half maximum (FWHM) were extracted from the time-intensity curves expressed as linear raw data. Histologic analysis evaluated microvessel density (MVD) and necrosis at each time point studied. Statistical significance was estimated (paired sum rank and Mann-Whitney tests) to evaluate drug activity and to compare its efficacy at the different time points. In power Doppler mode, intratumoral vessels depletion started 15 minutes postinjection (32%, P = 0.004) and the decrease was maximal at 6 hours (51%, P = 0.002). PI decreased by 3.5- and 45.7-fold at 1 and 6 hours, respectively, compared with preinjection values (P = 0.016 and P = 0.008). The decrease at 6 hours was significantly different from the variation at 1 hour (P = 0.0012) and at 24 hours (P = 0.0008). T PI and FWHM showed a significant increase exclusively at 6 hours (P = 0.0034, P = 0.0039). Histology revealed significantly decreased MVD and increased necrosis at 24 hours (P < 0.01). DCE-US allowed quantitative in vivo evaluation of the functional effects of AVE8062, which was found most effective on tumoral microvasculature 6 hours after its administration. A clinical phase-1 study of AVE8062 is ongoing using the same ultrasonography methodology before and 6 and 24 hours

Population trends and survival of nesting green sea turtles Chelonia mydas on Aves Island, Venezuela

USGS Publications Warehouse

Garcia-Cruz, Marco A.; Lampo, Margarita; Peñaloza, Claudia L.; Kendall, William L.; Solé, Genaro; Rodriguez-Clark, Kathryn M.

2015-01-01

Long-term demographic data are valuable for assessing the effect of anthropogenic impacts on endangered species and evaluating recovery programs. Using a 2-state open robust design model, we analyzed mark-recapture data from green turtles Chelonia mydas sighted between 1979 and 2009 on Aves Island, Venezuela, a rookery heavily impacted by human activities before it was declared a wildlife refuge in 1972. Based on the encounter histories of 7689 nesting females, we estimated the abundance, annual survival, and remigration intervals for this population. Female survival varied from 0.14-0.91, with a mean of 0.79, which is low compared to survival of other populations from the Caribbean (mean = 0.84) and Australia (mean = 0.95), even though we partially corrected for tag loss, which is known to negatively bias survival estimates. This supports prior suggestions that Caribbean populations in general, and the Aves Island population in particular, may be more strongly impacted than populations elsewhere. It is likely that nesters from this rookery are extracted while foraging in remote feeding grounds where hunting still occurs. Despite its relatively low survival, the nesting population at Aves Island increased during the past 30 years from approx. 500 to >1000 nesting females in 2009. Thus, this population, like others in the Caribbean and the Atlantic, seems to be slowly recovering following protective management. Although these findings support the importance of long-term conservation programs aimed at protecting nesting grounds, they also highlight the need to extend management actions to foraging grounds where human activities may still impact green turtle populations.

1. VIEW OF MILL WORKER HOUSE AT 502 ASKEW AVE. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. VIEW OF MILL WORKER HOUSE AT 502 ASKEW AVE. HOUSE IS 1 1/2 STORY, 3 BAY SIDE GABLE WITH REAR KITCHEN ELL AND PORCH EXTENDING FROM FRONT. LOCKWOOD GREENE ENGINEERS BUILT THIS AND 128 OTHER NEW HOUSES FOR NEW ENGLAND SOUTHERN MILLS IN 1923-1924. THE PREEXISTING MILL VILLAGE NEEDED TO BE EXPANDED TO ACCOMODATE WORKERS FOR THEIR NEW STARK MILL IN HOGANSVILLE. THIS HOUSE WAS BUILT WITH INDOOR PLUMBING, AND ELECTRICITY AT A COST OF APPROXIMATELY $430 PER ROOM. - 502 Askew Avenue (House), 502 Askew Avenue, Hogansville, Troup County, GA

Complete mitochondrial genome of Germain's Peacock-Pheasant Polyplectron germaini (Aves, Galliformes, Phasianidae).

PubMed

Omeire, Destiny; Abdin, Shaunte; Brooks, Daniel M; Miranda, Hector C

2015-04-01

The Germain's Peacock-Pheasant Polyplectron germaini (Aves, Galliformes, Phasianidae) is classified as Near Threatened on the IUCN Red List. The complete mitochondrial genome of P. germaini is 16,699 bp, consisting of 13 protein-coding genes, 2 rRNA, 22 tRNA genes and 1 control region. All of the 13 protein-coding genes have ATG as start codon. Eight of the 13 protein-coding genes have TAA as stop codon.

Does Previous Hip Surgery Effect the Outcome of Tönnis Triple Periacetabular Osteotomy? Mid-Term Results.

PubMed

Konya, Mehmet Nuri; Aydn, Bahattin Kerem; Yldrm, Timur; Sofu, Hakan; Gürsu, Sarper

2016-03-01

Hip dysplasia (HD) is 1 of the major reasons of coxarthrosis. The goal of the treatment of HD by Tönnis triple pelvic osteotomy (TPAO) is to improve the function of hip joint while relieving pain, delaying and possibly preventing end-stage arthritis. The aim of this study is to compare the clinical and radiological results of TPAO to determine if previous surgery has a negative effect on TPAO.Patients operated with TPAO between 2005 and 2010, included in this study. Patients divided into 2 groups: primary acetabular dysplasia (PAD) and residual acetabular dysplasia (RAD). Prepostoperatively, hip range of motion, Harris hip score (HHS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) hip score, visual analog scores (VAS), impingement tests, and also the presence of Trendelenburg sign (TS) were investigated for clinical evaluation. For radiological analysis pre-postoperative, anterior-posterior (AP) pelvis and faux profile radiographs were used. Acetabular index, lateral center edge (LCE) angle, and Sharp angles were measured by AP pelvis; anterior center edge (ACE) angle were measured by faux profile radiography. All the clinical and radiological data of the groups were analyzed separately for the pre-postoperative scores also the amount of improvement in all parameters were analyzed.SPSS20 (SPSS Inc., Chicago, IL) was used for statistical analysis. Wilcoxon test, McNemar test, paired t tests, and Mann-Whitney U tests were used to compare the groups. P < 0.05 were defined as statistically significant.Study included 27 patients: 17 patients were in PAD and 10 patients were in RAD. The mean follow-up period was 6.2 years (5.2-10.3 years). In all patients, the radiological and the clinical outcomes were better after TPAO except the flexion of the hip parameter. When the patient groups were evaluated as pre-postoperatively, more statistically significant parameters were found in the PAD group when compared with RAD group. Extension

AVE/VAS 3: 25-mb sounding data

NASA Technical Reports Server (NTRS)

Sienkiewicz, M. E.

1982-01-01

The rawinsonde sounding program for the AVE/VAS 3 experiment is described. Tabulated data are presented at 25-mb intervals for the 24 National Weather Service stations and 14 special stations participating in the experiment. Soundings were taken at 3-hr intervals, beginning at 1200 GMT on March 27, 1982, and ending at 0600 GMT on March 28, 1982 (7 sounding times). An additional sounding was taken at the National Weather Service stations at 1200 GMT on March 28, 1982, at the normal synoptic observation time. The method of processing soundings is briefly discussed, estimates of the RMS errors in the data are presented, and an example of contact data is given. Termination pressures of soundings taken in the mesos-beta-scale network are tabulated, as are observations of ground temperature at a depth of 2 cm.

Asymmetric Grenada Basin and its Relation with Aves Ridge and Lesser Antilles Arc : Preliminary Results from Cruise GARANTI

NASA Astrophysics Data System (ADS)

Lallemand, S.; Lebrun, J. F.

2017-12-01

The Grenada Basin is a crescent-shape basin in a back-arc position relative to the Lesser Antilles arc. About 140 km wide, 3000 m deep and with a flat topography in its southern part, the basin shallows, narrows and becomes rougher northward. Its structural and genetic relations with the N-S-trending, ca.1000 m deep, Aves Ridge to the west, previously interpreted as the ante-Eocene remnant arc and the Lesser Antilles modern volcanic arc are debated. The GARANTI deep-seismic survey across the Grenada Basin (May-June 2017 French R/V L'Atalante), acquired two transverse (E-W) and one longitudinal (N-S), ca. 300 km long, wide-angle seismic lines shot using a 6473 in3 seismic source array, and recorded by 40 ocean bottom seismometers together with ca. 3500 km of 720-traces seismic reflection lines. This data set revealed a clear asymmetry along both N-S and E-W directions. To the North and to the West, the crust beneath the basin is rather thick and non-oceanic, whereas it is probably oceanic to the southeast. We pay special attention to structural relations between the basin itself and the Aves Ridge in one hand and the Antilles Arc in the other hand. The basin is filled by up to 7km of flat-lying sediments, thickening eastward and showing no apparent deformation. The Lesser Antilles arc margin is abrupt and does not appear to be the conjugate of the Aves Ridge margin. Fourteen dredges were collected, half of them were taken along the east flank of the Aves Ridge facing the deep Grenada basin. Evidences of past Cenozoic emersion of the Aves Ridge were found from drowned reef seamounts lying down to 1100 m bsl. Further analyses should better portrait the tectonic evolution of the Lesser Antilles back-arc area. GARANTI Scientific Team : A. Agranier, D. Arcay, F. Audemard, M.-A. Bassetti, M.-O. Beslier, M. Boucard, J.-J. Cornée, M. Fabre, A. Gay, D. Graindorge, A. Heuret, F. Klingelhoefer, M. Laigle, J.-L. Léticée, D. Malengros, B. Marcaillou, B. Mercier de Lépinay, P

Slow NE-SW to NNE-SSW extension in the Pasto Ventura region of the southern Puna Plateau

NASA Astrophysics Data System (ADS)

Zhou, R.; Schoenbohm, L. M.; Cosca, M. A.

2011-12-01

Recent extension on the Puna Plateau of NW Argentina has been linked to lithospheric foundering, gravitational spreading, and edge effects. However, the timing, kinematics and rate of extension are poorly constrained. In the Pasto Ventura region, along the southern margin of the plateau, we map out two different groups of faults: (1) recently formed Quaternary normal faults and strike-slip faults; and (2) pre-Quaternary reverse faults reactivated in the Quaternary. The faults in Group (1) are relatively short (~1-2 km) normal and strike-slip faults that offset Quaternary geomorphic features. The orientation of these faults indicates NE-SW to NNE-SSW extension. The faults in Group (2) bound exposures of basement rock and are associated with basaltic cinder cones and lava flows. Previous studies indicate they were reverse faults which have been reactivated as normal faults. We applied kinematic GPS surveying and 40Ar/39Ar dating of three cinder cones displaced by two of Group-(2) faults. Kinematic analysis on vertical and horizontal offsets obtained by GPS survey shows that the one fault is now undergoing NE-SW to NNE-SSW extension, consistent with Group (1) fault kinematics. A cinder cone has been displaced 34-40 meters horizontally along this fault, yielding a slow extension rate of 0.02-0.04 mm/yr since 0.8-0.5 Ma. The shift from contraction to extension in the Pasto Ventura region is estimated to be between 7.8 and 0.5 Ma, but more likely between 7.8 and 4 Ma. A regional compilation of kinematics on the southern plateau from this study and existing data, although sparse, shows two spatial groups: the extension directions are N-S to NE-SW south of 26°S latitude, while they are NW-SE to NNW-SSW north of 26°S latitude. Mafic volcanism, thought to indicate the timing of the onset of extension in the Puna, shows a similar pattern, with the oldest ages (up to 7.3 Ma) clustered near 26°S latitude, becoming younger to both the north and the south. Kinematic and

Sensitization of Upper Airway Mechanoreceptors as a New Pharmacologic Principle to Treat Obstructive Sleep Apnea: Investigations with AVE0118 in Anesthetized Pigs

PubMed Central

Wirth, Klaus J.; Steinmeyer, Klaus; Ruetten, Hartmut

2013-01-01

Study Objectives: Drug treatment for obstructive sleep apnea (OSA) is desirable because at least 30% of patients do not tolerate continuous positive airway pressure (CPAP) treatment. The negative pressure reflex (NPR) involving superficially located mechanoreceptors in the upper airway (UA) is an important mechanism for UA patency inhibitable by topical UA anesthesia (lidocaine). The NPR may serve as a target for pharmacological intervention for a topical treatment of OSA. The objective was to determine the effect of pharmacological augmentation of the NPR on UA collapsibility. Design: We developed a model of UA collapsibility in which application of negative pressures caused UA collapses in spontaneously breathing α-chloralose-urethane anesthetized pigs as indicated by characteristic tracheal pressure and air flow changes. Setting: N/A. Patients or Participants: N/A. Interventions: N/A. Measurements and Results: The potassium channel blocker AVE0118 administered topically to the UA in doses of 1, 3, and 10 mg per nostril sensitized the NPR, shifting the mechanoreceptor response threshold for the genioglossus muscle to more positive pressures (P < 0.001; n = 6 per group) and dose-dependently inhibited UA collapsibility. Ten mg of AVE0118 prevented UA collapses against negative pressures of -150 mbar (P < 0.01) for > 4 h in all pigs, while in control pigs the UA collapsed at -50 mbar or less negative pressures. The effect of AVE0118 was abolished by UA lidocaine anesthesia. Acute intravenous administration of naloxone or acetazolamide was ineffective; paroxetine and mirtazepine were weakly effective and fluoxetine was moderately effective in line with reported clinical efficacy. Conclusion: Topical administration of AVE0118 to the UA is a promising pharmacologic approach for the treatment of OSA. Citation: Wirth KJ; Steinmeyer K; Ruetten H. Sensitization of upper airway mechanoreceptors as a new pharmacologic principle to treat obstructive sleep apnea

Data for NASA's AVE 4 experiment: 25-mb sounding data and synoptic charts

NASA Technical Reports Server (NTRS)

Fucik, N. F.; Turner, R. E.

1975-01-01

The AVE 4 Experiment is described and tabulated rawinsonde data at 25-mb intervals from the surface to 25 mb for the 42 stations participating in the experiment are presented. Soundings were taken between 0000 GMT, April 24 and 1200 GMT, April 25, 1975. The methods of data processing and accuracy are discussed. Synoptic charts prepared from the data are presented, as well as an example of contact data.

Data for NASA's AVE 4 experiment: 25 mb sounding data and synoptic charts

NASA Technical Reports Server (NTRS)

Fucik, N. F.; Turner, R. E.

1976-01-01

The AVE IV Experiment is described and tabulated rawinsonde data at 25 mb intervals from the surface to 25 mb for the 42 stations participating in the experiment are presented. Soundings were taken between 0000 GMT, April 24, and 1,200 GMT, April 25, 1975. The methods of data processing and accuracy are briefly discussed. Synoptic charts prepared from the data are presented, as well as an example of contact data.

Effect of AVE 0991 angiotensin-(1-7) receptor agonist treatment on elemental and biomolecular content and distribution in atherosclerotic plaques of apoE-knockout mice

NASA Astrophysics Data System (ADS)

Kowalska, J.; Gajda, M.; Jawień, J.; Kwiatek, W. M.; Appel, K.; Dumas, P.

2013-12-01

Gene-targeted apolipoprotein E-knockout (apoE-KO) mice display early and highly progressive vascular lesions containing lipid deposits and they became a reliable animal model to study atherosclerosis. The aim of the present study was to investigate the effect of AVE 0991 angiotensin-(1-7) receptor agonist on the distribution of selected pro- and anti- inflammatory elements as well as biomolecules in atherosclerotic plaques of apoE-knockout mice. Synchrotron radiation-based X-ray fluorescence (micro-XRF) and Fourier Transform Infrared (micro-FTIR) microspectroscopies were applied. Two-month-old apoE-KO mice were fed for following four months diet supplemented with AVE 0991 (0.58 μmol/kg b.w. per day). Histological sections of ascending aortas were analyzed spectroscopically. The distribution of P, Ca, Fe and Zn were found to correspond with histological structure of the lesion. Significantly lower contents of P, Ca, Zn and significantly higher content of Fe were observed in animals treated with AVE 0991. Biomolecular analysis showed lower lipids saturation level and lower lipid to protein ratio in AVE 0991 treated group. Protein secondary structure was studied according to the composition of amide I band (1660 cm-1) and it demonstrated higher proportion of β-sheet structure as compared to α-helix in both studied groups.

Renoprotective Effects of AVE0991, a Nonpeptide Mas Receptor Agonist, in Experimental Acute Renal Injury

PubMed Central

Barroso, Lívia Corrêa; Silveira, Kátia Daniela; Lima, Cristiano Xavier; Borges, Valdinéria; Bader, Michael; Rachid, Milene; Santos, Robson Augusto Souza; Souza, Danielle Gloria; Simões e Silva, Ana Cristina; Teixeira, Mauro Martins

2012-01-01

Renal ischemia and reperfusion (I/R) is the major cause of acute kidney injury in hospitalized patients. Mechanisms underlying reperfusion-associated injury include recruitment and activation of leukocytes and release of inflammatory mediators. In this study, we investigated the renal effects of acute administration of AVE0991, an agonist of Mas, the angiotensin-(1–7) receptor, the angiotensin-(1–7) receptor, in a murine model of renal I/R. Male C57BL/6 wild-type or Mas−/− mice were subjected to 30 min of bilateral ischemia and 24 h of reperfusion. Administration of AVE0991 promoted renoprotective effects, as seen by improvement of function, decreased tissue injury, prevention of local and remote leucocyte infiltration, and release of the chemokine, CXCL1. I/R injury was similar in WT and Mas−/− mice, suggesting that endogenous activation of this receptor does not control renal damage under baseline conditions. In conclusion, pharmacological interventions using Mas receptor agonists may represent a therapeutic opportunity for the treatment of renal I/R injury. PMID:22319645

Manual de métodos de campo para el monitoreo de aves terrestres

Treesearch

C. John Ralph; Geoffrey R. Geupel; Peter Pyle; Thomas E. Martin; David F DeSante; Borja Milá

1996-01-01

El presente manual es una recopilación de métodos de campo para la determinación de índices de abundancia y datos demográficos de poblaciones de aves terrestres en una amplia variedad de hábitats. Está dirigido a biólogos, técnicos de campo, e investigadores de cualquier parte del Continente Americano. Los métodos descritos incluyen cuatro tipos de censos...

Quill mites in Brazilian psittacine birds (Aves: Psittaciformes).

PubMed

Jardim, Cassius Catão Gomes; Cunha, Lucas Maciel; Rezende, Leandro do Carmo; Teixeira, Cristina Mara; Martins, Nelson Rodrigo da Silva; de Oliveira, Paulo Roberto; Leite, Romário Cerqueira; Faccini, João Luiz Horácio; Leite, Rômulo Cerqueira

2012-09-01

The primary and secondary feathers of 170 Brazilian psittacine birds (Aves: Psittaciformes) were examined in order to identify feather quill mite fauna. Birds were held captive in two locations in the state of Minas Gerais (MG), and two in the state of Espirito Santo (ES). The quills were cut longitudinally and were examined under optical microscopy. The genus of quill mites most frequently found was Paralgopsis (Astigmata: Pyrogliphidae), followed by Cystoidosoma (Astigmata: Syringobiidae). Astigmata: Syringophilidae mites were sporadically observed. After analyzing the data using logistic regression models, it was determined that there was higher infestation risk for psittacines in ES state, as compared with those in MG, and a significant increase in risk depending on the psittacine host species. However, the location of captivity did not have a significant effect. Lesions were observed in infested feathers. Cystoidosoma sp. and Paralgopsis sp. were always observed together, with parts of Paralgopsis found inside Cystoidosoma sp., suggesting thanatochresis or predation.

A comparison between Nimbus 5 THIR and ITPR temperatures and derived winds with rawinsonde data obtained in the AVE 2 experiment

NASA Technical Reports Server (NTRS)

Arnold, J. E.; Scoggins, J. R.; Fuelberg, H. E.

1976-01-01

During the period of May 11 and 12, 1974, NASA conducted its second Atmospheric Variability Experiment (AVE II) over the eastern United States. In this time interval, two Nimbus 5 orbits crossed the AVE II area, providing a series of ITPR soundings as well as THIR data. Horizontal temperature mapping of the AVE II cloud field is examined using two grid print map scales. Implied cloud top heights are compared with maximum radar-echo top reports. In addition, shelter temperatures in areas of clear sky are compared with the surface temperatures as determined from 11.5 micrometer radiometer data of the THIR experiment. The ITPR sounding accuracy is evaluated using interpolated radiosonde temperatures at times nearly coincident with the ITPR soundings. It was found that mean differences between the two data sets were as small as 1.3 C near 500 mb and as large as 2.9 C near the tropopause. The differences between ITPR and radiosonde temperatures at constant pressure levels were sufficient to induce significant differences in the horizontal temperature gradient. Cross sections of geostrophic wind along the orbital tracks were developed using a thermal wind buildup based on the ITPR temperature data and the radiosonde temperature data. Differences between the radiosonde and ITPR geostrophic winds could be explained on the basis of differences in the ITPR and radiosonde temperature gradients.

Impacts of nonnative invasive species on US forests and recommendations for policy and management

Treesearch

W. Keith Moser; Edward L. Barnard; Ronald F. Billings; Susan J. Crocker; Andrew N. Gray; George G. Ice; Mee-Sook Kim; Richard Reid; Sue U. Rodman; William H. McWilliams

2009-01-01

The introduction of nonnative invasive species (NNIS) into the United States has had tremendous impacts on the nation's commercial and urban forest resources. Of principal concern are the effects of NNIS on forest composition, structure, function, productivity, and patterns of carbon sequestration. In 2006, the Society of American Foresters commissioned an ad hoc...

Motion Rehab AVE 3D: A VR-based exergame for post-stroke rehabilitation.

PubMed

Trombetta, Mateus; Bazzanello Henrique, Patrícia Paula; Brum, Manoela Rogofski; Colussi, Eliane Lucia; De Marchi, Ana Carolina Bertoletti; Rieder, Rafael

2017-11-01

Recent researches about games for post-stroke rehabilitation have been increasing, focusing in upper limb, lower limb and balance situations, and showing good experiences and results. With this in mind, this paper presents Motion Rehab AVE 3D, a serious game for post-stroke rehabilitation of patients with mild stroke. The aim is offer a new technology in order to assist the traditional therapy and motivate the patient to execute his/her rehabilitation program, under health professional supervision. The game was developed with Unity game engine, supporting Kinect motion sensing input device and display devices like Smart TV 3D and Oculus Rift. It contemplates six activities considering exercises in a tridimensional space: flexion, abduction, shoulder adduction, horizontal shoulder adduction and abduction, elbow extension, wrist extension, knee flexion, and hip flexion and abduction. Motion Rehab AVE 3D also report about hits and errors to the physiotherapist evaluate the patient's progress. A pilot study with 10 healthy participants (61-75 years old) tested one of the game levels. They experienced the 3D user interface in third-person. Our initial goal was to map a basic and comfortable setup of equipment in order to adopt later. All the participants (100%) classified the interaction process as interesting and amazing for the age, presenting a good acceptance. Our evaluation showed that the game could be used as a useful tool to motivate the patients during rehabilitation sessions. Next step is to evaluate its effectiveness for stroke patients, in order to verify if the interface and game exercises contribute into the motor rehabilitation treatment progress. Copyright © 2017 Elsevier B.V. All rights reserved.

A new species of Acroleptus Bourgeois (Coleoptera: Lycidae) from the Brazilian Amazonian rainforest, with a note on its homonymy with Acroleptus Cabanis (Aves).

PubMed

Ferreira, Vinicius S

2015-04-24

Acroleptus costae sp. nov. is described from the Brazilian Amazonian rainforest, raising the diversity of the formerly monotypic genus to two known species. The validity of Acroleptus Bourgeois, 1886 (Insecta) is maintained while Acroleptus Cabanis, 1861 (Aves) is considered to be an incorrect subsequent spelling.

AveBoost2: Boosting for Noisy Data

NASA Technical Reports Server (NTRS)

Oza, Nikunj C.

2004-01-01

AdaBoost is a well-known ensemble learning algorithm that constructs its constituent or base models in sequence. A key step in AdaBoost is constructing a distribution over the training examples to create each base model. This distribution, represented as a vector, is constructed to be orthogonal to the vector of mistakes made by the pre- vious base model in the sequence. The idea is to make the next base model's errors uncorrelated with those of the previous model. In previous work, we developed an algorithm, AveBoost, that constructed distributions orthogonal to the mistake vectors of all the previous models, and then averaged them to create the next base model s distribution. Our experiments demonstrated the superior accuracy of our approach. In this paper, we slightly revise our algorithm to allow us to obtain non-trivial theoretical results: bounds on the training error and generalization error (difference between training and test error). Our averaging process has a regularizing effect which, as expected, leads us to a worse training error bound for our algorithm than for AdaBoost but a superior generalization error bound. For this paper, we experimented with the data that we used in both as originally supplied and with added label noise-a small fraction of the data has its original label changed. Noisy data are notoriously difficult for AdaBoost to learn. Our algorithm's performance improvement over AdaBoost is even greater on the noisy data than the original data.

Using the Spanish Online Resource "Aula Virtual de Espanol" (AVE) to Promote a Blended Teaching Approach in High School Spanish Language Classrooms

ERIC Educational Resources Information Center

Pellerin, Martine; Montes, Carlos Soler

2012-01-01

The study explores the effectiveness of the implementation of blended teaching (BT) by combining the Spanish online resource "Aula Virtual de Espanol" (AVE) with the face-to-face (F2F) delivery approach in second language Spanish programs in two high schools in Alberta, Canada. Findings demonstrate the effectiveness of combining the…

Codon usage bias and phylogenetic analysis of mitochondrial ND1 gene in pisces, aves, and mammals.

PubMed

Uddin, Arif; Choudhury, Monisha Nath; Chakraborty, Supriyo

2018-01-01

The mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 (MT-ND1) gene is a subunit of the respiratory chain complex I and involved in the first step of the electron transport chain of oxidative phosphorylation (OXPHOS). To understand the pattern of compositional properties, codon usage and expression level of mitochondrial ND1 genes in pisces, aves, and mammals, we used bioinformatic approaches as no work was reported earlier. In this study, a perl script was used for calculating nucleotide contents and different codon usage bias parameters. The codon usage bias of MT-ND1 was low but the expression level was high as revealed from high ENC and CAI value. Correspondence analysis (COA) suggests that the pattern of codon usage for MT-ND1 gene is not same across species and that compositional constraint played an important role in codon usage pattern of this gene among pisces, aves, and mammals. From the regression equation of GC12 on GC3, it can be inferred that the natural selection might have played a dominant role while mutation pressure played a minor role in influencing the codon usage patterns. Further, ND1 gene has a discrepancy with cytochrome B (CYB) gene in preference of codons as evident from COA. The codon usage bias was low. It is influenced by nucleotide composition, natural selection, mutation pressure, length (number) of amino acids, and relative dinucleotide composition. This study helps in understanding the molecular biology, genetics, evolution of MT-ND1 gene, and also for designing a synthetic gene.

Reliability of a New Radiographic Classification for Developmental Dysplasia of the Hip.

PubMed

Narayanan, Unni; Mulpuri, Kishore; Sankar, Wudbhav N; Clarke, Nicholas M P; Hosalkar, Harish; Price, Charles T

2015-01-01

Existing radiographic classification schemes (eg, Tönnis criteria) for DDH quantify the severity of disease based on the position of the ossific nucleus relative to Hilgenreiner's and Perkin's lines. By definition, this method requires the presence of an ossification centre, which can be delayed in appearance and eccentric in location within the femoral head. A new radiographic classification system has been developed by the International Hip Dysplasia Institute (IHDI), which uses the mid-point of the proximal femoral metaphysis as a reference landmark, and can therefore be applied to children of all ages. The purpose of this study was to compare the reliability of this new method with that of Tönnis, as the first step in establishing its validity and clinical utility. Twenty standardized anteroposterior pelvic radiographs of children with untreated DDH were selected purposefully to capture the spectrum of age (range, 3 to 32 mo) at presentation and disease severity. Each of the hips was classified separately by the IHDI and Tönnis methods by 6 experienced pediatric orthopaedists from the United States, Canada, Mexico, United Kingdom, and by 2 orthopaedic senior residents. The inter-rater reliability was tested using the Intra Class Correlation coefficient (ICC) to measure concordance between raters. All 40 hips were classifiable by the IHDI method by all raters. Ten of the 40 hips could not be classified by the Tönnis method because of the absence of the ossific nucleus on one or both sides. The ICC (95% confidence interval) for the IHDI method for all raters was 0.90 (0.83-0.95) and 0.95 (0.91-0.98) for the right and left hips, respectively. The corresponding ICCs for the Tönnis method were 0.63 (0.46-0.80) and 0.60 (0.43-0.78), respectively. There was no significant difference between the ICCs of the 6 experts and 2 trainees. The IHDI method of classification has excellent inter-rater reliability, both among experts and novices, and is more widely

The Chewing Lice (Insecta, Phthiraptera) Fauna of the Swainson's Warbler, Limnothlypis swainsonii (Aves, Parulidae).

PubMed

Valim, Michel P; Reiley, Bryan M

2015-09-01

We examined Swainson's warblers (Limnothlypis swainsonii (Audubon, 1834), Aves: Parulidae) for lice fauna during 2 yr at three study sites in Arkansas, USA. A total of 66 individuals were examined; eight birds (10.6%) were parasitized with 16 lice of two new species belonging to two genera Myrsidea Waterson, 1915 (Amblycera: Menoponidae) and Brueelia Kéler, 1936 (Ischnocera: Philopteridae). Parasitological parameter data are given on the prevalence of lice on Swainson's warblers. Species descriptions and illustrations are provided for Myrsidea bensoni sp. nov. and Brueelia limnothlypiae sp. nov.; including a key for females of the genus Myrsidea that parasitize Parulidae (Passeriformes). © The Authors 2015. Published by Oxford University Press on behalf of Entomological Society of America. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Evidence of a possible NNE-trending fault zone in the Summerville, South Carolina, area from shallow seismic reflection surveys

DOE Office of Scientific and Technical Information (OSTI.GOV)

Marple, R.T.; Talwani, P.

1994-03-01

Five high-resolution seismic-reflection surveys trending approximately WNW-ESE and totaling about 31 km were acquired in the Summerville, South Carolina, area. The surveys trend across the postulated Woodstock fault zone. These newly acquired data together with earlier data revealed the existence of an [approximately]50-km-long feature associated with gentle warping of the shallow sediments that lies along a recently described zone of river anomalies (ZRA). The first ([approximately]5.9-km-long) seismic reflection profile located about 14 km NNE of Summerville revealed that the J reflector (basalt) at about 670 m depth is offset about 30--40 m with the west side up. The overlying sedimentsmore » displayed upwarping rather than brittle offset. A second ([approximately]6.7-km-long) survey located along interstate Highway 26 revealed as much as 30--40 m of upwarping of the sediments above about 450 m depth. A third ([approximately]7.3-km-long) profile acquired through the town of Summerville revealed four, [approximately]200--300 m wide, nearly vertical zones in which the reflectors are noncoherent. Away from these zones the reflectors are relatively flat and are slightly higher on the west side of each zone. The fourth (3-km-long) survey was located about 5 km SW of Middleton Gardens and indicated minor faulting at about 500 m depth. The fifth ([approximately]6.4-km-long) seismic survey acquired just north of Ravenel revealed an [approximately]0.5-km-wide zone in which the reflectors in the top 350 m displayed as much as 20 m of upwarping. On all the surveys, except for the first, the basalt was at too great a depth to be resolved.« less

The development of convective instability, wind shear, and vertical motion in relation to convection activity and synoptic systems in AVE 4

NASA Technical Reports Server (NTRS)

Davis, J. G.; Scoggins, J. R.

1981-01-01

Data from the Fourth Atmospheric Variability Experiment were used to investigate conditions/factors responsible for the development (local time rate-of-change) of convective instability, wind shear, and vertical motion in areas with varying degrees of convective activity. AVE IV sounding data were taken at 3 or 6 h intervals during a 36 h period on 24-25 April 1975 over approximately the eastern half of the United States. An error analysis was performed for each variable studied.

Molecular phylogeny of the spoonbills (Aves: Threskiornithidae) based on mitochondrial DNA

USGS Publications Warehouse

Chesser, R. Terry; Yeung, Carol K.L.; Yao, Cheng-Te; Tian, Xiu-Hua; Li, Shou-Hsien

2010-01-01

Spoonbills (genus Platalea) are a small group of wading birds, generally considered to constitute the subfamily Plataleinae (Aves: Threskiornithidae). We reconstructed phylogenetic relationships among the six species of spoonbills using variation in sequences of the mitochondrial genes ND2 and cytochrome b (total 1796 bp). Topologies of phylogenetic trees reconstructed using maximum likelihood, maximum parsimony, and Bayesian analyses were virtually identical and supported monophyly of the spoonbills. Most relationships within Platalea received strong support: P. minor and P. regia were closely related sister species, P. leucorodia was sister to the minor-regia clade, and P. alba was sister to the minor-regia-leucorodia clade. Relationships of P. flavipes and P. ajaja were less well resolved: these species either formed a clade that was sister to the four-species clade, or were successive sisters to this clade. This phylogeny is consistent with ideas of relatedness derived from spoonbill morphology. Our limited sampling of the Threskiornithinae (ibises), the putative sister group to the spoonbills, indicated that this group is paraphyletic, in agreement with previous molecular data; this suggests that separation of the Threskiornithidae into subfamilies Plataleinae and Threskiornithinae may not be warranted.

Niche evolution and diversification in a Neotropical radiation of birds (Aves: Furnariidae).

PubMed

Seeholzer, Glenn F; Claramunt, Santiago; Brumfield, Robb T

2017-03-01

Rapid diversification may be caused by ecological adaptive radiation via niche divergence. In this model, speciation is coupled with niche divergence and lineage diversification is predicted to be correlated with rates of niche evolution. Studies of the role of niche evolution in diversification have generally focused on ecomorphological diversification but climatic-niche evolution may also be important. We tested these alternatives using a phylogeny of 298 species of ovenbirds (Aves: Furnariidae). We found that within Furnariidae, variation in species richness and diversification rates of subclades were best predicted by rate of climatic-niche evolution than ecomorphological evolution. Although both are clearly important, univariate regression and multivariate model averaging more consistently supported the climatic-niche as the best predictor of lineage diversification. Our study adds to the growing body of evidence, suggesting that climatic-niche divergence may be an important driver of rapid diversification in addition to ecomorphological evolution. However, this pattern may depend on the phylogenetic scale at which rate heterogeneity is examined. © 2017 The Author(s). Evolution © 2017 The Society for the Study of Evolution.

The Spanish national health care-associated infection surveillance network (INCLIMECC): data summary January 1997 through December 2006 adapted to the new National Healthcare Safety Network Procedure-associated module codes.

PubMed

Pérez, Cristina Díaz-Agero; Rodela, Ana Robustillo; Monge Jodrá, Vincente

2009-12-01

In 1997, a national standardized surveillance system (designated INCLIMECC [Indicadores Clínicos de Mejora Continua de la Calidad]) was established in Spain for health care-associated infection (HAI) in surgery patients, based on the National Nosocomial Infection Surveillance (NNIS) system. In 2005, in its procedure-associated module, the National Healthcare Safety Network (NHSN) inherited the NNIS program for surveillance of HAI in surgery patients and reorganized all surgical procedures. INCLIMECC actively monitors all patients referred to the surgical ward of each participating hospital. We present a summary of the data collected from January 1997 to December 2006 adapted to the new NHSN procedures. Surgical site infection (SSI) rates are provided by operative procedure and NNIS risk index category. Further quality indicators reported are surgical complications, length of stay, antimicrobial prophylaxis, mortality, readmission because of infection or other complication, and revision surgery. Because the ICD-9-CM surgery procedure code is included in each patient's record, we were able to reorganize our database avoiding the loss of extensive information, as has occurred with other systems.

Impact evaluation of lighting retrofit projects at Boeing Commercial Airplane Group under The Energy $avings Plan

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sullivan, G.P.; Oens, M.A.; Spanner, G.E.

1994-01-01

This impact evaluation of two lighting retrofit projects that were recently installed at Boeing Commercial Airplane Group (Boeing) was conducted for the Bonneville Power Administration (Bonneville) as part of an evaluation of its Energy $avings Plan (E$P) Program. The first project was a light-fixture and lighting control retrofit, consisting of five individual measures installed in Building 40-05. The second project was a retrofit of all parking lot lighting on the site. The objective of this impact evaluation was to assess how much electrical energy is being saved at Boeing as a result of the E$P projects and to determine howmore » much the savings cost Bonneville and the region. The impact of the project was evaluated with a combination of engineering analysis, financial analysis, interviews, and submittal reviews (Boeing`s proposals and completion reports).« less

Cross-Genotypic Examination of Hepatitis C Virus Polymerase Inhibitors Reveals a Novel Mechanism of Action for Thumb Binders

PubMed Central

Eltahla, Auda A.; Tay, Enoch; Douglas, Mark W.

2014-01-01

Direct-acting antivirals (DAAs) targeting proteins encoded by the hepatitis C virus (HCV) genome have great potential for the treatment of HCV infections. However, the efficacy of DAAs designed to target genotype 1 (G1) HCV against non-G1 viruses has not been characterized fully. In this study, we investigated the inhibitory activities of nonnucleoside inhibitors (NNIs) against the HCV RNA-dependent RNA polymerase (RdRp). We examined the ability of six NNIs to inhibit G1b, G2a, and G3a subgenomic replicons in cell culture, as well as in vitro transcription by G1b and G3a recombinant RdRps. Of the six G1 NNIs, only the palm II binder nesbuvir demonstrated activity against G1, G2, and G3 HCV, in both replicon and recombinant enzyme models. The thumb I binder JTK-109 also inhibited G1b and G3a replicons and recombinant enzymes but was 41-fold less active against the G2a replicon. The four other NNIs, which included a palm I binder (setrobuvir), two thumb II binders (lomibuvir and filibuvir), and a palm β-hairpin binder (tegobuvir), all showed at least 40-fold decreases in potency against G2a and G3a replicons and the G3a enzyme. This antiviral resistance was largely conferred by naturally occurring amino acid residues in the G2a and G3a RdRps that are associated with G1 resistance. Lomibuvir and filibuvir (thumb II binders) inhibited primer-dependent but not de novo activity of the G1b polymerase. Surprisingly, these compounds instead specifically enhanced the de novo activity at concentrations of ≥100 nM. These findings highlight a potential differential mode of RdRp inhibition for HCV NNIs, depending on their prospective binding pockets, and also demonstrate a surprising enhancement of de novo activity for thumb RdRp binders. These results also provide a better understanding of the antiviral coverage for these polymerase inhibitors, which will likely be used in future combinational interferon-free therapies. PMID:25246395

Broad-spectrum non-nucleoside inhibitors for caliciviruses.

PubMed

Netzler, Natalie E; Enosi Tuipulotu, Daniel; Eltahla, Auda A; Lun, Jennifer H; Ferla, Salvatore; Brancale, Andrea; Urakova, Nadya; Frese, Michael; Strive, Tanja; Mackenzie, Jason M; White, Peter A

2017-10-01

Viruses of the Caliciviridae cause significant and sometimes lethal diseases, however despite substantial research efforts, specific antivirals are lacking. Broad-spectrum antivirals could combat multiple viral pathogens, offering a rapid solution when no therapies exist. The RNA-dependent RNA polymerase (RdRp) is an attractive antiviral target as it is essential for viral replication and lacks mammalian homologs. To focus the search for pan-Caliciviridae antivirals, the RdRp was probed with non-nucleoside inhibitors (NNIs) developed against hepatitis C virus (HCV) to reveal both allosteric ligands for structure-activity relationship enhancement, and highly-conserved RdRp pockets for antiviral targeting. The ability of HCV NNIs to inhibit calicivirus RdRp activities was assessed using in vitro enzyme and murine norovirus cell culture assays. Results revealed that three NNIs which bound the HCV RdRp Thumb I (TI) site also inhibited transcriptional activities of six RdRps spanning the Norovirus, Sapovirus and Lagovirus genera of the Caliciviridae. These NNIs included JTK-109 (RdRp inhibition range: IC 50 4.3-16.6 μM), TMC-647055 (IC 50 range: 18.8-45.4 μM) and Beclabuvir (IC 50 range: 23.8->100 μM). In silico studies and site-directed mutagenesis indicated the JTK-109 binding site was within the calicivirus RdRp thumb domain, in a pocket termed Site-B, which is highly-conserved within all calicivirus RdRps. Additionally, RdRp inhibition assays revealed that JTK-109 was antagonistic with the previously reported RdRp inhibitor pyridoxal-5'-phosphate-6-(2'-naphthylazo-6'-nitro-4',8'-disulfonate) tetrasodium salt (PPNDS), that also binds to Site-B. Moreover, like JTK-109, PPNDS was also a potent inhibitor of polymerases from six viruses spanning the three Caliciviridae genera tested (IC 50 range: 0.1-2.3 μM). Together, this study demonstrates the potential for de novo development of broad-spectrum antivirals that target the highly-conserved RdRp thumb pocket

Embodying animals: Body-part compatibility in mammalian, reptile and aves classes.

PubMed

Pacione, Sandra M; Welsh, Timothy N

2015-09-01

The purpose of the present study was to determine how humans code homologous body parts of nonhuman mammal, reptilian, and aves animals with respect to the representation of the human body. To this end, participants completed body-part compatibility tasks in which responses were executed to colored targets that were superimposed over the upper limbs, lower limbs or head of different animals in different postures. In Experiment 1, the images were of meekats and lizards in bipedal and quadrupedal postures. In Experiment 2, the images were of a human, a penguin, and an owl in a bipedal posture with upper limbs stretched out. Overall, the results revealed that the limbs of nonhuman mammals (meerkat and human) were consistently mapped onto the homologous human body parts only when the mammals were in a bipedal posture. Specifically, body-part compatibility effects emerged for the human and the meerkat in a bipedal posture, but not the meerkat in the quadrupedal posture. Further, consistent body-part compatibility effects were not observed for the lizard in the quadrupedal posture or for the lizard, penguin, or owl in a bipedal posture. The pattern of results suggests that the human bipedal body representation may distinguish taxonomical classes and is most highly engaged when viewing homologous body parts of mammalian animals. Copyright © 2015 Elsevier B.V. All rights reserved.

Characteristics of ageostrophic flow in the vicinity of a severe weather outbreak - AVE-SESAME I

NASA Technical Reports Server (NTRS)

Arnold, J. E.

1982-01-01

GOES satellite data was used to examine the ageostrophic flow in the vicinity of severe weather outbreaks along the Red River between Texas and Oklahoma in April 1979. The observations were part of the NASA AVE-SESAME I data on atmospheric states close to severe weather conditions. The Barnes Objective Analysis Technique was employed to analyze the data on a 100 km grid. The ageostrophic wind was defined on a regional scale from satellite data on different levels of cloud wind vectors, with a height change signalling a short-wave system in a long-wave trough. The percentage of deviation of the subgeostrophic winds from the geostrophic wind was calculated, and maximum departure corresponded with the region of greatest storm development. Time cross sections of additions to the ageostrophic flow were made as a function of pressure at 100 mb intervals from 900-100 mb. The ageostrophic acceleration was consistently twice the geostrophic acceleration.

Neonicotinoid pesticides in drinking water in agricultural regions of southern Ontario, Canada.

PubMed

Sultana, Tamanna; Murray, Craig; Kleywegt, Sonya; Metcalfe, Chris D

2018-07-01

Because of the persistence and solubility of neonicotinoid insecticides (NNIs), there is concern that these compounds may contaminate sources of drinking water. The objective of this project was to evaluate the distribution of NNIs in raw and treated drinking water from selected municipalities that draw their water from the lower Great Lakes in areas of southern Ontario, Canada where there is high intensity agriculture. Sites were monitored using Polar Organic Chemical Integrative Samplers (POCIS) and by collecting grab samples at six drinking water treatment plants. Thiamethoxam, clothianidin and imidacloprid were detected in both POCIS and grab samples of raw water. The frequency of detection of NNIs was much lower in treated drinking water, but some compounds were still detected at estimated concentrations in the low ng L -1 range. Thiamethoxam was detected in one grab sample of raw drinking water at a mean concentration of 0.28 μg L -1 , which is above the guidelines for drinking water recommended in some jurisdictions, including the European Union directive on pesticide levels <0.1 μg L -1 in water intended for human consumption. Further work is required to determine whether contamination of sources of drinking water with this class of insecticides is a global problem in agricultural regions. Copyright © 2018 Elsevier Ltd. All rights reserved.

A kinetic energy study of the meso beta-scale storm environment during AVE-SESAME 5 (20-21 May 1979)

NASA Technical Reports Server (NTRS)

Printy, M. F.; Fuelberg, H. E.

1984-01-01

Kinetic energy of the near storm environment was analyzed by meso beta scale data. It was found that horizontal winds in the 400 to 150 mb layer strengthen rapidly north of the developing convection. Peak values then decrease such that the maximum disappears 6 h later. Southeast of the storms, wind speeds above 300 mb decrease nearly 50% during the 3 h period of most intense thunderstorm activity. When the convection dissipates, wind patterns return to prestorm conditions. The mesoscale storm environment of AVE-SESAME 5 is characterized by large values of cross contour generation of kinetic energy, transfers of energy to nonresolvable scales of motion, and horizontal flux divergence. These processes are maximized within the upper troposphere and are greatest during times of strongest convection. It is shown that patterns agree with observed weather features. The southeast area of the network is examined to determine causes for vertical wind variations.

A new look at the holotype and type locality of Setopagis maculosa (Todd, 1920) Aves: Caprimulgidae), with remarks on its systematic relationships.

PubMed

Costa, Thiago V V; Ingels, Johan; Cavarzere, Vagner; Silveira, Luís Fábio

2015-08-12

Setopagis maculosa (Todd, 1920) (Aves: Caprimulgidae) was described based on a single male specimen collected by Samuel Milton Klages in French Guiana, northeastern South America. Since then, no new specimens have been collected nor have any reliable records been made, and the validity of the species has been questioned. A detailed analysis of the holotype reveals that it has unique and distinctive morphological traits that support the validity and taxonomic status of the species, which is provisionally placed in Setopagis. We present new information on the type locality at the time of its collection, which may shed some light on the habitat preferences of the species, and we provide details on its plumage that have been largely overlooked and that will be important for future field identification.

