Sample records for key component technologies

  1. Component improvement of free-piston Stirling engine key technology for space power

    NASA Technical Reports Server (NTRS)

    Alger, Donald L.

    1988-01-01

    The successful performance of the 25 kW Space Power Demonstrator (SPD) engine during an extensive testing period has provided a baseline of free piston Stirling engine technology from which future space Stirling engines may evolve. Much of the success of the engine was due to the initial careful selection of engine materials, fabrication and joining processes, and inspection procedures. Resolution of the few SPD engine problem areas that did occur has resulted in the technological advancement of certain key free piston Stirling engine components. Derivation of two half-SPD, single piston engines from the axially opposed piston SPD engine, designated as Space Power Research (SPR) engines, has made possible the continued improvement of these engine components. The two SPR engines serve as test bed engines for testing of engine components. Some important fabrication and joining processes are reviewed. Also, some component deficiencies that were discovered during SPD engine testing are described and approaches that were taken to correct these deficiencies are discussed. Potential component design modifications, based upon the SPD and SPR engine testing, are also reported.

  2. Development of a Novel Brayton-Cycle Cryocooler and Key Component Technologies

    NASA Astrophysics Data System (ADS)

    Nieczkoski, S. J.; Mohling, R. A.

    2004-06-01

    Brayton-cycle cryocoolers are being developed to provide efficient cooling in the 6 K to 70 K temperature range. The cryocoolers are being developed for use in space and in terrestrial applications where combinations of long lifetime, high efficiency, compactness, low mass, low vibration, flexible interfacing, load variability, and reliability are essential. The key enabling technologies for these systems are a mesoscale expander and an advanced oil-free scroll compressor. Both these components are nearing completion of their prototype development phase. The emphasis on the component and system development has been on invoking fabrication processes and techniques that can be evolved to further reduction in scale tending toward cryocooler miniaturization.

  3. Electric vehicle recycling 2020: Key component power electronics.

    PubMed

    Bulach, Winfried; Schüler, Doris; Sellin, Guido; Elwert, Tobias; Schmid, Dieter; Goldmann, Daniel; Buchert, Matthias; Kammer, Ulrich

    2018-04-01

    Electromobility will play a key role in order to reach the specified ambitious greenhouse gas reduction targets in the German transport sector of 42% between 1990 and 2030. Subsequently, a significant rise in the sale of electric vehicles (EVs) is to be anticipated in future. The amount of EVs to be recycled will rise correspondingly after a delay. This includes the recyclable power electronics modules which are incorporated in every EV as an important component for energy management. Current recycling methods using car shredders and subsequent post shredder technologies show high recycling rates for the bulk metals but are still associated with high losses of precious and strategic metals such as gold, silver, platinum, palladium and tantalum. For this reason, the project 'Electric vehicle recycling 2020 - key component power electronics' developed an optimised recycling route for recycling power electronics modules from EVs which is also practicable in series production and can be implemented using standardised technology. This 'WEEE recycling route' involves the disassembly of the power electronics from the vehicle and a subsequent recycling in an electronic end-of-life equipment recycling plant. The developed recycling process is economical under the current conditions and raw material prices, even though it involves considerably higher costs than recycling using the car shredder. The life cycle assessment shows basically good results, both for the traditional car shredder route and the developed WEEE recycling route: the latter provides additional benefits from some higher recovery rates and corresponding credits.

  4. Security of quantum key distribution with multiphoton components

    PubMed Central

    Yin, Hua-Lei; Fu, Yao; Mao, Yingqiu; Chen, Zeng-Bing

    2016-01-01

    Most qubit-based quantum key distribution (QKD) protocols extract the secure key merely from single-photon component of the attenuated lasers. However, with the Scarani-Acin-Ribordy-Gisin 2004 (SARG04) QKD protocol, the unconditionally secure key can be extracted from the two-photon component by modifying the classical post-processing procedure in the BB84 protocol. Employing the merits of SARG04 QKD protocol and six-state preparation, one can extract secure key from the components of single photon up to four photons. In this paper, we provide the exact relations between the secure key rate and the bit error rate in a six-state SARG04 protocol with single-photon, two-photon, three-photon, and four-photon sources. By restricting the mutual information between the phase error and bit error, we obtain a higher secure bit error rate threshold of the multiphoton components than previous works. Besides, we compare the performances of the six-state SARG04 with other prepare-and-measure QKD protocols using decoy states. PMID:27383014

  5. Key participants in codeveloped technology pose for group picture

    NASA Technical Reports Server (NTRS)

    1997-01-01

    Following the presentation of the Universal Signal Conditioning Amplifier (USCA), a new piece of technology developed through a National Aeronautics and Space Administration (NASA) partnership with industry, to Kennedy Space Center (KSC) Director Roy Bridges, Jr., key participants in the partnership pose for a group portrait. They are (from left) Bill Larson, NASA; Dr. Pedro Medelius, INET; Roy Bridges, Jr., KSC Director; Ed Gladney and William Saputo, L-3 Communications; Pam Gillespi, representing Congressman Dave Weldon; and Frank Kinney, Technological Research and Development Authority. The USCA is a key component of the codeveloped Automated Data Acquisition System (ADAS) that measures temperature, pressure and vibration at KSC's launch pads. The breakthrough technology is expected to reduce sensor setup and configuration times from hours to seconds. KSC teamed up with Florida's Technological Research and Development Authority and manufacturer L-3 Communications to produce a system that would benefit the aerospace industry and other commercial markets.

  6. Key components of financial-analysis education for clinical nurses.

    PubMed

    Lim, Ji Young; Noh, Wonjung

    2015-09-01

    In this study, we identified key components of financial-analysis education for clinical nurses. We used a literature review, focus group discussions, and a content validity index survey to develop key components of financial-analysis education. First, a wide range of references were reviewed, and 55 financial-analysis education components were gathered. Second, two focus group discussions were performed; the participants were 11 nurses who had worked for more than 3 years in a hospital, and nine components were agreed upon. Third, 12 professionals, including professors, nurse executive, nurse managers, and an accountant, participated in the content validity index. Finally, six key components of financial-analysis education were selected. These key components were as follows: understanding the need for financial analysis, introduction to financial analysis, reading and implementing balance sheets, reading and implementing income statements, understanding the concepts of financial ratios, and interpretation and practice of financial ratio analysis. The results of this study will be used to develop an education program to increase financial-management competency among clinical nurses. © 2015 Wiley Publishing Asia Pty Ltd.

  7. High Cost/High Risk Components to Chalcogenide Molded Lens Model: Molding Preforms and Mold Technology

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bernacki, Bruce E.

    2012-10-05

    This brief report contains a critique of two key components of FiveFocal's cost model for glass compression molding of chalcogenide lenses for infrared applications. Molding preforms and mold technology have the greatest influence on the ultimate cost of the product and help determine the volumes needed to select glass molding over conventional single-point diamond turning or grinding and polishing. This brief report highlights key areas of both technologies with recommendations for further study.

  8. Component technology for stirling power converters

    NASA Technical Reports Server (NTRS)

    Thieme, Lanny G.

    1991-01-01

    NASA Lewis Research Center has organized a component technology program as part of the efforts to develop Stirling converter technology for space power applications. The Stirling Space Power Program is part of the NASA High Capacity Power Project of the Civil Space Technology Initiative (CSTI). NASA Lewis is also providing technical management for the DOE/Sandia program to develop Stirling converters for solar terrestrial power producing electricity for the utility grid. The primary contractors for the space power and solar terrestrial programs develop component technologies directly related to their goals. This Lewis component technology effort, while coordinated with the main programs, aims at longer term issues, advanced technologies, and independent assessments. An overview of work on linear alternators, engine/alternator/load interactions and controls, heat exchangers, materials, life and reliability, and bearings is presented.

  9. Key optical components for spaceborne lasers

    NASA Astrophysics Data System (ADS)

    Löhring, J.; Winzen, M.; Faidel, H.; Miesner, J.; Plum, D.; Klein, J.; Fitzau, O.; Giesberts, M.; Brandenburg, W.; Seidel, A.; Schwanen, N.; Riesters, D.; Hengesbach, S.; Hoffmann, H.-D.

    2016-03-01

    Spaceborne lidar (light detection and ranging) systems have a large potential to become powerful instruments in the field of atmospheric research. Obviously, they have to be in operation for about three years without any maintenance like readjusting. Furthermore, they have to withstand strong temperature cycles typically in the range of -30 to +50 °C as well as mechanical shocks and vibrations, especially during launch. Additionally, the avoidance of any organic material inside the laser box is required, particularly in UV lasers. For atmospheric research pulses of about several 10 mJ at repetition rates of several 10 Hz are required in many cases. Those parameters are typically addressed by DPSSL that comprise components like: laser crystals, nonlinear crystals in pockels cells, faraday isolators and frequency converters, passive fibers, diode lasers and of course a lot of mirrors and lenses. In particular, some components have strong requirements regarding their tilt stability that is often in the 10 μrad range. In most of the cases components and packages that are used for industrial lasers do not fulfil all those requirements. Thus, the packaging of all these key components has been developed to meet those specifications only making use of metal and ceramics beside the optical component itself. All joints between the optical component and the laser baseplate are soldered or screwed. No clamps or adhesives are used. Most of the critical properties like tilting after temperature cycling have been proven in several tests. Currently, these components are used to build up first prototypes for spaceborne systems.

  10. WRKY Transcription Factors: Key Components in Abscisic Acid Signaling

    DTIC Science & Technology

    2011-01-01

    Review article WRKY transcription factors : key components in abscisic acid signalling Deena L. Rushton1, Prateek Tripathi1, Roel C. Rabara1, Jun Lin1...May 2011. *Correspondence (Tel +605 688 5749; fax +605 688 5624; email paul.rushton@sdstate.edu) Keywords: abscisic acid, WRKY transcription factor ...seed germination, drought, abiotic stress. Summary WRKY transcription factors (TFs) are key regulators of many plant processes, including the responses

  11. Key Components in eHealth Interventions Combining Self-Tracking and Persuasive eCoaching to Promote a Healthier Lifestyle: A Scoping Review

    PubMed Central

    Oldenhuis, Hilbrand KE; de Groot, Martijn; Polstra, Louis; Velthuijsen, Hugo; van Gemert-Pijnen, Julia EWC

    2017-01-01

    Background The combination of self-tracking and persuasive eCoaching in automated interventions is a new and promising approach for healthy lifestyle management. Objective The aim of this study was to identify key components of self-tracking and persuasive eCoaching in automated healthy lifestyle interventions that contribute to their effectiveness on health outcomes, usability, and adherence. A secondary aim was to identify the way in which these key components should be designed to contribute to improved health outcomes, usability, and adherence. Methods The scoping review methodology proposed by Arskey and O’Malley was applied. Scopus, EMBASE, PsycINFO, and PubMed were searched for publications dated from January 1, 2013 to January 31, 2016 that included (1) self-tracking, (2) persuasive eCoaching, and (3) healthy lifestyle intervention. Results The search resulted in 32 publications, 17 of which provided results regarding the effect on health outcomes, 27 of which provided results regarding usability, and 13 of which provided results regarding adherence. Among the 32 publications, 27 described an intervention. The most commonly applied persuasive eCoaching components in the described interventions were personalization (n=24), suggestion (n=19), goal-setting (n=17), simulation (n=17), and reminders (n=15). As for self-tracking components, most interventions utilized an accelerometer to measure steps (n=11). Furthermore, the medium through which the user could access the intervention was usually a mobile phone (n=10). The following key components and their specific design seem to influence both health outcomes and usability in a positive way: reduction by setting short-term goals to eventually reach long-term goals, personalization of goals, praise messages, reminders to input self-tracking data into the technology, use of validity-tested devices, integration of self-tracking and persuasive eCoaching, and provision of face-to-face instructions during

  12. Advanced Key Technologies for Hot Control Surfaces in Space Re- Entry Vehicles

    NASA Astrophysics Data System (ADS)

    Dogigli, Michael; Pradier, Alain; Tumino, Giorgio

    2002-01-01

    (1)MAN Technologie AG, D- 86153 Augsburg, Germany (2,3) ESA, 2200 Noordwijk ZH, The Netherlands Current space re-entry vehicles (e.g. X-38 vehicle 201, the prototype of the International Space Station's Crew Return Vehicle (CRV)) require advanced control surfaces (so called body flaps). Such control surfaces allow the design of smaller and lighter vehicles as well as faster re-entries (compared to the US Shuttle). They are designed as light-weight structures that need no metallic parts, need no mass or volume consuming heat sinks to protect critical components (e.g. bearings) and that can be operated at temperatures of more than 1600 "C in air transferring high mechanical loads (dynamic 40 kN, static 70 kN) at the same time. Because there is a need for CRV and also for Reusable Launch Vehicles (RLV) in future, the European Space Agency (ESA) felt compelled to establish a "Future European Space Transportation and Investigation Program,, (FESTIP) and a "General Support for Technology Program,, (GSTP). One of the main goals of these programs was to develop and qualify key-technologies that are able to master the above mentioned challenging requirements for advanced hot control surfaces and that can be applied for different vehicles. In 1996 MAN Technologie has started the development of hot control surfaces for small lifting bodies in the national program "Heiü Strukturen,,. One of the main results of this program was that especially the following CMC (Ceramic Matrix Composite) key technologies need to be brought up to space flight standard: Complex CMC Structures, CMC Bearings, Metal-to-CMC Joining Technologies, CMC Fasteners, Oxidation Protection Systems and Static and Dynamic Seals. MAN Technologie was contracted by ESA to continue the development and qualification of these key technologies in the frame of the FESTIP and the GSTP program. Development and qualification have successfully been carried out. The key technologies have been applied for the X-38 vehicle

  13. Key Components in eHealth Interventions Combining Self-Tracking and Persuasive eCoaching to Promote a Healthier Lifestyle: A Scoping Review.

    PubMed

    Lentferink, Aniek J; Oldenhuis, Hilbrand Ke; de Groot, Martijn; Polstra, Louis; Velthuijsen, Hugo; van Gemert-Pijnen, Julia Ewc

    2017-08-01

    The combination of self-tracking and persuasive eCoaching in automated interventions is a new and promising approach for healthy lifestyle management. The aim of this study was to identify key components of self-tracking and persuasive eCoaching in automated healthy lifestyle interventions that contribute to their effectiveness on health outcomes, usability, and adherence. A secondary aim was to identify the way in which these key components should be designed to contribute to improved health outcomes, usability, and adherence. The scoping review methodology proposed by Arskey and O'Malley was applied. Scopus, EMBASE, PsycINFO, and PubMed were searched for publications dated from January 1, 2013 to January 31, 2016 that included (1) self-tracking, (2) persuasive eCoaching, and (3) healthy lifestyle intervention. The search resulted in 32 publications, 17 of which provided results regarding the effect on health outcomes, 27 of which provided results regarding usability, and 13 of which provided results regarding adherence. Among the 32 publications, 27 described an intervention. The most commonly applied persuasive eCoaching components in the described interventions were personalization (n=24), suggestion (n=19), goal-setting (n=17), simulation (n=17), and reminders (n=15). As for self-tracking components, most interventions utilized an accelerometer to measure steps (n=11). Furthermore, the medium through which the user could access the intervention was usually a mobile phone (n=10). The following key components and their specific design seem to influence both health outcomes and usability in a positive way: reduction by setting short-term goals to eventually reach long-term goals, personalization of goals, praise messages, reminders to input self-tracking data into the technology, use of validity-tested devices, integration of self-tracking and persuasive eCoaching, and provision of face-to-face instructions during implementation. In addition, health outcomes or

  14. Evolving Systems and Adaptive Key Component Control

    NASA Technical Reports Server (NTRS)

    Frost, Susan A.; Balas, Mark J.

    2009-01-01

    We propose a new framework called Evolving Systems to describe the self-assembly, or autonomous assembly, of actively controlled dynamical subsystems into an Evolved System with a higher purpose. An introduction to Evolving Systems and exploration of the essential topics of the control and stability properties of Evolving Systems is provided. This chapter defines a framework for Evolving Systems, develops theory and control solutions for fundamental characteristics of Evolving Systems, and provides illustrative examples of Evolving Systems and their control with adaptive key component controllers.

  15. Childhood Immunization: A Key Component of Early Childhood Development

    ERIC Educational Resources Information Center

    Messonnier, Nancy

    2017-01-01

    Physical health is a key component of early childhood development and school readiness. By keeping children healthy and decreasing the chances of disease outbreaks, immunizations help early childhood programs create a safe environment for children. While overall vaccination rates are high nationally for most vaccines routinely recommended for…

  16. Analysis of key technologies for virtual instruments metrology

    NASA Astrophysics Data System (ADS)

    Liu, Guixiong; Xu, Qingui; Gao, Furong; Guan, Qiuju; Fang, Qiang

    2008-12-01

    Virtual instruments (VIs) require metrological verification when applied as measuring instruments. Owing to the software-centered architecture, metrological evaluation of VIs includes two aspects: measurement functions and software characteristics. Complexity of software imposes difficulties on metrological testing of VIs. Key approaches and technologies for metrology evaluation of virtual instruments are investigated and analyzed in this paper. The principal issue is evaluation of measurement uncertainty. The nature and regularity of measurement uncertainty caused by software and algorithms can be evaluated by modeling, simulation, analysis, testing and statistics with support of powerful computing capability of PC. Another concern is evaluation of software features like correctness, reliability, stability, security and real-time of VIs. Technologies from software engineering, software testing and computer security domain can be used for these purposes. For example, a variety of black-box testing, white-box testing and modeling approaches can be used to evaluate the reliability of modules, components, applications and the whole VI software. The security of a VI can be assessed by methods like vulnerability scanning and penetration analysis. In order to facilitate metrology institutions to perform metrological verification of VIs efficiently, an automatic metrological tool for the above validation is essential. Based on technologies of numerical simulation, software testing and system benchmarking, a framework for the automatic tool is proposed in this paper. Investigation on implementation of existing automatic tools that perform calculation of measurement uncertainty, software testing and security assessment demonstrates the feasibility of the automatic framework advanced.

  17. Introduction to the Portable Life Support Schematic and Technology Development Components

    NASA Technical Reports Server (NTRS)

    Conger, Bruce

    2008-01-01

    Conger presented the operations and functions of the baseline Constellation Program (CxP) Portable Life Support System (PLSS) schematic and key development technologies. He explained the functional descriptions of the schematic components in the fluid systems of the PLSS for multiple operational scenarios. PLSS subsystems include the oxygen subsystem, the ventilation subsystem, and the thermal subsystem. He also presented the operational PLSS modes: Nominal EVA mode, Umbilical - no recharge mode, Umbilical - with recharge mode, BENDS mode, BUDDY mode, Secondary oxygen mode, and the PLSS-removed umbilical mode.

  18. Input from Key Stakeholders in the National Security Technology Incubator

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    This report documents the input from key stakeholders of the National Security Technology Incubator (NSTI) in developing a new technology incubator and related programs for southern New Mexico. The technology incubator is being developed as part of the National Security Preparedness Project (NSPP), funded by a Department of Energy (DOE)/National Nuclear Security Administration (NNSA) grant. This report includes identification of key stakeholders as well as a description and analysis of their input for the development of an incubator.

  19. Key Problems in Science and Technology in Thailand.

    ERIC Educational Resources Information Center

    Yuthavong, Yongyuth; And Others

    1985-01-01

    Cites the need for promoting science/technology management and policy formation in Thailand, viewing contributions of science/technology to the socioeconomic development of the country as high priorities. Criteria for selecting priority areas and key problems are noted; they include relevance to development, availability of human resources, and…

  20. Patient-Centred Care in Canada: Key Components and the Path Forward.

    PubMed

    Montague, Terrence; Gogovor, Amédé; Aylen, John; Ashley, Lisa; Ahmed, Sara; Martin, Lesli; Cochrane, Bonnie; Adams, Owen; Nemis-White, Joanna

    2017-01-01

    Canadians' health and its care continue to evolve. Chronic diseases affect more than 50% of our aging population, but the majority of public and professional stakeholders retain a sense of care quality. An emergent issue, however, is generating an increasingly wide debate. It is the concept of patient-centred care, including its definition of key components, and efficacy. To advance the evidence base, the 2013-2014 and 2016 Health Care in Canada (HCIC) surveys measured pan-stakeholder levels of support and implementation priorities for frequently proposed components of patient centricity in healthcare. The public's highest rated component was timely access to care, followed by perceived respect and caring in its delivery, with decisions made in partnership among patients and professional providers, and within a basic belief that care should be based on patients' needs versus their ability to pay. Health professionals' levels of support for key components largely overlapped the public's levels of support for key components, with an additional accent on care influenced by an evidence base and expert opinion. In terms of priority to actually implement enhanced patient-centred care options, timely access was universally dominant among all stakeholders. Caring, respectful care, also retained high implementation priority among both the public and professionals, as did care decisions made in partnership, and, among professionals, care driven by research and expert opinion. Low priorities, for both the public and professionals, were the actual measurements of patient-centred care delivery and its impact on outcomes. In summary, there is remarkable concordance among all stakeholders in terms of favoured interventions to enhance patient-centred care, namely, timely access, caring, partnering and communicative delivery of evidence-based care. Unfortunately, the lack of contemporary imperative around the value of measuring and reporting actual use and outcomes of favoured

  1. Software Component Technologies and Space Applications

    NASA Technical Reports Server (NTRS)

    Batory, Don

    1995-01-01

    In the near future, software systems will be more reconfigurable than hardware. This will be possible through the advent of software component technologies which have been prototyped in universities and research labs. In this paper, we outline the foundations for those technologies and suggest how they might impact software for space applications.

  2. Anomaly Monitoring Method for Key Components of Satellite

    PubMed Central

    Fan, Linjun; Xiao, Weidong; Tang, Jun

    2014-01-01

    This paper presented a fault diagnosis method for key components of satellite, called Anomaly Monitoring Method (AMM), which is made up of state estimation based on Multivariate State Estimation Techniques (MSET) and anomaly detection based on Sequential Probability Ratio Test (SPRT). On the basis of analysis failure of lithium-ion batteries (LIBs), we divided the failure of LIBs into internal failure, external failure, and thermal runaway and selected electrolyte resistance (R e) and the charge transfer resistance (R ct) as the key parameters of state estimation. Then, through the actual in-orbit telemetry data of the key parameters of LIBs, we obtained the actual residual value (R X) and healthy residual value (R L) of LIBs based on the state estimation of MSET, and then, through the residual values (R X and R L) of LIBs, we detected the anomaly states based on the anomaly detection of SPRT. Lastly, we conducted an example of AMM for LIBs, and, according to the results of AMM, we validated the feasibility and effectiveness of AMM by comparing it with the results of threshold detective method (TDM). PMID:24587703

  3. Legislation on violence against women: overview of key components.

    PubMed

    Ortiz-Barreda, Gaby; Vives-Cases, Carmen

    2013-01-01

    This study aimed to determine if legislation on violence against women (VAW) worldwide contains key components recommended by the Pan American Health Organization (PAHO) and the United Nations (UN) to help strengthen VAW prevention and provide better integrated victim protection, support, and care. A systematic search for VAW legislation using international legal databases and other electronic sources plus data from previous research identified 124 countries/territories with some type of VAW legislation. Full legal texts were found for legislation from 104 countries/territories. Those available in English, Portuguese, and Spanish were downloaded and compiled and the selection criteria applied (use of any of the common terms related to VAW, including intimate partner violence (IPV), and reference to at least two of six sectors (education, health, judicial system, mass media, police, and social services) with regard to VAW interventions (protection, support, and care). A final sample from 80 countries/territories was selected and analyzed for the presence of key components recommended by PAHO and the UN (reference to the term "violence against women" in the title; definitions of different types of VAW; identification of women as beneficiaries; and promotion of (reference to) the participation of multiple sectors in VAW interventions). Few countries/territories specifically identified women as the beneficiaries of their VAW legislation, including those that labeled their legislation "domestic violence" law ( n = 51), of which only two explicitly mentioned women as complainants/survivors. Only 28 countries/territories defined the main forms of VAW (economic, physical, psychological, and sexual) in their VAW legislation. Most highlighted the role of the judicial system, followed by that of social services and the police. Only 28 mentioned the health sector. Despite considerable efforts worldwide to strengthen VAW legislation, most VAW laws do not incorporate the key

  4. Small Engine Component Technology (SECT) studies

    NASA Technical Reports Server (NTRS)

    Meyer, P. K.; Harbour, L.

    1986-01-01

    A study was conducted to identify component technology requirements for small, expendable gas turbine engines that would result in substantial improvements in performance and cost by the year 2000. A subsonic, 2600 nautical mile (4815 km) strategic cruise missile mission was selected for study. A baseline (state-of-the-art) engine and missile configuration were defined to evaluate the advanced technology engines. Two advanced technology engines were configured and evaluated using advanced component efficiencies and ceramic composite materials; a 22:1 overall pressure ratio, 3.85 bypass ratio twin-spool turbofan; and an 8:1 overall pressure, 3.66 bypass ratio, single-spool recuperated turbofan with 0.85 recuperator effectiveness. Results of mission analysis indicated a reduction in fuel burn of 38 and 47 percent compared to the baseline engine when using the advanced turbofan and recuperated turbofan, respectively. While use of either advanced engine resulted in approximately a 25 percent reduction in missile size, the unit life cycle (LCC) cost reduction of 56 percent for the advanced turbofan relative to the baseline engine gave it a decisive advantage over the recuperated turbofan with 47 percent LCC reduction. An additional range improvement of 10 percent results when using a 56 percent loaded carbon slurry fuel with either engine. These results can be realized only if significant progress is attained in the fields of solid lubricated bearings, small aerodynamic component performance, composite ceramic materials and integration of slurry fuels. A technology plan outlining prospective programs in these fields is presented.

  5. Key Health Information Technologies and Related Issues for Iran: A Qualitative Study.

    PubMed

    Hemmat, Morteza; Ayatollahi, Haleh; Maleki, Mohammadreza; Saghafi, Fatemeh

    2018-01-01

    Planning for the future of Health Information Technology (HIT) requires applying a systematic approach when conducting foresight studies. The aim of this study was to identify key health information technologies and related issues for Iran until 2025. This was a qualitative study and the participants included experts and policy makers in the field of health information technology. In-depth semi-structured interviews were conducted and data were analyzed by using framework analysis and MAXQDA software. The findings revealed that the development of national health information network, electronic health records, patient health records, a cloud-based service center, interoperability standards, patient monitoring technologies, telehealth, mhealth, clinical decision support systems, health information technology and mhealth infrastructure were found to be the key technologies for the future. These technologies could influence the economic, organizational and individual levels. To achieve them, the economic and organizational obstacles need to be overcome. In this study, a number of key technologies and related issues were identified. This approach can help to focus on the most important technologies in the future and to priorities these technologies for better resource allocation and policy making.

  6. Key Health Information Technologies and Related Issues for Iran: A Qualitative Study

    PubMed Central

    Hemmat, Morteza; Ayatollahi, Haleh; Maleki, Mohammadreza; Saghafi, Fatemeh

    2018-01-01

    Background and Objective: Planning for the future of Health Information Technology (HIT) requires applying a systematic approach when conducting foresight studies. The aim of this study was to identify key health information technologies and related issues for Iran until 2025. Methods: This was a qualitative study and the participants included experts and policy makers in the field of health information technology. In-depth semi-structured interviews were conducted and data were analyzed by using framework analysis and MAXQDA software. Results: The findings revealed that the development of national health information network, electronic health records, patient health records, a cloud-based service center, interoperability standards, patient monitoring technologies, telehealth, mhealth, clinical decision support systems, health information technology and mhealth infrastructure were found to be the key technologies for the future. These technologies could influence the economic, organizational and individual levels. To achieve them, the economic and organizational obstacles need to be overcome. Conclusion: In this study, a number of key technologies and related issues were identified. This approach can help to focus on the most important technologies in the future and to priorities these technologies for better resource allocation and policy making. PMID:29854016

  7. Special Education Law: Illustrative Basics and Nuances of Key IDEA Components

    ERIC Educational Resources Information Center

    Zirkel, Perry A.

    2015-01-01

    Intended as professional development for both new and experienced special educators, this article provides both the basic requirements and nuanced issues for foundational, successive, and overlapping key components under the Individuals With Disabilities Education Act (IDEA): (a) child find, (b) eligibility, and (c) free appropriate public…

  8. Research on Key Technology and Applications for Internet of Things

    NASA Astrophysics Data System (ADS)

    Chen, Xian-Yi; Jin, Zhi-Gang

    The Internet of Things (IOT) has been paid more and more attention by the academe, industry, and government all over the world. The concept of IOT and the architecture of IOT are discussed. The key technologies of IOT, including Radio Frequency Identification technology, Electronic Product Code technology, and ZigBee technology are analyzed. The framework of digital agriculture application based on IOT is proposed.

  9. Research on the architecture and key technologies of SIG

    NASA Astrophysics Data System (ADS)

    Fu, Zhongliang; Meng, Qingxiang; Huang, Yan; Liu, Shufan

    2007-06-01

    Along with the development of computer network, Grid has become one of the hottest issues of researches on sharing and cooperation of Internet resources throughout the world. This paper illustrates a new architecture of SIG-a five-hierarchy architecture (including Data Collecting Layer, Grid Layer, Service Layer, Application Layer and Client Layer) of SIG from the traditional three hierarchies (only including resource layer, service layer and client layer). In the paper, the author proposes a new mixed network mode of Spatial Information Grid which integrates CAG (Certificate Authority of Grid) and P2P (Peer to Peer) in the Grid Layer, besides, the author discusses some key technologies of SIG and analysis the functions of these key technologies.

  10. Key technology issues for space robotic systems

    NASA Technical Reports Server (NTRS)

    Schappell, Roger T.

    1987-01-01

    Robotics has become a key technology consideration for the Space Station project to enable enhanced crew productivity and to maximize safety. There are many robotic functions currently being studied, including Space Station assembly, repair, and maintenance as well as satellite refurbishment, repair, and retrieval. Another area of concern is that of providing ground based experimenters with a natural interface that they might directly interact with their hardware onboard the Space Station or ancillary spacecraft. The state of the technology is such that the above functions are feasible; however, considerable development work is required for operation in this gravity-free vacuum environment. Furthermore, a program plan is evolving within NASA that will capitalize on recent government, university, and industrial robotics research and development (R and D) accomplishments. A brief summary is presented of the primary technology issues and physical examples are provided of the state of the technology for the initial operational capability (IOC) system as well as for the eventual final operational capability (FOC) Space Station.

  11. SMART-1: key technologies and autonomy implementations

    NASA Astrophysics Data System (ADS)

    Elfving, A.; Stagnaro, L.; Winton, A.

    2003-01-01

    SMART-1 is the first of the Small Missions for Advanced Research in Technology of the ESA Horizons 2000 Science Plan. The main mission objective of SMART-1 is to demonstrate innovative and key technologies for scientific deep-space missions. One of the key technologies is the solar electric propulsion used as primary propulsion. The electric propulsion will be using 1400 W to transfer the 350 kg spacecraft from an Ariane 5 standard GTO to an elliptic Moon polar orbit, 10000×300 km. The total mission time is 24 months including a maximum of 18 months transfer time. The spacecraft development entered the detailed design and implementation phase in October 1999, under the responsibility of the Swedish Space Cooperation as prime contractor, and the flight acceptance is targeted for the 3rd quarter of 2002. The committed total life cost budget is 84 million Euro. Apart from the in-orbit demonstration of electric propulsion as primary propulsion, SMART-1 is implementing many other enabling technologies for deep-space missions such as deep-space transponder with communication in X-band for uplink and in X- and Ka-band for downlink, highly integrated and radiation tolerant microprocessors, FPGAs and memories, high on-board autonomy driven by ground communication only once per 4 days, maximum available power to electric propulsion by centralised and software-controlled power management, minimum propellant consumption through innovative angular momentum management. In addition, the spacecraft avionics design is tailored to the low-cost philosophy by enabling flexible integration of commercial off the shelf (COTS) equipment. The scientific instruments, five in total, support characterisation of the electric propulsion thrust environment during the long transfer phase and detailed imaging and spectroscopy of the lunar surface in visible, infrared and X-ray during the Moon orbiting phase. Several of the instruments implement new enabling technologies, e.g. swept charge devices

  12. The strategic research agenda of the Technology Platform Photonics21: European component industry for broadband communications and the FP 7

    NASA Astrophysics Data System (ADS)

    Thylén, Lars

    2006-07-01

    The design and manufacture of components and systems underpin the European and indeed worldwide photonics industry. Optical materials and photonic components serve as the basis for systems building at different levels of complexity. In most cases, they perform a key function and dictate the performance of these systems. New products and processes will generate economic activity for the European photonics industry into the 21 st century. However, progress will rely on Europe's ability to develop new and better materials, components and systems. To achieve success, photonic components and systems must: •be reliable and inexpensive •be generic and adaptable •offer superior functionality •be innovative and protected by Intellectual Property •be aligned to market opportunities The challenge in the short-, medium-, and long-term is to put a coordinating framework in place which will make the European activity in this technology area competitive as compared to those in the US and Asia. In the short term the aim should be to facilitate the vibrant and profitable European photonics industry to further develop its ability to commercialize advances in photonic related technologies. In the medium and longer terms the objective must be to place renewed emphasis on materials research and the design and manufacturing of key components and systems to form the critical link between science endeavour and commercial success. All these general issues are highly relevant for the component intensive broadband communications industry. Also relevant for this development is the convergence of data and telecom, where the low cost of data com meets with the high reliability requirements of telecom. The text below is to a degree taken form the Strategic Research Agenda of the Technology Platform Photonics 21 [1], as this contains a concerted effort to iron out a strategy for EU in the area of photonics components and systems.

  13. Advanced technology component derating

    NASA Astrophysics Data System (ADS)

    Jennings, Timothy A.

    1992-02-01

    A technical study performed to determine the derating criteria of advanced technology components is summarized. The study covered existing criteria from AFSC Pamphlet 800-27 and the development of new criteria based on data, literature searches, and the use of advanced technology prediction methods developed in RADC-TR-90-72. The devices that were investigated were as follows: VHSIC, ASIC, MIMIC, Microprocessor, PROM, Power Transistors, RF Pulse Transistors, RF Multi-Transistor Packages, Photo Diodes, Photo Transistors, Opto-Electronic Couplers, Injection Laser Diodes, LED, Hybrid Deposited Film Resistors, Chip Resistors, and Capacitors and SAW devices. The results of the study are additional derating criteria that extend the range of AFSC Pamphlet 800-27. These data will be transitioned from the report to AFSC Pamphlet 800-27 for use by government and contractor personnel in derating electronics systems yielding increased safety margins and improved system reliability.

  14. funRNA: a fungi-centered genomics platform for genes encoding key components of RNAi.

    PubMed

    Choi, Jaeyoung; Kim, Ki-Tae; Jeon, Jongbum; Wu, Jiayao; Song, Hyeunjeong; Asiegbu, Fred O; Lee, Yong-Hwan

    2014-01-01

    RNA interference (RNAi) is involved in genome defense as well as diverse cellular, developmental, and physiological processes. Key components of RNAi are Argonaute, Dicer, and RNA-dependent RNA polymerase (RdRP), which have been functionally characterized mainly in model organisms. The key components are believed to exist throughout eukaryotes; however, there is no systematic platform for archiving and dissecting these important gene families. In addition, few fungi have been studied to date, limiting our understanding of RNAi in fungi. Here we present funRNA http://funrna.riceblast.snu.ac.kr/, a fungal kingdom-wide comparative genomics platform for putative genes encoding Argonaute, Dicer, and RdRP. To identify and archive genes encoding the abovementioned key components, protein domain profiles were determined from reference sequences obtained from UniProtKB/SwissProt. The domain profiles were searched using fungal, metazoan, and plant genomes, as well as bacterial and archaeal genomes. 1,163, 442, and 678 genes encoding Argonaute, Dicer, and RdRP, respectively, were predicted. Based on the identification results, active site variation of Argonaute, diversification of Dicer, and sequence analysis of RdRP were discussed in a fungus-oriented manner. funRNA provides results from diverse bioinformatics programs and job submission forms for BLAST, BLASTMatrix, and ClustalW. Furthermore, sequence collections created in funRNA are synced with several gene family analysis portals and databases, offering further analysis opportunities. funRNA provides identification results from a broad taxonomic range and diverse analysis functions, and could be used in diverse comparative and evolutionary studies. It could serve as a versatile genomics workbench for key components of RNAi.

  15. Key Findings and Recommendations for Technology Transfer at the ITS JPO

    DOT National Transportation Integrated Search

    2011-03-18

    This report provides key findings and recommendations for technology transfer at the Intelligent Transportation Systems Joint Program Office (ITS JPO) based upon an assessment of best practices in technology transfer in other industries, such as nati...

  16. Efficient Computational Prototyping of Mixed Technology Microfluidic Components and Systems

    DTIC Science & Technology

    2002-08-01

    AFRL-IF-RS-TR-2002-190 Final Technical Report August 2002 EFFICIENT COMPUTATIONAL PROTOTYPING OF MIXED TECHNOLOGY MICROFLUIDIC...SUBTITLE EFFICIENT COMPUTATIONAL PROTOTYPING OF MIXED TECHNOLOGY MICROFLUIDIC COMPONENTS AND SYSTEMS 6. AUTHOR(S) Narayan R. Aluru, Jacob White...Aided Design (CAD) tools for microfluidic components and systems were developed in this effort. Innovative numerical methods and algorithms for mixed

  17. Air Reserve Component: Key to the Air Force’s Future

    DTIC Science & Technology

    2013-03-01

    REPORT TYPE STRATEGY RESEARCH PROJECT .33 3. DATES COVERED (From - To) 4. TITLE AND SUBTITLE Air Reserve Component: Key to the Air Force’s...b. ABSTRACT UU c. THIS PAGE UU 19b. TELEPHONE NUMBER (Include area code) USAWC STRATEGY RESEARCH PROJECT...RAND Corporation, Prepared for the Office of Secretary of Defense, 2008), XV. 64 T.X. Hammes, "Offshore Control: A Proposed Strategy ," Infinity

  18. Intracellular self-assembly based multi-labeling of key viral components: Envelope, capsid and nucleic acids.

    PubMed

    Wen, Li; Lin, Yi; Zhang, Zhi-Ling; Lu, Wen; Lv, Cheng; Chen, Zhi-Liang; Wang, Han-Zhong; Pang, Dai-Wen

    2016-08-01

    Envelope, capsid and nucleic acids are key viral components that are all involved in crucial events during virus infection. Thus simultaneous labeling of these key components is an indispensable prerequisite for monitoring comprehensive virus infection process and dissecting virus infection mechanism. Baculovirus was genetically tagged with biotin on its envelope protein GP64 and enhanced green fluorescent protein (EGFP) on its capsid protein VP39. Spodoptera frugiperda 9 (Sf9) cells were infected by the recombinant baculovirus and subsequently fed with streptavidin-conjugated quantum dots (SA-QDs) and cell-permeable nucleic acids dye SYTO 82. Just by genetic engineering and virus propagation, multi-labeling of envelope, capsid and nucleic acids was spontaneously accomplished during virus inherent self-assembly process, significantly simplifying the labeling process while maintaining virus infectivity. Intracellular dissociation and transportation of all the key viral components, which was barely reported previously, was real-time monitored based on the multi-labeling approach, offering opportunities for deeply understanding virus infection and developing anti-virus treatment. Copyright © 2016 Elsevier Ltd. All rights reserved.

  19. Advanced component technologies for energy-efficient turbofan engines

    NASA Technical Reports Server (NTRS)

    Saunders, N. T.

    1980-01-01

    The paper reviews NASA's Energy Efficient Engine Project which was initiated to provide the advanced technology base for a new generation of fuel-conservative engines for introduction into airline service by the late 1980s. Efforts in this project are directed at advancing engine component and systems technologies to a point of demonstrating technology-readiness by 1984. Early results indicate high promise in achieving most of the goals established in the project.

  20. Miniaturization of components and systems for space using MEMS-technology

    NASA Astrophysics Data System (ADS)

    Grönland, Tor-Arne; Rangsten, Pelle; Nese, Martin; Lang, Martin

    2007-06-01

    Development of MEMS-based (micro electro mechanical system) components and subsystems for space applications has been pursued by various research groups and organizations around the world for at least two decades. The main driver for developing MEMS-based components for space is the miniaturization that can be achieved. Miniaturization can not only save orders of magnitude in mass and volume of individual components, but it can also allow increased redundancy, and enable novel spacecraft designs and mission scenarios. However, the commercial breakthrough of MEMS has not occurred within the space business as it has within other branches such as the IT/telecom or automotive industries, or as it has in biotech or life science applications. A main explanation to this is the highly conservative attitude to new technology within the space community. This conservatism is in many senses motivated by a very low risk acceptance in the few and costly space projects that actually ends with a space flight. To overcome this threshold there is a strong need for flight opportunities where reasonable risks can be accepted. Currently there are a few flight opportunities allowing extensive use of new technology in space, but one of the exceptions is the PRISMA program. PRISMA is an international (Sweden, Germany, France, Denmark, Norway, Greece) technology demonstration program with focus on rendezvous and formation flying. It is a two satellite LEO mission with a launch scheduled for the first half of 2009. On PRISMA, a number of novel technologies e.g. RF metrology sensor for Darwin, autonomous formation flying based on GPS and vision-based sensors, ADN-based "green propulsion" will be demonstrated in space for the first time. One of the satellites will also have a miniaturized propulsion system onboard based on MEMS-technology. This novel propulsion system includes two microthruster modules, each including four thrusters with micro- to milli-Newton thrust capability. The novelty

  1. Multi-cultural components and keys for European worldwide space programs

    NASA Astrophysics Data System (ADS)

    Pinotti, Roberto

    1991-12-01

    The role of different cultures in space missions is considered with regard to NASA and ESA astronauts and Russian cosmonauts. The identification of all the psychological and socio-anthropological components in the behavior of human groups in space is extremely important to understand and solve different problems and obtain the mission's success. In this light, the creation of a multicultural atmosphere aboard is considered a positive aspect for future space programs, and the synthesis of European cultural elements is a definite key to develop morale and productivity.

  2. Key technologies for manufacturing and processing sheet materials: A global perspective

    NASA Astrophysics Data System (ADS)

    Demeri, Mahmoud Y.

    2001-02-01

    Modern industrial technologies continue to seek new materials and processes to produce products that meet design and functional requirements. Sheet materials made from ferrous and non-ferrous metals, laminates, composites, and reinforced plastics constitute a large percentage of today’s products, components, and systems. Major manufacturers of sheet products include automotive, aerospace, appliance, and food-packaging industries. The Second Global Symposium on Innovations in Materials Processing & Manufacturing: Sheet Materials is organized to provide a forum for presenting advances in sheet processing and manufacturing by worldwide researchers and engineers from industrial, research, and academic centers. The symposium, sponsored by the TMS Materials Processing & Manufacturing Division (MPMD), was planned for the 2001 TMS Annual Meeting, New Orleans, Louisiana, February 11 15, 2001. This article is a review of key papers submitted for publication in the concurrent volume. The selected papers present significant developments in the rapidly expanding areas of advanced sheet materials, innovative forming methods, industrial applications, primary and secondary processing, composite processing, and numerical modeling of manufacturing processes.

  3. RFID: A key technology for Humanity

    NASA Astrophysics Data System (ADS)

    Duroc, Yvan; Tedjini, Smail

    2018-01-01

    The RFID (Radio Frequency IDentification) technology is a well-known wireless application for traceability, logistics, and access control. It became ubiquitous in industry and our daily life (ticketing, payment, passports, car keys, etc.). RFID is nowadays a standardized technology; its inherent advantages, which are unitary, identification, wireless communication, and low cost of tags, provide it with decisive practical benefits that drive new developments in terms of concepts and applications. This trend is largely confirmed by the market forecast, but also by its implementation in the area of health (smart hospital), assistance to persons, anti-counterfeiting, as well as by its perspective in terms of new paradigms for distributed ambient intelligence and the Internet of Things. The first part of this paper briefly reviews the fundamental concepts of the RFID technology, and shows its link with the radio science. A state of the art including the presentation of current performance and developments is also summarized. The second part illustrates the impact of RFID to the service of our society with a focus of applications in the field of autonomy and handicap. Finally, the last part highlights a panorama of perspectives and the future directions of RFID applications dedicated to the service of Humanity. xml:lang="fr"

  4. Sensitivity analysis of key components in large-scale hydroeconomic models

    NASA Astrophysics Data System (ADS)

    Medellin-Azuara, J.; Connell, C. R.; Lund, J. R.; Howitt, R. E.

    2008-12-01

    This paper explores the likely impact of different estimation methods in key components of hydro-economic models such as hydrology and economic costs or benefits, using the CALVIN hydro-economic optimization for water supply in California. In perform our analysis using two climate scenarios: historical and warm-dry. The components compared were perturbed hydrology using six versus eighteen basins, highly-elastic urban water demands, and different valuation of agricultural water scarcity. Results indicate that large scale hydroeconomic hydro-economic models are often rather robust to a variety of estimation methods of ancillary models and components. Increasing the level of detail in the hydrologic representation of this system might not greatly affect overall estimates of climate and its effects and adaptations for California's water supply. More price responsive urban water demands will have a limited role in allocating water optimally among competing uses. Different estimation methods for the economic value of water and scarcity in agriculture may influence economically optimal water allocation; however land conversion patterns may have a stronger influence in this allocation. Overall optimization results of large-scale hydro-economic models remain useful for a wide range of assumptions in eliciting promising water management alternatives.

  5. Active magnetic radiation shielding system analysis and key technologies.

    PubMed

    Washburn, S A; Blattnig, S R; Singleterry, R C; Westover, S C

    2015-01-01

    Many active magnetic shielding designs have been proposed in order to reduce the radiation exposure received by astronauts on long duration, deep space missions. While these designs are promising, they pose significant engineering challenges. This work presents a survey of the major systems required for such unconfined magnetic field design, allowing the identification of key technologies for future development. Basic mass calculations are developed for each system and are used to determine the resulting galactic cosmic radiation exposure for a generic solenoid design, using a range of magnetic field strength and thickness values, allowing some of the basic characteristics of such a design to be observed. This study focuses on a solenoid shaped, active magnetic shield design; however, many of the principles discussed are applicable regardless of the exact design configuration, particularly the key technologies cited. Copyright © 2015 The Committee on Space Research (COSPAR). All rights reserved.

  6. The ECAR Study of Undergraduate Students and Information Technology, 2010. Key Findings

    ERIC Educational Resources Information Center

    Smith, Shannon D.; Caruso, Judith Borreson

    2010-01-01

    This document presents the key findings from "The ECAR Study of Undergraduate Students and Information Technology, 2010". Since 2004, the annual ECAR (EDUCAUSE Center for Applied Research) study of undergraduate students and information technology has sought to shed light on how information technology affects the college experience. We…

  7. Central Component Descriptors for Levels of Technological Pedagogical Content Knowledge

    ERIC Educational Resources Information Center

    Niess, Margaret L.

    2013-01-01

    Technological pedagogical content knowledge (TPACK) proposes a theoretical framework that incorporates four central components: an overarching conception of what it means to teach with technology, knowledge of students' thinking and understandings of specific topics with technologies, knowledge of curricular materials that incorporate…

  8. Innovation in mental health services: what are the key components of success?

    PubMed

    Brooks, Helen; Pilgrim, David; Rogers, Anne

    2011-10-26

    Service development innovation in health technology and practice is viewed as a pressing need within the field of mental health yet is relatively poorly understood. Macro-level theories have been criticised for their limited explanatory power and they may not be appropriate for understanding local and fine-grained uncertainties of services and barriers to the sustainability of change. This study aimed to identify contextual influences inhibiting or promoting the acceptance and integration of innovations in mental health services in both National Health Service (NHS) and community settings. A comparative study using qualitative and case study data collection methods, including semi-structured interviews with key stakeholders and follow-up telephone interviews over a one-year period. The analysis was informed by learning organisation theory. Drawn from 11 mental health innovation projects within community, voluntary and NHS settings, 65 participants were recruited including service users, commissioners, health and non-health professionals, managers, and caregivers. The methods deployed in this evaluation focused on process-outcome links within and between the 11 projects. Key barriers to innovation included resistance from corporate departments and middle management, complexity of the innovation, and the availability and access to resources on a prospective basis within the host organisation. The results informed the construction of a proposed model of innovation implementation within mental health services. The main components of which are context, process, and outcomes. The study produced a model of conducive and impeding factors drawn from the composite picture of 11 innovative mental health projects, and this is discussed in light of relevant literature. The model provides a rich agenda to consider for services wanting to innovate or adopt innovations from elsewhere. The evaluation suggested the importance of studying innovation with a focus on context, process

  9. Innovation in mental health services: what are the key components of success?

    PubMed Central

    2011-01-01

    Background Service development innovation in health technology and practice is viewed as a pressing need within the field of mental health yet is relatively poorly understood. Macro-level theories have been criticised for their limited explanatory power and they may not be appropriate for understanding local and fine-grained uncertainties of services and barriers to the sustainability of change. This study aimed to identify contextual influences inhibiting or promoting the acceptance and integration of innovations in mental health services in both National Health Service (NHS) and community settings. Methods A comparative study using qualitative and case study data collection methods, including semi-structured interviews with key stakeholders and follow-up telephone interviews over a one-year period. The analysis was informed by learning organisation theory. Drawn from 11 mental health innovation projects within community, voluntary and NHS settings, 65 participants were recruited including service users, commissioners, health and non-health professionals, managers, and caregivers. The methods deployed in this evaluation focused on process-outcome links within and between the 11 projects. Results Key barriers to innovation included resistance from corporate departments and middle management, complexity of the innovation, and the availability and access to resources on a prospective basis within the host organisation. The results informed the construction of a proposed model of innovation implementation within mental health services. The main components of which are context, process, and outcomes. Conclusions The study produced a model of conducive and impeding factors drawn from the composite picture of 11 innovative mental health projects, and this is discussed in light of relevant literature. The model provides a rich agenda to consider for services wanting to innovate or adopt innovations from elsewhere. The evaluation suggested the importance of studying

  10. New dynamic silicon photonic components enabled by MEMS technology

    NASA Astrophysics Data System (ADS)

    Errando-Herranz, Carlos; Edinger, Pierre; Colangelo, Marco; Björk, Joel; Ahmed, Samy; Stemme, Göran; Niklaus, Frank; Gylfason, Kristinn B.

    2018-02-01

    Silicon photonics is the study and application of integrated optical systems which use silicon as an optical medium, usually by confining light in optical waveguides etched into the surface of silicon-on-insulator (SOI) wafers. The term microelectromechanical systems (MEMS) refers to the technology of mechanics on the microscale actuated by electrostatic actuators. Due to the low power requirements of electrostatic actuation, MEMS components are very power efficient, making them well suited for dense integration and mobile operation. MEMS components are conventionally also implemented in silicon, and MEMS sensors such as accelerometers, gyros, and microphones are now standard in every smartphone. By combining these two successful technologies, new active photonic components with extremely low power consumption can be made. We discuss our recent experimental work on tunable filters, tunable fiber-to-chip couplers, and dynamic waveguide dispersion tuning, enabled by the marriage of silicon MEMS and silicon photonics.

  11. Survey of key technologies on millimeter-wave CMOS integrated circuits

    NASA Astrophysics Data System (ADS)

    Yu, Fei; Gao, Lei; Li, Lixiang; Cai, Shuo; Wang, Wei; Wang, Chunhua

    2018-05-01

    In order to provide guidance for the development of high performance millimeter-wave complementary metal oxide semiconductor (MMW-CMOS) integrated circuits (IC), this paper provides a survey of key technologies on MMW-CMOS IC. Technical background of MMW wireless communications is described. Then the recent development of the critical technologies of the MMW-CMOS IC are introduced in detail and compared. A summarization is given, and the development prospects on MMW-CMOS IC are also discussed.

  12. Modelling Creativity: Identifying Key Components through a Corpus-Based Approach

    PubMed Central

    2016-01-01

    Creativity is a complex, multi-faceted concept encompassing a variety of related aspects, abilities, properties and behaviours. If we wish to study creativity scientifically, then a tractable and well-articulated model of creativity is required. Such a model would be of great value to researchers investigating the nature of creativity and in particular, those concerned with the evaluation of creative practice. This paper describes a unique approach to developing a suitable model of how creative behaviour emerges that is based on the words people use to describe the concept. Using techniques from the field of statistical natural language processing, we identify a collection of fourteen key components of creativity through an analysis of a corpus of academic papers on the topic. Words are identified which appear significantly often in connection with discussions of the concept. Using a measure of lexical similarity to help cluster these words, a number of distinct themes emerge, which collectively contribute to a comprehensive and multi-perspective model of creativity. The components provide an ontology of creativity: a set of building blocks which can be used to model creative practice in a variety of domains. The components have been employed in two case studies to evaluate the creativity of computational systems and have proven useful in articulating achievements of this work and directions for further research. PMID:27706185

  13. Modelling Creativity: Identifying Key Components through a Corpus-Based Approach.

    PubMed

    Jordanous, Anna; Keller, Bill

    2016-01-01

    Creativity is a complex, multi-faceted concept encompassing a variety of related aspects, abilities, properties and behaviours. If we wish to study creativity scientifically, then a tractable and well-articulated model of creativity is required. Such a model would be of great value to researchers investigating the nature of creativity and in particular, those concerned with the evaluation of creative practice. This paper describes a unique approach to developing a suitable model of how creative behaviour emerges that is based on the words people use to describe the concept. Using techniques from the field of statistical natural language processing, we identify a collection of fourteen key components of creativity through an analysis of a corpus of academic papers on the topic. Words are identified which appear significantly often in connection with discussions of the concept. Using a measure of lexical similarity to help cluster these words, a number of distinct themes emerge, which collectively contribute to a comprehensive and multi-perspective model of creativity. The components provide an ontology of creativity: a set of building blocks which can be used to model creative practice in a variety of domains. The components have been employed in two case studies to evaluate the creativity of computational systems and have proven useful in articulating achievements of this work and directions for further research.

  14. Getting to Grips with Education and Training for Industry. A Development of the Concept of Key Technologies.

    ERIC Educational Resources Information Center

    Clyde, Albert

    "Key technologies" is an umbrella term for appropriate technologies applied to give maximum economic benefit in particular circumstances that may cross traditional disciplinary boundaries. Development of the concept is necessitated by the rate of change of technological development. Key technologies may be classified in three groups related to…

  15. Rivers and Floodplains as Key Components of Global Terrestrial Water Storage Variability

    NASA Astrophysics Data System (ADS)

    Getirana, Augusto; Kumar, Sujay; Girotto, Manuela; Rodell, Matthew

    2017-10-01

    This study quantifies the contribution of rivers and floodplains to terrestrial water storage (TWS) variability. We use state-of-the-art models to simulate land surface processes and river dynamics and to separate TWS into its main components. Based on a proposed impact index, we show that surface water storage (SWS) contributes 8% of TWS variability globally, but that contribution differs widely among climate zones. Changes in SWS are a principal component of TWS variability in the tropics, where major rivers flow over arid regions and at high latitudes. SWS accounts for 22-27% of TWS variability in both the Amazon and Nile Basins. Changes in SWS are negligible in the Western U.S., Northern Africa, Middle East, and central Asia. Based on comparisons with Gravity Recovery and Climate Experiment-based TWS, we conclude that accounting for SWS improves simulated TWS in most of South America, Africa, and Southern Asia, confirming that SWS is a key component of TWS variability.

  16. Implementing recovery: an analysis of the key technologies in Scotland

    PubMed Central

    2011-01-01

    Background Over the past ten years the promotion of recovery has become a stated aim of mental health policies within a number of English speaking countries, including Scotland. Implementation of a recovery approach involves a significant reorientation of mental health services and practices, which often poses significant challenges for reformers. This article examines how four key technologies of recovery have assisted in the move towards the creation of a recovery-oriented mental health system in Scotland. Methods Drawing on documentary analysis and a series of interviews we examine the construction and implementation of four key recovery 'technologies' as they have been put to use in Scotland: recovery narratives, the Scottish Recovery Indicator (SRI), Wellness Recovery Action Planning (WRAP) and peer support. Results Our findings illuminate how each of these technologies works to instantiate, exemplify and disseminate a 'recovery orientation' at different sites within the mental health system in order to bring about a 'recovery oriented' mental health system. They also enable us to identify some of the factors that facilitate or hinder the effectiveness of those technologies in bringing about a change in how mental health services are delivered in Scotland. These finding provide a basis for some general reflections on the utility of 'recovery technologies' to implement a shift towards recovery in mental health services in Scotland and elsewhere. Conclusions Our analysis of this process within the Scottish context will be valuable for policy makers and service coordinators wishing to implement recovery values within their own national mental health systems. PMID:21569633

  17. Optoelectronics components and technology for optical networking in China: recent progress and future trends

    NASA Astrophysics Data System (ADS)

    Jiang, Shan; Liu, Shuihua

    2004-04-01

    Current optical communication systems are more and more relying on the advanced opto-electronic components. A series of revolutionary optical and optoelectronics components technology accounts for the fast progress and field deployment of high-capacity telecommunication and data-transmission systems. Since 1990s, the optical communication industry in China entered a high-speed development period and its wide deployment had already established the solid base for China information infrastructure. In this presentation, the main progress of optoelectronics components and technology in China are reviewed, which includes semiconductor laser diode/photo receiver, fiber optical amplifier, DWDM multiplexer/de-multiplexer, dispersion compensation components and all optical network node components, such as optical switch, OADM, tunable optical filters and variable optical attenuators, etc. Integration discrete components into monolithic/hybrid platform component is an inevitable choice for the consideration of performance, mass production and cost reduction. The current status and the future trends of OEIC and PIC components technology in China will also be discuss mainly on the monolithic integration DFB LD + EA modulator, and planar light-wave circuit (PLC) technology, etc.

  18. Flight demonstrator concept for key technologies enabling future reusable launch vehicles

    NASA Astrophysics Data System (ADS)

    Ishimoto, Shinji; Fujii, Kenji; Mori, Takeshi

    2005-07-01

    A research center in JAXA has recently started research on reusable launch vehicles according to its plan placing emphasis on advanced launch technology. It is planned to demonstrate key technologies using a rocket-powered winged vehicle, and concept studies on the flight demonstrator have been conducted. This paper describes the present research plan and introduces the most compact vehicle concept among some versions under consideration.

  19. Advanced Gas Turbine (AGT) Technology Development Project, ceramic component developments

    NASA Technical Reports Server (NTRS)

    Teneyck, M. O.; Macbeth, J. W.; Sweeting, T. B.

    1987-01-01

    The ceramic component technology development activity conducted by Standard Oil Engineered Materials Company while performing as a principal subcontractor to the Garrett Auxiliary Power Division for the Advanced Gas Turbine (AGT) Technology Development Project (NASA Contract DEN3-167) is summarized. The report covers the period October 1979 through July 1987, and includes information concerning ceramic technology work categorized as common and unique. The former pertains to ceramic development applicable to two parallel AGT projects established by NASA contracts DEN3-168 (AGT100) and DEN3-167 (AGT101), whereas the unique work solely pertains to Garrett directed activity under the latter contract. The AGT101 Technology Development Project is sponsored by DOE and administered by NASA-Lewis. Standard Oil directed its efforts toward the development of ceramic materials in the silicon-carbide family. Various shape forming and fabrication methods, and nondestructive evaluation techniques were explored to produce the static structural components for the ceramic engine. This permitted engine testing to proceed without program slippage.

  20. Evolving Systems: Adaptive Key Component Control and Inheritance of Passivity and Dissipativity

    NASA Technical Reports Server (NTRS)

    Frost, S. A.; Balas, M. J.

    2010-01-01

    We propose a new framework called Evolving Systems to describe the self-assembly, or autonomous assembly, of actively controlled dynamical subsystems into an Evolved System with a higher purpose. Autonomous assembly of large, complex flexible structures in space is a target application for Evolving Systems. A critical requirement for autonomous assembling structures is that they remain stable during and after assembly. The fundamental topic of inheritance of stability, dissipativity, and passivity in Evolving Systems is the primary focus of this research. In this paper, we develop an adaptive key component controller to restore stability in Nonlinear Evolving Systems that would otherwise fail to inherit the stability traits of their components. We provide sufficient conditions for the use of this novel control method and demonstrate its use on an illustrative example.

  1. Prescribed burning consumes key forest structural components: implications for landscape heterogeneity.

    PubMed

    Holland, Greg J; Clarke, Michael F; Bennett, Andrew F

    2017-04-01

    Prescribed burning to achieve management objectives is a common practice in fire-prone regions worldwide. Structural components of habitat that are combustible and slow to develop are particularly susceptible to change associated with prescribed burning. We used an experimental, "whole-landscape" approach to investigate the effect of differing patterns of prescribed burning on key habitat components (logs, stumps, dead trees, litter cover, litter depth, and understorey vegetation). Twenty-two landscapes (each ~100 ha) were selected in a dry forest ecosystem in southeast Australia. Experimental burns were conducted in 16 landscapes (stratified by burn extent) while six served as untreated controls. We measured habitat components prior to and after burning. Landscape burn extent ranged from 22% to 89% across the 16 burn treatments. With the exception of dead standing trees (no change), all measures of habitat components declined as a consequence of burning. The degree of loss increased as the extent to which a landscape was burned also increased. Prescribed burning had complex effects on the spatial heterogeneity (beta diversity) of structural components within landscapes. Landscapes that were more heterogeneous pre-fire were homogenized by burning, while those that were more homogenous pre-fire tended to display greater differentiation post-burning. Thus, the notion that patch mosaic burning enhances heterogeneity at the landscape-scale depends on prior conditions. These findings have important management implications. Where prescribed burns must be undertaken, effects on important resources can be moderated via control of burn characteristics (e.g., burn extent). Longer-term impacts of prescribed burning will be strongly influenced by the return interval, given the slow rate at which some structural components accumulate (decades to centuries). Management of habitat structural components is important given the critical role they play in (1) provision of habitat

  2. Additive Manufacturing Technology for Biomedical Components: A review

    NASA Astrophysics Data System (ADS)

    Aimi Zaharin, Haizum; Rani, Ahmad Majdi Abdul; Lenggo Ginta, Turnad; Azam, Farooq I.

    2018-03-01

    Over the last decades, additive manufacturing has shown potential application in ranging fields. No longer a prototyping technology, it is now being utilised as a manufacturing technology for giant industries such as the automotive, aircraft and recently in the medical industry. It is a very successful method that provides health-care solution in biomedical sectors by producing patient-specific prosthetics, improve tissues engineering and facilitate pre-operating session. This paper thus presents a brief overview of the most commercially important additive manufacturing technologies, which is currently available for fabricating biomedical components such as Stereolithography (SLA), Selective Laser Sintering (SLS), Selective Laser Melting (SLM), Fused Deposition Modelling (FDM) and Electron Beam Melting (EBM). It introduces the basic principles of the main process, highlights some of the beneficial applications in medical industry and the current limitation of applied technology.

  3. Research on key technology of space laser communication network

    NASA Astrophysics Data System (ADS)

    Chang, Chengwu; Huang, Huiming; Liu, Hongyang; Gao, Shenghua; Cheng, Liyu

    2016-10-01

    Since the 21st century, Spatial laser communication has made a breakthrough development. Europe, the United States, Japan and other space powers have carried out the test of spatial laser communication technology on-orbit, and put forward a series of plans. In 2011, China made the first technology demonstration of satellite-ground laser communication carried by HY-2 satellite. Nowadays, in order to improve the transmission rate of spatial network, the topic of spatial laser communication network is becoming a research hotspot at home and abroad. This thesis, from the basic problem of spatial laser communication network to solve, analyzes the main difference between spatial network and ground network, which draws forth the key technology of spatial laser communication backbone network, and systematically introduces our research on aggregation, addressing, architecture of spatial network. From the perspective of technology development status and trends, the thesis proposes the development route of spatial laser communication network in stages. So as to provide reference about the development of spatial laser communication network in China.

  4. Sizing Power Components of an Electrically Driven Tail Cone Thruster and a Range Extender

    NASA Technical Reports Server (NTRS)

    Jansen, Ralph H.; Bowman, Cheryl; Jankovsky, Amy

    2016-01-01

    The aeronautics industry has been challenged on many fronts to increase efficiency, reduce emissions, and decrease dependency on carbon-based fuels. This paper provides an overview of the turboelectric and hybrid electric technologies being developed under NASA's Advanced Air Transportation Technology (AATT) Project and discusses how these technologies can impact vehicle design. The discussion includes an overview of key hybrid electric studies and technology investments, the approach to making informed investment decisions based on key performance parameters and mission studies, and the power system architectures for two candidate aircraft. Finally, the power components for a single-aisle turboelectric aircraft with an electrically driven tail cone thruster and for a hybrid-electric nine-passenger aircraft with a range extender are parametrically sized, and the sensitivity of these components to key parameters is presented.

