Sample records for key technology drivers

  1. SPIDER: A Framework for Understanding Driver Distraction.

    PubMed

    Strayer, David L; Fisher, Donald L

    2016-02-01

    The objective was to identify key cognitive processes that are impaired when drivers divert attention from driving. Driver distraction is increasingly recognized as a significant source of injuries and fatalities on the roadway. A "SPIDER" model is developed that identifies key cognitive processes that are impaired when drivers divert attention from driving. SPIDER is an acronym standing for scanning, predicting, identifying, decision making, and executing a response. When drivers engage in secondary activities unrelated to the task of driving, SPIDER-related processes are impaired, situation awareness is degraded, and the ability to safely operate a motor vehicle may be compromised. The pattern of interference helps to illuminate the sources of driver distraction and may help guide the integration of new technology into the automobile. © 2015, Human Factors and Ergonomics Society.

  2. Industry Training: Causes and Consequences.

    ERIC Educational Resources Information Center

    Smith, Andrew; Freeland, Brett

    Research on Australian organizations in five industry sectors--building and construction, food processing, electronics manufacturing, retailing, and finance and banking--has identified these three key drivers of enterprise training: workplace change, quality assurance, and new technology. Operation of the training drivers is moderated by a range…

  3. Optimization of shared autonomy vehicle control architectures for swarm operations.

    PubMed

    Sengstacken, Aaron J; DeLaurentis, Daniel A; Akbarzadeh-T, Mohammad R

    2010-08-01

    The need for greater capacity in automotive transportation (in the midst of constrained resources) and the convergence of key technologies from multiple domains may eventually produce the emergence of a "swarm" concept of operations. The swarm, which is a collection of vehicles traveling at high speeds and in close proximity, will require technology and management techniques to ensure safe, efficient, and reliable vehicle interactions. We propose a shared autonomy control approach, in which the strengths of both human drivers and machines are employed in concert for this management. Building from a fuzzy logic control implementation, optimal architectures for shared autonomy addressing differing classes of drivers (represented by the driver's response time) are developed through a genetic-algorithm-based search for preferred fuzzy rules. Additionally, a form of "phase transition" from a safe to an unsafe swarm architecture as the amount of sensor capability is varied uncovers key insights on the required technology to enable successful shared autonomy for swarm operations.

  4. Flexible Pedagogies: Technology-Enhanced Learning. Flexible Pedagogies: Preparing for the Future Series

    ERIC Educational Resources Information Center

    Gordon, Neil

    2014-01-01

    This publication is part of our five-strand research project "Flexible Pedagogies: preparing for the future". It focuses on a better understanding of technology-enhanced learning (TEL) and: (1) identifies key international drivers in the move towards technology-enhanced learning; (2) highlights some of the challenges and opportunities…

  5. A 10 Gb/s laser driver in 130 nm CMOS technology for high energy physics applications

    DOE PAGES

    Zhang, T.; Tavernier, F.; Moreira, P.; ...

    2015-02-19

    The GigaBit Laser Driver (GBLD) is a key on-detector component of the GigaBit Transceiver (GBT) system at the transmitter side. We have developed a 10 Gb/s GBLD (GBLD10) in a 130 nm CMOS technology, as part of the design efforts towards the upgrade of the electrical components of the LHC experiments. The GBLD10 is based on the distributed-amplifier (DA) architecture and achieves data rates up to 10 Gb/s. It is capable of driving VCSELs with modulation currents up to 12 mA. Furthermore, a pre-emphasis function has been included in the proposed laser driver in order to compensate for the capacitivemore » load and channel losses.« less

  6. Research Universities, Technology Transfer, and Job Creation: What Infrastructure, For What Training?

    ERIC Educational Resources Information Center

    Brodhag, Christian

    2013-01-01

    Technology transfer and innovation are considered major drivers of sustainable development; they place knowledge and its dissemination in society at the heart of the development process. This article considers the role of research universities, and how they can interact with key actors and institutions involved in "innovation…

  7. Medical technology as a key driver of rising health expenditure: disentangling the relationship

    PubMed Central

    Sorenson, Corinna; Drummond, Michael; Bhuiyan Khan, Beena

    2013-01-01

    Health care spending has risen steadily in most countries, becoming a concern for decision-makers worldwide. Commentators often point to new medical technology as the key driver for burgeoning expenditures. This paper critically appraises this conjecture, based on an analysis of the existing literature, with the aim of offering a more detailed and considered analysis of this relationship. Several databases were searched to identify relevant literature. Various categories of studies (eg, multivariate and cost-effectiveness analyses) were included to cover different perspectives, methodological approaches, and issues regarding the link between medical technology and costs. Selected articles were reviewed and relevant information was extracted into a standardized template and analyzed for key cross-cutting themes, ie, impact of technology on costs, factors influencing this relationship, and methodological challenges in measuring such linkages. A total of 86 studies were reviewed. The analysis suggests that the relationship between medical technology and spending is complex and often conflicting. Findings were frequently contingent on varying factors, such as the availability of other interventions, patient population, and the methodological approach employed. Moreover, the impact of technology on costs differed across technologies, in that some (eg, cancer drugs, invasive medical devices) had significant financial implications, while others were cost-neutral or cost-saving. In light of these issues, we argue that decision-makers and other commentators should extend their focus beyond costs solely to include consideration of whether medical technology results in better value in health care and broader socioeconomic benefits. PMID:23807855

  8. Travel time on arterials and rural highways : state-of-the-practice synthesis on rural data collection technology.

    DOT National Transportation Integrated Search

    2013-04-01

    "Travel time to a destination is a key piece of information that motorists want and need, and is vital for good decision-making by travelers. Technology now makes it feasible to provide drivers with real-time information about how long it takes to re...

  9. Remarks to SBS PCM based self-navigation of laser drivers

    NASA Astrophysics Data System (ADS)

    Kalal, M.; Matena, L.; Kong, HJ; Martinkova, M.; Cha, S.

    2016-03-01

    A novel technology of self-navigation of laser drivers on injected inertial fusion energy pellets employing phase conjugating mirrors based on stimulating Brillouin scattering was recently proposed. Its feasibility as well as various implications were gradually studied and working solutions to potential problems were always suggested. As this technology could help to overcome several burning key issues of inertial fusion (e.g., a sufficiently precise navigation of laser drivers on injected pellets in the case of a direct drive scheme and decreased requirements on high-repetition high-power lasers) it gradually started to attract a carefully measured tentative interest among the major inertial fusion oriented laboratories and projects. In this paper the next step in this research path will be reported. It concerns the resulting phase and amplitude structures created by multiple low energy drivers (glints) illuminating the pellet during the first stage of the process after their reflection and a subsequent superposition on the collecting/focusing final optics. It was demonstrated that with a large number of such drivers acting simultaneously from many angles the situation gets somewhat complicated and requires more detailed studies/suggestions of suitable configurations.

  10. Toward best practice in Human Machine Interface design for older drivers: A review of current design guidelines.

    PubMed

    Young, K L; Koppel, S; Charlton, J L

    2017-09-01

    Older adults are the fastest growing segment of the driving population. While there is a strong emphasis for older people to maintain their mobility, the safety of older drivers is a serious community concern. Frailty and declines in a range of age-related sensory, cognitive, and physical impairments can place older drivers at an increased risk of crash-related injuries and death. A number of studies have indicated that in-vehicle technologies such as Advanced Driver Assistance Systems (ADAS) and In-Vehicle Information Systems (IVIS) may provide assistance to older drivers. However, these technologies will only benefit older drivers if their design is congruent with the complex needs and diverse abilities of this driving cohort. The design of ADAS and IVIS is largely informed by automotive Human Machine Interface (HMI) guidelines. However, it is unclear to what extent the declining sensory, cognitive and physical capabilities of older drivers are addressed in the current guidelines. This paper provides a review of key current design guidelines for IVIS and ADAS with respect to the extent they address age-related changes in functional capacities. The review revealed that most of the HMI guidelines do not address design issues related to older driver impairments. In fact, in many guidelines driver age and sensory cognitive and physical impairments are not mentioned at all and where reference is made, it is typically very broad. Prescriptive advice on how to actually design a system so that it addresses the needs and limitations of older drivers is not provided. In order for older drivers to reap the full benefits that in-vehicle technology can afford, it is critical that further work establish how older driver limitations and capabilities can be supported by the system design process, including their inclusion into HMI design guidelines. Copyright © 2016 Elsevier Ltd. All rights reserved.

  11. Understanding the underlying drivers of inpatient cost growth: a literature review.

    PubMed

    Goetghebeur, Mireille M; Forrest, Sharon; Hay, Joel W

    2003-06-01

    After the declining growth in inpatient hospital spending that occurred from 1994 through 1998, the recent trend in increased spending has been of concern to many. Understanding the underlying reasons for this new growth will aid decision makers in finding best means to manage inpatient costs. To identify potential contributors to recent growth in inpatient spending. Literature review. Healthcare and economic databases, prominent Web sites, and key journals were searched to identify potential drivers for the 1999-2001 rise in inpatient spending. Initial literature review and state-level regression analyses published in a companion paper were used to identify key explanatory factors, which were further explored. Although many of the contributors to the rise in inpatient costs overlap and are interrelated, the major cost drivers were identified as (1) workforce shortage; (2) new technology; (3) less tightly managed care; and (4) shifting hospital business directions. Underlying factors such as legislation, quality of care, limited access to noninpatient care, pressures on the safety net, population aging, and increasing chronic illness prevalence were found to influence the contributors and healthcare spending in general. Future trends in inpatient spending will depend on the response of the healthcare system to these cost drivers and underlying factors. Potential avenues to control inpatient spending include expanding access to primary care, encouraging cost-effective technology and more efficient hospital market structures, and developing incentives for the healthcare workforce.

  12. Competition for land

    PubMed Central

    Smith, Pete; Gregory, Peter J.; van Vuuren, Detlef; Obersteiner, Michael; Havlík, Petr; Rounsevell, Mark; Woods, Jeremy; Stehfest, Elke; Bellarby, Jessica

    2010-01-01

    A key challenge for humanity is how a future global population of 9 billion can all be fed healthily and sustainably. Here, we review how competition for land is influenced by other drivers and pressures, examine land-use change over the past 20 years and consider future changes over the next 40 years. Competition for land, in itself, is not a driver affecting food and farming in the future, but is an emergent property of other drivers and pressures. Modelling studies suggest that future policy decisions in the agriculture, forestry, energy and conservation sectors could have profound effects, with different demands for land to supply multiple ecosystem services usually intensifying competition for land in the future. In addition to policies addressing agriculture and food production, further policies addressing the primary drivers of competition for land (population growth, dietary preference, protected areas, forest policy) could have significant impacts in reducing competition for land. Technologies for increasing per-area productivity of agricultural land will also be necessary. Key uncertainties in our projections of competition for land in the future relate predominantly to uncertainties in the drivers and pressures within the scenarios, in the models and data used in the projections and in the policy interventions assumed to affect the drivers and pressures in the future. PMID:20713395

  13. An observational study of driving distractions on urban roads in Spain.

    PubMed

    Prat, F; Planes, M; Gras, M E; Sullman, M J M

    2015-01-01

    The present research investigated the prevalence of driver engagement in secondary tasks and whether there were any differences by age and gender, as well as day of the week and time of the day. Two independent researchers observed 6578 drivers at nine randomly selected urban locations in Girona, Spain. Nearly 20% of the drivers observed were engaged in some type of secondary task, with the most common being: conversing with a passenger (11.1%), smoking (3.7%) and talking on a handheld mobile phone (1.3%). Surprisingly there were no differences by gender, but there were age-related differences with younger drivers being more frequently observed engaged in a number of different types of secondary tasks while driving (i.e. drinking, talking on a handheld mobile phone, and texting or keying numbers). Logistic regression showed that younger drivers, and to a lesser extent middle-age drivers, were significantly more likely to be observed engaged in a technological distraction than older drivers. Conversely, non-technological distractions were significantly predicted by day of the week, time of the day and location. A substantial number of the drivers observed in this study were putting themselves at an increased risk of becoming involved in a crash by engaging in non-driving related tasks at the same time as driving. Furthermore, the higher crash rate among young drivers may be partially accounted for by their more frequent engagement in some types of secondary tasks while driving. Copyright © 2014. Published by Elsevier Ltd.

  14. Web 2.0 and the Impact of ICT Fuelled Participatory Culture in Rural and Remote Education: (SPERA Keynote 2009 Conference Address)

    ERIC Educational Resources Information Center

    Anderson, Neil

    2009-01-01

    This paper and presentation reviews the collective opinion of key Australian researchers concerning the emerging technologies most likely to have a significant impact on learning and teaching in regional, rural and remote areas. It then draws on the conclusions of the Horizon Report (2008) concerning key ICT drivers likely to influence…

  15. Environmental control and life support system requirements and technology needs for advanced manned space missions

    NASA Technical Reports Server (NTRS)

    Powell, Ferolyn T.; Sedej, Melaine; Lin, Chin

    1987-01-01

    NASA has completed an environmental control and life support system (ECLSS) technology R&D plan for advanced missions which gave attention to the drivers (crew size, mission duration, etc.) of a range of manned missions under consideration. Key planning guidelines encompassed a time horizon greater than 50 years, funding resource requirements, an evolutionary approach to goal definition, and the funding of more than one approach to satisfy a given perceived requirement. Attention was given to the ECLSS requirements of transportation and service vehicles, platforms, bases and settlements, ECLSS functions and average load requirements, unique drivers for various missions, and potentially exploitable commonalities among vehicles and habitats.

  16. Incorporating Grasslands into Cropping Systems: What are the Keys?

    USDA-ARS?s Scientific Manuscript database

    American agriculture in the 20th century has been shaped by social/political, economic, environmental and technological drivers. During this time, American agricultural systems became increasingly specialized and input driven resulting in agricultural production being dominated by ‘commodity crop p...

  17. Evaluating Online Media Literacy in Higher Education: Validity and Reliability of the Digital Online Media Literacy Assessment (DOMLA)

    ERIC Educational Resources Information Center

    Hallaq, Thomas G.

    2013-01-01

    While new technology continues to develop and become increasingly affordable, and students have increased access to electronic media, one might wonder if requiring such technology in the classroom is akin to throwing the car keys to a teen-ager who has not completed a driver's education course. Currently, no validated survey has been created…

  18. Evaluating Online Media Literacy in Higher Education: Validity and Reliability of the Digital Online Media Literacy Assessment (DOMLA)

    ERIC Educational Resources Information Center

    Hallaq, Tom

    2016-01-01

    While new technology continues to develop and become increasingly affordable, and students have increased access to digital media, one might wonder if requiring such technology in the classroom is akin to throwing the car keys to a teenager who has not completed a driver's education course. The purpose of this study was to develop a valid and…

  19. Technology Evaluation and Integration for Heavy Tactical Vehicles

    DTIC Science & Technology

    2010-08-17

    for Movie - May have to Exit slide show mode UNCLASSIFIED Key Findings- Modular Hydraulic Powered Generator • Hydraulic powered alternator proved...for Movie - May have to Exit slide show mode UNCLASSIFIED PPMS Key Findings Findings: • Hybrid starting system proved functional • Works with wide...to compute inter- vehicle closing distance & stopping time. • Provide audible/visual alert to driver inside their reaction time window. • Use COTS

  20. Drivers of sustained hygiene behaviour change: A case study from mid-western Nepal.

    PubMed

    McMichael, Celia; Robinson, Priscilla

    2016-08-01

    Behaviour change is central to the prevention of many population health problems, yet it is typically difficult to initiate and sustain. This paper reports on an evaluation of a water, sanitation and hygiene (WASH) intervention in mid-western Nepal, with particular focus on the drivers and barriers for handwashing with soap/ash and elimination of open defecation. The research was conducted during October-November 2014, two and half years following the intervention's end-point. Qualitative data were collected from the target community (n = 112) via group discussions, interviews and drawings/stories of 'most significant change'. Households' handwashing/water facilities and toilets were observed. Analysis was informed by a model that highlights environmental, psychosocial and technological factors that shape hygiene behaviours across multiple levels, from the habitual to the structural (Dreibelbis et al. 2013). Findings indicate the intervention has supported development of new norms around hygiene behaviours. Key drivers of sustained hygiene behaviour were habit formation, emotional drivers (e.g. disgust, affiliation), and collective action and civic pride; key constraints included water scarcity and socio-economic disadvantage. Identifying and responding to the drivers and constraints of hygiene behaviour change in specific contexts is critical to sustained behaviour change and population health impact. Copyright © 2016 Elsevier Ltd. All rights reserved.

  1. Technology and teen drivers.

    PubMed

    Lee, John D

    2007-01-01

    The rapid evolution of computing, communication, and sensor technology is likely to affect young drivers more than others. The distraction potential of infotainment technology stresses the same vulnerabilities that already lead young drivers to crash more frequently than other drivers. Cell phones, text messaging, MP3 players, and other nomadic devices all present a threat because young drivers may lack the spare attentional capacity for vehicle control and the ability to anticipate and manage hazards. Moreover, young drivers are likely to be the first and most aggressive users of new technology. Fortunately, emerging technology can also support safe driving. Electronic stability control, collision avoidance systems, intelligent speed adaptation, and vehicle tracking systems can all help mitigate the threats to young drivers. However, technology alone is unlikely to make young drivers safer. One promising approach to tailoring technology to teen drivers is to extend proven methods for enhancing young driver safety. The success of graduated drivers license programs (GDL) and the impressive safety benefit of supervised driving suggest ways of tailoring technology to the needs of young drivers. To anticipate the effects of technology on teen driving it may be useful to draw an analogy between the effects of passengers and the effects of technology. Technology can act as a teen passenger and undermine safety or it can act as an adult passenger and enhance safety. Rapidly developing technology may have particularly large effects on teen drivers. To maximize the positive effects and minimize the negative effects will require a broad range of industries to work together. Ideally, vehicle manufacturers would work with infotainment providers, insurance companies, and policy makers to craft new technologies so that they accommodate the needs of young drivers. Without such collaboration young drivers will face even greater challenges to their safety as new technologies emerge.

  2. To delegate or not to delegate: A review of control frameworks for autonomous cars.

    PubMed

    Richards, Dale; Stedmon, Alex

    2016-03-01

    There have been significant advances in technology and automated systems that will eventually see the use of autonomous cars as commonplace on our roads. Various systems are already available that provide the driver with different levels of decision support. This paper highlights the key human factors issues associated with the interaction between the user and an autonomous system, including assistive decision support and the delegation of authority to the automobile. The level of support offered to the driver can range from traditional automated assistance, to system generated guidance that offers advice for the driver to act upon, and even more direct action that is initiated by the system itself without driver intervention. In many of these instances the role of the driver is slowly moving towards a supervisory role within a complex system rather than one of direct control of the vehicle. Different paradigms of interaction are considered and focus is placed on the partnership that takes place between the driver and the vehicle. Drawing on the wealth of knowledge that exists within the aviation domain and research literature that examines technology partnerships within the cockpit, this paper considers important factors that will assist the automotive community to understand the underlying issues of the human and their interaction within complex systems. Copyright © 2015 Elsevier Ltd and The Ergonomics Society. All rights reserved.

  3. Driver development of IFE power plant in Japan Collaborative process with industry and industrial applications

    NASA Astrophysics Data System (ADS)

    Nakai, S.; Yamanaka, M.; Kitagawa, Y.; Fujita, K.; Heya, M.; Mima, K.; Izawa, Y.; Nakatsuka, M.; Murakami, M.; Ueda, K.; Sasaki, T.; Mori, Y.; Kanabe, T.; Hiruma, T.; Kan, H.; Kawashima, T.

    2006-06-01

    The typical specifications of the laser driver for a commercial IFE power plant are (1) total energy (MJ/pulse) with a tailored 20-40 ns pulse, (2) repetition operation (˜ 10 Hz), (3) efficiency (˜ 10%) with enough robustness and low cost. The key elements of the DPSSL driver technology are under development with HALNA. The HALNA 10 (High Average-power Laser for Nuclear-fusion Application) demonstrated 10 J × 10 Hz operation and the HALNA 100 (100 J × 10 Hz) is now under construction. By using the high average power and high intensity lasers, new industrial applications are being proceeded. The collaborative process for the development of high power laser with industry and for the industrial applications is effective and essential in the development of the laser driver for IFE power plant.

  4. What's the Use of a VLE?

    ERIC Educational Resources Information Center

    O'Rourke, Kevin C.; Rooney, Pauline; Boylan, Frances

    2015-01-01

    Virtual Learning Environments (VLEs) have become an integral part of the technological furniture of higher education over the past two decades. While some VLE adopters have argued that the enhancement of teaching and learning is a key driver underpinning their use, an increasing number have described typical VLE usage as a "notes-bank…

  5. Challenges in Aeropropulsion

    NASA Technical Reports Server (NTRS)

    Campbell, Donald C.

    1995-01-01

    Aeropropulsion technologies must progress to satisfy increasingly stringent global environmental requirements with economically viable air transportation systems. In this paper, key propulsion technologies to meet future needs are identified and the associated challenges are briefly discussed. Also discussed are NASA's vision, NASA's changing role in meeting today's challenge of a shrinking research budget, and propulsion technology impacts on the environment and air transport economics. Critical aeropropulsion technology drivers are identified and their impact evaluated. The aviation industry is critical to the nation's economy, job creation, and national security. NASA's advanced aeropropulsion technology programs and their relation to the aviation industry are discussed.

  6. Mission Architecture and Technology Options for a Flagship Class Venus In Situ Mission

    NASA Technical Reports Server (NTRS)

    Balint, Tibor S.; Kwok, Johnny H.; Kolawa, Elizabeth A.; Cutts, James A.; Senske, David A.

    2008-01-01

    Venus, as part of the inner triad with Earth and Mars, represents an important exploration target if we want to learn more about solar system formation and evolution. Comparative planetology could also elucidate the differences between the past, present, and future of these three planets, and can help with the characterization of potential habitable zones in our solar system and, by extension, extrasolar systems. A long lived in situ Venus mission concept, called the Venus Mobile Explorer, was prominently featured in NASA's 2006 SSE Roadmap and supported in the community White Paper by the Venus Exploration Analysis Group (VEXAG). Long-lived in situ missions are expected to belong to the largest (Flagship) mission class, which would require both enabling and enhancing technologies beside mission architecture options. Furthermore, extreme environment mitigation technologies for Venus are considered long lead development items and are expected to require technology development through a dedicated program. To better understand programmatic and technology needs and the motivating science behind them, in this fiscal year (FY08) NASA is funding a Venus Flaghip class mission study, based on key science and technology drivers identified by a NASA appointed Venus Science and Technology Definition Team (STDT). These mission drivers are then assembled around a suitable mission architecture to further refine technology and cost elements. In this paper we will discuss the connection between the final mission architecture and the connected technology drivers from this NASA funded study, which - if funded - could enable a future Flagship class Venus mission and potentially drive a proposed Venus technology development program.

  7. Exploring Challenges in Developing a Smart and Effective Assistive System for Improving the Experience of the Elderly Drivers

    NASA Astrophysics Data System (ADS)

    Jung, Sebin; Meng, Hong-Ying; Qin, Sheng-Feng

    2017-09-01

    As the overall population ages, driving-related accidents and injuries, associated with elderly drivers, have risen. Existing research about elderly drivers mainly focuses on factual data collection and analysis, indicating the elderly's growing fatal accident rates and their different behaviours compared to younger drivers. However, few research has focused on design-led practical solutions to mitigate the elderly's growing fatal accidents, by considering their usability and body conditions, afflicting the elderly, such as decreased vision, hearing, and reaction times. In this paper, first, current worldwide situations on growing fatal accident rates for elderly drivers is reviewed and the key impact factors are identified and discussed with regarding to usability and design trend in the automotive technology for elderly. Second, existing smart vehicle technology-based solutions to promote safe driving are explored and their pros and cons are discussed and analysed. Most of solutions are not created by people with driving difficulties, which are caused by health problems most commonly afflicting the elderly. Thirdly, diverse design-led research activities are taken, such as a survey, observation, and interviews to gain new understanding of what kinds of driving problems elderly drivers have and demonstrate how new system concepts could be developed for the elderly's benefits. Finally, it is found that the elderly's low vision and late reaction are main factors causing their driving difficulties. Based on this finding, usable vehicle system design ideas have been proposed, by utilising facial expression sensing technology as a solution. The proposed solutions would ensure reducing both the elderly's driving problems and high fatal accident rates and provide a more enjoyable driving environment for the elderly population.

  8. Key Drivers of Marines Willingness to Adopt Energy-Efficient Technologies

    DTIC Science & Technology

    2013-12-01

    influences the rate of adoption. Communication is “the process by which participants create and share information with one another in order to reach a...more likely to assess the value of the innovation themselves rather than the value of the implementer’s market . Kleijnen, Lee, and Wetzels (2009...willingness to ucc (~pt energy cftid(’nt technologil~. The adaptation of energy efficient technologies will significantly reduce fossil fuel der>endency

  9. Key Performance Parameter Driven Technology Goals for Electric Machines and Power Systems

    NASA Technical Reports Server (NTRS)

    Bowman, Cheryl; Jansen, Ralph; Brown, Gerald; Duffy, Kirsten; Trudell, Jeffrey

    2015-01-01

    Transitioning aviation to low carbon propulsion is one of the crucial strategic research thrust and is a driver in the search for alternative propulsion system for advanced aircraft configurations. This work requires multidisciplinary skills coming from multiple entities. The feasibility of scaling up various electric drive system technologies to meet the requirements of a large commercial transport is discussed in terms of key parameters. Functional requirements are identified that impact the power system design. A breakeven analysis is presented to find the minimum allowable electric drive specific power and efficiency that can preserve the range, initial weight, operating empty weight, and payload weight of the base aircraft.

  10. Gaining Momentum, Losing Ground. Tapping America's Potential, Progress Report 2008

    ERIC Educational Resources Information Center

    Tapping America's Potential, 2008

    2008-01-01

    In July 2005, 15 of America's most prominent business organizations joined together to express their deep concern about the ability of the United States to sustain its scientific and technological leadership in a world where newly energized foreign competitors are investing in the capacity for innovation--the key driver of productivity and…

  11. Integrating Technologies into ''Authentic'' Assessment Design: An Affordances Approach

    ERIC Educational Resources Information Center

    Osborne, Richard; Dunne, Elisabeth; Farrand, Paul

    2013-01-01

    Current pressures in higher education around student employability are driving new initiatives for change. Assessment is also a topic of debate, as it is a key driver of student behaviour, yet often falls behind other metrics in national surveys. In addition, increasing focus on digital literacies is catalysing new appreciations of what emerging…

  12. The U.S. Market For Broadband Over Powerline, 3. edition

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    2007-07-15

    The report provides a study of the potential market for BPL technology in the U.S. including a look at the past, present, and future state of Broadband Over Powerline (BPL) in the U.S. The Scope of the report includes the following topics: a description of the history of powerline communications (PLC) and broadband over powerline (BPL) technology; an analysis of key drivers of BPL within the electric utility and internet access industries; an overview of BPL technology and architecture; a comparison of BPL with alternative broadband access methods; an analysis of technological, regulatory, and business barriers to BPL's success; identificationmore » of the key applications and markets for BPL; a description of business models for BPL; an analysis of key market trends in broadband internet access; a review of the market development of cable modem broadband access; profiles of major U.S. BPL market participants; and, profiles of major U.S. BPL projects.« less

  13. Systems Engineering Applied to the Development of a Wave Energy Farm.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Roberts, Jesse D.; Bull, Diana L.; Costello, Ronan Patrick

    A motivation for undertaking this stakeholder requirements analysis and Systems Engineering exercise is to document the requirements for successful wave energy farms to facilitate better design and better design assessments. A difficulty in wave energy technology development is the absence to date of a verifiable minimum viable product against which the merits of new products might be measured. A consequence of this absence is that technology development progress, technology value, and technology funding have largely been measured, associated with, and driven by technology readiness, measured in technology readiness levels (TRLs). Originating primarily from the space and defense industries, TRLs focusmore » on procedural implementation of technology developments of large and complex engineering projects, where cost is neither mission critical nor a key design driver. The key deficiency with the TRL approach in the context of wave energy conversion is that WEC technology development has been too focused on commercial readiness and not enough on the stakeholder requirements and particularly economic viability required for market entry.« less

  14. LNDriver: identifying driver genes by integrating mutation and expression data based on gene-gene interaction network.

    PubMed

    Wei, Pi-Jing; Zhang, Di; Xia, Junfeng; Zheng, Chun-Hou

    2016-12-23

    Cancer is a complex disease which is characterized by the accumulation of genetic alterations during the patient's lifetime. With the development of the next-generation sequencing technology, multiple omics data, such as cancer genomic, epigenomic and transcriptomic data etc., can be measured from each individual. Correspondingly, one of the key challenges is to pinpoint functional driver mutations or pathways, which contributes to tumorigenesis, from millions of functional neutral passenger mutations. In this paper, in order to identify driver genes effectively, we applied a generalized additive model to mutation profiles to filter genes with long length and constructed a new gene-gene interaction network. Then we integrated the mutation data and expression data into the gene-gene interaction network. Lastly, greedy algorithm was used to prioritize candidate driver genes from the integrated data. We named the proposed method Length-Net-Driver (LNDriver). Experiments on three TCGA datasets, i.e., head and neck squamous cell carcinoma, kidney renal clear cell carcinoma and thyroid carcinoma, demonstrated that the proposed method was effective. Also, it can identify not only frequently mutated drivers, but also rare candidate driver genes.

  15. Technology-design-manufacturing co-optimization for advanced mobile SoCs

    NASA Astrophysics Data System (ADS)

    Yang, Da; Gan, Chock; Chidambaram, P. R.; Nallapadi, Giri; Zhu, John; Song, S. C.; Xu, Jeff; Yeap, Geoffrey

    2014-03-01

    How to maintain the Moore's Law scaling beyond the 193 immersion resolution limit is the key question semiconductor industry needs to answer in the near future. Process complexity will undoubtfully increase for 14nm node and beyond, which brings both challenges and opportunities for technology development. A vertically integrated design-technologymanufacturing co-optimization flow is desired to better address the complicated issues new process changes bring. In recent years smart mobile wireless devices have been the fastest growing consumer electronics market. Advanced mobile devices such as smartphones are complex systems with the overriding objective of providing the best userexperience value by harnessing all the technology innovations. Most critical system drivers are better system performance/power efficiency, cost effectiveness, and smaller form factors, which, in turns, drive the need of system design and solution with More-than-Moore innovations. Mobile system-on-chips (SoCs) has become the leading driver for semiconductor technology definition and manufacturing. Here we highlight how the co-optimization strategy influenced architecture, device/circuit, process technology and package, in the face of growing process cost/complexity and variability as well as design rule restrictions.

  16. Power requirements for commercial communications spacecraft

    NASA Technical Reports Server (NTRS)

    Billerbeck, W. J.

    1985-01-01

    Historical data on commercial spacecraft power systems are presented and their power requirements to the growth of satellite communications channel usage are related. Some approaches for estimating future power requirements of this class of spacecraft through the year 2000 are proposed. The key technology drivers in satellite power systems are addressed. Several technological trends in such systems are described, focusing on the most useful areas for research and development of major subsystems, including solar arrays, energy storage, and power electronics equipment.

  17. A scenario elicitation methodology to identify the drivers of electricity infrastructure cost in South America

    NASA Astrophysics Data System (ADS)

    Moksnes, Nandi; Taliotis, Constantinos; Broad, Oliver; de Moura, Gustavo; Howells, Mark

    2017-04-01

    Developing a set of scenarios to assess a proposed policy or future development pathways requires a certain level of information, as well as establishing the socio-economic context. As the future is difficult to predict, great care in defining the selected scenarios is needed. Even so it can be difficult to assess if the selected scenario is covering the possible solution space. Instead, this paper's methodology develops a large set of scenarios (324) in OSeMOSYS using the SAMBA 2.0 (South America Model Base) model to assess long-term electricity supply scenarios and applies a scenario-discovery statistical data mining algorithm, Patient Rule Induction Method (PRIM). By creating a multidimensional space, regions related to high and low cost can be identified as well as their key driver. The six key drivers are defined a priori in three (high, medium, low) or two levers (high, low): 1) Demand projected from GDP, population, urbanization and transport, 2) Fossil fuel price, 3) Climate change impact on hydropower, 4) Renewable technology learning rate, 5) Discount rate, 6) CO2 emission targets.

  18. Technology development and innovation for the bottom of the economic pyramid

    NASA Astrophysics Data System (ADS)

    Gadgil, Ashok

    2015-04-01

    Directed development of new technologies to solve specific problems of the poor in the developing world is a daunting task. Developing countries can be a wasteland littered with failed technologies sent there with much goodwill and effort from the industrial countries. Drawing on my team's experience I summarize our answers to some key questions for the technology designer or developer: How might one go about it? What works and what doesn't? What lessons can one draw from an examination of select successes and failures? The key lessons from our experience are: (1) successful technology design and implementation can not be separated from each other - they are tightly intertwined, (2) social factors are as critical for a technology's success as factors based on engineering science, and (3) ignorance of political economy, behavioral economics, organizational behavior, institutional imperatives, cultural norms and social drivers can prove fatal flaws when a new technology leaves the laboratory and meets the real world.

  19. Acceptability and validity of older driver screening with the DrivingHealth Inventory.

    PubMed

    Edwards, Jerri D; Leonard, Kathleen M; Lunsman, Melissa; Dodson, Joan; Bradley, Stacy; Myers, Charlsie A; Hubble, Bridgette

    2008-05-01

    Research has indicated that technology can be effectively used to identify high-risk older drivers. However, adaptation of such technology has been limited. Researchers debate whether older drivers represent a safety problem as well as whether they should be screened for driving fitness. The present study examined how drivers feel regarding technological screening and mandatory state testing. The validity and acceptability of a new technological screening battery for identifying high-risk drivers, the DrivingHealth Inventory (DHI), was also evaluated. In a sample of 258 Alabama drivers aged 18-87, older drivers performed significantly worse than younger drivers on sensory, cognitive, and physical subtests of the DHI, and older drivers with a crash history performed worse than older drivers without crashes. Regardless of age, 90% of participants supported states requiring screening for older drivers' license renewal. The majority of the participants (72%) supported use of technological screening batteries such as the DHI as a driver screening tool. Considering the acceptability and potential efficacy of the DHI, it may be a useful tool in evaluating driving fitness among older adults.

  20. A Vision of You-Topia: Personalising Professional Development of Teaching in a Diverse Academic Workforce

    ERIC Educational Resources Information Center

    Thomas, Lisa; Harden-Thew, Kathryn; Delahunty, Janine; Dean, Bonnie Amelia

    2016-01-01

    The higher education (HE) sector in Australia is in a state of flux due to a range of social, political and economic factors. Increased competition, greater student diversity, tautening of industry exigencies, reduced funding, and rapid technological advances are key drivers of change in this environment. Within this period of transformation, HE…

  1. Building Professional Social Media Communications Skills: A STEM-Originated Course with University-Wide Student Appeal

    ERIC Educational Resources Information Center

    Baim, Susan A.

    2016-01-01

    Routine correspondence with the author's business technology students indicated the need for increased skill and professionalism in social media communications as a key driver of successful career development strategies. A new course designed to assist students in transitioning from typical, casual social media use to the more rigorous and…

  2. Definition of optical systems payloads

    NASA Technical Reports Server (NTRS)

    Downey, J. A., III

    1981-01-01

    The various phases in the formulation of a major NASA project include the inception of the project, planning of the concept, and the project definition. A baseline configuration is established during the planning stage, which serves as a basis for engineering trade studies. Basic technological problems should be recognized early, and a technological verification plan prepared before development of a project begins. A progressive series of iterations is required during the definition phase, illustrating the complex interdependence of existing subsystems. A systems error budget should be established to assess the overall systems performance, identify key performance drivers, and guide performance trades and iterations around these drivers, thus decreasing final systems requirements. Unnecessary interfaces should be avoided, and reasonable design and cost margins maintained. Certain aspects of the definition of the Advanced X-ray Astrophysics Facility are used as an example.

  3. Design and Qualification of a SmallSat Stepper Motor Driver, Flight Results On-Board the Yes2 Satellite

    NASA Astrophysics Data System (ADS)

    Graczyk, R.; Kruijff, M.; Spiliotopoulos, I.

    2008-08-01

    Drivers for stepper motors are a commonly required critical technology for small satellites. This paper highlights the stepper driver design, test, and mission performance for the second Young Engineers' Satellite (YES2). The unit integrates the required digital and power parts and was developed with generic low-cost satellite applications in mind. One of the key mechanisms in YES2 is a friction brake containing a stepper motor which is in turn controlled by a stepper driver. The friction brake was used to control the deployment speed such that the tether deployed according to a pre-described two-stage trajectory. The stepper driver was itself commanded by an on-board computer that used tether deployment data as input and provided the new required position of the brake as output. The stepper driver design was driven by the requirements of a low cost yet reliable redundant design, use of a micro-controller and software commonly known to students, very small dimension, good thermal behavior and capable of delivering high torque at high efficiency. The work followed as much as possible ESA's design standards and was qualified by electromagnetic compatibility, thermal vacuum and shaker tests. It was functionally tested in real-time ground tether deployments. Mission data shows the stepper driver performed well in flight.

  4. "The little squealer" or "the virtual guardian angel"? Young drivers' and their parents' perspective on using a driver monitoring technology and its implications for parent-young driver communication.

    PubMed

    Guttman, Nurit; Gesser-Edelsburg, Anat

    2011-02-01

    In-vehicle driving monitoring technologies have the potential to enable young drivers to learn from self-assessment. However, their use is largely dependent on parental involvement. A total of 79 interviews were conducted with young drivers and parents regarding this technology and its use. Most had the experience of having an in-vehicle data recorder installed in the vehicle driven by the young drivers. Parents and the young drivers expressed both appreciation as well as reservations about its potential as a means to enhance the driving safety of young drivers. A surprising finding was that some parents did not check the feedback and said they relied on the young driver to do so. Main concerns related to privacy, parent-young driver relationship, self-esteem and confidence, constructive use of the feedback data, and the limitations of the documentation that can be done by the technology. Providing parents and young drivers with a support system and tools to discuss and utilize the feedback are underscored. Challenges include addressing the invasion of young drivers' privacy and gender differences, and using the monitoring-capacity of the technology to enhance safe driving practices. Implications for programs to enhance communication and a dialogical approach between parents and young drivers are discussed. Copyright © 2010 Elsevier Ltd. All rights reserved.

  5. Sensitivity of projected long-term CO2 emissions across the Shared Socioeconomic Pathways

    NASA Astrophysics Data System (ADS)

    Marangoni, G.; Tavoni, M.; Bosetti, V.; Borgonovo, E.; Capros, P.; Fricko, O.; Gernaat, D. E. H. J.; Guivarch, C.; Havlik, P.; Huppmann, D.; Johnson, N.; Karkatsoulis, P.; Keppo, I.; Krey, V.; Ó Broin, E.; Price, J.; van Vuuren, D. P.

    2017-01-01

    Scenarios showing future greenhouse gas emissions are needed to estimate climate impacts and the mitigation efforts required for climate stabilization. Recently, the Shared Socioeconomic Pathways (SSPs) have been introduced to describe alternative social, economic and technical narratives, spanning a wide range of plausible futures in terms of challenges to mitigation and adaptation. Thus far the key drivers of the uncertainty in emissions projections have not been robustly disentangled. Here we assess the sensitivities of future CO2 emissions to key drivers characterizing the SSPs. We use six state-of-the-art integrated assessment models with different structural characteristics, and study the impact of five families of parameters, related to population, income, energy efficiency, fossil fuel availability, and low-carbon energy technology development. A recently developed sensitivity analysis algorithm allows us to parsimoniously compute both the direct and interaction effects of each of these drivers on cumulative emissions. The study reveals that the SSP assumptions about energy intensity and economic growth are the most important determinants of future CO2 emissions from energy combustion, both with and without a climate policy. Interaction terms between parameters are shown to be important determinants of the total sensitivities.

  6. Commercialization of Plasma-Assisted Technologies: The Indian Experience

    NASA Astrophysics Data System (ADS)

    John, P. I.

    The paper describes an initiative by the Institute for Plasma Research (IPR), India in establishing links with the Indian industry for developing and commercialising advanced plasma-based industrial technologies. This has culminated in the creation of a self-financing technology development, incubation, demonstration and delivery facility. A business plan for converting the knowledge base to commercially viable technologies conceived technology as a product and the industry as the market and addressed issues like resistance to new technologies, the key role of entrepreneur, thrust areas and the necessity of technology incubation and delivery. Success of this strategy is discussed in a few case studies. We conclude by identifying the cost, environmental, strategic and techno-economic aspects, which would be the prime drivers for plasma-assisted manufacturing technology in India.

  7. Driving, navigation, and vehicular technology: experiences of older drivers and their co-pilots.

    PubMed

    Vrkljan, Brenda H; Polgar, Janice Miller

    2007-12-01

    The objective of this article is to explore relationship between older drivers and their passengers (co-pilots) and potential implications of in-vehicle navigation technology on their driving safety. Semi-structured interviews were conducted with 44 healthy, community-dwelling older adults (aged 60-83) or 22 married couples. Males identified themselves as drivers and females identified themselves as passengers (i.e., co-pilot). Findings indicate that operating a motor vehicle in older adulthood is a shared activity between drivers and passengers. Older drivers and co-pilots reported their level of interaction depended on their familiarity with their route. Navigating unfamiliar areas, particularly large urban centers, was identified as the most challenging driving situation. Participants identified their level of collaboration would increase with the advent of in-vehicle navigation technology. Safety concerns related to the use of this technology, included distraction of both drivers and passengers. Differences amongst couples in their perceptions of using this technology were linked to their level of experience with using other forms of technology. Older drivers and passengers identified working closely together when operating a motor vehicle. Further investigation into the effects of in-vehicle navigation technology on the driving safety of older drivers and their co-pilots is warranted.

  8. Driver strategies for engaging in distracting tasks using in-vehicle technologies

    DOT National Transportation Integrated Search

    2008-03-01

    This project investigated the decision process involved in a drivers willingness to engage in various technology-related and non-technology tasks. Previous research focused on how well drivers are able to drive while engaged in potentially distrac...

  9. EMERGENCE OF "DRIVERS" FOR THE IMPLEMENTATION OF HEALTH TECHNOLOGY ASSESSMENT.

    PubMed

    Castro Jaramillo, Hector Eduardo; Moreno-Mattar, Ornella; Osorio-Cuevas, Diana

    2016-01-01

    Health technology assessment (HTA) examines the consequences of the application of health technologies and is aimed at better informing decision-makers. Over the past 30 years, different countries have implemented HTA organizations. Colombia established by law its own HTA agency (IETS) in 2011 which started operations in November 2012. The aim of this study was to assess the feasibility of conducting and using HTA to inform decision-making in this context. Through a qualitative approach, ten "drivers" emerged with the ability to help or hinder HTA development in this context: availability and quality of data, implementation strategy, cultural aspects, local capacity, financial support, policy/political support, globalization, stakeholder pressure, health system context, and usefulness perception. Semi-structured interviews were conducted with key HTA researchers, after following rigorous transcription, and thematic content analysis, those aspects that may be barriers or facilitator for HTA development and use in Colombia were identified. Although HTA has become a tool to inform decision-making around the world, its use may vary according to setting. Determining those aspects which may enable or interfere with HTA development and use in Colombia may be useful for other countries when considering the establishment of HTA systems. The conceptual transferability of concepts like "drivers" with caveats may be of interest for similar settings trying to incorporate HTA processes and institutions into systematic decision-making.

  10. Toyota drivers' experiences with Dynamic Radar Cruise Control, Pre-Collision System, and Lane-Keeping Assist.

    PubMed

    Eichelberger, Angela H; McCartt, Anne T

    2016-02-01

    Advanced crash avoidance and driver assistance technologies potentially can prevent or mitigate many crashes. Previous surveys with drivers have found favorable opinions for many advanced technologies; however, these surveys are not necessarily representative of all drivers or all systems. As the technologies spread throughout the vehicle fleet, it is important to continue studying driver acceptance and use of them. This study focused on 2010-2013 Toyota Sienna and Prius models that were equipped with adaptive cruise control, forward collision avoidance, and lane departure warning and prevention (Prius models only). Telephone interviews were conducted in summer 2013 with 183 owners of vehicles with these technologies. About 9 in 10 respondents wanted adaptive cruise control and forward collision avoidance on their next vehicle, and 71% wanted lane departure warning/prevention again. Males and females reported some differences in their experiences with the systems; for example, males were more likely to have turned on lane departure warning/prevention than females, and when using this system, males reported more frequent warnings than did females. Relative to older drivers, drivers age 40 and younger were more likely to have seen or heard a forward collision warning. Consistent with the results in previous surveys of owners of luxury vehicles, the present survey found that driver acceptance of the technologies was high, although less so for lane departure warning/prevention. Experiences with the Toyota systems differed by driver age and gender to a greater degree than in previous surveys, suggesting that the responses of drivers may begin to differ as crash avoidance technology becomes available on a wider variety of vehicles. Crash avoidance technologies potentially can prevent or mitigate many crashes, but their success depends in part on driver acceptance. These systems will be effective only to the extent that drivers use them. Copyright © 2015 Elsevier Ltd and National Safety Council. All rights reserved.

  11. Towards a Scalable Group Vehicle-based Security System

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Carter, Jason M

    2016-01-01

    In August 2014, the National Highway Traffic Safety Administration (NHTSA) proposed new rulemaking to require V2V communication in light vehicles. To establish trust in the basic safety messages (BSMs) that are exchanged by vehicles to improve driver safety, a vehicle public key infrastructure (VPKI) is required. We outline a system where a group or groups of vehicles manage and generate their own BSM signing keys and authenticating certificates -- a Vehicle-Based Security System (VBSS). Based on our preliminary examination, we assert the mechanisms exist to implement a VBSS that supports V2V communications; however, maintaining uniform trust throughout the system whilemore » protecting individual privacy does require reliance on nascent group signature technology which may require a significant amount of communication overhead for trust maintenance. To better evaluate the VBSS approach, we compare it to the proposed Security Credential Management System (SCMS) in four major areas including bootstrapping, pseudonym provisioning, BSM signing and authentication, and revocation. System scale, driver privacy, and the distribution and dynamics of participants make designing an effective VPKI an interesting and challenging problem; no clear-cut strategy exists to satisfy the security and privacy expectations in a highly efficient way. More work is needed in VPKI research, so the life-saving promise of V2V technology can be achieved.« less

  12. Development of high precision digital driver of acoustic-optical frequency shifter for ROG

    NASA Astrophysics Data System (ADS)

    Zhang, Rong; Kong, Mei; Xu, Yameng

    2016-10-01

    We develop a high precision digital driver of the acoustic-optical frequency shifter (AOFS) based on the parallel direct digital synthesizer (DDS) technology. We use an atomic clock as the phase-locked loop (PLL) reference clock, and the PLL is realized by a dual digital phase-locked loop. A DDS sampling clock up to 320 MHz with a frequency stability as low as 10-12 Hz is obtained. By constructing the RF signal measurement system, it is measured that the frequency output range of the AOFS-driver is 52-58 MHz, the center frequency of the band-pass filter is 55 MHz, the ripple in the band is less than 1 dB@3MHz, the single channel output power is up to 0.3 W, the frequency stability is 1 ppb (1 hour duration), and the frequency-shift precision is 0.1 Hz. The obtained frequency stability has two orders of improvement compared to that of the analog AOFS-drivers. For the designed binary frequency shift keying (2-FSK) and binary phase shift keying (2-PSK) modulation system, the demodulating frequency of the input TTL synchronous level signal is up to 10 kHz. The designed digital-bus coding/decoding system is compatible with many conventional digital bus protocols. It can interface with the ROG signal detecting software through the integrated drive electronics (IDE) and exchange data with the two DDS frequency-shift channels through the signal detecting software.

  13. Systems thinking for assistive technology: a commentary on the GREAT summit.

    PubMed

    MacLachlan, Malcolm; Scherer, Marcia J

    2018-07-01

    The area of assistive technology has a long history of technological ingenuity and innovation. In order to ensure that the benefits of assistive technology are equitably distributed across the population and life course, it is necessary to adopt a systemic approach to the area. We describe examples of systems thinking and non-systems thinking across 10 Ps. These Ps are People (or users, as the primary beneficiaries of assistive technology), Policy, Products, Personnel, Provision (as key strategic drivers at systems level); and Procurement, Place, Pace, Promotion and Partnership (as key situational factors for systems). Together these Ps should constitute a framework for an "open" system that can evolve and adapt, that empowers users, inter-connects key components and locates these in the reality of differing contexts. The adoption of a stronger systems thinking perspective within the assistive technology field should allow for more equitable, more resilient and more sustainable assistive technology across high, middle- and low-income contexts and countries. Implications for Rehabilitation The progress of assistive technology provison has been hampered by disconnected initiatives and activities and this needs to be corrected. Systems thinking is a way of thinking about the connections between things and how these are influenced by contextual and other factors. By encouraging the providers and users of assitive technology to think more systemically we can provide a more cohesive and resilient systems. The user experience is the central component of systems thinking in assistive technologies.

  14. Facilitating telemedicine project sustainability in medically underserved areas: a healthcare provider participant perspective.

    PubMed

    Paul, David L; McDaniel, Reuben R

    2016-04-26

    Very few telemedicine projects in medically underserved areas have been sustained over time. This research furthers understanding of telemedicine service sustainability by examining teleconsultation projects from the perspective of healthcare providers. Drivers influencing healthcare providers' continued participation in teleconsultation projects and how projects can be designed to effectively and efficiently address these drivers is examined. Case studies of fourteen teleconsultation projects that were part of two health sciences center (HSC) based telemedicine networks was utilized. Semi-structured interviews of 60 key informants (clinicians, administrators, and IT professionals) involved in teleconsultation projects were the primary data collection method. Two key drivers influenced providers' continued participation. First was severe time constraints. Second was remote site healthcare providers' (RSHCPs) sense of professional isolation. Two design steps to address these were identified. One involved implementing relatively simple technology and process solutions to make participation convenient. The more critical and difficult design step focused on designing teleconsultation projects for collaborative, active learning. This learning empowered participating RSHCPs by leveraging HSC specialists' expertise. In order to increase sustainability the fundamental purpose of teleconsultation projects needs to be re-conceptualized. Doing so requires HSC specialists and RSHCPs to assume new roles and highlights the importance of trust. By implementing these design steps, healthcare delivery in medically underserved areas can be positively impacted.

  15. Precision medicine in the age of big data: The present and future role of large-scale unbiased sequencing in drug discovery and development.

    PubMed

    Vicini, P; Fields, O; Lai, E; Litwack, E D; Martin, A-M; Morgan, T M; Pacanowski, M A; Papaluca, M; Perez, O D; Ringel, M S; Robson, M; Sakul, H; Vockley, J; Zaks, T; Dolsten, M; Søgaard, M

    2016-02-01

    High throughput molecular and functional profiling of patients is a key driver of precision medicine. DNA and RNA characterization has been enabled at unprecedented cost and scale through rapid, disruptive progress in sequencing technology, but challenges persist in data management and interpretation. We analyze the state-of-the-art of large-scale unbiased sequencing in drug discovery and development, including technology, application, ethical, regulatory, policy and commercial considerations, and discuss issues of LUS implementation in clinical and regulatory practice. © 2015 American Society for Clinical Pharmacology and Therapeutics.

  16. 6 CFR 37.19 - Machine readable technology on the driver's license or identification card.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ..., States must use the ISO/IEC 15438:2006(E) Information Technology—Automatic identification and data... 6 Domestic Security 1 2011-01-01 2011-01-01 false Machine readable technology on the driver's..., Verification, and Card Issuance Requirements § 37.19 Machine readable technology on the driver's license or...

  17. 6 CFR 37.19 - Machine readable technology on the driver's license or identification card.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ..., States must use the ISO/IEC 15438:2006(E) Information Technology—Automatic identification and data... 6 Domestic Security 1 2010-01-01 2010-01-01 false Machine readable technology on the driver's..., Verification, and Card Issuance Requirements § 37.19 Machine readable technology on the driver's license or...

  18. The impact of new trends in POCTs for companion diagnostics, non-invasive testing and molecular diagnostics.

    PubMed

    Huckle, David

    2015-06-01

    Point-of-care diagnostics have been slowly developing over several decades and have taken on a new importance in current healthcare delivery for both diagnostics and development of new drugs. Molecular diagnostics have become a key driver of technology change and opened up new areas in companion diagnostics for use alongside pharmaceuticals and in new clinical approaches such as non-invasive testing. Future areas involving smartphone and other information technology advances, together with new developments in molecular biology, microfluidics and surface chemistry are adding to advances in the market. The focus for point-of-care tests with molecular diagnostic technologies is focused on advancing effective applications.

  19. Implications of advanced vehicle technologies for older drivers.

    PubMed

    Molnar, Lisa J; Eby, David W

    2017-09-01

    Advances are being made in vehicle technologies that may help older adults compensate for some of the declines in abilities associated with aging. These advances hold promise for increasing vehicle safety, reducing injuries, and making the driving task more comfortable. However, important research gaps remain with regard to how various advanced technologies impact the safety of older drivers, as well as older drivers' perceptions about these technologies. This special issue contains seven original contributions that address these issues. Specific topics include the: congruence of design guidelines with the needs and abilities of older drivers, transfer of control between automated and manual driving, use of in-vehicle monitoring technology, motivations for technology use and assigned meanings, technology valuation, and effects on driving behavior. Copyright © 2017 Elsevier Ltd. All rights reserved.

  20. Role of future scenarios in understanding deep uncertainty in ...

    EPA Pesticide Factsheets

    The environment and its interactions with human systems, whether economic, social or political, are complex. Relevant drivers may disrupt system dynamics in unforeseen ways, making it difficult to predict future conditions. This kind of deep uncertainty presents a challenge to organizations faced with making decisions about the future, including those involved in air quality management. Scenario Planning is a structured process that involves the development of narratives describing alternative future states of the world, designed to differ with respect to the most critical and uncertain drivers. The resulting scenarios are then used to understand the consequences of those futures and to prepare for them with robust management strategies. We demonstrate a novel air quality management application of Scenario Planning. Through a series of workshops, important air quality drivers were identified. The most critical and uncertain drivers were found to be “technological development” and “change in societal paradigms.” These drivers were used as a basis to develop four distinct scenario storylines. The energy and emission implications of each storyline were then modeled using the MARKAL energy system model. NOX and SO2 emissions were found to decrease for all scenarios, largely a response to existing air quality regulations. Future-year emissions differed considerably from one scenario to another, however, with key differentiating factors being transition

  1. The differential impact of low-carbon technologies on climate change mitigation cost under a range of socioeconomic and climate policy scenarios.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Barron, Robert W.; McJeon, Haewon C.

    2015-05-01

    This paper considers the effect of several key parameters of low carbon energy technologies on the cost of abatement. A methodology for determining the minimum level of performance required for a parameter to have a statistically significant impact on CO2 abatement cost is developed and used to evaluate the impact of eight key parameters of low carbon energy supply technologies on the cost of CO2 abatement. The capital cost of nuclear technology is found to have the greatest impact of the parameters studied. The cost of biomass and CCS technologies also have impacts, while their efficiencies have little, if any.more » Sensitivity analysis of the results with respect to population, GDP, and CO2 emission constraint show that the minimum performance level and impact of nuclear technologies is consistent across the socioeconomic scenarios studied, while the other technology parameters show different performance under higher population, lower GDP scenarios. Solar technology was found to have a small impact, and then only at very low costs. These results indicate that the cost of nuclear is the single most important driver of abatement cost, and that trading efficiency for cost may make biomass and CCS technologies more competitive.« less

  2. Reducing young driver road trauma: guidance and optimism for the future

    PubMed Central

    Senserrick, T M

    2006-01-01

    This paper highlights lessons from each of the Expert Panel papers in the present supplement that provide guidance for future research and initiatives. Although some shortfalls still remain in our understanding, it is argued that much has been learned and we are ready for more translation, implementation, and evaluation of multilevel interventions to help reduce young driver road trauma. Non‐use of restraints, speeding, driving at night and with passengers, and fatigue are highlighted as key risk factors to address. “Best practice” intervention is proposed as implementing and strengthening graduated driver licensing systems and complementary candidate programs and research, such as hazard perception training programs. A schematic cognitive‐perceptual model to explain the crash sequence process is explored. There is optimism that meaningful impacts can be made, especially coupled with the advances in vehicle technologies, but caution is necessary in the absence of targeted “real world” evaluations and broader implementation and diffusion strategies. PMID:16788114

  3. The “voice” has it: screen reader adoption and switching behavior among vision impaired persons in India

    PubMed Central

    Pal, Joyojeet; Cutrell, Edward

    2013-01-01

    We present results from a mixed methods study of screen reader use and switching behavior among people with vision impairments in India. We examine loyalty and experimentation with screen readers and find that the main drivers of adoption for early users differ significantly from the factors that drive continued use by advanced users. We discuss the factor that emerges as one of the strongest stated drivers of early adoption, TTS “voice” quality, particularly a “human-sounding voice” as one of the key features differentiating free/open source (FOSS) products from more expensive proprietary products. While the initial preferences are driven by voice quality, application support becomes more important over time as users speed up their sound settings and become more comfortable with the resultant non-human-sounding speech. We discuss these findings from two theoretical perspectives – first, through the application of the economics of behavior switching, and second, vis-à-vis novice and expert approaches toward new product adoption. We argue that these findings further our understanding of initial user comfort related to assistive technology adoption, and the impact of early technology choices on long-term technology switching behavior. PMID:24620705

  4. Harsh environment sensor development for advanced energy systems

    NASA Astrophysics Data System (ADS)

    Romanosky, Robert R.; Maley, Susan M.

    2013-05-01

    Highly efficient, low emission power systems have extreme conditions of high temperature, high pressure, and corrosivity that require monitoring. Sensing in these harsh environments can provide key information that directly impacts process control and system reliability. To achieve the goals and demands of clean energy, the conditions under which fossil fuels are converted into heat and power are harsh compared to traditional combustion/steam cycles. Temperatures can extend as high as 1600 Celsius (°C) in certain systems and pressures can reach as high as 5000 pounds per square inch (psi)/340 atmospheres (atm). The lack of suitable measurement technology serves as a driver for the innovations in harsh environment sensor development. Two major considerations in the development of harsh environments sensors are the materials used for sensing and the design of the sensing device. This paper will highlight the U.S. Department of Energy's, Office of Fossil Energy and National Energy Technology Laboratory's Program in advanced sensing concepts that are aimed at addressing the technology needs and drivers through the development of new sensor materials and designs capable of withstanding harsh environment conditions. Recent developments with harsh environment sensors will be highlighted and future directions towards in advanced sensing will be introduced.

  5. Driver acceptance of collision warning applications based on heavy-truck V2V technology

    DOT National Transportation Integrated Search

    2016-10-01

    Battelle conducted a series of driver acceptance clinics (DACs) with heavy-truck drivers to gauge their acceptance of collision-warning applications using vehicle-to-vehicle (V2V) communication technology. This report describes the results from Volpe...

  6. Reductions in self-reported stress and anticipatory heart rate with the use of a semi-automated parallel parking system.

    PubMed

    Reimer, Bryan; Mehler, Bruce; Coughlin, Joseph F

    2016-01-01

    Drivers' reactions to a semi-autonomous technology for assisted parallel parking system were evaluated in a field experiment. A sample of 42 drivers balanced by gender and across three age groups (20-29, 40-49, 60-69) were given a comprehensive briefing, saw the technology demonstrated, practiced parallel parking 3 times each with and without the assistive technology, and then were assessed on an additional 3 parking events each with and without the technology. Anticipatory stress, as measured by heart rate, was significantly lower when drivers approached a parking space knowing that they would be using the assistive technology as opposed to manually parking. Self-reported stress levels following assisted parks were also lower. Thus, both subjective and objective data support the position that the assistive technology reduced stress levels in drivers who were given detailed training. It was observed that drivers decreased their use of turn signals when using the semi-autonomous technology, raising a caution concerning unintended lapses in safe driving behaviors that may occur when assistive technologies are used. Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.

  7. 2015 Bioenergy Market Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Warner, Ethan; Moriarty, Kristi; Lewis, John

    This report is an update to the 2013 report and provides a status of the markets and technology development involved in growing a domestic bioenergy economy as it existed at the end of 2015. It compiles and integrates information to provide a snapshot of the current state and historical trends influencing the development of bioenergy markets. This version features details on the two major bioenergy markets: biofuels and biopower and an overview of bioproducts that enable bioenergy production. The information is intended for policy-makers as well as technology developers and investors tracking bioenergy developments. It also highlights some of themore » key energy and regulatory drivers of bioenergy markets.« less

  8. Impact of PON deployment on metro networks

    NASA Astrophysics Data System (ADS)

    Poirrier, Julien; Herviou, Fabrice; Barboule, Hélène; Moignard, Maryse

    2009-01-01

    FTTH or FTTC, depending on countries and areas, will be the key technology for operators to differentiate themselves from competitors and win market share. Such a disruptive evolution of the access network should be supported by a significant re-design of the higher network layers. In the present paper, the required features of these new WDM networks are presented. Capacity and cost are the two obvious drivers. But versatility will be crucial to cope with an uncertain context (tedious prediction of traffic, regulation and services) and with very diverse population densities. Finally we also address how PON could benefit from mature WDM technologies to ease the global network design.

  9. Prevalence, attitudes, and knowledge of in-vehicle technologies and vehicle adaptations among older drivers.

    PubMed

    Eby, David W; Molnar, Lisa J; Zakrajsek, Jennifer S; Ryan, Lindsay H; Zanier, Nicole; Louis, Renée M St; Stanciu, Sergiu C; LeBlanc, David; Kostyniuk, Lidia P; Smith, Jacqui; Yung, Raymond; Nyquist, Linda; DiGuiseppi, Carolyn; Li, Guohua; Mielenz, Thelma J; Strogatz, David

    2018-04-01

    The purpose of the present study was to gain a better understanding of the types of in-vehicle technologies being used by older drivers as well as older drivers' use, learning, and perceptions of safety related to these technologies among a large cohort of older drivers at multiple sites in the United States. A secondary purpose was to explore the prevalence of aftermarket vehicle adaptations and how older adults go about making adaptations and how they learn to use them. The study utilized baseline questionnaire data from 2990 participants from the Longitudinal Research on Aging Drivers (LongROAD) study. Fifteen in-vehicle technologies and 12 aftermarket vehicle adaptations were investigated. Overall, 57.2% of participants had at least one advanced technology in their primary vehicle. The number of technologies in a vehicle was significantly related to being male, having a higher income, and having a higher education level. The majority of respondents learned to use these technologies on their own, with "figured-it-out-myself" being reported by 25%-75% of respondents across the technologies. Overall, technologies were always used about 43% of the time, with wide variability among the technologies. Across all technologies, nearly 70% of respondents who had these technologies believed that they made them a safer driver. With regard to vehicle adaptations, less than 9% of respondents had at least one vehicle adaptation present, with the number of adaptations per vehicle ranging from 0 to 4. A large majority did not work with a professional to make or learn about the aftermarket vehicle adaptation. Copyright © 2018 Elsevier Ltd. All rights reserved.

  10. Flip chip bumping technology—Status and update

    NASA Astrophysics Data System (ADS)

    Juergen Wolf, M.; Engelmann, Gunter; Dietrich, Lothar; Reichl, Herbert

    2006-09-01

    Flip chip technology is a key driver for new complex system architectures and high-density packaging, e.g. sensor or pixel devices. Bumped wafers/dice as key elements become very important in terms of general availability at low cost, high yield and quality level. Today, different materials, e.g. Au, Ni, AuSn, SnAg, SnAgCu, SnCu, etc., are used for flip chip interconnects and different bumping approaches are available. Electroplating is the technology of choice for high-yield wafer bumping for small bump sizes and pitches. Lead-free solder bumps require an increase in knowledge in the field of under bump metallization (UBM) and the interaction of bump and substrate metallization, the formation and growth of intermetallic compounds (IMCs) during liquid- and solid-phase reactions. Results of a new bi-layer UBM of Ni-Cu which is especially designed for small-sized lead-free solder bumps will be discussed.

  11. Advanced driver assistance systems for teen drivers: Teen and parent impressions, perceived need, and intervention preferences.

    PubMed

    Weiss, Eve; Fisher Thiel, Megan; Sultana, Nahida; Hannan, Chloe; Seacrist, Thomas

    2018-02-28

    From the advent of airbags to electronic stability control, technological advances introduced into automobile design have significantly reduced injury and death from motor vehicle crashes. These advances are especially pertinent among teen drivers, a population whose leading cause of death is motor vehicle crashes. Recently developed advanced driver assistance systems (ADAS) have the potential to compensate for skill deficits and reduce overall crash risk. Yet, ADAS is only effective if drivers are willing to use it. Limited research has been conducted on the suitability of ADAS for teen drivers. The goal of this study is to identify teen drivers' perceived need for ADAS, receptiveness to in-vehicle technology, and intervention preferences. The long-term goal is to understand public perceptions and barriers to ADAS use and to help determine how these systems must evolve to meet the needs of the riskiest driving populations. Three focus groups (N = 24) were conducted with licensed teen drivers aged 16-19 years and 2 focus groups with parents of teen drivers (N = 12). Discussion topics included views on how ADAS might influence driving skills and behaviors; trust in technology; and data privacy. Discussions were transcribed; the team used conventional content analysis and open coding methods to identify 12 coding domains and code transcripts with NVivo 10. Interrater reliability testing showed moderate to high kappa scores. Overall, participants recognized potential benefits of ADAS, including improved safety and crash reduction. Teens suggested that ADAS is still developing and therefore has potential to malfunction. Many teens reported a greater trust in their own driving ability over vehicle technology. They expressed that novice drivers should learn to drive on non-ADAS-equipped cars and that ADAS should be considered a supplemental aid. Many teens felt that overreliance on ADAS may increase distracted driving or risky behaviors among teens. Parents also expressed skepticism for the technology but felt that it would likely be a useful support for teen drivers after the initial learning phase. This study elicited important end-user viewpoints by exploring the intersection between advanced automobile safety technology and human perception for the particular use case of teen drivers. For example, despite evidence that teens are the highest risk driving population, teens trust their own driving skills and competence more than in-vehicle technology. This understanding will ultimately advance the safety of teen drivers by identifying barriers to effective ADAS use.