Effect of deuteration on metabolism and clearance of Nerispirdine (HP184) and AVE5638.

PubMed

Schofield, Joseph; Derdau, Volker; Atzrodt, Jens; Zane, Patricia; Guo, Zuyu; van Horn, Robert; Czepczor, Valérie; Stoltz, Axelle; Pardon, Magalie

2015-07-01

Replacing hydrogen with deuterium as a means of altering ADME properties of drug molecules has recently enjoyed a renaissance, such that at least two deuterated chemical entities are currently in clinical development. Although most research in this area aims to increase the metabolic stability, and hence half-life of the active species, experience has shown that prediction of the in vivo behaviour of deuterated molecules is difficult and depends on multiple factors including the complexity of the metabolic scheme, the enzymes involved and hence the mechanism of the rate-determining step in the biotransformation. In an effort to elucidate some of these factors we examined the metabolic behaviour of two molecules from the Sanofi portfolio in a range of in vitro and in vivo systems. Although some key metabolic reactions of the acetylcholine release stimulator HP184 4 were slowed in vitro and in vivo when deuterium was present at the sites of metabolism, this did not translate to an increase in overall metabolic stability. By contrast, the tryptase inhibitor AVE5638 13 was much more metabolically stable in vitro in its deuterated form than when unlabelled. These results indicate that it could be of value to concentrate efforts in this area to molecules which are metabolised by a major pathway that involves enzymes of the amine oxidase family or other low-capacity enzyme families. Copyright © 2015 Elsevier Ltd. All rights reserved.

Incidence of surgical-site infections and the validity of the National Nosocomial Infections Surveillance System risk index in a general surgical ward in Santa Cruz, Bolivia.

PubMed

Soleto, Lorena; Pirard, Marianne; Boelaert, Marleen; Peredo, Remberto; Vargas, Reinerio; Gianella, Alberto; Van der Stuyft, Patrick

2003-01-01

To estimate the frequency of and risk factors for surgical-site infections (SSIs) in Bolivia, and to study the performance of the National Nosocomial Infections Surveillance (NNIS) System risk index in a developing country. A prospective study with patient follow-up until the 30th postoperative day. A general surgical ward of a public hospital in Santa Cruz, Bolivia. Patients admitted to the ward between July 1998 and June 1999 on whom surgical procedures were performed. Follow-up was complete for 91.5% of 376 surgical procedures. The overall SSI rate was 12%. Thirty-four (75.6%) of the 45 SSIs were culture positive. A logistic regression model retained an American Society of Anesthesiologists score of more than 1 (odds ratio [OR], 1.87), a not-clean wound class (OR, 2.28), a procedure duration of more than 1 hour (OR, 1.81), and drain (OR, 1.98) as independent risk factors for SSI. There was no significant association between the NNIS System risk index and SSI rates. However, a "local" risk index constructed with the above cutoff points showed a linear trend with SSI (P < .001) and a relative risk of 3.18 for risk class 3 versus a class of less than 3. SSIs cause considerable morbidity in Santa Cruz. Appropriate nosocomial infection surveillance and control should be introduced. The NNIS System risk index did not discriminate between patients at low and high risk for SSI in this hospital setting, but a risk score based on local cutoff points performed substantially better.

Combined intensive nutrition education and micronutrient powder supplementation improved nutritional status of mildly wasted children on Nias Island, Indonesia.

PubMed

Inayati, Dyah A; Scherbaum, Veronika; Purwestri, Ratna C; Wirawan, Nia N; Suryantan, Julia; Hartono, Susan; Bloem, Maurice A; Pangaribuan, Rosnani V; Biesalski, Hans K; Hoffmann, Volker; Bellows, Anne C

2012-01-01

To assess the impact of intensive nutrition education (INE) with or without the provision of micronutrient powder (MNP) on the nutritional status of mildly wasted children in Nias, Indonesia, two groups of mildly wasted (>=-1.5 to <-1.0 WHZ) children aged >=6 to <60 months in the Church World Service (CWS) project areas were assigned by village randomization to receive INE (n=64) or INE+MNP (n=51) in a weekly program. Another two groups of mildly wasted children who were living at a clear distance from INE and INE+MNP villages were selected to receive a monthly non-intensive nutrition education program (NNE) with or without MNP (n=50 both respectively). WHZ, weight, height, haemoglobin (Hb) level, and morbidity data were assessed at admission, during the study, and at individual discharge. Children's weight gain (g/kg body weight/day) was highest in INE+MNP group (2.2±2.1), followed by INE (1.1±0.9), NNE+MNP (0.3±0.5) and NNE (0.3±0.4) group. In both MNP intervention groups (INE+MNP, NNE+MNP), supplements significantly increased Hb value (g/L) of respective children (10.0±10.0; p<0.001 and 3.0±8.0; p<0.05 respectively). Proportion of children who reached discharge criterion was highest among the INE+MNP (70.6%; n=36), followed by INE (64.1%; n=41), NNE+MNP (26.0%; n=13), and NNE (20.0%; n=10) groups (p<0.001). Shortest length of stay until recovery was observed among children in the INE+MNP group (29.9 days), followed by INE (40.0 days), NNE+MNP (80.6 days), and NNE (86.2 days) respectively (p<0.001). Weekly intensive nutrition education supported by MNP supplementation produced the best results regarding weight gain and haemoglobin status of mildly wasted children.

A novel Haemosporida clade at the rank of genus in North American cranes (Aves: Gruiformes).

PubMed

Bertram, Miranda R; Hamer, Sarah A; Hartup, Barry K; Snowden, Karen F; Medeiros, Matthew C; Outlaw, Diana C; Hamer, Gabriel L

2017-04-01

The unicellular blood parasites in the order Haemosporida are highly diverse, infect many vertebrates, are responsible for a large disease burden among humans and animals, and have reemerged as an important model system to understand the evolutionary and ecological dynamics of host-parasite interactions. The phylogenetics and systematics of Haemosporida are limited by poor sampling of different vertebrate host taxa. We surveyed the Haemosporida of wild whooping cranes (Grus americana) and sandhill cranes (Grus canadensis) (Aves: Gruiformes) using a combination of morphological and molecular approaches. We identified Haemoproteus antigonis in blood smears based on published morphological descriptions. Phylogenetic analysis based on partial cytochrome b (cytb) and cytochrome oxidase (coI) sequences placed H. antigonis parasites in a novel clade, distinct from all avian Haemosporida genera for which cytb and/or coI sequences are available. Molecular clock and divergence estimates suggest this crane clade may represent a new genus. This is the first molecular description of H. antigonis and the first report of H. antigonis in wild whooping cranes, an endangered bird in North America. Further sampling of Haemosporida, especially from hosts of the Gruiformes and other poorly sampled orders, will help to resolve the relationship of the H. antigonis clade to other avian Haemosporida genera. Our study highlights the potential of sampling neglected host species to discover novel lineages of diverse parasite groups. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

Structure and composition of the courtship phenotype in the bird of paradise Parotia lawesii (Aves: Paradisaeidae).

PubMed

Scholes, Edwin

2008-01-01

Ethology is rooted in the idea that behavior is composed of discrete units and sub-units that can be compared among taxa in a phylogenetic framework. This means that behavior, like morphology and genes, is inherently modular. Yet, the concept of modularity is not well integrated into how we envision the behavioral components of phenotype. Understanding ethological modularity, and its implications for animal phenotype organization and evolution, requires that we construct interpretive schemes that permit us to examine it. In this study, I describe the structure and composition of a complex part of the behavioral phenotype of Parotia lawesii Ramsay, 1885--a bird of paradise (Aves: Paradisaeidae) from the forests of eastern New Guinea. I use archived voucher video clips, photographic ethograms, and phenotype ontology diagrams to describe the modular units comprising courtship at various levels of integration. Results show P. lawesii to have 15 courtship and mating behaviors (11 males, 4 females) hierarchically arranged within a complex seven-level structure. At the finest level examined, male displays are comprised of 49 modular sub-units (elements) differentially employed to form more complex modular units (phases and versions) at higher-levels of integration. With its emphasis on hierarchical modularity, this study provides an important conceptual framework for understanding courtship-related phenotypic complexity and provides a solid basis for comparative study of the genus Parotia.

Adaptive collab orative restoration: a key concept in invasive plant management

Treesearch

James H. Miller; John. Schelhas

2009-01-01

Nonnative invasive species (NNIS) present a severe human dilemma due to their collective threat of replacing and damaging human sustaining ecosystems (U.S. Congress Office of Technology Assessment 1993; Mack et al. 2000; Pimentel 2002). Rapid developments in global trade have caught governments and their regulatory agencies unaware and...

dni_slope_filter_2

Science.gov Websites

"GRIDCODE" true true false 19 Double 10 18 ,First,#,int_60,GRIDCODE,-1,-1,int_59,GRIDCODE,-1 ; true true false 19 Double 10 18 ,First,#,int_60,AVE_DNI,-1,-1,int_59,AVE_DNI,-1,-1,int_58,AVE_DNI,-1,-1 ,int_02,AVE_DNI,-1,-1,int_01,AVE_DNI,-1,-1,int_00,AVE_DNI,-1,-1;AVE_GHI "AVE_GHI" true true

dni_slope_filter_4

Science.gov Websites

"GRIDCODE" true true false 19 Double 10 18 ,First,#,int_60,GRIDCODE,-1,-1,int_59,GRIDCODE,-1 ; true true false 19 Double 10 18 ,First,#,int_60,AVE_DNI,-1,-1,int_59,AVE_DNI,-1,-1,int_58,AVE_DNI,-1,-1 ,int_02,AVE_DNI,-1,-1,int_01,AVE_DNI,-1,-1,int_00,AVE_DNI,-1,-1;AVE_GHI "AVE_GHI" true true

dni_slope_filter_5

Science.gov Websites

"GRIDCODE" true true false 19 Double 10 18 ,First,#,int_60,GRIDCODE,-1,-1,int_59,GRIDCODE,-1 ; true true false 19 Double 10 18 ,First,#,int_60,AVE_DNI,-1,-1,int_59,AVE_DNI,-1,-1,int_58,AVE_DNI,-1,-1 ,int_02,AVE_DNI,-1,-1,int_01,AVE_DNI,-1,-1,int_00,AVE_DNI,-1,-1;AVE_GHI "AVE_GHI" true true

dni_slope_filter_1

Science.gov Websites

"GRIDCODE" true true false 19 Double 10 18 ,First,#,int_60,GRIDCODE,-1,-1,int_59,GRIDCODE,-1 ; true true false 19 Double 10 18 ,First,#,int_60,AVE_DNI,-1,-1,int_59,AVE_DNI,-1,-1,int_58,AVE_DNI,-1,-1 ,int_02,AVE_DNI,-1,-1,int_01,AVE_DNI,-1,-1,int_00,AVE_DNI,-1,-1;AVE_GHI "AVE_GHI" true true

dni_slope_filter_3

Science.gov Websites

"GRIDCODE" true true false 19 Double 10 18 ,First,#,int_60,GRIDCODE,-1,-1,int_59,GRIDCODE,-1 ; true true false 19 Double 10 18 ,First,#,int_60,AVE_DNI,-1,-1,int_59,AVE_DNI,-1,-1,int_58,AVE_DNI,-1,-1 ,int_02,AVE_DNI,-1,-1,int_01,AVE_DNI,-1,-1,int_00,AVE_DNI,-1,-1;AVE_GHI "AVE_GHI" true true

An analysis of the AVE-SESAME I period using statistical structure and correlation functions. [Atmospheric Variability Experiment-Severe Environmental Storm and Mesoscale Experiment

NASA Technical Reports Server (NTRS)

Fuelberg, H. E.; Meyer, P. J.

1984-01-01

Structure and correlation functions are used to describe atmospheric variability during the 10-11 April day of AVE-SESAME 1979 that coincided with the Red River Valley tornado outbreak. The special mesoscale rawinsonde data are employed in calculations involving temperature, geopotential height, horizontal wind speed and mixing ratio. Functional analyses are performed in both the lower and upper troposphere for the composite 24 h experiment period and at individual 3 h observation times. Results show that mesoscale features are prominent during the composite period. Fields of mixing ratio and horizontal wind speed exhibit the greatest amounts of small-scale variance, whereas temperature and geopotential height contain the least. Results for the nine individual times show that small-scale variance is greatest during the convective outbreak. The functions also are used to estimate random errors in the rawinsonde data. Finally, sensitivity analyses are presented to quantify confidence limits of the structure functions.

Factors associated with the number of lesions excised for each skin cancer: a study of primary care physicians in Queensland, Australia.

PubMed

Baade, Peter D; Youl, Philippa H; Janda, Monika; Whiteman, David C; Del Mar, Christopher B; Aitken, Joanne F

2008-11-01

To assess physician, patient, and skin lesion characteristics that affect the number of benign skin lesions excised by primary care physicians for each skin cancer. Prospective study collecting clinical, patient, and histopathologic details of excisions or biopsies of skin lesions by random samples of primary care physicians. Southeast Queensland involving traditional family medicine physicians (n = 104; response rate, 53.9%) and family medicine physicians working in 27 primary care skin cancer clinics (n = 50; response rate, 75.0%). Of 28 755 skin examinations recorded during the study, 11 403 skin lesions were excised or biopsied; 97.5% of the excised lesions had clinical and histologic diagnoses recorded. Number of lesions needed to excise or biopsy (NNE) for 1 melanoma (pigmented lesions only) and NNE for 1 nonmelanoma skin cancer (nonpigmented lesions only). The NNE for nonpigmented lesions (n = 8139) was 1.5 (95% confidence interval, 1.4-1.6) and for pigmented lesions (n = 2977) was 19.6 (16.2-22.9). The NNE estimates were up to 8 times lower if the physician thought the lesion was likely to be malignant and up to 2.5 times higher if there was strong patient pressure to excise. The NNE estimates varied by other physician-, patient-, and lesion-related variables. Clinical impressions of excised skin lesions were strongly associated with NNE estimates. By focusing on pigmented skin lesions and by addressing the physician- and patient-specific factors identified, the effectiveness of future training for primary care physicians in the clinical management of skin cancer could be improved.

Osteological histology of the Pan-Alcidae (Aves, Charadriiformes): correlates of wing-propelled diving and flightlessness.

PubMed

Smith, N Adam; Clarke, Julia A

2014-02-01

Although studies of osteological morphology, gross myology, myological histology, neuroanatomy, and wing-scaling have all documented anatomical modifications associated with wing-propelled diving, the osteohistological study of this highly derived method of locomotion has been limited to penguins. Herein we present the first osteohistological study of the derived forelimbs and hind limbs of wing-propelled diving Pan-Alcidae (Aves, Charadriiformes). In addition to detailing differences between wing-propelled diving charadriiforms and nondiving charadriiforms, microstructural modifications to the humeri, ulnae and femora of extinct flightless pan-alcids are contrasted with those of volant alcids. Histological thin-sections of four species of pan-alcids (Alca torda, †Alca grandis, †Pinguinus impennis, †Mancalla cedrosensis) and one outgroup charadriiform (Stercorarius longicaudus) were compared. The forelimb bones of wing-propelled diving charadriiforms were found to have significantly thicker (∼22%) cortical bone walls. Additionally, as in penguins, the forelimbs of flightless pan-alcids are found to be osteosclerotic. However, unlike the pattern documented in penguins that display thickened cortices in both forelimbs and hind limbs, the forelimb and hind limb elements of pan-alcids display contrasting microstructural morphologies with thickened forelimb cortices and relatively thinner femoral cortices. Additionally, the identification of medullary bone in the sampled †Pinguinus impennis specimen suggests that further osteohistological investigation could provide an answer to longstanding questions regarding sexual dimorphism of Great Auks. Finally, these results suggest that it is possible to discern volant from flightless wing-propelled divers from fragmentary fossil remains. Copyright © 2013 Wiley Periodicals, Inc.

Identification of Specialists and Abundance-Occupancy Relationships among Intestinal Bacteria of Aves, Mammalia, and Actinopterygii.

PubMed

Green, Hyatt C; Fisher, Jenny C; McLellan, Sandra L; Sogin, Mitchell L; Shanks, Orin C

2015-12-28

The coalescence of next-generation DNA sequencing methods, ecological perspectives, and bioinformatics analysis tools is rapidly advancing our understanding of the evolution and function of vertebrate-associated bacterial communities. Delineation of host-microbe associations has applied benefits ranging from clinical treatments to protecting our natural waters. Microbial communities follow some broad-scale patterns observed for macroorganisms, but it remains unclear how the specialization of intestinal vertebrate-associated communities to a particular host environment influences broad-scale patterns in microbial abundance and distribution. We analyzed the V6 region of 16S rRNA genes amplified from 106 fecal samples spanning Aves, Mammalia, and Actinopterygii (ray-finned fish). We investigated the interspecific abundance-occupancy relationship, where widespread taxa tend to be more abundant than narrowly distributed taxa, among operational taxonomic units (OTUs) within and among host species. In a separate analysis, we identified specialist OTUs that were highly abundant in a single host and rare in all other hosts by using a multinomial model without excluding undersampled OTUs a priori. We show that intestinal microbes in humans and other vertebrates display abundance-occupancy relationships, but because intestinal host-associated communities have undergone intense specialization, this trend is violated by a disproportionately large number of specialist taxa. Although it is difficult to distinguish the effects of dispersal limitations, host selection, historical contingency, and stochastic processes on community assembly, results suggest that intestinal bacteria can be shared among diverse hosts in ways that resemble the distribution of "free-living" bacteria in the extraintestinal environment. Copyright © 2016, American Society for Microbiology. All Rights Reserved.

[Reproductive activity of Chelonia mydas (Testudines: Cheloniidae) in Isla de Aves, Venezuela (2001-2008)].

PubMed

Vera, Vicente; Buitrago, Joaquín

2012-06-01

The second major nesting-site for green turtles in the Caribbean is Isla de Aves, an island protected as a wildlife refuge since 1972, located at 650km Northeast from La Guaira, Venezuela. In this island, the nesting population monitoring started in 1972 and in a more continuous way after 1978, when a Scientific-Naval Station was established and scientific observations started. Since historical data show that female captures had severely affected population levels in this island before 1978, this study aim to describe recent reproductive activities. For this, during the nesting seasons of 2001-2002 and 2005-2008, nesting females were measured and tagged using metal flipper tags. A total of 458 nights were sampled observing 5 154 female emergences, with a maximum of 53 in a single night. Non-observed emergences were calculated fitting the temporal distribution of observed emergences to a normal curve. Total emergences estimated varied from X=637.1+/-106.6 in 2001 to X =2 853+/-42.5 in 2008 (ANOVA F(6.5df)=60.37, p<0.0001). Internesting interval in the same season was estimated in X=10.71+/-1.32 days. Clutch frequency in a nesting season was calculated as X=1.71+/-1.6 times per female and season. Estimated number of nesting females per year varied from X=373+/-12.5 females in 2001 to X=l 669+/-56.1 females in 2008 (ANOVA F 55.6df)=89.42, p<0.0001); with a positive and significant trend (r=0.842, p=0.036). Results show that nesting females numbers are increasing. We suggest that the protection of the nesting area for more than 30 years, has contributed with this population increase.

JPRS Report, Near East and South Asia.

DTIC Science & Technology

1991-07-16

Mohana Ranga Rao was murdered, there was virtually to Tamil Nadu as Prime Minister and Opposition leader no Government in the State with Mr. Rama Rao ... Rao Saturday he had no objections to the government accused the TDP [Teluga Desam Party] leaders of viti- making public anything concerning his talks...Minister P. Chidambaram’s Rao and Mr. Upendra would be held responsible if demand that the minutes of the meeting Mr. Karu- violence erupted or anything

A new species of Procyrnea (Nematoda: Habronematidae) parasitic in Rhea pennata (Aves: Rheidae) from Patagonia, Argentina, with a key to species of the genus.

PubMed

Bagnato, E; Frixione, M; Digiani, M C; Cremonte, F

2017-07-31

Procyrnea choique n. sp. is described from the lesser rhea, Rhea pennata d´Orbigny (Aves: Rheidae), from the Protected Natural Area Península Valdés, Chubut province, Argentina. The new species resembles P. ficheuri, P. murrayi, P. excisiformis, P. dollfusi, P. haliasturi, P. anterovulvata, P. graculae, P. brevicaudata, P. uncinipenis, P. javaensis, P. ameerae, P. ornata, P. aegotheles, P. spiralis, P. ruschii and P. aptera, mainly in the absence of lateral alae; but differs from its congeners by having a left spicule without barbs, the position of the vulva which is post-equatorial, the absence of lateral ridges, absent median precloacal papilla, asymmetrical caudal alae, males more than 6 mm long, left spicule 1 mm long and spicule ratio 1:3. Our results extend the taxonomy of Procyrnea Chabaud, 1958 and comprise the first report of a habronematid from R. pennata. A key to species of Procyrnea is presented.

Fire management and woody invasive plants in oak ecosystems

Treesearch

Joanne. Rebbeck

2012-01-01

The use of prescribed fire to sustain oak forests has increased rapidly in the last decade as the threat of poor regeneration and increased dominance of shade tolerant or fire sensitive tree species grows. While prescribed fire can favor oak regeneration, it may also increase the invasion and expansion of nonnative invasive plant species (NNIS). Little is known about...

75 FR 51104 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-18

.... Blome Granitoid Pavement in Grand Forks Boundary Increase, Lewis Blvd between Conklin and Fenton Ave, Lewis Blvd between Fenton Ave and Seward Ave; Woodland Ave between S 4th and Grand Forks, 10000605...

Increasing Avermectin Production in Streptomyces avermitilis by Manipulating the Expression of a Novel TetR-Family Regulator and Its Target Gene Product.

PubMed

Liu, Wenshuai; Zhang, Qinling; Guo, Jia; Chen, Zhi; Li, Jilun; Wen, Ying

2015-08-01

Avermectins produced by Streptomyces avermitilis are commercially important anthelmintic agents. The detailed regulatory mechanisms of avermectin biosynthesis remain unclear. Here, we identified SAV3619, a TetR-family transcriptional regulator designated AveT, to be an activator for both avermectin production and morphological differentiation in S. avermitilis. AveT was shown to indirectly stimulate avermectin production by affecting transcription of the cluster-situated activator gene aveR. AveT directly repressed transcription of its own gene (aveT), adjacent gene pepD2 (sav_3620), sav_7490 (designated aveM), and sav_7491 by binding to an 18-bp perfect palindromic sequence (CGAAACGKTKYCGTTTCG, where K is T or G and Y is T or C and where the underlining indicates inverted repeats) within their promoter regions. aveM (which encodes a putative transmembrane efflux protein belonging to the major facilitator superfamily [MFS]), the important target gene of AveT, had a striking negative effect on avermectin production and morphological differentiation. Overexpression of aveT and deletion of aveM in wild-type and industrial strains of S. avermitilis led to clear increases in the levels of avermectin production. In vitro gel-shift assays suggested that C-5-O-B1, the late pathway precursor of avermectin B1, acts as an AveT ligand. Taken together, our findings indicate positive-feedback regulation of aveT expression and avermectin production by a late pathway intermediate and provide the basis for an efficient strategy to increase avermectin production in S. avermitilis by manipulation of AveT and its target gene product, AveM. Copyright © 2015, American Society for Microbiology. All Rights Reserved.

Structural setting and kinematics of Nubian fault system, SE Western Desert, Egypt: An example of multi-reactivated intraplate strike-slip faults

NASA Astrophysics Data System (ADS)

Sakran, Shawky; Said, Said Mohamed

2018-02-01

Detailed surface geological mapping and subsurface seismic interpretation have been integrated to unravel the structural style and kinematic history of the Nubian Fault System (NFS). The NFS consists of several E-W Principal Deformation Zones (PDZs) (e.g. Kalabsha fault). Each PDZ is defined by spectacular E-W, WNW and ENE dextral strike-slip faults, NNE sinistral strike-slip faults, NE to ENE folds, and NNW normal faults. Each fault zone has typical self-similar strike-slip architecture comprising multi-scale fault segments. Several multi-scale uplifts and basins were developed at the step-over zones between parallel strike-slip fault segments as a result of local extension or contraction. The NNE faults consist of right-stepping sinistral strike-slip fault segments (e.g. Sin El Kiddab fault). The NNE sinistral faults extend for long distances ranging from 30 to 100 kms and cut one or two E-W PDZs. Two nearly perpendicular strike-slip tectonic regimes are recognized in the NFS; an inactive E-W Late Cretaceous - Early Cenozoic dextral transpression and an active NNE sinistral shear.

Multicenter Analysis of Midterm Clinical Outcomes of Arthroscopic Labral Repair in the Hip: Minimum 5-Year Follow-up.

PubMed

Hevesi, Mario; Krych, Aaron J; Johnson, Nick R; Redmond, John M; Hartigan, David E; Levy, Bruce A; Domb, Benjamin G

2018-02-01

The technique of hip arthroscopic surgery is advancing and becoming more commonly performed. However, most current reported results are limited to short-term follow-up, and therefore, the durability of the procedure is largely unknown. To perform a multicenter analysis of mid-term clinical outcomes of arthroscopic hip labral repair and determine the risk factors for patient outcomes. Cohort study; Level of evidence, 3. Prospectively collected data of primary hip arthroscopic labral repair performed at 4 high-volume centers between 2008 and 2011 were reviewed retrospectively. Patients were assessed preoperatively and postoperatively with the visual analog scale (VAS), modified Harris Hip Score (mHHS), and Hip Outcome Score-Sports-Specific Subscale (HOS-SSS) at a minimum of 5 years' follow-up. Factors including age, body mass index (BMI), Tönnis grade, and cartilage grade were analyzed in relation to outcome scores, and revision rates were determined. Failure was defined as subsequent ipsilateral hip surgery, including revision arthroscopic surgery and open hip surgery. A total of 303 patients (101 male, 202 female) with a mean age of 32.0 years (range, 10.7-58.9 years) were followed for a mean of 5.7 years (range, 5.0-7.9 years). Patients achieved mean improvements in VAS of 3.5 points, mHHS of 20.1 points, and HOS-SSS of 29.3 points. Thirty-seven patients (12.2%) underwent revision arthroscopic surgery, and 12 (4.0%) underwent periacetabular osteotomy, resurfacing, or total hip arthroplasty during the study period. Patients with a BMI >30 kg/m 2 had a mean mHHS score 9.5 points lower and a mean HOS-SSS score 15.9 points lower than those with a BMI ≤30 kg/m 2 ( P < .01). Patients aged >35 years at surgery had a mean mHHS score 4.5 points lower and a HOS-SSS score 6.7 points lower than those aged ≤35 years ( P = .03). Patients with Tönnis grade 2 radiographs demonstrated a 12.5-point worse mHHS score ( P = .02) and a 23.0-point worse HOS-SSS score ( P < .01

Life cycle and fecundity analysis of Lutzomyia shannoni (Dyar) (Diptera: Psychodidae).

PubMed

Ferro, C; Cárdenas, E; Corredor, D; Morales, A; Munstermann, L E

1998-01-01

The life cycle of Lutzomyia shannoni (Dyar), was described for laboratory conditions with maximum daily temperature of 27-30 degree C, minimum daily temperatures of 22-27 degree C and relative humidity between 87-99%. Life cycle in each stage was as follows: egg 6-12 days (ave, 8.5 days); first stage larva 5-13 days (ave. 9.6 days); second stage larva 4-13 days (ave. 9.2 days); third stage larva 5-19 days (ave. 11.8 days); fourth stage larva 7-37 days (ave. 19.9 days); pupa 7-32 days (ave. 15.2 days). The life expectancy of adults ranged from 4 to 15 days (ave. 8.6 days). The entire egg to adult period ranged from 36 to 74 days (ave. 54.6 days). On average, each female oviposited 22.7 eggs; the average egg retention per female was 24.3 eggs.

Exploring the beliefs underlying attitudes to active voluntary euthanasia in a sample of Australian medical practitioners and nurses: a qualitative analysis.

PubMed

White, Katherine M; Wise, Susi E; Young, Ross McD; Hyde, Melissa K

A qualitative study explored beliefs about active voluntary euthanasia (AVE) in a sample (N = 18) of medical practitioners and nurses from Australia, where AVE is not currently legal. Four behaviors relating to AVE emerged during the interviews: requesting euthanasia for oneself, legalizing AVE, administering AVE to patients if it were legalized, and discussing AVE with patients if they request it. Using thematic analysis, interviews were analyzed for beliefs related to advantages and disadvantages of performing these AVE behaviors. Medical practitioners and nurses identified a number of similar benefits for performing the AVE-related behaviors, both for themselves personally and as health professionals. Benefits also included a consideration of the positive impact for patients, their families, and the health care system. Disadvantages across behaviors focused on the potential conflict between those parties involved in the decision making process, as well as conflict between one's own personal and professional values.

Comparative cophylogenetics of Australian phabine pigeons and doves (Aves: Columbidae) and their feather lice (Insecta: Phthiraptera)

USGS Publications Warehouse

Sweet, Andrew D.; Chesser, R. Terry; Johnson, Kevin P.

2017-01-01

Host–parasite coevolutionary histories can differ among multiple groups of parasites associated with the same group of hosts. For example, parasitic wing and body lice (Insecta: Phthiraptera) of New World pigeons and doves (Aves: Columbidae) differ in their cophylogenetic patterns, with body lice exhibiting higher phylogenetic congruence with their hosts than wing lice. In this study, we focus on the wing and body lice of Australian phabine pigeons and doves to determine whether the patterns in New World pigeons and doves are consistent with those of pigeons and doves from other regions. Using molecular sequence data for most phabine species and their lice, we estimated phylogenetic trees for all three groups (pigeons and doves, wing lice and body lice), and compared the phabine (host) tree with both parasite trees using multiple cophylogenetic methods. We found a pattern opposite to that found for New World pigeons and doves, with Australian wing lice showing congruence with their hosts, and body lice exhibiting a lack of congruence. There are no documented records of hippoboscid flies associated with Australian phabines, thus these lice may lack the opportunity to disperse among host species by attaching to hippoboscid flies (phoresis), which could explain these patterns. However, additional sampling for flies is needed to confirm this hypothesis. Large differences in body size among phabine pigeons and doves may also help to explain the congruence of the wing lice with their hosts. It may be more difficult for wing lice than body lice to switch among hosts that vary more dramatically in size. The results from this study highlight how host–parasite coevolutionary histories can vary by region, and how local factors can shape the relationship.

Neurovascular Network Explorer 1.0: a database of 2-photon single-vessel diameter measurements with MATLAB(®) graphical user interface.

PubMed

Sridhar, Vishnu B; Tian, Peifang; Dale, Anders M; Devor, Anna; Saisan, Payam A

2014-01-01

We present a database client software-Neurovascular Network Explorer 1.0 (NNE 1.0)-that uses MATLAB(®) based Graphical User Interface (GUI) for interaction with a database of 2-photon single-vessel diameter measurements from our previous publication (Tian et al., 2010). These data are of particular interest for modeling the hemodynamic response. NNE 1.0 is downloaded by the user and then runs either as a MATLAB script or as a standalone program on a Windows platform. The GUI allows browsing the database according to parameters specified by the user, simple manipulation and visualization of the retrieved records (such as averaging and peak-normalization), and export of the results. Further, we provide NNE 1.0 source code. With this source code, the user can database their own experimental results, given the appropriate data structure and naming conventions, and thus share their data in a user-friendly format with other investigators. NNE 1.0 provides an example of seamless and low-cost solution for sharing of experimental data by a regular size neuroscience laboratory and may serve as a general template, facilitating dissemination of biological results and accelerating data-driven modeling approaches.

STRUCTURAL CONTROLS OF THE EMERSON PASS GEOTHERMAL SYSTEM, NORTHWESTERN NEVADA: CHARACTERIZATION OF A "BLIND" SYSTEM

DOE Office of Scientific and Technical Information (OSTI.GOV)

Anderson, Ryan B; Faulds, James E

The Pyramid Lake area is favorable for geothermal development due to the tectonic setting of the region. The Walker Lane belt, a dextral shear zone that accommodates ~20% relative motion between the Pacific and North American plates, terminates northwestward in northeast California. NW-directed dextral shear is transferred to WNW extension accommodated by N-to -NNE striking normal faults of the Basin and Range. As a consequence, enhanced dilation occurs on favorably oriented faults generating high geothermal potential in the northwestern Great Basin. The NW-striking right-lateral Pyramid Lake fault, a major structure of the northern Walker Lane, terminates at the southern endmore » of Pyramid Lake and transfers strain to the NNE-striking down to the west Lake Range fault, resulting in high geothermal potential. Known geothermal systems in the area have not been developed due to cultural considerations of the Pyramid Lake Paiute Tribe. Therefore, exploration has been focused on discovering blind geothermal systems elsewhere on the reservation by identifying structurally favorable settings and indicators of past geothermal activity. One promising area is the northeast end of Pyramid Lake, where a broad left step between the west-dipping range-bounding faults of the Lake and Fox Ranges has led to the formation of a broad, faulted relay ramp. Furthermore, tufa mounds, mineralized veins, and altered Miocene rocks occur proximal to a thermal anomaly discovered by a 2-m shallow temperature survey at the north end of the step-over in Emerson Pass. Detailed geologic mapping has revealed a system of mainly NNE-striking down to the west normal faults. However, there are three notable exceptions to this generality, including 1) a prominent NW-striking apparent right-lateral fault, 2) a NW-striking down to the south fault which juxtaposes the base of the mid-Miocene Pyramid sequence against younger late Tertiary sedimentary rocks, and 3) a NNE-striking down to the east normal

Comparative cophylogenetics of Australian phabine pigeons and doves (Aves: Columbidae) and their feather lice (Insecta: Phthiraptera).

PubMed

Sweet, Andrew D; Chesser, R Terry; Johnson, Kevin P

2017-05-01

Host-parasite coevolutionary histories can differ among multiple groups of parasites associated with the same group of hosts. For example, parasitic wing and body lice (Insecta: Phthiraptera) of New World pigeons and doves (Aves: Columbidae) differ in their cophylogenetic patterns, with body lice exhibiting higher phylogenetic congruence with their hosts than wing lice. In this study, we focus on the wing and body lice of Australian phabine pigeons and doves to determine whether the patterns in New World pigeons and doves are consistent with those of pigeons and doves from other regions. Using molecular sequence data for most phabine species and their lice, we estimated phylogenetic trees for all three groups (pigeons and doves, wing lice and body lice), and compared the phabine (host) tree with both parasite trees using multiple cophylogenetic methods. We found a pattern opposite to that found for New World pigeons and doves, with Australian wing lice showing congruence with their hosts, and body lice exhibiting a lack of congruence. There are no documented records of hippoboscid flies associated with Australian phabines, thus these lice may lack the opportunity to disperse among host species by attaching to hippoboscid flies (phoresis), which could explain these patterns. However, additional sampling for flies is needed to confirm this hypothesis. Large differences in body size among phabine pigeons and doves may also help to explain the congruence of the wing lice with their hosts. It may be more difficult for wing lice than body lice to switch among hosts that vary more dramatically in size. The results from this study highlight how host-parasite coevolutionary histories can vary by region, and how local factors can shape the relationship. Copyright © 2017 Australian Society for Parasitology. All rights reserved.

Suppressing lossy-film-induced angular mismatches between reflectance and transmittance extrema: optimum optical designs of interlayers and AR coating for maximum transmittance into active layers of CIGS solar cells.

PubMed

Chang, Yin-Jung

2014-01-13

The investigation of optimum optical designs of interlayers and antireflection (AR) coating for achieving maximum average transmittance (T(ave)) into the CuIn(1-x)Ga(x)Se2 (CIGS) absorber of a typical CIGS solar cell through the suppression of lossy-film-induced angular mismatches is described. Simulated-annealing algorithm incorporated with rigorous electromagnetic transmission-line network approach is applied with criteria of minimum average reflectance (R(ave)) from the cell surface or maximum T(ave) into the CIGS absorber. In the presence of one MgF2 coating, difference in R(ave) associated with optimum designs based upon the two distinct criteria is only 0.3% under broadband and nearly omnidirectional incidence; however, their corresponding T(ave) values could be up to 14.34% apart. Significant T(ave) improvements associated with the maximum-T(ave)-based design are found mainly in the mid to longer wavelengths and are attributed to the largest suppression of lossy-film-induced angular mismatches over the entire CIGS absorption spectrum. Maximum-T(ave)-based designs with a MgF2 coating optimized under extreme deficiency of angular information is shown, as opposed to their minimum-R(ave)-based counterparts, to be highly robust to omnidirectional incidence.

Diet is a major factor governing the fecal butyrate-producing community structure across Mammalia, Aves and Reptilia

PubMed Central

Vital, Marius; Gao, Jiarong; Rizzo, Mike; Harrison, Tara; Tiedje, James M

2015-01-01

Butyrate-producing bacteria have an important role in maintaining host health. They are well studied in human and medically associated animal models; however, much less is known for other Vertebrata. We investigated the butyrate-producing community in hindgut-fermenting Mammalia (n=38), Aves (n=8) and Reptilia (n=8) using a gene-targeted pyrosequencing approach of the terminal genes of the main butyrate-synthesis pathways, namely butyryl-CoA:acetate CoA-transferase (but) and butyrate kinase (buk). Most animals exhibit high gene abundances, and clear diet-specific signatures were detected with but genes significantly enriched in omnivores and herbivores compared with carnivores. But dominated the butyrate-producing community in these two groups, whereas buk was more abundant in many carnivorous animals. Clustering of protein sequences (5% cutoff) of the combined communities (but and buk) placed carnivores apart from other diet groups, except for noncarnivorous Carnivora, which clustered together with carnivores. The majority of clusters (but: 5141 and buk: 2924) did not show close relation to any reference sequences from public databases (identity <90%) demonstrating a large ‘unknown diversity'. Each diet group had abundant signature taxa, where buk genes linked to Clostridium perfringens dominated in carnivores and but genes associated with Ruminococcaceae bacterium D16 were specific for herbivores and omnivores. Whereas 16S rRNA gene analysis showed similar overall patterns, it was unable to reveal communities at the same depth and resolution as the functional gene-targeted approach. This study demonstrates that butyrate producers are abundant across vertebrates exhibiting great functional redundancy and that diet is the primary determinant governing the composition of the butyrate-producing guild. PMID:25343515

Diet is a major factor governing the fecal butyrate-producing community structure across Mammalia, Aves and Reptilia.

PubMed

Vital, Marius; Gao, Jiarong; Rizzo, Mike; Harrison, Tara; Tiedje, James M

2015-03-17

Butyrate-producing bacteria have an important role in maintaining host health. They are well studied in human and medically associated animal models; however, much less is known for other Vertebrata. We investigated the butyrate-producing community in hindgut-fermenting Mammalia (n = 38), Aves (n = 8) and Reptilia (n = 8) using a gene-targeted pyrosequencing approach of the terminal genes of the main butyrate-synthesis pathways, namely butyryl-CoA:acetate CoA-transferase (but) and butyrate kinase (buk). Most animals exhibit high gene abundances, and clear diet-specific signatures were detected with but genes significantly enriched in omnivores and herbivores compared with carnivores. But dominated the butyrate-producing community in these two groups, whereas buk was more abundant in many carnivorous animals. Clustering of protein sequences (5% cutoff) of the combined communities (but and buk) placed carnivores apart from other diet groups, except for noncarnivorous Carnivora, which clustered together with carnivores. The majority of clusters (but: 5141 and buk: 2924) did not show close relation to any reference sequences from public databases (identity <90%) demonstrating a large 'unknown diversity'. Each diet group had abundant signature taxa, where buk genes linked to Clostridium perfringens dominated in carnivores and but genes associated with Ruminococcaceae bacterium D16 were specific for herbivores and omnivores. Whereas 16S rRNA gene analysis showed similar overall patterns, it was unable to reveal communities at the same depth and resolution as the functional gene-targeted approach. This study demonstrates that butyrate producers are abundant across vertebrates exhibiting great functional redundancy and that diet is the primary determinant governing the composition of the butyrate-producing guild.

Connecting Amazonian, Cerrado, and Atlantic Forest histories: Paraphyly, old divergences, and modern population dynamics in tyrant-manakins (Neopelma/Tyranneutes, Aves: Pipridae).

PubMed

Capurucho, João Marcos Guimarães; Ashley, Mary V; Ribas, Camila C; Bates, John M

2018-06-11

Several biogeographic hypotheses have been proposed to explain connections between Amazonian and Atlantic forest biotas. These hypotheses are related to the timing of the connections and their geographic patterns. We performed a phylogeographic investigation of Tyrant-manakins (Aves: Pipridae, Neopelma/Tyranneutes) which include species inhabiting the Amazon and Atlantic forests, as well as gallery forests of the Cerrado. Using DNA sequence data, we determined phylogenetic relationships, temporal and geographic patterns of diversification, and recent intraspecific population genetic patterns, relative to the history of these biomes. We found Neopelma to be a paraphyletic genus, as N. chrysolophum is sister to Neopelma + Tyranneutes, with an estimated divergence of approximately 18 Myrs BP, within the oldest estimated divergence times of other Amazonian and Atlantic forest avian taxa. Subsequent divergences in the group occurred from Mid Miocene to Early Pliocene and involved mainly the Amazonian species, with an expansion into and subsequent speciation in the Cerrado gallery forests by N. pallescens. We found additional structure within N. chrysocephalum and N. sulphureiventer. Analysis of recent population dynamics in N. chrysocephalum, N. sulphureiventer, and N. pallescens revealed recent demographic fluctuations and restrictions to gene flow related to environmental changes since the last glacial cycle. No genetic structure was detected across the Amazon River in N. pallescens. The tyrant-manakins represent an old historical connection between the Amazon and Atlantic Forest. Copyright © 2018. Published by Elsevier Inc.

Genomic Organization of Repetitive DNA in Woodpeckers (Aves, Piciformes): Implications for Karyotype and ZW Sex Chromosome Differentiation

PubMed Central

Kretschmer, Rafael; Bertocchi, Natasha Avila; Degrandi, Tiago Marafiga; de Oliveira, Edivaldo Herculano Corrêa; Cioffi, Marcelo de Bello; Garnero, Analía del Valle; Gunski, Ricardo José

2017-01-01

Birds are characterized by a low proportion of repetitive DNA in their genome when compared to other vertebrates. Among birds, species belonging to Piciformes order, such as woodpeckers, show a relatively higher amount of these sequences. The aim of this study was to analyze the distribution of different classes of repetitive DNA—including microsatellites, telomere sequences and 18S rDNA—in the karyotype of three Picidae species (Aves, Piciformes)—Colaptes melanochloros (2n = 84), Colaptes campestris (2n = 84) and Melanerpes candidus (2n = 64)–by means of fluorescence in situ hybridization. Clusters of 18S rDNA were found in one microchromosome pair in each of the three species, coinciding to a region of (CGG)10 sequence accumulation. Interstitial telomeric sequences were found in some macrochromosomes pairs, indicating possible regions of fusions, which can be related to variation of diploid number in the family. Only one, from the 11 different microsatellite sequences used, did not produce any signals. Both species of genus Colaptes showed a similar distribution of microsatellite sequences, with some difference when compared to M. candidus. Microsatellites were found preferentially in the centromeric and telomeric regions of micro and macrochromosomes. However, some sequences produced patterns of interstitial bands in the Z chromosome, which corresponds to the largest element of the karyotype in all three species. This was not observed in the W chromosome of Colaptes melanochloros, which is heterochromatic in most of its length, but was not hybridized by any of the sequences used. These results highlight the importance of microsatellite sequences in differentiation of sex chromosomes, and the accumulation of these sequences is probably responsible for the enlargement of the Z chromosome. PMID:28081238

Connect Global Positioning System RF Module

NASA Technical Reports Server (NTRS)

Franklin, Garth W.; Young, Lawrence E.; Ciminera, Michael A.; Tien, Jeffrey Y.; Gorelik, Jacob; Okihiro, Brian Bachman; Koelewyn, Cynthia L.

2012-01-01

The CoNNeCT Global Positioning System RF Module (GPSM) slice is part of the JPL CoNNeCT Software Defined Radio (SDR). CoNNeCT is the Communications, Navigation, and Net working reconfigurable Testbed project that is part of NASA's Space Communication and Nav igation (SCaN) Program. The CoNNeCT project is an experimental dem onstration that will lead to the advancement of SDRs and provide a path for new space communication and navigation systems for future NASA exploration missions. The JPL CoNNeCT SDR will be flying on the International Space Station (ISS) in 2012 in support of the SCaN CoNNeCT program. The GPSM is a radio-frequency sampler module (see Figure 1) that directly sub-harmonically samples the filtered GPS L-band signals at L1 (1575.42 MHz), L2 (1227.6 MHz), and L5 (1176.45 MHz). The JPL SDR receives GPS signals through a Dorne & Margolin antenna mounted onto a choke ring. The GPS signal is filtered against interference, amplified, split, and fed into three channels: L1, L2, and L5. In each of the L-band channels, there is a chain of bandpass filters and amplifiers, and the signal is fed through each of these channels to where the GPSM performs a one-bit analog-to-digital conversion (see Figure 2). The GPSM uses a sub-harmonic, single-bit L1, L2, and L5 sampler that samples at a clock rate of 38.656 MHz. The new capability is the down-conversion and sampling of the L5 signal when previous hardware did not provide this capability. The first GPS IIF Satellite was launched in 2010, providing the new L5 signal. With the JPL SDR flying on the ISS, it will be possible to demonstrate navigation solutions with 10-meter 3-D accuracy at 10-second intervals using a field-program mable gate array (FPGA)-based feedback loop running at 50 Hz. The GPS data bits will be decoded and used in the SDR. The GPSM will also allow other waveforms that are installed in the SDR to demonstrate various GNSS tracking techniques.

Correct Patterning of the Primitive Streak Requires the Anterior Visceral Endoderm

PubMed Central

Stuckey, Daniel W.; Di Gregorio, Aida; Clements, Melanie; Rodriguez, Tristan A.

