Sample records for kenkyu kaihatsu kobe-shi

  1. Teachers Learning from Each Other in Japan through Jugyou Kenkyu.

    ERIC Educational Resources Information Center

    Arani, Mohammad Reza Sarkar

    Many school-based inservice teacher training programs are available to Japanese teachers, including observing classes in other schools, inviting parents to observe and provide feedback, and conducting collaborative research on the teaching-learning process (Jugyou Kenkyu). This article highlights Jugyou Kenkyu, which is based on three steps…

  2. The Kobe Earthquake: Telecommunications Survives at Kobe University.

    ERIC Educational Resources Information Center

    Garland, Virginia E.; Morimoto, Mayumi

    1996-01-01

    Describes the use of telecommunications in the aftermath of the Kobe earthquake. Topics include the use of e-mail for communication as well as for disaster relief efforts, use of the Internet and World Wide Web home pages, and the usefulness of portable computers with built-in modems for fax capabilities. (LRW)

  3. Contribution of Kobe University to the Regional Centre of Expertise (RCE) on Education for Sustainable Development (ESD) Hyogo-Kobe

    ERIC Educational Resources Information Center

    Itoh, Masayuki; Suemoto, Makoto; Matsuoka, Koji; Ito, Atsushi; Yui, Kiyomitsu; Matsuda, Tsuyoshi; Ishikawa, Masanobu

    2008-01-01

    Purpose: The purpose of this paper is to introduce the Regional Centre of Expertise (RCE) on education for sustainable development (ESD) Hyogo-Kobe, and the contribution of Kobe University as a model case. An attempt to develop and implement a new ESD programme in higher education is also reported. Design/methodology/approach: A brief description…

  4. The Long-Run Socio-Economic Consequences of a Large Disaster: The 1995 Earthquake in Kobe

    PubMed Central

    duPont IV, William; Noy, Ilan; Okuyama, Yoko; Sawada, Yasuyuki

    2015-01-01

    We quantify the ‘permanent’ socio-economic impacts of the Great Hanshin-Awaji (Kobe) earthquake in 1995 by employing a large-scale panel dataset of 1,719 cities, towns, and wards from Japan over three decades. In order to estimate the counterfactual—i.e., the Kobe economy without the earthquake—we use the synthetic control method. Three important empirical patterns emerge: First, the population size and especially the average income level in Kobe have been lower than the counterfactual level without the earthquake for over fifteen years, indicating a permanent negative effect of the earthquake. Such a negative impact can be found especially in the central areas which are closer to the epicenter. Second, the surrounding areas experienced some positive permanent impacts in spite of short-run negative effects of the earthquake. Much of this is associated with movement of people to East Kobe, and consequent movement of jobs to the metropolitan center of Osaka, that is located immediately to the East of Kobe. Third, the furthest areas in the vicinity of Kobe seem to have been insulated from the large direct and indirect impacts of the earthquake. PMID:26426998

  5. The Long-Run Socio-Economic Consequences of a Large Disaster: The 1995 Earthquake in Kobe.

    PubMed

    duPont, William; Noy, Ilan; Okuyama, Yoko; Sawada, Yasuyuki

    2015-01-01

    We quantify the 'permanent' socio-economic impacts of the Great Hanshin-Awaji (Kobe) earthquake in 1995 by employing a large-scale panel dataset of 1,719 cities, towns, and wards from Japan over three decades. In order to estimate the counterfactual--i.e., the Kobe economy without the earthquake--we use the synthetic control method. Three important empirical patterns emerge: First, the population size and especially the average income level in Kobe have been lower than the counterfactual level without the earthquake for over fifteen years, indicating a permanent negative effect of the earthquake. Such a negative impact can be found especially in the central areas which are closer to the epicenter. Second, the surrounding areas experienced some positive permanent impacts in spite of short-run negative effects of the earthquake. Much of this is associated with movement of people to East Kobe, and consequent movement of jobs to the metropolitan center of Osaka, that is located immediately to the East of Kobe. Third, the furthest areas in the vicinity of Kobe seem to have been insulated from the large direct and indirect impacts of the earthquake.

  6. International Comparison of Causative Bacteria and Antimicrobial Susceptibilities of Urinary Tract Infections between Kobe, Japan, and Surabaya, Indonesia.

    PubMed

    Kitagawa, Koichi; Shigemura, Katsumi; Yamamichi, Fukashi; Alimsardjono, Lindawati; Rahardjo, Dadik; Kuntaman, Kuntaman; Shirakawa, Toshiro; Fujisawa, Masato

    2018-01-23

    Variation by country in urinary tract infection (UTI)-causative bacteria is partly due to the differences in the use of antibiotics. We compared their frequencies and antibiotic susceptibilities in the treatment of patients with UTI from 2 cities, Kobe, Japan, and Surabaya, Indonesia. We retrospectively analyzed 1,804 urine samples collected from patients with UTI in 2014 (1,251 collected in 11 months at Kobe University Hospital in Kobe and 544 collected in 2 months at Dr. Soetomo Hospital in Surabaya). Surabaya data were divided into adult and pediatric patients because a substantial number of specimens from pediatric-patients had been collected. The results indicated that Escherichia coli was the most common uropathogen (24.1% in Kobe and 39.3% in Surabaya) and was significantly resistant to ampicillin and substantially to first- and third-generation cephalosporins in Surabaya adults but not in Kobe adults (p < 0.01). Enterococcus faecalis was often isolated in Kobe (14.0%), but not in Surabaya (5.3%). Klebsiella spp. were isolated at a higher rate in Surabaya pediatric patients (20.3%) than in Surabaya adults (13.6%) and Kobe adults (6.6%). The antibiotic susceptibilities of the isolates form Surabaya isolates tended to be lower than the ones from Kobe. Extended-spectrum β-lactamase-producing Gram-negative bacteria were detected at a significantly higher rate in Surabaya than in Kobe (p < 0.001). These results showed that the antimicrobial resistance patterns of UTI-causative bacteria are highly variable among 2 countries, and the continuous surveillance of trends in antibiotic resistance patterns of uropathogens is necessary for the future revision of antibiotic use.

  7. The Shi’a Crescent: A Misconception of Shi’a Alliance

    DTIC Science & Technology

    2014-12-01

    wear the hijab , set up illegal sharia courts, and imposed their own brutal penalties.”47 The country’s demography was tolerant toward a sectarian... A MISCONCEPTION OF SHI’A ALLIANCE by Rowaida Alamiri December 2014 Thesis Advisor: Anne Marie Baylouny Second Reader Mohammed Hafez...Master ’s Thesis 4. TITLE AND SUBTITLE 5. FUNDING NUMBERS THE SHI’ A CRESCENT: A MISCONCEPTION OF SHI’ A ALLIANCE 6. AUTHOR(S) Rowaida Alamiri 7

  8. On precursory ULF/ELF electromagnetic signatures for the Kobe earthquake on April 12, 2013

    NASA Astrophysics Data System (ADS)

    Schekotov, A.; Izutsu, J.; Hayakawa, M.

    2015-12-01

    After the 2011 Tohoku earthquake (EQ), there have been numerous aftershocks in the eastern and Pacific Ocean of Japan, but EQs are still rare in the western part of Japan. In this situation a relatively large (magnitude (M) ∼ 6) EQ happened on April 12 (UT), 2013 at a place close to the 1995 Kobe EQ (M ∼ 7), so we have tried to find whether there existed any electromagnetic precursors to this EQ. Two precursory signatures are detected: one is the depression of ULF (ultra-low-frequency, 0.01-0.02 Hz) geomagnetic variations on April 9, and the second is wideband ELF (extremely low frequency) electromagnetic radiation on April 11. These results for the 2013 Kobe EQ are compared with the corresponding results for the former 1995 Kobe EQ.

  9. [Research activities in Kobe-Indonesia Collaborative Research Centers].

    PubMed

    Utsumi, Takako; Hayashi, Yoshitake; Hotta, Hak

    2013-01-01

    Kobe-Indonesia Collaborative Research Center was established in Institute of Tropical Disease (ITD), Airlangga University, Surabaya, Indonesia in 2007 under the program of ''Founding Research Centers for Emerging and Reemerging Infectious Diseases'' supported by the Ministry of Education, Culture, Sports, Science and Technology, Japan, and then it has been under the Japan Initiative for Global Research Network on Infectious Diseases (J-GRID) since 2010. Japanese researchers have been stationed at ITD, conducting joint researches on influenza, viral hepatitis, dengue and infectious diarrhea. Also, another Japanese researcher has been stationed at Faculty of Medicine, University of Indonesia, Jakarta, carrying out joint researches on'' Identification of anti-hepatitis C virus (HCV) substances and development of HCV and dengue vaccines'' in collaboration with University of Indonesia and Airlangga University through the Science and Technology Research Partnership for Sustainable Development (SATREPS) supported by the Japan Science and Technology Agency (JST) and Japan International Cooperation Agency (JICA) since 2009. In this article, we briefly introduce the background history of Kobe University Research Center in Indonesia, and discuss the research themes and outcomes of J-GRID and SATREPS activities.

  10. The Shy Child in Physical Education.

    ERIC Educational Resources Information Center

    Connelly, Deidre

    1988-01-01

    This article describes ways in which physical education teachers may influence shy children in order to reduce their shy behavior by working closely with them to encourage class participation, motivating them to develop new skills, and offering positive reinforcement of pro-social behavior. Twelve steps are described. (JL)

  11. Learning from Japanese Approach to Teachers' Professional Development: Can "Jugyou Kenkyu" Work in Other Countries?

    ERIC Educational Resources Information Center

    Masami, Matoba; Reza, Sarkar Arani M.

    2005-01-01

    This paper tries to present a careful analysis of current trends and challenges to importing Japanese model of teachers' professional development. The objective is to examine what "we" can learn from Japanese approach to improving instruction, especially "Jugyou Kenkyu" (Lesson Study) as a collaborative research on the…

  12. Women stereotypes in Shi Zhecun's short stories.

    PubMed

    Rosenmeier, Christopher

    2010-01-01

    This article analyses the representation of women in two 1933 short story collections by Shi Zhecun: An Evening of Spring Rain and Exemplary Conduct of Virtuous Women. It discusses how the New Woman image was a site of contestation in Republican China, and argues that Shi Zhecun’s short stories contain four basic stereotypes: the enigmatic woman, the estranged wife, the prostitute, and the inhibited woman. Using these narratives of women and how they were perceived by men, Shi Zhecun deconstructed the New Woman image by subverting the various ways modernity was projected onto women.

  13. Stress transferred by the 1995 Mw = 6.9 Kobe, Japan, shock: Effect on aftershocks and future earthquake probabilities

    USGS Publications Warehouse

    Toda, S.; Stein, R.S.; Reasenberg, P.A.; Dieterich, J.H.; Yoshida, A.

    1998-01-01

    The Kobe earthquake struck at the edge of the densely populated Osaka-Kyoto corridor in southwest Japan. We investigate how the earthquake transferred stress to nearby faults, altering their proximity to failure and thus changing earthquake probabilities. We find that relative to the pre-Kobe seismicity, Kobe aftershocks were concentrated in regions of calculated Coulomb stress increase and less common in regions of stress decrease. We quantify this relationship by forming the spatial correlation between the seismicity rate change and the Coulomb stress change. The correlation is significant for stress changes greater than 0.2-1.0 bars (0.02-0.1 MPa), and the nonlinear dependence of seismicity rate change on stress change is compatible with a state- and rate-dependent formulation for earthquake occurrence. We extend this analysis to future mainshocks by resolving the stress changes on major faults within 100 km of Kobe and calculating the change in probability caused by these stress changes. Transient effects of the stress changes are incorporated by the state-dependent constitutive relation, which amplifies the permanent stress changes during the aftershock period. Earthquake probability framed in this manner is highly time-dependent, much more so than is assumed in current practice. Because the probabilities depend on several poorly known parameters of the major faults, we estimate uncertainties of the probabilities by Monte Carlo simulation. This enables us to include uncertainties on the elapsed time since the last earthquake, the repeat time and its variability, and the period of aftershock decay. We estimate that a calculated 3-bar (0.3-MPa) stress increase on the eastern section of the Arima-Takatsuki Tectonic Line (ATTL) near Kyoto causes fivefold increase in the 30-year probability of a subsequent large earthquake near Kyoto; a 2-bar (0.2-MPa) stress decrease on the western section of the ATTL results in a reduction in probability by a factor of 140 to

  14. Postseismic Deformation following the 1995 Kobe, Japan, Earthquake Detected by Space Geodesy

    NASA Astrophysics Data System (ADS)

    Hashimoto, Manabu; Ozawa, Taku; Nishimura, Takuya; Munekane, Hiroshi; Tobita, Mikio

    2017-04-01

    A Mw 6.8 earthquake hit the city of Kobe, southwest Japan, and its surrounding area on January 17, 1995, and claimed more than 6,400 fatalities. The source faults, trending in the NE-SW direction, are estimated beneath the foothill of the Rokko Mountains, which are located north of the city and the highest peak is 931 m high, but it has a dominant right lateral strike slip components. The Rokko Mountains may have been built by the motion of active faults, but the uplift during the 1995 earthquake may not be enough. Therefore there is a possibility that postseismic deformation contributes to the building of the Rokko Mountains. In order to study the postseismic deformation following the Kobe earthquake, we collected all available space geodetic data during about 20 years, including ERS-1/2, Envisat, JERS-1, ALOS/PALSAR and ALOS-2/PALSAR-2 images and continuous GPS data, and reanalyzed them. Especially, temporal continuous GPS observation made by the Geographical Survey Institute (present the Geospatial Information Authority), Japan in and around the Kobe area is important. We recalculated coordinates of these continuous GPS stations with recent PPP procedure using reanalyzed orbits and clocks of satellites. We made DInSAR and PSInSAR analyses of SAR images using ASTER-GDEM ver.2 or GSI DEM. Time series analysis of JERS-1 images revealed line-of-sight (LOS) decrease of the Rokko Mountains. PS-InSAR results of ALOS/PALSAR also revealed slight uplift north of the Rokko Mountains that uplifted by 20 cm coseismically. These observations suggest that the Rokko Mountains might have uplifted during the postseismic period. LOS increase in a wedge shaped region between two active faults east of the Rokko Mountains in the vicinity of the NE terminus of the source fault of the Kobe earthquake. The LOS increase is also confirmed by ERS-1/2, Envisat and ALOS/PALSAR images. These facts indicate that the subsidence between these two faults continued up to 2010. Continuous GPS

  15. Are shy adults really bolder online? It depends on the context.

    PubMed

    Brunet, Paul M; Schmidt, Louis A

    2008-12-01

    We examined whether individual differences in shyness and context influenced the amount of computer-mediated self-disclosure and use of affective language during an unfamiliar dyadic social interaction. Unfamiliar young adults were selected for high and low self-reported shyness and paired in mixed dyads (one shy and one nonshy). Each dyad was randomly assigned to either a live webcam or no webcam condition. Participants then engaged in a 20-minute online free chat over the Internet in the laboratory. Free chat conversations were archived, and the transcripts were objectively coded for traditional communication variables, conversational style, and the use of affective language. As predicted, shy adults engaged in significantly fewer spontaneous self-disclosures than did their nonshy counterparts only in the webcam condition. Shy versus nonshy adults did not differ on spontaneous self-disclosures in the no webcam condition. However, context did not influence the use of computer-mediated affective language. Although shy adults used significantly less active and pleasant words than their nonshy counterparts, these differences were not related to webcam condition. The present findings replicate and extend earlier work on shyness, context, and computer-mediated communication to a selected sample of shy adults. Findings suggest that context may influence some, but not all, aspects of social communication in shy adults.

  16. Re-examining the cause of the "Damage Belt" during the 1995 Kobe Earthquake

    NASA Astrophysics Data System (ADS)

    Matsushima, S.; Miyake, H.

    2017-12-01

    The 1995 Kobe earthquake caused devastating disaster which killed 6434 people and collapsed more than 1 million houses. The heavy damage was concentrated in a belt-like area, which was called the "Damage Belt". The cause of the "Damage Belt" was investigated by various researchers and it was found that it was a result of "The Basin-Edge Effect", which is the constructive interference of the direct S-wave with the basin-induced diffracted Rayleigh waves (Kawase, 1996). Matsushima and Kawase (2009) estimated the rupture model of the 1995 Kobe Earthquake by using 3-D reciprocal Green's functions and searching for the best fitting case by grid-search technique assuming plural rectangular strong motion generation areas (SMGAs) and succeeded to reproduce the high PGV area that corresponds to the "Damage Belt". In this study, we re-examine the cause of the "Damage Belt" by combining the estimated rupture model with the up-to-date 3-D velocity structure. The velocity structure of whole Japan has been modeled and is being modified occasionally by the Headquarters for Earthquake Research Promotion using the geological surveys conducted thoroughly by local governments as well as by large research projects since 1995. The very detailed velocity structure of the Osaka basin has been modeled by the Geological Survey of Japan, AIST (Horikawa et al., 2003; Sekiguchi et al., 2008). The aim of this study is to take in account of the different amplification characteristics due to the different velocity structure of the sediment from the seismic bedrock to the surface in Kobe, and investigate its effect to the results of the distribution of PGVs of the simulated ground motions.

  17. The computer-assisted interview In My Shoes can benefit shy preschool children's communication.

    PubMed

    Fängström, Karin; Salari, Raziye; Eriksson, Maria; Sarkadi, Anna

    2017-01-01

    Interviewing children is a cognitively, socially, and emotionally challenging situation, especially for young and shy children. Thus, finding methods that aid rapport and increase these children's communication is important. The present study investigated whether children's verbal and non-verbal communicative behavior developed differently during the rapport phase, depending on whether children were situationally shy or not, and whether the interview was conducted using the computer-assisted interview In My Shoes (IMS) or a Standard verbal interview. The sample consisted of 60 children aged 4 to 5-years-old. The results showed that for the shy children in the IMS group their talkativeness increased and their answer latency decreased including the amount of encouragement the child needed to talk, while no changes were observed for the shy children in the Standard verbal interview group. There were no significant differences in the non-verbal behavior for the shy children regardless of the interview method used. For the non-shy children, overall, the interview method did not affect either the verbal or the non-verbal outcomes. Our findings indicate that IMS can be a useful tool during the rapport-building phase with shy children as it helps these children to improve their verbal communication.

  18. The computer-assisted interview In My Shoes can benefit shy preschool children's communication

    PubMed Central

    Salari, Raziye; Eriksson, Maria; Sarkadi, Anna

    2017-01-01

    Interviewing children is a cognitively, socially, and emotionally challenging situation, especially for young and shy children. Thus, finding methods that aid rapport and increase these children’s communication is important. The present study investigated whether children’s verbal and non-verbal communicative behavior developed differently during the rapport phase, depending on whether children were situationally shy or not, and whether the interview was conducted using the computer-assisted interview In My Shoes (IMS) or a Standard verbal interview. The sample consisted of 60 children aged 4 to 5-years-old. The results showed that for the shy children in the IMS group their talkativeness increased and their answer latency decreased including the amount of encouragement the child needed to talk, while no changes were observed for the shy children in the Standard verbal interview group. There were no significant differences in the non-verbal behavior for the shy children regardless of the interview method used. For the non-shy children, overall, the interview method did not affect either the verbal or the non-verbal outcomes. Our findings indicate that IMS can be a useful tool during the rapport-building phase with shy children as it helps these children to improve their verbal communication. PMID:28813534

  19. The Shy Child. ERIC Digest.

    ERIC Educational Resources Information Center

    Hyson, Marion C.; Van Trieste, Karen

    This ERIC digest: (1) describes types and manifestations of shyness among children; (2) briefly reviews research on genetic, temperamental, and environmental influences on shyness; (3) distinguishes between normal and problematic shyness; and (4) suggests ways for parents and teachers to help the shy child by accepting the whole child, building…

  20. The Best Friendships of Shy/Withdrawn Children: Prevalence, Stability, and Relationship Quality

    PubMed Central

    Rubin, Kenneth H.; Wojslawowicz, Julie C.; Rose-Krasnor, Linda; Booth-LaForce, Cathryn; Burgess, Kim B.

    2013-01-01

    The mutual best friendships of shy/withdrawn and control children were examined for prevalence, stability, best friend’s characteristics, and friendship quality. Using peer nominations of shy/socially withdrawn and aggressive behaviors, two groups of children were identified from a normative sample of fifth-grade children: shy/withdrawn (n = 169) and control (nonaggressive/nonwithdrawn; n = 163). Friendship nominations, teacher reports, and friendship quality data were gathered. Results revealed that shy/withdrawn children were as likely as control children to have mutual stable best friendships. Withdrawn children’s friends were more withdrawn and victimized than were the control children’s best friends; further, similarities in social withdrawal and peer victimization were revealed for withdrawn children and their friends. Withdrawn children and their friends reported lower friendship quality than did control children. Results highlight the importance of both quantitative and qualitative measures of friendship when considering relationships as risk and/or protective factors. PMID:16485175

  1. Disturbed mouse circadian rhythm before the Kobe EQ in 1995

    NASA Astrophysics Data System (ADS)

    Yokoi, Sayoko

    2013-04-01

    Legends of macro-anomalies before large earthquakes have been passed down for generations in Asia. Most of the statements on earthquake precursors are considered unreliable afterthoughts by traditional scientists. However, disturbed biological rhythms in mice were observed before the Kobe EQ in 1995 (Yokoi et al, 2003). The records of unusual mouse behavior before the earthquake were obtained to study biological clock at Institute for Protein Research, Osaka University. It is clarified that the disturbance was very rare phenomena statistically. Similar phenomenon was observed before the Wenchuan earthquake in 2008, too (Li et al, 2009). In the presentation, I will discuss the phenomena as one example of preseismic unusual animal behaviors.

  2. Revolution, Modernity and (Trans)National Shi`i Islam: Rethinking Religious Conversion in Senegal

    PubMed Central

    Leichtman, Mara A.

    2013-01-01

    The establishment of a Shi`i Islamic network in Senegal is one alternative to following the country's dominant Sufi orders. I examine Senegalese conversion narratives and the central role played by the Iranian Revolution, contextualizing life stories (trans)nationally in Senegal's political economy and global networks with Iran and Lebanon. Converts localize foreign religious ideologies into a ‘national’ Islam through the discourse that Shi`i education can bring peace and economic development to Senegal. Senegalese Shi`a perceive that proselytizing, media technologies, and Muslim networking can lead to social, cultural and perhaps even political change through translating the Iranian Revolution into a non-violent reform movement. PMID:23833329

  3. [Validation of SHI Claims Data Exemplified by Gender-specific Diagnoses].

    PubMed

    Hartmann, J; Weidmann, C; Biehle, R

    2016-10-01

    Aim: Use of statutory health insurance (SHI) data in health services research is increasing steadily and questions of validity are gaining importance. Using gender-specific diagnosis as an example, the aim of this study was to estimate the prevalence of implausible diagnosis and demonstrate an internal validation strategy. Method: The analysis is based on the SHI data from Baden-Württemberg for 2012. Subject of validation are gender-specific outpatient diagnoses that mismatch with the gender of the insured. To uncover this implausibility, it is necessary to clarify whether the diagnosis or the gender is wrong. The validation criteria used were the presence of further gender-specific diagnoses, the presence of gender-specific settlement items, the specialization of the physician in charge and the gender assignment of the first name of the insured. To review the quality of the validation, it was verified if the gender was changed during the following year. Results: Around 5.1% of all diagnoses were gender-specific and there was a mismatch between diagnosis and gender in 0.04% of these cases. All validation criteria were useful to sort out implausibility, whereas the last one was the most effective. Only 14% remained unsolved. From the total of 1 145 insured with implausible gender-specific diagnoses, one year later 128 had a new gender (in the data). 119 of these cases were rightly classified as insured with wrong gender and 9 cases were in the unsolved group. This confirms that the validation works well. Conclusion: Implausibility in SHI data is relatively small and can be solved with appropriate validation criteria. When validating SHI data, it is advisable to question all data used critically, to use multiple validation criteria instead of just one and to abandon the idea that reality and the associated data conform to standardized norms. Keeping these aspects in mind, analysis of SHI data is a good starting point for research in health services. © Georg

  4. [Study on SHI's Bian stone comprehensive therapy for rehabilitation after induced abortion].

    PubMed

    Ran, Qing-zhen; Shi, An-li

    2009-02-01

    To explore the rehabilitation effect of SHI's Bian stone comprehensive therapy on the patient after induced abortion. Thirty cases of induced abortion were treated with SHI's Bian stone comprehensive therapy in peri-operative period. Before the operation, scraping therapy was given at the parts of The Urinary Bladder Channel and The Governor Vessel on the back and 30 min after the operation, the patient took a rest in a horizontal position on a mild heat Bian stone blanket and hot compress with a Bian stone plate was given at the lower abdomen. They received thrice return visits respectively on 1, 2, 3 weeks after the operation and SHI's Bian stone comprehensive therapy, including warm massage on The Governor Vessel, scraping the channel, patting Baliao (BL 31, BL 32, BL 33, BL 34), penetration needling Sanyinjiao (SP 6), oblique needling Qihai (CV 6), Guanyuan (CV 4), Zhongji (CV 3), Zigong (EX-CA 1), and the Bian stone plate was placed on the needle hand for warm compress. Colporrhagia, menstrual return, soreness of waist and other symptoms after the operation were observed. After SHI's Bian stone comprehensive therapy, in the patient of induced abortion the colporrhagia volume was less within 3 days after the operation and the colporrhagia stopped more early; of the 30 cases, only 2 has soreness of waist, abdominal pain, fearing cool and other symptoms, and only one case had obviously delayed mestrual cycle. SHI's Bian stone comprehensive therapy used in peri-operative period of induced abortion has a good promoting action on post operative rehabilitation.

  5. Different Influences on Tacrolimus Pharmacokinetics by Coadministrations of Zhi Ke and Zhi Shi in Rats

    PubMed Central

    Lin, Shiuan-Pey; Wu, Ping-Ping; Hou, Yu-Chi; Tsai, Shang-Yuan; Wang, Meng-Ju; Fang, Shih-Hua; Chao, Pei-Dawn Lee

    2011-01-01

    Tacrolimus, an immunosuppressant with narrow therapeutic window, has been used widely in transplant patients. Grapefruit juice and pomelo have been reported to increase the blood levels of tacrolimus. Zhi Ke and Zhi Shi, the ripe peels and unripe fruits of Citrus aurantium which is chemotaxonomically related to grapefruit and pomelo, are in wide use in clinical Chinese medicine. To investigate the possible interaction of these two Citrus herbs with tacrolimus, male Sprague-Dawley rats were orally given tacrolimus (1.5 mg/kg) with and without Zhi Ke and Zhi Shi decoctions in a cross-over design. Blood samples were withdrawn via cardiopuncture at specific time and quantitated by a microparticle enzyme immunoassay. In addition, to explore the mechanism of interaction, LS 180 cell line was used for the transport study of rhodamine 123, a typical substrate of P-glycoprotein (P-gp). The results showed that Zhi Shi significantly decreased the C max and AUC0−t of tacrolimus by 72.4% and 72.0%, respectively, whereas Zhi Ke did not affect tacrolimus pharmacokinetics. LS 180 cell line study indicated that Zhi Shi increased the efflux activity of P-gp, enabling us to explain the decreased oral bioavailability of tacrolimus caused by Zhi Shi. Hence, we suggest that Zhi Shi be contraindicated for transplant patients treated with tacrolimus to reduce the risk of allograft rejection. PMID:21318106

  6. [Contribution of Professor SHI Xue-min's academic thoughts to treatment of stroke].

    PubMed

    Liu, Jian; Fan, Xiao-Nong; Wang, Shu

    2014-01-01

    Based on the thought of Zhishen (a kind of mind regulation), Professor SHI Xue-min, academician of the China Academy of Engineering, found the Xingnao Kaiqiao (to refresh the mind and to cause resuscitation) acupuncture method, which still plays an important role in the acupuncture treatment of wind stroke nowadays. Meanwhile, great importance is attached to the comprehensive treatment of wind stroke. Danqi Piantan capsule (see text) is developed and "wind stroke unit" is set up. In recent years, Professor SHI shifts the center of research to the treatment of hypertension, the risk factor of wind stroke. Taking Renying (ST 9) as the major acupoint, acupuncture with standard measurement and manipulations is established. And good clinical effect has been obtained as well. Therefore, this article focuses on the introduction of Professor SHI Xue-min's contribution to wind stroke treatment.

  7. Discrete Scaling in Earthquake Precursory Phenomena: Evidence in the Kobe Earthquake, Japan

    NASA Astrophysics Data System (ADS)

    Johansen, Anders; Sornette, Didier; Wakita, Hiroshi; Tsunogai, Urumu; Newman, William I.; Saleur, Hubert

    1996-10-01

    We analyze the ion concentration of groundwater issuing from deep wells located near the epicenter of the recent earthquake of magnitude 6.9 near Kobe, Japan, on January 17, 1995. These concentrations are well fitted by log-periodic modulations around a leading power law. The exponent (real and imaginary parts) is very close to those already found for the fits of precursory seismic activity for Loma Prieta and the Aleutian Islands. This brings further support for the general hypothesis that complex critical exponents are a general phenomenon in irreversible self-organizing systems and particularly in rupture and earthquake phenomena. Nous analysons les fluctuations de concentrations ioniques de l'eau issue de puits profonds situés à proximité de l'épicentre du récent tremblement de terre de magnitude 6.9 proche de Kobe au Japon, le 17 janvier 1995. Ces fluctuations sont bien reproduites par des modulations log-périodiques autour d'une loi de puissance. Les parties réelle et imaginaire de l'exposant sont très proches de celles trouvées précédemment pour les tremblements de terre de Loma Prieta et des Iles Aléoutiennes. Ces résultats renforcent l'hypothèse que des exposants critiques complexes sont une propriété générale des phénomènes de croissance irréversible, et en particulier des problèmes de rupture et des tremblements de terre.

  8. SHiP: a new multipurpose beam-dump experiment at the SPS

    NASA Astrophysics Data System (ADS)

    Dijkstra, H. B.

    2016-11-01

    SHiP is an experiment to look for very weakly interacting particles at a new to be constructed beam-dump facility at the CERN SPS. The SHiP Technical Proposal has been submitted to the CERN SPS Committee in April 2015. The 400 GeV/c proton beam extracted from the SPS will be dumped on a heavy target with the aim of integrating 2 × 1020 proton on target in five years. A detector located downstream of the target, based on a long vacuum tank followed by a spectrometer and particle identification detectors, will allow probing a variety of models with light long-lived exotic particles and masses below a few GeV/c2. The main focus will be the physics of the so-called Hidden Portals, i.e. search for Dark Photons, Light scalars and pseudo-scalars, and Heavy Neutral Leptons (HNL). The sensitivity to HNL will allow for the first time to probe, in the mass range between the kaon and the charm meson mass, a coupling range for which Baryogenesis and active neutrino masses could also be explained. Integrated in SHiP is an Emulsion Cloud Chamber, already used in the OPERA experiment, which will allow to study active neutrino cross-sections and angular distributions. In particular SHiP can distinguish between vτ and v¯τ, and their deep inelastic scattering cross sections will be measured with statistics three orders of magnitude larger than currently available.

  9. Spontaneous hemoperitoneum in pregnancy (SHiP) and endometriosis - A systematic review of the recent literature.

    PubMed

    Lier, Marit C I; Malik, Romana F; Ket, Johannes C F; Lambalk, Cornelis B; Brosens, Ivo A; Mijatovic, Velja

    2017-12-01

    Spontaneous Hemoperitoneum in Pregnancy (SHiP), an unprovoked (nontraumatic) intraperitoneal bleeding in pregnancy (up to 42days postpartum), is associated with serious adverse pregnancy outcomes. To evaluate the clinical consequences of SHiP and its association with endometriosis, a systematic review was conducted according to the PRISMA guidelines. PubMed, Embase.com and Thomson Reuters/Web of Science were searched for articles published since the latest review (August 2008) until September 2016. After assessment for eligibility, forty-four articles were included in this systematic review, describing 59 cases of SHiP. Endometriosis was present in 33/59 cases (55.9%), most often diagnosed prior to pregnancy. An association between the severity of SHiP and the stage of endometriosis could not be found. In the majority of cases, SHiP occurred in the third trimester of pregnancy (30/59 cases (50.8%)); women presented with (sub)acute abdominal pain (56/59 cases (94.9%)), hypovolemic shock (28/59 cases (47.5%)) and/or a decreased level of hemoglobin (37/59 cases (62.7%)). Signs of fetal distress were observed in 24/59 cases (40.7%). Imaging confirmed free peritoneal fluid in (37/59 cases (62.7%)). At time of surgery active bleeding was revealed in 51/56 cases (91,1%), originating from endometriotic implants (11/51 cases (21.6%)), ruptured utero-ovarian vessels (29/51 cases (56.8%)), hemorrhagic nodules of decidualized cells (1/51 cases (2.0%)) or a combination (10/51 cases (19.6%)). Median amount of hemoperitoneum was 1600mL (IQR 1000mL-2500mL). From the 45/59 cases (76.3%) in which surgical interventions was carried out during pregnancy, 7/45 cases (15.6%) reported a successful continuation of pregnancy. 5/59 cases reported recurrence of SHiP (recurrence rate 8.5%). The perinatal mortality rate was 26.9% (18/67 fetus), one maternal death was reported (1/59 cases (1,7%)). In conclusion, SHiP is a very serious complication of pregnancy, highly associated with adverse

  10. Social surrogacy and adjustment: exploring the correlates of having a "social helper" for shy and non-shy young adolescents.

    PubMed

    Markovic, Andrea; Bowker, Julie C

    2015-01-01

    A social surrogate is an individual who offers help and comfort in social situations or makes social events more exciting. In this study of 157 young adolescents (55% female; Mage = 13.84 years, SD = 0.75 years), the authors examined whether the linear and curvilinear associations between self-reported social surrogate use and adjustment outcomes (social problems, loneliness, anxiety symptoms, depressive symptoms) varied as a function of shyness and gender, after accounting for the effects of positive friendship quality. Regression analyses revealed that low and high levels of social surrogate use were related to greater social problems for all adolescents. In addition, shyness emerged as a moderator for several curvilinear effects. Specifically, results indicated that (a) high levels of social surrogate use were associated with greater anxiety for adolescents high in shyness; and (b) low levels of social surrogate use were associated with greater depressive symptoms for adolescents low in shyness. Findings highlight the developmental importance of specific types of relationship experiences during early adolescence and point to different implications of social surrogate use for shy and non-shy young adolescents.

  11. Enhancing Contextualized Curriculum: Integrated Identity in Young Shi'i Muslim Arabic-Canadian Students' Social Worlds

    ERIC Educational Resources Information Center

    Al-Fartousi, May

    2016-01-01

    This research explored 10 young female Shi'i Muslim Arabic-Canadian students' experiences associated with wearing the Hijab (headscarf) within their home, community, and predominantly White Canadian public elementary school environments. The in-depth case study sought to address the dearth of information about Shi'is' experiences in schools…

  12. Shy birds play it safe: personality in captivity predicts risk responsiveness during reproduction in the wild

    PubMed Central

    Cole, Ella F.; Quinn, John L.

    2014-01-01

    Despite a growing body of evidence linking personality to life-history variation and fitness, the behavioural mechanisms underlying these relationships remain poorly understood. One mechanism thought to play a key role is how individuals respond to risk. Relatively reactive and proactive (or shy and bold) personality types are expected to differ in how they manage the inherent trade-off between productivity and survival, with bold individuals being more risk-prone with lower survival probability, and shy individuals adopting a more risk-averse strategy. In the great tit (Parus major), the shy–bold personality axis has been well characterized in captivity and linked to fitness. Here, we tested whether ‘exploration behaviour’, a captive assay of the shy–bold axis, can predict risk responsiveness during reproduction in wild great tits. Relatively slow-exploring (shy) females took longer than fast-exploring (bold) birds to resume incubation after a novel object, representing an unknown threat, was attached to their nest-box, with some shy individuals not returning within the 40 min trial period. Risk responsiveness was consistent within individuals over days. These findings provide rare, field-based experimental evidence that shy individuals prioritize survival over reproductive investment, supporting the hypothesis that personality reflects life-history variation through links with risk responsiveness. PMID:24829251

  13. Defining According to Its Essence: An Analysis on the Concept of Tong Shi Education (General Education) in the Native Chinese Context

    ERIC Educational Resources Information Center

    Lu, Yi; Xu, Yuan

    2018-01-01

    The authors review the concept of Tong Shi (Chinese characters omitted) in ancient Chinese philosophical texts, illustrate the Chinese cultural attributes unique to the characters Tong and Shi, and confirm that the name and essence of Tong Shi Education has a clear directivity and irreplaceable coverage to university general education in…

  14. Overexpression of the AtSHI Gene in Poinsettia, Euphorbia pulcherrima, Results in Compact Plants

    PubMed Central

    Islam, M. Ashraful; Lütken, Henrik; Haugslien, Sissel; Blystad, Dag-Ragnar; Torre, Sissel; Rolcik, Jakub; Rasmussen, Søren K.; Olsen, Jorunn E.; Clarke, Jihong Liu

    2013-01-01

    Euphorbia pulcherrima, poinsettia, is a non-food and non-feed vegetatively propagated ornamental plant. Appropriate plant height is one of the most important traits in poinsettia production and is commonly achieved by application of chemical growth retardants. To produce compact poinsettia plants with desirable height and reduce the utilization of growth retardants, the Arabidopsis SHORT INTERNODE (AtSHI) gene controlled by the cauliflower mosaic virus 35S promoter was introduced into poinsettia by Agrobacterium-mediated transformation. Three independent transgenic lines were produced and stable integration of transgene was verified by PCR and Southern blot analysis. Reduced plant height (21–52%) and internode lengths (31–49%) were obtained in the transgenic lines compared to control plants. This correlates positively with the AtSHI transcript levels, with the highest levels in the most dwarfed transgenic line (TL1). The indole-3-acetic acid (IAA) content appeared lower (11–31% reduction) in the transgenic lines compared to the wild type (WT) controls, with the lowest level (31% reduction) in TL1. Total internode numbers, bract numbers and bract area were significantly reduced in all transgenic lines in comparison with the WT controls. Only TL1 showed significantly lower plant diameter, total leaf area and total dry weight, whereas none of the AtSHI expressing lines showed altered timing of flower initiation, cyathia abscission or bract necrosis. This study demonstrated that introduction of the AtSHI gene into poinsettia by genetic engineering can be an effective approach in controlling plant height without negatively affecting flowering time. This can help to reduce or avoid the use of toxic growth retardants of environmental and human health concern. This is the first report that AtSHI gene was overexpressed in poinsettia and transgenic poinsettia plants with compact growth were produced. PMID:23308204

  15. Sensitivity to social and non-social threats in temperamentally shy children at-risk for anxiety.

    PubMed

    LoBue, Vanessa; Pérez-Edgar, Koraly

    2014-03-01

    In the current brief report, we examined threat perception in a group of young children who may be at-risk for anxiety due to extreme temperamental shyness. Results demonstrate specific differences in the processing of social threats: 4- to 7-year-olds in the high-shy group demonstrated a greater bias for social threats (angry faces) than did a comparison group of low-shy children. This pattern did not hold for non-social threats like snakes: Both groups showed an equal bias for the detection of snakes over frogs. The results suggest that children who are tempermentally shy have a heightened sensitivity to social signs of threat early in development. These findings have implications for understanding mechanisms of early threat sensitivity that may predict later socioemotional maladjustment. © 2013 John Wiley & Sons Ltd.

  16. SHiP: a new facility with a dedicated detector for studying tau neutrino properties

    NASA Astrophysics Data System (ADS)

    Komatsu, M.; SHiP Collaboration

    2017-06-01

    SHiP (Search for Hidden Particles) is a new general purpose fixed target facility at the CERN SPS accelerator, with the aim of search for New Physics which has small coupling with standard particles by searching for long lived beyond standard model particles with masses below a few GeV/c2. The SHiP facility is a high intensity beam bump, the 400GeV proton beam extracted from the SPS will be dumped on a heavy target with the aim of integrating 2 ×1020 pot in 5 years. A dedicated detector, based on the OPERA-like ECC (Emulsion Cloud Chamber), will provide tau and anti-tau neutrino detection capability to study ντ and ν‾τ cross-sections with a statistics a few 100 times larger than the DONUT experiment. Moreover, the structure functions F4 and F5 which is only accessible by tau neutrino interactions can be measured first time. SHiP is the unique chance to study tau and anti tau neutrino properties.

  17. A facility to search for hidden particles at the CERN SPS: the SHiP physics case.

    PubMed

    Alekhin, Sergey; Altmannshofer, Wolfgang; Asaka, Takehiko; Batell, Brian; Bezrukov, Fedor; Bondarenko, Kyrylo; Boyarsky, Alexey; Choi, Ki-Young; Corral, Cristóbal; Craig, Nathaniel; Curtin, David; Davidson, Sacha; de Gouvêa, André; Dell'Oro, Stefano; deNiverville, Patrick; Bhupal Dev, P S; Dreiner, Herbi; Drewes, Marco; Eijima, Shintaro; Essig, Rouven; Fradette, Anthony; Garbrecht, Björn; Gavela, Belen; Giudice, Gian F; Goodsell, Mark D; Gorbunov, Dmitry; Gori, Stefania; Grojean, Christophe; Guffanti, Alberto; Hambye, Thomas; Hansen, Steen H; Helo, Juan Carlos; Hernandez, Pilar; Ibarra, Alejandro; Ivashko, Artem; Izaguirre, Eder; Jaeckel, Joerg; Jeong, Yu Seon; Kahlhoefer, Felix; Kahn, Yonatan; Katz, Andrey; Kim, Choong Sun; Kovalenko, Sergey; Krnjaic, Gordan; Lyubovitskij, Valery E; Marcocci, Simone; Mccullough, Matthew; McKeen, David; Mitselmakher, Guenakh; Moch, Sven-Olaf; Mohapatra, Rabindra N; Morrissey, David E; Ovchynnikov, Maksym; Paschos, Emmanuel; Pilaftsis, Apostolos; Pospelov, Maxim; Reno, Mary Hall; Ringwald, Andreas; Ritz, Adam; Roszkowski, Leszek; Rubakov, Valery; Ruchayskiy, Oleg; Schienbein, Ingo; Schmeier, Daniel; Schmidt-Hoberg, Kai; Schwaller, Pedro; Senjanovic, Goran; Seto, Osamu; Shaposhnikov, Mikhail; Shchutska, Lesya; Shelton, Jessie; Shrock, Robert; Shuve, Brian; Spannowsky, Michael; Spray, Andy; Staub, Florian; Stolarski, Daniel; Strassler, Matt; Tello, Vladimir; Tramontano, Francesco; Tripathi, Anurag; Tulin, Sean; Vissani, Francesco; Winkler, Martin W; Zurek, Kathryn M

    2016-12-01

    This paper describes the physics case for a new fixed target facility at CERN SPS. The SHiP (search for hidden particles) experiment is intended to hunt for new physics in the largely unexplored domain of very weakly interacting particles with masses below the Fermi scale, inaccessible to the LHC experiments, and to study tau neutrino physics. The same proton beam setup can be used later to look for decays of tau-leptons with lepton flavour number non-conservation, [Formula: see text] and to search for weakly-interacting sub-GeV dark matter candidates. We discuss the evidence for physics beyond the standard model and describe interactions between new particles and four different portals-scalars, vectors, fermions or axion-like particles. We discuss motivations for different models, manifesting themselves via these interactions, and how they can be probed with the SHiP experiment and present several case studies. The prospects to search for relatively light SUSY and composite particles at SHiP are also discussed. We demonstrate that the SHiP experiment has a unique potential to discover new physics and can directly probe a number of solutions of beyond the standard model puzzles, such as neutrino masses, baryon asymmetry of the Universe, dark matter, and inflation.

  18. Scientific Hybrid Reality Environments (SHyRE): Bringing Field Work into the Laboratory

    NASA Astrophysics Data System (ADS)

    Miller, M. J.; Graff, T.; Young, K.; Coan, D.; Whelley, P.; Richardson, J.; Knudson, C.; Bleacher, J.; Garry, W. B.; Delgado, F.; Noyes, M.; Valle, P.; Buffington, J.; Abercromby, A.

    2018-04-01

    The SHyRE program aims to develop a scientifically-robust analog environment using a new and innovative hybrid reality setting that enables frequent operational testing and rapid protocol development for future planetary exploration.

  19. Evaluating the potential of SHI expression as a compacting tool for ornamental plants.

    PubMed

    Topp, Sine H; Rasmussen, Søren K

    2012-05-01

    Control of plant growth, especially elongation of stems, is important in modern plant production, and many plant species, including cereals, grasses, fruit trees and ornamentals, are regularly treated chemically to control their stature and flowering time. Chemical treatments ensure short, homogenous plants, which are more robust and easy to harvest, transport and sell. Although growth retardants are an expensive and undesirable step in plant production, it is unfortunately necessary at present. Compact growth is desirable in most ornamentals and this trait can be difficult to obtain by traditional breeding. As an alternative, biotechnology could provide plant varieties with optimized growth habits. This review is an introduction to the family of SHI transcription factors, which has recently been used to produce compact plants of very diverse species. The possible functions and regulations of the SHI proteins are discussed, and the potential of using overexpression as means to dwarf plants is assessed. In conclusion the breeding of some species, especially flowering ornamentals, could benefit from this strategy. Furthermore, detailed knowledge about the role of SHI proteins in plant growth and development could help shed more light on the interactions between plant hormone signaling pathways. © 2012 Elsevier Ireland Ltd. All rights reserved.

  20. Prevalence and effects of rape myths in print journalism: the Kobe Bryant case.

    PubMed

    Franiuk, Renae; Seefelt, Jennifer L; Cepress, Sandy L; Vandello, Joseph A

    2008-03-01

    Two studies examine the prevalence and effects of rape myths in the print media covering a real-life case of alleged sexual assault. Study 1 was an archival study of 156 sources from around the country. Articles about the Kobe Bryant case were coded for instances of rape myths, among other variables. Of the articles, 65 mentioned at least one rape myth (with "she's lying" being the single most common myth perpetuated). Study 2 assessed participants' (N = 62) prior knowledge of the Bryant case and exposed them to a myth-endorsing or myth-challenging article about the case. Those exposed to the myth-endorsing article were more likely to believe that Bryant was not guilty and the alleged victim was lying. The implications for victim reporting and reducing sexual assault in general are discussed.

  1. [Professor Shi Qi's experience of applying herbal paste for treating chronic musculoskeletal conditions].

    PubMed

    Li, Xiao-feng; Wang, Yong-jun; Ye, Xiu-lan; Zhou, Chong-jian

    2012-06-01

    Professor Shi Qi is a famous traditional Chinese medicine doctor specializing in orthopaedics and traumatology, who has formatted a set of systematic protocols for the diagnosis and treatment of chronic musculoskeletal conditions. When it is time for using tonics in winter, he advocates applying herbal paste for treating chronic musculoskeletal diseases. This paper introduces Professor Shi Qi's commonly used prescription for treating chronic musculoskeletal conditions and puts forward demands and understandings in concocting herbal paste, experience in herbal paste for treating chronic musculoskeletal diseases such as cervical spondylosis, lumbar disc herniation, lumbar spinal stenosis, lumbar muscle strain, ankylosing spondylitis, osteoporosis, knee osteoarthritis and avascular necrosis of femoral head, and the advantages of herbal paste for treating chronic musculoskeletal conditions as opposed to alternative treatments.

  2. Comparisons of Source Characteristics between Recent Inland Crustal Earthquake Sequences inside and outside of Niigata-Kobe Tectonic Zone, Japan

    NASA Astrophysics Data System (ADS)

    Somei, K.; Asano, K.; Iwata, T.; Miyakoshi, K.

    2012-12-01

    After the 1995 Kobe earthquake, many M7-class inland earthquakes occurred in Japan. Some of those events (e.g., the 2004 Chuetsu earthquake) occurred in a tectonic zone which is characterized as a high strain rate zone by the GPS observation (Sagiya et al., 2000) or dense distribution of active faults. That belt-like zone along the coast in Japan Sea side of Tohoku and Chubu districts, and north of Kinki district, is called as the Niigata-Kobe tectonic zone (NKTZ, Sagiya et al, 2000). We investigate seismic scaling relationship for recent inland crustal earthquake sequences in Japan and compare source characteristics between events occurring inside and outside of NKTZ. We used S-wave coda part for estimating source spectra. Source spectral ratio is obtained by S-wave coda spectral ratio between the records of large and small events occurring close to each other from nation-wide strong motion network (K-NET and KiK-net) and broad-band seismic network (F-net) to remove propagation-path and site effects. We carefully examined the commonality of the decay of coda envelopes between event-pair records and modeled the observed spectral ratio by the source spectral ratio function with assuming omega-square source model for large and small events. We estimated the corner frequencies and seismic moment (ratio) from those modeled spectral ratio function. We determined Brune's stress drops of 356 events (Mw: 3.1-6.9) in ten earthquake sequences occurring in NKTZ and six sequences occurring outside of NKTZ. Most of source spectra obey omega-square source spectra. There is no obvious systematic difference between stress drops of events in NKTZ zone and others. We may conclude that the systematic tendency of seismic source scaling of the events occurred inside and outside of NKTZ does not exist and the average source scaling relationship can be effective for inland crustal earthquakes. Acknowledgements: Waveform data were provided from K-NET, KiK-net and F-net operated by

  3. Preliminary Evaluation of a Social Skills Training and Facilitated Play Early Intervention Programme for Extremely Shy Young Children in China

    ERIC Educational Resources Information Center

    Li, Yan; Coplan, Robert J.; Wang, Yuemin; Yin, Jingtong; Zhu, Jingjing; Gao, Zhuqing; Li, Linhui

    2016-01-01

    The goal of this study was to provide a preliminary evaluation of a social skills and facilitated play early intervention programme to promote social interaction, prosocial behaviours and socio-communicative skills among young extremely shy children in China. Participants were a sample of n = 16 extremely shy young children attending kindergarten…

  4. Reevaluation of the major histocompatibility complex genes of the NOD-progenitor CTS/Shi strain.

    PubMed

    Mathews, C E; Graser, R T; Serreze, D V; Leiter, E H

    2000-01-01

    The common Kd and/or Db alleles of NOD mice contribute to the development of autoimmune diabetes, but their respective contributions are unresolved. The major histocompatibility complex (MHC) of the CTS/Shi mouse, originally designated as H2ct, shares MHC class II region identity with the H2g7 haplotype of NOD mice. However, CTS mice were reported to express distinct but undefined MHC class I gene products. Because diabetes frequency was reduced 56% in females of a NOD stock congenic for H2ct, this partial resistance may have derived from the MHC class I allelic differences. In the present report, we use a combination of serologic analysis and sequencing of MHC class I cDNAs to establish that NOD/Lt and CTS/Shi share a common H2-Kd allele but differ at the H2-D end of the MHC complex. The H2-D allele of CTS/Shi was identified as the rare H2-Ddx recently described in ALR/Lt, another NOD-related strain. These results in mouse model systems show that multiple MHC genes confer diabetes resistance and suggest that at least one of the protective MHC or MHC-linked genes in CTS mice may be at the H2-D end of the complex.

  5. Psychological impact of the pandemic (H1N1) 2009 on general hospital workers in Kobe.

    PubMed

    Matsuishi, Kunitaka; Kawazoe, Ayako; Imai, Hissei; Ito, Atsushi; Mouri, Kentaro; Kitamura, Noboru; Miyake, Keiko; Mino, Koichi; Isobe, Masanori; Takamiya, Shizuo; Hitokoto, Hidefumi; Mita, Tatsuo

    2012-06-01

    In order for hospitals to work efficiently in a pandemic, it is important to know how a pandemic affects the hospital staff. The aim of the present study was to investigate the psychological impact of the pandemic (H1N1) 2009 on hospital workers and how it was affected by the characteristics of the hospital, gender, age, job and work environment. In late June 2009, soon after the pandemic had ended in Kobe city, Japan, a questionnaire was distributed consisting of questions on sociodemographic characteristics, 19 stress-related questions and the Impact of Event Scale (IES) to all 3635 employees at three core general hospitals in Kobe. Exploratory factor analysis was applied to the 19 stress-related questions, and this produced four factors for evaluation (anxiety about infection, exhaustion, workload, and feeling of being protected). Multiple regression models were used to evaluate the association of personal characteristics with each score of the four factors and the IES. Valid answers were received from 1625 employees. Workers at a hospital with intense liaison psychiatric services felt less psychological impact. Workers at a hospital that provided staff with information about the pandemic less frequently, felt unprotected. Workers in work environments that had a high risk of infection felt more anxious and more exhausted. The total IES score was higher in workers in high-risk work environments. It is important for hospitals to protect hospital workers during a pandemic and to rapidly share information about the pandemic. Liaison psychiatric services can help to reduce the impact of the pandemic on hospital workers. © 2012 The Authors. Psychiatry and Clinical Neurosciences © 2012 Japanese Society of Psychiatry and Neurology.

  6. Preservice Teachers' Knowledge of Effective Classroom Management Strategies: Shy or Withdrawn Students.

    ERIC Educational Resources Information Center

    Lacina-Gifford, Lorna J.; Kher, Neelam; Besant, Kyesha

    This study identified preservice teachers' knowledge about effective and ineffective classroom management strategies. A group of 108 preservice teachers at a southern rural public university generated classroom management strategies in response to hypothetical vignettes depicting shy and withdrawn student behavior. Researchers coded the extended…

  7. Shy children are less sensitive to some cues to facial recognition.

    PubMed

    Brunet, Paul M; Mondloch, Catherine J; Schmidt, Louis A

    2010-02-01

    Temperamental shyness in children is characterized by avoidance of faces and eye contact, beginning in infancy. We conducted two studies to determine whether temperamental shyness was associated with deficits in sensitivity to some cues to facial identity. In Study 1, 40 typically developing 10-year-old children made same/different judgments about pairs of faces that differed in the appearance of individual features, the shape of the external contour, or the spacing among features; their parent completed the Colorado childhood temperament inventory (CCTI). Children who scored higher on CCTI shyness made more errors than their non-shy counterparts only when discriminating faces based on the spacing of features. Differences in accuracy were not related to other scales of the CCTI. In Study 2, we showed that these differences were face-specific and cannot be attributed to differences in task difficulty. Findings suggest that shy children are less sensitive to some cues to facial recognition possibly underlying their inability to distinguish certain facial emotions in others, leading to a cascade of secondary negative effects in social behaviour.

  8. Disaster resilience and population ageing: the 1995 Kobe and 2004 Chuetsu earthquakes in Japan.

    PubMed

    Chen, Haili; Maki, Norio; Hayashi, Haruo

    2014-04-01

    This paper provides a framework for evaluating the effects of population ageing on disaster resilience. In so doing, it focuses on the 1995 Kobe and 2004 Chuetsu earthquakes, two major disasters that affected Japan before the 2011 Great East Japan earthquake. It analyses regional population recovery on the basis of pre-disaster and post-recovery demographic characteristics using defined transition patterns of population ageing. The evaluation framework demonstrates that various recovery measures make different contributions to disaster resilience for each transition pattern of population ageing. With reference to regional population ageing, the framework allows for a prediction of disaster resilience, facilitating place vulnerability assessments and potentially informing policy-making strategies for Japan and other countries with ageing populations. © 2014 The Author(s). Disasters © Overseas Development Institute, 2014.

  9. Personality Development Within a Generational Context: Life Course Outcomes of Shy Children.

    PubMed

    Schmidt, Louis A; Tang, Alva; Day, Kimberly L; Lahat, Ayelet; Boyle, Michael H; Saigal, Saroj; Van Lieshout, Ryan J

    2017-08-01

    Studies have shown that shy children born in the 1920s and 1950s had delayed marriage and parenthood, less stable careers, and lower occupational attainment as adults than other children. Do these effects still hold true? We examined demographic and social outcomes of children born between 1977 and 1982 in a prospective longitudinal study. We assessed shyness in childhood (age 8), adolescence (age 12-16), young adulthood (age 22-26), and adulthood (age 30-35), and derived three shyness trajectories (i.e., decreasing, increasing, and low-stable). Social and demographic outcomes for shy children who outgrew their shyness (i.e., decreasing trajectory) were indistinguishable from those who were consistently low on shyness measures. However, a shyness trajectory beginning in adolescence and increasing to adulthood was associated with poorer outcomes, similar to previous studies. These findings highlight the importance of multiple assessments in long-term longitudinal studies and the need to consider personality development within a generational context.

  10. Social Information Processing and Coping Strategies of Shy/Withdrawn and Aggressive Children: Does Friendship Matter?

    PubMed Central

    Burgess, Kim B.; Wojslawowicz, Julie C.; Rubin, Kenneth H.; Rose-Krasnor, Linda; Booth-LaForce, Cathryn

    2013-01-01

    The primary objectives of this investigation were to examine the attributions, emotional reactions, and coping strategies of shy/withdrawn and aggressive girls and boys and to examine whether such social cognitions differ within the relationship context of friendship. Drawn from a sample of 5th and 6th graders (M age = 10.79 years; SD = .77), 78 shy/withdrawn, 76 aggressive, and 85 control children were presented with hypothetical social situations that first involved unfamiliar peers, then a mutual good friend. Results revealed group and gender differences and similarities, depending on the relationship context. From our findings emerges a central message: friends' involvement during interpersonal challenges or stressors mitigates children's attributions, emotions and coping responses. PMID:16611178

  11. SHI induced nano track polymer filters and characterization

    NASA Astrophysics Data System (ADS)

    Vijay, Y. K.

    2009-07-01

    Swift heavy ion irradiation produces damage in polymers in the form of latent tracks. Latent tracks can be enlarged by etching it in a suitable etchant and thus nuclear track etch membrane can be formed for gas permeation / purification in particular for hydrogen where the molecular size is very small. By applying suitable and controlled etching conditions well defined tracks can be formed for specific applications of the membranes. After etching gas permeation method is used for characterizing the tracks. In the present work polycarbonate (PC) of various thickness were irradiated with energetic ion beam at Inter University Accelerator Centre (IUAC), New Delhi. Nuclear tracks were modified by etching the PC in 6N NaOH at 60 (±1) °C from both sides for different times to produce track etch membranes. At critical etch time the etched pits from both the sides meet a rapid increase in gas permeation was observed. Permeability of hydrogen and carbon dioxide has been measured in samples etched for different times. The latent tracks produced by SHI irradiation in the track etch membranes show enhancement of free volume of the polymer. Nano filters are separation devices for the mixture of gases, different ions in the solution and isotopes and isobars separations. The polymer thin films with controlled porosity finding it self as best choice. However, the permeability and selectivity of these polymer based membrane filters are very important at the nano scale separation. The Swift Heavy Ion (SHI) induced nuclear track etched polymeric films with controlled etching have been attempted and characterized as nano scale filters.

  12. Development of a Summarized Health Index (SHI) for use in predicting survival in sea turtles.

    PubMed

    Li, Tsung-Hsien; Chang, Chao-Chin; Cheng, I-Jiunn; Lin, Suen-Chuain

    2015-01-01

    Veterinary care plays an influential role in sea turtle rehabilitation, especially in endangered species. Physiological characteristics, hematological and plasma biochemistry profiles, are useful references for clinical management in animals, especially when animals are during the convalescence period. In this study, these factors associated with sea turtle surviving were analyzed. The blood samples were collected when sea turtles remained alive, and then animals were followed up for surviving status. The results indicated that significantly negative correlation was found between buoyancy disorders (BD) and sea turtle surviving (p < 0.05). Furthermore, non-surviving sea turtles had significantly higher levels of aspartate aminotranspherase (AST), creatinine kinase (CK), creatinine and uric acid (UA) than surviving sea turtles (all p < 0.05). After further analysis by multiple logistic regression model, only factors of BD, creatinine and UA were included in the equation for calculating summarized health index (SHI) for each individual. Through evaluation by receiver operating characteristic (ROC) curve, the result indicated that the area under curve was 0.920 ± 0.037, and a cut-off SHI value of 2.5244 showed 80.0% sensitivity and 86.7% specificity in predicting survival. Therefore, the developed SHI could be a useful index to evaluate health status of sea turtles and to improve veterinary care at rehabilitation facilities.

  13. Development of a Summarized Health Index (SHI) for Use in Predicting Survival in Sea Turtles

    PubMed Central

    Li, Tsung-Hsien; Chang, Chao-Chin; Cheng, I-Jiunn; Lin, Suen-Chuain

    2015-01-01

    Veterinary care plays an influential role in sea turtle rehabilitation, especially in endangered species. Physiological characteristics, hematological and plasma biochemistry profiles, are useful references for clinical management in animals, especially when animals are during the convalescence period. In this study, these factors associated with sea turtle surviving were analyzed. The blood samples were collected when sea turtles remained alive, and then animals were followed up for surviving status. The results indicated that significantly negative correlation was found between buoyancy disorders (BD) and sea turtle surviving (p < 0.05). Furthermore, non-surviving sea turtles had significantly higher levels of aspartate aminotranspherase (AST), creatinine kinase (CK), creatinine and uric acid (UA) than surviving sea turtles (all p < 0.05). After further analysis by multiple logistic regression model, only factors of BD, creatinine and UA were included in the equation for calculating summarized health index (SHI) for each individual. Through evaluation by receiver operating characteristic (ROC) curve, the result indicated that the area under curve was 0.920 ± 0.037, and a cut-off SHI value of 2.5244 showed 80.0% sensitivity and 86.7% specificity in predicting survival. Therefore, the developed SHI could be a useful index to evaluate health status of sea turtles and to improve veterinary care at rehabilitation facilities. PMID:25803431

  14. Do temperamentally shy children process emotion differently than nonshy children? Behavioral, psychophysiological, and gender differences in reticent preschoolers.

    PubMed

    Theall-Honey, Laura A; Schmidt, Louis A

    2006-04-01

    We examined regional brain electrical activity (EEG), heart rate, and subjective responses at rest and during the presentation of videoclips designed to elicit a range of emotions (e.g., sadness, anger, happiness, fear) among a sample of healthy 4-year-old children selected for temperamental shyness. We found that shy children exhibited significantly greater relative right central EEG activation at rest and during the presentation of the fear-eliciting videoclip than nonshy children. Shy females displayed greater relative right mid-frontal EEG activation during the sad, happy, and fear videoclips than shy males who displayed greater relative left mid-frontal EEG activation. These results (1) suggest that recent frontal EEG activation/emotion models might be gender-specific and (2) appear to provide the first empirical evidence for recent theoretical notions linking the origins and maintenance of temperamental shyness in children to difficulty in regulating fear responses. Copyright (c) 2006 Wiley Periodicals, Inc.

  15. Canadian Early-Childhood Educators' Perceptions of Children's Gendered Shy, Aggressive, and Prosocial Behaviors

    ERIC Educational Resources Information Center

    Woods, Heather; Bosacki, Sandra; Coplan, Robert J.

    2016-01-01

    Early childhood educators' (ECE) perceptions of gender roles may contribute to the development of children's own gender-role identities. This qualitative study examined 40 Canadian female ECEs' perceptions of gender and children's shy, aggressive, and prosocial behaviors. Content analysis of extensive interviews revealed three themes: (1) shyness…

  16. Homologues of the Arabidopsis thaliana SHI/STY/LRP1 genes control auxin biosynthesis and affect growth and development in the moss Physcomitrella patens.

    PubMed

    Eklund, D Magnus; Thelander, Mattias; Landberg, Katarina; Ståldal, Veronika; Nilsson, Anders; Johansson, Monika; Valsecchi, Isabel; Pederson, Eric R A; Kowalczyk, Mariusz; Ljung, Karin; Ronne, Hans; Sundberg, Eva

    2010-04-01

    The plant hormone auxin plays fundamental roles in vascular plants. Although exogenous auxin also stimulates developmental transitions and growth in non-vascular plants, the effects of manipulating endogenous auxin levels have thus far not been reported. Here, we have altered the levels and sites of auxin production and accumulation in the moss Physcomitrella patens by changing the expression level of homologues of the Arabidopsis SHI/STY family proteins, which are positive regulators of auxin biosynthesis genes. Constitutive expression of PpSHI1 resulted in elevated auxin levels, increased and ectopic expression of the auxin response reporter GmGH3pro:GUS, and in an increased caulonema/chloronema ratio, an effect also induced by exogenous auxin application. In addition, we observed premature ageing and necrosis in cells ectopically expressing PpSHI1. Knockout of either of the two PpSHI genes resulted in reduced auxin levels and auxin biosynthesis rates in leafy shoots, reduced internode elongation, delayed ageing, a decreased caulonema/chloronema ratio and an increased number of axillary hairs, which constitute potential auxin biosynthesis sites. Some of the identified auxin functions appear to be analogous in vascular and non-vascular plants. Furthermore, the spatiotemporal expression of the PpSHI genes and GmGH3pro:GUS strongly overlap, suggesting that local auxin biosynthesis is important for the regulation of auxin peak formation in non-vascular plants.

  17. The SHiP physics program

    NASA Astrophysics Data System (ADS)

    De Lellis, Giovanni

    2018-05-01

    The discovery of the Higgs boson has fully confirmed the Standard Model of particles and fields. Nevertheless, there are still fundamental phenomena, like the existence of dark matter and the baryon asymmetry of the Universe, which deserve an explanation that could come from the discovery of new particles. The SHiP experiment at CERN meant to search for very weakly coupled particles in the few GeV mass domain has been recently proposed. The existence of such particles, foreseen in different theoretical models beyond the Standard Model, is largely unexplored. A beam dump facility using high intensity 400 GeV protons is a copious source of such unknown particles in the GeV mass range. The beam dump is also a copious source of neutrinos and in particular it is an ideal source of tau neutrinos, the less known particle in the Standard Model. Indeed, tau anti-neutrinos have not been directly observed so far. We report the physics potential of such an experiment including the tau neutrino magnetic moment.

  18. Inferring rate and state friction parameters from a rupture model of the 1995 Hyogo-ken Nanbu (Kobe) Japan earthquake

    USGS Publications Warehouse

    Guatteri, Mariagiovanna; Spudich, P.; Beroza, G.C.