  12. Experiences of model year 2011 Dodge and Jeep owners with collision avoidance and related technologies.

    PubMed

    Cicchino, Jessica B; McCartt, Anne T

    2015-01-01

    Crash avoidance technologies have the potential to prevent or mitigate many crashes, but their effectiveness depends on drivers' acceptance and proper use. Owners of 2011 Dodge Charger, Dodge Durango, and Jeep Grand Cherokee vehicles were interviewed about their experiences with their vehicles' technologies. Interviews were conducted in April 2013 with 215 owners of Dodge and Jeep vehicles with adaptive cruise control and forward collision warning and 215 owners with blind spot monitoring and rear cross-path detection. Most owners said that they always keep each collision avoidance technology turned on, and more than 90% of owners with each system would want the technology again on their next vehicle. The majority believed that the systems had helped prevent a collision; this ranged from 54% of drivers with forward collision warning to more than three-quarters with blind spot monitoring and rear cross-path detection. Some owners reported behavioral changes with the systems, but over-reliance on them is not prevalent. Reported use of the systems varied by the age and gender of the driver and duration of vehicle ownership to a greater degree than in previous surveys of luxury Volvo and Infiniti vehicles with collision avoidance technologies. Notably, drivers aged 40 and younger were most likely to report that forward collision warning had alerted them multiple times and that it had prevented a collision and that they follow the vehicle ahead less closely with adaptive cruise control. Reports of waiting for the alert from forward collision warning before braking were infrequent but increased with duration of ownership. However, these reports could reflect confusion of the system with adaptive cruise control, which alerts drivers when braking is necessary to maintain a preset speed or following distance but a crash is not imminent. Consistent with previous surveys of luxury vehicle owners with collision avoidance technologies, acceptance and use remains high among owners of more mainstream vehicles. Varying experiences with the technologies by driver age and gender suggest that safety benefits are not uniform for all drivers, and differential benefits may become increasingly apparent as collision avoidance technologies become available to a more heterogeneous population of drivers. The potential for over-reliance on the technologies should continue to be monitored, especially as drivers gain more experience with them.

  13. What technologies do people engage with while driving and why?

    PubMed

    Parnell, Katie J; Stanton, Neville A; Plant, Katherine L

    2018-02-01

    This paper presents the findings of a semi-structured interview study that was conducted to identify drivers' self-reported likelihood of engaging with technologies that are now commonly found in modern automobiles. Previous research has focused on the effect these technological tasks have on driving performance, but there has been less focus on how, why and when drivers choose to engage with them. As distraction remains a significant contributor to road accidents, an understanding of why it occurs will give important insights into how it can be prevented. A semi-structured interview schedule was developed to allow drivers to discuss the factors that influence their decision to engage with a variety of different technologies. The methodology facilitated both quantitative ratings of the drivers' likelihood of engaging in a variety of tasks and qualitative insights into why. Age and gender had some influence on the propensity to engage, in line with other findings in the literature, as did road type and task type. The reasons drivers gave for why they engage with potentially distracting tasks inform recommendations for preventing distraction related accidents from the increasingly prevalent sources of technologies available to drivers. Copyright © 2017 Elsevier Ltd. All rights reserved.

  14. Driving with advanced vehicle technology: A qualitative investigation of older drivers' perceptions and motivations for use.

    PubMed

    Gish, Jessica; Vrkljan, Brenda; Grenier, Amanda; Van Miltenburg, Benita

    2017-09-01

    For older drivers, in-vehicle technology offers much potential to improve safety and increase longevity of retaining both licensure and community mobility. However, little is known about how older drivers perceive Advanced Vehicle Technologies (AVTs) based on everyday driving experience. Interviews with 35 older drivers (20 men; 15 women) aged 60-85 who owned a vehicle with at least two AVTs (e.g., back-up camera, lane departure warning) were conducted to explore the meanings that older drivers assigned to AVTs and motivations for use, including whether age-related functional changes were part of their automobile purchase decision. Findings indicate that age-related changes are not a primary reason for why older adults seek out AVTs, but they still perceived and experienced AVTs to counteract age-related changes in driving performance based upon changes they felt occurring within the body. Older drivers also described AVTs as generating a sense of comfort behind-the-wheel. Comfort with this technology was equated with convenience, ease of use, and increased feelings of safety. Discussion emphasizes how assessments of the quality of driving performance and value of technology occur in relation to an aging body. Copyright © 2016 Elsevier Ltd. All rights reserved.

  15. Behind the wheel: community consultation informs adaptation of safe-transport program for older drivers.

    PubMed

    Coxon, Kristy; Keay, Lisa

    2015-12-09

    Safe-transport is important to well-being in later life but balancing safety and independence for older drivers can be challenging. While self-regulation is a promising tool to promote road safety, more research is required to optimise programs. Qualitative research was used to inform the choice and adaptation of a safe-transport education program for older drivers. Three focus groups were conducted with older drivers living in northwest Sydney to explore four key areas related to driving in later life including aged-based licensing, stopping or limiting driving, barriers to driving cessation and alternative modes of transportation. Data were analysed using content analysis. Four categories emerged from the data; bad press for older drivers, COMPETENCE not age, call for fairness in licensing regulations, and hanging up the keys: It's complicated! Two key issues being (1) older drivers wanted to drive for as long as possible but (2) were not prepared for driving cessation; guided the choice and adaption of the Knowledge Enhances Your Safety (KEYS) program. This program was adapted for the Australian context and focus group findings raised the need for practical solutions, including transport alternatives, to be added. Targeted messages were developed from the data using the Precaution Adoption Process Model (PAPM), allowing the education to be tailored to the individual's stage of behaviour change. Adapting our program based on insights gained from community consultation should ensure the program is sensitive to the needs, skills and preferences of older drivers.

  16. Problems, policies and politics: making the case for better assistive technology provision in Australia.

    PubMed

    Layton, Natasha

    2015-05-01

    Substantial evidence supports assistive technology and environmental adaptations as key enablers to participation. In order to realise the potential of these interventions, they need to be both recognised in policy, and resourced in practice. This paper uses political theory to understand the complexities of assistive technology (AT) policy reform in Australia. AT research will not be influential in improving AT policy without consideration of political drivers. Theories of policy formation are considered, with Kingdon's (2003) theory of multiple streams identified as a useful lens through which to understand government actions. This theory is applied to the case of current AT policy reformulation in Australia. The convergence model of problem identification, policy formulation and political will is found to be an applicable construct with which to evaluate contemporary policy changes. This paper illustrates the cogency of this theory for the field of AT, in the case of Australia's recent disability and aged care reforms. Political theory provides a way of conceptualising the difficulties of consumers and AT practitioners experience in getting therapeutically valid solutions into public policy, and then getting policies prioritised and funded. It is suggested that AT practitioners must comprehend and consider political factors in working towards effective policies to support their practice. AT practitioners generally lack political awareness or an understanding of the drivers of policy. The effectiveness of AT practitioners at a systemic level will remain limited without consideration of policy drivers. AT practitioners must comprehend and consider political factors in working towards effective policies to support their practice.

  17. The use of technology to address patterns of risk among teenage drivers.

    PubMed

    Brovold, Shawn; Ward, Nic; Donath, Max; Simon, Stephen; Shankwitz, Craig; Creaser, Janet

    2007-01-01

    The crash risk of teens is high, with fatal crash rates of teen drivers higher than any other age group. New approaches to reduce teen traffic fatalities are clearly needed. A possible approach to reduce the incidence of teen driver crashes and fatalities is through the use of vehicle-based intelligent driver support systems. To be most effective, the system should address the behaviors associated with an overwhelming number of teen fatal crashes: speed, low seatbelt use, and alcohol impairment. In-vehicle technology also offers an opportunity to address the issue of inexperience through enforcement of certain Graduated Driver's License provisions. To fully understand the capability of such technologies, there should be a concerted effort to further their development, and human factors testing should take place to understand their effects on the driver. If successfully implemented, a Teen Driver Support System (TDSS), such as the one described here, could significantly decrease the number of teens killed in traffic crashes.

  18. Vision and commercial motor vehicle driver safety : vol. 2 : appendix G

    DOT National Transportation Integrated Search

    2007-12-14

    The purpose of this evidence report is to address several key questions posed by the Federal Motor Carrier Safety Administration (FMCSA) that pertain to vision and commercial motor vehicle (CMV) driver safety. Each of these key questions was develope...

  19. Vision and commercial motor vehicle driver safety : vol. 1 : evidence report

    DOT National Transportation Integrated Search

    2008-06-06

    The purpose of this evidence report is to address several key questions posed by the Federal Motor Carrier Safety Administration (FMCSA) that pertain to vision and commercial motor vehicle (CMV) driver safety. Each of these key questions was develope...

  20. Access from Space: A New Perspective on NASA's Space Transportation Technology Requirements and Opportunities

    NASA Technical Reports Server (NTRS)

    Rasky, Daniel J.

    2004-01-01

    The need for robust and reliable access from space is clearly demonstrated by the recent loss of the Space Shuttle Columbia; as well as the NASA s goals to get the Shuttle re-flying and extend its life, build new vehicles for space access, produce successful robotic landers and s a q k retrr? llisrions, and maximize the science content of ambitious outer planets missions that contain nuclear reactors which must be safe for re-entry after possible launch aborts. The technology lynch pin of access from space is hypersonic entry systems such the thermal protection system, along with navigation, guidance and control (NG&C). But it also extends to descent and landing systems such as parachutes, airbags and their control systems. Current space access technology maturation programs such as NASA s Next Generation Launch Technology (NGLT) program or the In-Space Propulsion (ISP) program focus on maturing laboratory demonstrated technologies for potential adoption by specific mission applications. A key requirement for these programs success is a suitable queue of innovative technologies and advanced concepts to mature, including mission concepts enabled by innovative, cross cutting technology advancements. When considering space access, propulsion often dominates the capability requirements, as well as the attention and resources. From the perspective of access from space some new cross cutting technology drivers come into view, along with some new capability opportunities. These include new miniature vehicles (micro, nano, and picosats), advanced automated systems (providing autonomous on-orbit inspection or landing site selection), and transformable aeroshells (to maximize capabilities and minimize weight). This paper provides an assessment of the technology drivers needed to meet future access from space mission requirements, along with the mission capabilities that can be envisioned from innovative, cross cutting access from space technology developments.

  1. Assessing the utility of TAM, TPB, and UTAUT for advanced driver assistance systems.

    PubMed

    Rahman, Md Mahmudur; Lesch, Mary F; Horrey, William J; Strawderman, Lesley

    2017-11-01

    Advanced Driver Assistance Systems (ADAS) are intended to enhance driver performance and improve transportation safety. The potential benefits of these technologies, such as reduction in number of crashes, enhancing driver comfort or convenience, decreasing environmental impact, etc., have been acknowledged by transportation safety researchers and federal transportation agencies. Although these systems afford safety advantages, they may also challenge the traditional role of drivers in operating vehicles. Driver acceptance, therefore, is essential for the implementation of these systems into the transportation system. Recognizing the need for research into the factors affecting driver acceptance, this study assessed the utility of the Technology Acceptance Model (TAM), the Theory of Planned Behavior (TPB), and the Unified Theory of Acceptance and Use of Technology (UTAUT) for modelling driver acceptance in terms of Behavioral Intention to use an ADAS. Each of these models propose a set of factors that influence acceptance of a technology. Data collection was done using two approaches: a driving simulator approach and an online survey approach. In both approaches, participants interacted with either a fatigue monitoring system or an adaptive cruise control system combined with a lane-keeping system. Based on their experience, participants responded to several survey questions to indicate their attitude toward using the ADAS and their perception of its usefulness, usability, etc. A sample of 430 surveys were collected for this study. Results found that all the models (TAM, TPB, and UTAUT) can explain driver acceptance with their proposed sets of factors, each explaining 71% or more of the variability in Behavioral Intention. Among the models, TAM was found to perform the best in modelling driver acceptance followed by TPB. The findings of this study confirm that these models can be applied to ADAS technologies and that they provide a basis for understanding driver acceptance. Copyright © 2017 Elsevier Ltd. All rights reserved.

  2. Foresight Study on the Risk Governance of New Technologies: The Case of Nanotechnology.

    PubMed

    Read, Sheona A K; Kass, Gary S; Sutcliffe, Hilary R; Hankin, Steven M

    2016-05-01

    Technology-led innovation represents an important driver of European economic and industrial competitiveness and offers solutions to societal challenges. In order to facilitate responsible innovation and public acceptance, a need exists to identify and implement oversight approaches focused on the effective risk governance of emerging technologies. This article describes a foresight study on the governance of new technologies, using nanotechnology as a case example. Following a mapping of the governance landscape, four plausible foresight scenarios were developed, capturing critical uncertainties for nanotechnology governance. Key governance elements were then stress tested within these scenarios to see how well they might perform in a range of possible futures and to inform identification of the strengths, weaknesses, opportunities, and threats for nanotechnology governance in Europe. Based on the study outcomes, recommendations are proposed regarding the development of governance associated with the responsible development of new technologies. © 2015 Society for Risk Analysis.

  3. Waste Processing Research and Technology Development at NASA Ames Research Center

    NASA Technical Reports Server (NTRS)

    Fisher, John; Kliss, Mark

    2004-01-01

    The current "store and return" approach for handling waste products generated during low Earth orbit missions will not meet the requirements for future human missions identified in NASA s new Exploration vision. The objective is to develop appropriate reliable waste management systems that minimize maintenance and crew time, while maintaining crew health and safety, as well as providing protection of planetary surfaces. Solid waste management requirements for these missions include waste volume reduction, stabilization and storage, water recovery, and ultimately recovery of carbon dioxide, nutrients and other resources from a fully regenerative food production life support system. This paper identifies the key drivers for waste management technology development within NASA, and provides a roadmap for the developmental sequence and progression of technologies. Recent results of research and technology development activities at NASA Ames Research Center on candidate waste management technologies with emphasis on compaction, lyophilization, and incineration are discussed.

  4. Creativity as a Key Driver for Designing Context Sensitive Health Informatics.

    PubMed

    Zhou, Chunfang; Nøhr, Christian

    2017-01-01

    In order to face the increasing challenges of complexity and uncertainty in practice of health care, this paper aims to discuss how creativity can contribute to design new technologies in health informatics systems. It will firstly introduce the background highlighting creativity as a missing element in recent studies on context sensitive health informatics. Secondly, the concept of creativity and its relationship with activities of technology design will be discussed from a socio-culture perspective. This will be thirdly followed by understanding the roles of creativity in designing new health informatics technologies for meeting needs of high context sensitivity. Finally, a series of potential strategies will be suggested to improve creativity among technology designers working in healthcare industries. Briefly, this paper innovatively bridges two areas studies on creativity and context sensitive health informatics by issues of technology design that also indicates its important significances for future research.

  5. An introduction to medical simulation.

    PubMed

    Brindley, Peter G; Arabi, Yaseen M

    2009-08-01

    While medical simulation is no panacea, it offers numerous potential strategies for comprehensive and practical training, safer patient care, and for those keen to attract and retain staff. It is a technique, rather than just a technology that promotes experiential and reflective learning. It is also a key strategy to teach Crisis Resource Management skills. Simulation can benefit the individual learner, the multidisciplinary team, and the hospital as a whole. It has been described as a key driver of patient safety, and even as the patient safety laboratory of the future. As such is endorsed by many professional societies in many nations. While challenges remain (and are outlined) there are great opportunities for clinicians, administrators, and educators alike.

  6. Key beliefs influencing young drivers' engagement with social interactive technology on their smartphones: A qualitative study.

    PubMed

    Gauld, Cassandra S; Lewis, Ioni M; White, Katherine M; Watson, Barry

    2016-01-01

    The main aim of this study was to identify young drivers' underlying beliefs (i.e., behavioral, normative, and control) regarding initiating, monitoring/reading, and responding to social interactive technology (i.e., functions on a Smartphone that allow the user to communicate with other people). This qualitative study was a beliefs elicitation study in accordance with the theory of planned behavior and sought to elicit young drivers' behavioral (i.e., advantages, disadvantages), normative (i.e., who approves, who disapproves), and control beliefs (i.e., barriers, facilitators) that underpin social interactive technology use while driving. Young drivers (N = 26) aged 17 to 25 years took part in an interview or focus group discussion. Though differences emerged between the 3 behaviors of initiating, monitoring/reading, and responding for each of the behavioral, normative, and control belief categories, the strongest distinction was within the behavioral beliefs category (e.g., communicating with the person that they were on the way to meet was an advantage of initiating; being able to determine whether to respond was an advantage of monitoring/reading; and communicating with important people was an advantage of responding). Normative beliefs were similar for initiating and responding behaviors (e.g., friends and peers more likely to approve than other groups) and differences emerged for monitoring/reading (e.g., parents were more likely to approve of this behavior than initiating and responding). For control beliefs, there were differences between the beliefs regarding facilitators of these behaviors (e.g., familiar roads and conditions facilitated initiating; having audible notifications of an incoming communication facilitated monitoring/reading; and receiving a communication of immediate importance facilitated responding); however, the control beliefs that presented barriers were consistent across the 3 behaviors (e.g., difficult traffic/road conditions). The current study provides an important addition to the extant literature and supports emerging research that suggests that initiating, monitoring/reading, and responding may indeed be distinct behaviors with different underlying motivations.

  7. Recognition method of construction conflict based on driver's eye movement.

    PubMed

    Xu, Yi; Li, Shiwu; Gao, Song; Tan, Derong; Guo, Dong; Wang, Yuqiong

    2018-04-01

    Drivers eye movement data in simulated construction conflicts at different speeds were collected and analyzed to find the relationship between the drivers' eye movement and the construction conflict. On the basis of the relationship between the drivers' eye movement and the construction conflict, the peak point of wavelet processed pupil diameter, the first point on the left side of the peak point and the first blink point after the peak point are selected as key points for locating construction conflict periods. On the basis of the key points and the GSA, a construction conflict recognition method so called the CCFRM is proposed. And the construction conflict recognition speed and location accuracy of the CCFRM are verified. The good performance of the CCFRM verified the feasibility of proposed key points in construction conflict recognition. Copyright © 2018 Elsevier Ltd. All rights reserved.

  8. Driver Distraction Using Visual-Based Sensors and Algorithms.

    PubMed

    Fernández, Alberto; Usamentiaga, Rubén; Carús, Juan Luis; Casado, Rubén

    2016-10-28

    Driver distraction, defined as the diversion of attention away from activities critical for safe driving toward a competing activity, is increasingly recognized as a significant source of injuries and fatalities on the roadway. Additionally, the trend towards increasing the use of in-vehicle information systems is critical because they induce visual, biomechanical and cognitive distraction and may affect driving performance in qualitatively different ways. Non-intrusive methods are strongly preferred for monitoring distraction, and vision-based systems have appeared to be attractive for both drivers and researchers. Biomechanical, visual and cognitive distractions are the most commonly detected types in video-based algorithms. Many distraction detection systems only use a single visual cue and therefore, they may be easily disturbed when occlusion or illumination changes appear. Moreover, the combination of these visual cues is a key and challenging aspect in the development of robust distraction detection systems. These visual cues can be extracted mainly by using face monitoring systems but they should be completed with more visual cues (e.g., hands or body information) or even, distraction detection from specific actions (e.g., phone usage). Additionally, these algorithms should be included in an embedded device or system inside a car. This is not a trivial task and several requirements must be taken into account: reliability, real-time performance, low cost, small size, low power consumption, flexibility and short time-to-market. The key points for the development and implementation of sensors to carry out the detection of distraction will also be reviewed. This paper shows a review of the role of computer vision technology applied to the development of monitoring systems to detect distraction. Some key points considered as both future work and challenges ahead yet to be solved will also be addressed.

  9. Driver Distraction Using Visual-Based Sensors and Algorithms

    PubMed Central

    Fernández, Alberto; Usamentiaga, Rubén; Carús, Juan Luis; Casado, Rubén

    2016-01-01

    Driver distraction, defined as the diversion of attention away from activities critical for safe driving toward a competing activity, is increasingly recognized as a significant source of injuries and fatalities on the roadway. Additionally, the trend towards increasing the use of in-vehicle information systems is critical because they induce visual, biomechanical and cognitive distraction and may affect driving performance in qualitatively different ways. Non-intrusive methods are strongly preferred for monitoring distraction, and vision-based systems have appeared to be attractive for both drivers and researchers. Biomechanical, visual and cognitive distractions are the most commonly detected types in video-based algorithms. Many distraction detection systems only use a single visual cue and therefore, they may be easily disturbed when occlusion or illumination changes appear. Moreover, the combination of these visual cues is a key and challenging aspect in the development of robust distraction detection systems. These visual cues can be extracted mainly by using face monitoring systems but they should be completed with more visual cues (e.g., hands or body information) or even, distraction detection from specific actions (e.g., phone usage). Additionally, these algorithms should be included in an embedded device or system inside a car. This is not a trivial task and several requirements must be taken into account: reliability, real-time performance, low cost, small size, low power consumption, flexibility and short time-to-market. The key points for the development and implementation of sensors to carry out the detection of distraction will also be reviewed. This paper shows a review of the role of computer vision technology applied to the development of monitoring systems to detect distraction. Some key points considered as both future work and challenges ahead yet to be solved will also be addressed. PMID:27801822

  10. Driving Simulator Based Interactive Experiments : Understanding Driver Behavior, Cognition and Technology Uptake under Information and Communication Technologies

    DOT National Transportation Integrated Search

    2018-01-31

    Advanced Traveler Information Systems (ATIS) and in-vehicle information systems (IVIS) are becoming an integral part of the current driving experience. Although information through in-vehicle technologies provides assistance to drivers with diverse t...

  11. Spying or steering? Views of parents of young novice drivers on the use and ethics of driver-monitoring technologies.

    PubMed

    Guttman, Nurit; Lotan, Tsippy

    2011-01-01

    In-vehicle technologies that document driving practices have the potential to enhance the driving safety of young drivers, but their installation depends largely on their parents' willingness and raises ethical dilemmas. This study investigated, using closed and open-ended questions, the views of 906 parents of young drivers in Israel regarding their willingness to install such a technology, and their conceptions of social norms and ethical issues associated with the technology and of factors that would encourage or discourage parents to adopt it. Most believed parents should feel morally obligated to install it. When cost was not a consideration, most said they would, and believed other parents would be willing to install the technology. Fewer (about half) expressed willingness to install it after being told about its estimated cost. Monetary cost was rated as a barrier to install it by about half. Environmental considerations were viewed as an incentive. Parents who supported the installation believed it would serve as a trigger for parent-young driver communication but those who did not thought it would erode trust in the parent-young driver relationship. Most said parents should have access to the monitoring data. Policy implications regarding issues of privacy and resources for parents are discussed. Copyright © 2010 Elsevier Ltd. All rights reserved.

  12. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Miller, M.J.

    The author outlines what he considers to be the key environmental issues affecting Clean Coal Technology (CCT) deployment both in the US and internationally. Since the international issues are difficult to characterize given different environmental drivers in various countries and regions, the primary focus of his remarks is on US deployment. However, he makes some general remarks, particularly regarding the environmental issues in developing vs. developed countries and how these issues may affect CCT deployment. Further, how environment affects deployment depends on which particular type of clean coal technology one is addressing. It is not the author`s intention to mentionmore » many specific technologies other than to use them for the purposes of example. He generally categorizes CCTs into four groups since environment is likely to affect deployment for each category somewhat differently. These four categories are: Precombustion technologies such as coal cleaning; Combustion technologies such as low NOx burners; Postcombustion technologies such as FGD systems and postcombustion NOx control; and New generation technologies such as gasification and fluidized bed combustion.« less

  13. Selection of shuttle payload data processing drivers for the data system new technology study

    NASA Technical Reports Server (NTRS)

    1976-01-01

    An investigation of all payloads in the IBM disciplines and the selection of driver payloads within each discipline are described. The driver payloads were selected on the basis of their data processing requirements. These requirements are measured by a weighting scheme. The total requirements for each discipline are estimated by use of the technology payload model. The driver selection process which was both a payload by payload comparison and a comparison of expected groupings of payloads was examined.

  14. Evaluating driver reactions to new vehicle technologies intended to increase safety and mobility across the lifespan.

    DOT National Transportation Integrated Search

    2013-05-01

    Personal vehicle manufactures are introducing a wide range of new technologies that are : intended to increase the safety, comfort, and mobility of drivers of all ages. Examples range from : semi-autonomous technologies such as adaptive cruise contro...

  15. Traffic Operations Control For Older Drivers And Pedestrians: Summary Report

    DOT National Transportation Integrated Search

    1996-07-01

    The purpose of this investigation was to determine which intersection operational characteristics could be altered to accommodate age-related changes. Two key drivers issues were examined in order to identify the specific older driver problems and th...

  16. Key drivers of airline loyalty.

    PubMed

    Dolnicar, Sara; Grabler, Klaus; Grün, Bettina; Kulnig, Anna

    2011-10-01

    This study investigates drivers of airline loyalty. It contributes to the body of knowledge in the area by investigating loyalty for a number of a priori market segments identified by airline management and by using a method which accounts for the multi-step nature of the airline choice process. The study is based on responses from 687 passengers. Results indicate that, at aggregate level, frequent flyer membership, price, the status of being a national carrier and the reputation of the airline as perceived by friends are the variables which best discriminate between travellers loyal to the airline and those who are not. Differences in drivers of airline loyalty for a number of segments were identified. For example, loyalty programs play a key role for business travellers whereas airline loyalty of leisure travellers is difficult to trace back to single factors. For none of the calculated models satisfaction emerged as a key driver of airline loyalty.

  17. Key drivers of airline loyalty

    PubMed Central

    Dolnicar, Sara; Grabler, Klaus; Grün, Bettina; Kulnig, Anna

    2011-01-01

    This study investigates drivers of airline loyalty. It contributes to the body of knowledge in the area by investigating loyalty for a number of a priori market segments identified by airline management and by using a method which accounts for the multi-step nature of the airline choice process. The study is based on responses from 687 passengers. Results indicate that, at aggregate level, frequent flyer membership, price, the status of being a national carrier and the reputation of the airline as perceived by friends are the variables which best discriminate between travellers loyal to the airline and those who are not. Differences in drivers of airline loyalty for a number of segments were identified. For example, loyalty programs play a key role for business travellers whereas airline loyalty of leisure travellers is difficult to trace back to single factors. For none of the calculated models satisfaction emerged as a key driver of airline loyalty. PMID:27064618

  18. Evaluating public education messages aimed at monitoring and responding to social interactive technology on smartphones among young drivers.

    PubMed

    Gauld, Cassandra S; Lewis, Ioni; White, Katherine M; Fleiter, Judy J; Watson, Barry

    2017-07-01

    Young drivers are more likely than any other age group to access social interactive technology (e.g., Facebook, E-mail) on a smartphone while driving. The current study formed part of a larger investigation and was guided by The Step Approach to Message Design and Testing (SatMDT) to evaluate the relative effectiveness of three different public education messages aimed at reducing smartphone use among young drivers. The messages were each adapted to the specific behaviours of monitoring/reading and responding to social interactive technology on smartphones. Participants (n=288; 199F, 89M) were drivers aged 17-25 years who resided in the Australian state of Queensland. Message acceptance (i.e., intention and effectiveness) and message rejection were both assessed using a self-report survey. Multivariate analyses found that, overall, the messages targeting monitoring/reading behaviour were considered more effective than those targeting responding behaviour. The message that challenged the underlying motivation that believing you are a good driver makes it easier to monitor/read social interactive technology while driving was considered particularly effective by young male drivers. Copyright © 2017 Elsevier Ltd. All rights reserved.

  19. Creating the environment for driver distraction: A thematic framework of sociotechnical factors.

    PubMed

    Parnell, Katie J; Stanton, Neville A; Plant, Katherine L

    2018-04-01

    As modern society becomes more reliant on technology, its use within the vehicle is becoming a concern for road safety due to both portable and built-in devices offering sources of distraction. While the effects of distracting technologies are well documented, little is known about the causal factors that lead to the drivers' engagement with technological devices. The relevance of the sociotechnical system within which the behaviour occurs requires further research. This paper presents two experiments, the first aims to assess the drivers self-reported decision to engage with technological tasks while driving and their reasoning for doing so with respect to the wider sociotechnical system. This utilised a semi-structured interview method, conducted with 30 drivers to initiate a discussion on their likelihood of engaging with 22 different tasks across 7 different road types. Inductive thematic analysis provided a hierarchical thematic framework that detailed the self-reported causal factors that influence the drivers' use of technology whilst driving. The second experiment assessed the relevance of the hierarchical framework to a model of distraction that was established from within the literature on the drivers use of distracting technologies while driving. The findings provide validation for some relationships studied in the literature, as well as providing insights into relationships that require further study. The role of the sociotechnical system in the engagement of distractions while driving is highlighted, with the causal factors reported by drivers suggesting the importance of considering the wider system within which the behaviour is occurring and how it may be creating the conditions for distraction to occur. This supports previous claims made within the literature based model. Recommendations are proposed that encourage a movement away from individual focused countermeasures towards systemic actors. Copyright © 2017 Elsevier Ltd. All rights reserved.

  20. The role of anaerobic digestion in the emerging energy economy.

    PubMed

    Batstone, Damien John; Virdis, Bernardino

    2014-06-01

    Anaerobic digestion is the default process for biological conversion of residue organics to renewable energy and biofuel in the form of methane. However, its scope of application is expanding, due to availability of new technologies, and the emerging drivers of energy and nutrient conservation and recovery. Here, we outline two of these new application areas, namely wastewater nutrient and energy recovery, and generation of value added chemicals through mixed culture biotechnology. There exist two options for nutrient and energy recovery from domestic wastewater: low energy mainline and partition-release-recovery. Both are heavily dependent on anaerobic digestion as an energy generating and nutrient release step, and have been enabled by new technologies such as low emission anaerobic membrane processes. The area of mixed culture biotechnology has been previously identified as a key industrial opportunity, but is now moving closer to application due application of existing and new technologies. As well as acting as a core technology option in bioproduction, anaerobic digestion has a key role in residual waste valorization and generation of energy for downstream processing. These new application areas and technologies are emerging simultaneously with substantial advances in knowledge of underlying mechanisms such as electron transfer, understanding of which is critical to development of the new application areas. Copyright © 2014 Elsevier Ltd. All rights reserved.

  1. Human Factors Design Of Automated Highway Systems: Scenario Definition

    DOT National Transportation Integrated Search

    1995-09-01

    Attention to driver acceptance and performance issues during system design will be key to the success of the Automated Highway System (AHS). A first step in the process of defining driver roles and driver-system interface requirements of AHS is the d...

  2. Teaching Driver Education Technology to Novice Drivers.

    ERIC Educational Resources Information Center

    Young, Anthony

    A cybernetic unit in driver education was developed to help grade 10 students develop the skills needed to acquire and process driver education information and prepare for the driving phase of driver education in grade 11. Students used a simulator to engage in a series of scenarios designed to promote development of social, behavioral, and mental…

  3. Role of home automation in distribution automation and automated meter reading. Tropical report, December 1994

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Davis, K.W.

    1994-12-01

    This is one of a series of topical reports dealing with the strategic, technical, and market development of home automation. Particular emphasis is placed upon identifying those aspects of home automation that will impact the gas industry and gas products. Communication standards, market drivers, key organizations, technical implementation, product opportunities, and market growth projects will all be addressed in this or subsequent reports. These reports will also discuss how the gas industry and gas-fired equipment can use home automation technology to benefit the consumer.

  4. What's the law got to do with it? Legislation regarding in-vehicle technology use and its impact on driver distraction.

    PubMed

    Parnell, Katie J; Stanton, Neville A; Plant, Katherine L

    2017-03-01

    Legislation in the road transport domain aims to control safety on the roads. Despite this, a critical issue affecting road safety is that of driver distraction. Although poorly defined, distraction is a significant road safety issue which, in part, is caused by the prevalence of technology within vehicles. Legislation surrounding the use of in-vehicle technologies are explored in this paper from a socio-technical system perspective. This reveals the wider context of the road transport system operating under the current laws using an Accimap analysis. A distinction in the law between the use of hand-held mobile phones, a device that is typically banned for use by drivers worldwide, and the use of other technological devices that are covered by more general laws against 'careless' and/or 'dangerous' driving was found. Historically, individual drivers' have been blamed for distraction, whereas the systems approach shows how current legislation may have created the conditions necessary for driver distraction. Copyright © 2016 Elsevier Ltd. All rights reserved.

  5. Feasibility of new simulation technology to train novice drivers

    DOT National Transportation Integrated Search

    1996-12-01

    This project examined the feasibility of using existing simulation and other electronic device technology with the potential for the safety training of novice drivers. Project activities included: a literature review; site visits and telephone inquir...

  6. Video and non-video feedback interventions for teen drivers.

    DOT National Transportation Integrated Search

    2016-07-01

    In-vehicle feedback technologies, including some that use video, help parents monitor and mentor their young drivers. While different feedback technologies have been shown to reduce some risky driving behaviors, teens and parents cite privacy concern...

  7. Wicked problems in space technology development at NASA

    NASA Astrophysics Data System (ADS)

    Balint, Tibor S.; Stevens, John

    2016-01-01

    Technological innovation is key to enable future space exploration missions at NASA. Technology development, however, is not only driven by performance and resource considerations, but also by a broad range of directly or loosely interconnected factors. These include, among others, strategy, policy and politics at various levels, tactics and programmatics, interactions between stakeholders, resource requirements, performance goals from component to system level, mission infusion targets, portfolio execution and tracking, and technology push or mission pull. Furthermore, at NASA, these influences occur on varying timescales and at diverse geographic locations. Such a complex and interconnected system could impede space technology innovation in this examined segment of the government environment. Hence, understanding the process through NASA's Planning, Programming, Budget and Execution cycle could benefit strategic thinking, planning and execution. Insights could be gained through suitable models, for example assessing the key drivers against the framework of Wicked Problems. This paper discusses NASA specific space technology innovation and innovation barriers in the government environment through the characteristics of Wicked Problems; that is, they do not have right or wrong solutions, only improved outcomes that can be reached through authoritative, competitive, or collaborative means. We will also augment the Wicked Problems model to account for the temporally and spatially coupled, and cyclical nature of this NASA specific case, and propose how appropriate models could improve understanding of the key influencing factors. In turn, such understanding may subsequently lead to reducing innovation barriers, and stimulating technology innovation at NASA. Furthermore, our approach can be adopted for other government-directed environments to gain insights into their structures, hierarchies, operational flow, and interconnections to facilitate circular dialogs towards preferred outcomes.

  8. 49 CFR 390.5 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... history of a driver generated from the driver record, provided to users, such as, drivers or employers... beams or any other future speed measurement technology employed by enforcement personnel to measure the...

  9. State of offsite construction in India-Drivers and barriers

    NASA Astrophysics Data System (ADS)

    Arif, M.; Bendi, D.; Sawhney, A.; Iyer, K. C.

    2012-05-01

    The rapid growth of the construction industry in India has influenced key players in the industry to adopt alternative technologies addressing time, cost and quality. The rising demand in housing, infrastructure and other facilities have further highlighted the need for the construction industry to look at adopting alternate building technologies. Offsite construction has evolved as a panacea to dealing with the under-supply and poor quality in the current age construction industry. Several offsite techniques have been adopted by the construction sector. Although, different forms of offsite techniques have been around for a while but their uptake has been low in the Indian context. This paper presents the perceptions about offsite construction in India and highlights some of the barriers and drivers facing the Indian construction industry. The data was gathered through a survey of 17 high level managers from some of the largest stakeholder organizations of the construction sector in India. The influence of time and cost has been highlighted as a major factor fuelling the adoption of offsite construction. However, the influence of current planning systems and the need for a paradigm shift are some of the prominent barriers towards the adoption of offsite techniques.

  10. Circuits of cancer drivers revealed by convergent misregulation of transcription factor targets across tumor types.

    PubMed

    Gonzalez-Perez, Abel

    2016-01-20

    Large tumor genome sequencing projects have now uncovered a few hundred genes involved in the onset of tumorigenesis, or drivers, in some two dozen malignancies. One of the main challenges emerging from this catalog of drivers is how to make sense of their heterogeneity in most cancer types. This is key not only to understand how carcinogenesis appears and develops in these malignancies to be able to early diagnose them, but also to open up the possibility to employ therapeutic strategies targeting a driver protein to counteract the alteration of another connected driver. Here, I focus on driver transcription factors and their connection to tumorigensis in several tumor types through the alteration of the expression of their targets. First, I explore their involvement in tumorigenesis as mutational drivers in 28 different tumor types. Then, I collect a list of downstream targets of the all driver transcription factors (TFs), and identify which of them exhibit a differential expression upon alterations of driver transcription factors. I identify the subset of targets of each TF most likely mediating the tumorigenic effect of their driver alterations in each tumor type, and explore their overlap. Furthermore, I am able to identify other driver genes that cause tumorigenesis through the alteration of very similar sets of targets. I thus uncover these circuits of connected drivers which cause tumorigenesis through the perturbation of overlapping cellular pathways in a pan-cancer manner across 15 malignancies. The systematic detection of these circuits may be key to propose novel therapeutic strategies indirectly targeting driver alterations in tumors.

  11. BLACKCOMB2: Hardware-software co-design for non-volatile memory in exascale systems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mudge, Trevor

    This work was part of a larger project, Blackcomb2, centered at Oak Ridge National Labs (Jeff Vetter PI) to investigate the opportunities for replacing or supplementing DRAM main memory with nonvolatile memory (NVmemory) in Exascale memory systems. The goal was to reduce the energy consumed by in future supercomputer memory systems and to improve their resiliency. Building on the accomplishments of the original Blackcomb Project, funded in 2010, the goal for Blackcomb2 was to identify, evaluate, and optimize the most promising emerging memory technologies, architecture hardware and software technologies, which are essential to provide the necessary memory capacity, performance, resilience,more » and energy efficiency in Exascale systems. Capacity and energy are the key drivers.« less

  12. Determining the effect of key climate drivers on global hydropower production

    NASA Astrophysics Data System (ADS)

    Galelli, S.; Ng, J. Y.; Lee, D.; Block, P. J.

    2017-12-01

    Accounting for about 17% of total global electrical power production, hydropower is arguably the world's main renewable energy source and a key asset to meet Paris climate agreements. A key component of hydropower production is water availability, which depends on both precipitation and multiple drivers of climate variability acting at different spatial and temporal scales. To understand how these drivers impact global hydropower production, we study the relation between four patterns of ocean-atmosphere climate variability (i.e., El Niño Southern Oscillation, Pacific Decadal Oscillation, North Atlantic Oscillation, and Atlantic Multidecadal Oscillation) and monthly time series of electrical power production for over 1,500 hydropower reservoirs—obtained via simulation with a high-fidelity dam model forced with 20th century climate conditions. Notably significant relationships between electrical power productions and climate variability are found in many climate sensitive regions globally, including North and South America, East Asia, West Africa, and Europe. Coupled interactions from multiple, simultaneous climate drivers are also evaluated. Finally, we highlight the importance of using these climate drivers as an additional source of information within reservoir operating rules where the skillful predictability of inflow exists.

  13. Leveraging Intelligent Vehicle Technologies to Maximize Fuel Economy (Presentation)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gonder, J.

    2011-11-01

    Advancements in vehicle electronics, along with communication and sensing technologies, have led to a growing number of intelligent vehicle applications. Example systems include those for advanced driver information, route planning and prediction, driver assistance, and crash avoidance. The National Renewable Energy Laboratory is exploring ways to leverage intelligent vehicle systems to achieve fuel savings. This presentation discusses several potential applications, such as providing intelligent feedback to drivers on specific ways to improve their driving efficiency, and using information about upcoming driving to optimize electrified vehicle control strategies for maximum energy efficiency and battery life. The talk also covers the potentialmore » of Advanced Driver Assistance Systems (ADAS) and related technologies to deliver significant fuel savings in addition to providing safety and convenience benefits.« less

  14. Compliance with driver's license laws and illegal licensing among commercial bus drivers in Lagos, Nigeria: policy implications and evidence for action.

    PubMed

    Okafor, I P; Odeyemi, K A; Dolapo, D C; Adegbola, A A

    2014-09-01

    To determine the level of compliance with driver's license laws among commercial bus drivers in Lagos, Nigeria. Two intercity motor parks were selected by simple random sampling and all consenting minibus drivers participated in the study. Key Informant Interviews (KIIs) were also conducted with selected officials in the driver training and licensing authorities. Compliance with the minimum age for driving was high (93.6%), so also was having driving test prior to driver's license procurement (83.3%). Formal driver training and VA testing were very low, (26.1% and 32.9% respectively) Overall, only 9.3% of them were found to have fulfilled all the pre-license obligations before obtaining their first driver's license. The odds of a driver with a secondary education having formal driver training is 3.33 times higher than those with no education (OR 3.33, 95% CI 1.01-11.35). Drivers who were 60 years or older were 3.62 times more likely to be compliant than those who were between 20-29 years (OR 3.62, 95% CI 0.56-29.19). For the 98.3% of them who possessed valid licenses, 52.3% of them obtained them illegally. All the key officials saw RTIs as a serious public health problem but faced several challenges in the course of their work. Overall compliance with pre-license regulations was very poor. There is need for a review and strict enforcement of driver's license laws to improve compliance. Also vital are fostering inter-sectoral collaboration and improvement in the operations of all establishments involved in driver training and license procurement in Nigeria.

  15. Objective assessment of the effects of texting while driving: a simulator study.

    PubMed

    Bendak, Salaheddine

    2015-01-01

    Recent advances in electronic communication technology led to many drivers opting to send and receive text messages while driving. This, inevitably, has a potential to distract drivers, impair driving performance and lead to crashes. This study aims to assess the risk involved in texting while driving through assessing the distraction caused and determining the change in key driving performance indicators. Twenty-one paid young male volunteers were recruited to participate in this study. Each participant drove a driving simulator on four different scenarios involving driving while texting and without texting on highways and town roads. Results showed that texting while driving led, on average, to five times more crashes than driving without texting. Due to distraction also, participants unnecessarily crossed lane boundaries and road boundaries more often while texting as compared to driving without texting. Moreover, distraction due to texting led to participants deviating their eyes off the road while texting 15 times per session, on average, more than without texting. Results demonstrated a high-risk level of distraction and clear impairment in drivers' ability to drive safely due to texting. Based on the results, practical recommendations to combat this phenomenon are given.

  16. The Future of Hydropower: Assessing the Impacts of Climate Change, Energy Prices and New Storage Technologies

    NASA Astrophysics Data System (ADS)

    Gaudard, Ludovic; Madani, Kaveh; Romerio, Franco

    2016-04-01

    The future of hydropower depends on various drivers, and in particular on climate change, electricity market evolution and innovation in new storage technologies. Their impacts on the power plants' profitability can widely differ in regards of scale, timing, and probability of occurrence. In this respect, the risk should not be expressed only in terms of expected revenue, but also of uncertainty. These two aspects must be considered to assess the future of hydropower. This presentation discusses the impacts of climate change, electricity market volatility and competing energy storage's technologies and quantifies them in terms of annual revenue. Our simulations integrate a glacio-hydrological model (GERM) with various electricity market data and models (mean reversion and jump diffusion). The medium (2020-50) and long-term (2070-2100) are considered thanks to various greenhouse gas scenarios (A1B, A2 and RCP3PD) and the stochastic approach for the electricity prices. An algorithm named "threshold acceptance" is used to optimize the reservoir operations. The impacts' scale, and the related uncertainties are presented for Mauvoisin, which is a storage-hydropower plant situated in the Swiss Alps, and two generic pure pumped-storage installations, which are assessed with the prices of 17 European electricity markets. The discussion will highlight the key differences between the impacts brought about by the drivers.

  17. Omnichannel Customer Behavior: Key Drivers of Technology Acceptance and Use and Their Effects on Purchase Intention

    PubMed Central

    Juaneda-Ayensa, Emma; Mosquera, Ana; Sierra Murillo, Yolanda

    2016-01-01

    The advance of the Internet and new technologies over the last decade has transformed the retailing panorama. More and more channels are emerging, causing consumers to change their habits and shopping behavior. An omnichannel strategy is a form of retailing that, by enabling real interaction, allows customers to shop across channels anywhere and at any time, thereby providing them with a unique, complete, and seamless shopping experience that breaks down the barriers between channels. This paper aims to identify the factors that influence omnichannel consumers' behavior through their acceptance of and intention to use new technologies during the shopping process. To this end, an original model was developed to explain omnichannel shopping behavior based on the variables used in the UTAUT2 model and two additional factors: personal innovativeness and perceived security. The model was tested with a sample of 628 Spanish customers of the store Zara who had used at least two channels during their most recent shopping journey. The results indicate that the key determinants of purchase intention in an omnichannel context are, in order of importance: personal innovativeness, effort expectancy, and performance expectancy. The theoretical and managerial implications are discussed. PMID:27516749

  18. Omnichannel Customer Behavior: Key Drivers of Technology Acceptance and Use and Their Effects on Purchase Intention.

    PubMed

    Juaneda-Ayensa, Emma; Mosquera, Ana; Sierra Murillo, Yolanda

    2016-01-01

    The advance of the Internet and new technologies over the last decade has transformed the retailing panorama. More and more channels are emerging, causing consumers to change their habits and shopping behavior. An omnichannel strategy is a form of retailing that, by enabling real interaction, allows customers to shop across channels anywhere and at any time, thereby providing them with a unique, complete, and seamless shopping experience that breaks down the barriers between channels. This paper aims to identify the factors that influence omnichannel consumers' behavior through their acceptance of and intention to use new technologies during the shopping process. To this end, an original model was developed to explain omnichannel shopping behavior based on the variables used in the UTAUT2 model and two additional factors: personal innovativeness and perceived security. The model was tested with a sample of 628 Spanish customers of the store Zara who had used at least two channels during their most recent shopping journey. The results indicate that the key determinants of purchase intention in an omnichannel context are, in order of importance: personal innovativeness, effort expectancy, and performance expectancy. The theoretical and managerial implications are discussed.

  19. Volvo drivers' experiences with advanced crash avoidance and related technologies.

    PubMed

    Eichelberger, Angela H; McCartt, Anne T

    2014-01-01

    Crash avoidance technologies can potentially prevent or mitigate many crashes, but their success depends in part on driver acceptance. Owners of 2010-2012 model Volvo vehicles with several technologies were interviewed about their experiences. Interviews were conducted in summer 2012 with 155 owners of vehicles with City Safety as a standard feature; 145 owners with an optional technology package that included adaptive cruise control, distance alert, collision warning with full auto brake (and pedestrian detection on certain models), driver alert control, and lane departure warning; and 172 owners with both City Safety and the technology package. The survey response rates were 21 percent for owners with City Safety, 30 percent for owners with the technology package, and 27 percent for owners with both. Ten percent of owners opted out before the telephone survey began, and 18 percent declined to participate when called. Despite some annoyance, most respondents always leave the systems on, although fewer do so for lane departure warning (59%). For each of the systems, at least 80 percent of respondents with the system would want it on their next vehicle. Many respondents reported safer driving habits with the systems (e.g., following less closely with adaptive cruise control, using turn signals more often with lane departure warning). Fewer respondents reported potentially unsafe behavior, such as allowing the vehicle to brake for them at least some of the time. About one third of respondents experienced autonomous braking when they believed they were at risk of crashing, and about one fifth of respondents thought it had prevented a crash. About one fifth of respondents with the technology package reported that they were confused or misunderstood which safety system had activated in their vehicle. Consistent with the results for early adopters in the previous survey of Volvo and Infiniti owners, the present survey found that driver acceptance of the technologies remains high, although less so for lane departure warning. This study is the first to report drivers' experiences with City Safety, a collision avoidance system provided as standard equipment on certain Volvo 2010-2012 models, and driver acceptance of this system was high, although not to the same extent as the optional forward collision avoidance system. Future research should continue to monitor drivers' experiences with these technologies as they become available in more vehicles.

  20. Using haptic feedback to increase seat belt use of service vehicle drivers.

    DOT National Transportation Integrated Search

    2011-01-01

    This study pilot-tested a new application of a technology-based intervention to increase seat belt use. The technology was based on a : contingency in which unbelted drivers experienced sustained haptic feedback to the gas pedal when they exceeded 25...

  1. Reducing impaired-driving recidivism using advanced vehicle-based alcohol detection systems : a report to Congress

    DOT National Transportation Integrated Search

    2007-12-01

    Vehicle-based alcohol detection systems use technologies designed to detect the presence of alcohol in a driver. Technology suitable for use in all vehicles that will detect an impaired driver faces many challenges including public acceptability, pas...

  2. Design and implementation of a GPS guidance system for agricultural tractors using augmented reality technology.

    PubMed

    Santana-Fernández, Javier; Gómez-Gil, Jaime; del-Pozo-San-Cirilo, Laura

    2010-01-01

    Current commercial tractor guidance systems present to the driver information to perform agricultural tasks in the best way. This information generally includes a treated zones map referenced to the tractor's position. Unlike actual guidance systems where the tractor driver must mentally associate treated zone maps and the plot layout, this paper presents a guidance system that using Augmented Reality (AR) technology, allows the tractor driver to see the real plot though eye monitor glasses with the treated zones in a different color. The paper includes a description of the system hardware and software, a real test done with image captures seen by the tractor driver, and a discussion predicting that the historical evolution of guidance systems could involve the use of AR technology in the agricultural guidance and monitoring systems.

  3. Design and Implementation of a GPS Guidance System for Agricultural Tractors Using Augmented Reality Technology

    PubMed Central

    Santana-Fernández, Javier; Gómez-Gil, Jaime; del-Pozo-San-Cirilo, Laura

    2010-01-01

    Current commercial tractor guidance systems present to the driver information to perform agricultural tasks in the best way. This information generally includes a treated zones map referenced to the tractor’s position. Unlike actual guidance systems where the tractor driver must mentally associate treated zone maps and the plot layout, this paper presents a guidance system that using Augmented Reality (AR) technology, allows the tractor driver to see the real plot though eye monitor glasses with the treated zones in a different color. The paper includes a description of the system hardware and software, a real test done with image captures seen by the tractor driver, and a discussion predicting that the historical evolution of guidance systems could involve the use of AR technology in the agricultural guidance and monitoring systems. PMID:22163479

  4. The use of commercial advertising on large scale electronic billboards for highways and their relation to driver safety and driver distraction, literature review.

    DOT National Transportation Integrated Search

    2008-07-01

    The potential for driver distraction on highways is a major safety concern for state : departments of transportation (DOTs). In the current technological climate, drivers have : the potential to be distracted by cell phones, mp3 players and other med...

  5. Science and Applications Space Platform (SASP) End-to-End Data System Study

    NASA Technical Reports Server (NTRS)

    Crawford, P. R.; Kasulka, L. H.

    1981-01-01

    The capability of present technology and the Tracking and Data Relay Satellite System (TDRSS) to accommodate Science and Applications Space Platforms (SASP) payload user's requirements, maximum service to the user through optimization of the SASP Onboard Command and Data Management System, and the ability and availability of new technology to accommodate the evolution of SASP payloads were assessed. Key technology items identified to accommodate payloads on a SASP were onboard storage devices, multiplexers, and onboard data processors. The primary driver is the limited access to TDRSS for single access channels due to sharing with all the low Earth orbit spacecraft plus shuttle. Advantages of onboard data processing include long term storage of processed data until TRDSS is accessible, thus reducing the loss of data, eliminating large data processing tasks at the ground stations, and providing a more timely access to the data.

  6. High Radiation Resistance IMM Solar Cell

    NASA Technical Reports Server (NTRS)

    Pan, Noren

    2015-01-01

    Due to high launch costs, weight reduction is a key driver for the development of new solar cell technologies suitable for space applications. This project is developing a unique triple-junction inverted metamorphic multijunction (IMM) technology that enables the manufacture of very lightweight, low-cost InGaAsP-based multijunction solar cells. This IMM technology consists of indium (In) and phosphorous (P) solar cell active materials, which are designed to improve the radiation-resistant properties of the triple-junction solar cell while maintaining high efficiency. The intrinsic radiation hardness of InP materials makes them of great interest for building solar cells suitable for deployment in harsh radiation environments, such as medium Earth orbit and missions to the outer planets. NASA Glenn's recently developed epitaxial lift-off (ELO) process also will be applied to this new structure, which will enable the fabrication of the IMM structure without the substrate.

  7. Use, perceptions, and benefits of automotive technologies among aging drivers.

    PubMed

    Eby, David W; Molnar, Lisa J; Zhang, Liang; St Louis, Renée M; Zanier, Nicole; Kostyniuk, Lidia P; Stanciu, Sergiu

    2016-12-01

    Advanced in-vehicle technologies have been proposed as a potential way to keep older adults driving for as long as they can safely do so, by taking into account the common declines in functional abilities experienced by older adults. The purpose of this report was to synthesize the knowledge about older drivers and advanced in-vehicle technologies, focusing on three areas: use (how older drivers use these technologies), perception (what they think about the technologies), and outcomes (the safety and/or comfort benefits of the technologies). Twelve technologies were selected for review and grouped into three categories: crash avoidance systems (lane departure warning, curve speed warning, forward collision warning, blind spot warning, parking assistance); in-vehicle information systems (navigation assistance, intelligent speed adaptation); and other systems (adaptive cruise control, automatic crash notification, night vision enhancement, adaptive headlight, voice activated control). A comprehensive and systematic search was conducted for each technology to collect related publications. 271 articles were included into the final review. Research findings for each of the 12 technologies are synthesized in relation to how older adults use and think about the technologies as well as potential benefits. These results are presented separately for each technology. Can advanced in-vehicle technologies help extend the period over which an older adult can drive safely? This report answers this question with an optimistic "yes." Some of the technologies reviewed in this report have been shown to help older drivers avoid crashes, improve the ease and comfort of driving, and travel to places and at times that they might normally avoid.

  8. Identifying Key Drivers of Return Reversal with Dynamical Bayesian Factor Graph.

    PubMed

    Zhao, Shuai; Tong, Yunhai; Wang, Zitian; Tan, Shaohua

    2016-01-01

    In the stock market, return reversal occurs when investors sell overbought stocks and buy oversold stocks, reversing the stocks' price trends. In this paper, we develop a new method to identify key drivers of return reversal by incorporating a comprehensive set of factors derived from different economic theories into one unified dynamical Bayesian factor graph. We then use the model to depict factor relationships and their dynamics, from which we make some interesting discoveries about the mechanism behind return reversals. Through extensive experiments on the US stock market, we conclude that among the various factors, the liquidity factors consistently emerge as key drivers of return reversal, which is in support of the theory of liquidity effect. Specifically, we find that stocks with high turnover rates or high Amihud illiquidity measures have a greater probability of experiencing return reversals. Apart from the consistent drivers, we find other drivers of return reversal that generally change from year to year, and they serve as important characteristics for evaluating the trends of stock returns. Besides, we also identify some seldom discussed yet enlightening inter-factor relationships, one of which shows that stocks in Finance and Insurance industry are more likely to have high Amihud illiquidity measures in comparison with those in other industries. These conclusions are robust for return reversals under different thresholds.

  9. Implementation of eMental Health care: viewpoints from key informants from organizations and agencies with eHealth mandates.

    PubMed

    Wozney, Lori; Newton, Amanda S; Gehring, Nicole D; Bennett, Kathryn; Huguet, Anna; Hartling, Lisa; Dyson, Michele P; McGrath, Patrick

    2017-06-02

    The use of technology such as computers, tablets, and smartphones to improve access to and the delivery of mental health care (eMental Health care) is growing worldwide. However, despite the rapidly expanding evidence base demonstrating the efficacy of eMental Health care, its implementation in clinical practice and health care systems remains fragmented. To date, no peer-reviewed, key-informant studies have reported on the perspectives of decision-makers concerned with whether and how to implement eMental Health care. From September to November 2015, we conducted 31 interviews with key informants responsible for leadership, policy, research, and/ or information technology in organizations influential in the adoption of technology for eMental Health care. Deductive and inductive thematic analyses of transcripts were conducted using the Behavior Change Wheel as an organizing framework. Frequency and intensity effect sizes were calculated for emerging themes to further explore patterns within the data. Key informant responses (n = 31) representing 6 developed countries and multiple organizations showed consensus on common factors impacting implementation: individual and organizational capacities (e.g., computer literacy skills [patients and providers], knowledge gaps about cyber security, limited knowledge of available services); motivational drivers of technology-based care (e.g., extending care, data analytics); and opportunities for health systems to advance eMental Health care implementation (e.g., intersectoral research, rapid testing cycles, sustainable funding). Frequency effect sizes showed strong associations between implementation and credibility, knowledge, workflow, patient empowerment, electronic medical record (EMR) integration, sustained funding and intersectoral networks. Intensity effect sizes showed the highest concentration of statements (>10% of all comments) related to funding, credibility, knowledge gaps, and patient empowerment. This study provides previously unavailable information about key informant perspectives on eMental Health care implementation. The themes that emerged, namely the need to intensify intersectoral research, measure/monitor readiness to implement, define cost-utility benchmarks, raise awareness about available technologies, and test assumptions that 'proven' technologies will be easily integrated can inform the design and evaluation of eMental Health care implementation models.

  10. What affects public acceptance of recycled and desalinated water?

    PubMed Central

    Dolnicar, Sara; Hurlimann, Anna; Grün, Bettina

    2011-01-01

    This paper identifies factors that are associated with higher levels of public acceptance for recycled and desalinated water. For the first time, a wide range of hypothesized factors, both of socio-demographic and psychographic nature, are included simultaneously. The key results, based on a survey study of about 3000 respondents are that: (1) drivers of the stated likelihood of using desalinated water differ somewhat from drivers of the stated likelihood of using recycled water; (2) positive perceptions of, and knowledge about, the respective water source are key drivers for the stated likelihood of usage; and (3) awareness of water scarcity, as well as prior experience with using water from alternative sources, increases the stated likelihood of use. Practical recommendations for public policy makers, such as key messages to be communicated to the public, are derived. PMID:20950834

  11. Optical coating technology for the EUV

    NASA Astrophysics Data System (ADS)

    Osantowski, J. F.; Keski-Kuha, R. A. M.; Herzig, H.; Toft, A. R.; Gum, J. S.; Fleetwood, C. M.

    Adavaces in optical coating and materials technology are one of the key motivators for the development of missions such as the Far Ultraviolet Spectroscopic Explorer recently selected by NASA for an Explorer class mission in the mid 1990's. The performance of a range of candidate coatings are reviewed for normal-incidence and glancing-incidence applications, and attention is given to strengths and problem areas for their use in space. The importance of recent developments in multilayer films, chemical-vapor deposited SiC (CVD-SiC) mirrors, and SiC films are discussed in the context of EUV instrumentation design. For example, the choice of optical coatings is a design driver for the selection of the average glancing angle for the FUSE telescope, and impacts efficiency, short-wavelength cut-off, and physical size.

  12. Optical coating technology for the EUV

    NASA Technical Reports Server (NTRS)

    Osantowski, J. F.; Keski-Kuha, R. A. M.; Herzig, H.; Toft, A. R.; Gum, J. S.; Fleetwood, C. M.

    1991-01-01

    Advances in optical coating and materials technology are one of the key motivators for the development of missions such as the Far Ultraviolet Spectroscopic Explorer recently selected by NASA for an Explorer class mission in the mid 1990's. The performance of a range of candidate coatings are reviewed for normal-incidence and glancing-incidence applications, and attention is given to strengths and problem areas for their use in space. The importance of recent developments in multilayer films, chemical-vapor deposited SiC (CVD-SiC) mirrors, and SiC films are discussed in the context of EUV instrumentation design. For example, the choice of optical coatings is a design driver for the selection of the average glancing angle for the FUSE telescope, and impacts efficiency, short-wavelength cut-off, and physical size.

  13. Integrating Systems Health Management with Adaptive Controls for a Utility-Scale Wind Turbine

    NASA Technical Reports Server (NTRS)

    Frost, Susan A.; Goebel, Kai; Trinh, Khanh V.; Balas, Mark J.; Frost, Alan M.

    2011-01-01

    Increasing turbine up-time and reducing maintenance costs are key technology drivers for wind turbine operators. Components within wind turbines are subject to considerable stresses due to unpredictable environmental conditions resulting from rapidly changing local dynamics. Systems health management has the aim to assess the state-of-health of components within a wind turbine, to estimate remaining life, and to aid in autonomous decision-making to minimize damage. Advanced adaptive controls can provide the mechanism to enable optimized operations that also provide the enabling technology for Systems Health Management goals. The work reported herein explores the integration of condition monitoring of wind turbine blades with contingency management and adaptive controls. Results are demonstrated using a high fidelity simulator of a utility-scale wind turbine.

  14. Evolving Understanding of the CLL Genome

    PubMed Central

    Gruber, Michaela; Wu, Catherine J.

    2014-01-01

    Over the past few years, massively parallel sequencing technologies have revealed with high resolution the tremendous genetic and epigenetic heterogeneity in chronic lymphocytic leukemia (CLL). We have learned how the molecular architecture differs not only between affected individuals but also within samples and over time. These insights have catalyzed our understanding of the pathobiology of CLL and point to critical signaling pathways in the development and progression of the disease. Several key driver alterations have been identified, which serve to refine prognostic schemata but also inspire the development of new therapeutic strategies. Ongoing advances in technology promise to further elucidate the molecular basis of CLL, and this knowledge is anticipated to aid us in understanding and addressing the clinical challenge presented by the vast variability in the clinical course of patients with CLL. PMID:25048782

  15. Future methods in pharmacy practice research.

    PubMed

    Almarsdottir, A B; Babar, Z U D

    2016-06-01

    This article describes the current and future practice of pharmacy scenario underpinning and guiding this research and then suggests future directions and strategies for such research. First, it sets the scene by discussing the key drivers which could influence the change in pharmacy practice research. These are demographics, technology and professional standards. Second, deriving from this, it seeks to predict and forecast the future shifts in use of methodologies. Third, new research areas and availability of data impacting on future methods are discussed. These include the impact of aging information technology users on healthcare, understanding and responding to cultural and social disparities, implementing multidisciplinary initiatives to improve health care, medicines optimization and predictive risk analysis, and pharmacy as business and health care institution. Finally, implications of the trends for pharmacy practice research methods are discussed.

  16. Towards precision prevention: Technologies for identifying healthy individuals with high risk of disease.

    PubMed

    Nagel, Zachary D; Engelward, Bevin P; Brenner, David J; Begley, Thomas J; Sobol, Robert W; Bielas, Jason H; Stambrook, Peter J; Wei, Qingyi; Hu, Jennifer J; Terry, Mary Beth; Dilworth, Caroline; McAllister, Kimberly A; Reinlib, Les; Worth, Leroy; Shaughnessy, Daniel T

    2017-08-01

    The rise of advanced technologies for characterizing human populations at the molecular level, from sequence to function, is shifting disease prevention paradigms toward personalized strategies. Because minimization of adverse outcomes is a key driver for treatment decisions for diseased populations, developing personalized therapy strategies represent an important dimension of both precision medicine and personalized prevention. In this commentary, we highlight recently developed enabling technologies in the field of DNA damage, DNA repair, and mutagenesis. We propose that omics approaches and functional assays can be integrated into population studies that fuse basic, translational and clinical research with commercial expertise in order to accelerate personalized prevention and treatment of cancer and other diseases linked to aberrant responses to DNA damage. This collaborative approach is generally applicable to efforts to develop data-driven, individualized prevention and treatment strategies for other diseases. We also recommend strategies for maximizing the use of biological samples for epidemiological studies, and for applying emerging technologies to clinical applications. Copyright © 2017 Elsevier B.V. All rights reserved.

  17. Towards precision prevention: Technologies for identifying healthy individuals with high risk of disease

    PubMed Central

    Nagel, Zachary D.; Engelward, Bevin P.; Brenner, David J.; Begley, Thomas J.; Sobol, Robert W.; Bielas, Jason H.; Stambrook, Peter J.; Wei, Qingyi; Hu, Jennifer J.; Terry, Mary Beth; Dilworth, Caroline; McAllister, Kimberly A.; Reinlib, Les; Worth, Leroy; Shaughnessy, Daniel T.