  5. Study of application and key technology of the high-energy laser weapon in optoelectronic countermeasure

    NASA Astrophysics Data System (ADS)

    Qu, Zhou; Xing, Hao; Wang, Dawei; Wang, Qiugui

    2015-10-01

    High-energy Laser weapon is a new-style which is developing rapidly nowadays. It is a one kind of direction energy weapon which can destroy the targets or make them invalid. High-energy Laser weapon has many merits such as concentrated energy, fast transmission, long operating range, satisfied precision, fast shift fire, anti-electromagnetic interference, reusability, cost-effectiveness. High-energy Laser weapon has huge potential for modern warfare since its laser beam launch attack to the target by the speed of light. High-energy Laser weapon can be deployed by multiple methods such as skyborne, carrier borne, vehicle-mounted, foundation, space platform. Besides the connection with command and control system, High-energy Laser weapon is consist of high-energy laser and beam steering. Beam steering is comprised of Large diameter launch system and Precision targeting systems. Meanwhile, beam steering includes the distance measurement of target location, detection system of television and infrared sensor, adaptive optical system of Laser atmospheric distortion correction. The development of laser technology is very fast in recent years. A variety of laser sources have been regarded as the key component in many optoelectronic devices. For directed energy weapon, the progress of laser technology has greatly improved the tactical effectiveness, such as increasing the range and strike precision. At the same time, the modern solid-state laser has become the ideal optical source for optical countermeasure, because it has high photoelectric conversion efficiency and small volume or weight. However, the total performance is limited by the mutual cooperation between different subsystems. The optical countermeasure is a complex technique after many years development. The key factor to evaluate the laser weapon can be formulated as laser energy density to target. This article elaborated the laser device technology of optoelectronic countermeasure and Photoelectric tracking

  6. Bringing together integration technologies in GaAs, InP and Si to deliver low-cost high performance DWDM optoelectronic components and solutions

    NASA Astrophysics Data System (ADS)

    Carter, Andrew C.; Wale, Michael J.; Simmons, T.; Whitbread, Neil; Asghari, M.

    2003-06-01

    A key attribute emerging in the optoelectronic component supply industry is the ability to deliver 'solution level' products rather than discrete optical components to equipment manufacturers. This approach is primarily aimed at reducing cost for the equipment manufacturer both in engineering and assembly. Such 'solutions' must be designed to be cost effective - offering costs substantially below discrete components - and must be compatible with subcontract board manufacture without the traditional and expensive skills of fibre handling, splicing and management. Examples of 'solutions' in this context may be the core of a multifunctional OADM or a DWDM laser transmitter subsystem, with modulation, wavelength and power management all included in a simple to use module. Essential to the cost effective production of such solutions is a high degree of optical/optoelectronic integration. Co-packaging of discrete components and electronics into modules will not deliver the cost reduction demanded. At Bookham Technology we have brought together what we believe to be the three key integration technologies - InP for monolithic tunable sources, GaAs for high performance integrated modulation and ASOC for smart passives and hybrid platforms - which can deliver this cost reduction, together with performance enhancement, over a wide range of applications. In the paper we will demonstrate and compare our above integration approaches with the competing alternatives and seek to show how the power of integration is finally being harnessed in optoelectronics, delivering radical cost reduction as well as enabling system concepts virtually impossible to achieve with discrete components. In the paper we will demonstrate and compare our above integration approaches with the competing alternatives and seek to show how the power of integration is finally being harnessed in optoelectronics, delivering radical cost reduction as well as enabling system concepts virtually impossible to

  7. Economic and Physical Linkages of the Information and Communication Technology (ICT) Service Industry to Key Industries of the Economy: An Ad Hoc Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Anderson, David M.; Hoffman, Michael G.; Niemeyer, Jackie M.

    This report examines the information and communications technology (ICT) services industry in response to an inquiry by the Department of Energy’s (DOE’s) Office of Energy Policy and Systems Analysis. The report answers several key questions: •How has the reliance on ICT services evolved in recent years for key infrastructure services such as air travel, freight transport, electricity and natural gas distribution, financial services, and critical health care, and for the household sector? •What ICT industry trends explain continued strong linkage to and reliance upon ICT? •What is the ICT industry’s reliance on grid-supplied power, uninterruptible power supplies, emergency generators andmore » back-up energy storage technologies? •What are the observed direct effects of ICT disruptions induced by electrical system failures in recent history and how resilient are the components of the ICT industry?« less

  8. Academic Primer Series: Key Papers About Teaching with Technology.

    PubMed

    Boysen-Osborn, Megan; Cooney, Robert; Gottlieb, Michael; Chan, Teresa M; Brown, Aaron; King, Andrew; Tobias, Adam; Thoma, Brent

    2017-06-01

    Modern learners have immediate, unlimited access to a wide variety of online resources . To appeal to this current generation of learners, educators must embrace the use of technology. However, educators must balance newer, novel technologies with traditional methods to achieve the best learning outcomes. Therefore, we aimed to review several papers useful for faculty members wishing to incorporate technology into instructional design. We identified a broad list of papers relevant to teaching and learning with technology within the online discussions of the Academic Life in Emergency Medicine (ALiEM) Faculty Incubator. This list was augmented with suggestions by a guest expert (BT) and an open call on Twitter (tagged with the #meded and #FOAMed hashtags) yielding 24 papers. We then conducted a modified three-round Delphi process within the authorship group, including junior and senior faculty members, to identify the most impactful papers. We pared the list of 24 papers to five that were most highly rated. Two were research papers and three were commentaries or editorials. The authorship group reviewed and summarized these papers with specific consideration to their value to junior educators and faculty developers. This is a key reading list for junior faculty members and faculty developers interested in teaching with technology. The commentary contextualizes the importance of these papers for medical educators, to optimize use of technology in their teaching or incorporate into faculty development.

  9. Enabling Technologies for Ceramic Hot Section Components

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Venkat Vedula; Tania Bhatia

    Silicon-based ceramics are attractive materials for use in gas turbine engine hot sections due to their high temperature mechanical and physical properties as well as lower density than metals. The advantages of utilizing ceramic hot section components include weight reduction, and improved efficiency as well as enhanced power output and lower emissions as a result of reducing or eliminating cooling. Potential gas turbine ceramic components for industrial, commercial and/or military high temperature turbine applications include combustor liners, vanes, rotors, and shrouds. These components require materials that can withstand high temperatures and pressures for long duration under steam-rich environments. For Navymore » applications, ceramic hot section components have the potential to increase the operation range. The amount of weight reduced by utilizing a lighter gas turbine can be used to increase fuel storage capacity while a more efficient gas turbine consumes less fuel. Both improvements enable a longer operation range for Navy ships and aircraft. Ceramic hot section components will also be beneficial to the Navy's Growth Joint Strike Fighter (JSF) and VAATE (Versatile Affordable Advanced Turbine Engines) initiatives in terms of reduced weight, cooling air savings, and capability/cost index (CCI). For DOE applications, ceramic hot section components provide an avenue to achieve low emissions while improving efficiency. Combustors made of ceramic material can withstand higher wall temperatures and require less cooling air. Ability of the ceramics to withstand high temperatures enables novel combustor designs that have reduced NO{sub x}, smoke and CO levels. In the turbine section, ceramic vanes and blades do not require sophisticated cooling schemes currently used for metal components. The saved cooling air could be used to further improve efficiency and power output. The objectives of this contract were to develop technologies critical for ceramic hot

  10. Key Technologies of Phone Storage Forensics Based on ARM Architecture

    NASA Astrophysics Data System (ADS)

    Zhang, Jianghan; Che, Shengbing

    2018-03-01

    Smart phones are mainly running Android, IOS and Windows Phone three mobile platform operating systems. The android smart phone has the best market shares and its processor chips are almost ARM software architecture. The chips memory address mapping mechanism of ARM software architecture is different with x86 software architecture. To forensics to android mart phone, we need to understand three key technologies: memory data acquisition, the conversion mechanism from virtual address to the physical address, and find the system’s key data. This article presents a viable solution which does not rely on the operating system API for a complete solution to these three issues.

  11. Ad hoc Laser networks component technology for modular spacecraft

    NASA Astrophysics Data System (ADS)

    Huang, Xiujun; Shi, Dele; Ma, Zongfeng; Shen, Jingshi

    2016-03-01

    Distributed reconfigurable satellite is a new kind of spacecraft system, which is based on a flexible platform of modularization and standardization. Based on the module data flow analysis of the spacecraft, this paper proposes a network component of ad hoc Laser networks architecture. Low speed control network with high speed load network of Microwave-Laser communication mode, no mesh network mode, to improve the flexibility of the network. Ad hoc Laser networks component technology was developed, and carried out the related performance testing and experiment. The results showed that ad hoc Laser networks components can meet the demand of future networking between the module of spacecraft.

  12. Ad hoc laser networks component technology for modular spacecraft

    NASA Astrophysics Data System (ADS)

    Huang, Xiujun; Shi, Dele; Shen, Jingshi

    2017-10-01

    Distributed reconfigurable satellite is a new kind of spacecraft system, which is based on a flexible platform of modularization and standardization. Based on the module data flow analysis of the spacecraft, this paper proposes a network component of ad hoc Laser networks architecture. Low speed control network with high speed load network of Microwave-Laser communication mode, no mesh network mode, to improve the flexibility of the network. Ad hoc Laser networks component technology was developed, and carried out the related performance testing and experiment. The results showed that ad hoc Laser networks components can meet the demand of future networking between the module of spacecraft.

  13. Establishing key components of yoga interventions for musculoskeletal conditions: a Delphi survey

    PubMed Central

    2014-01-01

    Background Evidence suggests yoga is a safe and effective intervention for the management of physical and psychosocial symptoms associated with musculoskeletal conditions. However, heterogeneity in the components and reporting of clinical yoga trials impedes both the generalization of study results and the replication of study protocols. The aim of this Delphi survey was to address these issues of heterogeneity, by developing a list of recommendations of key components for the design and reporting of yoga interventions for musculoskeletal conditions. Methods Recognised experts involved in the design, conduct, and teaching of yoga for musculoskeletal conditions were identified from a systematic review, and invited to contribute to the Delphi survey. Forty-one of the 58 experts contacted, representing six countries, agreed to participate. A three-round Delphi was conducted via electronic surveys. Round 1 presented an open-ended question, allowing panellists to individually identify components they considered key to the design and reporting of yoga interventions for musculoskeletal conditions. Thematic analysis of Round 1 identified items for quantitative rating in Round 2; items not reaching consensus were forwarded to Round 3 for re-rating. Results Thirty-six panellists (36/41; 88%) completed the three rounds of the Delphi survey. Panellists provided 348 comments to the Round 1 question. These comments were reduced to 49 items, grouped under five themes, for rating in subsequent rounds. A priori group consensus of ≥80% was reached on 28 items related to five themes concerning defining the yoga intervention, types of yoga practices to include in an intervention, delivery of the yoga protocol, domains of outcome measures, and reporting of yoga interventions for musculoskeletal conditions. Additionally, a priori consensus of ≥50% was reached on five items relating to minimum values for intervention parameters. Conclusions Expert consensus has provided a non

  14. Component Technology for High-Performance Scientific Simulation Software

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Epperly, T; Kohn, S; Kumfert, G

    2000-11-09

    We are developing scientific software component technology to manage the complexity of modem, parallel simulation software and increase the interoperability and re-use of scientific software packages. In this paper, we describe a language interoperability tool named Babel that enables the creation and distribution of language-independent software libraries using interface definition language (IDL) techniques. We have created a scientific IDL that focuses on the unique interface description needs of scientific codes, such as complex numbers, dense multidimensional arrays, complicated data types, and parallelism. Preliminary results indicate that in addition to language interoperability, this approach provides useful tools for thinking about themore » design of modem object-oriented scientific software libraries. Finally, we also describe a web-based component repository called Alexandria that facilitates the distribution, documentation, and re-use of scientific components and libraries.« less

  15. A brief review on key technologies in the battery management system of electric vehicles

    NASA Astrophysics Data System (ADS)

    Liu, Kailong; Li, Kang; Peng, Qiao; Zhang, Cheng

    2018-04-01

    Batteries have been widely applied in many high-power applications, such as electric vehicles (EVs) and hybrid electric vehicles, where a suitable battery management system (BMS) is vital in ensuring safe and reliable operation of batteries. This paper aims to give a brief review on several key technologies of BMS, including battery modelling, state estimation and battery charging. First, popular battery types used in EVs are surveyed, followed by the introduction of key technologies used in BMS. Various battery models, including the electric model, thermal model and coupled electro-thermal model are reviewed. Then, battery state estimations for the state of charge, state of health and internal temperature are comprehensively surveyed. Finally, several key and traditional battery charging approaches with associated optimization methods are discussed.

  16. Nanobonding: A key technology for emerging applications in health and environmental sciences

    NASA Astrophysics Data System (ADS)

    Howlader, Matiar M. R.; Deen, M. Jamal; Suga, Tadatomo

    2015-03-01

    In this paper, surface-activation-based nanobonding technology and its applications are described. This bonding technology allows for the integration of electronic, photonic, fluidic and mechanical components into small form-factor systems for emerging sensing and imaging applications in health and environmental sciences. Here, we describe four different nanobonding techniques that have been used for the integration of various substrates — silicon, gallium arsenide, glass, and gold. We use these substrates to create electronic (silicon), photonic (silicon and gallium arsenide), microelectromechanical (glass and silicon), and fluidic (silicon and glass) components for biosensing and bioimaging systems being developed. Our nanobonding technologies provide void-free, strong, and nanometer scale bonding at room temperature or at low temperatures (<200 °C), and do not require chemicals, adhesives, or high external pressure. The interfaces of the nanobonded materials in ultra-high vacuum and in air correspond to covalent bonds, and hydrogen or hydroxyl bonds, respectively.

  17. Evidence for the Induction of Key Components of the NOTCH Signaling Pathway via Deltamethrin and Azamethiphos Treatment in the Sea Louse Caligus rogercresseyi

    PubMed Central

    Boltaña, Sebastian; Chávez-Mardones, Jaqueline; Valenzuela-Muñoz, Valentina; Gallardo-Escárate, Cristian

    2016-01-01

    The extensive use of organophosphates and pyrethroids in the aquaculture industry has negatively impacted parasite sensitivity to the delousing effects of these antiparasitics, especially among sea lice species. The NOTCH signaling pathway is a positive regulator of ABC transporter subfamily C expression and plays a key role in the generation and modulation of pesticide resistance. However, little is known about the molecular mechanisms behind pesticide resistance, partly due to the lack of genomic and molecular information on the processes involved in the resistance mechanism of sea lice. Next-generation sequencing technologies provide an opportunity for rapid and cost-effective generation of genome-scale data. The present study, through RNA-seq analysis, determined that the sea louse Caligus rogercresseyi (C. rogercresseyi) specifically responds to the delousing drugs azamethiphos and deltamethrin at the transcriptomic level by differentially activating mRNA of the NOTCH signaling pathway and of ABC genes. These results suggest that frequent antiparasitic application may increase the activity of inhibitory mRNA components, thereby promoting inhibitory NOTCH output and conditions for increased resistance to delousing drugs. Moreover, data analysis underscored that key functions of NOTCH/ABC components were regulated during distinct phases of the drug response, thus indicating resistance modifications in C. rogercresseyi resulting from the frequent use of organophosphates and pyrethroids. PMID:27187362

  18. Evidence for the Induction of Key Components of the NOTCH Signaling Pathway via Deltamethrin and Azamethiphos Treatment in the Sea Louse Caligus rogercresseyi.

    PubMed

    Boltaña, Sebastian; Chávez-Mardones, Jaqueline; Valenzuela-Muñoz, Valentina; Gallardo-Escárate, Cristian

    2016-05-12

    The extensive use of organophosphates and pyrethroids in the aquaculture industry has negatively impacted parasite sensitivity to the delousing effects of these antiparasitics, especially among sea lice species. The NOTCH signaling pathway is a positive regulator of ABC transporter subfamily C expression and plays a key role in the generation and modulation of pesticide resistance. However, little is known about the molecular mechanisms behind pesticide resistance, partly due to the lack of genomic and molecular information on the processes involved in the resistance mechanism of sea lice. Next-generation sequencing technologies provide an opportunity for rapid and cost-effective generation of genome-scale data. The present study, through RNA-seq analysis, determined that the sea louse Caligus rogercresseyi (C. rogercresseyi) specifically responds to the delousing drugs azamethiphos and deltamethrin at the transcriptomic level by differentially activating mRNA of the NOTCH signaling pathway and of ABC genes. These results suggest that frequent antiparasitic application may increase the activity of inhibitory mRNA components, thereby promoting inhibitory NOTCH output and conditions for increased resistance to delousing drugs. Moreover, data analysis underscored that key functions of NOTCH/ABC components were regulated during distinct phases of the drug response, thus indicating resistance modifications in C. rogercresseyi resulting from the frequent use of organophosphates and pyrethroids.

  19. Assessing for Technological Literacy

    ERIC Educational Resources Information Center

    Engstrom, Daniel E.

    2004-01-01

    Designing standards-based assessment is a key component of a quality technology education program. For students to become technologically literate, it is important that the teacher understands how to measure student understandings and abilities in the study of technology. This article is written to help teachers and teacher educators recognize the…

  20. Academic Primer Series: Key Papers About Teaching with Technology

    PubMed Central

    Boysen-Osborn, Megan; Cooney, Robert; Gottlieb, Michael; Chan, Teresa M.; Brown, Aaron; King, Andrew; Tobias, Adam; Thoma, Brent

    2017-01-01

    Introduction Modern learners have immediate, unlimited access to a wide variety of online resources. To appeal to this current generation of learners, educators must embrace the use of technology. However, educators must balance newer, novel technologies with traditional methods to achieve the best learning outcomes. Therefore, we aimed to review several papers useful for faculty members wishing to incorporate technology into instructional design. Methods We identified a broad list of papers relevant to teaching and learning with technology within the online discussions of the Academic Life in Emergency Medicine (ALiEM) Faculty Incubator. This list was augmented with suggestions by a guest expert (BT) and an open call on Twitter (tagged with the #meded and #FOAMed hashtags) yielding 24 papers. We then conducted a modified three-round Delphi process within the authorship group, including junior and senior faculty members, to identify the most impactful papers. Results We pared the list of 24 papers to five that were most highly rated. Two were research papers and three were commentaries or editorials. The authorship group reviewed and summarized these papers with specific consideration to their value to junior educators and faculty developers. Conclusion This is a key reading list for junior faculty members and faculty developers interested in teaching with technology. The commentary contextualizes the importance of these papers for medical educators, to optimize use of technology in their teaching or incorporate into faculty development. PMID:28611895

  1. Liquid Oxygen/Liquid Methane Component Technology Development at MSFC

    NASA Technical Reports Server (NTRS)

    Robinson, Joel W.

    2010-01-01

    The National Aeronautics & Space Administration (NASA) has identified Liquid Oxygen (LOX)/Liquid Methane (LCH4) as a potential propellant combination for future space vehicles based upon exploration studies. The technology is estimated to have higher performance and lower overall systems mass compared to existing hypergolic propulsion systems. Besides existing in-house risk reduction activities, NASA has solicited from industry their participation on component technologies based on the potential application to the lunar ascent main engine (AME). Contracted and NASA efforts have ranged from valve technologies to engine system testbeds. The application for the AME is anticipated to be an expendable, pressure-fed engine for ascent from the moon at completion of its lunar stay. Additionally, the hardware is expected to provide an abort capability prior to landing, in the event that descent systems malfunction. For the past 4 years, MSFC has been working with the Glenn Research Center and the Johnson Space Center on methane technology development. This paper will focus on efforts specific to MSFC in pursuing ignition, injector performance, chamber material assessments and cryogenic valve technologies. Ignition studies have examined characteristics for torch, spark and microwave systems. Injector testing has yielded insight into combustion performance for shear, swirl and impinging type injectors. The majority of chamber testing has been conducted with ablative and radiatively cooled chambers with planned activities for regenerative and transpiration cooled chambers. Lastly, an effort is underway to examine the long duration exposure issues of cryogenic valve internal components. The paper will summarize the status of these efforts.

  2. Reduction of PM emissions from specific sources reflected on key components concentrations of ambient PM10

    NASA Astrophysics Data System (ADS)

    Minguillon, M. C.; Querol, X.; Monfort, E.; Alastuey, A.; Escrig, A.; Celades, I.; Miro, J. V.

    2009-04-01

    The relationship between specific particulate emission control and ambient levels of some PM10 components (Zn, As, Pb, Cs, Tl) was evaluated. To this end, the industrial area of Castellón (Eastern Spain) was selected, where around 40% of the EU glazed ceramic tiles and a high proportion of EU ceramic frits (middle product for the manufacture of ceramic glaze) are produced. The PM10 emissions from the ceramic processes were calculated over the period 2000 to 2007 taking into account the degree of implementation of corrective measures throughout the study period. Abatement systems (mainly bag filters) were implemented in the majority of the fusion kilns for frit manufacture in the area as a result of the application of the Directive 1996/61/CE, leading to a marked decrease in PM10 emissions. On the other hand, ambient PM10 sampling was carried out from April 2002 to July 2008 at three urban sites and one suburban site of the area and a complete chemical analysis was made for about 35 % of the collected samples, by means of different techniques (ICP-AES, ICP-MS, Ion Chromatography, selective electrode and elemental analyser). The series of chemical composition of PM10 allowed us to apply a source contribution model (Principal Component Analysis), followed by a multilinear regression analysis, so that PM10 sources were identified and their contribution to bulk ambient PM10 was quantified on a daily basis, as well as the contribution to bulk ambient concentrations of the identified key components (Zn, As, Pb, Cs, Tl). The contribution of the sources identified as the manufacture and use of ceramic glaze components, including the manufacture of ceramic frits, accounted for more than 65, 75, 58, 53, and 53% of ambient Zn, As, Pb, Cs and Tl levels, respectively (with the exception of Tl contribution at one of the sites). The important emission reductions of these sources during the study period had an impact on ambient key components levels, such that there was a high

  3. Alternative Solvents and Technologies for Precision Cleaning of Aerospace Components

    NASA Technical Reports Server (NTRS)

    Grandelli, Heather; Maloney, Phillip; DeVor, Robert; Hintze, Paul

    2014-01-01

    Precision cleaning solvents for aerospace components and oxygen fuel systems, including currently used Vertrel-MCA, have a negative environmental legacy, high global warming potential, and have polluted cleaning sites. Thus, alternative solvents and technologies are being investigated with the aim of achieving precision contamination levels of less than 1 mg/sq ft. The technologies being evaluated are ultrasonic bath cleaning, plasma cleaning and supercritical carbon dioxide cleaning.

  4. Aerospace laser communications technology as enabler for worldwide quantum key distribution

    NASA Astrophysics Data System (ADS)

    Moll, Florian; Weinfurter, Harald; Rau, Markus; Schmidt, Christopher; Melén, Gwen; Vogl, Tobias; Nauerth, Sebastian; Fuchs, Christian

    2016-04-01

    A worldwide growing interest in fast and secure data communications pushes technology development along two lines. While fast communications can be realized using laser communications in fiber and free-space, inherently secure communications can be achieved using quantum key distribution (QKD). By combining both technologies in a single device, many synergies can be exploited, therefore reducing size, weight and power of future systems. In recent experiments we demonstrated quantum communications over large distances as well as between an aircraft and a ground station which proved the feasibility of QKD between moving partners. Satellites thus may be used as trusted nodes in combination with QKD receiver stations on ground, thereby enabling fast and secure communications on a global scale. We discuss the previous experiment with emphasis on necessary developments to be done and corresponding ongoing research work of German Aerospace Center (DLR) and Ludwig Maximilians University Munich (LMU). DLR is performing research on satellite and ground terminals for the high-rate laser communication component, which are enabling technologies for the QKD link. We describe the concept and hardware of three generations of OSIRIS (Optical High Speed Infrared Link System) laser communication terminals for low Earth orbiting satellites. The first type applies laser beam pointing solely based on classical satellite control, the second uses an optical feedback to the satellite bus and the third, currently being in design phase, comprises of a special coarse pointing assembly to control beam direction independent of satellite orientation. Ongoing work also targets optical terminals for CubeSats. A further increase of beam pointing accuracy can be achieved with a fine pointing assembly. Two ground stations will be available for future testing, an advanced stationary ground station and a transportable ground station. In parallel the LMU QKD source size will be reduced by more than an

  5. NDE: A key to engine rotor life prediction

    NASA Technical Reports Server (NTRS)

    Doherty, J. E.

    1977-01-01

    A key ingredient in the establishment of safe life times for critical components is the means of reliably detecting flaws which may potentially exist. Currently used nondestructive evaluation procedures are successful in detecting life limiting defects; however, the development of automated and computer aided NDE technology permits even greater assurance of flight safety.

  6. Medical technology as a key driver of rising health expenditure: disentangling the relationship

    PubMed Central

    Sorenson, Corinna; Drummond, Michael; Bhuiyan Khan, Beena

    2013-01-01

    Health care spending has risen steadily in most countries, becoming a concern for decision-makers worldwide. Commentators often point to new medical technology as the key driver for burgeoning expenditures. This paper critically appraises this conjecture, based on an analysis of the existing literature, with the aim of offering a more detailed and considered analysis of this relationship. Several databases were searched to identify relevant literature. Various categories of studies (eg, multivariate and cost-effectiveness analyses) were included to cover different perspectives, methodological approaches, and issues regarding the link between medical technology and costs. Selected articles were reviewed and relevant information was extracted into a standardized template and analyzed for key cross-cutting themes, ie, impact of technology on costs, factors influencing this relationship, and methodological challenges in measuring such linkages. A total of 86 studies were reviewed. The analysis suggests that the relationship between medical technology and spending is complex and often conflicting. Findings were frequently contingent on varying factors, such as the availability of other interventions, patient population, and the methodological approach employed. Moreover, the impact of technology on costs differed across technologies, in that some (eg, cancer drugs, invasive medical devices) had significant financial implications, while others were cost-neutral or cost-saving. In light of these issues, we argue that decision-makers and other commentators should extend their focus beyond costs solely to include consideration of whether medical technology results in better value in health care and broader socioeconomic benefits. PMID:23807855

  7. Optical components damage parameters database system

    NASA Astrophysics Data System (ADS)

    Tao, Yizheng; Li, Xinglan; Jin, Yuquan; Xie, Dongmei; Tang, Dingyong

    2012-10-01

    Optical component is the key to large-scale laser device developed by one of its load capacity is directly related to the device output capacity indicators, load capacity depends on many factors. Through the optical components will damage parameters database load capacity factors of various digital, information technology, for the load capacity of optical components to provide a scientific basis for data support; use of business processes and model-driven approach, the establishment of component damage parameter information model and database systems, system application results that meet the injury test optical components business processes and data management requirements of damage parameters, component parameters of flexible, configurable system is simple, easy to use, improve the efficiency of the optical component damage test.

  8. ECITE: A Testbed for Assessment of Technology Interoperability and Integration wiht Architecture Components

    NASA Astrophysics Data System (ADS)

    Graves, S. J.; Keiser, K.; Law, E.; Yang, C. P.; Djorgovski, S. G.

    2016-12-01

    ECITE (EarthCube Integration and Testing Environment) is providing both cloud-based computational testing resources and an Assessment Framework for Technology Interoperability and Integration. NSF's EarthCube program is funding the development of cyberinfrastructure building block components as technologies to address Earth science research problems. These EarthCube building blocks need to support integration and interoperability objectives to work towards a coherent cyberinfrastructure architecture for the program. ECITE is being developed to provide capabilities to test and assess the interoperability and integration across funded EarthCube technology projects. EarthCube defined criteria for interoperability and integration are applied to use cases coordinating science problems with technology solutions. The Assessment Framework facilitates planning, execution and documentation of the technology assessments for review by the EarthCube community. This presentation will describe the components of ECITE and examine the methodology of cross walking between science and technology use cases.

  9. Application and the key technology on high power fiber-optic laser in laser weapon

    NASA Astrophysics Data System (ADS)

    Qu, Zhou; Li, Qiushi; Meng, Haihong; Sui, Xin; Zhang, Hongtao; Zhai, Xuhua

    2014-12-01

    The soft-killing laser weapon plays an important role in photoelectric defense technology. It can be used for photoelectric detection, search, blinding of photoelectric sensor and other devices on fire control and guidance devices, therefore it draws more and more attentions by many scholars. High power fiber-optic laser has many virtues such as small volume, simple structure, nimble handling, high efficiency, qualified light beam, easy thermal management, leading to blinding. Consequently, it may be used as the key device of soft-killing laser weapon. The present study introduced the development of high power fiber-optic laser and its main features. Meanwhile the key technology of large mode area (LMA) optical fiber design, the beam combination technology, double-clad fiber technology and pumping optical coupling technology was stated. The present study is aimed to design high doping LMA fiber, ensure single mode output by increasing core diameter and decrease NA. By means of reducing the spontaneous emission particle absorbed by fiber core and Increasing the power density in the optical fiber, the threshold power of nonlinear effect can increase, and the power of single fiber will be improved. Meantime, high power will be obtained by the beam combination technology. Application prospect of high power fiber laser in photoelectric defense technology was also set forth. Lastly, the present study explored the advantages of high power fiber laser in photoelectric defense technology.

  10. Recommendations for strengthening the infrared technology component of any condition monitoring program

    NASA Astrophysics Data System (ADS)

    Nicholas, Jack R., Jr.; Young, R. K.

    1999-03-01

    place the condition monitoring program in perspective); (11) Use of procedures for Predictive, Condition Monitoring and maintenance in general (To get consistent results); (12) Developing a scheme for predictive, condition monitoring personnel qualification and certification (To provide a career path and incentive to advance skill level and value to the company); (13) Analyst Assignment to Technologies and Related Duties (To make intelligent use of the skills of individuals assigned); (14) Condition Monitoring Analyst Selection Criteria (Key attributes for success are mentioned.); (15) Design and Modification to Support Monitoring (For old and new machinery to facilitate data acquisition); (16) Establishment of a Museum of Components and Samples Pulled from Service for Cause (For orientation and awareness training of operators and managers and exchange of information between analysts); (17) Goals (To promote a proactive program approach for machinery condition improvement).

  11. SUPERFUND INNOVATIVE TECHNOLOGY EVALUATION PROGRAM: TECHNOLOGY WITH AN IMPACT

    EPA Science Inventory

    SITE promotes the development and implementation of innovative technologies for remediating hazardous waste sites and for evaluating the nature and extent of hazardous waste site contamination through four component segments. The SITE Program is a key element in EPA's efforts...

  12. Research on key technologies of LADAR echo signal simulator

    NASA Astrophysics Data System (ADS)

    Xu, Rui; Shi, Rui; Ye, Jiansen; Wang, Xin; Li, Zhuo

    2015-10-01

    LADAR echo signal simulator is one of the most significant components of hardware-in-the-loop (HWIL) simulation systems for LADAR, which is designed to simulate the LADAR return signal in laboratory conditions. The device can provide the laser echo signal of target and background for imaging LADAR systems to test whether it is of good performance. Some key technologies are investigated in this paper. Firstly, the 3D model of typical target is built, and transformed to the data of the target echo signal based on ranging equation and targets reflection characteristics. Then, system model and time series model of LADAR echo signal simulator are established. Some influential factors which could induce fixed delay error and random delay error on the simulated return signals are analyzed. In the simulation system, the signal propagating delay of circuits and the response time of pulsed lasers are belong to fixed delay error. The counting error of digital delay generator, the jitter of system clock and the desynchronized between trigger signal and clock signal are a part of random delay error. Furthermore, these system insertion delays are analyzed quantitatively, and the noisy data are obtained. The target echo signals are got by superimposing of the noisy data and the pure target echo signal. In order to overcome these disadvantageous factors, a method of adjusting the timing diagram of the simulation system is proposed. Finally, the simulated echo signals are processed by using a detection algorithm to complete the 3D model reconstruction of object. The simulation results reveal that the range resolution can be better than 8 cm.

  13. The Key Technologies. Some Implications for Education and Training. An Occasional Paper.

    ERIC Educational Resources Information Center

    Mansell, Jack; And Others

    National competitiveness depends in large part on the practical application of technologies. Educational planners must, therefore, identify key (newly emerging) topics in science and engineering that are likely to have a major evolutionary effect on industry and incorporate these areas into existing vocational and technical curricula. Because…

  14. Digital security technology simplified.

    PubMed

    Scaglione, Bernard J

    2007-01-01

    Digital security technology is making great strides in replacing analog and other traditional security systems including CCTV card access, personal identification and alarm monitoring applications. Like any new technology, the author says, it is important to understand its benefits and limitations before purchasing and installing, to ensure its proper operation and effectiveness. This article is a primer for security directors on how digital technology works. It provides an understanding of the key components which make up the foundation for digital security systems, focusing on three key aspects of the digital security world: the security network, IP cameras and IP recorders.

  15. Thermoelectric Energy Conversion: Future Directions and Technology Development Needs

    NASA Technical Reports Server (NTRS)

    Fleurial, Jean-Pierre

    2007-01-01

    This viewgraph presentation reviews the process of thermoelectric energy conversion along with key technology needs and challenges. The topics include: 1) The Case for Thermoelectrics; 2) Advances in Thermoelectrics: Investment Needed; 3) Current U.S. Investment (FY07); 4) Increasing Thermoelectric Materials Conversion Efficiency Key Science Needs and Challenges; 5) Developing Advanced TE Components & Systems Key Technology Needs and Challenges; 6) Thermoelectrics; 7) 200W Class Lightweight Portable Thermoelectric Generator; 8) Hybrid Absorption Cooling/TE Power Cogeneration System; 9) Major Opportunities in Energy Industry; 10) Automobile Waste Heat Recovery; 11) Thermoelectrics at JPL; 12) Recent Advances at JPL in Thermoelectric Converter Component Technologies; 13) Thermoelectrics Background on Power Generation and Cooling Operational Modes; 14) Thermoelectric Power Generation; and 15) Thermoelectric Cooling.

  16. Enhancement of inorganic Martian dust simulant with carbon component and its effects on key characteristics of glutamatergic neurotransmission

    NASA Astrophysics Data System (ADS)

    Borisova, Tatiana; Krisanova, Natalia; Nazarova, Anastasiya; Borysov, Arseniy; Pastukhov, Artem; Pozdnyakova, Natalia; Dudarenko, Marina

    2016-07-01

    Evidence on the past existence of subsurface organic-bearing fluids on Mars was recently achieved basing on the investigation of organic carbon from the Tissint Martian meteorite (Lin et al., 2014). Tremendous amount of meteorites containing abundant carbon and carbon-enriched dust particles have reached the Earth daily (Pizzarello and Shock 2010). National Institute of Environmental Health Sciences/National Institute of Health panel of research scientists revealed recently that accumulating evidences suggest that nano-sized air pollution may have a significant impact on central nervous system in health and disease (Block et al., Neurotoxicology, 2012). During inhalation, nano-/microsized particles are efficiently deposited in nasal, tracheobronchial, and alveolar regions and can be transported to the central nervous system (Oberdorster et al., 2004). Based on above facts, the aims of this study were: 1) to upgrade inorganic Martian dust stimulant derived from volcanic ash (JSC-1a/JSC, ORBITEC Orbital Technologies Corporation, Madison, Wisconsin) by the addition of carbon components, that is, nanodiamonds; 2) to analyse acute effects of upgraded stimulant on the key characteristic of synaptic neurotransmission and to compare its effects with those of inorganic dust and carbon components per se. Acute administration of carbon-containing Martian dust analogue resulted in a significant decrease in Na+-dependent uptake of L-[14C]glutamate that is the major excitatory neurotransmitter in the central nervous system (CNS). The ambient level of the neurotransmitter in the preparation of isolated rat brain nerve terminals increased in the presence of carbon-contained Martian dust analogue. This fact indicated that carbon component of native Martian dust can have deleterious effects on extracellular glutamate homeostasis in the CNS, and so glutamatergic neurtransmission.

  17. Study of multipactor suppression of microwave components using perforated waveguide technology for space applications

    NASA Astrophysics Data System (ADS)

    Ye, Ming; Li, Yun; He, Yongning; Daneshmand, Mojgan

    2017-05-01

    With the development of space technology, microwave components with increased power handling capability and reduced weight have been urgently required. In this work, the perforated waveguide technology is proposed to suppress the multipactor effect of high power microwave components. Meanwhile, this novel method has the advantage of reducing components' weight, which makes it to have great potential in space applications. The perforated part of the waveguide components can be seen as an electron absorber (namely, its total electron emission yield is zero) since most of the electrons impacting on this part will go out of the components. Based on thoroughly benchmarked numerical simulation procedures, we simulated an S band and an X band waveguide transformer to conceptually verify this idea. Both electron dynamic simulations and electrical loss simulations demonstrate that the perforation technology can improve the multipactor threshold at least ˜8 dB while maintaining the acceptable insertion loss level compared with its un-perforated components. We also found that the component with larger minimum gap is easier to achieve multipactor suppression. This effect is interpreted by a parallel plate waveguide model. What's more, to improve the multipactor threshold of the X band waveguide transformer with a minimum gap of ˜0.1 mm, we proposed a perforation structure with the slope edge and explained its mechanism. Future study will focus on further optimization of the perforation structure, size, and distribution to maximize the comprehensive performances of microwave components.

  18. Pricing in health care organizations. A key component of the marketing mix.

    PubMed

    Marlowe, D

    1989-01-01

    Pricing is one of the key components of a successful marketing mix. Pricing objectives, strategies, and tactics cannot stand alone, however. To be effective, price must work in harmony with other marketing and management activities. Despite its importance, use of pricing as a management tool is limited in health care compared to other industries. Many factors contribute to this situation, including the structure of the health-care exchange process, limited consumer knowledge, and a limited ability to measure costs. I will provide an overview of pricing information, both within and outside health care. Specifically, we will explore the definition of pricing, nonmonetary pricing, price elasticity, classical pricing theory, and the role of pricing in a health-care setting.

  19. Pricing and components analysis of some key essential pediatric medicine in Odisha state

    PubMed Central

    Samal, Satyajit; Swain, Trupti Rekha

    2017-01-01

    Objective: Study highlighting prices, i.e., the patients actually pay at ground level is important for interventions such as alternate procurement schemes or to expedite regulatory assessment of essential medicines for children. The present study was undertaken to study pricing and component analysis of few key essential medicines in Odisha state. Methodology: Six child-specific medicines of different formulations were selected based on use in different disease condition and having widest pricing variation. Data were collected, entered, and analyzed in the price components data collection form of the World Health Organization-Health Action International (WHO-HAI) 2007 Workbook version 5 – Part II provided as part of the WHO/HAI methodology. The analysis includes the cumulative percent markup, total cumulative percent markup, and percent contribution of individual components to the final medicine price in both public and private sector of Odisha state. Results: Add-on costs such as taxes, wholesale, and retail markups contribute substantially to the final price of medicines in private sector, particularly for branded-generic products. The largest contributor to add-on costs is at the level of retailer shop. Conclusion: Policy should be framed to achieve a greater transparency and uniformity of the pricing of medicines at different health sectors of Odisha. PMID:28458429

  20. Pricing and components analysis of some key essential pediatric medicine in Odisha state.

    PubMed

    Samal, Satyajit; Swain, Trupti Rekha

    2017-01-01

    Study highlighting prices, i.e., the patients actually pay at ground level is important for interventions such as alternate procurement schemes or to expedite regulatory assessment of essential medicines for children. The present study was undertaken to study pricing and component analysis of few key essential medicines in Odisha state. Six child-specific medicines of different formulations were selected based on use in different disease condition and having widest pricing variation. Data were collected, entered, and analyzed in the price components data collection form of the World Health Organization-Health Action International (WHO-HAI) 2007 Workbook version 5 - Part II provided as part of the WHO/HAI methodology. The analysis includes the cumulative percent markup, total cumulative percent markup, and percent contribution of individual components to the final medicine price in both public and private sector of Odisha state. Add-on costs such as taxes, wholesale, and retail markups contribute substantially to the final price of medicines in private sector, particularly for branded-generic products. The largest contributor to add-on costs is at the level of retailer shop. Policy should be framed to achieve a greater transparency and uniformity of the pricing of medicines at different health sectors of Odisha.

  1. Internet MEMS design tools based on component technology

    NASA Astrophysics Data System (ADS)

    Brueck, Rainer; Schumer, Christian

    1999-03-01

    The micro electromechanical systems (MEMS) industry in Europe is characterized by small and medium sized enterprises specialized on products to solve problems in specific domains like medicine, automotive sensor technology, etc. In this field of business the technology driven design approach known from micro electronics is not appropriate. Instead each design problem aims at its own, specific technology to be used for the solution. The variety of technologies at hand, like Si-surface, Si-bulk, LIGA, laser, precision engineering requires a huge set of different design tools to be available. No single SME can afford to hold licenses for all these tools. This calls for a new and flexible way of designing, implementing and distributing design software. The Internet provides a flexible manner of offering software access along with methodologies of flexible licensing e.g. on a pay-per-use basis. New communication technologies like ADSL, TV cable of satellites as carriers promise to offer a bandwidth sufficient even for interactive tools with graphical interfaces in the near future. INTERLIDO is an experimental tool suite for process specification and layout verification for lithography based MEMS technologies to be accessed via the Internet. The first version provides a Java implementation even including a graphical editor for process specification. Currently, a new version is brought into operation that is based on JavaBeans component technology. JavaBeans offers the possibility to realize independent interactive design assistants, like a design rule checking assistants, a process consistency checking assistants, a technology definition assistants, a graphical editor assistants, etc. that may reside distributed over the Internet, communicating via Internet protocols. Each potential user thus is able to configure his own dedicated version of a design tool set dedicated to the requirements of the current problem to be solved.

  2. Public key infrastructure for DOE security research

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Aiken, R.; Foster, I.; Johnston, W.E.

    This document summarizes the Department of Energy`s Second Joint Energy Research/Defence Programs Security Research Workshop. The workshop, built on the results of the first Joint Workshop which reviewed security requirements represented in a range of mission-critical ER and DP applications, discussed commonalties and differences in ER/DP requirements and approaches, and identified an integrated common set of security research priorities. One significant conclusion of the first workshop was that progress in a broad spectrum of DOE-relevant security problems and applications could best be addressed through public-key cryptography based systems, and therefore depended upon the existence of a robust, broadly deployed public-keymore » infrastructure. Hence, public-key infrastructure ({open_quotes}PKI{close_quotes}) was adopted as a primary focus for the second workshop. The Second Joint Workshop covered a range of DOE security research and deployment efforts, as well as summaries of the state of the art in various areas relating to public-key technologies. Key findings were that a broad range of DOE applications can benefit from security architectures and technologies built on a robust, flexible, widely deployed public-key infrastructure; that there exists a collection of specific requirements for missing or undeveloped PKI functionality, together with a preliminary assessment of how these requirements can be met; that, while commercial developments can be expected to provide many relevant security technologies, there are important capabilities that commercial developments will not address, due to the unique scale, performance, diversity, distributed nature, and sensitivity of DOE applications; that DOE should encourage and support research activities intended to increase understanding of security technology requirements, and to develop critical components not forthcoming from other sources in a timely manner.« less

  3. Experimental Design for Evaluating Selected Nondestructive Measurement Technologies - Advanced Reactor Technology Milestone: M3AT-16PN2301043

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ramuhalli, Pradeep; Hirt, Evelyn H.; Pitman, Stan G.

    The harsh environments in advanced reactors (AdvRx) increase the possibility of degradation of safety-critical passive components, and therefore pose a particular challenge for deployment and extended operation of these concepts. Nondestructive evaluation technologies are an essential element for obtaining information on passive component condition in AdvRx, with the development of sensor technologies for nondestructively inspecting AdvRx passive components identified as a key need. Given the challenges posed by AdvRx environments and the potential needs for reducing the burden posed by periodic in-service inspection of hard-to-access and hard-to-replace components, a viable solution may be provided by online condition monitoring of components.more » This report identifies the key challenges that will need to be overcome for sensor development in this context, and documents an experimental plan for sensor development, test, and evaluation. The focus of initial research and development is on sodium fast reactors, with the eventual goal of the research being developing the necessary sensor technology, quantifying sensor survivability and long-term measurement reliability for nondestructively inspecting critical components. Materials for sensor development that are likely to withstand the harsh environments are described, along with a status on the fabrication of reference specimens, and the planned approach for design and evaluation of the sensor and measurement technology.« less

  4. Living technology: exploiting life's principles in technology.

    PubMed

    Bedau, Mark A; McCaskill, John S; Packard, Norman H; Rasmussen, Steen

    2010-01-01

    The concept of living technology-that is, technology that is based on the powerful core features of life-is explained and illustrated with examples from artificial life software, reconfigurable and evolvable hardware, autonomously self-reproducing robots, chemical protocells, and hybrid electronic-chemical systems. We define primary (secondary) living technology according as key material components and core systems are not (are) derived from living organisms. Primary living technology is currently emerging, distinctive, and potentially powerful, motivating this review. We trace living technology's connections with artificial life (soft, hard, and wet), synthetic biology (top-down and bottom-up), and the convergence of nano-, bio-, information, and cognitive (NBIC) technologies. We end with a brief look at the social and ethical questions generated by the prospect of living technology.

  5. Final Technical Report - Center for Technology for Advanced Scientific Component Software (TASCS)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sussman, Alan

    2014-10-21

    This is a final technical report for the University of Maryland work in the SciDAC Center for Technology for Advanced Scientific Component Software (TASCS). The Maryland work focused on software tools for coupling parallel software components built using the Common Component Architecture (CCA) APIs. Those tools are based on the Maryland InterComm software framework that has been used in multiple computational science applications to build large-scale simulations of complex physical systems that employ multiple separately developed codes.

  6. Laser rapid forming technology of high-performance dense metal components with complex structure

    NASA Astrophysics Data System (ADS)

    Huang, Weidong; Chen, Jing; Li, Yanming; Lin, Xin

    2005-01-01

    Laser rapid forming (LRF) is a new and advanced manufacturing technology that has been developed on the basis of combining high power laser cladding technology with rapid prototyping (RP) to realize net shape forming of high performance dense metal components without dies. Recently we have developed a set of LRF equipment. LRF experiments were carried out on the equipment to investigate the influences of processing parameters on forming characterizations systematically with the cladding powder materials as titanium alloys, superalloys, stainless steel, and copper alloys. The microstructure of laser formed components is made up of columnar grains or columnar dendrites which grow epitaxially from the substrate since the solid components were prepared layer by layer additionally. The result of mechanical testing proved that the mechanical properties of laser formed samples are similar to or even over that of forging and much better than that of casting. It is shown in this paper that LRF technology is providing a new solution for some difficult processing problems in the high tech field of aviation, spaceflight and automobile industries.

  7. Continuous high speed coherent one-way quantum key distribution.

    PubMed

    Stucki, Damien; Barreiro, Claudio; Fasel, Sylvain; Gautier, Jean-Daniel; Gay, Olivier; Gisin, Nicolas; Thew, Rob; Thoma, Yann; Trinkler, Patrick; Vannel, Fabien; Zbinden, Hugo

    2009-08-03

    Quantum key distribution (QKD) is the first commercial quantum technology operating at the level of single quanta and is a leading light for quantum-enabled photonic technologies. However, controlling these quantum optical systems in real world environments presents significant challenges. For the first time, we have brought together three key concepts for future QKD systems: a simple high-speed protocol; high performance detection; and integration both, at the component level and for standard fibre network connectivity. The QKD system is capable of continuous and autonomous operation, generating secret keys in real time. Laboratory and field tests were performed and comparisons made with robust InGaAs avalanche photodiodes and superconducting detectors. We report the first real world implementation of a fully functional QKD system over a 43 dB-loss (150 km) transmission line in the Swisscom fibre optic network where we obtained average real-time distribution rates over 3 hours of 2.5 bps.

  8. Research and application of key technology of electric submersible plunger pump

    NASA Astrophysics Data System (ADS)

    Qian, K.; Sun, Y. N.; Zheng, S.; Du, W. S.; Li, J. N.; Pei, G. Z.; Gao, Y.; Wu, N.

    2018-06-01

    Electric submersible plunger pump is a new generation of rodless oil production equipment, whose improvements and upgrades of key technologies are conducive to its large-scale application and reduce the cost and improve the efficiency. In this paper, the operating mechanism of the unit in-depth study, aimed at the problems existing in oilfield production, to propose an optimization method creatively, including the optimal design of a linear motor for submersible oil, development of new double-acting load-relief pump, embedded flexible closed-loop control technology, research and development of low-cost power cables. 90 oil wells were used on field application, the average pump inspection cycle is 608 days, the longest pump check cycle has exceeded 1037 days, the average power saving rate is 45.6%. Application results show that the new technology of optimization and upgrading can further improve the reliability and adaptability of electric submersible plunger pump, reduce the cost of investment.

  9. Technological Alternatives to Paper-Based Components of Team-Based Learning

    ERIC Educational Resources Information Center

    Robinson, Daniel H.; Walker, Joshua D.

    2008-01-01

    The authors have been using components of team-based learning (TBL) in two undergraduate courses at the University of Texas for several years: an educational psychology survey course--Cognition, Human Learning and Motivation--and Introduction to Statistics. In this chapter, they describe how they used technology in classes of fifty to seventy…

  10. Academic Technology Transfer: Tracking, Measuring and Enhancing Its Impact

    ERIC Educational Resources Information Center

    Fraser, John

    2010-01-01

    Since the 1980 passage of the US Bayh-Dole Act, academic technology transfer has gained profile globally as a key component of knowledge-driven economic development. Research universities are seen as key contributors. In this article, focusing on the USA and drawing on over twenty years of experience in the field of academic technology transfer in…

  11. An overview of key technology thrusts at Bell Helicopter Textron

    NASA Technical Reports Server (NTRS)

    Harse, James H.; Yen, Jing G.; Taylor, Rodney S.

    1988-01-01

    Insight is provided into several key technologies at Bell. Specific topics include the results of ongoing research and development in advanced rotors, methodology development, and new configurations. The discussion on advanced rotors highlight developments on the composite, bearingless rotor, including the development and testing of full scale flight hardware as well as some of the design support analyses and verification testing. The discussion on methodology development concentrates on analytical development in aeromechanics, including correlation studies and design application. New configurations, presents the results of some advanced configuration studies including hardware development.

  12. Hybrid membrane-microfluidic components using a novel ceramic MEMS technology

    NASA Astrophysics Data System (ADS)

    Lutz, Brent J.; Polyakov, Oleg; Rinaldo, Chris

    2012-03-01

    A novel hybrid nano/microfabrication technology has been employed to produce unique MEMS and microfluidic components that integrate nanoporous membranes. The components are made by micromachining a self-organized nanostructured ceramic material that is biocompatible and amenable to surface chemistry modification. Microfluidic structures, such as channels and wells, can be made with a precision of <2 microns. Thin-film membranes can be integrated into the bottom of these structures, featuring a wide range of possible thicknesses, from 100 micron to <50 nm. Additionally, these membranes may be non-porous or porous (with controllable pore sizes from 200 nm to <5 nm), for sophisticated size-based separations. With previous and current support from the NIH SBIR program, we have built several unique devices, and demonstrated improved separations, cell culturing, and imaging (optical and electron microscopy) versus standard products. Being ceramic, the material is much more robust to demanding environments (e.g. high and low temperatures and organic solvents), compared to polymer-based devices. Additionally, we have applied multiple surface modification techniques, including atomic layer deposition, to manipulate properties such as electrical conductivity. This microfabrication technology is highly scaleable, and thus can yield low-cost, reliable, disposable microcomponents and devices. Specific applications that can benefit from this technology includes cell culturing and assays, imaging by cryo-electron tomography, environmental sample processing, as well as many others.

  13. Advanced Electrical Materials and Components Being Developed

    NASA Technical Reports Server (NTRS)

    Schwarze, Gene E.

    2004-01-01

    All aerospace systems require power management and distribution (PMAD) between the energy and power source and the loads. The PMAD subsystem can be broadly described as the conditioning and control of unregulated power from the energy source and its transmission to a power bus for distribution to the intended loads. All power and control circuits for PMAD require electrical components for switching, energy storage, voltage-to-current transformation, filtering, regulation, protection, and isolation. Advanced electrical materials and component development technology is a key technology to increasing the power density, efficiency, reliability, and operating temperature of the PMAD. The primary means to develop advanced electrical components is to develop new and/or significantly improved electronic materials for capacitors, magnetic components, and semiconductor switches and diodes. The next important step is to develop the processing techniques to fabricate electrical and electronic components that exceed the specifications of presently available state-of-the-art components. The NASA Glenn Research Center's advanced electrical materials and component development technology task is focused on the following three areas: 1) New and/or improved dielectric materials for the development of power capacitors with increased capacitance volumetric efficiency, energy density, and operating temperature; 2) New and/or improved high-frequency, high-temperature soft magnetic materials for the development of transformers and inductors with increased power density, energy density, electrical efficiency, and operating temperature; 3) Packaged high-temperature, high-power density, high-voltage, and low-loss SiC diodes and switches.

  14. Beryllium processing technology review for applications in plasma-facing components

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Castro, R.G.; Jacobson, L.A.; Stanek, P.W.

    1993-07-01

    Materials research and development activities for the International Thermonuclear Experimental Reactor (ITER), i.e., the next generation fusion reactor, are investigating beryllium as the first-wall containment material for the reactor. Important in the selection of beryllium is the ability to process, fabricate and repair beryllium first-wall components using existing technologies. Two issues that will need to be addressed during the engineering design activity will be the bonding of beryllium tiles in high-heat-flux areas of the reactor, and the in situ repair of damaged beryllium tiles. The following review summarizes the current technology associated with welding and joining of beryllium to itselfmore » and other materials, and the state-of-the-art in plasma-spray technology as an in situ repair technique for damaged beryllium tiles. In addition, a review of the current status of beryllium technology in the former Soviet Union is also included.« less

  15. Novel Thin Film Sensor Technology for Turbine Engine Hot Section Components

    NASA Technical Reports Server (NTRS)

    Wrbanek, John D.; Fralick, Gustave C.

    2007-01-01

    Degradation and damage that develops over time in hot section components can lead to catastrophic failure of the turbine section of aircraft engines. A range of thin film sensor technology has been demonstrated enabling on-component measurement of multiple parameters either individually or in sensor arrays including temperature, strain, heat flux, and flow. Conductive ceramics are beginning to be investigated as new materials for use as thin film sensors in the hot section, leveraging expertise in thin films and high temperature materials. The current challenges are to develop new sensor and insulation materials capable of withstanding the extreme hot section environment, and to develop techniques for applying sensors onto complex high temperature structures for aging studies of hot propulsion materials. The technology research and development ongoing at NASA Glenn Research Center for applications to future aircraft, launch vehicles, space vehicles, and ground systems is outlined.

  16. Process technology and effects of spallation products: Circuit components, maintenance, and handling

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sigg, B.; Haines, S.J.; Dressler, R.

    1996-06-01

    Working Session D included an assessment of the status of the technology and components required to: (1) remove impurities from the liquid metal (mercury or Pb-Bi) target flow loop including the effects of spallation products, (2) provide the flow parameters necessary for target operations, and (3) maintain the target system. A series of brief presentations were made to focus the discussion on these issues. The subjects of these presentations, and presenters were: (1) Spallation products and solubilities - R. Dressler; (2) Spallation products for Pb-Bi - Y. Orlov; (3) Clean/up/impurity removal components - B. Sigg; (4) {open_quotes}Road-Map{close_quotes} and remote handlingmore » needs - T. McManamy; (5) Remote handling issues and development - M. Holding. The overall conclusion of this session was that, with the exception of (i) spallation product related processing issues, (ii) helium injection and clean-up, and (iii) specialized remote handling equipment, the technology for all other circuit components (excluding the target itself) exists. Operating systems at the Institute of Physics in Riga, Latvia (O. Lielausis) and at Ben-Gurion University in Beer Shiva, Israel (S. Lesin) have demonstrated that other liquid metal circuit components including pumps, heat exchangers, valves, seals, and piping are readily available and have been reliably used for many years. In the three areas listed above, the designs and analysis are not judged to be mature enough to determine whether and what types of technology development are required. Further design and analysis of the liquid metal target system is therefore needed to define flow circuit processing and remote handling equipment requirements and thereby identify any development needs.« less

  17. NASA JPL Distributed Systems Technology (DST) Object-Oriented Component Approach for Software Inter-Operability and Reuse

    NASA Technical Reports Server (NTRS)

    Hall, Laverne; Hung, Chaw-Kwei; Lin, Imin

    2000-01-01

    The purpose of this paper is to provide a description of NASA JPL Distributed Systems Technology (DST) Section's object-oriented component approach to open inter-operable systems software development and software reuse. It will address what is meant by the terminology object component software, give an overview of the component-based development approach and how it relates to infrastructure support of software architectures and promotes reuse, enumerate on the benefits of this approach, and give examples of application prototypes demonstrating its usage and advantages. Utilization of the object-oriented component technology approach for system development and software reuse will apply to several areas within JPL, and possibly across other NASA Centers.

  18. A Resource Guide Identifying Technology Tools for Schools. Appendix

    ERIC Educational Resources Information Center

    Fox, Christine; Jones, Rachel

    2009-01-01

    SETDA and NASTID's "Technology Tools for Schools Resource Guide" provides definitions of key technology components and relevant examples, where appropriate as a glossary for educators. The guide also presents essential implementation and infrastructure considerations that decision makers should think about when implementing technology in schools.…

  19. The enabling technology for recovery of valued components from minerals in the upper and Mid Amur region

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sorokin, A.P.; Rimkevich, V.S.; Dem'yanova, L.P.

    2009-05-15

    Based on the physico-technical operations involved in the mineral processing technologies, the optimal production conditions are found for refractory fiber materials, aluminium, silicium, their compounds and other valued components. Ecologically safe and efficient aggregate technologies are developed for recovery of valued components from nonmetallic minerals and anthracides (brown coals).

  20. Component technology for space power systems

    NASA Technical Reports Server (NTRS)

    Finke, R. C.

    1982-01-01

    Progress made by NASA toward implementation of equipment for the conversion, management, and distribution of voltage power in space applications are reviewed. Work has been carried forward on components such as bipolar transistors, deep impurity semiconductors, conductors, dielectrics, magnetic devices, and rotary power transfer. Specific programs for the high voltage systems have included research on lightweight, low-cost conductors featuring graphite fibers containing electron donor materials for wires and cables with reduced mass and the conductivity of copper. Attention has also been given p-n junction technology for high-speed, high-current, high-voltage materials and diamond-like dielectric films which are hard, have high dielectric strength, and can operate up to 300 C. A transistor has been fabricated with a voltage of 1200 V at 100 A, with a gain of 10 and a 0.5 microsec rise/fall time. A 25 kW transformer has also been built which performs at 20 kHz with an efficiency of 99.2%.

  1. Component technology for space power systems

    NASA Technical Reports Server (NTRS)

    Finke, R.

    1982-01-01

    The Lewis/OAST program for the development of Component Technology for Space Power Systems is described. The program is divided into five generic areas: semiconductor devices (transistors, thyristors, and diodes); conductors (materials and transmission lines); dielectrics; magnetic devices; and thermal control devices. Examples of progress in each of the five areas is discussed. Bipolar power transistors up to 1000 V at 100 A with a gain of 10 and a 0.5 mu sec rise and fall time are presented. A new class of semiconductor devices with a possibility of switching 1000 000 V is described. Several 100 kW rotary power transformer designs and a 25 kW, 20 kHz transformer weighting 3.2 kg have been developed. Progress on the creation of diamond-like films for thermal devices and intercalated carbon fibers with the strength of steel and the conductivity of copper at one third the mass of copper is presented.

  2. [Discussion on appraisal methods and key technologies of arbuscular mycorrhizal fungi and medicinal plant symbiosis system].

    PubMed

    Chen, Meilan; Guo, Lanping; Yang, Guang; Chen, Min; Yang, Li; Huang, Luqi

    2011-11-01

    Applications of arbuscular mycorrhizal fungi in research of medicinal plant cultivation are increased in recent years. Medicinal plants habitat is complicated and many inclusions are in root, however crop habitat is simple and few inclusions in root. So appraisal methods and key technologies about the symbiotic system of crop and arbuscular mycorrhizal fungi can't completely suitable for the symbiotic system of medicinal plants and arbuscular mycorrhizal fungi. This article discuss the appraisal methods and key technologies about the symbiotic system of medicinal plant and arbuscular mycorrhizal fungi from the isolation and identification of arbuscular mycorrhiza, and the appraisal of colonization intensity. This article provides guidance for application research of arbuscular mycorrhizal fungi in cultivation of medicinal plants.

  3. A Future Large-Aperture UVOIR Space Observatory: Key Technologies and Capabilities

    NASA Technical Reports Server (NTRS)

    Bolcar, Matthew Ryan; Stahle, Carl M.; Balasubramaniam, Kunjithapatham; Clampin, Mark; Feinberg, Lee D.; Mosier, Gary E.; Quijada, Manuel A.; Rauscher, Bernard J.; Redding, David C.; Rioux, Norman M.; hide

    2015-01-01

    We present the key technologies and capabilities that will enable a future, large-aperture ultravioletopticalinfrared (UVOIR) space observatory. These include starlight suppression systems, vibration isolation and control systems, lightweight mirror segments, detector systems, and mirror coatings. These capabilities will provide major advances over current and near-future observatories for sensitivity, angular resolution, and starlight suppression. The goals adopted in our study for the starlight suppression system are 10-10 contrast with an inner working angle of 20 milliarcsec and broad bandpass. We estimate that a vibration and isolation control system that achieves a total system vibration isolation of 140 dB for a vibration-isolated mass of 5000 kg is required to achieve the high wavefront error stability needed for exoplanet coronagraphy. Technology challenges for lightweight mirror segments include diffraction-limited optical quality and high wavefront error stability as well as low cost, low mass, and rapid fabrication. Key challenges for the detector systems include visible-blind, high quantum efficiency UV arrays, photon counting visible and NIR arrays for coronagraphic spectroscopy and starlight wavefront sensing and control, and detectors with deep full wells with low persistence and radiation tolerance to enable transit imaging and spectroscopy at all wavelengths. Finally, mirror coatings with high reflectivity ( 90), high uniformity ( 1) and low polarization ( 1) that are scalable to large diameter mirror substrates will be essential for ensuring that both high throughput UV observations and high contrast observations can be performed by the same observatory.

  4. Development of structural ceramic components for automobile applications

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kawamoto, H.

    1995-12-01

    Development efforts have been made in automobile technologies on heat engines to improve the power performance, the fuel economy, and so on. It is well recognized that ceramic applications are keys to succeed in such advanced heat engines, because of their good mechanical and thermal properties. This paper discusses present automobile applications of structural ceramic components and the expectations in automobile uses. The strength and reliability of mass-produced components for the engines are described with the manufacturing processes. The future R&D directions are recommended for structural ceramics.

  5. The Prediction of Key Cytoskeleton Components Involved in Glomerular Diseases Based on a Protein-Protein Interaction Network.