    2001-01-01

    We consider the applicability of laboratory-derived rate- and state-variable friction laws to the dynamic rupture of the 1995 Kobe earthquake. We analyze the shear stress and slip evolution of Ide and Takeo's [1997] dislocation model, fitting the inferred stress change time histories by calculating the dynamic load and the instantaneous friction at a series of points within the rupture area. For points exhibiting a fast-weakening behavior, the Dieterich-Ruina friction law, with values of dc = 0.01-0.05 m for critical slip, fits the stress change time series well. This range of dc is 10-20 times smaller than the slip distance over which the stress is released, Dc, which previous studies have equated with the slip-weakening distance. The limited resolution and low-pass character of the strong motion inversion degrades the resolution of the frictional parameters and suggests that the actual dc is less than this value. Stress time series at points characterized by a slow-weakening behavior are well fitted by the Dieterich-Ruina friction law with values of dc ??? 0.01-0.05 m. The apparent fracture energy Gc can be estimated from waveform inversions more stably than the other friction parameters. We obtain a Gc = 1.5??106 J m-2 for the 1995 Kobe earthquake, in agreement with estimates for previous earthquakes. From this estimate and a plausible upper bound for the local rock strength we infer a lower bound for Dc of about 0.008 m. Copyright 2001 by the American Geophysical Union.

  19. Variation of nitric oxide concentration before the Kobe earthquake, Japan

    NASA Astrophysics Data System (ADS)

    Matsuda, Tokiyoshi; Ikeya, Motoji

    The variation and spatial distribution of the atmospheric concentration of nitric oxide (NO) near the epicenter of the Kobe earthquake at local time 5:46, 17 January 1995 have been studied using data at monitoring stations of the local environmental protection agencies. The concentration of NO 8 days before the earthquake was 199 ppb, about ten times larger than the average peak level of 19 ppb, accompanying the retrospectively reported precursory earthquake lightning, increase of radon concentration in well water and of the counts of electromagnetic (EM) signals. The reported thunderstorm over the Japan Sea about 150 km away was too far for the thunder-generated NO to reach the epicenter area. The concentration of NO was also found to have increased before other major earthquakes (Magnitude>5.0) in Japan. Atmospheric discharges by electric charges or EM waves before earthquakes may have generated NO. However, the generation of NO by human activities of fuel combustion soon after holidays is enormously high every year, which makes it difficult to clearly link the increase with the earthquakes. The increase soon after the earthquake due to traffic jams is clear. The concentration of NO should be monitored at a several sites away from human activities as background data of natural variation and to study its generation at a seismic area before a large earthquake.

  20. Enhancing the Academic Development of Shy Children: A Test of the Efficacy of INSIGHTS

    ERIC Educational Resources Information Center

    O'Connor, Erin E.; Cappella, Elise; McCormick, Meghan P.; McClowry, Sandee G.

    2014-01-01

    This study investigated the efficacy of the INSIGHTS into Children's Temperament intervention in supporting the academic development of shy kindergarten and first-grade children. INSIGHTS is a temperament-based intervention with teacher, parent, and classroom programs. The participants included 345 children from 22 low-income, urban elementary…

  1. Unusual Childhood Waking as a Possible Precursor of the 1995 Kobe Earthquake

    PubMed Central

    Ikeya, Motoji; Whitehead, Neil E.

    2013-01-01

    Simple Summary The paper investigates whether young children may waken before earthquakes through a cause other than foreshocks. It concludes there is statistical evidence for this, but the mechanism best supported is anxiety produced by Ultra Low Frequency (ULF) electromagnetic waves. Abstract Nearly 1,100 young students living in Japan at a range of distances up to 500 km from the 1995 Kobe M7 earthquake were interviewed. A statistically significant abnormal rate of early wakening before the earthquake was found, having exponential decrease with distance and a half value approaching 100 km, but decreasing much slower than from a point source such as an epicentre; instead originating from an extended area of more than 100 km in diameter. Because an improbably high amount of variance is explained, this effect is unlikely to be simply psychological and must reflect another mechanism—perhaps Ultra-Low Frequency (ULF) electromagnetic waves creating anxiety—but probably not 222Rn excess. Other work reviewed suggests these conclusions may be valid for animals in general, not just children, but would be very difficult to apply for practical earthquake prediction. PMID:26487316

  2. One new species of the genus Nigrimacula Shi, Bian & Zhou, 2016 (Orthoptera: Meconematinae) from Sichuan, China.

    PubMed

    Wang, Hai-Jian; Shi, Fu-Ming

    2016-07-01

    The paper describels one new species, i.e. Nigrimacula sichuanensis Wang & Shi, sp. nov. from Sichuan, China, and provides photographs of morphological characters. The type material is deposited in the Museum of Hebei University.

  3. Treatment of Common Cold Patients with the Shi-Cha Capsule: A Multicenter, Double-Blind, Randomized, Placebo-Controlled, Dose-Escalation Trial

    PubMed Central

    Chang, Jing; Dong, Shou-Jin; She, Bin; Zhang, Rui-Ming; Meng, Mao-Bin; Xu, Yan-Ling; Wan, Li-Ling; Shi, Ke-Hua; Pan, Jun-Hun; Mao, Bing

    2012-01-01

    This study was designed to determine the therapeutic efficacy and safety of the Shi-cha capsule, a Chinese herbal formula, in the treatment of patients with wind-cold type common cold. In our multi-center, prospective, double-blind, randomized, placebo-controlled, dose-escalation trial, patients with wind-cold type common cold received 0.6 g of Shi-cha capsule plus 0.6 g placebo (group A), 1.2 g of Shi-cha capsule (group B), or 1.2 g placebo (group C), three times daily for 3 days and followed up to 10 days. The primary end point was all symptom duration. The secondary end points were main symptom duration, minor symptom duration, the changes in cumulative symptom score, main symptom score, and minor symptom score 4 days after the treatment, as well as adverse events. A total of 377 patients were recruited and 360 met the inclusive criteria; 120 patients constituted each treatment group. Compared with patients in group C, patients in groups A and B had significant improvement in the all symptom duration, main symptom duration, minor symptom duration, as well as change from baseline of cumulative symptom score, main symptom score, and minor symptom score at day 4. The symptom durations and scores showed slight superiority of group B over group A, although these differences were not statistically significant. There were no differences in adverse events. The Shi-cha capsule is efficacious and safe for the treatment of patients with wind-cold type common cold. Larger trials are required to fully assess the benefits and safety of this treatment for common cold. PMID:23346193

  4. The SHiP project at CERN

    NASA Astrophysics Data System (ADS)

    De Lellis, G.; SHiP Collaboration

    2016-07-01

    The discovery of the Higgs boson has fully confirmed the Standard Model of particles and fields. Nevertheless, there are still fundamental phenomena, like the existence of dark matter and the baryon asymmetry, which deserve an explanation that could come from the discovery of new particles. Searches for new physics with accelerators are performed at the LHC, looking for high massive particles coupled to matter with ordinary strength. A new experimental facility at CERN meant to search for very weakly coupled particles in the few GeV mass domain has been recently proposed. The existence of such particles, foreseen in different theoretical models beyond the Standard Model, is largely unexplored. A beam dump facility using 400 GeV protons is a copious factory of charmed hadrons and could be used to probe the existence of such particles. The beam dump is also a copious source of neutrinos and in particular it is an ideal source of tau neutrinos, the less known particle in the Standard Model. Indeed, tau anti-neutrinos have not been directly observed so far. We report the physics potential of such an experiment. Resistive Plate Chambers could play a role in the SHiP detector.

  5. The SHiP experiment at CERN

    NASA Astrophysics Data System (ADS)

    Bonivento, Walter M.

    2017-07-01

    The discovery of the Higgs boson has fully confirmed the Standard Model of particles and fields. Nevertheless, there are still fundamental phenomena, like the existence of dark matter and the baryon asymmetry of the Universe, deserving an explanation that could come from the discovery of new particles. Searches for new physics with accelerators are performed at the LHC, looking for high massive particles coupled to matter with ordinary strength. A new experiment at CERN meant to search for very weakly coupled particles in the few GeV mass domain has been recently proposed. The existence of such particles, foreseen in different theoretical models beyond the Standard Model, is largely unexplored. A beam dump facility using high intensity 400 GeV protons is a copious source of such unknown particles in the GeV mass range. The beam dump is also a copious source of neutrinos and in particular it is an ideal source of tau neutrinos, the less known particle in the Standard Model. The neutrino detector can also search for dark matter through its scattering off the electrons. We report the physics potential of the SHiP experiment.

  6. Canadian Elementary School Teachers' Perceptions of Gender Differences in Shy Girls and Boys in the Classroom

    ERIC Educational Resources Information Center

    Akseer, Tabasum; Bosacki, Sandra L.; Rose-Krasnor, Linda; Coplan, Robert J.

    2014-01-01

    Shyness may play a significant role in children's socio-emotional and cognitive competence in the classroom. This qualitative study investigated elementary school teachers' perceptions of the concept of shyness in their students. In particular, we explored teachers' perceptions regarding the role that gender plays in shy children's behaviours, and…

  7. The active muon shield in the SHiP experiment

    NASA Astrophysics Data System (ADS)

    Akmete, A.; Alexandrov, A.; Anokhina, A.; Aoki, S.; Atkin, E.; Azorskiy, N.; Back, J. J.; Bagulya, A.; Baranov, A.; Barker, G. J.; Bay, A.; Bayliss, V.; Bencivenni, G.; Berdnikov, A. Y.; Berdnikov, Y. A.; Bertani, M.; Betancourt, C.; Bezshyiko, I.; Bezshyyko, O.; Bick, D.; Bieschke, S.; Blanco, A.; Boehm, J.; Bogomilov, M.; Bondarenko, K.; Bonivento, W. M.; Boyarsky, A.; Brenner, R.; Breton, D.; Brundler, R.; Bruschi, M.; Büscher, V.; Buonaura, A.; Buontempo, S.; Cadeddu, S.; Calcaterra, A.; Campanelli, M.; Chauveau, J.; Chepurnov, A.; Chernyavsky, M.; Choi, K.-Y.; Chumakov, A.; Ciambrone, P.; Dallavalle, G. M.; D'Ambrosio, N.; D'Appollonio, G.; De Lellis, G.; De Roeck, A.; De Serio, M.; Dedenko, L.; Di Crescenzo, A.; Di Marco, N.; Dib, C.; Dijkstra, H.; Dmitrenko, V.; Domenici, D.; Donskov, S.; Dubreuil, A.; Ebert, J.; Enik, T.; Etenko, A.; Fabbri, F.; Fabbri, L.; Fedin, O.; Fedorova, G.; Felici, G.; Ferro-Luzzi, M.; Fini, R. A.; Fonte, P.; Franco, C.; Fukuda, T.; Galati, G.; Gavrilov, G.; Gerlach, S.; Golinka-Bezshyyko, L.; Golubkov, D.; Golutvin, A.; Gorbunov, D.; Gorbunov, S.; Gorkavenko, V.; Gornushkin, Y.; Gorshenkov, M.; Grachev, V.; Graverini, E.; Grichine, V.; Guler, A. M.; Guz, Yu.; Hagner, C.; Hakobyan, H.; van Herwijnen, E.; Hollnagel, A.; Hosseini, B.; Hushchyn, M.; Iaselli, G.; Iuliano, A.; Jacobsson, R.; Jonker, M.; Kadenko, I.; Kamiscioglu, C.; Kamiscioglu, M.; Khabibullin, M.; Khaustov, G.; Khotyantsev, A.; Kim, S. H.; Kim, V.; Kim, Y. G.; Kitagawa, N.; Ko, J.-W.; Kodama, K.; Kolesnikov, A.; Kolev, D. I.; Kolosov, V.; Komatsu, M.; Konovalova, N.; Korkmaz, M. A.; Korol, I.; Korol'ko, I.; Korzenev, A.; Kovalenko, S.; Krasilnikova, I.; Krivova, K.; Kudenko, Y.; Kurochka, V.; Kuznetsova, E.; Lacker, H. M.; Lai, A.; Lanfranchi, G.; Lantwin, O.; Lauria, A.; Lebbolo, H.; Lee, K. Y.; Lévy, J.-M.; Lopes, L.; Lyubovitskij, V.; Maalmi, J.; Magnan, A.; Maleev, V.; Malinin, A.; Mefodev, A.; Mermod, P.; Mikado, S.; Mikhaylov, Yu.; Milstead, D. A.; Mineev, O.; Montanari, A.; Montesi, M. C.; Morishima, K.; Movchan, S.; Naganawa, N.; Nakamura, M.; Nakano, T.; Novikov, A.; Obinyakov, B.; Ogawa, S.; Okateva, N.; Owen, P. H.; Paoloni, A.; Park, B. D.; Paparella, L.; Pastore, A.; Patel, M.; Pereyma, D.; Petrenko, D.; Petridis, K.; Podgrudkov, D.; Poliakov, V.; Polukhina, N.; Prokudin, M.; Prota, A.; Rademakers, A.; Ratnikov, F.; Rawlings, T.; Razeti, M.; Redi, F.; Ricciardi, S.; Roganova, T.; Rogozhnikov, A.; Rokujo, H.; Rosa, G.; Rovelli, T.; Ruchayskiy, O.; Ruf, T.; Samoylenko, V.; Saputi, A.; Sato, O.; Savchenko, E. S.; Schmidt-Parzefall, W.; Serra, N.; Shakin, A.; Shaposhnikov, M.; Shatalov, P.; Shchedrina, T.; Shchutska, L.; Shevchenko, V.; Shibuya, H.; Shustov, A.; Silverstein, S. B.; Simone, S.; Skorokhvatov, M.; Smirnov, S.; Sohn, J. Y.; Sokolenko, A.; Starkov, N.; Storaci, B.; Strolin, P.; Takahashi, S.; Timiryasov, I.; Tioukov, V.; Tosi, N.; Treille, D.; Tsenov, R.; Ulin, S.; Ustyuzhanin, A.; Uteshev, Z.; Vankova-Kirilova, G.; Vannucci, F.; Venkova, P.; Vilchinski, S.; Villa, M.; Vlasik, K.; Volkov, A.; Voronkov, R.; Wanke, R.; Woo, J.-K.; Wurm, M.; Xella, S.; Yilmaz, D.; Yilmazer, A. U.; Yoon, C. S.; Zaytsev, Yu.

    2017-05-01

    The SHiP experiment is designed to search for very weakly interacting particles beyond the Standard Model which are produced in a 400 GeV/c proton beam dump at the CERN SPS. An essential task for the experiment is to keep the Standard Model background level to less than 0.1 event after 2× 1020 protons on target. In the beam dump, around 1011 muons will be produced per second. The muon rate in the spectrometer has to be reduced by at least four orders of magnitude to avoid muon-induced combinatorial background. A novel active muon shield is used to magnetically deflect the muons out of the acceptance of the spectrometer. This paper describes the basic principle of such a shield, its optimization and its performance.

  8. The SHiP experiment at CERN SPS

    NASA Astrophysics Data System (ADS)

    Di Crescenzo, A.; SHiP Collaboration

    2016-01-01

    SHiP is a new general purpose fixed target facility, whose Technical Proposal has been recently submitted to the CERN SPS Committee. In its initial phase, the 400GeV proton beam extracted from the SPS will be dumped on a heavy target with the aim of integrating 2×1020 pot in 5years. A dedicated detector located downstream of the target, based on a long vacuum tank followed by a spectrometer and particle identification detectors, will allow probing a variety of models with light long-lived exotic particles and masses below a few GeV/c2. The beam dump is also an ideal source of tau neutrinos, the less known particle in the Standard Model. Another dedicated detector, based on the Emulsion Cloud Chamber technology already used in the OPERA experiment, will allow to perform for the first time measurements of the tau neutrino deep inelastic scattering cross section. Tau neutrinos will be distinguished from tau anti-neutrinos, thus providing the first observation of the tau anti-neutrino.

  9. Understanding Relations among Children's Shy and Antisocial/Aggressive Behaviors and Mothers' Parenting: The Role of Maternal Beliefs

    ERIC Educational Resources Information Center

    Evans, Cortney A.; Nelson, Larry J.; Porter, Christin L.; Nelson, David A.; Hart, Craig H.

    2012-01-01

    This study assesses the relationships between children's shy and antisocial/aggressive behaviors and maternal beliefs, and concomitant parenting behaviors. Structural equation models examined 199 mothers' perceptions of aggression and shyness in their preschool-age children (average age = 59.63 months); maternal beliefs (i.e., locus of control,…

  10. MeSHy: Mining unanticipated PubMed information using frequencies of occurrences and concurrences of MeSH terms.

    PubMed

    Theodosiou, T; Vizirianakis, I S; Angelis, L; Tsaftaris, A; Darzentas, N

    2011-12-01

    PubMed is the most widely used database of biomedical literature. To the detriment of the user though, the ranking of the documents retrieved for a query is not content-based, and important semantic information in the form of assigned Medical Subject Headings (MeSH) terms is not readily presented or productively utilized. The motivation behind this work was the discovery of unanticipated information through the appropriate ranking of MeSH term pairs and, indirectly, documents. Such information can be useful in guiding novel research and following promising trends. A web-based tool, called MeSHy, was developed implementing a mainly statistical algorithm. The algorithm takes into account the frequencies of occurrences, concurrences, and the semantic similarities of MeSH terms in retrieved PubMed documents to create MeSH term pairs. These are then scored and ranked, focusing on their unexpectedly frequent or infrequent occurrences. MeSHy presents results through an online interactive interface facilitating further manipulation through filtering and sorting. The results themselves include the MeSH term pairs, along with MeSH categories, the score, and document IDs, all of which are hyperlinked for convenience. To highlight the applicability of the tool, we report the findings of an expert in the pharmacology field on querying the molecularly-targeted drug imatinib and nutrition-related flavonoids. To the best of our knowledge, MeSHy is the first publicly available tool able to directly provide such a different perspective on the complex nature of published work. Implemented in Perl and served by Apache2 at http://bat.ina.certh.gr/tools/meshy/ with all major browsers supported. Copyright © 2011 Elsevier Inc. All rights reserved.

  11. SH-I-048A, AN IN VITRO NONSELECTIVE SUPER-AGONIST AT THE BENZODIAZEPINE SITE OF GABAA RECEPTORS: THE APPROXIMATED ACTIVATION OF RECEPTOR SUBTYPES MAY EXPLAIN BEHAVIORAL EFFECTS

    PubMed Central

    Obradović, Aleksandar Lj.; Joksimović, Srđan; Poe, Michael M.; Ramerstorfer, Joachim; Varagic, Zdravko; Namjoshi, Ojas; Batinić, Bojan; Radulović, Tamara; Marković, Bojan; Roth, Brian; Sieghart, Werner; Cook, James M.; Savić, Miroslav M.

    2014-01-01

    Enormous progress in understanding the role of four populations of benzodiazepine-sensitive GABAA receptors was paralleled by the puzzling findings suggesting that substantial separation of behavioral effects may be accomplished by apparently non-selective modulators. We report on SH-I-048A, a newly-synthesized chiral positive modulator of GABAA receptors characterized by exceptional subnanomolar affinity, high efficacy and non-selectivity. Its influence on behavior was assessed in Wistar rats and contrasted to that obtained with 2 mg/kg diazepam. SH-I-048A reached micromolar concentrations in brain tissue, while the unbound fraction in brain homogenate was around 1.5%. The approximated electrophysiological responses, which estimated free concentrations of SH-I-048A or diazepam are able to elicit, suggested a similarity between the 10 mg/kg dose of the novel ligand and 2 mg/kg diazepam; however, SH-I-048A was relatively more active at α1- and α5-containing GABAA receptors. Behaviorally, SH-I-048A induced sedative, muscle relaxant and ataxic effects, reversed mechanical hyperalgesia 24 hours after injury, while it was devoid of clear anxiolytic actions and did not affect water-maze performance. While lack of clear anxiolytic actions may be connected with an enhanced potentiation at α1-containing GABAA receptors, the observed behavior in the rotarod, water maze and peripheral nerve injury tests was possibly affected by its prominent action at receptors containing the α5 subunit. The current results encourage further innovative approaches aimed at linking in vitro and in vivo data in order to help define fine-tuning mechanisms at four sensitive receptor populations that underlie subtle differences in behavioral profiles of benzodiazepine site ligands. PMID:24472579

  12. Drought-Up-Regulated TaNAC69-1 is a Transcriptional Repressor of TaSHY2 and TaIAA7, and Enhances Root Length and Biomass in Wheat.

    PubMed

    Chen, Dandan; Richardson, Terese; Chai, Shoucheng; Lynne McIntyre, C; Rae, Anne L; Xue, Gang-Ping

    2016-10-01

    A well-known physiological adaptation process of plants encountering drying soil is to achieve water balance by reducing shoot growth and maintaining or promoting root elongation, but little is known about the molecular basis of this process. This study investigated the role of a drought-up-regulated Triticum aestivum NAC69-1 (TaNAC69-1) in the modulation of root growth in wheat. TaNAC69-1 was predominantly expressed in wheat roots at the early vegetative stage. Overexpression of TaNAC69-1 in wheat roots using OsRSP3 (essentially root-specific) and OsPIP2;3 (root-predominant) promoters resulted in enhanced primary seminal root length and a marked increase in maturity root biomass. Competitive growth analysis under water-limited conditions showed that OsRSP3 promoter-driven TaNAC69-1 transgenic lines produced 32% and 35% more above-ground biomass and grains than wild-type plants, respectively. TaNAC69-1 overexpression in the roots down-regulated the expression of TaSHY2 and TaIAA7, which are from the auxin/IAA (Aux/IAA) transcriptional repressor gene family and are the homologs of negative root growth regulators SHY2/IAA3 and IAA7 in Arabidopsis. The expression of TaSHY2 and TaIAA7 in roots was down-regulated by drought stress and up-regulated by cytokinin treatment, which inhibited root growth. DNA binding and transient expression analyses revealed that TaNAC69-1 bound to the promoters of TaSHY2 and TaIAA7, acted as a transcriptional repressor and repressed the expression of reporter genes driven by the TaSHY2 or TaIAA7 promoter. These data suggest that TaNAC69-1 is a transcriptional repressor of TaSHY2 and TaIAA7 homologous to Arabidopsis negative root growth regulators and is likely to be involved in promoting root elongation in drying soil. © The Author 2016. Published by Oxford University Press on behalf of Japanese Society of Plant Physiologists. All rights reserved. For permissions, please email: journals.permissions@oup.com.

  13. Is Silence Golden? Elementary School Teachers' Strategies and Beliefs regarding Hypothetical Shy/Quiet and Exuberant/Talkative Children

    ERIC Educational Resources Information Center

    Coplan, Robert J.; Hughes, Kathleen; Bosacki, Sandra; Rose-Krasnor, Linda

    2011-01-01

    The primary goal of the present study was to examine elementary teachers' strategies, attitudes, and beliefs regarding hypothetical shy (i.e., quiet), exuberant (i.e., overly talkative), and average (i.e., typical) children. We explored whether these strategies and beliefs varied as a function of the gender of the hypothetical child as well as…

  14. Optimising the Active Muon Shield for the SHiP Experiment at CERN

    NASA Astrophysics Data System (ADS)

    Baranov, A.; Burnaev, E.; Derkach, D.; Filatov, A.; Klyuchnikov, N.; Lantwin, O.; Ratnikov, F.; Ustyuzhanin, A.; Zaitsev, A.

    2017-12-01

    The SHiP experiment is designed to search for very weakly interacting particles beyond the Standard Model which are produced in a 400 GeV/c proton beam dump at the CERN SPS. The critical challenge for this experiment is to keep the Standard Model background level negligible. In the beam dump, around 1011 muons will be produced per second. The muon rate in the spectrometer has to be reduced by at least four orders of magnitude to avoid muoninduced backgrounds. It is demonstrated that new improved active muon shield may be used to magnetically deflect the muons out of the acceptance of the spectrometer.

  15. Practical synthesis of Shi's diester fructose derivative for catalytic asymmetric epoxidation of alkenes.

    PubMed

    Nieto, N; Molas, P; Benet-Buchholz, J; Vidal-Ferran, A

    2005-11-25

    [reaction: see text] A practical synthesis of Shi's diester 3 for catalytic asymmetric epoxidations has been developed. The catalyst has been prepared in multigram quantities from D-fructose in four steps with a 66% overall yield. Efficiency, cost, and selectivity aspects of the reagents involved for its preparation have been taken care of during its preparation. The workup procedures have been simplified to the bare minimum, rendering a very practical preparation method. The well-known high efficiency of this catalyst 3 in the epoxidation of alpha,beta-unsaturated carbonyl compounds has also proved to be high in unfunctionalized alkenes.

  16. Effects of Language Context on Ratings of Shy and Unsociable Behaviors in English Language Learning Children

    PubMed Central

    Ash, Andrea C.; Rice, Mabel L.; Redmond, Sean M.

    2014-01-01

    Purpose The primary goal of this study was to explore the effect of the language context on the socially withdrawn behaviors of school aged-children who are English Language Learners (ELLs) from middle to high SES backgrounds. This is one of the first studies to address the frequently confused concepts of shyness and unsociability as independent constructs within the ELL population. This study also investigated the feasibility of an experimental parent and child questionnaire that examines shyness and unsociability across native and English speaking contexts. Method Children and parents (34 ELL and 37 native English speaking) were administered an experimental questionnaire examining shy and unsociable behavior in native language and English-speaking contexts. Results Parents and children from the ELL group reported significantly higher ratings of shy behavior in English versus native language contexts, whereas unsociable ratings did not differ across language contexts. Conclusions Shyness and unsociability are distinguishable behaviors in ELL children and these constructs should be considered when examining withdrawal. Additionally, examining ELL children’s behavior across language contexts provides a valuable method for investigating language influenced behavioral problems. This study demonstrates the need for service providers to evaluate behavior across subtype and language context before pathologizing withdrawal in ELL children. PMID:24687767

  17. Getting to "No": Locating Critical Peace Education within Resistance and Anti-Oppression Pedagogy at a Shi'a Islamic School in Lebanon

    ERIC Educational Resources Information Center

    Zakharia, Zeena

    2017-01-01

    This paper critically engages observations from a school that was aligned with a resistance movement in Lebanon during a post-war period of sustained political violence (2006-2007). Focusing on the pedagogical practices at one community-centered and community-led Shi'a Islamic urban school, the paper draws on extensive ethnographic data to…

  18. [Shi Weishan, the pioneer of the western medicine in Hubei in the Late Qing Dynasty].

    PubMed

    Liu, F W

    2017-07-28

    The Englishman Shi Weishan (Frederick Porter Smith) is the first Christianity medical missionary sent to Central China, who is also the founder of the first mission hospital named 'Hospital of Universal Love' in Hubei. Arrived at Hankou in May 1864, he started medical work in July, and left Hankou in December 1870 because of health problem. In addition to medical mission, he tried to communicate with Chinese doctors in Hankou, then enlightened local people with health knowledge by written several books and articles, which brought some success. He also devoted to the translation of Chinese proper names and also wrote related book.

  19. Shi-style cervical manipulations for cervical radiculopathy

    PubMed Central

    Cui, Xue-jun; Yao, Min; Ye, Xiu-lan; Wang, Ping; Zhong, Wei-hong; Zhang, Rui-chun; Li, Hui-ying; Hu, Zhi-jun; Tang, Zhan-ying; Wang, Wei-min; Qiao, Wei-ping; Sun, Yue-li; Li, Jun; Gao, Yang; Shi, Qi; Wang, Yongjun

    2017-01-01

    Abstract Background: There is a lack of high-quality evidence supporting the use of manipulation therapy for patients with cervical radiculopathy (CR). This study aimed to evaluate the effectiveness of Shi-style cervical manipulations (SCMs) versus mechanical cervical traction (MCT) for CR. Methods: This was a randomized, open-label, controlled trial carried out at 5 hospitals in patients with CR for at least 2 weeks and neck pain. The patients received 6 treatments of SCM (n = 179) or MCT (n = 180) over 2 weeks. The primary outcome was participant-rated disability (neck disability index), measured 2 weeks after randomization. The secondary outcomes were participant-rated pain (visual analog scale) and health-related quality of life (36-Item Short Form Health Survey [SF-36]). Assessments were performed before, during, and after (2, 4, 12, and 24 weeks) intervention. Results: After 2 weeks of treatment, the SCM group showed a greater improvement in participant-rated disability compared with the control group (P = .018). The SCM group reported less disability compared with the control group (P < .001) during the 26-week follow-up. The difference was particularly important at 6 months (mean −28.91 ± 16.43, P < .001). Significant improvements in SF-36 were noted in both groups after 2 weeks of treatment, but there were no differences between the 2 groups. Conclusion: SCM could be a better option than MCT for the treatment of CR-related pain and disability. PMID:28767566

  20. Effects of Climate Change and Fisheries Bycatch on Shy Albatross (Thalassarche cauta) in Southern Australia

    PubMed Central

    2015-01-01

    The impacts of climate change on marine species are often compounded by other stressors that make direct attribution and prediction difficult. Shy albatrosses (Thalassarche cauta) breeding on Albatross Island, Tasmania, show an unusually restricted foraging range, allowing easier discrimination between the influence of non-climate stressors (fisheries bycatch) and environmental variation. Local environmental conditions (rainfall, air temperature, and sea-surface height, an indicator of upwelling) during the vulnerable chick-rearing stage, have been correlated with breeding success of shy albatrosses. We use an age-, stage- and sex-structured population model to explore potential relationships between local environmental factors and albatross breeding success while accounting for fisheries bycatch by trawl and longline fisheries. The model uses time-series of observed breeding population counts, breeding success, adult and juvenile survival rates and a bycatch mortality observation for trawl fishing to estimate fisheries catchability, environmental influence, natural mortality rate, density dependence, and productivity. Observed at-sea distributions for adult and juvenile birds were coupled with reported fishing effort to estimate vulnerability to incidental bycatch. The inclusion of rainfall, temperature and sea-surface height as explanatory variables for annual chick mortality rate was statistically significant. Global climate models predict little change in future local average rainfall, however, increases are forecast in both temperatures and upwelling, which are predicted to have detrimental and beneficial effects, respectively, on breeding success. The model shows that mitigation of at least 50% of present bycatch is required to offset losses due to future temperature changes, even if upwelling increases substantially. Our results highlight the benefits of using an integrated modeling approach, which uses available demographic as well as environmental data

  1. Effects of Climate Change and Fisheries Bycatch on Shy Albatross (Thalassarche cauta) in Southern Australia.

    PubMed

    Thomson, Robin B; Alderman, Rachael L; Tuck, Geoffrey N; Hobday, Alistair J

    2015-01-01

    The impacts of climate change on marine species are often compounded by other stressors that make direct attribution and prediction difficult. Shy albatrosses (Thalassarche cauta) breeding on Albatross Island, Tasmania, show an unusually restricted foraging range, allowing easier discrimination between the influence of non-climate stressors (fisheries bycatch) and environmental variation. Local environmental conditions (rainfall, air temperature, and sea-surface height, an indicator of upwelling) during the vulnerable chick-rearing stage, have been correlated with breeding success of shy albatrosses. We use an age-, stage- and sex-structured population model to explore potential relationships between local environmental factors and albatross breeding success while accounting for fisheries bycatch by trawl and longline fisheries. The model uses time-series of observed breeding population counts, breeding success, adult and juvenile survival rates and a bycatch mortality observation for trawl fishing to estimate fisheries catchability, environmental influence, natural mortality rate, density dependence, and productivity. Observed at-sea distributions for adult and juvenile birds were coupled with reported fishing effort to estimate vulnerability to incidental bycatch. The inclusion of rainfall, temperature and sea-surface height as explanatory variables for annual chick mortality rate was statistically significant. Global climate models predict little change in future local average rainfall, however, increases are forecast in both temperatures and upwelling, which are predicted to have detrimental and beneficial effects, respectively, on breeding success. The model shows that mitigation of at least 50% of present bycatch is required to offset losses due to future temperature changes, even if upwelling increases substantially. Our results highlight the benefits of using an integrated modeling approach, which uses available demographic as well as environmental data

  2. Prevalence of consanguineous marriages among shi'a populations of Lebanon.

    PubMed

    El-Kheshen, Ghadir; Saadat, Mostafa

    2013-09-01

    In genetics, a consanguineous marriage means union between couples who are related as second cousins or closer. The present cross-sectional study was carried out in order to illustrate the prevalence and types of consanguineous marriages in the Shi'a population living in widespread territories in Lebanon including the Bekaa Valley, the south of Lebanon and the southern suburb of Beirut. Data on types of marriages were collected using a simple questionnaire. The total number of couples in the study was 1203. Consanguineous marriage was classified by the degree of relationship between couples. The overall frequency of consanguinity was found to be 28.4%, with first cousin marriages (21.3%) being the most common type followed by first cousins once removed (5.5%), then double first cousins (0.8%). The frequencies of second cousin and beyond second cousin marriages were the same at 0.4% of all the marriages. The mean inbreeding coefficient (α) was estimated at about 0.0161 for the population. There were no significant differences between the three studied territories for frequencies of different types of marriages (p>0.1), nor were there significant differences between the rural and urban areas (p>0.1).

  3. SHI irradiation effect on pure and Mn doped ZnO thin films

    NASA Astrophysics Data System (ADS)

    Khawal, H. A.; Raskar, N. D.; Dole, B. N.

    2017-05-01

    Investigated the structural, surface, electrical and modifications induced by Swift Heavy Ions (SHI) irradiation on pure and Mn substituted ZnO thin films were observed. Thin films of Zn1-xMnxO (x = 0.00, 0.04) were synthesized using the dip coating technique. All thin films irradiated by Li3+ swift heavy ions with fluence 5 × 1013 ions/cm2. The XRD peak reveals that all the samples exhibit wurtzite structures. Surface morphology of samples was investigated by SEM, it was observed that pristine samples of ZnO thin film shows spherical shape but for 4 % Mn substituted ZnO thin film with 5 × 1013 ions/cm2 fluence, it reveals that big grain spherical morphology like structure respectively. I-V characteristics were recorded in the voltage range -5 to 5 V. All curves were passed through origin and nearly linear exhibit ohmic in nature for the films.

  4. SHiP: a new facility with a dedicated detector to search for new neutral particles and studying tau neutrino properties

    NASA Astrophysics Data System (ADS)

    Shevchenko, V.

    2017-12-01

    SHiP (Search for Hidden Particles) is a new general purpose fixed target facility, whose Technical Proposal has been recently reviewed by the CERN SPS Committee and by the CERN Research Board. The two boards recommended that the experiment proceeds further to a Comprehensive Design phase in the context of the new CERNWorking group "Physics Beyond Colliders", aiming at presenting a CERN strategy for the European Strategy meeting of 2019. In the initial phase of SHiP, the 400 GeV proton beam extracted from the SPS will be dumped on a heavy target with the aim of integrating 2×1020 pot in 5 years. A dedicated detector, based on a long vacuum tank followed by a spectrometer and particle identification detectors, will allow probing a variety of models with light long-lived exotic particles and masses below O(10) GeV/c2. The main focus will be the physics of the so-called Hidden Portals, i.e. search for Dark Photons, Light scalars and pseudo-scalars, and Heavy Neutrinos. The sensitivity to Heavy Neutrinos will allow for the first time to probe, in the mass range between the kaon and the charm meson mass, a coupling range for which Baryogenesis and active neutrino masses could also be explained. Another dedicated detector will allow the study of neutrino cross-sections and angular distributions.

  5. Violence against women in the context of war: experiences of Shi'i women and Palestinian refugee women in Lebanon.

    PubMed

    Holt, Maria

    2013-03-01

    In times of war, women are likely to experience, in addition to the "normal" violence of peacetime, random cruelties perpetrated by the enemy against all members of the community. During research conducted with Palestinian refugees and Shi'i Muslims in Lebanon, women described various forms of violence and, in this article, I examine violence suffered by women in the context of conflict from three perspectives: victimization, trauma, and resistance. I argue that traumatic events have the effect of obliterating identity, but they can also strengthen the resolve to resist.

  6. CATS, continuous automated testing of seismological, hydroacoustic, and infrasound (SHI) processing software.

    NASA Astrophysics Data System (ADS)

    Brouwer, Albert; Brown, David; Tomuta, Elena

    2017-04-01

    To detect nuclear explosions, waveform data from over 240 SHI stations world-wide flows into the International Data Centre (IDC) of the Comprehensive Nuclear-Test-Ban Treaty Organization (CTBTO), located in Vienna, Austria. A complex pipeline of software applications processes this data in numerous ways to form event hypotheses. The software codebase comprises over 2 million lines of code, reflects decades of development, and is subject to frequent enhancement and revision. Since processing must run continuously and reliably, software changes are subjected to thorough testing before being put into production. To overcome the limitations and cost of manual testing, the Continuous Automated Testing System (CATS) has been created. CATS provides an isolated replica of the IDC processing environment, and is able to build and test different versions of the pipeline software directly from code repositories that are placed under strict configuration control. Test jobs are scheduled automatically when code repository commits are made. Regressions are reported. We present the CATS design choices and test methods. Particular attention is paid to how the system accommodates the individual testing of strongly interacting software components that lack test instrumentation.

  7. Ethnography for Teachers' Professional Development: Japanese Approach of Investigation on Classroom Activities

    ERIC Educational Resources Information Center

    Matoba, Masami; Sarkar Arani Mohammed Reza

    2006-01-01

    In this paper, we examine how journal and ethnography field notes in Jugyou Kenkyu (lesson study) help teachers to understand the diverse range of talents and abilities of their students. Especially, we focus on how ethnography field note and reflective papers (karate) help teachers to change their assumptions about student learning. The data…

  8. Shy-Drager syndrome. Effect of fludrocortisone and L-threo-3,4-dihydroxyphenylserine on the blood pressure and regional cerebral blood flow.

    PubMed Central

    Matsubara, S; Sawa, Y; Yokoji, H; Takamori, M

    1990-01-01

    In nine cases of Shy-Drager syndrome, the changes in blood pressure and cerebral blood flow on sitting up from a supine position were studied. The influence of fludrocortisone, a synthetic mineralocorticoid, and L-threo-3,4-dihydroxyphenylserine (DOPS), a precursor of norepinephrine, on these changes was examined. On sitting up, the regional cerebral blood flow (rCBF) measured by Xe133 inhalation showed a tendency to decrease. Fludrocortisone reduced the fall of the mean blood pressure significantly. DOPS reduced the fall of both the diastolic blood pressure and rCBF significantly. PMID:2283531

  9. SHiP: a new facility to search for heavy neutrinos and study ντ properties

    NASA Astrophysics Data System (ADS)

    De Serio, M.; SHiP Collaboration

    2016-05-01

    SHiP (Search for Hidden Particles) is a newly designed fixed target facility, proposed at the CERN SPS accelerator, with the aim of complementing searches for New Physics at LHC by searching for light long-lived exotic particles with masses below a few GeV/c2. The sensitivity to Heavy Neutrinos will allow for the first time probing a region of the parameter space where Baryogenesis and active neutrino masses and oscillation could also be explained. A dedicated detector, based on OPERA-like bricks, will provide the first observation of the tau anti-neutrino. Moreover, ντ and ν¯τ cross-sections will be measured with a statistics 1000 times larger than currently available data and will allow extracting the F4 and F5 structure functions, never measured so far. Charm physics studies will be performed with significantly improved accuracy with respect to past experiments.

  10. SHI induced modification in structural, optical, dielectric and thermal properties of poly ethylene oxide films

    NASA Astrophysics Data System (ADS)

    Patel, Gnansagar B.; Bhavsar, Shilpa; Singh, N. L.; Singh, F.; Kulriya, P. K.

    2016-07-01

    Poly ethylene oxide (PEO) films were synthesized by solution cast method. These self-standing films were exposed with 60 MeV C+5 ion and 100 MeV Ni+7 ion at different fluences. SHI induced effect was investigated by employing various techniques. The crystalline size decreased upon irradiation as observed from XRD analysis. FTIR analysis reveals the decrement in the peak intensity upon irradiation. Tauc's method was used to determine the optical band gap (Eg), which shows decreasing trends with increase of fluence. The dielectric properties were investigated in the frequency range 10 Hz to 10 MHz for unirradiated and irradiated films. The dielectric constant remains same for the broad-spectrum of frequency and increases at lower frequency. The dielectric loss also moderately influence as a function of frequency due to irradiation. DSC analysis validated the results of XRD. Scanning electron microscopy (SEM) reveals that there is significant change in the surface morphology due to irradiation.

  11. Studies for the electro-magnetic calorimeter SplitCal for the SHiP experiment at CERN with shower direction reconstruction capability

    NASA Astrophysics Data System (ADS)

    Bonivento, Walter M.

    2018-02-01

    This paper describes the basic ideas and the first simulation results of a new electro-magnetic calorimeter concept, named SplitCal, aimed at optimising the measurement of photon direction in fixed-target experiment configuration, with high photon detection efficiency. This calorimeter was designed for the invariant mass reconstruction of axion-like particles decaying into two photons in the mass range 200 MeV to 1 GeV for the proposed proton beam dump experiment SHiP at CERN. Preliminary results indicate that angular resolutions better than obtained by past experiments can be achieved with this design. An implementation of this concept with real technologies is under study.

  12. Prevalence of swallowing and speech problems in daily life after chemoradiation for head and neck cancer based on cut-off scores of the patient-reported outcome measures SWAL-QOL and SHI.

    PubMed

    Rinkel, Rico N; Verdonck-de Leeuw, Irma M; Doornaert, Patricia; Buter, Jan; de Bree, Remco; Langendijk, Johannes A; Aaronson, Neil K; Leemans, C René

    2016-07-01

    The objective of this study is to assess swallowing and speech outcome after chemoradiation therapy for head and neck cancer, based on the patient-reported outcome measures Swallowing Quality of Life Questionnaire (SWAL-QOL) and Speech Handicap Index (SHI), both provided with cut-off scores. This is a cross-sectional study. Department of Otolaryngology/Head and Neck Surgery of a University Medical Center. Sixty patients, 6 months to 5 years after chemoradiation for head and neck squamous cell carcinoma. Swallowing Quality of Life Questionnaire (SWAL-QOL) and SHI, both validated in Dutch and provided with cut-off scores. Associations were tested between the outcome measures and independent variables (age, gender, tumor stage and site, and radiotherapy technique, time since treatment, comorbidity and food intake). Fifty-two patients returned the SWAL-QOL and 47 the SHI (response rate 87 and 78 %, respectively). Swallowing and speech problems were present in 79 and 55 %, respectively. Normal food intake was noticed in 45, 35 % had a soft diet and 20 % tube feeding. Patients with soft diet and tube feeding reported more swallowing problems compared to patients with normal oral intake. Tumor subsite was significantly associated with swallowing outcome (less problems in larynx/hypopharynx compared to oral/oropharynx). Radiation technique was significantly associated with psychosocial speech problems (less problems in patients treated with IMRT). Swallowing and (to a lesser extent) speech problems in daily life are frequently present after chemoradiation therapy for head and neck cancer. Future prospective studies will give more insight into the course of speech and swallowing problems after chemoradiation and into efficacy of new radiation techniques and swallowing and speech rehabilitation programs.

  13. The use of lisuride in the treatment of multiple system atrophy with autonomic failure (Shy-Drager syndrome).

    PubMed Central

    Lees, A J; Bannister, R

    1981-01-01

    In a controlled trial lisuride, an ergolene derivative with dopamine receptor agonist properties was given maximum tolerated doses (2.4 mg/day) to seven patients with multiple system atrophy with autonomic failure (Shy-Drager syndrome). Improvement in Parkinsonian features occurred in only one patient and another patient who had been deriving marked benefit from levodopa treatment before the study began failed to respond to large doses of lisuride. Psychiatric side effects (including nightmares, isolated visual hallucinations and toxic confusional states) were the dose-limiting factor in six patients. A modest reduction in orthostatic hypotension occurred in two patients, one of whom had experienced an aggravation of this disturbance on levodopa and bromocriptine. Destruction of post-synaptic dopamine receptors and damage to central noradrenergic systems may offer an explanation for the lack of therapeutic effect of lisuride. PMID:7241162

  14. Comparative study of two active faults in different stages of the earthquake cycle in central Japan -The Atera fault (with 1586 Tensho earthquake) and the Nojima fault (with 1995 Kobe earthquake)-

    NASA Astrophysics Data System (ADS)

    Matsuda, T.; Omura, K.; Ikeda, R.

    2003-12-01

    National Research Institute for Earth Science and Disaster Prevention (NIED) has been conducting _gFault zone drilling_h. Fault zone drilling is especially important in understanding the structure, composition, and physical properties of an active fault. In the Chubu district of central Japan, large active faults such as the Atotsugawa (with 1858 Hietsu earthquake) and the Atera (with 1586 Tensho earthquake) faults exist. After the occurrence of the 1995 Kobe earthquake, it has been widely recognized that direct measurements in fault zones by drilling. This time, we describe about the Atera fault and the Nojima fault. Because, these two faults are similar in geological situation (mostly composed of granitic rocks), so it is easy to do comparative study of drilling investigation. The features of the Atera fault, which have been dislocated by the 1586 Tensho earthquake, are as follows. Total length is about 70 km. That general trend is NW45 degree with a left-lateral strike slip. Slip rate is estimated as 3-5 m / 1000 years. Seismicity is very low at present and lithologies around the fault are basically granitic rocks and rhyolite. Six boreholes have been drilled from the depth of 400 m to 630 m. Four of these boreholes (Hatajiri, Fukuoka, Ueno and Kawaue) are located on a line crossing in a direction perpendicular to the Atera fault. In the Kawaue well, mostly fractured and alternating granitic rock continued from the surface to the bottom at 630 m. X-ray fluorescence analysis (XRF) is conducted to estimate the amount of major chemical elements using the glass bead method for core samples. The amounts of H20+ are about from 0.5 to 2.5 weight percent. This fractured zone is also characterized by the logging data such as low resistivity, low P-wave velocity, low density and high neutron porosity. The 1995 Kobe (Hyogo-ken Nanbu) earthquake occurred along the NE-SW-trending Rokko-Awaji fault system, and the Nojima fault appeared on the surface on Awaji Island when this

  15. Shy herbivores forage more efficiently than bold ones regardless of information-processing overload.

    PubMed

    Tan, Ming Kai; Chang, Chia-Chen; Tan, Hugh T W

    2018-04-01

    The neural constraint hypothesis is central to understanding decision-making by foraging herbivorous insects which make decisions less efficiently when they face multiple choices for numerous resource types and/or at high densities instead of a fewer choices. Previous studies have also shown the relationship between personality type and decision-making style. How personality types correlate with foraging efficiency among herbivores is however, largely untested. To answer this question, we used a widespread, polyphagous, floriphilic katydid, Phaneroptera brevis (Orthoptera: Tettigoniidae) and two naturalised, Asteraceae, food plants, Bidens pilosa and Sphagneticola trilobata, as model systems. After we determined each katydid's exploration and boldness levels, we examined its foraging efficiency across different combinations of floral resource choice and density. We showed: (1) For the first time within the Tettigonioidea lineage that this katydid exhibits different personality types in exploration and boldness. (2) Contrary to our prediction, we did not find any support for the neural constraint hypothesis because more floral resource choice at a high density did not reduce foraging efficiency. (3) Surprisingly, bold katydids tend to be less efficient foragers than shy ones. Our findings have enhanced understanding of herbivore behavioural ecology and knowledge to better deal with potential pest herbivores. Copyright © 2018 Elsevier B.V. All rights reserved.

  16. The variation of riverbed material due to tropical storms in Shi-Wen River, Taiwan.

    PubMed

    Lin, Chin-Ping; Wang, Yu-Min; Tfwala, Samkele S; Chen, Ching-Nuo

    2014-01-01

    Taiwan, because of its location, is a flood prone region and is characterised by typhoons which brings about two-thirds to three quarters of the annual rainfall amount. Consequently, enormous flows result in rivers and entrain some fractions of the grains that constitute the riverbed. Hence, the purpose of the study is to quantify the impacts of these enormous flows on the distribution of grain size in riverbeds. The characteristics of riverbed material prior to and after the typhoon season are compared in Shi-Wen River located at southern Taiwan. These include grain size variation, bimodality, and roughness coefficient. A decrease (65%) and increase (50%) in geometric mean size of grains were observed for subsurface and surface bed material, respectively. Geometric standard deviation decreased in all sites after typhoon. Subsurface material was bimodal prior to typhoons and polymodal after. For surface material, modal class is in the gravel class, while after typhoons it shifts towards cobble class. The reduction in geometric mean resulted to a decrease in roughness coefficient by up to 30%. Finally, the relationship of Shields and Froude numbers are studied and a change in the bed form to antidunes and transition form is observed, respectively.

  17. The Variation of Riverbed Material due to Tropical Storms in Shi-Wen River, Taiwan

    PubMed Central

    Lin, Chin-Ping; Tfwala, Samkele S.; Chen, Ching-Nuo

    2014-01-01

    Taiwan, because of its location, is a flood prone region and is characterised by typhoons which brings about two-thirds to three quarters of the annual rainfall amount. Consequently, enormous flows result in rivers and entrain some fractions of the grains that constitute the riverbed. Hence, the purpose of the study is to quantify the impacts of these enormous flows on the distribution of grain size in riverbeds. The characteristics of riverbed material prior to and after the typhoon season are compared in Shi-Wen River located at southern Taiwan. These include grain size variation, bimodality, and roughness coefficient. A decrease (65%) and increase (50%) in geometric mean size of grains were observed for subsurface and surface bed material, respectively. Geometric standard deviation decreased in all sites after typhoon. Subsurface material was bimodal prior to typhoons and polymodal after. For surface material, modal class is in the gravel class, while after typhoons it shifts towards cobble class. The reduction in geometric mean resulted to a decrease in roughness coefficient by up to 30%. Finally, the relationship of Shields and Froude numbers are studied and a change in the bed form to antidunes and transition form is observed, respectively. PMID:24526910

  18. Test of Shi et al. Method to Infer the Magnetic Reconnection Geometry from Spacecraft Data: MHD Simulation with Guide Field and Antiparallel Kinetic Simulation

    NASA Technical Reports Server (NTRS)

    Denton, R.; Sonnerup, B. U. O.; Swisdak, M.; Birn, J.; Drake, J. F.; Heese, M.

    2012-01-01

    When analyzing data from an array of spacecraft (such as Cluster or MMS) crossing a site of magnetic reconnection, it is desirable to be able to accurately determine the orientation of the reconnection site. If the reconnection is quasi-two dimensional, there are three key directions, the direction of maximum inhomogeneity (the direction across the reconnection site), the direction of the reconnecting component of the magnetic field, and the direction of rough invariance (the "out of plane" direction). Using simulated spacecraft observations of magnetic reconnection in the geomagnetic tail, we extend our previous tests of the direction-finding method developed by Shi et al. (2005) and the method to determine the structure velocity relative to the spacecraft Vstr. These methods require data from four proximate spacecraft. We add artificial noise and calibration errors to the simulation fields, and then use the perturbed gradient of the magnetic field B and perturbed time derivative dB/dt, as described by Denton et al. (2010). Three new simulations are examined: a weakly three-dimensional, i.e., quasi-two-dimensional, MHD simulation without a guide field, a quasi-two-dimensional MHD simulation with a guide field, and a two-dimensional full dynamics kinetic simulation with inherent noise so that the apparent minimum gradient was not exactly zero, even without added artificial errors. We also examined variations of the spacecraft trajectory for the kinetic simulation. The accuracy of the directions found varied depending on the simulation and spacecraft trajectory, but all the directions could be found within about 10 for all cases. Various aspects of the method were examined, including how to choose averaging intervals and the best intervals for determining the directions and velocity. For the kinetic simulation, we also investigated in detail how the errors in the inferred gradient directions from the unmodified Shi et al. method (using the unperturbed gradient

  19. Infestation status of head louse and treatment with lindane shampoo in children of primary school and kindergarten in Chinju-shi, Kyongsangnam-do, Korea

    PubMed Central

    Heo, Jung Min; Kim, Hyung Joon; Go, Gi Moon; Lee, Sang Jeong; Jeong, Song Hoan; Ahn, Seung In; Kim, Min Cheol; Kim, Jeong Eun; Song, Hyee Young; Park, Jeong Woon; Kim, Byung Sung; Sohn, Woon-Mok

    2000-01-01

    The infestation status of head louse among children attending primary schools and kindergartens in Chinju-shi, Kyongsangnam-do, Korea, was investigated between June and July 1999. Out of 2,288 children examined, 3.9% of boys (48/1,242) and 23.5% of girls (246/1,046) were infested with nits or adult/nymphs of lice. The effectiveness of lindane shampoo (1% gamma benzene hexachloride solution) was evaluated after one or two time applications to all the children infested. The negative conversion rate of pediculosis was 93.5%. Effective control measures are needed to control and prevent such ectoparasite infestation amongst children. PMID:10743359

  20. Pragmatists, positive communicators, and shy enthusiasts: three viewpoints on Web conferencing in health sciences education.

    PubMed

    Valaitis, Ruta; Akhtar-Danesh, Noori; Eva, Kevin; Levinson, Anthony; Wainman, Bruce

    2007-12-31

    Web conferencing is a synchronous technology that allows coordinated online audio and visual interactions with learners logged in to a central server. Recently, its use has grown rapidly in academia, while research on its use has not kept up. Conferencing systems typically facilitate communication and support for multiple presenters in different locations. A paucity of research has evaluated synchronous Web conferencing in health sciences education. McMaster University Faculty of Health Sciences trialed Wimba's Live Classroom Web conferencing technology to support education and curriculum activities with students and faculty. The purpose of this study was to explore faculty, staff, and student perceptions of Web conferencing as a support for teaching and learning in health sciences. The Live Classroom technology provided features including real-time VoIP audio, an interactive whiteboard, text chat, PowerPoint slide sharing, application sharing, and archiving of live conferences to support student education and curriculum activities. Q-methodology was used to identify unique and common viewpoints of participants who had exposure to Web conferencing to support educational applications during the trial evaluation period. This methodology is particularly useful for research on human perceptions and interpersonal relationships to identify groups of participants with different perceptions. It mixes qualitative and quantitative methods. In a Q-methodology study, the goal is to uncover different patterns of thought rather than their numerical distribution among the larger population. A total of 36 people participated in the study, including medical residents (14), nursing graduate students (11), health sciences faculty (9), and health sciences staff (2). Three unique viewpoints were identified: pragmatists (factor 1), positive communicators (factor 2A), and shy enthusiasts (factor 2B). These factors explained 28% (factor 1) and 11% (factor 2) of the total variance

  1. Mechanosensitivity below Ground: Touch-Sensitive Smell-Producing Roots in the Shy Plant Mimosa pudica.

    PubMed

    Musah, Rabi A; Lesiak, Ashton D; Maron, Max J; Cody, Robert B; Edwards, David; Fowble, Kristen L; Dane, A John; Long, Michael C

    2016-02-01

    The roots of the shy plant Mimosa pudica emit a cocktail of small organic and inorganic sulfur compounds and reactive intermediates into the environment, including SO2, methanesulfinic acid, pyruvic acid, lactic acid, ethanesulfinic acid, propanesulfenic acid, 2-aminothiophenol, S-propyl propane 1-thiosulfinate, phenothiazine, and thioformaldehyde, an elusive and highly unstable compound that, to our knowledge, has never before been reported to be emitted by a plant. When soil around the roots is dislodged or when seedling roots are touched, an odor is detected. The perceived odor corresponds to the emission of higher amounts of propanesulfenic acid, 2-aminothiophenol, S-propyl propane 1-thiosulfinate, and phenothiazine. The mechanosensitivity response is selective. Whereas touching the roots with soil or human skin resulted in odor detection, agitating the roots with other materials such as glass did not induce a similar response. Light and electron microscopy studies of the roots revealed the presence of microscopic sac-like root protuberances. Elemental analysis of these projections by energy-dispersive x-ray spectroscopy revealed them to contain higher levels of K(+) and Cl(-) compared with the surrounding tissue. Exposing the protuberances to stimuli that caused odor emission resulted in reductions in the levels of K(+) and Cl(-) in the touched area. The mechanistic implications of the variety of sulfur compounds observed vis-à-vis the pathways for their formation are discussed. © 2016 American Society of Plant Biologists. All Rights Reserved.

  2. ONRASIA Scientific Information Bulletin. Volume 17, Number 2, Apr-Jun 1992

    DTIC Science & Technology

    1992-06-01

    the Physics Division, Research 7. K Yagi, H . Onuki , S. Sugiyama, Department. Dr. Rehn received his andT. Yamazaki,BunkyoKenkyu 40(5) B.A. in physics at...Pittsburgh in 1962. Aftercomplet- 8. T. Saito, K Katori, M. Nishi, and ing his thesis research in nuclear H . Onuki , Rev. Sci. Instru. 60, 2303...quadrupole resonance studies of para (1989); T. Saito, K Katori, and H . Onuki , dichlorobenzene and related mate- Physica Scripta 41,783 (1990). rials, Dr. Rchn

  3. Use of fault striations and dislocation models to infer tectonic shear stress during the 1995 Hyogo-Ken Nanbu (Kobe) earthquake

    USGS Publications Warehouse

    Spudich, P.; Guatteri, Mariagiovanna; Otsuki, K.; Minagawa, J.

    1998-01-01

    Dislocation models of the 1995 Hyogo-ken Nanbu (Kobe) earthquake derived by Yoshida et al. (1996) show substantial changes in direction of slip with time at specific points on the Nojima and Rokko fault systems, as do striations we observed on exposures of the Nojima fault surface on Awaji Island. Spudich (1992) showed that the initial stress, that is, the shear traction on the fault before the earthquake origin time, can be derived at points on the fault where the slip rake rotates with time if slip velocity and stress change are known at these points. From Yoshida's slip model, we calculated dynamic stress changes on the ruptured fault surfaces. To estimate errors, we compared the slip velocities and dynamic stress changes of several published models of the earthquake. The differences between these models had an exponential distribution, not gaussian. We developed a Bayesian method to estimate the probability density function (PDF) of initial stress from the striations and from Yoshida's slip model. Striations near Toshima and Hirabayashi give initial stresses of about 13 and 7 MPa, respectively. We obtained initial stresses of about 7 to 17 MPa at depths of 2 to 10 km on a subset of points on the Nojima and Rokko fault systems. Our initial stresses and coseismic stress changes agree well with postearthquake stresses measured by hydrofracturing in deep boreholes near Hirabayashi and Ogura on Awaji Island. Our results indicate that the Nojima fault slipped at very low shear stress, and fractional stress drop was complete near the surface and about 32% below depths of 2 km. Our results at depth depend on the accuracy of the rake rotations in Yoshida's model, which are probably correct on the Nojima fault but debatable on the Rokko fault. Our results imply that curved or cross-cutting fault striations can be formed in a single earthquake, contradicting a common assumption of structural geology.

  4. Stratigraphic framework and coal correlation of the Upper Cretaceous Fruitland Formation, Bisti-Ah-Shi-Sle-Pah area, San Juan Basin, New Mexico

    USGS Publications Warehouse

    Flores, Romeo M.; Erpenbeck, Michael F.

    1982-01-01

    This report illustrates and describes the detailed stratigraphic framework and coal correlation of the Upper Cretaceous Fruitland Formation exposed in isolated badlands and along washes within a 20-mile outcrop belt in the Bisti-Ah-Shi-Sle-Pah area, southwestern San Juan Basin, Nex Mexico (see index). The stratigraphic framework showing the vertical and lateral distributions of rock types and the lateral continuity of coal beds is illustrated in cross sections. The cross sections were constructed from 112 stratigraphic sections measured at an average distance of 0.4 mi apart. Each section contained key marker beds (sandstone, coal, and tonstein) that were physically traced to adjacent sections. Each measured section was "hung" on multiple marker beds arranged in a geometric best-fit method that accounts for the differential compaction and facies associations of the deposits. 

  5. A 3D analysis of spatial relationship between geological structure and groundwater profile around Kobe City, Japan: based on ARCGIS 3D Analyst.

    NASA Astrophysics Data System (ADS)

    Shibahara, A.; Tsukamoto, H.; Kazahaya, K.; Morikawa, N.; Takahashi, M.; Takahashi, H.; Yasuhara, M.; Ohwada, M.; Oyama, Y.; Inamura, A.; Handa, H.; Nakama, J.

    2008-12-01

    Kobe city is located on the northern side of Osaka sedimentary basin, Japan, containing 1,000-2,000 m thick Quaternary sediments. After the Hanshin-Awaji Earthquake (January 17, 1995), a number of geological and geophysical surveys were conducted in this region. Then high-temperature anomaly of groundwater accompanied with high Cl concentration was detected along fault systems in this area. In addition, dissolved He in groundwater showed nearly upper mantle-like 3He/4He ratio, although there were no Quaternary volcanic activities in this region. Some recent studies have assumed that these groundwater profiles are related with geological structure because some faults and joints can function as pathways for groundwater flow, and mantle-derived water can upwell through the fault system to the ground surface. To verify these hypotheses, we established 3D geological and hydrological model around Osaka sedimentary basin. Our primary goal is to analyze spatial relationship between geological structure and groundwater profile. In the study region, a number of geological and hydrological datasets, such as boring log data, seismic profiling data, groundwater chemical profile, were reported. We converted these datasets to meshed data on the GIS, and plotted in the three dimensional space to visualize spatial distribution. Furthermore, we projected seismic profiling data into three dimensional space and calculated distance between faults and sampling points, using Visual Basic for Applications (VBA) scripts. All 3D models are converted into VRML format, and can be used as a versatile dataset on personal computer. This research project has been conducted under the research contract with the Japan Nuclear Energy Safety Organization (JNES).

  6. Mechanosensitivity below Ground: Touch-Sensitive Smell-Producing Roots in the Shy Plant Mimosa pudica1[OPEN

    PubMed Central

    Musah, Rabi A.; Lesiak, Ashton D.; Maron, Max J.; Edwards, David; Fowble, Kristen L.; Long, Michael C.

    2016-01-01

    The roots of the shy plant Mimosa pudica emit a cocktail of small organic and inorganic sulfur compounds and reactive intermediates into the environment, including SO2, methanesulfinic acid, pyruvic acid, lactic acid, ethanesulfinic acid, propanesulfenic acid, 2-aminothiophenol, S-propyl propane 1-thiosulfinate, phenothiazine, and thioformaldehyde, an elusive and highly unstable compound that, to our knowledge, has never before been reported to be emitted by a plant. When soil around the roots is dislodged or when seedling roots are touched, an odor is detected. The perceived odor corresponds to the emission of higher amounts of propanesulfenic acid, 2-aminothiophenol, S-propyl propane 1-thiosulfinate, and phenothiazine. The mechanosensitivity response is selective. Whereas touching the roots with soil or human skin resulted in odor detection, agitating the roots with other materials such as glass did not induce a similar response. Light and electron microscopy studies of the roots revealed the presence of microscopic sac-like root protuberances. Elemental analysis of these projections by energy-dispersive x-ray spectroscopy revealed them to contain higher levels of K+ and Cl− compared with the surrounding tissue. Exposing the protuberances to stimuli that caused odor emission resulted in reductions in the levels of K+ and Cl− in the touched area. The mechanistic implications of the variety of sulfur compounds observed vis-à-vis the pathways for their formation are discussed. PMID:26661932

  7. Intertidal pool fish Girella laevifrons (Kyphosidae) shown strong physiological homeostasis but shy personality: The cost of living in hypercapnic habitats.

    PubMed

    Benítez, S; Duarte, C; Opitz, T; Lagos, N A; Pulgar, J M; Vargas, C A; Lardies, M A

    2017-05-15

    Tide pools habitats are naturally exposed to a high degree of environmental variability. The consequences of living in these extreme habitats are not well established. In particular, little it is known about of the effects of hypercanic seawater (i.e. high pCO 2 levels) on marine vertebrates such as intertidal pool fish. The aim of this study was to evaluate the effects of increased pCO 2 on the physiology and behavior in juveniles of the intertidal pool fish Girella laevifrons. Two nominal pCO 2 concentrations (400 and 1600μatm) were used. We found that exposure to hypercapnic conditions did not affect oxygen consumption and absorption efficiency. However, the lateralization and boldness behavior was significantly disrupted in high pCO 2 conditions. In general, a predator-risk cost of boldness is assumed, thus the increased occurrence of shy personality in juvenile fishes may result in a change in the balance of this biological interaction, with significant ecological consequences. Copyright © 2017 Elsevier Ltd. All rights reserved.

  8. [Exploration on academic thoughts of four medical families of acupuncture-moxibustion of the LING, YAN, SHI and SHENG in northern Zhejiang Province].

    PubMed

    Chen, Feng

    2013-12-01

    The academic origin and characteristics of medical families of acupuncture-moxibustion in northern Zhejiang Province were explored in this paper. With acupuncture-moxibustion characteristic of medical families in northern Zhejiang Province such as the LING (see text), the YAN (see text), the SHI (see text) and the SHENG (see text) analyzed and arranged, it was found out that taking the Internal Canon of Medicine as theory basis, their academic thoughts comprehensively absorbed acupuncture-moxibustion theories in all ages, and they continuously made innovations through constant practices, resulting in academic thoughts that focusing on application of acupuncture-moxibustion in clinic, using moxibustion for deficient illness and adopting acupuncture-moxibustion and Chinese herbs for severe and acute patients. The academic thoughts of medical families of acupuncture and moxibustion in northern Zhejiang Province are featured by unique acupoint selection and ma nipulation, thorough moxibustion methods and combined application of Chinese herbs and acupuncture-moxibustion, which is a clinical system of diagnosis and treatment with typical Jiangnan features.

  9. Cumulative approaches to track formation under swift heavy ion (SHI) irradiation: Phenomenological correlation with formation energies of Frenkel pairs

    NASA Astrophysics Data System (ADS)

    Crespillo, M. L.; Agulló-López, F.; Zucchiatti, A.

    2017-03-01

    An extensive survey for the formation energies of Frenkel pairs, as representative candidates for radiation-induced point defects, is presented and discussed in relation to the cumulative mechanisms (CM) of track formation in dielectric materials under swift heavy ion (SHI) irradiation. These mechanisms rely on the generation and accumulation of point defects during irradiation followed by collapse of the lattice once a threshold defect concentration is reached. The physical basis of those approaches has been discussed by Fecht as a defect-assisted transition to an amorphous phase. Although a first quantitative analysis of the CM model was previously performed for LiNbO3 crystals, we have, here, adopted a broader phenomenological approach. It explores the correlation between track formation thresholds and the energies for Frenkel pair formation for a broad range of materials. It is concluded that the threshold stopping powers can be roughly scaled with the energies required to generate a critical Frenkel pair concentration in the order of a few percent of the total atomic content. Finally, a comparison with the predictions of the thermal spike model is discussed within the analytical Szenes approximation.

