36 CFR 906.5 - Administration of affirmative action plan.

Code of Federal Regulations, 2011 CFR

2011-07-01

... CORPORATION AFFIRMATIVE ACTION POLICY AND PROCEDURE Development Program § 906.5 Administration of affirmative action plan. (a) The developer shall appoint an Affirmative Action Officer, and for projects exceeding $10 million in cost, the person appointed must have affirmative action as a primary responsibility. (b...

36 CFR 906.5 - Administration of affirmative action plan.

Code of Federal Regulations, 2010 CFR

2010-07-01

... CORPORATION AFFIRMATIVE ACTION POLICY AND PROCEDURE Development Program § 906.5 Administration of affirmative action plan. (a) The developer shall appoint an Affirmative Action Officer, and for projects exceeding $10 million in cost, the person appointed must have affirmative action as a primary responsibility. (b...

40 CFR 77.4 - Administrator's action on proposed offset plans.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 17 2013-07-01 2013-07-01 false Administrator's action on proposed offset plans. 77.4 Section 77.4 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) EXCESS EMISSIONS § 77.4 Administrator's action on proposed offset plans. (a...

40 CFR 78.6 - Action on petition for administrative review.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 17 2013-07-01 2013-07-01 false Action on petition for administrative review. 78.6 Section 78.6 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPEAL PROCEDURES § 78.6 Action on petition for administrative review. (a) If no...

32 CFR 513.3 - Administrative and punitive actions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 3 2010-07-01 2010-07-01 true Administrative and punitive actions. 513.3 Section 513.3 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY AID OF CIVIL AUTHORITIES AND PUBLIC RELATIONS INDEBTEDNESS OF MILITARY PERSONNEL § 513.3 Administrative and punitive...

45 CFR 689.8 - Interim administrative actions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... RESEARCH MISCONDUCT § 689.8 Interim administrative actions. (a) After an inquiry or during an external or... misconduct. Such an order will normally be issued on recommendation from OIG and in consultation with the...

45 CFR 689.8 - Interim administrative actions.

Code of Federal Regulations, 2012 CFR

2012-10-01

... RESEARCH MISCONDUCT § 689.8 Interim administrative actions. (a) After an inquiry or during an external or... misconduct. Such an order will normally be issued on recommendation from OIG and in consultation with the...

45 CFR 689.8 - Interim administrative actions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... RESEARCH MISCONDUCT § 689.8 Interim administrative actions. (a) After an inquiry or during an external or... misconduct. Such an order will normally be issued on recommendation from OIG and in consultation with the...

45 CFR 689.8 - Interim administrative actions.

Code of Federal Regulations, 2013 CFR

2013-10-01

... RESEARCH MISCONDUCT § 689.8 Interim administrative actions. (a) After an inquiry or during an external or... misconduct. Such an order will normally be issued on recommendation from OIG and in consultation with the...

45 CFR 689.8 - Interim administrative actions.

Code of Federal Regulations, 2014 CFR

2014-10-01

... RESEARCH MISCONDUCT § 689.8 Interim administrative actions. (a) After an inquiry or during an external or... misconduct. Such an order will normally be issued on recommendation from OIG and in consultation with the...

42 CFR 8.34 - Court review of final administrative action; exhaustion of administrative remedies.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 42 Public Health 1 2013-10-01 2013-10-01 false Court review of final administrative action; exhaustion of administrative remedies. 8.34 Section 8.34 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS CERTIFICATION OF OPIOID TREATMENT PROGRAMS Procedures for...

42 CFR 8.34 - Court review of final administrative action; exhaustion of administrative remedies.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 42 Public Health 1 2012-10-01 2012-10-01 false Court review of final administrative action; exhaustion of administrative remedies. 8.34 Section 8.34 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS CERTIFICATION OF OPIOID TREATMENT PROGRAMS Procedures for...

42 CFR 8.34 - Court review of final administrative action; exhaustion of administrative remedies.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 42 Public Health 1 2014-10-01 2014-10-01 false Court review of final administrative action; exhaustion of administrative remedies. 8.34 Section 8.34 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS CERTIFICATION OF OPIOID TREATMENT PROGRAMS Procedures for...

Key Actions of Successful Summer Research Mentors

ERIC Educational Resources Information Center

Raman, D. Raj; Geisinger, Brandi N.; Kemis, Mari R.; de la Mora, Arlene

2016-01-01

Summer research opportunities for undergraduates, such as those supported by the National Science Foundation's Research Experience for Undergraduates (REU) program, can be critical experiences that help persuade students to pursue research through graduate studies. Studies analyzing the key actions of successful mentors are scarce. The goal of…

40 CFR 300.820 - Administrative record file for a removal action.

Code of Federal Regulations, 2010 CFR

2010-07-01

... SUBSTANCES POLLUTION CONTINGENCY PLAN Administrative Record for Selection of Response Action § 300.820 Administrative record file for a removal action. (a) If, based on the site evaluation, the lead agency determines... public comment. At such time, the lead agency shall publish in a major local newspaper of general...

40 CFR 23.2 - Timing of Administrator's action under Clean Water Act.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 1 2013-07-01 2013-07-01 false Timing of Administrator's action under Clean Water Act. 23.2 Section 23.2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL JUDICIAL REVIEW UNDER EPA-ADMINISTERED STATUTES § 23.2 Timing of Administrator's action under Clean Water Act. Unless the Administrator otherwise...

21 CFR 10.45 - Court review of final administrative action; exhaustion of administrative remedies.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 12. (b) A request that the Commissioner take or refrain from taking any form of administrative action... review of final agency action; and (iii) It is not appropriate to move to dismiss a suit for... that it is an unconsented suit against the United States if the defect could be cured by amending the...

21 CFR 10.45 - Court review of final administrative action; exhaustion of administrative remedies.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 12. (b) A request that the Commissioner take or refrain from taking any form of administrative action... review of final agency action; and (iii) It is not appropriate to move to dismiss a suit for... that it is an unconsented suit against the United States if the defect could be cured by amending the...

21 CFR 10.45 - Court review of final administrative action; exhaustion of administrative remedies.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 12. (b) A request that the Commissioner take or refrain from taking any form of administrative action... review of final agency action; and (iii) It is not appropriate to move to dismiss a suit for... that it is an unconsented suit against the United States if the defect could be cured by amending the...

21 CFR 10.45 - Court review of final administrative action; exhaustion of administrative remedies.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 12. (b) A request that the Commissioner take or refrain from taking any form of administrative action... review of final agency action; and (iii) It is not appropriate to move to dismiss a suit for... that it is an unconsented suit against the United States if the defect could be cured by amending the...

12 CFR 615.5361 - Relation to other administrative actions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Relation to other administrative actions. 615.5361 Section 615.5361 Banks and Banking FARM CREDIT ADMINISTRATION FARM CREDIT SYSTEM FUNDING AND FISCAL AFFAIRS, LOAN POLICIES AND OPERATIONS, AND FUNDING OPERATIONS Issuance of a Capital Directive...

40 CFR 23.2 - Timing of Administrator's action under Clean Water Act.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 1 2012-07-01 2012-07-01 false Timing of Administrator's action under Clean Water Act. 23.2 Section 23.2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL JUDICIAL REVIEW UNDER EPA-ADMINISTERED STATUTES § 23.2 Timing of Administrator's action under Clean Water...

40 CFR 23.2 - Timing of Administrator's action under Clean Water Act.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Timing of Administrator's action under Clean Water Act. 23.2 Section 23.2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL JUDICIAL REVIEW UNDER EPA-ADMINISTERED STATUTES § 23.2 Timing of Administrator's action under Clean Water...

40 CFR 23.2 - Timing of Administrator's action under Clean Water Act.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 1 2014-07-01 2014-07-01 false Timing of Administrator's action under Clean Water Act. 23.2 Section 23.2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL JUDICIAL REVIEW UNDER EPA-ADMINISTERED STATUTES § 23.2 Timing of Administrator's action under Clean Water...

40 CFR 23.2 - Timing of Administrator's action under Clean Water Act.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Timing of Administrator's action under Clean Water Act. 23.2 Section 23.2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL JUDICIAL REVIEW UNDER EPA-ADMINISTERED STATUTES § 23.2 Timing of Administrator's action under Clean Water...

42 CFR 93.407 - HHS administrative actions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... RESEARCH MISCONDUCT Responsibilities of the U.S. Department of Health and Human Services Research Misconduct Issues § 93.407 HHS administrative actions. (a) In response to a research misconduct proceeding... Subparts 9.4 and 309.4, or both. (b) In connection with findings of research misconduct, HHS also may seek...

42 CFR 8.34 - Court review of final administrative action; exhaustion of administrative remedies.

Code of Federal Regulations, 2010 CFR

2010-10-01

... HEALTH AND HUMAN SERVICES GENERAL PROVISIONS CERTIFICATION OF OPIOID TREATMENT PROGRAMS Procedures for... Withdrawal of Approval of an Accreditation Body § 8.34 Court review of final administrative action...

42 CFR 8.34 - Court review of final administrative action; exhaustion of administrative remedies.

Code of Federal Regulations, 2011 CFR

2011-10-01

... HEALTH AND HUMAN SERVICES GENERAL PROVISIONS CERTIFICATION OF OPIOID TREATMENT PROGRAMS Procedures for... Withdrawal of Approval of an Accreditation Body § 8.34 Court review of final administrative action...

23 CFR 810.208 - Action by the Federal Highway Administrator.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 23 Highways 1 2014-04-01 2014-04-01 false Action by the Federal Highway Administrator. 810.208 Section 810.208 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PUBLIC TRANSPORTATION MASS TRANSIT AND SPECIAL USE HIGHWAY PROJECTS Making Highway Rights-of-Way Available for Mass...

23 CFR 810.208 - Action by the Federal Highway Administrator.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 23 Highways 1 2013-04-01 2013-04-01 false Action by the Federal Highway Administrator. 810.208 Section 810.208 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PUBLIC TRANSPORTATION MASS TRANSIT AND SPECIAL USE HIGHWAY PROJECTS Making Highway Rights-of-Way Available for Mass...

23 CFR 810.208 - Action by the Federal Highway Administrator.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 23 Highways 1 2012-04-01 2012-04-01 false Action by the Federal Highway Administrator. 810.208 Section 810.208 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PUBLIC TRANSPORTATION MASS TRANSIT AND SPECIAL USE HIGHWAY PROJECTS Making Highway Rights-of-Way Available for Mass...

20 CFR 408.1003 - Which administrative actions are initial determinations?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Which administrative actions are initial determinations? 408.1003 Section 408.1003 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SPECIAL BENEFITS FOR...) Our calculation of the amount of change in your federally administered State recognition payment...

Key Action Items for the Stem Cell Field: Looking Ahead to 2014

PubMed Central

Knoepfler, Paul S.

2013-01-01

Abstract The stem cell field is at a critical juncture in late 2013. We find ourselves buoyed by building momentum for both transformative basic science discoveries and clinical translation of stem cells. Cellular reprogramming has given the field exciting new avenues as well. The overall prospect of novel stem cell–based therapies becoming a reality for patients in the coming years has never seemed higher. At the same time, we face serious challenges. Some of these challenges, such as stem cell tourism, are familiar to us, although even those are evolving in ways that require adaptability and action by the stem cell field. Other new challenges are also emerging, including an urgent need for formal physician training in stem cells, regulatory compliance balanced with innovation and U.S. Food and Drug Administration reform, and savvy educational outreach. Looking ahead to 2014, both the challenges and opportunities for the stem cell field require a proactive, thoughtful approach to maximize the potential for a positive impact from stem cell advances. In this study, I discuss the key action items for the field as we look ahead to the coming year and beyond. PMID:24147571

Key action items for the stem cell field: looking ahead to 2014.

PubMed

Knoepfler, Paul S

2013-12-01

The stem cell field is at a critical juncture in late 2013. We find ourselves buoyed by building momentum for both transformative basic science discoveries and clinical translation of stem cells. Cellular reprogramming has given the field exciting new avenues as well. The overall prospect of novel stem cell-based therapies becoming a reality for patients in the coming years has never seemed higher. At the same time, we face serious challenges. Some of these challenges, such as stem cell tourism, are familiar to us, although even those are evolving in ways that require adaptability and action by the stem cell field. Other new challenges are also emerging, including an urgent need for formal physician training in stem cells, regulatory compliance balanced with innovation and U.S. Food and Drug Administration reform, and savvy educational outreach. Looking ahead to 2014, both the challenges and opportunities for the stem cell field require a proactive, thoughtful approach to maximize the potential for a positive impact from stem cell advances. In this study, I discuss the key action items for the field as we look ahead to the coming year and beyond.

24 CFR 25.6 - Violations creating grounds for administrative action.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Violations creating grounds for administrative action. 25.6 Section 25.6 Housing and Urban Development Office of the Secretary, Department of Housing and Urban Development MORTGAGEE REVIEW BOARD § 25.6 Violations creating grounds for administrative...

21 CFR 516.123 - Informal conferences regarding agency administrative actions.

Code of Federal Regulations, 2010 CFR

2010-04-01

... exemption, determining that a qualified expert panel does not meet the selection criteria, denying a request... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Informal conferences regarding agency administrative actions. 516.123 Section 516.123 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH...

32 CFR 516.66 - Administrative and contractual actions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 3 2010-07-01 2010-07-01 true Administrative and contractual actions. 516.66 Section 516.66 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY AID OF CIVIL AUTHORITIES AND PUBLIC RELATIONS LITIGATION Remedies in Procurement Fraud and Corruption § 516.66...

75 FR 43537 - Mortgagee Review Board: Administrative Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-26

...., Fountain Valley, CA. 469. Ironwood Lending, Inc., Phoenix, AZ. 470. IVC Mortgage Group, Inc., Des Plaines..., connected, or had authorization from HUD for its Web site. 3. Americare Investment Group, Inc. d/b/a Premier... Notice of Administrative Action to Americare Investment Group, Inc. (Americare) permanently withdrawing...

32 CFR 516.66 - Administrative and contractual actions.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 3 2011-07-01 2009-07-01 true Administrative and contractual actions. 516.66 Section 516.66 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY AID OF CIVIL AUTHORITIES AND PUBLIC RELATIONS LITIGATION Remedies in Procurement Fraud and Corruption § 516.66...

Human action recognition based on spatial-temporal descriptors using key poses

NASA Astrophysics Data System (ADS)

Hu, Shuo; Chen, Yuxin; Wang, Huaibao; Zuo, Yaqing

2014-11-01

Human action recognition is an important area of pattern recognition today due to its direct application and need in various occasions like surveillance and virtual reality. In this paper, a simple and effective human action recognition method is presented based on the key poses of human silhouette and the spatio-temporal feature. Firstly, the contour points of human silhouette have been gotten, and the key poses are learned by means of K-means clustering based on the Euclidean distance between each contour point and the centre point of the human silhouette, and then the type of each action is labeled for further match. Secondly, we obtain the trajectories of centre point of each frame, and create a spatio-temporal feature value represented by W to describe the motion direction and speed of each action. The value W contains the information of location and temporal order of each point on the trajectories. Finally, the matching stage is performed by comparing the key poses and W between training sequences and test sequences, the nearest neighbor sequences is found and its label supplied the final result. Experiments on the public available Weizmann datasets show the proposed method can improve accuracy by distinguishing amphibious poses and increase suitability for real-time applications by reducing the computational cost.

40 CFR 23.7 - Timing of Administrator's action under Safe Drinking Water Act.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 1 2013-07-01 2013-07-01 false Timing of Administrator's action under Safe Drinking Water Act. 23.7 Section 23.7 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL JUDICIAL REVIEW UNDER EPA-ADMINISTERED STATUTES § 23.7 Timing of Administrator's action under Safe Drinking Water Act. Unless the...

Help Teachers Engage Students: Action Tools for Administrators

ERIC Educational Resources Information Center

Brinkman, Annette; Forlini, Gary; Williams, Ellen

2009-01-01

This unique, hands-on reference for school administrators offers guidelines for effective student engagement as well as reproducible action tools that will enable you to: (1) Identify and share "The Big Eight Student Engagement Strategies" with your teachers; (2) Promote teacher growth and provide support for new and/or struggling teachers; (3)…

42 CFR 93.501 - Opportunity to contest findings of research misconduct and administrative actions.

Code of Federal Regulations, 2012 CFR

2012-10-01

... misconduct and administrative actions. 93.501 Section 93.501 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT... RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions General Information § 93.501 Opportunity to...

42 CFR 93.501 - Opportunity to contest findings of research misconduct and administrative actions.

Code of Federal Regulations, 2013 CFR

2013-10-01

... misconduct and administrative actions. 93.501 Section 93.501 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT... RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions General Information § 93.501 Opportunity to...

42 CFR 93.501 - Opportunity to contest findings of research misconduct and administrative actions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... misconduct and administrative actions. 93.501 Section 93.501 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT... RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions General Information § 93.501 Opportunity to...

42 CFR 93.501 - Opportunity to contest findings of research misconduct and administrative actions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... misconduct and administrative actions. 93.501 Section 93.501 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT... RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions General Information § 93.501 Opportunity to...

42 CFR 93.501 - Opportunity to contest findings of research misconduct and administrative actions.

Code of Federal Regulations, 2014 CFR

2014-10-01

... misconduct and administrative actions. 93.501 Section 93.501 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT... RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions General Information § 93.501 Opportunity to...

40 CFR 300.815 - Administrative record file for a remedial action.

Code of Federal Regulations, 2010 CFR

2010-07-01

... SUBSTANCES POLLUTION CONTINGENCY PLAN Administrative Record for Selection of Response Action § 300.815... investigation phase. At such time, the lead agency shall publish in a major local newspaper of general circulation a notice of the availability of the administrative record file. (b) The lead agency shall provide...

20 CFR 408.1004 - Which administrative actions are not initial determinations?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Which administrative actions are not initial determinations? 408.1004 Section 408.1004 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SPECIAL BENEFITS FOR... federally administered State recognition payments due to a State-initiated mass change, as defined in § 408...

Agri-Environmental Resource Management by Large-Scale Collective Action: Determining KEY Success Factors

ERIC Educational Resources Information Center

Uetake, Tetsuya

2015-01-01

Purpose: Large-scale collective action is necessary when managing agricultural natural resources such as biodiversity and water quality. This paper determines the key factors to the success of such action. Design/Methodology/Approach: This paper analyses four large-scale collective actions used to manage agri-environmental resources in Canada and…

The relative advantages of criminal versus administrative environmental enforcement actions in Israel.

PubMed

Tal, Alon; Aharon, Yaara; Yuhas-Peled, Hadar

2010-04-01

Most environmental enforcement programs have separate criminal and administrative procedures for addressing violations. Pitting "criminal"versus"administrative" enforcement as mutually exclusive alternatives constitutes a "false dilemma". Clearly, the government response should be influenced by the severity of pollution and the specific circumstances of the polluter. Yet, policy makers seeking to improve environmental compliance need to have a clearer picture about the merits of each approach and their relative effectiveness. This research empirically assesses the effectiveness of criminal versus administrative enforcement activities in Israel. After considering the philosophical implications associated with each regulatory approach, the results of a year-long study are presented. A series of performance indicators are utilized, with particular weight on compliance status in the field, to assess the condition of environmental violations several years subsequent to completion of enforcement activities. The state of 100 violations of air, water and hazardous materials laws that had been addressed through the criminal process were matched with results of comparable violations, against which administrative actions were taken. Results suggest that while criminal enforcement is a longer process, compliance following these actions was significantly greater than in administrative enforcement cases. The findings also underline the significance of a systematic follow-up system for tracking violations after enforcement actions are complete. Finally, the study confirms the benefits of targeted assistance to improve compliance among violators of environmental standards.

40 CFR 23.8 - Timing of Administrator's action under Uranium Mill Tailings Radiation Control Act of 1978.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Timing of Administrator's action under Uranium Mill Tailings Radiation Control Act of 1978. 23.8 Section 23.8 Protection of Environment... Administrator's action under Uranium Mill Tailings Radiation Control Act of 1978. Unless the Administrator...

40 CFR 23.8 - Timing of Administrator's action under Uranium Mill Tailings Radiation Control Act of 1978.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 1 2013-07-01 2013-07-01 false Timing of Administrator's action under Uranium Mill Tailings Radiation Control Act of 1978. 23.8 Section 23.8 Protection of Environment... Administrator's action under Uranium Mill Tailings Radiation Control Act of 1978. Unless the Administrator...

40 CFR 23.8 - Timing of Administrator's action under Uranium Mill Tailings Radiation Control Act of 1978.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 1 2014-07-01 2014-07-01 false Timing of Administrator's action under Uranium Mill Tailings Radiation Control Act of 1978. 23.8 Section 23.8 Protection of Environment... Administrator's action under Uranium Mill Tailings Radiation Control Act of 1978. Unless the Administrator...

40 CFR 23.8 - Timing of Administrator's action under Uranium Mill Tailings Radiation Control Act of 1978.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 1 2012-07-01 2012-07-01 false Timing of Administrator's action under Uranium Mill Tailings Radiation Control Act of 1978. 23.8 Section 23.8 Protection of Environment... Administrator's action under Uranium Mill Tailings Radiation Control Act of 1978. Unless the Administrator...

40 CFR 23.8 - Timing of Administrator's action under Uranium Mill Tailings Radiation Control Act of 1978.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Timing of Administrator's action under Uranium Mill Tailings Radiation Control Act of 1978. 23.8 Section 23.8 Protection of Environment... Administrator's action under Uranium Mill Tailings Radiation Control Act of 1978. Unless the Administrator...

From Headline to Hard Grind: The Importance of Understanding Public Administration in Achieving Health OutcomesComment on "Understanding the Role of Public Administration in Implementing Action on the Social Determinants of Health and Health Inequities".

PubMed

O'Flynn, Janine

2016-04-30

Many public policy programs fail to translate ambitious headlines to on-the-ground action. The reasons for this are many and varied, but for public administration and management scholars a large part of the gap between ambition and achievement is the challenge associated with the operation of the machinery of government itself, and how it relates to the other parties that it relies on to fulfill these outcomes. In their article, Carey and Friel set out key reasons why public health scholars should seek to better understand important ideas in public administration. In commenting on their contribution, I draw out two critical questions that are raised by this discussion: (i) what are boundaries and what forms do they take? and (ii) why work across boundaries? Expanding on these key questions extends the points made by Carey and Friel on the importance of understanding public administration and will better place public health scholars and practitioners to realise health outcomes. © 2016 by Kerman University of Medical Sciences.

40 CFR 23.10 - Timing of Administrator's action under the Federal Food, Drug, and Cosmetic Act.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Timing of Administrator's action under the Federal Food, Drug, and Cosmetic Act. 23.10 Section 23.10 Protection of Environment ENVIRONMENTAL... action under the Federal Food, Drug, and Cosmetic Act. Unless the Administrator otherwise explicitly...

40 CFR 23.10 - Timing of Administrator's action under the Federal Food, Drug, and Cosmetic Act.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 1 2012-07-01 2012-07-01 false Timing of Administrator's action under the Federal Food, Drug, and Cosmetic Act. 23.10 Section 23.10 Protection of Environment ENVIRONMENTAL... action under the Federal Food, Drug, and Cosmetic Act. Unless the Administrator otherwise explicitly...

40 CFR 23.10 - Timing of Administrator's action under the Federal Food, Drug, and Cosmetic Act.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Timing of Administrator's action under the Federal Food, Drug, and Cosmetic Act. 23.10 Section 23.10 Protection of Environment ENVIRONMENTAL... action under the Federal Food, Drug, and Cosmetic Act. Unless the Administrator otherwise explicitly...

40 CFR 23.10 - Timing of Administrator's action under the Federal Food, Drug, and Cosmetic Act.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 1 2014-07-01 2014-07-01 false Timing of Administrator's action under the Federal Food, Drug, and Cosmetic Act. 23.10 Section 23.10 Protection of Environment ENVIRONMENTAL... action under the Federal Food, Drug, and Cosmetic Act. Unless the Administrator otherwise explicitly...

40 CFR 23.10 - Timing of Administrator's action under the Federal Food, Drug, and Cosmetic Act.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 1 2013-07-01 2013-07-01 false Timing of Administrator's action under the Federal Food, Drug, and Cosmetic Act. 23.10 Section 23.10 Protection of Environment ENVIRONMENTAL... action under the Federal Food, Drug, and Cosmetic Act. Unless the Administrator otherwise explicitly...

40 CFR 23.7 - Timing of Administrator's action under Safe Drinking Water Act.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Safe Drinking Water Act. 23.7 Section 23.7 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL JUDICIAL REVIEW UNDER EPA-ADMINISTERED STATUTES § 23.7 Timing of Administrator's action under Safe Drinking Water Act. Unless the Administrator otherwise explicitly provides in a particular promulgation...

40 CFR 23.7 - Timing of Administrator's action under Safe Drinking Water Act.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Safe Drinking Water Act. 23.7 Section 23.7 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL JUDICIAL REVIEW UNDER EPA-ADMINISTERED STATUTES § 23.7 Timing of Administrator's action under Safe Drinking Water Act. Unless the Administrator otherwise explicitly provides in a particular promulgation...

40 CFR 23.9 - Timing of Administrator's action under the Atomic Energy Act.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 1 2014-07-01 2014-07-01 false Timing of Administrator's action under the Atomic Energy Act. 23.9 Section 23.9 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Atomic Energy Act. Unless the Administrator otherwise explicitly provides in a particular order, the time...

40 CFR 23.9 - Timing of Administrator's action under the Atomic Energy Act.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Timing of Administrator's action under the Atomic Energy Act. 23.9 Section 23.9 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Atomic Energy Act. Unless the Administrator otherwise explicitly provides in a particular order, the time...

40 CFR 23.9 - Timing of Administrator's action under the Atomic Energy Act.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Timing of Administrator's action under the Atomic Energy Act. 23.9 Section 23.9 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Atomic Energy Act. Unless the Administrator otherwise explicitly provides in a particular order, the time...

40 CFR 23.9 - Timing of Administrator's action under the Atomic Energy Act.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 1 2012-07-01 2012-07-01 false Timing of Administrator's action under the Atomic Energy Act. 23.9 Section 23.9 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Atomic Energy Act. Unless the Administrator otherwise explicitly provides in a particular order, the time...

40 CFR 23.9 - Timing of Administrator's action under the Atomic Energy Act.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 1 2013-07-01 2013-07-01 false Timing of Administrator's action under the Atomic Energy Act. 23.9 Section 23.9 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Atomic Energy Act. Unless the Administrator otherwise explicitly provides in a particular order, the time...

32 CFR 636.5 - Army administrative actions against intoxicated drivers.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 4 2010-07-01 2010-07-01 true Army administrative actions against intoxicated drivers. 636.5 Section 636.5 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) LAW ENFORCEMENT AND CRIMINAL INVESTIGATIONS MOTOR VEHICLE TRAFFIC SUPERVISION (SPECIFIC INSTALLATIONS) Fort Stewart, Georgia § 636.5...