2011-01-01

Anterior-posterior axis specification in the mouse requires signalling from a specialised extra-embryonic tissue called the anterior visceral endoderm (AVE). AVE precursors are induced at the distal tip of the embryo and move to the prospective anterior. Embryological and genetic analysis has demonstrated that the AVE is required for anterior patterning and for correctly positioning the site of primitive streak formation by inhibiting Nodal activity. We have carried out a genetic ablation of the Hex-expressing cells of the AVE (Hex-AVE) by knocking the Diphtheria toxin subunit A into the Hex locus in an inducible manner. Using this model we have identified that, in addition to its requirement in the anterior of the embryo, the Hex-AVE sub-population has a novel role between 5.5 and 6.5dpc in patterning the primitive streak. Embryos lacking the Hex-AVE display delayed initiation of primitive streak formation and miss-patterning of the anterior primitive streak. We demonstrate that in the absence of the Hex-AVE the restriction of Bmp2 expression to the proximal visceral endoderm is also defective and expression of Wnt3 and Nodal is not correctly restricted to the posterior epiblast. These results, coupled with the observation that reducing Nodal signalling in Hex-AVE ablated embryos increases the frequency of phenotypes observed, suggests that these primitive streak patterning defects are due to defective Nodal signalling. Together, our experiments demonstrate that the AVE is not only required for anterior patterning, but also that specific sub-populations of this tissue are required to pattern the posterior of the embryo. PMID:21445260

Surgical site infections in an abdominal surgical ward at Kosovo Teaching Hospital.

PubMed

Raka, Lul; Krasniqi, Avdyl; Hoxha, Faton; Musa, Ruustem; Mulliqi, Gjyle; Krasniqi, Selvete; Kurti, Arsim; Dervishaj, Antigona; Nuhiu, Beqir; Kelmendi, Baton; Limani, Dalip; Tolaj, Ilir

2007-12-01

Abdominal surgical site infections (SSI) cause substantial morbidity and mortality for patients undergoing operative procedures. We determined the incidence of and risk factors for SSI after abdominal surgery in the Department of Abdominal Surgery at the University Clinical Centre of Kosovo (UCCK). Prospective surveillance of patients undergoing abdominal surgery was performed between December 2005 and June 2006. CDC definitions were followed to detect SSI and study forms were based on Europe Link for Infection Control through Surveillance (HELICS) protocol. A total of 253 surgical interventions in 225 patients were evaluated. The median age of patients was 42 years and 55.1% of them were male. The overall incidence rate of SSI was 12%. Follow-up was achieved for 84.1% of the procedures. For patients with an SSI, the median duration of hospitalization was 9 days compared with 4 days for those without an SSI (p2, use of antibiotic prophylaxis and NNIS class of >2 were all significant at p < .001. The SSI rates for the NNIS System risk classes 0, 1 and 2-3 were 4.2%, 46.7% and 100%, respectively. SSI caused considerable morbidity among surgical patients in UCCK. Appropriate active surveillance and infection control measures should be introduced during preoperative, intra-operative, and postoperative care to reduce infection rates.

Surgical wound infection rates in Spain: data summary, January 1997 through June 2012.

PubMed

Díaz-Agero Pérez, Cristina; Robustillo Rodela, Ana; Pita López, María José; López Fresneña, Nieves; Monge Jodrá, Vicente

2014-05-01

The Indicadores Clínicos de Mejora Continua de la Calidad (INCLIMECC) program was established in Spain in 1997. INCLIMECC is a prospective system of health care-associated infection (HAI) surveillance that collects incidence data in surgical and intensive care unit patients. The protocol is based on the National Healthcare Safety Network (NHSN) surveillance system, formerly known as the National Nosocomial Infection Surveillance (NNIS) system, and uses standard infection definitions from the US Centers for Disease Control and Prevention. Each hospital takes part voluntarily and selects the units and surgical procedures to be surveyed. This report is a summary of the data collected between January 1997 and June 2012. A total of 370,015 patients were included, and the overall incidence of surgical wound infection (SWI) was 4.51%. SWI rates are provided by NHSN operating procedure category and NNIS risk index category. More than 27% of the patients received inadequate antibiotic prophylaxis, the main reason being unsuitable duration (57.05% of cases). Today, the INCLIMECC network includes 64 Spanish hospitals. We believe that an HAI surveillance system with trained personnel external to the surveyed unit is a key component not only in infection control and prevention, but also in a quality improvement system. Copyright © 2014. Published by Mosby, Inc.

Neurovascular Network Explorer 2.0: A Simple Tool for Exploring and Sharing a Database of Optogenetically-evoked Vasomotion in Mouse Cortex In Vivo.

PubMed

Uhlirova, Hana; Tian, Peifang; Kılıç, Kıvılcım; Thunemann, Martin; Sridhar, Vishnu B; Chmelik, Radim; Bartsch, Hauke; Dale, Anders M; Devor, Anna; Saisan, Payam A

2018-05-04

The importance of sharing experimental data in neuroscience grows with the amount and complexity of data acquired and various techniques used to obtain and process these data. However, the majority of experimental data, especially from individual studies of regular-sized laboratories never reach wider research community. A graphical user interface (GUI) engine called Neurovascular Network Explorer 2.0 (NNE 2.0) has been created as a tool for simple and low-cost sharing and exploring of vascular imaging data. NNE 2.0 interacts with a database containing optogenetically-evoked dilation/constriction time-courses of individual vessels measured in mice somatosensory cortex in vivo by 2-photon microscopy. NNE 2.0 enables selection and display of the time-courses based on different criteria (subject, branching order, cortical depth, vessel diameter, arteriolar tree) as well as simple mathematical manipulation (e.g. averaging, peak-normalization) and data export. It supports visualization of the vascular network in 3D and enables localization of the individual functional vessel diameter measurements within vascular trees. NNE 2.0, its source code, and the corresponding database are freely downloadable from UCSD Neurovascular Imaging Laboratory website 1 . The source code can be utilized by the users to explore the associated database or as a template for databasing and sharing their own experimental results provided the appropriate format.

Engineered antibodies for monitoring of polynuclear aromatic hydrocarbons

DOE Office of Scientific and Technical Information (OSTI.GOV)

Karu, A.E.; Roberts, V.A.; Li, Q.X.

1998-06-01

'The long-term goal of this project is to develop antibodies and antibody-based methods for detection and recovery of polynuclear aromatic hydrocarbons (PAHs) and PAH adducts that are potential biomarkers in environmental and biological samples. The inherent cross-reactivity will be exploited by pattern recognition methods. Dr. Karu''s laboratory uses new haptens representing key PAHs to derive recombinant Fab (rFab) and single-chain Fv (scFv) antibodies from hybridoma lines and combinatorial phage display libraries. Computational models of the haptens and combining sites made by Dr. Roberts''s group are used to guide antibody engineering by mutagenesis. Dr. Li''s laboratory develops enzyme immunoassays (EIAs), sensors,more » and immunoaffinity methods that make use of the novel haptens and antibodies for practical analytical applications in support of DOE''s mission. This report summarizes work completed in one and one-half years of a 3-year project, with close collaboration between the three research groups. Dr. Alexander Karu''s laboratory: the authors proceeded with the two strategies described in the original proposal. Site-directed mutagenesis was used to correct differences in the rFab N-terminal amino acids that were introduced by the degenerate PCR primers used for gene amplification. The binding constants of the rFabs with the corrected sequences will be compared with those of the parent MAbs, and should be very similar. The 4D5 and 10C10 heavy and light chain sequences are being moved to the pCOMB3H phagemid vector to facilitate selection of new engineered mutants.'« less

HIGH RATES OF EVOLUTION PRECEDED THE ORIGIN OF BIRDS

PubMed Central

Puttick, Mark N; Thomas, Gavin H; Benton, Michael J; Polly, P David

2014-01-01

The origin of birds (Aves) is one of the great evolutionary transitions. Fossils show that many unique morphological features of modern birds, such as feathers, reduction in body size, and the semilunate carpal, long preceded the origin of clade Aves, but some may be unique to Aves, such as relative elongation of the forelimb. We study the evolution of body size and forelimb length across the phylogeny of coelurosaurian theropods and Mesozoic Aves. Using recently developed phylogenetic comparative methods, we find an increase in rates of body size and body size dependent forelimb evolution leading to small body size relative to forelimb length in Paraves, the wider clade comprising Aves and Deinonychosauria. The high evolutionary rates arose primarily from a reduction in body size, as there were no increased rates of forelimb evolution. In line with a recent study, we find evidence that Aves appear to have a unique relationship between body size and forelimb dimensions. Traits associated with Aves evolved before their origin, at high rates, and support the notion that numerous lineages of paravians were experimenting with different modes of flight through the Late Jurassic and Early Cretaceous. PMID:24471891

Diversity of Quill Mites of the Family Syringophilidae (Acari: Prostigmata) Parasitizing Owls (Aves: Strigiformes) With Remarks on the Host-Parasite Relationships.

PubMed

Skoracki, Maciej; Unsoeld, Markus; Marciniak, Natalia; Sikora, Bozena

2016-07-01

The quill mite fauna of the family Syringophilidae (Acari: Prostigmata: Cheyletoidea) associated with owls (Aves: Strigiformes) is reviewed. A new genus is proposed, Neobubophilus Skoracki & Unsoeld gen. nov. It differs from closely related Bubophilus (Bubophilus Philips and Norton, 1978) by the absence of leg setae vsII in the both sexes. In addition, four new species are described: (1) Neobubophilus cunicularius Skoracki & Unsoeld sp. nov. from Athene cunicularia (Molina, 1782) (Strigidae) from Paraguay; (2) Neobubophilus atheneus Skoracki & Unsoeld sp. nov. from Athene noctua (Scopoli, 1769) and Athene brama (Temminck, 1821) (Strigidae), both from India; (3) Bubophilus tytonus Skoracki & Unsoeld sp. nov. from Tyto alba affinis (Blyth, 1862) (Tytonidae) from Cameroon, and (4) Megasyringophilus dalmas Skoracki & Unsoeld sp. nov. from Megascops choliba (Vieillot, 1817) (Strigidae) from Venezuela. The following new host species are given: Bubo bubo (Linnaeus, 1758) (Strigidae) from Nepal for Bubophilus ascalaphus (Philips and Norton 1978) and Strix woodfordii (Smith, 1834) (Strigidae) from Tanzania for Bubophilus aluconis (aluconis Nattress and Skoracki 2009). A key for syringophilid genera and species associated with owls is constructed. The host-parasite relationships of syringophilid mites and owls are discussed. © The Authors 2016. Published by Oxford University Press on behalf of Entomological Society of America. All rights reserved. For Permissions, please email: journals.permissions@oup.com Version of Record, first published online May 24, 2016 with fixed content and layout in compliance with Art. 8.1.3.2 ICZN.

Inventory of File gdas1.t06z.sfluxgrbf06.grib2

Science.gov Websites

hour ave Visible Diffuse Downward Solar Flux [W/m^2] 036 surface NBDSF 0-6 hour ave Near IR Beam Downward Solar Flux [W/m^2] 037 surface NDDSF 0-6 hour ave Near IR Diffuse Downward Solar Flux [W/m^2] 038

Inventory of File gfs.t06z.sfluxgrbf06.grib2

Science.gov Websites

hour ave Visible Diffuse Downward Solar Flux [W/m^2] 036 surface NBDSF 0-6 hour ave Near IR Beam Downward Solar Flux [W/m^2] 037 surface NDDSF 0-6 hour ave Near IR Diffuse Downward Solar Flux [W/m^2] 038

40 CFR 725.60 - Withdrawal of submission by the submitter.

Code of Federal Regulations, 2012 CFR

2012-07-01

..., OPPT Document Control Office (DCO), EPA East Bldg., 1201 Constitution Ave., NW., Rm. 6428, Washington... Control Office (DCO), EPA East Bldg., 1201 Constitution Ave., NW., Rm. 6428, Washington, DC 20004. (ii... Document Control Office (DCO), EPA East Bldg., 1201 Constitution Ave., NW., Rm. 6428, Washington, DC 20004...

Monitoring bird population trends in North America

USGS Publications Warehouse

Robbins, C.S.; Bystrak, D.; Geissler, P.H.; Purroy, F.J.

1983-01-01

Se ofrece un nuevo metodo para computar las oscilaciones demograficas de las aves a lo largo de los anos. Con los datos suministrados por el proyecto 'Aves nidificantes en Norteamerica' , se indican en la Tabla 1 las pautas de cambio numerico de una serie seleccionada de aves holarticas.

78 FR 53194 - Advisory Group to the Internal Revenue Service Tax Exempt and Government Entities Division (TE/GE...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-28

..., Acting Designated Federal Officer, TE/GE Communications and Liaison; 1111 Constitution Ave. NW.; SE:T:CL... Constitution Ave. NW.; Room 3313; Washington, DC. Issues to be discussed relate to Employee Plans, Exempt... clearance. Photo identification must be presented. Please use the main entrance at 1111 Constitution Ave. NW...

Karyotype morphology suggests that the Nyctibius griseus (Gmelin, 1789) carries an ancestral ZW-chromosome pair to the order Caprimulgiformes (Aves)

PubMed Central

Nieto, Leonardo Martin; Kretschmer, Rafael; Ledesma, Mario Angel; Garnero, Analía Del Valle; Gunski, Ricardo José

2012-01-01

Abstract Studies of karyotypes have been revealing important information on the taxonomic relationships and evolutionary patterns in various groups of birds. However, the order Caprimulgiformes is one of the least known in terms of its cytotaxonomy. So far, there are no cytogenetic data in the literature on birds belonging to 3 of 5 families of this order -Nyctibiidae, Steatornithidae and Aegothelidae. For this reason, the aim of our study was to describe the karyotype of Nyctibius griseus (Gmelin, 1789) (Aves, Nyctibiidae, Caprimulgiformes) and contribute with new data that could help to clarify the evolutionary relationships in this group. Bone marrow was cultured directly to obtain material for the chromosome study. C-banding was used to visualize the constitutive heterochromatin and Ag-NOR-banding to reveal nucleolus organizer regions. The diploid number observed was 2n=86±. Using sequential Giemsa/C-banding staining, we determined that the W chromosome was entirely C-band positive with the two most prominent markers in the interstitial and distal regions of the long arm. The nucleolus organizer regions showed a typical location in a pair of microchromosomes that exhibited Ag-NOR.The results obtained for Nyctibius griseus suggest that, of all the species studied in the references cited, it has the most ancestral sex chromosome composition of the order Caprimulgiformes. PMID:24260678

Access to primary health care for acute vascular events in rural low income settings: a mixed methods study.

PubMed

Ahmed, Shyfuddin; Chowdhury, Muhammad Ashique Haider; Khan, Md Alfazal; Huq, Nafisa Lira; Naheed, Aliya

2017-01-18

Cardiovascular diseases (CVDs) are the leading cause of global mortality. Among the CVDs, acute vascular events (AVE) mainly ischemic heart diseases and stroke are the largest contributors. To achieve 25% reduction in preventable deaths from CVDs by 2025, health systems need to be equipped with extended service coverage in order to provide person-centered care. The overall goal of this proposed study is to assess access to health care in-terms of service availability, care seeking patterns and barriers to access care after AVE in rural Bangladesh. We will consider myocardial infarction (MI) and stroke as acute vascular events. We will conduct a mixed methods study in rural Matlab, Bangladesh. This study will comprise of a) health facility survey, b) structured questionnaire interview and c) qualitative study. We will assess service availabilities by creating an inventory of public and private health facilities. Readiness of the facilities to deliver services for AVE will be assessed through a health facility survey using 'service availability and readiness assessment' (SARA) tools of the World Health Organization (WHO). We will interview survivors of AVE and caregivers (present and accompanied the person during the event) of person who died from AVE for exploring patterns of care seeking during an AVE. For exploring barriers to access care for AVE, we will conduct in-depth interview with survivors of AVE and caregivers of the person who died from AVE. We will also conduct key informant interviews with the service providers at primary health care (PHC) facilities and government high level officials at central health administration of Bangladesh. This study will provide a comprehensive picture of access to primary health care services during acute cardiovascular events as stroke & MI in rural context of Bangladesh. It will explore available service facilities in rural area for management, utilization of services and barriers to access care during an acute emergency

Lake Shore Drive\\\\Grand Ave.\\\\E. Illinois Ave., May 2016, Lindsay Light Radiological Survey

EPA Pesticide Factsheets

Field gamma measurements process did not exceed the instrument threshold. Unshielded readings ranged from a minimumof 4,600 cpm to a maximum of 14,200 cpm unshielded and shielded readings ranged from a minimum of1,800 cpm to 2,680 cpm.

Seabrook Lock Complex, Lake Pontchartrain, Louisiana, Design for Wave Protection at Lock Entrance. Hydraulic Model Investigation.

DTIC Science & Technology

1980-05-01

281 °-3o4O) and NNE (110-340)] also transmit partial energy to waves from NW and N, respectively, these boundary directions (WNW and NNE) were...O~ O* C C C CO L CD0 ’d N C CC C U)P zWI in U) pU) C-j- 0 CD C ) 0 ) aL U) U’ 0 0 0 U) (L -~~k V )~LAU- 00 w C. z LI W w. z w z Li. 0-’ . 0 0 3 W Li

77 FR 70810 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-27

... District, Roughly bounded by Cecil B. Moore Ave., N. 10th, W. Oxford, N. 11th, W. Stiles, W. Flora & N... Courthouse Historic District (Boundary Increase), Temple Ave. N. & S., 1st Ave. E. & W., 2nd St. S., 1st St. N., Fayette, 12001020 Marengo County Demopolis Historic District (Boundary Increase), E. Gaines, N...

Fade Analysis of ORCA DATA Beam at NTTR and Pax River

DTIC Science & Technology

2010-08-01

bit-error-rate (BER) of the data beam on the downlink path. 15 Start Time-PST (Duration) Range Scin Index 1 Rx=5.1cm... Scin Index 2 Rx=13.7cm Scin Index 3 Rx=27.2cm Path Ave Cn2 (m-2/3) Path Ave Inner Scale Path Ave Outer Scale Flight 2 May 16

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Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-27

..., Director, TE/GE Communications and Liaison; 1111 Constitution Ave., NW.; SE:T:CL--Penn Bldg; Washington, DC..., June 15, 2011, from 9:30 a.m. to 12:30 p.m., at the Internal Revenue Service; 1111 Constitution Ave... at 1111 Constitution Ave., NW., to enter the building. Should you wish the ACT to consider a written...

BOLIVAR: the Caribbean-South America plate boundary between 60W and 71W as imaged by seismic reflection data

NASA Astrophysics Data System (ADS)

Magnani, M.; Mann, P.; Clark, S. A.; Escalona, A.; Zelt, C. A.; Christeson, G. L.; Levander, A.

2007-12-01

We present the results of ~6000km of marine multi-channel seismic (MCS) reflection data collected offshore Venezuela as part of the Broadband Ocean Land Investigation of Venezuela and the Antilles arc Region project (BOLIVAR). The imaged area spans almost 12 degrees of longitude and 5 degrees of latitude and encompasses the diffuse plate boundary between South America (SA) and the SE Caribbean plate (CAR). This plate boundary has been evolving for at least the past 55My when the volcanic island arc that borders the CAR plate started colliding obliquely with the SA continent: the collision front has migrated from west to east. BOLIVAR MCS data show that the crustal architecture of the present plate boundary is dominated by the eastward motion of the Caribbean plate with respect to SA and is characterized by a complex combination of convergent and strike-slip tectonics. To the north, the reflection data image the South Caribbean Deformed Belt (SCDB) and the structures related to the thrusting of the CAR plate under the Leeward Antilles volcanic arc region. The data show that the CAR underthrusting continues as far east as the southern edge of the Aves ridge and detailed stratigraphic dating of the Venezuela basin and trench deposits suggests that the collision began in the Paleogene. The amount of shortening along the SCDB decreases toward the east, in part due to the geometry of plate motion vectors and in part as a result of the NNE escape of the Maracaibo block in western Venezuela. South of the SCDB the MCS profiles cross the Leeward Antilles island arc and Cenozoic sedimentary basins, revealing a complex history of Paleogene-Neogene multiphase extension, compression, and tectonic inversion, as well as the influence of the tectonic activity along the right-lateral El Pilar - San Sebastian fault system. East of the Bonaire basin the MCS data image the southern end of the Aves Ridge abandoned volcanic island arc and the southwestern termination of the Grenada basin

Tomato immune receptor Ve1 recognizes effector of multiple fungal pathogens uncovered by genome and RNA sequencing

PubMed Central

de Jonge, Ronnie; Peter van Esse, H.; Maruthachalam, Karunakaran; Bolton, Melvin D.; Santhanam, Parthasarathy; Saber, Mojtaba Keykha; Zhang, Zhao; Usami, Toshiyuki; Lievens, Bart; Subbarao, Krishna V.; Thomma, Bart P. H. J.

2012-01-01

Fungal plant pathogens secrete effector molecules to establish disease on their hosts, and plants in turn use immune receptors to try to intercept these effectors. The tomato immune receptor Ve1 governs resistance to race 1 strains of the soil-borne vascular wilt fungi Verticillium dahliae and Verticillium albo-atrum, but the corresponding Verticillium effector remained unknown thus far. By high-throughput population genome sequencing, a single 50-Kb sequence stretch was identified that only occurs in race 1 strains, and subsequent transcriptome sequencing of Verticillium-infected Nicotiana benthamiana plants revealed only a single highly expressed ORF in this region, designated Ave1 (for Avirulence on Ve1 tomato). Functional analyses confirmed that Ave1 activates Ve1-mediated resistance and demonstrated that Ave1 markedly contributes to fungal virulence, not only on tomato but also on Arabidopsis. Interestingly, Ave1 is homologous to a widespread family of plant natriuretic peptides. Besides plants, homologous proteins were only found in the bacterial plant pathogen Xanthomonas axonopodis and the plant pathogenic fungi Colletotrichum higginsianum, Cercospora beticola, and Fusarium oxysporum f. sp. lycopersici. The distribution of Ave1 homologs, coincident with the presence of Ave1 within a flexible genomic region, strongly suggests that Verticillium acquired Ave1 from plants through horizontal gene transfer. Remarkably, by transient expression we show that also the Ave1 homologs from F. oxysporum and C. beticola can activate Ve1-mediated resistance. In line with this observation, Ve1 was found to mediate resistance toward F. oxysporum in tomato, showing that this immune receptor is involved in resistance against multiple fungal pathogens. PMID:22416119

Vegetative compatibility groups partition variation in the virulence of Verticillium dahliae on strawberry

PubMed Central

Fan, Rong; Cockerton, Helen M.; Armitage, Andrew D.; Bates, Helen; Cascant-Lopez, Emma; Antanaviciute, Laima; Xu, Xiangming; Hu, Xiaoping

2018-01-01

Verticillium dahliae infection of strawberry (Fragaria x ananassa) is a major cause of disease-induced wilting in soil-grown strawberries across the world. To understand what components of the pathogen are affecting disease expression, the presence of the known effector VdAve1 was screened in a sample of Verticillium dahliae isolates. Isolates from strawberry were found to contain VdAve1 and were divided into two major clades, based upon their vegetative compatibility groups (VCG); no UK strawberry isolates contained VdAve1. VC clade was strongly related to their virulence levels. VdAve1-containing isolates pathogenic on strawberry were found in both clades, in contrast to some recently published findings. On strawberry, VdAve1-containing isolates had significantly higher virulence during early infection, which diminished in significance as the infection progressed. Transformation of a virulent non-VdAve1 containing isolate, with VdAve1 was found neither to increase nor decrease virulence when inoculated on a susceptible strawberry cultivar. There are therefore virulence factors that are epistatic to VdAve1 and potentially multiple independent routes to high virulence on strawberry in V. dahliae lineages. Genome sequencing a subset of isolates across the two VCGs revealed that isolates were differentiated at the whole genome level and contained multiple changes in putative effector content, indicating that different clonal VCGs may have evolved different strategies for infecting strawberry, leading to different virulence levels in pathogenicity tests. It is therefore important to consider both clonal lineage and effector complement as the adaptive potential of each lineage will differ, even if they contain the same race determining effector. PMID:29451893

Vegetative compatibility groups partition variation in the virulence of Verticillium dahliae on strawberry.

PubMed

Fan, Rong; Cockerton, Helen M; Armitage, Andrew D; Bates, Helen; Cascant-Lopez, Emma; Antanaviciute, Laima; Xu, Xiangming; Hu, Xiaoping; Harrison, Richard J

2018-01-01

Verticillium dahliae infection of strawberry (Fragaria x ananassa) is a major cause of disease-induced wilting in soil-grown strawberries across the world. To understand what components of the pathogen are affecting disease expression, the presence of the known effector VdAve1 was screened in a sample of Verticillium dahliae isolates. Isolates from strawberry were found to contain VdAve1 and were divided into two major clades, based upon their vegetative compatibility groups (VCG); no UK strawberry isolates contained VdAve1. VC clade was strongly related to their virulence levels. VdAve1-containing isolates pathogenic on strawberry were found in both clades, in contrast to some recently published findings. On strawberry, VdAve1-containing isolates had significantly higher virulence during early infection, which diminished in significance as the infection progressed. Transformation of a virulent non-VdAve1 containing isolate, with VdAve1 was found neither to increase nor decrease virulence when inoculated on a susceptible strawberry cultivar. There are therefore virulence factors that are epistatic to VdAve1 and potentially multiple independent routes to high virulence on strawberry in V. dahliae lineages. Genome sequencing a subset of isolates across the two VCGs revealed that isolates were differentiated at the whole genome level and contained multiple changes in putative effector content, indicating that different clonal VCGs may have evolved different strategies for infecting strawberry, leading to different virulence levels in pathogenicity tests. It is therefore important to consider both clonal lineage and effector complement as the adaptive potential of each lineage will differ, even if they contain the same race determining effector.

Energy analysis of convectively induced wind perturbations

NASA Technical Reports Server (NTRS)

Fuelberg, Henry E.; Buechler, Dennis E.

1989-01-01

Budgets of divergent and rotational components of kinetic energy (KD and KR) are examined for four upper level wind speed maxima that develop during the fourth Atmospheric Variability Experiment (AVE IV) and the first AVE-Severe Environmental Storms and Mesoscale Experiment (AVE-SESAME I). A similar budget analysis is performed for a low-level jet stream during AVE-SESAME I. The energetics of the four upper level speed maxima is found to have several similarities. The dominant source of KD is cross-contour flow by the divergent wind, and KD provides a major source of KR via a conversion process. Conversion from available potential energy provides an additional source of KR in three of the cases. Horizontal maps reveal that the conversions involving KD are maximized in regions poleward of the convection. Low-level jet development during AVE-SESAME I appears to be assisted by convective activity to the west.

Use of RADARSAT-1 satellite imagery and geophysical data for oil and kimberlite exploration

NASA Astrophysics Data System (ADS)

Paganelli, Flora

The synergy of RADARSAT-1 and seismic imagery interpretation has been applied in the Blackstone area of the Central Alberta Foothills in the Canadian Cordillera thrust and fold belt to map the continuity of geological structures, which are of importance for oil and gas exploration. The reconstruction of the continuity of thrust-fold related major structures known in the area has been successful. Transverse faults and lineaments with ENE-WSW, NE-SW, and NNE-SSW trends have been delineated on the radar images. The ENE-WSW transverse faults have an extensional character, cut across the inner and outer Foothills and are persistent at the regional scale. The NE-SW and NNE-SSW transverse faults are wrench type faults, which are mainly localized in the inner Foothills. These structures have been identified for the first time in the area and are possibly a third generation fault-play type for oil and gas exploration. Principal Component Analysis (PCA) of RADARSAT-1 images was applied in the Buffalo Head Hills area, in the Western Canada Sedimentary Basin (WCSB), to provide an enhanced image base for structural mapping. North- and NNE-trending lineaments bounding the eastern edge of the Buffalo Head Hills along the Loon River valley, a conjugate set of NW- and NE-trending lineaments, and ENE-trending lineaments identifying the latest features in the area were outlined. The development of these structures has been related to Precambrian terrane assemblage in the WCSB during the Early Proterozoic, the development of the Peace River Arch, and the Laramide Orogeny. In the Buffalo Head Hills area a weights of evidence statistical approach was used to determine the spatial relationship of NNE-, NE-, -NW, and ENE-trending lineaments to known kimberlite locations. This method outlined different degrees of spatial correlation between kimberlites and lineaments, with higher correlations defined for the NNE, NE, and ENE lineament datasets. A weights of evidence model was then

77 FR 74510 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-14

...., Troy, 12001132 Westchester County Downtown Ossining Historic District (Boundary Increase), Main St., Central & Croton Aves., Ossining, 12001133 TEXAS Walker County Austin Hall, 1741 University Ave...

Prospective study of etoposide scheduling in combination chemotherapy for limited disease small cell lung carcinoma.

PubMed

Abratt, R P; Willcox, P A; de Groot, M; Goodman, H T; Jansen, E R; Salton, D G

1991-01-01

78 patients with limited disease small cell lung carcinoma (SCLC) were entered into a prospective randomised study of two combination regimens (AVE-5 and AVE-1) that differed only in the scheduling of etoposide. Patients in the AVE-5 arm received etoposide intravenously 60 mg/m2 on day 1 and orally 120 mg/m2 on days 2-5 of each cycle. Patients in the AVE-1 arm received etoposide 300 mg/m2 intravenously on day 1. Patients in both arms received doxorubicin and vincristine on day 1 of each cycle. The complete (53% vs. 26%) and the overall (75% vs. 52%) response rates were significantly higher in the AVE-5 arm. Median survival was also increased from 11 to 14 months in this arm. Toxicity was low and similar in both groups. The daily administration of etoposide in low toxicity combination therapy for SCLC is important. This can be conveniently achieved by using etoposide orally.

78 FR 14356 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-05

... SW. Marconi Ave., Portland, 13000119 RHODE ISLAND Providence County Edgewood Historic District--Shaw Plat, (Edgewood Neighborhood, Cranston, R.I. MPS) Shaw & Marion Aves., parts of Narragansett Blvd...

76 FR 54428 - Call for Applications for the International Buyer Program Calendar Year 2013

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-01

..., International Trade Administration, U.S. Department of Commerce, Ronald Reagan Building, 1300 Pennsylvania Ave... Commerce, 1300 Pennsylvania Ave., Ronald Reagan Building, Suite 800M-- Mezzanine Level--Atrium North...

76 FR 34099 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-10

... Recreation Center, 1361 Dr. Martin Luther King, Jr. Ave., Mobile, 11000407 International Longshoreman's Association Hall, 505 Dr. Martin Luther King, Jr. Ave., Mobile, 11000408 KANSAS Butler County Yingling...

Development of a surgical site infection (SSI) surveillance system, calculation of SSI rates and specification of important factors affecting SSI in a digestive organ surgical department.

PubMed

Kimura, Koji; Sawa, Akihiro; Akagi, Shinji; Kihira, Kenji

2007-06-01

We have developed an original system to conduct surgical site infection (SSI) surveillance. This system accumulates SSI surveillance information based on the National Nosocomial Infections Surveillance (NNIS) System and the Japanese Nosocomial Infections Surveillance (JNIS) System. The features of this system are as follows: easy input of data, high generality, data accuracy, SSI rate by operative procedure and risk index category (RIC) can be promptly calculated and compared with the current NNIS SSI rate, and the SSI rates and accumulated data can be exported electronically. Using this system, we monitored 798 patients in 24 operative procedure categories in the Digestive Organs Surgery Department of Mazda Hospital, Mazda Motor Corporation, from January 2004 through December 2005. The total number and rate of SSI were 47 and 5.89%, respectively. The SSI rates of 777 patients were calculated based on 15 operative procedure categories and Risk Index Categories (RIC). The highest SSI rate was observed in the rectum surgery of RIC 1 (30%), followed by the colon surgery of RIC3 (28.57%). About 30% of the isolated infecting bacteria were Enterococcus faecalis, Staphylococcus aureus, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Escherichia coli. Using quantification theory type 2, the American Society of Anesthesiology score (4.531), volume of hemorrhage under operation (3.075), wound classification (1.76), operation time (1.352), and history of diabetes (0.989) increased to higher ranks as factors for SSI. Therefore, we evaluated this system as a useful tool in safety control for operative procedures.

Seafloor morphology related to recent tectonics in the Alboran Sea Basin

NASA Astrophysics Data System (ADS)

Vázquez, Juan-Tomás; Estrada, Ferran; Vegas, Ramon; Ercilla, Gemma; Medialdea, Teresa; d'Acremont, Elia; Alonso, Belen; Fernández-Salas, Luis-Miguel; Gómez-Ballesteros, María; Somoza, Luis; Bárcenas, Patricia; Palomino, Desirée; Gorini, Christian

2014-05-01

A detailed geomorphological study of the northern part of the Alboran Sea Basin has been realized based on the combined analysis of multibeam swath bathymetric data and medium to very high resolution seismic profiles (singled Sparker, Airgun, TOPAS and Atlas PARASOUND P35). This has enabled us to define several tectonic-related seafloor features and their role in the recent tectonics. The observed morpho-tectonic features correspond to: i) lineal scarps with a wide range of dimensions and following several trends ,WNW-ESE, NE-SW, NNE-SSW and N-S; ii) NE-SW to NNE-SSW-oriented compressive ridges; iii) ENE-WSW to NE-SW-striking antiforms; iv) NNE-SSW-oriented lineal depressions; v) rhomb-shaped depressions; vi) lineal valleys, canyons and gullies with WNW-ESE, and N-S orientations; and vii) N-S directed dissected valleys, canyons and gullies. Three families of faults and related folds, with NE-SW, WNW-ESE and NNE-SSW to N-S have been interpreted within this geomorphological scheme. The NE-SW family corresponds to: a) major scarps in both flanks of the Alboran Ridge and b) the offshore prolongation of La Serrata Fault, and both have been considered as a set of sinistral strike-slip faults. To this family, some compressive ridges, antiforms and occasionally reverse faults have been correlated. The WNW-ESE family corresponds to a set of faulted valleys (occasionally with rhomb-shaped depressions), fault scarps and linear inflection points occurring in the northern Alboran margin and the Yusuf-Habibas corridor. This family has been interpreted as transtensive dextral strike-slip faults. The NNE-SSW to N-S family corresponds to a penetrative system of linear fault scarps and tectonic depressions that cross-cut the Alboran Ridge and the Djibouti-Motril marginal plateau. This family can be considered as more recent since it offsets the other two families and shows a minor importance with regard to the main reliefs. This communication is a contribution to the Spanish R + D

Water Permeability Adjusts Resorption in Lung Epithelia to Increased Apical Surface Liquid Volumes.

PubMed

Schmidt, Hanna; Michel, Christiane; Braubach, Peter; Fauler, Michael; Neubauer, Daniel; Thompson, Kristin E; Frick, Manfred; Mizaikoff, Boris; Dietl, Paul; Wittekindt, Oliver H

2017-03-01

The apical surface liquid (ASL) layer covers the airways and forms a first line of defense against pathogens. Maintenance of ASL volume by airway epithelia is essential for maintaining lung function. The proteolytic activation of epithelial Na + channels is believed to be the dominating mechanism to cope with increases in ASL volumes. Alternative mechanisms, in particular increases in epithelial osmotic water permeability (P osm ), have so far been regarded as rather less important. However, most studies mainly addressed immediate effects upon apical volume expansion (AVE) and increases in ASL. This study addresses the response of lung epithelia to long-term AVE. NCI-H441 cells and primary human tracheal epithelial cells, both cultivated in air-liquid interface conditions, were used as models for the lung epithelium. AVE was established by adding isotonic solution to the apical surface of differentiated lung epithelia, and time course of ASL volume restoration was assessed by the deuterium oxide dilution method. Concomitant ion transport was investigated in Ussing chambers. We identified a low resorptive state immediately after AVE, which coincided with proteolytic ion transport activation within 10-15 minutes after AVE. The main clearance of excess ASL occurred during a delayed (hours after AVE) high resorptive state, which did not correlate with ion transport activation. Instead, high resorptive state onset coincided with an increase in P osm , which depended on aquaporin up-regulation. In summary, our data demonstrate that, aside from ion transport activation, modulation of P osm is a major mechanism to compensate for long-term AVE in lung epithelia.

International R&M/Safety Cooperation Lessons Learned Between NASA and JAXA

NASA Technical Reports Server (NTRS)

Fernandez, Rene; Havenhill, Maria T.; Zampino, Edward J.; Kiefer, Dwayne E.

2013-01-01

Presented are a number of important experiences gained and lessons learned from the collaboration of the National Aeronautics and Space Administration (NASA) and the Japanese Aerospace Exploration Agency (JAXA) on the CoNNeCT (Communications, Navigation, and Networking re-Configurable Testbed) project. Both space agencies worked on the CoNNeCT Project to design, assemble, test, integrate, and launch a communications testbed facility mounted onto the International Space Station (ISS) truss. At the 2012 RAMS, two papers about CoNNeCT were presented: one on Ground Support Equipment Reliability & System Safety, and the other one on combined application of System Safety & Reliability for the flight system. In addition to the logistics challenges present when two organizations are on the opposite side of the world, there is also a language barrier. The language barrier encompasses not only the different alphabet, it encompasses the social interactions; these were addressed by techniques presented in the paper. The differences in interpretation and application of Spaceflight Requirements will be discussed in this paper. Although many, but definitely not all, of JAXA's Spaceflight Requirements were inspired by NASA, there were significant and critically important differences in how they were interpreted and applied. This paper intends to summarize which practices worked and which did not for an international collaborative effort so that future missions may benefit from our experiences. The CoNNeCT flight system has been successfully assembled, integrated, tested, shipped, launched and installed on the ISS without incident. This demonstrates that the steps taken to facilitate international understanding, communication, and coordination were successful and warrant discussion as lessons learned.

76 FR 8378 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-14

... MPS) 114 Carlisle Boulevard SE, Albuquerque, 11000032 NEW YORK Rensselaer County Chapel and Cultural Center, 2125 Burdett Ave, Troy, 11000041 Tompkins County Telluride House, 217 West Ave, Ithaca, 11000042...

75 FR 36442 - Notice of Availability of Record of Decision for the Canyons of the Ancients National Monument...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-25

... Lands Center, 15 Burnett Court, Durango, Colorado 81301 Dolores Public Library, 420 Railroad Ave... 81324 Durango Public Library, 1188 E. 2nd Ave., Durango, Colorado 81301 Interested persons may also...

77 FR 9960 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-21

.... Nehalem St., Clatskanie, 12000078 Douglas County Oregon State Soldier's Home Hospital, 1624 W. Harvard Ave... Forest Ave., 205-221 Lewis St., Vermillion, 12000086 WASHINGTON Pierce County Curran, Charles and Mary...

78 FR 20642 - Notice of Proposed CERCLA Agreement and Order on Consent for Removal Action by Bona Fide...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-05

... Fernando Valley Area 2 Superfund Site, Glendale Chromium Operable Unit, 264 W. Spazier Ave., Burbank... Site, Glendale Chromium Operable Unit, located at 264 W. Spazier Ave., Burbank, California. Under the...

Professed religious affiliation and the practice of euthanasia.

PubMed

Baume, P; O'Malley, E; Bauman, A

1995-02-01

Attitudes towards active voluntary euthanasia (AVE) and physician-assisted suicide (PAS) among 1,238 doctors on the medical register of New South Wales varied significantly with self-identified religious affiliation. More doctors without formal religious affiliation ('non-theists') were sympathetic to AVE, and acknowledged that they had practised AVE, than were doctors who gave any religious affiliation ('theists'). Of those identifying with a religion, those who reported a Protestant affiliation were intermediate in their attitudes and practices between the agnostic/atheist and the Catholic groups. Catholics recorded attitudes most opposed to AVE, but even so, 18 per cent of Catholic medical respondents who had been so requested, recorded that they had taken active steps to bring about the death of patients.

Environmental Assessment Anti-Terrorism/Force Protection Travis Air Force Base, California

DTIC Science & Technology

2003-09-01

Forbes Street and De Ronde Drive 0630 to 0900 and 1145 to 1630 weekdays POV, school buses, school children and their parents 225 POV privately...03L North Gate- Vacaville Gate Air Base Pkwy. Ra gsi de St. Hangar Ave. Travis Ave. Bu rg an B lvd . Hickam Ave. Fi rs t S t. Broadway St. Ca nn on D...Facility Addition and Alteration to Life Support Shop Taxiway Lima Repairs Electrical, Utilities, and Supporting Infrastructure* Engine Storage Facility

78 FR 9771 - Notice of Opportunity for Public Comment on Surplus Property Release at Brunswick-Golden Isles...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-11

... address: Atlanta Airports District Office, Attn: Aimee A. McCormick, Program Manager, 1701 Columbia Ave... McCormick, Program Manager, Atlanta Airports District Office, 1701 Columbia Ave., Suite 2-260, Atlanta, GA...

77 FR 2756 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-19

... Laundry, 1730-1746 E. Douglas, Wichita, 11001081. Union National Bank Building, (African American..., Roughly bounded by Mary Ave., S. 14th St., Columbus Ave., & S. University Park Dr., Waco, 11001094. [FR...

Velcro on the slippery slope: the role of psychiatry in active voluntary euthanasia.

PubMed

Ryan, C J

1995-12-01

The aim of the paper is to determine the role that psychiatrists should play in legislation that establishes a right to active voluntary euthanasia (AVE). One version of the "slippery slope" argument, usually invoked against the legalisation of AVE, is recast as an argument for the introduction of strong safeguards in any future AVE legislation. The literature surrounding the prevalence of psychiatric illnesses in the terminally ill, physicians' ability to identify such illnesses and the aetiology of suicide in the terminally ill is examined. The strength of the slippery slope argument, combined with the poor ability of general physicians to diagnose psychiatric illness in the terminally ill, demands that any legislation allowing AVE should require a mandatory psychiatric review of the patient requesting euthanasia. Any legislation adopted that establishes a right to active voluntary euthanasia should include a mandatory psychiatric review of the person requesting euthanasia and a cooling off period before the request is acceded to. In addition, the discovery of a serious mental illness ought to disqualify the affected person from the right to AVE until that illness resolves.

21 CFR 203.12 - An appeal from an adverse decision by the district office.

Code of Federal Regulations, 2012 CFR

2012-04-01

..., 10903 New Hampshire Ave., Silver Spring, MD 20993-0002. An appeal from an adverse decision by the... and Research, Food and Drug Administration, 10903 New Hampshire Ave., Silver Spring, MD 20993-0002...

21 CFR 203.12 - An appeal from an adverse decision by the district office.

Code of Federal Regulations, 2013 CFR

2013-04-01

..., 10903 New Hampshire Ave., Silver Spring, MD 20993-0002. An appeal from an adverse decision by the... and Research, Food and Drug Administration, 10903 New Hampshire Ave., Silver Spring, MD 20993-0002...

21 CFR 203.12 - An appeal from an adverse decision by the district office.

Code of Federal Regulations, 2014 CFR

2014-04-01

..., 10903 New Hampshire Ave., Silver Spring, MD 20993-0002. An appeal from an adverse decision by the... and Research, Food and Drug Administration, 10903 New Hampshire Ave., Silver Spring, MD 20993-0002...

View SE of threestory steel and brick building. Part of ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

View SE of three-story steel and brick building. Part of large complex of buildings along Milwaukee Ave. (1920, 1950, & 1960 Milwaukee Ave. E) that is attached to the back of 1891 Trombly Ave. Openings on first floor are bricked up; second floor rectangular widows on the street facade are framed by an arched brick pattern. One brick course protrudes to form a cornice line between the second and third floors - 1900 East Milwaukee (Industrial Building), Detroit, Wayne County, MI

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fogg, P; Aland, T; West, M

Purpose: To investigate the effects of external surrogate and tumour motion by observing the reconstructed phases and AveCT in an Amplitude and Time based 4DCT. Methods: Based on patient motion studies, Cos6 and sinusoidal motions were simulated as external surrogate and tumour motions in a motion phantom. The diaphragm and tumour motions may or may not display the same waveform therefore the same and different waveforms were programmed into the phantom, scanned and reconstructed based on Amplitude and Time. The AveCT and phases were investigated with these different scenarios. The AveCT phantom images were also compared with CBCT phantom imagesmore » programmed with the same motions. Results: For the same surrogate and tumour sin motions, the phases (Amplitude and Time) and AveCT indicated similar motions based on the position of the BB at the slice and displayed contrast values respectively. For cos6 motions, due to the varied time the tumour spends at each position, the Amplitude and Time based phases differed. The AveCT images represented the actual tumour motions and the Time and Amplitude based phases were represented by the surrogate with varied times. Conclusion: Different external surrogate and tumour motions may result in different displayed image motions when observing the AveCT and reconstructed phases. During the 4DCT, the surrogate motion is readily available for observation of the amplitude and time of the diaphragm position. Following image reconstruction, the user may need to observe the AveCT in addition to the reconstructed phases to comprehend the time weightings of the tumour motion during the scan. This may also apply to 3D CBCT images where the displayed tumour position in the images is influenced by the long duration of the CBCT. Knowledge of the tumour motion represented by the greyscale of the AveCT may also assist in CBCT treatment beam verification matching.« less

Primerless Finishing Systems for the Corrosion Protection of Aluminum.

DTIC Science & Technology

1988-09-19

1 Attn: K. Silberger 208485S. Normandle Ave. Torrance, CA 90502 Center For Naval Analyses................................................. 1 4401 Font Ave P.O. Box 16268 Alexandria, VA 22302-0268 MWA~2 i40Ř 7b

75 FR 15724 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-30

... information from public review, we cannot guarantee that we will be able to do so. J. Paul Loether, Chief... Downtown Historic District, Parts of E. Lake Blvd., Ford Ave., Jackson Blvd., Pinson St., Wharton Ave...