    2018-01-01

    The rise of advanced technologies for characterizing human populations at the molecular level, from sequence to function, is shifting disease prevention paradigms toward personalized strategies. Because minimization of adverse outcomes is a key driver for treatment decisions for diseased populations, developing personalized therapy strategies represent an important dimension of both precision medicine and personalized prevention. In this commentary, we highlight recently developed enabling technologies in the field of DNA damage, DNA repair, and mutagenesis. We propose that omics approaches and functional assays can be integrated into population studies that fuse basic, translational and clinical research with commercial expertise in order to accelerate personalized prevention and treatment of cancer and other diseases linked to aberrant responses to DNA damage. This collaborative approach is generally applicable to efforts to develop data-driven, individualized prevention and treatment strategies for other diseases. We also recommend strategies for maximizing the use of biological samples for epidemiological studies, and for applying emerging technologies to clinical applications. PMID:28458064

  18. Cedar Avenue driver assist system evaluation report.

    DOT National Transportation Integrated Search

    2011-12-01

    This paper summarizes an evaluation of the Driver Assist System (DAS) used by the Minnesota Valley Transit Authority (MTVA) for bus shoulder operations. The DAS is a GPS-based technology suite that provides lane-position feedback to the driver via a ...

  19. Effects of automobile steering characteristics on driver/vehicle system performance in discrete maneuvers

    NASA Technical Reports Server (NTRS)

    Klein, R. H.; Mcruer, D. T.

    1975-01-01

    A series of discrete maneuver tasks were used to evaluate the effects of steering gain and directional mode dynamic parameters on driver/vehicle responses. The importance and ranking of these parameters were evaluated through changes in subjective driver ratings and performance measures obtained from transient maneuvers such as a double lane change, an emergency lane change, and an unexpected obstacle. The unexpected obstacle maneuver proved more sensitive to individual driver differences than to vehicle differences. Results were based on full scale tests with an experienced test driver evaluating many different dynamic configurations plus seventeen ordinary drivers evaluating six key configurations.

  20. Quality of life technology: the state of personal transportation.

    PubMed

    van Roosmalen, Linda; Paquin, Gregory J; Steinfeld, Aaron M

    2010-02-01

    Motor vehicles are a technology that has been embedded in the built environment since the early 1900s. Personal transportation is important for the quality of life of individuals who have disabilities because it gives a feeling of freedom and enables individuals who have mobility impairments to participate in the community. This article describes the evaluation of individuals and their cognitive, sensory, and physical abilities that are important for (safe) driving. A case is made for independent mobility for individuals who have disabilities and elderly individuals by first giving an overview of the functional, cognitive, and sensory abilities that are critical for driving. Second, the types of vehicle modifications and state-of-the-art controls that are available and on the horizon are described and the way in which these technologies are selected to meet driver needs is explained. Requirements for driver safety systems for drivers who remain in their wheelchairs are then discussed. Finally, emerging and innovative driving enhancement systems, such as obstacle avoidance and navigation, are discussed, as are their benefits in helping drivers who have disabilities and elderly drivers to experience safe and independent driving.

  1. A High-Performance Deformable Mirror with Integrated Driver ASIC for Space Based Active Optics

    NASA Astrophysics Data System (ADS)

    Shelton, Chris

    Direct imaging of exoplanets is key to fully understanding these systems through spectroscopy and astrometry. The primary impediment to direct imaging of exoplanets is the extremely high brightness ratio between the planet and its parent star. Direct imaging requires a technique for contrast suppression, which include coronagraphs, and nulling interferometers. Deformable mirrors (DMs) are essential to both of these techniques. With space missions in mind, Microscale is developing a novel DM with direct integration of DM and its electronic control functions in a single small envelope. The Application Specific Integrated Circuit (ASIC) is key to the shrinking of the electronic control functions to a size compatible with direct integration with the DM. Through a NASA SBIR project, Microscale, with JPL oversight, has successfully demonstrated a unique deformable mirror (DM) driver ASIC prototype based on an ultra-low power switch architecture. Microscale calls this the Switch-Mode ASIC, or SM-ASIC, and has characterized it for a key set of performance parameters, and has tested its operation with a variety of actuator loads, such as piezo stack and unimorph, and over a wide temperature range. These tests show the SM-ASIC's capability of supporting active optics in correcting aberrations of a telescope in space. Microscale has also developed DMs to go with the SM-ASIC driver. The latest DM version produced uses small piezo stack elements in an 8x8 array, bonded to a novel silicon facesheet structure fabricated monolithically into a polished mirror on one side and mechanical linkage posts that connect to the piezoelectric stack actuators on the other. In this Supporting Technology proposal we propose to further develop the ASIC-DM and have assembled a very capable team to do so. It will be led by JPL, which has considerable expertise with DMs used in Adaptive Optics systems, with high-contrast imaging systems for exoplanet missions, and with designing DM driver electronics. On its part Microscale will continue its design and fabrication of the ASIC-DM combination. Both the SM-ASIC and the DM are currently at a Technology Readiness Level (TRL) of 3; the major goal of the proposed effort is to raise the TRL of the combined system to 4 by scaling up the array formats and by testing, characterizing, and operating multiple generations of the integrated DM-ASIC systems in a laboratory environment. We propose a three year effort, with these tasks: Year 1: Optimize the influence function of an 8x8 DM for active / adaptive optics, by modeling and fabricating different geometric parameters of the facesheet, with its mechanical linkage posts. Fabricate an SM-ASIC and an 8x8 piezo stack DM, and evaluate their performance. Characterize and optimize the integration processes to achieve a driver/DM combination that can support high contrast imaging of exoplanets. Test the control resolution of the ASIC in driving actuators using a commercial interferometer, to ensure the ASIC can command the piezo stack actuator to nanometer levels. The goal, by year three, is control to a small number of picometers; 10-20 pm (surface) may be a practical goal, while 5 pm is the ultimate goal. Year 2: Fabricate 16x16 piezo stack DMs and matching driver ASICS, and repeat Year 1 tasks with the larger format devices. Year 3: Fabricate 32x32 DMs and SM-ASICs, and repeat Year 1 tasks with the larger format devices. Fabricate versions of the 32x32 devices that can be formed into a 2x2 array, to make a composite 64x64 DM/driver. Fabricate such a composite 64x64 DM/ASIC and evaluate its performance.

  2. High throughput CIGS solar cell fabrication via ultra-thin absorber layer with optical confinement and (Cd, CBD)-free heterojunction partner

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Marsillac, Sylvain

    2015-11-30

    The main objective of this proposal was to use several pathways to reduce the production cost of Cu(In,Ga)Se 2 (CIGS) PV modules and therefore the levelized cost of energy (LCOE) associated with this technology. Three high cost drivers were identified, nominally: 1) Materials cost and availability; 2) Large scale uniformity; 3) Improved throughput These three cost drivers were targeted using the following pathways: 1) Reducing the thickness of the CIGS layer while enhancing materials quality; 2) Developing and applying enhanced in-situ metrology via real time spectroscopic ellipsometry; 3) Looking into alternative heterojunction partner, back contact and anti-reflection (AR) coating Elevenmore » main Tasks were then defined to achieve these goals (5 in Phase 1 and 6 in Phase 2), with 11 Milestones and 2 Go/No-go decision points at the end of Phase 1. The key results are summarized below« less

  3. In-vehicle communication systems: the safety aspect

    PubMed Central

    Pauzie, A

    2002-01-01

    Communication and information technology are developing very rapidly at present. At the same time, the number of older drivers is increasing. When designing systems for elderly drivers, it has been shown that: (1) simplifying a task reduces performance differences between old and young; and (2) the optimization of onboard systems (better legibility and intelligibility of the information, simplified dialogue) in relation to the abilities of elderly drivers benefits the rest of the user population. Elderly people do not automatically reject new information and assistance technologies especially when the systems are user friendly. However, the ergonomics of these new technologies must be studied, with particular attention to the specific needs of the elderly, in order not to marginalize them PMID:12460953

  4. Perceived Drivers and Barriers to the Adoption of eMental Health by Psychologists: The Construction of the Levels of Adoption of eMental Health Model.

    PubMed

    Feijt, Milou A; de Kort, Yvonne Aw; Bongers, Inge Mb; IJsselsteijn, Wijnand A

    2018-04-24

    The internet offers major opportunities in supporting mental health care, and a variety of technology-mediated mental and behavioral health services have been developed. Yet, despite growing evidence for the effectiveness of these services, their acceptance and use in clinical practice remains low. So far, the current literature still lacks a structured insight into the experienced drivers and barriers to the adoption of electronic mental health (eMental health) from the perspective of clinical psychologists. The aim of this study was to gain an in-depth and comprehensive understanding of the drivers and barriers for psychologists in adopting eMental health tools, adding to previous work by also assessing drivers and analyzing relationships among these factors, and subsequently by developing a structured representation of the obtained findings. The study adopted a qualitative descriptive approach consisting of in-depth semistructured interviews with clinical psychologists working in the Netherlands (N=12). On the basis of the findings, a model was constructed that was then examined through a communicative validation. In general, a key driver for psychologists to adopt eMental health is the belief and experience that it can be beneficial to them or their clients. Perceived advantages that are novel to literature include the acceleration of the treatment process, increased intimacy of the therapeutic relationship, and new treatment possibilities due to eMental health. More importantly, a relation was found between the extent to which psychologists have adopted eMental health and the particular drivers and barriers they experience. This differentiation is incorporated in the Levels of Adoption of eMental Health (LAMH) model that was developed during this study to provide a structured representation of the factors that influence the adoption of eMental health. The study identified both barriers and drivers, several of which are new to the literature and found a relationship between the nature and importance of the various drivers and barriers perceived by psychologists and the extent to which they have adopted eMental health. These findings were structured in a conceptual model to further enhance the current understanding. The LAMH model facilitates further research on the process of adopting eMental health, which will subsequently enable targeted recommendations with respect to technology, training, and clinical practice to ensure that mental health care professionals as well as their clients will benefit optimally from the current (and future) range of available eMental health options. ©Milou A Feijt, Yvonne AW de Kort, Inge MB Bongers, Wijnand A IJsselsteijn. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 24.04.2018.

  5. How to identify the key factors that affect driver perception of accident risk. A comparison between Italian and Spanish driver behavior.

    PubMed

    de Oña, Juan; de Oña, Rocio; Eboli, Laura; Forciniti, Carmen; Mazzulla, Gabriella

    2014-12-01

    Road crashes can be caused by different factors, including infrastructure, vehicles, and human variables. Many research studies have focused solely on identifying the key factors that cause road crashes. From these studies, it emerged that human factors have the most relevant impact on accident severity. More specifically, accident severity depends on several factors related directly to the driver, i.e., driving experience, driver's socio-economic characteristics, and driving behavior and attitudes. In this paper, we investigate driver behaviors and attitudes while driving and specifically focus on different methods for identifying the factors that most affect the driver's perception of accident risk. To this end, we designed and conducted a survey in two different European contexts: the city of Cosenza, which is located in the south of Italy, and the city of Granada, which is located in the south of Spain. Samples of drivers were contacted for their opinions on certain aspects of driving rules and attitudes while driving, and different types of questions were addressed to the drivers to assess their judgments of these aspects. Consequently, different methods of data analysis were applied to determine the aspects that heavily influence driver perception of accident risk. An experiment based on the stated preferences (SP) was carried out with the drivers, and the SP data were analyzed using an ordered probit (OP) model. Interesting findings emerged from different analyses of the data and from the comparisons among the data collected in the two different territorial contexts. We found that both Italian and Spanish drivers consider driving in an altered psychophysical state and violating the overtaking rules to be the most risky behaviors. Copyright © 2014 Elsevier Ltd. All rights reserved.

  6. The key role of the meat industry in transformation to a low-carbon, climate resilient, sustainable economy.

    PubMed

    Rijsberman, Frank

    2017-10-01

    Climate change, air pollution and refugees have become key global challenges threatening sustainability of lifestyles, economies and ecosystems. Agri-food systems are the number one driver of environmental change. Livestock production is the world's largest land user, responsible for half of greenhouse gas emissions from agri-food systems, and the source of repeated health crises. Poor diets have become the number one cause of ill health. Recommendations for a healthy diet emphasize plant-based food. Rapidly falling costs in information technology, biotechnology, renewable energy and battery technology will disrupt current energy and transportation systems and offer opportunities for responsible meat production. Growing consumer interest in healthy food, combined with innovative information systems, offer opportunities to create value through quality control and consumer information in integrated value chains. Meat scientists have a major role to play in the necessary transformation of global agri-food systems towards a new model of green economic growth that is climate resilient, sustainable and provides green jobs. Copyright © 2017 Elsevier Ltd. All rights reserved.

  7. Application of Magnetized Target Fusion to High-Energy Space Propulsion

    NASA Technical Reports Server (NTRS)

    Thio, Y. C. F.; Schmidt, G. R.; Kirkpatrick, R. C.; Rodgers, Stephen L. (Technical Monitor)

    2001-01-01

    Most fusion propulsion concepts that have been investigated in the past employ some form of inertial or magnetic confinement. Although the prospective performance of these concepts is excellent, the fusion processes on which these concepts are based still require considerable development before they can be seriously considered for actual applications. Furthermore, these processes are encumbered by the need for sophisticated plasma and power handling systems that are generally quite inefficient and have historically resulted in large, massive spacecraft designs. Here we present a comparatively new approach, Magnetized Target Fusion (MTF), which offers a nearer-term avenue for realizing the tremendous performance benefits of fusion propulsion'. The key advantage of MTF is its less demanding requirements for driver energy and power processing. Additional features include: 1) very low system masses and volumes, 2) high gain and relatively low waste heat, 3) substantial utilization of energy from product neutrons, 4) efficient, low peak-power drivers based on existing pulsed power technology, and 5) very high Isp, specific power and thrust. MTF overcomes many of the problems associated with traditional fusion techniques, thus making it particularly attractive for space applications. Isp greater than 50,000 seconds and specific powers greater than 50 kilowatts/kilogram appear feasible using relatively near-term pulse power and plasma gun technology.

  8. Modeling Human Steering Behavior During Path Following in Teleoperation of Unmanned Ground Vehicles.

    PubMed

    Mirinejad, Hossein; Jayakumar, Paramsothy; Ersal, Tulga

    2018-04-01

    This paper presents a behavioral model representing the human steering performance in teleoperated unmanned ground vehicles (UGVs). Human steering performance in teleoperation is considerably different from the performance in regular onboard driving situations due to significant communication delays in teleoperation systems and limited information human teleoperators receive from the vehicle sensory system. Mathematical models capturing the teleoperation performance are a key to making the development and evaluation of teleoperated UGV technologies fully simulation based and thus more rapid and cost-effective. However, driver models developed for the typical onboard driving case do not readily address this need. To fill the gap, this paper adopts a cognitive model that was originally developed for a typical highway driving scenario and develops a tuning strategy that adjusts the model parameters in the absence of human data to reflect the effect of various latencies and UGV speeds on driver performance in a teleoperated path-following task. Based on data collected from a human subject test study, it is shown that the tuned model can predict both the trend of changes in driver performance for different driving conditions and the best steering performance of human subjects in all driving conditions considered. The proposed model with the tuning strategy has a satisfactory performance in predicting human steering behavior in the task of teleoperated path following of UGVs. The established model is a suited candidate to be used in place of human drivers for simulation-based studies of UGV mobility in teleoperation systems.

  9. A Qualitative Study of Migrant-related Stressors, Psychosocial Outcomes and HIV Risk Behavior among Truck Drivers in Zambia

    PubMed Central

    Ncube, Nomagugu; Simona, Simona J.; Kansankala, Brian; Sinkala, Emmanuel; Raidoo, Jasmin

    2017-01-01

    Truck drivers are part of mobile populations which have been noted as a key population at risk of HIV in Zambia. This study was aimed at 1) determining Potentially Traumatic Events (PTEs), labor migrant-related stressors, psychosocial problems and HIV risk behaviors among truck drivers in Zambia and 2) examining the relationship between PTEs, migrant-related stressors, psychosocial outcomes and HIV sexual risk behavior among truck drivers in Zambia. We conducted fifteen semi-structured interviews with purposively sampled male truck drivers at trucking companies in Lusaka, Zambia. Findings indicate that truck drivers experience multiple stressors and potentially traumatic incidences, including delays and long waiting hours at borders, exposure to crime and violence, poverty, stress related to resisting temptation of sexual interactions with sex workers or migrant women, and job-related safety concerns. Multiple psychosocial problems such as intimate partner violence, loneliness, anxiety and depression-like symptoms were noted. Transactional sex, coupled with inconsistent condom use were identified as HIV sexual risk behaviors. Findings suggest the critical need to develop HIV prevention interventions which account for mobility, potentially traumatic events, psychosocial problems, and the extreme fear of HIV testing among this key population. PMID:27681145

  10. Smart textiles: Challenges and opportunities

    NASA Astrophysics Data System (ADS)

    Cherenack, Kunigunde; van Pieterson, Liesbeth

    2012-11-01

    Smart textiles research represents a new model for generating creative and novel solutions for integrating electronics into unusual environments and will result in new discoveries that push the boundaries of science forward. A key driver for smart textiles research is the fact that both textile and electronics fabrication processes are capable of functionalizing large-area surfaces at very high speeds. In this article we review the history of smart textiles development, introducing the main trends and technological challenges faced in this field. Then, we identify key challenges that are the focus of ongoing research. We then proceed to discuss fundamentals of smart textiles: textile fabrication methods and textile interconnect lines, textile sensor, and output device components and integration of commercial components into textile architectures. Next we discuss representative smart textile systems and finally provide our outlook over the field and a prediction for the future.

  11. How agro-ecological research helps to address food security issues under new IPM and pesticide reduction policies for global crop production systems.

    PubMed

    E Birch, A Nicholas; Begg, Graham S; Squire, Geoffrey R

    2011-06-01

    Drivers behind food security and crop protection issues are discussed in relation to food losses caused by pests. Pests globally consume food estimated to feed an additional one billion people. Key drivers include rapid human population increase, climate change, loss of beneficial on-farm biodiversity, reduction in per capita cropped land, water shortages, and EU pesticide withdrawals under policies relating to 91/414 EEC. IPM (Integrated Pest Management) will be compulsory for all EU agriculture by 2014 and is also being widely adopted globally. IPM offers a 'toolbox' of complementary crop- and region-specific crop protection solutions to address these rising pressures. IPM aims for more sustainable solutions by using complementary technologies. The applied research challenge now is to reduce selection pressure on single solution strategies, by creating additive/synergistic interactions between IPM components. IPM is compatible with organic, conventional, and GM cropping systems and is flexible, allowing regional fine-tuning. It reduces pests below economic thresholds utilizing key 'ecological services', particularly biocontrol. A recent global review demonstrates that IPM can reduce pesticide use and increase yields of most of the major crops studied. Landscape scale 'ecological engineering', together with genetic improvement of new crop varieties, will enhance the durability of pest-resistant cultivars (conventional and GM). IPM will also promote compatibility with semiochemicals, biopesticides, precision pest monitoring tools, and rapid diagnostics. These combined strategies are urgently needed and are best achieved via multi-disciplinary research, including complex spatio-temporal modelling at farm and landscape scales. Integrative and synergistic use of existing and new IPM technologies will help meet future food production needs more sustainably in developed and developing countries, in an era of reduced pesticide availability. Current IPM research gaps are identified and discussed.

  12. What drives technology-based distractions? A structural equation model on social-psychological factors of technology-based driver distraction engagement.

    PubMed

    Chen, Huei-Yen Winnie; Donmez, Birsen

    2016-06-01

    With the proliferation of new mobile and in-vehicle technologies, understanding the motivations behind a driver's voluntary engagement with such technologies is crucial from a safety perspective, yet is complex. Previous literature either surveyed a large number of distractions that may be diverse, or too focuses on one particular activity, such as cell phone use. Further, earlier studies about social-psychological factors underlying driver distraction tend to focus on one or two factors in-depth, and those that examine a more comprehensive set of factors are often limited in their analyses methods. The present work considers a wide array of social-psychological factors within a structural equation model to predict their influence on a focused set of technology-based distractions. A better understanding of these facilitators can enhance the design of distraction mitigation strategies. We analysed survey responses about three technology-based driver distractions: holding phone conversations, manually interacting with cell phones, and adjusting the settings of in-vehicle technology, as well as responses on five social-psychological factors: attitude, descriptive norm, injunctive norm, technology inclination, and a risk/sensation seeking personality. Using data collected from 525 drivers (ages: 18-80), a structural equation model was built to analyse these social-psychological factors as latent variables influencing self-reported engagement in these three technology-based distractions. Self-reported engagement in technology-based distractions was found to be largely influenced by attitudes about the distractions. Personality and social norms also played a significant role, but technology inclination did not. A closer look at two age groups (18-30 and 30+) showed that the effect of social norms, especially of injunctive norm (i.e., perceived approvals), was less prominent in the 30+ age group, while personality remained a significant predictor for the 30+ age group but marginally significant for the younger group. Findings from this work provide insights into the social-psychological factors behind intentional engagement in technology-based distractions and in particular suggesting that these factors may be sensitive to demographic differences. Copyright © 2016. Published by Elsevier Ltd.

  13. [Review of driver fatigue/drowsiness detection methods].

    PubMed

    Wang, Lei; Wu, Xiaojuan; Yu, Mengsun

    2007-02-01

    Driver fatigue/drowsiness is one of the important causes of serious traffic accidents and results in so many people deaths or injuries, but also substantial directly and indirectly economic expenses. Therefore, many countries make great effort on how to detect drowsiness during driving. In this paper, we introduce the recent developments of driver fatigue/drowsiness detection technology of world wide and try to classify the existing methods into several kinds according to different features measured, and analyzed. Finally, the challenges faced to fatigue/drowsiness detection technology and the development trend are presented.

  14. Alcohol involvement in fatal crashes : comparisons among countries

    DOT National Transportation Integrated Search

    2001-06-01

    This report describes the different definitions of key elements in the measurement of alcohol involvement in crashes in 20 different countries. Specifically, countries differ in their definitions of alcohol involvement (e.g., driver only, driver and ...

  15. First Thin Film Festival

    NASA Astrophysics Data System (ADS)

    Samson, Philippe

    2005-05-01

    The constant evolution of the satellite market is asking for better technical performances and reliability for a reduced cost. Solar array is in front line of this challenge.This can be achieved by present technologies progressive improvement in cost reduction or by technological breakthrough.To reach an effective End Of Live performance100 W/kg of solar array is not so easy, even if you suppose that the mass of everything is nothing!Thin film cells are potential candidate to contribute to this challenge with certain confidence level and consequent development plan validation and qualification on ground and flight.Based on a strong flight heritage in flexible Solar Array design, the work has allowed in these last years, to pave the way on road map of thin film technologies . This is encouraged by ESA on many technological contracts put in concurrent engineering.CISG was selected cell and their strategy of design, contributions and results will be presented.Trade-off results and Design to Cost solutions will discussed.Main technical drivers, system design constraints, market access, key technologies needed will be detailed in this paper and the resulting road-map and development plan will be presented.

  16. Role of future scenarios in understanding deep uncertainty in long-term air quality management.

    PubMed

    Gamas, Julia; Dodder, Rebecca; Loughlin, Dan; Gage, Cynthia

    2015-11-01

    The environment and its interactions with human systems, whether economic, social, or political, are complex. Relevant drivers may disrupt system dynamics in unforeseen ways, making it difficult to predict future conditions. This kind of "deep uncertainty" presents a challenge to organizations faced with making decisions about the future, including those involved in air quality management. Scenario Planning is a structured process that involves the development of narratives describing alternative future states of the world, designed to differ with respect to the most critical and uncertain drivers. The resulting scenarios are then used to understand the consequences of those futures and to prepare for them with robust management strategies. We demonstrate a novel air quality management application of Scenario Planning. Through a series of workshops, important air quality drivers were identified. The most critical and uncertain drivers were found to be "technological development" and "change in societal paradigms." These drivers were used as a basis to develop four distinct scenario storylines. The energy and emissions implications of each storyline were then modeled using the MARKAL energy system model. NOx emissions were found to decrease for all scenarios, largely a response to existing air quality regulations, whereas SO2 emissions ranged from 12% greater to 7% lower than 2015 emissions levels. Future-year emissions differed considerably from one scenario to another, however, with key differentiating factors being transition to cleaner fuels and energy demand reductions. Application of scenarios in air quality management provides a structured means of sifting through and understanding the dynamics of the many complex driving forces affecting future air quality. Further, scenarios provide a means to identify opportunities and challenges for future air quality management, as well as a platform for testing the efficacy and robustness of particular management options across wide-ranging conditions.

  17. JPRS Report Science & Technology Europe Twenty-Fourth Isata International Symposium on Automotive Technology and Automation.

    DTIC Science & Technology

    1991-09-05

    34 Learning from Learning : Principles for Supporting Drivers" J A Groeger, MRC Applied Psychology Unit, UK "Argos: A Driver Behaviour Analysis System...Technology (CEST), UK MISCELLANEOUS "Modular Sensor System for Guiding Handling Machines " J Geit and J 423 Heinrich, TZN Forshcungs, FRG "Flexible...PUBLIC TRANSP . MANAa RESEARCH Arrrtympe PARTI "Implementation Strategl»» Systems engineering \\ PART III / Validation through Pilot

  18. Longitudinal control behaviour: Analysis and modelling based on experimental surveys in Italy and the UK.

    PubMed

    Pariota, Luigi; Bifulco, Gennaro Nicola; Galante, Francesco; Montella, Alfonso; Brackstone, Mark

    2016-04-01

    This paper analyses driving behaviour in car-following conditions, based on extensive individual vehicle data collected during experimental field surveys carried out in Italy and the UK. The aim is to contribute to identify simple evidence to be exploited in the ongoing process of driving assistance and automation which, in turn, would reduce rear-end crashes. In particular, identification of differences and similarities in observed car-following behaviours for different samples of drivers could justify common tuning, at a European or worldwide level, of a technological solution aimed at active safety, or, in the event of differences, could suggest the most critical aspects to be taken into account for localisation or customisation of driving assistance solutions. Without intending to be exhaustive, this paper moves one step in this direction. Indeed, driving behaviour and human errors are considered to be among the main crash contributory factors, and a promising approach for safety improvement is the progressive introduction of increasing levels of driving automation in next-generation vehicles, according to the active/preventive safety approach. However, the more advanced the system, the more complex will be the integration in the vehicle, and the interaction with the driver may sometimes become unproductive, or risky, should the driver be removed from the driving control loop. Thus, implementation of these systems will require the interaction of human driving logics with automation logics and then an enhanced ability in modelling drivers' behaviour. This will allow both higher active-safety levels and higher user acceptance to be achieved, thus ensuring that the driver is always in the control loop, even if his/her role is limited to supervising the automatic logic. Currently, the driving mode most targeted by driving assistance systems is longitudinal driving. This is required in various driving conditions, among which car-following assumes key importance because of the huge number of rear-end crashes. The increased availability of lower-cost information and communication technologies (ICTs) has enhanced the possibility of collecting copious and reliable car-following individual vehicle data. In this work, data collected from three different experiments, two carried out in Italy and one in the UK, are analysed and compared. The experiments involved 146 drivers (105 Italian drivers and 41 UK drivers). Data were collected by two instrumented vehicles. Our analysis focused on inter-vehicular spacing in equilibrium car-following conditions. We observed that (i) the adopted equilibrium spacing can be fitted using lognormal distributions, (ii) the adopted equilibrium spacing increases with speed, and (iii) the dispersion between drivers increases with speed. In addition, according to different headway thresholds (up to 1 second) a significant number of potentially dangerous behaviours is observed. Three different car-following paradigms are also applied to each of the experiments, and modelling parameters are calibrated and compared to obtain indirect confirmation about the observed similarities and differences in driving behaviour. Copyright © 2016 Elsevier Ltd. All rights reserved.

  19. Fatigue in Younger and Older Drivers: Effectiveness of an Alertness-Maintaining Task.

    PubMed

    Song, Woojin; Woon, Fu L; Doong, Alice; Persad, Carol; Tijerina, Louis; Pandit, Pooja; Cline, Carol; Giordani, Bruno

    2017-09-01

    The aim of this study was to examine the effects of an alertness-maintaining task (AMT) in older, fatigued drivers. Fatigue during driving increases crash risk, and previous research suggests that alertness and driving in younger adults may be improved using a secondary AMT during boring, fatigue-eliciting drives. However, the potential impact of an AMT on driving has not been investigated in older drivers whose ability to complete dual tasks has been shown to decline and therefore may be negatively affected with an AMT in driving. Younger ( n = 29) and older drivers ( n = 39) participated in a 50-minute simulated drive designed to induce fatigue, followed by four 10-minute sessions alternating between driving with and without an AMT. Younger drivers were significantly more affected by fatigue on driving performance than were older drivers but benefitted significantly from the AMT. Older drivers did not demonstrate increased driver errors with fatigue, and driving did not deteriorate significantly during participation in the AMT condition, although their speed was significantly more variable with the AMT. Consistent with earlier research, an AMT applied during fatiguing driving is effective in improving alertness and reducing driving errors in younger drivers. Importantly, older drivers were relatively unaffected by fatigue, and use of an AMT did not detrimentally affect their driving performance. These results support the potential use of an AMT as a new automotive technology to improve fatigue and promote driver safety, though the benefits of such technology may differ between different age groups.

  20. 75 FR 38595 - Guidance to States Regarding Driver History Record Information Security, Continuity of Operation...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-02

    ... Standards and Technology's (NIST) Computer Security Division maintains a Computer Security Resource Center... Regarding Driver History Record Information Security, Continuity of Operation Planning, and Disaster... (SDLAs) to support their efforts at maintaining the security of information contained in the driver...

  1. Identifying Key Drivers of Return Reversal with Dynamical Bayesian Factor Graph

    PubMed Central

    Zhao, Shuai; Tong, Yunhai; Wang, Zitian; Tan, Shaohua

    2016-01-01

    In the stock market, return reversal occurs when investors sell overbought stocks and buy oversold stocks, reversing the stocks’ price trends. In this paper, we develop a new method to identify key drivers of return reversal by incorporating a comprehensive set of factors derived from different economic theories into one unified dynamical Bayesian factor graph. We then use the model to depict factor relationships and their dynamics, from which we make some interesting discoveries about the mechanism behind return reversals. Through extensive experiments on the US stock market, we conclude that among the various factors, the liquidity factors consistently emerge as key drivers of return reversal, which is in support of the theory of liquidity effect. Specifically, we find that stocks with high turnover rates or high Amihud illiquidity measures have a greater probability of experiencing return reversals. Apart from the consistent drivers, we find other drivers of return reversal that generally change from year to year, and they serve as important characteristics for evaluating the trends of stock returns. Besides, we also identify some seldom discussed yet enlightening inter-factor relationships, one of which shows that stocks in Finance and Insurance industry are more likely to have high Amihud illiquidity measures in comparison with those in other industries. These conclusions are robust for return reversals under different thresholds. PMID:27893780

  2. Determining the key drivers and mitigating factors that influence the role of the Nurse and/or Midwife Consultant: a cross-sectional survey.

    PubMed

    Fernandez, Ritin S; Sheppard-Law, Suzanne; Manning, Vicki

    2017-06-01

    Globally, many nurses and midwives are working at an advanced practice level. The role of a Nurse and/or Midwife Consultant encompasses a diverse and complex interaction between five specified domains namely Clinical Service and Consultancy, Clinical Leadership, Research, Education, and Clinical Services Planning and Management. The objective of this replication study was to identify the key drivers and mitigating factors that impact the role of Australian Nurse and/or Midwife Consultants. Cross-sectional survey. The study was conducted in a large metropolitan health district in Sydney, Australia. Participants for this study consisted of all Nurse and/or Midwife Consultants working within a health district in New South Wales (NSW). Data were collected by an anonymous online survey. Key drivers and mitigating factors perceived to influence their role were identified using previously implemented instruments. Data were analysed using SPSS version 21. Responses were obtained from 122 Nurse and/or Midwife Consultants. The number of years of experience as a Nurse and/or Midwife Consultant ranged from 6 months to 25.5 years. Personal attributes which included personal motivation and own communication skills were identified as key drivers to role performance with a mean score of 7.7±0.6. Other key drivers included peer support, organisational culture, personal attributes, professional learning, Nurse and/or Midwife Consultant experience, and collaborative relationships. Of the 14 mitigating factors to the role, the most common factors were lack of resources to set up and develop the role (2.6 ± 0.9), lack of secretarial support (2.6 ± 1.1), lack of managerial support (2.45 ± 1.1), and lack of understanding of the role by other health professionals (2.40 ± 0.8). Understanding the key drivers and mitigating factors that influence the role of the Nurse and/or Midwife Consultant is important for healthcare managers. Given the changing landscape of nursing and midwifery practice, organisational strategies to provide ongoing support to address the mitigating factors are urgently needed. It is pivotal that nursing management implement strategies to empower Nurse and/or Midwife Consultants to perform and reach their potential to deliver advanced nursing care.

  3. Technology transfer methodology

    NASA Technical Reports Server (NTRS)

    Labotz, Rich

    1991-01-01

    Information on technology transfer methodology is given in viewgraph form. Topics covered include problems in economics, technology drivers, inhibitors to using improved technology in development, technology application opportunities, and co-sponsorship of technology.

  4. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Soer, Wouter

    LED luminaires have seen dramatic changes in cost breakdown over the past few years. The LED component cost, which until recently was the dominant portion of luminaire cost, has fallen to a level of the same order as the other luminaire components, such as the driver, housing, optics etc. With the current state of the technology, further luminaire performance improvement and cost reduction is realized most effectively by optimization of the whole system, rather than a single component. This project focuses on improving the integration between LEDs and drivers. Lumileds has developed a light engine platform based on low-cost high-powermore » LEDs and driver topologies optimized for integration with these LEDs on a single substrate. The integration of driver and LEDs enables an estimated luminaire cost reduction of about 25% for targeted applications, mostly due to significant reductions in driver and housing cost. The high-power LEDs are based on Lumileds’ patterned sapphire substrate flip-chip (PSS-FC) technology, affording reduced die fabrication and packaging cost compared to existing technology. Two general versions of PSS-FC die were developed in order to create the desired voltage and flux increments for driver integration: (i) small single-junction die (0.5 mm 2), optimal for distributed lighting applications, and (ii) larger multi-junction die (2 mm 2 and 4 mm 2) for high-power directional applications. Two driver topologies were developed: a tapped linear driver topology and a single-stage switch-mode topology, taking advantage of the flexible voltage configurations of the new PSS-FC die and the simplification opportunities enabled by integration of LEDs and driver on the same board. A prototype light engine was developed for an outdoor “core module” application based on the multi-junction PSS-FC die and the single-stage switch-mode driver. The light engine meets the project efficacy target of 128 lm/W at a luminous flux greater than 4100 lm, a correlated color temperature (CCT) of 4000K and a color rendering index (CRI) greater than 70.« less

  5. Prevalence and characteristics of road traffic injuries among young drivers in Oman, 2009-2011.

    PubMed

    Al Reesi, Hamed; Al Maniri, Abdullah; Adawi, Samir Al; Davey, Jeremy; Armstrong, Kerry; Edwards, Jason

    2016-07-03

    Studies from different parts of the world have indicated that the impact of road traffic incidents disproportionally affects young adults. Few known studies have been forthcoming from Arabian Gulf countries. Within Oman, a high proportion of the population is under the age of 20. Coupled with the drastic increase in motorization in recent years, there is a need to understand the state of road safety among young people in Oman. The current research aimed to explore the prevalence and characteristics of road traffic injuries among young drivers aged 17-25 years. Crash data from 2009 to 2011 were extracted from the Directorate General of Traffic, Royal Oman Police (ROP) database in Oman. The data were analyzed to explore the impact of road crashes on young people (17-25 years), the characteristics of young driver crashes, and how these differ from older drivers and to identify key predictors of fatalities in young driver crashes. Overall, young people were overrepresented in injuries and fatalities within the sample time period. Though it is true that many young people in crashes were driving at the time, it was also evident that young people were often victims in a crash caused by someone else. Thus, to reduce the impact of road crashes on young people, there is a need to generally address road safety within Oman. When young drivers were involved in crashes they were predominantly male. The types of crashes these drivers have can be broadly attributed to risk taking and inexperience. Speeding and nighttime driving were the key risk factors for fatalities. The results highlight the need to address young driver safety in Oman. From these findings, the introduction of a graduated driver licensing system with nighttime driving restrictions could significantly improve young driver safety.

  6. Driver acceptance of commercial vehicle operations (CVO) technology in the motor carrier environment. Executive summary, Critical issues relating to acceptance of technology by interstate truck and bus drivers

    DOT National Transportation Integrated Search

    2000-05-01

    The California database incorporated in the Highway Safety Information System (HSIS) is derived from the California TASAS (Traffic Accident Surveillance and Analysis System). The system, maintained by the Traffic Operations Office of Caltrans, is a m...

  7. First direct landscape-scale measurement of tropical rain forest Leaf Area Index, a key driver of global primary productivity

    Treesearch

    David B. Clark; Paulo C. Olivas; Steven F. Oberbauer; Deborah A. Clark; Michael G. Ryan

    2008-01-01

    Leaf Area Index (leaf area per unit ground area, LAI) is a key driver of forest productivity but has never previously been measured directly at the landscape scale in tropical rain forest (TRF). We used a modular tower and stratified random sampling to harvest all foliage from forest floor to canopy top in 55 vertical transects (4.6 m2) across 500 ha of old growth in...

  8. Taking The Guesswork Out of Strategy

    DTIC Science & Technology

    2011-06-18

    Intensity Conflict & Law Enforcement, Vol. 9, No.2 (Summer 2000): 63-69. 5 professionals avoid focusing on irrelevant or false strategy drivers and...to engage Africa on the security front is paramount to keeping America safe. Prosperity is another driver for strategy with Africa. Globalization...this front. Last, international order is yet another key driver to why strategy is important. The HIV/AIDS epidemic in Africa extends beyond its

  9. Drivers Impacting the Adoption of Sustainable Agricultural Management Practices and Production Systems of the Northeast and Southeast U.S

    USDA-ARS?s Scientific Manuscript database

    Agricultural production responds to economic, social, environmental, and technological drivers operating both internal and external to the production system. These drivers influence producers’ decision making processes, and act to shape the individual production systems through modification of produ...

  10. Interferometer design and controls for pulse stacking in high power fiber lasers

    NASA Astrophysics Data System (ADS)

    Wilcox, Russell; Yang, Yawei; Dahlen, Dar; Xu, Yilun; Huang, Gang; Qiang, Du; Doolittle, Lawrence; Byrd, John; Leemans, Wim; Ruppe, John; Zhou, Tong; Sheikhsofla, Morteza; Nees, John; Galvanauskas, Almantas; Dawson, Jay; Chen, Diana; Pax, Paul

    2017-03-01

    In order to develop a design for a laser-plasma accelerator (LPA) driver, we demonstrate key technologies that enable fiber lasers to produce high energy, ultrafast pulses. These technologies must be scalable, and operate in the presence of thermal drift, acoustic noise, and other perturbations typical of an operating system. We show that coherent pulse stacking (CPS), which requires optical interferometers, can be made robust by image-relaying, multipass optical cavities, and by optical phase control schemes that sense pulse train amplitudes from each cavity. A four-stage pulse stacking system using image-relaying cavities is controlled for 14 hours using a pulse-pattern sensing algorithm. For coherent addition of simultaneous ultrafast pulses, we introduce a new scheme using diffractive optics, and show experimentally that four pulses can be added while a preserving pulse width of 128 fs.

  11. Low-Cost, Light Weight, Thin Film Solar Concentrator

    NASA Technical Reports Server (NTRS)

    Ganapathi, G.; Palisoc, A.; Nesmith, B.; Greschik, G.; Gidanian, K.; Kindler, A.

    2013-01-01

    This research addresses a cost barrier towards achieving a solar thermal collector system with an installed cost of $75/sq m and meet the Department of Energy's (DOE's) performance targets for optical errors, operations during windy conditions and lifetime. Current concentrators can cost as much as 40-50% of the total installed costs for a CSP plant. In order to reduce the costs from current $200-$250/sq m, it is important to focus on the overall system. The reflector surface is a key cost driver, and our film-based polymer reflector will help significantly in achieving DOE's cost target of $75/sq m. The ease of manufacturability, installation and replacement make this technology a compelling one to develop. This technology can be easily modified for a variety of CSP options including heliostats, parabolic dishes and parabolic troughs.

  12. A Perspective on Science and Research in the Environmental Consulting Industry

    NASA Astrophysics Data System (ADS)

    Stephens, D. B.

    2005-12-01

    Substantial growth in the hydrogeology field has occurred in response to federal regulations of the 1970s and 1980s dealing with water quality. The regulations led to increasing student applications, more universities offering programs in hydrogeology, and increased research support. With no new regulatory drivers and diminished perceived imminent threats to human health and the environment in recent years, the field of hydrogeology appears to have matured. An enormous amount of information, new technology, and new analytical tools have overwhelmed regulators and the regulated community. Although there appear to be many areas yet to explore, some of the more theoretical developments may be perceived by end users as having limited practical value or little immediate impact to solve existing problems. A key challenge is to put current theory and state of art technology into practice.

  13. Understanding the Long Run Determinants of Land Use in Global Crop Production

    NASA Astrophysics Data System (ADS)

    Baldos, U. C.; Hertel, T. W.

    2011-12-01

    Cropland cover is expected to increase in the future given the projected growth on global demand for crops. Over the past century, crop demand has largely been driven by food demands, which were, in turn driven by a combination of rising population growth and increased per capita incomes, with the former dominating. However, with population growth slowing, and incomes rising more strongly in the developing world - where dietary upgrading is a significant factor - income growth has emerged as a relatively more significant driver of total food demand. At the same time, renewable energy policies across the world have introduced a new, dynamic element to the industrial demand for cropland. However, the drivers of long run cropland use are not limited to those directly related to crop demand. New trends suggest that crop yield growth may be slowing in critical breadbaskets around the world. In addition, some agricultural lands have been lost to urbanization and soil degradation. There is also a growing interest in setting aside land for biodiversity. Finally, there is considerable interest in terrestrial carbon sequestration which could place important new demands on the world's croplands. The co-existence of so many competing factors poses a challenge for properly assessing the long-run global supply and demand for croplands in 2050. In this paper, we quantify the contributions of each of these key drivers to the long-run global cropland use using a partial equilibrium model of global agriculture. To implement the model, we also construct a global database for key land use, agricultural and socio-economic variables from several sources. Our analysis starts with validation of the model over an historical period from 2001 up to 2007-05 (5 years). The model's prediction regarding cropland use is slightly lower than the observed change (+5.8% vs. +8.3%). Decomposition of the drivers of land use change shows that income growth (+3.9%) has a larger impact than population growth (+1.6%), biofuels (+0.2%) and urbanization (-0.3%). Technological change in crop, livestock and processed food production also have a modest impact on global cropland use over this historical period (+0.8%, -0.3% and +0.1%, respectively). We then turn our attention to projections of global land use over the coming decade. Here we project continued expansion in global cropland (13.7%). We then decompose the drivers of this projected change in land use. For example, if population grows at projected rates and yields grow at recent historical rates, then projected cropland use rises by just 1.7%. If we add urbanization, then global cropland use is slightly reduced (+1.5%). Because of the magnitude of the projected production targets, adding biofuels boosts global cropland use strongly (+4.2%) when added to the preceding factors. Adding technological change in the livestock and food processing sectors, as well as growth in per capita incomes boosts projected cropland use to 13.7%. In short, income growth is likely to be the critical driver of global cropland change in the future.

  14. Improving the Efficiency and Quality of the Value Assessment Process for Companion Diagnostic Tests: The Companion test Assessment Tool (CAT).

    PubMed

    Canestaro, William J; Pritchard, Daryl E; Garrison, Louis P; Dubois, Robert; Veenstra, David L

    2015-08-01

    Companion diagnostic tests (CDTs) have emerged as a vital technology in the effective use of an increasing number of targeted drug therapies. Although CDTs can offer a multitude of potential benefits, assessing their value within a health technology appraisal process can be challenging because of a complex array of factors that influence clinical and economic outcomes. To develop a user-friendly tool to assist managed care and other health care decision makers in screening companion tests and determining whether an intensive technology review is necessary and, if so, where the review should be focused to improve efficiency. First, we conducted a systematic literature review of CDT cost-effectiveness studies to identify value drivers. Second, we conducted key informant interviews with a diverse group of stakeholders to elicit feedback and solicit any additional value drivers and identify desirable attributes for an evidence review tool. A draft tool was developed based on this information that captured value drivers, usability features, and had a particular focus on practical use by nonexperts. Finally, the tool was pilot tested with test developers and managed care evidence evaluators to assess face-validity and usability. The tool was also evaluated using several diverse examples of existing companion diagnostics and refined accordingly. We identified 65 cost-effectiveness studies of companion diagnostic technologies. The following factors were most commonly identified as value drivers from our literature review: clinical validity of testing; efficacy, safety, and cost of baseline and alternative treatments; cost and mortality of health states; and biomarker prevalence and testing cost. Stakeholders identified the following additional factors that they believed influenced the overall value of a companion test: regulatory status, actionability, utility, and market penetration. These factors were used to maximize the efficiency of the evidence review process. Stakeholders also stated that a tool should be easy to use and time efficient. Cognitive interviews with stakeholders led to minor changes in the draft tool to improve usability and relevance. The final tool consisted of 4 sections: (1) eligibility for review (2 questions), (2) prioritization of review (3 questions), (3) clinical review (3 questions), and (4) economic review (5 questions). Although the evaluation of CDTs can be challenging because of limited evidence and the added complexity of incorporating a diagnostic test into drug treatment decisions, using a pragmatic tool to identify tests that do not need extensive evaluation may improve the efficiency and effectiveness of CDT value assessments.

  15. Considerations Regarding the Development of an Environmental Control and Life Support System for Lunar Surface Applications

    NASA Technical Reports Server (NTRS)

    Bagdigian, Robert M.

    2008-01-01

    NASA is engaged in early architectural analyses and trade studies aimed at identifying requirements, predicting performance and resource needs, characterizing mission constraints and sensitivities, and guiding technology development planning needed to conduct a successful human exploration campaign of the lunar surface. Conceptual designs and resource estimates for environmental control and life support systems (ECLSS) within pressurized lunar surface habitats and rovers have been considered and compared in order to support these lunar campaign studies. This paper will summarize those concepts and some of the more noteworthy considerations that will likely remain as key drivers in the evolution of the lunar surface ECLSS architecture.

  16. Identification of mutated driver pathways in cancer using a multi-objective optimization model.

    PubMed

    Zheng, Chun-Hou; Yang, Wu; Chong, Yan-Wen; Xia, Jun-Feng

    2016-05-01

    New-generation high-throughput technologies, including next-generation sequencing technology, have been extensively applied to solve biological problems. As a result, large cancer genomics projects such as the Cancer Genome Atlas (TCGA) and the International Cancer Genome Consortium are producing large amount of rich and diverse data in multiple cancer types. The identification of mutated driver genes and driver pathways from these data is a significant challenge. Genome aberrations in cancer cells can be divided into two types: random 'passenger mutation' and functional 'driver mutation'. In this paper, we introduced a Multi-objective Optimization model based on a Genetic Algorithm (MOGA) to solve the maximum weight submatrix problem, which can be employed to identify driver genes and driver pathways promoting cancer proliferation. The maximum weight submatrix problem defined to find mutated driver pathways is based on two specific properties, i.e., high coverage and high exclusivity. The multi-objective optimization model can adjust the trade-off between high coverage and high exclusivity. We proposed an integrative model by combining gene expression data and mutation data to improve the performance of the MOGA algorithm in a biological context. Copyright © 2016 Elsevier Ltd. All rights reserved.

  17. Implementation of safety driving system using e-health and telematics technology.

    PubMed

    Lee, Youngbum; Lee, Myoungho

    2008-08-01

    This research aimed to develop a safety driving system using e-health and telematics technology. Biosignal sensors were installed in an automobile to check the driver's health status with an automatic diagnosis system providing health information to the driver. Measured data were sent to the e-health center through a telematics device, and a medical doctor analyzed these data, sending diagnosis and prescription information to the driver. This system recognizes the driver's sleeping, drinking impairment, excitability, and fatigue using biosensors. The system initially provides alerts in the automobile. It also controls the driving environment in the car, searches for a highway service area using Global Positioning System (GPS), and provides additional information for safety driving. If a car accident has occurred, it makes an emergency call to the nearest hospital, emergency center, and insurance company. A conceptual and prototype model for an imbedded system is presented with initial data for driver condition. Such a system could prevent car accidents caused by drivers driving while intoxicated and falling asleep at the wheel using the driver's biosignals measured by biosensors. The system can provide various e-health services using a telematics system to enhance the technical compatibility of the automobile.

  18. Fusion of Optimized Indicators from Advanced Driver Assistance Systems (ADAS) for Driver Drowsiness Detection

    PubMed Central

    Daza, Iván G.; Bergasa, Luis M.; Bronte, Sebastián; Yebes, J. Javier; Almazán, Javier; Arroyo, Roberto

    2014-01-01

    This paper presents a non-intrusive approach for monitoring driver drowsiness using the fusion of several optimized indicators based on driver physical and driving performance measures, obtained from ADAS (Advanced Driver Assistant Systems) in simulated conditions. The paper is focused on real-time drowsiness detection technology rather than on long-term sleep/awake regulation prediction technology. We have developed our own vision system in order to obtain robust and optimized driver indicators able to be used in simulators and future real environments. These indicators are principally based on driver physical and driving performance skills. The fusion of several indicators, proposed in the literature, is evaluated using a neural network and a stochastic optimization method to obtain the best combination. We propose a new method for ground-truth generation based on a supervised Karolinska Sleepiness Scale (KSS). An extensive evaluation of indicators, derived from trials over a third generation simulator with several test subjects during different driving sessions, was performed. The main conclusions about the performance of single indicators and the best combinations of them are included, as well as the future works derived from this study. PMID:24412904

  19. A Flexible Socioeconomic Scenarios Framework for the Study of Plausible Arctic Futures

    NASA Astrophysics Data System (ADS)

    Reissell, A. K.; Peters, G. P.; Riahi, K.; Kroglund, M.; Lovecraft, A. L.; Nilsson, A. E.; Preston, B. L.; van Ruijven, B. J.

    2016-12-01

    Future developments of the Arctic region are associated with different drivers of change - climate, environmental, and socio-economic - and their interactions, and are highly uncertain. The uncertainty poses challenges for decision-making, calling for development of new analytical frameworks. Scenarios - coherent narratives describing potential futures, pathways to futures, and drivers of change along the way - can be used to explore the consequences of the key uncertainties, particularly in the long-term. In a participatory scenarios workshop, we used both top-down and bottom-up approaches for the development of a flexible socioeconomic scenarios framework. The top-down approach was linked to the global Integrated Assessment Modeling framework and its Shared Socio-Economic Pathways (SSPs), developing an Arctic extension of the set of five storylines on the main socioeconomic uncertainties in global climate change research. The bottom-up approach included participatory development of narratives originating from within the Arctic region. For extension of global SSPs to the regional level, we compared the key elements in the global SSPs (Population, Human Development, Economy & Lifestyle, Policies & Institutions, Technology, and Environment & Natural Resources) and key elements in the Arctic. Additional key elements for the Arctic scenarios include, for example, seasonal migration, the large role of traditional knowledge and culture, mixed economy, nested governance structure, human and environmental security, quality of infrastructure. The bottom-up derived results suggested that the scenarios developed independent of the SSPs could be mapped back to the SSPs to demonstrate consistency with respect to representing similar boundary conditions. The two approaches are complimentary, as the top-down approach can be used to set the global socio-economic and climate boundary conditions, and the bottom-up approach providing the regional context. One key uncertainty and driving force is the demand for resources (global or regional) that was mapped against the role of governance as well as adaptive and transformative capacity among actors within the Arctic. Resources demand has significant influence on the society, culture, economy and environment of the Arctic.

  20. Modulators of mercury risk to wildlife and humans in the context of rapid global change

    USGS Publications Warehouse

    Eagles-Smith, Collin A.; Silbergeld, Ellen K.; Basu, Niladri; Bustamante, Paco; Diaz-Barriga, Fernando; Hopkins, William A.; Kidd, Karen A.; Nyland, Jennifer F.

    2018-01-01

    Environmental mercury (Hg) contamination is an urgent global health threat. The complexity of Hg in the environment can hinder accurate determination of ecological and human health risks, particularly within the context of the rapid global changes that are altering many ecological processes, socioeconomic patterns, and other factors like infectious disease incidence, which can affect Hg exposures and health outcomes. However, the success of global Hg-reduction efforts depends on accurate assessments of their effectiveness in reducing health risks. In this paper, we examine the role that key extrinsic and intrinsic drivers play on several aspects of Hg risk to humans and organisms in the environment. We do so within three key domains of ecological and human health risk. First, we examine how extrinsic global change drivers influence pathways of Hg bioaccumulation and biomagnification through food webs. Next, we describe how extrinsic socioeconomic drivers at a global scale, and intrinsic individual-level drivers, influence human Hg exposure. Finally, we address how the adverse health effects of Hg in humans and wildlife are modulated by a range of extrinsic and intrinsic drivers within the context of rapid global change. Incorporating components of these three domains into research and monitoring will facilitate a more holistic understanding of how ecological and societal drivers interact to influence Hg health risks.

  1. Examining Tensions That Affect the Evaluation of Technology in Health Care: Considerations for System Decision Makers From the Perspective of Industry and Evaluators

    PubMed Central

    Shaw, James; Wallace, Ross; Bhattacharyya, Onil; Bhatia, R Sacha; Jamieson, Trevor

    2017-01-01

    Virtual technologies have the potential to mitigate a range of challenges for health care systems. Despite the widespread use of mobile devices in everyday life, they currently have a limited role in health service delivery and clinical care. Efforts to integrate the fast-paced consumer technology market with health care delivery exposes tensions among patients, providers, vendors, evaluators, and system decision makers. This paper explores the key tensions between the high bar for evidence prior to market approval that guides health care regulatory decisions and the “fail fast” reality of the technology industry. We examine three core tensions: balancing user needs versus system needs, rigor versus responsiveness, and the role of pre- versus postmarket evidence generation. We use these to elaborate on the structure and appropriateness of evaluation mechanisms for virtual care solutions. Virtual technologies provide a foundation for personalized, patient-centered medicine on the user side, coupled with a broader understanding of impact on the system side. However, mechanisms for stakeholder discussion are needed to clarify the nature of the health technology marketplace and the drivers of evaluation priorities. PMID:29222075

  2. A Compact Low-Power Driver Array for VCSELs in 65-nm CMOS Technology

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zeng, Zhiyao; Sun, Kexu; Wang, Guanhua

    This article presents a compact low-power 4 x 10 Gb/s quad-driver module for Vertical-Cavity Surface-Emitting Laser (VCSEL) arrays in a 65 nm CMOS technology. The side-by-side drivers can be directly wire bonded to the VCSEL diode array, supporting up to 4 channels. To increase the bandwidth of the driver, an internal feed-forward path is added for pole-zero cancellation, without increasing the power consumption. An edge-configurable pre-emphasis technique is proposed to achieve high bandwidth and minimize the asymmetry of the fall and rise times of the driver output current. Measurement results demonstrate a RMS jitter of 0.68 ps for 10 Gb/smore » operation. Tests demonstrate negligible crosstalk between channels. Under irradiation, the modulation amplitude degrades less than 5% up to 300 Mrad ionizing dose. Finally, the area of the quaddriver array is 500 μm by 1000 μm and the total power consumption for the entire driver array chip is 130 mW for the typical current setting.« less

  3. A Compact Low-Power Driver Array for VCSELs in 65-nm CMOS Technology

    DOE PAGES

    Zeng, Zhiyao; Sun, Kexu; Wang, Guanhua; ...

    2017-05-08

    This article presents a compact low-power 4 x 10 Gb/s quad-driver module for Vertical-Cavity Surface-Emitting Laser (VCSEL) arrays in a 65 nm CMOS technology. The side-by-side drivers can be directly wire bonded to the VCSEL diode array, supporting up to 4 channels. To increase the bandwidth of the driver, an internal feed-forward path is added for pole-zero cancellation, without increasing the power consumption. An edge-configurable pre-emphasis technique is proposed to achieve high bandwidth and minimize the asymmetry of the fall and rise times of the driver output current. Measurement results demonstrate a RMS jitter of 0.68 ps for 10 Gb/smore » operation. Tests demonstrate negligible crosstalk between channels. Under irradiation, the modulation amplitude degrades less than 5% up to 300 Mrad ionizing dose. Finally, the area of the quaddriver array is 500 μm by 1000 μm and the total power consumption for the entire driver array chip is 130 mW for the typical current setting.« less

  4. Costs of a work-family intervention: evidence from the work, family, and health network.

    PubMed

    Barbosa, Carolina; Bray, Jeremy W; Brockwood, Krista; Reeves, Daniel

    2014-01-01

    To estimate the cost to the workplace of implementing initiatives to reduce work-family conflict. Prospective cost analysis conducted alongside a group-randomized multisite controlled experimental study, using a microcosting approach. An information technology firm. Employees (n = 1004) and managers (n = 141) randomized to the intervention arm. STAR (Start. Transform. Achieve. Results.) to enhance employees' control over their work time, increase supervisor support for employees to manage work and family responsibilities, and reorient the culture toward results. A taxonomy of activities related to customization, start-up, and implementation was developed. Resource use and unit costs were estimated for each activity, excluding research-related activities. Economic costing approach (accounting and opportunity costs). Sensitivity analyses on intervention costs. The total cost of STAR was $709,654, of which $389,717 was labor costs and $319,937 nonlabor costs (including $313,877 for intervention contract). The cost per employee participation in the intervention was $340 (95% confidence interval: $330-$351); $597 ($561-$634) for managers and $300 ($292-$308) for other employees (2011 prices). A detailed activity costing approach allows for more accurate cost estimates and identifies key drivers of cost. The key cost driver was employees' time spent on receiving the intervention. Ignoring this cost, which is usual in studies that cost workplace interventions, would seriously underestimate the cost of a workplace initiative.

  5. Driver trust in five driver assistance technologies following real-world use in four production vehicles.

    PubMed

    Kidd, David G; Cicchino, Jessica B; Reagan, Ian J; Kerfoot, Laura B

    2017-05-29

    Information about drivers' experiences with driver assistance technologies in real driving conditions is sparse. This study characterized driver interactions with forward collision warning, adaptive cruise control, active lane keeping, side-view assist, and lane departure warning systems following real-world use. Fifty-four Insurance Institute for Highway Safety employees participated and drove a 2016 Toyota Prius, 2016 Honda Civic, 2017 Audi Q7, or 2016 Infiniti QX60 for up to several weeks. Participants reported mileage and warnings from the technologies in an online daily-use survey. Participants reported their level of agreement with five statements regarding trust in an online post-use survey. Responses were averaged to create a composite measure of trust ranging from -2 (strongly disagree) to +2 (strongly agree) for each technology. Mixed-effect regression models were constructed to compare trust among technologies and separately among the study vehicles. Participants' free-response answers about what they liked least about each system were coded and examined. Participants reported driving 33,584 miles during 4 months of data collection. At least one forward collision warning was reported in 26% of the 354 daily reports. The proportion of daily reports indicating a forward collision warning was much larger for the Honda (70%) than for the Audi (18%), Infiniti (15%), and Toyota (10%). Trust was highest for side-view assist (0.98) and lowest for active lane keeping (0.20). Trust in side-view assist was significantly higher than trust in active lane keeping and lane departure warning (0.53). Trust in active lane keeping was significantly lower than trust in adaptive cruise control (0.67) and forward collision warning (0.71). Trust in adaptive cruise control was higher for the Audi (0.72) and Toyota (0.75) compared with the Honda (0.30), and significantly higher for the Infiniti (0.93). Trust in Infiniti's side-view assist (0.58) was significantly lower than trust in Audi (1.17) and Honda (1.23) systems. Coding of answers to free-response questions showed that more than 80% of complaints about Honda's adaptive cruise control were about the way it functioned and/or performed. Infiniti's side-view assist was the only one with complaints mentioning circumstances where it was used. Trust in forward collision warning, lane departure warning, and active lane keeping was not significantly different among vehicles. Driver trust varied among driver assistance technologies, and trust in adaptive cruise control and side-view assist differed among vehicles. Trust may affect real-world use of driver assistance technologies and limit the opportunity for the systems to provide their intended benefits.

  6. Habitat degradation and loss as key drivers of regional population extinction

    EPA Science Inventory

    Habitat quality is a fundamental driver of species distributions and population outcomes but is often difficult to measure. Further, habitat quality can be abstract, multi-faceted and challenging to compare alongside measures of habitat amount and fragmentation. Consequently, hab...

  7. The relationship of alcohol safety laws to drinking drivers in fatal crashes

    DOT National Transportation Integrated Search

    1999-08-01

    This paper presents an analysis of the relationships between the passage of key alcohol safety laws and the number of drinking drivers in fatal crashes. The study evaluated the impact of three major alcohol safety laws (administrative license revocat...

  8. Testing a structural model of young driver willingness to uptake Smartphone Driver Support Systems.

    PubMed

    Kervick, Aoife A; Hogan, Michael J; O'Hora, Denis; Sarma, Kiran M

    2015-10-01

    There is growing interest in the potential value of using phone applications that can monitor driver behaviour (Smartphone Driver Support Systems, 'SDSSs') in mitigating risky driving by young people. However, their value in this regard will only be realised if young people are willing to use this technology. This paper reports the findings of a study in which a novel structural model of willingness to use SDSSs was tested. Grounded in the driver monitoring and Technology Acceptance (TA) research literature, the model incorporates the perceived risks and gains associated with potential SDSS usage and additional social cognitive factors, including perceived usability and social influences. A total of 333 smartphone users, aged 18-24, with full Irish driving licenses completed an online questionnaire examining willingness or Behavioural Intention (BI) to uptake a SDSS. Following exploratory and confirmatory factor analyses, structural equation modelling indicated that perceived gains and social influence factors had significant direct effects on BI. Perceived risks and social influence also had significant indirect effects on BI, as mediated by perceived gains. Overall, this model accounted for 72.5% of the variance in willingness to uptake SDSSs. Multi-group structural models highlighted invariance of effects across gender, high and low risk drivers, and those likely or unlikely to adopt novel phone app technologies. These findings have implications for our understanding of the willingness of young drivers to adopt and use SDSSs, and highlight potential factors that could be targeted in behavioural change interventions seeking to improve usage rates. Copyright © 2015 Elsevier Ltd. All rights reserved.

  9. Revolution then evolution: the advance of health economic evaluation in Australia.

    PubMed

    Lopert, Ruth; Viney, Rosalie

    2014-01-01

    All governments face immense challenges in providing affordable healthcare for their citizens, and the diffusion of novel health technologies is a key driver of growth in expenditure for many. Although important methodological and process variations exist around the world, health economic evaluation is increasingly seen as an important tool to support decision-making around the introduction of new health technologies, interventions and programmes in countries of varying stages of economic development. In Australia, the assessment of the comparative cost-effectiveness of new medicines proposed for subsidy under the country's national drug subsidy programme, the Pharmaceutical Benefits Scheme, was introduced in the late 1980s and became mandatory in 1993, making Australia the first country to introduce such a requirement nationally. Since then the use of health economic evaluation has expanded and been applied to support decision-making across a broader range of health technologies, as well as to programmes in public health. Copyright © 2014. Published by Elsevier GmbH.

  10. Achieving success: assessing the role of and building a business case for technology in healthcare.

    PubMed

    Neumann, C L; Blouin, A S; Byrne, E M

    1999-01-01

    As the healthcare market continues to evolve, technology will play an increasingly important role in an integrated delivery system's ability to provide high-quality, cost-effective care. Healthcare leaders must be proactive and forward thinking about their technology investments. The financial investment for technology innovation can be significant. Therefore, it is important that healthcare executives deliberately design the role of technology and develop a consistent method for evaluating, identifying, and prioritizing technology investments. The article begins by describing technology's role in a healthcare organization as a window to the organization, a key driver of business strategy, and a high-performance enabler, and it develops a seven-step process for building a business case to ensure that an organization's technology investments are wise, well-reasoned, and will provide value to its customers. In addition, the article discusses the importance of combining people and process reengineering with new technology to exponentially increase the value to an organization. Healthcare leaders must understand the multiple roles of technology and consistently develop a business case when making technology investment decisions. Organizations driven by such an understanding will have a robust infrastructure of enabling technology designed to integrate people and process elements with technology to achieve the goals and initiatives of the organization. These organizations will lead the healthcare industry into the next millennium.

  11. Conference scene: Select Biosciences Epigenetics Europe 2010.

    PubMed

    Razvi, Enal S

    2011-02-01

    The field of epigenetics is now on a geometric rise, driven in a large part by the realization that modifiers of chromatin are key regulators of biological processes in vivo. The three major classes of epigenetic effectors are DNA methylation, histone post-translational modifications (such as acetylation, methylation or phosphorylation) and small noncoding RNAs (most notably microRNAs). In this article, I report from Select Biosciences Epigenetics Europe 2010 industry conference held on 14-15 September 2010 at The Burlington Hotel, Dublin, Ireland. This industry conference was extremely well attended with a global pool of delegates representing the academic research community, biotechnology companies and pharmaceutical companies, as well as the technology/tool developers. This conference represented the current state of the epigenetics community with cancer/oncology as a key driver. In fact, it has been estimated that approximately 45% of epigenetic researchers today identify cancer/oncology as their main area of focus vis-à-vis their epigenetic research efforts.

  12. Mars Design Reference Architecture 5.0 Study: Executive Summary

    NASA Technical Reports Server (NTRS)

    Drake, Bret G.