15 CFR 720.3 - Final decision on administrative action denying export privileges.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE CHEMICAL WEAPONS CONVENTION REGULATIONS DENIAL OF EXPORT PRIVILEGES § 720.3 Final decision on administrative action...

15 CFR 720.3 - Final decision on administrative action denying export privileges.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE CHEMICAL WEAPONS CONVENTION REGULATIONS DENIAL OF EXPORT PRIVILEGES § 720.3 Final decision on administrative action...

78 FR 277 - Food and Drug Administration Actions Related to Nicotine Replacement Therapies and Smoking...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-03

... Dependence; Public Hearing; Extension of Comment Period AGENCY: Food and Drug Administration, HHS. ACTION: Notification of public hearing; Extension of comment period. SUMMARY: The Food and Drug Administration (FDA) is... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration 21 CFR Part 15 [Docket No...

15 CFR 720.2 - Initiation of administrative action denying export privileges.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Initiation of administrative action denying export privileges. 720.2 Section 720.2 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE CHEMICAL WEAPONS...

15 CFR 720.2 - Initiation of administrative action denying export privileges.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 15 Commerce and Foreign Trade 2 2011-01-01 2011-01-01 false Initiation of administrative action denying export privileges. 720.2 Section 720.2 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE CHEMICAL WEAPONS...

Real-Time Biologically Inspired Action Recognition from Key Poses Using a Neuromorphic Architecture.

PubMed

Layher, Georg; Brosch, Tobias; Neumann, Heiko

2017-01-01

Intelligent agents, such as robots, have to serve a multitude of autonomous functions. Examples are, e.g., collision avoidance, navigation and route planning, active sensing of its environment, or the interaction and non-verbal communication with people in the extended reach space. Here, we focus on the recognition of the action of a human agent based on a biologically inspired visual architecture of analyzing articulated movements. The proposed processing architecture builds upon coarsely segregated streams of sensory processing along different pathways which separately process form and motion information (Layher et al., 2014). Action recognition is performed in an event-based scheme by identifying representations of characteristic pose configurations (key poses) in an image sequence. In line with perceptual studies, key poses are selected unsupervised utilizing a feature-driven criterion which combines extrema in the motion energy with the horizontal and the vertical extendedness of a body shape. Per class representations of key pose frames are learned using a deep convolutional neural network consisting of 15 convolutional layers. The network is trained using the energy-efficient deep neuromorphic networks ( Eedn ) framework (Esser et al., 2016), which realizes the mapping of the trained synaptic weights onto the IBM Neurosynaptic System platform (Merolla et al., 2014). After the mapping, the trained network achieves real-time capabilities for processing input streams and classify input images at about 1,000 frames per second while the computational stages only consume about 70 mW of energy (without spike transduction). Particularly regarding mobile robotic systems, a low energy profile might be crucial in a variety of application scenarios. Cross-validation results are reported for two different datasets and compared to state-of-the-art action recognition approaches. The results demonstrate, that (I) the presented approach is on par with other key pose based

Real-Time Biologically Inspired Action Recognition from Key Poses Using a Neuromorphic Architecture

PubMed Central

Layher, Georg; Brosch, Tobias; Neumann, Heiko

2017-01-01

Intelligent agents, such as robots, have to serve a multitude of autonomous functions. Examples are, e.g., collision avoidance, navigation and route planning, active sensing of its environment, or the interaction and non-verbal communication with people in the extended reach space. Here, we focus on the recognition of the action of a human agent based on a biologically inspired visual architecture of analyzing articulated movements. The proposed processing architecture builds upon coarsely segregated streams of sensory processing along different pathways which separately process form and motion information (Layher et al., 2014). Action recognition is performed in an event-based scheme by identifying representations of characteristic pose configurations (key poses) in an image sequence. In line with perceptual studies, key poses are selected unsupervised utilizing a feature-driven criterion which combines extrema in the motion energy with the horizontal and the vertical extendedness of a body shape. Per class representations of key pose frames are learned using a deep convolutional neural network consisting of 15 convolutional layers. The network is trained using the energy-efficient deep neuromorphic networks (Eedn) framework (Esser et al., 2016), which realizes the mapping of the trained synaptic weights onto the IBM Neurosynaptic System platform (Merolla et al., 2014). After the mapping, the trained network achieves real-time capabilities for processing input streams and classify input images at about 1,000 frames per second while the computational stages only consume about 70 mW of energy (without spike transduction). Particularly regarding mobile robotic systems, a low energy profile might be crucial in a variety of application scenarios. Cross-validation results are reported for two different datasets and compared to state-of-the-art action recognition approaches. The results demonstrate, that (I) the presented approach is on par with other key pose based

Errors in preparation and administration of parenteral drugs in neonatology: evaluation and corrective actions.

PubMed

Hasni, Nesrine; Ben Hamida, Emira; Ben Jeddou, Khouloud; Ben Hamida, Sarra; Ayadi, Imene; Ouahchi, Zeineb; Marrakchi, Zahra

2016-12-01

The medication iatrogenic risk is quite unevaluated in neonatology Objective: Assessment of errors that occurred during the preparation and administration of injectable medicines in a neonatal unit in order to implement corrective actions to reduce the occurrence of these errors. A prospective, observational study was performed in a neonatal unit over a period of one month. The practice of preparing and administering injectable medications were identified through a standardized data collection form. These practices were compared with summaries of the characteristics of each product (RCP) and the bibliography. One hundred preparations were observed of 13 different drugs. 85 errors during preparations and administration steps were detected. These errors were divided into preparation errors in 59% of cases such as changing the dilution protocol (32%), the use of bad solvent (11%) and administration errors in 41% of cases as errors timing of administration (18%) or omission of administration (9%). This study showed a high rate of errors during stages of preparation and administration of injectable drugs. In order to optimize the care of newborns and reduce the risk of medication errors, corrective actions have been implemented through the establishment of a quality assurance system which consisted of the development of injectable drugs preparation procedures, the introduction of a labeling system and staff training.

Nursing Academic Administrators' Lived Experiences With Incivility and Bullying From Faculty: Consequences and Outcomes Demanding Action.

PubMed

LaSala, Kathleen B; Wilson, Vicki; Sprunk, Elizabeth

2016-01-01

There are an increasing number of nursing academic administrators who identify themselves as victims of faculty incivility. This study examined experiences that academic administrators encountered with faculty incivility using a phenomenological research design. Three major themes emerged: faculty inappropriate behaviors, consequences of faculty behaviors on administrator targets, and administrators call for action. Findings revealed that incivility had devastating effects on administrators personally and professionally.

School Administrator Perceptions of Cyberbullying Facilitators and Barriers to Preventive Action: A Qualitative Study.

PubMed

Young, Rachel; Tully, Melissa; Ramirez, Marizen

2017-06-01

Schools are often held responsible for preventing or addressing cyberbullying, yet little is known about school administrator perceptions of cyberbullying and the challenges they face in addressing this public health issue. The goal of this study is to examine school administrators' perceptions of the facilitators of cyberbullying and barriers to primary and secondary prevention strategies. Public school administrators ( N = 36) participated in in-depth interviews about bullying and discussed their experiences with cyberbullying and their perceptions of cyberbullying facilitators and barriers to prevention. Three main themes arose from the analysis: (1) cyberbullying as a major challenge; (2) facilitators of cyberbullying and barriers to preventive action, including parents and technology; and (3) prevention efforts, including unclear jurisdiction for action, primary versus secondary prevention efforts, and technology attributes that facilitate school response to bullying. Although administrators perceive cyberbullying as a major challenge facing their schools, they are often unsure about appropriate primary and secondary prevention efforts. Relationships with parents and police complicate response and prevention as schools attempt to navigate unclear jurisdiction. Additionally, technology presents a challenge to schools because it is seen as an enabler of cyberbullying, a facilitator of prevention, and a necessary part of education efforts. Lack of research on prevention strategies, parents' knowledge and attitudes, and confusion about responsibility for addressing cyberbullying are barriers to action. Findings suggest administrators could benefit from additional clarity on which strategies are most effective for primary prevention of cyberbullying, and that prevention strategies should proactively involve parents to promote effective collaboration with schools.

Key Questions on the Obama Administration's 2014 Education Budget Request. Issue Brief

ERIC Educational Resources Information Center

New America Foundation, 2013

2013-01-01

President Obama sent his fiscal year 2014 budget request to Congress on April 10, 2013. The New America Foundation's Education Policy Program released this subsequent issue brief, "Key Questions on the Obama Administration's 2014 Budget Request." Obama's budget request totals $71.2 billion in appropriations funding for the U.S.…

42 CFR 456.524 - Notification of Administrator's action and duration of variance.

Code of Federal Regulations, 2011 CFR

2011-10-01

..., DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS UTILIZATION CONTROL Utilization Review Plans: FFP, Waivers, and Variances for Hospitals and Mental Hospitals Ur Plan: Remote Facility Variances from Time Requirements § 456.524 Notification of Administrator's action and duration of...

Electroporation-delivered transdermal neostigmine in rats: equivalent action to intravenous administration

PubMed Central

Berkó, Szilvia; Szűcs, Kálmán F; Balázs, Boglárka; Csányi, Erzsébet; Varju, Gábor; Sztojkov-Ivanov, Anita; Budai-Szűcs, Mária; Bóta, Judit; Gáspár, Róbert

2016-01-01

Purpose Transdermal electroporation has become one of the most promising noninvasive methods for drug administration, with greatly increased transport of macromolecules through the skin. The cecal-contracting effects of repeated transdermal electroporation delivery and intravenous administration of neostigmine were compared in anesthetized rats. Methods The cecal contractions were detected with implantable strain gauge sensors, and the plasma levels of neostigmine were followed by high-performance liquid chromatography. Results Both intravenously and EP-administered neostigmine (0.2–66.7 μg/kg) increased the cecal contractions in a dose-dependent manner. For both the low doses and the highest dose, the neostigmine plasma concentrations were the same after the two modes of administration, while an insignificantly higher level was observed at a dose of 20 μg/kg after intravenous administration as compared with the electroporation route. The contractile responses did not differ significantly after the two administration routes. Conclusion The results suggest that electroporation-delivered neostigmine elicits action equivalent to that observed after intravenous administration as concerning both time and intensity. Electroporation permits the delivery of even lower doses of water-soluble compounds through the skin, which is very promising for clinical practice. PMID:27274203

42 CFR 457.203 - Administrative and judicial review of action on State plan material.

Code of Federal Regulations, 2010 CFR

2010-10-01

... determines that his or her original decision was incorrect, CMS will pay the State a lump sum equal to any... with the Administrator's action on State plan material under § 457.150 may, within 60 days after... of hearing. Within 30 days after receipt of the request, the Administrator notifies the State of the...

Effect of mode of administration on guaifenesin pharmacokinetics and expectorant action in the rat model.

PubMed

Kagan, Leonid; Lavy, Eran; Hoffman, Amnon

2009-06-01

Guaifenesin is a very commonly used and prescribed oral expectorant drug. However, its mechanism of action is not completely elucidated and the available information is limited. The purpose was to evaluate whether guaifenesin action on respiratory tract secretion is mediated through a reflex stimulation of the gastric mucosa or by the systemic exposure due to the absorption of the drug to the blood circulation. Guaifenesin was administered to rats by various routes: intravenous bolus, oral gavage, and gastric, jejunal or cecal infusions (through surgically implanted catheters). Phenol red respiratory tract secretion (after intraperitoneal or intravenous injection) was used as a marker for degree of expectorant action. Administration of saline by gavage was used as control. Respiratory secretion following oral bolus was approximately 2-fold higher (p<0.05) than that of control. Following IV administration the increase of respiratory secretion did not occur despite the fact that systemic exposure to guaifenesin was 1.5-fold higher than following oral administration. The abdominal surgery was found to eliminate the effect of guaifenesin although it did not change systemic absorption. Guaifenesin was equally absorbed from all parts of the gastrointestinal tract. It was demonstrated that expectorant action of guaifenesin is mediated by stimulation of the gastrointestinal tract and not by the systemic exposure to the drug.

42 CFR 93.408 - Mitigating and aggravating factors in HHS administrative actions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 42 Public Health 1 2011-10-01 2011-10-01 false Mitigating and aggravating factors in HHS administrative actions. 93.408 Section 93.408 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH ASSESSMENTS AND HEALTH EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES...

42 CFR 93.408 - Mitigating and aggravating factors in HHS administrative actions.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 42 Public Health 1 2012-10-01 2012-10-01 false Mitigating and aggravating factors in HHS administrative actions. 93.408 Section 93.408 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH ASSESSMENTS AND HEALTH EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES...

42 CFR 93.408 - Mitigating and aggravating factors in HHS administrative actions.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 42 Public Health 1 2014-10-01 2014-10-01 false Mitigating and aggravating factors in HHS administrative actions. 93.408 Section 93.408 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH ASSESSMENTS AND HEALTH EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES...

42 CFR 93.408 - Mitigating and aggravating factors in HHS administrative actions.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 42 Public Health 1 2013-10-01 2013-10-01 false Mitigating and aggravating factors in HHS administrative actions. 93.408 Section 93.408 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH ASSESSMENTS AND HEALTH EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES...

The use of mode of action information in risk assessment: quantitative key events/dose-response framework for modeling the dose-response for key events.

PubMed

Simon, Ted W; Simons, S Stoney; Preston, R Julian; Boobis, Alan R; Cohen, Samuel M; Doerrer, Nancy G; Fenner-Crisp, Penelope A; McMullin, Tami S; McQueen, Charlene A; Rowlands, J Craig

2014-08-01

The HESI RISK21 project formed the Dose-Response/Mode-of-Action Subteam to develop strategies for using all available data (in vitro, in vivo, and in silico) to advance the next-generation of chemical risk assessments. A goal of the Subteam is to enhance the existing Mode of Action/Human Relevance Framework and Key Events/Dose Response Framework (KEDRF) to make the best use of quantitative dose-response and timing information for Key Events (KEs). The resulting Quantitative Key Events/Dose-Response Framework (Q-KEDRF) provides a structured quantitative approach for systematic examination of the dose-response and timing of KEs resulting from a dose of a bioactive agent that causes a potential adverse outcome. Two concepts are described as aids to increasing the understanding of mode of action-Associative Events and Modulating Factors. These concepts are illustrated in two case studies; 1) cholinesterase inhibition by the pesticide chlorpyrifos, which illustrates the necessity of considering quantitative dose-response information when assessing the effect of a Modulating Factor, that is, enzyme polymorphisms in humans, and 2) estrogen-induced uterotrophic responses in rodents, which demonstrate how quantitative dose-response modeling for KE, the understanding of temporal relationships between KEs and a counterfactual examination of hypothesized KEs can determine whether they are Associative Events or true KEs.

Administrators in Action--Managing Public Monies and Processing Emotion in School Activities: A Teaching Case Study

ERIC Educational Resources Information Center

Tenuto, Penny L.; Gardiner, Mary E.; Yamamoto, Julie K.

2015-01-01

This teaching case describes school administrators in action performing day-to-day leadership tasks, managing public funds in school activities, and interacting with others appropriately. The case focuses on administrative challenges in handling and managing school activity funds. A method for processing emotion is discussed to assist…

Neurohumoral mechanism in the natriuretic action of intracerebroventricular administration of renin.

PubMed

Zavala, Lida; Barbella, Yarisma; Israel, Anita

2004-03-01

Intracerebroventricular (i.v.t.) administration of renin (R) decreases urinary volume and increases urinary sodium excretion. We investigated whether i.v.t.-R-induced natriuresis could be associated with the release of atrial natriuretic peptide (ANP), its interaction with renal ANP-A receptors (ANPR-A) and the subsequent increase of urinary cyclic 3-5 guanosine monophosphate (cGMP). In i.v.t. cannulated rats, the left carotid artery was catheterised with PE-50 tubing for blood collection, renin was injected i.v.t. and arterial blood samples were collected at 0, 2, 5, 10 and 15 minutes of injection, and urinary sodium and cGMP excretion at 1-, 3- and 6-hour periods of urine collection. Plasma ANP levels and urinary cGMP were determined by radioimmunoassay, and each urine sample was analysed for sodium concentration using a flame photometer. Our results demonstrate that i.v.t.-R administration increases plasma ANP levels after two minutes of injection and urinary cGMP concentration at 1-, 3- and 6 hour period of urine collection. The natriuretic action induced by i.v.t.-R was blunted by peripheral administration of anantin, an ANPR-A antagonist. We assessed the role of brain angiotensin II (Ang II) AT1-receptors on the i.v.t.-induced antidiuresis, natriuresis and cGMP urinary excretion, the last as an indirect index of ANP secretion. Blockade of brain Ang II AT1-receptors with losartan (LOS; 120 microg/3 microl, i.v.t.), inhibited the antidiuretic action and blocked the increased urinary sodium and cGMP excretion induced by i.v.t.-R (7.14 mGU/5 microl). The increase in urinary cGMP was independent of nitric oxide synthase stimulation, since L-NAME pre-treatment did not alter the renal actions induced by i.v.t.-R. Our results suggest that there is a link between the brain and the kidney. The activation of brain angiotensinergic neurons and stimulation of AT1- receptors may stimulate the release of ANP to the circulation. The released ANP circulates to the kidneys

20 CFR 667.800 - What actions of the Department may be appealed to the Office of Administrative Law Judges?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false What actions of the Department may be appealed to the Office of Administrative Law Judges? 667.800 Section 667.800 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR ADMINISTRATIVE PROVISIONS UNDER TITLE I OF THE WORKFORCE INVESTMENT ACT Administrative Adjudication...

10 CFR 10.33 - Action by the Deputy Executive Director for Information Services and Administration and Chief...

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 1 2011-01-01 2011-01-01 false Action by the Deputy Executive Director for Information Services and Administration and Chief Information Officer. 10.33 Section 10.33 Energy NUCLEAR REGULATORY... SECURITY INFORMATION OR AN EMPLOYMENT CLEARANCE Procedures § 10.33 Action by the Deputy Executive Director...

10 CFR 10.33 - Action by the Deputy Executive Director for Information Services and Administration and Chief...

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 1 2012-01-01 2012-01-01 false Action by the Deputy Executive Director for Information Services and Administration and Chief Information Officer. 10.33 Section 10.33 Energy NUCLEAR REGULATORY... SECURITY INFORMATION OR AN EMPLOYMENT CLEARANCE Procedures § 10.33 Action by the Deputy Executive Director...

75 FR 31450 - Memorandum of Understanding by and Between the United States Food and Drug Administration and the...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-03

... Administration and the International Anesthesia Research Society for the Safety of Key Inhaled and Intravenous Drugs in Pediatrics Public-Private Partnership AGENCY: Food and Drug Administration, HHS. ACTION: Notice... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2010-N-0004...

Attitudes of Faculty and Administrators Toward Affirmative Action in Higher Education; A Second Look.

ERIC Educational Resources Information Center

Maca, Suanne D.

This dissertation investigated six indications of change regarding affirmative action efforts on the University of Texas at Austin campus since December, 1973. These indications of change were recorded in university personnel documents, EEO/AA Office records, and the results of a questionnaire submitted to the faculty and administrators of the…

12 CFR 513.6 - Duty to file information concerning adverse judicial or administrative action.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Duty to file information concerning adverse judicial or administrative action. 513.6 Section 513.6 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY PRACTICE BEFORE THE OFFICE § 513.6 Duty to file information concerning adverse...

Outstanding School Administrators: Their Keys to Success.

ERIC Educational Resources Information Center

Wendel, Frederick C.; And Others

Project Success was initiated to identify the good things that happen in American public education. One thousand administrators nationwide, identified by their peers as successful were asked to describe their leadership characteristics and beliefs about education. Responses were received from 491 administrators. Chapter 1 presents sample…

Experiences in methods to involve key players in planning protective actions in the case of a nuclear accident.

PubMed

Sinkko, K; Hämäläinen, R P; Hänninen, R

2004-01-01

A widely used method in the planning of protective actions is to establish a stakeholder network to generate a comprehensive set of generic protective actions. The aim is to increase competence and build links for communication and coordination. The approach of this work was to systematically evaluate protective action strategies in the case of a nuclear accident. This was done in a way that the concerns and issues of all key players could be transparently and equally included in the decision taken. An approach called Facilitated Decision Analysis Workshop has been developed and tested. The work builds on case studies in which it was assumed that a hypothetical accident had led to a release of considerable amounts of radionuclides and, therefore, various types of countermeasures had to be considered. Six workshops were organised in the Nordic countries where the key players were represented, i.e. authorities, expert organisations, industry and agricultural producers. Copyright 2004 Oxford University Press

Evaluation of key events in the mode of action for a carry-over carcinogen in mice

EPA Science Inventory

Evaluation of key events in the mode of action for a carry-over carcinogen in mice Charles E. Wood, April D. Lake, Greg Olson, Michael H. George, Susan D. Hester, Anthony B. DeAngelo Introduction: Early life environmental exposures are established determinants for adverse health...

Lipoxins and novel 15-epi-lipoxin analogs display potent anti-inflammatory actions after oral administration.

PubMed

Bannenberg, Gerard; Moussignac, Rose-Laure; Gronert, Karsten; Devchand, Pallavi R; Schmidt, Birgitta A; Guilford, William J; Bauman, John G; Subramanyam, Babu; Perez, H Daniel; Parkinson, John F; Serhan, Charles N

2004-09-01

1. Lipoxins (LX) and aspirin-triggered 15-epi-lipoxins (ATL) exert potent anti-inflammatory actions. In the present study, we determined the anti-inflammatory efficacy of endogenous LXA(4) and LXB(4), the stable ATL analog ATLa2, and a series of novel 3-oxa-ATL analogs (ZK-996, ZK-990, ZK-994, and ZK-142) after intravenous, oral, and topical administration in mice. 2. LXA(4), LXB(4), ATLa2, and ZK-994 were orally active, exhibiting potent systemic inhibition of zymosan A-induced peritonitis at very low doses (50 ng kg(-1)-50 microg kg(-1)). 3. Intravenous ZK-994 and ZK-142 (500 microg kg(-1)) potently attenuated hind limb ischemia/reperfusion-induced lung injury, with 32+/-12 and 53+/-5% inhibition (P<0.05), respectively, of neutrophil accumulation in lungs. The same dose of ATLa2 had no significant protective action. 4. Topical application of ATLa2, ZK-994, and ZK-142 ( approximately 20 microg cm(-2)) prevented vascular leakage and neutrophil infiltration in LTB(4)/PGE(2)-stimulated ear skin inflammation. While ATLa2 and ZK-142 displayed approximately equal anti-inflammatory efficacy in this model, ZK-994 displayed a slower onset of action. 5. In summary, native LXA(4) and LXB(4), and analogs ATLa2, ZK-142, and ZK-994 retain broad anti-inflammatory effects after intravenous, oral, and topical administration. The 3-oxa-ATL analogs, which have enhanced metabolic and chemical stability and a superior pharmacokinetic profile, provide new opportunities to explore the actions and therapeutic potential for LX and ATL.

Ares Knowledge Capture: Summary and Key Themes Presentation

NASA Technical Reports Server (NTRS)

Coates, Ralph H.

2011-01-01

This report has been developed by the National Aeronautics and Space Administration (NASA) Human Exploration and Operations Mission Directorate (HEOMD) Risk Management team in close coordination with the MSFC Chief Engineers Office. This document provides a point-in-time, cumulative, summary of actionable key lessons learned derived from the design project. Lessons learned invariably address challenges and risks and the way in which these areas have been addressed. Accordingly the risk management thread is woven throughout the document.

Function key and shortcut key use in airway facilities.

DOT National Transportation Integrated Search

2003-02-01

This document provides information on the function keys and shortcut keys used by systems in the Federal Aviation Administration : Airway Facilities (AF) work environment. It includes a catalog of the function keys and shortcut keys used by each syst...

ER Stress-Mediated Signaling: Action Potential and Ca(2+) as Key Players.

PubMed

Bahar, Entaz; Kim, Hyongsuk; Yoon, Hyonok

2016-09-15

The proper functioning of the endoplasmic reticulum (ER) is crucial for multiple cellular activities and survival. Disturbances in the normal ER functions lead to the accumulation and aggregation of unfolded proteins, which initiates an adaptive response, the unfolded protein response (UPR), in order to regain normal ER functions. Failure to activate the adaptive response initiates the process of programmed cell death or apoptosis. Apoptosis plays an important role in cell elimination, which is essential for embryogenesis, development, and tissue homeostasis. Impaired apoptosis can lead to the development of various pathological conditions, such as neurodegenerative and autoimmune diseases, cancer, or acquired immune deficiency syndrome (AIDS). Calcium (Ca(2+)) is one of the key regulators of cell survival and it can induce ER stress-mediated apoptosis in response to various conditions. Ca(2+) regulates cell death both at the early and late stages of apoptosis. Severe Ca(2+) dysregulation can promote cell death through apoptosis. Action potential, an electrical signal transmitted along the neurons and muscle fibers, is important for conveying information to, from, and within the brain. Upon the initiation of the action potential, increased levels of cytosolic Ca(2+) (depolarization) lead to the activation of the ER stress response involved in the initiation of apoptosis. In this review, we discuss the involvement of Ca(2+) and action potential in ER stress-mediated apoptosis.

42 CFR 93.405 - Notifying the respondent of findings of research misconduct and HHS administrative actions.

Code of Federal Regulations, 2014 CFR

2014-10-01

... misconduct and HHS administrative actions. 93.405 Section 93.405 Public Health PUBLIC HEALTH SERVICE... RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Responsibilities of the U.S. Department of Health and Human Services Research Misconduct Issues § 93.405 Notifying the respondent of...

42 CFR 93.405 - Notifying the respondent of findings of research misconduct and HHS administrative actions.

Code of Federal Regulations, 2013 CFR

2013-10-01

... misconduct and HHS administrative actions. 93.405 Section 93.405 Public Health PUBLIC HEALTH SERVICE... RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Responsibilities of the U.S. Department of Health and Human Services Research Misconduct Issues § 93.405 Notifying the respondent of...

42 CFR 93.405 - Notifying the respondent of findings of research misconduct and HHS administrative actions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... misconduct and HHS administrative actions. 93.405 Section 93.405 Public Health PUBLIC HEALTH SERVICE... RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Responsibilities of the U.S. Department of Health and Human Services Research Misconduct Issues § 93.405 Notifying the respondent of...

42 CFR 93.405 - Notifying the respondent of findings of research misconduct and HHS administrative actions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... misconduct and HHS administrative actions. 93.405 Section 93.405 Public Health PUBLIC HEALTH SERVICE... RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Responsibilities of the U.S. Department of Health and Human Services Research Misconduct Issues § 93.405 Notifying the respondent of...

42 CFR 93.405 - Notifying the respondent of findings of research misconduct and HHS administrative actions.

Code of Federal Regulations, 2012 CFR

2012-10-01

... misconduct and HHS administrative actions. 93.405 Section 93.405 Public Health PUBLIC HEALTH SERVICE... RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Responsibilities of the U.S. Department of Health and Human Services Research Misconduct Issues § 93.405 Notifying the respondent of...