75 FR 65362 - Oncologic Drugs Advisory Committee; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-22

... Hampshire Ave., Silver Spring, MD 20993-0002. Information regarding special accommodations due to a... Evaluation and Research, Food and Drug Administration, 10903 New Hampshire Ave., Bldg. 31, rm. 2417, Silver...) Soft Gelatin Capsules, [[Page 65363

Factors associated with the rejection of active euthanasia: a survey among the general public in Austria

PubMed Central

2013-01-01

Background In recent decades, the general public has become increasingly receptive toward a legislation that allows active voluntary euthanasia (AVE). The purpose of this study was to survey the current attitude towards AVE within the Austrian population and to identify explanatory factors in the areas of socio-demographics, personal experiences with care, and ideological orientation. A further objective was to examine differences depending on the type of problem formulation (abstract vs. situational) for the purpose of measuring attitude. Methods A representative cross-sectional study was conducted across the Austrian population. Data were acquired from 1,000 individuals aged 16 years and over based on telephone interviews (CATI). For the purpose of measuring attitude toward AVE, two different problem formulations (abstract vs. situational) were juxtaposed. Results The abstract question about active voluntary euthanasia was answered negatively by 28.8%, while 71.2% opted in favour of AVE or were undecided. Regression analyses showed rejection of AVE was positively correlated with number of adults and children in the household, experience with care of seriously ill persons, a conservative worldview, and level of education. Mean or high family income was associated with lower levels of rejection. No independent correlations were found for variables such as sex, age, political orientation, self-rated health, and experiences with care of terminally ill patients. Correlation for the situational problem formulation was weaker and included fewer predictors than for the abstract question. Conclusions Our results suggest that factors relating to an individual’s interpersonal living situation and his/her cognitive convictions might be important determinants of the attitude toward AVE. If and to the extent that personal care experience plays a role, it is rather associated with rejection than with acceptance of AVE. PMID:23826902

77 FR 64353 - [NPS-WASO-NRNHL-11378; 2200-3200-665

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-19

... Mars Downtown Commercial Historic District, Bounded by 2nd St. N, 2nd Ave. W., 1st St., S., & 1st Ave. E., Le Mars, 12000908 MISSOURI Butler County Williams--Gierth House, (Poplar Bluff MPS) 848 Vine St...

75 FR 41235 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-15

... information from public review, we cannot guarantee that we will be able to do so. J. Paul Loether, Chief... Ford Place Historic District, 110-175 N Oakland Ave; 450-465 Ford Place; 144 N Los Robles Ave, Pasadena...

Size distribution and roundness of clasts within pseudotachylytes of the Gangavalli Shear Zone, Salem, Tamil Nadu: An insight into its origin and tectonic significance

NASA Astrophysics Data System (ADS)

Behera, Bhuban Mohan; Thirukumaran, V.; Soni, Aishwaraya; Mishra, Prasanta Kumar; Biswal, Tapas Kumar

2017-06-01

Gangavalli (Brittle) Shear Zone (Fault) near Attur, Tamil Nadu exposes nearly 50 km long and 1-3 km wide NNE-SSW trending linear belt of cataclasites and pseudotachylyte produced on charnockites of the Southern Granulite Terrane. Pseudotachylytes, as well as the country rock, bear the evidence of conjugate strike slip shearing along NNE-SSW and NW-SE directions, suggesting an N-S compression. The Gangavalli Shear Zone represents the NNE-SSW fault of the conjugate system along which a right lateral shear has produced seismic slip motion giving rise to cataclasites and pseudotachylytes. Pseudotachylytes occur as veins of varying width extending from hairline fracture fills to tens of meters in length. They carry quartz as well as feldspar clasts with sizes of few mm in diameter; the clast sizes show a modified Power law distribution with finer ones (<1000 {\\upmu }m2) deviating from linearity. The shape of the clasts shows a high degree of roundness (>0.4) due to thermal decrepitation. In a large instance, devitrification has occurred producing albitic microlites that suggest the temperature of the pseudotachylyte melt was >1000^{circ }\\hbox {C}. Thus, pseudotachylyte veins act as a proxy to understand the genetic process involved in the evolution of the shear zone and its tectonic settings.

DNR Recorder's Office

Science.gov Websites

(Physical Location) 400 Willoughby Ave 3rd Floor Juneau, AK 99801 (907) 465-2514 (Fax) 465-3454 Anchorage AND PHYSICAL LOCATION Paula Bradley, Recorder Manager 550 West 7th Ave. Suite #108 Anchorage, AK 99501

Surgical site infections in an abdominal surgical ward at Kosovo Teaching Hospital.

PubMed

Raka, Lul; Krasniqi, Avdyl; Hoxha, Faton; Musa, Ruustem; Mulliqi, Gjyle; Krasniqi, Selvete; Kurti, Arsim; Dervishaj, Antigona; Nuhiu, Beqir; Kelmendi, Baton; Limani, Dalip; Tolaj, Ilir

2008-01-01

Abdominal surgical site infections (SSI) cause substantial morbidity and mortality for patients undergoing operative procedures. We determined the incidence of and risk factors for SSI after abdominal surgery in the Department of Abdominal Surgery at the University Clinical Centre of Kosovo (UCCK). Prospective surveillance of patients undergoing abdominal surgery was performed between December 2005 and June 2006. CDC definitions were followed to detect SSI and study forms were based on Europe Link for Infection Control through Surveillance (HELICS) protocol. A total of 253 surgical interventions in 225 patients were evaluated. The median age of patients was 42 years and 55.1% of them were male. The overall incidence rate of SSI was 12%. Follow-up was achieved for 84.1% of the procedures. For patients with an SSI, the median duration of hospitalization was 9 days compared with 4 days for those without an SSI (p < 0.001). Surgical procedures were classified as emergent in 53.3% of cases. Superficial incisional SSI was most common (55%). Clinical infections were culture positive in 40.7% of cases. Duration of operation, duration of preoperative stay, wound class, ASA score > 2, use of antibiotic prophylaxis and NNIS class of > 2 were all significant at p < .001. The SSI rates for the NNIS System risk classes 0, 1 and 2-3 were 4.2%, 46.7% and 100%, respectively. SSI caused considerable morbidity among surgical patients in UCCK. Appropriate active surveillance and infection control measures should be introduced during preoperative, intra-operative, and postoperative care to reduce infection rates.

Ventilator-associated pneumonia in a pediatric intensive care unit in Saudi Arabia: a 30-month prospective surveillance.

PubMed

Almuneef, Maha; Memish, Ziad A; Balkhy, Hanan H; Alalem, Hala; Abutaleb, Abdulrahman

2004-09-01

To describe the rate, risk factors, and outcome of ventilator-associated pneumonia (VAP) in pediatric patients. This prospective surveillance study of VAP among all patients receiving mechanical ventilation for 48 hours or more admitted to a pediatric intensive care unit (PICU) in Saudi Arabia from May 2000 to November 2002 used National Nosocomial Infections Surveillance (NNIS) System definitions. Three hundred sixty-one eligible patients were enrolled. Most were Saudi with a mean age of 28.6 months. Thirty-seven developed VAP. The mean VAP rate was 8.87 per 1,000 ventilation-days with a ventilation utilization rate of 47%. The mean duration of mechanical ventilation was 21 days for VAP patients and 10 days for non-VAP patients. The mean PICU stay was 34 days for VAP patients and 15 days for non-VAP patients. Among VAP patients, Pseudomonas aeruginosa was the most common organism, followed by Staphylococcus aureus. Other gram-negative organisms were also encountered. There was no significant difference between VAP and non-VAP patients regarding mortality rate. Witnessed aspiration, reintubation, prior antibiotic therapy, continuous enteral feeding, and bronchoscopy were associated with VAP. On multiple logistic regression analysis, only prior antibiotic therapy, continuous enteral feeding, and bronchoscopy were independent predictors of VAP. The mean VAP rate in this hospital was higher than that reported by NNIS System surveillance of PICUs. This study has established a benchmark for future studies of VAP in the pediatric intensive care population in Saudi Arabia. Additional studies from the region are necessary for comparison and development of preventive measures.

76 FR 37150 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-24

.../National Historic Landmarks Program. ALABAMA Randolph County Wadley Railroad Depot, Broad St. at NE. corner...) 5316 Ruskin Ave., St. Louis (Independent City), 11000445 Western Electric--Southwestern Bell Telephone... Ferry, 11000452 Westchester County Hartsdale Railroad Station, 1 E. Hartsdale Ave., Hartsdale, 11000453...

Near-surface air temperature lapse rates in Xinjiang, northwestern China

NASA Astrophysics Data System (ADS)

Du, Mingxia; Zhang, Mingjun; Wang, Shengjie; Zhu, Xiaofan; Che, Yanjun

2018-02-01

Lapse rates of near-surface (2 m) air temperature are important parameters in hydrologic and climate simulations, especially for the mountainous areas without enough in-situ observations. In Xinjiang, northwestern China, the elevations range from higher than 7000 m to lower than sea level, but the existing long-term meteorological measurements are limited and distributed unevenly. To calculate lapse rates in Xinjiang, the daily data of near-surface air temperature ( T min, T ave, and T max) were measured by automatic weather stations from 2012 to 2014. All the in situ observation stations were gridded into a network of 1.5° (latitude) by 1.5° (longitude), and the spatial distribution and the daily, monthly, seasonal variations of lapse rates for T min, T ave, and T max in Xinjiang are analyzed. The Urumqi River Basin has been considered as a case to study the influence of elevation, aspect, and the wet and dry air conditions to the T min, T ave, and T max lapse rates. Results show that (1) the lapse rates for T min, T ave, and T max vary spatially during the observation period. The spatial diversity of T min lapse rates is larger than that of T ave, and that of T max is the smallest. For each season, T max lapse rates have more negative values than T ave lapse rates which are steeper than T min lapse rates. The weakest spatial diversity usually appears in July throughout a year. (2) The comparison for the three subregions (North, Middle, and South region) exhibits that lapse rates have similar day-to-day and month-to-month characteristics which present shallower values in winter months and steeper values in summer months. The T ave lapse rates in North region are shallower than those in Middle and South region, and the steepest T ave lapse rates of the three regions all appear in April. T min lapse rates are shallower than T max lapse rates. The maximum medians of T min and T max lapse rates for each grid in the three regions all appear in January, whereas the

40 CFR 262.83 - Notification and consent.

Code of Federal Regulations, 2010 CFR

2010-07-01

... (CONTINUED) STANDARDS APPLICABLE TO GENERATORS OF HAZARDOUS WASTE Transfrontier Shipments of Hazardous Waste...), Environmental Protection Agency, 1200 Pennsylvania Ave., NW., Washington, DC 20460, with the words “Attention... (2254A), Environmental Protection Agency, 1200 Pennsylvania Ave., NW., Washington, DC 20460, with the...

75 FR 53640 - Call for Applications for the International Buyer Program Calendar Year 2012

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-01

..., International Trade Administration, U.S. Department of Commerce, Ronald Reagan Building, 1300 Pennsylvania Ave., Ronald Reagan Building, Suite 800M--Mezzanine Level--Atrium North, Washington, DC 20004. Telephone (202... Commerce, 1300 Pennsylvania Ave., Ronald Reagan Building, Suite 800M-- Mezzanine Level--Atrium North...

78 FR 6334 - Housing Choice Voucher Program; Office of Public and Indian Housing Announcement of Funding...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-30

... ALLEN HA 2301 JASMINE AVE, MC ALLEN, TX 80 336,384 78501. VA: ALEXANDRIA REDEV & HA 600 N FAIRFAX ST... ANTONIO, TX 0 19,600 78295. TX: MC ALLEN HA 2301 JASMINE AVE, MC ALLEN, TX 0 15,800 78501. VA: ALEXANDRIA...

A Comprehensive Seismic Characterization of the Cove Fort-Sulphurdale Geothermal Site, Utah

NASA Astrophysics Data System (ADS)

Zhang, H.; Li, J.; Zhang, X.; Liu, Y.; Kuleli, H. S.; Toksoz, M. N.

2012-12-01

tomography method of Zhang et al. (2007). For the study region, overall the velocity is lower and attenuation is higher in the western part. Correspondingly, the anisotropy is also stronger, indicating the fractures may be more developed in the western part. The average fast polarization directions of fast shear waves at each station mostly point NNE. From the focal mechanism analysis from selected events, it shows that the normal faulting events have strikes in NNE direction, and the events with strike slip mechanism have strikes either parallel with the NNE trending faults or their conjugate ones. Assuming the maximum horizontal stress (SHmax) is parallel with the strike of the normal faulting events and bisects the two fault planes of the strike-slip events, the inverted source mechanism suggests a NNE oriented maximum horizontal stress regime. This area is under W-E tensional stress, which means maximum compressional stress should be in the N-E or NNE direction in general. The combination of shear wave splitting and focal mechanism analysis suggests that in this region the faults and fractures are aligned in the NNE direction.

Ancient DNA analyses of early archaeological sites in New Zealand reveal extreme exploitation of moa (Aves: Dinornithiformes) at all life stages

NASA Astrophysics Data System (ADS)

Oskam, Charlotte L.; Allentoft, Morten E.; Walter, Richard; Scofield, R. Paul; Haile, James; Holdaway, Richard N.; Bunce, Michael; Jacomb, Chris

2012-10-01

The human colonisation of New Zealand in the late thirteenth century AD led to catastrophic impacts on the local biota and is among the most compelling examples of human over-exploitation of native fauna, including megafauna. Nearly half of the species in New Zealand' s pre-human avifauna are now extinct, including all nine species of large, flightless moa (Aves: Dinornithiformes). The abundance of moa in early archaeological sites demonstrates the significance of these megaherbivores in the diet of the first New Zealanders. Combining moa assemblage data, based on DNA identification of eggshell and bone, with morphological identification of bone (literature and museum catalogued specimens), we present the most comprehensive audit of moa to date from several significant 13th-15th century AD archaeological deposits across the east coast of the South Island. Mitochondrial DNA (mtDNA) was amplified from 251 of 323 (78%) eggshell fragments and 22 of 27 (88%) bone samples, and the analyses revealed the presence of four moa species: Anomalopteryx didiformis; Dinornis robustus; Emeus crassus and Euryapteryx curtus. The mtDNA, along with polymorphic microsatellite markers, enabled an estimate of the minimum number of individual eggs consumed at each site. Remarkably, in one deposit over 50 individual eggs were identified - a number that likely represents a considerable proportion of the total reproductive output of moa in the area and emphasises that human predation of all life stages of moa was intense. Molecular sexing was conducted on bones (n = 11). Contrary to previous ancient DNA studies from natural sites that consistently report an excess of female moa, we observed an excess of males (2.7:1), suggestive that males were preferential targets. This could be related to different behaviour between the two highly size-dimorphic sexes in moa. Lastly, we investigated the moa species from recovered skeletal and eggshell remains from seven Wairau Bar burials, and identified

75 FR 2117 - Privacy Act of 1974; System of Records

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-14

... Force, 30 Space Communications Squadron, Building 12000, Room 104, 867 Washington Ave., Suite 205... Wing Space Communications Squadron, 867 Washington Avenue, Suite 200-1, Vandenberg Air Force Base... Superintendent, 30 Space Wing Command Post 867 Washington Ave, Suite 205, Vandenberg Air Force Base, California...

76 FR 54250 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-31

... Architecture of Pasadena: Influence of the Arts and Crafts Movement MPS) 1330 Hillcrest Ave., Pasadena... OH 93, Ironton, 11000671 Lucas County Libbey, Edward Drummond, High School, 1250 Western Ave., Toledo, 11000672 PUERTO RICO Orocovis Municipality Cueva La Espiral, (Prehistoric Rock Art of Puerto Rico MPS...

75 FR 1060 - Draft Guidance for Industry on Planning for the Effects of High Absenteeism to Ensure...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-08

... Medically Necessary Drug Products; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice... Drug Evaluation and Research, Food and Drug Administration, 10903 New Hampshire Ave., Bldg. 51, rm... Evaluation and Research, Food and Drug Administration, 10903 New Hampshire Ave., WO Bldg. 51, rm. 3359...

75 FR 1809 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-13

... Ave., Bovill, 09001280. Cox Barn, (Agricultural Properties of Latah County, Idaho) 1290 American Ridge... Historic District, Main, N. & S. Center, John Sts. & Dutchess, Park, S. Maple & Elm Aves., Millerton...., Coventry and W. Greenwich, 09001290. Utah Salt Lake County Altadena Apartments, (Salt Lake City MPS) 310 S...

76 FR 12847 - Change of Address; Requests for Exemption From the Bar Code Label Requirements

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-09

... INFORMATION CONTACT: Rikin Mehta, Center for Drug Evaluation and Research, Food and Drug Administration, 10903... and Research, Food and Drug Administration, 10903 New Hampshire Ave., Bldg. 51, Silver Spring, MD... Evaluation and Research, Food and Drug Administration, 10903 New Hampshire Ave., Bldg. 51, Silver Spring, MD...

76 FR 32863 - Guidance for Industry and Investigators on Enforcement of Safety Reporting Requirements for...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-07

..., Center for Drug Evaluation and Research, Food and Drug Administration, 10903 New Hampshire Ave., Bldg. 51...-40), Center for Biologics Evaluation and Research, Food and Drug Administration, 1401 Rockville Pike..., Center for Drug Evaluation and Research, Food and Drug Administration, 10903 New Hampshire Ave., Bldg. 51...

21 CFR 807.37 - Inspection of establishment registration and device listings.

Code of Federal Regulations, 2012 CFR

2012-04-01

... Administration, Center for Devices and Radiological Health, Office of Compliance, 10903 New Hampshire Ave., Bldg... Drug Administration, Center for Devices and Radiological Health, Office of Compliance, 10903 New Hampshire Ave., Bldg. 66, rm. 3521, Silver Spring, MD 20993-0002. In addition, there will be available for...

77 FR 8885 - Draft Guidance for Industry on Biosimilars: Questions and Answers Regarding Implementation of the...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-15

... Evaluation and Research, Food and Drug Administration, 10903 New Hampshire Ave., Bldg. 51, Rm. 2201, Silver... Biologics Evaluation and Research, Food and Drug Administration, 1401 Rockville Pike, Suite 200N, Rockville... Drug Evaluation and Research, Food and Drug Administration, 10903 New Hampshire Ave., Bldg. 51, Rm...

78 FR 78366 - Draft Guidance for Industry on Naming of Drug Products Containing Salt Drug Substances; Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-26

... Evaluation and Research, Food and Drug Administration, 10903 New Hampshire Ave., Bldg. 51, Rm. 2201, Silver... for Drug Evaluation and Research, Food and Drug Administration, 10903 New Hampshire Ave., Silver... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2013-D-1566...

Insights into intermediate phases of human intestinal fluids visualized by atomic force microscopy and cryo-transmission electron microscopy ex vivo.

PubMed

Müllertz, Anette; Fatouros, Dimitrios G; Smith, James R; Vertzoni, Maria; Reppas, Christos

2012-02-06

The current work aims to study at the ultrastructural level the morphological development of colloidal intermediate phases of human intestinal fluids (HIFs) produced during lipid digestion. HIFs were aspirated near the ligament of Treitz early (30 min), Aspirate(early), and 1 h, Aspirate(1h)(ave,comp), after the administration of a heterogeneous liquid meal into the antrum. The composition of the sample aspirated 1 h after meal administration was similar to the average lumenal composition 1 h after meal administration (Aspirate(1h)(ave,comp)). The colloidal structures of individual aspirates and supernatants of aspirates after ultracentrifugation (micellar phase) were characterized by means of atomic force microscopy (AFM) and cryogenic transmission electron microscopy (Cryo-TEM). AFM revealed domain-like structures in Aspirate(early) and both vesicles and large aggregates Aspirate(1h)(ave,comp). Rough surfaces and domains varying in size were frequently present in the micellar phase of both Aspirate(early) and Aspirate(1h)(ave,comp). Cryo-TEM revealed an abundance of spherical micelles and occasionally presented worm-like micelles coexisting with faceted and less defined vesicles in Aspirate(early) and Aspirate(1h)(ave,comp). In Aspirate(1h)(ave,comp) oil droplets were visualized with bilayers closely located to their surface suggesting lipolytic product phases accumulated on the surface of the oil droplet. In the micellar phase of Aspirate(early), Cryo-TEM revealed the presence of spherical micelles, small vesicles, membrane fragments, oil droplets and plate-like structures. In the micellar phase of Aspirate(1h)(ave,comp) the only difference was the absence of oil droplets. Visualization studies previously performed with biorelevant media revealed structural features with many similarities as presented in the current investigation. The impression of the complexity and diversion of these phases has been reinforced with the excessive variation of structural

Using the chemical analysis of magnetite to constrain various stages in the formation and genesis of the Kiruna-type chadormalu magnetite-apatite deposit, Bafq district, Central Iran

NASA Astrophysics Data System (ADS)

Heidarian, Hassan; Lentz, David; Alirezaei, Saeed; Peighambari, Sima; Hall, Douglas

2016-12-01

Textural and compositional data are presented for different types of magnetite in the Chadormalu iron deposit to discern the genesis of various styles of mineralization. Samples were chosen according to their paragenetic relations to apatite and their host setting: magnetite-apatite veins in the altered host rocks, disseminated magnetite-apatite assemblages in the marginal parts of the main ore body, and massive magnetite associated with irregular apatite veinlets from internal part of the main ore body. Scanning electron microscopy - back scatter electron (SEM-BSE) images reveal that there are three main generations of magnetite in each of the different magnetite-apatite assemblages. Primary magnetite (Mag1) features abundant porosity and a dark appearance. A second generation of magnetite (Mag2) replacing Mag1 shows a lighter appearance with both sharp and gradational contacts with the primary magnetite crystals. The two magnetite types are related to dissolution-precipitation processes due to changing physico-chemical parameters of the ore fluids. A third type of magnetite (Mag3) with a recrystallized appearance and foam-like triple junctions was mostly observed in magnetite-apatite veins in the main ore body and in veins hosted by altered rocks. Electron probe microanalyses (EPMA) were utilized to discriminate the various magnetite generations in the different magnetite-apatite assemblages. Applying published elemental discrimination diagrams shows that most primary magnetites fall into the hydrothermal- and Kiruna-type fields. Primary magnetite contains lower FeO (88.77-93.65 wt.%; average 91.5 wt.%), and higher SiO2 (0.21-2.26 wt.%; ave. 0.32 wt.%), Al2O3 (0.001-0.45 wt.%; ave. 0.053 wt.%), and CaO (0.002-0.48 wt.%; ave. 0.078 wt.%) contents, which might be related to magmatically derived fluids. Secondary magnetites have higher FeO (89.23-93.49 wt.%; ave. 92.11 wt.%), lower SiO2 (0.037-0.189 wt.%; ave. 0.072 wt.%), Al2O3 (0.004-0.072 wt.%; ave. 0.019 wt

78 FR 54931 - Notice of Applications for Deregistration Under the Investment Company Act of 1940

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-06

... of Investment Management, Exemptive Applications Office, 100 F Street NE., Washington, DC 20549-8010... Address: c/o Morgan Stanley Investment Management Inc., 522 Fifth Ave., New York, NY 10036. Clarity Fund... Investment Management Inc., 522 Fifth Ave., New York, NY 10036. Mill City Ventures III, Ltd. [File No. 811...

40 CFR 262.56 - Annual reports.

Code of Federal Regulations, 2010 CFR

2010-07-01

... APPLICABLE TO GENERATORS OF HAZARDOUS WASTE Exports of Hazardous Waste § 262.56 Annual reports. (a) Primary...), Environmental Protection Agency, 1200 Pennsylvania Ave., NW., Washington, DC 20460. Hand-delivered reports... St. and Pennsylvania Ave., NW., Washington, DC 20004. [51 FR 28682, Aug. 8, 1986, as amended at 56 FR...

77 FR 27463 - Device Improvements for Pediatric X-Ray Imaging; Public Meeting; Request for Comments

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-10

... pediatric x-ray imaging that may benefit from standards development or further research. DATES: Date and... held at FDA White Oak Campus, 10903 New Hampshire Ave., Building 31 Conference Center, the Great Room..., Food and Drug Administration, 10903 New Hampshire Ave., Bldg. 66, rm. 4527, Silver Spring, MD 20993...

78 FR 77711 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-24

... Cook County Bush Temple of Music, 100 W. Chicago Ave., 800 N. Clark St., Chicago, 13001001 Stony Island Trust and Savings Bank Building, 6760 S. Stony Island Ave., Chicago, 13001002 Lake County Waukegan... Johnson County Sigma Pi Fraternity House, 108 McLean St., Iowa City, 13001019 Maryland Baltimore...

77 FR 20025 - Draft Guidance for Industry on Compliance Policy for Reporting Drug Sample Distribution...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-03

... Research, Food and Drug Administration, 10903 New Hampshire Ave., Bldg. 51, Rm. 2201, Silver Spring, MD... Evaluation and Research (CBER), Food and Drug Administration, 1401 Rockville Pike, Suite 200N, Rockville, MD... Research, Food and Drug Administration, 10903 New Hampshire Ave., Bldg. 51, Rm. 4288, Silver Spring, MD...

76 FR 36954 - Public Notice for Waiver of Aeronautical Land-Use Assurance; Shell Lake Municipal Airport, Shell...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-23

... at the Wisconsin Department of Transportation, 4802 Sheboygan Ave., Room 701, Madison, WI 53707. FOR... categorical exclusion for this land release action was prepared by Wisconsin Dept. of Transportation-Bureau of..., 7200 34th Ave. So., Suite B, Minneapolis, MN 55450; or at the Wisconsin Department of Transportation...

76 FR 53909 - Draft Guidance for Industry on Tablet Scoring: Nomenclature, Labeling, and Data for Evaluation...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-30

... your comment on this draft guidance before it begins work on the final version of the guidance, submit... Drug Evaluation and Research, Food and Drug Administration, 10903 New Hampshire Ave., Bldg. 51, rm... Drug Evaluation and Research, Food and Drug Administration, 10903 New Hampshire Ave., Bldg. 51, rm...

78 FR 44572 - Draft Guidance for Industry on Pre-Launch Activities Importation Requests; Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-24

..., Center for Drug Evaluation and Research, Food and Drug Administration, 10903 New Hampshire Ave., Bldg. 51..., Center for Drug Evaluation and Research, Food and Drug Administration, 10903 New Hampshire Ave., Bldg. 51... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2013-D-0836...

78 FR 2676 - Draft Guidance for Industry on Abuse-Deterrent Opioids-Evaluation and Labeling; Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-14

... Evaluation and Research, Food and Drug Administration, 10903 New Hampshire Ave., Bldg. 51, rm. 2201, Silver... Evaluation and Research (HFD-170), Food and Drug Administration, 10903 New Hampshire Ave., Bldg. 22, rm. 3160... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2013-D-0045...

Final Environmental Assessment for FY07-11 BRAC Construction Requirements at Andrews Air Force Base, Maryland

DTIC Science & Technology

2007-09-01

IO B LV D G S T AR KA N S AS R D FIRST ST AT LA N TA A... IO A VE C S T O A K ST SALEM RD K N ER R D R M AD IS O N D R STARKEY AVE TENNESSEE AVE PATRICK RD S. D AK O TA A VE TOPE KA ST VANDE NBERG...DR CHIC AGO DR TY LE R R D CELME R LN HALL CT WACO LN BUNKER HILL ST O P ER AT IO N S D R MAPL E CT SEATTLE AVE RE NO DR O R E G O N C IR AL

78 FR 45518 - Extension of a Currently Approved Information Collection for the Weatherization Assistance Program

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-29

... Weatherization Assistance Program AGENCY: U.S. Department of Energy. ACTION: Notice and request for comments... Platt Patrick, EE- 2K, U.S. Department of Energy, 1000 Independence Ave., SW., Washington, DC 20585... Hall, EE-2K, U.S. Department of Energy, 1000 Independence Ave., SW., Washington, DC 20585-1290, Phone...

78 FR 59660 - Extension of a Currently Approved Information Collection for the Weatherization Assistance Program

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-27

... Weatherization Assistance Program AGENCY: U.S. Department of Energy. ACTION: Notice and request for comments... Platt Patrick, EE- 2K, U.S. Department of Energy, 1000 Independence Ave. SW., Washington, DC 20585... Hall, EE-2K, U.S. Department of Energy, 1000 Independence Ave. SW., Washington, DC 20585-1290, Phone...

77 FR 29681 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-18

... District (Boundary Increase), Roughly bounded by W. 17th St., Dr. Martin Luther King Jr. Dr., Wright Ave... Monroe County Michelsen, George J. Furniture Factory, 182 Ave. D, Rochester, 12000328 New York County Hotel Albert, 23 E. 10th St., Manhattan, 12000329 OHIO Franklin County United States Post Office and...

75 FR 41517 - Notice of Availability of the Draft Environmental Impact Statement for the Proposed Over The RiverTM

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-16

... Macon Ave., Ca[ntilde]on City, Colorado; Salida Regional Library, 405 ``E'' Street, Salida, Colorado; Arkansas Headwaters Recreation Area (AHRA) office, 307 West Sackett Ave., Salida, Colorado; and the Denver... adjacent to the Arkansas River between the cities of Salida and Ca[ntilde]on City in Colorado. It has filed...

Structural geologic analysis of Nevada using ERTS-1 images: A preliminary report

NASA Technical Reports Server (NTRS)

Rowan, L. C.; Wetlaufer, P. H.

1973-01-01

Structural analysis of Nevada using ERTS-1 images showns several previously unrecognized lineaments which may be the surface manifestations of major fault or fracture zones. Principle trends are NE, NW, NNE-NNW, and ENE. Two lineament zones, the Walker Lane and Midas Trench lineament system, transect the predominantly NNE-NNW trending mountain ranges for more than 500 km. 50 circular features have been delineated. Comparison with known Tertiary volcanic centers and reference to geologic maps suggest 8 new centers. Preferred distribution of mines and Tertiary volcanic centers along some of the major lineament suggests a genetic relationship. The intersection of three previously unmapped lineaments in northwestern Nevada is the location of a highly productive metallogenic district. In the Walker Lane, ENE-trending lineament appear to be related to the occurrence of productive ore deposits.

Nakhon Phanom RTAFB, Thailand. Revised Uniform Summary of Surface Weather Observations (RUSSWO) Parts A-F

DTIC Science & Technology

1974-11-12

KNTS) 1 3 4. 6 7 - 10 11 16 17 21 22 . 27 28 33 34 -40 41 47 48 . 55 -56 % WIND DIR. SPEED N .4 .4 2.1. NNE 4iY, , 8 NE ,? , ,_ 2,3 ENE 1 1 ll 2,8__...KNTS) 1 .3 4.6 7 . 10 11 - 16 17 .21 22 .27 28 . 33 34- 40 41 -47 48 .55 ! 56 % WIND DIN. SPEED N 05O4 0 .4 4.6 NNE 4 .- ,h 2,. 8 N 6E Lou .3 1.3 2.8...1fl!o14o I CLAN HOURS (1 8 T. ) CONDITION SPEED MEAN (KNTS) 13 4. 6 7. 10 11 16 17. 21 22 27 28 .33 34 .40 41 •47 48 - 55 t56 % WINDDIN SPEED 1 .9

Avon Park Range, Avon Park, Florida. Revised Uniform Summary of Surface Weather Observations (RUSSWO)

DTIC Science & Technology

1979-05-02

L.S T. SPEED 1712MEAN (KNT$) 1 3 4 • 6 7 10 1 • 16 17 • 21 22 27 2 8 • 33 34 • 40 41 • 47 48 • 55 󈧼 % W IND DIR. SPEED _b a __,7 __9_ - 07 i 7.2...7.- 10 11.-16 17 .23 22.-27 28 .33 34.40 41.-47 48 .-55 ?:56 % WIND DIR. I I I I SPEED 1 4.5 1 2.’ j 6 ,5 2 8 NNE , _ u 3._ __ _ _ _ 5 - . 2.7 __NE___...3 4.6 7. 10 11.-16 117.211 22.-27 I28.-33 I34. 40 41 -47 48 .55 ? 56 % IWINO DIR. I_ I_ SPEED_ _ _ __ _ NNE 1~ L ZT1 _____ [ ____ .__4 8 1 5s6 N E j

The establishment of a statewide surveillance program for hospital-acquired infections in large Victorian public hospitals: a report from the VICNISS Coordinating Centre.

PubMed

Russo, Philip L; Bull, Ann; Bennett, Noleen; Boardman, Claire; Burrell, Simon; Motley, Jane; Berry, Kylie; Friedman, N Deborah; Richards, Michael

2006-09-01

A 1998 survey of acute Victorian public hospitals (VPH) revealed that surveillance of hospital-acquired infections (HAI) was underdeveloped, definitions and methodology varied considerably, and results disseminated inconsistently. The survey identified the need for an effective surveillance system for HAI. To develop and support a standardized surveillance program for HAIs in large acute VPH and to provide risk-adjusted, procedure-specific, HAI rates. In 2002, the independent Victorian Nosocomial Infection Surveillance System (VICNISS) Coordinating Centre (VCC) was established to develop and support the standardized surveillance program. A multidisciplinary team was recruited. A communication strategy, surveillance manual, user groups, and Web site were developed. Formal education sessions were provided to participating infection control nurse consultants (ICCs). Surveillance activities were based on the US Centers for Diseases Control and Prevention's National Nosocomial Infection Surveillance System (NNIS) surgical site infection and intensive care unit (ICU) components. NNIS methods were modified to suit local needs. Data collection was paper based or through existing hospital software. An advisory committee of key stakeholders met every second month. The surveillance program was rolled out over 12 months to all 28 large adult VPH. Data on over 20,000 surgical procedures performed at participating sites between November 11, 2002, and December 31, 2004, were submitted. Thirteen hospitals contributed to the ICU surveillance activities. Following aggregation and analysis by the VCC, hospital- and state-level results were posted on the Web page for hospitals to review. A standardized approach for surveillance of HAI was established in a short time frame in over 28 VPH. VICNISS is a tool that will continue to provide participating hospitals with a basis for continuous quality improvement.

Cretaceous combined structure in eastern Sichuan Basin, China

NASA Astrophysics Data System (ADS)

Wang, P.; Liu, S.

2009-12-01

Eastern Sichuan Basin is confined by two thin-skinned fold-thrust belt, NW-trending Southern Daba Shan (Shan=Mountain) (SDB) in the northeast and NNE- or NE-trending Western XueFeng Shan (WXF) in the southeast, which constitute two convergent salients convex to the inner basin respectively. Although many factors can lead to the formation of fold-thrust belt salients, the eastern Sichuan salients would be attributed to the combined structure (firstly nominated by Chinese geologist, Li Siguang), which means the interaction of two structural belts in the same period. By field surveying and geological map interpreting, we found that WXF deformation began in Late Jurassic along the eastern side of structral belt, where the synclines cored by Upper-Middle Jurassic rock. The initial time of SDB deformation remains poorly determined, however our palaeocurrent data of Lower Cretaceous rock in adjecent foreland basin indicate the provenance from northeast or east. Hence we considered the two fold-thrust belt started interactive in Late Jurassic and mainly combined during Cretaceous. In Early Cretaceous, the front belt of WXF salient arrived near KaiXian where NEE-trending arc-shape folds converged with the NWW-trending arc-shape folds of SDB.The two salients shaped like an westward "open mouth", east of which EW-trending folds of two structural belts juxtaposed. Particularly in the middle belt of WXF (FengJie - WuFeng) the earlier NEE-trending folds were refolded by later NNE-trending folds. We interpret the NEE-trending folds as the front belt of earlier (maybe Late Jurassic) WXF salient. When the two combined fold belts propagated westward together, the original NNE-trending front belt of WXF constrained by the front belt of SDB and formed the curved fold trend lines convex to NNW. Then as WXF deformation continued but SDB gradually terminated, the consequent NNE-trending folds could not be curved and would superpose on the earlier NEE-trending folds.In Late Cretaceous

Information Ubiquity in Austere Locations

DTIC Science & Technology

2011-01-01

are incompatible (e.g., GSM vs. CDMA ), or are insecure for one’s purposes. There might be satellite communi- cations, but its access might be...Ave. Latency (Unloaded) Ave. Latency (Overloaded) Std Dev. (Unloaded) Std Dev. (Overloaded) M ill is ec on ds AOI UAV UAV 1 UAV 2 UAV 3 Joseph

SpaceWire Tiger Team Findings and Suggestions

NASA Technical Reports Server (NTRS)

Ishac, Joseph A.

2011-01-01

This technical report intends to highlight the key findings and recommendations of the SpaceWire Tiger Team for the CoNNeCT project. It covers findings which are technical in nature, covering design concepts and approaches.

Fluid Intelligence Allows Flexible Recruitment of the Parieto-Frontal Network in Analogical Reasoning

PubMed Central

Preusse, Franziska; Elke, van der Meer; Deshpande, Gopikrishna; Krueger, Frank; Wartenburger, Isabell

2011-01-01

Fluid intelligence is the ability to think flexibly and to understand abstract relations. People with high fluid intelligence (hi-fluIQ) perform better in analogical reasoning tasks than people with average fluid intelligence (ave-fluIQ). Although previous neuroimaging studies reported involvement of parietal and frontal brain regions in geometric analogical reasoning (which is a prototypical task for fluid intelligence), however, neuroimaging findings on geometric analogical reasoning in hi-fluIQ are sparse. Furthermore, evidence on the relation between brain activation and intelligence while solving cognitive tasks is contradictory. The present study was designed to elucidate the cerebral correlates of geometric analogical reasoning in a sample of hi-fluIQ and ave-fluIQ high school students. We employed a geometric analogical reasoning task with graded levels of task difficulty and confirmed the involvement of the parieto-frontal network in solving this task. In addition to characterizing the brain regions involved in geometric analogical reasoning in hi-fluIQ and ave-fluIQ, we found that blood oxygenation level dependency (BOLD) signal changes were greater for hi-fluIQ than for ave-fluIQ in parietal brain regions. However, ave-fluIQ showed greater BOLD signal changes in the anterior cingulate cortex and medial frontal gyrus than hi-fluIQ. Thus, we showed that a similar network of brain regions is involved in geometric analogical reasoning in both groups. Interestingly, the relation between brain activation and intelligence is not mono-directional, but rather, it is specific for each brain region. The negative brain activation–intelligence relationship in frontal brain regions in hi-fluIQ goes along with a better behavioral performance and reflects a lower demand for executive monitoring compared to ave-fluIQ individuals. In conclusion, our data indicate that flexibly modulating the extent of regional cerebral activity is characteristic for fluid intelligence

Comparisons of Integrated Radiation Transport Models with Microdosimetry Data in Spaceflight

NASA Technical Reports Server (NTRS)

Cucinotta, Francis A.; Nikjoo, H.; Kim, M. Y.; Hu, X.; Dicello, J. F.; Pisacane, V. L.

2006-01-01

Astronauts are exposed to galactic cosmic rays (GCR), trapped protons, and possible solar particle events (SPE) during spaceflight. For such complicated mixtures of radiation types and kinetic energies, tissue equivalent proportional counters (TEPC's) represent a simple time-dependent approach for radiation monitoring. Of interest in radiation protection is the average quality factor of a radiation field defined as a function of linear energy transfer, LET, Q(sub ave)(LET). However TEPC's measure the average quality factors as a function of lineal energy (y), Q(sub ave)(y) defined as the average energy deposition in a volume divided by the average chord length of the volume. Lineal energy, y deviates from LET due to energy straggling, delta-ray escape or entry, and nuclear fragments produced in the detector. Using integrated space radiation models that includes the transport code HZETRN/BRYNTRN, the quantum nuclear interaction model, QMSFRG, and results from Monte-Carlo track simulations of TEPC's response to ions, we consider comparisons of model calculations to TEPC results from NASA missions in low Earth orbit and make predictions for lunar and Mars missions. Good agreement between the model and measured spectra from past NASA missions is found. A finding of this work is that TEPC's values for trapped or solar protons of Q(sub ave)(y) range from 1.9-2.5, overestimating Q(sub ave)(LET), which ranges from 1.4-1.6 with both quantities increasing with shielding depth due to nuclear secondaries Comparisons for the complete GCR spectra show that Q(sub ave)(LET) for GCR is approximately 3.5-4.5, while TEPC's measure 2.9-3.4 for Q(sub ave)(y) with the GCR values decreasing with depth as heavy ions are absorbed in shielding material. Our results support the use of TEPC's for space radiation environmental monitoring when computational analysis is used for proper data interpretation.

Proceedings of the Defense Nuclear Agency Conference on Arms Control and Verification Technology ACT Held in Williamsburg, Virginia on 1-4 June 1992

DTIC Science & Technology

1992-12-01

99352 Newington, VA 22122-9998 Steve Kigu Rick King Julia L. Klam NRL USAF IDA 45 Overlook Ave SW MS-4616 21A Eagan Ave. 1801 N. Beauregard St...ATTN: GARY RIPPLE ATTN: B STUPSKI JR ATTN: YANCEY PHILLIPS ATTN: C DIMAGGIO ATTN: C RUSSELL 21ST CENTURY INDUSTRIES ATTN: D BRANDWEIN ATTN: LEONARD M

11. VIEW OF ARROYO SECO CHANNEL SEEN FROM AVENUE 14 ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

11. VIEW OF ARROYO SECO CHANNEL SEEN FROM AVENUE 14 BRIDGE. SAN FERNANDO ROAD BRIDGE AT CENTER. LOOKING 25° NNE. - Arroyo Seco Parkway, Figueroa Street Viaduct, Spanning Los Angeles River, Los Angeles, Los Angeles County, CA

11. COULTERVILLE ROAD AT ROCK SLIDE AREA WITH HWY 140 ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

11. COULTERVILLE ROAD AT ROCK SLIDE AREA WITH HWY 140 AT REAR. LOOKING NNE. GIS: N-37 43 04.7 / W-119 43 00.3 - Coulterville Road, Between Foresta & All-Weather Highway, Yosemite Village, Mariposa County, CA

77 FR 6819 - Notice of Filing of Plats of Survey; Alaska

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-09

... No. 4615, Alaska, located within the Barrow Townsite, situated within Tps. 22 and 23 N., R. 18 W...: Bureau of Land Management, Alaska State Office; 222 W. 7th Ave., Stop 13; Anchorage, AK 99513-7599. FOR..., BLM-Alaska State Office; 222 W. 7th Ave., Stop 13; Anchorage, AK 99513-7599; Tel: 907-271-5481; fax...

Tropical Cyclone Wind Probability Forecasting (WINDP).

DTIC Science & Technology

1981-04-01

llq. h. ,c ilrac (t’ small probabilities (below 107c) is limited II(t’h, numb(r o!, significant digits given: therefore 1t( huld lU r~ruidvd as being...APPLIED SCI. CORP. ENGLAMD ;7MOS. SCIENCES OEPT., LIBRARY ATTN: LIBARY , SUITE 500 400 WASHINGTON AVE. 6811 KENILWORTH AVE. EUROPEAN CENTRE FOR MEDIUM

Project VALOR: Trajectories of Change in PTSD in Combat-Exposed Veterans

DTIC Science & Technology

2013-10-01

System Research Service (151B) 150 South Huntington Ave. Boston, MA 02130 REPORT DATE: October 2013 TYPE OF REPORT: Annual...Institute Inc. 150 South Huntington Ave Research 151B USAMRMC 9. SPONSORING / MONITORING AGENCY NAME(S) AND...trajectory subtypes by means of latent growth mixture modeling. The availability of comprehensive data on PTSD symptoms and related exposures and

Jointing patterns and tectonic evolution of the Maciço Calcário Estremenho, Lusitanian Basin, Portugal

NASA Astrophysics Data System (ADS)

Carvalho, Jorge M. F.

2018-05-01

The Maciço Calcário Estremenho (MCE) is an uplifted Jurassic limestone massif unit of the Lusitanian Basin, Portugal, where five main joint sets trending NNE-SSW, WSW-ENE, WNW-ESE, NW-SE, and NNW-SSE are recognized. Except for the NNW-SSE set, all the other sets host calcite veins and barren joints, evidencing a multistage development by several deformation episodes, including shear reactivation. Orthogonal patterns defined by the NNE-SSW/WNW-ESE and NNW-SSE/WSW-ENE systems are characteristic of some tectonostratigraphic units of the MCE, but the sets of each one of the systems are genetically independent. They result from specific deformation episodes undergone by the studied area in the course of its Meso-Cenozoic evolution. NNE-SSW calcite veins were the first to form during Middle Jurassic fault-controlled subsidence. A renewal of this set as barren joints took place during the Eocene Pyrenean compressive phase. The WSW-ENE and WNW-ESE sets have a restricted spatial distribution and relate to transient compressive episodes of the Middle - Late Jurassic and Jurassic - Cretaceous transitions, respectively. The NW-SE set, also characteristic of a specific region, formed during the Late Jurassic rifting and is related to local NE-SW tension dependent on block tilting towards a major NW-SE fault. The Miocene Betic compressive phase is responsible for the formation of the NNW-SSE set, which is widespread throughout the MCE.

Inactivation of MSH3 by promoter methylation correlates with primary tumor stage in nasopharyngeal carcinoma

PubMed Central

Ni, Haifeng; Jiang, Bo; Zhou, Zhen; Yuan, Xiaoyang; Cao, Xiaolin; Huang, Guangwu; Li, Yong

2017-01-01

The aim of this study was to investigate the inactivation of the MutS homolog human 3 (MSH3) gene by promoter methylation in nasopharyngeal carcinoma (NPC). Methylation-specific PCR, semi-quantitative reverse transcription PCR and immunohistochemical analysis were used to detect methylation and the mRNA and protein expression levels of MSH3 in 54 cases of NPC tissues and 16 cases of normal nasopharyngeal epithelial (NNE) tissues. The association between promoter methylation and mRNA expression, and the mRNA and protein expression of the gene and clinical factors was analyzed. The promoter methylation of MSH3 was detected in 50% (27/54) of the primary tumors, but not in the 16 NNE tissues. The mRNA and protein expression levels were significantly decreased in the 54 cases of human NPC as compared to the 16 NNE tissues (P<0.05). The MSH3-methylated cases exhibited significantly lower mRNA and protein expression levels than the unmethylated cases (P<0.05). The MSH3 mRNA and protein expression levels were significantly associated with the variable T stage (P<0.05); however, they did not correlate with the age and sex of the patients, or with the N stage, TNM classification or histopathological subtype (P>0.05). On the whole, MSH3 was frequently inactivated by promoter methylation and its mRNA and protein expression correlated with the primary tumor stage in NPC. PMID:28656302

Widespread occurrence and seasonal variation of pharmaceuticals in surface waters and municipal wastewater treatment plants in central Finland.

PubMed

Lindholm-Lehto, Petra C; Ahkola, Heidi S J; Knuutinen, Juha S; Herve, Sirpa H

2016-04-01

The presence of five selected pharmaceuticals, consisting of four anti-inflammatory drugs, diclofenac, ibuprofen, ketoprofen, naproxen, and an antiepileptic drug carbamazepine, was determined at four municipal wastewater treatment plants (WWTPs) and in the receiving waterway in central Finland. The samples were taken from influents and effluents of the WWTPs and from surface water of six locations along the water way, including northern Lake Päijänne. In addition, seasonal variation in the area was determined by comparing the concentrations in the winter and summer. The samples were analyzed by liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) in the multiple reaction monitoring mode. The concentrations in the influents and effluents ranged from hundreds of nanogram per liter to microgram per liter while ranged from tens of nanogram per liter in northern parts of the waterway to hundreds of nanogram per liter in northern Lake Päijänne near the city area. In addition, the concentrations were higher in the winter compared to summer time in surface water due to decreased temperature and solar irradiation. On the other hand, higher concentrations of ibuprofen, ketoprofen, and naproxen were found in summer at the WWTPs, possibly due to seasonal variations in consumption. In conclusion, there are considerable amounts of pharmaceuticals not only in influents and effluents of the WWTPs but also in lake water along the waterway and in northern Lake Päijänne.