  10. [Non-pharmaceutical therapy of candidates for geriatric rehabilitation: Non-pharmaceutical therapy prescribed by SHI-accredited doctors after application for outpatient geriatric rehabilitative care].

    PubMed

    Krupp, Sonja; Schnoor, Maike; Lohse, Kristina; Katalinic, Alexander; Willkomm, Martin

    2015-06-01

    The rejection of an application for ambulant geriatric rehabilitation (AGRV) is usually justified by the argument that non-pharmaceutical therapy prescribed by doctors accredited by social housing institutions (SHI) would suffice. The reality in healthcare during the 6 months following an application is unknown. In this study 203 patients who had made an application for AGRV in the second half of 2010 in Flensburg, Lübeck or Ratzeburg were interviewed by telephone. The survey revealed that 25.7% of the applications for AGRV had been rejected. The majority of these patients received no ambulant non-pharmaceutical therapy (e.g. physical therapy, physiotherapy, occupational therapy, speech therapy or psychological therapy), less than 20% received more than 12 therapy sessions and in most cases exclusively physiotherapy. The 141 successful AGRV applicants received additional ambulant therapies of a similar magnitude. The difference between the intensified interdisciplinary therapy offered in the AGRV and additionally and the offer to rejected applicants is substantial.

  11. Novel Human Adenovirus Causing Nosocomial Epidemic Keratoconjunctivitis▿

    PubMed Central

    Ishiko, Hiroaki; Shimada, Yasushi; Konno, Tsunetada; Hayashi, Akio; Ohguchi, Takeshi; Tagawa, Yoshitsugu; Aoki, Koki; Ohno, Shigeaki; Yamazaki, Shudo

    2008-01-01

    In 2000, we encountered cases of nosocomial infections with epidemic keratoconjunctivitis (EKC) at a university hospital in Kobe, in the western part of Japan. Two human adenovirus (HAdV) strains, Kobe-H and Kobe-S, were isolated from patients with nosocomial EKC infection. They were untypeable by existing neutralizing antisera; however, the isolate was neutralized with homologous antisera. We then encountered several cases of EKC due to nosocomial infections in eye clinics in different parts of Japan. A total of 80 HAdVs were isolated from patients with EKC at eight different hospitals. The partial hexon gene sequences of the isolates were determined and compared to those of the prototype strains of 51 serotypes. All isolates had identical partial hexon nucleotide sequences. Phylogenetic analysis classified these isolates into species of HAdV-D. The isolates showed 93.9 to 96.7% nucleotide identity with HAdV-D prototype strains, while all 32 HAdV-D prototype strains ranged from 93.2 to 99.2% identity. The sequences of the loop 2 and fiber knob regions from the representative strain, Kobe-H, were dissimilar in all prototype strains of 51 serotypes. We believe that this virus is a novel serotype of HAdV that causes EKC. PMID:18385435

  12. Chemical profiling approach to evaluate the influence of traditional and simplified decoction methods on the holistic quality of Da-Huang-Xiao-Shi decoction using high-performance liquid chromatography coupled with diode-array detection and time-of-flight mass spectrometry.

    PubMed

    Yan, Xuemei; Zhang, Qianying; Feng, Fang

    2016-04-01

    Da-Huang-Xiao-Shi decoction, consisting of Rheum officinale Baill, Mirabilitum, Phellodendron amurense Rupr. and Gardenia jasminoides Ellis, is a traditional Chinese medicine used for the treatment of jaundice. As described in "Jin Kui Yao Lue", a traditional multistep decoction of Da-Huang-Xiao-Shi decoction was required while simplified one-step decoction was used in recent repsorts. To investigate the chemical difference between the decoctions obtained by the traditional and simplified preparations, a sensitive and reliable approach of high-performance liquid chromatography coupled with diode-array detection and electrospray ionization time-of-flight mass spectrometry was established. As a result, a total of 105 compounds were detected and identified. Analysis of the chromatogram profiles of the two decoctions showed that many compounds in the decoction of simplified preparation had changed obviously compared with those in traditional preparation. The changes of constituents would be bound to cause the differences in the therapeutic effects of the two decoctions. The present study demonstrated that certain preparation methods significantly affect the holistic quality of traditional Chinese medicines and the use of a suitable preparation method is crucial for these medicines to produce special clinical curative effect. This research results elucidated the scientific basis of traditional preparation methods in Chinese medicines. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  13. Application of the precipitation-runoff modeling system to the Ah- shi-sle-pah Wash watershed, San Juan County, New Mexico

    USGS Publications Warehouse

    Hejl, H.R.

    1989-01-01

    The precipitation-runoff modeling system was applied to the 8.21 sq-mi drainage area of the Ah-shi-sle-pah Wash watershed in northwestern New Mexico. The calibration periods were May to September of 1981 and 1982, and the verification period was May to September 1983. Twelve storms were available for calibration and 8 storms were available for verification. For calibration A (hydraulic conductivity estimated from onsite data and other storm-mode parameters optimized), the computed standard error of estimate was 50% for runoff volumes and 72% of peak discharges. Calibration B included hydraulic conductivity in the optimization, which reduced the standard error of estimate to 28 % for runoff volumes and 50% for peak discharges. Optimized values for hydraulic conductivity resulted in reductions from 1.00 to 0.26 in/h and 0.20 to 0.03 in/h for the 2 general soils groups in the calibrations. Simulated runoff volumes using 7 of 8 storms occurring during the verification period had a standard error of estimate of 40% for verification A and 38% for verification B. Simulated peak discharge had a standard error of estimate of 120% for verification A and 56% for verification B. Including the eighth storm which had a relatively small magnitude in the verification analysis more than doubled the standard error of estimating volumes and peaks. (USGS)

  14. Assessment of Benzene-Induced Hematotoxicity Using a Human-Like Hematopoietic Lineage in NOD/Shi-scid/IL-2Rγnull Mice

    PubMed Central

    Takahashi, Masayuki; Tsujimura, Noriyuki; Yoshino, Tomoko; Hosokawa, Masahito; Otsuka, Kensuke; Matsunaga, Tadashi; Nakasono, Satoshi

    2012-01-01

    Despite recent advancements, it is still difficult to evaluate in vivo responses to toxicants in humans. Development of a system that can mimic the in vivo responses of human cells will enable more accurate health risk assessments. A surrogate human hematopoietic lineage can be established in NOD/Shi-scid/IL-2Rγnull (NOG) mice by transplanting human hematopoietic stem/progenitor cells (Hu-NOG mice). Here, we first evaluated the toxic response of human-like hematopoietic lineage in NOG mice to a representative toxic agent, benzene. Flow cytometric analysis showed that benzene caused a significant decrease in the number of human hematopoietic stem/progenitor cells in the bone marrow and the number of human leukocytes in the peripheral blood and hematopoietic organs. Next, we established chimeric mice by transplanting C57BL/6 mouse-derived bone marrow cells into NOG mice (Mo-NOG mice). A comparison of the degree of benzene-induced hematotoxicity in donor-derived hematopoietic lineage cells within Mo-NOG mice indicated that the toxic response of Hu-NOG mice reflected interspecies differences in susceptibilities to benzene. Responses to the toxic effects of benzene were greater in lymphoid cells than in myeloid cells in Mo-NOG and Hu-NOG mice. These findings suggested that Hu-NOG mice may be a powerful in vivo tool for assessing hematotoxicity in humans, while accounting for interspecies differences. PMID:23226520

  15. SHiP: a new facility with a dedicated detector for studying tau-neutrino properties and nucleon structure functions

    NASA Astrophysics Data System (ADS)

    Bick, Daniel; SHiP Collaboration

    2017-09-01

    SHiP is a new general purpose fixed target facility, whose Technical Proposal has been recently reviewed by the CERN SPS Committee, who recommended that the experiment proceeds further to a Comprehensive Design phase. In its initial phase, the 400 GeV proton beam extracted from the SPS will be dumped on a heavy target with the aim of integrating 2 × 1020 pot in 5 years. A dedicated detector downstream of the target will allow to probe a variety of models with light long-lived exotic particles and masses below a few GeV/c2. Another dedicated detector will allow the study of neutrino cross-sections and angular distributions, which was the focus of the poster. ντ deep inelastic scattering cross sections will be measured with a statistics 1000 times larger than currently available, with the extraction of the F 4 and F 5 structure functions, never measured so far and allow for new tests of lepton non-universality with sensitivity to BSM physics. Moreover, ντ ’s will be distinguished from {\\displaystyle \\bar{ν }}τ ’s, thus providing the first observation of the {\\displaystyle \\bar{ν }}τ . With νµ scattering it will be possible to reduce by about 50% the current uncertainty on the strange content of the nucleon in the range of the x variable between 0.05 and 0.3, complementary to LHC measurements. The detector will be based on several techniques developed for the OPERA experiment at LNGS.

  16. The Iron Chancellor and the Fabian

    PubMed Central

    Evans, Robert G.

    2009-01-01

    Adam Wagstaff (2009) reports on a statistical comparison of social health insurance (SHI) versus tax financed (TF) health systems within the OECD. On average, SHI financing is more expensive than TF and yields no better health outcomes. It lowers overall labour force participation and reduces the share of the formal sector. Why, then, is interest in SHI increasing in developing countries? Consider the historical origins for SHI and TF. Bismarck (SHI) was a Prussian aristocrat; Beveridge (TF) was a socialist. TF is inherently egalitarian; SHI adapts readily to the preservation of inequality and privilege in both financing and access to care. This may be the real attraction of SHI in countries with highly unequal income distributions. PMID:20676247

  17. The iron chancellor and the fabian.

    PubMed

    Evans, Robert G

    2009-08-01

    Adam Wagstaff (2009) reports on a statistical comparison of social health insurance (SHI) versus tax financed (TF) health systems within the OECD. On average, SHI financing is more expensive than TF and yields no better health outcomes. It lowers overall labour force participation and reduces the share of the formal sector. Why, then, is interest in SHI increasing in developing countries?Consider the historical origins for SHI and TF. Bismarck (SHI) was a Prussian aristocrat; Beveridge (TF) was a socialist. TF is inherently egalitarian; SHI adapts readily to the preservation of inequality and privilege in both financing and access to care. This may be the real attraction of SHI in countries with highly unequal income distributions.

  18. Validation of the Lithuanian Version of the Speech Handicap Index.

    PubMed

    Pribuisiene, Ruta; Liutkevicius, Vykintas; Pribuisis, Kipras; Uloza, Virgilijus

    2018-05-01

    The objective is to study the cultural adaptation and validation of the Speech Handicap Index (SHI) questionnaire to the Lithuanian language. Cultural adaptation and validation of the translated Lithuanian version of the SHI (SHI-LT) was performed as described by the Scientific Advisory Committee of the Medical Outcomes Trust. The SHI-LT was completed by 46 patients after total laryngectomy and by 60 healthy subjects of the control group. Validity and reliability of the SHI-LT were evaluated. The SHI-LT showed a statistically significant high internal consistency and test-retest reliability (Cronbach's α = 0.96-0.98). Good validity of SHI-LT was reflected by statistically significant (P < 0.001) difference between the mean scores of the patients and control groups (74.7 ± 26.9 and 5.5 ± 6.5, respectively). No age or gender dependence of SHI-LT was found (P > 0.05). Receiver operating characteristic test indicated that SHI-LT scores exceeding 17.0 points (cutoff value) distinguish patients from healthy controls, with a sensitivity of 97.8% and specificity of 95.0%. SHI-LT is considered to be a valid and reliable speech assessment tool for Lithuanian-speaking patients after laryngectomy. Copyright © 2018 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  19. Towards the identification of alkaline phosphatase binding ligands in Li-Dan-Hua-Shi pills: A Box-Behnken design optimized affinity selection approach tandem with UHPLC-Q-TOF/MS analysis.

    PubMed

    Tao, Yi; Huang, Surun; Gu, Xianghui; Li, Weidong; Cai, Baochang

    2018-05-30

    Alkaline phosphatase conjugated magnetic microspheres were synthesized via amide reaction, and employed as an effective adsorbent in affinity selection of binding ligands followed by UHPLC-Q-TOF/MS analysis. The analytical validity of the developed approach was evaluated under optimized conditions and the following figures of merit were obtained: linearity, 0.01-0.5 g L -1 with good determination coefficients (R 2  = 0.9992); limits of detection (LODs), 0.003 g L -1 ; and limits of quantitation (LOQ), 0.01 g L -1 . The precision (RSD%) of the proposed affinity selection approach was studied based on intra-day (0.8%) and inter-day (1.3%) precisions. Finally, the adsorbent was successfully applied to identification of binding ligands in Li-Dan-Hua-Shi pills and good recoveries were obtained in the range from 96.9 to 99.4% (RSDs 1.6-3.0%). Copyright © 2018 Elsevier B.V. All rights reserved.

  20. Review of the genus Pentacentrus Saussure (Orthoptera: Gryllidae: Pentacentrinae) from China .

    PubMed

    Liu, Hao-Yu; Mao, Shao-Li; Shi, Fu-Ming

    2014-07-22

    Four new species of Pentacentrus Gorochov from China are described and illustrated, P. acutiparamerus Liu & Shi sp. nov., P. biflexuous Liu & Shi sp. nov., P. emarginatus Liu & Shi sp. nov. and P. parvulus Liu & Shi sp. nov. A key and a distribution map of the Chinese species of this genus are provided.

  1. [Textual research on Guang dong xin yu (New Sayings of Guangdong) quoted in Ben cao gang mu shi yi (Supplements to Compendium of Materia Medica].

    PubMed

    Zhang, Ruixian; Zhang, Wei; Li, Jian; Liang, Fei

    2014-05-01

    Altogether 15 terms for Guang dong xin yu (New Sayings of Guangdong) were used in Ben cao gang mu shi yi (Supplements to Compendium of Materia Medica), including Yue yu (Cantonese sayings), Chong yu (Sayings from Insect Drug), Jie yu (Sayings from Crustacean Drug), Xin yu (New Sayings), Yue hai xiang yu (Fragrant Sayings from Cantonese Region), Yue zhi mu yu (Sayings from Plants in Cantonese Annals), Guang dong suo yu (Trivial Sayings from Guangdong), Yue shan lu (Records of Cantonese Mountains), Yue lu (Cantonese Records), Jiao guang lu (Joint Guangdong Records), Yue cao zhi (Records of Cantonese Grasses), Guang guo lu (Records of Guangdong Fruits), Nan yue suo ji (Trivial Records of Southern Canton), Guang zhi (Guangdong Records), Yue zhi (Cantonese Records) etc. dealing with 57 sorts of drugs (with individual overlapping ones), the author of Xin yu was Qu Dajun, a surviving fogy of the Ming Dynasty actively involved in the activities to restore the old dynasty and resist the Qing Dynasty, and was persecuted in the literary inquisition in which his works were burnt so that Zhao Xuemin, when quoting his texts, had to go in a roundabout way.

  2. Engineering hyperthermophilic archaeon Pyrococcus furiosus to overproduce its cytoplasmic [NiFe]-hydrogenase.

    PubMed

    Chandrayan, Sanjeev K; McTernan, Patrick M; Hopkins, R Christopher; Sun, Junsong; Jenney, Francis E; Adams, Michael W W

    2012-01-27

    The cytoplasmic hydrogenase (SHI) of the hyperthermophilic archaeon Pyrococcus furiosus is an NADP(H)-dependent heterotetrameric enzyme that contains a nickel-iron catalytic site, flavin, and six iron-sulfur clusters. It has potential utility in a range of bioenergy systems in vitro, but a major obstacle in its use is generating sufficient amounts. We have engineered P. furiosus to overproduce SHI utilizing a recently developed genetic system. In the overexpression (OE-SHI) strain, transcription of the four-gene SHI operon was under the control of a strong constitutive promoter, and a Strep-tag II was added to the N terminus of one subunit. OE-SHI and wild-type P. furiosus strains had similar rates of growth and H(2) production on maltose. Strain OE-SHI had a 20-fold higher transcription of the polycistronic hydrogenase mRNA encoding SHI, and the specific activity of the cytoplasmic hydrogenase was ∼10-fold higher when compared with the wild-type strain, although the expression levels of genes encoding processing and maturation of SHI were the same in both strains. Overexpressed SHI was purified by a single affinity chromatography step using the Strep-tag II, and it and the native form had comparable activities and physical properties. Based on protein yield per gram of cells (wet weight), the OE-SHI strain yields a 100-fold higher amount of hydrogenase when compared with the highest homologous [NiFe]-hydrogenase system previously reported (from Synechocystis). This new P. furiosus system will allow further engineering of SHI and provide hydrogenase for efficient in vitro biohydrogen production.

  3. Engineering Hyperthermophilic Archaeon Pyrococcus furiosus to Overproduce Its Cytoplasmic [NiFe]-Hydrogenase*

    PubMed Central

    Chandrayan, Sanjeev K.; McTernan, Patrick M.; Hopkins, R. Christopher; Sun, Junsong; Jenney, Francis E.; Adams, Michael W. W.

    2012-01-01

    The cytoplasmic hydrogenase (SHI) of the hyperthermophilic archaeon Pyrococcus furiosus is an NADP(H)-dependent heterotetrameric enzyme that contains a nickel-iron catalytic site, flavin, and six iron-sulfur clusters. It has potential utility in a range of bioenergy systems in vitro, but a major obstacle in its use is generating sufficient amounts. We have engineered P. furiosus to overproduce SHI utilizing a recently developed genetic system. In the overexpression (OE-SHI) strain, transcription of the four-gene SHI operon was under the control of a strong constitutive promoter, and a Strep-tag II was added to the N terminus of one subunit. OE-SHI and wild-type P. furiosus strains had similar rates of growth and H2 production on maltose. Strain OE-SHI had a 20-fold higher transcription of the polycistronic hydrogenase mRNA encoding SHI, and the specific activity of the cytoplasmic hydrogenase was ∼10-fold higher when compared with the wild-type strain, although the expression levels of genes encoding processing and maturation of SHI were the same in both strains. Overexpressed SHI was purified by a single affinity chromatography step using the Strep-tag II, and it and the native form had comparable activities and physical properties. Based on protein yield per gram of cells (wet weight), the OE-SHI strain yields a 100-fold higher amount of hydrogenase when compared with the highest homologous [NiFe]-hydrogenase system previously reported (from Synechocystis). This new P. furiosus system will allow further engineering of SHI and provide hydrogenase for efficient in vitro biohydrogen production. PMID:22157005

  4. Life Course Sequelae of Childhood Shyness in Sweden: Comparison with the United States.

    ERIC Educational Resources Information Center

    Kerr, Margaret; And Others

    1996-01-01

    Related Swedish mothers' ratings of their children's shyness with the children's later timing of marriage and parenthood and career success. Shy boys married and became fathers later than non-shy boys, but their careers were not affected by shyness. Shy girls married and became mothers at the same time as non-shy girls. Compared results with…

  5. Human Babesiosis in Japan: Epizootiologic Survey of Rodent Reservoir and Isolation of New Type of Babesia microti-Like Parasite

    PubMed Central

    Tsuji, Masayoshi; Wei, Qiang; Zamoto, Aya; Morita, Chiharu; Arai, Satoru; Shiota, Tsunezo; Fujimagari, Masato; Itagaki, Asao; Fujita, Hiromi; Ishihara, Chiaki

    2001-01-01

    We have carried out epizootiologic surveys at various sites in Japan to investigate wild animals that serve as reservoirs for the agents of human babesiosis in the country. Small mammals comprising six species, Apodemus speciosus, Apodemus argenteus, Clethrionomys rufocanus, Eothenomys smithii, Crocidura dsinezumi, and Sorex unguiculatus, were trapped at various places, including Hokkaido, Chiba, Shiga, Hyogo, Shimane, and Tokushima Prefectures. Animals harboring Babesia microti-like parasites were detected in all six prefectures. Inoculation of their blood samples into hamsters gave rise to a total of 20 parasite isolates; 19 were from A. speciosus, and the other 1 was from C. rufocanus. Sequencing of the parasite small-subunit rRNA gene (rDNA) sequence revealed that 2 of the 20 isolates were classified as Kobe type because their rDNAs were identical to that of the Kobe strain (the strain from the Japanese index case). The other 18 isolates were classified as a new type, designated the Hobetsu type, because they all shared an identical rDNA sequence which differed significantly from both that of Kobe-type isolates and that of northeastern United States B. microti (U.S. type). The parasites with Kobe-, Hobetsu- and U.S.-type rDNAs were phylogenetically closely related to each other but clearly different from each other antigenically. The isolates from rodents were demonstrated to be infective for human erythrocytes by inoculation into SCID mice whose erythrocytes had been replaced with human erythrocytes. The results suggest that a new type of B. microti-like parasite, namely, the Hobetsu type, is the major one which is prevalent among Japanese wild rodents, that A. speciosus serves as a major reservoir for both Kobe- and Hobetsu-type B. microti-like parasites, and that C. rufocanus may also be an additional reservoir on Hokkaido Island. PMID:11724838

  6. Adaptor protein complex 4 deficiency causes severe autosomal-recessive intellectual disability, progressive spastic paraplegia, shy character, and short stature.

    PubMed

    Abou Jamra, Rami; Philippe, Orianne; Raas-Rothschild, Annick; Eck, Sebastian H; Graf, Elisabeth; Buchert, Rebecca; Borck, Guntram; Ekici, Arif; Brockschmidt, Felix F; Nöthen, Markus M; Munnich, Arnold; Strom, Tim M; Reis, Andre; Colleaux, Laurence

    2011-06-10

    Intellectual disability inherited in an autosomal-recessive fashion represents an important fraction of severe cognitive-dysfunction disorders. Yet, the extreme heterogeneity of these conditions markedly hampers gene identification. Here, we report on eight affected individuals who were from three consanguineous families and presented with severe intellectual disability, absent speech, shy character, stereotypic laughter, muscular hypotonia that progressed to spastic paraplegia, microcephaly, foot deformity, decreased muscle mass of the lower limbs, inability to walk, and growth retardation. Using a combination of autozygosity mapping and either Sanger sequencing of candidate genes or next-generation exome sequencing, we identified one mutation in each of three genes encoding adaptor protein complex 4 (AP4) subunits: a nonsense mutation in AP4S1 (NM_007077.3: c.124C>T, p.Arg42(∗)), a frameshift mutation in AP4B1 (NM_006594.2: c.487_488insTAT, p.Glu163_Ser739delinsVal), and a splice mutation in AP4E1 (NM_007347.3: c.542+1_542+4delGTAA, r.421_542del, p.Glu181Glyfs(∗)20). Adaptor protein complexes (AP1-4) are ubiquitously expressed, evolutionarily conserved heterotetrameric complexes that mediate different types of vesicle formation and the selection of cargo molecules for inclusion into these vesicles. Interestingly, two mutations affecting AP4M1 and AP4E1 have recently been found to cause cerebral palsy associated with severe intellectual disability. Combined with previous observations, these results support the hypothesis that AP4-complex-mediated trafficking plays a crucial role in brain development and functioning and demonstrate the existence of a clinically recognizable syndrome due to deficiency of the AP4 complex. Copyright © 2011 The American Society of Human Genetics. Published by Elsevier Inc. All rights reserved.

  7. Adaptor Protein Complex 4 Deficiency Causes Severe Autosomal-Recessive Intellectual Disability, Progressive Spastic Paraplegia, Shy Character, and Short Stature

    PubMed Central

    Abou Jamra, Rami; Philippe, Orianne; Raas-Rothschild, Annick; Eck, Sebastian H.; Graf, Elisabeth; Buchert, Rebecca; Borck, Guntram; Ekici, Arif; Brockschmidt, Felix F.; Nöthen, Markus M.; Munnich, Arnold; Strom, Tim M.; Reis, Andre; Colleaux, Laurence

    2011-01-01

    Intellectual disability inherited in an autosomal-recessive fashion represents an important fraction of severe cognitive-dysfunction disorders. Yet, the extreme heterogeneity of these conditions markedly hampers gene identification. Here, we report on eight affected individuals who were from three consanguineous families and presented with severe intellectual disability, absent speech, shy character, stereotypic laughter, muscular hypotonia that progressed to spastic paraplegia, microcephaly, foot deformity, decreased muscle mass of the lower limbs, inability to walk, and growth retardation. Using a combination of autozygosity mapping and either Sanger sequencing of candidate genes or next-generation exome sequencing, we identified one mutation in each of three genes encoding adaptor protein complex 4 (AP4) subunits: a nonsense mutation in AP4S1 (NM_007077.3: c.124C>T, p.Arg42∗), a frameshift mutation in AP4B1 (NM_006594.2: c.487_488insTAT, p.Glu163_Ser739delinsVal), and a splice mutation in AP4E1 (NM_007347.3: c.542+1_542+4delGTAA, r.421_542del, p.Glu181Glyfs∗20). Adaptor protein complexes (AP1-4) are ubiquitously expressed, evolutionarily conserved heterotetrameric complexes that mediate different types of vesicle formation and the selection of cargo molecules for inclusion into these vesicles. Interestingly, two mutations affecting AP4M1 and AP4E1 have recently been found to cause cerebral palsy associated with severe intellectual disability. Combined with previous observations, these results support the hypothesis that AP4-complex-mediated trafficking plays a crucial role in brain development and functioning and demonstrate the existence of a clinically recognizable syndrome due to deficiency of the AP4 complex. PMID:21620353

  8. Tracing the locality of prisoners and workers at the Mausoleum of Qin Shi Huang: First Emperor of China (259-210 BC)

    PubMed Central

    Ma, Ying; Fuller, Benjamin T.; Sun, Weigang; Hu, Songmei; Chen, Liang; Hu, Yaowu; Richards, Michael P.

    2016-01-01

    The mausoleum complex of the First Emperor of China, Qin Shi Huang (259-210 BC), is one of the most famous and important archaeological sites in China, yet questions remain as to how it was constructed and by whom. Here we present isotopic results of individuals from the Liyi (n = 146) and Shanren sites (n = 14), both associated with the mausoleum complex. Those buried at Liyi represent the local workers/inhabitants of the Qin population, and the δ13C (−8.7 ± 1.5%) and δ15N (10.3 ± 0.7%) values indicate that they consumed predominately millet and/or domestic animals fed millet. In contrast, the Shanren individuals were prisoners forced to construct the mausoleum (found buried haphazardly in a mass grave and some in iron leg shackles), and their δ13C (−15.4 ± 2.9%) and δ15N (8.0 ± 0.6%) results indicate a more mixed C3/C4 diet, with possibly less domestic animals and more wild game protein consumed. This pattern of decreased millet consumption is also characteristic of archaeological sites from southern China, and possible evidence the Shanren prisoners originated from this region (possibly the ancient Chu state located in modern day Hubei Province and parts of Hunan and Anhui Provinces). Further, this finding is in agreement with historical sources and is supported by previous ancient DNA evidence that the mausoleum workers had diverse origins, with many genetically related to southern Chinese groups. PMID:27253909

  9. Tracing the locality of prisoners and workers at the Mausoleum of Qin Shi Huang: First Emperor of China (259-210 BC)

    NASA Astrophysics Data System (ADS)

    Ma, Ying; Fuller, Benjamin T.; Sun, Weigang; Hu, Songmei; Chen, Liang; Hu, Yaowu; Richards, Michael P.

    2016-06-01

    The mausoleum complex of the First Emperor of China, Qin Shi Huang (259-210 BC), is one of the most famous and important archaeological sites in China, yet questions remain as to how it was constructed and by whom. Here we present isotopic results of individuals from the Liyi (n = 146) and Shanren sites (n = 14), both associated with the mausoleum complex. Those buried at Liyi represent the local workers/inhabitants of the Qin population, and the δ13C (-8.7 ± 1.5%) and δ15N (10.3 ± 0.7%) values indicate that they consumed predominately millet and/or domestic animals fed millet. In contrast, the Shanren individuals were prisoners forced to construct the mausoleum (found buried haphazardly in a mass grave and some in iron leg shackles), and their δ13C (-15.4 ± 2.9%) and δ15N (8.0 ± 0.6%) results indicate a more mixed C3/C4 diet, with possibly less domestic animals and more wild game protein consumed. This pattern of decreased millet consumption is also characteristic of archaeological sites from southern China, and possible evidence the Shanren prisoners originated from this region (possibly the ancient Chu state located in modern day Hubei Province and parts of Hunan and Anhui Provinces). Further, this finding is in agreement with historical sources and is supported by previous ancient DNA evidence that the mausoleum workers had diverse origins, with many genetically related to southern Chinese groups.

  10. Plasticity in animal personality traits: does prior experience alter the degree of boldness?

    PubMed

    Frost, Ashley J; Winrow-Giffen, Alexandria; Ashley, Paul J; Sneddon, Lynne U

    2007-02-07

    Theoreticians predict that animal 'personality' traits may be maladaptive if fixed throughout different contexts, so the present study aimed to test whether these traits are fixed or plastic. Rainbow trout (Onchorhyncus mykiss) were given emboldening or negative experiences in the forms of watching bold or shy individuals responding to novelty or winning or losing fights to examine whether prior experience affected boldness. Bold individuals that lost fights or watched shy demonstrators became more shy by increasing their latency to approach a novel object, whereas shy observers that watched bold demonstrators remained cautious and did not modify their responses to novelty. Shy winners became bolder and decreased their latency to approach a novel object, but shy losers also displayed this shift. In comparison, control groups showed no change in behaviour. Bold fishes given negative experiences reduced their boldness which may be an adaptive response; however, shy fishes may base their strategic decisions upon self-assessment of their relative competitive ability and increase their boldness in situations where getting to resources more quickly ensures they outcompete better competitors.

  11. Ras inhibitors display an anti-metastatic effect by downregulation of lysyl oxidase through inhibition of the Ras-PI3K-Akt-HIF-1α pathway.

    PubMed

    Yoshikawa, Yoko; Takano, Osamu; Kato, Ichiro; Takahashi, Yoshihisa; Shima, Fumi; Kataoka, Tohru

    2017-12-01

    Metastasis stands as the major obstacle for the survival from cancers. Nonetheless most existing anti-cancer drugs inhibit only cell proliferation, and discovery of agents having both anti-proliferative and anti-metastatic properties would be more beneficial. We previously reported the discovery of small-molecule Ras inhibitors, represented by Kobe0065, that displayed anti-proliferative activity on xenografts of human colorectal cancer (CRC) cell line SW480 carrying the K-ras G12V gene. Here we show that treatment of cancer cells carrying the activated ras genes with Kobe0065 or a siRNA targeting Ras downregulates the expression of lysyl oxidase (LOX), which has been implicated in metastasis. LOX expression is enhanced by co-expression of Ras G12V through activation of phosphatidylinositol 3-kinase (PI3K)/Akt and concomitant accumulation of hypoxia-inducible factor (HIF)-1α. Furthermore, Kobe0065 effectively inhibits not only migration and invasion of cancer cells carrying the activated ras genes but also lung metastasis of human CRC cell line SW620 carrying the K-ras G12V gene. Collectively, these results indicate that Kobe0065 prevents metastasis through inhibition of the Ras-PI3K-Akt-HIF-1α-LOX signaling and suggest that Ras inhibitors in general might exhibit both anti-proliferative and anti-metastatic properties toward cancer cells carrying the activated ras genes. Copyright © 2017 Elsevier B.V. All rights reserved.

  12. Differentiating social phobia from shyness.

    PubMed

    Heiser, Nancy A; Turner, Samuel M; Beidel, Deborah C; Roberson-Nay, Roxann

    2009-05-01

    To clarify the relationship between social phobia and shyness, this study examined the characteristics of highly shy persons with social phobia, highly shy persons without social phobia, and non-shy persons. Those with social phobia reported more symptomatology, more functional impairment, and a lower quality of life than those without social phobia. About one-third of the highly shy without social phobia reported no social fears, highlighting heterogeneity of the shy. The social phobia group reported similar levels of anxiety as the shy without social phobia during analogue conversation tasks, but they reported more anxiety during a speech task. The social phobia group performed less effectively across tasks than those without social phobia. All groups' perceptions of anxiety and effectiveness during behavioral tasks were consistent with ratings of independent observers. None of the groups differed on psychophysiological measures. Results are discussed in the context of theoretical models of social phobia.

  13. [The significance of a large number of health insurance funds and fusions for health services research with statutory health insurance data in Germany - experiences of the lidA study].

    PubMed

    March, S; Powietzka, J; Stallmann, C; Swart, E

    2015-02-01

    Since 1970 the health insurance system in Germany has shrunk by more than 90% to 132 statutory health insurance funds (SHI) at present. For studies using data from different SHI, this development means a reduction of contacts and a higher workload when requesting data. The latter is due to the fact that fusions bind resources in the health insurance funds. In order to avoid selection in studies among the insured, all SHI must be contacted. Additionally, 15 controlling institutions on the state and national level have to agree as determined in § 75 of the German Social Code number 10. The lidA study - a German cohort study on work, age and health intends to link primary and secondary data from all SHI of those insured who have given their agreement for participation. Since the beginning of the study in 2009 the number of SHI has been reduced by 70. Of the 6 585 interviews in 2011 approximately half of the interviewees agreed in written form that their individual health insurance data can be linked. This portion of the insured is dispersed among 95 SHI. At this point, 11 contracts with SHI are realised (approximately 50% of the insured) and 8 data controlling authorities have been contacted. The problems involved in the fusion of SHI and its meaning for research are explained in this article. The fusion of SHI makes sense for the long term. It will lead to a reduction of contacts and contracts that researchers have to establish in order to analyse the data. Therefore, this article also discusses the alternative of creating a meta-data set of all the data from the different SHI combined. © Georg Thieme Verlag KG Stuttgart · New York.

  14. Social health insurance and labor market outcomes: evidence from central and eastern Europe, and central Asia.

    PubMed

    Wagstaff, Adam; Moreno-Serra, Rodrigo

    2009-01-01

    The implications of social health insurance (SHI) for labor markets have featured prominently in recent debates over the merits of SHI and general revenue financing. It has been argued that by raising the nonwage component of labor costs, SHI reduces firms' demand for labor, lowers employment levels and net wages, and encourages self-employment and informal working arrangements. At the national level, SHI has been claimed to reduce a country's competitiveness in international markets and to discourage foreign direct investment (FDI). The transition from general revenue finance to SHI that occurred during the 1990s in many of the central and eastern European and central Asian countries provides a unique opportunity to investigate empirically these claims. We employ regression-based generalizations of difference-in-differences (DID) and instrumental variables (IV) on country-level panel data from 28 countries for the period 1990-2004. We find that, controlling for gross domestic product (GDP) per capita, SHI increases (gross) wages by 20%, reduces employment (as a share of the population) by 10%, and increases self-employment by 17%. However, we find no significant effects of SHI on unemployment (registered or self-reported), agricultural employment, a widely used measure of the size of the informal economy, or FDI. We do not claim that our results imply that SHI adoption everywhere must necessarily reduce employment and increase self-employment. Nonetheless, our results ought to serve as a warning to those contemplating shifting the financing of health care from general revenues to a SHI system.

  15. Stone heterogeneity index as the standard deviation of Hounsfield units: A novel predictor for shock-wave lithotripsy outcomes in ureter calculi.

    PubMed

    Lee, Joo Yong; Kim, Jae Heon; Kang, Dong Hyuk; Chung, Doo Yong; Lee, Dae Hun; Do Jung, Hae; Kwon, Jong Kyou; Cho, Kang Su

    2016-04-01

    We investigated whether stone heterogeneity index (SHI), which a proxy of such variations, was defined as the standard deviation of a Hounsfield unit (HU) on non-contrast computed tomography (NCCT), can be a novel predictor for shock-wave lithotripsy (SWL) outcomes in patients with ureteral stones. Medical records were obtained from the consecutive database of 1,519 patients who underwent the first session of SWL for urinary stones between 2005 and 2013. Ultimately, 604 patients with radiopaque ureteral stones were eligible for this study. Stone related variables including stone size, mean stone density (MSD), skin-to-stone distance, and SHI were obtained on NCCT. Patients were classified into the low and high SHI groups using mean SHI and compared. One-session success rate in the high SHI group was better than in the low SHI group (74.3% vs. 63.9%, P = 0.008). Multivariate logistic regression analyses revealed that smaller stone size (OR 0.889, 95% CI: 0.841-0.937, P < 0.001), lower MSD (OR 0.995, 95% CI: 0.994-0.996, P < 0.001), and higher SHI (OR 1.011, 95% CI: 1.008-1.014, P < 0.001) were independent predictors of one-session success. The radiologic heterogeneity of urinary stones or SHI was an independent predictor for SWL success in patients with ureteral calculi and a useful clinical parameter for stone fragility.

  16. Swift heavy ion irradiation effects on structural, optical properties and ac conductivity of polypyrrole nanofibers

    NASA Astrophysics Data System (ADS)

    Hazarika, J.; Kumar, A.

    2016-12-01

    Polypyrrole (PPy) nanofibers have been synthesized by interfacial polymerization method and irradiated with 160 MeV Ni12+ ions under vacuum with fluences in the range of 1010-1012 ions/cm2. High-resolution transmission electron microscopy results show that upon swift heavy ion (SHI) irradiation the PPy nanofibers become denser. The crystallinity of PPy nanofibers increases upon SHI irradiation, while their d-spacing decreases. Upon SHI irradiation, the polaron absorption band gets red-shifted indicating reduction in the optical band gap energy of the irradiated PPy nanofibers. The indirect optical band gap energy is decreased as compared to corresponding direct optical band gap energy. The number of carbon atoms per conjugation length (N) and carbon atoms per cluster (M) of the SHI-irradiated PPy nanofibers increase with increasing the irradiation fluence. Fourier transform infrared spectra reveal the enhancement in intensity of some characteristic vibration bands upon SHI irradiation. The thermal stability of the PPy nanofibers is enhanced on SHI irradiation. The charge carriers in both pristine and irradiated PPy nanofibers follow the correlated barrier hopping mechanism. Scaling of ac conductivity reveals that the conduction mechanism is independent of the SHI irradiation fluence.

  17. The Silent Prison of Shyness.

    DTIC Science & Technology

    1977-11-01

    interventions to help the shy overcome their daily difficulties, it might be well to consider how long we should support individual therapies which, even if...Haw thorne Do you consider yourself to be a shy person? Have you always been shy? How did you reach that conclusion and what evidence could convince...you otherwise? Can you say that you like being shy? What consequences does shyness have for you? And what) if anything, canI be done to alter the

  18. Differentiating Social Phobia from Shyness

    PubMed Central

    Heiser, Nancy A.; Turner, Samuel M.; Beidel, Deborah C.; Roberson-Nay, Roxann

    2009-01-01

    To clarify the relationship between social phobia and shyness, this study examined the characteristics of highly shy persons with social phobia, highly shy persons without social phobia, and non-shy persons. Those with social phobia reported more symptomatology, more functional impairment, and a lower quality of life than those without social phobia. About one-third of the highly shy without social phobia reported no social fears, highlighting heterogeneity of the shy. The social phobia group reported similar levels of anxiety as the shy without social phobia during analogue conversation tasks, but they reported more anxiety during a speech task. The social phobia group performed less effectively across tasks than those without social phobia. All groups’ perceptions of anxiety and effectiveness during behavioral tasks were consistent with ratings of independent observers. None of the groups differed on psychophysiological measures. Results are discussed in the context of theoretical models of social phobia. PMID:19028075

  19. From Kobe Bryant to Campus Rape

    ERIC Educational Resources Information Center

    Malveaux, Julianne

    2004-01-01

    Even though laws have been passed to protect young women--who are most at risk for rape--from sexual assault on campus, many young men think they can rape without consequence. Thus, the Campus Security Act of 1990 (now known as the Jerome Clery Act), which requires campuses to report serious crimes on campus, and the Campus Sexual Assault Victim's…

  20. Social health insurance in a developing country: the case of the Philippines.

    PubMed

    Obermann, Konrad; Jowett, Matthew R; Alcantara, Maria Ofelia O; Banzon, Eduardo P; Bodart, Claude

    2006-06-01

    Very little is known about the Philippine health care system, and in particular its experience with social health insurance (SHI). Having initiated an SHI programme 35 years ago, the Philippines hold many lessons for the development of such schemes in other low and middle-income countries. We analyse the challenges currently facing PhilHealth, the national health insurer. PhilHealth was formed in 1995 as a successor to the Medicare programme and was given a mandate to achieve universal coverage by 2010. To date, PhilHealth has been quite successful in some areas (e.g. enrollment), but lags behind in others (e.g. quality and price control). We conclude that SHI in the Philippines has been a success story so far and provides lessons for countries in a similar situation. For example: (i) SHI is based on value decisions and the clear statement of societal goals can give guidance in the technical execution, (ii) SHI is a financing institution and needs to be treated accordingly, (iii) SHI can be implemented independently of the current economic situation and might actually contribute to economic development, (iv) community-based health care financing schemes should be merged with the national SHI in the long run, and (v) there is a strong need to push for high quality care and improved physical access. No clear suggestions can be given with respect to the benefit catalogue and the balance between economies of scale and decentralisation. Although riddled with many inadequacies, PhilHealth was set up as a strong and largely politically independent institution for the development of SHI. SHI can act as a stabilizing institution in a politically and economically volatile environment.

  1. "He is just a little shy like me": screening for autism in a young child.

    PubMed

    Weissman, Laura; Sices, Laura; Augustyn, Marilyn

    2010-10-01

    accountant and father as a physicist in a commercial laboratory. Both have graduate degrees and are trilingual. The parents are conflicted in their interpretation of Jacob's behavior. His father is concerned that he is autistic and his mother feels that "he is just a little shy like me." His physical examination is normal. He is somewhat inhibited and anxious but will sit still on the examination table and alone during the examination. You update his immunizations and then struggle with where to head next.

  2. Stone heterogeneity index as the standard deviation of Hounsfield units: A novel predictor for shock-wave lithotripsy outcomes in ureter calculi

    PubMed Central

    Lee, Joo Yong; Kim, Jae Heon; Kang, Dong Hyuk; Chung, Doo Yong; Lee, Dae Hun; Do Jung, Hae; Kwon, Jong Kyou; Cho, Kang Su

    2016-01-01

    We investigated whether stone heterogeneity index (SHI), which a proxy of such variations, was defined as the standard deviation of a Hounsfield unit (HU) on non-contrast computed tomography (NCCT), can be a novel predictor for shock-wave lithotripsy (SWL) outcomes in patients with ureteral stones. Medical records were obtained from the consecutive database of 1,519 patients who underwent the first session of SWL for urinary stones between 2005 and 2013. Ultimately, 604 patients with radiopaque ureteral stones were eligible for this study. Stone related variables including stone size, mean stone density (MSD), skin-to-stone distance, and SHI were obtained on NCCT. Patients were classified into the low and high SHI groups using mean SHI and compared. One-session success rate in the high SHI group was better than in the low SHI group (74.3% vs. 63.9%, P = 0.008). Multivariate logistic regression analyses revealed that smaller stone size (OR 0.889, 95% CI: 0.841–0.937, P < 0.001), lower MSD (OR 0.995, 95% CI: 0.994–0.996, P < 0.001), and higher SHI (OR 1.011, 95% CI: 1.008–1.014, P < 0.001) were independent predictors of one-session success. The radiologic heterogeneity of urinary stones or SHI was an independent predictor for SWL success in patients with ureteral calculi and a useful clinical parameter for stone fragility. PMID:27035621

  3. Eliciting preferences for social health insurance in Ethiopia: a discrete choice experiment.

    PubMed

    Obse, Amarech; Ryan, Mandy; Heidenreich, Sebastian; Normand, Charles; Hailemariam, Damen

    2016-12-01

    As low-income countries are initiating health insurance schemes, Ethiopia is also planning to move away from out-of-pocket private payments to health insurance. The success of such a policy depends on understanding and predicting preferences of potential enrolees. This is because a scarce health care budget forces providers and consumers to make trade-offs between potential benefits within a health insurance. An assessment of preferences of potential enrolees can therefore add important information to optimal resource allocation in the design of health insurance. We used a discrete choice experiment to elicit preferences for social health insurance (SHI) among formal sector employees in Ethiopia. Respondents were presented with 18 binary hypothetical choices of SHI. Each insurance package was described by eight policy relevant attributes: premium, enrolment, exclusions, providers and coverage of inpatient services, outpatient services, drugs and tests. A mixed logit model was estimated to determine respondents' willingness to pay (WTP) for the different health insurance attributes. We also predicted probabilities of uptake for alternative SHI scenarios. Health insurance packages with 'no exclusions', 'public and private' providers, low rate of premium and full coverage of tests and drugs were highly valued and had greatest impact on the choices . Other things being equal, respondents were willing to contribute 1.52% (95% confidence interval (CI): 0.71, 2.32) of their salary to a SHI package with no service exclusions having public and private service providers. This is substantially lower than the proposed 3% premium in the draft SHI strategy. For the typical SHI package proposed by the SHI strategy at the time, the uptake probability was predicted to be 29% (95% CI: 0.25, 0.33). The low uptake probability and WTP for the proposed SHI package suggests considering preferences of the potential enrolees' in revisions of the draft SHI strategy for introduction of

  4. Willingness to Pay for Social Health Insurance in Central Vietnam.

    PubMed

    Nguyen, Lan Hoang; Hoang, Anh Thuan Duc

    2017-01-01

    A social health insurance (SHI) program was implemented in Vietnam in 1992. Participation is compulsory for some groups, such as formal-sector workers and voluntary for other groups. In 2013, 68% of the total population was covered by SHI, with most enrollees from compulsory groups. Enrollment has remained low among persons whose enrollment is voluntary. As a result, households face financial risk due to high out-of-pocket payments for health care. The goal of this study is to identify willingness to pay (WTP) for the SHI scheme among persons whose enrollment is voluntary and to examine factors that influence their choice. Three hundred thirty-one uninsured persons from three districts and one city of Thua Thien Hue province were interviewed face to face using a structured questionnaire. Contingent valuation technique was used to assess the WTP among the study participants. Each individual was asked to choose the maximum premium they were willing to pay for a health insurance card per year with three copayment levels of 0, 10, and 20%. Seven premium levels were offered ranging from 0 to 900,000 Vietnamese Dong (VND) (42.12 USD). The mean WTP of respondents for each scenario was estimated. Multiple linear regression analysis was used to identify factors influencing WTP for SHI. The survey found that 73.1, 72.2, and 71.6%, respectively, for each copayment level, of the respondents would agree to participate in the SHI scheme and are willing to pay an annual premium of 578,926 VND (27.1 USD); 473,222 VND (22.1 USD); and 401,266 VND (18.8 USD) at the copayment levels of 0, 10, and 20%, respectively. The WTP for SHI is influenced by knowledge of SHI at all copayment levels ( p value < 0.05). The more knowledge about SHI individuals have, the higher the WTP amount. Chronic disease was related to WTP only at a copayment level of 20% ( p  = 0.049). Enhanced awareness of the benefits of SHI among the population should contribute to expanding SHI coverage in Vietnam.

  5. Comments on the status of Xiphidiopsis quadrinotata Bey-Bienko, 1971 and related species with one new genus and species (Orthoptera: Tettigoniidae: Meconematinae).

    PubMed

    Shi, Fuming; Bian, Xun; Zhou, Zhijun

    2016-04-21

    Based on the collections of the Museum of Hebei University, the paper comments Xiphidiopsis quadrinotata Bey-Bienko, 1971 status and reinstates Xizicus (Axizicus) xizangensis Jiao & Shi, 2013 as a valid species. Meanwhile, Alloteratura (Meconemopsis) Karny, 1924 is redefined and one new genus of Meconematinae, Nigrimacula Shi, Bian & Zhou gen. nov., mainly distributed in South China, is erected. The new genus includes three previously known species: Xiphidiopsis quadrinotata Bey-Bienko, 1971, Xizicus (Axizicus) xizangensis Jiao & Shi, 2013 and Meconemopsis paraquadrinotata Wang, Liu & Li, 2015 and one new species, Nigrimacula binotata Shi, Bian & Zhou sp. nov. The male of Xiphidiopsis quadrinotata Bey-Bienko, 1971 and female of Xizicus (Axizicus) xizangensis Jiao & Shi, 2013 are described for the first time. A key to the species based on the morphology and a distribution map are included.

  6. The Validation and Reliability of the Chinese Version of the Speech Handicap Index for Patients With Oral and Oropharyngeal Cancer.

    PubMed

    Li, Tianzhu; Ma, Lian; Mao, Chi

    2016-03-01

    The purpose of this study was to investigate the validity and reliability of the translated Chinese version of the Speech Handicap Index (SHI) questionnaire for Chinese-speaking patients with oral and oropharyngeal cancer. The original English version of the SHI was translated into Chinese. Forty-two consecutive patients with oral and oropharyngeal cancer were included in the study. All subjects were asked to complete the Chinese version of the SHI and the University of Washington Quality of Life Questionnaire (UWQOL V.04). Fifteen patients were randomly retested on both questionnaires 2 weeks later. The internal consistency, test-retest reliability, construct validity, and group validity of the Chinese version of the SHI were tested using Cronbach α, Spearman correlation coefficient (r), and Mann-Whitney U tests. Descriptive and bivariate statistics were computed, and the P value was set to 0.05. The Cronbach α for the total SHI, the speech domain, and the psychosocial domain were 0.96, 0.90, and 0.92, respectively. The test-retest reliability scores for the total SHI, the speech domain, the psychosocial domain, and the overall question were 0.94, 0.97, 0.90, and 0.83, respectively. To measure construct validity, Spearman correlation coefficients between different items of the SHI and the UWQOL were all >0.4, which signified a moderate to significant correlation. There were significant differences between patient groups when divided by age, clinical stage, educational level, radiotherapy, and reconstruction, on all or on parts of the various SHI domains. The Chinese version of the SHI is a valid and reliable tool for the speech assessment of patients with oral and oropharyngeal cancer. Copyright © 2016 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  7. Three new species of the genus Xiphidiopsis Redtenbacher, 1891 (Orthoptera: Tettigoniidae: Meconematinae) in China.

    PubMed

    Han, Li; Di, Juan-Xia; Chang, Yan-Lin; Shi, Fu-Ming

    2015-09-17

    The article reported three new species of the genus Xiphidiopsis Redtenbacher, 1891 in China: Xiphidiopsis (Xiphidiopsis) minorincisus Han, Chang & Shi sp. nov., Xiphidiopsis (Xiphidiopsis) protensus Han, Chang & Shi sp. nov. and Xiphidiopsis (Xiphidiopsis) anisolobulus Han, Di & Shi sp. nov. The type material is deposited in the Museum of Hebei University, Baoding, P. R. China.

  8. Shyness and Adaptation to School in a Chinese Community

    ERIC Educational Resources Information Center

    Feng, Xin; Harkness, Sara; Super, Charles M.; Jia, Rongfang

    2014-01-01

    This study examined the process of adjustment in shy and nonshy children during the transition to school in a Chinese community. Children (35 shy and 19 nonshy) were assessed three times before and after they entered the first grade. Shy and nonshy children's interactions with peers and teachers, perceived peer acceptance, and anxious behaviour…

  9. Smart home in a box: usability study for a large scale self-installation of smart home technologies.

    PubMed

    Hu, Yang; Tilke, Dominique; Adams, Taylor; Crandall, Aaron S; Cook, Diane J; Schmitter-Edgecombe, Maureen

    2016-07-01

    This study evaluates the ability of users to self-install a smart home in a box (SHiB) intended for use by a senior population. SHiB is a ubiquitous system, developed by the Washington State University Center for Advanced Studies in Adaptive Systems (CASAS). Participants involved in this study are from the greater Palouse region of Washington State, and there are 13 participants in the study with an average age of 69.23. The SHiB package, which included several different types of components to collect and transmit sensor data, was given to participants to self-install. After installation of the SHiB, the participants were visited by researchers for a check of the installation. The researchers evaluated how well the sensors were installed and asked the resident questions about the installation process to help improve the SHiB design. The results indicate strengths and weaknesses of the SHiB design. Indoor motion tracking sensors are installed with high success rate, low installation success rate was found for door sensors and setting up the Internet server.

  10. Smart home in a box: usability study for a large scale self-installation of smart home technologies

    PubMed Central

    Hu, Yang; Tilke, Dominique; Adams, Taylor; Crandall, Aaron S.; Schmitter-Edgecombe, Maureen

    2017-01-01

    This study evaluates the ability of users to self-install a smart home in a box (SHiB) intended for use by a senior population. SHiB is a ubiquitous system, developed by the Washington State University Center for Advanced Studies in Adaptive Systems (CASAS). Participants involved in this study are from the greater Palouse region of Washington State, and there are 13 participants in the study with an average age of 69.23. The SHiB package, which included several different types of components to collect and transmit sensor data, was given to participants to self-install. After installation of the SHiB, the participants were visited by researchers for a check of the installation. The researchers evaluated how well the sensors were installed and asked the resident questions about the installation process to help improve the SHiB design. The results indicate strengths and weaknesses of the SHiB design. Indoor motion tracking sensors are installed with high success rate, low installation success rate was found for door sensors and setting up the Internet server. PMID:28936390

  11. Applying dam height-storage curve to geomorphic features analysis within virtual geographic environment: a case study of the Hong-Shi-Mao watershed

    NASA Astrophysics Data System (ADS)

    Wang, Daojun; Gong, Jianhua; Ma, Ainai; Li, Wenhang; Wang, Xijun

    2005-10-01

    There are generally two kinds of approaches to studying geomorphic features in terms of the quantification level and difference of major considerations. One is the earlier qualitative characterization, and the other is the 2-dimension measurement that includes section pattern and projection pattern. With the development of geo-information technology, especially the 3-D geo-visualization and virtual geographic environments (VGE), 3-dimension measurement and dynamic interactive between users and geo-data/geo-graphics can be developed to understand geomorphic features deeply, and to benefit to the effective applications of such features for geographic projects like dam construction. Storage-elevation curve is very useful for site selection of projects and flood dispatching in water conservancy region, but it is just a tool querying one value from the other one. In fact, storage-elevation curve can represent comprehensively the geomorphic features including vertical section, cross section of the stream and the landform nearby. In this paper, we use quadratic regression equation shaped like y = ax2 + bx + c and the DEM data of Hong-Shi-Mao watershed, Zi Chang County, ShaanXi Province, China to find out the relationship between the coefficients of the equation and the geomorphic features based on VGE platform. It's exciting that the coefficient "a" appear to be correlative strongly with the stream scale, and the coefficient "b" may give an index to the valley shape. In the end, we use a sub-basin named Hao-Jia-Gou of the watershed as an application. The result of correlative research about quadratic regression equation and geomorphic features can save computing and improve the efficiency in silt dam systems planning.

  12. Analysis of Leigh syndrome mutations in the yeast SURF1 homolog reveals a new member of the cytochrome oxidase assembly factor family.

    PubMed

    Bestwick, Megan; Jeong, Mi-Young; Khalimonchuk, Oleh; Kim, Hyung; Winge, Dennis R

    2010-09-01

    Three missense SURF1 mutations identified in patients with Leigh syndrome (LS) were evaluated in the yeast homolog Shy1 protein. Introduction of two of the Leigh mutations, F(249)T and Y(344)D, in Shy1 failed to significantly attenuate the function of Shy1 in cytochrome c oxidase (CcO) biogenesis as seen with the human mutations. In contrast, a G(137)E substitution in Shy1 results in a nonfunctional protein conferring a CcO deficiency. The G(137)E Shy1 mutant phenocopied shy1Delta cells in impaired Cox1 hemylation and low mitochondrial copper. A genetic screen for allele-specific suppressors of the G(137)E Shy1 mutant revealed Coa2, Cox10, and a novel factor designated Coa4. Coa2 and Cox10 are previously characterized CcO assembly factors. Coa4 is a twin CX(9)C motif mitochondrial protein localized in the intermembrane space and associated with the inner membrane. Cells lacking Coa4 are depressed in CcO activity but show no impairment in Cox1 maturation or formation of the Shy1-stabilized Cox1 assembly intermediate. To glean insights into the functional role of Coa4 in CcO biogenesis, an unbiased suppressor screen of coa4Delta cells was conducted. Respiratory function of coa4Delta cells was restored by the overexpression of CYC1 encoding cytochrome c. Cyc1 is known to be important at an ill-defined step in the assembly and/or stability of CcO. This new link to Coa4 may begin to further elucidate the role of Cyc1 in CcO biogenesis.

  13. Impacts of the type of social health insurance on health service utilisation and expenditures: implications for a unified system in China.

    PubMed

    Tan, Si Ying; Wu, Xun; Yang, Wei

    2018-05-08

    While moving towards unified social health insurance (SHI) is often a politically popular policy reform in countries where rapid expansion in health insurance coverage has given rise to the segmentation of SHI systems as different SHI schemes were rolled out to serve different populations, the potential impacts of reform on service utilisation and health costs have not been systematically studied. Using data from the Chinese Health and Retirement Longitudinal Study (CHARLS), we compared the mean costs incurred for both inpatient and outpatient care under different health insurance schemes, and the impact of different SHI schemes on treatment utilisation and health care costs using a two-part model. Our results show that Urban Employee Medical Insurance, which offers the most generous benefits, incurs the highest total costs prior to reimbursement when compared to other SHI schemes. Our analysis also shows that utilisation of SHI did not show significant reduction in out-of-pocket payments for outpatients. We argue that, unless effective measures are introduced to deal with perverse provider payment incentives, the move towards a unified system with more generous benefits may usher in a new wave of cost escalation for health care systems in China.

  14. Clinical Severity Classification using Automated Conjunctival Hyperemia Analysis Software in Patients with Superior Limbic Keratoconjunctivitis.

    PubMed

    Kurita, Junki; Shoji, Jun; Inada, Noriko; Yoneda, Tsuyoshi; Sumi, Tamaki; Kobayashi, Masahiko; Hoshikawa, Yasuhiro; Fukushima, Atsuki; Yamagami, Satoru

    2018-06-01

    Digitization of clinical observation is necessary for assessing the severity of superior limbic keratoconjunctivitis (SLK). This study aimed to use a novel quantitative marker to examine hyperemia in patients with SLK. We included six eyes of six patients with both dry eye disease and SLK (SLK group) and eight eyes of eight patients with Sjögren syndrome (SS group). We simultaneously obtained the objective finding scores by using slit-lamp examination and calculated the superior hyperemia index (SHI) with an automated conjunctival hyperemia analysis software by using photographs of the anterior segment. Three objective finding scores, including papillary formation of the superior palpebral conjunctiva, superior limbal hyperemia and swelling, and superior corneal epitheliopathy, were determined. The SHI was calculated as the superior/temporal ratio of bulbar conjunctival hyperemia by using the software. Fisher's exact test was used to compare a high SHI (≥1.07) ratio between the SLK and SS groups. P-Values < 0.05 were considered statistically significant. The SHI (mean ± standard deviation) in the SLK and SS groups was 1.19 ± 0.50 and 0.69 ± 0.24, respectively. The number of patients with a high SHI (≥1.07) was significantly higher in the SLK group than in the SS group (p < 0.05). The sensitivity and specificity of the SHI in the differential diagnosis between SS and SLK were 66.7% and 87.5%, respectively. An analysis of the association between the objective finding scores and SHI showed that the SHI had a tendency to indicate the severity of superior limbal hyperemia and swelling score in the SLK group. The SHI calculated using the automated conjunctival hyperemia analysis software could successfully quantify superior bulbar conjunctival hyperemia and may be a useful tool for the differential diagnosis between SS and SLK and for the quantitative follow-up of patients with SLK.

  15. Simulated Hail Ice Mechanical Properties and Failure Mechanism at Quasi-Static Strain Rates

    NASA Astrophysics Data System (ADS)

    Swift, Jonathan M.

    Hail is a significant threat to aircraft both on the ground and in the air. Aeronautical engineers are interested in better understanding the properties of hail to improve the safety of new aircraft. However, the failure mechanism and mechanical properties of hail, as opposed to clear ice, are not well understood. A literature review identifies basic mechanical properties of ice and a failure mechanism based upon the state of stress within an ice sphere is proposed. To better understand the properties of Simulated Hail Ice (SHI), several tests were conducted using both clear and cotton fiber reinforced ice. Pictures were taken to show the internal crystal structure of SHI. SHI crush tests were conducted to identify the overall force-displacement trends at various quasi-static strain rates. High speed photography was also used to visually track the failure mechanism of spherical SHI. Compression tests were done to measure the compression strength of SHI and results were compared to literature data. Fracture toughness tests were conducted to identify the crack resistance of SHI. Results from testing clear ice samples were successfully compared to previously published literature data to instill confidence in the testing methods. The methods were subsequently used to test and characterize the cotton fiber reinforced ice.

  16. Discrimination in waiting times by insurance type and financial soundness of German acute care hospitals.

    PubMed

    Schwierz, Christoph; Wübker, Achim; Wübker, Ansgar; Kuchinke, Björn A

    2011-10-01

    This paper shows that patients with private health insurance (PHI) are being offered significantly shorter waiting times than patients with statutory health insurance (SHI) in German acute hospital care. This behavior may be driven by the higher expected profitability of PHI relative to SHI holders. Further, we find that hospitals offering private insurees shorter waiting times when compared with SHI holders have a significantly better financial performance than those abstaining from or with less discrimination.

  17. Thermal annealing and SHI irradiation induced modifications in sandwiched structured Carbon-gold-Carbon (a-C/Au/a-C) nanocomposite thin film

    NASA Astrophysics Data System (ADS)

    Singh, S. K.; Singhal, R.

    2017-09-01

    In the present work, we study the annealing and swift heavy ion (SHI) beam induced modifications in the optical and structural properties of sandwiched structured Carbon-gold-Carbon (a-C/Au/a-C) nanocomposite (NCs) thin films. The NCs thin films were synthesized by electron-beam evaporation technique at room temperature with ∼30 nm thickness for both carbon layer and ∼6 nm for gold layer. Gold-carbon NCs thin films were annealed in the presence of argon at a temperature of 500 °C, 600 °C and 750 °C. The NCs thin films were also irradiated with 90 MeV Ni ions beam with different ion fluences in the range from 3 × 1012, 6 × 1012 and 1 × 1013 ions/cm2. Surface plasmon resonance (SPR) of Au nanoparticles are not observed in the pristine film but, after annealing at temperature of 600 °C and 750 °C, it was clearly seen at ∼534 nm as confirmed by UV-visible absorption spectroscopy. 90 MeV Ni irradiated thin film at the fluence of 1 × 1013 ions/cm2 also show strong absorption band at ∼534 nm. The growth and size of Au nanoparticle for pristine and 90 MeV Ni ion irradiated thin film with fluence of 1 × 1013 ions/cm2, were estimated by Transmission electron microscopy (TEM) images with the bi-model distribution. The size of the gold nanoparticle (NPs) was found to be ∼4.5 nm for the pristine film and ∼5.4 nm for the irradiated film at a fluence of 1 × 1013 ions/cm2. The thickness and metal atomic fraction in carbon matrix were estimated by Rutherford backscattering spectroscopy (RBS). The effect of annealing as well as heavy ion irradiation on D and G band of carbon matrix were studied by Raman spectroscopy.

  18. Social health insurance coverage and financial protection among rural-to-urban internal migrants in China: evidence from a nationally representative cross-sectional study

    PubMed Central

    Chen, Wen; Zhang, Qi; Renzaho, Andre M N; Zhou, Fangjing; Zhang, Hui; Ling, Li

    2017-01-01

    Introduction Migrants are a vulnerable population and could experience various challenges and barriers to accessing health insurance. Health insurance coverage protects migrants from financial loss related to illness and death. We assessed social health insurance (SHI) coverage and its financial protection effect among rural-to-urban internal migrants (IMs) in China. Methods Data from the ‘2014 National Internal Migrant Dynamic Monitoring Survey’ were used. We categorised 170 904 rural-to-urban IMs according to their SHI status, namely uninsured by SHI, insured by the rural SHI scheme (new rural cooperative medical scheme (NCMS)) or the urban SHI schemes (urban employee-based basic medical insurance (UEBMI)/urban resident-based basic medical insurance (URBMI)), and doubly insured (enrolled in both rural and urban schemes). Financial protection was defined as ‘the percentage of out-of-pocket (OOP) payments for the latest inpatient service during the past 12 months in the total household expenditure’. Results The uninsured rate of SHI and the NCMS, UEBMI/URBMI and double insurance coverage in rural-to-urban IMs was 17.3% (95% CI 16.9% to 17.7%), 66.6% (66.0% to 67.1%), 22.6% (22.2% to 23.0%) and 5.5% (5.3% to 5.7%), respectively. On average, financial protection indicator among uninsured, only NCMS insured, only URBMI/UEBMI insured and doubly insured participants was 13.3%, 9.2%, 6.2% and 5.8%, respectively (p=0.004). After controlling for confounding factors and adjusting the protection effect of private health insurance, compared with no SHI, the UEBMI/URBMI, the NCMS and double insurance could reduce the average percentage share of OOP payments by 33.9% (95% CI 25.5% to 41.4%), 14.1% (6.6% to 20.9%) and 26.8% (11.0% to 39.7%), respectively. Conclusion Although rural-to-urban IMs face barriers to accessing SHI schemes, our findings confirm the positive financial protection effect of SHI. Improving availability and portability of health insurance would

  19. Extension of NHWAVE to Couple LAMMPS for Modeling Wave Interactions with Arctic Ice Floes

    DTIC Science & Technology

    2015-09-30

    Modelling, in press. Orzech, M., Shi, F., Veeramony, J., Bateman , S., Calantoni, J., and Kirby, J. T., 2015, “Incorporating floating surface...objects into a fully dispersive surface wave model”, Ocean Modelling, submitted. Bateman , S. Shi, F., Orzech, M., Veeramony, J., and Calantoni, J., 2014...Orzech, M., Shi, F., Calantoni, J., Bateman , S., and Veeramony, J., “Small-scale modeling of waves and floes in the Marginal Ice Zone”, 2014 Fall Meeting of the American Geophysical Union.

  20. Notes on the genus Conanalus Tinkham, 1943 (Orthoptera: Tettigoniidae: Conocephalinae) with one new species from Yunnan, China.