    2008-01-01

    The NASA Mars Design Reference Architecture 5.0 Study seeks to update its long term goals and objective for human exploration missions; flight and surface systems for human missions and supporting infrastructure; operational concept for human and robotic exploration of Mars; key challenges including risk and cost drivers; and, its development schedule options. It additionally seeks to assess strategic linkages between lunar and Mars strategies and develop and understanding of methods for reducing the cost/risk of human Mars missions through investment in research, technology development, and synergy with other exploration plans. Recommendations are made regarding conjunction class (long-stay) missions which are seen as providing the best balance of cost, risk, and performance. Additionally, this study reviews entry, descent, and landing challenges; in-space transportation systems; launch vehicle and Orion assessments; risk and risk mitigation; key driving requirements and challenges; and, lunar linkages.

  13. Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events

    PubMed Central

    Ashouri, Arghavan; Sayin, Volkan I.; Van den Eynden, Jimmy; Singh, Simranjit X.; Papagiannakopoulos, Thales; Larsson, Erik

    2016-01-01

    Thousands of long non-coding RNAs (lncRNAs) lie interspersed with coding genes across the genome, and a small subset has been implicated as downstream effectors in oncogenic pathways. Here we make use of transcriptome and exome sequencing data from thousands of tumours across 19 cancer types, to identify lncRNAs that are induced or repressed in relation to somatic mutations in key oncogenic driver genes. Our screen confirms known coding and non-coding effectors and also associates many new lncRNAs to relevant pathways. The associations are often highly reproducible across cancer types, and while many lncRNAs are co-expressed with their protein-coding hosts or neighbours, some are intergenic and independent. We highlight lncRNAs with possible functions downstream of the tumour suppressor TP53 and the master antioxidant transcription factor NFE2L2. Our study provides a comprehensive overview of lncRNA transcriptional alterations in relation to key driver mutational events in human cancers. PMID:28959951

  14. Unveiling the geography of historical patents in the United States from 1836 to 1975

    PubMed Central

    Petralia, Sergio; Balland, Pierre-Alexandre; Rigby, David L.

    2016-01-01

    It is clear that technology is a key driver of economic growth. Much less clear is where new technologies are produced and how the geography of U.S. invention has changed over the last two hundred years. Patent data report the geography, history, and technological characteristics of invention. However, those data have only recently become available in digital form and at the present time there exists no comprehensive dataset on the geography of knowledge production in the United States prior to 1975. The database presented in this paper unveils the geography of historical patents granted by the United States Patent and Trademark Office (USPTO) from 1836 to 1975. This historical dataset, HistPat, is constructed using digitalized records of original patent documents that are publicly available. We describe a methodological procedure that allows recovery of geographical information on patents from the digital records. HistPat can be used in different disciplines ranging from geography, economics, history, network science, and science and technology studies. Additionally, it is easily merged with post-1975 USPTO digital patent data to extend it until today. PMID:27576103

  15. Adolescent and adult drivers' mobile phone use while driving with different interlocutors.

    PubMed

    Mirman, Jessica H; Durbin, Dennis R; Lee, Yi-Ching; Seifert, Sara J

    2017-07-01

    We examined the frequency of adolescents' and their parents' mobile phone use while driving (MPUWD) in the context of their peer and parent-child interlocutors (i.e., communication partners), considering individual differences in perceived risk and symptoms of technology addiction. Ninety-four participants (47 parent-adolescent dyads) completed a survey battery measuring their symptoms of technology addiction, perceived risk of MPUWD, and MPUWD with family members and with their peers as assessed via the proportion of trips when drivers used a mobile phone to communicate. For both adolescents and their parents across both types of interlocutors (parent-child, peer), stronger risk perceptions were associated with less MPUWD, and stronger symptoms of technology addiction were associated with more MPUWD. A three-way interaction among technology addiction, interlocutor (parent-child, peer), and driver (parent, adolescent) was observed. For adolescents, the association between technology addiction and MPUWD was significantly stronger for MPUWD with their peers than it was for their MPUWD with their parents; this association was not observed for parents. Parents engaged in MPUWD with their children as frequently as adolescents engaged in MPUWD with their peers. Symptoms of technology addiction play a stronger role for adolescents' MPUWD with their peers than it does for adolescents' MPUWD with their parents. These and other driver-by-interlocutor interactions should be considered in future research on distracted driving and in prevention efforts. Copyright © 2017 Elsevier Ltd. All rights reserved.

  16. Modeling single event induced crosstalk in nanometer technologies

    NASA Astrophysics Data System (ADS)

    Boorla, Vijay K.

    Radiation effects become more important in combinational logic circuits with newer technologies. When a high energetic particle strikes at the sensitive region within the combinational logic circuit a voltage pulse called Single Event Transient is created. Recently, researchers reported Single Event Crosstalk because of increasing coupling effects. In this work, the closed form expression for SE crosstalk noise is formulated for the first time. For all calculations, 4-pi model is used in this work. The crosstalk model uses a reduced transfer function between aggressor coupling node and victim node to reduce information loss. Aggressor coupling node waveform is obtained and then applied to transfer function between the coupling node and the victim output to obtain victim noise voltage. This work includes both effect of passive aggressor loading on victim and victim loading on aggressor by considering resistive shielding effect. Noise peak expressions derived in this work show very good results in comparison to HSPICE results. Results show that average error for noise peak is 3.794% while allowing for very fast analysis. Once the SE crosstalk noise is calculated, one can hire mitigation techniques such as driver sizing. A standard DTMOS technique along with sizing is proposed in this work to mitigate SE crosstalk. This combined approach can saves in some areas compared to driver sizing alone. Key Words: Crosstalk Noise, Closed Form Modeling, Standard DTMOS

  17. Enhancing the Quantitative Representation of Socioeconomic Conditions in the Shared Socio-economic Pathways (SSPs) using the International Futures Model

    NASA Astrophysics Data System (ADS)

    Rothman, D. S.; Siraj, A.; Hughes, B.

    2013-12-01

    The international research community is currently in the process of developing new scenarios for climate change research. One component of these scenarios are the Shared Socio-economic Pathways (SSPs), which describe a set of possible future socioeconomic conditions. These are presented in narrative storylines with associated quantitative drivers. The core quantitative drivers include total population, average GDP per capita, educational attainment, and urbanization at the global, regional, and national levels. At the same time there have been calls, particularly by the IAV community, for the SSPs to include additional quantitative information on other key social factors, such as income inequality, governance, health, and access to key infrastructures, which are discussed in the narratives. The International Futures system (IFs), based at the Pardee Center at the University of Denver, is able to provide forecasts of many of these indicators. IFs cannot use the SSP drivers as exogenous inputs, but we are able to create development pathways that closely reproduce the core quantitative drivers defined by the different SSPs, as well as incorporating assumptions on other key driving factors described in the qualitative narratives. In this paper, we present forecasts for additional quantitative indicators based upon the implementation of the SSP development pathways in IFs. These results will be of value to many researchers.

  18. Understanding local-scale drivers of biodiversity outcomes in terrestrial protected areas.

    PubMed

    Barnes, Megan D; Craigie, Ian D; Dudley, Nigel; Hockings, Marc

    2017-07-01

    Conservation relies heavily on protected areas (PAs) maintaining their key biodiversity features to meet global biodiversity conservation goals. However, PAs have had variable success, with many failing to fully maintain their biodiversity features. The current literature concerning what drives variability in PA performance is rapidly expanding but unclear, sometimes contradictory, and spread across multiple disciplines. A clear understanding of the drivers of successful biodiversity conservation in PAs is necessary to make them fully effective. Here, we conduct a comprehensive assessment of the current state of knowledge concerning the drivers of biological outcomes within PAs, focusing on those that can be addressed at local scales. We evaluate evidence in support of potential drivers to identify those that enable more successful outcomes and those that impede success and provide a synthetic review. Interactions are discussed where they are known, and we highlight gaps in understanding. We find that elements of PA design, management, and local and national governance challenges, species and system ecology, and sociopolitical context can all influence outcomes. Adjusting PA management to focus on actions and policies that influence the key drivers identified here could improve global biodiversity outcomes. © 2016 New York Academy of Sciences.

  19. Volvo and Infiniti drivers' experiences with select crash avoidance technologies.

    PubMed

    Braitman, Keli A; McCartt, Anne T; Zuby, David S; Singer, Jeremiah

    2010-06-01

    Vehicle-based crash avoidance systems can potentially reduce crashes, but success depends on driver acceptance and understanding. This study gauged driver use, experience, and acceptance among early adopters of select technologies. Telephone interviews were conducted in early 2009 with 380 owners of Volvo vehicles equipped with forward collision warning with autobrake, lane departure warning, side-view assist, and/or active bi-xenon headlights and 485 owners of Infiniti vehicles with lane departure warning/prevention. Most owners kept systems turned on most of the time, especially forward collision warning with autobrake and side-view assist. The exception was lane departure prevention; many owners were unaware they had it, and the system must be activated each time the vehicle is started. Most owners reported being safer with the technologies and would want them again on their next vehicles. Perceived false or unnecessary warnings were fairly common, particularly with side-view assist. Some systems were annoying, especially lane departure warning. Many owners reported safer driving behaviors such as greater use of turn signals (lane departure warning), increased following distance (forward collision warning), and checking side mirrors more frequently (side-view assist), but some reported driving faster at night (active headlights). Despite some unnecessary or annoying warnings, most Volvo and Infiniti owners use crash avoidance systems most of the time. Among early adopters, the first requirement of effective warning systems (that owners use the technology) seems largely met. Systems requiring activation by drivers for each trip are used less often. Owner experience with the latest technologies from other automobile manufacturers should be studied, as well as for vehicles on which technologies are standard (versus optional) equipment. The effectiveness of technologies in preventing and mitigating crashes and injuries, and user acceptance of interfaces, should be examined as more vehicles with advanced technologies penetrate the fleet.

  20. Automatic Recognition and Understanding of the Driving Environment for Driver Feedback

    DOT National Transportation Integrated Search

    2018-01-01

    A smart driving system must consider two key elements to be able to generate recommendations and make driving decisions that are effective and accurate: The environment of the car and the behavior of the driver. Our long-term goal is to develop techn...

  1. Safety in numbers? Investigating Australian driver behaviour, knowledge and attitudes towards cyclists.

    PubMed

    Johnson, Marilyn; Oxley, Jennie; Newstead, Stuart; Charlton, Judith

    2014-09-01

    A key tenet of the safety in numbers theory is that as the number of people cycling increases, more drivers will also be cyclists and therefore will give greater consideration to cyclists when driving. We tested this theory in relation to self-reported behaviour, attitudes and knowledge in relation to cycling. An online survey was conducted of Australian drivers (n=1984) who were also cyclists (cyclist-drivers) and drivers who did not cycle (drivers). Cyclist-drivers were 1.5 times more likely than drivers to report safe driving behaviours related to sharing the roads with cyclists (95% CI: 1.1-1.9, p<0.01). Cyclist-drivers had better knowledge of the road rules related to cycling infrastructure than drivers; however knowledge of road rules related to bike lanes was low for both groups. Drivers were more likely than cyclist-drivers to have negative attitudes (e.g. cyclists are unpredictable and repeatedly overtaking cyclists is frustrating). Findings from this study highlight the need for increased education and awareness in relation to safe driving behaviour, road rules and attitudes towards cyclists. Specific recommendations are made for approaches to improve safety for cyclists. Copyright © 2014. Published by Elsevier Ltd.

  2. Multimission helicopter cockpit displays

    NASA Astrophysics Data System (ADS)

    Terry, William S.; Terry, Jody K.; Lovelace, Nancy D.

    1996-05-01

    A new operator display subsystem is being incorporated as part of the next generation United States Navy (USN) helicopter avionics system to be integrated into the multi-mission helicopter (MMH) that replaces both the SH-60B and the SH-60F in 2001. This subsystem exploits state-of-the-art technology for the display hardware, the display driver hardware, information presentation methodologies, and software architecture. Both of the existing SH-60 helicopter display systems are based on monochrome CRT technology; a key feature of the MMH cockpit is the integration of color AMLCD multifunction displays. The MMH program is one of the first military programs to use modified commercial AMLCD elements in a tactical aircraft. This paper presents the general configuration of the MMH cockpit and multifunction display subsystem and discusses the approach taken for presenting helicopter flight information to the pilots as well as presentation of mission sensor data for use by the copilot.

  3. BigData as a Driver for Capacity Building in Astrophysics

    NASA Astrophysics Data System (ADS)

    Shastri, Prajval

    2015-08-01

    Exciting public interest in astrophysics acquires new significance in the era of Big Data. Since Big Data involves advanced technologies of both software and hardware, astrophysics with Big Data has the potential to inspire young minds with diverse inclinations - i.e., not just those attracted to physics but also those pursuing engineering careers. Digital technologies have become steadily cheaper, which can enable expansion of the Big Data user pool considerably, especially to communities that may not yet be in the astrophysics mainstream, but have high potential because of access to thesetechnologies. For success, however, capacity building at the early stages becomes key. The development of on-line pedagogical resources in astrophysics, astrostatistics, data-mining and data visualisation that are designed around the big facilities of the future can be an important effort that drives such capacity building, especially if facilitated by the IAU.

  4. The Mercury Project: A High Average Power, Gas-Cooled Laser For Inertial Fusion Energy Development

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bayramian, A; Armstrong, P; Ault, E

    Hundred-joule, kilowatt-class lasers based on diode-pumped solid-state technologies, are being developed worldwide for laser-plasma interactions and as prototypes for fusion energy drivers. The goal of the Mercury Laser Project is to develop key technologies within an architectural framework that demonstrates basic building blocks for scaling to larger multi-kilojoule systems for inertial fusion energy (IFE) applications. Mercury has requirements that include: scalability to IFE beamlines, 10 Hz repetition rate, high efficiency, and 10{sup 9} shot reliability. The Mercury laser has operated continuously for several hours at 55 J and 10 Hz with fourteen 4 x 6 cm{sup 2} ytterbium doped strontiummore » fluoroapatite (Yb:S-FAP) amplifier slabs pumped by eight 100 kW diode arrays. The 1047 nm fundamental wavelength was converted to 523 nm at 160 W average power with 73% conversion efficiency using yttrium calcium oxy-borate (YCOB).« less

  5. Hybrid Electric Propulsion Technologies for Commercial Transports

    NASA Technical Reports Server (NTRS)

    Bowman, Cheryl; Jansen, Ralph; Jankovsky, Amy

    2016-01-01

    NASA Aeronautics Research Mission Directorate has set strategic research thrusts to address the major drivers of aviation such as growth in demand for high-speed mobility, addressing global climate and capitalizing in the convergence of technological advances. Transitioning aviation to low carbon propulsion is one of the key strategic research thrust and drives the search for alternative and greener propulsion system for advanced aircraft configurations. This work requires multidisciplinary skills coming from multiple entities. The Hybrid Gas-Electric Subproject in the Advanced Air Transportation Project is energizing the transport class landscape by accepting the technical challenge of identifying and validating a transport class aircraft with net benefit from hybrid propulsion. This highly integrated aircraft of the future will only happen if airframe expertise from NASA Langley, modeling and simulation expertise from NASA Ames, propulsion expertise from NASA Glenn, and the flight research capabilities from NASA Armstrong are brought together to leverage the rich capabilities of U.S. Industry and Academia.

  6. A Quality Function Deployment Method Applied to Highly Reusable Space Transportation

    NASA Technical Reports Server (NTRS)

    Zapata, Edgar

    2016-01-01

    This paper will describe a Quality Function Deployment (QFD) currently in work the goal of which is to add definition and insight to the development of long term Highly Reusable Space Transportation (HRST). The objective here is twofold. First, to describe the process, the actual QFD experience as applies to the HRST study. Second, to describe the preliminary results of this process, in particular the assessment of possible directions for future pursuit such as promising candidate technologies or approaches that may finally open the space frontier. The iterative and synergistic nature of QFD provides opportunities in the process for the discovery of what is key in so far as it is useful, what is not, and what is merely true. Key observations on the QFD process will be presented. The importance of a customer definition as well as the similarity of the process of developing a technology portfolio to product development will be shown. Also, the relation of identified cost and operating drivers to future space vehicle designs that are robust to an uncertain future will be discussed. The results in particular of this HRST evaluation will be preliminary given the somewhat long term (or perhaps not?) nature of the task being considered.

  7. Fisheye camera around view monitoring system

    NASA Astrophysics Data System (ADS)

    Feng, Cong; Ma, Xinjun; Li, Yuanyuan; Wu, Chenchen

    2018-04-01

    360 degree around view monitoring system is the key technology of the advanced driver assistance system, which is used to assist the driver to clear the blind area, and has high application value. In this paper, we study the transformation relationship between multi coordinate system to generate panoramic image in the unified car coordinate system. Firstly, the panoramic image is divided into four regions. By using the parameters obtained by calibration, four fisheye images pixel corresponding to the four sub regions are mapped to the constructed panoramic image. On the basis of 2D around view monitoring system, 3D version is realized by reconstructing the projection surface. Then, we compare 2D around view scheme and 3D around view scheme in unified coordinate system, 3D around view scheme solves the shortcomings of the traditional 2D scheme, such as small visual field, prominent ground object deformation and so on. Finally, the image collected by a fisheye camera installed around the car body can be spliced into a 360 degree panoramic image. So it has very high application value.

  8. Automotive HMI design and participatory user involvement: review and perspectives.

    PubMed

    François, Mathilde; Osiurak, François; Fort, Alexandra; Crave, Philippe; Navarro, Jordan

    2017-04-01

    Automotive human-machine interface (HMI) design is facing new challenges due to the technological advances of the last decades. The design process has to be adapted in order to address human factors and road safety challenges. It is now widely accepted that user involvement in the HMI design process is valuable. However, the current form of user involvement in industry remains at the stages of concept assessment and usability tests. Moreover, the literature in other fields (e.g. information systems) promotes a broader user involvement with participatory design (i.e. the user is fully involved in the development process). This article reviews the established benefits of participatory design and reveals perspectives for automotive HMI quality improvement in a cognitive ergonomic framework. Practitioner Summary: Automotive HMI quality determines, in part, drivers' ability to perform primary driving tasks while using in-vehicle devices. User involvement in the design process is a key point to contribute to HMI quality. This article reports the potential benefits of a broad involvement from drivers to meet automotive HMI design challenges.

  9. Water footprint scenarios for 2050: a global analysis.

    PubMed

    Ercin, A Ertug; Hoekstra, Arjen Y

    2014-03-01

    This study develops water footprint scenarios for 2050 based on a number of drivers of change: population growth, economic growth, production/trade pattern, consumption pattern (dietary change, bioenergy use) and technological development. The objective the study is to understand the changes in the water footprint (WF) of production and consumption for possible futures by region and to elaborate the main drivers of this change. In addition, we assess virtual water flows between the regions of the world to show dependencies of regions on water resources in other regions under different possible futures. We constructed four scenarios, along two axes, representing two key dimensions of uncertainty: globalization versus regional selfsufficiency, and economy-driven development versus development driven by social and environmental objectives. The study shows how different drivers will change the level of water consumption and pollution globally in 2050. The presented scenarios can form a basis for a further assessment of how humanity can mitigate future freshwater scarcity. We showed with this study that reducing humanity's water footprint to sustainable levels is possible even with increasing populations, provided that consumption patterns change. This study can help to guide corrective policies at both national and international levels, and to set priorities for the years ahead in order to achieve sustainable and equitable use of the world's fresh water resources. Copyright © 2013 Elsevier Ltd. All rights reserved.

  10. Design of robotic leg and physiotherapy (ROLEP) assist with interactive game

    NASA Astrophysics Data System (ADS)

    Hasan, A. F.; Husin, M. F. Che; Hashim, M. N.; Rosli, K. A.; Roslim, F. R. A.; Abidin, A. F. Z.

    2017-09-01

    Injuries in certain parts of the feet can cause a person to have difficulty in walking or running if it is not treated through physiotherapy. In Malaysia, therapy centers only provide a service or the use of basic tools that are not efficient as more sophisticated equipment requires a high cost. In fact, exercise requiring close monitoring physiotherapist are also at a high cost. Therefore, using robot therapy is a new technology that can provide an alternative way to solve this problem. The implementation of this project has produced a robotic physiotherapy which has one degree of freedom, portable and inexpensive way to help the movement of the patient's leg. It covers basic electrical circuits, mechanical components, programming and has been combined with an interactive game as the main driver. ROLEP (Robotic-Leg-Physiotherapy) is able to help patients through the therapy process. It was built using CT-UNO as its microprocessor connected to MD10-C which acted as the motor driver. The interactive game produced by using Unity game software is a key driver in getting rid of boredom and reduce pain. As a result, ROLEP designed can operate well within its range of the patient's weight. It has the advantage of portability and easy to use by the patients. ROLEP expected to help patients undergoing therapy process more efficient and interesting in the process of recovery.

  11. Scenarios use to engage scientists and decision-makers in a changing Arctic

    NASA Astrophysics Data System (ADS)

    Lee, O. A.; Eicken, H.; Payne, J. F.

    2015-12-01

    Scenarios provide a framework to develop more adaptive Arctic policies that allow decision makers to consider the best available science to address complex relationships and key uncertainties in drivers of change. These drivers may encompass biophysical factors such as climate change, socioeconomic drivers, and wild-cards that represent low likelihood but influential events such as major environmental disasters. We outline some of the lessons learned from the North Slope Science Initiative (NSSI) scenarios project that could help in the development of adaptive science-based policies. Three spatially explicit development scenarios were identified corresponding to low, medium and high resource extraction activities on the North Slope and adjacent seas. In the case of the high energy development scenario science needs were focused on new technology, oil spill response, and the effects of offshore activities on marine mammals important for subsistence. Science needs related to community culture, erosion, permafrost degradation and hunting and trapping on land were also identified for all three scenarios. The NSSI science needs will guide recommendations for future observing efforts, and data from these observing activities could subsequently improve policy guidance for emergency response, subsistence management and other issues. Scenarios at pan-Arctic scales may help improve the development of international policies for resilient northern communities and encourage the use of science to reduce uncertainties in plans for adapting to change in the Arctic.

  12. Mine countermeasures (MCM) sensor technology drivers

    NASA Astrophysics Data System (ADS)

    Skinner, David P.

    1995-06-01

    In recent years, MCM has moved to the forefront of the Navy's attention. This paper describes the general problems that drive the technology requirements of classical sea mine countermeasure (MCM) sensors for those working outside of this specialized area. Sensor requirements for MCM are compared with those for antisubmarine warfare. This highlights the unique environmental issues and crucial false target problems. The elimination of false targets, not mine detection, is the principal driver of MCM sensor requirements and places special emphasis on the technologies needed for the sequential operations of detection, classification, and identification.

  13. Disruptive laser diode source for embedded LIDAR sensors

    NASA Astrophysics Data System (ADS)

    Canal, Celine; Laugustin, Arnaud; Kohl, Andreas; Rabot, Olivier

    2017-02-01

    Active imaging based on laser illumination is used in various fields such as medicine, security, defense, civil engineering and in the automotive sector. In this last domain, research and development to bring autonomous vehicles on the roads has been intensified these last years with an emphasis on lidar technology that is probably the key to achieve full automation level. Based on time-of-flight measurements, the profile of objects can be measured together with their location in various conditions, creating a 3D mapping of the environment. To be embedded on a vehicle as advanced driver assistance systems (ADAS), these sensors require compactness, low-cost and reliability, as it is provided by a flash lidar. An attractive candidate, especially with respect to cost reduction, for the laser source integrated in these devices is certainly laser diodes as long as they can provide sufficiently short pulses with a high energy. A recent breakthrough in laser diode and diode driver technology made by Quantel (Les Ulis, France) now allows laser emission higher than 1 mJ with pulses as short as 12 ns in a footprint of 4x5 cm2 (including both the laser diode and driver) and an electrical-to-optical conversion efficiency of the whole laser diode source higher than 25% at this level of energy. The components used for the laser source presented here can all be manufactured at low cost. In particular, instead of having several individual laser diodes positioned side by side, the laser diodes are monolithically integrated on a single semiconductor chip. The chips are then integrated directly on the driver board in a single assembly step. These laser sources emit in the range of 800-1000 nm and their emission is considered to be eye safe when taking into account the high divergence of the output beam and the aperture of possible macro lenses so that they can be used for end consumer applications. Experimental characterization of these state-of-the-art pulsed laser diode sources will be given. Future work leads will be discussed for miniaturization of the laser diode and drastic cost reduction.

  14. Structures and Materials Working Group report

    NASA Technical Reports Server (NTRS)

    Torczyner, Robert; Hanks, Brantley R.

    1986-01-01

    The appropriateness of the selection of four issues (advanced materials development, analysis/design methods, tests of large flexible structures, and structural concepts) was evaluated. A cross-check of the issues and their relationship to the technology drivers is presented. Although all of the issues addressed numerous drivers, the advanced materials development issue impacts six out of the seven drivers and is considered to be the most crucial. The advanced materials technology development and the advanced design/analysis methods development were determined to be enabling technologies with the testing issues and development of structural concepts considered to be of great importance, although not enabling technologies. In addition, and of more general interest and criticality, the need for a Government/Industry commitment which does not now exist, was established. This commitment would call for the establishment of the required infrastructure to facilitate the development of the capabilities highlighted through the availability of resources and testbed facilities, including a national testbed in space to be in place in ten years.

  15. Driver Distraction with Wireless Telecommunications and Route Guidance Systems

    DOT National Transportation Integrated Search

    2000-07-01

    Concerns have been raised in recent years about the distraction potential of Intelligent Transportation Systems (ITS) technologies including driver : information systems such as route navigation systems. The research described in this report had the ...

  16. Driving safely into the future with applied technology

    DOT National Transportation Integrated Search

    1999-10-01

    Driver error remains the leading cause of highway crashes. Through the Intelligent Vehicle Initiative (IVI), the Department of Transportation hopes to reduce crashes by helping drivers avoid hazardous mistakes. IVI aims to accelerate the development ...

  17. Internet driver education study.

    DOT National Transportation Integrated Search

    2010-05-01

    Incorporating technology through online courses, including drivers education (DE), is the wave of the future for : learning. While many states allow online DE as an accepted method of learning, Wisconsin currently only allows it on a : limited bas...

  18. Threshold wind velocity dynamics as a driver of aeolian sediment mas flux

    USDA-ARS?s Scientific Manuscript database

    Horizontal (saltation) mass flux is a key driver of aeolian dust emission. Estimates of the horizontal mass flux underpin assessments of the global dust budget and influence our understanding of the dust cycle and its interactions. Current equations for predicting horizontal mass flux are based on l...

  19. Drunk Driver Testing

    NASA Technical Reports Server (NTRS)

    1984-01-01

    Systems Technology, Inc. developed a technique to study/measure behavioral changes brought on by long term isolation is now being used in a system for determining whether a driver is too drunk to drive. Device is intended to discourage intoxicated drivers from taking to the road by advising them they are in no condition to operate a vehicle. System is being tested experimentally in California.

  20. TMEM88, CCL14 and CLEC3B as prognostic biomarkers for prognosis and palindromia of human hepatocellular carcinoma.

    PubMed

    Zhang, Xin; Wan, Jin-Xiang; Ke, Zun-Ping; Wang, Feng; Chai, Hai-Xia; Liu, Jia-Qiang

    2017-07-01

    Hepatocellular carcinoma is one of the most mortal and prevalent cancers with increasing incidence worldwide. Elucidating genetic driver genes for prognosis and palindromia of hepatocellular carcinoma helps managing clinical decisions for patients. In this study, the high-throughput RNA sequencing data on platform IlluminaHiSeq of hepatocellular carcinoma were downloaded from The Cancer Genome Atlas with 330 primary hepatocellular carcinoma patient samples. Stable key genes with differential expressions were identified with which Kaplan-Meier survival analysis was performed using Cox proportional hazards test in R language. Driver genes influencing the prognosis of this disease were determined using clustering analysis. Functional analysis of driver genes was performed by literature search and Gene Set Enrichment Analysis. Finally, the selected driver genes were verified using external dataset GSE40873. A total of 5781 stable key genes were identified, including 156 genes definitely related to prognoses of hepatocellular carcinoma. Based on the significant key genes, samples were grouped into five clusters which were further integrated into high- and low-risk classes based on clinical features. TMEM88, CCL14, and CLEC3B were selected as driver genes which clustered high-/low-risk patients successfully (generally, p = 0.0005124445). Finally, survival analysis of the high-/low-risk samples from external database illustrated significant difference with p value 0.0198. In conclusion, TMEM88, CCL14, and CLEC3B genes were stable and available in predicting the survival and palindromia time of hepatocellular carcinoma. These genes could function as potential prognostic genes contributing to improve patients' outcomes and survival.

  1. White biotechnology: State of the art strategies for the development of biocatalysts for biorefining.

    PubMed

    Heux, S; Meynial-Salles, I; O'Donohue, M J; Dumon, C

    2015-12-01

    White biotechnology is a term that is now often used to describe the implementation of biotechnology in the industrial sphere. Biocatalysts (enzymes and microorganisms) are the key tools of white biotechnology, which is considered to be one of the key technological drivers for the growing bioeconomy. Biocatalysts are already present in sectors such as the chemical and agro-food industries, and are used to manufacture products as diverse as antibiotics, paper pulp, bread or advanced polymers. This review proposes an original and global overview of highly complementary fields of biotechnology at both enzyme and microorganism level. A certain number of state of the art approaches that are now being used to improve the industrial fitness of biocatalysts particularly focused on the biorefinery sector are presented. The first part deals with the technologies that underpin the development of industrial biocatalysts, notably the discovery of new enzymes and enzyme improvement using directed evolution techniques. The second part describes the toolbox available by the cell engineer to shape the metabolism of microorganisms. And finally the last part focuses on the 'omic' technologies that are vital for understanding and guide microbial engineering toward more efficient microbial biocatalysts. Altogether, these techniques and strategies will undoubtedly help to achieve the challenging task of developing consolidated bioprocessing (i.e. CBP) readily available for industrial purpose. Copyright © 2015 Elsevier Inc. All rights reserved.

  2. Characterization of potential driver mutations involved in human breast cancer by computational approaches

    PubMed Central

    Rajendran, Barani Kumar; Deng, Chu-Xia

    2017-01-01

    Breast cancer is the second most frequently occurring form of cancer and is also the second most lethal cancer in women worldwide. A genetic mutation is one of the key factors that alter multiple cellular regulatory pathways and drive breast cancer initiation and progression yet nature of these cancer drivers remains elusive. In this article, we have reviewed various computational perspectives and algorithms for exploring breast cancer driver mutation genes. Using both frequency based and mutational exclusivity based approaches, we identified 195 driver genes and shortlisted 63 of them as candidate drivers for breast cancer using various computational approaches. Finally, we conducted network and pathway analysis to explore their functions in breast tumorigenesis including tumor initiation, progression, and metastasis. PMID:28477017

  3. Occupational therapists lead a national injury prevention strategy to help older drivers.

    PubMed

    Craik, Janet M

    2011-04-01

    As older adults are the fastest growing segment of the driving population, the Canadian Association of Occupational Therapists (CAOT) has taken older driver safety as a key priority. The purpose of this paper is to present the National Blueprint for Injury Prevention in Older Drivers (Blueprint) and its related activities. Since 2006, CAOT has been working on initiatives relating to the National Blueprint for Injury Prevention in Older Drivers. The most recent activities include the launch of informational brochures and a website. The Blueprint and its related activities were developed with the intent to prolong safe driving among older adults in Canada, and to propose future actions to be addressed by all stakeholders interested in older driver safety.

  4. Heavy vehicle driver workload assessment : executive summary

    DOT National Transportation Integrated Search

    1996-10-01

    This report summarizes a program of research to develop methods, data, and guidelines to conduct heavy vehicle driver-oriented workload assessments of new, high-technology, in-cab devices. Many such devices are being developed and implemented in heav...

  5. Feasibility Study for Electronic Fitness for Duty Medical Examination Reporting and Oversight.

    DOT National Transportation Integrated Search

    2016-11-01

    This report examines the institutional and high-level technology aspects associated with potential mandated : electronic reporting of every commercial driver license (CDL) driver fitness-for-duty medical examination : performed by a medical examiner ...

  6. Machine learning methods for locating re-entrant drivers from electrograms in a model of atrial fibrillation

    NASA Astrophysics Data System (ADS)

    McGillivray, Max Falkenberg; Cheng, William; Peters, Nicholas S.; Christensen, Kim

    2018-04-01

    Mapping resolution has recently been identified as a key limitation in successfully locating the drivers of atrial fibrillation (AF). Using a simple cellular automata model of AF, we demonstrate a method by which re-entrant drivers can be located quickly and accurately using a collection of indirect electrogram measurements. The method proposed employs simple, out-of-the-box machine learning algorithms to correlate characteristic electrogram gradients with the displacement of an electrogram recording from a re-entrant driver. Such a method is less sensitive to local fluctuations in electrical activity. As a result, the method successfully locates 95.4% of drivers in tissues containing a single driver, and 95.1% (92.6%) for the first (second) driver in tissues containing two drivers of AF. Additionally, we demonstrate how the technique can be applied to tissues with an arbitrary number of drivers. In its current form, the techniques presented are not refined enough for a clinical setting. However, the methods proposed offer a promising path for future investigations aimed at improving targeted ablation for AF.

  7. The drivers to adopt renewable energy among residential users.

    NASA Astrophysics Data System (ADS)

    Rahman, Zahari Abdul; Elinda, Esa

    2016-03-01

    This study aims to examine the drivers to adopt renewable energy (RE) among residential users in Malaysia. Based on the theoretical framework of a consumer’s decision making process, an empirical study of the adoption of RE was conducted. A total of 501 residential users were used in this study. This study proved that perceived utility of new technology, perceived utility of new service, and perceived benefit of new technology are the drivers to adopt RE among residential users. These factors are knowing crucial to RE suppliers and producers because it will generates more demand from the residential users and the percentage of energy mix from RE sources can be increase.

  8. Resolving key drivers of variability through an important circulation choke point in the western Mediterranean Sea; using gliders, models & satellite remote sensing

    NASA Astrophysics Data System (ADS)

    Heslop, Emma; Aguiar, Eva; Mourre, Baptiste; Juza, Mélanie; Escudier, Romain; Tintoré, Joaquín

    2017-04-01

    The Ibiza Channel plays an important role in the circulation of the Western Mediterranean Sea, it governs the north/south exchange of different water masses that are known to affect regional ecosystems and is influenced by variability in the different drivers that affect sub-basins to the north (N) and south (S). A complex system. In this study we use a multi-platform approach to resolve the key drivers of this variability, and gain insight into the inter-connection between the N and S of the Western Mediterranean Sea through this choke point. The 6-year glider time series from the quasi-continuous glider endurance line monitoring of the Ibiza Channel, undertaken by SOCIB (Balearic Coastal Ocean observing and Forecasting System), is used as the base from which to identify key sub-seasonal to inter-annual patterns and shifts in water mass properties and transport volumes. The glider data indicates the following key components in the variability of the N/S flow of different water mass through the channel; regional winter mode water production, change in intermediate water mass properties, northward flows of a fresher water mass and the basin-scale circulation. To resolve the drivers of these components of variability, the strength of combining datasets from different sources, glider, modeling, altimetry and moorings, is harnessed. To the north atmospheric forcing in the Gulf of Lions is a dominant driver, while to the south the mesoscale circulation patterns of the Atlantic Jet and Alboran gyres dominate the variability but do not appear to influence the fresher inflows. Evidence of a connection between the northern and southern sub-basins is however indicated. The study highlights importance of sub-seasonal variability and the scale of rapid change possible in the Mediterranean, as well as the benefits of leveraging high resolution glider datasets within a multi-platform and modelling study.

  9. Energy and Environmental Drivers of Stress and Conflict in Multi scale Models of Human Social Behavior

    DTIC Science & Technology

    2017-10-31

    Report: Energy and Environmental Drivers of Stress and Conflict in Multi-scale Models of Human Social Behavior The views, opinions and/or findings...RPPR Final Report as of 08-Feb-2018 Agreement Number: W911NF-12-1-0097 Organization: Santa Fe Institute of Science Title: Energy and...Article Title: Determinants of the Pace of Global Innovation in Energy Technologies Keywords: climage change, innovations in energy technologies

  10. Using driving simulators to assess driving safety.

    PubMed

    Boyle, Linda Ng; Lee, John D

    2010-05-01

    Changes in drivers, vehicles, and roadways pose substantial challenges to the transportation safety community. Crash records and naturalistic driving data are useful for examining the influence of past or existing technology on drivers, and the associations between risk factors and crashes. However, they are limited because causation cannot be established and technology not yet installed in production vehicles cannot be assessed. Driving simulators have become an increasingly widespread tool to understand evolving and novel technologies. The ability to manipulate independent variables in a randomized, controlled setting also provides the added benefit of identifying causal links. This paper introduces a special issue on simulator-based safety studies. The special issue comprises 25 papers that demonstrate the use of driving simulators to address pressing transportation safety problems and includes topics as diverse as neurological dysfunction, work zone design, and driver distraction. Copyright (c) 2010 Elsevier Ltd. All rights reserved.

  11. Thoracic, Lumbar, and Sacral Pedicle Screw Placement Using Stryker-Ziehm Virtual Screw Technology and Navigated Stryker Cordless Driver 3: Technical Note.

    PubMed

    Satarasinghe, Praveen; Hamilton, Kojo D; Tarver, Michael J; Buchanan, Robert J; Koltz, Michael T

    2018-04-17

    Utilization of pedicle screws (PS) for spine stabilization is common in spinal surgery. With reliance on visual inspection of anatomical landmarks prior to screw placement, the free-hand technique requires a high level of surgeon skill and precision. Three-dimensional (3D), computer-assisted virtual neuronavigation improves the precision of PS placement and minimization steps. Twenty-three patients with degenerative, traumatic, or neoplastic pathologies received treatment via a novel three-step PS technique that utilizes a navigated power driver in combination with virtual screw technology. (1) Following visualization of neuroanatomy using intraoperative CT, a navigated 3-mm match stick drill bit was inserted at an anatomical entry point with a screen projection showing a virtual screw. (2) A Navigated Stryker Cordless Driver with an appropriate tap was used to access the vertebral body through a pedicle with a screen projection again showing a virtual screw. (3) A Navigated Stryker Cordless Driver with an actual screw was used with a screen projection showing the same virtual screw. One hundred and forty-four consecutive screws were inserted using this three-step, navigated driver, virtual screw technique. Only 1 screw needed intraoperative revision after insertion using the three-step, navigated driver, virtual PS technique. This amounts to a 0.69% revision rate. One hundred percent of patients had intraoperative CT reconstructed images taken to confirm hardware placement. Pedicle screw placement utilizing the Stryker-Ziehm neuronavigation virtual screw technology with a three step, navigated power drill technique is safe and effective.

  12. Draft evidence report : traumatic brain injury and commercial motor vehicle driver safety (comprehensive review).

    DOT National Transportation Integrated Search

    2009-03-30

    Purpose of this evidence report is to address several key questions posed by the Federal Motor Carrier Safety Administration : Key question 1: What is the impact of traumatic brain injury on crash risk/driving performance? Key question 2: What factor...

  13. Research data management and libraries: relationships, activities, drivers and influences.

    PubMed

    Pinfield, Stephen; Cox, Andrew M; Smith, Jen

    2014-01-01

    The management of research data is now a major challenge for research organisations. Vast quantities of born-digital data are being produced in a wide variety of forms at a rapid rate in universities. This paper analyses the contribution of academic libraries to research data management (RDM) in the wider institutional context. In particular it: examines the roles and relationships involved in RDM, identifies the main components of an RDM programme, evaluates the major drivers for RDM activities, and analyses the key factors influencing the shape of RDM developments. The study is written from the perspective of library professionals, analysing data from 26 semi-structured interviews of library staff from different UK institutions. This is an early qualitative contribution to the topic complementing existing quantitative and case study approaches. Results show that although libraries are playing a significant role in RDM, there is uncertainty and variation in the relationship with other stakeholders such as IT services and research support offices. Current emphases in RDM programmes are on developments of policies and guidelines, with some early work on technology infrastructures and support services. Drivers for developments include storage, security, quality, compliance, preservation, and sharing with libraries associated most closely with the last three. The paper also highlights a 'jurisdictional' driver in which libraries are claiming a role in this space. A wide range of factors, including governance, resourcing and skills, are identified as influencing ongoing developments. From the analysis, a model is constructed designed to capture the main aspects of an institutional RDM programme. This model helps to clarify the different issues involved in RDM, identifying layers of activity, multiple stakeholders and drivers, and a large number of factors influencing the implementation of any initiative. Institutions may usefully benchmark their activities against the data and model in order to inform ongoing RDM activity.

  14. Research Data Management and Libraries: Relationships, Activities, Drivers and Influences

    PubMed Central

    Pinfield, Stephen; Cox, Andrew M.; Smith, Jen

    2014-01-01

    The management of research data is now a major challenge for research organisations. Vast quantities of born-digital data are being produced in a wide variety of forms at a rapid rate in universities. This paper analyses the contribution of academic libraries to research data management (RDM) in the wider institutional context. In particular it: examines the roles and relationships involved in RDM, identifies the main components of an RDM programme, evaluates the major drivers for RDM activities, and analyses the key factors influencing the shape of RDM developments. The study is written from the perspective of library professionals, analysing data from 26 semi-structured interviews of library staff from different UK institutions. This is an early qualitative contribution to the topic complementing existing quantitative and case study approaches. Results show that although libraries are playing a significant role in RDM, there is uncertainty and variation in the relationship with other stakeholders such as IT services and research support offices. Current emphases in RDM programmes are on developments of policies and guidelines, with some early work on technology infrastructures and support services. Drivers for developments include storage, security, quality, compliance, preservation, and sharing with libraries associated most closely with the last three. The paper also highlights a ‘jurisdictional’ driver in which libraries are claiming a role in this space. A wide range of factors, including governance, resourcing and skills, are identified as influencing ongoing developments. From the analysis, a model is constructed designed to capture the main aspects of an institutional RDM programme. This model helps to clarify the different issues involved in RDM, identifying layers of activity, multiple stakeholders and drivers, and a large number of factors influencing the implementation of any initiative. Institutions may usefully benchmark their activities against the data and model in order to inform ongoing RDM activity. PMID:25485539

  15. Medical review licensing outcomes in drivers with visual field loss in Victoria, Australia

    PubMed Central

    Muir, Carlyn; Charlton, Judith L; Odell, Morris; Keeffe, Jill; Wood, Joanne; Bohensky, Megan; Fildes, Brian; Oxley, Jennifer; Bentley, Sharon; Rizzo, Matthew

    2017-01-01

    Background Good vision is essential for safe driving and studies have associated visual impairment with an increased crash risk. Currently, there is little information about the medical review of drivers with visual field loss. This study examines the prevalence of visual field loss among drivers referred for medical review in one Australian jurisdiction and investigates factors associated with licence outcome in this group. Methods A random sample of 10,000 (31.25 per cent) medical review cases was extracted for analysis from the Victorian licensing authority. Files were screened for the presence of six visual field-related medical conditions. Data were captured on a range of variables, including referral source, age, gender, health status, crash history and licence outcome. Prevalence analyses were univariate and descriptive. Logistic regression was used to assess factors associated with licence outcomes in the visual field loss group. Results Approximately 1.9 per cent of the 10,000 medical review cases screened had a visual field loss condition identified (n=194). Among the visual field loss group, 57.2 per cent were permitted to continue driving (conditional/unconditional licence). Primary referral sources were the police, self-referrals and general medical practitioners. Key factors associated with licence test outcomes were visual field condition, age group, crash involvement and referral to the Driver Licensing Authority’s Medical Advisors. Those who were younger had a crash involvement triggering referral and those who were referred to the Medical Advisors were more likely to have a positive licensing outcome. Conclusion The evidence base for making licensing decisions is complicated by the variable causes, patterns, progressions and measuring technologies for visual field loss. This study highlighted that the involvement of an expert medical advisory service in Victoria resulted in an increased likelihood that drivers with visual field loss will be allowed to continue driving. Further research is warranted to explore issues relating to severity of field loss and the capacity for compensation. PMID:27530283

  16. Guidelines and Recommendations to Accommodate Older Drivers and Pedestrians

    DOT National Transportation Integrated Search

    2001-05-01

    This project updated, revised, and expanded the scope of the "Older Driver Highway Design Handbook" published by the Federal Highway Administration (FHWA) in 1998. Development of the updated Handbook (FHWA-RD-01-103) was complemented by a technology ...

  17. Guidelines and Recommendations to Accommodate Older Drivers and Pedestrians

    DOT National Transportation Integrated Search

    2001-10-01

    This project updated, revised, and expanded the scope of the "Older Driver Highway Design Handbook" published by the Federal Highway Administration (FHWA) in 1998. Development of the updated Handbook (FHWA-RD-01-103) was complemented by a technology ...

  18. Motivations for speeding : additional data analysis : traffic tech : technology transfer series.

    DOT National Transportation Integrated Search

    2016-03-01

    NHTSAs naturalistic driving study, Motivations for Speeding (Richard et al., 2013), examined motivations and situations conducive to speeding behavior. The study collected data from 88 drivers in Seattle, Washington, and 76 drivers in College Stat...

  19. Proving autonomous vehicle and advanced driver assistance systems safety : final research report.

    DOT National Transportation Integrated Search

    2016-02-15

    The main objective of this project was to provide technology for answering : crucial safety and correctness questions about verification of autonomous : vehicle and advanced driver assistance systems based on logic. : In synergistic activities, we ha...

  20. Secure and private sensing for driver authentication and transportation safety : final report.

    DOT National Transportation Integrated Search

    2017-08-01

    Recent technology trends have allowed affordable and efficient collection of driver data. This has enabled a variety of potential applications, including more accurate pricing determinations for insurance and finer grained traffic planning for improv...

  1. Medication adherence in schizophrenia: factors influencing adherence and consequences of nonadherence, a systematic literature review

    PubMed Central

    Medic, Goran; Littlewood, Kavi J.; Diez, Teresa; Granström, Ola; De Hert, Marc

    2013-01-01

    Background: Nonadherence to medication is a recognized problem and may be the most challenging aspect of treatment. Methods: We performed a systematic review of factors that influence adherence and the consequences of nonadherence to the patient, healthcare system and society, in patients with schizophrenia. Particular attention was given to the effect of nonadherence on hospitalization rates, as a key driver of increased costs of care. A qualitative systematic literature review was conducted using a broad search strategy using disease and adherence terms. Due to the large number of abstracts identified, article selection was based on studies with larger sample sizes published after 2001. Thirty-seven full papers were included: 15 studies on drivers and 22 on consequences, of which 12 assessed the link between nonadherence and hospitalization. Results: Key drivers of nonadherence included lack of insight, medication beliefs and substance abuse. Key consequences of nonadherence included greater risk of relapse, hospitalization and suicide. Factors positively related to adherence were a good therapeutic relationship with physician and perception of benefits of medication. The most frequently reported driver and consequence were lack of insight and greater risk of hospitalization respectively. Conclusions: Improving adherence in schizophrenia may have a considerable positive impact on patients and society. This can be achieved by focusing on the identified multitude of factors driving nonadherence. PMID:24167693

  2. Comprehensive analysis of transcriptome variation uncovers known and novel driver events in T-cell acute lymphoblastic leukemia.

    PubMed

    Atak, Zeynep Kalender; Gianfelici, Valentina; Hulselmans, Gert; De Keersmaecker, Kim; Devasia, Arun George; Geerdens, Ellen; Mentens, Nicole; Chiaretti, Sabina; Durinck, Kaat; Uyttebroeck, Anne; Vandenberghe, Peter; Wlodarska, Iwona; Cloos, Jacqueline; Foà, Robin; Speleman, Frank; Cools, Jan; Aerts, Stein

    2013-01-01

    RNA-seq is a promising technology to re-sequence protein coding genes for the identification of single nucleotide variants (SNV), while simultaneously obtaining information on structural variations and gene expression perturbations. We asked whether RNA-seq is suitable for the detection of driver mutations in T-cell acute lymphoblastic leukemia (T-ALL). These leukemias are caused by a combination of gene fusions, over-expression of transcription factors and cooperative point mutations in oncogenes and tumor suppressor genes. We analyzed 31 T-ALL patient samples and 18 T-ALL cell lines by high-coverage paired-end RNA-seq. First, we optimized the detection of SNVs in RNA-seq data by comparing the results with exome re-sequencing data. We identified known driver genes with recurrent protein altering variations, as well as several new candidates including H3F3A, PTK2B, and STAT5B. Next, we determined accurate gene expression levels from the RNA-seq data through normalizations and batch effect removal, and used these to classify patients into T-ALL subtypes. Finally, we detected gene fusions, of which several can explain the over-expression of key driver genes such as TLX1, PLAG1, LMO1, or NKX2-1; and others result in novel fusion transcripts encoding activated kinases (SSBP2-FER and TPM3-JAK2) or involving MLLT10. In conclusion, we present novel analysis pipelines for variant calling, variant filtering, and expression normalization on RNA-seq data, and successfully applied these for the detection of translocations, point mutations, INDELs, exon-skipping events, and expression perturbations in T-ALL.

  3. Commercial Motor Vehicle Driver Obstructive Sleep Apnea Screening and Treatment in the United States: An Update and Recommendation Overview

    PubMed Central

    Colvin, Loretta J.; Collop, Nancy A.

    2016-01-01

    No regulatory mandate exists in the United States (U.S.) for comprehensive obstructive sleep apnea (OSA) risk assessment and stratification for commercial motor vehicle (CMV) drivers. Current Federal Motor Carrier Safety Administration (FMCSA) requirements are outdated and depend largely on subjective report, a less reliable strategy in an occupational setting. Without FMCSA standards, sleep specialists, occupational medical examiners and employers rely on a collection of medical consensus recommendations to establish standards of care. These recommendations advise OSA risk assessment through a combination of focused medical history, physical examination, questionnaires, and accident history, which increase OSA detection compared to current FMCSA standards. For those diagnosed with OSA, consensus-based risk stratification helps identify CMV drivers who may benefit from OSA treatment and establish minimum standards for assessing treatment efficacy and adherence. Unfortunately no consolidated recommendation exists; rather, publications span medical and governmental literature in a patchwork fashion that no longer fully reflect current practice due to subsequent advances in OSA diagnosis, treatment, and technology. Based on searches of medical literature, internet materials, and reference lists from existing publications, an overview and discussion of key published recommendations regarding OSA assessment and treatment in CMV operators is provided. Suggestions for incorporating these recommendations into clinical sleep medicine practice in the U.S. are presented. The challenge for sleep specialists is maintaining the delicate balance between recommendations impacting standard of care and associated medico-legal impact with stakeholder interests from medical, regulatory, industry and public perspectives while providing high quality and efficient care. Citation: Colvin LJ, Collop NA. Commercial motor vehicle driver obstructive sleep apnea screening and treatment in the United States: an update and recommendation overview. J Clin Sleep Med 2016;12(1):113–125. PMID:26094916

  4. Drivers of the OCT market growth in clinical applications

    NASA Astrophysics Data System (ADS)

    Bouyé, Clémentine; d'Humières, Benoît.

    2015-03-01

    The development of Optical Coherence Tomography (OCT) systems started in the 1990's. The technology early found its application in Ophthalmology. Today more than 75% of the OCT market comes from the ophthalmic sector. However the growth of the ophthalmology OCT market has been slowing down for the last years. In this article, we present the results of our prospective study on the drivers of the OCT market growth in the coming years, based on bibliographical research and interviews with key players. In parallel of being used for ophthalmology, OCT has been developed and tested in new medical domains like cardiology, dermatology, gastroenterology, etc. OCT addresses key societal challenges such as the diagnosis of coronary artery diseases or skin cancer. There is a strong demand for fast, high-resolution, label-free and in vivo imaging tools in these fields. For the last 5 years, RD efforts have been focused on improving the performance and the compactness of OCT components and sub-systems. Advances in integrated photonics will enable the miniaturization of components and sub-systems and thus pave the way to Point-of-Care applications. Moreover the developments of new functionalities of OCT systems are undertaken to reach more complex diagnosis. OCT will no longer be a simple imaging device, it is on the verge of becoming a quantitative measurement tool. Our study shows that the emergence of new applications along with the improvements of components performance and the progress of functional OCT will drive the OCT market growth in the coming years.

  5. Reducing Cancelations on the Day of Scheduled Surgery at a Children's Hospital.

    PubMed

    Pratap, Jayant Nick; Varughese, Anna M; Mercurio, Patti; Lynch, Terri; Lonnemann, Teresa; Ellis, Andrea; Rugg, John; Stone, W Ray; Bedinghaus, Cindi

    2015-05-01

    Cancelation on the day of surgery (DoSC) represents a costly wastage of operating room (OR) time and causes inconvenience, emotional distress, and financial cost to families. A quality improvement project sought to reduce lost OR time due to cancelation. Key drivers of the process included effective 2-way communication with families, compliance with fasting rules, and decision-making on patient illness before the day of surgery. A multidisciplinary team conducted serial tests of change addressing the various key drivers. Interventions were simplified, colorful, personalized preoperative instruction sheets and text-message reminders to caregivers' cellphones, as well as a defined institutional decision-making pathway to permit rescheduling before the day of surgery in case of patient illness concerns. After initial smaller-scale testing, the interventions were implemented across all patients and sites. Data were collected from the hospital information technology system and analyzed by using control charts and statistical process control methods. Mean OR time lost due to DoSC was decreased from a baseline of 5.7 to 3.6 hours/day in testing with a subset of surgical services at the hospital's base campus, and then from 6.6 hours to 5.5 hours/day when implemented across all services at both surgical sites. By applying quality improvement methods, significant reductions were made in time lost due to DoSC. The impact can be significant by improving institutional resource utilization. Copyright © 2015 by the American Academy of Pediatrics.

  6. Transportation Energy Futures Series: Non-Cost Barriers to Consumer Adoption of New Light-Duty Vehicle Technologies

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stephens, T.

    2013-03-01

    Consumer preferences are key to the adoption of new vehicle technologies. Barriers to consumer adoption include price and other obstacles, such as limited driving range and charging infrastructure; unfamiliarity with the technology and uncertainty about direct benefits; limited makes and models with the technology; reputation or perception of the technology; standardization issues; and regulations. For each of these non-cost barriers, this report estimates an effective cost and summarizes underlying influences on consumer preferences, approximate magnitude and relative severity, and assesses potential actions, based on a comprehensive literature review. While the report concludes that non-cost barriers are significant, effective cost andmore » potential market share are very uncertain. Policies and programs including opportunities for drivers to test drive advanced vehicles, general public outreach and information programs, incentives for providing charging and fueling infrastructure, and development of technology standards were examined for their ability to address barriers, but little quantitative data exists on the effectiveness of these measures. This is one in a series of reports produced as a result of the Transportation Energy Futures project, a Department of Energy-sponsored multi-agency effort to pinpoint underexplored strategies for reducing GHGs and petroleum dependence related to transportation.« less

  7. Examining Tensions That Affect the Evaluation of Technology in Health Care: Considerations for System Decision Makers From the Perspective of Industry and Evaluators.

    PubMed

    Desveaux, Laura; Shaw, James; Wallace, Ross; Bhattacharyya, Onil; Bhatia, R Sacha; Jamieson, Trevor

    2017-12-08

    Virtual technologies have the potential to mitigate a range of challenges for health care systems. Despite the widespread use of mobile devices in everyday life, they currently have a limited role in health service delivery and clinical care. Efforts to integrate the fast-paced consumer technology market with health care delivery exposes tensions among patients, providers, vendors, evaluators, and system decision makers. This paper explores the key tensions between the high bar for evidence prior to market approval that guides health care regulatory decisions and the "fail fast" reality of the technology industry. We examine three core tensions: balancing user needs versus system needs, rigor versus responsiveness, and the role of pre- versus postmarket evidence generation. We use these to elaborate on the structure and appropriateness of evaluation mechanisms for virtual care solutions. Virtual technologies provide a foundation for personalized, patient-centered medicine on the user side, coupled with a broader understanding of impact on the system side. However, mechanisms for stakeholder discussion are needed to clarify the nature of the health technology marketplace and the drivers of evaluation priorities. ©Laura Desveaux, James Shaw, Ross Wallace, Onil Bhattacharyya, R Sacha Bhatia, Trevor Jamieson. Originally published in JMIR Medical Informatics (http://medinform.jmir.org), 08.12.2017.

  8. Telecommunications IT and navigation for future Mars exploration missions 2006 IEEE Aerospace Conference

    NASA Technical Reports Server (NTRS)

    Wyatt, E. Jay; Ely, Todd A.; Klimesh, Matthew A.; Krupiarz, Christopher J.

    2006-01-01

    There are three primary drivers behind current investments in telecommunications information technology and navigation. One is finding ways to maximize the volume of science data returned from missions since i nstrument data generation often exceeds communication bandwidth. Another is to provide the necessary technology to enable networked spacecraft around Mars. The third driver is to enable more precise landing so in-situ vehicles can be placed in the more scientifically interesting regions. This paper describes the current NASA investments in these areas funded through the NASA Mars Technology Base Program NRA.

  9. Using shadow page cache to improve isolated drivers performance.

    PubMed

    Zheng, Hao; Dong, Xiaoshe; Wang, Endong; Chen, Baoke; Zhu, Zhengdong; Liu, Chengzhe

    2015-01-01

    With the advantage of the reusability property of the virtualization technology, users can reuse various types and versions of existing operating systems and drivers in a virtual machine, so as to customize their application environment. In order to prevent users' virtualization environments being impacted by driver faults in virtual machine, Chariot examines the correctness of driver's write operations by the method of combining a driver's write operation capture and a driver's private access control table. However, this method needs to keep the write permission of shadow page table as read-only, so as to capture isolated driver's write operations through page faults, which adversely affect the performance of the driver. Based on delaying setting frequently used shadow pages' write permissions to read-only, this paper proposes an algorithm using shadow page cache to improve the performance of isolated drivers and carefully study the relationship between the performance of drivers and the size of shadow page cache. Experimental results show that, through the shadow page cache, the performance of isolated drivers can be greatly improved without impacting Chariot's reliability too much.

  10. Using Shadow Page Cache to Improve Isolated Drivers Performance

    PubMed Central

    Dong, Xiaoshe; Wang, Endong; Chen, Baoke; Zhu, Zhengdong; Liu, Chengzhe

    2015-01-01

    With the advantage of the reusability property of the virtualization technology, users can reuse various types and versions of existing operating systems and drivers in a virtual machine, so as to customize their application environment. In order to prevent users' virtualization environments being impacted by driver faults in virtual machine, Chariot examines the correctness of driver's write operations by the method of combining a driver's write operation capture and a driver's private access control table. However, this method needs to keep the write permission of shadow page table as read-only, so as to capture isolated driver's write operations through page faults, which adversely affect the performance of the driver. Based on delaying setting frequently used shadow pages' write permissions to read-only, this paper proposes an algorithm using shadow page cache to improve the performance of isolated drivers and carefully study the relationship between the performance of drivers and the size of shadow page cache. Experimental results show that, through the shadow page cache, the performance of isolated drivers can be greatly improved without impacting Chariot's reliability too much. PMID:25815373

  11. Implementing managerial innovations in primary care: can we rank change drivers in complex adaptive organizations?

    PubMed

    Longo, Francesco

    2007-01-01

    There has been much innovation in primary care in the past few decades. Although external and systemic constraints for health care organizations are relevant for their managerial evolution, there is also evidence that organizations operating under the same external pressures reach different levels of maturity. Which of the internal drivers available explain and foster change? Is it possible to rank change drivers by looking at their rate of efficacy in order to define a general change management path in the relationship between managers and physicians? The study is a hypothesis-generating work, designed to discuss a framework, consistent with the complex adaptive systems literature, for more effective internal change management approaches. We employed a qualitative approach to conduct a multiple case study in order to directly observe the evidence and to ask "key change players" for their perceptions. We studied different organizations all subject to the same external constraints in order to focus on the effects of internal change drivers. According to key players' opinions, the main drivers for managerial development are characteristics of the actors involved: their motivation, leadership, and commitment; the quality of relationships among the main actors; and how the resources dedicated to manage change are used. Given these criteria, any organizational strategy and goal seems to be achievable. This is consistent with the suggestions coming from the complex adaptive system literature. MANAGERIAL IMPLICATIONS: Managers have to consider the management of the relationship with professionals as the key success factor for implementing change. Managerial leadership has to be diffused in the organization both in the vertical and horizontal dimensions. Innovations need a medium or long-term perspective to become widely applied, and this requires a strong commitment which is related to managerial stability. Resources for innovation are to be considered a critical driver for fostering the relationship between managers and professionals.

  12. The effects of mutational processes and selection on driver mutations across cancer types.

    PubMed

    Temko, Daniel; Tomlinson, Ian P M; Severini, Simone; Schuster-Böckler, Benjamin; Graham, Trevor A

    2018-05-10

    Epidemiological evidence has long associated environmental mutagens with increased cancer risk. However, links between specific mutation-causing processes and the acquisition of individual driver mutations have remained obscure. Here we have used public cancer sequencing data from 11,336 cancers of various types to infer the independent effects of mutation and selection on the set of driver mutations in a cancer type. First, we detect associations between a range of mutational processes, including those linked to smoking, ageing, APOBEC and DNA mismatch repair (MMR) and the presence of key driver mutations across cancer types. Second, we quantify differential selection between well-known alternative driver mutations, including differences in selection between distinct mutant residues in the same gene. These results show that while mutational processes have a large role in determining which driver mutations are present in a cancer, the role of selection frequently dominates.

  13. Driver attitudes and behaviors at intersections and potential effectiveness of engineering countermeasures

    DOT National Transportation Integrated Search

    2005-11-01

    The objective of this focus group study was to identify driver attitudes and behaviors related to intersection safety and to assess the likely impacts of new or existing infrastructure-based technologies/countermeasures. Four focus groups were conduc...

  14. Guidelines and recommendations to accommodate older driver and pedestrians

    DOT National Transportation Integrated Search

    2001-05-01

    This project updated, revised, and expanded the scope of the Older Driver Highway Design Handbook published by FHWA in 1998. Development of the updated Handbook (FHWA-RD-01-103) was complemented by a technology transfer initiative to make practitione...

  15. Functional annotation of rare gene aberration drivers of pancreatic cancer | Office of Cancer Genomics

    Cancer.gov

    As we enter the era of precision medicine, characterization of cancer genomes will directly influence therapeutic decisions in the clinic. Here we describe a platform enabling functionalization of rare gene mutations through their high-throughput construction, molecular barcoding and delivery to cancer models for in vivo tumour driver screens. We apply these technologies to identify oncogenic drivers of pancreatic ductal adenocarcinoma (PDAC).

  16. IFE Chamber Technology - Status and Future Challenges

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Meier, W.R.; Raffray, A.R.; Abdel-Khalik, S.I.

    2003-07-15

    Significant progress has been made on addressing critical issues for inertial fusion energy (IFE) chambers for heavy-ion, laser and Z-pinch drivers. A variety of chamber concepts are being investigated including drywall (currently favored for laser IFE), wetted-wall (applicable to both laser and ion drivers), and thick-liquid-wall (favored by heavy ion and z-pinch drivers). Recent progress and remaining challenges in developing IFE chambers are reviewed.

  17. Using microsimulation to evaluate the effects of advanced vehicle technologies on congestion.

    DOT National Transportation Integrated Search

    2011-06-30

    Advanced driver assistance technologies are continuously being developed to enhance traffic : safety. Evaluations of such technologies typically focus on safety and there has been limited : research on the impacts of such technologies on traffic oper...

  18. Using Microsimulation to Evaluate the Effects of Advanced Vehicle Technologies on Congestion

    DOT National Transportation Integrated Search

    2011-06-30

    Advanced driver assistance technologies are continuously being developed to enhance traffic safety. Evaluations of such technologies typically focus on safety and there has been limited research on the impacts of such technologies on traffic operatio...

  19. NASA's Solar Dynamics Observatory (SDO): A Systems Approach to a Complex Mission

    NASA Technical Reports Server (NTRS)

    Ruffa, John A.; Ward, David K.; Bartusek, LIsa M.; Bay, Michael; Gonzales, Peter J.; Pesnell, William D.

    2012-01-01

    The Solar Dynamics Observatory (SDO) includes three advanced instruments, massive science data volume, stringent science data completeness requirements, and a custom ground station to meet mission demands. The strict instrument science requirements imposed a number of challenging drivers on the overall mission system design, leading the SDO team to adopt an integrated systems engineering presence across all aspects of the mission to ensure that mission science requirements would be met. Key strategies were devised to address these system level drivers and mitigate identified threats to mission success. The global systems engineering team approach ensured that key drivers and risk areas were rigorously addressed through all phases of the mission, leading to the successful SDO launch and on-orbit operation. Since launch, SDO's on-orbit performance has met all mission science requirements and enabled groundbreaking science observations, expanding our understanding of the Sun and its dynamic processes.

  20. NASA's Solar Dynamics Observatory (SDO): A Systems Approach to a Complex Mission

    NASA Technical Reports Server (NTRS)

    Ruffa, John A.; Ward, David K.; Bartusek, Lisa M.; Bay, Michael; Gonzales, Peter J.; Pesnell, William D.

    2012-01-01

    The Solar Dynamics Observatory (SDO) includes three advanced instruments, massive science data volume, stringent science data completeness requirements, and a custom ground station to meet mission demands. The strict instrument science requirements imposed a number of challenging drivers on the overall mission system design, leading the SDO team to adopt an integrated systems engineering presence across all aspects of the mission to ensure that mission science requirements would be met. Key strategies were devised to address these system level drivers and mitigate identified threats to mission success. The global systems engineering team approach ensured that key drivers and risk areas were rigorously addressed through all phases of the mission, leading to the successful SDO launch and on-orbit operation. Since launch, SDO s on-orbit performance has met all mission science requirements and enabled groundbreaking science observations, expanding our understanding of the Sun and its dynamic processes.

