The 16 August 1997 Novaya Zemlya seismic event as viewed from GSN stations KEV and KBS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hartse, H.E.

1997-11-01

Using current and historic seismic records from Global Seismic Network stations KEV and KBS, the authors find that S minus P arrival time comparisons between nuclear explosions and the 16 August 1997 seismic event (m{sub b} {approx} 3.6) from near Novaya Zemlya clearly indicate that (relative to KEV) the 16 August event occurred at least 80 km east of the Russian test site. Including S minus P arrival times from KBS constrains the location to beneath the Kara Sea and in good agreement with previously reported locations, over 100 km southeast of the test site. From an analysis of P{submore » n}/S{sub n} waveform ratios at frequencies above 4 Hz, they find that the 16 August event falls within the population of regional earthquakes and is distinctly separated from Novaya Zemlya and other northern Eurasian nuclear explosion populations. Thus, given its location and waveform characteristics, they conclude the 16 August event was an earthquake. The 16 August event was not detected at teleseismic distances, and thus, this event provides a good example of the regional detection, location, and identification efforts that will be required to monitor the Comprehensive Test Ban Treaty below m{sub b} {approx} 4.« less

Traits and types of health data repositories.

PubMed

Wade, Ted D

2014-01-01

We review traits of reusable clinical data and offer a typology of clinical repositories with a range of known examples. Sources of clinical data suitable for research can be classified into types reflecting the data's institutional origin, original purpose, level of integration and governance. Primary data nearly always come from research studies and electronic medical records. Registries collect data on focused populations primarily to track outcomes, often using observational research methods. Warehouses are institutional information utilities repackaging clinical care data. Collections organize data from more organizations than a data warehouse, and more original data sources than a registry. Therefore even if they are heavily curated, their level of internal integration, and thus ease of use, can be less than other types. Federations are like collections except that physical control over data is distributed among donor organizations. Federations sometimes federate, giving a second level of organization. While the size, in number of patients, varies widely within each type of data source, populations over 10 K are relatively numerous, and much larger populations can be seen in warehouses and federations. One imagined ideal structure for research progress has been called an "Information Commons". It would have longitudinal, multi-leveled (environmental through molecular) data on a large population of identified, consenting individuals. These are qualities whose achievement would require long term commitment on the part of many data donors, including a willingness to make their data public.

Coupling fuel cycles with repositories: how repository institutional choices may impact fuel cycle design

DOE Office of Scientific and Technical Information (OSTI.GOV)

Forsberg, C.; Miller, W.F.

2013-07-01

The historical repository siting strategy in the United States has been a top-down approach driven by federal government decision making but it has been a failure. This policy has led to dispatching fuel cycle facilities in different states. The U.S. government is now considering an alternative repository siting strategy based on voluntary agreements with state governments. If that occurs, state governments become key decision makers. They have different priorities. Those priorities may change the characteristics of the repository and the fuel cycle. State government priorities, when considering hosting a repository, are safety, financial incentives and jobs. It follows that statesmore » will demand that a repository be the center of the back end of the fuel cycle as a condition of hosting it. For example, states will push for collocation of transportation services, safeguards training, and navy/private SNF (Spent Nuclear Fuel) inspection at the repository site. Such activities would more than double local employment relative to what was planned for the Yucca Mountain-type repository. States may demand (1) the right to take future title of the SNF so if recycle became economic the reprocessing plant would be built at the repository site and (2) the right of a certain fraction of the repository capacity for foreign SNF. That would open the future option of leasing of fuel to foreign utilities with disposal of the SNF in the repository but with the state-government condition that the front-end fuel-cycle enrichment and fuel fabrication facilities be located in that state.« less

Long-term geochemical evolution of the near field repository: Insights from reactive transport modelling and experimental evidences

NASA Astrophysics Data System (ADS)

Arcos, David; Grandia, Fidel; Domènech, Cristina; Fernández, Ana M.; Villar, María V.; Muurinen, Arto; Carlsson, Torbjörn; Sellin, Patrik; Hernán, Pedro

2008-12-01

The KBS-3 underground nuclear waste repository concept designed by the Swedish Nuclear Fuel and Waste Management Co. (SKB) includes a bentonite buffer barrier surrounding the copper canisters and the iron insert where spent nuclear fuel will be placed. Bentonite is also part of the backfill material used to seal the access and deposition tunnels of the repository. The bentonite barrier has three main safety functions: to ensure the physical stability of the canister, to retard the intrusion of groundwater to the canisters, and in case of canister failure, to retard the migration of radionuclides to the geosphere. Laboratory experiments (< 10 years long) have provided evidence of the control exerted by accessory minerals and clay surfaces on the pore water chemistry. The evolution of the pore water chemistry will be a primordial factor on the long-term stability of the bentonite barrier, which is a key issue in the safety assessments of the KBS-3 concept. In this work we aim to study the long-term geochemical evolution of bentonite and its pore water in the evolving geochemical environment due to climate change. In order to do this, reactive transport simulations are used to predict the interaction between groundwater and bentonite which is simulated following two different pathways: (1) groundwater flow through the backfill in the deposition tunnels, eventually reaching the top of the deposition hole, and (2) direct connection between groundwater and bentonite rings through fractures in the granite crosscutting the deposition hole. The influence of changes in climate has been tested using three different waters interacting with the bentonite: present-day groundwater, water derived from ice melting, and deep-seated brine. Two commercial bentonites have been considered as buffer material, MX-80 and Deponit CA-N, and one natural clay (Friedland type) for the backfill. They show differences in the composition of the exchangeable cations and in the accessory mineral

Long-term geochemical evolution of the near field repository: insights from reactive transport modelling and experimental evidences.

PubMed

Arcos, David; Grandia, Fidel; Domènech, Cristina; Fernández, Ana M; Villar, María V; Muurinen, Arto; Carlsson, Torbjörn; Sellin, Patrik; Hernán, Pedro

2008-12-12

The KBS-3 underground nuclear waste repository concept designed by the Swedish Nuclear Fuel and Waste Management Co. (SKB) includes a bentonite buffer barrier surrounding the copper canisters and the iron insert where spent nuclear fuel will be placed. Bentonite is also part of the backfill material used to seal the access and deposition tunnels of the repository. The bentonite barrier has three main safety functions: to ensure the physical stability of the canister, to retard the intrusion of groundwater to the canisters, and in case of canister failure, to retard the migration of radionuclides to the geosphere. Laboratory experiments (< 10 years long) have provided evidence of the control exerted by accessory minerals and clay surfaces on the pore water chemistry. The evolution of the pore water chemistry will be a primordial factor on the long-term stability of the bentonite barrier, which is a key issue in the safety assessments of the KBS-3 concept. In this work we aim to study the long-term geochemical evolution of bentonite and its pore water in the evolving geochemical environment due to climate change. In order to do this, reactive transport simulations are used to predict the interaction between groundwater and bentonite which is simulated following two different pathways: (1) groundwater flow through the backfill in the deposition tunnels, eventually reaching the top of the deposition hole, and (2) direct connection between groundwater and bentonite rings through fractures in the granite crosscutting the deposition hole. The influence of changes in climate has been tested using three different waters interacting with the bentonite: present-day groundwater, water derived from ice melting, and deep-seated brine. Two commercial bentonites have been considered as buffer material, MX-80 and Deponit CA-N, and one natural clay (Friedland type) for the backfill. They show differences in the composition of the exchangeable cations and in the accessory mineral

The Research Library's Role in Digital Repository Services: Final Report of the ARL Digital Repository Issues Task Force

ERIC Educational Resources Information Center

Association of Research Libraries, 2009

2009-01-01

Libraries are making diverse contributions to the development of many types of digital repositories, particularly those housing locally created digital content, including new digital objects or digitized versions of locally held works. In some instances, libraries are managing a repository and its related services entirely on their own, but often…

Active Exploration of Large 3D Model Repositories.

PubMed

Gao, Lin; Cao, Yan-Pei; Lai, Yu-Kun; Huang, Hao-Zhi; Kobbelt, Leif; Hu, Shi-Min

2015-12-01

With broader availability of large-scale 3D model repositories, the need for efficient and effective exploration becomes more and more urgent. Existing model retrieval techniques do not scale well with the size of the database since often a large number of very similar objects are returned for a query, and the possibilities to refine the search are quite limited. We propose an interactive approach where the user feeds an active learning procedure by labeling either entire models or parts of them as "like" or "dislike" such that the system can automatically update an active set of recommended models. To provide an intuitive user interface, candidate models are presented based on their estimated relevance for the current query. From the methodological point of view, our main contribution is to exploit not only the similarity between a query and the database models but also the similarities among the database models themselves. We achieve this by an offline pre-processing stage, where global and local shape descriptors are computed for each model and a sparse distance metric is derived that can be evaluated efficiently even for very large databases. We demonstrate the effectiveness of our method by interactively exploring a repository containing over 100 K models.

3D numerical modelling of the thermal state of deep geological nuclear waste repositories

NASA Astrophysics Data System (ADS)

Butov, R. A.; Drobyshevsky, N. I.; Moiseenko, E. V.; Tokarev, Yu. N.

2017-09-01

One of the important aspects of the high-level radioactive waste (HLW) disposal in deep geological repositories is ensuring the integrity of the engineered barriers which is, among other phenomena, considerably influenced by the thermal loads. As the HLW produce significant amount of heat, the design of the repository should maintain the balance between the cost-effectiveness of the construction and the sufficiency of the safety margins, including those imposed on the thermal conditions of the barriers. The 3D finite-element computer code FENIA was developed as a tool for simulation of thermal processes in deep geological repositories. Further the models for mechanical phenomena and groundwater hydraulics will be added resulting in a fully coupled thermo-hydro-mechanical (THM) solution. The long-term simulations of the thermal state were performed for two possible layouts of the repository. One was based on the proposed project of Russian repository, and another features larger HLW amount within the same space. The obtained results describe the spatial and temporal evolution of the temperature filed inside the repository and in the surrounding rock for 3500 years. These results show that practically all generated heat was ultimately absorbed by the host rock without any significant temperature increase. Still in the short time span even in case of smaller amount of the HLW the temperature maximum exceeds 100 °C, and for larger amount of the HLW the local temperature remains above 100 °C for considerable time. Thus, the substantiation of the long-term stability of the repository would require an extensive study of the materials properties and behaviour in order to remove the excessive conservatism from the simulations and to reduce the uncertainty of the input data.

15 CFR 1180.10 - NTIS permanent repository.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 15 Commerce and Foreign Trade 3 2010-01-01 2010-01-01 false NTIS permanent repository. 1180.10... ENGINEERING INFORMATION TO THE NATIONAL TECHNICAL INFORMATION SERVICE § 1180.10 NTIS permanent repository. A... repository as a service to agencies unless the Director advises the Liaison Officer that it has not been so...

Klüver–Bucy syndrome associated with a recessive variant in HGSNAT in two siblings with Mucopolysaccharidosis type IIIC (Sanfilippo C)

PubMed Central

Hu, Hao; Hübner, Christoph; Lukacs, Zoltan; Musante, Luciana; Gill, Esther; Wienker, Thomas F; Ropers, Hans-Hilger; Knierim, Ellen; Schuelke, Markus

2017-01-01

Klüver–Bucy syndrome (KBS) comprises a set of neurobehavioral symptoms with psychic blindness, hypersexuality, disinhibition, hyperorality, and hypermetamorphosis that were originally observed after bilateral lobectomy in Rhesus monkeys. We investigated two siblings with KBS from a consanguineous family by whole-exome sequencing and autozygosity mapping. We detected a homozygous variant in the heparan-α-glucosaminidase-N-acetyltransferase gene (HGSNAT; c.518G>A, p.(G173D), NCBI ClinVar RCV000239404.1), which segregated with the phenotype. Disease-causing variants in this gene are known to be associated with autosomal recessive Mucopolysaccharidosis type IIIC (MPSIIIC, Sanfilippo C). This lysosomal storage disease is due to deficiency of the acetyl-CoA:α-glucosaminidase-N-acetyltransferase, which was shown to be reduced in patient fibroblasts. Our report extends the phenotype associated with MPSIIIC. Besides MPSIIIA and MPSIIIB, due to variants in SGSH and NAGLU, this is the third subtype of Sanfilippo disease to be associated with KBS. MPSIII should be included in the differential diagnosis of young patients with KBS. PMID:27827379

Klüver-Bucy syndrome associated with a recessive variant in HGSNAT in two siblings with Mucopolysaccharidosis type IIIC (Sanfilippo C).

PubMed

Hu, Hao; Hübner, Christoph; Lukacs, Zoltan; Musante, Luciana; Gill, Esther; Wienker, Thomas F; Ropers, Hans-Hilger; Knierim, Ellen; Schuelke, Markus

2017-02-01

Klüver-Bucy syndrome (KBS) comprises a set of neurobehavioral symptoms with psychic blindness, hypersexuality, disinhibition, hyperorality, and hypermetamorphosis that were originally observed after bilateral lobectomy in Rhesus monkeys. We investigated two siblings with KBS from a consanguineous family by whole-exome sequencing and autozygosity mapping. We detected a homozygous variant in the heparan-α-glucosaminidase-N-acetyltransferase gene (HGSNAT; c.518G>A, p.(G173D), NCBI ClinVar RCV000239404.1), which segregated with the phenotype. Disease-causing variants in this gene are known to be associated with autosomal recessive Mucopolysaccharidosis type IIIC (MPSIIIC, Sanfilippo C). This lysosomal storage disease is due to deficiency of the acetyl-CoA:α-glucosaminidase-N-acetyltransferase, which was shown to be reduced in patient fibroblasts. Our report extends the phenotype associated with MPSIIIC. Besides MPSIIIA and MPSIIIB, due to variants in SGSH and NAGLU, this is the third subtype of Sanfilippo disease to be associated with KBS. MPSIII should be included in the differential diagnosis of young patients with KBS.

Progress Towards International Repositories

DOE Office of Scientific and Technical Information (OSTI.GOV)

McCombie, C.; Chapman, N.

2002-02-27

The nuclear fuel cycle is designed to be very international, with some specialist activities (e.g. fuel fabrication, reprocessing, etc.) being confined to a few countries. Nevertheless, political and public opposition has in the past been faced by proposals to internationalise the back-end of the cycle, in particular waste disposal. Attitudes, however, have been changing recently and there is now more acceptance of the general concept of shared repositories and of specific proposals such as that of Pangea. However, as for national facilities, progress towards implementation of shared repositories will be gradual. Moreover, the best vehicle for promoting the concept maymore » not be a commercial type of organization. Consequently the Pangea project team are currently establishing a widely based Association for this purpose.« less

Evaluation of Five Sedimentary Rocks Other Than Salt for Geologic Repository Siting Purposes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Croff, A.G.; Lomenick, T.F.; Lowrie, R.S.

The US Department of Energy (DOE), in order to increase the diversity of rock types under consideration by the geologic disposal program, initiated the Sedimary ROck Program (SERP), whose immediate objectiv eis to evaluate five types of secimdnary rock - sandstone, chalk, carbonate rocks (limestone and dolostone), anhydrock, and shale - to determine the potential for siting a geologic repository. The evaluation of these five rock types, together with the ongoing salt studies, effectively results in the consideration of all types of relatively impermeable sedimentary rock for repository purposes. The results of this evaluation are expressed in terms of amore » ranking of the five rock types with respect to their potential to serve as a geologic repository host rock. This comparative evaluation was conducted on a non-site-specific basis, by use of generic information together with rock evaluation criteria (RECs) derived from the DOE siting guidelines for geologic repositories (CFR 1984). An information base relevant to rock evaluation using these RECs was developed in hydrology, geochemistry, rock characteristics (rock occurrences, thermal response, rock mechanics), natural resources, and rock dissolution. Evaluation against postclosure and preclosure RECs yielded a ranking of the five subject rocks with respect to their potential as repository host rocks. Shale was determined to be the most preferred of the five rock types, with sandstone a distant second, the carbonate rocks and anhydrock a more distant third, and chalk a relatively close fourth.« less

Optimizing procedures for a human genome repository

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nierman, W.C.

1991-03-01

Large numbers of clones will be generated during the Human Genome Project. As each is characterized, subsets will be identified which are useful to the scientific community at large. These subsets are most readily distributed through public repositories. The American Type Culture Collection (ATCC) is experienced in repository operation, but before this project had no history in managing clones and associated information in large batches instead of individually. This project permitted the ATCC to develop several procedures for automating and thus reducing the cost of characterizing, preserving, and maintaining information about clones.

Classification of Clinical Research Study Eligibility Criteria to Support Multi-Stage Cohort Identification Using Clinical Data Repositories.

PubMed

Cimino, James J; Lancaster, William J; Wyatt, Mathew C

2017-01-01

One of the challenges to using electronic health record (EHR) repositories for research is the difficulty mapping study subject eligibility criteria to the query capabilities of the repository. We sought to characterize criteria as "easy" (searchable in a typical repository), "hard" (requiring manual review of the record data), and "impossible" (not typically available in EHR repositories). We obtained 292 criteria from 20 studies available from Clinical Trials.gov and rated them according to our three types, plus a fourth "mixed" type. We had good agreement among three independent reviewers and chose 274 criteria that were characterized by single types for further analysis. The resulting analysis showed typical features of criteria that do and don't map to repositories. We propose that these features be used to guide researchers in specifying eligibility criteria to improve development of enrollment workflow, including the definition of EHR repository queries for self-service or analyst-mediated retrievals.

Results of instrument reliability study for high-level nuclear-waste repositories. [Geotechnical parameters

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rogue, F.; Binnall, E.P.

1982-10-01

Reliable instrumentation will be needed to monitor the performance of future high-level waste repository sites. A study has been made to assess instrument reliability at Department of Energy (DOE) waste repository related experiments. Though the study covers a wide variety of instrumentation, this paper concentrates on experiences with geotechnical instrumentation in hostile repository-type environments. Manufacturers have made some changes to improve the reliability of instruments for repositories. This paper reviews the failure modes, rates, and mechanisms, along with manufacturer modifications and recommendations for additional improvements to enhance instrument performance. 4 tables.

Design consideration in constructing high performance embedded Knowledge-Based Systems (KBS)

NASA Technical Reports Server (NTRS)

Dalton, Shelly D.; Daley, Philip C.

1988-01-01

As the hardware trends for artificial intelligence (AI) involve more and more complexity, the process of optimizing the computer system design for a particular problem will also increase in complexity. Space applications of knowledge based systems (KBS) will often require an ability to perform both numerically intensive vector computations and real time symbolic computations. Although parallel machines can theoretically achieve the speeds necessary for most of these problems, if the application itself is not highly parallel, the machine's power cannot be utilized. A scheme is presented which will provide the computer systems engineer with a tool for analyzing machines with various configurations of array, symbolic, scaler, and multiprocessors. High speed networks and interconnections make customized, distributed, intelligent systems feasible for the application of AI in space. The method presented can be used to optimize such AI system configurations and to make comparisons between existing computer systems. It is an open question whether or not, for a given mission requirement, a suitable computer system design can be constructed for any amount of money.

Repository Planning, Design, and Engineering: Part II-Equipment and Costing.

PubMed

Baird, Phillip M; Gunter, Elaine W

2016-08-01

Part II of this article discusses and provides guidance on the equipment and systems necessary to operate a repository. The various types of storage equipment and monitoring and support systems are presented in detail. While the material focuses on the large repository, the requirements for a small-scale startup are also presented. Cost estimates and a cost model for establishing a repository are presented. The cost model presents an expected range of acquisition costs for the large capital items in developing a repository. A range of 5,000-7,000 ft(2) constructed has been assumed, with 50 frozen storage units, to reflect a successful operation with growth potential. No design or engineering costs, permit or regulatory costs, or smaller items such as the computers, software, furniture, phones, and barcode readers required for operations have been included.

Object links in the repository

NASA Technical Reports Server (NTRS)

Beck, Jon; Eichmann, David

1991-01-01

Some of the architectural ramifications of extending the Eichmann/Atkins lattice-based classification scheme to encompass the assets of the full life-cycle of software development are explored. In particular, we wish to consider a model which provides explicit links between objects in addition to the edges connecting classification vertices in the standard lattice. The model we consider uses object-oriented terminology. Thus, the lattice is viewed as a data structure which contains class objects which exhibit inheritance. A description of the types of objects in the repository is presented, followed by a discussion of how they interrelate. We discuss features of the object-oriented model which support these objects and their links, and consider behavior which an implementation of the model should exhibit. Finally, we indicate some thoughts on implementing a prototype of this repository architecture.

Corticotropin, Repository Injection

MedlinePlus

Corticotropin repository injection is used to treat the following conditions:infantile spasms (seizures that usually begin during the first ... of the arms, hands, feet, and legs). Corticotropin repository injection is in a class of medications called ...

A University Library Creates a Digital Repository for Documenting and Disseminating Community Engagement

ERIC Educational Resources Information Center

Miller, William A.; Billings, Marilyn

2012-01-01

Digital repositories are new tools for documenting the accumulated scholarly work produced at academic institutions and disseminating that material broadly via the internet. Digital repositories support all file types and can be adapted to meet the custom design specifications of individual institutions. A section for community engagement…

Repository Collection Policies: Is a Liberal and Inclusive Policy Helpful or Harmful?

ERIC Educational Resources Information Center

Bankier, Jean-Gabriel; Smith, Courtney

2010-01-01

Institutional repositories have been established by most university libraries but their level of success has varied. Determining what belongs in such repositories has been the subject of some discussion but research would suggest that a broader rather than narrower compass is a positive approach to adopt. By seeking out a variety of content types,…

Finite element code FENIA verification and application for 3D modelling of thermal state of radioactive waste deep geological repository

NASA Astrophysics Data System (ADS)

Butov, R. A.; Drobyshevsky, N. I.; Moiseenko, E. V.; Tokarev, U. N.

2017-11-01

The verification of the FENIA finite element code on some problems and an example of its application are presented in the paper. The code is being developing for 3D modelling of thermal, mechanical and hydrodynamical (THM) problems related to the functioning of deep geological repositories. Verification of the code for two analytical problems has been performed. The first one is point heat source with exponential heat decrease, the second one - linear heat source with similar behavior. Analytical solutions have been obtained by the authors. The problems have been chosen because they reflect the processes influencing the thermal state of deep geological repository of radioactive waste. Verification was performed for several meshes with different resolution. Good convergence between analytical and numerical solutions was achieved. The application of the FENIA code is illustrated by 3D modelling of thermal state of a prototypic deep geological repository of radioactive waste. The repository is designed for disposal of radioactive waste in a rock at depth of several hundred meters with no intention of later retrieval. Vitrified radioactive waste is placed in the containers, which are placed in vertical boreholes. The residual decay heat of radioactive waste leads to containers, engineered safety barriers and host rock heating. Maximum temperatures and corresponding times of their establishment have been determined.

Grid Application Meta-Repository System: Repository Interconnectivity and Cross-domain Application Usage in Distributed Computing Environments

NASA Astrophysics Data System (ADS)

Tudose, Alexandru; Terstyansky, Gabor; Kacsuk, Peter; Winter, Stephen

Grid Application Repositories vary greatly in terms of access interface, security system, implementation technology, communication protocols and repository model. This diversity has become a significant limitation in terms of interoperability and inter-repository access. This paper presents the Grid Application Meta-Repository System (GAMRS) as a solution that offers better options for the management of Grid applications. GAMRS proposes a generic repository architecture, which allows any Grid Application Repository (GAR) to be connected to the system independent of their underlying technology. It also presents applications in a uniform manner and makes applications from all connected repositories visible to web search engines, OGSI/WSRF Grid Services and other OAI (Open Archive Initiative)-compliant repositories. GAMRS can also function as a repository in its own right and can store applications under a new repository model. With the help of this model, applications can be presented as embedded in virtual machines (VM) and therefore they can be run in their native environments and can easily be deployed on virtualized infrastructures allowing interoperability with new generation technologies such as cloud computing, application-on-demand, automatic service/application deployments and automatic VM generation.

The Emperor's New Repository

ERIC Educational Resources Information Center

Chudnov, Daniel

2008-01-01

The author does not know the first thing about building digital repositories. Maybe that is a strange thing to say, given that he works in a repository development group now, worked on the original DSpace project years ago, and worked on a few repository research projects in between. Given how long he has been around people and projects aiming to…

Transportation plan repository and archive.

DOT National Transportation Integrated Search

2011-04-01

This project created a repository and archive for transportation planning documents in Texas within the : established Texas A&M Repository (http://digital.library.tamu.edu). This transportation planning archive : and repository provides ready access ...

Audit and Certification Process for Science Data Digital Repositories

NASA Astrophysics Data System (ADS)

Hughes, J. S.; Giaretta, D.; Ambacher, B.; Ashley, K.; Conrad, M.; Downs, R. R.; Garrett, J.; Guercio, M.; Lambert, S.; Longstreth, T.; Sawyer, D. M.; Sierman, B.; Tibbo, H.; Waltz, M.

2011-12-01

Science data digital repositories are entrusted to ensure that a science community's data are available and useful to users both today and in the future. Part of the challenge in meeting this responsibility is identifying the standards, policies and procedures required to accomplish effective data preservation. Subsequently a repository should be evaluated on whether or not they are effective in their data preservation efforts. This poster will outline the process by which digital repositories are being formally evaluated in terms of their ability to preserve the digitally encoded information with which they have been entrusted. The ISO standards on which this is based will be identified and the relationship of these standards to the Open Archive Information System (OAIS) reference model will be shown. Six test audits have been conducted with three repositories in Europe and three in the USA. Some of the major lessons learned from these test audits will be briefly described. An assessment of the possible impact of this type of audit and certification on the practice of preserving digital information will also be provided.

NCI Mouse Repository | FNLCR Staging

Cancer.gov

The NCI Mouse Repository is an NCI-funded resource for mouse cancer models and associated strains. The repository makes strains available to all members of the scientific community (academic, non-profit, and commercial). NCI Mouse Repository strains

40 CFR 124.33 - Information repository.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 21 2010-07-01 2010-07-01 false Information repository. 124.33 Section... FOR DECISIONMAKING Specific Procedures Applicable to RCRA Permits § 124.33 Information repository. (a... basis, for an information repository. When assessing the need for an information repository, the...

Terminology development towards harmonizing multiple clinical neuroimaging research repositories.

PubMed

Turner, Jessica A; Pasquerello, Danielle; Turner, Matthew D; Keator, David B; Alpert, Kathryn; King, Margaret; Landis, Drew; Calhoun, Vince D; Potkin, Steven G; Tallis, Marcelo; Ambite, Jose Luis; Wang, Lei

2015-07-01

Data sharing and mediation across disparate neuroimaging repositories requires extensive effort to ensure that the different domains of data types are referred to by commonly agreed upon terms. Within the SchizConnect project, which enables querying across decentralized databases of neuroimaging, clinical, and cognitive data from various studies of schizophrenia, we developed a model for each data domain, identified common usable terms that could be agreed upon across the repositories, and linked them to standard ontological terms where possible. We had the goal of facilitating both the current user experience in querying and future automated computations and reasoning regarding the data. We found that existing terminologies are incomplete for these purposes, even with the history of neuroimaging data sharing in the field; and we provide a model for efforts focused on querying multiple clinical neuroimaging repositories.

Terminology development towards harmonizing multiple clinical neuroimaging research repositories

PubMed Central

Turner, Jessica A.; Pasquerello, Danielle; Turner, Matthew D.; Keator, David B.; Alpert, Kathryn; King, Margaret; Landis, Drew; Calhoun, Vince D.; Potkin, Steven G.; Tallis, Marcelo; Ambite, Jose Luis; Wang, Lei

2015-01-01

Data sharing and mediation across disparate neuroimaging repositories requires extensive effort to ensure that the different domains of data types are referred to by commonly agreed upon terms. Within the SchizConnect project, which enables querying across decentralized databases of neuroimaging, clinical, and cognitive data from various studies of schizophrenia, we developed a model for each data domain, identified common usable terms that could be agreed upon across the repositories, and linked them to standard ontological terms where possible. We had the goal of facilitating both the current user experience in querying and future automated computations and reasoning regarding the data. We found that existing terminologies are incomplete for these purposes, even with the history of neuroimaging data sharing in the field; and we provide a model for efforts focused on querying multiple clinical neuroimaging repositories. PMID:26688838

Centralized mouse repositories.

PubMed

Donahue, Leah Rae; Hrabe de Angelis, Martin; Hagn, Michael; Franklin, Craig; Lloyd, K C Kent; Magnuson, Terry; McKerlie, Colin; Nakagata, Naomi; Obata, Yuichi; Read, Stuart; Wurst, Wolfgang; Hörlein, Andreas; Davisson, Muriel T

2012-10-01

Because the mouse is used so widely for biomedical research and the number of mouse models being generated is increasing rapidly, centralized repositories are essential if the valuable mouse strains and models that have been developed are to be securely preserved and fully exploited. Ensuring the ongoing availability of these mouse strains preserves the investment made in creating and characterizing them and creates a global resource of enormous value. The establishment of centralized mouse repositories around the world for distributing and archiving these resources has provided critical access to and preservation of these strains. This article describes the common and specialized activities provided by major mouse repositories around the world.

Virtual patient repositories--a comparative analysis.

PubMed

Küfner, Julia; Kononowicz, Andrzej A; Hege, Inga

2014-01-01

Virtual Patients (VPs) are an important component of medical education. One way to reduce the costs for creating VPs is sharing through repositories. We conducted a literature review to identify existing repositories and analyzed the 17 included repositories in regards to the search functions and metadata they provide. Most repositories provided some metadata such as title or description, whereas other data, such as educational objectives, were less frequent. Future research could, in cooperation with the repository provider, investigate user expectations and usage patterns.

Centralized Mouse Repositories

PubMed Central

Donahue, Leah Rae; de Angelis, Martin Hrabe; Hagn, Michael; Franklin, Craig; Lloyd, K. C. Kent; Magnuson, Terry; McKerlie, Colin; Nakagata, Naomi; Obata, Yuichi; Read, Stuart; Wurst, Wolfgang; Hörlein, Andreas; Davisson, Muriel T.

2013-01-01

Because the mouse is used so widely for biomedical research and the number of mouse models being generated is increasing rapidly, centralized repositories are essential if the valuable mouse strains and models that have been developed are to be securely preserved and fully exploited. Ensuring the ongoing availability of these mouse strains preserves the investment made in creating and characterizing them and creates a global resource of enormous value. The establishment of centralized mouse repositories around the world for distributing and archiving these resources has provided critical access to and preservation of these strains. This article describes the common and specialized activities provided by major mouse repositories around the world. PMID:22945696

Data Storing Proposal from Heterogeneous Systems into a Specialized Repository

NASA Astrophysics Data System (ADS)

Václavová, Andrea; Tanuška, Pavol; Jánošík, Ján

2016-12-01

The aim of this paper is to analyze and to propose an appropriate system for processing and simultaneously storing a vast volume of structured and unstructured data. The paper consists of three parts. The first part addresses the issue of structured and unstructured data. The second part provides the detailed analysis of data repositories and subsequent evaluation indicating which system would be for the given type and volume of data optimal. The third part focuses on the use of gathered information to transfer data to the proposed repository.

2012 best practices for repositories collection, storage, retrieval, and distribution of biological materials for research international society for biological and environmental repositories.

PubMed

2012-04-01

effective practices are presented for the management of specimen collections and repositories. The term "Best Practice" is used in cases where a level of operation is indicated that is above the basic recommended practice or more specifically designates the most effective practice. It is understood that repositories in certain locations or with particular financial constraints may not be able to adhere to each of the items designated as "Best Practices". Repositories fitting into either of these categories will need to decide how they might best adhere to these recommendations within their particular circumstances. While adherence to ISBER Best Practices is strictly on a voluntary basis, it is important to note that some aspects of specimen management are governed by national/federal, regional and local regulations. The reader should refer directly to regulations for their national/federal, regional and local requirements, as appropriate. ISBER has strived to include terminology appropriate to the various specimen types covered under these practices, but here too, the reader should take steps to ensure the appropriateness of the recommendations to their particular repository type prior to the implementation of any new approaches. Important terms within the document are italicized when first used in a section and defined in the glossary. The ISBER Best Practices are periodically reviewed and revised to reflect advances in research and technology. The third edition of the Best Practices builds on the foundation established in the first and second editions which were published in 2005 and 2008, respectively.

Desiderata for healthcare integrated data repositories based on architectural comparison of three public repositories.

PubMed

Huser, Vojtech; Cimino, James J

2013-01-01

Integrated data repositories (IDRs) are indispensable tools for numerous biomedical research studies. We compare three large IDRs (Informatics for Integrating Biology and the Bedside (i2b2), HMO Research Network's Virtual Data Warehouse (VDW) and Observational Medical Outcomes Partnership (OMOP) repository) in order to identify common architectural features that enable efficient storage and organization of large amounts of clinical data. We define three high-level classes of underlying data storage models and we analyze each repository using this classification. We look at how a set of sample facts is represented in each repository and conclude with a list of desiderata for IDRs that deal with the information storage model, terminology model, data integration and value-sets management.

10 CFR 960.3-1-4-2 - Site nomination for characterization.

Code of Federal Regulations, 2010 CFR

2010-01-01

... SITES FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-1-4-2 Site nomination for... types under expected repository conditions; evaluations of natural and man-made analogs of the repository and its subsystems, such as geothermally active areas, underground excavations, and case histories...

48 CFR 227.7207 - Contractor data repositories.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Computer Software and Computer Software Documentation 227.7207 Contractor data repositories. Follow 227.7108 when it is in the Government's interests to have a data repository include computer software or to have a separate computer software repository. Contractual instruments establishing the repository...

48 CFR 227.7207 - Contractor data repositories.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Computer Software and Computer Software Documentation 227.7207 Contractor data repositories. Follow 227.7108 when it is in the Government's interests to have a data repository include computer software or to have a separate computer software repository. Contractual instruments establishing the repository...

48 CFR 227.7207 - Contractor data repositories.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Computer Software and Computer Software Documentation 227.7207 Contractor data repositories. Follow 227.7108 when it is in the Government's interests to have a data repository include computer software or to have a separate computer software repository. Contractual instruments establishing the repository...

48 CFR 227.7207 - Contractor data repositories.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Computer Software and Computer Software Documentation 227.7207 Contractor data repositories. Follow 227.7108 when it is in the Government's interests to have a data repository include computer software or to have a separate computer software repository. Contractual instruments establishing the repository...

Classifying Clinical Trial Eligibility Criteria to Facilitate Phased Cohort Identification Using Clinical Data Repositories.

PubMed

Wang, Amy Y; Lancaster, William J; Wyatt, Matthew C; Rasmussen, Luke V; Fort, Daniel G; Cimino, James J

2017-01-01

A major challenge in using electronic health record repositories for research is the difficulty matching subject eligibility criteria to query capabilities of the repositories. We propose categories for study criteria corresponding to the effort needed for querying those criteria: "easy" (supporting automated queries), mixed (initial automated querying with manual review), "hard" (fully manual record review), and "impossible" or "point of enrollment" (not typically in health repositories). We obtained a sample of 292 criteria from 20 studies from ClinicalTrials.gov. Six independent reviewers, three each from two academic research institutions, rated criteria according to our four types. We observed high interrater reliability both within and between institutions. The analysis demonstrated typical features of criteria that map with varying levels of difficulty to repositories. We propose using these features to improve enrollment workflow through more standardized study criteria, self-service repository queries, and analyst-mediated retrievals.

Classifying Clinical Trial Eligibility Criteria to Facilitate Phased Cohort Identification Using Clinical Data Repositories

PubMed Central

Wang, Amy Y.; Lancaster, William J.; Wyatt, Matthew C.; Rasmussen, Luke V.; Fort, Daniel G.; Cimino, James J.

2017-01-01

A major challenge in using electronic health record repositories for research is the difficulty matching subject eligibility criteria to query capabilities of the repositories. We propose categories for study criteria corresponding to the effort needed for querying those criteria: “easy” (supporting automated queries), mixed (initial automated querying with manual review), “hard” (fully manual record review), and “impossible” or “point of enrollment” (not typically in health repositories). We obtained a sample of 292 criteria from 20 studies from ClinicalTrials.gov. Six independent reviewers, three each from two academic research institutions, rated criteria according to our four types. We observed high interrater reliability both within and between institutions. The analysis demonstrated typical features of criteria that map with varying levels of difficulty to repositories. We propose using these features to improve enrollment workflow through more standardized study criteria, self-service repository queries, and analyst-mediated retrievals. PMID:29854246

Thermal Analysis of a Nuclear Waste Repository in Argillite Host Rock

NASA Astrophysics Data System (ADS)

Hadgu, T.; Gomez, S. P.; Matteo, E. N.

2017-12-01

Disposal of high-level nuclear waste in a geological repository requires analysis of heat distribution as a result of decay heat. Such an analysis supports design of repository layout to define repository footprint as well as provide information of importance to overall design. The analysis is also used in the study of potential migration of radionuclides to the accessible environment. In this study, thermal analysis for high-level waste and spent nuclear fuel in a generic repository in argillite host rock is presented. The thermal analysis utilized both semi-analytical and numerical modeling in the near field of a repository. The semi-analytical method looks at heat transport by conduction in the repository and surroundings. The results of the simulation method are temperature histories at selected radial distances from the waste package. A 3-D thermal-hydrologic numerical model was also conducted to study fluid and heat distribution in the near field. The thermal analysis assumed a generic geological repository at 500 m depth. For the semi-analytical method, a backfilled closed repository was assumed with basic design and material properties. For the thermal-hydrologic numerical method, a repository layout with disposal in horizontal boreholes was assumed. The 3-D modeling domain covers a limited portion of the repository footprint to enable a detailed thermal analysis. A highly refined unstructured mesh was used with increased discretization near heat sources and at intersections of different materials. All simulations considered different parameter values for properties of components of the engineered barrier system (i.e. buffer, disturbed rock zone and the host rock), and different surface storage times. Results of the different modeling cases are presented and include temperature and fluid flow profiles in the near field at different simulation times. Sandia National Laboratories is a multimission laboratory managed and operated by National Technology and

48 CFR 227.7108 - Contractor data repositories.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Technical Data 227.7108 Contractor data repositories. (a) Contractor data repositories may be established... procedures for protecting technical data delivered to or stored at the repository from unauthorized release... disclosure of technical data from the repository to third parties consistent with the Government's rights in...

Desiderata for Healthcare Integrated Data Repositories Based on Architectural Comparison of Three Public Repositories

PubMed Central

Huser, Vojtech; Cimino, James J.

2013-01-01

Integrated data repositories (IDRs) are indispensable tools for numerous biomedical research studies. We compare three large IDRs (Informatics for Integrating Biology and the Bedside (i2b2), HMO Research Network’s Virtual Data Warehouse (VDW) and Observational Medical Outcomes Partnership (OMOP) repository) in order to identify common architectural features that enable efficient storage and organization of large amounts of clinical data. We define three high-level classes of underlying data storage models and we analyze each repository using this classification. We look at how a set of sample facts is represented in each repository and conclude with a list of desiderata for IDRs that deal with the information storage model, terminology model, data integration and value-sets management. PMID:24551366

Influence analysis of Github repositories.

PubMed

Hu, Yan; Zhang, Jun; Bai, Xiaomei; Yu, Shuo; Yang, Zhuo

2016-01-01

With the support of cloud computing techniques, social coding platforms have changed the style of software development. Github is now the most popular social coding platform and project hosting service. Software developers of various levels keep entering Github, and use Github to save their public and private software projects. The large amounts of software developers and software repositories on Github are posing new challenges to the world of software engineering. This paper tries to tackle one of the important problems: analyzing the importance and influence of Github repositories. We proposed a HITS based influence analysis on graphs that represent the star relationship between Github users and repositories. A weighted version of HITS is applied to the overall star graph, and generates a different set of top influential repositories other than the results from standard version of HITS algorithm. We also conduct the influential analysis on per-month star graph, and study the monthly influence ranking of top repositories.

Biological Web Service Repositories Review

PubMed Central

Urdidiales‐Nieto, David; Navas‐Delgado, Ismael

2016-01-01

Abstract Web services play a key role in bioinformatics enabling the integration of database access and analysis of algorithms. However, Web service repositories do not usually publish information on the changes made to their registered Web services. Dynamism is directly related to the changes in the repositories (services registered or unregistered) and at service level (annotation changes). Thus, users, software clients or workflow based approaches lack enough relevant information to decide when they should review or re‐execute a Web service or workflow to get updated or improved results. The dynamism of the repository could be a measure for workflow developers to re‐check service availability and annotation changes in the services of interest to them. This paper presents a review on the most well‐known Web service repositories in the life sciences including an analysis of their dynamism. Freshness is introduced in this paper, and has been used as the measure for the dynamism of these repositories. PMID:27783459

Repository Profiles for Atmospheric and Climate Sciences: Capabilities and Trends in Data Services

NASA Astrophysics Data System (ADS)

Hou, C. Y.; Thompson, C. A.; Palmer, C. L.

2014-12-01

As digital research data proliferate and expectations for open access escalate, the landscape of data repositories is becoming more complex. For example, DataBib currently identifies 980 data repositories across the disciplines, with 117 categorized under Geosciences. In atmospheric and climate sciences, there are great expectations for the integration and reuse of data for advancing science. To realize this potential, resources are needed that explicate the range of repository options available for locating and depositing open data, their conditions of access and use, and the services and tools they provide. This study profiled 38 open digital repositories in the atmospheric and climate sciences, analyzing each on 55 criteria through content analysis of their websites. The results provide a systematic way to assess and compare capabilities, services, and institutional characteristics and identify trends across repositories. Selected results from the more detailed outcomes to be presented: Most repositories offer guidance on data format(s) for submission and dissemination. 42% offer authorization-free access. More than half use some type of data identification system such as DOIs. Nearly half offer some data processing, with a similar number providing software or tools. 78.9% request that users cite or acknowledge datasets used and the data center. Only 21.1% recommend specific metadata standards, such as ISO 19115 or Dublin Core, with more than half utilizing a customized metadata scheme. Information was rarely provided on repository certification and accreditation and uneven for transfer of rights and data security. Few provided policy information on preservation, migration, reappraisal, disposal, or long-term sustainability. As repository use increases, it will be important for institutions to make their procedures and policies explicit, to build trust with user communities and improve efficiencies in data sharing. Resources such as repository profiles will be

Biological Web Service Repositories Review.

PubMed

Urdidiales-Nieto, David; Navas-Delgado, Ismael; Aldana-Montes, José F

2017-05-01

Web services play a key role in bioinformatics enabling the integration of database access and analysis of algorithms. However, Web service repositories do not usually publish information on the changes made to their registered Web services. Dynamism is directly related to the changes in the repositories (services registered or unregistered) and at service level (annotation changes). Thus, users, software clients or workflow based approaches lack enough relevant information to decide when they should review or re-execute a Web service or workflow to get updated or improved results. The dynamism of the repository could be a measure for workflow developers to re-check service availability and annotation changes in the services of interest to them. This paper presents a review on the most well-known Web service repositories in the life sciences including an analysis of their dynamism. Freshness is introduced in this paper, and has been used as the measure for the dynamism of these repositories. © 2017 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA.

Projected environmental impacts of radioactive material transportation to the first US repository site

DOE Office of Scientific and Technical Information (OSTI.GOV)

Neuhauser, K.S.; Cashwell, J.W.; Reardon, P.C.

1986-12-31

This paper discusses the relative national environmental impacts of transporting nuclear wastes to each of the nine candidate repository sites in the United States. Several of the potential sites are closely clustered and, for the purpose of distance and routing calculations, are treated as a single location. These are: Cypress Creek Dome and Richton Dome in Mississippi (Gulf Interior Region), Deaf Smith County and Swisher County sites in Texas (Permian Basin), and Davis Canyon and Lavender Canyon site in Utah (Paradox Basin). The remaining sites are: Vacherie Dome, Louisiana; Yucca Mountain, Nevada; and Hanford Reservation, Washington. For compatibility with bothmore » the repository system authorized by the NWPA and with the MRS option, two separate scenarios were analyzed. In belief, they are (1) shipment of spent fuel and high-level wastes (HLW) directly from waste generators to a repository (Reference Case) and (2) shipment of spent fuel to a Monitored Retrievable Storage (MRS) facility and then to a repository. Between 17 and 38 truck accident fatalities, between 1.4 and 7.7 rail accident fatalities, and between 0.22 and 12 radiological health effects can be expected to occur as a result of radioactive material transportation during the 26-year operating period of the first repository. During the same period in the United States, about 65,000 total deaths from truck accidents and about 32,000 total deaths from rail accidents would occur; also an estimated 58,300 cancer fatalities are predicted to occur in the United States during a 26-year period from exposure to background radiation alone (not including medical and other manmade sources). The risks reported here are upper limits and are small by comparison with the "natural background" of risks of the same type. 3 refs., 6 tabs.« less

Preservation of Earth Science Data History with Digital Content Repository Technology

NASA Astrophysics Data System (ADS)

Wei, Y.; Pan, J.; Shrestha, B.; Cook, R. B.

2011-12-01

An increasing need for derived and on-demand data product in Earth Science research makes the digital content more difficult for providers to manage and preserve and for users to locate, understand, and consume. Specifically, this increasing need presents additional challenges in managing data processing history information and delivering such information to end users. For example, the North American Carbon Program (NACP) Multi-scale Synthesis and Terrestrial Model Intercomparison Project (MsTMIP) chose a modified SYNMAP land cover data as one of the input driver data for participating terrestrial biospheric models. The global 1km resolution SYNMAP data was created by harmonizing 3 remote sensing-based land cover products: GLCC, GLC2000, and the MODIS land cover product. The original SYNMAP land cover data was aggregated into half and quarter degree resolution. It was then enhanced with more detailed grassland and cropland types. Currently, there lacks an effective mechanism to convey this data processing information to different modeling teams for them to determine if a data product meets their needs. It still highly relies on offline human interaction. The NASA-sponsored ORNL DAAC has leveraged the contemporary digital object repository technology to promote the representation, management, and delivery of data processing history and provenance information. Within digital object repository, different data products are managed as objects, with metadata as attributes and content delivery and management services as dissemination methods. Derivation relationships among data products can be semantically referenced between digital objects. Within the repository, data users can easily track a derived data product back to its origin, explorer metadata and documents about each intermediate data product, and discover processing details involved in each derivation step. Coupled with Drupal Web Content Management System, the digital repository interface was enhanced to

Revision history aware repositories of computational models of biological systems.

PubMed

Miller, Andrew K; Yu, Tommy; Britten, Randall; Cooling, Mike T; Lawson, James; Cowan, Dougal; Garny, Alan; Halstead, Matt D B; Hunter, Peter J; Nickerson, David P; Nunns, Geo; Wimalaratne, Sarala M; Nielsen, Poul M F

2011-01-14

Building repositories of computational models of biological systems ensures that published models are available for both education and further research, and can provide a source of smaller, previously verified models to integrate into a larger model. One problem with earlier repositories has been the limitations in facilities to record the revision history of models. Often, these facilities are limited to a linear series of versions which were deposited in the repository. This is problematic for several reasons. Firstly, there are many instances in the history of biological systems modelling where an 'ancestral' model is modified by different groups to create many different models. With a linear series of versions, if the changes made to one model are merged into another model, the merge appears as a single item in the history. This hides useful revision history information, and also makes further merges much more difficult, as there is no record of which changes have or have not already been merged. In addition, a long series of individual changes made outside of the repository are also all merged into a single revision when they are put back into the repository, making it difficult to separate out individual changes. Furthermore, many earlier repositories only retain the revision history of individual files, rather than of a group of files. This is an important limitation to overcome, because some types of models, such as CellML 1.1 models, can be developed as a collection of modules, each in a separate file. The need for revision history is widely recognised for computer software, and a lot of work has gone into developing version control systems and distributed version control systems (DVCSs) for tracking the revision history. However, to date, there has been no published research on how DVCSs can be applied to repositories of computational models of biological systems. We have extended the Physiome Model Repository software to be fully revision history aware

17 CFR 45.10 - Reporting to a single swap data repository.

Code of Federal Regulations, 2012 CFR

2012-04-01

... the swap data repository to which the first report of required swap creation data is made pursuant to... designated contract market that reports required swap creation data as required by § 45.3 shall report all... of the swap data repository to which required swap creation data is reported by the swap execution...

17 CFR 45.10 - Reporting to a single swap data repository.

Code of Federal Regulations, 2013 CFR

2013-04-01

... the swap data repository to which the first report of required swap creation data is made pursuant to... designated contract market that reports required swap creation data as required by § 45.3 shall report all... of the swap data repository to which required swap creation data is reported by the swap execution...

SemanticOrganizer: A Customizable Semantic Repository for Distributed NASA Project Teams

NASA Technical Reports Server (NTRS)

Keller, Richard M.; Berrios, Daniel C.; Carvalho, Robert E.; Hall, David R.; Rich, Stephen J.; Sturken, Ian B.; Swanson, Keith J.; Wolfe, Shawn R.

2004-01-01

SemanticOrganizer is a collaborative knowledge management system designed to support distributed NASA projects, including diverse teams of scientists, engineers, and accident investigators. The system provides a customizable, semantically structured information repository that stores work products relevant to multiple projects of differing types. SemanticOrganizer is one of the earliest and largest semantic web applications deployed at NASA to date, and has been used in diverse contexts ranging from the investigation of Space Shuttle Columbia's accident to the search for life on other planets. Although the underlying repository employs a single unified ontology, access control and ontology customization mechanisms make the repository contents appear different for each project team. This paper describes SemanticOrganizer, its customization facilities, and a sampling of its applications. The paper also summarizes some key lessons learned from building and fielding a successful semantic web application across a wide-ranging set of domains with diverse users.

17 CFR 45.10 - Reporting to a single swap data repository.

Code of Federal Regulations, 2014 CFR

2014-04-01

..., which shall be the swap data repository to which the first report of required swap creation data is made... designated contract market that reports required swap creation data as required by § 45.3 shall report all... of the swap data repository to which required swap creation data is reported by the swap execution...

Integrating repositories with fuel cycles: The airport authority model

DOE Office of Scientific and Technical Information (OSTI.GOV)

Forsberg, C.

2012-07-01

members appointed by the state governor, county governments, and city governments. This structure (1) enables state and local governments to work together to maximize job and tax benefits to local communities and the state, (2) provides a mechanism to address local concerns such as airport noise, and (3) creates an institutional structure with large incentives to maximize the value of the common asset, the runway. A repository site authority would have a similar structure and be the local interface to any national waste management authority. (authors)« less

48 CFR 227.7207 - Contractor data repositories.

Code of Federal Regulations, 2010 CFR

2010-10-01

... repositories. 227.7207 Section 227.7207 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS... Computer Software and Computer Software Documentation 227.7207 Contractor data repositories. Follow 227.7108 when it is in the Government's interests to have a data repository include computer software or to...

21 CFR 522.480 - Repository corticotropin injection.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Repository corticotropin injection. 522.480 Section 522.480 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... § 522.480 Repository corticotropin injection. (a)(1) Specifications. The drug conforms to repository...

[Self-archiving of biomedical papers in open access repositories].

PubMed

Abad-García, M Francisca; Melero, Remedios; Abadal, Ernest; González-Teruel, Aurora

2010-04-01

Open-access literature is digital, online, free of charge, and free of most copyright and licensing restrictions. Self-archiving or deposit of scholarly outputs in institutional repositories (open-access green route) is increasingly present in the activities of the scientific community. Besides the benefits of open access for visibility and dissemination of science, it is increasingly more often required by funding agencies to deposit papers and any other type of documents in repositories. In the biomedical environment this is even more relevant by the impact scientific literature can have on public health. However, to make self-archiving feasible, authors should be aware of its meaning and the terms in which they are allowed to archive their works. In that sense, there are some tools like Sherpa/RoMEO or DULCINEA (both directories of copyright licences of scientific journals at different levels) to find out what rights are retained by authors when they publish a paper and if they allow to implement self-archiving. PubMed Central and its British and Canadian counterparts are the main thematic repositories for biomedical fields. In our country there is none of similar nature, but most of the universities and CSIC, have already created their own institutional repositories. The increase in visibility of research results and their impact on a greater and earlier citation is one of the most frequently advance of open access, but removal of economic barriers to access to information is also a benefit to break borders between groups.

[Tissue repositories for research at Sheba Medical Center(SMC].

PubMed

Cohen, Yehudit; Barshack, Iris; Onn, Amir

2013-06-01

Cancer is the number one cause of death in both genders. Breakthroughs in the understanding of cancer biology, the identification of prognostic factors, and the development of new treatments are increasingly dependent on access to human cancer tissues with linked clinicopathological data. Access to human tumor samples and a large investment in translational research are needed to advance this research. The SMC tissue repositories provide researchers with biological materials, which are essential tools for cancer research. SMC tissue repositories for research aim to collect, document and preserve human biospecimens from patients with cancerous diseases. This is in order to provide the highest quality and well annotated biological biospecimens, used as essential tools to achieve the growing demands of scientific research needs. Such repositories are partners in acceLerating biomedical research and medical product development through clinical resources, in order to apply best options to the patients. Following Institutional Review Board approval and signing an Informed Consent Form, the tumor and tumor-free specimens are coLLected by a designated pathologist at the operating room only when there is a sufficient amount of the tumor, in excess of the routine needs. Blood samples are collected prior to the procedure. Other types of specimens collected include ascites fluid, pleural effusion, tissues for Optimal Cutting Temperature [OCT] and primary culture etc. Demographic, clinical, pathologicaL, and follow-up data are collected in a designated database. SMC has already established several organ or disease-specific tissue repositories within different departments. The foundation of tissue repositories requires the concentrated effort of a multidisciplinary team composed of paramedical, medical and scientific professionals. Research projects using these specimens facilitate the development of 'targeted therapy', accelerate basic research aimed at clarifying molecular

Supporting multiple domains in a single reuse repository

NASA Technical Reports Server (NTRS)

Eichmann, David A.

1992-01-01

Domain analysis typically results in the construction of a domain-specific repository. Such a repository imposes artificial boundaries on the sharing of similar assets between related domains. A lattice-based approach to repository modeling can preserve a reuser's domain specific view of the repository, while avoiding replication of commonly used assets and supporting a more general perspective on domain interrelationships.