    PubMed

    Du, Bao-Jie; Song, Qiong; Shi, Fu-Ming

    2015-06-05

    The paper describes one new species, i.e. Conanalus bilobus sp. nov., and provides additional information on Conanalus brevicaudus Shi, Mao & Ou, 2008 (including female description for the first time), and Conanalus robustus Shi, Mao & Ou, 2008 from Yunnan, as well as illustrations of important morphological characters of Conanalus axinus Shi, Wang & Fu, 2005. A distribution map of the species of Conanalus from Yunnan, China is presented. The type material is deposited in the Museum of Hebei University.

  1. QuEST: Robust Quantum Gadgets

    DTIC Science & Technology

    2013-02-28

    the size of the entangled states. Publications for 2011-12: S . T. Flammia , A. W. Harrow and J. Shi. “Local Embeddings of Quantum Codes” in...Publications (published) during reporting period: S . T. Flammia , A. W. Harrow and J. Shi. "Local Embeddings of Quantum Codes," in preparation, 2013. A. W...Publications: S . T. Flammia , A. W. Harrow and J. Shi. "Local Embeddings of Quantum Codes," in preparation, 2013. A. W. Harrow. "Testing Entanglement

  2. Stone heterogeneity index on single-energy noncontrast computed tomography can be a positive predictor of urinary stone composition

    PubMed Central

    Lee, Jong Soo; Cho, Kang Su; Lee, Seung Hwan; Yoon, Young Eun; Kang, Dong Hyuk; Jeong, Won Sik; Jung, Hae Do; Kwon, Jong Kyou

    2018-01-01

    The aim of this study was to investigate the correlation between stone composition and single-energy noncontrast computed tomography (NCCT) parameters, including stone heterogeneity index (SHI) and mean stone density (MSD), in patients with urinary calculi. We retrospectively reviewed medical records of 255 patients who underwent operations or procedures for urinary stones or had spontaneous stone passage between December 2014 and October 2015. Among these, 214 patients with urinary calculi who underwent NCCT and stone composition analyses were included in the study. Maximal stone length (MSL), mean stone density (MSD), and stone heterogeneity index (SHI) were determined on pretreatment NCCT. The mean MSD (454.68±177.80 HU) and SHI (115.82±96.31 HU) of uric acid stones were lower than those of all other types. Based on post hoc tests, MSD was lower for uric acid stones than for the other types (vs. CaOx: P<0.001; vs. infection stones: P<0.001). SHI was lower for uric acid stones than for the other types (vs. CaOx: P<0.001; vs. infection stones: P<0.001) Receiver operating characteristic curves of uric acid stones for MSD and SHI demonstrated that SHI (cut-off value: 140.4 HU) was superior to MSD (cut-off value: 572.3 HU) in predicting uric acid stones (P<0.001). PMID:29649219

  3. Leveraging multi-layer imager detector design to improve low-dose performance for megavoltage cone-beam computed tomography

    NASA Astrophysics Data System (ADS)

    Hu, Yue-Houng; Rottmann, Joerg; Fueglistaller, Rony; Myronakis, Marios; Wang, Adam; Huber, Pascal; Shedlock, Daniel; Morf, Daniel; Baturin, Paul; Star-Lack, Josh; Berbeco, Ross

    2018-02-01

    While megavoltage cone-beam computed tomography (CBCT) using an electronic portal imaging device (EPID) provides many advantages over kilovoltage (kV) CBCT, clinical adoption is limited by its high doses. Multi-layer imager (MLI) EPIDs increase DQE(0) while maintaining high resolution. However, even well-designed, high-performance MLIs suffer from increased electronic noise from each readout, degrading low-dose image quality. To improve low-dose performance, shift-and-bin addition (ShiBA) imaging is proposed, leveraging the unique architecture of the MLI. ShiBA combines hardware readout-binning and super-resolution concepts, reducing electronic noise while maintaining native image sampling. The imaging performance of full-resolution (FR); standard, aligned binned (BIN); and ShiBA images in terms of noise power spectrum (NPS), electronic NPS, modulation transfer function (MTF), and the ideal observer signal-to-noise ratio (SNR)—the detectability index (d‧)—are compared. The FR 4-layer readout of the prototype MLI exhibits an electronic NPS magnitude 6-times higher than a state-of-the-art single layer (SLI) EPID. Although the MLI is built on the same readout platform as the SLI, with each layer exhibiting equivalent electronic noise, the multi-stage readout of the MLI results in electronic noise 50% higher than simple summation. Electronic noise is mitigated in both BIN and ShiBA imaging, reducing its total by ~12 times. ShiBA further reduces the NPS, effectively upsampling the image, resulting in a multiplication by a sinc2 function. Normalized NPS show that neither ShiBA nor BIN otherwise affects image noise. The LSF shows that ShiBA removes the pixilation artifact of BIN images and mitigates the effect of detector shift, but does not quantifiably improve the MTF. ShiBA provides a pre-sampled representation of the images, mitigating phase dependence. Hardware binning strategies lower the quantum noise floor, with 2  ×  2 implementation reducing the

  4. Elucidating the association between the self-harm inventory and several borderline personality measures in an inpatient psychiatric sample.

    PubMed

    Sellbom, Martin; Sansone, Randy A; Songer, Douglas A

    2017-09-01

    The current study evaluated the utility of the self-harm inventory (SHI) as a proxy for and screening measure of borderline personality disorder (BPD) using several diagnostic and statistical manual of mental disorders (DSM)-based BPD measures as criteria. We used a sample of 145 psychiatric inpatients, who completed the SHI and a series of well-validated, DSM-based self-report measures of BPD. Using a series of latent trait and latent class analyses, we found that the SHI was substantially associated with a latent construct representing BPD, as well as differentiated latent classes of 'high' vs. 'low' BPD, with good accuracy. The SHI can serve as proxy for and a good screening measure for BPD, but future research needs to replicate these findings using structured interview-based measurement of BPD.

  5. Retraction Statement: "Overexpression of miR-708 and its targets in the childhood common precursor B-cell ALL" by Xue Li, MMed, Dong Li, PhD, Yong Zhuang, MMed, Qing Shi, BSc, Wei Wei, MMed, and Xiuli Ju, MD, PhD.

    PubMed

    2017-05-01

    The above article, published online 23 August 2013 in Pediatric Blood and Cancer, Volume 60, Issue 12, December 2013, Pages 2060-2067, has been retracted by agreement among the authors, the journal's Editor-in-Chief, Peter E. Newburger, M.D., and Wiley Periodicals, Inc. The decision to retract was agreed upon following notification that the paper substantially duplicates a prior study already published in Chinese https://www.ncbi.nlm.nih.gov/pubmed/23611221. The authors were not aware that publication in another language would constitute a duplicate publication and, upon being informed of this fact, have agreed to withdraw the paper from Pediatric Blood and Cancer. Reference Li X, Li D, Zhuang Y, Shi Q, Wei W and Ju X. Overexpression of miR-708 and its targets in the childhood common precursor B-cell ALL. Pediatr Blood Cancer. 2013; 60: 2060-2067. doi:10.1002/pbc.24583. © 2017 Wiley Periodicals, Inc.

  6. Elasticity of superhydrous phase B at the mantle temperature and pressure: Implications for 800-km discontinuity and water flow into lower mantle

    NASA Astrophysics Data System (ADS)

    Yang, D.; Wang, W.; Wu, Z.

    2017-12-01

    Plate subduction can transport the water to the Earth's interior by forming hydrous phases and water can exert important effects on global dynamics and many processes within the deep Earth. Superhydrous phase B (ShyB), as an important candidate for transporting water into the mantle transition zone and lower mantle, is stable up to 31 GPa and will decompose into bridgmanite, periclase and water at a depth of 800 km [Komabayashi and Omori, 2006]. The decomposition of ShyB may be related to the seismic discontinuity at the depth of 800 km in Western-Pacific Subduction Zones [Liu et al., 2016; Porritt and Yoshioka, 2016]. The detail discussions on this topic require the elasticity of ShyB at the P-T conditions of the transition zone and lower mantle. In this contribution, we obtained the thermal elasticity of ShyB using first-principles calculations. ShyB shows a very low velocity and density compared to the bridgmanite and periclase, the major minerals in the lower mantle. The accumulation of ShyB will generate the low-velocity anomaly in the uppermost lower mantle. The dehydration of ShyB will cause the Vp, Vs, and density increase by 7.5%, 15.0% and 12%, respectively. It means that a slab with 10% ShyB could cause an impedance contrast of 2.7% at a depth of 800 km for shear wave. Furthermore, the released waters by the dehydration of ShyB probably migrate upward and promote the partial melt to reduce the sound velocity at shallower depth, which can further explain the low-velocity zones just above 800-km discontinuity in Western-Pacific Subduction Zones [Liu et al., 2016]. Komabayashi, T., and S. Omori (2006), Internally consistent thermodynamic data set for dense hydrous magnesium silicates up to 35GPa, 1600°C: Implications for water circulation in the Earth's deep mantle, Physics of the Earth and Planetary Interiors, 156(1-2), 89-107. Liu, Z., J. Park, and S. I. Karato (2016), Seismological detection of low-velocity anomalies surrounding the mantle transition

  7. The Relationship between Subclinical Asperger's Syndrome and Frontotemporal Lobar Degeneration

    PubMed Central

    Midorikawa, Akira; Kawamura, Mitsuru

    2012-01-01

    Background/Aims The existence of the behavioral variant of frontotemporal dementia (bv-FTD), including senile Asperger's syndrome (AS), has been proposed. However, there are no empirical case reports to support the proposal. In this report, we present 3 patients who showed symptoms of bv-FTD and demonstrated signs of autistic spectrum disorder, especially AS. Methods We evaluated 3 subjects using the diagnostic criteria for bv-FTD, and their caregivers retrospectively provided data to calculate the Autism-Spectrum Quotient, Japanese version [Wakabayashi et al.: Shinrigaku Kenkyu 2004;75:78–84]. We also compared these data with those obtained from 3 individuals with Alzheimer's disease. Results All 3 patients met the criteria for bv-FTD and had a higher Autism-Spectrum Quotient score than did comparable Alzheimer's disease subjects. Conclusion It is possible that some senile persons with frontotemporal lobar degeneration-like maladaptive behavior may suffer from subclinical AS. PMID:22719743

  8. Larviculture of a carnivorous freshwater catfish, Lophiosilurus alexandri, screened by personality type.

    PubMed

    Torres, Isabela F Araújo; Júlio, Gustavo S da C; Figueiredo, Luis Gustavo; de Lima, Natália L C; Soares, Ana Paula N; Luz, Ronald K

    2017-12-01

    Considering that each personality type in animals presents distinct physiological and behavioural responses, this study evaluated the efficiency of the Novel Environment test to classify larvae of Lophiosilurus alexandri into bold and shy individuals, which were then investigated for growth, cannibalism and mortality in larviculture of pure and mixed groups. Larvae with an average weight of 24.0±1.7mg and length of 14.1±0.4mm, were subjected to a Novel Environment test to classify their personality type (bold and shy larvae). After the larvae were classified according to personality type, they were subjected to larviculture for 15days. Three treatments were tested: only bold larvae, only shy larvae, and a mixed treatment (bold larvae+shy larvae) at a density for 16 larvae/L, which were fed 3 times a day with Artemia nauplii. After larviculture, there were no differences in the final lengths of larvae of the bold, shy, and mixed treatments (26.9±0.76mm, 26.7±1.00mm, and 26.8±1.24mm, respectively); however, shy larvae possessed weighed less (0.22±0.01g) than the bold and mixed treatments, which did not differ significantly (0.25±0.02g and 0.27±0.02g, respectively). The bold and mixed treatments had the highest cannibalism rate (11.2±5.1% and 23.1±12.3%, respectively). Overall survival was lowest in the mixed treatment (62.5±13.0%), while that of the bold and shy treatments were similar (82.5±9.2% and 86.2±9.2%, respectively). The separation of L. alexandri larvae by traits can ensure a decrease in cannibalism and hence, more productive larviculture. Copyright © 2017 Elsevier B.V. All rights reserved.

  9. Taxonomic study of the cricket genus Valiatrella Gorochov (Gryllidae, Podoscirtinae) from China.

    PubMed

    Libin, Ma; Yalin, Zhang

    2013-01-01

    Four Valiatrella species, Valiatrella pulchra (Gorochov, 1985), Valiatrella sororia (Gorochov, 2002), Valiatrella laminaria Liu & Shi, 2007 and Valiatrella multiprotubera Liu & Shi, 2007, recorded from China are reviewed. A new species, Valiatrella persicifolius sp. nov., is described and illustrated.

  10. Exploratory Clinical Trial to Evaluate the Efficacy of a Topical Traditional Chinese Herbal Medicine in Psoriasis Vulgaris

    PubMed Central

    Yan, Yuhe; Liu, Wali; Andres, Philippe; Pernin, Colette; Chantalat, Laurent; Briantais, Philippe; Lin, Albert; Feng, Lilian

    2015-01-01

    Objective. To evaluate the efficacy and safety of herbal ointment, Shi Du Ruan Gao, in patients with plaque-type psoriasis. Design. Single-center, randomized, investigator-blinded, parallel group, placebo-controlled study. Participants. One hundred outpatients with mild to moderate chronic plaque-type psoriasis were enrolled. Intervention. The patients applied either Shi Du Ruan Gao ointment or vehicle ointment topically to for 8 weeks. Main Outcome Measures. The outcomes were assessed using the following criteria: Total Severity Score (TSS, sum of erythema, scaling, and plaque elevation/induration, on a 0 to 4 scale), Investigator Global Assessment (IGA) evaluated on a 0 (Clear) to 4 (s to very severe) scale, and Global Subjects' Assessment of treatment response on a 7-point scale from −1 (worse) to 5 (Cleared). Results. Significant reductions in the Total Severity Score (P < 0.001) (mean score: 2.7 after Shi Du Ruan Gao treatment versus 5.1 in control subjects). Both Investigator Global Assessment (IGA) and Global Subjects' Assessment of treatment are better in the Shi Du Ruan Gao group than the control group (P < 0.001). Conclusion. Shi Du Ruan Gao ointment was a safe, and effective therapy for plaque-type psoriasis. PMID:25834623

  11. From scheme to system: social health insurance funds and the transformation of health financing in Kyrgyzstan and Moldova.

    PubMed

    Kutzin, Joseph; Jakab, Melitta; Shishkin, Sergey

    2009-01-01

    The aim of the paper is to bring evidence and lessons from two low- and middle-income countries (LMIs) of the former USSR into the global debate on health financing in poor countries. In particular, we analyze the introduction of social health insurance (SHI) in Kyrgyzstan and Moldova. To some extent, the intent of SHI introduction in these countries was similar to that in LMIs elsewhere: increase prepaid revenues for health and incorporate the entire population into the new system. But the approach taken to universality was different. In particular, the SHI fund in each country was used as the key instrument in a comprehensive reform of the health financing system, with the new revenues from payroll taxation used in an explicitly complementary manner to general budget revenues. From a functional perspective, the reforms in these countries involved not only the introduction of a new source of funds, but also the centralization of pooling, a shift from input- to output-based provider payment methods, specification of a benefit package, and greater autonomy for public sector health care providers. Hence, their reforms were not simply the introduction of an SHI scheme, but rather the use of an SHI fund as an instrument to transform the entire system of health financing. The study uses administrative and household data to demonstrate the impact of the reforms on regional inequality and household financial burden. The approach used in these two countries led to improved equity in the geographic distribution of government health spending, improved financial protection, and reduced informal payments. The comprehensive approach taken to reform in these two countries, and particularly the redirection of general budget revenues to the new SHI funds, explain much of the success that was achieved. This experience offers potentially useful lessons for LMIs elsewhere in the world, and for shifting the global debate away from what we see as a false dichotomy between SHI and

  12. Social Health Inequalities and eHealth: A Literature Review With Qualitative Synthesis of Theoretical and Empirical Studies.

    PubMed

    Latulippe, Karine; Hamel, Christine; Giroux, Dominique

    2017-04-27

    eHealth is developing rapidly and brings with it a promise to reduce social health inequalities (SHIs). Yet, it appears that it also has the potential to increase them. The general objective of this review was to set out how to ensure that eHealth contributes to reducing SHIs rather than exacerbating them. This review has three objectives: (1) identifying characteristics of people at risk of experiencing social inequality in health; (2) determining the possibilities of developing eHealth tools that avoid increasing SHI; and (3) modeling the process of using an eHealth tool by people vulnerable to SHI. Following the EPPI approach (Evidence for Policy and Practice of Information of the Institute of Education at the University of London), two databases were searched for the terms SHIs and eHealth and their derivatives in titles and abstracts. Qualitative, quantitative, and mixed articles were included and evaluated. The software NVivo (QSR International) was employed to extract the data and allow for a metasynthesis of the data. Of the 73 articles retained, 10 were theoretical, 7 were from reviews, and 56 were based on empirical studies. Of the latter, 40 used a quantitative approach, 8 used a qualitative approach, 4 used mixed methods approach, and only 4 were based on participatory research-action approach. The digital divide in eHealth is a serious barrier and contributes greatly to SHI. Ethnicity and low income are the most commonly used characteristics to identify people at risk of SHI. The most promising actions for reducing SHI via eHealth are to aim for universal access to the tool of eHealth, become aware of users' literacy level, create eHealth tools that respect the cultural attributes of future users, and encourage the participation of people at risk of SHI. eHealth has the potential to widen the gulf between those at risk of SHI and the rest of the population. The widespread expansion of eHealth technologies calls for rigorous consideration of

  13. Social Health Inequalities and eHealth: A Literature Review With Qualitative Synthesis of Theoretical and Empirical Studies

    PubMed Central

    Hamel, Christine; Giroux, Dominique

    2017-01-01

    Background eHealth is developing rapidly and brings with it a promise to reduce social health inequalities (SHIs). Yet, it appears that it also has the potential to increase them. Objectives The general objective of this review was to set out how to ensure that eHealth contributes to reducing SHIs rather than exacerbating them. This review has three objectives: (1) identifying characteristics of people at risk of experiencing social inequality in health; (2) determining the possibilities of developing eHealth tools that avoid increasing SHI; and (3) modeling the process of using an eHealth tool by people vulnerable to SHI. Methods Following the EPPI approach (Evidence for Policy and Practice of Information of the Institute of Education at the University of London), two databases were searched for the terms SHIs and eHealth and their derivatives in titles and abstracts. Qualitative, quantitative, and mixed articles were included and evaluated. The software NVivo (QSR International) was employed to extract the data and allow for a metasynthesis of the data. Results Of the 73 articles retained, 10 were theoretical, 7 were from reviews, and 56 were based on empirical studies. Of the latter, 40 used a quantitative approach, 8 used a qualitative approach, 4 used mixed methods approach, and only 4 were based on participatory research-action approach. The digital divide in eHealth is a serious barrier and contributes greatly to SHI. Ethnicity and low income are the most commonly used characteristics to identify people at risk of SHI. The most promising actions for reducing SHI via eHealth are to aim for universal access to the tool of eHealth, become aware of users’ literacy level, create eHealth tools that respect the cultural attributes of future users, and encourage the participation of people at risk of SHI. Conclusions eHealth has the potential to widen the gulf between those at risk of SHI and the rest of the population. The widespread expansion of e

  14. Family protective factors among urban African American youth.

    PubMed

    McCabe, K M; Clark, R; Barnett, D

    1999-06-01

    Examined the relations among family protective factors, stressful events, and behavioral adjustment of 64 African American 6th graders. The youths reported on family stressors, father-figure involvement, and kin support. Their primary caregivers reported on parenting, father-figure involvement, and family stressors. Teachers reported on child social skill deficits, acting out, and shy or anxious behavior. Based on regression analyses, stress exposure associated positively with child social skill deficits, acting out, and shy or anxious behavior. Parental warmth was associated negatively with shy or anxious behavior. Parental use of corporal punishment was associated positively with child acting out. For youth exposed to high numbers of family stressors, parental demandingness was associated negatively with child acting out and kin support was associated negatively with acting out and shy or anxious behavior, suggesting that these family factors partially shield children from the negative effects of stress.

  15. Dynamics of social health insurance development: examining the determinants of Chinese basic health insurance coverage with panel data.

    PubMed

    Liu, Jun-Qiang

    2011-08-01

    Social health insurance (SHI) is gaining popularity in many developing countries, but there are few systematic empirical studies on the dynamics of SHI development. This study investigates the determinants of coverage of the Basic Healthcare Insurance for Urban Employees (BHI) in China. Using a panel database ranging from 1999 to 2007, the study finds that: (1) economic development plays a valuable role in BHI development; (2) strong financial capacity and administrative capacity in the government contributes to BHI progress; (3) higher trade union density is closely related to more rapid BHI expansion; and (4) taxation agencies are better at collecting SHI premiums. These findings provide evidence-based lessons for new and ongoing SHI programs. In addition, this article aims to make a more general contribution to the study of social policy development by expanding the scope of current theories on social policy development. Copyright © 2011 Elsevier Ltd. All rights reserved.

  16. The influence of shyness on children's test performance.

    PubMed

    Crozier, W Ray; Hostettler, Kirsten

    2003-09-01

    Research has shown that shy children differ from their peers not only in their use of language in routine social encounters but also in formal assessments of their language development, including psychometric tests of vocabulary. There has been little examination of factors contributing to these individual differences. To investigate cognitive-competence and social anxiety interpretations of differences in children's performance on tests of vocabulary. To examine the performance of shy and less shy children under different conditions of test administration, individually with an examiner or among their peers within the familiar classroom setting. The sample consisted of 240 Year 5 pupils (122 male, 118 female) from 24 primary schools. Shy and less shy children, identified by teacher nomination and checklist ratings, completed vocabulary and mental arithmetic tests in one of three conditions, in a between-subjects design. The conditions varied individual and group administration, and oral and written responses. The conditions of test administration influenced the vocabulary test performance of shy children. They performed significantly more poorly than their peers in the two face-to-face conditions but not in the group test condition. A comparable trend for the arithmetic test was not statistically significant. Across the sample as a whole, shyness correlated significantly with test scores. Shyness does influence children's cognitive test performance and its impact is larger when children are tested face-to-face rather than in a more anonymous group setting. The results are of significance for theories of shyness and have implications for the assessment of schoolchildren.

  17. Monitoring political decision-making and its impact in Austria.

    PubMed

    Stepan, Adolf; Sommersguter-Reichmann, Margit

    2005-09-01

    The range of services provided by the Austrian health care system has been greatly extended over the last few decades. The accompanying measures for long-term care bring the situation closer to the ideal concept of a 'seamless web' between primary, secondary and tertiary care. Due to the expansion in services it has become increasingly difficult to ensure the balance between the financing and degree of usage of the services. The reiterated political aim has been to achieve balanced financing via legally fixed social health insurance (SHI) contributions and taxation. A steadily expanding part is contributed by the private sector. In the 1980s, measures for SHI expenditure containment were implemented; in 1997 a new hospital financing system based on flat rates was introduced. In order to guarantee hospital financing, the historical financing shares of the SHI for the hospitals were introduced in the form of valorised global budgets. The contradictory incentives arising from the flat rates and global budgets lead hospitals to shift services to the primary and tertiary care sector, causing additional expenditure for SHI. Currently, attempts are being made to secure the financing by increasing the SHI contribution rates and patients' co-payments. Copyright (c) 2005 John Wiley & Sons, Ltd.

  18. Out of pocket payments and social health insurance for private hospital care: Evidence from Greece.

    PubMed

    Grigorakis, Nikolaos; Floros, Christos; Tsangari, Haritini; Tsoukatos, Evangelos

    2016-08-01

    The Greek state has reduced their funding on health as part of broader efforts to limit the large fiscal deficits and rising debt ratios to GDP. Benefits cuts and limitations of Social Health Insurance (SHI) reimbursements result in substantial Out of Pocket (OOP) payments in the Greek population. In this paper, we examine social health insurance's risk pooling mechanisms and the catastrophic impact that OOP payments may have on insured's income and well-being. Using data collected from a cross sectional survey in Greece, we find that the OOP payments for inpatient care in private hospitals have a positive relationship with SHI funding. Moreover, we show that the SHI funding is inadequate to total inpatient financing. We argue that the Greek health policy makers have to give serious consideration to the perspective of a SHI system which should be supplemented by the Private Health Insurance (PHI) sector. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  19. Influence of Oxygen ions irradiation on Polyaniline/Single Walled Carbon Nanotubes nanocomposite

    NASA Astrophysics Data System (ADS)

    Patil, Harshada K.; Deshmukh, Megha A.; Gaikwad, Sumedh D.; Bodkhe, Gajanan A.; Asokan, K.; Yasuzawa, Mikito; Koinkar, Pankaj; Shirsat, Mahendara D.

    2017-01-01

    Influence of Oxygen ions (100 MeV) irradiation on Polyaniline (PANI)/Single Walled Carbon Nanotubes (SWNTs) nanocomposite was studied in the present investigation. PANI/SWNTs nanocomposite was synthesized by electrochemical Cyclic Voltammetry technique. Nanocomposite was exposed under SHI irradiation of Oxygen (100 MeV) ions for three different fluences such as 1×1010 ions/cm2, 5×1010 ions/cm2 and 1×1011 ions/cm2. The SHI irradiated PANI/SWNTs nanocomposite was investigated by using morphological (AFM), structural (XRD) and spectroscopy (FTIR) characterization. AFM study exhibits effects of SHI irradiation on morphology of the nanocomposite and root mean square roughness of the nanocomposite is observed to be decreased as fluence was increased. The FTIR absorption spectrum exhibits formation of new functional sites with the increase in intensity of absorption peaks, due to SHI irradiation. X-Ray Diffraction studies show a gradual decrease in the crystalline nature of the nanocomposite upon irradiation.

  20. Subclinical hyperthyroidism and cardiovascular risk: recommendations for treatment.

    PubMed

    Palmeiro, Christopher; Davila, Maria I; Bhat, Mallika; Frishman, William H; Weiss, Irene A

    2013-01-01

    Subclinical hyperthyroidism (SHy), the mildest form of hyperthyroidism, is diagnosed in patients having a persistently low or undetectable serum concentration of thyroid-stimulating hormone (TSH) with normal free T4 and T3 concentrations. Although overt hyperthyroidism is associated with an increased risk of adverse cardiovascular outcomes, the cardiovascular risk of SHy is controversial. Multiple studies have demonstrated an increased risk of atrial fibrillation, especially in older individuals with TSH levels <0.1 mU/L. The effects of SHy on all-cause and cardiovascular mortality are not clear, but recent meta-analyses suggest a modest increase in mortality, with the risk increasing with age and associated with the lowest TSH levels. The long-term consequences of SHy in young- and middle-aged adults, and in those with TSH levels are mildly low, are uncertain. For these reasons, guidelines for treatment are based on patient age, the degree of TSH suppression, symptoms consistent with hyperthyroidism, and overall cardiovascular and osteoporotic fracture risks.

  1. TREC 2012 Microblog Track Experiments at Kobe University

    DTIC Science & Technology

    2012-11-01

    query expansion method. References 1. Cao, G., Nie, J.Y., Gao, J ., Robertson, S.: Selecting good expansion terms for pseudo-relevance feedback. In...SIGIR. (2008) 243–250 2. Choi, J ., Croft, W.B.: Temporal models for microblogs. In: CIKM. (2012) 2491–2494 3. Cilibrasi, R.L., Vitanyi, P.M.B.: The...Combining recency and topic-dependent temporal variation for microblog search. In: ECIR. (2013) 14. Ounis, I., Macdonald, C., Lin, J ., Soboroff, I

  2. Sleep hygiene and its association with daytime sleepiness, depressive symptoms, and quality of life in patients with mild obstructive sleep apnea.

    PubMed

    Lee, Sang-Ahm; Paek, Joon-Hyun; Han, Su-Hyun

    2015-12-15

    To investigate the direct and indirect associations of sleep hygiene with daytime sleepiness, depressive symptoms, and quality of life (QoL), in newly diagnosed, untreated patients with mild obstructive sleep apnea (OSA). Data were collected from adults with mild OSA. The Sleep Hygiene Index (SHI), Sleep Problems Index-1 (SPI-1) of the Medical Outcomes Study-Sleep Scale, Epworth Sleepiness Scale (ESS), Beck Depression Inventory (BDI), and Medical Outcomes Study Short-Form Health survey (SF-36) were used to evaluate patients. To determine the indirect and direct associations between SHI and disease outcomes, the Sobel test and multiple linear regression analyses were used, respectively. When we evaluated the direct associations, we excluded 3 items of the original SHI which were more reflective of general health rather than sleep-specific habits and environments. In total, 260 patients with mild OSA participated in this study. The average age, AHI, and SHI scores were 49.1 years (SD 12.5), 9.3/h (SD 2.9), and 24.7 (SD 6.0), respectively. Here, ≥ 10% of participants indicated poor sleep hygiene behaviors on 7 of 13 items. Young age and men were associated with higher SHI scores (both p<0.01). The 13-item SHI scores were indirectly related to ESS, BDI, and SF-36 scores via SPI-1 (all p<0.05). The 10-item SHI scores were related to ESS (p=0.049) and SF-36 (p=0.001), but not to BDI, independently of SPI-1 or other confounding factors in mild OSA patients. Age, sex, AHI, and body mass index were not related to ESS, BDI, or total SF-36 scores. Sleep hygiene is indirectly related to daytime sleepiness, depressive symptoms, QoL via sleep quality and also related to daytime sleepiness and QoL independent of sleep quality in mild OSA patients. Copyright © 2015 Elsevier B.V. All rights reserved.

  3. Cognitive Consequences of the Negative Self.

    ERIC Educational Resources Information Center

    Wurf, Elissa; Markus, Hazel

    Research on self-concept has usually focused on neutral or positive personality characteristics. To determine if negative beliefs about the self have schematic properities, 55 college students, assigned to one of four groups (shy schematics, shy aschematics, independent schematics, independent aschematics), based on a prescreening self-rating on…

  4. Patient-reported symptom questionnaires in laryngeal cancer: voice, speech and swallowing.

    PubMed

    Rinkel, R N P M; Verdonck-de Leeuw, I M; van den Brakel, N; de Bree, R; Eerenstein, S E J; Aaronson, N; Leemans, C R

    2014-08-01

    To validate questionnaires on voice, speech, and swallowing among laryngeal cancer patients, to assess the need for and use of rehabilitation services, and to determine the association between voice, speech, and swallowing problems, and quality of life and distress. Laryngeal cancer patients at least three months post-treatment completed the VHI (voice), SHI (speech), SWAL-QOL (swallowing), EORTC QLQ-C30, QLQ-HN35, HADS, and study-specific questions on rehabilitation. Eighty-eight patients and 110 healthy controls participated. Cut off scores of 15, 6, and 14 were defined for the VHI, SHI, and SWAL-QOL (sensitivity > 90%; specificity > 80%). Based on these scores, 56% of the patients reported voice, 63% speech, and 54% swallowing problems. VHI, SHI, and SWAL-QOL scores were associated significantly with quality of life (EORTC QLQ-C30 global quality of life scale) (r = .43 (VHI and SHI) and r = .46 (SWAL-QOL)) and distress (r = .50 (VHI and SHI) and r = .58 (SWAL-QOL)). In retrospect, 32% of the patients indicated the need for rehabilitation at time of treatment, and 81% of these patients availed themselves of such services. Post-treatment, 8% of the patients expressed a need for rehabilitation, and 20% of these patients actually made use of such services. Psychometric characteristics of the VHI, SHI, and SWAL-QOL in laryngeal cancer patients are good. The prevalence of voice, speech, and swallowing problems is high, and clearly related to quality of life and distress. Although higher during than after treatment, the perceived need for and use of rehabilitation services is limited. Copyright © 2014 Elsevier Ltd. All rights reserved.

  5. Validity of patient-reported swallowing and speech outcomes in relation to objectively measured oral function among patients treated for oral or oropharyngeal cancer.

    PubMed

    Rinkel, R N P M; Verdonck-de Leeuw, I M; de Bree, R; Aaronson, N K; Leemans, C R

    2015-04-01

    The objective of this study was to test the construct validity of the patient-reported outcomes Swallowing Quality of Life Questionnaire (SWAL-QOL) and Speech Handicap Index (SHI) in relation to objectively measured oral function among patients treated for oral or oropharyngeal cancer. The study sample consisted of patients treated for oral or oropharyngeal cancer. Outcome measures were the SWAL-QOL and the SHI, and the Functional Rehabilitation Outcomes Grade (FROG), a test to measure oral and shoulder function. Spearman's rank correlation coefficient was used to test associations between the SHI and SWAL-QOL scales, and the FROG scales. During a study period of 3 months, 38 patients (21 males, 17 females; mean age 54 years) were included who visited the outpatient clinic for follow-up care 6-155 months after surgical treatment (n = 14) or combined surgery and radiotherapy (n = 24) for oral (n = 21) or oropharyngeal cancer (n = 17). Most SWAL-QOL and SHI scales (except the SWAL-QOL Fatigue scale) correlated significantly with one or more FROG oral function scales. None of the SWAL-QOL and SHI scales correlated significantly with the FROG shoulder function scale. These results support the construct validity of the SWAL-QOL and SHI questionnaires for assessing speech and swallowing problems in daily life that are moderately but significantly related to oral function. A multidimensional assessment protocol is recommended for use in clinical practice and for research purposes for measuring oral function and swallowing- and speech-related problems in daily life among head and neck cancer patients.

  6. Extension of NHWAVE to Couple LAMMPS for Modeling Wave Interactions with Arctic Ice Floes

    DTIC Science & Technology

    2014-09-30

    baroclinic non-hydrostatic model”, Ocean Modelling [SUBMITTED]. Bateman , S. Shi, F., Orzech, M., Veeramony, J., and Calantoni, J., 2014, “Discrete...M., Shi, F., Calantoni, J., Bateman , S., and Veeramony, J., “Small-scale modeling of waves and floes in the Marginal Ice Zone”, 2014 Fall Meeting of the American Geophysical Union, [SUBMITTED].

  7. Correlation between muscle structure and filter characteristics of the muscle-joint system in three orthopteran insect species

    PubMed

    BÄSsler; BÜSchges; Meditz; BÄSsler

    1996-01-01

    In orthopteran insects, neural networks for joint control exhibit different characteristics due to behavioural specializations. We investigated whether these differences are generated purely by the neuronal networks, or whether characteristics of the muscles or joint architecture (muscle&shy;joint system) are also involved in these behavioural specializations. We compared the properties of the muscle system moving the femur&shy;tibia joint of the middle and hindleg of three species, Carausius morosus, Cuniculina impigra and Locusta migratoria. Four aspects were analysed for the tibial extensor muscle: (i) the frequency-dependence of motoneuronal activity in response to sinusoidal stimulation of the femoral chordotonal organ (fCO), (ii) the muscle structure, (iii) the innervation pattern of the muscle and (iv) the histochemical properties of the muscle fibres. These aspects were compared with the filter characteristics of the open-loop femur&shy;tibia control system and of the muscle&shy;joint system involved. Whereas in both phasmid species (Carausius morosus and Cuniculina impigra) the motoneuronal activity steadily increases with sinusoidal stimulation of the fCO in the frequency range 0.01&shy;5 Hz, in Locusta migratoria there is a decrease in motoneuronal activity between 0.01 and 0.3 Hz. The muscle structure is basically similar in all three species, as the number of singly innervated muscle fibres (supplied by the fast extensor tibiae motor neurone, FETi) decreases from proximal to distal. The number of triply innervated fibres supplied by the FETi, the slow extensor tibiae (SETi) and the common inhibitor 1 (CI1) is maximal in the middle of the muscle, and the number of dually innervated fibres (supplied by SETi, CI1) increases from proximal to distal. Differences between the locust and the two phasmid species exist in the distal portion of the muscle. The phasmid extensor tibiae muscle contains a morphologically distinct bundle of muscle fibres, not present

  8. Payments and quality of care in private for-profit and public hospitals in Greece

    PubMed Central

    2011-01-01

    Background Empirical evidence on how ownership type affects the quality and cost of medical care is growing, and debate on these topics is ongoing. Despite the fact that the private sector is a major provider of hospital services in Greece, little comparative information on private versus public sector hospitals is available. The aim of the present study was to describe and compare the operation and performance of private for-profit (PFP) and public hospitals in Greece, focusing on differences in nurse staffing rates, average lengths of stay (ALoS), and Social Health Insurance (SHI) payments for hospital care per patient discharged. Methods Five different datasets were prepared and analyzed, two of which were derived from information provided by the National Statistical Service (NSS) of Greece and the other three from data held by the three largest SHI schemes in the country. All data referred to the 3-year period from 2001 to 2003. Results PFP hospitals in Greece are smaller than public hospitals, with lower patient occupancy, and have lower staffing rates of all types of nurses and highly qualified nurses compared with public hospitals. Calculation of ALoS using NSS data yielded mixed results, whereas calculations of ALoS and SHI payments using SHI data gave results clearly favoring the public hospital sector in terms of cost-efficiency; in all years examined, over all specialties and all SHI schemes included in our study, unweighted ALoS and SHI payments for hospital care per discharge were higher for PFP facilities. Conclusions In a mixed healthcare system, such as that in Greece, significant performance differences were observed between PFP and public hospitals. Close monitoring of healthcare provision by hospital ownership type will be essential to permit evidence-based decisions on the future of the public/private mix in terms of healthcare provision. PMID:21943020

  9. Preliminary results for mask metrology using spatial heterodyne interferometry

    NASA Astrophysics Data System (ADS)

    Bingham, Philip R.; Tobin, Kenneth; Bennett, Marylyn H.; Marmillion, Pat

    2003-12-01

    Spatial heterodyne interferometry (SHI) is an imaging technique that captures both the phase and amplitude of a complex wavefront in a single high-speed image. This technology was developed at the Oak Ridge National Laboratory (ORNL) and is currently being implemented for semiconductor wafer inspection by nLine Corporation. As with any system that measures phase, metrology and inspection of surface structures is possible by capturing a wavefront reflected from the surface. The interpretation of surface structure heights for metrology applications can become very difficult with the many layers of various materials used on semiconductor wafers, so inspection (defect detection) has been the primary focus for semiconductor wafers. However, masks used for photolithography typically only contain a couple well-defined materials opening the doors to high-speed mask metrology in 3 dimensions in addition to inspection. Phase shift masks often contain structures etched out of the transparent substrate material for phase shifting. While these structures are difficult to inspect using only intensity, the phase and amplitude images captured with SHI can produce very good resolution of these structures. The phase images also provide depth information that is crucial for these phase shift regions. Preliminary testing has been performed to determine the feasibility of SHI for high-speed non-contact mask metrology using a prototype SHI system with 532 nm wavelength illumination named the Visible Alpha Tool (VAT). These results show that prototype SHI system is capable of performing critical dimension measurements on 400nm lines with a repeatability of 1.4nm and line height measurements with a repeatability of 0.26nm. Additionally initial imaging of an alternating aperture phase shift mask has shown the ability of SHI to discriminate between typical phase shift heights.

  10. Payments and quality of care in private for-profit and public hospitals in Greece.

    PubMed

    Kondilis, Elias; Gavana, Magda; Giannakopoulos, Stathis; Smyrnakis, Emmanouil; Dombros, Nikolaos; Benos, Alexis

    2011-09-23

    Empirical evidence on how ownership type affects the quality and cost of medical care is growing, and debate on these topics is ongoing. Despite the fact that the private sector is a major provider of hospital services in Greece, little comparative information on private versus public sector hospitals is available. The aim of the present study was to describe and compare the operation and performance of private for-profit (PFP) and public hospitals in Greece, focusing on differences in nurse staffing rates, average lengths of stay (ALoS), and Social Health Insurance (SHI) payments for hospital care per patient discharged. Five different datasets were prepared and analyzed, two of which were derived from information provided by the National Statistical Service (NSS) of Greece and the other three from data held by the three largest SHI schemes in the country. All data referred to the 3-year period from 2001 to 2003. PFP hospitals in Greece are smaller than public hospitals, with lower patient occupancy, and have lower staffing rates of all types of nurses and highly qualified nurses compared with public hospitals. Calculation of ALoS using NSS data yielded mixed results, whereas calculations of ALoS and SHI payments using SHI data gave results clearly favoring the public hospital sector in terms of cost-efficiency; in all years examined, over all specialties and all SHI schemes included in our study, unweighted ALoS and SHI payments for hospital care per discharge were higher for PFP facilities. In a mixed healthcare system, such as that in Greece, significant performance differences were observed between PFP and public hospitals. Close monitoring of healthcare provision by hospital ownership type will be essential to permit evidence-based decisions on the future of the public/private mix in terms of healthcare provision.

  11. Two new species of the genus Xizicus (Orthoptera: Tettigoniidae: Meconematinae) in China.

    PubMed

    Di, Juan-Xia; Han, Li; Mao, Shao-Li; Shi, Fu-Ming

    2015-08-26

    Two new species of the genus Xizicus are described, namely Xizicus (Eoxizicus) uncicercus Mao & Shi sp. nov. and Xizicus (Eoxizicus) dischidus Di, Han & Shi sp. nov. from China, in addition, photographs of morphological structure of the species are provided. All type specimens are deposited in the Museum of Hebei University, Baoding, P. R. China.

  12. Applying the School Health Index to a Nationally Representative Sample of Schools

    ERIC Educational Resources Information Center

    Brener, Nancy D.; Pejavara, Anu; Barrios, Lisa C.; Crossett, Linda; Lee, Sarah M.; McKenna, Mary; Michael, Shannon; Wechsler, Howell

    2006-01-01

    The School Health Index (SHI) is a self-assessment and planning tool that helps individual schools identify the strengths and weaknesses of their health policies and programs. To determine the percentage of US schools meeting the recommendations in the SHI, the present study analyzed data from the School Health Policies and Programs Study (SHPPS)…

  13. PREFACE: NC-AFM 2006: Proceedings of the 9th International Conference on Non-contact Atomic Force Microscopy

    NASA Astrophysics Data System (ADS)

    Tomitori, Masahiko; Onishi, Hiroshi

    2007-02-01

    The advent of scanning probe microscopy (SPM) in the 1980s has significantly promoted nanoscience and nanotechnology. In particular, non-contact atomic force microscopy (NC-AFM), one of the SPM family, has unique capabilities with high spatial resolution for nanoscale measurements in vacuum, air and liquids. In the last decade we have witnessed the rapid progress of NC-AFM with improved performance and increasing applications. A series of NC-AFM international conferences have greatly contributed to this field. Initiated in Osaka in 1998, the NC-AFM meeting has been followed by annual conferences at Pontresina, Hamburg, Kyoto, Montreal, Dingle, Seattle and Bad Essen. The 9th conference was held in Kobe, Japan, 16-20 July 2006. This special issue of Nanotechnology contains the outstanding contributions of the conference. During the meeting delegates learnt about a number of significant advances. Topics covered atomic resolution imaging of metals, semiconductors, insulators, ionic crystals, oxides, molecular systems, imaging of biological materials in various environments and novel instrumentation. Work also included the characterization of electronic and magnetic properties, tip and cantilever fabrication and characterization, atomic distinction based on analysis of tip-sample interaction, atomic scale manipulation, fabrication of nanostructures using NC-AFM, and related theories and simulations. We are greatly impressed by the increasing number of applications, and convinced that NC-AFM and related techniques are building a bridge to a future nano world, where quantum phenomena will dominate and nano devices will be realized. In addition, a special session on SPM road maps was held as a first trial in the field, where the future prospects of SPM were discussed enthusiastically. The overall success of the NC-AFM 2006 conference was due to the efforts of many individuals and groups with respect to scientific and technological progress, as well as the international

  14. [Carving and spread of Xu Shuwei's medical books in the Southern Song Dynasty].

    PubMed

    Zhang, Haipeng

    2015-09-01

    Xu Shuwei's Pu ji ben shi fang (Moxibustion in Prescription for Universal Relief) was carved for several times and disseminated to Hubei, Hunan, Zhejiang, Jiangsu, Fujian, Sichuan Provinces and the areas under the rule of the Jin ethnic minority group. While Shang han bai zheng ge (Poets of Syndrome of Exo-pathogenic Cold disease), Shang han fa wei lun (Discourse on Elucidation of Exo-pathogenic Cold Disease), and Shang han jiu shi lun (90 Discourses on Exo-pathogenic Disease) were scarcely carved or spread in its copying form with very limited distribution. Hence, Pu ji ben shi fang exerts greater influence in the Southern Song Dynasty. When analysing the citations from the Pu ji ben sgiu fang in the books of the Southern Song Dynasty, very few texts were cited from Pu ji ben shi fang. Thus, in terms of knowledge on exo-pathogenic cold disease in the Southern Song Dynasty, Xu's influence was quite limited even though he himself had deep insight into this art of disease.

  15. KSC-02pd0736

    NASA Image and Video Library

    2002-05-16

    KENNEDY SPACE CENTER, FLA. - Suspended from the overhead crane, the SHI Research Double Module (SHI/RDM) travels across the Space Station Processing Facility to the payload canister waiting at right. The module will be placed in the canister for transport to the Orbiter Processing Facility where it will be installed in Columbia's payload bay for mission STS-107. SHI/RDM is the primary payload of the research mission, with experiments ranging from material sciences to life sciences (many rats). Also part of the payload is the Fast Reaction Experiments Enabling Science, Technology, Applications and Research (FREESTAR) that incorporates eight high priority secondary attached shuttle experiments. STS-107 is scheduled to launch July 19, 2002

  16. Distribution of stress drop, stiffness, and fracture energy over earthquake rupture zones

    USGS Publications Warehouse

    Fletcher, Joe B.; McGarr, A.

    2006-01-01

    Using information provided by slip models and the methodology of McGarr and Fletcher (2002), we map static stress drop, stiffness (k = ????/u, where ???? is static stress drop and u is slip), and fracture energy over the slip surface to investigate the earthquake rupture process and energy budget. For the 1994 M6.7 Northridge, 1992 M7.3 Landers, and 1995 M6.9 Kobe earthquakes, the distributions of static stress drop show strong heterogeneity, emphasizing the importance of asperities in the rupture process. Average values of static stress drop are 17, 11, and 4 Mpa for Northridge, Landers, and Kobe, respectively. These values are substantially higher than estimates based on simple crack models, suggesting that the failure process involves the rupture of asperities within the larger fault zone. Stress drop as a function of depth for the Northridge and Landers earthquakes suggests that stress drops are limited by crustal strength. For these two earthquakes, regions of high slip are surrounded by high values of stiffness. Particularly for the Northridge earthquake, the prominent patch of high slip in the central part of the fault is bordered by a ring of high stiffness and is consistent with expectations based on the failure of an asperity loaded at its edge due to exterior slip. Stiffness within an asperity is inversely related to its dimensions. Estimates of fracture energy, based on static stress drop, slip, and rupture speed, were used to investigate the nature of slip weakening at four locations near the hypocenter of the Kobe earthquake for comparison with independent results based on a dynamic model of this earthquake. One subfault updip and to the NE of the hypocenter has a fracture energy of 1.1 MJ/m2 and a slip-weakening distance, Dc, of 0.66 m. Right triangles, whose base and height are Dc and the dynamic stress drop, respectively, approximately overlie the slip-dependent stress given by Ide and Takeo (1997) for the same locations near the hypocenter. The

  17. Caught between Fantasy and Reality: Confucian Values and Dilemmas of Education Reform Confronting Hong Kong's Secondary Teachers

    ERIC Educational Resources Information Center

    Tam, Frank Wai-Ming; Lai, Manhong; Lam, Ka-Ka

    2007-01-01

    In Chinese society, there are two Confucian teachings that have become guiding values for many teachers and have had profound influence on their educational practices for nearly 2,500 years. These values are "yin cai shi jiao" and "you jiao wu lei." The direct translation of yin cai shi jiao is "to carry out teaching based…

  18. Applications of a Sequence of Points in Teaching Linear Algebra, Numerical Methods and Discrete Mathematics

    ERIC Educational Resources Information Center

    Shi, Yixun

    2009-01-01

    Based on a sequence of points and a particular linear transformation generalized from this sequence, two recent papers (E. Mauch and Y. Shi, "Using a sequence of number pairs as an example in teaching mathematics". Math. Comput. Educ., 39 (2005), pp. 198-205; Y. Shi, "Case study projects for college mathematics courses based on a particular…

  19. Akashi Kaikyo Bridge, Japan

    NASA Image and Video Library

    2013-03-25

    NASA Terra spacecraft shows the Akashi Kaikyo Bridge or Pearl Bridge, the longest central span of any suspension bridge in the world, at 1991 meters, connecting the city of Kobe, Japan with Iwaja on Awaji Island by crossing the busy Akashi Strait.

  20. Dual-pulse frequency compounded superharmonic imaging.

    PubMed

    van Neer, Paul L M J; Danilouchkine, Mikhail G; Matte, Guillaume M; van der Steen, Anton F W; de Jong, Nico

    2011-11-01

    Tissue second-harmonic imaging is currently the default mode in commercial diagnostic ultrasound systems. A new modality, superharmonic imaging (SHI), combines the third through fifth harmonics originating from nonlinear wave propagation through tissue. SHI could further improve the resolution and quality of echographic images. The superharmonics have gaps between the harmonics because the transducer has a limited bandwidth of about 70% to 80%. This causes ghost reflection artifacts in the superharmonic echo image. In this work, a new dual-pulse frequency compounding (DPFC) method to eliminate these artifacts is introduced. In the DPFC SHI method, each trace is constructed by summing two firings with slightly different center frequencies. The feasibility of the method was established using a single-element transducer. Its acoustic field was modeled in KZK simulations and compared with the corresponding measurements obtained with a hydrophone apparatus. Subsequently, the method was implemented on and optimized for a setup consisting of an interleaved phased-array transducer (44 elements at 1 MHz and 44 elements at 3.7 MHz, optimized for echocardiography) and a programmable ultrasound system. DPFC SHI effectively suppresses the ghost reflection artifacts associated with imaging using multiple harmonics. Moreover, compared with the single-pulse third harmonic, DPFC SHI improved the axial resolution by 3.1 and 1.6 times at the -6-dB and -20-dB levels, respectively. Hence, DPFC offers the possibility of generating harmonic images of a higher quality at a cost of a moderate frame rate reduction.

  1. Severe spontaneous hemoperitoneum in pregnancy may be linked to in vitro fertilization in patients with endometriosis: a systematic review.

    PubMed

    Brosens, Ivo A; Lier, Marit C; Mijatovic, Velja; Habiba, Marwan; Benagiano, Giuseppe

    2016-09-01

    To evaluate existing evidence of a possible association in women with endometriosis between controlled ovarian hyperstimulation plus embryo transfer (COH-ET) and the occurrence of spontaneous hemoperitoneum in pregnancy (SHiP). Comprehensive review. Not applicable. None. An electronic literature search up to February 2016 was conducted using Scopus and PubMed. The role of COH-ET in SHiP. Controlled ovarian hyperstimulation plus embryo transfer may increase the severity or incidence of the rare condition known as SHiP. An analysis of published cases shows that bleeding often occurs from multiple or diffuse sites, mainly situated in the posterior pelvic cavity, making it difficult to control without interfering with the pregnancy itself. Spontaneous hemoperitoneum in pregnancy is linked to adverse perinatal outcomes, including stillbirth, neonatal mortality, and very low or low birth weight. In 14 cases a biopsy of the bleeding site was obtained, and in all cases, even in the absence of visible endometriosis, decidualization was documented. At present, the relatively small number of cases published prevents firm conclusions, although they are highly suggestive of a link between COH-ET in women with endometriosis and the occurrence and seriousness of SHiP. Spontaneous hemoperitoneum in pregnancy is a rare but potentially fatal complication for the pregnant woman and her unborn child. In vitro fertilization in women with severe endometriosis may be a risk factor for SHiP. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

  2. Peak-Power Markets for Satellite Solar Power

    NASA Astrophysics Data System (ADS)

    Landis, G.

    2002-01-01

    Aman MOSTAVANNobuyuki KAYA Institut Teknologi Bandung (TF)Kobe University, Rokkodai, Nada, Ganesha 10; Bandung 40132, IndonesiaKobe 657, Japan mostavan@tf.itb.ac.idkaya@kobe-u.ac.jp This paper introduces first Indonesia, comprises 15 000 islands, has land area of two millions square kilometers. Extending from 95 to 141 degrees East longitude and from 6 degrees North to 11 degrees South latitude. Further the market of the Space Solar Power/SPS must be worldwide, including Indonesia. As we know, it can provide electricity anywhere in the world from the Earth's orbit, mostly Indonesia an equator country. We have to perform case studies of various countries to understand their benefits and disadvantages provided by the SSP, because each country has much different condition on energy from other countries. We are at the moment starting the international collaboration between Indonesia and Japan to carry out the case study for Indonesia. We understand that in Indonesia itself each province has much different micro-climate between one province compared to the other. In Japan, METI (Ministry of Economy, Trade and Industry) has already organized a committee to investigate the feasibility of Space Solar Power and to make a plan to launch a space demonstration of the SPS. While, Indonesia is quickly developing economy and increasing their energy demand. We are investigating the detailed energy conditions of Indonesia, the benefits and disadvantages of the Space Solar Power for Indonesia. Especially, we will perform the investigation on the receiving system for the Japanese pilot Space Power Satellite.

  3. Redistribution through social health insurance: evidence on citizen preferences.

    PubMed

    Pfarr, Christian; Schmid, Andreas

    2016-06-01

    The extent of social health insurance (SHI) and supplementary private insurance is frequently analyzed in public choice. Most of these analyses build on the model developed by Gouveia (1997), who defines the extent of SHI as consequence of a choice by self-interested voters. In this model, an indicator reflecting individuals' relative income position and relative risk of falling ill determines the voting decision. Up to now, no empirical evidence for this key assumption has been available. We test the effect of this indicator on individuals' preferences for the extent of SHI in a setting with mandatory SHI that can be supplemented by private insurance. The data is based on a DCE conducted in the field with a representative sample of 1538 German citizens in 2012. Conditional logit and latent class models are used to analyze preference heterogeneity. Our findings strongly support the assumptions of the models. Individuals likely to benefit from public coverage show a positive marginal willingness to pay (MWTP) for both a shift away from other beneficiary groups toward the sick and an expansion of publicly financed resources, and the expected net payers have a negative MWTP and prefer lower levels of public coverage.

  4. Once a physicist: Zhengrong Shi

    NASA Astrophysics Data System (ADS)

    Shi, Zhengrong

    2009-02-01

    Why did you choose to study physics? I was born on an island called Yangzhong on the Yangtze River in Jiangsu province, China. Though mainly agricultural, Yangzhong was blessed with a good school system and I dedicated myself to my studies. I followed my instincts and interests in science and built a strong foundation in physics. My family always encouraged me to pursue my studies, so I went on to obtain a Bachelor°s degree in optical science from Chang Chun University of Science and Technology in 1983 and a Master°s degree in laser physics from the Shanghai Institute of Optics and Fine Mechanics in 1986.

  5. Transnational Culture and the Role of Language: An International School and Its Community.

    ERIC Educational Resources Information Center

    Willis, David B.

    1992-01-01

    Describes the environment and cultural at Columbia Academy, a private international high school in Kobe, Japan. Emphasizes the role of language and how second-language skills represent learned cultural competencies. Considers the influence of language use on group behaviors. Addresses the issue of transnationalism or transculturalism. (DMM)

  6. Plasticity of boldness in rainbow trout, Oncorhynchus mykiss: do hunger and predation influence risk-taking behaviour?

    PubMed

    Thomson, Jack S; Watts, Phillip C; Pottinger, Tom G; Sneddon, Lynne U

    2012-05-01

    Boldness, a measure of an individual's propensity for taking risks, is an important determinant of fitness but is not necessarily a fixed trait. Dependent upon an individual's state, and given certain contexts or challenges, individuals may be able to alter their inclination to be bold or shy in response. Furthermore, the degree to which individuals can modulate their behaviour has been linked with physiological responses to stress. Here we attempted to determine whether bold and shy rainbow trout, Oncorhynchus mykiss, can exhibit behavioural plasticity in response to changes in state (nutritional availability) and context (predation threat). Individual trout were initially assessed for boldness using a standard novel object paradigm; subsequently, each day for one week fish experienced either predictable, unpredictable, or no simulated predator threat in combination with a high (2% body weight) or low (0.15%) food ration, before being reassessed for boldness. Bold trout were generally more plastic, altering levels of neophobia and activity relevant to the challenge, whereas shy trout were more fixed and remained shy. Increased predation risk generally resulted in an increase in the expression of three candidate genes linked to boldness, appetite regulation and physiological stress responses - ependymin, corticotrophin releasing factor and GABA(A) - but did not produce a significant increase in plasma cortisol. The results suggest a divergence in the ability of bold and shy trout to alter their behavioural profiles in response to internal and exogenous factors, and have important implications for our understanding of the maintenance of different behavioural phenotypes in natural populations. Copyright © 2012 Elsevier Inc. All rights reserved.

  7. Distributions of polycyclic aromatic hydrocarbons and alkylated polycyclic aromatic hydrocarbons in Osaka Bay, Japan.

    PubMed

    Miki, Shizuho; Uno, Seiichi; Ito, Kazuki; Koyama, Jiro; Tanaka, Hiroyuki

    2014-08-30

    Contaminations in sediments by polycyclic aromatic hydrocarbons (PAHs) and alkylated PAHs were investigated at 44 sites in Osaka Bay, Japan. Concentrations of total PAHs and alkylated PAHs were in the range 6.40-7800 ng/g dry weights and 13.7-1700 ng/g dry weights, respectively. The PAH concentrations tended to be higher along the shoreline in the vicinities of big ports, industrialized areas, and densely populated regions such as the cities of Osaka and Kobe. The major sources appeared to be pyrogenic or both pyrogenic and petrogenic at most of the sites. PAH concentrations were remarkably high at a site near Kobe, where the concentrations of dibenzo(a,h)anthracene and benzo(g,h,i)perylene exceeded the effects-range-medium concentration and eight PAHs were above the corresponding effects-range-low concentrations. Those PAHs may have been derived from the great fire associated with the large earthquake in 1995. Copyright © 2014 Elsevier Ltd. All rights reserved.

  8. Black Holes and Qubits

    NASA Astrophysics Data System (ADS)

    Borsten, L.; Duff, M. J.; Rubens, W.

    These notes have been compiled to accompany a series of four lectures given at the Kinki University Quantum Computing Series Summer School on Decoherence, Entanglement and Entropy, August 2009 at the Oxford Kobe Institute (Kobe, Japan). Each of the four lectures focuses on a particular topic falling under the broad umbrella of the "black-hole/qubit correspondence". Lecture I introduces the first instance of the black-hole/qubit correspondence, the relationship between the entanglement of three qubits and the entropy of STU black holes. Lecture II develops this correspondence to the case of {N} = 8 black holes and the tripartite entanglement of seven qubits. Lecture III examines the use of Jordan algebras and the Freudenthal triple system, which capture the U-duality symmetries of these black hole systems, in entanglement classification. Lecture IV introduces the superqubit, a natural candidate to represent supersymmetric quantum information. These lectures draw on work done with D. Dahanayake, H. Ebrahim, S. Ferrara and A. Marrani whose efforts are most gratefully acknowledged.

  9. Experiments on Condensed Matter Nuclear Events in Kobe University

    NASA Astrophysics Data System (ADS)

    Minari, T.; Nishio, R.; Taniike, A.; Furuyama, Y.; Kitamura, A.

    2006-02-01

    We review three kinds of experimental works underway in our laboratory to investigate nuclear events in solid or liquid materials. The largest effort has been given to experiments to confirm the 7Li(d, n2α) reaction rate enhancement reaching 1015 in liquid lithium which was reported by H. Ikegami and R. Pettersson, Evidence of Enhanced Nonthermal Nuclear Fusion (Bulletin of Institute of Chemistry, BENF No. 3, Uppsala University, Sweden, September 2002). Li liquid droplets are formed as targets, and to keep them as pure as possible, we built a liquid Li loop. Thus far, in all cases of irradiation at the temperature from 520 to 570 K with 10-24 keV deuterons, we have not been able to reproduce the Ikegami enhancement for the 7Li(d, n2α) reaction.

  10. KSC-02pd0978

    NASA Image and Video Library

    2002-06-14

    KENNEDY SPACE CENTER, FLA. - -- Columbia's payload bay doors are ready to be closed for mission STS-107. Installed inside are the Hitchhiker Bridge, a carrier for the Fast Reaction Experiments Enabling Science, Technology, Applications and Research (FREESTAR) that incorporates eight high priority secondary attached shuttle experiments, plus the SHI Research Double Module (SHI/RDM), also known as SPACEHAB. STS-107 is scheduled for launch July 19, 2001

  11. Induction of a Pregnancy-Like Mammary Gland Differentiation by Docosapentaenoic Omega-3 Fatty Acid

    DTIC Science & Technology

    2010-09-01

    0375 TITLE: Induction of a Pregnancy-Like Mammary Gland Differentiation by Docosapentaenoic Omega-3 Fatty Acid PRINCIPAL INVESTIGATOR: Shi...Fatty Acid 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER Shi, Y. Eric 5e. TASK NUMBER Email: eshi...cells during pregnancy. Considerable evidences suggest strongly that the n-3 polyunsaturated fatty acid (PUFA) content of adipose breast tissue is

  12. Prevalence and Correlates of Self-Harm in the German General Population

    PubMed Central

    Müller, Astrid; Claes, Laurence; Smits, Dirk; Brähler, Elmar; de Zwaan, Martina

    2016-01-01

    The study aimed at evaluating the psychometric properties of the German version of the Self- Harm Inventory (SHI) and examining the lifetime prevalence and correlates of self-harm in a representative German population sample (N = 2,507; age mean = 48.79, SD = 18.11; range 14 to 94 years; 55.5% women) using the SHI. All participants answered the German SHI, the short form of the Barratt Impulsiveness Scale (BIS-15), the ultra-brief Patient Health Questionnaire for Depression and Anxiety (PHQ-4), and provided sociodemographic information. The one-factorial structure of the SHI was replicated using a confirmatory factor analysis. Internal consistency coefficients were sufficient and in line with previous studies. Almost half of the sample (49%) acknowledged at least one self-harming behavior over the life-span, most frequently indirect forms of self-harm. The rate of participants who engaged in at least one SHI behavior was higher among men than women (51.6% vs. 46.9%, respectively, χ2 = 5.38, p = 0.020). Higher SHI scores were related to younger age, male gender, living alone, more symptoms of anxiety and depression (PHQ-4), higher impulsivity scores (BIS-15), and suffering from obesity grade 2. Women engaged more often in discreet forms of self-harm than men, e.g., preventing wounds from healing, exercising an injury, starving, and abusing laxatives. In terms of other indirect self-harming behaviors, men admitted more often driving recklessly, being promiscuous and losing a job on purpose, while women reported more frequently engaging in emotionally abusive relationships. With respect to direct self-harm, women were more likely to endorse suicide attempts and cutting, while men admitted more often head-banging. The findings suggest that self-harm constitutes a common problem. Future longitudinal studies are required to examine the natural course, sociodemographic and psychopathological risk factors, as well as possible time-trends of self-harming behaviors in more

  13. Prevalence and Correlates of Self-Harm in the German General Population.

    PubMed

    Müller, Astrid; Claes, Laurence; Smits, Dirk; Brähler, Elmar; de Zwaan, Martina

    2016-01-01

    The study aimed at evaluating the psychometric properties of the German version of the Self- Harm Inventory (SHI) and examining the lifetime prevalence and correlates of self-harm in a representative German population sample (N = 2,507; age mean = 48.79, SD = 18.11; range 14 to 94 years; 55.5% women) using the SHI. All participants answered the German SHI, the short form of the Barratt Impulsiveness Scale (BIS-15), the ultra-brief Patient Health Questionnaire for Depression and Anxiety (PHQ-4), and provided sociodemographic information. The one-factorial structure of the SHI was replicated using a confirmatory factor analysis. Internal consistency coefficients were sufficient and in line with previous studies. Almost half of the sample (49%) acknowledged at least one self-harming behavior over the life-span, most frequently indirect forms of self-harm. The rate of participants who engaged in at least one SHI behavior was higher among men than women (51.6% vs. 46.9%, respectively, χ2 = 5.38, p = 0.020). Higher SHI scores were related to younger age, male gender, living alone, more symptoms of anxiety and depression (PHQ-4), higher impulsivity scores (BIS-15), and suffering from obesity grade 2. Women engaged more often in discreet forms of self-harm than men, e.g., preventing wounds from healing, exercising an injury, starving, and abusing laxatives. In terms of other indirect self-harming behaviors, men admitted more often driving recklessly, being promiscuous and losing a job on purpose, while women reported more frequently engaging in emotionally abusive relationships. With respect to direct self-harm, women were more likely to endorse suicide attempts and cutting, while men admitted more often head-banging. The findings suggest that self-harm constitutes a common problem. Future longitudinal studies are required to examine the natural course, sociodemographic and psychopathological risk factors, as well as possible time-trends of self-harming behaviors in more

  14. Development of an Operational Multi-sensor and Multi-channel Aerosol Assimilation Package

    DTIC Science & Technology

    2011-08-18

    2010, EGU General Assembly 2010. Shi, Y., J. Zhang, J. S. Reid, E. Hyer, Evaluation of MISR Aerosol Optical Depth Product for Aerosol Data...empirical correction procedures for generating data-assimilation-friendly over-water MODIS aerosol products. This study has been published (Shi et al...type as large r\\ values are generally related to fine mode aerosols, such as sulfate and smoke aerosols, and small r\\ values typically indicate sea

  15. Applying the School Health Index to a nationally representative sample of schools: update for 2006.

    PubMed

    Brener, Nancy D; Pejavara, Anu; McManus, Tim

    2011-02-01

    The School Health Index (SHI) is a tool designed to help schools assess the extent to which they are implementing practices included in the research-based guidelines and strategies for school health and safety programs developed by the Centers for Disease Control and Prevention (CDC). CDC previously analyzed data from the 2000 School Health Policies and Programs Study (SHPPS) to determine the percentage of US schools meeting the recommendations in the SHI. A new edition of the SHI (2005) and the availability of 2006 SHPPS data made it necessary to update and repeat the analysis. SHPPS 2006 data were collected through computer-assisted personal interviews with faculty and staff in a nationally representative sample of schools. The data were then matched to SHI items to calculate the percentage of schools meeting the recommendations in 4 areas: school health and safety policies and environment, health education, physical education and other physical activity programs, and nutrition services. In accordance with the earlier findings, the present analysis indicated that schools nationwide were focusing their efforts on a few policies and programs rather than addressing the entire set of recommendations in the SHI. The percentage of items related to nutrition that schools met remained high, and an increase occurred in the percentage of items that schools met related to school health and safety policies and environment. More work needs to be done to assist schools in implementing school health policies and practices; this analysis helps identify specific areas where improvement is needed. © Published 2011. This article is a US Government work and is in the public domain in the USA.