  1. Wood phenology: from organ-scale processes to terrestrial ecosystem models

    NASA Astrophysics Data System (ADS)

    Delpierre, Nicolas; Guillemot, Joannès

    2016-04-01

    In temperate and boreal trees, a dormancy period prevents organ development during adverse climatic conditions. Whereas the phenology of leaves and flowers has received considerable attention, to date, little is known regarding the phenology of other tree organs such as wood, fine roots, fruits and reserve compounds. In this presentation, we review both the role of environmental drivers in determining the phenology of wood and the models used to predict its phenology in temperate and boreal forest trees. Temperature is a key driver of the resumption of wood activity in spring. There is no such clear dominant environmental cue involved in the cessation of wood formation in autumn, but temperature and water stress appear as prominent factors. We show that wood phenology is a key driver of the interannual variability of wood growth in temperate tree species. Incorporating representations of wood phenology in a terrestrial ecosystem model substantially improved the simulation of wood growth under current climate.

  2. Delivery of agricultural technology to resource-poor farmers in Africa.

    PubMed

    Mignouna, Hodeba D; Abang, Mathew M; Omanya, Gospel; Nang'ayo, Francis; Bokanga, Mpoko; Boadi, Richard; Muchiri, Nancy; Terry, Eugene

    2008-01-01

    Recent developments in agricultural science and technology have the potential to transform the agricultural sector in the developing world. These technological advances constitute key drivers of economic growth and hold great promise for poverty reduction in sub-Saharan Africa (SSA). Agricultural research and development in Africa is undergoing a major paradigm shift. Until recently, public-sector institutions in Africa worked in isolation to create and disseminate agricultural technologies to smallholder farmers. However, they need access to improved proprietary technologies developed for the most part by the private sector in developed countries. These technologies are currently concentrated in the hands of a few large corporations and are protected by intellectual property rights. The African Agricultural Technology Foundation (AATF) is a new initiative addressing the challenges associated with the access, development, and deployment of agricultural technologies to smallholder farmers in SSA. This article describes the AATF model of facilitating the creation of partnership alliances dedicated to promote and support collaboration among a wide variety of public- and private-sector organizations around shared agricultural research and development goals for the public good. It explains AATF's public-private partnership framework for technology delivery in the light of market failures, institutional constraints, and systemic weaknesses, which impede public-sector organizations from accessing and delivering pro-poor knowledge and technology to farmers. The article provides policy makers, research managers, and business decision makers with an understanding of how access to, and delivery of, proprietary technologies could contribute to food security and the improvement of farmers' livelihoods in Africa.

  3. Challenges and opportunities in genetic improvement of local livestock breeds

    PubMed Central

    Biscarini, Filippo; Nicolazzi, Ezequiel L.; Stella, Alessandra; Boettcher, Paul J.; Gandini, Gustavo

    2015-01-01

    Sufficient genetic variation in livestock populations is necessary both for adaptation to future changes in climate and consumer demand, and for continual genetic improvement of economically important traits. Unfortunately, the current trend is for reduced genetic variation, both within and across breeds. The latter occurs primarily through the loss of small, local breeds. Inferior production is a key driver for loss of small breeds, as they are replaced by high-output international transboundary breeds. Selection to improve productivity of small local breeds is therefore critical for their long term survival. The objective of this paper is to review the technology options available for the genetic improvement of small local breeds and discuss their feasibility. Most technologies have been developed for the high-input breeds and consequently are more favorably applied in that context. Nevertheless, their application in local breeds is not precluded and can yield significant benefits, especially when multiple technologies are applied in close collaboration with farmers and breeders. Breeding strategies that require cooperation and centralized decision-making, such as optimal contribution selection, may in fact be more easily implemented in small breeds. PMID:25763010

  4. Molecular profiling of cancer--the future of personalized cancer medicine: a primer on cancer biology and the tools necessary to bring molecular testing to the clinic.

    PubMed

    Stricker, Thomas; Catenacci, Daniel V T; Seiwert, Tanguy Y

    2011-04-01

    Cancers arise as a result of an accumulation of genetic aberrations that are either acquired or inborn. Virtually every cancer has its unique set of molecular changes. Technologies have been developed to study cancers and derive molecular characteristics that increasingly have implications for clinical care. Indeed, the identification of key genetic aberrations (molecular drivers) may ultimately translate into dramatic benefit for patients through the development of highly targeted therapies. With the increasing availability of newer, more powerful, and cheaper technologies such as multiplex mutational screening, next generation sequencing, array-based approaches that can determine gene copy numbers, methylation, expression, and others, as well as more sophisticated interpretation of high-throughput molecular information using bioinformatics tools like signatures and predictive algorithms, cancers will routinely be characterized in the near future. This review examines the background information and technologies that clinicians and physician-scientists will need to interpret in order to develop better, personalized treatment strategies. Copyright © 2011 Elsevier Inc. All rights reserved.

  5. Emerging memories

    NASA Astrophysics Data System (ADS)

    Baldi, Livio; Bez, Roberto; Sandhu, Gurtej

    2014-12-01

    Memory is a key component of any data processing system. Following the classical Turing machine approach, memories hold both the data to be processed and the rules for processing them. In the history of microelectronics, the distinction has been rather between working memory, which is exemplified by DRAM, and storage memory, exemplified by NAND. These two types of memory devices now represent 90% of all memory market and 25% of the total semiconductor market, and have been the technology drivers in the last decades. Even if radically different in characteristics, they are however based on the same storage mechanism: charge storage, and this mechanism seems to be near to reaching its physical limits. The search for new alternative memory approaches, based on more scalable mechanisms, has therefore gained new momentum. The status of incumbent memory technologies and their scaling limitations will be discussed. Emerging memory technologies will be analyzed, starting from the ones that are already present for niche applications, and which are getting new attention, thanks to recent technology breakthroughs. Maturity level, physical limitations and potential for scaling will be compared to existing memories. At the end the possible future composition of memory systems will be discussed.

  6. Transportation and Aging: A Research Agenda for Advancing Safe Mobility

    ERIC Educational Resources Information Center

    Dickerson, Anne E.; Molnar, Lisa J.; Eby, David W.; Adler, Geri; Bedard, Michel; Berg-Weger, Marla; Classen, Sherrilene; Foley, Daniel; Horowitz, Amy; Kerschner, Helen; Page, Oliver; Silverstein, Nina M.; Staplin, Loren; Trujillo, Leonard

    2007-01-01

    Purpose: We review what we currently know about older driver safety and mobility, and we highlight important research needs in a number of key areas that hold promise for achieving the safety and mobility goals for the aging baby boomers and future generations of older drivers. Design and Methods: Through the use of a framework for transportation…

  7. Driver alertness and fatigue : summary of completed research projects, 1995-98

    DOT National Transportation Integrated Search

    2000-01-01

    This document describes projects in the Federal Motor Carrier Safety Administration's (FMCSA) Driver Alertness and Fatigue Research and Technology (R&T) focus area that were completed during the years 1995 to 1998 under the former Office of Motor Car...

  8. The costs and consequences of assisted reproductive technology: an economic perspective.

    PubMed

    Connolly, Mark P; Hoorens, Stijn; Chambers, Georgina M

    2010-01-01

    Despite the growing use of assisted reproductive technologies (ART) worldwide, there is only a limited understanding of the economics of ART to inform policy about effective, safe and equitable financing of ART treatment. A review was undertaken of key studies regarding the costs and consequences of ART treatment, specifically examining the direct and indirect costs of treatment, economic drivers of utilization and clinical practice and broader economic consequences of ART-conceived children. The direct costs of ART treatment vary substantially between countries, with the USA standing out as the most expensive. The direct costs generally reflect the costliness of the underlying healthcare system. If unsubsidized, direct costs represent a significant economic burden to patients. The level of affordability of ART treatment is an important driver of utilization, treatment choices, embryo transfer practices and ultimately multiple birth rates. The costs associated with caring for multiple-birth ART infants and their mothers are substantial, reflecting the underlying morbidity associated with such pregnancies. Investment analysis of ART treatment and ART-conceived children indicates that appropriate funding of ART services appears to represent sound fiscal policy. The complex interaction between the cost of ART treatment and how treatments are subsidized in different healthcare settings and for different patient groups has far-reaching consequences for ART utilization, clinical practice and infant outcomes. A greater understanding of the economics of ART is needed to inform policy decisions and to ensure the best possible outcomes from ART treatment.

  9. DriveID: safety innovation through individuation.

    PubMed

    Sawyer, Ben; Teo, Grace; Mouloua, Mustapha

    2012-01-01

    The driving task is highly complex and places considerable perceptual, physical and cognitive demands on the driver. As driving is fundamentally an information processing activity, distracted or impaired drivers have diminished safety margins compared with non- distracted drivers (Hancock and Parasuraman, 1992; TRB 1998 a & b). This competition for sensory and decision making capacities can lead to failures that cost lives. Some groups, teens and elderly drivers for example, have patterns of systematically poor perceptual, physical and cognitive performance while driving. Although there are technologies developed to aid these different drivers, these systems are often misused and underutilized. The DriveID project aims to design and develop a passive, automated face identification system capable of robustly identifying the driver of the vehicle, retrieve a stored profile, and intelligently prescribing specific accident prevention systems and driving environment customizations.

  10. Therapeutic modulation of epigenetic drivers of drug resistance in ovarian cancer

    PubMed Central

    Zeller, Constanze; Brown, Robert

    2010-01-01

    Epigenetic changes in tumours are associated not only with cancer development and progression, but also with resistance to chemotherapy. Aberrant DNA methylation at CpG islands and associated epigenetic silencing are observed during the acquisition of drug resistance. However, it remains unclear whether all of the observed changes are drivers of drug resistance, causally associated with response of tumours to chemotherapy, or are passenger events representing chance DNA methylation changes. Systematic approaches that link DNA methylation and expression with chemosensitivity will be required to identify key drivers. Such drivers will be important prognostic or predicitive biomarkers, both to existing chemotherapies, but also to epigenetic therapies used to modulate drug resistance. PMID:21789144

  11. Health Systems and Sustainability: Doctors and Consumers Differ on Threats and Solutions

    PubMed Central

    Robertson, Jane; Walkom, Emily J.; Henry, David A.

    2011-01-01

    Background Healthcare systems face the problem of insufficient resources to meet the needs of ageing populations and increasing demands for access to new treatments. It is unclear whether doctors and consumers agree on the main challenges to health system sustainability. Methodology We conducted a mail survey of Australian doctors (specialists and general practitioners) and a computer assisted telephone interview (CATI) of consumers to determine their views on contributors to increasing health care costs, rationing of services and involvement in health resource allocation decisions. Differences in responses are reported as odds ratios (OR) and 99% confidence intervals (CI). Results Of 2948 doctors, 1139 (38.6%) responded; 533 of 826 consumers responded (64.5% response). Doctors were more concerned than consumers with the effects of an ageing population (OR 3.0; 99% CI 1.7, 5.4), and costs of new drugs and technologies (OR 5.1; CI 3.3, 8.0), but less likely to consider pharmaceutical promotional activities as a cost driver (OR 0.29, CI 0.22, 0.39). Doctors were more likely than consumers to view ‘community demand’ for new technologies as a major cost driver, (OR 1.6; 1.2, 2.2), but less likely to attribute increased costs to patients failing to take responsibility for their own health (OR 0.35; 0.24, 0.49). Like doctors, the majority of consumers saw a need for public consultation in decisions about funding for new treatments. Conclusions Australian doctors and consumers hold different views on the sustainability of the healthcare system, and a number of key issues relating to costs, cost drivers, roles and responsibilities. Doctors recognise their dual responsibility to patients and society, see an important role for physicians in influencing resource allocation, and acknowledge their lack of skills in assessing treatments of marginal value. Consumers recognise cost pressures on the health system, but express willingness to be involved in health care decision making. PMID:21556357

  12. Prioritizing Information Technology Investments: Assessing the Correlations among Technological Readiness, Information Technology Flexibility, and Information Technology Effectiveness

    ERIC Educational Resources Information Center

    Walter, John T.

    2010-01-01

    Management's dilemma, when allocating financial resources towards the improvement of technological readiness and IT flexibility within their organizations, is to control financial risk and maximize IT effectiveness. Technological readiness is people's propensity to embrace and use technology. Its drivers are optimism, innovativeness, discomfort,…

  13. Origins Space Telescope

    NASA Astrophysics Data System (ADS)

    Cooray, Asantha; Origins Space Telescope Study Team

    2018-01-01

    The Origins Space Telescope (OST) is the mission concept for the Far-Infrared Surveyor, a study in development by NASA in preparation for the 2020 Astronomy and Astrophysics Decadal Survey. Origins is planned to be a large aperture, actively-cooled telescope covering a wide span of the mid- to far-infrared spectrum. Its spectrographs will enable 3D surveys of the sky that will discover and characterize the most distant galaxies, Milky-Way, exoplanets, and the outer reaches of our Solar system. Origins will enable flagship-quality general observing programs led by the astronomical community in the 2030s. The Science and Technology Definition Team (STDT) would like to hear your science needs and ideas for this mission. The team can be contacted at firsurveyor_info@lists.ipac.caltech.edu. This presentation will provide a summary of the OST STDT, our completed first mission concept and an introduction to the second concept that will be studied at the study center in 2018. This presentation will also summarize key science drivers and the key study milestones between 2018 and 2020.

  14. Trends in food waste valorization for the production of chemicals, materials and fuels: Case study South and Southeast Asia.

    PubMed

    Ong, Khai Lun; Kaur, Guneet; Pensupa, Nattha; Uisan, Kristiadi; Lin, Carol Sze Ki

    2018-01-01

    Staggering amounts of food waste are being generated in Asia by means of agricultural processing, food transportation and storage, and human food consumption activities. This along with the recent sustainable development goals of food security, environmental protection, and energy efficiency are the key drivers for food waste valorization. The aim of this review is to provide an insight on the latest trends in food waste valorization in Asian countries such as India, Thailand, Singapore, Malaysia and Indonesia. Landfilling, incineration, and composting are the first-generation food waste processing technologies. The advancement of valorisation alternatives to tackle the food waste issue is the focus of this review. Furthermore, a series of examples of key food waste valorization schemes in this Asian region as case studies to demonstrate the advancement in bioconversions in these countries are described. Finally, important legislation aspects for food waste disposal in these Asian countries are also reported. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. Compact SPAD-Based Pixel Architectures for Time-Resolved Image Sensors

    PubMed Central

    Perenzoni, Matteo; Pancheri, Lucio; Stoppa, David

    2016-01-01

    This paper reviews the state of the art of single-photon avalanche diode (SPAD) image sensors for time-resolved imaging. The focus of the paper is on pixel architectures featuring small pixel size (<25 μm) and high fill factor (>20%) as a key enabling technology for the successful implementation of high spatial resolution SPAD-based image sensors. A summary of the main CMOS SPAD implementations, their characteristics and integration challenges, is provided from the perspective of targeting large pixel arrays, where one of the key drivers is the spatial uniformity. The main analog techniques aimed at time-gated photon counting and photon timestamping suitable for compact and low-power pixels are critically discussed. The main features of these solutions are the adoption of analog counting techniques and time-to-analog conversion, in NMOS-only pixels. Reliable quantum-limited single-photon counting, self-referenced analog-to-digital conversion, time gating down to 0.75 ns and timestamping with 368 ps jitter are achieved. PMID:27223284

  16. A global dataset of crowdsourced land cover and land use reference data.

    PubMed

    Fritz, Steffen; See, Linda; Perger, Christoph; McCallum, Ian; Schill, Christian; Schepaschenko, Dmitry; Duerauer, Martina; Karner, Mathias; Dresel, Christopher; Laso-Bayas, Juan-Carlos; Lesiv, Myroslava; Moorthy, Inian; Salk, Carl F; Danylo, Olha; Sturn, Tobias; Albrecht, Franziska; You, Liangzhi; Kraxner, Florian; Obersteiner, Michael

    2017-06-13

    Global land cover is an essential climate variable and a key biophysical driver for earth system models. While remote sensing technology, particularly satellites, have played a key role in providing land cover datasets, large discrepancies have been noted among the available products. Global land use is typically more difficult to map and in many cases cannot be remotely sensed. In-situ or ground-based data and high resolution imagery are thus an important requirement for producing accurate land cover and land use datasets and this is precisely what is lacking. Here we describe the global land cover and land use reference data derived from the Geo-Wiki crowdsourcing platform via four campaigns. These global datasets provide information on human impact, land cover disagreement, wilderness and land cover and land use. Hence, they are relevant for the scientific community that requires reference data for global satellite-derived products, as well as those interested in monitoring global terrestrial ecosystems in general.

  17. Exploration Roadmap Working Group (ERWG) Data Collection, NASA's Inputs

    NASA Technical Reports Server (NTRS)

    Drake, Bret; Landis, Rob; Thomas, Andrew; Mauzy, Susan; Graham, Lee; Culbert, Chris; Troutman, Pat

    2010-01-01

    This slide presentation reviews four areas for further space exploration: (1) Human Exploration of Mars Design Reference Architecture (DRA) 5.0, (2) Robotic Precursors targeting Near Earth Objects (NEO) for Human Exploration, (3) Notional Human Exploration of Near Earth Objects and (4) Low Earth Orbit (LEO) Refueling to Augment Human Exploration. The first presentation reviews the goals and objectives of the Mars DRA, presents a possible mission profile, innovation requirements for the mission and key risks and challenges for human exploration of Mars. The second presentation reviews the objective and goals of the robotic precursors to the NEO and the mission profile of such robotic exploration. The third presentation reviews the mission scenario of human exploration of NEO, the objectives and goals, the mission operational drivers, the key technology needs and a mission profile. The fourth and last presentation reviews the examples of possible refueling in low earth orbit prior to lunar orbit insertion, to allow for larger delivered payloads for a lunar mission.

  18. A global dataset of crowdsourced land cover and land use reference data

    PubMed Central

    Fritz, Steffen; See, Linda; Perger, Christoph; McCallum, Ian; Schill, Christian; Schepaschenko, Dmitry; Duerauer, Martina; Karner, Mathias; Dresel, Christopher; Laso-Bayas, Juan-Carlos; Lesiv, Myroslava; Moorthy, Inian; Salk, Carl F.; Danylo, Olha; Sturn, Tobias; Albrecht, Franziska; You, Liangzhi; Kraxner, Florian; Obersteiner, Michael

    2017-01-01

    Global land cover is an essential climate variable and a key biophysical driver for earth system models. While remote sensing technology, particularly satellites, have played a key role in providing land cover datasets, large discrepancies have been noted among the available products. Global land use is typically more difficult to map and in many cases cannot be remotely sensed. In-situ or ground-based data and high resolution imagery are thus an important requirement for producing accurate land cover and land use datasets and this is precisely what is lacking. Here we describe the global land cover and land use reference data derived from the Geo-Wiki crowdsourcing platform via four campaigns. These global datasets provide information on human impact, land cover disagreement, wilderness and land cover and land use. Hence, they are relevant for the scientific community that requires reference data for global satellite-derived products, as well as those interested in monitoring global terrestrial ecosystems in general. PMID:28608851

  19. Driving with diabetes: precaution, not prohibition, is the proper approach.

    PubMed

    Kohrman, Daniel B

    2013-03-01

    Safety issues posed by driving with diabetes are primarily related to severe hypoglycemia, yet some public authorities rely on categorical restrictions on drivers with diabetes. This approach is misguided. Regulation of all drivers with diabetes, or all drivers using insulin, ignores the diversity of people with diabetes and fails to focus on the subpopulation posing the greatest risk. Advances in diabetes care technology and understanding of safety consequences of diabetes have expanded techniques available to limit risks of driving with diabetes. New means of insulin administration and blood glucose monitoring offer greater ease of anticipating and preventing hypoglycemia, and thus, limit driving risk for persons with diabetes. So too do less sophisticated steps taken by people with diabetes and the health care professionals they consult. These include adoption and endorsement of safety-sensitive behaviors, such as testing before a drive and periodic testing on longer trips. Overall, and in most individual cases, driving risks for persons with diabetes are less than those routinely tolerated by our society. Examples include freedom to drive in dangerous conditions and lax regulation of drivers in age and medical cohorts with elevated overall rates of driving mishaps. Data linking specific diabetes symptoms or features with driving risk are quite uncertain. Hence, there is much to recommend: a focus on technological advances, human precautions, and identifying individuals with diabetes with a specific history of driving difficulty. By contrast, available evidence does not support unfocused regulation of all or most drivers with diabetes. © 2013 Diabetes Technology Society.

  20. A technology to measure multiple driving behaviors without self-report or participant reactivity.

    PubMed Central

    Boyce, T E; Geller, E S

    2001-01-01

    An in-vehicle information system (IVIS) was used to videotape drivers (N = 61) without their knowledge while driving 22 miles in normal traffic. The drivers were told that they were participating in a study of direction following and map reading. Two data-coding procedures were used to analyze videotapes. Safety-related behaviors were counted during consecutive 15-s intervals of a driving trial, and the occurrence of certain safety-related behaviors was assessed under critical conditions. These two methods of data coding were assessed for practicality, reliability, and sensitivity. Interobserver agreement for the five different driving behaviors ranged from 85% to 95%. Within-subject variability in safe driving was more pronounced among younger drivers and decreased as a function of age. Contrary to previous research that has relied on self-reports, driver risk taking did not vary significantly as a function of gender. These results are used to illustrate the capabilities of the technology introduced here to design and evaluate behavior-analytic interventions to increase safe driving. PMID:11317986

  1. Backthinned TDI CCD image sensor design and performance for the Pleiades high resolution Earth observation satellites

    NASA Astrophysics Data System (ADS)

    Materne, A.; Bardoux, A.; Geoffray, H.; Tournier, T.; Kubik, P.; Morris, D.; Wallace, I.; Renard, C.

    2017-11-01

    The PLEIADES-HR Earth observing satellites, under CNES development, combine a 0.7m resolution panchromatic channel, and a multispectral channel allowing a 2.8 m resolution, in 4 spectral bands. The 2 satellites will be placed on a sun-synchronous orbit at an altitude of 695 km. The camera operates in push broom mode, providing images across a 20 km swath. This paper focuses on the specifications, design and performance of the TDI detectors developed by e2v technologies under CNES contract for the panchromatic channel. Design drivers, derived from the mission and satellite requirements, architecture of the sensor and measurement results for key performances of the first prototypes are presented.

  2. Accelerating global access to plant diversity information.

    PubMed

    Lughadha, Eimear Nic; Miller, Chuck

    2009-11-01

    Botanic gardens play key roles in the development and dissemination of plant information resources. Drivers for change have included progress in information technology, growing public expectations of electronic access and international conservation policy. Great advances have been made in the quantity, quality and accessibility of plant information in digital form and the extent to which information from multiple providers can be accessed through a single portal. However, significant challenges remain to be addressed in making botanic gardens resources maximally accessible and impactful, not least the overwhelming volume of material which still awaits digitisation. The year 2010 represents an opportunity for botanic gardens to showcase their collaborative achievements in delivery of electronic plant information and reinforce their relevance to pressing environmental issues.

  3. Refuse and the 'Risk Society': The Political Ecology of Risk in Inter-war Britain.

    PubMed

    Cooper, Timothy; Bulmer, Sarah

    2013-05-01

    This article responds to current critiques of Ulrich Beck's 'risk society' thesis by historians of science and medicine. Those who have engaged with the concept of risk society have been content to accept the fundamental categories of Beck's analysis. In contrast, we argue that Beck's risk society thesis underplays two key themes. First, the role of capitalist social relations as the driver of technological change and the transformation of everyday life; and second, the ways in which hegemonic discourses of risk can be appropriated and transformed by counter-hegemonic forces. In place of 'risk society', we propose an approach based upon a 'political ecology of risk', which emphasises the social relations that are fundamental to the everyday politics of environmental health.

  4. Robust optical sensors for safety critical automotive applications

    NASA Astrophysics Data System (ADS)

    De Locht, Cliff; De Knibber, Sven; Maddalena, Sam

    2008-02-01

    Optical sensors for the automotive industry need to be robust, high performing and low cost. This paper focuses on the impact of automotive requirements on optical sensor design and packaging. Main strategies to lower optical sensor entry barriers in the automotive market include: Perform sensor calibration and tuning by the sensor manufacturer, sensor test modes on chip to guarantee functional integrity at operation, and package technology is key. As a conclusion, optical sensor applications are growing in automotive. Optical sensor robustness matured to the level of safety critical applications like Electrical Power Assisted Steering (EPAS) and Drive-by-Wire by optical linear arrays based systems and Automated Cruise Control (ACC), Lane Change Assist and Driver Classification/Smart Airbag Deployment by camera imagers based systems.

  5. Mass and power modeling of communication satellites

    NASA Technical Reports Server (NTRS)

    Price, Kent M.; Pidgeon, David; Tsao, Alex

    1991-01-01

    Analytic estimating relationships for the mass and power requirements for major satellite subsystems are described. The model for each subsystem is keyed to the performance drivers and system requirements that influence their selection and use. Guidelines are also given for choosing among alternative technologies which accounts for other significant variables such as cost, risk, schedule, operations, heritage, and life requirements. These models are intended for application to first order systems analyses, where resources do not warrant detailed development of a communications system scenario. Given this ground rule, the models are simplified to 'smoothed' representation of reality. Therefore, the user is cautioned that cost, schedule, and risk may be significantly impacted where interpolations are sufficiently different from existing hardware as to warrant development of new devices.

  6. Planet Formation Imager (PFI): science vision and key requirements

    NASA Astrophysics Data System (ADS)

    Kraus, Stefan; Monnier, John D.; Ireland, Michael J.; Duchêne, Gaspard; Espaillat, Catherine; Hönig, Sebastian; Juhasz, Attila; Mordasini, Chris; Olofsson, Johan; Paladini, Claudia; Stassun, Keivan; Turner, Neal; Vasisht, Gautam; Harries, Tim J.; Bate, Matthew R.; Gonzalez, Jean-François; Matter, Alexis; Zhu, Zhaohuan; Panic, Olja; Regaly, Zsolt; Morbidelli, Alessandro; Meru, Farzana; Wolf, Sebastian; Ilee, John; Berger, Jean-Philippe; Zhao, Ming; Kral, Quentin; Morlok, Andreas; Bonsor, Amy; Ciardi, David; Kane, Stephen R.; Kratter, Kaitlin; Laughlin, Greg; Pepper, Joshua; Raymond, Sean; Labadie, Lucas; Nelson, Richard P.; Weigelt, Gerd; ten Brummelaar, Theo; Pierens, Arnaud; Oudmaijer, Rene; Kley, Wilhelm; Pope, Benjamin; Jensen, Eric L. N.; Bayo, Amelia; Smith, Michael; Boyajian, Tabetha; Quiroga-Nuñez, Luis Henry; Millan-Gabet, Rafael; Chiavassa, Andrea; Gallenne, Alexandre; Reynolds, Mark; de Wit, Willem-Jan; Wittkowski, Markus; Millour, Florentin; Gandhi, Poshak; Ramos Almeida, Cristina; Alonso Herrero, Almudena; Packham, Chris; Kishimoto, Makoto; Tristram, Konrad R. W.; Pott, Jörg-Uwe; Surdej, Jean; Buscher, David; Haniff, Chris; Lacour, Sylvestre; Petrov, Romain; Ridgway, Steve; Tuthill, Peter; van Belle, Gerard; Armitage, Phil; Baruteau, Clement; Benisty, Myriam; Bitsch, Bertram; Paardekooper, Sijme-Jan; Pinte, Christophe; Masset, Frederic; Rosotti, Giovanni

    2016-08-01

    The Planet Formation Imager (PFI) project aims to provide a strong scientific vision for ground-based optical astronomy beyond the upcoming generation of Extremely Large Telescopes. We make the case that a breakthrough in angular resolution imaging capabilities is required in order to unravel the processes involved in planet formation. PFI will be optimised to provide a complete census of the protoplanet population at all stellocentric radii and over the age range from 0.1 to 100 Myr. Within this age period, planetary systems undergo dramatic changes and the final architecture of planetary systems is determined. Our goal is to study the planetary birth on the natural spatial scale where the material is assembled, which is the "Hill Sphere" of the forming planet, and to characterise the protoplanetary cores by measuring their masses and physical properties. Our science working group has investigated the observational characteristics of these young protoplanets as well as the migration mechanisms that might alter the system architecture. We simulated the imprints that the planets leave in the disk and study how PFI could revolutionise areas ranging from exoplanet to extragalactic science. In this contribution we outline the key science drivers of PFI and discuss the requirements that will guide the technology choices, the site selection, and potential science/technology tradeoffs.

  7. "Good Passengers and Not Good Passengers:" Adolescent Drivers' Perceptions About Inattention and Peer Passengers.

    PubMed

    McDonald, Catherine C; Sommers, Marilyn S

    The purpose of this qualitative focus group elicitation research study was to explore teen driver perceptions of peer passengers and driver inattention. We utilized focus groups for data collection and content analysis to analyze the data, both of which were guided by the theory of planned behavior. We conducted 7 focus groups with 30 teens, ages 16-18, licensed for ≤1year to examine attitudes, perceived behavioral control, and norms related to driving inattention and peer passengers. The sample was 50% male, mean age 17.39 (SD 0.52) with mean length of licensure 173.7days (SD 109.2). Three themes emerged: 1) "Good and not good" passengers; 2) Passengers and technology as harmful and helpful; and 3) The driver is in charge. While passengers can be a source of distraction, our participants also identified passenger behaviors that reduced risk, such as assistance with technology and guidance for directions. An understanding of teens' perceptions of peer passengers can contribute to the development of effective interventions targeting teen driver inattention. Nurses are well-positioned to contribute to these teen crash prevention efforts. Copyright © 2016 Elsevier Inc. All rights reserved.

  8. Leveraging accelerated testing of LED drivers to model the reliability of two-stage and multi-channel drivers

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Davis, Lynn; Perkins, Curtis; Smith, Aaron

    The next wave of LED lighting technology is likely to be tunable white lighting (TWL) devices which can adjust the colour of the emitted light between warm white (~ 2700 K) and cool white (~ 6500 K). This type of lighting system uses LED assemblies of two or more colours each controlled by separate driver channels that independently adjust the current levels to achieve the desired lighting colour. Drivers used in TWL devices are inherently more complex than those found in simple SSL devices, due to the number of electrical components in the driver required to achieve this level ofmore » control. The reliability of such lighting systems can only be studied using accelerated stress tests (AST) that accelerate the aging process to time frames that can be accommodated in laboratory testing. This paper describes AST methods and findings developed from AST data that provide insights into the lifetime of the main components of one-channel and multi-channel LED devices. The use of AST protocols to confirm product reliability is necessary to ensure that the technology can meet the performance and lifetime requirements of the intended application.« less

  9. The PLX- α project: demonstrating the viability of spherically imploding plasma liners as an MIF driver

    NASA Astrophysics Data System (ADS)

    Hsu, S. C.; Witherspoon, F. D.; Cassibry, J. T.; Gilmore, M.; Samulyak, R.; Stoltz, P.; the PLX-α Team

    2015-11-01

    Under ARPA-E's ALPHA program, the Plasma Liner Experiment-ALPHA (PLX- α) project aims to demonstrate the viability and scalability of spherically imploding plasma liners as a standoff, high-implosion-velocity magneto-inertial-fusion (MIF) driver that is potentially compatible with both low- and high- β targets. The project has three major objectives: (a) advancing existing contoured-gap coaxial-gun technology to achieve higher operational reliability/precision and better control/reproducibility of plasma-jet properties and profiles; (2) conducting ~ π / 2 -solid-angle plasma-liner experiments with 9 guns to demonstrate (along with extrapolations from modeling) that the jet-merging process leads to Mach-number degradation and liner uniformity that are acceptable for MIF; and (3) conducting 4 π experiments with up to 60 guns to demonstrate the formation of an imploding spherical plasma liner for the first time, and to provide empirical ram-pressure and uniformity scaling data for benchmarking our codes and informing us whether the scalings justify further development beyond ALPHA. This talk will provide an overview of the PLX- α project as well as key research results to date. Supported by ARPA-E's ALPHA program; original PLX construction supported by DOE Fusion Energy Sciences.

  10. The Advanced Technology Large Aperture Space Telescope (ATLAST): Science Drivers and Technology Developments

    NASA Technical Reports Server (NTRS)

    Postman, Marc; Brown, Tom; Sembach, Kenneth; Giavalisco, Mauro; Traub, Wesley; Stapelfeldt, Karl; Calzetti, Daniela; Oegerle, William; Rich, R. Michael; Stahl, H. Phillip; hide

    2011-01-01

    The Advanced Technology Large-Aperture Space Telescope (ATLAST) is a concept for an 8-meter to 16-meter UVOIR space observatory for launch in the 2025-2030 era. ATLAST will allow astronomers to answer fundamental questions at the forefront of modern astrophysics, including "Is there life elsewhere in the Galaxy?" We present a range of science drivers and the resulting performance requirements for ATLAST (8 to 16 milliarcsecond angular resolution, diffraction limited imaging at 0.5 m wavelength, minimum collecting area of 45 square meters, high sensitivity to light wavelengths from 0.1 m to 2.4 m, high stability in wavefront sensing and control). We also discuss the priorities for technology development needed to enable the construction of ATLAST for a cost that is comparable to current generation observatory-class space missions. Keywords: Advanced Technology Large-Aperture Space Telescope (ATLAST); ultraviolet/optical space telescopes; astrophysics; astrobiology; technology development.

  11. Cost analysis of open radical cystectomy versus robot-assisted radical cystectomy.

    PubMed

    Bansal, Sukhchain S; Dogra, Tara; Smith, Peter W; Amran, Maisarah; Auluck, Ishna; Bhambra, Maninder; Sura, Manraj S; Rowe, Edward; Koupparis, Anthony

    2018-03-01

    To perform a cost analysis comparing the cost of robot-assisted radical cystectomy (RARC) with open RC (ORC) in a UK tertiary referral centre and to identify the key cost drivers. Data on hospital length of stay (LOS), operative time (OT), transfusion rate, and volume and complication rate were obtained from a prospectively updated institutional database for patients undergoing RARC or ORC. A cost decision tree model was created. Sensitivity analysis was performed to find key drivers of overall cost and to find breakeven points with ORC. Monte Carlo analysis was performed to quantify the variability in the dataset. One RARC procedure costs £12 449.87, or £12 106.12 if the robot was donated via charitable funds. In comparison, one ORC procedure costs £10 474.54. RARC is 18.9% more expensive than ORC. The key cost drivers were OT, LOS, and the number of cases performed per annum. High ongoing equipment costs remain a large barrier to the cost of RARC falling. However, minimal improvements in patient quality of life would be required to offset this difference. © 2017 The Authors BJU International © 2017 BJU International Published by John Wiley & Sons Ltd.

  12. Targeting key proximal drivers of type 2 inflammation in disease.

    PubMed

    Gandhi, Namita A; Bennett, Brandy L; Graham, Neil M H; Pirozzi, Gianluca; Stahl, Neil; Yancopoulos, George D

    2016-01-01

    Systemic type 2 inflammation encompassing T helper 2 (TH2)-type responses is emerging as a unifying feature of both classically defined allergic diseases, such as asthma, and a range of other inflammatory diseases. Rather than reducing inflammation with broad-acting immunosuppressants or narrowly targeting downstream products of the TH2 pathway, such as immunoglobulin E (IgE), efforts to target the key proximal type 2 cytokines - interleukin-4 (IL-4), IL-5 and IL-13 - represent a promising strategy to achieve therapeutic benefit across multiple diseases. After several initial disappointing clinical results with therapies targeting IL-4, IL-5 or IL-13 in asthma, applying a personalized approach achieved therapeutic benefit in an asthma subtype exhibiting an 'allergic' phenotype. More recently, efficacy was extended into a broad population of people with asthma. This argues that the Type 2 inflammation is broadly relevant across the severe asthma population if the key upstream drivers are properly blocked. Moreover, the simultaneous inhibition of IL-4 and IL-13 has shown significant clinical activity in diseases that are often co-morbid with asthma - atopic dermatitis and chronic sinusitis with nasal polyps - supporting the hypothesis that targeting a central 'driver pathway' could benefit multiple allergic diseases.

  13. Drivers of surface moisture flux variations in northern terrestrial regions

    NASA Astrophysics Data System (ADS)

    Fischer, R.; Walsh, J. E.

    2017-12-01

    The wetness of the high-latitude land surface is strongly dependent on the difference between precipitation (P) and evapotranspiration (ET). Variations of ET over daily, seasonal and interannual timescales are poorly documented, as are their relationships to key drivers. A combination of regional climate model output and eddy covariance measurements from five flux tower sites in Alaska are used to test the hypothesis that temperature is the key driver of ET in tundra regions underlain by permafrost, while precipitation plays a greater role in boreal forest areas. At the tundra sites, both the flux tower data and the model simulations show that daily and warm-season totals of ET are largely temperature driven, although daily ET also shows a negative correlation with P. At the boreal forest sites, P is the main driver of year-to-year variations of the seasonally integrated net moisture flux, although ET does not correlate strongly with either P or T. A short period of negative P-ET typically occurs during the warm season in the flux tower data. The model depicts a stronger hydrologic cycle (larger P, larger ET) relative to the measurements at all the sites.

  14. Strengthening the enabling environment for women and girls: what is the evidence in social and structural approaches in the HIV response?

    PubMed Central

    Hardee, Karen; Gay, Jill; Croce-Galis, Melanie; Peltz, Amelia

    2014-01-01

    There is growing interest in expanding public health approaches that address social and structural drivers that affect the environment in which behaviour occurs. Half of those living with HIV infection are women. The sociocultural and political environment in which women live can enable or inhibit their ability to protect themselves from acquiring HIV. This paper examines the evidence related to six key social and structural drivers of HIV for women: transforming gender norms; addressing violence against women; transforming legal norms to empower women; promoting women’s employment, income and livelihood opportunities; advancing education for girls and reducing stigma and discrimination. The paper reviews the evidence for successful and promising social and structural interventions related to each driver. This analysis contains peer-reviewed published research and study reports with clear and transparent data on the effectiveness of interventions. Structural interventions to address these key social and structural drivers have led to increasing HIV-protective behaviours, creating more gender-equitable relationships and decreasing violence, improving services for women, increasing widows’ ability to cope with HIV and reducing behaviour that increases HIV risk, particularly among young people. PMID:24405664

  15. Strengthening the enabling environment for women and girls: what is the evidence in social and structural approaches in the HIV response?

    PubMed

    Hardee, Karen; Gay, Jill; Croce-Galis, Melanie; Peltz, Amelia

    2014-01-01

    There is growing interest in expanding public health approaches that address social and structural drivers that affect the environment in which behaviour occurs. Half of those living with HIV infection are women. The sociocultural and political environment in which women live can enable or inhibit their ability to protect themselves from acquiring HIV. This paper examines the evidence related to six key social and structural drivers of HIV for women: transforming gender norms; addressing violence against women; transforming legal norms to empower women; promoting women's employment, income and livelihood opportunities; advancing education for girls and reducing stigma and discrimination. The paper reviews the evidence for successful and promising social and structural interventions related to each driver. This analysis contains peer-reviewed published research and study reports with clear and transparent data on the effectiveness of interventions. Structural interventions to address these key social and structural drivers have led to increasing HIV-protective behaviours, creating more gender-equitable relationships and decreasing violence, improving services for women, increasing widows' ability to cope with HIV and reducing behaviour that increases HIV risk, particularly among young people.

  16. 2009 Human Factors and Roadway Safety Workshop : Teen Driver Safety [SD .WMV (720x480/29fps/177.0 MB)

    DOT National Transportation Integrated Search

    2009-11-05

    Iowa Department of Transportation Research and Technology Bureau video presentation from the 2009 human factors and roadway safety workshop session titled: Teen Driver Safety : Keynote Speaker Dan McGehee, director, Human Factors & Vehicle Safety Res...

  17. Heavy vehicle driver workload assessment. Task 2, standard vehicle configuration/specifications

    DOT National Transportation Integrated Search

    A variety of high technology in-cab devices have been proposed for use in heavy trucks. Many of these devices introduce subsidiary tasks which may compete with the driver's primary task of safely controlling the vehicle at all times. As part of this ...

  18. The Global Rise of Zero Liquid Discharge for Wastewater Management: Drivers, Technologies, and Future Directions.

    PubMed

    Tong, Tiezheng; Elimelech, Menachem

    2016-07-05

    Zero liquid discharge (ZLD)-a wastewater management strategy that eliminates liquid waste and maximizes water usage efficiency - has attracted renewed interest worldwide in recent years. Although implementation of ZLD reduces water pollution and augments water supply, the technology is constrained by high cost and intensive energy consumption. In this critical review, we discuss the drivers, incentives, technologies, and environmental impacts of ZLD. Within this framework, the global applications of ZLD in the United States and emerging economies such as China and India are examined. We highlight the evolution of ZLD from thermal- to membrane-based processes, and analyze the advantages and limitations of existing and emerging ZLD technologies. The potential environmental impacts of ZLD, notably greenhouse gas emission and generation of solid waste, are discussed and the prospects of ZLD technologies and research needs are highlighted.

  19. Fifty years of driving safety research.

    PubMed

    Lee, John D

    2008-06-01

    This brief review covers the 50 years of driving-related research published in Human Factors, its contribution to driving safety, and emerging challenges. Many factors affect driving safety, making it difficult to assess the impact of specific factors such as driver age, cell phone distractions, or collision warnings. The author considers the research themes associated with the approximately 270 articles on driving published in Human Factors in the past 50 years. To a large extent, current and past research has explored similar themes and concepts. Many articles published in the first 25 years focused on issues such as driver impairment, individual differences, and perceptual limits. Articles published in the past 25 years address similar issues but also point toward vehicle technology that can exacerbate or mitigate the negative effect of these issues. Conceptual and computational models have played an important role in this research. Improved crash-worthiness has contributed to substantial improvements in driving safety over the past 50 years, but future improvements will depend on enhancing driver performance and perhaps, more important, improving driver behavior. Developing models to guide this research will become more challenging as new technology enters the vehicle and shifts the focus from driver performance to driver behavior. Over the past 50 years, Human Factors has accumulated a large base of driving-related research that remains relevant for many of today's design and policy concerns.

  20. Fatigue factors affecting metropolitan bus drivers: a qualitative investigation.

    PubMed

    Biggs, Herbert; Dingsdag, Donald; Stenson, Nick

    2009-01-01

    Metropolitan bus drivers daily face work in a stressful and draining work environment, exposing them to the serious risk of driver fatigue. However, there has been a dearth of information exploring the unique antecedents and effects of such fatigue. To date, much of the research into metropolitan bus drivers has been under the umbrella of large heavy vehicle driving studies, which include a disproportionally large population of long-haul drivers, who are likely to face a significantly different set of fatigue factors [1]. The present study aimed to investigate which work and environmental factors may cause fatigue in metropolitan bus drivers by seeking drivers' own perspectives on the issues. To this end, focus groups were held at five bus depots in Sydney and Newcastle, with an effort made to include a stratified sample of drivers at each. Each of the groups were invited to nominate what factors they felt were most salient, with a number of common factors emerging across the depots. Key themes identified were: support from management; ticketing and related issues; interaction with passengers; cabin ergonomics; tight route schedules; turn-around and shift irregularity; extended shift cycles; interactions with other road users; and extended commute times.

  1. Injury severity analysis of commercially-licensed drivers in single-vehicle crashes: Accounting for unobserved heterogeneity and age group differences.

    PubMed

    Osman, Mohamed; Mishra, Sabyasachee; Paleti, Rajesh

    2018-05-18

    This study analyzes the injury severity of commercially-licensed drivers involved in single-vehicle crashes. Considering the discrete ordinal nature of injury severity data, the ordered response modeling framework was adopted. The moderating effect of driver's age on all other factors was examined by segmenting the parameters by driver's age group. Additional effects of the different drivers' age groups are taken into consideration through interaction terms. Unobserved heterogeneity of the different covariates was investigated using the Mixed Generalized Ordered Response Probit (MGORP) model. The empirical analysis was conducted using four years of the Highway Safety Information System (HSIS) data that included 6247 commercially-licensed drivers involved in single-vehicle crashes in the state of Minnesota. The MGORP model elasticity effects indicate that key factors that increase the likelihood of severe crashes for commercially-licensed drivers across all age groups include: lack of seatbelt usage, collision with a fixed object, speeding, vehicle age of 11 years or more, wind, night time, weekday, and female drivers. Also, the effects of several covariates were found to vary across different age groups. Copyright © 2018 Elsevier Ltd. All rights reserved.

  2. Driver fatigue detection based on eye state.

    PubMed

    Lin, Lizong; Huang, Chao; Ni, Xiaopeng; Wang, Jiawen; Zhang, Hao; Li, Xiao; Qian, Zhiqin

    2015-01-01

    Nowadays, more and more traffic accidents occur because of driver fatigue. In order to reduce and prevent it, in this study, a calculation method using PERCLOS (percentage of eye closure time) parameter characteristics based on machine vision was developed. It determined whether a driver's eyes were in a fatigue state according to the PERCLOS value. The overall workflow solutions included face detection and tracking, detection and location of the human eye, human eye tracking, eye state recognition, and driver fatigue testing. The key aspects of the detection system incorporated the detection and location of human eyes and driver fatigue testing. The simplified method of measuring the PERCLOS value of the driver was to calculate the ratio of the eyes being open and closed with the total number of frames for a given period. If the eyes were closed more than the set threshold in the total number of frames, the system would alert the driver. Through many experiments, it was shown that besides the simple detection algorithm, the rapid computing speed, and the high detection and recognition accuracies of the system, the system was demonstrated to be in accord with the real-time requirements of a driver fatigue detection system.

  3. Prediction of destination entry and retrieval times using keystroke-level models

    DOT National Transportation Integrated Search

    1998-04-01

    Thirty-six drivers entered and retrieved destinations using an Ali-Scout navigation computer. Retrieval involved keying in part of the destination name, scrolling through a list of names, or a combination of those methods. Entry required keying in th...

  4. Evidence report : chronic kidney disease and commercial motor vehicle driver safety

    DOT National Transportation Integrated Search

    2007-11-05

    The purpose of this evidence report is to address several key questions posed by the Federal Motor Carrier Safety Administration (FMCSA). FMCSA developed each of these key questions so that the answers will provide information useful in updating its ...

  5. Cooperative Driver Education and Safety Training. Coordinator's Guide.

    ERIC Educational Resources Information Center

    Seyfarth, John T.; And Others

    Characteristics of the cooperative approach which give this program advantages of low-cost, high-quality, flexible driver-training accessible to more students are: (1) use of technological teaching aids, permitting large class enrollment; (2) shared operating costs and capital investment among cooperating schools or systems; (3) reduced capital…

  6. Transportation Energy Futures Series. Non-Cost Barriers to Consumer Adoption of New Light-Duty Vehicle Technologies

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stephens, Thomas

    2013-03-01

    Consumer preferences are key to the adoption of new vehicle technologies. Barriers to consumer adoption include price and other obstacles, such as limited driving range and charging infrastructure; unfamiliarity with the technology and uncertainty about direct benefits; limited makes and models with the technology; reputation or perception of the technology; standardization issues; and regulations. For each of these non-cost barriers, this report estimates an effective cost and summarizes underlying influences on consumer preferences, approximate magnitude and relative severity, and assesses potential actions, based on a comprehensive literature review. While the report concludes that non-cost barriers are significant, effective cost andmore » potential market share are very uncertain. Policies and programs including opportunities for drivers to test drive advanced vehicles, general public outreach and information programs, incentives for providing charging and fueling infrastructure, and development of technology standards were examined for their ability to address barriers, but little quantitative data exists on the effectiveness of these measures. This is one in a series of reports produced as a result of the Transportation Energy Futures project, a Department of Energy-sponsored multi-agency effort to pinpoint underexplored strategies for reducing GHGs and petroleum dependence related to transportation. View all reports on the TEF Web page, http://www.eere.energy.gov/analysis/transportationenergyfutures/index.html.« less

  7. Investigating Time-Varying Drivers of Grid Project Emissions Impacts

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Barrett, Emily L.; Thayer, Brandon L.; Pal, Seemita

    The emissions consequences of smart grid technologies depend heavily on their context and vary not only by geographical location, but by time of year. The same technology operated to meet the same objective may increase the emissions associated with energy generation for part of the year and decrease emissions during other times. The Grid Project Impact Quantification (GridPIQ) tool provides the ability to estimate these seasonal variations and garner insight into the time-varying drivers of grid project emissions impacts. This work leverages GridPIQ to examine the emissions implications across years and seasons of adding energy storage technology to reduce dailymore » peak demand in California and New York.« less

  8. Key cost drivers of pharmaceutical clinical trials in the United States.

    PubMed

    Sertkaya, Aylin; Wong, Hui-Hsing; Jessup, Amber; Beleche, Trinidad

    2016-04-01

    The increasing cost of clinical research has significant implications for public health, as it affects drug companies' willingness to undertake clinical trials, which in turn limits patient access to novel treatments. Thus, gaining a better understanding of the key cost drivers of clinical research in the United States is important. The study which is based on a report prepared by Eastern Research Group, Inc., for the US Department of Health and Human Services, examined different factors, such as therapeutic area, patient recruitment, administrative staff, and clinical procedure expenditures, and their contribution to pharmaceutical clinical trial costs in the United States by clinical trial phase. The study used aggregate data from three proprietary databases on clinical trial costs provided by Medidata Solutions. We evaluated per-study costs across therapeutic areas by aggregating detailed (per patient and per site) cost information. We also compared average expenditures on cost drivers with the use of weighted mean and standard deviation statistics. Therapeutic area was an important determinant of clinical trial costs by phase. The average cost of a Phase 1 study conducted at a US site ranged from US$1.4 million (pain and anesthesia) to US$6.6 million (immunomodulation), including estimated site overhead and monitoring costs of the sponsoring organization. A Phase 2 study cost from US$7.0 million (cardiovascular) to US$19.6 million (hematology), whereas a Phase 3 study cost ranged from US$11.5 million (dermatology) to US$52.9 (pain and anesthesia) on average. Across all study phases and excluding estimated site overhead costs and costs for sponsors to monitor the study, the top three cost drivers of clinical trial expenditures were clinical procedure costs (15%-22% of total), administrative staff costs (11%-29% of total), and site monitoring costs (9%-14% of total). The data were from 2004 through 2012 and were not adjusted for inflation. Additionally, the databases used represented a convenience, that is, non-probability, sample and did not allow for statistically valid estimates of cost drivers. Finally, the data were from trials funded by the global pharmaceutical and biotechnology industry only. Hence, our study findings are limited to that segment. Therapeutic area being studied as well as number and types of clinical procedures involved were the key drivers of direct costs in Phase 1 through Phase 3 studies. Research shows that strategies exist for reducing the price tag of some of these major direct cost components. Therefore, to increase clinical trial efficiency and reduce costs, gaining a better understanding of the key direct cost drivers is an important step. © The Author(s) 2016.

  9. Heritage and Advanced Technology Systems Engineering Lessons Learned from NASA Space Missions

    NASA Technical Reports Server (NTRS)

    Barley, Bryan; Newhouse, Marilyn; Bacskay, Allen

    2010-01-01

    Use of heritage and new technology is necessary/enabling to implementing small, low cost missions, yet overruns decrease the ability to sustain future mission flight rates The majority of the cost growth drivers seen in the D&NF study were embedded early during formulation phase and later realized during the development and I&T phases Cost drivers can be avoided or significantly decreased by project management and SE emphasis on early identification of risks and realistic analyses SE processes that emphasize an assessment of technology within the mission system to identify technical issues in the design or operational use of the technology. Realistic assessment of new and heritage spacecraft technology assumptions , identification of risks and mitigation strategies. Realistic estimates of effort required to inherit existing or qualify new technology, identification of risks to estimates and develop mitigation strategies. Allocation of project reserves for risk-based mitigation strategies of each individual area of heritage or new technology. Careful tailoring of inheritance processes to ensure due diligence.

  10. Evaluation of key driver categories influencing sustainable waste management development with the analytic hierarchy process (AHP): Serbia example.

    PubMed

    Tot, Bojana; Srđević, Bojan; Vujić, Bogdana; Russo, Mário Augusto Tavares; Vujić, Goran

    2016-08-01

    The problems of waste management have become increasingly complex in recent decades. The increasing amount of generated waste, adopted legislation in the field of waste management, administrative issues, economic impacts and social awareness are important drivers in achieving a sustainable waste management system. However, in practice, there are many other drivers that are often mutually in conflict. The purpose of this research is to define the precise driver and their corresponding sub-drivers, which are relevant for developing a waste management system and, on the basis of their importance, to determine which has the predominant influence on the slow development of a waste management system at the national and regional level, within the Republic of Serbia and similar countries of southeast Europe. This research presents two levels of decision making: the first is a pair-wise comparison of the drivers in relation to the goal and the second is a pair-wise comparison of the sub-drivers in relation to the driver and in relation to the goal. Results of performed analyses on the waste management drivers were integrated via the decision-making process supported by an analytic hierarchy process (AHP). The final results of this research shows that the Institutional-Administrative driver is the most important for developing a sustainable waste management system. © The Author(s) 2016.

  11. GPS Usage in a Population of Low-Vision Drivers.

    PubMed

    Cucuras, Maria; Chun, Robert; Lee, Patrick; Jay, Walter M; Pusateri, Gregg

    2017-01-01

    We surveyed bioptic and non-bioptic low-vision drivers in Illinois, USA, to determine their usage of global positioning system (GPS) devices. Low-vision patients completed an IRB-approved phone survey regarding driving demographics and usage of GPS while driving. Participants were required to be active drivers with an Illinois driver's license, and met one of the following criteria: best-corrected visual acuity (BCVA) less than or equal to 20/40, central or significant peripheral visual field defects, or a combination of both. Of 27 low-vision drivers, 10 (37%) used GPS while driving. The average age for GPS users was 54.3 and for non-users was 77.6. All 10 drivers who used GPS while driving reported increased comfort or safety level. Since non-GPS users were significantly older than GPS users, it is likely that older participants would benefit from GPS technology training from their low-vision eye care professionals.

  12. Developing and evaluating a mobile driver fatigue detection network based on electroencephalograph signals

    PubMed Central

    Yin, Jinghai; Mu, Zhendong

    2016-01-01

    The rapid development of driver fatigue detection technology indicates important significance of traffic safety. The authors’ main goals of this Letter are principally three: (i) A middleware architecture, defined as process unit (PU), which can communicate with personal electroencephalography (EEG) node (PEN) and cloud server (CS). The PU receives EEG signals from PEN, recognises the fatigue state of the driver, and transfer this information to CS. The CS sends notification messages to the surrounding vehicles. (ii) An android application for fatigue detection is built. The application can be used for the driver to detect the state of his/her fatigue based on EEG signals, and warn neighbourhood vehicles. (iii) The detection algorithm for driver fatigue is applied based on fuzzy entropy. The idea of 10-fold cross-validation and support vector machine are used for classified calculation. Experimental results show that the average accurate rate of detecting driver fatigue is about 95%, which implying that the algorithm is validity in detecting state of driver fatigue. PMID:28529761

  13. Developing and evaluating a mobile driver fatigue detection network based on electroencephalograph signals.

    PubMed

    Yin, Jinghai; Hu, Jianfeng; Mu, Zhendong

    2017-02-01

    The rapid development of driver fatigue detection technology indicates important significance of traffic safety. The authors' main goals of this Letter are principally three: (i) A middleware architecture, defined as process unit (PU), which can communicate with personal electroencephalography (EEG) node (PEN) and cloud server (CS). The PU receives EEG signals from PEN, recognises the fatigue state of the driver, and transfer this information to CS. The CS sends notification messages to the surrounding vehicles. (ii) An android application for fatigue detection is built. The application can be used for the driver to detect the state of his/her fatigue based on EEG signals, and warn neighbourhood vehicles. (iii) The detection algorithm for driver fatigue is applied based on fuzzy entropy. The idea of 10-fold cross-validation and support vector machine are used for classified calculation. Experimental results show that the average accurate rate of detecting driver fatigue is about 95%, which implying that the algorithm is validity in detecting state of driver fatigue.

  14. Future Regulations – A Catalyst for Technology Development

    EPA Science Inventory

    Summary of current mobile source regulations and EPA mobile source regulatory authority with an emphasis on how EPA regulations are a driver for the development and introduction of automotive technology.

  15. Can Link Analysis Be Applied to Identify Behavioral Patterns in Train Recorder Data?

    PubMed

    Strathie, Ailsa; Walker, Guy H

    2016-03-01

    A proof-of-concept analysis was conducted to establish whether link analysis could be applied to data from on-train recorders to detect patterns of behavior that could act as leading indicators of potential safety issues. On-train data recorders capture data about driving behavior on thousands of routine journeys every day and offer a source of untapped data that could be used to offer insights into human behavior. Data from 17 journeys undertaken by six drivers on the same route over a 16-hr period were analyzed using link analysis, and four key metrics were examined: number of links, network density, diameter, and sociometric status. The results established that link analysis can be usefully applied to data captured from on-vehicle recorders. The four metrics revealed key differences in normal driver behavior. These differences have promising construct validity as leading indicators. Link analysis is one method that could be usefully applied to exploit data routinely gathered by on-vehicle data recorders. It facilitates a proactive approach to safety based on leading indicators, offers a clearer understanding of what constitutes normal driving behavior, and identifies trends at the interface of people and systems, which is currently a key area of strategic risk. These research findings have direct applications in the field of transport data monitoring. They offer a means of automatically detecting patterns in driver behavior that could act as leading indicators of problems during operation and that could be used in the proactive monitoring of driver competence, risk management, and even infrastructure design. © 2015, Human Factors and Ergonomics Society.

  16. Factors associated with self-reported inattentive driving at highway-rail grade crossings.

    PubMed

    Zhao, Shanshan; Khattak, Aemal J

    2017-12-01

    This research identified factors associated with inattentive driving at Highway-Rail Grade Crossings (HRGCs) by investigating drivers' self-reported inattentive driving experiences and factors pertaining to their socioeconomic, personality, attitudinal, and other characteristics. A random selection of 2500 households in Nebraska received a survey questionnaire designed for licensed motor vehicle drivers; respondents returned 980 questionnaires. Factor analysis identified latent variables evaluating drivers' patience and inclination to wait for trains, attitudes toward new technology, law enforcement or education regarding HRGC safety, and the propensity to commit serious traffic violations at HRGCs. The investigation utilized a structural equation model for analysis. This model indicated that drivers with a higher risk of inattentive driving at HRGCs were: female, younger in age, from households with higher incomes, with shorter tenure (in years) in their current city of residence, more frequently used HRGCs, received less information on safety at HRGCs, had less patience to wait for trains to pass and had less interest in safety improvement technology, law enforcement or safety education at HRGCs. These research findings provide useful information for future research and to policy makers for improving public safety. Additionally, the results are useful for safety educational program providers for targeted program delivery to drivers that are more vulnerable to distracted driving at HRGCs. Copyright © 2017 Elsevier Ltd. All rights reserved.

  17. Key Reliability Drivers of Liquid Propulsion Engines and A Reliability Model for Sensitivity Analysis

    NASA Technical Reports Server (NTRS)

    Huang, Zhao-Feng; Fint, Jeffry A.; Kuck, Frederick M.

    2005-01-01

    This paper is to address the in-flight reliability of a liquid propulsion engine system for a launch vehicle. We first establish a comprehensive list of system and sub-system reliability drivers for any liquid propulsion engine system. We then build a reliability model to parametrically analyze the impact of some reliability parameters. We present sensitivity analysis results for a selected subset of the key reliability drivers using the model. Reliability drivers identified include: number of engines for the liquid propulsion stage, single engine total reliability, engine operation duration, engine thrust size, reusability, engine de-rating or up-rating, engine-out design (including engine-out switching reliability, catastrophic fraction, preventable failure fraction, unnecessary shutdown fraction), propellant specific hazards, engine start and cutoff transient hazards, engine combustion cycles, vehicle and engine interface and interaction hazards, engine health management system, engine modification, engine ground start hold down with launch commit criteria, engine altitude start (1 in. start), Multiple altitude restart (less than 1 restart), component, subsystem and system design, manufacturing/ground operation support/pre and post flight check outs and inspection, extensiveness of the development program. We present some sensitivity analysis results for the following subset of the drivers: number of engines for the propulsion stage, single engine total reliability, engine operation duration, engine de-rating or up-rating requirements, engine-out design, catastrophic fraction, preventable failure fraction, unnecessary shutdown fraction, and engine health management system implementation (basic redlines and more advanced health management systems).

  18. Finding the Value of Urban Parking : An Analysis of the Impacts of Smart Parking Systems on Congestion and Land Values in Downtown Houston, Final Report

    DOT National Transportation Integrated Search

    2018-01-01

    For this report, researchers have examined smart parking, which is a parking management tool that uses various technologies to aid drivers in efficiently locating and paying for available parking. Smart parking systems allow drivers to know where the...

  19. A Review of the Environmental Impacts for Marine and Hydrokinetic Projects to Inform Regulatory Permitting: Summary Findings from the 2015 Workshop on Marine and Hydrokinetic Technologies, Washington, D.C.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Baring-Gould, E. Ian; Christol, Corrie; LiVecchi, Al

    In 2014 and 2015, the U.S. Department of Energy initiated efforts to develop and implement technology- and application-focused marine and hydrokinetic (MHK) workshops to share the global experience and knowledge base on evolving MHK technologies, observed and not-observed impacts, monitoring and measurement methods, and regulatory needs. The resulting MHK Regulator Workshops engaged resource managers and other decision makers at key regulatory organizations, scientists, researchers, facilitators, and technical experts and provided an opportunity to examine the risks of single-device and small-scale deployments, explore what can be learned and observed from single devices and small-scale arrays, and consider requirements for projects atmore » varying scales of deployment. Experts and stakeholders identified key remaining information gaps. Initial discussions focused on differentiating between monitoring required for single or small-scale deployments and MHK impact research that, although important, goes beyond what is feasible or should be needed to meet specific project regulatory requirements but is appropriate for broader research and development. Four areas of identified potential environmental impacts provided the focus for the workshop: acoustic output impacts, electromagnetic field (EMF) emissions, physical interactions, and environmental effects of MHK energy development on the physical environment. Discussions also focused on the regulatory process and experience, adaptive management, industry drivers, and lessons that can be learned from the wind energy industry. The discussion was set in the context of the types of MHK technologies that are currently proposed or planned in the United States. All presentations and the following discussions are summarized in this document.« less

  20. Microsimulation of household and firm behaviors : coupled models of land use and travel demand in Austin, Texas

    DOT National Transportation Integrated Search

    2007-12-01

    Households and firms are key drivers of urban growth, yet models for forecasting travel demand often : ignore their dynamic evolution and several key decision processes. An understanding of household and : firm behavior over time is critical in antic...

  1. Initial Results of Accelerated Stress Testing on Single-Channel and Multichannel Drivers: Solid-State Lighting Technology Area

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    This report is the first in a series of studies on accelerated stress testing (AST) of drivers used for SSL luminaires, such as downlights, troffers, and streetlights. A representative group of two-stage commercial driver products was exposed to an AST environment consisting of 75°C and 75% relative humidity (7575). These drivers were a mix of single-channel drivers (i.e., a single output current for one LED primary) and multichannel drivers (i.e., separate output currents for multiple LED primaries). This AST environment was chosen because previous testing on downlights with integrated drivers demonstrated that 38% of the sample population failed in lessmore » than 2,500 hours of testing using this method. In addition to AST test results, the performance of an SSL downlight product incorporating an integrated, multichannel driver during extended room temperature operational life (RTOL) testing is also reported. A battery of measurements was used to evaluate these products during accelerated testing, including full electrical characterization (i.e., power consumption, PF, total harmonic distortion [THD], and inrush current) and photometric characterization of external LED loads attached to the drivers (i.e., flicker performance and lumen maintenance).« less

  2. Wireless Roadside Inspection Proof of Concept Test Final Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Capps, Gary J; Franzese, Oscar; Knee, Helmut E

    2009-03-01

    The U.S. Department of Transportation (DOT) FMCSA commissioned the Wireless Roadside Inspection (WRI) Program to validate technologies and methodologies that can improve safety through inspections using wireless technologies that convey real-time identification of commercial vehicles, drivers, and carriers, as well as information about the condition of the vehicles and their drivers. It is hypothesized that these inspections will: -- Increase safety -- Decrease the number of unsafe commercial vehicles on the road; -- Increase efficiency -- Speed up the inspection process, enabling more inspections to occur, at least on par with the number of weight inspections; -- Improve effectiveness --more » Reduce the probability of drivers bypassing CMV inspection stations and increase the likelihood that fleets will attempt to meet the safety regulations; and -- Benefit industry -- Reduce fleet costs, provide good return-on-investment, minimize wait times, and level the playing field. The WRI Program is defined in three phases which are: Phase 1: Proof of Concept Test (POC) Testing of commercially available off-the-shelf (COTS) or near-COTS technology to validate the wireless inspection concept. Phase 2: Pilot Test Safety technology maturation and back office system integration Phase 3: Field Operational Test Multi-vehicle testing over a multi-state instrumented corridor This report focuses on Phase 1 efforts that were initiated in March, 2006. Technical efforts dealt with the ability of a Universal Wireless Inspection System (UWIS) to collect driver, vehicle, and carrier information; format a Safety Data Message Set from this information; and wirelessly transmit a Safety Data Message Set to a roadside receiver unit or mobile enforcement vehicle.« less

  3. Evaluation of moving-coil loudspeaker and passive radiator parameters using normal-incidence sound transmission measurements: theoretical developments.