US/German Collaboration in Salt Repository Research, Design and Operation - 13243

DOE Office of Scientific and Technical Information (OSTI.GOV)

Steininger, Walter; Hansen, Frank; Biurrun, Enrique

2013-07-01

Recent developments in the US and Germany [1-3] have precipitated renewed efforts in salt repository investigations and related studies. Both the German rock salt repository activities and the US waste management programs currently face challenges that may adversely affect their respective current and future state-of-the-art core capabilities in rock salt repository science and technology. The research agenda being pursued by our respective countries leverages collective efforts for the benefit of both programs. The topics addressed by the US/German salt repository collaborations align well with the findings and recommendations summarized in the January 2012 US Blue Ribbon Commission on America's Nuclearmore » Future (BRC) report [4] and are consistent with the aspirations of the key topics of the Strategic Research Agenda of the Implementing Geological Disposal of Radioactive Waste Technology Platform (IGD-TP) [5]. Against this background, a revival of joint efforts in salt repository investigations after some years of hibernation has been undertaken to leverage collective efforts in salt repository research, design, operations, and related issues for the benefit of respective programs and to form a basis for providing an attractive, cost-effective insurance against the premature loss of virtually irreplaceable scientific expertise and institutional memory. (authors)« less

jPOSTrepo: an international standard data repository for proteomes

PubMed Central

Okuda, Shujiro; Watanabe, Yu; Moriya, Yuki; Kawano, Shin; Yamamoto, Tadashi; Matsumoto, Masaki; Takami, Tomoyo; Kobayashi, Daiki; Araki, Norie; Yoshizawa, Akiyasu C.; Tabata, Tsuyoshi; Sugiyama, Naoyuki; Goto, Susumu; Ishihama, Yasushi

2017-01-01

Major advancements have recently been made in mass spectrometry-based proteomics, yielding an increasing number of datasets from various proteomics projects worldwide. In order to facilitate the sharing and reuse of promising datasets, it is important to construct appropriate, high-quality public data repositories. jPOSTrepo (https://repository.jpostdb.org/) has successfully implemented several unique features, including high-speed file uploading, flexible file management and easy-to-use interfaces. This repository has been launched as a public repository containing various proteomic datasets and is available for researchers worldwide. In addition, our repository has joined the ProteomeXchange consortium, which includes the most popular public repositories such as PRIDE in Europe for MS/MS datasets and PASSEL for SRM datasets in the USA. Later MassIVE was introduced in the USA and accepted into the ProteomeXchange, as was our repository in July 2016, providing important datasets from Asia/Oceania. Accordingly, this repository thus contributes to a global alliance to share and store all datasets from a wide variety of proteomics experiments. Thus, the repository is expected to become a major repository, particularly for data collected in the Asia/Oceania region. PMID:27899654

Implementation of the Brazilian National Repository - RBMN Project - 13008

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cassia Oliveira de Tello, Cledola

2013-07-01

Ionizing radiation in Brazil is used in electricity generation, medicine, industry, agriculture and for research and development purposes. All these activities can generate radioactive waste. At this point, in Brazil, the use of nuclear energy and radioisotopes justifies the construction of a national repository for radioactive wastes of low and intermediate-level. According to Federal Law No. 10308, Brazilian National Commission for Nuclear Energy (CNEN) is responsible for designing and constructing the intermediate and final storages for radioactive wastes. Additionally, a restriction on the construction of Angra 3 is that the repository is under construction until its operation start, attaining somemore » requirements of the Brazilian Environmental Regulator (IBAMA). Besides this NPP, in the National Energy Program is previewed the installation of four more plants, by 2030. In November 2008, CNEN launched the Project RBMN (Repository for Low and Intermediate-Level Radioactive Wastes), which aims at the implantation of a National Repository for disposal of low and intermediate-level of radiation wastes. This Project has some aspects that are unique in the Brazilian context, especially referring to the time between its construction and the end of its institutional period. This time is about 360 years, when the area will be released for unrestricted uses. It means that the Repository must be safe and secure for more than three hundred years, which is longer than half of the whole of Brazilian history. This aspect is very new for the Brazilian people, bringing a new dimension to public acceptance. Another point is this will be the first repository in South America, bringing a real challenge for the continent. The current status of the Project is summarized. (authors)« less

17 CFR 49.12 - Swap data repository recordkeeping requirements.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 17 Commodity and Securities Exchanges 1 2012-04-01 2012-04-01 false Swap data repository... COMMISSION SWAP DATA REPOSITORIES § 49.12 Swap data repository recordkeeping requirements. (a) A registered swap data repository shall maintain its books and records in accordance with the requirements of part...

17 CFR 49.12 - Swap data repository recordkeeping requirements.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 17 Commodity and Securities Exchanges 1 2013-04-01 2013-04-01 false Swap data repository... COMMISSION SWAP DATA REPOSITORIES § 49.12 Swap data repository recordkeeping requirements. (a) A registered swap data repository shall maintain its books and records in accordance with the requirements of part...

17 CFR 49.12 - Swap data repository recordkeeping requirements.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 17 Commodity and Securities Exchanges 2 2014-04-01 2014-04-01 false Swap data repository... COMMISSION (CONTINUED) SWAP DATA REPOSITORIES § 49.12 Swap data repository recordkeeping requirements. (a) A registered swap data repository shall maintain its books and records in accordance with the requirements of...

48 CFR 227.7108 - Contractor data repositories.

Code of Federal Regulations, 2014 CFR

2014-10-01

... repositories. 227.7108 Section 227.7108 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in... such data; (3) When required by the contracting officer, deliver data to the Government on paper or in...

48 CFR 227.7108 - Contractor data repositories.

Code of Federal Regulations, 2013 CFR

2013-10-01

... repositories. 227.7108 Section 227.7108 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in... such data; (3) When required by the contracting officer, deliver data to the Government on paper or in...

48 CFR 227.7108 - Contractor data repositories.

Code of Federal Regulations, 2011 CFR

2011-10-01

... repositories. 227.7108 Section 227.7108 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in... such data; (3) When required by the contracting officer, deliver data to the Government on paper or in...

48 CFR 227.7108 - Contractor data repositories.

Code of Federal Regulations, 2012 CFR

2012-10-01

... repositories. 227.7108 Section 227.7108 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in... such data; (3) When required by the contracting officer, deliver data to the Government on paper or in...

Building Scientific Data's list of recommended data repositories

NASA Astrophysics Data System (ADS)

Hufton, A. L.; Khodiyar, V.; Hrynaszkiewicz, I.

2016-12-01

When Scientific Data launched in 2014 we provided our authors with a list of recommended data repositories to help them identify data hosting options that were likely to meet the journal's requirements. This list has grown in size and scope, and is now a central resource for authors across the Nature-titled journals. It has also been used in the development of data deposition policies and recommended repository lists across Springer Nature and at other publishers. Each new addition to the list is assessed according to a series of criteria that emphasize the stability of the resource, its commitment to principles of open science and its implementation of relevant community standards and reporting guidelines. A preference is expressed for repositories that issue digital object identifiers (DOIs) through the DataCite system and that share data under the Creative Commons CC0 waiver. Scientific Data currently lists fourteen repositories that focus on specific areas within the Earth and environmental sciences, as well as the broad scope repositories, Dryad and figshare. Readers can browse and filter datasets published at the journal by the host repository using ISA-explorer, a demo tool built by the ISA-tools team at Oxford University1. We believe that well-maintained lists like this one help publishers build a network of trust with community data repositories and provide an important complement to more comprehensive data repository indices and more formal certification efforts. In parallel, Scientific Data has also improved its policies to better support submissions from authors using institutional and project-specific repositories, without requiring each to apply for listing individually. Online resources Journal homepage: http://www.nature.com/scientificdata Data repository criteria: http://www.nature.com/sdata/policies/data-policies#repo-criteria Recommended data repositories: http://www.nature.com/sdata/policies/repositories Archived copies of the list: https

A scoping review of online repositories of quality improvement projects, interventions and initiatives in healthcare.

PubMed

Bytautas, Jessica P; Gheihman, Galina; Dobrow, Mark J

2017-04-01

Quality improvement (QI) is becoming an important focal point for health systems. There is increasing interest among health system stakeholders to learn from and share experiences on the use of QI methods and approaches in their work. Yet there are few easily accessible, online repositories dedicated to documenting QI activity. We conducted a scoping review of publicly available, web-based QI repositories to (i) identify current approaches to sharing information on QI practices; (ii) categorise these approaches based on hosting, scope and size, content acquisition and eligibility, content format and search, and evaluation and engagement characteristics; and (iii) review evaluations of the design, usefulness and impact of their online QI practice repositories. The search strategy consisted of traditional database and grey literature searches, as well as expert consultation, with the ultimate aim of identifying and describing QI repositories of practices undertaken in a healthcare context. We identified 13 QI repositories and found substantial variation across the five categories. The QI repositories used different terminology (eg, practices vs case studies) and approaches to content acquisition, and varied in terms of primary areas of focus. All provided some means for organising content according to categories or themes and most provided at least rudimentary keyword search functionality. Notably, none of the QI repositories included evaluations of their impact. With growing interest in sharing and spreading best practices and increasing reliance on QI as a key contributor to health system performance, the role of QI repositories is likely to expand. Designing future QI repositories based on knowledge of the range and type of features available is an important starting point for improving their usefulness and impact. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

10 CFR 960.3-1-3 - Regionality.

Code of Federal Regulations, 2010 CFR

2010-01-01

... REPOSITORY Implementation Guidelines § 960.3-1-3 Regionality. In making site recommendations for repository development after the site for the first repository has been recommended, the Secretary shall give due... repositories. Such consideration shall take into account the proximity of sites to locations at which waste is...

NASA Biological Specimen Repository

NASA Technical Reports Server (NTRS)

McMonigal, K. A.; Pietrzyk, R. A.; Sams, C. F.; Johnson, M. A.

2010-01-01

The NASA Biological Specimen Repository (NBSR) was established in 2006 to collect, process, preserve and distribute spaceflight-related biological specimens from long duration ISS astronauts. This repository provides unique opportunities to study longitudinal changes in human physiology spanning may missions. The NBSR collects blood and urine samples from all participating ISS crewmembers who have provided informed consent. These biological samples are collected once before flight, during flight scheduled on flight days 15, 30, 60, 120 and within 2 weeks of landing. Postflight sessions are conducted 3 and 30 days after landing. The number of in-flight sessions is dependent on the duration of the mission. Specimens are maintained under optimal storage conditions in a manner that will maximize their integrity and viability for future research The repository operates under the authority of the NASA/JSC Committee for the Protection of Human Subjects to support scientific discovery that contributes to our fundamental knowledge in the area of human physiological changes and adaptation to a microgravity environment. The NBSR will institute guidelines for the solicitation, review and sample distribution process through establishment of the NBSR Advisory Board. The Advisory Board will be composed of representatives of all participating space agencies to evaluate each request from investigators for use of the samples. This process will be consistent with ethical principles, protection of crewmember confidentiality, prevailing laws and regulations, intellectual property policies, and consent form language. Operations supporting the NBSR are scheduled to continue until the end of U.S. presence on the ISS. Sample distribution is proposed to begin with selections on investigations beginning in 2017. The availability of the NBSR will contribute to the body of knowledge about the diverse factors of spaceflight on human physiology.

Data repositories for medical education research: issues and recommendations.

PubMed

Schwartz, Alan; Pappas, Cleo; Sandlow, Leslie J

2010-05-01

The authors explore issues surrounding digital repositories with the twofold intention of clarifying their creation, structure, content, and use, and considering the implementation of a global digital repository for medical education research data sets-an online site where medical education researchers would be encouraged to deposit their data in order to facilitate the reuse and reanalysis of the data by other researchers. By motivating data sharing and reuse, investigators, medical schools, and other stakeholders might see substantial benefits to their own endeavors and to the progress of the field of medical education.The authors review digital repositories in medicine, social sciences, and education, describe the contents and scope of repositories, and present extant examples. The authors describe the potential benefits of a medical education data repository and report results of a survey of the Society for Directors of Research in Medicine Education, in which participants responded to questions about data sharing and a potential data repository. Respondents strongly endorsed data sharing, with the caveat that principal investigators should choose whether or not to share data they collect. A large majority believed that a repository would benefit their unit and the field of medical education. Few reported using existing repositories. Finally, the authors consider challenges to the establishment of such a repository, including taxonomic organization, intellectual property concerns, human subjects protection, technological infrastructure, and evaluation standards. The authors conclude with recommendations for how a medical education data repository could be successfully developed.

Data Publishing and Sharing Via the THREDDS Data Repository

NASA Astrophysics Data System (ADS)

Wilson, A.; Caron, J.; Davis, E.; Baltzer, T.

2007-12-01

The terms "Team Science" and "Networked Science" have been coined to describe a virtual organization of researchers tied via some intellectual challenge, but often located in different organizations and locations. A critical component to these endeavors is publishing and sharing of content, including scientific data. Imagine pointing your web browser to a web page that interactively lets you upload data and metadata to a repository residing on a remote server, which can then be accessed by others in a secure fasion via the web. While any content can be added to this repository, it is designed particularly for storing and sharing scientific data and metadata. Server support includes uploading of data files that can subsequently be subsetted, aggregrated, and served in NetCDF or other scientific data formats. Metadata can be associated with the data and interactively edited. The THREDDS Data Repository (TDR) is a server that provides client initiated, on demand, location transparent storage for data of any type that can then be served by the THREDDS Data Server (TDS). The TDR provides functionality to: * securely store and "own" data files and associated metadata * upload files via HTTP and gridftp * upload a collection of data as single file * modify and restructure repository contents * incorporate metadata provided by the user * generate additional metadata programmatically * edit individual metadata elements The TDR can exist separately from a TDS, serving content via HTTP. Also, it can work in conjunction with the TDS, which includes functionality to provide: * access to data in a variety of formats via -- OPeNDAP -- OGC Web Coverage Service (for gridded datasets) -- bulk HTTP file transfer * a NetCDF view of datasets in NetCDF, OPeNDAP, HDF-5, GRIB, and NEXRAD formats * serving of very large volume datasets, such as NEXRAD radar * aggregation into virtual datasets * subsetting via OPeNDAP and NetCDF Subsetting services This talk will discuss TDR

Large-Scale In-situ Experiments to Determine Geochemical Alterations and Microbial Activities at the Geological Repository

NASA Astrophysics Data System (ADS)

Choung, S.; Francis, A. J.; Um, W.; Choi, S.; Kim, S.; Park, J.; Kim, S.

2013-12-01

The countries that have generated nuclear power have facing problems on the disposal of accumulated radioactive wastes. Geological disposal method has been chosen in many countries including Korea. A safety issue after the closure of geological repository has been raised, because microbial activities lead overpressure in the underground facilities through gas production. In particular, biodegradable organic materials derived from low- and intermediate-level radioactive wastes play important role on microbial activities in the geological repository. This study performed large scale in-situ experiments using organic wastes and groundwater, and investigated geochemical alteration and microbial activities at early stage (~63 days) as representative of the period, after closure of the geological repository. The geochemical alteration controlled significantly the microorganism types and populations. Database of the biogeochemical alteration facilitates prediction of radionuclides' mobility and establishment of remedial strategy against unpredictable accidents and hazards at early stage right after closure of the geological repository.

Institutional Repositories as Infrastructures for Long-Term Preservation

ERIC Educational Resources Information Center

Francke, Helena; Gamalielsson, Jonas; Lundell, Björn

2017-01-01

Introduction: The study describes the conditions for long-term preservation of the content of the institutional repositories of Swedish higher education institutions based on an investigation of how deposited files are managed with regards to file format and how representatives of the repositories describe the functions of the repositories.…

Collaborative Information Retrieval Method among Personal Repositories

NASA Astrophysics Data System (ADS)

Kamei, Koji; Yukawa, Takashi; Yoshida, Sen; Kuwabara, Kazuhiro

In this paper, we describe a collaborative information retrieval method among personal repositorie and an implementation of the method on a personal agent framework. We propose a framework for personal agents that aims to enable the sharing and exchange of information resources that are distributed unevenly among individuals. The kernel of a personal agent framework is an RDF(resource description framework)-based information repository for storing, retrieving and manipulating privately collected information, such as documents the user read and/or wrote, email he/she exchanged, web pages he/she browsed, etc. The repository also collects annotations to information resources that describe relationships among information resources and records of interaction between the user and information resources. Since the information resources in a personal repository and their structure are personalized, information retrieval from other users' is an important application of the personal agent. A vector space model with a personalized concept-base is employed as an information retrieval mechanism in a personal repository. Since a personalized concept-base is constructed from information resources in a personal repository, it reflects its user's knowledge and interests. On the other hand, it leads to another problem while querying other users' personal repositories; that is, simply transferring query requests does not provide desirable results. To solve this problem, we propose a query equalization scheme based on a relevance feedback method for collaborative information retrieval between personalized concept-bases. In this paper, we describe an implementation of the collaborative information retrieval method and its user interface on the personal agent framework.

Food entries in a large allergy data repository

PubMed Central

Plasek, Joseph M.; Goss, Foster R.; Lai, Kenneth H.; Lau, Jason J.; Seger,, Diane L.; Blumenthal, Kimberly G.; Wickner, Paige G.; Slight, Sarah P.; Chang, Frank Y.; Topaz, Maxim; Bates, David W.

2016-01-01

Objective Accurate food adverse sensitivity documentation in electronic health records (EHRs) is crucial to patient safety. This study examined, encoded, and grouped foods that caused any adverse sensitivity in a large allergy repository using natural language processing and standard terminologies. Methods Using the Medical Text Extraction, Reasoning, and Mapping System (MTERMS), we processed both structured and free-text entries stored in an enterprise-wide allergy repository (Partners’ Enterprise-wide Allergy Repository), normalized diverse food allergen terms into concepts, and encoded these concepts using the Systematized Nomenclature of Medicine – Clinical Terms (SNOMED-CT) and Unique Ingredient Identifiers (UNII) terminologies. Concept coverage also was assessed for these two terminologies. We further categorized allergen concepts into groups and calculated the frequencies of these concepts by group. Finally, we conducted an external validation of MTERMS’s performance when identifying food allergen terms, using a randomized sample from a different institution. Results We identified 158 552 food allergen records (2140 unique terms) in the Partners repository, corresponding to 672 food allergen concepts. High-frequency groups included shellfish (19.3%), fruits or vegetables (18.4%), dairy (9.0%), peanuts (8.5%), tree nuts (8.5%), eggs (6.0%), grains (5.1%), and additives (4.7%). Ambiguous, generic concepts such as “nuts” and “seafood” accounted for 8.8% of the records. SNOMED-CT covered more concepts than UNII in terms of exact (81.7% vs 68.0%) and partial (14.3% vs 9.7%) matches. Discussion Adverse sensitivities to food are diverse, and existing standard terminologies have gaps in their coverage of the breadth of allergy concepts. Conclusion New strategies are needed to represent and standardize food adverse sensitivity concepts, to improve documentation in EHRs. PMID:26384406

Food entries in a large allergy data repository.

PubMed

Plasek, Joseph M; Goss, Foster R; Lai, Kenneth H; Lau, Jason J; Seger, Diane L; Blumenthal, Kimberly G; Wickner, Paige G; Slight, Sarah P; Chang, Frank Y; Topaz, Maxim; Bates, David W; Zhou, Li

2016-04-01

Accurate food adverse sensitivity documentation in electronic health records (EHRs) is crucial to patient safety. This study examined, encoded, and grouped foods that caused any adverse sensitivity in a large allergy repository using natural language processing and standard terminologies. Using the Medical Text Extraction, Reasoning, and Mapping System (MTERMS), we processed both structured and free-text entries stored in an enterprise-wide allergy repository (Partners' Enterprise-wide Allergy Repository), normalized diverse food allergen terms into concepts, and encoded these concepts using the Systematized Nomenclature of Medicine - Clinical Terms (SNOMED-CT) and Unique Ingredient Identifiers (UNII) terminologies. Concept coverage also was assessed for these two terminologies. We further categorized allergen concepts into groups and calculated the frequencies of these concepts by group. Finally, we conducted an external validation of MTERMS's performance when identifying food allergen terms, using a randomized sample from a different institution. We identified 158 552 food allergen records (2140 unique terms) in the Partners repository, corresponding to 672 food allergen concepts. High-frequency groups included shellfish (19.3%), fruits or vegetables (18.4%), dairy (9.0%), peanuts (8.5%), tree nuts (8.5%), eggs (6.0%), grains (5.1%), and additives (4.7%). Ambiguous, generic concepts such as "nuts" and "seafood" accounted for 8.8% of the records. SNOMED-CT covered more concepts than UNII in terms of exact (81.7% vs 68.0%) and partial (14.3% vs 9.7%) matches. Adverse sensitivities to food are diverse, and existing standard terminologies have gaps in their coverage of the breadth of allergy concepts. New strategies are needed to represent and standardize food adverse sensitivity concepts, to improve documentation in EHRs. © The Author 2015. Published by Oxford University Press on behalf of the American Medical Informatics Association. All rights reserved. For

Semantic Linking of Learning Object Repositories to DBpedia

ERIC Educational Resources Information Center

Lama, Manuel; Vidal, Juan C.; Otero-Garcia, Estefania; Bugarin, Alberto; Barro, Senen

2012-01-01

Large-sized repositories of learning objects (LOs) are difficult to create and also to maintain. In this paper we propose a way to reduce this drawback by improving the classification mechanisms of the LO repositories. Specifically, we present a solution to automate the LO classification of the Universia repository, a collection of more than 15…

NCI Mouse Repository | Frederick National Laboratory for Cancer Research

Cancer.gov

The NCI Mouse Repository is an NCI-funded resource for mouse cancer models and associated strains. The repository makes strains available to all members of the scientific community (academic, non-profit, and commercial). NCI Mouse Repository strains

Phase III: Implementation and Operation of the Repository

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

1998-07-01

The metadata catalog was brought online for public access May 14, 1998. Since then dozens of users have registered and began to access the system. The system was demonstrated at the AAPG annual meeting in Salt Lake City and the EAGE (European Association of Geoscientists and Engineers) annual meeting in Leipzig, Germany. Hart Publications and PTTC "NetworkNews" have published articles about the metadata catalog, and articles for the AAPG Explorer and GSA Today are being developed. A back-up system at AGI headquarters was established. In support of the metadata catalog system, a leased-line Internet connection and two servers were installed.more » Porting of the GeoTrek server software to the new systems has begun. The back-up system will be operational during the 3 rd quarter of 1998 and will serve the NGDRS needs during periods when access to the site in Houston is down. Additionally, experimentation with new data types and deployment schemes will be tested on the system at AGI. The NGDRS has picked-up additional endorsements from the American Association of State Geologists, the MMS Outer Continental Shelf Policy Committee, and a new endorsement is being formulated by the AAPG Core Preservation Committee for consideration by the AAPG Executive Committee. The Texas Bureau of Economic Geology (BEG) is currently geocoding the well locations for the metadata catalog. Also, they have solicited proposals for the development of a core inventory control system that will work hand-in-hand with GeoTrek. A contract for that system will probably be given during the 3 rd quarter of 1998. The Texas Railroad Commission proposes to test the application of GeoTrek for accessing data in a joint project with the BEG. Several data transfer projects are underway. Vastar has committed to the transfer of 2D Appalachian seismic lines to the NDGRS clearinghouse. Receiving repositories have been identified and the final preparations are being made for transfer to these public

Monitored Geologic Repository Project Description Document

DOE Office of Scientific and Technical Information (OSTI.GOV)

P. M. Curry

2001-01-30

The primary objective of the Monitored Geologic Repository Project Description Document (PDD) is to allocate the functions, requirements, and assumptions to the systems at Level 5 of the Civilian Radioactive Waste Management System (CRWMS) architecture identified in Section 4. It provides traceability of the requirements to those contained in Section 3 of the ''Monitored Geologic Repository Requirements Document'' (MGR RD) (YMP 2000a) and other higher-level requirements documents. In addition, the PDD allocates design related assumptions to work products of non-design organizations. The document provides Monitored Geologic Repository (MGR) technical requirements in support of design and performance assessment in preparing formore » the Site Recommendation (SR) and License Application (LA) milestones. The technical requirements documented in the PDD are to be captured in the System Description Documents (SDDs) which address each of the systems at Level 5 of the CRWMS architecture. The design engineers obtain the technical requirements from the SDDs and by reference from the SDDs to the PDD. The design organizations and other organizations will obtain design related assumptions directly from the PDD. These organizations may establish additional assumptions for their individual activities, but such assumptions are not to conflict with the assumptions in the PDD. The PDD will serve as the primary link between the technical requirements captured in the SDDs and the design requirements captured in US Department of Energy (DOE) documents. The approved PDD is placed under Level 3 baseline control by the CRWMS Management and Operating Contractor (M and O) and the following portions of the PDD constitute the Technical Design Baseline for the MGR: the design characteristics listed in Table 1-1, the MGR Architecture (Section 4.1), the Technical Requirements (Section 5), and the Controlled Project Assumptions (Section 6).« less

Creation of Data Repositories to Advance Nursing Science.

PubMed

Perazzo, Joseph; Rodriguez, Margaret; Currie, Jackson; Salata, Robert; Webel, Allison R

2017-12-01

Data repositories are a strategy in line with precision medicine and big data initiatives, and are an efficient way to maximize data utility and form collaborative research relationships. Nurse researchers are uniquely positioned to make a valuable contribution using this strategy. The purpose of this article is to present a review of the benefits and challenges associated with developing data repositories, and to describe the process we used to develop and maintain a data repository in HIV research. Systematic planning, data collection, synthesis, and data sharing have enabled us to conduct robust cross-sectional and longitudinal analyses with more than 200 people living with HIV. Our repository building has also led to collaboration and training, both in and out of our organization. We present a pragmatic and affordable way that nurse scientists can build and maintain a data repository, helping us continue to make to our understanding of health phenomena.

Final repository for Denmark's low- and intermediate level radioactive waste

NASA Astrophysics Data System (ADS)

Nilsson, B.; Gravesen, P.; Petersen, S. S.; Binderup, M.

2012-12-01

Bertel Nilsson*, Peter Gravesen, Stig A. Schack Petersen, Merete Binderup Geological Survey of Denmark and Greenland (GEUS), Øster Voldgade 10, 1350 Copenhagen, Denmark, * email address bn@geus.dk The Danish Parliament decided in 2003 that the temporal disposal of the low- and intermediate level radioactive waste at the nuclear facilities at Risø should find another location for a final repository. The Danish radioactive waste must be stored on Danish land territory (exclusive Greenland) and must hold the entire existing radioactive waste, consisting of the waste from the decommissioning of the nuclear facilities at Risø, and the radioactive waste produced in Denmark from hospitals, universities and industry. The radioactive waste is estimated to a total amount of up to 10,000 m3. The Geological Survey of Denmark and Greenland, GEUS, is responsible for the geological studies of suitable areas for the repository. The task has been to locate and recognize non-fractured Quaternary and Tertiary clays or Precambrian bedrocks with low permeability which can isolate the radioactive waste from the surroundings the coming more than 300 years. Twenty two potential areas have been located and sequential reduced to the most favorable two to three locations taking into consideration geology, hydrogeology, nature protection and climate change conditions. Further detailed environmental and geology investigations will be undertaken at the two to three potential localities in 2013 to 2015. This study together with a study of safe transport of the radioactive waste and an investigation of appropriate repository concepts in relation to geology and safety analyses will constitute the basis upon which the final decision by the Danish Parliament on repository concept and repository location. The final repository is planned to be established and in operation at the earliest 2020.

Proteomics data repositories

PubMed Central

Riffle, Michael; Eng, Jimmy K.

2010-01-01

The field of proteomics, particularly the application of mass spectrometry analysis to protein samples, is well-established and growing rapidly. Proteomics studies generate large volumes of raw experimental data and inferred biological results. To facilitate the dissemination of these data, centralized data repositories have been developed that make the data and results accessible to proteomics researchers and biologists alike. This review of proteomics data repositories focuses exclusively on freely-available, centralized data resources that disseminate or store experimental mass spectrometry data and results. The resources chosen reflect a current “snapshot” of the state of resources available with an emphasis placed on resources that may be of particular interest to yeast researchers. Resources are described in terms of their intended purpose and the features and functionality provided to users. PMID:19795424

Optimizing procedures for a human genome repository. Final report, June 1, 1988--November 30, 1990

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nierman, W.C.

1991-03-01

Large numbers of clones will be generated during the Human Genome Project. As each is characterized, subsets will be identified which are useful to the scientific community at large. These subsets are most readily distributed through public repositories. The American Type Culture Collection (ATCC) is experienced in repository operation, but before this project had no history in managing clones and associated information in large batches instead of individually. This project permitted the ATCC to develop several procedures for automating and thus reducing the cost of characterizing, preserving, and maintaining information about clones.

Air and groundwater flow at the interface between fractured host rock and a bentonite buffer

NASA Astrophysics Data System (ADS)

Dessirier, B.; Jarsjo, J.; Frampton, A.

2014-12-01

Designs of deep geological repositories for spent nuclear fuel include several levels of confinement. The Swedish and Finnish concept KBS-3 targets for example sparsely fractured crystalline bedrock as host formation and would have the waste canisters embedded in an engineered buffer of compacted MX-80 bentonite. The host rock is a highly heterogeneous dual porosity material containing fractures and a rock matrix. Bentonite is a complex expansive porous material. Its water content and mechanical properties are interdependent. Beyond the specific physics of unsaturated flow and transport in each medium, the interface between them is critical. Detailed knowledge of the transitory two-phase flow regime, induced by the insertion of the unsaturated buffer in a saturated rock environment, is necessary to assess the performance of planned KBS-3 deposition holes. A set of numerical simulations based on the equations of two-phase flow for water and air in porous media were conducted to investigate the dynamics of air and groundwater flow near the rock/bentonite interface in the period following installation of the unsaturated bentonite buffer. We assume state of the two-phase flow parameter values for bentonite from laboratory water uptake tests and typical fracture and rock properties from the Äspö Hard rock laboratory (Sweden) gathered under several field characterization campaigns. The results point to desaturation of the rock domain as far as 10 cm away from the interface into matrix-dominated regions for up to 160 days. Similar observations were made during the Bentonite Rock Interaction Experiment (BRIE) at the Äspö HRL, with a desaturation sustained for even longer times. More than the mere time to mechanical and hydraulic equilibrium, the occurrence of sustained unsaturated conditions opens the possibility for biogeochemical processes that could be critical in the safety assessment of the planned repository.

Personal Name Identification in the Practice of Digital Repositories

ERIC Educational Resources Information Center

Xia, Jingfeng

2006-01-01

Purpose: To propose improvements to the identification of authors' names in digital repositories. Design/methodology/approach: Analysis of current name authorities in digital resources, particularly in digital repositories, and analysis of some features of existing repository applications. Findings: This paper finds that the variations of authors'…

Unifying Access to National Hydrologic Data Repositories via Web Services

NASA Astrophysics Data System (ADS)

Valentine, D. W.; Jennings, B.; Zaslavsky, I.; Maidment, D. R.

2006-12-01

The CUAHSI hydrologic information system (HIS) is designed to be a live, multiscale web portal system for accessing, querying, visualizing, and publishing distributed hydrologic observation data and models for any location or region in the United States. The HIS design follows the principles of open service oriented architecture, i.e. system components are represented as web services with well defined standard service APIs. WaterOneFlow web services are the main component of the design. The currently available services have been completely re-written compared to the previous version, and provide programmatic access to USGS NWIS. (steam flow, groundwater and water quality repositories), DAYMET daily observations, NASA MODIS, and Unidata NAM streams, with several additional web service wrappers being added (EPA STORET, NCDC and others.). Different repositories of hydrologic data use different vocabularies, and support different types of query access. Resolving semantic and structural heterogeneities across different hydrologic observation archives and distilling a generic set of service signatures is one of the main scalability challenges in this project, and a requirement in our web service design. To accomplish the uniformity of the web services API, data repositories are modeled following the CUAHSI Observation Data Model. The web service responses are document-based, and use an XML schema to express the semantics in a standard format. Access to station metadata is provided via web service methods, GetSites, GetSiteInfo and GetVariableInfo. The methdods form the foundation of CUAHSI HIS discovery interface and may execute over locally-stored metadata or request the information from remote repositories directly. Observation values are retrieved via a generic GetValues method which is executed against national data repositories. The service is implemented in ASP.Net, and other providers are implementing WaterOneFlow services in java. Reference implementation of

A strategy to establish Food Safety Model Repositories.

PubMed

Plaza-Rodríguez, C; Thoens, C; Falenski, A; Weiser, A A; Appel, B; Kaesbohrer, A; Filter, M

2015-07-02

Transferring the knowledge of predictive microbiology into real world food manufacturing applications is still a major challenge for the whole food safety modelling community. To facilitate this process, a strategy for creating open, community driven and web-based predictive microbial model repositories is proposed. These collaborative model resources could significantly improve the transfer of knowledge from research into commercial and governmental applications and also increase efficiency, transparency and usability of predictive models. To demonstrate the feasibility, predictive models of Salmonella in beef previously published in the scientific literature were re-implemented using an open source software tool called PMM-Lab. The models were made publicly available in a Food Safety Model Repository within the OpenML for Predictive Modelling in Food community project. Three different approaches were used to create new models in the model repositories: (1) all information relevant for model re-implementation is available in a scientific publication, (2) model parameters can be imported from tabular parameter collections and (3) models have to be generated from experimental data or primary model parameters. All three approaches were demonstrated in the paper. The sample Food Safety Model Repository is available via: http://sourceforge.net/projects/microbialmodelingexchange/files/models and the PMM-Lab software can be downloaded from http://sourceforge.net/projects/pmmlab/. This work also illustrates that a standardized information exchange format for predictive microbial models, as the key component of this strategy, could be established by adoption of resources from the Systems Biology domain. Copyright © 2015. Published by Elsevier B.V.

Software Repository

NASA Technical Reports Server (NTRS)

Merwarth, P., D.

1983-01-01

The Common Software Module Repository (CSMR) is computerized library system with high product and service visibility to potential users. Online capabilities of system allow both librarian and user to interact with library. Librarian is responsible for maintaining information in CSMR library. User searches library to locate software modules that meet his or her current needs.

10 CFR 51.67 - Environmental information concerning geologic repositories.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Environmental information concerning geologic repositories... information concerning geologic repositories. (a) In lieu of an environmental report, the Department of Energy... connection with any geologic repository developed under Subtitle A of Title I, or under Title IV, of the...

Harvesting NASA's Common Metadata Repository

NASA Astrophysics Data System (ADS)

Shum, D.; Mitchell, A. E.; Durbin, C.; Norton, J.

2017-12-01

As part of NASA's Earth Observing System Data and Information System (EOSDIS), the Common Metadata Repository (CMR) stores metadata for over 30,000 datasets from both NASA and international providers along with over 300M granules. This metadata enables sub-second discovery and facilitates data access. While the CMR offers a robust temporal, spatial and keyword search functionality to the general public and international community, it is sometimes more desirable for international partners to harvest the CMR metadata and merge the CMR metadata into a partner's existing metadata repository. This poster will focus on best practices to follow when harvesting CMR metadata to ensure that any changes made to the CMR can also be updated in a partner's own repository. Additionally, since each partner has distinct metadata formats they are able to consume, the best practices will also include guidance on retrieving the metadata in the desired metadata format using CMR's Unified Metadata Model translation software.

CAED Document Repository

EPA Pesticide Factsheets

Compliance Assurance and Enforcement Division Document Repository (CAEDDOCRESP) provides internal and external access of Inspection Records, Enforcement Actions, and National Environmental Protection Act (NEPA) documents to all CAED staff. The respository will also include supporting documents, images, etc.

Core Certification of Data Repositories: Trustworthiness and Long-Term Stewardship

NASA Astrophysics Data System (ADS)

de Sherbinin, A. M.; Mokrane, M.; Hugo, W.; Sorvari, S.; Harrison, S.

2017-12-01

Scientific integrity and norms dictate that data created and used by scientists should be managed, curated, and archived in trustworthy data repositories thus ensuring that science is verifiable and reproducible while preserving the initial investment in collecting data. Research stakeholders including researchers, science funders, librarians, and publishers must also be able to establish the trustworthiness of data repositories they use to confirm that the data they submit and use remain useful and meaningful in the long term. Data repositories are increasingly recognized as a key element of the global research infrastructure and the importance of establishing their trustworthiness is recognised as a prerequisite for efficient scientific research and data sharing. The Core Trustworthy Data Repository Requirements are a set of universal requirements for certification of data repositories at the core level (see: https://goo.gl/PYsygW). They were developed by the ICSU World Data System (WDS: www.icsu-wds.org) and the Data Seal of Approval (DSA: www.datasealofapproval.org)—the two authoritative organizations responsible for the development and implementation of this standard to be further developed under the CoreTrustSeal branding . CoreTrustSeal certification of data repositories involves a minimally intensive process whereby repositories supply evidence that they are sustainable and trustworthy. Repositories conduct a self-assessment which is then reviewed by community peers. Based on this review CoreTrustSeal certification is granted by the CoreTrustSeal Standards and Certification Board. Certification helps data communities—producers, repositories, and consumers—to improve the quality and transparency of their processes, and to increase awareness of and compliance with established standards. This presentation will introduce the CoreTrustSeal certification requirements for repositories and offer an opportunity to discuss ways to improve the contribution of

Asset Reuse of Images from a Repository

ERIC Educational Resources Information Center

Herman, Deirdre

2014-01-01

According to Markus's theory of reuse, when digital repositories are deployed to collect and distribute organizational assets, they supposedly help ensure accountability, extend information exchange, and improve productivity. Such repositories require a large investment due to the continuing costs of hardware, software, user licenses, training,…

Comparison of three commercial knowledge bases for detection of drug-drug interactions in clinical decision support.

PubMed

Fung, Kin Wah; Kapusnik-Uner, Joan; Cunningham, Jean; Higby-Baker, Stefanie; Bodenreider, Olivier

2017-07-01

To compare 3 commercial knowledge bases (KBs) used for detection and avoidance of potential drug-drug interactions (DDIs) in clinical practice. Drugs in the DDI tables from First DataBank (FDB), Micromedex, and Multum were mapped to RxNorm. The KBs were compared at the clinical drug, ingredient, and DDI rule levels. The KBs were evaluated against a reference list of highly significant DDIs from the Office of the National Coordinator for Health Information Technology (ONC). The KBs and the ONC list were applied to a prescription data set to simulate their use in clinical decision support. The KBs contained 1.6 million (FDB), 4.5 million (Micromedex), and 4.8 million (Multum) clinical drug pairs. Altogether, there were 8.6 million unique pairs, of which 79% were found only in 1 KB and 5% in all 3 KBs. However, there was generally more agreement than disagreement in the severity rankings, especially in the contraindicated category. The KBs covered 99.8-99.9% of the alerts of the ONC list and would have generated 25 (FDB), 145 (Micromedex), and 84 (Multum) alerts per 1000 prescriptions. The commercial KBs differ considerably in size and quantity of alerts generated. There is less variability in severity ranking of DDIs than suggested by previous studies. All KBs provide very good coverage of the ONC list. More work is needed to standardize the editorial policies and evidence for inclusion of DDIs to reduce variation among knowledge sources and improve relevance. Some DDIs considered contraindicated in all 3 KBs might be possible candidates to add to the ONC list. Published by Oxford University Press on behalf of the American Medical Informatics Association 2017. This work is written by US Government employees and is in the public domain in the United States.

Shared Medical Imaging Repositories.

PubMed

Lebre, Rui; Bastião, Luís; Costa, Carlos

2018-01-01

This article describes the implementation of a solution for the integration of ownership concept and access control over medical imaging resources, making possible the centralization of multiple instances of repositories. The proposed architecture allows the association of permissions to repository resources and delegation of rights to third entities. It includes a programmatic interface for management of proposed services, made available through web services, with the ability to create, read, update and remove all components resulting from the architecture. The resulting work is a role-based access control mechanism that was integrated with Dicoogle Open-Source Project. The solution has several application scenarios like, for instance, collaborative platforms for research and tele-radiology services deployed at Cloud.

Description of public health nursing nutrition assessment and interventions for home-visited women.

PubMed

Horning, Melissa L; Olsen, Jeanette M; Lell, Shay; Thorson, Diane R; Monsen, Karen A

2018-05-09

The purpose of this manuscript was to describe: Public Health Nurse (PHN) home-visited, female client Nutrition Knowledge (K), Behavior (B), and Status (S); the number and types of nutrition interventions PHNs used with these clients; and the types of clients receiving nutrition interventions. This descriptive study used PHN-generated Omaha System, electronic health record data from January 2012 to July 2015. The analytic sample contains 558 women who received home visits in a rural Midwestern U.S. county that employed universal nutrition assessment for clients. Omaha System data included nutrition KBS scores (from 1 = low to 5 = high) and nutrition interventions delivered. Analyses included descriptive, bivariate, and multivariate analyses (means, frequencies, chi-squares, general linear models). PHNs assessed nutrition KBS scores for 84.1% of clients; average Nutrition Knowledge was 3.4 (SD = 0.7), Behavior 3.7 (SD = 0.8), and Status 4.3 (SD = 1.0). PHNs provided 0-36 nutrition interventions per client. Nutrition intervention patterns were detected by the type of visit clients received. Results suggest home-visited women have room to improve Nutrition KBS and PHNs utilize myriad nutrition interventions. Results also point to opportunities to improve home-visited client care by providing more nutrition interventions, especially to those not receiving interventions, and revising standard care plans to reflect important Case Management nutrition interventions. © 2018 Wiley Periodicals, Inc.

Digital Repositories and the Question of Data Usefulness

NASA Astrophysics Data System (ADS)

Hughes, J. S.; Downs, R. R.

2017-12-01

The advent of ISO standards for trustworthy long-term digital repositories provides both a set of principles to develop long-term data repositories and the instruments to assess them for trustworthiness. Such mandatory high-level requirements are broad enough to be achievable, to some extent, by many scientific data centers, archives, and other repositories. But the requirement that the data be useful in the future, the requirement that is usually considered to be most relevant to the value of the repository for its user communities, largely remains subject to various interpretations and misunderstanding. However, current and future users will be relying on repositories to preserve and disseminate the data and information needed to discover, understand, and utilize these resources to support their research, learning, and decision-making objectives. Therefore, further study is needed to determine the approaches that can be adopted by repositories to make data useful to future communities of users. This presentation will describe approaches for enabling scientific data and related information, such as software, to be useful for current and potential future user communities and will present the methodology chosen to make one science discipline's data useful for both current and future users. The method uses an ontology-based information model to define and capture the information necessary to make the data useful for contemporary and future users.

Analytical model for screening potential CO2 repositories

USGS Publications Warehouse

Okwen, R.T.; Stewart, M.T.; Cunningham, J.A.

2011-01-01

Assessing potential repositories for geologic sequestration of carbon dioxide using numerical models can be complicated, costly, and time-consuming, especially when faced with the challenge of selecting a repository from a multitude of potential repositories. This paper presents a set of simple analytical equations (model), based on the work of previous researchers, that could be used to evaluate the suitability of candidate repositories for subsurface sequestration of carbon dioxide. We considered the injection of carbon dioxide at a constant rate into a confined saline aquifer via a fully perforated vertical injection well. The validity of the analytical model was assessed via comparison with the TOUGH2 numerical model. The metrics used in comparing the two models include (1) spatial variations in formation pressure and (2) vertically integrated brine saturation profile. The analytical model and TOUGH2 show excellent agreement in their results when similar input conditions and assumptions are applied in both. The analytical model neglects capillary pressure and the pressure dependence of fluid properties. However, simulations in TOUGH2 indicate that little error is introduced by these simplifications. Sensitivity studies indicate that the agreement between the analytical model and TOUGH2 depends strongly on (1) the residual brine saturation, (2) the difference in density between carbon dioxide and resident brine (buoyancy), and (3) the relationship between relative permeability and brine saturation. The results achieved suggest that the analytical model is valid when the relationship between relative permeability and brine saturation is linear or quasi-linear and when the irreducible saturation of brine is zero or very small. ?? 2011 Springer Science+Business Media B.V.

17 CFR 49.26 - Disclosure requirements of swap data repositories.

Code of Federal Regulations, 2014 CFR

2014-04-01

... data repository's policies and procedures reasonably designed to protect the privacy of any and all... swap data repositories. 49.26 Section 49.26 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION (CONTINUED) SWAP DATA REPOSITORIES § 49.26 Disclosure requirements of swap data...

Optimizing Resources for Trustworthiness and Scientific Impact of Domain Repositories

NASA Astrophysics Data System (ADS)

Lehnert, K.

2017-12-01

Domain repositories, i.e. data archives tied to specific scientific communities, are widely recognized and trusted by their user communities for ensuring a high level of data quality, enhancing data value, access, and reuse through a unique combination of disciplinary and digital curation expertise. Their data services are guided by the practices and values of the specific community they serve and designed to support the advancement of their science. Domain repositories need to meet user expectations for scientific utility in order to be successful, but they also need to fulfill the requirements for trustworthy repository services to be acknowledged by scientists, funders, and publishers as a reliable facility that curates and preserves data following international standards. Domain repositories therefore need to carefully plan and balance investments to optimize the scientific impact of their data services and user satisfaction on the one hand, while maintaining a reliable and robust operation of the repository infrastructure on the other hand. Staying abreast of evolving repository standards to certify as a trustworthy repository and conducting a regular self-assessment and certification alone requires resources that compete with the demands for improving data holdings or usability of systems. The Interdisciplinary Earth Data Alliance (IEDA), a data facility funded by the US National Science Foundation, operates repositories for geochemical, marine Geoscience, and Antarctic research data, while also maintaining data products (global syntheses) and data visualization and analysis tools that are of high value for the science community and have demonstrated considerable scientific impact. Balancing the investments in the growth and utility of the syntheses with resources required for certifcation of IEDA's repository services has been challenging, and a major self-assessment effort has been difficult to accommodate. IEDA is exploring a partnership model to share

WIPP Repository Reconfiguration

EPA Pesticide Factsheets

On August 30, 2011, the U.S. Department of Energy (DOE) provided a proposed planned change request that will relocate Panels 9 and 10 from the main north-south access drifts to south of the existing Panels 4 and 5 in the WIPP repository.

17 CFR 49.26 - Disclosure requirements of swap data repositories.

Code of Federal Regulations, 2013 CFR

2013-04-01

... TRADING COMMISSION SWAP DATA REPOSITORIES § 49.26 Disclosure requirements of swap data repositories... swap data repository shall furnish to the reporting entity a disclosure document that contains the... 17 Commodity and Securities Exchanges 1 2013-04-01 2013-04-01 false Disclosure requirements of...

17 CFR 49.26 - Disclosure requirements of swap data repositories.

Code of Federal Regulations, 2012 CFR

2012-04-01

... TRADING COMMISSION SWAP DATA REPOSITORIES § 49.26 Disclosure requirements of swap data repositories... swap data repository shall furnish to the reporting entity a disclosure document that contains the... 17 Commodity and Securities Exchanges 1 2012-04-01 2012-04-01 false Disclosure requirements of...

Central Satellite Data Repository Supporting Research and Development

NASA Astrophysics Data System (ADS)

Han, W.; Brust, J.

2015-12-01

Near real-time satellite data is critical to many research and development activities of atmosphere, land, and ocean processes. Acquiring and managing huge volumes of satellite data without (or with less) latency in an organization is always a challenge in the big data age. An organization level data repository is a practical solution to meeting this challenge. The STAR (Center for Satellite Applications and Research of NOAA) Central Data Repository (SCDR) is a scalable, stable, and reliable repository to acquire, manipulate, and disseminate various types of satellite data in an effective and efficient manner. SCDR collects more than 200 data products, which are commonly used by multiple groups in STAR, from NOAA, GOES, Metop, Suomi NPP, Sentinel, Himawari, and other satellites. The processes of acquisition, recording, retrieval, organization, and dissemination are performed in parallel. Multiple data access interfaces, like FTP, FTPS, HTTP, HTTPS, and RESTful, are supported in the SCDR to obtain satellite data from their providers through high speed internet. The original satellite data in various raster formats can be parsed in the respective adapter to retrieve data information. The data information is ingested to the corresponding partitioned tables in the central database. All files are distributed equally on the Network File System (NFS) disks to balance the disk load. SCDR provides consistent interfaces (including Perl utility, portal, and RESTful Web service) to locate files of interest easily and quickly and access them directly by over 200 compute servers via NFS. SCDR greatly improves collection and integration of near real-time satellite data, addresses satellite data requirements of scientists and researchers, and facilitates their primary research and development activities.

The Geant4 physics validation repository

NASA Astrophysics Data System (ADS)

Wenzel, H.; Yarba, J.; Dotti, A.

2015-12-01

The Geant4 collaboration regularly performs validation and regression tests. The results are stored in a central repository and can be easily accessed via a web application. In this article we describe the Geant4 physics validation repository which consists of a relational database storing experimental data and Geant4 test results, a java API and a web application. The functionality of these components and the technology choices we made are also described.

The Geant4 physics validation repository

DOE PAGES

Wenzel, H.; Yarba, J.; Dotti, A.

2015-12-23

The Geant4 collaboration regularly performs validation and regression tests. The results are stored in a central repository and can be easily accessed via a web application. In this article we describe the Geant4 physics validation repository which consists of a relational database storing experimental data and Geant4 test results, a java API and a web application. Lastly, the functionality of these components and the technology choices we made are also described

Public acceptance for centralized storage and repositories of low-level waste session (Panel)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lutz, H.R.

1995-12-31

Participants from various parts of the world will provide a summary of their particular country`s approach to low-level waste management and the cost of public acceptance for low-level waste management facilities. Participants will discuss the number, geographic location, and type of low-level waste repositories and centralized storage facilities located in their countries. Each will discuss the amount, distribution, and duration of funds to gain public acceptance of these facilities. Participants will provide an estimated $/meter for centralized storage facilities and repositories. The panel will include a brief discussion about the ethical aspects of public acceptance costs, approaches for negotiating acceptance,more » and lessons learned in each country. The audience is invited to participate in the discussion.« less

Exploring Characterizations of Learning Object Repositories Using Data Mining Techniques

NASA Astrophysics Data System (ADS)

Segura, Alejandra; Vidal, Christian; Menendez, Victor; Zapata, Alfredo; Prieto, Manuel

Learning object repositories provide a platform for the sharing of Web-based educational resources. As these repositories evolve independently, it is difficult for users to have a clear picture of the kind of contents they give access to. Metadata can be used to automatically extract a characterization of these resources by using machine learning techniques. This paper presents an exploratory study carried out in the contents of four public repositories that uses clustering and association rule mining algorithms to extract characterizations of repository contents. The results of the analysis include potential relationships between different attributes of learning objects that may be useful to gain an understanding of the kind of resources available and eventually develop search mechanisms that consider repository descriptions as a criteria in federated search.

Assessing repository technology. Where do we go from here?

NASA Technical Reports Server (NTRS)

Eichmann, David

1992-01-01

Three sample information retrieval systems, archie, autoLib, and Wide Area Information Service (WAIS), are compared with regard to their expressiveness and usefulness, first in the general context of information retrieval, and then as prospective software reuse repositories. While the representational capabilities of these systems are limited, they provide a useful foundation for future repository efforts, particularly from the perspective of repository distribution and coherent user interface design.

Assessing repository technology: Where do we go from here?

NASA Technical Reports Server (NTRS)

Eichmann, David A.

1992-01-01

Three sample information retrieval systems, archie, autoLib, and Wide Area Information Service (WAIS), are compared with regard to their expressiveness and usefulness, first in the general context of information retrieval, and then as perspective software reuse repositories. While the representational capabilities of these systems are limited, they provide a useful foundation for future repository efforts, particularly from the perspective of repository distribution and coherent user interface design.

Biospecimen repositories and cytopathology.

PubMed

Krishnamurthy, Savitri

2015-03-01

Biospecimen repositories are important for the advancement of biomedical research. Literature on the potential for biobanking of fine-needle aspiration, gynecologic, and nongynecologic cytology specimens is very limited. The potential for biobanking of these specimens as valuable additional resources to surgically excised tissues appears to be excellent. The cervicovaginal specimens that can be used for biobanking include Papanicolaou-stained monolayer preparations and residual material from liquid-based cytology preparations. Different types of specimen preparations of fine-needle aspiration and nongynecologic specimens, including Papanicolaou-stained and Diff-Quik-stained smears, cell blocks. and dedicated passes/residual material from fine-needle aspiration stored frozen in a variety of solutions, can be used for biobanking. Because of several gaps in knowledge regarding the standard of operative procedures for the procurement, storage, and quality assessment of cytology specimens, further studies as well as national conferences and workshops are needed not only to create awareness but also to facilitate the use of cytopathology specimens for biobanking. © 2014 American Cancer Society.

The Use of Digital Repositories for Enhancing Teacher Pedagogical Performance

ERIC Educational Resources Information Center

Cohen, Anat; Kalimi, Sharon; Nachmias, Rafi

2013-01-01

This research examines the usage of local learning material repositories at school, as well as related teachers' attitudes and training. The study investigates the use of these repositories for enhancing teacher performance and assesses whether the assimilation of the local repositories increases their usage of and contribution to by teachers. One…

Institutional Repositories in Indian Universities and Research Institutes: A Study

ERIC Educational Resources Information Center

Krishnamurthy, M.; Kemparaju, T. D.

2011-01-01

Purpose: The purpose of this paper is to report on a study of the institutional repositories (IRs) in use in Indian universities and research institutes. Design/methodology/approach: Repositories in various institutions in India were accessed and described in a standardised way. Findings: The 20 repositories studied covered collections of diverse…

Repositories for Research: Southampton's Evolving Role in the Knowledge Cycle

ERIC Educational Resources Information Center

Simpson, Pauline; Hey, Jessie

2006-01-01

Purpose: To provide an overview of how open access (OA) repositories have grown to take a premier place in the e-research knowledge cycle and offer Southampton's route from project to sustainable institutional repository. Design/methodology/approach: The evolution of institutional repositories and OA is outlined raising questions of multiplicity…

10 CFR 960.3-2-3 - Recommendation of sites for characterization.

Code of Federal Regulations, 2010 CFR

2010-01-01

... POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-2-3 Recommendation of sites... characterization for the selection of the first repository, the Secretary shall recommend in writing to the..., and, after the first repository, consideration of regionality in §§ 960.3-1-1, 960.3-1-2, and 960.3-1...

NASA Biological Specimen Repository

NASA Technical Reports Server (NTRS)

Pietrzyk, Robert; McMonigal, K. A.; Sams, C. F.; Johnson, M. A.