  16. Towards Universal Health Coverage via Social Health Insurance in China: Systemic Fragmentation, Reform Imperatives, and Policy Alternatives.

    PubMed

    He, Alex Jingwei; Wu, Shaolong

    2017-12-01

    China's remarkable progress in building a comprehensive social health insurance (SHI) system was swift and impressive. Yet the country's decentralized and incremental approach towards universal coverage has created a fragmented SHI system under which a series of structural deficiencies have emerged with negative impacts. First, contingent on local conditions and financing capacity, benefit packages vary considerably across schemes, leading to systematic inequity. Second, the existence of multiple schemes, complicated by massive migration, has resulted in weak portability of SHI, creating further barriers to access. Third, many individuals are enrolled on multiple schemes, which causes inefficient use of government subsidies. Moral hazard and adverse selection are not effectively managed. The Chinese government announced its blueprint for integrating the urban and rural resident schemes in early 2016, paving the way for the ultimate consolidation of all SHI schemes and equal benefits for all. This article proposes three policy alternatives to inform the consolidation: (1) a single-pool system at the prefectural level with significant government subsidies, (2) a dual-pool system at the prefectural level with risk-equalization mechanisms, and (3) a household approach without merging existing pools. Vertical integration to the provincial level is unlikely to happen in the near future. Two caveats are raised to inform this transition towards universal health coverage.

  17. Health instruction in Nigerian schools: what are the missing links?

    PubMed Central

    Olatunya, Oladele Simeon; Oseni, Saheed Babajide; Oyelami, Oyeku Akibu; Adegbenro, Caleb; Akani, Nwadiuto

    2014-01-01

    Introduction School health instruction (SHI) is the instructional aspects of school health programme. It provides information on key health issues to school children who are in their formative years. Methods A cross sectional descriptive study of all the primary schools in a focal Local Government Area in Nigeria was carried out to ascertain the implementation of SHI with regards to the contents, methods of delivery and teachers preparation for health teaching using an evaluation checklist for SHI. Results There were more female pupils enrolled in the study area compared to their male counterparts with a male to female ratio of 0.9:1.0 and only 3.0% of the teachers had In-service training on health related issues in the previous five years preceding the study. 79.4% of the teachers had the recommended qualification to work in the schools. Teachings on emotional health, communicable diseases and safety education were sparingly given by 1.6%, 4.7% and 56% schools respectively. Only three (4.7%) schools (all private) had health instruction given by designated health education staff. No school gave health instruction at least thrice a week as recommended. Conclusion Compliance with the implementation of SHI was very poor in the study area. PMID:25932073

  18. Severe hearing impairment among military veterans--United States, 2010.

    PubMed

    2011-07-22

    A substantial proportion of hearing loss in the United States is attributable to employment-related exposure to noise. Among military veterans, the most common service-connected disabilities are hearing impairments, suggesting that occupational noise exposure during military service might cause more veterans to have hearing loss than nonveterans. However, a recent analysis of data from the 1993-1995 Epidemiology of Hearing Loss Study did not find significant differences between the two groups. To further investigate hearing loss among veterans, specifically the prevalence of severe hearing impairment (SHI), data from the 2010 Annual Social and Economic Supplement (ASEC) to the Current Population Survey (CPS) were analyzed. This report describes the results of those analyses, which indicated that the prevalence of SHI among veterans was significantly greater than among nonveterans. Veterans were 30% more likely to have SHI than nonveterans after adjusting for age and current occupation, and veterans who served in the United States or overseas during September 2001-March 2010, the era of overseas contingency operations (including Operations Enduring Freedom and Iraqi Freedom), were four times more likely than nonveterans to have SHI. These findings suggest a need for increased emphasis on improving military hearing conservation programs (HCPs) and on hearing loss surveillance in military and veterans' health systems.

  19. A Search for Transnational Culture: An Ethnography of Students in an International School in Japan.

    ERIC Educational Resources Information Center

    Willis, David B.

    This anecdotal ethnography describes the student culture at Columbia Academy, an international school in Kobe, Japan. The paper begins by contrasting the affluence of Columbia Academy and its students with the relative austerity of a nearby Japanese middle school. The paper follows a typical day at Columbia, and describes the nationalities of the…

  20. Reclaiming Our Lives in the Wake of a Nuclear Plant Accident.

    PubMed

    Ando, R

    2016-04-01

    Ryoko Ando lives and works in Iwaki-shi, which is located in the coastal area of Fukushima Prefecture. On 11 March 2011, Iwaki was hit by the Great East Japan Earthquake and tsunami. Then the nuclear plant accident at Fukushima No. 1 nuclear power plant, also located in the coastal area of Fukushima Prefecture, added to the woes of Iwaki residents. Although Iwaki-shi is outside of the ‘restricted area’ set up by the government in the 20 km radius around the nuclear power plant, some municipalities in Iwaki-shi lie within the 30 km radius zone. The residents of Iwaki were naturally concerned about the effects of radioactive contamination. On top of these, they had to confront a wide range of issues, including confusion and miscommunication, reputation risk and infrastructural constraints due to the influx of residents from the ‘restricted area’.

  1. An attempt to apply the inelastic thermal spike model to surface modifications of CaF2 induced by highly charged ions: comparison to swift heavy ions effects and extension to some others material.

    PubMed

    Dufour, C; Khomrenkov, V; Wang, Y Y; Wang, Z G; Aumayr, F; Toulemonde, M

    2017-03-08

    Surface damage appears on materials irradiated by highly charged ions (HCI). Since a direct link has been found between surface damage created by HCI with the one created by swift heavy ions (SHI), the inelastic thermal spike model (i-TS model) developed to explain track creation resulting from the electron excitation induced by SHI can also be applied to describe the response of materials under HCI which transfers its potential energy to electrons of the target. An experimental description of the appearance of the hillock-like nanoscale protrusions induced by SHI at the surface of CaF 2 is presented in comparison with track formation in bulk which shows that the only parameter on which we can be confident is the electronic energy loss threshold. Track size and electronic energy loss threshold resulting from SHI irradiation of CaF 2 is described by the i-TS model in a 2D geometry. Based on this description the i-TS model is extended to three dimensions to describe the potential threshold of appearance of protrusions by HCI in CaF 2 and to other crystalline materials (LiF, crystalline SiO 2 , mica, LiNbO 3 , SrTiO 3 , ZnO, TiO 2 , HOPG). The strength of the electron-phonon coupling and the depth in which the potential energy is deposited near the surface combined with the energy necessary to melt the material defines the classification of the material sensitivity. As done for SHI, the band gap of the material may play an important role in the determination of the depth in which the potential energy is deposited. Moreover larger is the initial potential energy and larger is the depth in which it is deposited.

  2. The "critical limits for crystallinity" in nanoparticles of the elements: A combined thermodynamic and crystallographic critique

    NASA Astrophysics Data System (ADS)

    Pelegrina, J. L.; Guillermet, A. Fernández

    2018-03-01

    The theme of the present work is the procedure for evaluating the minimum size for the stability of a crystalline particle with respect to the same group of atoms but in the amorphous state. A key goal of the study is the critical analysis of an extensively quoted paper by F.G. Shi [J. Mater. Res. 9 (1994) 1307-1313], who presented a criterion for evaluating a "crystallinity distance" (h) through its relation with the "critical diameter" (dC) of a particle, i.e., the diameter below which no particles with the crystalline structure are expected to exist at finite temperatures. Key assumptions of Shi's model are a direct proportionality relation between h and dC , and a prescription for estimating h from crystallographic information. In the present work the accuracy of the Shi model is assessed with particular reference to nanoparticles of the elements. To this end, an alternative way to obtain h, that better realizes Shi's idea of this quantity as "the height of a monolayer of atoms on the bulk crystal surface", is explored. Moreover, a thermodynamic calculation of dC , which involves a description of the bulk- and the surface contributions to the crystalline/amorphous relative phase stability for nanoparticles, is performed. It is shown that the Shi equation does not account for the key features of the h vs. dC relation established in the current work. Consequently, it is concluded that the parameter h obtained only from information about the structure of the crystalline phase, does not provide an accurate route to estimate the quantity dC . In fact, a key result of the current study is that dC crucially depends on the relation between bulk- and surface contributions to the crystalline/amorphous relative thermodynamic stability.

  3. Identifying yield-optimizing environments for two cowpea breeding lines by manipulating photoperiod and harvest scenario

    NASA Technical Reports Server (NTRS)

    Ohler, T. A.; Mitchell, C. A.

    1996-01-01

    Photoperiod and harvest scenario of cowpea (Vigna unguiculata L. Walp) canopies were manipulated to optimize productivity for use in future controlled ecological life-support systems. Productivity was measured by edible yield rate (EYR:g m-2 day-1), shoot harvest index (SHI: g edible biomass [g total shoot dry weight]), and yield-efficiency rate (YER:g edible biomass m-2 day-1 per[g nonedible shoot dry weight]). Breeding lines 'IT84S-2246' (S-2246) and "IT82D-889' (D-889) were grown in a greenhouse under 8-, 12-, or 24-h photoperiods. S-2246 was short-day and D-889 was day-neutral for flowering. Under each photoperiod, cowpeas were harvested either for leaves only, seeds only, or leaves plus seeds (mixed harvest). Photoperiod did not affect EYR of either breeding line for any harvest scenario tested. Averaged over both breeding lines, seed harvest gave the highest EYR at 6.7 g m-2 day-1. The highest SHI (65%) and YER (94 mg m-2 day-1 g-1) were achieved for leaf-only harvest of D-889 under an 8-h photoperiod. For leaf-only harvest of S-2246, both SHI and YER increased with increasing photoperiod, but declined for seed-only and mixed harvests. However, photoperiod had no effect on SHI or YER for D-889 for any harvest scenario. A second experiment utilized the short-day cowpea breeding line 'IT89KD-288' (D-288) and the day-neutral breeding line 'IT87D-941-1' (D-941) to compare yield parameters using photoperiod extension under differing lamp types. This experiment confirmed the photoperiod responses of D-889 and S-2246 to a mixed-harvest scenario and indicated that daylength extension with higher irradiance from high pressure sodium lamps further suppressed EYR, SHI, and YER of the short-day breeding line D-288.

  4. Japan's High Schools.

    ERIC Educational Resources Information Center

    Rohlen, Thomas P.

    The author, an anthropologist, spent 14 months (1974-75) in the industrial port city of Kobe (Japan) observing a cross section of urban high schools, including Japan's most elite private school and a night vocational school plagued by absenteeism and delinquency. He reports on the character of the institutions and of the experience via…

  5. Experimental implementation of local adiabatic evolution algorithms by an NMR quantum information processor.

    PubMed

    Mitra, Avik; Ghosh, Arindam; Das, Ranabir; Patel, Apoorva; Kumar, Anil

    2005-12-01

    Quantum adiabatic algorithm is a method of solving computational problems by evolving the ground state of a slowly varying Hamiltonian. The technique uses evolution of the ground state of a slowly varying Hamiltonian to reach the required output state. In some cases, such as the adiabatic versions of Grover's search algorithm and Deutsch-Jozsa algorithm, applying the global adiabatic evolution yields a complexity similar to their classical algorithms. However, using the local adiabatic evolution, the algorithms given by J. Roland and N.J. Cerf for Grover's search [J. Roland, N.J. Cerf, Quantum search by local adiabatic evolution, Phys. Rev. A 65 (2002) 042308] and by Saurya Das, Randy Kobes, and Gabor Kunstatter for the Deutsch-Jozsa algorithm [S. Das, R. Kobes, G. Kunstatter, Adiabatic quantum computation and Deutsh's algorithm, Phys. Rev. A 65 (2002) 062301], yield a complexity of order N (where N=2(n) and n is the number of qubits). In this paper, we report the experimental implementation of these local adiabatic evolution algorithms on a 2-qubit quantum information processor, by Nuclear Magnetic Resonance.

  6. [Cooperation of medical and pharmaceutical sciences between private and national universities to educate professionals in the fields of drug development and rational pharmacotherapy].

    PubMed

    Iwakawa, Seigo

    2012-01-01

    Cooperation in education and research in medical and pharmaceutical sciences between Kobe Pharmaceutical University and Kobe University was started in 2008 for training professionals in drug development and rational pharmacotherapy. Initially, we started a two-year pharmacy residency program. Our pharmacy residents can attend lectures at our universities, and they also help pharmacist preceptors educate undergraduate pharmacy students in practical training. As curricula for cooperative education of pharmacy, nursing and medical students, we developed two new elective subjects (early exposure to clinical training for first year students and IPW (inter-professional work) seminar for fifth year pharmacy students) to learn about the roles of health care professionals in a medical team. Cooperative research between faculty members and graduate students is also in progress. For faculty and staff developments, invited lectures by clinical pharmacy and medical professors from the United States on the clinical education system in pharmacy and medicine in the United States have been held. This systematic cooperation will contribute to the promotion of a new curriculum for inter-professional education in the health-science fields.

  7. [Cost Analysis of Cochlear Implantation in Adults].

    PubMed

    Raths, S; Lenarz, T; Lesinski-Schiedat, A; Flessa, S

    2016-04-01

    The number of implantation of cochlear implants has steadily risen in recent years. Reasons for this are an extension of indication criteria, demographic change, increased quality of life needs and greater acceptance. The consequences are rising expenditure for statutory health insurance (SHI) for cochlear implantation. A detailed calculation of lifetime costs from SHI's perspective for postlingually deafened adolescents and adults is essential in estimating future cost developments. Calculations are based on accounting data from the Hannover Medical School. With regard to further life expectancy, average costs of preoperative diagnosis, surgery, rehabilitation, follow-ups, processor upgrades and electrical maintenance were discounted to their present value at age of implantation. There is an inverse relation between cost of unilateral cochlear implantation and age of initial implantation. From SHI's perspective, the intervention costs between 36,001 and 68,970 € ($ 42,504-$ 81,429). The largest cost components are initial implantation and processor upgrades. Compared to the UK the cost of cochlear implantation in Germany seems to be significantly lower. In particular the costs of, rehabilitation and maintenance in Germany cause only a small percentage of total costs. Also, the costs during the first year of treatment seem comparatively low. With regard to future spending of SHI due to implant innovations and associated extension of indication, increasing cost may be suspected. © Georg Thieme Verlag KG Stuttgart · New York.

  8. Analysing the impact of health-care system change in the EU member states--Germany.

    PubMed

    Wörz, Markus; Busse, Reinhard

    2005-09-01

    The core of the German health-care system is the statutory health insurance (SHI). Coverage of the SHI has remained fairly constant at about 90% whereas the rest of the population is insured for the most part with private health insurance. The primary goal of health-care reforms since the 1990s has been to contain the expenditure of the SHI. The primary measures to do this have been the introduction of budgets and a shift of expenditure towards private households mainly in the form of benefit exclusions and increased co-payments. So far these measures did not have a negative effect on broad outcome measures such as life expectancy, which continued to rise, and self-assessed health of the population, which remained stable in the period 1992--2002. Besides cost containment another leitmotif of reform have been attempts to increase competition both between sickness funds and providers of care. These two strands of reforms also affected the incentive structures for both insurers and providers in various ways which this article describes. The immediate future of health-care reform will concern the mode of financing of the SHI which centres on the question if contributions proportional to income shall be maintained or if there shall be a radical shift towards flat-rate health premiums. Copyright (c) 2005 John Wiley & Sons, Ltd.

  9. Individual boldness is linked to protective shell shape in aquatic snails.

    PubMed

    Ahlgren, Johan; Chapman, Ben B; Nilsson, P Anders; Brönmark, Christer

    2015-04-01

    The existence of consistent individual differences in behaviour ('animal personality') has been well documented in recent years. However, how such individual variation in behaviour is maintained over evolutionary time is an ongoing conundrum. A well-studied axis of animal personality is individual variation along a bold-shy continuum, where individuals differ consistently in their propensity to take risks. A predation-risk cost to boldness is often assumed, but also that the reproductive benefits associated with boldness lead to equivalent fitness outcomes between bold and shy individuals over a lifetime. However, an alternative or complementary explanation may be that bold individuals phenotypically compensate for their risky lifestyle to reduce predation costs, for instance by investing in more pronounced morphological defences. Here, we investigate the 'phenotypic compensation' hypothesis, i.e. that bold individuals exhibit more pronounced anti-predator defences than shy individuals, by relating shell shape in the aquatic snail Radix balthica to an index of individual boldness. Our analyses find a strong relationship between risk-taking propensity and shell shape in this species, with bolder individuals exhibiting a more defended shell shape than shy individuals. We suggest that this supports the 'phenotypic compensation' hypothesis and sheds light on a previously poorly studied mechanism to promote the maintenance of personality variation among animals. © 2015 The Author(s) Published by the Royal Society. All rights reserved.

  10. Should providers be allowed to extra bill for uncovered services? Debate, resolution, and sequel in Japan.

    PubMed

    Ikegami, Naoki

    2006-12-01

    Japan has managed to provide universal coverage at relatively low cost by containing prices and restricting the conditions for which services can be billed in the compulsory social health insurance (SHI) program. However, decline in Japan's economic growth ushered in new actors backed by the prime minister who proposed that the providers should be allowed to extra bill for services not covered by the SHI. In 2004 they took the strategy of drawing the attention of the public to areas where the rigidity of the current prohibition appeared to be unfair and ridiculous. They were opposed by the Ministry of Health, Labor, and Welfare and the Japan Medical Association, who strongly objected on the grounds of safety and equity. The compromise reached by the two ministers in charge led to a clarification of the services that are to be covered and of the process for extending coverage to new procedures and drugs. The prohibition on extra billing has remained essentially unchanged, but the momentum for deregulation has been lost. In 2005 an alternate proposal was made to contain SHI expenditures by introducing a global cap on health expenditures and increasing out-of-pocket payment. Although this proposal was not fully adopted, the gradual decline in SHI benefit levels could lead to a renewed move to allow extra billing.

  11. Identification of highly effective target genes for RNAi-mediated control of emerald ash borer, Agrilus planipennis.

    PubMed

    Rodrigues, Thais B; Duan, Jian J; Palli, Subba R; Rieske, Lynne K

    2018-03-22

    Recent study has shown that RNA interference (RNAi) is efficient in emerald ash borer (EAB), Agrilus planipennis, and that ingestion of double-stranded RNA (dsRNA) targeting specific genes causes gene silencing and mortality in neonates. Here, we report on the identification of highly effective target genes for RNAi-mediated control of EAB. We screened 13 candidate genes in neonate larvae and selected the most effective target genes for further investigation, including their effect on EAB adults and on a non-target organism, Tribolium castaneum. The two most efficient target genes selected, hsp (heat shock 70-kDa protein cognate 3) and shi (shibire), caused up to 90% mortality of larvae and adults. In EAB eggs, larvae, and adults, the hsp is expressed at higher levels when compared to that of shi. Ingestion of dsHSP and dsSHI caused mortality in both neonate larvae and adults. Administration of a mixture of both dsRNAs worked better than either dsRNA by itself. In contrast, injection of EAB.dsHSP and EAB.dsSHI did not cause mortality in T. castaneum. Thus, the two genes identified cause high mortality in the EAB with no apparent phenotype effects in a non-target organism, the red flour beetle, and could be used in RNAi-mediated control of this invasive pest.

  12. A System for Fast Navigation of Autonomous Vehicles

    DTIC Science & Technology

    1991-09-01

    AD-A243 523 4, jj A System for Fast Navigation of Autonomous Vehicles Sanjiv Singh, Dai Feng, Paul Keller, Gary Shaffer, Wen Fan Shi, Dong Hun Shin...FUNDING NUMBERS A System for Fast Navigation of Autonomous Vehicles 6. AUTHOR(S) S. Singh, D. Feng, P. Keller, G. Shaffer, W.F. Shi, D.H. Shin, J. West...common in the control of autonomous vehicles to establish the necessary kinematic models but to ignore an explicit representation of the vehicle dynamics

  13. KSC-02pd0422

    NASA Image and Video Library

    2002-04-04

    KENNEDY SPACE CENTER, FLA. - In the Multi-Payload Processing Facility, members of the STS-107 crew run tests on the Fast Reaction Experiments Enabling Science, Technology, Applications and Research (FREESTAR) experiments, part of the payload on their mission. A research mission, the primary payload is the first flight of the SHI Research Double Module (SHI/RDM), also known as SPACEHAB. The experiments range from material sciences to life sciences (many rats). STS-107 is scheduled to launch July 11, 2002

  14. JPRS Report, Soviet Union, USSR: Materials Science

    DTIC Science & Technology

    1988-08-24

    Interaction of Metal Melt With Carbon Fiber [T.A. Chernyshova , N.L. Bolotov, et al.; FIZIKA I KHIMIYA OBRABOTKI MATERIALOV, No 2, Mar-Apr 88] 6 Ferrous...manuscript received 27 Apr 87) pp 88-92 [Article by T.A. Chernyshova , N.L. Bolotov, L.I. Kobe- leva, M.P. Arsentyeva and K.P. Gurov, Moscow] [Abstract] An

  15. Draft Genome Sequence of Meiothermus ruber H328, Which Degrades Chicken Feathers, and Identification of Proteases and Peptidases Responsible for Degradation

    PubMed Central

    Inada, Shuhei

    2013-01-01

    Meiothermus ruber H328 was isolated from Arima Hot Springs, Kobe, Japan, as a moderate thermophile. It has a strong ability to degrade intact chicken feathers. The enzymatic mechanism of the strain for feather degradation is unclear. The draft genome suggests potent enzyme candidates for degradation of keratin, a hard-to-degrade protein found in feathers. PMID:23640376

  16. A Chrysanthemum in the Garden: A Christian Kindergarten in the Empire of Japan

    ERIC Educational Resources Information Center

    Nishida, Yukiyo

    2015-01-01

    This is a study of the contribution of Christian missionaries to kindergarten education in the Empire of Japan. The study concerns an American Missionary woman, Annie L. Howe (1852-1943) and her kindergarten in Kobe, Japan. Annie L. Howe had a great impact on the history of early childhood education and is still remembered as the "Mother of…

  17. Value Orientation Among International School Students.

    ERIC Educational Resources Information Center

    Willis, David B.

    This case study of 215 high school students in Columbia Academy, an international school in Kobe, Japan, was conducted from 1980 to 1985 to examine the values students hold in relation to their demographic characteristics. The study, written by a faculty member of this school who also served on the Educational Policy Committee of the Board of…

  18. Sleeping money: investigating the huge surpluses of social health insurance in China.

    PubMed

    Liu, JunQiang; Chen, Tao

    2013-12-01

    The spreading of social health insurance (SHI) worldwide poses challenges for fledging public administrators. Inefficiency, misuse and even corruption threaten the stewardship of those newly established health funds. This article examines a tricky situation faced by China's largest SHI program: the basic health insurance (BHI) scheme for urban employees. BHI accumulated a 406 billion yuan surplus by 2009, although the reimbursement level was still low. Using a provincial level panel database, we find that the huge BHI surpluses are related to the (temporarily) decreasing dependency ratio, the steady growth of average wages, the extension of BHI coverage, and progress in social insurance agency building. The financial situations of local governments and risk pooling level also matter. Besides, medical savings accounts result in about one third of BHI surpluses. Although these findings are not causal, lessons drawn from this study can help to improve the governance and performance of SHI programs in developing countries.

  19. Electronic and atomic kinetics in solids irradiated with free-electron lasers or swift-heavy ions

    NASA Astrophysics Data System (ADS)

    Medvedev, N.; Volkov, A. E.; Ziaja, B.

    2015-12-01

    In this brief review we discuss the transient processes in solids under irradiation with femtosecond X-ray free-electron-laser (FEL) pulses and swift-heavy ions (SHI). Both kinds of irradiation produce highly excited electrons in a target on extremely short timescales. Transfer of the excess electronic energy into the lattice may lead to observable target modifications such as phase transitions and damage formation. Transient kinetics of material excitation and relaxation under FEL or SHI irradiation are comparatively discussed. The same origin for the electronic and atomic relaxation in both cases is demonstrated. Differences in these kinetics introduced by the geometrical effects (μm-size of a laser spot vs nm-size of an ion track) and initial irradiation (photoabsorption vs an ion impact) are analyzed. The basic mechanisms of electron transport and electron-lattice coupling are addressed. Appropriate models and their limitations are presented. Possibilities of thermal and nonthermal melting of materials under FEL and SHI irradiation are discussed.

  20. Production and Application of a Soluble Hydrogenase from Pyrococcus furiosus

    PubMed Central

    Wu, Chang-Hao; McTernan, Patrick M.; Walter, Mary E.; Adams, Michael W. W.

    2015-01-01

    Hydrogen gas is a potential renewable alternative energy carrier that could be used in the future to help supplement humanity's growing energy needs. Unfortunately, current industrial methods for hydrogen production are expensive or environmentally unfriendly. In recent years research has focused on biological mechanisms for hydrogen production and specifically on hydrogenases, the enzyme responsible for catalyzing the reduction of protons to generate hydrogen. In particular, a better understanding of this enzyme might allow us to generate hydrogen that does not use expensive metals, such as platinum, as catalysts. The soluble hydrogenase I (SHI) from the hyperthermophile Pyrococcus furiosus, a member of the euryarchaeota, has been studied extensively and used in various biotechnological applications. This review summarizes the strategies used in engineering and characterizing three different forms of SHI and the properties of the recombinant enzymes. SHI has also been used in in vitro systems for hydrogen production and NADPH generation and these systems are also discussed. PMID:26543406

  1. Production and Application of a Soluble Hydrogenase from Pyrococcus furiosus

    DOE PAGES

    Wu, Chang-Hao; McTernan, Patrick M.; Walter, Mary E.; ...

    2015-01-01

    Hydrogen gas is a potential renewable alternative energy carrier that could be used in the future to help supplement humanity’s growing energy needs. Unfortunately, current industrial methods for hydrogen production are expensive or environmentally unfriendly. In recent years research has focused on biological mechanisms for hydrogen production and specifically on hydrogenases, the enzyme responsible for catalyzing the reduction of protons to generate hydrogen. In particular, a better understanding of this enzyme might allow us to generate hydrogen that does not use expensive metals, such as platinum, as catalysts. The soluble hydrogenase I (SHI) from the hyperthermophile Pyrococcus furiosus , amore » member of the euryarchaeota, has been studied extensively and used in various biotechnological applications. This review summarizes the strategies used in engineering and characterizing three different forms of SHI and the properties of the recombinant enzymes. SHI has also been used in in vitro systems for hydrogen production and NADPH generation and these systems are also discussed.« less

  2. Skeletal ontogeny of the vertebral column and of the fins in shi drum Umbrina cirrosa (Teleostei: Perciformes: Sciaenidae), a new candidate species for aquaculture.

    PubMed

    Neofytou, M; Sfakianakis, D G; Koumoundouros, G; Mylonas, C C; Kentouri, M

    2017-09-01

    The osteological development of the vertebral column and fins in shi drum Umbrina cirrosa was studied in order to improve knowledge for its introduction in Mediterranean aquaculture. The osteological development was studied in 171 individuals, of total length (L T ) from 2·7 to 30·2 mm that were reared under the mesocosm technique. Vertebral ontogeny starts at 3·4 and 4·0 mm L T , with the formation of the first cartilaginous neural and haemal arches, and spines, respectively, and is completed with the full attainment of epicentrals (12·5 mm L T ). The formation of vertebral centra occurs between 4·1 and 7·4 mm L T . Pectoral supports are the first fin elements to develop (3·0 mm L T ), followed by those of the caudal fin (3·8 mm L T ), pelvic fin (3·9 mm L T ) and finally by those of the dorsal and anal fins (4·5 mm L T ). The caudal fin is the first to develop fin rays and attain the full count of principal fin rays (4·5-6·8 mm L T ), but the last to be fully completed with the formation of procurrent fin rays (6·9-17·5 mm L T ). The next fins starting to present rays are the dorsal (5·3 mm L T ) and the pectoral fins (5·6 mm L T ), while the anal and pelvic fins are the last (5·7 mm L T ). Following the caudal principal fin rays (6·8 mm L T ), the dorsal, anal (6·9 mm L T ), pelvic (7·4 mm L T ) and pectoral fins (9·8 mm L T ) are the next with fully completed ray counts. Aggregation of qualitative changes, such as the appearance of cartilages, the beginning and the complement of the ossification process and the full complement of elements in U. cirrosa were measured as cumulative frequency counts. These measurements reveal three ontogenetic intervals: one very developmentally active period during early life stages (from 3 to 5·9 mm L T ), a second slower developmental period (from 6·0 to 8·9 mm L T ) and finally a period of ontogeny more focused on structure refinement up to metamorphosis and settlement (>9·0 mm L T ). © 2017 The

  3. The SHiP experiment at CERN

    NASA Astrophysics Data System (ADS)

    De Lellis, G.; SHiP Collaboration

    2017-04-01

    The discovery of the Higgs boson has fully confirmed the Standard Model of particles and fields. Nevertheless, there are still fundamental phenomena, like the existence of dark matter and the baryon asymmetry of the Universe, which deserve an explanation that could come from the discovery of new particles. Searches for new physics with accelerators are performed at the LHC, looking for high massive particles coupled to matter with ordinary strength. A new experiment at CERN meant to search for very weakly coupled particles in the few GeV mass domain has been recently proposed. The existence of such particles, foreseen in different theoretical models beyond the Standard Model, is largely unexplored. A beam dump facility using high intensity 400 GeV protons is a copious source of such unknown particles in the GeV mass range. The beam dump is also a copious source of neutrinos and in particular it is an ideal source of tau neutrinos, the less known particle in the Standard Model. Indeed, tau anti-neutrinos have not been directly observed so far. We report the physics potential of such an experiment.

  4. Let's Not Be Shy about Marketing.

    ERIC Educational Resources Information Center

    Trachtenberg, Stephen Joel

    1984-01-01

    Attitudes about college marketing have hindered its progress. It is an informative process with strong feedback, including such elements as information gathering, travel, development of a marketing or public relations plan, organizational communication, institutional adaptation to the current market, and administrator input. (MSE)

  5. Ion beam synthesis of Au nanoparticles embedded nano-composite glass

    NASA Astrophysics Data System (ADS)

    Varma, Ranjana S.; Kothari, D. C.; Kumar, Ravi; Kumar, P.; Santra, S. S.; Thomas, R. G.

    2013-02-01

    Ion beam mixing using low energy (LE) ion beams (100 keV Ar+) has been used to form Au nanoparticles in the near-surface region of fused silica glasses. Effect of swift heavy ion (SHI) irradiation (with 120 MeV Ag9+), on the nanoparticles has been studied. Diffusion length of Au after the beam mixing and the irradiation has been found to be 14nm. SHI irradiation causes the increase in the size of the nanoparticles, reduction in size-distribution and increase in number density.

  6. KSC01PD1861

    NASA Image and Video Library

    2001-12-10

    KENNEDY SPACE CENTER, FLA. -- At SPACEHAB in Cape Canaveral, Fla., STS-107 Mission Specialists Ilan Ramon of Israel and Laurel Clark check out the equipment for the mission. STS-107 is a research mission, and the primary payload is the first flight of the SHI Research Double Module (SHI/RDM). The experiments range from material sciences to life sciences (many rats). Among the experiments is a Hitchhiker carrier system, modular and expandable in accordance with payload requirements. STS-107 is scheduled to launch in June 2002

  7. KSC-02pd1763

    NASA Image and Video Library

    2002-11-20

    KENNEDY SPACE CENTER, FLA. -- Space Shuttle Columbia is being moved to the Vehicle Assembly Building where processing will continue for the flight of mission STS-107. Launch is now targeted for no earlier than Jan. 16, 2003. The STS-107 mission will be dedicated to microgravity research. The payloads include the Hitchhiker Bridge, a carrier for the Fast Reaction Experiments Enabling Science, Technology, Applications and Research (FREESTAR) incorporating eight high priority secondary attached Shuttle experiments, and the SHI Research Double Module (SHI/RDM), also known as SPACEHAB.

  8. [Market Concentration in the Statutory Health Insurance of Germany since the Introduction of Free Choice of Sickness Funds].

    PubMed

    Götze, R

    2016-11-01

    Background: The expansion of trust law to the German statutory health insurance (SHI) and the declining numbers of sickness funds suggest a strong concentration process in the German SHI market. The paper examines the level and development of market concentration since the introduction of the free choice of sickness funds in 1996. Data: The study is based on a dataset containing information on membership, contribution rate, openness, area of activity and legal successor for all sickness funds in the period from 1996 to 2013. Methods: Market concentration is measured by the concentration rate (cumulative market share of the largest market participants) and the Herfindahl-Hirschman index (HHI). In addition, the change in the HHI is also disaggregated into 3 factors: opening, switching and fusion of sickness funds. Results: Concentration rate and HHI decreased significantly between 1996 and 2008 due to opening of former closed sickness funds and a switching behaviour from large to small funds. The SHI Competition Enhancement Act of 2007 led to a turnaround. The reform permitted cross-type mergers and introduced a completely new system of budget allocation with the central health fund. The latter put an end to the growing membership of small funds due to adverse selection processes. As a result, market concentration in the German SHI rises. Although recent mega-mergers were uncritical for nationwide competition, the study already indicates the risk of market dominance on the regional level. © Georg Thieme Verlag KG Stuttgart · New York.

  9. Healthcare financing reform in Latvia: switching from social health insurance to NHS and back?

    PubMed

    Mitenbergs, Uldis; Brigis, Girts; Quentin, Wilm

    2014-11-01

    In the 1990s, Latvia aimed at introducing Social Health Insurance (SHI) but later changed to a National Health Service (NHS) type system. The NHS is financed from general taxation, provides coverage to the entire population, and pays for a basic service package purchased from independent public and private providers. In November 2013, the Cabinet of Ministers passed a draft Healthcare Financing Law, aiming at increasing public expenditures on health by introducing Compulsory Health Insurance (CHI) and linking entitlement to health services to the payment of income tax. Opponents of the reform argue that linking entitlement to health services to the payment of income tax does not have the potential to increase public expenditures on health but that it can contribute to compromising universal coverage and access to health services of certain population groups. In view of strong opposition, it is unlikely that the law will be adopted before parliamentary elections in October 2014. Nevertheless, the discussion around the law is interesting because of three main reasons: (1) it can illustrate why the concept of SHI remains attractive - not only for Latvia but also for other countries, (2) it shows that a change from NHS to SHI does not imply major institutional reforms, and (3) it demonstrates the potential problems of introducing SHI, i.e. of linking entitlement to health services to the payment of contributions. Copyright © 2014 The Authors. Published by Elsevier Ireland Ltd.. All rights reserved.

  10. Cost effectiveness of full coverage of the medical management of smoking cessation in France.

    PubMed

    Chevreul, Karine; Cadier, Benjamin; Durand-Zaleski, Isabelle; Chan, Elis; Thomas, Daniel

    2014-05-01

    To estimate the incremental cost effectiveness of full coverage of the medical management of smoking cessation from the perspective of statutory health insurance (SHI) in France. Cost-effectiveness analysis based on a Markov state-transition decision analytic model was used to compare full SHI coverage of smoking cessation and actual coverage based on an annual €50 lump sum per insured person among current French smokers aged 15-75 years. We used a scenario approach to take into account the many different behaviours of smokers and the likely variability of SHI policy choices in terms of participation rate and number and frequency of attempts covered. Drug treatments for smoking cessation combined with six medical consultations including individual counselling. The cost effectiveness of full coverage was expressed by the incremental cost-effectiveness ratio (ICER) in 2009 euros per life-year gained (LYG) at the lifetime horizon. The cost effectiveness per LYG for smokers ranged from €1786 to €2012, with an average value of €1911. The minimum value was very close to the maximum value with a difference of only €226. The cost-effectiveness ratio was only minimally sensitive to the participation rate, the number of attempts covered and the cessation rate. Compared to other health measures in primary and secondary prevention of cardiovascular disease already covered by SHI, full coverage of smoking cessation is the most cost-effective approach.

  11. Comparison of fundamental, second harmonic, and superharmonic imaging: a simulation study.

    PubMed

    van Neer, Paul L M J; Danilouchkine, Mikhail G; Verweij, Martin D; Demi, Libertario; Voormolen, Marco M; van der Steen, Anton F W; de Jong, Nico

    2011-11-01

    In medical ultrasound, fundamental imaging (FI) uses the reflected echoes from the same spectral band as that of the emitted pulse. The transmission frequency determines the trade-off between penetration depth and spatial resolution. Tissue harmonic imaging (THI) employs the second harmonic of the emitted frequency band to construct images. Recently, superharmonic imaging (SHI) has been introduced, which uses the third to the fifth (super) harmonics. The harmonic level is determined by two competing phenomena: nonlinear propagation and frequency dependent attenuation. Thus, the transmission frequency yielding the optimal trade-off between the spatial resolution and the penetration depth differs for THI and SHI. This paper quantitatively compares the concepts of fundamental, second harmonic, and superharmonic echocardiography at their optimal transmission frequencies. Forward propagation is modeled using a 3D-KZK implementation and the iterative nonlinear contrast source (INCS) method. Backpropagation is assumed to be linear. Results show that the fundamental lateral beamwidth is the narrowest at focus, while the superharmonic one is narrower outside the focus. The lateral superharmonic roll-off exceeds the fundamental and second harmonic roll-off. Also, the axial resolution of SHI exceeds that of FI and THI. The far-field pulse-echo superharmonic pressure is lower than that of the fundamental and second harmonic. SHI appears suited for echocardiography and is expected to improve its image quality at the cost of a slight reduction in depth-of-field.

  12. KSC-02pd1198

    NASA Image and Video Library

    2002-08-19

    KENNEDY SPACE CENTER, FLA. -- Only the nose and tail of Columbia are visible as it sits inside an protective tent used to keep out moisture. The orbiter is next scheduled to fly on mission STS-107 no earlier than Nov. 29. STS-107 is a research mission. The payload includes the Hitchhiker Bridge, a carrier for the Fast Reaction Experiments Enabling Science, Technology, Applications and Research (FREESTAR) that incorporates eight high priority secondary attached shuttle experiments, plus the SHI Research Double Module (SHI/RDM), also known as SPACEHAB.

  13. CTC Sentinel. Volume 3, Issue 7, July 2010

    DTIC Science & Technology

    2010-07-01

    reports say they are free to operate. It has been reported that these Iran-based al-Qa`ida cells played a support role in the al-Qa`ida attacks on...how al-Qa`ida views Iran and the Shi`a. Al-Zarqawi began by saying that the Shi`a are “an insurmountable obstacle, a lurking snake, a crafty and...He even quoted a European specialist as saying that if the “Safavids had not existed, we in Europe would be reading the Quran just as the Algerians

  14. The [NiFe]-Hydrogenase of Pyrococcus furiosus Exhibits a New Type of Oxygen Tolerance.

    PubMed

    Kwan, Patrick; McIntosh, Chelsea L; Jennings, David P; Hopkins, R Chris; Chandrayan, Sanjeev K; Wu, Chang-Hao; Adams, Michael W W; Jones, Anne K

    2015-10-28

    We report the first direct electrochemical characterization of the impact of oxygen on the hydrogen oxidation activity of an oxygen-tolerant, group 3, soluble [NiFe]-hydrogenase: hydrogenase I from Pyrococcus furiosus (PfSHI), which grows optimally near 100 °C. Chronoamperometric experiments were used to probe the sensitivity of PfSHI hydrogen oxidation activity to both brief and prolonged exposure to oxygen. For experiments between 15 and 80 °C, following short (<200 s) exposure to 14 μM O2 under oxidizing conditions, PfSHI always maintains some fraction of its initial hydrogen oxidation activity; i.e., it is oxygen-tolerant. Reactivation experiments show that two inactive states are formed by interaction with oxygen and both can be quickly (<150 s) reactivated. Analogous experiments, in which the interval of oxygen exposure is extended to 900 s, reveal that the response is highly temperature-dependent. At 25 °C, under sustained 1% O2/ 99% H2 exposure, the H2oxidation activity drops nearly to zero. However, at 80 °C, up to 32% of the enzyme's oxidation activity is retained. Reactivation of PfSHI following sustained exposure to oxygen occurs on a much longer time scale (tens of minutes), suggesting that a third inactive species predominates under these conditions. These results stand in contrast to the properties of oxygen-tolerant, group 1 [NiFe]-hydrogenases, which form a single state upon reaction with oxygen, and we propose that this new type of hydrogenase should be referred to as oxygen-resilient. Furthermore, PfSHI, like other group 3 [NiFe]-hydrogenases, does not possess the proximal [4Fe3S] cluster associated with the oxygen tolerance of some group 1 enzymes. Thus, a new mechanism is necessary to explain the observed oxygen tolerance in soluble, group 3 [NiFe]-hydrogenases, and we present a model integrating both electrochemical and spectroscopic results to define the relationships of these inactive states.

  15. Implementation of CDC's School Health Index in 3 midwest middle schools: motivation for change.

    PubMed

    Sherwood-Puzzello, Catherine M; Miller, Michelle; Lohrmann, David; Gregory, Patricia

    2007-08-01

    The Centers for Disease Control and Prevention's School Health Index (SHI), a guide for completing a coordinated school-based program needs assessment relative to healthy eating, physical activity, a tobacco-free lifestyle, and prevention of other health risk behaviors and conditions, was used to assess current programming at 3 midwestern middle schools. Employing somewhat different procedures, data were collected from focus groups comprising school administrators, teachers, parents, community members, and students. Participants responded to SHI module questions and provided comments based on their perceptions. Both quantitative and qualitative data were recorded for each module, after which participants answered 3 planning questions intended to guide prioritization of actions to improve policies and programs based on importance, cost, time, commitment, and feasibility. Each school developed recommendations and strategies based on highest priority needs related to community involvement, professional development, health screenings, and health education materials in classrooms. The experience of completing the SHI in 3 different schools provided important insights about the data collection process as well as assessment results that have implications for the design and implementation of prevention programs.

  16. Security Enhanced User Authentication Protocol for Wireless Sensor Networks Using Elliptic Curves Cryptography

    PubMed Central

    Choi, Younsung; Lee, Donghoon; Kim, Jiye; Jung, Jaewook; Nam, Junghyun; Won, Dongho

    2014-01-01

    Wireless sensor networks (WSNs) consist of sensors, gateways and users. Sensors are widely distributed to monitor various conditions, such as temperature, sound, speed and pressure but they have limited computational ability and energy. To reduce the resource use of sensors and enhance the security of WSNs, various user authentication protocols have been proposed. In 2011, Yeh et al. first proposed a user authentication protocol based on elliptic curve cryptography (ECC) for WSNs. However, it turned out that Yeh et al.'s protocol does not provide mutual authentication, perfect forward secrecy, and key agreement between the user and sensor. Later in 2013, Shi et al. proposed a new user authentication protocol that improves both security and efficiency of Yeh et al.'s protocol. However, Shi et al.'s improvement introduces other security weaknesses. In this paper, we show that Shi et al.'s improved protocol is vulnerable to session key attack, stolen smart card attack, and sensor energy exhausting attack. In addition, we propose a new, security-enhanced user authentication protocol using ECC for WSNs. PMID:24919012

  17. Security enhanced user authentication protocol for wireless sensor networks using elliptic curves cryptography.

    PubMed

    Choi, Younsung; Lee, Donghoon; Kim, Jiye; Jung, Jaewook; Nam, Junghyun; Won, Dongho

    2014-06-10

    Wireless sensor networks (WSNs) consist of sensors, gateways and users. Sensors are widely distributed to monitor various conditions, such as temperature, sound, speed and pressure but they have limited computational ability and energy. To reduce the resource use of sensors and enhance the security of WSNs, various user authentication protocols have been proposed. In 2011, Yeh et al. first proposed a user authentication protocol based on elliptic curve cryptography (ECC) for WSNs. However, it turned out that Yeh et al.'s protocol does not provide mutual authentication, perfect forward secrecy, and key agreement between the user and sensor. Later in 2013, Shi et al. proposed a new user authentication protocol that improves both security and efficiency of Yeh et al.'s protocol. However, Shi et al.'s improvement introduces other security weaknesses. In this paper, we show that Shi et al.'s improved protocol is vulnerable to session key attack, stolen smart card attack, and sensor energy exhausting attack. In addition, we propose a new, security-enhanced user authentication protocol using ECC for WSNs.

  18. Plant-water relationships and growth of black walnut in a walnut-forage multicropping regime

    Treesearch

    Daniel C. Dey; M. R. Conway; H. E. Garrett; T. S. Hinckley; G. S. Cox

    1987-01-01

    Eastern black walnut seedlings were planted on a 1.5 ? 1.5m spacing in the spring of 1976 and irrigated throughout the growing season. During the spring of 1977, forage plots consisting of Kentucky 31 tall fescue, orchard grass, or Kobe lespedeza measuring 1 m wide and 10.2 m long and centered on a row of trees, were established with and without irrigation. Soil-water...

  19. The Healthy Class of 2010: Utilization of the School Health Index to Build Collaboration Between a University and an Urban School District

    PubMed Central

    Fryer, Craig S.; Reed, Ernestine A.; Thomas, Stephen B.

    2014-01-01

    BACKGROUND Insufficient attention has been paid to the process of conducting the Centers for Disease Control and Prevention’s School Health Index (SHI) to promote collaboration between universities and urban school districts when developing adolescent health promotion initiatives. This article provides an overview of the real world contextual challenges and opportunities this type of collaboration can pose. METHODS The SHI and selected collaboration principles were used to facilitate partnership and increase stakeholder buy-in, which led to developing and implementing an eight year health promotion campaign, The Healthy Class of 2010 (HC 2010). RESULTS The focus on planning brought together key stakeholders and allowed for HC 2010 programming to take place despite the competing demands on the schools. The SHI allowed for input from stakeholders to develop campaign activities and inform school- and district-wide policy. Universities and school districts desiring to develop and implement school-based, adolescent health promotion programs should: 1) identify the hierarchical structure of the school district; 2) establish credibility for the program and the university staff; 3) emphasize the benefits to all partners; 4) maintain a cooperative partnership with teachers and administrators; 5) appreciate the need for planning; and, 6) provide as many resources as possible to on an already overburdened school system. CONCLUSIONS Promoting healthy behaviors among students is an important part of the fundamental mission of schools. HC 2010 underscored the significance of collaboration using the SHI in the development and implementation of this health promotion campaign with input from students, teachers, administrators and university partners. PMID:22070509

  20. Understanding the unique experiences, perspectives and sexual and reproductive health needs of very young adolescents: Somali refugees in Ethiopia.

    PubMed

    Ortiz-Echevarria, Luis; Greeley, Meghan; Bawoke, Tenaw; Zimmerman, Linnea; Robinson, Courtland; Schlecht, Jennifer

    2017-01-01

    Kobe Refugee camp hosts roughly 39,000 refugees displaced from Somalia during the 2011-2012 Horn of Africa Crisis. Sexual and reproductive health, as with the greater issues of health and well-being for adolescents displaced from this crisis remain largely unknown and neglected. In 2013, the Women's Refugee Commission, Johns Hopkins University, and International Medical Corps in Ethiopia, implemented qualitative and quantitative research to explore the factors and risks that impact the health of very young adolescents (VYAs), those 10-14 years of age, in this setting. This paper presents findings from the qualitative effort. Focus group discussions (FGD), incorporating community mapping and photo elicitation activities, were conducted with 10-12 and 13-14 year-olds to obtain information about their own perspectives, experiences and values. FGDs were also implemented with 15-16 year-olds and adults, to consider their perspectives on the sexual and reproductive health needs and risks of VYAs. This research identified several factors that were found to influence the health and well-being of VYAs in Kobe refugee camp, including newfound access to education and security, combined with gender divisions and parental communication around early SRH and puberty that remained intact from traditional Somali culture. Girls were found to face an additional risk of child marriage and early pregnancy exacerbated since displacement, which significantly limited their ability to access education and achieve future aspirations. Findings from this study could help to inform future programs in Kobe and similar contexts involving long-term displacement from conflict, focusing on the health and development needs of VYAs. Future programs should consider the determinants of positive VYA health and development, including access to education, gender equity, and safety.By better understanding the unique experiences, perspectives and needs of VYAs, practitioners, policy makers and donors can

  1. KSC-03pd0105

    NASA Image and Video Library

    2003-01-16

    KENNEDY SPACE CENTER, FLA. - STS-107 Payload Commander Michael Anderson is happy to being suiting up for launch on mission STS-107. The mission is devoted to research and will include more than 80 experiments that will study Earth and space science, advanced technology development, and astronaut health and safety. The payload on Space Shuttle Columbia includes FREESTAR (Fast Reaction Experiments Enabling Science, Technology, Applications and Research) and the SHI Research Double Module (SHI/RDM), known as SPACEHAB. Experiments on the module range from material sciences to life sciences. Liftoff is scheduled for 10:39 a.m. EST.

  2. KSC-02pd0758

    NASA Image and Video Library

    2002-05-24

    KENNEDY SPACE CENTER, FLA. -- Dressed in a bunny suit, STS-107 Payload Specialist Ilan Ramon, who is with the Israeli Space Agency, reviews data in Columbia's payload bay for Fast Reaction Experiments Enabling Science, Technology, Applications and Research (FREESTAR) experiments for the mission. FREESTAR comprises Mediterranean Israeli Dust, Solar Constant, Shuttle Ozone Limb Sounding, Critical Viscosity of Xenon, Low Power, and Space Experimental Module experiments. Another payload is the SHI Research Double Module (SHI/RDM), also known as SPACEHAB. The experiments range from material sciences to life sciences. STS-107 is scheduled to launch July 11, 2002

  3. Plant-water relationships and growth of black walnut in a walnut-forage multicropping regime

    Treesearch

    D. Dey; M.R. Conway; H.E. Garrett; T.S. Hinckley; G.S. Cox

    1987-01-01

    Eastern black walnut seedlings were planted on a 1.5 x 1.5m spacing in the spring of 1976 and irrigated throughout the growing season. During the spring of 1977, forage plots consisting of Kentucky 31 tall fescue, orchard grass, or Kobe lespedeza measuring 1 m wide and 10.2 m long and centered on a row of trees, were established with and without irrigation. Soil-water...

  4. NATO-Advances Study Institute, Diamond and Diamond-Like Films and Coatings, Held in Il Ciocco, Castelvecchio Pascoli, Italy on July 22-August 3, 1990

    DTIC Science & Technology

    1990-08-03

    Coimbra P-3000 Coimbra, Portugal Phone: FAX: 351-39-29158 Dr. Jean - Jacques Dubray Ccrarnic Science & Engineering Department 217, Steidle Building...Corso Duca degli Abruzzi, 24 10129 Torino, Italy Phone: 39-11-3358240 FAX: 39-11-5567399 Ms. Filomena Pinto DosSantos Physics Department University of...474223 Mr. Jean Mercier IEPES BP 166 38092 Grenoble Cedex, France Phone: 33-76-881183 FAX: 33-76-887988 Dr. Koichi Miyata Kobe Steel Research

  5. [Brachytherapy for Prostate Cancer: Potentials and Limitations of Social Health Insurance Data for Benefit Assessment].

    PubMed

    Horenkamp-Sonntag, D; Linder, R; Engel, S; Verheyen, F

    2016-05-01

    Due to the insufficient data base the Federal Joint Committee (G-BA) had in 2009 after 7 years of deliberation decided to initiate consultation regarding ambulatory brachytherapy for localised prostate cancer for 10 years from social health insurance (SHI) benefits. The aim is to gain more findings by means of comparative studies. Based on the non-availability of clinical primary data of a methodologically acceptable level, it was analysed to what extent secondary data of the SHI may be used in order to arrive at valid conclusions for benefit aspects. As base approx. 8 million insured of TK with their data of cost reimbursement between 2006 and 2011 were considered. In SHI secondary data no clinical information regarding tumour stage and other prognostic factors are available. Therefore, a novel method with therapy-specific multisectoral inclusion and exclusion criteria, respectively, was developed in order to differentiate between localised and advanced tumours of the prostate. Overall survival, relapse-free survival, event-free survival and side-effects associated to prostate cancer were analysed. Out of 87 822 insured persons with the diagnosis prostate cancer, 795 with PBT, 10 936 with RP and 1 925 with EBRT were investigated in detail. The 4-year event-free survival rate was 73% for RP, 77% for PBT and 71% for EBRT. Many prostate cancer-specific side effects appeared already before intervention. Side effects of the intestinal tract (23.8%) and sexual impairments (26.5%) were more frequent for EBRT than for RP (17.1%/14.8%) and PBT (16.4%/13.2%). By means of SHI secondary data and adequate operationalisation important findings regarding relevant aspects of prostate cancer in healthcare research can be generated. However, these hold methodological limitations and are not suited to draw valid conclusions for benefit assessment. Based solely on SHI routine data valid statements regarding comparative benefit assessment are limited. Limitations could be

  6. Force Criterion Prediction of Damage for Carbon/Epoxy Composite Panels Impacted by High Velocity Ice

    NASA Astrophysics Data System (ADS)

    Rhymer, Jennifer D.

    The use of advanced fiber-reinforced polymer matrix composites in load-bearing aircraft structures is increasing, as evident by the various composites-intensive transport aircraft presently under development. A major impact source of concern for these structures is hail ice, which affects design and skin-sizing (skin thickness determination) at various locations of the aircraft. Impacts onto composite structures often cause internal damage that is not visually detectable due to the high strength and resiliency of the composite material (unlike impacts onto metallic structures). This internal damage and its effect on the performance of the structure are of great concern to the aircraft industry. The prediction of damage in composite structures due to SHI impact has been accomplished via experimental work, explicit dynamic nonlinear finite element analysis (FEA) and the definition of design oriented relationships. Experiments established the critical threshold and corresponding analysis provided contact force results not readily measurable in high velocity SHI impact experiments. The design oriented relationships summarize the FEA results and experimental database into contact force estimation curves that can be easily applied for damage prediction. Failure thresholds were established for the experimental conditions (panel thickness ranging from 1.56 to 4.66 mm and ice diameters from 38.1 to 61.0 mm). Additionally, the observations made by high-speed video during the impact event, and ultrasonic C-scan post-impact, showed how the ice failed during impact and the overall shape and location of the panel damage. Through analysis, the critical force, the force level where damage occurs above but not below, of a SHI impact onto the panel was found to be dependent only on the target structure. However, the peak force generated during impact was dependent on both the projectile and target. Design-oriented curves were generated allowing the prediction of the allowable

  7. Lifetime Self-Harm Behaviors Are Not More Prevalent in Bariatric Surgery Candidates than in Community Controls with Obesity.

    PubMed

    Müller, Astrid; Claes, Laurence; Smits, Dirk; Schag, Kathrin; de Zwaan, Martina

    2018-01-01

    The study aimed at investigating the lifetime prevalence of 22 self-harm behaviors in bariatric surgery candidates (pre-bariatric surgery group; PSG) compared to community controls with obesity (obese community group; OCG). The Self-Harm Inventory (SHI) was administered to the PSG (n = 139, BMI ≥ 35 kg/m2) and to the OCG (n = 122, BMI ≥ 35 kg/m2). Group comparison of cumulative SHI scores indicated a trend towards less endorsed SHI items in the PSG compared to the OCG (medianPSG = 1.00, IQRPSG = 2.00, medianOCG = 1.00, IQROCG = 2.25, U = 7.241, p = 0.033, η2 = 0.02). No significant group differences were found with regard to the rate of suicide attempts (12.4% vs. 9.4% for OCG vs. PSG). At least one type of lifetime self-harm behavior was admitted by 51.8% of the PSG and 63.9% of the OCG (χ2(1) = 3.91, p = 0.048). The results of logistic regressions using Firth's bias reduction method with at least one SHI item endorsed as dependent variable, group as categorical predictor (PSG as baseline), and age or BMI or PHQ-4 as continuous control variable indicated that only PHQ-4 had a positive effect on the odds ratio. The results suggest that self-harm (including suicidal attempts) is not more prevalent in bariatric surgery candidates than in community control participants with obesity. Further studies are needed to investigate self-harm in bariatric surgery patients, prior and following surgery, compared to non-operated patients with obesity. © 2018 The Author(s) Published by S. Karger GmbH, Freiburg.

  8. Can personality predict individual differences in brook trout spatial learning ability?

    USGS Publications Warehouse

    White, S.L.; Wagner, Tyler; Gowan, C.; Braithwaite, V.A.

    2017-01-01

    While differences in individual personality are common in animal populations, understanding the ecological significance of variation has not yet been resolved. Evidence suggests that personality may influence learning and memory; a finding that could improve our understanding of the evolutionary processes that produce and maintain intraspecific behavioural heterogeneity. Here, we tested whether boldness, the most studied personality trait in fish, could predict learning ability in brook trout. After quantifying boldness, fish were trained to find a hidden food patch in a maze environment. Stable landmark cues were provided to indicate the location of food and, at the conclusion of training, cues were rearranged to test for learning. There was a negative relationship between boldness and learning as shy fish were increasingly more successful at navigating the maze and locating food during training trials compared to bold fish. In the altered testing environment, only shy fish continued using cues to search for food. Overall, the learning rate of bold fish was found to be lower than that of shy fish for several metrics suggesting that personality could have widespread effects on behaviour. Because learning can increase plasticity to environmental change, these results have significant implications for fish conservation.

  9. The influence of insurance status on waiting times in German acute care hospitals: an empirical analysis of new data

    PubMed Central

    2009-01-01

    Background There is an ongoing debate in Germany about the assumption that patients with private health insurance (PHI) benefit from better access to medical care, including shorter waiting times (Lüngen et al. 2008), compared to patients with statutory health insurance (SHI). Problem Existing analyses of the determinants for waiting times in Germany are a) based on patient self-reports and b) do not cover the inpatient sector. This paper aims to fill both gaps by (i) generating new primary data and (ii) analyzing waiting times in German hospitals. Methods We requested individual appointments from 485 hospitals within an experimental study design, allowing us to analyze the impact of PHI versus SHI on waiting times (Asplin et al. 2005). Results In German acute care hospitals patients with PHI have significantly shorter waiting times than patients with SHI. Conclusion Discrimination in waiting times by insurance status does occur in the German acute hospital sector. Since there is very little transparency in treatment quality in Germany, we do not know whether discrimination in waiting times leads to discrimination in the quality of treatment. This is an important issue for future research. PMID:20025744

  10. Does the Factor Structure of Military Sexual Stressors in Men Correspond to Women's? A Confirmatory Factor Analysis Using the Sexual Harassment Inventory.

    PubMed

    Reddy, Madhavi K; Murdoch, Maureen

    2016-02-01

    Unwanted sexual stressors experienced by military men and women are associated with a host of negative physical and mental health problems. Government officials are making it a priority to put a stop to these unwanted sexual experiences. However, the measure typically used measures sexual stressors much better for women than for men. The purpose of the present study was to test the factor structure of an alternative measure, the Sexual Harassment Inventory (SHI), to examine whether sexual stressors experienced by men correspond to women's experiences. We used three preexisting datasets in which the SHI was used to assess active and former military members' sexual stressor experiences. We conducted an exploratory factor analysis to identify women's response patterns and a confirmatory factor analysis to determine whether men's response patterns corresponded to women's. Findings showed that the SHI has evidence of factorial validity in female service members and adequate, but not exceptional, factorial fit for male service members. It is imperative that more work be done to better understand how men experience and perceive potential military sexual stressors and how those perceptions and experiences compare to women's. Reprint & Copyright © 2016 Association of Military Surgeons of the U.S.

  11. Biased Facial Expression Interpretation in Shy Children

    ERIC Educational Resources Information Center

    Kokin, Jessica; Younger, Alastair; Gosselin, Pierre; Vaillancourt, Tracy

    2016-01-01

    The relationship between shyness and the interpretations of the facial expressions of others was examined in a sample of 123 children aged 12 to 14?years. Participants viewed faces displaying happiness, fear, anger, disgust, sadness, surprise, as well as a neutral expression, presented on a computer screen. The children identified each expression…

  12. KSC-02pd0757

    NASA Image and Video Library

    2002-05-24

    KENNEDY SPACE CENTER, FLA. -- Dressed in bunny suits, STS-107 Payload Commander Michael Anderson (left) and 107 Payload Specialist Ilan Ramon (right), who is with the Israeli Space Agency, review data in Columbia's payload bay for the Fast Reaction Experiments Enabling Science, Technology, Applications and Research (FREESTAR) experiments for the mission. FREESTAR comprises Mediterranean Israeli Dust, Solar Constant, Shuttle Ozone Limb Sounding, Critical Viscosity of Xenon, Low Power, and Space Experimental Module experiments. Another payload is the SHI Research Double Module (SHI/RDM), also known as SPACEHAB. The experiments range from material sciences to life sciences. STS-107 is scheduled to launch July 11, 2002

  13. KSC-02pd0753

    NASA Image and Video Library

    2002-05-24

    KENNEDY SPACE CENTER, FLA. - STS-107 Payload Specialist Ilan Ramon (left), with the Israeli Space Agency, and Payload Commander Michael Anderson pause during a payload check in the Orbiter Processing Facility. A research mission, STS-107 will carry as the primary payload the first flight of the SHI Research Double Module (SHI/RDM), also known as SPACEHAB. The experiments range from material sciences to life sciences. Another payload is FREESTAR (Fast Reaction Experiments Enabling Science, Technology, Applications and Research) comprising Mediterranean Israeli Dust, Solar Constant, Shuttle Ozone Limb Sounding, Critical Viscosity of Xenon, Low Power, and Space Experimental Module experiments. STS-107 is scheduled to launch July 11, 2002

  14. KSC-02pd0755

    NASA Image and Video Library

    2002-05-24

    KENNEDY SPACE CENTER, FLA. -- Dressed in bunny suits, STS-107 Payload Commander Michael Anderson (left) and 107 Payload Specialist Ilan Ramon, with the Israeli Space Agency, are ready to enter Columbia's payload bay to work on Fast Reaction Experiments Enabling Science, Technology, Applications and Research (FREESTAR) experiments for the mission. FREESTAR comprises Mediterranean Israeli Dust, Solar Constant, Shuttle Ozone Limb Sounding, Critical Viscosity of Xenon, Low Power, and Space Experimental Module experiments. Another payload is the SHI Research Double Module (SHI/RDM), also known as SPACEHAB. The experiments range from material sciences to life sciences. STS-107 is scheduled to launch July 11, 2002

  15. Natural History Study of Synucleinopathies

    ClinicalTrials.gov

    2018-01-23

    Patients With Synucleinopathies; Neurogenic Orthostatic Hypotension; Pure Autonomic Failure; REM Sleep Behavior Disorder; Parkinson Disease; Dementia With Lewy Bodies; Multiple System Atrophy; Shy-Drager Disease

  16. [Declared dead? Recommendations regarding integrated care from the perspective of German statutory health insurance].

    PubMed

    Amelung, Volker; Wolf, S; Ozegowski, S; Eble, S; Hildebrandt, H; Knieps, F; Lägel, R; Schlenker, R-U; Sjuts, R

    2015-04-01

    The traditional separation of health care into sectors in Germany causes communication problems that hinder continuous, patient-oriented care. This is most evident in the transition from inpatient to outpatient care. That said, there are also breaks in the flow of information, a lack of supply, or even incorrect information flowing within same-sector care. The transition from a division of functions into sectors to a patient-oriented process represents a change in the paradigm of health care that can only be successfully completed with considerable effort. Germany's statutory health insurance (SHI) funds play a key role here, as they are the contracting parties as well as the financiers of integrated care, and are strategically located at the center of the development process.The objective of this article is to explore how Germany's SHI funds view integrated care, what they regard as being the drivers of and barriers to transitioning to such a system, and what recommendations they can provide with regard to the further development of integrated care. For this purpose semi-structured interviews with board members and those responsible for implementing integrated care into the operations of ten SHI funds representing more than half of Germany's SHI-insured population were conducted. According to the interviewees, a better framework for integrated care urgently needs to be developed and rendered more receptive to innovation.Only in this way will the widespread stagnation of the past several years be overcome. The deregulation of § 140a-d SGB V and the establishment of a uniform basis for new forms of care in terms of a new innovation clause are among the central recommendations of this article. The German federal government's innovation fund was met with great hope, but also implied risks. Nonetheless, the new law designed to strengthen health care overall generated high expectations.

  17. The disparity in access to new medication by type of health insurance: lessons from Germany.

    PubMed

    Krobot, Karl J; Miller, William C; Kaufman, Jay S; Christensen, Dale B; Preisser, John S; Ibrahim, Michel A

    2004-05-01

    Drug provision within the German statutory health insurance system has undergone several reforms, including the introduction of drug macrobudgets in 1993. The objective of this study was to investigate the extent to which statutorily (SHI) and fully privately (PHI) health-insured patients were provided with new medication recommended by professional bodies in an equitable fashion using the example of migraine patients. We conducted a retrospective cohort study. A total of 367 primary-care practices (MediPlus, IMS Health) in Germany in the second year of the HealthCare Structural Reform Act were studied. Subjected consisted of 7703 SHI and 470 PHI migraineurs (International Classification of Diseases, 10th edition G43) aged 18 to 65 years at their first migraine prescription visit in 1994. We compared prescription of oral or subcutaneous serotonin 5HT1B/1D receptor agonist sumatriptan with nonserotoninergic migraine therapy. In multiplicative risk regression with variance estimation accounting for clustering of patients within practices, PHI patients were 2.3 times (95% confidence interval [CI], 1.6-3.3) more likely to receive sumatriptan than their SHI counterparts at the mean age of the cohorts (43 years) adjusted for incident versus prevalent migraine treatment, the gender of the patient, the age, gender, and primary care specialist group of the physician, and the type and the community size class of the practice. This disparity widened by 38% (95% CI, 1-88%) every 10 years of patient age. Even though virtually everyone in Germany has health insurance and drug coverage, use of new and recommended migraine medicines was less common among those with SHI compared with their privately insured counterparts. Systematic studies of access to health care recommended by professional bodies will be critically important to ensure delivery of high-quality health care for all patients.