Attitudes of UK doctors towards euthanasia and physician-assisted suicide: a systematic literature review.

PubMed

McCormack, Ruaidhri; Clifford, Margaret; Conroy, Marian

2012-01-01

To review studies over a 20-year period that assess the attitudes of UK doctors concerning active, voluntary euthanasia (AVE) and physician-assisted suicide (PAS), assess efforts to minimise bias in included studies, determine the effect of subgroup variables (e.g. age, gender) on doctors' attitudes, and make recommendations for future research. Three electronic databases, four pertinent journals, reference lists of included studies. Literature search of English articles between January 1990 and April 2010. Studies were excluded if they did not present independent data (e.g. commentaries) or if they related to doctors outside the UK, patients younger than 18 years old, terminal sedation, withdrawing or withholding treatment, or double-effect. Quantitative and qualitative data were extracted. Following study selection and data extraction, 15 studies were included. UK doctors oppose the introduction of both AVE and PAS in the majority of studies. Degree of religiosity appeared as a statistically significant factor in influencing doctors' attitudes. The top three themes in the qualitative analysis were the provision of palliative care, adequate safeguards in the event of AVE or PAS being introduced, and a profession to facilitate AVE or PAS that does not include doctors. UK doctors appear to oppose the introduction of AVE and PAS, even when one considers the methodological limitations of included studies. Attempts to minimise bias in included studies varied. Further studies are necessary to establish if subgroup variables other than degree of religiosity influence attitudes, and to thoroughly explore the qualitative themes that appeared.

GRC-2010-C-05148

NASA Image and Video Library

2006-11-08

Communications, Navigation, and Network Reconfigurable Test-bed (CoNNeCT) Flight Hardware Compatibility Test Sets - Glenn Research Center and Networks Integration Management Office (NIMO) Testing for the Tracking and Data Relay Satellite System (TDRSS) - Goddard Space Flight Center Testing

GRC-2010-C-05136

NASA Image and Video Library

2006-11-16

Communications, Navigation, and Network Reconfigurable Test-bed (CoNNeCT) Flight Hardware Compatibility Test Sets - Glenn Research Center and Networks Integration Management Office (NIMO) Testing for the Tracking and Data Relay Satellite System (TDRSS) - Goddard Space Flight Center Testing

7 CFR 980.212 - Import regulations; tomatoes.

Code of Federal Regulations, 2014 CFR

2014-01-01

...-2902 1 All California points Officer-in-charge, 784 South Central Ave., room 266, Los Angeles, Calif..., Santurce, P.R. 00908, phone 809-783-2230 or 4116 2 New York, N.Y Officer-in-charge, room 28A, Hunts Point... Officer-in-charge, 1350 Northwest 12th Ave., room 530, Miami, Fla. 33136, phone 305-324-6116 or 6117 1 All...

7 CFR 980.212 - Import regulations; tomatoes.

Code of Federal Regulations, 2013 CFR

2013-01-01

...-2902 1 All California points Officer-in-charge, 784 South Central Ave., room 266, Los Angeles, Calif..., Santurce, P.R. 00908, phone 809-783-2230 or 4116 2 New York, N.Y Officer-in-charge, room 28A, Hunts Point... Officer-in-charge, 1350 Northwest 12th Ave., room 530, Miami, Fla. 33136, phone 305-324-6116 or 6117 1 All...

7 CFR 980.212 - Import regulations; tomatoes.

Code of Federal Regulations, 2012 CFR

2012-01-01

...-2902 1 All California points Officer-in-charge, 784 South Central Ave., room 266, Los Angeles, Calif..., Santurce, P.R. 00908, phone 809-783-2230 or 4116 2 New York, N.Y Officer-in-charge, room 28A, Hunts Point... Officer-in-charge, 1350 Northwest 12th Ave., room 530, Miami, Fla. 33136, phone 305-324-6116 or 6117 1 All...

Correlating Near-Source Rock Damage from Single-Hole Explosions to Seismic Waves (Postprint)

DTIC Science & Technology

2012-05-07

Technical Paper APPROVED FOR PUBLIC RELEASE; DISTRIBUTION IS UNLIMITED. AIR FORCE RESEARCH LABORATORY Space Vehicles Directorate...Space Vehicles Directorate 3550 Aberdeen Ave SE 3550 Aberdeen Ave SE 11. SPONSOR/MONITOR’S REPORT Kirtland AFB, NM 87117-5776...function of pressure, • Fluid permeability as a function of pressure, • Electrical resistivity as a function of pressure, and • Rock strength. The

2. HORSESHOE CURVE IN GLACIER POINT ROAD NEAR GLACIER POINT. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. HORSESHOE CURVE IN GLACIER POINT ROAD NEAR GLACIER POINT. HALF DOME AT CENTER REAR. LOOKING NNE. GIS N-37 43 44.3 / W-119 34 14.1 - Glacier Point Road, Between Chinquapin Flat & Glacier Point, Yosemite Village, Mariposa County, CA

4. VISTA POINT AND INTERPRETIVE PLAQUE AT LEE VINING CANYON. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

4. VISTA POINT AND INTERPRETIVE PLAQUE AT LEE VINING CANYON. NOTE ROAD CUT ON CANYON WALL. LOOKING NNE. GIS: N-37 56 30.3 / 119 13 44.8 - Tioga Road, Between Crane Flat & Tioga Pass, Yosemite Village, Mariposa County, CA

Complete mitochondrial genome sequences of the northern spotted owl (Strix occidentalis caurina) and the barred owl (Strix varia; Aves: Strigiformes: Strigidae) confirm the presence of a duplicated control region

PubMed Central

Henderson, James B.; Sellas, Anna B.; Fuchs, Jérôme; Bowie, Rauri C.K.; Dumbacher, John P.

2017-01-01

We report here the successful assembly of the complete mitochondrial genomes of the northern spotted owl (Strix occidentalis caurina) and the barred owl (S. varia). We utilized sequence data from two sequencing methodologies, Illumina paired-end sequence data with insert lengths ranging from approximately 250 nucleotides (nt) to 9,600 nt and read lengths from 100–375 nt and Sanger-derived sequences. We employed multiple assemblers and alignment methods to generate the final assemblies. The circular genomes of S. o. caurina and S. varia are comprised of 19,948 nt and 18,975 nt, respectively. Both code for two rRNAs, twenty-two tRNAs, and thirteen polypeptides. They both have duplicated control region sequences with complex repeat structures. We were not able to assemble the control regions solely using Illumina paired-end sequence data. By fully spanning the control regions, Sanger-derived sequences enabled accurate and complete assembly of these mitochondrial genomes. These are the first complete mitochondrial genome sequences of owls (Aves: Strigiformes) possessing duplicated control regions. We searched the nuclear genome of S. o. caurina for copies of mitochondrial genes and found at least nine separate stretches of nuclear copies of gene sequences originating in the mitochondrial genome (Numts). The Numts ranged from 226–19,522 nt in length and included copies of all mitochondrial genes except tRNAPro, ND6, and tRNAGlu. Strix occidentalis caurina and S. varia exhibited an average of 10.74% (8.68% uncorrected p-distance) divergence across the non-tRNA mitochondrial genes. PMID:29038757

Cellular protein quality control and the evolution of aggregates in spinocerebellar ataxia type 3 (SCA3).

PubMed

Seidel, K; Meister, M; Dugbartey, G J; Zijlstra, M P; Vinet, J; Brunt, E R P; van Leeuwen, F W; Rüb, U; Kampinga, H H; den Dunnen, W F A

2012-10-01

A characteristic of polyglutamine diseases is the increased propensity of disease proteins to aggregate, which is thought to be a major contributing factor to the underlying neurodegeneration. Healthy cells contain mechanisms for handling protein damage, the protein quality control, which must be impaired or inefficient to permit proteotoxicity under pathological conditions. We used a quantitative analysis of immunohistochemistry of the pons of eight patients with the polyglutamine disorder spinocerebellar ataxia type 3. We employed the anti-polyglutamine antibody 1C2, antibodies against p62 that is involved in delivering ubiquitinated protein aggregates to autophagosomes, antibodies against the chaperones HSPA1A and DNAJB1 and the proteasomal stress marker UBB⁺¹. The 1C2 antibody stained neuronal nuclear inclusions (NNIs), diffuse nuclear staining (DNS), granular cytoplasmic staining (GCS) and combinations, with reproducible distribution. P62 always co-localized with 1C2 in NNI. DNS and GCS co-stained with a lower frequency. UBB⁺¹ was present in a subset of neurones with NNI. A subset of UBB⁺¹-containing neurones displayed increased levels of HSPA1A, while DNAJB1 was sequestered into the NNI. Based on our results, we propose a model for the aggregation-associated pathology of spinocerebellar ataxia type 3: GCS and DNS aggregation likely represents early stages of pathology, which progresses towards formation of p62-positive NNI. A fraction of NNI exhibits UBB⁺¹ staining, implying proteasomal overload at a later stage. Subsequently, the stress-inducible HSPA1A is elevated while DNAJB1 is recruited into NNIs. This indicates that the stress response is only induced late when all endogenous protein quality control systems have failed. © 2011 The Authors. Neuropathology and Applied Neurobiology © 2011 British Neuropathological Society.

Failure of Colorectal Surgical Site Infection Predictive Models Applied to an Independent Dataset: Do They Add Value or Just Confusion?

PubMed

Bergquist, John R; Thiels, Cornelius A; Etzioni, David A; Habermann, Elizabeth B; Cima, Robert R

2016-04-01

Colorectal surgical site infections (C-SSIs) are a major source of postoperative morbidity. Institutional C-SSI rates are modeled and scrutinized, and there is increasing movement in the direction of public reporting. External validation of C-SSI risk prediction models is lacking. Factors governing C-SSI occurrence are complicated and multifactorial. We hypothesized that existing C-SSI prediction models have limited ability to accurately predict C-SSI in independent data. Colorectal resections identified from our institutional ACS-NSQIP dataset (2006 to 2014) were reviewed. The primary outcome was any C-SSI according to the ACS-NSQIP definition. Emergency cases were excluded. Published C-SSI risk scores: the National Nosocomial Infection Surveillance (NNIS), Contamination, Obesity, Laparotomy, and American Society of Anesthesiologists (ASA) class (COLA), Preventie Ziekenhuisinfecties door Surveillance (PREZIES), and NSQIP-based models were compared with receiver operating characteristic (ROC) analysis to evaluate discriminatory quality. There were 2,376 cases included, with an overall C-SSI rate of 9% (213 cases). None of the models produced reliable and high quality C-SSI predictions. For any C-SSI, the NNIS c-index was 0.57 vs 0.61 for COLA, 0.58 for PREZIES, and 0.62 for NSQIP: all well below the minimum "reasonably" predictive c-index of 0.7. Predictions for superficial, deep, and organ space SSI were similarly poor. Published C-SSI risk prediction models do not accurately predict C-SSI in our independent institutional dataset. Application of externally developed prediction models to any individual practice must be validated or modified to account for institution and case-mix specific factors. This questions the validity of using externally or nationally developed models for "expected" outcomes and interhospital comparisons. Copyright © 2016 American College of Surgeons. Published by Elsevier Inc. All rights reserved.

Preliminary results of an anteverting triple periacetabular osteotomy for the treatment of hip instability in Down syndrome.

PubMed

Maranho, D A; Kim, Y-J; Williams, K A; Novais, E N

2018-02-01

To investigate the outcomes of an anteverting triple periacetabular osteotomy for the treatment of hip instability in skeletally immature patients with Down syndrome. We evaluated 16 patients (21 hips) with Down syndrome and hip instability who underwent an anteverting triple periacetabular osteotomy between 2007 and 2016. There were nine females and seven males with an average age of 7.4 years SD 2.0. We assessed the level of hip pain, gait ability and clinical stability at a minimum of one year after surgery. Radiographic evaluation included pre- and postoperative lateral centre-edge angle (LCEA), Tönnis acetabular angle and extrusion index. After an average follow-up of 4.1 years SD 2.6, 20 of 21 hips (95%) remained clinically stable. In all, 12 of 16 (75%) patients had a full gait without a major limp, but three patients (19%) had a persistent limp. Of the 21 procedures, one hip (5%) was considered a failure due to persistent instability. There was a mean increase of 18.3º SD 15.3º of the LCEA (p < 0.001); a mean decrease of 15.2º SD 11.6º (p < 0.001) for the Tönnis angle and the extrusion index had a mean decrease of 0.27 SD 0.20 (p < 0.001). The most common complications were minor and included nonunion of the pubis or ischium (24%) and stress fractures of the pubis and ischium (14%). Only one patient required unplanned surgery for the treatment of an infection; which was considered a major complication. The anteverting triple periacetabular osteotomy provided global deformity correction and achieved hip stability in 95% of the hips after a mean follow-up of 4.1 years. Therapeutic level IV.

Anterior delayed gadolinium-enhanced MRI of cartilage values predict joint failure after periacetabular osteotomy.

PubMed

Kim, Sang Do; Jessel, Rebecca; Zurakowski, David; Millis, Michael B; Kim, Young-Jo

2012-12-01

Several available compositional MRIs seem to detect early osteoarthritis before radiographic appearance. Delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) has been most frequently used in clinical studies and reportedly predicts premature joint failure in patients undergoing Bernese periacetabular osteotomies (PAOs). We asked, given regional variations in biochemical composition in dysplastic hips, whether the dGEMRIC index of the anterior joint would better predict premature joint failure after PAOs than the coronal dGEMRIC index as previously reported. We retrospectively reviewed 43 hips in 41 patients who underwent Bernese PAO for hip dysplasia. Thirty-seven hips had preserved joints after PAOs and six were deemed premature failures based on pain, joint space narrowing, or subsequent THA. We used dGEMRIC to determine regional variations in biochemical composition. Preoperative demographic and clinical outcome score, radiographic measures of osteoarthritis and severity of dysplasia, and dGEMRIC indexes from different hip regions were analyzed in a multivariable regression analysis to determine the best predictor of premature joint failure. Minimum followup was 24 months (mean, 32 months; range, 24-46 months). The two cohorts were similar in age and sex distribution. Severity of dysplasia was similar as measured by lateral center-edge, anterior center-edge, and Tönnis angles. Preoperative pain, joint space width, Tönnis grade, and coronal and sagittal dGEMRIC indexes differed between groups. The dGEMRIC index in the anterior weightbearing region of the hip was lower in the prematurely failed group and was the best predictor. Success of PAO depends on the amount of preoperative osteoarthritis. These degenerative changes are seen most commonly in the anterior joint. The dGEMRIC index of the anterior joint may better predict premature joint failure than radiographic measures of hip osteoarthritis and coronal dGEMRIC index. Level II, prognostic study. See

Artificial neural networks for stiffness estimation in magnetic resonance elastography.

PubMed

Murphy, Matthew C; Manduca, Armando; Trzasko, Joshua D; Glaser, Kevin J; Huston, John; Ehman, Richard L

2018-07-01

To investigate the feasibility of using artificial neural networks to estimate stiffness from MR elastography (MRE) data. Artificial neural networks were fit using model-based training patterns to estimate stiffness from images of displacement using a patch size of ∼1 cm in each dimension. These neural network inversions (NNIs) were then evaluated in a set of simulation experiments designed to investigate the effects of wave interference and noise on NNI accuracy. NNI was also tested in vivo, comparing NNI results against currently used methods. In 4 simulation experiments, NNI performed as well or better than direct inversion (DI) for predicting the known stiffness of the data. Summary NNI results were also shown to be significantly correlated with DI results in the liver (R 2  = 0.974) and in the brain (R 2  = 0.915), and also correlated with established biological effects including fibrosis stage in the liver and age in the brain. Finally, repeatability error was lower in the brain using NNI compared to DI, and voxel-wise modeling using NNI stiffness maps detected larger effects than using DI maps with similar levels of smoothing. Artificial neural networks represent a new approach to inversion of MRE data. Summary results from NNI and DI are highly correlated and both are capable of detecting biologically relevant signals. Preliminary evidence suggests that NNI stiffness estimates may be more resistant to noise than an algebraic DI approach. Taken together, these results merit future investigation into NNIs to improve the estimation of stiffness in small regions. Magn Reson Med 80:351-360, 2018. © 2017 International Society for Magnetic Resonance in Medicine. © 2017 International Society for Magnetic Resonance in Medicine.

Impact of revising the National Nosocomial Infection Surveillance System definition for catheter-related bloodstream infection in ICU: reproducibility of the National Healthcare Safety Network case definition in an Australian cohort of infection control professionals.

PubMed

Worth, Leon J; Brett, Judy; Bull, Ann L; McBryde, Emma S; Russo, Philip L; Richards, Michael J

2009-10-01

Effective and comparable surveillance for central venous catheter-related bloodstream infections (CLABSIs) in the intensive care unit requires a reproducible case definition that can be readily applied by infection control professionals. Using a questionnaire containing clinical cases, reproducibility of the National Nosocomial Infection Surveillance System (NNIS) surveillance definition for CLABSI was assessed in an Australian cohort of infection control professionals participating in the Victorian Hospital Acquired Infection Surveillance System (VICNISS). The same questionnaire was then used to evaluate the reproducibility of the National Healthcare Safety Network (NHSN) surveillance definition for CLABSI. Target hospitals were defined as large metropolitan (1A) or other large hospitals (non-1A), according to the Victorian Department of Human Services. Questionnaire responses of Centers for Disease Control and Prevention NHSN surveillance experts were used as gold standard comparator. Eighteen of 21 eligible VICNISS centers participated in the survey. Overall concordance with the gold standard was 57.1%, and agreement was highest for 1A hospitals (60.6%). The proportion of congruently classified cases varied according to NNIS criteria: criterion 1 (recognized pathogen), 52.8%; criterion 2a (skin contaminant in 2 or more blood cultures), 83.3%; criterion 2b (skin contaminant in 1 blood culture and appropriate antimicrobial therapy instituted), 58.3%; non-CLABSI cases, 51.4%. When survey questions regarding identification of cases of CLABSI criterion 2b were removed (consistent with the current NHSN definition), overall percentage concordance increased to 62.5% (72.2% for 1A centers). Further educational interventions are required to improve the discrimination of primary and secondary causes of bloodstream infection in Victorian intensive care units. Although reproducibility of the CLABSI case definition is relatively poor, adoption of the revised NHSN definition

Conflict over Relocation Divides a Catholic Law School

ERIC Educational Resources Information Center

Mangan, Katherine

2007-01-01

A mutiny may be brewing at a Catholic law school whose board has voted to pack it up and move it from Ann Arbor, Michigan to a rural community in southwest Florida. More than half of the professors at Ave Maria School of Law are fighting the move to Ave Maria, Florida, the town being created by Thomas S. Monaghan, the Domino's Pizza mogul who…

Non-Traditional Organizational Design Concepts

DTIC Science & Technology

1982-05-01

specialists benefit, for recognition ave. to ave. have associatelon with project; resembles job enrichment. 9 12 . Structure/concept Yes Synonym for program...provisions Little Wall (1980): Form of recognition is per- for recognition ceived by functional specialists ; resem- bles job enrichment. 12 ...Indirect reward to functional recognition specialists ; resembles job enrichment. 12 . Structure/concept No • S applied in the pub- lic sector 108 U

Surveying the Dynamic Radio Sky with the Long Wavelength Demonstrator Array

DTIC Science & Technology

2010-10-01

and potentially the Lunar Radio Array. Subject headings: instrumentation: interferometers — methods : observational — radio continuum: gen- eral 1Remote...Sensing Division, Naval Research Laboratory, 4555 Overlook Ave. SW, Washington, DC 20375 USA 2NASA Lunar Science Institute, NASA Ames Research Center...Moffett Field, CA 94035 USA 3Space Science Division, Naval Research Laboratory, 4555 Overlook Ave. SW, Washington, DC 20375-5382 USA 4Praxis, Inc

The Effects of Category Generalizations and Instance Similarity on Schema Abstraction.

DTIC Science & Technology

1980-10-07

reading; musical ’a-ite: classical, jazz, rock, disco, folk, country; sport: volleyball, basketball. bowling, squash, racquetball, handball . The space...Psychology 1845 Elena Ave., Fourth Floor 33 Kirkland Street Redondo Beach , CA 90277 Cambridge, MA 02138 1 Dr. Donald A Norman Mr. Marlin Kroger Dept. of...So. California Department of Computer Science Behavioral Technology Labs Rutgers University 1845 S. Elena Ave. ew Brunswick, NJ 08903 Redondo Beach

Improved VAS regression soundings of mesoscale temperature features observed during the atmospheric variability experiment on 6 March 1982. [VISSR Atmospheric Sounder

NASA Technical Reports Server (NTRS)

Chesters, Dennis; Keyser, Dennis A.; Larko, David E.; Uccellini, Louis W.

1988-01-01

In 1982, the VISSR Atmospheric Sounder (VAS) on the GOES satellite performed the Atmospheric Variability Experiment (AVE) to verify VAS's mesoscale-sounding capabilities. Attention is given to the AVE network in the late afternoon of March 6, 1982, after a winter storm had passed over Texas, in order to ascertain whether such temperature profile deviations from the average lapse rate as a midlevel cold pool (which should decrease the brightness of several IR channels) can be retrieved from VAS radiances. Two simple enhancements are introduced: the regression matrix is calculated using the AVE asynoptic radiosondes launched from NWS sites in the region, and a change of the statistical conditioning factor from the conservative 10/1 SNR to a more optimistic 100/1 for those VAS channels that are more sensitive to tropospheric temperature.

Inactivation of MSH3 by promoter methylation correlates with primary tumor stage in nasopharyngeal carcinoma.

PubMed

Ni, Haifeng; Jiang, Bo; Zhou, Zhen; Yuan, Xiaoyang; Cao, Xiaolin; Huang, Guangwu; Li, Yong

2017-09-01

The aim of this study was to investigate the inactivation of the MutS homolog human 3 (MSH3) gene by promoter methylation in nasopharyngeal carcinoma (NPC). Methylation‑specific PCR, semi‑quantitative reverse transcription PCR and immunohistochemical analysis were used to detect methylation and the mRNA and protein expression levels of MSH3 in 54 cases of NPC tissues and 16 cases of normal nasopharyngeal epithelial (NNE) tissues. The association between promoter methylation and mRNA expression, and the mRNA and protein expression of the gene and clinical factors was analyzed. The promoter methylation of MSH3 was detected in 50% (27/54) of the primary tumors, but not in the 16 NNE tissues. The mRNA and protein expression levels were significantly decreased in the 54 cases of human NPC as compared to the 16 NNE tissues (P<0.05). The MSH3‑methylated cases exhibited significantly lower mRNA and protein expression levels than the unmethylated cases (P<0.05). The MSH3 mRNA and protein expression levels were significantly associated with the variable T stage (P<0.05); however, they did not correlate with the age and sex of the patients, or with the N stage, TNM classification or histopathological subtype (P>0.05). On the whole, MSH3 was frequently inactivated by promoter methylation and its mRNA and protein expression correlated with the primary tumor stage in NPC.

Software Defined GPS Receiver for International Space Station

NASA Technical Reports Server (NTRS)

Duncan, Courtney B.; Robison, David E.; Koelewyn, Cynthia Lee

2011-01-01

JPL is providing a software defined radio (SDR) that will fly on the International Space Station (ISS) as part of the CoNNeCT project under NASA's SCaN program. The SDR consists of several modules including a Baseband Processor Module (BPM) and a GPS Module (GPSM). The BPM executes applications (waveforms) consisting of software components for the embedded SPARC processor and logic for two Virtex II Field Programmable Gate Arrays (FPGAs) that operate on data received from the GPSM. GPS waveforms on the SDR are enabled by an L-Band antenna, low noise amplifier (LNA), and the GPSM that performs quadrature downconversion at L1, L2, and L5. The GPS waveform for the JPL SDR will acquire and track L1 C/A, L2C, and L5 GPS signals from a CoNNeCT platform on ISS, providing the best GPS-based positioning of ISS achieved to date, the first use of multiple frequency GPS on ISS, and potentially the first L5 signal tracking from space. The system will also enable various radiometric investigations on ISS such as local multipath or ISS dynamic behavior characterization. In following the software-defined model, this work will create a highly portable GPS software and firmware package that can be adapted to another platform with the necessary processor and FPGA capability. This paper also describes ISS applications for the JPL CoNNeCT SDR GPS waveform, possibilities for future global navigation satellite system (GNSS) tracking development, and the applicability of the waveform components to other space navigation applications.

Test Waveform Applications for JPL STRS Operating Environment

NASA Technical Reports Server (NTRS)

Lux, James P.; Peters, Kenneth J.; Taylor, Gregory H.; Lang, Minh; Stern, Ryan A.; Duncan, Courtney B.

2013-01-01

This software demonstrates use of the JPL Space Telecommunications Radio System (STRS) Operating Environment (OE), tests APIs (application programming interfaces) presented by JPL STRS OE, and allows for basic testing of the underlying hardware platform. This software uses the JPL STRS Operating Environment ["JPL Space Tele com - munications Rad io System Operating Environment,"(NPO-4776) NASA Tech Briefs, commercial edition, Vol. 37, No. 1 (January 2013), p. 47] to interact with the JPL-SDR Software Defined Radio developed for the CoNNeCT (COmmunications, Navigation, and Networking rEconfigurable Testbed) Project as part of the SCaN Testbed installed on the International Space Station (ISS). These are the first applications that are compliant with the new NASA STRS Architecture Standard. Several example waveform applications are provided to demonstrate use of the JPL STRS OE for the JPL-SDR platform used for the CoNNeCT Project. The waveforms provide a simple digitizer and playback capability for the SBand RF slice, and a simple digitizer for the GPS slice [CoNNeCT Global Positioning System RF Module, (NPO-47764) NASA Tech Briefs, commercial edition, Vol. 36, No. 3 (March 2012), p. 36]. These waveforms may be used for hardware test, as well as for on-orbit or laboratory checkout. Additional example waveforms implement SpaceWire and timer modules, which can be used for time transfer and demonstration of communication between the two Xilinx FPGAs in the JPLSDR. The waveforms are also compatible with ground-based use of the JPL STRS OE on radio breadboards and Linux.

Modeling Groundwater Flow System of a Drainage Basin in the Basement Complex Environment of Southwestern Nigera

NASA Astrophysics Data System (ADS)

Akinwumiju, Akinola S.; Olorunfemi, Martins O.

2018-05-01

This study attempted to model the groundwater flow system of a drainage basin within the Basement Complex environment of Southwestern Nigeria. Four groundwater models were derived from Vertical Electrical Sounding (VES) Data, remotely sensed data, geological information (hydrolineaments and lithology) and borehole data. Subsequently, two sub-surface (local and regional) flow systems were delineated in the study area. While the local flow system is controlled by surface topography, the regional flow system is controlled by the networks of intermediate and deep seated faults/fractures. The local flow system is characterized by convergence, divergence, inflow and outflow in places, while the regional flow system is dominated by NNE-SSW and W-E flow directions. Minor flow directions include NNW-SSE and E-W with possible linkages to the main flow-paths. The NNE-SSW regional flow system is a double open ended flow system with possible linkage to the Niger Trough. The W-E regional flow system is a single open ended system that originates within the study area (with possible linkage to the NNE-SSW regional flow system) and extends to Ikogosi in the adjoining drainage basin. Thus, the groundwater drainage basin of the study area is much larger and extensive than its surface drainage basin. The all year round flowing (perennial) rivers are linked to groundwater outcrops from faults/fractures and contact zones. Consequently, larger percentage of annual rainwater usually leaves the basin in form of runoff and base flow. Therefore, the basin is categorized as a donor basin but with suspected subsurface water input at its northeastern axis.

Directory of Federal Contractors and Cognizant Audit Offices

DTIC Science & Technology

1994-12-31

34 qLELECTE 11. Title: , Directory of Federal Contractors and Cognizant Audit Offices 12. Performing Organization: 13 . Performing Report #: 14...GRAND AVE EL SEGUNDO CA 90245 3106150311 COMPUTER SCIENCE CORPORATION 04311 044 BUILDING T-164 FT. HUNTER LIGGE CA 93928 4083882775 COMPUTER SCIENCE...INC 03621 110 2650 INDUSTRIAL PKW MARINETTE WI 54143 7157359058 FIRE SYS INC 01271 084 5110 S. MACDILL AVE TAMPA FL 33611 6138379491 FIRE-BANN

Inventory of File WAFS_blended_2014102006f06.grib2

Science.gov Websites

) [%] 004 700 mb CTP 6 hour fcst In-Cloud Turbulence [%] spatial ave,code table 4.15=3,#points=1 005 700 mb CTP 6 hour fcst In-Cloud Turbulence [%] spatial max,code table 4.15=3,#points=1 006 600 mb CTP 6 hour fcst In-Cloud Turbulence [%] spatial ave,code table 4.15=3,#points=1 007 600 mb CTP 6 hour fcst In

High-Speed Laser Imaging, Emission and Temperature Measurements of Explosions

DTIC Science & Technology

2006-09-01

of these optical fibers illuminated the entrance slit of a dedicated Ocean Optics model HR-2000 spectrograph. The seven spectrographs were modified...Hewlett-Packard). The spectral response of the system was calibrated using an ARC Model XS432 Xenon lamp. Time resolution is approximately 12...F FOROHAR 101 STRAUSS AVE INDIAN HEAD MD 20640-5035 1 NAVAL SURFACE WARFARE CTR CODE 920J R GUIRGUIS 101 STRAUSS AVE INDIAN

Question Generation via Overgenerating Transformations and Ranking

DTIC Science & Technology

2009-01-01

School of Computer Science Carnegie Mellon University 5000 Forbes Ave., Pittsburgh, PA 15213 www.lti.cs.cmu.edu c©2009, Michael Heilman and Noah A...PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Carnegie Mellon University ,School of Computer Science,5000 Forbes Ave,Pittsburgh,PA,15213 8...1967), in particular those that view a question as a transformation of a canonical declarative sentence ( Chomsky , 1973). In computational linguistics

Testing the role of interspecific competition in the evolutionary origin of elevational zonation: an example with Buarremon brush-finches (Aves, Emberizidae) in the neotropical mountains.

PubMed

Cadena, Carlos Daniel

2007-05-01

Interspecific competition might drive the evolution of ecological niches and result in pairs of formerly competing species segregating along ecological gradients following a process of character displacement. This mechanism has been proposed to account for replacement of related species along gradients of elevation in many areas of the world, but the fundamental issue of whether competition is responsible for the origin of elevational replacements has not been tested. To test hypotheses about the role of interspecific competition in the origin of complementary elevational ranges, I combined molecular phylogenetics, phylogeography, and population genetic analyses on Buarremon torquatus and B. brunneinucha (Aves, Emberizidae), whose patterns of elevational distribution suggest character displacement or ecological release. The hypothesis that elevational distributions in these species changed in opposite directions as a result of competition is untenable because: (1) a historical expansion of the range of B. brunneinucha into areas occupied by B. torquatus was not accompanied by a shift in the elevational range of the former species; (2) when B. brunneinucha colonized the range of B. torquatus, lineages of the latter distributions had already diverged; and (3) historical trends in effective population size do not suggest populations with elevational ranges abutting those of putative competitors have declined as would be expected if competition caused range contractions. However, owing to uncertainty in coalescent estimates of historical population sizes, the hypothesis that some populations of B. torquatus have declined cannot be confidently rejected, which suggests asymmetric character displacement might have occurred. I suggest that the main role of competition in elevational zonation may be to act as a sorting mechanism that allows the coexistence along mountain slopes only of ecologically similar species that differ in elevational distributions prior to attaining

Effects of changing climate on reference crop evapotranspiration over 1961-2013 in Xinjiang, China

NASA Astrophysics Data System (ADS)

Yao, Ning; Li, Yi; Sun, Changfeng

2018-01-01

To know the importance of different climate variables on reference crop evapotranspiration ( ET o), a step-by-step sensitivity analysis of ET o to single, two, and multi-climate variables ( C) was conducted. ET o in north, south, and entire Xinjiang Province, China, over 1961-2013 was estimated using the Penman-Monteith equation. Trends in the involved six Cs (i.e., minimum temperature— T min, average temperature— T ave, maximum temperature— T max, wind speed at 2 m— U 2, sunshine hour— n, and relative humidity— RH) were detected by the modified Mann-Kendall test. Nineteen scenarios of changed Cs were preset to obtain recalculated ET o values considering the actual trend in each C and the Pearson's correlation relationship between ET o and Cs. The results showed that ET o was mostly sensitive to T max, U 2, and n. Sensitivity of ET o to the two overlapped changes of T min and T max caused larger increases in ET o than T max and T ave, T ave and T max, T max and (- n), T max and RH, T max and (- U 2), and T min and T ave, but the overlapped changes (- U 2) and (- n) caused larger decreases in ET o than the other two C scenarios. The simultaneously increased T max, T min, T ave, and RH plus decreased U 2 and n had caused the actual decreases in ET o in Xinjiang. In general, the effects of decreased U 2 and n on decreasing ET o compensated the effects of increased T max on decreasing ET o in Xinjiang.

s09-48-3139

NASA Image and Video Library

2009-06-25

STS009-48-3139 (28 Nov-8 Dec 1983) --- Canada (Quebec) the contrast between forest, water, and snow make the Manicouagane impact formation stand out. Location: 150 miles (250 Km) NNW of Sept Iles or 500 miles (800 Km) NNE of Montreal on the Canadian Shield.

6. OLD AND NEW TIOGA ROAD. NOTE REMNANTS OF OLD ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

6. OLD AND NEW TIOGA ROAD. NOTE REMNANTS OF OLD ROAD ON LEFT. NOTE ROAD CUT ON CANYON WALL IN CENTER REAR. LOOKING NNE. GIS: N-37 56 19.5 / W-119 13 53.3 - Tioga Road, Between Crane Flat & Tioga Pass, Yosemite Village, Mariposa County, CA

HORSESHOE CURVE IN GLACIER POINT ROAD NEAR GLACIER POINT. HALF ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

HORSESHOE CURVE IN GLACIER POINT ROAD NEAR GLACIER POINT. HALF DOME AT CENTER REAR. SAME VIEW AT CA-157-2. LOOKING NNE. GIS: N-37' 43 44.3 / W-119 34 14.1 - Glacier Point Road, Between Chinquapin Flat & Glacier Point, Yosemite Village, Mariposa County, CA

GIS based 3D visualization of subsurface and surface lineaments / faults and their geological significance, northern tamil nadu, India

NASA Astrophysics Data System (ADS)

Saravanavel, J.; Ramasamy, S. M.

2014-11-01

The study area falls in the southern part of the Indian Peninsular comprising hard crystalline rocks of Archaeozoic and Proterozoic Era. In the present study, the GIS based 3D visualizations of gravity, magnetic, resistivity and topographic datasets were made and therefrom the basement lineaments, shallow subsurface lineaments and surface lineaments/faults were interpreted. These lineaments were classified as category-1 i.e. exclusively surface lineaments, category-2 i.e. surface lineaments having connectivity with shallow subsurface lineaments and category-3 i.e. surface lineaments having connectivity with shallow subsurface lineaments and basement lineaments. These three classified lineaments were analyzed in conjunction with known mineral occurrences and historical seismicity of the study area in GIS environment. The study revealed that the category-3 NNE-SSW to NE-SW lineaments have greater control over the mineral occurrences and the N-S, NNE-SSW and NE-SW, faults/lineaments control the seismicities in the study area.

Station Climatic Summaries, North America. Volume 2. Alaska, Canada and Greenland

DTIC Science & Technology

1993-02-01

36 IZ50 NNE 13 5$ 9 J7 1 4 17 11 a a 13 4 ISO NNE 4 52 9 1 21 1 41 19. :5 :S 10 1, 𔃻:: Z. 1:9 1 4ý1 11 1 2 :07 165 E 7 67 V.c 1 9 1, . ý I IDECp 8 1...WP.T. SASKATOIEAN4 p11100 i8-t976 a $lueLye$ C429 ,"omber 197r ILOCA&130N 𔃾S 26 WIN7 40 9LX 184 1Im AN ISO US00 AW CLMATIC. BRE- --- L ItI of. o4 U1 99...JUN 62 45 33 14 4.1 3.1 57 W 7 55 8583 . 9003 1 014621 JUL 78 50 3725 3.0.0 _# #W 7 477972 35.21900 5 20 0 010153 5 0 6 AUG72 -318 5.3 4.9 1 4W 7 47875

Elongate summit calderas as Neogene paleostress indicators in Antarctica

USGS Publications Warehouse

Paulsen, T.S.; Wilson, T.J.

2007-01-01

The orientations and ages of elongate summit calderas on major polygenetic volcanoes were compiled to document Miocene to Pleistocene Sh (minimum horizontal stress) directions on the western and northern flanks of the West Antarctic rift system. Miocene to Pleistocene summit calderas along the western Ross Sea show relatively consistent ENE long axis trends, which are at a high angle to the Transantarctic Mountain Front and parallel to the N77ºE Sh direction at Cape Roberts. The elongation directions of many Miocene to Pleistocene summit calderas in Marie Byrd Land parallel the alignment of polygenetic volcanoes in which they occur, except several Pleistocene calderas with consistent NNE to NE trends. The overall pattern of elongate calderas in Marie Byrd Land is probably due to a combination of structurally controlled orientations and regional stress fields in which Sh is oriented NNE to NE at a moderate to high angle to the trace of the West Antarctic rift system.

Improvement of Managerial Education of Junior Officers of the Venezuelan Navy.

DTIC Science & Technology

1988-03-01

it is very important that the Navy has a well rounded career program to improve the management education of all officers, especially for those just...93943-5100 5. Comandancia General de la Armada de Venezuela 2 Director de Educacion de la Armada Ave. Vollmer, San Bernardino Caracas, Venezuela 1011...6. Escuela Superior de Guerra Naval 1 Direccion de Educacion de la Armada Ave. Vollmer, San Bernardino Caracas, Venezuela 1011 7. Cdr. Igor A. Campos

Effect of Two-Way Air-Sea Coupling in High and Low Wind Speed Regimes

DTIC Science & Technology

2010-09-01

testing determined, however, that using a separate dynamical framework for the ocean model produced better results, primarily because it allowed for a...author address: Sue Chen, Naval Research Lab- oratory, 7 Grace Hopper Ave., Stop 2, Monterey, CA 93943-5502. E-mail: sue.chen@nrlmry.navy.mil 1 COAMPS is...ORGANIZATION NAME(S) AND ADDRESS(ES) Naval Research Laboratory,7 Grace Hopper Ave., Stop 2,Monterey, CA ,93943-5502 8. PERFORMING ORGANIZATION REPORT NUMBER 9

Ensemble-based prediction of RNA secondary structures.

PubMed

Aghaeepour, Nima; Hoos, Holger H

2013-04-24

Accurate structure prediction methods play an important role for the understanding of RNA function. Energy-based, pseudoknot-free secondary structure prediction is one of the most widely used and versatile approaches, and improved methods for this task have received much attention over the past five years. Despite the impressive progress that as been achieved in this area, existing evaluations of the prediction accuracy achieved by various algorithms do not provide a comprehensive, statistically sound assessment. Furthermore, while there is increasing evidence that no prediction algorithm consistently outperforms all others, no work has been done to exploit the complementary strengths of multiple approaches. In this work, we present two contributions to the area of RNA secondary structure prediction. Firstly, we use state-of-the-art, resampling-based statistical methods together with a previously published and increasingly widely used dataset of high-quality RNA structures to conduct a comprehensive evaluation of existing RNA secondary structure prediction procedures. The results from this evaluation clarify the performance relationship between ten well-known existing energy-based pseudoknot-free RNA secondary structure prediction methods and clearly demonstrate the progress that has been achieved in recent years. Secondly, we introduce AveRNA, a generic and powerful method for combining a set of existing secondary structure prediction procedures into an ensemble-based method that achieves significantly higher prediction accuracies than obtained from any of its component procedures. Our new, ensemble-based method, AveRNA, improves the state of the art for energy-based, pseudoknot-free RNA secondary structure prediction by exploiting the complementary strengths of multiple existing prediction procedures, as demonstrated using a state-of-the-art statistical resampling approach. In addition, AveRNA allows an intuitive and effective control of the trade-off between

Kinematics of Late Cretaceous subduction initiation in the Neo-Tethys Ocean reconstructed from ophiolites of Turkey, Cyprus, and Syria

NASA Astrophysics Data System (ADS)

Maffione, Marco; van Hinsbergen, Douwe; de Gelder, Giovanni; van der Goes, Freek; Morris, Antony

2017-04-01

Formation of new subduction zones represents one of the cornerstones of plate tectonics, yet both the kinematics and geodynamics governing this process remain enigmatic. A major subduction initiation event occurred in the Late Cretaceous, within the Neo-Tethys Ocean between Gondwana and Eurasia. Supra-subduction zone (SSZ) ophiolites (i.e., emerged fragments of ancient oceanic lithosphere accreted at supra-subduction spreading centers) were generated during this subduction event, and are today distributed in the eastern Mediterranean region along three E-W trending ophiolitic belts. Current models associate these ophiolite belts to simultaneous initiation of multiple, E-W trending subduction zones at 95 Ma. Here we report paleospreading direction data obtained from paleomagnetic analysis of sheeted dyke sections from seven Neo-Tethyan ophiolites of Turkey, Cyprus, and Syria, demonstrating that these ophiolites formed at NNE-SSW striking ridges parallel to the newly formed subduction zones. This subduction system was step-shaped and composed of NNE-SSW and ESE-WNW segments. The eastern subduction segment invaded the SW Mediterranean, leading to a radial obduction pattern similar to the Banda arc. Emplacement age constraints indicate that this subduction system formed close to the Triassic passive and paleo-transform margins of the Anatolide-Tauride continental block. Because the original Triassic-Jurassic Neo-Tethyan spreading ridge must have already subducted below the Pontides before the Late Cretaceous, we infer that the Late Cretaceous Neo-Tethyan subduction system started within ancient lithosphere, along NNE-SSW oriented fracture zones and faults parallel to the E-W trending passive margins. This challenges current concepts suggesting that subduction initiation occurs along active intra-oceanic plate boundaries.

Editorial Commentary: Hip Arthroscopy-Safe, Effective, and Still Improving in Older Nonarthritic Patients.

PubMed

Ortiz-Declet, Victor; Domb, Benjamin G

2016-12-01

Hip arthroscopy in nonarthritic patients 60 or older has been increasingly reported in short-term outcome studies. The rise in hip-preservation operations in this population has been associated with encouraging improvements in patient-reported outcome scores. More stringent radiographic indications (at least 2 mm of joint space and Tönnis osteoarthritis grade ≤1) during patient selection have also yielded better outcomes. Delayed gadolinium-enhanced magnetic resonance imaging of cartilage is another tool that should be considered during preoperative planning. With improvements in preoperative workup, imaging, and surgical technique, we anticipate that hip arthroscopy will continue to show positive results in an older patient population when carefully selected. Copyright © 2016 Arthroscopy Association of North America. Published by Elsevier Inc. All rights reserved.

Importance of the What, When, and Where of Mosquito Collection Events

DTIC Science & Technology

2009-01-01

Division of Entomology , Walter Reed Army Institute of Research, 503 Robert Grant Ave., Silver Spring, MD 20910 J. Med. Entomol. 46(4): 717Ð722 (2009...Department of Defense. 1 Corresponding author, e-mail: foleydes@si.edu. 0022-2585/09/0717Ð0722$04.00/0 2009 Entomological Society of America Report...PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Walter Reed Army Institute of Research,Division of Entomology ,503 Robert Grant Ave,Silver Spring,MD,20910

Light extinction by fine atmospheric particles in the White Mountains region of New Hampshire and its relationship to air mass transport.

PubMed

Slater, John F; Dibb, Jack E; Keim, Barry D; Talbot, Robert W

2002-03-27

Chemical, optical, and physical measurements of fine aerosols (aerodynamic diameter < or = 2.5 microm) have been performed at a mountaintop location adjacent to the White Mountain National Forest in northern NH, USA. A 1-month long sampling campaign was conducted at Cranmore Mountain during spring 2000. We report on the apportionment of light extinction by fine aerosols into its major chemical components, and relationships between variations in aerosol parameters and changes in air mass origin. Filter-based, 24-h integrated samples were collected and analyzed for major inorganic ions, as well as organic (OC), elemental (EC), and total carbon. Light scattering and light absorption coefficients were measured at 5-min intervals using an integrating nephelometer and a light absorption photometer. Fine particle number density was measured with a condensation particle counter. Air mass origins and transport patterns were investigated through the use of 3-day backward trajectories and a synoptic climate classification system. Two distinct transport regimes were observed: (1) flow from the north/northeast (N/NE) occurred during 9 out of 18 sample-days; and (2) flow from the west/southwest (W/SW) occurred 8 out of 18 sample-days. All measured and derived aerosol and meteorological parameters were separated into two categories based on these different flow scenarios. During W/SW flow, higher values of aerosol chemical concentration, absorption and scattering coefficients, number density, and haziness were observed compared to N/NE flow. The highest level of haziness was associated with the climate classification Frontal Atlantic Return, which brought polluted air into the region from the mid-Atlantic corridor. Fine particle mass scattering efficiencies of (NH4)2SO4 and OC were 5.35 +/- 0.42 m2 g(-1) and 1.56 +/- 0.40 m2 g(-1), respectively, when transport was out of the N/NE. When transport was from the W/SW the values were 4.94 +/- 0.68 m2 g(-1) for (NH4)2SO4 and 2.18 +/- 0

Conserved and divergent expression patterns of markers of axial development in the laboratory opossum, Monodelphis domestica.