2009-01-01

The NASA Biological Specimen Repository (NBSR) has been established to collect, process, annotate, store, and distribute specimens under the authority of the NASA/JSC Committee for the Protection of Human Subjects. The International Space Station (ISS) provides a platform to investigate the effects of microgravity on human physiology prior to lunar and exploration class missions. The NBSR is a secure controlled storage facility that is used to maintain biological specimens over extended periods of time, under well-controlled conditions, for future use in approved human spaceflight-related research protocols. The repository supports the Human Research Program, which is charged with identifying and investigating physiological changes that occur during human spaceflight, and developing and implementing effective countermeasures when necessary. The storage of crewmember samples from many different ISS flights in a single repository will be a valuable resource with which researchers can validate clinical hypotheses, study space-flight related changes, and investigate physiological markers All samples collected require written informed consent from each long duration crewmember. The NBSR collects blood and urine samples from all participating long duration ISS crewmembers. These biological samples are collected pre-flight at approximately 45 days prior to launch, during flight on flight days 15, 30, 60 120 and within 2 weeks of landing. Postflight sessions are conducted 3 and 30 days following landing. The number of inflight sessions is dependent on the duration of the mission. Operations began in 2007 and as of October 2009, 23 USOS crewmembers have completed or agreed to participate in this project. As currently planned, these human biological samples will be collected from crewmembers covering multiple ISS missions until the end of U.S. presence on the ISS or 2017. The NBSR will establish guidelines for sample distribution that are consistent with ethical principles

ADVANTG Shielding Analysis for Closure Operations in an Open-Mode Repository

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bevill, Aaron M; Radulescu, Georgeta; Scaglione, John M

2013-01-01

en-mode repository concepts could require worker entry into access drifts after placement of fuel casks in order to perform activities related to backfill, plug emplacement, routine maintenance, or performance confirmation. An ideal emplacement-drift shielding configuration would minimize dose to workers while maximizing airflow through the emplacement drifts. This paper presents a preliminary investigation of the feasibility and effectiveness of radiation shielding concepts that could be employed to facilitate worker operations in an open-mode repository. The repository model for this study includes pressurized-water reactor fuel assemblies (60 GWd/MTU burnup, 40 year post-irradiation cooldown) in packages of 32 assemblies. The closest fuelmore » packages are 5 meters from dosimetry voxels in the access drift. The unshielded dose to workers in the access drift is 73.7 rem/hour. Prior work suggests that open-mode repository concepts similar to this one would require 15 m3/s of ventilation airflow. Shielding concepts considered here include partial concrete plugs, labyrinthine shields, and stainless steel photon attenuator grids. Maximum dose to workers in the access drift was estimated for each shielding concept using MCNP5 with variance reduction parameters generated by ADVANTG. Because airflow through the shielding is important for open-mode repositories, a semi-empirical estimate of the head loss due to each shielding configuration was also calculated. Airflow and shielding performance vary widely among the proposed shielding configurations. Although the partial plug configuration had the best airflow performance, it allowed dose rates 1500 greater than the specified target. Labyrinthine shielding concepts yield doses on the order of 1 mrem/hour with configurations that impose 3 to 11 J/kg head loss. Adding 1 cm lead lining to the airflow channels of labyrinthine designs further reduces the worker dose by 65% to 95%. Photon-attenuator concepts may reduce

17 CFR 49.9 - Duties of registered swap data repositories.

Code of Federal Regulations, 2014 CFR

2014-04-01

... privacy of any and all swap data and any other related information that the swap data repository receives... 17 Commodity and Securities Exchanges 2 2014-04-01 2014-04-01 false Duties of registered swap data... (CONTINUED) SWAP DATA REPOSITORIES § 49.9 Duties of registered swap data repositories. (a) Duties. To be...

High Resolution 3d Imaging during the Construction of National Radioactive Waste Repository from BÁTAAPÁTI, Hungary

NASA Astrophysics Data System (ADS)

Gaich, A.; Deák, F.; Pötsch, M.

2012-12-01

The Hungarian National Radioactive Waste Repository is being built in the neighborhood of the village called Bátaapáti. The program of the new disposal facility for the low- and intermediate-level wastes (L/ILW) is conducted by PURAM (Public Limited Company for Radioactive Waste Management). The Bátaapáti underground research program began in February 2005, with the excavation of the two inclined exploratory tunnels. These tunnels have 30 m distance between their axes, 10% inclination and 1.7 km length, and have reached the 0 m Baltic sea-level in the Mórágy Granite Formation. The safety of nuclear repository mainly is influenced by the ground behaviour and its fracturing hence mapping of the geological features has a great importance. Because of the less stable ground, the cavern walls were shotcreted after every tunnelling advance. The site geologists were required to make the tunnel mapping after every drill and blast cycle. The time interval was short and the documenting work was unrepeatable due to the shotcrete supported walls, so it was very important to use a modern, precise system to create 3D photorealistic models of the rock surfaces on the excavated tunnel walls. We have chosen the photogrammetric method, because it has adequate resolution and quality for the photo combined 3D models. At the beginning, we had used the JointMetriX3D (JMX) system and subsequently ShapeMetriX3D (SMX) in the repository chamber excavation phase. From the acquired 3D images through geological mapping is performed as the system allows directly measuring geometric information on visible discontinuities such as dip and dip direction. Descriptive rock mass parameters such as spacing, area, roughness are instantly available. In this article we would like to continue that research having made by JMX model of a tunnel face of "TSZV" access tunnel and using SMX model of a tunnel face from "DEK" Chamber. Our studies were carried out by field engineering geologists on further

Monte Carlo simulations for generic granite repository studies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chu, Shaoping; Lee, Joon H; Wang, Yifeng

In a collaborative study between Los Alamos National Laboratory (LANL) and Sandia National Laboratories (SNL) for the DOE-NE Office of Fuel Cycle Technologies Used Fuel Disposition (UFD) Campaign project, we have conducted preliminary system-level analyses to support the development of a long-term strategy for geologic disposal of high-level radioactive waste. A general modeling framework consisting of a near- and a far-field submodel for a granite GDSE was developed. A representative far-field transport model for a generic granite repository was merged with an integrated systems (GoldSim) near-field model. Integrated Monte Carlo model runs with the combined near- and farfield transport modelsmore » were performed, and the parameter sensitivities were evaluated for the combined system. In addition, a sub-set of radionuclides that are potentially important to repository performance were identified and evaluated for a series of model runs. The analyses were conducted with different waste inventory scenarios. Analyses were also conducted for different repository radionuelide release scenarios. While the results to date are for a generic granite repository, the work establishes the method to be used in the future to provide guidance on the development of strategy for long-term disposal of high-level radioactive waste in a granite repository.« less

Harvesting NASA's Common Metadata Repository (CMR)

NASA Technical Reports Server (NTRS)

Shum, Dana; Durbin, Chris; Norton, James; Mitchell, Andrew

2017-01-01

As part of NASA's Earth Observing System Data and Information System (EOSDIS), the Common Metadata Repository (CMR) stores metadata for over 30,000 datasets from both NASA and international providers along with over 300M granules. This metadata enables sub-second discovery and facilitates data access. While the CMR offers a robust temporal, spatial and keyword search functionality to the general public and international community, it is sometimes more desirable for international partners to harvest the CMR metadata and merge the CMR metadata into a partner's existing metadata repository. This poster will focus on best practices to follow when harvesting CMR metadata to ensure that any changes made to the CMR can also be updated in a partner's own repository. Additionally, since each partner has distinct metadata formats they are able to consume, the best practices will also include guidance on retrieving the metadata in the desired metadata format using CMR's Unified Metadata Model translation software.

The Pediatric Imaging, Neurocognition, and Genetics (PING) Data Repository

PubMed Central

Jernigan, Terry L.; Brown, Timothy T.; Hagler, Donald J.; Akshoomoff, Natacha; Bartsch, Hauke; Newman, Erik; Thompson, Wesley K.; Bloss, Cinnamon S.; Murray, Sarah S.; Schork, Nicholas; Kennedy, David N.; Kuperman, Joshua M.; McCabe, Connor; Chung, Yoonho; Libiger, Ondrej; Maddox, Melanie; Casey, B. J.; Chang, Linda; Ernst, Thomas M.; Frazier, Jean A.; Gruen, Jeffrey R.; Sowell, Elizabeth R.; Kenet, Tal; Kaufmann, Walter E.; Mostofsky, Stewart; Amaral, David G.; Dale, Anders M.

2015-01-01

The main objective of the multi-site Pediatric Imaging, Neurocognition, and Genetics (PING) study was to create a large repository of standardized measurements of behavioral and imaging phenotypes accompanied by whole genome genotyping acquired from typically-developing children varying widely in age (3 to 20 years). This cross-sectional study produced sharable data from 1493 children, and these data have been described in several publications focusing on brain and cognitive development. Researchers may gain access to these data by applying for an account on the PING Portal and filing a Data Use Agreement. Here we describe the recruiting and screening of the children and give a brief overview of the assessments performed, the imaging methods applied, the genetic data produced, and the numbers of cases for whom different data types are available. We also cite sources of more detailed information about the methods and data. Finally we describe the procedures for accessing the data and for using the PING data exploration portal. PMID:25937488

National Pesticide Standard Repository

EPA Pesticide Factsheets

EPA's National Pesticide Standards Repository collects and maintains an inventory of analytical “standards” of registered pesticides in the United States, as well as some that are not currently registered for food and product testing and monitoring.

Interoperability Across the Stewardship Spectrum in the DataONE Repository Federation

NASA Astrophysics Data System (ADS)

Jones, M. B.; Vieglais, D.; Wilson, B. E.

2016-12-01

Thousands of earth and environmental science repositories serve many researchers and communities, each with their own community and legal mandates, sustainability models, and historical infrastructure. These repositories span the stewardship spectrum from highly curated collections that employ large numbers of staff members to review and improve data, to small, minimal budget repositories that accept data caveat emptor and where all responsibility for quality lies with the submitter. Each repository fills a niche, providing services that meet the stewardship tradeoffs of one or more communities. We have reviewed these stewardship tradeoffs for several DataONE member repositories ranging from minimally (KNB) to highly curated (Arctic Data Center), as well as general purpose (Dryad) to highly discipline or project specific (NEON). The rationale behind different levels of stewardship reflect resolution of these tradeoffs. Some repositories aim to encourage extensive uptake by keeping processes simple and minimizing the amount of information collected, but this limits the long-term utility of the data and the search, discovery, and integration systems that are possible. Other repositories require extensive metadata input, review, and assessment, allowing for excellent preservation, discovery, and integration but at the cost of significant time for submitters and expense for curatorial staff. DataONE recognizes these different levels of curation, and attempts to embrace them to create a federation that is useful across the stewardship spectrum. DataONE provides a tiered model for repositories with growing utility of DataONE services at higher tiers of curation. The lowest tier supports read-only access to data and requires little more than title and contact metadata. Repositories can gradually phase in support for higher levels of metadata and services as needed. These tiered capabilities are possible through flexible support for multiple metadata standards and services

Adapting a Clinical Data Repository to ICD-10-CM through the use of a Terminology Repository

PubMed Central

Cimino, James J.; Remennick, Lyubov

2014-01-01

Clinical data repositories frequently contain patient diagnoses coded with the International Classification of Diseases, Ninth Revision (ICD-9-CM). These repositories now need to accommodate data coded with the Tenth Revision (ICD-10-CM). Database users wish to retrieve relevant data regardless of the system by which they are coded. We demonstrate how a terminology repository (the Research Entities Dictionary or RED) serves as an ontology relating terms of both ICD versions to each other to support seamless version-independent retrieval from the Biomedical Translational Research Information System (BTRIS) at the National Institutes of Health. We make use of the Center for Medicare and Medicaid Services’ General Equivalence Mappings (GEMs) to reduce the modeling effort required to determine whether ICD-10-CM terms should be added to the RED as new concepts or as synonyms of existing concepts. A divide-and-conquer approach is used to develop integration heuristics that offer a satisfactory interim solution and facilitate additional refinement of the integration as time and resources allow. PMID:25954344

10 CFR 960.3-1-3 - Regionality.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 4 2013-01-01 2013-01-01 false Regionality. 960.3-1-3 Section 960.3-1-3 Energy DEPARTMENT OF ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-1-3 Regionality. In making site recommendations for repository...

10 CFR 960.3-1-3 - Regionality.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 4 2011-01-01 2011-01-01 false Regionality. 960.3-1-3 Section 960.3-1-3 Energy DEPARTMENT OF ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-1-3 Regionality. In making site recommendations for repository...

10 CFR 960.3-1-3 - Regionality.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 4 2014-01-01 2014-01-01 false Regionality. 960.3-1-3 Section 960.3-1-3 Energy DEPARTMENT OF ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-1-3 Regionality. In making site recommendations for repository...

10 CFR 960.3-1-3 - Regionality.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 4 2012-01-01 2012-01-01 false Regionality. 960.3-1-3 Section 960.3-1-3 Energy DEPARTMENT OF ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-1-3 Regionality. In making site recommendations for repository...

Evolution of a Digital Repository: One Institution's Experience

ERIC Educational Resources Information Center

Owen, Terry M.

2011-01-01

In this article, the development of a digital repository is examined, specifically how the focus on acquiring content for the repository has transitioned from faculty-published research to include the gray literature produced by the research centers on campus, including unpublished technical reports and undergraduate research from honors programs.…

Space Telecommunications Radio System (STRS) Application Repository Design and Analysis

NASA Technical Reports Server (NTRS)

Handler, Louis M.

2013-01-01

The Space Telecommunications Radio System (STRS) Application Repository Design and Analysis document describes the STRS application repository for software-defined radio (SDR) applications intended to be compliant to the STRS Architecture Standard. The document provides information about the submission of artifacts to the STRS application repository, to provide information to the potential users of that information, and for the systems engineer to understand the requirements, concepts, and approach to the STRS application repository. The STRS application repository is intended to capture knowledge, documents, and other artifacts for each waveform application or other application outside of its project so that when the project ends, the knowledge is retained. The document describes the transmission of technology from mission to mission capturing lessons learned that are used for continuous improvement across projects and supporting NASA Procedural Requirements (NPRs) for performing software engineering projects and NASAs release process.

[The subject repositories of strategy of the Open Access initiative].

PubMed

Soares Guimarães, M C; da Silva, C H; Horsth Noronha, I

2012-11-01

The subject repositories are defined as a set of digital objects resulting from the research related to a specific disciplinary field and occupy a still restricted space in the discussion agenda of the Free Access Movement when compared to amplitude reached in the discussion of Institutional Repositories. Although the Subject Repository comes to prominence in the field, especially for the success of initiatives such as the arXiv, PubMed and E-prints, the literature on the subject is recognized as very limited. Despite its roots in the Library and Information Science, and focus on the management of disciplinary collections (subject area literature), there is little information available about the development and management of subject repositories. The following text seeks to make a brief summary on the topic as a way to present the potential to develop subject repositories in order to strengthen the initiative of open access.

Identifying Tensions in the Use of Open Licenses in OER Repositories

ERIC Educational Resources Information Center

Amiel, Tel; Soares, Tiago Chagas

2016-01-01

We present an analysis of 50 repositories for educational content conducted through an "audit system" that helped us classify these repositories, their software systems, promoters, and how they communicated their licensing practices. We randomly accessed five resources from each repository to investigate the alignment of licensing…

A Digital Broadcast Item (DBI) enabling metadata repository for digital, interactive television (digiTV) feedback channel networks

NASA Astrophysics Data System (ADS)

Lugmayr, Artur R.; Mailaparampil, Anurag; Tico, Florina; Kalli, Seppo; Creutzburg, Reiner

2003-01-01

Digital television (digiTV) is an additional multimedia environment, where metadata is one key element for the description of arbitrary content. This implies adequate structures for content description, which is provided by XML metadata schemes (e.g. MPEG-7, MPEG-21). Content and metadata management is the task of a multimedia repository, from which digiTV clients - equipped with an Internet connection - can access rich additional multimedia types over an "All-HTTP" protocol layer. Within this research work, we focus on conceptual design issues of a metadata repository for the storage of metadata, accessible from the feedback channel of a local set-top box. Our concept describes the whole heterogeneous life-cycle chain of XML metadata from the service provider to the digiTV equipment, device independent representation of content, accessing and querying the metadata repository, management of metadata related to digiTV, and interconnection of basic system components (http front-end, relational database system, and servlet container). We present our conceptual test configuration of a metadata repository that is aimed at a real-world deployment, done within the scope of the future interaction (fiTV) project at the Digital Media Institute (DMI) Tampere (www.futureinteraction.tv).

Construction of quality-assured infant feeding process of care data repositories: Construction of the perinatal repository (Part 2).

PubMed

García-de-León-Chocano, Ricardo; Muñoz-Soler, Verónica; Sáez, Carlos; García-de-León-González, Ricardo; García-Gómez, Juan M

2016-04-01

This is the second in a series of two papers regarding the construction of data quality (DQ) assured repositories, based on population data from Electronic Health Records (EHR), for the reuse of information on infant feeding from birth until the age of two. This second paper describes the application of the computational process of constructing the first quality-assured repository for the reuse of information on infant feeding in the perinatal period, with the aim of studying relevant questions from the Baby Friendly Hospital Initiative (BFHI) and monitoring its deployment in our hospital. The construction of the repository was carried out using 13 semi-automated procedures to assess, recover or discard clinical data. The initial information consisted of perinatal forms from EHR related to 2048 births (Facts of Study, FoS) between 2009 and 2011, with a total of 433,308 observations of 223 variables. DQ was measured before and after the procedures using metrics related to eight quality dimensions: predictive value, correctness, duplication, consistency, completeness, contextualization, temporal-stability, and spatial-stability. Once the predictive variables were selected and DQ was assured, the final repository consisted of 1925 births, 107,529 observations and 73 quality-assured variables. The amount of discarded observations mainly corresponds to observations of non-predictive variables (52.90%) and the impact of the de-duplication process (20.58%) with respect to the total input data. Seven out of thirteen procedures achieved 100% of valid births, observations and variables. Moreover, 89% of births and ~98% of observations were consistent according to the experts׳ criteria. A multidisciplinary approach along with the quantification of DQ has allowed us to construct the first repository about infant feeding in the perinatal period based on EHR population data. Copyright © 2016 Elsevier Ltd. All rights reserved.

Generic repository design concepts and thermal analysis (FY11).

DOE Office of Scientific and Technical Information (OSTI.GOV)

Howard, Robert; Dupont, Mark; Blink, James A.

2011-08-01

Reference concepts for geologic disposal of used nuclear fuel and high-level radioactive waste in the U.S. are developed, including geologic settings and engineered barriers. Repository thermal analysis is demonstrated for a range of waste types from projected future, advanced nuclear fuel cycles. The results show significant differences among geologic media considered (clay/shale, crystalline rock, salt), and also that waste package size and waste loading must be limited to meet targeted maximum temperature values. In this study, the UFD R&D Campaign has developed a set of reference geologic disposal concepts for a range of waste types that could potentially be generatedmore » in advanced nuclear FCs. A disposal concept consists of three components: waste inventory, geologic setting, and concept of operations. Mature repository concepts have been developed in other countries for disposal of spent LWR fuel and HLW from reprocessing UNF, and these serve as starting points for developing this set. Additional design details and EBS concepts will be considered as the reference disposal concepts evolve. The waste inventory considered in this study includes: (1) direct disposal of SNF from the LWR fleet, including Gen III+ advanced LWRs being developed through the Nuclear Power 2010 Program, operating in a once-through cycle; (2) waste generated from reprocessing of LWR UOX UNF to recover U and Pu, and subsequent direct disposal of used Pu-MOX fuel (also used in LWRs) in a modified-open cycle; and (3) waste generated by continuous recycling of metal fuel from fast reactors operating in a TRU burner configuration, with additional TRU material input supplied from reprocessing of LWR UOX fuel. The geologic setting provides the natural barriers, and establishes the boundary conditions for performance of engineered barriers. The composition and physical properties of the host medium dictate design and construction approaches, and determine hydrologic and thermal responses

An open repositories network development for medical teaching resources.

PubMed

Soula, Gérard; Darmoni, Stefan; Le Beux, Pierre; Renard, Jean-Marie; Dahamna, Badisse; Fieschi, Marius

2010-01-01

The lack of interoperability between repositories of heterogeneous and geographically widespread data is an obstacle to the diffusion, sharing and reutilization of those data. We present the development of an open repositories network taking into account both the syntactic and semantic interoperability of the different repositories and based on international standards in this field. The network is used by the medical community in France for the diffusion and sharing of digital teaching resources. The syntactic interoperability of the repositories is managed using the OAI-PMH protocol for the exchange of metadata describing the resources. Semantic interoperability is based, on one hand, on the LOM standard for the description of resources and on MESH for the indexing of the latter and, on the other hand, on semantic interoperability management designed to optimize compliance with standards and the quality of the metadata.

Neural network-based retrieval from software reuse repositories

NASA Technical Reports Server (NTRS)

Eichmann, David A.; Srinivas, Kankanahalli

1992-01-01

A significant hurdle confronts the software reuser attempting to select candidate components from a software repository - discriminating between those components without resorting to inspection of the implementation(s). We outline an approach to this problem based upon neural networks which avoids requiring the repository administrators to define a conceptual closeness graph for the classification vocabulary.

10 CFR 960.3-1 - Siting provisions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... REPOSITORY Implementation Guidelines § 960.3-1 Siting provisions. The siting provisions establish the... repositories. As required by the Act, § 960.3-1-3 specifies consideration of a regional distribution of repositories after recommendation of a site for development of the first repository. Section 960.3-1-4...

Rolling Deck to Repository (R2R): Standards and Semantics for Open Access to Research Data

NASA Astrophysics Data System (ADS)

Arko, Robert; Carbotte, Suzanne; Chandler, Cynthia; Smith, Shawn; Stocks, Karen

2015-04-01

In recent years, a growing number of funding agencies and professional societies have issued policies calling for open access to research data. The Rolling Deck to Repository (R2R) program is working to ensure open access to the environmental sensor data routinely acquired by the U.S. academic research fleet. Currently 25 vessels deliver 7 terabytes of data to R2R each year, acquired from a suite of geophysical, oceanographic, meteorological, and navigational sensors on over 400 cruises worldwide. R2R is working to ensure these data are preserved in trusted repositories, discoverable via standard protocols, and adequately documented for reuse. R2R maintains a master catalog of cruises for the U.S. academic research fleet, currently holding essential documentation for over 3,800 expeditions including vessel and cruise identifiers, start/end dates and ports, project titles and funding awards, science parties, dataset inventories with instrument types and file formats, data quality assessments, and links to related content at other repositories. A Digital Object Identifier (DOI) is published for 1) each cruise, 2) each original field sensor dataset, 3) each post-field data product such as quality-controlled shiptrack navigation produced by the R2R program, and 4) each document such as a cruise report submitted by the science party. Scientists are linked to personal identifiers, such as the Open Researcher and Contributor ID (ORCID), where known. Using standard global identifiers such as DOIs and ORCIDs facilitates linking with journal publications and generation of citation metrics. Since its inception, the R2R program has worked in close collaboration with other data repositories in the development of shared semantics for oceanographic research. The R2R cruise catalog uses community-standard terms and definitions hosted by the NERC Vocabulary Server, and publishes ISO metadata records for each cruise that use community-standard profiles developed with the NOAA Data

Repository Drift Backfilling Demonstrator

DOE Office of Scientific and Technical Information (OSTI.GOV)

Londe, I.; Dubois, J.Ph.; Bauer, C.

2008-07-01

The 'Backfilling Demonstrator' is one of the technological demonstrators developed by ANDRA in the framework of the feasibility studies for a geological repository for high-level long-lived (HL-LL waste) within a clay formation. The demonstrator concerns the standard and supporting backfills as defined in Andra's 2005 design. The standard backfill is intended to fill up almost all drifts of the underground repository in order to limit any deformation of the rock after the degradation of the drift lining. The supporting backfill only concerns a small portion of the volume to be backfilled in order to counter the swelling pressure of themore » swelling clay contained in the sealing structures. The first objective of the demonstrator was to show the possibility of manufacturing a satisfactory backfill, in spite of the exiguity of the underground structures, and of reusing as much as possible the argillite muck. For the purpose of this experiment, the argillite muck was collected on Andra's work-site for the implementation of an underground research laboratory. Still ongoing, the second objective is to follow up the long-term evolution of the backfill. Approximately 200 m{sup 3} of compacted backfill material have been gathered in a large concrete tube simulating a repository drift. The standard backfill was manufactured exclusively with argillite. The supporting backfill was made by forming a mixture of argillite and sand. Operations were carried out mostly at Richwiller, close to Mulhouse, France. The objectives of the demonstrator were met: an application method was tested and proven satisfactory. The resulting dry densities are relatively high, although the moduli of deformation do not always reach the set goal. The selected objective for the demonstrator was a dry density corresponding to a relatively high compaction level (95% of the standard Proctor optimum [SPO]), for both pure argillite and the argillite-sand mixture. The plate-percussion compaction

Developing criteria to establish Trusted Digital Repositories

USGS Publications Warehouse

Faundeen, John L.

2017-01-01

This paper details the drivers, methods, and outcomes of the U.S. Geological Survey’s quest to establish criteria by which to judge its own digital preservation resources as Trusted Digital Repositories. Drivers included recent U.S. legislation focused on data and asset management conducted by federal agencies spending $100M USD or more annually on research activities. The methods entailed seeking existing evaluation criteria from national and international organizations such as International Standards Organization (ISO), U.S. Library of Congress, and Data Seal of Approval upon which to model USGS repository evaluations. Certification, complexity, cost, and usability of existing evaluation models were key considerations. The selected evaluation method was derived to allow the repository evaluation process to be transparent, understandable, and defensible; factors that are critical for judging competing, internal units. Implementing the chosen evaluation criteria involved establishing a cross-agency, multi-disciplinary team that interfaced across the organization. 

Collaboration Nation: The Building of the Welsh Repository Network

ERIC Educational Resources Information Center

Knowles, Jacqueline

2010-01-01

Purpose: The purpose of this paper is to disseminate information about the Welsh Repository Network (WRN), innovative work being undertaken to build an integrated network of institutional digital repositories. A collaborative approach, in particular through the provision of centralised technical and organisational support, has demonstrated…

Microsoft Repository Version 2 and the Open Information Model.

ERIC Educational Resources Information Center

Bernstein, Philip A.; Bergstraesser, Thomas; Carlson, Jason; Pal, Shankar; Sanders, Paul; Shutt, David

1999-01-01

Describes the programming interface and implementation of the repository engine and the Open Information Model for Microsoft Repository, an object-oriented meta-data management facility that ships in Microsoft Visual Studio and Microsoft SQL Server. Discusses Microsoft's component object model, object manipulation, queries, and information…

17 CFR 49.19 - Core principles applicable to registered swap data repositories.

Code of Federal Regulations, 2014 CFR

2014-04-01

... registered swap data repositories. 49.19 Section 49.19 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION (CONTINUED) SWAP DATA REPOSITORIES § 49.19 Core principles applicable to registered swap data repositories. (a) Compliance with core principles. To be registered, and maintain...

Developing an Integrated Institutional Repository at Imperial College London

ERIC Educational Resources Information Center

Afshari, Fereshteh; Jones, Richard

2007-01-01

Purpose: This paper aims to demonstrate how a highly integrated approach to repository development and deployment can be beneficial in producing a successful archive. Design/methodology/approach: Imperial College London undertook a significant specifications process to gather and formalise requirements for its repository system. This was done…

Enthalpies of formation of polyhalite: A mineral relevant to salt repository

DOE PAGES

Guo, Xiaofeng; Xu, Hongwu

2017-06-02

Polyhalite is an important coexisting mineral with halite in salt repositories for nuclear waste disposal, such as Waste Isolation Pilot Plant (WIPP) in Carlsbad, New Mexico. The thermal stability of this mineral is a key knowledge in evaluating the integrity of a salt repository in the long term, as water may release due to thermal decomposition of polyhalite. Previous studies on structural evolution of polyhalite at elevated temperatures laid the basis for detailed calorimetric measurements. Using high-temperature oxide-melt drop-solution calorimetry at 975 K with sodium molybdate as the solvent, we have determined the standard enthalpies of formation from constituent sulfatesmore » (ΔH° f,sul), oxides (ΔH° f,ox) and elements (ΔH° f,ele) of a polyhalite sample with the composition of K 2Ca 2Mg(SO 4) 4·1.95H 2O from the Salado formation at the WIPP site. The obtained results are: ΔH° f,sul = -152.5 ± 5.3 kJ/mol, ΔH° f,ox = -1926.1 ± 10.5 kJ/mol, and ΔH° f,ele = -6301.2 ± 9.9 kJ/mol. Furthermore, based on the estimated formation entropies of polyhalite, its standard Gibbs free energy of formation has been derived to be in the range of -5715.3 ± 9.9 kJ/mol to -5739.3 ± 9.9 kJ/mol. In conclusion, these determined thermodynamic properties provide fundamental parameters for modeling the stability behavior of polyhalite in salt repositories.« less

Citing a Data Repository: A Case Study of the Protein Data Bank.

PubMed

Huang, Yi-Hung; Rose, Peter W; Hsu, Chun-Nan

2015-01-01

The Protein Data Bank (PDB) is the worldwide repository of 3D structures of proteins, nucleic acids and complex assemblies. The PDB's large corpus of data (> 100,000 structures) and related citations provide a well-organized and extensive test set for developing and understanding data citation and access metrics. In this paper, we present a systematic investigation of how authors cite PDB as a data repository. We describe a novel metric based on information cascade constructed by exploring the citation network to measure influence between competing works and apply that to analyze different data citation practices to PDB. Based on this new metric, we found that the original publication of RCSB PDB in the year 2000 continues to attract most citations though many follow-up updates were published. None of these follow-up publications by members of the wwPDB organization can compete with the original publication in terms of citations and influence. Meanwhile, authors increasingly choose to use URLs of PDB in the text instead of citing PDB papers, leading to disruption of the growth of the literature citations. A comparison of data usage statistics and paper citations shows that PDB Web access is highly correlated with URL mentions in the text. The results reveal the trend of how authors cite a biomedical data repository and may provide useful insight of how to measure the impact of a data repository.

17 CFR 49.19 - Core principles applicable to registered swap data repositories.

Code of Federal Regulations, 2013 CFR

2013-04-01

... registered swap data repositories. 49.19 Section 49.19 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION SWAP DATA REPOSITORIES § 49.19 Core principles applicable to registered swap data repositories. (a) Compliance with core principles. To be registered, and maintain registration, a swap data...

17 CFR 49.19 - Core principles applicable to registered swap data repositories.

Code of Federal Regulations, 2012 CFR

2012-04-01

... registered swap data repositories. 49.19 Section 49.19 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION SWAP DATA REPOSITORIES § 49.19 Core principles applicable to registered swap data repositories. (a) Compliance with Core Principles. To be registered, and maintain registration, a swap data...

Electrochemical behavior of Alloy 22 and friction type rock bolt

NASA Astrophysics Data System (ADS)

Rahman, Md Sazzadur

Alloy 22 (Ni-22Cr-13Mo-3Fe-3W) is a candidate alloy for the outer shell of spent nuclear materials storage containers in the Yucca Mountain High Level Nuclear Waste Repository because of its excellent corrosion resistance. The nuclear waste container is cylindrical in shape and the end caps are welded. Typically, Alloy 22 retains the high temperature single phase cubic structure near room temperature, but topologically close packed (TCP) phases such as mu, P, sigma etc. and Cr rich carbides can form during thermal aging and welding. Rock bolts that are used for reinforcing subsurface tunnels are generally made of carbon or low alloy steels; these are being used in the nuclear repository tunnel. The corrosion behavior of these rock bolts have not been systematically evaluated under the environmental conditions of the repository. The ground waters at the Yucca Mountain (YM) repository permeate through the pores of the rock mass, and have propensity to corrode the rock bolts and waste package container. The environmental (aerated and deaerated) conditions influence the rate of corrosion in these material; these have not been systematically evaluated yet under the repository environment. In this study, the corrosion behavior of Alloy 22 and a friction type rock bolts was investigated as a function of temperature and concentration in complex multi-ionic electrolytes. Simulated electrolyte of YM ground water found in the repository environment was made in different concentrations (1X, 10X, and 100X). The interaction of simulated electrolytes in aerated and deaerated condition with Alloy 22 and low alloy steel of friction type rock bolt (split tapered cylinder type commercial design) has been investigated. Polarization resistance method was used to measure the corrosion rates. We found that the corrosion rate of Alloy 22 was higher in the deaerated electrolyte as compared to the aerated. The presence of oxygen in the electrolyte during aeration is conducive to formation

National Aeronautics and Space Administration Biological Specimen Repository

NASA Technical Reports Server (NTRS)

McMonigal, Kathleen A.; Pietrzyk, Robert a.; Johnson, Mary Anne

2008-01-01

The National Aeronautics and Space Administration Biological Specimen Repository (Repository) is a storage bank that is used to maintain biological specimens over extended periods of time and under well-controlled conditions. Samples from the International Space Station (ISS), including blood and urine, will be collected, processed and archived during the preflight, inflight and postflight phases of ISS missions. This investigation has been developed to archive biosamples for use as a resource for future space flight related research. The International Space Station (ISS) provides a platform to investigate the effects of microgravity on human physiology prior to lunar and exploration class missions. The storage of crewmember samples from many different ISS flights in a single repository will be a valuable resource with which researchers can study space flight related changes and investigate physiological markers. The development of the National Aeronautics and Space Administration Biological Specimen Repository will allow for the collection, processing, storage, maintenance, and ethical distribution of biosamples to meet goals of scientific and programmatic relevance to the space program. Archiving of the biosamples will provide future research opportunities including investigating patterns of physiological changes, analysis of components unknown at this time or analyses performed by new methodologies.

Structure, Features, and Faculty Content in ARL Member Repositories

ERIC Educational Resources Information Center

Mercer, Holly; Koenig, Jay; McGeachin, Robert B.; Tucker, Sandra L.

2011-01-01

Questions about the optimal way to present repository content to authors, submitters, and end-users, prompted this study. The authors examined, through an observation and a survey, the institutional repositories of peer institutions in the ARL for good practices related to the presentation and organization of faculty-authored institutional…

Coupled Multi-physical Simulations for the Assessment of Nuclear Waste Repository Concepts: Modeling, Software Development and Simulation

NASA Astrophysics Data System (ADS)

Massmann, J.; Nagel, T.; Bilke, L.; Böttcher, N.; Heusermann, S.; Fischer, T.; Kumar, V.; Schäfers, A.; Shao, H.; Vogel, P.; Wang, W.; Watanabe, N.; Ziefle, G.; Kolditz, O.

2016-12-01

As part of the German site selection process for a high-level nuclear waste repository, different repository concepts in the geological candidate formations rock salt, clay stone and crystalline rock are being discussed. An open assessment of these concepts using numerical simulations requires physical models capturing the individual particularities of each rock type and associated geotechnical barrier concept to a comparable level of sophistication. In a joint work group of the Helmholtz Centre for Environmental Research (UFZ) and the German Federal Institute for Geosciences and Natural Resources (BGR), scientists of the UFZ are developing and implementing multiphysical process models while BGR scientists apply them to large scale analyses. The advances in simulation methods for waste repositories are incorporated into the open-source code OpenGeoSys. Here, recent application-driven progress in this context is highlighted. A robust implementation of visco-plasticity with temperature-dependent properties into a framework for the thermo-mechanical analysis of rock salt will be shown. The model enables the simulation of heat transport along with its consequences on the elastic response as well as on primary and secondary creep or the occurrence of dilatancy in the repository near field. Transverse isotropy, non-isothermal hydraulic processes and their coupling to mechanical stresses are taken into account for the analysis of repositories in clay stone. These processes are also considered in the near field analyses of engineered barrier systems, including the swelling/shrinkage of the bentonite material. The temperature-dependent saturation evolution around the heat-emitting waste container is described by different multiphase flow formulations. For all mentioned applications, we illustrate the workflow from model development and implementation, over verification and validation, to repository-scale application simulations using methods of high performance computing.

Publishing descriptions of non-public clinical datasets: proposed guidance for researchers, repositories, editors and funding organisations.

PubMed

Hrynaszkiewicz, Iain; Khodiyar, Varsha; Hufton, Andrew L; Sansone, Susanna-Assunta

2016-01-01

Sharing of experimental clinical research data usually happens between individuals or research groups rather than via public repositories, in part due to the need to protect research participant privacy. This approach to data sharing makes it difficult to connect journal articles with their underlying datasets and is often insufficient for ensuring access to data in the long term. Voluntary data sharing services such as the Yale Open Data Access (YODA) and Clinical Study Data Request (CSDR) projects have increased accessibility to clinical datasets for secondary uses while protecting patient privacy and the legitimacy of secondary analyses but these resources are generally disconnected from journal articles-where researchers typically search for reliable information to inform future research. New scholarly journal and article types dedicated to increasing accessibility of research data have emerged in recent years and, in general, journals are developing stronger links with data repositories. There is a need for increased collaboration between journals, data repositories, researchers, funders, and voluntary data sharing services to increase the visibility and reliability of clinical research. Using the journal Scientific Data as a case study, we propose and show examples of changes to the format and peer-review process for journal articles to more robustly link them to data that are only available on request. We also propose additional features for data repositories to better accommodate non-public clinical datasets, including Data Use Agreements (DUAs).

Availability and Accessibility in an Open Access Institutional Repository: A Case Study

ERIC Educational Resources Information Center

Lee, Jongwook; Burnett, Gary; Vandegrift, Micah; Baeg, Jung Hoon; Morris, Richard

2015-01-01

Introduction: This study explores the extent to which an institutional repository makes papers available and accessible on the open Web by using 170 journal articles housed in DigiNole Commons, the institutional repository at Florida State University. Method: To analyse the repository's impact on availability and accessibility, we conducted…

Convection and thermal radiation analytical models applicable to a nuclear waste repository room

DOE Office of Scientific and Technical Information (OSTI.GOV)

Davis, B.W.

1979-01-17

Time-dependent temperature distributions in a deep geologic nuclear waste repository have a direct impact on the physical integrity of the emplaced canisters and on the design of retrievability options. This report (1) identifies the thermodynamic properties and physical parameters of three convection regimes - forced, natural, and mixed; (2) defines the convection correlations applicable to calculating heat flow in a ventilated (forced-air) and in a nonventilated nuclear waste repository room; and (3) delineates a computer code that (a) computes and compares the floor-to-ceiling heat flow by convection and radiation, and (b) determines the nonlinear equivalent conductivity table for a repositorymore » room. (The tables permit the use of the ADINAT code to model surface-to-surface radiation and the TRUMP code to employ two different emissivity properties when modeling radiation exchange between the surface of two different materials.) The analysis shows that thermal radiation dominates heat flow modes in a nuclear waste repository room.« less

Digital Libraries and Repositories in India: An Evaluative Study

ERIC Educational Resources Information Center

Mittal, Rekha; Mahesh, G.

2008-01-01

Purpose: The purpose of this research is to identify and evaluate the collections within digital libraries and repositories in India available in the public domain. Design/methodology/approach: The digital libraries and repositories were identified through a study of the literature, as well as internet searching and browsing. The resulting digital…

History, Context, and Policies of a Learning Object Repository

ERIC Educational Resources Information Center

Simpson, Steven Marshall

2016-01-01

Learning object repositories, a form of digital libraries, are robust systems that provide educators new ways to search for educational resources, collaborate with peers, and provide instruction to students in unique and varied ways. This study examines a learning object repository created by a large suburban school district to increase teaching…

NUTRITION w/Repository

NASA Image and Video Library

2009-06-06

ISS020-E-007566 (6 June 2009) --- European Space Agency astronaut Frank De Winne, Expedition 20 flight engineer, prepares to put samples in the Minus Eighty Laboratory Freezer for ISS (MELFI) in the Kibo laboratory of the International Space Station. Samples were taken as part of the Nutritional Status Assessment (Nutrition) with Repository experiment, a study done by NASA to date of human physiologic changes during long-duration spaceflight.

77 FR 26709 - Swap Data Repositories: Interpretative Statement Regarding the Confidentiality and...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-07

... COMMODITY FUTURES TRADING COMMISSION 17 CFR Part 49 RIN 3038-AD83 Swap Data Repositories... data repositories (``SDRs'').SDRs are new registered entities created by section 728 of the Dodd-Frank... Act amends section 1a of the CEA to add a definition of the term ``swap data repository.'' Pursuant to...

The Pediatric Imaging, Neurocognition, and Genetics (PING) Data Repository.

PubMed

Jernigan, Terry L; Brown, Timothy T; Hagler, Donald J; Akshoomoff, Natacha; Bartsch, Hauke; Newman, Erik; Thompson, Wesley K; Bloss, Cinnamon S; Murray, Sarah S; Schork, Nicholas; Kennedy, David N; Kuperman, Joshua M; McCabe, Connor; Chung, Yoonho; Libiger, Ondrej; Maddox, Melanie; Casey, B J; Chang, Linda; Ernst, Thomas M; Frazier, Jean A; Gruen, Jeffrey R; Sowell, Elizabeth R; Kenet, Tal; Kaufmann, Walter E; Mostofsky, Stewart; Amaral, David G; Dale, Anders M

2016-01-01

The main objective of the multi-site Pediatric Imaging, Neurocognition, and Genetics (PING) study was to create a large repository of standardized measurements of behavioral and imaging phenotypes accompanied by whole genome genotyping acquired from typically-developing children varying widely in age (3 to 20 years). This cross-sectional study produced sharable data from 1493 children, and these data have been described in several publications focusing on brain and cognitive development. Researchers may gain access to these data by applying for an account on the PING portal and filing a data use agreement. Here we describe the recruiting and screening of the children and give a brief overview of the assessments performed, the imaging methods applied, the genetic data produced, and the numbers of cases for whom different data types are available. We also cite sources of more detailed information about the methods and data. Finally we describe the procedures for accessing the data and for using the PING data exploration portal. Copyright © 2015 Elsevier Inc. All rights reserved.

Can Data Repositories Help Find Effective Treatments for Complex Diseases?

PubMed Central

Farber, Gregory K.

2016-01-01

There are many challenges to developing treatments for complex diseases. This review explores the question of whether it is possible to imagine a data repository that would increase the pace of understanding complex diseases sufficiently well to facilitate the development of effective treatments. First, consideration is given to the amount of data that might be needed for such a data repository and whether the existing data storage infrastructure is enough. Several successful data repositories are then examined to see if they have common characteristics. An area of science where unsuccessful attempts to develop a data infrastructure is then described to see what lessons could be learned for a data repository devoted to complex disease. Then, a variety of issues related to sharing data are discussed. In some of these areas, it is reasonably clear how to move forward. In other areas, there are significant open questions that need to be addressed by all data repositories. Using that baseline information, the question of whether data archives can be effective in understanding a complex disease is explored. The major goal of such a data archive is likely to be identifying biomarkers that define sub-populations of the disease. PMID:27018167

Trustworthy Digital Repositories: Building Trust the Old Fashion Way, EARNING IT.

NASA Astrophysics Data System (ADS)

Kinkade, D.; Chandler, C. L.; Shepherd, A.; Rauch, S.; Groman, R. C.; Wiebe, P. H.; Glover, D. M.; Allison, M. D.; Copley, N. J.; Ake, H.; York, A.

2016-12-01

There are several drivers increasing the importance of high quality data management and curation in today's research process (e.g., OSTP PARR memo, journal publishers, funders, academic and private institutions), and proper management is necessary throughout the data lifecycle to enable reuse and reproducibility of results. Many digital data repositories are capable of satisfying the basic management needs of an investigator looking to share their data (i.e., publish data in the public domain), but repository services vary greatly and not all provide mature services that facilitate discovery, access, and reuse of research data. Domain-specific repositories play a vital role in the data curation process by working closely with investigators to create robust metadata, perform first order QC, and assemble and publish research data. In addition, they may employ technologies and services that enable increased discovery, access, and long-term archive. However, smaller domain facilities operate in varying states of capacity and curation ability. Within this repository environment, individual investigators (driven by publishers, funders, or institutions) need to find trustworthy repositories for their data; and funders need to direct investigators to quality repositories to ensure return on their investment. So, how can one determine the best home for valuable research data? Metrics can be applied to varying aspects of data curation, and many credentialing organizations offer services that assess and certify the trustworthiness of a given data management facility. Unfortunately, many of these certifications can be inaccessible to a small repository in cost, time, or scope. Are there alternatives? This presentation will discuss methods and approaches used by the Biological and Chemical Oceanography Data Management Office (BCO-DMO; a domain-specific, intermediate digital data repository) to demonstrate trustworthiness in the face of a daunting accreditation landscape.

Schematic designs for penetration seals for a reference repository in bedded salt

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kelsall, P.C.; Case, J.B.; Meyer, D.

1982-11-01

The isolation of radioactive wastes in geologic repositories requires that man-made penetrations such as shafts, tunnels, or boreholes are adequately sealed. This report describes schematic seal designs for a repository in bedded salt referenced to the straitigraphy of southeastern New Mexico. The designs are presented for extensive peer review and will be updated as site-specific conceptual designs when a site for a repository in salt has been selected. The principal material used in the seal system is crushed salt obtained from excavating the repository. It is anticipated that crushed salt will consolidate as the repository rooms creep close to themore » degree that mechanical and hydrologic properties will eventually match those of undisturbed, intact salt. For southeastern New Mexico salt, analyses indicate that this process will require approximately 1000 years for a seal located at the base of one of the repository shafts (where there is little increase in temperature due to waste emplacement) and approximately 400 years for a seal located in an access tunnel within the repository. Bulkheads composed of contrete or salt bricks are also included in the seal system as components which will have low permeability during the period required for salt consolidation.« less

Decision Tree Repository and Rule Set Based Mingjiang River Estuarine Wetlands Classifaction

NASA Astrophysics Data System (ADS)

Zhang, W.; Li, X.; Xiao, W.

2018-05-01

The increasing urbanization and industrialization have led to wetland losses in estuarine area of Mingjiang River over past three decades. There has been increasing attention given to produce wetland inventories using remote sensing and GIS technology. Due to inconsistency training site and training sample, traditionally pixel-based image classification methods can't achieve a comparable result within different organizations. Meanwhile, object-oriented image classification technique shows grate potential to solve this problem and Landsat moderate resolution remote sensing images are widely used to fulfill this requirement. Firstly, the standardized atmospheric correct, spectrally high fidelity texture feature enhancement was conducted before implementing the object-oriented wetland classification method in eCognition. Secondly, we performed the multi-scale segmentation procedure, taking the scale, hue, shape, compactness and smoothness of the image into account to get the appropriate parameters, using the top and down region merge algorithm from single pixel level, the optimal texture segmentation scale for different types of features is confirmed. Then, the segmented object is used as the classification unit to calculate the spectral information such as Mean value, Maximum value, Minimum value, Brightness value and the Normalized value. The Area, length, Tightness and the Shape rule of the image object Spatial features and texture features such as Mean, Variance and Entropy of image objects are used as classification features of training samples. Based on the reference images and the sampling points of on-the-spot investigation, typical training samples are selected uniformly and randomly for each type of ground objects. The spectral, texture and spatial characteristics of each type of feature in each feature layer corresponding to the range of values are used to create the decision tree repository. Finally, with the help of high resolution reference images, the

Rolling Deck to Repository I: Designing a Database Infrastructure

NASA Astrophysics Data System (ADS)

Arko, R. A.; Miller, S. P.; Chandler, C. L.; Ferrini, V. L.; O'Hara, S. H.

2008-12-01

navigation and routine underway data. Based on discussion with ship operators and data managers at a workgroup meeting in September 2008, we anticipate that a subset of underway data could be delivered from ships to the central repository in near- realtime - enabling the integrated display of ship tracks at a public Web portal, for example - and a full data package could be delivered post-cruise by network transfer or disk shipment. Once ashore, data sets could be distributed to assembly centers such as the Shipboard Automated Meteorological and Oceanographic System (SAMOS) for routine processing, quality assessment, and synthesis efforts - as well as transmitted to national data centers such as NODC and NGDC for permanent archival. 3. Deployment and testing of a basic suite of Web services to make cruise summaries, vessel profiles, event logs, and navigation data easily available. A standard set of catalog records, maps, and navigation features will be published via the Open Archives Initiative (OAI) and Open Geospatial Consortium (OGC) protocols, which can then be harvested by partner data centers and/or embedded in client applications.

Building a diabetes screening population data repository using electronic medical records.

PubMed

Tuan, Wen-Jan; Sheehy, Ann M; Smith, Maureen A

2011-05-01

There has been a rapid advancement of information technology in the area of clinical and population health data management since 2000. However, with the fast growth of electronic medical records (EMRs) and the increasing complexity of information systems, it has become challenging for researchers to effectively access, locate, extract, and analyze information critical to their research. This article introduces an outpatient encounter data framework designed to construct an EMR-based population data repository for diabetes screening research. The outpatient encounter data framework is developed on a hybrid data structure of entity-attribute-value models, dimensional models, and relational models. This design preserves a small number of subject-specific tables essential to key clinical constructs in the data repository. It enables atomic information to be maintained in a transparent and meaningful way to researchers and health care practitioners who need to access data and still achieve the same performance level as conventional data warehouse models. A six-layer information processing strategy is developed to extract and transform EMRs to the research data repository. The data structure also complies with both Health Insurance Portability and Accountability Act regulations and the institutional review board's requirements. Although developed for diabetes screening research, the design of the outpatient encounter data framework is suitable for other types of health service research. It may also provide organizations a tool to improve health care quality and efficiency, consistent with the "meaningful use" objectives of the Health Information Technology for Economic and Clinical Health Act. © 2011 Diabetes Technology Society.

The Waste Isolation Pilot Plant transuranic waste repository: A sleeping beauty

DOE Office of Scientific and Technical Information (OSTI.GOV)

Eriksson, L.G.

On May 13, 1998, crowning a 24-year United States Department of Energy effort, the US Environmental Protection Agency certified that the deep geological repository for safe disposal of long-lived, transuranic radioactive waste proposed by the DOE at the Waste Isolation Pilot Plant site in New Mexico complied with all applicable environmental radiation protection standards and compliance criteria. Pursuant to the applicable law, the WIPP Land Withdrawal Act of 1992, as amended in 1997, at the decision of the secretary of energy, the WIPP repository could open 30 calendar days after receiving the EPA certification. The secretary of energy announced Maymore » 13, 1998, that he intended to open the WIPP TRUW repository by June 14, 1998. However, at the end of 1998, the opening of the WIPP TRUW repository remains hostage to time-consuming, hazardous-waste-permitting procedures by the state of New Mexico Environment Department and two legal actions. Based on the EPA-verified high safety and the demonstrated risk reduction to both current and future generations offered by the WIPP TRUW repository, it is concluded that the WIPP TRUW repository is a sleeping beauty that will awake, perhaps in stages, and begin its important mission in 1999.« less

Creating Complex Repository Collections, Such as Journals, with Manakin

ERIC Educational Resources Information Center

Koenig, Jack; Mikeal, Adam

2010-01-01

Purpose: The purpose of this paper is to report on a devised method of collection organisation within a DSpace repository using a Manakin theme and descriptive metadata. Design/methodology/approach: Using a Manakin theme, a user interface for a repository collection containing the contents of a serial was created to divide the collection into…

Modeling transient heat transfer in nuclear waste repositories.

PubMed

Yang, Shaw-Yang; Yeh, Hund-Der

2009-09-30

The heat of high-level nuclear waste may be generated and released from a canister at final disposal sites. The waste heat may affect the engineering properties of waste canisters, buffers, and backfill material in the emplacement tunnel and the host rock. This study addresses the problem of the heat generated from the waste canister and analyzes the heat distribution between the buffer and the host rock, which is considered as a radial two-layer heat flux problem. A conceptual model is first constructed for the heat conduction in a nuclear waste repository and then mathematical equations are formulated for modeling heat flow distribution at repository sites. The Laplace transforms are employed to develop a solution for the temperature distributions in the buffer and the host rock in the Laplace domain, which is numerically inverted to the time-domain solution using the modified Crump method. The transient temperature distributions for both the single- and multi-borehole cases are simulated in the hypothetical geological repositories of nuclear waste. The results show that the temperature distributions in the thermal field are significantly affected by the decay heat of the waste canister, the thermal properties of the buffer and the host rock, the disposal spacing, and the thickness of the host rock at a nuclear waste repository.

DataONE: Gateway to Earth and Environmental Data Repositories

NASA Astrophysics Data System (ADS)

Koskela, R.; Michener, W. K.; Vieglais, D.; Budden, A. E.

2017-12-01

DataONE (Data Observation Network for Earth) is a National Science Foundation DataNet project that enables universal access to data and also facilitates researchers in fulfilling their need for data management and in providing secure and permanent access to their data. DataONE offers the scientific community a suite of tools and training materials that cover all aspects of the data life cycle from data collection, to management, analysis and publication. Data repositories affiliated with DataONE are referred to as Member Nodes and represent large regional, national and international research networks, agencies, and other institutions. As part of the DataONE Federation, the repositories gain access to a range of value-added services to support their users. These services include usage tracking and reporting, content replication, and the ability to register the services created by the repository. In addition, DataONE and the California Digital Library manage ONEShare, a repository that accepts content submitted through Dash, a platform allowing researchers to easily describe, deposit and share their research data.

A laboratory validation study of the time-lapse oscillatory pumping test for leakage detection in geological repositories

NASA Astrophysics Data System (ADS)

Sun, Alexander Y.; Lu, Jiemin; Islam, Akand

2017-05-01

Geologic repositories are extensively used for disposing byproducts in mineral and energy industries. The safety and reliability of these repositories are a primary concern to environmental regulators and the public. Time-lapse oscillatory pumping test (OPT) has been introduced recently as a pressure-based technique for detecting potential leakage in geologic repositories. By routinely conducting OPT at a number of pulsing frequencies, an operator may identify the potential repository anomalies in the frequency domain, alleviating the ambiguity caused by reservoir noise and improving the signal-to-noise ratio. Building on previous theoretical and field studies, this work performed a series of laboratory experiments to validate the concept of time-lapse OPT using a custom made, stainless steel tank under relatively high pressures. The experimental configuration simulates a miniature geologic storage repository consisting of three layers (i.e., injection zone, caprock, and above-zone aquifer). Results show that leakage in the injection zone led to deviations in the power spectrum of observed pressure data, and the amplitude of which also increases with decreasing pulsing frequencies. The experimental results are further analyzed by developing a 3D flow model, using which the model parameters are estimated through frequency domain inversion.

Citing a Data Repository: A Case Study of the Protein Data Bank

PubMed Central

Huang, Yi-Hung; Rose, Peter W.; Hsu, Chun-Nan

2015-01-01

The Protein Data Bank (PDB) is the worldwide repository of 3D structures of proteins, nucleic acids and complex assemblies. The PDB’s large corpus of data (> 100,000 structures) and related citations provide a well-organized and extensive test set for developing and understanding data citation and access metrics. In this paper, we present a systematic investigation of how authors cite PDB as a data repository. We describe a novel metric based on information cascade constructed by exploring the citation network to measure influence between competing works and apply that to analyze different data citation practices to PDB. Based on this new metric, we found that the original publication of RCSB PDB in the year 2000 continues to attract most citations though many follow-up updates were published. None of these follow-up publications by members of the wwPDB organization can compete with the original publication in terms of citations and influence. Meanwhile, authors increasingly choose to use URLs of PDB in the text instead of citing PDB papers, leading to disruption of the growth of the literature citations. A comparison of data usage statistics and paper citations shows that PDB Web access is highly correlated with URL mentions in the text. The results reveal the trend of how authors cite a biomedical data repository and may provide useful insight of how to measure the impact of a data repository. PMID:26317409

My Three Wishes for Digital Repositories. Building Digital Libraries

ERIC Educational Resources Information Center

Huwe, Terence K.

