Sample records for kasmel kandela puss
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PU/SS EUTECTIC ASSESSMENT IN 9975 PACKAGINGS IN A STORAGE FACILITY DURING EXTENDED FIRE
DOE Office of Scientific and Technical Information (OSTI.GOV)
Gupta, N.
2012-03-26
In a radioactive material (RAM) packaging, the formation of eutectic at the Pu/SS (plutonium/stainless steel) interface is a serious concern and must be avoided to prevent of leakage of fissile material to the environment. The eutectic temperature for the Pu/SS is rather low (410 C) and could seriously impact the structural integrity of the containment vessel under accident conditions involving fire. The 9975 packaging is used for long term storage of Pu bearing materials in the DOE complex where the Pu comes in contact with the stainless steel containment vessel. Due to the serious consequences of the containment breach atmore » the eutectic site, the Pu/SS interface temperature is kept well below the eutectic formation temperature of 410 C. This paper discusses the thermal models and the results for the extended fire conditions (1500 F for 86 minutes) that exist in a long term storage facility and concludes that the 9975 packaging Pu/SS interface temperature is well below the eutectic temperature.« less
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ERIC Educational Resources Information Center
Andreae, John H.; Cleary, John G.
1976-01-01
The new mechanism, PUSS, enables experience of any complex environment to be accumulated in a predictive model. PURR-PUSS is a teachable robot system based on the new mechanism. Cumulative learning is demonstrated by a detailed example. (Author)
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"Shrek 2:" An Appraisal of Mainstream Animation's Influence on Identity
ERIC Educational Resources Information Center
Pimentel, Octavio; Velazquez, Paul
2009-01-01
This article examines the discursive practices presented in "Shrek 2." We apply a critical discourse analysis lens while focusing on the way animated versions of Latinos and African Americans are portrayed. In particular, the essay focuses on Shrek, Donkey, and Puss-in-Boots and the various stereotypical language discourses they reproduce. The…
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Aircraft Accident Investigation at ARL: The First 50 Years
1993-03-01
monoplane with vee strut bracing. Designed by De Havillands as the DH . 80A, it proved highly successful; two hundred and sixty were built in the UK...3 4. THE PUSS MOTH ACCIDENTS ............................................................ 5 5. THE DH .86 ACCIDENTS...Melbourne and just as the royal procession was turning from St Kilda Road into the grounds of Government House, two DH .9 aircraft of the RAAF flypast collided
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The Use of Tailored Testing with Instructional Programs.
1986-03-01
AVAILABILITY OF REPORT Approved for public release: distribution un- t~X DWNCADNGSCHiEDULE li-mited. Reproduction in whole or in part is...of Education ,-’ Washington, DC 20V 0 Chicago, IL r06 Air Force Human Resources Lab Cdt. Arnold Bohrer . AFHRL/MPD Sectie Psychologisch Cnderzoek...University of Texas-Austin Univ-ir-tat Puss-ldorf Measurement and Evalu-,tion Er zi, gswi ssensch;ftl iches Cpnter Un ivf rsit ’tsst r. 1 Austin, TX 787
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1984-05-01
Field, CA 94035 (415) 965-5892 Mr. James B. Johnson Southwest Research Institute San Antonio, TX 78284 465-70- 7845 Dr. Dean Mook Office of...opponent would puss «?* ch other almost head on. The pilot of aircraft 2 is never looking into his opponent firing cone until his first missile bits...attack and sideslip (on each half of the delta wing). EFF ’EFT arc tan (tana s;:. 0) (2) It can be seen is the induced side compare the C/(.)- ch
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Charles Dicken’s Use of Folklore: A Study of Elements in Bleak House
1981-04-21
witchcraft . This association is first seen In Bleak House when the son of Chancery is identified as the accoutarit-general and Chancery’ father 1 i ’,i,’wi...story of Little Red Riding Hood had undertones of witchcraft md cannibalism, Esther’s other offering, "Puss N1’ Boots," was concerned with a helpful...since the early days of the church and as a result of this association, Jews had a reputation for practicing evil and witchcraft (114/108). Reference
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Ifinedo, Princely
2016-03-01
The purpose of this study was to educate on the moderating effects of demographic (i.e., educational level and age) and individual characteristics (i.e., years of nursing experience and computer knowledge) on nurses' acceptance of information systems (IS). The technology acceptance model (TAM) with its constituent variables such as perceived usefulness (PUSS) and perceived ease of use (PEOU) was the theoretical framework used for this study. A cross-sectional study was conducted in Nova Scotia, Canada. Usable data was collected from 197 registered nurses (RNs). Relevant hypotheses were formulated and the partial least squares (PLS) technique was used for data analysis. The results of the hypothesized relationships showed that education and computer knowledge have positive moderating effects on the influences of PEOU and PUSS on nurses' attitudes toward IS (ATTI). The factors of nurses' years of nursing experience and age did not yield meaningful results. ATTI impacted behavioral intentions to use IS, which positively impacted nurses' use of IS. The nurses sampled in the study have positive IS use behaviors. This study demonstrates that relevant demographic factors and individual characteristics, if incorporated into frameworks used for investigating nurses' acceptance of IS, could permit the emergence of useful insights for practitioners and researchers. Specifically, this study showed that nurses with higher educational attainments and more basic computer knowledge readily accept implemented IS at work. Hospital administrators benefit from insights such as the one presented in this study. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.