PubMed

Yoshida, Michio; Kajikawa, Eriko; Yamamoto, Daisuke; Kurokawa, Daisuke; Yonemura, Shigenobu; Kobayashi, Kensaku; Kiyonari, Hiroshi; Aizawa, Shinichi

2016-12-01

Previous comparative studies suggest that the requirement for Nodal in epiblast and hypoblast development is unique to mammalians. Expression of anterior visceral endoderm (AVE) genes in the visceral endoderm and of their orthologs in the hypoblast may be unique to mammalians and avians, and is absent in the reptilian hypoblast. Axis formation in reptiles is signaled by the formation of the posterior marginal epiblast (PME), which expresses a series of primitive streak genes. To assess the phylogenetic origin of Nodal and AVE gene expression and axis formation in amniotes, we examined marker gene expression in gray short-tailed opossum, a metatherian. Nodal was expressed in neither epiblast nor hypoblast of opossum embryos. No AVE genes were expressed in the opossum hypoblast. Attainment of polarity in the embryonic disk was signaled by Nodal, Wnt3a, Fgf8, and Bra expression in the PME at 8.5 days post-coitus. Nodal expression in epiblast or hypoblast may be unique to eutherians. AVE gene expression in visceral endoderm and hypoblast may have been independently acquired in eutherian and avian lineages. PME formation appears to be the event that signals axis formation in reptilian and metatherian embryos, and thus may be an ancestral characteristic of basal amniotes. Developmental Dynamics 245:1176-1188, 2016. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

5. SITE OVERVIEW. DETAIL VIEW OF INTERCHANGE OF ARROYO SECO ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

5. SITE OVERVIEW. DETAIL VIEW OF INTERCHANGE OF ARROYO SECO PARKWAY AT RIGHT, INTERSTATE 1-5 AT CENTER, AND FIGUEROA STREET AT LEFT. NOTE ARROYO SECO CHANNEL PARALLEL TO PARKWAY. NOTE AVENUE 26 BRIDGE AT CENTER. LOOKING 30° NNE. - Arroyo Seco Parkway, Los Angeles to Pasadena, Los Angeles, Los Angeles County, CA

5. SOUTH SIDE DRIVE AT CHAPEL STRAIGHT. NOTE BIKE PATH ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

5. SOUTH SIDE DRIVE AT CHAPEL STRAIGHT. NOTE BIKE PATH AND BOULDER LANE EDGING. CHAPEL SPIRE AT CENTER. LOCATION OF OLD YOSEMITE VILLAGE AT CENTER DISTANCE. NORTH DOME AT REAR. LOOKING NNE. GIS: N-37 44 21.8 / W-119 35 39.3 - Yosemite National Park Roads & Bridges, Yosemite Village, Mariposa County, CA

Changes in Serum Electrolytes, Urea, and Creatinine in Aloe Vera-treated Rats

PubMed Central

Saka, WA; Akhigbe, RE; Popoola, OT; Oyekunle, OS

2012-01-01

This study was carried out to investigate the effect of Aloe vera extract (AvE) on serum electrolytes, urea, and creatinine as indices of renal function in Sprague-Dawley rats. Twelve male Sprague-Dawley rats weighing between 80 and 130 g were used. Rats were divided into two groups: The control and the test groups (n=6). The test group received 1 ml of AvE daily for 28 days. Both the groups fed on standard rat chow and water ad libitum. The results showed a decrease in serum levels of sodium, and potassium, but an increase in the serum levels of bicarbonate, urea, and creatinine in the test group. The changes seen were, however, statistically insignificant, except for the serum levels of sodium and creatinine (P<0.05). It is thus concluded that AvE impairs renal handling of electrolytes with consequent hyponatremia and hypercreatinemia. However, this might be of therapeutic value in conditions associated with hypernatremia. PMID:22754258

Sex differences of hip morphology in young adults with hip pain and labral tears.

PubMed

Hetsroni, Iftach; Dela Torre, Katrina; Duke, Gavin; Lyman, Stephen; Kelly, Bryan T

2013-01-01

To compare hip morphology between young men and women who presented with hip pain and labral tears. A retrospective review of our hip arthroscopy registry from March 2008 to June 2010 was completed. We identified 217 patients (249 hips) who were between the ages of 18 to 30 years. The inclusion criteria were (1) insidious-onset hip pain or worsening pain after low-energy sports trauma, (2) positive hip impingement sign, (3) Tönnis grades 0 to 1, (4) magnetic resonance imaging showing labral tear, and (5) primary hip arthroscopy confirming labral tear. Forty-five patients (52 hips) were excluded for the following reasons: (1) revision hip arthroscopy, (2) high-energy hip trauma, (3) history of surgery involving the femur or pelvis, (4) previous fractures of the femur or pelvis, (5) Tönnis grades 2 or above, (6) proliferative disease of the hip (i.e., synovial chondromatosis, pigmented villonodular synovitis), (7) neuromuscular disease (i.e., cerebral palsy), and (8) deformities related to Legg-Calvé-Perthes disease or developmental dysplasia of the hip. Therefore, the cohort study group included 105 (61%) men (123 [62.4%] hips) and 67 (39%) women (74 [37.6%] hips). Sex comparisons were made for the following variables measured on preoperative hip computed tomography scans: alpha angle, acetabular version, femoral version, lateral center-edge angle, and neck-shaft angle. Women had smaller alpha angles (47.8°v 63.6°, P < .001), increased acetabular version (17.3°v 13.9°, P < .001), and increased femoral anteversion (14.4°v 12.1°, P = .05). In young adults with hip pain and labral tears, women have smaller alpha angles and hips that are generally more anteverted. Therefore, in women, cam lesions may be more subtle, preoperative hip version analyses should be encouraged, and rim trimming may need to be cautiously planned to avoid increasing contact stresses at weight-bearing areas after such a procedure. Level III, retrospective comparative study. Copyright �

Exploring the feasibility of smart phone microphone for measurement of acoustic voice parameters and voice pathology screening.

PubMed

Uloza, Virgilijus; Padervinskis, Evaldas; Vegiene, Aurelija; Pribuisiene, Ruta; Saferis, Viktoras; Vaiciukynas, Evaldas; Gelzinis, Adas; Verikas, Antanas

2015-11-01

The objective of this study is to evaluate the reliability of acoustic voice parameters obtained using smart phone (SP) microphones and investigate the utility of use of SP voice recordings for voice screening. Voice samples of sustained vowel/a/obtained from 118 subjects (34 normal and 84 pathological voices) were recorded simultaneously through two microphones: oral AKG Perception 220 microphone and SP Samsung Galaxy Note3 microphone. Acoustic voice signal data were measured for fundamental frequency, jitter and shimmer, normalized noise energy (NNE), signal to noise ratio and harmonic to noise ratio using Dr. Speech software. Discriminant analysis-based Correct Classification Rate (CCR) and Random Forest Classifier (RFC) based Equal Error Rate (EER) were used to evaluate the feasibility of acoustic voice parameters classifying normal and pathological voice classes. Lithuanian version of Glottal Function Index (LT_GFI) questionnaire was utilized for self-assessment of the severity of voice disorder. The correlations of acoustic voice parameters obtained with two types of microphones were statistically significant and strong (r = 0.73-1.0) for the entire measurements. When classifying into normal/pathological voice classes, the Oral-NNE revealed the CCR of 73.7% and the pair of SP-NNE and SP-shimmer parameters revealed CCR of 79.5%. However, fusion of the results obtained from SP voice recordings and GFI data provided the CCR of 84.60% and RFC revealed the EER of 7.9%, respectively. In conclusion, measurements of acoustic voice parameters using SP microphone were shown to be reliable in clinical settings demonstrating high CCR and low EER when distinguishing normal and pathological voice classes, and validated the suitability of the SP microphone signal for the task of automatic voice analysis and screening.

Fault-Slip Data Analysis and Cover Versus Basement Fracture Patterns - Implications for Subsurface Technical Processes in Thuringia, Germany

NASA Astrophysics Data System (ADS)

Kasch, N.; Kley, J.; Navabpour, P.; Siegburg, M.; Malz, A.

2014-12-01

Recent investigations in Thuringia, Central Germany, focus on the potential for carbon sequestration, groundwater supply and geothermal energy. We report on the results of an integrated fault-slip data analysis to characterize the geometries and kinematics of systematic fractures in contrasting basement and cover rock lithologies. The lithostratigraphy of the area comprises locally exposed crystalline rocks and intermittently overlying Permian volcanic and clastic sedimentary rocks, together referred to as basement. A Late Permian sequence of evaporites, carbonates and shale constitutes the transition to the continuous sedimentary cover of Triassic age. Major NW-SE-striking fault zones and minor NNE-SSW-striking faults affect this stratigraphic succession. These characteristic narrow deforming areas (< 3 km width) build a dense network of individual fault strands with a close juxtaposition to wider (> 15 km) non-deforming areas suggesting localized zones of mechanical weakness, which can be confirmed by the frequent reactivation of single fault strands. Along the major fault zones, the basement and cover contain dominant inclined to sub-vertical NW-SE-striking fractures. These fractures indicate successive normal, dextral strike-slip and reverse senses of slip, evidencing events of NNE-SSW extension and contraction. Another system of mostly sub-vertical NNW-SSE- and NE-SW-striking conjugate strike-slip faults mainly developed within the cover implies NNE-SSW contraction and WNW-ESE extension. Earthquake focal mechanisms and in-situ stress measurements reveal a NW-SE trend for the modern SHmax. Nevertheless, fractures and fault-slip indicators are rare in the non-deforming areas, which characterizes Thuringia as a dual domain of (1) large unfractured areas and (2) narrow zones of high potential for technical applications. Our data therefore provide a basis for estimation of slip and dilation tendency of the contrasting fractures in the basement and cover under the

Cenozoic tectonic events at the border of the Paraná Basin, São Paulo, Brazil

NASA Astrophysics Data System (ADS)

Fernandes, A. J.; Amaral, G.

2002-03-01

In the last decade, even in areas that had been considered tectonically stable, a great amount of Cenozoic, including the Quaternary period, structural data have been collected throughout Brazil. The main goal of this study is to describe the Cenozoic structures and tectonic evolution of an area that is located at the border of the Paraná Basin in the state of São Paulo. The research methods consisted of the analysis of: (1) brittle structure data, mainly conjugate fractures and fault slip data; (2) lineaments traced on air photos and TM Landsat and radar images; and (3) a second-order base surface map. The study area, during the Cenozoic, has been affected by five strike-slip tectonic events, which generated mainly strike-slip faults, and secondarily normal and reverse ones. The events were named, from the oldest to the youngest, E1-NE, E2-EW, E3-NW, E4-NS, and E5-NNE; and the maximum principal stresses σ1 strike approximately NE-SW, E-W, NW-SE, N-S, and NNE-SSW, respectively. Event E2-EW seems to have been contemporaneous with the deposition of the Rio Claro Formation, the most important Cenozoic deposit of probable Neogenic age, and also to have controlled the distribution of its deposits. Event E3-NW was the strongest one in the area, as is pointed out by structural data, and the maximum principal stress σ1 of event E5-NNE is partially concordant with the orientation of σH-max of well break-out data in the Paraná Basin, suggesting a Neotectonic activity for this event. Finally, discontinuities parallel and correlated to the directions of strike-slip faults of the Cenozoic events seem to have actively controlled the sculpturing of the relief in the study area.

Analysis of ERTS-1 linear features in New York State

NASA Technical Reports Server (NTRS)

Isachsen, Y. W. (Principal Investigator); Fakundiny, R. H.; Forster, S. W.

1974-01-01

The author has identified the following significant results. All ERTS-1 linears confirmed to date have topographic expression although they may appear as featureless tonal linears on the imagery. A bias is unavoidably introduced against any linears which may parallel raster lines, lithological trends, or the azimuth of solar illumination. Ground study of ERTS-1 topographic lineaments in the Adirondacks indicates: outcrops along linears are even more rare than expected, fault breccias are found along some NNE lineaments, chloritization and slickensiding without brecciation characterize one EW lineament whereas closely-spaced jointing plus a zone of plastic shear define another. Field work in the Catskills suggests that the prominent new NNE lineaments may be surface manifestations of normal faulting in the basement, and that it may become possible to map major joint sets over extensive plateau regions directly on the imagery. Fall and winter images each display some unique linears, and long linears on the fall image commonly appear as aligned segments on the winter scene. A computer-processed color composite image permitted the extraction or additional information on the shaded side of mountains.

Design, Development and Pre-Flight Testing of the Communications, Navigation, and Networking Reconfigurable Testbed (Connect) to Investigate Software Defined Radio Architecture on the International Space Station

NASA Technical Reports Server (NTRS)

Over, Ann P.; Barrett, Michael J.; Reinhart, Richard C.; Free, James M.; Cikanek, Harry A., III

2011-01-01

The Communication Navigation and Networking Reconfigurable Testbed (CoNNeCT) is a NASA-sponsored mission, which will investigate the usage of Software Defined Radios (SDRs) as a multi-function communication system for space missions. A softwaredefined radio system is a communication system in which typical components of the system (e.g., modulators) are incorporated into software. The software-defined capability allows flexibility and experimentation in different modulation, coding and other parameters to understand their effects on performance. This flexibility builds inherent redundancy and flexibility into the system for improved operational efficiency, real-time changes to space missions and enhanced reliability/redundancy. The CoNNeCT Project is a collaboration between industrial radio providers and NASA. The industrial radio providers are providing the SDRs and NASA is designing, building and testing the entire flight system. The flight system will be integrated on the Express Logistics Carrier (ELC) on the International Space Station (ISS) after launch on the H-IIB Transfer Vehicle in 2012. This paper provides an overview of the technology research objectives, payload description, design challenges and pre-flight testing results.

Automated Visual Event Detection, Tracking, and Data Management System for Cabled- Observatory Video

NASA Astrophysics Data System (ADS)

Edgington, D. R.; Cline, D. E.; Schlining, B.; Raymond, E.

2008-12-01

Ocean observatories and underwater video surveys have the potential to unlock important discoveries with new and existing camera systems. Yet the burden of video management and analysis often requires reducing the amount of video recorded through time-lapse video or similar methods. It's unknown how many digitized video data sets exist in the oceanographic community, but we suspect that many remain under analyzed due to lack of good tools or human resources to analyze the video. To help address this problem, the Automated Visual Event Detection (AVED) software and The Video Annotation and Reference System (VARS) have been under development at MBARI. For detecting interesting events in the video, the AVED software has been developed over the last 5 years. AVED is based on a neuromorphic-selective attention algorithm, modeled on the human vision system. Frames are decomposed into specific feature maps that are combined into a unique saliency map. This saliency map is then scanned to determine the most salient locations. The candidate salient locations are then segmented from the scene using algorithms suitable for the low, non-uniform light and marine snow typical of deep underwater video. For managing the AVED descriptions of the video, the VARS system provides an interface and database for describing, viewing, and cataloging the video. VARS was developed by the MBARI for annotating deep-sea video data and is currently being used to describe over 3000 dives by our remotely operated vehicles (ROV), making it well suited to this deepwater observatory application with only a few modifications. To meet the compute and data intensive job of video processing, a distributed heterogeneous network of computers is managed using the Condor workload management system. This system manages data storage, video transcoding, and AVED processing. Looking to the future, we see high-speed networks and Grid technology as an important element in addressing the problem of processing and

Dosimetric comparison of lung stereotactic body radiotherapy treatment plans using averaged computed tomography and end-exhalation computed tomography images: Evaluation of the effect of different dose-calculation algorithms and prescription methods

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mitsuyoshi, Takamasa; Nakamura, Mitsuhiro, E-mail: m_nkmr@kuhp.kyoto-u.ac.jp; Matsuo, Yukinori

The purpose of this article is to quantitatively evaluate differences in dose distributions calculated using various computed tomography (CT) datasets, dose-calculation algorithms, and prescription methods in stereotactic body radiotherapy (SBRT) for patients with early-stage lung cancer. Data on 29 patients with early-stage lung cancer treated with SBRT were retrospectively analyzed. Averaged CT (Ave-CT) and expiratory CT (Ex-CT) images were reconstructed for each patient using 4-dimensional CT data. Dose distributions were initially calculated using the Ave-CT images and recalculated (in the same monitor units [MUs]) by employing Ex-CT images with the same beam arrangements. The dose-volume parameters, including D{sub 95}, D{submore » 90}, D{sub 50}, and D{sub 2} of the planning target volume (PTV), were compared between the 2 image sets. To explore the influence of dose-calculation algorithms and prescription methods on the differences in dose distributions evident between Ave-CT and Ex-CT images, we calculated dose distributions using the following 3 different algorithms: x-ray Voxel Monte Carlo (XVMC), Acuros XB (AXB), and the anisotropic analytical algorithm (AAA). We also used 2 different dose-prescription methods; the isocenter prescription and the PTV periphery prescription methods. All differences in PTV dose-volume parameters calculated using Ave-CT and Ex-CT data were within 3 percentage points (%pts) employing the isocenter prescription method, and within 1.5%pts using the PTV periphery prescription method, irrespective of which of the 3 algorithms (XVMC, AXB, and AAA) was employed. The frequencies of dose-volume parameters differing by >1%pt when the XVMC and AXB were used were greater than those associated with the use of the AAA, regardless of the dose-prescription method employed. All differences in PTV dose-volume parameters calculated using Ave-CT and Ex-CT data on patients who underwent lung SBRT were within 3%pts, regardless of the dose

Exploring the potential of [11C]choline-PET/CT as a novel imaging biomarker for predicting early treatment response in prostate cancer.

PubMed

Challapalli, Amarnath; Barwick, Tara; Tomasi, Giampaolo; O' Doherty, Michael; Contractor, Kaiyumars; Stewart, Simon; Al-Nahhas, Adil; Behan, Kevin; Coombes, Charles; Aboagye, Eric O; Mangar, Stephen

2014-01-01

The aim of the study was to assess the effects of neoadjuvant androgen deprivation (NAD) and radical prostate radiotherapy with concurrent androgen deprivation (RT-CAD) on prostatic [C]choline kinetics and thus develop methodology for the use of [C]choline-PET/computed tomography (CT) as an early imaging biomarker. Ten patients with histologically confirmed prostate cancer underwent three sequential dynamic [C]choline-PET/CT pelvic scans: at baseline, after NAD and 4 months after RT-CAD. [C]Choline uptake was quantified using the average and maximum standardized uptake values at 60 min (SUV60,ave and SUV60,max), the tumour-to-muscle ratios (TMR60,max) and net irreversible retention of [C]choline at steady state (Kimod-pat). The combination of NAD and RT-CAD significantly decreased tumour [C]choline uptake (SUV60,ave, SUV60,max, TMR60,max or Kimod-pat) and prostate-specific antigen (PSA) levels (analysis of variance, P<0.001 for all variables). Although the magnitude of reduction in the variables was larger after NAD, there was a smaller additional reduction after RT-CAD. A wide range of reduction in tumour SUV60,ave (38-83.7%) and SUV60,max (22.2-85.3%) was seen with combined NAD and RT-CAD despite patients universally achieving PSA suppression (narrow range of 93.5-99.7%). There was good association between baseline SUV60,max and initial PSA levels (Pearson's r=0.7, P=0.04). The reduction in tumour SUV60,ave after NAD was associated with PSA reduction (r=0.7, P=0.04). This association occurred despite the larger reduction in PSA (94%) compared with SUV60,ave (58%). This feasibility study shows that [C]choline-PET/CT detects metabolic changes within tumours following NAD and RT-CAD to the prostate. A differential reduction in [C]choline uptake despite a global reduction in PSA following NAD and RT-CAD could provide prognostic information and warrants further evaluation as an imaging biomarker in this setting.

Borehole breakout orientation from LWD data (IODP Exp. 334) and the present stress state in the Costa Rica Seismogenesis Project transect

NASA Astrophysics Data System (ADS)

Malinverno, A.; Saito, S.

2013-12-01

water depth). The maximum principal horizontal stress is directed NNE-SSW at Site U1378 and WSW-ENE at Site U1379. These directions are approximately parallel and perpendicular to NNE-directed GPS deformation vectors on land. On erosive convergent margins, a transition is expected to take place from a compressive regime near a frontal wedge to extension and subsidence moving landward of the deformation front. Our working hypothesis is that this transition may take place between Sites U1378, where the breakout orientation is consistent with NNE-SSW compression, and Site U1379, where the breakouts indicate NNE-SSW extension.

Improvement of a mixture experiment model relating the component proportions to the size of nanonized itraconazole particles in extemporary suspensions

DOE PAGES

Pattarino, Franco; Piepel, Greg; Rinaldi, Maurizio

2018-03-03

A paper by Foglio Bonda et al. published previously in this journal (2016, Vol. 83, pp. 175–183) discussed the use of mixture experiment design and modeling methods to study how the proportions of three components in an extemporaneous oral suspension affected the mean diameter of drug particles (Z ave). The three components were itraconazole (ITZ), Tween 20 (TW20), and Methocel® E5 (E5). This commentary addresses some errors and other issues in the previous paper, and also discusses an improved model relating proportions of ITZ, TW20, and E5 to Z ave. The improved model contains six of the 10 terms inmore » the full-cubic mixture model, which were selected using a different cross-validation procedure than used in the previous paper. In conclusion, compared to the four-term model presented in the previous paper, the improved model fit the data better, had excellent cross-validation performance, and the predicted Z ave of a validation point was within model uncertainty of the measured value.« less

Improvement of a mixture experiment model relating the component proportions to the size of nanonized itraconazole particles in extemporary suspensions.

PubMed

Pattarino, Franco; Piepel, Greg; Rinaldi, Maurizio

2018-05-30

A paper by Foglio Bonda et al. published previously in this journal (2016, Vol. 83, pp. 175-183) discussed the use of mixture experiment design and modeling methods to study how the proportions of three components in an extemporaneous oral suspension affected the mean diameter of drug particles (Z ave ). The three components were itraconazole (ITZ), Tween 20 (TW20), and Methocel® E5 (E5). This commentary addresses some errors and other issues in the previous paper, and also discusses an improved model relating proportions of ITZ, TW20, and E5 to Z ave . The improved model contains six of the 10 terms in the full-cubic mixture model, which were selected using a different cross-validation procedure than used in the previous paper. Compared to the four-term model presented in the previous paper, the improved model fit the data better, had excellent cross-validation performance, and the predicted Z ave of a validation point was within model uncertainty of the measured value. Copyright © 2018 Elsevier B.V. All rights reserved.

Improvement of a mixture experiment model relating the component proportions to the size of nanonized itraconazole particles in extemporary suspensions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pattarino, Franco; Piepel, Greg; Rinaldi, Maurizio

A paper by Foglio Bonda et al. published previously in this journal (2016, Vol. 83, pp. 175–183) discussed the use of mixture experiment design and modeling methods to study how the proportions of three components in an extemporaneous oral suspension affected the mean diameter of drug particles (Z ave). The three components were itraconazole (ITZ), Tween 20 (TW20), and Methocel® E5 (E5). This commentary addresses some errors and other issues in the previous paper, and also discusses an improved model relating proportions of ITZ, TW20, and E5 to Z ave. The improved model contains six of the 10 terms inmore » the full-cubic mixture model, which were selected using a different cross-validation procedure than used in the previous paper. In conclusion, compared to the four-term model presented in the previous paper, the improved model fit the data better, had excellent cross-validation performance, and the predicted Z ave of a validation point was within model uncertainty of the measured value.« less

Spreading Depolarizations Have Prolonged Direct Current Shifts and Are Associated with Poor Outcome in Brain Trauma

DTIC Science & Technology

2011-01-01

prognosis. Keywords: cortical spreading depression; electroencephalography; craniotomy ; signal processing; acute brain injury Introduction Cortical...Mannheim, Germany). Inclusion criteria were the clinical decision for craniotomy for lesion evacuation and/or decompression and age ~ 18 years...externalized through a burr hole in the skull (if the bone flap was replaced) and tu nne lied beneath the scalp to exit 2-3 em from the craniotomy

Federal Logistics Information System (FLIS) Procedures Manual. Volume 5: Data Bank Interrogations/Search.

DTIC Science & Technology

1995-04-01

NO. 5 DoD 4100.39-M D oD 4100.39-MN Volume 5 DLSC- VPH 1 January 1997 "N FEDERAL LOGISTICS INFORMATION SYSTEM (FLIS) PROCEDURES MANUAL I. Volume 5. DoD...LOGISTICS SERVICES CENTER 74 WASHINGTON AVE N BATTLE CREEK MI 49017-3084 CH 4 CHANGE NO. 4 DoD 4100.39-M DoD 4100.39-M Volume 5 DLSC- VPH 1 July 1996 "FEDERAL...CENTER Volume 5 74 WASHINGTON AVE N BATTLE CREEK, MI 49017-3084 DLSC- VPH 1 April 1995 FOREWORD This is one of the volumes (see backside of cover for

Moisture processes accompanying convective activity

NASA Technical Reports Server (NTRS)

Sienkiewicz, M. E.; Scoggins, J. R.

1982-01-01

A moisture budget analysis was performed on data collected during the AVE 7 (May 2 to 3, 1978) and AVE-SESAME1 (April 10 to 11, 1979) experiments. Local rates-of-change of moisture were compared with average moisture divergence in the same time period. Results were presented as contoured plots in the horizontal and as vertical cross sections. These results were used to develop models of the distribution of moisture processes in the vicinity of convective areas in two layers representing lower and middle tropospheric conditions. Good correspondence was found between the residual term of the moisture budget and actual precipitation.

Iron-absorption band analysis for the discrimination of iron-rich zones

NASA Technical Reports Server (NTRS)

Rowan, L. C. (Principal Investigator)

1973-01-01

The author has identified the following significant results. Lineament analysis of the area was initiated on individual images and then expanded areally by the use of mosaics at the 1:1,000,000 scale. Principal trends are NE, NW, NNE-NNW, and ENE. Several previously unrecognized lineaments are mapped which may be the surface manifestations of major fault or fracture zones. Three lineaments are especially noteworthy. Two of these, the Walker Lane and the Midas Trench lineament system, transect the prediominantly NNE-NNW trending mountain ranges for more than 500 km. A third major lineament, formed by the alinement of several topographic escarpments 10-20 km long, is orthogonal to the Midas Trench lineament. This lineament is marked by a distinct positive magnetic anomaly for approximately 200 km. Further visual analysis of ERTS-1 images has resulted in the delineation of 50 circular or elliptical features which are presumed to be volcanic or intrusive centers. A comparison with the 78 Tertiary volcanic centers mapped in the study area in 1970 indicates some good agreement between the proposed and known volcanic centers. The coincidence of some major lineaments and productive ore bodies implies a genetic relationship.

Tectonic evolution of the Neoproterozoic Tandilia sedimentary cover, Argentina: New evidence of contraction and extensional events in the southwest Gondwana margin

NASA Astrophysics Data System (ADS)

Hernández, Mariano; Arrouy, María Julia; Scivetti, Nicolás; Franzese, Juan R.; Canalicchio, José M.; Poiré, Daniel G.

2017-11-01

At the northwestern portion of the Tandilia System, a detailed structural analysis on the Precambrian sedimentary units exposed in the quarries of the Olavarría-Sierras Bayas area was carried out. These units exhibit deformational structures of several scales, from centimeters to hundreds of meters. The hundreds of meters scale involves E-W- and NW-SE-trending normal faults and NW-SE- and NE-SW-trending contractional folds. The centimeters to meters scale involves veins, joints, normal faults, shear fractures and stylolites, with a prevailing ∼ E-W to NW-SE trend. All these structures were formed by two major tectonic events. The first was the folding event at ∼580 Ma, with NNE-SSW to NE-SW and NW-SE direction of contraction. The second was the extensional faulting event, given by the widespread NNE-SSW-directed extension event during the Atlantic Ocean opening (Jurassic-Cretaceous). Both major events would have been controlled by the reactivation of basement anisotropies. These major tectonic events controlled the deformation of the Precambrian sedimentary cover of the Tandilia system, leading to an economically important aspect in the mining development of the Olavarría-Sierras Bayas area.

Effectiveness of Nutrition Education vs. Non-Nutrition Education Intervention in Improving Awareness Pertaining Iron Deficiency among Anemic Adolescents.

PubMed

Yusoff, Hafzan; Wan Daud, Wan Nudri; Ahmad, Zulkifli

2013-01-01

This study was carried out to compare the effect between nutrition education intervention and non-nutrition education intervention on awareness regarding iron deficiency among schooling adolescents in Tanah Merah, one of rural district in Kelantan, Malaysia. This study which was started in year 2010 involved 280 respondents (223 girls, 57 boys, age: 16 yr) from schools in Tanah Merah. The selection criteria were based on hemoglobin level (Hb = 7 - 11.9 g/dL for girls; Hb = 7 - 12.9 g/dL for boys). They were divided into 2 groups. The first group received nutrition education package (Nutrition education, NE), whereas another group was entitled to receive non-nutrition education intervention (Non-Nutrition Education, NNE) (supplement only). Both interventions were implemented for 3 months. The changes in awareness among respondents of both groups were evaluated using multi-choices questionnaire. Nutrition education receiver group (NE) demonstrated improvement in awareness at post-intervention. No substantial improvement was demonstrated by the counterpart group (NNE). Multimedia nutrition education program conducted at school setting was in fact practical and effective in improving awareness on iron deficiency among anemic adolescents.

Deformation style of the Mesozoic sedimentary rocks in southern Thailand

NASA Astrophysics Data System (ADS)

Kanjanapayont, Pitsanupong

2014-10-01

Mesozoic sedimentary rocks in southern Thailand are widespread from NNE-SSW and N-S in Chumphon and Trang provinces. The Mesozoic stratigraphic units are the marine Triassic Sai Bon Formation and the non-marine Jurassic-Cretaceous Thung Yai Group, the latter subdivided into Khlong Min, Lam Thap, Sam Chom, and Phun Phin Formations. These units overlie Permian carbonate rocks with an angular unconformity, and are overlain unconformably by Cenozoic units and the Quaternary sediments. The Mesozoic rocks have been folded to form two huge first-ordered syncline or synclinoria, the Chumphon and Surat Thani-Krabi-Trang synclinoria. These synclinoria are elongated in NNE-SSW to N-S direction, and incorporate asymmetric lower-order parasitic folds. The folds have moderately to steeply dipping eastward limbs and more gently dipping westward limbs. These folds were transected by brittle fractures in four major directions. These geologic structures indicate WNW-ESE to E-W contraction with top-to-the-east simple shear at some time before the deposition of the Cenozoic sedimentary units. No major deformation has affected the rocks subsequently, apart from the formation of the fault-controlled Cenozoic basins.

American woodcock (Scolopax minor) mortality associated with a reovirus

USGS Publications Warehouse

Docherty, D.E.; Converse, K.A.; Hansen, W.R.; Norman, G.W.

1994-01-01

A virus isolate associated with a 1989-90 die-off in American woodcock (Scolopax minor) was identified as a reovirus. Emaciation was a consistent necropsy finding in the woodcock involved in this die-off. This reovirus infection appeared to be systemic, had the potential for fecal-oral virus transmission, and was associated with deterioration of body condition. To our knowledge this is the first report of a virus isolate from wild American woodcock. A survey conducted in 1990-92 indicated that this virus was not present at detectable levels in the woodcock breeding and wintering population. /// Un virus asociado con la mortalidad de becadas o perdices americanas (Scolopax minor) en 1989-1990-fue identificado como reovirus. La emaciaci??n fue un resultado com??n a la necropsia de las aves que murieron. Esta infecci??n por reovirus pareci?? ser sist??mica, ten?-a el potencial de transmisi??n fecal-oral y estuvo asociada con el deterioro del ave. Creemos que este sea el primer reporte de aislamiento viral a partir de becadas americanas. Una encuesta hecha entre 1990 y 1992 indic?? que este virus no estaba presente en los niveles detectables en los reproductores y en las aves invernales.

Integrating water quality responses to best management practices in Portugal.

PubMed

Fonseca, André; Boaventura, Rui A R; Vilar, Vítor J P

2018-01-01

Nutrient nonpoint pollution has a significant impact on water resources worldwide. The main challenge of this work was to assess the application of best management practices in agricultural land to comply with water quality legislation for surface waters. The Hydrological Simulation Program-FORTRAN was used to evaluate water quality of Ave River in Portugal. Best management practices (infiltration basin) (BMP) were applied to agricultural land (for 3, 6, 9, 12, and 15% area) with removal efficiencies of 50% for fecal coliforms and 30% for nitrogen, phosphorus, and biochemical oxygen demand. The inflow of water quality constituents was reduced for all scenarios, with fecal coliforms achieving the highest reduction between 5.8 and 28.9% and nutrients and biochemical oxygen demand between 2 and 13%. Biochemical oxygen demand and orthophosphates concentrations achieved a good water quality status according to the European Legislation for scenarios of BMP applied to 3 and 12% agricultural area, respectively. Fecal coliform levels in Ave River basin require further treatment to fall below the established value in the abovementioned legislation. This study shows that agricultural watersheds such as Ave basins demand special attention in regard to nonpoint pollution sources effects on water quality and nutrient loads.

Does intraplate brittle deformation indicate far-field stress signals? A case study of Central Europe

NASA Astrophysics Data System (ADS)

Navabpour, Payman; Kley, Jonas; Le Breton, Eline; van Hinsbergen, Douwe J. J.; Ustaszewski, Kamil

2017-04-01

Even though Central Europe has been located within a plate interior since the end of the Variscan orogeny, its intracontinental basins and highs recorded a succession of different tectonic regimes throughout the Mesozoic and Cenozoic, which were coeval with events at distant plate margins. A long Triassic-Cretaceous period of weak subsidence with intermittent extension was followed by NNE-SSW contraction in the Late Cretaceous-Paleocene. Renewed extension led to the formation of the Cenozoic Rift System and eventually evolved to the present-day variable stress regimes with a consistent NW-SE-oriented maximum horizontal shortening, SHmax. The detailed knowledge of this evolution relies on exhaustive lithostratigraphy and geochronological datasets, as well as on reconstruction of successive states of paleostress that controlled the formation and/or inversion of intracontinental basins. In combination, these data provide an excellent opportunity of linking the intracontinental deformation to the lithospheric plate boundary kinematics. Regional-scale analysis of fault kinematics in Central Europe unveiled a succession of consistent stress states for the crystalline basement and sedimentary cover of the brittle crust. These states of stress include a post-Triassic normal faulting regime with NE-SW-trending σ3 axis, strike-slip and thrust faulting regimes with NNE-SSW-trending σ1 axis, supposedly of Late Cretaceous age, and two younger events of normal and strike-slip faulting regimes with NW-SE-trending σ3 and σ1 axes, respectively. In this study, we report on the first attempts of linking the central European intraplate kinematics to changes in relative motion between the plates. The integration of stress fields with plate boundary kinematics suggests that the Late Cretaceous contraction may be explained by a change in African plate motion with respect to Eurasia from SE-directed sinistral transform to NNE-directed convergence. The reorientation of contraction to

Mesozoic to Cenozoic tectonic transition process in Zhanhua Sag, Bohai Bay Basin, East China

NASA Astrophysics Data System (ADS)

Cheng, Yanjun; Wu, Zhiping; Lu, Shunan; Li, Xu; Lin, Chengyan; Huang, Zheng; Su, Wen; Jiang, Chao; Wang, Shouye

2018-04-01

The Zhanhua sag is part of the Bohai Bay intracontinental basin system that has developed since the Mesozoic in East China. The timing of this basin system coincides with the final assembly of East Asia and the development of Western Pacific-type plate margin. Here we use 3-D seismic and core log data to investigate the evolution of this basin and discuss its broad tectonic settings. Our new structural study of Zhanhua sag suggests that there are four major tectonic transitions occurred in the Bohai Bay Basin during Mesozoic and Cenozoic: (1) The first tectonic transition was from stable Craton to thrusting during the Triassic, mainly caused by the South China Block's subduction northward beneath the North China Block, which induced the formation of the NW-striking thrust faults. (2) The second tectonic transition was mainly characterized by a change from compression to extension, which can be further divided into two-stages. At the first stage, two episodes of NW-SE shortening occurred in East Asia during Early-Middle Jurassic and Late Jurassic-earliest Cretaceous, respectively. At the second stage, the extension and left-lateral shearing took place during Early Cretaceous while compression occurred during Late Cretaceous. The NW-striking thrust faults changed to normal faults and the NNE-striking left-lateral strike-slip faults started to influence the eastern part of the basin. (3) The third transition occurred when the NW-SE extension and NNE-striking right-lateral shearing started to form during Paleogene, and the peak deformation happen around 40 Ma due to the change of the subduction direction of Pacific Plate relative to Eurasia Plate. The NE-striking normal faults are the main structure, and the pre-existing NNE-striking strike-slip faults changed from left-lateral to right-lateral. (4) The fourth transition saw the regional subsidence during Neogene, which was probably caused by the India-Asia "Hard collision" between 25 and 20 Ma.

Evidences of a Lithospheric Fault Zone in the Sicily Channel Continental Rift (Southern Italy) from Instrumental Seismicity Data

NASA Astrophysics Data System (ADS)

Parisi, L.; Calo, M.

2013-12-01

The Sicily Channel continental rift is located in the African Plate and is submerged by a shallow sea extending from the northern coast of Africa to the southern coast of Sicily (southern Italy). The area is affected by an extensional regime since early Pliocene, which thins the continental crust and produces NW-SE oriented Pantelleria, Linosa and Malta grabens. The rift-related volcanic activity is represented by Pantelleria and Linosa Islands and a series of magmatic manifestations roughly NNE-SSW aligned, from Linosa Island to the Nameless Bank, in proximity of the Sicilian coast. Recent rapid magmatic ascents occurred along the strip near to the Sicilian coast in a region named Graham Bank. The NNE-SSW strip has already been recognised as a separation belt between the western sector of the rift (Pantelleria graben) and the eastern one (Linosa and Malta grabens). Seismic profiles suggest the presence of near vertical structures associated with strike slip fault zones. Bathymetric data show a 15-20 km wide zone characterised by several shallow basins irregularly alternated by topographic highs. However, evidences of a N-S or NNE-SSW orientated faults have not been found. In this work we re-localised the instrumental seismicity recorded between 1981 and 2012 in the Sicily Channel and western Sicily using the Double Difference method (Waldhauser, 2001, 2012) and 3D Vp and Vs models (Calò et al., 2013). The statistical analysis of the relocated seismicity together with the study of seismic energy release distribution allows us to describe the main patterns associated with the active faults in the western Sicily Straits. Here we find that most of the events in the Sicily Channel are highly clustered between 12.5°- 13.5°E and 35.5°-37°N with hypocentral depth between 5-40 km, reaching in some cases 70 km of depth. Seismic events seem to be aligned along a sub-vertical shear zone that is long at least 250 km and oriented approximately NNE-SSW. The spatial

Early Jurassic mafic dykes from the Xiazhuang ore district (South China): Implications for tectonic evolution and uranium metallogenesis

NASA Astrophysics Data System (ADS)

Wang, Lian-Xun; Ma, Chang-Qian; Lai, Zhong-Xin; Marks, Michael A. W.; Zhang, Chao; Zhong, Yu-Fang

2015-12-01

A comprehensive study on zircon U-Pb age dating, whole-rock geochemistry and Sr-Nd isotope data has been conducted on the mafic rocks of the Xiazhuang uranium ore district and adjacent regions in South China. Based on field work and petrographic features, three rock types (the Kuzhukeng gabbro, the WNW-trending dolerite dykes and the NNE-trending lamprophyre dykes) are distinguished. Early Jurassic SHRIMP and LA-ICPMS ages of zircon for the Kuzhukeng gabbro (198 ± 1 Ma) and WNW-trending dolerite dykes (193 ± 4 Ma) have been obtained, which are 50 Ma older than previously thought (being Cretaceous). These geochronologic data provide new evidence for the rarely identified Early Jurassic magmatisms in South China. Whole-rock geochemical data for the Kuzhukeng gabbro and WNW-trending dolerite dykes are similar, both of which being higher in FeO and TiO2 but lower in SiO2 and K2O than the NNE-trending lamprophyre dykes. Trace element characteristics and Sr-Nd isotope data indicate arc-like signatures similar to the Cretaceous southeast coast basalts of China for the lamprophyre dykes, but an OIB-like geochemical affinity for the high-TiO2 mafic rocks similar to the Permo/Triassic Emeishan flood basalts and the Middle Jurassic Ningyuan alkaline basalts. We propose that the lamprophyre dykes formed in an arc volcanic system driven by the subduction of the paleo-Pacific plate. In contrast, the Kuzhukeng gabbro and associated dolerite dykes record the post-orogenic (Indosinian) extension event in the Tethyan tectonic regime. This further implies that the Indosinian extension may have lasted until the Early Jurassic, and therefore, the subduction of the paleo-Pacific plate in south China was probably later than this period. Most U deposits of the Xiazhuang area are located at the intersection between the WNW-trending dolerite dykes and the NNE-trending faults within the Triassic granites of eastern Guidong complex, South China. Previous metallogenesis studies assumed that

Algorithms that Defy the Gravity of Learning Curve

DTIC Science & Technology

2017-04-28

three nearest neighbour-based anomaly detectors, i.e., an ensemble of nearest neigh- bours, a recent nearest neighbour-based ensemble method called iNNE...streams. Note that the change in sample size does not alter the geometrical data characteristics discussed here. 3.1 Experimental Methodology ...need to be answered. 3.6 Comparison with conventional ensemble methods Given the theoretical results, the third aim of this project (i.e., identify the

GRC GSFC TDRSS Waveform Metrics Report

NASA Technical Reports Server (NTRS)

Mortensen, Dale J.

2013-01-01

The report presents software metrics and porting metrics for the GGT Waveform. The porting was from a ground-based COTS SDR, the SDR-3000, to the CoNNeCT JPL SDR. The report does not address any of the Operating Environment (OE) software development, nor the original TDRSS waveform development at GSFC for the COTS SDR. With regard to STRS, the report presents compliance data and lessons learned.

Antiviral stockpiles for influenza pandemics from the household perspective: treatment alone versus treatment with prophylaxis.

PubMed

Kwok, Kin On; Leung, Gabriel M; Mak, Peter; Riley, Steven

2013-06-01

Model-based studies of antiviral use to mitigate the impact of moderate and severe influenza pandemics implicitly take the viewpoint of a central public health authority. However, it seems likely that the key decision of when to use antivirals will be made at the household level. We used a stochastic compartmental model of the transmission of influenza within and between households to evaluate the expected mortality under two strategies: households saving available antivirals for treatment only and households implementing prophylaxis as well as treatment. Given that every individual in the population was allocated a single course of antivirals, we investigated the impact of these two strategies for a wide range of AVED, the efficacy of antivirals in preventing death in severe cases (AVED=1 for complete protection). We found a cross-over point for our baseline parameter values in a regime where antivirals were still highly effective in reducing the chance of death: below AVED=0.9 the optimal strategy was for households to use both treatment and prophylaxis. We also considered the possibility that a small number of households might "cheat" by choosing to follow the treatment-only strategy when other households were following treatment with prophylaxis. The cross-over point for cheating households was considerably lower, at AVED=0.6, but substantially above 0. These results suggest that unless antivirals are almost completely effective in reducing the chance of death in serious cases, households will likely be better served implementing prophylaxis as well as treatment. More generally, our study illustrates the potential value of considering viewpoints other than a central authority when conducting model-based analysis of interventions against infectious disease. Copyright © 2013 Elsevier B.V. All rights reserved.

FMEA of manual and automated methods for commissioning a radiotherapy treatment planning system.

PubMed

Wexler, Amy; Gu, Bruce; Goddu, Sreekrishna; Mutic, Maya; Yaddanapudi, Sridhar; Olsen, Lindsey; Harry, Taylor; Noel, Camille; Pawlicki, Todd; Mutic, Sasa; Cai, Bin

2017-09-01

To evaluate the level of risk involved in treatment planning system (TPS) commissioning using a manual test procedure, and to compare the associated process-based risk to that of an automated commissioning process (ACP) by performing an in-depth failure modes and effects analysis (FMEA). The authors collaborated to determine the potential failure modes of the TPS commissioning process using (a) approaches involving manual data measurement, modeling, and validation tests and (b) an automated process utilizing application programming interface (API) scripting, preloaded, and premodeled standard radiation beam data, digital heterogeneous phantom, and an automated commissioning test suite (ACTS). The severity (S), occurrence (O), and detectability (D) were scored for each failure mode and the risk priority numbers (RPN) were derived based on TG-100 scale. Failure modes were then analyzed and ranked based on RPN. The total number of failure modes, RPN scores and the top 10 failure modes with highest risk were described and cross-compared between the two approaches. RPN reduction analysis is also presented and used as another quantifiable metric to evaluate the proposed approach. The FMEA of a MTP resulted in 47 failure modes with an RPN ave of 161 and S ave of 6.7. The highest risk process of "Measurement Equipment Selection" resulted in an RPN max of 640. The FMEA of an ACP resulted in 36 failure modes with an RPN ave of 73 and S ave of 6.7. The highest risk process of "EPID Calibration" resulted in an RPN max of 576. An FMEA of treatment planning commissioning tests using automation and standardization via API scripting, preloaded, and pre-modeled standard beam data, and digital phantoms suggests that errors and risks may be reduced through the use of an ACP. © 2017 American Association of Physicists in Medicine.

EFFICACY AND SAFETY OF A NEW TOPICAL TESTOSTERONE REPLACEMENT GEL THERAPY FOR THE TREATMENT OF MALE HYPOGONADISM.

PubMed

Cunningham, Glenn; Belkoff, Laurence; Brock, Gerald; Efros, Mitchell; Gittelman, Marc; Carrara, Dario; Neijber, Anders; Ando, Masakazu; Mitchel, Jules

2017-05-01

Testosterone replacement therapy is indicated for male hypogonadism. This study aimed to evaluate the efficacy and safety of testosterone gel 2% (Tgel) over 90 days. This phase 3, open-label, noncomparator study was conducted in adult hypogonadal men (2 consecutive fasting serum testosterone values <300 ng/dL and >86% subjects with symptoms consistent with testosterone deficiency). Subjects applied Tgel 23 mg/day (single pump-actuation using a hands-free cap applicator). The dose was uptitrated to 46 mg/day after 2 weeks if the 4-hour serum total testosterone level was <500 ng/dL. The dose could be further up- or downtitrated to 23, 46, and 69 mg on Days 21, 42, and 63. The primary endpoint included the percentage of subjects with average testosterone concentration (C ave (0-24) ) between 300 and 1,050 ng/dL on Day 90. Safety endpoints were adverse events (AEs), laboratory parameters, and vital signs. Of the 159 who enrolled, 139 men completed the study. Approximately three-quarters (76.1%) of subjects met C ave criteria on Day 90. Most AEs were mild to moderate. There were 5 serious AEs, and 1 (myocardial infarction) was judged as possibly related to Tgel. Confirmed excessive increases in prostate-specific antigen or hematocrit levels were rare. Tgel had a favorable local skin tolerability profile. Overall, 76% of subjects achieved C ave between 300 and 1,050 ng/dL with Tgel. Symptoms of testosterone deficiency improved with few safety concerns. AE = adverse event C ave(0-24) = average testosterone concentration CI = confidence interval C max = maximum concentration IIEF = International Index of Erectile Function MAF = Multidimensional Assessment of Fatigue PK = pharmacokinetic PSA = prostate-specific antigen SAE = serious adverse event SF-12 = Short Form 12 Health Survey Tgel = testosterone gel 2% T max = time to achieve maximum concentration TRT = testosterone replacement therapy.