2005-01-01

In this column on digital repository management, the author defines three areas within the sphere of digital repositories that need work. The first two pertain to information architecture, while the last one pertains to taking action. The author's first "wish" is for top-notch library Web sites that act as a gateway to any sphere of knowledge. He…

Object linking in repositories

NASA Technical Reports Server (NTRS)

Eichmann, David (Editor); Beck, Jon; Atkins, John; Bailey, Bill

1992-01-01

This topic is covered in three sections. The first section explores some of the architectural ramifications of extending the Eichmann/Atkins lattice-based classification scheme to encompass the assets of the full life cycle of software development. A model is considered that provides explicit links between objects in addition to the edges connecting classification vertices in the standard lattice. The second section gives a description of the efforts to implement the repository architecture using a commercially available object-oriented database management system. Some of the features of this implementation are described, and some of the next steps to be taken to produce a working prototype of the repository are pointed out. In the final section, it is argued that design and instantiation of reusable components have competing criteria (design-for-reuse strives for generality, design-with-reuse strives for specificity) and that providing mechanisms for each can be complementary rather than antagonistic. In particular, it is demonstrated how program slicing techniques can be applied to customization of reusable components.

Metadata management and semantics in microarray repositories.

PubMed

Kocabaş, F; Can, T; Baykal, N

2011-12-01

The number of microarray and other high-throughput experiments on primary repositories keeps increasing as do the size and complexity of the results in response to biomedical investigations. Initiatives have been started on standardization of content, object model, exchange format and ontology. However, there are backlogs and inability to exchange data between microarray repositories, which indicate that there is a great need for a standard format and data management. We have introduced a metadata framework that includes a metadata card and semantic nets that make experimental results visible, understandable and usable. These are encoded in syntax encoding schemes and represented in RDF (Resource Description Frame-word), can be integrated with other metadata cards and semantic nets, and can be exchanged, shared and queried. We demonstrated the performance and potential benefits through a case study on a selected microarray repository. We concluded that the backlogs can be reduced and that exchange of information and asking of knowledge discovery questions can become possible with the use of this metadata framework.

10 CFR 63.112 - Requirements for preclosure safety analysis of the geologic repository operations area.

Code of Federal Regulations, 2010 CFR

2010-01-01

... geologic repository operations area. 63.112 Section 63.112 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC REPOSITORY AT YUCCA MOUNTAIN, NEVADA Technical... repository operations area. The preclosure safety analysis of the geologic repository operations area must...

Scenario Analysis for the Safety Assessment of Nuclear Waste Repositories: A Critical Review.

PubMed

Tosoni, Edoardo; Salo, Ahti; Zio, Enrico

2018-04-01

A major challenge in scenario analysis for the safety assessment of nuclear waste repositories pertains to the comprehensiveness of the set of scenarios selected for assessing the safety of the repository. Motivated by this challenge, we discuss the aspects of scenario analysis relevant to comprehensiveness. Specifically, we note that (1) it is necessary to make it clear why scenarios usually focus on a restricted set of features, events, and processes; (2) there is not yet consensus on the interpretation of comprehensiveness for guiding the generation of scenarios; and (3) there is a need for sound approaches to the treatment of epistemic uncertainties. © 2017 Society for Risk Analysis.

New directions in medical e-curricula and the use of digital repositories.

PubMed

Fleiszer, David M; Posel, Nancy H; Steacy, Sean P

2004-03-01

Medical educators involved in the growth of multimedia-enhanced e-curricula are increasingly aware of the need for digital repositories to catalogue, store and ensure access to learning objects that are integrated within their online material. The experience at the Faculty of Medicine at McGill University during initial development of a mainstream electronic curriculum reflects this growing recognition that repositories can facilitate the development of a more comprehensive as well as effective electronic curricula. Also, digital repositories can help to ensure efficient utilization of resources through the use, re-use, and reprocessing of multimedia learning, addressing the potential for collaboration among repositories and increasing available material exponentially. The authors review different approaches to the development of a digital repository application, as well as global and specific issues that should be examined in the initial requirements definition and development phase, to ensure current initiatives meet long-term requirements. Often, decisions regarding creation of e-curricula and associated digital repositories are left to interested faculty and their individual development teams. However, the development of an e-curricula and digital repository is not predominantly a technical exercise, but rather one that affects global pedagogical strategies and curricular content and involves a commitment of large-scale resources. Outcomes of these decisions can have long-term consequences and as such, should involve faculty at the highest levels including the dean.

10 CFR 63.113 - Performance objectives for the geologic repository after permanent closure.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Performance objectives for the geologic repository after...-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC REPOSITORY AT YUCCA MOUNTAIN, NEVADA Technical Criteria Postclosure Performance Objectives § 63.113 Performance objectives for the geologic repository after permanent...

Can data repositories help find effective treatments for complex diseases?

PubMed

Farber, Gregory K

2017-05-01

There are many challenges to developing treatments for complex diseases. This review explores the question of whether it is possible to imagine a data repository that would increase the pace of understanding complex diseases sufficiently well to facilitate the development of effective treatments. First, consideration is given to the amount of data that might be needed for such a data repository and whether the existing data storage infrastructure is enough. Several successful data repositories are then examined to see if they have common characteristics. An area of science where unsuccessful attempts to develop a data infrastructure is then described to see what lessons could be learned for a data repository devoted to complex disease. Then, a variety of issues related to sharing data are discussed. In some of these areas, it is reasonably clear how to move forward. In other areas, there are significant open questions that need to be addressed by all data repositories. Using that baseline information, the question of whether data archives can be effective in understanding a complex disease is explored. The major goal of such a data archive is likely to be identifying biomarkers that define sub-populations of the disease. Published by Elsevier Ltd.

3D structure of a complex of transform basins from gravity data, a case study from the central Dead Sea fault

NASA Astrophysics Data System (ADS)

Rosenthal, Michal; Schattner, Uri; Ben-Avraham, Zvi

2017-04-01

The Kinneret-Bet She'an (KBS) basin complex comprises the Sea of Galilee, Kinarot, and Bet She'an sub-basins. The complex developed at the intersection between two major tectonic boundaries: the Oligo-Miocene Azraq-Sirhan failed rift, that later developed into the southern Galilee basins and Carmel-Gilboa fault system; and the Dead Sea fault (DSF) plate boundary that developed since the Miocene. Despite numerous studies, KBS still remains one of the enigmatic basin complexes. Its structure, stratigraphy and development are vaguely understood - both inside the basin and in correlation with its surroundings. Our study presents a new and comprehensive 3D model for the structure of KBS complex. It is based on all available gravity measurements, adopted from the national gravity database, and new gravity measurements, collected in cooperation with the Geological Survey of Israel and funded by the Ministry of National Infrastructure, Energy and Water Resources. The gravity data were integrated with constraints from boreholes, surface geology, seismic surveys, potential field studies and teleseismic tomography. The dense distribution of gravity data [1] provides suitable coverage for modeling the deep structure in three dimensions. The model details the spatial distribution, depth, thickness and density of the following regional units within the KBS complex and across its surroundings: upper crust, pre-Senonian sediments, Senonian and Cenozoic sediments, Miocene volcanics, Pliocene and Quaternary volcanics. Additional local units include salt, gabbro and pyroclasts. Results indicate that the KBS complex comprises two sub-basins separated by a structural saddle: Kinneret-Kinarot ( 6-7 km deep, 45 km long) and Bet She'an ( 4 km deep, 10 km long) sub-basin. A 500 m thick layer of Miocene volcanics appears across the Bet She'an sub-basin, yet missing from the Kinneret-Kinarot sub-basin. Between the basins Zemah-1 borehole penetrated a salt unit. The model indicates that this

A metadata-driven approach to data repository design.

PubMed

Harvey, Matthew J; McLean, Andrew; Rzepa, Henry S

2017-01-01

The design and use of a metadata-driven data repository for research data management is described. Metadata is collected automatically during the submission process whenever possible and is registered with DataCite in accordance with their current metadata schema, in exchange for a persistent digital object identifier. Two examples of data preview are illustrated, including the demonstration of a method for integration with commercial software that confers rich domain-specific data analytics without introducing customisation into the repository itself.

National Date Palm Germplasm Repository

USDA-ARS?s Scientific Manuscript database

The National Clonal Germplasm Repository for Citrus & Dates (NCGRCD), located in Riverside, California USA, is a project of the Agricultural Research Service (ARS) of the United States Department of Agriculture (USDA). The NCGRCD maintains a collection of germplasm of date palm (Phoneix dactylifera ...

Cancer Epidemiology Data Repository (CEDR)

Cancer.gov

In an effort to broaden access and facilitate efficient data sharing, the Epidemiology and Genomics Research Program (EGRP) has created the Cancer Epidemiology Data Repository (CEDR), a centralized, controlled-access database, where Investigators can deposit individual-level de-identified observational cancer datasets.

Repository contributions to Rubus research

USDA-ARS?s Scientific Manuscript database

The USDA National Plant Germplasm System is a nation-wide source for global genetic resources. The National Clonal Germplasm Repository (NCGR) in Corvallis, OR, maintains crops and crop wild relatives for the Willamette Valley including pear, raspberry and blackberry, strawberry, blueberry, gooseber...

Mining Hierarchies and Similarity Clusters from Value Set Repositories.

PubMed

Peterson, Kevin J; Jiang, Guoqian; Brue, Scott M; Shen, Feichen; Liu, Hongfang

2017-01-01

A value set is a collection of permissible values used to describe a specific conceptual domain for a given purpose. By helping to establish a shared semantic understanding across use cases, these artifacts are important enablers of interoperability and data standardization. As the size of repositories cataloging these value sets expand, knowledge management challenges become more pronounced. Specifically, discovering value sets applicable to a given use case may be challenging in a large repository. In this study, we describe methods to extract implicit relationships between value sets, and utilize these relationships to overlay organizational structure onto value set repositories. We successfully extract two different structurings, hierarchy and clustering, and show how tooling can leverage these structures to enable more effective value set discovery.

NUTRITION w/Repository

NASA Image and Video Library

2009-06-06

ISS020-E-007577 (6 June 2009) --- European Space Agency astronaut Frank De Winne, Expedition 20 flight engineer, returns a dewar tray to the Minus Eighty Laboratory Freezer for ISS (MELFI) after inserting biological samples into the trays in the Kibo laboratory of the International Space Station. Samples were taken as part of the Nutritional Status Assessment (Nutrition) with Repository experiment, a study done by NASA to date of human physiologic changes during long-duration spaceflight.

NUTRITION w/Repository

NASA Image and Video Library

2009-06-06

ISS020-E-007603 (7 June 2009) --- European Space Agency astronaut Frank De Winne, Expedition 20 flight engineer, removes a dewar tray from the Minus Eighty Laboratory Freezer for ISS (MELFI) in order to insert biological samples into the trays in the Kibo laboratory of the International Space Station. Samples were taken as part of the Nutritional Status Assessment (Nutrition) with Repository experiment, a study done by NASA to date of human physiologic changes during long-duration spaceflight.

The environmental constraint needs for design improvements to the Saligny I/LLW-repository near Cernavoda NPP

DOE Office of Scientific and Technical Information (OSTI.GOV)

Barariu, Gheorghe

2007-07-01

The paper presents the new perspectives on the development of the L/ILW Final Repository Project which will be built near Cernavoda NPP. The Repository is designed to satisfy the main performance objectives in accordance to IAEA recommendation. Starting in October 1996, Romania became a country with an operating nuclear power plant. Reactor 2 reached the criticality on May 6, 2007 and it will be put in commercial operation in September 2007. The Ministry of Economy and Finance has decided to proceed with the commissioning of Units 3 and 4 of Cernavoda NPP till 2014. The Strategy for radioactive waste managementmore » was elaborated by National Agency for Radioactive Waste (ANDRAD), the jurisdictional authority for definitive disposal and the coordination of nuclear spent fuel and radioactive waste management (Order 844/2004) with attributions established by Governmental Decision (GO) 31/2006. The Strategy specifies the commissioning of the Saligny L/IL Radwaste Repository near Cernavoda NPP in 2014. When designing the L/IL Radwaste Repository, the following prerequisites have been taken into account: 1) Cernavoda NPP will be equipped with 4 Candu 6 units. 2) National Legislation in radwaste management will be reviewed and/or completed to harmonize with UE standards 3) The selected site is now in process of confirmation after a comprehensive set of interdisciplinary investigations. (author)« less

Migration of the Gaudi and LHCb software repositories from CVS to Subversion

NASA Astrophysics Data System (ADS)

Clemencic, M.; Degaudenzi, H.; LHCb Collaboration

2011-12-01

A common code repository is of primary importance in a distributed development environment such as large HEP experiments. CVS (Concurrent Versions System) has been used in the past years at CERN for the hosting of shared software repositories, among which were the repositories for the Gaudi Framework and the LHCb software projects. Many developers around the world produced alternative systems to share code and revisions among several developers, mainly to overcome the limitations in CVS, and CERN has recently started a new service for code hosting based on the version control system Subversion. The differences between CVS and Subversion and the way the code was organized in Gaudi and LHCb CVS repositories required careful study and planning of the migration. Special care was used to define the organization of the new Subversion repository. To avoid as much as possible disruption in the development cycle, the migration has been gradual with the help of tools developed explicitly to hide the differences between the two systems. The principles guiding the migration steps, the organization of the Subversion repository and the tools developed will be presented, as well as the problems encountered both from the librarian and the user points of view.

Environmental assessment: Reference repository location, Hanford site, Washington

DOE Office of Scientific and Technical Information (OSTI.GOV)

none,

1986-05-01

In February 1983, the US Department of Energy (DOE) identified a reference repository location at the Hanford Site in Washington as one of the nine potentially acceptable sites for a mined geologic repository for spent nuclear fuel and high-level radioactive waste. The site is in the Columbia Plateau, which is one of five distinct geohydrologic settings considered for the first repository. To determine their suitability, the Hanford Site and the eight other potentially acceptable sites have been evaluated in accordance with the DOE's General Guidelines for the Recommendation of Sites for the Nuclear Waste Repositories. These evaluations were reported inmore » draft environmental assessments (EAs), which were issued for public review and comment. After considering the comments received on the draft EAs, the DOE prepared the final EAs. On the basis of the evaluations reported in this EA, the DOE has found that the Hanford site is not disqualified under the guidelines. The DOE has also found that it is suitable for site characterization because the evidence does not support a conclusion that the site will not be able to meet each of the qualifying conditions specified in the guidelines. On the basis of these findings, the DOE is nominating the Hanford site as one of five sites suitable for characterization.« less

Modeling of irradiated graphite (14)C transfer through engineered barriers of a generic geological repository in crystalline rocks.

PubMed

Poskas, Povilas; Grigaliuniene, Dalia; Narkuniene, Asta; Kilda, Raimondas; Justinavicius, Darius

2016-11-01

There are two RBMK-1500 type graphite moderated reactors at the Ignalina nuclear power plant in Lithuania, and they are under decommissioning now. The graphite cannot be disposed of in a near surface repository, because of large amounts of (14)C. Therefore, disposal of the graphite in a geological repository is a reasonable solution. This study presents evaluation of the (14)C transfer by the groundwater pathway into the geosphere from the irradiated graphite in a generic geological repository in crystalline rocks and demonstration of the role of the different components of the engineered barrier system by performing local sensitivity analysis. The speciation of the released (14)C into organic and inorganic compounds as well as the most recent information on (14)C source term was taken into account. Two alternatives were considered in the analysis: disposal of graphite in containers with encapsulant and without it. It was evaluated that the maximal fractional flux of inorganic (14)C into the geosphere can vary from 10(-11)y(-1) (for non-encapsulated graphite) to 10(-12)y(-1) (for encapsulated graphite) while of organic (14)C it was about 10(-3)y(-1) of its inventory. Such difference demonstrates that investigations on the (14)C inventory and chemical form in which it is released are especially important. The parameter with the highest influence on the maximal flux into the geosphere for inorganic (14)C transfer was the sorption coefficient in the backfill and for organic (14)C transfer - the backfill hydraulic conductivity. Copyright © 2016 Elsevier B.V. All rights reserved.

Knowledge repositories for multiple uses

NASA Technical Reports Server (NTRS)

Williamson, Keith; Riddle, Patricia

1991-01-01

In the life cycle of a complex physical device or part, for example, the docking bay door of the Space Station, there are many uses for knowledge about the device or part. The same piece of knowledge might serve several uses. Given the quantity and complexity of the knowledge that must be stored, it is critical to maintain the knowledge in one repository, in one form. At the same time, because of quantity and complexity of knowledge that must be used in life cycle applications such as cost estimation, re-design, and diagnosis, it is critical to automate such knowledge uses. For each specific use, a knowledge base must be available and must be in a from that promotes the efficient performance of that knowledge base. However, without a single source knowledge repository, the cost of maintaining consistent knowledge between multiple knowledge bases increases dramatically; as facts and descriptions change, they must be updated in each individual knowledge base. A use-neutral representation of a hydraulic system for the F-111 aircraft was developed. The ability to derive portions of four different knowledge bases is demonstrated from this use-neutral representation: one knowledge base is for re-design of the device using a model-based reasoning problem solver; two knowledge bases, at different levels of abstraction, are for diagnosis using a model-based reasoning solver; and one knowledge base is for diagnosis using an associational reasoning problem solver. It was shown how updates issued against the single source use-neutral knowledge repository can be propagated to the underlying knowledge bases.

USAF Hearing Conservation Program, DOEHRS-HC Data Repository Annual Report: CY15

DTIC Science & Technology

2017-05-31

AFRL-SA-WP-SR-2017-0014 USAF Hearing Conservation Program, DOEHRS-HC Data Repository Annual Report: CY15 Daniel A. Williams...Conservation Program, DOEHRS-HC Data Repository Annual Report: CY15 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR...Health Readiness System-Hearing Conservation Data Repository (DOEHRS-HC DR). Major command- and installation-level reports are available quarterly

Rock and Core Repository Coming Digital

NASA Astrophysics Data System (ADS)

Maicher, Doris; Fleischer, Dirk; Czerniak, Andreas

2016-04-01

In times of whole city centres being available by a mouse click in 3D to virtually walk through, reality sometimes becomes neglected. The reality of scientific sample collections not being digitised to the essence of molecules, isotopes and electrons becomes unbelievable to the upgrowing generation of scientists. Just like any other geological institute the Helmholtz Centre for Ocean Research GEOMAR accumulated thousands of specimen. The samples, collected mainly during marine expeditions, date back as far as 1964. Today GEOMAR houses a central geological sample collection of at least 17 000 m of sediment core and more than 4 500 boxes with hard rock samples and refined sample specimen. This repository, having been dormant, missed the onset of the interconnected digital age. Physical samples without barcodes, QR codes or RFID tags need to be migrated and reconnected, urgently. In our use case, GEOMAR opted for the International Geo Sample Number IGSN as the persistent identifier. Consequentially, the software CurationDIS by smartcube GmbH as the central component of this project was selected. The software is designed to handle acquisition and administration of sample material and sample archiving in storage places. In addition, the software allows direct embedding of IGSN. We plan to adopt IGSN as a future asset, while for the initial inventory taking of our sample material, simple but unique QR codes act as "bridging identifiers" during the process. Currently we compile an overview of the broad variety of sample types and their associated data. QR-coding of the boxes of rock samples and sediment cores is near completion, delineating their location in the repository and linking a particular sample to any information available about the object. Planning is in progress to streamline the flow from receiving new samples to their curation to sharing samples and information publically. Additionally, interface planning for linkage to GEOMAR databases Ocean

A hydrogen isotope study of CO3 type carbonaceous chondrites; comparison with type 3 ordinary chondrites

NASA Technical Reports Server (NTRS)

Morse, A. D.; Newton, J.; Pillinger, C. T.

1993-01-01

Meteorites of the Ornans type 3 carbonaceous chondrites exhibit a range in degree of equilibration, attributed to differing amounts of thermal metamorphism. These differences have been used to split the CO3 chondrites into petrologic sub-types from 3.0, least equilibrated, to 3.7, being most equilibrated. This is similar to the system of assigning the type 3 ordinary chondrites into petrologic sub-types 3.0 to 3.9 based upon thermoluminescence (TL) and other properties; however, the actual range of thermal metamorphism experienced by CO3 chondrites is much less than that of the type 3 ordinary chondrites. The least equilibrated ordinary chondrites show evidence of aqueous alteration and have high D/H ratios possibly due to a deuterium-rich organic carrier. The aim of this study was to determine whether the CO3 chondrites, which have experienced similar secondary conditions to the type 3 ordinary chondrites, also contain a similar deuterium-rich carrier. To date a total of 5 CO3 meteorites, out of a set of 11 for which carbon and nitrogen isotopic data are available, have been analyzed. Ornans has not been analyzed yet, because it does not appear to fit in with the metamorphic sequence exhibited by the other CO3 chondrites; it also has an extremely high delta-D value of +2150 percent, unusual for such a comparatively equilibrated meteorite (type 3.4). Initial results indicate that the more equilibrated CO3's tend to have lower delta-D values, analogous to the higher petrologic type ordinary chondrites. However this is complicated by the effects of terrestrial weathering and the small data-set.

Online Paper Repositories and the Role of Scholarly Societies: An AERA Conference Report

ERIC Educational Resources Information Center

Educational Researcher, 2010

2010-01-01

This article examines issues faced by scholarly societies that are developing and sustaining online paper repositories. It is based on the AERA Conference on Online Paper Repositories, which focused on fundamental issues of policy and procedure important to the operations of online working paper repositories. The report and recommendations address…

PAX3 mutations and clinical characteristics in Chinese patients with Waardenburg syndrome type 1

PubMed Central

Wang, Juan; Li, Shiqiang; Xiao, Xueshan; Wang, Panfeng; Guo, Xiangming

2010-01-01

Purpose To detect paired box gene 3 (PAX3) mutations and associated phenotypes in Chinese patients with Waardenburg syndrome type 1 (WS1). Methods Five unrelated families with suspected WS1 were selected from our Genomic DNA Repository for Hereditary Eye Diseases. The coding and adjacent intronic regions of PAX3 were amplified by polymerase chain reaction and the amplicons were then analyzed by cycle sequencing. Variations detected were further evaluated in available family members as well as one hundred controls with heteroduplex-single strand conformational polymorphism (heteroduplex-SSCP) analysis and/or clone sequencing. Results Three novel and two known mutations in PAX3 were detected in five patients, respectively: c.567_586+17del (p.Asp189_Gln505delinsGluGlyGlyAlaLeuAlaGly), c.456_459dupTTCC (p.Ile154PhefsX162), c.795_800delCTGGTT (p.Trp266_Phe267del), c.799T>A (p.Phe267Ile), and c.667C>T (p.Arg223X). Two novel mutations proved to be de novo as their parents did not carry the mutations. All five patients with PAX3 mutations had dystopia canthorum and different iris color and fundi between their two eyes. However, none had white forelock, skin hypopigmentation, and deafness. Conclusions Our findings expand the frequency and spectrum of PAX3 mutations and ethnic-related phenotypes in Chinese patients with WS1. De novo mutations in PAX3 have not been reported before. PMID:20664692

PAX3 mutations and clinical characteristics in Chinese patients with Waardenburg syndrome type 1.

PubMed

Wang, Juan; Li, Shiqiang; Xiao, Xueshan; Wang, Panfeng; Guo, Xiangming; Zhang, Qingjiong

2010-06-22

To detect paired box gene 3 (PAX3) mutations and associated phenotypes in Chinese patients with Waardenburg syndrome type 1 (WS1). Five unrelated families with suspected WS1 were selected from our Genomic DNA Repository for Hereditary Eye Diseases. The coding and adjacent intronic regions of PAX3 were amplified by polymerase chain reaction and the amplicons were then analyzed by cycle sequencing. Variations detected were further evaluated in available family members as well as one hundred controls with heteroduplex-single strand conformational polymorphism (heteroduplex-SSCP) analysis and/or clone sequencing. Three novel and two known mutations in PAX3 were detected in five patients, respectively: c.567_586+17del (p.Asp189_Gln505delinsGluGlyGlyAlaLeuAlaGly), c.456_459dupTTCC (p.Ile154PhefsX162), c.795_800delCTGGTT (p.Trp266_Phe267del), c.799T>A (p.Phe267Ile), and c.667C>T (p.Arg223X). Two novel mutations proved to be de novo as their parents did not carry the mutations. All five patients with PAX3 mutations had dystopia canthorum and different iris color and fundi between their two eyes. However, none had white forelock, skin hypopigmentation, and deafness. Our findings expand the frequency and spectrum of PAX3 mutations and ethnic-related phenotypes in Chinese patients with WS1. De novo mutations in PAX3 have not been reported before.

Repository-Based Software Engineering Program: Working Program Management Plan

NASA Technical Reports Server (NTRS)

1993-01-01

Repository-Based Software Engineering Program (RBSE) is a National Aeronautics and Space Administration (NASA) sponsored program dedicated to introducing and supporting common, effective approaches to software engineering practices. The process of conceiving, designing, building, and maintaining software systems by using existing software assets that are stored in a specialized operational reuse library or repository, accessible to system designers, is the foundation of the program. In addition to operating a software repository, RBSE promotes (1) software engineering technology transfer, (2) academic and instructional support of reuse programs, (3) the use of common software engineering standards and practices, (4) software reuse technology research, and (5) interoperability between reuse libraries. This Program Management Plan (PMP) is intended to communicate program goals and objectives, describe major work areas, and define a management report and control process. This process will assist the Program Manager, University of Houston at Clear Lake (UHCL) in tracking work progress and describing major program activities to NASA management. The goal of this PMP is to make managing the RBSE program a relatively easy process that improves the work of all team members. The PMP describes work areas addressed and work efforts being accomplished by the program; however, it is not intended as a complete description of the program. Its focus is on providing management tools and management processes for monitoring, evaluating, and administering the program; and it includes schedules for charting milestones and deliveries of program products. The PMP was developed by soliciting and obtaining guidance from appropriate program participants, analyzing program management guidance, and reviewing related program management documents.

The Microbiology of Subsurface, Salt-Based Nuclear Waste Repositories: Using Microbial Ecology, Bioenergetics, and Projected Conditions to Help Predict Microbial Effects on Repository Performance

DOE Office of Scientific and Technical Information (OSTI.GOV)

Swanson, Juliet S.; Cherkouk, Andrea; Arnold, Thuro

This report summarizes the potential role of microorganisms in salt-based nuclear waste repositories using available information on the microbial ecology of hypersaline environments, the bioenergetics of survival under high ionic strength conditions, and “repository microbiology” related studies. In areas where microbial activity is in question, there may be a need to shift the research focus toward feasibility studies rather than studies that generate actual input for performance assessments. In areas where activity is not necessary to affect performance (e.g., biocolloid transport), repository-relevant data should be generated. Both approaches will lend a realistic perspective to a safety case/performance scenario that willmore » most likely underscore the conservative value of that case.« less

On-line remote monitoring of radioactive waste repositories

NASA Astrophysics Data System (ADS)

Calì, Claudio; Cosentino, Luigi; Litrico, Pietro; Pappalardo, Alfio; Scirè, Carlotta; Scirè, Sergio; Vecchio, Gianfranco; Finocchiaro, Paolo; Alfieri, Severino; Mariani, Annamaria

2014-12-01

A low-cost array of modular sensors for online monitoring of radioactive waste was developed at INFN-LNS. We implemented a new kind of gamma counter, based on Silicon PhotoMultipliers and scintillating fibers, that behaves like a cheap scintillating Geiger-Muller counter. It can be placed in shape of a fine grid around each single waste drum in a repository. Front-end electronics and an FPGA-based counting system were developed to handle the field data, also implementing data transmission, a graphical user interface and a data storage system. A test of four sensors in a real radwaste storage site was performed with promising results. Following the tests an agreement was signed between INFN and Sogin for the joint development and installation of a prototype DMNR (Detector Mesh for Nuclear Repository) system inside the Garigliano radwaste repository in Sessa Aurunca (CE, Italy). Such a development is currently under way, with the installation foreseen within 2014.

The Listening and Spoken Language Data Repository: Design and Project Overview

ERIC Educational Resources Information Center

Bradham, Tamala S.; Fonnesbeck, Christopher; Toll, Alice; Hecht, Barbara F.

2018-01-01

Purpose: The purpose of the Listening and Spoken Language Data Repository (LSL-DR) was to address a critical need for a systemwide outcome data-monitoring program for the development of listening and spoken language skills in highly specialized educational programs for children with hearing loss highlighted in Goal 3b of the 2007 Joint Committee…

Proceedings of the scientific visit on crystalline rock repository development.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mariner, Paul E.; Hardin, Ernest L.; Miksova, Jitka

2013-02-01

A scientific visit on Crystalline Rock Repository Development was held in the Czech Republic on September 24-27, 2012. The visit was hosted by the Czech Radioactive Waste Repository Authority (RAWRA), co-hosted by Sandia National Laboratories (SNL), and supported by the International Atomic Energy Agency (IAEA). The purpose of the visit was to promote technical information exchange between participants from countries engaged in the investigation and exploration of crystalline rock for the eventual construction of nuclear waste repositories. The visit was designed especially for participants of countries that have recently commenced (or recommenced) national repository programmes in crystalline host rock formations.more » Discussion topics included repository programme development, site screening and selection, site characterization, disposal concepts in crystalline host rock, regulatory frameworks, and safety assessment methodology. Interest was surveyed in establishing a %E2%80%9Cclub,%E2%80%9D the mission of which would be to identify and address the various technical challenges that confront the disposal of radioactive waste in crystalline rock environments. The idea of a second scientific visit to be held one year later in another host country received popular support. The visit concluded with a trip to the countryside south of Prague where participants were treated to a tour of the laboratory and underground facilities of the Josef Regional Underground Research Centre.« less

Preliminary safety analysis of the Baita Bihor radioactive waste repository, Romania

DOE Office of Scientific and Technical Information (OSTI.GOV)

Little, Richard; Bond, Alex; Watson, Sarah

2007-07-01

A project funded under the European Commission's Phare Programme 2002 has undertaken an in-depth analysis of the operational and post-closure safety of the Baita Bihor repository. The repository has accepted low- and some intermediate-level radioactive waste from industry, medical establishments and research activities since 1985 and the current estimate is that disposals might continue for around another 20 to 35 years. The analysis of the operational and post-closure safety of the Baita Bihor repository was carried out in two iterations, with the second iteration resulting in reduced uncertainties, largely as a result taking into account new information on the hydrologymore » and hydrogeology of the area, collected as part of the project. Impacts were evaluated for the maximum potential inventory that might be available for disposal to Baita Bihor for a number of operational and postclosure scenarios and associated conceptual models. The results showed that calculated impacts were below the relevant regulatory criteria. In light of the assessment, a number of recommendations relating to repository operation, optimisation of repository engineering and waste disposals, and environmental monitoring were made. (authors)« less

Credentialing Data Scientists: A Domain Repository Perspective

NASA Astrophysics Data System (ADS)

Lehnert, K. A.; Furukawa, H.

2015-12-01

A career in data science can have many paths: data curation, data analysis, metadata modeling - all of these in different commercial or scientific applications. Can a certification as 'data scientist' provide the guarantee that an applicant or candidate for a data science position has just the right skills? How valuable is a 'generic' certification as data scientist for an employer looking to fill a data science position? Credentials that are more specific and discipline-oriented may be more valuable to both the employer and the job candidate. One employment sector for data scientists are the data repositories that provide discipline-specific data services for science communities. Data science positions within domain repositories include a wide range of responsibilities in support of the full data life cycle - from data preservation and curation to development of data models, ontologies, and user interfaces, to development of data analysis and visualization tools to community education and outreach, and require a substantial degree of discipline-specific knowledge of scientific data acquisition and analysis workflows, data quality measures, and data cultures. Can there be certification programs for domain-specific data scientists that help build the urgently needed workforce for the repositories? The American Geophysical Union has recently started an initiative to develop a program for data science continuing education and data science professional certification for the Earth and space sciences. An Editorial Board has been charged to identify and develop curricula and content for these programs and to provide input and feedback in the implementation of the program. This presentation will report on the progress of this initiative and evaluate its utility for the needs of domain repositories in the Earth and space sciences.

Performance Assessments of Generic Nuclear Waste Repositories in Shale

NASA Astrophysics Data System (ADS)

Stein, E. R.; Sevougian, S. D.; Mariner, P. E.; Hammond, G. E.; Frederick, J.

2017-12-01

Simulations of deep geologic disposal of nuclear waste in a generic shale formation showcase Geologic Disposal Safety Assessment (GDSA) Framework, a toolkit for repository performance assessment (PA) whose capabilities include domain discretization (Cubit), multiphysics simulations (PFLOTRAN), uncertainty and sensitivity analysis (Dakota), and visualization (Paraview). GDSA Framework is used to conduct PAs of two generic repositories in shale. The first considers the disposal of 22,000 metric tons heavy metal of commercial spent nuclear fuel. The second considers disposal of defense-related spent nuclear fuel and high level waste. Each PA accounts for the thermal load and radionuclide inventory of applicable waste types, components of the engineered barrier system, and components of the natural barrier system including the host rock shale and underlying and overlying stratigraphic units. Model domains are half-symmetry, gridded with Cubit, and contain between 7 and 22 million grid cells. Grid refinement captures the detail of individual waste packages, emplacement drifts, access drifts, and shafts. Simulations are run in a high performance computing environment on as many as 2048 processes. Equations describing coupled heat and fluid flow and reactive transport are solved with PFLOTRAN, an open-source, massively parallel multiphase flow and reactive transport code. Additional simulated processes include waste package degradation, waste form dissolution, radioactive decay and ingrowth, sorption, solubility, advection, dispersion, and diffusion. Simulations are run to 106 y, and radionuclide concentrations are observed within aquifers at a point approximately 5 km downgradient of the repository. Dakota is used to sample likely ranges of input parameters including waste form and waste package degradation rates and properties of engineered and natural materials to quantify uncertainty in predicted concentrations and sensitivity to input parameters. Sandia National

Three-dimensional thermal analysis of a high-level waste repository

DOE Office of Scientific and Technical Information (OSTI.GOV)

Altenbach, T.J.

1979-04-01

The analysis used the TRUMP computer code to evaluate the thermal fields for six repository scenarios that studied the effects of room ventilation, room backfill, and repository thermal diffusivity. The results for selected nodes are presented as plots showing the effect of temperature as a function of time. 15 figures, 6 tables.

Using Linked Open Data and Semantic Integration to Search Across Geoscience Repositories

NASA Astrophysics Data System (ADS)

Mickle, A.; Raymond, L. M.; Shepherd, A.; Arko, R. A.; Carbotte, S. M.; Chandler, C. L.; Cheatham, M.; Fils, D.; Hitzler, P.; Janowicz, K.; Jones, M.; Krisnadhi, A.; Lehnert, K. A.; Narock, T.; Schildhauer, M.; Wiebe, P. H.

2014-12-01

The MBLWHOI Library is a partner in the OceanLink project, an NSF EarthCube Building Block, applying semantic technologies to enable knowledge discovery, sharing and integration. OceanLink is testing ontology design patterns that link together: two data repositories, Rolling Deck to Repository (R2R), Biological and Chemical Oceanography Data Management Office (BCO-DMO); the MBLWHOI Library Institutional Repository (IR) Woods Hole Open Access Server (WHOAS); National Science Foundation (NSF) funded awards; and American Geophysical Union (AGU) conference presentations. The Library is collaborating with scientific users, data managers, DSpace engineers, experts in ontology design patterns, and user interface developers to make WHOAS, a DSpace repository, linked open data enabled. The goal is to allow searching across repositories without any of the information providers having to change how they manage their collections. The tools developed for DSpace will be made available to the community of users. There are 257 registered DSpace repositories in the United Stated and over 1700 worldwide. Outcomes include: Integration of DSpace with OpenRDF Sesame triple store to provide SPARQL endpoint for the storage and query of RDF representation of DSpace resources, Mapping of DSpace resources to OceanLink ontology, and DSpace "data" add on to provide resolvable linked open data representation of DSpace resources.

10 CFR 60.111 - Performance of the geologic repository operations area through permanent closure.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Performance of the geologic repository operations area... OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Technical Criteria Performance Objectives § 60.111 Performance of the geologic repository operations area through permanent closure. (a...

Preliminary safety evaluation of an aircraft impact on a near-surface radioactive waste repository

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lo Frano, R.; Forasassi, G.; Pugliese, G.

2013-07-01

The aircraft impact accident has become very significant in the design of a nuclear facilities, particularly, after the tragic September 2001 event, that raised the public concern about the potential damaging effects that the impact of a large civilian airplane could bring in safety relevant structures. The aim of this study is therefore to preliminarily evaluate the global response and the structural effects induced by the impact of a military or commercial airplane (actually considered as a 'beyond design basis' event) into a near surface radioactive waste (RWs) disposal facility. The safety evaluation was carried out according to the Internationalmore » safety and design guidelines and in agreement with the stress tests requirements for the security track. To achieve the purpose, a lay out and a scheme of a possible near surface repository, like for example those of the El Cabril one, were taken into account. In order to preliminarily perform a reliable analysis of such a large-scale structure and to determine the structural effects induced by such a types of impulsive loads, a realistic, but still operable, numerical model with suitable materials characteristics was implemented by means of FEM codes. In the carried out structural analyses, the RWs repository was considered a 'robust' target, due to its thicker walls and main constitutive materials (steel and reinforced concrete). In addition to adequately represent the dynamic response of repository under crashing, relevant physical phenomena (i.e. penetration, spalling, etc.) were simulated and analysed. The preliminary assessment of the effects induced by the dynamic/impulsive loads allowed generally to verify the residual strength capability of the repository considered. The obtained preliminary results highlighted a remarkable potential to withstand the impact of military/large commercial aircraft, even in presence of ongoing concrete progressive failure (some penetration and spalling of the concrete wall

Plio-Pleistocene facies environments from the KBS Member, Koobi Fora Formation: implications for climate controls on the development of lake-margin hominin habitats in the northeast Turkana Basin (northwest Kenya).

PubMed

Lepre, Christopher J; Quinn, Rhonda L; Joordens, Josephine C A; Swisher, Carl C; Feibel, Craig S

2007-11-01

Climate change is hypothesized as a cause of major events of Plio-Pleistocene East African hominin evolution, but the vertically discontinuous and laterally confined nature of the relevant geological records has led to difficulties with assessing probable links between the two. High-resolution sedimentary sequences from lacustrine settings can provide comprehensive data of environmental changes and detailed correlations with well-established orbital and marine records of climate. Hominin-bearing deposits from Koobi Fora Ridge localities in the northeast Turkana Basin of Kenya are an archive of Plio-Pleistocene lake-margin sedimentation though significant developmental junctures of northern African climates, East African environments, and hominin evolution. This study examines alluvial channel and floodplain, nearshore lacustrine, and offshore lacustrine facies environments for the approximately 136-m-thick KBS Member (Koobi Fora Formation) exposed at the Koobi Fora Ridge. Aspects of the facies environments record information on the changing hydrosedimentary dynamics of the lake margin and give insights into potential climatic controls. Seasonal/yearly climate changes are represented by the varve-like laminations in offshore mudstones and the slickensides, dish-shaped fractures, and other paleosol features overprinted on floodplain strata. Vertical shifts between facies environments, however, are interpreted to indicate lake-level fluctuations deriving from longer-term, dry-wet periods in monsoonal rainfall. Recurrence periods for the inferred lake-level changes range from about 10,000 to 50,000 years, and several are consistent with the average estimated timescales of orbital precession ( approximately 20,000 years) and obliquity ( approximately 40,000 years). KBS Member facies environments from the Koobi Fora Ridge document the development of lake-margin hominin habitats in the northeast Turkana Basin. Environmental changes in these habitats may be a result of

GABA action in immature neocortical neurons directly depends on the availability of ketone bodies.

PubMed

Rheims, Sylvain; Holmgren, Carl D; Chazal, Genevieve; Mulder, Jan; Harkany, Tibor; Zilberter, Tanya; Zilberter, Yuri

2009-08-01

In the early postnatal period, energy metabolism in the suckling rodent brain relies to a large extent on metabolic pathways alternate to glucose such as the utilization of ketone bodies (KBs). However, how KBs affect neuronal excitability is not known. Using recordings of single NMDA and GABA-activated channels in neocortical pyramidal cells we studied the effects of KBs on the resting membrane potential (E(m)) and reversal potential of GABA-induced anionic currents (E(GABA)), respectively. We show that during postnatal development (P3-P19) if neocortical brain slices are adequately supplied with KBs, E(m) and E(GABA) are both maintained at negative levels of about -83 and -80 mV, respectively. Conversely, a KB deficiency causes a significant depolarization of both E(m) (>5 mV) and E(GABA) (>15 mV). The KB-mediated shift in E(GABA) is largely determined by the interaction of the NKCC1 cotransporter and Cl(-)/HCO3 transporter(s). Therefore, by inducing a hyperpolarizing shift in E(m) and modulating GABA signaling mode, KBs can efficiently control the excitability of neonatal cortical neurons.

Implementing the EuroFIR Document and Data Repositories as accessible resources of food composition information.

PubMed

Unwin, Ian; Jansen-van der Vliet, Martine; Westenbrink, Susanne; Presser, Karl; Infanger, Esther; Porubska, Janka; Roe, Mark; Finglas, Paul

2016-02-15

The EuroFIR Document and Data Repositories are being developed as accessible collections of source documents, including grey literature, and the food composition data reported in them. These Repositories will contain source information available to food composition database compilers when selecting their nutritional data. The Document Repository was implemented as searchable bibliographic records in the Europe PubMed Central database, which links to the documents online. The Data Repository will contain original data from source documents in the Document Repository. Testing confirmed the FoodCASE food database management system as a suitable tool for the input, documentation and quality assessment of Data Repository information. Data management requirements for the input and documentation of reported analytical results were established, including record identification and method documentation specifications. Document access and data preparation using the Repositories will provide information resources for compilers, eliminating duplicated work and supporting unambiguous referencing of data contributing to their compiled data. Copyright © 2014 Elsevier Ltd. All rights reserved.

SBR-Blood: systems biology repository for hematopoietic cells.

PubMed

Lichtenberg, Jens; Heuston, Elisabeth F; Mishra, Tejaswini; Keller, Cheryl A; Hardison, Ross C; Bodine, David M

2016-01-04

Extensive research into hematopoiesis (the development of blood cells) over several decades has generated large sets of expression and epigenetic profiles in multiple human and mouse blood cell types. However, there is no single location to analyze how gene regulatory processes lead to different mature blood cells. We have developed a new database framework called hematopoietic Systems Biology Repository (SBR-Blood), available online at http://sbrblood.nhgri.nih.gov, which allows user-initiated analyses for cell type correlations or gene-specific behavior during differentiation using publicly available datasets for array- and sequencing-based platforms from mouse hematopoietic cells. SBR-Blood organizes information by both cell identity and by hematopoietic lineage. The validity and usability of SBR-Blood has been established through the reproduction of workflows relevant to expression data, DNA methylation, histone modifications and transcription factor occupancy profiles. Published by Oxford University Press on behalf of Nucleic Acids Research 2015. This work is written by (a) US Government employee(s) and is in the public domain in the US.

Science is the first step to siting nuclear waste repositories

USGS Publications Warehouse

Neuzil, Christopher E.

2014-01-01

As Shaw [2014] notes, U.S. research on shale as a repository host was halted before expending anything close to the effort devoted to studying crystalline rock, salt, and - most notably - tuff at Yucca Mountain. The new political reality regarding Yucca Mountain may allow reconsideration of the decision to abandon research on shale as a repository host.

PGP repository: a plant phenomics and genomics data publication infrastructure.

PubMed

Arend, Daniel; Junker, Astrid; Scholz, Uwe; Schüler, Danuta; Wylie, Juliane; Lange, Matthias

2016-01-01

Plant genomics and phenomics represents the most promising tools for accelerating yield gains and overcoming emerging crop productivity bottlenecks. However, accessing this wealth of plant diversity requires the characterization of this material using state-of-the-art genomic, phenomic and molecular technologies and the release of subsequent research data via a long-term stable, open-access portal. Although several international consortia and public resource centres offer services for plant research data management, valuable digital assets remains unpublished and thus inaccessible to the scientific community. Recently, the Leibniz Institute of Plant Genetics and Crop Plant Research and the German Plant Phenotyping Network have jointly initiated the Plant Genomics and Phenomics Research Data Repository (PGP) as infrastructure to comprehensively publish plant research data. This covers in particular cross-domain datasets that are not being published in central repositories because of its volume or unsupported data scope, like image collections from plant phenotyping and microscopy, unfinished genomes, genotyping data, visualizations of morphological plant models, data from mass spectrometry as well as software and documents.The repository is hosted at Leibniz Institute of Plant Genetics and Crop Plant Research using e!DAL as software infrastructure and a Hierarchical Storage Management System as data archival backend. A novel developed data submission tool was made available for the consortium that features a high level of automation to lower the barriers of data publication. After an internal review process, data are published as citable digital object identifiers and a core set of technical metadata is registered at DataCite. The used e!DAL-embedded Web frontend generates for each dataset a landing page and supports an interactive exploration. PGP is registered as research data repository at BioSharing.org, re3data.org and OpenAIRE as valid EU Horizon 2020 open

PGP repository: a plant phenomics and genomics data publication infrastructure

PubMed Central

Arend, Daniel; Junker, Astrid; Scholz, Uwe; Schüler, Danuta; Wylie, Juliane; Lange, Matthias

2016-01-01

Plant genomics and phenomics represents the most promising tools for accelerating yield gains and overcoming emerging crop productivity bottlenecks. However, accessing this wealth of plant diversity requires the characterization of this material using state-of-the-art genomic, phenomic and molecular technologies and the release of subsequent research data via a long-term stable, open-access portal. Although several international consortia and public resource centres offer services for plant research data management, valuable digital assets remains unpublished and thus inaccessible to the scientific community. Recently, the Leibniz Institute of Plant Genetics and Crop Plant Research and the German Plant Phenotyping Network have jointly initiated the Plant Genomics and Phenomics Research Data Repository (PGP) as infrastructure to comprehensively publish plant research data. This covers in particular cross-domain datasets that are not being published in central repositories because of its volume or unsupported data scope, like image collections from plant phenotyping and microscopy, unfinished genomes, genotyping data, visualizations of morphological plant models, data from mass spectrometry as well as software and documents. The repository is hosted at Leibniz Institute of Plant Genetics and Crop Plant Research using e!DAL as software infrastructure and a Hierarchical Storage Management System as data archival backend. A novel developed data submission tool was made available for the consortium that features a high level of automation to lower the barriers of data publication. After an internal review process, data are published as citable digital object identifiers and a core set of technical metadata is registered at DataCite. The used e!DAL-embedded Web frontend generates for each dataset a landing page and supports an interactive exploration. PGP is registered as research data repository at BioSharing.org, re3data.org and OpenAIRE as valid EU Horizon 2020 open

Factors Affecting Faculty Acceptance and Use of Institutional Repositories in Thailand

ERIC Educational Resources Information Center

Ammarukleart, Sujira

2017-01-01

Institutional repositories have been introduced as an innovative and alternative technology for scholarly communication and have received considerable attention from scholars across disciplines and around the globe. While some universities in Thailand have developed and implemented institutional repositories for nearly a decade, knowledge of the…

Geoscience Digital Data Resource and Repository Service

NASA Astrophysics Data System (ADS)

Mayernik, M. S.; Schuster, D.; Hou, C. Y.

2017-12-01

The open availability and wide accessibility of digital data sets is becoming the norm for geoscience research. The National Science Foundation (NSF) instituted a data management planning requirement in 2011, and many scientific publishers, including the American Geophysical Union and the American Meteorological Society, have recently implemented data archiving and citation policies. Many disciplinary data facilities exist around the community to provide a high level of technical support and expertise for archiving data of particular kinds, or for particular projects. However, a significant number of geoscience research projects do not have the same level of data facility support due to a combination of several factors, including the research project's size, funding limitations, or topic scope that does not have a clear facility match. These projects typically manage data on an ad hoc basis without limited long-term management and preservation procedures. The NSF is supporting a workshop to be held in Summer of 2018 to develop requirements and expectations for a Geoscience Digital Data Resource and Repository Service (GeoDaRRS). The vision for the prospective GeoDaRRS is to complement existing NSF-funded data facilities by providing: 1) data management planning support resources for the general community, and 2) repository services for researchers who have data that do not fit in any existing repository. Functionally, the GeoDaRRS would support NSF-funded researchers in meeting data archiving requirements set by the NSF and publishers for geosciences, thereby ensuring the availability of digital data for use and reuse in scientific research going forward. This presentation will engage the AGU community in discussion about the needs for a new digital data repository service, specifically to inform the forthcoming GeoDaRRS workshop.

Digitizing dissertations for an institutional repository: a process and cost analysis.

PubMed

Piorun, Mary; Palmer, Lisa A

2008-07-01

This paper describes the Lamar Soutter Library's process and costs associated with digitizing 300 doctoral dissertations for a newly implemented institutional repository at the University of Massachusetts Medical School. Project tasks included identifying metadata elements, obtaining and tracking permissions, converting the dissertations to an electronic format, and coordinating workflow between library departments. Each dissertation was scanned, reviewed for quality control, enhanced with a table of contents, processed through an optical character recognition function, and added to the institutional repository. Three hundred and twenty dissertations were digitized and added to the repository for a cost of $23,562, or $0.28 per page. Seventy-four percent of the authors who were contacted (n = 282) granted permission to digitize their dissertations. Processing time per title was 170 minutes, for a total processing time of 906 hours. In the first 17 months, full-text dissertations in the collection were downloaded 17,555 times. Locally digitizing dissertations or other scholarly works for inclusion in institutional repositories can be cost effective, especially if small, defined projects are chosen. A successful project serves as an excellent recruitment strategy for the institutional repository and helps libraries build new relationships. Challenges include workflow, cost, policy development, and copyright permissions.

Digitizing Dissertations for an Institutional Repository: A Process and Cost Analysis*

PubMed Central

Piorun, Mary; Palmer, Lisa A.

2008-01-01

Objective: This paper describes the Lamar Soutter Library's process and costs associated with digitizing 300 doctoral dissertations for a newly implemented institutional repository at the University of Massachusetts Medical School. Methodology: Project tasks included identifying metadata elements, obtaining and tracking permissions, converting the dissertations to an electronic format, and coordinating workflow between library departments. Each dissertation was scanned, reviewed for quality control, enhanced with a table of contents, processed through an optical character recognition function, and added to the institutional repository. Results: Three hundred and twenty dissertations were digitized and added to the repository for a cost of $23,562, or $0.28 per page. Seventy-four percent of the authors who were contacted (n = 282) granted permission to digitize their dissertations. Processing time per title was 170 minutes, for a total processing time of 906 hours. In the first 17 months, full-text dissertations in the collection were downloaded 17,555 times. Conclusion: Locally digitizing dissertations or other scholarly works for inclusion in institutional repositories can be cost effective, especially if small, defined projects are chosen. A successful project serves as an excellent recruitment strategy for the institutional repository and helps libraries build new relationships. Challenges include workflow, cost, policy development, and copyright permissions. PMID:18654648

A repository based on a dynamically extensible data model supporting multidisciplinary research in neuroscience.

PubMed

Corradi, Luca; Porro, Ivan; Schenone, Andrea; Momeni, Parastoo; Ferrari, Raffaele; Nobili, Flavio; Ferrara, Michela; Arnulfo, Gabriele; Fato, Marco M

2012-10-08

Robust, extensible and distributed databases integrating clinical, imaging and molecular data represent a substantial challenge for modern neuroscience. It is even more difficult to provide extensible software environments able to effectively target the rapidly changing data requirements and structures of research experiments. There is an increasing request from the neuroscience community for software tools addressing technical challenges about: (i) supporting researchers in the medical field to carry out data analysis using integrated bioinformatics services and tools; (ii) handling multimodal/multiscale data and metadata, enabling the injection of several different data types according to structured schemas; (iii) providing high extensibility, in order to address different requirements deriving from a large variety of applications simply through a user runtime configuration. A dynamically extensible data structure supporting collaborative multidisciplinary research projects in neuroscience has been defined and implemented. We have considered extensibility issues from two different points of view. First, the improvement of data flexibility has been taken into account. This has been done through the development of a methodology for the dynamic creation and use of data types and related metadata, based on the definition of "meta" data model. This way, users are not constrainted to a set of predefined data and the model can be easily extensible and applicable to different contexts. Second, users have been enabled to easily customize and extend the experimental procedures in order to track each step of acquisition or analysis. This has been achieved through a process-event data structure, a multipurpose taxonomic schema composed by two generic main objects: events and processes. Then, a repository has been built based on such data model and structure, and deployed on distributed resources thanks to a Grid-based approach. Finally, data integration aspects have been

A repository based on a dynamically extensible data model supporting multidisciplinary research in neuroscience

PubMed Central

2012-01-01

Background Robust, extensible and distributed databases integrating clinical, imaging and molecular data represent a substantial challenge for modern neuroscience. It is even more difficult to provide extensible software environments able to effectively target the rapidly changing data requirements and structures of research experiments. There is an increasing request from the neuroscience community for software tools addressing technical challenges about: (i) supporting researchers in the medical field to carry out data analysis using integrated bioinformatics services and tools; (ii) handling multimodal/multiscale data and metadata, enabling the injection of several different data types according to structured schemas; (iii) providing high extensibility, in order to address different requirements deriving from a large variety of applications simply through a user runtime configuration. Methods A dynamically extensible data structure supporting collaborative multidisciplinary research projects in neuroscience has been defined and implemented. We have considered extensibility issues from two different points of view. First, the improvement of data flexibility has been taken into account. This has been done through the development of a methodology for the dynamic creation and use of data types and related metadata, based on the definition of “meta” data model. This way, users are not constrainted to a set of predefined data and the model can be easily extensible and applicable to different contexts. Second, users have been enabled to easily customize and extend the experimental procedures in order to track each step of acquisition or analysis. This has been achieved through a process-event data structure, a multipurpose taxonomic schema composed by two generic main objects: events and processes. Then, a repository has been built based on such data model and structure, and deployed on distributed resources thanks to a Grid-based approach. Finally, data

Multiscale Model Simulations of Temperature and Relative Humidity for the License Application of the Proposed Yucca Mountain Repository

NASA Astrophysics Data System (ADS)

Buscheck, T.; Glascoe, L.; Sun, Y.; Gansemer, J.; Lee, K.