    PubMed

    Ding, Fangrui; Tan, Aidi; Ju, Wenjun; Li, Xuejuan; Li, Shao; Ding, Jie

    2016-01-01

    Maintenance of the physiological morphologies of different types of cells and tissues is essential for the normal functioning of each system in the human body. Dynamic variations in cell and tissue morphologies depend on accurate adjustments of the cytoskeletal system. The cytoskeletal system in the glomerulus plays a key role in the normal process of kidney filtration. To enhance the understanding of the possible roles of the cytoskeleton in glomerular diseases, we constructed the Glomerular Cytoskeleton Network (GCNet), which shows the protein-protein interaction network in the glomerulus, and identified several possible key cytoskeletal components involved in glomerular diseases. In this study, genes/proteins annotated to the cytoskeleton were detected by Gene Ontology analysis, and glomerulus-enriched genes were selected from nine available glomerular expression datasets. Then, the GCNet was generated by combining these two sets of information. To predict the possible key cytoskeleton components in glomerular diseases, we then examined the common regulation of the genes in GCNet in the context of five glomerular diseases based on their transcriptomic data. As a result, twenty-one cytoskeleton components as potential candidate were highlighted for consistently down- or up-regulating in all five glomerular diseases. And then, these candidates were examined in relation to existing known glomerular diseases and genes to determine their possible functions and interactions. In addition, the mRNA levels of these candidates were also validated in a puromycin aminonucleoside(PAN) induced rat nephropathy model and were also matched with existing Diabetic Nephropathy (DN) transcriptomic data. As a result, there are 15 of 21 candidates in PAN induced nephropathy model were consistent with our predication and also 12 of 21 candidates were matched with differentially expressed genes in the DN transcriptomic data. By providing a novel interaction network and prediction, GCNet

  6. The Prediction of Key Cytoskeleton Components Involved in Glomerular Diseases Based on a Protein-Protein Interaction Network

    PubMed Central

    Ju, Wenjun; Li, Xuejuan; Li, Shao; Ding, Jie

    2016-01-01

    Maintenance of the physiological morphologies of different types of cells and tissues is essential for the normal functioning of each system in the human body. Dynamic variations in cell and tissue morphologies depend on accurate adjustments of the cytoskeletal system. The cytoskeletal system in the glomerulus plays a key role in the normal process of kidney filtration. To enhance the understanding of the possible roles of the cytoskeleton in glomerular diseases, we constructed the Glomerular Cytoskeleton Network (GCNet), which shows the protein-protein interaction network in the glomerulus, and identified several possible key cytoskeletal components involved in glomerular diseases. In this study, genes/proteins annotated to the cytoskeleton were detected by Gene Ontology analysis, and glomerulus-enriched genes were selected from nine available glomerular expression datasets. Then, the GCNet was generated by combining these two sets of information. To predict the possible key cytoskeleton components in glomerular diseases, we then examined the common regulation of the genes in GCNet in the context of five glomerular diseases based on their transcriptomic data. As a result, twenty-one cytoskeleton components as potential candidate were highlighted for consistently down- or up-regulating in all five glomerular diseases. And then, these candidates were examined in relation to existing known glomerular diseases and genes to determine their possible functions and interactions. In addition, the mRNA levels of these candidates were also validated in a puromycin aminonucleoside(PAN) induced rat nephropathy model and were also matched with existing Diabetic Nephropathy (DN) transcriptomic data. As a result, there are 15 of 21 candidates in PAN induced nephropathy model were consistent with our predication and also 12 of 21 candidates were matched with differentially expressed genes in the DN transcriptomic data. By providing a novel interaction network and prediction, GCNet

  7. An overview of the Small Engine Component Technology (SECT) studies

    NASA Technical Reports Server (NTRS)

    Vanco, M. R.; Wintucky, W. T.; Niedzwiecki, R. W.

    1986-01-01

    The objectives of the joint NASA/Army SECT Studies were to identify high payoff technologies for year 2000 small gas turbine engine applications and to provide a technology plan for guiding future research and technology efforts applicable to rotorcraft, commuter and general aviation aircraft and cruise missiles. Competitive contracts were awarded to Allison, AVCO Lycoming, Garrett, Teledyne CAE and Williams International. This paper presents an overview of the contractors' study efforts for the commuter, rotorcraft, cruise missile, and auxiliary power (APU) applications with engines in the 250 to 1,000 horsepower size range. Reference aircraft, missions and engines were selected. Advanced engine configurations and cycles with projected year 2000 component technologies were evaluated and compared with a reference engine selected by the contractor. For typical commuter and rotorcraft applications, fuel savings of 22 percent to 42 percent can be attained. For $1/gallon and $2/gallon fuel, reductions in direct operating cost range from 6 percent to 16 percent and from 11 percent to 17 percent respectively. For subsonic strategic cruise missile applications, fuel savings of 38 percent to 54 percent can be achieved which allows 35 percent to 60 percent increase in mission range and life cycle cost reductions of 40 percent to 56 percent. High payoff technologies have been identified for all applications.

  8. Ineffective Healthcare Technology Management in Benin’s Public Health Sector: The Perceptions of Key Actors and Their Ability to Address the Main Problems

    PubMed Central

    Houngbo, P. Thierry; De Cock Buning, Tjard; Bunders, Joske; Coleman, Harry L. S.; Medenou, Daton; Dakpanon, Laurent; Zweekhorst, Marjolein

    2017-01-01

    Background: Low-income countries face many contextual challenges to manage healthcare technologies effectively, as the majority are imported and resources are constrained to a greater extent. Previous healthcare technology management (HTM) policies in Benin have failed to produce better quality of care for the population and costeffectiveness for the government. This study aims to identify and assess the main problems facing HTM in Benin’s public health sector, as well as the ability of key actors within the sector to address these problems. Methods: We conducted 2 surveys in 117 selected health facilities. The first survey was based on 377 questionnaires and 259 interviews, and the second involved observation and group interviews at health facilities. The Temple-Bird Healthcare Technology Package System (TBHTPS), tailored to the context of Benin’s health system, was used as a conceptual framework. Results: The findings of the first survey show that 85% of key actors in Benin’s HTM sector characterized the system as failing in components of the TBHTPS framework. Biomedical, clinical, healthcare technology engineers and technicians perceived problems most severely, followed by users of equipment, managers and hospital directors, international organization officers, local and foreign suppliers, and finally policy-makers, planners and administrators at the Ministry of Health (MoH). The 5 most important challenges to be addressed are policy, strategic management and planning, and technology needs assessment and selection – categorized as major enabling inputs (MEI) in HTM by the TBHTPS framework – and installation and commissioning, training and skill development and procurement, which are import and use activities (IUA). The ability of each key actor to address these problems (the degree of political or administrative power they possess) was inversely proportional to their perception of the severity of the problems. Observational data gathered during site

  9. The NASA research and technology program on space power: A key element of the Space Exploration Initiative

    NASA Technical Reports Server (NTRS)

    Bennett, Gary L.; Brandhorst, Henry W., Jr.; Atkins, Kenneth L.

    1991-01-01

    In July 1989, President Bush announced his space exploration initiative of going back to the Moon to stay and then going to Mars. Building upon its ongoing research and technology base, NASA has established an exploration technology program to develop the technologies needed for piloted missions to the Moon and Mars. A key element for the flights and for the planned bases is power. The NASA research and technology program on space power encompasses power sources, energy storage, and power management.

  10. Intermediate experimental vehicle, ESA program aerodynamics-aerothermodynamics key technologies for spacecraft design and successful flight

    NASA Astrophysics Data System (ADS)

    Dutheil, Sylvain; Pibarot, Julien; Tran, Dac; Vallee, Jean-Jacques; Tribot, Jean-Pierre

    2016-07-01

    With the aim of placing Europe among the world's space players in the strategic area of atmospheric re-entry, several studies on experimental vehicle concepts and improvements of critical re-entry technologies have paved the way for the flight of an experimental space craft. The successful flight of the Intermediate eXperimental Vehicle (IXV), under ESA's Future Launchers Preparatory Programme (FLPP), is definitively a significant step forward from the Atmospheric Reentry Demonstrator flight (1998), establishing Europe as a key player in this field. The IXV project objectives were the design, development, manufacture and ground and flight verification of an autonomous European lifting and aerodynamically controlled reentry system, which is highly flexible and maneuverable. The paper presents, the role of aerodynamics aerothermodynamics as part of the key technologies for designing an atmospheric re-entry spacecraft and securing a successful flight.

  11. Research and Implementation of Key Technologies in Multi-Agent System to Support Distributed Workflow

    NASA Astrophysics Data System (ADS)

    Pan, Tianheng

    2018-01-01

    In recent years, the combination of workflow management system and Multi-agent technology is a hot research field. The problem of lack of flexibility in workflow management system can be improved by introducing multi-agent collaborative management. The workflow management system adopts distributed structure. It solves the problem that the traditional centralized workflow structure is fragile. In this paper, the agent of Distributed workflow management system is divided according to its function. The execution process of each type of agent is analyzed. The key technologies such as process execution and resource management are analyzed.

  12. Research on key technology of planning and design for AC/DC hybrid distribution network

    NASA Astrophysics Data System (ADS)

    Shen, Yu; Wu, Guilian; Zheng, Huan; Deng, Junpeng; Shi, Pengjia

    2018-04-01

    With the increasing demand of DC generation and DC load, the development of DC technology, AC and DC distribution network integrating will become an important form of future distribution network. In this paper, the key technology of planning and design for AC/DC hybrid distribution network is proposed, including the selection of AC and DC voltage series, the design of typical grid structure and the comprehensive evaluation method of planning scheme. The research results provide some ideas and directions for the future development of AC/DC hybrid distribution network.

  13. "Handy Manny" and the Emergent Literacy Technology Toolkit

    ERIC Educational Resources Information Center

    Hourcade, Jack J.; Parette, Howard P., Jr.; Boeckmann, Nichole; Blum, Craig

    2010-01-01

    This paper outlines the use of a technology toolkit to support emergent literacy curriculum and instruction in early childhood education settings. Components of the toolkit include hardware and software that can facilitate key emergent literacy skills. Implementation of the comprehensive technology toolkit enhances the development of these…

  14. Results from the electro-optic sensors domain of the materials and components for missiles innovation and technology partnership (phase 1)

    NASA Astrophysics Data System (ADS)

    Bray, Mark E.; Shears, Robert A.

    2013-10-01

    The Materials and Components for Missiles Innovation and Technology Partnership (ITP) is a research programme supporting research for guided weapons at Technology Readiness Levels 1 to 4. The Anglo-French initiative is supported by the DGA and the MoD, with matched funding from industry. A major objective is to foster projects which partner UK and French universities, SMEs and larger companies. The first projects started in January 2008 and the first phase completed in spring 2013. Providing funding is secured, the next phase of the programme is due to start later in 2013. Selex ES leads Domain 3 of the MCM-ITP which develops Electro-Optic sensor technology. In collaboration with DGA, MoD and MBDA, the prime contractor, we identified 4 key objectives for the first ITP phase and focussed resources on achieving these. The objectives were to enable better imagery, address operationally stressing scenarios, provide low overall through life cost and improve active and semi-active sensors Nine normal projects and one ITP innovation fund project have been supported within the domain. The technology providers have included 3 SMEs and 8 research centres from both the United Kingdom and France. Highlights of the projects are included. An outline of the priorities for the domain for the new phase ise provided and we encourage organisations with suitable technology to contact us to get involved.

  15. Evaluation of the Introduction of an e-Health Skills Component for Dietetics Students.

    PubMed

    Rollo, Megan E; Collins, Clare E; MacDonald-Wicks, Lesley

    2017-11-01

    Appropriate and effective use of technology within practice is a key competency outlined in Australian dietetics training standards. An e-health skills component (lecture and workshop) was introduced to undergraduate students enrolled in an Australian nutrition and dietetics program. The lecture orientated students to key e-health terms and concepts relating to telehealth and m-health technologies, while the workshop provided an opportunity to apply knowledge. The workshop consisted of four stations with activities relating to (1) orientation to telehealth equipment; (2) comparison of dietetic consultation components completed in person versus remotely via video call; (3) quality assessment of mobile apps; and (4) exploration of advantages and disadvantages, and the ethical, security, and privacy issues relating to use of e-health technologies in dietetic practice. Student experience of the training was evaluated via questionnaire. Forty-five students (62.2% aged ≤19-24 years, 86.7% female) completed the survey. Following the workshop, the level of understanding relating to each key e-health concept improved significantly (p < 0.001). The aspects relating to the impact and need for initial training and ongoing professional education to support the use of e-health technologies within dietetic practice were rated a high level of importance by most students (78-80%). The majority of students (93.3% to 97.8%) reported a positive experience at each of the four workshop stations, with "informative" the most common word selected to rate each station (37.8% to 44.4% of students across the four stations). The introduction of an e-health skills component resulted in an improved understanding of concepts for using these technologies. These findings provide preliminary support for integration of further e-health training within the dietetics program.

  16. Some legal, jurisdictional, and operational implications of a congressional technology assessment component

    NASA Technical Reports Server (NTRS)

    Mayo, L. H.

    1975-01-01

    An analysis is presented for the Congress of the relationships between an institutionalized assessment function and legislative information gathering and decisionmaking needs. The study was directed to the following topics: (1) the positing of a hypothetical technology assessment component for legislative support; (2) the posing of a number of questions relating to the operational context of this assessment component including the organization/operational framework, general operational problems, access to relevant information, and the utilization of assessment data and analyses; and (3) some selected comments relevant to the questions posed.

  17. Research of the key technology in satellite communication networks

    NASA Astrophysics Data System (ADS)

    Zeng, Yuan

    2018-02-01

    According to the prediction, in the next 10 years the wireless data traffic will be increased by 500-1000 times. Not only the wireless data traffic will be increased exponentially, and the demand for diversified traffic will be increased. Higher requirements for future mobile wireless communication system had brought huge market space for satellite communication system. At the same time, the space information networks had been greatly developed with the depth of human exploration of space activities, the development of space application, the expansion of military and civilian application. The core of spatial information networks is the satellite communication. The dissertation presented the communication system architecture, the communication protocol, the routing strategy, switch scheduling algorithm and the handoff strategy based on the satellite communication system. We built the simulation platform of the LEO satellites networks and simulated the key technology using OPNET.

  18. Template identification technology of nuclear warheads and components

    NASA Astrophysics Data System (ADS)

    Liu, Su-Ping; Gong, Jian; Hao, Fan-Hua; Hu, Guang-Chun

    2008-02-01

    Template identification technology (TIT) is designed for the scenarios where a batch of disarmed nuclear weapons or components would be dismantled to observe a nuclear disarmament treaty. The core function played by the TIT is to make a judgment on whether the verified item belongs to a certain kind of nuclear weapons or component (NW/NC) or to which kind the verified item belongs. This paper analyses the functions played by the TIT in the process of NW/NC dismantlement, and proposes that two phases would be followed when applying the TIT: firstly to establish NW/NC templates with a sample of size n drawn from a certain kind of disarmament NW; secondly to authenticate NW/NC by means of the TIT. This paper also expatiates some terms related to the concept of the TIT and investigates on the development status of NW/NC TIT based on radiation signatures. The study concludes that the design of template structure is crucial to the establishment of an effective TIT and that starting from different research angles and aiming at the same goal of classification different template structures and corresponding template identification methods can be built up to meet specific identification requirements.

  19. [Identification of antler powder components based on DNA barcoding technology].

    PubMed

    Jia, Jing; Shi, Lin-chun; Xu, Zhi-chao; Xin, Tian-yi; Song, Jing-yuan; Chen Shi, Lin

    2015-10-01

    In order to authenticate the components of antler powder in the market, DNA barcoding technology coupled with cloning method were used. Cytochrome c oxidase subunit I (COI) sequences were obtained according to the DNA barcoding standard operation procedure (SOP). For antler powder with possible mixed components, the cloning method was used to get each COI sequence. 65 COI sequences were successfully obtained from commercial antler powders via sequencing PCR products. The results indicates that only 38% of these samples were derived from Cervus nippon Temminck or Cervus elaphus Linnaeus which is recorded in the 2010 edition of "Chinese Pharmacopoeia", while 62% of them were derived from other species. Rangifer tarandus Linnaeus was the most frequent species among the adulterants. Further analysis showed that some samples collected from different regions, companies and prices, contained adulterants. Analysis of 36 COI sequences obtained by the cloning method showed that C. elaphus and C. nippon were main components. In addition, some samples were marked clearly as antler powder on the label, however, C. elaphus or R. tarandus were their main components. In summary, DNA barcoding can accurately and efficiently distinguish the exact content in the commercial antler powder, which provides a new technique to ensure clinical safety and improve quality control of Chinese traditional medicine

  20. Research on Key Technologies of Cloud Computing

    NASA Astrophysics Data System (ADS)

    Zhang, Shufen; Yan, Hongcan; Chen, Xuebin

    With the development of multi-core processors, virtualization, distributed storage, broadband Internet and automatic management, a new type of computing mode named cloud computing is produced. It distributes computation task on the resource pool which consists of massive computers, so the application systems can obtain the computing power, the storage space and software service according to its demand. It can concentrate all the computing resources and manage them automatically by the software without intervene. This makes application offers not to annoy for tedious details and more absorbed in his business. It will be advantageous to innovation and reduce cost. It's the ultimate goal of cloud computing to provide calculation, services and applications as a public facility for the public, So that people can use the computer resources just like using water, electricity, gas and telephone. Currently, the understanding of cloud computing is developing and changing constantly, cloud computing still has no unanimous definition. This paper describes three main service forms of cloud computing: SAAS, PAAS, IAAS, compared the definition of cloud computing which is given by Google, Amazon, IBM and other companies, summarized the basic characteristics of cloud computing, and emphasized on the key technologies such as data storage, data management, virtualization and programming model.

  1. Designing components using smartMOVE electroactive polymer technology

    NASA Astrophysics Data System (ADS)

    Rosenthal, Marcus; Weaber, Chris; Polyakov, Ilya; Zarrabi, Al; Gise, Peter

    2008-03-01

    Designing components using SmartMOVE TM electroactive polymer technology requires an understanding of the basic operation principles and the necessary design tools for integration into actuator, sensor and energy generation applications. Artificial Muscle, Inc. is collaborating with OEMs to develop customized solutions for their applications using smartMOVE. SmartMOVE is an advanced and elegant way to obtain almost any kind of movement using dielectric elastomer electroactive polymers. Integration of this technology offers the unique capability to create highly precise and customized motion for devices and systems that require actuation. Applications of SmartMOVE include linear actuators for medical, consumer and industrial applications, such as pumps, valves, optical or haptic devices. This paper will present design guidelines for selecting a smartMOVE actuator design to match the stroke, force, power, size, speed, environmental and reliability requirements for a range of applications. Power supply and controller design and selection will also be introduced. An overview of some of the most versatile configuration options will be presented with performance comparisons. A case example will include the selection, optimization, and performance overview of a smartMOVE actuator for the cell phone camera auto-focus and proportional valve applications.

  2. Three-Dimensional Integrated Circuit (3D IC) Key Technology: Through-Silicon Via (TSV).

    PubMed

    Shen, Wen-Wei; Chen, Kuan-Neng

    2017-12-01

    3D integration with through-silicon via (TSV) is a promising candidate to perform system-level integration with smaller package size, higher interconnection density, and better performance. TSV fabrication is the key technology to permit communications between various strata of the 3D integration system. TSV fabrication steps, such as etching, isolation, metallization processes, and related failure modes, as well as other characterizations are discussed in this invited review paper.

  3. Research on key technologies for data-interoperability-based metadata, data compression and encryption, and their application

    NASA Astrophysics Data System (ADS)

    Yu, Xu; Shao, Quanqin; Zhu, Yunhai; Deng, Yuejin; Yang, Haijun

    2006-10-01

    With the development of informationization and the separation between data management departments and application departments, spatial data sharing becomes one of the most important objectives for the spatial information infrastructure construction, and spatial metadata management system, data transmission security and data compression are the key technologies to realize spatial data sharing. This paper discusses the key technologies for metadata based on data interoperability, deeply researches the data compression algorithms such as adaptive Huffman algorithm, LZ77 and LZ78 algorithm, studies to apply digital signature technique to encrypt spatial data, which can not only identify the transmitter of spatial data, but also find timely whether the spatial data are sophisticated during the course of network transmission, and based on the analysis of symmetric encryption algorithms including 3DES,AES and asymmetric encryption algorithm - RAS, combining with HASH algorithm, presents a improved mix encryption method for spatial data. Digital signature technology and digital watermarking technology are also discussed. Then, a new solution of spatial data network distribution is put forward, which adopts three-layer architecture. Based on the framework, we give a spatial data network distribution system, which is efficient and safe, and also prove the feasibility and validity of the proposed solution.

  4. Small Engine Component Technology (SECT)

    NASA Technical Reports Server (NTRS)

    Early, M.; Dawson, R.; Zeiner, P.; Turk, M.; Benn, K.

    1986-01-01

    A study of small gas turbine engines was conducted to identify high payoff technologies for year-2000 engines and to define companion technology plans. The study addressed engines in the 186 to 746 KW (250 to 1000 shp) or equivalent thrust range for rotorcraft, commuter (turboprop), cruise missile (turbojet), and APU applications. The results show that aggressive advancement of high payoff technologies can produce significant benefits, including reduced SFC, weight, and cost for year-2000 engines. Mission studies for these engines show potential fuel burn reductions of 22 to 71 percent. These engine benefits translate into reductions in rotorcraft and commuter aircraft direct operating costs (DOC) of 7 to 11 percent, and in APU-related DOCs of 37 to 47 percent. The study further shows that cruise missile range can be increased by as much as 200 percent (320 percent with slurry fuels) for a year-2000 missile-turbojet system compared to a current rocket-powered system. The high payoff technologies were identified and the benefits quantified. Based on this, technology plans were defined for each of the four engine applications as recommended guidelines for further NASA research and technology efforts to establish technological readiness for the year 2000.

  5. The Development Status and Key Technologies of Solar Powered Unmanned Air Vehicle

    NASA Astrophysics Data System (ADS)

    Sai, Li; Wei, Zhou; Xueren, Wang

    2017-03-01

    By analyzing the development status of several typical solar powered unmanned aerial vehicles (UAV) at home and abroad, the key technologies involved in the design and manufacture of solar powered UAV and the technical difficulties need to be solved at present are obtained. It is pointed out that with the improvement of energy system efficiency, advanced aerodynamic configuration design, realization of high applicability flight stability and control system, breakthrough of efficient propulsion system, the application prospect of solar powered UAV will be more extensive.

  6. Photonics technology development for optical fuzing.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Liu, J.J.; Geib, Kent Martin; von der Lippe, C.M.

    2005-07-01

    This paper describes the photonic component development, which exploits pioneering work and unique expertise at Sandia National Laboratories, ARDEC and the Army Research Laboratory by combining key optoelectronic technologies to design and demonstrate components for this fuzing application. The technologies under investigation for the optical fuze design covered in this paper are vertical cavity surface emitting lasers (VECSELs), integrated resonant cavity photodetectors (RCPD), and diffractive micro-optics. The culmination of this work will be low cost, robust, fully integrated, g-hardened components designed suitable for proximity fuzing applications. The use of advanced photonic components will enable replacement of costly assemblies that employmore » discrete lasers, photodetectors, and bulk optics. The integrated devices will be mass produced and impart huge savings for a variety of Army applications.« less

  7. Capturing how age-friendly communities foster positive health, social participation and health equity: a study protocol of key components and processes that promote population health in aging Canadians.

    PubMed

    Levasseur, Mélanie; Dubois, Marie-France; Généreux, Mélissa; Menec, Verena; Raina, Parminder; Roy, Mathieu; Gabaude, Catherine; Couturier, Yves; St-Pierre, Catherine

    2017-05-25

    To address the challenges of the global aging population, the World Health Organization promoted age-friendly communities as a way to foster the development of active aging community initiatives. Accordingly, key components (i.e., policies, services and structures related to the communities' physical and social environments) should be designed to be age-friendly and help all aging adults to live safely, enjoy good health and stay involved in their communities. Although age-friendly communities are believed to be a promising way to help aging Canadians lead healthy and active lives, little is known about which key components best foster positive health, social participation and health equity, and their underlying mechanisms. This study aims to better understand which and how key components of age-friendly communities best foster positive health, social participation and health equity in aging Canadians. Specifically, the research objectives are to: 1) Describe and compare age-friendly key components of communities across Canada 2) Identify key components best associated with positive health, social participation and health equity of aging adults 3) Explore how these key components foster positive health, social participation and health equity METHODS: A mixed-method sequential explanatory design will be used. The quantitative part will involve a survey of Canadian communities and secondary analysis of cross-sectional data from the Canadian Longitudinal Study on Aging (CLSA). The survey will include an age-friendly questionnaire targeting key components in seven domains: physical environment, housing options, social environment, opportunities for participation, community supports and healthcare services, transportation options, communication and information. The CLSA is a large, national prospective study representative of the Canadian aging population designed to examine health transitions and trajectories of adults as they age. In the qualitative part, a multiple

  8. Stakeholder engagement: a key component of integrating genomic information into electronic health records

    PubMed Central

    Hartzler, Andrea; McCarty, Catherine A.; Rasmussen, Luke V.; Williams, Marc S.; Brilliant, Murray; Bowton, Erica A.; Clayton, Ellen Wright; Faucett, William A.; Ferryman, Kadija; Field, Julie R.; Fullerton, Stephanie M.; Horowitz, Carol R.; Koenig, Barbara A.; McCormick, Jennifer B.; Ralston, James D.; Sanderson, Saskia C.; Smith, Maureen E.; Trinidad, Susan Brown

    2014-01-01

    Integrating genomic information into clinical care and the electronic health record can facilitate personalized medicine through genetically guided clinical decision support. Stakeholder involvement is critical to the success of these implementation efforts. Prior work on implementation of clinical information systems provides broad guidance to inform effective engagement strategies. We add to this evidence-based recommendations that are specific to issues at the intersection of genomics and the electronic health record. We describe stakeholder engagement strategies employed by the Electronic Medical Records and Genomics Network, a national consortium of US research institutions funded by the National Human Genome Research Institute to develop, disseminate, and apply approaches that combine genomic and electronic health record data. Through select examples drawn from sites of the Electronic Medical Records and Genomics Network, we illustrate a continuum of engagement strategies to inform genomic integration into commercial and homegrown electronic health records across a range of health-care settings. We frame engagement as activities to consult, involve, and partner with key stakeholder groups throughout specific phases of health information technology implementation. Our aim is to provide insights into engagement strategies to guide genomic integration based on our unique network experiences and lessons learned within the broader context of implementation research in biomedical informatics. On the basis of our collective experience, we describe key stakeholder practices, challenges, and considerations for successful genomic integration to support personalized medicine. PMID:24030437

  9. The Changing Shape of Technology on Campus from Ermergence to Convergence.

    ERIC Educational Resources Information Center

    Cunningham, Kevin; Rainey, Sylvia

    2001-01-01

    Explores the basics in technology convergence in making today's college and university campuses more "intelligent." Two key components required for effective technology convergence are described as are the benefits of convergence on campus safety and security and utility cost management. (GR)

  10. Seal Technology Development for Advanced Component for Airbreathing Engines

    NASA Technical Reports Server (NTRS)

    Snyder, Philip H.

    2008-01-01

    Key aspects of the design of sealing systems for On Rotor Combustion/Wave Rotor (ORC/WR) systems were addressed. ORC/WR systems generally fit within a broad class of pressure gain Constant Volume Combustors (CVCs) or Pulse Detonation Combustors (PDCs) which are currently being considered for use in many classes of turbine engines for dramatic efficiency improvement. Technology readiness level of this ORC/WR approaches are presently at 2.0. The results of detailed modeling of an ORC/WR system as applied to a regional jet engine application were shown to capture a high degree of pressure gain capabilities. The results of engine cycle analysis indicated the level of specific fuel consumption (SFC) benefits to be 17 percent. The potential losses in pressure gain due to leakage were found to be closely coupled to the wave processes at the rotor endpoints of the ORC/WR system. Extensive investigation into the sealing approaches is reported. Sensitivity studies show that SFC gains of 10 percent remain available even when pressure gain levels are highly penalized. This indicates ORC/WR systems to have a high degree of tolerance to rotor leakage effects but also emphasizes their importance. An engine demonstration of an ORC/WR system is seen as key to progressing the TRL of this technology. An industrial engine was judged to be a highly advantageous platform for demonstration of a first generation ORC/WR system. Prior to such a demonstration, the existing NASA pressure exchanger wave rotor rig was identified as an opportunity to apply both expanded analytical modeling capabilities developed within this program and to identify and fix identified leakage issues existing within this rig. Extensive leakage analysis of the rig was performed and a detailed design of additional sealing strategies for this rig was generated.

  11. Considering Components, Types, and Degrees of Authenticity in Designing Technology to Support Transfer

    ERIC Educational Resources Information Center

    Hardre, Patricia L.

    2013-01-01

    Authenticity is a key to using technology for instruction in ways that enhance learning and support learning transfer. Simply put, a representation is authentic when it shows learners clearly what a task, context, or experience will be like in real practice. More authentic representations help people learn and understand better. They support…

  12. Assessment of technological level of stem cell research using principal component analysis.

    PubMed

    Do Cho, Sung; Hwan Hyun, Byung; Kim, Jae Kyeom

    2016-01-01

    In general, technological levels have been assessed based on specialist's opinion through the methods such as Delphi. But in such cases, results could be significantly biased per study design and individual expert. In this study, therefore scientific literatures and patents were selected by means of analytic indexes for statistic approach and technical assessment of stem cell fields. The analytic indexes, numbers and impact indexes of scientific literatures and patents, were weighted based on principal component analysis, and then, were summated into the single value. Technological obsolescence was calculated through the cited half-life of patents issued by the United States Patents and Trademark Office and was reflected in technological level assessment. As results, ranks of each nation's in reference to the technology level were rated by the proposed method. Furthermore we were able to evaluate strengthens and weaknesses thereof. Although our empirical research presents faithful results, in the further study, there is a need to compare the existing methods and the suggested method.

  13. Imaging Exoplanets with the Exo-S Starshade Mission: Key Enabling Technologies

    NASA Astrophysics Data System (ADS)

    Kasdin, N. Jeremy; Lisman, Doug; Shaklan, Stuart; Thomson, Mark; Webb, David; Cady, Eric; Exo-S Science; Technology Definition Team, Exoplanet Program Probe Study Design Team

    2015-01-01

    There is increasing interest in the use of a starshade, a spacecraft employing a large screen flying in formation with a space telescope, for providing the starlight suppression needed to detect and characterize exoplanets. In particular, Exo-S is a NASA study directed at designing a probe-scale exoplanet mission employing a starshade. In this poster we present the enabling technologies needed to make a starshade mission a reality: flight-like petals, a deployable truss to support the petals, optical edges, optical diffraction studies, and formation sensing and control. We show the status of each technology gap and summarize our progress over the past 5 years with plans for the next 3 years in demonstrating feasibility in all these areas. In particular, since no optical end-to-end test is possible, it is necessary to both show that a starshade can be built and deployed to the required accuracy and, via laboratory experiments at smaller scale, that the optical modeling upon which the accuracy requirements are based is validated. We show our progress verifying key enabling technologies, including demonstrating that a starshade petal made from flight-like materials can be manufactured to the needed accuracy and that a central truss with attached petals can be deployed with the needed precision. We also summarize our sub-scale lab experiments that demonstrate we can achieve the contrast predicted by our optical models.

  14. Modern trends in industrial technology of production of optical polymeric components for night vision devices

    NASA Astrophysics Data System (ADS)

    Goev, A. I.; Knyazeva, N. A.; Potelov, V. V.; Senik, B. N.

    2005-06-01

    The present paper represents in detail the complex approach to creating industrial technology of production of polymeric optical components: information has been given on optical polymeric materials, automatic machines for injection moulding, the possibilities of the Moldflow system (the AB "Universal" company) used for mathematical simulation of the technological process of injection moulding and making the moulds.

  15. Second-order schedules: discrimination of components1

    PubMed Central

    Squires, Nancy; Norborg, James; Fantino, Edmund

    1975-01-01

    Pigeons were exposed to a series of second-order schedules in which the completion of a fixed number of fixed-interval components produced food. In Experiment 1, brief (2 sec) stimulus presentations occurred as each fixed-interval component was completed. During the brief-stimulus presentation terminating the last fixed-interval component, a response was required on a second key, the brief-stimulus key, to produce food. Responses on the brief-stimulus key before the last brief-stimulus presentation had no scheduled consequences, but served as a measure of the extent to which the final component was discriminated from preceding components. Whether there were one, two, four, or eight fixed-interval components, responses on the brief-stimulus key occurred during virtually every brief-stimulus presentation. In Experiment 2, an attempt was made to punish unnecessary responses on the brief-stimulus key, i.e., responses on the brief-stimulus key that occurred before the last component. None of the pigeons learned to withhold these responses, even though they produced a 15-sec timeout and loss of primary reinforcement. In Experiment 3, different key colors were associated with each component of a second-order schedule (a chain schedule). In contrast to Experiment 1, brief-stimulus key responses were confined to the last component. It was concluded that pigeons do not discriminate well between components of second-order schedules unless a unique exteroceptive cue is provided for each component. The relative discriminability of the components may account for the observed differences in initial-component response rates between comparable brief-stimulus, tandem, and chain schedules. PMID:16811868

  16. Key technologies for expeditions to Mars.

    NASA Astrophysics Data System (ADS)

    French, J. R., Jr.

    A round-trip manned Mars landing mission, while difficult, is within the realm of today's technology. However, better understood and more practical advanced technologies offer promising improvements in mass performance, and some also enhance certain aspects of self-reliance for manned missions.

  17. Technology assessment in healthcare: a review and description of a "best practice" technology assessment process.

    PubMed

    Fernandez, A M; Schrogie, J J; Wilson, W W; Nash, D B

    1997-01-01

    Technology assessment has become a rapidly growing component of the healthcare system. It has assumed a functional role in operational settings and is rapidly impacting decisions involving purchasing, coverage, and reimbursement. This review is intended to assist the healthcare decision maker in considering the application of technology assessment in healthcare, so as to maximize the efficiency of future purchasing decisions. This "best practice" was synthesized after identifying key institutions performing technology assessment in healthcare and analyzing their working processes, including literature review, consensus panel discussions, and expert opinion. We describe this best practice on a reiterative loop that consists of five processes: awareness, strategic appropriateness, analysis versus need, acquisition and implementation, and reassessment. Typical barriers to adoption of technology assessment are also identified and discussed. This review suggests a common terminology for the core processes involved in technology assessment, thereby facilitating a more uniform understanding among the different components of the healthcare system (i.e., payer, provider, and society) while recognizing their different perspectives.

  18. Components of breeding productivity in a marine bird community: key factors and concordance

    USGS Publications Warehouse

    Hatch, Scott A.; Hatch, Martha A.

    1990-01-01

    We estimated components of annual breeding productivity for eight species of marine birds on the Semidi Islands in the western Gulf of Alaska. Mortality of eggs and young, caused primarily by avian predators, accounted for most of the annual variation in productivity. Failure to produce eggs, clutch size variation, and the hatchability of eggs were generally less important. The stage of breeding at which annual productivity was most strongly regulated differed among species. In murres, chick-rearing success accounted for the largest share of annual variation in overall productivity, whereas incubation success was the key factor in fulmars, kittiwakes, and puffins. Although avian predators were the dominant proximate cause of egg and chick losses in some species, food supply seemed ultimately responsible for variation in all the major components of productivity. Concordance of productivity among species was low for the marine bird community as a whole, but selected pairs of species exhibited a greater tendency for high and low productivities to occur in the same years. Compared with the same or similar species outside Alaska, Semidi Islands birds were in one of three categories: (i) species whose productivity was about the same as reported from other areas (fulmars and gulls), (ii) species with comparatively low productivity (murres, puffins, kittiwakes), and (iii) species with similar mean productivity but greater annual variation (cormorants). These patterns suggest that specialized consumers of forage fish experienced food shortages at the Semidi Islands and that surface feeders were more severely affected than divers.

  19. Research on key technology of prognostic and health management for autonomous underwater vehicle

    NASA Astrophysics Data System (ADS)

    Zhou, Zhi

    2017-12-01

    Autonomous Underwater Vehicles (AUVs) are non-cable and autonomous motional underwater robotics. With a wide range of activities, it can reach thousands of kilometers. Because it has the advantages of wide range, good maneuverability, safety and intellectualization, it becomes an important tool for various underwater tasks. How to improve diagnosis accuracy of the AUVs electrical system faults, and how to repair AUVs by the information are the focus of navy in the world. In turn, ensuring safe and reliable operation of the system has very important significance to improve AUVs sailing performance. To solve these problems, in the paper the prognostic and health management(PHM) technology is researched and used to AUV, and the overall framework and key technology are proposed, such as data acquisition, feature extraction, fault diagnosis, failure prediction and so on.

  20. Thin film technologies for optoelectronic components in fiber optic communication

    NASA Astrophysics Data System (ADS)

    Perinati, Agostino

    1998-02-01

    will grow at an annual average rate of 22 percent from 1.3 million fiber-km in 1995 to 3.5 million fiber-km in 2000. The worldwide components market-cable, transceivers and connectors - 6.1 billion in 1994, is forecasted to grow and show a 19 percent combined annual growth rate through the year 2000 when is predicted to reach 17.38 billion. Fiber-in-the-loop and widespread use of switched digital services will dominate this scenario being the fiber the best medium for transmitting multimedia services. As long as communication will partially replace transportation, multimedia services will push forward technology for systems and related components not only for higher performances but for lower cost too in order to get the consumers wanting to buy the new services. In the long distance transmission area (trunk network) higher integration of electronic and optoelectronic functions are required for transmitter and receiver in order to allow for higher system speed, moving from 2.5 Gb/s to 5, 10, 40 Gb/s; narrow band wavelength division multiplexing (WDM) filters are required for higher transmission capacity through multiwavelength technique and for optical amplifier. In the access area (distribution network) passive components as splitters, couplers, filters are needed together with optical amplifiers and transceivers for point-to-multipoint optical signal distribution: main issue in this area is the total cost to be paid by the customer for basic and new services. Multimedia services evolution, through fiber to the home and to the desktop approach, will be mainly affected by the availability of technologies suitable for component consistent integration, high yield manufacturing processes and final low cost. In this paper some of the optoelectronic components and related thin film technologies expected to mainly affect the fiber optic transmission evolution, either for long distance telecommunication systems or for subscriber network, are presented.

  1. Small Group Discussion as a Key Component in Online Assessment Training for Enhanced Student Learning in Web-Based Peer Assessment

    ERIC Educational Resources Information Center

    Liu, Xiongyi; Li, Lan; Zhang, Zhihong

    2018-01-01

    The purpose of this study is to examine the effect of online assessment training, with synchronous group discussion as a key component, on subsequent web-based peer assessment results. Participants included 81 college students, mostly women, taking a business writing class. After initial submission of a draft counter-offer letter, they completed…

  2. Research on the framework and key technologies of panoramic visualization for smart distribution network

    NASA Astrophysics Data System (ADS)

    Du, Jian; Sheng, Wanxing; Lin, Tao; Lv, Guangxian

    2018-05-01

    Nowadays, the smart distribution network has made tremendous progress, and the business visualization becomes even more significant and indispensable. Based on the summarization of traditional visualization technologies and demands of smart distribution network, a panoramic visualization application is proposed in this paper. The overall architecture, integrated architecture and service architecture of panoramic visualization application is firstly presented. Then, the architecture design and main functions of panoramic visualization system are elaborated in depth. In addition, the key technologies related to the application is discussed briefly. At last, two typical visualization scenarios in smart distribution network, which are risk warning and fault self-healing, proves that the panoramic visualization application is valuable for the operation and maintenance of the distribution network.

  3. Systems thinking for assistive technology: a commentary on the GREAT summit.

    PubMed

    MacLachlan, Malcolm; Scherer, Marcia J

    2018-07-01

    The area of assistive technology has a long history of technological ingenuity and innovation. In order to ensure that the benefits of assistive technology are equitably distributed across the population and life course, it is necessary to adopt a systemic approach to the area. We describe examples of systems thinking and non-systems thinking across 10 Ps. These Ps are People (or users, as the primary beneficiaries of assistive technology), Policy, Products, Personnel, Provision (as key strategic drivers at systems level); and Procurement, Place, Pace, Promotion and Partnership (as key situational factors for systems). Together these Ps should constitute a framework for an "open" system that can evolve and adapt, that empowers users, inter-connects key components and locates these in the reality of differing contexts. The adoption of a stronger systems thinking perspective within the assistive technology field should allow for more equitable, more resilient and more sustainable assistive technology across high, middle- and low-income contexts and countries. Implications for Rehabilitation The progress of assistive technology provison has been hampered by disconnected initiatives and activities and this needs to be corrected. Systems thinking is a way of thinking about the connections between things and how these are influenced by contextual and other factors. By encouraging the providers and users of assitive technology to think more systemically we can provide a more cohesive and resilient systems. The user experience is the central component of systems thinking in assistive technologies.

  4. New surface smoothing technologies for manufacturing of complex shaped glass components

    NASA Astrophysics Data System (ADS)

    Henkel, Sebastian; Schwager, Anne-Marie; Bliedtner, Jens; Götze, Kerstin; Rädlein, Edda; Schulze, Christian; Gerhardt, Martin; Fuhr, Michael

    2017-10-01

    The production of complex glass components with 2.5D or 3D-structures involves great effort and the need for advanced CNC-technology. Especially the final surface treatment, for generation of transparent surfaces, represents a timeconsuming and costly process. The ultrasonic-assisted grinding procedure is used to generate arbitrary shaped components and freeform-surfaces. The special kinematic principle, containing a high-frequency tool oscillation, enables efficient manufacturing processes. Surfaces produced in this way allow for application of novel smoothing methods, providing considerable advantages compared to classic polishing. It is shown, that manufacturing of transparent glass surfaces with low roughness down to Rq = 10 nm is possible, using an ultra-fine grinding process. By adding a CO2-laser polishing process, roughness can be reduced even further with a very short polishing time.

  5. Application of multi-tone mask technology in photolithographic fabrication of color filter components in LCD

    NASA Astrophysics Data System (ADS)

    Takada, Yoshihiro; Fukui, Matoko; Sai, Tsunehiro

    2008-11-01

    Recent progresses in the photoresists and photolithography for LCD industry applications have been primarily driven by the following two factors: advancement in the material performances (high resolution, high contrast ratio, low dielectric constant) for higher display quality, and cost reduction in the fabrication process. Along with crucial demand for cost competitiveness by improving production efficiency, environmental consciousness has been a major priority at fabrication process design to minimize the amount of waste produced. Having said the above, integration of two or more fabrication processes into a single process by using multi-tone mask technology has been the interest of research, due to its obvious advantage of reducing fabrication processes and cost. For example, multi-tone mask technology application has been widely employed on the TFT side to reduce the different types of photomasks being used. Similar trend has been employed on the CF side as well, where application of multi-tone mask technology is being investigated to integrate fabrication of multiple CF micro-components into a single process. In this presentation, we demonstrate a new approach of fabricating photospacer and peripheral CF components (MVA protrusion, sub-photospacers) in a single integrated process through multi-tone mask technology.

  6. Screening Active Components from Yu-Ping-Feng-San for Regulating Initiative Key Factors in Allergic Sensitization

    PubMed Central

    Zhu, Zhijie; Yu, Xi; Liu, Hailiang; Wang, Huizhu; Fan, Hongwei; Wang, Dawei; Jiang, Guorong; Hong, Min

    2014-01-01

    Yu-ping-feng-san (YPFS) is a Chinese medical formula that is used clinically for allergic diseases and characterized by reducing allergy relapse. Our previous studies demonstrated that YPFS efficiently inhibited T helper 2 cytokines in allergic inflammation. The underlying mechanisms of action of YPFS and its effective components remain unclear. In this study, it was shown that YPFS significantly inhibited production of thymic stromal lymphopoietin (TSLP), an epithelial cell-derived initiative factor in allergic inflammation, in vitro and in vivo. A method of human bronchial epithelial cell (16HBE) binding combined with HPLC-MS (named 16HBE-HPLC-MS) was established to explore potential active components of YPFS. The following five components bound to 16HBE cells: calycosin-7-glucoside, ononin, claycosin, sec-o-glucosylhamaudol and formononetin. Serum from YPFS-treated mice was analyzed and three major components were detected claycosin, formononetin and cimifugin. Among these, claycosin and formononetin were detected by 16HBE-HPLC-MS and in the serum of YPFS-treated mice. Claycosin and formononetin decreased the level of TSLP markedly at the initial stage of allergic inflammation in vivo. Nuclear factor (NF)-κB, a key transcription factor in TSLP production, was also inhibited by claycosin and formononetin, either in terms of transcriptional activation or its nuclear translocation in vitro. Allergic inflammation was reduced by claycosin and formononetin when they are administered only at the initial stage in a murine model of atopic contact dermatitis. Thus, epithelial cell binding combined with HPLC-MS is a valid method for screening active components from complex mixtures of Chinese medicine. It was demonstrated that the compounds screened from YPFS significantly attenuated allergic inflammation probably by reducing TSLP production via regulating NF-κB activation. PMID:25198676

  7. Paediatricians' opinions of microneedle-mediated monitoring: a key stage in the translation of microneedle technology from laboratory into clinical practice.

    PubMed

    Mooney, Karen; McElnay, James C; Donnelly, Ryan F

    2015-08-01

    Microneedle (MN) arrays could offer an alternative method to traditional drug delivery and blood sampling methods. However, acceptance among key end-users is critical for new technologies to succeed. MNs have been advocated for use in children and so, paediatricians are key potential end-users. However, the opinions of paediatricians on MN use have been previously unexplored. The aim of this study was to investigate the views of UK paediatricians on the use of MN technology within neonatal and paediatric care. An online survey was developed and distributed among UK paediatricians to gain their opinions of MN technology and its use in the neonatal and paediatric care settings, particularly for MN-mediated monitoring. A total of 145 responses were obtained, with a completion response rate of 13.7 %. Respondents believed an alternative monitoring technique to blood sampling in children was required. Furthermore, 83 % of paediatricians believed there was a particular need in premature neonates. Overall, this potential end-user group approved of the MN technology and a MN-mediated monitoring approach. Minimal pain and the perceived ease of use were important elements in gaining favour. Concerns included the need for confirmation of correct application and the potential for skin irritation. The findings of this study provide an initial indication of MN acceptability among a key potential end-user group. Furthermore, the concerns identified present a challenge to those working within the MN field to provide solutions to further improve this technology. The work strengthens the rationale behind MN technology and facilitates the translation of MN technology from lab bench into the clinical setting.

  8. Reducing the financial impact of pathogen inactivation technology for platelet components: our experience.

    PubMed

    Girona-Llobera, Enrique; Jimenez-Marco, Teresa; Galmes-Trueba, Ana; Muncunill, Josep; Serret, Carmen; Serra, Neus; Sedeño, Matilde

    2014-01-01

    Pathogen inactivation (PI) technology for blood components enhances blood safety by inactivating viruses, bacteria, parasites, and white blood cells. Additionally, PI for platelet (PLT) components has the potential to extend PLT storage time from 5 to 7 days. A retrospective analysis was conducted into the percentage of outdated PLT components during the 3 years before and after the adoption of PLT PI technology in our institution. The PLT transfusion dose for both pre-PI and post-PI periods was similar. A retrospective analysis to study clinical safety and component utilization was also performed in the Balearic Islands University Hospital. As a result of PI implementation in our institution, the PLT production cost increased by 85.5%. However, due to the extension of PLT storage time, the percentage of outdated PLT units substantially decreased (-83.9%) and, consequently, the cost associated with outdated units (-69.8%). This decrease represented a 13.7% reduction of the initial cost increase which, together with the saving in blood transportation (0.1%), led to a saving of 13.8% over the initial cost. Therefore, the initial 85.5% increase in the cost of PLT production was markedly reduced to 71.7%. The mean number of PLT concentrates per patient was similar during both periods. The extension of PLT storage time can substantially contribute to reducing the financial impact of PI by decreasing the percentage of outdated PLTs while improving blood safety. Since the adoption of PI, there have been no documented cases of PLT transfusion-related sepsis in our region. © 2013 American Association of Blood Banks.

  9. Screening of the key volatile organic compounds of Tuber melanosporum fermentation by aroma sensory evaluation combination with principle component analysis

    PubMed Central

    Liu, Rui-Sang; Jin, Guang-Huai; Xiao, Deng-Rong; Li, Hong-Mei; Bai, Feng-Wu; Tang, Ya-Jie

    2015-01-01

    Aroma results from the interplay of volatile organic compounds (VOCs) and the attributes of microbial-producing aromas are significantly affected by fermentation conditions. Among the VOCs, only a few of them contribute to aroma. Thus, screening and identification of the key VOCs is critical for microbial-producing aroma. The traditional method is based on gas chromatography-olfactometry (GC-O), which is time-consuming and laborious. Considering the Tuber melanosporum fermentation system as an example, a new method to screen and identify the key VOCs by combining the aroma evaluation method with principle component analysis (PCA) was developed in this work. First, an aroma sensory evaluation method was developed to screen 34 potential favorite aroma samples from 504 fermentation samples. Second, PCA was employed to screen nine common key VOCs from these 34 samples. Third, seven key VOCs were identified by the traditional method. Finally, all of the seven key VOCs identified by the traditional method were also identified, along with four others, by the new strategy. These results indicate the reliability of the new method and demonstrate it to be a viable alternative to the traditional method. PMID:26655663

  10. Simple Web-based interactive key development software (WEBiKEY) and an example key for Kuruna (Poaceae: Bambusoideae).

    PubMed

    Attigala, Lakshmi; De Silva, Nuwan I; Clark, Lynn G

    2016-04-01

    Programs that are user-friendly and freely available for developing Web-based interactive keys are scarce and most of the well-structured applications are relatively expensive. WEBiKEY was developed to enable researchers to easily develop their own Web-based interactive keys with fewer resources. A Web-based multiaccess identification tool (WEBiKEY) was developed that uses freely available Microsoft ASP.NET technologies and an SQL Server database for Windows-based hosting environments. WEBiKEY was tested for its usability with a sample data set, the temperate woody bamboo genus Kuruna (Poaceae). WEBiKEY is freely available to the public and can be used to develop Web-based interactive keys for any group of species. The interactive key we developed for Kuruna using WEBiKEY enables users to visually inspect characteristics of Kuruna and identify an unknown specimen as one of seven possible species in the genus.

  11. The Transformation of China's Key Science and Technology Universities in the Move to Mass Higher Education

    ERIC Educational Resources Information Center

    Zhou, Guangli; Zha, Qiang

    2010-01-01

    China's key science and technology universities are modelled on the French "Ecole Polytechnique". As such, they are utilitarian institutions, rooted in the concept of cultivating manpower for society's economic progress, and tending to ignore the development of the individual. As China's elite higher education system took in a rapidly…

  12. VfrB Is a Key Activator of the Staphylococcus aureus SaeRS Two-Component System.

    PubMed

    Krute, Christina N; Rice, Kelly C; Bose, Jeffrey L

    2017-03-01

    In previous studies, we identified the fatty acid kinase virulence factor regulator B (VfrB) as a potent regulator of α-hemolysin and other virulence factors in Staphylococcus aureus In this study, we demonstrated that VfrB is a positive activator of the SaeRS two-component regulatory system. Analysis of vfrB , saeR , and saeS mutant strains revealed that VfrB functions in the same pathway as SaeRS. At the transcriptional level, the promoter activities of SaeRS class I ( coa ) and class II ( hla ) target genes were downregulated during the exponential growth phase in the vfrB mutant, compared to the wild-type strain. In addition, saePQRS expression was decreased in the vfrB mutant strain, demonstrating a need for this protein in the autoregulation of SaeRS. The requirement for VfrB-mediated activation was circumvented when SaeS was constitutively active due to an SaeS (L18P) substitution. Furthermore, activation of SaeS via human neutrophil peptide 1 (HNP-1) overcame the dependence on VfrB for transcription from class I Sae promoters. Consistent with the role of VfrB in fatty acid metabolism, hla expression was decreased in the vfrB mutant with the addition of exogenous myristic acid. Lastly, we determined that aspartic acid residues D38 and D40, which are predicted to be key to VfrB enzymatic activity, were required for VfrB-mediated α-hemolysin production. Collectively, this study implicates VfrB as a novel accessory protein needed for the activation of SaeRS in S. aureus IMPORTANCE The SaeRS two-component system is a key regulator of virulence determinant production in Staphylococcus aureus Although the regulon of this two-component system is well characterized, the activation mechanisms, including the specific signaling molecules, remain elusive. Elucidating the complex regulatory circuit of SaeRS regulation is important for understanding how the system contributes to disease causation by this pathogen. To this end, we have identified the fatty acid kinase

  13. Novel EO/IR sensor technologies

    NASA Astrophysics Data System (ADS)

    Lewis, Keith

    2011-10-01

    The requirements for advanced EO/IR sensor technologies are discussed in the context of evolving military operations, with significant emphasis on the development of new sensing technologies to meet the challenges posed by asymmetric threats. The Electro-Magnetic Remote Sensing (EMRS DTC) was established in 2003 to provide a centre of excellence in sensor research and development, supporting new capabilities in key military areas such as precision attack, battlespace manoeuvre and information superiority. In the area of advanced electro-optic technology, the DTC has supported work on discriminative imaging, advanced detectors, laser components/technologies, and novel optical techniques. This paper provides a summary of some of the EO/IR technologies explored by the DTC.

  14. The application design of a mobile terminal: key technologies of mobile location-based service system

    NASA Astrophysics Data System (ADS)

    Tong, Xiaohui; Liu, Jingao; Wang, Zhenghao; Wang, Shuxian

    2004-03-01

    This paper presents several key technologies in the Mobile Location Based Service (MLBS) system of Shanghai. In the paper, the author presents a solution of handset mobile terminal, PDA+GPS+GSM/GPRS. The paper particularly introduces the hardware of the terminal and the acquirement of GPS information at the terminal. The paper also introduces how the terminal communicates with the special service center.

  15. The study on the near infrared spectrum technology of sauce component analysis

    NASA Astrophysics Data System (ADS)

    Li, Shangyu; Zhang, Jun; Chen, Xingdan; Liang, Jingqiu; Wang, Ce

    2006-01-01

    The author, Shangyu Li, engages in supervising and inspecting the quality of products. In soy sauce manufacturing, quality control of intermediate and final products by many components such as total nitrogen, saltless soluble solids, nitrogen of amino acids and total acid is demanded. Wet chemistry analytical methods need much labor and time for these analyses. In order to compensate for this problem, we used near infrared spectroscopy technology to measure the chemical-composition of soy sauce. In the course of the work, a certain amount of soy sauce was collected and was analyzed by wet chemistry analytical methods. The soy sauce was scanned by two kinds of the spectrometer, the Fourier Transform near infrared spectrometer (FT-NIR spectrometer) and the filter near infrared spectroscopy analyzer. The near infrared spectroscopy of soy sauce was calibrated with the components of wet chemistry methods by partial least squares regression and stepwise multiple linear regression. The contents of saltless soluble solids, total nitrogen, total acid and nitrogen of amino acids were predicted by cross validation. The results are compared with the wet chemistry analytical methods. The correlation coefficient and root-mean-square error of prediction (RMSEP) in the better prediction run were found to be 0.961 and 0.206 for total nitrogen, 0.913 and 1.215 for saltless soluble solids, 0.855 and 0.199 nitrogen of amino acids, 0.966 and 0.231 for total acid, respectively. The results presented here demonstrate that the NIR spectroscopy technology is promising for fast and reliable determination of major components of soy sauce.

  16. Small Engine Component Technology (SECT) study

    NASA Technical Reports Server (NTRS)

    Larkin, T. R.

    1986-01-01

    The objective of this study is to identify high payoff technologies for year 2000 small gas turbine engines, and to provide a technology plan to guide research and technology efforts toward revolutionizing the small gas turbine technology base. The goal is to define the required technology to provide a 30 percent reduction in mission fuel burned, to reduce direct operating costs by at least 10 percent, and to provide increased reliability and durability of the gas turbine propulsion system. The baseline established to evaluate the year 2000 technology base was an 8-passenger commercial tilt-rotor aircraft powered by a current technology gas turbine engine. Three basic engine cycles were studied: the simple cycle engine, a waste heat recovery cycle, and a wave rotor engine cycle. For the simple cycle engine, two general arrangements were considered: the traditional concentric spool arrangement and a nonconcentric spool arrangement. Both a regenerative and a recuperative cycle were studied for the waste heat recovery cycle.

  17. Key Performance Parameter Driven Technology Goals for Electric Machines and Power Systems

    NASA Technical Reports Server (NTRS)

    Bowman, Cheryl; Jansen, Ralph; Brown, Gerald; Duffy, Kirsten; Trudell, Jeffrey

    2015-01-01

    Transitioning aviation to low carbon propulsion is one of the crucial strategic research thrust and is a driver in the search for alternative propulsion system for advanced aircraft configurations. This work requires multidisciplinary skills coming from multiple entities. The feasibility of scaling up various electric drive system technologies to meet the requirements of a large commercial transport is discussed in terms of key parameters. Functional requirements are identified that impact the power system design. A breakeven analysis is presented to find the minimum allowable electric drive specific power and efficiency that can preserve the range, initial weight, operating empty weight, and payload weight of the base aircraft.

  18. Growing-up just like everyone else: key components of a successful pediatric HIV disclosure intervention in Namibia

    PubMed Central

    Brandt, Laura; Beima-Sofie, Kristin; Hamunime, Ndapewa; Shepard, Mark; Ferris, Larissa; Ingo, Paulina; John-Stewart, Grace; O’Malley, Gabrielle

    2018-01-01

    Objectives To facilitate replication and adaptation of pediatric HIV disclosure interventions, we identified key components of a child-friendly cartoon book used to guide Namibian caregivers and healthcare workers (HCWs) through a gradual, structured disclosure process. Design Qualitative interviews were conducted with caregivers and HCWs from four high-volume pediatric HIV clinics in Namibia. Methods Semi-structured in-depth interviews with 35 HCWs and 64 caregivers of HIV+ children aged 7–15 were analyzed using constant comparative and modified grounded theory analysis. Major barriers to disclosure were compared to accounts of intervention success, and themes related to key components were identified. Results The disclosure book overcomes barriers to disclosure by reducing caregiver resistance, increasing HIV and disclosure knowledge, and providing a gradual, structured framework for disclosure. The delayed mention of HIV-specific terminology overcomes caregiver fears associated with HIV stigma, thus encouraging earlier uptake of disclosure initiation. Caregivers value the book’s focus on staying healthy, keeping the body strong, and having a future ‘like other kids’, thus capitalizing on evidence of the positive benefits of resilience and hopefulness rather than the negative consequences of HIV. The book’s concepts and images resonate with children who readily adopt the language of ‘body soldiers’ and ‘bad guys’ in describing how important it is for them to take their medicine. Discussion cues ease communication between HCWs, caregivers, and pediatric patients. Conclusion Given the urgent need for available pediatric HIV disclosure interventions, easily implementable tools like the Namibian disclosure book should be evaluated for utility in similar settings. PMID:26049542

  19. Growing-up just like everyone else: key components of a successful pediatric HIV disclosure intervention in Namibia.

    PubMed

    Brandt, Laura; Beima-Sofie, Kristin; Hamunime, Ndapewa; Shepard, Mark; Ferris, Larissa; Ingo, Paulina; John-Stewart, Grace; O'Malley, Gabrielle

    2015-06-01

    To facilitate replication and adaptation of pediatric HIV disclosure interventions, we identified key components of a child-friendly cartoon book used to guide Namibian caregivers and healthcare workers (HCWs) through a gradual, structured disclosure process. Qualitative interviews were conducted with caregivers and HCWs from four high-volume pediatric HIV clinics in Namibia. Semi-structured in-depth interviews with 35 HCWs and 64 caregivers of HIV+ children aged 7-15 were analyzed using constant comparative and modified grounded theory analysis. Major barriers to disclosure were compared to accounts of intervention success, and themes related to key components were identified. The disclosure book overcomes barriers to disclosure by reducing caregiver resistance, increasing HIV and disclosure knowledge, and providing a gradual, structured framework for disclosure. The delayed mention of HIV-specific terminology overcomes caregiver fears associated with HIV stigma, thus encouraging earlier uptake of disclosure initiation. Caregivers value the book's focus on staying healthy, keeping the body strong, and having a future 'like other kids', thus capitalizing on evidence of the positive benefits of resilience and hopefulness rather than the negative consequences of HIV. The book's concepts and images resonate with children who readily adopt the language of 'body soldiers' and 'bad guys' in describing how important it is for them to take their medicine. Discussion cues ease communication between HCWs, caregivers, and pediatric patients. Given the urgent need for available pediatric HIV disclosure interventions, easily implementable tools like the Namibian disclosure book should be evaluated for utility in similar settings.

  20. Technology transfer: the key to fusion commercialization

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Burnett, S.C.

    1981-01-01

    The paper brings to light some of the reasons why technology transfer is difficult in fusion, examines some of the impediments to the process, and finally looks at a successful example of technology transfer. The paper considers some subjective features of fusion - one might call them the sociology of fusion - that are none the less real and that serve as impediments to technology transfer.

  1. Just-in-Time Adaptive Interventions (JITAIs) in Mobile Health: Key Components and Design Principles for Ongoing Health Behavior Support.

    PubMed

    Nahum-Shani, Inbal; Smith, Shawna N; Spring, Bonnie J; Collins, Linda M; Witkiewitz, Katie; Tewari, Ambuj; Murphy, Susan A

    2018-05-18

    The just-in-time adaptive intervention (JITAI) is an intervention design aiming to provide the right type/amount of support, at the right time, by adapting to an individual's changing internal and contextual state. The availability of increasingly powerful mobile and sensing technologies underpins the use of JITAIs to support health behavior, as in such a setting an individual's state can change rapidly, unexpectedly, and in his/her natural environment. Despite the increasing use and appeal of JITAIs, a major gap exists between the growing technological capabilities for delivering JITAIs and research on the development and evaluation of these interventions. Many JITAIs have been developed with minimal use of empirical evidence, theory, or accepted treatment guidelines. Here, we take an essential first step towards bridging this gap. Building on health behavior theories and the extant literature on JITAIs, we clarify the scientific motivation for JITAIs, define their fundamental components, and highlight design principles related to these components. Examples of JITAIs from various domains of health behavior research are used for illustration. As we enter a new era of technological capacity for delivering JITAIs, it is critical that researchers develop sophisticated and nuanced health behavior theories capable of guiding the construction of such interventions. Particular attention has to be given to better understanding the implications of providing timely and ecologically sound support for intervention adherence and retention.

  2. A comparison of forming technologies for ceramic gas-turbine engine components

    NASA Technical Reports Server (NTRS)

    Hengst, R. R.; Heichel, D. N.; Holowczak, J. E.; Taglialavore, A. P.; Mcentire, B. J.

    1990-01-01

    For over ten years, injection molding and slip casting have been actively developed as forming techniques for ceramic gas turbine components. Co-development of these two processes has continued within the U.S. DOE-sponsored Advanced Turbine Technology Application Project (ATTAP). Progress within ATTAP with respect to these two techniques is summarized. A critique and comparison of the two processes are given. Critical aspects of both processes with respect to size, dimensional control, material properties, quality, cost, and potential for manufacturing scale-up are discussed.

  3. Composite armored vehicle advanced technology demonstator

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ostberg, D.T.; Dunfee, R.S.; Thomas, G.E.

    1996-12-31

    Composite structures are a key technology needed to develop future lightweight combat vehicles that are both deployable and survivable. The Composite Armored Vehicle Advanced Technology Demonstrator Program that started in fiscal year 1994 will continue through 1998 to verily that composite structures are a viable solution for ground combat vehicles. Testing thus far includes material characterization, structural component tests and full scale quarter section tests. Material and manufacturing considerations, tests, results and changes, and the status of the program will be described. The structural component tests have been completed successfully, and quarter section testing is in progress. Upon completion ofmore » the critical design review, the vehicle demonstrator will be Fabricated and undergo government testing.« less

  4. Are Key Principles for improved health technology assessment supported and used by health technology assessment organizations?

    PubMed

    Neumann, Peter J; Drummond, Michael F; Jönsson, Bengt; Luce, Bryan R; Schwartz, J Sanford; Siebert, Uwe; Sullivan, Sean D

    2010-01-01

    Previously, our group-the International Working Group for HTA Advancement-proposed a set of fifteen Key Principles that could be applied to health technology assessment (HTA) programs in different jurisdictions and across a range of organizations and perspectives. In this commentary, we investigate the extent to which these principles are supported and used by fourteen selected HTA organizations worldwide. We find that some principles are broadly supported: examples include being explicit about HTA goals and scope; considering a wide range of evidence and outcomes; and being unbiased and transparent. Other principles receive less widespread support: examples are addressing issues of generalizability and transferability; being transparent on the link between HTA findings and decision-making processes; considering a full societal perspective; and monitoring the implementation of HTA findings. The analysis also suggests a lack of consensus in the field about some principles--for example, considering a societal perspective. Our study highlights differences in the uptake of key principles for HTA and indicates considerable room for improvement for HTA organizations to adopt principles identified to reflect good HTA practices. Most HTA organizations espouse certain general concepts of good practice--for example, assessments should be unbiased and transparent. However, principles that require more intensive follow-up--for example, monitoring the implementation of HTA findings--have received little support and execution.