20 CFR 422.445 - May we bring a civil action against your employer for failure to comply with our administrative...

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false May we bring a civil action against your employer for failure to comply with our administrative wage garnishment order? 422.445 Section 422.445 Employees' Benefits SOCIAL SECURITY ADMINISTRATION ORGANIZATION AND PROCEDURES Collection of Debts by...

Five Key Leadership Actions Needed to Redesign Family Medicine Residencies.

PubMed

Kozakowski, Stanley M; Eiff, M Patrice; Green, Larry A; Pugno, Perry A; Waller, Elaine; Jones, Samuel M; Fetter, Gerald; Carney, Patricia A

2015-06-01

New skills are needed to properly prepare the next generation of physicians and health professionals to practice in medical homes. Transforming residency training to address these new skills requires strong leadership. We sought to increase the understanding of leadership skills useful in residency programs that plan to undertake meaningful change. The Preparing the Personal Physician for Practice (P4) project (2007-2014) was a comparative case study of 14 family medicine residencies that engaged in innovative training redesign, including altering the scope, content, sequence, length, and location of training to align resident education with requirements of the patient-centered medical home. In 2012, each P4 residency team submitted a final summary report of innovations implemented, overall insights, and dissemination activities during the study. Six investigators conducted independent narrative analyses of these reports. A consensus meeting held in September 2012 was used to identify key leadership actions associated with successful educational redesign. Five leadership actions were associated with successful implementation of innovations and residency transformation: (1) manage change; (2) develop financial acumen; (3) adapt best evidence educational strategies to the local environment; (4) create and sustain a vision that engages stakeholders; and (5) demonstrate courage and resilience. Residency programs are expected to change to better prepare their graduates for a changing delivery system. Insights about effective leadership skills can provide guidance for faculty to develop the skills needed to face practical realities while guiding transformation.

Leading School-Wide Improvement in Low-Performing Schools Facing Conditions of Accountability: Key Actions and Considerations

ERIC Educational Resources Information Center

Cosner, Shelby; Jones, Mary F.

2016-01-01

Purpose: The purpose of this paper is to advance a framework that identifies three key domains of work and a set of more nuanced considerations and actions within each domain for school leaders seeking to improve school-wide student learning in low-performing schools facing conditions of accountability. Design/methodology/approach: Review of…

Taking Action: Ideas To Promote Technology Integration [and] Administrator's Desk Reference: Readings To Promote Technology Integration. Technology Integration: A Thematic Focus.

ERIC Educational Resources Information Center

Thormann, Joan, Ed.; And Others

This guide for school administrators interested in technology integration in the curriculum was developed from discussions at the Technology Integration Seminar held in March, 1991. The guide is divided into five chapters covering various administrative responsibilities and action steps. The first chapter presents an overview and identifies…

10 CFR 10.33 - Action by the Deputy Executive Director for Information Services and Administration and Chief...

Code of Federal Regulations, 2010 CFR

2010-01-01

... well as the unfavorable information concerning the individual and shall take into account the value of... 10 Energy 1 2010-01-01 2010-01-01 false Action by the Deputy Executive Director for Information Services and Administration and Chief Information Officer. 10.33 Section 10.33 Energy NUCLEAR REGULATORY...

76 FR 48807 - Public Key Infrastructure (PKI) Certificate Action Form

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-09

...) Certificate Action Form ACTION: Proposed collection; comment request. SUMMARY: The United States Patent and... Certificate Action Form (PTO-2042), which is used by the public to request a new digital certificate, the... applicant. The Certificate Action Form has an accompanying subscriber agreement to ensure that customers...

Neuroendocrine androgen action is a key extraovarian mediator in the development of polycystic ovary syndrome.

PubMed

Caldwell, Aimee S L; Edwards, Melissa C; Desai, Reena; Jimenez, Mark; Gilchrist, Robert B; Handelsman, David J; Walters, Kirsty A

2017-04-18

Polycystic ovary syndrome (PCOS) is a complex hormonal disorder characterized by reproductive, endocrine, and metabolic abnormalities. As the origins of PCOS remain unknown, mechanism-based treatments are not feasible and current management relies on treatment of symptoms. Hyperandrogenism is the most consistent PCOS characteristic; however, it is unclear whether androgen excess, which is treatable, is a cause or a consequence of PCOS. As androgens mediate their actions via the androgen receptor (AR), we combined a mouse model of dihydrotestosterone (DHT)-induced PCOS with global and cell-specific AR-resistant (ARKO) mice to investigate the locus of androgen actions that mediate the development of the PCOS phenotype. Global loss of the AR reveals that AR signaling is required for all DHT-induced features of PCOS. Neuron-specific AR signaling was required for the development of dysfunctional ovulation, classic polycystic ovaries, reduced large antral follicle health, and several metabolic traits including obesity and dyslipidemia. In addition, ovariectomized ARKO hosts with wild-type ovary transplants displayed normal estrous cycles and corpora lutea, despite DHT treatment, implying extraovarian and not intraovarian AR actions are key loci of androgen action in generating the PCOS phenotype. These findings provide strong evidence that neuroendocrine genomic AR signaling is an important extraovarian mediator in the development of PCOS traits. Thus, targeting AR-driven mechanisms that initiate PCOS is a promising strategy for the development of novel treatments for PCOS.

The Importance of Protesters' Morals: Moral Obligation as a Key Variable to Understand Collective Action.

PubMed

Sabucedo, José-Manuel; Dono, Marcos; Alzate, Mónica; Seoane, Gloria

2018-01-01

Collective action and protest have become a normalized political behavior that in many cases defines the political agenda. The reasons why people take to the streets constitute a central subject within the study of social psychology. In the literature, three precedents of protest that have been established as central to the study of this phenomenon are: injustice, efficacy, and identity. But political action is also deeply related to moral values. This explains why in recent years some moral constructs have also been pointed out as predictors of collective action. Moral variables have been introduced into the literature with little consideration to how they relate to each other. Thus, work in this direction is needed. The general aim of this research is to differentiate moral obligation from moral norms and moral conviction, as well as to compare their ability to predict collective action. In order to do so, the research objectives are: (a) conceptualize and operationalize moral obligation (Study 1, N = 171); (b) test its predictive power for intention to participate in protests (Study 2, N = 622); and (c) test moral obligation in a real context (Study 3, N = 407). Results are encouraging, showing not only that moral obligation is different to moral conviction and moral norm, but also that it is a more effective predictor working both for intention and real participation. This work therefore presents moral obligation as a key precedent of protest participation, prompting its future use as a variable that can enhance existing predictive models of collective action. Results regarding other variables are also discussed.

The Importance of Protesters’ Morals: Moral Obligation as a Key Variable to Understand Collective Action

PubMed Central

Sabucedo, José-Manuel; Dono, Marcos; Alzate, Mónica; Seoane, Gloria

2018-01-01

Collective action and protest have become a normalized political behavior that in many cases defines the political agenda. The reasons why people take to the streets constitute a central subject within the study of social psychology. In the literature, three precedents of protest that have been established as central to the study of this phenomenon are: injustice, efficacy, and identity. But political action is also deeply related to moral values. This explains why in recent years some moral constructs have also been pointed out as predictors of collective action. Moral variables have been introduced into the literature with little consideration to how they relate to each other. Thus, work in this direction is needed. The general aim of this research is to differentiate moral obligation from moral norms and moral conviction, as well as to compare their ability to predict collective action. In order to do so, the research objectives are: (a) conceptualize and operationalize moral obligation (Study 1, N = 171); (b) test its predictive power for intention to participate in protests (Study 2, N = 622); and (c) test moral obligation in a real context (Study 3, N = 407). Results are encouraging, showing not only that moral obligation is different to moral conviction and moral norm, but also that it is a more effective predictor working both for intention and real participation. This work therefore presents moral obligation as a key precedent of protest participation, prompting its future use as a variable that can enhance existing predictive models of collective action. Results regarding other variables are also discussed. PMID:29636720

15 CFR 922.50 - Appeals of administrative action.

Code of Federal Regulations, 2010 CFR

2010-01-01

... (Continued) NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE OCEAN AND COASTAL... Administrator for Ocean Services and Coastal Zone Management, NOAA 1305 East-West Highway, 13th Floor, Silver Spring, MD 20910. (c)(1) The Assistant Administrator may request the appellant to submit such information...

15 CFR 922.50 - Appeals of administrative action.

Code of Federal Regulations, 2011 CFR

2011-01-01

... (Continued) NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE OCEAN AND COASTAL... Administrator for Ocean Services and Coastal Zone Management, NOAA 1305 East-West Highway, 13th Floor, Silver Spring, MD 20910. (c)(1) The Assistant Administrator may request the appellant to submit such information...

The Practical Integration of Action Research into Building Climate Literacy and Partnership with Key Influentials

NASA Astrophysics Data System (ADS)

Estrada, M.

2015-12-01

Climate Education Partners (CEP) has been using an action research approach to build climate literacy and partnership with key influential (KI) leaders in the San Diego community. After identifying 6 key sectors that either (a) could reduce green house gas emissions and adapt to impacts, or (b) would be highly vulnerable to the impacts of climate change, we conducted 89 interviews with KIs from the San Diego region -- including elected officials, academics, laborers, and representatives from local businesses, non-profits, ethnic and cultural communities, faith-based groups, and special interest groups -- to assess their science knowledge and opinions about climate change and the impacts of climate change. Other questions asked were about KIs' personal efficacy, identity, values and engagement in pro-environmental behaviors related to climate change. The results of the interviews contributed to CEP's action research approach in two ways: 1) it provided critical data regarding which leaders wanted further engagement with CEP and what that engagement should entail (e.g., being a connector to other leaders, a spokesperson, or a participant in future educational activities), and 2) it provided key information about the extent to which "knowledge deficit" is related to use of climate change knowledge to inform engagement in mitigation and adaptive behaviors. Practically, the results were used to create a database that is being used to inform the contact and education of KIs. We were able to show, consistent with previous research and identity theory, that liberal leaders were more likely than conservatives to believe in, feel concern for, and be knowledgeable about climate change. However, engagement in mitigation behaviors- specifically making decisions that would reduce electricity, gas, or water use- were similar for both groups. These results are being used to create resources and direct climate education activities going forward.

Action Research to Improve Phonological Recognition at Key Stage 1 with Reference to Pupils with Special Educational Needs

ERIC Educational Resources Information Center

Clark, Charlotte

2017-01-01

Given the focus on phonological attainment in the National Phonics Screening Check, small-scale school-based action research was undertaken to improve phonological recognition and assess the impact on progress and attainment in a sample drawn from Key Stage 1 which included pupils on the Special Educational Needs (SEN) Register. The research…

Work Keys USA.

ERIC Educational Resources Information Center

Work Keys USA, 1998

1998-01-01

"Work Keys" is a comprehensive program for assessing and teaching workplace skills. This serial "special issue" features 18 first-hand reports on Work Keys projects in action in states across North America. They show how the Work Keys is helping businesses and educators solve the challenge of building a world-class work force.…

Conqueror and Administrator: Civil and Military Actions of Marshall Louis-Gabriel Suchet in the Spanish Province of Aragon, 1808-1813

DTIC Science & Technology

2008-05-01

action as an administrator was to prevent the displacement to Madrid of the silver objects of worship from the Church of Notre Dame du Pilar in Saragossa...respect for the Catholic Church , and their aversion for the central power in Madrid . This apparently benevolent action was indeed a skilful information...Insurgencies and Counter-Insurgencies: Guerillas and their Opponents since 1750.London and New York: Routledge, 2001. • Bell , David A. The First Total War.Boston

Neuroendocrine androgen action is a key extraovarian mediator in the development of polycystic ovary syndrome

PubMed Central

Caldwell, Aimee S. L.; Edwards, Melissa C.; Desai, Reena; Jimenez, Mark; Gilchrist, Robert B.; Walters, Kirsty A.

2017-01-01

Polycystic ovary syndrome (PCOS) is a complex hormonal disorder characterized by reproductive, endocrine, and metabolic abnormalities. As the origins of PCOS remain unknown, mechanism-based treatments are not feasible and current management relies on treatment of symptoms. Hyperandrogenism is the most consistent PCOS characteristic; however, it is unclear whether androgen excess, which is treatable, is a cause or a consequence of PCOS. As androgens mediate their actions via the androgen receptor (AR), we combined a mouse model of dihydrotestosterone (DHT)-induced PCOS with global and cell-specific AR-resistant (ARKO) mice to investigate the locus of androgen actions that mediate the development of the PCOS phenotype. Global loss of the AR reveals that AR signaling is required for all DHT-induced features of PCOS. Neuron-specific AR signaling was required for the development of dysfunctional ovulation, classic polycystic ovaries, reduced large antral follicle health, and several metabolic traits including obesity and dyslipidemia. In addition, ovariectomized ARKO hosts with wild-type ovary transplants displayed normal estrous cycles and corpora lutea, despite DHT treatment, implying extraovarian and not intraovarian AR actions are key loci of androgen action in generating the PCOS phenotype. These findings provide strong evidence that neuroendocrine genomic AR signaling is an important extraovarian mediator in the development of PCOS traits. Thus, targeting AR-driven mechanisms that initiate PCOS is a promising strategy for the development of novel treatments for PCOS. PMID:28320971

Noribogaine, but not 18-MC, exhibits similar actions as ibogaine on GDNF expression and ethanol self-administration

PubMed Central

Carnicella, Sebastien; He, Dao-Yao; Yowell, Quinn V.; Glick, Stanley D.; Ron, Dorit

2013-01-01

Ibogaine is a naturally occurring alkaloid that has been reported to decrease various adverse phenotypes associated with exposure to drugs of abuse and alcohol in human and rodent models. Unfortunately, ibogaine cannot be used as a medication to treat addiction because of severe side effects. Previously, we reported that the desirable actions of ibogaine to reduce self-administration of, and relapse to, alcohol consumption are mediated via the upregulation of the expression of the glial cell line-derived neurotrophic factor (GDNF) in the midbrain ventral tegmental area (VTA), and the consequent activation of the GDNF pathway. The ibogaine metabolite, noribogaine, and a synthetic derivative of ibogaine, 18-Methoxycoronaridine (18-MC), possess a similar anti-addictive profile as ibogaine in rodent models, but without some of its adverse side effects. Here, we determined whether noribogaine and/or 18-MC, like ibogaine, increase GDNF expression, and whether their site of action to reduce alcohol consumption is the VTA. We used SH-SY5Y cells as a cell culture model and found that noribogaine, like ibogaine, but not 18-MC, induces a robust increase in GDNF mRNA levels. Next, we tested the effect of intra-VTA infusion of noribogaine and 18-MC on rat operant alcohol self-administration and found that noribogaine, but not 18-MC, in the VTA decreases responding for alcohol. Together, our results suggest that noribogaine and 18-MC have different mechanisms and sites of action. PMID:21040239

We Need Action on Social Determinants of Health - but Do We Want It, too? Comment on "Understanding the Role of Public Administration in Implementing Action on the Social Determinants of Health and Health Inequities".

PubMed

de Leeuw, Evelyne

2016-02-27

Recently a number of calls have been made to mobilise the arsenal of political science insights to investigate - and point to improvements in - the social determinants of health (SDH), and health equity. Recently, in this journal, such a rallying appeal was made for the field of public administration. This commentary argues that, although scholarly potential should justifiably be redirected to resolve these critical issues for humanity, a key ingredient in taking action may have been neglected. This factor is 'community.' Community health has been a standard element of the public health and health promotion, even political, repertoire for decades now. But this commentary claims that communities are insufficiently charged, equipped or appreciated to play the role that scholarship attributes (or occasionally avoids to identify) to them. Community is too important to not fully engage and understand. Rhetorical tools and inquiries can support their quintessential role. © 2016 by Kerman University of Medical Sciences.

Effective School-Community Relations as a Key Performance Indicator for the Secondary School Administrator in Aba South District, Nigeria

ERIC Educational Resources Information Center

Abraham, Nath. M.; Ememe, Ogbonna N.

2012-01-01

This study investigates Effective School-Community Relations as a key Performance Indicator (KPI) of Secondary Schools Administrator in Aba South District, Nigeria. Descriptive survey method was adopted. All the 248 teachers made up the population and sample in a purposive sampling technique representing 100% of the entire population as sample. A…

5 CFR 1201.125 - Administrative law judge.

Code of Federal Regulations, 2010 CFR

2010-01-01

... PRACTICES AND PROCEDURES Procedures for Original Jurisdiction Cases Special Counsel Disciplinary Actions § 1201.125 Administrative law judge. (a) An administrative law judge will hear a disciplinary action... complaint seeking disciplinary action against a Federal or District of Columbia government employee for a...

7 CFR 356.4 - Property valued at $10,000 or less; notice of seizure administrative action to obtain forfeiture.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 5 2012-01-01 2012-01-01 false Property valued at $10,000 or less; notice of seizure administrative action to obtain forfeiture. 356.4 Section 356.4 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE FORFEITURE...

78 FR 43091 - Technical Operations Safety Action Program (T-SAP) and Air Traffic Safety Action Program (ATSAP)

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-19

... Administration 14 CFR Part 193 [Docket No.: FAA-2013-0375] Technical Operations Safety Action Program (T-SAP) and Air Traffic Safety Action Program (ATSAP) AGENCY: Federal Aviation Administration (FAA), Department of Transportation (DOT). ACTION: Notice of Proposed Order Designating Safety Information as Protected from...

Noribogaine, but not 18-MC, exhibits similar actions as ibogaine on GDNF expression and ethanol self-administration.

PubMed

Carnicella, Sebastien; He, Dao-Yao; Yowell, Quinn V; Glick, Stanley D; Ron, Dorit

2010-10-01

Ibogaine is a naturally occurring alkaloid that has been reported to decrease various adverse phenotypes associated with exposure to drugs of abuse and alcohol in human and rodent models. Unfortunately, ibogaine cannot be used as a medication to treat addiction because of severe side effects. Previously, we reported that the desirable actions of ibogaine to reduce self-administration of, and relapse to, alcohol consumption are mediated via the upregulation of the expression of the glial cell line-derived neurotrophic factor (GDNF) in the midbrain ventral tegmental area (VTA), and the consequent activation of the GDNF pathway. The ibogaine metabolite, noribogaine, and a synthetic derivative of ibogaine, 18-Methoxycoronaridine (18-MC), possess a similar anti-addictive profile as ibogaine in rodent models, but without some of its adverse side effects. Here, we determined whether noribogaine and/or 18-MC, like ibogaine, increase GDNF expression, and whether their site of action to reduce alcohol consumption is the VTA. We used SH-SY5Y cells as a cell culture model and found that noribogaine, like ibogaine, but not 18-MC, induces a robust increase in GDNF mRNA levels. Next, we tested the effect of intra-VTA infusion of noribogaine and 18-MC on rat operant alcohol self-administration and found that noribogaine, but not 18-MC, in the VTA decreases responding for alcohol. Together, our results suggest that noribogaine and 18-MC have different mechanisms and sites of action. © 2010 The Authors, Addiction Biology © 2010 Society for the Study of Addiction.

5 CFR 532.413 - Simultaneous action.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Simultaneous action. 532.413 Section 532.413 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PREVAILING RATE SYSTEMS Pay Administration § 532.413 Simultaneous action. (a) If an employee becomes entitled to more than...

46 CFR 327.8 - Court action.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 8 2010-10-01 2010-10-01 false Court action. 327.8 Section 327.8 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION A-NATIONAL SHIPPING AUTHORITY SEAMEN'S CLAIMS; ADMINISTRATIVE ACTION AND LITIGATION § 327.8 Court action. No seamen, having a claim specified in subsections (2) and (3) of...

46 CFR 327.8 - Court action.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 8 2011-10-01 2011-10-01 false Court action. 327.8 Section 327.8 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION A-NATIONAL SHIPPING AUTHORITY SEAMEN'S CLAIMS; ADMINISTRATIVE ACTION AND LITIGATION § 327.8 Court action. No seamen, having a claim specified in subsections (2) and (3) of...

45 CFR 77.4 - Remedial actions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 45 Public Welfare 1 2011-10-01 2011-10-01 false Remedial actions. 77.4 Section 77.4 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION REMEDIAL ACTIONS APPLICABLE TO LETTER OF CREDIT ADMINISTRATION § 77.4 Remedial actions. If, after the conclusion of the procedures set forth in...

45 CFR 77.4 - Remedial actions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 45 Public Welfare 1 2010-10-01 2010-10-01 false Remedial actions. 77.4 Section 77.4 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION REMEDIAL ACTIONS APPLICABLE TO LETTER OF CREDIT ADMINISTRATION § 77.4 Remedial actions. If, after the conclusion of the procedures set forth in...

14 CFR 1275.106 - Administrative actions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 1275.106 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION RESEARCH MISCONDUCT § 1275... that an institutional official other than those guilty of research misconduct certify the accuracy of... institution to ensure that steps have been taken to prevent repetition of the research misconduct. (3) Group...

14 CFR 1275.106 - Administrative actions.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 1275.106 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION RESEARCH MISCONDUCT § 1275... that an institutional official other than those guilty of research misconduct certify the accuracy of... institution to ensure that steps have been taken to prevent repetition of the research misconduct. (3) Group...

14 CFR 1275.106 - Administrative actions.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 1275.106 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION RESEARCH MISCONDUCT § 1275... that an institutional official other than those guilty of research misconduct certify the accuracy of... institution to ensure that steps have been taken to prevent repetition of the research misconduct. (3) Group...

14 CFR 1275.106 - Administrative actions.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 1275.106 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION RESEARCH MISCONDUCT § 1275... that an institutional official other than those guilty of research misconduct certify the accuracy of... institution to ensure that steps have been taken to prevent repetition of the research misconduct. (3) Group...

29 CFR 15.6 - Administrative action.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Solicitor in a timely manner. The Administrative Report shall be in the form of a single memorandum in narrative form with attachments. It should contain all of the following elements, unless permission is... suit. (d) Litigation. During the course of any litigation, organizational units are responsible for...

77 FR 42360 - Actions on Special Permit Applications

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-18

... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration Actions on... Safety Administration (PHMSA), DOT. ACTION: Notice of actions on Special Permit Applications. SUMMARY: In... given of the actions on special permits applications in (June to June 2012). The mode of transportation...

7 CFR 356.4 - Property valued at $10,000 or less; notice of seizure administrative action to obtain forfeiture.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false Property valued at $10,000 or less; notice of seizure... PROCEDURES § 356.4 Property valued at $10,000 or less; notice of seizure administrative action to obtain... notice of seizure and proposed forfeiture as provided in paragraph (c)(1) of this section, by posting for...

From Headline to Hard Grind: The Importance of Understanding Public Administration in Achieving Health Outcomes

PubMed Central

O’Flynn, Janine

2016-01-01

Many public policy programs fail to translate ambitious headlines to on-the-ground action. The reasons for this are many and varied, but for public administration and management scholars a large part of the gap between ambition and achievement is the challenge associated with the operation of the machinery of government itself, and how it relates to the other parties that it relies on to fulfill these outcomes. In their article, Carey and Friel set out key reasons why public health scholars should seek to better understand important ideas in public administration. In commenting on their contribution, I draw out two critical questions that are raised by this discussion: (i) what are boundaries and what forms do they take? and (ii) why work across boundaries? Expanding on these key questions extends the points made by Carey and Friel on the importance of understanding public administration and will better place public health scholars and practitioners to realise health outcomes. PMID:27694672

78 FR 9771 - Federal Highway Administration

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-11

... DEPARTMENT OF TRANSPORTATION Federal Highway Administration Notice of Final Federal Agency Action on Proposed Transportation Project in Illinois and Indiana AGENCY: Federal Highway Administration...., Acting Division Administrator, Federal Highway Administration, 3250 Executive Park Drive, Springfield...

Teaching Public Administration: Key Themes 1996-2016

ERIC Educational Resources Information Center

Fenwick, John

2018-01-01

In this article, the aim is to explore some of the key themes to emerge in the journal during the past two decades. Each selected theme will be reviewed in the light of issues raised in particular papers. The aim of this approach is, first, to facilitate reflection upon the contribution of the journal as its subject matter has moved from a concern…

Psychologists in Academic Administration: A Call to Action and Service.

PubMed

Schmaling, Karen B; Linton, John C

2017-06-01

Academic psychologists' backgrounds may prepare them for many aspects of academic administration such as: understanding and working with people; prioritizing others' needs and institutional needs; and managing projects and budgets, e.g., for research grants or training programs. Contemporary academic health centers also may provide opportunities for psychologists to serve in academic health administration. This article encourages psychologists to consider preparing for and seeking administrative and higher-level leadership roles. Six psychologists serving diverse administrative roles-from vice chairs in medical school departments to presidents of universities with academic health centers-reflected on: their paths to administration; their preparation for administrative roles; and the commonalities and differences between the work and skills sets of psychologist health service providers and the work and skill sets required for higher level administrative and leadership roles.

45 CFR 77.5 - Remedial action procedures.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 45 Public Welfare 1 2010-10-01 2010-10-01 false Remedial action procedures. 77.5 Section 77.5 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION REMEDIAL ACTIONS APPLICABLE TO LETTER OF CREDIT ADMINISTRATION § 77.5 Remedial action procedures. Except as provided in § 77.6...

Ameliorating treatment-refractory depression with intranasal ketamine: potential NMDA receptor actions in the pain circuitry representing mental anguish.

PubMed

Opler, Lewis A; Opler, Mark G A; Arnsten, Amy F T

2016-02-01

This article reviews the antidepressant actions of ketamine, an N-methyl-D-aspartame glutamate receptor (NMDAR) antagonist, and offers a potential neural mechanism for intranasal ketamine's ultra-rapid actions based on the key role of NMDAR in the nonhuman primate prefrontal cortex (PFC). Although intravenous ketamine infusions can lift mood within hours, the current review describes how intranasal ketamine administration can have ultra-rapid antidepressant effects, beginning within minutes (5-40 minutes) and lasting hours, but with repeated treatments needed for sustained antidepressant actions. Research in rodents suggests that increased synaptogenesis in PFC may contribute to the prolonged benefit of ketamine administration, beginning hours after administration. However, these data cannot explain the relief that occurs within minutes of intranasal ketamine delivery. We hypothesize that the ultra-rapid effects of intranasal administration in humans may be due to ketamine blocking the NMDAR circuits that generate the emotional representations of pain (eg, Brodmann Areas 24 and 25, insular cortex), cortical areas that can be overactive in depression and which sit above the nasal epithelium. In contrast, NMDAR blockade in the dorsolateral PFC following systemic administration of ketamine may contribute to cognitive deficits. This novel view may help to explain how intravenous ketamine can treat the symptoms of depression yet worsen the symptoms of schizophrenia.

76 FR 34120 - Action Subject to Intergovernmental Review

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-10

... SMALL BUSINESS ADMINISTRATION Action Subject to Intergovernmental Review AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: Under Executive Order 12372, the Small Business Administration (SBA) is notifying the public that it intends to grant the pending applications of 39 existing...