2003-12-01

For the proposed Yucca Mountain geologic repository for high-level nuclear waste, the planned method of disposal involves the emplacement of cylindrical packages containing the waste inside horizontal tunnels, called emplacement drifts, bored several hundred meters below the ground surface. The emplacement drifts reside in highly fractured, partially saturated volcanic tuff. An important phenomenological consideration for the licensing of the proposed repository at Yucca Mountain is the generation of decay heat by the emplaced waste and the consequences of this decay heat. Changes in temperature will affect the hydrologic and chemical environment at Yucca Mountain. A thermohydrologic-modeling tool is necessary to support the performance assessment of the Engineered Barrier System (EBS) of the proposed repository. This modeling tool must simultaneously account for processes occurring at a scale of a few tens of centimeters around individual waste packages, for processes occurring around the emplacement drifts themselves, and for processes occurring at the multi-kilometer scale of the mountain. Additionally, many other features must be considered including non-isothermal, multiphase-flow in fractured porous rock of variable liquid-phase saturation and thermal radiation and convection in open cavities. The Multiscale Thermohydrologic Model (MSTHM) calculates the following thermohydrologic (TH) variables: temperature, relative humidity, liquid-phase saturation, evaporation rate, air-mass fraction, gas-phase pressure, capillary pressure, and liquid- and gas-phase fluxes. The TH variables are determined as a function of position along each of the emplacement drifts in the repository and as a function of waste-package (WP) type. These variables are determined at various generic locations within the emplacement drifts, including the waste package and drip-shield surfaces and in the invert; they are also determined at various generic locations in the adjoining host rock

Knowledge-based system verification and validation

NASA Technical Reports Server (NTRS)

Johnson, Sally C.

1990-01-01

The objective of this task is to develop and evaluate a methodology for verification and validation (V&V) of knowledge-based systems (KBS) for space station applications with high reliability requirements. The approach consists of three interrelated tasks. The first task is to evaluate the effectiveness of various validation methods for space station applications. The second task is to recommend requirements for KBS V&V for Space Station Freedom (SSF). The third task is to recommend modifications to the SSF to support the development of KBS using effectiveness software engineering and validation techniques. To accomplish the first task, three complementary techniques will be evaluated: (1) Sensitivity Analysis (Worchester Polytechnic Institute); (2) Formal Verification of Safety Properties (SRI International); and (3) Consistency and Completeness Checking (Lockheed AI Center). During FY89 and FY90, each contractor will independently demonstrate the user of his technique on the fault detection, isolation, and reconfiguration (FDIR) KBS or the manned maneuvering unit (MMU), a rule-based system implemented in LISP. During FY91, the application of each of the techniques to other knowledge representations and KBS architectures will be addressed. After evaluation of the results of the first task and examination of Space Station Freedom V&V requirements for conventional software, a comprehensive KBS V&V methodology will be developed and documented. Development of highly reliable KBS's cannot be accomplished without effective software engineering methods. Using the results of current in-house research to develop and assess software engineering methods for KBS's as well as assessment of techniques being developed elsewhere, an effective software engineering methodology for space station KBS's will be developed, and modification of the SSF to support these tools and methods will be addressed.

An open data repository and a data processing software toolset of an equivalent Nordic grid model matched to historical electricity market data.

PubMed

Vanfretti, Luigi; Olsen, Svein H; Arava, V S Narasimham; Laera, Giuseppe; Bidadfar, Ali; Rabuzin, Tin; Jakobsen, Sigurd H; Lavenius, Jan; Baudette, Maxime; Gómez-López, Francisco J

2017-04-01

This article presents an open data repository, the methodology to generate it and the associated data processing software developed to consolidate an hourly snapshot historical data set for the year 2015 to an equivalent Nordic power grid model (aka Nordic 44), the consolidation was achieved by matching the model׳s physical response w.r.t historical power flow records in the bidding regions of the Nordic grid that are available from the Nordic electricity market agent, Nord Pool. The model is made available in the form of CIM v14, Modelica and PSS/E (Siemens PTI) files. The Nordic 44 model in Modelica and PSS/E were first presented in the paper titled "iTesla Power Systems Library (iPSL): A Modelica library for phasor time-domain simulations" (Vanfretti et al., 2016) [1] for a single snapshot. In the digital repository being made available with the submission of this paper (SmarTSLab_Nordic44 Repository at Github, 2016) [2], a total of 8760 snapshots (for the year 2015) that can be used to initialize and execute dynamic simulations using tools compatible with CIM v14, the Modelica language and the proprietary PSS/E tool are provided. The Python scripts to generate the snapshots (processed data) are also available with all the data in the GitHub repository (SmarTSLab_Nordic44 Repository at Github, 2016) [2]. This Nordic 44 equivalent model was also used in iTesla project (iTesla) [3] to carry out simulations within a dynamic security assessment toolset (iTesla, 2016) [4], and has been further enhanced during the ITEA3 OpenCPS project (iTEA3) [5]. The raw, processed data and output models utilized within the iTesla platform (iTesla, 2016) [4] are also available in the repository. The CIM and Modelica snapshots of the "Nordic 44" model for the year 2015 are available in a Zenodo repository.

Siting Patterns of Nuclear Waste Repositories.

ERIC Educational Resources Information Center

Solomon, Barry D.; Shelley, Fred M.

1988-01-01

Provides an inventory of international radioactive waste-management policies and repository siting decisions for North America, Central and South America, Europe, Asia, and Africa. This discussion stresses the important role of demographic, geologic, and political factors in siting decisions. (Author/BSR)

Childhood Vesicoureteral Reflux Studies: Registries and Repositories Sources and Nosology

PubMed Central

Chesney, Russell W.; Patters, Andrea B.

2012-01-01

Despite several recent studies, the advisability of antimicrobial prophylaxis and certain imaging studies for urinary tract infections (UTIs) remains controversial. The role of vesicoureteral reflux (VUR) on the severity and re-infection rates for UTIs is also difficult to assess. Registries and repositories of data and biomaterials from clinical studies in children with VUR are valuable. Disease registries are collections of secondary data related to patients with a specific diagnosis, condition or procedure. Registries differ from indices in that they contain more extensive data. A research repository is an entity that receives, stores, processes and/or disseminates specimens (or other materials) as needed. It encompasses the physical location as well as the full range of activities associated with its operation. It may also be referred to as a biorepository. This report provides information about some current registries and repositories that include data and samples from children with VUR. It also describes the heterogeneous nature of the subjects, as some registries and repositories include only data or samples from patients with primary reflux while others also include those from patients with syndromic or secondary reflux. PMID:23044377

Childhood vesicoureteral reflux studies: registries and repositories sources and nosology.

PubMed

Chesney, Russell W; Patters, Andrea B

2013-12-01

Despite several recent studies, the advisability of antimicrobial prophylaxis and certain imaging studies for urinary tract infections (UTIs) remains controversial. The role of vesicoureteral reflux (VUR) on the severity and re-infection rates for UTIs is also difficult to assess. Registries and repositories of data and biomaterials from clinical studies in children with VUR are valuable. Disease registries are collections of secondary data related to patients with a specific diagnosis, condition or procedure. Registries differ from indices in that they contain more extensive data. A research repository is an entity that receives, stores, processes and/or disseminates specimens (or other materials) as needed. It encompasses the physical location as well as the full range of activities associated with its operation. It may also be referred to as a biorepository. This report provides information about some current registries and repositories that include data and samples from children with VUR. It also describes the heterogeneous nature of the subjects, as some registries and repositories include only data or samples from patients with primary reflux while others also include those from patients with syndromic or secondary reflux. Copyright © 2012 Journal of Pediatric Urology Company. All rights reserved.

User Oriented Platform for Data Analytics in Medical Imaging Repositories.

PubMed

Valerio, Miguel; Godinho, Tiago Marques; Costa, Carlos

2016-01-01

The production of medical imaging studies and associated data has been growing in the last decades. Their primary use is to support medical diagnosis and treatment processes. However, the secondary use of the tremendous amount of stored data is generally more limited. Nowadays, medical imaging repositories have turned into rich databanks holding not only the images themselves, but also a wide range of metadata related to the medical practice. Exploring these repositories through data analysis and business intelligence techniques has the potential of increasing the efficiency and quality of the medical practice. Nevertheless, the continuous production of tremendous amounts of data makes their analysis difficult by conventional approaches. This article proposes a novel automated methodology to derive knowledge from medical imaging repositories that does not disrupt the regular medical practice. Our method is able to apply statistical analysis and business intelligence techniques directly on top of live institutional repositories. It is a Web-based solution that provides extensive dashboard capabilities, including complete charting and reporting options, combined with data mining components. Moreover, it enables the operator to set a wide multitude of query parameters and operators through the use of an intuitive graphical interface.

NUTRITION w/Repository into MELFI

NASA Image and Video Library

2009-07-30

ISS020-E-026348 (30 July 2009) --- Astronaut Tim Kopra, Expedition 20 flight engineer, smiles for the camera as he completes the task of placing samples taken for the Nutritional Status Assessment (NUTRITION) w/Repository study into the Minus Eighty Degree Laboratory Freezer for ISS (MELFI) in the Kibo laboratory of the International Space Station.

The Function Biomedical Informatics Research Network Data Repository.

PubMed

Keator, David B; van Erp, Theo G M; Turner, Jessica A; Glover, Gary H; Mueller, Bryon A; Liu, Thomas T; Voyvodic, James T; Rasmussen, Jerod; Calhoun, Vince D; Lee, Hyo Jong; Toga, Arthur W; McEwen, Sarah; Ford, Judith M; Mathalon, Daniel H; Diaz, Michele; O'Leary, Daniel S; Jeremy Bockholt, H; Gadde, Syam; Preda, Adrian; Wible, Cynthia G; Stern, Hal S; Belger, Aysenil; McCarthy, Gregory; Ozyurt, Burak; Potkin, Steven G

2016-01-01

The Function Biomedical Informatics Research Network (FBIRN) developed methods and tools for conducting multi-scanner functional magnetic resonance imaging (fMRI) studies. Method and tool development were based on two major goals: 1) to assess the major sources of variation in fMRI studies conducted across scanners, including instrumentation, acquisition protocols, challenge tasks, and analysis methods, and 2) to provide a distributed network infrastructure and an associated federated database to host and query large, multi-site, fMRI and clinical data sets. In the process of achieving these goals the FBIRN test bed generated several multi-scanner brain imaging data sets to be shared with the wider scientific community via the BIRN Data Repository (BDR). The FBIRN Phase 1 data set consists of a traveling subject study of 5 healthy subjects, each scanned on 10 different 1.5 to 4 T scanners. The FBIRN Phase 2 and Phase 3 data sets consist of subjects with schizophrenia or schizoaffective disorder along with healthy comparison subjects scanned at multiple sites. In this paper, we provide concise descriptions of FBIRN's multi-scanner brain imaging data sets and details about the BIRN Data Repository instance of the Human Imaging Database (HID) used to publicly share the data. Copyright © 2015 Elsevier Inc. All rights reserved.

The Function Biomedical Informatics Research Network Data Repository

PubMed Central

Keator, David B.; van Erp, Theo G.M.; Turner, Jessica A.; Glover, Gary H.; Mueller, Bryon A.; Liu, Thomas T.; Voyvodic, James T.; Rasmussen, Jerod; Calhoun, Vince D.; Lee, Hyo Jong; Toga, Arthur W.; McEwen, Sarah; Ford, Judith M.; Mathalon, Daniel H.; Diaz, Michele; O’Leary, Daniel S.; Bockholt, H. Jeremy; Gadde, Syam; Preda, Adrian; Wible, Cynthia G.; Stern, Hal S.; Belger, Aysenil; McCarthy, Gregory; Ozyurt, Burak; Potkin, Steven G.

2015-01-01

The Function Biomedical Informatics Research Network (FBIRN) developed methods and tools for conducting multi-scanner functional magnetic resonance imaging (fMRI) studies. Method and tool development were based on two major goals: 1) to assess the major sources of variation in fMRI studies conducted across scanners, including instrumentation, acquisition protocols, challenge tasks, and analysis methods, and 2) to provide a distributed network infrastructure and an associated federated database to host and query large, multi-site, fMRI and clinical datasets. In the process of achieving these goals the FBIRN test bed generated several multi-scanner brain imaging data sets to be shared with the wider scientific community via the BIRN Data Repository (BDR). The FBIRN Phase 1 dataset consists of a traveling subject study of 5 healthy subjects, each scanned on 10 different 1.5 to 4 Tesla scanners. The FBIRN Phase 2 and Phase 3 datasets consist of subjects with schizophrenia or schizoaffective disorder along with healthy comparison subjects scanned at multiple sites. In this paper, we provide concise descriptions of FBIRN’s multi-scanner brain imaging data sets and details about the BIRN Data Repository instance of the Human Imaging Database (HID) used to publicly share the data. PMID:26364863

10 CFR 60.112 - Overall system performance objective for the geologic repository after permanent closure.

Code of Federal Regulations, 2010 CFR

2010-01-01

... repository after permanent closure. 60.112 Section 60.112 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Technical Criteria Performance Objectives § 60.112 Overall system performance objective for the geologic repository after permanent closure...

The siting program of geological repository for spent fuel/high-level waste in Czech Republic

DOE Office of Scientific and Technical Information (OSTI.GOV)

Novotny, P.

1993-12-31

The management of high-level waste in Czech Republic have a very short history, because before the year 1989 spent nuclear fuel was re-exported back to USSR. The project ``Geological research of HLW repository in Czech Republic`` was initiated during 1990 by the Ministry of the Environment of the Czech Republic and by this project delegated the Czech Geological Survey (CGU) Prague. The first CGU project late in 1990 for multibarrier concept has proposed a geological repository to be located at a depth of about 500 m. Screening and studies of potential sites for repository started in 1991. First stage representedmore » regional siting of the Czech Republic for perspective rock types and massifs. In cooperation with GEOPHYSICS Co., Geophysical Institute of the Czech Academy of Sciences and Charles University Prague 27 perspective regions were selected, using criteria IAEA. This work in the Czech Republic was possible thanks to the detailed geological studies done in the past and thanks to the numerous archive data, concentrated in the central geological archive GEOFOND. Selection of perspective sites also respected natural conservation regions, regions conserving water and mineral waters resources. CGU opened up contact with countries with similar geological situation and started cooperation with SKB (Swedish Nuclear Fuel and Waste Management Co.). The Project of geological research for the next 10 years is a result of these activities.« less

The FLEXGene repository: exploiting the fruits of the genome projects by creating a needed resource to face the challenges of the post-genomic era.

PubMed

Brizuela, Leonardo; Richardson, Aaron; Marsischky, Gerald; Labaer, Joshua

2002-01-01

Thanks to the results of the multiple completed and ongoing genome sequencing projects and to the newly available recombination-based cloning techniques, it is now possible to build gene repositories with no precedent in their composition, formatting, and potential. This new type of gene repository is necessary to address the challenges imposed by the post-genomic era, i.e., experimentation on a genome-wide scale. We are building the FLEXGene (Full Length EXpression-ready) repository. This unique resource will contain clones representing the complete ORFeome of different organisms, including Homo sapiens as well as several pathogens and model organisms. It will consist of a comprehensive, characterized (sequence-verified), and arrayed gene repository. This resource will allow full exploitation of the genomic information by enabling genome-wide scale experimentation at the level of functional/phenotypic assays as well as at the level of protein expression, purification, and analysis. Here we describe the rationale and construction of this resource and focus on the data obtained from the Saccharomyces cerevisiae project.

Knowledge-based system for flight information management. Thesis

NASA Technical Reports Server (NTRS)

Ricks, Wendell R.

1990-01-01

The use of knowledge-based system (KBS) architectures to manage information on the primary flight display (PFD) of commercial aircraft is described. The PFD information management strategy used tailored the information on the PFD to the tasks the pilot performed. The KBS design and implementation of the task-tailored PFD information management application is described. The knowledge acquisition and subsequent system design of a flight-phase-detection KBS is also described. The flight-phase output of this KBS was used as input to the task-tailored PFD information management KBS. The implementation and integration of this KBS with existing aircraft systems and the other KBS is described. The flight tests are examined of both KBS's, collectively called the Task-Tailored Flight Information Manager (TTFIM), which verified their implementation and integration, and validated the software engineering advantages of the KBS approach in an operational environment.

Assessment of the long-term durability of concrete in radioactive waste repositories

DOE Office of Scientific and Technical Information (OSTI.GOV)

Atkinson, A.; Goult, D.J.; Hearne, J.A.

1986-01-01

A preliminary assessment of the long-term durability of concrete in a repository sited in clay is presented. The assessment is based on recorded experience of concrete structures and both field and laboratory studies. It is also supported by results of the examination of a concrete sample which had been buried in clay for 43 years. The engineering lifetime of a 1 m thick reinforced concrete slab, with one face in contact with clay, and the way in which pH in the repository as a whole is likely to vary with time have both been estimated from available data. The estimatesmore » indicate that engineering lifetimes of about 10/sup 3/ years are expected (providing that sulfate resisting cement is used) and that pH is likely to remain above 10.5 for about 10/sup 6/ years.« less

Transuranic inventory reduction in repository by partitioning and transmutation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kang, C.H.; Kazimi, M.S.

1992-01-01

The promise of a new reprocessing technology and the issuance of Environmental Protection Agency (EPA) and U.S. Nuclear Regulatory Commission regulations concerning a geologic repository rekindle the interest in partitioning and transmutation of transuranic (TRU) elements from discharged reactor fuel as a high level waste management option. This paper investigates the TRU repository inventory reduction capability of the proposed advanced liquid metal reactors (ALMRs) and integral fast reactors (IFRs) as well as the plutonium recycled light water reactors (LWRs).

Pentacyclic ingamine-type alkaloids, a new antiplasmodial pharmacophore from the marine sponge petrosid Ng5 Sp5

USDA-ARS?s Scientific Manuscript database

Two new pentacyclic ingamine- type alkaloids, namely 22(S)-hydroxyingamine A (2) and dihydroingenamine D (3), together with the known ingamine A (1) have been isolated from marine sponge Petrosid Ng5 Sp5 (Family: Petrosiidae) obtained from the open repository of National Cancer Institute, USA. The s...

Prototype repository: A full scale experiment at Äspö HRL

NASA Astrophysics Data System (ADS)

Johannesson, Lars-Erik; Börgesson, Lennart; Goudarzi, Reza; Sandén, Torbjörn; Gunnarsson, David; Svemar, Christer

At Äspö Hard Rock Laboratory a full scale test of the Swedish concept for disposal of nuclear waste (KBS-3V) is in progress. The Prototype Repository project consists of two sections. The installation of the first section was made during summer and autumn 2001 and the second section during spring and summer 2003. Section 1 consists of four full-scale deposition holes, copper canisters equipped with electrical heaters, bentonite buffer consisting of blocks and pellets and a deposition tunnel backfilled with a mixture of bentonite and crushed rock, ending with a concrete plug. Section 2 consists of two full-scale deposition holes with a backfilled tunnel section and ends also with a concrete plug. Altogether 84 large bentonite blocks, with a total weight of about 130 tons, were installed and more than 2000 tons of backfill material were mixed and compacted in situ. Earlier developed techniques for both manufacturing and installing the buffer and the backfill were used in the project. Measurements and data from the installation allow calculations of the expected density in the buffer and in different parts of the backfill. The bentonite buffer in deposition holes 1, 3, 5 and 6, the backfill and the surrounding rock are instrumented with gauges for measuring temperature, water pressure, total pressure, relative humidity, resistivity, canister displacement and rock stresses. The instruments are connected to data acquisition systems by cables protected by tubes. These tubes are led through the rock in watertight lead-throughs to a nearby tunnel where the data acquisition systems are situated. More than 1100 transducers have been installed in the rock, buffer and the backfill. The technique for protecting the transducers from high water and swelling pressure was developed in this and preceding projects and furthermore different designs of transducers are used for the same type of measurement in order to compare their behaviour. The deposition holes have different water

Looking for Skeletons in the Data Centre `Cupboard': How Repository Certification Can Help

NASA Astrophysics Data System (ADS)

Sorvari, S.; Glaves, H.

2017-12-01

There has been a national geoscience repository at the British Geological Survey (or one of its previous incarnations) almost since its inception in 1835. This longevity has resulted in vast amounts of analogue material and, more recently, digital data some of which has been collected by our scientists but much more has been acquired either through various legislative obligations or donated from various sources. However, the role and operation of the UK National Geoscience Data Centre (NGDC) in the 21st Century is very different to that of the past, with new systems and procedures dealing with predominantly digital data. A web-based ingestion portal allows users to submit their data directly to the NGDC while online services provide discovery and access to data and derived products. Increasingly we are also required to implement an array of standards e.g. ISO, OGC, W3C, best practices e.g. FAIR and legislation e.g. EU INSPIRE Directive; whilst at the same time needing to justifying our very existence to our funding agency and hosting organisation. External pressures to demonstrate that we can be recognised as a trusted repository by researchers, various funding agencies, publishers and other related entities have forced us to look at how we function, and to benchmark our operations against those of other organisations and current relevant standards such as those laid down by different repository certification processes. Following an assessment of the various options, the WDS/DSA certification process was selected as the most appropriate route for accreditation of NGDC as a trustworthy repository. It provided a suitable framework for reviewing the current systems, procedures and best practices. Undertaking this process allowed us to identify where the NGDC already has robust systems in place and where there were gaps and deficiencies in current practices. The WDS/DSA assessment process also helped to reinforce best practice throughout the NGDC and demonstrated that

Functional requirements for a central research imaging data repository.

PubMed

Franke, Thomas; Gruetz, Romanus; Dickmann, Frank

2013-01-01

The current situation at many university medical centers regarding the management of biomedical research imaging data leaves much to be desired. In contrast to the recommendations of the German Research Foundation (DFG) and the German Council of Sciences and Humanities regarding the professional management of research data, there are commonly many individual data pools for research data in each institute and the management remains the responsibility of the researcher. A possible solution for this situation would be to install local central repositories for biomedical research imaging data. In this paper, we developed a scenario based on abstracted use-cases for institutional research undertakings as well as collaborative biomedical research projects and analyzed the functional requirements that a local repository would have to fulfill. We determined eight generic categories of functional requirements, which can be viewed as a basic guideline for the minimum functionality of a central repository for biomedical research imaging data.

Scientific information repository assisting reflectance spectrometry in legal medicine.

PubMed

Belenki, Liudmila; Sterzik, Vera; Bohnert, Michael; Zimmermann, Klaus; Liehr, Andreas W

2012-06-01

Reflectance spectrometry is a fast and reliable method for the characterization of human skin if the spectra are analyzed with respect to a physical model describing the optical properties of human skin. For a field study performed at the Institute of Legal Medicine and the Freiburg Materials Research Center of the University of Freiburg, a scientific information repository has been developed, which is a variant of an electronic laboratory notebook and assists in the acquisition, management, and high-throughput analysis of reflectance spectra in heterogeneous research environments. At the core of the repository is a database management system hosting the master data. It is filled with primary data via a graphical user interface (GUI) programmed in Java, which also enables the user to browse the database and access the results of data analysis. The latter is carried out via Matlab, Python, and C programs, which retrieve the primary data from the scientific information repository, perform the analysis, and store the results in the database for further usage.

Task-Based Navigation of a Taxonomy Interface to a Digital Repository

ERIC Educational Resources Information Center

Khoo, Christopher S. G.; Wang, Zhonghong; Chaudhry, Abdus Sattar

2012-01-01

Introduction: This is a study of hierarchical navigation; how users browse a taxonomy-based interface to an organizational repository to locate information resources. The study is part of a project to develop a taxonomy for an library and information science department to organize resources and support user browsing in a digital repository.…

A Comparison of Subject and Institutional Repositories in Self-Archiving Practices

ERIC Educational Resources Information Center

Xia, Jingfeng

2008-01-01

The disciplinary culture theory presumes that if a scholar has been familiar with self-archiving through an existing subject-based repository, this scholar will be more enthusiastic about contributing his/her research to an institutional repository than one who has not had the experience. To test the theory, this article examines self-archiving…

10 CFR 63.111 - Performance objectives for the geologic repository operations area through permanent closure.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Performance objectives for the geologic repository... (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC REPOSITORY AT YUCCA MOUNTAIN, NEVADA... repository operations area through permanent closure. (a) Protection against radiation exposures and releases...

10 CFR 63.161 - Emergency plan for the geologic repository operations area through permanent closure.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Emergency plan for the geologic repository operations area... OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC REPOSITORY AT YUCCA MOUNTAIN, NEVADA Emergency Planning Criteria § 63.161 Emergency plan for the geologic repository operations area through permanent...

The Situation of Open Access Institutional Repositories in Spain: 2009 Report

ERIC Educational Resources Information Center

Melero, Remedios; Abadal, Ernest; Abad, Francisca; Rodriguez-Gairin, Josep Manel

2009-01-01

Introduction: The DRIVER I project drew up a detailed report of European repositories based on data gathered in a survey in which Spain's participation was very low. This created a highly distorted image of the implementation of repositories in Spain. This study aims to analyse the current state of Spanish open-access institutional repositories…

Virtual Knowledge Brokering: Describing the Roles and Strategies Used by Knowledge Brokers in a Pediatric Physiotherapy Virtual Community of Practice.

PubMed

Hurtubise, Karen; Rivard, Lisa; Héguy, Léa; Berbari, Jade; Camden, Chantal

2016-01-01

Knowledge transfer in pediatric rehabilitation is challenging and requires active, multifaceted strategies. The use of knowledge brokers (KBs) is one such strategy noted to promote clinician behavior change. The success of using KBs to transfer knowledge relies on their ability to adapt to ever-changing clinical contexts. In addition, with the rapid growth of online platforms as knowledge transfer forums, KBs must become effective in virtual environments. Although the role of KBs has been studied in various clinical contexts, their emerging role in specific online environments designed to support evidence-based behavior change has not yet been described. Our objective is to describe the roles of, and strategies used by, four KBs involved in a virtual community of practice to guide and inform future online KB interventions. A descriptive design guided this study and a thematic content analysis process was used to analyze online KB postings. The Promoting Action on Research in Health Sciences knowledge transfer framework and online andragogical learning theories assisted in the coding. A thematic map was created illustrating the links between KBs' strategies and emerging roles in the virtual environment. We analyzed 95 posts and identified three roles: 1) context architect: promoting a respectful learning environment, 2) knowledge sharing promoter: building capacity, and 3) linkage creator: connecting research-to-practice. Strategies used by KBs reflected invitational, constructivism, and connectivism approaches, with roles and strategies changing over time. This study increases our understanding of the actions of KBs in virtual contexts to foster uptake of research evidence in pediatric physiotherapy. Our results provide valuable information about the knowledge and skills required by individuals to fulfill this role in virtual environments.

An ontology based information system for the management of institutional repository's collections

NASA Astrophysics Data System (ADS)

Tsolakidis, A.; Kakoulidis, P.; Skourlas, C.

2015-02-01

In this paper we discuss a simple methodological approach to create, and customize institutional repositories for the domain of the technological education. The use of the open source software platform of DSpace is proposed to build up the repository application and provide access to digital resources including research papers, dissertations, administrative documents, educational material, etc. Also the use of owl ontologies is proposed for indexing and accessing the various, heterogeneous items stored in the repository. Customization and operation of a platform for the selection and use of terms or parts of similar existing owl ontologies is also described. This platform could be based on the open source software Protégé that supports owl, is widely used, and also supports visualization, SPARQL etc. The combined use of the owl platform and the DSpace repository form a basis for creating customized ontologies, accommodating the semantic metadata of items and facilitating searching.

Characteristics of potential repository wastes. Volume 2

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1992-07-01

The LWR spent fuels discussed in Volume 1 of this report comprise about 99% of all domestic non-reprocessed spent fuel. In this report we discuss other types of spent fuels which, although small in relative quantity, consist of a number of diverse types, sizes, and compositions. Many of these fuels are candidates for repository disposal. Some non-LWR spent fuels are currently reprocessed or are scheduled for reprocessing in DOE facilities at the Savannah River Site, Hanford Site, and the Idaho National Engineering Laboratory. It appears likely that the reprocessing of fuels that have been reprocessed in the past will continuemore » and that the resulting high-level wastes will become part of defense HLW. However, it is not entirely clear in some cases whether a given fuel will be reprocessed, especially in cases where pretreatment may be needed before reprocessing, or where the enrichment is not high enough to make reprocessing attractive. Some fuels may be canistered, while others may require special means of disposal. The major categories covered in this chapter include HTGR spent fuel from the Fort St. Vrain and Peach Bottom-1 reactors, research and test reactor fuels, and miscellaneous fuels, and wastes generated from the decommissioning of facilities.« less

Flight Data Entry, Descent, and Landing (EDL) Repository

NASA Technical Reports Server (NTRS)

Martinez, Elmain M.; Winterhalter, Daniel

2012-01-01

Dr. Daniel Winterhalter, NASA Engineering and Safety Center Chief Engineer at the Jet Propulsion Laboratory, requested the NASA Engineering and Safety Center sponsor a 3-year effort to collect entry, descent, and landing material and to establish a NASA-wide archive to serve the material. The principle focus of this task was to identify entry, descent, and landing repository material that was at risk of being permanently lost due to damage, decay, and undocumented storage. To provide NASA-wide access to this material, a web-based digital archive was created. This document contains the outcome of the effort.

Software aspects of the Geant4 validation repository

NASA Astrophysics Data System (ADS)

Dotti, Andrea; Wenzel, Hans; Elvira, Daniel; Genser, Krzysztof; Yarba, Julia; Carminati, Federico; Folger, Gunter; Konstantinov, Dmitri; Pokorski, Witold; Ribon, Alberto

2017-10-01

The Geant4, GeantV and GENIE collaborations regularly perform validation and regression tests for simulation results. DoSSiER (Database of Scientific Simulation and Experimental Results) is being developed as a central repository to store the simulation results as well as the experimental data used for validation. DoSSiER is easily accessible via a web application. In addition, a web service allows for programmatic access to the repository to extract records in JSON or XML exchange formats. In this article, we describe the functionality and the current status of various components of DoSSiER as well as the technology choices we made.

Software Aspects of the Geant4 Validation Repository

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dotti, Andrea; Wenzel, Hans; Elvira, Daniel

2016-01-01

The Geant4, GeantV and GENIE collaborations regularly perform validation and regression tests for simulation results. DoSSiER (Database of Scientic Simulation and Experimental Results) is being developed as a central repository to store the simulation results as well as the experimental data used for validation. DoSSiER is easily accessible via a web application. In addition, a web service allows for programmatic access to the repository to extract records in JSON or XML exchange formats. In this article, we describe the functionality and the current status of various components of DoSSiER as well as the technology choices we made.

A Repository of Codes of Ethics and Technical Standards in Health Informatics

PubMed Central

Zaïane, Osmar R.

2014-01-01

We present a searchable repository of codes of ethics and standards in health informatics. It is built using state-of-the-art search algorithms and technologies. The repository will be potentially beneficial for public health practitioners, researchers, and software developers in finding and comparing ethics topics of interest. Public health clinics, clinicians, and researchers can use the repository platform as a one-stop reference for various ethics codes and standards. In addition, the repository interface is built for easy navigation, fast search, and side-by-side comparative reading of documents. Our selection criteria for codes and standards are two-fold; firstly, to maintain intellectual property rights, we index only codes and standards freely available on the internet. Secondly, major international, regional, and national health informatics bodies across the globe are surveyed with the aim of understanding the landscape in this domain. We also look at prevalent technical standards in health informatics from major bodies such as the International Standards Organization (ISO) and the U. S. Food and Drug Administration (FDA). Our repository contains codes of ethics from the International Medical Informatics Association (IMIA), the iHealth Coalition (iHC), the American Health Information Management Association (AHIMA), the Australasian College of Health Informatics (ACHI), the British Computer Society (BCS), and the UK Council for Health Informatics Professions (UKCHIP), with room for adding more in the future. Our major contribution is enhancing the findability of codes and standards related to health informatics ethics by compilation and unified access through the health informatics ethics repository. PMID:25422725

Feasibility of an International Multiple Sclerosis Rehabilitation Data Repository

PubMed Central

Bradford, Elissa Held; Baert, Ilse; Finlayson, Marcia; Feys, Peter

2018-01-01

Abstract Background: Multiple sclerosis (MS) rehabilitation evidence is limited due to methodological factors, which may be addressed by a data repository. We describe the perceived challenges of, motivators for, interest in participating in, and key features of an international MS rehabilitation data repository. Methods: A multimethod sequential investigation was performed with the results of two focus groups, using nominal group technique, and study aims informing the development of an online questionnaire. Percentage agreement and key quotations illustrated questionnaire findings. Subgroup comparisons were made between clinicians and researchers and between participants in North America and Europe. Results: Rehabilitation professionals from 25 countries participated (focus groups: n = 21; questionnaire: n = 166). The top ten challenges (C) and motivators (M) identified by the focus groups were database control/management (C); ethical/legal concerns (C); data quality (C); time, effort, and cost (C); best practice (M); uniformity (C); sustainability (C); deeper analysis (M); collaboration (M); and identifying research needs (M). Percentage agreement with questionnaire statements regarding challenges to, motivators for, interest in, and key features of a successful repository was at least 80%, 85%, 72%, and 83%, respectively, across each group of statements. Questionnaire subgroup analysis revealed a few differences (P < .05), including that clinicians more strongly identified with improving best practice as a motivator. Conclusions: Findings support clinician and researcher interest in and potential for success of an international MS rehabilitation data repository if prioritized challenges and motivators are addressed and key features are included. PMID:29507539

Implementing and Sustaining Data Lifecycle best Practices: a Framework for Researchers and Repositories

NASA Astrophysics Data System (ADS)

Stall, S.

2016-02-01

Emerging data management mandates in conjunction with cross-domain international interoperability are posing new challenges for researchers and repositories. Domain repositories are serving in this critical, growing role monitoring and leading data management standards and capability within their own repository and working on mappings between repositories internationally. Leading research institutions and companies will also be important as they develop and expand data curation efforts. This landscape poses a number of challenges for developing and ensuring the use of best practices in curating research data, enabling discovery, elevating quality across diverse repositories, and helping researchers collect and organize it through the full data life cycle. This multidimensional challenge will continue to grow in complexity. The American Geophysical Union (AGU) is developing two programs to help researchers and data repositories develop and elevate best practices and address these challenges. The goal is to provide tools for the researchers and repositories, whether domain, institutional, or other, that improve performance throughout the data lifecycle across the Earth and space science community. For scientists and researchers, AGU is developing courses around handling data that can lead toward a certification in geoscience data management. Course materials will cover metadata management and collection, data analysis, integration of data, and data presentation. The course topics are being finalized by the advisory board with the first one planned to be available later this year. AGU is also developing a program aimed at helping data repositories, large and small, domain-specific to general, assess and improve data management practices. AGU has partnered with the CMMI® Institute to adapt their Data Management Maturity (DMM)SM framework within the Earth and space sciences. A data management assessment using the DMMSM involves identifying accomplishments and

A Climate Statistics Tool and Data Repository

NASA Astrophysics Data System (ADS)

Wang, J.; Kotamarthi, V. R.; Kuiper, J. A.; Orr, A.

2017-12-01

Researchers at Argonne National Laboratory and collaborating organizations have generated regional scale, dynamically downscaled climate model output using Weather Research and Forecasting (WRF) version 3.3.1 at a 12km horizontal spatial resolution over much of North America. The WRF model is driven by boundary conditions obtained from three independent global scale climate models and two different future greenhouse gas emission scenarios, named representative concentration pathways (RCPs). The repository of results has a temporal resolution of three hours for all the simulations, includes more than 50 variables, is stored in Network Common Data Form (NetCDF) files, and the data volume is nearly 600Tb. A condensed 800Gb set of NetCDF files were made for selected variables most useful for climate-related planning, including daily precipitation, relative humidity, solar radiation, maximum temperature, minimum temperature, and wind. The WRF model simulations are conducted for three 10-year time periods (1995-2004, 2045-2054, and 2085-2094), and two future scenarios RCP4.5 and RCP8.5). An open-source tool was coded using Python 2.7.8 and ESRI ArcGIS 10.3.1 programming libraries to parse the NetCDF files, compute summary statistics, and output results as GIS layers. Eight sets of summary statistics were generated as examples for the contiguous U.S. states and much of Alaska, including number of days over 90°F, number of days with a heat index over 90°F, heat waves, monthly and annual precipitation, drought, extreme precipitation, multi-model averages, and model bias. This paper will provide an overview of the project to generate the main and condensed data repositories, describe the Python tool and how to use it, present the GIS results of the computed examples, and discuss some of the ways they can be used for planning. The condensed climate data, Python tool, computed GIS results, and documentation of the work are shared on the Internet.

10 CFR 960.3-4 - Environmental impacts.

Code of Federal Regulations, 2010 CFR

2010-01-01

... REPOSITORY Implementation Guidelines § 960.3-4 Environmental impacts. Environmental impacts shall be considered by the DOE throughout the site characterization, site selection, and repository development..., during site characterization and repository construction, operation, closure, and decommissioning. ...

The French Geological Repository Project Cigeo - 12023

DOE Office of Scientific and Technical Information (OSTI.GOV)

Harman, Alain; Labalette, Thibaud; Dupuis, Marie-Claude

The French Agency for Radioactive Waste Management, ANDRA, was launched by law in 1991 to perform and develop the research programme for managing high level and intermediate level long-lived radioactive waste generated by the French nuclear fleet. After a 15-year intensive research programme, including the study of alternative solutions, an overall review and assessment of the results was organized, including a national public debate. As a result, the Parliament passed a Planning Act on radioactive waste management in 2006. Commissioning of a geological repository by 2025 was one of the most important decisions taken at that time. To reach thismore » goal, a license application must be submitted and reviewed by the competent authorities by 2015. A detailed review and consultation process is, as well, defined in the Planning Act. Beside the legal framework the project needs to progress on two fronts. The first one is on siting. A significant milestone was reached in 2009 with the definition of a defined area to locate the underground repository facilities. This area was approved in March 2010 by the Government, after having collected the opinions and positions of all the interested parties, at both National and local levels. A new phase of dialogue with local players began to refine the implementation scenarios of surface facilities. The final site selection will be approved after a public debate planned for 2013. The second one is the industrial organization, planning and costing. The industrial project of this geological repository was called Cigeo (Centre Industriel de Stockage Geologique). Given the amount of work to be done to comply with the given time framework, a detailed organization with well-defined milestones must be set-up. Cigeo will be a specific nuclear facility, built and operated underground for over a hundred years. The consequence of this long duration is that the development of the repository facilities will take place in successive

10 CFR Appendix II to Part 960 - NRC and EPA Requirements for Preclosure Repository Performance

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false NRC and EPA Requirements for Preclosure Repository... SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Pt. 960, App. II Appendix II to Part 960—NRC and EPA Requirements for Preclosure Repository Performance Under proposed 40 CFR part 191, subpart A...

10 CFR Appendix I to Part 960 - NRC and EPA Requirements for Postclosure Repository Performance

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false NRC and EPA Requirements for Postclosure Repository... SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Pt. 960, App. I Appendix I to Part 960—NRC and EPA Requirements for Postclosure Repository Performance Under proposed 40 CFR part 191, subpart B...

Embracing the Future: Embedding Digital Repositories in Higher Education Institutions. Research Brief

ERIC Educational Resources Information Center

Hoorens, Stijn; van Dijk, Lidia Villalba; van Stolk, Christian

2009-01-01

This briefing paper captures the key findings and recommendations of a study commissioned by the Joint Information Systems Committee on aspects of the strategic commitment of institutions to repository sustainability. This project, labelled EMBRACE (EMBedding Repositories And Consortial Enhancement), is aimed at enhancing the functionality,…

A Semantically Enabled Metadata Repository for Solar Irradiance Data Products

NASA Astrophysics Data System (ADS)

Wilson, A.; Cox, M.; Lindholm, D. M.; Nadiadi, I.; Traver, T.

2014-12-01

The Laboratory for Atmospheric and Space Physics, LASP, has been conducting research in Atmospheric and Space science for over 60 years, and providing the associated data products to the public. LASP has a long history, in particular, of making space-based measurements of the solar irradiance, which serves as crucial input to several areas of scientific research, including solar-terrestrial interactions, atmospheric, and climate. LISIRD, the LASP Interactive Solar Irradiance Data Center, serves these datasets to the public, including solar spectral irradiance (SSI) and total solar irradiance (TSI) data. The LASP extended metadata repository, LEMR, is a database of information about the datasets served by LASP, such as parameters, uncertainties, temporal and spectral ranges, current version, alerts, etc. It serves as the definitive, single source of truth for that information. The database is populated with information garnered via web forms and automated processes. Dataset owners keep the information current and verified for datasets under their purview. This information can be pulled dynamically for many purposes. Web sites such as LISIRD can include this information in web page content as it is rendered, ensuring users get current, accurate information. It can also be pulled to create metadata records in various metadata formats, such as SPASE (for heliophysics) and ISO 19115. Once these records are be made available to the appropriate registries, our data will be discoverable by users coming in via those organizations. The database is implemented as a RDF triplestore, a collection of instances of subject-object-predicate data entities identifiable with a URI. This capability coupled with SPARQL over HTTP read access enables semantic queries over the repository contents. To create the repository we leveraged VIVO, an open source semantic web application, to manage and create new ontologies and populate repository content. A variety of ontologies were used in

SATORI: a system for ontology-guided visual exploration of biomedical data repositories.

PubMed

Lekschas, Fritz; Gehlenborg, Nils

2018-04-01

The ever-increasing number of biomedical datasets provides tremendous opportunities for re-use but current data repositories provide limited means of exploration apart from text-based search. Ontological metadata annotations provide context by semantically relating datasets. Visualizing this rich network of relationships can improve the explorability of large data repositories and help researchers find datasets of interest. We developed SATORI-an integrative search and visual exploration interface for the exploration of biomedical data repositories. The design is informed by a requirements analysis through a series of semi-structured interviews. We evaluated the implementation of SATORI in a field study on a real-world data collection. SATORI enables researchers to seamlessly search, browse and semantically query data repositories via two visualizations that are highly interconnected with a powerful search interface. SATORI is an open-source web application, which is freely available at http://satori.refinery-platform.org and integrated into the Refinery Platform. nils@hms.harvard.edu. Supplementary data are available at Bioinformatics online.

Performance Assessment of a Generic Repository in Bedded Salt for DOE-Managed Nuclear Waste

NASA Astrophysics Data System (ADS)

Stein, E. R.; Sevougian, S. D.; Hammond, G. E.; Frederick, J. M.; Mariner, P. E.

2016-12-01

A mined repository in salt is one of the concepts under consideration for disposal of DOE-managed defense-related spent nuclear fuel (SNF) and high level waste (HLW). Bedded salt is a favorable medium for disposal of nuclear waste due to its low permeability, high thermal conductivity, and ability to self-heal. Sandia's Generic Disposal System Analysis framework is used to assess the ability of a generic repository in bedded salt to isolate radionuclides from the biosphere. The performance assessment considers multiple waste types of varying thermal load and radionuclide inventory, the engineered barrier system comprising the waste packages, backfill, and emplacement drifts, and the natural barrier system formed by a bedded salt deposit and the overlying sedimentary sequence (including an aquifer). The model simulates disposal of nearly the entire inventory of DOE-managed, defense-related SNF (excluding Naval SNF) and HLW in a half-symmetry domain containing approximately 6 million grid cells. Grid refinement captures the detail of 25,200 individual waste packages in 180 disposal panels, associated access halls, and 4 shafts connecting the land surface to the repository. Equations describing coupled heat and fluid flow and reactive transport are solved numerically with PFLOTRAN, a massively parallel flow and transport code. Simulated processes include heat conduction and convection, waste package failure, waste form dissolution, radioactive decay and ingrowth, sorption, solubility limits, advection, dispersion, and diffusion. Simulations are run to 1 million years, and radionuclide concentrations are observed within an aquifer at a point approximately 4 kilometers downgradient of the repository. The software package DAKOTA is used to sample likely ranges of input parameters including waste form dissolution rates and properties of engineered and natural materials in order to quantify uncertainty in predicted concentrations and sensitivity to input parameters. Sandia

76 FR 14028 - Center for Devices and Radiological Health 510(k) Implementation: Online Repository of Medical...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-15

...] Center for Devices and Radiological Health 510(k) Implementation: Online Repository of Medical Device... public meeting entitled ``510(k) Implementation: Discussion of an Online Repository of Medical Device... establish an online public repository of medical device labeling and strategies for displaying device...

10 CFR 60.132 - Additional design criteria for surface facilities in the geologic repository operations area.

Code of Federal Regulations, 2010 CFR

2010-01-01

... geologic repository operations area. 60.132 Section 60.132 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Technical Criteria Design Criteria for the Geologic Repository Operations Area § 60.132 Additional design criteria for surface facilities in...

Making proteomics data accessible and reusable: Current state of proteomics databases and repositories

PubMed Central

Perez-Riverol, Yasset; Alpi, Emanuele; Wang, Rui; Hermjakob, Henning; Vizcaíno, Juan Antonio

2015-01-01

Compared to other data-intensive disciplines such as genomics, public deposition and storage of MS-based proteomics, data are still less developed due to, among other reasons, the inherent complexity of the data and the variety of data types and experimental workflows. In order to address this need, several public repositories for MS proteomics experiments have been developed, each with different purposes in mind. The most established resources are the Global Proteome Machine Database (GPMDB), PeptideAtlas, and the PRIDE database. Additionally, there are other useful (in many cases recently developed) resources such as ProteomicsDB, Mass Spectrometry Interactive Virtual Environment (MassIVE), Chorus, MaxQB, PeptideAtlas SRM Experiment Library (PASSEL), Model Organism Protein Expression Database (MOPED), and the Human Proteinpedia. In addition, the ProteomeXchange consortium has been recently developed to enable better integration of public repositories and the coordinated sharing of proteomics information, maximizing its benefit to the scientific community. Here, we will review each of the major proteomics resources independently and some tools that enable the integration, mining and reuse of the data. We will also discuss some of the major challenges and current pitfalls in the integration and sharing of the data. PMID:25158685

US nuclear repository in jeopardy

NASA Astrophysics Data System (ADS)

Gwynne, Peter

2009-04-01

Physicists have expressed uneasiness about the future of nuclear-waste storage in the US after President Barack Obama's administration proposed slashing funds for a long-planned repository at Yucca Mountain in Nevada. If approved by Congress, the cuts seem likely to spell the death knell of the project, which has been in the works since 1987 and has so far cost the government 9.5bn.

Repository-based software engineering program

NASA Technical Reports Server (NTRS)

Wilson, James

1992-01-01

The activities performed during September 1992 in support of Tasks 01 and 02 of the Repository-Based Software Engineering Program are outlined. The recommendations and implementation strategy defined at the September 9-10 meeting of the Reuse Acquisition Action Team (RAAT) are attached along with the viewgraphs and reference information presented at the Institute for Defense Analyses brief on legal and patent issues related to software reuse.

Corrosion behavior of Alloy 22 in heated surface test conditions in simulated Yucca Mountain Nuclear Repository environment

NASA Astrophysics Data System (ADS)

Badwe, Sunil

In the nuclear repository conditions, the nuclear waste package wall surfaces will be at elevated temperatures because of the heat generated by fission reactions within the waste. It is anticipated that the ground water may contain varying levels of anions such as chloride, nitrate, sulfate picked up from the rocks. The ground waters could seep through the rock faults and drip on to the waste packages. The dripped water will evaporate due to the heat from the nuclear waste leaving behind concentrated brine which eventually becomes dry salt deposit. The multi-ionic salts in the ground water are expected to be hygroscopic in nature. The next drop of water falling at the same place or the humidity in the repository will transform the hygroscopic salt deposit into a more concentrated brine. This cycle will continue for years and eventually a potentially corrosive brine will be formed on the waste package surface. Hence the waste package surface goes through the alternate wet-dry cycles. These conditions indicate that the concentration and pH of the environment in the repository vary considerably. The conventional corrosion tests hardly simulate these varying environmental conditions. Hence there has been a need to develop an electrochemical test that could closely simulate the anticipated repository conditions stated above. In this research, a new electrochemical method, called as Heated Surface Corrosion testing (HSCT) has been devised and tested. In the conventional testing the electrolyte is heated and in HSCT the working electrode is heated. The present study employs the temperature of 80°C which may be one of the temperatures of the waste package surface. The new HSCT was validated by testing stainless steel type 304. The HSCT was observed to be more aggressive than the conventional tests. Initiation of pitting of SS 304 in chloride solution (pH 3) occurred at much shorter exposure times in the HSCT condition than the exposure time required for pitting in

Vector Adaptive/Predictive Encoding Of Speech

NASA Technical Reports Server (NTRS)

Chen, Juin-Hwey; Gersho, Allen

1989-01-01

Vector adaptive/predictive technique for digital encoding of speech signals yields decoded speech of very good quality after transmission at coding rate of 9.6 kb/s and of reasonably good quality at 4.8 kb/s. Requires 3 to 4 million multiplications and additions per second. Combines advantages of adaptive/predictive coding, and code-excited linear prediction, yielding speech of high quality but requires 600 million multiplications and additions per second at encoding rate of 4.8 kb/s. Vector adaptive/predictive coding technique bridges gaps in performance and complexity between adaptive/predictive coding and code-excited linear prediction.

ROSA P : The National Transportation Library’s Repository and Open Science Access Portal

DOT National Transportation Integrated Search

2018-01-01

The National Transportation Library (NTL) was founded as an all-digital repository of US DOT research reports, technical publications and data products. NTLs primary public offering is ROSA P, the Repository and Open Science Access Portal. An open...

Institutional Repositories, Open Access, and Scholarly Communication: A Study of Conflicting Paradigms

ERIC Educational Resources Information Center

Cullen, Rowena; Chawner, Brenda

2011-01-01

The Open Access movement of the past decade, and institutional repositories developed by universities and academic libraries as a part of that movement, have openly challenged the traditional scholarly communication system. This article examines the growth of repositories around the world, and summarizes a growing body of evidence of the response…

Experiences in improving the state of the practice in verification and validation of knowledge-based systems

NASA Technical Reports Server (NTRS)

Culbert, Chris; French, Scott W.; Hamilton, David

1994-01-01

Knowledge-based systems (KBS's) are in general use in a wide variety of domains, both commercial and government. As reliance on these types of systems grows, the need to assess their quality and validity reaches critical importance. As with any software, the reliability of a KBS can be directly attributed to the application of disciplined programming and testing practices throughout the development life-cycle. However, there are some essential differences between conventional software and KBSs, both in construction and use. The identification of these differences affect the verification and validation (V&V) process and the development of techniques to handle them. The recognition of these differences is the basis of considerable on-going research in this field. For the past three years IBM (Federal Systems Company - Houston) and the Software Technology Branch (STB) of NASA/Johnson Space Center have been working to improve the 'state of the practice' in V&V of Knowledge-based systems. This work was motivated by the need to maintain NASA's ability to produce high quality software while taking advantage of new KBS technology. To date, the primary accomplishment has been the development and teaching of a four-day workshop on KBS V&V. With the hope of improving the impact of these workshops, we also worked directly with NASA KBS projects to employ concepts taught in the workshop. This paper describes two projects that were part of this effort. In addition to describing each project, this paper describes problems encountered and solutions proposed in each case, with particular emphasis on implications for transferring KBS V&V technology beyond the NASA domain.

10 CFR 960.5-2-3 - Meteorology.

Code of Federal Regulations, 2010 CFR

2010-01-01

... REPOSITORY Preclosure Guidelines Preclosure Radiological Safety § 960.5-2-3 Meteorology. (a) Qualifying condition. The site shall be located such that expected meteorological conditions during repository.... Prevailing meteorological conditions such that any radioactive releases to the atmosphere during repository...

Basic repository source term and data sheet report: Lavender Canyon

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1988-01-01

This report is one of a series describing studies undertaken in support of the US Department of Energy Civilian Radioactive Waste Management (CRWM) Program. This study contains the derivation of values for environmental source terms and resources consumed for a CRWM repository. Estimates include heavy construction equipment; support equipment; shaft-sinking equipment; transportation equipment; and consumption of fuel, water, electricity, and natural gas. Data are presented for construction and operation at an assumed site in Lavender Canyon, Utah. 3 refs; 6 tabs.

A performance goal-based seismic design philosophy for waste repository facilities

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hossain, Q.A.

1994-12-31

A performance goal-based seismic design philosophy, compatible with DOE`s present natural phenomena hazards mitigation and {open_quotes}graded approach{close_quotes} philosophy, has been proposed for high level nuclear waste repository facilities. The rationale, evolution, and the desirable features of this method have been described. Why and how the method should and can be applied to the design of a repository facility are also discussed.

AASG State Geothermal Data Repository for the National Geothermal Data System.

DOE Office of Scientific and Technical Information (OSTI.GOV)

2012-01-01

This Drupal metadata and documents capture and management system is a repository, used for maintenance of metadata which describe resources contributed to the AASG State Geothermal Data System. The repository also provides an archive for files that are not hosted by the agency contributing the resource. Data from all 50 state geological surveys is represented here, and is contributed in turn to the National Geothermal Data System.

Proteomics data repositories: Providing a safe haven for your data and acting as a springboard for further research

PubMed Central

Vizcaíno, Juan Antonio; Foster, Joseph M.; Martens, Lennart

2010-01-01

Despite the fact that data deposition is not a generalised fact yet in the field of proteomics, several mass spectrometry (MS) based proteomics repositories are publicly available for the scientific community. The main existing resources are: the Global Proteome Machine Database (GPMDB), PeptideAtlas, the PRoteomics IDEntifications database (PRIDE), Tranche, and NCBI Peptidome. In this review the capabilities of each of these will be described, paying special attention to four key properties: data types stored, applicable data submission strategies, supported formats, and available data mining and visualization tools. Additionally, the data contents from model organisms will be enumerated for each resource. There are other valuable smaller and/or more specialized repositories but they will not be covered in this review. Finally, the concept behind the ProteomeXchange consortium, a collaborative effort among the main resources in the field, will be introduced. PMID:20615486

DSA-WDS Common Requirements: Developing a New Core Data Repository Certification

NASA Astrophysics Data System (ADS)

Minster, J. B. H.; Edmunds, R.; L'Hours, H.; Mokrane, M.; Rickards, L.