78 FR 6806 - Forest Resource Coordinating Committee

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-31

...: Maya Solomon, 1400 Independence Ave. SW., mailstop 1123, Washington, DC 20250 or by email to... CONTACT: Maya Solomon, Forest Resource Coordinating Committee Program Coordinator, Cooperative Forestry...

77 FR 66865 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-07

... Williamson Rd. NE., Roanoke (Independent City), 12000968 Norfolk & Western Railway Freight Station, 303 Norfolk Ave., Roanoke (Independent City), 12000969 Rogers, Tayloe, House, 1542 Electric Rd., Roanoke...

Genome sizes of cranes (Aves: Gruiformes).

PubMed

Rasch, Ellen M

2006-12-01

The DNA content of blood cell nuclei of 15 species of cranes was determined by Feulgen-DNA cytophotometry. Genome sizes agree with values reported elsewhere for several crane species analyzed by flow cytometry. Males have more DNA per cell than females in several species. A karyotype where 2n = 80 is reported for a male greater sandhill crane. Copyright 2006 Wiley-Liss, Inc.

75 FR 76463 - Pesticide Products; Registration Applications

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-08

... Protection Agency, 1200 Pennsylvania Ave., NW., Washington, DC 20460-0001. SUPPLEMENTARY INFORMATION: I... calcium (calcium 3- oxido-5-oxo-4-propionylcyclohex-3-enecarboxylate). Proposed use: Sweet cherries...

75 FR 37384 - Application(s) for Duty-Free Entry of Scientific Instruments

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-29

..., semiconducting and magnetic nanosized materials and their assembled structures. Justification for Duty-Free Entry... California, Davis, One Shields Ave., Davis, CA 95616. Instrument: Electron Microscope. Manufacturer: Elionix...

78 FR 63571 - Advisory Council to the Internal Revenue Service; Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-24

... Hotel, 2430 Pennsylvania Ave. NW., Potomac Ballroom, Washington, DC 20036. Issues to be discussed... Clients that are Victims of Identity Theft, Guidance to Practitioners Regarding Professional Obligations...

Observations of SKS splitting beneath the Central and Southern External Dinarides in the Adria-Eurasia convergence zone

NASA Astrophysics Data System (ADS)

Subašić, Senad; Prevolnik, Snježan; Herak, Davorka; Herak, Marijan

2017-05-01

Seismic anisotropy beneath the greater region of the Central and Southern External Dinarides is estimated from observations of SKS splitting. The area is located in the broad and complex Africa-Eurasia convergent plate boundary zone, where the Adriatic microplate interacts with the Dinarides. We analyzed recordings of 12 broadband seismic stations located in the Croatian coastal region. Evidence of seismic anisotropy was found beneath all stations. Fast axis directions are oriented approximately in the NE-SW to NNE-SSW direction, perpendicularly to the strike of the Dinarides. Average delay times range between 0.6 and 1.0 s. A counter-clockwise rotation in average fast axis directions was observed for the stations in the northern part with respect to the stations in the southern part of the studied area. Fast axis directions coincide with the assumed direction of asthenospheric flow through a slab-gap below the Northern and Central External Dinarides, with the maximum tectonic stress orientation in the crust, and with fast directions of Pg and Sg-waves in the crust. These observations suggest that the detected SKS birefringence is primarily caused by the preferred lattice orientation of mantle minerals generated by the asthenospheric flow directed SW-NE to SSW-NNE, with a possible contribution from the crust.

Improved VAS regression soundings of mesoscale temperature structure observed during the 1982 atmospheric variability experiment

NASA Technical Reports Server (NTRS)

Chesters, Dennis; Keyser, Dennis A.; Larko, David E.; Uccellini, Louis W.

1987-01-01

An Atmospheric Variability Experiment (AVE) was conducted over the central U.S. in the spring of 1982, collecting radiosonde date to verify mesoscale soundings from the VISSR Atmospheric Sounder (VAS) on the GOES satellite. Previously published VAS/AVE comparisons for the 6 March 1982 case found that the satellite retrievals scarcely detected a low level temperature inversion or a mid-tropospheric cold pool over a special mesoscale radiosonde verification network in north central Texas. The previously published regression and physical retrieval algorithms did not fully utilize VAS' sensitivity to important subsynoptic thermal features. Therefore, the 6 March 1982 case was reprocessed adding two enhancements to the VAS regression retrieval algorithm: (1) the regression matrix was determined using AVE profile data obtained in the region at asynoptic times, and (2) more optimistic signal-to-noise statistical conditioning factors were applied to the VAS temperature sounding channels. The new VAS soundings resolve more of the low level temperature inversion and mid-level cold pool. Most of the improvements stems from the utilization of asynoptic radiosonde observations at NWS sites. This case suggests that VAS regression soundings may require a ground-based asynoptic profiler network to bridge the gap between the synoptic radiosonde network and the high resolution geosynchronous satellite observations during the day.

Development and content validity of a screening instrument for gaming addiction in adolescents: the Gaming Addiction Identification Test (GAIT).

PubMed

Vadlin, Sofia; Åslund, Cecilia; Nilsson, Kent W

2015-08-01

This study describes the development of a screening tool for gaming addiction in adolescents - the Gaming Addiction Identification Test (GAIT). Its development was based on the research literature on gaming and addiction. An expert panel comprising professional raters (n = 7), experiential adolescent raters (n = 10), and parent raters (n = 10) estimated the content validity of each item (I-CVI) as well as of the whole scale (S-CVI/Ave), and participated in a cognitive interview about the GAIT scale. The mean scores for both I-CVI and S-CVI/Ave ranged between 0.97 and 0.99 compared with the lowest recommended I-CVI value of 0.78 and the S-CVI/Ave value of 0.90. There were no sex differences and no differences between expert groups regarding ratings in content validity. No differences in the overall evaluation of the scale emerged in the cognitive interviews. Our conclusions were that GAIT showed good content validity in capturing gaming addiction. The GAIT needs further investigation into its psychometric properties of construct validity (convergent and divergent validity) and criterion-related validity, as well as its reliability in both clinical settings and in community settings with adolescents. © 2015 Scandinavian Psychological Associations and John Wiley & Sons Ltd.

Association between adherence measurements of metoprolol and health care utilization in older patients with heart failure

PubMed Central

Tu, Wanzhu; Morris, Andrew B.; Li, Jingjin; Wu, Jingwei; Young, James; Brater, D. Craig; Murray, Michael D.

2008-01-01

Objective Data from electronic dosing monitors and published pharmacokinetic parameters were used to derive medication adherence measures for immediate-release metoprolol and examine their association with health care utilization of outpatients aged 50 years or older with heart failure. Methods We used a 1-compartment model and published population pharmacokinetic parameters to estimate mean plasma metoprolol concentrations for patients treated for 6 to 12 months. In the absence of directly measured plasma concentrations, we calculated the intended mean plasma concentration (Cp′ave) under the assumption of perfect adherence to the prescribed dose and frequency of administration. Projected mean plasma concentrations (Cpave) were estimated by use of data from recorded dosing times. In addition to taking adherence (percentage of dose taken) and scheduling adherence (percentage of doses taken on schedule), we calculated the deviation from the intended exposure (ΔCpave = Cp′ave − Cpave) and the proportion of intended exposure achieved by the patient (Cpave/Cp′ave). We assessed the association between the adherence measures and the numbers of emergency department visits and hospital admissions experienced by the patients. Results Patients (N = 80) were aged 62 ± 8 years. Mean ΔCpave and Cpave/Cp′ave were 7.9 ng/mL (SD, 10.7) and 0.6 (SD, 0.3), respectively. Log-linear models adjusted for patient functional status indicated that greater deviation from the intended metoprolol exposure (ΔCpave) was associated with increased numbers of emergency department visits (P < .0001) and hospital admissions (P < .0001). A higher proportion of intended exposure (Cpave/Cp′ave) corresponded to a reduced number of emergency department visits (P = .0204) and hospital admissions (P = .0093). Taking adherence was univariately associated with both emergency department visits and hospital visits (P < .0001 and P = .0010, respectively). Scheduling adherence was associated with

49 CFR 397.103 - Requirements for State routing designations.

Code of Federal Regulations, 2010 CFR

2010-10-01

... REGULATIONS TRANSPORTATION OF HAZARDOUS MATERIALS; DRIVING AND PARKING RULES Routing of Class 7 (Radioactive...), 1200 New Jersey Ave., SE., Washington, DC 20590-0001. Attention: National Hazardous Materials Route...

49 CFR 397.103 - Requirements for State routing designations.

Code of Federal Regulations, 2011 CFR

2011-10-01

... REGULATIONS TRANSPORTATION OF HAZARDOUS MATERIALS; DRIVING AND PARKING RULES Routing of Class 7 (Radioactive...), 1200 New Jersey Ave., SE., Washington, DC 20590-0001. Attention: National Hazardous Materials Route...

24 DOF EMG controlled hybrid actuated prosthetic hand.

PubMed

Atasoy, A; Kaya, E; Toptas, E; Kuchimov, S; Kaplanoglu, E; Ozkan, M

2016-08-01

A complete mechanical design concept of an electromyogram (EMG) controlled hybrid prosthetic hand, with 24 degree of freedom (DOF) anthropomorphic structure is presented. Brushless DC motors along with Shape Memory Alloy (SMA) actuators are used to achieve dexterous functionality. An 8 channel EMG is used for detecting 7 basic hand gestures for control purposes. The prosthetic hand will be integrated with the Neural Network (NNE) based controller in the next phase of the study.

76 FR 51120 - Notice of Opportunity for Public Comment on Release of Federally Obligated Property at Hartsfield...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-17

... Airports District Office, Attn: Aimee A. McCormick, Program Manager, 1701 Columbia Ave., Campus Building..., GA 30320-2509. FOR FURTHER INFORMATION CONTACT: Aimee McCormick, Program Manager, Atlanta Airports...

36 CFR 200.2 - Field organization.

Code of Federal Regulations, 2011 CFR

2011-07-01

...): Colorado Arapaho-Roosevelt Fort Collins. Grand Mesa-Uncompahgre and Gunnison Delta. Pike-San Isabel Pueblo... Cody. Region 3, Southwestern Region (Regional Forester, Federal Bldg., 517 Gold Ave. SW., Albuquerque...

36 CFR 200.2 - Field organization.

Code of Federal Regulations, 2014 CFR

2014-07-01

...): Colorado Arapaho-Roosevelt Fort Collins. Grand Mesa-Uncompahgre and Gunnison Delta. Pike-San Isabel Pueblo... Cody. Region 3, Southwestern Region (Regional Forester, Federal Bldg., 517 Gold Ave. SW., Albuquerque...

36 CFR 200.2 - Field organization.

Code of Federal Regulations, 2013 CFR

2013-07-01

...): Colorado Arapaho-Roosevelt Fort Collins. Grand Mesa-Uncompahgre and Gunnison Delta. Pike-San Isabel Pueblo... Cody. Region 3, Southwestern Region (Regional Forester, Federal Bldg., 517 Gold Ave. SW., Albuquerque...

36 CFR 200.2 - Field organization.

Code of Federal Regulations, 2012 CFR

2012-07-01

...): Colorado Arapaho-Roosevelt Fort Collins. Grand Mesa-Uncompahgre and Gunnison Delta. Pike-San Isabel Pueblo... Cody. Region 3, Southwestern Region (Regional Forester, Federal Bldg., 517 Gold Ave. SW., Albuquerque...

77 FR 4799 - State Energy Advisory Board (STEAB)

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-31

... Technical Advisor, U.S. Department of Energy, Office of Energy Efficiency and Renewable Energy, 1000 Independence Ave. SW., Washington, DC 20585. Phone number is (202) 287- 1644. SUPPLEMENTARY INFORMATION...

77 FR 74511 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-14

... be submitted by December 31, 2012. Before including your address, phone number, email address, or... Fort Ave., B & O RR., Woodall & Reynolds Sts., Baltimore (Independent City), 12001084 Washington County...

10 CFR 1015.101 - Prescription of standards.

Code of Federal Regulations, 2010 CFR

2010-01-01

... (DOE) Office of Financial Policy, 1000 Independence Ave., SW., Washington, DC 20585. (b) Additional... separate regulations issued by Treasury. Rules governing the use of certain debt collection tools created...

75 FR 76961 - Procurement List; Proposed Additions and Deletions

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-10

..., DC. Service Type/Location: Custodial Service. Mauna Loa Observatory: Hilo Office, 1437 Kilauea Ave., 102, Hilo, HI. NPA: The ARC of Hilo, Hilo, HI. Contracting Activity: Department of Commerce...

78 FR 32441 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-30

..., Parsonage and Cemetery, 333-334 Park Ave., Scotch Plains, 13000386 OHIO Cuyahoga County Chagrin Falls East... Dr., Nashville, 13000399 Shelby County Rosemark Historic District, 8501-8760 Kerrville-Rosemark Rd...

76 FR 11193 - Superior Resource Advisory Committee

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2011-03-01

... Forest, RAC, 8901 Grand Ave. Place, Duluth, MN 55808. Comments may also be sent via e-mail to.... FOR FURTHER INFORMATION CONTACT: Lisa Radosevich-Craig, Partnership Coordinator & Tribal Liaison...

77 FR 55185 - Application(s) for Duty-Free Entry of Scientific Instruments

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-07

..., 100 Nicolls Rd., Stony Brook, NY 11794. Instrument: Electron Microscope. Manufacturer: JEOL Ltd... of the Dean of Science, Marshak 1320 160 Convent Ave., New York, NY 10031. Instrument: Electron...

77 FR 55185 - Application(s) for Duty-Free Entry of Scientific Instruments

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-07

..., 100 Nicolls Rd., Stony Brook, NY 11794. Instrument: Electron Microscope. Manufacturer: JEOL Ltd... of the Dean of Science, Marshak 1320, 160 Convent Ave., New York, NY 10031. Instrument: Electron...

77 FR 32021 - Significant New Use Rule on a Certain Chemical Substance; Withdrawal of Significant New Use Rule

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-31

... address: [email protected] . For general information contact: The TSCA-Hotline, ABVI-Goodwill, 422 South Clinton Ave., Rochester, NY 14620; telephone number: (202) 554-1404; email address: TSCA-Hotline...

40 CFR 35.2000 - Purpose and policy.

Code of Federal Regulations, 2011 CFR

2011-07-01

... municipalities in meeting enforceable requirements of the Clean Water Act, particularly, applicable National..., 1200 Pennsylvania Ave., NW., room 1115 ET, WH 547, Washington, DC 20460. In order to expedite...

40 CFR 35.2000 - Purpose and policy.

Code of Federal Regulations, 2010 CFR

2010-07-01

... municipalities in meeting enforceable requirements of the Clean Water Act, particularly, applicable National..., 1200 Pennsylvania Ave., NW., room 1115 ET, WH 547, Washington, DC 20460. In order to expedite...

75 FR 21652 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-26

...), 4820 Howard St, NW, Washington, DC, 10000242 Woodrow Wilson High School (Public School Buildings of..., Residence, 7901 Stanford Ave, University City, 10000246 SOUTH CAROLINA Hampton County Gravel Hill Plantation...

76 FR 81912 - Notice of Petitions by Firms for Determination of Eligibility To Apply for Trade Adjustment...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-29

... parts and components such as plugs, clips, rings, handles and small doors. Applied Engineering, Inc... Dyess Ave. Rapid 12/1/2011 The firm manufactures City, SD 57701. semiconductor devices, nanotechnology...

77 FR 35424 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-13

... 721, Bradford, 12000395 PUERTO RICO Guaynabo Municipality Oficina de Telegrafo y Telefono, 1729 Jose E... County Tunnell--West House, 39 Central Ave., Ocean View, 12000379 DISTRICT OF COLUMBIA District of...

78 FR 1209 - State Energy Advisory Board (STEAB)

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-08

..., STEAB Designated Federal Officer, U.S. Department of Energy, Office of Energy Efficiency and Renewable Energy, 1000 Independence Ave. SW., Washington, DC 20585. Phone number is (202) 287-1644. SUPPLEMENTARY...

78 FR 44943 - State Energy Advisory Board (STEAB)

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-25

...: Gil Sperling, STEAB Designated Federal Officer, U.S. Department of Energy, Office of Energy Efficiency and Renewable Energy, 1000 Independence Ave. SW., Washington, DC, 20585. Phone number is (202) 287...

78 FR 6088 - State Energy Advisory Board (STEAB)

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-29

..., STEAB Designated Federal Officer, U.S. Department of Energy, Office of Energy Efficiency and Renewable Energy, 1000 Independence Ave. SW., Washington, DC 20585. Phone number is (202) 287-1644. SUPPLEMENTARY...

40 CFR 262.87 - Reporting and recordkeeping.

Code of Federal Regulations, 2010 CFR

2010-07-01

... (CONTINUED) STANDARDS APPLICABLE TO GENERATORS OF HAZARDOUS WASTE Transfrontier Shipments of Hazardous Waste... Protection Agency, 1200 Pennsylvania Ave., NW., Washington, DC 20460, no later than March 1 of each year...

75 FR 35125 - Unblocking of Specially Designated Nationals and Blocked Persons Pursuant to the Foreign...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-21

... California CP 22000, Mexico; Calle Granito No. 2025, Seccion El Dorado, Fraccionamiento Playas de Tijuana...., Ave. Azueta 11750, Col. Libertad, Tijuana, Baja California CP 22400, Mexico; c/o Accesos Electronicos...

76 FR 76811 - Stakeholders Meeting Regarding Ready Reserve Force (RRF) Ship Manager Contract Program

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-08

... for Cost Saving Methods in Program Management, Ship Costs, Green Initiatives. Limited Scope Ship... registration is recommended. The DOT building at 1200 New Jersey Ave. SE. has security entrance requirements...

21 CFR 510.600 - Names, addresses, and drug labeler codes of sponsors of approved applications.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 049185 Watson Laboratories, Inc., 311 Bonnie Circle, Corona, CA 92880. 000402 Wayne Feed Division... Olney Ave., Cherry Hill, NJ 08034. 000402 Watson Laboratories, Inc., 311 Bonnie Circle, Corona, CA 92880...

75 FR 56107 - Product Cancellation Order for Certain Pesticide Registrations

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-15

..., human health, and agricultural advocates; the chemical industry; pesticide users; and members of the... Hide Away Circle, Cub Run, KY 42729. 70127 Novozymes Biologicals, Inc., 1150 Conn. Ave., NW., Suite...

75 FR 12121 - Extended Operations (ETOPS) of Multi-Engine Airplanes; Technical Amendment

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-15

... CONTACT: Zara Willis, Office of Rulemaking, Federal Aviation Administration, 800 Independence Ave., SW., Washington, DC 20591; telephone (202) 493-4405 facsimile (202) 267- 5075; e-mail Zara[email protected

76 FR 14372 - Glenn/Colusa County Resource Advisory Committee

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-16

... agenda items contact Eduardo Olmedo, DFO, 825 N. Humboldt Ave., Willows, CA 95988 or Laurie Pearson..., Stonyford, CA 95979. FOR FURTHER INFORMATION CONTACT: Laurie Pearson, Glenn/Colusa RAC Coordinator, USDA...

77 FR 34404 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-11

... Constitution Ave., Hartford, 12000359 Kensington Grammar School--Jean E. Hooker High School, 462 Alling St..., 12000365 St. Johns County Constitution Obelisk, Plaza de la Constitution, St. Augustine, 12000364 NEW YORK...

21 CFR 184.1259 - Cocoa butter substitute.

Code of Federal Regulations, 2011 CFR

2011-04-01

... material incorporated by reference may be obtained from the AOAC INTERNATIONAL, 481 North Frederick Ave... in accordance with good manufacturing practice. (7) Residual methanol—5 parts per million maximum. (8...

21 CFR 184.1259 - Cocoa butter substitute.

Code of Federal Regulations, 2010 CFR

2010-04-01

... material incorporated by reference may be obtained from the AOAC INTERNATIONAL, 481 North Frederick Ave... in accordance with good manufacturing practice. (7) Residual methanol—5 parts per million maximum. (8...

76 FR 14426 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-16

... County Auburn Public Library, (Auburn, CA MPS) 175 Almond St, Auburn, 11000153 OREGON Washington County... County St. Mary's Rectory, 1575 Second Ave, Cumberland, 11000152 OTHER ACTIONS: Request for REMOVAL has...

77 FR 76897 - Significant New Use Rule on Certain Chemical Substances; Removal of Significant New Use Rules

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-31

... general information contact: The TSCA-Hotline, ABVI-Goodwill, 422 South Clinton Ave. Rochester, NY 14620; telephone number: (202) 554-1404; email address: TSCA-Hotline@epa.gov . SUPPLEMENTARY INFORMATION: I. Does...

40 CFR 761.187 - Reporting importers and by persons generating PCBs in excluded manufacturing processes.

Code of Federal Regulations, 2010 CFR

2010-07-01

....3, PCB-generating manufacturing processes or importers of PCB-containing products shall be..., 1200 Pennsylvania Ave., NW., Washington, DC 20460-0001, ATTN: PCB Notification. (Sec. 6, Pub. L. 94-469...

30 CFR 756.16 - Approval of the Hopi Tribe's abandoned mine land reclamation plan.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 86039, Telephone: (520) 734-2441. (b) Office of Surface Mining Reclamation and Enforcement, Albuquerque Field Office, 505 Marquette Ave., NW., Suite 1200, Albuquerque, NM 87102, Telephone: (505) 248-5070. [61...

30 CFR 756.16 - Approval of the Hopi Tribe's abandoned mine land reclamation plan.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 86039, Telephone: (520) 734-2441. (b) Office of Surface Mining Reclamation and Enforcement, Albuquerque Field Office, 505 Marquette Ave., NW., Suite 1200, Albuquerque, NM 87102, Telephone: (505) 248-5070. [61...

30 CFR 756.16 - Approval of the Hopi Tribe's abandoned mine land reclamation plan.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 86039, Telephone: (520) 734-2441. (b) Office of Surface Mining Reclamation and Enforcement, Albuquerque Field Office, 505 Marquette Ave., NW., Suite 1200, Albuquerque, NM 87102, Telephone: (505) 248-5070. [61...

30 CFR 756.16 - Approval of the Hopi Tribe's abandoned mine land reclamation plan.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 86039, Telephone: (520) 734-2441. (b) Office of Surface Mining Reclamation and Enforcement, Albuquerque Field Office, 505 Marquette Ave., NW., Suite 1200, Albuquerque, NM 87102, Telephone: (505) 248-5070. [61...

30 CFR 756.16 - Approval of the Hopi Tribe's abandoned mine land reclamation plan.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 86039, Telephone: (520) 734-2441. (b) Office of Surface Mining Reclamation and Enforcement, Albuquerque Field Office, 505 Marquette Ave., NW., Suite 1200, Albuquerque, NM 87102, Telephone: (505) 248-5070. [61...

40 CFR 98.9 - Addresses.

Code of Federal Regulations, 2014 CFR

2014-07-01

.... Director, Climate Change Division, 1200 Pennsylvania Ave., NW., Mail Code: 6207J, Washington, DC 20460. (b) For package deliveries. Director, Climate Change Division, 1310 L St, NW., Washington, DC 20005. [74...

40 CFR 98.9 - Addresses.

Code of Federal Regulations, 2012 CFR

2012-07-01

.... Director, Climate Change Division, 1200 Pennsylvania Ave., NW., Mail Code: 6207J, Washington, DC 20460. (b) For package deliveries. Director, Climate Change Division, 1310 L St, NW., Washington, DC 20005. [74...

40 CFR 98.9 - Addresses.

Code of Federal Regulations, 2013 CFR

2013-07-01

.... Director, Climate Change Division, 1200 Pennsylvania Ave., NW., Mail Code: 6207J, Washington, DC 20460. (b) For package deliveries. Director, Climate Change Division, 1310 L St, NW., Washington, DC 20005. [74...

76 FR 21005 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-14

.... Drexel Blvd., Chicago, 11000243 Kane County Hubbard, Joel H., House, 304 N. 2nd Ave., St. Charles... W. Main St., Broadalbin, 11000252 Rensselaer County Dickinson Hill Fire Tower, Fire Tower Rd...

77 FR 75616 - Procurement List; Additions

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-21

.... 611, 1919 E Grange Ave., Milwaukee, WI NPA: Easter Seals Southeast Wisconsin, Inc., South Milwaukee... B, Bldg. 39, Wright-Patterson AFB, Dayton, OH NPA: Goodwill Easter Seals Miami Valley, Dayton, OH...

75 FR 30425 - Endangered and Threatened Species Permit Applications

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-01

..., during normal business hours at the U.S. Fish and Wildlife Service, 500 Gold Ave., SW., Room 6034... transport studies for Colorado pikeminnow (Ptychochelius lucius) and razorback sucker (Xyrauchen texanus) in...

78 FR 52171 - State Energy Advisory Board (STEAB)

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-22

...: Gil Sperling, STEAB Designated Federal Officer, U.S. Department of Energy, Office of Energy Efficiency and Renewable Energy, 1000 Independence Ave. SW., Washington, DC 20585. Phone number is (202) 287-1644...

77 FR 64495 - State Energy Advisory Board (STEAB)

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-22

... Designated Federal Officer, U.S. Department of Energy, Office of Energy Efficiency and Renewable Energy, 1000 Independence Ave. SW., Washington, DC 20585. Phone number is (202) 287-1644. SUPPLEMENTARY INFORMATION: Purpose...

77 FR 20014 - State Energy Advisory Board (STEAB)

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-03

...: Gil Sperling, STEAB Designated Federal Officer, U.S. Department of Energy, Office of Energy Efficiency and Renewable Energy, 1000 Independence Ave. SW., Washington, DC 20585. Phone number is (202) 287-1644...

21 CFR 184.1400 - Lecithin.

Code of Federal Regulations, 2013 CFR

2013-04-01

... by reference. Copies are available from the National Academy Press, 2101 Constitution Ave. NW....archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. (c) In accordance with § 184...

21 CFR 184.1205 - Calcium hydroxide.

Code of Federal Regulations, 2013 CFR

2013-04-01

... Constitution Ave. NW., Washington, DC 20418, or available for inspection at the National Archives and Records...: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. (c) In...

21 CFR 184.1272 - L-Cysteine monohydrochloride.

Code of Federal Regulations, 2013 CFR

2013-04-01

... Constitution Ave. NW., Washington, DC 20418, or may be examined at the National Archives and Records...: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. (c) The...

21 CFR 184.1317 - Garlic and its derivatives.

Code of Federal Regulations, 2012 CFR

2012-04-01

... reference. Copies may be obtained from the National Academy Press, 2101 Constitution Ave. NW., Washington.../federal_register/code_of_federal_regulations/ibr_locations.html. (c) Garlic and its derivatives are used...

21 CFR 184.1317 - Garlic and its derivatives.

Code of Federal Regulations, 2013 CFR

2013-04-01

... reference. Copies may be obtained from the National Academy Press, 2101 Constitution Ave. NW., Washington.../federal_register/code_of_federal_regulations/ibr_locations.html. (c) Garlic and its derivatives are used...

21 CFR 184.1191 - Calcium carbonate.

Code of Federal Regulations, 2012 CFR

2012-04-01

... Constitution Ave. NW., Washington, DC 20418, or available for inspection at the National Archives and Records...: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. (c) In...

21 CFR 184.1135 - Ammonium bicarbonate.

Code of Federal Regulations, 2012 CFR

2012-04-01

... by reference. Copies are available from the National Academy Press, 2101 Constitution Ave. NW....archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. (c) In accordance with § 184...

21 CFR 180.30 - Brominated vegetable oil.

Code of Federal Regulations, 2012 CFR

2012-04-01

... material incorporated by reference may be obtained from the National Academy Press, 2101 Constitution Ave...://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. (b) The additive is...

21 CFR 184.1400 - Lecithin.

Code of Federal Regulations, 2012 CFR

2012-04-01

... by reference. Copies are available from the National Academy Press, 2101 Constitution Ave. NW....archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. (c) In accordance with § 184...

21 CFR 184.1272 - L-Cysteine monohydrochloride.

Code of Federal Regulations, 2012 CFR

2012-04-01

... Constitution Ave. NW., Washington, DC 20418, or may be examined at the National Archives and Records...: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. (c) The...

21 CFR 184.1191 - Calcium carbonate.

Code of Federal Regulations, 2013 CFR

2013-04-01

... Constitution Ave. NW., Washington, DC 20418, or available for inspection at the National Archives and Records...: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. (c) In...

21 CFR 184.1205 - Calcium hydroxide.

Code of Federal Regulations, 2012 CFR

2012-04-01

... Constitution Ave. NW., Washington, DC 20418, or available for inspection at the National Archives and Records...: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. (c) In...

21 CFR 184.1370 - Inositol.

Code of Federal Regulations, 2012 CFR

2012-04-01

... by reference. Copies are available from the National Academy Press, 2101 Constitution Ave. NW....archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. (c) In accordance with § 184...

7 CFR 1724.54 - Requirements for RUS approval of plans and specifications.

Code of Federal Regulations, 2010 CFR

2010-01-01

... paragraph (e) covers all portions of a generating plant including plant buildings, the generator step-up... States Department of Agriculture, Stop 1522, 1400 Independence Ave., SW., Washington, DC 20250-1522. The...

76 FR 44044 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-22

... Historic District, Buildings fronting Rodney Sq. at 10th, 11th, Market and King Sts., Wilmington IDAHO... MONTANA Missoula County Target Range Elementary School, 4095 South Ave., W., Missoula NEBRASKA Custer...

6. Historic American Buildings Survey Arthur C. Haskell, Photographer. 1935 ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

6. Historic American Buildings Survey Arthur C. Haskell, Photographer. 1935 (b) Ext-View of remaining East Portion from Atlantic Ave. - India Wharf Stores, 306-308 Atlantic Avenue, Boston, Suffolk County, MA

78 FR 8226 - Art Advisory Panel-Notice of Availability of Report of 2012 Closed Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-05

...: Internal Revenue Service, Freedom of Information Reading Room, Room 1621, 1111 Constitution Avenue NW.../Appeals, 1111 Constitution Ave. NW., Ste. 700, Washington, DC 20224, telephone (202) 435-5739 (not a toll...

78 FR 69708 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-20

... 36 CFR part 60, written comments are being accepted concerning the significance of the nominated... Quogue Cemetery, 58 Lamb Ave., Quogue, 13000914 Warren County St. James Episcopal Church, 172 Ottawa St...

77 FR 62528 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-15

... part 60, written comments are being accepted concerning the significance of the nominated properties... MPS) 42 7th Ave. SW., Cedar Rapids, 12000890 MAINE Androscoggin County Lamb Block, 10 Depot St...

76 FR 80926 - Cortez Pumped Storage Project; Notice of Preliminary Permit Application Accepted for Filing and...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-27

..., Motions To Intervene, and Competing Applications On December 1, 2011, INCA Engineers, Inc., Washington...: Mr. Donald Thompson, INCA Engineers, Inc., 400, 112th Ave. NE., Suite 400, Bellevue, WA 98004; phone...

77 FR 16219 - Cortez Pumped Storage Project; Notice of Preliminary Permit Application Accepted for Filing and...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-20

..., Motions To Intervene, and Competing Applications On November 30, 2011, INCA Engineers, Inc., Washington...: Mr. Donald Thompson, INCA Engineers, Inc., 400 112th Ave. NE., Suite 400 Bellevue, WA 98004; phone...

Evolution of alanine:glyoxylate aminotransferase 1 peroxisomal and mitochondrial targeting. A survey of its subcellular distribution in the livers of various representatives of the classes Mammalia, Aves and Amphibia.

PubMed

Danpure, C J; Fryer, P; Jennings, P R; Allsop, J; Griffiths, S; Cunningham, A

1994-08-01

As part of a wider study on the molecular evolution of alanine:glyoxylate aminotransferase 1 (AGT1) intracellular compartmentalization, we have determined the subcellular distribution of immunoreactive AGT1, using postembedding protein A-gold immunoelectron microscopy, in the livers of various members of the classes Mammalia, Aves, and Amphibia. As far as organellar distribution is concerned, three categories could be distinguished. In members of the first category (type I), all, or nearly all, of the immunoreactive AGT1 was concentrated within the peroxisomes. In the second category (type II), AGT1 was found more evenly distributed in both peroxisomes and mitochondria. In the third category (type III), AGT1 was localized mainly within the mitochondria with much lower, but widely variable, amounts in the peroxisomes. Type I animals include the human, two great apes (gorilla, orangutan), two Old World monkeys (anubis baboon, Japanese macaque), a New World monkey (white-faced Saki monkey), a lago, morph (European rabbit), a bat (Seba's short-tailed fruit bat), two caviomorph rodents (guinea pig, orange-rumped agouti), and two Australian marsupials (koala, Bennett's wallaby). Type II animals include two New World monkeys (common marmoset, cotton-top tamarin), three prosimians (brown lemur, fat-tailed dwarf lemur, pygmy slow loris), five rodents (a hybrid crested porcupine, Colombian ground squirrel, laboratory rat, laboratory mouse, golden hamster), an American marsupial (grey short-tailed opossum), and a bird (raven). Type III animals include the large tree shrew, three insectivores (common Eurasian mole, European hedgehog, house shrew), four carnivores (domestic cat, ocelot, domestic dog, polecat ferret), and an amphibian (common frog). In addition to these categories, some animals (e.g. guinea pig, common frog) possessed significant amounts of cytosolic AGT1. Whereas the subcellular distribution of AGT1 in some orders (e.g. Insectivora and Carnivora) did not appear

75 FR 47210 - Certifications and Exemptions Under the International Regulations for Preventing Collisions at...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-05

... Ave., SE., Suite 3000, Washington Navy Yard, DC 20374-5066, telephone number: 202-685-5040... and after masthead lights; and, Rule 21(a) pertaining to the forward masthead light arc of visibility...

78 FR 19585 - Change of Address; Biologics License Applications; Technical Amendment

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-02

... Evaluation and Research, Food and Drug Administration, 10903 New Hampshire Ave., Bldg. 22, rm. 1120, Silver... and Research, Food and Drug Administration, 5901B Ammendale Rd., Beltsville, MD 20705. This action is...

75 FR 34215 - Notification of Citizens Coinage Advisory Committee June 28, 2010 Public Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-16

... Worner Center, Campus of Colorado College, 902 N. Cascade Ave., Colorado Springs, CO 80903. Subject..., Congressional Gold Medals, and national and other medals. Advises the Secretary of the Treasury with regard to...

76 FR 55622 - Glymes; Proposed Significant New Use; Extension of Comment Period

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-08

...), Office of Pollution Prevention and Toxics, Environmental Protection Agency, 1200 Pennsylvania Ave., NW... Division, Office of Pollution Prevention and Toxics. [FR Doc. 2011-22988 Filed 9-7-11; 8:45 am] BILLING...

76 FR 64102 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-17

... District, Roughly bounded by S. Philpot St., East Ave, E. Ware & Park Sts., Cedartown, 11000776 IDAHO Ada... following resource: MAINE Androscoggin County Cowan Mill Island Mill St., Lewiston, 85001656 [FR Doc. 2011...

21 CFR 173.228 - Ethyl acetate.

Code of Federal Regulations, 2012 CFR

2012-04-01

... incorporated by reference. 1 Copies may be obtained from: National Academy Press, 2101 Constitution Ave. NW.../federal_register/code_of_federal_regulations/ibr_locations.html. (b) The additive is used in accordance...

21 CFR 184.1143 - Ammonium sulfate.

Code of Federal Regulations, 2012 CFR

2012-04-01

... reference. Copies may be obtained from the National Academy Press, 2101 Constitution Ave. NW., Washington.../federal_register/code_of_federal_regulations/ibr_locations.html. (c) The ingredient is used as a dough...

21 CFR 184.1141b - Ammonium phosphate, dibasic.

Code of Federal Regulations, 2012 CFR

2012-04-01

..., 2101 Constitution Ave. NW., Washington, DC 20418, or available for inspection at the National Archives... 202-741-6030, or go to: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr...

21 CFR 184.1081 - Propionic acid.

Code of Federal Regulations, 2012 CFR

2012-04-01

..., 2101 Constitution Ave. NW., Washington, DC 20418, or available for inspection at the National Archives... 202-741-6030, or go to: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr...

21 CFR 173.228 - Ethyl acetate.

Code of Federal Regulations, 2013 CFR

2013-04-01

... incorporated by reference. 1 Copies may be obtained from: National Academy Press, 2101 Constitution Ave. NW.../federal_register/code_of_federal_regulations/ibr_locations.html. (b) The additive is used in accordance...

40 CFR 52.1675 - Control strategy and regulations: Sulfur oxides.

Code of Federal Regulations, 2010 CFR

2010-07-01

...-down; One boiler converted; South Campus—Boiler Plant: Converted; North Campus Science and Physical Education Building: October 1, 1980. (b) Harlem Hospital, 135th St. and Lenox Ave., Manhattan: April 1, 1981...

76 FR 70448 - Publication of Inaccurate or Inactive Ocean Common Carrier Tariffs; Order to Show Cause

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-14

... competing carriers, and an administrative burden upon our staff for ``paper'' tariffs to be kept on file... Shipping Corporation S.A., Torre Universal, Ave 013897 Federico Boyd, Panama City, Panama BSLE Malta...

77 FR 51041 - Approval of Inspectorate America Corporation, as a Commercial Gauger

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-23

... Paris Ave., Baton Rouge, LA 70814, has been approved to gauge petroleum, petroleum products, organic chemicals and vegetable oils for customs purposes, in accordance with the provisions of 19 CFR 151.13...

77 FR 75183 - Accreditation and Approval of Intertek USA, Inc., as a Commercial Gauger and Laboratory

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-19

... 151.13, Intertek USA, Inc., 2632 Ruby Ave., Gonzales, LA 70737, has been approved to gauge and... 20229, 202-344- 1060. Dated: December 12, 2012. Ira S. Reese, Executive Director, Laboratories and...

75 FR 43930 - Notice of Petitions by Firms for Determination of Eligibility To Apply for Trade Adjustment...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-27

.... circuit boards, which are produced using epoxy resin insulating layers and copper, and other conductive material, conducting layers. Ex-Cell Kaiser, LLC 11240 Melrose Ave., 7/13/2010 Company is a contract...

78 FR 48901 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-12

..., 13000637 NORTH DAKOTA Grand Forks County Hariman Sanatorium, 2002 University Ave., Grand Forks, 13000633... Municipal de la Playa de Ponce, 28 Alfonso XII St., Ponce, 13000639 UTAH Salt Lake County Bennion, Howard...

77 FR 45373 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-31

..., 12000527 Mercer County Roebling's, John A., Sons Company, Trenton, N.J., Block 3, Bounded by Hamilton Ave... St., Yankton, 12000536 VIRGINIA Arlington County Georgetown Pike, From DC/VA boundary at Chain Bridge...

Progress of long pulse discharges by ECH in LHD

NASA Astrophysics Data System (ADS)

Yoshimura, Y.; Kasahara, H.; Tokitani, M.; Sakamoto, R.; Ueda, Y.; Ito, S.; Okada, K.; Kubo, S.; Shimozuma, T.; Igami, H.; Takahashi, H.; Tsujimura, T. I.; Makino, R.; Kobayashi, S.; Mizuno, Y.; Akiyama, T.; Ashikawa, N.; Masuzaki, S.; Motojima, G.; Shoji, M.; Suzuki, C.; Tanaka, H.; Tanaka, K.; Tokuzawa, T.; Tsuchiya, H.; Yamada, I.; Goto, Y.; Yamada, H.; Mutoh, T.; Komori, A.; Takeiri, Y.; the LHD Experiment Group

2016-04-01

Using ion cyclotron heating and electron cyclotron heating (ECH), or solo ECH, trials of steady state plasma sustainment have been conducted in the superconducting helical/stellarator, large helical device (LHD) (Ida K et al 2015 Nucl. Fusion 55 104018). In recent years, the ECH system has been upgraded by applying newly developed 77 and 154 GHz gyrotrons. A new gas fueling system applied to the steady state operations in the LHD realized precise feedback control of the line average electron density even when the wall condition varied during long pulse discharges. Owing to these improvements in the ECH and the gas fueling systems, a stable 39 min discharge with a line average electron density n e_ave of 1.1  ×  1019 m-3, a central electron temperature T e0 of over 2.5 keV, and a central ion temperature T i0 of 1.0 keV was successfully performed with ~350 kW EC-waves. The parameters are much improved from the previous 65 min discharge with n e_ave of 0.15  ×  1019 m-3 and T e0 of 1.7 keV, and the 30 min discharge with n e_ave of 0.7  ×  1019 m-3 and T e0 of 1.7 keV.

77 FR 53231 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-31

... School, Old, 301 Harmon Ave., Fort Lauderdale, 12000790 Polk County Lewis, W. Henry, House, 424 N. Oak St., Fort Meade, 12000791 IOWA Clinton County Clinton High School and Public Library (Clinton, Iowa MPS...

77 FR 26749 - Agency Information Collection Extension

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-07

... difficulty in submitting comments within that period, contact the person listed below as soon as possible. ADDRESSES: Written comments may be sent to: Eva Auman, GC-63, Department of Energy, 1000 Independence Ave...

21 CFR 184.1141a - Ammonium phosphate, monobasic.

Code of Federal Regulations, 2012 CFR

2012-04-01

... Academy Press, 2101 Constitution Ave. NW., Washington, DC 20418, or available for inspection at the... at NARA, call 202-741-6030, or go to: http://www.archives.gov/federal_register/code_of_federal...

76 FR 20689 - Guidance for Industry on Influenza: Developing Drugs for Treatment and/or Prophylaxis; Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-13

... Hampshire Ave., Bldg. 51, rm. 2201, Silver Spring, MD 20993-0002. Send one self-addressed adhesive label to... exploration and verification of drug effects under epidemic and pandemic conditions. A draft notice of...

78 FR 44149 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-23

... guarantee that we will be able to do so. Dated: July 5, 2013. J. Paul Loether, Chief, National Register of..., 13000591 COLORADO Logan County Downtown Sterling Historic District, Roughly bounded by Division Ave...

21 CFR 510.600 - Names, addresses, and drug labeler codes of sponsors of approved applications.

Code of Federal Regulations, 2010 CFR

2010-04-01

... Laboratories, Inc., 311 Bonnie Circle, Corona, CA 92880. 000402 Wayne Feed Division, Continental Grain Co., P.O..., 24 Olney Ave., Cherry Hill, NJ 08034. 000402 Watson Laboratories, Inc., 311 Bonnie Circle, Corona, CA...

21 CFR 314.445 - Guidance documents.

Code of Federal Regulations, 2014 CFR

2014-04-01

... Evaluation and Research, Food and Drug Administration, 10903 New Hampshire Ave., Silver Spring, MD 20993-0002... HUMAN USE APPLICATIONS FOR FDA APPROVAL TO MARKET A NEW DRUG Miscellaneous Provisions § 314.445 Guidance...

21 CFR 314.445 - Guidance documents.

Code of Federal Regulations, 2012 CFR

2012-04-01

... Evaluation and Research, Food and Drug Administration, 10903 New Hampshire Ave., Silver Spring, MD 20993-0002... HUMAN USE APPLICATIONS FOR FDA APPROVAL TO MARKET A NEW DRUG Miscellaneous Provisions § 314.445 Guidance...

21 CFR 314.445 - Guidance documents.

Code of Federal Regulations, 2011 CFR

2011-04-01

... Evaluation and Research, Food and Drug Administration, 10903 New Hampshire Ave., Silver Spring, MD 20993-0002... HUMAN USE APPLICATIONS FOR FDA APPROVAL TO MARKET A NEW DRUG Miscellaneous Provisions § 314.445 Guidance...

21 CFR 314.445 - Guidance documents.

Code of Federal Regulations, 2013 CFR

2013-04-01

... Evaluation and Research, Food and Drug Administration, 10903 New Hampshire Ave., Silver Spring, MD 20993-0002... HUMAN USE APPLICATIONS FOR FDA APPROVAL TO MARKET A NEW DRUG Miscellaneous Provisions § 314.445 Guidance...

75 FR 40827 - Proposed Consent Decree, Clean Air Act Citizen Suit

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-14

... Foam Production (40 CFR part 63, subpart III); (22) Acrylic and Modacrylic Fibers Production (40 CFR..., 1301 Constitution Ave., NW., Washington, DC. The EPA Docket Center Public Reading Room is open from 8...

76 FR 47211 - Report on the Performance of Drug and Biologics Firms in Conducting Postmarketing Requirements...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-04

.... This notice is the Agency's report on the status of the studies and clinical trials that applicants..., Center for Drug Evaluation and Research, Food and Drug Administration, 10903 New Hampshire Ave., Bldg. 22...

78 FR 61381 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-03

... Armory, 522 N. Howard Ave., Tampa, 13000852 Lee County Captiva School and Chapel-by-the-Sea Historic... (Independent City), 13000858 OREGON Deschutes County Petersen Rock Garden, 7930 SW. 77th St., Redmond, 13000859...

21 CFR 807.37 - Inspection of establishment registration and device listings.

Code of Federal Regulations, 2011 CFR

2011-04-01

... Hampshire Ave., Bldg. 66, rm. 3521, Silver Spring, MD 20993-0002. In addition, there will be available for.... 66, rm. 3521, Silver Spring, MD 20993-0002. (3) Requests for device listing information not...

30 CFR 756.13 - Approval of the Navajo Nation's abandoned mine land plan.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Mining Reclamation and Enforcement, Albuquerque Field Office, 505 Marquette Ave., NW., Suite 1200, Albuquerque, NM 87102, Telephone: (505) 248-5070. [60 FR 33724, June 29, 1995, as amended at 61 FR 6508, Feb...