  18. KSC-03pd0128

    NASA Image and Video Library

    2003-01-16

    KENNEDY SPACE CENTER, FLA. -- Against a backdrop of blue sky and the blue Atlantic Ocean, launch of Space Shuttle Columbia is reflected in the nearby water. Following a flawless and uneventful countdown, liftoff occurred on-time at 10:39 a.m. EST. The 16-day STS-107 research mission will include FREESTAR (Fast Reaction Experiments Enabling Science, Technology, Applications and Research) and the SHI Research Double Module (SHI/RDM), known as SPACEHAB. Experiments on the module range from material sciences to life sciences. This mission is the first Shuttle mission of 2003. Mission STS-107 is the 28th flight of the orbiter Columbia and the 113th flight overall in NASA's Space Shuttle program.

  19. Comment on "Comparative study of ab initio nonradiative recombination rate calculations under different formalisms"

    NASA Astrophysics Data System (ADS)

    Wickramaratne, Darshana; Shen, Jimmy-Xuan; Alkauskas, Audrius; Van de Walle, Chris G.

    2018-02-01

    In a recent article [Phys. Rev. B 91, 205315 (2015), 10.1103/PhysRevB.91.205315] Shi, Xu, and Wang presented a comparison of several formalisms to calculate nonradiative recombination rates and concluded the "one-dimensional (1D) quantum formula" that was used by Alkauskas et al. [Phys. Rev. B 90, 075202 (2014), 10.1103/PhysRevB.90.075202] is insufficient to accurately describe nonradiative capture rates. Our analysis of the results of Shi, Xu, and Wang indicates that their conclusions about the 1D quantum formula are unfounded and stem from an error in their calculations. Our own calculations demonstrate that the 1D quantum formula approach yields reliable and accurate results for nonradiative recombination rates.

  20. KSC-02pd0754

    NASA Image and Video Library

    2002-05-24

    KENNEDY SPACE CENTER, FLA. -- In the Orbiter Processing Facility, STS-107 Payload Commander Michael Anderson (left) and 107 Payload Specialist Ilan Ramon, with the Israeli Space Agency, look at one of the main engines on Columbia. A research mission, STS-107 will carry as the primary payload the first flight of the SHI Research Double Module (SHI/RDM), also known as SPACEHAB. The experiments range from material sciences to life sciences. Another payload is FREESTAR (Fast Reaction Experiments Enabling Science, Technology, Applications and Research) comprising Mediterranean Israeli Dust, Solar Constant, Shuttle Ozone Limb Sounding, Critical Viscosity of Xenon, Low Power, and Space Experimental Module experiments. STS-107 is scheduled to launch July 11, 2002

  1. Causes of chronic orthostatic hypotension

    NASA Technical Reports Server (NTRS)

    Robertson, D.; Robertson, R. M.

    1994-01-01

    OBJECTIVE: To determine the frequency of various causes of orthostatic hypotension. DESIGN: Survey. SETTING: Tertiary referral center. PATIENTS: One hundred patients with moderate to severe orthostatic hypotension. RESULTS: Twenty-seven percent of the patients had primary autonomic failure, 35% had secondary autonomic failure, and 38% had hypotension without evidence of generalized autonomic degeneration. CONCLUSIONS: In a tertiary referral center, only a minority of patients with severe orthostatic hypotension will have Shy-Drager syndrome or Bradbury-Eggleston syndrome as their primary disease. Occasional patients who initially appear to have Bradbury-Eggleston syndrome ultimately prove to have Shy-Drager syndrome or paraneoplastic autonomic failure. Antidepressant drugs, even in low doses, remain a major overlooked cause of orthostatic hypotension.

  2. Kinetics of propagation of the lattice excitation in a swift heavy ion track

    NASA Astrophysics Data System (ADS)

    Lipp, V. P.; Volkov, A. E.; Sorokin, M. V.; Rethfeld, B.

    2011-05-01

    In this research we verify the applicability of the temperature and heat diffusion conceptions for the description of subpicosecond lattice excitations in nanometric tracks of swift heavy ions (SHI) decelerated in solids in the electronic stopping regime. The method is based on the molecular dynamics (MD) analysis of temporal evolutions of the local kinetic and configurational temperatures of a lattice. We used solid argon as the model system. MD simulations demonstrated that in a SHI track (a) thermalization of lattice excitations takes time of several picoseconds, and (b) application of the parabolic heat diffusion equations for the description of spatial and temporal propagation of lattice excitations is questionable at least up to 10 ps after the ion passage.

  3. Ground Deformation near active faults in the Kinki district, southwest Japan, detected by InSAR

    NASA Astrophysics Data System (ADS)

    Hashimoto, M.; Ozawa, T.

    2016-12-01

    The Kinki district, southwest Japan, consists of ranges and plains between which active faults reside. The Osaka plain is in the middle of this district and is surrounded by the Rokko, Arima-Takatsuki, Ikoma, Kongo and Median Tectonic Line fault zones in the clockwise order. These faults are considered to be capable to generate earthquakes of larger magnitude than 7. The 1995 Kobe earthquake is the most recent activity of the Rokko fault (NE-SW trending dextral fault). Therefore the monitoring of ground deformation with high spatial resolution is essential to evaluate seismic hazards in this area. We collected and analyzed available SAR images such as ERS-1/2, Envisat, JERS-1, TerraSAR-X, ALOS/PALSAR and ALOS-2/PALSAR-2 to reveal ground deformation during these 20 years. We made DInSAR and PSInSAR analyses of these images using ASTER-GDEM ver.2. We detected three spots of subsidence along the Arima-Takatsuki fault (ENE-WSW trending dextral fault, east neighbor of the Rokko fault) after the Kobe earthquake, which continued up to 2010. Two of them started right after the Kobe earthquake, while the easternmost one was observed after 2000. However, we did not find them in the interferograms of ALOS-2/PALSAR-2 acquired during 2014 - 2016. Marginal uplift was recognized along the eastern part of the Rokko fault. PS-InSAR results of ALOS/PALSAR also revealed slight uplift north of the Rokko Mountain that uplift by 20 cm coseismically. These observations suggest that the Rokko Mountain might have uplifted during the postseismic period. We found subsidence on the eastern frank of the Kongo Mountain, where the Kongo fault (N-S trending reverse fault) exits. In the southern neighbor of the Median Tectonic Line (ENE-WSW trending dextral fault), uplift of > 5 mm/yr was found by Envisat and ALOS/PALSAR images. This area is shifted westward by 4 mm/yr as well. Since this area is located east of a seismically active area in the northwestern Wakayama prefecture, this deformation

  4. Can personality predict individual differences in brook trout spatial learning ability?

    PubMed

    White, S L; Wagner, T; Gowan, C; Braithwaite, V A

    2017-08-01

    While differences in individual personality are common in animal populations, understanding the ecological significance of variation has not yet been resolved. Evidence suggests that personality may influence learning and memory; a finding that could improve our understanding of the evolutionary processes that produce and maintain intraspecific behavioural heterogeneity. Here, we tested whether boldness, the most studied personality trait in fish, could predict learning ability in brook trout. After quantifying boldness, fish were trained to find a hidden food patch in a maze environment. Stable landmark cues were provided to indicate the location of food and, at the conclusion of training, cues were rearranged to test for learning. There was a negative relationship between boldness and learning as shy fish were increasingly more successful at navigating the maze and locating food during training trials compared to bold fish. In the altered testing environment, only shy fish continued using cues to search for food. Overall, the learning rate of bold fish was found to be lower than that of shy fish for several metrics suggesting that personality could have widespread effects on behaviour. Because learning can increase plasticity to environmental change, these results have significant implications for fish conservation. Copyright © 2016 Elsevier B.V. All rights reserved.

  5. Adapted intervention mapping: a strategic planning process for increasing physical activity and healthy eating opportunities in schools via environment and policy change.

    PubMed

    Belansky, Elaine S; Cutforth, Nick; Chavez, Robert; Crane, Lori A; Waters, Emily; Marshall, Julie A

    2013-03-01

    School environment and policy changes have increased healthy eating and physical activity; however, there has been modest success in translating research findings to practice. The School Environment Project tested whether an adapted version of Intervention Mapping (AIM) resulted in school change. Using a pair randomized design, 10 rural elementary schools were assigned to AIM or the School Health Index (SHI). Baseline measures were collected fall 2005, AIM was conducted 2005-2006, and follow-up measures were collected fall 2006 and 2007. Outcome measures included number and type of effective environment and policy changes implemented; process measures included the extent to which 11 implementation steps were used. AIM schools made an average of 4.4 effective changes per school with 90% still in place a year later. SHI schools made an average of 0.6 effective changes with 66% in place a year later. Implementation steps distinguishing AIM from SHI included use of external, trained facilitators; principal involvement; explicitly stating the student behavior goals; identifying effective environment and policy changes; prioritizing potential changes based on importance and feasibility; and developing an action plan. The AIM process led to environment and policy changes known to increase healthy eating and physical activity. © 2013, American School Health Association.

  6. Enhanced sensitivity to glucocorticoids in cytarabine-resistant AML.

    PubMed

    Malani, D; Murumägi, A; Yadav, B; Kontro, M; Eldfors, S; Kumar, A; Karjalainen, R; Majumder, M M; Ojamies, P; Pemovska, T; Wennerberg, K; Heckman, C; Porkka, K; Wolf, M; Aittokallio, T; Kallioniemi, O

    2017-05-01

    We sought to identify drugs that could counteract cytarabine resistance in acute myeloid leukemia (AML) by generating eight resistant variants from MOLM-13 and SHI-1 AML cell lines by long-term drug treatment. These cells were compared with 66 ex vivo chemorefractory samples from cytarabine-treated AML patients. The models and patient cells were subjected to genomic and transcriptomic profiling and high-throughput testing with 250 emerging and clinical oncology compounds. Genomic profiling uncovered deletion of the deoxycytidine kinase (DCK) gene in both MOLM-13- and SHI-1-derived cytarabine-resistant variants and in an AML patient sample. Cytarabine-resistant SHI-1 variants and a subset of chemorefractory AML patient samples showed increased sensitivity to glucocorticoids that are often used in treatment of lymphoid leukemia but not AML. Paired samples taken from AML patients before treatment and at relapse also showed acquisition of glucocorticoid sensitivity. Enhanced glucocorticoid sensitivity was only seen in AML patient samples that were negative for the FLT3 mutation (P=0.0006). Our study shows that development of cytarabine resistance is associated with increased sensitivity to glucocorticoids in a subset of AML, suggesting a new therapeutic strategy that should be explored in a clinical trial of chemorefractory AML patients carrying wild-type FLT3.

  7. Enhanced sensitivity to glucocorticoids in cytarabine-resistant AML

    PubMed Central

    Malani, D; Murumägi, A; Yadav, B; Kontro, M; Eldfors, S; Kumar, A; Karjalainen, R; Majumder, M M; Ojamies, P; Pemovska, T; Wennerberg, K; Heckman, C; Porkka, K; Wolf, M; Aittokallio, T; Kallioniemi, O

    2017-01-01

    We sought to identify drugs that could counteract cytarabine resistance in acute myeloid leukemia (AML) by generating eight resistant variants from MOLM-13 and SHI-1 AML cell lines by long-term drug treatment. These cells were compared with 66 ex vivo chemorefractory samples from cytarabine-treated AML patients. The models and patient cells were subjected to genomic and transcriptomic profiling and high-throughput testing with 250 emerging and clinical oncology compounds. Genomic profiling uncovered deletion of the deoxycytidine kinase (DCK) gene in both MOLM-13- and SHI-1-derived cytarabine-resistant variants and in an AML patient sample. Cytarabine-resistant SHI-1 variants and a subset of chemorefractory AML patient samples showed increased sensitivity to glucocorticoids that are often used in treatment of lymphoid leukemia but not AML. Paired samples taken from AML patients before treatment and at relapse also showed acquisition of glucocorticoid sensitivity. Enhanced glucocorticoid sensitivity was only seen in AML patient samples that were negative for the FLT3 mutation (P=0.0006). Our study shows that development of cytarabine resistance is associated with increased sensitivity to glucocorticoids in a subset of AML, suggesting a new therapeutic strategy that should be explored in a clinical trial of chemorefractory AML patients carrying wild-type FLT3. PMID:27833094

  8. The response of phospholipid-encapsulated microbubbles to chirp-coded excitation: Implications for high-frequency nonlinear imaging

    PubMed Central

    Shekhar, Himanshu; Doyley, Marvin M.

    2013-01-01

    The current excitation strategy for harmonic and subharmonic imaging (HI and SHI) uses short sine-bursts. However, alternate pulsing strategies may be useful for enhancing nonlinear emissions from ultrasound contrast agents. The goal of this study was to corroborate the hypothesis that chirp-coded excitation can improve the performance of high-frequency HI and SHI. A secondary goal was to understand the mechanisms that govern the response of ultrasound contrast agents to chirp-coded and sine-burst excitation schemes. Numerical simulations and acoustic measurements were conducted to evaluate the response of a commercial contrast agent (Targestar-P®) to chirp-coded and sine-burst excitation (10 MHz frequency, peak pressures 290 kPa). The results of the acoustic measurements revealed an improvement in signal-to-noise ratio by 4 to 14 dB, and a two- to threefold reduction in the subharmonic threshold with chirp-coded excitation. Simulations conducted with the Marmottant model suggest that an increase in expansion-dominated radial excursion of microbubbles was the mechanism responsible for the stronger nonlinear response. Additionally, chirp-coded excitation detected the nonlinear response for a wider range of agent concentrations than sine-bursts. Therefore, chirp-coded excitation could be a viable approach for enhancing the performance of HI and SHI. PMID:23654417

  9. The response of phospholipid-encapsulated microbubbles to chirp-coded excitation: implications for high-frequency nonlinear imaging.

    PubMed

    Shekhar, Himanshu; Doyley, Marvin M

    2013-05-01

    The current excitation strategy for harmonic and subharmonic imaging (HI and SHI) uses short sine-bursts. However, alternate pulsing strategies may be useful for enhancing nonlinear emissions from ultrasound contrast agents. The goal of this study was to corroborate the hypothesis that chirp-coded excitation can improve the performance of high-frequency HI and SHI. A secondary goal was to understand the mechanisms that govern the response of ultrasound contrast agents to chirp-coded and sine-burst excitation schemes. Numerical simulations and acoustic measurements were conducted to evaluate the response of a commercial contrast agent (Targestar-P(®)) to chirp-coded and sine-burst excitation (10 MHz frequency, peak pressures 290 kPa). The results of the acoustic measurements revealed an improvement in signal-to-noise ratio by 4 to 14 dB, and a two- to threefold reduction in the subharmonic threshold with chirp-coded excitation. Simulations conducted with the Marmottant model suggest that an increase in expansion-dominated radial excursion of microbubbles was the mechanism responsible for the stronger nonlinear response. Additionally, chirp-coded excitation detected the nonlinear response for a wider range of agent concentrations than sine-bursts. Therefore, chirp-coded excitation could be a viable approach for enhancing the performance of HI and SHI.

  10. Effect of rapid thermal annealing on nanocrystalline TiO2 thin films synthesized by swift heavy ion irradiation

    NASA Astrophysics Data System (ADS)

    Thakurdesai, Madhavi; Kanjilal, D.; Bhattacharyya, Varsha

    2012-08-01

    Irradiation by swift heavy ions (SHI) is unique tool to synthesize nanocrystalline thin films. We have reported transformation of 100 nm thick amorphous films into nanocrystalline film due to irradiation by 100 MeV Ag ion beam. Oblate shaped nanoparticles having anatase phase of TiO2 were formed on the surface of the irradiated films. In the present investigation, these films are annealed at 350 °C for 2 min in oxygen atmosphere by Rapid Thermal Annealing (RTA) method. During RTA processing, the temperature rises abruptly and this thermal instability is expected to alter surface morphology, structural and optical properties of nanocrystalline TiO2 thin films. Thus in the present work, effect of RTA on SHI induced nanocrystalline thin films of TiO2 is studied. The effect of RTA processing on the shape and size of TiO2 nanoparticles is studied by Atomic Force Microscopy (AFM) and Scanning Electron Microscopy (SEM). Glancing Angle X-ray Diffraction (GAXRD) studies are carried to investigate structural changes induced by RTA processing. Optical characterization is carried out by UV-vis spectroscopy and photoluminescence (PL) spectroscopy. The changes observed in structural and optical properties of nanocrystalline TiO2 thin films after RTA processing are attributed to the annihilation of SHI induced defects.

  11. Naming psychosis: the Hong Kong experience.

    PubMed

    Chiu, Cindy P-Y; Lam, May M-L; Chan, Sherry K-W; Chung, Dicky W-S; Hung, Se-Fong; Tang, Jennifer Y-M; Wong, Gloria H-Y; Hui, Christy L-M; Chen, Eric Y-H

    2010-11-01

    Schizophrenia translates in Chinese as 'Mind Split Disease' which is heavily stigmatizing. The narrow conceptualization for schizophrenia alone was insufficient, in the context of early detection and intervention for psychosis. The need for an effective Chinese translation for psychotic disorders was imminent upon the launch of the Early Assessment Service for Young People with Psychosis in Hong Kong, where public awareness strategies had to be built upon effective communication of the disorder. 'Si Jue Shi Tiao', the new term for psychosis, described 'thought and perceptual dysregulation'. This new terminology and concept was strategically introduced to the local community. The term 'Si Jue Shi Tiao' was taken up well locally and had demonstrated interactions within the Chinese and East Asian communities. The public has taken in the broader concept of psychosis, in contrary to the previous concept of schizophrenia per se. In Hong Kong, the restrictive view of perceiving psychotic disorders as schizophrenia was broadened upon the introduction of a more embracing, less stigmatizing term 'Si Jue Shi Tiao'. Effective establishment of this term to the local vocabulary allowed a basis for communication as well as public education work. Further evaluation is necessary to determine the effectiveness of the naming and to guide further public awareness strategies. © 2010 Blackwell Publishing Asia Pty Ltd.

  12. Effects of important parameters variations on computing eigenspace-based minimum variance weights for ultrasound tissue harmonic imaging

    NASA Astrophysics Data System (ADS)

    Haji Heidari, Mehdi; Mozaffarzadeh, Moein; Manwar, Rayyan; Nasiriavanaki, Mohammadreza

    2018-02-01

    In recent years, the minimum variance (MV) beamforming has been widely studied due to its high resolution and contrast in B-mode Ultrasound imaging (USI). However, the performance of the MV beamformer is degraded at the presence of noise, as a result of the inaccurate covariance matrix estimation which leads to a low quality image. Second harmonic imaging (SHI) provides many advantages over the conventional pulse-echo USI, such as enhanced axial and lateral resolutions. However, the low signal-to-noise ratio (SNR) is a major problem in SHI. In this paper, Eigenspace-based minimum variance (EIBMV) beamformer has been employed for second harmonic USI. The Tissue Harmonic Imaging (THI) is achieved by Pulse Inversion (PI) technique. Using the EIBMV weights, instead of the MV ones, would lead to reduced sidelobes and improved contrast, without compromising the high resolution of the MV beamformer (even at the presence of a strong noise). In addition, we have investigated the effects of variations of the important parameters in computing EIBMV weights, i.e., K, L, and δ, on the resolution and contrast obtained in SHI. The results are evaluated using numerical data (using point target and cyst phantoms), and the proper parameters of EIBMV are indicated for THI.

  13. In-orbit performance of a helium dewar for the soft X-ray spectrometer onboard ASTRO-H

    NASA Astrophysics Data System (ADS)

    Yoshida, Seiji; Miyaoka, Mikio; Kanao, Ken'ichi; Tsunematsu, Shoji; Otsuka, Kiyomi; Hoshika, Shunji; Narasaki, Katsuhiro; Mitsuda, Kazuhisa; Yamasaki, Noriko; Takei, Yoh; Fujimoto, Ryuichi; Ezoe, Yuichiro; Sato, Yoichi; Okamoto, Atsushi; Noda, Hirofumi; DiPirro, Michael; Shirron, Peter

    2018-04-01

    ASTRO-H was an X-ray astronomy satellite that the Japan Aerospace Exploration Agency (JAXA) developed to study the evolution of the universe and physical phenomena yet to be discovered. The primary scientific instrument of ASTRO-H was the Soft X-ray Spectrometer (SXS). Its detectors were to be cooled to 50 m K using a complex cryogenic system with a multistage adiabatic demagnetization refrigerator (ADR) developed by the National Aeronautics and Space Administration (NASA), and a cryogenic system developed by Sumitomo Heavy Industries, Ltd. (SHI). SHI's cryogenic system was required to cool the ADR's heatsink to 1.3 K or less in orbit for three years or longer. To meet these requirements, SHI developed a hybrid cryogenic system consisting of a liquid helium tank, a 4 K Joule-Thomson cooler, and two two-stage Stirling coolers. ASTRO-H was launched from Tanegashima Space Center on February 17, 2016. The initial operation of the SXS cryogenic system in orbit was completed successfully. The cooling performance was as expected and could have exceeded the lifetime requirement of three years. This paper describes results of ground tests, results of top-off filling of superfluid liquid helium just before launch, and cooling performance in orbit.

  14. [Textual research on the time of completion of XU Shuwei' books on exo-pathogenic cold diseases].

    PubMed

    Lu, Mingxin

    2015-11-01

    Shang han bai zheng ge (Poets of Syndromes of Exo-pathogenic Cold Disease), Shang han fa wei lun (Discourse on Elucidation of Exo-pathogenic Cold Disease), Shang han jiu shi lun (90 Discourses on Exo-pathogenic Cold Disease) were the three extant books on exo-pathogenic cold disease written by Xu Shuwei among his other works of its kind. Although there were carved editions of the Yuan and Ming Dynasties, these books were gradually paid attention for citations by other physicians till the Qing Dynasty. Through comparison of its texts, it can be found that the title of Shang han bai zheng ge was mentioned in his other medical works. While Shang han fa wei lun and Shang han jiu shi lun contained some overlapping contents, some even carrying concept contradictory to each other. According to historical materials, Xu Shuwei began to write the above-mentioned 3 books in the Northern Song Dynasty. In the several early years of the Southern Song Dynasty after crossing the Yangtze River, he collected the remained manuscripts and continued to write. Among them, Shang han bai zheng ge was completed first, followed by Shang han fa wei lun, with Shang han jiu shi lun came as the last.

  15. Structural Diversities in Heterometallic Mn-Ca Cluster Chemistry from the Use of Salicylhydroxamic Acid: {MnIII4Ca2}, {MnII/III6Ca2}, {MnIII/IV8Ca}, and {MnIII8Ca2} Complexes with Relevance to Both High- and Low-Valent States of the Oxygen-Evolving Complex.

    PubMed

    Alaimo, Alysha A; Koumousi, Evangelia S; Cunha-Silva, Luís; McCormick, Laura J; Teat, Simon J; Psycharis, Vassilis; Raptopoulou, Catherine P; Mukherjee, Shreya; Li, Chaoran; Gupta, Sayak Das; Escuer, Albert; Christou, George; Stamatatos, Theocharis C

    2017-09-05

    One-pot reactions between the [Mn 3 O(O 2 CPh) 6 (py) x ] +/0 triangular precursors and either CaBr 2 ·xH 2 O or CaCl 2 ·6H 2 O, in the presence of salicylhydroxamic acid (shaH 2 ), have afforded the heterometallic complexes [Mn III 4 Ca 2 (O 2 CPh) 4 (shi) 4 (H 2 O) 3 (Me 2 CO)] (1) and (pyH)[Mn II 2 Mn III 4 Ca 2 Cl 2 (O 2 CPh) 7 (shi) 4 (py) 4 ] (2), respectively, in good yields. Further reactions but using a more flexible synthetic scheme comprising the Mn(NO 3 ) 2 ·4H 2 O/Ca(NO 3 ) 2 ·4H 2 O and Mn(O 2 CPh) 2 ·2H 2 O/Ca(ClO 4 ) 2 ·4H 2 O "metal blends" and shaH 2 , in the presence of external base NEt 3 , led to the new complexes (NHEt 3 ) 2 [Mn III 4 Mn IV 4 Ca(OEt) 2 (shi) 10 (EtOH) 2 ] (3) and (NHEt 3 ) 4 [Mn III 8 Ca 2 (CO 3 ) 4 (shi) 8 ] (4), respectively. In all reported compounds, the anion of the tetradentate (N,O,O,O)-chelating/bridging ligand salicylhydroxime (shi 3- ), resulting from the in situ metal-ion-assisted amide-iminol tautomerism of shaH 2 , was found to bridge both Mn and Ca atoms. Complexes 1-4 exhibit a variety of different structures, metal stoichiometries, and Mn oxidation-state descriptions; 1 possesses an overall octahedral metal arrangement, 2 can be described as a Mn 4 Ca 2 octahedron bound to an additional Mn 2 unit, 3 consists of a Mn 8 "ring" surrounding a Ca II atom, and 4 adopts a rectangular cuboidal motif of eight Mn atoms accommodating two Ca II atoms. Solid-state direct-current magnetic susceptibility studies revealed the presence of predominant antiferromagnetic exchange interactions between the Mn centers, leading to S = 0 spin ground-state values for all complexes. From a bioinorganic chemistry perspective, the reported compounds may demonstrate some relevance to both high-valent scheme (3) and lower-oxidation-level species (1, 2, and 4) of the catalytic cycle of the oxygen-evolving complex.

  16. Multiple mononeuropathy

    MedlinePlus

    Mononeuritis multiplex; Mononeuropathy multiplex; Multifocal neuropathy; Peripheral neuropathy - mononeuritis multiplex ... Philadelphia, PA: Elsevier; 2016:chap 107. Shy ME. Peripheral neuropathies. In: Goldman L, Schafer AI, eds. Goldman's Cecil ...

  17. Peripheral neuropathy

    MedlinePlus

    ... peripheral; Neuritis - peripheral; Nerve disease; Polyneuropathy; Chronic pain - peripheral neuropathy ... Philadelphia, PA: Elsevier; 2016:chap 107. Shy ME. Peripheral neuropathies. In: Goldman L, Schafer AI, eds. Goldman's Cecil ...

  18. Waste-to-energy incineration plants as greenhouse gas reducers: a case study of seven Japanese metropolises.

    PubMed

    Tabata, Tomohiro

    2013-11-01

    Municipal solid waste (MSW) incineration is a greenhouse gas (GHG) emitter; however, if GHG reductions, achieved by accounting for waste-to-energy, exceed GHG emissions, incineration can be considered as a net GHG reducer. In Japan, only 24.5% of MSW incineration plants perform energy recovery despite 80% of MSW being incinerated; therefore, there is great potential to extract more energy from MSW. In this study, the factors that should be considered to achieve net GHG reductions from incineration were analysed from a life cycle perspective. These considerations were then applied to the energy supply requirements in seven Japanese metropolises. Firstly, the carbon footprints of approximately 1500 incineration plants in Japan were calculated. Then, the incineration plants with negative carbon footprint values were classified as net GHG reducers. Next, the processes that contribute to the carbon footprint were evaluated, and two processes-plastic burning and electricity savings-were found to have the greatest influence. Based on the results, the energy supply requirements were analysed and discussed for seven metropolises (Sapporo, Tokyo, Nagoya, Osaka, Kobe, Takamatsu and Fukuoka) taking into account the energy demands of households. In Kobe, 16.2% of the electricity demand and 25.0% of the hot water demand could be satisfied by incineration to realise a net GHG reducer, although urban design for energy utilisation would be required.

  19. Integrated study of high resolution geophysical and geological information of Osaka Bay, Southwest Japan

    NASA Astrophysics Data System (ADS)

    Inoue, Naoto; Kitada, Naoko; Itoh, Yasuto; Takemura, Keiji; Nakagawa, Koichi

    The stratigraphic framework of Quaternary sediments in the Osaka Basin, Southwest Japan was revealed by high resolution geophysical and geological surveys acquired after the 1995 Kobe Earthquake. Osaka Bay is located in the central part of the Osaka Basin and is underlaid with Pre-Neogene basement rocks covered by an unconsolidated sequence of Plio-Pleistocene marine, fluvial and lacustrine sediments. Fifteen laterally continuous marine clays (from Ma-1 to Ma13, in ascending order) have been identified throughout the Osaka Basin that have been correlated with the marine eustatic record. Deep borehole and high resolution seismic data were acquired in Kobe (northern part of the basin) and Kansai International Airport (southern part of the basin). Sequence stratigraphy defined by seismic reflectors was used to reveal the stratigraphic differences between the two areas. By identifying reflectors as marine clay layers throughout the basin, we were able to divide the study area into three parts (northern, middle and southern parts) and to estimate the sedimentation rate in each location. The sedimentation rate increases from the northern and southern margins of the basin towards central Osaka Bay in the middle of the basin. In the southern parts, the sharp decline of sedimentation rate between Ma2 and Ma4 and thinning or complete lack of the reflectors corresponding to Ma5 and Ma6 layers result from tilting in this region.

  20. Sleep Problem of Children with Autistic Spectrum Disorder Assessed by Children Sleep Habits Questionnaire-Abbreviated in Indonesia and Japan.

    PubMed

    Irwanto; Rehatta, Nancy Margarita; Hartini, Sri; Takada, Satoshi

    2016-07-04

    Sleep problems are associated with problems of cognitive functioning, learning, attention and school performance. It has been found that sleep problems are highly prevalent in children with Autistic spectrum disorders (ASD), with rates ranging from 40% to 80%. We aimed to identify the prevalence of sleep problems on children with ASD in Indonesia and Japan. A cross-sectional study was conducted in Surabaya, Indonesia and Kobe, Japan. Children aged 4 -10 years old were enrolled using stratified cluster sampling. Children's Sleep Habits Questionnaire-Abbreviated (CSHQ-A) was used in this research to assess the sleep problems, consisted of 22 questions (NICHD SECCYD-Wisconsin). Data were analyzed with Mann-Whitney U test to compare the CSHQ-A scores between Indonesian and Japanese children, while the proportion of sleep problems was evaluated by chi-square test with 95% confidence interval. Fifty children with ASD were included in this study, 25 children from Kobe, Japan and 25 children from Surabaya, Indonesia. The prevalence of sleep problems on children with ASD was 60% (15 children) in Indonesia and 16% (4 children) in Japan respectively. There were significant differences in total waking during the night and in morning wake for the CSHQ-A between children from Indonesia and Japan (p<0.005). The prevalence of sleep problems on children with ASD was higher in children from Indonesia than from Japan.

  1. Optical methods in fault dynamics

    NASA Astrophysics Data System (ADS)

    Uenishi, K.; Rossmanith, H. P.

    2003-10-01

    The Rayleigh pulse interaction with a pre-stressed, partially contacting interface between similar and dissimilar materials is investigated experimentally as well as numerically. This study is intended to obtain an improved understanding of the interface (fault) dynamics during the earthquake rupture process. Using dynamic photoelasticity in conjunction with high-speed cinematography, snapshots of time-dependent isochromatic fringe patterns associated with Rayleigh pulse-interface interaction are experimentally recorded. It is shown that interface slip (instability) can be triggered dynamically by a pulse which propagates along the interface at the Rayleigh wave speed. For the numerical investigation, the finite difference wave simulator SWIFD is used for solving the problem under different combinations of contacting materials. The effect of acoustic impedance ratio of the two contacting materials on the wave patterns is discussed. The results indicate that upon interface rupture, Mach (head) waves, which carry a relatively large amount of energy in a concentrated form, can be generated and propagated from the interface contact region (asperity) into the acoustically softer material. Such Mach waves can cause severe damage onto a particular region inside an adjacent acoustically softer area. This type of damage concentration might be a possible reason for the generation of the "damage belt" in Kobe, Japan, on the occasion of the 1995 Hyogo-ken Nanbu (Kobe) Earthquake.

  2. KSC-03pd0117

    NASA Image and Video Library

    2003-01-16

    KENNEDY SPACE CENTER, FLA. - A crowd by the countdown clock watches as Space Shuttle Columbia roars toward space on mission STS-107. Following a flawless and uneventful countdown, liftoff occurred on-time at 10:39 a.m. EST. The 16-day research mission will include FREESTAR (Fast Reaction Experiments Enabling Science, Technology, Applications and Research) and the SHI Research Double Module (SHI/RDM), known as SPACEHAB. Experiments on the module range from material sciences to life sciences. Landing is scheduled at about 8:53 a.m. EST on Saturday, Feb. 1. This mission is the first Shuttle mission of 2003. Mission STS-107 is the 28th flight of the orbiter Columbia and the 113th flight overall in NASA's Space Shuttle program.

  3. KSC-03pd0116

    NASA Image and Video Library

    2003-01-16

    KENNEDY SPACE CENTER, FLA. - Seconds after launch, Space Shuttle Columbia appears as a flaming tip of the smoke column it trails. Following a flawless and uneventful countdown, liftoff occurred on-time at 10:39 a.m. EST. The 16-day research mission will include FREESTAR (Fast Reaction Experiments Enabling Science, Technology, Applications and Research) and the SHI Research Double Module (SHI/RDM), known as SPACEHAB. Experiments on the module range from material sciences to life sciences. Landing is scheduled at about 8:53 a.m. EST on Saturday, Feb. 1. This mission is the first Shuttle mission of 2003. Mission STS-107 is the 28th flight of the orbiter Columbia and the 113th flight overall in NASA's Space Shuttle program.

  4. KSC-03pp0142

    NASA Image and Video Library

    2003-01-16

    KENNEDY SPACE CENTER, FLA. - A closeup camera view shows Space Shuttle Columbia as it lifts off from Launch Pad 39A on mission STS-107. Following a flawless and uneventful countdown, liftoff occurred on-time at 10:39 a.m. EST. The 16-day research mission includes FREESTAR (Fast Reaction Experiments Enabling Science, Technology, Applications and Research) and the SHI Research Double Module (SHI/RDM), known as SPACEHAB. Experiments on the module range from material sciences to life sciences.. Landing of Columbia is scheduled at about 8:53 a.m. EST on Saturday, Feb. 1. This mission is the first Shuttle mission of 2003. Mission STS-107 is the 28th flight of the orbiter Columbia and the 113th flight overall in NASA's Space Shuttle program.

  5. KSC-03pd0119

    NASA Image and Video Library

    2003-01-16

    KENNEDY SPACE CENTER, FLA. -- Seconds after launch, Space Shuttle Columbia appears as a flaming tip of the smoke column it trails. Following a flawless and uneventful countdown, liftoff occurred on-time at 10:39 a.m. EST. The 16-day research mission will include FREESTAR (Fast Reaction Experiments Enabling Science, Technology, Applications and Research) and the SHI Research Double Module (SHI/RDM), known as SPACEHAB. Experiments on the module range from material sciences to life sciences. Landing is scheduled at about 8:53 a.m. EST on Saturday, Feb. 1. This mission is the first Shuttle mission of 2003. Mission STS-107 is the 28th flight of the orbiter Columbia and the 113th flight overall in NASA's Space Shuttle program.

  6. KSC-03pd0115

    NASA Image and Video Library

    2003-01-16

    KENNEDY SPACE CENTER, FLA. -- Trailing a twisting column of smoke, Space Shuttle Columbia hurtles toward space on mission STS-107. Following a flawless and uneventful countdown, liftoff occurred on-time at 10:39 a.m. EST. The 16-day research mission will include FREESTAR (Fast Reaction Experiments Enabling Science, Technology, Applications and Research) and the SHI Research Double Module (SHI/RDM), known as SPACEHAB. Experiments on the module range from material sciences to life sciences. Landing is scheduled at about 8:53 a.m. EST on Saturday, Feb. 1. This mission is the first Shuttle mission of 2003. Mission STS-107 is the 28th flight of the orbiter Columbia and the 113th flight overall in NASA's Space Shuttle program.

  7. KSC-03pd0111

    NASA Image and Video Library

    2003-01-16

    KENNEDY SPACE CENTER, FLA. -- Photographers and spectators watch from across the turn basin as Space Shuttle Columbia begins a perfect launch from Pad 39A following a flawless and uneventful countdown. Liftoff occurred on-time at 10:39 a.m. EST. The 16-day research mission will include FREESTAR (Fast Reaction Experiments Enabling Science, Technology, Applications and Research) and the SHI Research Double Module (SHI/RDM), known as SPACEHAB. Experiments on the module range from material sciences to life sciences. Landing is scheduled at about 8:53 a.m. EST on Saturday, Feb. 1. This mission is the first Shuttle mission of 2003. Mission STS-107 is the 28th flight of the orbiter Columbia and the 113th flight overall in NASA's Space Shuttle program.

  8. KSC-03pd0130

    NASA Image and Video Library

    2003-01-16

    KENNEDY SPACE CENTER, FLA. -- Space Shuttle Columbia seems to leap from amid the trees as it roars toward space on mission STS-107. Following a flawless and uneventful countdown, liftoff occurred on-time at 10:39 a.m. EST. The 16-day research mission will include FREESTAR (Fast Reaction Experiments Enabling Science, Technology, Applications and Research) and the SHI Research Double Module (SHI/RDM), known as SPACEHAB. Experiments on the module range from material sciences to life sciences.. Landing of Columbia is scheduled at about 8:53 a.m. EST on Saturday, Feb. 1. This mission is the first Shuttle mission of 2003. Mission STS-107 is the 28th flight of the orbiter Columbia and the 113th flight overall in NASA's Space Shuttle program.

  9. KSC-03pd0114

    NASA Image and Video Library

    2003-01-16

    KENNEDY SPACE CENTER, FLA. -- Space Shuttle Columbia hurtles through a perfect blue Florida sky following a flawless and uneventful countdown. Liftoff of Columbia on mission STS-107 occurred on-time at 10:39 a.m. EST. The 16-day research mission will include FREESTAR (Fast Reaction Experiments Enabling Science, Technology, Applications and Research) and the SHI Research Double Module (SHI/RDM), known as SPACEHAB. Experiments on the module range from material sciences to life sciences. Landing is scheduled at about 8:53 a.m. EST on Saturday, Feb. 1. This mission is the first Shuttle mission of 2003. Mission STS-107 is the 28th flight of the orbiter Columbia and the 113th flight overall in NASA's Space Shuttle program

  10. KSC-03pd0113

    NASA Image and Video Library

    2003-01-16

    KENNEDY SPACE CENTER, FLA. - Through a cloud-washed blue sky above Launch Pad 39A, Space Shuttle Columbia hurtles toward space on mission STS-107. Following a flawless and uneventful countdown, liftoff occurred on-time at 10:39 a.m. EST. The 16-day research mission will include FREESTAR (Fast Reaction Experiments Enabling Science, Technology, Applications and Research) and the SHI Research Double Module (SHI/RDM), known as SPACEHAB. Experiments on the module range from material sciences to life sciences. Landing is scheduled at about 8:53 a.m. EST on Saturday, Feb. 1. This mission is the first Shuttle mission of 2003. Mission STS-107 is the 28th flight of the orbiter Columbia and the 113th flight overall in NASA's Space Shuttle program.

  11. KSC-03PP-0146

    NASA Technical Reports Server (NTRS)

    2003-01-01

    KENNEDY SPACE CENTER, FLA. - STS-107 David Brown chats with the Closeout Crew during final preparations of his launch and entry suit in the White Room. The environmentally controlled chamber is mated to Space Shuttle Columbia for entry into the Shuttle. The hatch is seen in the background right. STS-107 is a mission devoted to research and will include more than 80 experiments that will study Earth and space science, advanced technology development, and astronaut health and safety. The payload on Space Shuttle Columbia includes FREESTAR (Fast Reaction Experiments Enabling Science, Technology, Applications and Research) and the SHI Research Double Module (SHI/RDM), known as SPACEHAB. Experiments on the module range from material sciences to life sciences. Liftoff is scheduled for 10:39 a.m. EST.

  12. Retracted: Long-term copper toxicity in apple trees (Malus pumila Mill) and bioaccumulation in fruits.

    PubMed

    Sun, Bai-Ye; Kan, Shi-Hong; Zhang, Yan-Zong; Wu, Jun; Deng, Shi-Huai; Liu, Chun-Sheng; Yang, Gang

    2010-01-15

    The following article from Environmental Toxicology, 'Long-term Copper Toxicity in Apple Trees (Malus pumila Mill) and Bioaccumulation in Fruits' by Bai-Ye Sun, Shi- Hong Kan, Yan-Zong Zhang, Jun Wu, Shi-Huai Deng, Chun-Sheng Liu and Gang Yang, published online on January 15, 2010 in Wiley InterScience (www.interscience.wiley.com; DOI: 10.1002/tox.20565), has been retracted by agreement between the authors, the journal Editor in Chief, Dr. Paul Tchounwou, and Wiley Periodicals, Inc. The retraction has been agreed at the request of the authors due to overlap with 'Copper Toxicity and Bioaccumulation in Chinese Cabbage (Brassica pekinensis Rupr.)' by Zhi-Ting Xiong and Hai Wang, published in Environmental Toxicology, Volume 20, pages 188-194, 2005.

  13. KSC-03pp0143

    NASA Image and Video Library

    2003-01-16

    KENNEDY SPACE CENTER, FLA. --Framed by branches across from Launch Pad 39A, Space Shuttle Columbia leaps toward space on mission STS-107. Following a flawless and uneventful countdown, liftoff occurred on-time at 10:39 a.m. EST. The 16-day research mission includes FREESTAR (Fast Reaction Experiments Enabling Science, Technology, Applications and Research) and the SHI Research Double Module (SHI/RDM), known as SPACEHAB. Experiments on the module range from material sciences to life sciences.. Landing of Columbia is scheduled at about 8:53 a.m. EST on Saturday, Feb. 1. This mission is the first Shuttle mission of 2003. Mission STS-107 is the 28th flight of the orbiter Columbia and the 113th flight overall in NASA's Space Shuttle program.

  14. KSC-03pp0141

    NASA Image and Video Library

    2003-01-16

    KENNEDY SPACE CENTER, FLA. - Viewed from among branches across from Launch Pad 39A, Space Shuttle Columbia leaps toward space on mission STS-107. Following a flawless and uneventful countdown, liftoff occurred on-time at 10:39 a.m. EST. The 16-day research mission includes FREESTAR (Fast Reaction Experiments Enabling Science, Technology, Applications and Research) and the SHI Research Double Module (SHI/RDM), known as SPACEHAB. Experiments on the module range from material sciences to life sciences.. Landing of Columbia is scheduled at about 8:53 a.m. EST on Saturday, Feb. 1. This mission is the first Shuttle mission of 2003. Mission STS-107 is the 28th flight of the orbiter Columbia and the 113th flight overall in NASA's Space Shuttle program.

  15. KSC-03pp0146

    NASA Image and Video Library

    2003-01-16

    KENNEDY SPACE CENTER, FLA. - STS-107 David Brown chats with the Closeout Crew during final preparations of his launch and entry suit in the White Room. The environmentally controlled chamber is mated to Space Shuttle Columbia for entry into the Shuttle. The hatch is seen in the background right. STS-107 is a mission devoted to research and will include more than 80 experiments that will study Earth and space science, advanced technology development, and astronaut health and safety. The payload on Space Shuttle Columbia includes FREESTAR (Fast Reaction Experiments Enabling Science, Technology, Applications and Research) and the SHI Research Double Module (SHI/RDM), known as SPACEHAB. Experiments on the module range from material sciences to life sciences. Liftoff is scheduled for 10:39 a.m. EST.

  16. KSC-03pp0144

    NASA Image and Video Library

    2003-01-16

    KENNEDY SPACE CENTER, FLA. -- STS-107 Mission Specialist Kalpana Chawla gets help with her launch and entry suit from the Closeout Crew in the White Room. The environmentally controlled chamber is mated to Space Shuttle Columbia for entry into the Shuttle. The hatch is seen in the background right. STS-107 is a mission devoted to research and will include more than 80 experiments that will study Earth and space science, advanced technology development, and astronaut health and safety. The payload on Space Shuttle Columbia includes FREESTAR (Fast Reaction Experiments Enabling Science, Technology, Applications and Research) and the SHI Research Double Module (SHI/RDM), known as SPACEHAB. Experiments on the module range from material sciences to life sciences. Liftoff is scheduled for 10:39 a.m. EST.

  17. KSC-03pp0147

    NASA Image and Video Library

    2003-01-16

    KENNEDY SPACE CENTER, FLA. -- STS-107 Payload Commander Michael Anderson gets help with his launch and entry suit from the Closeout Crew in the White Room. The environmentally controlled chamber is mated to Space Shuttle Columbia for entry into the Shuttle. Behind him is Pilot William "Willie" McCool. STS-107 is a mission devoted to research and will include more than 80 experiments that will study Earth and space science, advanced technology development, and astronaut health and safety. The payload on Space Shuttle Columbia includes FREESTAR (Fast Reaction Experiments Enabling Science, Technology, Applications and Research) and the SHI Research Double Module (SHI/RDM), known as SPACEHAB. Experiments on the module range from material sciences to life sciences. Liftoff is scheduled for 10:39 a.m. EST.

  18. Victorian Dragons: The Reluctant Brood.

    ERIC Educational Resources Information Center

    Berman, Ruth

    1984-01-01

    Relates why nineteenth century fantasy writers shied away from the use of dragons in their stories and rejoices over the return and happy transformation of this mythical beast in children's literature. (HOD)

  19. Iranian Influence in Iraqi Shi’a Groups

    DTIC Science & Technology

    2012-06-01

    Movement in Iraq, 254. 60 Jabar, The Shīʻite Movement in Iraq, 254. 61 Robert Fisk, The Great War For Civilisation : the Conquest of the Middle East...by Iran in 62 Fisk, The Great War For Civilisation : the Conquest of the Middle East, 647. 63 John...U.S. soldier missing in Iraq. AAH sources indicated that the group was not behind the killing but rather just mediators in the process of returning

  20. Childhood impulsive behavior and problem gambling by adulthood: A 30-year prospective community-based study

    PubMed Central

    Shenassa, Edmond D.; Paradis, Angela D.; Dolan, Sara L.; Wilhelm, Charlotte S.; Buka, Stephen L.

    2015-01-01

    Aims Problem gambling can create major financial, emotional and sometimes criminal problems for an individual. This study prospectively investigated the association between impulsive behavior at age 7 and the development of lifetime problem gambling by adulthood. We also examined the specificity of any observed association between impulsive behaviors and problem gambling by conducting parallel analyses examining the link between respondents’ shy/depressed behavior in childhood and later problem gambling. Design, setting and participants Cohort study of 958 offspring of mothers enrolled in the Collaborative Perinatal Project who participated in an adult follow-up study at a mean age of 39 years. Measurements Multivariable logistic regression models were fit to determine associations between psychologist-rated impulsive and shy/depressed behaviors at age 7 and lifetime self-reported gambling as measured by the South Oaks Gambling Screen administered during the adult follow-up study. Findings Children who exhibited impulsive behaviors at age 7, compared to their non-impulsive counterparts, were 3.09 (95% confidence interval: 1.40–6.82) times as likely to report problem gambling years later. In contrast, we did not find a significant association between childhood shy/depressed behavior and problem gambling by adulthood in adjusted analyses. Conclusions Impulsive behaviors at age 7 are a specific and significant risk factor for later problem gambling.. PMID:21752146

  1. Manufacturability of compact synchrotron mirrors

    NASA Astrophysics Data System (ADS)

    Douglas, Gary M.

    1997-11-01

    While many of the government funded research communities over the years have put their faith and money into increasingly larger synchrotrons, such as Spring8 in Japan, and the APS in the United States, a viable market appears to exist for smaller scale, research and commercial grade, compact synchrotrons. These smaller, and less expensive machines, provide the research and industrial communities with synchrotron radiation beamline access at a portion of the cost of their larger and more powerful counterparts. A compact synchrotron, such as the Aurora-2D, designed and built by Sumitomo Heavy Industries, Ltd. of japan (SHI), is a small footprint synchrotron capable of sustaining 20 beamlines. Coupled with a Microtron injector, with 150 MeV of injection energy, an entire facility fits within a 27 meter [88.5 ft] square floorplan. The system, controlled by 2 personal computers, is capable of producing 700 MeV electron energy and 300 mA stored current. Recently, an Aurora-2D synchrotron was purchased from SHI by the University of Hiroshima. The Rocketdyne Albuquerque Operations Beamline Optics Group was approached by SHI with a request to supply a group of 16 beamline mirrors for this machine. These mirrors were sufficient to supply 3 beamlines for the Hiroshima machine. This paper will address engineering issues which arose during the design and manufacturing of these mirrors.

  2. Zonula Occludens-1, Occludin and E-cadherin Expression and Organization in Salivary Glands with Sjögren’s Syndrome

    PubMed Central

    Mellas, Rachel E.; Leigh, Noel J.; Nelson, Joel W.; McCall, Andrew D.

    2015-01-01

    Sjögren’s syndrome (SS) is a chronic inflammatory autoimmune disorder that causes secretory dysfunction of the salivary glands leading to dry mouth. Previous studies reported that tight junction (TJ) proteins are down-regulated and lose polarity in human minor salivary glands with SS, suggesting that TJ structure is compromised in SS patients. In this paper, we utilized the NOD/ShiLtJ mouse with the main goal of evaluating this model for future TJ research. We found that the organization of apical proteins in areas proximal and distal to lymphocytic infiltration remained intact in mouse and human salivary glands with SS. These areas looked comparable to control glands (i.e., with no lymphocytic infiltration). TJ staining was absent in areas of lymphocytic infiltration coinciding with the loss of salivary epithelium. Gene expression studies show that most TJs are not significantly altered in 20-week-old NOD/ShiLtJ mice as compared with age-matched C57BL/6 controls. Protein expression studies revealed that the TJ proteins, zonula occludens-1 (ZO-1), occludin, claudin-12, as well as E-cadherin, do not significantly change in NOD/ShiLtJ mice. Our results suggest that ZO-1, occludin and E-cadherin are not altered in areas without lymphocytic infiltration. However, future studies will be necessary to test the functional aspect of these results. PMID:25248927

  3. Zonula occludens-1, occludin and E-cadherin expression and organization in salivary glands with Sjögren's syndrome.

    PubMed

    Mellas, Rachel E; Leigh, Noel J; Nelson, Joel W; McCall, Andrew D; Baker, Olga J

    2015-01-01

    Sjögren's syndrome (SS) is a chronic inflammatory autoimmune disorder that causes secretory dysfunction of the salivary glands leading to dry mouth. Previous studies reported that tight junction (TJ) proteins are down-regulated and lose polarity in human minor salivary glands with SS, suggesting that TJ structure is compromised in SS patients. In this paper, we utilized the NOD/ShiLtJ mouse with the main goal of evaluating this model for future TJ research. We found that the organization of apical proteins in areas proximal and distal to lymphocytic infiltration remained intact in mouse and human salivary glands with SS. These areas looked comparable to control glands (i.e., with no lymphocytic infiltration). TJ staining was absent in areas of lymphocytic infiltration coinciding with the loss of salivary epithelium. Gene expression studies show that most TJs are not significantly altered in 20-week-old NOD/ShiLtJ mice as compared with age-matched C57BL/6 controls. Protein expression studies revealed that the TJ proteins, zonula occludens-1 (ZO-1), occludin, claudin-12, as well as E-cadherin, do not significantly change in NOD/ShiLtJ mice. Our results suggest that ZO-1, occludin and E-cadherin are not altered in areas without lymphocytic infiltration. However, future studies will be necessary to test the functional aspect of these results. © The Author(s) 2014.

  4. Multiple system atrophy

    MedlinePlus

    ... syndrome; Neurologic orthostatic hypotension; Shy-McGee-Drager syndrome; Parkinson plus syndrome; MSA-P; MSA-C ... ncbi.nlm.nih.gov/pubmed/25587949 . Jankovic J. Parkinson disease and other movement disorders. In: Daroff RB, ...

  5. Topology and Foundations of Quantum Algorithms

    DTIC Science & Technology

    2005-07-01

    Several visitors to UCSD and IU were also partially supported for short visits: Markus Hunziker, Vaughn Jones, Alexei Kitaev, Burt Kostant, Hanspeter Kraft, Peter Love, Mary Beth Ruskai, Yaoyun Shi and Richard Stong. 5

  6. Shyness in Children

    MedlinePlus

    ... this site from a secured browser on the server. Please enable scripts and reload this page. Turn ... then an evaluation by a child mental-health professional would be helpful. Time to adjust Most shy ...

  7. Social Phobia

    MedlinePlus

    ... also unintentionally set an example by avoiding certain social interactions. A shy child who watches this learns that socializing is uncomfortable, distressing, and something to avoid. ... anxiety. People who constantly receive critical or disapproving ...

  8. Genetics Home Reference: SYNGAP1-related intellectual disability

    MedlinePlus

    ... TK, Ozkan ED, Shi Y, Reish NJ, Almonte AG, Miller BH, Wiltgen BJ, Miller CA, Xu X, ... qualified healthcare professional . About Selection Criteria for Links Data Files & API Site Map Subscribe Customer Support USA. ...

  9. The potential for mode conversion to rail service in Wisconsin.

    DOT National Transportation Integrated Search

    2016-07-01

    The team built upon the Wisconsin Economic Development Corporations study regarding industries that drive the Wisconsin economy, : and complemented the efforts of the Wisconsin Central Group and Wisconsin Manufacturers Commerce by geo-locating shi...

  10. Study on Climate and Grassland Fire in HulunBuir, Inner Mongolia Autonomous Region, China

    PubMed Central

    Liu, Meifang; Zhao, Jianjun; Guo, Xiaoyi; Zhang, Zhengxiang; Tan, Gang; Yang, Jihong

    2017-01-01

    Barag Youqi, Xin Barag Zuoqi, Zalantun Shi, Oroqen Zizhiqi, and Molidawa Zizhiqi; the zones with medium fire climate index are mainly distributed in Chen Barag Qi, Ewenkizu Zizhiqi, Manzhouli Shi, and Arun Qi; and the zones with lower fire climate index are mainly distributed in Genhe Shi, Ergun city, Yakeshi Shi, and Hailar Shi. The results of this study will contribute to the quantitative assessment and management of early warning and forecasting for mid-to long-term grassland fire risk in HulunBuir. PMID:28304336

  11. KSC-03pd0122

    NASA Image and Video Library

    2003-01-16

    KENNEDY SPACE CENTER, FLA. -- As billows of smoke and steam roll across the landscape, the fiery launch of Space Shuttle Columbia on mission STS-107 is reflected in nearby water. Following a flawless and uneventful countdown, liftoff occurred on-time at 10:39 a.m. EST. The 16-day research mission will include FREESTAR (Fast Reaction Experiments Enabling Science, Technology, Applications and Research) and the SHI Research Double Module (SHI/RDM), known as SPACEHAB. Experiments on the module range from material sciences to life sciences. Landing is scheduled at about 8:53 a.m. EST on Saturday, Feb. 1. This mission is the first Shuttle mission of 2003. Mission STS-107 is the 28th flight of the orbiter Columbia and the 113th flight overall in NASA's Space Shuttle program.

  12. KSC-03pd0120

    NASA Image and Video Library

    2003-01-16

    KENNEDY SPACE CENTER, FLA. -- Silhouetted against the blue Atlantic Ocean, Space Shuttle Columbia breaks free of the launch pad as it roars toward space on mission STS-107. Following a flawless and uneventful countdown, liftoff occurred on-time at 10:39 a.m. EST. The 16-day research mission will include FREESTAR (Fast Reaction Experiments Enabling Science, Technology, Applications and Research) and the SHI Research Double Module (SHI/RDM), known as SPACEHAB. Experiments on the module range from material sciences to life sciences. Landing is scheduled at about 8:53 a.m. EST on Saturday, Feb. 1. This mission is the first Shuttle mission of 2003. Mission STS-107 is the 28th flight of the orbiter Columbia and the 113th flight overall in NASA's Space Shuttle program.

  13. KSC-03pd0136

    NASA Image and Video Library

    2003-01-16

    KENNEDY SPACE CENTER, FLA. -- Spewing flames and billowing clouds of smoke across Launch Pad 39A, Space Shuttle Columbia roars toward space on mission STS-107. Following a flawless and uneventful countdown, liftoff occurred on-time at 10:39 a.m. EST. The 16-day research mission will include FREESTAR (Fast Reaction Experiments Enabling Science, Technology, Applications and Research) and the SHI Research Double Module (SHI/RDM), known as SPACEHAB. Experiments on the module range from material sciences to life sciences.. Landing of Columbia is scheduled at about 8:53 a.m. EST on Saturday, Feb. 1. This mission is the first Shuttle mission of 2003. Mission STS-107 is the 28th flight of the orbiter Columbia and the 113th flight overall in NASA's Space Shuttle program. [Photo courtesy of Scott Andrews

  14. KSC-03pd0132

    NASA Image and Video Library

    2003-01-16

    KENNEDY SPACE CENTER, FLA. -- A mirror image in nearby water reflects the perfect launch of Space Shuttle Columbia on a perfect Florida day. Following a flawless and uneventful countdown, liftoff of the Shuttle on mission STS-107 occurred on-time at 10:39 a.m. EST. The 16-day research mission will include FREESTAR (Fast Reaction Experiments Enabling Science, Technology, Applications and Research) and the SHI Research Double Module (SHI/RDM), known as SPACEHAB. Experiments on the module range from material sciences to life sciences.. Landing of Columbia is scheduled at about 8:53 a.m. EST on Saturday, Feb. 1. This mission is the first Shuttle mission of 2003. Mission STS-107 is the 28th flight of the orbiter Columbia and the 113th flight overall in NASA's Space Shuttle program.

  15. KSC-03pd0121

    NASA Image and Video Library

    2003-01-16

    KENNEDY SPACE CENTER, FLA. -- A twisting column of smoke points the way to Space Shuttle Columbia at its tip as the Shuttle hurtles toward space on mission STS-107. Following a flawless and uneventful countdown, liftoff occurred on-time at 10:39 a.m. EST. The 16-day research mission will include FREESTAR (Fast Reaction Experiments Enabling Science, Technology, Applications and Research) and the SHI Research Double Module (SHI/RDM), known as SPACEHAB. Experiments on the module range from material sciences to life sciences. Landing is scheduled at about 8:53 a.m. EST on Saturday, Feb. 1. This mission is the first Shuttle mission of 2003. Mission STS-107 is the 28th flight of the orbiter Columbia and the 113th flight overall in NASA's Space Shuttle program.

  16. KSC-03pd0129

    NASA Image and Video Library

    2003-01-16

    KENNEDY SPACE CENTER, FLA. -- Pulling free of Earth's gravity, and leaving a trail of smoke behind, Space Shuttle Columbia roars toward space on mission STS-107. Following a flawless and uneventful countdown, liftoff occurred on-time at 10:39 a.m. EST. The 16-day research mission will include FREESTAR (Fast Reaction Experiments Enabling Science, Technology, Applications and Research) and the SHI Research Double Module (SHI/RDM), known as SPACEHAB. Experiments on the module range from material sciences to life sciences.. Landing of Columbia is scheduled at about 8:53 a.m. EST on Saturday, Feb. 1. This mission is the first Shuttle mission of 2003. Mission STS-107 is the 28th flight of the orbiter Columbia and the 113th flight overall in NASA's Space Shuttle program.

  17. KSC-03pd0127

    NASA Image and Video Library

    2003-01-16

    KENNEDY SPACE CENTER, FLA. -- After a perfect launch, spectators try to catch a last glimpse of Space Shuttle Columbia, barely visible at the top end of the twisted column of smoke. Following a flawless and uneventful countdown, liftoff occurred on-time at 10:39 a.m. EST. Headed for a 16-day research mission, Columbia's crew will be taking part in more than 80 experiment, including FREESTAR (Fast Reaction Experiments Enabling Science, Technology, Applications and Research) and the SHI Research Double Module (SHI/RDM), known as SPACEHAB. Experiments on the module range from material sciences to life sciences. This mission is the first Shuttle mission of 2003. Mission STS-107 is the 28th flight of the orbiter Columbia and the 113th flight overall in NASA's Space Shuttle program.

  18. KSC-03pd0135

    NASA Image and Video Library

    2003-01-16

    KENNEDY SPACE CENTER, FLA. -- Spewing flames and billowing clouds of smoke across Launch Pad 39A, Space Shuttle Columbia roars toward space on mission STS-107. Following a flawless and uneventful countdown, liftoff occurred on-time at 10:39 a.m. EST. The 16-day research mission will include FREESTAR (Fast Reaction Experiments Enabling Science, Technology, Applications and Research) and the SHI Research Double Module (SHI/RDM), known as SPACEHAB. Experiments on the module range from material sciences to life sciences.. Landing of Columbia is scheduled at about 8:53 a.m. EST on Saturday, Feb. 1. This mission is the first Shuttle mission of 2003. Mission STS-107 is the 28th flight of the orbiter Columbia and the 113th flight overall in NASA's Space Shuttle program. [Photo courtesy of Scott Andrews

  19. KSC-03pd0134

    NASA Image and Video Library

    2003-01-16

    KENNEDY SPACE CENTER, FLA. -- Space Shuttle Columbia seems to leap from amid the trees as it roars toward space on mission STS-107. Following a flawless and uneventful countdown, liftoff occurred on-time at 10:39 a.m. EST. The 16-day research mission will include FREESTAR (Fast Reaction Experiments Enabling Science, Technology, Applications and Research) and the SHI Research Double Module (SHI/RDM), known as SPACEHAB. Experiments on the module range from material sciences to life sciences.. Landing of Columbia is scheduled at about 8:53 a.m. EST on Saturday, Feb. 1. This mission is the first Shuttle mission of 2003. Mission STS-107 is the 28th flight of the orbiter Columbia and the 113th flight overall in NASA's Space Shuttle program. [Photo courtesy of Scott Andrews

  20. KSC-03pd0112

    NASA Image and Video Library

    2003-01-16

    KENNEDY SPACE CENTER, FLA. -- Billows of white clouds of steam and smoke frame Space Shuttle Columbia as it rises above the launch tower on Launch Pad 39A on mission STS-107. Following a flawless and uneventful countdown, liftoff occurred on-time at 10:39 a.m. EST. The 16-day research mission will include FREESTAR (Fast Reaction Experiments Enabling Science, Technology, Applications and Research) and the SHI Research Double Module (SHI/RDM), known as SPACEHAB. Experiments on the module range from material sciences to life sciences. Landing is scheduled at about 8:53 a.m. EST on Saturday, Feb. 1. This mission is the first Shuttle mission of 2003. Mission STS-107 is the 28th flight of the orbiter Columbia and the 113th flight overall in NASA's Space Shuttle program.

  1. KSC-03pd0125

    NASA Image and Video Library

    2003-01-16

    KENNEDY SPACE CENTER, FLA. - All eyes in the VIP stand at KSC focus on Space Shuttle Columbia as it roars toward space on mission STS-107. Following a flawless and uneventful countdown, liftoff occurred on-time at 10:39 a.m. EST. The 16-day research mission will include FREESTAR (Fast Reaction Experiments Enabling Science, Technology, Applications and Research) and the SHI Research Double Module (SHI/RDM), known as SPACEHAB. Experiments on the module range from material sciences to life sciences.. Landing of Columbia is scheduled at about 8:53 a.m. EST on Saturday, Feb. 1. This mission is the first Shuttle mission of 2003. Mission STS-107 is the 28th flight of the orbiter Columbia and the 113th flight overall in NASA's Space Shuttle program.

  2. KSC-03pd0131

    NASA Image and Video Library

    2003-01-16

    KENNEDY SPACE CENTER, FLA. -- A mirror image in nearby water reflects the perfect launch of Space Shuttle Columbia on a perfect Florida day. Following a flawless and uneventful countdown, liftoff of the Shuttle on mission STS-107 occurred on-time at 10:39 a.m. EST. The 16-day research mission will include FREESTAR (Fast Reaction Experiments Enabling Science, Technology, Applications and Research) and the SHI Research Double Module (SHI/RDM), known as SPACEHAB. Experiments on the module range from material sciences to life sciences.. Landing of Columbia is scheduled at about 8:53 a.m. EST on Saturday, Feb. 1. This mission is the first Shuttle mission of 2003. Mission STS-107 is the 28th flight of the orbiter Columbia and the 113th flight overall in NASA's Space Shuttle program.

  3. KSC-03pd0118

    NASA Image and Video Library

    2003-01-16

    KENNEDY SPACE CENTER, FLA. - Competing with the brilliant blue sky, flames behind Space Shuttle Columbia trail a column of smoke as the Shuttle hurtles toward space on mission STS-107. Following a flawless and uneventful countdown, liftoff occurred on-time at 10:39 a.m. EST. The 16-day research mission will include FREESTAR (Fast Reaction Experiments Enabling Science, Technology, Applications and Research) and the SHI Research Double Module (SHI/RDM), known as SPACEHAB. Experiments on the module range from material sciences to life sciences. Landing is scheduled at about 8:53 a.m. EST on Saturday, Feb. 1. This mission is the first Shuttle mission of 2003. Mission STS-107 is the 28th flight of the orbiter Columbia and the 113th flight overall in NASA's Space Shuttle program.

  4. KSC-03pp0139

    NASA Image and Video Library

    2003-01-16

    KENNEDY SPACE CENTER, FLA. - Space Shuttle Columbia leaps off Launch Pad 39A and the clouds of smoke and steam as it races toward space on mission STS-107. Following a flawless and uneventful countdown, liftoff occurred on-time at 10:39 a.m. EST. The 16-day research mission includes FREESTAR (Fast Reaction Experiments Enabling Science, Technology, Applications and Research) and the SHI Research Double Module (SHI/RDM), known as SPACEHAB. Experiments on the module range from material sciences to life sciences.. Landing of Columbia is scheduled at about 8:53 a.m. EST on Saturday, Feb. 1. This mission is the first Shuttle mission of 2003. Mission STS-107 is the 28th flight of the orbiter Columbia and the 113th flight overall in NASA's Space Shuttle program.