2016-12-01

The Data Seal of Approval (DSA) and the International Council for Science - World Data System (ICSU-WDS) have both developed minimally intensive core certification standards whereby digital repositories supply evidence that they are trustworthy and have a long-term outlook. Both DSA and WDS applicants have found core certification to be beneficial: building stakeholder confidence, enhancing the repository's reputation, and demonstrating that it is following good practices; as well as stimulating the repository to focus on processes and procedures, thereby achieving ever higher levels of professionalism over time.The DSA and WDS core certifications evolved independently serving initially different communities but both initiatives are multidisciplinary with catalogues of criteria and review procedures based on the same principles. Hence, to realize efficiencies, simplify assessment options, stimulate more certifications, and increase impact on the community, the Repository Audit and Certification DSA-WDS Partnership Working Group (WG) was established under the umbrella of the Research Data Alliance (RDA). The WG conducted a side-by-side analysis of both frameworks to unify the wording and criteria, ultimately leading to a harmonized Catalogue of Common Requirements for core certification of repositories—as well as a set of Common Procedures for their assessment.This presentation will focus on the collaborative effort by DSA and WDS to establish (1) a testbed comprising DSA and WDS certified data repositories to validate both the new Catalogue and Procedures, and (2) a joint Certification Board towards their practical implementation. We will describe:• The purpose and methodology of the testbed, including selection of repositories to be assessed against the common standard.• The results of the testbed, with an in-depth look at some of the comments received and issues highlighted.• General insights gained from evaluating the testbed results, the subsequent

Concept document of the repository-based software engineering program: A constructive appraisal

NASA Technical Reports Server (NTRS)

1992-01-01

A constructive appraisal of the Concept Document of the Repository-Based Software Engineering Program is provided. The Concept Document is designed to provide an overview of the Repository-Based Software Engineering (RBSE) Program. The Document should be brief and provide the context for reading subsequent requirements and product specifications. That is, all requirements to be developed should be traceable to the Concept Document. Applied Expertise's analysis of the Document was directed toward assuring that: (1) the Executive Summary provides a clear, concise, and comprehensive overview of the Concept (rewrite as necessary); (2) the sections of the Document make best use of the NASA 'Data Item Description' for concept documents; (3) the information contained in the Document provides a foundation for subsequent requirements; and (4) the document adequately: identifies the problem being addressed; articulates RBSE's specific role; specifies the unique aspects of the program; and identifies the nature and extent of the program's users.

Statistical sensitivity analysis of a simple nuclear waste repository model

NASA Astrophysics Data System (ADS)

Ronen, Y.; Lucius, J. L.; Blow, E. M.

1980-06-01

A preliminary step in a comprehensive sensitivity analysis of the modeling of a nuclear waste repository. The purpose of the complete analysis is to determine which modeling parameters and physical data are most important in determining key design performance criteria and then to obtain the uncertainty in the design for safety considerations. The theory for a statistical screening design methodology is developed for later use in the overall program. The theory was applied to the test case of determining the relative importance of the sensitivity of near field temperature distribution in a single level salt repository to modeling parameters. The exact values of the sensitivities to these physical and modeling parameters were then obtained using direct methods of recalculation. The sensitivity coefficients found to be important for the sample problem were thermal loading, distance between the spent fuel canisters and their radius. Other important parameters were those related to salt properties at a point of interest in the repository.

Research on wild relatives of fruit and nut crops at the Davis repository

USDA-ARS?s Scientific Manuscript database

The USDA germplasm repository in Davis is responsible for acquiring, conserving and distributing a broad spectrum of diversity of subtropical and temperate fruit and nut species germplasm to stakeholders around the world. Currently the repository holds over 7000 accessions of germplasm including Act...

Institutional Repositories in the UK: What Can the Google User Find There?

ERIC Educational Resources Information Center

Markland, Margaret

2006-01-01

This study investigates the efficiency of the Google search engine at retrieving items from 26 UK Institutional Repositories, covering a wide range of subject areas. One item is chosen from each repository and four searches are carried out: two keyword searches and two full title searches, each using both Google and then Google Scholar. A further…

Fukushima Daiichi Information Repository FY13 Status

DOE Office of Scientific and Technical Information (OSTI.GOV)

Smith, Curtis; Phelan, Cherie; Schwieder, Dave

The accident at the Fukushima Daiichi nuclear power station in Japan is one of the most serious in commercial nuclear power plant operating history. Much will be learned that may be applicable to the U.S. reactor fleet, nuclear fuel cycle facilities, and supporting systems, and the international reactor fleet. For example, lessons from Fukushima Daiichi may be applied to emergency response planning, reactor operator training, accident scenario modeling, human factors engineering, radiation protection, and accident mitigation; as well as influence U.S. policies towards the nuclear fuel cycle including power generation, and spent fuel storage, reprocessing, and disposal. This document describesmore » the database used to establish a centralized information repository to store and manage the Fukushima data that has been gathered. The data is stored in a secured (password protected and encrypted) repository that is searchable and available to researchers at diverse locations.« less

DESM: portal for microbial knowledge exploration systems.

PubMed

Salhi, Adil; Essack, Magbubah; Radovanovic, Aleksandar; Marchand, Benoit; Bougouffa, Salim; Antunes, Andre; Simoes, Marta Filipa; Lafi, Feras F; Motwalli, Olaa A; Bokhari, Ameerah; Malas, Tariq; Amoudi, Soha Al; Othum, Ghofran; Allam, Intikhab; Mineta, Katsuhiko; Gao, Xin; Hoehndorf, Robert; C Archer, John A; Gojobori, Takashi; Bajic, Vladimir B

2016-01-04

Microorganisms produce an enormous variety of chemical compounds. It is of general interest for microbiology and biotechnology researchers to have means to explore information about molecular and genetic basis of functioning of different microorganisms and their ability for bioproduction. To enable such exploration, we compiled 45 topic-specific knowledgebases (KBs) accessible through DESM portal (www.cbrc.kaust.edu.sa/desm). The KBs contain information derived through text-mining of PubMed information and complemented by information data-mined from various other resources (e.g. ChEBI, Entrez Gene, GO, KOBAS, KEGG, UniPathways, BioGrid). All PubMed records were indexed using 4,538,278 concepts from 29 dictionaries, with 1 638 986 records utilized in KBs. Concepts used are normalized whenever possible. Most of the KBs focus on a particular type of microbial activity, such as production of biocatalysts or nutraceuticals. Others are focused on specific categories of microorganisms, e.g. streptomyces or cyanobacteria. KBs are all structured in a uniform manner and have a standardized user interface. Information exploration is enabled through various searches. Users can explore statistically most significant concepts or pairs of concepts, generate hypotheses, create interactive networks of associated concepts and export results. We believe DESM will be a useful complement to the existing resources to benefit microbiology and biotechnology research. © The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research.

17 CFR 49.3 - Procedures for registration.

Code of Federal Regulations, 2014 CFR

2014-04-01

... if the Commission finds that such swap data repository is appropriately organized, and has the...) SWAP DATA REPOSITORIES § 49.3 Procedures for registration. (a) Application procedures. (1) An applicant, person or entity desiring to be registered as a swap data repository shall file electronically an...

75 FR 8701 - Notice of Settlement Agreement Pertaining to Construction of a Waste Repository on the Settlors...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-25

... Construction of a Waste Repository on the Settlors' Property Pursuant to the Comprehensive Environmental... a Settlement Agreement pertaining to Construction of a Waste Repository on Settlor's Property... waste repository on the property by resolving, liability the settling party might otherwise incur under...

Geologic, geochemical rock mechanics and hydrologic characteristics of candidate repository horizons

NASA Astrophysics Data System (ADS)

Long, P. E.; Apted, M. J.; Spane, F. A., Jr.; Kim, K.

1982-09-01

The feasibility of constructing a nuclear waste repository in basalt (NWRB) on the Hanford Site is determined. Studies conducted indicate feasibility and performance requirements are within a significant safety margin. The two most promising candidate repository horizons for an NWRB are the middle Sentinel Bluffs and the Umtanum flows. Both of these flows are laterally continuous and have thicknesses of competent rock adequate to accommodate a repository. Significant geologic differences between the two flows are their depth, total thickness, and variability of flow top thickness. These differences are considered in selection of one of the two flows for breakout from an exploratory shaft. The geochemical characteristics of both the middle Sentinel Bluffs flow and the Umtanum flow favor long term isolation of radionuclides by providing an environment in which canister corrosion rates and solubility of many radionuclide bearing solids is relatively low.

An Optimal Centralized Carbon Dioxide Repository for Florida, USA

PubMed Central

Poiencot, Brandon; Brown, Christopher

2011-01-01

For over a decade, the United States Department of Energy, and engineers, geologists, and scientists from all over the world have investigated the potential for reducing atmospheric carbon emissions through carbon sequestration. Numerous reports exist analyzing the potential for sequestering carbon dioxide at various sites around the globe, but none have identified the potential for a statewide system in Florida, USA. In 2005, 83% of Florida’s electrical energy was produced by natural gas, coal, or oil (e.g., fossil fuels), from power plants spread across the state. In addition, only limited research has been completed on evaluating optimal pipeline transportation networks to centralized carbon dioxide repositories. This paper describes the feasibility and preliminary locations for an optimal centralized Florida-wide carbon sequestration repository. Linear programming optimization modeling is used to plan and route an idealized pipeline network to existing Florida power plants. Further analysis of the subsurface geology in these general locations will provide insight into the suitability of the subsurface conditions and the available capacity for carbon sequestration at selected possible repository sites. The identification of the most favorable site(s) is also presented. PMID:21695024

An optimal centralized carbon dioxide repository for Florida, USA.

PubMed

Poiencot, Brandon; Brown, Christopher

2011-04-01

For over a decade, the United States Department of Energy, and engineers, geologists, and scientists from all over the world have investigated the potential for reducing atmospheric carbon emissions through carbon sequestration. Numerous reports exist analyzing the potential for sequestering carbon dioxide at various sites around the globe, but none have identified the potential for a statewide system in Florida, USA. In 2005, 83% of Florida's electrical energy was produced by natural gas, coal, or oil (e.g., fossil fuels), from power plants spread across the state. In addition, only limited research has been completed on evaluating optimal pipeline transportation networks to centralized carbon dioxide repositories. This paper describes the feasibility and preliminary locations for an optimal centralized Florida-wide carbon sequestration repository. Linear programming optimization modeling is used to plan and route an idealized pipeline network to existing Florida power plants. Further analysis of the subsurface geology in these general locations will provide insight into the suitability of the subsurface conditions and the available capacity for carbon sequestration at selected possible repository sites. The identification of the most favorable site(s) is also presented.

European Space Software Repository ESSR

NASA Astrophysics Data System (ADS)

Livschitz, Jakob; Blommestijn, Robert

2016-08-01

The paper and presentation will present the status of the ESSR (European Space Software Repository), see [1]. It will describe the development phases, outline the web portal functionality and explain the process steps behind. Not only the front-end but also the back-end will be discussed.The ESSR web portal went live ESA internal on May 15th, 2015 and live world-wide September 19th, 2015. Currently the ESSR is in operations.

NCI Expands Repository of Cancer Research Models

Cancer.gov

NCI is expanding its Patient-Derived Models Repository (PDMR), which generates and distributes models like patient-derived xenografts and organoids. In this Cancer Currents Q&A with Drs. Yvonne Evrard and James Doroshow, learn how the expansion can help cancer researchers make more rapid progress.

Rolling Deck to Repository (R2R): Technical Design - Experiences and Lessons (Invited)

NASA Astrophysics Data System (ADS)

Arko, R. A.; Carbotte, S. M.; Miller, S. P.; Chandler, C. L.; Ferrini, V.; Stocks, K.; Maffei, A. R.; Smith, S. R.; Bourassa, M. A.; McLean, S. J.; Alberts, J. C.

2009-12-01

The NSF-funded Rolling Deck to Repository (R2R) project envisions the academic research fleet as an integrated global observing system, with routine “underway” sensor data flowing directly from research vessels to a central shore-side repository. It is a complex endeavor involving many stakeholders - technicians at sea, data managers on shore, ship schedulers, clearance officers, funding agencies, National Data Centers, data synthesis projects, the science community, and the public - working toward a common goal of acquiring, documenting, archiving, evaluating, and disseminating high-quality scientific data. The technical design for R2R is guided by several key principles: 1) The data pipeline is modular, so that initial stages (e.g. inventory and review of data shipments, posting of catalog records and track maps) may proceed routinely for every cruise, while later stages (e.g. quality assessment and production of file-level metadata) may proceed at different rates for different data types; 2) Cruise documentation (e.g. sailing orders, review/release of data inventories, vessel profiles) is gathered primarily via an authenticated Web portal, linked with the UNOLS scheduling database to synchronize vocabularies and eliminate redundancies; and 3) Every data set will be documented and delivered to the appropriate National Data Center for long-term archiving and dissemination after proprietary holds are cleared, while R2R maintains a master cruise catalog that links all the data sets together. This design accommodates the diversity of instrument types, data volumes, and shipment schedules among fleet operators. During its pilot development period, R2R has solicited feedback at community workshops, UNOLS meetings, and conference presentations, including fleet-wide surveys of current practices and instrument inventories. Several vessel operators began submitting cruise data and documentation during the pilot, providing a test bed for database development and Web

Characterization of Discharge Areas of Radionuclides Originating From Nuclear Waste Repositories

NASA Astrophysics Data System (ADS)

Marklund, L.; Xu, S.; Worman, A.

2009-05-01

If leakages in nuclear waste repositories located in crystalline bedrock arise, radionuclides will reach the biosphere and cause a risk of radiological impact. The extent of the radiological impact depends on in which landscape elements the radionuclides emerge. In this study, we investigate if there are certain landscape elements that generally will act as discharge areas for radionuclides leaking from subsurface deposits. We also characterize the typical properties that distinguish these areas from others. In humid regions, landscape topography is the most important driving force for groundwater flow. Because groundwater is the main transporting agent for migrating radionuclides, the topography will determine the flowpaths of leaking radionuclides. How topography and heterogeneities in the subsurface affect the discharge distribution of the radionuclides is therefore an important scope of this study. To address these issues, we developed a 3-D transport model. Our analyses are based on site-specific data from two different areas in Sweden, Forsmark, Uppland, and Oskarshamn, Småland. The Swedish Nuclear Waste Management Company (SKB) has selected these two areas as candidate areas for a deep repository of nuclear waste and the areas are currently subject to site investigations. Our results suggest that there are hot-spots in the landscape i.e. areas with high probability of receiving large amounts of radionuclides from a leaking repository of nuclear waste. The hot-spots concentrate in the sea, streams, lakes and wetlands. All these elements are found at lower elevations in the landscape. This pattern is mostly determined by the landscape topography and the locations of fracture zones. There is a relationship between fracture zones and topography, and therefore the importance of the topography for the discharge area distribution is not contradicted by the heterogeneity in the bedrock. The varieties of landscape elements which have potential for receiving

10 CFR 960.3-2 - Siting process.

Code of Federal Regulations, 2010 CFR

2010-01-01

... REPOSITORY Implementation Guidelines § 960.3-2 Siting process. The siting process begins with site screening... first repository before the enactment of the Act, and the identification of such sites was made after... identification of potentially acceptable sites for the second and subsequent repositories shall be conducted in...

Using OAI-PMH and METS for Exporting Metadata and Digital Objects between Repositories

ERIC Educational Resources Information Center

Bell, Jonathan; Lewis, Stuart

2006-01-01

Purpose: To examine the relationship between deposit of electronic theses in institutional and archival repositories. Specifically the paper considers the automated export of theses for deposit in the archival repository in continuation of the existing arrangement in Wales for paper-based theses. Design/methodology/approach: The paper presents a…

Preliminary evaluation of solution-mining intrusion into a salt-dome repository

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1981-06-01

This report is the product of the work of an ONWI task force to evaluate inadvertant human intrusion into a salt dome repository by solution mining. It summarizes the work in the following areas: a general review of the levels of defense that could reduce both the likelihood and potential consequences of human intrusion into a salt dome repository; evaluation of a hypothetical intrusion scenario and its consequences; recommendation for further studies. The conclusions of this task force report can be summarized as follows: (1) it is not possible at present to establish with certainty that solution mining is crediblemore » as a human-intrusion event. The likelihood of such an intrusion will depend on the effectiveness of the preventive measures; (2) an example analysis based on the realistic approach is presented in this report; it concluded that the radiological consequences are strongly dependent upon the mode of radionuclide release from the waste form, time after emplacement, package design, impurities in the host salt, the amount of a repository intercepted, the solution mining cavity form, the length of time over which solution mining occurs, the proportion of contaminated salt source for human consumption compared to other sources, and the method of salt purification for culinary purposes; (3) worst case scenarios done by other studies suggest considerable potential for exposures to man while preliminary evaluations of more realistic cases suggest significantly reduced potential consequences. Mathematical model applications to process systems, guided by more advanced assumptions about human intrusion into geomedia, will shed more light on the potential for concerns and the degree to which mitigative measures will be required.« less

YUCCA MOUNTAIN: Earth-Science Issues at a Geologic Repository for High-Level Nuclear Waste

NASA Astrophysics Data System (ADS)

Long, Jane C. S.

2004-05-01

The nation has over 40,000 metric tonnes (MT) of nuclear waste destined for disposal in a geologic repository at Yucca Mountain. In this review, we highlight some of the important geoscience issues associated with the project and place them in the context of the process by which a final decision on Yucca Mountain will be made. The issues include understanding how water could infiltrate the repository, corrode the canisters, dissolve the waste, and transport it to the biosphere during a 10,000-year compliance period in a region, the Basin and Range province, that is known for seismic and volcanic activity. Although the site is considered to be "dry," a considerable amount of water is present as pore waters and as structural water in zeolites. The geochemical environment is oxidizing, and the present repository design will maintain temperatures at greater than 100°C for thousands of years. Geoscientists in this project are challenged to make unprecedented predictions about coupled thermal, hydrologic, mechanical, and geochemical processes governing the future behavior of the repository and to conduct research in a regulatory and legal environment that requires a quantitative analysis of repository performance.

A Prototype Performance Assessment Model for Generic Deep Borehole Repository for High-Level Nuclear Waste - 12132

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lee, Joon H.; Arnold, Bill W.; Swift, Peter N.

2012-07-01

A deep borehole repository is one of the four geologic disposal system options currently under study by the U.S. DOE to support the development of a long-term strategy for geologic disposal of commercial used nuclear fuel (UNF) and high-level radioactive waste (HLW). The immediate goal of the generic deep borehole repository study is to develop the necessary modeling tools to evaluate and improve the understanding of the repository system response and processes relevant to long-term disposal of UNF and HLW in a deep borehole. A prototype performance assessment model for a generic deep borehole repository has been developed using themore » approach for a mined geological repository. The preliminary results from the simplified deep borehole generic repository performance assessment indicate that soluble, non-sorbing (or weakly sorbing) fission product radionuclides, such as I-129, Se-79 and Cl-36, are the likely major dose contributors, and that the annual radiation doses to hypothetical future humans associated with those releases may be extremely small. While much work needs to be done to validate the model assumptions and parameters, these preliminary results highlight the importance of a robust seal design in assuring long-term isolation, and suggest that deep boreholes may be a viable alternative to mined repositories for disposal of both HLW and UNF. (authors)« less

Building and Using Digital Repository Certifications across Science

NASA Astrophysics Data System (ADS)

McIntosh, L.

2017-12-01

When scientific recommendations are made based upon research, the quality and integrity of the data should be rigorous enough to verify claims and in a trusted location. Key to ensuring the transparency and verifiability of research, reproducibility hinges not only on the availability of the documentation, analyses, and data, but the ongoing accessibility and viability of the files and documents, enhanced through a process of curation. The Research Data Alliance (RDA) is an international, community-driven, action-oriented, virtual organization committed to enabling the open sharing of data by building social and technical bridges. Within the RDA, multiple groups are working on consensus-building around the certification of digital repositories across scientific domains. For this section of the panel, we will discuss the work to date on repository certification from this RDA perspective.

Multimedia data repository for the World Wide Web

NASA Astrophysics Data System (ADS)

Chen, Ken; Lu, Dajin; Xu, Duanyi

1998-08-01

This paper introduces the design and implementation of a Multimedia Data Repository served as a multimedia information system, which provides users a Web accessible, platform independent interface to query, browse, and retrieve multimedia data such as images, graphics, audio, video from a large multimedia data repository. By integrating the multimedia DBMS, in which the textual information and samples of the multimedia data is organized and stored, and Web server together into the Microsoft ActiveX Server Framework, users can access the DBMS and query the information by simply using a Web browser at the client-side. The original multimedia data can then be located and transmitted through the Internet from the tertiary storage device, a 400 CDROM optical jukebox at the server-side, to the client-side for further use.

Opinion: Why we need a centralized repository for isotopic data

USGS Publications Warehouse

Pauli, Jonathan N.; Newsome, Seth D.; Cook, Joseph A.; Harrod, Chris; Steffan, Shawn A.; Baker, Christopher J. O.; Ben-David, Merav; Bloom, David; Bowen, Gabriel J.; Cerling, Thure E.; Cicero, Carla; Cook, Craig; Dohm, Michelle; Dharampal, Prarthana S.; Graves, Gary; Gropp, Robert; Hobson, Keith A.; Jordan, Chris; MacFadden, Bruce; Pilaar Birch, Suzanne; Poelen, Jorrit; Ratnasingham, Sujeevan; Russell, Laura; Stricker, Craig A.; Uhen, Mark D.; Yarnes, Christopher T.; Hayden, Brian

2017-01-01

Stable isotopes encode and integrate the origin of matter; thus, their analysis offers tremendous potential to address questions across diverse scientific disciplines (1, 2). Indeed, the broad applicability of stable isotopes, coupled with advancements in high-throughput analysis, have created a scientific field that is growing exponentially, and generating data at a rate paralleling the explosive rise of DNA sequencing and genomics (3). Centralized data repositories, such as GenBank, have become increasingly important as a means for archiving information, and “Big Data” analytics of these resources are revolutionizing science and everyday life.

Making proteomics data accessible and reusable: current state of proteomics databases and repositories.

PubMed

Perez-Riverol, Yasset; Alpi, Emanuele; Wang, Rui; Hermjakob, Henning; Vizcaíno, Juan Antonio

2015-03-01

Compared to other data-intensive disciplines such as genomics, public deposition and storage of MS-based proteomics, data are still less developed due to, among other reasons, the inherent complexity of the data and the variety of data types and experimental workflows. In order to address this need, several public repositories for MS proteomics experiments have been developed, each with different purposes in mind. The most established resources are the Global Proteome Machine Database (GPMDB), PeptideAtlas, and the PRIDE database. Additionally, there are other useful (in many cases recently developed) resources such as ProteomicsDB, Mass Spectrometry Interactive Virtual Environment (MassIVE), Chorus, MaxQB, PeptideAtlas SRM Experiment Library (PASSEL), Model Organism Protein Expression Database (MOPED), and the Human Proteinpedia. In addition, the ProteomeXchange consortium has been recently developed to enable better integration of public repositories and the coordinated sharing of proteomics information, maximizing its benefit to the scientific community. Here, we will review each of the major proteomics resources independently and some tools that enable the integration, mining and reuse of the data. We will also discuss some of the major challenges and current pitfalls in the integration and sharing of the data. © 2014 The Authors. PROTEOMICS published by Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

2nd NUTRITION w/Repository collection period

NASA Image and Video Library

2011-10-04

ISS029-E-015096 (4 Oct. 2011) --- In the International Space Station?s Kibo laboratory, NASA astronaut Mike Fossum, Expedition 29 commander, prepares to insert samples into a Minus Eighty Laboratory Freezer for ISS (MELFI-1) dewar tray for the second NUTRITION w/Repository collection period.

2nd NUTRITION w/Repository collection period

NASA Image and Video Library

2011-10-04

ISS029-E-015110 (4 Oct. 2011) --- In the International Space Station?s Kibo laboratory, NASA astronaut Mike Fossum, Expedition 29 commander, inserts a dewar tray of samples into the Minus Eighty Laboratory Freezer for ISS (MELFI-1) for the second NUTRITION w/Repository collection period.

A Novel Navigation Paradigm for XML Repositories.

ERIC Educational Resources Information Center

Azagury, Alain; Factor, Michael E.; Maarek, Yoelle S.; Mandler, Benny

2002-01-01

Discusses data exchange over the Internet and describes the architecture and implementation of an XML document repository that promotes a navigation paradigm for XML documents based on content and context. Topics include information retrieval and semistructured documents; and file systems as information storage infrastructure, particularly XMLFS.…

HEPData: a repository for high energy physics data

NASA Astrophysics Data System (ADS)

Maguire, Eamonn; Heinrich, Lukas; Watt, Graeme

2017-10-01

The Durham High Energy Physics Database (HEPData) has been built up over the past four decades as a unique open-access repository for scattering data from experimental particle physics papers. It comprises data points underlying several thousand publications. Over the last two years, the HEPData software has been completely rewritten using modern computing technologies as an overlay on the Invenio v3 digital library framework. The software is open source with the new site available at https://hepdata.net now replacing the previous site at http://hepdata.cedar.ac.uk. In this write-up, we describe the development of the new site and explain some of the advantages it offers over the previous platform.

A proposed application programming interface for a physical volume repository

NASA Technical Reports Server (NTRS)

Jones, Merritt; Williams, Joel; Wrenn, Richard

1996-01-01

The IEEE Storage System Standards Working Group (SSSWG) has developed the Reference Model for Open Storage Systems Interconnection, Mass Storage System Reference Model Version 5. This document, provides the framework for a series of standards for application and user interfaces to open storage systems. More recently, the SSSWG has been developing Application Programming Interfaces (APIs) for the individual components defined by the model. The API for the Physical Volume Repository is the most fully developed, but work is being done on APIs for the Physical Volume Library and for the Mover also. The SSSWG meets every other month, and meetings are open to all interested parties. The Physical Volume Repository (PVR) is responsible for managing the storage of removable media cartridges and for mounting and dismounting these cartridges onto drives. This document describes a model which defines a Physical Volume Repository, and gives a brief summary of the Application Programming Interface (API) which the IEEE Storage Systems Standards Working Group (SSSWG) is proposing as the standard interface for the PVR.

A Python library for FAIRer access and deposition to the Metabolomics Workbench Data Repository.

PubMed

Smelter, Andrey; Moseley, Hunter N B

2018-01-01

The Metabolomics Workbench Data Repository is a public repository of mass spectrometry and nuclear magnetic resonance data and metadata derived from a wide variety of metabolomics studies. The data and metadata for each study is deposited, stored, and accessed via files in the domain-specific 'mwTab' flat file format. In order to improve the accessibility, reusability, and interoperability of the data and metadata stored in 'mwTab' formatted files, we implemented a Python library and package. This Python package, named 'mwtab', is a parser for the domain-specific 'mwTab' flat file format, which provides facilities for reading, accessing, and writing 'mwTab' formatted files. Furthermore, the package provides facilities to validate both the format and required metadata elements of a given 'mwTab' formatted file. In order to develop the 'mwtab' package we used the official 'mwTab' format specification. We used Git version control along with Python unit-testing framework as well as continuous integration service to run those tests on multiple versions of Python. Package documentation was developed using sphinx documentation generator. The 'mwtab' package provides both Python programmatic library interfaces and command-line interfaces for reading, writing, and validating 'mwTab' formatted files. Data and associated metadata are stored within Python dictionary- and list-based data structures, enabling straightforward, 'pythonic' access and manipulation of data and metadata. Also, the package provides facilities to convert 'mwTab' files into a JSON formatted equivalent, enabling easy reusability of the data by all modern programming languages that implement JSON parsers. The 'mwtab' package implements its metadata validation functionality based on a pre-defined JSON schema that can be easily specialized for specific types of metabolomics studies. The library also provides a command-line interface for interconversion between 'mwTab' and JSONized formats in raw text and a

OWLing Clinical Data Repositories With the Ontology Web Language

PubMed Central

Pastor, Xavier; Lozano, Esther

2014-01-01

Background The health sciences are based upon information. Clinical information is usually stored and managed by physicians with precarious tools, such as spreadsheets. The biomedical domain is more complex than other domains that have adopted information and communication technologies as pervasive business tools. Moreover, medicine continuously changes its corpus of knowledge because of new discoveries and the rearrangements in the relationships among concepts. This scenario makes it especially difficult to offer good tools to answer the professional needs of researchers and constitutes a barrier that needs innovation to discover useful solutions. Objective The objective was to design and implement a framework for the development of clinical data repositories, capable of facing the continuous change in the biomedicine domain and minimizing the technical knowledge required from final users. Methods We combined knowledge management tools and methodologies with relational technology. We present an ontology-based approach that is flexible and efficient for dealing with complexity and change, integrated with a solid relational storage and a Web graphical user interface. Results Onto Clinical Research Forms (OntoCRF) is a framework for the definition, modeling, and instantiation of data repositories. It does not need any database design or programming. All required information to define a new project is explicitly stated in ontologies. Moreover, the user interface is built automatically on the fly as Web pages, whereas data are stored in a generic repository. This allows for immediate deployment and population of the database as well as instant online availability of any modification. Conclusions OntoCRF is a complete framework to build data repositories with a solid relational storage. Driven by ontologies, OntoCRF is more flexible and efficient to deal with complexity and change than traditional systems and does not require very skilled technical people facilitating

OWLing Clinical Data Repositories With the Ontology Web Language.

PubMed

Lozano-Rubí, Raimundo; Pastor, Xavier; Lozano, Esther

2014-08-01

The health sciences are based upon information. Clinical information is usually stored and managed by physicians with precarious tools, such as spreadsheets. The biomedical domain is more complex than other domains that have adopted information and communication technologies as pervasive business tools. Moreover, medicine continuously changes its corpus of knowledge because of new discoveries and the rearrangements in the relationships among concepts. This scenario makes it especially difficult to offer good tools to answer the professional needs of researchers and constitutes a barrier that needs innovation to discover useful solutions. The objective was to design and implement a framework for the development of clinical data repositories, capable of facing the continuous change in the biomedicine domain and minimizing the technical knowledge required from final users. We combined knowledge management tools and methodologies with relational technology. We present an ontology-based approach that is flexible and efficient for dealing with complexity and change, integrated with a solid relational storage and a Web graphical user interface. Onto Clinical Research Forms (OntoCRF) is a framework for the definition, modeling, and instantiation of data repositories. It does not need any database design or programming. All required information to define a new project is explicitly stated in ontologies. Moreover, the user interface is built automatically on the fly as Web pages, whereas data are stored in a generic repository. This allows for immediate deployment and population of the database as well as instant online availability of any modification. OntoCRF is a complete framework to build data repositories with a solid relational storage. Driven by ontologies, OntoCRF is more flexible and efficient to deal with complexity and change than traditional systems and does not require very skilled technical people facilitating the engineering of clinical software systems.

Type 2 and type 3 burst theory

NASA Technical Reports Server (NTRS)

Smith, D. F.

1973-01-01

The present state of the theory of type 3 bursts is reviewed by dividing the problem into the exciting agency, radiation source, and propagation of radiation between the source and the observer. In-situ measurements indicate that the excitors are electron streams of energy about 40 keV which are continuously relaxing. An investigation of neutralization of an electron stream indicates that n sub s is much less than 100,000 n sub e, where n sub s is the stream density and n sub e the coronal electron density. In situ observations are consistent with this result. An analysis of propagation of electrons in the current sheets of coronal streamers shows that such propagation at heights greater than 1 solar radius is impossible. The mechanisms for radiation are reviewed; it is shown that fundamental radiation at high frequencies (approximately 100 MHz) is highly beamed in the radial direction and that near the earth second harmonic radiation must be dominant. Because of beaming of the fundamental at high frequencies, it can often be quite weak near the limb so that the second harmonic is dominant. In considering propagation to the observer, the results of scattering of radiation are discussed. The present state of the theory of type 2 bursts is reviewed in the same manner as type 3 bursts.

Collaborative Learning Utilizing a Domain-Based Shared Data Repository to Enhance Learning Outcomes

ERIC Educational Resources Information Center

Lubliner, David; Widmeyer, George; Deek, Fadi P.

2009-01-01

The objective of this study was to determine whether there was a quantifiable improvement in learning outcomes by integrating course materials in a 4-year baccalaureate program, utilizing a knowledge repository with a conceptual map that spans a discipline. Two new models were developed to provide the framework for this knowledge repository. A…

Radiation release at the nation's only operating deep geological repository--an independent monitoring perspective.

PubMed

Thakur, P; Ballard, S; Hardy, R

2014-11-04

Recent incidents at the nation's only operating deep geologic nuclear waste repository, the Waste Isolation Pilot Plant (WIPP), resulted in the release of americium and plutonium from one or more defense-related transuranic (TRU) waste containers into the environment. WIPP is a U.S. Department of Energy mined geologic repository that has been in operation since March, 1999. Over 85,000 m3 of waste in various vented payload containers have been emplaced in the repository. The primary radionuclides within the disposed waste are 239+240Pu and 241Am, which account for more than 99% of the total TRU radioactivity disposed and scheduled for disposal in the repository. For the first time in its 15 years of operation, there was an airborne radiation release from the WIPP at approximately 11:30 PM Mountain Standard Time (MST) on Friday, February 14, 2014. The radiation release was likely caused by a chemical reaction inside a TRU waste drum that contained nitrate salts and organic sorbent materials. In a recent news release, DOE announced that photos taken of the waste underground showed evidence of heat and gas pressure resulting in a deformed lid, in material expelled through that deformation, and in melted plastic and rubber and polyethylene in the vicinity of that drum. Recent entries into underground Panel 7 have confirmed that at least one waste drum containing a nitrate salt bearing waste stream from Los Alamos National Laboratory was breached underground and was the most likely source of the release. Further investigation is underway to determine if other containers contributed to the release. Air monitoring across the WIPP site intensified following the first reports of radiation detection underground to ascertain whether or not there were releases to the ground surface. Independent analytical results of air filters from sampling stations on and near the WIPP facility have been released by us at the Carlsbad Environmental Monitoring & Research Center and confirmed

The Belgian repository of fundamental atomic data and stellar spectra (BRASS). I. Cross-matching atomic databases of astrophysical interest

NASA Astrophysics Data System (ADS)

Laverick, M.; Lobel, A.; Merle, T.; Royer, P.; Martayan, C.; David, M.; Hensberge, H.; Thienpont, E.

2018-04-01

Context. Fundamental atomic parameters, such as oscillator strengths, play a key role in modelling and understanding the chemical composition of stars in the Universe. Despite the significant work underway to produce these parameters for many astrophysically important ions, uncertainties in these parameters remain large and can propagate throughout the entire field of astronomy. Aims: The Belgian repository of fundamental atomic data and stellar spectra (BRASS) aims to provide the largest systematic and homogeneous quality assessment of atomic data to date in terms of wavelength, atomic and stellar parameter coverage. To prepare for it, we first compiled multiple literature occurrences of many individual atomic transitions, from several atomic databases of astrophysical interest, and assessed their agreement. In a second step synthetic spectra will be compared against extremely high-quality observed spectra, for a large number of BAFGK spectral type stars, in order to critically evaluate the atomic data of a large number of important stellar lines. Methods: Several atomic repositories were searched and their data retrieved and formatted in a consistent manner. Data entries from all repositories were cross-matched against our initial BRASS atomic line list to find multiple occurrences of the same transition. Where possible we used a new non-parametric cross-match depending only on electronic configurations and total angular momentum values. We also checked for duplicate entries of the same physical transition, within each retrieved repository, using the non-parametric cross-match. Results: We report on the number of cross-matched transitions for each repository and compare their fundamental atomic parameters. We find differences in log(gf) values of up to 2 dex or more. We also find and report that 2% of our line list and Vienna atomic line database retrievals are composed of duplicate transitions. Finally we provide a number of examples of atomic spectral lines

Geoengineering properties of potential repository units at Yucca Mountain, southern Nevada

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tillerson, J.R.; Nimick, F.B.

1984-12-01

The Nevada Nuclear Waste Storage Investigations (NNWSI) Project is currently evaluating volcanic tuffs at the Yucca Mountain site, located on and adjacent to the Nevada Test Site, for possible use as a host rock for a radioactive waste repository. The behavior of tuff as an engineering material must be understood to design, license, construct, and operate a repository. Geoengineering evaluations and measurements are being made to develop confidence in both the analysis techniques for thermal, mechanical, and hydrothermal effects and the supporting data base of rock properties. The analysis techniques and the data base are currently used for repository design,more » waste package design, and performance assessment analyses. This report documents the data base of geoengineering properties used in the analyses that aided the selection of the waste emplacement horizon and in analyses synopsized in the Environmental Assessment Report prepared for the Yucca Mountain site. The strategy used for the development of the data base relies primarily on data obtained in laboratory tests that are then confirmed in field tests. Average thermal and mechanical properties (and their anticipated variations) are presented. Based upon these data, analyses completed to date, and previous excavation experience in tuff, it is anticipated that existing mining technology can be used to develop stable underground openings and that repository operations can be carried out safely.« less

Correcting names of bacteria deposited in National Microbial Repositories: an analysed sequence data necessary for taxonomic re-categorization of misclassified bacteria-ONE example, genus Lysinibacillus.

PubMed

Rekadwad, Bhagwan N; Gonzalez, Juan M

2017-08-01

A report on 16S rRNA gene sequence re-analysis and digitalization is presented using Lysinibacillus species (one example) deposited in National Microbial Repositories in India. Lysinibacillus species 16S rRNA gene sequences were digitalized to provide quick response (QR) codes, Chaose Game Representation (CGR) and Frequency of Chaose Game Representation (FCGR). GC percentage, phylogenetic analysis, and principal component analysis (PCA) are tools used for the differentiation and reclassification of the strains under investigation. The seven reasons supporting the statements made by us as misclassified Lysinibacillus species deposited in National Microbial Depositories are given in this paper. Based on seven reasons, bacteria deposited in National Microbial Repositories such as Lysinibacillus and many other needs reanalyses for their exact identity. Leaves of identity with type strains of related species shows difference 2 to 8 % suggesting that reclassification is needed to correctly assign species names to the analyzed Lysinibacillus strains available in National Microbial Repositories.

Method for storing spent nuclear fuel in repositories

DOEpatents

Schweitzer, Donald G.; Sastre, Cesar; Winsche, Warren

1981-01-01

A method for storing radioactive spent fuel in repositories containing sulfur as the storage medium is disclosed. Sulfur is non-corrosive and not subject to radiation damage. Thus, storage periods of up to 100 years are possible.

Method for storing spent nuclear fuel in repositories

DOEpatents

Schweitzer, D.G.; Sastre, C.; Winsche, W.

A method for storing radioactive spent fuel in repositories containing sulfur as the storage medium is disclosed. Sulfur is non-corrosive and not subject to radiation damage. Thus, storage periods of up to 100 years are possible.

Personal Spaces in Public Repositories as a Facilitator for Open Educational Resource Usage

ERIC Educational Resources Information Center

Cohen, Anat; Reisman, Sorel; Sperling, Barbra Bied

2015-01-01

Learning object repositories are a shared, open and public space; however, the possibility and ability of personal expression in an open, global, public space is crucial. The aim of this study is to explore personal spaces in a big learning object repository as a facilitator for adoption of Open Educational Resources (OER) into teaching practices…

Basic repository environmental assessment design basis, Lavender Canyon site

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1988-01-01

This study examines the engineering factors and costs associated with the construction, operation, and decommissioning of a high-level nuclear waste repository in salt in the Paradox Basin in Lavender Canyon, Utah. The study assumes a repository capacity of 36,000 metric tons of heavy metal (MTHM) of unreprocessed spent fuel and 36,000 MTHM of commercial high-level reprocessing waste, along with 7020 canisters of defense high-level reprocessing waste and associated quantities of remote- and contact-handled transuranic waste (TRU). With the exception of TRU, all the waste forms are placed in 300- to 1000-year-life carbon-steel waste packages in a collocated waste handling andmore » packaging facility (WHPF), which is also described. The construction, operation, and decommissioning of the proposed repository is estimated to cost approximately $5.51 billion. Costs include those for the collocated WHPP, engineering, and contingency, but exclude waste form assembly and shipment to the site and waste package fabrication and shipment to the site. These costs reflect the relative average wage rates of the region and the relatively sound nature of the salt at this site. Construction would require an estimated 7.75 years. Engineering factors and costs are not strongly influenced by environmental considerations. 51 refs., 24 figs., 20 tabs.« less

Airborne microorganisms cultivable on naturally ventilated document repositories of the National Archive of Cuba.

PubMed

Borrego, Sofía; Perdomo, Ivette

2016-02-01

The quality of the indoor air can provide very useful information for the artwork conservation. The aim of the study was to evaluate the microbial concentration inside six document repositories of the National Archive of the Republic of Cuba in two months of 1 year. The repositories are large, high, and have a natural cross-ventilation system. The microbial sampling was done in July 2010 (summer or rainy month) and February 2011 (winter or dry month) using the SAS Super 100 biocollector at 100 L/min. An appropriate selective culture media were used to isolate fungi and bacteria. A high total microbial concentration on the north side of the building in two studied months was observed. The fungal concentrations were significantly higher in July 2010 in all repositories, while the bacterial concentrations were significantly higher mostly in February 2011 only in repositories located on the first and second floor of the building. Eight fungal genera in the indoor air of all environments were isolated. Regardless of the side of the analyzed building, Penicillium, Aspergillus, and Cladosporium were the predominant genera. Aspergillus flavus and Aspergillus niger were the species isolated in almost all of the analyzed repositories in the studied months. Gram-positive bacteria prevailed among bacterial groups isolated from indoor air repositories, and some percentages corresponded to the genera Bacillus and Streptomyces. In Cuba, the temperature and relative humidity are high during the whole year but the natural ventilation plays an important role in retarding microbial growth on materials.

Source term evaluation model for high-level radioactive waste repository with decay chain build-up.

PubMed

Chopra, Manish; Sunny, Faby; Oza, R B

2016-09-18

A source term model based on two-component leach flux concept is developed for a high-level radioactive waste repository. The long-lived radionuclides associated with high-level waste may give rise to the build-up of activity because of radioactive decay chains. The ingrowths of progeny are incorporated in the model using Bateman decay chain build-up equations. The model is applied to different radionuclides present in the high-level radioactive waste, which form a part of decay chains (4n to 4n + 3 series), and the activity of the parent and daughter radionuclides leaching out of the waste matrix is estimated. Two cases are considered: one when only parent is present initially in the waste and another where daughters are also initially present in the waste matrix. The incorporation of in situ production of daughter radionuclides in the source is important to carry out realistic estimates. It is shown that the inclusion of decay chain build-up is essential to avoid underestimation of the radiological impact assessment of the repository. The model can be a useful tool for evaluating the source term of the radionuclide transport models used for the radiological impact assessment of high-level radioactive waste repositories.

Post-metamorphic brecciation in type 3 ordinary chondrites

NASA Technical Reports Server (NTRS)

Scott, E. R. D.; Mccoy, T. J.; Keil, K.

1993-01-01

Type 3.1-3.9 ordinary chondrites can be divided into two kinds: those in which the compositions of chondrule silicates are entirely consistent with metamorphism of type 3.0 material, and those in which the computational heterogeneity appears to be too extreme for in situ metamorphism. We present petrologic data for three LL3 chondrites of the second kind--Ngawi, ALH A77278 (both type 3.6), and Hamlet (type 3.9)--and compare these data with results for the first kind of LL3-4 chondrites. Given that chondrules form in the nebula and that metamorphic equilibration occurs in asteroids, our new data imply that Ngawi, A77278, Hamlet, and many other type 3 ordinary chondrites are post-metamorphic breccias containing materials with diverse metamorphic histories; they are not metamorphic rocks or special kinds of 'primitive breccias.' We infer also that metamorphism to type 3.1-3.9 levels produces very friable material that is easily remixed into breccias and lithified by mild shock. Thus, petrologic types and subtypes of chondrites indicate the mean metamorphic history of the ingredients, not the thermal history of the rock. The metamorphic history of individual type 1 or 2 porphyritic chondrules in type 3 breccias is best derived from olivine and pyroxene analyses and the data of McCoy et al. for unbrecciated chondrites. The new chondrule classification schemes of Sears, DeHart et al., appears to provide less information about the original state and metamorphic history of individual porphyritic chondrules and should not replace existing classification schemes.

Post-metamorphic brecciation in type 3 ordinary chondrites

NASA Astrophysics Data System (ADS)

Scott, E. R. D.; McCoy, T. J.; Keil, K.

1993-03-01

Type 3.1-3.9 ordinary chondrites can be divided into two kinds: those in which the compositions of chondrule silicates are entirely consistent with metamorphism of type 3.0 material, and those in which the computational heterogeneity appears to be too extreme for in situ metamorphism. We present petrologic data for three LL3 chondrites of the second kind--Ngawi, ALH A77278 (both type 3.6), and Hamlet (type 3.9)--and compare these data with results for the first kind of LL3-4 chondrites. Given that chondrules form in the nebula and that metamorphic equilibration occurs in asteroids, our new data imply that Ngawi, A77278, Hamlet, and many other type 3 ordinary chondrites are post-metamorphic breccias containing materials with diverse metamorphic histories; they are not metamorphic rocks or special kinds of 'primitive breccias.' We infer also that metamorphism to type 3.1-3.9 levels produces very friable material that is easily remixed into breccias and lithified by mild shock. Thus, petrologic types and subtypes of chondrites indicate the mean metamorphic history of the ingredients, not the thermal history of the rock. The metamorphic history of individual type 1 or 2 porphyritic chondrules in type 3 breccias is best derived from olivine and pyroxene analyses and the data of McCoy et al. for unbrecciated chondrites. The new chondrule classification schemes of Sears, DeHart et al., appears to provide less information about the original state and metamorphic history of individual porphyritic chondrules and should not replace existing classification schemes.

Integrating XQuery-Enabled SCORM XML Metadata Repositories into an RDF-Based E-Learning P2P Network

ERIC Educational Resources Information Center

Qu, Changtao; Nejdl, Wolfgang

2004-01-01

Edutella is an RDF-based E-Learning P2P network that is aimed to accommodate heterogeneous learning resource metadata repositories in a P2P manner and further facilitate the exchange of metadata between these repositories based on RDF. Whereas Edutella provides RDF metadata repositories with a quite natural integration approach, XML metadata…

Knowledge based systems: A preliminary survey of selected issues and techniques

NASA Technical Reports Server (NTRS)

Dominick, Wayne D. (Editor); Kavi, Srinu

1984-01-01

It is only recently that research in Artificial Intelligence (AI) is accomplishing practical results. Most of these results can be attributed to the design and use of expert systems (or Knowledge-Based Systems, KBS) - problem-solving computer programs that can reach a level of performance comparable to that of a human expert in some specialized problem domain. But many computer systems designed to see images, hear sounds, and recognize speech are still in a fairly early stage of development. In this report, a preliminary survey of recent work in the KBS is reported, explaining KBS concepts and issues and techniques used to construct them. Application considerations to construct the KBS and potential KBS research areas are identified. A case study (MYCIN) of a KBS is also provided.

Research Students and the Loughborough Institutional Repository

ERIC Educational Resources Information Center

Pickton, Margaret; McKnight, Cliff

2006-01-01

This article investigates the potential role for research students in an institutional repository (IR). Face-to-face interviews with 34 research students at Loughborough University were carried out. Using a mixture of closed and open questions, the interviews explored the students' experiences and opinions of publishing, open access and the…

The preliminary design and feasibility study of the spent fuel and high level waste repository in the Czech Republic

DOE Office of Scientific and Technical Information (OSTI.GOV)

Valvoda, Z.; Holub, J.; Kucerka, M.

1996-12-31

In the year 1993, began the Program of Development of the Spent Fuel and High Level Waste Repository in the Conditions of the Czech Republic. During the first phase, the basic concept and structure of the Program has been developed, and the basic design criteria and requirements were prepared. In the conditions of the Czech Republic, only an underground repository in deep geological formation is acceptable. Expected depth is between 500 to 1000 meters and as host rock will be granites. A preliminary variant design study was realized in 1994, that analyzed the radioactive waste and spent fuel flow frommore » NPPs to the repository, various possibilities of transportation in accordance to the various concepts of spent fuel conditioning and transportation to the underground structures. Conditioning and encapsulation of spent fuel and/or radioactive waste is proposed on the repository site. Underground disposal structures are proposed at one underground floor. The repository will have reserve capacity for radioactive waste from NPPs decommissioning and for waste non acceptable to other repositories. Vertical disposal of unshielded canisters in boreholes and/or horizontal disposal of shielded canisters is studied. As the base term of the start up of the repository operation, the year 2035 has been established. From this date, a preliminary time schedule of the Project has been developed. A method of calculating leveled and discounted costs within the repository lifetime, for each of selected 5 variants, was used for economic calculations. Preliminary expected parametric costs of the repository are about 0,1 Kc ($0.004) per MWh, produced in the Czech NPPs. In 1995, the design and feasibility study has gone in more details to the technical concept of repository construction and proposed technologies, as well as to the operational phase of the repository. Paper will describe results of the 1995 design work and will present the program of the repository development in

Knowledge-based system V and V in the Space Station Freedom program

NASA Technical Reports Server (NTRS)

Kelley, Keith; Hamilton, David; Culbert, Chris

1992-01-01

Knowledge Based Systems (KBS's) are expected to be heavily used in the Space Station Freedom Program (SSFP). Although SSFP Verification and Validation (V&V) requirements are based on the latest state-of-the-practice in software engineering technology, they may be insufficient for Knowledge Based Systems (KBS's); it is widely stated that there are differences in both approach and execution between KBS V&V and conventional software V&V. In order to better understand this issue, we have surveyed and/or interviewed developers from sixty expert system projects in order to understand the differences and difficulties in KBS V&V. We have used this survey results to analyze the SSFP V&V requirements for conventional software in order to determine which specific requirements are inappropriate for KBS V&V and why they are inappropriate. Further work will result in a set of recommendations that can be used either as guidelines for applying conventional software V&V requirements to KBS's or as modifications to extend the existing SSFP conventional software V&V requirements to include KBS requirements. The results of this work are significant to many projects, in addition to SSFP, which will involve KBS's.

Geochemistry of rock units at the potential repository level, Yucca Mountain, Nevada

USGS Publications Warehouse

Peterman, Z.E.; Cloke, P.L.

2002-01-01

The compositional variability of the phenocryst-poor member of the 12.8 Ma Topopah Spring Tuff at the potential repository level was assessed by duplicate analysis of 20 core samples from the cross drift at Yucca Mountain, Nevada. Previous analyses of outcrop and core samples of the Topopah Spring Tuff showed that the phenocryst-poor rhyolite, which includes both lithophysal and nonlithophysal zones, is relatively uniform in composition. Analyses of rock samples from the cross drift, the first from the actual potential repository block, also indicate the chemical homogeneity of this unit excluding localized deposits of vapor-phase minerals and low-temperature calcite and opal in fractures, cavities, and faults. The possible influence of vapor-phase minerals and calcite and opal coatings on rock composition at a scale sufficiently large to incorporate these heterogeneously distributed deposits was evaluated and is considered to be relatively minor. Therefore, the composition of the phenocryst-poor member of the Topopah Spring Tuff is considered to be adequately represented by the analyses of samples from the cross drift. The mean composition as represented by the 10 most abundant oxides in wt. % or g/100 g is: SiO2, 76.29; Al2O3, 12.55; FeO, 0.14; Fe2O3, 0.97; MgO, 0.13; CaO, 0.50; Na2O, 3.52; K2O, 4.83; TiO2, 0.11; and MnO, 0.07. ?? 2002 Published by Elsevier Science Ltd.

36 CFR 79.9 - Standards to determine when a repository possesses the capability to provide adequate long-term...

Code of Federal Regulations, 2010 CFR

2010-07-01

... repository possesses the capability to provide adequate long-term curatorial services. 79.9 Section 79.9... FEDERALLY-OWNED AND ADMINISTERED ARCHAEOLOGICAL COLLECTIONS § 79.9 Standards to determine when a repository... shall determine that a repository has the capability to provide adequate long-term curatorial services...

Cold-blooded vertebrates at the proposed Reference Repository Location in southeastern Washington

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fitzner, R.E.

1988-01-01

The information in this interim report will be used to design future environmental monitoring plans and assess impacts related to Basalt Waste Isolation Project (BWIP) activities. New reports will be issued as more data become available. Five study locations were established to study cold-blooded vertebrates in the vicinity of the proposed Reference Repository Location. Four study sites were in shrub-dominated stands of vegetation; the other site was devoid of shrubs because of a range fire in 1984. The side-blotched lizard (Uta stansburiana), trapped in four of the five plots, was the only lizard species captured. It was not trapped inmore » the one plot dominated by spiny hopsage (Grayia spinosa) shrubs. It is uncertain whether the side-blotched lizard is absent from this particular vegetation type, or if the population is too low to have been detected in the relatively short time span of the investigation. Two species of snakes were captured, gopher snakes (Pituophis melanoleucus) and green racers (Coluber constrictor mormon). The number of snakes captured was too small to detect any distributional pattern in space or time. Studies are continuing. 4 refs., 9 figs., 3 tabs.« less

The SoRReL papers: Recent publications of the Software Reuse Repository Lab

NASA Technical Reports Server (NTRS)

Eichmann, David A. (Editor)

1992-01-01

The entire publication is presented of some of the papers recently published by the SoRReL. Some typical titles are as follows: Design of a Lattice-Based Faceted Classification System; A Hybrid Approach to Software Reuse Repository Retrieval; Selecting Reusable Components Using Algebraic Specifications; Neural Network-Based Retrieval from Reuse Repositories; and A Neural Net-Based Approach to Software Metrics.

Researcher-library collaborations: Data repositories as a service for researchers.

PubMed

Gordon, Andrew S; Millman, David S; Steiger, Lisa; Adolph, Karen E; Gilmore, Rick O

New interest has arisen in organizing, preserving, and sharing the raw materials-the data and metadata-that undergird the published products of research. Library and information scientists have valuable expertise to bring to bear in the effort to create larger, more diverse, and more widely used data repositories. However, for libraries to be maximally successful in providing the research data management and preservation services required of a successful data repository, librarians must work closely with researchers and learn about their data management workflows. Databrary is a data repository that is closely linked to the needs of a specific scholarly community-researchers who use video as a main source of data to study child development and learning. The project's success to date is a result of its focus on community outreach and providing services for scholarly communication, engaging institutional partners, offering services for data curation with the guidance of closely involved information professionals, and the creation of a strong technical infrastructure. Databrary plans to improve its curation tools that allow researchers to deposit their own data, enhance the user-facing feature set, increase integration with library systems, and implement strategies for long-term sustainability.

Workshop on development of radionuclide getters for the Yucca Mountain waste repository: proceedings.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Moore, Robert Charles; Lukens, Wayne W.