  5. Small Engine Component Technology (SECT) study

    NASA Technical Reports Server (NTRS)

    Singh, B.

    1986-01-01

    Small advanced (450 to 850 pounds thrust, 2002 to 3781 N) gas turbine engines were studied for a subsonic strategic cruise missile application, using projected year 2000 technology. An aircraft, mission characteristics, and baseline (state-of-the-art) engine were defined to evaluate technology benefits. Engine performance and configuration analyses were performed for two and three spool turbofan and propfan engine concepts. Mission and Life Cycle Cost (LCC) analyses were performed in which the candidate engines were compared to the baseline engines over a prescribed mission. The advanced technology engines reduced system LCC up to 41 percent relative to the baseline engine. Critical aerodynamic, materials, and mechanical systems turbine engine technologies were identified and program plans were defined for each identified critical technology.

  6. Simple Web-based interactive key development software (WEBiKEY) and an example key for Kuruna (Poaceae: Bambusoideae)1

    PubMed Central

    Attigala, Lakshmi; De Silva, Nuwan I.; Clark, Lynn G.

    2016-01-01

    Premise of the study: Programs that are user-friendly and freely available for developing Web-based interactive keys are scarce and most of the well-structured applications are relatively expensive. WEBiKEY was developed to enable researchers to easily develop their own Web-based interactive keys with fewer resources. Methods and Results: A Web-based multiaccess identification tool (WEBiKEY) was developed that uses freely available Microsoft ASP.NET technologies and an SQL Server database for Windows-based hosting environments. WEBiKEY was tested for its usability with a sample data set, the temperate woody bamboo genus Kuruna (Poaceae). Conclusions: WEBiKEY is freely available to the public and can be used to develop Web-based interactive keys for any group of species. The interactive key we developed for Kuruna using WEBiKEY enables users to visually inspect characteristics of Kuruna and identify an unknown specimen as one of seven possible species in the genus. PMID:27144109

  7. Electrical Components for Marine Renewable Energy Arrays: A Techno-Economic Review

    DOE PAGES

    Collin, Adam J.; Nambiar, Anup J.; Bould, David; ...

    2017-11-27

    This paper presents a review of the main electrical components that are expected to be present in marine renewable energy arrays. The review is put in context by appraising the current needs of the industry and identifying the key components required in both device and array-scale developments. For each component, electrical, mechanical and cost considerations are discussed; with quantitative data collected during the review made freely available for use by the community via an open access online repository. Here, this data collection updates previous research and addresses gaps specific to emerging offshore technologies, such as marine and floating wind, andmore » provides a comprehensive resource for the techno-economic assessment of offshore energy arrays.« less

  8. Electrical Components for Marine Renewable Energy Arrays: A Techno-Economic Review

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Collin, Adam J.; Nambiar, Anup J.; Bould, David

    This paper presents a review of the main electrical components that are expected to be present in marine renewable energy arrays. The review is put in context by appraising the current needs of the industry and identifying the key components required in both device and array-scale developments. For each component, electrical, mechanical and cost considerations are discussed; with quantitative data collected during the review made freely available for use by the community via an open access online repository. Here, this data collection updates previous research and addresses gaps specific to emerging offshore technologies, such as marine and floating wind, andmore » provides a comprehensive resource for the techno-economic assessment of offshore energy arrays.« less

  9. Depletion of key protein components of the RISC pathway impairs pre-ribosomal RNA processing.

    PubMed

    Liang, Xue-Hai; Crooke, Stanley T

    2011-06-01

    Little is known about whether components of the RNA-induced silencing complex (RISC) mediate the biogenesis of RNAs other than miRNA. Here, we show that depletion of key proteins of the RISC pathway by antisense oligonucleotides significantly impairs pre-rRNA processing in human cells. In cells depleted of Drosha or Dicer, different precursors to 5.8S rRNA strongly accumulated, without affecting normal endonucleolytic cleavages. Moderate yet distinct processing defects were also observed in Ago2-depleted cells. Physical links between pre-rRNA and these proteins were identified by co-immunoprecipitation analyses. Interestingly, simultaneous depletion of Dicer and Drosha led to a different processing defect, causing slower production of 28S rRNA and its precursor. Both Dicer and Ago2 were detected in the nuclear fraction, and reduction of Dicer altered the structure of the nucleolus, where pre-rRNA processing occurs. Together, these results suggest that Drosha and Dicer are implicated in rRNA biogenesis.

  10. Just-in-Time Adaptive Interventions (JITAIs) in Mobile Health: Key Components and Design Principles for Ongoing Health Behavior Support

    PubMed Central

    Nahum-Shani, Inbal; Smith, Shawna N.; Spring, Bonnie J.; Collins, Linda M.; Witkiewitz, Katie; Tewari, Ambuj; Murphy, Susan A.

    2016-01-01

    Background The just-in-time adaptive intervention (JITAI) is an intervention design aiming to provide the right type/amount of support, at the right time, by adapting to an individual's changing internal and contextual state. The availability of increasingly powerful mobile and sensing technologies underpins the use of JITAIs to support health behavior, as in such a setting an individual's state can change rapidly, unexpectedly, and in his/her natural environment. Purpose Despite the increasing use and appeal of JITAIs, a major gap exists between the growing technological capabilities for delivering JITAIs and research on the development and evaluation of these interventions. Many JITAIs have been developed with minimal use of empirical evidence, theory, or accepted treatment guidelines. Here, we take an essential first step towards bridging this gap. Methods Building on health behavior theories and the extant literature on JITAIs, we clarify the scientific motivation for JITAIs, define their fundamental components, and highlight design principles related to these components. Examples of JITAIs from various domains of health behavior research are used for illustration. Conclusion As we enter a new era of technological capacity for delivering JITAIs, it is critical that researchers develop sophisticated and nuanced health behavior theories capable of guiding the construction of such interventions. Particular attention has to be given to better understanding the implications of providing timely and ecologically sound support for intervention adherence and retention. PMID:27663578

  11. 10. Freiburger Symposium 2011 der SCG-Division Industrielle Chemie Technology Progress, Success Key for our Production Sites.

    PubMed

    Naef, Olivier

    2012-01-01

    This short paper presents the abstracts of the different presentations during 10. Freiburger Symposium 2011 der SCG-Division Industrielle Chemie: Technology Progress, Success key for our production sites held Thursday and Friday, September 29 and 30, 2011 at the Ecole d'ingénieurs et d'architectes de Fribourg (Switzerland).

  12. Fabrication of a resin appliance with alloy components using digital technology without an analog impression.

    PubMed

    Al Mortadi, Noor; Jones, Quentin; Eggbeer, Dominic; Lewis, Jeffrey; Williams, Robert J

    2015-11-01

    The aim of this study was to fabricate a resin appliance incorporating "wire" components without the use of an analog impression and dental casts using an intraoral scanner and computer technology to build the appliance. This unique alignment of technology offers an enormous reduction in the number of fabrication steps when compared with more traditional methods of manufacture. The prototype incorporated 2 Adams clasps and a fitted labial bow. The alloy components were built from cobalt-chromium in an initial powdered form using established digital technology methods and then inserted into a build of a resin base plate. This article reports the first known use of computer-aided design and additive manufacture to fabricate a resin and alloy appliance, and constitutes proof of the concept for such manufacturing. The original workflow described could be seen as an example for many other similar appliances, perhaps with active components. The scan data were imported into an appropriate specialized computer-aided design software, which was used in conjunction with a force feedback (haptic) interface. The appliance designs were then exported as stereolithography files and transferred to an additive manufacturing machine for fabrication. The results showed that the applied techniques may provide new manufacturing and design opportunities in orthodontics and highlights the need for intraoral-specific additive manufacture materials to be produced and tested for biocompatibility compliance. In a trial, the retainer was fitted orally and judged acceptable by the clinician according to the typical criteria when placing such appliances in situ. Copyright © 2015 American Association of Orthodontists. Published by Elsevier Inc. All rights reserved.

  13. Bonding and Integration Technologies for Silicon Carbide Based Injector Components

    NASA Technical Reports Server (NTRS)

    Halbig, Michael C.; Singh, Mrityunjay

    2008-01-01

    Advanced ceramic bonding and integration technologies play a critical role in the fabrication and application of silicon carbide based components for a number of aerospace and ground based applications. One such application is a lean direct injector for a turbine engine to achieve low NOx emissions. Ceramic to ceramic diffusion bonding and ceramic to metal brazing technologies are being developed for this injector application. For the diffusion bonding, titanium interlayers (PVD and foils) were used to aid in the joining of silicon carbide (SiC) substrates. The influence of such variables as surface finish, interlayer thickness (10, 20, and 50 microns), processing time and temperature, and cooling rates were investigated. Microprobe analysis was used to identify the phases in the bonded region. For bonds that were not fully reacted an intermediate phase, Ti5Si3Cx, formed that is thermally incompatible in its thermal expansion and caused thermal stresses and cracking during the processing cool-down. Thinner titanium interlayers and/or longer processing times resulted in stable and compatible phases that did not contribute to microcracking and resulted in an optimized microstructure. Tensile tests on the joined materials resulted in strengths of 13-28 MPa depending on the SiC substrate material. Non-destructive evaluation using ultrasonic immersion showed well formed bonds. For the joining technology of brazing Kovar fuel tubes to silicon carbide, preliminary development of the joining approach has begun. Various technical issues and requirements for the injector application are addressed.

  14. Technology-Based Lesson Plans: Preparation and Description

    ERIC Educational Resources Information Center

    Kubilinskiene, Svetlana; Dagiene, Valentina

    2010-01-01

    A lesson plan is an important methodological component of the learning process. The key purpose of the article is to analyse the current situation and suggest how the information technologies can assist in the development of lesson plans, their accumulation and retrieval, thus ensuring their effective application. The authors disclose the problems…

  15. MEMS Deformable Mirror Technology Development for Space-Based Exoplanet Detection

    NASA Astrophysics Data System (ADS)

    Bierden, Paul; Cornelissen, S.; Ryan, P.

    2014-01-01

    In the search for earth-like extrasolar planets that has become an important objective for NASA, a critical technology development requirement is to advance deformable mirror (DM) technology. High-actuator-count DMs are critical components for nearly all proposed coronagraph instrument concepts. The science case for exoplanet imaging is strong, and rapid recent advances in test beds with DMs made using microelectromechanical system (MEMS) technology have motivated a number of compelling mission concepts that set technical specifications for their use as wavefront controllers. This research will advance the technology readiness of the MEMS DMs components that are currently at the forefront of the field, and the project will be led by the manufacturer of those components, Boston Micromachines Corporation (BMC). The project aims to demonstrate basic functionality and performance of this key component in critical test environments and in simulated operational environments, while establishing model-based predictions of its performance relative to launch and space environments. Presented will be the current status of the project with modeling and initial test results.

  16. Key Considerations of Community, Scalability, Supportability, Security, and Functionality in Selecting Open-Source Software in California Universities as Perceived by Technology Leaders

    ERIC Educational Resources Information Center

    Britton, Todd Alan

    2014-01-01

    Purpose: The purpose of this study was to examine the key considerations of community, scalability, supportability, security, and functionality for selecting open-source software in California universities as perceived by technology leaders. Methods: After a review of the cogent literature, the key conceptual framework categories were identified…

  17. Phosphoinositide 3-kinase (PI3K(p110alpha)) directly regulates key components of the Z-disc and cardiac structure.

    PubMed

    Waardenberg, Ashley J; Bernardo, Bianca C; Ng, Dominic C H; Shepherd, Peter R; Cemerlang, Nelly; Sbroggiò, Mauro; Wells, Christine A; Dalrymple, Brian P; Brancaccio, Mara; Lin, Ruby C Y; McMullen, Julie R

    2011-09-02

    Maintenance of cardiac structure and Z-disc signaling are key factors responsible for protecting the heart in a setting of stress, but how these processes are regulated is not well defined. We recently demonstrated that PI3K(p110α) protects the heart against myocardial infarction. The aim of this study was to determine whether PI3K(p110α) directly regulates components of the Z-disc and cardiac structure. To address this question, a unique three-dimensional virtual muscle model was applied to gene expression data from transgenic mice with increased or decreased PI3K(p110α) activity under basal conditions (sham) and in a setting of myocardial infarction to display the location of structural proteins. Key findings from this analysis were then validated experimentally. The three-dimensional virtual muscle model visually highlighted reciprocally regulated transcripts associated with PI3K activation that encoded key components of the Z-disc and costamere, including melusin. Studies were performed to assess whether PI3K and melusin interact in the heart. Here, we identify a novel melusin-PI3K interaction that generates lipid kinase activity. The direct impact of PI3K(p110α) on myocyte structure was assessed by treating neonatal rat ventricular myocytes with PI3K(p110α) inhibitors and examining the myofiber morphology of hearts from PI3K transgenic mice. Results demonstrate that PI3K is critical for myofiber maturation and Z-disc alignment. In summary, PI3K regulates the expression of genes essential for cardiac structure and Z-disc signaling, interacts with melusin, and is critical for Z-disc alignment.

  18. Phosphoinositide 3-Kinase (PI3K(p110α)) Directly Regulates Key Components of the Z-disc and Cardiac Structure*

    PubMed Central

    Waardenberg, Ashley J.; Bernardo, Bianca C.; Ng, Dominic C. H.; Shepherd, Peter R.; Cemerlang, Nelly; Sbroggiò, Mauro; Wells, Christine A.; Dalrymple, Brian P.; Brancaccio, Mara; Lin, Ruby C. Y.; McMullen, Julie R.

    2011-01-01

    Maintenance of cardiac structure and Z-disc signaling are key factors responsible for protecting the heart in a setting of stress, but how these processes are regulated is not well defined. We recently demonstrated that PI3K(p110α) protects the heart against myocardial infarction. The aim of this study was to determine whether PI3K(p110α) directly regulates components of the Z-disc and cardiac structure. To address this question, a unique three-dimensional virtual muscle model was applied to gene expression data from transgenic mice with increased or decreased PI3K(p110α) activity under basal conditions (sham) and in a setting of myocardial infarction to display the location of structural proteins. Key findings from this analysis were then validated experimentally. The three-dimensional virtual muscle model visually highlighted reciprocally regulated transcripts associated with PI3K activation that encoded key components of the Z-disc and costamere, including melusin. Studies were performed to assess whether PI3K and melusin interact in the heart. Here, we identify a novel melusin-PI3K interaction that generates lipid kinase activity. The direct impact of PI3K(p110α) on myocyte structure was assessed by treating neonatal rat ventricular myocytes with PI3K(p110α) inhibitors and examining the myofiber morphology of hearts from PI3K transgenic mice. Results demonstrate that PI3K is critical for myofiber maturation and Z-disc alignment. In summary, PI3K regulates the expression of genes essential for cardiac structure and Z-disc signaling, interacts with melusin, and is critical for Z-disc alignment. PMID:21757757

  19. Exploring safety systems for dispensing in community pharmacies: focusing on how staff relate to organizational components.

    PubMed

    Harvey, Jasmine; Avery, Anthony J; Ashcroft, Darren; Boyd, Matthew; Phipps, Denham L; Barber, Nicholas

    2015-01-01

    Identifying risk is an important facet of a safety practice in an organization. To identify risk, all components within a system of operation should be considered. In clinical safety practice, a team of people, technologies, procedures and protocols, management structure and environment have been identified as key components in a system of operation. To explore risks in relation to prescription dispensing in community pharmacies by taking into account relationships between key components that relate to the dispensing process. Fifteen community pharmacies in England with varied characteristics were identified, and data were collected using non-participant observations, shadowing and interviews. Approximately 360 hours of observations and 38 interviews were conducted by the team. Observation field notes from each pharmacy were written into case studies. Overall, 52,500 words from 15 case studies and interview transcripts were analyzed using thematic and line-by-line analyses. Validation techniques included multiple data collectors co-authoring each case study for consensus, review of case studies by members of the wider team including academic and practicing community pharmacists, and patient safety experts and two presentations (internally and externally) to review and discuss findings. Risks identified were related to relationships between people and other key components in dispensing. This included how different levels of staff communicated internally and externally, followed procedures, interacted with technical systems, worked with management, and engaged with the environment. In a dispensing journey, the following categories were identified which show how risks are inextricably linked through relationships between human components and other key components: 1) dispensing with divided attention; 2) dispensing under pressure; 3) dispensing in a restricted space or environment; and, 4) managing external influences. To identify and evaluate risks effectively, an

  20. MOEMs, key optical components for future astronomical instrumentation in space

    NASA Astrophysics Data System (ADS)

    Zamkotsian, Frédéric; Dohlen, Kjetil; Burgarella, Denis; Ferrari, Marc; Buat, Veronique

    2017-11-01

    Based on the micro-electronics fabrication process, MicroOpto-Electro-Mechanical Systems (MOEMS) are under study, in order to be integrated in next-generation astronomical instruments and telescopes, especially for space missions. The main advantages of micro-optical components are their compactness, scalability, specific task customization using elementary building blocks, and they allows remote control. As these systems are easily replicable, the price of the components is decreasing dramatically when their number is increasing. The two major applications of MOEMS are Multi-Object Spectroscopy masks and Deformable Mirror systems.

  1. The component alignment model: a new approach to health care information technology strategic planning.

    PubMed

    Martin, J B; Wilkins, A S; Stawski, S K

    1998-08-01

    The evolving health care environment demands that health care organizations fully utilize information technologies (ITs). The effective deployment of IT requires the development and implementation of a comprehensive IT strategic plan. A number of approaches to health care IT strategic planning exist, but they are outdated or incomplete. The component alignment model (CAM) introduced here recognizes the complexity of today's health care environment, emphasizing continuous assessment and realignment of seven basic components: external environment, emerging ITs, organizational infrastructure, mission, IT infrastructure, business strategy, and IT strategy. The article provides a framework by which health care organizations can develop an effective IT strategic planning process.

  2. Argo workstation: a key component of operational oceanography

    NASA Astrophysics Data System (ADS)

    Dong, Mingmei; Xu, Shanshan; Miao, Qingsheng; Yue, Xinyang; Lu, Jiawei; Yang, Yang

    2018-02-01

    Operational oceanography requires the quantity, quality, and availability of data set and the timeliness and effectiveness of data products. Without steady and strong operational system supporting, operational oceanography will never be proceeded far. In this paper we describe an integrated platform named Argo Workstation. It operates as a data processing and management system, capable of data collection, automatic data quality control, visualized data check, statistical data search and data service. After it is set up, Argo workstation provides global high quality Argo data to users every day timely and effectively. It has not only played a key role in operational oceanography but also set up an example for operational system.

  3. Composite Sandwich Technologies Lighten Components

    NASA Technical Reports Server (NTRS)

    2010-01-01

    Leveraging its private resources with several Small Business Innovation Research (SBIR) contracts with both NASA and the U.S. Department of Defense, WebCore Technologies LLC, of Miamisburg, Ohio, developed a fiber-reinforced foam sandwich panel it calls TYCOR that can be used for a wide variety of industrial and consumer applications. Testing at Glenn Research Center?s Ballistic Impact Facility demonstrated that the technology was able to exhibit excellent damage localization and stiffness during impact. The patented and trademarked material has found use in many demanding applications, including marine, ground transportation, mobile shelters, bridges, and most notably, wind turbines.

  4. Revealing Optical Components

    NASA Technical Reports Server (NTRS)

    2002-01-01

    The Optical Vector Analyzer (OVA) 1550 significantly reduces the time and cost of testing sophisticated optical components. The technology grew from the research Luna Technologies' Dr. Mark Froggatt conducted on optical fiber strain measurement while working at Langley Research Center. Dr. Froggatt originally developed the technology for non- destructive evaluation testing at Langley. The new technique can provide 10,000 independent strain measurements while adding less than 10 grams to the weight of the vehicle. The OVA is capable of complete linear characterization of single-mode optical components used in high- bit-rate applications. The device can test most components over their full range in less than 30 seconds, compared to the more than 20 minutes required by other testing methods. The dramatically shortened measurement time results in increased efficiency in final acceptance tests of optical devices, and the comprehensive data produced by the instrument adds considerable value for component consumers. The device eliminates manufacturing bottlenecks, while reducing labor costs and wasted materials during production.

  5. The key quality control technology of main cable erection in long-span suspension bridge construction

    NASA Astrophysics Data System (ADS)

    Chen, Yongrui; Wei, Wei; Dai, Jie

    2017-04-01

    Main cable is one of the most important structure of suspension Bridges, which bear all the dead and live load from upper structure. Cable erection is one of the most critical process in suspension bridge construction. Key points about strand erection are studied in this paper, including strand traction, lateral movement, section adjustment, placing into saddle, anchoring, line shape adjustment and keeping, and tension control. The technology has helped a long-span suspension bridge in Yunnan Province, China get a ideal finished state.

  6. Key-peck durations under behavioral contrast and differential reinforcement

    PubMed Central

    Whipple, William R.; Fantino, Edmund

    1980-01-01

    Pigeons were maintained on a multiple schedule in which both components were variable-interval one-minute schedules. When they were switched to a condition in which one component was extinction, behavioral contrast was observed. The median durations of the key pecks in the unchanged component did not decrease in size. The results are incompatible with a theory of behavioral contrast which considers the added pecks to be short-duration responses. In a second experiment, pigeons were required to emit short-duration key pecks in one component of a multiple schedule, and long-duration pecks in the other. Two of three pigeons learned to emit responses appropriate to the requirements of the component in effect, suggesting that the duration of the key-peck response is sensitive to differential reinforcement. PMID:16812185

  7. The use of smart technologies in enabling construction components reuse: A viable method or a problem creating solution?

    PubMed

    Iacovidou, Eleni; Purnell, Phil; Lim, Ming K

    2018-06-15

    The exploitation of Radio Frequency Identification (RFID) for tracking and archiving the properties of structural construction components could be a potentially innovative disruption for the construction sector. This is because RFID can stimulate the reuse of construction components and reduce their wastage, hence addressing sustainability issues in the construction sector. To test the plausibility of that idea, this study explores the potential pre-conditions for RFID to facilitate construction components reuse, and develops a guidance for promoting their redistribution back to the supply chain. It also looks at how integrating RFID with Building Information Modelling (BIM) can possibly be a valuable extension of its capabilities, providing the opportunity for tracked components to be incorporated into new structures in an informed, sound way. A preliminary assessment of the strengths, weaknesses, opportunities and threats of the RFID technology is presented in order to depict its current and future potential in promoting construction components' sustainable lifecycle management, while emphasis has been laid on capturing their technical, environmental, economic and social value. Findings suggest that the collection of the right amount of information at the design-construction-deconstruction-reuse-disposal stage is crucial for RFID to become a successful innovation in the construction sector. Although a number of limitations related to the technical operability and recycling of RFID tags seem to currently hinder its uptake for structural components' lifecycle management, future technological innovations could provide solutions that would enable it to become a mainstream practice. Taken together these proposals advocate that the use of RFID and its integration with BIM can create the right environment for the development of new business models focused on sustainable resource management. These models may then unlock multiple values that are otherwise dissipated in

  8. Key Technologies and Applications of Gas Drainage in Underground Coal Mine

    NASA Astrophysics Data System (ADS)

    Zhou, Bo; Xue, Sheng; Cheng, Jiansheng; Li, Wenquan; Xiao, Jiaping

    2018-02-01

    It is the basis for the long-drilling directional drilling, precise control of the drilling trajectory and ensuring the effective extension of the drilling trajectory in the target layer. The technology can be used to complete the multi-branch hole construction and increase the effective extraction distance of the coal seam. The gas drainage and the bottom grouting reinforcement in the advanced area are realized, and the geological structure of the coal seam can be proved accurately. It is the main technical scheme for the efficient drainage of gas at home and abroad, and it is applied to the field of geological structure exploration and water exploration and other areas. At present, the data transmission method is relatively mature in the technology and application, including the mud pulse and the electromagnetic wave. Compared with the mud pulse transmission mode, the electromagnetic wave transmission mode has obvious potential in the data transmission rate and drilling fluid, and it is suitable for the coal mine. In this paper, the key technologies of the electromagnetic wave transmission mode are analyzed, including the attenuation characteristics of the electromagnetic transmission channel, the digital modulation scheme, the channel coding method and the weak signal processing technology. A coal mine under the electromagnetic wave drilling prototype is developed, and the ground transmission experiments and down hole transmission test are carried out. The main work includes the following aspects. First, the equivalent transmission line method is used to establish the electromagnetic transmission channel model of coal mine drilling while drilling, and the attenuation of the electromagnetic signal is measured when the electromagnetic channel measured. Second, the coal mine EM-MWD digital modulation method is developed. Third, the optimal linear block code which suitable for EM-MWD communication channel in coal mine is proposed. Fourth, the noise characteristics

  9. Definition of 1992 Technology Aircraft Noise Levels and the Methodology for Assessing Airplane Noise Impact of Component Noise Reduction Concepts

    NASA Technical Reports Server (NTRS)

    Kumasaka, Henry A.; Martinez, Michael M.; Weir, Donald S.

    1996-01-01

    This report describes the methodology for assessing the impact of component noise reduction on total airplane system noise. The methodology is intended to be applied to the results of individual study elements of the NASA-Advanced Subsonic Technology (AST) Noise Reduction Program, which will address the development of noise reduction concepts for specific components. Program progress will be assessed in terms of noise reduction achieved, relative to baseline levels representative of 1992 technology airplane/engine design and performance. In this report, the 1992 technology reference levels are defined for assessment models based on four airplane sizes - an average business jet and three commercial transports: a small twin, a medium sized twin, and a large quad. Study results indicate that component changes defined as program final goals for nacelle treatment and engine/airframe source noise reduction would achieve from 6-7 EPNdB reduction of total airplane noise at FAR 36 Stage 3 noise certification conditions for all of the airplane noise assessment models.

  10. Using component technologies for web based wavelet enhanced mammographic image visualization.

    PubMed

    Sakellaropoulos, P; Costaridou, L; Panayiotakis, G

    2000-01-01

    The poor contrast detectability of mammography can be dealt with by domain specific software visualization tools. Remote desktop client access and time performance limitations of a previously reported visualization tool are addressed, aiming at more efficient visualization of mammographic image resources existing in web or PACS image servers. This effort is also motivated by the fact that at present, web browsers do not support domain-specific medical image visualization. To deal with desktop client access the tool was redesigned by exploring component technologies, enabling the integration of stand alone domain specific mammographic image functionality in a web browsing environment (web adaptation). The integration method is based on ActiveX Document Server technology. ActiveX Document is a part of Object Linking and Embedding (OLE) extensible systems object technology, offering new services in existing applications. The standard DICOM 3.0 part 10 compatible image-format specification Papyrus 3.0 is supported, in addition to standard digitization formats such as TIFF. The visualization functionality of the tool has been enhanced by including a fast wavelet transform implementation, which allows for real time wavelet based contrast enhancement and denoising operations. Initial use of the tool with mammograms of various breast structures demonstrated its potential in improving visualization of diagnostic mammographic features. Web adaptation and real time wavelet processing enhance the potential of the previously reported tool in remote diagnosis and education in mammography.

  11. Using laser technological unit ALTI "Karavella" for precision components of IEP production

    NASA Astrophysics Data System (ADS)

    Labin, N. A.; Chursin, A. D.; Paramonov, V. S.; Klimenko, V. I.; Paramonova, G. M.; Kolokolov, I. S.; Vinogradov, K. Y.; Betina, L. L.; Bulychev, N. A.; Dyakov, Yu. A.; Zakharyan, R. A.; Kazaryan, M. A.; Koshelev, K. K.; Kosheleva, O. K.; Grigoryants, A. G.; Shiganov, I. N.; Krasovskii, V. I.; Sachkov, V. I.; Plyaka, P. S.; Feofanov, I. N.; Chen, C.

    2015-12-01

    The paper revealed the using of industrial production equipment ALTI "Karavella-1", "Karavella-1M", "Karavella-2" and "Karavella-2M" precision components of IEP production [1-4]. The basis for the ALTI using in the IEP have become the positive results of research and development of technologies of foil (0.01-0.2 mm) and thin sheets (0.3-1 mm) materials micromachining by pulsed radiation CVL [5, 6]. To assess the micromachining quality and precision the measuring optical microscope (UHL VMM200), projection microscope (Mitutoyo PV5100) and Carl Zeiss microscope were used.

  12. Feasibility and Testing of Additive Manufactured Components

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dehoff, Ryan R.; Hummelt, Ed; Solovyeva, Lyudmila

    2016-09-01

    This project focused on demonstrating the ability to fabricate two parts with different geometry: an arc flash interrupter and a hydraulic manifold. Eaton Corporation provided ORNL solid models, information related to tolerances and sensitive parameters of the parts and provided testing and evaluation. ORNL successfully manufactured both components, provided cost models of the manufacturing (materials, labor, time and post processing) and delivered test components for Eaton evaluation. The arc flash suppressor was fabricated using the Renishaw laser powder bed technology in CoCrMo while the manifold was produced from Ti-6Al-4V using the Arcam electron beam melting technology. These manufacturing techniques weremore » selected based on the design and geometrical tolerances required. A full-scale manifold was produced on the Arcam A2 system (nearly 12 inches tall). A portion of the manifold was also produced in the Arcam Q10 system. Although a full scale manifold could not be produced in the system, a full scale manifold is expected to have similar material properties, geometric accuracy, and surface finish as could be fabricated on an Arcam Q20 system that is capable of producing four full scale manifolds in a production environment. In addition to the manifold, mechanical test specimens, geometric tolerance artifacts, and microstructure samples were produced alongside the manifold. The development and demonstration of these two key components helped Eaton understand the impact additive manufacturing can have on many of their existing products. By working within the MDF and leveraging ORNL’s manufacturing and characterization capabilities, the work will ensure the rapid insertion and commercialization of this technology.« less

  13. Metal injection molding as enabling technology for the production of metal prosthesis components: electrochemical and in vitro characterization.

    PubMed

    Melli, Virginia; Rondelli, Gianni; Sandrini, Enrico; Altomare, Lina; Bolelli, Giovanni; Bonferroni, Benedetta; Lusvarghi, Luca; Cigada, Alberto; De Nardo, Luigi

    2013-10-01

    Industrial manufacturing of prosthesis components could take significant advantage by the introduction of new, cost-effective manufacturing technologies with near net-shape capabilities, which have been developed during the last years to fulfill the needs of different technological sectors. Among them, metal injection molding (MIM) appears particularly promising for the production of orthopedic arthroplasty components with significant cost saving. These new manufacturing technologies, which have been developed, however, strongly affect the chemicophysical structure of processed materials and their resulting properties. In order to investigate this relationship, here we evaluated the effects on electrochemical properties, ion release, and in vitro response of medical grade CoCrMo alloy processed via MIM compared to conventional processes. MIM of the CoCrMo alloy resulted in coarser polygonal grains, with largely varying sizes; however, these microstructural differences between MIM and forged/cast CoCrMo alloys showed a negligible effect on electrochemical properties. Passive current densities values observed were 0.49 µA cm(-2) for MIM specimens and 0.51 µA cm(-2) for forged CoCrMo specimens, with slightly lower transpassive potential in the MIM case; open circuit potential and Rp stationary values showed no significant differences. Moreover, in vitro biocompatibility tests resulted in cell viability levels not significantly different for MIM and conventionally processed alloys. Although preliminary, these results support the potential of MIM technology for the production of CoCrMo components of implantable devices. Copyright © 2013 Wiley Periodicals, Inc.

  14. The humoral pattern recognition molecule PTX3 is a key component of innate immunity against urinary tract infection.

    PubMed

    Jaillon, Sébastien; Moalli, Federica; Ragnarsdottir, Bryndis; Bonavita, Eduardo; Puthia, Manoj; Riva, Federica; Barbati, Elisa; Nebuloni, Manuela; Cvetko Krajinovic, Lidija; Markotic, Alemka; Valentino, Sonia; Doni, Andrea; Tartari, Silvia; Graziani, Giorgio; Montanelli, Alessandro; Delneste, Yves; Svanborg, Catharina; Garlanda, Cecilia; Mantovani, Alberto

    2014-04-17

    Immunity in the urinary tract has distinct and poorly understood pathophysiological characteristics and urinary tract infections (UTIs) are important causes of morbidity and mortality. We investigated the role of the soluble pattern recognition molecule pentraxin 3 (PTX3), a key component of the humoral arm of innate immunity, in UTIs. PTX3-deficient mice showed defective control of UTIs and exacerbated inflammation. Expression of PTX3 was induced in uroepithelial cells by uropathogenic Escherichia coli (UPEC) in a Toll-like receptor 4 (TLR4)- and MyD88-dependent manner. PTX3 enhanced UPEC phagocytosis and phagosome maturation by neutrophils. PTX3 was detected in urine of UTI patients and amounts correlated with disease severity. In cohorts of UTI-prone patients, PTX3 gene polymorphisms correlated with susceptibility to acute pyelonephritis and cystitis. These results suggest that PTX3 is an essential component of innate resistance against UTIs. Thus, the cellular and humoral arms of innate immunity exert complementary functions in mediating resistance against UTIs. Copyright © 2014 Elsevier Inc. All rights reserved.

  15. A review on several key problems of standoff trace explosives detection by optical-related technology

    NASA Astrophysics Data System (ADS)

    Chen, Zhibin; Xiao, Cheng; Xiao, Wenjian; Qin, Mengze; Liu, Xianhong

    2016-01-01

    To prevent tragic disasters caused by terror acts and warfare threats, security check personnel must be capable of discovering, distinguishing and eliminating the explosives at multiple circumstances. Standoff technology for the remote detection of explosives and their traces on contaminated surfaces is a research field that has become a heightened priority in recent years for homeland security and counter-terrorism applications. There has been a huge increase in research within this area, the improvement of standoff trace explosives detection by optical-related technology. This paper provides a consolidation of information relating to recent advances in several key problems of, without being limited to one specific research area or explosive type. Working laser wavelength of detection system is discussed. Generation and collection of explosives spectra signal are summarized. Techniques for analysing explosives spectra signal are summed up.

  16. Traditional Tales and Imaginary Contexts in Primary Design and Technology: A Case Study

    ERIC Educational Resources Information Center

    McLain, Matt; McLain, Mel; Tsai, Jess; Martin, Mike; Bell, Dawne; Wooff, David

    2017-01-01

    Working with contexts is a key component to design and technology activity and education. The most recent iteration of the national curriculum programme of study for design and technology, in England, sets out that children between the ages of 5 and 7 "should work in a range of relevant contexts" (DfE, 2013, p.193); suggested contexts…

  17. Using principal components analysis to explore competence and confidence in student nurses as users of information and communication technologies.

    PubMed

    Todhunter, Fern

    2015-07-01

    To report on the relationship between competence and confidence in nursing students as users of information and communication technologies, using principal components analysis. In nurse education, learning about and learning using information and communication technologies is well established. Nursing students are one of the undergraduate populations in higher education required to use these resources for academic work and practice learning. Previous studies showing mixed experiences influenced the choice of an exploratory study to find out about information and communication technologies competence and confidence. A 48-item survey questionnaire was administered to a volunteer sample of first- and second-year nursing students between July 2008-April 2009. The cohort ( N  =   375) represented 18·75% of first- and second-year undergraduates. A comparison between this work and subsequent studies reveal some similar ongoing issues and ways to address them. A principal components analysis (PCA) was carried out to determine the strength of the correlation between information and communication technologies competence and confidence. The aim was to show the presence of any underlying dimensions in the transformed data that would explain any variations in information and communication technologies competence and confidence. Cronbach's alpha values showed fair to good internal consistency. The five component structure gave medium to high results and explained 44·7% of the variance in the original data. Confidence had a high representation. The findings emphasized the shift towards social learning approaches for information and communication technologies. Informal social collaboration found favour with nursing students. Learning through talking, watching and listening all play a crucial role in the development of computing skills.

  18. Development and Application of the Key Technologies for the Quality Control and Inspection of National Geographical Conditions Survey Products

    NASA Astrophysics Data System (ADS)

    Zhao, Y.; Zhang, L.; Ma, W.; Zhang, P.; Zhao, T.

    2018-04-01

    The First National Geographical Condition Survey is a predecessor task to dynamically master basic situations of the nature, ecology and human activities on the earth's surface and it is the brand-new mapping geographic information engineering. In order to ensure comprehensive, real and accurate survey results and achieve the quality management target which the qualified rate is 100 % and the yield is more than 80 %, it is necessary to carry out the quality control and result inspection for national geographical conditions survey on a national scale. To ensure that achievement quality meets quality target requirements, this paper develops the key technology method of "five-in-one" quality control that is constituted by "quality control system of national geographical condition survey, quality inspection technology system, quality evaluation system, quality inspection information management system and national linked quality control institutions" by aiming at large scale, wide coverage range, more undertaking units, more management levels, technical updating, more production process and obvious regional differences in the national geographical condition survey and combining with novel achievement manifestation, complicated dependency, more special reference data, and large data size. This project fully considering the domestic and foreign related research results and production practice experience, combined with the technology development and the needs of the production, it stipulates the inspection methods and technical requirements of each stage in the quality inspection of the geographical condition survey results, and extends the traditional inspection and acceptance technology, and solves the key technologies that are badly needed in the first national geographic survey.

  19. A research project to develop and evaluate a technical education component on materials technology for orientation to space-age technology

    NASA Technical Reports Server (NTRS)

    Jacobs, J. A.

    1976-01-01

    A project was initiated to develop, implement, and evaluate a prototype component for self-pacing, individualized instruction on basic materials science. Results of this project indicate that systematically developed, self-paced instruction provides an effective means for orienting nontraditional college students and secondary students, especially minorities, to both engineering technology and basic materials science. In addition, students using such a system gain greater chances for mastering subject matter than with conventional modes of instruction.

  20. Technology Maturation in Preparation for the Cryogenic Propellant Storage and Transfer (CPST) Technology Demonstration Mission (TDM)

    NASA Technical Reports Server (NTRS)

    Meyer, Michael L.; Doherty, Michael P.; Moder, Jeffrey P.

    2014-01-01

    In support of its goal to find an innovative path for human space exploration, NASA embarked on the Cryogenic Propellant Storage and Transfer (CPST) Project, a Technology Demonstration Mission (TDM) to test and validate key cryogenic capabilities and technologies required for future exploration elements, opening up the architecture for large in-space cryogenic propulsion stages and propellant depots. Recognizing that key Cryogenic Fluid Management (CFM) technologies anticipated for on-orbit (flight) demonstration would benefit from additional maturation to a readiness level appropriate for infusion into the design of the flight demonstration, the NASA Headquarters Space Technology Mission Directorate (STMD) authorized funding for a one-year technology maturation phase of the CPST project. The strategy, proposed by the CPST Project Manager, focused on maturation through modeling, concept studies, and ground tests of the storage and fluid transfer of CFM technology sub-elements and components that were lower than a Technology Readiness Level (TRL) of 5. A technology maturation plan (TMP) was subsequently approved which described: the CFM technologies selected for maturation, the ground testing approach to be used, quantified success criteria of the technologies, hardware and data deliverables, and a deliverable to provide an assessment of the technology readiness after completion of the test, study or modeling activity. The specific technologies selected were grouped into five major categories: thick multilayer insulation, tank applied active thermal control, cryogenic fluid transfer, propellant gauging, and analytical tool development. Based on the success of the technology maturation efforts, the CPST project was approved to proceed to flight system development.

  1. Applying the System Component and Operationally Relevant Evaluation (SCORE) Framework to Evaluate Advanced Military Technologies

    DTIC Science & Technology

    2010-03-01

    and charac- terize the actions taken by the soldier (e.g., running, walking, climbing stairs ). Real-time image capture and exchange N The ability of...multimedia information sharing among soldiers in the field, two-way speech translation systems, and autonomous robotic platforms. Key words: Emerging...soldiers in the field, two-way speech translation systems, and autonomous robotic platforms. It has been the foundation for 10 technology evaluations

  2. Technology readiness levels for the new millennium program

    NASA Technical Reports Server (NTRS)

    Moynihan, P. I.; Minning, C. P.; Stocky, J. F.

    2003-01-01

    NASA's New Millennium Program (NMP) seeks to advance space exploration by providing an in-space validating mechanism to verify the maturity of promising advanced technologies that cannot be adequately validated with Earth-based testing alone. In meeting this objective, NMP uses NASA Technology Readiness Levels (TRL) as key indicators of technology advancement and assesses development progress against this generalized metric. By providing an opportunity for in-space validation, NMP can mature a suitable advanced technology from TRL 4 (component and/or breadboard validation in laboratory environment) to a TRL 7 (system prototype demonstrated in an Earth-based space environment). Spaceflight technology comprises a myriad of categories, types, and functions, and as each individual technology emerges, a consistent interpretation of its specific state of technological advancement relative to other technologies is problematic.

  3. Key success factors of health research centers: A mixed method study.

    PubMed

    Tofighi, Shahram; Teymourzadeh, Ehsan; Heydari, Majid

    2017-08-01

    In order to achieve success in future goals and activities, health research centers are required to identify their key success factors. This study aimed to extract and rank the factors affecting the success of research centers at one of the medical universities in Iran. This study is a mixed method (qualitative-quantitative) study, which was conducted between May to October in 2016. The study setting was 22 health research centers. In qualitative phase, we extracted the factors affecting the success in research centers through purposeful interviews with 10 experts of centers, and classified them into themes and sub-themes. In the quantitative phase, we prepared a questionnaire and scored and ranked the factors recognized by 54 of the study samples by Friedman test. Nine themes and 42 sub-themes were identified. Themes included: strategic orientation, management, human capital, support, projects, infrastructure, communications and collaboration, paradigm and innovation and they were rated respectively as components of success in research centers. Among the 42 identified factors, 10 factors were ranked respectively as the key factors of success, and included: science and technology road map, strategic plan, evaluation indexes, committed human resources, scientific evaluation of members and centers, innovation in research and implementation, financial support, capable researchers, equipment infrastructure and teamwork. According to the results, the strategic orientation was the most important component in the success of research centers. Therefore, managers and authorities of research centers should pay more attention to strategic areas in future planning, including the science and technology road map and strategic plan.

  4. Key success factors of health research centers: A mixed method study

    PubMed Central

    Tofighi, Shahram; Teymourzadeh, Ehsan; Heydari, Majid

    2017-01-01

    Background In order to achieve success in future goals and activities, health research centers are required to identify their key success factors. Objective This study aimed to extract and rank the factors affecting the success of research centers at one of the medical universities in Iran. Methods This study is a mixed method (qualitative-quantitative) study, which was conducted between May to October in 2016. The study setting was 22 health research centers. In qualitative phase, we extracted the factors affecting the success in research centers through purposeful interviews with 10 experts of centers, and classified them into themes and sub-themes. In the quantitative phase, we prepared a questionnaire and scored and ranked the factors recognized by 54 of the study samples by Friedman test. Results Nine themes and 42 sub-themes were identified. Themes included: strategic orientation, management, human capital, support, projects, infrastructure, communications and collaboration, paradigm and innovation and they were rated respectively as components of success in research centers. Among the 42 identified factors, 10 factors were ranked respectively as the key factors of success, and included: science and technology road map, strategic plan, evaluation indexes, committed human resources, scientific evaluation of members and centers, innovation in research and implementation, financial support, capable researchers, equipment infrastructure and teamwork. Conclusion According to the results, the strategic orientation was the most important component in the success of research centers. Therefore, managers and authorities of research centers should pay more attention to strategic areas in future planning, including the science and technology road map and strategic plan. PMID:28979733

  5. From Domain Specific Languages to DEVS Components: Application to Cognitive M&S

    DTIC Science & Technology

    2011-04-01

    AND SUBTITLE From Domain Specific Languages to DEVS Components: Application to Cognitive M&S 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ...that is devoid of any DEVS and programming language constructs (Figure 4). The key idea being domain specialists need not delve in the DEVS world to...DSL. DSLs can be created using many available tools and technologies such as: Generic Modeling Environment (GME) [23], Xtext, Ruby, Scala and many

  6. Heat Treatment Used to Strengthen Enabling Coating Technology for Oil-Free Turbomachinery

    NASA Technical Reports Server (NTRS)

    Edmonds, Brian J.; DellaCorte, Christopher

    2002-01-01

    The PS304 high-temperature solid lubricant coating is a key enabling technology for Oil- Free turbomachinery propulsion and power systems. Breakthroughs in the performance of advanced foil air bearings and improvements in computer-based finite element modeling techniques are the key technologies enabling the development of Oil-Free aircraft engines being pursued by the Oil-Free Turbomachinery team at the NASA Glenn Research Center. PS304 is a plasma spray coating applied to the surface of shafts operating against foil air bearings or in any other component requiring solid lubrication at high temperatures, where conventional materials such as graphite cannot function.

  7. Innovations in Balloon Catheter Technology in Rhinology.

    PubMed

    D'Anza, Brian; Sindwani, Raj; Woodard, Troy D

    2017-06-01

    Since being introduced more than 10 years ago, balloon catheter technology (BCT) has undergone several generations of innovations. From construction to utilization, there has been a myriad of advancements in balloon technology. The ergonomics of the balloon dilation systems have improved with a focus on limiting the extra assembly. "Hybrid" BCT procedures have shown promise in mucosal preservation, including treating isolated complex frontal disease. Multiple randomized clinical trials report improved long-term outcomes in stand-alone BCT, including in-office use. The ever-expanding technological innovations ensure BCT will be a key component in the armamentarium of the modern sinus surgeon. Copyright © 2017 Elsevier Inc. All rights reserved.

  8. Component of Caramel Food Coloring, THI, Causes Lymphopenia Indirectly via a Key Metabolic Intermediate.

    PubMed

    Ohtoyo, Mamoru; Machinaga, Nobuo; Inoue, Ryotaku; Hagihara, Katsunobu; Yuita, Hiroshi; Tamura, Masakazu; Hashimoto, Ryuji; Chiba, Jun; Muro, Fumihito; Watanabe, Jun; Kobayashi, Yoshimasa; Abe, Koji; Kita, Yasuo; Nagasaki, Miyuki; Shimozato, Takaichi

    2016-05-19

    Caramel color is widely used in the food industry, and its many variations are generally considered to be safe. It has been known for a long time that THI (2-acetyl-4-(tetrahydroxybutyl)imidazole), a component of caramel color III, causes lymphopenia in animals through sphingosine 1-phosphate (S1P) lyase (S1PL) inhibition. However, this mechanism of action has not been fully validated because THI does not inhibit S1PL in vitro. To reconcile this situation, we examined molecular details of THI mechanism of action using "smaller" THI derivatives. We identified a bioactive derivative, A6770, which has the same lymphopenic effect as THI via S1PL inhibition. In the case of A6770 we observe this effect both in vitro and in vivo, and demonstrate that A6770 is phosphorylated and inhibits S1PL in the same way as 4-deoxypyridoxine. In addition, A6770 was detected in rat plasma following oral administration of THI, suggesting that A6770 is a key metabolic intermediate of THI. Copyright © 2016 Elsevier Ltd. All rights reserved.

  9. Controls and Health Management Technologies for Intelligent Aerospace Propulsion Systems

    NASA Technical Reports Server (NTRS)

    Garg, Sanjay

    2004-01-01

    With the increased emphasis on aircraft safety, enhanced performance and affordability, and the need to reduce the environmental impact of aircraft, there are many new challenges being faced by the designers of aircraft propulsion systems. The Controls and Dynamics Technology Branch at NASA (National Aeronautics and Space Administration) Glenn Research Center (GRC) in Cleveland, Ohio, is leading and participating in various projects in partnership with other organizations within GRC and across NASA, the U.S. aerospace industry, and academia to develop advanced controls and health management technologies that will help meet these challenges through the concept of an Intelligent Engine. The key enabling technologies for an Intelligent Engine are the increased efficiencies of components through active control, advanced diagnostics and prognostics integrated with intelligent engine control to enhance component life, and distributed control with smart sensors and actuators in an adaptive fault tolerant architecture. This paper describes the current activities of the Controls and Dynamics Technology Branch in the areas of active component control and propulsion system intelligent control, and presents some recent analytical and experimental results in these areas.

  10. Development of components for IFOG-based inertial measurement units using polymer waveguide fabrication technologies

    NASA Astrophysics Data System (ADS)

    Ashley, P. R.; Temmen, M. G.; Diffey, W. M.; Sanghadasa, M.; Bramson, M. D.

    2007-10-01

    Active and passive polymer materials have been successfully used in the development of highly accurate, compact and low cost guided-wave components: an optical transceiver and a phase modulator, for inertial measurement units (IMUs) based on the interferometric fibre optic gyroscope (IFOG) technology for precision guidance in navigation systems. High performance and low noise transceivers with high optical power and good spectral quality were fabricated using a silicon-bench architecture. Low loss phase modulators with low halfwave drive voltage (Vπ) have been fabricated with a backscatter compensated design using polarizing waveguides consisting of CLD- and FTC-type high performance electro-optic (E-O) chromophores. Gyro bias stability of less than 0.02° h-1 has been demonstrated with these guided-wave components.

  11. Key Emerging Technologies for Postsecondary Education

    ERIC Educational Resources Information Center

    Johnson, Laurence F.; Levine, Alan; Smith, Rachel S.; Haywood, Keene

    2010-01-01

    The annual "Horizon Report" describes the continuing work of the New Media Consortium's Horizon Project, a qualitative research project established in 2002 that identifies and describes emerging technologies likely to have a large impact on teaching, learning, or creative inquiry on college and university campuses within the next five years. The…

  12. Key Emerging Technologies for Postsecondary Education

    ERIC Educational Resources Information Center

    Johnson, Laurence F.; Levine, Alan; Smith, Rachel S.; Haywood, Keene

    2010-01-01

    The annual "Horizon Report" describes the continuing work of the New Media Consortium's Horizon Project, a qualitative research project established in 2002 that identifies and describes emerging technologies likely to have a large impact on teaching, learning, or creative inquiry on college and university campuses within the next five years. This…

  13. Key Technology Research on Open Architecture for The Sharing of Heterogeneous Geographic Analysis Models

    NASA Astrophysics Data System (ADS)

    Yue, S. S.; Wen, Y. N.; Lv, G. N.; Hu, D.

    2013-10-01

    In recent years, the increasing development of cloud computing technologies laid critical foundation for efficiently solving complicated geographic issues. However, it is still difficult to realize the cooperative operation of massive heterogeneous geographical models. Traditional cloud architecture is apt to provide centralized solution to end users, while all the required resources are often offered by large enterprises or special agencies. Thus, it's a closed framework from the perspective of resource utilization. Solving comprehensive geographic issues requires integrating multifarious heterogeneous geographical models and data. In this case, an open computing platform is in need, with which the model owners can package and deploy their models into cloud conveniently, while model users can search, access and utilize those models with cloud facility. Based on this concept, the open cloud service strategies for the sharing of heterogeneous geographic analysis models is studied in this article. The key technology: unified cloud interface strategy, sharing platform based on cloud service, and computing platform based on cloud service are discussed in detail, and related experiments are conducted for further verification.

  14. Multicomponent reactions provide key molecules for secret communication.

    PubMed

    Boukis, Andreas C; Reiter, Kevin; Frölich, Maximiliane; Hofheinz, Dennis; Meier, Michael A R

    2018-04-12

    A convenient and inherently more secure communication channel for encoding messages via specifically designed molecular keys is introduced by combining advanced encryption standard cryptography with molecular steganography. The necessary molecular keys require large structural diversity, thus suggesting the application of multicomponent reactions. Herein, the Ugi four-component reaction of perfluorinated acids is utilized to establish an exemplary database consisting of 130 commercially available components. Considering all permutations, this combinatorial approach can unambiguously provide 500,000 molecular keys in only one synthetic procedure per key. The molecular keys are transferred nondigitally and concealed by either adsorption onto paper, coffee, tea or sugar as well as by dissolution in a perfume or in blood. Re-isolation and purification from these disguises is simplified by the perfluorinated sidechains of the molecular keys. High resolution tandem mass spectrometry can unequivocally determine the molecular structure and thus the identity of the key for a subsequent decryption of an encoded message.

  15. e-Phys: a suite of intracellular neurophysiology programs integrating COM (component object model) technologies.

    PubMed

    Nguyen, Quoc-Thang; Miledi, Ricardo

    2003-09-30

    Current computer programs for intracellular recordings often lack advanced data management, are usually incompatible with other applications and are also difficult to adapt to new experiments. We have addressed these shortcomings in e-Phys, a suite of electrophysiology applications for intracellular recordings. The programs in e-Phys use Component Object Model (COM) technologies available in the Microsoft Windows operating system to provide enhanced data storage, increased interoperability between e-Phys and other COM-aware applications, and easy customization of data acquisition and analysis thanks to a script-based integrated programming environment. Data files are extensible, hierarchically organized and integrated in the Windows shell by using the Structured Storage technology. Data transfers to and from other programs are facilitated by implementing the ActiveX Automation standard and distributed COM (DCOM). ActiveX Scripting allows experimenters to write their own event-driven acquisition and analysis programs in the VBScript language from within e-Phys. Scripts can reuse components available from other programs on other machines to create distributed meta-applications. This paper describes the main features of e-Phys and how this package was used to determine the effect of the atypical antipsychotic drug clozapine on synaptic transmission at the neuromuscular junction.

  16. High-efficient extraction of principal medicinal components from fresh Phellodendron bark (cortex phellodendri).

    PubMed

    Xu, Keqin; He, Gongxiu; Qin, Jieming; Cheng, Xuexiang; He, Hanjie; Zhang, Dangquan; Peng, Wanxi

    2018-05-01

    There are three key medicinal components (phellodendrine, berberine and palmatine) in the extracts of Phellodendron bark, as one of the fundamental herbs of traditional Chinese medicine. Different extraction methods and solvent combinations were investigated to obtain the optimal technologies for high-efficient extraction of these medicinal components. The results showed that combined solvents have higher extracting effect of phellodendrine, berberine and palmatine than single solvent, and the effect of ultrasonic extraction is distinctly better than those of distillation and soxhlet extraction. The hydrochloric acid/methanol-ultrasonic extraction has the best effect for three medicinal components of fresh Phellodendron bark, providing an extraction yield of 103.12 mg/g berberine, 24.41 mg/g phellodendrine, 1.25 mg/g palmatine.

  17. A Selected Review of the Underpinnings of Ethics for Human Performance Technology Professionals--Part One: Key Ethical Theories and Research.

    ERIC Educational Resources Information Center

    Dean, Peter J.

    1993-01-01

    Provides a review of the key ethical theories and relevant empirical research relating to the practice of human performance technology. Topics addressed include ethics, morals, business ethics, ethics officers, empiricism versus normative ethical theory, consequentialism, utilitarianism, nonconsequentialism, Kohlberg model of cognitive moral…

  18. Direct transcriptional activation of BT genes by NLP transcription factors is a key component of the nitrate response in Arabidopsis.

    PubMed

    Sato, Takeo; Maekawa, Shugo; Konishi, Mineko; Yoshioka, Nozomi; Sasaki, Yuki; Maeda, Haruna; Ishida, Tetsuya; Kato, Yuki; Yamaguchi, Junji; Yanagisawa, Shuichi

    2017-01-29

    Nitrate modulates growth and development, functioning as a nutrient signal in plants. Although many changes in physiological processes in response to nitrate have been well characterized as nitrate responses, the molecular mechanisms underlying the nitrate response are not yet fully understood. Here, we show that NLP transcription factors, which are key regulators of the nitrate response, directly activate the nitrate-inducible expression of BT1 and BT2 encoding putative scaffold proteins with a plant-specific domain structure in Arabidopsis. Interestingly, the 35S promoter-driven expression of BT2 partially rescued growth inhibition caused by reductions in NLP activity in Arabidopsis. Furthermore, simultaneous disruption of BT1 and BT2 affected nitrate-dependent lateral root development. These results suggest that direct activation of BT1 and BT2 by NLP transcriptional activators is a key component of the molecular mechanism underlying the nitrate response in Arabidopsis. Copyright © 2016 Elsevier Inc. All rights reserved.

  19. Coordination between veterinary services and other relevant authorities: a key component of good public governance.

    PubMed

    Bellemain, V

    2012-08-01

    Coordination between Veterinary Services and other relevant authorities is a key component of good public governance, especially for effective action and optimal management of available resources. The importance of good coordination is reflected in the World Organisation for Animal Health'Tool forthe Evaluation of Performance of Veterinary Services', which includes a critical competency on coordination. Many partners from technical, administrative and legal fields are involved. The degree of formalisation of coordination tends to depend on a country's level of organisation and development. Contingency plans against avian influenza led to breakthroughs in many countries in the mid-2000s. While interpersonal relationships remain vital, not everything should hinge on them. Organisation and management are critical to operational efficiency. The distribution of responsibilities needs to be defined clearly, avoiding duplication and areas of conflict. Lead authorities should be designated according to subject (Veterinary Services in animal health areas) and endowed with the necessary legitimacy. Lead authorities will be responsible for coordinating the drafting and updating of the relevant documents: agreements between authorities, contingency plans, standard operating procedures, etc.

  20. Development of manufacturing processes: improved technology for ceramic engine components. Monthly report, August 1977

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Craig, D.F.; Taylor, A.J.; Weber, G.W.

    Progress is described in a research program to develop advanced tooling concepts, processing techniques, and related technology for the economical high-volume manufacture of ceramic engine components. Because of the success of the initial fabrication effort for hot pressing fully dense ceramic turbine blades to shape and/or contour, the effort has been extended to include the fabrication of more complex shapes and the evaluation of alternative pressure-assisted, high-temperature, consolidation methods.

  1. Efficient key pathway mining: combining networks and OMICS data.

    PubMed

    Alcaraz, Nicolas; Friedrich, Tobias; Kötzing, Timo; Krohmer, Anton; Müller, Joachim; Pauling, Josch; Baumbach, Jan

    2012-07-01

    Systems biology has emerged over the last decade. Driven by the advances in sophisticated measurement technology the research community generated huge molecular biology data sets. These comprise rather static data on the interplay of biological entities, for instance protein-protein interaction network data, as well as quite dynamic data collected for studying the behavior of individual cells or tissues in accordance with changing environmental conditions, such as DNA microarrays or RNA sequencing. Here we bring the two different data types together in order to gain higher level knowledge. We introduce a significantly improved version of the KeyPathwayMiner software framework. Given a biological network modelled as a graph and a set of expression studies, KeyPathwayMiner efficiently finds and visualizes connected sub-networks where most components are expressed in most cases. It finds all maximal connected sub-networks where all nodes but k exceptions are expressed in all experimental studies but at most l exceptions. We demonstrate the power of the new approach by comparing it to similar approaches with gene expression data previously used to study Huntington's disease. In addition, we demonstrate KeyPathwayMiner's flexibility and applicability to non-array data by analyzing genome-scale DNA methylation profiles from colorectal tumor cancer patients. KeyPathwayMiner release 2 is available as a Cytoscape plugin and online at http://keypathwayminer.mpi-inf.mpg.de.

  2. Space division multiplexing chip-to-chip quantum key distribution.

    PubMed

    Bacco, Davide; Ding, Yunhong; Dalgaard, Kjeld; Rottwitt, Karsten; Oxenløwe, Leif Katsuo

    2017-09-29

    Quantum cryptography is set to become a key technology for future secure communications. However, to get maximum benefit in communication networks, transmission links will need to be shared among several quantum keys for several independent users. Such links will enable switching in quantum network nodes of the quantum keys to their respective destinations. In this paper we present an experimental demonstration of a photonic integrated silicon chip quantum key distribution protocols based on space division multiplexing (SDM), through multicore fiber technology. Parallel and independent quantum keys are obtained, which are useful in crypto-systems and future quantum network.

  3. Research gaps and technology needs in development of PHM for passive AdvSMR components

    NASA Astrophysics Data System (ADS)

    Meyer, Ryan M.; Ramuhalli, Pradeep; Coble, Jamie B.; Hirt, Evelyn H.; Mitchell, Mark R.; Wootan, David W.; Berglin, Eric J.; Bond, Leonard J.; Henagar, Chuck H., Jr.

    2014-02-01

    Advanced small modular reactors (AdvSMRs), which are based on modularization of advanced reactor concepts, may provide a longer-term alternative to traditional light-water reactors and near-term small modular reactors (SMRs), which are based on integral pressurized water reactor (iPWR) concepts. SMRs are challenged economically because of losses in economy of scale; thus, there is increased motivation to reduce the controllable operations and maintenance costs through automation technologies including prognostics health management (PHM) systems. In this regard, PHM systems have the potential to play a vital role in supporting the deployment of AdvSMRs and face several unique challenges with respect to implementation for passive AdvSMR components. This paper presents a summary of a research gaps and technical needs assessment performed for implementation of PHM for passive AdvSMR components.

  4. Key Emerging Technologies for Elementary and Secondary Education

    ERIC Educational Resources Information Center

    Johnson, Laurence F.; Levine, Alan; Smith, Rachel S.; Haywood, Keene

    2010-01-01

    The Horizon Report series is the most visible outcome of the New Media Consortium's Horizon Project, an ongoing research effort that identifies and describes emerging technologies likely to have a large impact on teaching, learning, research, or creative expression within education around the globe. The report examines emerging technologies for…

  5. Key Emerging Technologies for Elementary and Secondary Education

    ERIC Educational Resources Information Center

    Johnson, Laurence F.; Levine, Alan; Smith, Rachel S.; Haywood, Keene

    2010-01-01

    The "Horizon Report" series is the most visible outcome of the New Media Consortium's Horizon Project, an ongoing research effort that identifies and describes emerging technologies likely to have a large impact on teaching, learning, research, or creative expression within education around the globe. The report examines emerging technologies for…

  6. Summary of Key Issues Raised in the Technology for Early Awareness of Addiction and Mental Illness (TEAAM-I) Meeting.

    PubMed

    Baumel, Amit; Baker, Justin; Birnbaum, Michael L; Christensen, Helen; De Choudhury, Munmun; Mohr, David C; Muench, Fred; Schlosser, Danielle; Titov, Nick; Kane, John M

    2018-05-01

    Technology provides an unparalleled opportunity to remove barriers to earlier identification and engagement in services for mental and addictive disorders by reaching people earlier in the course of illness and providing links to just-in-time, cost-effective interventions. Achieving this opportunity, however, requires stakeholders to challenge underlying assumptions about traditional pathways to mental health care. In this Open Forum, the authors highlight key issues discussed in the Technology for Early Awareness of Addiction and Mental Illness (TEAAM-I) meeting-held October 13-14, 2016, in New York City-that are related to three identified areas in which technology provides important and unique opportunities to advance early identification, increase service engagement, and decrease the duration of untreated mental and addictive disorders.

  7. Smart image sensors: an emerging key technology for advanced optical measurement and microsystems

    NASA Astrophysics Data System (ADS)

    Seitz, Peter

    1996-08-01

    Optical microsystems typically include photosensitive devices, analog preprocessing circuitry and digital signal processing electronics. The advances in semiconductor technology have made it possible today to integrate all photosensitive and electronical devices on one 'smart image sensor' or photo-ASIC (application-specific integrated circuits containing photosensitive elements). It is even possible to provide each 'smart pixel' with additional photoelectronic functionality, without compromising the fill factor substantially. This technological capability is the basis for advanced cameras and optical microsystems showing novel on-chip functionality: Single-chip cameras with on- chip analog-to-digital converters for less than $10 are advertised; image sensors have been developed including novel functionality such as real-time selectable pixel size and shape, the capability of performing arbitrary convolutions simultaneously with the exposure, as well as variable, programmable offset and sensitivity of the pixels leading to image sensors with a dynamic range exceeding 150 dB. Smart image sensors have been demonstrated offering synchronous detection and demodulation capabilities in each pixel (lock-in CCD), and conventional image sensors are combined with an on-chip digital processor for complete, single-chip image acquisition and processing systems. Technological problems of the monolithic integration of smart image sensors include offset non-uniformities, temperature variations of electronic properties, imperfect matching of circuit parameters, etc. These problems can often be overcome either by designing additional compensation circuitry or by providing digital correction routines. Where necessary for technological or economic reasons, smart image sensors can also be combined with or realized as hybrids, making use of commercially available electronic components. It is concluded that the possibilities offered by custom smart image sensors will influence the design

  8. [The Key Technology Study on Cloud Computing Platform for ECG Monitoring Based on Regional Internet of Things].

    PubMed

    Yang, Shu; Qiu, Yuyan; Shi, Bo

    2016-09-01

    This paper explores the methods of building the internet of things of a regional ECG monitoring, focused on the implementation of ECG monitoring center based on cloud computing platform. It analyzes implementation principles of automatic identifi cation in the types of arrhythmia. It also studies the system architecture and key techniques of cloud computing platform, including server load balancing technology, reliable storage of massive smalfi les and the implications of quick search function.