    PubMed

    Leishman, Timothy W; Anderson, Brian E

    2013-07-01

    The parameters of moving-coil loudspeaker drivers are typically determined using direct electrical excitation and measurement. However, as electro-mechano-acoustical devices, their parameters should also follow from suitable mechanical or acoustical evaluations. This paper presents the theory of an acoustical method of excitation and measurement using normal-incidence sound transmission through a baffled driver as a plane-wave tube partition. Analogous circuits enable key parameters to be extracted from measurement results in terms of open and closed-circuit driver conditions. Associated tools are presented that facilitate adjacent field decompositions and derivations of sound transmission coefficients (in terms of driver parameters) directly from the circuits. The paper also clarifies the impact of nonanechoic receiving tube terminations and the specific benefits of downstream field decompositions.

  4. The Ariane Transfer Vehicle (ATV) system studies

    NASA Astrophysics Data System (ADS)

    Thomas, U.; Thirkettle, A.

    1991-08-01

    Two distinct concepts of the Ariane transfer vehicle (ATV) are compared which incorporate existing ATV technology and offer logistics delivery at competitive costs. One concept is based on the Ariane-5 upper stage and the Vehicle Equipment Bay, and the other does not include Ariane-5 functions so that existing upper-stage limitations can be eliminated. Both concepts are required to accomplish the same transport, rendezvous, and berthing maneuvers and allow for controlled destructive reentry. An ATV reference mission is outlined, and key ATV design drivers are listed which include safety requirements, debris protection, and propulsion criteria. The Ariane-5 upgrade is the most cost-effective design although the second design is more operationally efficient. The ATV can potentially be used to relieve the schedule of the shuttle flights required for building the Space Station Freedom.

  5. Online performance evaluation of RAID 5 using CPU utilization

    NASA Astrophysics Data System (ADS)

    Jin, Hai; Yang, Hua; Zhang, Jiangling

    1998-09-01

    Redundant arrays of independent disks (RAID) technology is the efficient way to solve the bottleneck problem between CPU processing ability and I/O subsystem. For the system point of view, the most important metric of on line performance is the utilization of CPU. This paper first employs the way to calculate the CPU utilization of system connected with RAID level 5 using statistic average method. From the simulation results of CPU utilization of system connected with RAID level 5 subsystem can we see that using multiple disks as an array to access data in parallel is the efficient way to enhance the on-line performance of disk storage system. USing high-end disk drivers to compose the disk array is the key to enhance the on-line performance of system.

  6. Transforming a Liability Into An Asset-Creating a Market for CO2-based Products

    NASA Astrophysics Data System (ADS)

    David, B. J.

    2016-12-01

    This session will discuss converting CO2 from a liability into an asset. It will specifically discuss how at least 25 products can be created using CO2 as a feedstock and deployed in the market at large scale. Focus will be on products that can both achieve scale from a market standpoint as well as climate significance in use of CO2 as a feedstock. The session will describe the market drivers supporting and inhibiting commercial deployment of CO2-based products. It will list key barriers and risks in the various CO2-based product segments. These barriers/risks could occur across technology, policy, institutional, economic, and other dimensions. The means to mitigate each barrier and the likelihood for such means to be deployed will be discussed.

  7. Refuse and the ‘Risk Society’: The Political Ecology of Risk in Inter-war Britain

    PubMed Central

    Cooper, Timothy; Bulmer, Sarah

    2013-01-01

    This article responds to current critiques of Ulrich Beck's ‘risk society’ thesis by historians of science and medicine. Those who have engaged with the concept of risk society have been content to accept the fundamental categories of Beck's analysis. In contrast, we argue that Beck's risk society thesis underplays two key themes. First, the role of capitalist social relations as the driver of technological change and the transformation of everyday life; and second, the ways in which hegemonic discourses of risk can be appropriated and transformed by counter-hegemonic forces. In place of ‘risk society’, we propose an approach based upon a ‘political ecology of risk’, which emphasises the social relations that are fundamental to the everyday politics of environmental health. PMID:24771975

  8. Electronics drivers for high voltage dielectric electro active polymer (DEAP) applications

    NASA Astrophysics Data System (ADS)

    Zhang, Zhe; Andersen, Michael A. E.

    2015-04-01

    Dielectric electro active polymer (DEAP) can be used in actuation, sensing and energy harvesting applications, but driving the DEAP based actuators and generators has three main challenges from a power electronics standpoint, i.e. high voltage (around 2.5 kV), nonlinearity, and capacitive behavior. In this paper, electronics divers for heating valves, loud speakers, incremental motors, and energy harvesting are reviewed, studied and developed in accordance with their corresponding specifications. Due to the simplicity and low power capacity (below 10W), the reversible Fly-back converters with both magnetic and piezoelectric transformers are employed for the heating valve and incremental motor application, where only ON/OFF regulation is adopted for energy saving; as for DEAP based energy harvesting, the noisolated Buck/Boost converter is used, due to the system high power capacity (above 100W), but the voltage balancing across the series-connected high voltage IGBTs is a critical issue and accordingly a novel gate driver circuitry is proposed and equipped; due to the requirements of the audio products, such as low distortion and noise, the multi-level Buck converter based Class-D amplifier, because of its high control linearity, is implemented for the loud speaker applications. A synthesis among those converter topologies and control techniques is given; therefore, for those DEAP based applications, their diversity and similarity of electronics drivers, as well as the key technologies employed are analyzed. Therefore a whole picture of how to choose the proper topologies can be revealed. Finally, the design guidelines in order to achieve high efficiency and reliability are discussed.

  9. Commercial Motor Vehicle Driver Obstructive Sleep Apnea Screening and Treatment in the United States: An Update and Recommendation Overview.

    PubMed

    Colvin, Loretta J; Collop, Nancy A

    2016-01-01

    No regulatory mandate exists in the United States (U.S.) for comprehensive obstructive sleep apnea (OSA) risk assessment and stratification for commercial motor vehicle (CMV) drivers. Current Federal Motor Carrier Safety Administration (FMCSA) requirements are outdated and depend largely on subjective report, a less reliable strategy in an occupational setting. Without FMCSA standards, sleep specialists, occupational medical examiners and employers rely on a collection of medical consensus recommendations to establish standards of care. These recommendations advise OSA risk assessment through a combination of focused medical history, physical examination, questionnaires, and accident history, which increase OSA detection compared to current FMCSA standards. For those diagnosed with OSA, consensus-based risk stratification helps identify CMV drivers who may benefit from OSA treatment and establish minimum standards for assessing treatment efficacy and adherence. Unfortunately no consolidated recommendation exists; rather, publications span medical and governmental literature in a patchwork fashion that no longer fully reflect current practice due to subsequent advances in OSA diagnosis, treatment, and technology. Based on searches of medical literature, internet materials, and reference lists from existing publications, an overview and discussion of key published recommendations regarding OSA assessment and treatment in CMV operators is provided. Suggestions for incorporating these recommendations into clinical sleep medicine practice in the U.S. are presented. The challenge for sleep specialists is maintaining the delicate balance between recommendations impacting standard of care and associated medico-legal impact with stakeholder interests from medical, regulatory, industry and public perspectives while providing high quality and efficient care. © 2016 American Academy of Sleep Medicine.

  10. Driver ASIC Environmental Testing and Performance Optimization for SpaceBased Active Mirrors

    NASA Astrophysics Data System (ADS)

    Mejia Prada, Camilo

    Direct imaging of Earth-like planets requires techniques for light suppression, such as coronagraphs or nulling interferometers, in which deformable mirrors (DM) are a principal component. On ground-based systems, DMs are used to correct for turbulence in the Earth’s atmosphere in addition to static aberrations in the optics. For space-based observations, DMs are used to correct for static and quasi- static aberrations in the optical train. State-of-the-art, high-actuator count deformable mirrors suffer from external heavy and bulky electronics in which electrical connections are made through thousands of wires. We are instead developing Application Specific Integrated Circuits (ASICs) capable of direct integration with the DM in a single small package. This integrated ASIC-DM is ideal for space missions, where it offers significant reduction in mass, power and complexity, and performance compatible with high-contrast observations of exoplanets. We have successfully prototyped and tested a 32x32 format Switch-Mode (SM) ASIC which consumes only 2mW static power (total, not per-actuator). A number of constraints were imposed on key parameters of this ASIC design, including sub-picoamp levels of leakage across turned-off switches and from switch-to-substrate, control resolution of 0.04 mV, satisfactory rise/fall times, and a near-zero on-chip crosstalk over a useful range of operating temperatures. This driver ASIC technology is currently at TRL 4. This Supporting Technology proposal will further develop the ASIC technology to TRL 5 by carrying on environmental tests and further optimizing performance, with the end goal of making ASICs suitable for space-based deployment. The effort will be led by JPL, which has considerable expertise with DMs used in highcontrast imaging systems for exoplanet missions and in adaptive optic systems, and in design of DM driver electronics. Microscale, which developed the prototype of the ASICDM, will continue its development. We propose a three-part program to advance the device maturity. The effort will cover (1) radiation hardness, (2) thermal-vacuum environment tests, and (3) parameter performance optimization. We expect to implement the results in an optimized ASIC design for NASA's space applications, expanding the current state-of-the-art into radiation-hardened electronics robust enough for a space environment. This effort will fill technology gaps listed in the Exoplanet Exploration Program Technology Plan 2017 : “The challenge is believed to not be the mosaicking of 48×48 devices or 32×32 devices (to reach 128×128) but rather dealing with the enormous number of interconnects and their electronics.”. After the close of this effort, continued ASIC development is of course planned, leading to further improvement in parameters.

  11. Driver's behavioural changes with new intelligent transport system interventions at railway level crossings--A driving simulator study.

    PubMed

    Larue, Grégoire S; Kim, Inhi; Rakotonirainy, Andry; Haworth, Narelle L; Ferreira, Luis

    2015-08-01

    Improving safety at railway level crossings is an important issue for the Australian transport system. Governments, the rail industry and road organisations have tried a variety of countermeasures for many years to improve railway level crossing safety. New types of intelligent transport system (ITS) interventions are now emerging due to the availability and the affordability of technology. These interventions target both actively and passively protected railway level crossings and attempt to address drivers' errors at railway crossings, which are mainly a failure to detect the crossing or the train and misjudgement of the train approach speed and distance. This study aims to assess the effectiveness of three emerging ITS that the rail industry considers implementing in Australia: a visual in-vehicle ITS, an audio in-vehicle ITS, as well as an on-road flashing beacons intervention. The evaluation was conducted on an advanced driving simulator with 20 participants per trialled technology, each participant driving once without any technology and once with one of the ITS interventions. Every participant drove through a range of active and passive crossings with and without trains approaching. Their speed approach of the crossing, head movements and stopping compliance were measured. Results showed that driver behaviour was changed with the three ITS interventions at passive crossings, while limited effects were found at active crossings, even with reduced visibility. The on-road intervention trialled was unsuccessful in improving driver behaviour; the audio and visual ITS improved driver behaviour when a train was approaching. A trend toward worsening driver behaviour with the visual ITS was observed when no trains were approaching. This trend was not observed for the audio ITS intervention, which appears to be the ITS intervention with the highest potential for improving safety at passive crossings. Copyright © 2015 Elsevier Ltd. All rights reserved.

  12. Associating crash avoidance maneuvers with driver attributes and accident characteristics: a mixed logit model approach.

    PubMed

    Kaplan, Sigal; Prato, Carlo Giacomo

    2012-01-01

    The current study focuses on the propensity of drivers to engage in crash avoidance maneuvers in relation to driver attributes, critical events, crash characteristics, vehicles involved, road characteristics, and environmental conditions. The importance of avoidance maneuvers derives from the key role of proactive and state-aware road users within the concept of sustainable safety systems, as well as from the key role of effective corrective maneuvers in the success of automated in-vehicle warning and driver assistance systems. The analysis is conducted by means of a mixed logit model that represents the selection among 5 emergency lateral and speed control maneuvers (i.e., "no avoidance maneuvers," "braking," "steering," "braking and steering," and "other maneuvers) while accommodating correlations across maneuvers and heteroscedasticity. Data for the analysis were retrieved from the General Estimates System (GES) crash database for the year 2009 by considering drivers for which crash avoidance maneuvers are known. The results show that (1) the nature of the critical event that made the crash imminent greatly influences the choice of crash avoidance maneuvers, (2) women and elderly have a relatively lower propensity to conduct crash avoidance maneuvers, (3) drowsiness and fatigue have a greater negative marginal effect on the tendency to engage in crash avoidance maneuvers than alcohol and drug consumption, (4) difficult road conditions increase the propensity to perform crash avoidance maneuvers, and (5) visual obstruction and artificial illumination decrease the probability to carry out crash avoidance maneuvers. The results emphasize the need for public awareness campaigns to promote safe driving style for senior drivers and warning about the risks of driving under fatigue and distraction being comparable to the risks of driving under the influence of alcohol and drugs. Moreover, the results suggest the need to educate drivers about hazard perception, designing a forgiving infrastructure within a sustainable safety systems, and rethinking in-vehicle collision warning systems. Future research should address the effectiveness of crash avoidance maneuvers and joint modeling of maneuver selection and crash severity.

  13. Energy conservation and efficiency in manufacturing: Employee decisions and actions

    NASA Astrophysics Data System (ADS)

    Corson, Marla D.

    Energy conservation and intensity reduction efforts are becoming increasingly more prevalent and ultimately necessary, especially for energy-intensive manufacturing companies in particular to stay in business. Typical actions are to change technology, and thus, realize an energy cost savings in overall utilities. However, in today's competitive market, with climate change and other environmental impacts as well, it is necessary for the cost of energy to be valued as a cost of making a product, and thus, managed at the same level as the cost of labor or materials. This research assessed human behavior at the individual and organizational levels both at work and at home that either prompted or prohibited employees from taking daily action to conserve energy or develop greater energy efficient practices. Ultimately, the questions began with questions regarding employee views and knowledge of energy at work and at home and what drives both behaviors toward conservation or efficiency. And, the contribution identifies the key drivers, barriers, and/or incentives that affect those behaviors. The results of this study show that the key driver and motivator for energy conservation both at home and work is cost savings. The study showed that to further motivate individuals to conserve energy at home and work, more knowledge of the impact their actions have or could have as well as tools would be needed. The most poinient aspect of the research was the level of importance placed on energy conservation and the desire to conserve. The feedback given to the open ended questions was quite impressive regarding what employees have done and continue to do particularly within their homes to conserve energy. These findings brought about final recommendations that were in fact not expected but could significantly influence an increase in energy conservation at work by leveraging the existing desire to conserve which is a key component to decision making.

  14. Optical/digital identification/verification system based on digital watermarking technology

    NASA Astrophysics Data System (ADS)

    Herrigel, Alexander; Voloshynovskiy, Sviatoslav V.; Hrytskiv, Zenon D.

    2000-06-01

    This paper presents a new approach for the secure integrity verification of driver licenses, passports or other analogue identification documents. The system embeds (detects) the reference number of the identification document with the DCT watermark technology in (from) the owner photo of the identification document holder. During verification the reference number is extracted and compared with the reference number printed in the identification document. The approach combines optical and digital image processing techniques. The detection system must be able to scan an analogue driver license or passport, convert the image of this document into a digital representation and then apply the watermark verification algorithm to check the payload of the embedded watermark. If the payload of the watermark is identical with the printed visual reference number of the issuer, the verification was successful and the passport or driver license has not been modified. This approach constitutes a new class of application for the watermark technology, which was originally targeted for the copyright protection of digital multimedia data. The presented approach substantially increases the security of the analogue identification documents applied in many European countries.

  15. Driver-centred vehicle automation: using network analysis for agent-based modelling of the driver in highly automated driving systems.

    PubMed

    Banks, Victoria A; Stanton, Neville A

    2016-11-01

    To the average driver, the concept of automation in driving infers that they can become completely 'hands and feet free'. This is a common misconception, however, one that has been shown through the application of Network Analysis to new Cruise Assist technologies that may feature on our roads by 2020. Through the adoption of a Systems Theoretic approach, this paper introduces the concept of driver-initiated automation which reflects the role of the driver in highly automated driving systems. Using a combination of traditional task analysis and the application of quantitative network metrics, this agent-based modelling paper shows how the role of the driver remains an integral part of the driving system implicating the need for designers to ensure they are provided with the tools necessary to remain actively in-the-loop despite giving increasing opportunities to delegate their control to the automated subsystems. Practitioner Summary: This paper describes and analyses a driver-initiated command and control system of automation using representations afforded by task and social networks to understand how drivers remain actively involved in the task. A network analysis of different driver commands suggests that such a strategy does maintain the driver in the control loop.

  16. A Multifaceted Approach to Improving Outcomes in the NICU: The Pediatrix 100 000 Babies Campaign.

    PubMed

    Ellsbury, Dan L; Clark, Reese H; Ursprung, Robert; Handler, Darren L; Dodd, Elizabeth D; Spitzer, Alan R

    2016-04-01

    Despite advances in neonatal medicine, infants requiring neonatal intensive care continue to experience substantial morbidity and mortality. The purpose of this initiative was to generate large-scale simultaneous improvements in multiple domains of care in a large neonatal network through a program called the "100,000 Babies Campaign." Key drivers of neonatal morbidity and mortality were identified. A system for retrospective morbidity and mortality review was used to identify problem areas for project prioritization. NICU system analysis and staff surveys were used to facilitate reengineering of NICU systems in 5 key driver areas. Electronic health record-based automated data collection and reporting were used. A quality improvement infrastructure using the Kotter organizational change model was developed to support the program. From 2007 to 2013, data on 422 877 infants, including a subset with birth weight of 501 to 1500 g (n = 58 555) were analyzed. Key driver processes (human milk feeding, medication use, ventilator days, admission temperature) all improved (P < .0001). Mortality, necrotizing enterocolitis, retinopathy of prematurity, bacteremia after 3 days of life, and catheter-associated infection decreased. Survival without significant morbidity (necrotizing enterocolitis, severe intraventricular hemorrhage, severe retinopathy of prematurity, oxygen use at 36 weeks' gestation) improved. Implementation of a multifaceted quality improvement program that incorporated organizational change theory and automated electronic health record-based data collection and reporting program resulted in major simultaneous improvements in key neonatal processes and outcomes. Copyright © 2016 by the American Academy of Pediatrics.

  17. Review of Technology to Prevent Alcohol-Impaired Crashes (TOPIC)

    DOT National Transportation Integrated Search

    2007-07-01

    This report summarizes the results of an evaluation of vehicular technology alternatives to detect driver blood alcohol concentration and alcohol- : impaired driving. Taking an international perspective, this report references relevant literature, in...

  18. The Integrity bare-metal stent made by continuous sinusoid technology.

    PubMed

    Turco, Mark A

    2011-05-01

    The Integrity Coronary Stent System (Medtronic Vascular, CA, USA) is a low-profile, open-cell, cobalt-chromium-alloy advanced bare-metal iteration of the well-known Driver/Micro-Driver Coronary Stent System (Medtronic Vascular). The Integrity stent is made with a process called continuous sinusoid technology. This process allows stent construction via wrapping a single thin strand of wire around a mandrel in a sinusoid configuration, with laser fusion of adjacent crowns. The wire-forming process and fusion pattern provide the stent with a continuous preferential bending plane, intended to allow easier access to, and smoother tracking within, distal and tortuous vessels while radial strength is maintained. Continuous sinusoid technology represents innovation in the design of stent platforms and will provide a future stent platform for newer technology, including drug-eluting stent platforms, drug-filled stents and core wire stents.

  19. Advanced Technology Large-Aperture Space Telescope: Science Drivers and Technology Developments

    NASA Technical Reports Server (NTRS)

    Postman, Marc; Brown, Tom; Sembach, Kenneth; Glavallsco, Mauro; Traub, Wesley; Stapelfeldt, Karl; Calzetti, Daniela; Oegerle, William; Rich, R. Michael; Stahl, H. Philip; hide

    2012-01-01

    The Advanced Technology Large-Aperture Space Telescope (ATLAST) is a concept for an 8- to 16-m ultraviolet optical near Infrared space observatory for launch in the 2025 to 2030 era. ATLAST will allow astronomers to answer fundamental questions at the forefront of modern astrophysics, including: Is there life elsewhere in the Galaxy? We present a range of science drivers and the resulting performance requirements for ATLAST (8- to 16-marcsec angular resolution, diffraction limited imaging at 0.5 micron wavelength, minimum collecting area of 45 sq m, high sensitivity to light wavelengths from 0.1 to 2.4 micron, high stability in wavefront sensing and control). We also discuss the priorities for technology development needed to enable the construction of ATLAST for a cost that is comparable to that of current generation observatory-class space missions.

  20. Assessing contextual factors that influence acceptance of pedestrian alerts by a night vision system.

    PubMed

    Källhammer, Jan-Erik; Smith, Kip

    2012-08-01

    We investigated five contextual variables that we hypothesized would influence driver acceptance of alerts to pedestrians issued by a night vision active safety system to inform the specification of the system's alerting strategies. Driver acceptance of automotive active safety systems is a key factor to promote their use and implies a need to assess factors influencing driver acceptance. In a field operational test, 10 drivers drove instrumented vehicles equipped with a preproduction night vision system with pedestrian detection software. In a follow-up experiment, the 10 drivers and 25 additional volunteers without experience with the system watched 57 clips with pedestrian encounters gathered during the field operational test. They rated the acceptance of an alert to each pedestrian encounter. Levels of rating concordance were significant between drivers who experienced the encounters and participants who did not. Two contextual variables, pedestrian location and motion, were found to influence ratings. Alerts were more accepted when pedestrians were close to or moving toward the vehicle's path. The study demonstrates the utility of using subjective driver acceptance ratings to inform the design of active safety systems and to leverage expensive field operational test data within the confines of the laboratory. The design of alerting strategies for active safety systems needs to heed the driver's contextual sensitivity to issued alerts.

  1. The Nature of the Beast and the Beast in Nature: Broadening the Perspective of Technology

    ERIC Educational Resources Information Center

    Ruth, Matthias

    2009-01-01

    This article traces conceptualizations of technology from narrow definitions to a broader understanding that encompasses the larger social and environmental context within which technology operates. In doing so, the associated social and environmental drivers and impacts of technology are identified and conclusions are drawn for the roles of…

  2. Future Work. Myths and Realities No. 11.

    ERIC Educational Resources Information Center

    Kerka, Sandra

    In many of the stories foretelling the future of work, technology is assumed to be the irresistible driver of change. Both ends of the spectrum are foreseen: either technology will create new jobs and transform existing work to higher skill levels, or technology, especially information technology, will destroy jobs or degrade them into less…

  3. Scoping the parameter space for demo and the engineering test facility (ETF)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Meier, Wayne R.

    1999-01-19

    In our IFE development plan, we have set a goal of building an Engineering Test Facility (ETF) for a total cost of $2B and a Demo for $3B. In Mike Campbell' s presentation at Madison, we included a viewgraph with an example Demo that had 80 to 250 MWe of net power and showed a plausible argument that it could cost less than $3B. In this memo, I examine the design space for the Demo and then briefly for the ETF. Instead of attempting to estimate the costs of the drivers, I pose the question in a way to definemore » R&D goals: As a function of key design and performance parameters, how much can the driver cost if the total facility cost is limited to the specified goal? The design parameters examined for the Demo included target gain, driver energy, driver efficiency, and net power output. For the ETF; the design parameters are target gain, driver energy, and target yield. The resulting graphs of allowable driver cost determine the goals that the driver R&D programs must seek to meet.« less

  4. A National Evaluation of the Nighttime and Passenger Restriction Components of Graduated Driver Licensing

    PubMed Central

    Fell, James C.; Todd, Michael; Voas, Robert B.

    2011-01-01

    Introduction The high crash rate of youthful novice drivers has been recognized for half a century. Over the last decade, graduated driver licensing (GDL) systems, which extend the period of supervised driving and limit the novice’s exposure to higher-risk conditions (such as nighttime driving) has effectively reduced crash involvements of novice drivers. Method This study used data from the Fatality Analysis Reporting System (FARS) and the implementation dates of GDL laws in a state-by-year panel study to evaluate the effectiveness of two key elements of GDL laws: nighttime restrictions and passenger limitations. Results Nighttime restrictions were found to reduce 16- and 17-year-old driver involvements in nighttime fatal crashes by an estimated 10% and 16- and 17-year-old drinking drivers in nighttime fatal crashes by 13%. Passenger restrictions were found to reduce 16- and 17-year-old driver involvements in fatal crashes with teen passengers by an estimated 9%. Conclusions These results confirm the effectiveness of these provisions in GDL systems. Impact on Public Health The results of this study indicate that nighttime restrictions and passenger limitations are very important components of any GDL law. PMID:22017831

  5. Drivers and applications of integrated clean-up technologies for surfactant-enhanced remediation of environments contaminated with polycyclic aromatic hydrocarbons (PAHs).

    PubMed

    Liang, Xujun; Guo, Chuling; Liao, Changjun; Liu, Shasha; Wick, Lukas Y; Peng, Dan; Yi, Xiaoyun; Lu, Guining; Yin, Hua; Lin, Zhang; Dang, Zhi

    2017-06-01

    Surfactant-enhanced remediation (SER) is considered as a promising and efficient remediation approach. This review summarizes and discusses main drivers on the application of SER in removing polycyclic aromatic hydrocarbons (PAHs) from contaminated soil and water. The effect of PAH-PAH interactions on SER efficiency is, for the first time, illustrated in an SER review. Interactions between mixed PAHs could enhance, decrease, or have no impact on surfactants' solubilization power towards PAHs, thus affecting the optimal usage of surfactants for SER. Although SER can transfer PAHs from soil/non-aqueous phase liquids to the aqueous phase, the harmful impact of PAHs still exists. To decrease the level of PAHs in SER solutions, a series of SER-based integrated cleanup technologies have been developed including surfactant-enhanced bioremediation (SEBR), surfactant-enhanced phytoremediation (SEPR) and SER-advanced oxidation processes (SER-AOPs). In this review, the general considerations and corresponding applications of the integrated cleanup technologies are summarized and discussed. Compared with SER-AOPs, SEBR and SEPR need less operation cost, yet require more treatment time. To successfully achieve the field application of surfactant-based technologies, massive production of the cost-effective green surfactants (i.e. biosurfactants) and comprehensive evaluation of the drivers and the global cost of SER-based cleanup technologies need to be performed in the future. Copyright © 2017. Published by Elsevier Ltd.

  6. Breaking up is hard to do: why disinvestment in medical technology is harder than investment.

    PubMed

    Haas, Marion; Hall, Jane; Viney, Rosalie; Gallego, Gisselle

    2012-05-01

    Healthcare technology is a two-edged sword - it offers new and better treatment to a wider range of people and, at the same time, is a major driver of increasing costs in health systems. Many countries have developed sophisticated systems of health technology assessment (HTA) to inform decisions about new investments in new healthcare interventions. In this paper, we question whether HTA is also the appropriate framework for guiding or informing disinvestment decisions. In exploring the issues related to disinvestment, we first discuss the various HTA frameworks which have been suggested as a means of encouraging or facilitating disinvestment. We then describe available means of identifying candidates for disinvestment (comparative effectiveness research, clinical practice variations, clinical practice guidelines) and for implementing the disinvestment process (program budgeting and marginal analysis (PBMA) and related techniques). In considering the possible reasons for the lack of progress in active disinvestment, we suggest that HTA is not the right framework as disinvestment involves a different decision making context. The key to disinvestment is not just what to stop doing but how to make it happen - that is, decision makers need to be aware of funding disincentives.

  7. Effective implementation of health information technologies in U.S. hospitals.

    PubMed

    Khatri, Naresh; Gupta, Vishal

    2016-01-01

    Two issues pertaining to the effective implementation of health information technologies (HITs) in U.S. hospitals are examined. First, which information technology (IT) system is better--a homegrown or an outsourced one? In the second issue, the critical role of in-house IT expertise/capabilities in the effective implementation of HITs is investigated. The data on type of HIT system and IT expertise/capabilities were collected from a national sample of senior executives of U.S. hospitals. The data on quality of patient care were gathered from the Hospital Compare Web site. The quality of patient care was significantly higher in hospitals deploying a homegrown HIT system than hospitals deploying an outsourced HIT system. Furthermore, the professional competence and compelling vision of the chief information officer was found to be a major driver of another key IT capability of hospitals-professionalism of IT staff. The positive relationship of professionalism of IT staff with quality of patient care was mediated by proactive employee behavior. A homegrown HIT system achieves better quality of patient care than an outsourced one. The chief information officer's IT vision and the professional expertise and professionalism of IT staff are important IT capabilities in U.S. hospitals.

  8. Quality engineering tools focused on high power LED driver design using boost power stages in switch mode

    NASA Astrophysics Data System (ADS)

    Ileana, Ioan; Risteiu, Mircea; Marc, Gheorghe

    2016-12-01

    This paper is a part of our research dedicated to high power LED lamps designing. The boost-up selected technology wants to meet driver producers' tendency in the frame of efficiency and disturbances constrains. In our work we used modeling and simulation tools for implementing scenarios of the driver work when some controlling functions are executed (output voltage/ current versus input voltage and fixed switching frequency, input and output electric power transfer versus switching frequency, transient inductor voltage analysis, and transient out capacitor analysis). Some electrical and thermal stress conditions are also analyzed. Based on these aspects, a high reliable power LED driver has been designed.

  9. Taxi 'sugar daddies' and taxi queens: male taxi driver attitudes regarding transactional relationships in the Western Cape, South Africa.

    PubMed

    Potgieter, Cheryl; Strebel, Anna; Shefer, Tamara; Wagner, Claire

    2012-11-01

    Media reports are emerging on the phenomenon of young girls who travel with older mini-bus taxi drivers, and who are thought to have sex with the drivers in exchange for gifts and money. The extent to which such relationships might facilitate unsafe sexual practices and increased risks for both the men and the young women, often referred to as taxi queens, remains an important question in the light of the current challenges of HIV/AIDS in sub-Saharan Africa. However, very little research has been undertaken on this issue, especially regarding the perceptions and experiences of taxi drivers. Thus this paper aims to provide some preliminary findings on taxi drivers' attitudes and beliefs about taxi queens and their relationships with taxi drivers. A 22-item questionnaire was administered to 223 male taxi drivers in two regions in the Western Cape Province, South Africa. Taxi drivers in this study largely saw the relationship between taxi drivers and the young girls who ride with them as providing status for both the girls and drivers, and there seemed to be recognition of the transactional nature of the relationship between taxi drivers and taxi queens. The stigmatisation of young girls who ride with taxi drivers was evident. Drivers had knowledge and awareness of the risks of unsafe sex and supported condom use, although there appeared to be some uncertainty and confusion about the likelihood of HIV infection between drivers and girls. While taxi drivers recognised the role of alcohol in relationships with young girls, they seemed to deny that the abuse of drugs was common. The study highlights a number of key areas that need to be explored with men in the taxi industry, in order to address risk behaviours for both taxi drivers and the girls who ride with them.

  10. KSC Tech Transfer News, Volume 5, No. 1

    NASA Technical Reports Server (NTRS)

    Buckingham, Bruce (Editor)

    2012-01-01

    In October 2011, the White House released a presidential memorandum titled "Accelerating Technology Transfer and Commercialization of Federal Research in Support of High-Growth Businesses." It emphasized the importance of technology transfer as a driver of successful innovation to fuel economic growth, create jobs, and make U.S. industries more competitive in a global market. In response to this memorandum, NASA developed a 5-year plan for accelerating its own technology transfer activities. This plan outlines key objectives for enhancing NASA's ability to increase the rate, volume, and quality of technology transfers to industry, academia, and other Government agencies. By doing so, we are increasing the economic impact and public benefit of Federal technology investments. In addition, NASA established technology transfer as a key element of one of its Agency High Priority Performance Goals: "Enable bold new missions and make new technologies available to Government agencies and U.S. industry."What does this mean to you? In the broadest sense, NASA defines technology transfer as the utilization of NASA's technological assets- technologies, innovations, unique facilities and equipment, and technical expertise- by public and private sectors to benefit the Nation. So, if your job involves developing new technologies, writing new software, creating innovative ways to do business, performing research, or developing new technical capabilities, you could be contributing to Kennedy Space Center's (KSC) technology transfer activities by creating the technological assets that may one day be used by external partners. Furthermore, anytime you provide technical expertise to external partners, you're participating in technology transfer. The single most important step you can take to support the technology transfer process is to report new technologies and innovations ro the Technology Transfer Office. This is the critical first step in fueling the technology transfer pipeline. This is also a requirement for all Federal employees (see NPD 2091.1 B) and most NASA contractors. Detailed information on when, where, and how ro report new technology is provided on the following page. In addition, it's important that all detailed-oriented discussions about technology between NASA and external partners are documented or that they occur under formal agreements such as Space Act Agreements and Nondisclosure Agreements. Our office can assist you in putting these agreements into place, protecting NASA's interests, and providing the means to accurately measure the Agency's technology transfer activities. Technology transfer is everyone's responsibility. We need your help to ensure that NASA remains the leader in Federal technology transfer, and that the great work done at KSC provides the maximum economic and societal benefit to the Nation.

  11. The Relative Importance of Post-Acute Care and Readmissions for Post-Discharge Spending.

    PubMed

    Huckfeldt, Peter J; Mehrotra, Ateev; Hussey, Peter S

    2016-10-01

    To understand what patterns of health care use are associated with higher post-hospitalization spending. Medicare hospital, skilled nursing, inpatient rehabilitation, and home health agency claims, and Medicare enrollment data from 2007 and 2008. For 10 common inpatient conditions, we calculated variation across hospitals in price-standardized and case mix-adjusted Medicare spending in the 30 days following hospital discharge. We estimated the fraction of spending differences between low- and high-spending hospitals attributable to readmissions versus post-acute care, and within post-acute care between inpatient rehabilitation facility (IRF) versus skilled nursing facility (SNF) use. For each service, we distinguished between differences in probability of use and spending conditional on use. We identified index hospital claims and examined hospital and post-acute care occurring within a 30-day period following hospital discharge. For each Medicare Severity Diagnosis-Related Group (MS-DRG) at each hospital, we calculated average price-standardized Medicare payments for readmissions, SNFs, IRFs, and post-acute care overall (also including home health agencies and long-term care hospitals). There was extensive variation across hospitals in Medicare spending in the 30 days following hospital discharge. For example, the interquartile range across hospitals ranged from $1,245 for chronic obstructive pulmonary disease to over $4,000 for myocardial infarction MS-DRGs. The proportion of differences attributable to readmissions versus post-acute care differed across conditions. For myocardial infarction, 74 to 93 percent of the variation was due to readmissions. For hip and femur procedures and joint replacement, 72 to 92 percent of the variation was due to differences in post-acute care spending. There was also variation in the relative importance of the type of post-acute spending. For hip and femur procedures, joint replacement, and stroke, whether patients received IRF was the key driver of variation in post-acute care spending In contrast, for pneumonia and heart failure, whether patients received SNF care was the key driver of variation in post-acute spending. Through initiatives such as bundled payment, hospitals are financially responsible for spending in the post-hospitalization period. The key driver of variation in post-hospitalization spending varied greatly across conditions. For some conditions, the key driver was having a readmission, for others it was whether patients receive any post-acute care, and for others the key driver was the type of post-acute care. These findings may help hospitals implement strategies to reduce post-discharge spending. © Health Research and Educational Trust.

  12. Novice drivers' individual trajectories of driver behavior over the first three years of driving.

    PubMed

    Roman, Gabriela D; Poulter, Damian; Barker, Edward; McKenna, Frank P; Rowe, Richard

    2015-09-01

    Identifying the changes in driving behavior that underlie the decrease in crash risk over the first few months of driving is key to efforts to reduce injury and fatality risk in novice drivers. This study represented a secondary data analysis of 1148 drivers who participated in the UK Cohort II study. The Driver Behavior Questionnaire was completed at 6 months and 1, 2 and 3 years after licensure. Linear latent growth models indicated significant increases across development in all four dimensions of aberrant driving behavior under scrutiny: aggressive violations, ordinary violations, errors and slips. Unconditional and conditional latent growth class analyses showed that the observed heterogeneity in individual trajectories was explained by the presence of multiple homogeneous groups of drivers, each exhibiting specific trajectories of aberrant driver behavior. Initial levels of aberrant driver behavior were important in identifying sub-groups of drivers. All classes showed positive slopes; there was no evidence of a group of drivers whose aberrant behavior decreased over time that might explain the decrease in crash involvement observed over this period. Male gender and younger age predicted membership of trajectories with higher levels of aberrant behavior. These findings highlight the importance of early intervention for improving road safety. We discuss the implications of our findings for understanding the behavioral underpinnings of the decrease in crash involvement observed in the early months of driving. Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.

  13. Individualized assessment of driving fitness for older individuals with health, disability, and age-related concerns.

    PubMed

    Wheatley, Carol J; Di Stefano, Marilyn

    2008-08-01

    Driver licensing agencies are faced with an increasing population of drivers who are seeking to maintain driving privileges whilst coping with functional changes associated with health, disability, or aging-related issues. Some of these changes impact upon the motor, sensory, and cognitive capacities essential for safe motor vehicle operation. The driver assessment process, as provided by occupational therapists and other professionals trained in the techniques of driver rehabilitation, can provide objective data to identify driver strengths and limitations and options available to increase mobility independence via consideration of adaptive mobility equipment, vehicle choice, driver training, or alternative transportation if necessary. This article provides an overview of the driver rehabilitation specialist's assessment and training process, with an analysis of the key issues related to this form of assessment and the need for further research. The basic driver rehabilitation process is outlined including examples of common deficits, assessment considerations, and intervention approaches. The clinical and on-road assessment procedures are described, with illustrations of the reasoning process that leads to a determination of the person's overall driving competence and rehabilitation recommendations. A review of the literature is provided that examines the currently available documentation that supports this assessment and rehabilitation process. The article concludes with a review of current literature that examines the claim that detailed clinical and on-road assessment, as provided by driver rehabilitation specialists, is currently the best method for assisting drivers with complex health, disability, or aging-related issues to resume or retain driving privileges.

  14. Battery Electric Vehicles: Range Optimization and Diversification for the U.S. Drivers

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lin, Zhenhong

    2012-01-01

    Properly selecting the driving range is critical for accurately predicting the market acceptance and the resulting social benefits of BEVs. Analysis of transportation technology transition could be biased against battery electric vehicles (BEV) and mislead policy making, if BEVs are not represented with optimal ranges. This study proposes a coherent method to optimize the BEV driving range by minimizing the range-related cost, which is formulated as a function of range, battery cost, energy prices, charging frequency, access to backup vehicles, and the cost and refueling hassle of operating the backup vehicle. This method is implemented with a sample of 36,664more » drivers, representing U.S. new car drivers, based on the 2009 National Household Travel Survey data. Key findings are: 1) Assuming the near term (2015) battery cost at $405/kWh, about 98% of the sampled drivers are predicted to prefer a range below 200 miles, and about 70% below 100 miles. The most popular 20-mile band of range is 57 to77 miles, unsurprisingly encompassing the Leaf s EPA-certified 73-mile range. With range limited to 4 or 7 discrete options, the majority are predicted to choose a range below 100 miles. 2) Found as a statistically robust rule of thumb, the BEV optimal range is approximately 0.6% of one s annual driving distance. 3) Reducing battery costs could motivate demand for larger range, but improving public charging may cause the opposite. 4) Using a single range to represent BEVs in analysis could significantly underestimate their competitiveness e.g. by $3226/vehicle if BEVs are represented with 73-mile range only or by $7404/BEV if with 150-mile range only. Range optimization and diversification into 4 or 7 range options reduce such analytical bias by 78% or 90%, respectively.« less

  15. High bandwidth electro-optic technology for intersatellite optical communications

    NASA Technical Reports Server (NTRS)

    Krainak, Michael A.

    1992-01-01

    The research and development of electronic and electro-optic components for geosynchronous and low earth orbiting satellite optical high bandwidth communications at the NASA-Goddard Space Flight Center is reviewed. Intersatellite optical communications retains a strong reliance on microwave circuit technology in several areas - the microwave to optical interface, the laser transmitter modulation driver and the optical receiver. A microwave to optical interface is described requiring high bandwidth electronic downconverters and demodulators. Electrical bandwidth and current drive requirements for the laser modulation driver for three laser alternatives are discussed. Bandwidth and noise requirements are presented for optical receiver architectures.

  16. Recent developments in high average power driver technology

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Prestwich, K.R.; Buttram, M.T.; Rohwein, G.J>

    1979-01-01

    Inertial confinement fusion (ICF) reactors will require driver systems operating with tens to hundreds of megawatts of average power. The pulse power technology that will be required to build such drivers is in a primitive state of development. Recent developments in repetitive pulse power are discussed. A high-voltage transformer has been developed and operated at 3 MV in a single pulse experiment and is being tested at 1.5 MV, 5 kj and 10 pps. A low-loss, 1 MV, 10 kj, 10 pps Marx generator is being tested. Test results from gas-dynamic spark gaps that operate both in the 100 kVmore » and 700 kV range are reported. A 250 kV, 1.5 kA/cm/sup 2/, 30 ns electron beam diode has operated stably for 1.6 x 10/sup 5/ pulses.« less

  17. Ground Vehicle Convoying

    NASA Astrophysics Data System (ADS)

    Gage, Douglas W.; Pletta, J. Bryan

    1987-01-01

    Initial investigations into two different approaches for applying autonomous ground vehicle technology to the vehicle convoying application are described. A minimal capability system that would maintain desired speed and vehicle spacing while a human driver provided steering control could improve convoy performance and provide positive control at night and in inclement weather, but would not reduce driver manpower requirements. Such a system could be implemented in a modular and relatively low cost manner. A more capable system would eliminate the human driver in following vehicles and reduce manpower requirements for the transportation of supplies. This technology could also be used to aid in the deployment of teleoperated vehicles in a battlefield environment. The needs, requirements, and several proposed solutions for such an Attachable Robotic Convoy Capability (ARCC) system will be discussed. Included are discussions of sensors, communications, computers, control systems and safety issues. This advanced robotic convoy system will provide a much greater capability, but will be more difficult and expensive to implement.

  18. Cognitive characteristics of older Japanese drivers.

    PubMed

    Susilowati, Indri H; Yasukouchi, Akira

    2012-02-29

    Some causes of accidents among older drivers are: not paying attention to traffic signals; missing stop lines; and having to deal with and misjudging emergency situations. These causes of accidents reveal problems with attention and cognition. Such incidents are also related to driver perception and stress-coping mechanisms. It is important to examine the relation of stress reactions to attention and cognition as a factor influencing the causes of accidents commonly involving older drivers. Subjects were 10 young drivers (23.3 ± 3.33 years) and 25 older drivers divided into two groups (older1 [60 to 65 years] and older2 [> 65 years]). This study revealed the correlation within driver stress inventory and driver coping questionnaires parameters was observed only in older drivers. They also needed a longer response time for Trail Making Test A and B. The factors affected the attention and cognition of older drivers by age but not driving experience itself, and coping parameters such as emotion focus, reappraisal, and avoidance were not included as stress inventory parameters. Being prone to fatigue was less for younger drivers than older drivers. Because they have shorter distances, shorter drive times, and no need for expressways, older drivers also had a significantly lower risk of thrill-seeking behaviour and more patience. The intervention addressing their attention skills, aggressive feelings, and emotion focus should be considered. The technological improvements in cars will make older drivers feel safer and make driving easier which might lower the attention paid to the road, and regular driving training might be needed to assess and enhance their safety.

  19. Cognitive characteristics of older Japanese drivers

    PubMed Central

    2012-01-01

    Background Some causes of accidents among older drivers are: not paying attention to traffic signals; missing stop lines; and having to deal with and misjudging emergency situations. These causes of accidents reveal problems with attention and cognition. Such incidents are also related to driver perception and stress-coping mechanisms. It is important to examine the relation of stress reactions to attention and cognition as a factor influencing the causes of accidents commonly involving older drivers. Finding Subjects were 10 young drivers (23.3 ± 3.33 years) and 25 older drivers divided into two groups (older1 [60 to 65 years] and older2 [> 65 years]). This study revealed the correlation within driver stress inventory and driver coping questionnaires parameters was observed only in older drivers. They also needed a longer response time for Trail Making Test A and B. The factors affected the attention and cognition of older drivers by age but not driving experience itself, and coping parameters such as emotion focus, reappraisal, and avoidance were not included as stress inventory parameters. Being prone to fatigue was less for younger drivers than older drivers. Because they have shorter distances, shorter drive times, and no need for expressways, older drivers also had a significantly lower risk of thrill-seeking behaviour and more patience. Conclusion The intervention addressing their attention skills, aggressive feelings, and emotion focus should be considered. The technological improvements in cars will make older drivers feel safer and make driving easier which might lower the attention paid to the road, and regular driving training might be needed to assess and enhance their safety. PMID:22738158

  20. Beam wavefront and farfield control for ICF laser driver

    NASA Astrophysics Data System (ADS)

    Dai, Wanjun; Deng, Wu; Zhang, Xin; Jiang, Xuejun; Zhang, Kun; Zhou, Wei; Zhao, Junpu; Hu, Dongxia

    2010-10-01

    Five main problems of beam wavefront and farfield control in ICF laser driver are synthetically discussed, including control requirements, beam propagation principle, distortions source control, system design and adjustment optimization, active wavefront correction technology. We demonstrate that beam can be propagated well and the divergence angle of the TIL pulses can be improved to less than 60μrad with solving these problems, which meets the requirements of TIL. The results can provide theoretical and experimental support for wavefront and farfield control designing requirements of the next large scale ICF driver.

  1. Distracted driving: a neglected epidemic.

    PubMed

    Dildy, Dale W

    2012-10-01

    In 2009, the National Highway Traffic Safety Administration (NHTSA) estimated nearly 6,000 distracted driver fatalities and 515,000 injuries in the United States alone. Distracted driving is a worldwide problem that needs to be addressed. Software is available to disable cell phone usage while driving, but using the advanced technology may require legislation along with a renewed sense of driver responsibility.

  2. Vehicle Controller

    NASA Technical Reports Server (NTRS)

    1985-01-01

    UNISTICK is an airplane-like joystick being developed by Johnson Engineering under NASA and VA sponsorship. It allows a driver to control a vehicle with one hand, and is based upon technology developed for the Apollo Lunar Landings of the 1970's. It allows severely handicapped drivers to operate an automobile or van easily. The system is expected to be in production by March 1986.

  3. DIRECT operational field test evaluation natural use study. Part 3, Evaluation of driver behavior and measurement of effectiveness of DIRECT communications technologies based on vehicle tracking around incidents

    DOT National Transportation Integrated Search

    1998-08-01

    Vehicle tracking systems were installed on all DIRECT vehicles to help investigate the : relationships between the drivers actual travel experiences and their opinions about the : systems they used. The purpose of this report is to look more caref...

  4. Examining the Relationships between KPI Technology Factor and ICT/Enterprise Alignment

    ERIC Educational Resources Information Center

    Taylor, Carolyn

    2013-01-01

    "Fortune" Global 500 Corporations understand that achieving alignment between information and communication technology and enterprise is a major issue. There is much evidence that supports the notion that strategic alignment of information and communication technology (ICT) and enterprise are drivers of economic growth. Addressing…

  5. French Health Technology Assessment of Antineoplastic Drugs Indicated in the Treatment of Solid Tumours: Perspective for Future Trends.

    PubMed

    Chouaid, Christos; Borget, Isabelle; Braun, Eric; Bazil, Marie-Laure; Schaetz, Dominique; Rémuzat, Cécile; Toumi, Mondher

    2016-08-01

    France is one of the European countries that spend the most on oncology drugs. To keep pharmaceutical expenditure under control, Health Authorities highly scrutinize market access of costly medicines. To assess current and future trends in French health technology assessment (HTA) of antineoplastic drugs indicated in the treatment of solid tumours. A review of the SMR and ASMR drivers of the Transparency Committee (CT) opinions issued for antineoplastic drugs indicated in the treatment of solid tumours and approved between 2009 and 2014 was performed to assess current trends in French health technology assessment (HTA), complemented by an expert board consultation to capture the critical issues on the future of antineoplastic drugs HTA. Thirty-one drugs indicated for the treatment of solid tumours were identified (77 % targeted therapies). Initial CT assessments were available for 26 drugs. Four key items in the CT assessment were identified: 1) Clinical trial methodology; 2) Acceptance of progression-free survival (PFS) as a valuable endpoint; 3) Transferability of clinical trials in clinical practice; 4) Unpredictability of CT decisions. Experts raised the important development of personalised medicines in oncology and key challenges for oncology products to generate information expected from HTA perspective. The French system remains committed to its values and philosophy (access of all innovations for everybody) which are threatened by the increasing launch of innovative therapies and budget constraint. Both HTA decision framework evolution and revision of the current pricing process should be considered in France to cope with these new challenges.

  6. Modular Orbital Demonstration of an Evolvable Space Telescope

    NASA Astrophysics Data System (ADS)

    Baldauf, Brian

    2016-06-01

    The key driver for a telescope's sensitivityis directly related to the size of t he mirror area that collects light from the objects being observed.The "Search for Life" via imaging of exoplanets is a mission that requires extremely stable telescopes with apertures in the 10 m to 20 m range. The HDST envisioned for this mission would have an aperture >10 m, which is a larger payload than can be delivered to space using a single launch vehicle. Building and assembling the mirror segments enabling large telescopes will likely require multiple launches and assembly in space. The Optical Telescope Assembly for HDST is a primary mission cost driver. Enabling affordable solutions for this next generation of large aperture space-based telescope are needed.This reports on the concept for the MODEST, which demonstrates on-orbit robotic and/or astronaut assembly of a precision optical telescope in space. It will facilitate demonstration of active correction of phase and mirror shape. MODEST is proposed to be delivered to the ISS using standard Express Logistics Carriers and can mounted to one of a variety of ISS pallets. Post-assembly value includes space, ground, and environmental studies, a testbed for new instruments, and a tool for student's exploration of space. This demonstration program for next generation mirror technology provides significant risk reduction and demonstrates the technology in a six-mirror phased telescope. Key features of the demonstration include the use of an active primary optical surface with wavefront feedback control that allows on-orbit optimization and demonstration of precise surface control to meet optical system wavefront and stability requirements.MODEST will also be used to evaluate advances in lightweight mirror and metering structure materials such as SiC or Ceramic Matrix Composite that have excellent mechanical and thermal properties, e.g. high stiffness, high thermal conductivity, and low thermal expansion. It has been demonstrated that mirrors built from these materials can be rapidly replicated in a highly cost effective manner, making these materials excellent candidates for a low cost, high performance OTA.

  7. Systematic review on the evaluation criteria of orphan medicines in Central and Eastern European countries.

    PubMed

    Zelei, Tamás; Molnár, Mária J; Szegedi, Márta; Kaló, Zoltán

    2016-06-04

    In case of orphan drugs applicability of the standard health technology assessment (HTA) process is limited due to scarcity of good clinical and health economic evidence. Financing these premium priced drugs is more controversial in the Central and Eastern European (CEE) region where the public funding resources are more restricted, and health economic justification should be an even more important aspect of policy decisions than in higher income European countries. To explore and summarize the recent scientific evidence on value drivers related to the health technology assessment of ODs with a special focus on the perspective of third party payers in CEE countries. The review aims to list all potentially relevant value drivers in the reimbursement process of orphan drugs. A systematic literature review was performed; PubMed and Scopus databases were systematically searched for relevant publications until April 2015. Extracted data were summarized along key HTA elements. From the 2664 identified publications, 87 contained relevant information on the evaluation criteria of orphan drugs, but only 5 had direct information from the CEE region. The presentation of good clinical evidence seems to play a key role especially since this should be the basis of cost-effectiveness analyses, which have more importance in resource-constrained economies. Due to external price referencing of pharmaceuticals, the relative budget impact of orphan drugs is expected to be higher in CEE than in Western European (WE) countries unless accessibility of patients remains more limited in poorer European regions. Equity principles based on disease prevalence and non-availability of alternative treatment options may increase the price premium, however, societies must have some control on prices and a rationale based on multiple criteria in reimbursement decisions. The evaluation of orphan medicines should include multiple criteria to appropriately measure the clinical added value of orphan drugs. The search found only a small number of studies coming from CEE, therefore European policies on orphan drugs may be based largely on experiences in WE countries. More research should be done in the future in CEE because financing high-priced orphan drugs involves a greater burden for these countries.

  8. A Review of Accident Modelling Approaches for Complex Critical Sociotechnical Systems

    DTIC Science & Technology

    2008-01-01

    several Signals Passed at Danger ( SPADs ) but a signal sighting committee was not convened 4. An inspection of the signalling system at Watford...Junction was never carried out 5. The driver did not know of the reduced overlap between signals 6. The driver had committed SPADs recently and...cause. One philosophical approach to causation views counterfactual dependence as the key to the explanation of causal facts: for example, events c (the

  9. From cheetahs to chimpanzees: a comparative review of the drivers of human-carnivore conflict and human-primate conflict.

    PubMed

    Dickman, Amy J

    2012-01-01

    Human-wildlife conflict is a growing conservation threat, and is increasingly of importance to primate conservationists. Despite this, relatively little work has been done to date on the drivers of human-primate conflict, especially compared to other conflict-causing taxa such as large carnivores. However, the drivers of conflict are often very similar across species, so conflict researchers can learn important lessons from work conducted on other taxa. This paper discusses 8 key factors which are likely to affect how hostile people are towards wildlife and any damage they cause--6 of these are common to both carnivores and primates, while one is much more applicable to carnivores and the other is specific to primates. These conflict drivers involve numerous social and cultural factors, and highlight the importance of truly understanding the local drivers of conflict in order to develop effective mitigation strategies. Copyright © 2013 S. Karger AG, Basel.

  10. Drivers for OSH interventions in small and medium-sized enterprises.

    PubMed

    Cagno, Enrico; Masi, Donato; Leão, Celina Pinto

    2016-01-01

    The debate concerning occupational safety and health (OSH) interventions has recently focused on the need of improving the evaluation of interventions, and in particular on the need for providing information about why the intervention worked or not, under what circumstances and in which context. Key concepts in the analysis of the context are the drivers, i.e., those factors enabling, fostering or facilitating OSH interventions. However, the concept of driver for an OSH intervention is both confused and contested. Although the term is widely used, there is little consensus on how drivers should be understood, how important they are in different contexts and how they can facilitate interventions. This exploratory study based on interviews with the owner-managers and the safety officers of small and medium-sized enterprises (SMEs) gives an overview of the most characteristic drivers for OSH interventions. The results will be used to make an initial evaluation of SMEs' needs, and will help orient interventions and future research.

  11. Environmental Quality and the U.S. Power Sector: Air Quality, Land Use and Environmental Justice

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Massetti, Emanuele; Brown, Marilyn Ann; Lapsa, Melissa Voss

    This baseline report summarizes key environmental quality issues associated with electricity generation, transmission, distribution, and end use in the United States. Its scope includes non-greenhouse gas air pollution (i.e., sulfur dioxide, nitrogen oxides, particulate matter and hazardous air pollutants), land use, water pollution, ecological impacts, human health, and environmental justice. The discussion characterizes both current impacts and recent trends, as well as assessments of key drivers of change. For example, the air emissions section includes a quantitative decomposition analysis of the drivers of change in sulfur dioxide emissions reductions from coal-fired power plants. The report is divided into four topicalmore » sections: air emissions, land use and ecology, water quality, and environmental justice.« less

  12. Origins Space Telescope: Study Plan

    NASA Astrophysics Data System (ADS)

    Nayyeri, Hooshang; Cooray, Asantha; Origins Space Telescope Study Team

    2018-01-01

    The Origins Space Telescope (OST) is the mission concept for the Far-Infrared Surveyor, a study in development by NASA in preparation for the 2020 Astronomy and Astrophysics Decadal Survey. Origins is planned to be a large aperture, actively-cooled telescope covering a wide span of the mid- to far-infrared spectrum. Its spectrographs will enable 3D surveys of the sky that will discover and characterize the most distant galaxies, Milky-Way, exoplanets, and the outer reaches of our Solar system. Origins will enable flagship-quality general observing programs led by the astronomical community in the 2030s. The Science and Technology Definition Team (STDT) would like to hear your science needs and ideas for this mission. The team can be contacted at firsurveyor_info@lists.ipac.caltech.edu. This presentation will provide a summary of the OST STDT, the OST Study Team based at NASA Goddard Space Flight Center, study partners, and the advisory panel to the study. This presentation will also summarize recent activities, including the process used to reach a decision on the mission architecture, the identification of key science drivers, and the key study milestones between 2017 and 2020.

  13. HVM die yield improvement as a function of DRSEM ADC

    NASA Astrophysics Data System (ADS)

    Maheshwary, Sonu; Haas, Terry; McGarvey, Steve

    2010-03-01

    Given the current manufacturing technology roadmap and the competitiveness of the global semiconductor manufacturing environment in conjunction with the semiconductor manufacturing market dynamics, the market place continues to demand a reduced die manufacturing cost. This continuous pressure on lowering die cost in turn drives an aggressive yield learning curve, a key component of which is defect reduction of manufacturing induced anomalies. In order to meet and even exceed line and die yield targets there is a need to revamp defect classification strategies and place a greater emphasize on increasing the accuracy and purity of the Defect Review Scanning Electron Microscope (DRSEM) Automated Defect Classification (ADC) results while placing less emphasis on the ADC results of patterned/un-patterned wafer inspection systems. The increased emphasis on DRSEM ADC results allows for a high degree of automation and consistency in the classification data and eliminates variance induced by the manufacturing staff. This paper examines the use of SEM based Auto Defect Classification in a high volume manufacturing environment as a key driver in the reduction of defect limited yields.

  14. Origins Space Telescope: Study Plan

    NASA Astrophysics Data System (ADS)

    Cooray, Asantha R.; Origins Space Telescope Study Team

    2017-01-01

    The Origins Space Telescope (OST) is the mission concept for the Far-Infrared Surveyor, a study in development by NASA in preparation for the 2020 Astronomy and Astrophysics Decadal Survey. Origins is planned to be a large aperture, actively-cooled telescope covering a wide span of the mid- to far-infrared spectrum. Its spectrographs will enable 3D surveys of the sky that will discover and characterize the most distant galaxies, Milky-Way, exoplanets, and the outer reaches of our Solar system. Origins will enable flagship-quality general observing programs led by the astronomical community in the 2030s. The Science and Technology Definition Team (STDT) would like to hear your science needs and ideas for this mission. The team can be contacted at firsurveyor_info@lists.ipac.caltech.edu. This presentation will provide a summary of the OST STDT, the OST Study Team based at NASA Goddard Space Flight Center, study partners, and the advisory panel to the study. This presentation will also summarize recent activities, including the process used to reach a decision on the mission architecture, the identification of key science drivers, and the key study milestones between 2017 and 2020.

  15. An extended continuum model accounting for the driver's timid and aggressive attributions

    NASA Astrophysics Data System (ADS)

    Cheng, Rongjun; Ge, Hongxia; Wang, Jufeng

    2017-04-01

    Considering the driver's timid and aggressive behaviors simultaneously, a new continuum model is put forwarded in this paper. By applying the linear stability theory, we presented the analysis of new model's linear stability. Through nonlinear analysis, the KdV-Burgers equation is derived to describe density wave near the neutral stability line. Numerical results verify that aggressive driving is better than timid act because the aggressive driver will adjust his speed timely according to the leading car's speed. The key improvement of this new model is that the timid driving deteriorates traffic stability while the aggressive driving will enhance traffic stability. The relationship of energy consumption between the aggressive and timid driving is also studied. Numerical results show that aggressive driver behavior can not only suppress the traffic congestion but also reduce the energy consumption.

  16. Automotive Radar and Lidar Systems for Next Generation Driver Assistance Functions

    NASA Astrophysics Data System (ADS)

    Rasshofer, R. H.; Gresser, K.

    2005-05-01

    Automotive radar and lidar sensors represent key components for next generation driver assistance functions (Jones, 2001). Today, their use is limited to comfort applications in premium segment vehicles although an evolution process towards more safety-oriented functions is taking place. Radar sensors available on the market today suffer from low angular resolution and poor target detection in medium ranges (30 to 60m) over azimuth angles larger than ±30°. In contrast, Lidar sensors show large sensitivity towards environmental influences (e.g. snow, fog, dirt). Both sensor technologies today have a rather high cost level, forbidding their wide-spread usage on mass markets. A common approach to overcome individual sensor drawbacks is the employment of data fusion techniques (Bar-Shalom, 2001). Raw data fusion requires a common, standardized data interface to easily integrate a variety of asynchronous sensor data into a fusion network. Moreover, next generation sensors should be able to dynamically adopt to new situations and should have the ability to work in cooperative sensor environments. As vehicular function development today is being shifted more and more towards virtual prototyping, mathematical sensor models should be available. These models should take into account the sensor's functional principle as well as all typical measurement errors generated by the sensor.

  17. Understanding road safety in Kenya: views of matatu drivers.

    PubMed

    Raynor, Nicolas J; Mirzoev, Tolib

    2014-09-01

    Road traffic accidents (RTAs) are estimated to cause 1.3 million deaths and 20-50 million injuries worldwide. Road safety is a challenge in Kenya with causes being multi-factorial. Matatus (minibuses) are involved in a large proportion of accidents. A literature review was completed to identify key issues and refine the scope of the study. The fieldwork included 20 semi-structured interviews with matatu drivers. All participants were male, with driving experience of 1-20 years. Thematic framework was used for analysis. Some unstructured observations on different road users and their behaviours were also recorded. Literature showed that the causes of RTAs in Kenya are multi-factorial, but that human factors play a large part. There is also an evidence gap concerning matatu drivers, who are key stakeholders in road safety. Fieldwork showed that the matatu industry creates financial pressures on drivers and an excessive level of competition, leading to dangerous driving. Corruption of traffic police appears to be a major barrier to improving road safety, as road safety legislation is not enforced, and bribery has become the cultural norm. The general public, including passengers and private vehicles owners, also cause problems by failing to understand their role in road safety and placing the blame on others. The key policy implication for improving road safety in Kenya is seeking measures to ensure responsibility by all road users through awareness raising in the short-term and reforming the matatu industry and addressing the root causes of corruption in the longer term. © The Author 2014. Published by Oxford University Press on behalf of Royal Society of Tropical Medicine and Hygiene. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  18. Advancing Methods for Estimating Soil Nitrous Oxide Emissions by Incorporating Freeze-Thaw Cycles into a Tier 3 Model-Based Assessment

    NASA Astrophysics Data System (ADS)

    Ogle, S. M.; DelGrosso, S.; Parton, W. J.

    2017-12-01

    Soil nitrous oxide emissions from agricultural management are a key source of greenhouse gas emissions in many countries due to the widespread use of nitrogen fertilizers, manure amendments from livestock production, planting legumes and other practices that affect N dynamics in soils. In the United States, soil nitrous oxide emissions have ranged from 250 to 280 Tg CO2 equivalent from 1990 to 2015, with uncertainties around 20-30 percent. A Tier 3 method has been used to estimate the emissions with the DayCent ecosystem model. While the Tier 3 approach is considerably more accurate than IPCC Tier 1 methods, there is still the possibility of biases in emission estimates if there are processes and drivers that are not represented in the modeling framework. Furthermore, a key principle of IPCC guidance is that inventory compilers estimate emissions as accurately as possible. Freeze-thaw cycles and associated hot moments of nitrous oxide emissions are one of key drivers influencing emissions in colder climates, such as the cold temperate climates of the upper Midwest and New England regions of the United States. Freeze-thaw activity interacts with management practices that are increasing N availability in the plant-soil system, leading to greater nitrous oxide emissions during transition periods from winter to spring. Given the importance of this driver, the DayCent model has been revised to incorproate freeze-thaw cycles, and the results suggests that including this driver can significantly modify the emissions estimates in cold temperate climate regions. Consequently, future methodological development to improve estimation of nitrous oxide emissions from soils would benefit from incorporating freeze-thaw cycles into the modeling framework for national territories with a cold climate.

  19. Special Considerations in Distracted Driving with Teens

    PubMed Central

    Durbin, Dennis R; McGehee, Daniel V; Fisher, Donald; McCartt, Anne

    2014-01-01

    Novice teen drivers have long been known to have an increased risk of crashing, as well as increased tendencies toward unsafe and risky driving behaviors. Teens are unique as drivers for several reasons, many of which have implications specifically in the area of distracted driving. This paper reviews several of these features, including the widespread prevalence of mobile device use by teens, their lack of driving experience, the influence of peer passengers as a source of distraction, the role of parents in influencing teens’ attitudes and behaviors relevant to distracted driving and the impact of laws designed to prevent mobile device use by teen drivers. Recommendations for future research include understanding how engagement in a variety of secondary tasks by teen drivers affects their driving performance or crash risk; understanding the respective roles of parents, peers and technology in influencing teen driver behavior; and evaluating the impact of public policy on mitigating teen crash risk related to driver distraction. PMID:24776228

  20. Extending parental mentoring using an event-triggered video intervention in rural teen drivers.

    PubMed

    McGehee, Daniel V; Raby, Mireille; Carney, Cher; Lee, John D; Reyes, Michelle L

    2007-01-01

    Teen drivers are at high risk for car crashes, especially during their first years of licensure. Providing novice teen drivers and their parents with a means of identifying their risky driving maneuvers may help them learn from their mistakes, thereby reducing their crash propensity. During the initial phase of learning, adult or parental supervision often provides such guidance. However, once teens obtain their license, adult supervision is no longer mandated, and teens are left to themselves to continue the learning process. This study is the first of its type to enhance this continued learning process using an event-triggered video device. By pairing this new technology with parental feedback in the form of a weekly video review and graphical report card, we extend parents' ability to teach their teens even after they begin driving independently. Twenty-six 16- to 17-year-old drivers were recruited from a small U.S. Midwestern rural high school. We equipped their vehicles with an event-triggered video device, designed to capture 20-sec clips of the forward and cabin views whenever the vehicle exceeded lateral or forward threshold accelerations. Preliminary findings suggest that combining this emerging technology with parental weekly review of safety-relevant incidents resulted in a significant decrease in events for the more at-risk teen drivers. Implications for how such an intervention could be implemented within GDL are also discussed.