The proposed Yucca Mountain repository, located in southern Nevada, is to be the first facility for permanent disposal of spent reactor fuel and high-level radioactive waste in the United States. Total Systems Performance Assessment (TSPA) analysis has indicated that among the major radionuclides contributing to dose are technetium, iodine, and neptunium, all of which are highly mobile in the environment. Containment of these radionuclides within the repository is a priority for the Yucca Mountain Project (YMP). These proceedings review current research and technology efforts for sequestration of the radionuclides with a focus on technetium, iodine, and neptunium. This workshop alsomore » covered issues concerning the Yucca Mountain environment and getter characteristics required for potential placement into the repository.« less

Evaluation on radiation protection aspect and radiological risk at Mukim Belanja repository

NASA Astrophysics Data System (ADS)

Azmi, Siti Nur Aisyah; Kenoh, Hamiza; Majid, Amran Ab.

2016-01-01

Asian Rare Earth (ARE) is a locally incorporated company that operated a mineral processing operation to extract rare earth element. ARE has received much attention from the public since the beginning of their operation until the work of decommissioning and decontamination of the plant. Due to the existence of Naturally Occurring Radioactive Material (NORM) in the residue, the decommissioning and disposal was done by the company in collaboration with the Perak State Government and the Atomic Energy Licensing Board (AELB). The main objective of this study is to review the level of compliance of the existing Radiation Protection Regulations enforced by AELB particularly in the achievement of allowed exposure dose limit. The next objective was to study the impact of the construction of the Mukim Belanja Repository to workers and public. This study was conducted by analyzing documents that were issued and conducting the area monitoring using a Geiger Muller detector (GM) and Sodium Iodide (NaI(Tl)) survey meters. The measurements were made at 5 cm and 1 m from the ground surface at 27 measurement stations. The external doses measured were within the background levels of the surrounding area. The annual effective dose using the highest reading at 5 cm and 1 m from ground surface by GM detector was calculated to be 1.36 mSv/year and 1.21 mSv/year respectively. Whereas the annual effective dose using the highest reading at 5 cm and 1 m from ground surface by using NaI(Tl) detector was calculated to be 3.31 mSv/year and 2.83 mSv/year respectively. The calculated cancer risks from the study showed that the risk is small compared with the risks derived from natural radiation based on global annual radiation dose to humans. This study therefore indicated that the repository is able to constrain the dose exposure from the disposed NORM waste. The study also revealed that the construction of the repository has complied with all the rules and regulations subjected to it. The

17 CFR 49.3 - Procedures for registration.

Code of Federal Regulations, 2012 CFR

2012-04-01

... that such swap data repository is appropriately organized, and has the capacity: to ensure the prompt.... 49.3 Section 49.3 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION SWAP DATA... desiring to be registered as a swap data repository shall file electronically an application for...

17 CFR 49.3 - Procedures for registration.

Code of Federal Regulations, 2013 CFR

2013-04-01

... that such swap data repository is appropriately organized, and has the capacity: to ensure the prompt.... 49.3 Section 49.3 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION SWAP DATA... desiring to be registered as a swap data repository shall file electronically an application for...

22 CFR 51.3 - Types of passports.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Types of passports. 51.3 Section 51.3 Foreign Relations DEPARTMENT OF STATE NATIONALITY AND PASSPORTS PASSPORTS General § 51.3 Types of passports. (a) Regular passport. A regular passport is issued to a national of the United States. (b) Official passport...

22 CFR 51.3 - Types of passports.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Types of passports. 51.3 Section 51.3 Foreign Relations DEPARTMENT OF STATE NATIONALITY AND PASSPORTS PASSPORTS General § 51.3 Types of passports. (a) Regular passport. A regular passport is issued to a national of the United States. (b) Official passport...

22 CFR 51.3 - Types of passports.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Types of passports. 51.3 Section 51.3 Foreign Relations DEPARTMENT OF STATE NATIONALITY AND PASSPORTS PASSPORTS General § 51.3 Types of passports. (a) Regular passport. A regular passport is issued to a national of the United States. (b) Official passport...

22 CFR 51.3 - Types of passports.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Types of passports. 51.3 Section 51.3 Foreign Relations DEPARTMENT OF STATE NATIONALITY AND PASSPORTS PASSPORTS General § 51.3 Types of passports. (a) Regular passport. A regular passport is issued to a national of the United States. (b) Official passport...

22 CFR 51.3 - Types of passports.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Types of passports. 51.3 Section 51.3 Foreign Relations DEPARTMENT OF STATE NATIONALITY AND PASSPORTS PASSPORTS General § 51.3 Types of passports. (a) Regular passport. A regular passport is issued to a national of the United States. (b) Official passport...

Examining Data Repository Guidelines for Qualitative Data Sharing.

PubMed

Antes, Alison L; Walsh, Heidi A; Strait, Michelle; Hudson-Vitale, Cynthia R; DuBois, James M

2018-02-01

Qualitative data provide rich information on research questions in diverse fields. Recent calls for increased transparency and openness in research emphasize data sharing. However, qualitative data sharing has yet to become the norm internationally and is particularly uncommon in the United States. Guidance for archiving and secondary use of qualitative data is required for progress in this regard. In this study, we review the benefits and concerns associated with qualitative data sharing and then describe the results of a content analysis of guidelines from international repositories that archive qualitative data. A minority of repositories provide qualitative data sharing guidelines. Of the guidelines available, there is substantial variation in whether specific topics are addressed. Some topics, such as removing direct identifiers, are consistently addressed, while others, such as providing an anonymization log, are not. We discuss the implications of our study for education, best practices, and future research.

Limitations to the use of two-dimensional thermal modeling of a nuclear waste repository

DOE Office of Scientific and Technical Information (OSTI.GOV)

Davis, B.W.

1979-01-04

Thermal modeling of a nuclear waste repository is basic to most waste management predictive models. It is important that the modeling techniques accurately determine the time-dependent temperature distribution of the waste emplacement media. Recent modeling studies show that the time-dependent temperature distribution can be accurately modeled in the far-field using a 2-dimensional (2-D) planar numerical model; however, the near-field cannot be modeled accurately enough by either 2-D axisymmetric or 2-D planar numerical models for repositories in salt. The accuracy limits of 2-D modeling were defined by comparing results from 3-dimensional (3-D) TRUMP modeling with results from both 2-D axisymmetric andmore » 2-D planar. Both TRUMP and ADINAT were employed as modeling tools. Two-dimensional results from the finite element code, ADINAT were compared with 2-D results from the finite difference code, TRUMP; they showed almost perfect correspondence in the far-field. This result adds substantially to confidence in future use of ADINAT and its companion stress code ADINA for thermal stress analysis. ADINAT was found to be somewhat sensitive to time step and mesh aspect ratio. 13 figures, 4 tables.« less

Container Approval for the Disposal of Radioactive Waste with Negligible Heat Generation in the German Konrad Repository - 12148

DOE Office of Scientific and Technical Information (OSTI.GOV)

Voelzke, Holger; Nieslony, Gregor; Ellouz, Manel

Since the license for the Konrad repository was finally confirmed by legal decision in 2007, the Federal Institute for Radiation Protection (BfS) has been performing further planning and preparation work to prepare the repository for operation. Waste conditioning and packaging has been continued by different waste producers as the nuclear industry and federal research institutes on the basis of the official disposal requirements. The necessary prerequisites for this are approved containers as well as certified waste conditioning and packaging procedures. The Federal Institute for Materials Research and Testing (BAM) is responsible for container design testing and evaluation of quality assurancemore » measures on behalf of BfS under consideration of the Konrad disposal requirements. Besides assessing the container handling stability (stacking tests, handling loads), design testing procedures are performed that include fire tests (800 deg. C, 1 hour) and drop tests from different heights and drop orientations. This paper presents the current state of BAM design testing experiences about relevant container types (box shaped, cylindrical) made of steel sheets, ductile cast iron or concrete. It explains usual testing and evaluation methods which range from experimental testing to analytical and numerical calculations. Another focus has been laid on already existing containers and packages. The question arises as to how they can be evaluated properly especially with respect to lack of completeness of safety assessment and fabrication documentation. At present BAM works on numerous applications for container design testing for the Konrad repository. Some licensing procedures were successfully finished in the past and BfS certified several container types like steel sheet, concrete until cast iron containers which are now available for waste packaging for final disposal. However, large quantities of radioactive wastes had been placed into interim storage using containers

Accelerating research through reagent repositories: the genome editing example.

PubMed

Joung, J Keith; Voytas, Daniel F; Kamens, Joanne

2015-11-20

Keith Joung, Dan Voytas and Joanne Kamens share insights into how the genome editing field was advanced by early access to biological resources and the role in this process that plasmid repositories play.

Design and application of a data-independent precursor and product ion repository.

PubMed

Thalassinos, Konstantinos; Vissers, Johannes P C; Tenzer, Stefan; Levin, Yishai; Thompson, J Will; Daniel, David; Mann, Darrin; DeLong, Mark R; Moseley, M Arthur; America, Antoine H; Ottens, Andrew K; Cavey, Greg S; Efstathiou, Georgios; Scrivens, James H; Langridge, James I; Geromanos, Scott J

2012-10-01

The functional design and application of a data-independent LC-MS precursor and product ion repository for protein identification, quantification, and validation is conceptually described. The ion repository was constructed from the sequence search results of a broad range of discovery experiments investigating various tissue types of two closely related mammalian species. The relative high degree of similarity in protein complement, ion detection, and peptide and protein identification allows for the analysis of normalized precursor and product ion intensity values, as well as standardized retention times, creating a multidimensional/orthogonal queryable, qualitative, and quantitative space. Peptide ion map selection for identification and quantification is primarily based on replication and limited variation. The information is stored in a relational database and is used to create peptide- and protein-specific fragment ion maps that can be queried in a targeted fashion against the raw or time aligned ion detections. These queries can be conducted either individually or as groups, where the latter affords pathway and molecular machinery analysis of the protein complement. The presented results also suggest that peptide ionization and fragmentation efficiencies are highly conserved between experiments and practically independent of the analyzed biological sample when using similar instrumentation. Moreover, the data illustrate only minor variation in ionization efficiency with amino acid sequence substitutions occurring between species. Finally, the data and the presented results illustrate how LC-MS performance metrics can be extracted and utilized to ensure optimal performance of the employed analytical workflows.

10 CFR 960.3-3 - Consultation.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 4 2014-01-01 2014-01-01 false Consultation. 960.3-3 Section 960.3-3 Energy DEPARTMENT OF ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-3 Consultation. The DOE shall provide to designated officials of the affected...

10 CFR 960.3-3 - Consultation.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 4 2012-01-01 2012-01-01 false Consultation. 960.3-3 Section 960.3-3 Energy DEPARTMENT OF ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-3 Consultation. The DOE shall provide to designated officials of the affected...

10 CFR 960.3-3 - Consultation.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 4 2011-01-01 2011-01-01 false Consultation. 960.3-3 Section 960.3-3 Energy DEPARTMENT OF ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-3 Consultation. The DOE shall provide to designated officials of the affected...

10 CFR 960.3-3 - Consultation.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 4 2013-01-01 2013-01-01 false Consultation. 960.3-3 Section 960.3-3 Energy DEPARTMENT OF ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-3 Consultation. The DOE shall provide to designated officials of the affected...

Influence of climate on landscape characteristics in safety assessments of repositories for radioactive wastes.

PubMed

Becker, J K; Lindborg, T; Thorne, M C

2014-12-01

In safety assessments of repositories for radioactive wastes, large spatial and temporal scales have to be considered when developing an approach to risk calculations. A wide range of different types of information may be required. Local to the site of interest, temperature and precipitation data may be used to determine the erosional regime (which may also be conditioned by the vegetation characteristics adopted, based both on climatic and other considerations). However, geomorphological changes may be governed by regional rather than local considerations, e.g. alteration of river base levels, river capture and drainage network reorganisation, or the progression of an ice sheet or valley glacier across the site. The regional climate is in turn governed by the global climate. In this work, a commentary is presented on the types of climate models that can be used to develop projections of climate change for use in post-closure radiological impact assessments of geological repositories for radioactive wastes. These models include both Atmosphere-Ocean General Circulation Models and Earth Models of Intermediate Complexity. The relevant outputs available from these models are identified and consideration is given to how these outputs may be used to inform projections of landscape development. Issues of spatial and temporal downscaling of climate model outputs to meet the requirements of local-scale landscape development modelling are also addressed. An example is given of how climate change and landscape development influence the radiological impact of radionuclides potentially released from the deep geological disposal facility for spent nuclear fuel that SKB (the Swedish Nuclear Fuel and Waste Management Company) proposes to construct at Forsmark, Sweden. Copyright © 2014 Elsevier Ltd. All rights reserved.

Development of an 8000 bps voice codec for AvSat

NASA Technical Reports Server (NTRS)

Clark, Joseph F.

1988-01-01

Air-mobile speech communication applications share robustness and noise immunity requirements with other mobile applications. The quality requirements are stringent, especially in the cockpit where air safety is involved. Based on these considerations, a decision was made to test an intermediate data rate such as 8.0 and 9.6 kb/s as proven technologies. A number of vocoders and codec technologies were investigated at rates ranging from 2.4 kb/s up to and including 9.6 kb/s. The proven vocoders operating at 2.4 and 4.8 kb/s lacked the noise immunity or the robustness to operate reliably in a cabin noise environment. One very attractive alternative approach was Spectrally Encoded Residual Excited LPC (SE-RELP) which is used in a multi-rate voice processor (MRP) developed at the Naval Research Lab (NRL). The MRP uses SE-RELP at rates of 9.6 and 16 kb/s. The 9.6 kb/s rate can be lowered to 8.0 kb/s without loss of information by modifying the frame. An 8.0 kb/s vocoder was developed using SE-RELP as a demonstrator and testbed. This demonstrator is implemented in real time using two Compaq 2 portable computers, each equipped with an ARIEL DSP016 Data Acquisition Processor.

Packaging Strategies for Criticality Safety for "Other" DOE Fuels in a Repository

DOE Office of Scientific and Technical Information (OSTI.GOV)

Larry L Taylor

2004-06-01

Since 1998, there has been an ongoing effort to gain acceptance of U.S. Department of Energy (DOE)-owned spent nuclear fuel (SNF) in the national repository. To accomplish this goal, the fuel matrix was used as a discriminating feature to segregate fuels into nine distinct groups. From each of those groups, a characteristic fuel was selected and analyzed for criticality safety based on a proposed packaging strategy. This report identifies and quantifies the important criticality parameters for the canisterized fuels within each criticality group to: (1) demonstrate how the “other” fuels in the group are bounded by the baseline calculations ormore » (2) allow identification of individual type fuels that might require special analysis and packaging.« less

Radioactive waste isolation in salt: special advisory report on the status of the Office of Nuclear Waste Isolation's plans for repository performance assessment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ditmars, J.D.; Walbridge, E.W.; Rote, D.M.

1983-10-01

Repository performance assessment is analysis that identifies events and processes that might affect a repository system for isolation of radioactive waste, examines their effects on barriers to waste migration, and estimates the probabilities of their occurrence and their consequences. In 1983 Battelle Memorial Institute's Office of Nuclear Waste Isolation (ONWI) prepared two plans - one for performance assessment for a waste repository in salt and one for verification and validation of performance assessment technology. At the request of the US Department of Energy's Salt Repository Project Office (SRPO), Argonne National Laboratory reviewed those plans and prepared this report to advisemore » SRPO of specific areas where ONWI's plans for performance assessment might be improved. This report presents a framework for repository performance assessment that clearly identifies the relationships among the disposal problems, the processes underlying the problems, the tools for assessment (computer codes), and the data. In particular, the relationships among important processes and 26 model codes available to ONWI are indicated. A common suggestion for computer code verification and validation is the need for specific and unambiguous documentation of the results of performance assessment activities. A major portion of this report consists of status summaries of 27 model codes indicated as potentially useful by ONWI. The code summaries focus on three main areas: (1) the code's purpose, capabilities, and limitations; (2) status of the elements of documentation and review essential for code verification and validation; and (3) proposed application of the code for performance assessment of salt repository systems. 15 references, 6 figures, 4 tables.« less

Analysis of model output and science data in the Virtual Model Repository (VMR).

NASA Astrophysics Data System (ADS)

De Zeeuw, D.; Ridley, A. J.

2014-12-01

Big scientific data not only includes large repositories of data from scientific platforms like satelites and ground observation, but also the vast output of numerical models. The Virtual Model Repository (VMR) provides scientific analysis and visualization tools for a many numerical models of the Earth-Sun system. Individual runs can be analyzed in the VMR and compared to relevant data through relevant metadata, but larger collections of runs can also now be studied and statistics generated on the accuracy and tendancies of model output. The vast model repository at the CCMC with over 1000 simulations of the Earth's magnetosphere was used to look at overall trends in accuracy when compared to satelites such as GOES, Geotail, and Cluster. Methodology for this analysis as well as case studies will be presented.

Compliance with minimum information guidelines in public metabolomics repositories

PubMed Central

Spicer, Rachel A.; Salek, Reza; Steinbeck, Christoph

2017-01-01

The Metabolomics Standards Initiative (MSI) guidelines were first published in 2007. These guidelines provided reporting standards for all stages of metabolomics analysis: experimental design, biological context, chemical analysis and data processing. Since 2012, a series of public metabolomics databases and repositories, which accept the deposition of metabolomic datasets, have arisen. In this study, the compliance of 399 public data sets, from four major metabolomics data repositories, to the biological context MSI reporting standards was evaluated. None of the reporting standards were complied with in every publicly available study, although adherence rates varied greatly, from 0 to 97%. The plant minimum reporting standards were the most complied with and the microbial and in vitro were the least. Our results indicate the need for reassessment and revision of the existing MSI reporting standards. PMID:28949328

Compliance with minimum information guidelines in public metabolomics repositories.

PubMed

Spicer, Rachel A; Salek, Reza; Steinbeck, Christoph

2017-09-26

The Metabolomics Standards Initiative (MSI) guidelines were first published in 2007. These guidelines provided reporting standards for all stages of metabolomics analysis: experimental design, biological context, chemical analysis and data processing. Since 2012, a series of public metabolomics databases and repositories, which accept the deposition of metabolomic datasets, have arisen. In this study, the compliance of 399 public data sets, from four major metabolomics data repositories, to the biological context MSI reporting standards was evaluated. None of the reporting standards were complied with in every publicly available study, although adherence rates varied greatly, from 0 to 97%. The plant minimum reporting standards were the most complied with and the microbial and in vitro were the least. Our results indicate the need for reassessment and revision of the existing MSI reporting standards.

Sharing individual participant data from clinical trials: an opinion survey regarding the establishment of a central repository.

PubMed

Tudur Smith, Catrin; Dwan, Kerry; Altman, Douglas G; Clarke, Mike; Riley, Richard; Williamson, Paula R

2014-01-01

Calls have been made for increased access to individual participant data (IPD) from clinical trials, to ensure that complete evidence is available. However, despite the obvious benefits, progress towards this is frustratingly slow. In the meantime, many systematic reviews have already collected IPD from clinical trials. We propose that a central repository for these IPD should be established to ensure that these datasets are safeguarded and made available for use by others, building on the strengths and advantages of the collaborative groups that have been brought together in developing the datasets. Evaluate the level of support, and identify major issues, for establishing a central repository of IPD. On-line survey with email reminders. 71 reviewers affiliated with the Cochrane Collaboration's IPD Meta-analysis Methods Group were invited to participate. 30 (42%) invitees responded: 28 (93%) had been involved in an IPD review and 24 (80%) had been involved in a randomised trial. 25 (83%) agreed that a central repository was a good idea and 25 (83%) agreed that they would provide their IPD for central storage. Several benefits of a central repository were noted: safeguarding and standardisation of data, increased efficiency of IPD meta-analyses, knowledge advancement, and facilitating future clinical, and methodological research. The main concerns were gaining permission from trial data owners, uncertainty about the purpose of the repository, potential resource implications, and increased workload for IPD reviewers. Restricted access requiring approval, data security, anonymisation of data, and oversight committees were highlighted as issues under governance of the repository. There is support in this community of IPD reviewers, many of whom are also involved in clinical trials, for storing IPD in a central repository. Results from this survey are informing further work on developing a repository of IPD which is currently underway by our group.

Logistics Modeling of Emplacement Rate and Duration of Operations for Generic Geologic Repository Concepts

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kalinina, Elena Arkadievna; Hardin, Ernest

This study identified potential geologic repository concepts for disposal of spent nuclear fuel (SNF) and (2) evaluated the achievable repository waste emplacement rate and the time required to complete the disposal for these concepts. Total repository capacity is assumed to be approximately 140,000 MT of spent fuel. The results of this study provide an important input for the rough-order-of-magnitude (ROM) disposal cost analysis. The disposal concepts cover three major categories of host geologic media: crystalline or hard rock, salt, and argillaceous rock. Four waste package sizes are considered: 4PWR/9BWR; 12PWR/21BWR; 21PWR/44BWR, and dual purpose canisters (DPCs). The DPC concepts assumemore » that the existing canisters will be sealed into disposal overpacks for direct disposal. Each concept assumes one of the following emplacement power limits for either emplacement or repository closure: 1.7 kW; 2.2 kW; 5.5 kW; 10 kW; 11.5 kW, and 18 kW.« less

Building Connections, Collections, and Communities: Increasing the Visibility and Impact of Extension through Institutional Repositories

ERIC Educational Resources Information Center

Inefuku, Harrison W.; Franz, Nancy K.

2015-01-01

Over the past 20 years, university libraries have developed and manage institutional repositories--digital libraries that provide free, public access to the research, scholarship, and publications of their university's faculty, staff, and students. Although underused by Extension professionals, institutional repositories are powerful tools that…

A Framework for Integrating Oceanographic Data Repositories

NASA Astrophysics Data System (ADS)

Rozell, E.; Maffei, A. R.; Beaulieu, S. E.; Fox, P. A.

2010-12-01

Oceanographic research covers a broad range of science domains and requires a tremendous amount of cross-disciplinary collaboration. Advances in cyberinfrastructure are making it easier to share data across disciplines through the use of web services and community vocabularies. Best practices in the design of web services and vocabularies to support interoperability amongst science data repositories are only starting to emerge. Strategic design decisions in these areas are crucial to the creation of end-user data and application integration tools. We present S2S, a novel framework for deploying customizable user interfaces to support the search and analysis of data from multiple repositories. Our research methods follow the Semantic Web methodology and technology development process developed by Fox et al. This methodology stresses the importance of close scientist-technologist interactions when developing scientific use cases, keeping the project well scoped and ensuring the result meets a real scientific need. The S2S framework motivates the development of standardized web services with well-described parameters, as well as the integration of existing web services and applications in the search and analysis of data. S2S also encourages the use and development of community vocabularies and ontologies to support federated search and reduce the amount of domain expertise required in the data discovery process. S2S utilizes the Web Ontology Language (OWL) to describe the components of the framework, including web service parameters, and OpenSearch as a standard description for web services, particularly search services for oceanographic data repositories. We have created search services for an oceanographic metadata database, a large set of quality-controlled ocean profile measurements, and a biogeographic search service. S2S provides an application programming interface (API) that can be used to generate custom user interfaces, supporting data and application

Using neural networks in software repositories

NASA Technical Reports Server (NTRS)

Eichmann, David (Editor); Srinivas, Kankanahalli; Boetticher, G.

1992-01-01

The first topic is an exploration of the use of neural network techniques to improve the effectiveness of retrieval in software repositories. The second topic relates to a series of experiments conducted to evaluate the feasibility of using adaptive neural networks as a means of deriving (or more specifically, learning) measures on software. Taken together, these two efforts illuminate a very promising mechanism supporting software infrastructures - one based upon a flexible and responsive technology.

Evolution of computational models in BioModels Database and the Physiome Model Repository.

PubMed

Scharm, Martin; Gebhardt, Tom; Touré, Vasundra; Bagnacani, Andrea; Salehzadeh-Yazdi, Ali; Wolkenhauer, Olaf; Waltemath, Dagmar

2018-04-12

A useful model is one that is being (re)used. The development of a successful model does not finish with its publication. During reuse, models are being modified, i.e. expanded, corrected, and refined. Even small changes in the encoding of a model can, however, significantly affect its interpretation. Our motivation for the present study is to identify changes in models and make them transparent and traceable. We analysed 13734 models from BioModels Database and the Physiome Model Repository. For each model, we studied the frequencies and types of updates between its first and latest release. To demonstrate the impact of changes, we explored the history of a Repressilator model in BioModels Database. We observed continuous updates in the majority of models. Surprisingly, even the early models are still being modified. We furthermore detected that many updates target annotations, which improves the information one can gain from models. To support the analysis of changes in model repositories we developed MoSt, an online tool for visualisations of changes in models. The scripts used to generate the data and figures for this study are available from GitHub https://github.com/binfalse/BiVeS-StatsGenerator and as a Docker image at https://hub.docker.com/r/binfalse/bives-statsgenerator/ . The website https://most.bio.informatik.uni-rostock.de/ provides interactive access to model versions and their evolutionary statistics. The reuse of models is still impeded by a lack of trust and documentation. A detailed and transparent documentation of all aspects of the model, including its provenance, will improve this situation. Knowledge about a model's provenance can avoid the repetition of mistakes that others already faced. More insights are gained into how the system evolves from initial findings to a profound understanding. We argue that it is the responsibility of the maintainers of model repositories to offer transparent model provenance to their users.

Long-term safety assessment of trench-type surface repository at Chernobyl, Ukraine - computer model and comparison with results from simplified models

DOE Office of Scientific and Technical Information (OSTI.GOV)

Haverkamp, B.; Krone, J.; Shybetskyi, I.

2013-07-01

The Radioactive Waste Disposal Facility (RWDF) Buryakovka was constructed in 1986 as part of the intervention measures after the accident at Chernobyl NPP (ChNPP). Today, the surface repository for solid low and intermediate level waste (LILW) is still being operated but its maximum capacity is nearly reached. Long-existing plans for increasing the capacity of the facility shall be implemented in the framework of the European Commission INSC Programme (Instrument for Nuclear Safety Co-operation). Within the first phase of this project, DBE Technology GmbH prepared a safety analysis report of the facility in its current state (SAR) and a preliminary safetymore » analysis report (PSAR) for a future extended facility based on the planned enlargement. In addition to a detailed mathematical model, also simplified models have been developed to verify results of the former one and enhance confidence in the results. Comparison of the results show that - depending on the boundary conditions - simplifications like modeling the multi trench repository as one generic trench might have very limited influence on the overall results compared to the general uncertainties associated with respective long-term calculations. In addition to their value in regard to verification of more complex models which is important to increase confidence in the overall results, such simplified models can also offer the possibility to carry out time consuming calculations like probabilistic calculations or detailed sensitivity analysis in an economic manner. (authors)« less

Knowledge based system verification and validation as related to automation of space station subsystems: Rationale for a knowledge based system lifecycle

NASA Technical Reports Server (NTRS)

Richardson, Keith; Wong, Carla

1988-01-01

The role of verification and validation (V and V) in software has been to support and strengthen the software lifecycle and to ensure that the resultant code meets the standards of the requirements documents. Knowledge Based System (KBS) V and V should serve the same role, but the KBS lifecycle is ill-defined. The rationale of a simple form of the KBS lifecycle is presented, including accommodation to certain critical KBS differences from software development.

Motivations of Faculty Self-Archiving in Institutional Repositories

ERIC Educational Resources Information Center

Kim, Jihyun

2011-01-01

Professors contribute to Institutional Repositories (IRs) to make their materials widely accessible in keeping with the benefits of Open Access. However, universities' commitment to IRs depends on building trust with faculty and solving copyright concerns. Digital preservation and copyright management in IRs should be strengthened to increase…

Chemistry of transuranium elements in salt-base repository

DOE Office of Scientific and Technical Information (OSTI.GOV)

Borkowski, Marian; Reed, Donald T; Lucchini, Jean - Francois

2010-12-02

The mobility and potential release of actinides into the accessible environment continues to be the key performance assessment concern of nuclear repositories. Actinide, in particular plutonium speciation under the wide range of conditions that can exist in the subsurface is complex and depends strongly on the coupled effects of redox conditions, inorganic/organic complexation, and the extent/nature of aggregation. Understanding the key factors that define the potential for actinide migration is, in this context, an essential and critical part of making and sustaining a licensing case for a nuclear repository. Herein we report on recent progress in a concurrent modeling andmore » experimental study to determine the speciation of plutonium, uranium and americium in high ionic strength Na-CI-Mg brines. This is being done as part of the ongomg recertification effort m the Waste Isolation Pilot Plant (WIPP). The oxidation-state specific solubility of actinides were established in brine as function of pC{sub H+}, brine composition and the presence and absence of organic chelating agents and carbonate. An oxidation-state invariant analog approach using Nd{sup 3+} and Th{sup 4+} was used for An{sup 3+} and An{sup 4+} respectively. These results show that organic ligands and hydrolysis are key factors for An(III) solubility, hydrolysis at pC{sub H+} above 8 is predominate for An(IV) and carbonates are the key factor for U(VI) solubility. The effect of high ionic strength and brine components measured in absence of carbonates leads to measurable increased in overall solubility over analogous low ionic strength groundwater. Less is known about the bioreduction of actinides by halo-tolerant microorganisms, but there is now evidence that bioreduction does occur and is analogous, in many ways, to what occurs with soil bacteria. Results of solubility studies that focus on Pitzer parameter corrections, new species (e.g. borate complexation), and the thermodynamic parameters for

Investigating the Thermal Limit of Clay Minerals for Applications in Nuclear Waste Repository Design

NASA Astrophysics Data System (ADS)

Matteo, E. N.; Miller, A. W.; Kruichak, J.; Mills, M.; Tellez, H.; Wang, Y.

2013-12-01

Clay minerals are likely candidates to aid in nuclear waste isolation due to their low permeability, favorable swelling properties, and high cation sorption capacities. Establishing the thermal limit for clay minerals in a nuclear waste repository is a potentially important component of repository design, as flexibility of the heat load within the repository can have a major impact on the selection of repository design. For example, the thermal limit plays a critical role in the time that waste packages would need to cool before being transferred to the repository. Understanding the chemical and physical changes that occur in clay minerals at various temperatures above the current thermal limit (of 100 °C) can enable decision-makers with information critical to evaluating the potential trade-offs of increasing the thermal limit within the repository. Most critical is gaining understanding of how varying thermal conditions in the repository will impact radionuclide sorption and transport in clay materials either as engineered barriers or as disposal media. A variety of clays (illite, mixed layer illite/smectite, montmorillonite, and palygorskite) were heated for a range of temperatures between 100-500 °C. These samples were characterized by a variety of methods, including nitrogen adsorption, x-ray diffraction, thermogravimetric analysis, barium chloride exchange for cation exchange capacity (CEC), and iodide sorption. The nitrogen porosimetry shows that for all the clays, thermally-induced changes in BET surface area are dominated by collapse/creation of the microporosity, i.e. pore diameters < 17 angstroms. Changes in micro porosity (relative to no heat treatment) are most significant for heat treatments 300 °C and above. Alterations are also seen in the chemical properties (CEC, XRD, iodide sorption) of clays, and like pore size distribution changes, are most significant above 300 °C. Overall, the results imply that changes seen in pores size distribution

A web-based repository of surgical simulator projects.

PubMed

Leskovský, Peter; Harders, Matthias; Székely, Gábor

2006-01-01

The use of computer-based surgical simulators for training of prospective surgeons has been a topic of research for more than a decade. As a result, a large number of academic projects have been carried out, and a growing number of commercial products are available on the market. Keeping track of all these endeavors for established groups as well as for newly started projects can be quite arduous. Gathering information on existing methods, already traveled research paths, and problems encountered is a time consuming task. To alleviate this situation, we have established a modifiable online repository of existing projects. It contains detailed information about a large number of simulator projects gathered from web pages, papers and personal communication. The database is modifiable (with password protected sections) and also allows for a simple statistical analysis of the collected data. For further information, the surgical repository web page can be found at www.virtualsurgery.vision.ee.ethz.ch.

HepSim: A repository with predictions for high-energy physics experiments

DOE PAGES

Chekanov, S. V.

2015-02-03

A file repository for calculations of cross sections and kinematic distributions using Monte Carlo generators for high-energy collisions is discussed. The repository is used to facilitate effective preservation and archiving of data from theoretical calculations and for comparisons with experimental data. The HepSim data library is publicly accessible and includes a number of Monte Carlo event samples with Standard Model predictions for current and future experiments. The HepSim project includes a software package to automate the process of downloading and viewing online Monte Carlo event samples. Data streaming over a network for end-user analysis is discussed.

75 FR 26788 - Public Land Order No. 7742; Withdrawal of Public Land for the Manning Canyon Tailings Repository; UT

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-12

... 79765] Public Land Order No. 7742; Withdrawal of Public Land for the Manning Canyon Tailings Repository... period of 5 years to protect the integrity of the Manning Canyon Tailings Repository and surrounding... Repository. The Bureau of Land Management intends to evaluate the need for a lengthier withdrawal through the...

Damage-plasticity model of the host rock in a nuclear waste repository

DOE Office of Scientific and Technical Information (OSTI.GOV)

Koudelka, Tomáš; Kruis, Jaroslav, E-mail: kruis@fsv.cvut.cz

The paper describes damage-plasticity model for the modelling of the host rock environment of a nuclear waste repository. Radioactive Waste Repository Authority in Czech Republic assumes the repository to be in a granite rock mass which exhibit anisotropic behaviour where the strength in tension is lower than in compression. In order to describe this phenomenon, the damage-plasticity model is formulated with the help of the Drucker-Prager yield criterion which can be set to capture the compression behaviour while the tensile stress states is described with the help of scalar isotropic damage model. The concept of damage-plasticity model was implemented inmore » the SIFEL finite element code and consequently, the code was used for the simulation of the Äspö Pillar Stability Experiment (APSE) which was performed in order to determine yielding strength under various conditions in similar granite rocks as in Czech Republic. The results from the performed analysis are presented and discussed in the paper.« less

Characterization of Noise Signatures of Involuntary Head Motion in the Autism Brain Imaging Data Exchange Repository

PubMed Central

Caballero, Carla; Mistry, Sejal; Vero, Joe; Torres, Elizabeth B

2018-01-01

The variability inherently present in biophysical data is partly contributed by disparate sampling resolutions across instrumentations. This poses a potential problem for statistical inference using pooled data in open access repositories. Such repositories combine data collected from multiple research sites using variable sampling resolutions. One example is the Autism Brain Imaging Data Exchange repository containing thousands of imaging and demographic records from participants in the spectrum of autism and age-matched neurotypical controls. Further, statistical analyses of groups from different diagnoses and demographics may be challenging, owing to the disparate number of participants across different clinical subgroups. In this paper, we examine the noise signatures of head motion data extracted from resting state fMRI data harnessed under different sampling resolutions. We characterize the quality of the noise in the variability of the raw linear and angular speeds for different clinical phenotypes in relation to age-matched controls. Further, we use bootstrapping methods to ensure compatible group sizes for statistical comparison and report the ranges of physical involuntary head excursions of these groups. We conclude that different sampling rates do affect the quality of noise in the variability of head motion data and, consequently, the type of random process appropriate to characterize the time series data. Further, given a qualitative range of noise, from pink to brown noise, it is possible to characterize different clinical subtypes and distinguish them in relation to ranges of neurotypical controls. These results may be of relevance to the pre-processing stages of the pipeline of analyses of resting state fMRI data, whereby head motion enters the criteria to clean imaging data from motion artifacts. PMID:29556179

Audit of a Scientific Data Center for Certification as a Trustworthy Digital Repository: A Case Study

NASA Astrophysics Data System (ADS)

Downs, R. R.; Chen, R. S.

2011-12-01

Services that preserve and enable future access to scientific data are necessary to ensure that the data that are being collected today will be available for use by future generations of scientists. Many data centers, archives, and other digital repositories are working to improve their ability to serve as long-term stewards of scientific data. Trust in sustainable data management and preservation capabilities of digital repositories can influence decisions to use these services to deposit or obtain scientific data. Building on the Open Archival Information System (OAIS) Reference Model developed by the Consultative Committee for Space Data Systems (CCSDS) and adopted by the International Organization for Standardization as ISO 14721:2003, new standards are being developed to improve long-term data management processes and documentation. The Draft Information Standard ISO/DIS 16363, "Space data and information transfer systems - Audit and certification of trustworthy digital repositories" offers the potential to evaluate digital repositories objectively in terms of their trustworthiness as long-term stewards of digital resources. In conjunction with this, the CCSDS and ISO are developing another draft standard for the auditing and certification process, ISO/DIS 16919, "Space data and information transfer systems - Requirements for bodies providing audit and certification of candidate trustworthy digital repositories". Six test audits were conducted of scientific data centers and archives in Europe and the United States to test the use of these draft standards and identify potential improvements for the standards and for the participating digital repositories. We present a case study of the test audit conducted on the NASA Socioeconomic Data and Applications Center (SEDAC) and describe the preparation, the audit process, recommendations received, and next steps to obtain certification as a trustworthy digital repository, after approval of the ISO/DIS standards.

Automating RPM Creation from a Source Code Repository

DTIC Science & Technology

2012-02-01

apps/usr --with- libpq=/apps/ postgres make rm -rf $RPM_BUILD_ROOT umask 0077 mkdir -p $RPM_BUILD_ROOT/usr/local/bin mkdir -p $RPM_BUILD_ROOT...from a source code repository. %pre %prep %setup %build ./autogen.sh ; ./configure --with-db=/apps/db --with-libpq=/apps/ postgres make

Natural geochemical analogues of the near field of high-level nuclear waste repositories

DOE Office of Scientific and Technical Information (OSTI.GOV)

Apps, J.A.

1995-09-01

United States practice has been to design high-level nuclear waste (HLW) geological repositories with waste densities sufficiently high that repository temperatures surrounding the waste will exceed 100{degrees}C and could reach 250{degrees}C. Basalt and devitrified vitroclastic tuff are among the host rocks considered for waste emplacement. Near-field repository thermal behavior and chemical alteration in such rocks is expected to be similar to that observed in many geothermal systems. Therefore, the predictive modeling required for performance assessment studies of the near field could be validated and calibrated using geothermal systems as natural analogues. Examples are given which demonstrate the need for refinementmore » of the thermodynamic databases used in geochemical modeling of near-field natural analogues and the extent to which present models can predict conditions in geothermal fields.« less

10 CFR 960.3-2-2 - Nomination of sites as suitable for characterization.

Code of Federal Regulations, 2010 CFR

2010-01-01

... OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-2-2 Nomination of... of each repository site. For the second repository, at least three of the sites shall not have been nominated previously. Any site nominated as suitable for characterization for the first repository, but not...

Thermodynamic Properties of Magnesium Chloride Hydroxide Hydrate (Mg3Cl(OH)5:4H2O, Phase 5), and Its importance to Nuclear Waste Isolation in Geological Repositories in Salt Formations

NASA Astrophysics Data System (ADS)

Xiong, Y.; Deng, H.; Nemer, M. B.; Johnsen, S.

2009-12-01

MgO (bulk, pure MgO corresponding to the mineral periclase) is the only engineered barrier certified by the Environmental Protection Agency for emplacement in the Waste Isolation Pilot Plant (WIPP) in the US, and an Mg(OH)2-based engineered barrier (bulk, pure Mg(OH)2 corresponding to brucite) is to be employed in the Asse repository in Germany. Both the WIPP and the Asse are located in salt formations. The WIPP is a U.S. Department of Energy geological repository being used for the permanent disposal of defense-related transuranic waste (TRU waste). The repository is 655 m below the surface, and is situated in the Salado Formation, a Permian salt bed mainly composed of halite, and of lesser amounts of polyhalite, anhydrite, gypsum, magnesite, clays and quartz. The WIPP Generic Weep Brine (GWB), a Na-Mg-Cl dominated brine, is associated with the Salado Formation. The previous vendor for MgO for the WIPP was Premier Chemicals and the current vendor is Martin Marietta Materials. Experimental studies of both Premier MgO and Martin Marietta MgO with the GWB at SNL indicate the formation of magnesium chloride hydroxide hydrate, Mg3Cl(OH)5:4H2O, termed as phase 5. However, this important phase is lacking in the existing thermodynamic database. In this study, the solubility constant of phase 5 is determined from a series of solubility experiments in MgCl2-NaCl solutions. The solubility constant at 25 oC for the following reaction, Mg3Cl(OH)5:4H2O + 5H+ = 3Mg2+ + 9H2O(l) + Cl- is recommended as 43.21±0.33 (2σ) based on the Specific Interaction Theory (SIT) model for extrapolation to infinite dilution. The log K obtained via the Pitzer equations is identical to the above value within the quoted uncertainty. The Gibbs free energy and enthalpy of formation for phase 5 at 25 oC are derived as -3384±2 (2σ) kJ mol-1 and -3896±6 (2σ) kJ mol-1, respectively. The standard entropy and heat capacity of phase 5 at 25 oC are estimated as 393±20 J mol-1 K-1 and 374±19 J mol-1 K

The Efficacy of Institutional Repositories: Reflections on the Development of a Personalised Collection on UPSpace

ERIC Educational Resources Information Center

Olivier, Elsabe

2007-01-01

There is much speculation that the development of institutional repositories will impact on or even change the traditional scholarly communication process. The purpose of this conversation is to introduce the reader to the use of and response to institutional repositories which were initiated by the Open Access Initiative. The concept of…

The Royal Society of Chemistry and the delivery of chemistry data repositories for the community.

PubMed

Williams, Antony; Tkachenko, Valery

2014-10-01

Since 2009 the Royal Society of Chemistry (RSC) has been delivering access to chemistry data and cheminformatics tools via the ChemSpider database and has garnered a significant community following in terms of usage and contribution to the platform. ChemSpider has focused only on those chemical entities that can be represented as molecular connection tables or, to be more specific, the ability to generate an InChI from the input structure. As a structure centric hub ChemSpider is built around the molecular structure with other data and links being associated with this structure. As a result the platform has been limited in terms of the types of data that can be managed, and the flexibility of its searches, and it is constrained by the data model. New technologies and approaches, specifically taking into account a shift from relational to NoSQL databases, and the growing importance of the semantic web, has motivated RSC to rearchitect and create a more generic data repository utilizing these new technologies. This article will provide an overview of our activities in delivering data sharing platforms for the chemistry community including the development of the new data repository expanding into more extensive domains of chemistry data.

The Royal Society of Chemistry and the delivery of chemistry data repositories for the community

NASA Astrophysics Data System (ADS)

Williams, Antony; Tkachenko, Valery

2014-10-01

Since 2009 the Royal Society of Chemistry (RSC) has been delivering access to chemistry data and cheminformatics tools via the ChemSpider database and has garnered a significant community following in terms of usage and contribution to the platform. ChemSpider has focused only on those chemical entities that can be represented as molecular connection tables or, to be more specific, the ability to generate an InChI from the input structure. As a structure centric hub ChemSpider is built around the molecular structure with other data and links being associated with this structure. As a result the platform has been limited in terms of the types of data that can be managed, and the flexibility of its searches, and it is constrained by the data model. New technologies and approaches, specifically taking into account a shift from relational to NoSQL databases, and the growing importance of the semantic web, has motivated RSC to rearchitect and create a more generic data repository utilizing these new technologies. This article will provide an overview of our activities in delivering data sharing platforms for the chemistry community including the development of the new data repository expanding into more extensive domains of chemistry data.

10 CFR 51.67 - Environmental information concerning geologic repositories.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 2 2013-01-01 2013-01-01 false Environmental information concerning geologic repositories. 51.67 Section 51.67 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) ENVIRONMENTAL PROTECTION REGULATIONS FOR DOMESTIC LICENSING AND RELATED REGULATORY FUNCTIONS National Environmental Policy Act...

Connecting the pieces: Using ORCIDs to improve research impact and repositories.

PubMed

Baessa, Mohamed; Lery, Thibaut; Grenz, Daryl; Vijayakumar, J K

2015-01-01

Quantitative data are crucial in the assessment of research impact in the academic world. However, as a young university created in 2009, King Abdullah University of Science and Technology (KAUST) needs to aggregate bibliometrics from researchers coming from diverse origins, not necessarily with the proper affiliations. In this context, the University has launched an institutional repository in September 2012 with the objectives of creating a home for the intellectual outputs of KAUST researchers. Later, the university adopted the first mandated institutional open access policy in the Arab region, effective June 31, 2014. Several projects were then initiated in order to accurately identify the research being done by KAUST authors and bring it into the repository in accordance with the open access policy. Integration with ORCID has been a key element in this process and the best way to ensure data quality for researcher's scientific contributions. It included the systematic inclusion and creation, if necessary, of ORCID identifiers in the existing repository system, an institutional membership in ORCID, and the creation of dedicated integration tools. In addition and in cooperation with the Office of Research Evaluation, the Library worked at implementing a Current Research Information System (CRIS) as a standardized common resource to monitor KAUST research outputs. We will present our findings about the CRIS implementation, the ORCID API, the repository statistics as well as our approach in conducting the assessment of research impact in terms of usage by the global research community.

Indian Institutional Repositories: A Study of User's Perspective

ERIC Educational Resources Information Center

Sawant, Sarika

2012-01-01

Purpose: The present study aims to investigate the experience, contribution and opinions of users of respective institutional repositories (IRs) developed in India. Design/methodology/approach: The survey method was used. The data collection tool was a web questionnaire, which was created with the help of software provided by surveymonkey.com…

Linking User Identities Across the DataONE Federation of Data Repositories

NASA Astrophysics Data System (ADS)

Jones, M. B.; Mecum, B.; Leinfelder, B.; Jones, C. S.; Walker, L.

2016-12-01

DataONE provides services for identifying, authenticating, and authorizing researchers to access and contribute data to repositories within the DataONE federation. In the earth sciences, thousands of institutional and disciplinary repositories have created their own user identity and authentication systems with their own user directory based on a database or web content management systems. Thus, researchers have many identities that are neither linked nor interoperable, making it difficult to reference the identity of these users across systems. Key user information is hidden, and only a non-disambiguated name is often available. From a sample of 160,000 data sets within DataONE, a super-majority of references to the data creators lack even an email address. In an attempt to disambiguate these people via the GeoLink project, we conservatively estimate they represent at least 57,000 unique identities, but without a clear user identifier, there could be as many as 223,000. Interoperability among repositories is critical to improving the scope of scientific synthesis and capabilities for research collaboration. While many have focused on the convenience of Single Sign-On (SSO), we have found that sharing user identifiers is far more useful for interoperability. With an unambiguous user identity in incoming metadata, DataONE has built user-profiles that present that user's data across repositories, that link users and their organizational affiliations, and that allow users to work collaboratively in private groups that span repository systems. DataONE's user identity solution leverages existing systems such as InCommon, CILogon, Google, and ORCID to not further proliferate user identities. DataONE provides a core service allowing users to link their multiple identities so that authenticating with one identity (e.g., ORCID) can authorize access to data protected via another identity (e.g., InCommon). Currently, DataONE is using ORCID identities to link and identify

Phase formation and UV luminescence of Gd3+ doped perovskite-type YScO3

NASA Astrophysics Data System (ADS)

Shimizu, Yuhei; Ueda, Kazushige

2016-10-01

Synthesis of pure and Gd3+doped perovskite-type YScO3 was attempted by a polymerized complex (PC) method and solid state reaction (SSR) method. Crystalline phases and UV luminescence of samples were examined with varying heating temperatures. The perovskite-type single phase was not simply formed in the SSR method, as reported in some literatures, and two cubic C-type phases of starting oxide materials remained forming slightly mixed solid solutions. UV luminescence of Gd3+ doped samples increased with an increase in heating temperatures and volume of the perovskite-type phase. In contrast, a non-crystalline precursor was crystallized to a single C-type phase at 800 °C in the PC method forming a completely mixed solid solution. Then, the phase of perovskite-type YScO3 formed at 1200 °C and its single phase was obtained at 1400 °C. It was revealed that high homogeneousness of cations was essential to generate the single perovskite-phase of YScO3. Because Gd3+ ions were also dissolved into the single C-type phase in Gd3+ doped samples, intense UV luminescence was observed above 800 °C in both C-type phase and perovskite-type phase.

OntoCR: A CEN/ISO-13606 clinical repository based on ontologies.

PubMed

Lozano-Rubí, Raimundo; Muñoz Carrero, Adolfo; Serrano Balazote, Pablo; Pastor, Xavier

2016-04-01

To design a new semantically interoperable clinical repository, based on ontologies, conforming to CEN/ISO 13606 standard. The approach followed is to extend OntoCRF, a framework for the development of clinical repositories based on ontologies. The meta-model of OntoCRF has been extended by incorporating an OWL model integrating CEN/ISO 13606, ISO 21090 and SNOMED CT structure. This approach has demonstrated a complete evaluation cycle involving the creation of the meta-model in OWL format, the creation of a simple test application, and the communication of standardized extracts to another organization. Using a CEN/ISO 13606 based system, an indefinite number of archetypes can be merged (and reused) to build new applications. Our approach, based on the use of ontologies, maintains data storage independent of content specification. With this approach, relational technology can be used for storage, maintaining extensibility capabilities. The present work demonstrates that it is possible to build a native CEN/ISO 13606 repository for the storage of clinical data. We have demonstrated semantic interoperability of clinical information using CEN/ISO 13606 extracts. Copyright © 2016 Elsevier Inc. All rights reserved.

Automated Cancer Registry Notifications: Validation of a Medical Text Analytics System for Identifying Patients with Cancer from a State-Wide Pathology Repository

PubMed Central

Nguyen, Anthony N; Moore, Julie; O'Dwyer, John; Philpot, Shoni

2016-01-01

The paper assesses the utility of Medtex on automating Cancer Registry notifications from narrative histology and cytology reports from the Queensland state-wide pathology information system. A corpus of 45.3 million pathology HL7 messages (including 119,581 histology and cytology reports) from a Queensland pathology repository for the year of 2009 was analysed by Medtex for cancer notification. Reports analysed by Medtex were consolidated at a patient level and compared against patients with notifiable cancers from the Queensland Oncology Repository (QOR). A stratified random sample of 1,000 patients was manually reviewed by a cancer clinical coder to analyse agreements and discrepancies. Sensitivity of 96.5% (95% confidence interval: 94.5-97.8%), specificity of 96.5% (95.3-97.4%) and positive predictive value of 83.7% (79.6-86.8%) were achieved for identifying cancer notifiable patients. Medtex achieved high sensitivity and specificity across the breadth of cancers, report types, pathology laboratories and pathologists throughout the State of Queensland. The high sensitivity also resulted in the identification of cancer patients that were not found in the QOR. High sensitivity was at the expense of positive predictive value; however, these cases may be considered as lower priority to Cancer Registries as they can be quickly reviewed. Error analysis revealed that system errors tended to be tumour stream dependent. Medtex is proving to be a promising medical text analytic system. High value cancer information can be generated through intelligent data classification and extraction on large volumes of unstructured pathology reports. PMID:28269893

Automated Cancer Registry Notifications: Validation of a Medical Text Analytics System for Identifying Patients with Cancer from a State-Wide Pathology Repository.

PubMed

Nguyen, Anthony N; Moore, Julie; O'Dwyer, John; Philpot, Shoni

2016-01-01

The paper assesses the utility of Medtex on automating Cancer Registry notifications from narrative histology and cytology reports from the Queensland state-wide pathology information system. A corpus of 45.3 million pathology HL7 messages (including 119,581 histology and cytology reports) from a Queensland pathology repository for the year of 2009 was analysed by Medtex for cancer notification. Reports analysed by Medtex were consolidated at a patient level and compared against patients with notifiable cancers from the Queensland Oncology Repository (QOR). A stratified random sample of 1,000 patients was manually reviewed by a cancer clinical coder to analyse agreements and discrepancies. Sensitivity of 96.5% (95% confidence interval: 94.5-97.8%), specificity of 96.5% (95.3-97.4%) and positive predictive value of 83.7% (79.6-86.8%) were achieved for identifying cancer notifiable patients. Medtex achieved high sensitivity and specificity across the breadth of cancers, report types, pathology laboratories and pathologists throughout the State of Queensland. The high sensitivity also resulted in the identification of cancer patients that were not found in the QOR. High sensitivity was at the expense of positive predictive value; however, these cases may be considered as lower priority to Cancer Registries as they can be quickly reviewed. Error analysis revealed that system errors tended to be tumour stream dependent. Medtex is proving to be a promising medical text analytic system. High value cancer information can be generated through intelligent data classification and extraction on large volumes of unstructured pathology reports.

Attitudes to the Rights and Rewards for Author Contributions to Repositories for Teaching and Learning

ERIC Educational Resources Information Center

Bates, Melanie; Loddington, Steve; Manuel, Sue; Oppenheim, Charles

2007-01-01

In the United Kingdom over the past few years there has been a dramatic growth of national and regional repositories to collect and disseminate resources related to teaching and learning. Most notable of these are the Joint Information Systems Committee's Online Repository for [Learning and Teaching] Materials as well as the Higher Education…

Evaluation on radiation protection aspect and radiological risk at Mukim Belanja repository

DOE Office of Scientific and Technical Information (OSTI.GOV)

Azmi, Siti Nur Aisyah, E-mail: nuclear.aisyahazmi@gmail.com; Kenoh, Hamiza; Majid, Amran Ab.

2016-01-22

Asian Rare Earth (ARE) is a locally incorporated company that operated a mineral processing operation to extract rare earth element. ARE has received much attention from the public since the beginning of their operation until the work of decommissioning and decontamination of the plant. Due to the existence of Naturally Occurring Radioactive Material (NORM) in the residue, the decommissioning and disposal was done by the company in collaboration with the Perak State Government and the Atomic Energy Licensing Board (AELB). The main objective of this study is to review the level of compliance of the existing Radiation Protection Regulations enforcedmore » by AELB particularly in the achievement of allowed exposure dose limit. The next objective was to study the impact of the construction of the Mukim Belanja Repository to workers and public. This study was conducted by analyzing documents that were issued and conducting the area monitoring using a Geiger Muller detector (GM) and Sodium Iodide (NaI(Tl)) survey meters. The measurements were made at 5 cm and 1 m from the ground surface at 27 measurement stations. The external doses measured were within the background levels of the surrounding area. The annual effective dose using the highest reading at 5 cm and 1 m from ground surface by GM detector was calculated to be 1.36 mSv/year and 1.21 mSv/year respectively. Whereas the annual effective dose using the highest reading at 5 cm and 1 m from ground surface by using NaI(Tl) detector was calculated to be 3.31 mSv/year and 2.83 mSv/year respectively. The calculated cancer risks from the study showed that the risk is small compared with the risks derived from natural radiation based on global annual radiation dose to humans. This study therefore indicated that the repository is able to constrain the dose exposure from the disposed NORM waste. The study also revealed that the construction of the repository has complied with all the rules and regulations

Coupled THMC models for bentonite in clay repository for nuclear waste

NASA Astrophysics Data System (ADS)

Zheng, L.; Rutqvist, J.; Birkholzer, J. T.; Li, Y.; Anguiano, H. H.