  9. The approach for shortest paths in fire succor based on component GIS technology

    NASA Astrophysics Data System (ADS)

    Han, Jie; Zhao, Yong; Dai, K. W.

    2007-06-01

    Fire safety is an important issue for the national economy and people's living. Efficiency and exactness of fire department succor directly relate to safety of peoples' lives and property. Many disadvantages of the traditional fire system have been emerged in practical applications. The preparation of pumpers is guided by wireless communication or wire communication, so its real-time and accurate performances are much poorer. The information about the reported fire, such as the position, disaster and map, et al., for alarm and command was processed by persons, which slows the reaction speed and delays the combat opportunity. In order to solve these disadvantages, it has an important role to construct a modern fire command center based on high technology. The construction of modern fire command center can realize the modernization and automation of fire command and management. It will play a great role in protecting safety of peoples' lives and property. The center can enhance battle ability and can reduce the direct and indirect loss of fire damage at most. With the development of science technology, Geographic Information System (GIS) has becoming a new information industry for hardware production, software development, data collection, space analysis and counseling. With the popularization of computers and the development of GIS, GIS has gained increasing broad applications for its strong functionality. Network analysis is one of the most important functions of GIS, and the most elementary and pivotal issue of network analysis is the calculation of shortest paths. The shortest paths are mostly applied to some emergent systems such as 119 fire alarms. These systems mainly require that the computation time of the optimal path should be 1-3 seconds. And during traveling, the next running path of the vehicles should be calculated in time. So the implement of the shortest paths must have a high efficiency. In this paper, the component GIS technology was applied to

  10. Application of acoustic surface wave filter-beam lead component technology to deep space multimission hardware design

    NASA Technical Reports Server (NTRS)

    Kermode, A. W.; Boreham, J. F.

    1974-01-01

    This paper discusses the utilization of acoustic surface wave filters, beam lead components, and thin film metallized ceramic substrate technology as applied to the design of deep space, long-life, multimission transponder. The specific design to be presented is for a second mixer local oscillator module, operating at frequencies as high as 249 MHz.

  11. Analysis of Unmanned Aerial Vehicle (UAV) hyperspectral remote sensing monitoring key technology in coastal wetland

    NASA Astrophysics Data System (ADS)

    Ma, Yi; Zhang, Jie; Zhang, Jingyu

    2016-01-01

    The coastal wetland, a transitional zone between terrestrial ecosystems and marine ecosystems, is the type of great value to ecosystem services. For the recent 3 decades, area of the coastal wetland is decreasing and the ecological function is gradually degraded with the rapid development of economy, which restricts the sustainable development of economy and society in the coastal areas of China in turn. It is a major demand of the national reality to carry out the monitoring of coastal wetlands, to master the distribution and dynamic change. UAV, namely unmanned aerial vehicle, is a new platform for remote sensing. Compared with the traditional satellite and manned aerial remote sensing, it has the advantage of flexible implementation, no cloud cover, strong initiative and low cost. Image-spectrum merging is one character of high spectral remote sensing. At the same time of imaging, the spectral curve of each pixel is obtained, which is suitable for quantitative remote sensing, fine classification and target detection. Aimed at the frontier and hotspot of remote sensing monitoring technology, and faced the demand of the coastal wetland monitoring, this paper used UAV and the new remote sensor of high spectral imaging instrument to carry out the analysis of the key technologies of monitoring coastal wetlands by UAV on the basis of the current situation in overseas and domestic and the analysis of developing trend. According to the characteristic of airborne hyperspectral data on UAV, that is "three high and one many", the key technology research that should develop are promoted as follows: 1) the atmosphere correction of the UAV hyperspectral in coastal wetlands under the circumstance of complex underlying surface and variable geometry, 2) the best observation scale and scale transformation method of the UAV platform while monitoring the coastal wetland features, 3) the classification and detection method of typical features with high precision from multi scale

  12. PGY-1 surgery preparatory course design: identification of key curricular components.

    PubMed

    Antonoff, Mara B; D'Cunha, Jonathan

    2011-01-01

    The importance of preparing senior medical students (SMS) for surgical internship is clear, and initiatives to standardize such curricula are of national interest. Less clear, however, are the specific subject areas most important for inclusion in such courses. In this study, we aimed to identify key curricular components in the development of a PGY-1 Surgery Preparatory Course. A month-long PGY-1 preparatory course was offered to SMS entering surgical residencies, consisting of 55 sessions providing instruction in 3 main areas: 19 Ward Management Tasks (WMT), 12 Operative and Technical Skills (OTS), and 4 Professionalism Skillsets (PS). To determine curricular topics most valued and needed by students, data were reviewed from precourse and postcourse surveys, knowledge tests, and performance examinations. Pretest/posttest scores were compared using t-tests, α = 0.05. In all, 22 SMS enrolled in the course. Prior to course participation, students placed greatest importance on WMT (4.35 ± 0.05) over OTS (4.09 ± 0.06) and PS (3.90 ± 0.15), p < 0.05. Precourse confidence levels were lowest in WMT (2.28 ± 0.12), versus OTS (2.41 ± 0.20) and PS (3.50 ± 0.30). Mean pretest scores were 54.8 ± 2.1% in WMT and 82.7 ± 2.5% in OTS, with significant improvement to 82.2 ± 1.9% and 93.2 ± 1.3%, respectively (p < 0.05 for both), further showing greater need for instruction in WMT. SMS participating in a PGY-1 Surgery Preparatory Course identified WMT as more important than OTS and PS. Further, they demonstrated the lowest precourse confidence in this area and found that course participation most dramatically improved their perceived ability to execute these types of tasks. As efforts continue to formalize the transition from medical school to surgical residency, these findings will be instrumental in developing standardized curricula. Copyright © 2011 Association of Program Directors in Surgery. Published by Elsevier Inc. All rights reserved.

  13. FPGA based digital phase-coding quantum key distribution system

    NASA Astrophysics Data System (ADS)

    Lu, XiaoMing; Zhang, LiJun; Wang, YongGang; Chen, Wei; Huang, DaJun; Li, Deng; Wang, Shuang; He, DeYong; Yin, ZhenQiang; Zhou, Yu; Hui, Cong; Han, ZhengFu

    2015-12-01

    Quantum key distribution (QKD) is a technology with the potential capability to achieve information-theoretic security. Phasecoding is an important approach to develop practical QKD systems in fiber channel. In order to improve the phase-coding modulation rate, we proposed a new digital-modulation method in this paper and constructed a compact and robust prototype of QKD system using currently available components in our lab to demonstrate the effectiveness of the method. The system was deployed in laboratory environment over a 50 km fiber and continuously operated during 87 h without manual interaction. The quantum bit error rate (QBER) of the system was stable with an average value of 3.22% and the secure key generation rate is 8.91 kbps. Although the modulation rate of the photon in the demo system was only 200 MHz, which was limited by the Faraday-Michelson interferometer (FMI) structure, the proposed method and the field programmable gate array (FPGA) based electronics scheme have a great potential for high speed QKD systems with Giga-bits/second modulation rate.

  14. Nonribosomal peptides, key biocontrol components for Pseudomonas fluorescens In5, isolated from a Greenlandic suppressive soil.

    PubMed

    Michelsen, Charlotte F; Watrous, Jeramie; Glaring, Mikkel A; Kersten, Roland; Koyama, Nobuhiro; Dorrestein, Pieter C; Stougaard, Peter

    2015-03-17

    Potatoes are cultivated in southwest Greenland without the use of pesticides and with limited crop rotation. Despite the fact that plant-pathogenic fungi are present, no severe-disease outbreaks have yet been observed. In this report, we document that a potato soil at Inneruulalik in southern Greenland is suppressive against Rhizoctonia solani Ag3 and uncover the suppressive antifungal mechanism of a highly potent biocontrol bacterium, Pseudomonas fluorescens In5, isolated from the suppressive potato soil. A combination of molecular genetics, genomics, and matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) imaging mass spectrometry (IMS) revealed an antifungal genomic island in P. fluorescens In5 encoding two nonribosomal peptides, nunamycin and nunapeptin, which are key components for the biocontrol activity by strain In5 in vitro and in soil microcosm experiments. Furthermore, complex microbial behaviors were highlighted. Whereas nunamycin was demonstrated to inhibit the mycelial growth of R. solani Ag3, but not that of Pythium aphanidermatum, nunapeptin instead inhibited P. aphanidermatum but not R. solani Ag3. Moreover, the synthesis of nunamycin by P. fluorescens In5 was inhibited in the presence of P. aphanidermatum. Further characterization of the two peptides revealed nunamycin to be a monochlorinated 9-amino-acid cyclic lipopeptide with similarity to members of the syringomycin group, whereas nunapeptin was a 22-amino-acid cyclic lipopeptide with similarity to corpeptin and syringopeptin. Crop rotation and systematic pest management are used to only a limited extent in Greenlandic potato farming. Nonetheless, although plant-pathogenic fungi are present in the soil, the farmers do not experience major plant disease outbreaks. Here, we show that a Greenlandic potato soil is suppressive against Rhizoctonia solani, and we unravel the key biocontrol components for Pseudomonas fluorescens In5, one of the potent biocontrol bacteria

  15. Review of Maintenance and Repair Times for Components in Technological Facilities

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    L. C. Cadwallader

    2012-11-01

    This report is a compilation of some unique component repair time data and it also presents citations of more extensive reports where lists of repair times can be found. This collection of information should support analysts who seek to quantify maintainability and availability of high technology and nuclear energy production systems. While there are newer sources of repair time information, most, if not all, of the newer sources are proprietary and cannot be shared. This report offers data that, while older, is openly accessible and can serve as reasonable estimates of repair times, at least for initial studies. Some timesmore » were found for maintenance times in radiation environments, and some guidance for multiplicative factors to use to account for work in contamination areas.« less

  16. Small Engine Component Technology (SECT) study. Program report

    NASA Technical Reports Server (NTRS)

    Almodovar, E.; Exley, T.; Kaehler, H.; Schneider, W.

    1986-01-01

    The study was conducted to identify high payoff technologies for year 2000 small gas turbine applications and to provide a technology plan for guiding future research and technology efforts. A regenerative cycle turboprop engine was selected for a 19 passenger commuter aircraft application. A series of engines incorporating eight levels of advanced technologies were studied and their impact on aircraft performance was evaluated. The study indicated a potential reduction in fuel burn of 38.3 percent. At $1.00 per gallon fuel price, a potential DOC benefit of 12.5 percent would be achieved. At $2.00 per gallon, the potential DOC benefit would increase to 17.0 percent. Four advanced technologies are recommended and appropriate research and technology programs were established to reach the year 2000 goals.

  17. Key technology research of HILS based on real-time operating system

    NASA Astrophysics Data System (ADS)

    Wang, Fankai; Lu, Huiming; Liu, Che

    2018-03-01

    In order to solve the problems that the long development cycle of traditional simulation and digital simulation doesn't have the characteristics of real time, this paper designed a HILS(Hardware In the Loop Simulation) system based on the real-time operating platform xPC. This system solved the communication problems between HMI and Simulink models through the MATLAB engine interface, and realized the functions of system setting, offline simulation, model compiling and downloading, etc. Using xPC application interface and integrating the TeeChart ActiveX chart component to realize the monitoring function of real-time target application; Each functional block in the system is encapsulated in the form of DLL, and the data interaction between modules was realized by MySQL database technology. When the HILS system runs, search the address of the online xPC target by means of the Ping command, to establish the Tcp/IP communication between the two machines. The technical effectiveness of the developed system is verified through the typical power station control system.

  18. The development and technology transfer of software engineering technology at NASA. Johnson Space Center

    NASA Technical Reports Server (NTRS)

    Pitman, C. L.; Erb, D. M.; Izygon, M. E.; Fridge, E. M., III; Roush, G. B.; Braley, D. M.; Savely, R. T.

    1992-01-01

    The United State's big space projects of the next decades, such as Space Station and the Human Exploration Initiative, will need the development of many millions of lines of mission critical software. NASA-Johnson (JSC) is identifying and developing some of the Computer Aided Software Engineering (CASE) technology that NASA will need to build these future software systems. The goal is to improve the quality and the productivity of large software development projects. New trends are outlined in CASE technology and how the Software Technology Branch (STB) at JSC is endeavoring to provide some of these CASE solutions for NASA is described. Key software technology components include knowledge-based systems, software reusability, user interface technology, reengineering environments, management systems for the software development process, software cost models, repository technology, and open, integrated CASE environment frameworks. The paper presents the status and long-term expectations for CASE products. The STB's Reengineering Application Project (REAP), Advanced Software Development Workstation (ASDW) project, and software development cost model (COSTMODL) project are then discussed. Some of the general difficulties of technology transfer are introduced, and a process developed by STB for CASE technology insertion is described.

  19. A Comprehensive Algorithm for Approval of Health Technologies With, Without, or Only in Research: The Key Principles for Informing Coverage Decisions.

    PubMed

    Claxton, Karl; Palmer, Stephen; Longworth, Louise; Bojke, Laura; Griffin, Susan; Soares, Marta; Spackman, Eldon; Rothery, Claire

    The value of evidence about the performance of a technology and the value of access to a technology are central to policy decisions regarding coverage with, without, or only in research and managed entry (or risk-sharing) agreements. We aim to outline the key principles of what assessments are needed to inform "only in research" (OIR) or "approval with research" (AWR) recommendations, in addition to approval or rejection. We developed a comprehensive algorithm to inform the sequence of assessments and judgments that lead to different types of guidance: OIR, AWR, Approve, or Reject. This algorithm identifies the order in which assessments might be made, how similar guidance might be arrived at through different combinations of considerations, and when guidance might change. The key principles are whether the technology is expected to be cost-effective; whether the technology has significant irrecoverable costs; whether additional research is needed; whether research is possible with approval and whether there are opportunity costs that once committed by approval cannot be recovered; and whether there are effective price reductions. Determining expected cost-effectiveness is only a first step. In addition to AWR for technologies expected to be cost-effective and OIR for those not expected to be cost-effective, there are other important circumstances when OIR should be considered. These principles demonstrate that cost-effectiveness is a necessary but not sufficient condition for approval. Even when research is possible with approval, OIR may be appropriate when a technology is expected to be cost-effective due to significant irrecoverable costs. Copyright © 2016 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.

  20. Campus Computing, 1998. The Ninth National Survey of Desktop Computing and Information Technology in American Higher Education.

    ERIC Educational Resources Information Center

    Green, Kenneth C.

    This report presents findings of a June 1998 survey of computing officials at 1,623 two- and four-year U.S. colleges and universities concerning the use of computer technology. The survey found that computing and information technology (IT) are now core components of the campus environment and classroom experience. However, key aspects of IT…

  1. Study on Global GIS architecture and its key technologies

    NASA Astrophysics Data System (ADS)

    Cheng, Chengqi; Guan, Li; Lv, Xuefeng

    2009-09-01

    Global GIS (G2IS) is a system, which supports the huge data process and the global direct manipulation on global grid based on spheroid or ellipsoid surface. Based on global subdivision grid (GSG), Global GIS architecture is presented in this paper, taking advantage of computer cluster theory, the space-time integration technology and the virtual reality technology. Global GIS system architecture is composed of five layers, including data storage layer, data representation layer, network and cluster layer, data management layer and data application layer. Thereinto, it is designed that functions of four-level protocol framework and three-layer data management pattern of Global GIS based on organization, management and publication of spatial information in this architecture. Three kinds of core supportive technologies, which are computer cluster theory, the space-time integration technology and the virtual reality technology, and its application pattern in the Global GIS are introduced in detail. The primary ideas of Global GIS in this paper will be an important development tendency of GIS.

  2. Study on Global GIS architecture and its key technologies

    NASA Astrophysics Data System (ADS)

    Cheng, Chengqi; Guan, Li; Lv, Xuefeng

    2010-11-01

    Global GIS (G2IS) is a system, which supports the huge data process and the global direct manipulation on global grid based on spheroid or ellipsoid surface. Based on global subdivision grid (GSG), Global GIS architecture is presented in this paper, taking advantage of computer cluster theory, the space-time integration technology and the virtual reality technology. Global GIS system architecture is composed of five layers, including data storage layer, data representation layer, network and cluster layer, data management layer and data application layer. Thereinto, it is designed that functions of four-level protocol framework and three-layer data management pattern of Global GIS based on organization, management and publication of spatial information in this architecture. Three kinds of core supportive technologies, which are computer cluster theory, the space-time integration technology and the virtual reality technology, and its application pattern in the Global GIS are introduced in detail. The primary ideas of Global GIS in this paper will be an important development tendency of GIS.

  3. WRKY transcription factors: key components in abscisic acid signalling.

    PubMed

    Rushton, Deena L; Tripathi, Prateek; Rabara, Roel C; Lin, Jun; Ringler, Patricia; Boken, Ashley K; Langum, Tanner J; Smidt, Lucas; Boomsma, Darius D; Emme, Nicholas J; Chen, Xianfeng; Finer, John J; Shen, Qingxi J; Rushton, Paul J

    2012-01-01

    WRKY transcription factors (TFs) are key regulators of many plant processes, including the responses to biotic and abiotic stresses, senescence, seed dormancy and seed germination. For over 15 years, limited evidence has been available suggesting that WRKY TFs may play roles in regulating plant responses to the phytohormone abscisic acid (ABA), notably some WRKY TFs are ABA-inducible repressors of seed germination. However, the roles of WRKY TFs in other aspects of ABA signalling, and the mechanisms involved, have remained unclear. Recent significant progress in ABA research has now placed specific WRKY TFs firmly in ABA-responsive signalling pathways, where they act at multiple levels. In Arabidopsis, WRKY TFs appear to act downstream of at least two ABA receptors: the cytoplasmic PYR/PYL/RCAR-protein phosphatase 2C-ABA complex and the chloroplast envelope-located ABAR-ABA complex. In vivo and in vitro promoter-binding studies show that the target genes for WRKY TFs that are involved in ABA signalling include well-known ABA-responsive genes such as ABF2, ABF4, ABI4, ABI5, MYB2, DREB1a, DREB2a and RAB18. Additional well-characterized stress-inducible genes such as RD29A and COR47 are also found in signalling pathways downstream of WRKY TFs. These new insights also reveal that some WRKY TFs are positive regulators of ABA-mediated stomatal closure and hence drought responses. Conversely, many WRKY TFs are negative regulators of seed germination, and controlling seed germination appears a common function of a subset of WRKY TFs in flowering plants. Taken together, these new data demonstrate that WRKY TFs are key nodes in ABA-responsive signalling networks. © 2011 The Authors. Plant Biotechnology Journal © 2011 Society for Experimental Biology, Association of Applied Biologists and Blackwell Publishing Ltd.

  4. On the vulnerability of basic quantum key distribution protocols and three protocols stable to attack with 'blinding' of avalanche photodetectors

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Molotkov, S. N., E-mail: sergei.molotkov@gmail.com

    2012-05-15

    The fundamental quantum mechanics prohibitions on the measurability of quantum states allow secure key distribution between spatially remote users to be performed. Experimental and commercial implementations of quantum cryptography systems, however, use components that exist at the current technology level, in particular, one-photon avalanche photodetectors. These detectors are subject to the blinding effect. It was shown that all the known basic quantum key distribution protocols and systems based on them are vulnerable to attacks with blinding of photodetectors. In such attacks, an eavesdropper knows all the key transferred, does not produce errors at the reception side, and remains undetected. Threemore » protocols of quantum key distribution stable toward such attacks are suggested. The security of keys and detection of eavesdropping attempts are guaranteed by the internal structure of protocols themselves rather than additional technical improvements.« less

  5. Denoising of chaotic signal using independent component analysis and empirical mode decomposition with circulate translating

    NASA Astrophysics Data System (ADS)

    Wen-Bo, Wang; Xiao-Dong, Zhang; Yuchan, Chang; Xiang-Li, Wang; Zhao, Wang; Xi, Chen; Lei, Zheng

    2016-01-01

    In this paper, a new method to reduce noises within chaotic signals based on ICA (independent component analysis) and EMD (empirical mode decomposition) is proposed. The basic idea is decomposing chaotic signals and constructing multidimensional input vectors, firstly, on the base of EMD and its translation invariance. Secondly, it makes the independent component analysis on the input vectors, which means that a self adapting denoising is carried out for the intrinsic mode functions (IMFs) of chaotic signals. Finally, all IMFs compose the new denoised chaotic signal. Experiments on the Lorenz chaotic signal composed of different Gaussian noises and the monthly observed chaotic sequence on sunspots were put into practice. The results proved that the method proposed in this paper is effective in denoising of chaotic signals. Moreover, it can correct the center point in the phase space effectively, which makes it approach the real track of the chaotic attractor. Project supported by the National Science and Technology, China (Grant No. 2012BAJ15B04), the National Natural Science Foundation of China (Grant Nos. 41071270 and 61473213), the Natural Science Foundation of Hubei Province, China (Grant No. 2015CFB424), the State Key Laboratory Foundation of Satellite Ocean Environment Dynamics, China (Grant No. SOED1405), the Hubei Provincial Key Laboratory Foundation of Metallurgical Industry Process System Science, China (Grant No. Z201303), and the Hubei Key Laboratory Foundation of Transportation Internet of Things, Wuhan University of Technology, China (Grant No.2015III015-B02).

  6. Statistical Inference and Simulation with StatKey

    ERIC Educational Resources Information Center

    Quinn, Anne

    2016-01-01

    While looking for an inexpensive technology package to help students in statistics classes, the author found StatKey, a free Web-based app. Not only is StatKey useful for students' year-end projects, but it is also valuable for helping students learn fundamental content such as the central limit theorem. Using StatKey, students can engage in…

  7. Biochemical identification and biological origin of key odor components in livestock waste.

    PubMed

    Mackie, R I; Stroot, P G; Varel, V H

    1998-05-01

    Animal production results in conversion of feeds into valuable products such as meat, milk, eggs, and wool as well as into unavoidable and less desirable waste products. Intensification of animal numbers and increasing urbanization has resulted in considerable attention to odorous gases produced from animal wastes. It is clear that animal manure was, and still is, a valuable resource. However, it may be a major obstacle to future development of the animal industry if its impact on the environment is not properly controlled. Poor odor prevention and control from animal wastes is related to a lack of knowledge of the fundamental nature of odor and its production by farm animals. Odor, like noise, is a nuisance or disturbance and there is no universally accepted definition of an objectionable odor. Thus, regulation and control of odors in the environment is difficult because of the technical difficulties of defining odor limits and their measurement and evaluation. A variety of direct (sensory) and indirect (analytical instruments) methods for measuring odor intensity and determination of individual or key odor components are discussed. The biological origins of the four principal classes of odor compounds, namely branched- and straight-chain VFA, ammonia and volatile amines, indoles and phenols, and the volatile sulfur-containing compounds, are reviewed. Because more than 50% of N from animals is excreted as urea, one strategy to conserve N in waste is to inhibit the urease enzyme that converts urea to ammonia. Laboratory studies to evaluate di- and triamide compounds to control urea hydrolysis in slurries of cattle and swine wastes are presented. Finally, a brief overview of various intervention strategies is provided. Multiple combinations of nutritional management, housing systems, treatment options as well as storage and disposal of animal wastes will be required to reduce environmental pollution and provide for long-term sustainable growth.

  8. Model of Providing Assistive Technologies in Special Education Schools.

    PubMed

    Lersilp, Suchitporn; Putthinoi, Supawadee; Chakpitak, Nopasit

    2015-05-14

    Most students diagnosed with disabilities in Thai special education schools received assistive technologies, but this did not guarantee the greatest benefits. The purpose of this study was to survey the provision, use and needs of assistive technologies, as well as the perspectives of key informants regarding a model of providing them in special education schools. The participants were selected by the purposive sampling method, and they comprised 120 students with visual, physical, hearing or intellectual disabilities from four special education schools in Chiang Mai, Thailand; and 24 key informants such as parents or caregivers, teachers, school principals and school therapists. The instruments consisted of an assistive technology checklist and a semi-structured interview. Results showed that a category of assistive technologies was provided for students with disabilities, with the highest being "services", followed by "media" and then "facilities". Furthermore, mostly students with physical disabilities were provided with assistive technologies, but those with visual disabilities needed it more. Finally, the model of providing assistive technologies was composed of 5 components: Collaboration; Holistic perspective; Independent management of schools; Learning systems and a production manual for users; and Development of an assistive technology center, driven by 3 major sources such as Government and Private organizations, and Schools.

  9. Ferroelectric Based High Power Components for L-Band Accelerator Applications

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kanareykin, Alex; Jing, Chunguang; Kostin, Roman

    2018-01-16

    We are developing a new electronic device to control the power in particle accelerators. The key technology is a new nanostructured material developed by Euclid that changes its properties with an applied electric field. Both superconducting and conventional accelerating structures require fast electronic control of the input rf power. A fast controllable phase shifter would allow for example the control of the rf power delivered to multiple accelerating cavities from a single power amplifier. Nonlinear ferroelectric microwave components can control the tuning or the input power coupling for rf cavities. Applying a bias voltage across a nonlinear ferroelectric changes itsmore » permittivity. This effect can be used to cause a phase change of a propagating rf signal or change the resonant frequency of a cavity. The key is the development of a low loss highly tunable ferroelectric material.« less

  10. Implementation of continuous-variable quantum key distribution with composable and one-sided-device-independent security against coherent attacks.

    PubMed

    Gehring, Tobias; Händchen, Vitus; Duhme, Jörg; Furrer, Fabian; Franz, Torsten; Pacher, Christoph; Werner, Reinhard F; Schnabel, Roman

    2015-10-30

    Secret communication over public channels is one of the central pillars of a modern information society. Using quantum key distribution this is achieved without relying on the hardness of mathematical problems, which might be compromised by improved algorithms or by future quantum computers. State-of-the-art quantum key distribution requires composable security against coherent attacks for a finite number of distributed quantum states as well as robustness against implementation side channels. Here we present an implementation of continuous-variable quantum key distribution satisfying these requirements. Our implementation is based on the distribution of continuous-variable Einstein-Podolsky-Rosen entangled light. It is one-sided device independent, which means the security of the generated key is independent of any memoryfree attacks on the remote detector. Since continuous-variable encoding is compatible with conventional optical communication technology, our work is a step towards practical implementations of quantum key distribution with state-of-the-art security based solely on telecom components.

  11. Implementation of continuous-variable quantum key distribution with composable and one-sided-device-independent security against coherent attacks

    PubMed Central

    Gehring, Tobias; Händchen, Vitus; Duhme, Jörg; Furrer, Fabian; Franz, Torsten; Pacher, Christoph; Werner, Reinhard F.; Schnabel, Roman

    2015-01-01

    Secret communication over public channels is one of the central pillars of a modern information society. Using quantum key distribution this is achieved without relying on the hardness of mathematical problems, which might be compromised by improved algorithms or by future quantum computers. State-of-the-art quantum key distribution requires composable security against coherent attacks for a finite number of distributed quantum states as well as robustness against implementation side channels. Here we present an implementation of continuous-variable quantum key distribution satisfying these requirements. Our implementation is based on the distribution of continuous-variable Einstein–Podolsky–Rosen entangled light. It is one-sided device independent, which means the security of the generated key is independent of any memoryfree attacks on the remote detector. Since continuous-variable encoding is compatible with conventional optical communication technology, our work is a step towards practical implementations of quantum key distribution with state-of-the-art security based solely on telecom components. PMID:26514280

  12. Research and development of improved geothermal well logging techniques, tools and components (current projects, goals and status). Final report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lamers, M.D.

    One of the key needs in the advancement of geothermal energy is availability of adequate subsurface measurements to aid the reservoir engineer in the development and operation of geothermal wells. Some current projects being sponsored by the U. S. Department of Energy's Division of Geothermal Energy pertaining to the development of improved well logging techniques, tools and components are described. An attempt is made to show how these projects contribute to improvement of geothermal logging technology in forming key elements of the overall program goals.

  13. Automated reuseable components system study results

    NASA Technical Reports Server (NTRS)

    Gilroy, Kathy

    1989-01-01

    The Automated Reusable Components System (ARCS) was developed under a Phase 1 Small Business Innovative Research (SBIR) contract for the U.S. Army CECOM. The objectives of the ARCS program were: (1) to investigate issues associated with automated reuse of software components, identify alternative approaches, and select promising technologies, and (2) to develop tools that support component classification and retrieval. The approach followed was to research emerging techniques and experimental applications associated with reusable software libraries, to investigate the more mature information retrieval technologies for applicability, and to investigate the applicability of specialized technologies to improve the effectiveness of a reusable component library. Various classification schemes and retrieval techniques were identified and evaluated for potential application in an automated library system for reusable components. Strategies for library organization and management, component submittal and storage, and component search and retrieval were developed. A prototype ARCS was built to demonstrate the feasibility of automating the reuse process. The prototype was created using a subset of the classification and retrieval techniques that were investigated. The demonstration system was exercised and evaluated using reusable Ada components selected from the public domain. A requirements specification for a production-quality ARCS was also developed.

  14. A new technology perspective and engineering tools approach for large, complex and distributed mission and safety critical systems components

    NASA Technical Reports Server (NTRS)

    Carrio, Miguel A., Jr.

    1988-01-01

    Rapidly emerging technology and methodologies have out-paced the systems development processes' ability to use them effectively, if at all. At the same time, the tools used to build systems are becoming obsolescent themselves as a consequence of the same technology lag that plagues systems development. The net result is that systems development activities have not been able to take advantage of available technology and have become equally dependent on aging and ineffective computer-aided engineering tools. New methods and tools approaches are essential if the demands of non-stop and Mission and Safety Critical (MASC) components are to be met.

  15. Oleic acid is a key cytotoxic component of HAMLET-like complexes.

    PubMed

    Permyakov, Sergei E; Knyazeva, Ekaterina L; Khasanova, Leysan M; Fadeev, Roman S; Zhadan, Andrei P; Roche-Hakansson, Hazeline; Håkansson, Anders P; Akatov, Vladimir S; Permyakov, Eugene A

    2012-01-01

    HAMLET is a complex of α-lactalbumin (α-LA) with oleic acid (OA) that selectively kills tumor cells and Streptococcus pneumoniae. To assess the contribution of the proteinaceous component to cytotoxicity of HAMLET, OA complexes with proteins structurally and functionally distinct from α-LA were prepared. Similar to HAMLET, the OA complexes with bovine β-lactoglobulin (bLG) and pike parvalbumin (pPA) (bLG-OA-45 and pPA-OA-45, respectively) induced S. pneumoniae D39 cell death. The activation mechanisms of S. pneumoniae death for these complexes were analogous to those for HAMLET, and the cytotoxicity of the complexes increased with OA content in the preparations. The half-maximal inhibitory concentration for HEp-2 cells linearly decreased with rise in OA content in the preparations, and OA concentration in the preparations causing HEp-2 cell death was close to the cytotoxicity of OA alone. Hence, the cytotoxic action of these complexes against HEp-2 cells is induced mostly by OA. Thermal stabilization of bLG upon association with OA implies that cytotoxicity of bLG-OA-45 complex cannot be ascribed to molten globule-like conformation of the protein component. Overall, the proteinaceous component of HAMLET-like complexes studied is not a prerequisite for their activity; the cytotoxicity of these complexes is mostly due to the action of OA.

  16. Study on film resistivity of Energy Conversion Components for MEMS Initiating Explosive Device

    NASA Astrophysics Data System (ADS)

    Ren, Wei; Zhang, Bin; Zhao, Yulong; Chu, Enyi; Yin, Ming; Li, Hui; Wang, Kexuan

    2018-03-01

    Resistivity of Plane-film Energy Conversion Components is a key parameter to influence its resistance and explosive performance, and also it has important relations with the preparation of thin film technology, scale, structure and etc. In order to improve the design of Energy Conversion Components for MEMS Initiating Explosive Device, and reduce the design deviation of Energy Conversion Components in microscale, guarantee the design resistance and ignition performance of MEMS Initiating Explosive Device, this paper theoretically analyzed the influence factors of film resistivity in microscale, through the preparation of Al film and Ni-Cr film at different thickness with micro/nano, then obtain the film resistivity parameter of the typical metal under different thickness, and reveals the effect rule of the scale to the resistivity in microscale, at the same time we obtain the corresponding inflection point data.

  17. Higher Education Institution Branding as a Component of Country Branding in Ghana: Renaming Kwame Nkrumah University of Science and Technology

    ERIC Educational Resources Information Center

    Williams, Robert, Jr.; Osei, Collins; Omar, Maktoba

    2012-01-01

    As Higher Education Institutions (HEI) become more marketised and increasingly promotionalised, brand building gains in intensity and names become increasingly important. This conceptual paper plans to explore the application of the Renaming Process Model which depicts the key components that impact the organization brand renaming process,…

  18. The Importance of Technology Readiness in NASA Earth Venture Missions

    NASA Technical Reports Server (NTRS)

    Wells, James E.; Komar, George J.

    2009-01-01

    The first set of Venture-class investigations share the characteristic that the technology should be mature and all investigations must use mature technology that has been modeled or demonstrated in a relevant environment (Technology Readiness Level (TRL) >5). Technology Readiness Levels are a systematic metric/measurement system that supports assessments of the maturity of a particular technology and the consistent comparison of maturity between different types of technology. The TRL is used in NASA technology planning. A major step in the level of fidelity of the technology demonstration follows the completion of TRL 5. At TRL 6, a system or subsystem model or prototype must be demonstrated in a relevant environment (ground or space) representative model or prototype system or system, which would go well beyond ad hoc, "patch-cord," or discrete component level breadboarding. These TRL levels are chosen as target objectives for the Program. The challenge for offerors is that they must identify key aspects (uncertainty, multi subsystem complexity, etc) of the TRL estimate that should be properly explained in a submitted proposal. Risk minimization is a key component of the Earth Venture missions. Experiences of prior airborne missions will be shared. The discussion will address aspects of uncertainty and issues surrounding three areas of airborne earth science missions: (1) Aircraft or proposed flight platform -- Expressing the capability of the aircraft in terms of the supporting mission requirements. These issues include airplane performance characteristics (duration, range, altitude, among others) and multiship complexities. (2) Instruments -- Establishing that the instruments have been demonstrated in a relevant environment. Instruments with heritage in prior space missions meet this requirement, as do instruments tested on the ground. Evidence that the instruments have demonstrated the ability to collect data as advertised will be described. The complexity of

  19. Space Technology Mission Directorate Game Changing Development Program FY2015 Annual Program Review: Advanced Manufacturing Technology

    NASA Technical Reports Server (NTRS)

    Vickers, John; Fikes, John

    2015-01-01

    The Advance Manufacturing Technology (AMT) Project supports multiple activities within the Administration's National Manufacturing Initiative. A key component of the Initiative is the Advanced Manufacturing National Program Office (AMNPO), which includes participation from all federal agencies involved in U.S. manufacturing. In support of the AMNPO the AMT Project supports building and Growing the National Network for Manufacturing Innovation through a public-private partnership designed to help the industrial community accelerate manufacturing innovation. Integration with other projects/programs and partnerships: STMD (Space Technology Mission Directorate), HEOMD, other Centers; Industry, Academia; OGA's (e.g., DOD, DOE, DOC, USDA, NASA, NSF); Office of Science and Technology Policy, NIST Advanced Manufacturing Program Office; Generate insight within NASA and cross-agency for technology development priorities and investments. Technology Infusion Plan: PC; Potential customer infusion (TDM, HEOMD, SMD, OGA, Industry); Leverage; Collaborate with other Agencies, Industry and Academia; NASA roadmap. Initiatives include: Advanced Near Net Shape Technology Integrally Stiffened Cylinder Process Development (launch vehicles, sounding rockets); Materials Genome; Low Cost Upper Stage-Class Propulsion; Additive Construction with Mobile Emplacement (ACME); National Center for Advanced Manufacturing.

  20. Reactor Safety Gap Evaluation of Accident Tolerant Components and Severe Accident Analysis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Farmer, Mitchell T.; Bunt, R.; Corradini, M.

    The overall objective of this study was to conduct a technology gap evaluation on accident tolerant components and severe accident analysis methodologies with the goal of identifying any data and/or knowledge gaps that may exist, given the current state of light water reactor (LWR) severe accident research, and additionally augmented by insights obtained from the Fukushima accident. The ultimate benefit of this activity is that the results can be used to refine the Department of Energy’s (DOE) Reactor Safety Technology (RST) research and development (R&D) program plan to address key knowledge gaps in severe accident phenomena and analyses that affectmore » reactor safety and that are not currently being addressed by the industry or the Nuclear Regulatory Commission (NRC).« less

  1. Technology Benefit Estimator (T/BEST): User's Manual

    NASA Technical Reports Server (NTRS)

    Generazio, Edward R.; Chamis, Christos C.; Abumeri, Galib

    1994-01-01

    The Technology Benefit Estimator (T/BEST) system is a formal method to assess advanced technologies and quantify the benefit contributions for prioritization. T/BEST may be used to provide guidelines to identify and prioritize high payoff research areas, help manage research and limited resources, show the link between advanced concepts and the bottom line, i.e., accrued benefit and value, and to communicate credibly the benefits of research. The T/BEST software computer program is specifically designed to estimating benefits, and benefit sensitivities, of introducing new technologies into existing propulsion systems. Key engine cycle, structural, fluid, mission and cost analysis modules are used to provide a framework for interfacing with advanced technologies. An open-ended, modular approach is used to allow for modification and addition of both key and advanced technology modules. T/BEST has a hierarchical framework that yields varying levels of benefit estimation accuracy that are dependent on the degree of input detail available. This hierarchical feature permits rapid estimation of technology benefits even when the technology is at the conceptual stage. As knowledge of the technology details increases the accuracy of the benefit analysis increases. Included in T/BEST's framework are correlations developed from a statistical data base that is relied upon if there is insufficient information given in a particular area, e.g., fuel capacity or aircraft landing weight. Statistical predictions are not required if these data are specified in the mission requirements. The engine cycle, structural fluid, cost, noise, and emissions analyses interact with the default or user material and component libraries to yield estimates of specific global benefits: range, speed, thrust, capacity, component life, noise, emissions, specific fuel consumption, component and engine weights, pre-certification test, mission performance engine cost, direct operating cost, life cycle cost

  2. Technology Benefit Estimator (T/BEST): User's manual

    NASA Astrophysics Data System (ADS)

    Generazio, Edward R.; Chamis, Christos C.; Abumeri, Galib

    1994-12-01

    The Technology Benefit Estimator (T/BEST) system is a formal method to assess advanced technologies and quantify the benefit contributions for prioritization. T/BEST may be used to provide guidelines to identify and prioritize high payoff research areas, help manage research and limited resources, show the link between advanced concepts and the bottom line, i.e., accrued benefit and value, and to communicate credibly the benefits of research. The T/BEST software computer program is specifically designed to estimating benefits, and benefit sensitivities, of introducing new technologies into existing propulsion systems. Key engine cycle, structural, fluid, mission and cost analysis modules are used to provide a framework for interfacing with advanced technologies. An open-ended, modular approach is used to allow for modification and addition of both key and advanced technology modules. T/BEST has a hierarchical framework that yields varying levels of benefit estimation accuracy that are dependent on the degree of input detail available. This hierarchical feature permits rapid estimation of technology benefits even when the technology is at the conceptual stage. As knowledge of the technology details increases the accuracy of the benefit analysis increases. Included in T/BEST's framework are correlations developed from a statistical data base that is relied upon if there is insufficient information given in a particular area, e.g., fuel capacity or aircraft landing weight. Statistical predictions are not required if these data are specified in the mission requirements. The engine cycle, structural fluid, cost, noise, and emissions analyses interact with the default or user material and component libraries to yield estimates of specific global benefits: range, speed, thrust, capacity, component life, noise, emissions, specific fuel consumption, component and engine weights, pre-certification test, mission performance engine cost, direct operating cost, life cycle cost

  3. Continuous-variable quantum key distribution with 1 Mbps secure key rate.

    PubMed

    Huang, Duan; Lin, Dakai; Wang, Chao; Liu, Weiqi; Fang, Shuanghong; Peng, Jinye; Huang, Peng; Zeng, Guihua

    2015-06-29

    We report the first continuous-variable quantum key distribution (CVQKD) experiment to enable the creation of 1 Mbps secure key rate over 25 km standard telecom fiber in a coarse wavelength division multiplexers (CWDM) environment. The result is achieved with two major technological advances: the use of a 1 GHz shot-noise-limited homodyne detector and the implementation of a 50 MHz clock system. The excess noise due to noise photons from local oscillator and classical data channels in CWDM is controlled effectively. We note that the experimental verification of high-bit-rate CVQKD in the multiplexing environment is a significant step closer toward large-scale deployment in fiber networks.

  4. Cryptographic Key Management and Critical Risk Assessment

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Abercrombie, Robert K

    The Department of Energy Office of Electricity Delivery and Energy Reliability (DOE-OE) CyberSecurity for Energy Delivery Systems (CSEDS) industry led program (DE-FOA-0000359) entitled "Innovation for Increasing CyberSecurity for Energy Delivery Systems (12CSEDS)," awarded a contract to Sypris Electronics LLC to develop a Cryptographic Key Management System for the smart grid (Scalable Key Management Solutions for Critical Infrastructure Protection). Oak Ridge National Laboratory (ORNL) and Sypris Electronics, LLC as a result of that award entered into a CRADA (NFE-11-03562) between ORNL and Sypris Electronics, LLC. ORNL provided its Cyber Security Econometrics System (CSES) as a tool to be modified and usedmore » as a metric to address risks and vulnerabilities in the management of cryptographic keys within the Advanced Metering Infrastructure (AMI) domain of the electric sector. ORNL concentrated our analysis on the AMI domain of which the National Electric Sector Cyber security Organization Resource (NESCOR) Working Group 1 (WG1) has documented 29 failure scenarios. The computational infrastructure of this metric involves system stakeholders, security requirements, system components and security threats. To compute this metric, we estimated the stakes that each stakeholder associates with each security requirement, as well as stochastic matrices that represent the probability of a threat to cause a component failure and the probability of a component failure to cause a security requirement violation. We applied this model to estimate the security of the AMI, by leveraging the recently established National Institute of Standards and Technology Interagency Report (NISTIR) 7628 guidelines for smart grid security and the International Electrotechnical Commission (IEC) 63351, Part 9 to identify the life cycle for cryptographic key management, resulting in a vector that assigned to each stakeholder an estimate of their average loss in terms of dollars per day of

  5. Concentrating Solar Power Central Receiver Panel Component Fabrication and Testing FINAL REPORT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    McDowell, Michael W; Miner, Kris

    The objective of this project is to complete a design of an advanced concentrated solar panel and demonstrate the manufacturability of key components. Then confirm the operation of the key components under prototypic solar flux conditions. This work is an important step in reducing the levelized cost of energy (LCOE) from a central receiver solar power plant. The key technical risk to building larger power towers is building the larger receiver systems. Therefore, this proposed technology project includes the design of an advanced molten salt prototypic sub-scale receiver panel that can be utilized into a large receiver system. Then completemore » the fabrication and testing of key components of the receive design that will be used to validate the design. This project shall have a significant impact on solar thermal power plant design. Receiver panels of suitable size for utility scale plants are a key element to a solar power tower plant. Many subtle and complex manufacturing processes are involved in producing a reliable, robust receiver panel. Given the substantial size difference between receiver panels manufactured in the past and those needed for large plant designs, the manufacture and demonstration on prototype receiver panel components with representative features of a full-sized panel will be important to improving the build process for commercial success. Given the thermal flux limitations of the test facility, the panel components cannot be rendered full size. Significance changes occurred in the projects technical strategies from project initiation to the accomplishments described herein. The initial strategy was to define cost improvements for the receiver, design and build a scale prototype receiver and test, on sun, with a molten salt heat transport system. DOE had committed to constructing a molten salt heat transport loop to support receiver testing at the top of the NSTTF tower. Because of funding constraints this did not happen. A subsequent

  6. Characterization of ABS specimens produced via the 3D printing technology for drone structural components

    NASA Astrophysics Data System (ADS)

    Ferro, Carlo Giovanni; Brischetto, Salvatore; Torre, Roberto; Maggiore, Paolo

    2016-07-01

    The Fused Deposition Modelling (FDM) technology is widely used in rapid prototyping. 3D printers for home desktop applications are usually employed to make non-structural objects. When the mechanical stresses are not excessive, this technology can also be successfully employed to produce structural objects, not only in prototyping stage but also in the realization of series pieces. The innovative idea of the present work is the application of this technology, implemented in a desktop 3D printer, to the realization of components for aeronautical use, especially for unmanned aerial systems. For this purpose, the paper is devoted to the statistical study of the performance of a desktop 3D printer to understand how the process performs and which are the boundary limits of acceptance. Mechanical and geometrical properties of ABS (Acrylonitrile Butadiene Styrene) specimens, such as tensile strength and stiffness, have been evaluated. ASTM638 type specimens have been used. A capability analysis has been applied for both mechanical and dimensional performances. Statistically stable limits have been determined using experimentally collected data.

  7. Fusion technologies for Laser Inertial Fusion Energy (LIFE)

    NASA Astrophysics Data System (ADS)

    Kramer, K. J.; Latkowski, J. F.; Abbott, R. P.; Anklam, T. P.; Dunne, A. M.; El-Dasher, B. S.; Flowers, D. L.; Fluss, M. J.; Lafuente, A.; Loosmore, G. A.; Morris, K. R.; Moses, E.; Reyes, S.

    2013-11-01

    The Laser Inertial Fusion-based Energy (LIFE) engine design builds upon on going progress at the National Ignition Facility (NIF) and offers a near-term pathway to commercial fusion. Fusion technologies that are critical to success are reflected in the design of the first wall, blanket and tritium separation subsystems. The present work describes the LIFE engine-related components and technologies. LIFE utilizes a thermally robust indirect-drive target and a chamber fill gas. Coolant selection and a large chamber solid-angle coverage provide ample tritium breeding margin and high blanket gain. Target material selection eliminates the need for aggressive chamber clearing, while enabling recycling. Demonstrated tritium separation and storage technologies limit the site tritium inventory to attractive levels. These key technologies, along with the maintenance and advanced materials qualification program have been integrated into the LIFE delivery plan. This describes the development of components and subsystems, through prototyping and integration into a First Of A Kind power plant. This work performed under the auspices of the U.S. Department of Energy by Lawrence Livermore National Laboratory under Contract DE-AC52-07NA27344.

  8. Advanced Artificial Intelligence Technology Testbed

    NASA Technical Reports Server (NTRS)

    Anken, Craig S.

    1993-01-01

    The Advanced Artificial Intelligence Technology Testbed (AAITT) is a laboratory testbed for the design, analysis, integration, evaluation, and exercising of large-scale, complex, software systems, composed of both knowledge-based and conventional components. The AAITT assists its users in the following ways: configuring various problem-solving application suites; observing and measuring the behavior of these applications and the interactions between their constituent modules; gathering and analyzing statistics about the occurrence of key events; and flexibly and quickly altering the interaction of modules within the applications for further study.

  9. [Establishment of prescription research technology system in Chinese medicine secondary exploitation based on "component structure" theory].

    PubMed

    Cheng, Xu-Dong; Feng, Liang; Gu, Jun-Fei; Zhang, Ming-Hua; Jia, Xiao-Bin

    2014-11-01

    Chinese medicine prescriptions are the wisdom outcomes of traditional Chinese medicine (TCM) clinical treatment determinations which based on differentiation of symptoms and signs. Chinese medicine prescriptions are also the basis of secondary exploitation of TCM. The study on prescription helps to understand the material basis of its efficacy, pharmacological mechanism, which is an important guarantee for the modernization of traditional Chinese medicine. Currently, there is not yet dissertation n the method and technology system of basic research on the prescription of Chinese medicine. This paper focuses on how to build an effective system of prescription research technology. Based on "component structure" theory, a technology system contained four-step method that "prescription analysis, the material basis screening, the material basis of analysis and optimization and verify" was proposed. The technology system analyzes the material basis of the three levels such as Chinese medicine pieces, constituents and the compounds which could respect the overall efficacy of Chinese medicine. Ideas of prescription optimization, remodeling are introduced into the system. The technology system is the combination of the existing research and associates with new techniques and methods, which used for explore the research thought suitable for material basis research and prescription remodeling. The system provides a reference for the secondary development of traditional Chinese medicine, and industrial upgrading.

  10. Technology Literacy: A Key to the New Basic Skills.

    ERIC Educational Resources Information Center

    Brown, Richard

    The United States needs a vocational educational system that delivers, in an applied technological setting, the new basic skills that industry needs, as well as a general education system that provides creative instruction in applied math, physics, and science. To be effective, technological training should encompass, along with machine-specific…

  11. Science-Economy-Technology Concordance Matrix for Development and Implementation of Regional Smart Specializations in the Silesian Voivodeship, Poland

    PubMed Central

    Smoliński, Adam; Bondaruk, Jan; Pichlak, Magdalena; Trząski, Leszek; Uszok, Elżbieta

    2015-01-01

    The regional smart specializations include the innovative activities within a common science-economy-technology sector, which open the opportunities to gain a competitive advantage. The original procedure of science-economy-technology concordance matrix development on an example of smart specializations of the Silesian Voivodeship was presented in the paper. The procedure developed includes recognition of the research and economic components of the regional smart specialization and the connection between the economic components of the regional specialization and the technological innovation through the international patent classification. It also comprises recognition of key enabling technologies (KETs) and high technologies (of high R&D intensity) other than KET in the economic and technological dimensions of innovation as well as the high R&D intensity services in the economic dimension of innovation. The in-depth expert analyses with the application of the Delphi method were also taken into account. The methodological approach developed and the visualization method applied are both of cognitive and practical importance since they contribute significantly to the creation of efficient development policies, to the enhancement and facilitation of cross-sectoral cooperation, and to the focusing on the fields of key importance in terms of the competitive advantage of a region. PMID:26697528

  12. Science-Economy-Technology Concordance Matrix for Development and Implementation of Regional Smart Specializations in the Silesian Voivodeship, Poland.

    PubMed

    Smoliński, Adam; Bondaruk, Jan; Pichlak, Magdalena; Trząski, Leszek; Uszok, Elżbieta

    2015-01-01

    The regional smart specializations include the innovative activities within a common science-economy-technology sector, which open the opportunities to gain a competitive advantage. The original procedure of science-economy-technology concordance matrix development on an example of smart specializations of the Silesian Voivodeship was presented in the paper. The procedure developed includes recognition of the research and economic components of the regional smart specialization and the connection between the economic components of the regional specialization and the technological innovation through the international patent classification. It also comprises recognition of key enabling technologies (KETs) and high technologies (of high R&D intensity) other than KET in the economic and technological dimensions of innovation as well as the high R&D intensity services in the economic dimension of innovation. The in-depth expert analyses with the application of the Delphi method were also taken into account. The methodological approach developed and the visualization method applied are both of cognitive and practical importance since they contribute significantly to the creation of efficient development policies, to the enhancement and facilitation of cross-sectoral cooperation, and to the focusing on the fields of key importance in terms of the competitive advantage of a region.

  13. Scalable Power-Component Models for Concept Testing

    DTIC Science & Technology

    2011-08-17

    Scalable Power-Component Models for Concept Testing, Mazzola, et al . UNCLASSIFIED: Dist A. Approved for public release 2011 NDIA GROUND VEHICLE...Power-Component Models for Concept Testing, Mazzola, et al . UNCLASSIFIED: Dist A. Approved for public release Page 2 of 8 technology that has yet...Technology Symposium (GVSETS) Scalable Power-Component Models for Concept Testing, Mazzola, et al . UNCLASSIFIED: Dist A. Approved for public release

  14. Enery Efficient Press and Sinter of Titanium Powder for Low-Cost Components in Vehicle Applications

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Thomas Zwitter; Phillip Nash; Xiaoyan Xu

    2011-03-31

    This is the final technical report for the Department of Energy NETL project NT01931 Energy Efficient Press and Sinter of Titanium Powder for Low-Cost Components in Vehicle Applications. Titanium has been identified as one of the key materials with the required strength that can reduce the weight of automotive components and thereby reduce fuel consumption. Working with newly developed sources of titanium powder, Webster-Hoff will develop the processing technology to manufacture low cost vehicle components using the single press/single sinter techniques developed for iron based powder metallurgy today. Working with an automotive or truck manufacturer, Webster-Hoff will demonstrate the feasibilitymore » of manufacturing a press and sinter titanium component for a vehicle application. The project objective is two-fold, to develop the technology for manufacturing press and sinter titanium components, and to demonstrate the feasibility of producing a titanium component for a vehicle application. The lowest cost method for converting metal powder into a net shape part is the Powder Metallurgy Press and Sinter Process. The method involves compaction of the metal powder in a tool (usually a die and punches, upper and lower) at a high pressure (up to 60 TSI or 827 MPa) to form a green compact with the net shape of the final component. The powder in the green compact is held together by the compression bonds between the powder particles. The sinter process then converts the green compact to a metallurgically bonded net shape part through the process of solid state diffusion. The goal of this project is to expand the understanding and application of press and sinter technology to Titanium Powder applications, developing techniques to manufacture net shape Titanium components via the press and sinter process. In addition, working with a vehicle manufacturer, demonstrate the feasibility of producing a titanium component for a vehicle. This is not a research program, but

  15. Capacity building in water demand management as a key component for attaining millennium development goals

    NASA Astrophysics Data System (ADS)

    Gumbo, Bekithemba; Forster, Laura; Arntzen, Jaap

    Successful water demand management (WDM) implementation as a component of integrated water resource management (IWRM) can play a significant role in the alleviation of poverty through more efficient use of available water resources. The urban population in Southern African cities is characterised by so-called ‘water poor’ communities who typically expend a high percentage of their household income on poor quality water. Usually they have no access to an affordable alternative source. Although WDM as a component of IWRM is not a panacea for poverty, it can help alleviate poverty by facilitating water services management by municipal water supply agencies (MWSAs) in the region. WDM is a key strategy for achieving the millennium development goals (MDGs) and, as such, should be given due attention in the preparation of national IWRM and water efficiency plans. Various studies in the Southern African region have indicated that capacity building is necessary for nations to develop IWRM and water-use efficiency plans to meet the targets set out in the MDGs. WDM education and training of water professionals and end-users is particularly important in developing countries, which are resource and information-access poor. In response to these findings, The World Conservation Union (IUCN) and its consulting partners, the Training and Instructional Design Academy of South Africa (TIDASA), and Centre for Applied Research (CAR) designed, developed and presented a pilot WDM Guideline Training Module for MWSAs as part of Phase II of IUCN’s Southern Africa regional WDM project. Pilot training was conducted in July 2004 in Lusaka, Zambia for a group of 36 participants involved in municipal water supply from nine Southern African countries. This paper looks at the links between building the capacity of professionals, operational staff and other role-players in the municipal water supply chain to implement WDM as part of broader IWRM strategies, and the subsequent potential for

  16. Wicked problems in space technology development at NASA

    NASA Astrophysics Data System (ADS)

    Balint, Tibor S.; Stevens, John

    2016-01-01

    Technological innovation is key to enable future space exploration missions at NASA. Technology development, however, is not only driven by performance and resource considerations, but also by a broad range of directly or loosely interconnected factors. These include, among others, strategy, policy and politics at various levels, tactics and programmatics, interactions between stakeholders, resource requirements, performance goals from component to system level, mission infusion targets, portfolio execution and tracking, and technology push or mission pull. Furthermore, at NASA, these influences occur on varying timescales and at diverse geographic locations. Such a complex and interconnected system could impede space technology innovation in this examined segment of the government environment. Hence, understanding the process through NASA's Planning, Programming, Budget and Execution cycle could benefit strategic thinking, planning and execution. Insights could be gained through suitable models, for example assessing the key drivers against the framework of Wicked Problems. This paper discusses NASA specific space technology innovation and innovation barriers in the government environment through the characteristics of Wicked Problems; that is, they do not have right or wrong solutions, only improved outcomes that can be reached through authoritative, competitive, or collaborative means. We will also augment the Wicked Problems model to account for the temporally and spatially coupled, and cyclical nature of this NASA specific case, and propose how appropriate models could improve understanding of the key influencing factors. In turn, such understanding may subsequently lead to reducing innovation barriers, and stimulating technology innovation at NASA. Furthermore, our approach can be adopted for other government-directed environments to gain insights into their structures, hierarchies, operational flow, and interconnections to facilitate circular dialogs towards

  17. Foam core shield (FCS) systems : a new dual - purpose technology for shielding against meteoroid strike damage and for thermal control of spacecrafts/satellite components

    NASA Technical Reports Server (NTRS)

    Adams, Marc A.; Zwissler, James G.; Hayes, Charles; Fabensky, Beth; Cornelison, Charles; Alexander, Lesley; Bishop, Karen

    2005-01-01

    A new technology is being developed that can protect spacecraft and satellite components against damage from meteoroid strikes and control the thermal environment of the protected components. This technology, called Foam Core Shield (FCS) systems, has the potential to replace the multi-layer insulation blankets (MLI) that have been used on spacecraft for decades. In order to be an attractive candidate for replacing MLI, FCS systems should not only provide superior protection against meteoroid strikes but also provide an equal or superior ability to control the temperature of the protected component. Properly designed FCS systems can provide these principal functions, meteoroid strike protection and thermal control, with lower system mass and a smaller system envelope than ML.

  18. NREL Makes Key Appointments

    Science.gov Websites

    Makes Key Appointments Staffing for Distributed Energy and Tech Management Announced For more information contact: Gary Schmitz, 303-275-4050 email: Gary Schmitz Golden, Colo., Feb. 28, 2001 - Two reorganized Planning and Technology Management Division. Anthony Schaffhauser has been selected to become

  19. [Research on inorganic explosive and its principal component with laser-induced breakdown spectroscopy].

    PubMed

    Zhao, Hua; Wang, Qian-qian; Liu, Kai; Ge, Cong-hui

    2012-03-01

    Laser-induced breakdown spectroscopy is a technology that can be used for high-speed, real time, multi-component, online, remote detection, and it has considerable superiority in explosives detection. In the present experiment, using 1 064 nm Q-switch laser beam as the resource, the authors investigated a common inorganic explosive (black powder) and one of its key components (KNO3), while choosing NaNO3 as the reference. We obtained the LIBS spectroscopy of these three samples in two surrounding atmospheres (air and Ar gas) at different time delay. And we analysed the change in line intensity ratio of N, O along with the increase in time delay, and found that the maximum of the value of O/N is obtained at time delay 596 ns.

  20. Identifying key components for an effective case report poster: an observational study.

    PubMed

    Willett, Lisa L; Paranjape, Anuradha; Estrada, Carlos

    2009-03-01

    Residents demonstrate scholarly activity by presenting posters at academic meetings. Although recommendations from national organizations are available, evidence identifying which components are most important is not. To develop and test an evaluation tool to measure the quality of case report posters and identify the specific components most in need of improvement. Faculty evaluators reviewed case report posters and provided on-site feedback to presenters at poster sessions of four annual academic general internal medicine meetings. A newly developed ten-item evaluation form measured poster quality for specific components of content, discussion, and format (5-point Likert scale, 1 = lowest, 5 = highest). Evaluation tool performance, including Cronbach alpha and inter-rater reliability, overall poster scores, differences across meetings and evaluators and specific components of the posters most in need of improvement. Forty-five evaluators from 20 medical institutions reviewed 347 posters. Cronbach's alpha of the evaluation form was 0.84 and inter-rater reliability, Spearman's rho 0.49 (p < 0.001). The median score was 4.1 (Q1 -Q3, 3.7-4.6)(Q1 = 25th, Q3 = 75th percentile). The national meeting median score was higher than the regional meetings (4.4 vs, 4.0, P < 0.001). We found no difference in faculty scores. The following areas were identified as most needing improvement: clearly state learning objectives, tie conclusions to learning objectives, and use appropriate amount of words. Our evaluation tool provides empirical data to guide trainees as they prepare posters for presentation which may improve poster quality and enhance their scholarly productivity.

  1. Study on the key technology of grain logistics tracking system

    NASA Astrophysics Data System (ADS)

    Zhen, Tong; Ge, Hongyi; Jiang, Yuying; Che, Yi

    2010-07-01

    In recent year, with the rapid development of GIS technology, more and more programming problems depend on the GIS technology and professional model system. The solution of auxiliary programming problem by using GIS technology, which has become very popular. GIS is an important tool and technology, that captures, stores, analyzes, manages, and presents data that are linked to location. A grain logistics distribution system based on GIS is established, which provides a visualization scheme during the process of grain circulation and supports users making decision and analyzing for grain logistics enterprise.

  2. Does Technology Integration "Work" when Key Barriers Are Removed?

    ERIC Educational Resources Information Center

    Lowther, Deborah L.; Inan, Fethi A.; Strahl, J. Daniel; Ross, Steven M.

    2008-01-01

    The effectiveness of Tennessee EdTech Launch (TnETL), a statewide technology program designed to meet the No Child Left Behind (NCLB) mandate, was investigated in this matched treatment-control quasi-experimental study. The goal of the program was to provide full-time, on-site technology coaches to prepare teachers to create lessons that engage…

  3. Trends, Opportunities, and Challenges for Tall Wind Turbine and Tower Technologies

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lantz, Eric; Roberts, Owen; Dykes, Katherine

    This presentation summarizes recent analysis focused on characterizing the opportunity for Tall Wind technologies generally and for tall tower technologies specifically. It seeks to illuminate and explain the concept of Tall Wind, its impact on the wind industry to date, and the potential value of Tall Wind in the future. It also explores the conditions and locations under which the impacts of Tall Wind offer the most significant potential to increase wind technology performance. In addition, it seeks to examine the status of tall tower technology as a key sub-component of Tall Wind, focusing on the potential for continued innovationmore » in tubular steel wind turbine towers and the status and potential for a select set of alternative tall tower technologies.« less

  4. An extension of fracture mechanics/technology to larger and smaller cracks/defects.

    PubMed

    Abé, Hiroyuki

    2009-01-01

    Fracture mechanics/technology is a key science and technology for the design and integrity assessment of the engineering structures. However, the conventional fracture mechanics has mostly targeted a limited size of cracks/defects, say of from several hundred microns to several tens of centimeters. The author and his group has tried to extend that limited size and establish a new version of fracture technology for very large cracks used in geothermal energy extraction and for very small cracks/defects or damage often appearing in the combination of mechanical and electronic components of engineering structures. Those new versions are reviewed in this paper.

  5. Overall Key Performance Indicator to Optimizing Operation of High-Pressure Homogenizers for a Reliable Quantification of Intracellular Components in Pichia pastoris.

    PubMed

    Garcia-Ortega, Xavier; Reyes, Cecilia; Montesinos, José Luis; Valero, Francisco

    2015-01-01

    The most commonly used cell disruption procedures may present lack of reproducibility, which introduces significant errors in the quantification of intracellular components. In this work, an approach consisting in the definition of an overall key performance indicator (KPI) was implemented for a lab scale high-pressure homogenizer (HPH) in order to determine the disruption settings that allow the reliable quantification of a wide sort of intracellular components. This innovative KPI was based on the combination of three independent reporting indicators: decrease of absorbance, release of total protein, and release of alkaline phosphatase activity. The yeast Pichia pastoris growing on methanol was selected as model microorganism due to it presents an important widening of the cell wall needing more severe methods and operating conditions than Escherichia coli and Saccharomyces cerevisiae. From the outcome of the reporting indicators, the cell disruption efficiency achieved using HPH was about fourfold higher than other lab standard cell disruption methodologies, such bead milling cell permeabilization. This approach was also applied to a pilot plant scale HPH validating the methodology in a scale-up of the disruption process. This innovative non-complex approach developed to evaluate the efficacy of a disruption procedure or equipment can be easily applied to optimize the most common disruption processes, in order to reach not only reliable quantification but also recovery of intracellular components from cell factories of interest.