76 FR 34119 - Action Subject to Intergovernmental Review

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-10

... SMALL BUSINESS ADMINISTRATION Action Subject to Intergovernmental Review AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: Under Executive Order 12372, the Small Business Administration (SBA) is notifying the public that it intends to grant the pending applications of 22 existing...

Transcriptomic dose-and-time-course indicators of early key events in a cytotoxicity-mediated mode of action for rodent urinary bladder tumorigenesis

EPA Science Inventory

TRANSCRIPTOMIC DOSE- AND TIME-COURSE INDICATORS OF EARLY KEY EVENTS IN A CYTOTOXICITY-MEDIATED MODE OF ACTION FOR RODENT URINARY BLADDER TUMORIGENESISDiuron is a substituted urea compound used globally as an herbicide. Urinary bladder tumors were induced in rats after chronic die...

48 CFR 342.7101 - Contract administration.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 4 2013-10-01 2013-10-01 false Contract administration. 342.7101 Section 342.7101 Federal Acquisition Regulations System HEALTH AND HUMAN SERVICES CONTRACT MANAGEMENT CONTRACT ADMINISTRATION Administrative Actions for Cost Overruns 342.7101 Contract administration. ...

48 CFR 342.7101 - Contract administration.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 4 2011-10-01 2011-10-01 false Contract administration. 342.7101 Section 342.7101 Federal Acquisition Regulations System HEALTH AND HUMAN SERVICES CONTRACT MANAGEMENT CONTRACT ADMINISTRATION Administrative Actions for Cost Overruns 342.7101 Contract administration. ...

28 CFR 544.44 - Disciplinary action.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Disciplinary action. 544.44 Section 544.44 Judicial Administration BUREAU OF PRISONS, DEPARTMENT OF JUSTICE INSTITUTIONAL MANAGEMENT EDUCATION Mandatory English-as-a-Second Language Program (ESL) § 544.44 Disciplinary action. As with any...

28 CFR 544.44 - Disciplinary action.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 28 Judicial Administration 2 2011-07-01 2011-07-01 false Disciplinary action. 544.44 Section 544.44 Judicial Administration BUREAU OF PRISONS, DEPARTMENT OF JUSTICE INSTITUTIONAL MANAGEMENT EDUCATION Mandatory English-as-a-Second Language Program (ESL) § 544.44 Disciplinary action. As with any...

28 CFR 544.75 - Disciplinary action.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 28 Judicial Administration 2 2011-07-01 2011-07-01 false Disciplinary action. 544.75 Section 544.75 Judicial Administration BUREAU OF PRISONS, DEPARTMENT OF JUSTICE INSTITUTIONAL MANAGEMENT EDUCATION Literacy Program § 544.75 Disciplinary action. As with other mandatory programs, such as work...

Balancing RIF & Affirmative Action: A Guidebook for Administrators. Draft.

ERIC Educational Resources Information Center

Ruzicka, Pat; Berard, Barbara, Ed.

The result of two seminars bringing together educators to discuss the "often conflicting requirements of affirmative action and reductions in force" (RIF), this booklet is intended to provide practical insights and suggestions on meeting affirmative action goals "in situations characterized by staff and program cutbacks." Chapter 1 describes…

Five key recommendations for the implementation of Hospital Electronic Prescribing and Medicines Administration systems in Scotland.

PubMed

Cresswell, Kathrin; Slee, Ann; Sheikh, Aziz

2017-01-24

NHS Scotland is about to embark on the implementation of Hospital Electronic Prescribing and Medicines Administration (HEPMA) systems. There are a number of risks associated with such ventures, thus drawing on existing experiences from other settings is crucial in informing deployment.Drawing on our previous and ongoing work in English settings as well as the international literature, we reflect on key lessons that NHS Scotland may wish to consider in going forward. These deliberations include recommendations surrounding key aspects of deployment strategy surrounding: 1) the way central coordination should be conceptualised, 2) how flexibility in can be ensured, 3) paying attention to optimising systems from the outset, 4) how expertise should be developed and centrally shared, and 5) ways in which learning from experience can be maximised.Our five recommendations will, we hope, provide a starting point for the strategic deliberations of policy makers. Throughout this journey, it is important to view the deployment of HEPMA as part of a wider strategic goal of creating integrated digital infrastructures across Scotland.

[Public control and equity of access to hospitals under non-State public administration].

PubMed

Carneiro Junior, Nivaldo; Elias, Paulo Eduardo

2006-10-01

To analyze social health organizations in the light of public control and the guarantee of equity of access to health services. Utilizing the case study technique, two social health organizations in the metropolitan region of São Paulo were selected. The analytical categories were equity of access and public control, and these were based on interviews with key informants and technical-administrative reports. It was observed that the overall funding and administrative control of the social health organizations are functions of the state administrator. The presence of a local administrator is important for ensuring equity of access. Public control is expressed through supervisory actions, by means of accounting and financial procedures. Equity of access and public control are not taken into consideration in the administration of these organizations. The central question lies in the capacity of the public authorities to have a presence in implementing this model at the local level, thereby ensuring equity of access and taking public control into consideration.

22 CFR 223.11 - Appropriate action.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Appropriate action. 223.11 Section 223.11...-EMPLOYMENT RESTRICTIONS § 223.11 Appropriate action. The Administrator may take appropriate action in the... action. ...

22 CFR 223.11 - Appropriate action.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Appropriate action. 223.11 Section 223.11...-EMPLOYMENT RESTRICTIONS § 223.11 Appropriate action. The Administrator may take appropriate action in the... action. ...

A Plan for Action: Key Perspectives from the Racial/Ethnic Disparities Strategy Forum

PubMed Central

King, Roderick K; Green, Alexander R; Tan-Mcgrory, Aswita; Donahue, Elizabeth J; Kimbrough-Sugick, Jessie; Betancourt, Joseph R

2008-01-01

Context Racial and ethnic disparities in health care in the United States have been well documented, with research largely focusing on describing the problem rather than identifying the best practices or proven strategies to address it. Methods In 2006, the Disparities Solutions Center convened a one-and-a-half-day Strategy Forum composed of twenty experts from the fields of racial/ethnic disparities in health care, quality improvement, implementation research, and organizational excellence, with the goal of deciding on innovative action items and adoption strategies to address disparities. The forum used the Results Based Facilitation model, and several key recommendations emerged. Findings The forum's participants concluded that to identify and effectively address racial/ethnic disparities in health care, health care organizations should: (1) collect race and ethnicity data on patients or enrollees in a routine and standardized fashion; (2) implement tools to measure and monitor for disparities in care; (3) develop quality improvement strategies to address disparities; (4) secure the support of leadership; (5) use incentives to address disparities; and (6) create a messaging and communication strategy for these efforts. This article also discusses these recommendations in the context of both current efforts to address racial and ethnic disparities in health care and barriers to progress. Conclusions The Strategy Forum's participants concluded that health care organizations needed a multifaceted plan of action to address racial and ethnic disparities in health care. Although the ideas offered are not necessarily new, the discussion of their practical development and implementation should make them more useful. PMID:18522613

15 CFR 766.25 - Administrative action denying export privileges.

Code of Federal Regulations, 2013 CFR

2013-01-01

... of a violation of the EAA, the EAR, or any order, license, or authorization issued thereunder; any... transaction subject to the EAR. Before taking action to deny a person export privileges under this section... privileges” for purposes of § 736.2(b)(4) (General Prohibition 4—Engage in actions prohibited by a denial...

15 CFR 766.25 - Administrative action denying export privileges.

Code of Federal Regulations, 2012 CFR

2012-01-01

... of a violation of the EAA, the EAR, or any order, license, or authorization issued thereunder; any... transaction subject to the EAR. Before taking action to deny a person export privileges under this section... privileges” for purposes of § 736.2(b)(4) (General Prohibition 4—Engage in actions prohibited by a denial...

15 CFR 766.25 - Administrative action denying export privileges.

Code of Federal Regulations, 2010 CFR

2010-01-01

... of a violation of the EAA, the EAR, or any order, license, or authorization issued thereunder; any... transaction subject to the EAR. Before taking action to deny a person export privileges under this section... privileges” for purposes of § 736.2(b)(4) (General Prohibition 4—Engage in actions prohibited by a denial...

15 CFR 766.25 - Administrative action denying export privileges.

Code of Federal Regulations, 2011 CFR

2011-01-01

... of a violation of the EAA, the EAR, or any order, license, or authorization issued thereunder; any... transaction subject to the EAR. Before taking action to deny a person export privileges under this section... privileges” for purposes of § 736.2(b)(4) (General Prohibition 4—Engage in actions prohibited by a denial...

15 CFR 766.25 - Administrative action denying export privileges.

Code of Federal Regulations, 2014 CFR

2014-01-01

... of a violation of the EAA, the EAR, or any order, license, or authorization issued thereunder; any... transaction subject to the EAR. Before taking action to deny a person export privileges under this section... privileges” for purposes of § 736.2(b)(4) (General Prohibition 4—Engage in actions prohibited by a denial...

28 CFR 115.404 - Audit corrective action plan.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Audit corrective action plan. 115.404 Section 115.404 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Auditing and Corrective Action § 115.404 Audit corrective action plan. (a) A finding of...

28 CFR 115.404 - Audit corrective action plan.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Audit corrective action plan. 115.404 Section 115.404 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Auditing and Corrective Action § 115.404 Audit corrective action plan. (a) A finding of...

28 CFR 115.404 - Audit corrective action plan.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Audit corrective action plan. 115.404 Section 115.404 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Auditing and Corrective Action § 115.404 Audit corrective action plan. (a) A finding of...

28 CFR 902.7 - Court action.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Court action. 902.7 Section 902.7 Judicial Administration NATIONAL CRIME PREVENTION AND PRIVACY COMPACT COUNCIL DISPUTE ADJUDICATION PROCEDURES § 902.7 Court action. Pursuant to Section (c) of Article XI of the Compact, a decision by the...

Response to Agencywide Crisis: A Model for Administrative Action.

ERIC Educational Resources Information Center

Alwon, Floyd J.

1980-01-01

Guidelines are suggested whereby mental health agency administrators can promote organizational growth and avoid dangers during an agency crisis. Emphasis is placed on the administrator's comprehension of leadership styles and task organization. Typical staff reactions to agency crises are described. (Author/DB)

Practical and Secure Recovery of Disk Encryption Key Using Smart Cards

NASA Astrophysics Data System (ADS)

Omote, Kazumasa; Kato, Kazuhiko

In key-recovery methods using smart cards, a user can recover the disk encryption key in cooperation with the system administrator, even if the user has lost the smart card including the disk encryption key. However, the disk encryption key is known to the system administrator in advance in most key-recovery methods. Hence user's disk data may be read by the system administrator. Furthermore, if the disk encryption key is not known to the system administrator in advance, it is difficult to achieve a key authentication. In this paper, we propose a scheme which enables to recover the disk encryption key when the user's smart card is lost. In our scheme, the disk encryption key is not preserved anywhere and then the system administrator cannot know the key before key-recovery phase. Only someone who has a user's smart card and knows the user's password can decrypt that user's disk data. Furthermore, we measured the processing time required for user authentication in an experimental environment using a virtual machine monitor. As a result, we found that this processing time is short enough to be practical.

50 CFR 11.24 - Final administrative action.

Code of Federal Regulations, 2010 CFR

2010-10-01

... TAKING, POSSESSION, TRANSPORTATION, SALE, PURCHASE, BARTER, EXPORTATION, AND IMPORTATION OF WILDLIFE AND... law judge's decision shall constitute the final administrative determination of the Secretary in the matter and shall become effective 30 calendar days from the date of the decision. ...

Combining administrative data feedback, reflection and action planning to engage primary care professionals in quality improvement: qualitative assessment of short term program outcomes.

PubMed

Vachon, Brigitte; Désorcy, Bruno; Gaboury, Isabelle; Camirand, Michel; Rodrigue, Jean; Quesnel, Louise; Guimond, Claude; Labelle, Martin; Huynh, Ai-Thuy; Grimshaw, Jeremy

2015-09-18

Improving primary care for chronic disease management requires a coherent, integrated approach to quality improvement. Evidence in the continuing professional development (CPD) field suggests the importance of using strategies such as feedback delivery, reflective practice and action planning to facilitate recognition of gaps and service improvement needs. Our study explored the outcomes of a CPD intervention, named the COMPAS Project, which consists of a three-hour workshop composed of three main activities: feedback, critical reflection and action planning. The feedback intervention is delivered face-to-face and presents performance indicators extracted from clinical-administrative databases. This aim of this study was to assess the short term outcomes of this intervention to engage primary care professional in continuous quality improvement (QI). In order to develop an understanding of our intervention and of its short term outcomes, a program evaluation approach was used. Ten COMPAS workshops on diabetes management were directly observed and qualitative data was collected to assess the intervention short term outcomes. Data from both sources were combined to describe the characteristics of action plans developed by professionals. Two independent coders analysed the content of these plans to assess if they promoted engagement in QI and interprofessional collaboration. During the ten workshops held, 26 interprofessional work teams were formed. Twenty-two of them developed a QI project they could implement themselves and that targeted aspects of their own practice they perceived in need of change. Most frequently prioritized strategies for change were improvement of systematic clientele follow-up, medication compliance, care pathway and support to improve adoption of healthier life habits. Twenty-one out of 22 action plans were found to target some level of improvement of interprofessional collaboration in primary care. Our study results demonstrate that the

42 CFR 93.523 - The Administrative Law Judge's ruling.

Code of Federal Regulations, 2010 CFR

2010-10-01

... POLICIES ON RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions Hearing Process § 93.523 The Administrative Law Judge's ruling. (a) The ALJ shall issue a... decision in whole or in part is the final HHS action, unless debarment or suspension is an administrative...

42 CFR 93.523 - The Administrative Law Judge's ruling.

Code of Federal Regulations, 2011 CFR

2011-10-01

... POLICIES ON RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions Hearing Process § 93.523 The Administrative Law Judge's ruling. (a) The ALJ shall issue a... decision in whole or in part is the final HHS action, unless debarment or suspension is an administrative...

75 FR 6433 - Federal Aviation Administration

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-09

... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Notice of Availability of a Draft... 9, West Chicago, IL AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of... Surveillance Radar, Model 9, West Chicago, Illinois. SUMMARY: The Federal Aviation Administration (FAA...

75 FR 18014 - Federal Highway Administration

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-08

... DEPARTMENT OF TRANSPORTATION Federal Highway Administration AGENCY: Federal Highway Administration (FHWA), DOT. ACTION: Notice of Availability regarding a Finding of No Significant Impact (FONSI): U.S.... FOR FURTHER INFORMATION CONTACT: Federal Highway Administration, Kentucky Division: Mr. Greg Rawlings...

76 FR 78966 - Federal Aviation Administration

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-20

... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Approval of Noise Compatibility Program for Kona International Airport at Keahole, Keahole, North Kona, HI AGENCY: Federal Aviation Administration, DOT. ACTION: Notice. SUMMARY: The Federal Aviation Administration (FAA) announces its findings on...

75 FR 12809 - Federal Aviation Administration

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-17

... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Notice of Intent To Rule on Request...: Federal Aviation Administration (FAA), DOT. ACTION: Notice of Request to Release Airport Property. SUMMARY... Nicely, Manager, Federal Aviation Administration, Southwest Region, Airports Division, Texas Airports...

An Administrator's Self-Esteem Is Key to Effective Delegation.

ERIC Educational Resources Information Center

Armenta, Anthony D.; Reno, Thomas R.

1991-01-01

Argues that administrative effectiveness requires delegation; that delegation is a learned skill; and that low self-esteem and weak delegation skills are closely related. Summarizes literature offering warnings and tips about delegation. (DMM)

The gender differences in the inhibitory action of UVB-induced melanocyte activation by the administration of tranexamic acid.

PubMed

Hiramoto, Keiichi; Yamate, Yurika; Sugiyama, Daijiro; Takahashi, Yumi; Mafune, Eiichi

2016-05-01

Tranexamic acid has an inhibitory action on ultraviolet (UV) B-induced melanocyte activation. This study examined the sex differences in the inhibitory action of tranexamic acid on UVB-induced melanocyte activation. We irradiated the eye and ear of male and female mice with UVB at a dose of 1.0 kJ/m(2) using a 20SE sunlamp. We orally administered tranexamic acid (750 mg/kg/day) at 30 min before UVB exposure. Tranexamic acid inhibited the UVB-induced epidermal melanocyte activation, and the effect was more remarkable under UVB eye irradiation than under UVB ear irradiation. Furthermore, the melanocyte activity suppression effect was stronger in female mice than in male mice. Following the administration of tranexamic acid, the female displayed increased blood levels of β-endorphin and μ-opioid receptor and estradiol receptor β expression in comparison with the male. Furthermore, the effect of melanocyte activity suppression in the female mice was decreased by the administration of tamoxifen (antagonist of estrogen receptor) or naltrexone (antagonist of μ-opioid receptor). These results suggest that the suppression by tranexamic acid of the UVB-induced melanocyte activation (UVB sensitivity) is stronger in female mice than in male mice and that female hormones and β-endorphin play an important role in this sex difference. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

78 FR 25524 - Federal Aviation Administration

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-01

... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Notice of Request To Release Airport Property AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of Intent to Rule on Request to... address: Lynn D. Martin, Airports Compliance Specialist, Federal Aviation Administration, Airports...

5 CFR 772.102 - Interim personnel actions.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 5 Administrative Personnel 2 2011-01-01 2011-01-01 false Interim personnel actions. 772.102 Section 772.102 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) INTERIM RELIEF General § 772.102 Interim personnel actions. When an employee or...

5 CFR 772.102 - Interim personnel actions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Interim personnel actions. 772.102 Section 772.102 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) INTERIM RELIEF General § 772.102 Interim personnel actions. When an employee or...

78 FR 13395 - Federal Aviation Administration

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-27

... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Notice of Availability of Draft...: Federal Aviation Administration (FAA), DOT. ACTION: Notice of availability and request for comments... 4. U.S. Mail: Leslie Grey--AAL-614, Federal Aviation Administration, Airports Division, 222 West 7th...

78 FR 41183 - Federal Aviation Administration

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-09

... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Meeting: RTCA Program Management Committee AGENCY: Federal Aviation Administration (FAA), U.S. Department of Transportation (DOT). ACTION... Operations Group, Federal Aviation Administration. [FR Doc. 2013-16464 Filed 7-8-13; 8:45 am] BILLING CODE...

14 CFR § 1275.106 - Administrative actions.

Code of Federal Regulations, 2014 CFR

2014-01-01

... § 1275.106 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION RESEARCH MISCONDUCT... that an institutional official other than those guilty of research misconduct certify the accuracy of... institution to ensure that steps have been taken to prevent repetition of the research misconduct. (3) Group...

AMELIORATING TREATMENT-REFRACTORY DEPRESSION WITH INTRANASAL KETAMINE: POTENTIAL NMDA RECEPTOR ACTIONS IN THE PAIN CIRCUITRY REPRESENTING MENTAL ANGUISH

PubMed Central

Opler, Lewis A.; Opler, Mark G.; Arnsten, Amy F.T.

2014-01-01

This paper reviews the anti-depressant actions of the N-methyl-D-aspartame glutamate receptor (NMDAR) antagonist, ketamine, and offers a potential neural mechanism for intranasal ketamine’s ultra-rapid actions based on the key role of NMDAR in the nonhuman primate prefrontal cortex (PFC). Although intravenous ketamine infusions can lift mood within hours, the current review describes how intranasal ketamine administration can have ultra-rapid antidepressant effects, beginning within minutes (5–40 minutes) and lasting hours, but with repeated treatments needed for sustained antidepressant actions. Research in rodents suggests that increased synaptogenesis in PFC may contribute to the prolonged benefit of ketamine administration, beginning hours after administration. However, these data cannot explain the relief that occurs within minutes of intranasal ketamine delivery. We hypothesize that the ultra-rapid effects of intranasal administration in humans may be due to ketamine blocking the NMDAR circuits that generate the emotional representations of pain (e.g. Brodmann Areas 24 and 25, insular cortex), cortical areas that can be overactive in depression and which sit above the nasal epithelium. In contrast, NMDAR blockade in the dorsolateral PFC following systemic administration of ketamine may contribute to cognitive deficits. This novel view may help to explain how intravenous ketamine can treat the symptoms of depression yet worsen the symptoms of schizophrenia. PMID:25619798

78 FR 11216 - Enforcement Actions Summary

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-15

...] Enforcement Actions Summary AGENCY: Transportation Security Administration, DHS. ACTION: Notice of... an annual summary of all enforcement actions taken by TSA under the authority granted in the... public with an annual summary of all enforcement actions taken by TSA under this subsection; and include...

77 FR 12865 - Enforcement Actions Summary

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-02

...] Enforcement Actions Summary AGENCY: Transportation Security Administration, DHS. ACTION: Notice of... an annual summary of all enforcement actions taken by TSA under the authority granted in the... public with an annual summary of all enforcement actions taken by TSA under this subsection; and include...

76 FR 9357 - Enforcement Actions Summary

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-17

...] Enforcement Actions Summary AGENCY: Transportation Security Administration, DHS. ACTION: Notice of... an annual summary of all enforcement actions taken by TSA under the authority granted in the... to provide the public with an annual summary of all enforcement actions taken by TSA under this...

40 CFR 265.259 - Response actions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... response action plan must set forth the actions to be taken if the action leakage rate has been exceeded... section. (b) If the flow rate into the leak determination system exceeds the action leakage rate for any... notification that the action leakage rate has been exceeded, submit to the Regional Administrator the results...

5 CFR 930.113 - Corrective action.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 5 Administrative Personnel 2 2011-01-01 2011-01-01 false Corrective action. 930.113 Section 930....113 Corrective action. An agency will take adverse, disciplinary, or other appropriate action against... such action against an operator or an incidental operator: (a) The employee is convicted of operating...

5 CFR 930.113 - Corrective action.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Corrective action. 930.113 Section 930....113 Corrective action. An agency will take adverse, disciplinary, or other appropriate action against... such action against an operator or an incidental operator: (a) The employee is convicted of operating...

5 CFR 250.103 - Consequences of improper agency actions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Consequences of improper agency actions. 250.103 Section 250.103 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE... Consequences of improper agency actions. If OPM finds that an agency has taken an action contrary to a law...

The Action of Antidiabetic Plants of the Canadian James Bay Cree Traditional Pharmacopeia on Key Enzymes of Hepatic Glucose Homeostasis

PubMed Central

Nachar, Abir; Vallerand, Diane; Musallam, Lina; Lavoie, Louis; Arnason, John; Haddad, Pierre S.

2013-01-01

We determined the capacity of putative antidiabetic plants used by the Eastern James Bay Cree (Canada) to modulate key enzymes of gluconeogenesis and glycogen synthesis and key regulating kinases. Glucose-6-phosphatase (G6Pase) and glycogen synthase (GS) activities were assessed in cultured hepatocytes treated with crude extracts of seventeen plant species. Phosphorylation of AMP-dependent protein kinase (AMPK), Akt, and Glycogen synthase kinase-3 (GSK-3) were probed by Western blot. Seven of the seventeen plant extracts significantly decreased G6Pase activity, Abies balsamea and Picea glauca, exerting an effect similar to insulin. This action involved both Akt and AMPK phosphorylation. On the other hand, several plant extracts activated GS, Larix laricina and A. balsamea, far exceeding the action of insulin. We also found a significant correlation between GS stimulation and GSK-3 phosphorylation induced by plant extract treatments. In summary, three Cree plants stand out for marked effects on hepatic glucose homeostasis. P. glauca affects glucose production whereas L. laricina rather acts on glucose storage. However, A. balsamea has the most promising profile, simultaneously and powerfully reducing G6Pase and stimulating GS. Our studies thus confirm that the reduction of hepatic glucose production likely contributes to the therapeutic potential of several antidiabetic Cree traditional medicines. PMID:23864882

40 CFR 265.224 - Response actions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... action plan. The response action plan must set forth the actions to be taken if the action leakage rate... paragraph (b) of this section. (b) If the flow rate into the leak detection system exceeds the action leakage rate for any sump, the owner or operator must: (1) Notify the Regional Administrator in writing of...

40 CFR 264.223 - Response actions.

Code of Federal Regulations, 2010 CFR

2010-07-01

...) If the flow rate into the leak detection system exceeds the action leakage rate for any sump, the... action plan must set forth the actions to be taken if the action leakage rate has been exceeded. At a... action leakage rate has been exceeded, submit to the Regional Administrator the results of the analyses...

40 CFR 265.303 - Response actions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... section. (b) If the flow rate into the leak detection system exceeds the action leakage rate for any sump... response action plan must set forth the actions to be taken if the action leakage rate has been exceeded... notification that the action leakage rate has been exceeded, submit to the Regional Administrator the results...

5 CFR 1201.125 - Administrative law judge.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 5 Administrative Personnel 3 2013-01-01 2013-01-01 false Administrative law judge. 1201.125... § 1201.125 Administrative law judge. (a) An administrative law judge will hear a disciplinary action... administrative law judge will issue an initial decision on the complaint pursuant to 5 U.S.C. 557. The applicable...

Key Issues in the Modes of Action and Effects of Trichloroethylene Metabolites for Liver and Kidney Tumorigenesis

PubMed Central

Caldwell, Jane C.; Keshava, Nagalakshmi

2006-01-01

Trichloroethylene (TCE) exposure has been associated with increased risk of liver and kidney cancer in both laboratory animal and epidemiologic studies. The U.S. Environmental Protection Agency 2001 draft TCE risk assessment concluded that it is difficult to determine which TCE metabolites may be responsible for these effects, the key events involved in their modes of action (MOAs), and the relevance of these MOAs to humans. In this article, which is part of a mini-monograph on key issues in the health risk assessment of TCE, we present a review of recently published scientific literature examining the effects of TCE metabolites in the context of the preceding questions. Studies of the TCE metabolites dichloroacetic acid (DCA), trichloroacetic acid (TCA), and chloral hydrate suggest that both DCA and TCA are involved in TCE-induced liver tumorigenesis and that many DCA effects are consistent with conditions that increase the risk of liver cancer in humans. Studies of S-(1,2-dichlorovinyl)-l-cysteine have revealed a number of different possible cell signaling effects that may be related to kidney tumorigenesis at lower concentrations than those leading to cytotoxicity. Recent studies of trichloroethanol exploring an alternative hypothesis for kidney tumorigenesis have failed to establish the formation of formate as a key event for TCE-induced kidney tumors. Overall, although MOAs and key events for TCE-induced liver and kidney tumors have yet to be definitively established, these results support the likelihood that toxicity is due to multiple metabolites through several MOAs, none of which appear to be irrelevant to humans. PMID:16966105

45 CFR 32.12 - Right of action.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 45 Public Welfare 1 2010-10-01 2010-10-01 false Right of action. 32.12 Section 32.12 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION ADMINISTRATIVE WAGE GARNISHMENT § 32.12 Right of action. (a) The employer of a debtor subject to wage withholding pursuant to this part...