2015-12-01

Illitization, the transformation of smectite to illite, could compromise some beneficiary features of an engineered barrier system (EBS) that is composed primarily of bentonite and clay host rock. It is a major determining factor to establish the maximum design temperature of the repositories because it is believed that illitization could be greatly enhanced at temperatures higher than 100 oC and thus significantly lower the sorption and swelling capacity of bentonite and clay rock. However, existing experimental and modeling studies on the occurrence of illitization and related performance impacts are not conclusive, in part because the relevant couplings between the thermal, hydrological, chemical, and mechanical (THMC) processes have not been fully represented in the models. Here we present fully coupled THMC simulations of a generic nuclear waste repository in a clay formation with bentonite-backfilled EBS. Two scenarios were simulated for comparison: a case in which the temperature in the bentonite near the waste canister can reach about 200 oC and a case in which the temperature in the bentonite near the waste canister peaks at about 100 oC. The model simulations demonstrate that illitization is in general more significant at higher temperatures. We also compared the chemical changes and the resulting swelling stress change for two types of bentonite: Kunigel-VI and FEBEX bentonite. Higher temperatures also lead to much higher stress in the near field, caused by thermal pressurization and vapor pressure buildup in the EBS bentonite and clay host rock. Chemical changes lead to a reduction in swelling stress, which is more pronounced for Kunigel-VI bentonite than for FEBEX bentonite.

10 CFR Appendix II to Part 960 - NRC and EPA Requirements for Preclosure Repository Performance

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 4 2012-01-01 2012-01-01 false NRC and EPA Requirements for Preclosure Repository Performance II Appendix II to Part 960 Energy DEPARTMENT OF ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Pt. 960, App. II Appendix II to Part 960—NRC and...

10 CFR Appendix II to Part 960 - NRC and EPA Requirements for Preclosure Repository Performance

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 4 2011-01-01 2011-01-01 false NRC and EPA Requirements for Preclosure Repository Performance II Appendix II to Part 960 Energy DEPARTMENT OF ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Pt. 960, App. II Appendix II to Part 960—NRC and...

10 CFR Appendix II to Part 960 - NRC and EPA Requirements for Preclosure Repository Performance

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 4 2013-01-01 2013-01-01 false NRC and EPA Requirements for Preclosure Repository Performance II Appendix II to Part 960 Energy DEPARTMENT OF ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Pt. 960, App. II Appendix II to Part 960—NRC and...

10 CFR Appendix I to Part 960 - NRC and EPA Requirements for Postclosure Repository Performance

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 4 2013-01-01 2013-01-01 false NRC and EPA Requirements for Postclosure Repository Performance I Appendix I to Part 960 Energy DEPARTMENT OF ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Pt. 960, App. I Appendix I to Part 960—NRC and...

10 CFR Appendix II to Part 960 - NRC and EPA Requirements for Preclosure Repository Performance

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 4 2014-01-01 2014-01-01 false NRC and EPA Requirements for Preclosure Repository Performance II Appendix II to Part 960 Energy DEPARTMENT OF ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Pt. 960, App. II Appendix II to Part 960—NRC and...

14 CFR 415.3 - Types of launch licenses.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 4 2011-01-01 2011-01-01 false Types of launch licenses. 415.3 Section 415.3 Aeronautics and Space COMMERCIAL SPACE TRANSPORTATION, FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION LICENSING LAUNCH LICENSE General § 415.3 Types of launch licenses. (a) Launch...

14 CFR 415.3 - Types of launch licenses.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Types of launch licenses. 415.3 Section 415.3 Aeronautics and Space COMMERCIAL SPACE TRANSPORTATION, FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION LICENSING LAUNCH LICENSE General § 415.3 Types of launch licenses. (a) Launch...

The World Sugarcane and Related Grasses Collection at USDA/ARS Genebank Repository in Miami, Florida, USA

USDA-ARS?s Scientific Manuscript database

In early 1980’s the USDA-ARS established the National Plant Germplasm System (NPGS) a network of gene banks to preserve genetic resources of importance to National and International agriculture. The National Clonal Germplasm Repository (NCGR) in Miami, Florida is one of these repositories. This repo...

Geochemical Results of Lysimeter Sampling at the Manning Canyon Repository in the Mercur Mining District, Utah

USGS Publications Warehouse

Earle, John; Choate, LaDonna

2010-01-01

This report presents chemical characteristics of transient unsaturated-zone water collected by lysimeter from the Manning Canyon repository site in Utah. Data collected by U.S. Geological Survey and U.S. Department of the Interior, Bureau of Land Management scientists under an intragovernmental order comprise the existing body of hydrochemical information on unsaturated-zone conditions at the site and represent the first effort to characterize the chemistry of the soil pore water surrounding the repository. Analyzed samples showed elevated levels of arsenic, barium, chromium, and strontium, which are typical of acidic mine drainage. The range of major-ion concentrations generally showed expected soil values. Although subsequent sampling is necessary to determine long-term effects of the repository, current results provide initial data concerning reactive processes of precipitation on the mine tailings and waste rock stored at the site and provide information on the effectiveness of reclamation operations at the Manning Canyon repository.

DNASU plasmid and PSI:Biology-Materials repositories: resources to accelerate biological research

PubMed Central

Seiler, Catherine Y.; Park, Jin G.; Sharma, Amit; Hunter, Preston; Surapaneni, Padmini; Sedillo, Casey; Field, James; Algar, Rhys; Price, Andrea; Steel, Jason; Throop, Andrea; Fiacco, Michael; LaBaer, Joshua

2014-01-01

The mission of the DNASU Plasmid Repository is to accelerate research by providing high-quality, annotated plasmid samples and online plasmid resources to the research community through the curated DNASU database, website and repository (http://dnasu.asu.edu or http://dnasu.org). The collection includes plasmids from grant-funded, high-throughput cloning projects performed in our laboratory, plasmids from external researchers, and large collections from consortia such as the ORFeome Collaboration and the NIGMS-funded Protein Structure Initiative: Biology (PSI:Biology). Through DNASU, researchers can search for and access detailed information about each plasmid such as the full length gene insert sequence, vector information, associated publications, and links to external resources that provide additional protein annotations and experimental protocols. Plasmids can be requested directly through the DNASU website. DNASU and the PSI:Biology-Materials Repositories were previously described in the 2010 NAR Database Issue (Cormier, C.Y., Mohr, S.E., Zuo, D., Hu, Y., Rolfs, A., Kramer, J., Taycher, E., Kelley, F., Fiacco, M., Turnbull, G. et al. (2010) Protein Structure Initiative Material Repository: an open shared public resource of structural genomics plasmids for the biological community. Nucleic Acids Res., 38, D743–D749.). In this update we will describe the plasmid collection and highlight the new features in the website redesign, including new browse/search options, plasmid annotations and a dynamic vector mapping feature that was developed in collaboration with LabGenius. Overall, these plasmid resources continue to enable research with the goal of elucidating the role of proteins in both normal biological processes and disease. PMID:24225319

ERM Ideas and Innovations: Digital Repository Management as ERM

ERIC Educational Resources Information Center

Pinkas, María M.; Lin, Na

2014-01-01

This article describes the application of electronic resources management (ERM) to digital repository management at the Health Sciences and Human Services Library at the University of Maryland, Baltimore. The authors discuss electronic resources management techniques, through the application of "Techniques for Electronic Management,"…

10 CFR 51.67 - Environmental information concerning geologic repositories.

Code of Federal Regulations, 2011 CFR

2011-01-01

... if it makes a substantial change in its proposed action that is relevant to environmental concerns or... 10 Energy 2 2011-01-01 2011-01-01 false Environmental information concerning geologic repositories. 51.67 Section 51.67 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) ENVIRONMENTAL PROTECTION...

Metadata Repository for Improved Data Sharing and Reuse Based on HL7 FHIR.

PubMed

Ulrich, Hannes; Kock, Ann-Kristin; Duhm-Harbeck, Petra; Habermann, Jens K; Ingenerf, Josef

2016-01-01

Unreconciled data structures and formats are a common obstacle to the urgently required sharing and reuse of data within healthcare and medical research. Within the North German Tumor Bank of Colorectal Cancer, clinical and sample data, based on a harmonized data set, is collected and can be pooled by using a hospital-integrated Research Data Management System supporting biobank and study management. Adding further partners who are not using the core data set requires manual adaptations and mapping of data elements. Facing this manual intervention and focusing the reuse of heterogeneous healthcare instance data (value level) and data elements (metadata level), a metadata repository has been developed. The metadata repository is an ISO 11179-3 conformant server application built for annotating and mediating data elements. The implemented architecture includes the translation of metadata information about data elements into the FHIR standard using the FHIR Data Element resource with the ISO 11179 Data Element Extensions. The FHIR-based processing allows exchange of data elements with clinical and research IT systems as well as with other metadata systems. With increasingly annotated and harmonized data elements, data quality and integration can be improved for successfully enabling data analytics and decision support.

Planting Seeds for a Successful Institutional Repository: Role of the Archivist as Manager, Designer, and Policymaker

ERIC Educational Resources Information Center

Watterworth, Melissa

2009-01-01

Recent surveys indicate that many colleges and universities have reached a pivotal moment in assessing the function and future development of their institutional repositories. Other surveys convey that archivists are participating in the development and implementation of institutional repositories at a variety of levels and have contributed to the…

iT2DMS: a Standard-Based Diabetic Disease Data Repository and its Pilot Experiment on Diabetic Retinopathy Phenotyping and Examination Results Integration.

PubMed

Wu, Huiqun; Wei, Yufang; Shang, Yujuan; Shi, Wei; Wang, Lei; Li, Jingjing; Sang, Aimin; Shi, Lili; Jiang, Kui; Dong, Jiancheng

2018-06-06

Type 2 diabetes mellitus (T2DM) is a common chronic disease, and the fragment data collected through separated vendors makes continuous management of DM patients difficult. The lack of standard of fragment data from those diabetic patients also makes the further potential phenotyping based on the diabetic data difficult. Traditional T2DM data repository only supports data collection from T2DM patients, lack of phenotyping ability and relied on standalone database design, limiting the secondary usage of these valuable data. To solve these issues, we proposed a novel T2DM data repository framework, which was based on standards. This repository can integrate data from various sources. It would be used as a standardized record for further data transfer as well as integration. Phenotyping was conducted based on clinical guidelines with KNIME workflow. To evaluate the phenotyping performance of the proposed system, data was collected from local community by healthcare providers and was then tested using algorithms. The results indicated that the proposed system could detect DR cases with an average accuracy of about 82.8%. Furthermore, these results had the promising potential of addressing fragmented data. The proposed system has integrating and phenotyping abilities, which could be used for diabetes research in future studies.

Generation and validation of a universal perinatal database and biospecimen repository: PeriBank.

PubMed

Antony, K M; Hemarajata, P; Chen, J; Morris, J; Cook, C; Masalas, D; Gedminas, M; Brown, A; Versalovic, J; Aagaard, K

2016-11-01

There is a dearth of biospecimen repositories available to perinatal researchers. In order to address this need, here we describe the methodology used to establish such a resource. With the collaboration of MedSci.net, we generated an online perinatal database with 847 fields of clinical information. Simultaneously, we established a biospecimen repository of the same clinical participants. The demographic and clinical outcomes data are described for the first 10 000 participants enrolled. The demographic characteristics are consistent with the demographics of the delivery hospitals. Quality analysis of the biospecimens reveals variation in very few analytes. Furthermore, since the creation of PeriBank, we have demonstrated validity of the database and tissue integrity of the biospecimen repository. Here we establish that the creation of a universal perinatal database and biospecimen collection is not only possible, but allows for the performance of state-of-the-science translational perinatal research and is a potentially valuable resource to academic perinatal researchers.

Genetic conservation, characterization and utilization of wild relatives of fruit and nut crops at the USDA Germplasm Repository in Davis, California

USDA-ARS?s Scientific Manuscript database

The National Clonal Germplasm Repository (NCGR) in Davis is one among the nine repositories in the National Plant Germplasm System, USDA-ARS that is responsible for conservation of clonally propagated woody perennial subtropical and temperate fruit and nut crop germplasm. Currently the repository ho...

Albedo Neutron Dosimetry in a Deep Geological Disposal Repository for High-Level Nuclear Waste.

PubMed

Pang, Bo; Becker, Frank

2017-04-28

Albedo neutron dosemeter is the German official personal neutron dosemeter in mixed radiation fields where neutrons contribute to personal dose. In deep geological repositories for high-level nuclear waste, where neutrons can dominate the radiation field, it is of interest to investigate the performance of albedo neutron dosemeter in such facilities. In this study, the deep geological repository is represented by a shielding cask loaded with spent nuclear fuel placed inside a rock salt emplacement drift. Due to the backscattering of neutrons in the drift, issues concerning calibration of the dosemeter arise. Field-specific calibration of the albedo neutron dosemeter was hence performed with Monte Carlo simulations. In order to assess the applicability of the albedo neutron dosemeter in a deep geological repository over a long time scale, spent nuclear fuel with different ages of 50, 100 and 500 years were investigated. It was found out, that the neutron radiation field in a deep geological repository can be assigned to the application area 'N1' of the albedo neutron dosemeter, which is typical in reactors and accelerators with heavy shielding. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Open Science CBS Neuroimaging Repository: Sharing ultra-high-field MR images of the brain.

PubMed

Tardif, Christine Lucas; Schäfer, Andreas; Trampel, Robert; Villringer, Arno; Turner, Robert; Bazin, Pierre-Louis

2016-01-01

Magnetic resonance imaging at ultra high field opens the door to quantitative brain imaging at sub-millimeter isotropic resolutions. However, novel image processing tools to analyze these new rich datasets are lacking. In this article, we introduce the Open Science CBS Neuroimaging Repository: a unique repository of high-resolution and quantitative images acquired at 7 T. The motivation for this project is to increase interest for high-resolution and quantitative imaging and stimulate the development of image processing tools developed specifically for high-field data. Our growing repository currently includes datasets from MP2RAGE and multi-echo FLASH sequences from 28 and 20 healthy subjects respectively. These datasets represent the current state-of-the-art in in-vivo relaxometry at 7 T, and are now fully available to the entire neuroimaging community. Copyright © 2015 Elsevier Inc. All rights reserved.

Rolling Deck to Repository (R2R): Products and Services for the U.S. Research Fleet Community

NASA Astrophysics Data System (ADS)

Arko, R. A.; Carbotte, S. M.; Chandler, C. L.; Smith, S. R.; Stocks, K. I.

2016-02-01

The Rolling Deck to Repository (R2R) program is working to ensure open access to environmental sensor data routinely acquired by the U.S. academic research fleet. Currently 25 vessels deliver 7 TB/year of data to R2R from a suite of geophysical, oceanographic, meteorological, and navigational sensors on over 400 cruises worldwide. R2R ensures these data are preserved in trusted repositories, discoverable via standard protocols, and adequately documented for reuse. R2R has recently expanded to include the vessels Sikuliaq, operated by the University of Alaska; Falkor, operated by the Schmidt Ocean Institute; and Ronald H. Brown and Okeanos Explorer, operated by NOAA. R2R maintains a master catalog of U.S. research cruises, currently holding over 4,670 expeditions including vessel and cruise identifiers, start/end dates and ports, project titles and funding awards, science parties, dataset inventories with instrument types and file formats, data quality assessments, and links to related content at other repositories. Standard post-field cruise products are published including shiptrack navigation, near-real-time MET/TSG data, underway geophysical profiles, and CTD profiles. Software tools available to users include the R2R Event Logger and the R2R Nav Manager. A Digital Object Identifier (DOI) is published for each cruise, original field sensor dataset, standard post-field product, and document (e.g. cruise report) submitted by the science party. Scientists are linked to personal identifiers such as ORCIDs where available. Using standard identifiers such as DOIs and ORCIDs facilitates linking with journal publications and generation of citation metrics. R2R collaborates in the Ocean Data Interoperability Platform (ODIP) to strengthen links among regional and national data systems, populates U.S. cruises in the POGO global catalog, and is working toward membership in the DataONE alliance. It is a lead partner in the EarthCube GeoLink project, developing Semantic Web

Institutional Repositories: The Experience of Master's and Baccalaureate Institutions

ERIC Educational Resources Information Center

Markey, Karen; St. Jean, Beth; Soo, Young Rieh; Yakel, Elizabeth; Kim, Jihyun

2008-01-01

In 2006, MIRACLE Project investigators censused library directors at all U.S. academic institutions about their activities planning, pilot testing, and implementing the institutional repositories on their campuses. Out of 446 respondents, 289 (64.8 percent) were from master's and baccalaureate institutions (M&BIs) where few operational…

The fault monitoring and diagnosis knowledge-based system for space power systems: AMPERES, phase 1

NASA Technical Reports Server (NTRS)

Lee, S. C.

1989-01-01

The objective is to develop a real time fault monitoring and diagnosis knowledge-based system (KBS) for space power systems which can save costly operational manpower and can achieve more reliable space power system operation. The proposed KBS was developed using the Autonomously Managed Power System (AMPS) test facility currently installed at NASA Marshall Space Flight Center (MSFC), but the basic approach taken for this project could be applicable for other space power systems. The proposed KBS is entitled Autonomously Managed Power-System Extendible Real-time Expert System (AMPERES). In Phase 1 the emphasis was put on the design of the overall KBS, the identification of the basic research required, the initial performance of the research, and the development of a prototype KBS. In Phase 2, emphasis is put on the completion of the research initiated in Phase 1, and the enhancement of the prototype KBS developed in Phase 1. This enhancement is intended to achieve a working real time KBS incorporated with the NASA space power system test facilities. Three major research areas were identified and progress was made in each area. These areas are real time data acquisition and its supporting data structure; sensor value validations; development of inference scheme for effective fault monitoring and diagnosis, and its supporting knowledge representation scheme.

Establishment of Peripheral Nerve Injury Data Repository to Monitor and Support Population Health Decisions

DTIC Science & Technology

2017-07-01

AWARD NUMBER: W81XWH-16-0-DM167033 TITLE: Establishment of Peripheral Nerve Injury Data Repository to Monitor and Support Population Health...Injury Data Repository to Monitor and Support Population Health Decisions 5a. CONTRACT NUMBER 5b. GRANT NUMBER W81XWH-16-0-DM167033 5c. PROGRAM...patient enrollment. Collected data will be utilized to 1) describe the outcomes of various PNI and 2) suggest outcomes that support population health

Personalized reminiscence therapy M-health application for patients living with dementia: Innovating using open source code repository.

PubMed

Zhang, Melvyn W B; Ho, Roger C M

2017-01-01

Dementia is known to be an illness which brings forth marked disability amongst the elderly individuals. At times, patients living with dementia do also experience non-cognitive symptoms, and these symptoms include that of hallucinations, delusional beliefs as well as emotional liability, sexualized behaviours and aggression. According to the National Institute of Clinical Excellence (NICE) guidelines, non-pharmacological techniques are typically the first-line option prior to the consideration of adjuvant pharmacological options. Reminiscence and music therapy are thus viable options. Lazar et al. [3] previously performed a systematic review with regards to the utilization of technology to delivery reminiscence based therapy to individuals who are living with dementia and has highlighted that technology does have benefits in the delivery of reminiscence therapy. However, to date, there has been a paucity of M-health innovations in this area. In addition, most of the current innovations are not personalized for each of the person living with Dementia. Prior research has highlighted the utility for open source repository in bioinformatics study. The authors hoped to explain how they managed to tap upon and make use of open source repository in the development of a personalized M-health reminiscence therapy innovation for patients living with dementia. The availability of open source code repository has changed the way healthcare professionals and developers develop smartphone applications today. Conventionally, a long iterative process is needed in the development of native application, mainly because of the need for native programming and coding, especially so if the application needs to have interactive features or features that could be personalized. Such repository enables the rapid and cost effective development of application. Moreover, developers are also able to further innovate, as less time is spend in the iterative process.

Phase formation and UV luminescence of Gd{sup 3+} doped perovskite-type YScO{sub 3}

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shimizu, Yuhei; Ueda, Kazushige, E-mail: kueda@che.kyutech.ac.jp

Synthesis of pure and Gd{sup 3+}doped perovskite-type YScO{sub 3} was attempted by a polymerized complex (PC) method and solid state reaction (SSR) method. Crystalline phases and UV luminescence of samples were examined with varying heating temperatures. The perovskite-type single phase was not simply formed in the SSR method, as reported in some literatures, and two cubic C-type phases of starting oxide materials remained forming slightly mixed solid solutions. UV luminescence of Gd{sup 3+} doped samples increased with an increase in heating temperatures and volume of the perovskite-type phase. In contrast, a non-crystalline precursor was crystallized to a single C-type phasemore » at 800 °C in the PC method forming a completely mixed solid solution. Then, the phase of perovskite-type YScO{sub 3} formed at 1200 °C and its single phase was obtained at 1400 °C. It was revealed that high homogeneousness of cations was essential to generate the single perovskite-phase of YScO{sub 3}. Because Gd{sup 3+} ions were also dissolved into the single C-type phase in Gd{sup 3+} doped samples, intense UV luminescence was observed above 800 °C in both C-type phase and perovskite-type phase. - Graphical abstract: A pure perovskite-type YScO{sub 3} phase was successfully synthesized by a polymerized complex (PC) method. The perovskite-type YScO{sub 3} was generated through a solid solution of C-type (Y{sub 0.5}Sc{sub 0.5}){sub 2}O{sub 3} with drastic change of morphology. The PC method enabled a preparation of the single phase of the perovskite-type YScO{sub 3} at lower temperature and in shorter heating time. Gd{sup 3+} doped perovskite-type YScO{sub 3} was found to show a strong sharp UV emission at 314 nm. - Highlights: • Pure YScO{sub 3} phase was successfully synthesized by polymerized complex (PC) method. • Pure perovskite-type YScO{sub 3} phase was generated from pure C-type (Y{sub 0.5}Sc{sub 0.5}){sub 2}O{sub 3} one. • YScO{sub 3} was obtained at lower

Rolling Deck to Repository (R2R): Linking and Integrating Data for Oceanographic Research

NASA Astrophysics Data System (ADS)

Arko, R. A.; Chandler, C. L.; Clark, P. D.; Shepherd, A.; Moore, C.

2012-12-01

The Rolling Deck to Repository (R2R) program is developing infrastructure to ensure the underway sensor data from NSF-supported oceanographic research vessels are routinely and consistently documented, preserved in long-term archives, and disseminated to the science community. We have published the entire R2R Catalog as a Linked Data collection, making it easily accessible to encourage linking and integration with data at other repositories. We are developing the R2R Linked Data collection with specific goals in mind: 1.) We facilitate data access and reuse by providing the richest possible collection of resources to describe vessels, cruises, instruments, and datasets from the U.S. academic fleet, including data quality assessment results and clean trackline navigation. We are leveraging or adopting existing community-standard concepts and vocabularies, particularly concepts from the Biological and Chemical Oceanography Data Management Office (BCO-DMO) ontology and terms from the pan-European SeaDataNet vocabularies, and continually re-publish resources as new concepts and terms are mapped. 2.) We facilitate data citation through the entire data lifecycle from field acquisition to shoreside archiving to (ultimately) global syntheses and journal articles. We are implementing globally unique and persistent identifiers at the collection, dataset, and granule levels, and encoding these citable identifiers directly into the Linked Data resources. 3.) We facilitate linking and integration with other repositories that publish Linked Data collections for the U.S. academic fleet, such as BCO-DMO and the Index to Marine and Lacustrine Geological Samples (IMLGS). We are initially mapping datasets at the resource level, and plan to eventually implement rule-based mapping at the concept level. We work collaboratively with partner repositories to develop best practices for URI patterns and consensus on shared vocabularies. The R2R Linked Data collection is implemented as a

Sharing environmental models: An Approach using GitHub repositories and Web Processing Services

NASA Astrophysics Data System (ADS)

Stasch, Christoph; Nuest, Daniel; Pross, Benjamin

2016-04-01

accordingly. The admin tool of the 52°North WPS was extended to support automated retrieval and deployment of computational models from GitHub repositories. Once the R code is available in the GitHub repo, the contained process can be easily deployed and executed by simply defining the GitHub repository URL in the WPS admin tool. We illustrate the usage of the approach by sharing and running a model for land use system archetypes developed by the Helmholtz Centre for Environmental Research (UFZ, see Vaclavik et al.). The original R code was extended and published in the 52°North WPS using both, public and non-public datasets (Nüst et al., see also https://github.com/52North/glues-wps). Hosting the analysis in a Git repository now allows WPS administrators, client developers, and modelers to easily work together on new versions or completely new web processes using the powerful GitHub collaboration platform. References: Hinz, M. et. al. (2013): Spatial Statistics on the Geospatial Web. In: The 16th AGILE International Conference on Geographic Information Science, Short Papers. http://www.agile-online.org/Conference_Paper/CDs/agile_2013/Short_Papers/SP_S3.1_Hinz.pdf Nüst, D. et. al.: (2015): Open and reproducible global land use classification. In: EGU General Assembly Conference Abstracts . Vol. 17. European Geophysical Union, 2015, p. 9125, http://meetingorganizer.copernicus. org/EGU2015/EGU2015- 9125.pdf Vaclavik, T., et. al. (2013): Mapping global land system archetypes. Global Environmental Change 23(6): 1637-1647. Online available: October 9, 2013, DOI: 10.1016/j.gloenvcha.2013.09.004

75 FR 80897 - Swap Data Repositories

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-23

...The Commodity Futures Trading Commission (``CFTC'' or ``Commission'') is proposing rules to implement new statutory provisions introduced by Title VII of the Dodd-Frank Wall Street Reform and Consumer Protection Act (``Dodd-Frank Act''). Section 728 of the Dodd-Frank Act amends the Commodity Exchange Act (``CEA'' or the ``Act'') by adding new Section 21, which establishes registration requirements, statutory duties, core principles and certain compliance obligations for registered swap data repositories (``SDRs'') and directs the Commission to adopt rules governing persons that are registered, as such, under this Section.

10 CFR 960.3-3 - Consultation.

Code of Federal Regulations, 2010 CFR

2010-01-01

... ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY..., operation, closure, decommissioning, licensing, or regulation of a repository. Written responses to written... purpose of determining the suitability of such area for the development of a repository, the DOE shall...

Bridging the Gap: Need for a Data Repository to Support Vaccine Prioritization Efforts*

PubMed Central

Madhavan, Guruprasad; Phelps, Charles; Sangha, Kinpritma; Levin, Scott; Rappuoli, Rino

2015-01-01

As the mechanisms for discovery, development, and delivery of new vaccines become increasingly complex, strategic planning and priority setting have become ever more crucial. Traditional single value metrics such as disease burden or cost-effectiveness no longer suffice to rank vaccine candidates for development. The Institute of Medicine—in collaboration with the National Academy of Engineering—has developed a novel software system to support vaccine prioritization efforts. The Strategic Multi-Attribute Ranking Tool for Vaccines—SMART Vaccines—allows decision makers to specify their own value structure, selecting from among 28 pre-defined and up to 7 user-defined attributes relevant to the ranking of vaccine candidates. Widespread use of SMART Vaccines will require compilation of a comprehensive data repository for numerous relevant populations—including their demographics, disease burdens and associated treatment costs, as well as characterizing performance features of potential or existing vaccines that might be created, improved, or deployed. While the software contains preloaded data for a modest number of populations, a large gap exists between the existing data and a comprehensive data repository necessary to make full use of SMART Vaccines. While some of these data exist in disparate sources and forms, constructing a data repository will require much new coordination and focus. Finding strategies to bridge the gap to a comprehensive data repository remains the most important task in bringing SMART Vaccines to full fruition, and to support strategic vaccine prioritization efforts in general. PMID:26022565

Assessment of Self-Archiving in Institutional Repositories: Across Disciplines

ERIC Educational Resources Information Center

Xia, Jingfeng

2007-01-01

This research examined self-archiving practices by four disciplines in seven institutional repositories. By checking each individual item for its metadata and deposition status, the research found that a disciplinary culture is not obviously presented. Rather, self-archiving is regulated by a liaison system and a mandate policy.

Institutional Repositories in Universities in Nigeria: Desirability and Progress

ERIC Educational Resources Information Center

Oye, Peter Olorunlake; Oyeniyi, David Ajibola; Mahan, David Ezekiel

2017-01-01

The desire of academic institutions to link up to the virtual repository is a global phenomenon. Traditional scholarly publication through established journals characterized by peer review is being challenged by less formal net-based communication that links scholars essentially instantaneously. The contention is that universities need to preserve…

Current Status of The Romanian National Deep Geological Repository Program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Radu, M.; Nicolae, R.; Nicolae, D.

2008-07-01

Construction of a deep geological repository is a very demanding and costly task. By now, countries that have Candu reactors, have not processed the spent fuel passing to the interim storage as a preliminary step of final disposal within the nuclear fuel cycle back-end. Romania, in comparison to other nations, represents a rather small territory, with high population density, wherein the geological formation areas with radioactive waste storage potential are limited and restricted not only from the point of view of the selection criteria due to the rocks natural characteristics, but also from the point of view of their involvementmore » in social and economical activities. In the framework of the national R and D Programs, series of 'Map investigations' have been made regarding the selection and preliminary characterization of the host geological formation for the nation's spent fuel deep geological repository. The fact that Romania has many deposits of natural gas, oil, ore and geothermal water, and intensively utilizes soil and also is very forested, cause some of the apparent acceptable sites to be rejected in the subsequent analysis. Currently, according to the Law on the spent fuel and radioactive waste management, including disposal, The National Agency of Radioactive Waste is responsible and coordinates the national strategy in the field and, subsequently, further actions will be decided. The Romanian National Strategy, approved in 2004, projects the operation of a deep geological repository to begin in 2055. (authors)« less

Analysis of Academic Attitudes and Existing Processes to Inform the Design of Teaching and Learning Material Repositories: A User-Centred Approach

ERIC Educational Resources Information Center

King, Melanie; Loddington, Steve; Manuel, Sue; Oppenheim, Charles

2008-01-01

The last couple of years have brought a rise in the number of institutional repositories throughout the world and within UK Higher Education institutions, with the majority of these repositories being devoted to research output. Repositories containing teaching and learning material are less common and the workflows and business processes…

Determination of gross alpha and gross beta in soil around repository facility at Bukit Kledang, Perak, Malaysia

NASA Astrophysics Data System (ADS)

Adziz, Mohd Izwan Abdul; Siong, Khoo Kok

2018-04-01

Recently, the Long Term Storage Facility (LTSF) in Bukit Kledang, Perak, Malaysia, has been upgraded to repository facility upon the completion of decontamination and decommissioning (D&D) process. Thorium waste and contaminated material that may contain some minor amounts of thorium hydroxide were disposed in this facility. This study is conducted to determine the concentrations of gross alpha and gross beta radioactivities in soil samples collected around the repository facility. A total of 12 soil samples were collected consisting 10 samples from around the facility and 2 samples from selected residential area near the facility. In addition, the respective dose rates were measured 5 cm and 1 m above the ground by using survey meter with Geiger Muller (GM) detector and Sodium Iodide (NaI) detector. Soil samples were collected using hand auger and then were taken back to the laboratory for further analysis. Samples were cleaned, dried, pulverized and sieved prior to analysis. Gross alpha and gross beta activity measurements were carried out using gas flow proportional counter, Canberra Series 5 XLB - Automatic Low Background Alpha and Beta Counting System. The obtained results show that, the gross alpha and gross beta activity concentration ranged from 1.55 to 5.34 Bq/g with a mean value of 3.47 ± 0.09 Bq/g and 1.64 to 5.78 Bq/g with a mean value of 3.49 ± 0.09 Bq/g, respectively. These results can be used as an additional data to represent terrestrial radioactivity baseline data for Malaysia environment. This estimation will also serve as baseline for detection of any future related activities of contamination especially around the repository facility area.

The SeaView EarthCube project: Lessons Learned from Integrating Across Repositories

NASA Astrophysics Data System (ADS)

Diggs, S. C.; Stocks, K. I.; Arko, R. A.; Kinkade, D.; Shepherd, A.; Olson, C. J.; Pham, A.

2017-12-01

SeaView is an NSF-funded EarthCube Integrative Activity Project working with 5 existing data repositories* to provide oceanographers with highly integrated thematic data collections in user-requested formats. The project has three complementary goals: Supporting Scientists: SeaView targets scientists' need for easy access to data of interest that are ready to import into their preferred tool. Strengthening Repositories: By integrating data from multiple repositories for science use, SeaView is helping the ocean data repositories align their data and processes and make ocean data more accessible and easily integrated. Informing EarthCube (earthcube.org): SeaView's experience as an integration demonstration can inform the larger NSF EarthCube architecture and design effort. The challenges faced in this small-scale effort are informative to geosciences cyberinfrastructure more generally. Here we focus on the lessons learned that may inform other data facilities and integrative architecture projects. (The SeaView data collections will be presented at the Ocean Sciences 2018 meeting.) One example is the importance of shared semantics, with persistent identifiers, for key integration elements across the data sets (e.g. cruise, parameter, and project/program.) These must allow for revision through time and should have an agreed authority or process for resolving conflicts: aligning identifiers and correcting errors were time consuming and often required both deep domain knowledge and "back end" knowledge of the data facilities. Another example is the need for robust provenance, and tools that support automated or semi-automated data transform pipelines that capture provenance. Multiple copies and versions of data are now flowing into repositories, and onward to long-term archives such as NOAA NCEI and umbrella portals such as DataONE. Exact copies can be identified with hashes (for those that have the skills), but it can be painfully difficult to understand the processing

Do academic knowledge brokers exist? Using social network analysis to explore academic research-to-policy networks from six schools of public health in Kenya

PubMed Central

Jessani, Nasreen S; Boulay, Marc G; Bennett, Sara C

2016-01-01

The potential for academic research institutions to facilitate knowledge exchange and influence evidence-informed decision-making has been gaining ground. Schools of public health (SPHs) may play a key knowledge brokering role—serving as agencies of and for development. Understanding academic-policymaker networks can facilitate the enhancement of links between policymakers and academic faculty at SPHs, as well as assist in identifying academic knowledge brokers (KBs). Using a census approach, we administered a sociometric survey to academic faculty across six SPHs in Kenya to construct academic-policymaker networks. We identified academic KBs using social network analysis (SNA) in a two-step approach: First, we ranked individuals based on (1) number of policymakers in their network; (2) number of academic peers who report seeking them out for advice on knowledge translation and (3) their network position as ‘inter-group connectors’. Second, we triangulated the three scores and re-ranked individuals. Academic faculty scoring within the top decile across all three measures were classified as KBs. Results indicate that each SPH commands a variety of unique as well as overlapping relationships with national ministries in Kenya. Of 124 full-time faculty, we identified 7 KBs in 4 of the 6 SPHs. Those scoring high on the first measure were not necessarily the same individuals scoring high on the second. KBs were also situated in a wide range along the ‘connector/betweenness’ measure. We propose that a composite score rather than traditional ‘betweenness centrality’, provides an alternative means of identifying KBs within these networks. In conclusion, SNA is a valuable tool for identifying academic-policymaker networks in Kenya. More efforts to conduct similar network studies would permit SPH leadership to identify existing linkages between faculty and policymakers, shared linkages with other SPHs and gaps so as to contribute to evidence-informed health

[Characterization of air mycobiota in two repositories of the National Archives of the Republic of Cuba].

PubMed

Borrego Alonso, Sofía; Perdomo Amistad, Ivette

2014-01-01

The high relative humidity and temperatures in tropical countries create favorable conditions for development of fungi that are not only a risk to human health but they can also colonize documentary support. To study the concentration of the airborne fungi in two repositories of the National Archives of the Republic of Cuba, the mycobiota deposited on different photographic supports and maps preserved in these repositories, and to determine the taxonomic characterization of the fungi isolated. The air sampling was performed using a sedimentation method, and the supports (6 pictures and 7 maps) were analyzed using moistened sterile swabs. The Cladosporium genus was predominant, followed by Aspergillus and Penicillium genera. Filamentous fungi were isolated in all the photos and maps, and yeasts were only isolated from a photographic supports and a map. We identified several species of Aspergillus and Penicillium genera, but Aspergillus niger and Aspergillus flavus predominated. Candida and Rhodotorula were the yeast genera isolated. The fungal concentration of the air demonstrated that the environments were not contaminated. From the 26 species of filamentous fungi isolated only 5 were detected in the indoor air of the repositories and on one or more of the document supports analyzed (representing a 19.3%). This shows that there is a low ecological relationship between the fungi detected in the indoor air and those that were isolated from the supports studied. Copyright © 2012 Revista Iberoamericana de Micología. Published by Elsevier Espana. All rights reserved.

10 CFR 960.3-2-2-4 - The environmental assessment.

Code of Federal Regulations, 2012 CFR

2012-01-01

...; and an assessment of the regional and local impacts of locating a repository at the site. The draft... 10 Energy 4 2012-01-01 2012-01-01 false The environmental assessment. 960.3-2-2-4 Section 960.3-2... FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-2-2-4 The environmental assessment...

10 CFR 960.3-2-2-4 - The environmental assessment.

Code of Federal Regulations, 2014 CFR

2014-01-01

...; and an assessment of the regional and local impacts of locating a repository at the site. The draft... 10 Energy 4 2014-01-01 2014-01-01 false The environmental assessment. 960.3-2-2-4 Section 960.3-2... FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-2-2-4 The environmental assessment...

10 CFR 960.3-2-2-4 - The environmental assessment.

Code of Federal Regulations, 2013 CFR

2013-01-01

...; and an assessment of the regional and local impacts of locating a repository at the site. The draft... 10 Energy 4 2013-01-01 2013-01-01 false The environmental assessment. 960.3-2-2-4 Section 960.3-2... FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-2-2-4 The environmental assessment...

10 CFR 960.3-1-1 - Diversity of geohydrologic settings.

Code of Federal Regulations, 2010 CFR

2010-01-01

... SITES FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-1-1 Diversity of geohydrologic... development of repositories may be located. To the extent practicable, sites recommended as candidate sites...

Making the Most of What We Have Got: Enhancing the RADAR Repository to Support Research Planning

ERIC Educational Resources Information Center

Pike, Dawn; Siminson, Nicola Jane

2017-01-01

This article discusses how RADAR, the institutional repository (IR) at the Glasgow School of Art (GSA), has been modified to house an Annual Research Planning (ARP) template. A case study on the implementation of this research planning tool will outline the role that a repository and its staff can play in supporting individuals, enhancing…

Development and Implementation of a Learning Object Repository for French Teaching and Learning: Issues and Promises

ERIC Educational Resources Information Center

Caws, Catherine

2008-01-01

This paper discusses issues surrounding the development of a learning object repository (FLORE) for teaching and learning French at the postsecondary level. An evaluation based on qualitative and quantitative data was set up in order to better assess how second-language (L2) students in French perceived the integration of this new repository into…

Developing the Tools for Geologic Repository Monitoring - Andra's Monitoring R and D Program - 12045

DOE Office of Scientific and Technical Information (OSTI.GOV)

Buschaert, S.; Lesoille, S.; Bertrand, J.

2012-07-01

The French Safety Guide recommends that Andra develop a monitoring program to be implemented during repository construction and conducted until (and possibly after) closure, in order to confirm expected behavior and enhance knowledge of relevant processes. To achieve this, Andra has developed an overall monitoring strategy and identified specific technical objectives to inform disposal process management on evolutions relevant to both the long term safety and reversible, pre-closure management of the repository. Andra has launched an ambitious R and D program to ensure that reliable, durable, metrologically qualified and tested monitoring systems will be available at the time of repositorymore » construction in order to respond to monitoring objectives. After four years of a specific R and D program, first observations are described and recommendations are proposed. The results derived from 4 years of Andra's R and D program allow three main observations to be shared. First, while other industries also invest in monitoring equipment, their obvious emphasis will always be on their specific requirements and needs, thus often only providing a partial match with repository requirements. Examples can be found for all available sensors, which are generally not resistant to radiation. Second, the very close scrutiny anticipated for the geologic disposal process is likely to place an unprecedented emphasis on the quality of monitoring results. It therefore seems important to emphasize specific developments with an aim at providing metrologically qualified systems. Third, adapting existing technology to specific repository needs, and providing adequate proof of their worth, is a lengthy process. In conclusion, it therefore seems prudent to plan ahead and to invest wisely in the adequate development of those monitoring tools that will likely be needed in the repository to respond to the implementers' and regulators' requirements, including those agreed and developed to

The Geodetic Seamless Archive Centers Service Layer: A System Architecture for Federating Geodesy Data Repositories

NASA Astrophysics Data System (ADS)

McWhirter, J.; Boler, F. M.; Bock, Y.; Jamason, P.; Squibb, M. B.; Noll, C. E.; Blewitt, G.; Kreemer, C. W.

2010-12-01

Three geodesy Archive Centers, Scripps Orbit and Permanent Array Center (SOPAC), NASA's Crustal Dynamics Data Information System (CDDIS) and UNAVCO are engaged in a joint effort to define and develop a common Web Service Application Programming Interface (API) for accessing geodetic data holdings. This effort is funded by the NASA ROSES ACCESS Program to modernize the original GPS Seamless Archive Centers (GSAC) technology which was developed in the 1990s. A new web service interface, the GSAC-WS, is being developed to provide uniform and expanded mechanisms through which users can access our data repositories. In total, our respective archives hold tens of millions of files and contain a rich collection of site/station metadata. Though we serve similar user communities, we currently provide a range of different access methods, query services and metadata formats. This leads to a lack of consistency in the userís experience and a duplication of engineering efforts. The GSAC-WS API and its reference implementation in an underlying Java-based GSAC Service Layer (GSL) supports metadata and data queries into site/station oriented data archives. The general nature of this API makes it applicable to a broad range of data systems. The overall goals of this project include providing consistent and rich query interfaces for end users and client programs, the development of enabling technology to facilitate third party repositories in developing these web service capabilities and to enable the ability to perform data queries across a collection of federated GSAC-WS enabled repositories. A fundamental challenge faced in this project is to provide a common suite of query services across a heterogeneous collection of data yet enabling each repository to expose their specific metadata holdings. To address this challenge we are developing a "capabilities" based service where a repository can describe its specific query and metadata capabilities. Furthermore, the architecture of

Working paper : the ITS cost data repository at Mitretek Systems

DOT National Transportation Integrated Search

1998-11-30

Mitretek Systems has been tasked by the Intelligent Transportation Systems (ITS) Joint Program Office (JPO) to collect available information on ITS costs and maintain the information in a cost database, which serves as the ITS Cost Data Repository. T...

10 CFR 960.3-2-1 - Site screening for potentially acceptable sites.

Code of Federal Regulations, 2010 CFR

2010-01-01

... POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-2-1 Site screening for... first repository, the process shall begin with site-screening activities that consider large land masses... repositories, the Secretary shall first identify the State within which the site is located in a decision-basis...

Evolution in Metadata Quality: Common Metadata Repository's Role in NASA Curation Efforts

NASA Technical Reports Server (NTRS)

Gilman, Jason; Shum, Dana; Baynes, Katie

2016-01-01

Metadata Quality is one of the chief drivers of discovery and use of NASA EOSDIS (Earth Observing System Data and Information System) data. Issues with metadata such as lack of completeness, inconsistency, and use of legacy terms directly hinder data use. As the central metadata repository for NASA Earth Science data, the Common Metadata Repository (CMR) has a responsibility to its users to ensure the quality of CMR search results. This poster covers how we use humanizers, a technique for dealing with the symptoms of metadata issues, as well as our plans for future metadata validation enhancements. The CMR currently indexes 35K collections and 300M granules.

FAIRDOMHub: a repository and collaboration environment for sharing systems biology research.

PubMed

Wolstencroft, Katherine; Krebs, Olga; Snoep, Jacky L; Stanford, Natalie J; Bacall, Finn; Golebiewski, Martin; Kuzyakiv, Rostyk; Nguyen, Quyen; Owen, Stuart; Soiland-Reyes, Stian; Straszewski, Jakub; van Niekerk, David D; Williams, Alan R; Malmström, Lars; Rinn, Bernd; Müller, Wolfgang; Goble, Carole

2017-01-04

The FAIRDOMHub is a repository for publishing FAIR (Findable, Accessible, Interoperable and Reusable) Data, Operating procedures and Models (https://fairdomhub.org/) for the Systems Biology community. It is a web-accessible repository for storing and sharing systems biology research assets. It enables researchers to organize, share and publish data, models and protocols, interlink them in the context of the systems biology investigations that produced them, and to interrogate them via API interfaces. By using the FAIRDOMHub, researchers can achieve more effective exchange with geographically distributed collaborators during projects, ensure results are sustained and preserved and generate reproducible publications that adhere to the FAIR guiding principles of data stewardship. © The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

Preservation Health Check: Monitoring Threats to Digital Repository Content

ERIC Educational Resources Information Center

Kool, Wouter; van der Werf, Titia; Lavoie, Brian

2014-01-01

The Preservation Health Check (PHC) project, undertaken as a joint effort by Open Planets Foundation (OPF) and OCLC Research, aims to evaluate the usefulness of the preservation metadata created and maintained by operational repositories for assessing basic preservation properties. The PHC project seeks to develop an implementable logic to support…

Content Analysis of a Computer-Based Faculty Activity Repository

ERIC Educational Resources Information Center

Baker-Eveleth, Lori; Stone, Robert W.

2013-01-01

The research presents an analysis of faculty opinions regarding the introduction of a new computer-based faculty activity repository (FAR) in a university setting. The qualitative study employs content analysis to better understand the phenomenon underlying these faculty opinions and to augment the findings from a quantitative study. A web-based…

A Remote Knowledge Repository System for Teaching and Learning.

ERIC Educational Resources Information Center

Martins, Protasio D.; Maidantchik, Carmen; Lemos, Leandro T.; Manoel de Seixas, Jose

Changes in the global economy and the extensive use of the internet implied a conceptual redefinition of the working and social structure, and consequently an enhancement of educational systems that instruct engineers. This paper presents a repository of remote multimedia information such as formatted or non-formatted documents, hypertext pages,…

Proposed BioRepository platform solution for the ALS research community.

PubMed

Sherman, Alex; Bowser, Robert; Grasso, Daniela; Power, Breen; Milligan, Carol; Jaffa, Matthew; Cudkowicz, Merit

2011-01-01

ALS is a rare disorder whose cause and pathogenesis is largely unknown ( 1 ). There is a recognized need to develop biomarkers for ALS to better understand the disease, expedite diagnosis and to facilitate therapy development. Collaboration is essential to obtain a sufficient number of samples to allow statistically meaningful studies. The availability of high quality biological specimens for research purposes requires the development of standardized methods for collection, long-term storage, retrieval and distribution of specimens. The value of biological samples to scientists and clinicians correlates with the completeness and relevance of phenotypical and clinical information associated with the samples ( 2 , 3 ). While developing a secure Web-based system to manage an inventory of multi-site BioRepositories, algorithms were implemented to facilitate ad hoc parametric searches across heterogeneous data sources that contain data from clinical trials and research studies. A flexible schema for a barcode label was introduced to allow association of samples to these data. The ALSBank™ BioRepository platform solution for managing biological samples and associated data is currently deployed by the Northeast ALS Consortium (NEALS). The NEALS Consortium and the Massachusetts General Hospital (MGH) Neurology Clinical Trials Unit (NCTU) support a network of multiple BioBanks, thus allowing researchers to take advantage of a larger specimen collection than they might have at an individual institution. Standard operating procedures are utilized at all collection sites to promote common practices for biological sample integrity, quality control and associated clinical data. Utilizing this platform, we have created one of the largest virtual collections of ALS-related specimens available to investigators studying ALS.

10 CFR 960.3-2-2-2 - Selection of sites within geohydrologic settings.

Code of Federal Regulations, 2010 CFR

2010-01-01

... OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-2-2-2 Selection... nominated as suitable for characterization. For purposes of the second and subsequent repositories, due... suitable for the development of a repository under the qualifying condition of each guideline specified in...

Radiation induced corrosion of copper for spent nuclear fuel storage

NASA Astrophysics Data System (ADS)

Björkbacka, Åsa; Hosseinpour, Saman; Johnson, Magnus; Leygraf, Christofer; Jonsson, Mats

2013-11-01

The long term safety of repositories for radioactive waste is one of the main concerns for countries utilizing nuclear power. The integrity of engineered and natural barriers in such repositories must be carefully evaluated in order to minimize the release of radionuclides to the biosphere. One of the most developed concepts of long term storage of spent nuclear fuel is the Swedish KBS-3 method. According to this method, the spent fuel will be sealed inside copper canisters surrounded by bentonite clay and placed 500 m down in stable bedrock. Despite the importance of the process of radiation induced corrosion of copper, relatively few studies have been reported. In this work the effect of the total gamma dose on radiation induced corrosion of copper in anoxic pure water has been studied experimentally. Copper samples submerged in water were exposed to a series of total doses using three different dose rates. Unirradiated samples were used as reference samples throughout. The copper surfaces were examined qualitatively using IRAS and XPS and quantitatively using cathodic reduction. The concentration of copper in solution after irradiation was measured using ICP-AES. The influence of aqueous radiation chemistry on the corrosion process was evaluated based on numerical simulations. The experiments show that the dissolution as well as the oxide layer thickness increase upon radiation. Interestingly, the evaluation using numerical simulations indicates that aqueous radiation chemistry is not the only process driving the corrosion of copper in these systems.

10 CFR 960.3-2-2-5 - Formal site nomination.

Code of Federal Regulations, 2010 CFR

2010-01-01

... NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-2-2-5 Formal site nomination. After the final... determines suitable for site characterization for the selection of a repository site, and, in so doing, he...

10 CFR 960.3-2-2-4 - The environmental assessment.

Code of Federal Regulations, 2010 CFR

2010-01-01

... FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-2-2-4 The environmental assessment...; and an assessment of the regional and local impacts of locating a repository at the site. The draft...

10 CFR 960.3-1-4 - Evidence for siting decisions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-1-4 Evidence for siting decisions. The siting... recommendation of a candidate site for the development of a repository. Each of these decisions will be supported...

Implementation of an OAIS Repository Using Free, Open Source Software

NASA Astrophysics Data System (ADS)

Flathers, E.; Gessler, P. E.; Seamon, E.

2015-12-01

The Northwest Knowledge Network (NKN) is a regional data repository located at the University of Idaho that focuses on the collection, curation, and distribution of research data. To support our home institution and others in the region, we offer services to researchers at all stages of the data lifecycle—from grant application and data management planning to data distribution and archive. In this role, we recognize the need to work closely with other data management efforts at partner institutions and agencies, as well as with larger aggregation efforts such as our state geospatial data clearinghouses, data.gov, DataONE, and others. In the past, one of our challenges with monolithic, prepackaged data management solutions is that customization can be difficult to implement and maintain, especially as new versions of the software are released that are incompatible with our local codebase. Our solution is to break the monolith up into its constituent parts, which offers us several advantages. First, any customizations that we make are likely to fall into areas that can be accessed through Application Program Interfaces (API) that are likely to remain stable over time, so our code stays compatible. Second, as components become obsolete or insufficient to meet new demands that arise, we can replace the individual components with minimal effect on the rest of the infrastructure, causing less disruption to operations. Other advantages include increased system reliability, staggered rollout of new features, enhanced compatibility with legacy systems, reduced dependence on a single software company as a point of failure, and the separation of development into manageable tasks. In this presentation, we describe our application of the Service Oriented Architecture (SOA) design paradigm to assemble a data repository that conforms to the Open Archival Information System (OAIS) Reference Model primarily using a collection of free and open-source software. We detail the design

Role of natural analogs in performance assessment of nuclear waste repositories

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sagar, B.; Wittmeyer, G.W.

1995-09-01

Mathematical models of the flow of water and transport of radionuclides in porous media will be used to assess the ability of deep geologic repositories to safely contain nuclear waste. These models must, in some sense, be validated to ensure that they adequately describe the physical processes occurring within the repository and its geologic setting. Inasmuch as the spatial and temporal scales over which these models must be applied in performance assessment are very large, validation of these models against laboratory and small-scale field experiments may be considered inadequate. Natural analogs may provide validation data that are representative of physico-chemicalmore » processes that occur over spatial and temporal scales as large or larger than those relevant to repository design. The authors discuss the manner in which natural analog data may be used to increase confidence in performance assessment models and conclude that, while these data may be suitable for testing the basic laws governing flow and transport, there is insufficient control of boundary and initial conditions and forcing functions to permit quantitative validation of complex, spatially distributed flow and transport models. The authors also express their opinion that, for collecting adequate data from natural analogs, resources will have to be devoted to them that are much larger than are devoted to them at present.« less

Establishment and Maintenance of Primary Fibroblast Repositories for Rare Diseases-Friedreich's Ataxia Example.

PubMed

Li, Yanjie; Polak, Urszula; Clark, Amanda D; Bhalla, Angela D; Chen, Yu-Yun; Li, Jixue; Farmer, Jennifer; Seyer, Lauren; Lynch, David; Butler, Jill S; Napierala, Marek

2016-08-01

Friedreich's ataxia (FRDA) represents a rare neurodegenerative disease caused by expansion of GAA trinucleotide repeats in the first intron of the FXN gene. The number of GAA repeats in FRDA patients varies from approximately 60 to <1000 and is tightly correlated with age of onset and severity of the disease symptoms. The heterogeneity of Friedreich's ataxia stresses the need for a large cohort of patient samples to conduct studies addressing the mechanism of disease pathogenesis or evaluate novel therapeutic candidates. Herein, we report the establishment and characterization of an FRDA fibroblast repository, which currently includes 50 primary cell lines derived from FRDA patients and seven lines from mutation carriers. These cells are also a source for generating induced pluripotent stem cell (iPSC) lines by reprogramming, as well as disease-relevant neuronal, cardiac, and pancreatic cells that can then be differentiated from the iPSCs. All FRDA and carrier lines are derived using a standard operating procedure and characterized to confirm mutation status, as well as expression of FXN mRNA and protein. Consideration and significance of creating disease-focused cell line and tissue repositories, especially in the context of rare and heterogeneous disorders, are presented. Although the economic aspect of creating and maintaining such repositories is important, the benefits of easy access to a collection of well-characterized cell lines for the purpose of drug discovery or disease mechanism studies overshadow the associated costs. Importantly, all FRDA fibroblast cell lines collected in our repository are available to the scientific community.