  6. Overall Key Performance Indicator to Optimizing Operation of High-Pressure Homogenizers for a Reliable Quantification of Intracellular Components in Pichia pastoris

    PubMed Central

    Garcia-Ortega, Xavier; Reyes, Cecilia; Montesinos, José Luis; Valero, Francisco

    2015-01-01

    The most commonly used cell disruption procedures may present lack of reproducibility, which introduces significant errors in the quantification of intracellular components. In this work, an approach consisting in the definition of an overall key performance indicator (KPI) was implemented for a lab scale high-pressure homogenizer (HPH) in order to determine the disruption settings that allow the reliable quantification of a wide sort of intracellular components. This innovative KPI was based on the combination of three independent reporting indicators: decrease of absorbance, release of total protein, and release of alkaline phosphatase activity. The yeast Pichia pastoris growing on methanol was selected as model microorganism due to it presents an important widening of the cell wall needing more severe methods and operating conditions than Escherichia coli and Saccharomyces cerevisiae. From the outcome of the reporting indicators, the cell disruption efficiency achieved using HPH was about fourfold higher than other lab standard cell disruption methodologies, such bead milling cell permeabilization. This approach was also applied to a pilot plant scale HPH validating the methodology in a scale-up of the disruption process. This innovative non-complex approach developed to evaluate the efficacy of a disruption procedure or equipment can be easily applied to optimize the most common disruption processes, in order to reach not only reliable quantification but also recovery of intracellular components from cell factories of interest. PMID:26284241

  7. Formation of a New Entity to Support Effective Use of Technology in Medical Education: The Student Technology Committee.

    PubMed

    Shenson, Jared Andrew; Adams, Ryan Christopher; Ahmed, S Toufeeq; Spickard, Anderson

    2015-09-17

    As technology in medical education expands from teaching tool to crucial component of curricular programming, new demands arise to innovate and optimize educational technology. While the expectations of today's digital native students are significant, their experience and unique insights breed new opportunities to involve them as stakeholders in tackling educational technology challenges. The objective of this paper is to present our experience with a novel medical student-led and faculty-supported technology committee that was developed at Vanderbilt University School of Medicine to harness students' valuable input in a comprehensive fashion. Key lessons learned through the initial successes and challenges of implementing our model are also discussed. A committee was established with cooperation of school administration, a faculty advisor with experience launching educational technologies, and a group of students passionate about this domain. Committee membership is sustained through annual selective recruitment of interested students. The committee serves 4 key functions: acting as liaisons between students and administration; advising development of institutional educational technologies; developing, piloting, and assessing new student-led educational technologies; and promoting biomedical and educational informatics within the school community. Participating students develop personally and professionally, contribute to program implementation, and extend the field's understanding by pursuing research initiatives. The institution benefits from rapid improvements to educational technologies that meet students' needs and enhance learning opportunities. Students and the institution also gain from fostering a campus culture of awareness and innovation in informatics and medical education. The committee's success hinges on member composition, school leadership buy-in, active involvement in institutional activities, and support for committee initiatives. Students

  8. NASA X-34 Technology in Motion

    NASA Technical Reports Server (NTRS)

    Beech, Geoffrey; Chandler, Kristie

    1997-01-01

    The X-34 technology development program is a joint industry/government project to develop, test, and operate a small, fully-reusable hypersonic flight vehicle. The objective is to demonstrate key technologies and operating concepts applicable to future reusable launch vehicles. Integrated in the vehicle are various systems to assure successful completion of mission objectives, including the Main Propulsion System (MPS). NASA-Marshall Space Flight Center (MSFC) is responsible for developing the X-34's MPS including the design and complete build package for the propulsion system components. The X-34 will be powered by the Fastrac Engine, which is currently in design and development at NASA-MSFC. Fastrac is a single-stage main engine, which burns a mixture of liquid oxygen (LOX) and kerosene(RP-1). The interface between the MPS and Fastrac engine are critical for proper system operation and technologies applicable to future reusable launch vehicles. Deneb's IGRIP software package with the Dynamic analysis option provided a key tool for conducting studies critical to this interface as well as a mechanism to drive the design of the LOX and RP-1 feedlines. Kinematic models were created for the Fastrac Engine and the feedlines for various design concepts. Based on the kinematic simulation within Envision, design and joint limits were verified and system interference controlled. It was also critical to the program to evaluate the effect of dynamic loads visually, providing a verification tool for dynamic analysis and in some cases uncovering areas that had not been considered. Deneb's software put the X-34 technology in motion and has been a key factor in facilitating the strenuous design schedule.

  9. Identifying Key Components for an Effective Case Report Poster: An Observational Study

    PubMed Central

    Paranjape, Anuradha; Estrada, Carlos

    2008-01-01

    BACKGROUND Residents demonstrate scholarly activity by presenting posters at academic meetings. Although recommendations from national organizations are available, evidence identifying which components are most important is not. OBJECTIVE To develop and test an evaluation tool to measure the quality of case report posters and identify the specific components most in need of improvement. DESIGN Faculty evaluators reviewed case report posters and provided on-site feedback to presenters at poster sessions of four annual academic general internal medicine meetings. A newly developed ten-item evaluation form measured poster quality for specific components of content, discussion, and format (5-point Likert scale, 1 = lowest, 5 = highest). Main outcome measure(s): Evaluation tool performance, including Cronbach alpha and inter-rater reliability, overall poster scores, differences across meetings and evaluators and specific components of the posters most in need of improvement. RESULTS Forty-five evaluators from 20 medical institutions reviewed 347 posters. Cronbach’s alpha of the evaluation form was 0.84 and inter-rater reliability, Spearman’s rho 0.49 ( < 0.001). The median score was 4.1 (Q1 -Q3, 3.7-4.6)(Q1 = 25th, Q3 = 75th percentile). The national meeting median score was higher than the regional meetings (4.4 vs, 4.0,  < 0.001). We found no difference in faculty scores. The following areas were identified as most needing improvement: clearly state learning objectives, tie conclusions to learning objectives, and use appropriate amount of words. CONCLUSIONS Our evaluation tool provides empirical data to guide trainees as they prepare posters for presentation which may improve poster quality and enhance their scholarly productivity. PMID:19089510

  10. Key Reconciliation for High Performance Quantum Key Distribution

    PubMed Central

    Martinez-Mateo, Jesus; Elkouss, David; Martin, Vicente

    2013-01-01

    Quantum Key Distribution is carving its place among the tools used to secure communications. While a difficult technology, it enjoys benefits that set it apart from the rest, the most prominent is its provable security based on the laws of physics. QKD requires not only the mastering of signals at the quantum level, but also a classical processing to extract a secret-key from them. This postprocessing has been customarily studied in terms of the efficiency, a figure of merit that offers a biased view of the performance of real devices. Here we argue that it is the throughput the significant magnitude in practical QKD, specially in the case of high speed devices, where the differences are more marked, and give some examples contrasting the usual postprocessing schemes with new ones from modern coding theory. A good understanding of its implications is very important for the design of modern QKD devices. PMID:23546440

  11. Advanced solar dynamic space power systems perspectives, requirements and technology needs

    NASA Technical Reports Server (NTRS)

    Dustin, M. O.; Savino, J. M.; Lacy, D. E.; Migra, R. P.; Juhasz, A. J.; Coles, C. E.

    1986-01-01

    Projected NASA, Civil, Commercial, and Military missions will require space power systems of increased versatility and power levels. The Advanced Solar Dynamic (ASD) Power systems offer the potential for efficient, lightweight, survivable, relatively compact, long-lived space power systems applicable to a wide range of power levels (3 to 300 kWe), and a wide variety of orbits. The successful development of these systems could satisfy the power needs for a wide variety of these projected missions. Thus, the NASA Lewis Research Center has embarked upon an aggressive ASD reserach project under the direction of NASA's Office of Aeronautics and Space Technology (DAST). The project is being implemented through a combination of in-house and contracted efforts. Key elements of this project are missions analysis to determine the power systems requirements, systems analysis to identify the most attractive ASD power systems to meet these requirements, and to guide the technology development efforts, and technology development of key components.

  12. A review of fracture mechanics life technology

    NASA Technical Reports Server (NTRS)

    Besuner, P. M.; Harris, D. O.; Thomas, J. M.

    1986-01-01

    Lifetime prediction technology for structural components subjected to cyclic loads is examined. The central objectives of the project are: (1) to report the current state of the art, and (2) recommend future development of fracture mechanics-based analytical tools for modeling subcritical fatigue crack growth in structures. Of special interest is the ability to apply these tools to practical engineering problems and the developmental steps necessary to bring vital technologies to this stage. The authors conducted a survey of published literature and numerous discussions with experts in the field of fracture mechanics life technology. One of the key points made is that fracture mechanics analyses of crack growth often involve consideration of fatigue and fracture under extreme conditions. Therefore, inaccuracies in predicting component lifetime will be dominated by inaccuracies in environment and fatigue crack growth relations, stress intensity factor solutions, and methods used to model given loads and stresses. Suggestions made for reducing these inaccuracies include development of improved models of subcritical crack growth, research efforts aimed at better characterizing residual and assembly stresses that can be introduced during fabrication, and more widespread and uniform use of the best existing methods.

  13. A review of fracture mechanics life technology

    NASA Technical Reports Server (NTRS)

    Thomas, J. M.; Besuner, P. M.; Harris, D. O.

    1985-01-01

    Current lifetime prediction technology for structural components subjected to cyclic loads was reviewed. The central objectives of the project were to report the current state of and recommend future development of fracture mechanics-based analytical tools for modeling and forecasting subcritical fatigue crack growth in structures. Of special interest to NASA was the ability to apply these tools to practical engineering problems and the developmental steps necessary to bring vital technologies to this stage. A survey of published literature and numerous discussions with experts in the field of fracture mechanics life technology were conducted. One of the key points made is that fracture mechanics analyses of crack growth often involve consideration of fatigue and fracture under extreme conditions. Therefore, inaccuracies in predicting component lifetime will be dominated by inaccuracies in environment and fatigue crack growth relations, stress intensity factor solutions, and methods used to model given loads and stresses. Suggestions made for reducing these inaccuracies include: development of improved models of subcritical crack growth, research efforts aimed at better characterizing residual and assembly stresses that can be introduced during fabrication, and more widespread and uniform use of the best existing methods.

  14. Analysis of key technologies in geomagnetic navigation

    NASA Astrophysics Data System (ADS)

    Zhang, Xiaoming; Zhao, Yan

    2008-10-01

    Because of the costly price and the error accumulation of high precise Inertial Navigation Systems (INS) and the vulnerability of Global Navigation Satellite Systems (GNSS), the geomagnetic navigation technology, a passive autonomous navigation method, is paid attention again. Geomagnetic field is a natural spatial physical field, and is a function of position and time in near earth space. The navigation technology based on geomagnetic field is researched in a wide range of commercial and military applications. This paper presents the main features and the state-of-the-art of Geomagnetic Navigation System (GMNS). Geomagnetic field models and reference maps are described. Obtaining, modeling and updating accurate Anomaly Magnetic Field information is an important step for high precision geomagnetic navigation. In addition, the errors of geomagnetic measurement using strapdown magnetometers are analyzed. The precise geomagnetic data is obtained by means of magnetometer calibration and vehicle magnetic field compensation. According to the measurement data and reference map or model of geomagnetic field, the vehicle's position and attitude can be obtained using matching algorithm or state-estimating method. The tendency of geomagnetic navigation in near future is introduced at the end of this paper.

  15. A host basal transcription factor is a key component for infection of rice by TALE-carrying bacteria.

    PubMed

    Yuan, Meng; Ke, Yinggen; Huang, Renyan; Ma, Ling; Yang, Zeyu; Chu, Zhaohui; Xiao, Jinghua; Li, Xianghua; Wang, Shiping

    2016-07-29

    Transcription activator-like effectors (TALEs) are sequence-specific DNA binding proteins found in a range of plant pathogenic bacteria, where they play important roles in host-pathogen interactions. However, it has been unclear how TALEs, after they have been injected into the host cells, activate transcription of host genes required for infection success. Here, we show that the basal transcription factor IIA gamma subunit TFIIAγ5 from rice is a key component for infection by the TALE-carrying bacterium Xanthomonas oryzae pv. oryzae, the causal agent for bacterial blight. Direct interaction of several TALEs with TFIIAγ5 is required for activation of disease susceptibility genes. Conversely, reduced expression of the TFIIAγ5 host gene limits the induction of susceptibility genes and thus decreases bacterial blight symptoms. Suppression or mutation of TFIIAγ5 can also reduce bacterial streak, another devastating disease of rice caused by TALE-carrying X. oryzae pv. oryzicola. These results have important implications for formulating a widely applicable strategy with which to improve resistance of plants to TALE-carrying pathogens.

  16. Technology transfer: The key to successful space engineering education

    NASA Astrophysics Data System (ADS)

    Fletcher, L. S.; Page, R. H.

    The 1990s are the threshold of the space revolution for the next century. This space revolution was initiated by space pioneers like Tsiolkovsky, Goddard, and Oberth, who contributed a great deal to the evolution of space exploration, and more importantly, to space education. Recently, space engineering education programs for all ages have been advocated around the world, especially in Asia and Europe, as well as the U.S.A. and the Soviet Union. And yet, although space related technologies are developing rapidly, these technologies are not being incorporated successfully into space education programs. Timely technology transfer is essential to assure the continued education of professionals. This paper reviews the evolution of space engineering education and identifies a number of initiatives which could strengthen space engineering education for the next century.

  17. Three two-week enhancement institutes: Design and implementation of the technology and telecomputing component

    NASA Technical Reports Server (NTRS)

    Hale, L. Vincent

    1995-01-01

    The Teacher Enhancement Institute (TEI), under the direction of the Center Education Programs Officer offered three two-week workshops to 58 elementary and middle school teachers in science, math, and technology using the Problem Based Learning Model. The 1995 program was designed with input from evaluations and recommendations from previous TEI participants and faculty. The TEI focused on Aviation and Aeronautics as the unifying theme. Four specific objectives were developed. After completing the requirements for the TEI, the participants should be able to: (1) Increase their content knowledge, particularly in aeronautics, science, math, and technology; (2) Design and implement lessons that use scientific inquiry through Problem Based Learning; (3) Demonstrate knowledge of instructional technologies, their uses, and applications to curricula; and (4) Disseminate to their school communities the information acquired through the TEI. Thirty percent of the program was devoted to the effective use of computer technology. SpaceLink, the NASA telecomputing service for educators, was the primary tool used in the technology component of the institute. The training focused on the use of SpaceLink and its many educational services, and Internet tools because of its universal, nongraphical link to any computer plafform the participant may use at his or her school or home. All participants were given Educator Accounts to facilitate the use of E-mail, and access to the Internet and the World Wide Web using their SpaceLink accounts. Classroom demonstrations used videotaped guides and handouts to support concepts presented followed by intensive hands-on activities. Each participant was assigned to an individual Power Mac networked workstation and introduced to the state of the art, graphical, Word Wide Web with the Netscape browser. The methodology proved very effective in reaching the program's goals for technology integration by having the participants learn to use the computer

  18. Making Ceramic Components For Advanced Aircraft Engines

    NASA Technical Reports Server (NTRS)

    Franklin, J. E.; Ezis, A.

    1994-01-01

    Lightweight, oxidation-resistant silicon nitride components containing intricate internal cooling and hydraulic passages and capable of withstanding high operating temperatures made by ceramic-platelet technology. Used to fabricate silicon nitride test articles of two types: components of methane-cooled regenerator for air turbo ramjet engine and components of bipropellant injector for rocket engine. Procedures for development of more complex and intricate components established. Technology has commercial utility in automotive, aircraft, and environmental industries for manufacture of high-temperature components for use in regeneration of fuels, treatment of emissions, high-temperature combustion devices, and application in which other high-temperature and/or lightweight components needed. Potential use in fabrication of combustors and high-temperature acoustic panels for suppression of noise in future high-speed aircraft.

  19. There’s an App for That: A Guide for Healthcare Practitioners and Researchers on Smartphone Technology

    PubMed Central

    Trevena, Lyndal

    2015-01-01

    Smartphone technology is nascent compared to other technologies; however, it has shown an unprecedented uptake amongst lay consumers and professionals. This article presents the history, components, and key features of smartphones, as well as their related concepts and how they work, and it also delineates the process of smartphone applications (apps) development and publishing in the app stores. It also describes and discusses smartphone technology utilisation for health consumers, healthcare professionals, and health researchers, as well as the regulations of health-related apps. PMID:26392848

  20. A Novel Multiple-Access Correlation-Delay-Shift-Keying

    NASA Astrophysics Data System (ADS)

    Duan, J. Y.; Jiang, G. P.; Yang, H.

    In Correlation-Delay-Shift-Keying (CDSK), the reference signal and the information-bearing signal are added together during a certain time delay. Because the reference signal is not strictly orthogonal to the information-bearing signal, the cross-correlation between the adjacent chaotic signal (Intra-signal Interference, ISI) will be introduced into the demodulation at the receiver. Therefore, the Bit-Error Ratio (BER) of CDSK is higher than that of Differential-Chaos-Shift-Keying (DCSK). To avoid the ISI component and enhance the BER performance of CDSK in multiuser scenario, Multiple-Access CDSK with No Intra-signal Interference (MA-CDSK-NII) is proposed. By constructing the repeated chaotic generator and applying the Walsh code sequence to modulate the reference signal, in MA-CDSK-NII, the ISI component will be eliminated during the demodulation. Gaussian approximation method is adopted here to obtain the exact performance analysis of MA-CDSK-NII over additive white Gaussian noise (AWGN) channel and Rayleigh multipath fading channels. Results show that, due to no ISI component and lower transmitting power, the BER performance of MA-CDSK-NII can be better than that of multiple-access CDSK and Code-Shifted Differential-Chaos-Shift-Keying (CS-DCSK).

  1. A feasibility work on the applications of MRE to automotive components

    NASA Astrophysics Data System (ADS)

    Kim, S. H.; Park, Y. J.; Cha, A. R.; Kim, G. W.; Bang, J. H.; Lim, C. S.; Choi, S. B.

    2018-03-01

    A feasibility work on the application of magneto-rheological elastomers (MREs) to automotive components, such as engine mounts is presented. While vehicle components require the high resonance frequency in terms of ride quality and handling, it is required to have the low resonance frequency to isolate the incoming vibration. With the conventional automotive technologies, it is challenging to combine these two conflicting performance trade-offs, ride quality including handling, and NVH (noise, vibration and harshness). Over the last decades, MREs, one of the new emerging smart materials, have been widely used to resolve this technical limitation. For example, an advanced engine mount was developed by using MRE to isolate the vibration transmitting from engines. In this paper, we will focus on rear cross member bushes, which is a key component for isolating the vibration from the road, and demonstrate their improved performance by utilizing MRE. The resonance frequency shift induced by the stiffness change of MRE will be presented through the frequency response functions estimated by simulation result.

  2. Prognostics and Health Management in Nuclear Power Plants: A Review of Technologies and Applications

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Coble, Jamie B.; Ramuhalli, Pradeep; Bond, Leonard J.

    This report reviews the current state of the art of prognostics and health management (PHM) for nuclear power systems and related technology currently applied in field or under development in other technological application areas, as well as key research needs and technical gaps for increased use of PHM in nuclear power systems. The historical approach to monitoring and maintenance in nuclear power plants (NPPs), including the Maintenance Rule for active components and Aging Management Plans for passive components, are reviewed. An outline is given for the technical and economic challenges that make PHM attractive for both legacy plants through Lightmore » Water Reactor Sustainability (LWRS) and new plant designs. There is a general introduction to PHM systems for monitoring, fault detection and diagnostics, and prognostics in other, non-nuclear fields. The state of the art for health monitoring in nuclear power systems is reviewed. A discussion of related technologies that support the application of PHM systems in NPPs, including digital instrumentation and control systems, wired and wireless sensor technology, and PHM software architectures is provided. Appropriate codes and standards for PHM are discussed, along with a description of the ongoing work in developing additional necessary standards. Finally, an outline of key research needs and opportunities that must be addressed in order to support the application of PHM in legacy and new NPPs is presented.« less

  3. An extension of fracture mechanics/technology to larger and smaller cracks/defects

    PubMed Central

    Abé, Hiroyuki

    2009-01-01

    Fracture mechanics/technology is a key science and technology for the design and integrity assessment of the engineering structures. However, the conventional fracture mechanics has mostly targeted a limited size of cracks/defects, say of from several hundred microns to several tens of centimeters. The author and his group has tried to extend that limited size and establish a new version of fracture technology for very large cracks used in geothermal energy extraction and for very small cracks/defects or damage often appearing in the combination of mechanical and electronic components of engineering structures. Those new versions are reviewed in this paper. PMID:19907123

  4. SENER molten salt tower technology. Ouarzazate NOOR III case

    NASA Astrophysics Data System (ADS)

    Relloso, Sergio; Gutiérrez, Yolanda

    2017-06-01

    NOOR III 150 MWe project is the evolution of Gemasolar (19.9 MWe) to large scale Molten Salt Tower plants. With more than 5 years of operational experience, Gemasolar lessons learned have been the starting point for the optimization of this technology, considered the leader of potential cost reduction in CSP. In addition, prototypes of plant key components (heliostat and receiver) were manufactured and thoroughly tested before project launch in order to prove the new engineering solutions adopted. The SENER proprietary technology of NOOR III will be applied in the next Molten Salt Tower plants that will follow in other countries, such as South Africa, Chile and Australia.

  5. Work Keys: Developing the Assessments.

    ERIC Educational Resources Information Center

    McLarty, Joyce R.

    The American College Testing Program is developing a new program, Work Keys, a system to develop and assess employability skills. It consists of four components: (1) a systematic process for profiling job skill requirements; (2) assessments that measure learners' job skill levels; (3) procedures and formats for conveying assessment results so they…

  6. Universal distribution of component frequencies in biological and technological systems

    PubMed Central

    Pang, Tin Yau; Maslov, Sergei

    2013-01-01

    Bacterial genomes and large-scale computer software projects both consist of a large number of components (genes or software packages) connected via a network of mutual dependencies. Components can be easily added or removed from individual systems, and their use frequencies vary over many orders of magnitude. We study this frequency distribution in genomes of ∼500 bacterial species and in over 2 million Linux computers and find that in both cases it is described by the same scale-free power-law distribution with an additional peak near the tail of the distribution corresponding to nearly universal components. We argue that the existence of a power law distribution of frequencies of components is a general property of any modular system with a multilayered dependency network. We demonstrate that the frequency of a component is positively correlated with its dependency degree given by the total number of upstream components whose operation directly or indirectly depends on the selected component. The observed frequency/dependency degree distributions are reproduced in a simple mathematically tractable model introduced and analyzed in this study. PMID:23530195

  7. Omnichannel Customer Behavior: Key Drivers of Technology Acceptance and Use and Their Effects on Purchase Intention

    PubMed Central

    Juaneda-Ayensa, Emma; Mosquera, Ana; Sierra Murillo, Yolanda

    2016-01-01

    The advance of the Internet and new technologies over the last decade has transformed the retailing panorama. More and more channels are emerging, causing consumers to change their habits and shopping behavior. An omnichannel strategy is a form of retailing that, by enabling real interaction, allows customers to shop across channels anywhere and at any time, thereby providing them with a unique, complete, and seamless shopping experience that breaks down the barriers between channels. This paper aims to identify the factors that influence omnichannel consumers' behavior through their acceptance of and intention to use new technologies during the shopping process. To this end, an original model was developed to explain omnichannel shopping behavior based on the variables used in the UTAUT2 model and two additional factors: personal innovativeness and perceived security. The model was tested with a sample of 628 Spanish customers of the store Zara who had used at least two channels during their most recent shopping journey. The results indicate that the key determinants of purchase intention in an omnichannel context are, in order of importance: personal innovativeness, effort expectancy, and performance expectancy. The theoretical and managerial implications are discussed. PMID:27516749

  8. Omnichannel Customer Behavior: Key Drivers of Technology Acceptance and Use and Their Effects on Purchase Intention.

    PubMed

    Juaneda-Ayensa, Emma; Mosquera, Ana; Sierra Murillo, Yolanda

    2016-01-01

    The advance of the Internet and new technologies over the last decade has transformed the retailing panorama. More and more channels are emerging, causing consumers to change their habits and shopping behavior. An omnichannel strategy is a form of retailing that, by enabling real interaction, allows customers to shop across channels anywhere and at any time, thereby providing them with a unique, complete, and seamless shopping experience that breaks down the barriers between channels. This paper aims to identify the factors that influence omnichannel consumers' behavior through their acceptance of and intention to use new technologies during the shopping process. To this end, an original model was developed to explain omnichannel shopping behavior based on the variables used in the UTAUT2 model and two additional factors: personal innovativeness and perceived security. The model was tested with a sample of 628 Spanish customers of the store Zara who had used at least two channels during their most recent shopping journey. The results indicate that the key determinants of purchase intention in an omnichannel context are, in order of importance: personal innovativeness, effort expectancy, and performance expectancy. The theoretical and managerial implications are discussed.

  9. CO2 Degassing Estimates from Rift Length Analysis since Pangea Fragmentation: A Key Component of the Deep Carbon Cycle?

    NASA Astrophysics Data System (ADS)

    Brune, S.; Williams, S.; Müller, D.

    2017-12-01

    The deep carbon cycle links the carbon content of crust and mantle to Earth's surface: extensional plate boundaries and arc volcanoes release CO2 to the ocean and atmosphere while subducted lithosphere carries carbon back into the mantle. The length of extensional and convergent plate boundaries therefore exerts first-order control on solid Earth CO2 degassing rates. Here we provide a global census of plate boundary length for the last 200 million years. Focusing on rift systems, we find that the most extensive rift phase during the fragmentation of Pangea occurred in the Jurassic/Early Cretaceous with more than 50.000 km of simultaneously active continental rifts. During the Late Cretaceous, in the aftermath of this pervasive rift episode, the global rift length dropped by 60% to 20,000 km. We further find that a second pronounced rift episode with global rift lengths of up to 30,000 km started in Eocene times. A close geological link between CO2 degassing and faulting has been documented in currently active rift systems worldwide. Regional-scale CO2 flux densities at rift segments in Africa, Europe, and New Zealand feature an annual average value of 200 t of CO2 per km2. Assuming that the release of CO2 scales with rift length, we show that rift-related CO2 degassing rates during the two major Mesozoic and Cenozoic rift episodes reached more than 300% of present-day values. Most importantly, the timing of enhanced CO2 degassing from continental rifts correlates with two well-known periods of elevated atmospheric CO2 in the Mesozoic and Cenozoic as evidenced by multiple independent proxy indicators. Compiling the length of other plate boundaries (mid-ocean ridges, subduction zones, continental arcs) through time, we do not reproduce such a correlation. Finally, we conduct numerical carbon cycle models that account for key feedback-mechanisms of the long-term carbon cycle. We find that only those models that feature a strong rift degassing component reproduce the

  10. Identifying Key Components of Teaching and Learning in a STEM School

    ERIC Educational Resources Information Center

    Morrison, Judith; Roth McDuffie, Amy; French, Brian

    2015-01-01

    This study was conducted at an innovative science, technology, engineering, and mathematics high school, providing a rich contextual description of the teaching and learning at the school, specifically focusing on problem solving and inquiry approaches, and students' motivation, social interactions, and collaborative work. Data were collected…

  11. An Integrated Methodology to Assess Compliance with Delphi Survey Key Components of Yoga Interventions for Musculoskeletal Conditions as Applied in a Systematic Review of Fibromyalgia Studies.

    PubMed

    Fischer-White, Tamara G; Anderson, Joel G; Taylor, Ann Gill

    2016-01-01

    The objective of this article was to present a methodology incorporating existing guidelines and tools for systematic reviews and to evaluate the Delphi survey 33 key component recommendations of yoga interventions for musculoskeletal conditions as a tool for a systematic review in fibromyalgia studies. Databases searched included PubMed, Ovid Medline, PsychINFO, the Cochrane Library, CINAHL, ALT HealthWatch, PEDro, and Web of Science. Selected were articles published between November 14, 2004 and November 13, 2014, written in English, reporting original research of yoga interventions for adults with fibromyalgia. Six articles met the inclusion criteria, revealing that three yoga styles ("Relaxing" yoga, Yoga of Awareness, and Hatha yoga) have been assessed in persons with fibromyalgia. Overall, reporting compliance with the 33 key components ranged from 39.4% to 84.8%, with a mean adherence rate of 62.63% ± 17.74. None of the authors used an accepted reporting guideline; specific components of asana, pranayama, relaxation, and mindfulness practices that would have been incorporated into the interventions tested were identified in only 33.33% of the articles reviewed; and none of the articles included detailed, replicable descriptions of the interventions. This systematic review supports the need for comprehensive yoga research guidelines. Findings reveal a lack of reporting of intervention details, the need to report a disease-specific rationale for selection of the particular yoga style used for the intervention, and that a limited number of yoga styles have been investigated in persons with fibromyalgia. Copyright © 2016 Elsevier Inc. All rights reserved.

  12. Automated secured cost effective key refreshing technique to enhance WiMAX privacy key management

    NASA Astrophysics Data System (ADS)

    Sridevi, B.; Sivaranjani, S.; Rajaram, S.

    2013-01-01

    In all walks of life the way of communication is transformed by the rapid growth of wireless communication and its pervasive use. A wireless network which is fixed and richer in bandwidth is specified as IEEE 802.16, promoted and launched by an industrial forum is termed as Worldwide Interoperability for Microwave Access (WiMAX). This technology enables seamless delivery of wireless broadband service for fixed and/or mobile users. The obscurity is the long delay which occurs during the handoff management in every network. Mobile WiMAX employs an authenticated key management protocol as a part of handoff management in which the Base Station (BS) controls the distribution of keying material to the Mobile Station (MS). The protocol employed is Privacy Key Management Version 2- Extensible Authentication Protocol (PKMV2-EAP) which is responsible for the normal and periodical authorization of MSs, reauthorization as well as key refreshing. Authorization key (AK) and Traffic Encryption key (TEK) plays a vital role in key exchange. When the lifetime of key expires, MS has to request for a new key to BS which in turn leads to repetition of authorization, authentication as well as key exchange. To avoid service interruption during reauthorization , two active keys are transmitted at the same time by BS to MS. The consequences of existing work are hefty amount of bandwidth utilization, time consumption and large storage. It is also endured by Man in the Middle attack and Impersonation due to lack of security in key exchange. This paper designs an automatic mutual refreshing of keys to minimize bandwidth utilization, key storage and time consumption by proposing Previous key and Iteration based Key Refreshing Function (PKIBKRF). By integrating PKIBKRF in key generation, the simulation results indicate that 21.8% of the bandwidth and storage of keys are reduced and PKMV2 mutual authentication time is reduced by 66.67%. The proposed work is simulated with Qualnet model and

  13. Energy Efficient Engine (E3) combustion system component technology performance report

    NASA Technical Reports Server (NTRS)

    Burrus, D. L.; Chahrour, C. A.; Foltz, H. L.; Sabla, P. E.; Seto, S. P.; Taylor, J. R.

    1984-01-01

    The Energy Efficient Engine (E3) combustor effort was conducted as part of the overall NASA/GE E3 Program. This effort included the selection of an advanced double-annular combustion system design. The primary intent of this effort was to evolve a design that meets the stringent emissions and life goals of the E3, as well as all of the usual performance requirements of combustion systems for modern turbofan engines. Numerous detailed design studies were conducted to define the features of the combustion system design. Development test hardware was fabricated, and an extensive testing effort was undertaken to evaluate the combustion system subcomponents in order to verify and refine the design. Technology derived from this effort was incorporated into the engine combustion hardware design. The advanced engine combustion system was then evaluated in component testing to verify the design intent. What evolved from this effort was an advanced combustion system capable of satisfying all of the combustion system design objectives and requirements of the E3.

  14. Optical CDMA components requirements

    NASA Astrophysics Data System (ADS)

    Chan, James K.

    1998-08-01

    Optical CDMA is a complementary multiple access technology to WDMA. Optical CDMA potentially provides a large number of virtual optical channels for IXC, LEC and CLEC or supports a large number of high-speed users in LAN. In a network, it provides asynchronous, multi-rate, multi-user communication with network scalability, re-configurability (bandwidth on demand), and network security (provided by inherent CDMA coding). However, optical CDMA technology is less mature in comparison to WDMA. The components requirements are also different from WDMA. We have demonstrated a video transport/switching system over a distance of 40 Km using discrete optical components in our laboratory. We are currently pursuing PIC implementation. In this paper, we will describe the optical CDMA concept/features, the demonstration system, and the requirements of some critical optical components such as broadband optical source, broadband optical amplifier, spectral spreading/de- spreading, and fixed/programmable mask.

  15. [Development and application of component-based Chinese medicine theory].

    PubMed

    Zhang, Jun-Hua; Fan, Guan-Wei; Zhang, Han; Fan, Xiao-Hui; Wang, Yi; Liu, Li-Mei; Li, Chuan; Gao, Yue; Gao, Xiu-Mei; Zhang, Bo-Li

    2017-11-01

    Traditional Chinese medicine (TCM) prescription is the main therapies for disease prevention and treatment in Chinese medicine. Following the guidance of the theory of TCM and developing drug by composing prescriptions of TCM materials and pieces, it is a traditional application mode of TCM, and still widely used in clinic. TCM prescription has theoretical advantages and rich clinical application experience in dealing with multi-factor complex diseases, but scientific research is relatively weak. The lack of scientific cognition of the effective substances and mechanism of Chinese medicine leads to insufficient understanding of the efficacy regularity, which affects the stability of effect and hinders the improvement of quality of Chinese medicinal products. Component-based Chinese medicine (CCM) is an innovation based on inheritance, which breaks through the tradition of experience-based prescription and realize the transformation of compatibility from herbal pieces to components. CCM is an important achievement during the research process of modernization of Chinese medicine. Under the support of three national "973" projects, in order to reveal the scientific connotation of the prescription compatibility theory and develop innovative Chinese drugs, we have launched theoretical innovation and technological innovation around the "two relatively clear", and opened up the research field of CCM. CCM is an innovation based on inheritance, breaking through the tradition of experience based prescription, and realizing the transformation from compatibility of herbal pieces to component compatibility, which is an important achievement of the modernization of traditional Chinese medicine. In the past more than 10 years, with the deepening of research and the expansion of application, the theory and methods of CCM and efficacy-oriented compatibility have been continuously improved. The value of CCM is not only in developing new drug, more important is to build a

  16. The distinction between key ideas in teaching school physics and key ideas in the discipline of physics

    NASA Astrophysics Data System (ADS)

    Deng, Zongyi

    2001-05-01

    The distinction between key ideas in teaching a high school science and key ideas in the corresponding discipline of science has been largely ignored in scholarly discourse about what science teachers should teach and about what they should know. This article clarifies this distinction through exploring how and why key ideas in teaching high school physics differ from key ideas in the discipline of physics. Its theoretical underpinnings include Dewey's (1902/1990) distinction between the psychological and the logical and Harré's (1986) epistemology of science. It analyzes how and why the key ideas in teaching color, the speed of light, and light interference at the high school level differ from the key ideas at the disciplinary level. The thesis is that key ideas in teaching high school physics can differ from key ideas in the discipline in some significant ways, and that the differences manifest Dewey's distinction. As a result, the article challenges the assumption of equating key ideas in teaching a high school science with key ideas in the corresponding discipline of science, and the assumption that having a college degree in science is sufficient to teach high school science. Furthermore, the article expands the concept of pedagogical content knowledge by arguing that key ideas in teaching high school physics constitute an essential component.

  17. A host basal transcription factor is a key component for infection of rice by TALE-carrying bacteria

    PubMed Central

    Yuan, Meng; Ke, Yinggen; Huang, Renyan; Ma, Ling; Yang, Zeyu; Chu, Zhaohui; Xiao, Jinghua; Li, Xianghua; Wang, Shiping

    2016-01-01

    Transcription activator-like effectors (TALEs) are sequence-specific DNA binding proteins found in a range of plant pathogenic bacteria, where they play important roles in host-pathogen interactions. However, it has been unclear how TALEs, after they have been injected into the host cells, activate transcription of host genes required for infection success. Here, we show that the basal transcription factor IIA gamma subunit TFIIAγ5 from rice is a key component for infection by the TALE-carrying bacterium Xanthomonas oryzae pv. oryzae, the causal agent for bacterial blight. Direct interaction of several TALEs with TFIIAγ5 is required for activation of disease susceptibility genes. Conversely, reduced expression of the TFIIAγ5 host gene limits the induction of susceptibility genes and thus decreases bacterial blight symptoms. Suppression or mutation of TFIIAγ5 can also reduce bacterial streak, another devastating disease of rice caused by TALE-carrying X. oryzae pv. oryzicola. These results have important implications for formulating a widely applicable strategy with which to improve resistance of plants to TALE-carrying pathogens. DOI: http://dx.doi.org/10.7554/eLife.19605.001 PMID:27472897

  18. Can eye-tracking technology improve situational awareness in paramedic clinical education?

    PubMed

    Williams, Brett; Quested, Andrew; Cooper, Simon

    2013-01-01

    Human factors play a significant part in clinical error. Situational awareness (SA) means being aware of one's surroundings, comprehending the present situation, and being able to predict outcomes. It is a key human skill that, when properly applied, is associated with reducing medical error: eye-tracking technology can be used to provide an objective and qualitative measure of the initial perception component of SA. Feedback from eye-tracking technology can be used to improve the understanding and teaching of SA in clinical contexts, and consequently, has potential for reducing clinician error and the concomitant adverse events.

  19. Measurement component technology. Volume 1: Cryogenic pressure measurement technology, high pressure flange seals, hydrogen embrittlement of pressure transducer material, close coupled versus remote transducer installation and temperature compensation of pressure transducers

    NASA Technical Reports Server (NTRS)

    Hayakawa, K. K.; Udell, D. R.; Iwata, M. M.; Lytle, C. F.; Chrisco, R. M.; Greenough, C. S.; Walling, J. A.

    1972-01-01

    The results are presented of an investigation into the availability and performance capability of measurement components in the area of cryogenic temperature, pressure, flow and liquid detection components and high temperature strain gages. In addition, technical subjects allied to the components were researched and discussed. These selected areas of investigation were: (1) high pressure flange seals, (2) hydrogen embrittlement of pressure transducer diaphragms, (3) The effects of close-coupled versus remote transducer installation on pressure measurement, (4) temperature transducer configuration effects on measurements, and (5) techniques in temperature compensation of strain gage pressure transducers. The purpose of the program was to investigate the latest design and application techniques in measurement component technology and to document this information along with recommendations for upgrading measurement component designs for future S-2 derivative applications. Recommendations are provided for upgrading existing state-of-the-art in component design, where required, to satisfy performance requirements of S-2 derivative vehicles.

  20. Extending key sharing: how to generate a key tightly coupled to a network security policy

    NASA Astrophysics Data System (ADS)

    Kazantzidis, Matheos

    2006-04-01

    Current state of the art security policy technologies, besides the small scale limitation and largely manual nature of accompanied management methods, are lacking a) in real-timeliness of policy implementation and b) vulnerabilities and inflexibility stemming from the centralized policy decision making; even if, for example, a policy description or access control database is distributed, the actual decision is often a centralized action and forms a system single point of failure. In this paper we are presenting a new fundamental concept that allows implement a security policy by a systematic and efficient key distribution procedure. Specifically, we extend the polynomial Shamir key splitting. According to this, a global key is split into n parts, any k of which can re-construct the original key. In this paper we present a method that instead of having "any k parts" be able to re-construct the original key, the latter can only be reconstructed if keys are combined as any access control policy describes. This leads into an easily deployable key generation procedure that results a single key per entity that "knows" its role in the specific access control policy from which it was derived. The system is considered efficient as it may be used to avoid expensive PKI operations or pairwise key distributions as well as provides superior security due to its distributed nature, the fact that the key is tightly coupled to the policy, and that policy change may be implemented easier and faster.

  1. Effects of "D"-Amphetamine and Ethanol on Variable and Repetitive Key-Peck Sequences in Pigeons

    ERIC Educational Resources Information Center

    Ward, Ryan D.; Bailey, Ericka M.; Odum, Amy L.

    2006-01-01

    This experiment assessed the effects of "d"-Amphetamine and ethanol on reinforced variable and repetitive key-peck sequences in pigeons. Pigeons responded on two keys under a multiple schedule of Repeat and Vary components. In the Repeat component, completion of a target sequence of right, right, left, left resulted in food. In the Vary component,…

  2. Optoelectronic Technology Consortium: Precompetitive Consortium for Optoelectronic Interconnect Technology

    DTIC Science & Technology

    1992-09-01

    demonstrating the producibility of optoelectronic components for high-density/high-data-rate processors and accelerating the insertion of this technology...technology development stage, OETC will advance the development of optical components, produce links for a multiboard processor testbed demonstration, and...components that are affordable, initially at <$100 per line, and reliable, with a li~e BER᝺-15 and MTTF >10 6 hours. Under the OETC program, Honeywell will

  3. Equipping the 2015 Chemical Technology Workforce: Partnering with Key Stakeholders

    ERIC Educational Resources Information Center

    Aronson, Blake; Wesemann, Jodi

    2007-01-01

    The opportunities and challenges associated with establishing and sustaining successful chemistry-based technology programs were discussed at Equipping the 2015 Chemical Technology Workforce, a Presidential Event held at the Fall 2006 ACS National Meeting, kicking off an initiative by the same name. The initiative is based on the recent ACS…

  4. Mechanically Pumped Fluid Loop (MPFL) Technologies for Thermal Control of Future Mars Rovers

    NASA Technical Reports Server (NTRS)

    Birur, Gaj; Bhandari, Pradeep; Prina, Mauro; Bame, Dave; Yavrouian, Andre; Plett, Gary

    2006-01-01

    Mechanically pumped fluid loop has been the basis of thermal control architecture for the last two Mars lander and rover missions and is the key part of the MSL thermal architecture. Several MPFL technologies are being developed for the MSL rover include long-life pumps, thermal control valves, mechanical fittings for use with CFC-11 at elevated temperatures of approx.100 C. Over three years of life tests and chemical compatibility tests on these MPFL components show that MPFL technology is mature for use on MSL. The advances in MPFL technologies for MSL Rover will benefit any future MPFL applications on NASA s Moon, Mars and Beyond Program.

  5. Structure-activity modelling of essential oils, their components, and key molecular parameters and descriptors.

    PubMed

    Owen, Lucy; Laird, Katie; Wilson, Philippe B

    2018-04-01

    Many essential oil components are known to possess broad spectrum antimicrobial activity, including against antibiotic resistant bacteria. These compounds may be a useful source of new and novel antimicrobials. However, there is limited research on the structure-activity relationship (SAR) of essential oil compounds, which is important for target identification and lead optimization. This study aimed to elucidate SARs of essential oil components from experimental and literature sources. Minimum Inhibitory Concentrations (MICs) of essential oil components were determined against Escherichia coli and Staphylococcus aureus using a microdilution method and then compared to those in published in literature. Of 12 essential oil components tested, carvacrol and cuminaldehyde were most potent with MICs of 1.98 and 2.10 mM, respectively. The activity of 21 compounds obtained from the literature, MICs ranged from 0.004 mM for limonene to 36.18 mM for α-terpineol. A 3D qualitative SAR model was generated from MICs using FORGE software by consideration of electrostatic and steric parameters. An r 2 value of 0.807 for training and cross-validation sets was achieved with the model developed. Ligand efficiency was found to correlate well to the observed activity (r 2  = 0.792), while strongly negative electrostatic regions were present in potent molecules. These descriptors may be useful for target identification of essential oils or their major components in antimicrobial/drug development. Copyright © 2017 Elsevier Ltd. All rights reserved.

  6. Multi-user quantum key distribution with entangled photons from an AlGaAs chip

    NASA Astrophysics Data System (ADS)

    Autebert, C.; Trapateau, J.; Orieux, A.; Lemaître, A.; Gomez-Carbonell, C.; Diamanti, E.; Zaquine, I.; Ducci, S.

    2016-12-01

    In view of real-world applications of quantum information technologies, the combination of miniature quantum resources with existing fibre networks is a crucial issue. Among such resources, on-chip entangled photon sources play a central role for applications spanning quantum communications, computing and metrology. Here, we use a semiconductor source of entangled photons operating at room temperature in conjunction with standard telecom components to demonstrate multi-user quantum key distribution, a core protocol for securing communications in quantum networks. The source consists of an AlGaAs chip-emitting polarisation entangled photon pairs over a large bandwidth in the main telecom band around 1550 nm without the use of any off-chip compensation or interferometric scheme; the photon pairs are directly launched into a dense wavelength division multiplexer (DWDM) and secret keys are distributed between several pairs of users communicating through different channels. We achieve a visibility measured after the DWDM of 87% and show long-distance key distribution using a 50-km standard telecom fibre link between two network users. These results illustrate a promising route to practical, resource-efficient implementations adapted to quantum network infrastructures.

  7. Overview of RFID technology and its applications in the food industry.

    PubMed

    Kumar, P; Reinitz, H W; Simunovic, J; Sandeep, K P; Franzon, P D

    2009-10-01

    Radio frequency identification (RFID) is an alternative technology with a potential to replace traditional universal product code (UPC) barcodes. RFID enables identification of an object from a distance without requiring a line of sight. RFID tags can also incorporate additional data such as details of product and manufacturer and can transmit measured environmental factors such as temperature and relative humidity. This article presents key concepts and terminology related to RFID technology and its applications in the food industry. Components and working principles of an RFID system are described. Numerous applications of RFID technology in the food industry (supply chain management, temperature monitoring of foods, and ensuring food safety) are discussed. Challenges in implementation of RFID technology are also discussed in terms of read range, read accuracy, nonuniform standards, cost, recycling issues, privacy, and security concerns.

  8. Low-cost manufacturing of the point focus concentrating module and its key component, the Fresnel lens. Final subcontract report, 31 January 1991--6 May 1991

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Saifee, T.; Konnerth, A. III

    1991-11-01

    Solar Kinetics, Inc. (SKI) has been developing point-focus concentrating PV modules since 1986. SKI is currently in position to manufacture between 200 to 600 kilowatts annually of the current design by a combination of manual and semi-automated methods. This report reviews the current status of module manufacture and specifies the required approach to achieve a high-volume manufacturing capability and low cost. The approach taken will include process development concurrent with module design for automated manufacturing. The current effort reviews the major manufacturing costs and identifies components and processes whose improvements would produce the greatest effect on manufacturability and cost reduction.more » The Fresnel lens is one such key component. Investigating specific alternative manufacturing methods and sources has substantially reduced the lens costs and has exceeded the DOE cost-reduction goals. 15 refs.« less

  9. Technical Education--The Key to Sustainable Technological Development

    ERIC Educational Resources Information Center

    Odo, J. U.; Okafor, W. C.; Odo, A. L.; Ejikeugwu, L. N.; Ugwuoke, C. N.

    2017-01-01

    Technical education has been identified as one of the most effective human resource development that needs to be embraced for rapid industrialization and sustainable technological development of any nation. Technical education has been an integral part of national development in many societies because of its impact on productivity and economic…

  10. Advances in compact manufacturing for shape and performance controllability of large-scale components-a review

    NASA Astrophysics Data System (ADS)

    Qin, Fangcheng; Li, Yongtang; Qi, Huiping; Ju, Li

    2017-01-01

    Research on compact manufacturing technology for shape and performance controllability of metallic components can realize the simplification and high-reliability of manufacturing process on the premise of satisfying the requirement of macro/micro-structure. It is not only the key paths in improving performance, saving material and energy, and green manufacturing of components used in major equipments, but also the challenging subjects in frontiers of advanced plastic forming. To provide a novel horizon for the manufacturing in the critical components is significant. Focused on the high-performance large-scale components such as bearing rings, flanges, railway wheels, thick-walled pipes, etc, the conventional processes and their developing situations are summarized. The existing problems including multi-pass heating, wasting material and energy, high cost and high-emission are discussed, and the present study unable to meet the manufacturing in high-quality components is also pointed out. Thus, the new techniques related to casting-rolling compound precise forming of rings, compact manufacturing for duplex-metal composite rings, compact manufacturing for railway wheels, and casting-extruding continuous forming of thick-walled pipes are introduced in detail, respectively. The corresponding research contents, such as casting ring blank, hot ring rolling, near solid-state pressure forming, hot extruding, are elaborated. Some findings in through-thickness microstructure evolution and mechanical properties are also presented. The components produced by the new techniques are mainly characterized by fine and homogeneous grains. Moreover, the possible directions for further development of those techniques are suggested. Finally, the key scientific problems are first proposed. All of these results and conclusions have reference value and guiding significance for the integrated control of shape and performance in advanced compact manufacturing.

  11. Formation of a New Entity to Support Effective Use of Technology in Medical Education: The Student Technology Committee

    PubMed Central

    Adams, Ryan Christopher; Ahmed, S. Toufeeq; Spickard, Anderson

    2015-01-01

    Background As technology in medical education expands from teaching tool to crucial component of curricular programming, new demands arise to innovate and optimize educational technology. While the expectations of today’s digital native students are significant, their experience and unique insights breed new opportunities to involve them as stakeholders in tackling educational technology challenges. Objective The objective of this paper is to present our experience with a novel medical student-led and faculty-supported technology committee that was developed at Vanderbilt University School of Medicine to harness students’ valuable input in a comprehensive fashion. Key lessons learned through the initial successes and challenges of implementing our model are also discussed. Methods A committee was established with cooperation of school administration, a faculty advisor with experience launching educational technologies, and a group of students passionate about this domain. Committee membership is sustained through annual selective recruitment of interested students. Results The committee serves 4 key functions: acting as liaisons between students and administration; advising development of institutional educational technologies; developing, piloting, and assessing new student-led educational technologies; and promoting biomedical and educational informatics within the school community. Participating students develop personally and professionally, contribute to program implementation, and extend the field’s understanding by pursuing research initiatives. The institution benefits from rapid improvements to educational technologies that meet students’ needs and enhance learning opportunities. Students and the institution also gain from fostering a campus culture of awareness and innovation in informatics and medical education. The committee’s success hinges on member composition, school leadership buy-in, active involvement in institutional activities, and

  12. Key Management Infrastructure Increment 2 (KMI Inc 2)

    DTIC Science & Technology

    2016-03-01

    2016 Major Automated Information System Annual Report Key Management Infrastructure Increment 2 (KMI Inc 2) Defense Acquisition Management...PB - President’s Budget RDT&E - Research, Development, Test, and Evaluation SAE - Service Acquisition Executive TBD - To Be Determined TY - Then...Assigned: April 6, 2015 Program Information Program Name Key Management Infrastructure Increment 2 (KMI Inc 2) DoD Component DoD The acquiring DoD

  13. Technology initiatives for the autonomous guidance, navigation, and control of single and multiple satellites

    NASA Astrophysics Data System (ADS)

    Croft, John; Deily, John; Hartman, Kathy; Weidow, David

    1998-01-01

    In the twenty-first century, NASA envisions frequent low-cost missions to explore the solar system, observe the universe, and study our planet. To realize NASA's goal, the Guidance, Navigation, and Control Center (GNCC) at the Goddard Space Flight Center sponsors technology programs that enhance spacecraft performance, streamline processes and ultimately enable cheaper science. Our technology programs encompass control system architectures, sensor and actuator components, electronic systems, design and development of algorithms, embedded systems and space vehicle autonomy. Through collaboration with government, universities, non-profit organizations, and industry, the GNCC incrementally develops key technologies that conquer NASA's challenges. This paper presents an overview of several innovative technology initiatives for the autonomous guidance, navigation, and control (GN&C) of satellites.

  14. Seaworthy Quantum Key Distribution Design and Validation (SEAKEY)

    DTIC Science & Technology

    2016-03-10

    Contractor Address: 10 Moulton Street, Cambridge, MA 02138 Title of the Project: Seaworthy Quantum Key Distribution Design and Validation (SEAKEY...Technologies Kathryn Carson Program Manager Quantum Information Processing 2 | P a g e Approved for public release; distribution is...we have continued work calculating the key rates achievable parametrically with receiver performance. In addition, we describe the initial designs

  15. Oncology Modeling for Fun and Profit! Key Steps for Busy Analysts in Health Technology Assessment.

    PubMed

    Beca, Jaclyn; Husereau, Don; Chan, Kelvin K W; Hawkins, Neil; Hoch, Jeffrey S

    2018-01-01

    In evaluating new oncology medicines, two common modeling approaches are state transition (e.g., Markov and semi-Markov) and partitioned survival. Partitioned survival models have become more prominent in oncology health technology assessment processes in recent years. Our experience in conducting and evaluating models for economic evaluation has highlighted many important and practical pitfalls. As there is little guidance available on best practices for those who wish to conduct them, we provide guidance in the form of 'Key steps for busy analysts,' who may have very little time and require highly favorable results. Our guidance highlights the continued need for rigorous conduct and transparent reporting of economic evaluations regardless of the modeling approach taken, and the importance of modeling that better reflects reality, which includes better approaches to considering plausibility, estimating relative treatment effects, dealing with post-progression effects, and appropriate characterization of the uncertainty from modeling itself.

  16. Heavy hydrocarbon main injector technology

    NASA Technical Reports Server (NTRS)

    Fisher, S. C.; Arbit, H. A.

    1988-01-01

    One of the key components of the Advanced Launch System (ALS) is a large liquid rocket, booster engine. To keep the overall vehicle size and cost down, this engine will probably use liquid oxygen (LOX) and a heavy hydrocarbon, such as RP-1, as propellants and operate at relatively high chamber pressures to increase overall performance. A technology program (Heavy Hydrocarbon Main Injector Technology) is being studied. The main objective of this effort is to develop a logic plan and supporting experimental data base to reduce the risk of developing a large scale (approximately 750,000 lb thrust), high performance main injector system. The overall approach and program plan, from initial analyses to large scale, two dimensional combustor design and test, and the current status of the program are discussed. Progress includes performance and stability analyses, cold flow tests of injector model, design and fabrication of subscale injectors and calorimeter combustors for performance, heat transfer, and dynamic stability tests, and preparation of hot fire test plans. Related, current, high pressure, LOX/RP-1 injector technology efforts are also briefly discussed.

  17. Key enablers to facilitate healthy behavior change: workshop summary.

    PubMed

    Teyhen, Deydre S; Aldag, Matt; Centola, Damon; Edinborough, Elton; Ghannadian, Jason D; Haught, Andrea; Jackson, Theresa; Kinn, Julie; Kunkler, Kevin J; Levine, Betty; Martindale, Valerie E; Neal, David; Snyder, Leslie B; Styn, Mindi A; Thorndike, Frances; Trabosh, Valerie; Parramore, David J

    2014-05-01

    The increases in preventable chronic diseases and the rising costs of health care are unsustainable. The US Army Surgeon General's vision to transition from a health care system to a system of health requires the identification of key health enablers to facilitate the adoption of healthy behaviors. In support of this vision, the US Army Telemedicine and Advanced Technology Research Center hosted a workshop in April 2013 titled "Incentives to Create and Sustain Change for Health." Members of government and academia participated to identify key health enablers that could ultimately be leveraged by technology. The key health enablers discussed included (1) public health messaging, (2) changing health habits and the environmental influence on health, (3) goal setting and tracking, (4) the role of incentives in behavior-change intervention, and (5) the role of peer and social networks on change. This report summarizes leading evidence and the group consensus on evidence-based practices with respect to the key enablers in creating healthy behavior change.

  18. An SSH key management system: easing the pain of managing key/user/account associations

    NASA Astrophysics Data System (ADS)

    Arkhipkin, D.; Betts, W.; Lauret, J.; Shiryaev, A.

    2008-07-01

    Cyber security requirements for secure access to computing facilities often call for access controls via gatekeepers and the use of two-factor authentication. Using SSH keys to satisfy the two factor authentication requirement has introduced a potentially challenging task of managing the keys and their associations with individual users and user accounts. Approaches for a facility with the simple model of one remote user corresponding to one local user would not work at facilities that require a many-to-many mapping between users and accounts on multiple systems. We will present an SSH key management system we developed, tested and deployed to address the many-to-many dilemma in the environment of the STAR experiment. We will explain its use in an online computing context and explain how it makes possible the management and tracing of group account access spread over many sub-system components (data acquisition, slow controls, trigger, detector instrumentation, etc.) without the use of shared passwords for remote logins.

  19. Status of 20 kHz space station power distribution technology

    NASA Technical Reports Server (NTRS)

    Hansen, Irving G.

    1988-01-01

    Power Distribution on the NASA Space Station will be accomplished by a 20 kHz sinusoidal, 440 VRMS, single phase system. In order to minimize both system complexity and the total power coversion steps required, high frequency power will be distributed end-to-end in the system. To support the final design of flight power system hardware, advanced development and demonstrations have been made on key system technologies and components. The current status of this program is discussed.

  20. Tribology and Mechanical Components Branch Overview

    NASA Technical Reports Server (NTRS)

    Handschuh, Robert F.

    2010-01-01

    An overview of NASA Glenn Research Center's Tribology & Mechanical Components Branch is provided. Work in space mechanisms, seals, oil-free turbomachinery, and mechanical components is presented. An overview of current research for these technology areas is contained in this overview.

  1. Enhancing mung bean hydration using the ultrasound technology: description of mechanisms and impact on its germination and main components

    NASA Astrophysics Data System (ADS)

    Miano, Alberto Claudio; Pereira, Jessica Da Costa; Castanha, Nanci; Júnior, Manoel Divino Da Matta; Augusto, Pedro Esteves Duarte

    2016-12-01

    The ultrasound technology was successfully used to improve the mass transfer processes on food. However, the study of this technology on the grain hydration and on its main components properties was still not appropriately described. This work studied the application of the ultrasound technology on the hydration process of mung beans (Vigna radiata). This grain showed sigmoidal hydration behavior with a specific water entrance pathway. The ultrasound reduced ~25% of the hydration process time. In addition, this technology caused acceleration of the seed germination - and some hypothesis for this enhancement were proposed. Moreover, it was demonstrated that the ultrasound did not change both structure and pasting properties of the bean starch. Finally, the flour rheological properties proved that the ultrasound increased its apparent viscosity, and as the starch was not modified, this alteration was attributed to the proteins. All these results are very desirable for industry since the ultrasound technology improves the hydration process without altering the starch properties, accelerates the germination process (that is important for the malting and sprouting process) and increases the flour apparent viscosity, which is desirable to produce bean-based products that need higher consistency.

  2. EHR in emergency rooms: exploring the effect of key information components on main complaints.

    PubMed

    Ben-Assuli, Ofir; Shabtai, Itamar; Leshno, Moshe; Hill, Shawndra

    2014-04-01

    This study characterizes the information components associated with improved medical decision-making in the emergency room (ER). We looked at doctors' decisions to use or not to use information available to them on an electronic health record (EHR) and a Health Information Exchange (HIE) network, and tested for associations between their decision and parameters related to healthcare outcomes and processes. Using information components from the EHR and HIE was significantly related to improved quality of healthcare processes. Specifically, it was associated with both a reduction in potentially avoidable admissions as well as a reduction in rapid readmissions. Overall, the three information components; namely, previous encounters, imaging, and lab results emerged as having the strongest relationship with physicians' decisions to admit or discharge. Certain information components, however, presented an association between the diagnosis and the admission decisions (blood pressure was the most strongly associated parameter in cases of chest pain complaints and a previous surgical record for abdominal pain). These findings show that the ability to access patients' medical history and their long term health conditions (via the EHR), including information about medications, diagnoses, recent procedures and laboratory tests is critical to forming an appropriate plan of care and eventually making more accurate admission decisions.

  3. Evaluation of novel technologies for the miniaturization of flash imaging lidar

    NASA Astrophysics Data System (ADS)

    Mitev, V.; Pollini, A.; Haesler, J.; Perenzoni, D.; Stoppa, D.; Kolleck, Christian; Chapuy, M.; Kervendal, E.; Pereira do Carmo, João.

    2017-11-01

    Planetary exploration constitutes one of the main components in the European Space activities. Missions to Mars, Moon and asteroids are foreseen where it is assumed that the human missions shall be preceded by robotic exploitation flights. The 3D vision is recognised as a key enabling technology in the relative proximity navigation of the space crafts, where imaging LiDAR is one of the best candidates for such 3D vision sensor.

  4. Seaworthy Quantum Key Distribution Design and Validation (SEAKEY)

    DTIC Science & Technology

    2015-05-27

    Address: 10 Moulton Street, Cambridge, MA 02138 Title of the Project: Seaworthy Quantum Key Distribution Design and Validation (SEAKEY...Technologies Kathryn Carson Program Manager Quantum Information Processing Report Documentation Page Form ApprovedOMB No. 0704-0188 Public...2016 4. TITLE AND SUBTITLE Seaworthy Quantum Key Distribution Design and Validation (SEAKEY) 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM

  5. DNA based random key generation and management for OTP encryption.

    PubMed

    Zhang, Yunpeng; Liu, Xin; Sun, Manhui

    2017-09-01

    One-time pad (OTP) is a principle of key generation applied to the stream ciphering method which offers total privacy. The OTP encryption scheme has proved to be unbreakable in theory, but difficult to realize in practical applications. Because OTP encryption specially requires the absolute randomness of the key, its development has suffered from dense constraints. DNA cryptography is a new and promising technology in the field of information security. DNA chromosomes storing capabilities can be used as one-time pad structures with pseudo-random number generation and indexing in order to encrypt the plaintext messages. In this paper, we present a feasible solution to the OTP symmetric key generation and transmission problem with DNA at the molecular level. Through recombinant DNA technology, by using only sender-receiver known restriction enzymes to combine the secure key represented by DNA sequence and the T vector, we generate the DNA bio-hiding secure key and then place the recombinant plasmid in implanted bacteria for secure key transmission. The designed bio experiments and simulation results show that the security of the transmission of the key is further improved and the environmental requirements of key transmission are reduced. Analysis has demonstrated that the proposed DNA-based random key generation and management solutions are marked by high security and usability. Published by Elsevier B.V.

  6. The role of technology and engineering models in transforming healthcare.

    PubMed

    Pavel, Misha; Jimison, Holly Brugge; Wactlar, Howard D; Hayes, Tamara L; Barkis, Will; Skapik, Julia; Kaye, Jeffrey

    2013-01-01

    The healthcare system is in crisis due to challenges including escalating costs, the inconsistent provision of care, an aging population, and high burden of chronic disease related to health behaviors. Mitigating this crisis will require a major transformation of healthcare to be proactive, preventive, patient-centered, and evidence-based with a focus on improving quality-of-life. Information technology, networking, and biomedical engineering are likely to be essential in making this transformation possible with the help of advances, such as sensor technology, mobile computing, machine learning, etc. This paper has three themes: 1) motivation for a transformation of healthcare; 2) description of how information technology and engineering can support this transformation with the help of computational models; and 3) a technical overview of several research areas that illustrate the need for mathematical modeling approaches, ranging from sparse sampling to behavioral phenotyping and early detection. A key tenet of this paper concerns complementing prior work on patient-specific modeling and simulation by modeling neuropsychological, behavioral, and social phenomena. The resulting models, in combination with frequent or continuous measurements, are likely to be key components of health interventions to enhance health and wellbeing and the provision of healthcare.

  7. Lessons from the Canadian national health information technology plan for the United States: opinions of key Canadian experts.

    PubMed

    Zimlichman, Eyal; Rozenblum, Ronen; Salzberg, Claudia A; Jang, Yeona; Tamblyn, Melissa; Tamblyn, Robyn; Bates, David W

    2012-01-01

    To summarize the Canadian health information technology (HIT) policy experience and impart lessons learned to the US as it determines its policy in this area. Qualitative analysis of interviews with identified key stakeholders followed by an electronic survey. We conducted semi-structured interviews with 29 key Canadian HIT policy and opinion leaders and used a grounded theory approach to analyze the results. The informant sample was chosen to provide views from different stakeholder groups including national representatives and regional representatives from three Canadian provinces. Canadian informants believed that much of the current US direction is positive, especially regarding incentives and meaningful use, but that there are key opportunities for the US to emphasize direct engagement with providers, define a clear business case for them, sponsor large scale evaluations to assess HIT impact in a broad array of settings, determine standards but also enable access to resources needed for mid-course corrections of standards when issues are identified, and, finally, leverage implementation of digital imaging systems. Not all stakeholder groups were included, such as providers or patients. In addition, as in all qualitative research, a selection bias could be present due to the relatively small sample size. Based on Canadian experience with HIT policy, stakeholders identified as lessons for the US the need to increase direct engagement with providers and the importance of defining the business case for HIT, which can be achieved through large scale evaluations, and of recognizing and leveraging successes as they emerge.

  8. Cryogenic Propellant Storage and Transfer (CPST) Technology Maturation: Establishing a Foundation for a Technology Demonstration Mission (TDM)

    NASA Technical Reports Server (NTRS)

    Doherty, Michael P.; Meyer, Michael L.; Motil, Susan M.; Ginty, Carol A.