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Alternative Optical Architectures for Multichannel Adaptive Optical Processing
1993-04-01
0j +,de 2; j__ -L12 izi j=#1 Pj F2VSIm YS F2 vdI ) N X exp[,2 x (,j + fF,)t]w.-- akx 2 f Fxxp(-j2Xskr W, (16)fsL 2Iu(-LJ:aherir F2VsIJX( 2 fk))r(6 ka...1:512) -off-we); Puss (offset) -1; Rl-Puls8. *31n(2*pi* ([1: 2048 )4phaisrr ./10.24); sukx1la±(221) ,plM (Rl) tit~le ( ’sen chanrnel niqual’) U~sin loop
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Liu, Yanning; Lou, Guohua; Norton, John T; Wang, Chen; Kandela, Irawati; Tang, Shuai; Shank, Nathaniel I; Gupta, Pankaj; Huang, Min; Avram, Michael J; Green, Richard; Mazar, Andrew; Appella, Daniel; Chen, Zhi; Huang, Sui
2017-12-01
Hepatocellular carcinoma (HCC) is the third leading form of cancer worldwide, and its incidence is increasing rapidly in the United States, tripling over the past 3 decades. The current chemotherapeutic strategies against localized and metastatic HCC are ineffective. Here we report that 6-methoxyethylamino-numonafide (MEAN) is a potent growth inhibitor of murine xenografts of 2 human HCC cell lines. At the same dose and with the same treatment strategies, MEAN was more efficacious in inhibiting tumor growth in mice than sorafenib, the only approved drug for HCC. Treatment by MEAN at an effective dose for 6 wk was well tolerated by animals. Combined therapy using both sorafenib and MEAN enhanced tumor growth inhibition over monotherapy with either agent. Additional experiments revealed that MEAN inhibited tumor growth through mechanisms distinct from those of either its parent compound, amonafide, or sorafenib. MEAN suppressed C-MYC expression and increased expression of several tumor suppressor genes, including Src homology region 2 domain-containing phosphatase-1 ( SHP-1 ) and TXNIP (thioredoxin-interacting protein). As an encouraging feature for envisioned clinical application, the IC 50 of MEAN was not significantly changed in several drug-resistant cell lines with activated P-glycoprotein drug efflux pumps compared to drug-sensitive parent cells, demonstrating the ability of MEAN to be effective in cells resistant to existing chemotherapy regimens. MEAN is a promising candidate for clinical development as a single-agent therapy or in combination with sorafenib for the management of HCC.-Liu, Y., Lou, G., Norton, J. T., Wang, C., Kandela, I., Tang, S., Shank, N. I., Gupta, P., Huang, M., Avram, M. J., Green, R., Mazar, A., Appella, D., Chen, Z., Huang, S. 6-Methoxyethylamino-numonafide inhibits hepatocellular carcinoma xenograft growth as a single agent and in combination with sorafenib. © FASEB.
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Triggerable Degradation of Polyurethanes for Tissue Engineering Applications.
Xu, Cancan; Huang, Yihui; Wu, Jinglei; Tang, Liping; Hong, Yi
2015-09-16
Tissue engineered and bioactive scaffolds with different degradation rates are required for the regeneration of diverse tissues/organs. To optimize tissue regeneration in different tissues, it is desirable that the degradation rate of scaffolds can be manipulated to comply with various stages of tissue regeneration. Unfortunately, the degradation of most degradable polymers relies solely on passive controlled degradation mechanisms. To overcome this challenge, we report a new family of reduction-sensitive biodegradable elastomeric polyurethanes containing various amounts of disulfide bonds (PU-SS), in which degradation can be initiated and accelerated with the supplement of a biological product: antioxidant-glutathione (GSH). The polyurethanes can be processed into films and electrospun fibrous scaffolds. Synthesized materials exhibited robust mechanical properties and high elasticity. Accelerated degradation of the materials was observed in the presence of GSH, and the rate of such degradation depends on the amount of disulfide present in the polymer backbone. The polymers and their degradation products exhibited no apparent cell toxicity while the electrospun scaffolds supported fibroblast growth in vitro. The in vivo subcutaneous implantation model showed that the polymers prompt minimal inflammatory responses, and as anticipated, the polymer with the higher disulfide bond amount had faster degradation in vivo. This new family of polyurethanes offers tremendous potential for directed scaffold degradation to promote maximal tissue regeneration.