"Progress or Abuse--A Choice." A Study to Investigate the Need for Legislative and Administrative Actions Regarding Standards of Progress Provisions of the GI Bill and Class Session Requirements of the Veterans' Administration Regulations.

ERIC Educational Resources Information Center

Veterans Administration, Washington, DC.

The need for legislative and administrative action was examined in regard to the GI Bill and the satisfactory progress requirements and the "seat-time" requirements prescribed by regulation. Information is presented on the GI Bill Improvement Act of 1977 (P.L. 95-202), standards of progress of the veteran student, and contact time, or…

48 CFR 9901.314 - Informal actions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Informal actions. 9901.314... actions. The Chairman may take actions on behalf of the Board on administrative issues, as determined by the Chairman, without holding an official meeting of the members. However, details of the actions so...

48 CFR 9901.314 - Informal actions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 7 2011-10-01 2011-10-01 false Informal actions. 9901.314... actions. The Chairman may take actions on behalf of the Board on administrative issues, as determined by the Chairman, without holding an official meeting of the members. However, details of the actions so...

14 CFR 13.19 - Certificate action.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Certificate action. 13.19 Section 13.19... INVESTIGATIVE AND ENFORCEMENT PROCEDURES Legal Enforcement Actions § 13.19 Certificate action. (a) Under section... charges or other reasons upon which the Administrator bases the proposed action and, except in an...

77 FR 20779 - Committee on Administration and Management

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-06

... Committee on Administration and Management AGENCY: Administrative Conference of the United States. ACTION... Administration and Management of the Assembly of the Administrative Conference of the United States. The meeting... Committees,'' and then on ``Committee on Administration and Management.'' Comments may be submitted by email...

46 CFR 5.19 - Administrative Law Judge.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 1 2014-10-01 2014-10-01 false Administrative Law Judge. 5.19 Section 5.19 Shipping... REGULATIONS-PERSONNEL ACTION Definitions § 5.19 Administrative Law Judge. (a) An Administrative Law Judge... has delegated to Administrative Law Judges the authority to admonish, suspend, with or without...

46 CFR 5.19 - Administrative Law Judge.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 1 2012-10-01 2012-10-01 false Administrative Law Judge. 5.19 Section 5.19 Shipping... REGULATIONS-PERSONNEL ACTION Definitions § 5.19 Administrative Law Judge. (a) An Administrative Law Judge... has delegated to Administrative Law Judges the authority to admonish, suspend, with or without...

46 CFR 5.19 - Administrative Law Judge.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 1 2013-10-01 2013-10-01 false Administrative Law Judge. 5.19 Section 5.19 Shipping... REGULATIONS-PERSONNEL ACTION Definitions § 5.19 Administrative Law Judge. (a) An Administrative Law Judge... has delegated to Administrative Law Judges the authority to admonish, suspend, with or without...

46 CFR 5.19 - Administrative Law Judge.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 1 2011-10-01 2011-10-01 false Administrative Law Judge. 5.19 Section 5.19 Shipping... REGULATIONS-PERSONNEL ACTION Definitions § 5.19 Administrative Law Judge. (a) An Administrative Law Judge... has delegated to Administrative Law Judges the authority to admonish, suspend, with or without...

29 CFR 1625.30 - Administrative exemptions; procedures.

Code of Federal Regulations, 2013 CFR

2013-07-01

....30 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION AGE DISCRIMINATION IN EMPLOYMENT ACT Administrative Exemptions § 1625.30 Administrative exemptions; procedures. (a... discrimination in employment. Administrative action consistent with this statutory purpose may be taken under...

29 CFR 1625.30 - Administrative exemptions; procedures.

Code of Federal Regulations, 2012 CFR

2012-07-01

....30 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION AGE DISCRIMINATION IN EMPLOYMENT ACT Administrative Exemptions § 1625.30 Administrative exemptions; procedures. (a... discrimination in employment. Administrative action consistent with this statutory purpose may be taken under...

29 CFR 1625.30 - Administrative exemptions; procedures.

Code of Federal Regulations, 2011 CFR

2011-07-01

....30 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION AGE DISCRIMINATION IN EMPLOYMENT ACT Administrative Exemptions § 1625.30 Administrative exemptions; procedures. (a... discrimination in employment. Administrative action consistent with this statutory purpose may be taken under...

29 CFR 1625.30 - Administrative exemptions; procedures.

Code of Federal Regulations, 2014 CFR

2014-07-01

....30 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION AGE DISCRIMINATION IN EMPLOYMENT ACT Administrative Exemptions § 1625.30 Administrative exemptions; procedures. (a... discrimination in employment. Administrative action consistent with this statutory purpose may be taken under...

29 CFR 1625.30 - Administrative exemptions; procedures.

Code of Federal Regulations, 2010 CFR

2010-07-01

....30 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION AGE DISCRIMINATION IN EMPLOYMENT ACT Administrative Exemptions § 1625.30 Administrative exemptions; procedures. (a... discrimination in employment. Administrative action consistent with this statutory purpose may be taken under...

78 FR 25337 - Federal Aviation Administration

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-30

... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Agency Information Collection Activities: Requests for Comments; Clearance of Renewed Approval of Information Collection: Operations Specifications AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice and request for comments...

14 CFR 13.19 - Certificate action.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Certificate action. 13.19 Section 13.19... INVESTIGATIVE AND ENFORCEMENT PROCEDURES Legal Enforcement Actions § 13.19 Certificate action. (a) Under section... Administrator bases the proposed action and, except in an emergency, allows the holder to answer any charges and...

76 FR 45621 - Employment and Training Administration

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-29

... DEPARTMENT OF LABOR Employment and Training Administration Comment Request for Extension of... Administration. ACTION: Notice. SUMMARY: The Department of Labor (Department), as part of its continuing effort..., the Employment and Training Administration (ETA) is soliciting comments concerning the extension of...

49 CFR 386.54 - Administrative Law Judge.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 5 2011-10-01 2011-10-01 false Administrative Law Judge. 386.54 Section 386.54... General Rules and Hearings § 386.54 Administrative Law Judge. (a) Powers of an Administrative Law Judge. The Administrative Law Judge may take any action and may prescribe all necessary rules and regulations...

49 CFR 386.54 - Administrative Law Judge.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 5 2013-10-01 2013-10-01 false Administrative Law Judge. 386.54 Section 386.54... General Rules and Hearings § 386.54 Administrative Law Judge. (a) Powers of an Administrative Law Judge. The Administrative Law Judge may take any action and may prescribe all necessary rules and regulations...

49 CFR 386.54 - Administrative Law Judge.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 5 2010-10-01 2010-10-01 false Administrative Law Judge. 386.54 Section 386.54... General Rules and Hearings § 386.54 Administrative Law Judge. (a) Powers of an Administrative Law Judge. The Administrative Law Judge may take any action and may prescribe all necessary rules and regulations...

78 FR 18420 - Special Permit Applications Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-26

... Applications Actions AGENCY: Pipeline and Hazardous Materials Safety Administration (PHMSA), DOT. ACTION: Notice of actions on special permit applications. SUMMARY: In accordance with the procedures governing... Hazardous Material Regulations (49 CFR part 107, subpart B), notice is hereby given of the actions on...

75 FR 57820 - National Credit Union Administration Restoration Plan

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-22

... NATIONAL CREDIT UNION ADMINISTRATION National Credit Union Administration Restoration Plan AGENCY: National Credit Union Administration (NCUA). ACTION: Approval of National Credit Union Administration restoration plan. On September 16, 2010, the National Credit Union Administration (NCUA) implemented a...

41 CFR 105-57.012 - Actions prohibited by the employer.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Administration 57-ADMINISTRATION WAGE GARNISHMENT § 105-57.012 Actions prohibited by the employer. An employer may not discharge, refuse to employ, or take disciplinary action against the debtor due to the... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Actions prohibited by...

20 CFR 416.1402 - Administrative actions that are initial determinations.

Code of Federal Regulations, 2010 CFR

2010-04-01

... determinations. 416.1402 Section 416.1402 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Determinations, Administrative Review Process, and... preponderance of the evidence. We will state the important facts and give the reasons for our conclusions in the...

20 CFR 658.702 - Initial action by the Regional Administrator.

Code of Federal Regulations, 2010 CFR

2010-04-01

... JS regulations. (b) Wherever a Regional Administrator discovers or is apprised of possible State agency violations of JS regulations by the review and assessment activities under subpart G of this part... a State agency has violated JS regulations. (c) The Regional Administrator shall accept complaints...

A human relevance investigation of PPARα-mediated key events in the hepatocarcinogenic mode of action of propaquizafop in rats.

PubMed

Strupp, Christian; Bomann, Werner H; Spézia, François; Gervais, Frédéric; Forster, Roy; Richert, Lysiane; Singh, Pramila

2018-06-01

Propaquizafop is an herbicide with demonstrated hepatocarcinogenic activity in rodents. A rodent-specific mode of action (MOA) in the liver via activation of peroxisome proliferator-activated receptor α (PPARα) has been postulated based on existing data. Experience with PPARα-inducing pharmaceuticals indicates a lack of human relevance of this MOA. The objective of the present investigation was to evaluate the dependency of early key events leading to liver tumors on PPARα activation in wildtype (WT) compared to PPARα-knockout (KO) rats following 2 weeks exposure to 75, 500 and 1000 ppm propaquizafop in the diet. In WT rats, both WY-14643 (50 mg/kg bw/day) and propaquizafop (dose-dependently) induced marked increases in liver weights, correlating with liver enlargement and hepatocellular hypertrophy, along with increased CYP4A and acyl-CoA oxidase mRNA expression and enzyme activities versus controls, while in KO rats liver weight was mildly increased only at the high dose with minimal microscopic correlates and without any changes in liver peroxisomal or CYP4A activities. In addition, BrdU labeling resulted in higher numbers and density of positive hepatocytes versus controls in WT but not in KO rats, indicating increased mitotic activity and cell proliferation only in WT rats, thus confirming the PPARα-dependency of the biochemical and histological changes in the liver. Based on an assessment of the results of this investigation, together with existing propaquizafop data according to the MOA-Human Relevance Framework, we conclude that liver tumors observed in rodents after dietary administration of propaquizafop do not pose a relevant health risk to humans. Copyright © 2018 Elsevier Inc. All rights reserved.

Women as Academic Administrators in the Age of Affirmative Action.

ERIC Educational Resources Information Center

Palley, Marian Lief

1978-01-01

Data indicate that, once academic women select or are selected for administrative careers, quantitative opportunities are available to those who seem to be approximately equivalent to men. However, if qualitative measures are assessed, it becomes clear that women administrators do not fare as well as men. (Author)

5 CFR 315.909 - Relationship to other actions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Relationship to other actions. 315.909 Section 315.909 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS CAREER... Position § 315.909 Relationship to other actions. (a) If an employee is required to concurrently serve both...

Differential Effects of Oral and Intravenous Lipid Administration on Key Molecules Related to Energy Homeostasis

PubMed Central

Vamvini, Maria T.; Hamnvik, Ole-Petter; Sahin-Efe, Ayse; Gavrieli, Anna; Dincer, Fadime; Farr, Olivia M.

2016-01-01

Context: The spectrum of lipid-induced changes in the secretion of hormones important in energy homeostasis has not yet been fully elucidated. Objective: To identify potential incretin-like effects in response to lipid administration, we examined the short-term effect of iv vs oral lipids on key molecules regulating energy homeostasis. Design, Intervention, and Participants: After a 10-hour overnight fast, 26 subjects were randomized to receive an oral lipid load, a 10% iv lipid emulsion, a 20% iv lipid emulsion, or an iv saline infusion. We obtained blood samples at 30-minute intervals for the first 2 hours and hourly thereafter for a total of 6 hours. Main Outcome Measures: Circulating levels of insulin, glucose, c-peptide, free fatty acids, incretins (glucagon-like peptide-1, gastric inhibitory polypeptide), glucagon, peptide YY, ghrelin, fibroblast growth factor 21, fetuin A, irisin, omentin, and adiponectin were measured. Results: Oral lipid ingestion resulted in higher glucagon-like peptide-1, gastric inhibitory polypeptide, glucagon, and peptide YY levels, compared with the other three groups (incremental area under the curve P = .003, P < .001, P < .001, P < .001, respectively). The 20% lipid emulsion, leading to higher free fatty acid levels, resulted in greater insulin, c-peptide, and fibroblast growth factor 21 responses compared with placebo and the other two groups (incremental area under the curve P = .002, P = .005, P < .001, P < .001, respectively). Omentin, adiponectin, fetuin A, and irisin levels were not affected by either mode of lipid administration. Conclusions: Metabolic responses to lipids depend on the route of administration. Only iv lipids trigger a dose-dependent fibroblast growth factor 21 secretion, which is nonglucagon mediated. Intravenous lipids also induce hyperinsulinemia without concurrent decreases in glucose, a phenomenon observed in insulin-resistant states. Orally administered lipids mostly affect gastrointestinal tract

38 CFR 18.550 - Exhaustion of administrative remedies.

Code of Federal Regulations, 2010 CFR

2010-07-01

... administrative remedies. 18.550 Section 18.550 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS..., Conciliation, and Enforcement Procedures § 18.550 Exhaustion of administrative remedies. (a) A complainant may file a civil action following the exhaustion of administrative remedies under the Act. Administrative...

47 CFR 1.1906 - Informal action.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 47 Telecommunication 1 2011-10-01 2011-10-01 false Informal action. 1.1906 Section 1.1906... United States General Provisions § 1.1906 Informal action. Nothing contained in these regulations is intended to preclude utilization of informal administrative actions or remedies which may be available...

47 CFR 1.1906 - Informal action.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 47 Telecommunication 1 2010-10-01 2010-10-01 false Informal action. 1.1906 Section 1.1906... United States General Provisions § 1.1906 Informal action. Nothing contained in these regulations is intended to preclude utilization of informal administrative actions or remedies which may be available...

23 CFR 771.137 - International actions.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 23 Highways 1 2010-04-01 2010-04-01 false International actions. 771.137 Section 771.137 Highways... IMPACT AND RELATED PROCEDURES § 771.137 International actions. (a) The requirements of this part apply to: (1) Administration actions significantly affecting the environment of a foreign nation not...

NASA, NOAA administrators nominated

NASA Astrophysics Data System (ADS)

Richman, Barbara T.

President Ronald Reagan recently said he intended to nominate James Montgomery Beggs as NASA Administrator and John V. Byrne as NOAA Administrator. These two positions are key scientific posts that have been vacant since the start of the Reagan administration on January 20. The President also said he intends to nominate Hans Mark as NASA Deputy Administrator. At press time, Reagan had not designated his nominee for the director of the Office of Science and Technology Policy.

Key Lessons Learned from Moffitt's Molecular Tumor Board: The Clinical Genomics Action Committee Experience.

PubMed

Knepper, Todd C; Bell, Gillian C; Hicks, J Kevin; Padron, Eric; Teer, Jamie K; Vo, Teresa T; Gillis, Nancy K; Mason, Neil T; McLeod, Howard L; Walko, Christine M

2017-02-01

The increasing practicality of genomic sequencing technology has led to its incorporation into routine clinical practice. Successful identification and targeting of driver genomic alterations that provide proliferative and survival advantages to tumor cells have led to approval and ongoing development of several targeted cancer therapies. Within many major cancer centers, molecular tumor boards are constituted to shepherd precision medicine into clinical practice. In July 2014, the Clinical Genomics Action Committee (CGAC) was established as the molecular tumor board companion to the Personalized Medicine Clinical Service (PMCS) at Moffitt Cancer Center in Tampa, Florida. The processes and outcomes of the program were assessed in order to help others move into the practice of precision medicine. Through the establishment and initial 1,400 patients of the PMCS and its associated molecular tumor board at a major cancer center, five practical lessons of broad applicability have been learned: transdisciplinary engagement, the use of the molecular report as an aid to clinical management, clinical actionability, getting therapeutic options to patients, and financial considerations. Value to patients includes access to cutting-edge practice merged with individualized preferences in treatment and care. Genomic-driven cancer medicine is increasingly becoming a part of routine clinical practice. For successful implementation of precision cancer medicine, strategically organized molecular tumor boards are critical to provide objective evidence-based translation of observed molecular alterations into patient-centered clinical action. Molecular tumor board implementation models along with clinical and economic outcomes will define future treatment standards. The Oncologist 2017;22:144-151 Implications for Practice: It is clear that the increasing practicality of genetic tumor sequencing technology has led to its incorporation as part of routine clinical practice. Subsequently

Key Lessons Learned from Moffitt's Molecular Tumor Board: The Clinical Genomics Action Committee Experience

PubMed Central

Knepper, Todd C.; Bell, Gillian C.; Hicks, J. Kevin; Padron, Eric; Teer, Jamie K.; Vo, Teresa T.; Gillis, Nancy K.; Mason, Neil T.; Walko, Christine M.

2017-01-01

Abstract Background. The increasing practicality of genomic sequencing technology has led to its incorporation into routine clinical practice. Successful identification and targeting of driver genomic alterations that provide proliferative and survival advantages to tumor cells have led to approval and ongoing development of several targeted cancer therapies. Within many major cancer centers, molecular tumor boards are constituted to shepherd precision medicine into clinical practice. Materials and Methods. In July 2014, the Clinical Genomics Action Committee (CGAC) was established as the molecular tumor board companion to the Personalized Medicine Clinical Service (PMCS) at Moffitt Cancer Center in Tampa, Florida. The processes and outcomes of the program were assessed in order to help others move into the practice of precision medicine. Results. Through the establishment and initial 1,400 patients of the PMCS and its associated molecular tumor board at a major cancer center, five practical lessons of broad applicability have been learned: transdisciplinary engagement, the use of the molecular report as an aid to clinical management, clinical actionability, getting therapeutic options to patients, and financial considerations. Value to patients includes access to cutting‐edge practice merged with individualized preferences in treatment and care. Conclusions. Genomic‐driven cancer medicine is increasingly becoming a part of routine clinical practice. For successful implementation of precision cancer medicine, strategically organized molecular tumor boards are critical to provide objective evidence‐based translation of observed molecular alterations into patient‐centered clinical action. Molecular tumor board implementation models along with clinical and economic outcomes will define future treatment standards. Implications for Practice. It is clear that the increasing practicality of genetic tumor sequencing technology has led to its incorporation as part

Administrative Leadership as Projection, Social Control, and Action.

ERIC Educational Resources Information Center

Reed, Donald B.

Over the past 50 years, theoretical and methodological problems have plagued the study of leadership. This paper, proposing an alternative theory, argues that leadership has three fundamental components: projection and social control, which are linked by action. Projection is the visualization of a project to be completed. Educational…

76 FR 2745 - Federal Aviation Administration

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-14

... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Eighty-Fourth Meeting: RTCA Special Committee 159: Global Positioning System (GPS) AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of RTCA Special Committee 159 meeting: Global Positioning System (GPS). SUMMARY: The FAA is...

Culture and Commitment: The Key to the Creation of an Action Learning Organization

ERIC Educational Resources Information Center

Hind, Matthew; Koenigsberger, John

2007-01-01

This article examines the introduction and practice of action learning into a highly volatile, commercial environment. During nine years of action learning projects, the impact on individuals, the action learning sets into which they were formed, the organization and its structure and the organizational culture were evaluated. The article…

20 CFR 410.610 - Administrative actions that are initial determinations.

Code of Federal Regulations, 2010 CFR

2010-04-01

... determinations. 410.610 Section 410.610 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL COAL MINE...) Withdrawal of claim or cancellation of withdrawal request. When a request for withdrawal of a claim, or a request for cancellation of a “request for withdrawal” of a claim, is denied by the Administration, the...

18 CFR 401.89 - Action by the Commission.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 18 Conservation of Power and Water Resources 2 2011-04-01 2011-04-01 false Action by the Commission. 401.89 Section 401.89 Conservation of Power and Water Resources DELAWARE RIVER BASIN COMMISSION ADMINISTRATIVE MANUAL RULES OF PRACTICE AND PROCEDURE Administrative and Other Hearings § 401.89 Action by the...

ELECTROCARDIOGRAPHIC CHANGES IN RABBITS SUBJECTED TO THE CHRONIC ACTION OF RADIOACTIVE ZINC DURING INTRAVENOUS ADMINISTRATION OF ADRENALINE AND INHALATION OF AMMONIA (in Russian)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ovakimov, V.G.; Bibikhin, L.N.; Saitanov, A.O.

1963-09-01

The employment of pharmacological loadings (administration of adrenaline and inhalation of ammonia) in rabbits subjected to the chronic action of radioactive zinc (1 and 10 mu C/kg) disclosed changes in the sensitivity of adrenoreactive systems of the myocardium (in adrenaline test) and an altered intensity and duration of reflex bradycardia (in ammonia test). (auth)

21 CFR 1309.41 - Administrative review generally.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 9 2013-04-01 2013-04-01 false Administrative review generally. 1309.41 Section... MANUFACTURERS, DISTRIBUTORS, IMPORTERS AND EXPORTERS OF LIST I CHEMICALS Action on Applications for Registration: Revocation Or Suspension of Registration § 1309.41 Administrative review generally. The Administrator may...

21 CFR 1309.41 - Administrative review generally.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Administrative review generally. 1309.41 Section... MANUFACTURERS, DISTRIBUTORS, IMPORTERS AND EXPORTERS OF LIST I CHEMICALS Action on Applications for Registration: Revocation Or Suspension of Registration § 1309.41 Administrative review generally. The Administrator may...

21 CFR 1309.41 - Administrative review generally.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 9 2011-04-01 2011-04-01 false Administrative review generally. 1309.41 Section... MANUFACTURERS, DISTRIBUTORS, IMPORTERS AND EXPORTERS OF LIST I CHEMICALS Action on Applications for Registration: Revocation Or Suspension of Registration § 1309.41 Administrative review generally. The Administrator may...

21 CFR 1309.41 - Administrative review generally.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 9 2014-04-01 2014-04-01 false Administrative review generally. 1309.41 Section... MANUFACTURERS, DISTRIBUTORS, IMPORTERS AND EXPORTERS OF LIST I CHEMICALS Action on Applications for Registration: Revocation Or Suspension of Registration § 1309.41 Administrative review generally. The Administrator may...

21 CFR 1309.41 - Administrative review generally.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 9 2012-04-01 2012-04-01 false Administrative review generally. 1309.41 Section... MANUFACTURERS, DISTRIBUTORS, IMPORTERS AND EXPORTERS OF LIST I CHEMICALS Action on Applications for Registration: Revocation Or Suspension of Registration § 1309.41 Administrative review generally. The Administrator may...

Putting program evaluation to work: a framework for creating actionable knowledge for suicide prevention practice.

PubMed

Wilkins, Natalie; Thigpen, Sally; Lockman, Jennifer; Mackin, Juliette; Madden, Mary; Perkins, Tamara; Schut, James; Van Regenmorter, Christina; Williams, Lygia; Donovan, John

2013-06-01

The economic and human cost of suicidal behavior to individuals, families, communities, and society makes suicide a serious public health concern, both in the US and around the world. As research and evaluation continue to identify strategies that have the potential to reduce or ultimately prevent suicidal behavior, the need for translating these findings into practice grows. The development of actionable knowledge is an emerging process for translating important research and evaluation findings into action to benefit practice settings. In an effort to apply evaluation findings to strengthen suicide prevention practice, the Centers for Disease Control and Prevention (CDC) and the Substance Abuse and Mental Health Services Administration (SAMHSA) supported the development of three actionable knowledge products that make key findings and lessons learned from youth suicide prevention program evaluations accessible and useable for action. This paper describes the actionable knowledge framework (adapted from the knowledge transfer literature), the three products that resulted, and recommendations for further research into this emerging method for translating research and evaluation findings and bridging the knowledge-action gap.

40 CFR 77.4 - Administrator's action on proposed offset plans.

Code of Federal Regulations, 2012 CFR

2012-07-01

... representative. The Administrator will also give notice of any approval in the Federal Register. The plans will... response to public comments submitted on the draft offset plan or disapproval of a draft offset plan... offset plan. The Administrator will serve a copy of any approved offset plan and the response to comments...

40 CFR 77.4 - Administrator's action on proposed offset plans.

Code of Federal Regulations, 2014 CFR

2014-07-01

... representative. The Administrator will also give notice of any approval in the Federal Register. The plans will... response to public comments submitted on the draft offset plan or disapproval of a draft offset plan... offset plan. The Administrator will serve a copy of any approved offset plan and the response to comments...

40 CFR 77.4 - Administrator's action on proposed offset plans.

Code of Federal Regulations, 2010 CFR

2010-07-01

... representative. The Administrator will also give notice of any approval in the Federal Register. The plans will... response to public comments submitted on the draft offset plan or disapproval of a draft offset plan... offset plan. The Administrator will serve a copy of any approved offset plan and the response to comments...

40 CFR 77.4 - Administrator's action on proposed offset plans.

Code of Federal Regulations, 2011 CFR

2011-07-01

... representative. The Administrator will also give notice of any approval in the Federal Register. The plans will... response to public comments submitted on the draft offset plan or disapproval of a draft offset plan... offset plan. The Administrator will serve a copy of any approved offset plan and the response to comments...

28 CFR 544.75 - Disciplinary action.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Disciplinary action. 544.75 Section 544... EDUCATION Literacy Program § 544.75 Disciplinary action. As with other mandatory programs, such as work assignments, staff may take disciplinary action against an inmate lacking a GED credential or high school...

29 CFR 1450.6 - Informal action.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 29 Labor 4 2010-07-01 2010-07-01 false Informal action. 1450.6 Section 1450.6 Labor Regulations... UNITED STATES General Provisions § 1450.6 Informal action. Nothing contained in this regulation is intended to preclude utilization of informal administrative actions or remedies which may be available. ...

5 CFR 250.103 - Consequences of improper agency actions.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 5 Administrative Personnel 1 2011-01-01 2011-01-01 false Consequences of improper agency actions. 250.103 Section 250.103 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL MANAGEMENT IN AGENCIES Authority for Personnel Actions in Agencies § 250.103...

5 CFR 731.105 - Authority to take suitability actions.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 5 Administrative Personnel 2 2012-01-01 2012-01-01 false Authority to take suitability actions. 731.105 Section 731.105 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) SUITABILITY Scope § 731.105 Authority to take suitability actions. (a...

5 CFR 731.105 - Authority to take suitability actions.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 5 Administrative Personnel 2 2011-01-01 2011-01-01 false Authority to take suitability actions. 731.105 Section 731.105 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) SUITABILITY Scope § 731.105 Authority to take suitability actions. (a...

5 CFR 731.105 - Authority to take suitability actions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Authority to take suitability actions. 731.105 Section 731.105 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) SUITABILITY Scope § 731.105 Authority to take suitability actions. (a...

5 CFR 731.105 - Authority to take suitability actions.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 5 Administrative Personnel 2 2013-01-01 2013-01-01 false Authority to take suitability actions. 731.105 Section 731.105 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) SUITABILITY Scope § 731.105 Authority to take suitability actions. (a...