  1. The Advanced Technology Large Aperture Space Telescope (ATLAST): Science Drivers, Technology Developments, and Synergies with Other Future Facilities

    NASA Technical Reports Server (NTRS)

    Postman, Marc; Brown, Tom; Sembach, Kenneth; Giavalisco, Mauro; Traub, Wesley; Stapelfeldt, Karl; Calzetti, Daniela; Oegerle, William; Rich, R. Michael; Stahl, H. Philip; hide

    2011-01-01

    The Advanced Technology Large-Aperture Space Telescope (ATLAST) is a concept for an 8-meter to 16-meter UVOIR space observatory for launch in the 2025-2030 era. ATLAST will allow astronomers to answer fundamental questions at the forefront of modern astrophysics, including "Is there life elsewhere in the Galaxy?" We present a range of science drivers that define the main performance requirements for ATLAST (8 to 16 milliarcsec angular resolution, diffraction limited imaging at 0.5 m wavelength, minimum collecting area of 45 square meters, high sensitivity to light wavelengths from 0.1 m to 2.4 m, high stability in wavefront sensing and control). We will also discuss the synergy between ATLAST and other anticipated future facilities (e.g., TMT, EELT, ALMA) and the priorities for technology development that will enable the construction for a cost that is comparable to current generation observatory-class space missions.

  2. New Prostate Cancer Treatment Target

    Cancer.gov

    Researchers have identified a potential alternative approach to blocking a key molecular driver of an advanced form of prostate cancer, called androgen-independent or castration-resistant prostate cancer.

  3. Transportation and aging: a research agenda for advancing safe mobility.

    PubMed

    Dickerson, Anne E; Molnar, Lisa J; Eby, David W; Adler, Geri; Bédard, Michel; Berg-Weger, Marla; Classen, Sherrilene; Foley, Daniel; Horowitz, Amy; Kerschner, Helen; Page, Oliver; Silverstein, Nina M; Staplin, Loren; Trujillo, Leonard

    2007-10-01

    We review what we currently know about older driver safety and mobility, and we highlight important research needs in a number of key areas that hold promise for achieving the safety and mobility goals for the aging baby boomers and future generations of older drivers. Through the use of a framework for transportation and safe mobility, we describe key areas of screening and assessment, remediation and rehabilitation, vehicle design and modification, technological advancements, roadway design, transitioning to nondriving, and alternative transportation to meet the goals of crash prevention and mobility maintenance for older adults. Four cross-cutting themes emerged from this review: safe transportation for older adults is important; older adults have a variety of needs, abilities, and resources; research to help meet the transportation needs of older adults may be of benefit to persons with disabilities; and transportation issues concerning older adults are multifaceted. Safe mobility is essential to continued engagement in civic, social, and community life, and to the human interactions necessary for health, well-being, and quality of life. When safe driving is no longer possible for older adults, safe and practicable alternative transportation must be available. Furthermore, older adults are individuals; they have specific needs, abilities, and resources. Not all older adults will have difficulty meeting their transportation needs and no single transportation solution will work for all people. Research and countermeasures intended to help meet the transportation needs of older adults will likely also benefit younger users of the transportation system, particularly those with disabilities. The issues surrounding the maintenance of safe transportation for older adults will require an interdisciplinary research approach if we are to make significant progress in the next decade as the baby boomers begin to reach age 70.

  4. Smart Roadside System for Driver Assistance and Safety Warnings: Framework and Applications

    PubMed Central

    Jang, Jeong Ah; Kim, Hyun Suk; Cho, Han Byeog

    2011-01-01

    The use of newly emerging sensor technologies in traditional roadway systems can provide real-time traffic services to drivers through Telematics and Intelligent Transport Systems (ITSs). This paper introduces a smart roadside system that utilizes various sensors for driver assistance and traffic safety warnings. This paper shows two road application models for a smart roadside system and sensors: a red-light violation warning system for signalized intersections, and a speed advisory system for highways. Evaluation results for the two services are then shown using a micro-simulation method. In the given real-time applications for drivers, the framework and certain algorithms produce a very efficient solution with respect to the roadway type features and sensor type use. PMID:22164025

  5. “Good passengers and not good passengers:” Adolescent drivers’ perceptions about inattention and peer passengers

    PubMed Central

    Sommers, Marilyn S.

    2016-01-01

    Purpose The purpose of this qualitative focus group elicitation research study was to explore teen driver perceptions of peer passengers and driver inattention. Design & Methods We utilized focus groups for data collection and content analysis to analyze the data, both of which were guided by the Theory of Planned Behavior. We conducted 7 focus groups with 30 teens, ages 16–18, licensed for ≤1 year to examine attitudes, perceived behavioral control, and norms related to driving inattention and peer passengers. Results The sample was 50% male, mean age 17.39 (sd 0.52) with mean length of licensure 173.7 days (sd 109.2). Three themes emerged: 1) “Good and not good” passengers; 2) Passengers and technology as harmful and helpful; and 3) The driver is in charge. Conclusions While passengers can be a source of distraction, our participants also identified passenger behaviors that reduced risk, such as assistance with technology and guidance for directions. Practical Implications An understanding of teens’ perceptions of peer passengers can contribute to the development of effective interventions targeting teen driver inattention. Nurses are well-positioned to contribute to these teen crash prevention efforts. PMID:27496828

  6. Older driver training using video and global positioning system technology--a randomized controlled trial.

    PubMed

    Porter, Michelle M

    2013-05-01

    There is emerging evidence that older driver training programs with on-road instruction are more effective than driver education programs that are conducted only in the classroom. Although most programs have provided this additional in-vehicle training with a driving instructor and a dual-braked vehicle, technology could assist in providing this feedback. It was hypothesized that participants who received video and global positioning system (GPS) feedback (Video group) in addition to classroom education would improve to a greater extent than those who received a classroom-based course alone (Education) or Control participants. Fifty-four participants (32 men and 22 women), 70-89 years old, randomized to one of the three groups, completed the study. All participants underwent pre- and postintervention driving tests, in their own vehicle, on a standardized route, that were recorded with video and GPS equipment. The Video group met with a driving instructor to receive feedback on their driving errors in their preintervention driving test. A blinded assessor scored all driving tests in random order. The Video group significantly reduced their driving errors by 25% (p < .05) following the intervention, whereas the other two groups did not change significantly. Fifty-two percent of participants from the Video group improved their global safety rating, whereas only 5.3% in the Control and 22.2% in the Education groups did. This study suggests that direct driving feedback using video and GPS technology could be an effective and novel means to provide older driver education.

  7. Low power laser driver design in 28nm CMOS for on-chip and chip-to-chip optical interconnect

    NASA Astrophysics Data System (ADS)

    Belfiore, Guido; Szilagyi, Laszlo; Henker, Ronny; Ellinger, Frank

    2015-09-01

    This paper discusses the challenges and the trade-offs in the design of laser drivers for very-short distance optical communications. A prototype integrated circuit is designed and fabricated in 28 nm super-low-power CMOS technology. The power consumption of the transmitter is 17.2 mW excluding the VCSEL that in our test has a DC power consumption of 10 mW. The active area of the driver is only 0.0045 mm2. The driver can achieve an error-free (BER < 10 -12) electrical data-rate of 25 Gbit/s using a pseudo random bit sequence of 27 -1. When the driver is connected to the VCSEL module an open optical eye is reported at 15 Gbit/s. In the tested bias point the VCSEL module has a measured bandwidth of 10.7 GHz.

  8. Driving into the Sunset: Supporting Cognitive Functioning in Older Drivers

    PubMed Central

    Young, Mark S.; Bunce, David

    2011-01-01

    The rise in the aging driver population presents society with a significant challenge—how to maintain safety and mobility on the roads. On the one hand, older drivers pose a higher risk of an at-fault accident on a mile-for-mile basis; on the other hand, independent mobility is a significant marker of quality of life in aging. In this paper, we review the respective literatures on cognitive neuropsychology and ergonomics to suggest a previously unexplored synergy between these two fields. We argue that this conceptual overlap can form the basis for future solutions to what has been called “the older driver problem.” Such solutions could be found in a range of emerging driver assistance technologies offered by vehicle manufacturers, which have the potential to compensate for the specific cognitive decrements associated with aging that are related to driving. PMID:21748014

  9. Evolutionary consequences of multidriver environmental change in an aquatic primary producer.

    PubMed

    Brennan, Georgina L; Colegrave, Nick; Collins, Sinéad

    2017-09-12

    Climate change is altering aquatic environments in a complex way, and simultaneous shifts in many properties will drive evolutionary responses in primary producers at the base of both freshwater and marine ecosystems. So far, evolutionary studies have shown how changes in environmental drivers, either alone or in pairs, affect the evolution of growth and other traits in primary producers. Here, we evolve a primary producer in 96 unique environments with different combinations of between one and eight environmental drivers to understand how evolutionary responses to environmental change depend on the identity and number of drivers. Even in multidriver environments, only a few dominant drivers explain most of the evolutionary changes in population growth rates. Most populations converge on the same growth rate by the end of the evolution experiment. However, populations adapt more when these dominant drivers occur in the presence of other drivers. This is due to an increase in the intensity of selection in environments with more drivers, which are more likely to include dominant drivers. Concurrently, many of the trait changes that occur during the initial short-term response to both single and multidriver environmental change revert after about 450 generations of evolution. In future aquatic environments, populations will encounter differing combinations of drivers and intensities of selection, which will alter the adaptive potential of primary producers. Accurately gauging the intensity of selection on key primary producers will help in predicting population size and trait evolution at the base of aquatic food webs.

  10. Legislative advocacy is key to addressing teen driving deaths

    PubMed Central

    Gillan, J S

    2006-01-01

    The increased crash risk of young, novice drivers, especially in their teenage years, has been a growing concern at both the state and federal levels. Teenage drivers are involved in fatal crashes at more than double the rate of the rest of the population per 100 000 licensed drivers. The best way of stemming these losses is to enact laws adopting graduated licensure systems that restrict young, novice drivers to conditions that reduce crash risk exposure when they first operate motor vehicles and to educate the public on the need for this legislation. Legislated teenage driving restrictions involve night‐time vehicle driving restrictions, prohibitions on other teenage passengers, and the required presence of supervising adults. These restrictions are relaxed as teenage drivers successfully progress through initial and intermediate stages of graduated licensure before being granted unrestricted driver licenses. Unfortunately, many states have incomplete graduated licensing systems that need further legislative action to raise them to the desirable three‐stage system that has been shown repeatedly to produce the greatest safety benefits. These state efforts should be buttressed by federal legislation that has proved to be crucial in allied driver behavioral concerns. Because reducing crash risk involves other strategies, stringent enforcement of primary seat belt laws as well as improved motor vehicle crash avoidance capabilities and crashworthiness must accompany efforts to reduce young driver crash risk. PMID:16788112

  11. Measuring the distribution of equity in terms of energy, environmental, and economic costs in the fuel cycles of alternative fuel vehicles with hydrogen pathway scenarios

    NASA Astrophysics Data System (ADS)

    Meyer, Patrick E.

    Numerous analyses exist which examine the energy, environmental, and economic tradeoffs between conventional gasoline vehicles and hydrogen fuel cell vehicles powered by hydrogen produced from a variety of sources. These analyses are commonly referred to as "E3" analyses because of their inclusion of Energy, Environmental, and Economic indicators. Recent research as sought a means to incorporate social Equity into E3 analyses, thus producing an "E4" analysis. However, E4 analyses in the realm of energy policy are uncommon, and in the realm of alternative transportation fuels, E4 analyses are extremely rare. This dissertation discusses the creation of a novel E4 simulation tool usable to weigh energy, environmental, economic, and equity trade-offs between conventional gasoline vehicles and alternative fuel vehicles, with specific application to hydrogen fuel cell vehicles. The model, dubbed the F uel Life-cycle Analysis of Solar Hydrogen -- Energy, Environment, Economic & Equity model, or FLASH-E4, is a total fuel-cycle model that combines energy, environmental, and economic analysis methodologies with the addition of an equity analysis component. The model is capable of providing results regarding total fuel-cycle energy consumption, emissions production, energy and environmental cost, and level of social equity within a population in which low-income drivers use CGV technology and high-income drivers use a number of advanced hydrogen FCV technologies. Using theories of equity and social indicators conceptually embodied in the Lorenz Curve and Gini Index, the equity of the distribution of societal energy and environmental costs are measured for a population in which some drivers use CGVs and other drivers use FCVs. It is found, based on baseline input data representative of the United States (US), that the distribution of energy and environmental costs in a population in which some drivers use CGVs and other drivers use natural gas-based hydrogen FCVs can be moderately inequitable. However, the distribution of energy and environmental costs in a population in which some drivers use CGVs and other drivers use solar-electrolysis-based FCVs can be extremely inequitable. Further, it is found that the method of production and delivery of hydrogen (i.e. centralized production or refueling station-based production) can have an impact on the equity of energy and environmental costs. The implications of these results are interesting, in that wealthy people purchase FCVs that have high upfront costs and very low societal energy and environmental costs. Simultaneously, however, low-income people purchase CGVs that have low upfront costs and very high societal energy and environmental costs. In this situation, due to the high-polluting nature of CGV technology in relation to FCV technology, CGV drivers account for more than their equitable share of energy and environmental costs. Scenarios are conducted which explore modifications of assumptions, such as the price of oil, price of natural gas, cost to offset emissions, consumer purchase price of FCVs, and the level of taxation on the cost streams. Among other findings, it is found that altering the purchase price of an FCV has the greatest impact on social equity whereas altering the cost to offset fuel-cycle emissions has the least impact, indicating that policy mechanisms aimed at incentivizing FCVs may have a more positive impact on social equity than policies aimed at mitigating emissions. Based on the results of the scenario analysis, policy recommendations are formulated which seek to maximize social equity in populations in which not all drivers use the same vehicular technology. The policies, if implemented as a single portfolio, would assist a systematic deviation away from the fossil fuel energy economy while ensuring that social equity is preserved to the greatest degree possible. (Abstract shortened by UMI.)

  12. Knowledge, Risk Perception and Practice Regarding Tuberculosis Transmission among Long Distance Bus Drivers in Addis Ababa, Ethiopia: A Cross Sectional Study.

    PubMed

    Gebrehiwot, Tsegaye Tewelde; Tesfamichael, Fessahaye Alemseged

    2017-11-01

    Window opening during bus transportation is recommended as a tuberculosis prevention strategy.Yet, drivers are affected by lack knowledge and risk perception of passengers and assistants. Boosting knowledge of and notifying the high risk of tuberculosis transmission for every passenger could be too costly. However, strategies targeting bus drivers as key agents unlike targeting all passengers might be less costly for window opening. Data were collected from November 18/2014 to December 21/2014 in inter-region bus stations of Addis Ababa using cross sectional study design. Samples of 306 participants were selected using simple random sampling, and data were collected through face-to-face interview. Data were entered into Epi-data version 3.1 andanalyzed using IBM SPSS version 21. From a sample of 306 bus drivers, 303 were interviewed. Nine in ten and nearly half of participants believed in the need for opening all windows and avoiding overcrowding of passengers as TB preventive measures respectively. Few bus drivers (7.3%) believed that bus drivers and their assistants could be at risk of tuberculosis. The majority (85.7%) of bus drivers opened side window the whole day without precondition. Hearing tuberculosis related information from radio was a promoting factor for tuberculosis preventive measures among bus drivers. Tuberculosis preventive practices and knowledge of bus drivers seempositive (opportunities), despite their low risk perception (challenge). Using the opportunity, further empowering bus drivers to persuade passengers and assistants to open all the rest of the windows is needed.

  13. Exploring critical pathways for urban water management to identify robust strategies under deep uncertainties.

    PubMed

    Urich, Christian; Rauch, Wolfgang

    2014-12-01

    Long-term projections for key drivers needed in urban water infrastructure planning such as climate change, population growth, and socio-economic changes are deeply uncertain. Traditional planning approaches heavily rely on these projections, which, if a projection stays unfulfilled, can lead to problematic infrastructure decisions causing high operational costs and/or lock-in effects. New approaches based on exploratory modelling take a fundamentally different view. Aim of these is, to identify an adaptation strategy that performs well under many future scenarios, instead of optimising a strategy for a handful. However, a modelling tool to support strategic planning to test the implication of adaptation strategies under deeply uncertain conditions for urban water management does not exist yet. This paper presents a first step towards a new generation of such strategic planning tools, by combing innovative modelling tools, which coevolve the urban environment and urban water infrastructure under many different future scenarios, with robust decision making. The developed approach is applied to the city of Innsbruck, Austria, which is spatially explicitly evolved 20 years into the future under 1000 scenarios to test the robustness of different adaptation strategies. Key findings of this paper show that: (1) Such an approach can be used to successfully identify parameter ranges of key drivers in which a desired performance criterion is not fulfilled, which is an important indicator for the robustness of an adaptation strategy; and (2) Analysis of the rich dataset gives new insights into the adaptive responses of agents to key drivers in the urban system by modifying a strategy. Copyright © 2014 Elsevier Ltd. All rights reserved.

  14. Risk-taking on the road and in the mind: behavioural and neural patterns of decision making between risky and safe drivers.

    PubMed

    Ba, Yutao; Zhang, Wei; Peng, QiJia; Salvendy, Gavriel; Crundall, David

    2016-01-01

    Drivers' risk-taking is a key issue of road safety. This study explored individual differences in drivers' decision-making, linking external behaviours to internal neural activity, to reveal the cognitive mechanisms of risky driving. Twenty-four male drivers were split into two groups (risky vs. safe drivers) via the Drivier Behaviour Questionnaire-violation. The risky drivers demonstrated higher preference for the risky choices in the paradigms of Iowa Gambling Task and Balloon Analogue Risk Task. More importantly, the risky drivers showed lower amplitudes of feedback-related negativity (FRN) and loss-minus-gain FRN in both paradigms, which indicated their neural processing of error-detection. A significant difference of P300 amplitudes was also reported between groups, which indicated their neural processing of reward-evaluation and were modified by specific paradigm and feedback. These results suggested that the neural basis of risky driving was the decision patterns less revised by losses and more motivated by rewards. Risk-taking on the road is largely determined by inherent cognitive mechanisms, which can be indicated by the behavioural and neural patterns of decision-making. In this regard, it is feasible to quantize drivers’ riskiness in the cognitive stage before actual risky driving or accidents, and intervene accordingly.

  15. Scenarios for coastal vulnerability assessment

    USGS Publications Warehouse

    Nicholls, Robert J.; Woodroffe, Colin D.; Burkett, Virginia; Hay, John; Wong, Poh Poh; Nurse, Leonard; Wolanski, Eric; McLusky, Donald S.

    2011-01-01

    Coastal vulnerability assessments tend to focus mainly on climate change and especially on sea-level rise. Assessment of the influence of nonclimatic environmental change or socioeconomic change is less well developed and these drivers are often completely ignored. Given that the most profound coastal changes of the twentieth century due to nonclimate drivers are likely to continue through the twenty-first century, this is a major omission. It may result in not only overstating the importance of climate change but also overlooking significant interactions of climate change and other drivers. To support the development of policies relating to climate change and coastal management, integrated assessments of climatic change in coastal areas are required, including the effects of all the relevant drivers. This chapter explores the development of scenarios (or "plausible futures") of relevant climate and nonclimate drivers that can be used for coastal analysis, with an emphasis on the nonclimate drivers. It shows the importance of analyzing the impacts of climate change and sea-level rise in a broader context of coastal change and all its drivers. This will improve the analysis of impacts, key vulnerabilities, and adaptation needs and, hence, inform climate and coastal policy. Stakeholder engagement is important in the development of scenarios, and the underlying assumptions need to be explicit, transparent, and open to scientific debate concerning their uncertainties/realism and likelihood.

  16. Cooperative Vehicle–Highway Automation (CVHA) Technology : Simulation of Benefits and Operational Issues

    DOT National Transportation Integrated Search

    2017-03-01

    The past few years have witnessed a rapidly growing market in assistive driving technologies, designed to improve safety and operations by supporting driver performance. Often referred to as cooperative vehiclehighway automation (CVHA) systems, th...

  17. SmartPark Technology Demonstration Project, Phase II: Final Report : Technology Brief

    DOT National Transportation Integrated Search

    2018-05-01

    In 2000, the National Transportation Safety Board recommended that the Federal Motor Carrier Safety Administration (FMCSA) create a guide to inform truck drivers about locations and availability of parking. In 2002, the Federal Highway Administration...

  18. Obstacles to engaging in young driver licensing: Perspectives of parents.

    PubMed

    Naz, Sehana; Scott-Parker, Bridie

    2017-02-01

    Young novice drivers remain at greater risk of injury and death despite a wealth of interventions including graduated driver licensing (GDL) programs. The key to implementing safer practices inherent in GDL appears to lie with optimising the role of parents. This qualitative research explored the parent's perspectives of obstacles to engaging in the driver licensing process within a GDL program. Parents also shared advice on what they found helpful, and where relevant, recommended changes in the process to enable safer practices for young drivers. Twenty-three parents (aged 35-60 years, M=49.52, SD=8.01, 11 males) participated in semi-structured interviews regarding licensing experiences with their young driver children. The young drivers included learner (n=11), provisional (restricted/intermediate) (n=9) and open (unrestricted/full) licence drivers (n=3), ranging from 16 to 24 years (M=18.04, SD=2.21, 13 males). Content analysis revealed that most obstacles were encountered at the learner licensing phase, with the parent-reported difficult temperament of the learner driver the most prominent. Unsurprisingly, advice to other parents to be patient and remain calm featured heavily during the same phase. Anxiety from not having control of the vehicle was another obstacle at the learner phase, translating to anxieties for child safety in the early stages of provisional driving. Recommendations for the current GDL included more rigorous road rule testing, with general support for the program, professional driver training at learner and provisional stages facilitated parental engagement through the licensing phases. The findings overwhelmingly suggest a need for parents to be educated regarding their importance in, and of, the driver licensing process, and the efficacy of their instruction, content and practices. Copyright © 2016 Elsevier Ltd. All rights reserved.

  19. A systematic study on drug-response associated genes using baseline gene expressions of the Cancer Cell Line Encyclopedia

    NASA Astrophysics Data System (ADS)

    Liu, Xiaoming; Yang, Jiasheng; Zhang, Yi; Fang, Yun; Wang, Fayou; Wang, Jun; Zheng, Xiaoqi; Yang, Jialiang

    2016-03-01

    We have studied drug-response associated (DRA) gene expressions by applying a systems biology framework to the Cancer Cell Line Encyclopedia data. More than 4,000 genes are inferred to be DRA for at least one drug, while the number of DRA genes for each drug varies dramatically from almost 0 to 1,226. Functional enrichment analysis shows that the DRA genes are significantly enriched in genes associated with cell cycle and plasma membrane. Moreover, there might be two patterns of DRA genes between genders. There are significantly shared DRA genes between male and female for most drugs, while very little DRA genes tend to be shared between the two genders for a few drugs targeting sex-specific cancers (e.g., PD-0332991 for breast cancer and ovarian cancer). Our analyses also show substantial difference for DRA genes between young and old samples, suggesting the necessity of considering the age effects for personalized medicine in cancers. Lastly, differential module and key driver analyses confirm cell cycle related modules as top differential ones for drug sensitivity. The analyses also reveal the role of TSPO, TP53, and many other immune or cell cycle related genes as important key drivers for DRA network modules. These key drivers provide new drug targets to improve the sensitivity of cancer therapy.

  20. FTTH: the overview of existing technologies

    NASA Astrophysics Data System (ADS)

    Nowak, Dawid; Murphy, John

    2005-06-01

    The growing popularity of the Internet is the key driver behind the development of new access methods which would enable a customer to experience a true broadband. Amongst various technologies, the access methods based on the optical fiber are getting more and more attention as they offer the ultimate solution in delivering different services to the customers' premises. Three different architectures have been proposed that facilitate the roll out of Fiber-to-the-Home (FTTH) infrastructure. Point-to-point Ethernet networks are the most straightforward and already matured solution. Different flavors of Passive Optical Networks (PONs) with Time Division Multiplexing Access (TDMA) are getting more widespread as necessary equipment is becoming available on the market. The third main contender are PONs withWavelength DivisionMultiplexing Access (WDMA). Although still in their infancy, the laboratory tests show that they have many advantages over present solutions. In this paper we show a brief comparison of these three access methods. In our analysis the architecture of each solution is presented. The applicability of each system is looked at from different viewpoint and their advantages and disadvantages are highlighted.

  1. Enhancing reading abilities of learners with intellectual impairments through computer technology

    PubMed Central

    Warnick, Albert M.

    2017-01-01

    Background Developments in the teaching of children with disabilities support pedagogy that emphasises learners’ strengths as opposed to their assumed deficiencies. Educators and mediators who advocate this view continually strive for tools and methodologies that enhance learner participation in academic environments. Computer technology is one of the tools recognised for its potential to enrich learning experiences of learners with an intellectual impairment. Objectives We sought to assess the influence of text-to-speech stories on the reading ability of intellectually challenged learners. Method A qualitative action research study that involves learners at a special school in Cape Town, South Africa. Pre- and post-test data of the reading performance of learners are analysed with a focus on how they demonstrate change. Results Although no claims can be made about the explicit influence on reading performance, computer-assisted learning has the potential in isolating reading processes that classroom-based interventions can address. In addition, computers enhance motivation and enthusiasm to learn. Conclusion A need for education based on inclusion and positive differentiation remains the key driver in any educational interventions. PMID:28951849

  2. Liquidity, Technological Opportunities, and the Stage Distribution of Venture Capital Investments.

    PubMed

    Lahr, Henry; Mina, Andrea

    2014-06-01

    This paper explores the determinants of the stage distribution of European venture capital investments from 1990 to 2011. Consistent with liquidity risk theory, we find that the likelihood of investing in earlier stages increases relative to all private equity investments during liquidity crisis years. While liquidity is the main driver of acquisition investments and, to some extent, of expansion financings, technological opportunities are overall the main driver of early and late stage venture capital investments. In contrast to the dotcom crash, the recent financial crisis negatively affected the relative likelihood of expansion investments, but not of early and late stage investments.

  3. Liquidity, Technological Opportunities, and the Stage Distribution of Venture Capital Investments

    PubMed Central

    Lahr, Henry; Mina, Andrea

    2014-01-01

    This paper explores the determinants of the stage distribution of European venture capital investments from 1990 to 2011. Consistent with liquidity risk theory, we find that the likelihood of investing in earlier stages increases relative to all private equity investments during liquidity crisis years. While liquidity is the main driver of acquisition investments and, to some extent, of expansion financings, technological opportunities are overall the main driver of early and late stage venture capital investments. In contrast to the dotcom crash, the recent financial crisis negatively affected the relative likelihood of expansion investments, but not of early and late stage investments. PMID:26166906

  4. Coevolution of yeast mannan digestion: Convergence of the civilized human diet, distal gut microbiome, and host immunity

    PubMed Central

    Abbott, D Wade; Martens, Eric C; Gilbert, Harry J; Cuskin, Fiona; Lowe, Elisabeth C

    2015-01-01

    The complex carbohydrates accessible to the distal gut microbiota (DGM) are key drivers in determining the structure of this ecosystem. Typically, plant cell wall polysaccharides and recalcitrant starch (i.e. dietary fiber), in addition to host glycans are considered the primary nutrients for the DGM; however, we recently demonstrated that α-mannans, highly branched polysaccharides that decorate the surface of yeast, are also nutrients for several members of Bacteroides spp. This relationship suggests that the advent of yeast in contemporary food technologies and the colonization of the intestine by endogenous fungi have roles in microbiome structure and function. Here we discuss the process of yeast mannan metabolism, and the intersection between various sources of intestinal fungi and their roles in recognition by the host innate immune system. PMID:26440374

  5. Power subsystem automation study

    NASA Technical Reports Server (NTRS)

    Imamura, M. S.; Moser, R. L.; Veatch, M.

    1983-01-01

    Generic power-system elements and their potential faults are identified. Automation functions and their resulting benefits are defined and automation functions between power subsystem, central spacecraft computer, and ground flight-support personnel are partitioned. All automation activities were categorized as data handling, monitoring, routine control, fault handling, planning and operations, or anomaly handling. Incorporation of all these classes of tasks, except for anomaly handling, in power subsystem hardware and software was concluded to be mandatory to meet the design and operational requirements of the space station. The key drivers are long mission lifetime, modular growth, high-performance flexibility, a need to accommodate different electrical user-load equipment, onorbit assembly/maintenance/servicing, and potentially large number of power subsystem components. A significant effort in algorithm development and validation is essential in meeting the 1987 technology readiness date for the space station.

  6. It Comes With the Job: Work Organizational, Job Design, and Self-Regulatory Barriers to Improving the Health Status of Train Drivers.

    PubMed

    Naweed, Anjum; Chapman, Janine; Allan, Matthew; Trigg, Joshua

    2017-03-01

    This study aimed to examine the impacts of key barriers to improving the occupational health status of Australian train drivers. From May to June, 2015, five semi-structured qualitative focus groups were conducted with 29 train drivers from South Australian, Victorian, and New South Wales-based rail organizations in Australia. Occupational health was impeded by multiple barriers regarding sleep (patterns/fatigue), diet (planning/context), mental health (occupational stress), rostering (low autonomy), sedentary time, low fitness motivation, and family/social life conflicts. Work organizational barriers included communication issues, low organizational support, and existing social norms. Job design barriers included rostering, fatigue, stimulant reliance, and family/social life imbalances. Self-regulatory barriers included dietary and exercise patterns habits and patterns. Occupational health interventions for Australian train drivers must address work organizational, job design, and self-regulatory barriers to healthier lifestyle behaviors.

  7. Assessing communication as one of the drivers of urban resilience to weather extremes.

    NASA Astrophysics Data System (ADS)

    Vicari, Rosa; Schertzer, Daniel

    2016-04-01

    The quality of science and technology communication has become more challenging due to the fact that access to information has hugely increased in terms of variety and quantity. This is a consequence of different factors, among others the development of public relations by research institutes and the pervasive role of digital media (Bucchi 2013; Trench 2008). A key question is how can we objectively assess science and technology communication? Relatively few studies have been dedicated to the definition of pertinent indicators and standards (Neresini and Bucchi 2011). This research aims to understand how communication strategies, addressed to the general public, can optimise the impact of research findings in hydrology for resilient cities and how this can be assessed. Indeed urban resilience to extreme weather events relies both on engineering solutions and increased awareness of urban communities as it was highlighted by the FP7 SMARTesT project and the experiences carried out in the framework of TOMACS (Tokyo Metropolitan Area Convective Studies for Resilient Cities) and CASA (Engineering Research Center for Collaborative Adaptative Sensing of the Atmosphere, supported by the U.S. National Science Foundation). Communication assessment should be included in an alternative approach to evaluate urban resilience to weather extremes. Various qualitative and quantitative methods to monitor communication exist. According to this study, resilience indicators shouldn't only consider communication infrastructures but should also assess communication processes and their interactions with other resilience drivers; furthermore quantitative variables are considered as particularly relevant. Last, but not least, interesting inputs are provided by those case studies that exploit resilience assessment campaigns as an opportunity to practice participatory communication. This research is being led in the framework of the Chair Hydrology for Resilient Cities, co-founded by Veolia, Fondation des Ponts, and École des Ponts ParisTech.

  8. Process-based Cost Estimation for Ramjet/Scramjet Engines

    NASA Technical Reports Server (NTRS)

    Singh, Brijendra; Torres, Felix; Nesman, Miles; Reynolds, John

    2003-01-01

    Process-based cost estimation plays a key role in effecting cultural change that integrates distributed science, technology and engineering teams to rapidly create innovative and affordable products. Working together, NASA Glenn Research Center and Boeing Canoga Park have developed a methodology of process-based cost estimation bridging the methodologies of high-level parametric models and detailed bottoms-up estimation. The NASA GRC/Boeing CP process-based cost model provides a probabilistic structure of layered cost drivers. High-level inputs characterize mission requirements, system performance, and relevant economic factors. Design alternatives are extracted from a standard, product-specific work breakdown structure to pre-load lower-level cost driver inputs and generate the cost-risk analysis. As product design progresses and matures the lower level more detailed cost drivers can be re-accessed and the projected variation of input values narrowed, thereby generating a progressively more accurate estimate of cost-risk. Incorporated into the process-based cost model are techniques for decision analysis, specifically, the analytic hierarchy process (AHP) and functional utility analysis. Design alternatives may then be evaluated not just on cost-risk, but also user defined performance and schedule criteria. This implementation of full-trade study support contributes significantly to the realization of the integrated development environment. The process-based cost estimation model generates development and manufacturing cost estimates. The development team plans to expand the manufacturing process base from approximately 80 manufacturing processes to over 250 processes. Operation and support cost modeling is also envisioned. Process-based estimation considers the materials, resources, and processes in establishing cost-risk and rather depending on weight as an input, actually estimates weight along with cost and schedule.

  9. Income and Technology as Drivers of Australian Healthcare Expenditures.

    PubMed

    You, Xiaohui; Okunade, Albert A

    2017-07-01

    The roles of income and technology as the major determinants of aggregate healthcare expenditure (HEXP) continue to interest economists and health policy researchers. Concepts and measures of medical technologies remain complex; however, income (on the demand side) and technology (on the supply side) are important drivers of HEXP. This paper presents analysis of Australia's HEXP, using time-series econometrics modeling techniques applied to 1971-2011 annual aggregate data. Our work fills two important gaps in the literature. First, we model the determinants of Australia's HEXP using the latest and longest available data series. Second, this novel study investigates several alternative technology proxies (input and output measures), including economy-wide research and development expenditures, hospital research expenditures, mortality rate, and two technology indexes based on medical devices. We then apply the residual component method and the technology proxy approach to quantify the technology effects on HEXP. Our empirical results suggest that Australian aggregate healthcare is a normal good and a technical necessity with the income elasticity estimates ranging from 0.51 to 0.97, depending on the model. The estimated technology effects on HEXP falling in the 0.30-0.35 range and mimicking those in the literature using the US data, reinforce the global spread of healthcare technology. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  10. Incorporating driver behaviors into connected and automated vehicle simulation.

    DOT National Transportation Integrated Search

    2016-05-24

    The adoption of connected vehicle (CV) technology is anticipated at various levels of development and deployment over the next decade. One primary challenge with these new technologies is the lack of platform to enable a robust and reliable evaluatio...

  11. Automatic vehicle identification technology applications to toll collection services

    DOT National Transportation Integrated Search

    1997-01-01

    Intelligent transportation systems technologies are being developed and applied through transportation systems in the United States. An example of this type of innovation can be seen on toll roads where a driver is required to deposit a toll in order...

  12. Water conservation behavior in Australia.

    PubMed

    Dolnicar, Sara; Hurlimann, Anna; Grün, Bettina

    2012-08-30

    Ensuring a nation's long term water supply requires the use of both supply-sided approaches such as water augmentation through water recycling, and demand-sided approaches such as water conservation. Conservation behavior can only be increased if the key drivers of such behavior are understood. The aim of this study is to reveal the main drivers from a comprehensive pool of hypothesized factors. An empirical study was conducted with 3094 Australians. Data was analyzed using multivariate linear regression analysis and decision trees to determine which factors best predict self-reported water conservation behavior. Two key factors emerge: high level of pro-environmental behavior; and pro-actively seeking out information about water. A number of less influential factors are also revealed. Public communication strategy implications are derived. Copyright © 2012 Elsevier Ltd. All rights reserved.

  13. Capacity Building for Entrepreneurship Education: The Challenge for the Developing Nations

    ERIC Educational Resources Information Center

    Eze, John F.; Nwali, Anthony C.

    2012-01-01

    Entrepreneurship is one of the key drivers for development in any society. The level of awareness of individual members, of a society, of their capacity to contribute to the economic, social and political development of their society is a key factor in development. A process of creating this self-awareness and the development of individual…

  14. Demonstration of an Environmentally Benign and Reduced Corrosion Runway Deicing Fluid

    DTIC Science & Technology

    2011-01-01

    43201 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS(ES) Enviromental Security Technology...laboratory to the airfields and airports across the country. Users may express concern because the Battelle-RDFs are new and they may have...airfield anti-icing and deicing at WPAFB. 1.3 REGULATORY DRIVERS There are several drivers for implementing a new , more environmentally friendly

  15. Key drivers for market penetration of biosimilars in Europe.

    PubMed

    Rémuzat, Cécile; Dorey, Julie; Cristeau, Olivier; Ionescu, Dan; Radière, Guerric; Toumi, Mondher

    2017-01-01

    Background & Objectives : Potential drivers and barriers of biosimilar uptake were mainly analysed through qualitative approaches. The study objective was to conduct a quantitative analysis and identify drivers of biosimilar uptake of all available biosimilars in the European Union (EU). Methods : A three-step process was established to identify key drivers for the uptake of biosimilars in the top 10 EU member states (MS) pharmaceutical markets (Belgium, France, Germany, Greece, Hungary, Italy, Poland, Spain, Sweden, and the UK): (1) literature review to identify incentive policies in place to enhance biosimilars adoption; (2) assessment of biosimilar market dynamics based on database analysis; (3) regression model analysis on price using the following explicative variables: incentive policies; price difference between the biosimilar and the originator product; distribution channel; generic uptake and generic price cut; pharmaceutical expenditure per capita; and market competition. Results : At the study cut-off date, 20 biosimilars were available on the market. Incentive policies applied to biosimilars were found to be heterogeneous across countries, and uptakes of biosimilars were also very heterogeneous between different therapeutic classes and countries. Results from the model demonstrated that incentive policies and the date of first biosimilar market entry were correlated to biosimilar uptake. Pharmaceutical expenditure per capita and the highest generic uptake were inversely correlated with biosimilar uptake. Average generic price discount over originator and the number of biosimilars showed a trend toward statistical significance for correlation with biosimilar uptake, but did not reach the significance threshold. Biosimilar price discount over original biologic price, the number of analogues, and the distribution channel were not correlated with the biosimilar uptake. Conclusions : Understanding drivers of biosimilar uptake becomes a critical issue to inform policy decision-makers. This study showed that incentive policies to enhance uptake remain an important driver of biosimilar penetration, while biosimilar price discounts have no impact. Future research is warranted when the biosimilar market gains maturity.

  16. Key drivers for market penetration of biosimilars in Europe

    PubMed Central

    Rémuzat, Cécile; Dorey, Julie; Cristeau, Olivier; Ionescu, Dan; Radière, Guerric; Toumi, Mondher

    2017-01-01

    ABSTRACT Background & Objectives: Potential drivers and barriers of biosimilar uptake were mainly analysed through qualitative approaches. The study objective was to conduct a quantitative analysis and identify drivers of biosimilar uptake of all available biosimilars in the European Union (EU). Methods: A three-step process was established to identify key drivers for the uptake of biosimilars in the top 10 EU member states (MS) pharmaceutical markets (Belgium, France, Germany, Greece, Hungary, Italy, Poland, Spain, Sweden, and the UK): (1) literature review to identify incentive policies in place to enhance biosimilars adoption; (2) assessment of biosimilar market dynamics based on database analysis; (3) regression model analysis on price using the following explicative variables: incentive policies; price difference between the biosimilar and the originator product; distribution channel; generic uptake and generic price cut; pharmaceutical expenditure per capita; and market competition. Results: At the study cut-off date, 20 biosimilars were available on the market. Incentive policies applied to biosimilars were found to be heterogeneous across countries, and uptakes of biosimilars were also very heterogeneous between different therapeutic classes and countries. Results from the model demonstrated that incentive policies and the date of first biosimilar market entry were correlated to biosimilar uptake. Pharmaceutical expenditure per capita and the highest generic uptake were inversely correlated with biosimilar uptake. Average generic price discount over originator and the number of biosimilars showed a trend toward statistical significance for correlation with biosimilar uptake, but did not reach the significance threshold. Biosimilar price discount over original biologic price, the number of analogues, and the distribution channel were not correlated with the biosimilar uptake. Conclusions: Understanding drivers of biosimilar uptake becomes a critical issue to inform policy decision-makers. This study showed that incentive policies to enhance uptake remain an important driver of biosimilar penetration, while biosimilar price discounts have no impact. Future research is warranted when the biosimilar market gains maturity. PMID:28265349

  17. Flood risk (d)evolution: Disentangling key drivers of flood risk change with a retro-model experiment.

    PubMed

    Zischg, Andreas Paul; Hofer, Patrick; Mosimann, Markus; Röthlisberger, Veronika; Ramirez, Jorge A; Keiler, Margreth; Weingartner, Rolf

    2018-05-19

    Flood risks are dynamically changing over time. Over decades and centuries, the main drivers for flood risk change are influenced either by perturbations or slow alterations in the natural environment or, more importantly, by socio-economic development and human interventions. However, changes in the natural and human environment are intertwined. Thus, the analysis of the main drivers for flood risk changes requires a disentangling of the individual risk components. Here, we present a method for isolating the individual effects of selected drivers of change and selected flood risk management options based on a model experiment. In contrast to purely synthetic model experiments, we built our analyses upon a retro-model consisting of several spatio-temporal stages of river morphology and settlement structure. The main advantage of this approach is that the overall long-term dynamics are known and do not have to be assumed. We used this model setup to analyse the temporal evolution of the flood risk, for an ex-post evaluation of the key drivers of change, and for analysing possible alternative pathways for flood risk evolution under different governance settings. We showed that in the study region the construction of lateral levees and the consecutive river incision are the main drivers for decreasing flood risks over the last century. A rebound effect in flood risk can be observed following an increase in settlements since the 1960s. This effect is not as relevant as the river engineering measures, but it will become increasingly relevant in the future with continued socio-economic growth. The presented approach could provide a methodological framework for studying pathways for future flood risk evolvement and for the formulation of narratives for adapting governmental flood risk strategies to the spatio-temporal dynamics in the built environment. Copyright © 2018 Elsevier B.V. All rights reserved.

  18. Speech-based E-mail and driver behavior: effects of an in-vehicle message system interface.

    PubMed

    Jamson, A Hamish; Westerman, Stephen J; Hockey, G Robert J; Carsten, Oliver M J

    2004-01-01

    As mobile office technology becomes more advanced, drivers have increased opportunity to process information "on the move." Although speech-based interfaces can minimize direct interference with driving, the cognitive demands associated with such systems may still cause distraction. We studied the effects on driving performance of an in-vehicle simulated "E-mail" message system; E-mails were either system controlled or driver controlled. A high-fidelity, fixed-base driving simulator was used to test 19 participants on a car-following task. Virtual traffic scenarios varying in driving demand. Drivers compensated for the secondary task by adopting longer headways but showed reduced anticipation of braking requirements and shorter time to collision. Drivers were also less reactive when processing E-mails, demonstrated by a reduction in steering wheel inputs. In most circumstances, there were advantages in providing drivers with control over when E-mails were opened. However, during periods without E-mail interaction in demanding traffic scenarios, drivers showed reduced braking anticipation. This may be a result of increased cognitive costs associated with the decision making process when using a driver-controlled interface when the task of scheduling E-mail acceptance is added to those of driving and E-mail response. Actual or potential applications of this research include the design of speech-based in-vehicle messaging systems.

  19. Poly-Si TFTs integrated gate driver circuit with charge-sharing structure

    NASA Astrophysics Data System (ADS)

    Chen, Meng; Lei, Jiefeng; Huang, Shengxiang; Liao, Congwei; Deng, Lianwen

    2017-06-01

    A p-type low-temperature poly-Si thin film transistors (LTPS TFTs) integrated gate driver using 2 non-overlapped clocks is proposed. This gate driver features charge-sharing structure to turn off buffer TFT and suppresses voltage feed-through effects. It is analyzed that the conventional gate driver suffers from waveform distortions due to voltage uncertainty of internal nodes for the initial period. The proposed charge-sharing structure also helps to suppress the unexpected pulses during the initialization phases. The proposed gate driver shows a simple circuit, as only 6 TFTs and 1 capacitor are used for single-stage, and the buffer TFT is used for both pulling-down and pulling-up of output electrode. Feasibility of the proposed gate driver is proven through detailed analyses. Investigations show that voltage bootrapping can be maintained once the bootrapping capacitance is larger than 0.8 pF, and pulse of gate driver outputs can be reduced to 5 μs. The proposed gate driver can still function properly with positive {V}{TH} shift within 0.4 V and negative {V}{TH} shift within -1.2 V and it is robust and promising for high-resolution display. Project supported by the Science and Technology Project of Hunan Province, China (No. 2015JC3401)

  20. Efficacy of side air bags in reducing driver deaths in driver-side collisions.

    PubMed

    Braver, Elisa R; Kyrychenko, Sergey Y

    2004-03-15

    Side air bags, a relatively new technology designed to protect the head and/or torso in side-impact collisions, are becoming increasingly common in automobiles. Their efficacy in preventing US driver deaths among cars struck on the near (driver's) side was examined using data from the Fatality Analysis Reporting System and the General Estimates System. Risk ratios for driver death per nearside collision during 1999-2001 were computed for head/torso and torso-only side air bags in cars from model years 1997-2002, relative to cars without side air bags. Confounding was addressed by adjusting nearside risk ratios for front- and rear-impact mortality, which is unaffected by side air bags. Risk ratios were 0.55 (95% confidence interval: 0.43, 0.71) for head/torso air bags and 0.89 (95% confidence interval: 0.79, 1.01) for torso-only air bags. Risk was reduced when cars with head/torso air bags were struck by cars/minivans (significant) or pickup trucks/sport utility vehicles (nonsignificant). Risk was reduced in two-vehicle collisions and among male drivers and drivers aged 16-64 years. Protective effects associated with torso-only air bags were observed in single-vehicle crashes and among male and 16- to 64-year-old drivers. Head/torso side air bags appear to be very effective in reducing nearside driver deaths, whereas torso-only air bags appear less protective.

  1. An exploratory study of long-haul truck drivers' secondary tasks and reasons for performing them.

    PubMed

    Iseland, Tobias; Johansson, Emma; Skoog, Siri; Dåderman, Anna M

    2018-08-01

    Research on drivers has shown how certain visual-manual secondary tasks, unrelated to driving, increase the risk of being involved in crashes. The purpose of the study was to investigate (1) if long-haul truck drivers in Sweden engage in secondary tasks while driving, what tasks are performed and how frequently, (2) the drivers' self-perceived reason/s for performing them, and (3) if psychological factors might reveal reasons for their engaging in secondary tasks. The study comprised 13 long-haul truck drivers and was conducted through observations, interviews, and questionnaires. The drivers performed secondary tasks, such as work environment related "necessities" (e.g., getting food and/or beverages from the refrigerator/bag, eating, drinking, removing a jacket, face rubbing, and adjusting the seat), interacting with a mobile phone/in-truck technology, and doing administrative tasks. The long-haul truck drivers feel bored and use secondary tasks as a coping strategy to alleviate boredom/drowsiness, and for social interaction. The higher number of performed secondary tasks could be explained by lower age, shorter driver experience, less openness to experience, lower honesty-humility, lower perceived stress, lower workload, and by higher health-related quality of life. These explanatory results may serve as a starting point for further studies on large samples to develop a safer and healthier environment for long-haul truck drivers. Copyright © 2018. Published by Elsevier Ltd.

  2. Essential Power Systems Workshop - OEM Perspective

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bill Gouse

    2001-12-12

    In California, idling is largely done for climate control. This suggests that climate control devices alone could be used to reduce idling. Line-haul truck drivers surveyed require an average of 4-6 kW of power for a stereo, CB radio, light, refrigerator, and climate control found in the average truck. More power may likely be necessary for peak power demands. The amount of time line-haul trucks reported to have stopped is between 25 and 30 hours per week. It was not possible to accurately determine from the pilot survey the location, purpose, and duration of idling. Consulting driver logs or electronicallymore » monitoring trucks could yield more accurate data, including seasonal and geographic differences. Truck drivers were receptive to idling alternatives. Two-thirds of truck drivers surveyed support a program to reduce idling. Two-thirds of drivers reported they would purchase idling reduction technologies if the technology yielded a payback period of two years or less. Willingness to purchase auxiliary power units appears to be higher for owner-operators than for company drivers. With a 2-year payback period, 82% of owner- operators would be willing to buy an idle- reducing device, while 63% of company drivers thought their company would do the same. Contact with companies is necessary to discern whether this difference between owner- operators and companies is true or simply due to the perception of the company drivers. Truck stops appear to be a much more attractive option for electrification than rest areas by a 48% to 21% margin. Much of this discrepancy may be due to perceived safety problems with rest areas. This survey did not properly differentiate between using these areas for breaks or overnight. The next, full survey will quantify where the truck drivers are staying overnight, where they go for breaks, and the duration of time they spend at each place. The nationwide survey, which is in progress, will indicate how applicable the results are to the US in general. In addition to the survey, we believe data loggers and focus groups will be necessary to collect the idling duration and location data necessary to compare auxiliary power units to truck stop electrification. Focus groups are recommended to better understand the driver response to APUs and electrification. The appearance and perception of the new systems will need further clarification, which could be accomplished with a demonstration for truck drivers.« less

  3. Design and cost drivers in 2-D braiding

    NASA Technical Reports Server (NTRS)

    Morales, Alberto

    1993-01-01

    Fundamentally, the braiding process is a highly efficient, low cost method for combining single yarns into circumferential shapes, as evidenced by the number of applications for continuous sleeving. However, this braiding approach cannot fully demonstrate that it can drastically reduce the cost of complex shape structural preforms. Factors such as part geometry, machine design and configuration, materials used, and operating parameters are described as key cost drivers and what is needed to minimize their effect on elevating the cost of structural braided preforms.

  4. Driving with Diabetes: Precaution, Not Prohibition, Is the Proper Approach

    PubMed Central

    Kohrman, Daniel B.

    2013-01-01

    Safety issues posed by driving with diabetes are primarily related to severe hypoglycemia, yet some public authorities rely on categorical restrictions on drivers with diabetes. This approach is misguided. Regulation of all drivers with diabetes, or all drivers using insulin, ignores the diversity of people with diabetes and fails to focus on the subpopulation posing the greatest risk. Advances in diabetes care technology and understanding of safety consequences of diabetes have expanded techniques available to limit risks of driving with diabetes. New means of insulin administration and blood glucose monitoring offer greater ease of anticipating and preventing hypoglycemia, and thus, limit driving risk for persons with diabetes. So too do less sophisticated steps taken by people with diabetes and the health care professionals they consult. These include adoption and endorsement of safety-sensitive behaviors, such as testing before a drive and periodic testing on longer trips. Overall, and in most individual cases, driving risks for persons with diabetes are less than those routinely tolerated by our society. Examples include freedom to drive in dangerous conditions and lax regulation of drivers in age and medical cohorts with elevated overall rates of driving mishaps. Data linking specific diabetes symptoms or features with driving risk are quite uncertain. Hence, there is much to recommend: a focus on technological advances, human precautions, and identifying individuals with diabetes with a specific history of driving difficulty. By contrast, available evidence does not support unfocused regulation of all or most drivers with diabetes. PMID:23566992

  5. Scenarios to prioritize observing activities on the North Slope, Alaska in the context of resource development, climate change and socio-economic uncertainties

    NASA Astrophysics Data System (ADS)

    Lee, O. A.; Eicken, H.; Payne, J. F.; Lassuy, D.

    2014-12-01

    The North Slope of Alaska is experiencing rapid changes in response to interacting climate and socioeconomic drivers. The North Slope Science Initiative (NSSI) is using scenarios as a tool to identify plausible, spatially explicit future states of resource extraction activities on the North Slope and adjacent seas through the year 2040. The objective of the scenarios process is to strategically assess research and monitoring needs on the North Slope. The participatory scenarios process involved stakeholder input (including Federal, State, local, academic, industry and non-profit representatives) to identify key drivers of change related to resource extraction activities on the North Slope. While climate change was identified as a key driver in the biophysical system, economic drivers related to oil and gas development were also important. Expert-reviewed informational materials were developed to help stakeholders obtain baseline knowledge and stimulate discussions about interactions between drivers, knowledge gaps and uncertainties. Map-based scenario products will allow mission-oriented agencies to jointly explore where to prioritize research investments and address risk in a complex, changing environment. Scenarios consider multidecadal timescales. However, tracking of indicator variables derived from scenarios can lead to important insights about the trajectory of the North Slope social-environmental system and inform management decisions to reduce risk on much shorter timescales. The inclusion of stakeholders helps provide a broad spectrum of expert viewpoints necessary for considering the range of plausible scenarios. A well-defined focal question, transparency in the participation process and continued outreach about the utility and limitations of scenarios are also important components of the scenarios process.

  6. Cost drivers for breast, lung, and colorectal cancer care in a commercially insured population over a 6-month episode: an economic analysis from a health plan perspective.

    PubMed

    Sagar, Bhuvana; Lin, Yu Shen; Castel, Liana D

    2017-10-01

    In the absence of clinical data, accurate identification of cost drivers is needed for economic comparison in an alternate payment model. From a health plan perspective using claims data in a commercial population, the objective was to identify and quantify the effects of cost drivers in economic models of breast, lung, and colorectal cancer costs over a 6-month episode following initial chemotherapy. This study analyzed claims data from 9,748 Cigna beneficiaries with diagnosis of breast, lung, and colorectal cancer following initial chemotherapy from January 1, 2014 to December 31, 2015. We used multivariable regression models to quantify the impact of key factors on cost during the initial 6-month cancer care episode. Metastasis, facility provider affiliation, episode risk group (ERG) risk score, and radiation were cost drivers for all three types of cancer (breast, lung, and colorectal). In addition, younger age (p < .0001) and human epidermal growth factor receptor-2 oncogene overexpression (HER2+)-directed therapy (p < .0001) were associated with higher costs in breast cancer. Younger age (p < .0001) and female gender (p < .0001) were also associated with higher costs in colorectal cancer. Metastasis was also associated with 50% more hospital admissions and increased hospital length of stay (p < .001) in all three cancers over the 6-month episode duration. Chemotherapy and supportive drug therapies accounted for the highest proportion (48%) of total medical costs among beneficiaries observed. Value-based reimbursement models in oncology should appropriately account for key cost drivers. Although claims-based methodologies may be further augmented with clinical data, this study recommends adjusting for the factors identified in these models to predict costs in breast, lung, and colorectal cancers.

  7. Gigascale Silicon Photonic Transmitters Integrating HBT-based Carrier-injection Electroabsorption Modulator Structures

    NASA Astrophysics Data System (ADS)

    Fu, Enjin

    Demand for more bandwidth is rapidly increasing, which is driven by data intensive applications such as high-definition (HD) video streaming, cloud storage, and terascale computing applications. Next-generation high-performance computing systems require power efficient chip-to-chip and intra-chip interconnect yielding densities on the order of 1Tbps/cm2. The performance requirements of such system are the driving force behind the development of silicon integrated optical interconnect, providing a cost-effective solution for fully integrated optical interconnect systems on a single substrate. Compared to conventional electrical interconnect, optical interconnects have several advantages, including frequency independent insertion loss resulting in ultra wide bandwidth and link latency reduction. For high-speed optical transmitter modules, the optical modulator is a key component of the optical I/O channel. This thesis presents a silicon integrated optical transmitter module design based on a novel silicon HBT-based carrier injection electroabsorption modulator (EAM), which has the merits of wide optical bandwidth, high speed, low power, low drive voltage, small footprint, and high modulation efficiency. The structure, mechanism, and fabrication of the modulator structure will be discussed which is followed by the electrical modeling of the post-processed modulator device. The design and realization of a 10Gbps monolithic optical transmitter module integrating the driver circuit architecture and the HBT-based EAM device in a 130nm BiCMOS process is discussed. For high power efficiency, a 6Gbps ultra-low power driver IC implemented in a 130nm BiCMOS process is presented. The driver IC incorporates an integrated 27-1 pseudo-random bit sequence (PRBS) generator for reliable high-speed testing, and a driver circuit featuring digitally-tuned pre-emphasis signal strength. With outstanding drive capability, the driver module can be applied to a wide range of carrier injection modulators and light-emitting diodes (LED) with drive voltage requirements below 1.5V. Measurement results show an optical link based on a 70MHz red LED work well at 300Mbps by using the pre-emphasis driver module. A traveling wave electrode (TWE) modulator structure is presented, including a novel design methodology to address process limitations imposed by a commercial silicon fabrication technology. Results from 3D full wave EM simulation demonstrate the application of the design methodology to achieve specifications, including phase velocity matching, insertion loss, and impedance matching. Results show the HBT-based TWE-EAM system has the bandwidth higher than 60GHz.

  8. Incorporating a Socio-Ecological-Technological Systems (SETS) perspective into the adaptive management framework

    EPA Science Inventory

    Incorporating a social-ecological-technological systems (SETS) perspective to the adaptive management process requires that stakeholders and managers conceptualize restoration projects as part of coupled human and natural systems and assess underlying social drivers and accrued b...

  9. Design and characterization of a high-power ultrasound driver with ultralow-output impedance

    NASA Astrophysics Data System (ADS)

    Lewis, George K.; Olbricht, William L.

    2009-11-01

    We describe a pocket-sized ultrasound driver with an ultralow-output impedance amplifier circuit (less than 0.05 Ω) that can transfer more than 99% of the voltage from a power supply to the ultrasound transducer with minimal reflections. The device produces high-power acoustical energy waves while operating at lower voltages than conventional ultrasound driving systems because energy losses owing to mismatched impedance are minimized. The peak performance of the driver is measured experimentally with a PZT-4, 1.54 MHz, piezoelectric ceramic, and modeled using an adjusted Mason model over a range of transducer resonant frequencies. The ultrasound driver can deliver a 100 Vpp (peak to peak) square-wave signal across 0-8 MHz ultrasound transducers in 5 ms bursts through continuous wave operation, producing acoustic powers exceeding 130 W. Effects of frequency, output impedance of the driver, and input impedance of the transducer on the maximum acoustic output power of piezoelectric transducers are examined. The small size, high power, and efficiency of the ultrasound driver make this technology useful for research, medical, and industrial ultrasonic applications.

  10. Design and characterization of a high-power ultrasound driver with ultralow-output impedance.

    PubMed

    Lewis, George K; Olbricht, William L

    2009-11-01

    We describe a pocket-sized ultrasound driver with an ultralow-output impedance amplifier circuit (less than 0.05 ohms) that can transfer more than 99% of the voltage from a power supply to the ultrasound transducer with minimal reflections. The device produces high-power acoustical energy waves while operating at lower voltages than conventional ultrasound driving systems because energy losses owing to mismatched impedance are minimized. The peak performance of the driver is measured experimentally with a PZT-4, 1.54 MHz, piezoelectric ceramic, and modeled using an adjusted Mason model over a range of transducer resonant frequencies. The ultrasound driver can deliver a 100 V(pp) (peak to peak) square-wave signal across 0-8 MHz ultrasound transducers in 5 ms bursts through continuous wave operation, producing acoustic powers exceeding 130 W. Effects of frequency, output impedance of the driver, and input impedance of the transducer on the maximum acoustic output power of piezoelectric transducers are examined. The small size, high power, and efficiency of the ultrasound driver make this technology useful for research, medical, and industrial ultrasonic applications.

  11. Consistency between subjectively and objectively measured hazard perception skills among young male drivers.

    PubMed

    Ābele, Līva; Haustein, Sonja; Møller, Mette; Martinussen, Laila M

    2018-03-01

    Young male drivers have lower hazard perception skills (HPS) than older and more experienced drivers and a tendency to overestimate their skills in hazardous situations. Both factors contribute to an over-representation in traffic accidents. Based on a sample of 63 drivers aged 18-24, this study compares the consistency of HPS measured by objective and subjective measures and the link between these measures is the key contribution of the study. Both visible and hidden hazards are included. Objective measures of HPS include responsiveness and eye movements while driving in a driving simulator. Subjective measures of HPS include self-reports derived based on the Hazard Perception Questionnaire (HPQ), Driving Skill Questionnaire (DSQ), and Brief Sensation Seeking Scale (BSSS). Results show that drivers who respond to the hazards on time, as compared to drivers who do not respond, have higher scores on subjective measures of HPS and higher driving skills in the visible but not in the hidden condition. Eye movement analysis confirms the difference and shows that response in time to hazards indicate higher HPS and young drivers are poor at detecting hidden hazards. Drivers with a response in time locate the hazard faster, have more fixations, but dwell less on the hazard. At the same time, those who do not respond have a later first fixation and fewer but longer fixations on the hazard. High sensation seeking drivers respond to visible hazards on time, suggesting that sensation seeking does not affect HPS negatively when the hazard is visible. To enhance the HPS among young drivers, the results of this study suggest that specific hazard perception training is relevant, especially for hazards that require more advanced HPS. Copyright © 2018 Elsevier Ltd. All rights reserved.

  12. How accurately do drivers evaluate their own driving behavior? An on-road observational study.

    PubMed

    Amado, Sonia; Arıkan, Elvan; Kaça, Gülin; Koyuncu, Mehmet; Turkan, B Nilay

    2014-02-01

    Self-assessment of driving skills became a noteworthy research subject in traffic psychology, since by knowing one's strenghts and weaknesses, drivers can take an efficient compensatory action to moderate risk and to ensure safety in hazardous environments. The current study aims to investigate drivers' self-conception of their own driving skills and behavior in relation to expert evaluations of their actual driving, by using naturalistic and systematic observation method during actual on-road driving session and to assess the different aspects of driving via comprehensive scales sensitive to different specific aspects of driving. 19-63 years old male participants (N=158) attended an on-road driving session lasting approximately 80min (45km). During the driving session, drivers' errors and violations were recorded by an expert observer. At the end of the driving session, observers completed the driver evaluation questionnaire, while drivers completed the driving self-evaluation questionnaire and Driver Behavior Questionnaire (DBQ). Low to moderate correlations between driver and observer evaluations of driving skills and behavior, mainly on errors and violations of speed and traffic lights was found. Furthermore, the robust finding that drivers evaluate their driving performance as better than the expert was replicated. Over-positive appraisal was higher among drivers with higher error/violation score and with the ones that were evaluated by the expert as "unsafe". We suggest that the traffic environment might be regulated by increasing feedback indicators of errors and violations, which in turn might increase the insight into driving performance. Improving self-awareness by training and feedback sessions might play a key role for reducing the probability of risk in their driving activity. Copyright © 2013 Elsevier Ltd. All rights reserved.

  13. National-level differences in the adoption of environmental health technologies: a cross-border comparison from Benin and Togo.

    PubMed

    Wendland, Kelly J; Pattanayak, Subhrendu K; Sills, Erin O

    2015-03-01

    Environmental health problems such as malaria, respiratory infections, diarrhoea and malnutrition pose very high burdens on the poor rural people in much of the tropics. Recent research on key interventions-the adoption and use of relatively cheap and effective environmental health technologies-has focused primarily on the influence of demand-side household-level drivers. Relatively few studies of the promotion and use of these technologies have considered the role of contextual factors such as governance, the enabling environment and national policies because of the challenges of cross-country comparisons. We exploit a natural experimental setting by comparing household adoption across the Benin-Togo national border that splits the Tamberma Valley in West Africa. Households across the border share the same culture, ethnicity, weather, physiographic features, livelihoods and infrastructure; however, they are located in countries at virtually opposite ends of the institutional spectrum of democratic elections, voice and accountability, effective governance and corruption. Binary choice models and rigorous non-parametric matching estimators confirm that households in Benin are more likely than households in Togo to plant soybeans, build improved cookstoves and purchase mosquito nets, ceteris paribus. Although we cannot identify the exact mechanism for the large and significant national-level differences in technology adoption, our findings suggest that contextual institutional factors can be more important than household characteristics for technology adoption. Published by Oxford University Press in association with The London School of Hygiene and Tropical Medicine © The Author 2014; all rights reserved.

  14. Thermoelectric applications as related to biomedical engineering for NASA Johnson Space Center

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kramer, C.D.

    1997-07-01

    This paper presents current NASA biomedical developments and applications using thermoelectrics. Discussion will include future technology enhancements that would be most beneficial to the application of thermoelectric technology. A great deal of thermoelectric applications have focused on electronic cooling. As with all technological developments within NASA, if the application cannot be related to the average consumer, the technology will not be mass-produced and widely available to the public (a key to research and development expenditures and thermoelectric companies). Included are discussions of thermoelectric applications to cool astronauts during launch and reentry. The earth-based applications, or spin-offs, include such innovations asmore » tank and race car driver cooling, to cooling infants with high temperatures, as well as, the prevention of hair loss during chemotherapy. In order to preserve the scientific value of metabolic samples during long-term space missions, cooling is required to enable scientific studies. Results of one such study should provide a better understanding of osteoporosis and may lead to a possible cure for the disease. In the space environment, noise has to be kept to a minimum. In long-term space applications such as the International Space Station, thermoelectric technology provides the acoustic relief and the reliability for food, as well as, scientific refrigeration/freezers. Applications and future needs are discussed as NASA moves closer to a continued space presence in Mir, International Space Station, and Lunar-Mars Exploration.« less

  15. Commercial phosphoric acid fuel cell system technology development

    NASA Technical Reports Server (NTRS)

    Prokopius, P. R.; Warshay, M.; Simons, S. N.; King, R. B.