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Davidson Jebaseelan, D; Jebaraj, C; Yoganandan, N; Rajasekaran, S; Yerramshetty, J
2014-07-01
Growth modulation changes occur in pediatric spines and lead to kyphotic deformity during discitis infection from mechanical forces. The present study was done to understand the consequences of discitis by simulating inflammatory puss at the T12/L1 disc space using a validated eight-year-old thoracolumbar spine finite element model. Changes in the biomechanical responses of the bone, disc and ligaments were determined under physiological compression and flexion loads in the intact and discitis models. During flexion, the angular-displacement increased by 3.33 times the intact spine and localized at the infected junction (IJ). The IJ became a virtual hinge. During compression loading, higher stresses occurred in the growth plate superior to the IJ. The components of the principal stresses in the growth plates at the T12/L1 junction indicated differential stresses. The strain increased by 143% during flexion loading in the posterior ligaments. The study indicates that the flexible pediatric spine increases the motion of the infected spine during physiological loadings. Understanding intrinsic responses around growth plates is important within the context of growth modulation in children. These results are clinically relevant as it might help surgeons to come up with better decisions while developing treatment protocols or performing surgeries. Copyright © 2014 IPEM. Published by Elsevier Ltd. All rights reserved.
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Curvularia abscess of the brainstem.
Skovrlj, Branko; Haghighi, Maryam; Smethurst, Mark E; Caridi, John; Bederson, Joshua B
2014-01-01
To present a unique case of a brainstem Curvularia fungal infection and review the diagnosis and management of this rare phenomenon. A 33-year-old immunocompetent African American male presented with 2 weeks of headache, nausea, and vomiting in a setting of a recent 20-lb weight loss. Neurological examination was positive for multiple cranial nerve palsies, hemisensory loss, and gait instability. Magnetic resonance imaging demonstrated an enhancing medullary lesion. Metastatic and infectious workup revealed a left lung lesion, which on subsequent biopsy was positive for a granuloma yielding no further clues to the etiology of the brainstem lesion. On surgical exploration of the cranial lesion, a puss-filed, encapsulated lesion was encountered that was tightly adherent to the brainstem. Intraoperative biopsy of the lesion capsule was initially negative but on postoperative day 9, fungal hyphae were encountered identified on morphology as Curvularia species. The patient was started on triple antifungal therapy but necessitated a second surgery for lesion debulking and drainage. The patient was discharged home 10 weeks after initial presentation. At the 13-months follow-up the patient is doing very well and his neurological examination continues to improve. This is the first reported case of a brainstem Curvularia infection. This case highlights the importance of an aggressive surgical and antibiotic therapy in the treatment of central nervous system Curvularia infections. There appears to be a strong relationship between heavy marijuana use and Curvularia infection, producing lung granulomas that may extend to other organs such as the central nervous system of immunocompetent patients. Copyright © 2014 Elsevier Inc. All rights reserved.
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[Handling the cases of school failure in an educational institute in Zaghouan].
Abdelkafi Koubaa, Afifa; Bouslama, Samira; Bel Abed, Najet; Dahmen, Hayet; Mira Gabsi, Zvine; Gabsi, Abdallah; Ouerfelli, Nabil; Mabaouj, Mohamed Taher; Bachouche, Imen
2011-10-01
To assess the main reasons for the school failure in a school in Zaghouan, how to handle these issues, to evaluate the work of the school social office. A retrospective study included 86 failure cases in a school in Zaghouan, handled by the school social office for three years (2004 - 2007). He have detected the principals causes of school failure, detected by the educational staff or by the listening office. The causes of failure are mainly social (46%) as family problems and low income. These families received financial aids and free treatment cards. Discussions have been made with the parents in order to make them more conscious. The pedagogical reasons (28%) however are usually relationship' problems between the student and his teacher or the student and the administration, the three subjects were informed so that attitudes could be changed in the purpose of helping the student. Twelve students (14%) have a psychological case, depression and over worrying, led in some cases to addiction.These cases were diagnosed and transferred to specialized clinics.Sense and chronic diseases (12%), are considered as health reasons for school failure and caused several absences in the school. The school physicist took care of these cases by handling them medical guidance cards while observing the diagnose progress. As school results, 56 cases turned satisfaisant which is 65 % of all cases. The school failure became a priority of the "School Health" institute. That puss to create the school social program, his aim is protecting the students from all dangers, early school leaving and social disintegration, and delinquency. Thus, all parts must be responsible for the school failure, teachers, parents, students,psychiatrists and physicists, as well as introducing the social school work and listening offices and missions to the parents, students and teachers in order to guarantee the success of the operations.