30 CFR 756.13 - Approval of the Navajo Nation's abandoned mine land plan.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Mining Reclamation and Enforcement, Albuquerque Field Office, 505 Marquette Ave., NW., Suite 1200, Albuquerque, NM 87102, Telephone: (505) 248-5070. [60 FR 33724, June 29, 1995, as amended at 61 FR 6508, Feb...

30 CFR 756.13 - Approval of the Navajo Nation's abandoned mine land plan.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Mining Reclamation and Enforcement, Albuquerque Field Office, 505 Marquette Ave., NW., Suite 1200, Albuquerque, NM 87102, Telephone: (505) 248-5070. [60 FR 33724, June 29, 1995, as amended at 61 FR 6508, Feb...

30 CFR 756.13 - Approval of the Navajo Nation's abandoned mine land plan.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Mining Reclamation and Enforcement, Albuquerque Field Office, 505 Marquette Ave., NW., Suite 1200, Albuquerque, NM 87102, Telephone: (505) 248-5070. [60 FR 33724, June 29, 1995, as amended at 61 FR 6508, Feb...

30 CFR 756.13 - Approval of the Navajo Nation's abandoned mine land plan.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Mining Reclamation and Enforcement, Albuquerque Field Office, 505 Marquette Ave., NW., Suite 1200, Albuquerque, NM 87102, Telephone: (505) 248-5070. [60 FR 33724, June 29, 1995, as amended at 61 FR 6508, Feb...

77 FR 31376 - Federal Property Suitable as Facilities to Assist the Homeless

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-25

..., Arlington, VA 22202; GSA: Mr. John E.B. Smith, General Services Administration, Office of Real Property..., 1330 Patterson Ave. SW., Suite 1000, Washington, DC 20374; (202) 685-9426, (202) 501-0084; (These are...

Phenotypic and genetic relationships of feeding behavior with feed intake, growth performance, feed efficiency, and carcass merit traits in Angus and Charolais steers.

PubMed

Chen, L; Mao, F; Crews, D H; Vinsky, M; Li, C

2014-03-01

Feeding behavior traits including daily feeding duration (FD), daily feeding head down time (HD), average feeding duration per feeding event (FD_AVE), average feeding head down time per feeding event (HD_AVE), feeding frequency (FF), and meal eating rate (ER) were analyzed to estimate their phenotypic and genetic correlations with feed intake, growth performance, residual feed intake (RFI), ultrasound, and carcass merit traits in Angus and Charolais finishing steers. Heritability estimates for FD, HD, FD_AVE, HD_AVE, FF, and ER were 0.27 ± 0.09 (SE), 0.25 ± 0.09, 0.19 ± 0.06, 0.11 ± 0.05, 0.24 ± 0.08, and 0.38 ± 0.10, respectively, in the Angus population and 0.49 ± 0.12, 0.38 ± 0.11, 0.31 ± 0.09, 0.29 ± 0.10, 0.43 ± 0.11, and 0.56 ± 0.13, respectively, in the Charolais population. In both the Angus and Charolais steer populations, FD and HD had relatively stronger phenotypic (0.17 ± 0.06 to 0.32 ± 0.04) and genetic (0.29 ± 0.17 to 0.54 ± 0.18) correlations with RFI in comparison to other feeding behavior traits investigated, suggesting the potential of FD and HD as indicators in assessing variation of RFI. In general, feeding behavior traits had weak phenotypic correlations with most of the ultrasound and carcass merit traits; however, estimated genetic correlations of the feeding behavior traits with some fat deposition related traits were moderate to moderately strong but differed in magnitude or sign between the Angus and Charolais steer populations, likely reflecting their different biological types. Genetic parameter estimation studies involving feeding behavior traits in beef cattle are lacking and more research is needed to better characterize the relationships between feeding behavior and feed intake, growth, feed utilization, and carcass merit traits, in particular with respect to different biological types of cattle.

Exploring the effect of previous inactivated influenza vaccination on seasonal influenza vaccine effectiveness against medically attended influenza: Results of the European I-MOVE multicentre test-negative case-control study, 2011/2012-2016/2017.

PubMed

Valenciano, Marta; Kissling, Esther; Larrauri, Amparo; Nunes, Baltazar; Pitigoi, Daniela; O'Donnell, Joan; Reuss, Annicka; Horváth, Judit Krisztina; Paradowska-Stankiewicz, Iwona; Rizzo, Caterina; Falchi, Alessandra; Daviaud, Isabelle; Brytting, Mia; Meijer, Adam; Kaic, Bernard; Gherasim, Alin; Machado, Ausenda; Ivanciuc, Alina; Domegan, Lisa; Schweiger, Brunhilde; Ferenczi, Annamária; Korczyńska, Monika; Bella, Antonino; Vilcu, Ana-Maria; Mosnier, Anne; Zakikhany, Katherina; de Lange, Marit; Kurečić Filipovićović, Sanja; Johansen, Kari; Moren, Alain

2018-04-16

Results of previous influenza vaccination effects on current season influenza vaccine effectiveness (VE) are inconsistent. To explore previous influenza vaccination effects on current season VE among population targeted for vaccination. We used 2011/2012 to 2016/2017 I-MOVE primary care multicentre test-negative data. For each season, we compared current season adjusted VE (aVE) between individuals vaccinated and unvaccinated in previous season. Using unvaccinated in both seasons as a reference, we then compared aVE between vaccinated in both seasons, current only, and previous only. We included 941, 2645 and 959 influenza-like illness patients positive for influenza A(H1N1)pdm09, A(H3N2) and B, respectively, and 5532 controls. In 2011/2012, 2014/2015 and 2016/2017, A(H3N2) aVE point estimates among those vaccinated in previous season were -68%, -21% and -19%, respectively; among unvaccinated in previous season, these were 33%, 48% and 46%, respectively (aVE not computable for influenza A(H1N1)pdm09 and B). Compared to current season vaccination only, VE for both seasons' vaccination was (i) similar in two of four seasons for A(H3N2) (absolute difference [ad] 6% and 8%); (ii) lower in three of four seasons for influenza A(H1N1)pdm09 (ad 18%, 26% and 29%), in two seasons for influenza A(H3N2) (ad 27% and 39%) and in two of three seasons for influenza B (ad 26% and 37%); (iii) higher in one season for influenza A(H1N1)pdm09 (ad 20%) and influenza B (ad 24%). We did not identify any pattern of previous influenza vaccination effect. Prospective cohort studies documenting influenza infections, vaccinations and vaccine types are needed to understand previous influenza vaccinations' effects. © 2018 The Authors. Influenza and Other Respiratory Viruses Published by John Wiley & Sons Ltd.

Use of IPA to demonstrate loss of forest interior birds from isolated woodlots

USGS Publications Warehouse

Robbins, C.S.; Boone, D.D.; Purroy, F.J.

1983-01-01

'Empleo de indices puntuales de abundancia (IPA) para demostrar la perdida de aves forestales en bosques aislados'. En Maryland, E.U., se seleccionaron bloques boscosos de diferente superficie, divididos en seis clase de tamano (2,8-6 ha, 7-14, 20-30, 34-80, 105-1300, mayores de 4000 ha). En estas ?islas' forestales fue programado un conjunto de muestreos puntuales con estas caracteristicas: 1) Cada punto se visito tres veces. 2) En cada visita se hicieron cuatro censos consecutivos de 5 minutos de duracion, empleando diferentes simbolos para machos cantores, adultos no cantores, aves en vuelo y aves inmaduras. 3) Los conteos se hicieron en tres epocas: final de Mayo, mitad de Junio y final de Junio. 4) Se dividio el tiempo de censo en tres priodos horarios: 5,15-6,30 ; 6,30-8; 8-9,30 hrs. 5) Los puntos se agruparon en co juntos de 4 a 9, considerando que un conjunto es el nlimero que un observador puede cubrir por manana. 6) La vegetacion fue descrita exhaustivamente en cuanto composicion y fisionomla. El principal objetivo que se busca consiste en conocer los requisitos areales de ciertas especies de bosque muy sensibles a la fragmentacion del habitat. Puede observarse (Figura 1) que una serie de migrantes de largo alcance se asientan en relacion con el aumento de la superficie del rodal arbo1ado, sabre todo en macizos de 4.000 o mas hectareas. Sin embargo, las especies sedentarias (Fig. 2) tienen pauta de presencia irregular en funcion del area, forestal, con tendencia a presentarse menos en los bosques mas extensos, Dryocopus pileatus, por excepcion, reacciona negativamente al pequeno tamano de la parcela arbolado, prefiriendo bosques grandes. Parecida respuesta da tambien Sitta carolinensis. Aunque se sabe poco de las exigencias areales de las aves forestales americanas, el metodo de los IPA resulta muy adecuado para esta clase de investigacion de tanto interes en gestion ambiental, posibilitando colectar gran cantidad de datos comparables en un periodo de

FORMULATION OF NON-STEADY-STATE DUST FORMATION PROCESS IN ASTROPHYSICAL ENVIRONMENTS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nozawa, Takaya; Kozasa, Takashi, E-mail: takaya.nozawa@ipmu.jp

2013-10-10

The non-steady-state formation of small clusters and the growth of grains accompanied by chemical reactions are formulated under the consideration that the collision of key gas species (key molecule) controls the kinetics of dust formation process. The formula allows us to evaluate the size distribution and condensation efficiency of dust formed in astrophysical environments. We apply the formulation to the formation of C and MgSiO{sub 3} grains in the ejecta of supernovae, as an example, to investigate how the non-steady effect influences the formation process, condensation efficiency f{sub con,{sub ∞}}, and average radius a{sub ave,{sub ∞}} of newly formed grainsmore » in comparison with the results calculated with the steady-state nucleation rate. We show that the steady-state nucleation rate is a good approximation if the collision timescale of key molecule τ{sub coll} is much smaller than the timescale τ{sub sat} with which the supersaturation ratio increases; otherwise the effect of the non-steady state becomes remarkable, leading to a lower f{sub con,{sub ∞}} and a larger a{sub ave,{sub ∞}}. Examining the results of calculations, we reveal that the steady-state nucleation rate is applicable if the cooling gas satisfies Λ ≡ τ{sub sat}/τ{sub coll} ∼> 30 during the formation of dust, and find that f{sub con,{sub ∞}} and a{sub ave,{sub ∞}} are uniquely determined by Λ{sub on} at the onset time t{sub on} of dust formation. The approximation formulae for f{sub con,{sub ∞}} and a{sub ave,{sub ∞}} as a function of Λ{sub on} could be useful in estimating the mass and typical size of newly formed grains from observed or model-predicted physical properties not only in supernova ejecta but also in mass-loss winds from evolved stars.« less

21 CFR 184.1490 - Methylparaben.

Code of Federal Regulations, 2013 CFR

2013-04-01

... National Academy Press, 2101 Constitution Ave. NW., Washington, DC 20418, or may be examined at the... at NARA, call 202-741-6030, or go to: http://www.archives.gov/federal_register/code_of_federal...

21 CFR 184.1670 - Propylparaben.

Code of Federal Regulations, 2012 CFR

2012-04-01

... National Academy Press, 2101 Constitution Ave. NW., Washington, DC 20418, or may be examined at the... at NARA, call 202-741-6030, or go to: http://www.archives.gov/federal_register/code_of_federal...

21 CFR 184.1670 - Propylparaben.

Code of Federal Regulations, 2013 CFR

2013-04-01

... National Academy Press, 2101 Constitution Ave. NW., Washington, DC 20418, or may be examined at the... at NARA, call 202-741-6030, or go to: http://www.archives.gov/federal_register/code_of_federal...

21 CFR 184.1490 - Methylparaben.

Code of Federal Regulations, 2012 CFR

2012-04-01

... National Academy Press, 2101 Constitution Ave. NW., Washington, DC 20418, or may be examined at the... at NARA, call 202-741-6030, or go to: http://www.archives.gov/federal_register/code_of_federal...

21 CFR 184.1091 - Succinic acid.

Code of Federal Regulations, 2012 CFR

2012-04-01

... National Academy Press, 2101 Constitution Ave. NW., Washington, DC 20418, or may be examined at the... at NARA, call 202-741-6030, or go to: http://www.archives.gov/federal_register/code_of_federal...

21 CFR 184.1409 - Ground limestone.

Code of Federal Regulations, 2012 CFR

2012-04-01

... National Academy Press, 2101 Constitution Ave. NW., Washington, DC 20418, or available for inspection at... material at NARA, call 202-741-6030, or go to: http://www.archives.gov/federal_register/code_of_federal...

21 CFR 184.1293 - Ethyl alcohol.

Code of Federal Regulations, 2012 CFR

2012-04-01

... available from the National Academy Press, Box 285, 2101 Constitution Ave. NW., Washington, DC 20055... material at NARA, call 202-741-6030, or go to: http://www.archives.gov/federal_register/code_of_federal...

21 CFR 184.1409 - Ground limestone.

Code of Federal Regulations, 2013 CFR

2013-04-01

... National Academy Press, 2101 Constitution Ave. NW., Washington, DC 20418, or available for inspection at... material at NARA, call 202-741-6030, or go to: http://www.archives.gov/federal_register/code_of_federal...

75 FR 10814 - National Register of Historic Places; Weekly Listing of Historic Properties

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-09

..., LISTED, 12/18/09 (Newton MRA) Plymouth County Marshfield Hills HD, Bow, Highland, Main, Old Main... MINNESOTA Blue Earth County Mapleton Public Library, 104 1st. Ave. NE, Mapleton, 09001097, LISTED, 12/18/09...

Early Restoration Public Meeting, Washington, DC | NOAA Gulf Spill

Science.gov Websites

benefit injured marshes, coastal dune and nearshore habitats, oysters, and human uses (on water recreation . Department of Commerce Herbert Hoover Building Auditorium 1401 Constitution Ave., NW Washington, D.C. 20230

76 FR 26247 - Environmental Technologies Trade Advisory Committee Public Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-06

... DEPARTMENT OF COMMERCE International Trade Administration Environmental Technologies Trade... meeting of the Environmental Technologies Trade Advisory Committee (ETTAC). DATES: The meeting is... & Environmental Industries (OEEI), International Trade Administration, Room 4053, 1401 Constitution Ave, NW...

5. Historic American Buildings Survey Frank O. Branzetti, Photographer July ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

5. Historic American Buildings Survey Frank O. Branzetti, Photographer July 16, 1940 (k) 8- MILE STONE, 741 CANTON AVE., MILTON - Milestones C, F, G, K, FFF & JJJ, Various Milton locations, Milton, Norfolk County, MA

Find a Physical Medicine & Rehabilitation Physician

MedlinePlus

... password Create a new account American Academy of Physical Medicine and Rehabilitation 9700 W. Bryn Mawr Ave ... Physiatry About Physiatry History of the Specialty About Physical Medicine and Rehabilitation Find a PM&R Physician ...

76 FR 73758 - Additional Designation of Four Entities Pursuant to Executive Order 13382

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-29

...., Karegar e Shomali, Tehran; Persian Gulf Boulevard, Km20 SW Esfahan Road, Iran) NOOR AFZAR GOSTAR COMPANY... Gharb), Darya Ave, 19697 Tehran, Iran) YASA PART (a.k.a.: Arfa Paint Company, Arfeh Company, Farasepehr...

78 FR 32682 - Federal Property Suitable as Facilities To Assist the Homeless

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-31

..., 1800 F Street NW., Room 7040, Washington, DC 20405, (202) 501-0084; NASA: Mr. Frank T. Bellinger... more details Iowa NRCS-USDA Unit 1820 E. Euclid Ave. Des Moines IA 50313 Landholding Agency: GSA...

75 FR 7233 - North Pacific Fishery Management Council; Public Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-18

... North Pacific Fishery Management Council's (Council) Scallop Plan Team will meet March 3 and 4th, 2010... Point Lena Road, Juneau, AK. Council address: North Pacific Fishery Management Council, 605 W. 4th Ave...

Grief and Loss as Alzheimer's Progresses

MedlinePlus

... for Care Costs Paying for Care Insurance Social Security Disability Medicare Medicare Part D Benefits Medicaid Tax ... Ave. Floor 17 Chicago, IL 60601 Contact Us Security and Privacy Policy Copyrights and Reprints Pressroom Select ...

Types of Dementia

MedlinePlus

... for Care Costs Paying for Care Insurance Social Security Disability Medicare Medicare Part D Benefits Medicaid Tax ... Ave. Floor 17 Chicago, IL 60601 Contact Us Security and Privacy Policy Copyrights and Reprints Pressroom Select ...

Caregiver Depression

MedlinePlus

... for Care Costs Paying for Care Insurance Social Security Disability Medicare Medicare Part D Benefits Medicaid Tax ... Ave. Floor 17 Chicago, IL 60601 Contact Us Security and Privacy Policy Copyrights and Reprints Pressroom Select ...

Abuse

MedlinePlus

... for Care Costs Paying for Care Insurance Social Security Disability Medicare Medicare Part D Benefits Medicaid Tax ... Ave. Floor 17 Chicago, IL 60601 Contact Us Security and Privacy Policy Copyrights and Reprints Pressroom Select ...

Tips for Daily Life

MedlinePlus

... for Care Costs Paying for Care Insurance Social Security Disability Medicare Medicare Part D Benefits Medicaid Tax ... Ave. Floor 17 Chicago, IL 60601 Contact Us Security and Privacy Policy Copyrights and Reprints Pressroom Select ...

Food, Eating and Alzheimer's

MedlinePlus

... for Care Costs Paying for Care Insurance Social Security Disability Medicare Medicare Part D Benefits Medicaid Tax ... Ave. Floor 17 Chicago, IL 60601 Contact Us Security and Privacy Policy Copyrights and Reprints Pressroom Select ...

Communication and Alzheimer's

MedlinePlus

... for Care Costs Paying for Care Insurance Social Security Disability Medicare Medicare Part D Benefits Medicaid Tax ... Ave. Floor 17 Chicago, IL 60601 Contact Us Security and Privacy Policy Copyrights and Reprints Pressroom Select ...

78 FR 95 - Notice of Receipt of Requests for Amendments To Delete Uses in Certain Pesticide Registrations

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-02

....S.A. Corporation, 1600 Riviera Ave., Suite 200, Walnut Creek, CA 94596. 66330 Arysta LifeScience..., FL 33881-9432. 85904 Arysta LifeScience America, Inc., 1450 Broadway, 7th Floor, New York, NY 10018...

Coastal upwelling by wind-driven forcing in Jervis Bay, New South Wales: A numerical study for 2011

NASA Astrophysics Data System (ADS)

Sun, Youn-Jong; Jalón-Rojas, Isabel; Wang, Xiao Hua; Jiang, Donghui

2018-06-01

The Princeton Ocean Model (POM) was used to investigate an upwelling event in Jervis Bay, New South Wales (SE Australia), with varying wind directions and strengths. The POM was adopted with a downscaling approach for the regional ocean model one-way nested to a global ocean model. The upwelling event was detected from the observed wind data and satellite sea surface temperature images. The validated model reproduced the upwelling event showing the input of bottom cold water driven by wind to the bay, its subsequent deflection to the south, and its outcropping to the surface along the west and south coasts. Nevertheless, the behavior of the bottom water that intruded into the bay varied with different wind directions and strengths. Upwelling-favorable wind directions for flushing efficiency within the bay were ranked in the following order: N (0°; northerly) > NNE (30°; northeasterly) > NW (315°; northwesterly) > NE (45°; northeasterly) > ENE (60°; northeasterly). Increasing wind strengths also enhance cold water penetration and water exchange. It was determined that wind-driven downwelling within the bay, which occurred with NNE, NE and ENE winds, played a key role in blocking the intrusion of the cold water upwelled through the bay entrance. A northerly wind stress higher than 0.3 N m-2 was required for the cold water to reach the northern innermost bay.

Bus current analysis of high power cryocooler's controller

NASA Astrophysics Data System (ADS)

Jin, Zhanlei; Sun, Qiyang; Dai, Liqun; Dong, Jie

2016-03-01

Current analysis was an important research content for reducing power of cryocooler's controller. Simulation was done among load current, H bridge current and power current refer to 42V bus power voltage. Then relationship among IL1, IC1, ρ and IM1 was established. Simulation results indicate that IL1-max, IL1-ave, IL1-rms, IC1-min and IC1-ave were linearly increasing to ρ and IM1, especially IL1-rms ≈ 0.612ρ IM1-max . IC1-rms increase firstly then decrease with the increasing of ρ. IC1-rms reaches maximum when ρ=0.8, then ICL-rms =(12.32/RM1 + 0.98) exp -((ρ-0.78)/0.57)2. The results were useful for miniaturizing cryocooler's controller.

A new troodontid dinosaur from China with avian-like sleeping posture.

PubMed

Xu, Xing; Norell, Mark A

2004-10-14

Discovering evidence of behaviour in fossilized vertebrates is rare. Even rarer is evidence of behaviour in non-avialan dinosaurs that directly relates to stereotypical behaviour seen in extant birds (avians) and not previously predicted in non-avialan dinosaurs. Here we report the discovery of a new troodontid taxon from the Early Cretaceous Yixian Formation of western Liaoning, China. Numerous other three-dimensionally preserved vertebrate fossils have been recovered recently at this locality, including some specimens preserving behavioural information. The new troodontid preserves several features that have been implicated in avialan origins. Notably, the specimen is preserved in the stereotypical sleeping or resting posture found in extant Aves. Evidence of this behaviour outside of the crown group Aves further demonstrates that many bird features occurred early in dinosaurian evolution.

21 CFR 184.1257 - Clove and its derivatives.

Code of Federal Regulations, 2010 CFR

2010-04-01

..., 2101 Constitution Ave. NW., Washington, DC 20055 (Internet address http://www.nap.edu), or may be... oil between 1.036 and 1.060; and (5) Residual solvent free, except those solvents that are GRAS or...

21 CFR 184.1257 - Clove and its derivatives.

Code of Federal Regulations, 2011 CFR

2011-04-01

..., 2101 Constitution Ave. NW., Washington, DC 20055 (Internet address http://www.nap.edu), or may be... oil between 1.036 and 1.060; and (5) Residual solvent free, except those solvents that are GRAS or...

21 CFR 184.1257 - Clove and its derivatives.

Code of Federal Regulations, 2013 CFR

2013-04-01

..., 2101 Constitution Ave. NW., Washington, DC 20055 (Internet address http://www.nap.edu), or may be... oil between 1.036 and 1.060; and (5) Residual solvent free, except those solvents that are GRAS or...

21 CFR 184.1257 - Clove and its derivatives.

Code of Federal Regulations, 2012 CFR

2012-04-01

..., 2101 Constitution Ave. NW., Washington, DC 20055 (Internet address http://www.nap.edu), or may be... oil between 1.036 and 1.060; and (5) Residual solvent free, except those solvents that are GRAS or...

76 FR 77249 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-12

...), (Asheville Historic and Architectural MRA) 76- 129 Biltmore Ave., 64 Carter St., 11-23 Grove St., 14-44 N..., (Chatham County MRA) 2488 Wade Paschal Rd., Siler City, 11000973 Henderson County Rice, Clough H., House...

Foundation for Sarcoidosis Research

MedlinePlus

... a Clinical Trial Our mission is to stop sarcoidosis — join us. The sarcoidosis community needs your help ... receive periodic emails from the Foundation. Foundation For Sarcoidosis Research 1820 W. Webster Ave., Ste 304 Chicago, ...

76 FR 15992 - Endangered and Threatened Species Permit Applications

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-22

..., during normal business hours at the U.S. Fish and Wildlife Service, 500 Gold Ave. SW., Room 6034... Colorado. Permit TE-33921A Applicant: City of San Antonio, San Antonio, Texas. Applicant requests a new...

77 FR 31610 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-29

... online viewing at http://www.regulations.gov , or in person viewing at the Air and Radiation Docket, in the EPA Docket Center (EPA/DC), EPA West, Room 3334, 1301 Constitution Ave. NW., Washington, DC. Joe...

77 FR 49450 - Issues in the Design of Clinical Trials of Antibacterial Drugs for the Treatment of Non-Cystic...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-16

...:30 p.m. Location: The public workshop will be held at the Sheraton Silver Spring Hotel, 8777 Georgia Ave., Silver Spring, MD 20910. The hotel's phone number is 301-589-0800. Seating is limited and...

2. Historic American Buildings Survey Frank O. Branzetti, Photographer July ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. Historic American Buildings Survey Frank O. Branzetti, Photographer July 23, 1940 (hhh) 5- MILE STONE, 879 BLUE HILL AVE., DORCHESTER - Milestones A, B, E, HHH, III & PPP, Various Dorchester locations, Dorchester, Suffolk County, MA

5. Historic American Buildings Survey Frank O. Branzetti, Photographer July ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

5. Historic American Buildings Survey Frank O. Branzetti, Photographer July 17, 1940 (ppp) 7- MILE STONE, 1411 BLUE HILL AVE., DORCHESTER - Milestones A, B, E, HHH, III & PPP, Various Dorchester locations, Dorchester, Suffolk County, MA

76 FR 81901 - Approval and Promulgation of Implementation Plans and Designations of Areas for Air Quality...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-29

....071 0.082 0.082 1009). Rowan County (NC) 301 West St & Gold Hill Ave. (37-159- 0.084 0.071 0.077 0.077... Environmental protection, Air pollution control, Incorporation by reference, Intergovernmental relations...

78 FR 17429 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-21

... review, we cannot guarantee that we will be able to do so. Dated: February 21, 2013. J. Paul Loether..., Barn, (Agriculture-Related Resources of Kansas MPS) 200th Ave. & M Rd., Penokee, 13000149 Logan County...

Medulloblastoma

MedlinePlus

... being seen. Take time to speak with your healthcare team to learn how these statistics apply to your individual situation. Click here to ... American Brain Tumor Association 8550 W. Bryn Mawr Ave. Ste 550 Chicago, ...

78 FR 42038 - Privacy Act New System of Records

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-15

... A300, Room A326, 1401 Constitution Avenue NW., Washington, DC 20230, 202-482-3258. FOR FURTHER INFORMATION CONTACT: Brenda Dolan, U.S. Department of Commerce, Suite A300, Room A326, 1401 Constitution Ave...

76 FR 51053 - Notice of Public Meetings, Twin Falls District Resource Advisory Council, Idaho

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-17

... afternoon, the RAC will return to the Burley Fire Conference room to discuss Wilderness and Wild and Scenic... Fire Conference Room, located at 3630 Overland Ave., Burley, Idaho 83318. The meeting will begin at 8...

Molecular modeling and residue interaction network studies on the mechanism of binding and resistance of the HCV NS5B polymerase mutants to VX-222 and ANA598.

PubMed

Xue, Weiwei; Jiao, Pingzu; Liu, Huanxiang; Yao, Xiaojun

2014-04-01

Hepatitis C virus (HCV) NS5B protein is an RNA-dependent RNA polymerase (RdRp) with essential functions in viral genome replication and represents a promising therapeutic target to develop direct-acting antivirals (DAAs). Multiple nonnucleoside inhibitors (NNIs) binding sites have been identified within the polymerase. VX-222 and ANA598 are two NNIs targeting thumb II site and palm I site of HCV NS5B polymerase, respectively. These two molecules have been shown to be very effective in phase II clinical trials. However, the emergence of resistant HCV replicon variants (L419M, M423T, I482L mutants to VX-222 and M414T, M414L, G554D mutants to ANA598) has significantly decreased their efficacy. To elucidate the molecular mechanism about how these mutations influenced the drug binding mode and decreased drug efficacy, we studied the binding modes of VX-222 and ANA598 to wild-type and mutant polymerase by molecular modeling approach. Molecular dynamics (MD) simulations results combined with binding free energy calculations indicated that the mutations significantly altered the binding free energy and the interaction for the drugs to polymerase. The further per-residue binding free energy decomposition analysis revealed that the mutations decreased the interactions with several key residues, such as L419, M423, L474, S476, I482, L497, for VX-222 and L384, N411, M414, Y415, Q446, S556, G557 for ANA598. These were the major origins for the resistance to these two drugs. In addition, by analyzing the residue interaction network (RIN) of the complexes between the drugs with wild-type and the mutant polymerase, we found that the mutation residues in the networks involved in the drug resistance possessed a relatively lower size of topology centralities. The shift of betweenness and closeness values of binding site residues in the mutant polymerase is relevant to the mechanism of drug resistance of VX-222 and ANA598. These results can provide an atomic-level understanding about

Targeting Prostate Cancer with Bifunctional Modulators of the Androgen Receptor

DTIC Science & Technology

2014-10-01

androgen receptor/coactivator disruptors. ACS Chem. Biol. 2009, 4, 435–440. (7) Guenther, M.; Barak , O.; Lazar, M. The SMRT and N-CoR corepressors are...17) Welsbie, D. S.; Xu, J.; Chen, Y.; Borsu, L.; Scher, H. I.; Rosen , N.; Sawyers, C. L. Histone deacetylases are required for androgen receptor...J.; Di Vizio, D.; Zhang, X.; Albanese, C.; Balk, S.; Chang, C.; Fan, S.; Rosen , E.; Palvimo, J. J.; Jänne, O. A.; Muratoglu, S.; Avantaggiati, M. L

75 FR 76444 - Environmental Impact Statement (EIS) for Construction and Operation of a Panoramic Survey...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-08

..., 3550 Aberdeen Ave., SE., Kirtland AFB, NM 87117- 5776 (Phone: 505-846-4321; e-mail [email protected]kirtland.af.mil ). Bao-Anh Trinh, GS-14, DAF, Air Force Federal Register Liaison Officer. [FR Doc. 2010...

Plating Inc. Site Fact Sheet: EPA to Begin Cleanup of Hazardous Waste

EPA Pesticide Factsheets

Hazardous waste cleanup and local community outreach around the Plating Inc. site at 888 N. Prior Ave.in St. Paul. The former industrial facility specialized in zinc and chromate plating of aluminum and is now abandoned.

77 FR 3766 - Agency Information Collection Activities; Proposed Collection; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-25

... Constitution Ave. NW., Washington, DC. Attention: Docket ID Number EPA-HQ-OPPT-2011-0777. The DCO is open from..., and submit this information to EPA. EPA uses this information to construct a complete picture of the...

5. Historic American Buildings Survey Frank O. Branzetti, Photographer July ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

5. Historic American Buildings Survey Frank O. Branzetti, Photographer July 8, 1940 (ff) 4- MILE STONE, opp. 862 HUNTINGTON AVE., ROXBURY - Milestones D, Y, Z, AA, BB, FF & NN, Various Roxbury locations, Roxbury, Suffolk County, MA

3. Historic American Buildings Survey Frank O. Branzetti, Photographer July ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

3. Historic American Buildings Survey Frank O. Branzetti, Photographer July 17, 1940 (d) 4- MILE STONE, 471 BLUE HILL AVE., ROXBURY - Milestones D, Y, Z, AA, BB, FF & NN, Various Roxbury locations, Roxbury, Suffolk County, MA

4. Historic American Buildings Survey Frank O. Branzetti, Photographer July ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

4. Historic American Buildings Survey Frank O. Branzetti, Photographer July 23, 1940 (iii) 6- MILE STONE, opp. 1280 BLUE HILL AVE., DORCHESTER - Milestones A, B, E, HHH, III & PPP, Various Dorchester locations, Dorchester, Suffolk County, MA

75 FR 66757 - Stakeholder Input; Listening Session Seeking Suggestions for Improving the Next National...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-29

..., 1301 Constitution Ave., NW., Washington, DC. The Public Reading Room is open from 8:30 a.m. to 4:30 p.m... leachate from anti-fouling hull coatings; aqueous film forming foam (AFFF); boiler/economizer blowdown...

NPDES Permit for National World War II Memorial

EPA Pesticide Factsheets

Under National Pollutant Discharge Elimination System permit number DC0000345, the National World War II Memorial is authorized to discharge from a facility located at 17th St. and Independence Ave., S.W. Washington DC 20024.

75 FR 65013 - Access in Litigation to Confidential Business Information

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-21

..., Office of Site Remediation Enforcement, U.S. Environmental Protection Agency, 1200 Pennsylvania Ave., NW...; Lancaster Laboratories; Lata-Kemron Remediation, LLC; Laucks Testing Laboratories, Incorporated; Liberty...; Metcalf & Eddy, Incorporated; Mitkem Laboratories; NewFields; OHM Remediation Services Corporation...

Large-scale recumbent isoclinal folds in the footwall of the West Cycladic Detachment System (Greece)

NASA Astrophysics Data System (ADS)

Rice, A. Hugh N.; Grasemann, Bernhard

2017-04-01

The Pindos Zone in the Cyclades underwent Eocene high-pressure metamorphism and syn-orogenic exhumation, overprinted by Miocene low-angled extension. Although this represents a combination of likely high-strain-events, structural evidence of large-scale folding is rare. Here potential examples of such folding on Kea and Kythnos, in the Western Cyclades, are evaluated. These islands lie within the Cycladic Blueschist Nappe (lower nappe) of the Pindos Zone and in the footwall of the top-to-SSW West Cycladic Detachment System (WCDS). On Kea, no lithostratigraphy can be established in the 450 m thick greenschist facies mixed sedimentary-volcanoclastic-marble mylonite/phyllonite succession. On the east side of the island, lensoid marble layers frequently bifurcate, which might be reflecting early, sheared-out isoclinal folding, although no evidence of folded compositional layering has been found in potential fold-hinge zones and the bifurcation points are not arranged in a way suggestive of a fold axes parallel to the NNE-SSW oriented stretching lineation. However, at two localities, medium-scale recumbent isoclinal folding has been mapped, with NNE-SSW fold-axes exposed for up to 250 m and amplitudes of up to 170 m. On Kythnos, stretching lineations in greenschist facies rocks show a rotation from ENE-WSW in the north to NNE-SSW in the south, taken to represent a reorientation of the Eocene exhumation strain during block rotation coincident with top-to-SSW movement of the WCDS. The distribution of the three marble units that crop out in central/southern Kythnos suggest large-scale, likely isoclinal folding occurred. (1) Petroussa Lithodeme - a blue-grey calcite (BGC) marble with quartz-calcite-white-mica (QCWM) schists, forming a continuous outcrop around the island, thinning from >16m in the SE to <8m thick mylonites in the SW, overlain by grey sericite-albite-graphite-schists (Flabouria Lithodeme); (2) Rizou Lithodeme - massive grey to BGC marble, with abundant

Validity of Bartram's Painted Vulture (Aves: Cathartidae).

PubMed

Snyder, Noel F R; Fry, Joel T

2013-02-07

William Bartram described the Painted Vulture (Vultur sacra) as a new species in his 1791 book on travels in Florida and other southeastern states. However, no specimen of this bird survives, and it has not been reported by any subsequent ornithologist. Bartram's detailed description is not presently endorsed by the American Ornithologists' Union and has been widely regarded as a myth, a misdescribed King Vulture Sarcoramphus papa (Linnaeus), a misdescribed Northern Caracara Caracara cheriway (Jacquin), or a garbled mixture of species. In fact, his description bears almost no resemblance to a Northern Caracara, but it does match the King Vulture in all important respects except tail color (which is uniform dark brown in all ages and sexes of King Vultures but was white with a dark brown or black tip in Bartram's description). Most 20th century ornithologists commenting on Bartram's bird have been reluctant to accept his description because of the tail-color discrepancy. Only McAtee (1942) concluded that his description could be fully accurate as written, indicating a bird closely related to, but different from, a typical King Vulture. Paralleling Bartram's description is an apparently independent account and painting of a vulture of uncertain geographic origin by Eleazar Albin (1734). Details of Albin's description, including tail color, are very similar to those of Bartram's description. The only discrepancies are minor differences in color of softparts and tail that seem explicable as intraspecific variation. Available evidence suggests that Bartram knew nothing of Albin's description, and if so, Albin's bird provides quite persuasive support for the validity of Bartram's bird. Equally important, none of the arguments offered historically against the validity of the Painted Vulture is persuasive when examined closely. Together, these and other factors make a strong case for acceptance of Bartram's Painted Vulture as a historic resident of northern Florida and likely other adjacent regions.

AVE/VAS 4: 25-mb sounding data

NASA Technical Reports Server (NTRS)

Sienkiewicz, M. E.

1983-01-01

The rawinsonde sounding program is described and tabulated data at 25 mb intervals for the 24 stations and 14 special stations participating in the experiment is presented. Sounding were taken at 3 hr intervals. An additional sounding was taken at the normal synoptic observation time. Some soundings were computed from raw ordinate data, while others were interpolated from significant level data.

76 FR 37773 - Central Montana Resource Advisory Committee

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-28

... will meet in Stanford, MT. The committee is authorized under the Secure Rural Schools and Community... comments must be sent to 109 Central Ave., Stanford, MT 59479, or by e-mail to [email protected] , or via...

76 FR 30094 - Central Montana Resource Advisory Committee

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-24

... will meet in Stanford, MT. The committee is authorized under the Secure Rural Schools and Community... requests for time for oral comments must be sent to 109 Central Ave., Stanford, MT 59479, or by e-mail to...

Sunrayce 97 Continues Day 8 - St. Francis, Kan. to Limon, Colo.

Science.gov Websites

8 - St. Francis, Kan. to Limon, Colo. For more information contact: Patrick Booher, Sunrayce on Colorado Ave. And 24th St. Sunrayce 97 is a solar cross-country event that runs from Indianapolis

77 FR 32169 - SJI Board of Directors Meeting, Notice

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-31

... meeting is to consider grant applications for the 3rd quarter of FY 2012, and other business. All portions of this meeting are open to the public. ADDRESSES: Westin Hotel, 1900 5th Ave., Seattle, WA 98101...

Establishing crash modification factors and their use.

DOT National Transportation Integrated Search

2014-08-01

A critical component in the Association of State Highway and Transportation Officials (AASHTO) Highway Safety Manual : (HSM) safety management process is the Crash Modification Factor (CMF). It is used to estimate the change in the : expected (ave...

78 FR 57655 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-19

... review, we cannot guarantee that we will be able to do so. Dated: August 28, 2013. J. Paul Loether, Chief..., 2216 SE. 32nd Ave., Portland, 13000822 WASHINGTON King County Ford Motor Company Assembly Plant, 4735 E...

Contact Us - Division of Mining, Land, and Water

Science.gov Websites

Lands Coal Regulatory Program Large Mine Permits Mineral Property and Rights Mining Index Land Coal Regulatory Program 550 W. 7th Ave., Suite 900D Anchorage, AK 99501-3577 Phone: (907) 269-8650 Fax

77 FR 102 - Turnbull Hydro LLC; Notice of Application Accepted for Filing for Exemption for a Small Conduit...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-03

... Power Act, 16 U.S.C. 791a-825r. h. Applicant Contact: Ted Sorenson, Sorenson Engineering, 5203 South 11th East, Idaho Falls, ID 83404, (208) 522-8069; Nicholas E. Josten, GeoSense, 2742 Saint Charles Ave...

Economic and quality of life impacts of route 21 freeway construction : final report, October 2009.

DOT National Transportation Integrated Search

2009-10-01

Opened to traffic in December 2000, the missing section of the Route 21 Freeway in Clifton : and Passaic (Hope Ave. to the Route 46 Interchange) was designed utilizing the equivalent to : the Context Sensitive Solutions (CSS) approach at ...

40 CFR 763.173 - Exemptions.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT ASBESTOS Prohibition of the Manufacture, Importation, Processing, and Distribution in Commerce of Certain Asbestos... Pennsylvania Ave., NW., Washington, DC 20460, ATTENTION: Asbestos Exemption. For information regarding the...

THE INTEGRATED USE OF COMPUTATIONAL CHEMISTRY, SCANNING PROBE MICROSCOPY, AND VIRTUAL REALITY TO PREDICT THE CHEMICAL REACTIVITY OF ENVIRONMENTAL SURFACES

EPA Science Inventory

In the last decade three new techniques scanning probe microscopy (SPM), virtual reality (YR) and computational chemistry ave emerged with the combined capability of a priori predicting the chemically reactivity of environmental surfaces. Computational chemistry provides the cap...

Stuccoed building within greenhouse complex, north and west (front) sides, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Stuccoed building within greenhouse complex, north and west (front) sides, looking south towards building no. 121 (tennis courts) across W. Pennington Ave. - Fitzsimons General Hospital, Greenhouse, West Pennington Avenue, East of Building No. 139, Aurora, Adams County, CO

Waterborne Transportation Lines of the United States

DTIC Science & Technology

1988-10-01

C. OUPLANTI! ICO. INC. 3P. C. -0,N 725 I CUNA LA 71161 13 ; 1PrKMNAANE COOP. I2001 MARCUS AVE . ILANE SUCCESS 4Y 1114? 29i APRN TINUI% CU. !ATTN? CAIRN...LANE WEALSO 00 9942. tI I TI 333L06ALj o %EWhSLVA LA ?0114As, Ja3ft4iS p,*v 13 I ATTA, toAL. 1P. 0. -01 Isq3 I A4TIM-1 CA 1I.V31 Al’ hA. II * AV , (1 1...0NM .li. :01 IS. 179 XENTOCVT LIII P3CK CO.. I 1.0 9 170 9~~~ 9 439 14411 9 9 I I -MI "SO,09 -I9**i C W. .IS 13 IT.*92 O L* O4 00111 I I AVE . I

Mesoscale and severe storms (Mass) data management and analysis system

NASA Technical Reports Server (NTRS)

Hickey, J. S.; Karitani, S.; Dickerson, M.

1984-01-01

Progress on the Mesoscale and Severe Storms (MASS) data management and analysis system is described. An interactive atmospheric data base management software package to convert four types of data (Sounding, Single Level, Grid, Image) into standard random access formats is implemented and integrated with the MASS AVE80 Series general purpose plotting and graphics display data analysis software package. An interactive analysis and display graphics software package (AVE80) to analyze large volumes of conventional and satellite derived meteorological data is enhanced to provide imaging/color graphics display utilizing color video hardware integrated into the MASS computer system. Local and remote smart-terminal capability is provided by installing APPLE III computer systems within individual scientist offices and integrated with the MASS system, thus providing color video display, graphics, and characters display of the four data types.

Kinetic energy budgets in areas of intense convection

NASA Technical Reports Server (NTRS)

Fuelberg, H. E.; Berecek, E. M.; Ebel, D. M.; Jedlovec, G. J.

1980-01-01

A kinetic energy budget analysis of the AVE-SESAME 1 period which coincided with the deadly Red River Valley tornado outbreak is presented. Horizontal flux convergence was found to be the major kinetic energy source to the region, while cross contour destruction was the major sink. Kinetic energy transformations were dominated by processes related to strong jet intrusion into the severe storm area. A kinetic energy budget of the AVE 6 period also is presented. The effects of inherent rawinsonde data errors on widely used basic kinematic parameters, including velocity divergence, vorticity advection, and kinematic vertical motion are described. In addition, an error analysis was performed in terms of the kinetic energy budget equation. Results obtained from downward integration of the continuity equation to obtain kinematic values of vertical motion are described. This alternate procedure shows promising results in severe storm situations.

2. SITE OVERVIEW. PART 2 OF 4 PART PANORAMA WITH ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. SITE OVERVIEW. PART 2 OF 4 PART PANORAMA WITH NOS. CA-265-1 TO CA-265-4. INTERCHANGE OF ARROYO SECO PARKWAY, INTERSTATE 1-5, AND FIGUEROA STREET AT CROSSINGS OF THE LOS ANGELES RIVER AS SEEN FROM GRAND VIEW POINT IN ELYSIAN PARK. VIEW 2 SHOWS LOS ANGELES RIVER AND FIGUEROA STREET BRIDGE IN FOREGROUND; INTERSTATE I-5 AT CENTER; AND ARROYO SECO PARKWAY AT RIGHT. LOOKING 30° NNE. - Arroyo Seco Parkway, Los Angeles to Pasadena, Los Angeles, Los Angeles County, CA

Summary of Meteorological Observations, Surface (SMOS) Beaufort, South Carolina.

DTIC Science & Technology

1984-08-01

WATHER N 0? 33 SOO -___ 22$ 75 2ses _1590 NNE 303 *.q lt 17.6 9.9 *7.3 3.1 NE 5*P J.__ 1.? 13.8 $.4 39.7 1 3.9 ENE 1*$ ..s _____7_ 129S S9 55.4 25.0... WATHER SERVC[ OETACHMENT DAILY AVERAGE/EXTREME TEMPERATURES ASHEVILLE. N’ORTH CAROLINA AIP ft 1A o £VrIB*OI ~ mAWSMO £WiIlS O.I OA9 ’C 0 066 0*__ _ 0

New Approaches to Planning for Emerging Long Term Threats. Volume 1. Text

DTIC Science & Technology

1993-12-01

aoaleuon of eudornmn. Wakx* au gd ~ fq~o re 1,c 1e n g e Oftburden. flo Washboon Hoodquernere Services. Oireclareft far hda "m &W a121v iani ann Oper Nne n...are fast-acting, short-lived in the environment, and yield no known toxic breakdown products.22 But because they are based on hydrofluoric acid , they...pose severe hazards to humans in the immediate target area who may come into contact I with the agent before it breaks down. Hydrofluoric acid (and the

76 FR 72383 - Atlantic Highly Migratory Species; Atlantic Shark Management Measures

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-23

... 57709), to 5 p.m. on March 31, 2012. ADDRESSES: Workshops will be held in Madeira Beach, FL; Cocoa Beach... Ave., Cocoa Beach, FL 32931. December 13, 2011 5-8 p.m Gulf Beaches Public 200 Municipal Dr., Madeira...

78 FR 9789 - Airworthiness Directives; Schweizer Aircraft Corporation

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-12

... Certification Office, Engine & Propeller Directorate, 1600 Stewart Ave., suite 410, Westbury, NY 11590... inspection panel kit and stabilizer mount doublers. The Type Certificate for these helicopters transferred...: Stephen Kowalski, Aviation Safety Engineer, New York Aircraft Certification Office, Engine & Propeller...

77 FR 74825 - Information Collection: Federal and Non-Federal Financial Assistant Instruments

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-18

... recipient's accounting system and financial management capabilities. In addition to FFA, Congress created... addressed to Clark Woolley, USDA Forest Service, Director of Acquisitions Management, 1400 Independence Ave... INFORMATION CONTACT: Clark Woolley, Acquisitions Management, 703-605-4654. Individuals who use...