  5. KSC-03pd0123

    NASA Image and Video Library

    2003-01-16

    KENNEDY SPACE CENTER, FLA. -- A twisting column of smoke points the way to Space Shuttle Columbia at its tip as the Shuttle hurtles toward space on mission STS-107. Following a flawless and uneventful countdown, liftoff occurred on-time at 10:39 a.m. EST. The 16-day research mission will include FREESTAR (Fast Reaction Experiments Enabling Science, Technology, Applications and Research) and the SHI Research Double Module (SHI/RDM), known as SPACEHAB. Experiments on the module range from material sciences to life sciences. Landing is scheduled at about 8:53 a.m. EST on Saturday, Feb. 1. This mission is the first Shuttle mission of 2003. Mission STS-107 is the 28th flight of the orbiter Columbia and the 113th flight overall in NASA's Space Shuttle program.

  6. KSC-03pp0140

    NASA Image and Video Library

    2003-01-16

    KENNEDY SPACE CENTER, FLA. - Space Shuttle Columbia outraces the multi-colored clouds of smoke and steam rising below it from Launch Pad 39A as it races toward space on mission STS-107. Following a flawless and uneventful countdown, liftoff occurred on-time at 10:39 a.m. EST. The 16-day research mission includes FREESTAR (Fast Reaction Experiments Enabling Science, Technology, Applications and Research) and the SHI Research Double Module (SHI/RDM), known as SPACEHAB. Experiments on the module range from material sciences to life sciences.. Landing of Columbia is scheduled at about 8:53 a.m. EST on Saturday, Feb. 1. This mission is the first Shuttle mission of 2003. Mission STS-107 is the 28th flight of the orbiter Columbia and the 113th flight overall in NASA's Space Shuttle program.

  7. KSC-03PP-0149

    NASA Technical Reports Server (NTRS)

    2003-01-01

    KENNEDY SPACE CENTER, FLA. -- STS-107 Payload Specialist Ilan Ramon, who represents the Israel Space Agency, chats with the Closeout Crew in the White Room before entering Columbia. The environmentally controlled chamber is mated to Space Shuttle Columbia for entry into the Shuttle. Ramon is the first Israeli astronaut to fly in the Shuttle. STS-107 is a mission devoted to research and will include more than 80 experiments that will study Earth and space science, advanced technology development, and astronaut health and safety. The payload on Space Shuttle Columbia includes FREESTAR (Fast Reaction Experiments Enabling Science, Technology, Applications and Research) and the SHI Research Double Module (SHI/RDM), known as SPACEHAB. Experiments on the module range from material sciences to life sciences. Liftoff is scheduled for 10:39 a.m. EST.

  8. [Health Care Insurance in France: its impact on income distribution between age and social groups].

    PubMed

    Fourcade, N; Duval, J; Lardellier, R

    2013-08-01

    Our study, based on microsimulation models, evaluates the redistributive impact of health care insurance in France on income distribution between age and social groups. This work sheds light on the debate concerning the respective role of the public health care insurance (PHI) and the private supplemental health care insurance (SHI) in France. The analysis points out that the PHI enables the lowest-income households and the pensioners a better access to health care than they would have had under a complete private SHI. Due to the progressivity of taxes, low-income households contribute less to the PHI and get higher benefits because of a weaker health. Pensioners have low contributions to public health care finance but the highest health care expenditures. Copyright © 2013 Elsevier Masson SAS. All rights reserved.

  9. Gender differences in the relationship between young children's peer-related social competence and individual differences in theory of mind.

    PubMed

    Walker, Sue

    2005-09-01

    In this study, the author examined the relationship between theory-of-mind understanding and preschool-aged children's peer-related social competence. One hundred eleven 3- to 5-year-old children (48 boys, 63 girls) participated in 2 theory-of-mind tasks designed to assess their understanding of false belief. Teachers rated children's peer-related social behavior in terms of prosocial behavior, aggressive or disruptive behavior, and shy or withdrawn behavior. Results indicated that, after controlling for age, theory-of-mind understanding significantly predicted aggressive or disruptive behavior for boys and prosocial behavior for girls. Theory-of-mind understanding also was related to lower scores of shy or withdrawn behavior for boys. Results are discussed in terms of the gender differences in the factors contributing to early peer competence.

  10. Enhancement in sensitivity of copper sulfide thin film ammonia gas sensor: Effect of swift heavy ion irradiation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sagade, Abhay Abhimanyu; Sharma, Ramphal; Department of Chemistry, Hanyang University, Sungdong-Ku, Haengdang-dong 17, Seoul 133-791

    2009-02-15

    The studies are carried out on the effect of swift heavy ion (SHI) irradiation on surface morphology and electrical properties of copper sulfide (Cu{sub x}S) thin films with three different chemical compositions (x values). The irradiation experiments have been carried out on Cu{sub x}S films with x=1.4, 1.8, and 2 by 100 MeV gold heavy ions at room temperature. These as-deposited and irradiated thin films have been used to detect ammonia gas at room temperature (300 K). The SHI irradiation treatment on x=1.4 and 1.8 copper sulfide films enhances the sensitivity of the gas sensor. The results are discussed consideringmore » high electronic energy deposition by 100 MeV gold heavy ions in a matrix of copper sulfide.« less

  11. Study of low vibration 4 K pulse tube cryocoolers

    NASA Astrophysics Data System (ADS)

    Xu, Mingyao; Nakano, Kyosuke; Saito, Motokazu; Takayama, Hirokazu; Tsuchiya, Akihiro; Maruyama, Hiroki

    2012-06-01

    Sumitomo Heavy Industries, Ltd. (SHI) has been continuously improving the efficiency and reducing the vibration of a 4 K pulse tube cryocooler. One advantage of a pulse tube cryocooler over a GM cryocooler is low vibration. In order to reduce vibration, both the displacement and the acceleration have to be reduced. The vibration acceleration can be reduced by splitting the valve unit from the cold head. One simple way to reduce vibration displacement is to increase the wall thickness of the tubes on the cylinder. However, heat conduction loss increases while the wall thickness increases. To overcome this dilemma, a novel concept, a tube with non-uniform wall thickness, is proposed. Theoretical analysis of this concept, and the measured vibration results of an SHI lowvibration pulse tube cryocooler, will be introduced in this paper.

  12. KSC-03pp0149

    NASA Image and Video Library

    2003-01-16

    KENNEDY SPACE CENTER, FLA. -- STS-107 Payload Specialist Ilan Ramon, who represents the Israel Space Agency, chats with the Closeout Crew in the White Room before entering Columbia. The environmentally controlled chamber is mated to Space Shuttle Columbia for entry into the Shuttle. Ramon is the first Israeli astronaut to fly in the Shuttle. STS-107 is a mission devoted to research and will include more than 80 experiments that will study Earth and space science, advanced technology development, and astronaut health and safety. The payload on Space Shuttle Columbia includes FREESTAR (Fast Reaction Experiments Enabling Science, Technology, Applications and Research) and the SHI Research Double Module (SHI/RDM), known as SPACEHAB. Experiments on the module range from material sciences to life sciences. Liftoff is scheduled for 10:39 a.m. EST.

  13. KSC-03pp0145

    NASA Image and Video Library

    2003-01-16

    KENNEDY SPACE CENTER, FLA. - STS-107 Mission Specialist Laurel Clark waves to a camera out of view during final preparations of her launch and entry suit in the White Room. The environmentally controlled chamber is mated to Space Shuttle Columbia for entry into the Shuttle. The hatch is seen in the background right. STS-107 is a mission devoted to research and will include more than 80 experiments that will study Earth and space science, advanced technology development, and astronaut health and safety. The payload on Space Shuttle Columbia includes FREESTAR (Fast Reaction Experiments Enabling Science, Technology, Applications and Research) and the SHI Research Double Module (SHI/RDM), known as SPACEHAB. Experiments on the module range from material sciences to life sciences. Liftoff is scheduled for 10:39 a.m. EST.

  14. KSC-03pp0148

    NASA Image and Video Library

    2003-01-16

    KENNEDY SPACE CENTER, FLA. - STS-107 Pilot William "Willie" McCool (center) gets help with his launch and entry suit from the Closeout Crew in the White Room. The environmentally controlled chamber is mated to Space Shuttle Columbia for entry into the Shuttle. In the foreground, left, is Mission Specialist David Brown. STS-107 is a mission devoted to research and will include more than 80 experiments that will study Earth and space science, advanced technology development, and astronaut health and safety. The payload on Space Shuttle Columbia includes FREESTAR (Fast Reaction Experiments Enabling Science, Technology, Applications and Research) and the SHI Research Double Module (SHI/RDM), known as SPACEHAB. Experiments on the module range from material sciences to life sciences. Liftoff is scheduled for 10:39 a.m. EST.

  15. No Grand Central stations

    NASA Astrophysics Data System (ADS)

    Carlowicz, Michael

    Reflecting on the lessons of the Kobe (1995), Mexico City (1985), Northridge (1994), and Loma Prieta (1989) earthquakes, two social scientists have proposed that societies invert the traditional way information is communicated in the hours and days after a natural disaster. Rather than the usual top-down, military-style, need-to-know approach to sharing information in the wake of a disaster, the researchers suggest that emergency communications should be decentralized into an “open access” system to serve leaders and ordinary citizens alike.

  16. Akashi-Kaikyo Bridge, Japan

    NASA Image and Video Library

    2015-08-10

    The Akashi Kaikyo Bridge in Japan has the longest central span of any suspension bridge in the world at 1991 m. The total length of the bridge is 3911 m. It links the city of Kobe on the mainland of Honshu to Iwaya on Awaji Island, crossing the busy Akashi Strait. The image was acquired April 26, 2014, covers an area of 8.1 by 11.2 km, and is located at 34.6 degrees north, 135 degrees east. http://photojournal.jpl.nasa.gov/catalog/PIA19747

  17. One new species of the subgenus Xizicus (Zangxizicus) (Orthoptera: Tettigoniidae: Meconematinae) from China.

    PubMed

    Lin, Chang Yan; Xia, Su Cai; Ming, Shi Fu

    2016-09-26

    The paper reports one new species of the tribe Meconematini, Xizicus (Zangxizicus), curvus Chang & Shi sp. nov., and supplies the character photographs of the new species and Xizicus(Zangxizicus) tibeticus Wang, Jing, Liu & Li, 2014.

  18. Bullying: It's Not OK

    MedlinePlus

    ... Prevention Listen Español Text Size Email Print Share Bullying: It's Not OK Page Content Article Body Bullying ... are shy, and generally feel helpless. Facts About Bullying Both girls and boys can be bullies. Bullies ...

  19. Leg pain

    MedlinePlus

    ... eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 81. Marcussen B, Hogrefe C, ... Medicine: Principles and Practice . 4th ed. Philadelphia, PA: Elsevier Saunders; 2015:chap 112. Shy ME. Peripheral neuropathies. ...

  20. Mononeuropathy

    MedlinePlus

    ... a nerve outside the brain and spinal cord ( peripheral neuropathy ). Mononeuropathy is most often caused by injury. Bodywide ( ... Philadelphia, PA: Elsevier; 2016:chap 107. Shy ME. Peripheral neuropathies. In: Goldman L, Schafer AI, eds. Goldman's Cecil ...

  1. Chronic inflammatory polyneuropathy

    MedlinePlus

    ... to nerves outside the brain or spinal cord ( peripheral neuropathy ). Polyneuropathy means several nerves are involved. CIDP often ... Philadelphia, PA: Elsevier; 2016:chap 107. Shy ME. Peripheral neuropathies. In: Goldman L, Schafer AI, eds. Goldman's Cecil ...

  2. Results of a Prospective Study of Acute Coronary Syndrome Hospitalization After Enactment of a Smoking Ban in Public Places in Hyogo Prefecture - Comparison With Gifu, a Prefecture Without a Public Smoking Ban.

    PubMed

    Sato, Yukihito; Minatoguchi, Shinya; Nishigaki, Kazuhiko; Hirata, Ken-Ichi; Masuyama, Tohru; Furukawa, Yutaka; Uematsu, Masaaki; Yoshikawa, Junichi; Otsuji, Satoru; Iida, Mami; Fujiwara, Hisayoshi

    2016-11-25

    Hyogo Prefecture is the 2nd prefecture in Japan, after Kanagawa, to enact a ban with penal code on smoking in public places, although the restriction is partial.Methods and Results:This study included consecutive patients with acute coronary syndrome (ACS) who were admitted to 33 major hospitals in the Hyogo District during the 12 months before implementation of the legislation and during the 24 months thereafter. Consecutive patients with ACS from Gifu Prefecture who were admitted to 20 major hospitals were enrolled as geographical controls. The number of ACS admissions did not change from the years 2012-2015 in both Hyogo District (1,774 in the pre-year, 1,784 in the 1st year, and 1,720 in the 2nd year) and Gifu Prefecture (1,226 in the pre-year, 1,174 in the 1st year, and 1,206 in the 2nd year). However, a clear reduction was observed in the subanalysis for Kobe City (895 in the preceding year, 830 (-7.3%) in the 1st year, and 792 (-11.5%) in the 2nd year), where adherence to the smoking ban was higher than in other Hyogo districts. The primary endpoint did not show a significant change. However, the subanalysis showed a significant decrease in ACS admissions in Kobe City. These results suggest that ACS reduction may depend on the degree of adherence to a smoking ban. (Circ J 2016; 80: 2528-2532).

  3. Can Hybrid Educational Activities of Team and Problem Based Learning Program be Effective for Japanese Medical Students?

    PubMed

    Iwata, Kentaro; Doi, Asako

    2017-11-10

    The purpose of this study is to investigate the medical students'perceptions of the Hybrid Educational Activities between team based learning (TBL) and problem based learning (PBL) Program (HEATAPP), a novel educational program that combines characteristics of PBL and TBL. A five-day HEATAPP on infectious diseases was provided to 4th year medical students at Kobe University School of Medicine, Kobe, Japan. After the program, a focus group discussion was held among 6 medical students who participated in HEATAPP. We qualitatively analyzed the recorded data to delineate the effectiveness of, and the perceptions on, HEATAPP. Some students considered HEATAPP being effective as an active learning, and in developing questions. However, some students found active learning difficult to execute, since they were so familiar with passive learning such as lectures and examinations. They also found it difficult to identify important points by reading authentic textbooks on given issues, particularly English textbooks. Even though active learning and group discussion are underscored as important in medicine, some Japanese medical students may be reluctant to shift towards these since they are so used to passive learning since childhood. English language is another barrier to active learning. The introduction of active learning in the earlier stages of education might be an effective solution. Teachers at medical schools in Japan should be mindful of the students'potentially negative attitudes towards active learning, which is claimed to be successful in western countries.

  4. Study on comparison of special moment frame steel structure (SMF) and base isolation special moment frame steel structure (BI-SMF) in Indonesia

    NASA Astrophysics Data System (ADS)

    Setiawan, Jody; Nakazawa, Shoji

    2017-10-01

    This paper discusses about comparison of seismic response behaviors, seismic performance and seismic loss function of a conventional special moment frame steel structure (SMF) and a special moment frame steel structure with base isolation (BI-SMF). The validation of the proposed simplified estimation method of the maximum deformation of the base isolation system by using the equivalent linearization method and the validation of the design shear force of the superstructure are investigated from results of the nonlinear dynamic response analysis. In recent years, the constructions of steel office buildings with seismic isolation system are proceeding even in Indonesia where the risk of earthquakes is high. Although the design code for the seismic isolation structure has been proposed, there is no actual construction example for special moment frame steel structure with base isolation. Therefore, in this research, the SMF and BI-SMF buildings are designed by Indonesian Building Code which are assumed to be built at Padang City in Indonesia. The material of base isolation system is high damping rubber bearing. Dynamic eigenvalue analysis and nonlinear dynamic response analysis are carried out to show the dynamic characteristics and seismic performance. In addition, the seismic loss function is obtained from damage state probability and repair cost. For the response analysis, simulated ground accelerations, which have the phases of recorded seismic waves (El Centro NS, El Centro EW, Kobe NS and Kobe EW), adapted to the response spectrum prescribed by the Indonesian design code, that has, are used.

  5. Klinefelter Syndrome

    MedlinePlus

    ... Enlarged breast tissue (gynecomastia) Weak bones Low energy levels Tendency to be shy and sensitive Difficulty expressing thoughts and feelings or socializing Problems with reading, writing, spelling or math Men Low sperm count or no sperm Small ...

  6. From Beginners to Successes: Six Life Lessons

    ERIC Educational Resources Information Center

    Gendong, Shi

    2018-01-01

    Shi Gendong wrote this essay in response to the topic "Even Laureates Were Beginners Once: Lessons Learned Along the Way," which was the title of the Laureate Panel at the Kappa Delta Pi Convocation in October 2017.

  7. Neuralgia

    MedlinePlus

    ... 2016:chap 107. Scadding JW, Koltzenberg M. Painful peripheral neuropathies. In: McMahon SB, Koltzenburg M, Tracey I, Turk ... PA: Elsevier Saunders; 2013:chap 65. Shy ME. Peripheral neuropathies. In: Goldman L, Schafer AI, eds. Goldman's Cecil ...

  8. Radial nerve dysfunction

    MedlinePlus

    ... Philadelphia, PA: Elsevier; 2016:chap 107. Shy ME. Peripheral neuropathies. In: Goldman L, Schafer AI, eds. Goldman's Cecil ... Read more Hand Injuries and Disorders Read more Peripheral Nerve Disorders Read more A.D.A.M., Inc. is ...

  9. Efficient Performance of Electrostatic Spray-Deposited TiO2 Blocking Layers in Dye-Sensitized Solar Cells after Swift Heavy Ion Beam Irradiation.

    PubMed

    Sudhagar, P; Asokan, K; Jung, June Hyuk; Lee, Yong-Gun; Park, Suil; Kang, Yong Soo

    2011-12-01

    A compact TiO2 layer (~1.1 μm) prepared by electrostatic spray deposition (ESD) and swift heavy ion beam (SHI) irradiation using oxygen ions onto a fluorinated tin oxide (FTO) conducting substrate showed enhancement of photovoltaic performance in dye-sensitized solar cells (DSSCs). The short circuit current density (Jsc = 12.2 mA cm(-2)) of DSSCs was found to increase significantly when an ESD technique was applied for fabrication of the TiO2 blocking layer, compared to a conventional spin-coated layer (Jsc = 8.9 mA cm(-2)). When SHI irradiation of oxygen ions of fluence 1 × 10(13) ions/cm(2) was carried out on the ESD TiO2, it was found that the energy conversion efficiency improved mainly due to the increase in open circuit voltage of DSSCs. This increased energy conversion efficiency seems to be associated with improved electronic energy transfer by increasing the densification of the blocking layer and improving the adhesion between the blocking layer and the FTO substrate. The adhesion results from instantaneous local melting of the TiO2 particles. An increase in the electron transport from the blocking layer may also retard the electron recombination process due to the oxidized species present in the electrolyte. These findings from novel treatments using ESD and SHI irradiation techniques may provide a new tool to improve the photovoltaic performance of DSSCs.

  10. Efficient Performance of Electrostatic Spray-Deposited TiO2 Blocking Layers in Dye-Sensitized Solar Cells after Swift Heavy Ion Beam Irradiation

    PubMed Central

    2011-01-01

    A compact TiO2 layer (~1.1 μm) prepared by electrostatic spray deposition (ESD) and swift heavy ion beam (SHI) irradiation using oxygen ions onto a fluorinated tin oxide (FTO) conducting substrate showed enhancement of photovoltaic performance in dye-sensitized solar cells (DSSCs). The short circuit current density (Jsc = 12.2 mA cm-2) of DSSCs was found to increase significantly when an ESD technique was applied for fabrication of the TiO2 blocking layer, compared to a conventional spin-coated layer (Jsc = 8.9 mA cm-2). When SHI irradiation of oxygen ions of fluence 1 × 1013 ions/cm2 was carried out on the ESD TiO2, it was found that the energy conversion efficiency improved mainly due to the increase in open circuit voltage of DSSCs. This increased energy conversion efficiency seems to be associated with improved electronic energy transfer by increasing the densification of the blocking layer and improving the adhesion between the blocking layer and the FTO substrate. The adhesion results from instantaneous local melting of the TiO2 particles. An increase in the electron transport from the blocking layer may also retard the electron recombination process due to the oxidized species present in the electrolyte. These findings from novel treatments using ESD and SHI irradiation techniques may provide a new tool to improve the photovoltaic performance of DSSCs. PMID:27502653

  11. Child shyness and peer likeability: The moderating role of pragmatics and vocabulary.

    PubMed

    Cheung, Hoi Shan; Elliott, John M

    2017-11-01

    The association between shyness and children's likeability by peers was examined, with pragmatic difficulty and receptive and expressive vocabularies as moderators. Participants were 164 preschoolers (72 boys, 92 girls) between 52 and 79 months old in Singapore. A cross-informant methodology was used, with peers and teachers contributing to separate peer likeability ratings. The findings highlighted a conceptual distinction between peer- and teacher-rated likeability by peers. For the latter only, a 3-way interaction involving shyness, vocabulary, and pragmatic difficulty was found, indicating that for shy children with low vocabulary scores, those who experienced less pragmatic difficulty tended to be seen by teachers as more well-liked by peers than those with more pragmatic difficulty. This suggests that pragmatic skills may serve a protective function especially for shy children with poor vocabulary skills. Statement of contribution What is already known on this subject? Child shyness is related to poorer peer acceptance and social competence Expressive vocabulary and pragmatic competence each has a buffering effect for shy children What the present study adds? Shyness is related to poorer peer likeability as assessed by teachers Shyness is unrelated to peer likeability as assessed by same- or different-sex peers Pragmatic skills buffer the effects of teacher-rated shyness only for children with poor receptive and expressive vocabularies The buffering effect of language ability is shown in a multilingual educational context. © 2017 The British Psychological Society.

  12. Willingness to pay for health insurance among the elderly population in Germany.

    PubMed

    Bock, Jens-Oliver; Heider, Dirk; Matschinger, Herbert; Brenner, Hermann; Saum, Kai-Uwe; Haefeli, Walter E; König, Hans-Helmut

    2016-03-01

    All elderly Germans are legally obliged to have health insurance. About 90 % of this population are members of social health insurances (SHI) whose premiums are generally income-related and independent of health status. For most of these members, holding social health insurance is mandatory. As a consequence, genuine information about preferences for health insurance is not available. The aim of this study was therefore to determine and analyze the willingness to pay (WTP) for health insurance among elderly Germans. Data from a population-based 8-year follow-up of a large cohort study conducted in the Saarland, Germany was used. Participants aged 57-84 years passed a geriatric assessment and responded to a health economic questionnaire. Individuals' WTP was elicited based on a contingent valuation method with a payment card. Mean monthly WTP per capita for health insurance amounted to €260. This corresponded to about 20% of individual disposable income. Regression analyses showed that WTP increased significantly with higher income, male gender, higher educational level, and privately insured status. In contrast, neither increasing morbidity level nor higher individual health care costs influenced WTP significantly. The relatively large extent of average WTP for health insurance indicates that the elderly would probably accept higher contributions to SHI rather than policy efforts to reduce contributions. The identified determinants of WTP might indicate that elderly generally approve the principle of solidarity of the SHI with contributions depending on income rather than morbidity.

  13. Model of wet chemical etching of swift heavy ions tracks

    NASA Astrophysics Data System (ADS)

    Gorbunov, S. A.; Malakhov, A. I.; Rymzhanov, R. A.; Volkov, A. E.

    2017-10-01

    A model of wet chemical etching of tracks of swift heavy ions (SHI) decelerated in solids in the electronic stopping regime is presented. This model takes into account both possible etching modes: etching controlled by diffusion of etchant molecules to the etching front, and etching controlled by the rate of a reaction of an etchant with a material. Olivine ((Mg0.88Fe0.12)2SiO4) crystals were chosen as a system for modeling. Two mechanisms of chemical activation of olivine around the SHI trajectory are considered. The first mechanism is activation stimulated by structural transformations in a nanometric track core, while the second one results from neutralization of metallic atoms by generated electrons spreading over micrometric distances. Monte-Carlo simulations (TREKIS code) form the basis for the description of excitations of the electronic subsystem and the lattice of olivine in an SHI track at times up to 100 fs after the projectile passage. Molecular dynamics supplies the initial conditions for modeling of lattice relaxation for longer times. These simulations enable us to estimate the effects of the chemical activation of olivine governed by both mechanisms. The developed model was applied to describe chemical activation and the etching kinetics of tracks of Au 2.1 GeV ions in olivine. The estimated lengthwise etching rate (38 µm · h-1) is in reasonable agreement with that detected in the experiments (24 µm · h-1).

  14. Abortion: its contribution to maternal mortality.

    PubMed

    Kwast, B E

    1992-03-01

    Every year between 100,000 and 200,000 women die from illicit abortion. In this paper the magnitude of the problem is described, those most at risk are identified and methods of preventing unwanted pregnancy are suggested. It is argued that midwives have a major role to play in family planning counselling and the provision of contraceptive services. Midwives can also reduce maternal mortality by resuscitating women when emergencies arise from incomplete abortion. This paper is based on one originally given at the ICM/WHO/UNICEF pre-congress workshop is Kobe, Japan, October 1990.

  15. Regeneration, morphogenesis and self-organization.

    PubMed

    Goldman, Daniel

    2014-07-01

    The RIKEN Center for Developmental Biology in Kobe, Japan, hosted a meeting entitled 'Regeneration of Organs: Programming and Self-Organization' in March, 2014. Scientists from across the globe met to discuss current research on regeneration, organ morphogenesis and self-organization - and the links between these fields. A diverse range of experimental models and organ systems was presented, and the speakers aptly illustrated the unique power of each. This Meeting Review describes the major advances reported and themes emerging from this exciting meeting. © 2014. Published by The Company of Biologists Ltd.

  16. Ulnar nerve dysfunction

    MedlinePlus

    ... Philadelphia, PA: Elsevier; 2016:chap 107. Shy ME. Peripheral neuropathies. In: Goldman L, Schafer AI, eds. Goldman's Cecil ... Editorial team. Hand Injuries and Disorders Read more Peripheral Nerve Disorders Read more NIH MedlinePlus Magazine Read more A. ...

  17. Autonomic neuropathy

    MedlinePlus

    ... Philadelphia, PA: Elsevier; 2016:chap 107. Shy ME. Peripheral neuropathies. In: Goldman L, Schafer AI, eds. Goldman-Cecil ... Editorial team. Autonomic Nervous System Disorders Read more Peripheral Nerve Disorders Read more NIH MedlinePlus Magazine Read more A. ...

  18. KSC-03pd0138

    NASA Image and Video Library

    2003-01-16

    KENNEDY SPACE CENTER, FLA. - Seeming to be perched on twin columns of fire, Space Shuttle Columbia leaps off Launch Pad 39A and races toward space on missions STS-107. Following a flawless and uneventful countdown, liftoff occurred on-time at 10:39 a.m. EST. The 16-day research mission will include FREESTAR (Fast Reaction Experiments Enabling Science, Technology, Applications and Research) and the SHI Research Double Module (SHI/RDM), known as SPACEHAB. Experiments on the module range from material sciences to life sciences.. Landing of Columbia is scheduled at about 8:53 a.m. EST on Saturday, Feb. 1. This mission is the first Shuttle mission of 2003. Mission STS-107 is the 28th flight of the orbiter Columbia and the 113th flight overall in NASA's Space Shuttle program. [Photo courtesy of Scott Andrews

  19. KSC-03pd0137

    NASA Image and Video Library

    2003-01-16

    KENNEDY SPACE CENTER, FLA. - In this view, Space Shuttle Columbia is almost dwarfed by the rolling clouds of smoke and steam across Launch Pad 39A. Following a flawless and uneventful countdown, launch of Columbia on mission STS-107 occurred on-time at 10:39 a.m. EST. The 16-day research mission will include FREESTAR (Fast Reaction Experiments Enabling Science, Technology, Applications and Research) and the SHI Research Double Module (SHI/RDM), known as SPACEHAB. Experiments on the module range from material sciences to life sciences.. Landing of Columbia is scheduled at about 8:53 a.m. EST on Saturday, Feb. 1. This mission is the first Shuttle mission of 2003. Mission STS-107 is the 28th flight of the orbiter Columbia and the 113th flight overall in NASA's Space Shuttle program. [Photo courtesy of Scott Andrews

  20. KSC-03pd0133

    NASA Image and Video Library

    2003-01-16

    KENNEDY SPACE CENTER, FLA. -- As billows of smoke and steam roll across the landscape, the fiery launch of Space Shuttle Columbia on mission STS-107 is reflected in nearby water. Following a flawless and uneventful countdown, liftoff occurred on-time at 10:39 a.m. EST. The 16-day research mission will include FREESTAR (Fast Reaction Experiments Enabling Science, Technology, Applications and Research) and the SHI Research Double Module (SHI/RDM), known as SPACEHAB. Experiments on the module range from material sciences to life sciences. Landing is scheduled at about 8:53 a.m. EST on Saturday, Feb. 1. This mission is the first Shuttle mission of 2003. Mission STS-107 is the 28th flight of the orbiter Columbia and the 113th flight overall in NASA's Space Shuttle program. [Photo courtesy of Scott Andrews

  1. Optional deductibles in social health insurance systems: findings from Germany.

    PubMed

    Pütz, Claudia; Hagist, Christian

    2006-12-01

    A fundamental aspect of the German health insurance system is the principle of solidarity. At the same time, it is possible for certain socio-economic groups to opt out of the otherwise compulsory system. To determine whether rates incorporating deductibles are compatible with the principles of solidarity and have the ability to heighten the appeal of statutory health insurance (SHI) funds compared with private health insurance companies, Germany's third largest SHI fund, Techniker Krankenkasse, implemented a pilot scheme involving the use of deductibles. Preliminary scientific evaluations of the pilot scheme indicate three main results for these deductibles: Firstly, they are compatible with the principles of solidarity in the statutory health insurance system; secondly, they provide an effective means of preventing defection to private health insurance companies and thirdly, they reduced the volume of insurance claims (moral hazard).

  2. STS-107 Payload Specialist Ilan Ramon at SPACEHAB during training

    NASA Technical Reports Server (NTRS)

    2002-01-01

    KENNEDY SPACE CENTER, FLA. - STS-107 Payload Specialist Ilan Ramon, from Israel, trains on equipment at SPACEHAB, Cape Canaveral, Fla. STS-107 is a research mission. The primary payload is the first flight of the SHI Research Double Module (SHI/RDM). The experiments range from material sciences to life sciences (many rats). Also part of the payload is the Fast Reaction Experiments Enabling Science, Technology, Applications and Research (FREESTAR) that incorporates eight high priority secondary attached shuttle experiments: Mediterranean Israeli Dust Experiment (MEIDEX), Shuttle Ozone Limb Sounding Experiment (SOLSE-2), Student Tracked Atmospheric Research Satellite for Heuristic International Networking Experiment (STARSHINE), Critical Viscosity of Xenon-2 (CVX-2), Solar Constant Experiment-3 (SOLOCON-3), Prototype Synchrotron Radiation Detector (PSRD), Low Power Transceiver (LPT), and Collisions Into Dust Experiment -2 (COLLIDE-2). STS-107 is scheduled to launch in July 2002

  3. STS-107 Mission Specialist Kalpana Chawla at SPACEHAB during training

    NASA Technical Reports Server (NTRS)

    2002-01-01

    KENNEDY SPACE CENTER, FLA. -- STS-107 Mission Specialist Kalpana Chawla scans paperwork for equipment at SPACEHAB, Cape Canaveral, Fla., during crew training. STS-107 is a research mission. The primary payload is the first flight of the SHI Research Double Module (SHI/RDM). The experiments range from material sciences to life sciences (many rats). Also part of the payload is the Fast Reaction Experiments Enabling Science, Technology, Applications and Research (FREESTAR) that incorporates eight high priority secondary attached shuttle experiments: Mediterranean Israeli Dust Experiment (MEIDEX), Shuttle Ozone Limb Sounding Experiment (SOLSE-2), Student Tracked Atmospheric Research Satellite for Heuristic International Networking Experiment (STARSHINE), Critical Viscosity of Xenon-2 (CVX-2), Solar Constant Experiment-3 (SOLOCON-3), Prototype Synchrotron Radiation Detector (PSRD), Low Power Transceiver (LPT), and Collisions Into Dust Experiment -2 (COLLIDE-2). STS-107 is scheduled to launch in July 2002

  4. STS-107 Mission Specialist Kalpana Chawla at SPACEHAB during training

    NASA Technical Reports Server (NTRS)

    2002-01-01

    KENNEDY SPACE CENTER, FLA. - STS-107 Mission Specialist Kalpana Chawla looks over equipment at SPACEHAB, Cape Canaveral, Fla., during crew training. STS-107 is a research mission. The primary payload is the first flight of the SHI Research Double Module (SHI/RDM). The experiments range from material sciences to life sciences (many rats). Also part of the payload is the Fast Reaction Experiments Enabling Science, Technology, Applications and Research (FREESTAR) that incorporates eight high priority secondary attached shuttle experiments: Mediterranean Israeli Dust Experiment (MEIDEX), Shuttle Ozone Limb Sounding Experiment (SOLSE-2), Student Tracked Atmospheric Research Satellite for Heuristic International Networking Experiment (STARSHINE), Critical Viscosity of Xenon-2 (CVX-2), Solar Constant Experiment-3 (SOLOCON-3), Prototype Synchrotron Radiation Detector (PSRD), Low Power Transceiver (LPT), and Collisions Into Dust Experiment -2 (COLLIDE-2). STS-107 is scheduled to launch in July 2002

  5. KSC-02pd0052

    NASA Image and Video Library

    2002-01-10

    KENNEDY SPACE CENTER, FLA. - STS-107 Payload Specialist Ilan Ramon, from Israel, trains on equipment at SPACEHAB, Cape Canaveral, Fla. STS-107 is a research mission. The primary payload is the first flight of the SHI Research Double Module (SHI/RDM). The experiments range from material sciences to life sciences (many rats). Also part of the payload is the Fast Reaction Experiments Enabling Science, Technology, Applications and Research (FREESTAR) that incorporates eight high priority secondary attached shuttle experiments: Mediterranean Israeli Dust Experiment (MEIDEX), Shuttle Ozone Limb Sounding Experiment (SOLSE-2), Student Tracked Atmospheric Research Satellite for Heuristic International Networking Experiment (STARSHINE), Critical Viscosity of Xenon-2 (CVX-2), Solar Constant Experiment-3 (SOLOCON-3), Prototype Synchrotron Radiation Detector (PSRD), Low Power Transceiver (LPT), and Collisions Into Dust Experiment -2 (COLLIDE-2). STS-107 is scheduled to launch in July 2002

  6. KSC01pd1885

    NASA Image and Video Library

    2001-12-19

    KENNEDY SPACE CENTER, FLA. -- At SPACEHAB, Cape Canaveral, Fla., Commander Rick Husband works with an experiment that will be part of the mission. STS-107 is a research mission. The primary payload is the first flight of the SHI Research Double Module (SHI/RDM). The experiments range from material sciences to life sciences (many rats). Also part of the payload is the Fast Reaction Experiments Enabling Science, Technology, Applications and Research (FREESTAR) that incorporates eight high priority secondary attached shuttle experiments: Mediterranean Israeli Dust Experiment (MEIDEX), Shuttle Ozone Limb Sounding Experiment (SOLSE-2), Student Tracked Atmospheric Research Satellite for Heuristic International Networking Experiment (STARSHINE), Critical Viscosity of Xenon-2 (CVX-2), Solar Constant Experiment-3 (SOLOCON-3), Prototype Synchrotron Radiation Detector (PSRD), Low Power Transceiver (LPT), and Collisions Into Dust Experiment -2 (COLLIDE-2). STS-107 is scheduled to launch in July 2002

  7. KSC-02pd0053

    NASA Image and Video Library

    2002-01-10

    KENNEDY SPACE CENTER, FLA. -- STS-107 Mission Specialist Kalpana Chawla scans paperwork for equipment at SPACEHAB, Cape Canaveral, Fla., during crew training. STS-107 is a research mission. The primary payload is the first flight of the SHI Research Double Module (SHI/RDM). The experiments range from material sciences to life sciences (many rats). Also part of the payload is the Fast Reaction Experiments Enabling Science, Technology, Applications and Research (FREESTAR) that incorporates eight high priority secondary attached shuttle experiments: Mediterranean Israeli Dust Experiment (MEIDEX), Shuttle Ozone Limb Sounding Experiment (SOLSE-2), Student Tracked Atmospheric Research Satellite for Heuristic International Networking Experiment (STARSHINE), Critical Viscosity of Xenon-2 (CVX-2), Solar Constant Experiment-3 (SOLOCON-3), Prototype Synchrotron Radiation Detector (PSRD), Low Power Transceiver (LPT), and Collisions Into Dust Experiment -2 (COLLIDE-2). STS-107 is scheduled to launch in July 2002

  8. KSC-03pd0126

    NASA Image and Video Library

    2003-01-16

    KENNEDY SPACE CENTER, FLA. - The VIP stand at KSC is filled with not only friends and families of the astronauts, but also representatives of Israel who came to support the first Israeli to fly on a Shuttle, Ilan Ramon. As a payload specialist, Ramon will take part in some of the research on the mission. He is also a colonel in the Israel Air Force. The 16-day research mission will include FREESTAR (Fast Reaction Experiments Enabling Science, Technology, Applications and Research) and the SHI Research Double Module (SHI/RDM), known as SPACEHAB. Experiments on the module range from material sciences to life sciences. This mission is the first Shuttle mission of 2003. Mission STS-107 is the 28th flight of the orbiter Columbia and the 113th flight overall in NASA's Space Shuttle program.

  9. Study finds increases in risk of leukemias related to treatment

    Cancer.gov

    A new study describes the pattern of risk for chemotherapy-related acute myeloid leukemia among adult cancer survivors over the past three decades who have previously been treated with chemotherapy for other cancers. These patterns coincide with major shi

  10. MYC RNAi-Pt Combination Nanotherapy for Metastatic Prostate Cancer Treatment

    DTIC Science & Technology

    2016-10-01

    cell line-based allograft tumors by the hybrid NPs. 15. SUBJECT TERMS Nanotechnology , nanoparticle, siRNA delivery, platinum, MYC, prostate cancer...co-investigators (Dr. Srinivasan Yegnasubramanian from JHU and Dr. Jinjun Shi from BWH/HMS). 3 2. KEYWORDS Nanotechnology , lipid, polymer

  11. A study comparing the hypnotic efficacies and residual effects on actual driving performance of midazolam 15 mg, triazolam 0.5 mg, temazepam 20 mg and placebo in shiftworkers on night duty

    DOT National Transportation Integrated Search

    1988-11-01

    The purpose of the study was to determine the hypnotic efficacy and residual effects of three hypnotics administered for the treatment of transient insomnia in the day-sleep of rotating shift workers. The average duration of day-sleep in rotating shi...

  12. TRANSPORT AND DEPOSITION OF NANO-SIZE PARTICLES IN THE UPPER HUMAN RESPIRATORY AIRWAYS

    EPA Science Inventory

    TRANSPORT AND DEPOSITION OF NANO-SIZE PARTICLES IN THE UPPER HUMAN RESPIRATORY AIRWAYS. Zhe Zhang*, Huawei Shi, Clement Kleinstreuer, Department of Mechanical and Aerospace Engineering, North Carolina State University, Raleigh, NC 27695-7910; Chong S. Kim, National Health and En...

  13. Evaluation of hydraulic cement concrete overlays placed on three pavements in Virginia.

    DOT National Transportation Integrated Search

    2000-08-01

    Three hydraulic cement concrete pavement overlays were placed in the summer of 1995 at three locations in Virginia. Two of the overlays were placed on continuously reinforced concrete pavement to prevent spalling caused by a shy cover over the reinfo...

  14. Taxonomic synopsis of the subtribe Physoderina (Coleoptera, Carabidae, Lebiini), with species revisions of eight genera

    PubMed Central

    Shi, Hongliang; Zhou, Hongzhang; Liang, Hongbin

    2013-01-01

    Abstract Ten genera of Physoderina from the Oriental Region are diagnosed and described, and twenty six species representing eight genera (Paraphaea Bates, Anchista Nietner, Metallanchista gen. n., Diamella nom. n., Allocota Motschulsky, Orionella Jedlička, Endynomena Chaudoir and Dasiosoma Britton (Oriental species only)) are revised. Keys to genera and species are provided, along with distribution maps, habitus images, photographs of the name-bearing types, and illustrations of male and female genitalia of available species. The female internal reproductive system is illustrated for fourteen species. Two genera, Anchista and Taicona, previously placed in Calleidina, are moved into Physoderina. One new genus is described: Metallanchista, gen. n. (type species Metallanchista laticollis, sp. n.). Two new generic synonyms are proposed: Taicona Bates, 1873, junior synonym of Allocota Motschulsky, 1859; Teradaia Habu, 1979a, junior synonym of Dasiosoma Britton, 1937. A new generic replacement name is proposed: Diamella, nom. n. for Diamella Jedlička, 1952 (junior homonym of Diamella Gude, 1913). The status of Paraphaea Bates, 1873 is resurrected from synonym of Anchista Nietner, 1856. Five new species are described: Paraphaea minor Shi & Liang, sp. n. (Hoa-Binh, Tonkin, Vietnam), Anchista pilosa Shi & Liang, sp. n. (Chikkangalur, Bangalore, India), Metallanchista laticollis Shi & Liang, sp. n. (PhaTo env., Chumphon prov., Thailand), Allocota bicolor Shi & Liang, sp. n. (Dengga to Mafengshan, Ruili, Yunnan, China), Dasiosoma quadraticolle Shi & Liang, sp. n. (Menglun Botanical Garden, Yunnan, China). Fourteen new combinations are proposed: Paraphaea binotata (Dejean, 1825), comb. n. from Anchista; Paraphaea formosana (Jedlička, 1946), comb. n. from Anchista; Paraphaea philippinensis (Jedlička, 1935b), comb. n. from Allocota; Metallanchista perlaeta (Kirschenhofer, 1994), comb. n. from Allocota; Physodera andrewesi (Jedlička, 1934), comb. n. from Allocota; Diamella

  15. Enhancing fish Underwater Visual Census to move forward assessment of fish assemblages: An application in three Mediterranean Marine Protected Areas

    PubMed Central

    Thiriet, Pierre; Di Franco, Antonio; Francour, Patrice

    2017-01-01

    Monitoring fish assemblages is needed to assess whether Marine Protected Areas (MPAs) are meeting their conservation and fisheries management goals, as it allows one to track the progress of recovery of exploited species and associated communities. Underwater Visual Census techniques (UVC) are used to monitor fish assemblages in MPAs. UVCs should be adapted to fish abundance, body-size and behaviour, which can strongly affect fish detectability. In Mediterranean subtidal habitats, however, UVC strip transects of one surface area (25x5 m2) are commonly used to survey the whole fish assemblage, from large shy fish to small crypto-benthic fish. Most high trophic level predators (HTLPs) are large shy fish which rarely swim close to divers and, consequently, their abundance may be under-estimated with commonly used transects. Here, we propose an improvement to traditional transect surveys to better account for differences in behaviour among and within species. First, we compared the effectiveness of combining two transect surface areas (large: 35x20 m2; medium: 25x5 m2) in quantifying large, shy fish within and outside Mediterranean MPAs. We identified species-specific body-size thresholds defining a smaller and a larger size class better sampled by medium and large transects respectively. Combining large and medium transects provided more accurate biomass and species richness estimates for large, shy species than using medium transects alone. We thus combined the new approach with two other transect surface areas commonly used to survey crypto-benthic (10x1 m2) and necto-benthic (25x5 m2) species in order to assess how effectively MPAs protection the whole fish assemblage. We verified that MPAs offer significant protection for HTLPs, their response in terms of biomass and density increase in MPAs was always higher in magnitude than other functional groups. Inside MPAs, the contribution of HTLP reached >25% of total fish biomass, against < 2% outside MPAs. Surveys with

  16. Enhancing fish Underwater Visual Census to move forward assessment of fish assemblages: An application in three Mediterranean Marine Protected Areas.

    PubMed

    Prato, Giulia; Thiriet, Pierre; Di Franco, Antonio; Francour, Patrice

    2017-01-01

    Monitoring fish assemblages is needed to assess whether Marine Protected Areas (MPAs) are meeting their conservation and fisheries management goals, as it allows one to track the progress of recovery of exploited species and associated communities. Underwater Visual Census techniques (UVC) are used to monitor fish assemblages in MPAs. UVCs should be adapted to fish abundance, body-size and behaviour, which can strongly affect fish detectability. In Mediterranean subtidal habitats, however, UVC strip transects of one surface area (25x5 m2) are commonly used to survey the whole fish assemblage, from large shy fish to small crypto-benthic fish. Most high trophic level predators (HTLPs) are large shy fish which rarely swim close to divers and, consequently, their abundance may be under-estimated with commonly used transects. Here, we propose an improvement to traditional transect surveys to better account for differences in behaviour among and within species. First, we compared the effectiveness of combining two transect surface areas (large: 35x20 m2; medium: 25x5 m2) in quantifying large, shy fish within and outside Mediterranean MPAs. We identified species-specific body-size thresholds defining a smaller and a larger size class better sampled by medium and large transects respectively. Combining large and medium transects provided more accurate biomass and species richness estimates for large, shy species than using medium transects alone. We thus combined the new approach with two other transect surface areas commonly used to survey crypto-benthic (10x1 m2) and necto-benthic (25x5 m2) species in order to assess how effectively MPAs protection the whole fish assemblage. We verified that MPAs offer significant protection for HTLPs, their response in terms of biomass and density increase in MPAs was always higher in magnitude than other functional groups. Inside MPAs, the contribution of HTLP reached >25% of total fish biomass, against < 2% outside MPAs. Surveys with

  17. One new species of the genus Acosmetura (Tettigoniidae: Meconematinae) from Hubei, China.

    PubMed

    Wang, Ping; Bian, Xun; Shi, Fu Ming

    2016-09-28

    One new species of the genus Acosmetura (Tettigoniidae: Meconematinae) is described, namely Acosmetura trigentis Wang, Bian & Shi sp. nov. from Hubei, China. In addition, morphological photographs and a distribution map are provided. The examined specimens are deposited in the Museum of Hebei University.

  18. A MAPPING BASED ON PHYSICO-CHEMICAL FEATURES: LESSONS LEARNT

    EPA Science Inventory

    The ban on animal testing of cosmetic products for systemic toxicity in Europe is foreseen in 2013. Several research programs involving the public and private sectors have been initiated with the aim of fulfilling regulatory requirements and complying with this transformative shi...

  19. Multiple System Atrophy with Orthostatic Hypotension (Shy-Drager Syndrome)

    MedlinePlus

    ... Strategy Current Research Research Funded by NINDS Basic Neuroscience Clinical Research Translational Research Research at NINDS Focus ... Diversity Resources Jobs at NINDS Director, Division of Neuroscience Director, NIH BRAIN Initiative® Health Scientist Administrator Channels ...

  20. The Nature and Future of Shi’ite Fundamentalism

    DTIC Science & Technology

    1990-03-28

    initially consisted of an exhaustive compilation of the memories of those who had known Mohammed, or knew others who had known him, sometimes several... memories , orally transmitted. The work of writing down the Hadith did not begin until some fifty years after the death of the Prophet, and two hundred...ways. By chanting religious tracts they eventually achieve a state of self- hypnosis , during which they may beat their own chests, slash their heads

  1. Regional Implications of Shi’a Revival in Iraq

    DTIC Science & Technology

    2004-01-01

    From the marshes of southern Iraq to the ghettoes of Karachi, the Shi‘a have been the underdogs —oppressed and marginalized by Sunni ruling regimes and...former with “true” Is- lam—and their governments as its defenders—and branding the latter as obscurantist extremism. They dismissed Khomeini as Shi‘a... branding his vitriol against the House of Saud in the 1980s as fitna (illegitimate rebellion and sowing of disunity) against the Muslim community.7

  2. Sunni and Shi’a Terrorism: Differences that Matter

    DTIC Science & Technology

    2008-12-29

    of the Alawite variant, Ayatollah Khomeini quickly adopted the fledgling  Hezbollah movement by  financing  it, arming it and providing it religious...thought provoking, they are  ultimately unconvincing. At best, the evidence suggests that Shi’a expatriate communities tend to  finance  terrorist‐linked...Shi’a‐extremists in Lebanon. This makes them akin to Irish expatriate  communities  financing  Irish Republican Army terror against Great Britain in the

  3. Sleep and the Price of Plasticity: From Synaptic and Cellular Homeostasis to Memory Consolidation and Integration

    PubMed Central

    Tononi, Giulio; Cirelli, Chiara

    2014-01-01

    Summary Sleep is universal, tightly regulated, and its loss impairs cognition. But why does the brain need to disconnect from the environment for hours every day? The synaptic homeostasis hypothesis (SHY) proposes that sleep is the price the brain pays for plasticity. During a waking episode, learning statistical regularities about the current environment requires strengthening connections throughout the brain. This increases cellular needs for energy and supplies, decreases signal-to-noise ratios, and saturates learning. During sleep, spontaneous activity renormalizes net synaptic strength and restores cellular homeostasis. Activity-dependent down-selection of synapses can also explain the benefits of sleep on memory acquisition, consolidation, and integration. This happens through the off-line, comprehensive sampling of statistical regularities incorporated in neuronal circuits over a lifetime. This review considers the rationale and evidence for SHY and points to open issues related to sleep and plasticity. PMID:24411729

  4. KSC01pd1881

    NASA Image and Video Library

    2001-12-19

    KENNEDY SPACE CENTER, FLA. -- STS-107 Commander Rick Husband and Mission Specialist Laurel Clark learn to work with mission-related equipment at SPACEHAB, Cape Canaveral, Fla. STS-107 is a research mission. The primary payload is the first flight of the SHI Research Double Module (SHI/RDM). The experiments range from material sciences to life sciences (many rats). Also part of the payload is the Fast Reaction Experiments Enabling Science, Technology, Applications and Research (FREESTAR) that incorporates eight high priority secondary attached shuttle experiments: Mediterranean Israeli Dust Experiment (MEIDEX), Shuttle Ozone Limb Sounding Experiment (SOLSE-2), Student Tracked Atmospheric Research Satellite for Heuristic International Networking Experiment (STARSHINE), Critical Viscosity of Xenon-2 (CVX-2), Solar Constant Experiment-3 (SOLOCON-3), Prototype Synchrotron Radiation Detector (PSRD), Low Power Transceiver (LPT), and Collisions Into Dust Experiment -2 (COLLIDE-2). STS-107 is scheduled to launch in July 2002

  5. KSC01pd1882

    NASA Image and Video Library

    2001-12-19

    KENNEDY SPACE CENTER, FLA. - STS-107 Payload Specialist Ilan Ramon, from Israel, pauses during an experiment at SPACEHAB, Cape Canaveral, Fla., to talk with Mission Specialist Laurel Clark. STS-107 is a research mission. The primary payload is the first flight of the SHI Research Double Module (SHI/RDM). The experiments range from material sciences to life sciences (many rats). Also part of the payload is the Fast Reaction Experiments Enabling Science, Technology, Applications and Research (FREESTAR) that incorporates eight high priority secondary attached shuttle experiments: Mediterranean Israeli Dust Experiment (MEIDEX), Shuttle Ozone Limb Sounding Experiment (SOLSE-2), Student Tracked Atmospheric Research Satellite for Heuristic International Networking Experiment (STARSHINE), Critical Viscosity of Xenon-2 (CVX-2), Solar Constant Experiment-3 (SOLOCON-3), Prototype Synchrotron Radiation Detector (PSRD), Low Power Transceiver (LPT), and Collisions Into Dust Experiment -2 (COLLIDE-2). STS-107 is scheduled to launch in July 2002.

  6. KSC01pd1883

    NASA Image and Video Library

    2001-12-19

    KENNEDY SPACE CENTER, FLA. - - STS-107 Payload Specialist Ilan Ramon, from Israel, works on an experiment at SPACEHAB, Cape Canaveral, Fla. With him is Mission Specialist Laurel Clark. STS-107 is a research mission. The primary payload is the first flight of the SHI Research Double Module (SHI/RDM). The experiments range from material sciences to life sciences (many rats). Also part of the payload is the Fast Reaction Experiments Enabling Science, Technology, Applications and Research (FREESTAR) that incorporates eight high priority secondary attached shuttle experiments: Mediterranean Israeli Dust Experiment (MEIDEX), Shuttle Ozone Limb Sounding Experiment (SOLSE-2), Student Tracked Atmospheric Research Satellite for Heuristic International Networking Experiment (STARSHINE), Critical Viscosity of Xenon-2 (CVX-2), Solar Constant Experiment-3 (SOLOCON-3), Prototype Synchrotron Radiation Detector (PSRD), Low Power Transceiver (LPT), and Collisions Into Dust Experiment -2 (COLLIDE-2). STS-107 is scheduled to launch in July 2002

  7. Sleep and the price of plasticity: from synaptic and cellular homeostasis to memory consolidation and integration.

    PubMed

    Tononi, Giulio; Cirelli, Chiara

    2014-01-08

    Sleep is universal, tightly regulated, and its loss impairs cognition. But why does the brain need to disconnect from the environment for hours every day? The synaptic homeostasis hypothesis (SHY) proposes that sleep is the price the brain pays for plasticity. During a waking episode, learning statistical regularities about the current environment requires strengthening connections throughout the brain. This increases cellular needs for energy and supplies, decreases signal-to-noise ratios, and saturates learning. During sleep, spontaneous activity renormalizes net synaptic strength and restores cellular homeostasis. Activity-dependent down-selection of synapses can also explain the benefits of sleep on memory acquisition, consolidation, and integration. This happens through the offline, comprehensive sampling of statistical regularities incorporated in neuronal circuits over a lifetime. This Perspective considers the rationale and evidence for SHY and points to open issues related to sleep and plasticity. Copyright © 2014 Elsevier Inc. All rights reserved.

  8. KSC-03pd0110

    NASA Image and Video Library

    2003-01-16

    KENNEDY SPACE CENTER, FLA. -- The STS-107 crew heads for the Astrovan and a ride to Launch Pad 39A for liftoff. From left to right are Payload Commander Michael Anderson, Mission Specialist David Brown, Payload Specialist Ilan Ramon, Mission Specialists Laurel Clark and Kalpana Chawla, Mission Commandaer Rick Husband and Pilot William "Willie" McCool. Ramon is the first astronaut from Israel to fly on a Shuttle. The 16-day mission is devoted to research and will include more than 80 experiments that will study Earth and space science, advanced technology development, and astronaut health and safety. The payload on Space Shuttle Columbia includes FREESTAR (Fast Reaction Experiments Enabling Science, Technology, Applications and Research) and the SHI Research Double Module (SHI/RDM), known as SPACEHAB. Experiments on the module range from material sciences to life sciences. Liftoff is scheduled for 10:39 a.m. EST. [Photo courtesy of Scott Andrews

  9. Brief report: Perceptions of social withdrawal during emerging adulthood in Lagos, Nigeria.

    PubMed

    Bowker, Julie C; Ojo, Adesola Adebusola; Bowker, Matthew H

    2016-02-01

    The study of social withdrawal subtypes is no longer limited to Western societies but has extended to non-Western countries, such as China. This study considers, for the first time, social withdrawal subtypes in an African country (Nigeria) by examining emerging adults' (N = 151; 54% female; Mage = 19.92 years, SD = 2.54) perceptions, attitudes, and responses to shy, unsociable, and socially competent behaviors. Results revealed that Nigerian emerging adults perceived significant differences between shy, unsociable, and socially competent behavior in several ways incommensurate with participants of previous studies conducted in North America, Europe, and China. Findings highlight the diversity of social meanings attached to social withdrawal in non-Western societies, and point to the need for additional research on social withdrawal and its perception in Africa. Copyright © 2015 The Foundation for Professionals in Services for Adolescents. Published by Elsevier Ltd. All rights reserved.

  10. Measuring attachment to life in old age: the Portuguese version of the Positive Valuation of Life Scale (Positive VOL).

    PubMed

    Araújo, Lia; Ribeiro, Oscar; Teixeira, Laetitia; Azevedo, Maria João; Jopp, Daniela S; Rott, Christoph; Paúl, Constança

    2015-10-01

    This study aims to present the psychometric properties of the Portuguese version of the Positive Valuation of Life Scale (Lawton et al. in J Aging Ment Healt 13:3-31, 2001). Sample included 207 community-dwelling elders (129 women; M Age = 77.2 years, SD = 7.5). The data collection included the translated and adapted Portuguese version of Positive Valuation of Life Scale, Life Satisfaction Index Z, Meaning in Life Questionnaire and Geriatric Depression Scale. From exploratory factor analysis, two factors emerged, existential beliefs and perceived control, explaining 49 % of the total variance. Both factors were positively related with meaning in life and life satisfaction and negatively related with depression (p < 0.05). The values obtained for internal consistency for the total scale and for each subscale were good (α > 0.75). The Portuguese version of Positive VOL Scale represents a reliable and valid measure to capture the subjective experience of attachment to one's life. The two-factor structure is an update to Lawton's previous work and in line with findings obtained in the USA (Dennis et al. in What is valuation of life for frail community-dwelling older adults: factor structure and criterion validity of the VOL, Thomas Jefferson University, Center for Applied Research on Aging and Health Research, 2005) and Japan (Nakagawa et al. in Shinrigaku Kenkyu 84:37-46, 2013). Future research is required to investigate VOL predictors and the potential changes toward the end of the life span.

  11. Purification/annealing of graphene with 100-MeV Ag ion irradiation

    PubMed Central

    2014-01-01

    Studies on interaction of graphene with radiation are important because of nanolithographic processes in graphene-based electronic devices and for space applications. Since the electronic properties of graphene are highly sensitive to the defects and number of layers in graphene sample, it is desirable to develop tools to engineer these two parameters. We report swift heavy ion (SHI) irradiation-induced annealing and purification effects in graphene films, similar to that observed in our studies on fullerenes and carbon nanotubes (CNTs). Raman studies after irradiation with 100-MeV Ag ions (fluences from 3 × 1010 to 1 × 1014 ions/cm2) show that the disorder parameter α, defined by ID/IG ratio, decreases at lower fluences but increases at higher fluences beyond 1 × 1012 ions/cm2. This indicates that SHI induces annealing effects at lower fluences. We also observe that the number of graphene layers is reduced at fluences higher than 1 × 1013 ions/cm2. Using inelastic thermal spike model calculations, we estimate a radius of 2.6 nm for ion track core surrounded by a halo extending up to 11.6 nm. The transient temperature above the melting point in the track core results in damage, whereas lower temperature in the track halo is responsible for annealing. The results suggest that SHI irradiation fluence may be used as one of the tools for defect annealing and manipulation of the number of graphene layers. PACS 60.80.x; 81.05.ue PMID:24636520

  12. Cost-effectiveness of tiotropium versus salmeterol: the POET-COPD trial.

    PubMed

    Hoogendoorn, Martine; Al, Maiwenn J; Beeh, Kai-Michael; Bowles, David; Graf von der Schulenburg, J Matthias; Lungershausen, Juliane; Monz, Brigitta U; Schmidt, Hendrik; Vogelmeier, Claus; Rutten-van Mölken, Maureen P M H

    2013-03-01

    The aim of this study was to perform a 1-yr trial-based cost-effectiveness analysis (CEA) of tiotropium versus salmeterol followed by a 5-yr model-based CEA. The within-trial CEA, including 7,250 patients with moderate to very severe chronic obstructive pulmonary disease (COPD), was performed alongside the 1-yr international randomised controlled Prevention of Exacerbations with Tiotropium (POET)-COPD trial comparing tiotropium with salmeterol regarding the effect on exacerbations. Main end-points of the trial-based analysis were costs, number of exacerbations and exacerbation days. The model-based analysis was conducted to extrapolate results to 5 yrs and to calculate quality-adjusted life years (QALYs). 1-yr costs per patient from the German statutory health insurance (SHI) perspective and the societal perspective were €126 (95% uncertainty interval (UI) €55-195) and €170 (95% UI €77-260) higher for tiotropium, respectively. The annual number of exacerbations was 0.064 (95% UI 0.010-0.118) lower for tiotropium, leading to a reduction in exacerbation-related costs of €87 (95% UI €19-157). The incremental cost-effectiveness ratio was €1,961 per exacerbation avoided from the SHI perspective and €2,647 from the societal perspective. In the model-based analyses, the 5-yr costs per QALY were €3,488 from the SHI perspective and €8,141 from the societal perspective. Tiotropium reduced exacerbations and exacerbation-related costs, but increased total costs. Tiotropium can be considered cost-effective as the resulting cost-effectiveness ratios were below commonly accepted willingness-to-pay thresholds.

  13. Development of a new knock-in mouse model and evaluation of pharmacological activities of lusutrombopag, a novel, nonpeptidyl small-molecule agonist of the human thrombopoietin receptor c-Mpl.

    PubMed

    Yoshida, Hiroshi; Yamada, Hajime; Nogami, Wataru; Dohi, Keiji; Kurino-Yamada, Tomomi; Sugiyama, Koji; Takahashi, Koji; Gahara, Yoshinari; Kitaura, Motoji; Hasegawa, Minoru; Oshima, Itsuki; Kuwabara, Kenji

    2018-03-01

    Lusutrombopag (S-888711), an oral small-molecule thrombopoietin receptor (TPOR) agonist, has gained first approval as a drug to treat thrombocytopenia of chronic liver disease in patients undergoing elective invasive procedures in Japan. Preclinical studies were performed to evaluate its efficacy against megakaryopoiesis and thrombopoiesis. To investigate the proliferative activity and efficacy of megakaryocytic colony formation via human TPOR, lusutrombopag was applied to cultured human c-Mpl-expressing Ba/F3 (Ba/F3-hMpl) cells and human bone marrow-derived CD34-positive cells, respectively. Lusutrombopag caused a robust increase in Ba/F3-hMpl cells by activating pathways in a manner similar to that of thrombopoietin and induced colony-forming units-megakaryocyte and polyploid megakaryocytes in human CD34-positive cells. Because lusutrombopag has high species specificity for human TPOR, there was no suitable experimental animal model for drug evaluation, except for immunodeficient mouse-based xenograft models. Therefore, a novel genetically modified knock-in mouse, TPOR-Ki/Shi, was developed by replacing mouse Mpl with human-mouse chimera Mpl. In TPOR-Ki/Shi mice, lusutrombopag significantly increased circulating platelets in a dose-dependent manner during 21-day repeated oral administration. Histopathological study of the TPOR-Ki/Shi mice on day 22 also revealed a significant increase in megakaryocytes in the bone marrow. These results indicate that lusutrombopag acts on human TPOR to upregulate differentiation and proliferation of megakaryocytic cells, leading to platelet production. Copyright © 2018 ISEH – Society for Hematology and Stem Cells. Published by Elsevier Inc. All rights reserved.

  14. Protracted storage of CR chondrules in a region of the disk transparent to galactic cosmic rays

    NASA Astrophysics Data System (ADS)

    Roth, Antoine S. G.; Metzler, Knut; Baumgartner, Lukas P.; Hofmann, Beda A.; Leya, Ingo

    2017-10-01

    Renazzo-type carbonaceous (CR) chondrites are accretionary breccias that formed last. As such they are ideal samples to study precompaction exposures to cosmic rays. Here, we present noble gas data for 24 chondrules and 3 dark inclusion samples (DIs) from Shişr 033 (CR2). The meteorite was selected based on the absence of implanted solar wind noble gases and an anomalous oxygen isotopic composition of the DIs; the oxygen isotopes match those in CV3 and CO3 chondrites. Our samples contain variable mixtures of galactic cosmic ray (GCR)-produced cosmogenic noble gases and trapped noble gases of presolar origin. Remarkably, all chondrules have cosmogenic 3He and 21Ne concentrations up to 4.3 and 7.1 times higher than the DIs, respectively. We derived an average 3He-21Ne cosmic ray exposure (CRE) age for Shişr 033 of 2.03 ± 0.20 Ma (2 SD) and excesses in cosmogenic 3He and 21Ne in chondrules (relative to the DIs) in the range (in 10-8 cm3STP/g) 3.99-7.76 and 0.94-1.71, respectively. Assuming present-day GCR flux density, the excesses translate into average precompaction 3He-21Ne CRE ages of 3.1-27.3 Ma depending on the exposure geometry. The data can be interpreted assuming a protracted storage of a single chondrule generation prior to the final assembly of the Shişr 033 parent body in a region of the disk transparent to GCRs.

  15. A novel approach for detecting heat waves: the Standardized Heat-Wave Index.

    NASA Astrophysics Data System (ADS)

    Cucchi, Marco; Petitta, Marcello; Calmanti, Sandro

    2016-04-01

    Extreme temperatures have an impact on the energy balance of any living organism and on the operational capabilities of critical infrastructures. The ability to capture the occurrence of extreme temperature events is therefore an essential property of a multi-hazard extreme climate indicator. In this paper we introduce a new index for the detection of such extreme temperature events called SHI (Standardized Heat-Wave Index), developed in the context of XCF project for the construction of a multi-hazard extreme climate indicator (ECI). SHI is a probabilistic index based on the analysis of maximum daily temperatures time series; it is standardized, enabling comparisons overs space/time and with other indices, and it is capable of describing both extreme cold and hot events. Given a particular location, SHI is constructed using the time series of local maximum daily temperatures with the following procedure: three-days cumulated maximum daily temperatures are assigned to each day of the time series; probabilities of occurrence in the same months the reference days belong to are computed for each of the previous calculated values; such probability values are thus projected on a standard normal distribution, obtaining our standardized indices. In this work we present results obtained using NCEP Reanalysis dataset for air temperature at sigma 0.995 level, which timespan ranges from 1948 to 2014. Given the specific framework of this work, the geographical focus of this study is limited to the African continent. We present a validation of the index by showing its use for monitoring heat-waves under different climate regimes.

  16. Drosophila rolling blackout displays lipase domain-dependent and -independent endocytic functions downstream of dynamin.