    2014-01-01

    As part of U.S. National Space Policy, NASA is seeking an innovative path for human space exploration, which strengthens the capability to extend human and robotic presence throughout the solar system. NASA is laying the groundwork to enable humans to safely reach multiple potential destinations, including asteroids, Lagrange points, the Moon and Mars. In support of this, NASA is embarking on the Technology Demonstration Mission Cryogenic Propellant Storage and Transfer (TDM CPST) Project to test and validate key cryogenic capabilities and technologies required for future exploration elements, opening up the architecture for large cryogenic propulsion stages (CPS) and propellant depots. The TDM CPST project will provide an on-orbit demonstration of the capability to store, transfer, and measure cryogenic propellants for a duration which is relevant to enable long term human space exploration missions beyond low Earth orbit (LEO). Recognizing that key cryogenic fluid management technologies anticipated for on-orbit (flight) demonstration needed to be matured to a readiness level appropriate for infusion into the design of the flight demonstration, the NASA Headquarters Space Technology Mission Directorate authorized funding for a one-year (FY12) ground based technology maturation program. The strategy, proposed by the CPST Project Manager, focused on maturation through modeling, studies, and ground tests of the storage and fluid transfer Cryogenic Fluid Management (CFM) technology sub-elements and components that were not already at a Technology Readiness Level (TRL) of 5. A technology maturation plan (TMP) was subsequently approved which described: the CFM technologies selected for maturation, the ground testing approach to be used, quantified success criteria of the technologies, hardware and data deliverables, and a deliverable to provide an assessment of the technology readiness after completion of the test, study or modeling activity. This paper will present

  9. Cryogenic Propellant Storage and Transfer (CPST) Technology Maturation: Establishing a Foundation for a Technology Demonstration Mission (TDM)

    NASA Technical Reports Server (NTRS)

    Doherty, Michael P.; Meyer, Michael L.; Motil, Susan M.; Ginty, Carol A.

    2013-01-01

    As part of U.S. National Space Policy, NASA is seeking an innovative path for human space exploration, which strengthens the capability to extend human and robotic presence throughout the solar system. NASA is laying the groundwork to enable humans to safely reach multiple potential destinations, including asteroids, Lagrange points, the Moon and Mars. In support of this, NASA is embarking on the Technology Demonstration Mission Cryogenic Propellant Storage and Transfer (TDM CPST) Project to test and validate key cryogenic capabilities and technologies required for future exploration elements, opening up the architecture for large cryogenic propulsion stages (CPS) and propellant depots. The TDM CPST project will provide an on-orbit demonstration of the capability to store, transfer, and measure cryogenic propellants for a duration which is relevant to enable long term human space exploration missions beyond low Earth orbit (LEO). Recognizing that key cryogenic fluid management technologies anticipated for on-orbit (flight) demonstration needed to be matured to a readiness level appropriate for infusion into the design of the flight demonstration, the NASA Headquarters Space Technology Mission Directorate authorized funding for a one-year (FY12) ground based technology maturation program. The strategy, proposed by the CPST Project Manager, focused on maturation through modeling, studies, and ground tests of the storage and fluid transfer Cryogenic Fluid Management (CFM) technology sub-elements and components that were not already at a Technology Readiness Level (TRL) of 5. A technology maturation plan (TMP) was subsequently approved which described: the CFM technologies selected for maturation, the ground testing approach to be used, quantified success criteria of the technologies, hardware and data deliverables, and a deliverable to provide an assessment of the technology readiness after completion of the test, study or modeling activity. This paper will present

  10. Towards G2G: Systems of Technology Database Systems

    NASA Technical Reports Server (NTRS)

    Maluf, David A.; Bell, David

    2005-01-01

    We present an approach and methodology for developing Government-to-Government (G2G) Systems of Technology Database Systems. G2G will deliver technologies for distributed and remote integration of technology data for internal use in analysis and planning as well as for external communications. G2G enables NASA managers, engineers, operational teams and information systems to "compose" technology roadmaps and plans by selecting, combining, extending, specializing and modifying components of technology database systems. G2G will interoperate information and knowledge that is distributed across organizational entities involved that is ideal for NASA future Exploration Enterprise. Key contributions of the G2G system will include the creation of an integrated approach to sustain effective management of technology investments that supports the ability of various technology database systems to be independently managed. The integration technology will comply with emerging open standards. Applications can thus be customized for local needs while enabling an integrated management of technology approach that serves the global needs of NASA. The G2G capabilities will use NASA s breakthrough in database "composition" and integration technology, will use and advance emerging open standards, and will use commercial information technologies to enable effective System of Technology Database systems.

  11. Technology Infusion Strategy: Beginning with a Pilot Project is the Key.

    ERIC Educational Resources Information Center

    Ball, John

    1996-01-01

    Presents an effective way to start a technological revolution in schools by beginning with a single exciting project that incorporates new technologies and then letting interest in the project prompt others to action. (JRH)

  12. Embedded 100 Gbps Photonic Components

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kuznia, Charlie

    This innovation to fiber optic component technology increases the performance, reduces the size and reduces the power consumption of optical communications within dense network systems, such as advanced distributed computing systems and data centers. VCSEL technology is enabling short-reach (< 100 m) and >100 Gbps optical interconnections over multi-mode fiber in commercial applications.

  13. A Tour of Big Data, Open Source Data Management Technologies from the Apache Software Foundation

    NASA Astrophysics Data System (ADS)

    Mattmann, C. A.

    2012-12-01

    The Apache Software Foundation, a non-profit foundation charged with dissemination of open source software for the public good, provides a suite of data management technologies for distributed archiving, data ingestion, data dissemination, processing, triage and a host of other functionalities that are becoming critical in the Big Data regime. Apache is the world's largest open source software organization, boasting over 3000 developers from around the world all contributing to some of the most pervasive technologies in use today, from the HTTPD web server that powers a majority of Internet web sites to the Hadoop technology that is now projected at over a $1B dollar industry. Apache data management technologies are emerging as de facto off-the-shelf components for searching, distributing, processing and archiving key science data sets both geophysical, space and planetary based, all the way to biomedicine. In this talk, I will give a virtual tour of the Apache Software Foundation, its meritocracy and governance structure, and also its key big data technologies that organizations can take advantage of today and use to save cost, schedule, and resources in implementing their Big Data needs. I'll illustrate the Apache technologies in the context of several national priority projects, including the U.S. National Climate Assessment (NCA), and in the International Square Kilometre Array (SKA) project that are stretching the boundaries of volume, velocity, complexity, and other key Big Data dimensions.

  14. The Digital Thread as the Key Enabler

    DTIC Science & Technology

    2016-11-01

    17 Defense AT&L: November-December 2016 The Digital Thread as the Key Enabler Col. Keith Bearden, USAF Bearden is the deputy director of...enabling you to do your job better, faster and cheaper. There is one initiative, the key enabler, to accomplish this goal—the digital thread . But let’s... process that would allow for rapid cross- domain analysis and technology transition prior to bending metal. • Re-establish a culture of “hands-on

  15. Security of Distributed-Phase-Reference Quantum Key Distribution

    NASA Astrophysics Data System (ADS)

    Moroder, Tobias; Curty, Marcos; Lim, Charles Ci Wen; Thinh, Le Phuc; Zbinden, Hugo; Gisin, Nicolas

    2012-12-01

    Distributed-phase-reference quantum key distribution stands out for its easy implementation with present day technology. For many years, a full security proof of these schemes in a realistic setting has been elusive. We solve this long-standing problem and present a generic method to prove the security of such protocols against general attacks. To illustrate our result, we provide lower bounds on the key generation rate of a variant of the coherent-one-way quantum key distribution protocol. In contrast to standard predictions, it appears to scale quadratically with the system transmittance.

  16. Structures Technology for Future Aerospace Systems

    NASA Technical Reports Server (NTRS)

    Noor, Ahmed K.; Venneri, Samuel L.; Paul, Donald B.; Hopkins, Mark A.

    2000-01-01

    An overview of structures technology for future aerospace systems is given. Discussion focuses on developments in component technologies that will improve the vehicle performance, advance the technology exploitation process, and reduce system life-cycle costs. The component technologies described are smart materials and structures, multifunctional materials and structures, affordable composite structures, extreme environment structures, flexible load bearing structures, and computational methods and simulation-based design. The trends in each of the component technologies are discussed and the applicability of these technologies to future aerospace vehicles is described.

  17. Development and Characterization of the Bonding and Integration Technologies Needed for Fabricating Silicon Carbide Based Injector Components

    NASA Technical Reports Server (NTRS)

    Halbig,Michael C.; Singh, Mrityunjay

    2008-01-01

    Advanced ceramic bonding and integration technologies play a critical role in the fabrication and application of silicon carbide based components for a number of aerospace and ground based applications. One such application is a lean direct injector for a turbine engine to achieve low NOx emissions. Ceramic to ceramic diffusion bonding and ceramic to metal brazing technologies are being developed for this injector application. For the diffusion bonding technology, titanium interlayers (coatings and foils) were used to aid in the joining of silicon carbide (SiC) substrates. The influence of such variables as surface finish, interlayer thickness, and processing time were investigated. Electron microprobe analysis was used to identify the reaction formed phases. In the diffusion bonds, an intermediate phase, Ti5Si3Cx, formed that is thermally incompatible in its thermal expansion and caused thermal stresses and cracking during the processing cool-down. Thinner interlayers of pure titanium and/or longer processing times resulted in an optimized microstructure. Tensile tests on the joined materials resulted in strengths of 13-28 MPa depending on the SiC substrate material. Nondestructive evaluation using ultrasonic immersion showed well formed bonds. For the joining technology of brazing Kovar fuel tubes to silicon carbide, preliminary development of the joining approach has begun. Various technical issues and requirements for the injector application are addressed.

  18. Identification of the Key Fields and Their Key Technical Points of Oncology by Patent Analysis.

    PubMed

    Zhang, Ting; Chen, Juan; Jia, Xiaofeng

    2015-01-01

    This paper aims to identify the key fields and their key technical points of oncology by patent analysis. Patents of oncology applied from 2006 to 2012 were searched in the Thomson Innovation database. The key fields and their key technical points were determined by analyzing the Derwent Classification (DC) and the International Patent Classification (IPC), respectively. Patent applications in the top ten DC occupied 80% of all the patent applications of oncology, which were the ten fields of oncology to be analyzed. The number of patent applications in these ten fields of oncology was standardized based on patent applications of oncology from 2006 to 2012. For each field, standardization was conducted separately for each of the seven years (2006-2012) and the mean of the seven standardized values was calculated to reflect the relative amount of patent applications in that field; meanwhile, regression analysis using time (year) and the standardized values of patent applications in seven years (2006-2012) was conducted so as to evaluate the trend of patent applications in each field. Two-dimensional quadrant analysis, together with the professional knowledge of oncology, was taken into consideration in determining the key fields of oncology. The fields located in the quadrant with high relative amount or increasing trend of patent applications are identified as key ones. By using the same method, the key technical points in each key field were identified. Altogether 116,820 patents of oncology applied from 2006 to 2012 were retrieved, and four key fields with twenty-nine key technical points were identified, including "natural products and polymers" with nine key technical points, "fermentation industry" with twelve ones, "electrical medical equipment" with four ones, and "diagnosis, surgery" with four ones. The results of this study could provide guidance on the development direction of oncology, and also help researchers broaden innovative ideas and discover new

  19. Application of UDWDM technology in FTTH networks

    NASA Astrophysics Data System (ADS)

    Lamperski, Jan; Stepczak, Piotr

    2015-12-01

    In the paper we presented results of investigation of an original ultra dense wavelength division technology based on optical comb generator and its implementation for FTTH networks. The optical comb generator used a ring configuration with an acousto-optic frequency shifter (AOFS) which ensured obtaining very stable optical carrier frequency distances. Properties of an optical comb generator module determined stability of the UDWDM transmitter. Key properties of a selective components based on all fiber Fabry-Perot resonant cavity were presented. Operation of direct and coherent detection DWDM systems were shown. New configurations of FTTH UDWDM architecture have been proposed.

  20. Multi-party Quantum Key Agreement without Entanglement

    NASA Astrophysics Data System (ADS)

    Cai, Bin-Bin; Guo, Gong-De; Lin, Song

    2017-04-01

    A new efficient quantum key agreement protocol without entanglement is proposed. In this protocol, each user encodes his secret key into the traveling particles by performing one of four rotation operations that one cannot perfectly distinguish. In the end, all users can simultaneously obtain the final shared key. The security of the presented protocol against some common attacks is discussed. It is shown that this protocol can effectively protect the privacy of each user and satisfy the requirement of fairness in theory. Moreover, the quantum carriers and the encoding operations used in the protocol can be achieved in realistic physical devices. Therefore, the presented protocol is feasible with current technology.

  1. Advanced ceramic matrix composite materials for current and future propulsion technology applications

    NASA Astrophysics Data System (ADS)

    Schmidt, S.; Beyer, S.; Knabe, H.; Immich, H.; Meistring, R.; Gessler, A.

    2004-08-01

    Current rocket engines, due to their method of construction, the materials used and the extreme loads to which they are subjected, feature a limited number of load cycles. Various technology programmes in Europe are concerned, besides developing reliable and rugged, low cost, throwaway equipment, with preparing for future reusable propulsion technologies. One of the key roles for realizing reusable engine components is the use of modern and innovative materials. One of the key technologies which concern various engine manufacturers worldwide is the development of fibre-reinforced ceramics—ceramic matrix composites. The advantages for the developers are obvious—the low specific weight, the high specific strength over a large temperature range, and their great damage tolerance compared to monolithic ceramics make this material class extremely interesting as a construction material. Over the past years, the Astrium company (formerly DASA) has, together with various partners, worked intensively on developing components for hypersonic engines and liquid rocket propulsion systems. In the year 2000, various hot-firing tests with subscale (scale 1:5) and full-scale nozzle extensions were conducted. In this year, a further decisive milestone was achieved in the sector of small thrusters, and long-term tests served to demonstrate the extraordinary stability of the C/SiC material. Besides developing and testing radiation-cooled nozzle components and small-thruster combustion chambers, Astrium worked on the preliminary development of actively cooled structures for future reusable propulsion systems. In order to get one step nearer to this objective, the development of a new fibre composite was commenced within the framework of a regionally sponsored programme. The objective here is to create multidirectional (3D) textile structures combined with a cost-effective infiltration process. Besides material and process development, the project also encompasses the development of

  2. Interprofessional collaboration within Canadian integrative healthcare clinics: Key components.

    PubMed

    Gaboury, Isabelle; Bujold, Mathieu; Boon, Heather; Moher, David

    2009-09-01

    Research shows that interprofessional collaboration has become an important factor in the implementation of effective healthcare models. To date, the literature has not focused on the collaboration between medical doctors and complementary and alternative medicine (CAM) healthcare practitioners, an example of interdisciplinary collaboration called integrative healthcare (IHC). Drawing on in-depth, semi-standardized interviews conducted with 21 practitioners working in Canadian IHC clinics, this paper explored and interpreted how IHC is experienced by those working in Canadian IHC clinics. The interview questions and analysis were guided by the Input, Process, Output conceptual framework drawn from the organizational management theory (McGrath, J. E. (1964). Social psychology: A brief introduction. New York: Holt, Rinehart and Winston.) to study collaboration within teams. We found that constructs contributing to collaboration included practitioners' attitudes and educational background, as well as external factors such as the healthcare system and financial pressures. Major processes affecting collaboration included communication, patient referral and power relationships. These determinants of collaboration were found to result in learning opportunities for practitioners, modified burden of work and ultimately, higher affective commitment toward the clinic. These constructs serve as a guide for further investigation of interprofessional collaboration within an IHC clinic. This exploration of interprofessional collaboration in IHC identified a broad array of key factors associated with interprofessional collaboration. These factors are critical to better understand the functioning of IHC clinics, and provide guidance for creation or maintenance of successful clinics.

  3. Industrial Arts Test Development, Book III. Resource Items for Graphics Technology, Power Technology, Production Technology.

    ERIC Educational Resources Information Center

    New York State Education Dept., Albany.

    This booklet is designed to assist teachers in developing examinations for classroom use. It is a collection of 955 objective test questions, mostly multiple choice, for industrial arts students in the three areas of graphics technology, power technology, and production technology. Scoring keys are provided. There are no copyright restrictions,…

  4. Design of virtual simulation experiment based on key events

    NASA Astrophysics Data System (ADS)

    Zhong, Zheng; Zhou, Dongbo; Song, Lingxiu

    2018-06-01

    Considering complex content and lacking of guidance in virtual simulation experiments, the key event technology in VR narrative theory was introduced for virtual simulation experiment to enhance fidelity and vividness process. Based on the VR narrative technology, an event transition structure was designed to meet the need of experimental operation process, and an interactive event processing model was used to generate key events in interactive scene. The experiment of" margin value of bees foraging" based on Biologic morphology was taken as an example, many objects, behaviors and other contents were reorganized. The result shows that this method can enhance the user's experience and ensure experimental process complete and effectively.

  5. Terrestrial Planet Finder: Technology Development Plans

    NASA Technical Reports Server (NTRS)

    Lindensmith, Chris

    2004-01-01

    One of humanity's oldest questions is whether life exists elsewhere in the universe. The Terrestrial Planet Finder (TPF) mission will survey stars in our stellar neighborhood to search for planets and perform spectroscopic measurements to identify potential biomarkers in their atmospheres. In response to the recently published President's Plan for Space Exploration, TPF has plans to launch a visible-light coronagraph in 2014, and a separated-spacecraft infrared interferometer in 2016. Substantial funding has been committed to the development of the key technologies that are required to meet these goals for launch in the next decade. Efforts underway through industry and university contracts and at JPL include a number of system and subsystem testbeds, as well as components and numerical modeling capabilities. The science, technology, and design efforts are closely coupled to ensure that requirements and capabilities will be consistent and meet the science goals.

  6. Residual stress evaluation of components produced via direct metal laser sintering

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kemerling, Brandon; Lippold, John C.; Fancher, Christopher M.

    Direct metal laser sintering is an additive manufacturing process which is capable of fabricating three-dimensional components using a laser energy source and metal powder particles. Despite the numerous benefits offered by this technology, the process maturity is low with respect to traditional subtractive manufacturing methods. Relationships between key processing parameters and final part properties are generally lacking and require further development. In this study, residual stresses were evaluated as a function of key process variables. The variables evaluated included laser scan strategy and build plate preheat temperature. Residual stresses were measured experimentally via neutron diffraction and computationally via finite elementmore » analysis. Good agreement was shown between the experimental and computational results. Results showed variations in the residual stress profile as a function of laser scan strategy. Compressive stresses were dominant along the build height (z) direction, and tensile stresses were dominant in the x and y directions. Build plate preheating was shown to be an effective method for alleviating residual stress due to the reduction in thermal gradient.« less

  7. Residual stress evaluation of components produced via direct metal laser sintering

    DOE PAGES

    Kemerling, Brandon; Lippold, John C.; Fancher, Christopher M.; ...

    2018-03-22

    Direct metal laser sintering is an additive manufacturing process which is capable of fabricating three-dimensional components using a laser energy source and metal powder particles. Despite the numerous benefits offered by this technology, the process maturity is low with respect to traditional subtractive manufacturing methods. Relationships between key processing parameters and final part properties are generally lacking and require further development. In this study, residual stresses were evaluated as a function of key process variables. The variables evaluated included laser scan strategy and build plate preheat temperature. Residual stresses were measured experimentally via neutron diffraction and computationally via finite elementmore » analysis. Good agreement was shown between the experimental and computational results. Results showed variations in the residual stress profile as a function of laser scan strategy. Compressive stresses were dominant along the build height (z) direction, and tensile stresses were dominant in the x and y directions. Build plate preheating was shown to be an effective method for alleviating residual stress due to the reduction in thermal gradient.« less

  8. Continuous-variable quantum authentication of physical unclonable keys

    NASA Astrophysics Data System (ADS)

    Nikolopoulos, Georgios M.; Diamanti, Eleni

    2017-04-01

    We propose a scheme for authentication of physical keys that are materialized by optical multiple-scattering media. The authentication relies on the optical response of the key when probed by randomly selected coherent states of light, and the use of standard wavefront-shaping techniques that direct the scattered photons coherently to a specific target mode at the output. The quadratures of the electromagnetic field of the scattered light at the target mode are analysed using a homodyne detection scheme, and the acceptance or rejection of the key is decided upon the outcomes of the measurements. The proposed scheme can be implemented with current technology and offers collision resistance and robustness against key cloning.

  9. Life prediction systems for critical rotating components

    NASA Technical Reports Server (NTRS)

    Cunningham, Susan E.

    1993-01-01

    With the advent of advanced materials in rotating gas turbine engine components, the methodologies for life prediction of these parts must also increase in sophistication and capability. Pratt & Whitney's view of generic requirements for composite component life prediction systems are presented, efforts underway to develop these systems are discussed, and industry participation in key areas requiring development is solicited.

  10. Determination of Key Flavor Components in Methylene Chloride Extracts from Processed Grapefruit Juice.

    PubMed

    Jella; Rouseff; Goodner; Widmer

    1998-01-19

    The relative correlation of 52 aroma and 5 taste components in commercial not-from-concentrate grapefruit juices with flavor panel preference was determined. Methylene chloride extracts of juice were analyzed using GC/MS with a DB-5 column. Nonvolatiles determined included limonin and naringin by HPLC, degrees Brix, total acids, and degrees Brix/acid ratio. Juice samples were classified into low, medium, or high categories, based on average taste panel preference scores (nine-point hedonic scale). Principal component analysis demonstrated that highest quality juices were tightly clustered. Discriminant analysis indicated that 82% of the samples could be identified in the correct preference category using only myrcene, beta-caryophyllene, linalool, nootkatone, and degrees Brix. Nootkatone alone was not strongly associated with preference scores. The most preferred juices were strongly associated with low myrcene, low linalool, and intermediate levels of beta-caryophyllene.

  11. Public perceptions of key performance indicators of healthcare in Alberta, Canada.

    PubMed

    Northcott, Herbert C; Harvey, Michael D

    2012-06-01

    To examine the relationship between public perceptions of key performance indicators assessing various aspects of the health-care system. Cross-sequential survey research. Annual telephone surveys of random samples of adult Albertans selected by random digit dialing and stratified according to age, sex and region (n = 4000 for each survey year). The survey questionnaires included single-item measures of key performance indicators to assess public perceptions of availability, accessibility, quality, outcome and satisfaction with healthcare. Cronbach's α and factor analysis were used to assess the relationship between key performance indicators focusing on the health-care system overall and on a recent interaction with the health-care system. The province of Alberta, Canada during the years 1996-2004. Four thousand adults randomly selected each survey year. Survey questions measuring public perceptions of healthcare availability, accessibility, quality, outcome and satisfaction with healthcare. Factor analysis identified two principal components with key performance indicators focusing on the health system overall loading most strongly on the first component and key performance indicators focusing on the most recent health-care encounter loading most strongly on the second component. Assessments of the quality of care most recently received, accessibility of that care and perceived outcome of care tended to be higher than the more general assessments of overall health system quality and accessibility. Assessments of specific health-care encounters and more general assessments of the overall health-care system, while related, nevertheless comprise separate dimensions for health-care evaluation.

  12. The NASA Advanced Communications Technology Satellite (ACTS)

    NASA Astrophysics Data System (ADS)

    Beck, G. A.

    1984-10-01

    Forecasts indicate that a saturation of the capacity of the satellite communications service will occur in the U.S. domestic market by the early 1990s. In order to prevent this from happening, advanced technologies must be developed. NASA has been concerned with such a development. One key is the exploitation of the Ka-band (30/20 GHz), which is much wider than C- and Ku-bands together. Another is the use of multiple narrow antenna beams in the satellite to achieve large frequency reuse factors with very high antenna gains. NASA has developed proof-of-concept hardware components which form the basis for a flight demonstration. The Advanced Communications Technology Satellite (ACTS) system will provide this demonstration. Attention is given to the ACTS Program definition, the ACTS Flight System, the Multibeam Communications Package, and the spacecraft bus.

  13. Improved components for engine fuel savings

    NASA Technical Reports Server (NTRS)

    Antl, R. J.; Mcaulay, J. E.

    1980-01-01

    NASA programs for developing fuel saving technology include the Engine Component Improvement Project for short term improvements in existing air engines. The Performance Improvement section is to define component technologies for improving fuel efficiency for CF6, JT9D and JT8D turbofan engines. Sixteen concepts were developed and nine were tested while four are already in use by airlines. If all sixteen concepts are successfully introduced the gain will be fuel savings of more than 6 billion gallons over the lifetime of the engines. The improvements include modifications in fans, mounts, exhaust nozzles, turbine clearance and turbine blades.

  14. Stakeholders perspectives on the key components of community-based interventions coordinating care in dementia: a qualitative systematic review.

    PubMed

    Backhouse, Amy; Richards, David A; McCabe, Rose; Watkins, Ross; Dickens, Chris

    2017-11-22

    Interventions aiming to coordinate services for the community-based dementia population vary in components, organisation and implementation. In this review we aimed to investigate the views of stakeholders on the key components of community-based interventions coordinating care in dementia. We searched four databases from inception to June 2015; Medline, The Cochrane Library, EMBASE and PsycINFO, this was aided by a search of four grey literature databases, and backward and forward citation tracking of included papers. Title and abstract screening was followed by a full text screen by two independent reviewers, and quality was assessed using the CASP appraisal tool. We then conducted thematic synthesis on extracted data. A total of seven papers from five independent studies were included in the review, and encompassed the views of over 100 participants from three countries. Through thematic synthesis we identified 32 initial codes that were grouped into 5 second-order themes: (1) case manager had four associated codes and described preferences for the case manager personal and professional attributes, including a sound knowledge in dementia and availability of local services; (2) communication had five associated codes and emphasized the importance stakeholders placed on multichannel communication with service users, as well as between multidisciplinary teams and across organisations; (3) intervention had 11 associated codes which focused primarily on the practicalities of implementation such as the contact type and frequency between case managers and service users, and the importance of case manager training and service evaluation; (4) resources had five associated codes which outlined stakeholder views on the required resources for coordinating interventions and potential overlap with existing resources, as well as arising issues when available resources do not meet those required for successful implementation; and (5) support had seven associated codes that

  15. Research Technology

    NASA Image and Video Library

    2002-08-01

    An array of components in a laboratory at NASA's Marshall Space Flight Center (MSFC) is being tested by the Flight Mechanics Office to develop an integrated navigation system for the second generation reusable launch vehicle. The laboratory is testing Global Positioning System (GPS) components, a satellite-based location and navigation system, and Inertial Navigation System (INS) components, sensors on a vehicle that determine angular velocity and linear acceleration at various points. The GPS and INS components work together to provide a space vehicle with guidance and navigation, like the push of the OnStar button in your car assists you with directions to a specific address. The integration will enable the vehicle operating system to track where the vehicle is in space and define its trajectory. The use of INS components for navigation is not new to space technology. The Space Shuttle currently uses them. However, the Space Launch Initiative is expanding the technology to integrate GPS and INS components to allow the vehicle to better define its position and more accurately determine vehicle acceleration and velocity. This advanced technology will lower operational costs and enhance the safety of reusable launch vehicles by providing a more comprehensive navigation system with greater capabilities. In this photograph, Dr. Jason Chuang of MSFC inspects an INS component in the laboratory.

  16. The Technological Personality

    ERIC Educational Resources Information Center

    Stivers, Richard

    2004-01-01

    If technology is the single most important factor in explaining the organization of modern societies, it is likewise the key to understanding the modern personality. The technological personality is the psychological counterpart to the technological society.Technology indirectly destroys the basis of a common morality and so leaves human…

  17. Keys to the Adoption and Use of Voice Recognition Technology in Organizations.

    ERIC Educational Resources Information Center

    Goette, Tanya

    2000-01-01

    Presents results from a field study of individuals with disabilities who used voice recognition technology (VRT). Results indicated that task-technology fit, training, the environment, and disability limitations were the differentiating items, and that using VRT for a trial period may be the major factor in successful adoption of the technology.…

  18. Changing Technology and Work: Northern Telecom. CAW Technology Project.

    ERIC Educational Resources Information Center

    Robertson, David; Wareham, Jeff

    A project to examine the implications of technological change at Northern Telecom consisted of two major components: a technological survey and case study research. A questionnaire that contained more than 90 questions on technological change was distributed through local union technology committee meetings in Brampton, London, Belleville, and…

  19. Technology-enhanced focus groups as a component of instrument development.

    PubMed

    Strout, Tania D; DiFazio, Rachel L; Vessey, Judith A

    2017-06-22

    Background Bullying is a critical public health problem and a screening tool for use in healthcare is needed. Focus groups are a common tool for generating qualitative data when developing an instrument and evidence suggests that technology-enhanced focus groups can be effective in simultaneously engaging participants from diverse settings. Aim To examine the use of technology-enhanced focus groups in generating an item pool to develop a youth-bullying screening tool. Discussion The authors explore methodological and ethical issues related to conducting technology-enhanced focus groups, drawing on their experience in developing a youth-bullying measure. They conducted qualitative focus groups with professionals from the front lines of bullying response and intervention. They describe the experience of conducting technology-enhanced focus group sessions, focusing on the methodological and ethical issues that researchers engaging in similar work may encounter. Challenges associated with this methodology include establishing rapport among participants, privacy concerns and limited non-verbal communication. Conclusion The use of technology-enhanced focus groups can be valuable in obtaining rich data from a wide variety of disciplines and contexts. Organising these focus groups was inexpensive and preferred by the study's participants. Implications for practice Researchers should consider using technology-enhanced focus groups to generate data to develop health-related measurement tools.

  20. Current Research Activities in Drive System Technology in Support of the NASA Rotorcraft Program

    NASA Technical Reports Server (NTRS)

    Handschuh, Robert F.; Zakrajsek, James J.

    2006-01-01

    Drive system technology is a key area for improving rotorcraft performance, noise/vibration reduction, and reducing operational and manufacturing costs. An overview of current research areas that support the NASA Rotorcraft Program will be provided. Work in drive system technology is mainly focused within three research areas: advanced components, thermal behavior/emergency lubrication system operation, and diagnostics/prognostics (also known as Health and Usage Monitoring Systems (HUMS)). Current research activities in each of these activities will be presented. Also, an overview of the conceptual drive system requirements and possible arrangements for the Heavy Lift Rotorcraft program will be reviewed.

  1. Health-Enabling and Ambient Assistive Technologies: Past, Present, Future.

    PubMed

    Haux, R; Koch, S; Lovell, N H; Marschollek, M; Nakashima, N; Wolf, K-H

    2016-06-30

    During the last decades, health-enabling and ambient assistive technologies became of considerable relevance for new informatics-based forms of diagnosis, prevention, and therapy. To describe the state of the art of health-enabling and ambient assistive technologies in 1992 and today, and its evolution over the last 25 years as well as to project where the field is expected to be in the next 25 years. In the context of this review, we define health-enabling and ambient assistive technologies as ambiently used sensor-based information and communication technologies, aiming at contributing to a person's health and health care as well as to her or his quality of life. Systematic review of all original articles with research focus in all volumes of the IMIA Yearbook of Medical Informatics. Surveying authors independently on key projects and visions as well as on their lessons learned in the context of health-enabling and ambient assistive technologies and summarizing their answers. Surveying authors independently on their expectations for the future and summarizing their answers. IMIA Yearbook papers containing statements on health-enabling and ambient assistive technologies appear first in 2002. These papers form a minor part of published research articles in medical informatics. However, during recent years the number of articles published has increased significantly. Key projects were identified. There was a clear progress on the use of technologies. However proof of diagnostic relevance and therapeutic efficacy remains still limited. Reforming health care processes and focussing more on patient needs are required. Health-enabling and ambient assistive technologies remain an important field for future health care and for interdisciplinary research. More and more publications assume that a person's home and their interaction therein, are becoming important components in health care provision, assessment, and management.

  2. Health-Enabling and Ambient Assistive Technologies: Past, Present, Future

    PubMed Central

    2016-01-01

    Summary Background During the last decades, health-enabling and ambient assistive technologies became of considerable relevance for new informatics-based forms of diagnosis, prevention, and therapy. Objectives To describe the state of the art of health-enabling and ambient assistive technologies in 1992 and today, and its evolution over the last 25 years as well as to project where the field is expected to be in the next 25 years. In the context of this review, we define health-enabling and ambient assistive technologies as ambiently used sensor-based information and communication technologies, aiming at contributing to a person’s health and health care as well as to her or his quality of life. Methods Systematic review of all original articles with research focus in all volumes of the IMIA Yearbook of Medical Informatics. Surveying authors independently on key projects and visions as well as on their lessons learned in the context of health-enabling and ambient assistive technologies and summarizing their answers. Surveying authors independently on their expectations for the future and summarizing their answers. Results IMIA Yearbook papers containing statements on health-enabling and ambient assistive technologies appear first in 2002. These papers form a minor part of published research articles in medical informatics. However, during recent years the number of articles published has increased significantly. Key projects were identified. There was a clear progress on the use of technologies. However proof of diagnostic relevance and therapeutic efficacy remains still limited. Reforming health care processes and focussing more on patient needs are required. Conclusions Health-enabling and ambient assistive technologies remain an important field for future health care and for interdisciplinary research. More and more publications assume that a person‘s home and their interaction therein, are becoming important components in health care provision, assessment

  3. Using a computer-based simulation with an artificial intelligence component and discovery learning to formulate training needs for a new technology

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hillis, D.R.

    A computer-based simulation with an artificial intelligence component and discovery learning was investigated as a method to formulate training needs for new or unfamiliar technologies. Specifically, the study examined if this simulation method would provide for the recognition of applications and knowledge/skills which would be the basis for establishing training needs. The study also examined the effect of field-dependence/independence on recognition of applications and knowledge/skills. A pretest-posttest control group experimental design involving fifty-eight college students from an industrial technology program was used. The study concluded that the simulation was effective in developing recognition of applications and the knowledge/skills for amore » new or unfamiliar technology. And, the simulation's effectiveness for providing this recognition was not limited by an individual's field-dependence/independence.« less

  4. Sizing Power Components of an Electrically Driven Tail Cone Thruster and a Range Extender

    NASA Technical Reports Server (NTRS)

    Jansen, Ralph H.; Bowman, Cheryl; Jankovsky, Amy

    2016-01-01

    The aeronautics industry has been challenged on many fronts to increase efficiency, reduce emissions, and decrease dependency on carbon-based fuels. The NASA Aeronautics Research Mission Directorate has identified a suite of investments to meet long term research demands beyond the purview of commercial investment. Electrification of aviation propulsion through turboelectric or hybrid electric propulsion is one of many exciting research areas which has the potential to revolutionize the aviation industry. This paper will provide an overview of the turboelectric and hybrid electric technologies being developed under NASAs Advanced Air Transportation Technology (AATT) Project, and how these technologies can impact vehicle design. An overview will be presented of vehicle system studies and the electric drive system assumptions for successful turboelectric and hybrid electric propulsion in single aisle size commercial aircraft. Key performance parameters for electric drive system technologies will be reviewed, and the technical investment made in materials, electric machines, power electronics, and integrated power systems will be discussed. Finally, power components for a single aisle turboelectric aircraft with an electrically driven tail cone thruster and a hybrid electric nine passenger aircraft with a range extender will be parametrically sized.

  5. EAGLE: relay mirror technology development

    NASA Astrophysics Data System (ADS)

    Hartman, Mary; Restaino, Sergio R.; Baker, Jeffrey T.; Payne, Don M.; Bukley, Jerry W.

    2002-06-01

    EAGLE (Evolutionary Air & Space Global Laser Engagement) is the proposed high power weapon system with a high power laser source, a relay mirror constellation, and the necessary ground and communications links. The relay mirror itself will be a satellite composed of two optically-coupled telescopes/mirrors used to redirect laser energy from ground, air, or space based laser sources to distant points on the earth or space. The receiver telescope captures the incoming energy, relays it through an optical system that cleans up the beam, then a separate transmitter telescope/mirror redirects the laser energy at the desired target. Not only is it a key component in extending the range of DoD's current laser weapon systems, it also enables ancillary missions. Furthermore, if the vacuum of space is utilized, then the atmospheric effects on the laser beam propagation will be greatly attenuated. Finally, several critical technologies are being developed to make the EAGLE/Relay Mirror concept a reality, and the Relay Mirror Technology Development Program was set up to address them. This paper will discuss each critical technology, the current state of the work, and the future implications of this program.

  6. 2006 Precision Strike Technology Symposium

    DTIC Science & Technology

    2006-10-19

    s Navy Unique Joint system 14 A/C Unique Components Framework JMPS Common Components Crypto Key GCCS-M Interface Carrier Intel Feed Carrier...210 GPS Prediction CUPC GPS Crypto Key TAMMAC SLAM-ER GPS Almanac ETIRMS PMA-281 NGMS PMA-209 Boeing PMA-201 Raytheon ESC (USAF) Hill AFB PMA-234 PMA...242 F/A-18 UPC GPS Prediction CUPC GPS Crypto Key TAMMAC SLAM-ER GPS Almanac HARM WASP Framework ARC-210 ETIRMS PMA-281 Integration/Test/ Support TLAM

  7. Reusable launch vehicle: Technology development and test program

    NASA Technical Reports Server (NTRS)

    1995-01-01

    The National Aeronautics and Space Administration (NASA) requested that the National Research Council (NRC) assess the Reusable Launch Vehicle (RLV) technology development and test programs in the most critical component technologies. At a time when discretionary government spending is under close scrutiny, the RLV program is designed to reduce the cost of access to space through a combination of robust vehicles and a streamlined infrastructure. Routine access to space has obvious benefits for space science, national security, commercial technologies, and the further exploration of space. Because of technological challenges, knowledgeable people disagree about the feasibility of a single-stage-to-orbit (SSTO) vehicle. The purpose of the RLV program proposed by NASA and industry contractors is to investigate the status of existing technology and to identify and advance key technology areas required for development and validation of an SSTO vehicle. This report does not address the feasibility of an SSTO vehicle, nor does it revisit the roles and responsibilities assigned to NASA by the National Transportation Policy. Instead, the report sets forth the NRC committee's findings and recommendations regarding the RLV technology development and test program in the critical areas of propulsion, a reusable cryogenic tank system (RCTS), primary vehicle structure, and a thermal protection system (TPS).

  8. Components for IFOG based inertial measurement units using active and passive polymer materials

    NASA Astrophysics Data System (ADS)

    Ashley, Paul R.; Temmen, Mark G.; Diffey, William M.; Sanghadasa, Mohan; Bramson, Michael D.; Lindsay, Geoffrey A.; Guenthner, Andrew J.

    2006-08-01

    Highly accurate, compact, and low cost inertial measurement units (IMUs) are needed for precision guidance in navigation systems. Active and passive polymer materials have been successfully used in fabricating two of the key guided-wave components, the phase modulator and the optical transceiver, for IMUs based on the interferometric fiber optic gyroscope (IFOG) technology. Advanced hybrid waveguide fabrication processes and novel optical integration techniques have been introduced. Backscatter compensated low loss phase modulators with low half-wave drive voltage (V π) have been fabricated with CLD- and FTC- type high performance electro-optic chromophores. A silicon-bench architecture has been used in fabricating high gain low noise transceivers with high optical power while maintaining the spectral quality and long lifetime. Gyro bias stability of less than 0.02 deg/hr has been demonstrated with these components. A review of the novel concepts introduced, fabrication and integration techniques developed and performance achieved are presented.

  9. USCA, a codeveloped piece of technology, is presented to Bridges, KSC Director, by Saputo, L-3 Commu

    NASA Technical Reports Server (NTRS)

    1997-01-01

    William Saputo, L-3 Communications, presents a new piece of technology, developed through a National Aeronautics and Space Administration (NASA) partnership with industry, to Kennedy Space Center (KSC) Director Roy Bridges, Jr. (second from left). The piece of technology being presented, the Universal Signal Conditioning Amplifier (USCA), is a key component of the codeveloped Automated Data Acquisition System (ADAS) that measures temperature, pressure and vibration at KSC's launch pads. The breakthrough technology is expected to reduce sensor setup and configuration times from hours to seconds. KSC teamed up with Florida's Technological Research and Development Authority and manufacturer L-3 Communications to produce a system that would benefit the aerospace industry and other commercial markets.

  10. NCAP projection displays: key issues for commercialization

    NASA Astrophysics Data System (ADS)

    Tomita, Akira; Jones, Philip J.

    1992-06-01

    Recently there has been much interest in a new polymer nematic dispersion technology, often called as NCAP, PDLC, PNLC, LCPC, etc., since projection displays using this technology have been shown to produce much brighter display images than projectors using conventional twisted nematic (TN) lightvalves. For commercializing projection displays based on this polymer nematic dispersion technology, the new materials must not only meet various electro- optic requirements, e.g., operational voltage, `off-state'' scattering angle, voltage holding ratio and hysteresis, but must also be stable over the lifetime of the product. This paper reports recent progress in the development of NCAP based projection displays and discusses some of the key commercialization issues.

  11. Sustainable health systems: addressing three key areas.

    PubMed

    Chhanabhai, Prajesh N; Holt, Alec; Benwell, George

    2007-01-01

    In the modern context sustainable health systems are being developed using the newest technological and communication technologies. This is proving to be a great success for the growth of Health Informatics and healthcare improvement. However this revolution is not being reached by a lot of the world population. This paper will address the importance of closing the Digital Divide, Empowerment of health consumers and the importance of converging communications. Key areas in the development of a truly sustainable health system.

  12. Developing a Strategic Program for Chilean Health Information Technology: Environmental Scan and Key Informant Interviews.

    PubMed

    Taylor, Erin Audrey; Fischer, Shira H; Gracner, Tadeja; Tejeda, Ivo; Kim, Alice; Chavez-Herrerias, Emilio; de la Guardia, Fernando Hoces

    2016-06-20

    As part of an effort to assist Chile in developing a strategic program to foster the development of the health information technology (health IT) sector over the next five to ten years, this study assesses the current state of health IT adoption and implementation in Chile, as well as the challenges and opportunities facing the sector over the coming years. The authors conducted an environmental scan and ten key informant interviews and found that there are a number of successful health IT projects and strategies for further development currently underway in Chile, but that the successful projects are generally localized within specific health care providers and lack integration. These and other challenges suggest significant potential for the Ministry of Economy and other stakeholders to take specific actions designed to encourage further development of the health IT sector in Chile over the coming years. The next phase of this effort will use the results from this study to develop a roadmap for the Ministry of Economy to encourage health IT development in Chile over the short, medium, and long terms.

  13. Escherichia Coli--Key to Modern Genetics.

    ERIC Educational Resources Information Center

    Bregegere, Francois

    1982-01-01

    Mid-nineteenth century work by Mendel on plant hybrids and by Pasteur on fermentation gave birth by way of bacterial genetics to modern-day molecular biology. The bacterium Escherichia Coli has occupied a key position in genetic studies leading from early gene identification with DNA to current genetic engineering using recombinant DNA technology.…

  14. Identification of the Key Fields and Their Key Technical Points of Oncology by Patent Analysis

    PubMed Central

    Zhang, Ting; Chen, Juan; Jia, Xiaofeng

    2015-01-01

    Background This paper aims to identify the key fields and their key technical points of oncology by patent analysis. Methodology/Principal Findings Patents of oncology applied from 2006 to 2012 were searched in the Thomson Innovation database. The key fields and their key technical points were determined by analyzing the Derwent Classification (DC) and the International Patent Classification (IPC), respectively. Patent applications in the top ten DC occupied 80% of all the patent applications of oncology, which were the ten fields of oncology to be analyzed. The number of patent applications in these ten fields of oncology was standardized based on patent applications of oncology from 2006 to 2012. For each field, standardization was conducted separately for each of the seven years (2006–2012) and the mean of the seven standardized values was calculated to reflect the relative amount of patent applications in that field; meanwhile, regression analysis using time (year) and the standardized values of patent applications in seven years (2006–2012) was conducted so as to evaluate the trend of patent applications in each field. Two-dimensional quadrant analysis, together with the professional knowledge of oncology, was taken into consideration in determining the key fields of oncology. The fields located in the quadrant with high relative amount or increasing trend of patent applications are identified as key ones. By using the same method, the key technical points in each key field were identified. Altogether 116,820 patents of oncology applied from 2006 to 2012 were retrieved, and four key fields with twenty-nine key technical points were identified, including “natural products and polymers” with nine key technical points, “fermentation industry” with twelve ones, “electrical medical equipment” with four ones, and “diagnosis, surgery” with four ones. Conclusions/Significance The results of this study could provide guidance on the development

  15. Research on the key technology of update of land survey spatial data based on embedded GIS and GPS

    NASA Astrophysics Data System (ADS)

    Chen, Dan; Liu, Yanfang; Yu, Hai; Xia, Yin

    2009-10-01

    According to the actual needs of the second land-use survey and the PDA's characteristics of small volume and small memory, it can be analyzed that the key technology of the data collection system of field survey based on GPS-PDA is the read speed of the data. In order to enhance the speed and efficiency of the analysis of the spatial data on mobile devices, we classify the layers of spatial data; get the Layer-Grid Index by getting the different levels and blocks of the layer of spatial data; then get the R-TREE index of the spatial data objects. Different scale levels of space are used in different levels management. The grid method is used to do the block management.

  16. Shape optimization of tibial prosthesis components

    NASA Technical Reports Server (NTRS)

    Saravanos, D. A.; Mraz, P. J.; Davy, D. T.

    1993-01-01

    NASA technology and optimal design methodologies originally developed for the optimization of composite structures (engine blades) are adapted and applied to the optimization of orthopaedic knee implants. A method is developed enabling the shape tailoring of the tibial components of a total knee replacement implant for optimal interaction within the environment of the tibia. The shape of the implant components are optimized such that the stresses in the bone are favorably controlled to minimize bone degradation, to improve the mechanical integrity of the implant/interface/bone system, and to prevent failures of the implant components. A pilot tailoring system is developed and the feasibility of the concept is demonstrated and evaluated. The methodology and evolution of the existing aerospace technology from which this pilot optimization code was developed is also presented and discussed. Both symmetric and unsymmetric in-plane loading conditions are investigated. The results of the optimization process indicate a trend toward wider and tapered posts as well as thicker backing trays. Unique component geometries were obtained for the different load cases.

  17. Quantum key distribution without detector vulnerabilities using optically seeded lasers

    NASA Astrophysics Data System (ADS)

    Comandar, L. C.; Lucamarini, M.; Fröhlich, B.; Dynes, J. F.; Sharpe, A. W.; Tam, S. W.-B.; Yuan, Z. L.; Penty, R. V.; Shields, A. J.

    2016-05-01

    Security in quantum cryptography is continuously challenged by inventive attacks targeting the real components of a cryptographic set-up, and duly restored by new countermeasures to foil them. Owing to their high sensitivity and complex design, detectors are the most frequently attacked components. It was recently shown that two-photon interference from independent light sources can be used to remove any vulnerability from detectors. This new form of detection-safe quantum key distribution (QKD), termed measurement-device-independent (MDI), has been experimentally demonstrated but with modest key rates. Here, we introduce a new pulsed laser seeding technique to obtain high-visibility interference from gain-switched lasers and thereby perform MDI-QKD with unprecedented key rates in excess of 1 megabit per second in the finite-size regime. This represents a two to six orders of magnitude improvement over existing implementations and supports the new scheme as a practical resource for secure quantum communications.

  18. Smart sensor technology for advanced launch vehicles

    NASA Astrophysics Data System (ADS)

    Schoess, Jeff

    1989-07-01

    Next-generation advanced launch vehicles will require improved use of sensor data and the management of multisensor resources to achieve automated preflight checkout, prelaunch readiness assessment and vehicle inflight condition monitoring. Smart sensor technology is a key component in meeting these needs. This paper describes the development of a smart sensor-based condition monitoring system concept referred to as the Distributed Sensor Architecture. A significant event and anomaly detection scheme that provides real-time condition assessment and fault diagnosis of advanced launch system rocket engines is described. The design and flight test of a smart autonomous sensor for Space Shuttle structural integrity health monitoring is presented.

  19. Laser beam soldering of micro-optical components

    NASA Astrophysics Data System (ADS)

    Eberhardt, R.

    2003-05-01

    MOTIVATION Ongoing miniaturisation and higher requirements within optical assemblies and the processing of temperature sensitive components demands for innovative selective joining techniques. So far adhesive bonding has primarily been used to assemble and adjust hybrid micro optical systems. However, the properties of the organic polymers used for the adhesives limit the application of these systems. In fields of telecommunication and lithography, an enhancement of existing joining techniques is necessary to improve properties like humidity resistance, laserstability, UV-stability, thermal cycle reliability and life time reliability. Against this background laser beam soldering of optical components is a reasonable joining technology alternative. Properties like: - time and area restricted energy input - energy input can be controlled by the process temperature - direct and indirect heating of the components is possible - no mechanical contact between joining tool and components give good conditions to meet the requirements on a joining technology for sensitive optical components. Additionally to the laser soldering head, for the assembly of optical components it is necessary to include positioning units to adjust the position of the components with high accuracy before joining. Furthermore, suitable measurement methods to characterize the soldered assemblies (for instance in terms of position tolerances) need to be developed.

  20. Electrical and electronic devices and components: A compilation

    NASA Technical Reports Server (NTRS)

    1975-01-01

    Components and techniques which may be useful in the electronics industry are described. Topics discussed include transducer technology, printed-circuit technology, solid state devices, MOS transistors, Gunn device, microwave antennas, and position indicators.

  1. A Wafer Transfer Technology for MEMS Adaptive Optics

    NASA Technical Reports Server (NTRS)

    Yang, Eui-Hyeok; Wiberg, Dean V.

    2001-01-01

    Adaptive optics systems require the combination of several advanced technologies such as precision optics, wavefront sensors, deformable mirrors, and lasers with high-speed control systems. The deformable mirror with a continuous membrane is a key component of these systems. This paper describes a new technique for transferring an entire wafer-level silicon membrane from one substrate to another. This technology is developed for the fabrication of a compact deformable mirror with a continuous facet. A 1 (mu)m thick silicon membrane, 100 mm in diameter, has been successfully transferred without using adhesives or polymers (i.e. wax, epoxy, or photoresist). Smaller or larger diameter membranes can also be transferred using this technique. The fabricated actuator membrane with an electrode gap of 1.5 (mu)m shows a vertical deflection of 0.37 (mu)m at 55 V.

  2. The SECOQC quantum key distribution network in Vienna

    NASA Astrophysics Data System (ADS)

    Peev, M.; Pacher, C.; Alléaume, R.; Barreiro, C.; Bouda, J.; Boxleitner, W.; Debuisschert, T.; Diamanti, E.; Dianati, M.; Dynes, J. F.; Fasel, S.; Fossier, S.; Fürst, M.; Gautier, J.-D.; Gay, O.; Gisin, N.; Grangier, P.; Happe, A.; Hasani, Y.; Hentschel, M.; Hübel, H.; Humer, G.; Länger, T.; Legré, M.; Lieger, R.; Lodewyck, J.; Lorünser, T.; Lütkenhaus, N.; Marhold, A.; Matyus, T.; Maurhart, O.; Monat, L.; Nauerth, S.; Page, J.-B.; Poppe, A.; Querasser, E.; Ribordy, G.; Robyr, S.; Salvail, L.; Sharpe, A. W.; Shields, A. J.; Stucki, D.; Suda, M.; Tamas, C.; Themel, T.; Thew, R. T.; Thoma, Y.; Treiber, A.; Trinkler, P.; Tualle-Brouri, R.; Vannel, F.; Walenta, N.; Weier, H.; Weinfurter, H.; Wimberger, I.; Yuan, Z. L.; Zbinden, H.; Zeilinger, A.

    2009-07-01

    In this paper, we present the quantum key distribution (QKD) network designed and implemented by the European project SEcure COmmunication based on Quantum Cryptography (SECOQC) (2004-2008), unifying the efforts of 41 research and industrial organizations. The paper summarizes the SECOQC approach to QKD networks with a focus on the trusted repeater paradigm. It discusses the architecture and functionality of the SECOQC trusted repeater prototype, which has been put into operation in Vienna in 2008 and publicly demonstrated in the framework of a SECOQC QKD conference held from October 8 to 10, 2008. The demonstration involved one-time pad encrypted telephone communication, a secure (AES encryption protected) video-conference with all deployed nodes and a number of rerouting experiments, highlighting basic mechanisms of the SECOQC network functionality. The paper gives an overview of the eight point-to-point network links in the prototype and their underlying technology: three plug and play systems by id Quantique, a one way weak pulse system from Toshiba Research in the UK, a coherent one-way system by GAP Optique with the participation of id Quantique and the AIT Austrian Institute of Technology (formerly ARCAustrian Research Centers GmbH—ARC is now operating under the new name AIT Austrian Institute of Technology GmbH following a restructuring initiative.), an entangled photons system by the University of Vienna and the AIT, a continuous-variables system by Centre National de la Recherche Scientifique (CNRS) and THALES Research and Technology with the participation of Université Libre de Bruxelles, and a free space link by the Ludwig Maximillians University in Munich connecting two nodes situated in adjacent buildings (line of sight 80 m). The average link length is between 20 and 30 km, the longest link being 83 km. The paper presents the architecture and functionality of the principal networking agent—the SECOQC node module, which enables the authentic

  3. Entrepreneurship. Technology Learning Activity. Teacher Edition. Technology Education Series.

    ERIC Educational Resources Information Center

    Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

    This packet of technology learning activity (TLA) materials on entrepreneurship for students in grades 6-10 consists of a technology education overview, information on use, and instructor's and student's sections. The overview discusses the technology education program and materials. Components of the instructor's and student's sections are…

  4. Identification of high performance and component technology for space electrical power systems for use beyond the year 2000

    NASA Technical Reports Server (NTRS)

    Maisel, James E.

    1988-01-01

    Addressed are some of the space electrical power system technologies that should be developed for the U.S. space program to remain competitive in the 21st century. A brief historical overview of some U.S. manned/unmanned spacecraft power systems is discussed to establish the fact that electrical systems are and will continue to become more sophisticated as the power levels appoach those on the ground. Adaptive/Expert power systems that can function in an extraterrestrial environment will be required to take an appropriate action during electrical faults so that the impact is minimal. Manhours can be reduced significantly by relinquishing tedious routine system component maintenance to the adaptive/expert system. By cataloging component signatures over time this system can set a flag for a premature component failure and thus possibly avoid a major fault. High frequency operation is important if the electrical power system mass is to be cut significantly. High power semiconductor or vacuum switching components will be required to meet future power demands. System mass tradeoffs have been investigated in terms of operating at high temperature, efficiency, voltage regulation, and system reliability. High temperature semiconductors will be required. Silicon carbide materials will operate at a temperature around 1000 K and the diamond material up to 1300 K. The driver for elevated temperature operation is that radiator mass is reduced significantly because of inverse temperature to the fourth power.

  5. Technology Challenges for Deep-Throttle Cryogenic Engines for Space Exploration

    NASA Technical Reports Server (NTRS)

    Brown, Kendall K.; Nelson, Karl W.

    2005-01-01

    Historically, cryogenic rocket engines have not been used for in-space applications due to their additional complexity, the mission need for high reliability, and the challenges of propellant boil-off. While the mission and vehicle architectures are not yet defined for the lunar and Martian robotic and human exploration objectives, cryogenic rocket engines offer the potential for higher performance and greater architecture/mission flexibility. In-situ cryogenic propellant production could enable a more robust exploration program by significantly reducing the propellant mass delivered to low earth orbit, thus warranting the evaluation of cryogenic rocket engines versus the hypergolic bi-propellant engines used in the Apollo program. A multi-use engine. one which can provide the functionality that separate engines provided in the Apollo mission architecture, is desirable for lunar and Mars exploration missions because it increases overall architecture effectiveness through commonality and modularity. The engine requirement derivation process must address each unique mission application and each unique phase within each mission. The resulting requirements, such as thrust level, performance, packaging, bum duration, number of operations; required impulses for each trajectory phase; operation after extended space or surface exposure; availability for inspection and maintenance; throttle range for planetary descent, ascent, acceleration limits and many more must be addressed. Within engine system studies, the system and component technology, capability, and risks must be evaluated and a balance between the appropriate amount of technology-push and technology-pull must be addressed. This paper will summarize many of the key technology challenges associated with using high-performance cryogenic liquid propellant rocket engine systems and components in the exploration program architectures. The paper is divided into two areas. The first area describes how the mission

  6. Technology Challenges for Deep-Throttle Cryogenic Engines for Space Exploration

    NASA Astrophysics Data System (ADS)

    Brown, Kendall K.; Nelson, Karl W.

    2005-02-01

    Historically, cryogenic rocket engines have not been used for in-space applications due to their additional complexity, the mission need for high reliability, and the challenges of propellant boil-off. While the mission and vehicle architectures are not yet defined for the lunar and Martian robotic and human exploration objectives, cryogenic rocket engines offer the potential for higher performance and greater architecture/mission flexibility. In-situ cryogenic propellant production could enable a more robust exploration program by significantly reducing the propellant mass delivered to low earth orbit, thus warranting the evaluation of cryogenic rocket engines versus the hypergolic bipropellant engines used in the Apollo program. A multi-use engine, one which can provide the functionality that separate engines provided in the Apollo mission architecture, is desirable for lunar and Mars exploration missions because it increases overall architecture effectiveness through commonality and modularity. The engine requirement derivation process must address each unique mission application and each unique phase within each mission. The resulting requirements, such as thrust level, performance, packaging, burn duration, number of operations; required impulses for each trajectory phase; operation after extended space or surface exposure; availability for inspection and maintenance; throttle range for planetary descent, ascent, acceleration limits and many more must be addressed. Within engine system studies, the system and component technology, capability, and risks must be evaluated and a balance between the appropriate amount of technology-push and technology-pull must be addressed. This paper will summarize many of the key technology challenges associated with using high-performance cryogenic liquid propellant rocket engine systems and components in the exploration program architectures. The paper is divided into two areas. The first area describes how the mission

  7. Semiquantum key distribution with secure delegated quantum computation

    PubMed Central

    Li, Qin; Chan, Wai Hong; Zhang, Shengyu

    2016-01-01

    Semiquantum key distribution allows a quantum party to share a random key with a “classical” party who only can prepare and measure qubits in the computational basis or reorder some qubits when he has access to a quantum channel. In this work, we present a protocol where a secret key can be established between a quantum user and an almost classical user who only needs the quantum ability to access quantum channels, by securely delegating quantum computation to a quantum server. We show the proposed protocol is robust even when the delegated quantum server is a powerful adversary, and is experimentally feasible with current technology. As one party of our protocol is the most quantum-resource efficient, it can be more practical and significantly widen the applicability scope of quantum key distribution. PMID:26813384

  8. Positioning a Paediatric Compounded Non-Sterile Product Electronic Repository (pCNPeRx) within the Health Information Technology Infrastructure

    PubMed Central

    Parrish, Richard H.

    2015-01-01

    Numerous gaps in the current medication use system impede complete transmission of electronically identifiable and standardized extemporaneous formulations as well as a uniform approach to medication therapy management (MTM) for paediatric patients. The Pharmacy Health Information Technology Collaborative (Pharmacy HIT) identified six components that may have direct importance for pharmacy related to medication use in children. This paper will discuss key positions within the information technology infrastructure (HIT) where an electronic repository for the medication management of paediatric patients’ compounded non-sterile products (pCNP) and care provision could be housed optimally to facilitate and maintain transmission of e-prescriptions (eRx) from initiation to fulfillment. Further, the paper will propose key placement requirements to provide for maximal interoperability of electronic medication management systems to minimize disruptions across the continuum of care. PMID:28970375

  9. Multiparty Quantum Secret Sharing of Key Using Practical Faint Laser Pulses

    NASA Astrophysics Data System (ADS)

    Zhang, Zhan-Jun; Man, Zhong-Xiao

    2005-07-01

    Based on a bidirectional quantum key distribution protocol [Phys. Rev. A 70 (2004) 012311], we propose a (m-1,m-1)-threshold scheme of m (m >= 3)-party quantum secret sharing of key by using practical faint laser pulses. In our scheme, if all the m-1 sharers collaborate, they can obtain the joint secret key from the message sender. Our scheme is more feasible according to the present-day technology.

  10. Long-distance practical quantum key distribution by entanglement swapping.

    PubMed

    Scherer, Artur; Sanders, Barry C; Tittel, Wolfgang

    2011-02-14

    We develop a model for practical, entanglement-based long-distance quantum key distribution employing entanglement swapping as a key building block. Relying only on existing off-the-shelf technology, we show how to optimize resources so as to maximize secret key distribution rates. The tools comprise lossy transmission links, such as telecom optical fibers or free space, parametric down-conversion sources of entangled photon pairs, and threshold detectors that are inefficient and have dark counts. Our analysis provides the optimal trade-off between detector efficiency and dark counts, which are usually competing, as well as the optimal source brightness that maximizes the secret key rate for specified distances (i.e. loss) between sender and receiver.

  11. Overview of diffraction gratings technologies for space-flight satellites and astronomy

    NASA Astrophysics Data System (ADS)

    Cotel, Arnaud; Liard, Audrey; Desserouer, Frédéric; Bonnemason, Francis; Pichon, Pierre

    2014-09-01

    The diffraction gratings are widely used in Space-flight satellites for spectrograph instruments or in ground-based telescopes in astronomy. The diffraction gratings are one of the key optical components of such systems and have to exhibit very high optical performances. HORIBA Jobin Yvon S.A.S. (part of HORIBA Group) is in the forefront of such gratings development for more than 40 years. During the past decades, HORIBA Jobin Yvon (HJY) has developed a unique expertise in diffraction grating design and manufacturing processes for holographic, ruled or etched gratings. We will present in this paper an overview of diffraction grating technologies especially designed for space and astronomy applications. We will firstly review the heritage of the company in this field with the space qualification of different grating types. Then, we will describe several key grating technologies developed for specific space or astronomy projects: ruled blazed low groove density plane reflection grating, holographic blazed replica plane grating, high-groove density holographic toroidal and spherical grating and transmission Fused Silica Etched (FSE) grismassembled grating.

  12. An expert system for diagnostics and estimation of steam turbine components condition

    NASA Astrophysics Data System (ADS)

    Murmansky, B. E.; Aronson, K. E.; Brodov, Yu. M.

    2017-11-01

    The report describes an expert system of probability type for diagnostics and state estimation of steam turbine technological subsystems components. The expert system is based on Bayes’ theorem and permits to troubleshoot the equipment components, using expert experience, when there is a lack of baseline information on the indicators of turbine operation. Within a unified approach the expert system solves the problems of diagnosing the flow steam path of the turbine, bearings, thermal expansion system, regulatory system, condensing unit, the systems of regenerative feed-water and hot water heating. The knowledge base of the expert system for turbine unit rotors and bearings contains a description of 34 defects and of 104 related diagnostic features that cause a change in its vibration state. The knowledge base for the condensing unit contains 12 hypotheses and 15 evidence (indications); the procedures are also designated for 20 state parameters estimation. Similar knowledge base containing the diagnostic features and faults hypotheses are formulated for other technological subsystems of turbine unit. With the necessary initial information available a number of problems can be solved within the expert system for various technological subsystems of steam turbine unit: for steam flow path it is the correlation and regression analysis of multifactor relationship between the vibration parameters variations and the regime parameters; for system of thermal expansions it is the evaluation of force acting on the longitudinal keys depending on the temperature state of the turbine cylinder; for condensing unit it is the evaluation of separate effect of the heat exchange surface contamination and of the presence of air in condenser steam space on condenser thermal efficiency performance, as well as the evaluation of term for condenser cleaning and for tube system replacement and so forth. With a lack of initial information the expert system enables to formulate a diagnosis

  13. Does This Really Work? The Keys to Implementing New Technology while Providing Evidence that Technology Is Successful

    ERIC Educational Resources Information Center

    Sawtelle, Sara

    2008-01-01

    Proving that technology works is not as simple as proving that a new vendor for art supplies is more cost effective. Technology effectiveness requires both the right software and the right implementation. Just having the software is not enough. Proper planning, training, leadership, support, pedagogy, and software use--along with many other…

  14. Arthropod surveillance programs: Basic components, strategies, and analysis

    USDA-ARS?s Scientific Manuscript database

    Effective entomological surveillance planning stresses a careful consideration of methodology, trapping technologies, and analysis techniques. Herein, the basic principles and technological components of arthropod surveillance plans are described, as promoted in the symposium “Advancements in arthro...