5 CFR 731.105 - Authority to take suitability actions.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 5 Administrative Personnel 2 2014-01-01 2014-01-01 false Authority to take suitability actions. 731.105 Section 731.105 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) SUITABILITY Scope § 731.105 Authority to take suitability actions. (a...

75 FR 60768 - Single-Ingredient Oral Colchicine Products; Enforcement Action Dates

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-01

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2010-N-0257] Single-Ingredient Oral Colchicine Products; Enforcement Action Dates AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA or agency) is announcing its...

75 FR 34960 - Import Administration IA ACCESS Pilot Program

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-21

... DEPARTMENT OF COMMERCE International Trade Administration 19 CFR Part 351 [Docket No. 100602237-0250-02] Import Administration IA ACCESS Pilot Program AGENCY: Import Administration, International Trade Administration, Department of Commerce. ACTION: Public notice and request for comments; correction...

75 FR 37877 - Federal Highway Administration (FHWA), DOT.

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-30

... DEPARTMENT OF TRANSPORTATION Federal Highway Administration Buy America Waiver Notification Federal Highway Administration (FHWA), DOT. ACTION: Notice. SUMMARY: This notice provides information... Program Administration, (202) 366-1562, or via e-mail at [email protected] . For legal questions...

29 CFR 35.40 - Exhaustion of administrative remedies.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 29 Labor 1 2010-07-01 2010-07-01 true Exhaustion of administrative remedies. 35.40 Section 35.40... Enforcement Procedures § 35.40 Exhaustion of administrative remedies. (a) A complainant may file a civil action under the Act following the exhaustion of administrative remedies. Administrative remedies are...

34 CFR 110.39 - Exhaustion of administrative remedies.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 34 Education 1 2010-07-01 2010-07-01 false Exhaustion of administrative remedies. 110.39 Section... administrative remedies. (a) A complainant may file a civil action following the exhaustion of administrative remedies under the Act. Administrative remedies are exhausted if— (1) One hundred eighty days have elapsed...

29 CFR 35.40 - Exhaustion of administrative remedies.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 29 Labor 1 2011-07-01 2011-07-01 false Exhaustion of administrative remedies. 35.40 Section 35.40... Enforcement Procedures § 35.40 Exhaustion of administrative remedies. (a) A complainant may file a civil action under the Act following the exhaustion of administrative remedies. Administrative remedies are...

48 CFR 9901.310 - Board action.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Board action. 9901.310... PROCUREMENT POLICY, OFFICE OF MANAGEMENT AND BUDGET ADMINISTRATION RULES AND PROCEDURES 9901.310 Board action. Board action shall be by majority vote of the members present and voting, except that any vote to...

48 CFR 9901.310 - Board action.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 7 2011-10-01 2011-10-01 false Board action. 9901.310... PROCUREMENT POLICY, OFFICE OF MANAGEMENT AND BUDGET ADMINISTRATION RULES AND PROCEDURES 9901.310 Board action. Board action shall be by majority vote of the members present and voting, except that any vote to...

77 FR 58213 - Actions on Special Permit Applications

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-19

... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration Actions on.... ACTION: Notice of actions on Special Permit Applications. SUMMARY: In accordance with the procedures... actions on special permits applications in (August to August 2012). The mode of transportation involved...

32 CFR 1602.2 - Administrative classification.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 6 2012-07-01 2012-07-01 false Administrative classification. 1602.2 Section 1602.2 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM DEFINITIONS § 1602.2 Administrative classification. A reclassification action relating to a registrant's claim...

32 CFR 1602.2 - Administrative classification.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 6 2014-07-01 2014-07-01 false Administrative classification. 1602.2 Section 1602.2 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM DEFINITIONS § 1602.2 Administrative classification. A reclassification action relating to a registrant's claim...

32 CFR 1602.2 - Administrative classification.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 6 2013-07-01 2013-07-01 false Administrative classification. 1602.2 Section 1602.2 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM DEFINITIONS § 1602.2 Administrative classification. A reclassification action relating to a registrant's claim...

32 CFR 1602.2 - Administrative classification.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 6 2011-07-01 2011-07-01 false Administrative classification. 1602.2 Section 1602.2 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM DEFINITIONS § 1602.2 Administrative classification. A reclassification action relating to a registrant's claim...

32 CFR 1602.2 - Administrative classification.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 6 2010-07-01 2010-07-01 false Administrative classification. 1602.2 Section 1602.2 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM DEFINITIONS § 1602.2 Administrative classification. A reclassification action relating to a registrant's claim...

Caloric restriction and IGF-I administration promote rabbit fecundity: Possible interrelationships and mechanisms of action.

PubMed

Sirotkin, Alexander V; Florkovičová, Iveta Koničková; Švarcová, Olga Østrup; Rafay, Jan; Laurincik, Jozef; Harrath, Abdel Halim

2017-03-01

. Addition of IGF-I to culture medium reduced accumulation of bax, MAPK, and IGF-I and promoted PKA accumulation and E 2 release. CR promoted the stimulatory effect of IGF-I on E 2 output. Thus, CR can increase rabbit fecundity, probably via changes in IGF-I, leptin and steroid hormones released, which in turn can affect ovarian cell cycle, apoptosis, and response to IGF-I. Furthermore, they demonstrate the stimulatory influence of IGF-I on rabbit fecundity, which was associated with changes in plasma leptin, E 2 and ovarian cell apoptosis, PKA, MAPK, IGF-I and E 2 release. The promotion of IGF-I output by CR and the ability of IGF-I to mimic/replace but not to modify CR effects on fecundity, plasma IGF-I, and ovarian cell apoptosis suggest that IGF can mediate the action of CR on these reproductive indexes. In contrast, differences in the action of CR and IGF-I on other hormones, ovarian cell proliferation, protein kinases and IGF-I suggest that CR action on these indexes is not mediated by IGF-I. We thus demonstrate that both CR and IGF-I administration can increase rabbit fecundity, and that their effects can be mediated by changes in reproductive hormones, ovarian cell proliferation, apoptosis, and the response of ovarian cells to IGF-I. Copyright © 2016 Elsevier Inc. All rights reserved.

40 CFR 1.27 - Offices of the Associate Administrators.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Agency decision-making processes, assessing the impact of Headquarters actions on Regional operations... Regional Operations. The Office of Regional Operations, under the supervision of an Associate Administrator... communications link between the Administrator/Deputy Administrator and the Regional Administrators. It provides a...

78 FR 62417 - Import Administration; Change of Agency Name

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-22

... DEPARTMENT OF COMMERCE International Trade Administration 19 CFR Parts 351, 354, and 356 RIN 0625-AA97 [Docket No. 130927845-3845-01] Import Administration; Change of Agency Name AGENCY: Import Administration, International Trade Administration, Commerce. ACTION: Final rule; nomenclature change. SUMMARY...

10 CFR 4.340 - Exhaustion of administrative remedies.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 1 2010-01-01 2010-01-01 false Exhaustion of administrative remedies. 4.340 Section 4.340... administrative remedies. (a) A complainant may file a civil action following the exhaustion of administrative remedies under the Act. Administrative remedies are exhausted if— (1) 180 days have elapsed since the...

77 FR 64843 - Actions on Special Permit Applications

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-23

... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration Actions on.... ACTION: Notice of actions on Special Permit Applications. SUMMARY: In accordance with the procedures...'s Hazardous Material Regulations (49 CFR part 107, subpart B), notice is hereby given of the actions...

78 FR 24305 - Actions on Special Permit Applications

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-24

... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration Actions on.... ACTION: Notice of actions on Special Permit Applications. SUMMARY: In accordance with the procedures...'s Hazardous Material Regulations (49 CFR Part 107, Subpart B), notice is hereby given of the actions...

77 FR 49483 - Actions on Special Permit Applications

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-16

... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration Actions on.... ACTION: Notice of actions on Special Permit Applications. SUMMARY: In accordance with the procedures...'s Hazardous Material Regulations (49 CFR Part 107, Subpart B), notice is hereby given of the actions...

78 FR 30394 - Actions on Special Permit Applications

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-22

... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration Actions on.... ACTION: Notice of actions on Special Permit Applications. SUMMARY: In accordance with the procedures...'s Hazardous Material Regulations (49 CFR part 107, subpart B), notice is hereby given of the actions...

77 FR 29450 - Actions on Special Permit Applications

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-17

... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration Actions on.... ACTION: Notice of actions on Special Permit Applications. SUMMARY: In accordance with the procedures...'s Hazardous Material Regulations (49 CFR part 107, subpart B), notice is hereby given of the actions...

34 CFR 303.424 - Civil action.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 34 Education 2 2011-07-01 2010-07-01 true Civil action. 303.424 Section 303.424 Education... Civil action. Any party aggrieved by the findings and decision regarding an administrative complaint has the right to bring a civil action in State or Federal court under section 639(a)(1) of the Act...

34 CFR 303.424 - Civil action.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 34 Education 2 2010-07-01 2010-07-01 false Civil action. 303.424 Section 303.424 Education... Civil action. Any party aggrieved by the findings and decision regarding an administrative complaint has the right to bring a civil action in State or Federal court under section 639(a)(1) of the Act...

76 FR 7893 - FAA Policy Statement on Expungement of Certain Enforcement Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-11

... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration FAA Policy Statement on Expungement of Certain Enforcement Actions AGENCY: Federal Aviation Administration, DOT. ACTION: Policy statement... policy. On August 1, 2010, the Airline Safety and Federal Aviation Administration Extension Act of 2010...

40 CFR 73.84 - Administrator's action on applications.

Code of Federal Regulations, 2013 CFR

2013-07-01

... PROGRAMS (CONTINUED) SULFUR DIOXIDE ALLOWANCE SYSTEM Energy Conservation and Renewable Energy Reserve § 73... categories of qualified renewable energy generation enumerated in § 73.81(c)(2)(i) and appendix A(3.1-3.4... conservation measures or renewable energy generation. (1) The Administrator will not award allowances to more...

40 CFR 73.84 - Administrator's action on applications.

Code of Federal Regulations, 2012 CFR

2012-07-01

... PROGRAMS (CONTINUED) SULFUR DIOXIDE ALLOWANCE SYSTEM Energy Conservation and Renewable Energy Reserve § 73... categories of qualified renewable energy generation enumerated in § 73.81(c)(2)(i) and appendix A(3.1-3.4... conservation measures or renewable energy generation.(1) The Administrator will not award allowances to more...

40 CFR 73.84 - Administrator's action on applications.

Code of Federal Regulations, 2014 CFR

2014-07-01

... PROGRAMS (CONTINUED) SULFUR DIOXIDE ALLOWANCE SYSTEM Energy Conservation and Renewable Energy Reserve § 73... categories of qualified renewable energy generation enumerated in § 73.81(c)(2)(i) and appendix A(3.1-3.4... conservation measures or renewable energy generation. (1) The Administrator will not award allowances to more...

40 CFR 73.84 - Administrator's action on applications.

Code of Federal Regulations, 2011 CFR

2011-07-01

... PROGRAMS (CONTINUED) SULFUR DIOXIDE ALLOWANCE SYSTEM Energy Conservation and Renewable Energy Reserve § 73... categories of qualified renewable energy generation enumerated in § 73.81(c)(2)(i) and appendix A(3.1-3.4... conservation measures or renewable energy generation.(1) The Administrator will not award allowances to more...

40 CFR 73.84 - Administrator's action on applications.

Code of Federal Regulations, 2010 CFR

2010-07-01

... PROGRAMS (CONTINUED) SULFUR DIOXIDE ALLOWANCE SYSTEM Energy Conservation and Renewable Energy Reserve § 73... categories of qualified renewable energy generation enumerated in § 73.81(c)(2)(i) and appendix A(3.1-3.4... conservation measures or renewable energy generation.(1) The Administrator will not award allowances to more...

Developing an Action Concept Inventory

ERIC Educational Resources Information Center

McGinness, Lachlan P.; Savage, C. M.

2016-01-01

We report on progress towards the development of an Action Concept Inventory (ACI), a test that measures student understanding of action principles in introductory mechanics and optics. The ACI also covers key concepts of many-paths quantum mechanics, from which classical action physics arises. We used a multistage iterative development cycle for…

78 FR 63380 - Farm Credit Administration Board Policy Statements

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-24

... FARM CREDIT ADMINISTRATION 12 CFR Chapter VI Farm Credit Administration Board Policy Statements AGENCY: Farm Credit Administration. ACTION: Notice of policy statements and index. SUMMARY: The Farm Credit Administration (FCA), as part of its annual public notification process, is publishing for notice...

Action of Neurotransmitter: A Key to Unlock the AgRP Neuron Feeding Circuit

PubMed Central

Liu, Tiemin; Wang, Qian; Berglund, Eric D.; Tong, Qingchun

2013-01-01

The current obesity epidemic and lack of efficient therapeutics demand a clear understanding of the mechanism underlying body weight regulation. Despite intensive research focus on obesity pathogenesis, an effective therapeutic strategy to treat and cure obesity is still lacking. Exciting studies in last decades have established the importance of hypothalamic agouti-related protein-expressing neurons (AgRP neurons) in the regulation of body weight homeostasis. AgRP neurons are both required and sufficient for feeding regulation. The activity of AgRP neurons is intricately regulated by nutritional hormones as well as synaptic inputs from upstream neurons. Changes in AgRP neuron activity lead to alterations in the release of mediators, including neuropeptides Neuropeptide Y (NPY) and AgRP, and fast-acting neurotransmitter GABA. Recent studies based on mouse genetics, novel optogenetics, and designer receptor exclusively activated by designer drugs have identified a critical role for GABA release from AgRP neurons in the parabrachial nucleus and paraventricular hypothalamus in feeding control. This review will summarize recent findings about AgRP neuron-mediated control of feeding circuits with a focus on the role of neurotransmitters. Given the limited knowledge on feeding regulation, understanding the action of neurotransmitters may be a key to unlock neurocircuitry that governs feeding. PMID:23346045

42 CFR 93.506 - Authority of the Administrative Law Judge.

Code of Federal Regulations, 2011 CFR

2011-10-01

... POLICIES ON RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions Hearing Process § 93.506 Authority of the Administrative Law Judge. (a) The ALJ assigned... communication; (17) Take action against any party for failing to follow an order or procedure or for disruptive...

INFORMAS (International Network for Food and Obesity/non-communicable diseases Research, Monitoring and Action Support): overview and key principles.

PubMed

Swinburn, B; Sacks, G; Vandevijvere, S; Kumanyika, S; Lobstein, T; Neal, B; Barquera, S; Friel, S; Hawkes, C; Kelly, B; L'abbé, M; Lee, A; Ma, J; Macmullan, J; Mohan, S; Monteiro, C; Rayner, M; Sanders, D; Snowdon, W; Walker, C

2013-10-01

Non-communicable diseases (NCDs) dominate disease burdens globally and poor nutrition increasingly contributes to this global burden. Comprehensive monitoring of food environments, and evaluation of the impact of public and private sector policies on food environments is needed to strengthen accountability systems to reduce NCDs. The International Network for Food and Obesity/NCDs Research, Monitoring and Action Support (INFORMAS) is a global network of public-interest organizations and researchers that aims to monitor, benchmark and support public and private sector actions to create healthy food environments and reduce obesity, NCDs and their related inequalities. The INFORMAS framework includes two 'process' modules, that monitor the policies and actions of the public and private sectors, seven 'impact' modules that monitor the key characteristics of food environments and three 'outcome' modules that monitor dietary quality, risk factors and NCD morbidity and mortality. Monitoring frameworks and indicators have been developed for 10 modules to provide consistency, but allowing for stepwise approaches ('minimal', 'expanded', 'optimal') to data collection and analysis. INFORMAS data will enable benchmarking of food environments between countries, and monitoring of progress over time within countries. Through monitoring and benchmarking, INFORMAS will strengthen the accountability systems needed to help reduce the burden of obesity, NCDs and their related inequalities. © 2013 The Authors. Obesity Reviews published by John Wiley & Sons Ltd on behalf of the International Association for the Study of Obesity.

40 CFR 264.222 - Action leakage rate.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Action leakage rate. 264.222 Section... Impoundments § 264.222 Action leakage rate. (a) The Regional Administrator shall approve an action leakage rate for surface impoundment units subject to § 264.221 (c) or (d). The action leakage rate is the maximum...

40 CFR 264.252 - Action leakage rate.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Action leakage rate. 264.252 Section... Piles § 264.252 Action leakage rate. (a) The Regional Administrator shall approve an action leakage rate for waste pile units subject to § 264.251(c) or (d). The action leakage rate is the maximum design...

76 FR 65183 - National Oceanic and Atmospheric Administration

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-20

... DEPARTMENT OF COMMERCE National Oceanic and Atmospheric Administration National Climate Assessment... Oceanic and Atmospheric Administration (NOAA), Department of Commerce (DOC). ACTION: Notice of open..., National Oceanic and Atmospheric Administration. [FR Doc. 2011-27113 Filed 10-19-11; 8:45 am] BILLING CODE...

Enhanced actions of insulin-like growth factor-I and interferon-alpha co-administration in experimental cirrhosis.

PubMed

Tutau, Federico; Rodríguez-Ortigosa, Carlos; Puche, Juan Enrique; Juanarena, Nerea; Monreal, Iñigo; García Fernández, María; Clavijo, Encarna; Castilla, Alberto; Castilla-Cortázar, Inma

2009-01-01

Cirrhosis is a diffuse process of hepatic fibrosis and regenerative nodule formation. The liver is the major source of circulating insulin-like growth factor-I (IGF-I) whose plasma levels are diminished in cirrhosis. IGF-I supplementation has been shown to induce beneficial effects in cirrhosis, including antifibrogenic and hepatoprotective effects. On other hand, interferon-alpha (IFN-alpha) therapy seems to suppress the progression of hepatic fibrosis. The aim of this study was to investigate the effect of the co-administration of IGF-I+IFN-alpha to Wistar rats with CCl(4)-induced cirrhosis, exploring liver function tests, hepatic lipid peroxidation and histopathology. The mechanisms underlying the effects of these agents were studied by reverse transcription-polymerase chain reaction, determining the expression of some factors [hepatocyte growth factor (HGF), transforming growth factor-beta (TGF-beta), alpha-smooth muscle actin, collagen, tissular inhibitor of metalloproteinases-1 and pregnane X receptor (PXR)] involved in fibrogenesis, fibrolysis and/or hepatoprotection. Both IGF-I and IFN-alpha exerted significant effects on fibrogenesis. IGF-I significantly increased serum albumin and HGF whereas IFN-alpha-therapy did not. The inhibition of TGF-beta expression was only observed by the effect of IFN-alpha-therapy. In addition, only the co-administration of IGF-I and IFN-alpha was able to increase the PXR. The combined therapy with both factors improved liver function tests, hepatic lipid peroxidation and reduced fibrosis, inducing a relevant histological improvement, reducing fibrosis and recovering hepatic architecture. The co-administration IGF-I+IFN enhanced all the beneficial effects observed with each factor separately, showing an additive action on histopathology and PXR expression, which is involved in the inhibition of fibrogenesis.

36 CFR 223.198 - Administrative remedies.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 36 Parks, Forests, and Public Property 2 2010-07-01 2010-07-01 false Administrative remedies. 223.198 Section 223.198 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE SALE... Act of 1990 Program § 223.198 Administrative remedies. In addition to possible debarment action...

42 CFR 405.1875 - Administrator review.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Appeals § 405.1875 Administrator review. (a) Basic rule: Time limit for rendering Administrator decisions... after the date the party making the request received the Board's decision or other reviewable action... decision or other reviewable matter. (ii) Any submission must be limited to the issues accepted for...

Faculty: Thy Administrator's Keeper? Some Evidence

ERIC Educational Resources Information Center

Cunningham, Brendan M.

2009-01-01

Colleges and universities face a principal-agent problem. There are information asymmetries over the actions chosen by administrators. Because non-profit constraints limit the financial stake of trustees there may be insufficient monitoring of administrators and, consequentially, shirking. It is conceivable that faculty will serve as "delegated…

[Therapeutic administration of immunoglobulins].

PubMed

Witte, T

2016-12-01

Intravenously administered immunoglobulins have multiple modes of action that are anti-inflammatory. They can therefore be beneficial in a number of autoimmune disorders. The aim of this article is to analyze and summarize studies on the administration of intravenous immunoglobulins in rheumatological diseases. A selective search and analysis of the literature was carried out related to the mode of action and efficacy of intravenous immunoglobulins in rheumatological diseases. Intravenous immunoglobulins have a broad mode of action and can therefore be beneficial in almost all autoimmune diseases. Conditions in which they are of special benefit include immunothrombopenia (ITP), Kawasaki disease and idiopathic inflammatory myopathies. In rare situations, they may also be indicated in systemic lupus erythematosus (SLE), Sjögren's syndrome and neuropathies, catastrophic antiphospholipid syndrome (APS), scleroderma, antineutrophil cytoplasmic antibody (ANCA) associated vasculitis, pyoderma gangrenosum and scleromyxedema. Severe adverse events are rare. In view of the high costs of the therapy, intravenous immunoglobulins are mostly applied in emergency situations, as salvage therapy when other standard therapies have failed or when severe infections are a contraindication to the administration of immunosuppressants.

40 CFR 264.302 - Action leakage rate.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Action leakage rate. 264.302 Section... § 264.302 Action leakage rate. (a) The Regional Administrator shall approve an action leakage rate for landfill units subject to § 264.301(c) or (d). The action leakage rate is the maximum design flow rate that...

14 CFR 1252.410 - Exhaustion of administrative remedies.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 5 2011-01-01 2010-01-01 true Exhaustion of administrative remedies. 1252..., Conciliation, and Enforcement Procedures § 1252.410 Exhaustion of administrative remedies. (a) A complainant may file a civil action following the exhaustion of administrative remedies under the Act...

42 CFR 8.32 - Administrative record.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 42 Public Health 1 2011-10-01 2011-10-01 false Administrative record. 8.32 Section 8.32 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS CERTIFICATION OF..., and of Adverse Action Regarding Withdrawal of Approval of an Accreditation Body § 8.32 Administrative...

42 CFR 8.32 - Administrative record.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 1 2010-10-01 2010-10-01 false Administrative record. 8.32 Section 8.32 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS CERTIFICATION OF..., and of Adverse Action Regarding Withdrawal of Approval of an Accreditation Body § 8.32 Administrative...

18 CFR 808.2 - Administrative appeals.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 18 Conservation of Power and Water Resources 2 2010-04-01 2010-04-01 false Administrative appeals. 808.2 Section 808.2 Conservation of Power and Water Resources SUSQUEHANNA RIVER BASIN COMMISSION HEARINGS AND ENFORCEMENT ACTIONS Conduct of Hearings § 808.2 Administrative appeals. (a) A project sponsor...

48 CFR 522.804 - Affirmative action programs.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 4 2011-10-01 2011-10-01 false Affirmative action programs. 522.804 Section 522.804 Federal Acquisition Regulations System GENERAL SERVICES ADMINISTRATION... Affirmative action programs. ...

48 CFR 522.804 - Affirmative action programs.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Affirmative action programs. 522.804 Section 522.804 Federal Acquisition Regulations System GENERAL SERVICES ADMINISTRATION... Affirmative action programs. ...

28 CFR 61.4 - Major federal action.

Code of Federal Regulations, 2010 CFR

2010-07-01

... ENVIRONMENTAL POLICY ACT General § 61.4 Major federal action. The NEPA regulations define “major federal action... judicial or administrative enforcement proceedings or civil or criminal litigation, including but not...

41 CFR 101-8.724 - Exhaustion of administrative remedies.

Code of Federal Regulations, 2011 CFR

2011-07-01

... administrative remedies. 101-8.724 Section 101-8.724 Public Contracts and Property Management Federal Property... Exhaustion of administrative remedies. (a) A complainant may file a civil action following the exhaustion of administrative remedies under the Act. Administrative remedies are exhausted if: (1) 180 calendar days elapse...

41 CFR 101-8.724 - Exhaustion of administrative remedies.

Code of Federal Regulations, 2010 CFR

2010-07-01

... administrative remedies. 101-8.724 Section 101-8.724 Public Contracts and Property Management Federal Property... Exhaustion of administrative remedies. (a) A complainant may file a civil action following the exhaustion of administrative remedies under the Act. Administrative remedies are exhausted if: (1) 180 calendar days elapse...

Affirmative Action Employment Plan. Revised.

ERIC Educational Resources Information Center

Oakland Unified School District, CA.

This is the affirmative action employment plan adopted by the Board of Education of the Oakland Unified School District, Oakland, California. A statement of school district policy and goals is provided. Responsibilities of the school district administrators and the Affirmative Action Advisory Committee are also outlined. Steps to be taken to…

76 FR 45332 - Pipeline and Hazardous Materials Safety Administration

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-28

... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration Office of... Hazardous Materials Safety Administration (PHMSA), DOT. ACTION: List of Applications for Modification of..., 2011. ADDRESSES: Record Center, Pipeline and Hazardous Materials Safety Administration, U.S. Department...

43 CFR 17.339 - Exhaustion of administrative remedies.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 43 Public Lands: Interior 1 2011-10-01 2011-10-01 false Exhaustion of administrative remedies. 17... Investigation, Conciliation, and Enforcement Procedures § 17.339 Exhaustion of administrative remedies. (a) A complainant may file a civil action following the exhaustion of administrative remedies under the Act...

45 CFR 91.50 - Exhaustion of administrative remedies.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 45 Public Welfare 1 2010-10-01 2010-10-01 false Exhaustion of administrative remedies. 91.50... Investigation, Conciliation, and Enforcement Procedures § 91.50 Exhaustion of administrative remedies. (a) A complainant may file a civil action following the exhaustion of administrative remedies under the Act...

45 CFR 91.50 - Exhaustion of administrative remedies.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 45 Public Welfare 1 2011-10-01 2011-10-01 false Exhaustion of administrative remedies. 91.50... Investigation, Conciliation, and Enforcement Procedures § 91.50 Exhaustion of administrative remedies. (a) A complainant may file a civil action following the exhaustion of administrative remedies under the Act...

45 CFR 1156.21 - Exhaustion of administrative remedies.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 45 Public Welfare 3 2010-10-01 2010-10-01 false Exhaustion of administrative remedies. 1156.21... Investigation, Conciliation, and Enforcement Procedures § 1156.21 Exhaustion of administrative remedies. (a) A complainant may file a civil action following the exhaustion of administrative remedies under the Act...

Student Voice in High School: An Action Research Study

ERIC Educational Resources Information Center

Termini, Lorraine

2013-01-01

This action research study examined the effects of student voice in one high school and the self-reflection of the researcher-administrator involved in the effort. Using three cycles of action research, the researcher-administrator completed a pilot study, implemented a student voice project in one class, and developed a professional development…

12 CFR 263.22 - Consolidation and severance of actions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Consolidation and severance of actions. (a) Consolidation. (1) On the motion of any party, or on the administrative law judge's own motion, the administrative law judge may consolidate, for some or all purposes... 12 Banks and Banking 3 2010-01-01 2010-01-01 false Consolidation and severance of actions. 263.22...