    1979-01-01

    Reducing cost and increasing reliability were the technology drivers in both the electric utility and on-site integrated energy system applications. The longstanding barrier to the attainment of these goals was materials. Differences in approaches and their technological features, including electrodes, matrices, intercell cooling, bipolar/separator plates, electrolyte management, fuel selection, and system design philosophy were discussed.

  16. Subjective Norms as a Driver of Mass Communication Students' Intentions to Adopt New Media Production Technologies

    ERIC Educational Resources Information Center

    Hopp, Toby M.

    2013-01-01

    In this study, the impact of subjective norms on mass communication students' intentions to adopt new media production technologies was explored. The results indicated that subjective norms play an instrumental role in explaining behavioral intentions to adopt new media technologies. Moreover, the data indicated that public relations students…

  17. Drivers, challenges and opportunities of forage technology adoption by smallholder cattle households in Cambodia.

    PubMed

    Ashley, K; Wilson, S; Young, J R; Chan, H P; Vitou, S; Suon, S; Windsor, P A; Bush, R D

    2018-01-01

    Forage technology has been successfully introduced into smallholder cattle systems in Cambodia as an alternative feed source to the traditional rice straw and native pastures, improving animal nutrition and reducing labour requirements of feeding cattle. Previous research has highlighted the positive impacts of forage technology including improved growth rates of cattle and household time savings. However, further research is required to understand the drivers, challenges and opportunities of forage technology for smallholder cattle households in Cambodia to facilitate widespread adoption and identify areas for further improvement. A survey of forage-growing households (n = 40) in July-September 2016 examined forage technology adoption experiences, including reasons for forage establishment, use of inputs and labour requirements of forage plot maintenance and use of forages (feeding, fattening, sale of grass or seedlings and silage). Time savings was reported as the main driver of forage adoption with household members spending approximately 1 h per day maintaining forages and feeding it to cattle. Water availability was reported as the main challenge to this activity. A small number of households also reported lack of labour, lack of fencing, competition from natural grasses, cost of irrigation and lack of experience as challenges to forage growing. Cattle fattening and sale of cut forage grass and seedlings was not found to be a widespread activity by interviewed households, with 25 and 10% of households reporting use of forages for these activities, respectively. Currently, opportunities exist for these households to better utilise forages through expansion of forage plots and cattle activities, although assistance is required to support these households in addressing current constraints, particularly availability of water, if the sustainability of this feed technology for smallholder cattle household is to be established in Cambodia.

  18. Commercialization of new biotechnology: a systematic review of 16 commercial case studies in a novel manufacturing sector.

    PubMed

    Paul, Matthew J; Thangaraj, Harry; Ma, Julian K-C

    2015-10-01

    The 1980s and 1990s saw a major expansion of biotechnology into new areas of science including genomics and recombinant technologies. This was coupled to the widespread emergence of academics into the commercial sector as they were encouraged to spin out companies or commercialize their intellectual property. There were many opportunities to raise investment, and extraordinary success stories were prominent across many areas of technology. The field of plant biotechnology for manufacturing recombinant pharmaceuticals (molecular pharming) emerged and was developed in this period. Like other biotechnologies, this was an exciting new development which offered some very obvious benefits and commercial advantages. In particularly, plant molecular pharming represented a highly novel and potentially disruptive manufacturing technology for recombinant proteins. Twenty-five years on, a series of interviews with senior members of sixteen of the most prominent companies involved in the field provides insight into the original drivers for commercialization, strategic thinking and planning behind key commercial decisions and an insider view into the major reasons for commercial success or failure. These observations and recurring themes identified across a number of commercial ventures remain relevant today, as new biotech companies continue to spin out of the world of academia. © 2015 Society for Experimental Biology, Association of Applied Biologists and John Wiley & Sons Ltd.

  19. Equine road user safety: public attitudes, understandings and beliefs from a qualitative study in the United Kingdom.

    PubMed

    Chapman, Catherine; Musselwhite, Charles B A

    2011-11-01

    Horse riders represent a significant group of vulnerable road user and are involved in a number of accidents and near misses on the road. Despite this horse riders have received little attention both in terms of academic research and transport policy. Based on literature on vulnerable road user safety, including attitudes to road user safety and behaviour of drivers and their relationship with cyclists and motorcyclists, this paper examines the attitudes and reported behaviour of drivers and horse riders. A total of 46 participants took part in six focus groups divided into four groups of drivers with little or no horse riding experience and two groups of frequent horse riders. Each group investigated five key topic areas stemming from the literature review on vulnerable road users including hazard perception, risk perception, emotion, attitudes to sharing the road and empathy. It was found that drivers and horse riders are not always aware of the same hazards in the road and that this may lead drivers to under-estimate the risk when encountering horses. Drivers often had good intentions to overtake horses safely, but were unaware of how vulnerable passing very wide and slow made them feel until they had begun the manoeuvre and hence quickly reduced such feelings either by speeding up or cutting in too soon. However, other than this, drivers had good skills when encountering horses. But these skills could be impeded by frustration when encountering a slow moving horse which was further compounded by a feeling, mainly by younger drivers, that horse riding was for leisure and as such should not get in the way of necessary work journeys. There is a need for drivers to be more aware of the potential hazards a horse rider faces on the road and these could be achieved through inducing empathy amongst drivers for horse riders, creating nudges for drivers in the environment and better education for drivers. Copyright © 2011 Elsevier Ltd. All rights reserved.

  20. Driving behaviors in early stage dementia: a study using in-vehicle technology.

    PubMed

    Eby, David W; Silverstein, Nina M; Molnar, Lisa J; LeBlanc, David; Adler, Geri

    2012-11-01

    According to the Alzheimer's Association (2011), (1) in 8 people age 65 and older, and about one-half of people age 85 and older, have Alzheimer's disease in the United States (US). There is evidence that drivers with Alzheimer's disease and related dementias are at an increased risk for unsafe driving. Recent advances in sensor, computer, and telecommunication technologies provide a method for automatically collecting detailed, objective information about the driving performance of drivers, including those with early stage dementia. The objective of this project was to use in-vehicle technology to describe a set of driving behaviors that may be common in individuals with early stage dementia (i.e., a diagnosis of memory loss) and compare these behaviors to a group of drivers without cognitive impairment. Seventeen drivers with a diagnosis of early stage dementia, who had completed a comprehensive driving assessment and were cleared to drive, participated in the study. Participants had their vehicles instrumented with a suite of sensors and a data acquisition system, and drove 1-2 months as they would under normal circumstances. Data from the in-vehicle instrumentation were reduced and analyzed, using a set of algorithms/heuristics developed by the research team. Data from the early stage dementia group were compared to similar data from an existing dataset of 26 older drivers without dementia. The early stage dementia group was found to have significantly restricted driving space relative to the comparison group. At the same time, the early stage dementia group (which had been previously cleared by an occupational therapist as safe to drive) drove as safely as the comparison group. Few safety-related behavioral errors were found for either group. Wayfinding problems were rare among both groups, but the early stage dementia group was significantly more likely to get lost. Copyright © 2011 Elsevier Ltd. All rights reserved.

  1. Review of advanced driver assistance systems (ADAS)

    NASA Astrophysics Data System (ADS)

    Ziebinski, Adam; Cupek, Rafal; Grzechca, Damian; Chruszczyk, Lukas

    2017-11-01

    New cars can be equipped with many advanced safety solutions. Airbags, seatbelts and all of the essential passive safety parts are standard equipment. Now cars are often equipped with new advanced active safety systems that can prevent accidents. The functions of the Advanced Driver Assistance Systems are still growing. A review of the most popular available technologies used in ADAS and descriptions of their application areas are discussed in this paper.

  2. High-Throughput Functional Validation of Progression Drivers in Lung Adenocarcinoma

    DTIC Science & Technology

    2013-09-01

    2) a novel molecular barcoding approach that facilitates cost- effective detection of driver events following in vitro and in vivo functional screens...aberration construction pipeline, which we named High-Throughput 3 Mutagenesis and Molecular Barcoding (HiTMMoB; Fig.1). We have therefore been able...lentiviral vector specially constructed for this project. This vector is compatible with our flexible molecular barcoding technology (Fig. 1), thus each

  3. Simultaneous Identification of Multiple Driver Pathways in Cancer

    PubMed Central

    Leiserson, Mark D. M.; Blokh, Dima

    2013-01-01

    Distinguishing the somatic mutations responsible for cancer (driver mutations) from random, passenger mutations is a key challenge in cancer genomics. Driver mutations generally target cellular signaling and regulatory pathways consisting of multiple genes. This heterogeneity complicates the identification of driver mutations by their recurrence across samples, as different combinations of mutations in driver pathways are observed in different samples. We introduce the Multi-Dendrix algorithm for the simultaneous identification of multiple driver pathways de novo in somatic mutation data from a cohort of cancer samples. The algorithm relies on two combinatorial properties of mutations in a driver pathway: high coverage and mutual exclusivity. We derive an integer linear program that finds set of mutations exhibiting these properties. We apply Multi-Dendrix to somatic mutations from glioblastoma, breast cancer, and lung cancer samples. Multi-Dendrix identifies sets of mutations in genes that overlap with known pathways – including Rb, p53, PI(3)K, and cell cycle pathways – and also novel sets of mutually exclusive mutations, including mutations in several transcription factors or other genes involved in transcriptional regulation. These sets are discovered directly from mutation data with no prior knowledge of pathways or gene interactions. We show that Multi-Dendrix outperforms other algorithms for identifying combinations of mutations and is also orders of magnitude faster on genome-scale data. Software available at: http://compbio.cs.brown.edu/software. PMID:23717195

  4. A roadside study of observable driver distractions.

    PubMed

    Sullman, Mark J M; Prat, Francesc; Tasci, Duygu Kuzu

    2015-01-01

    This study investigated the prevalence of observable distractions while driving and the effect of drivers' characteristics and time-related variables on their prevalence. Using roadside observation, 2 independent observers collected data at 4 randomly selected locations in St. Albans, UK. Of the 10,984 drivers observed, 16.8% were engaged in a secondary task, with talking to passengers being the most common distraction (8.8%), followed by smoking (1.9%) and talking on a hands-free mobile phone (1.7%). An additional 1.0% were observed talking on a handheld phone, and the rest of the distractions (e.g., texting, drinking) were recorded in less than 1% of the drivers observed. Gender-related differences were found for a number of different distractions (i.e., talking to passengers, drinking, and handheld mobile phone conversations), but age emerged as a significant predictor for most secondary tasks, including talking to passengers, smoking, hands-free mobile phone use, handheld mobile phone use, texting/keying numbers, drinking, and engagement in any type of distraction (all distractions combined). The overall pattern for age was that middle-aged and older drivers were less likely to be distracted than younger drivers. This work provides further evidence of the relatively high rate of distracted driving in the UK. The findings clearly indicate that younger drivers are more likely to drive distracted, which probably contributes to their higher crash rates.

  5. Development of turbocharger for improving passenger car acceleration

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Watanabe, Tsuyoshi; Koike, Takaaki; Furukawa, Hiromu

    1996-09-01

    Recently, passenger cars require better acceleration from low engine speed including starting-up in order to decrease the amount of particulate matter (PM) of diesel engines or to improve the driver`s feeling. However, turbocharged cars generally have worse response than the non turbo cars because it takes a few seconds to get the turbocharger rotate up to high speed, usually called Turbo-lag. In order to solve this, various technologies have been developed for a turbocharger itself as well as for charging system such as the sequential system. Here in this paper, the authors focus on the development of the following turbochargermore » technology to reduce Turbo-lag and to achieve better transient response.« less

  6. "Taking the problem to the people": traffic safety from public relations to political theory, 1937-1954.

    PubMed

    Bernardin, Stève

    2015-04-01

    The slogan "taking the problem to the people" nicely summarizes U.S. traffic safety campaigns of the 1950s. It refers to the goal of awareness and self-discipline for drivers through education and law enforcement. A detailed analysis of the campaigns, however, shows a subtler objective of the motor interests that promoted it. They wanted to overcome political indifference through a civic mobilization of drivers as citizens, persuading drivers to lobby for traffic control. The analysis of their efforts leads us to question the role-or lack of role-of politicians in scientific and technological controversies.

  7. A power-efficient switchable CML driver at 10 Gbps

    NASA Astrophysics Data System (ADS)

    Peipei, Chen; Lei, Li; Huihua, Liu

    2016-02-01

    High static power limits the application of conventional current-mode logic(CML). This paper presents a power-efficient switchable CML driver, which achieves a significant current saving by 75% compared with conventional ones. Implemented in the 130 nm CMOS technology process, the proposed CML driver just occupies an area about 0.003 mm2 and provides a robust differential signal of 1600 mV for 10 Gbps optical line terminal (OLT) with a total current of 10 mA. The peak-to-peak jitter is about 4 ps (0.04TUI) and the offset voltage is 347.2 mV @ 1600 mVPP.

  8. OSIRIS and SOMBRERO Inertial Fusion Power Plant Designs, Volume 2: Designs, Assessments, and Comparisons

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Meier, W. R.; Bieri, R. L.; Monsler, M. J.

    1992-03-01

    This is a comprehensive design study of two Inertial Fusion Energy (IFE) electric power plants. Conceptual designs are presented for a fusion reactor (called Osiris) using an induction-linac heavy-ion beam driver, and another (called SOMBRERO) using a KrF laser driver. The designs covered all aspects of IFE power plants, including the chambers, heat transport and power conversion systems, balance-of-plant facilities, target fabrication, target injection and tracking, as well as the heavy-ion and KrF drivers. The point designs were assessed and compared in terms of their environmental & safety aspects, reliability and availability, economics, and technology development needs.

  9. Using scenarios of North Slope energy and resource development to assess research and monitoring needs

    NASA Astrophysics Data System (ADS)

    Payne, J. F.

    2016-12-01

    Significant Arctic environmental and socio-economic change has been observed on the North Slope of Alaska, presenting challenges for resident communities and management agencies that need to adapt to future changes that are difficult to model or predict. Continued climate change coupled with new or modified energy development could substantially alter the landscape and ecosystem in the future. The North Slope Science Initiative (NSSI) recognized the value of using a participatory scenarios process to consider plausible future energy and resource development scenarios through the year 2040 to help identify and prioritize research and monitoring needs on the North Slope. The scenarios process engaged diverse stakeholders, including subject matter experts and local knowledge holders. Through identification and ranking of key drivers and uncertainties relevant to the focus of the study, a series of spatially explicit scenarios was developed, analyzed in terms of low, medium and high development activities. Climate change and economic factors were key drivers affecting plausible energy development scenarios. The implications from each of the scenarios were then used to identify important research and monitoring activities and their relevant spatial scales. The scenarios project identified over 40 research and monitoring needs. The top five research needs addressed data gaps and key concerns related to how the scenarios could affect: hunting and trapping on land, health and community well-being, permafrost and hydrology, marine mammal subsistence and potential marine oil spills. The use of a participatory scenarios process was essential for identifying a range of plausible energy and resource development scenarios using a framework that involved a systematic assessment of complex interacting drivers of change, consideration of key uncertainties, and transparency throughout the project.

  10. Status report on renewable energy in the States

    NASA Astrophysics Data System (ADS)

    Swezey, B.; Sinclair, K.

    1992-12-01

    As the concept of integrated resource planning has spread among states and utilities, a reexamination of the role of renewable energy sources in the utility resource mix is taking place. This report documents the findings of a study of state regulatory commissions undertaken to: (1) help assess the state of knowledge and awareness about renewable energy resources and technologies; (2) assess the impacts of state policies on renewable energy development; and (3) identify important information needs. The key findings from this effort are: Renewable energy development has occurred only slowly over the last decade, and a small number of states account for the bulk of development. The development that has occurred has been limited to non-utility entities. Directed state policies have been a key driver in renewable energy development. Those states not currently addressing renewables may need more data and information before they proceed with directed policies. Other important observations are: The cost of renewables is an overriding concern. Regulators distinguish between 'emerging' and 'established' renewable energy technologies. Specific data are lacking on state-level renewable energy development. Detailed renewable resource assessments have yet to be performed in many states. This report identifies renewable energy information needs of state regulators. However, a number of concerns are also identified that must be addressed before renewables will receive serious attention in many of those states with limited renewables experience. Finally, the report catalogs a wide variety of policies that have been utilized in the states to promote greater development of renewable energy.

  11. The NHS: assessing new technologies, NICE and value for money.

    PubMed

    Stevens, A; Chalkidou, K; Littlejohns, P

    2011-06-01

    The healthcare system in the UK, essentially the NHS, is an open economic system subject to the same pressures as any other economic system. The pressures concern limited resources coupled with powerful drivers for increasing spending: invention, demography and inflation. There have only ever been three types of economic system: steady state (everything, as in a feudal system, stays as it was the year before), market capitalism (supply and demand are allowed to find their own equilibrium) and some version of central planning. In healthcare, most advanced countries favour the last of the three. This is for three reasons: distribution (not only are the poor less able to pay for sickness, but sickness exacerbates poverty), information (markets operate poorly when providers can easily outsmart customers) and externalities (it is in the interest of everyone that infectious diseases and the other knock-on consequences of ill health are ameliorated). So in the UK, the state, with a good deal of cross-party consensus, directs most of health service supply. This system has become more complex over the decades since the formation of the NHS in 1948. A notable element of the complexity is the regulation of the introduction of new technologies. A key element of the regulatory system has been the National Institute for Health and Clinical Excellence (NICE), and a key aspect of NICE's decisions has been not just value, but also value for money. This has not been without controversy.

  12. Demystifying governance and its role for transitions in urban social–ecological systems

    Treesearch

    T.A. Muñoz-Erickson; L.K. Campbell; D.L. Childers; J.M. Grove; D.M. Iwaniec; S.T.A. Pickett; Michelle Romolini; Erika S. Svendsen

    2016-01-01

    Governance is key to sustainable urban transitions. Governance is a system of social, power, and decision-making processes that acts as a key driver of resource allocation and use, yet ecologists even urban ecologists–seldom consider governance concepts in their work. Transitions to more sustainable futures are becoming increasingly important to the management of many...

  13. Evaluating Common Hypotheses for Violence in Central America

    DTIC Science & Technology

    2016-12-01

    53  Table 6.  Key Police Statistics , 2013 ........................................................................58  Table 7.  Length of...unemployment and the lack of social mobility as a key driver to delinquency , especially for young adult males.5 Some attribute increasing violence in...as well as statistics and other metrics that might reveal correlations between policies and violence rates. 13 II. EVALUATING THE STRUCTURAL

  14. A spatial database for restoration management capability on national forests in the Pacific Northwest USA

    Treesearch

    Chris Ringo; Alan A. Ager; Michelle A. Day; Sarah Crim

    2016-01-01

    Understanding the capacity to reduce wildfire risk and restore dry forests on Western national forests is a key part of prioritizing new accelerated restoration programs initiated by the Forest Service. Although a number of social and biophysical factors influence the ability to implement restoration programs, one key driver is the suite of forest plan land...

  15. Using smart card technology to prevent sales of alcohol to underage persons

    DOT National Transportation Integrated Search

    2001-07-01

    This report documents the results of a demonstration and evaluation project to examine the effectiveness of smart card technology (i.e., magnetic stripe on the driver's license and a card reader system) as a means of providing alcohol retailers with ...

  16. Stress Evaluation while Prolonged Driving Operation Using the Facial Skin Temperature

    NASA Astrophysics Data System (ADS)

    Asano, Hirotoshi; Muto, Takumi; Ide, Hideto

    There is a relation to the accident of a car and the physiological and psychological state of a driver. The stress may lead to the fall of a fatigue or attentiveness. Therefore, it is an important subject from viewpoint such as accident prevention to evaluate the mental state of a driver. The study aimed at the development of a quantitative instrumentation technology of the stress when a subject is driving for a long time. First of all, we measured the physiological and psychological stress of a driver. The facial skin temperature and ventricular rate that was driver's physiological amount were measured and compared it with visual analog scale of the subjective amount. It was able to be obtaining of the high correlation in facial skin temperature and visual analog scale from the outcome of the experiment. Therefore, the possibility of appreciable of driver's stress at a facial skin temperature was shown. As a result of the experiment, we showed a possibility that facial skin temperature could evaluate long driving stress.

  17. Driver Performance in the Moments Surrounding a Microsleep

    PubMed Central

    Boyle, Linda Ng; Tippin, Jon; Paul, Amit; Rizzo, Matthew

    2009-01-01

    This study examined if individuals who are at increased risk for drowsy-driving because of obstructive sleep apnea syndrome (OSAS), have impairments in driving performance in the moments during microsleep episodes as opposed to during periods of wakefulness. Twenty-four licensed drivers diagnosed with OSAS based on standard clinical and polysomnographic criteria, participated in an hour-long drive in a high-fidelity driving simulator with synchronous electroencephalographic (EEG) recordings for identification of microsleeps. The drivers showed significant deterioration in vehicle control during the microsleep episodes compared to driving performance in the absence of microsleeps on equivalent segments of roadway. The degree of performance decrement correlated with microsleep duration, particularly on curved roads. Results indicate that driving performance deteriorates during microsleep episodes. Detecting microsleeps in real-time and identifying how these episodes of transition between wakefulness and sleep impair driver performance is relevant to the design and implementation of countermeasures such as drowsy driver detection and alerting systems that use EEG technology. PMID:20090864

  18. Ka-band SAR interferometry studies for the SWOT mission

    NASA Astrophysics Data System (ADS)

    Fernandez, D. E.; Fu, L.; Rodriguez, E.; Hodges, R.; Brown, S.

    2008-12-01

    The primary objective of the NRC Decadal Survey recommended SWOT (Surface Water and Ocean Topography) Mission is to measure the water elevation of the global oceans, as well as terrestrial water bodies (such as rivers, lakes, reservoirs, and wetlands), to answer key scientific questions on the kinetic energy of ocean circulation, the spatial and temporal variability of the world's surface freshwater storage and discharge, and to provide societal benefits on predicting climate change, coastal zone management, flood prediction, and water resources management. The SWOT mission plans to carry the following suite of microwave instruments: a Ka-band interferometer, a dual-frequency nadir altimeter, and a multi-frequency water-vapor radiometer dedicated to measuring wet tropospheric path delay to correct the radar measurements. We are currently funded by the NASA Earth Science Technology Office (ESTO) Instrument Incubator Program (IIP) to reduce the risk of the main technological drivers of SWOT, by addressing the following technologies: the Ka-band radar interferometric antenna design, the on-board interferometric SAR processor, and the internally calibrated high-frequency radiometer. The goal is to significantly enhance the readiness level of the new technologies required for SWOT, while laying the foundations for the next-generation missions to map water elevation for studying Earth. The first two technologies address the challenges of the Ka-band SAR interferometry, while the high- frequency radiometer addresses the requirement for small-scale wet tropospheric corrections for coastal zone applications. In this paper, we present the scientific rational, need and objectives behind these technology items currently under development.

  19. Developing next-generation telehealth tools and technologies: patients, systems, and data perspectives.

    PubMed

    Ackerman, Michael J; Filart, Rosemarie; Burgess, Lawrence P; Lee, Insup; Poropatich, Ronald K

    2010-01-01

    The major goals of telemedicine today are to develop next-generation telehealth tools and technologies to enhance healthcare delivery to medically underserved populations using telecommunication technology, to increase access to medical specialty services while decreasing healthcare costs, and to provide training of healthcare providers, clinical trainees, and students in health-related fields. Key drivers for these tools and technologies are the need and interest to collaborate among telehealth stakeholders, including patients, patient communities, research funders, researchers, healthcare services providers, professional societies, industry, healthcare management/economists, and healthcare policy makers. In the development, marketing, adoption, and implementation of these tools and technologies, communication, training, cultural sensitivity, and end-user customization are critical pieces to the process. Next-generation tools and technologies are vehicles toward personalized medicine, extending the telemedicine model to include cell phones and Internet-based telecommunications tools for remote and home health management with video assessment, remote bedside monitoring, and patient-specific care tools with event logs, patient electronic profile, and physician note-writing capability. Telehealth is ultimately a system of systems in scale and complexity. To cover the full spectrum of dynamic and evolving needs of end-users, we must appreciate system complexity as telehealth moves toward increasing functionality, integration, interoperability, outreach, and quality of service. Toward that end, our group addressed three overarching questions: (1) What are the high-impact topics? (2) What are the barriers to progress? and (3) What roles can the National Institutes of Health and its various institutes and centers play in fostering the future development of telehealth?

  20. Dust/Regolith for Surface Exploration

    NASA Technical Reports Server (NTRS)

    Peters, Benjamin

    2017-01-01

    System-wide dust protection is a key design driver for xEMUsurface operations, and development of dust proof mechanisms, bearings, materials, and coatings coupled with specific operations and surface architecture development is critical for success.

  1. Payload software technology

    NASA Technical Reports Server (NTRS)

    1976-01-01

    A software analysis was performed of known STS sortie payload elements and their associated experiments. This provided basic data for STS payload software characteristics and sizes. A set of technology drivers was identified based on a survey of future technology needs and an assessment of current software technology. The results will be used to evolve a planned approach to software technology development. The purpose of this plan is to ensure that software technology is advanced at a pace and a depth sufficient to fulfill the identified future needs.

  2. Directions of management for the development of fuel-and-energy complex as the key driver of the social-and-economic development of regions

    NASA Astrophysics Data System (ADS)

    Mottaeva, Asiiat

    2017-10-01

    The article is dedicated to the problems of the participation of the energy enterprises in the social-and-economic development of the regions and municipalities. The complex of mechanisms of the implementation of the Energy strategy in the form of strategic initiatives of the development of the energy industry representing the complex inter-industry state-private long-term projects is presented in the article. The author considers the development of the energy industry to be the key driver of the social-and-economic development of regions. The author proves, that the increase in competitiveness of Russian energy, geographical and grocery diversification of export and improvement of quality of export products might allow to solve some problems of the development of national economy.

  3. Preface to the special section on human factors and automation in vehicles: designing highly automated vehicles with the driver in mind.

    PubMed

    Merat, Natasha; Lee, John D

    2012-10-01

    This special section brings together diverse research regarding driver interaction with advanced automotive technology to guide design of increasingly automated vehicles. Rapidly evolving vehicle automation will likely change cars and trucks more in the next 5 years than the preceding 50, radically redefining what it means to drive. This special section includes 10 articles from European and North American researchers reporting simulator and naturalistic driving studies. Little research has considered the consequences of fully automated driving, with most focusing on lane-keeping and speed control systems individually. The studies reveal two underlying design philosophies: automate driving versus support driving. Results of several studies, consistent with previous research in other domains, suggest that the automate philosophy can delay driver responses to incidents in which the driver has to intervene and take control from the automation. Understanding how to orchestrate the transfer or sharing of control between the system and the driver, particularly in critical incidents, emerges as a central challenge. Designers should not assume that automation can substitute seamlessly for a human driver, nor can they assume that the driver can safely accommodate the limitations of automation. Designers, policy makers, and researchers must give careful consideration to what role the person should have in highly automated vehicles and how to support the driver if the driver is to be responsible for vehicle control. As in other domains, driving safety increasingly depends on the combined performance of the human and automation, and successful designs will depend on recognizing and supporting the new roles of the driver.

  4. Future changes driving dietetics workforce supply and demand: future scan 2012-2022.

    PubMed

    Rhea, Marsha; Bettles, Craig

    2012-03-01

    The dietetics profession faces many workforce challenges and opportunities to ensure that registered dietitians (RDs) and dietetic technicians, registered (DTRs) are at the forefront of health and nutrition. The profession must prepare for new public priorities, changes in population, and the restructuring of how people learn and work, as well as new advances in science and technology. In September 2010, the Dietetics Workforce Demand Task Force, in consultation with a panel of thought leaders, identified 10 change drivers that affect dietetics workforce supply and demand. This future scan report provides an overview of eight of these drivers. Two change drivers-health care reform and population risk factors/nutrition initiatives-are addressed in separate technical articles. A change matrix has been included at the end of this executive summary. The matrix contains a summary of each change driver and its expected impact and is designed to present the drivers in the context of a larger, dynamic system of change in the dietetics profession. The impact of any of these change drivers individually and collectively in a dynamic system is uncertain. The outcome of any change driver is also uncertain. The dietetics profession faces many choices within each change driver to meet the workforce challenges and seize the opportunities for leadership and growth. Copyright © 2012 Academy of Nutrition and Dietetics. Published by Elsevier Inc. All rights reserved.

  5. Report of the Snowmass M6 Working Group on high intensity proton sources

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Weiren Chou and J. Wei

    The U.S. high-energy physics program needs an intense proton source, a 1-4 MW Proton Driver (PD), by the end of this decade. This machine will serve as a stand-alone facility that will provide neutrino superbeams and other high intensity secondary beams such as kaons, muons, neutrons, and anti-protons (cf. E1 and E5 group reports) and also serve as the first stage of a neutrino factory (cf. M1 group report). It can also be a high brightness source for a VLHC. Based on present accelerator technology and project construction experience, it is both feasible and cost-effective to construct a 1-4 MWmore » Proton Driver. Two recent PD design studies have been made, one at FNAL and the other at the BNL. Both designed PD's for 1 MW proton beams at a cost of about U.S. $200M (excluding contingency and overhead) and both designs were upgradeable to 4 MW. An international collaboration between FNAL, BNL and KEK on high intensity proton facilities is addressing a number of key design issues. The superconducting (sc) RF cavities, cryogenics, and RF controls developed for the SNS can be directly adopted to save R&D efforts, cost, and schedule. PD studies are also actively being pursued at Europe and Japan.« less

  6. Orthopedic Implant Value Drivers: A Qualitative Survey Study of Hospital Purchasing Administrators.

    PubMed

    Li, Chuan Silvia; Vannabouathong, Christopher; Sprague, Sheila; Bhandari, Mohit

    2015-01-01

    Osteoarthritis (OA) is a chronic, degenerative disease that is highly prevalent in the population, yet the factors that affect purchasing decisions related to this condition are poorly understood. A questionnaire was developed and administered to hospital executives across North America to determine the factors that affect purchasing decisions related to OA. Thirty-four individuals participated in the survey. Clinical evidence and cost effectiveness were deemed to be the most important factors in the process of making purchasing decisions. The most important considerations for adopting new technology were whether there was sufficient evidence in the literature, followed by thoughts of key opinion leaders, and cost of intervention/device. Ongoing research is still needed, but the current study allowed us to identify some trends in the data, providing new insight on how hospital purchasing decisions are made, which could have an immediate impact on those currently involved with making these decisions.

  7. Nanoreactors for green catalysis

    PubMed Central

    De Martino, M Teresa; Abdelmohsen, Loai K E A; Rutjes, Floris P J T

    2018-01-01

    Sustainable and environmentally benign production are key drivers for developments in the chemical industrial sector, as protecting our planet has become a significant element that should be considered for every industrial breakthrough or technological advancement. As a result, the concept of green chemistry has been recently defined to guide chemists towards minimizing any harmful outcome of chemical processes in either industry or research. Towards greener reactions, scientists have developed various approaches in order to decrease environmental risks while attaining chemical sustainability and elegancy. Utilizing catalytic nanoreactors for greener reactions, for facilitating multistep synthetic pathways in one-pot procedures, is imperative with far-reaching implications in the field. This review is focused on the applications of some of the most used nanoreactors in catalysis, namely: (polymer) vesicles, micelles, dendrimers and nanogels. The ability and efficiency of catalytic nanoreactors to carry out organic reactions in water, to perform cascade reaction and their ability to be recycled will be discussed. PMID:29719570

  8. Origins Space Telescope

    NASA Astrophysics Data System (ADS)

    Cooray, Asantha R.; Origins Space Telescope Study Team

    2017-01-01

    The Origins Space Telescope (OST) is the mission concept for the Far-Infrared Surveyor, a study in development by NASA in preparation for the 2020 Astronomy and Astrophysics Decadal Survey. Origins is planned to be a large aperture, actively-cooled telescope covering a wide span of the mid- to far-infrared spectrum. Its spectrographs will enable 3D surveys of the sky that will discover and characterize the most distant galaxies, Milky-Way, exoplanets, and the outer reaches of our Solar system. Origins will enable flagship-quality general observing programs led by the astronomical community in the 2030s. The Science and Technology Definition Team (STDT) would like to hear your science needs and ideas for this mission. The team can be contacted at firsurveyor_info@lists.ipac.caltech.edu. I will summarize the OST STDT, mission design and instruments, key science drivers, and the study plan over the next two years.

  9. Crowdsourced data for flood hydrology: Feedback from recent citizen science projects in Argentina, France and New Zealand

    NASA Astrophysics Data System (ADS)

    Le Coz, Jérôme; Patalano, Antoine; Collins, Daniel; Guillén, Nicolás Federico; García, Carlos Marcelo; Smart, Graeme M.; Bind, Jochen; Chiaverini, Antoine; Le Boursicaud, Raphaël; Dramais, Guillaume; Braud, Isabelle

    2016-10-01

    New communication and digital image technologies have enabled the public to produce large quantities of flood observations and share them through social media. In addition to flood incident reports, valuable hydraulic data such as the extent and depths of inundated areas and flow rate estimates can be computed using messages, photos and videos produced by citizens. Such crowdsourced data help improve the understanding and modelling of flood hazard. Since little feedback on similar initiatives is available, we introduce three recent citizen science projects which have been launched independently by research organisations to quantitatively document flood flows in catchments and urban areas of Argentina, France, and New Zealand. Key drivers for success appear to be: a clear and simple procedure, suitable tools for data collecting and processing, an efficient communication plan, the support of local stakeholders, and the public awareness of natural hazards.

  10. Wind Turbine Contingency Control Through Generator De-Rating

    NASA Technical Reports Server (NTRS)

    Frost, Susan; Goebel, Kai; Balas, Mark

    2013-01-01

    Maximizing turbine up-time and reducing maintenance costs are key technology drivers for wind turbine operators. Components within wind turbines are subject to considerable stresses due to unpredictable environmental conditions resulting from rapidly changing local dynamics. In that context, systems health management has the aim to assess the state-of-health of components within a wind turbine, to estimate remaining life, and to aid in autonomous decision-making to minimize damage to the turbine. Advanced contingency control is one way to enable autonomous decision-making by providing the mechanism to enable safe and efficient turbine operation. The work reported herein explores the integration of condition monitoring of wind turbines with contingency control to balance the trade-offs between maintaining system health and energy capture. The contingency control involves de-rating the generator operating point to achieve reduced loads on the wind turbine. Results are demonstrated using a high fidelity simulator of a utility-scale wind turbine.

  11. Designing Albaha Internet of Farming Architecture

    NASA Astrophysics Data System (ADS)

    Alahmadi, A.

    2017-04-01

    Up to now, most farmers in Albaha, Saudi Arabia are still practicing traditional way, which is not optimized in term of water usage, quality of product, etc. At the same time, nowadays ICT becomes a key driver for Innovation in Farming. In this project, we propose a smart Internet of farming system to assist farmers in Albaha to optimize their farm productivity by providing accurate information to the farmers the right time prediction to harvest, to fertilize, to watering and other activities related to the farming/agriculture technology. The proposed system utilizes wireless sensor cloud to capture remotely important data such as temperature, humidity, soil condition (moisture, water level), etc., and then they are sent to a storage servers at Albaha University cloud. An adaptive knowledge engine will process the captured data into knowledge and the farmers can retrieve the knowledge using their smartphones via the Internet.

  12. Vaccines as a global imperative--a business perspective.

    PubMed

    Stéphenne, Jean

    2011-06-01

    During the past thirty years, vaccines have experienced a renaissance. Advances in science, business, and distribution have transformed the field to the point where vaccines are recognized as a "best buy" in global health, a driver of pharmaceutical industry growth, and a key instrument of international development. With many new vaccines available and others on the horizon, the global community will need to explore new ways of ensuring access to vaccines in developing nations. So-called tiered pricing, which makes vaccines available at different prices for countries at different levels of economic development; innovative financing mechanisms such as advance market commitments or offers of long-term and high-volume contracts to vaccine producers; and technology transfers such as sharing intellectual property and production techniques among companies and countries can all play a part in bringing new life-saving vaccines for pneumonia, rotavirus, malaria, and other diseases to developing countries.

  13. ATLAST and JWST Segmented Telescope Design Considerations

    NASA Technical Reports Server (NTRS)

    Feinberg, Lee

    2016-01-01

    To the extent it makes sense, leverage JWST (James Webb Space Telescope) knowledge, designs, architectures. GSE (Ground Support Equipment) good starting point. Develop a full end-to-end architecture that closes. Try to avoid recreating the wheel except where needed. Optimize from there (mainly for stability and coronagraphy). Develop a scalable design reference mission (9.2 meters). Do just enough work to understand launch break points in aperture size Demonstrate 10 pm (phase modulation) stability is achievable on a design reference mission. A really key design driver is the most robust stability possible!!! Make design compatible with starshades. While segmented coronagraphs with high throughput and large bandpasses are important, make the system serviceable so you can evolve the instruments. Keep it room temperature to minimize the costs associated with cryo. Focus resources on the contrast problem. Start with the architecture and connect it to the technology needs.

  14. Tracking The Changing Landscape Of Corporate Wellness Companies.

    PubMed

    Abraham, Jean; White, Katie M

    2017-02-01

    The corporate wellness industry is diversifying and now includes legacy wellness companies, divisions of health plans or delivery systems, and new technology-focused solution enterprises. We conducted in-depth interviews with leaders in the industry to understand the changes in its supply side, the drivers of these changes, future trends, and their implications for employers and policy makers. Three key trends emerged from the interviews: The industry is expanding and becoming increasingly diverse and competitive; wellness companies are redefining their business models to promote a culture of health; and the value proposition of employee wellness programs is shifting from a return on investment to a new idea: value on investment. Our findings clarify wellness companies' innovations, their contributions to population health improvement efforts, and the need for additional evidence to demonstrate the value of the new generation of wellness products and services. Project HOPE—The People-to-People Health Foundation, Inc.

  15. Thermodynamics and Diffusion Coupling in Alloys—Application-Driven Science

    NASA Astrophysics Data System (ADS)

    Ågren, John

    2012-10-01

    As emphasized by Stokes (1997), the common assumption of a linear progression from basic research (science), via applied research, to technological innovations (engineering) should be questioned. In fact, society would gain much by supporting long-term research that stems from practical problems and has usefulness as a key word. Such research may be fundamental, and often, it cannot be distinguished from "basic" research if it were not for its different motivation. The development of the Calphad method and the more recent development of accompanying kinetic approaches for diffusion serve as excellent examples and are the themes of this symposium. The drivers are, e.g., the development of new materials, processes, and lifetime predictions. Many challenges of the utmost practical importance require long-term fundamental research. This presentation will address some of them, e.g., the effect of various ordering phenomena on activation barriers, and the strength and practical importance of correlation effects.

  16. International Space Weather Initiative (ISWI)

    NASA Technical Reports Server (NTRS)

    Gopalswamy, Nat; Davila, Joseph M.

    2010-01-01

    The International Space Weather Initiative (ISWI) is an international scientific program to understand the external drivers of space weather. The science and applications of space weather has been brought to prominence because of the rapid development of space based technology that is useful for all human beings. The ISWI program has its roots in the successful International Heliophysical Year (IHY) program that ran during 2007 - 2009. The primary objective of the ISWI program is to advance the space weather science by a combination of instrument deployment, analysis and interpretation of space weather data from the deployed instruments in conjunction with space data, and communicate the results to the public and students. Like the IHY, the ISWI will be a grass roots organization with key participation from national coordinators in cooperation with an international steering committee. This talk outlines the ISWI program including its organization and proposed activities.

  17. A Framework to Move Forward on the Path to Eco-innovation in the Construction Industry: Implications to Improve Firms' Sustainable Orientation.

    PubMed

    Segarra-Oña, María-del-Val; Peiró-Signes, Angel; Cervelló-Royo, Roberto

    2015-12-01

    This paper examines key aspects in the innovative behavior of the construction firms that determine their environmental orientation while innovating. Structural equation modeling was used and data of 222 firms retrieved from the Spanish Technological Innovation Panel (PITEC) for 2010 to analyse the drivers of environmental orientation of the construction firms during the innovation process. The results show that the environmental orientation is positively affected by the product and process orientation of construction firms during the innovation process. Furthermore, the positive relation between the importance of market information sources and environmental orientation, mediated by process and product orientation, is discussed. Finally, a model that explains these relations is proposed and validated. Results have important managerial implications for those companies worried about their eco-innovative focus as the types of actions and relations within firms most suitable for improving their eco-innovative orientation are highlighted.

  18. The impact of high-risk drivers and benefits of limiting their driving degree of freedom.

    PubMed

    Habtemichael, Filmon G; de Picado-Santos, Luis

    2013-11-01

    The perception of drivers regarding risk-taking behaviour is widely varied. High-risk drivers are the segment of drivers who are disproportionately represented in the majority of crashes. This study examines the typologies of drivers in risk-taking behaviour, the common high-risk driving errors (speeding, close following, abrupt lane-changing and impaired driving), their safety consequences and the technological (ITS) devices for their detection and correction. Limiting the driving degree of freedom of high-risk drivers is proposed and its benefits on safety as well as traffic operations are quantified using VISSIM microscopic traffic simulation at various proportions of high-risk drivers; namely, 4%, 8% and 12%. Assessment of the safety benefits was carried out by using the technique of simulated vehicle conflicts which was validated against historic crashes, and reduction in travel time was used to quantify the operational benefits. The findings imply that limiting the freedom of high-risk drivers resulted in a reduction of crashes by 12%, 21% and 27% in congested traffic conditions; 9%, 13% and 18% in lightly congested traffic conditions as well as 9%, 10% and 17% in non-congested traffic conditions for high-risk drivers in proportions of 4%, 8% and 12% respectively. Moreover, the surrogate safety measures indicated that there was a reduction in crash severity levels. The operational benefits amounted to savings of nearly 1% in travel time for all the proportions of high-risk drivers considered. The study concluded that limiting the freedom of high-risk drivers has safety and operational benefits; though there could be social, legal and institutional concerns for its practical implementation. Copyright © 2013 Elsevier Ltd. All rights reserved.

  19. Can vehicle longitudinal jerk be used to identify aggressive drivers? An examination using naturalistic driving data.

    PubMed

    Feng, Fred; Bao, Shan; Sayer, James R; Flannagan, Carol; Manser, Michael; Wunderlich, Robert

    2017-07-01

    This paper investigated the characteristics of vehicle longitudinal jerk (change rate of acceleration with respect to time) by using vehicle sensor data from an existing naturalistic driving study. The main objective was to examine whether vehicle jerk contains useful information that could be potentially used to identify aggressive drivers. Initial investigation showed that there are unique characteristics of vehicle jerk in drivers' gas and brake pedal operations. Thus two jerk-based metrics were examined: (1) driver's frequency of using large positive jerk when pressing the gas pedal, and (2) driver's frequency of using large negative jerk when pressing the brake pedal. To validate the performance of the two metrics, drivers were firstly divided into an aggressive group and a normal group using three classification methods (1) traveling at excessive speed (speeding), (2) following too closely to a front vehicle (tailgating), and (3) their association with crashes or near-crashes in the dataset. The results show that those aggressive drivers defined using any of the three methods above were associated with significantly higher values of the two jerk-based metrics. Between the two metrics the frequency of using large negative jerk seems to have better performance in identifying aggressive drivers. A sensitivity analysis shows the findings were largely consistent with varying parameters in the analysis. The potential applications of this work include developing quantitative surrogate safety measures to identify aggressive drivers and aggressive driving, which could be potentially used to, for example, provide real-time or post-ride performance feedback to the drivers, or warn the surrounding drivers or vehicles using the connected vehicle technologies. Copyright © 2017 Elsevier Ltd. All rights reserved.

  20. Using trip diaries to mitigate route risk and risky driving behavior among older drivers.

    PubMed

    Payyanadan, Rashmi P; Maus, Adam; Sanchez, Fabrizzio A; Lee, John D; Miossi, Lillian; Abera, Amsale; Melvin, Jacob; Wang, Xufan

    2017-09-01

    To reduce exposure to risky and challenging driving situations and prolong mobility and independence, older drivers self-regulate their driving behavior. But self-regulation can be challenging because it depends on drivers' ability to assess their limitations. Studies using self-reports, survey data, and hazard and risk perception tests have shown that driving behavior feedback can help older drivers assess their limitations and adjust their driving behavior. But only limited work has been conducted in developing feedback technology interventions tailored to meet the information needs of older drivers, and the impact these interventions have in helping older drivers self-monitor their driving behavior and risk outcomes. The vehicles of 33 drivers 65 years and older were instrumented with OBD2 devices. Older drivers were provided access to customized web-based Trip Diaries that delivered post-trip feedback of the routes driven, low-risk route alternatives, and frequency of their risky driving behaviors. Data were recorded over four months, with baseline driving behavior collected for one month. Generalized linear mixed effects regression models assessed the effects of post-trip feedback on the route risk and driving behaviors of older drivers. Results showed that post-trip feedback reduced the estimated route risk of older drivers by 2.9% per week, and reduced their speeding frequency on average by 0.9% per week. Overall, the Trip Diary feedback reduced the expected crash rate from 1 in 6172 trips to 1 in 7173 trips, and the expected speeding frequency from 46% to 39%. Thus providing older drivers with tailored feedback of their driving behavior and crash risk could help them appropriately self-regulate their driving behavior, and improve their crash risk outcomes. Copyright © 2016 Elsevier Ltd. All rights reserved.

  1. DEMONSTRATION OF A SCENARIO APPROACH FOR TECHNOLOGY ASSESSMENT: TRANSPORTATION SECTOR

    EPA Science Inventory

    EPA’s Office of Research and Development (ORD) is pursuing an Air Quality Assessment that will examine the potential consequences of global change on tropospheric ozone and particulate matter (PM) in the year 2050. Technological change is one of the most important drivers for th...

  2. Overview of NASA Power Technologies for Space and Aero Applications

    NASA Technical Reports Server (NTRS)

    Beach, Raymond F.

    2014-01-01

    To achieve the ambitious goals that NASA has outlined for the next decades considerable development of power technology will be necessary. This presentation outlines the development objectives for both the space and aero applications. It further looks at the various power technologies that support these objectives and examines drivers that will be a driving force for future development.

  3. Phosphoric Acid Fuel Cell Technology Status

    NASA Technical Reports Server (NTRS)

    Simons, S. N.; King, R. B.; Prokopius, P. R.

    1981-01-01

    A review of the current phosphoric acid fuel cell system technology development efforts is presented both for multimegawatt systems for electric utility applications and for multikilowatt systems for on-site integrated energy system applications. Improving fuel cell performance, reducing cost, and increasing durability are the technology drivers at this time. Electrodes, matrices, intercell cooling, bipolar/separator plates, electrolyte management, and fuel selection are discussed.

  4. Teachers' Experiences of Technology-Based Teaching and Learning in the Foundation Phase

    ERIC Educational Resources Information Center

    Hannaway, D. M.; Steyn, M. G.

    2017-01-01

    This paper presents one aspect of a larger scale doctoral study, namely the teachers' experiences of technology-based teaching and learning in the Foundation Phase. Technology is a huge driver of change and South African education has to change regularly to meet the requirements set out by the Department of Education, including the development of…

  5. Drivers and challenges of personal health systems in workplace health promotion.

    PubMed

    Ilvesmäki, Antti

    2007-01-01

    Novel technologies such as wearable sensors, electronic health diaries and personalized web services are thought to have the potential to improve population health in a cost- efficient manner. The use of personal health systems in workplace health promotion is of particular interest, since the workplace often provides an excellent setting and infrastructure to support health- related interventions. Compared to the elderly or those already debilitated by disease, working people are also generally more capable of taking advantage of information technology. Extant research on the use of ICT in health promotion has recognized several functional and technological requirements, but relatively little is known about other factors that affect the commercialization and adoption of such systems. This paper attempts to identify some economic and structural drivers and challenges that may be relevant to the success of personal health systems in workplace health promotion.

  6. Construct mine environment monitoring system based on wireless mesh network

    NASA Astrophysics Data System (ADS)

    Chen, Xin; Ge, Gengyu; Liu, Yinmei; Cheng, Aimin; Wu, Jun; Fu, Jun

    2018-04-01

    The system uses wireless Mesh network as a network transmission medium, and strive to establish an effective and reliable underground environment monitoring system. The system combines wireless network technology and embedded technology to monitor the internal data collected in the mine and send it to the processing center for analysis and environmental assessment. The system can be divided into two parts: the main control network module and the data acquisition terminal, and the SPI bus technology is used for mutual communication between them. Multi-channel acquisition and control interface design Data acquisition and control terminal in the analog signal acquisition module, digital signal acquisition module, and digital signal output module. The main control network module running Linux operating system, in which the transplant SPI driver, USB card driver and AODV routing protocol. As a result, the internal data collection and reporting of the mine are realized.

  7. Conceptual design of data acquisition and control system for two Rf driver based negative ion source for fusion R&D

    NASA Astrophysics Data System (ADS)

    Soni, Jigensh; Yadav, R. K.; Patel, A.; Gahlaut, A.; Mistry, H.; Parmar, K. G.; Mahesh, V.; Parmar, D.; Prajapati, B.; Singh, M. J.; Bandyopadhyay, M.; Bansal, G.; Pandya, K.; Chakraborty, A.

    2013-02-01

    Twin Source - An Inductively coupled two RF driver based 180 kW, 1 MHz negative ion source experimental setup is initiated at IPR, Gandhinagar, under Indian program, with the objective of understanding the physics and technology of multi-driver coupling. Twin Source [1] (TS) also provides an intermediate platform between operational ROBIN [2] [5] and eight RF drivers based Indian test facility -INTF [3]. A twin source experiment requires a central system to provide control, data acquisition and communication interface, referred as TS-CODAC, for which a software architecture similar to ITER CODAC core system has been decided for implementation. The Core System is a software suite for ITER plant system manufacturers to use as a template for the development of their interface with CODAC. The ITER approach, in terms of technology, has been adopted for the TS-CODAC so as to develop necessary expertise for developing and operating a control system based on the ITER guidelines as similar configuration needs to be implemented for the INTF. This cost effective approach will provide an opportunity to evaluate and learn ITER CODAC technology, documentation, information technology and control system processes, on an operational machine. Conceptual design of the TS-CODAC system has been completed. For complete control of the system, approximately 200 Nos. control signals and 152 acquisition signals are needed. In TS-CODAC, control loop time required is within the range of 5ms - 10 ms, therefore for the control system, PLC (Siemens S-7 400) has been chosen as suggested in the ITER slow controller catalog. For the data acquisition, the maximum sampling interval required is 100 micro second, and therefore National Instruments (NI) PXIe system and NI 6259 digitizer cards have been selected as suggested in the ITER fast controller catalog. This paper will present conceptual design of TS -CODAC system based on ITER CODAC Core software and applicable plant system integration processes.

  8. Crash probability estimation via quantifying driver hazard perception.

    PubMed

    Li, Yang; Zheng, Yang; Wang, Jianqiang; Kodaka, Kenji; Li, Keqiang

    2018-07-01

    Crash probability estimation is an important method to predict the potential reduction of crash probability contributed by forward collision avoidance technologies (FCATs). In this study, we propose a practical approach to estimate crash probability, which combines a field operational test and numerical simulations of a typical rear-end crash model. To consider driver hazard perception characteristics, we define a novel hazard perception measure, called as driver risk response time, by considering both time-to-collision (TTC) and driver braking response to impending collision risk in a near-crash scenario. Also, we establish a driving database under mixed Chinese traffic conditions based on a CMBS (Collision Mitigation Braking Systems)-equipped vehicle. Applying the crash probability estimation in this database, we estimate the potential decrease in crash probability owing to use of CMBS. A comparison of the results with CMBS on and off shows a 13.7% reduction of crash probability in a typical rear-end near-crash scenario with a one-second delay of driver's braking response. These results indicate that CMBS is positive in collision prevention, especially in the case of inattentive drivers or ole drivers. The proposed crash probability estimation offers a practical way for evaluating the safety benefits in the design and testing of FCATs. Copyright © 2017 Elsevier Ltd. All rights reserved.

  9. Exploring the effects of spatial autocorrelation when identifying key drivers of wildlife crop-raiding.

    PubMed

    Songhurst, Anna; Coulson, Tim

    2014-03-01

    Few universal trends in spatial patterns of wildlife crop-raiding have been found. Variations in wildlife ecology and movements, and human spatial use have been identified as causes of this apparent unpredictability. However, varying spatial patterns of spatial autocorrelation (SA) in human-wildlife conflict (HWC) data could also contribute. We explicitly explore the effects of SA on wildlife crop-raiding data in order to facilitate the design of future HWC studies. We conducted a comparative survey of raided and nonraided fields to determine key drivers of crop-raiding. Data were subsampled at different spatial scales to select independent raiding data points. The model derived from all data was fitted to subsample data sets. Model parameters from these models were compared to determine the effect of SA. Most methods used to account for SA in data attempt to correct for the change in P-values; yet, by subsampling data at broader spatial scales, we identified changes in regression estimates. We consequently advocate reporting both model parameters across a range of spatial scales to help biological interpretation. Patterns of SA vary spatially in our crop-raiding data. Spatial distribution of fields should therefore be considered when choosing the spatial scale for analyses of HWC studies. Robust key drivers of elephant crop-raiding included raiding history of a field and distance of field to a main elephant pathway. Understanding spatial patterns and determining reliable socio-ecological drivers of wildlife crop-raiding is paramount for designing mitigation and land-use planning strategies to reduce HWC. Spatial patterns of HWC are complex, determined by multiple factors acting at more than one scale; therefore, studies need to be designed with an understanding of the effects of SA. Our methods are accessible to a variety of practitioners to assess the effects of SA, thereby improving the reliability of conservation management actions.

  10. High-pressure portable pneumatic drive unit.

    PubMed

    Hete, B F; Savage, M; Batur, C; Smith, W A; Golding, L A; Nosé, Y

    1989-12-01

    The left ventricular assist device (LVAD) of the Cleveland Clinic Foundation (CCF) is a single-chamber assist pump, driven by a high-pressure pneumatic cylinder. A low-cost, portable driver that will allow cardiac care patients, with a high-pressure pneumatic ventricle assist, more freedom of movement has been developed. The compact and light-weight configuration can provide periods of 2 h of freedom from a fixed position driver and does not use exotic technology.

  11. Laser targets compensate for limitations in inertial confinement fusion drivers

    NASA Astrophysics Data System (ADS)

    Kilkenny, J. D.; Alexander, N. B.; Nikroo, A.; Steinman, D. A.; Nobile, A.; Bernat, T.; Cook, R.; Letts, S.; Takagi, M.; Harding, D.

    2005-10-01

    Success in inertial confinement fusion (ICF) requires sophisticated, characterized targets. The increasing fidelity of three-dimensional (3D), radiation hydrodynamic computer codes has made it possible to design targets for ICF which can compensate for limitations in the existing single shot laser and Z pinch ICF drivers. Developments in ICF target fabrication technology allow more esoteric target designs to be fabricated. At present, requirements require new deterministic nano-material fabrication on micro scale.

  12. Effects of Viscosity on the Performance of Air-Powered Liquid Jet Injectors

    NASA Astrophysics Data System (ADS)

    Portaro, Rocco; Jaber, Hadi; Ng, Hoi Dick

    2017-11-01

    Drug delivery without the use of hypodermic needles has been a long-term objective within the medical field. This study focuses on observing the effects of drug viscosity on injector performance for air-powered liquid jet injectors, as well as the viability of using this technology for delivering viscous-type medications such as monoclonal antibodies. The experiments are conducted through the use of a prototype injector which allows key parameters such as driver pressure, injection volume and nozzle size to be varied. Different viscosities which range from 0.9 cP to 87 cP are obtained by using a water-glycerol mix. The liquid jets emanating from the injector are assessed using high speed photography as well as a pressure transducer. Experimental findings are then compared to a CFD model which considered experimental geometry and parameters. The results of this study highlight the effect of viscosity on the operating pressure of the injector and the reduction in jet stagnation pressure. It also illustrates improved jet confinement as viscosity is increased, a finding which is in line with the numerical model, and should play a key role in improving the device's characteristics for puncturing skin.

  13. "Head up and eyes out" advances in head mounted displays capabilities

    NASA Astrophysics Data System (ADS)

    Cameron, Alex

    2013-06-01

    There are a host of helmet and head mounted displays, flooding the market place with displays which provide what is essentially a mobile computer display. What sets aviators HMDs apart is that they provide the user with accurate conformal information embedded in the pilots real world view (see through display) where the information presented is intuitive and easy to use because it overlays the real world (mix of sensor imagery, symbolic information and synthetic imagery) and enables them to stay head up, eyes out, - improving their effectiveness, reducing workload and improving safety. Such systems are an enabling technology in the provision of enhanced Situation Awareness (SA) and reducing user workload in high intensity situations. Safety Is Key; so the addition of these HMD functions cannot detract from the aircrew protection functions of conventional aircrew helmets which also include life support and audio communications. These capabilities are finding much wider application in new types of compact man mounted audio/visual products enabled by the emergence of new families of micro displays, novel optical concepts and ultra-compact low power processing solutions. This papers attempts to capture the key drivers and needs for future head mounted systems for aviation applications.

  14. The co-occurrence of driver mutations in chronic myeloproliferative neoplasms.

    PubMed

    Boddu, Prajwal; Chihara, Dai; Masarova, Lucia; Pemmaraju, Naveen; Patel, Keyur P; Verstovsek, Srdan

    2018-06-27

    Myeloproliferative neoplasms (MPNs) are clonal disorders characterized by proliferation of one or more elements of the myeloid lineage. Key genetic aberrations include the BCR-ABL1 gene rearrangement in Philadelphia chromosome-positive chronic myelogenous leukemia (CML) and JAK2/MPL/CALR aberrations in Philadelphia chromosome-negative MPNs. While thought to be mutually exclusive, occasional isolated reports of coexistence of BCR-ABL1 and JAK2, and JAK2 with MPL or CALR aberrations have been described. Given the paucity of data, clinical characteristics and outcome of patients harboring concurrent Philadelphia-positive and Philadelphia-negative mutations or dual Philadelphia-negative driver mutations have not been systematically evaluated, and their clinical relevance is largely unknown. It is difficult to determine the true relevance of co-existing driver mutations on outcomes given the rarity of its occurrence. In this case series, we describe those patients who had dual driver mutations detected at any point during the course of their disease and characterized their clinical and laboratory features, bone marrow pathology, and overall disease course.

  15. Development of the physics driver in NOAA Environmental Modeling System (NEMS)

    NASA Astrophysics Data System (ADS)

    Lei, H.; Iredell, M.; Tripp, P.

    2016-12-01

    As a key component of the Next Generation Global Prediction System (NGGPS), a physics driver is developed in the NOAA Environmental Modeling System (NEMS) in order to facilitate the research, development, and transition to operations of innovations in atmospheric physical parameterizations. The physics driver connects the atmospheric dynamic core, the Common Community Physics Package and the other NEMS-based forecast components (land, ocean, sea ice, wave, and space weather). In current global forecasting system, the physics driver has incorporated major existing physics packages including radiation, surface physics, cloud and microphysics, ozone, and stochastic physics. The physics driver is also applicable to external physics packages. The structure adjustment in NEMS by separating the PHYS trunk is to create an open physics package pool. This open platform is beneficial to the enhancement of U.S. weather forecast ability. In addition, with the universal physics driver, the NEMS can also be used for specific functions by connecting external target physics packages through physics driver. The test of its function is to connect a physics dust-radiation model in the system. Then the modified system can be used for dust storm prediction and forecast. The physics driver is also developed into a standalone form. This is to facilitate the development works on physics packages. The developers can save instant fields of meteorology data and snapshots from the running system , and then used them as offline driving data fields to test the new individual physics modules or small modifications to current modules. This prevents the run of whole system for every test.

  16. Productivity, biodiversity, and pathogens influence the global hunter-gatherer population density.

    PubMed

    Tallavaara, Miikka; Eronen, Jussi T; Luoto, Miska

    2018-02-06

    The environmental drivers of species distributions and abundances are at the core of ecological research. However, the effects of these drivers on human abundance are not well-known. Here, we report how net primary productivity, biodiversity, and pathogen stress affect human population density using global ethnographic hunter-gatherer data. Our results show that productivity has significant effects on population density globally. The most important direct drivers, however, depend on environmental conditions: biodiversity influences population density exclusively in low-productivity regions, whereas pathogen stress does so in high-productivity regions. Our results also indicate that subtropical and temperate forest biomes provide the highest carrying capacity for hunter-gatherer populations. These findings document that environmental factors play a key role in shaping global population density patterns of preagricultural humans.

  17. [Transports: a strategic sector for our society].

    PubMed

    Giordano, R

    2012-01-01

    Transports are transmission belt of economies of different Countries. The time is the key variable, hence the economic finalism of transports that now is a theme of economic policy. The road transport sector, passengers and goods, is still a dominant sector that needs to be regulated in a market logic under the safety constraint understood in a system logic: infrastructure-vehicle-driver. The safety factor, understood as road and job safety, remains centered on the policies of intervention related to driver, whereas the most accidents in fact are due to factors related to human error and they cost in terms of social cost about 30 billion per year. The drivers' safety of commercial vehicles, professional vehicles, is a "human capital" that is little explored and that must be preserved.

  18. Problem-solving tools for analyzing system problems. The affinity map and the relationship diagram.

    PubMed

    Lepley, C J

    1998-12-01

    The author describes how to use two management tools, an affinity map and a relationship diagram, to define and analyze aspects of a complex problem in a system. The affinity map identifies the key influencing elements of the problem, whereas the relationship diagram helps to identify the area that is the most important element of the issue. Managers can use the tools to draw a map of problem drivers, graphically display the drivers in a diagram, and use the diagram to develop a cause-and-effect relationship.

  19. A trial of retrofitted advisory collision avoidance technology in government fleet vehicles.

    PubMed

    Thompson, James P; Mackenzie, Jamie R R; Dutschke, Jeffrey K; Baldock, Matthew R J; Raftery, Simon J; Wall, John

    2018-06-01

    In-vehicle collision avoidance technology (CAT) has the potential to prevent crash involvement. In 2015, Transport for New South Wales undertook a trial of a Mobileye 560 CAT system that was installed in 34 government fleet vehicles for a period of seven months. The system provided headway monitoring, lane departure, forward collision and pedestrian collision warnings, using audio and visual alerts. The purpose of the trial was to determine whether the technology could change the driving behaviour of fleet vehicle drivers and improve their safety. The evaluation consisted of three components: (1) analysis of objective data to examine effects of the technology on driving behaviour, (2) analysis of video footage taken from a sample of the vehicles to examine driving circumstances that trigger headway monitoring and forward collision warnings, and (3) a survey completed by 122 of the 199 individuals who drove the trial vehicles to examine experiences with, and attitudes to, the technology. Analysis of the objective data found that the system resulted in changes in behaviour with increased headway and improved lane keeping, but that these improvements dissipated once the warning alerts were switched off. Therefore, the system is capable of altering behaviour but only when it is actively providing alerts. In-vehicle video footage revealed that over a quarter of forward collision warnings were false alarms, in which a warning event was triggered despite there being no vehicle travelling ahead. The surveyed drivers recognised that the system could improve safety but most did not wish to use it themselves as they found it to be distracting and felt that it would not prevent them from having a crash. The results demonstrate that collision avoidance technology can improve driving behaviour but drivers may need to be educated about the potential benefits for their driving in order to accept the technology. Copyright © 2018 Elsevier Ltd. All rights reserved.

  20. Differences in glance behavior between drivers using a rearview camera, parking sensor system, both technologies, or no technology during low-speed parking maneuvers.

    PubMed

    Kidd, David G; McCartt, Anne T

    2016-02-01

    This study characterized the use of various fields of view during low-speed parking maneuvers by drivers with a rearview camera, a sensor system, a camera and sensor system combined, or neither technology. Participants performed four different low-speed parking maneuvers five times. Glances to different fields of view the second time through the four maneuvers were coded along with the glance locations at the onset of the audible warning from the sensor system and immediately after the warning for participants in the sensor and camera-plus-sensor conditions. Overall, the results suggest that information from cameras and/or sensor systems is used in place of mirrors and shoulder glances. Participants with a camera, sensor system, or both technologies looked over their shoulders significantly less than participants without technology. Participants with cameras (camera and camera-plus-sensor conditions) used their mirrors significantly less compared with participants without cameras (no-technology and sensor conditions). Participants in the camera-plus-sensor condition looked at the center console/camera display for a smaller percentage of the time during the low-speed maneuvers than participants in the camera condition and glanced more frequently to the center console/camera display immediately after the warning from the sensor system compared with the frequency of glances to this location at warning onset. Although this increase was not statistically significant, the pattern suggests that participants in the camera-plus-sensor condition may have used the warning as a cue to look at the camera display. The observed differences in glance behavior between study groups were illustrated by relating it to the visibility of a 12-15-month-old child-size object. These findings provide evidence that drivers adapt their glance behavior during low-speed parking maneuvers following extended use of rearview cameras and parking sensors, and suggest that other technologies which augment the driving task may do the same. Copyright © 2015 Elsevier Ltd. All rights reserved.

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