  15. Lifecycle Prognostics Architecture for Selected High-Cost Active Components

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    N. Lybeck; B. Pham; M. Tawfik

    There are an extensive body of knowledge and some commercial products available for calculating prognostics, remaining useful life, and damage index parameters. The application of these technologies within the nuclear power community is still in its infancy. Online monitoring and condition-based maintenance is seeing increasing acceptance and deployment, and these activities provide the technological bases for expanding to add predictive/prognostics capabilities. In looking to deploy prognostics there are three key aspects of systems that are presented and discussed: (1) component/system/structure selection, (2) prognostic algorithms, and (3) prognostics architectures. Criteria are presented for component selection: feasibility, failure probability, consequences of failure,more » and benefits of the prognostics and health management (PHM) system. The basis and methods commonly used for prognostics algorithms are reviewed and summarized. Criteria for evaluating PHM architectures are presented: open, modular architecture; platform independence; graphical user interface for system development and/or results viewing; web enabled tools; scalability; and standards compatibility. Thirteen software products were identified and discussed in the context of being potentially useful for deployment in a PHM program applied to systems in a nuclear power plant (NPP). These products were evaluated by using information available from company websites, product brochures, fact sheets, scholarly publications, and direct communication with vendors. The thirteen products were classified into four groups of software: (1) research tools, (2) PHM system development tools, (3) deployable architectures, and (4) peripheral tools. Eight software tools fell into the deployable architectures category. Of those eight, only two employ all six modules of a full PHM system. Five systems did not offer prognostic estimates, and one system employed the full health monitoring suite but lacked

  16. Teaching Technological Knowledge: Determining and Supporting Student Learning of Technological Concepts

    ERIC Educational Resources Information Center

    Compton, Vicki J.; Compton, Ange D.

    2013-01-01

    This paper reports on findings related to Technological Knowledge from Stage Two of the "Technological Knowledge and Nature of Technology: Implications for teaching and learning" ("TKNoT: Imps") research project undertaken in 2009. A key focus in Stage Two was the trialing of different teaching strategies to determine how…

  17. A Discussion of Oxygen Recovery Definitions and Key Performance Parameters for Closed-Loop Atmosphere Revitalization Life Support Technology Development

    NASA Technical Reports Server (NTRS)

    Abney, Morgan B.; Perry, Jay L.

    2016-01-01

    Over the last 55 years, NASA has evolved life support for crewed space exploration vehicles from simple resupply during Project Mercury to the complex and highly integrated system of systems aboard the International Space Station. As NASA targets exploration destinations farther from low Earth orbit and mission durations of 500 to 1000 days, life support systems must evolve to meet new requirements. In addition to having more robust, reliable, and maintainable hardware, limiting resupply becomes critical for managing mission logistics and cost. Supplying a crew with the basics of food, water, and oxygen become more challenging as the destination ventures further from Earth. Aboard ISS the Atmosphere Revitalization Subsystem (ARS) supplies the crew's oxygen demand by electrolyzing water. This approach makes water a primary logistics commodity that must be managed carefully. Chemical reduction of metabolic carbon dioxide (CO2) provides a method of recycling oxygen thereby reducing the net ARS water demand and therefore minimizing logistics needs. Multiple methods have been proposed to achieve this recovery and have been reported in the literature. However, depending on the architecture and the technology approach, "oxygen recovery" can be defined in various ways. This discontinuity makes it difficult to compare technologies directly. In an effort to clarify community discussions of Oxygen Recovery, we propose specific definitions and describe the methodology used to arrive at those definitions. Additionally, we discuss key performance parameters for Oxygen Recovery technology development including challenges with comparisons to state-of-the-art.

  18. Recent Advances in Power Conversion and Heat Rejection Technology for Fission Surface Power

    NASA Technical Reports Server (NTRS)

    Mason, Lee

    2010-01-01

    Under the Exploration Technology Development Program, the National Aeronautics and Space Administration (NASA) and the Department of Energy (DOE) are jointly developing Fission Surface Power (FSP) technology for possible use in human missions to the Moon and Mars. A preliminary reference concept was generated to guide FSP technology development. The concept consists of a liquid-metal-cooled reactor, Stirling power conversion, and water heat rejection, with Brayton power conversion as a backup option. The FSP project has begun risk reduction activities on some key components with the eventual goal of conducting an end-to-end, non-nuclear, integrated system test. Several power conversion and heat rejection hardware prototypes have been built and tested. These include multi-kilowatt Stirling and Brayton power conversion units, titanium-water heat pipes, and composite radiator panels.

  19. Dual use of photonic components in radiation environments

    NASA Astrophysics Data System (ADS)

    Taylor, Edward W.

    1994-06-01

    The steady evolution of and increased requirement for using photonic technologies within the commercial market coupled with decreased defense spending has brought forth new national philosophies regarding widespread use of the technology in both military and commercial sectors. Many commercially available photonic components (i.e., optical fibers, laser diodes, semiconductor detectors, detector arrays, spatial light modulators, integrated optic circuitry and other similar optoelectronic and electro-optic devices are being scrutinized for utility, cost effectiveness and dual-use in a variety of applications. One important area of application is space. This paper will discuss the current state-of-the-art and utility of qualifying and using several mature photonic component technologies in commercial and defense application areas.

  20. Successful Implementation of Clinical Information Technology: Seven Key Lessons from CPOE.

    PubMed

    Gellert, G A; Hill, V; Bruner, K; Maciaz, G; Saucedo, L; Catzoela, L; Ramirez, R; Jacobs, W J; Nguyen, P; Patel, L; Webster, S L

    2015-01-01

    To identify and describe the most critical strategic and operational contributors to the successful implementation of clinical information technologies, as deployed within a moderate sized system of U.S. community hospitals. CHRISTUS Health is a multi-state system comprised of more than 350 services and 60 hospitals with over 9 000 physicians. The Santa Rosa region of CHRISTUS Health, located in greater San Antonio, Texas is comprised of three adult community hospital facilities and one Children's hospital each with bed capacities of 142-180. Computerized Patient Order Entry (CPOE) was first implemented in 2012 within a complex market environment. The Santa Rosa region has 2 417 credentialed physicians and 263 mid-level allied health professionals. This report focuses on the seven most valuable strategies deployed by the Health Informatics team in a large four hospital CHRISTUS region to achieve strong CPOE adoption and critical success lessons learned. The findings are placed within the context of the literature describing best practices in health information technology implementation. While the elements described involved discrete de novo process generation to support implementation and operations, collectively they represent the creation of a new customer-centric service culture in our Health Informatics team, which has served as a foundation for ensuring strong clinical information technology adoption beyond CPOE. The seven success factors described are not limited in their value to and impact on CPOE adoption, but generalize to - and can advance success in - varied other clinical information technology implementations across diverse hospitals. A number of these factors are supported by reports in the literature of other institutions' successful implementations of CPOE and other clinical information technologies, and while not prescriptive to other settings, may be adapted to yield value elsewhere.

  1. Laser Micromachining Fabrication of THz Components

    NASA Technical Reports Server (NTRS)

    DrouetdAubigny, C.; Walker, C.; Jones, B.; Groppi, C.; Papapolymerou, J.; Tavenier, C.

    2001-01-01

    Laser micromachining techniques can be used to fabricate high-quality waveguide structures and quasi-optical components to micrometer accuracies. Successful GHz designs can be directly scaled to THz frequencies. We expect this promising technology to allow the construction of the first fully integrated THz heterodyne imaging arrays. At the University of Arizona, construction of the first laser micromachining system designed for THz waveguide components fabrication has been completed. Once tested and characterized our system will be used to construct prototype THz lx4 focal plane mixer arrays, magic tees, AR coated silicon lenses, local oscillator source phase gratings, filters and more. Our system can micro-machine structures down to a few microns accuracy and up to 6 inches across in a short time. This paper discusses the design and performance of our micromachining system, and illustrates the type, range and performance of components this exciting new technology will make accessible to the THz community.

  2. Measures of International Manufacturing and Trade of Clean Energy Technologies

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Engel-Cox, Jill; Sandor, Debbie; Keyser, David

    The technologies that produce clean energy, such as solar photovoltaic panels and lithium ion batteries for electric vehicles, are globally manufactured and traded. As demand and deployment of these technologies grows exponentially, the innovation to reach significant economies of scale and drive down energy production costs becomes less in the technology and more in the manufacturing of the technology. Manufacturing innovations and other manufacturing decisions can reduce costs of labor, materials, equipment, operating costs, and transportation, across all the links in the supply chain. To better understand the manufacturing aspect of the clean energy economy, we have developed key metricsmore » for systematically measuring and benchmarking international manufacturing of clean energy technologies. The metrics are: trade, market size, manufacturing value-added, and manufacturing capacity and production. These metrics were applied to twelve global economies and four representative technologies: wind turbine components, crystalline silicon solar photovoltaic modules, vehicle lithium ion battery cells, and light emitting diode packages for efficient lighting and other consumer products. The results indicated that clean energy technologies are being developed via complex, dynamic, and global supply chains, with individual economies benefiting from different technologies and links in the supply chain, through both domestic manufacturing and global trade.« less

  3. Point-of-care technology: integration for improved delivery of care.

    PubMed

    Gregory, Debbie; Buckner, Martha

    2014-01-01

    The growing complexity of technology, equipment, and devices involved in patient care delivery can be staggering and overwhelming. Technology is intended to be a tool to help clinicians, but it can also be a frustrating hindrance if not thoughtfully planned and strategically aligned. Critical care nurses are key partners in the collaborations needed to improve safety and quality through health information technology (IT). Nurses must advocate for systems that are interoperable and adapted to the context of care experiences. The involvement and collaboration between clinicians, information technology specialists, biomedical engineers, and vendors has never been more relevant and applicable. Working together strategically with a shared vision can effectively provide a seamless clinical workflow, maximize technology investments, and ultimately improve patient care delivery and outcomes. Developing a strategic integrated clinical and IT roadmap is a critical component of today's health care environment. How can technology strategy be aligned from the executive suite to the bedside caregiver? What is the model for using clinical workflows to drive technology adoption? How can the voice of the critical care nurse strengthen this process? How can success be assured from the initial assessment and selection of technology to a sustainable support model? What is the vendor's role as a strategic partner and "co-caregiver"?

  4. The key to success: Gelled-electrolyte and optimized separators for stationary lead-acid batteries

    NASA Astrophysics Data System (ADS)

    Toniazzo, Valérie

    The lead acid technology is nowadays considered one of the best suited for stationary applications. Both gel and AGM batteries are complementary technologies and can provide reliability and efficiency due to the constant optimization of the battery design and components. However, gelled-electrolyte batteries remain the preferred technology due to a better manufacturing background and show better performance mainly at low and moderate discharge rates. Especially, using the gel technology allows to get rid of the numerous problems encountered in most AGM batteries: drainage, stratification, short circuits due to dendrites, and mostly premature capacity loss due to the release of internal cell compression. These limitations are the result of the evident lack of an optimal separation system. In gel batteries, on the contrary, highly efficient polymeric separators are nowadays available. Especially, microporous separators based on PVC and silica have shown the best efficiency for nearly 30 years all over the world, and especially in Europe, where the gel technology was born. The improved performance of these separators is explained by the unique extrusion process, which leads to excellent wettability, and optimized physical properties. Because they are the key for the battery success, continuous research and development on separators have led to improved properties, which render the separator even better adapted to the more recent gel technology: the pore size distribution has been optimized to allow good oxygen transfer while avoiding dendrite growth, the pore volume has been increased, the electrical resistance and acid displacement reduced to such an extent that the electrical output of batteries has been raised both in terms of higher capacity and longer cycle life.

  5. Life assessment of structural components using inelastic finite element analyses

    NASA Technical Reports Server (NTRS)

    Arya, Vinod K.; Halford, Gary R.

    1993-01-01

    The need for enhanced and improved performance of structural components subject to severe cyclic thermal/mechanical loadings, such as in the aerospace industry, requires development of appropriate solution technologies involving time-dependent inelastic analyses. Such analyses are mandatory to predict local stress-strain response and to assess more accurately the cyclic life time of structural components. The NASA-Lewis Research Center is cognizant of this need. As a result of concerted efforts at Lewis during the last few years, several such finite element solution technologies (in conjunction with the finite element program MARC) were developed and successfully applied to numerous uniaxial and multiaxial problems. These solution technologies, although developed for use with MARC program, are general in nature and can easily be extended for adaptation with other finite element programs such as ABAQUS, ANSYS, etc. The description and results obtained from two such inelastic finite element solution technologies are presented. The first employs a classical (non-unified) creep-plasticity model. An application of this technology is presented for a hypersonic inlet cowl-lip problem. The second of these technologies uses a unified creep-plasticity model put forth by Freed. The structural component for which this finite element solution technology is illustrated, is a cylindrical rocket engine thrust chamber. The advantages of employing a viscoplastic model for nonlinear time-dependent structural analyses are demonstrated. The life analyses for cowl-lip and cylindrical thrust chambers are presented. These analyses are conducted by using the stress-strain response of these components obtained from the corresponding finite element analyses.

  6. Development of Key Performance Indicators for the Engineering Technology Education Programs in Taiwan

    ERIC Educational Resources Information Center

    Lee, Lung-Sheng; Lai, Chun-Chin

    2004-01-01

    In comparison with engineering, engineering technology is more practical and purposeful. The engineering technology education programs in Taiwan have been mainly offered in 56 universities/colleges of technology (UTs/CTs) and are anticipated to continuously improve their performance to prepare quality engineering technologists. However, it is…

  7. Information management and information technologies: keys to professional and business success.

    PubMed

    Otten, K W

    1984-01-01

    Personal computers, spreadsheets, decision support software, electronic mail and video disks are just a few of the innovations of information technology which attract the attention of information professionals and managers alike: they are all concerned with the rapidly changing face of information technology and how to cope with a changing competitive environment, personally, and for the benefit of their companies. This paper is the first in a monthly series which tries to illuminate some of the factors and changes which shape our future as professionals and managers. In so doing, it guides and motivates the reader to become "information literate," a prerequisite for personal advancement in an information-based economy. This first paper outlines the relationship between technological innovations, use of information tools and information management and what to consider in order to benefit from the information revolution. It explains the risks of becoming professionally obsolete and alerts the reader to get personally involved to remain or become "information and computer literate."

  8. An Exploratory Qualitative Inquiry of Key Indicators on IT Disaster Recovery Planning

    ERIC Educational Resources Information Center

    Gardner, Brian

    2016-01-01

    Disaster recovery planning is a crucial component to maintaining a business's economic stability. However, it is unclear how key performance indicators (KPIs) are perceived in the emergency medical service (EMS) industry during the disaster recover planning process. The problem addressed in this study was to understand KPIs and their components.…

  9. Development of Cryogenic Engine for GSLV MkIII: Technological Challenges

    NASA Astrophysics Data System (ADS)

    Praveen, RS; Jayan, N.; Bijukumar, KS; Jayaprakash, J.; Narayanan, V.; Ayyappan, G.

    2017-02-01

    Cryogenic engine capable of delivering 200 kN thrust is being developed for the first time in the country by ISRO for powering the upper stage of GSLV Mk-III, the next generation launch vehicle of ISRO capable of launching four tonne class satellites to Geo-synchronous Transfer Orbit(GTO). Development of this engine started a decade ago when various sub-systems development and testing were taken up. Starting with injector element development, the design, realization and testing of the major sub-systems viz the gas generator, turbopumps, start-up system and thrust chamber have been successfully done in a phased manner before conducting a series of developmental tests in the integrated engine mode. Apart from the major sub-systems, many critical components like the igniter, control components etc were independently developed and qualified. During the development program many challenges were faced in almost all areas of propulsion engineering. Systems engineering of the engine was another key challenge in the realization. This paper gives an outlook on various technological challenges faced in the key areas related to the engine development, insight to the solutions and measures taken to overcome the challenges.

  10. [New method for analyzing pharmacodynamic material basis of traditional Chinese medicines by using specific knockout technology with monoclonal antibodies].

    PubMed

    Zhao, Yan; Qu, Hui-Hua; Wang, Qing-Guo

    2013-09-01

    Study on pharmacodynamic material basis of traditional Chinese medicines is one of the key issues for the modernization of traditional Chinese medicine. Having introduced the monoclonal antibody technology into the study on pharmacodynamic material basis of traditional Chinese medicines, the author prepared the immunoaffinity chromatography column by using monoclonal antibodies in active components of traditional Chinese medicines, so as to selectively knock out the component from herbs or traditional Chinese medicine compounds, while preserving all of the other components and keeping their amount and ratio unchanged. A comparative study on pharmacokinetics and pharmacodynamics was made to explicitly reveal the correlation between the component and the main purpose of traditional Chinese medicines and compounds. The analysis on pharmacodynamic material basis of traditional Chinese medicines by using specific knockout technology with monoclonal antibodies is a new method for study pharmacodynamic material basis in line with the characteristics of traditional Chinese medicines. Its results can not only help study material basis from a new perspective, but also help find the modern scientific significance in single herb or among compounds of traditional Chinese medicines.

  11. Microwave components for cellular portable radiotelephone

    NASA Astrophysics Data System (ADS)

    Muraguchi, Masahiro; Aikawa, Masayoshi

    1995-09-01

    Mobile and personal communication systems are expected to represent a huge market for microwave components in the coming years. A number of components in silicon bipolar, silicon Bi-CMOS, GaAs MESFET, HBT and HEMT are now becoming available for system application. There are tradeoffs among the competing technologies with regard to performance, cost, reliability and time-to-market. This paper describes process selection and requirements of cost and r.f. performances to microwave semiconductor components for digital cellular and cordless telephones. Furthermore, new circuit techniques which were developed by NTT are presented.

  12. The Next Technology Revolution - Nano Electronic Technology

    NASA Astrophysics Data System (ADS)

    Turlik, Iwona

    2004-03-01

    Nanotechnology is a revolutionary engine that will engender enormous changes in a vast majority of today's industries and markets, while potentially creating whole new industries. The impact of nanotechnology is particularly significant in the electronics industry, which is constantly driven by the need for higher performance, increased functionality, smaller size and lower cost. Nanotechnology can influence many of the hundreds of components that are typically assembled to manufacture modern electronic devices. Motorola manufactures electronics for a wide range of industries and communication products. In this presentation, the typical components of a cellular phone are outlined and technology requirements for future products, the customer benefits, and the potential impact of nanotechnology on many of the components are discussed. Technology needs include reliable materials supply, processes for high volume production, experimental and simulation tools, etc. For example, even routine procedures such as failure characterization may require the development of new tools for investigating nano-scale phenomena. Business needs include the development of an effective, high volume supply chain for nano-materials and devices, disruptive product platforms, and visible performance impact on the end consumer. An equally significant long-term industry need is the availability of science and engineering graduates with a multidisciplinary focus and a deep understanding of the fundamentals of nano-technology, that can harness the technology to create revolutionary products.

  13. Reducing Weight for Transportation Applications: Technology Challenges and Opportunities

    NASA Astrophysics Data System (ADS)

    Taub, Alan I.

    Today's land, sea and air transportation industries — as a business necessity — are focused on technology solutions that will make vehicles more sustainable in terms of energy, the environment, safety and affordability. Reducing vehicle weight is a key enabler for meeting these challenges as well as increasing payload and improving performance. The potential weight reductions from substituting lightweight metals (advanced high-strength steels, aluminum, magnesium and titanium alloys) are well established. For magnesium castings, weight savings of 60% have been reported [1]. The value of weight reduction depends on the transportation sector and ranges from about 5/kg saved for automobiles to over 500/kg saved for aircraft [2]. The challenge is to optimize the material properties and develop robust, high volume, manufacturing technologies and the associated supply chain to fabricate components and subsystems at the appropriate cost for each application.

  14. Technology development program for an advanced microsheet glass concentrator

    NASA Technical Reports Server (NTRS)

    Richter, Scott W.; Lacy, Dovie E.

    1990-01-01

    Solar Dynamic Space Power Systems are candidate electrical power generating systems for future NASA missions. One of the key components in a solar dynamic power system is the concentrator which collects the sun's energy and focuses it into a receiver. In 1985, the NASA Lewis Research Center initiated the Advanced Solar Dynamic Concentrator Program with funding from NASA's Office of Aeronautics and Space Technology (OAST). The objectives of the Advanced Concentrator Program is to develop the technology that will lead to lightweight, highly reflective, accurate, scaleable, and long lived (7 to 10 years) space solar dynamic concentrators. The Advanced Concentrator Program encompasses new and innovative concepts, fabrication techniques, materials selection, and simulated space environmental testing. The Advanced Microsheet Glass Concentrator Program, a reflector concept, that is currently being investigated both in-house and under contract is discussed.

  15. Modeling and simulation: A key to future defense technology

    NASA Technical Reports Server (NTRS)

    Muccio, Anthony B.

    1993-01-01

    The purpose of this paper is to express the rationale for continued technological and scientific development of the modeling and simulation process for the defense industry. The defense industry, along with a variety of other industries, is currently being forced into making sacrifices in response to the current economic hardships. These sacrifices, which may not compromise the safety of our nation, nor jeopardize our current standing as the world peace officer, must be concentrated in areas which will withstand the needs of the changing world. Therefore, the need for cost effective alternatives of defense issues must be examined. This paper provides support that the modeling and simulation process is an economically feasible process which will ensure our nation's safety as well as provide and keep up with the future technological developments and demands required by the defense industry. The outline of this paper is as follows: introduction, which defines and describes the modeling and simulation process; discussion, which details the purpose and benefits of modeling and simulation and provides specific examples of how the process has been successful; and conclusion, which summarizes the specifics of modeling and simulation of defense issues and lends the support for its continued use in the defense arena.

  16. Scaling-Up Solid Oxide Membrane Electrolysis Technology for Magnesium Production

    NASA Astrophysics Data System (ADS)

    Pati, Soobhankar; Powell, Adam; Tucker, Steve; Derezinski, Steve

    Metal Oxygen Separation Technologies, Inc. (MOxST) is actively developing Solid Oxide Membrane (SOM) electrolysis technology for production of magnesium directly from its oxide. The vital component of this technology is the oxygen ion-conducting solid zirconia electrolyte separating the molten flux (a mixture of salts and oxide) and the inert anode. The zirconia not only protects the anode from the flux but also prevents anode gas back-reaction, increasing the efficiency. This makes it possible to produce low-cost high-purity magnesium and high-purity oxygen as a byproduct with no direct greenhouse gas emissions. In this paper we discuss the design modifications made to address the scaling-up challenges, particularly for producing magnesium in liquid form. The key accomplishment to date is the successful development of a prototype capable of producing few kilograms of magnesium per day. We will also describe the prerequisite properties of an inert anode and suitable materials for the same.

  17. An overview of the small engine component technology (SECT) studies. [commuter, rotorcraft, cruise missile and auxiliary power applications in year 2000

    NASA Technical Reports Server (NTRS)

    Vanco, M. R.; Wintucky, W. T.; Niedwiecki, R. W.

    1986-01-01

    The objectives of the joint NASA/Army SECT studies were to identify high payoff technologies for year 2000 small gas turbine engine applications and to provide a technology plan for guiding future research and technology efforts applicable to rotorcraft, commuter and general aviation aircraft and cruise missiles. Competitive contracts were awarded to Allison, AVCO Lycoming, Garrett, Teledyne CAE and Williams International. This paper presents an overview of the contractors' study efforts for the commuter, rotorcraft, cruise missile, and auxiliary power (APU) applications with engines in the 250 to 1,000 horsepower size range. Reference aircraft, missions and engines were selected. Advanced engine configurations and cycles with projected year 2000 component technologies were evaluated and compared with a reference engine selected by the contractor. For typical commuter and rotorcraft applications, fuel savings of 22 percent to 42 percent can be attained. For $1/gallon and $2/gallon fuel, reductions in direct operating cost range from 6 percent to 16 percent and from 11 percent to 17 percent respectively. For subsonic strategic cruise missile applications, fuel savings of 38 percent to 54 percent can be achieved which allows 35 percent to 60 percent increase in mission range and life cycle cost reductions of 40 percent to 56 percent. High payoff technologies have been identified for all applications.

  18. Audiovisual Programming. Technology Learning Activity. Teacher Edition. Technology Education Series.

    ERIC Educational Resources Information Center

    Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

    This packet of technology learning activity (TLA) materials on audiovisual programming for students in grades 6-10 consists of a technology education overview, information on use, and the instructor's and student's sections. The overview discusses the technology education program and materials. Components of the instructor's and student's sections…

  19. Health Occupations. Technology Learning Activity. Teacher Edition. Technology Education Series.

    ERIC Educational Resources Information Center

    Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

    This packet of technology learning activity (TLA) materials on health occupations for students in grades 6-10 consists of a technology education overview, information on use, and instructor's and student's sections. The overview discusses the technology education program and materials. Components of the instructor's and student's sections are…

  20. Electronic Publishing. Technology Learning Activity. Teacher Edition. Technology Education Series.

    ERIC Educational Resources Information Center

    Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

    This packet of technology learning activity (TLA) materials on electronic publishing for students in grades 6-10 consists of a technology education overview, information on use, and the instructor's and student's sections. The overview discusses the technology education program and materials. Components of the instructor and student sections are…

  1. Career Search. Technology Learning Activity. Teacher Edition. Technology Education Series.

    ERIC Educational Resources Information Center

    Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

    This packet of technology learning activity (TLA) materials on career search for students in grades 6-10 consists of a technology education overview, information on use, and the instructor's and student's sections. The overview discusses the technology education program and materials. Components of the instructor's and student's sections are…

  2. Textile-Based Electronic Components for Energy Applications: Principles, Problems, and Perspective

    PubMed Central

    Kaushik, Vishakha; Lee, Jaehong; Hong, Juree; Lee, Seulah; Lee, Sanggeun; Seo, Jungmok; Mahata, Chandreswar; Lee, Taeyoon

    2015-01-01

    Textile-based electronic components have gained interest in the fields of science and technology. Recent developments in nanotechnology have enabled the integration of electronic components into textiles while retaining desirable characteristics such as flexibility, strength, and conductivity. Various materials were investigated in detail to obtain current conductive textile technology, and the integration of electronic components into these textiles shows great promise for common everyday applications. The harvest and storage of energy in textile electronics is a challenge that requires further attention in order to enable complete adoption of this technology in practical implementations. This review focuses on the various conductive textiles, their methods of preparation, and textile-based electronic components. We also focus on fabrication and the function of textile-based energy harvesting and storage devices, discuss their fundamental limitations, and suggest new areas of study. PMID:28347078

  3. Textile-Based Electronic Components for Energy Applications: Principles, Problems, and Perspective.

    PubMed

    Kaushik, Vishakha; Lee, Jaehong; Hong, Juree; Lee, Seulah; Lee, Sanggeun; Seo, Jungmok; Mahata, Chandreswar; Lee, Taeyoon

    2015-09-07

    Textile-based electronic components have gained interest in the fields of science and technology. Recent developments in nanotechnology have enabled the integration of electronic components into textiles while retaining desirable characteristics such as flexibility, strength, and conductivity. Various materials were investigated in detail to obtain current conductive textile technology, and the integration of electronic components into these textiles shows great promise for common everyday applications. The harvest and storage of energy in textile electronics is a challenge that requires further attention in order to enable complete adoption of this technology in practical implementations. This review focuses on the various conductive textiles, their methods of preparation, and textile-based electronic components. We also focus on fabrication and the function of textile-based energy harvesting and storage devices, discuss their fundamental limitations, and suggest new areas of study.

  4. Antenna technology for advanced mobile communication systems

    NASA Technical Reports Server (NTRS)

    Rammos, Emmanuel; Roederer, Antoine; Rogard, Roger

    1988-01-01

    The onboard antenna front end is the key subsystem conditioning configuration and performance of mobile communication satellites. The objectives of this paper are to demonstrate this key role and to review L-band satellite antenna technology for earth coverage and regional applications. Multibeam arrays are first discussed, then unfurlable and inflatable reflector antennas are described. These technologies are now qualified in Europe for future mobile systems, for which the optimum choice of antenna technology has been found to be the key to efficient use of spectrum and power resources.

  5. Single molecule force measurements of perlecan/HSPG2: A key component of the osteocyte pericellular matrix.

    PubMed

    Wijeratne, Sithara S; Martinez, Jerahme R; Grindel, Brian J; Frey, Eric W; Li, Jingqiang; Wang, Liyun; Farach-Carson, Mary C; Kiang, Ching-Hwa

    2016-03-01

    Perlecan/HSPG2, a large, monomeric heparan sulfate proteoglycan (HSPG), is a key component of the lacunar canalicular system (LCS) of cortical bone, where it is part of the mechanosensing pericellular matrix (PCM) surrounding the osteocytic processes and serves as a tethering element that connects the osteocyte cell body to the bone matrix. Within the pericellular space surrounding the osteocyte cell body, perlecan can experience physiological fluid flow drag force and in that capacity function as a sensor to relay external stimuli to the osteocyte cell membrane. We previously showed that a reduction in perlecan secretion alters the PCM fiber composition and interferes with bone's response to a mechanical loading in vivo. To test our hypothesis that perlecan core protein can sustain tensile forces without unfolding under physiological loading conditions, atomic force microscopy (AFM) was used to capture images of perlecan monomers at nanoscale resolution and to perform single molecule force measurement (SMFMs). We found that the core protein of purified full-length human perlecan is of suitable size to span the pericellular space of the LCS, with a measured end-to-end length of 170±20 nm and a diameter of 2-4 nm. Force pulling revealed a strong protein core that can withstand over 100 pN of tension well over the drag forces that are estimated to be exerted on the individual osteocyte tethers. Data fitting with an extensible worm-like chain model showed that the perlecan protein core has a mean elastic constant of 890 pN and a corresponding Young's modulus of 71 MPa. We conclude that perlecan has physical properties that would allow it to act as a strong but elastic tether in the LCS. Copyright © 2015 International Society of Matrix Biology. Published by Elsevier B.V. All rights reserved.

  6. Constructing a Cross-Domain Resource Inventory: Key Components and Results of the EarthCube CINERGI Project.

    NASA Astrophysics Data System (ADS)

    Zaslavsky, I.; Richard, S. M.; Malik, T.; Hsu, L.; Gupta, A.; Grethe, J. S.; Valentine, D. W., Jr.; Lehnert, K. A.; Bermudez, L. E.; Ozyurt, I. B.; Whitenack, T.; Schachne, A.; Giliarini, A.

    2015-12-01

    While many geoscience-related repositories and data discovery portals exist, finding information about available resources remains a pervasive problem, especially when searching across multiple domains and catalogs. Inconsistent and incomplete metadata descriptions, disparate access protocols and semantic differences across domains, and troves of unstructured or poorly structured information which is hard to discover and use are major hindrances toward discovery, while metadata compilation and curation remain manual and time-consuming. We report on methodology, main results and lessons learned from an ongoing effort to develop a geoscience-wide catalog of information resources, with consistent metadata descriptions, traceable provenance, and automated metadata enhancement. Developing such a catalog is the central goal of CINERGI (Community Inventory of EarthCube Resources for Geoscience Interoperability), an EarthCube building block project (earthcube.org/group/cinergi). The key novel technical contributions of the projects include: a) development of a metadata enhancement pipeline and a set of document enhancers to automatically improve various aspects of metadata descriptions, including keyword assignment and definition of spatial extents; b) Community Resource Viewers: online applications for crowdsourcing community resource registry development, curation and search, and channeling metadata to the unified CINERGI inventory, c) metadata provenance, validation and annotation services, d) user interfaces for advanced resource discovery; and e) geoscience-wide ontology and machine learning to support automated semantic tagging and faceted search across domains. We demonstrate these CINERGI components in three types of user scenarios: (1) improving existing metadata descriptions maintained by government and academic data facilities, (2) supporting work of several EarthCube Research Coordination Network projects in assembling information resources for their domains

  7. Entropy Driven Self-Assembly in Charged Lock-Key Particles.

    PubMed

    Odriozola, Gerardo; Lozada-Cassou, Marcelo

    2016-07-07

    In this work we study the lock-key model successfully used in supramolecular chemistry and particles self-assembly and gain further insight into the infinite diluted limit of the lock and key, depletant mediated, effective attraction. We discuss the depletant forces and entropy approaches to self-assembly and give details on the different contributions to the net force for a charged lock and key pair immersed in a solvent plus a primitive model electrolyte. We show a strong correlation of the force components behavior and the underlying processes of co-ion and solvent release from the cavity. In addition, we put into context the universal behavior observed for the energy-distance curves when changing the lock and key to solvent size ratio. Basically, we now show that this behavior is not always achieved and depends on the particular system geometry. Finally, we present a qualitative good agreement with experiments when changing the electrolyte concentration, valence, and cavity-key size ratio.

  8. Positioning Technology and Engineering Education as a Key Force in STEM Education

    ERIC Educational Resources Information Center

    Strimel, Greg; Grubbs, Michael E.

    2016-01-01

    As the presence of engineering content and practices increases in science education, the distinction between the two fields of science and technology education becomes even more vague than previously theorized. Furthermore, the addition of engineering to the title of the profession raises the question of the true aim of technology education. As a…

  9. Mission operations technology

    NASA Astrophysics Data System (ADS)

    Varsi, Giulio

    In the last decade, the operation of a spacecraft after launch has emerged as a major component of the total cost of the mission. This trend is sustained by the increasing complexity, flexibility, and data gathering capability of the space assets and by their greater reliability and consequent longevity. The trend can, however, be moderated by the progressive transfer of selected functions from the ground to the spacecraft and by application, on the ground, of new technology. Advances in ground operations derive from the introduction in the mission operations environment of advanced microprocessor-based workstations in the class of a few million instructions per second and from the selective application of artificial intelligence technology. In the last few years a number of these applications have been developed, tested in operational settings and successfully demonstrated to users. Some are now being integrated in mission operations facilities. An analysis of mission operations indicates that the key areas are: concurrent control of multiple missions; automated/interactive production of command sequences of high integrity at low cost; automated monitoring of spacecraft health and automated aides for fault diagnosis; automated allocation of resources; automated processing of science data; and high-fidelity, high-speed spacecraft simulation. Examples of major advances in selected areas are described.

  10. Design, Manufacture, and Experimental Serviceability Validation of ITER Blanket Components

    NASA Astrophysics Data System (ADS)

    Leshukov, A. Yu.; Strebkov, Yu. S.; Sviridenko, M. N.; Safronov, V. M.; Putrik, A. B.

    2017-12-01

    In 2014, the Russian Federation and the ITER International Organization signed two Procurement Arrangements (PAs) for ITER blanket components: 1.6.P1ARF.01 "Blanket First Wall" of February 14, 2014, and 1.6.P3.RF.01 "Blanket Module Connections" of December 19, 2014. The first PA stipulates development, manufacture, testing, and delivery to the ITER site of 179 Enhanced Heat Flux (EHF) First Wall (FW) Panels intended for withstanding the heat flux from the plasma up to 4.7MW/m2. Two Russian institutions, NIIEFA (Efremov Institute) and NIKIET, are responsible for the implementation of this PA. NIIEFA manufactures plasma-facing components (PFCs) of the EHF FW panels and performs the final assembly and testing of the panels, and NIKIET manufactures FW beam structures, load-bearing structures of PFCs, and all elements of the panel attachment system. As for the second PA, NIKIET is the sole official supplier of flexible blanket supports, electrical insulation key pads (EIKPs), and blanket module/vacuum vessel electrical connectors. Joint activities of NIKIET and NIIEFA for implementing PA 1.6.P1ARF.01 are briefly described, and information on implementation of PA 1.6.P3.RF.01 is given. Results of the engineering design and research efforts in the scope of the above PAs in 2015-2016 are reported, and results of developing the technology for manufacturing ITER blanket components are presented.

  11. Empirical Analysis of Optical Attenuator Performance in Quantum Key Distribution Systems Using a Particle Model

    DTIC Science & Technology

    2012-03-01

    EMPIRICAL ANALYSIS OF OPTICAL ATTENUATOR PERFORMANCE IN QUANTUM KEY DISTRIBUTION SYSTEMS USING A...DISTRIBUTION IS UNLIMITED AFIT/GCS/ENG/12-01 EMPIRICAL ANALYSIS OF OPTICAL ATTENUATOR PERFORMANCE IN QUANTUM KEY DISTRIBUTION SYSTEMS USING ...challenging as the complexity of actual implementation specifics are considered. Two components common to most quantum key distribution

  12. High-efficiency reconciliation for continuous variable quantum key distribution

    NASA Astrophysics Data System (ADS)

    Bai, Zengliang; Yang, Shenshen; Li, Yongmin

    2017-04-01

    Quantum key distribution (QKD) is the most mature application of quantum information technology. Information reconciliation is a crucial step in QKD and significantly affects the final secret key rates shared between two legitimate parties. We analyze and compare various construction methods of low-density parity-check (LDPC) codes and design high-performance irregular LDPC codes with a block length of 106. Starting from these good codes and exploiting the slice reconciliation technique based on multilevel coding and multistage decoding, we realize high-efficiency Gaussian key reconciliation with efficiency higher than 95% for signal-to-noise ratios above 1. Our demonstrated method can be readily applied in continuous variable QKD.

  13. Quantum-key-distribution protocol with pseudorandom bases

    NASA Astrophysics Data System (ADS)

    Trushechkin, A. S.; Tregubov, P. A.; Kiktenko, E. O.; Kurochkin, Y. V.; Fedorov, A. K.

    2018-01-01

    Quantum key distribution (QKD) offers a way for establishing information-theoretical secure communications. An important part of QKD technology is a high-quality random number generator for the quantum-state preparation and for post-processing procedures. In this work, we consider a class of prepare-and-measure QKD protocols, utilizing additional pseudorandomness in the preparation of quantum states. We study one of such protocols and analyze its security against the intercept-resend attack. We demonstrate that, for single-photon sources, the considered protocol gives better secret key rates than the BB84 and the asymmetric BB84 protocols. However, the protocol strongly requires single-photon sources.

  14. Revisioning Information and Communication Technology for Development (ICT4D) at the Comparative & International Education Society (CIES): A Five-Year Account (2009-2013)

    ERIC Educational Resources Information Center

    Kang, Haijun

    2014-01-01

    The purpose of this paper is to provide an account of how Information and Communication Technology (ICT) has evolved as a key topic and research area at the Comparative and International Education Society (CIES) conference. The past five years' CIES conference papers with an ICT component are reviewed for common development trends, opportunities,…

  15. GaAs MOEMS Technology

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    SPAHN, OLGA B.; GROSSETETE, GRANT D.; CICH, MICHAEL J.

    2003-03-01

    Many MEMS-based components require optical monitoring techniques using optoelectronic devices for converting mechanical position information into useful electronic signals. While the constituent piece-parts of such hybrid opto-MEMS components can be separately optimized, the resulting component performance, size, ruggedness and cost are substantially compromised due to assembly and packaging limitations. GaAs MOEMS offers the possibility of monolithically integrating high-performance optoelectronics with simple mechanical structures built in very low-stress epitaxial layers with a resulting component performance determined only by GaAs microfabrication technology limitations. GaAs MOEMS implicitly integrates the capability for radiation-hardened optical communications into the MEMS sensor or actuator component, a vitalmore » step towards rugged integrated autonomous microsystems that sense, act, and communicate. This project establishes a new foundational technology that monolithically combines GaAs optoelectronics with simple mechanics. Critical process issues addressed include selectivity, electrochemical characteristics, and anisotropy of the release chemistry, and post-release drying and coating processes. Several types of devices incorporating this novel technology are demonstrated.« less

  16. Overview of NASA GRC Stirling Technology Development

    NASA Technical Reports Server (NTRS)

    Schreiber, Jeffrey G.; Thieme, Lanny G.

    2004-01-01

    The Stirling Radioisotope Generator (SRG) is currently being developed by Lockheed Martin Astronautics (LMA) under contract to the Department of Energy (DOE). The generator will be a high efficiency electric power source for NASA Space Science missions with the ability to operate in vacuum or in an atmosphere such as on Mars. High efficiency is obtained through the use of free-piston Stirling power conversion. Power output will be greater than 100 watts at the beginning of life with the decline in power largely due to the decay of the plutonium heat source. In support of the DOE SRG project, the NASA Glenn Research Center (GRC) has established a technology effort to provide data to ensure a successful transition to flight for what will be the first dynamic power system in space. Initially, a limited number of areas were selected for the effort, however this is now being expanded to more thoroughly cover key technical issues. There is also an advanced technology effort that is complementary to the near-term technology effort. Many of the tests use the 55-We Technology Demonstration Convertor (TDC). There have been multiple controller tests to support the LMA flight controller design effort. Preparation is continuing for a thermal/vacuum system demonstration. A pair of flight prototype TDC s have been placed on continuous operation. Heater head life assessment continues, with the material data being refined and the analysis moving toward the system perspective. Magnet aging tests continue to characterize any possible aging in the strength or demagnetization resistance of the magnets in the linear alternator. A reliability effort has been initiated to help guide the development activities with focus on the key components and subsystems. This paper will provide an overview of some of the GRC technical efforts, including the status, and a description of future efforts.

  17. Approaches to a global quantum key distribution network

    NASA Astrophysics Data System (ADS)

    Islam, Tanvirul; Bedington, Robert; Ling, Alexander

    2017-10-01

    Progress in realising quantum computers threatens to weaken existing public key encryption infrastructure. A global quantum key distribution (QKD) network can play a role in computational attack-resistant encryption. Such a network could use a constellation of high altitude platforms such as airships and satellites as trusted nodes to facilitate QKD between any two points on the globe on demand. This requires both space-to-ground and inter-platform links. However, the prohibitive cost of traditional satellite based development limits the experimental work demonstrating relevant technologies. To accelerate progress towards a global network, we use an emerging class of shoe-box sized spacecraft known as CubeSats. We have designed a polarization entangled photon pair source that can operate on board CubeSats. The robustness and miniature form factor of our entanglement source makes it especially suitable for performing pathfinder missions that studies QKD between two high altitude platforms. The technological outcomes of such mission would be the essential building blocks for a global QKD network.

  18. Advanced optical components for next-generation photonic networks

    NASA Astrophysics Data System (ADS)

    Yoo, S. J. B.

    2003-08-01

    Future networks will require very high throughput, carrying dominantly data-centric traffic. The role of Photonic Networks employing all-optical systems will become increasingly important in providing scalable bandwidth, agile reconfigurability, and low-power consumptions in the future. In particular, the self-similar nature of data traffic indicates that packet switching and burst switching will be beneficial in the Next Generation Photonic Networks. While the natural conclusion is to pursue Photonic Packet Switching and Photonic Burst Switching systems, there are significant challenges in realizing such a system due to practical limitations in optical component technologies. Lack of a viable all-optical memory technology will continue to drive us towards exploring rapid reconfigurability in the wavelength domain. We will introduce and discuss the advanced optical component technologies behind the Photonic Packet Routing system designed and demonstrated at UC Davis. The system is capable of packet switching and burst switching, as well as circuit switching with 600 psec switching speed and scalability to 42 petabit/sec aggregated switching capacity. By utilizing a combination of rapidly tunable wavelength conversion and a uniform-loss cyclic frequency (ULCF) arrayed waveguide grating router (AWGR), the system is capable of rapidly switching the packets in wavelength, time, and space domains. The label swapping module inside the Photonic Packet Routing system containing a Mach-Zehnder wavelength converter and a narrow-band fiber Bragg-grating achieves all-optical label swapping with optical 2R (potentially 3R) regeneration while maintaining optical transparency for the data payload. By utilizing the advanced optical component technologies, the Photonic Packet Routing system successfully demonstrated error-free, cascaded, multi-hop photonic packet switching and routing with optical-label swapping. This paper will review the advanced optical component technologies

  19. Current Challenges for HTCMC Aero-Propulsion Components

    NASA Technical Reports Server (NTRS)

    DiCarlo, James A.; Bansal, Narottam P.

    2007-01-01

    In comparison to the best metallic materials, HTCMC aero-propulsion engine components offer the opportunity of reduced weight and higher temperature operation, with corresponding improvements in engine cooling requirements, emissions, thrust, and specific fuel consumption. Although much progress has been made in the development of advanced HTCMC constituent materials and processes, major challenges still remain for their implementation into these components. The objectives of this presentation are to briefly review (1) potential HTCMC aero-propulsion components and their generic material performance requirements, (2) recent progress at NASA and elsewhere concerning advanced constituents and processes for meeting these requirements, (3) key HTCMC component implementation challenges that are currently being encountered, and (4) on-going activities within the new NASA Fundamental Aeronautics Program that are addressing these challenges.

  20. The key to enabling biosurveillance is cooperative technology development.

    PubMed

    Emanuel, Peter; Jones, Franca; Smith, Michael; Huff, William; Jaffe, Richard; Roos, Jason

    2011-12-01

    The world population will continue to face biological threats, whether they are naturally occurring or intentional events. The speed with which diseases can emerge and spread presents serious challenges, because the impact on public health, the economy, and development can be huge. The U.S. government recognizes that global public health can also have an impact on national security. This global perspective manifests itself in U.S. policy documents that clearly articulate the importance of biosurveillance in providing early warning, detection, and situational awareness of infectious disease threats in order to mount a rapid response and save lives. In this commentary, we suggest that early recognition of infectious disease threats, whether naturally occurring or man-made, requires a globally distributed array of interoperable hardware and software fielded in sufficient numbers to create a network of linked collection nodes. We argue that achievement of this end state will require a degree of cooperation that does not exist at this time-either across the U.S. federal government or among our global partners. Successful fielding of a family of interoperable technologies will require interagency research, development, and purchase ("acquisition") of biosurveillance systems through cooperative ventures that likely will involve our strategic allies and public-private partnerships. To this end, we propose leveraging an existing federal interagency group to integrate the acquisition of technologies to enable global biosurveillance. © Mary Ann Liebert, Inc.

  1. Introducing an algal carbon-concentrating mechanism into higher plants: location and incorporation of key components.

    PubMed

    Atkinson, Nicky; Feike, Doreen; Mackinder, Luke C M; Meyer, Moritz T; Griffiths, Howard; Jonikas, Martin C; Smith, Alison M; McCormick, Alistair J

    2016-05-01

    Many eukaryotic green algae possess biophysical carbon-concentrating mechanisms (CCMs) that enhance photosynthetic efficiency and thus permit high growth rates at low CO2 concentrations. They are thus an attractive option for improving productivity in higher plants. In this study, the intracellular locations of ten CCM components in the unicellular green alga Chlamydomonas reinhardtii were confirmed. When expressed in tobacco, all of these components except chloroplastic carbonic anhydrases CAH3 and CAH6 had the same intracellular locations as in Chlamydomonas. CAH6 could be directed to the chloroplast by fusion to an Arabidopsis chloroplast transit peptide. Similarly, the putative inorganic carbon (Ci) transporter LCI1 was directed to the chloroplast from its native location on the plasma membrane. CCP1 and CCP2 proteins, putative Ci transporters previously reported to be in the chloroplast envelope, localized to mitochondria in both Chlamydomonas and tobacco, suggesting that the algal CCM model requires expansion to include a role for mitochondria. For the Ci transporters LCIA and HLA3, membrane location and Ci transport capacity were confirmed by heterologous expression and H(14) CO3 (-) uptake assays in Xenopus oocytes. Both were expressed in Arabidopsis resulting in growth comparable with that of wild-type plants. We conclude that CCM components from Chlamydomonas can be expressed both transiently (in tobacco) and stably (in Arabidopsis) and retargeted to appropriate locations in higher plant cells. As expression of individual Ci transporters did not enhance Arabidopsis growth, stacking of further CCM components will probably be required to achieve a significant increase in photosynthetic efficiency in this species. © 2015 The Authors. Plant Biotechnology Journal published by Society for Experimental Biology and The Association of Applied Biologists and John Wiley & Sons Ltd.

  2. Tag Content Access Control with Identity-based Key Exchange

    NASA Astrophysics Data System (ADS)

    Yan, Liang; Rong, Chunming

    2010-09-01

    Radio Frequency Identification (RFID) technology that used to identify objects and users has been applied to many applications such retail and supply chain recently. How to prevent tag content from unauthorized readout is a core problem of RFID privacy issues. Hash-lock access control protocol can make tag to release its content only to reader who knows the secret key shared between them. However, in order to get this shared secret key required by this protocol, reader needs to communicate with a back end database. In this paper, we propose to use identity-based secret key exchange approach to generate the secret key required for hash-lock access control protocol. With this approach, not only back end database connection is not needed anymore, but also tag cloning problem can be eliminated at the same time.

  3. Component-based target recognition inspired by human vision

    NASA Astrophysics Data System (ADS)

    Zheng, Yufeng; Agyepong, Kwabena

    2009-05-01

    In contrast with machine vision, human can recognize an object from complex background with great flexibility. For example, given the task of finding and circling all cars (no further information) in a picture, you may build a virtual image in mind from the task (or target) description before looking at the picture. Specifically, the virtual car image may be composed of the key components such as driver cabin and wheels. In this paper, we propose a component-based target recognition method by simulating the human recognition process. The component templates (equivalent to the virtual image in mind) of the target (car) are manually decomposed from the target feature image. Meanwhile, the edges of the testing image can be extracted by using a difference of Gaussian (DOG) model that simulates the spatiotemporal response in visual process. A phase correlation matching algorithm is then applied to match the templates with the testing edge image. If all key component templates are matched with the examining object, then this object is recognized as the target. Besides the recognition accuracy, we will also investigate if this method works with part targets (half cars). In our experiments, several natural pictures taken on streets were used to test the proposed method. The preliminary results show that the component-based recognition method is very promising.

  4. Packaging of structural health monitoring components

    NASA Astrophysics Data System (ADS)

    Kessler, Seth S.; Spearing, S. Mark; Shi, Yong; Dunn, Christopher T.

    2004-07-01

    Structural Health Monitoring (SHM) technologies have the potential to realize economic benefits in a broad range of commercial and defense markets. Previous research conducted by Metis Design and MIT has demonstrated the ability of Lamb waves methods to provide reliable information regarding the presence, location and type of damage in composite specimens. The present NSF funded program was aimed to study manufacturing, packaging and interface concepts for critical SHM components. The intention is to be able to cheaply manufacture robust actuating/sensing devices, and isolate them from harsh operating environments including natural, mechanical, or electrical extremes. Currently the issues related to SHM system durability have remained undressed. During the course of this research several sets of test devices were fabricated and packaged to protect the piezoelectric component assemblies for robust operation. These assemblies were then tested in hot and wet conditions, as well as in electrically noisy environments. Future work will aim to package the other supporting components such as the battery and wireless chip, as well as integrating all of these components together for operation. SHM technology will enable the reduction or complete elimination of scheduled inspections, and will allow condition-based maintenance for increased reliability and reduced overall life-cycle costs.

  5. Keys and seats: Spatial response coding underlying the joint spatial compatibility effect.

    PubMed

    Dittrich, Kerstin; Dolk, Thomas; Rothe-Wulf, Annelie; Klauer, Karl Christoph; Prinz, Wolfgang

    2013-11-01

    Spatial compatibility effects (SCEs) are typically observed when participants have to execute spatially defined responses to nonspatial stimulus features (e.g., the color red or green) that randomly appear to the left and the right. Whereas a spatial correspondence of stimulus and response features facilitates response execution, a noncorrespondence impairs task performance. Interestingly, the SCE is drastically reduced when a single participant responds to one stimulus feature (e.g., green) by operating only one response key (individual go/no-go task), whereas a full-blown SCE is observed when the task is distributed between two participants (joint go/no-go task). This joint SCE (a.k.a. the social Simon effect) has previously been explained by action/task co-representation, whereas alternative accounts ascribe joint SCEs to spatial components inherent in joint go/no-go tasks that allow participants to code their responses spatially. Although increasing evidence supports the idea that spatial rather than social aspects are responsible for joint SCEs emerging, it is still unclear to which component(s) the spatial coding refers to: the spatial orientation of response keys, the spatial orientation of responding agents, or both. By varying the spatial orientation of the responding agents (Exp. 1) and of the response keys (Exp. 2), independent of the spatial orientation of the stimuli, in the present study we found joint SCEs only when both the seating and the response key alignment matched the stimulus alignment. These results provide evidence that spatial response coding refers not only to the response key arrangement, but also to the-often neglected-spatial orientation of the responding agents.

  6. Body of Knowledge (BOK) for Leadless Quad Flat No-Lead/bottom Termination Components (QFN/BTC) Package Trends and Reliability

    NASA Technical Reports Server (NTRS)

    Ghaffarian, Reza

    2014-01-01

    Bottom terminated components and quad flat no-lead (BTC/QFN) packages have been extensively used by commercial industry for more than a decade. Cost and performance advantages and the closeness of the packages to the boards make them especially unique for radio frequency (RF) applications. A number of high-reliability parts are now available in this style of package configuration. This report presents a summary of literature surveyed and provides a body of knowledge (BOK) gathered on the status of BTC/QFN and their advanced versions of multi-row QFN (MRQFN) packaging technologies. The report provides a comprehensive review of packaging trends and specifications on design, assembly, and reliability. Emphasis is placed on assembly reliability and associated key design and process parameters because they show lower life than standard leaded package assembly under thermal cycling exposures. Inspection of hidden solder joints for assuring quality is challenging and is similar to ball grid arrays (BGAs). Understanding the key BTC/QFN technology trends, applications, processing parameters, workmanship defects, and reliability behavior is important when judicially selecting and narrowing the follow-on packages for evaluation and testing, as well as for the low risk insertion in high-reliability applications.

  7. Body of Knowledge (BOK) for Leadless Quad Flat No-Lead/Bottom Termination Components (QFN/BTC) Package Trends and Reliability

    NASA Technical Reports Server (NTRS)

    Ghaffarian, Reza

    2014-01-01

    Bottom terminated components and quad flat no-lead (BTC/QFN) packages have been extensively used by commercial industry for more than a decade. Cost and performance advantages and the closeness of the packages to the boards make them especially unique for radio frequency (RF) applications. A number of high-reliability parts are now available in this style of package configuration. This report presents a summary of literature surveyed and provides a body of knowledge (BOK) gathered on the status of BTC/QFN and their advanced versions of multi-row QFN (MRQFN) packaging technologies. The report provides a comprehensive review of packaging trends and specifications on design, assembly, and reliability. Emphasis is placed on assembly reliability and associated key design and process parameters because they show lower life than standard leaded package assembly under thermal cycling exposures. Inspection of hidden solder joints for assuring quality is challenging and is similar to ball grid arrays (BGAs). Understanding the key BTC/QFN technology trends, applications, processing parameters, workmanship defects, and reliability behavior is important when judicially selecting and narrowing the follow-on packages for evaluation and testing, as well as for the low risk insertion in high-reliability applications.

  8. Technology Assessment for Powertrain Components Final Report CRADA No. TC-1124-95

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tokarz, F.; Gough, C.

    LLNL utilized its defense technology assessment methodologies in combination with its capabilities in the energy; manufacturing, and transportation technologies to demonstrate a methodology that synthesized available but incomplete information on advanced automotive technologies into a comprehensive framework.

  9. Weighted Components of i-Government Enterprise Architecture

    NASA Astrophysics Data System (ADS)

    Budiardjo, E. K.; Firmansyah, G.; Hasibuan, Z. A.

    2017-01-01

    Lack of government performance, among others due to the lack of coordination and communication among government agencies. Whilst, Enterprise Architecture (EA) in the government can be use as a strategic planning tool to improve productivity, efficiency, and effectivity. However, the existence components of Government Enterprise Architecture (GEA) do not show level of importance, that cause difficulty in implementing good e-government for good governance. This study is to explore the weight of GEA components using Principal Component Analysis (PCA) in order to discovered an inherent structure of e-government. The results show that IT governance component of GEA play a major role in the GEA. The rest of components that consist of e-government system, e-government regulation, e-government management, and application key operational, contributed more or less the same. Beside that GEA from other countries analyzes using comparative base on comon enterprise architecture component. These weighted components use to construct i-Government enterprise architecture. and show the relative importance of component in order to established priorities in developing e-government.

  10. Development of Manufacturing Technology to Accelerate Cost Reduction of Low Concentration and

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Detrick, Adam

    The purpose of this project was to accelerate deployment of cost-effective US-based manufacturing of Solaria’s unique c-Si module technology. This effort successfully resulted in the development of US-based manufacturing technology to support two highly-differentiated, market leading product platforms. The project was initially predicated on developing Solaria’s low-concentration PV (LCPV) module technology which at the time of the award was uniquely positioned to exceed the SunShot price goal of $0.50/Wp for standard c-Si modules. The Solaria LCPV module is a 2.5x concentrator that leverages proven, high-reliability PV module materials and low silicon cell usage into a technology package that already hadmore » the lowest direct material cost and leading Levelized Cost of Electricity (LCOE). With over 25 MW commercially deployed globally, the Solaria module was well positioned to continue to lead in PV module cost reduction. Throughout the term of the contract, market conditions changed dramatically and so to did Solaria’s product offerings to support this. However, the manufacturing technology developed for the LCPV module was successfully leveraged and optimized to support two new and different product platforms. BIPV “PowerVision” and High-efficiency “PowerXT” modules. The primary barrier to enabling high-volume PV module manufacturing in the US is the high manual labor component in certain unique aspects of our manufacturing process. The funding was used to develop unique manufacturing automation which makes the manual labor components of these key processes more efficient and increase throughput. At the core of Solaria’s product offerings are its unique and proprietary techniques for dicing and re-arranging solar cells into modules with highly-differentiated characteristics that address key gaps in the c-Si market. It is these techniques that were successfully evolved and deployed into US-based manufacturing site with SunShot funding. Today

  11. Key issues and technical route of cyber physical distribution system

    NASA Astrophysics Data System (ADS)

    Zheng, P. X.; Chen, B.; Zheng, L. J.; Zhang, G. L.; Fan, Y. L.; Pei, T.

    2017-01-01

    Relying on the National High Technology Research and Development Program, this paper introduced the key issues in Cyber Physical Distribution System (CPDS), mainly includes: composite modelling method and interaction mechanism, system planning method, security defence technology, distributed control theory. Then on this basis, the corresponding technical route is proposed, and a more detailed research framework along with main schemes to be adopted is also presented.

  12. Efficient multiparty quantum key agreement with collective detection.

    PubMed

    Huang, Wei; Su, Qi; Liu, Bin; He, Yuan-Hang; Fan, Fan; Xu, Bing-Jie

    2017-11-10

    As a burgeoning branch of quantum cryptography, quantum key agreement is a kind of key establishing processes where the security and fairness of the established common key should be guaranteed simultaneously. However, the difficulty on designing a qualified quantum key agreement protocol increases significantly with the increase of the number of the involved participants. Thus far, only few of the existing multiparty quantum key agreement (MQKA) protocols can really achieve security and fairness. Nevertheless, these qualified MQKA protocols are either too inefficient or too impractical. In this paper, an MQKA protocol is proposed with single photons in travelling mode. Since only one eavesdropping detection is needed in the proposed protocol, the qubit efficiency and measurement efficiency of it are higher than those of the existing ones in theory. Compared with the protocols which make use of the entangled states or multi-particle measurements, the proposed protocol is more feasible with the current technologies. Security and fairness analysis shows that the proposed protocol is not only immune to the attacks from external eavesdroppers, but also free from the attacks from internal betrayers.

  13. Satellite lidar and radar: Key components of the future climate observing system

    NASA Astrophysics Data System (ADS)

    Winker, D. M.

    2017-12-01

    Cloud feedbacks represent the dominant source of uncertainties in estimates of climate sensitivity and aerosols represent the largest source of uncertainty in climate forcing. Both observation of long-term changes and observational constraints on the processes responsible for those changes are necessary. The existing 30-year record of passive satellite observations has not yet provided constraints to significantly reduce these uncertainties, though. We now have more than a decade of experience with active sensors flying in the A-Train. These new observations have demonstrated the strengths of active sensors and the benefits of continued and more advanced active sensors. This talk will discuss the multiple roles for active sensors as an essential component of a global climate observing system.

  14. Reverse osmosis desalination: water sources, technology, and today's challenges.

    PubMed

    Greenlee, Lauren F; Lawler, Desmond F; Freeman, Benny D; Marrot, Benoit; Moulin, Philippe

    2009-05-01

    Reverse osmosis membrane technology has developed over the past 40 years to a 44% share in world desalting production capacity, and an 80% share in the total number of desalination plants installed worldwide. The use of membrane desalination has increased as materials have improved and costs have decreased. Today, reverse osmosis membranes are the leading technology for new desalination installations, and they are applied to a variety of salt water resources using tailored pretreatment and membrane system design. Two distinct branches of reverse osmosis desalination have emerged: seawater reverse osmosis and brackish water reverse osmosis. Differences between the two water sources, including foulants, salinity, waste brine (concentrate) disposal options, and plant location, have created significant differences in process development, implementation, and key technical problems. Pretreatment options are similar for both types of reverse osmosis and depend on the specific components of the water source. Both brackish water and seawater reverse osmosis (RO) will continue to be used worldwide; new technology in energy recovery and renewable energy, as well as innovative plant design, will allow greater use of desalination for inland and rural communities, while providing more affordable water for large coastal cities. A wide variety of research and general information on RO desalination is available; however, a direct comparison of seawater and brackish water RO systems is necessary to highlight similarities and differences in process development. This article brings to light key parameters of an RO process and process modifications due to feed water characteristics.

  15. Aerospace and Flight. Technology Learning Activity. Teacher Edition. Technology Education Series.

    ERIC Educational Resources Information Center

    Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

    This packet of technology learning activity (TLA) materials on aerospace and flight for students in grades 6-10 consists of a technology education overview, information on use, and instructor's and student's sections. The overview discusses the technology education program and materials. Components of the instructor's and student's sections are…

  16. Introduction to Animation. Technology Learning Activity. Teacher Edition. Technology Education Series.

    ERIC Educational Resources Information Center

    Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

    This packet of technology learning activity (TLA) materials on introduction to animation for students in grades 6-10 consists of a technology education overview, information on use, and the instructor's and student's sections. The overview discusses the technology education program and materials. Section components are described next. The…

  17. Discrete Event Simulation Modeling and Analysis of Key Leader Engagements

    DTIC Science & Technology

    2012-06-01

    to offer. GreenPlayer agents require four parameters, pC, pKLK, pTK, and pRK , which give probabilities for being corrupt, having key leader...HandleMessageRequest component. The same parameter constraints apply to these four parameters. The parameter pRK is the same parameter from the CreatePlayers component...whether the local Green player has resource critical knowledge by using the parameter pRK . It schedules an EndResourceKnowledgeRequest event, passing

  18. Advanced Technology Lifecycle Analysis System (ATLAS) Technology Tool Box (TTB)

    NASA Technical Reports Server (NTRS)

    Doyle, Monica; ONeil, Daniel A.; Christensen, Carissa B.

    2005-01-01

    The Advanced Technology Lifecycle Analysis System (ATLAS) is a decision support tool designed to aid program managers and strategic planners in determining how to invest technology research and development dollars. It is an Excel-based modeling package that allows a user to build complex space architectures and evaluate the impact of various technology choices. ATLAS contains system models, cost and operations models, a campaign timeline and a centralized technology database. Technology data for all system models is drawn from a common database, the ATLAS Technology Tool Box (TTB). The TTB provides a comprehensive, architecture-independent technology database that is keyed to current and future timeframes.

  19. Acadia National Park ITS field operational test : key informant interviews

    DOT National Transportation Integrated Search

    2003-03-01

    This document reflects the ideas and opinions of a group of key informants and stakeholders involved in the Field Operational Test of ITS components in and around Acadia National Park from 1999 through 2002. The stakeholders were involved in the plan...

  20. Integrated quantum key distribution sender unit for daily-life implementations

    NASA Astrophysics Data System (ADS)

    Mélen, Gwenaelle; Vogl, Tobias; Rau, Markus; Corrielli, Giacomo; Crespi, Andrea; Osellame, Roberto; Weinfurter, Harald

    2016-03-01

    Unlike currently implemented encryption schemes, Quantum Key Distribution provides a secure way of generating and distributing a key among two parties. Although a multitude of research platforms has been developed, the integration of QKD units within classical communication systems remains a tremendous challenge. The recently achieved maturity of integrated photonic technologies could be exploited to create miniature QKD add-ons that could extend the primary function of various existing systems such as mobile devices or optical stations. In this work we report on an integrated optics module enabling secure short-distance communication for, e.g., quantum access schemes. Using BB84-like protocols, Alice's mobile low-cost device can exchange secure key and information everywhere within a trusted node network. The new optics platform (35×20×8mm) compatible with current smartphone's technology generates NIR faint polarised laser pulses with 100MHz repetition rate. Fully automated beam tracking and live basis-alignment on Bob's side ensure user-friendly operation with a quantum link efficiency as high as 50% stable over a few seconds.