12 CFR 308.22 - Consolidation and severance of actions.

Code of Federal Regulations, 2011 CFR

2011-01-01

... severance of actions. (a) Consolidation. (1) On the motion of any party, or on the administrative law judge's own motion, the administrative law judge may consolidate, for some or all purposes, any two or... 12 Banks and Banking 4 2011-01-01 2011-01-01 false Consolidation and severance of actions. 308.22...

12 CFR 509.22 - Consolidation and severance of actions.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Consolidation and severance of actions. (a) Consolidation. (1) On the motion of any party, or on the administrative law judge's own motion, the administrative law judge may consolidate, for some or all purposes... 12 Banks and Banking 5 2011-01-01 2011-01-01 false Consolidation and severance of actions. 509.22...

76 FR 27002 - Information Collection; National Recreation Program Administration

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-10

... Administration AGENCY: Forest Service, USDA. ACTION: Notice; request for comment. SUMMARY: In accordance with the... organizations on the new information collection, National Recreation Program Administration. DATES: Comments... holidays. SUPPLEMENTARY INFORMATION: Title: National Recreation Program Administration. OMB Number: 0596...

75 FR 20364 - Public Buildings Service; Key Largo Beacon Annex Site; Key Largo, FL; Transfer of Property

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-19

... GENERAL SERVICES ADMINISTRATION [Wildlife Order 187; 4-D-FL-1218] Public Buildings Service; Key Largo Beacon Annex Site; Key Largo, FL; Transfer of Property Pursuant to section 2 of Public Law 537, 80th Congress, approved May 19, 1948 (16 U.S.C. 667c), notice is hereby given that: 1. The General...

Seven key actions to eradicate rheumatic heart disease in Africa: the Addis Ababa communiqué.

PubMed

Watkins, David; Zuhlke, Liesl; Engel, Mark; Daniels, Rezeen; Francis, Veronica; Shaboodien, Gasnat; Kango, Mabvuto; Abul-Fadl, Azza; Adeoye, Abiodun; Ali, Sulafa; Al-Kebsi, Mohammed; Bode-Thomas, Fidelia; Bukhman, Gene; Damasceno, Albertino; Goshu, Dejuma Yadeta; Elghamrawy, Alaa; Gitura, Bernard; Haileamlak, Abraham; Hailu, Abraha; Hugo-Hamman, Christopher; Justus, Steve; Karthikeyan, Ganesan; Kennedy, Neil; Lwabi, Peter; Mamo, Yoseph; Mntla, Pindile; Sutton, Chris; Mocumbi, Ana Olga; Mondo, Charles; Mtaja, Agnes; Musuku, John; Mucumbitsi, Joseph; Murango, Louis; Nel, George; Ogendo, Stephen; Ogola, Elijah; Ojji, Dike; Olunuga, Taiwo Olabisi; Redi, Mekia Mohammed; Rusingiza, Kamanzi Emmanuel; Sani, Mahmoud; Sheta, Sahar; Shongwe, Steven; van Dam, Joris; Gamra, Habib; Carapetis, Jonathan; Lennon, Diana; Mayosi, Bongani M

Acute rheumatic fever (ARF) and rheumatic heart disease (RHD) remain major causes of heart failure, stroke and death among African women and children, despite being preventable and imminently treatable. From 21 to 22 February 2015, the Social Cluster of the Africa Union Commission (AUC) hosted a consultation with RHD experts convened by the Pan-African Society of Cardiology (PASCAR) in Addis Ababa, Ethiopia, to develop a 'roadmap' of key actions that need to be taken by governments to eliminate ARF and eradicate RHD in Africa. Seven priority areas for action were adopted: (1) create prospective disease registers at sentinel sites in affected countries to measure disease burden and track progress towards the reduction of mortality by 25% by the year 2025, (2) ensure an adequate supply of high-quality benzathine penicillin for the primary and secondary prevention of ARF/RHD, (3) improve access to reproductive health services for women with RHD and other non-communicable diseases (NCD), (4) decentralise technical expertise and technology for diagnosing and managing ARF and RHD (including ultrasound of the heart), (5) establish national and regional centres of excellence for essential cardiac surgery for the treatment of affected patients and training of cardiovascular practitioners of the future, (6) initiate national multi-sectoral RHD programmes within NCD control programmes of affected countries, and (7) foster international partnerships with multinational organisations for resource mobilisation, monitoring and evaluation of the programme to end RHD in Africa. This Addis Ababa communiqué has since been endorsed by African Union heads of state, and plans are underway to implement the roadmap in order to end ARF and RHD in Africa in our lifetime.

25 CFR 700.479 - Administrative review.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false Administrative review. 700.479 Section 700.479 Indians... Discretionary Funds § 700.479 Administrative review. (a) If the Commissioners determine that implementation of... is terminated or suspended under paragraph (b) of this section may request a review of such action by...

23 CFR 140.605 - Approval actions.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 23 Highways 1 2014-04-01 2014-04-01 false Approval actions. 140.605 Section 140.605 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PAYMENT PROCEDURES REIMBURSEMENT Reimbursement for Bond Issue Projects § 140.605 Approval actions. (a) Authorization to proceed with preliminary...

23 CFR 140.605 - Approval actions.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 23 Highways 1 2013-04-01 2013-04-01 false Approval actions. 140.605 Section 140.605 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PAYMENT PROCEDURES REIMBURSEMENT Reimbursement for Bond Issue Projects § 140.605 Approval actions. (a) Authorization to proceed with preliminary...

23 CFR 140.605 - Approval actions.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 23 Highways 1 2011-04-01 2011-04-01 false Approval actions. 140.605 Section 140.605 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PAYMENT PROCEDURES REIMBURSEMENT Reimbursement for Bond Issue Projects § 140.605 Approval actions. (a) Authorization to proceed with preliminary...

23 CFR 140.605 - Approval actions.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 23 Highways 1 2010-04-01 2010-04-01 false Approval actions. 140.605 Section 140.605 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PAYMENT PROCEDURES REIMBURSEMENT Reimbursement for Bond Issue Projects § 140.605 Approval actions. (a) Authorization to proceed with preliminary...

78 FR 69288 - Import Administration; Change of Agency Name

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-19

...] RIN 0625-AA98 Import Administration; Change of Agency Name AGENCY: Foreign-Trade Zones Board, International Trade Administration, Commerce. ACTION: Final rule; nomenclature change. SUMMARY: Effective... orders, changed the name of ``Import Administration'' to ``Enforcement and Compliance.'' Consistent with...

40 CFR 7.175 - Exhaustion of administrative remedy.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Exhaustion of administrative remedy. 7... Discrimination Prohibited on the Basis of Age § 7.175 Exhaustion of administrative remedy. (a) A complainant may file a civil action following the exhaustion of administrative remedies under the Age Discrimination...

24 CFR 146.45 - Exhaustion of administrative remedies.

Code of Federal Regulations, 2011 CFR

2011-04-01

... remedies. 146.45 Section 146.45 Housing and Urban Development Regulations Relating to Housing and Urban... Exhaustion of administrative remedies. (a) A complainant may file a civil action following the exhaustion of administrative remedies under the Act. Administrative remedies are exhausted if: (1) 180 days have elapsed since...

40 CFR 7.175 - Exhaustion of administrative remedy.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Exhaustion of administrative remedy. 7... Discrimination Prohibited on the Basis of Age § 7.175 Exhaustion of administrative remedy. (a) A complainant may file a civil action following the exhaustion of administrative remedies under the Age Discrimination...

75 FR 53975 - Administration for Native Americans; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-02

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Administration for Children and Families Administration..., Administration for Children and Families. ACTION: Notice of Tribal Consultation. SUMMARY: The Department of Health and Human Services (HHS), Administration for Children and Families (ACF) will host a tribal...

14 CFR 161.415 - Reevaluation action.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Reevaluation action. 161.415 Section 161.415 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED... § 161.415 Reevaluation action. (a) Upon completing the reevaluation, the FAA will issue appropriate...

National Credit Union Administration Semiannual Regulatory Agenda

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-26

... only the minimum required burdens on credit unions, consumers, and the public; are appropriate for the... Administration--Completed Actions Regulation Sequence Title Identifier Number Number 412 Privacy of Consumer... Actions 412. PRIVACY OF CONSUMER FINANCIAL INFORMATION Legal Authority: 15 USC 6801 et seq Abstract: NCUA...

Insulin- like Growth Factor-Binding Protein Action in Bone Tissue: A Key Role for Pregnancy- Associated Plasma Protein-A.

PubMed

Beattie, James; Al-Khafaji, Hasanain; Noer, Pernille R; Alkharobi, Hanaa Esa; Alhodhodi, Aishah; Meade, Josephine; El-Gendy, Reem; Oxvig, Claus

2018-01-01

The insulin-like growth factor (IGF) axis is required for the differentiation, development, and maintenance of bone tissue. Accordingly, dysregulation of this axis is associated with various skeletal pathologies including growth abnormalities and compromised bone structure. It is becoming increasingly apparent that the action of the IGF axis must be viewed holistically taking into account not just the actions of the growth factors and receptors, but also the influence of soluble high affinity IGF binding proteins (IGFBPs).There is a recognition that IGFBPs exert IGF-dependent and IGF-independent effects in bone and other tissues and that an understanding of the mechanisms of action of IGFBPs and their regulation in the pericellular environment impact critically on tissue physiology. In this respect, a group of IGFBP proteinases (which may be considered as ancillary members of the IGF axis) play a crucial role in regulating IGFBP function. In this model, cleavage of IGFBPs by specific proteinases into fragments with lower affinity for growth factor(s) regulates the partition of IGFs between IGFBPs and cell surface IGF receptors. In this review, we examine the importance of IGFBP function in bone tissue with special emphasis on the role of pregnancy associated plasma protein-A (PAPP-A). We examine the function of PAPP-A primarily as an IGFBP-4 proteinase and present evidence that PAPP-A induced cleavage of IGFBP-4 is potentially a key regulatory step in bone metabolism. We also highlight some recent findings with regard to IGFBP-2 and IGFBP-5 (also PAPP-A substrates) function in bone tissue and briefly discuss the actions of the other three IGFBPs (-1, -3, and -6) in this tissue. Although our main focus will be in bone we will allude to IGFBP activity in other cells and tissues where appropriate.

40 CFR 265.302 - Action leakage rate.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Action leakage rate. 265.302 Section... FACILITIES Landfills § 265.302 Action leakage rate. (a) The owner or operator of landfill units subject to § 265.301(a) must submit a proposed action leakage rate to the Regional Administrator when submitting...

Novice Administrators: Psychological and Physiological Effects.

ERIC Educational Resources Information Center

Schmidt, Linda J.; Kosmoski, Georgia J.; Pollack, Dennis R.

Novice school administrators find that demands for excellence have grown while budgets have shrunk. This paper reports on a study that examined the stress levels of beginning administrators. Two of the key questions for the study--Is the stress experienced by new school administrators manageable or out of control? and Does the job put beginning…

75 FR 31744 - Information Collection; Contract Operations and Administration

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-04

... Administration AGENCY: Forest Service, USDA. ACTION: Notice; request for comment. SUMMARY: In accordance with the... organizations on a new information collection, Contract Operations and Administration. DATES: Comments must be... INFORMATION: Title: Contract Operations and Administration. OMB Number: 0596-NEW. Expiration Date of Approval...

77 FR 40069 - Single-Ingredient, Immediate-Release Drug Products Containing Oxycodone for Oral Administration...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-06

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2012-N-0563... Labeled for Human Use; Enforcement Action Dates AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA or Agency) is announcing its intention to take enforcement...

14 CFR 91.103 - Preflight action.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Preflight action. 91.103 Section 91.103 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIR TRAFFIC... action. Each pilot in command shall, before beginning a flight, become familiar with all available...

14 CFR 91.103 - Preflight action.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 2 2011-01-01 2011-01-01 false Preflight action. 91.103 Section 91.103 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIR TRAFFIC... action. Each pilot in command shall, before beginning a flight, become familiar with all available...

40 CFR 265.255 - Action leakage rates.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Action leakage rates. 265.255 Section... FACILITIES Waste Piles § 265.255 Action leakage rates. (a) The owner or operator of waste pile units subject to § 265.254 must submit a proposed action leakage rate to the Regional Administrator when submitting...

5 CFR 2636.104 - Civil, disciplinary and other action.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Civil, disciplinary and other action... Provisions § 2636.104 Civil, disciplinary and other action. (a) Civil action. Except when the employee... prohibited conduct, whichever is greater. (b) Disciplinary and corrective action. An agency may initiate...

28 CFR 104.61 - Limitation on civil actions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Limitation on civil actions. 104.61... COMPENSATION FUND OF 2001 Limitations § 104.61 Limitation on civil actions. (a) General. Section 405(c)(3)(B... to file a civil action (or be a party to an action) in any Federal or State court for damages...

28 CFR 104.61 - Limitation on civil actions.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Limitation on civil actions. 104.61... COMPENSATION FUND Limitations § 104.61 Limitation on civil actions. (a) General. Section 405(c)(3)(C) of the... a civil action (or be a party to an action) in any Federal or State court for damages sustained as a...

28 CFR 104.61 - Limitation on civil actions.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 28 Judicial Administration 2 2011-07-01 2011-07-01 false Limitation on civil actions. 104.61... COMPENSATION FUND OF 2001 Limitations § 104.61 Limitation on civil actions. (a) General. Section 405(c)(3)(B... to file a civil action (or be a party to an action) in any Federal or State court for damages...

12 CFR 1008.309 - Absence of liability for good-faith administration.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 12 Banks and Banking 8 2013-01-01 2013-01-01 false Absence of liability for good-faith... for Administration of the NMLSR § 1008.309 Absence of liability for good-faith administration. The... action or proceeding for monetary damages by reason of the good-faith action or omission of any officer...

12 CFR 1008.309 - Absence of liability for good-faith administration.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 12 Banks and Banking 8 2012-01-01 2012-01-01 false Absence of liability for good-faith... for Administration of the NMLSR § 1008.309 Absence of liability for good-faith administration. The... action or proceeding for monetary damages by reason of the good-faith action or omission of any officer...

12 CFR 1008.309 - Absence of liability for good-faith administration.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 12 Banks and Banking 8 2014-01-01 2014-01-01 false Absence of liability for good-faith... for Administration of the NMLSR § 1008.309 Absence of liability for good-faith administration. The... action or proceeding for monetary damages by reason of the good-faith action or omission of any officer...

Comparative synthesis and antimicrobial action of silver nanoparticles and silver nitrate

NASA Astrophysics Data System (ADS)

Mosselhy, Dina A.; El-Aziz, Mohamed Abd; Hanna, Magdy; Ahmed, Mohamed A.; Husien, Mona M.; Feng, Qingling

2015-12-01

The high wave of antibiotic bacterial resistance has addressed an importance for administration of different antibacterial agents, as silver nanoparticles (Ag NPs). However, many investigators still suffer conflict in the mechanistic antimicrobial action of Ag NPs and Ag+ ions. In this regard, our study investigated the comparative antimicrobial action of different sizes of Ag NPs as 8 (nAg1) and 29 (nAg2) nm, in comparison with silver nitrate (AgNO3) against five different bacterial species; Aeromonas hydrophila ( A. hydrophila), Pseudomonas putida ( Ps. putida), Escherichia coli ( E. coli), Staphylococcus aureus ( S. aureus), and Bacillus subtilis ( B. subtilis) using agar diffusion assay and minimum inhibitory concentration (MIC). The key role of the size of nanomaterials was detected, as the smaller Ag NPs (nAg1) showed more antimicrobial action than the larger particles. Transmission electron microscopy (TEM) studies demonstrated the different mechanistic antibacterial actions of Ag NPs and AgNO3. The effect of combining Ag NPs with antibiotics was also investigated. Synergistic effect of combining Ag NPs with ampicillin was detected against S. aureus, in a size-dependent manner as well. To summarize, our results point towards the major role played by the size of Ag NPs in their antimicrobial effects and the different toxic mechanisms of actions induced by Ag NPs and AgNO3.

77 FR 22358 - Occupational Safety and Health Administration

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-13

... DEPARTMENT OF LABOR Occupational Safety and Health Administration Preparations for the 23rd...: Occupational Safety and Health Administration (OSHA), Labor. ACTION: Notice of public meeting. SUMMARY: OSHA... health, physical, and environmental effects. It also provides harmonized communication elements...

76 FR 8400 - National Highway Traffic Safety Administration

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-14

... DEPARTMENT OF TRANSPORTATION National Highway Traffic Safety Administration Petition for Exemption From the Vehicle Theft Prevention Standard; Mitsubishi Motors AGENCY: National Highway Traffic Safety Administration (NHTSA) Department of Transportation (DOT). ACTION: Grant of petition for exemption. SUMMARY: This...

18 CFR 401.7 - Further action.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 18 Conservation of Power and Water Resources 2 2011-04-01 2011-04-01 false Further action. 401.7 Section 401.7 Conservation of Power and Water Resources DELAWARE RIVER BASIN COMMISSION ADMINISTRATIVE MANUAL RULES OF PRACTICE AND PROCEDURE Comprehensive Plan § 401.7 Further action. The Commission will...

18 CFR 401.7 - Further action.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 18 Conservation of Power and Water Resources 2 2010-04-01 2010-04-01 false Further action. 401.7 Section 401.7 Conservation of Power and Water Resources DELAWARE RIVER BASIN COMMISSION ADMINISTRATIVE MANUAL RULES OF PRACTICE AND PROCEDURE Comprehensive Plan § 401.7 Further action. The Commission will...

76 FR 30236 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-24

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2011-0061] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 31004 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-27

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2011-0069] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 18300 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-01

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket Number MARAD-2011 0031] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 24563 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-02

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD 2011 0040] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 28846 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-18

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD 2011 0055] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 31007 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-27

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2011-0066] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 55734 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-08

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2011-0014] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 55734 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-08

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2011-0012] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 24563 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-02

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD 2011 0042] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 6183 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-03

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2011 0001] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 26793 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-09

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD 2011 0041] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 28846 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-18

... DEPARTMENT OF TRANSPORTATION Maritime Administration Docket No. MARAD-2011-0052 Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 51467 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-18

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2011-0105] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 30237 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-24

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2011-0054] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 55733 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-08

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2011-0113] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 29332 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-20

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2011 0053] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 31007 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-27

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2011-0065] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 35943 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-20

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2011-0075] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 18299 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-01

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket Number MARAD 2011-0032] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 13701 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-14

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket Number MARAD-2011 0024] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 31006 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-27

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2011-0064] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 30755 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-26

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2011 0068] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 18299 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-01

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket Number MARAD 2011 0034] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

78 FR 14806 - Health Resources and Services Administration

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-07

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Health Resources and Services Administration Statement of Organization, Functions and Delegations of Authority; Correction AGENCY: Health Resources and Services Administration (HRSA), HHS. ACTION: Notice; correction. SUMMARY: HRSA published a document in the Federal...

77 FR 66910 - Notice of Final Federal Agency Actions on Proposed Highway in California

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-07

... DEPARTMENT OF TRANSPORTATION Federal Highway Administration Notice of Final Federal Agency Actions on Proposed Highway in California AGENCY: Federal Highway Administration (FHWA), DOT. ACTION: Notice...). A claim seeking judicial review of the Federal agency actions on the highway project will be barred...

Key issues and challenges in developing a pedagogical intervention in the simulation skills center--an action research study.

PubMed

Reierson, Inger Åse; Hvidsten, Anne; Wighus, Marianne; Brungot, Solvor; Bjørk, Ida Torunn

2013-07-01

Simulation skills centers (SSC) are considered important learning arenas for preparing and qualifying nursing students. Limited clinical placements and claims of diminished learning opportunities raise concerns that newly educated nurses lack proficiency in many psychomotor skills. Accordingly, there is an increased focus on learning in the SSC. However, it has been questioned if the pedagogical underpinning of teaching and learning in the SSC is missing or unclear. At a bachelor nursing education in Norway, there was a desire to change practice and enhance learning in the SSC by systematic use of The Model of Practical Skill Performance (Bjørk and Kirkevold, 2000). A participatory action research design was chosen. A pedagogical intervention was developed and implemented in 2010 in a cohort of eighty-seven first year bachelor nursing students during their basic nursing skill course. The intervention is shortly described. This article reports key issues and challenges that emerged during development of the new intervention. Data to inform the study were collected via thorough meeting minutes and the project leader's logbook, and analyzed using fieldnotes analysis. Six key issues and challenges were identified. These are presented and discussed consecutively in light of their importance for development and implementation of the new intervention. Copyright © 2013 Elsevier Ltd. All rights reserved.

32 CFR 1901.44 - Action by appeals authority.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 6 2013-07-01 2013-07-01 false Action by appeals authority. 1901.44 Section 1901.44 National Defense Other Regulations Relating to National Defense CENTRAL INTELLIGENCE AGENCY PUBLIC RIGHTS UNDER THE PRIVACY ACT OF 1974 Action on Privacy Act Administrative Appeals § 1901.44 Action...

32 CFR 1901.44 - Action by appeals authority.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 6 2011-07-01 2011-07-01 false Action by appeals authority. 1901.44 Section 1901.44 National Defense Other Regulations Relating to National Defense CENTRAL INTELLIGENCE AGENCY PUBLIC RIGHTS UNDER THE PRIVACY ACT OF 1974 Action on Privacy Act Administrative Appeals § 1901.44 Action...

28 CFR 42.724 - Remedial and affirmative action.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 28 Judicial Administration 1 2011-07-01 2011-07-01 false Remedial and affirmative action. 42.724... affirmative action. (a) If the Department finds that, in violation of this subpart, a recipient has discriminated on the basis of age, the recipient shall take remedial action that the Department considers...

28 CFR 42.724 - Remedial and affirmative action.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Remedial and affirmative action. 42.724... affirmative action. (a) If the Department finds that, in violation of this subpart, a recipient has discriminated on the basis of age, the recipient shall take remedial action that the Department considers...

78 FR 57445 - Charging Standard Administrative Fees for Nonprogram-Related Information

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-18

... SOCIAL SECURITY ADMINISTRATION [Docket No. SSA-2012-0026] Charging Standard Administrative Fees for Nonprogram-Related Information AGENCY: Social Security Administration. ACTION: Notice of standard... administration of a program under the Social Security Act (Act). SUPPLEMENTARY INFORMATION: Section 1106 of the...

Similar Cerebral Motor Plans for Real and Virtual Actions

PubMed Central

Bozzacchi, Chiara; Giusti, Maria Assunta; Pitzalis, Sabrina; Spinelli, Donatella; Di Russo, Francesco

2012-01-01

A simple movement, such as pressing a button, can acquire different meanings by producing different consequences, such as starting an elevator or switching a TV channel. We evaluated whether the brain activity preceding a simple action is modulated by the expected consequences of the action itself. To further this aim, the motor-related cortical potentials were compared during two key-press actions that were identical from the kinematics point of view but different in both meaning and consequences. In one case (virtual grasp), the key-press started a video clip showing a hand moving toward a cup and grasping it; in the other case, the key-press did not produce any consequence (key-press). A third condition (real grasp) was also compared, in which subjects actually grasped the cup, producing the same action presented in the video clip. Data were collected from fifteen subjects. The results showed that motor preparation for virtual grasp (starting 3 s before the movement onset) was different from that of the key-press and similar to the real grasp preparation–as if subjects had to grasp the cup in person. In particular, both virtual and real grasp presented a posterior parietal negativity preceding activity in motor and pre-motor areas. In summary, this finding supports the hypothesis that motor preparation is affected by the meaning of the action, even when the action is only virtual. PMID:23112847

Federal Aviation Administration : reauthorization provides opportunities to address key agency challenges

DOT National Transportation Integrated Search

2003-04-10

Much has changed since the Wendell H. Ford Aviation Investment and Reform Act for the 21st Century (AIR-21) reauthorized the Federal Aviation Administration's (FAA) programs 3 years ago. At that time, air traffic was increasing, and concerns about co...

29 CFR 1990.147 - Final action.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 29 Labor 9 2010-07-01 2010-07-01 false Final action. 1990.147 Section 1990.147 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED... Occupational Carcinogens § 1990.147 Final action. (a) Within one hundred twenty (120) days from the last day of...

10 CFR 1040.89-13 - Exhaustion of administrative remedies.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 4 2011-01-01 2011-01-01 false Exhaustion of administrative remedies. 1040.89-13 Section... Investigation, Conciliation and Enforcement Procedures § 1040.89-13 Exhaustion of administrative remedies. (a) A complainant may file a civil action following the exhaustion of administrative remedies under the Act...

10 CFR 1040.89-13 - Exhaustion of administrative remedies.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Exhaustion of administrative remedies. 1040.89-13 Section... Investigation, Conciliation and Enforcement Procedures § 1040.89-13 Exhaustion of administrative remedies. (a) A complainant may file a civil action following the exhaustion of administrative remedies under the Act...

42 CFR 456.407 - UR responsibilities of administrative staff.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 42 Public Health 4 2014-10-01 2014-10-01 false UR responsibilities of administrative staff. 456... administrative staff. The UR plan must describe— (a) The UR support responsibilities of the ICF's administrative staff; and (b) Procedures used by the staff for taking needed corrective action. UR Plan: Informational...

42 CFR 456.407 - UR responsibilities of administrative staff.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 42 Public Health 4 2012-10-01 2012-10-01 false UR responsibilities of administrative staff. 456... administrative staff. The UR plan must describe— (a) The UR support responsibilities of the ICF's administrative staff; and (b) Procedures used by the staff for taking needed corrective action. UR Plan: Informational...

42 CFR 456.407 - UR responsibilities of administrative staff.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 4 2010-10-01 2010-10-01 false UR responsibilities of administrative staff. 456... administrative staff. The UR plan must describe— (a) The UR support responsibilities of the ICF's administrative staff; and (b) Procedures used by the staff for taking needed corrective action. UR Plan: Informational...

42 CFR 456.407 - UR responsibilities of administrative staff.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 42 Public Health 4 2013-10-01 2013-10-01 false UR responsibilities of administrative staff. 456... administrative staff. The UR plan must describe— (a) The UR support responsibilities of the ICF's administrative staff; and (b) Procedures used by the staff for taking needed corrective action. UR Plan: Informational...

42 CFR 456.407 - UR responsibilities of administrative staff.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 42 Public Health 4 2011-10-01 2011-10-01 false UR responsibilities of administrative staff. 456... administrative staff. The UR plan must describe— (a) The UR support responsibilities of the ICF's administrative staff; and (b) Procedures used by the staff for taking needed corrective action. UR Plan: Informational...

40 CFR 35.6815 - Administrative requirements.

Code of Federal Regulations, 2014 CFR

2014-07-01

... ASSISTANCE STATE AND LOCAL ASSISTANCE Cooperative Agreements and Superfund State Contracts for Superfund Response Actions Requirements for Administering A Superfund State Contract (ssc) § 35.6815 Administrative...