    PubMed

    Vijayakrishnan, Niranjana; Phillips, Scott E; Broadie, Kendal

    2010-12-01

    Drosophila temperature-sensitive rolling blackout (rbo(ts) ) mutants display a total block of endocytosis in non-neuronal cells and a weaker, partial defect at neuronal synapses. RBO is an integral plasma membrane protein and is predicted to be a serine esterase. To determine if lipase activity is required for RBO function, we mutated the catalytic serine 358 to alanine in the G-X-S-X-G active site, and assayed genomic rescue of rbo mutant non-neuronal and neuronal phenotypes. The rbo(S358A) mutant is unable to rescue rbo null 100% embryonic lethality, indicating that the lipase domain is critical for RBO essential function. Likewise, the rbo(S358A) mutant cannot provide any rescue of endocytic blockade in rbo(ts) Garland cells, showing that the lipase domain is indispensable for non-neuronal endocytosis. In contrast, rbo(ts) conditional paralysis, synaptic transmission block and synapse endocytic defects are all fully rescued by the rbo(S358A) mutant, showing that the RBO lipase domain is dispensable in neuronal contexts. We identified a synthetic lethal interaction between rbo(ts) and the well-characterized dynamin GTPase conditional shibire (shi(ts1)) mutant. In both non-neuronal cells and neuronal synapses, shi(ts1); rbo(ts) phenocopies shi(ts1) endocytic defects, indicating that dynamin and RBO act in the same pathway, with dynamin functioning upstream of RBO. We conclude that RBO possesses both lipase domain-dependent and scaffolding functions with differential requirements in non-neuronal versus neuronal endocytosis mechanisms downstream of dynamin GTPase activity. © 2010 John Wiley & Sons A/S.

  17. Community intervention to increase neighborhood social network among Japanese older adults.

    PubMed

    Harada, Kazuhiro; Masumoto, Kouhei; Katagiri, Keiko; Fukuzawa, Ai; Chogahara, Makoto; Kondo, Narihiko; Okada, Shuichi

    2018-03-01

    Strengthening neighborhood social networks is important for promoting health among older adults. However, effective intervention strategies aimed at increasing older adults' social networks have not yet been established. The present study examined whether a university-led community intervention that provided communication opportunities could increase older Japanese adults' neighborhood social networks. The present study used a quasi-experimental design. Before the intervention, using postal mail, we carried out a baseline questionnaire survey that was sent to all people living in the Tsurukabuto community aged ≥60 years (n = 1769), of whom 1068 responded. For the community intervention, 18 event-based programs were provided over the course of 1 year at Kobe University. Academic staff at Kobe University organized all the programs. During the program, social interactions among participants were promoted. A follow-up survey was distributed to those who responded to the baseline survey, and 710 individuals answered the question about their participation in the intervention programs (138 respondents were participants, 572 were non-participants). The neighborhood social network was measured in both the baseline and follow-up surveys. Analysis of covariance showed that the changes in neighborhood social network among participants in the program was significantly higher than the changes among non-participants (P = 0.046) after adjusting for the baseline score of social network. The present study found that participants of the intervention expanded their neighborhood social network, but non-participants did not. This finding shows that community interventions using university resources could increase older adults' neighborhood social networks. Geriatr Gerontol Int 2018; 18: 462-469. © 2017 Japan Geriatrics Society.

  18. Rocket Experiment on Construction of Huge Transmitting Antenna for the SPS Using Furoshiki Satellite System with Robots

    NASA Astrophysics Data System (ADS)

    Kaya, N.; Iwashita, M.; Nakasuka, S.; Summerer, L.; Mankins, J.

    2004-12-01

    Construction technology of huge structures is essential for the future space development as well as the Solar Power Satellite (SPS). The SPS needs huge antennas to transmit the generated electric power toward the ground, while the huge antenna have many useful applications in space as well as on the ground, for example, telecommunication for cellular phones, radars for remote sensing, navigation and observation, and so on. A parabola antenna was mostly used for the space antenna. However, it is very difficult for the larger parabola antenna to keep accuracy of the reflectors and the beam control, because the surfaces of the reflectors are mechanically supported and controlled. The huge space antenna with flexible and ultra-light structures is essential and necessary for the future applications. An active phased array antenna is more suitable and promising for the huge flexible antenna than the parabola antenna. We are proposing to apply the Furoshiki satellite [1] with robots for construction of the huge structures. While a web is deployed using the Furoshiki satellite in the same size of the huge antenna, all of the antenna elements crawl on the web with their own legs toward their allocated locations. We are verifying the deployment concept of the Furoshiki satellite using a sounding rocket with robots crawling on the deployed web. The robots are internationally being developed by NASA, ESA and Kobe University. The paper describes the concept of the crawling robot developed by Kobe University as well as the plan of the rocket experiment.

  19. Personality Characteristics and Self-Concept of Preservice Teachers Related to Their Pupil Control Orientation.

    ERIC Educational Resources Information Center

    Halpin, Glennelle; And Others

    1982-01-01

    In a study of teacher trainees' personality characteristics related to pupil control, humanistically oriented educators tended to be emotionally stable, expedient, positive, imaginative, venturesome, relaxed and had high self-concepts. Authoritarian educators were more affected by feelings, conscientious, sober, practical, shy, reserved, tense and…

  20. Interfacing the NRL 1-D High Vertical Resolution Aerosol Model with COAMPS

    DTIC Science & Technology

    2006-09-30

    model integrated with mesoscale meterological data to study marine boundary layer aerosol dynamics, J. Geophys. Res., in press, 2006. Hoppel, W. A...W.A. Hoppel, J.J. Shi: A one-dimensional sectional aerosol model integrated with mesoscale meterological data to study marine boundary layer aerosol

  1. The Separate and Cumulative Effects of TBI and PTSD on Cognitive Function and Emotional Control

    DTIC Science & Technology

    2009-04-01

    CADDIE 80. SHY 80. BABY 80. HATRED 81. BOMB 81. TENANT 81. BUILDING 81. JOYFUL 81. SLIME 82. WMD 82. NFL 82. TOWER...82. SONG 82. FRAUD 83. BASRA 83. PARTISAN 83. HORSE 83. PLEASURE 83. MOLD 84. GUN 84. REDECORATE 84. SLUSH 84. COMEDY

  2. Kashmir Dispute: Significance of Its Early Resolution

    DTIC Science & Technology

    2010-03-01

    However, when it comes to bilateral negotiations, India shies away from any concrete 18 discussion by rigidly anchoring itself to the stated position...concerned that it can trigger nuclear conflagration in the region, with far – reaching devastating consequences.146 The second reason alluding to

  3. Using Solution-Focused Intervention for Behavioral Problems in an Inclusive Classroom.

    ERIC Educational Resources Information Center

    Quigney, Theresa A.; Studer, Jeannine R.

    1999-01-01

    Solution-focused intervention deviates from using negative labels (angry, aggressive, or shy) to describe misbehaving students, and reframes behavior descriptions more positively. Four steps (goal setting, looking for exceptions, visualizing a new life story, and practicing the desired behaviors) are vital to facilitating positive behavior…

  4. Disaster Relief and Crisis Intervention with Deaf Communities: Lessons Learned from the Japanese Deaf Community.

    PubMed

    Takayama, Kota

    2017-01-01

    During natural disasters and crises, the deaf and hard of hearing community might not have full accessibility to all of the information shared with the larger hearing community. This could be due to the lack of awareness among social work professionals about these cultural and linguistic needs of this minority population. The purpose of this article is to explore the challenges faced by the deaf community and to discuss culturally and linguistically appropriate crisis intervention and mobilization to natural disaster situations based on the experiences of the Japanese deaf communities affected by the Kobe and Tohoku earthquakes.

  5. The Effectiveness of the Behavioural Training for Preschool Children

    ERIC Educational Resources Information Center

    Koglin, Ute; Petermann, Franz

    2011-01-01

    This study investigated the short-term effects of behavioural training for preschool children. The goals of this programme were to reduce disruptive behaviour as well as shy and withdrawn behaviour, and to promote social-emotional competencies. In young children, insufficient emotional competencies and difficulties concerning adequate conflict…

  6. The Shock and Vibration Digest. Volume 17. Number 6

    DTIC Science & Technology

    1985-06-01

    Australia 3032 Friction Intl. J. Impact Engrg., Z (2), pp 151-167 E. Marui , S. Kato (1984), 14 figs, I table, 17 refs Gifu Univ., 1-1, Yanagido, Gifu-shi 501...Martinez-Sanchez............... 1153 * Jensen, J.J ................. 1094 Marui , F ............... 1202 Jery, B........................ 1073 Marulo,F

  7. Teaching Race and Social Justice at a Predominantly White Institution

    ERIC Educational Resources Information Center

    Bauer, Kelly; Clancy, Kelly

    2018-01-01

    At our predominantly white university, students often shy away from controversial conversations. How can the classroom encourage students to value and engage in potentially explosive conversations? We develop a concept of "empathic scaffolding" to articulate an approach that integrates diversity and inclusion into the classroom. Empathic…

  8. Community Screening for Preschool Child Inhibition to Offer the "Cool Little Kids" Anxiety Prevention Programme

    ERIC Educational Resources Information Center

    Beatson, Ruth M.; Bayer, Jordana K.; Perry, Alexandra; Mathers, Megan; Hiscock, Harriet; Wake, Melissa; Beesley, Kate; Rapee, Ronald M.

    2014-01-01

    Temperamental inhibition has been identified as a key risk factor for childhood anxiety and internalizing problems. An efficacious early prevention programme for shy/inhibited children has been developed; however, accurate, efficient and acceptable screening is needed to support wider implementation. We explore community screening options in the…

  9. Chinese Cultural Schema of Education: Implications for Communication between Chinese Students and Australian Educators

    ERIC Educational Resources Information Center

    Hui, Leng

    2005-01-01

    Education in China, in its various forms and levels, is widely conceptualised as integrating the cultivation of "human souls" with the provision of students with knowledge. The English word "education" is "jiao yu" in Chinese, which means "teaching [and] cultivating". The analogy "shi nian shu mu, bai…

  10. Swift heavy ion induced modifications in optical and electrical properties of cadmium selenide thin films

    NASA Astrophysics Data System (ADS)

    Choudhary, Ritika; Chauhan, Rishi Pal

    2017-07-01

    The modification in various properties of thin films using high energetic ion beam is an exciting area of basic and applied research in semiconductors. In the present investigations, cadmium selenide (CdSe) thin films were deposited on ITO substrate using electrodeposition technique. To study the swift heavy ion (SHI) induced effects, the deposited thin films were irradiated with 120 MeV heavy Ag9+ ions using pelletron accelerator facility at IUAC, New Delhi, India. Structural phase transformation in CdSe thin film from metastable cubic phase to stable hexagonal phase was observed after irradiation leading to decrease in the band gap from 2.47 eV to 2.12 eV. The phase transformation was analyzed through X-ray diffraction patterns. During SHI irradiation, Generation of high temperature and pressure by thermal spike along the trajectory of incident ions in the thin films might be responsible for modification in the properties of thin films.[Figure not available: see fulltext.

  11. Express yourself: bold individuals induce enhanced morphological defences

    PubMed Central

    Hulthén, Kaj; Chapman, Ben B.; Nilsson, P. Anders; Hollander, Johan; Brönmark, Christer

    2014-01-01

    Organisms display an impressive array of defence strategies in nature. Inducible defences (changes in morphology and/or behaviour within a prey's lifetime) allow prey to decrease vulnerability to predators and avoid unnecessary costs of expression. Many studies report considerable interindividual variation in the degree to which inducible defences are expressed, yet what underlies this variation is poorly understood. Here, we show that individuals differing in a key personality trait also differ in the magnitude of morphological defence expression. Crucian carp showing risky behaviours (bold individuals) expressed a significantly greater morphological defence response when exposed to a natural enemy when compared with shy individuals. Furthermore, we show that fish of different personality types differ in their behavioural plasticity, with shy fish exhibiting greater absolute plasticity than bold fish. Our data suggest that individuals with bold personalities may be able to compensate for their risk-prone behavioural type by expressing enhanced morphological defences. PMID:24335987

  12. Spectroscopic investigations upon 100MeV oxygen ions irradiation on polyaniline and poly-o-toluidine

    NASA Astrophysics Data System (ADS)

    Patil, Harshada K.; Deshmukh, Megha A.; Bodkhe, Gajanan A.; Asokan, K.; Shirsat, Mahendra D.

    2018-05-01

    Conducting polymers are the materials been extensively studied in the field of organic devise applications. The extended π-orbital which enables electron to move from one to another end of polymer made it flexible in tailoring different properties and therefore are known to be the considerably attractive materials. Here in this report Polyaniline (PANI) and Poly-o-toluidine (PoT) the derivative of PANI where one hydrogen atom of main polymer chain is substituted with the methyl group are studied upon irradiation with 100MeV oxygen ions irradiation at different fluences. PANI and PoT consist of interesting properties viz. electrochemical and optical properties, moderate conductivity, as well as environmental stability, may be applicable to the chemical sensing applications. Swift Heavy Ions (SHI) irradiation is the exclusively applied tool in detrimental modifications of solid materials. The effects of SHI irradiation on PANI and PoT were studied using UV - Vis spectroscopy and Raman spectroscopy. The band gap studies were done with Tauc plot calculations.

  13. [Verification of the double dissociation model of shyness using the implicit association test].

    PubMed

    Fujii, Tsutomu; Aikawa, Atsushi

    2013-12-01

    The "double dissociation model" of shyness proposed by Asendorpf, Banse, and Mtücke (2002) was demonstrated in Japan by Aikawa and Fujii (2011). However, the generalizability of the double dissociation model of shyness was uncertain. The present study examined whether the results reported in Aikawa and Fujii (2011) would be replicated. In Study 1, college students (n = 91) completed explicit self-ratings of shyness and other personality scales. In Study 2, forty-eight participants completed IAT (Implicit Association Test) for shyness, and their friends (n = 141) rated those participants on various personality scales. The results revealed that only the explicit self-concept ratings predicted other-rated low praise-seeking behavior, sociable behavior and high rejection-avoidance behavior (controlled shy behavior). Only the implicit self-concept measured by the shyness IAT predicted other-rated high interpersonal tension (spontaneous shy behavior). The results of this study are similar to the findings of the previous research, which supports generalizability of the double dissociation model of shyness.

  14. Sex differences in a shoaling-boldness behavioral syndrome, but no link with aggression.

    PubMed

    Way, Gregory P; Kiesel, Alexis L; Ruhl, Nathan; Snekser, Jennifer L; McRobert, Scott P

    2015-04-01

    A behavioral syndrome is observed in a population when specific behaviors overlap at the individual level in different contexts. Here, we explore boldness and aggression personality spectra, the repeatability of shoaling, and possible associated correlations between the behaviors in a population of lab-reared zebrafish (Danio rerio). Our findings describe a sex-specific boldness-shoaling behavioral syndrome, as a link between boldness and shoaling behaviors is detected. The results indicate that bold males are likely to have a stronger shoaling propensity than shy males for unfamiliar conspecifics. Conversely, bold females are more likely to shoal than shy females, but only when presented with heterospecific individuals. Additionally, aggression does not correlate with boldness or shoaling propensity for either sex. A positive relationship between boldness and shoaling that differs by sex is contrary to most of the present literature, but could help to explain population dynamics and may also have evolutionary implications. Copyright © 2015 Elsevier B.V. All rights reserved.

  15. Compulsive buying and borderline personality symptomatology.

    PubMed

    Sansone, Randy A; Chang, Joy; Jewell, Bryan; Sellbom, Martin; Bidwell, Mark

    2013-04-01

    In this study, the authors investigated the relationship between compulsive buying and borderline personality disorder (BPD) symptomatology--two disorders possibly linked through impulsivity. Using a survey methodology in a cross-sectional consecutive sample of nonemergent female outpatients from an obstetrics/gynecology clinic, the authors assessed compulsive buying with the compulsive buying scale (CBS) and BPD symptomatology through the BPD scale of the personality diagnostic questionnaire-4 (PDQ-4) and the self-harm Inventory (SHI). In this sample, 8% of Caucasian women and 9% of African-American women scored positively for compulsive buying. The correlations between scores on the CBS and the PDQ-4 and SHI were 0.43 and 0.41, respectively-both statistically significant at the p < .001 level. Compared to Caucasian women, African-American women demonstrated statistical associations between the BPD measures and the CBS scale scores that were significantly larger. Findings suggest relationships between compulsive buying and BPD, particularly among African-American women.

  16. The Relationship Between Online Video Game Involvement and Gaming-Related Friendships Among Emotionally Sensitive Individuals

    PubMed Central

    Domahidi, Emese; Quandt, Thorsten

    2014-01-01

    Abstract Some researchers believe that online gaming spaces can be socially accommodating environments for socially inhibited individuals, such as the socially inept, socially anxious, or shy. While previous research has examined, and found, significant links between these populations and online video game play, it remains unknown to what extent these spaces are contributing to tangible social benefits for the socially inhibited. The current study addresses this question by evaluating the link between gaming-related friendships and shyness, as quantified by emotional sensitivity. Drawing from a representative sample of German game players, the results indicate that emotionally sensitive players are using online gaming spaces differently from their less emotionally sensitive counterparts and reporting tangible differences in their in-game friendship networks. This suggests that online games hold the potential to be socially advantageous for shy individuals by allowing them to overcome their traditional social difficulties and generate new friendships as well as strengthen old ones. PMID:24660878

  17. On the self-serving function of social anxiety: shyness as a self-handicapping strategy.

    PubMed

    Snyder, C R; Smith, T W; Augelli, R W; Ingram, R E

    1985-04-01

    We tested the hypothesis that socially anxious or shy individuals use their anxiety symptoms as a strategy to control attributions made about their performances in social-evaluative settings (i.e., self-handicapping strategies). Specifically, we predicted that trait-socially anxious or shy persons would report more symptoms of social anxiety in an evaluative setting in which anxiety or shyness could serve as an excuse for poor performance than would individuals in (a) an evaluative setting in which shyness was precluded as an excuse or (b) a nonevaluative setting. Furthermore, we predicted that this self-protective pattern of symptom reporting would not occur for individuals who were not trait-socially anxious because these persons would not commonly use such symptoms as a self-handicapping strategy. Results supported these predictions for male subjects, but not for female subjects. Sex differences in the strategic use of shyness are discussed in relation to other research on sex differences in the etiology and correlates of social anxiety.

  18. The relationship between online video game involvement and gaming-related friendships among emotionally sensitive individuals.

    PubMed

    Kowert, Rachel; Domahidi, Emese; Quandt, Thorsten

    2014-07-01

    Some researchers believe that online gaming spaces can be socially accommodating environments for socially inhibited individuals, such as the socially inept, socially anxious, or shy. While previous research has examined, and found, significant links between these populations and online video game play, it remains unknown to what extent these spaces are contributing to tangible social benefits for the socially inhibited. The current study addresses this question by evaluating the link between gaming-related friendships and shyness, as quantified by emotional sensitivity. Drawing from a representative sample of German game players, the results indicate that emotionally sensitive players are using online gaming spaces differently from their less emotionally sensitive counterparts and reporting tangible differences in their in-game friendship networks. This suggests that online games hold the potential to be socially advantageous for shy individuals by allowing them to overcome their traditional social difficulties and generate new friendships as well as strengthen old ones.

  19. New taxa of Meconematini (Orthoptera: Tettigoniidae: Meconematinae) from Guangxi, China.

    PubMed

    Wang, Hanqiang; Liu, Xianwei; Li, Kai

    2015-04-02

    The following new taxa of Meconematini from Guangxi province were described: Sinothaumaspis damingshanicus Wang, Liu, Li gen. & sp. nov., Aphlugiolopsis punctipennis Wang, Liu, Li gen. & sp. nov., Eoxizicus (Eoxizicus) curvicercus Wang, Liu, Li sp. nov., Meconemopsis paraquadrinotata Wang, Liu, Li sp. nov., Neocrytopsis? unicolor Wang, Liu, Li sp. nov., Xiphidiopsis (Dinoxiphidiopsis) expressa Wang, Liu, Li sp. nov. Xiphidiopsis (Xiphidiopsis) fischerwaldheimi Gorochov, 1993, a synonym of Xiphidiopsis (Xiphidiopsis) jinxiuensis Xia & Liu, 1990 was described. The opposite gender of Sinocyrtaspis truncate Liu, 2000 and Abaxinicephora excellens Gorochov & Kang, 2005 were firstly described.  Xiphidiopsis (Dinoxiphidiopsis) jacobsoni Gorochov, 1993 was also firstly recorded from China. Two new combinations,  Meconemopsis quadrinotata (Bey-Bienko, 1971) Wang, Liu, Li comb. nov. and Xiphidiopsis (Dinoxiphidiopsis) fanjingshanensis (Shi & Du, 2006) Wang, Liu, Li comb. nov., as well as a synonym of the former Xizicus (Axizicus) xizangensis Jiao & Shi 2013 syn. nov. which respectively relate to M. paraquadrinotata sp. nov. and X. (D.) expressa sp. nov., were also noted.

  20. KSC01pd1884

    NASA Image and Video Library

    2001-12-19

    KENNEDY SPACE CENTER, FLA. - At SPACEHAB, Cape Canaveral, Fla., members of the STS-107 crew familiarize themselves with experiments and equipment for the mission. Pointing at a piece of equipment (center) is Mission Specialist Laurel Clark . At right is Mission Specialist Kalpana Chawla. STS-107 is a research mission. The primary payload is the first flight of the SHI Research Double Module (SHI/RDM). The experiments range from material sciences to life sciences (many rats). Also part of the payload is the Fast Reaction Experiments Enabling Science, Technology, Applications and Research (FREESTAR) that incorporates eight high priority secondary attached shuttle experiments: Mediterranean Israeli Dust Experiment (MEIDEX), Shuttle Ozone Limb Sounding Experiment (SOLSE-2), Student Tracked Atmospheric Research Satellite for Heuristic International Networking Experiment (STARSHINE), Critical Viscosity of Xenon-2 (CVX-2), Solar Constant Experiment-3 (SOLOCON-3), Prototype Synchrotron Radiation Detector (PSRD), Low Power Transceiver (LPT), and Collisions Into Dust Experiment -2 (COLLIDE-2). STS-107 is scheduled to launch in July 2002

  1. Relevance of the Rationalist-Intuitionist Debate for Ethics and Professionalism in Medical Education

    ERIC Educational Resources Information Center

    Leffel, G. Michael; Mueller, Ross A. Oakes; Curlin, Farr A.; Yoon, John D.

    2015-01-01

    Despite widespread pedagogical efforts to modify discrete behaviors in developing physicians, the professionalism movement has generally shied away from essential questions such as what virtues characterize the good physician, and how are those virtues formed? Although there is widespread adoption of medical ethics curricula, there is still no…

  2. Cold Shock Exoribonuclease R (VacB) is Involved in Aeromonas hydrophila Pathogenesis

    EPA Science Inventory

    In this study, we cloned and sequenced a virulence-associated gene (vacB) from a clinical isolate SSU of Aeromonas hydrophila. We identified this gene based on our recently annotated genome sequence of the environmental isolate ATCC 7966T of A. hydrophila and the vacB gene of Shi...

  3. Steer responses to feeding soybean hulls and steroid hormone implantation on toxic tall fescue pasture

    USDA-ARS?s Scientific Manuscript database

    Yearling steers were grazed on endophyte-infected ‘Kentucky-31’ tall fescue (Lolium arundinaceum) pastures for 77 days in 2007 and for 86 days in 2008 to evaluate effects of feeding pelleted soybean hulls (PSBH) and steroid hormone implants (SHI) on steer performance and physiology. Steers were str...

  4. Emphasizing the "Literacy" in "Scientific Literacy": A Concise Blueprint for Integrating Writing into Biology Classes

    ERIC Educational Resources Information Center

    Yule, Jeffrey V.; Wolf, William C.; Young, Nolan L.

    2010-01-01

    Effectively integrating writing into biology classes gives students the opportunity to develop a better understanding of and engagement with course content. Yet many instructors remain reluctant to emphasize writing. Some are concerned about the time commitment writing assessment requires. Others shy away from emphasizing writing in their classes…

  5. A business model for diagnostic startups-a business model for a new generation of diagnostics companies.

    PubMed

    Kurtzman, Gary

    2005-10-01

    Venture capital has tended to shy away from diagnostics companies, whose products are not predicated on the blockbuster model of pharmaceuticals. But several new diagnostics companies are developing products that hold immense potential to improve healthcare delivery. Here's why venture investors should take another look at the diagnostics area.

  6. 75 FR 79024 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-ODVA, Inc.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-17

    ... Precision Co., Ltd., Seoul, Republic of Korea; Monaghan Engineering, Inc., Dripping Springs, TX; Samsung..., Shihung-Shi, Republic of Korea, have been added as parties to this venture. Also, Schweitzer Engineering.... Brink, Director of Civil Enforcement, Antitrust Division. [FR Doc. 2010-31593 Filed 12-16-10; 8:45 am...

  7. Cold Shock Exoribonuclease R(VacB) is involved in Aeromonas hydrophila Virulence

    EPA Science Inventory

    In this study, we cloned and sequenced a virulence-associated gene (vacB) from a clinical isolate SSU of Aeromonas hydrophila. We identified this gene based on our recently annotated genome sequence of the environmental isolate ATCC 7966T of A. hydrophila and the vacB gene of Shi...

  8. A NOVEL S-ADENOSYL-L-METHIONINE: ARSENIC (III) METHYLTRANSFERASE FROM RAT LIVER CYTOSOL

    EPA Science Inventory

    A Novel S-Adenosyl-L-methionine: Arsenic(III) Methyltransferase from Rat Liver Cytosol
    Shan Lin, Qing Shi, F. Brent Nix, Miroslav Styblo, Melinda A. Beck, Karen M. Herbin-Davis, Larry L. Hall, Josef B. Simeonsson, and David J. Thomas
    S-adenosyl-L-methionine (AdoMet): ar...

  9. Traffic Analysis for Network Security using Learning Theory and Streaming Algorithms

    DTIC Science & Technology

    2008-09-01

    to have had friends who have immensely improved my research and presentation – David Brumley, Hubert Chan, Elena Nabieva, Vyas Sekar, and Runting Shi...Information Assurance and Security 2001, 2001. [15] Marco Barreno, Blaine Nelson, Russell Sears, Anthony D. Joseph, and J. D. Tygar. Can machine learning be

  10. The Emotionally Sensitive Adolescent.

    ERIC Educational Resources Information Center

    Shaughnessy, Michael F.; Lehtonen, Kimmo

    This paper provides a list of signs, symptoms, and indicators of emotionally sensitive adolescents includes clinging behavior, withdrawn behavior, shy/inhibited behavior, represses anger, poor reaction to criticism, makes self-disparaging statements, low self-esteem, "can't forgive self or others," ruined by a small critical comment, exploding…

  11. Communication Incompetencies: A Theory of Training Oral Performance Behavior.

    ERIC Educational Resources Information Center

    Phillips, Gerald M.

    Arguing that the most effective method to help shy people develop essential social and communication skills is a modification of the way these people perform, this book proposes a system which includes skills training, cognitive restructuring, and systematic relaxation. The book's 12 chapters are as follows: (1) Understanding Communication…

  12. Cost-effectiveness analysis of a vaccination program for the prevention of herpes zoster and post-herpetic neuralgia in adults aged 50 and over in Germany.

    PubMed

    Préaud, Emmanuelle; Uhart, Mathieu; Böhm, Katharina; Aidelsburger, Pamela; Anger, Delphine; Bianic, Florence; Largeron, Nathalie

    2015-01-01

    Herpes zoster (HZ; shingles) is a common viral disease that affects the nerves and surrounding skin causing a painful dermatomal rash and leading to debilitating complications such as, mainly, post-herpetic neuralgia (PHN). Currently, there is no effective treatment for HZ and PHN. The objective of this study was to assess the cost-effectiveness of a HZ vaccination program in Germany. An existing Markov Model was adapted to the German healthcare setting to compare a vaccination policy to no vaccination on a lifetime time-horizon, considering 2 scenarios: vaccinating people starting at the age of 50 or at the age of 60 years, from the perspective of the statutory health insurance (SHI) and the societal perspective. According to the perspective, vaccinating 20% of the 60+ German population resulted in 162,713 to 186,732 HZ and 31,657 to 35,793 PHN cases avoided. Corresponding incremental cost-effectiveness ratios (ICER) were 39,306 €/QALY from the SHI perspective and 37,417 €/QALY from a societal perspective. Results for the 50+ German population ranged from 336,468 to 394,575 HZ and from 48,637 to 56,087 PHN cases avoided from the societal perspective. Corresponding ICER were 39,782 €/QALY from a SHI perspective and 32,848 €/QALY from a societal perspective. Sensitivity analyses showed that results are mainly impacted by discount rates, utility values and use of alternative epidemiological data.The model indicated that a HZ vaccination policy in Germany leads to significant public health benefits and could be a cost-effective intervention. The results were robust and consistent with local and international existing literature.

  13. Parametric imaging using subharmonic signals from ultrasound contrast agents in patients with breast lesions.

    PubMed

    Eisenbrey, John R; Dave, Jaydev K; Merton, Daniel A; Palazzo, Juan P; Hall, Anne L; Forsberg, Flemming

    2011-01-01

    Parametric maps showing perfusion of contrast media can be useful tools for characterizing lesions in breast tissue. In this study we show the feasibility of parametric subharmonic imaging (SHI), which allows imaging of a vascular marker (the ultrasound contrast agent) while providing near complete tissue suppression. Digital SHI clips of 16 breast lesions from 14 women were acquired. Patients were scanned using a modified LOGIQ 9 scanner (GE Healthcare, Waukesha, WI) transmitting/receiving at 4.4/2.2 MHz. Using motion-compensated cumulative maximum intensity (CMI) sequences, parametric maps were generated for each lesion showing the time to peak (TTP), estimated perfusion (EP), and area under the time-intensity curve (AUC). Findings were grouped and compared according to biopsy results as benign lesions (n = 12, including 5 fibroadenomas and 3 cysts) and carcinomas (n = 4). For each lesion CMI, TTP, EP, and AUC parametric images were generated. No significant variations were detected with CMI (P = .80), TTP (P = .35), or AUC (P = .65). A statistically significant variation was detected for the average pixel EP (P = .002). Especially, differences were seen between carcinoma and benign lesions (mean ± SD, 0.10 ± 0.03 versus 0.05 ± 0.02 intensity units [IU]/s; P = .0014) and between carcinoma and fibroadenoma (0.10 ± 0.03 versus 0.04 ± 0.01 IU/s; P = .0044), whereas differences between carcinomas and cysts were found to be nonsignificant. In conclusion, a parametric imaging method for characterization of breast lesions using the high contrast to tissue signal provided by SHI has been developed. While the preliminary sample size was limited, results show potential for breast lesion characterization based on perfusion flow parameters.

  14. Assessing the exchange coupling in binuclear lanthanide(iii) complexes and the slow relaxation of the magnetization in the antiferromagnetically coupled Dy2 derivative.

    PubMed

    Chow, Chun Y; Bolvin, Hélène; Campbell, Victoria E; Guillot, Régis; Kampf, Jeff W; Wernsdorfer, Wolfgang; Gendron, Frédéric; Autschbach, Jochen; Pecoraro, Vincent L; Mallah, Talal

    2015-07-01

    We report here the synthesis and the investigation of the magnetic properties of a series of binuclear lanthanide complexes belonging to the metallacrown family. The isostructural complexes have a core structure with the general formula [Ga 4 Ln 2 (shi 3- ) 4 (Hshi 2- ) 2 (H 2 shi - ) 2 (C 5 H 5 N) 4 (CH 3 OH) x (H 2 O) x ]· x C 5 H 5 N· x CH 3 OH· x H 2 O (where H 3 shi = salicylhydroxamic acid and Ln = Gd III 1 ; Tb III 2 ; Dy III 3 ; Er III 4 ; Y III 5 ; Y III 0.9 Dy III 0.1 6 ). Apart from the Er-containing complex, all complexes exhibit an antiferromagnetic exchange coupling leading to a diamagnetic ground state. Magnetic studies, below 2 K, on a single crystal of 3 using a micro-squid array reveal an opening of the magnetic hysteresis cycle at zero field. The dynamic susceptibility studies of 3 and of the diluted DyY 6 complexes reveal the presence of two relaxation processes for 3 that are due to the excited ferromagnetic state and to the uncoupled Dy III ions. The antiferromagnetic coupling in 3 was shown to be mainly due to an exchange mechanism, which accounts for about 2/3 of the energy gap between the antiferro- and the ferromagnetic states. The overlap integrals between the Natural Spin Orbitals (NSOs) of the mononuclear fragments, which are related to the magnitude of the antiferromagnetic exchange, are one order of magnitude larger for the Dy 2 than for the Er 2 complex.

  15. Is prevention of atopic eczema with hydrolyzed formulas cost-effective? A health economic evaluation from Germany.

    PubMed

    Mertens, Janina; Stock, Stephanie; Lüngen, Markus; von Berg, Andrea; Krämer, Ursula; Filipiak-Pittroff, Birgit; Heinrich, Joachim; Koletzko, Sibylle; Grübl, Armin; Wichmann, H-Erich; Bauer, Carl-P; Reinhardt, Dietrich; Berdel, Dietrich; Gerber, Andreas

    2012-09-01

    The German Infant Nutritional Intervention (GINI) trial, a prospective, randomized, double-blind intervention, enrolled children with a hereditary risk for atopy. When fed with certain hydrolyzed formulas for the first 4 months of life, the risk was reduced by 26-45% in PP and 8-29% in intention-to-treat (ITT) analyses compared with children fed with regular cow's milk at age 6. The objective was to assess the cost-effectiveness of feeding hydrolyzed formulas. Cost-effectiveness was assessed with a decision tree model programmed in TreeAge. Costs and effects over a 6-yr period were analyzed from the perspective of the German statutory health insurance (SHI) and a societal perspective at a 3% effective discount rate followed by sensitivity analyses. The extensively hydrolyzed casein formula would be the most cost-saving strategy with savings of 478 € per child treated in the ITT analysis (CI95%: 12 €; 852 €) and 979 € in the PP analysis (95%CI: 355 €; 1455 €) from a societal perspective. If prevented cases are considered, the partially whey hydrolyzed formula is cost-saving (ITT -5404 €, PP -6358 €). From an SHI perspective, the partially whey hydrolyzed formula is cost-effective, but may also be cost-saving depending on the scenario. An extensively hydrolyzed whey formula also included into the analysis was dominated in all analyses. For the prevention of AE, two formulas can be cost-effective or even cost-saving. We recommend that SHI should reimburse formula feeding or at least the difference between costs for cow's milk formula and the most cost-effective formula. © 2012 John Wiley & Sons A/S.

  16. Comparative Analysis of Latex Transcriptome Reveals Putative Molecular Mechanisms Underlying Super Productivity of Hevea brasiliensis

    PubMed Central

    Li, Heping; Fan, Yujie; Yang, Jianghua; Qi, Jiyan; Li, Huibo

    2013-01-01

    Increasing demand for natural rubber prompts studies into the mechanisms governing the productivity of rubber tree ( Hevea brasiliensis ). It is very interesting to notice that a rubber tree of clone PR107 in Yunnan, China is reported to yield more than 20 times higher than the average rubber tree. This super-high-yielding (SHY) rubber tree (designated as SY107), produced 4.12 kg of latex (cytoplasm of rubber producing laticifers, containing about 30% of rubber) per tapping, more than 7-fold higher than that of the control. This rubber tree is therefore a good material to study how the rubber production is regulated at a molecular aspect. A comprehensive cDNA-AFLP transcript profiling was performed on the latex of SY107 and its average counterparts by using the 384 selective primer pairs for two restriction enzyme combinations (ApoI/MseI and TaqI/MseI). A total of 746 differentially expressed (DE) transcript-derived fragments (TDFs) were identified, of which the expression patterns of 453 TDFs were further confirmed by RT-PCR. These RT-PCR confirmed TDFs represented 352 non-redundant genes, of which 215 had known or partially known functions and were grouped into 10 functional categories. The top three largest categories were transcription and protein synthesis (representing 24.7% of the total genes), defense and stress (15.3%), and primary and secondary metabolism (14.0%). Detailed analysis of the DE-genes suggests notable characteristics of SHY phenotype in improved sucrose loading capability, rubber biosynthesis-preferred sugar utilization, enhanced general metabolism and timely stress alleviation. However, the SHY phenotype has little correlation with rubber-biosynthesis pathway genes. PMID:24066172

  17. Functional analysis of fruitless gene expression by transgenic manipulations of Drosophila courtship

    PubMed Central

    Villella, Adriana; Ferri, Sarah L.; Krystal, Jonathan D.; Hall, Jeffrey C.

    2005-01-01

    A gal4-containing enhancer–trap called C309 was previously shown to cause subnormal courtship of Drosophila males toward females and courtship among males when driving a conditional disrupter of synaptic transmission (shiTS). We extended these manipulations to analyze all features of male-specific behavior, including courtship song, which was almost eliminated by driving shiTS at high temperature. In the context of singing defects and homosexual courtship affected by mutations in the fru gene, a tra-regulated component of the sex-determination hierarchy, we found a C309/traF combination also to induce high levels of courtship between pairs of males and “chaining” behavior in groups; however, these doubly transgenic males sang normally. Because production of male-specific FRUM protein is regulated by TRA, we hypothesized that a fru-derived transgene encoding the male (M) form of an Inhibitory RNA (fruMIR) would mimic the effects of traF; but C309/fruMIR males exhibited no courtship chaining, although they courted other males in single-pair tests. Double-labeling of neurons in which GFP was driven by C309 revealed that 10 of the 20 CNS clusters containing FRUM in wild-type males included coexpressing neurons. Histological analysis of the developing CNS could not rationalize the absence of traF or fruMIR effects on courtship song, because we found C309 to be coexpressed with FRUM within the same 10 neuronal clusters in pupae. Thus, we hypothesize that elimination of singing behavior by the C309/shiTS combination involves neurons acting downstream of FRUM cells PMID:16179386

  18. The "Tyranny of Choice": Choice Overload as a Possible Instance of Effort Discounting

    ERIC Educational Resources Information Center

    Reed, Derek D.; Reed, Florence D. DiGennaro; Chok, James; Brozyna, Gary A.

    2011-01-01

    When making a choice, people like to have options, but an emerging literature on "choice overload" suggests that the provision of too many options results in adverse experiences, including a depletion of cognitive resources and postdecision feelings of regret. A strong implication is that individuals should shy away from situations…

  19. Use of Hypnotherapy for Assertive Training and Behavioral Rehearsal: An Active Mode of Therapy.

    ERIC Educational Resources Information Center

    DeVoge, Susan D.

    This paper describes a treatment approach which uses hypnotherapy techniques in combination with assertive training and behavioral rehearsal. It discusses the use of this treatment with a client who exhibited psychogenic symptoms due to personal anxiety. At the beginning of the treatment the client was shy, non-assertive and extremely…

  20. Doing What Your Big Sister Does: Sex, Postfeminism and the YA Chick Lit Series

    ERIC Educational Resources Information Center

    Bullen, Elizabeth; Toffoletti, Kim; Parsons, Liz

    2011-01-01

    Mass-marketed teen chick lit has become a publishing phenomenon and has begun to attract critical interest among children's literature scholars. Much of this critical work, however, has shied away from robust critical assessment of the postfeminist conditions informing the production and reception of young adult series like Private, Gossip Girl…

  1. Cognitive Biases and the Link between Shyness and Social Anxiety in Early Adolescence

    ERIC Educational Resources Information Center

    Weeks, Murray; Ooi, Laura L.; Coplan, Robert J.

    2016-01-01

    Shy children display wariness in unfamiliar social situations and often experience feelings of social anxiety. This study explored the potential mediating role of cognitive biases in the link between shyness and social anxiety in early adolescence. In particular, we focused on judgments of the probability and cost of negative social situations…

  2. "It's Not Rocket Science!": High School Sociology Teachers' Conceptions of Sociology

    ERIC Educational Resources Information Center

    DeCesare, Michael

    2006-01-01

    Since academic sociology's birth in this country, sociologists have not been shy about publicly praising and ridiculing the discipline. Though sociologists have been the primary participants in the seemingly endless debates about sociology's proper subject matter, methods, and purpose, there is another group that has also struggled over the past…

  3. Identifying the Pains and Problems of Shyness: A Content Analysis.

    ERIC Educational Resources Information Center

    Carducci, Bernardo J.; Ragains, Kristen D.; Kee, Kathy L.; Johnson, Michael R.; Duncan, Heather R.

    Contemporary literature on shyness has made steady progression over the last 20 years in theoretical, methodological, and clinical sophistication; however, little research has investigated how shyness is experienced by shy individuals. The purpose of the present study was to gain a more in-depth understanding of shyness as experienced by shy…

  4. Using a Hybrid Approach for a Leadership Cohort Program

    ERIC Educational Resources Information Center

    Norman, Maxine A.

    2013-01-01

    Because information technology continues to change rapidly, Extension is challenged with learning and using technology appropriately. We assert Extension cannot shy away from the challenges but must embrace technology because audiences and external forces demand it. A hybrid, or blended, format of a leadership cohort program was offered to public…

  5. Psychological Profile of the Female Adolescent Incest Victim.

    ERIC Educational Resources Information Center

    German, Don-Nee E.; And Others

    1990-01-01

    Forty female incest victims, ages 12-18, were administered personality and self-concept assessments. Subjects were found to be shy, expedient, guilt-prone, aggressive, realistic, and withdrawn and to have low overall self-concept. Subjects showed more confidence about physical appearance and intellectual and school status than other aspects of…

  6. Implementation of CDC's School Health Index in 3 Midwest Middle Schools: Motivation for Change

    ERIC Educational Resources Information Center

    Sherwood-Puzzello, Catherine M.; Miller, Michelle; Lohrmann, David; Gregory, Patricia

    2007-01-01

    Background: The Centers for Disease Control and Prevention's School Health Index (SHI), a guide for completing a coordinated school-based program needs assessment relative to healthy eating, physical activity, a tobacco-free lifestyle, and prevention of other health risk behaviors and conditions, was used to assess current programming at 3…

  7. Never Too Early to Learn: Antibias Education for Young Children

    ERIC Educational Resources Information Center

    Hooven, Jennifer; Runkle, Katherine; Strouse, Laurie; Woods, Misty; Frankenberg, Erica

    2018-01-01

    Four early childhood educators, along with a university researcher, describe their efforts to implement an antiracist, antibias curriculum in a daycare and preschool setting. Even very young children can learn important lessons about race, diversity, and equity, they argue, and teachers should not shy away from addressing these issues at staff…

  8. "I Want to Play Alone": Assessment and Correlates of Self-Reported Preference for Solitary Play in Young Children

    ERIC Educational Resources Information Center

    Coplan, Robert J.; Ooi, Laura L.; Rose-Krasnor, Linda; Nocita, Gabriella

    2014-01-01

    The goal of this study was to develop and validate an interview assessment of "preference for solitary activities" for use with young children. We also tested the postulation that negative peer experiences would heighten preference for solitude, particularly among young shy children. Participants were N?=?193 children (87 boys, 106…

  9. Alone Is a Crowd: Social Motivations, Social Withdrawal, and Socioemotional Functioning in Later Childhood

    ERIC Educational Resources Information Center

    Coplan, Robert J.; Rose-Krasnor, Linda; Weeks, Murray; Kingsbury, Adam; Kingsbury, Mila; Bullock, Amanda

    2013-01-01

    The primary goals of this study were to test a conceptual model linking social approach and avoidance motivations, socially withdrawn behaviors, and peer difficulties in later childhood and to compare the socioemotional functioning of different subtypes of withdrawn children (shy, unsociable, avoidant). Participants were 367 children, aged 9-12…

  10. Risk factors for anti-MRSA drug resistance.

    PubMed

    Abe, Yasuhisa; Shigemura, Katsumi; Yoshida, Hiroyuki; Fujisawa, Masato; Arakawa, Soichi

    2012-11-01

    Meticillin-resistant Staphylococcus aureus (MRSA)-related infections have recently been spreading and are difficult to control, partly because affected patients are frequently in a poor condition. This study retrospectively investigated recent MRSA-related infections focusing on the relationship between clinical risk factors and anti-MRSA drug resistance. The patients with MRSA-related infections in Kobe University Hospital (Kobe, Japan) in 2009 were enrolled in the study. The relationships between various clinical risk factors as well as MRSA bacterial DNA concentration with minimum inhibitory concentrations (MICs) of anti-MRSA drugs were examined. In total, 44 patients were enrolled in the study and MRSA was isolated from blood (23 patients), urine (12 patients) and nasal secretions (9 patients). There was only one resistant strain to linezolid (LZD) among the anti-MRSA drugs tested, and this strain was considered staphylococcal cassette chromosome mec (SCCmec) type IIa from phage open-reading frame typing analyses. Statistical analyses showed that MRSA bacterial DNA concentration, cancer and use of a respirator, respectively, had a significant relationship with the MICs of LZD (P=0.0058) and arbekacin (ABK) (P=0.0003), of quinupristin/dalfopristin (Q/D) (P=0.0500) and ABK (P=0.0133), and of Q/D (P=0.0198) and vancomycin (P=0.0036). In conclusion, bacterial DNA concentration, cancer and use of a respirator were found to be significant risk factors for lower susceptibilities to anti-MRSA drugs; one strain was resistant to LZD. We suggest that further investigation and surveillance for MRSA-related infection are necessary for preventing the spread of MRSA-related infections. Copyright © 2012 Elsevier B.V. and the International Society of Chemotherapy. All rights reserved.

  11. Analysis of the tsunami generated by the MW 7.8 1906 San Francisco earthquake

    USGS Publications Warehouse

    Geist, E.L.; Zoback, M.L.

    1999-01-01

    We examine possible sources of a small tsunami produced by the 1906 San Francisco earthquake, recorded at a single tide gauge station situated at the opening to San Francisco Bay. Coseismic vertical displacement fields were calculated using elastic dislocation theory for geodetically constrained horizontal slip along a variety of offshore fault geometries. Propagation of the ensuing tsunami was calculated using a shallow-water hydrodynamic model that takes into account the effects of bottom friction. The observed amplitude and negative pulse of the first arrival are shown to be inconsistent with small vertical displacements (~4-6 cm) arising from pure horizontal slip along a continuous right bend in the San Andreas fault offshore. The primary source region of the tsunami was most likely a recently recognized 3 km right step in the San Andreas fault that is also the probable epicentral region for the 1906 earthquake. Tsunami models that include the 3 km right step with pure horizontal slip match the arrival time of the tsunami, but underestimate the amplitude of the negative first-arrival pulse. Both the amplitude and time of the first arrival are adequately matched by using a rupture geometry similar to that defined for the 1995 MW (moment magnitude) 6.9 Kobe earthquake: i.e., fault segments dipping toward each other within the stepover region (83??dip, intersecting at 10 km depth) and a small component of slip in the dip direction (rake=-172??). Analysis of the tsunami provides confirming evidence that the 1906 San Francisco earthquake initiated at a right step in a right-lateral fault and propagated bilaterally, suggesting a rupture initiation mechanism similar to that for the 1995 Kobe earthquake.

  12. Design of prospective study of acute coronary syndrome hospitalization after smoking ban in public places in Hyogo prefecture: comparison with Gifu, a prefecture without a public smoking ban.

    PubMed

    Sato, Yukihito; Minatoguchi, Shinya; Nishigaki, Kazuhiko; Hirata, Ken-ichi; Masuyama, Tohru; Furukawa, Yutaka; Uematsu, Masaaki; Yoshikawa, Junichi; Otsuji, Satoru; Iida, Mami; Fujiwara, Hisayoshi

    2014-02-01

    Hyogo is the second prefecture, after Kanagawa, to enact a smoking ban in public places in Japan. The effect of this smoking ban on acute coronary syndrome (ACS) has not been evaluated. Changes in the annual number of ACS hospital cases in Hyogo Prefecture, before and after the enactment of the prefectural legislative ban on smoking in public places, are to be compared with those in Gifu Prefecture, where there is no smoking-ban legislation. Consecutive Hyogo residents with ACS, admitted to 33 major hospitals in the Hanshin-Awaji-Kobe district, which covers 56% of the population, during the 12 months before implementation of the legislation (April 2012 through March 2013) and during the same 24 months thereafter (April 2013 through March 2015) will be enrolled. Consecutive patients with ACS, who are Gifu residents, treated at the 20 major hospitals in Gifu Prefecture will be enrolled as geographical controls. The primary endpoint is the change in number of ACS admissions from April 2012 through March 2015, considering the periods before and after the smoking-ban legislation in Hyogo prefecture. Our study has certain strengths: (1) This is the first large Japanese study of ACS registry with smoking-ban legislation. (2) Major hospitals in the Hanshin-Awaji-Kobe district are included. (3) The data will cover 3 years including 1 year before legislation enactment. (4) The data will be compared with those of Gifu Prefecture, where smoking-ban legislation will not be enacted. (5) The very large database makes possible analysis of subgroups based on age and gender. Copyright © 2013 Japanese College of Cardiology. Published by Elsevier Ltd. All rights reserved.

  13. Dynamic stress changes during earthquake rupture

    USGS Publications Warehouse

    Day, S.M.; Yu, G.; Wald, D.J.

    1998-01-01

    We assess two competing dynamic interpretations that have been proposed for the short slip durations characteristic of kinematic earthquake models derived by inversion of earthquake waveform and geodetic data. The first interpretation would require a fault constitutive relationship in which rapid dynamic restrengthening of the fault surface occurs after passage of the rupture front, a hypothesized mechanical behavior that has been referred to as "self-healing." The second interpretation would require sufficient spatial heterogeneity of stress drop to permit rapid equilibration of elastic stresses with the residual dynamic friction level, a condition we refer to as "geometrical constraint." These interpretations imply contrasting predictions for the time dependence of the fault-plane shear stresses. We compare these predictions with dynamic shear stress changes for the 1992 Landers (M 7.3), 1994 Northridge (M 6.7), and 1995 Kobe (M 6.9) earthquakes. Stress changes are computed from kinematic slip models of these earthquakes, using a finite-difference method. For each event, static stress drop is highly variable spatially, with high stress-drop patches embedded in a background of low, and largely negative, stress drop. The time histories of stress change show predominantly monotonic stress change after passage of the rupture front, settling to a residual level, without significant evidence for dynamic restrengthening. The stress change at the rupture front is usually gradual rather than abrupt, probably reflecting the limited resolution inherent in the underlying kinematic inversions. On the basis of this analysis, as well as recent similar results obtained independently for the Kobe and Morgan Hill earthquakes, we conclude that, at the present time, the self-healing hypothesis is unnecessary to explain earthquake kinematics.

  14. Development of the KOSMS management simulation training system and its application

    NASA Astrophysics Data System (ADS)

    Takatsu, Yoshiki

    The use of games which simulate actual corporate management has recently become more common and is now utilized in various ways for in-house corporate training courses. KOSMS (Kobe Steel Management Simulation System), a training system designed to help improve the management skills of senior management staff, is a unique management simulation training system in which the participants, using personal computers, must make decisions concerning a variety of management activities, in simulated competition with other corporations. This report outlines the KOSMS system, and describes the basic structure and detailed contents of the management simulation models, and actual application of the KOSMS management simulation training.

  15. Issues in intelligent robots for search and rescue

    NASA Astrophysics Data System (ADS)

    Casper, Jennifer L.; Micire, Mark; Murphy, Robin R.

    2000-07-01

    Since the 1995 Oklahoma City bombing and Kobe, Japan, earthquake, robotics researchers have been considering search and rescue as a humanitarian research domain. The recent devastation in Turkey and Taiwan, compounded with the new Robocup Rescue and AAAI Urban Search and Rescue robot competition, may encourage more research. However, roboticists generally go not have access to domain experts: the emergency workers or first providers. This paper shares our understanding of urban search and rescue, based on our active research in this area and training sessions with rescue workers from the Hillsborough County (Florida) Fire Departments. The paper is intended to be a stepping stone for roboticists entering the field.

  16. Concluding remarks to ICAME2011

    NASA Astrophysics Data System (ADS)

    Campbell, S. J.

    2012-03-01

    An overview of the main aspects of ICAME2011 - tutorial lectures, oral and poster presentations, evening sessions - is presented along with a brief outline of several of the scientific highlights. Among other topics considered are the involvements of young scientists and female scientists, and operation of the oral and poster sessions. Despite the most challenging combinations of circumstances in the lead up to ICAME2011 that resulted in the change of venue at an advanced stage from Tokyo to Kobe, the Committee organised a high quality conference with many positive outcomes for the future. The Mössbauer community acknowledges and appreciates these efforts greatly.

  17. "When Words Don't Come Easily": Personal Narratives from Adolescents Experiencing Shyness as an Emotional and Behavioural Problem in the School Context

    ERIC Educational Resources Information Center

    Lund, Ingrid

    2016-01-01

    The purpose of this article is to present narratives from 15 adolescents experiencing shy behaviour as an emotional and behavioural problem in the school context in light of narrative understanding. The investigation is intended to generate knowledge about this largely under-researched phenomenon based on the personal accounts of those who are…

  18. Developing a Teacher Administered Anxiety Rating Scale Suitable for Five to Seven-Year-Old Children

    ERIC Educational Resources Information Center

    Goulet, Joseph

    2013-01-01

    This paper presents results of twin studies pertinent to the development of a rating scale designed for use by teachers to identify anxious and shy children, aged 5 to 7 years, in Kindergarten and Grade One. Currently, no instruments designed specifically for this purpose exist. Children experiencing difficulty with internalizing disorders such as…

  19. Electrically Mediated Trauma Repair

    DTIC Science & Technology

    1994-07-07

    potential (TEP) (Johnston and Hoshiko, 1971; Rick et al., 1988; Shi and Borgens, 1994). In the axolotl neurulae, a gradient of 10 - 20 mV/mm is...reach 60-80 mV/mm. A more shallow voltage gradient is observed in the transverse plane of axolotl neurulae associated with mirror image outwardly

  20. The Scientific Instruments of Charles Wheatstone and the Blending of Science, Art, and Culture

    ERIC Educational Resources Information Center

    Metz, Don

    2015-01-01

    Charles Wheatstone was a British scientist who is most often remembered for his association with the Wheatstone bridge for measuring electrical resistance. A painfully shy man in public, Wheatstone, in reality, possessed a vibrant personality and a wide array of personal interests from acoustics to electricity to optics and parlour tricks. In this…

  1. Sport Psychology Teaching Approaches for High School Coaches and Their Student-Athletes

    ERIC Educational Resources Information Center

    Gilbert, Jenelle N.

    2017-01-01

    Coaches lacking a formal background in sport psychology may shy away from teaching these skills in favor of teaching physical skills with which they are more familiar. Other coaches may assume that athletes will learn sport psychology skills as a byproduct of their coaching pedagogy. Regardless, high school coaches are responsible for teaching…

  2. Videodisks Offer a Detailed Portrait of Qin, the First Chinese Emperor.

    ERIC Educational Resources Information Center

    Watkins, Beverly T.

    1992-01-01

    Project Emperor-I has issued two interactive videodiscs on China's first emperor, Qin Shi Huang Di. The videodiscs contain film footage from the archaeological excavation in China, images of artifacts, interviews with Qin specialists, and the full text of articles about the ancient burial site. Development of the videodiscs for scholars involved…

  3. Large Three-Dimensional Photonic Crystals Based on Monocrystalline Liquid Crystal Blue Phases (Postprint)

    DTIC Science & Technology

    2017-09-28

    5192 (2011). 39. Shi, Y., Mo, J., Wei, J. & Guo, J. Chiral assembly and plasmonic response of silver nanoparticles in a three-dimensional blue-phase... synthesis of a silicon photonic crystal with a complete three-dimensional bandgap near 1.5 µm. Nature 405, 437–440 (2000). 3. Arsenault, A. et al

  4. A Business Model for Diagnostic Startups-A Business Model for a New Generation Of Diagnostics Companies

    PubMed Central

    Kurtzman, Gary

    2005-01-01

    Venture capital has tended to shy away from diagnostics companies, whose products are not predicated on the blockbuster model of pharmaceuticals. But several new diagnostics companies are developing products that hold immense potential to improve healthcare delivery. Here’s why venture investors should take another look at the diagnostics area. PMID:23424311

  5. Gifted Education in the Hong Kong Special Administrative Region

    ERIC Educational Resources Information Center

    Tommis, Stephen

    2013-01-01

    Despite its close geographical, economic, and political ties with mainland China, Hong Kong has not followed the same trajectory on gifted education but instead has preferred to adopt a more Western approach to the definitions and provision for gifted learners (Shi & Zixiu, 2000; Zou, Yang, & Greene, 2007). Hong Kong is, on most measures…

  6. Regrouping Students

    ERIC Educational Resources Information Center

    DelViscio, James L.; Muffs, Michael L.

    2007-01-01

    Good teachers were shying away from accepting 4th-grade positions because of the growing accountability pressures that were being unfairly brought to bear on that grade level. Highly publicized reports of the state's new battery of standardized assessments were scaring off applicants. To address the personnel needs while more fairly sharing the…

  7. Chinese International Students' Advice to Incoming First-Year Students: Involving Students in Conversations "with" Them, Not about Them

    ERIC Educational Resources Information Center

    Heng, Tang T.

    2018-01-01

    This study examined advice Chinese internationals would give to incoming Chinese international first-year students to ease their US college transitions. While the study was limited to 18 students from private, well ranked, 4-year liberal arts colleges who all appeared to be coping with their transitions (struggling students may have shied from…

  8. Evansville: A Proactive Approach to Improvement. The Story behind the Indiana State Board of Education's Recent Decision

    ERIC Educational Resources Information Center

    Anderson, Charis

    2014-01-01

    The Indiana State Board of Education (ISBE) has not been shy about exercising its authority to intervene in chronically underperforming schools. Under the state's Public Law 221, the Indiana Board can mandate specific interventions for any school that has received six consecutive failing grades under the state's accountability system--up to a…

  9. Development of an Operational Multi-sensor and Multi-channel Aerosol Assimilation Package Using NAAPS and NAVDAS

    DTIC Science & Technology

    2010-09-30

    5593-1, 2010, EGU General Assembly 2010. Shi, Y., J. Zhang, J. S. Reid, E. Hyer, Evaluation of MISR Aerosol Optical Depth Product for Aerosol Data...a surrogate for aerosol type, as large η values are generally related to fine mode aerosols, such as sulfate and smoke aerosols, and small η values

  10. Chemistry: Coping with Change...Creatively.

    ERIC Educational Resources Information Center

    Barron, Marcelline A.

    Developed for mathematics-shy high school chemistry students, this laboratory manual is suitable for use with any chemistry textbook. Seventy-three experiments, based on a theme of change, are grouped into 5 general areas: (1) 9 experiments focusing on skills needed in observing reality; (2) 19 experiments interpreting how reality changes,…

  11. Stopping Sexual Assault on Private College Campuses: Impact Evaluation of a Prevention and Awareness Intervention Conducted with Community Partners at a Christian University

    ERIC Educational Resources Information Center

    Johnson, Alycia; Butcher, Melissa; Thomas, Kate H.; Jemsek, Jacqueline; Shields, Margaret M.

    2016-01-01

    Purpose: Prevention advocates work hard to create and deliver sexual assault awareness programs on college campuses, including Christian universities. To do so requires savvy planning and a high degree of cultural competence, as a review of the literature indicates that some Christian campuses shy away from the topic and refuse to allow needed…

  12. Music in the Life Skills Classroom

    ERIC Educational Resources Information Center

    van Vuuren, Eurika Jansen; van Niekerka, Caroline

    2015-01-01

    Generalist educators in South Africa shy away from music in the subjects Life Skills (Dance, Drama, Music, Visual Art, Physical Education and Personal and Social Well-being) and Creative Arts (Dance, Drama, Music, Visual Art) and universities are not delivering generalist students for the subject demands. In-service educators, as well as subject…

  13. Securing Emergency State Data in a Tactical Computing Environment

    DTIC Science & Technology

    2010-12-01

    in a Controlled Manner, 19th IEEE Symposium on Computer-Based Medical Systems (CBMS󈧊), 847–854. [38] K. Kifayat, D. Llewellyn - Jones , A. Arabo, O...Drew, M. Merabti, Q. Shi, A. Waller, R. Craddock, G. Jones , State-of-the-Art in System-of-Systems Security for Crisis Management, Fourth Annual

  14. Multicultural Content and Class Participation: Do Students Self-Censor?

    ERIC Educational Resources Information Center

    Hyde, Cheryl A.; Ruth, Betty J.

    2002-01-01

    Through survey and focus group data, examined student discomfort in social work courses, reasons for self-censorship, and solutions to self-censorship. Found that general classroom factors (being too shy or being unprepared), not political correctness, were more likely to be reasons for self-censorship. Solutions focused on the faculty's role in…

  15. Do Shy Kids Have a Chance of Getting to College?

    ERIC Educational Resources Information Center

    Hanley, Thomas A., Jr.

    2005-01-01

    In this article, the author discusses the importance of teacher recommendations for students who exhibit extreme shyness during college interviews. Admission committees at some colleges are apparently questioning the propensity to favor students who evidence leadership, and who are naturally outgoing, in seeking to balance and diversify the…

  16. Once hurt, twice shy: Social pain contributes to social anxiety.

    PubMed

    Fung, Klint; Alden, Lynn E

    2017-03-01

    Social rejection has been consistently linked to the development of social anxiety. However, mechanisms underlying the relation have been largely unexplored, which presents an obstacle to fully understanding the origins of social anxiety and to the development of effective prevention and treatment strategies. Two studies were conducted to test the hypothesis that the emotion of social pain following rejection promotes the development of social anxiety in subsequent situations. In Study 1, undergraduate participants were exposed to 2 social situations (Cyberball) 2 days apart. Participants who were rejected in the first situation reported higher social anxiety before and during the second situation relative to those who were included. This effect was fully mediated by initial social pain intensity. In Study 2, all participants were initially rejected. Using double-blinded drug administration, participants were randomly assigned to ingest acetaminophen to alleviate the social pain from rejection, or a sugar placebo. As predicted, the acetaminophen group reported lower social anxiety before and during the second situation. Approximately half of the effect was mediated by reduction in social pain. Notably, the immediate effect of acetaminophen was specific to social pain rather than social anxiety. Results were discussed in the context of literature on the etiology of social anxiety and social pain. Future directions were suggested. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  17. Search for Hidden Particles (SHiP): a new experiment proposal

    NASA Astrophysics Data System (ADS)

    De Lellis, G.

    2015-06-01

    Searches for new physics with accelerators are being performed at the LHC, looking for high massive particles coupled to matter with ordinary strength. We propose a new experimental facility meant to search for very weakly coupled particles in the few GeV mass domain. The existence of such particles, foreseen in different theoretical models beyond the Standard Model, is largely unexplored from the experimental point of view. A beam dump facility, built at CERN in the north area, using 400 GeV protons is a copious factory of charmed hadrons and could be used to probe the existence of such particles. The beam dump is also an ideal source of tau neutrinos, the less known particle in the Standard Model. In particular, tau anti-neutrinos have not been observed so far. We therefore propose an experiment to search for hidden particles and study tau neutrino physics at the same time.

  18. Trend Watching: Why Are Women Shying Away from Business Careers

    ERIC Educational Resources Information Center

    Giancola, Frank

    2006-01-01

    Recent research indicates that a record number of women today are shunning MBA programs and are looking for careers outside of the corporate business world. In this article, the author presents the findings of recent studies on this trend and examines how higher education can tap into the ever-expanding talent pool of highly qualified candidates…

  19. [On the temporality of delusional perception].

    PubMed

    Oka, Kazutaro

    2011-01-01

    From a descriptive-phenomenological point of view, Huber and Gross differentiated delusional perception with and without concrete abnormal meanings from each other. The latter was regarded as "prozesshaft" and not understandable even by an anthropological-phenomenological interpretation. In this paper, we anthropologically elucidated a temporality of schizophrenia concerning the delusional perception without concrete abnormal meanings. In considering the distinguishing feature of delusion, we paid attention to the exclusion of chance. Generally speaking, a chance encounter between person A and person B is only actualized when they are situated at the same place at the same time. Furthermore they are surprised by such a chance encounter neither in the past nor in the future, but exactly in the present. In this sense, the temporal aspect of a chance encounter is characterized by an intersubjective synchronicity in the present. No one could intentionally produce a chance encounter with others. It takes place only spontaneously. This kind of spontaneity is in Japanese paraphrased by the word "shi-zen" which could be literally translated into "nature" in English. According to some Japanese linguists the spontaneity of "shi-zen" can not be properly expressed either in the active voice or in the passive voice, but in the middle voice, which the Japanese still often use in everyday conversation. Therefore, a chance encounter is produced in the present by "shi-zen" whose becoming is described in the middle voice and not in the active voice. In a chance encounter, we sometimes seek some hidden meaning. However, because of their spontaneity, chance encounters cannot have reasonable meanings. They occur without any reason in the present. In his/her delusional perception without concrete abnormal meanings, a schizophrenic patient often feels that others do something at the same time as the patient acts. Therefore, the patient is confronted with an intersubjective synchronicity

  20. Growth of health maintenance organisations in Nigeria and the potential for a role in promoting universal coverage efforts.

    PubMed

    Onoka, Chima A; Hanson, Kara; Mills, Anne

    2016-08-01

    There has been growing interest in the potential for private health insurance (PHI) and private organisations to contribute to universal health coverage (UHC). Yet evidence from low and middle income countries remains very thin. This paper examines the evolution of health maintenance organisations (HMOs) in Nigeria, the nature of the PHI plans and social health insurance (SHI) programmes and their performance, and the implications of their business practices for providing PHI and UHC-related SHI programmes. An embedded case study design was used with multiple subunits of analysis (individual HMOs and the HMO industry) and mixed (qualitative and quantitative) methods, and the study was guided by the structure-conduct-performance paradigm that has its roots in the neo-classical theory of the firm. Quantitative data collection and 35 in-depth interviews were carried out between October 2012 to July 2013. Although HMOs first emerged in Nigeria to supply PHI, their expansion was driven by their role as purchasers in the government's national health insurance scheme that finances SHI programmes, and facilitated by a weak accreditation system. HMOs' characteristics distinguish the market they operate in as monopolistically competitive, and HMOs as multiproduct firms operating multiple risk pools through parallel administrative systems. The considerable product differentiation and consequent risk selection by private insurers promote inefficiencies. Where HMOs and similar private organisations play roles in health financing systems, effective regulatory institutions and mandates must be established to guide their behaviours towards attainment of public health goals and to identify and control undesirable business practices. Lessons are drawn for policy makers and programme implementers especially in those low and middle-income countries considering the use of private organisations in their health financing systems. Copyright © 2016 Elsevier Ltd. All rights reserved.