40 CFR 35.6815 - Administrative requirements.

Code of Federal Regulations, 2010 CFR

2010-07-01

... ASSISTANCE STATE AND LOCAL ASSISTANCE Cooperative Agreements and Superfund State Contracts for Superfund Response Actions Requirements for Administering A Superfund State Contract (ssc) § 35.6815 Administrative...

40 CFR 35.6815 - Administrative requirements.

Code of Federal Regulations, 2013 CFR

2013-07-01

... ASSISTANCE STATE AND LOCAL ASSISTANCE Cooperative Agreements and Superfund State Contracts for Superfund Response Actions Requirements for Administering A Superfund State Contract (ssc) § 35.6815 Administrative...

40 CFR 35.6815 - Administrative requirements.

Code of Federal Regulations, 2011 CFR

2011-07-01

... ASSISTANCE STATE AND LOCAL ASSISTANCE Cooperative Agreements and Superfund State Contracts for Superfund Response Actions Requirements for Administering A Superfund State Contract (ssc) § 35.6815 Administrative...

40 CFR 35.6815 - Administrative requirements.

Code of Federal Regulations, 2012 CFR

2012-07-01

... ASSISTANCE STATE AND LOCAL ASSISTANCE Cooperative Agreements and Superfund State Contracts for Superfund Response Actions Requirements for Administering A Superfund State Contract (ssc) § 35.6815 Administrative...

76 FR 9853 - Notice of Final Federal Agency Actions on Proposed Highway in California

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-22

... DEPARTMENT OF TRANSPORTATION Federal Highway Administration Notice of Final Federal Agency Actions on Proposed Highway in California AGENCY: Federal Highway Administration (FHWA), DOT. ACTION: Notice... final within the meaning of 23 U.S.C. 139(l)(1). The actions relate to a proposed highway project...

Corrective Action Decision Document for Corrective Action Unit 204: Storage Bunkers, Nevada Test Site, Nevada: Revision 0, Including Errata Sheet

DOE Office of Scientific and Technical Information (OSTI.GOV)

U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office

2004-04-01

This Corrective Action Decision Document identifies the U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office's corrective action alternative recommendation for each of the corrective action sites (CASs) within Corrective Action Unit (CAU) 204: Storage Bunkers, Nevada Test Site (NTS), Nevada, under the Federal Facility Agreement and Consent Order. An evaluation of analytical data from the corrective action investigation, review of current and future operations at each CAS, and a detailed comparative analysis of potential corrective action alternatives were used to determine the appropriate corrective action for each CAS. There are six CASs in CAU 204, which aremore » all located between Areas 1, 2, 3, and 5 on the NTS. The No Further Action alternative was recommended for CASs 01-34-01, 02-34-01, 03-34-01, and 05-99-02; and a Closure in Place with Administrative Controls recommendation was the preferred corrective action for CASs 05-18-02 and 05-33-01. These alternatives were judged to meet all requirements for the technical components evaluated as well as applicable state and federal regulations for closure of the sites and will eliminate potential future exposure pathways to the contaminated media at CAU 204.« less

77 FR 64794 - Membership of the Economic Development Administration Performance Review Board

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-23

... DEPARTMENT OF COMMERCE Economic Development Administration Membership of the Economic Development Administration Performance Review Board AGENCY: Economic Development Administration, Department of Commerce. ACTION: Notice of Membership on the Economic Development Administration's Performance Review Board...

75 FR 63813 - Membership of the Economic Development Administration Performance Review Board

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-18

... DEPARTMENT OF COMMERCE Economic Development Administration Membership of the Economic Development Administration Performance Review Board AGENCY: Economic Development Administration, Department of Commerce. ACTION: Notice of membership on the Economic Development Administration's Performance Review Board...

21 CFR 812.30 - FDA action on applications.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 8 2012-04-01 2012-04-01 false FDA action on applications. 812.30 Section 812.30...) MEDICAL DEVICES INVESTIGATIONAL DEVICE EXEMPTIONS Application and Administrative Action § 812.30 FDA action on applications. (a) Approval or disapproval. FDA will notify the sponsor in writing of the date...

21 CFR 812.30 - FDA action on applications.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 8 2011-04-01 2011-04-01 false FDA action on applications. 812.30 Section 812.30...) MEDICAL DEVICES INVESTIGATIONAL DEVICE EXEMPTIONS Application and Administrative Action § 812.30 FDA action on applications. (a) Approval or disapproval. FDA will notify the sponsor in writing of the date...

21 CFR 812.30 - FDA action on applications.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 8 2014-04-01 2014-04-01 false FDA action on applications. 812.30 Section 812.30...) MEDICAL DEVICES INVESTIGATIONAL DEVICE EXEMPTIONS Application and Administrative Action § 812.30 FDA action on applications. (a) Approval or disapproval. FDA will notify the sponsor in writing of the date...

21 CFR 812.30 - FDA action on applications.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 8 2013-04-01 2013-04-01 false FDA action on applications. 812.30 Section 812.30...) MEDICAL DEVICES INVESTIGATIONAL DEVICE EXEMPTIONS Application and Administrative Action § 812.30 FDA action on applications. (a) Approval or disapproval. FDA will notify the sponsor in writing of the date...

21 CFR 812.30 - FDA action on applications.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 8 2010-04-01 2010-04-01 false FDA action on applications. 812.30 Section 812.30...) MEDICAL DEVICES INVESTIGATIONAL DEVICE EXEMPTIONS Application and Administrative Action § 812.30 FDA action on applications. (a) Approval or disapproval. FDA will notify the sponsor in writing of the date...

49 CFR 222.57 - Can parties seek review of the Associate Administrator's actions?

Code of Federal Regulations, 2010 CFR

2010-10-01

..., the State agency responsible for grade crossing safety, the State agency responsible for highway and road safety, and the Associate Administrator. Unless the Administrator specifically provides otherwise... additional safety measures, by filing a petition for reconsideration with the Associate Administrator. The...

49 CFR 222.57 - Can parties seek review of the Associate Administrator's actions?

Code of Federal Regulations, 2011 CFR

2011-10-01

..., the State agency responsible for grade crossing safety, the State agency responsible for highway and road safety, and the Associate Administrator. Unless the Administrator specifically provides otherwise... additional safety measures, by filing a petition for reconsideration with the Associate Administrator. The...

9 CFR 4.10 - Summary action.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Summary action. 4.10 Section 4.10 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL... Practice § 4.10 Summary action. (a) In any situation where the Administrator has reason to believe that any...

44 CFR 7.949 - Exhaustion of administrative remedies.

Code of Federal Regulations, 2011 CFR

2011-10-01

... remedies. 7.949 Section 7.949 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY... Investigation, Conciliation, and Enforcement Procedures § 7.949 Exhaustion of administrative remedies. (a) A complainant may file a civil action following the exhaustion of administrative remedies under the Act...

44 CFR 7.949 - Exhaustion of administrative remedies.

Code of Federal Regulations, 2010 CFR

2010-10-01

... remedies. 7.949 Section 7.949 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY... Investigation, Conciliation, and Enforcement Procedures § 7.949 Exhaustion of administrative remedies. (a) A complainant may file a civil action following the exhaustion of administrative remedies under the Act...

Extending experiences of voluntary action by association

PubMed Central

Khalighinejad, Nima; Haggard, Patrick

2016-01-01

“Sense of agency” refers to the experience that links one’s voluntary actions to their external outcomes. It remains unclear whether this ubiquitous experience is hardwired, arising from specific signals within the brain’s motor systems, or rather depends on associative learning, through repeated cooccurrence of voluntary movements and their outcomes. To distinguish these two models, we asked participants to trigger a tone by a voluntary keypress action. The voluntary action was always associated with an involuntary movement of the other hand. We then tested whether the combination of the involuntary movement and tone alone might now suffice to produce a sense of agency, even when the voluntary action was omitted. Sense of agency was measured using an implicit marker based on time perception, namely a shift in the perceived time of the outcome toward the action that caused it. Across two experiments, repeatedly pairing an involuntary movement with a voluntary action induced key temporal features of agency, with the outcome now perceived as shifted toward the involuntary movement. This shift required involuntary movements to have been previously associated with voluntary actions. We show that some key aspects of agency may be transferred from voluntary actions to involuntary movements. An internal volitional signal is required for the primary acquisition of agency but, with repeated association, the involuntary movement in itself comes to produce some key temporal features of agency over the subsequent outcome. This finding may explain how humans can develop an enduring sense of agency in nonnatural cases, like brain–machine interfaces. PMID:27436902

Time for action: key considerations for implementing social accountability in the education of health professionals.

PubMed

Ventres, William; Boelen, Charles; Haq, Cynthia

2017-09-12

Within health professional education around the world, there exists a growing awareness of the professional duty to be socially responsible, being attentive to the needs of all members of communities, regions, and nations, especially those who disproportionately suffer from the adverse influence of social determinants. However, much work still remains to progress beyond such good intentions. Moving from contemplation to action means embracing social accountability as a key guiding principle for change. Social accountability means that health institutions attend to improving the performance of individual practitioners and health systems by directing educational and practice interventions to promote the health of all the public and assessing the systemic effects of these interventions. In this Reflection, the authors (1) review the reasons why health professional schools and their governing bodies should codify, in both curricular and accreditation standards, norms of excellence in social accountability, (2) present four considerations crucial to successfully implementing this codification, and (3) discuss the challenges such changes might entail. The authors conclude by noting that in adopting socially accountable criteria, schools will need to expand their philosophical scope to recognize social accountability as a vitally important part of their institutional professional identity.

78 FR 64595 - Notice of Final Federal Agency Actions on Proposed Highway in Illinois

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-29

... DEPARTMENT OF TRANSPORTATION Federal Highway Administration Notice of Final Federal Agency Actions on Proposed Highway in Illinois AGENCY: Federal Highway Administration (FHWA), DOT. ACTION: Notice of... Sec. 139(l)(1). The actions relate to a proposed highway project, Circle Interchange, I-90/I-94 and I...

Corrective Action Decision Document/Closure Report for Corrective Action Unit 567: Miscellaneous Soil Sites - Nevada National Security Site, Nevada

DOE Office of Scientific and Technical Information (OSTI.GOV)

Matthews, Patrick

2014-12-01

This Corrective Action Decision Document/Closure Report presents information supporting the closure of Corrective Action Unit (CAU) 567: Miscellaneous Soil Sites, Nevada National Security Site, Nevada. The purpose of this Corrective Action Decision Document/Closure Report is to provide justification and documentation supporting the recommendation that no further corrective action is needed for CAU 567 based on the implementation of the corrective actions. The corrective actions implemented at CAU 567 were developed based on an evaluation of analytical data from the CAI, the assumed presence of COCs at specific locations, and the detailed and comparative analysis of the CAAs. The CAAs weremore » selected on technical merit focusing on performance, reliability, feasibility, safety, and cost. The implemented corrective actions meet all requirements for the technical components evaluated. The CAAs meet all applicable federal and state regulations for closure of the site. Based on the implementation of these corrective actions, the DOE, National Nuclear Security Administration Nevada Field Office provides the following recommendations: • No further corrective actions are necessary for CAU 567. • The Nevada Division of Environmental Protection issue a Notice of Completion to the DOE, National Nuclear Security Administration Nevada Field Office for closure of CAU 567. • CAU 567 be moved from Appendix III to Appendix IV of the FFACO.« less

40 CFR 300.800 - Establishment of an administrative record.

Code of Federal Regulations, 2011 CFR

2011-07-01

... POLLUTION CONTINGENCY PLAN Administrative Record for Selection of Response Action § 300.800 Establishment of... agency for a federal facility. (3) If EPA is involved in the selection of the response action at a... record that contains the documents that form the basis for the selection of a response action. The lead...

40 CFR 300.800 - Establishment of an administrative record.

Code of Federal Regulations, 2010 CFR

2010-07-01

... POLLUTION CONTINGENCY PLAN Administrative Record for Selection of Response Action § 300.800 Establishment of... agency for a federal facility. (3) If EPA is involved in the selection of the response action at a... record that contains the documents that form the basis for the selection of a response action. The lead...

40 CFR 300.800 - Establishment of an administrative record.

Code of Federal Regulations, 2014 CFR

2014-07-01

... POLLUTION CONTINGENCY PLAN Administrative Record for Selection of Response Action § 300.800 Establishment of... agency for a federal facility. (3) If EPA is involved in the selection of the response action at a... record that contains the documents that form the basis for the selection of a response action. The lead...

40 CFR 300.800 - Establishment of an administrative record.

Code of Federal Regulations, 2012 CFR

2012-07-01

... POLLUTION CONTINGENCY PLAN Administrative Record for Selection of Response Action § 300.800 Establishment of... agency for a federal facility. (3) If EPA is involved in the selection of the response action at a... record that contains the documents that form the basis for the selection of a response action. The lead...

40 CFR 300.800 - Establishment of an administrative record.

Code of Federal Regulations, 2013 CFR

2013-07-01

... POLLUTION CONTINGENCY PLAN Administrative Record for Selection of Response Action § 300.800 Establishment of... agency for a federal facility. (3) If EPA is involved in the selection of the response action at a... record that contains the documents that form the basis for the selection of a response action. The lead...

Hierarchical pulmonary target nanoparticles via inhaled administration for anticancer drug delivery.

PubMed

Chen, Rui; Xu, Liu; Fan, Qin; Li, Man; Wang, Jingjing; Wu, Li; Li, Weidong; Duan, Jinao; Chen, Zhipeng

2017-11-01

Inhalation administration, compared with intravenous administration, significantly enhances chemotherapeutic drug exposure to the lung tissue and may increase the therapeutic effect for pulmonary anticancer. However, further identification of cancer cells after lung deposition of inhaled drugs is necessary to avoid side effects on normal lung tissue and to maximize drug efficacy. Moreover, as the action site of the major drug was intracellular organelles, drug target to the specific organelle is the final key for accurate drug delivery. Here, we designed a novel multifunctional nanoparticles (MNPs) for pulmonary antitumor and the material was well-designed for hierarchical target involved lung tissue target, cancer cell target, and mitochondrial target. The biodistribution in vivo determined by UHPLC-MS/MS method was employed to verify the drug concentration overwhelmingly increasing in lung tissue through inhaled administration compared with intravenous administration. Cellular uptake assay using A549 cells proved the efficient receptor-mediated cell endocytosis. Confocal laser scanning microscopy observation showed the location of MNPs in cells was mitochondria. All results confirmed the intelligent material can progressively play hierarchical target functions, which could induce more cell apoptosis related to mitochondrial damage. It provides a smart and efficient nanocarrier platform for hierarchical targeting of pulmonary anticancer drug. So far, this kind of material for pulmonary mitochondrial-target has not been seen in other reports.

Survey of Key Concepts in Enactivist Theory and Methodology

ERIC Educational Resources Information Center

Reid, David A.; Mgombelo, Joyce

2015-01-01

This article discusses key concepts within enactivist writing, focussing especially on concepts involved in the enactivist description of cognition as embodied action: perceptually guided action, embodiment, and structural coupling through recurrent sensorimotor patterns. Other concepts on which these concepts depend are also discussed, including…

Quality in Action: Closing the Loop

ERIC Educational Resources Information Center

Nair, Chenicheri Sid; Pawley, David; Mertova, Patricie

2010-01-01

Purpose: This paper aims to report on how an Administrative Division at a research-intensive Australian university utilised feedback data from the Learning and Growth Survey, to initiate changes. Design/methodology/approach: This paper refers to the actions taken by the Administrative Division to the results obtained from the Learning and Growth…

76 FR 55928 - Food and Drug Administration Health Professional Organizations Conference

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-09

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2011-N-0002] Food and Drug Administration Health Professional Organizations Conference AGENCY: Food and Drug Administration, HHS. ACTION: Notice of public conference. The Food and Drug Administration (FDA) is announcing a...

49 CFR 1503.607 - Administrative law judges.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 9 2012-10-01 2012-10-01 false Administrative law judges. 1503.607 Section 1503... PROCEDURES Rules of Practice in TSA Civil Penalty Actions § 1503.607 Administrative law judges. (a) Powers of...) Administer oaths and affirmations. (4) Issue subpoenas authorized by law. (5) Rule on offers of proof. (6...

49 CFR 1503.607 - Administrative law judges.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 9 2010-10-01 2010-10-01 false Administrative law judges. 1503.607 Section 1503... PROCEDURES Rules of Practice in TSA Civil Penalty Actions § 1503.607 Administrative law judges. (a) Powers of...) Administer oaths and affirmations. (4) Issue subpoenas authorized by law. (5) Rule on offers of proof. (6...

Affirmative Action Guidelines.

ERIC Educational Resources Information Center

Barbarita, Juana

Clarifying guidelines are presented for use by California community college districts in interpreting Title 5 of the California Administrative Code, which requires the adoption of employee affirmative action plans, including goals and timetables to increase the number of ethnic minorities and women in district employment. Following material on the…

78 FR 67210 - Charging Standard Administrative Fees for Nonprogram-Related Information; Correction

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-08

... SOCIAL SECURITY ADMINISTRATION [Docket No. SSA-2012-0026] Charging Standard Administrative Fees for Nonprogram-Related Information; Correction AGENCY: Social Security Administration. ACTION: Notice... Social Security Administration published a document in the Federal Register of September 18, 2013...

Setting objectives for managing Key deer

USGS Publications Warehouse

Diefenbach, Duane R.; Wagner, Tyler; Stauffer, Glenn E.

2014-01-01

The U.S. Fish and Wildlife Service (FWS) is responsible for the protection and management of Key deer (Odocoileus virginianus clavium) because the species is listed as Endangered under the Endangered Species Act (ESA). The purpose of the ESA is to protect and recover imperiled species and the ecosystems upon which they depend. There are a host of actions that could possibly be undertaken to recover the Key deer population, but without a clearly defined problem and stated objectives it can be difficult to compare and evaluate alternative actions. In addition, management goals and the acceptability of alternative management actions are inherently linked to stakeholders, who should be engaged throughout the process of developing a decision framework. The purpose of this project was to engage a representative group of stakeholders to develop a problem statement that captured the management problem the FWS must address with Key deer and identify objectives that, if met, would help solve the problem. In addition, the objectives were organized in a hierarchical manner (i.e., an objectives network) to show how they are linked, and measurable attributes were identified for each objective. We organized a group of people who represented stakeholders interested in and potentially affected by the management of Key deer. These stakeholders included individuals who represented local, state, and federal governments, non-governmental organizations, the general public, and local businesses. This stakeholder group met five full days over the course of an eight-week period to identify objectives that would address the following problem:“As recovery and removal from the Endangered Species list is the purpose of the Endangered Species Act, the U.S. Fish and Wildlife Service needs a management approach that will ensure a sustainable, viable, and healthy Key deer population. Urbanization has affected the behavior and population dynamics of the Key deer and the amount and characteristics

7 CFR 246.18 - Administrative review of State agency actions.

Code of Federal Regulations, 2011 CFR

2011-01-01

...) The State agency's determination to include or exclude an infant formula manufacturer, wholesaler... WOMEN, INFANTS AND CHILDREN State Agency Provisions § 246.18 Administrative review of State agency...

5 CFR 1201.136 - Action on stay request.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 5 Administrative Personnel 3 2011-01-01 2011-01-01 false Action on stay request. 1201.136 Section....136 Action on stay request. (a) Initial stay. A Special Counsel request for an initial stay of 45 days... extending a stay, the agency ordered to stay a personnel action must file evidence setting forth facts and...

44 CFR 10.12 - Pre-implementation actions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Pre-implementation actions. (a) Decision-making. The Regional Administrator shall ensure that... integrated into the decision-making process. Because of the diversity of FEMA, it is not feasible to describe in this part the decision-making process for each of the various FEMA programs. Proposals and actions...

Knowledge Producing, Its Management and Action and Action Research

ERIC Educational Resources Information Center

Hadfield, Mark

2005-01-01

This article is based on a "think piece" produced as a resource for action researchers working within networks of schools. The original article considered the utility of key ideas within knowledge management to practitioner researchers attempting to share their research outcomes with other teachers in their network. This article, rather than…

75 FR 42481 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-21

... Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, DOT. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws for the vessel SEAFLYER... Administration (MARAD), is authorized to grant waivers of the U.S.-build requirement of the coastwise laws under...

45 CFR 91.50 - Exhaustion of administrative remedies.

Code of Federal Regulations, 2013 CFR

2013-10-01

... her right to bring a civil action for injunctive relief; and (3) Inform the complainant: (i) That the... recipient is found or transacts business; (ii) That a complainant prevailing in a civil action has the right... Section 91.50 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION...

45 CFR 91.50 - Exhaustion of administrative remedies.

Code of Federal Regulations, 2012 CFR

2012-10-01

... her right to bring a civil action for injunctive relief; and (3) Inform the complainant: (i) That the... recipient is found or transacts business; (ii) That a complainant prevailing in a civil action has the right... Section 91.50 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION...

12 CFR 747.22 - Consolidation and severance of actions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... ADMINISTRATIVE ACTIONS, ADJUDICATIVE HEARINGS, RULES OF PRACTICE AND PROCEDURE, AND INVESTIGATIONS Uniform Rules... the motion of any party, or on the administrative law judge's own motion, the administrative law judge... involves at least one common respondent or a material common question of law or fact, unless such...

5 CFR 1305.5 - No private right of action.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false No private right of action. 1305.5 Section 1305.5 Administrative Personnel OFFICE OF MANAGEMENT AND BUDGET ADMINISTRATIVE PROCEDURES RELEASE OF OFFICIAL INFORMATION, AND TESTIMONY BY OMB PERSONNEL AS WITNESSES, IN LITIGATION § 1305.5 No...

5 CFR 315.605 - Appointment of former ACTION volunteers.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 5 Administrative Personnel 1 2014-01-01 2014-01-01 false Appointment of former ACTION volunteers... Authorities § 315.605 Appointment of former ACTION volunteers. (a) Agency authority. An agency in the... Director of ACTION certifies as having served satisfactorily as a volunteer or volunteer leader under the...

5 CFR 315.605 - Appointment of former ACTION volunteers.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 5 Administrative Personnel 1 2011-01-01 2011-01-01 false Appointment of former ACTION volunteers... Authorities § 315.605 Appointment of former ACTION volunteers. (a) Agency authority. An agency in the... Director of ACTION certifies as having served satisfactorily as a volunteer or volunteer leader under the...

5 CFR 315.605 - Appointment of former ACTION volunteers.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 5 Administrative Personnel 1 2012-01-01 2012-01-01 false Appointment of former ACTION volunteers... Authorities § 315.605 Appointment of former ACTION volunteers. (a) Agency authority. An agency in the... Director of ACTION certifies as having served satisfactorily as a volunteer or volunteer leader under the...

5 CFR 315.605 - Appointment of former ACTION volunteers.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 5 Administrative Personnel 1 2013-01-01 2013-01-01 false Appointment of former ACTION volunteers... Authorities § 315.605 Appointment of former ACTION volunteers. (a) Agency authority. An agency in the... Director of ACTION certifies as having served satisfactorily as a volunteer or volunteer leader under the...

5 CFR 315.605 - Appointment of former ACTION volunteers.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Appointment of former ACTION volunteers... Authorities § 315.605 Appointment of former ACTION volunteers. (a) Agency authority. An agency in the... Director of ACTION certifies as having served satisfactorily as a volunteer or volunteer leader under the...

12 CFR 747.22 - Consolidation and severance of actions.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 12 Banks and Banking 6 2011-01-01 2011-01-01 false Consolidation and severance of actions. 747.22... ADMINISTRATIVE ACTIONS, ADJUDICATIVE HEARINGS, RULES OF PRACTICE AND PROCEDURE, AND INVESTIGATIONS Uniform Rules of Practice and Procedure § 747.22 Consolidation and severance of actions. (a) Consolidation. (1) On...

Immune-Mediated Mechanisms of Action of Probiotics and Synbiotics in Treating Pediatric Intestinal Diseases

PubMed Central

Gil-Campos, Mercedes

2018-01-01

The pediatric population is continually at risk of developing infectious and inflammatory diseases. The treatment for infections, particularly gastrointestinal conditions, focuses on oral or intravenous rehydration, nutritional support and, in certain case, antibiotics. Over the past decade, the probiotics and synbiotics administration for the prevention and treatment of different acute and chronic infectious diseases has dramatically increased. Probiotic microorganisms are primarily used as treatments because they can stimulate changes in the intestinal microbial ecosystem and improve the immunological status of the host. The beneficial impact of probiotics is mediated by different mechanisms. These mechanisms include the probiotics’ capacity to increase the intestinal barrier function, to prevent bacterial transferation and to modulate inflammation through immune receptor cascade signaling, as well as their ability to regulate the expression of selected host intestinal genes. Nevertheless, with respect to pediatric intestinal diseases, information pertaining to these key mechanisms of action is scarce, particularly for immune-mediated mechanisms of action. In the present work, we review the biochemical and molecular mechanisms of action of probiotics and synbiotics that affect the immune system. PMID:29303974

14 CFR 13.231 - Argument before the administrative law judge.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Argument before the administrative law... Actions § 13.231 Argument before the administrative law judge. (a) Arguments during the hearing. During the hearing, the administrative law judge shall give the parties a reasonable opportunity to present...

14 CFR 13.231 - Argument before the administrative law judge.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Argument before the administrative law... Actions § 13.231 Argument before the administrative law judge. (a) Arguments during the hearing. During the hearing, the administrative law judge shall give the parties a reasonable opportunity to present...

Action Research and Academic Writing: A Conversation

ERIC Educational Resources Information Center

Winter, Richard; Badley, Graham

2007-01-01

Here is a conversation between two former colleagues about action research and academic writing. Richard Winter opens the discussion with a series of reflections on his work as an action researcher. These reflections include the key argument that action research is a noble cause because it is relevant to working life, has a practical impact and…

40 CFR 35.110 - Time frame for EPA action.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 1 2012-07-01 2012-07-01 false Time frame for EPA action. 35.110... ASSISTANCE STATE AND LOCAL ASSISTANCE Environmental Program Grants Epa Action on Application § 35.110 Time frame for EPA action. The Regional Administrator will review a complete application and either approve...

42 CFR 93.406 - Final HHS actions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... MISCONDUCT Responsibilities of the U.S. Department of Health and Human Services Research Misconduct Issues... prescribed in § 93.501, the ORI finding of research misconduct is the final HHS action on the research misconduct issues and the HHS administrative actions become final and will be implemented, except that the...

75 FR 71412 - Notice of Public Meeting of the Committee on Administration

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-23

... ADMINISTRATIVE CONFERENCE OF THE UNITED STATES Notice of Public Meeting of the Committee on Administration AGENCY: Administrative Conference of the United States. ACTION: Notice of meeting. SUMMARY: Notice is hereby given that the Administrative Conference of the United States will host a public meeting of...

45 CFR 77.3 - Conditions that may give rise to remedial actions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 45 Public Welfare 1 2011-10-01 2011-10-01 false Conditions that may give rise to remedial actions. 77.3 Section 77.3 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION REMEDIAL ACTIONS APPLICABLE TO LETTER OF CREDIT ADMINISTRATION § 77.3 Conditions that may give rise to...